[Federal Register Volume 65, Number 244 (Tuesday, December 19, 2000)]
[Notices]
[Pages 79374-79375]
From the Federal Register Online via the Government Publishing Office [www.gpo.gov]
[FR Doc No: 00-32234]


-----------------------------------------------------------------------

DEPARTMENT OF HEALTH AND HUMAN SERVICES

National Institutes of Health


Submission for OMB Review; Comment Request; The Family Health 
Study (Validation of a Family History of Cancer Questionnaire for Risk 
Factor Surveillance)

SUMMARY: Under the provisions of Section 3507(a)(1)(D) of the Paperwork 
Reduction Act of 1995, the National Cancer Institute (NCI), the 
National Institutes of Health (NIH) has submitted to the Office of 
Management and Budget (OMB) a request to review and approve the 
information collection listed below. This proposed information 
collection was previously published in the Federal

[[Page 79375]]

Register on June 7, 2000, page 36149-36159 and allowed 60 days for 
public comment. No public comments were received. The purpose of this 
notice is to allow an additional 30 days for public comment. The 
National Institutes of Health may not conduct or sponsor, and the 
respondent is not required to respond to, an information collection 
that has been extended, revised, or implemented on or after October 1, 
1995, unless it displays a currently valid OMB control number.

Proposed Collection

    Title: The Family Health Study (Validation of a Family History of 
Cancer Questionnaire for Risk Factor Surveillance).
    Type of Information Collection Request: NEW.
    Need and Use of Information Collection: In this methodologic pilot 
study, the NCI will develop a family history of cancer questionnaire 
for use in cancer risk factor surveillance, and will evaluate how 
accurately individuals in the general population can report major 
cancers occurring in their immediate and extended family. This study is 
needed because there are currently no validated questionnaires with 
which to collect comprehensive data for assessing the burden of family 
history of cancer in the U.S. population, and no general population 
estimates of reporting error for the major cancers that affect 
families. The results on reporting accuracy will be used to determine 
whether the quality of data is sufficient to justify conducting a 
comprehensive national prevalence study of family history of cancer. 
The questionnaire will be administered in a telephone survey of adults, 
age 25 to 64 years who will be randomly selected from households in 
Connecticut. Respondents will be asked to report about family structure 
and cancer diagnoses occurring in their first and second degree 
relatives. Positive and negative reports of five major cancer sites 
(i.e breast, prostate, colorectal, lung, and ovarian cancers) will be 
validated for approximately three relatives per respondent through data 
linkage to state and federal health registries or by review of death 
certificates and medical records. Living relatives and next-of-kin of 
deceased relatives may be interviewed as part of the validation 
process. Information about the accuracy of reports and factors 
associated with reporting error will help to evaluate the feasibility 
of conducting surveys on family history of cancer.
    Frequency of Response: One-time study.
    Affected Public: Individuals or households.
    Type of Respondent: Adults, age 25 to 64, who reside in the state 
of Connecticut and their selected adult relatives over age 25 or the 
relative's next-of-kin. The annual reporting burden is presented in the 
table below. The annualized cost to respondents is estimated at 
$18,671. There are no capital costs to report. There are no Operating 
or Maintenance Costs to report.

----------------------------------------------------------------------------------------------------------------
                                                                   Estimated No.                     Estimated
                                                   Estimated No.   of responses   Average burden   total annual
               Type of respondents                of respondents        per          hours per     burden hours
                                                                    respondent       response        requested
----------------------------------------------------------------------------------------------------------------
Respondents, age 25 to 64.......................            1800               1          0.6179            1112
Adult relatives of respondents or their next-of-            5190            0.67          0.2171             755
 kin............................................
                                                 ---------------------------------------------------------------
    Total.......................................  ..............  ..............  ..............            1867
----------------------------------------------------------------------------------------------------------------

Request for Comments

    Written comments and/or suggestions from the public and affected 
agencies are invited on one or more of the following points: (1) 
Whether the proposed collection of information is necessary for the 
proper performance of the function of the agency, including whether the 
information will have practical utility; (2) The accuracy of the 
agency's estimate of the burden of the proposed collection of 
information, including the validity of the methodology and assumptions 
used; (3) Ways to enhance the quality, utility, and clarity of the 
information to be collected; and (4) Ways to minimize the burden of the 
collection of information on those who are to respond, including the 
use of appropriate automated, electronic, mechanical, or other 
technological collection techniques or other forms of information 
technology.

Direct Comments to OMB

    Written comments and/or suggestions regarding the items(s) 
contained in this notice, especially regarding the estimated public 
burden and associated response time, should be directed to the: Office 
of Management and Budget, Office of Regulatory Affairs, New Executive 
Office Building, Room 10235, Washington, DC 20503, Attention: Desk 
Officer for NIH. To request more information on the proposed project or 
to obtain a copy of the data collection plans and instruments, contact: 
Dr. Louise Wideroff, Project Officer, Applied Research Program, 
National Cancer Institutes, 6130 Executive Blvd, EPN 4010, Bethesda, MD 
20892, or call non-toll-free number (301) 435-6823 or E-mail your 
request, including your address to [email protected].

COMMENTS DUE DATE: Comments regarding this information collection are 
best assured of having their full effect if received before January 18, 
2001.

    Dated: December 7, 2000.
Reesa Nichols,
NCI Project Clearance Liaison.
[FR Doc. 00-32234 Filed 12-18-00; 8:45 am]
BILLING CODE 4140-01-M