[Federal Register Volume 64, Number 98 (Friday, May 21, 1999)]
[Notices]
[Pages 27785-27786]
From the Federal Register Online via the Government Publishing Office [www.gpo.gov]
[FR Doc No: 99-13017]


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ENVIRONMENTAL PROTECTION AGENCY

[FRL-6348-7]


Draft Toxicological Review of Vinyl Chloride and IRIS Summary for 
Vinyl Chloride

AGENCY: Environmental Protection Agency.

ACTION: Notice of peer-review panel workshop and public comment period.

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SUMMARY: The U.S. Environmental Protection Agency (EPA) is announcing 
an external peer-review workshop to review the external review draft 
document titled, Toxicological Review of Vinyl Chloride (NCEA-S-0619) 
and the companion draft IRIS [Integrated Risk Information System] 
Summary for Vinyl Chloride. The EPA is also announcing a 30-day public 
comment period for the draft Toxicological Review. The peer-review 
workshop will be organized, convened, and conducted by the Syracuse 
Research Corporation, an EPA contractor for this external scientific 
peer review. The documents were prepared by the EPA's National Center 
for Environmental Assessment-Washington Office (NCEA-W) within the 
Office of Research and Development. NCEA will consider the peer-review 
advice and public comment submissions in revising the Toxicological 
Review. While EPA is not soliciting public comments on the draft IRIS 
Summary, any comments on the draft Toxicological Review received prior 
to the end of the public comment period also will be considered in 
revising the IRIS Summary.

DATES: The peer-review panel workshop will begin on Wednesday, June 2, 
1999, at 9:00 a.m. and end at 5:30 p.m. Members of the public may 
attend as observers, and there will be a limited time for comments from 
the public in the afternoon. The 30-day public comment period begins 
May 21, 1999, and ends June 21, 1999.

ADDRESSES: The external peer-review panel workshop will be held at the 
Sheraton Crystal City Hotel, 1800 Jefferson Davis Highway, Arlington, 
Virginia. The Syracuse Research Corporation, an EPA contractor, is 
organizing, convening, and conducting the peer-review workshop. To 
attend the workshop, register by May 27, 1999, by calling Tara Childs, 
Syracuse Research Corporation, 1215 Jefferson Davis Highway, Arlington 
VA 22202 at 703-413-9364, or send a facsimile to 703-418-1044. Space is 
limited, and reservations will be accepted on a first-come, first-
served basis. There will be a limited time for comments from the public 
during the afternoon of the workshop. Please let the Syracuse Research 
Corporation know if you wish to make comments.
    The draft Toxicological Review and the draft IRIS Summary are 
available on the Internet at http://www.epa.gov/ncea under the What's 
New and Publications menus. A limited number of paper copies are 
available from the Technical Information Staff (8623D), NCEA-W; 
telephone: 202-564-3261; facsimile: 202-565-0050. If you are requesting 
a paper copy, please provide your name,

[[Page 27786]]

mailing address, and the document titles, Toxicological Review of Vinyl 
Chloride (NCEA-S-0619) and IRIS Summary for Vinyl Chloride. Copies are 
not available from the Syracuse Research Corporation.
    Comments may be mailed to the Technical Information Staff (8623D), 
NCEA-W, U.S. Environmental Protection Agency, 401 M Street, S.W., 
Washington, DC 20460, or delivered to the Technical Information Staff 
at 808 17th Street, N.W., 5th Floor, Washington, DC 20074; telephone: 
202-564-3261; facsimile: 202-565-0050. Comments should be in writing 
and must be postmarked by June 21, 1999. Please submit one unbound 
original with pages numbered consecutively, and three copies of the 
comments. For attachments, provide an index, number pages consecutively 
with the comments, and submit an unbound original and three copies. 
Electronic comments may be emailed to: [email protected].
    Please note that all technical comments received in response to 
this notice will be placed in a public record. For that reason, 
commentors should not submit personal information (such as medical data 
or home address), Confidential Business Information, or information 
protected by copyright. Due to limited resources, acknowledgments will 
not be sent.

FOR FURTHER INFORMATION CONTACT: For workshop information, 
registration, and logistics, contact Tara Childs, Syracuse Research 
Corporation, 1215 Jefferson Davis Highway, Arlington, Virginia 22202; 
telephone: 703-413-9364; facsimile: 703-418-1044.
    For information on the public comment period, contact William 
Pepelko, NCEA-W, telephone: 202-564-3309; facsimile: 202-565-0078; or 
email: [email protected].

SUPPLEMENTARY INFORMATION: The Toxicological Review of Vinyl Chloride 
will provide the scientific basis for classifying the weight-of-
evidence for the carcinogenicity of vinyl chloride, deriving cancer 
potency estimates for both the inhalation and oral route and deriving 
an oral reference dose (RfD) and inhalation reference concentration 
(RfC) for the noncancer health risk from exposure to vinyl chloride.
    An earlier draft of the Toxicological Review was peer-reviewed at a 
workshop in June 1997 and has been revised based on comments received. 
This is the second peer-review workshop and the first public comment 
period for this document.
    The IRIS Summary for Vinyl Chloride is formulated from the contents 
of the Toxicological Review and is included to provide interested 
parties with the proposed changes to the Agency's Integrated Risk 
Information System (IRIS). While EPA is not soliciting comments on the 
IRIS Summary, any comments on the draft Toxicological Review received 
during the public comment period also will be considered in revising 
IRIS the Summary.

    Dated: May 18, 1999.
William H. Farland,
Director, National Center for Environmental Assessment.
[FR Doc. 99-13017 Filed 5-20-99; 8:45 am]
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