[Federal Register Volume 62, Number 121 (Tuesday, June 24, 1997)]
[Notices]
[Pages 34066-34070]
From the Federal Register Online via the Government Publishing Office [www.gpo.gov]
[FR Doc No: 97-16475]


-----------------------------------------------------------------------

DEPARTMENT OF HEALTH AND HUMAN SERVICES

Centers for Disease Control and Prevention
[Announcement 772]


Hepatitis B Vaccination Evaluation Project in Vietnamese-American 
Children

Introduction

    The Centers for Disease Control and Prevention (CDC) announces the 
availability of funds in fiscal year (FY) 1997 for a cooperative 
agreement program to evaluate feasible methods of providing hepatitis B 
vaccine to children 3-16 years of age in the Vietnamese-American 
population in the United States.
    CDC is committed to achieving the health promotion and disease 
prevention objectives of Healthy People 2000, a national activity to 
reduce morbidity and mortality and improve the quality of life. This 
announcement is related to the priority area of Immunization and 
Infectious Diseases. (For ordering a copy of Healthy People 2000, see 
the Section Where to Obtain Additional Information.)

Authority

    This program is authorized under section 317 [42 U.S.C. 247b], of 
the Public Health Service Act, as amended.

Smoke-Free Workplace

    CDC strongly encourages all grant recipients to provide a smoke-
free workplace and promote the nonuse of all tobacco products, and 
Public Law 103-227, the Pro-Children Act of 1994, prohibits smoking in 
certain facilities that receive Federal funds in which education, 
library, day care, health care, and early childhood development 
services are provided to children.

Eligible Applicants

    Applications may be submitted by public and private nonprofit 
organizations and State governments and their agencies.

    Note: An organization described in section 501(c)(4) of the 
Internal Revenue Code of 1986 which engages in lobbying activities 
shall not be eligible to receive Federal funds constituting an 
award, grant, contract, loan, or any other form.

    Eligible applicants may enter into contractual agreements, as 
necessary, to meet the requirements of the program and to strengthen 
the overall application. The intent to use such mechanisms must be 
stated in the application and the nature and scope of work of these 
mechanisms require the approval of CDC.
    Awardee(s) must maintain the primary responsibility for conduct of 
the cooperative agreement. The awardee, as the direct and primary 
recipient of Federal funds, must perform a substantive role in carrying 
out project activities and not merely serve as a conduit for an award 
to another party or provide funds to an ineligible party. Applicants 
must justify the need to use a contractor. If contractors are proposed, 
the following must be provided: (1) Name of the contractor, (2) method 
of selection, (3) period of performance, (4) detailed budget, (5) 
justification for use of contractor, and (6) assurance of non-conflict 
of interest.

Availability of Funds

    Approximately $220,000 will be available in FY 1997 (for both 
direct and indirect costs) to fund one award. It is expected that the 
award will begin on or about September 30, 1997, for a 12-month budget 
period within a project period of up to 3 years. Funding estimates may 
vary and are subject to change.
    Continuation awards within the project period will be made on the 
basis of the following criteria:

1. Satisfactory progress in meeting program objectives.
2. Extent to which the continuation year objectives are realistic, 
specific, and measurable.
3. Extent to which proposed changes in program objectives, methods of 
operation, staff or contractor(s), or evaluation procedures will 
facilitate achievement of project goals.
4. Extent to which budget changes or requests are clearly justified and 
consistent with the intended use of cooperative agreement funds.
5. The availability of funds.

Use of Funds

Restrictions on Lobbying

    Applicants should be aware of restrictions on the use of HHS funds 
for lobbying of Federal or State legislative bodies. Under the 
provisions of 31 U.S.C. Section 1352 (which has been in effect since 
December 23, 1989), recipients (and their subtier contractors) are 
prohibited from using appropriated Federal funds (other than profits 
from a Federal contract) for lobbying Congress or any Federal agency in 
connection with the award of a particular contract, grant, cooperative 
agreement, or loan. This includes grants/cooperative agreements that, 
in whole or in part, involve conferences for which Federal funds cannot 
be used directly or indirectly to encourage participants to lobby or to 
instruct participants on how to lobby.
    In addition, the FY 1997 HHS Appropriations Act, which became 
effective October 1, 1996, expressly prohibits the use of 1997 
appropriated funds for indirect or ``grass roots'' lobbying efforts 
that are designed to support or defeat legislation pending before State 
legislatures. This new law, Section 503 of Pub. L. No. 104-208, 
provides as follows:

    Sec. 503(a) No part of any appropriation contained in this Act 
shall be used, other than for normal and recognized executive-
legislative relationships, for publicity or propaganda purposes, for 
the preparation, distribution, or use of any kit, pamphlet, booklet, 
publication, radio, television, or video presentation designed to 
support or defeat legislation pending before the Congress, * * * 
except in presentation to the Congress or any State legislative body 
itself.
    (b) No part of any appropriation contained in this Act shall be 
used to pay the salary or expenses of any grant or contract 
recipient, or agent acting for such recipient, related to

[[Page 34067]]

any activity designed to influence legislation or appropriations 
pending before the Congress or any State legislature.

    Department of Labor, Health and Human Services, and Education, and 
Related Agencies Appropriations Act, 1997, as enacted by the Omnibus 
Consolidated Appropriations Act, 1997, Division A, Title I, Section 
101(e), Pub. L. No. 104-208 (September 30, 1996).

Background

    Each year the hepatitis B virus (HBV) infects at least 150,000 
individuals in the United States and about 5,000 people die of the 
effects of chronic HBV infection. The risk of HBV infection and death 
in the Vietnamese community within the U.S. is about 10 times greater 
than for the remainder of the U.S. population. The full implementation 
of routine infant hepatitis B vaccination will eventually eliminate HBV 
transmission. However, a minimum of 20 years would be required to 
completely vaccinate all children by vaccinating infants alone. With 
the addition of recommendations for vaccination of adolescents by the 
age 11-12 years, at the current projected rate of less than one birth 
cohort per year, it will take at least 10 years to provide vaccine to 
all children. HBV transmission to unvaccinated children could be 
prevented by conducting ``catch-up'' hepatitis B vaccination programs 
in the children of first generation immigrants from countries of high 
or intermediate HBV endemicity. Vietnam is one of the countries with 
the highest endemicity levels where life-time risks of HBV infection in 
the unvaccinated approach 100 percent.
    Vietnamese are the fastest-growing Asian-Pacific Islander ethnic 
group in the United States. Bureau of Census projections for 1997 
indicate that there are 848,600 Vietnamese in the U.S. representing 8.4 
percent of the total Asian and Pacific Islander American (APIA) 
population and the largest South East Asian group in this country. 
Large groups of Vietnamese live in major urban clusters throughout the 
U.S., primarily in California, Texas, the metropolitan Washington, DC 
area, Washington State and Louisiana. The community infrastructure in 
these metropolitan areas is well established with Vietnamese specific 
television, radio, and print media markets. More than 88 percent of 
Vietnamese are foreign-born and 82 percent of those over 5 years of age 
speak Vietnamese at home.
    The prevalence of chronic HBV infection is high among Vietnamese in 
the U.S. Among those who arrived in the U.S. between 1984 and mid-1987, 
the prevalence rate was 14.4 percent, 28.8 times the rate in the U.S. 
general population (0.5 percent). Approximately one in seven Vietnamese 
is a chronic HBV carrier. It can be anticipated that two out of every 
hundred Vietnamese will die of hepatitis B-related liver disease.
    During 1995, demonstration projects in Philadelphia and San Diego 
have found vaccination rates in Vietnamese children 3-13 years of age 
of 4 percent and 15 percent, respectively. These demonstration projects 
were designed to serve all of the APIA groups in several selected 
communities that were predominantly South East Asian. The project staff 
found that methods which worked well with one Asian ethnic group often 
were not effective in another Asian ethnic group. Within 12 months, 
hepatitis B vaccination completion levels for the combined Asian ethnic 
groups, located in the targeted geographic areas, were raised to 20 
percent and 30 percent, respectively. The findings of these projects 
indicated that if it were possible, ethnic-group-specific health 
education methods should be identified and implemented to improve 
efficiency and effectiveness of hepatitis B vaccination catch-up 
efforts.
    These projects identified the need for health education related to 
hepatitis B in several areas. Among the key findings from these 
projects were that a substantial proportion of the medical 
professionals providing health care to the children of these 
communities were unaware (1) of the ACIP recommendations to vaccinate 
APIA 3-13 year old children with hepatitis B vaccine, (2) that the 
Federal Vaccines for Children (VFC) program provided free hepatitis B 
vaccine for these children (70 percent are eligible), and, (3) of the 
magnitude of the risk for HBV infection and resulting death these APIA 
children faced, compared to non-API children in the United States. 
Also, the majority of parents of these children were not aware of the 
HBV risks, the availability of a protective vaccine recommended for use 
in APIA, or of the VFC Program. These findings show the need to provide 
information to both the health professionals and the parents in these 
communities.
    On February 28, 1997, CDC convened a special Task Force of medical 
and public health professionals from around the country experienced in 
providing hepatitis B vaccination to APIA to ensure that a specific 
APIA vaccination goal will be attained. That goal is to raise hepatitis 
B vaccination rates in APIA children born from 1984 through 1993 from 
the current level of 10 percent to 90 percent by the close of the year 
2000. The efforts outlined in this announcement will help achieve this 
important goal.
    Hepatitis B virus transmission occurs at a higher rate in 
Vietnamese families because HBV infection has been endemic in most 
Asian populations for many centuries. Long before 1970 when the virus 
was first discovered the lifetime risk for HBV infection in these 
populations was almost 100 percent. From 10 percent to 20 percent of 
the pregnant women were chronically infected and passed the virus on to 
their infants at birth. Many of these infants became chronically 
infected. Many children born to women who did not have HBV infection 
were infected during childhood from exposure to other household members 
with chronic HBV infections. Therefore since this virus is transmitted 
by even small amounts of blood, transmission occurs easily within 
families--hence the label a ``family disease.'' Where someone in the 
family is chronically infected the other household members are very 
likely to eventually be infected as well. These children are exposed in 
the family and each successive generation was at higher risk than the 
previous one until the vaccine was developed in the early 1980's and 
now is being provided.

Purpose

    The purpose of the hepatitis B vaccination education evaluation 
project for Vietnamese children is to evaluate feasible methods of 
ensuring hepatitis B vaccination of children 3-16 years of age in the 
Vietnamese population within the United States, to create practical 
methods for implementation nationwide, and to estimate hepatitis B 
vaccination coverage rates in Vietnamese American children ages 3-16 
years of age.
    The goals of this demonstration project are:
    1. To evaluate and compare the effectiveness (including cost-
effectiveness) of two primarily different methods of ensuring hepatitis 
B vaccination of Vietnamese children age 3-16 years by (1) conducting 
baseline assessments of vaccination rates (coverage), (2) developing 
and applying the interventions, and (3) measuring the effectiveness of 
the interventions.
    2. To determine the factors that are most predictive of acceptance/
completion of the 3-dose hepatitis B vaccination series and the 
barriers associated with non-acceptance /non-completion in a defined 
target group of Vietnamese children age 3-16 years.
    The project will: (1) Provide health education resulting in 
hepatitis B

[[Page 34068]]

vaccination of 20,000 Vietnamese children in two of the largest 
Vietnamese communities in the United States, (2) provide a template to 
aid the national efforts to ensure hepatitis B vaccination for the 
estimated 292,756 Vietnamese-American children, (3) add to the existing 
knowledge about ``catch-up'' hepatitis B vaccination programs in 
Vietnamese communities across the nation, and (4) accurately measure 
hepatitis B vaccination coverage rates in children ages 3-16 years in 
three of the largest Vietnamese communities in the United States in 
1998 and again in the year 2000.

Program Requirements

    In conducting activities to achieve the purpose of this project, 
the recipient shall be responsible for the activities under A., below, 
and CDC shall be responsible for conducting activities under B., below:

A. Recipient Activities

    1. Develop and implement a research design that will evaluate the 
effectiveness of two separate and specific intervention methods. Apply 
methods, one each, in two separate Vietnamese communities with a third 
community serving as a comparison. The hepatitis B vaccination efforts 
in this third community should be comparable to those being conducted 
around the country. However, except for the pre-and post intervention 
telephone surveys conducted with a small random sample of parents, 
there will not be any added efforts in this comparison community.
    a. Conduct pre- and post-test measures in these three communities.
    b. Develop a media-based intervention exclusively, utilizing 
Vietnamese-language electronic, print and outdoor media.
    c. Utilize a community mobilization model which will include the 
formation of a coalition of community leaders and agencies which will 
conduct grass-roots, person-to-person community organizing activities.
    2. Promote the delivery of hepatitis B vaccine to all eligible 
Vietnamese children age 2-16 within the two target study communities 
through a network which may include public and private clinics, 
hospitals, and private doctors offices; Women, Infants and Children 
(WIC) and Aid to Families with Dependent Children (AFDC) sites as well 
as in day care centers, pre-schools, and elementary and high school 
based clinics; religious and community organizations; and through in-
home visitation and mobile vans.
    3. Follow published, scientifically valid methods of sample size 
and power calculations, sample selection, survey design, data 
collection, data management and data analysis.
    4. After completing the design, pretest and review phases, conduct 
a baseline household sample survey to measure hepatitis B vaccination 
levels and knowledge, attitudes, behaviors, and barriers related to 
hepatitis B vaccination.
    5. After conducting the baseline survey using the methods outlined 
in 2. above:
    a. Provide the culturally appropriate education on the risks of HBV 
infection and benefits of hepatitis B vaccination to all individuals in 
the two target study groups; and
    b. Inform all individuals in the two target study groups of the 
availability of free hepatitis B vaccinations for most 3-16 year old 
Vietnamese children in the two target study groups.
    6. Make available the information materials developed/modified and/
or evaluated during this project for use in similar populations 
throughout the United States as indicated.
    7. Develop a final report and prepare a manuscript in for 
submission to a peer reviewed journal for publication.
    8. Adhere to the detailed time-line provided by the recipient and 
approved by CDC which includes each major step necessary to accomplish 
the recipient activities listed above.
    9. Provide documentation of human subjects approval.

B. CDC Activities

    1. Provide scientific assistance needed to produce or adapt the 
educational materials to educate the community members.
    2. Provide technical assistance in regard to survey and other 
assessment and evaluation activities, analysis, manuscript development 
and other activities associated with the project.
    3. Coordinate meetings with recipients and representatives of other 
education/community outreach and evaluation projects.
    4. Provide technical assistance in the development of protocols for 
a community education and training program cooperatively with 
recipients.
    5. Provide information regarding CDC research projects related to 
hepatitis B vaccination in APIA communities.
    6. Collaborate with recipients on the use of media and coalition 
methods for community health education.

Technical Reporting Requirements

    Quarterly progress reports are required. An original and two copies 
of each report will be due 30 days after the end of each quarter. 
Submission due dates will be established at the time of the award. A 
financial status report (FSR) is due 90 days after the end of each 
budget period. An original and two copies of a final performance report 
and FSR are due no later than 90 days after the end of the project 
period.
    Progress reports and the final performance report must include the 
following:
    1. Restate each objective and under each address the progress made 
on each item listed under Program Requirements section in this 
announcement as well as each specific additional activity included in 
the recipient's accepted proposal.
    2. Under each objective list and explain any deviation from the 
time-line presented and approved in the recipient's accepted proposal; 
provide specific steps that are being or will be taken to return to the 
original agreed upon time-line.
    3. Under each objective list and explain any problems that have 
been encountered and the steps that have been or will be taken to 
overcome these problems.
    4. Include frequency tabulations for the key items in the surveys 
conducted during the reporting period.
    5. Succinctly describe and quantify presentations made during the 
reporting period related to the project.
    6. Include, in the appendix, estimates of the number of vaccine 
recipients by dose of hepatitis B vaccine administered.
    7. Include, in the appendix, copies of key correspondence regarding 
the demonstration project.
    8. Include, in the appendix, copies of all informational materials 
utilized in the community outreach components of this demonstration 
project.
    9. Include, in the appendix, copies of all survey instruments used 
or to be used in this demonstration project.
    10. Include any other activity or item felt by the project director 
to be pertinent.
    All reports must be submitted to Ron Van Duyne, Grants Management 
Officer, Attention: David Elswick, Grants Management Branch, 
Procurement and Grants Office, Centers for Disease Control and 
Prevention (CDC), 255 East Paces Ferry Road, NE., Room 300, Mailstop E-
13, Atlanta, GA 30305.

Application Content

    To assist in developing the application, applicants should use as 
guidance the information provided below and in the Evaluation Criteria

[[Page 34069]]

section of the announcement. The application must:
    1. Demonstrate that the applicant has the following:
    a. The ability and opportunity to evaluate three populations of at 
least 20,000 Vietnamese people each within a community or geographic 
area that can be defined and approached with a television media based 
immunization outreach program and which are similar on relevant 
characteristics such as demographic, geographic, social economic 
status, and health care profiles.
    b. Established links to the Vietnamese community with culturally 
appropriate and sensitive outreach methods.
    c. A history of successful completion of telephone survey research 
projects as part of medical or public health outreach programs within 
the Vietnamese community.
    d. Prior experience in the development and evaluation of effective 
perinatal and universal infant hepatitis B vaccination programs within 
the Vietnamese population.
    e. Culturally appropriate, commercial quality, topic specific 
video, audio, print, and outdoor media materials previously developed 
and tested in Vietnamese communities.
    2. Include a complete and detailed proposal that will serve as the 
plan and general protocol for the entire demonstration project. 
Applicants should provide a title page; a table of contents; an 
introduction section with goals and objectives; followed with a 
background section including complete but brief descriptions of the 
target populations and the current perinatal and routine infant 
hepatitis B vaccination programs in the target population; a methods 
section with educational methods, evaluation and analytic methods, 
goals and objectives of each survey as well as list of variables to be 
measured and questions to be answered by each survey; a detailed time-
line including all major steps and events; an appendix with (1) 
curricula vita of the managers and supervisors and principal 
investigator(s) with job descriptions of jobs that will be filled by 
the cooperative agreement monies; (2) a list of previous or ongoing 
similar projects conducted in this or similar communities showing the 
amount of funding, funding agencies, dates of the project, principal 
investigator, and a brief summary of each project; and (3) original 
letters of support including commitments to detailed activities with 
the appropriate signatures from a minimum of three major community 
groups working within the target population, the health care providers 
serving at least 80 percent of the target population, and a minimum of 
two school districts within the target population, as well as all 
subcontractors to be hired for any portion of the project.
    3. Provide the names, qualifications, and time allocations of the 
professional staff to be assigned to this project; the support staff 
available for the performance of this project; and the facilities and 
equipment available for performance of this project.
    4. If applicable, provide a description of any work that is to be 
performed by a subcontractor for the applicant. Proposed contracts 
should identify the name of the contractor, if known; describe the 
services to be performed; provide an itemized budget and justification 
for the estimated costs of the contract; specify the period of 
performance and method of selection.
    5. Provide evidence of collaboration with various groups necessary 
for the conduct of this project. These groups may include: community 
organizations, health care providers, and public health professionals 
from technical or academic centers with expertise in appropriate 
fields.
    6. Demonstrate partnerships with local or regional institutions 
that can assist in program implementation.
    7. The proposed budget should clearly indicate what proportion of 
each staff member's time is to be allocated to the project.
    8. While there is no legislative mandate for matching funds, all 
local matching resources should be shown with the proposed budget.
    9. Detailed budgets are not necessary for years two and three, but 
operational objectives should be included for years two and three of 
the project. Applicants should provide a detailed description of the 
proposed first year activities. Completed budget forms should be placed 
at the beginning of the application. Applicants should provide a 
detailed budget, with accompanying justification of all costs, that is 
consistent with the stated objectives and planned activities of the 
project. CDC may not approve or fund all proposed activities. 
Applicants should be precise about the program purpose of each budget 
item.
    The application pages must be clearly numbered and a complete index 
to the application and its appendices must be included. Each section of 
the proposal should be on a new page. The original and each copy of the 
application set must be submitted unstapled and unbound. All material 
must be typewritten, double spaced, with un-reduced type on 8\1/2\'' by 
11'' paper, with at least 1'' margins, and printed on one side only.

Evaluation Criteria

    The application will be reviewed and evaluated according to the 
following criteria:
    1. The extent to which the applicant's proposal: (a) Demonstrates 
the applicant's understanding of the purpose of the project and the 
feasibility of producing the required results; and (b) includes 
background information and other data to demonstrate that the applicant 
has the appropriate organizational structure, administrative support 
and accessibility to an adequate number of participants in the target 
populations to accomplish study objectives, including culturally 
appropriate outreach activities. (20%)
    2. The degree to which the plan of operation covers the ``Program 
Requirements'', is consistent with study goals and is realistic, 
specific, measurable and time-phased, and specifies the what, who, 
where, how and the timing for start and completion of each step. (20%)
    3. The degree to which the applicant's plan demonstrates the 
scientific soundness of the research methods and survey instruments to 
be used. (20%)
    4. The qualifications and commitment of the applicant; allocations 
of time and effort of staff devoted to the project; and the 
qualifications of the primary and support staff. (15%)
    5. The applicant's ability to collaborate with other agencies for 
conduct of the project, including the degree of commitment and 
cooperation of collaborating parties. (10%)
    6. The extent to which the applicant demonstrates a cultural 
competency for the proposed education, training, and telephone 
interviewing. (15%)
    7. The extent the proposed budget is reasonable, with a concise and 
clear justification, and consistent with the intended use of 
cooperative agreement funds. The application will also be reviewed as 
to the adequacy of existing and proposed facilities and resources for 
conducting project activities. (Not Scored)
    Site visits may be conducted before final funding decisions are 
made by CDC. Only the organizations with high ranking applications will 
be visited. During the visit, CDC staff will determine if all necessary 
components for start-up of the project are in place. This meeting will 
be conducted by the CDC representatives with participation by local 
staff and others who may have interest in this project. Periodic site 
visits will be held as indicated thereafter to monitor progress.

[[Page 34070]]

Executive Order 12372 Review

    Applications are subject to Intergovernmental Review of Federal 
Programs as governed by Executive Order (E.O.) 12372. E.O. 12372 sets 
up a system for State and local government review of proposed Federal 
assistance applications. Applicants should contact their State Single 
Point of Contact (SPOC) as early as possible to alert them to the 
prospective applications and receive any necessary instructions on the 
State process. For proposed projects serving more than one State, the 
applicant is advised to contact the SPOC for each affected State. A 
current list of SPOCs is included in the application kit. If SPOCs have 
any State process recommendations on applications submitted to CDC, 
they should send them to Ron Van Duyne, Grants Management Officer, 
Grants Management Branch, Procurement and Grants Office, Centers for 
Disease Control and Prevention (CDC), 255 East Paces Ferry Road, NE., 
Room 300, Mailstop E-13, Atlanta, GA 30305, no later than 30 days after 
the application deadline. The Announcement Number and Program Title 
should be referenced on the document. The granting agency does not 
guarantee to ``accommodate or explain'' the State process 
recommendations it receives after that date.

Public Health System Reporting Requirements

    This program is subject to the Public Health System Reporting 
Requirements. Under these requirements, all community-based 
nongovernmental applicants must prepare and submit the items identified 
below to the head of the appropriate State and/or local health 
agency(s) in the program area(s) that may be impacted by the proposed 
project no later than the receipt date of the Federal application. The 
appropriate State and/or local health agency is determined by the 
applicant. The following information must be provided:
    1. A copy of the face page of the application (SF424).
    2. A summary of the project that should be titled ``Public Health 
System Impact Statement'' (PHSIS), not to exceed one page, and include 
the following:
    a. A description of the population to be served;
    b. A summary of the services to be provided; and
    c. A description of the coordination plans with the appropriate 
State and/or local health agencies.
    If the State and/or local health official should desire a copy of 
the entire application, it may be obtained from the State Single Point 
of Contact (SPOC) or directly from the applicant.

Catalog of Federal Domestic Assistance Number

    The Catalog of Federal Domestic Assistance Number is 93.283.

Other Requirements

Surveys

    To document timely preparation and allow for input from CDC prior 
to implementation, DRAFTS of the pre-intervention baseline household 
survey questionnaire should be sent to CDC within two months of the 
initial notice of grant award date.
    A sampling plan for the household survey should be sent to CDC for 
review and comment prior to implementation. A draft of this plan should 
be sent in writing within one month of receipt of initial notice of 
grant award.

Human Subjects

    The proposed project involves research on human subjects, 
therefore, applicants must comply with the Department of Health and 
Human Services Regulations, 45 CFR part 46, regarding the protection of 
human subjects. Assurance must be provided to demonstrate the project 
will be subject to initial and continuing review by an appropriate 
institutional review committee. The applicant will be responsible for 
providing assurance in accordance with the appropriate guidelines and 
form provided in the application kit.

Application Submission and Deadline

    An original and two copies of the application PHS Form 5161-1 (OMB 
Number 0937-0189) must be submitted to Ron Van Duyne, Grants Management 
Officer, Attention: David Elswick, Grants Management Branch, 
Procurement and Grants Office, Centers for Disease Control and 
Prevention (CDC), 255 East Paces Ferry Road, NE., Room 300, Mailstop E-
13, Atlanta, GA 30305, on or before August 25, 1997.

1. Deadline

    The application shall be considered as meeting the deadline if it 
is either:
    a. Received on or before the deadline date, or
    b. Sent on or before the deadline date and received in time for 
submission to the objective review group. Applicant must request a 
legibly dated U.S. Postal Service postmark or obtain a legibly dated 
receipt from a commercial carrier or the U.S. Postal Service. Private 
metered postmarks shall not be acceptable as proof of timely mailing.

2. Late Applications

    Applications which do not meet the criteria in 1.a. or 1.b. above 
are considered late applications. A late application will not be 
considered and will be returned to the applicant.

Where To Obtain Additional Information

    A complete program description, information on application 
procedures, an application package, and business management technical 
assistance may be obtained from David Elswick, Grants Management 
Specialist, Grants Management Branch, Procurement and Grants Office, 
Centers for Disease Control and Prevention (CDC), 255 East Paces Ferry 
Road, NE., Room 300, Mailstop E-13, Atlanta, GA 30305, telephone (404) 
842-6521, Internet address: DCE[email protected].
    Programmatic technical assistance may be obtained from Gary L. 
Euler, DrPH, Chief, Hepatitis Activity, Adult Vaccine Preventable 
Diseases Branch, Epidemiology and Surveillance Division, National 
Immunization Program, Centers for Disease Control and Prevention (CDC), 
1600 Clifton Road NE. Mailstop E-61, Atlanta, GA 30333, telephone (404) 
639-8742, Internet address: GLE[email protected].
    Please refer to Announcement 772 when requesting information and 
submitting an application.
    A copy of ``Healthy People 2000'' (Full Report; Stock No. 017-001-
00474-0) or ``Healthy People 2000'' (Summary Report; Stock No. 017-001-
00473-1) referenced in the Introduction may be obtained through the 
Superintendent of Documents, Government Printing Office, Washington, DC 
20402-9325, telephone (202) 512-1800.

    Dated: June 18, 1997.
Joseph R. Carter,
Acting Deputy Associate Director for Management and Operations, Centers 
for Disease Control and Prevention (CDC).
[FR Doc. 97-16475 Filed 6-23-97; 8:45 am]
BILLING CODE 4163-18-P