[Federal Register Volume 62, Number 167 (Thursday, August 28, 1997)]
[Notices]
[Page 45633]
From the Federal Register Online via the Government Publishing Office [www.gpo.gov]
[FR Doc No: 97-22872]


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DEPARTMENT OF DEFENSE

Department of the Army


Availability of Non-Exclusive, Exclusive, or Partially Exclusive 
Licensing of U.S. Patent Application Concerning ``Bacterial 
Superantigen Vaccines''

AGENCY: U.S. Army Medical Research and Materiel Command, DoD.

ACTION: Notice of availability.

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SUMMARY: In accordance with 38 CFR 404.6, announcement is made of the 
availability of U.S. Patent Application SN 08/882,431 entitled 
``Bacterial Superantigen Vaccines.'' This patent has been assigned to 
the United States Government as represented by the Secretary of the 
Army.

ADDRESSES: Commander, U.S. Army Medical Research and Materiel Command, 
Command Judge Advocate, MCMR-JA, 504 Scott Street, Fort Detrick, MD 
21702-5012.

FOR FURTHER INFORMATION CONTACT:
Mr. John F. Moran, Patent Attorney, 301-619-7807, Fax 301-619-5034.

SUPPLEMENTARY INFORMATION: ``Recombinant vaccines for control of 
bacterial superantigen-associated diseases have been developed. These 
include vaccines of staphylococcal enterotoxin A, staphylococcal 
enterotoxin B, staphylococcal enterotoxin C1, toxic-shock syndrome 
toxin-1, and streptococcal pyrogenic exotoxin-A. Engineered changes in 
the proteins have attenuated receptor binding and biological activity 
to an essentially nonspecific level. The vaccines retain a high degree 
of antigenicity and have been successfully tested in murine and 
nonhuman primate animal models for protective immunity and safety. 
These vaccines offer the safety and advantages of defined recombinant 
proteins and may be useful for controlling toxic-shock syndromes and 
certain autoimmune diseases associated with these bacterial 
superantigens.''
Gregory D. Showalter,
Army Federal Register Liaison Officer.
[FR Doc. 97-22872 Filed 8-27-97; 8:45 am]
BILLING CODE 3710-08-M