[Federal Register Volume 64, Number 68 (Friday, April 9, 1999)]
[Notices]
[Page 17402]
From the Federal Register Online via the Government Publishing Office [www.gpo.gov]
[FR Doc No: 99-8876]


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DEPARTMENT OF HEALTH AND HUMAN SERVICES

Public Health Service


National Toxicology Program; National Toxicology Program (NTP) 
Board of Scientific Counselors' Meeting; Review of Draft NTP Technical 
Reports.

    Pursuant to Public Law 92-463, notice is hereby given of the next 
meeting of the NTP Board of Scientific Counselors' Technical Reports 
Review Subcommittee on May 21, 1999, in the Rodbell Auditorium, 
Building 101, South Campus, National Institute of Environmental Health 
Sciences (NIEHS), 111 Alexander Drive, Research Triangle Park, North 
Carolina. The meeting will begin at 8:45 a.m. on May 21 and is open to 
the public. The agenda topic is the peer review of draft Technical 
Reports of long-term toxicology and carcinogenesis studies from the 
National Toxicology Program.
    Tentatively scheduled to be peer reviewed on May 21 are draft 
Technical Reports of four two-year studies, listed alphabetically, 
along with supporting information in the attached table. All studies 
were done using Fischer 344 rats and B6C3F1 mice. The order 
of review is given in the far right column of the table. By April 21, 
1999, full copies of these draft reports will be available for free on 
the Internet for public review and comment through the Environmental 
Health Information Service (EHIS) at http://ehis.niehs.nih.gov. Printed 
copies can be obtained, as available, from: Central Data Management, MD 
E1-02, P.O. Box 12233, Research Triangle Park, NC 27709 (919/541-3419), 
FAC (919/541-3687), email: [email protected].
    Public comment on any of the Technical Reports is welcome. Persons 
wanting to make a formal presentation regarding a particular Technical 
Report must notify the Executive Secretary by telephone at 919/541-
3971, by FAX at 919/541-0295, by mail, or by email at 
[email protected], by no later than May 18, 1999, and, if possible, 
provide a written copy in advance of the meeting so copies can be made 
and distributed to all Subcommittee members and staff, and made 
available at the meeting for public.Written statements could supplement 
and may expand on the oral presentation. Oral presentations should be 
limited to no more than five minutes.
    The Program would welcome receiving toxicology and carcinogenesis 
information from completed, ongoing, or planned studies by others as 
well as current production data, human exposure information, and use 
patterns for any of the chemicals listed in this announcement. Please 
contact Central Data Management at the address given above, and they 
will relay the information to the appropriate staff scientist.
    The Executive Secretary, Dr. Larry G. hart, P.O. Box 12233, 
Research Triangle Park, North Carolina 27709, will furnish agenda and a 
roster of Subcommittee members prior to the meeting, Summary minutes 
subsequent to the meeting will be available upon request to Central 
Data Management.

    Dated: April 2, 1999.
Samuel. H. Wilson,
Deputy Director, National Institute of Environmental Health Sciences.

     Summary Data for Technical Reports Tentatively Scheduled for Review at the Meeting of the NTP Board of
                    Scientific Counselor's Technical Reports Review Subcommittee May 21, 1999
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                                     Technical report                                 Route/exposure     Review
         Chemical CAS No.                  No.                 Primary uses               levels          order
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Anthraquinone 84-65-1............  TR-94                Intermediate in the        Feed:..............         3
                                                         manufacture of dyes and   Rats: 0, 469, 938,
                                                         other organics. Organic    1875, or 3750 ppm.
                                                         inhibitor. Catalyst.      Mice: 0, 833, 2500,
                                                         Accelerator in nickel      or 7500 ppm.
                                                         electroplating.
                                                         Improving adhesion and
                                                         heat stability of tire
                                                         cord..
Emodin 518-82-1..................  TR-493               Major component of         Feed:..............         2
                                                         natural laxative drugs    Rats: 0, 280, 830,
                                                         of plant origin.           or 2500 ppm;.
                                                         Medicine, natural plant   Mice: 0, 160, 312,
                                                         dye..                      625, or 1250 pp,
                                                                                    (60/sex/species/
                                                                                    group).
Fumonisin B1 116355-83-0.........  TR-496               Mycotoxin produced by      Feed:..............         4
                                                         certain strains of        Rats & Mice: 0, 15,
                                                         fusarium moniliforme, a    50,100, or 150 ppm.
                                                         commonly occurring fungi
                                                         on U.S. agricultural
                                                         products, especially
                                                         corn. No known uses..
Gallium Arsenide 1303-00-0.......  TR-492               Semiconductors.            Inhalation.........         1
                                                         Magnetoresistance         Rats: 0, 0.01, 0.1,
                                                         devices. Light-emitting    or 1.0 mg/m \3\;.
                                                         diodes. Microwave         Mice: 0, 0.1, 0.5,
                                                         generation..               or 1.0 mg/m \3\,
                                                                                    (50/group).
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[FR Doc. 99-8876 Filed 4-8-99; 8:45 am]
BILLING CODE 4140-01-M