[Federal Register Volume 65, Number 74 (Monday, April 17, 2000)]
[Notices]
[Pages 20466-20469]
From the Federal Register Online via the Government Publishing Office [www.gpo.gov]
[FR Doc No: 00-9455]


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DEPARTMENT OF HEALTH AND HUMAN SERVICES

Centers for Disease Control and Prevention

[Program Announcement 00089]


Health Promotion and Disease Prevention Research Center 
Cooperative Agreement; Notice of Availability of Funds

A. Purpose

    The Centers for Disease Control and Prevention (CDC) announces the 
availability of fiscal year (FY) 2000 funds for a cooperative agreement 
program to fund a Health Promotion and Disease Prevention Research 
Center (PRC) at the University of Kentucky. CDC is committed to 
achieving the health promotion and disease prevention objectives of 
``Healthy People 2010,'' a national activity to reduce morbidity and 
mortality and improve the quality of life. This announcement is related 
to the focus area of Educational and Community-Based Programs. For the 
conference copy of ``Healthy People 2010'', visit the internet site 
http://www.health.gov/healthypeople. The purpose of the program is to 
support health promotion and disease prevention research that focuses 
on the major causes of death and disability and promote health 
practices that lead to more effective State and local programs.

    Note: Background and CDC program objectives are provided in 
Attachment 1.

B. Eligible Applicants

    Assistance will be provided only to the University of Kentucky, 
School of Medicine. No other applications are solicited.

C. Availability of Funds

    Approximately $525,000 is available in FY 2000 to fund a Health 
Promotion and Disease Prevention Research Center in Kentucky. It is 
expected that the award will begin on or about September 30, 2000, and 
will be made for a 12-month budget period within a project period of up 
to three years. Funding estimates may change. Continuation awards 
within an approved project period will be made on the basis of 
satisfactory progress as evidenced by required reports and the 
availability of funds.

Direct Assistance

    You may request Federal personnel, equipment, or supplies as direct 
assistance, in lieu of a portion of financial assistance (see 
Application Content).

D. Program Requirements

    In conducting activities to achieve the purpose of this program, 
the recipient will be responsible for the activities under 1. 
(Recipient Activities), and CDC will be responsible for the activities 
under 2. (CDC Activities).

1. Recipient Activities

    a. Select a research theme that will serve as a focus for 
Prevention Research activities for Appalachia.
    b. Develop the administrative structure and recruit staff to 
implement a Prevention Research Center plan.
    c. Conduct and evaluate a demonstration project in health promotion 
and disease prevention or preventive health services, within a defined 
community or special population. The project must reflect the needs of 
the community within the applicant's jurisdiction and show evidence of 
having used an appropriate planning process in determining project 
selection. Consistent with the discussion in the Background and CDC 
Program Objectives (See Attachment 1), the project should specify how 
the research project will heighten public health practice and advance 
research translation.
    d. Establish an advisory committee to provide input on the major 
program activities. Membership may include but is not limited to a 
variety of local health-care providers, health and education agency 
officials, community leaders and organizers, and representatives of 
local businesses, churches, voluntary organizations, and consumers.
    e. Establish collaborative activities with appropriate 
organizations, individuals, and State and local health departments.
    f. Conduct applied community-based training in research methods to 
foster community involvement and build community capacity for 
participatory research. If appropriate, this training may include a 
distance-learning-based format.
    g. Establish the capacity to implement and evaluate multi 
disciplinary, professional training programs in prevention research.
    h. Establish a plan to ensure translation of results to appropriate 
constituencies.

2. CDC Activities

    a. Collaborate as appropriate with the recipient in all stages of 
the project.
    b. Provide programmatic and technical assistance.
    c. Participate in improving program performance through 
consultation based on information and activities of other projects.
    d. Provide scientific collaboration with grantee as necessary to 
meet program goals and objectives.
    e. At the request of the applicant, assist with developing the 
curriculum, training, or conducting other specific necessary 
activities.

E. Application Content

Application

    Use the information in the Program Requirements, Other 
Requirements, and Evaluation Criteria sections to develop the 
application content. The application will be evaluated on the criteria 
listed, so it is important to follow them in laying out the program 
plan. The narrative must not exceed 90 double-spaced pages, printed on 
one side, with one inch margins, and 12'' font, excluding appendixes 
and PHS Form 398. Appendices must not exceed 25 pages and must be hard 
copy documents (i.e., no audiovisual materials, posters, etc.).
1. Research Theme
    Identify a research theme and describe activities designed to focus 
on the theme that will result in innovative approaches to prevention 
research. Clearly identify the need of the partner community in 
Appalachia, and describe the PRC's experience working with communities 
on the identified research theme. The applicant may wish to refer to 
products from the Task Force Community Preventive Services when 
considering their research theme. (For detailed information, visit the 
Guide to Community Preventive Services on the Web at http://web.health.gov/communityguide). Examples of research themes from 
current Research Prevention Centers include:

[[Page 20467]]

    a. Bridging the Gap Between Public Health Science and Practice in 
Underserved Populations.
    b. Promoting the Health of Multiethnic Communities of the 
Southwest.
    c. Putting Health Promotion into Action Community Collaboration.
    d. Reduction of Excess Morbidity and Mortality in the Harlem 
Community.
    e. Promoting Healthy Behavior and Disease Prevention in Native 
American Populations.
2. Prevention Research Center Plan
    Submit a plan for a prevention research center serving Appalachia 
with clear goals, objectives, and activities, to include:
    a. A description of goals and objectives for the budget period that 
are consistent with the research theme. Objectives should be specific, 
measurable, attainable, realistic and time-phased (SMART MODEL for 
objectives).
    b. A description of the scope, methods of operation, evaluation, 
and a timeline for implementation.
    c. A description of the use of other federal funds that will impact 
on stated program objectives.
    d. A description of any financial and in-kind contributions from 
nonfederal sources.
    e. Documentation describing the composition, membership, rationale 
for membership, and objectives for a Community Advisory Committee. 
Documentation of how the Advisory Committee will facilitate 
collaboration with community organizations, State and local health or 
education departments.
    f. A description of plans for conducting community-based applied 
training.
    g. A description of capacity to provide prevention research 
training for professionals.
    h. Documentation of commitment to minority and underserved 
populations, or other defined populations or communities.
    i. A description of significant factors which may favorably or 
adversely impact on program performance.
3. Management and Staffing Plan
    Provide a management plan that includes a description of all 
organizational units and functions in the PRC. The plan should reflect 
the ability of the PRC to carry out the chosen research theme. Describe 
how the applicant will integrate the PRC within the parent institution. 
The following areas should be considered in developing a management and 
staffing plan:
    a. Describe the PRCs personnel infrastructure.
    b. Describe how proposed staffing will support center activity. 
Current resumes must be included.
    c. Describe how the proposed staff meet the goal of establishing 
multidisciplinary prevention research centers.
    d. No less than two full-time positions (FTE's) must be allocated 
for the following functions: (Percentages of an FTE may be used for 
several positions.)
    (1) Scientific oversight: Accountable for center research and 
development, design, methodology, project evaluation, and publications.
    (2) Community Development: Community liaison, advisory committee, 
community training activities, and community dissemination.
    (3) Program and Project Management: Oversight of center supported 
research and Institutional Review Board (IRB) protocols, coordination 
of center studies, mentorship of junior investigators, dissemination 
activities, and professional training in prevention research.
    (4) Center Administration: Responsible for communication with CDC's 
Prevention Research Centers Program staff and Procurement and Grants 
Office. Responsibilities will include submission of fiscal reports, 
fiscal tracking and reports, personnel, and center procurement.
4. Research Project
    Submit a description of a research project that is consistent with 
the CDC PRC Program objectives and selected PRC theme. The narrative 
for specific project should contain:
    a. A description of the research project including goals, 
objectives, timeline, research questions and target population.
    b. A description of the research methods including methods for 
participant recruitment, data collection, evaluation design, and data 
analysis.
    c. A description of the extent of community and other research 
collaborations in the proposed project.
    d. A description of project staff (number and types of positions).
    e. A project budget.
    f. A description of the plans to translate research findings into 
public health practice or policy.
    g. Does the application adequately address the requirements of 
Title 45 CFR part 46 for the protection of human subjects?
5. Evaluation Plan
    Describe and plan a methodology to evaluate PRC program and 
activities with regard to program progress and process; fulfillment of 
outcome objectives; impact, and community involvement; the PRCs 
community-based objectives; and any other indicators, such as cost-
benefit analyses. Specify staff responsible for the plan and their 
background and experience in evaluation research.
6. Budget Information
    Provide a line-item budget and narrative justification for all 
requested costs that are consistent with the goals, objectives, and 
proposed research activities, to include:
    a. Line-item breakdown and justification for all personnel, i.e., 
name, position title, annual salary, percentage of time and effort, and 
amount requested.
    b. Line-item breakdown and justification for all contracts and 
consultants, to include:
    (1) Name of contractor or consultant
    (2) Period of performance
    (3) Method of selection (e.g., competitive or sole source)
    (4) Scope of work
    (5) Method of accountability
    (6) Itemized budget
    c. Requests for direct assistance in the form of field assignees 
must also include the following:
    (1) The number of assignees requested.
    (2) A description of the position and proposed duties for each 
assignee.
    (3) Justification for request.
    (4) An organizational chart and the name of the intended 
supervisor.
    (5) The availability of career-enhancing training, education, and 
research experience opportunities for the assignee(s).
    (6) Assignee access to computer equipment for electronic 
communication between CDC headquarter's office and PRC.
    d. A brief three-year budget projection should be submitted that 
clearly separates and distinguishes direct from indirect costs.

F. Submission and Deadline

    Submit the original and five copies of the application PHS Form 398 
(OMB Number 0925-0001) (adhere to the instructions on the Errata 
Instruction Sheet for PHS 398). Forms are available at the following 
Internet address: www.cdc.gov/ . . . Forms, or in the application kit. 
The application must be submitted on or before June 15, 2000. Submit 
the application to the Grants Management Specialist identified in the 
``Where to Obtain Additional Information'' section of this 
announcement.

[[Page 20468]]

    Deadline: The application shall be considered as meeting the 
deadline above if it is either:
    (a) Received on or before the deadline date; or
    (b) Sent on or before the deadline date. (Applicant must request a 
legibly dated U.S. Postal Service postmark or obtain a legibly dated 
receipt from a commercial carrier or the U.S. Postal Service. Private 
metered postmarks shall not be acceptable as proof of timely mailing.)

G. Evaluation Criteria

    An external peer review panel will review the application using the 
following criteria:
    (1) PRC Theme; (2) Center Plan; (3) Management and Staffing Plan; 
(4) Research Project; and (5) Evaluation. The Budget and Human Subjects 
sections are reviewed but not scored. The review panel will score the 
application overall, based on a 1-5 scale (with increments of 0.1) with 
1=highest (best) and 5-lowest. The reviewers' scores are then averaged 
and multiplied by 100 to attain a priority score for the application. 
The review panel will also compile a summary and recommendations 
including the strengths and weaknesses of the application.

1. PRC Theme

    To what extent does the research theme meet health priorities and 
emerging public health needs of identified communities or special 
groups?

2. Center Plan

    (a) To what extent does the plan have objectives that are clear, 
specific, measurable, attainable, realistic and time-phased?
    (b) Does the plan make effective use of both PRC and community 
resources to advance the PRC theme?
    (c) Is the plan consistent with the PRC purpose, and does it 
include a three-year timeline?
    (d) Does the plan describe the composition of a Community Advisory 
Committee and rationale for its membership, relevance and feasibility 
of committee objectives and its role within the PRC?
    (e) Is a plan included to establish collaborative activities with 
appropriate organizations, individuals, State, and local health 
departments?
    (f) Is a plan included to conduct community-based training in 
research methods to foster community involvement and build community 
capacity for participatory research?
    (g) Does the plan contain a description of the Center's capacity 
for providing professional, multidisciplinary prevention research 
training in the area of health promotion and disease prevention?

3. Management and Staffing Plan

    To what extent does the applicant demonstrate the ability, 
capacity, organizational structure, and staffing to carry out the 
overall theme, objectives, and specific project plans?

4. Research Project

    (a) Does the applicant demonstrate an understanding of the 
community contexts, current scientific literature, as well as other 
information sources relevant to the proposed project?
    (b) Are the conceptual framework, design, methods, analyses, and 
translation plan adequately developed, well-integrated, scientifically 
strong, and appropriate to the aims of the project?
    (c) Does the proposed approach allow for flexibility or change in 
research methods or focus as necessary?
    (d) Does the applicant acknowledge potential problem areas and 
consider alternative tactics?
    (e) Is there an appropriate work plan included?
    (f) Does the project include plans to measure progress toward 
achieving the stated objectives?
    (g) Does the applicant propose research translation approaches or 
methods for findings from the project?
    (h) The degree to which the applicant has met the CDC policy 
requirements regarding the inclusion of women, ethnic and racial groups 
in the proposed research. This includes:
    (1) The proposed plan for the inclusion of both sexes and racial 
and ethnic minority populations for appropriate representation.
    (2) The proposed justification when representation is limited or 
absent.
    (3) A statement as to whether the design of the study is adequate 
to measure differences when warranted.
    (4) A statement as to whether the plans for recruitment and 
outreach for study participants include the process of establishing 
partnerships with community(ies) and recognition of mutual benefits.

5. Evaluation

    To what extent are the plan and methodology proposed to evaluate 
the PRC program and activities with regard to program progress and 
process; fulfillment of outcome objectives; impact, and community 
involvement; the PRCs community-based objectives; and any other 
indicators, such as cost-benefit analyses feasible and of scientific 
merit?

6. Budget (Reviewed But Not Scored)

    The extent to which the budget and justification are consistent 
with the program objectives and purpose.

7. Human Subjects (Reviewed But Not Scored)

    Does the application adequately address the requirements of Title 
45 CFR Part 46 for the protection of human subjects?

H. Other Requirements

Technical Reporting Requirements

    Provide CDC with original plus two copies of:
    1. progress reports (annual);
    2. financial status report, not more than 90 days after the end of 
the budget period; and
    3. final financial and performance reports, no more than 90 days 
after the end of the project period.
    Send all reports to the Grants Management Specialist identified in 
the ``Where to Obtain Additional Information'' section of this 
announcement.
    The following additional requirements are applicable to this 
program. For a complete description of each, see Attachment 2 in the 
application kit.

AR-1  Human Subjects Requirements
AR-2  Requirements for Inclusion of Women and Racial and Ethnic 
Minorities in Research
AR-7  Executive Order 12372 Review
AR-8  Public Health System Reporting Requirements
AR-9  Paperwork Reduction Act Requirements
AR-10  Smoke-Free Workplace Requirements
AR-11  Healthy People 2010
AR-12  Lobbying Restrictions

I. Authority and Catalog of Federal Domestic Assistance Number

    This program is authorized under sections 301(a), 317(k)(2) and 
1706 [42 U. S. C. 241(a), 247b(k)(2) and 300 u-5] of the Public Health 
Service Act, as amended. The Catalog of Federal Domestic Assistance 
number is 93.135.

J. Where To Obtain Additional Information

    To receive additional written information and to request an 
application kit, call 1-888-GRANTS4 (1-888-472-6874). You will be asked 
to leave your name and address and will be instructed to identify the 
Announcement number of interest.
    If you have questions after reviewing the contents of all the 
documents, business management/technical assistance may be obtained 
from: Robert

[[Page 20469]]

Hancock, Grants Management Specialist, Grants Management Branch, 
Procurement and Grants Office, Centers for Disease Control and 
Prevention (CDC), Room 3000, 2920 Brandywine Road, Atlanta, GA30341-
4146 telephone (770) 488-2746, E-mail address: [email protected]
    For program technical assistance, contact: Lynda Doll, Ph.D., 
Program Director, Prevention Research Centers Office, National Center 
for Chronic Disease Prevention and Health Promotion, Centers for 
Disease Control and Prevention (CDC), 4770 Buford Highway, NE, Atlanta, 
GA 30341-3724, telephone 404-488-5395, E-mail address: [email protected]

    Dated: April 11, 2000.
John L. Williams,
Director, Procurement and Grants Office.
[FR Doc. 00-9455 Filed 4-14-00; 8:45 am]
BILLING CODE 4163-18-P