[Federal Register Volume 62, Number 152 (Thursday, August 7, 1997)]
[Notices]
[Page 42558]
From the Federal Register Online via the Government Publishing Office [www.gpo.gov]
[FR Doc No: 97-20816]



[[Page 42558]]

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DEPARTMENT OF HEALTH AND HUMAN SERVICES

Office of the Secretary


Findings of Scientific Misconduct

AGENCY: Office of the Secretary, HHS.

ACTION: Notice.

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SUMMARY: Notice is hereby given that the Office of Research Integrity 
(ORI) has made a final finding of scientific misconduct in the 
following case:
    David N. Shapiro, M.D., St. Jude Children's Research Hospital: 
Based upon a report from St. Jude Children's Research Hospital as well 
as information obtained by the Office of Research Integrity (ORI) 
during its oversight review, ORI found that Dr. Shapiro, former faculty 
member, St. Jude Children's Research Hospital, engaged in scientific 
misconduct by falsifying the authorship of five publications listed in 
his biographical sketches in several National Institutes of Health 
(NIH) grant applications, including applications submitted to the 
National Institute of Arthritis and Musculoskeletal and Skin Diseases 
(NIAMS), the National Institute of General Medical Sciences (NIGMS), 
the National Institute of Diabetes and Digestive and Kidney Diseases 
(NIDDK), and the National Cancer Institute (NCI).
    Specifically, Dr. Shapiro listed himself as an author when he was 
not. Dr. Shapiro also fabricated data for Figures 5 and 7 in the 
following publication: Sublett, J.E., Jeon, I.S., & Shapiro, D.N. ``The 
aveolar rhabdomyosarcoma PAX3/FKHR fusion protein is a transcriptional 
activator.'' Oncogene 11:545-552, 1995. Dr. Shapiro has submitted a 
letter to Oncogene requesting retraction of these figures.
    Dr. Shapiro has accepted the ORI finding and has entered into a 
Voluntary Exclusion Agreement with ORI in which he has voluntarily 
agreed:
    (1) To exclude himself from serving in any advisory capacity to the 
Public Health Service (PHS), including but not limited to service on 
any PHS advisory committee, board, and/or peer review committee, or as 
a consultant for a period of three (3) years, beginning on July 29, 
1997;
    (2) To exclude himself from any contracting or subcontracting with 
any agency of the United States Government and from eligibility for, or 
involvement in, nonprocurement transactions (e.g., grants and 
cooperative agreements) of the United States Government as defined in 
45 CFR part 76 (Debarment Regulations) for a period of two (2) years, 
beginning on July 29, 1997;
    (3) That any institution that submits an application for PHS 
support for a research project on which Dr. Shapiro's participation is 
proposed or that uses him in any capacity on PHS supported research 
must concurrently submit a plan for supervision of his duties to the 
funding agency for approval for a period of one (1) year following the 
two (2) year exclusion. The supervisory plan must be designed to ensure 
the scientific integrity of Dr. Shapiro's research contribution. The 
institution also must submit a copy of the supervisory plan to ORI.

FOR FURTHER INFORMATION CONTACT: Acting Director, Division of Research 
Investigations, Office of Research Integrity, 5515 Security Lane, Suite 
700, Rockville, MD 20852, (301) 443-5330.
Chris B. Pascal,
Acting Director, Office of Research Integrity.
[FR Doc. 97-20816 Filed 8-6-97; 8:45 am]
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