[Federal Register Volume 60, Number 127 (Monday, July 3, 1995)]
[Notices]
[Pages 34546-34550]
From the Federal Register Online via the Government Publishing Office [www.gpo.gov]
[FR Doc No: 95-16235]



-----------------------------------------------------------------------

DEPARTMENT OF HEALTH AND HUMAN SERVICES
Public Health Service


National Toxicology Program (NTP) Board of Scientific Counselors' 
Meetings; Announcement of NTP Draft Technical Reports Projected for 
Public Review From June 1995 Through Summer 1998

    To earlier inform the public and allow interested parties to 
comment or obtain information on long-term toxicology and 
carcinogenesis studies prior to public peer review, the National 
Toxicology Program (NTP) again publishes in the Federal Register a 
current listing of draft Technical Reports projected for evaluation by 
the NTP Board of Scientific Counselors' Technical Reports Review 
Subcommittee during their next seven meetings from June 1995 through 
the summer of 1998. We plan to continue updating the listing with 
announcements in the Federal Register once or twice a year. The next 
meeting dates are June 20-21 and December 5-6, 1995. Specific dates for 
1996, 1997, and 1998 meetings will be established at a later time.
    The attached Table 1 lists draft Technical Reports for long-term 
studies on chemicals within known or approximate dates of reviews and 
includes Chemical Abstracts Service (CAS) registry numbers, primary 
use, route of administration, species, exposure levels, and NTP report 
numbers (if assigned).
    Technical Reports of short-term toxicity studies are currently 
reviewed by mail; however, they may be reviewed in open meetings when 
necessary. The attached Table 2 lists the draft Technical Reports of 
short-term toxicity studies tentatively projected for review by mail 
from May 1995 to October 1998 and also includes Chemical Abstracts 
Service (CAS) registry numbers, primary use, route of administration, 
species, exposure levels, and NTP report numbers (if assigned).
    Those interested in having more information about any of the 
studies listed in this announcement should contact Central Data 
Management as early as possible by telephone or by mail at: MD-A0-01, 
NIEHS, P.O. Box 12233, Research Triangle Park (RTP), North Carolina 
27709 (919/541-3419). The program would welcome receiving toxicology 
and carcinogenesis data from completed, ongoing or planned studies by 
others as well as current production data, human exposure information, 
and use and use patterns.
    The Executive Secretary, Dr. Larry G. Hart, P.O. Box 12233, 
Research Triangle Park, North Carolina 27709, telephone 919/541-3971, 
FAX 919/541-0719 will furnish final agendas and other program 
information prior to a meeting, and summary minutes subsequent to a 
meeting.

    Dated: June 16, 1995.
Kenneth Olden,
Director, National Toxicology Program.

 Table 1.--Summary Data for Technical Reports Scheduled for Review at the Meeting of the NTP Board of Scientific
            Counselors' Technical Reports Review Subcommittee from June 20, 1995 through Summer 1998            
----------------------------------------------------------------------------------------------------------------
                                                                                                            NTP 
        Chemical name/cas No.            Use       Route     Species            Exposure levels              Tr 
                                                                                                            No. 
----------------------------------------------------------------------------------------------------------------
                        Chemicals Tentatively Scheduled for Peer Review June 20-21, 1995                        
                                                                                                                
----------------------------------------------------------------------------------------------------------------
BUTYL BENZYL PHTHALATE; 85-68-7.....  PLAS      FEED        RR        MR: 0, .3%, .6%, OR 1.2%; 60/GROUP     458
                                                                       FR: 0, .6%, 1.2%, OR 2.4%; 60/           
                                                                       GROUP.                                   
T-BUTYLHYDROQUINONE; 1948-33-0......  FOOD      FEED        RMR       R&M: 0, 0.125, 0.25, OR 0.5% IN        459
                                                                       FEED; 70 RATS, 60 MICE.                  
CODEINE; 76-57-3....................  PHAR      FEED        RM        R: 0, 400, 800, OR 1600 M: 0, 750,    455 
                                                                       1500, OR 3000 PPM; 60/GROUP.             

[[Page 34547]]
                                                                                                                
1,2-DIHYDRO-2,2,4-TRIMETHYLQUINOLINE  RUBR      SP          RMM       RATS: 0, 60, OR 100 MG/KG MICE: 0,     455
 (MONOMER); 147-47-7.                                                  6, OR 10 MG/KG (CORE).                   
1,2-DIHYDRO-2,2,4-TRIMETHYLQUINOLINE  RUBR      SP          RM        RATS: 0, 36, 60, OR 100 MG/KG MICE:    456
 (MONOMER); 147-47-7.                                                  0, 3.6, 6.0, OR 10.0 MG/KG.              
FEED RESTRICTION STUDIES............  ........  ..........  RM        Effect of dietary restriction on       460
                                                                       toxicology and carcinogenesis            
                                                                       studies in F344/N rats and B6C3F1        
                                                                       mice.                                    
SALICYLAZOSULFAPYRIDINE; 599-79-1...  PHAR      GAV         RM        R: 84, 168, OR 337.5 MG/KG; 70/        457
                                                                       GROUP M: 675, 1350, OR 2700 MG/KG;       
                                                                       60/GROUP.                                
SCOPOLAMINE HYDROBROMIDE TRIHYDRATE;  PHAR      GAV         RMM       R&M: 0,1,5, OR 25 MG/KG; 70/GROUP      445
 6533-68-2.                                                            DIET RESTRICTION MICE: 0 OR 25 MG/       
                                                                       KG;70/GROUP.                             
                                                                                                                
----------------------------------------------------------------------------------------------------------------
                       Chemicals Tentatively Scheduled for Peer Review December 5-6, 1995                       
                                                                                                                
----------------------------------------------------------------------------------------------------------------
D & C YELLOW NO. 11; 8003-22-3......  DYE       FEED        R         RATS: 0, 0.05, 0.17, OR 0.5%; 60/    .....
                                                                       GROUP.                                   
MOLYBDENUM TRIOXIDE; 1313-27-5......  METL      INHAL       RM        R&M: 10, 30, OR 100 MG/M3; 50/SEX/   .....
                                                                       SPECIES/GROUP.                           
NITROMETHANE; 75-52-5...............  FUEL      INHAL       RM        R: 0, 94, 188, OR 375 PPM; 50/GROUP  .....
                                                                       M: 0, 188, 375, OR 750 PPM; 50/          
                                                                       GROUP.                                   
PHENOLPHTHALEIN; 77-09-8............  PHAR      FEED        RM        R: 0, 1.2, 2.5, OR 5%; M: 0, 0.3,    .....
                                                                       0.6, OR 1.2% IN FEED (50/SEX/            
                                                                       SPECIES/GROUP).                          
SODIUM XYLENESULFONATE; 1300-72-7...  DTRG      SP          RM        R: 0, 60, 120, OR 240 MG/KG M: 0,    .....
                                                                       182, 364, OR 727 MG/KG (50/SEX/          
                                                                       GROUP).                                  
TETRAFLUOROETHYLENE; 116-14-3.......  FOOD      INHAL       RM        MICE & FR: 0, 312, 625, OR 1250 MR:  .....
                                                                       0, 156, 312, OR 625 PPM; 50/GROUP.       
                                                                                                                
----------------------------------------------------------------------------------------------------------------
                          Chemicals Tentatively Scheduled for Peer Review Summer 1996                           
                                                                                                                
----------------------------------------------------------------------------------------------------------------
ETHYLBENZENE; 100-41-4..............  RUBR      INHAL       RM        R&M: 0, 75, 250, OR 750 PPM (50/SEX/ .....
                                                                       SPECIES/GROUP).                          
INTERFERON AD+3'-AZIDO-3'-            PHAR      SC&GV       MM        DUAL ROUTES WITH BOTH COMPOUNDS:     .....
 DEOXYTHYMIDINE (AIDS INITIATIVE)                                      AZT: 0, 30, 60, OR 120 (GAV) MG/         
 INTAZTCOMB.                                                           KG; IFN: 500 OR 5000 UNITS 3X/WEEK.      
OXAZEPAM; 604-75-1..................  PHAR      FEED        R         0, 625, 1250, 2500, 5000, OR 10000        
                                                                       PPM; 50/SEX/GROUP.                       
                                                                                                                
----------------------------------------------------------------------------------------------------------------
                           Chemicals Tentatively Scheduled for Peer Review Fall 1996                            
                                                                                                                
----------------------------------------------------------------------------------------------------------------
DIETHANOLAMINE; 111-42-2............  TEXL      SP          RM        MR: 0, 16, 32, OR 64 MG/KG; FR: 0,   .....
                                                                       8, 16, OR 32 MG/KG; MICE: 0, 40,         
                                                                       80, OR 160 MG/KG (50/SEX/SPECIES/        
                                                                       GROUP).                                  
TETRAHYDROFURAN; 109-99-9...........  SOLV      INHAL       RM        R&M: 0, 200, 600, OR 1800 PPM (50/   .....
                                                                       SEX/SPECIES/GROUP).                      
THEOPHYLLINE; 58-55-9...............  PHAR      GAV         RM        R: 7.5, 25, OR 75 MG/KG; 50/GROUP    .....
                                                                       FM: 7.5, 25, OR 75 MG/KG; 50/GROUP       
                                                                       MM: 15, 50, OR 150 MG/KG; 50/GROUP.      
                                                                                                                
----------------------------------------------------------------------------------------------------------------
                          Chemicals Tentatively Scheduled for Peer Review Summer 1997                           
                                                                                                                
----------------------------------------------------------------------------------------------------------------
1-CHLORO-2-PROPANOL, TECHNICAL; 127-  INTR      WATER       RM        R: 0, 150, 325, OR 650 PPM M: 0,     .....
 00-4.                                                                 250, 500, OR 1000 PPM (50/SEX/           
                                                                       GROUP).                                  
PYRIDINE; 110-86-1..................  SOLV      WATER       RMR       R: 0, 100, 200, OR 400 PPM MM: 0,    .....
                                                                       250, 500, OR 1000 PPM FM: 125,           
                                                                       250, OR 500 PPM MWR: 0, 100, 200,        
                                                                       OR 400 PPM (50/SEX/GROUP).               
                                                                                                                
----------------------------------------------------------------------------------------------------------------
                           Chemicals Tentatively Scheduled for Peer Review Fall 1997                            
                                                                                                                
----------------------------------------------------------------------------------------------------------------
COCONUT OIL ACID DIETHANOLAMINE       TEXL      SP          RM        R: 0, 50, OR 100 MG/KG M: 0, 100,    .....
 CONDENSATE; 68603-42-9.                                               OR 200 MG/KG (50 SEX/SPECIES/            
                                                                       GROUP).                                  
FURFURYL ALCOHOL; 98-00-0...........  FOOD      INHAL       RM        R&M: 0, 2, 8, OR 32 PPM (50/SEX/     .....
                                                                       SPECIES/GROUP).                          
LAURIC ACID DIETHANOLAMINE            DTRG      SP          RM        R: 0, 50, OR 100 MG/KG M: 0, 100,    .....
 CONDENSATE; 120-40-1.                                                 OR 200 MG/KG (50/SEX/SPECIES/            
                                                                       GROUP).                                  

[[Page 34548]]
                                                                                                                
OLEIC ACID DIETHANOLAMINE             COS       SP          RM        R: 0, 50, OR 100 MG/KG; 50/SEX/      .....
 CONDENSATE; 93-83-4.                                                  GROUP M: 0, 15, OR 30 MG/KG; 55/         
                                                                       SEX/GROUP.                               
PENTACHLOROPHENOL, PURIFIED; 87-86-5  PEST      FEED        R         R: 0, 200, 400, OR 600 PPM; 50/SEX/  .....
                                                                       GROUP--1000 PPM STOP STUDY (60/          
                                                                       SEX).                                    
POLYVINYL ALCOHOL; 9002-89-5........  PHAR      IVAG        M         25% PVA, VEHICLE, UNTREATED; 100/    .....
                                                                       GROUP.                                   
PRIMACLONE; 125-33-7................  PHAR      FEED        RM        M: 0, 0.03, 0.06, OR 0.13% R: 0,     .....
                                                                       0.06, 0.13, OR 0.25% (50/SEX/            
                                                                       SPECIES).                                
                                                                                                                
----------------------------------------------------------------------------------------------------------------
                          Chemicals Tentatively Scheduled for Peer Review Summer 1998                           
                                                                                                                
----------------------------------------------------------------------------------------------------------------
ETHYLENE GLYCOL MONOBUTYL ETHER       SOLV      INHAL       RM        R: 0, 31, 62.5, OR 125 PPM M: 0,     .....
 (EGMBE); 111-76-2.                                                    62.5, 125, OR 250 PPM; 50/SEX/           
                                                                       SPECIES.                                 
GALLIUM ARSENIDE; 1303-00-0.........  ELEC      INHAL       RM        R: 0, 0.01, 0.1, OR 1.0 MG/M3; 50/   .....
                                                                       SEX/GROUP M: 0, 0.1, 0.5, OR 1.0         
                                                                       MG/M3; 50/SEX/GROUP.                     
ISOBUTENE; 115-11-7.................  RUBR      INHAL       RM        R&M: 0, 500, 2000, OR 8000 PPM (50/  .....
                                                                       SEX/SPECIES/GROUP).                      
ISOPRENE; 78-79-5...................  RUBR      INHAL       RM        R: 0, 220, 700, OR 7000 PPM; 50/SEX/ .....
                                                                       GROUP.                                   
METHYLEUGENOL; 93-15-2..............  FOOD      GAV         RM        R&M: 0, 37, 75, OR 150 MG/KG (50/    .....
                                                                       SEX/SPECIES/GROUP).                      
OXYMETHOLONE; 434-07-1..............  PHAR      GAV         RM        MR: 0, 3, 30, OR 150 MG/KG; FR: 0,   .....
                                                                       3, 30, OR 100 MG/KG.                     
----------------------------------------------------------------------------------------------------------------



   Table 2.--Short-Term Toxicity Studies Scheduled for Peer Review by the NTP Board of Scientific Counselors'   
                    Technical Reports Review Subcommittee from May 1995 through October 1998                    
----------------------------------------------------------------------------------------------------------------
                                                                                                            NTP 
        Chemical name/cas No.            Use       Route     Species            Exposure levels             Tox 
                                                                                                            No. 
----------------------------------------------------------------------------------------------------------------
                         Short-Term Toxicity Studies Scheduled for Peer Review May 1995                         
                                                                                                                
----------------------------------------------------------------------------------------------------------------
Halogenated Ethanes Class Study:                                                                                
  1,2-DICHLORO-1,1-DIFLUOROETHANE;    IND       GAV         R         MALE RATS 0, 0.62, 1.24 MMOL/KG/        45
   1649-08-7.                                                          DAY; 5/GRP.                              
  1,2-DIFLUROR-1,1,2,2-               SOLV      GAV         R         MALE RATS 0, 0.62, 1.24 MMOL/KG/        45
   TETRACHLOROETHANE; 76-12-0.                                         DAY; 5/GRP.                              
  HEXACHLOROETHANE; 67-72-1.........  SOLV      GAV         R         MALE RATS 0, 0.62, 1.24 MMOL/KG/        45
                                                                       DAY; 5/GRP.                              
  PENTABROMOETHANE; 75-95-6.........  IND       GAV         R         MALE RATS 0, 0.62, 1.24 MMOL/KG/        45
                                                                       DAY; 5/GRP.                              
  PENTACHLOROETHANE; 76-01-7........  SOLV      GAV         R         MALE RATS 0, 0.62, 1.24 MMOL/KG/        45
                                                                       DAY; 5/GRP; FEMALE RATS 0, 1,24          
                                                                       MMOL/KG/DAY;.                            
  1,1,1,2-TETRABROMOETHANE; 630-16-0  IND       GAV         R         MALE RATS 0, 0.62, 1.24 MMOL/KG/        45
                                                                       DAY; 5/GRP.                              
  1,1,2,2-TETRABROMOETHANE; 79-27-6.  FLAM      GAV         R         MALE RATS 0, 0.62, 1.24 MMOL/KG/        45
                                                                       DAY; 5/GRP.                              
  1,1,1,2-TETRACHLOROETHANE; 630-20-  INTR      GAV         R         MALE RATS 0, 0.62, 1.24 MMOL/KG/        45
   6.                                                                  DAY; 5/GRP.                              
  1,1,2,2-TETRACHLOROETHANE; 79-34-5  SOLV      GAV         R         MALE RATS 0, 0.62, 1.24 MMOL/KG/        45
                                                                       DAY; 5/GRP.                              
  1,1,1-TRICHLOROETHANE; 71-55-6....  SOLV      GAV         R         MALE RATS 0, 0.62, 1.24 MMOL/KG/        45
                                                                       DAY; 5/GROUP.                            
  1,1,1-TRICHLORO-2,2,2-              IND       GAV         R         MALE RATS 0, 0.62, 1.24 MMOL/KG/        45
   TRIFLUOROETHANE; 354-58-5.                                          DAY; 5/GRP.                              
  METHYL ETHYL KETOXIME; 96-29-7....  PNT       WATER       RM        R&M: 0, 625, 1250, 2500, 5000, OR       51
                                                                       10000 PPM; 10/GROUP.                     
                                                                                                                
----------------------------------------------------------------------------------------------------------------
                         Short-Term Toxicity Studies Scheduled for Peer Review June 1995                        
                                                                                                                
----------------------------------------------------------------------------------------------------------------
1,4-BUTANEDIOL; 110-63-4............  INTR      ..........  ........  Review of metabolism and                54
                                                                       disposition studies and prediction       
                                                                       of lack of carcinogenicity in long-      
                                                                       term studies..                           
METHAPYRILENE HYDROCHLORIDE; 135-23-  PHAR      FEED        R         MALE RATS: 0, 50, 100, 250, 1000        46
 9.                                                                    PPM; 40/GRP.                             
O-NITROTOLUENE; 88-72-2.............  RUBR      FEED        R         MALE R: 0, 0 ALTERED MICROFLORA 20/     44
                                                                       GRP; 5000 PPM 60/GRP; 5000 PPM           
                                                                       ALTERED MICROFLORA 40/GRP.               
O-TOLUIDINE HYDROCHLORIDE; 636-21-5.  DYE       FEED        R         O AND 0 ALTERED MICROFLORA; 20/GRP;     44
                                                                       5000 PPM; 60/GRP.                        
1,1,1-TRICHLOROETHANE; 71-55-6......  SOLV      MICRO       RM        R&M: 0, 0.5, 1.0, 2.0, 4.0, AND 8.0     41
                                                                       % (10/S/S).                              
URETHANE; 51-79-6...................  PNT       WATER       RM        R&M: (DEIONIZED WATER VEHICLE)          52
                                                                       0.011, 0.033, 0.11, 0.33, OR 1.0 G/      
                                                                       100 ML.                                  

[[Page 34549]]
                                                                                                                
URETHANE + ETHANOL (COMBINATION)      PNT       WATER       RM        R&M:(WITH 5% ETHANOLIN WATER)           52
 URETHCOMB.                                                            0.011, 0.033, 0.11, 0.33, OR 1.0 G/      
                                                                       100 ML.                                  
                                                                                                                
----------------------------------------------------------------------------------------------------------------
                       Short-Term Toxicity Studies Scheduled for Peer Review August 1995                        
                                                                                                                
----------------------------------------------------------------------------------------------------------------
CIS & TRANS 1,2-DICHLOROETHYLENE;     SOLV      MICRO       RM                                                55
 540-59-0.                                                                                                      
CIS-1,2-DICHLOROETHYLENE; 156-59-2..  SOLV      MICRO       RM                                                55
TRANS-1,2-DICHLOROETHYLENE; 156-60-5  SOLV      MICRO       RM                                                55
TRANS-1,2-DICHLOROETHYLENE; 156-60-5  SOLV      GAV         RM                                               55 
                       Short-Term Toxicity Studies Scheduled for Peer Review November 1995                      
                                                                                                                
----------------------------------------------------------------------------------------------------------------
M-CHLOROANILINE; 108-42-9...........  INTR      GAV         RM        R&M 0, 10, 20, 40, 80, 160 MG/KG,       43
                                                                       20/GRP (RATS); 10/GRP (MICE).            
O-CHLOROANILINE; 95-51-2............  DYE       GAV         RM        R&M 0, 10, 20, 40, 80, & 160 MG/KG;     43
                                                                       20/GRP (RATS);10/GRP (MICE).             
                                                                                                                
----------------------------------------------------------------------------------------------------------------
                         Short-Term Toxicity Studies Scheduled for Peer Review March 1996                       
                                                                                                                
----------------------------------------------------------------------------------------------------------------
3,3',4,4'-TETRACHLOROAZOXYBENZENE;    COMT      GAV         RM        R&M: 0, 0.1, 1.0, 3.0, 10, OR 30 MG/ .....
 21232-47-3.                                                           KG BODY WEIGHT (M&F 10/GROUP).           
                                                                                                                
----------------------------------------------------------------------------------------------------------------
                        Short-Term Toxicity Studies Scheduled for Peer Review June 1996                         
                                                                                                                
----------------------------------------------------------------------------------------------------------------
AZT+METHADONE HCL (AIDS) AZTMETHCOMB  PHAR      GAV         MM        AZT: 200, 400, OR 800 MG/KG/DAY      .....
                                                                       WITH METHADONE HCL: 5, 15, OR 30         
                                                                       MG/KG/DAY.                               
2',3'-DIDEOXYCYTIDINE (AIDS           PHAR      GAV         MM        FEMALE MICE ONLY: 500, 1000 MG/KG/   .....
 INITIATIVE); 7481-89-2.                                               DAY.                                     
3,3',4,4'-TETRACHLOROAZOBENZENE;      HERB      GAV         RM        R&M: 0, 0.1, 1.0, 3.0, 10, OR 30 MG/ .....
 14047-09-7.                                                           KG BODY WEIGHT (M&F 10/GROUP).          
1,1,2,2-TETRACHLOROETHANE; 79-34-5..  SOLV      MICRO       RM                                             .....
1,1,2,2-TETRACHLOROETHANE; 79-34-5..  SOLV      GAV         RM                                             .....
1,1,2,2-TETRACHLOROETHANE; 79-34-5..  SOLV      MICRO       RM        R&M R:UNTREATED CONTROL, VEHICLE    .....
                                                                       CONTROL, 18, 37, 75, 150, OR 300         
                                                                       MG/KG BODY WT/DAY; M:UNTREATED           
                                                                       CONTROL, VEHICLE CONTROL, 88, 175,       
                                                                       350, 700, OR 1400 MG/KG BODY WT/         
                                                                       DAY; 10/GROUP/SEX.                       
                                                                                                                
----------------------------------------------------------------------------------------------------------------
                       Short-Term Toxicity Studies Scheduled for Peer Review October 1998                       
                                                                                                                
----------------------------------------------------------------------------------------------------------------
INDIUM PHOSPHIDE; 22398-80-7........  ELEC      INHAL       RM        R&: 0, 1, 3, 10, 30, OR 100 MG/M3;   .....
                                                                       10/SEX/GROUP.                            
MAGNETIC FIELDS (EMF); ELECTROMAG...  ELEC      WB          RM        60 HZ MAGNETIC FIELDS--20 MG, 2 G,   .....
                                                                       10 G CONTINUOUS AND 10 G                 
                                                                       INTERMITTENT; 10/GROUP.                  
RETROVIRAL VECTORS RETROVIRVECT.....  PHAR      IP/IJ       RM        VARIOUS REGIMENS AND CONTROLS        .....
                                                                       INCLUDED.                                
----------------------------------------------------------------------------------------------------------------
Abbreviations used in this report:                                                                              
USE Primary Use Category:                                                                                       
COMT Contaminates and/or Impurities                                                                             
COSM Cosmetics, Perfumes, Fragrances, Hair Preparations, Skin Lotions                                           
DTRG Detergents and Cleansers                                                                                   
DYE As or in Dyes, Inks, and Pigments                                                                           
ELEC In Electrical and/or Dielectric Systems                                                                    
FLAM Flame Retardants                                                                                           
FOOD Food, Beverages, or Additives                                                                              
FUEL As or in Fuel or Oil Products                                                                              
HERB Herbicide(s)                                                                                               
IND Industrial Uses                                                                                             
INTR Chemical Intermediate or Catalyst                                                                          
METL Metals or in Metal Products                                                                                
PEST Pesticides, General or Unclassified                                                                        
PHAR Pharmaceuticals or Intermediates                                                                           
PLAS As or in Plastics                                                                                          
PNT Paint Ingredient                                                                                            
RUBR Rubber Chemical                                                                                            
SOLV Vehicles and Solvents                                                                                      
TEXL In Manufacture of Textiles                                                                                 
ROUTE Route of Administration:                                                                                  

[[Page 34550]]
                                                                                                                
FEED Dosed-Feed                                                                                                 
GAV Gavage                                                                                                      
INHAL Inhalation                                                                                                
IP/IJ Intraperitoneal Injection                                                                                 
IVAG Intravaginal                                                                                               
MICRO Microencapsulation in Feed                                                                                
SC&GV Subcutaneous Inj. + Gavage                                                                                
SP Topical                                                                                                      
WATER Dosed-Water                                                                                               
WB Whole Body Exposure                                                                                          
SPEC Species:                                                                                                   
R=Rats                                                                                                          
M=Mice                                                                                                          


[FR Doc. 95-16235 Filed 6-30-95; 8:45 am]
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