[Federal Register Volume 61, Number 76 (Thursday, April 18, 1996)]
[Notices]
[Pages 16925-16926]
From the Federal Register Online via the Government Publishing Office [www.gpo.gov]
[FR Doc No: 96-9526]



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DEPARTMENT OF HEALTH AND HUMAN SERVICES
National Institutes of Health


Submission for OMB Review; Comment Request; Familial Cancer and 
the BRCA1 Gene in the Jewish Community of Greater Washington

SUMMARY: Under the provisions of Section 3506(c)(2)(A) of the Paperwork 
Reduction Act of 1995, the National Cancer Institute (NCI), the 
National

[[Page 16926]]

Institutes of Health (NIH), has submitted to the Office of Management 
and Budget (OMB) a request to review and approve the information 
collection listed below. This proposed information collection was 
previously published in the Federal Register on November 3, 1995, page 
55845 and allowed 60 days for public comment. One public comment was 
received, requesting a copy of the NIH approved study protocol. The 
purpose of this notice is to allow an additional 30 days for public 
comment. The National Institutes of Health may not conduct or sponsor, 
and the respondent is not required to respond to, an information 
collection that has been extended, revised, or implemented on or after 
October 1, 1995, unless it displays a currently valid OMB control 
number.

PROPOSED COLLECTION: Title: Familial Cancer and the BRCA1 Gene in the 
Jewish Community of Greater Washington. Type of Information Collection 
Request: EXTENSION. Need and Use of Information Collection: This 
research study will determine how common a particular alteration in the 
BRCA1 gene occurs in Jewish individuals, and what the risk of cancer is 
in individuals who carry this alteration. With the assistance of Jewish 
community leaders in the Washington, D.C. area, Jewish volunteers will 
be recruited for the study. Volunteers will donate a small blood sample 
and complete a self-administered questionnaire. The questionnaire will 
include a brief personal medical history, and a detailed family history 
of cancer. Participants will be notified of the overall study results, 
which may include recommendations about genetic testing and the 
availability of testing programs. Frequency of Response: One-time. 
Affected Public: Individuals. Type of Respondents: Jewish adult 
volunteers. The annual reporting burden is as follows: Estimated Number 
of Respondents: 7,700; Estimated Number of Responses per Respondent: 1; 
Average Burden Hours per Respondent: .50; and Estimated Total Annual 
Burden Hours Requested: 3850. The annualized cost to respondents is 
estimated at: $38,500. There are no Capital Costs to report. There are 
no Operating or Maintenance Costs to report.

REQUEST FOR COMMENTS: Written comments and/or suggestions from the 
public and affected agencies are invited on one or more of the 
following points: (1) Whether the proposed collection of information is 
necessary for the proper performance of the functions of the agency, 
including whether the information shall have practical utility; (2) The 
accuracy of the agency's estimate of the burden of the proposed 
collection of information, including the validity of the methodology 
and assumptions used; (3) Ways to enhance the quality, utility, and 
clarity of the information to be collected; and (4) Ways to minimize 
the burden of the collection of information on those who are to 
respond, including the use of appropriate automated, electronic, 
mechanical, or other technological collection techniques or other forms 
of information technology.

DIRECT COMMENTS TO OMB: Written comments and/or suggestions regarding 
the item(s) contained in this notice, especially regarding the 
estimated public burden and associated response time, should be 
directed to the: Office of Management and Budget, Office of Regulatory 
Affairs, New Executive Office Building, Room 10235, Washington, D.C. 
20503, Attention: Desk Officer for NIH. To request more information on 
the proposed project or to obtain a copy of the data collection plans 
and instruments, contact: Dr. Jeffery P. Struewing, Principal 
Investigator, Genetic Epidemiology Branch, NCI, NIH, Building EPN Room 
439, 6130 Executive Blvd MSC 7372, Bethesda, MD 20892-7372, or call 
non-toll-free number (301) 496-4375 or E-mail your request, including 
your address to: [email protected].

COMMENTS DUE DATE: Comments regarding this information collection are 
best assured of having their full effect if received within 30-days of 
the date of this publication.

    Dated: April 1, 1996.
Philip D. Amoruso,
NCI Executive Officer.
[FR Doc. 96-9526 Filed 4-17-96; 8:45 am]
BILLING CODE 4140-01-M