[Federal Register Volume 65, Number 14 (Friday, January 21, 2000)]
[Notices]
[Pages 3465-3466]
From the Federal Register Online via the Government Publishing Office [www.gpo.gov]
[FR Doc No: 00-1422]


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DEPARTMENT OF HEALTH AND HUMAN SERVICES

National Institutes of Health


Proposed Data Collection; Comment Request; Clinical, Laboratory, 
and Epidemiologic Characterization of Individuals at High Risk of 
Cancer

SUMMARY:  In compliance with the requirement of Section 3506(c)(2)(A) 
of the Paperwork Reduction Act of 1995, for opportunity for public 
comment on proposed extension of existing data collection projects, the 
National Cancer Institute (NCI), the National Institutes of Health 
(NIH) will publish periodic summaries of proposed projects to be 
submitted to the Office of Management and Budget (OMB) for review and 
approval.

Proposed Collection

    Title: Clinical, Laboratory, and Epidemiologic Characterization of 
Individuals at High Risk of Cancer.
    Type of Information Collection Request: Extension of OMB No. 0925-
0194 (Expiration date 06/30/00).
    Need and Use of Information Collection: This ongoing research study 
will identify cancer-prone persons in order to learn about cancer risk 
and cancer causes in individuals and families. The primary objectives 
of this research study are to utilize clinical, laboratory, and 
epidemiologic approaches in studies of individuals and families at high 
risk of cancer to identify and further characterize cancer 
susceptibility factor. Respondents are members of families in which 
multiple cancers are thought to have occurred. Information about the 
occurrence of cancer is collected and reviewed to determine eligibility 
for further etiologic study. Participation is entirely voluntary. The 
findings will lead to a better understanding of the causes and risk 
factors for selected cancers, which may reduce cancer incidence, and 
promote the earlier diagnosis of some cancers.
    Frequency of Response: One time.
    Affected Public: Individuals or households.
    Type of Respondents: Adults.
    The annual reporting burden is as follows:
    Estimated Number of Respondents: 600 per year.
    Estimated Number of Responses per Respondent: 1.
    Average Burden Hours Per Response: 75.
    Estimated Total Annual Burden Hours Requested: 450.
    The annualized cost to respondents is estimated at: $4,500. There 
are no Capital Costs to report. There are no Operating or Maintenance 
Costs to report.

Request for Comments

    Written comments and/or suggestions from the public and affected 
agencies are invited on one or more of the following points: (1) 
Whether the proposed collection of information is necessary for the 
proper performance of the function of the agency, including whether the 
information will have practical utility; (2) the accuracy of the 
agency's estimates of the burden of the proposed collection of 
information, including the validity of the methodology and assumptions 
used; (3) ways to enhance the quality, utility, and clarity of the 
information to be collected; and (4) ways to minimize the burden of the 
collection of information on those who are to respond, including the 
use of appropriate automated, electronic, mechanical, or other 
technological collection techniques or other forms of information 
technology.

[[Page 3466]]


FOR FURTHER INFORMATION CONTACT:  To request more information on this 
project or to obtain a copy of the data collection plans and 
instrument, write to Dr. Margaret Tucker, Chief, Genetic Epidemiology 
Branch, National Cancer Institute, NIH, Executive Plaza South, Room 
7122, 6120 Executive Blvd., Bethesda, MD 20892, or call non-toll-free 
number (301) 496-4375, or E-mail your request, including your address 
to: [email protected].

Comments Due Date

    Comments regarding this information collection are best assured of 
having their full effect if received on or before 60 days from the date 
of this publication.

    Dated: January 12, 2000.
Reesa Nichols,
OMB Project Clearance Liaison.
[FR Doc. 00-1422 Filed 1-20-00; 8:45 am]
BILLING CODE 4140-01-M