[Federal Register Volume 64, Number 146 (Friday, July 30, 1999)]
[Notices]
[Page 41432]
From the Federal Register Online via the Government Publishing Office [www.gpo.gov]
[FR Doc No: 99-19499]


=======================================================================
-----------------------------------------------------------------------

DEPARTMENT OF HEALTH AND HUMAN SERVICES

Centers for Disease Control and Prevention


Government-Owned Inventions; Availability for Licensing

AGENCY: Centers for Disease Control and Prevention (CDC), Department of 
Health and Human Services (DHHS).

ACTION: Notice.

-----------------------------------------------------------------------

    The inventions named in this notice are owned by agencies of the 
United States Government and are available for licensing in the United 
States (U.S.) in accordance with 35 U.S.C. 207 to achieve expeditious 
commercialization of results of federally funded research and 
development. Foreign patent applications are filed on selected 
inventions to extend market coverage for U.S. companies and may also be 
available for licensing.

ADDRESSES: Licensing information and copies of the U.S. patent 
applications listed below may be obtained by writing to Thomas E. 
O'Toole, M.P.H., Deputy Director, Technology Transfer Office, Centers 
for Disease Control and Prevention (CDC), Mailstop E-67, 1600 Clifton 
Rd., Atlanta, GA 30333, telephone (404) 639-6266. Please note that a 
signed Confidential Disclosure Agreement will be required to receive 
copies of the patent application.

PCR and Serological Diagnosis Using the ARP Gene and Its Protein

    Methods for specific and highly sensitive detection of Treponema 
pallidum infection compromising the use of specific antigenic proteins 
and peptides unique to Treponema pallidum are provided. These methods 
are directed to the differential detection of specific Treponema 
infections enabling the identification of causative agents for specific 
Treponema disease states. Methods are particularly useful for detection 
of primary syphilis at early stages of infection.

Inventors: Hsi Liu et al.
U.S. Patent Application SN: not yet assigned.
(CDC Ref. #: I-040-98/0)

Method and Apparatus for Cough Sound Analysis

    This invention is a fast, simple, and reliable method and apparatus 
for recording cough sounds for diagnosing pulmonary disorders and 
diseases. Generated data can be used to diagnose pulmonary disorders 
and diseases as well as track the effectiveness of treatment regimens 
over time. The simple, noninvasive method allows screening of at-risk 
individuals and early detection of pulmonary disorders and diseases 
which may allow earlier treatment or environmental modification, 
reducing the risk of irreversible injury to pulmonary function.

Inventors: William Goldsmith et al.
U.S. Patent Application SN: not yet assigned.
(CDC Ref. #: I-020-99/0)

Method and Apparatus for Safety Testing Optical Systems for 
Hazardous Locations

    Method of determining the ignition characteristics of an optical 
source emitting optical power into a hazardous environment. The 
invention will allow testing laboratories to efficiently and accurately 
vary the irradiance of optical sources for certifying the safety of 
optical systems in hazardous locations. This new method will improve 
the accuracy of tests, simplifies test setup, reduces setup time, and 
reduces component inventory. The use of fiber tapers, rather than 
external components, reduces the risk of human exposure to potentially 
dangerous optical beams.

Inventors: Thomas Dubaniewicz et al.
U.S. Patent Application SN: not yet received.
(CDC Ref. #: I-015-97/0)

Methods and Compositions for Opsonophagocytic Assays

    This invention describes the use of immunoassays for the detection 
of functional antibodies and the analysis of vaccine efficacy, 
particularly relating to Streptococcus pneumoniae. This method of 
pneumococcal vaccine measurement using ``functional'' opsonophagocytic 
assays is compliant with the new FDA requirements and is a significant 
improvement over existing assays. The invention measures vaccine 
efficacy and allows simultaneous detection of functional antibodies 
generated by multiple serotypes of a pathogen. Antibody response is 
easier and faster to measure and output is significantly increased.

Inventors: Joseph E. Martinez t al.
U.S. Patent Application SN: not yet received.
(CDC Ref. #: I-006-99/0)

    Dated: July 26, 1999.
Joseph R. Carter,
Acting Associate Director for Management and Operations, Centers for 
Disease Control and Prevention (CDC).
[FR Doc. 99-19499 Filed 7-29-99; 8:45 am]
BILLING CODE 4163-18-P