[Federal Register Volume 61, Number 242 (Monday, December 16, 1996)]
[Notices]
[Pages 66052-66053]
From the Federal Register Online via the Government Publishing Office [www.gpo.gov]
[FR Doc No: 96-31781]


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DEPARTMENT OF HEALTH AND HUMAN SERVICES
National Institutes of Health


Proposed Collection; Comment Request; Clinical, Laboratory, and 
Epidemiologic Characterization of Individuals at High Risk of Cancer

SUMMARY: In compliance with the requirement of Section 3506(c)(2)(A) of 
the Paperwork Reduction Act of 1995, for opportunity for public comment 
on proposed extension of existing data collection projects, the 
National Cancer Institute (NCI), the National Institutes of Health 
(NIH) will publish periodic summaries of proposed projects to be 
submitted to the Office of Management and Budget (OMB) for review and 
approval.

PROPOSED COLLECTION: Title Clinical, Laboratory, and Epidemiologic 
Characterization of Individuals at High Risk of Cancer. Type of 
Information Collection Request: Extension of OMB No. 0925-0194 
(Expiration date 01/31/97). Need and Use of Information Collection: 
This ongoing research study will identify cancer-prone persons in order 
to learn about cancer risk and cancer causes in individuals and 
families. The primary objectives of this research study are to utilize 
clinical, laboratory, and epidemiologic approaches in studies of 
individuals and families at high risk of cancer to identify and further 
characterize cancer susceptibility factors. Respondents are members of 
families in which multiple cancers are thought to have occurred. 
Information about the occurrence of cancer is collected and reviewed to 
determine eligibility for further etiologic study. Participation is 
entirely voluntary. The findings will lead to a better understanding of 
the causes and risk factors for selected cancers, which may reduce 
cancer incidence, and promote the earlier diagnosis of some cancers. 
Frequency of Response: One time. Affected Public: Individuals or 
households. Type of Respondents: Adults. The annual reporting burden is 
as follows: Estimated Number of Respondents: 600 per year; Estimated 
Number of Responses per Respondent: 1; Average Burden Hours Per 
Response: .75; and Estimated Total Annual Burden Hours Requested: 450. 
The annualized cost to respondent is estimated at: $4,500. There are no 
Capital Costs to report. There are no Operating or Maintenance Costs to 
report.

REQUEST FOR COMMENTS: Written comments and/or suggestions from the 
public and affected agencies are invited on one or more of the 
following points: (1) Whether the proposed collection of information is 
necessary for the proper performance of the function of the

[[Page 66053]]

agency, including whether the information will have practical utility; 
(2) The accuracy of the agency's estimate of the burden of the proposed 
collection of information, including the validity of the methodology 
and assumptions used; (3) Ways to enhance the quality, utility, and 
clarity of the information to be collected; and (4) Ways to minimize 
the burden of the collection of information on those who are to 
respond, including the use of appropriate automated, electronic, 
mechanical, or other technological collection techniques or other forms 
of information technology.

FOR FURTHER INFORMATION:To request more information on this project or 
to obtain a copy of the data collection plans and instrument, write to 
Dr. Margaret Tucker, Chief, Genetic Epidemiology Branch, National 
Cancer Institute, NIH, Executive Plaza North, Room 439, 6130 Executive 
Blvd., Bethesda, MD 20892, or call non-toll-free number (301) 496-4375, 
or E-mail your request, including your address to: 
[email protected]

COMMENTS DUE DATE: Comments regarding this information collection are 
best assured of having their full effect if received on or before 
February 14, 1997.

    Dated: December 9, 1996.
Nancie L. Bliss,
OMB Project Clearance Liaison.
[FR Doc. 96-31781 Filed 12-13-96; 8:45 am]
BILLING CODE 4140-01-M