[Federal Register Volume 65, Number 114 (Tuesday, June 13, 2000)]
[Notices]
[Pages 37149-37153]
From the Federal Register Online via the Government Publishing Office [www.gpo.gov]
[FR Doc No: 00-14831]


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DEPARTMENT OF HEALTH AND HUMAN SERVICES

Centers for Disease Control and Prevention

[Program Announcement 01007]


Grants for Injury Control Research Centers; Notice of 
Availability of Funds

A. Purpose

    The Centers for Disease Control and Prevention (CDC) announces the 
availability of fiscal year (FY) 2001 funds for Injury Control Research 
Center (ICRC) grants. This program addresses the ``Healthy People 
2010'' priority areas of Injury Prevention, Unintentional Injury 
Prevention, and Violence and Abuse Prevention. For the conference copy 
of ``Healthy People 2010,'' visit the Internet site: http://www.health.gov/healthypeople.
    The purposes of this program are:
    1. To support injury prevention and control research on priority 
issues as delineated in: Healthy People 2010; Injury Control in the 
1990's: A National Plan for Action; Reducing the Burden of Injury: 
Advancing Prevention and Treatment; Injury in America; Injury 
Prevention: Meeting the Challenge; Cost of Injury: A Report to the 
Congress; and any list of research priorities published by the National 
Center for Injury Prevention and Control (NCIPC);
    2. To integrate, in the context of a national program, the 
disciplines of engineering, epidemiology, medicine, biostatistics, 
public health, law and criminal justice, and behavioral and social 
sciences in order to prevent and control injuries more effectively;
    3. To support the identification and description of injury 
problems, to identify risk and protective factors that can be used to 
design and test injury prevention and control strategies, to evaluate 
current and new interventions for the prevention and control of 
injuries, and to support the implementation of effective prevention and 
control strategies in the public and private sector; and
    4. To provide technical assistance to injury prevention and control 
programs within a geographic region.

B. Eligible Applicants

    This announcement will provide funding for applicants in regions 
which do not have funded Injury Control Research Centers (ICRCs) and 
for applicants in regions which have funded centers which must re-
compete for funding.
    Eligible applicants include all nonprofit and for-profit 
organizations in

[[Page 37150]]

Regions 1, 2, 5, 6, 7, 8, and 9. Thus, universities, colleges, research 
institutions, hospitals, other public and private organizations, State 
and local health departments, and small, minority and/or women-owned 
businesses are eligible for these grants. Non-academic applicant 
institutions should provide evidence of a collaborative relationship 
with an academic institution.
    Eligible applicants are limited to organizations in Region 1 
(Connecticut, Maine, Massachusetts, New Hampshire, Rhode Island, and 
Vermont), Region 2 (New Jersey, New York, Puerto Rico, and Virgin 
Islands), Region 5 (Illinois, Indiana, Michigan, Minnesota, Ohio, and 
Wisconsin), Region 6 (Arkansas, Louisiana, New Mexico, Oklahoma, and 
Texas), Region 7 (Iowa, Kansas, Missouri, and Nebraska), Region 8 
(Colorado, Montana, North Dakota, South Dakota, Utah, and Wyoming), and 
Region 9 (Arizona, California, Hawaii, Nevada, American Samoa, Guam, 
Mariana Islands, Marshall Islands, Micronesia, and Palau).

    Note:
    ICRC grant awards are made to the applicant institution/
organization, not the Principal Investigator.


    Note:
    Public Law 104-65 states that an organization described in 
section 501(c)(4) of the Internal Revenue Code of 1986 that engages 
in lobbying activities is not eligible to receive Federal funds 
constituting an award, grant, cooperative agreement, contract, loan, 
or any other form.

C. Availability of Funds

    Approximately $3,622,000 is expected to be available in FY 2001 to 
fund approximately four awards. It is expected that the average award 
will be $905,500 (total of direct and indirect costs). It is expected 
that the awards will begin on or around September 1, 2001, and will be 
made for a 12 month budget period within a project period of up to five 
years. Applications that exceed the funding cap of $905,500 will be 
excluded from the competition and returned to the applicant. Funding 
estimates may change. Continuation awards within an approved project 
period will be made on the basis of satisfactory progress as evidenced 
by required reports and the availability of funds.

Use of Funds

    Center funding is to be designated for two types of activities. One 
type of activity is considered ``Core'' and includes administration, 
management, general support services (e.g. statistical, library, media 
relations, and advocacy) as well as activities associated with research 
development, technical assistance, and education (e.g. seed projects, 
training activities, and collaborative and technical assistance 
activities with other groups). Funds may be allocated for trainee 
stipends, tuition remission, and trainee travel, in accordance with the 
current rates for the Public Health agencies. Indirect costs for these 
trainee-related activities are limited to 8.0 percent. Defined research 
projects constitute the second type of activity, and ICRCs are 
encouraged to work toward addressing the breadth of the field. Core 
activities and defined research projects may each constitute between 25 
percent-75 percent of the operating budget and should be balanced in 
such a way that the ICRC demonstrates productivity in research as well 
as teaching and service. Applicants with less demonstrated expertise in 
research are encouraged to devote a larger percentage of funds to 
defined research projects in order to establish their capability as 
research centers of excellence.
    Grant funds will not be made available to support the provision of 
direct care. Studies may be supported which evaluate methods of care 
and rehabilitation for potential reductions in injury effects and 
costs. Studies can be supported which identify the effect on injury 
outcomes and cost of systems for pre-hospital, hospital, and 
rehabilitative care and independent living.
    Eligible applicants may enter into contracts, including consortia 
agreements (as set forth in the PHS Grants Policy Statement, dated 
April 1, 1994), as necessary to meet the requirements of the program 
and strengthen the overall application.

Funding Preferences

    Funding preference will be given to re-competing ICRCs. These 
centers represent a long term investment for NCIPC and an established 
resource for Injury Control related issues for their States and 
regions.

D. Program Requirements

    The following are applicant requirements:
    1. Applicants must demonstrate expertise and conduct research 
projects in at least one of the three phases of injury control 
(prevention, acute care, or rehabilitation) and are encouraged to be 
comprehensive.
    2. Applicants must document ongoing injury-related research 
projects or control activities currently supported by other sources of 
funding.
    3. Applicants must provide a director (Principal Investigator) who 
has specific authority and responsibility to carry out the project. The 
director must report to an appropriate institutional official, e.g., 
dean of a school, vice president of a university, or commissioner of 
health. The director must have no less than 30 percent effort devoted 
solely to this project with an anticipated range of 30 percent--50 
percent.
    4. Applicants must demonstrate experience in successfully 
conducting, evaluating, and publishing injury research and/or 
designing, implementing, and evaluating injury control programs.
    5. Applicants must provide evidence of working relationships with 
outside agencies and other entities which will allow for implementation 
of any proposed intervention activities.
    6. Applicants must provide evidence of involvement of specialists 
or experts in medicine, engineering, epidemiology, law and criminal 
justice, behavioral and social sciences, biostatistics, and/or public 
health as needed to complete the plans of the center. These are 
considered the disciplines and fields for ICRCs. An ICRC is encouraged 
to involve biomechanicists in its research. This, again, may be 
achieved through collaborative relationships as it is not a requirement 
that all ICRCs have biomechanical engineering expertise.
    7. Applicants must have established curricula and graduate training 
programs in disciplines relevant to injury control (e.g., epidemiology, 
biomechanics, safety engineering, traffic safety, behavioral sciences, 
or economics).
    8. Applicants must demonstrate the ability to disseminate injury 
control research findings, translate them into interventions, and 
evaluate their effectiveness.
    9. Applicants must have an established relationship, demonstrated 
by letters of agreement, with injury prevention and control programs or 
injury surveillance programs being carried out in the region in which 
the ICRC is located. Cooperation with private-sector programs, e.g. 
``Safe USA'' partnerships, is encouraged.
    10. Applicants should have an established or documented planned 
relationship with organizations or individual leaders in communities 
where injuries occur at high rates, e.g., minority communities.

E. Application Content

    Use the information in the Program Requirements, Other 
Requirements, and Evaluation Criteria sections to develop the 
application content. Applications should include the following 
information:
    1. Face page
    2. Description (abstract) and personnel

[[Page 37151]]

    3. Table of contents
    4. Detailed budget for the initial budget period: The budget should 
reflect the composite figures for the grant. In addition, separate 
budgets (direct and indirect costs) and justifications should be 
provided for the following categories of activities:
    a. Core activities, including management and administrative 
functions, other non-research activities (e.g. education/training, 
consultation, technical assistance, translation/dissemination, program 
and policy development and evaluation, advocacy, and media activities, 
etc.), and small seed projects of less than $15,000 for a one year 
period or less.
    b. Research Studies:
    (1) Small studies of $15,000-75,000 for each, of one to three years 
duration. These projects might be expansions of seed projects, either 
further developing methods or hypotheses in preparation for a larger 
investigation leading to the submission of an RO1 level proposal, or 
may be stand-alone investigations sufficient to yield results worthy of 
publication in a peer-reviewed journal and/or a technical report for a 
legislative body, governmental agency, or injury control program.
    (2) Larger scale studies with annual budgets exceeding $75,000 and 
lasting up to five years. These projects typically will test hypotheses 
and employ more sophisticated methodologies and/or larger sample sizes 
than small studies.
    For seed projects, only modest descriptions are required within the 
application and/or clear definition of procedures used to select the 
projects. More detailed descriptions, commensurate with costs, are 
required for both small studies and larger scale projects.
    5. Budget for entire proposed project period including budgets 
pertaining to consortium/contractual arrangements.
    6. Biographical sketches of key personnel, consultants, and 
collaborators, beginning with the Principal Investigator and core 
faculty.
    7. Other support: This listing should include all other funds or 
resources pending or currently available. For each grant or contract 
include source of funds, amount of funding (indicate whether pending or 
current), date of funding (initiation and termination), and 
relationship to the proposed program.
    8. Resources and environment.
    9. Research plan:
    a. ICRCs are to develop a range of research and other non-research 
activities that are designed to advance the field of injury control 
through development of new scientific or surveillance methods, creation 
of new knowledge, and translation of knowledge into training, program 
and policy development and evaluation activities or other applications 
that will ultimately reduce injuries or their effects. ICRC 
applications should articulate how the activities of their program are 
integrated with each other so as to demonstrate the whole of the ICRCs 
activities and their potential impact.
    b. A detailed research plan (design and methods) including 
hypothesis and expected outcome, value to field, and specific, 
measurable, and time-framed objectives consistent with the activities 
for each project within the proposed grant.
    (1) Seed projects require a short write up describing the injury 
control context of the study, the objective, the design, the setting 
and participants, the intervention being addressed, main outcome 
measurements, expected results, time lines, cost (direct and indirect), 
and plans for translation/dissemination, and/or clear definition of 
procedures used to select the projects.
    (2) Small research projects require a 10-15 page write up 
describing the accomplishment of all the steps, including the 
development and testing of methods, the instruments, and the collection 
of preliminary data, needed to take an innovative approach and develop 
it to the level of a larger investigation leading to the submission of 
an RO1 level proposal or a stand-alone investigation sufficient to 
yield results worthy of publication in a peer-reviewed journal and/or a 
technical report for a legislative body, governmental agency, or injury 
control program.
    (3) Large research projects require an RO1 level write up as 
described in the PHS 398 (Rev. 4/98) guidelines and should be included 
as appendices of the application.
    (4) A detailed evaluation plan which should address outcome and 
cost-effectiveness evaluations as well as formative, efficacy, and 
process evaluation.
    Include in the narrative for each small research project and large 
project in the research plan section of the application:
    (1) Title of Project
    (2) Project Director/Lead Investigator
    (3) Institution(s)
    (4) Categorization as to ``Prevention, Acute Care, Rehabilitation, 
or Biomechanics''
    (5) Categorization as to ``Seed Project, Small Project, or Large 
Project''
    (6) Categorization as to ``New or Ongoing Project''
    (7) Cost/Year (Direct and Indirect)
    (8) Research Training? Names, Degrees of Persons Trained or in 
Training
    (9) Key Words
    (10) Brief Summary of Project including Intended Application of 
Finding (Abstract)
    c. A description of the core faculty and its role in implementing 
and evaluating the proposed programs. The applicant should clearly 
specify how disciplines will be integrated to achieve the ICRCs 
objectives.
    d. Charts showing the proposed organizational structure of the ICRC 
and its relationship to the broader institution of which it is a part, 
and, where applicable, to affiliate institutions or collaborating 
organizations. These charts should clearly detail the lines of 
authority as they relate to the center or the project, both 
structurally and operationally. ICRC directors should report to an 
appropriate organizational level (e.g. dean of a school, vice president 
of a university, or commissioner of health), demonstrating strong 
institution-wide support of ICRC activities and ensuring oversight of 
the process of interdisciplinary activity.
    e. Documentation of the involved public health agencies and other 
public and private sector entities to be involved in the proposed 
program, including letters that detail commitments of support and a 
clear statement of the role, activities, and participating personnel of 
each agency or entity.
    An applicant organization has the option of having specific salary 
and fringe benefit amounts for individuals omitted from the copies of 
the application which are made available to outside reviewing groups. 
To exercise this option: on the original and five copies of the 
application, the applicant must use asterisks to indicate those 
individuals for whom salaries and fringe benefits are not shown; the 
subtotals must still be shown. In addition, the applicant must submit 
an additional copy of page four of Form PHS-398, completed in full, 
with the asterisks replaced by the salaries and fringe benefits. This 
budget page will be reserved for internal staff use only.

F. Submission and Deadline

    Submit the original and five copies of PHS 398 (OMB Number 0925-
0001)and adhere to the instructions on the Errata Instruction sheet for 
PHS 398). Forms are in the application kit.
    On or before November 1, 2000, submit the application to the Grants 
Management Specialist identified in the Where to Obtain Additional 
Information section of this announcement.

[[Page 37152]]

    Applications shall be considered as meeting the deadline if they 
are either:
    1. Received on or before the deadline date; or
    2. Sent on or before the deadline date and received in time for 
submission to the independent review group. Applicants must request a 
legibly dated U.S. Postal Service postmark or obtain a legibly dated 
receipt from a commercial carrier or the U.S. Postal Service. Private 
metered postmarks shall not be acceptable as proof of timely mailing.
    Late Applications: Applications which do not meet the criteria in 
(1.) or (2.) above are considered late applications, will not be 
considered, and will be returned to the applicant.

G. Evaluation Criteria

    Upon receipt, applications will be reviewed by CDC staff for 
completeness and responsiveness as outlined under the previous heading 
Program Requirements. Incomplete applications and applications that are 
not responsive will be returned to the applicant without further 
consideration.
    Applications which are complete and responsive may be subjected to 
a preliminary evaluation (triage) by the Injury Research Grant Review 
Committee (IRGRC) to determine if the application is of sufficient 
technical and scientific merit to warrant further review by the IRGRC. 
CDC will withdraw from further consideration applications judged to be 
noncompetitive and promptly notify the principal investigator/program 
director and the official signing for the applicant organization. Those 
applications judged to be competitive will be further evaluated by a 
dual review process.
    Awards will be made based on priority scores assigned to 
applications by the IRGRC, programmatic priorities and needs determined 
by a secondary review committee (the Advisory Committee for Injury 
Prevention and Control), and the availability of funds.

1. Review by the Injury Research Grants Review Committee (IRGRC)

    Initial peer review of ICRC grant applications will be conducted by 
the IRGRC, which will recommend the application for further 
consideration or not for further consideration. For those applications 
recommended for further consideration, a team of peer reviewers, 
including members of the IRGRC, will conduct on-site visits at each 
applicant institution, generate summary statements for the visits, and 
report its assessment to the IRGRC.
    Factors to be considered by the IRGRC include:
    a. The specific aims of the application, e.g., the long-term 
objectives and intended accomplishments. Approval of research projects 
(including new research projects proposed during the five year funding 
cycle) is subject to peer review.
    (1) Seed projects will be evaluated collectively on the mechanism 
for solicitation of projects, on the technical/scientific merit review, 
and on the selection and monitoring of projects.
    (2) Small projects will be evaluated individually on the innovative 
approach and proposed methods for achieving an investigation sufficient 
to support a submission of an RO1 level proposal and/or worthy of 
publication in a peer-reviewed journal and/or a technical report for a 
legislative body, governmental agency, or injury control program.
    (3) Large projects will be evaluated individually according to 
existing RO1 level project standards as described in the PHS 398 (Rev. 
4/98) guidelines. An application must have a minimum of three large 
research projects approved in order to be recommended for further 
consideration.
    b. The scientific and technical merit of the overall application, 
including the significance and originality (e.g., new topic, new 
method, new approach in a new population, or advancing understanding of 
the problem) of the proposed research.
    c. The extent to which the evaluation plan will allow for the 
measurement of progress toward the achievement of stated application 
objectives.
    d. Qualifications, adequacy, and appropriateness of personnel to 
accomplish the proposed activities.
    e. The soundness of the proposed budget in terms of adequacy of 
resources and their allocation.
    f. In addition to conducting defined research projects, ICRCs are 
expected to devote substantial attention to activities directed at 
advancing the field through other activities that are designed to 
improve research capabilities and translate research into practice. 
Examples of such activities include consultation and technical 
assistance that are responsive to regional and state priorities, 
professional training for researchers and practitioners, program 
development, and evaluation endeavors. The degree of effort devoted to 
these aspects of an ICRCs program should be clearly stated in the 
justification and the budget. The degree of effort may be varied and 
should reflect the specific focus and goals of the ICRC.
    g. Details of progress in the most recent funding period should be 
provided in the application if the applicant is submitting a re-
competing application. Documented examples of success include: 
development of pilot projects; completion of high quality research 
projects; publication of findings in peer reviewed scientific and 
technical journals; number of professionals trained; ongoing provision 
of consultation and technical assistance; integration of disciplines; 
translation of research into implementation; impact on injury control 
outcomes including legislation, regulation, treatment, and behavior 
modification interventions.
    h. Does the application adequately address the requirements of 
Title 45 CFR Part 46 for the protection of human subjects?
    i. Does the applicant meet the CDC Policy requirements regarding 
the inclusion of women, ethnic, and racial groups in the proposed 
research?
    j. Does the application adequately address the requirements of the 
``PHS Policy on Humane Care and Use of Laboratory Animals by Awardee 
Institutions?'

2. Review by the CDC Advisory Committee for Injury Prevention and 
Control (ACIPC)

    Secondary review of ICRC grant applications will be conducted by 
the Science and Program Review Work Group (SPRWG) of the ACIPC. The 
SPRWG consists of ACIPC members, Federal ex officio participants, and 
organizational liaisons. The Federal ex officio participants will be 
responsible for identifying proposals in overlapping areas of research 
interest so that unwarranted duplication in federally-funded research 
can be avoided. The NCIPC Division Associate Directors for Science 
(ADS) or their designees will address the SPRWG to assure that research 
priorities of the announcement are understood and to provide background 
regarding current research activities. These recommendations will be 
presented to the entire ACIPC in the form of a report by the Chairman 
of the SPRWG. The ACIPC will vote to approve, disapprove, or modify 
these recommendations for funding consideration.
    These recommendations, based on the results of the review by the 
IRGRC, the relevance and balance of the proposed research relative to 
the NCIPC programs and priorities, and the assurance of no duplication 
of federally-funded research, are presented to the Director, NCIPC, for 
funding decisions.
    Factors to be considered by the ACIPC include:
    a. The results of the peer review.
    b. The significance of the proposed activities as they relate to 
national

[[Page 37153]]

program priorities, geographic balance, and the achievement of national 
objectives.
    c. The overall balance of the ICRC program in addressing the three 
phases of injury control (prevention, acute care, and rehabilitation); 
the control of injury among populations who are at increased risk, 
including racial/ethnic minority groups, the elderly and children; the 
major causes of intentional and unintentional injury; and the major 
disciplines of injury control (such as biomechanics, epidemiology, and 
behavioral science).
    d. Budgetary considerations. The ACIPC will recommend annual 
funding levels as detailed under the heading, Availability of Funds.

3. Continued Funding

    Continuation awards within the project period will be made on the 
basis of the availability of funds and the following criteria:
    a. The accomplishments of the current budget period show that the 
applicant's objectives as prescribed in the yearly work plans are being 
met;
    b. The objectives for the new budget period are realistic, 
specific, and measurable;
    c. The methods described will clearly lead to achievement of these 
objectives;
    d. The evaluation plan allows management to monitor whether the 
methods are effective by having clearly defined process, impact, and 
outcome objectives, and the applicant demonstrates progress in 
implementing the evaluation plan; and
    e. The budget request is clearly explained, adequately justified, 
reasonable, and consistent with the intended use of grant funds.

H. Other Requirements

Technical Reporting Requirements

    Provide CDC with original plus two copies of
    1. progress report annually;
    2. financial status report, no more than 90 days after the end of 
the budget period; and
    3. final financial status report and performance report, no more 
than 90 days after the end of the project period.
    Send all reports to the Grants Management Specialist identified in 
the Where to Obtain Additional Information section of this 
announcement.
    The following additional requirements are applicable to this 
program. For a complete description of each see Addendum 1 in the 
application kit.

AR-1  Human Subjects Certification
AR-2  Requirements for inclusion of Women and Racial and Ethnic 
Minorities in Research
AR-3  Animal Subjects Requirements
AR-9  Paperwork Reduction Act Requirements
AR-10   Smoke-Free Workplace Requirement
AR-11  Healthy People 2010
AR-12  Lobbying Restrictions
AR-13  Prohibition on Use of CDC funds for Certain Gun Control 
Activities
AR-20  Conference Activities within Grants/Cooperative Agreements

I. Authority and Catalog of Federal Domestic Assistance Number

    This program is authorized under Sections 301, 391, 392, 393, and 
394 of the Public Health Service Act, [42 U.S.C. 241, 280b, 280b-1, 
280b-1a, and 280b-2] as amended. Catalog of Federal Domestic Assistance 
number is 93.136.

J. Where To Obtain Additional Information

    For this announcement and other CDC announcements, see the CDC home 
page on the Internet: http://www.cdc.gov.
    To receive additional written information and to request an 
application kit, call 1-888-GRANTS4 (1-888-472-6874). You will be asked 
to leave your name and address and will be instructed to identify the 
Announcement number of interest. A complete program description and 
information on application procedures are contained in the application 
package.
    If you have questions after reviewing the contents of all the 
documents, business management assistance may be obtained from: Joanne 
Wojcik, Grants Management Specialist, Grants Management Branch, 
Procurement and Grants Office, Centers for Disease Control and 
Prevention (CDC), Colgate Building, Room 3000, 2920 Brandywine Road, 
Atlanta, GA 30341-4146, Telephone 770-488-2717, Internet address: 
[email protected]
    Programmatic assistance may be obtained from: Tom Voglesonger, 
Program Manager, Office of Research Grants, National Center for Injury 
Prevention and Control, Centers for Disease Control and Prevention 
(CDC), 4770 Buford Highway, NE., (K58), Atlanta, GA 30341-3724, 
Telephone 770-488-4265, Internet address: [email protected].
    Please refer to Announcement 01007 when requesting information and 
submitting an application.

    Dated: June 7, 2000.
Henry S. Cassell, III,
Acting Director, Procurement and Grants Office, Centers for Disease 
Control and Prevention (CDC).
[FR Doc. 00-14831 Filed 6-12-00; 8:45 am]
BILLING CODE 4163-18-P