[Federal Register Volume 66, Number 119 (Wednesday, June 20, 2001)]
[Notices]
[Page 33054]
From the Federal Register Online via the Government Publishing Office [www.gpo.gov]
[FR Doc No: 01-15448]


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DEPARTMENT OF DEFENSE

Department of the Navy


Notice of Availability of Government-Owned Invention; Available 
for Licensing

AGENCY: Department of the Navy, DOD.

ACTION: Notice.

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SUMMARY: The Department of the Navy hereby gives notice of the general 
availability of exclusive or partially exclusive licenses under the 
following pending patent. Any license granted shall comply with 35 
U.S.C. 209 and 37 CFR part 404. Applications will be evaluated 
utilizing the following criteria: (1) Ability to manufacture and market 
the technology; (2) manufacturing and marketing ability; (3) time 
required to bring technology to market and production rate; (4) 
royalties; (5) technical capabilities; and (6) small business status.
    Patent application Serial Number 09/747,521 entitled ``Methods for 
Protection Against Lethal Infection with Bacillus Anthracis'' filed 21 
December 2000. The present invention relates to the use selected genes 
from the pathogen Bacillus anthracis for constructing a plasmid or DNA-
based vaccine which can be used to immunize susceptible hosts against 
the pathogenic effects of B. anthracis infection. Moreover, the 
invention describes the protective effects of immunization with DNA 
constructs encoding the Protective Antigen (PA) or the Lethal Factor 
(LF) and mutants thereof. Most importantly, the invention describes the 
complete protection of hosts following co-immunization of a host with 
PA and LF demonstrating a surprising synergistic effect. Lastly, the 
invention teaches the use of the synergistic effect of PA and/or LF 
genes for use as a general adjuvant for co-immunization with other DNA 
or protein based vaccines.

DATES: Applications for an exclusive or partially exclusive license may 
be submitted at any time from the date of this notice.

ADDRESSES: The Office of Technology Transfer, Naval Medical Research 
Center, 503 Robert Grant Ave., Silver Spring, MD 20910-7500, telephone 
(301) 319-7428.

FOR FURTHER INFORMATION CONTACT: Dr. Charles Schlagel, Director, Office 
of Technology Transfer, Naval Medical Research Center, 503 Robert Grant 
Ave., Silver Spring, MD 20910-7500, telephone (301) 319-7428 or E-Mail 
at [email protected].

    Dated: June 11, 2001.
J.L. Roth,
Lieutenant Commander, Judge Advocate General's Corps, U.S. Navy, 
Federal Register Liaison Officer.
[FR Doc. 01-15448 Filed 6-19-01; 8:45 am]
BILLING CODE 3810-FF-P