[Federal Register Volume 63, Number 161 (Thursday, August 20, 1998)]
[Rules and Regulations]
[Pages 44562-44583]
From the Federal Register Online via the Government Publishing Office [www.gpo.gov]
[FR Doc No: 98-22441]


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ENVIRONMENTAL PROTECTION AGENCY

40 CFR Part 721

[OPPTS-50632; FRL-5788-7]
RIN 2070-AB27


Significant New Uses of Certain Chemical Substances

AGENCY: Environmental Protection Agency (EPA).

ACTION: Final rule.

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SUMMARY: EPA is promulgating significant new use rules (SNURs) under 
section 5(a)(2) of the Toxic Substances Control Act (TSCA) for 73 
chemical substances which were the subject of premanufacture notices 
(PMNs) and subject to TSCA section 5(e) consent orders issued by EPA. 
Today's action requires persons who intend to manufacture, import, or 
process these substances for a significant new use to notify EPA at 
least 90 days before commencing the manufacturing or processing of the 
substance for a use designated by this SNUR as a significant new use. 
The required notice will provide EPA with the opportunity to evaluate 
the intended use, and if necessary, to prohibit or limit that activity 
before it occurs. EPA is promulgating this SNUR using direct final 
procedures.

DATES: The effective date of this rule is October 19, 1998. This rule 
shall be promulgated for purposes of judicial review at 1 p.m. (e.s.t.) 
on September 3, 1998.
    If EPA receives notice before October 19, 1998 that someone wishes 
to submit adverse or critical comments on EPA's action in establishing 
a SNUR for one or more of the chemical substances subject to this rule, 
EPA will withdraw the SNUR for the substance for which the notice of 
intent to comment is received and will issue a proposed SNUR providing 
a 30-day period for public comment.

ADDRESSES: Each comment or notice of intent to submit adverse or 
critical comment must bear the docket control number OPPTS-50632 and 
the name(s) of the chemical substance(s) subject to the comment. All 
comments should be sent in triplicate to: OPPT Document Control Officer 
(7407), Office of Pollution Prevention and Toxics, Environmental 
Protection Agency, 401 M St., SW., Rm. G-099, East Tower, Washington, 
DC 20460.
    Comments and data may also be submitted electronically to: 
[email protected]. Follow the instructions under Unit X. of this 
document. No Confidential Business Information (CBI) should be 
submitted through e-mail.
    All comments which contain information claimed as CBI must be 
clearly marked as such. Three sanitized copies of any comments 
containing information claimed as CBI must also be submitted and will 
be placed in the public record for this rulemaking. Persons submitting 
information on any portion of which they believe is entitled to 
treatment as CBI by EPA must assert a business confidentiality claim in 
accordance with 40 CFR 2.203(b) for each portion. This claim must be 
made at the time that the information is submitted to EPA . If a 
submitter does not assert a confidentiality claim at the time of 
submission, EPA will consider this as a waiver of any confidentiality 
claim and the information may be made available to the public by EPA 
without further notice to the submitter.

FOR FURTHER INFORMATION CONTACT: Susan B. Hazen, Director, 
Environmental Assistance Division (7408), Office of Pollution 
Prevention and Toxics, Environmental Protection Agency, Rm. E-531, 401 
M St., SW., Washington, DC 20460, telephone: (202) 554-1404, TDD: (202) 
554-0551; e-mail: TSCA-H[email protected].

SUPPLEMENTARY INFORMATION:
    Electronic Availability: Electronic copies of this document are 
available from the EPA Home Page at the Federal Register-Environmental 
Documents entry for this document under ``Laws and Regulations'' 
(http://www.epa.gov/fedrgstr/).
    This SNUR will require persons to notify EPA at least 90 days 
before commencing manufacturing or processing a substance for any 
activity designated by this SNUR as a significant new use. The 
supporting rationale and background to this rule are more fully set out 
in the preamble to EPA's first direct final SNURs published in the 
Federal Register of April 24, 1990 (55 FR 17376). Consult that preamble 
for further information on the objectives, rationale, and procedures 
for the rules and on the basis for significant new use designations 
including provisions for developing test data.

I. Authority

    Section 5(a)(2) of TSCA (15 U.S.C. 2604(a)(2)) authorizes EPA to 
determine that a use of a chemical substance is a ``significant new 
use.'' EPA must make this determination by rule after considering all 
relevant factors, including those listed in section 5(a)(2) of TSCA. 
Once EPA determines that a use of a chemical substance is a

[[Page 44563]]

significant new use, section 5(a)(1)(B) of TSCA requires persons to 
submit a notice to EPA at least 90 days before they manufacture, 
import, or process the substance for that use. The mechanism for 
reporting under this requirement is established under 40 CFR 721.10.

II. Applicability of General Provisions

    General provisions for SNURs appear under subpart A of 40 CFR part 
721. These provisions describe persons subject to the rule, 
recordkeeping requirements, exemptions to reporting requirements, and 
applicability of the rule to uses occurring before the effective date 
of the final rule. Provisions relating to user fees appear at 40 CFR 
part 700. Persons subject to this SNUR must comply with the same notice 
requirements and EPA regulatory procedures as submitters of PMNs under 
section 5(a)(1)(A) of TSCA. In particular, these requirements include 
the information submission requirements of TSCA section 5(b) and 
5(d)(1), the exemptions authorized by TSCA section 5 (h)(1), (2), (3), 
and (5), and the regulations at 40 CFR part 720. Once EPA receives a 
SNUR notice, EPA may take regulatory action under TSCA section 5 (e), 
5(f), 6, or 7 to control the activities on which it has received the 
SNUR notice. If EPA does not take action, EPA is required under TSCA 
section 5(g) to explain in the Federal Register its reasons for not 
taking action.
    Persons who intend to export a substance identified in a proposed 
or final SNUR are subject to the export notification provisions of TSCA 
section 12(b). The regulations that interpret TSCA section 12(b) appear 
at 40 CFR part 707. Persons who intend to import a chemical substance 
identified in a final SNUR are subject to the TSCA section 13 import 
certification requirements, which are codified at 19 CFR 12.118 through 
12.127 and 127.28. Such persons must certify that they are in 
compliance with SNUR requirements. The EPA policy in support of the 
import certification appears at 40 CFR part 707.

III. Substances Subject to This Rule

    EPA is establishing significant new use and recordkeeping 
requirements for the following chemical substances under 40 CFR part 
721, subpart E. In this unit, EPA provides a brief description for each 
substance, including its PMN Number, chemical name (generic name if the 
specific name is claimed as CBI), CAS number (if assigned for non-
confidential chemical identities), basis for the action taken by EPA in 
the TSCA section 5(e) consent order or as a non-section 5(e) SNUR for 
the substance (including the statutory citation and specific finding), 
toxicity concern, and the CFR citation assigned in the regulatory text 
section of this rule. The specific uses which are designated as 
significant new uses are cited in the regulatory text section of this 
document by reference to 40 CFR part 721, subpart E where the 
significant new uses are described in detail. Certain new uses, 
including production limits and other uses designated in the rule are 
claimed as CBI. The procedure for obtaining confidential information is 
set out in Unit VII. of this preamble.
    Where the underlying TSCA section 5(e) consent order prohibits the 
PMN submitter from exceeding a specified production limit without 
performing specific tests to determine the health or environmental 
effects of a substance, the tests are described in this unit. As 
explained further in Unit VI. of this preamble, the SNUR for such 
substances contains the same production limit, and exceeding the 
production limit is defined as a significant new use. Persons who 
intend to exceed the production limit must notify the Agency by 
submitting a significant new use notice (SNUN) at least 90 days in 
advance. In addition, this unit describes tests that are recommended by 
EPA to provide sufficient information to evaluate the substance, but 
for which no production limit has been established in the TSCA section 
5(e) consent order. Descriptions of recommended tests are provided for 
informational purposes.
    Data on potential exposures or releases of the substances, testing 
other than that specified in the TSCA section 5(e) consent order for 
the substances, or studies on analogous substances, which may 
demonstrate that the significant new uses being reported do not present 
an unreasonable risk, may be included with significant new use 
notification. Persons submitting a SNUN must comply with the same 
notice requirements and EPA regulatory procedures as submitters of 
PMNs, as stated in 40 CFR 721.1(c), including submission of test data 
on health and environmental effects as described in 40 CFR 720.50.
    EPA is not publishing SNURs for PMNs P-95-2040, P-97-77, P-97-118, 
P-97-214, P-98-5/6/7/8/9/10 which are subject to a final TSCA section 
5(e) consent order. The TSCA section 5(e) consent orders for these 
substances are derived from an exposure finding based solely on 
substantial production volume and significant or substantial human 
exposure and/or release to the environment of substantial quantities. 
For these cases there were limited or no toxicity data available for 
the PMN substances. In such cases, EPA regulates the new chemical 
substances under TSCA section 5(e) by requiring certain toxicity tests. 
For instance, chemical substances with potentially substantial releases 
to surface waters would be subject to toxicity testing of aquatic 
organisms and chemicals with potentially substantial human exposures 
would be subject to health effects testing for mutagenicity, acute 
effects, and subchronic effects. However, for these substances, the 
short-term toxicity testing required by the TSCA section 5(e) consent 
order is usually completed within 1 to 2 years of notice of 
commencement. EPA's experience with exposure-based SNURs requiring 
short-term testing is that the SNUR is often revoked within 1 to 2 
years when the test results are received. Rather than issue and revoke 
SNURs in such a short span of time, EPA will defer publication of 
exposure-based SNURs until either a notice of commencement (NOC) or 
data demonstrating risk are received unless the toxicity testing 
required is long-term. EPA is issuing this explanation and notification 
as required in 40 CFR 721.160(a)(2) as it has determined that SNURs are 
not needed at this time for these substances which are subject to a 
final section 5(e) consent order under TSCA.

PMN Numbers P-93-880/881

Chemical names: Amines, N-cocoalkyltrimethylenedi-, citrates (P-93-
880); Amines, N-tallowalkyltripropylenetetra-, citrates (P-93-881).
CAS number: 189120-63-6 (P-93-880); 189120-62-5 (P-93-881).
Effective date of section 5(e) consent order: September 4, 1997.
Basis for section 5(e) consent order: The order was issued under 
section 5(e)(1)(A)(i), (e)(1)(A)(ii)(I), and (e)(1)(A)(II) of TSCA 
based on a finding that these substances may present an unreasonable 
risk of injury to the environment, that the PMN substances will be 
produced in substantial quantities, and there may be significant or 
substantial environmental exposure to the substances.
Toxicity concern: Based on test data for the substances and test data 
on structurally similar aliphatic amines, there is concern for toxicity 
to aquatic organisms at concentrations as low as 2 parts per billion 
(ppb) in surface waters.
Recommended testing: EPA has determined that a fish acute toxicity 
study (40 CFR 797.1400 or OPPTS 850.1075 test guideline (public draft; 
61 FR 16486, April 15, 1996) (FRL-5363-1)), a fish acute toxicity 
mitigated by dissolved organic carbon (humic acid

[[Page 44564]]

test) (OPPTS 850.1085 test guideline (public draft; 61 FR 16486, April 
15, 1996) (FRL-5363-1)), a daphnid acute toxicity study (40 CFR 
797.1300 or OPPTS 850.1010 test guideline (public draft; 61 FR 16486, 
April 15, 1996) (FRL-5363-1)), and an algal acute toxicity study (40 
CFR 797.1050 or OPPTS 850.5400 test guideline (public draft; 61 FR 
16486, April 15, 1996) (FRL-5363-1)) would help characterize the 
environmental effects of the PMN substance.
CFR citations: 40 CFR 721.7285 (P-93-880); 40 CFR 721.7286 (P-93-881).

PMN Number P-95-1098

Chemical name: (generic) Tris carbamoyl triazine.
CAS number: Not available.
Effective date of section 5(e) consent order: April 25, 1997.
Basis for section 5(e) consent order: The order was issued under 
section 5(e)(1)(A)(i), (e)(1)(A)(ii)(I), and (e)(1)(A)(ii)(II) of TSCA 
based on a finding that this substance may present an unreasonable risk 
of injury to the environment, that the PMN substance will be produced 
in substantial quantities, and there may be significant or substantial 
human exposure to the substance.
Toxicity concern: Based on test data for the substance, there is 
concern for toxicity to aquatic organisms at concentrations as low as 
40 ppb in surface waters. The health testing required in the order is 
based on the exposure based finding pursuant to section 
5(e)(1)(A)(ii)(II) of TSCA.
Recommended testing: EPA has determined that a chronic 60-day fish 
early life stage toxicity test in rainbow trout (40 CFR 797.1600 or 
OPPTS 850.1400 test guideline (public draft; 61 FR 16486, April 15, 
1996) (FRL-5363-1)) and a 21-day daphnid chronic toxicity test (40 CFR 
797.1330 or OPPTS 850.1300 test guideline (public draft; 61 FR 16486, 
April 15, 1996)) (FRL-5363-1)) would help characterize the 
environmental effects of the PMN substance. The PMN submitter has 
agreed to conduct a prenatal developmental toxicity study by the oral 
route in one-species (40 CFR 799.9370) (62 FR 43832, August 15, 1997) 
(FRL-5719-5) before exceeding the production volume limit.
CFR citation: 40 CFR 721.9719.

PMN Numbers P-96-756/757/758

Chemical names: (generic) 1-Piperidinecarboxylic acid, 2-[(dichloro-
hydroxy-carbomonocycle)hydrazono]-, methyl ester (P-96-756); (generic) 
Dichloro, hydroxy, hydrazino-carbomonocycle (P-96-757); (generic) 
Dichloro, hydroxy, hydrazino-carbomonocycle-monohydrochloride (P-96-
758).
CAS number: Not available.
Effective date of section 5(e) consent order: August 29, 1997.
Basis for section 5(e) consent order: The order was issued under 
section 5(e)(1)(A)(i), (e)(1)(A)(ii)(I), and (e)(1)(A)(II) of TSCA 
based on a finding that the substances may present an unreasonable risk 
of injury to health, that the substances are expected to be produced in 
substantial quantities, and there may be significant or substantial 
human exposure to the substances.
Toxicity concern: Structurallyt similar chemicals have been shown to 
cause effects to internal organs and cancer in test animals.
Recommended testing: A 90-day oral subchronic toxicity in rats (40 CFR 
798.2650 or OPPTS 870.3100 test guideline (63 FR 41845, August 5, 1998) 
(FRL-5740-1)) and a two-species carcinogenicity study (40 CFR 799.9420) 
(62 FR 43838, August 15, 1997) (FRL-5719-5) are recommended to help 
characterize health effects. The PMN submitter has agreed not to exceed 
the production volume limit without performing the 90-day oral 
subchronic toxicity test for P-96-756.
CFR citations: 40 CFR 721.2078 (P-96-756); 40 CFR 721.2079 (P-96-757); 
40 CFR 721.2081 (P-96-758).

PMN Number P-96-1006

Chemical name: 1,3-Dioxolane, 2-ethenyl-.
CAS number: 3984-22-3.
Effective date of section 5(e) consent order: May 1, 1997.
Basis for section 5(e) consent order: The order was issued under 
section 5(e)(1)(A)(i) and (e)(1)(A)(ii)(I) of TSCA based on a finding 
that this substance may present an unreasonable risk of injury to human 
health.
Toxicity concern: Based on submitted acute toxicity testing by the 
dermal (LD50 = 25.1 milligram/kilogram (mg/kg)) and oral 
(LD50 = 84.7 mg/kg) routes, exposure to the substance may 
result in fatality, central nervous system effects, liver toxicity, and 
irritation to the skin and eyes.
Recommended testing: EPA has determined that a 90-day subchronic 
inhalation study (40 CFR 799.9346) (62 FR 43828, August 15, 1997) (FRL-
5719-5) and a 90-day subchronic dermal study (40 CFR 798.2250 or OPPTS 
870.3250 test guideline (63 FR 41845, August 5, 1998) (FRL-5740-1)) 
would help characterize the health effects of the PMN substance.
CFR citation: 40 CFR 721.2485.

PMN Number P-96-1320

Chemical name: (generic) Isoalkyldimethylamine.
CAS number: Not available.
Basis for action: The PMN substance will be used as an intermediate. 
Based on structure activity analogy to aliphatic amines, EPA is 
concerned that toxicity to aquatic organisms may occur at a 
concentration as low as 3 ppb of the PMN substance in surface waters. 
EPA determined that use of the substance as described in the PMN did 
not present an unreasonable risk because the substance would not be 
released to surface waters in significant quantities. EPA has 
determined that other uses of the substance may result in releases to 
surface waters which exceed the concern concentration. Based on this 
information the PMN substance meets the concern criteria at 
Sec. 721.170(b)(4)(ii).
Recommended testing: EPA has determined that a fish acute toxicity 
study (40 CFR 797.1400 or OPPTS 850.1075 test guideline (public draft; 
61 FR 16486, April 15, 1996) (FRL-5363-1)), a daphnid acute toxicity 
study (40 CFR 797.1300 or OPPTS 850.1010 test guideline (public draft; 
61 FR 16486, April 15, 1996) (FRL-5363-1)), and an algal acute toxicity 
study (40 CFR 797.1050 or OPPTS 850.5400 test guideline (public draft; 
61 FR 16486, April 15, 1996) (FRL-5363-1)) would help characterize the 
environmental effects of the PMN substance.
CFR citation: 40 CFR 721.2480.

PMN Numbers P-96-1425/1426

Chemical names: (generic) Salt of a modified tallow alkylenediamine (P-
96-1425); salt of a fatty alkylamine derivative (P-96-1426).
CAS number: Not available.
Basis for action: The PMN substances will be used as processing aids. 
Based on structure activity analogy to aliphatic amines, EPA is 
concerned that toxicity to aquatic organisms may occur at a 
concentration as low as 1 ppb of the PMN substances in surface waters. 
EPA determined that use of the substances as described in the PMNs did 
not present an unreasonable risk because the substances would not be 
released to surface waters. EPA has determined that other uses of the 
substances may result in releases to surface waters which exceed the 
concern concentration. Based on this information the PMN substances 
meets the concern criteria at Sec. 721.170(b)(4)(ii).
Recommended testing: EPA has determined that a fish acute toxicity 
study (40 CFR 797.1400 or OPPTS 850.1075 test guideline public draft; 
61

[[Page 44565]]

FR 16486, April 15, 1996) (FRL-5363-1)), a daphnid acute toxicity study 
(40 CFR 797.1300 or OPPTS 850.1010 test guideline (public draft; 61 FR 
16486, April 15, 1996) (FRL-5363-1)), and an algal acute toxicity study 
(40 CFR 797.1050 or OPPTS 850.5400 test guideline (public draft; 61 FR 
16486, April 15, 1996) (FRL-5363-1)) would help characterize the 
environmental effects of the PMN substances.
CFR citations: 40 CFR 721.630 (P-96-1425); 40 CFR 721.558 (P-96-1426).

PMN Number P-96-1428

Chemical name: (generic) Modified polyisocyanates.
CAS number: Not available.
Effective date of section 5(e) consent order: July 7, 1997.
Basis for section 5(e) consent order: The order was issued under 
section 5(e)(1)(A)(i) and 5(e)(1)(A)(ii)(I) of TSCA based on a finding 
that this substance may present an unreasonable risk of injury to 
health.
Toxicity concern: Structurally similar chemicals have been shown to 
cause skin irritation and allergic reactions, respiratory irritation 
and sensitization, and lung toxicity in test animals.
Recommended testing: A 90-day subchronic inhalation toxicity study in 
rats (40 CFR 799.9346) (62 FR 43828, August 15, 1997) (FRL-5719-5) will 
help the Agency to characterize the human health effects of the PMN 
substance. The PMN submitter has agreed not to exceed the production 
volume limit without performing the 90-day study.
CFR citation: 40 CFR 721.6498.

PMN Number P-96-1520

Chemical name: Octadecanoic acid, ester with 1,2-propanediol, 
phosphate, anhydride with silicic acid (H4SiO4).
CAS number: 177771-31-2.
Effective date of section 5(e) consent order: July 8, 1997.
Basis for section 5(e) consent order: The order was issued under 
section 5 (e)(1)(A)(i), (e)(1)(A)(ii)(I), and (e)(1)(A)(ii)(II) of TSCA 
based on a finding that this substance may present an unreasonable risk 
of injury to the environment, that this substance is expected to be 
produced in substantial quantities, and there may be significant or 
substantial environmental exposure to the substance.
Toxicity concern: Structurally similar chemicals have been shown to 
cause toxicity in aquatic organisms.
Recommended testing: EPA has determined that a fish acute toxicity 
study (40 CFR 797.1400 or OPPTS 850.1075 test guideline public draft; 
61 FR 16486, April 15, 1996) (FRL-5363-1)), a daphnid acute toxicity 
study (40 CFR 797.1300 or OPPTS 850.1010 test guideline (public draft; 
61 FR 16486, April 15, 1996) (FRL-5363-1)), and an algal acute toxicity 
study (40 CFR 797.1050 or OPPTS 850.5400 test guideline (public draft; 
61 FR 16486, April 15, 1996) (FRL-5363-1)) would help characterize the 
environmental effects of the PMN substance. The PMN submitter has 
agreed not to exceed the production volume limit without performing 
these tests.
CFR citation: 40 CFR 721.3635.

PMN Number P-97-4

Chemical name: (generic) Substituted diphenylmethane.
CAS number: Not available.
Basis for action: The PMN substance will be used as a raw material for 
manufacture of light stabilizers. Based on submitted test data, EPA is 
concerned that toxicity to aquatic organisms may occur at a 
concentration as low as 10 ppb of the PMN substance in surface waters. 
EPA determined that use of the substance as described in the PMN did 
not present an unreasonable risk because the substance would not be 
released to surface waters. EPA has determined that other uses of the 
substance may result in releases to surface waters which exceed the 
concern concentration. Based on this information the PMN substances 
meets the concern criteria at Sec. 721.170(b)(4)(i).
Recommended testing: EPA has determined that a chronic 60-day fish 
early life stage toxicity test in rainbow trout (40 CFR 797.1600 or 
OPPTS 850.1400 test guideline (public draft; 61 FR 16486, April 15, 
1996) (FRL-5363-1)), a 21-day daphnid chronic toxicity test (40 CFR 
797.1330 or OPPTS 850.1300 test guideline (public draft; 61 FR 16486, 
April 15, 1996) (FRL-5363-1)), and an algal acute toxicity study (40 
CFR 797.1050 or OPPTS 850.5400 test guideline (public draft; 61 FR 
16486, April 15, 1996) (FRL-5363-1)) would help characterize the 
environmental effects of the PMN substance.
CFR citation: 40 CFR 721.2532.

PMN Numbers P-97-42/43

Chemical name: (generic) Phenylazoalkoxy naphthylamines.
CAS number: Not available.
Basis for action: The PMN substances will be used as petroleum 
additives. Based on structual activity analogy to neutral organics, EPA 
is concerned that toxicity to aquatic organisms may occur at a 
concentration as low as 50 ppb for P-97-42 and 40 ppb for P-97-43 in 
surface waters. EPA determined that use of the substances as described 
in the PMNs did not present an unreasonable risk because the substances 
would not be released to surface waters in significant quantities. EPA 
has determined that other uses of the substances may result in releases 
to surface waters which exceed the concern concentration. Based on this 
information the PMN substances meet the concern criteria at 
Sec. 721.170(b)(4)(ii).
Recommended testing: EPA has determined that a chronic 60-day fish 
early life stage toxicity test in rainbow trout (40 CFR 797.1600 or 
OPPTS 850.1400 test guideline (public draft; 61 FR 16486, April 15, 
1996) (FRL-5363-1)) and a 21-day daphnid chronic toxicity test (40 CFR 
797.1330 or OPPTS 850.1300 test guideline (public draft; 61 FR 16486, 
April 15, 1996) (FRL-5363-1)) would help characterize the environmental 
effects of the PMN substances.
CFR citation: 40 CFR 721.5290.

PMN Numbers P-97-93/94

Chemical names: (generic) Di-substituted acetophenone (P-97-93); 
(generic) Di-substituted propanedione (P-97-94).
CAS number: Not available.
Effective date of section 5(e) consent order: June 9, 1997.
Basis for section 5(e) consent order: The order was issued under 
section 5(e)(1)(A)(i) and 5(e)(1)(A)(ii)(I) of TSCA based on a finding 
that these substances may present an unreasonable risk of injury to 
health.
Toxicity concern: Based on submitted test data for P-97-94 the 
substances may cause liver, kidney, adrenal gland, and heart toxicity 
in test animals.
Recommended testing: EPA has determined that a glove permeation study 
according to American Society for Testing and Materials (ASTM) F739, an 
in vitro dermal absorption study published in the Federal Register on 
April 3, 1996 (61 FR 14773) (FRL-5359-3) and a 90-day gavage study in 
rats (40 CFR 798.2650 or OPPTS 870.3100 test guideline (63 FR 41845, 
August 5, 1998) (FRL-5740-1)) would help characterize the health 
effects of the PMN substance. The PMN submitter has agreed not to 
exceed the production volume limit without performing these tests.
CFR citations: 40 CFR 721.305 (P-97-93); 40 CFR 721.8153 (P-97-94).

PMN Numbers P-97-179/783, P-97-181/781, P-97-189/769, and P-97-775/782

Chemical name: (generic) Zirconium dichlorides.
CAS number: Not available.
Basis for action: The PMN substances will be used as polymerization 
catalysts.

[[Page 44566]]

Based on structural activity analogy to organo zirconium compounds, EPA 
is concerned that toxicity to aquatic organisms may occur at a 
concentration as low as 1 ppb of the PMN substances in surface waters. 
EPA determined that use of the substances as described in the PMNs did 
not present an unreasonable risk because the substances would not be 
released to surface waters in significant quantities. EPA has 
determined that other uses of the substances may result in releases to 
surface waters which exceed the concern concentration. Based on this 
information the PMN substances meets the concern criteria at 
Sec. 721.170(b)(4)(ii).
Recommended testing: EPA has determined that a fish acute toxicity 
study (40 CFR 797.1400 or OPPTS 850.1075 test guideline (public draft; 
61 FR 16486, April 15, 1996) (FRL-5363-1)), a daphnid acute toxicity 
study (40 CFR 797.1300 or OPPTS 850.1010 test guideline (public draft; 
61 FR 16486, April 15, 1996) (FRL-5363-1)), and an algal acute toxicity 
study (40 CFR 797.1050 or OPPTS 850.5400 test guideline (public draft; 
61 FR 16486, April 15, 1996) (FRL-5363-1)) would help characterize the 
environmental effects of the PMN substances.
CFR citation: 40 CFR 721.9973.

PMN Numbers P-97-296/297/298/299

Chemical name: (generic) Alkyl benzene sulfonic acids and alkyl 
sulfates, amine salts.
CAS number: Not available.
Basis for action: The PMN substances will be used as polymerization 
catalysts. Based on submitted test data and structural activity analogy 
to anionic surfactants, EPA is concerned that toxicity to aquatic 
organisms may occur at a concentration as low as 30 ppb of the PMN 
substances in surface waters. EPA determined that use of the substances 
as described in the PMN did not present an unreasonable risk because 
the substances would not be released to surface waters in significant 
quantities. EPA has determined that other uses of the substances may 
result in releases to surface waters which exceed the concern 
concentration. Based on this information the PMN substances meets the 
concern criteria at Sec. 721.170(b)(4)(i) and (b)(4)(ii).
Recommended testing: EPA has determined that a fish acute toxicity 
study (40 CFR 797.1400 or OPPTS 850.1075 test guideline (public draft; 
61 FR 16486, April 15, 1996) (FRL-5363-1)), a daphnid acute toxicity 
study (40 CFR 797.1300 or OPPTS 850.1010 test guideline (public draft; 
61 FR 16486, April 15, 1996) (FRL-5363-1)), and an algal acute toxicity 
study (40 CFR 797.1050 or OPPTS 850.5400 test guideline (public draft; 
61 FR 16486, April 15, 1996)(FRL-5363-1)) would help characterize the 
environmental effects of the PMN substances.
CFR citation: 40 CFR 721.9595.

PMN Number P-97-332

Chemical name: Siloxanes and silicones, de-Me, 3-[4-[[[3(dimethylamino) 
propyl]amino] carbonyl]-2-oxo-1-pyrrolidinyl] propyl Me.
CAS number: 179005-02-8.
Basis for action: The PMN substance will be used as an intermediate in 
a multiple step synthesis. Test data on structurally similar chemical 
substances which the Agency has received under section 8(e) of TSCA 
raised concerns for lung toxicity. EPA determined that use of the PMN 
substance as an intermediate as described in the PMN did not present an 
unreasonable risk because workers would not be subject to significant 
inhalation exposures. However, EPA has identified other potential uses 
which may result in significant inhalation exposures to workers. Based 
on this information the PMN substance meets the concern criteria at 
721.170(b)(3)(ii).
Recommended testing: EPA has determined that the results of an acute 
inhalation toxicity test in rats (OPPTS 870.1300 test guideline (63 FR 
41845, August 5, 1998) (FRL-5740-1)) and a 90-day subchronic inhalation 
study (40 CFR 799.9346) (62 FR 43828, August 15, 1997) (FRL-5719-5) 
would help characterize the health effects of the PMN substance.
CFR citation: 40 CFR 721.9517.

PMN Number P-97-370

Chemical name: (generic) Propionic acid methyl ester.
CAS number: Not available.
Basis for action: The PMN substance will be used as a solvent. Based on 
submitted test data, there is concern for developmental toxicity. EPA 
determined that use of the substance as described in the PMN did not 
present an unreasonable risk because significant worker exposure would 
not result if dermal protection were used by workers and only if the 
specific uses stated in the PMN apply. EPA has determined that 
manufacture, processing, or use of the substance without dermal 
protection, for uses other than stated in the PMN, and domestic 
manufacture may result in significant exposure to workers. Based on 
this information the PMN substance meets the concern criteria at 
Sec. 721.170(b)(3)(i).
Recommended testing: None.
CFR citation: 40 CFR 721.8660.

PMN Number P-97-497

Chemical name: Poly(oxy-1,2-ethanediyl), alpha, alpha'- [thiobis(1-oxo-
3,1-propanediyl)] bis[omega-hydroxy-,bis (C11-15 and 
C11-15-isoalkyl) ethers.
CAS number: 174254-18-3.
Basis for action: The PMN substance will be used as a spin finish for 
industrial polyamide fibers. Based on analogy to nonionic surfactants, 
EPA is concerned that toxicity to aquatic organisms may occur at a 
concentration as low as 2 ppb of the PMN substance in surface waters. 
EPA determined that use of the substance did not present an 
unreasonable risk because significant releases would not occur. EPA has 
determined that uses other than those specified in the PMN may result 
in significant environmental exposure. Based on this information the 
PMN substance meets the concern criteria at Sec. 721.170(b)(4)(ii).
Recommended testing: EPA has determined that a fish acute toxicity 
study (40 CFR 797.1400 or OPPTS 850.1075 test guideline (public draft; 
61 FR 16486, April 15, 1996) (FRL-5363-1)) and an algal acute toxicity 
study (40 CFR 797.1050 or OPPTS 850.5400 test guideline (public draft; 
61 FR 16486, April 15, 1996) (FRL-5363-1)) would help characterize the 
environmental effects of the PMN substance.
CFR citation: 40 CFR 721.9663.

PMN Numbers P-97-520/521

Chemical names: 2-Piperdinone, 1,3-dimethyl- (P-97-520); 2-piperdinone, 
1,5-dimethyl- (P-97-521).
CAS number: 1690-76-2 (P-97-520); 86917-58-0 (P-97-521).
Basis for action: The PMN substances will be used as semiconductor 
cleaning solvents. Based on structrual activity analogy to 2-
piperdinone, N-methylpyrrolidone, and other similarly analogous 
substances, there is concern for neurotoxicity, developmental toxicity, 
and reproductive toxicity. EPA determined that the stated use of the 
substances as described in the PMN did not present an unreasonable risk 
because significant worker or general population exposure would not 
result. EPA has determined that manufacture, processing, or use of the 
substances other than for the use stated in the PMN may result in 
significant exposure to workers or the general population. Based on 
this information the PMN substances meet the concern criteria at 
Sec. 721.170 (b)(3)(ii).
Recommended testing: EPA has determined that a 90-day oral subchronic 
toxicity study in rats (40

[[Page 44567]]

CFR 798.2650 or OPPTS 870.3100 test guideline (63 FR 41845, August 5, 
1998) (FRL-5740-1)), a reproduction and fertility effects study in rats 
by the oral route (40 CFR 799.9380) (62 FR 43834, August 15, 1997) 
(FRL-5719-5), and a prenatal developmental toxicity study by the oral 
route in two-species (40 CFR 799.9370) (62 FR 43832, August 15, 1997) 
(FRL-5719-5) would help characterize the human health effects of the 
PMN substances.
CFR citations: 40 CFR 721.6175 (P-97-520); 40 CFR 721.6176 (P-97-521).

PMN Numbers P-97-552/553

Chemical names: Boric acid (H3BO3), zinc salt 
(2=3) (P-97-552); Boric acid (H3BO2), zinc salt 
(P-97-553).
CAS number: 10192-46-8 (P-97-552); 14720-55-9 (P-97-553).
Basis for action: The PMN substances will be used as nucleating agents 
for no-stick automotive glass coating. Based on structural activity 
analogy to zinc and boron compounds, EPA is concerned that toxicity to 
aquatic organisms may occur at a concentration as low as 3 ppb of the 
PMN substances in surface waters. EPA determined that use of the 
substances as described in the PMN did not present an unreasonable risk 
because the substances would not be released to surface waters in 
significant quantities. EPA has determined that other uses of the 
substances may result in releases to surface waters which exceed the 
concern concentration. Based on this information the PMN substances 
meet the concern criteria at Sec. 721.170(b)(4)(ii).
Recommended testing: EPA has determined that a fish acute toxicity 
study (40 CFR 797.1400 or OPPTS 850.1075 test guideline (public draft; 
61 FR 16486, April 15, 1996) (FRL-5363-1)), a daphnid acute toxicity 
study (40 CFR 797.1300 or OPPTS 850.1010 test guideline (public draft; 
61 FR 16486, April 15, 1996) (FRL-5363-1)), and an algal acute toxicity 
study (40 CFR 797.1050 or OPPTS 850.5400 test guideline (public draft; 
61 FR 16486, April 15, 1996) (FRL-5363-1)) would help characterize the 
environmental effects of the PMN substances.
CFR citations: 40 CFR 721.3031 (P-97-552); 40 CFR 721.3032 (P-97-553).

PMN Numbers P-97-582 and P-97-583

Chemical name: (generic) Substituted heteroaromatic-2 [[4-
(dimethylamino)phenyl] azo]-3-methyl-, salts.
CAS number: Not available.
Basis for action: The PMN substances will be used as textile dyes. 
Based on the submitted test data, structural activity analogy to a 
similar delocalized cationic dye, the aniline-based azo reduction 
product, analogy to Butter Yellow, and analogy to trichlorozincate, EPA 
is concerned that the PMN substances may cause developmental toxicity, 
carcinogenicity, neurotoxicity, acute and chronic toxicity, severe eye 
irritation and corrosivity, blood toxicity, and mutagenicity. EPA 
determined that use of the substances as described in the PMN did not 
present an unreasonable risk because there were no significant worker 
exposures. EPA has determined that domestic manufacture of the PMN 
substances may result in significant worker exposures. Based on this 
information the PMN substances meet the concern criteria at 
Sec. 721.170 (b)(1)(i)(C), (b)(2), (b)(3)(ii), and (b)(3)(iii).
Recommended testing: EPA has determined that a 90-day oral subchronic 
toxicity study in rats (40 CFR 798.2650 or OPPTS 870.3100 test 
guideline (63 FR 41845, August 5, 1998) (FRL-5740-1)), an oral two-
species carcinogenicity study (40 CFR 799.9420) (62 FR 43838, August 
15, 1997) (FRL-5719-5) and a prenatal developmental toxicity study by 
the oral route in two-species (40 CFR 799.9370) (62 FR 43832, August 
15, 1997) (FRL-5719-5) would help characterize the health effects of 
the PMN substances.
CFR citation: 40 CFR 721.4098.

PMN Number P-97-593

Chemical name: (generic) Hydrofluorochloroalkene.
CAS number: Not available.
Basis for action: The PMN substance will be used as an intermediate. 
Based on structural activity analogy to similar substances and toxicity 
data submitted with the PMN, EPA is concerned that mutagencity, 
neurotoxicity, immunotoxicity, carcinogenicity, liver toxicity, and 
kidney toxicity will occur in exposed workers. EPA determined that use 
of the substance as an intermediate did not present an unreasonable 
risk because it did not result in significant worker exposure. EPA has 
determined that use other than an as intermediate may result in 
significant worker exposure. Based on this information the PMN 
substance meets the concern criteria at Sec. 721.170(b)(1)(i)(B), 
(b)(3)(i), and (b)(3)(ii).
Recommended testing: EPA has determined that a 90-day oral subchronic 
toxicity study in rats (40 CFR 798.2650 or OPPTS 870.3100 test 
guideline (63 FR 41845, August 5, 1998) (FRL-5740-1)) and an oral two-
species carcinogenicity study (40 CFR 799.9420) (62 FR 43838, August 
15, 1997) (FRL-5719-5) would help characterize the health effects of 
the PMN substance.
CFR citation: 40 CFR 721.450.

PMN Number P-97-740

Chemical name: Siloxanes and silicones, 3-[(2-aminoethyl) amino]propyl 
Me, di-Me, reaction products with polyethylene-polypropylene glycol Bu 
glycidyl ether.
CAS number: 189354-73-2.
Basis for action: The PMN substance will be used as an ingredient for 
plastic resins. Based on structural activity analogy to similar 
substances, EPA is concerned that lung toxicity will occur in exposed 
workers. EPA determined that use of the substance did not present an 
unreasonable risk because significant worker exposure would not occur. 
EPA has determined that applications generating an aerosol, mist, or 
vapor may result in significant worker exposure. Based on this 
information the PMN substance meets the concern criteria at 
Sec. 721.170(b)(3)(ii).
Recommended testing: EPA has determined that a 90-day oral subchronic 
toxicity study in rats (40 CFR 798.2650 or OPPTS 870.3100 test 
guideline (63 FR 41845, August 5, 1998) (FRL-5740-1)) would help to 
characterize the health effects of the PMN substance.
CFR citation: 40 CFR 721.9516.

PMN Number P-97-813

Chemical name: (generic) Diphenol tars.
CAS number: Not available.
Basis for action: The PMN substance will be used as a polymer additive. 
Based on structural activity analogy to phenols, EPA is concerned that 
toxicity to aquatic organisms may occur at a concentration as low as 10 
ppb of the PMN substance in surface waters. EPA determined that use of 
the substance as described in the PMN did not present an unreasonable 
risk because the substances would not be released to surface waters in 
significant quantities. EPA has determined that other uses of the 
substance may result in releases to surface waters during use which 
exceed the concern concentration. Based on this information the PMN 
substance meet the concern criteria at Sec. 721.170(b)(4)(ii).
Recommended testing: EPA has determined that a fish acute toxicity 
study (40 CFR 797.1400 or OPPTS 850.1075 test guideline (public draft; 
61 FR 16486, April 15, 1996) (FRL-5363-1)), a daphnid acute toxicity 
study (40 CFR 797.1300 or OPPTS 850.1010 test guideline (public draft; 
61 FR 16486, April 15, 1996) (FRL-5363-1)), and an algal acute toxicity 
study (40 CFR 797.1050 or OPPTS 850.5400 test

[[Page 44568]]

guideline (public draft; 61 FR 16486, April 15, 1996) (FRL-5363-1)) 
would help characterize the environmental effects of the PMN substance.
CFR citation: 40 CFR 721.9661.

PMN Number P-97-820

Chemical name: (generic) C.I. Disperse Red 152.
CAS number: Not available.
Basis for action: The PMN substance will be used as a dyestuff for 
fabrics. Based on analogy to structurally similar substances, EPA is 
concerned that cancer and developmental toxicity will occur in exposed 
workers. EPA determined that use of the substance did not present an 
unreasonable risk because significant worker exposure would not occur. 
EPA has determined that use of the substance as a powder may result in 
significant worker exposure. Based on this information the PMN 
substance meets the concern criteria at Sec. 721.170 (b)(1)(i)(D) and 
(b)(3)(ii).
Recommended testing: EPA has determined that a prenatal developmental 
toxicity test by the oral route in two-species (40 CFR 799.9370) (62 FR 
43832, August 15, 1997) (FRL-5719-5) and a two-species oral 
carcinogenicity study (40 CFR 799.9420) (62 FR 43838, August 15, 1997) 
(FRL-5719-5) would help to characterize the health effects of the PMN 
substance.
CFR citation: 40 CFR 721.2580.

PMN Numbers P-97-854

Chemical name: (generic) 3,6-Bis(dialkylamino)-9-[2-
alkoxycarbonyl)phenyl]-xanthylium salt,.
CAS number: Not available.
Basis for action: The PMN substance will be used as a colorant 
additive. Based on structural activity analogy to cationic dyes, EPA is 
concerned that toxicity to aquatic organisms may occur at a 
concentration as low as 2 ppb of the PMN substance in surface waters. 
EPA determined that use of the substance as described in the PMN did 
not present an unreasonable risk because the substance would not be 
released to surface waters in significant quantities. EPA has 
determined that other uses of the substance may result in releases to 
surface waters which exceed the concern concentration. Based on this 
information the PMN substance meets the concern criteria at 
Sec. 721.170(b)(4)(ii).
Recommended testing: EPA has determined that an activated sludge 
sorption isotherm (OPPTS 835.1110 test guideline (63 FR 4259, January 
28, 1998) (FRL-5761-7)), an algal acute toxicity study (40 CFR 797.1050 
or OPPTS 850.5400 test guideline (public draft; 61 FR 16486, April 15, 
1996) (FRL-5363-1)), a chronic 60-day fish early life stage toxicity 
test in rainbow trout (40 CFR 797.1600 or OPPTS 850.1400 test guideline 
(public draft; 61 FR 16486, April 15, 1996) (FRL-5363-1)), and a 21-day 
daphnid chronic toxicity test (40 CFR 797.1330 or OPPTS 850.1300 test 
guideline (public draft; 61 FR 16486, April 15, 1996) (FRL-5363-1)) 
would help characterize the environmental effects of the PMN substance.
CFR citation: 40 CFR 721.9969.

PMN Numbers P-97-869/870/871

Chemical name: (generic) Alkylated diphenyls.
CAS number: Not available.
Basis for action: The PMN substances will be used as specialty 
solvents. Based on structural activity analogy to similar substances, 
EPA is concerned that toxicity to aquatic organisms may occur at a 
concentration as low as 1 ppb of the PMN substances in surface waters. 
EPA determined that use of the substances as described in the PMNs did 
not present an unreasonable risk because the substances would not be 
released to surface waters in significant quantities. EPA has 
determined that other uses of the substances may result in releases to 
surface waters which exceed the concern concentration. Based on this 
information the PMN substances meets the concern criteria at 
Sec. 721.170(b)(4)(ii).
Recommended testing: EPA has determined that a fish acute toxicity 
study (40 CFR 797.1400 or OPPTS 850.1075 test guideline (public draft; 
61 FR 16486, April 15, 1996) (FRL-5363-1)), a daphnid acute toxicity 
study (40 CFR 797.1300 or OPPTS 850.1010 test guideline (public draft; 
61 FR 16486, April 15, 1996) (FRL-5363-1)), and an algal acute toxicity 
study (40 CFR 797.1050 or OPPTS 850.5400 test guideline (public draft; 
61 FR 16486, April 15, 1996) (FRL-5363-1)) would help characterize the 
environmental effects of the PMN substances.
CFR citation: 40 CFR 721.2570.

PMN Number P-97-878

Chemical name: (generic) Polysubstituted carbomonocyclic hydroxylamine.
CAS number: Not available.
Basis for action: The PMN substance will be used as an antioxidant. 
Based on analogy to structurally similar substances, there is concern 
for liver toxicity, kidney toxicity, developmental toxicity, and 
neurotoxicity. EPA determined that use of the substance as described in 
the PMN did not present an unreasonable risk because significant worker 
exposure would not result if respiratory protection were used by 
workers. EPA has determined that manufacture, processing, or use of the 
substance without respiratory protection may result in significant 
inhalation exposure to workers. Based on this information the PMN 
substance meets the concern criteria at Sec. 721.170(b)(3)(ii).
Recommended testing: EPA has determined that a 90-day oral subchronic 
toxicity study in rats (40 CFR 798.2650 or OPPTS 870.3100 test 
guideline (63 FR 41845, August 5, 1998) (FRL-5740-1)) and a prenatal 
developmental toxicity study by the oral route in two-species (40 CFR 
799.9370) (62 FR 43832, August 15, 1997) (FRL-5719-5) would 
characterize the human health effects of the PMN substance.
CFR citation: 40 CFR 721.2083.

PMN Numbers P-97-880/881/882

Chemical name: (generic) Alkylphenylpolyetheralkanolamines.
CAS number: Not available.
Basis for action: The PMN substances will be used as a fuel additive. 
Based on structural activity analogy to aliphatic amines, EPA is 
concerned that toxicity to aquatic organisms may occur at a 
concentration as low as 1 ppb of the PMN substances in surface waters. 
EPA determined that use of the substances as described in the PMN did 
not present an unreasonable risk because the substances would not be 
released to surface waters. EPA has determined that other uses of the 
substances may result in releases to surface waters which exceed the 
concern concentration. Based on this information the PMN substances 
meets the concern criteria at Sec. 721.170(b)(4)(ii).
Recommended testing: EPA has determined that a fish acute toxicity 
study (40 CFR 797.1400 or OPPTS 850.1075 test guideline (public draft; 
61 FR 16486, April 15, 1996) (FRL-5363-1)), a daphnid acute toxicity 
study (40 CFR 797.1300 or OPPTS 850.1010 test guideline (public draft; 
61 FR 16486, April 15, 1996) (FRL-5363-1)), and an algal acute toxicity 
study (40 CFR 797.1050 or OPPTS 850.5400 test guideline (public draft; 
61 FR 16486, April 15, 1996) (FRL-5363-1)) would help characterize the 
environmental effects of the PMN substances.
CFR citation: 40 CFR 721.435.

PMN Numbers P-97-943/944/945/946/947/948

Chemical name: (generic) Mixed trialkylamines.
CAS number: Not available.
Basis for action: The PMN substances will be used as dispersing agents,

[[Page 44569]]

surfactants, and manufacturing intermediates. Based on structural 
activity analogy to aliphatic amines, EPA is concerned that toxicity to 
aquatic organisms may occur at a concentration as low as 1 ppb of the 
PMN substances in surface waters. EPA determined that use of these 
substances as described in the PMN did not present an unreasonable risk 
because the submitter has agreed to recommend ``no releases to water'' 
in its Material Safety Data Sheet (MSDS). EPA has determined that other 
uses of these substances may result in releases to surface waters which 
exceed the concern concentration. Based on this information the PMN 
substances meets the concern criteria at Sec. 721.170(b)(4)(ii).
Recommended testing: EPA has determined that a fish acute toxicity 
study (40 CFR 797.1400 or OPPTS 850.1075 test guideline (public draft; 
61 FR 16486, April 15, 1996) (FRL-5363-1)), a daphnid acute toxicity 
study (40 CFR 797.1300 or OPPTS 850.1010 test guideline (public draft; 
61 FR 16486, April 15, 1996) (FRL-5363-1)), and an algal acute toxicity 
study (40 CFR 797.1050 or OPPTS 850.5400 test guideline (public draft; 
61 FR 16486, April 15, 1996) (FRL-5363-1)) would help characterize the 
environmental effects of the PMN substances.
CFR citation: 40 CFR 721.9685.

PMN Number P-97-956

Chemical name: (generic) Mixed metal oxide.
CAS number: Not available.
Basis for action: The PMN substance will be used as a pearlescent 
pigment. Based on analogy to structurally similar substances, there is 
concern for lung toxicity and fibrosis. EPA determined that use of the 
substance as described in the PMN did not present an unreasonable risk 
because significant worker exposure would not result if respiratory 
protection were used by workers. EPA has determined that manufacture, 
processing, or use of the substance without respiratory protection may 
result in significant inhalation exposure to workers. Based on this 
information the PMN substance meets the concern criteria at 
Sec. 721.170(b)(3)(ii).
Recommended testing: EPA has determined that a 90-day subchronic 
inhalation study (40 CFR 799.9346) (62 FR 43828, August 15, 1997) (FRL-
5719-5) would characterize the human health effects of the PMN 
substance.
CFR citation: 40 CFR 721.5548.

PMN Number P-97-1011

Chemical name: Oxirane, 2,2'-[methylenebis [(2,6-dimethyl-4,1-
phenylene) oxymethylene]]bis-.
CAS number: 93705-66-9.
Effective date of section 5(e) consent order: January 15, 1998.
Basis for section 5(e) consent order: The order was issued under 
section 5(e)(1)(A)(i) and (e)(1)(A)(ii)(I) of TSCA based on a finding 
that the substance may present an unreasonable risk of injury to health 
and the environment.
Toxicity concern: Structurally similar chemicals have been shown to 
cause cancer and reproductive effects in test animals and toxicity to 
aquatic organisms.
Recommended testing: EPA has determined that a 90-day subchronic 
inhalation study in rats with attention to pathology of the 
reproductive organs (40 CFR 799.9346) (62 FR 43828, August 15,1997) 
(FRL-5719-5) and a two-species carcinogenicity study (40 CFR 799.9420) 
(62 FR 43838, August 15, 1997) (FRL-5719-5) would help to characterize 
health effects. EPA has determined that a fish acute toxicity study (40 
CFR 797.1400 or OPPTS 850.1075 test guideline (public draft; 61 FR 
16486, April 15, 1996) (FRL-5363-1)), a daphnid acute toxicity study 
(40 CFR 797.1300 or OPPTS 850.1010 test guideline (public draft; 61 FR 
16486, April 15, 1996) (FRL-5363-1)), and an algal acute toxicity study 
(40 CFR 797.1050 or OPPTS 850.5400 test guideline (public draft; 61 FR 
16486, April 15, 1996) (FRL-5363-1)) would help characterize the 
environmental effects of the PMN substance. The PMN submitter has 
agreed not to exceed the production volume limit without performing the 
90-day subchronic inhalation toxicity test.
CFR citation: 40 CFR 721.5580.

PMN Numbers P-97-1028/1029

Chemical name: (generic) Substituted nitrobenzene (P-97-1028); 
(generic) Substituted benzonitrile (P-97-1029).
CAS number: Not available.
Basis for action: The PMN substances will be used as described in the 
PMNs. Based on analogy to structurally similar substances, there is 
concern for mutagenicity, carcinogenicity, immunotoxicity, liver 
toxicity, kidney toxicity, reproductive/developmental toxicity, and 
neurotoxicity. EPA determined that use of the substances as described 
in the PMNs did not present an unreasonable risk because significant 
worker exposure would not result if respiratory protection and 
impervious gloves were used by workers. EPA has determined that 
manufacture, processing, or use of the substances without respiratory 
and dermal protection may result in significant inhalation and dermal 
exposure to workers. Based on this information the PMN substances meet 
the concern criteria at Sec. 721.170(b)(3)(ii).
Recommended testing: EPA has determined that a skin sensitization test 
in Guinea pigs (40 CFR 798.4100 or OPPTS 870.2600 test guideline (63 FR 
41845, August 5, 1998) (FRL-5740-1)), a Salmonella assay (40 CFR 
798.5625 or OPPTS 870.5265 test guideline (63 FR 41845, August 5, 1998) 
(FRL-5740-1)), a mouse micronucleus assay by intraperitoneal injection 
(40 CFR 799.9539) (62 FR 43853, August 15, 1997) (FRL-5719-5), a 
neurotoxicity screening battery, National Technical Information Service 
(NTIS) Publication 91-154617, March 1991, series 81-8, 82-7, 831 
(emphasizes the automated measuring of motor activity which was seen to 
be a sensitive end point for several analogues), an Organization for 
Economic Cooperation and Development (OECD) guideline no. 421, 
reproductive/ developmental toxicity screening test (for initial 
information on all aspects of reproductive/developmental toxicity), a 
28-day repeated oral exposure test in species to determine liver/kidney 
toxicity (40 CFR 798.4900 or OPPTS 870.3700 test guideline (63 FR 
41845, August 5, 1998) (FRL-5740-1)), and a two-species carcinogenicity 
study (40 CFR 799.9420) (62 FR 43838, August 15, 1997) (FRL- 5719-5) 
would help characterize the health effects of the PMN substances.
CFR citations: 40 CFR 721.5360 (P-97-1028); 40 CFR 721.1734 (P-97-
1029).

PMN Number P-97-1046

Chemical name: (generic) Substituted S-phenylthiazole.
CAS number: Not available.
Basis for action: The PMN substance will be used as a pesticide 
intermediate. Based on submitted test data for a structurally similar 
substance, EPA is concerned that the PMN substance may cause 
hepatotoxicity, kidney toxicity, reproductive toxicity, blood toxicity, 
developmental toxicity, and toxicity to the spleen and adrenal glands. 
Based on structural activity analogy to aliphatic amines, EPA is 
concerned that toxicity to aquatic organisms may occur at a 
concentration as low as 40 ppb of the PMN substance in surface waters. 
EPA determined that use of the substance as described in the PMN did 
not present an unreasonable risk because there were no significant 
worker or environmental exposures. EPA has determined that domestic 
manufacture of the PMN substance may result in significant

[[Page 44570]]

worker or environmental exposures. Based on this information the PMN 
substance meets the concern criteria at Sec. 721.170 (b)(3)(ii) and 
(b)(4)(ii).
Recommended testing: EPA has determined that a 90-day subchronic oral 
study in rats (40 CFR 798.2650 or OPPTS 870.3100 test guideline (63 FR 
41845, August 5, 1998) (FRL-5740-1)), a prenatal developmental toxicity 
study by the oral route in two-species (40 CFR 799.9370) (62 FR 43832, 
August 15, 1997) (FRL-5719-5), and a reproduction and fertility effects 
study by the oral route (40 CFR 799.9380) (62 FR 43834, August 15, 
1997) (FRL-5719-5) would help characterize the health effects of the 
PMN substance. EPA has also determined that a fish acute toxicity study 
(40 CFR 797.1400 or OPPTS 850.1075 test guideline (public draft; 61 FR 
16486, April 15, 1996) (FRL-5363-1)), a daphnid acute toxicity study 
(40 CFR 797.1300 or OPPTS 850.1010 test guideline (public draft; 61 FR 
16486, April 15, 1996) (FRL-5363-1)), and an algal acute toxicity study 
(40 CFR 797.1050 or OPPTS 850.5400 test guideline (public draft; 61 FR 
16486, April 15, 1996) (FRL-5363-1)) would help characterize the 
environmental effects of the PMN substance.
CFR citation: 40 CFR 721.5965.

PMN Numbers P-97-1060/1061/1062

Chemical name: (generic) Sodium salts of dodecylphenol.
CAS number: Not available.
Basis for action: The PMN substances will be used as catalysts. Based 
on structural activity analogy to phenols, EPA is concerned that 
toxicity to aquatic organisms may occur at a concentration as low as 1 
ppb of the PMN substances in surface waters. EPA determined that use of 
the substances as described in the PMNs did not present an unreasonable 
risk because the substances would not be released to surface waters in 
significant quantities. EPA has determined that other uses of the 
substances may result in releases to surface waters which exceed the 
concern concentration. Based on this information the PMN substances 
meets the concern criteria at Sec. 721.170(b)(4)(ii).
Recommended testing: EPA has determined that a fish acute toxicity 
study (40 CFR 797.1400 or OPPTS 850.1075 test guideline (public draft; 
61 FR 16486, April 15, 1996) (FRL-5363-1)), a daphnid acute toxicity 
study (40 CFR 797.1300 or OPPTS 850.1010 test guideline (public draft; 
61 FR 16486, April 15, 1996) (FRL-5363-1)), and an algal acute toxicity 
study (40 CFR 797.1050 or OPPTS 850.5400 test guideline (public draft; 
61 FR 16486, April 15, 1996) (FRL-5363-1)) would help characterize the 
environmental effects of the PMN substances.
CFR citation: 40 CFR 721.2585.

PMN Number P-97-1095

Chemical name: (generic) Substituted alkyl aminomethylene 
polyphosphonic acid, salt.
CAS number: Not available.
Basis for action: The PMN substance will be used as a processing aid. 
Based on structural activity analogy to aliphatic amines, EPA is 
concerned that toxicity to aquatic organisms may occur at a 
concentration as low as 200 ppb of the PMN substance in surface waters. 
EPA determined that use of the substance as described in the PMN did 
not present an unreasonable risk because the substance would not be 
released to surface waters. EPA has determined that other uses of the 
substance may result in releases to surface waters which exceed the 
concern concentration. Based on this information the PMN substance 
meets the concern criteria at Sec. 721.170(b)(4)(ii).
Recommended testing: EPA has determined that a fish acute toxicity 
study (40 CFR 797.1400 or OPPTS 850.1075 test guideline (public draft; 
61 FR 16486, April 15, 1996) (FRL-5363-1)), a daphnid acute toxicity 
study (40 CFR 797.1300 or OPPTS 850.1010 test guideline (public draft; 
61 FR 16486, April 15, 1996) (FRL-5363-1)), and an algal acute toxicity 
study (40 CFR 797.1050 or OPPTS 850.5400 test guideline (public draft; 
61 FR 16486, April 15, 1996) (FRL-5363-1)) would help characterize the 
environmental effects of the PMN substance.
CFR citation: 40 CFR 721.7785.

PMN Number P-98-24

Chemical name: (generic) Methoxy benzoic acid derivative.
CAS number: Not available.
Basis for action: The PMN substance will be used as a mediator in 
enzyme catalyzed reactions. Based on submitted test data, EPA is 
concerned that toxicity to aquatic organisms may occur at a 
concentration as low as 40 ppb of the PMN substance in surface waters. 
EPA determined that use of the substance as described in the PMN did 
not present an unreasonable risk because the substance would not be 
released to surface waters in significant quantities. EPA has 
determined that other uses of the substance may result in releases to 
surface waters which exceed the concern concentration. Based on this 
information the PMN substance meets the concern criteria at 
Sec. 721.170(b)(4)(i).
Recommended testing: EPA has determined that a chronic 60-day fish 
early life stage toxicity test in rainbow trout (40 CFR 797.1600 or 
OPPTS 850.1400 test guideline (public draft; 61 FR 16486, April 15, 
1996) (FRL-5363-1)) and a 21-day daphnid chronic toxicity test (40 CFR 
797.1330 or OPPTS 850.1300 test guideline (public draft; 61 FR 16486, 
April 15, 1996) (FRL-5363-1)) would help characterize the environmental 
effects of the PMN substance.
CFR citation: 40 CFR 721.1710

PMN Number P-98-45

Chemical name: (generic) Dialkylaminophenyl imino pyrazole acid ester.
CAS number: Not available.
Basis for action: The PMN substance will be used as a colorant for 
thermal printing. Based on structural activity analogy to esters, EPA 
is concerned that toxicity to aquatic organisms may occur at a 
concentration as low as 30 ppb of the PMN substance in surface waters. 
EPA determined that use of the substance as described in the PMN did 
not present an unreasonable risk because the substance would not be 
released to surface waters. EPA has determined that other uses of the 
substance may result in releases to surface waters which exceed the 
concern concentration. Based on this information the PMN substance 
meets the concern criteria at Sec. 721.170(b)(4)(ii).
Recommended testing: EPA has determined that a fish acute toxicity 
study (40 CFR 797.1400 or OPPTS 850.1075 test guideline (public draft; 
61 FR 16486, April 15, 1996) (FRL-5363-1)), a daphnid acute toxicity 
study (40 CFR 797.1300 or OPPTS 850.1010 test guideline (public draft; 
61 FR 16486, April 15, 1996) (FRL-5363-1)), and an algal acute toxicity 
study (40 CFR 797.1050 or OPPTS 850.5400 test guideline (public draft; 
61 FR 16486, April 15, 1996) (FRL-5363-1)) would help characterize the 
environmental effects of the PMN substance.
CFR citation: 40 CFR 721.987.

PMN Number P-98-91

Chemical name: (generic) Pyrazolone azomethine dye.
CAS number: Not available.
Basis for action: The PMN substance will be used as a colorant for 
thermal printing. Based on submitted test data, EPA is concerned that 
toxicity to aquatic organisms may occur at a concentration as low as 1 
ppb of the PMN substance in surface waters. EPA determined that use of 
the substance as described in the PMN did not present an

[[Page 44571]]

unreasonable risk because the substance would not be released to 
surface waters. EPA has determined that other uses of the substance may 
result in releases to surface waters which exceed the concern 
concentration. Based on this information the PMN substance meets the 
concern criteria at Sec. 721.170(b)(4)(i).
Recommended testing: EPA has determined that a chronic 60-day fish 
early life stage toxicity test in rainbow trout (40 CFR 797.1600 or 
OPPTS 850.1400 test guideline (public draft; 61 FR 16486, April 15, 
1996) (FRL-5363-1)) and a 21-day daphnid chronic toxicity test (40 CFR 
797.1330 or OPPTS 850.1300 test guideline (public draft; 61 FR 16486, 
April 15, 1996) (FRL-5363-1)) would help characterize the environmental 
effects of the PMN substance.
CFR citation: 40 CFR 721.988.

PMN Number P-98-101

Chemical name: 7-Oxabicyclo[4.1.0]heptane-3-carboxylic acid, methyl 
ester.
CAS number: 41088-52-2.
Basis for action: The PMN substance will be used as a chemical 
intermediate. Based on analogy to structurally similar substances and 
toxicity data submitted with the PMN, EPA is concerned that 
mutagenicity, carcinogenicity, reproductive toxicity in males, 
developmental toxicity, irritation to membranes, and sensitization to 
lungs and skin will occur in exposed workers. EPA determined that use 
of the substance as an intermediate did not present an unreasonable 
risk because it did not result in significant worker exposure. EPA has 
determined that use other than as an intermediate may result in 
significant worker exposure. Based on this information the PMN 
substance meets the concern criteria at Sec. 721.170(b)(1)(i)(B), 
(b)(3)(i), and (b)(3)(ii).
Recommended testing: EPA has determined that a 90-day oral subchronic 
toxicity study in rats (40 CFR 798.2650 or OPPTS 870.3100 test 
guideline (63 FR 41845, August 5, 1998) (FRL-5740-1)) and an oral two-
species carcinogenicity study (40 CFR 799.9420) (62 FR 43838, August 
15, 1997) (FRL-5719-5) would help characterize the health effects of 
the PMN substance.
CFR citation: 40 CFR 721.4097.

PMN Number P-98-155

Chemical name: (generic) Disubstituted benzene ether, polymer with 
substituted phenol.
CAS number: Not available.
Basis for action: The PMN substance will be used as a reactant in the 
manufacture of a thermosetting adhesive polymer. Based on structural 
activity analogy to phenols, EPA is concerned that toxicity to aquatic 
organisms may occur at a concentration as low as 1 ppb of the PMN 
substance in surface waters. EPA determined that use of the substance 
as described in the PMN did not present an unreasonable risk because 
the substance would not be released to surface waters. EPA has 
determined that other uses of the substance may result in releases to 
surface waters which exceed the concern concentration. Based on this 
information the PMN substance meets the concern criteria at 
Sec. 721.170(b)(4)(ii).
Recommended testing: EPA has determined that a fish acute toxicity 
study (40 CFR 797.1400 or OPPTS 850.1075 test guideline (public draft; 
61 FR 16486, April 15, 1996) (FRL-5363-1)), a daphnid acute toxicity 
study (40 CFR 797.1300 or OPPTS 850.1010 test guideline (public draft; 
61 FR 16486, April 15, 1996) (FRL-5363-1)), and an algal acute toxicity 
study (40 CFR 797.1050 or OPPTS 850.5400 test guideline (public draft; 
61 FR 16486, April 15, 1996) (FRL-5363-1)) would help characterize the 
environmental effects of the PMN substance.
CFR citation: 40 CFR 721.1580.

PMN Number P-98-185

Chemical name: Ethanol, 2,2'2''-nitrilotris-, compound with alpha-
[2,4,6-tris(1-phenylethyl)phenyl]-omega-hydroxypoly (oxy-1,2-
ethanediyl)-phosphate.
CAS number: 105362-40-1.
Basis for action: The PMN substance will be used as a pesticide inert. 
Based on submitted test data, EPA is concerned that liver toxicity, 
effects to the thyroid and pituitary glands, and effects to the kidneys 
will occur in exposed workers. EPA determined that import of the 
substance for use as a pesticide inert did not present an unreasonable 
risk because it did not result in significant worker exposure. EPA has 
determined that use other than import for use as a pesticide inert may 
result in significant worker exposure. Based on this information the 
PMN substance meets the concern criteria at Sec. 721.170(b)(3)(i).
Recommended testing: EPA has determined that a 2-year oral chronic 
toxicity study in rats (40 CFR 798.3260 or OPPTS 870.4100 test 
guideline (63 FR 41845, August 5, 1998) (FRL-5740-1)) would help 
characterize the health effects of the PMN substance.
CFR citation: 40 CFR 721.5356.

PMN Number P-98-198

Chemical name: Phenol, 5-amino-2,4-dicholoro-, hydrochloride.
CAS number: 197178-93-1.
Basis for action: The PMN substance will have a destructive use. Based 
on structural activity analogy to phenols and anilines, EPA is 
concerned that toxicity to aquatic organisms may occur at a 
concentration as low as 2 ppb of the PMN substance in surface waters. 
Based on structural activity analogy to halogenated benzenes, phenols, 
and anilines EPA is concerned for potential liver toxicity, kidney 
toxicity, developmental toxicity, neurotoxicity, carcinogenicity, blood 
toxicity, immunotoxicity, and irritation to skin, eyes, and mucous 
membranes. EPA determined that use of the substance as described in the 
PMN did not present an unreasonable risk because the substance would 
not be released to surface waters and workers would not be exposed via 
inhalation. EPA has determined that other uses of the substance may 
result in releases to surface waters which exceed the concern 
concentration and inhalation exposure to workers. Based on this 
information the PMN substance meets the concern criteria at 
Sec. 721.170(b)(1)(i)(C), (b)(3)(ii), and (b)(4)(ii).
Recommended testing: EPA has determined that a fish acute toxicity 
study (40 CFR 797.1400 or OPPTS 850.1075 test guideline (public draft; 
61 FR 16486, April 15, 1996) (FRL-5363-1)), a daphnid acute toxicity 
study (40 CFR 797.1300 or OPPTS 850.1010 test guideline (public draft; 
61 FR 16486, April 15, 1996) (FRL-5363-1)), and an algal acute toxicity 
study (40 CFR 797.1050 or OPPTS 850.5400 test guideline (public draft; 
61 FR 16486, April 15, 1996) (FRL-5363-1)) would help characterize the 
environmental effects of the PMN substance. EPA has also determined 
that a 90-day oral subchronic toxicity study in rats (40 CFR 798.2650 
or OPPTS 870.3100 test guideline (63 FR 41845, August 5, 1998) (FRL-
5740-1)), a prenatal developmental toxicity study by the oral route in 
two-species (40 CFR 799.9370) (62 FR 43832, August 15, 1997) (FRL-5719-
5) and an oral two-species carcinogenicity study (40 CFR 799.9420) (62 
FR 43838, August 15, 1997) (FRL-5719-5) would help characterize the 
health effects of the PMN substance.
CFR citation: 40 CFR 721.5775.

PMN Numbers P-98-412/414/415/416/417

Chemical names: (generic) Coco alkyldimethyl amine salts.
CAS number: Not available.

[[Page 44572]]

Basis for action: The PMN substances will be used as a component of a 
coating. Based on submitted test data, EPA is concerned that toxicity 
to aquatic organisms may occur at a concentration as low as 1 ppb of 
the PMN substances in surface waters. EPA determined that use of the 
substances as described in the PMN did not present an unreasonable risk 
because the substances would not be released to surface waters. EPA has 
determined that other uses of the substances may result in releases to 
surface waters which exceed the concern concentration. Based on this 
information the PMN substances meet the concern criteria at 
Sec. 721.170(b)(4)(ii).
Recommended testing: EPA has determined that a fish acute toxicity 
study (40 CFR 797.1400 or OPPTS 850.1075 test guideline (public draft; 
61 FR 16486, April 15, 1996) (FRL-5363-1)), a daphnid acute toxicity 
study (40 CFR 797.1300 or OPPTS 850.1010 test guideline (public draft; 
61 FR 16486, April 15, 1996) (FRL-5363-1)), and an algal acute toxicity 
study (40 CFR 797.1050 or OPPTS 850.5400 test guideline (public draft; 
61 FR 16486, April 15, 1996) (FRL-5363-1)) would help characterize the 
environmental effects of the PMN substances.
CFR citation: 40 CFR 721.9490.

IV. Objectives and Rationale of the Rule

    During review of the PMNs submitted for the chemical substances 
that are subject to this SNUR, EPA concluded that for 12 of the 73 
substances, regulation was warranted under section 5(e) of TSCA, 
pending the development of information sufficient to make reasoned 
evaluations of the health or environmental effects of the substances. 
The basis for such findings is outlined in Unit III. of this preamble. 
Based on these findings, TSCA section 5(e) consent orders requiring the 
use of appropriate exposure controls were negotiated with the PMN 
submitters; the SNUR provisions for these substances designated herein 
are consistent with the provisions of the TSCA section 5(e) consent 
orders.
    In the other 61 cases for which the proposed uses are not regulated 
under a TSCA section 5(e) consent order, EPA determined that one or 
more of the criteria of concern established at 40 CFR 721.170 were met.
    EPA is issuing this SNUR for specific chemical substances which 
have undergone premanufacture review to ensure that:
    (1) EPA will receive notice of any company's intent to manufacture, 
import, or process a listed chemical substance for a significant new 
use before that activity begins.
    (2) EPA will have an opportunity to review and evaluate data 
submitted in a SNUR notice before the notice submitter begins 
manufacturing, importing, or processing a listed chemical substance for 
a significant new use.
    (3) When necessary, to prevent unreasonable risks, EPA will be able 
to regulate prospective manufacturers, importers, or processors of a 
listed chemical substance before a significant new use of that 
substance occurs.
    (4) All manufacturers, importers, and processors of the same 
chemical substance which is subject to a TSCA section 5(e) consent 
order are subject to similar requirements.
    Issuance of a SNUR for a chemical substance does not signify that 
the substance is listed on the TSCA Inventory. Manufacturers, 
importers, and processors are responsible for ensuring that a new 
chemical substance subject to a final SNUR is listed on the TSCA 
Inventory.

V. Direct Final Procedures

    EPA is issuing these SNURs as direct final rules, as described in 
40 CFR 721.160(c)(3) and 721.170(d)(4). In accordance with 40 CFR 
721.160(c)(3)(ii), this rule will be effective October 19, 1998, unless 
EPA receives a written notice by September 21, 1998 that someone wishes 
to make adverse or critical comments on EPA's action. If EPA receives 
such a notice, EPA will publish a notice to withdraw the direct final 
SNUR for the specific substance to which the adverse or critical 
comments apply. EPA will then propose a SNUR for the specific substance 
providing a 30-day comment period.
    This action establishes SNURs for a number of chemical substances. 
Any person who submits a notice of intent to submit adverse or critical 
comments must identify the substance and the new use to which it 
applies. EPA will not withdraw a SNUR for a substance not identified in 
a notice.

VI. Test Data and Other Information

    EPA recognizes that section 5 of TSCA does not require developing 
any particular test data before submission of a SNUN. Persons are 
required only to submit test data in their possession or control and to 
describe any other data known to or reasonably ascertainable by them. 
In cases where a TSCA section 5(e) consent order requires or recommends 
certain testing, Unit III. of this preamble lists those recommended 
tests.
    However, EPA has established production limits in the TSCA section 
5(e) consent orders for several of the substances regulated under this 
rule, in view of the lack of data on the potential health and 
environmental risks that may be posed by the significant new uses or 
increased exposure to the substances. These production limits cannot be 
exceeded unless the PMN submitter first submits the results of toxicity 
tests that would permit a reasoned evaluation of the potential risks 
posed by these substances. Under recent consent orders, each PMN 
submitter is required to submit each study at least 14 weeks (earlier 
consent orders required submissions at least 12 weeks) before reaching 
the specified production limit. Listings of the tests specified in the 
TSCA section 5(e) consent orders are included in Unit III. of this 
preamble. The SNURs contain the same production volume limits as the 
consent orders. Exceeding these production limits is defined as a 
significant new use.
    The recommended studies may not be the only means of addressing the 
potential risks of the substance. However, SNUNs submitted for 
significant new uses without any test data may increase the likelihood 
that EPA will take action under TSCA section 5(e), particularly if 
satisfactory test results have not been obtained from a prior 
submitter. EPA recommends that potential SNUN submitters contact EPA 
early enough so that they will be able to conduct the appropriate 
tests.
    SNUN submitters should be aware that EPA will be better able to 
evaluate SNUNs which provide detailed information on:
    (1) Human exposure and environmental release that may result from 
the significant new use of the chemical substances.
    (2) Potential benefits of the substances.
    (3) Information on risks posed by the substances compared to risks 
posed by potential substitutes.

VII. Procedural Determinations

    EPA is establishing through this rule some significant new uses 
which have been claimed as CBI subject to Agency confidentiality 
regulations at 40 CFR part 2. EPA is required to keep this information 
confidential to protect the CBI of the original PMN submitter. EPA 
promulgated a procedure to deal with the situation where a specific 
significant new use is CBI. This procedure appears in 40 CFR 
721.1725(b)(1) and is similar to that in Sec. 721.11 for situations 
where the chemical identity of the substance subject to a SNUR is CBI. 
This

[[Page 44573]]

procedure is cross-referenced in each of these SNURs.
    A manufacturer or importer may request EPA to determine whether a 
proposed use would be a significant new use under this rule. Under the 
procedure incorporated from Sec. 721.1725(b)(1), a manufacturer or 
importer must show that it has a bona fide intent to manufacture or 
import the substance and must identify the specific use for which it 
intends to manufacture or import the substance. If EPA concludes that 
the person has shown a bona fide intent to manufacture or import the 
substance, EPA will tell the person whether the use identified in the 
bona fide submission would be a significant new use under the rule. 
Since most of the chemical identities of the substances subject to 
these SNURs are also CBI, manufacturers and processors can combine the 
bona fide submission under the procedure in Sec. 721.1725(b)(1) with 
that under Sec. 721.11 into a single step.
    If a manufacturer or importer is told that the production volume 
identified in the bona fide submission would not be a significant new 
use, i.e. it is below the level that would be a significant new use, 
that person can manufacture or import the substance as long as the 
aggregate amount does not exceed that identified in the bona fide 
submission to EPA. If the person later intends to exceed that volume, a 
new bona fide submission would be necessary to determine whether that 
higher volume would be a significant new use. EPA is considering 
whether to adopt a special procedure for use when CBI production volume 
is designated as a significant new use. Under such a procedure, a 
person showing a bona fide intent to manufacture or import the 
substance, under the procedure described in Sec. 721.11, would 
automatically be informed of the production volume that would be a 
significant new use. Thus, the person would not have to make multiple 
bona fide submissions to EPA for the same substance to remain in 
compliance with the SNUR, as could be the case under the procedures in 
Sec. 721.1725(b)(1).

VIII. Applicability of Rule to Uses Occurring Before Effective Date 
of the Final Rule

    To establish a significant ``new'' use, EPA must determine that the 
use is not ongoing. The chemical substances subject to this rule have 
recently undergone premanufacture review. TSCA section 5(e) consent 
orders have been issued for 12 substances and notice submitters are 
prohibited by the TSCA section 5(e) consent orders from undertaking 
activities which EPA is designating as significant new uses. In cases 
where EPA has not received an NOC and the substance has not been added 
to the Inventory, no other person may commence such activities without 
first submitting a PMN. For substances for which an NOC has not been 
submitted at this time, EPA has concluded that the uses are not 
ongoing. However, EPA recognizes in cases when chemical substances 
identified in this SNUR are added to the Inventory prior to the 
effective date of the rule, the substances may be manufactured, 
imported, or processed by other persons for a significant new use as 
defined in this rule before the effective date of the rule. However, 63 
of the 73 substances contained in this rule have CBI chemical 
identities, and since EPA has received a limited number of post-PMN 
bona fide submissions, the Agency believes that it is highly unlikely 
that any of the significant new uses described in the following 
regulatory text are ongoing.
    As discussed in the Federal Register of April 24, 1990 (55 FR 
17376), EPA has decided that the intent of section 5(a)(1)(B) of TSCA 
is best served by designating a use as a significant new use as of the 
date of publication rather than as of the effective date of the rule. 
Thus, persons who begin commercial manufacture, import, or processing 
of the substances regulated through this SNUR will have to cease any 
such activity before the effective date of this rule. To resume their 
activities, these persons would have to comply with all applicable SNUR 
notice requirements and wait until the notice review period, including 
all extensions, expires.
    EPA has promulgated provisions to allow persons to comply with this 
SNUR before the effective date. If a person were to meet the conditions 
of advance compliance under Sec. 721.45(h), the person would be 
considered to have met the requirements of the final SNUR for those 
activities. If persons who begin commercial manufacture, import, or 
processing of the substance between publication and the effective date 
of the SNUR do not meet the conditions of advance compliance, they must 
cease that activity before the effective date of the rule. To resume 
their activities, these persons would have to comply with all 
applicable SNUR notice requirements and wait until the notice review 
period, including all extensions, expires.

IX. Economic Analysis

    EPA has evaluated the potential costs of establishing significant 
new use notice requirements for potential manufacturers, importers, and 
processors of the chemical substances subject to this rule. EPA's 
complete economic analysis is available in the rulemaking record for 
this rule (OPPTS-50632).

X. Public Record and Electronic Submissions

    The official record for this rulemaking, as well as the public 
version, has been established for this rulemaking under docket control 
number OPPTS-50632 (including comments and data submitted 
electronically as described below). A public version of this record, 
including printed, paper versions of electronic comments, which does 
not include any information claimed as CBI is available for inspection 
from 12 noon to 4 p.m., Monday through Friday, excluding legal 
holidays. The official rulemaking record is located in the TSCA 
Nonconfidential Information Center Rm. NE-B607, 401 M St., SW., 
Washington, DC.
    Electronic comments can be sent directly to EPA at:
    [email protected]


    Electronic comments must be submitted as an ASCII file avoiding the 
use of special characters and any form of encryption. Comments and data 
will also be accepted on disks in WordPerfect 5.1/6.1 or ASCII file 
format. All comments and data in electronic form must be identified by 
the docket control number OPPTS-50632. Electronic comments on this rule 
may be filed online at many Federal Depository Libraries.
    The OPPTS harmonized test guidelines referenced in this document 
are available on EPA's World Wide Web site (http://www.epa.gov/
epahome/research.htm) under the heading ``Test Methods and Guidelines/
OPPTS Harmonized Test Guidelines.''

XI. Regulatory Assessment Requirements

    Under Executive Order 12866, entitled Regulatory Planning and 
Review (58 FR 51735, October 4, 1993), this action is not a 
``significant regulatory action'' subject to review by the Office of 
Management and Budget (OMB). In addition, this action does not impose 
any enforceable duty or contain any unfunded mandate as described in 
the Unfunded Mandates Reform Act (UMRA) of 1995 (Pub. L. 104-4), or 
require prior consultation with State officials as also specified in 
Executive Order 12875, entitled Enhancing the Intergovernmental 
Partnership (58 FR 58093, October 28, 1993). Nor does it involve 
special considerations of

[[Page 44574]]

environmental justice related issues as required by Executive Order 
12898, entitled Federal Actions to Address Environmental Justice in 
Minority Populations and Low-Income Populations (59 FR 7629, February 
16, 1994), or additional OMB review in accordance with Executive Order 
13045, entitled Protection of Children from Environmental Health Risks 
and Safety Risks (62 FR 19885, April 23, 1997).
    According to the Paperwork Reduction Act (PRA), 44 U.S.C. 3501 et 
seq., an agency may not conduct or sponsor, and a person is not 
required to respond to a collection of information that requires OMB 
approval under the PRA, unless it has been approved by OMB and displays 
a currently valid OMB control number. The OMB control numbers for EPA's 
regulations, after initial display in the preamble of the final rules, 
are listed in 40 CFR part 9. The information collection requirements 
related to this action have already been approved by OMB pursuant to 
the PRA under OMB control number 2070-0012 (EPA ICR No. 574). This 
action does not impose any burden requiring additional OMB approval.
    If an entity were to submit a significant new use notice to the 
Agency, the annual burden is estimated to average between 30 and 170 
hours per response. This burden estimate includes the time needed to 
review instructions, search existing data sources, gather and maintain 
the data needed, and complete, review and submit the required 
significant new use notice.
    Send any comments about the accuracy of the burden estimate, and 
any suggested methods for minimizing respondent burden, including 
through the use of automated collection techniques, to the Director, 
OPPE Regulatory Information Division, Environmental Protection Agency 
(Mail Code 2137), 401 M St., SW., Washington, DC 20460, with a copy to 
the Office of Information and Regulatory Affairs, Office of Management 
and Budget, 725 17th St., NW., Washington, DC 20503, marked 
``Attention: Desk Officer for EPA.'' Please remember to include the OMB 
control number in any correspondence, but do not submit any completed 
forms to these addresses.
    In addition, pursuant to section 605(b) of the Regulatory 
Flexibility Act (RFA) (5 U.S.C. 601 et seq.), the Agency has previously 
certified, as a generic matter, that the promulgation of a SNUR does 
not have a significant adverse economic impact on a substantial number 
of small entities. The Agency's generic certification for promulgation 
of new SNURs appears on June 2, 1997 (62 FR 29684) (FRL-5597-1) and was 
provided to the Chief Counsel for Advocacy of the Small Business 
Administration.

XII. Submission to Congress and the Comptroller General

    The Congressional Review Act, 5 U.S.C. 801 et seq., as added by the 
Small Business Regulatory Enforcement Fairness Act of 1996, generally 
provides that before a rule may take effect, the agency promulgating 
the rule must submit a rule report, which includes a copy of the rule, 
to each House of the Congress and to the Comptroller General of the 
United States. EPA will submit a report containing this rule and other 
required information to the U.S. Senate, the U.S. House of 
Representatives, and the Comptroller General of the United States prior 
to publication of the rule in the Federal Register. This rule is not a 
``major rule'' as defined by 5 U.S.C. 804(2).

List of Subjects in 40 CFR Part 721

    Environmental protection, Chemicals, Hazardous substances, 
Reporting and recordkeeping requirements.

    Dated: August 10, 1998.

Ward Penberthy,

Acting Director, Chemical Control Division, Office of Pollution 
Prevention and Toxics.

    Therefore, 40 CFR part 721 is amended as follows:

PART 721--[AMENDED]

    1. The authority citation for part 721 continues to read as 
follows:

    Authority: 15 U.S.C. 2604, 2607, and 2625(c).

    2. By adding new Sec. 721.305 to subpart E to read as follows:


Sec. 721.305   Di-substituted acetophenone (generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as di-
substituted acetophenone (PMN P-97-93) is subject to reporting under 
this section for the significant new uses described in paragraph (a)(2) 
of this section.
    (2) The significant new uses are:
    (i) Protection in the workplace. Requirements as specified in 
Sec. 721.63 (a)(1), (a)(2)(i), (a)(2)(ii), (a)(2)(iii), (a)(3), (b) 
(concentration set at 1.0 percent), and (c).
    (ii) Hazard communication program. Requirements as specified in 
Sec. 721.72 (a), (b), (c), (d), (e) (concentration set at 1.0 percent), 
(f), (g)(2)(i), (g)(2)(v). The following statement shall appear on each 
label as specified in Sec. 721.72(b) and the MSDS as specified in 
Sec. 721.72(c): This substance is expected to be dermally absorbed and 
may cause effects to the liver, kidney, adrenal glands, and the heart.
    (iii) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec. 721.80(q).
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in 
Sec. 721.125 (a), (b), (c), (d), (e), (f), (g), (h), and (i) are 
applicable to manufacturers, importers, and processors of this 
substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec. 721.185 apply to this section.
    (3) Determining whether a specific use is subject to this section. 
The provisions of Sec. 721.1725(b)(1) apply to this section.
    3. By adding new Sec. 721.435 to subpart E to read as follows:


Sec. 721.435   Alkylphenylpolyetheralkanolamines (generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substances identified generically as 
alkylphenylpolyetheralkanolamines (PMNs P-97-880/881/882) are subject 
to reporting under this section for the significant new uses described 
in paragraph (a)(2) of this section.
    (2) The significant new uses are:
    (i) Release to water. Requirements as specified in Sec. 721.90 
(a)(1), (b)(1), and (c)(1).
    (ii) [Reserved]
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in 
Sec. 721.125 (a), (b), (c), and (k) are applicable to manufacturers, 
importers, and processors of these substances.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec. 721.185 apply to this section.
    4. By adding new Sec. 721.450 to subpart E to read as follows:


Sec. 721.450   Hydrofluorochloroalkene (generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as a 
hydrofluorochloroalkene (PMN P-97-593) is subject to reporting under 
this section for the significant new uses

[[Page 44575]]

described in paragraph (a)(2) of this section.
    (2) The significant new uses are:
    (i) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec. 721.80(g).
    (ii) [Reserved]
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. The recordkeeping requirements specified in 
Sec. 721.125 (a), (b), (c) and (i) are applicable to manufacturers, 
importers, and processors of this substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec. 721.185 apply to this section.
    5. By adding new Sec. 721.558 to subpart E to read as follows:


Sec. 721.558   Salt of a fatty alkylamine derivative (generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as a salt 
of a fatty alkylamine derivative (PMN P-96-1426) is subject to 
reporting under this section for the significant new uses described in 
paragraph (a)(2) of this section.
    (2) The significant new uses are:
    (i) Release to water. Requirements as specified in Sec. 721.90 
(a)(1), (b)(1), and (c)(1).
    (ii) [Reserved]
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in 
Sec. 721.125 (a), (b), (c), and (k) are applicable to manufacturers, 
importers, and processors of this substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec. 721.185 apply to this section.
    6. By adding new Sec. 721.630 to subpart E to read as follows:


Sec. 721.630   Salt of a modified tallow alkylenediamine (generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as a salt 
of a modified tallow alkylenediamine (PMN P-96-1425) is subject to 
reporting under this section for the significant new uses described in 
paragraph (a)(2) of this section.
    (2) The significant new uses are:
    (i) Release to water. Requirements as specified in Sec. 721.90 
(a)(1), (b)(1), and (c)(1).
    (ii) [Reserved]
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in 
Sec. 721.125 (a), (b), (c), and (k) are applicable to manufacturers, 
importers, and processors of this substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec. 721.185 apply to this section.
    7. By adding new Sec. 721.987 to subpart E to read as follows:


Sec. 721.987   Dialkylaminophenyl imino pyrazole acid ester (generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as 
dialkylaminophenyl imino pyrazole acid ester (PMN P-98-45) is subject 
to reporting under this section for the significant new uses described 
in paragraph (a)(2) of this section.
    (2) The significant new uses are:
    (i) Release to water. Requirements as specified in Sec. 721.90 
(a)(1), (b)(1), and (c)(1).
    (ii) [Reserved]
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in 
Sec. 721.125 (a), (b), (c), and (k) are applicable to manufacturers, 
importers, and processors of this substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec. 721.185 apply to this section.
    8. By adding new Sec. 721.988 to subpart E to read as follows:


Sec. 721.988   Pyrazolone azomethine dye (generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as a 
pyrazolone azomethine dye (PMN P-98-91) is subject to reporting under 
this section for the significant new uses described in paragraph (a)(2) 
of this section.
    (2) The significant new uses are:
    (i) Release to water. Requirements as specified in Sec. 721.90 
(a)(1), (b)(1), and (c)(1).
    (ii) [Reserved]
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in 
Sec. 721.125 (a), (b), (c), and (k) are applicable to manufacturers, 
importers, and processors of this substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec. 721.185 apply to this section.
    9. By adding new Sec. 721.1580 to subpart E to read as follows:


Sec. 721.1580   Disubstituted benzene ether, polymer with substituted 
phenol (generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance generically identified as 
disubstituted benzene ether, polymer with substituted phenol (PMN P-98-
155) is subject to reporting under this section for the significant new 
uses described in paragraph (a)(2) of this section.
    (2) The significant new uses are:
    (i) Release to water. Requirements as specified in Sec. 721.90 
(a)(1), (b)(1), and (c)(1).
    (ii) [Reserved]
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in 
Sec. 721.125 (a), (b), (c), and (k) are applicable to manufacturers, 
importers, and processors of this substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec. 721.185 apply to this section.
    10. By adding new Sec. 721.1710 to subpart E to read as follows:


Sec. 721.1710   Methoxy benzoic acid derivative (generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as a 
methoxy benzoic acid derivative (PMN P-98-24) is subject to reporting 
under this section for the significant new uses described in paragraph 
(a)(2) of this section.
    (2) The significant new uses are:
    (i) Release to water. Requirements as specified in Sec. 721.90 
(a)(4), (b)(4), and (c)(4) (N = 40).
    (ii) [Reserved]
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in 
Sec. 721.125 (a), (b), (c), and (k) are applicable to manufacturers, 
importers, and processors of this substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec. 721.185 apply to this section.

[[Page 44576]]

    11. By adding new Sec. 721.1734 to subpart E to read as follows:


Sec. 721.1734   Substituted benzonitrile (generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as a 
substituted benzonitrile (PMN P-97-1029) is subject to reporting under 
this section for the significant new uses described in paragraph (a)(2) 
of this section.
    (2) The significant new uses are:
    (i) Protection in the workplace. Requirements as specified in 
Sec. 721.63 (a)(2)(i), (a)(3), (a)(4), (a)(5)(ii), (a)(5)(iv), 
(a)(5)(v), and (a)(6)(v).
    (ii) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec. 721.80(g).
    (iii) Release to water. Requirements as specified in Sec. 721.90 
(a)(1), (b)(1), and (c)(1).
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. The recordkeeping requirements specified in 
Sec. 721.125 (a), (b), (c), (d), (e), (i), and (k) are applicable to 
manufacturers, importers, and processors of this substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec. 721.185 apply to this section.
    12. By adding new Sec. 721.2078 to subpart E to read as follows:


Sec. 721.2078   1-Piperidinecarboxylic acid, 2-[(dichloro-hydroxy-
carbomonocycle)hydrazono]-, methyl ester (generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance generically identified as 1-
piperidinecarboxylic acid, 2-[(dichloro-hydroxy-carbomonocycle) 
hydrazono]-, methyl ester (PMN P-96-756) is subject to reporting under 
this section for the significant new uses described in paragraph (a)(2) 
of this section.
    (2) The significant new uses are:
    (i) Protection in the workplace. Requirements as specified in 
Sec. 721.63 (a)(4), (a)(5)(i), (a)(6)(i), (a)(6)(ii), (a)(6)(iv), (b) 
(concentration set at 0.1 percent), and (c).
    (ii) Hazard communication program. Requirements as specified in 
Sec. 721.72 (a), (b), (c), (d), (e) (concentration set at 0.1 percent), 
(f), (g)(1)(iv), (g)(1)(vii), (g)(2)(ii), (g)(2)(iii), (g)(2)(iv), and 
(g)(5).
    (iii) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec. 721.80 (g), (l), and (q).
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in 
Sec. 721.125 (a), (b), (c), (d), (f), (g), (h), and (i) are applicable 
to manufacturers, importers, and processors of this substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec. 721.185 apply to this section.
    (3) Determining whether a specific use is subject to this section. 
The provisions of Sec. 721.1725(b)(1) apply to this section.
    13. By adding new Sec. 721.2079 to subpart E to read as follows:


Sec. 721.2079   Dichloro, hydroxy, hydrazino-carbomonocycle (generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance generically identified as 
dichloro, hydroxy, hydrazino-carbomonocycle (PMN P-96-757) is subject 
to reporting under this section for the significant new uses described 
in paragraph (a)(2) of this section.
    (2) The significant new uses are:
    (i) Protection in the workplace. Requirements as specified in 
Sec. 721.63 (a)(4), (a)(5)(i), (a)(6)(i), (a)(6)(ii), (a)(6)(iv), (b) 
(concentration set at 0.1 percent), and (c).
    (ii) Hazard communication program. Requirements as specified in 
Sec. 721.72 (a), (b), (c), (d), (e) (concentration set at 0.1 percent), 
(f), (g)(1)(iv), (g)(1)(vii), (g)(2)(ii), (g)(2)(iii), (g)(2)(iv), and 
(g)(5).
    (iii) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec. 721.80 (g), (l), and (q).
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in 
Sec. 721.125 (a), (b), (c), (d), (f), (g), (h), and (i) are applicable 
to manufacturers, importers, and processors of this substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec. 721.185 apply to this section.
    (3) Determining whether a specific use is subject to this section. 
The provisions of Sec. 721.1725(b)(1) apply to this section.
    14. By adding new Sec. 721.2081 to subpart E to read as follows:


Sec. 721.2081   Dichloro, hydroxy, hydrazino-carbomonocycle-
monohydrochloride (generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance generically identified as 
dichloro, hydroxy, hydrazino-carbomonocycle-monohydrochloride (PMN P-
96-758) is subject to reporting under this section for the significant 
new uses described in paragraph (a)(2) of this section.
    (2) The significant new uses are:
    (i) Protection in the workplace. Requirements as specified in 
Sec. 721.63 (a)(4), (a)(5)(i), (a)(6)(i), (a)(6)(ii), (a)(6)(iv), (b) 
(concentration set at 0.1 percent), and (c).
    (ii) Hazard communication program. Requirements as specified in 
Sec. 721.72 (a), (b), (c), (d), (e) (concentration set at 0.1 percent), 
(f), (g)(1)(iv), (g)(1)(vii), (g)(2)(ii), (g)(2)(iii), (g)(2)(iv), and 
(g)(5).
    (iii) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec. 721.80 (g), (l), and (q).
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in 
Sec. 721.125 (a), (b), (c), (d), (f), (g), (h), and (i) are applicable 
to manufacturers, importers, and processors of this substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec. 721.185 apply to this section.
    (3) Determining whether a specific use is subject to this section. 
The provisions of Sec. 721.1725(b)(1) apply to this section.
    15. By adding new Sec. 721.2083 to subpart E to read as follows:


Sec. 721.2083   Polysubstituted carbomonocyclic hydroxylamine 
(generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as a 
polysubstituted carbomonocyclic hydroxylamine (PMN P-97-878) is subject 
to reporting under this section for the significant new uses described 
in paragraph (a)(2) of this section.
    (2) The significant new uses are:
    (i) Protection in the workplace. Requirements as specified in 
Sec. 721.63 (a)(4), (a)(5)(ii), (a)(5)(iv), (a)(5)(v), and (a)(6)(1).
    (ii) [Reserved]
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. The recordkeeping requirements specified in 
Sec. 721.125 (a), (b), (c), and (d) are applicable to manufacturers, 
importers, and processors of this substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec. 721.185 apply to this section.
    16. By adding new Sec. 721.2480 to subpart E to read as follows:

[[Page 44577]]

Sec. 721.2480   Isoalkyldimethylamine (generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as 
isoalkyldimethylamine (PMN P-96-1320) is subject to reporting under 
this section for the significant new uses described in paragraph (a)(2) 
of this section.
    (2) The significant new uses are:
    (i) Release to water. Requirements as specified in Sec. 721.90 
(a)(4), (b)(4), and (c)(4) (N = 3).
    (ii) [Reserved]
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in 
Sec. 721.125 (a), (b), (c), and (k) are applicable to manufacturers, 
importers, and processors of this substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec. 721.185 apply to this section.
    17. By adding new Sec. 721.2485 to subpart E to read as follows:


Sec. 721.2485   1,3-Dioxolane, 2-ethenyl-.

    (a) Chemical substances and significant new uses subject to 
reporting. (1) The chemical substance identified as 1,3-Dioxolane, 2-
ethenyl- (PMN P-96-1006; CAS No. 3984-22-3) is subject to reporting 
under this section for the significant new uses described in paragraph 
(a)(2) of this section.
    (2) The significant new uses are:
    (i) Protection in the workplace. Requirements as specified in 
Sec. 721.63 (a)(1), (a)(2)(i), (a)(2)(ii), (a)(3)(i), (a)(4), 
(a)(5)(iii), (a)(5)(xii), (a)(5)(xiii), (a)(5)(xiv), (a)(6)(v), (b) 
(concentration set at 1.0 percent), and (c). The imperviousness of each 
item pursuant to (a)(2)(i) and (a)(2)(ii) must be demonstrated by 
actual testing under (a)(3)(i) and not by manufacturer specifications. 
Permeation testing shall be conducted according to the ASTM F739 
``Standard Test Method for Resistance of Protective Clothing Materials 
to Permeation by Liquids or Gases.'' Results shall be recorded as a 
cumulative permeation rate as a function of time, and shall be 
documented in accordance with ASTM F739 using the format specified in 
ASTM F1194-89 ``Guide for Documenting the Results of Chemical 
Permeation Testing on Protective Clothing Materials.'' Gloves may not 
be used for a time period longer than they are actually tested and must 
be replaced at the end of each work shift. The manufacturer, importer, 
or processor must submit all test data to the Agency and must receive 
written Agency approval for each type of glove tested prior to use of 
such gloves.
    (ii) Hazard communication program. Requirements as specified in 
Sec. 721.72 (a), (b), (c), (d), (e) (concentration set at 1.0 percent), 
(f), (g)(1)(iii), (g)(1)(iv), (g)(2)(ii), (g)(2)(iii), and (g)(5). The 
following statements shall appear on each label as specified in 
Sec. 721.72(b) and the MSDS as specified in Sec. 721.72(c): This 
substance may cause fatality. When using this substance avoid dermal 
contact. When using this substance use respiratory protection or 
engineering and process controls to mitigate respiratory exposure. When 
using this substance use dermal protection to prevent dermal exposure.
    (iii) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec. 721.80(j).
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in 
Sec. 721.125 (a), (b), (c), (d), (e), (f), (g), and (h) are applicable 
to manufacturers, importers, and processors of this substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec. 721.185 apply to this section.
    18. By adding new Sec. 721.2532 to subpart E to read as follows:


Sec. 721.2532   Substituted diphenylmethane (generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as a 
substituted diphenylmethane (PMN P-97-4) is subject to reporting under 
this section for the significant new uses described in paragraph (a)(2) 
of this section.
    (2) The significant new uses are:
    (i) Release to water. Requirements as specified in Sec. 721.90 
(a)(1), (b)(1), and (c)(1).
    (ii) [Reserved]
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in 
Sec. 721.125 (a), (b), (c), and (k) are applicable to manufacturers, 
importers, and processors of this substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec. 721.185 apply to this section.
    19. By adding new Sec. 721.2570 to subpart E to read as follows:


Sec. 721.2570   Alkylated diphenyls (generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substances identified generically as 
alkylated diphenyls (PMNs P-97-869/870/871) are subject to reporting 
under this section for the significant new uses described in paragraph 
(a)(2) of this section.
    (2) The significant new uses are:
    (i) Release to water. Requirements as specified in Sec. 721.90 
(a)(4), (b)(4), and (c)(4) (N = 1).
    (ii) [Reserved]
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in 
Sec. 721.125 (a), (b), (c), and (k) are applicable to manufacturers, 
importers, and processors of these substances.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec. 721.185 apply to this section.
    20. By adding new Sec. 721.2580 to subpart E to read as follows:


Sec. 721.2580   C.I. Disperse Red 152 (generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as C.I. 
disperse red 152 (PMN P-97-820) is subject to reporting under this 
section for the significant new uses described in paragraph (a)(2) of 
this section.
    (2) The significant new uses are:
    (i) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec. 721.80 (v)(1), (w)(1), and (x)(1).
    (ii) [Reserved]
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements specified in 
Sec. 721.125 (a), (b), (c), and (i) are applicable to manufacturers, 
importers, and processors of this substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec. 721.185 apply to this section.
    21. By adding new Sec. 721.2585 to subpart E to read as follows:


Sec. 721.2585   Sodium salts of dodecylphenol (generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substances identified generically as sodium 
salts of dodecylphenol (PMNs P-97-1060/1061/1062) are subject to 
reporting under this

[[Page 44578]]

section for the significant new uses described in paragraph (a)(2) of 
this section.
    (2) The significant new uses are:
    (i) Release to water. Requirements as specified in Sec. 721.90 
(a)(4), (b)(4), and (c)(4) (N = 1).
    (ii) [Reserved]
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in 
Sec. 721.125 (a), (b), (c), and (k) are applicable to manufacturers, 
importers, and processors of these substances.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec. 721.185 apply to this section.
    22. By adding new Sec. 721.3031 to subpart E to read as follows:


Sec. 721.3031   Boric acid (H3BO3), zinc salt 
(2=3).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified as boric acid 
(H3BO3), zinc salt (2=3) (PMN P-97-552; CAS No. 
10192-46-8) is subject to reporting under this section for the 
significant new uses described in paragraph (a)(2) of this section.
    (2) The significant new uses are:
    (i) Release to water. Requirements as specified in Sec. 721.90 
(a)(4), (b)(4), and (c)(4) (N = 3).
    (ii) [Reserved]
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in 
Sec. 721.125 (a), (b), (c), and (k) are applicable to manufacturers, 
importers, and processors of this substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec. 721.185 apply to this section.
    23. By adding new Sec. 721.3032 to subpart E to read as follows:


Sec. 721.3032   Boric acid (H3BO2), zinc salt.

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified as boric acid 
(H3BO2), zinc salt (PMN P-97-553; CAS No. 14720-
55-9) are subject to reporting under this section for the significant 
new uses described in paragraph (a)(2) of this section.
    (2) The significant new uses are:
    (i) Release to water. Requirements as specified in Sec. 721.90 
(a)(4), (b)(4), and (c)(4) (N = 3).
    (ii) [Reserved]
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in 
Sec. 721.125 (a), (b), (c), and (k) are applicable to manufacturers, 
importers, and processors of this substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec. 721.185 apply to this section.
    24. By adding new Sec. 721.3635 to subpart E to read as follows:


Sec. 721.3635   Octadecanoic acid, ester with 1,2-propanediol, 
phosphate, anhydride with silicic acid (H4SiO4).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified as octadecanoic acid, 
ester with 1,2-propanediol, phosphate, anhydride with silicic acid 
(H4SiO4) (PMN P-96-1520; CAS No. 177771-31-2) is 
subject to reporting under this section for the significant new uses 
described in paragraph (a)(2) of this section.
    (2) The significant new uses are:
    (i) Hazard communication program. Requirements as specified in 
Sec. 721.72 (a), (b), (c), (d), (f), (g)(3)(ii), (g)(4)(i), and (g)(5). 
The following statement shall appear on each label as specified in 
Sec. 721.72(b) and the MSDS as specified in Sec. 721.72(c): Do not 
release into the environment in quantities that allow surface water 
concentrations to exceed 6 ppb.
    (ii) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec. 721.80(p) (15 months).
    (iii) Release to water. Requirements as specified in Sec. 721.90 
(a)(4), (b)(4), and (c)(4) (N = 6).
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in 
Sec. 721.125 (a), (b), (c), (f), (g), (h), (i), and (k) are applicable 
to manufacturers, importers, and processors of this substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec. 721.185 apply to this section.
    25. By adding new Sec. 721.4097 to subpart E to read as follows:


Sec. 721.4097   7-Oxabicyclo[4.1.0]heptane-3-carboxylic acid, methyl 
ester.

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified as 7-
oxabicyclo[4.1.0]heptane-3-carboxylic acid, methyl ester (PMN P-98-101) 
is subject to reporting under this section for the significant new uses 
described in paragraph (a)(2) of this section.
    (2) The significant new uses are:
    (i) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec. 721.80(g).
    (ii) [Reserved]
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. The recordkeeping requirements specified in 
Sec. 721.125 (a), (b), (c) and (i) are applicable to manufacturers, 
importers, and processors of this substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec. 721.185 apply to this section.
    26. By adding new Sec. 721.4098 to subpart E to read as follows:


Sec.  721.4098   Substituted heteroaromatic-2[[4-(dimethylamino) 
phenyl]azo]-3-methyl-, salts (generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substances identified generically as 
substituted heteroaromatic-2[[4-(dimethylamino)phenyl]azo]-3-methyl-, 
salts (PMNs P-97-582 and P-97-583) are subject to reporting under this 
section for the significant new uses described in paragraph (a)(2) of 
this section.
    (2) The significant new uses are:
    (i) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec. 721.80(f).
    (ii) [Reserved]
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in 
Sec. 721.125 (a), (b), (c), and (i) are applicable to manufacturers, 
importers, and processors of this substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec. 721.185 apply to this section.
    27. By adding new Sec.  721.5290 to subpart E to read as follows:


Sec. 721.5290   Phenylazoalkoxy naphthylamines (generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substances identified generically as 
phenylazoalkoxy napthylamines (PMNs P-97-42 and P-97-43) are subject to 
reporting under this section for the significant new uses described in 
paragraph (a)(2) of this section.

[[Page 44579]]

    (2) The significant new uses are:
    (i) Release to water. Requirements as specified in Sec. 721.90 
(a)(4), (b)(4), and (c)(4) (N = 50 for P-97-42) (N = 40 for P-97-43).
    (ii) [Reserved]
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in 
Sec. 721.125 (a), (b), (c), and (k) are applicable to manufacturers, 
importers, and processors of these substances.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec. 721.185 apply to this section.
    28. By adding new Sec. 721.5356 to subpart E to read as follows:


Sec. 721.5356   Ethanol, 2,2'2''-nitrilotris-, compound with alpha-
2,4,6-tris (1-phenylethyl)phenyl]-omega-hydroxypoly (oxy-1,2-
ethanediyl) phosphate.

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified as ethanol, 2,2'2''-
nitrilotris-, compound with alpha-[2,4,6-tris(1-phenylethyl)phenyl]-
omega-hydroxypoly (oxy-1,2-ethanediyl) phosphate (PMN P-98-185) is 
subject to reporting under this section for the significant new uses 
described in paragraph (a)(2) of this section.
    (2) The significant new uses are:
    (i) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec. 721.80 (f) and (j) (pesticide inert).
    (ii) [Reserved]
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. The recordkeeping requirements specified in 
Sec. 721.125 (a), (b), (c), and (i) are applicable to manufacturers, 
importers, and processors of this substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec. 721.185 apply to this section.
    29. By adding new Sec. 721.5360 to subpart E to read as follows:


Sec. 721.5360   Substituted nitrobenezene (generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as 
substituted nitrobenezene (PMN P-97-1028) is subject to reporting under 
this section for the significant new uses described in paragraph (a)(2) 
of this section.
    (2) The significant new uses are:
    (i) Protection in the workplace. Requirements as specified in 
Sec. 721.63 (a)(2)(i), (a)(3), (a)(4), (a)(5)(ii), (a)(5)(iv), 
(a)(5)(v), and (a)(6)(v).
    (ii) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec. 721.80(g).
    (iii) Release to water. Requirements as specified in Sec. 721.90 
(a)(1), (b)(1), and (c)(1).
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. The recordkeeping requirements specified in 
Sec. 721.125 (a), (b), (c), (d), (e), (i), and (k) are applicable to 
manufacturers, importers, and processors of this substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec. 721.185 apply to this section.
    30. By adding new Sec. 721.5548 to subpart E to read as follows:


Sec. 721.5548   Mixed metal oxide (generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as a mixed 
metal oxide (PMN P-97-956) is subject to reporting under this section 
for the significant new uses described in paragraph (a)(2) of this 
section.
    (2) The significant new uses are:
    (i) Protection in the workplace. Requirements as specified in 
Sec. 721.63 (a)(4), (a)(5)(iii), (a)(5)(iv), and (a)(6)(i).
    (ii) [Reserved]
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. The recordkeeping requirements specified in 
Sec. 721.125 (a), (b), (c), and (d) are applicable to manufacturers, 
importers, and processors of this substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec. 721.185 apply to this section.
    31. By adding new Sec. 721.5580 to subpart E to read as follows:


Sec. 721.5580   Oxirane, 2,2'-[methylenebis[(2,6-dimethyl-4,1-
phenylene)oxymethylene]]bis-.

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified as oxirane, 2,2'-
[methylenebis[(2,6-dimethyl-4,1-phenylene)oxymethylene]]bis- (PMN P-97-
1011; CAS No. 93705-66-9) is subject to reporting under this section 
for the significant new uses described in paragraph (a)(2) of this 
section.
    (2) The significant new uses are:
    (i) Protection in the workplace. Requirements as specified in 
Sec. 721.63 (a)(4), (a)(5)(iii), (a)(5)(iv), (a)(5)(v), (a)(5)(vi), 
(a)(5)(vii), (a)(6)(i), (a)(6)(ii), (a)(6)(iv), (b) (concentration set 
at 0.1 percent), and (c). As an alternative to the respiratory 
requirements listed here, a manufacturer, importer, or processor may 
choose to follow the new chemical exposure limit (NCEL) provisions 
listed in the TSCA section 5(e) consent order for this substance. The 
NCEL is 0.35 milligram/meter3 (mg/m3).
    (ii) Hazard communication program. Requirements as specified in 
Sec. 721.72 (a), (b), (c), (d), (e) (concentration set 0.1 percent), 
(f), (g)(1)(vi), (g)(1)(vii), (g)(2)(ii), (g)(2)(iv), (g)(3)(i), 
(g)(3)(ii), (g)(4)(i), (g)(4)(iii), and (g)(5).
    (iii) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec. 721.80 (f) and (q).
    (iv) Release to water. Requirements as specified in Sec. 721.90 
(a)(1), (b)(1), and (c)(1).
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in 
Sec. 721.125 (a), (b), (c), (d), (f), (g), (h), (i), and (k) are 
applicable to manufacturers, importers, and processors of this 
substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec. 721.185 apply to this section.
    (3) Determining whether a specific use is subject to this section. 
The provisions of Sec. 721.1725(b)(1) apply to this section.
    32. By adding new Sec. 721.5775 to subpart E to read as follows:


Sec. 721.5775   Phenol, 5-amino-2,4-dicholoro-, hydrochloride.

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified as phenol, 5-amino-
2,4-dicholoro-, hydrochloride (PMN P-98-198) is subject to reporting 
under this section for the significant new uses described in paragraph 
(a)(2) of this section.
    (2) The significant new uses are:
    (i) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec. 721.80 (v)(i), (w)(i), and (x)(i).
    (ii) Release to water. Requirements as specified in Sec. 721.90 
(a)(1), (b)(1), and (c)(1).
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in 
Sec. 721.125

[[Page 44580]]

(a), (b), (c), (i), and (k) are applicable to manufacturers, importers, 
and processors of this substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec. 721.185 apply to this section.
    33. By adding new Sec. 721.5965 to subpart E to read as follows:


Sec. 721.5965   Substituted S-phenylthiazole (generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as 
substituted s-phenylthiazole (PMN P-97-1046) is subject to reporting 
under this section for the significant new uses described in paragraph 
(a)(2) of this section.
    (2) The significant new uses are:
    (i) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec. 721.80(f).
    (ii) [Reserved]
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in 
Sec. 721.125 (a), (b), (c), and (i) are applicable to manufacturers, 
importers, and processors of this substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec. 721.185 apply to this section.
    34. By adding new Sec. 721.6175 to subpart E to read as follows:


Sec. 721.6175   2-Piperdinone, 1,3-dimethyl-.

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified as 2-Piperdinone, 1,3-
dimethyl- (PMN P-97-520; CAS No. 1690-76-2) is subject to reporting 
under this section for the significant new uses described in paragraph 
(a)(2) of this section.
    (2) The significant new uses are:
    (i) Protection in the workplace. Requirements as specified in 
Sec. 721.80(j).
    (ii) [Reserved]
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. The recordkeeping requirements specified in 
Sec. 721.125 (a), (b), (c), and (i) are applicable to manufacturers, 
importers, and processors of this substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec. 721.185 apply to this section.
    35. By adding new Sec. 721.6176 to subpart E to read as follows:


Sec. 721.6176   2-Piperdinone, 1,5-dimethyl-.

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substances identified as 2-Piperdinone, 
1,5-dimethyl- (PMN P-97-521; CAS No. 86917-58-0) is subject to 
reporting under this section for the significant new uses described in 
paragraph (a)(2) of this section.
    (2) The significant new uses are:
    (i) Protection in the workplace. Requirements as specified in 
Sec. 721.80(j).
    (ii) [Reserved]
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. The recordkeeping requirements specified in 
Sec. 721.125 (a), (b), (c), and (i) are applicable to manufacturers, 
importers, and processors of this substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec. 721.185 apply to this section.
    36. By adding new Sec. 721.6498 to subpart E to read as follows:


Sec. 721.6498   Modified polyisocyanates (generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as 
modified polyisocyanates (PMN P-96-1428) is subject to reporting under 
this section for the significant new uses described in paragraph (a)(2) 
of this section.
    (2) The significant new uses are:
    (i) Protection in the workplace. Requirements as specified in 
Sec. 721.63 (a)(1), (a)(3), (a)(4), (a)(5)(ii), (a)(5)(viii), 
(a)(5)(ix), (a)(6)(ii), (b) (concentration set at 0.1 percent), and 
(c). As an alternative to the respiratory requirements listed here, a 
manufacturer, importer, or processor may choose to follow the NCEL 
provisions listed in the TSCA section 5(e) consent order for this 
substance. The NCEL is 0.05 mg/m3.
    (ii) Hazard communication program. Requirements as specified in 
Sec. 721.72 (a), (b), (c), (d), (e) (concentration set at 0.1 percent), 
(f), and (g)(5). The following statements shall appear on each label as 
specified in Sec. 721.72(b) and the MSDS as specified in 
Sec. 721.72(c): Warnings. Exposure to diisocyanates may cause the 
following human health effects: Skin irritation and allergic reactions, 
respiratory irritation, respiratory sensitization, and lung toxicity; 
some diisocyanates also may cause cancer. The likelihood that these 
effects will occur depends on a number of factors; among them, the 
level of exposure, frequency of exposure, part of the body exposed, and 
sensitivity of the exposed individual. Symptoms of allergic reaction 
and respiratory sensitization include rashes, cough, shortness of 
breath, asthma, chest tightness and other breathing difficulties. There 
is uncertainty as to the mechanism by which sensitization occurs. In 
sensitized individuals, exposure to even small amounts of diisocyanates 
(below government-recommended workplace exposure levels) may cause 
allergic respiratory reactions like asthma and severe breathing 
difficulties. It is especially important to note that contact with skin 
may lead to respiratory sensitization or cause other allergic 
reactions. In some cases, the effects of diisocyanate exposure may be 
immediate and life-threatening; in others, the effects may be delayed 
and occur hours after the exposure has ended. Repeated or prolonged 
exposure to diisocyanates may also cause irritation to eyes, skin, 
respiratory tract and lungs, as well as adverse chronic lung effects, 
like decreased lung capacity and function. Individuals experiencing 
shortness of breath, tightness in the chest or other problems breathing 
should seek immediate medical attention. When using this substance the 
following protective measures should be used: In workplaces where 
individuals handle diisocyanates or coatings or other formulations that 
contain them, an industrial hygiene and safety program should be 
operative. Important components of this program include: Hazard 
communication and training on safe handling practices; use of efficient 
and well-maintained application equipment, engineering controls and 
personal protective equipment; housekeeping procedures including spill 
prevention and cleanup practices; and, if feasible, means to measure 
airborne levels of polyisocyanates and diisocyanates. During spray 
applications, workers should take precautions to avoid breathing 
vapors, mists or aerosols. Inhalation exposures should be limited to < 
0.05 mg/m3 as an 8-hour time-weighted average (TWA) for 
combined polyisocyanates and diisocyanates. Engineering controls should 
serve as the first, most effective means of reducing airborne 
polyisocyanate and diisocyanate concentrations; an appropriate National 
Institute for Occupational Safety and Health/Mine Safety and Health 
Administration (NIOSH/MSHA) approved respirator should be used as a 
secondary tool to lower exposures. Currently, downdraft spray booths 
and high-volume low-pressure (HVLP) spray guns appear to offer the most 
efficient

[[Page 44581]]

technology to reduce inhalation exposures; a maintenance program should 
always be used to ensure optimal operating efficiencies. To limit 
dermal contact, individuals should wear impermeable gloves, protective 
clothing and goggles or glasses with side shields.
    (iii) Industrial, commercial, and consumer activites. Requirements 
as specified in Sec. 721.80(q).
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in 
Sec. 721.125 (a), (b), (c), (d), (e), (f), (g), (h), and (i) are 
applicable to manufacturers, importers, and processors of this 
substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec. 721.185 apply to this section.
    (3) Determining whether a specific use is subject to this section. 
The provisions of Sec. 721.1725(b)(1) apply to this section.
    37. By adding new Sec. 721.7285 to subpart E to read as follows:


Sec. 721.7285   Amines, N-cocoalkyltrimethylenedi-, citrates.

    (a) Chemical substances and significant new uses subject to 
reporting. (1) The chemical substance identified as amines, N-
cocoalkyltrimethylenedi-, citrates. (PMN P-93-880; CAS No. 189120-63-6) 
is subject to reporting under this section for the significant new uses 
described in paragraph (a)(2) of this section.
    (2) The significant new uses are:
    (i) Hazard communication program. Requirements as specified in 
Sec. 721.72 (a), (b), (c), (d), (f), (g)(3)(ii), (g)(4)(iii), and 
(g)(5).
    (ii) Release to water. Requirements as specified in Sec. 721.90 
(a)(1), (b)(1), and (c)(1).
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in 
Sec. 721.125 (a), (b), (c), (f), (g), (h), and (k) are applicable to 
manufacturers, importers, and processors of this substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec. 721.185 apply to this section.
    38. By adding new Sec. 721.7286 to subpart E to read as follows:


Sec. 721.7286   Amines, N-tallowalkyltripropylenetetra-, citrates.

    (a) Chemical substances and significant new uses subject to 
reporting. (1) The chemical substance identified as amines, N-
tallowalkyltripropylenetetra-, citrates (PMN P-93-881; CAS No. 189120-
62-5) is subject to reporting under this section for the significant 
new uses described in paragraph (a)(2) of this section.
    (2) The significant new uses are:
    (i) Hazard communication program. Requirements as specified in 
Sec. 721.72 (a), (b), (c), (d), (f), (g)(3)(ii), (g)(4)(iii), and 
(g)(5).
    (ii) Release to water. Requirements as specified in Sec. 721.90 
(a)(1), (b)(1), and (c)(1).
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in 
Sec. 721.125 (a), (b), (c), (f), (g), (h), and (k) are applicable to 
manufacturers, importers, and processors of this substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec. 721.185 apply to this section.
    39. By adding new Sec. 721.7785 to subpart E to read as follows:


Sec. 721.7785   Substituted alkyl aminomethylene polyphosphonic acid, 
salt (generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as a 
substituted alkylamino methylene polyphosphonic acid, salt (PMN P-97-
1095) is subject to reporting under this section for the significant 
new uses described in paragraph (a)(2) of this section.
    (2) The significant new uses are:
    (i) Release to water. Requirements as specified in Sec. 721.90 
(a)(1), (b)(1), and (c)(1).
    (ii) [Reserved]
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in 
Sec. 721.125 (a), (b), (c), and (k) are applicable to manufacturers, 
importers, and processors of this substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec. 721.185 apply to this section.
    40. By adding new Sec. 721.8153 to subpart E to read as follows:


Sec. 721.8153   Di-substituted propanedione (generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as di-
substituted propanedione (PMN P-97-94) is subject to reporting under 
this section for the significant new uses described in paragraph (a)(2) 
of this section.
    (2) The significant new uses are:
    (i) Protection in the workplace. Requirements as specified in 
Sec. 721.63 (a)(1), (a)(2)(i), (a)(2)(ii), (a)(2)(iii), (a)(3), (b) 
(concentration set at 1.0 percent), and (c).
    (ii) Hazard communication program. Requirements as specified in 
Sec. 721.72 (a), (b), (c), (d), (e) (concentration set at 1.0 percent), 
(f), (g)(2)(i), (g)(2)(v). The following statement shall appear on each 
label as specified in Sec. 721.72(b) and the MSDS as specified in 
Sec. 721.72(c): This substance is expected to be dermally absorbed and 
may cause effects to the liver, kidney, adrenal glands, and the heart.
    (iii) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec. 721.80(q).
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in 
Sec. 721.125 (a), (b), (c), (d), (e), (f), (g), (h), and (i) are 
applicable to manufacturers, importers, and processors of this 
substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec. 721.185 apply to this section.
    (3) Determining whether a specific use is subject to this section. 
The provisions of Sec. 721.1725(b)(1) apply to this section.
    41. By adding new Sec. 721.8660 to subpart E to read as follows:


Sec. 721.8660   Propionic acid methyl ester (generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as a 
propionic acid methyl ester (PMN P-97-370) is subject to reporting 
under this section for the significant new uses described in paragraph 
(a)(2) of this section.
    (2) The significant new uses are:
    (i) Protection in the workplace. Requirements as specified in 
Sec. 721.63 (a)(1), (a)(2)(i), and (a)(3).
    (ii) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec. 721.80 (f) and (j).
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. The recordkeeping requirements specified in 
Sec. 721.125 (a), (b), (c), (d), (e), and (i) are applicable to

[[Page 44582]]

manufacturers, importers, and processors of this substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec. 721.185 apply to this section.
    42. By adding new Sec. 721.9490 to subpart E to read as follows:


Sec. 721.9490   Coco alklydimethyl amine salts (generic).

    (a) Chemical substances and significant new uses subject to 
reporting. (1) The chemical substances identified generically as coco 
alkyldimethyl amine salts (PMNs P-98-412/414/415/416/417) are subject 
to reporting under this section for the significant new uses described 
in paragraph (a)(2) of this section.
    (2) The significant new uses are:
    (i) Release to water. Requirements as specified in Sec. 721.90 
(a)(1), (b)(1), and (c)(1).
    (ii) [Reserved]
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in 
Sec. 721.125 (a), (b), (c), and (k) are applicable to manufacturers, 
importers, and processors of this substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec. 721.185 apply to this section.
    43. By adding new Sec. 721.9516 to subpart E to read as follows:


Sec. 721.9516   Siloxanes and silicones, 3-[(2-aminoethyl) amino]propyl 
Me, di-Me, reaction products with polyethylene-polypropylene glycol Bu 
glycidal ether.

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as 
siloxanes and silicones, 3-[(2-aminoethyl) amino]propyl Me, di-Me, 
reaction products with polyethylene-polypropylene glycol Bu glycidyl 
ether (PMN P-97-740; CAS No. 189354-73-2) is subject to reporting under 
this section for the significant new uses described in paragraph (a)(2) 
of this section.
    (2) The significant new uses are:
    (i) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec. 721.80(y)(1).
    (ii) [Reserved]
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements specified in 
Sec. 721.125 (a), (b), (c), and (i) are applicable to manufacturers, 
importers, and processors of this substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec. 721.185 apply to this section.
    44. By adding new Sec. 721.9517 to subpart E to read as follows:


Sec. 721.9517   Siloxanes and silicones, de-Me, 3-[4-[[[3-(dimethyl 
amino) propyl] amino]carbonyl]-2-oxo-1-pyrrolidinyl] propyl Me.

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified as siloxanes and 
silicones, de-Me, 3-[4-[[[3-(dimethylamino) propyl]amino] carbonyl]-2-
oxo-1-pyrrolidinyl]propyl Me (PMN P-97-332) is subject to reporting 
under this section for the significant new uses described in paragraph 
(a)(2) of this section.
    (2) The significant new uses are:
    (i) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec. 721.80(y)(1).
    (ii) [Reserved]
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in 
Sec. 721.125 (a), (b), (c), and (i) are applicable to manufacturers, 
importers, and processors of this substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec. 721.185 apply to this section.
    45. By adding new Sec. 721.9595 to subpart E to read as follows:


Sec. 721.9595   Alkyl benzene sulfonic acids and alkyl sulfates, amine 
salts (generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substances identified generically as alkyl 
benzene sulfonic acids and alkyl sulfates, amine salts (PMNs P-97-296/
297/298/299) are subject to reporting under this section for the 
significant new uses described in paragraph (a)(2) of this section.
    (2) The significant new uses are:
    (i) Release to water. Requirements as specified in Sec. 721.90 
(a)(1), (b)(1), and (c)(1).
    (ii) [Reserved]
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in 
Sec. 721.125 (a), (b), (c), and (k) are applicable to manufacturers, 
importers, and processors of these substances.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec. 721.185 apply to this section.
    46. By adding new Sec. 721.9661 to subpart E to read as follows:


Sec. 721.9661   Diphenol tars (generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as 
diphenol tars (PMN P-97-813) is subject to reporting under this section 
for the significant new uses described in paragraph (a)(2) of this 
section.
    (2) The significant new uses are:
    (i) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec. 721.80(j).
    (ii) [Reserved]
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in 
Sec. 721.125 (a), (b), (c), and (k) are applicable to manufacturers, 
importers, and processors of this substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec. 721.185 apply to this section.
    47. By adding new Sec. 721.9663 to subpart E to read as follows:


Sec. 721.9663   Poly(oxy-1,2-ethanediyl), alpha, alpha'-[thiobis (1-
oxo-3,1-propanediyl)]bis [omega-hydroxy-,bis (C11-15 and 
C11-15-isoalkyl) ethers.

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified as poly(oxy-1,2-
ethanediyl), alpha, alpha'-[thiobis (1-oxo-3,1-propanediyl)]bis [omega-
hydroxy-,bis(C11-15 and C11-15-isoalkyl) ethers 
(PMN P-97-497; CAS No. 174254-18-3) is subject to reporting under this 
section for the significant new uses described in paragraph (a)(2) of 
this section.
    (2) The significant new uses are:
    (i) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec. 721.80(j).
    (ii) [Reserved]
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. The recordkeeping requirements specified in 
Sec. 721.125 (a), (b), (c), and (i) are applicable to manufacturers, 
importers, and processors of this substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec. 721.185 apply to this section.

[[Page 44583]]

    48. By adding new Sec. 721.9685 to subpart E to read as follows:


Sec. 721.9685   Mixed trialkylamines (generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substances identified generically as mixed 
trialkylamines (PMNs P-97-943/944/945/946/947/948) are subject to 
reporting under this section for the significant new uses described in 
paragraph (a)(2) of this section.
    (2) The significant new uses are:
    (i) Release to water. Requirements as specified in Sec. 721.90 
(a)(1), (b)(1), and (c)(1).
    (ii) [Reserved]
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in 
Sec. 721.125 (a), (b), (c), and (k) are applicable to manufacturers, 
importers, and processors of these substances.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec. 721.185 apply to this section.
    49. By adding new Sec. 721.9719 to subpart E to read as follows:


Sec. 721.9719   Tris carbamoyl triazine (generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as tris 
carbamoyl triazine (PMN P-95-1098) is subject to reporting under this 
section for the significant new uses described in paragraph (a)(2) of 
this section.
    (2) The significant new uses are:
    (i) Hazard communication program. Requirements as specified in 
Sec. 721.72 (a), (b), (c), (d), (f), (g)(3)(i), (g)(3)(ii), (g)(4)(i), 
and (g)(5).
    (ii) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec. 721.80(q).
    (iii) Release to water. Requirements as specified in Sec. 721.90 
(a)(4), (b)(4), and (c)(4) (N = 40).
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in 
Sec. 721.125 (a), (b), (c), (f), (g), (h), (i), and (k) are applicable 
to manufacturers, importers, and processors of this substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec. 721.185 apply to this section.
    (3) Determining whether a specific use is subject to this section. 
The provisions of Sec. 721.1725(b)(1) apply to this section.
    50. By adding new Sec. 721.9969 to subpart E to read as follows:


Sec. 721.9969   3,6-Bis(dialkylamino) -9-[2-alkoxycarbonyl) phenyl]-
xanthylium salt (generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as 3,6-
bis(dialkylamino) -9-[2-alkoxycarbonyl) phenyl]-xanthylium salt (PMN P-
97-854) is subject to reporting under this section for the significant 
new uses described in paragraph (a)(2) of this section.
    (2) The significant new uses are:
    (i) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec. 721.80 (f) and (j).
    (ii) [Reserved]
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in 
Sec. 721.125 (a), (b), (c), and (i) are applicable to manufacturers, 
importers, and processors of this substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec. 721.185 apply to this section.
    51. By adding new Sec. 721.9973 to subpart E to read as follows:


Sec. 721.9973   Zirconium dichlorides (generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substances identified generically as 
zirconium dichlorides (PMNs P-97-179/181/189/769/775/781/782/783) are 
subject to reporting under this section for the significant new uses 
described in paragraph (a)(2) of this section.
    (2) The significant new uses are:
    (i) Release to water. Requirements as specified in Sec. 721.90 
(a)(4), (b)(4), and (c)(4) (N = 20).
    (ii) [Reserved]
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in 
Sec. 721.125 (a), (b), (c), and (k) are applicable to manufacturers, 
importers, and processors of these substances.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec. 721.185 apply to this section.

[FR Doc. 98-22441 Filed 8-19-98; 8:45 am]
BILLING CODE 6560-50-F