[Federal Register Volume 64, Number 162 (Monday, August 23, 1999)]
[Notices]
[Pages 45970-45971]
From the Federal Register Online via the Government Publishing Office [www.gpo.gov]
[FR Doc No: 99-21776]


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DEPARTMENT OF HEALTH AND HUMAN SERVICES

Centers for Disease Control and Prevention
[30DAY-17-99]


Agency Forms Undergoing Paperwork Reduction Act Review

    The Centers for Disease Control and Prevention (CDC) publishes a 
list of information collection requests under review by the Office of 
Management and Budget (OMB) in compliance with the Paperwork Reduction 
Act (44 U.S.C. Chapter 35). To request a copy of these requests, call 
the CDC Reports Clearance Office on (404) 639-7090. Send written 
comments to CDC, Desk Officer; Human Resources and Housing Branch, New 
Executive Office Building, Room 10235; Washington, DC 20503. Written 
comments should be received within 30 days of this notice.

Proposed Projects

    1. The Tri-State Mining District: Lead Exposure and Immunotoxic 
Effects Study in the Tri-State District--New--The Agency for Toxic 
Substance and Disease Registry (ATSDR)--The proposed study evaluates 
associations between immune system dysfunction/ damage and exposure to 
lead among children in the Tri-State Mining District. This district 
encompasses several contaminated areas including three Superfund sites: 
The Oronogo-Duenweg Mining Belt site in Jasper County, Missouri; the 
Cherokee County Site in Kansas; and the Tar Creek, Ottawa County Site 
in Oklahoma.
    The proposed study consists of two repeated in-person interviews 
and biological testing for blood lead and immune function among 
participants of the ongoing lead screening programs in the Tri-State 
Mining district. Approximately 50 children identified as having blood 
lead >10 micrograms per deciliter and 50 children with blood lead 
levels <5 micrograms per deciliter will constitute the study and 
comparison groups respectively. Blood specimens will be obtained to 
measure lead, complete blood count, EP, ZPP, antibody titers, and the 
CDC/ATSDR recommended immune panel. A second blood drawn a month later 
will examine intra-personal immune tests stability and will help 
evaluate the relationship between immune results and recent illness. 
Parents will be interviewed using a children's health questionnaire 
that solicits information on demographics, the medical history of each 
child and the occurrences of recent illness. Statistical analyses will 
compare health outcome measures (symptoms, illness, change in immune 
parameters) to blood lead levels. Other than their time, there will be 
no cost to the respondents. The length of clearance requested is for 1 
year. Total annual burden hours are 125.

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                                                                                     No. of        Avg. burden/
                          Form name                                 No. of         responses/     response  (in
                                                                 respondents       respondent          hrs)
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Verification.................................................             500                1              0.5

[[Page 45971]]

 
Pediatric Immune Questionnaire...............................             100                2              0.5
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    Dated: August 17, 1999.
Nancy Cheal,
Acting Associate Director for Policy, Planning and Evaluation, Centers 
for Disease Control and Prevention (CDC).
[FR Doc. 99-21776 Filed 8-20-99; 8:45 am]
BILLING CODE 4163-18-P