[Federal Register Volume 61, Number 40 (Wednesday, February 28, 1996)]
[Notices]
[Pages 7517-7518]
From the Federal Register Online via the Government Publishing Office [www.gpo.gov]
[FR Doc No: 96-4524]



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ENVIRONMENTAL PROTECTION AGENCY
[FRL-5431-4]


PCBs: Cancer Dose-Response Assessment and Application to 
Environmental Mixtures

AGENCY: Environmental Protection Agency.

ACTION: Notice of availability.

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SUMMARY: This notice announces the availability of a report titled, 
PCBs` Cancer Dose-Response Assessment and Assessment and Application to 
Environmental Mixtures, External Review Draft, (EPA/600/P-96/001A). The 
National Center for Environmental Assessment (NCEA) of the Office of 
Research and Development developed this report, which is an external 
draft for review purposes only and does not constitute U.S. 
Environmental Protection Agency (EPA) policy. The report will not have 
official status or receive clearance as an EPA document until after 
peer review has taken place. The document is being made available at 
this time because of public interest in PCBs.

ADDRESSES: The document will be available on the Internet at http://
www.epa.gov/docs/ORD or for purchase from the National Technical 
Information Service, 5285 Port Royal Road, Springfield, VA 22161; 
telephone 703-487-4650; facsimile 703-321-8547. The NTIS order number 
is PB96-140603; the price is $19.50 for paper and $9.00 for microfiche. 
Copies will be available for inspection at the EPA libraries. The EPA 
Headquarters Library is located at 401 M Street, S.W., Washington, DC; 
the library is open Monday through Friday between 10 a.m. and 2 p.m., 
except for Federal holidays. Unfortunately, due to budget restrictions, 
printed copies of the document are not available from the National 
Center for Environmental Assessment.

FOR FURTHER INFORMATION CONTACT:
Dr. Jim Cogliano, National Center for Environmental Assessment/
Washington Office (8602), U.S. Environmental Protection Agency, 401 M 
Street, S.W., Washington DC 20460. Telephone: 202-260-3830; facsimile: 
202-260-3803; E-mail: [email protected].

SUPPLEMENTARY INFORMATION: The draft report updates the cancer dose-
response assessment for PCBs and shows how information on toxicity, 
disposition, and environmental processes can be considered together to 
evaluate health risks from PCB mixtures in the environment. Guidance is 
given on applying the assessment to environment mixtures, different 
exposure routes, partial lifetime exposure, and mixtures containing 
dioxin-like compounds. In 

[[Page 7518]]
the Spring, the Agency will convene an external peer-review panel for a 
workshop that will be announced in the Federal Register. After the peer 
review workshop, EPA will incorporate the panel's comments and issue a 
final report. The expected date for the final report is September 1, 
1996. At the same time, a summary of the final report will be loaded 
onto the Agency's on-line database, the Integrated Risk Information 
System (IRIS).

    Dated: February 16, 1996.
Joseph K. Alexander,
Deputy Assistant Administrator for Research and Development.
[FR Doc. 96-4524 Filed 2-27-96; 8:45 am]
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