[Federal Register Volume 62, Number 62 (Tuesday, April 1, 1997)]
[Rules and Regulations]
[Page 15389]
From the Federal Register Online via the Government Publishing Office [www.gpo.gov]
[FR Doc No: 97-55503]
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DEPARTMENT OF HEALTH AND HUMAN SERVICES
Food and Drug Administration
21 CFR Part 74
Listing of Color Additives Subject to Certification
CFR Correction
In title 21 of the Code of Federal Regulations, parts 1 to 99,
revised as of April 1, 1996, on page 369, in Sec. 74.2101 a portion of
the text for paragraph (a) was inadvertently removed. Paragraph (a)
should read as follows:
Sec. 74.2101 FD&C Blue No. 1.
(a) Identity. The color additive FD&C Blue No. 1 is principally the
disodium salt of ethyl[4-[p-[ethyl(m-sulfobenzyl)amino]--(o-
sulfophenyl)benzylidene]-2,5-cyclohexadien-1-ylidene](m-
sulfobenzyl)ammonium hydroxide inner salt with smaller amounts of the
isomeric disodium salts of ethyl[4-[p-[ethyl(p-sulfobenzyl)amino]-
-(o-sulfophenyl)benzylidene]-2,5-cyclohexadien-1-ylidene](p-
sulfobenzyl)ammonium hydroxide inner salt and ethyl[4-[p-[ethyl(o-
sulfobenzyl)amino]--(o-sulfophenyl)benzylidene]-2,5-
cyclohexadien-1-ylidene](o-sulfobenzyl)ammonium hydroxide inner salt.
Additionally, FD&C Blue No. 1 is manufactured by the acid catalyzed
condensation of one mole of sodium 2-formylbenzenesulfonate with two
moles from a mixture consisting principally of 3-
[(ethylphenylamino)methyl] benzenesulfonic acid, and smaller amounts of
4-[(ethylphenylamino)methyl] benzenesulfonic acid and 2-
[(ethylphenylamino)methyl] benzenesulfonic acid to form the leuco base.
The leuco base is then oxidized with lead dioxide and acid, or with
dichromate and acid, or with manganese dioxide and acid to form the
dye. The intermediate sodium 2-formylbenzenesulfonate is prepared from
2-chlorobenzaldehyde and sodium sulfite.
[FR Doc. 97-55503 Filed 3-31-97; 8:45 am]
BILLING CODE 1505-01-D