[Federal Register Volume 62, Number 126 (Tuesday, July 1, 1997)]
[Notices]
[Pages 35516-35517]
From the Federal Register Online via the Government Publishing Office [www.gpo.gov]
[FR Doc No: 97-17200]


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DEPARTMENT OF HEALTH AND HUMAN SERVICES

National Institutes of Health


Proposed Collection; Comment Request; Transmission and Linkage 
Analysis of Alcoholism in a Southwestern American Indian Tribe; 
Collection of EEG Phenotypes Associated With Alcoholism

SUMMARY: In compliance with Section 3506(c)(2)(A) of the Paperwork 
Reduction Act of 1995, which provides for an opportunity for public 
comment on proposed data collection projects, the National Institute on 
Alcohol Abuse and Alcoholism (NIAAA), National Institutes of Health 
(NIH) will publish periodic summaries of proposed projects to be 
submitted to the Office of Management and Budget (OMB) for review and 
approval.

[[Page 35517]]

Proposed Collection

    The Laboratory of Neurogenetics (LN), Division of Intramural 
Clinical and Biological Research, NIAAA, intends to conduct the study 
for `Transmission and Linkage Analysis of Alcoholism in a Southwestern 
American Indian Tribe; Collection of EEG Phenotypes Associated with 
Alcoholism.'
    The LN is authorized by Section 452 of Part G of Title IV of the 
Public Health Service Act (42 U.S.C. 288) as amended by the NIH 
Revitalization Act of 1993 (Pub. Law 103-43). The information proposed 
for collection in this study will be used by the NIAAA to determine 
resting EEG and ERP phenotypes in large American Indian families, 
correlate this information with psychiatric diagnoses from previous 
studies, and perform linkage analysis in order to map the genes for 
these phenotypes which to appear to confer vulnerability to alcoholism 
in Caucasians. There are obvious great advantages in studying the large 
families the NIAAA already contacted, psychiatrically interviewed, and 
genotyped. The NIAAA hypothesizes that this EEG family study will 
enable elucidation of the transmission and linkage of alcoholism 
vulnerability in this tribe. The intent is to identify subgroups of 
American Indian alcoholics who may be more responsive to particular 
treatment of prevention strategies.
    The annual burden estimates are as follows:

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                                                               Responses                                        
               Type and number of respondents                     per         Total        Hours     Total hours
                                                               respondent   responses                           
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Clients--400................................................            1          400         2.25          900
Total Number of Respondents.................................  ...........          400  ...........  ...........
Total Number of Responses...................................  ...........          400  ...........  ...........
Total Hours.................................................  ...........          900  ...........  ...........
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Request for Comments

    Comments are invited on: (a) whether the proposed collection is 
necessary, including whether the information has practical use; (b) 
ways to enhance the clarity, quality, and use of the information to be 
collected; (c) the accuracy of the agency estimate of burden of the 
proposed collection; and (d) ways to minimize the collection burden of 
the respondents. Send written comments to Ms. Ronni Nelson, Laboratory 
of Neurogenetics, Division of Intramural Clinical and Biological 
Research, NIAAA, NIH, Park Bldg. Room 451, 12420 Parklawn Drive MSC 
8110, Rockville, Maryland 20852.

FOR FURTHER INFORMATION: To request more information on the proposed 
project or to obtain a copy of the data collection plans, contact Ms. 
Ronni Nelson, Laboratory of Neurogenetics, Division of Intramural 
Clinical and Biological Research, NIAAA, Park Bldg. Room 451, 12420 
Parklawn Drive MSC 8110, Rockville, Maryland 20852, or call non-toll-
free number (301) 443-5781.

COMMENTS DUE DATE: Comments regarding this information collection are 
best assured of having their full effect if received on or before 
September 2, 1997.

    Dated: June 19, 1997.
Martin K. Trusty,
Executive Officer, NIAAA.
[FR Doc. 97-17200 Filed 6-30-97; 8:45 am]
BILLING CODE 4140-01-M