[Federal Register Volume 65, Number 165 (Thursday, August 24, 2000)]
[Notices]
[Page 51594]
From the Federal Register Online via the Government Publishing Office [www.gpo.gov]
[FR Doc No: 00-21655]


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DEPARTMENT OF DEFENSE

Department of the Army


Availability for Non-Exclusive, Exclusive, or Partially Exclusive 
Licensing of U.S. Patent Application Concerning Overcoming Interference 
in Alphavirus Immune Individuals

AGENCY: U.S. Army Medical Research and Materiel Command, DoD.

ACTION: Notice.

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SUMMARY: In accordance with 37 CFR 404.6, announcement is made of the 
availability for licensing of U.S. Patent Application Serial Number 09/
082,357 entitled ``Overcoming Interference in Alphavirus Immune 
Individuals'', filed May 20, 1998. This patent has been assigned to the 
United States Government as represented by the Secretary of the Army.

ADDRESSES: Commander, U.S. Army Medical Research and Materiel Command, 
ATTN: Command Judge Advocate, MCMR-JA, 504 Scott Street, Fort Detrick, 
Frederick, Maryland 21702-5012.

FOR FURTHER INFORMATION CONTACT: For patent issues, Ms. Elizabeth 
Arwine, Patent Attorney, (301) 619-7808. For licensing issues, Dr. Paul 
Mele, Office of Research & Technology Assessment, (301) 619-6664. Both 
at telefax (301) 619-5034.

SUPPLEMENTARY INFORMATION: This invention is a method for overcoming 
alphavirus vaccine interference in alphavirus-immune subjects by 
administration of a second alphavirus vaccine which is altered such 
that it is not accessible to interfering antibodies. Examples of such 
alterations are described as well as evidence showing that alphavirus 
interference likely results from the binding of interfering antibodies 
to viral proteins expressed on infected cells thereby causing lysis of 
infected cells.

Gregory D. Showalter,
Army Federal Register Liaison Officer.
[FR Doc. 00-21655 Filed 8-23-00; 8:45 am]
BILLING CODE 3710-08-U