[Federal Register Volume 64, Number 17 (Wednesday, January 27, 1999)]
[Notices]
[Page 4108]
From the Federal Register Online via the Government Publishing Office [www.gpo.gov]
[FR Doc No: 99-1798]


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DEPARTMENT OF HEALTH AND HUMAN SERVICES

Office of the Secretary


Findings of Scientific Misconduct

AGENCY: Office of the Secretary, HHS.

ACTION: Notice.

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SUMMARY: Notice is hereby given that the Office of Research Integrity 
(ORI) has made a final finding of scientific misconduct in the 
following case:
    Samar N. Roy, Ph.D., New York Blood Center: Based on a report 
forwarded to the Office of Research Integrity (ORI) by the New York 
Blood Center (NYBC) on February 26, 1998, and information obtained by 
ORI during its oversight review, ORI found that Dr. Roy, former 
assistant member, Laboratory of Membrane Biochemistry, NYBC, engaged in 
scientific misconduct in biomedical research supported in part by a 
National Heart, Lung, and Blood Institute (NHLBI), National Institutes 
of Health (NIH), grant.
    Specifically, Dr. Roy intentionally falsified the claim reported in 
S.N. Roy, B. Kudryk, and C.M. Redman, J. Biol. Chem. 270:23761-23767 
(1995) (the ``JBC 270 paper'') that he had obtained the expression of 
wild type and mutant fibrinogen in yeast cells. Dr. Roy falsified the 
claim by ``spiking'' various samples with fibrinogen obtained from 
mammalian sources that were submitted to other laboratories for 
analysis. Also, Dr. Roy intentionally falsified the data reported in 
Figure 2A of the JBC 270 paper by using a different exposure of the 
same autoradiogram that he later used in the first six lanes of Figure 
2 reported in S. Roy, A. Sun, and C. Redman, J. Biol. Chem. 271:24544-
24550 (1996) (the ``JBC 271 paper''). The falsified autoradiogram in 
Figure 2A of the JBC 270 paper was described differently, though 
correctly, in Figure 2 of the JBC 271 paper. The JBC 270 paper has been 
retracted.
    Dr. Roy has accepted the ORI finding and has entered into a 
Voluntary Exclusion Agreement with ORI in which he has voluntarily 
agreed, for the three (3) year period beginning January 7, 1999:

(1) To exclude himself from any contracting or subcontracting with any 
agency of the United States Government and from eligibility for, or 
involvement in nonprocurement transactions (e.g., grants and 
cooperative agreements) of the United States Government as defined in 
45 CFR Part 76 (Debarment Regulations); and
(2) To exclude himself from serving in any advisory capacity to the 
Public Health Service (PHS), including but not limited to service on 
any PHS advisory committee, board, and/or peer review committee, or as 
a consultant.

FOR FURTHER INFORMATION CONTACT: Acting Director, Division of Research 
Investigations, Office of Research Integrity, 5515 Security Lane, Suite 
700, Rockville, MD 20852 (301) 443-5330
Chris B. Pascal,
Acting Director, Office of Research Integrity.
[FR Doc. 99-1798 Filed 1-26-99; 8:45 am]
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