[Federal Register Volume 65, Number 246 (Thursday, December 21, 2000)]
[Notices]
[Pages 80436-80437]
From the Federal Register Online via the Government Publishing Office [www.gpo.gov]
[FR Doc No: 00-32548]


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DEPARTMENT OF HEALTH AND HUMAN SERVICES

Centers for Disease Control and Prevention

[30DAY-08-01]


Agency Forms Undergoing Paperwork Reduction Act Review

    The Centers for Disease Control and Prevention (CDC) publishes a 
list of information collection requests under review by the Office of 
Management and Budget (OMB) in compliance with the Paperwork Reduction 
Act (44 U.S.C. Chapter 35). To request a copy of these requests, call 
the CDC Reports Clearance Officer at (404) 639-7090. Send written 
comments to CDC, Desk Officer; Human Resources and Housing Branch, New 
Executive Office Building, Room 10235; Washington, DC 20503. Written 
comments should be received within 30 days of this notice.

Proposed Project

    Thyroid Disease in Persons Exposed to Radioactive Fallout From 
Atomic Weapons Testing at the Nevada Test Site: Phase III--NEW--
National Center for Environmental Health (NCEH), Centers for Disease 
Control and Prevention (CDC). In 1997, the National Cancer Institute 
(NCI) released a report entitled, Estimated Exposures and Thyroid Doses 
Received by the American People from I-131 in Fallout Following Nevada 
Nuclear Bomb Test. This report provided county-level estimates of the 
potential radiation doses to the thyroid gland of American citizens 
resulting from atmospheric nuclear weapons testing at the Nevada Test 
Site (NTS) in the 1950's and 1960's. The Institute of Medicine (IOM) 
conducted a formal peer review of the report at the request of the 
Department of Health and Human Services. In the review, IOM noted that 
the public might desire an assessment of the potential health impact of 
nuclear weapons testing on American populations. The IOM also suggested 
that further studies of the Utah residents who have participated in 
previous studies of radiation exposure and thyroid disease might 
provide this information.
    The National Center for Environmental Health (NCEH), Centers for 
Disease Control and Prevention (CDC), proposes to conduct a study of 
the relation between exposure to radioactive fallout from atomic 
weapons testing and the occurrence of thyroid disease on an extension 
of a cohort study previously conducted by the University of Utah, Salt 
Lake City, Utah. This study is designed as a follow-up to a 
retrospective cohort study begun in 1965. This is the third examination 
(hence Phase III) of a cohort of individuals who were children living 
in Washington County, Utah, and Lincoln County, Nevada, in 1965 (Phase 
I) and who were presumably exposed to fallout from above-ground nuclear 
weapons testing at the Nevada Test Site in the 1950s. The cohort also 
includes a control group who were children living in Graham County, 
Arizona, in 1966 and presumably unexposed to fallout.
    The study headquarters will be at the University of Utah in Salt 
Lake City, Utah. The field teams will spend the majority of their time 
in the urban areas nearest the original counties if the same pattern of 
migration holds that was found in Phase II. These urban areas include 
St. George, Utah, the Wasatch Front in Utah, Las Vegas, Nevada, 
Phoenix/Tucson, Arizona, and Denver, Colorado. In addition, some time 
will be spent in California as a number of subjects had relocated there 
at the time of Phase II.
    The purposes of Phase III are three fold: First to re-examine the 
participants in Phase II for occurrence of thyroid neoplasia and other 
diseases since 1986. Residents of the three counties who moved before 
they could be included in the original cohort will be located and 
examined. Second, disease incidence will be analyzed in addition to 
period prevalence as used in the Phase II analysis. Use of incidence 
will allow for greater power to detect increased risk of disease in the 
exposed population through the use of person-time. Third, disease 
specific mortality rates for Washington County, Utah, and a control 
county, Cache County, Utah, will be compared for people who lived in 
these two counties during the time of above-ground testing.

------------------------------------------------------------------------
                                                               Average
                                  Number of    Responses/      burden
          Respondents            respondents   respondent     response
                                                                (hrs)
------------------------------------------------------------------------
Telephone Location Script.....          4800             1          5/60
Telephone Location Script                240             1          5/60
 (Return Letter)..............
Refusal Telephone Script......            48             1          5/60
New Person Location Telephone           2400             1          5/60
 Script.......................
Recruitment Next of Kin                  240             1          5/60
 Telephone Script.............
Questionnaire Not Returned                48             1          5/60
 Script #1 (New)..............
Questionnaire Not Returned                12             1          5/60
 Script #2 (New)..............
Recruitment & Appointment               4800             1          5/60
 Script.......................
Broken Appointment Telephone             240             1          5/60
 Script.......................
New Parent Recruitment &                 120             1          5/60
 Appointment Script...........
New Parent Alternate                      60             1          5/60
 Recruitment Script...........
Other New Parent Recruitment &            30             1          5/60
 Appointment..................
Other Parent or Relative                  30             1          5/60
 Permissions Script...........
Exposure Questionnaire........          2400             1             1
Questionnaire Preparation               2400             1         30/60
 Booklet......................
Group Member Information......          4800             1          5/60
Consent Forms.................          4800             1         10/60

[[Page 80437]]

 
Interview Booklet.............          4800             1         30/60
Medical History Questionnaire           2400             1             1
 (male).......................
Medical Records Release                  240             1          5/60
 Telephone Script.............
Medical History Questionnaire           2400             1             1
 (female).....................
Travel Form...................           480             1         20/60
Residence History.............          2400             1          5/60
Refusal Questionnaire.........            48             1          5/60
------------------------------------------------------------------------

    This comparison will determine if the risk of mortality in 
Washington County (the exposed group) is significantly greater than 
Cache County (the control group). CDC/NCEH is requesting a three-year 
clearance. The annual burden hours are estimated to be 13,607.

    Dated: December 15, 2000.
Nancy Cheal,
Acting Associate Director for Policy, Planning, and Evaluation Centers 
for Disease Control and Prevention (CDC).
[FR Doc. 00-32548 Filed 12-20-00; 8:45 am]
BILLING CODE 4163-18-P