[Federal Register Volume 66, Number 139 (Thursday, July 19, 2001)]
[Notices]
[Page 37657]
From the Federal Register Online via the Government Publishing Office [www.gpo.gov]
[FR Doc No: 01-18010]


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DEPARTMENT OF DEFENSE

Department of the Army


Availability for Non-Exclusive, Exclusive, or Partially Exclusive 
Licensing of U.S. Patent Application Concerning Immobilized Enzymes as 
Biosensors for Chemical Toxins

AGENCY: U.S. Army Medical Research and Materiel Command, DoD.

ACTION: Notice.

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SUMMARY: In accordance with 37 CFR 404.6, announcement is made of the 
availability for licensing of U.S. Patent Application No. 09/558,511 
entitled ``Immobilized Enzymes as Biosensors for Chemical Toxins'' 
filed April 26, 2000. This patent has been assigned to the United 
States Government as represented by the Secretary of the Army.

ADDRESSES: Commander, U.S. Army Medical Research and Materiel Command, 
ATTN: Command Judge Advocate, MCMR-JA, 504 Scott Street, Fort Detrick, 
Frederick, Maryland 21702-5012.

FOR FURTHER INFORMATION CONTACT: For patent issues, Ms. Elizabeth 
Arwine, Patent Attorney, (301) 619-7808. For licensing issues, Dr. Paul 
Mele, Office of Research & Technology Assessment, (301) 619-6664. Both 
at telefax (301) 619-5034.

SUPPLEMENTARY INFORMATION: Methods, compositions and materials useful 
in the detection of organophosphorus and organosulfur compounds are 
disclosed. In particular. biosensors wherein a porous or a non-porous 
support having any enzyme immobilized upon or within are disclosed. The 
biosensors exhibit enzymatic stability at extreme temperatures and/or 
denaturing conditions, and similar kinetic characteristics of the 
soluble form of the enzymes utilized. The enzyme does not leach from 
the porous or non-porous support and the material retains enzymatic 
activity after prolonged storage. Differential biosensors are also 
disclosed.

Luz D. Ortiz,
Army Federal Register Liaison Officer.
[FR Doc. 01-18010 Filed 7-18-01; 8:45 am]
BILLING CODE 3710-08-M