[Federal Register Volume 60, Number 79 (Tuesday, April 25, 1995)]
[Notices]
[Pages 20259-20260]
From the Federal Register Online via the Government Publishing Office [www.gpo.gov]
[FR Doc No: 95-10080]



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DEPARTMENT OF DEFENSE

Availability of Non-Exclusive, Exclusive, or Partially Exclusive 
Licensing of U.S. Patent Concerning a Method for Lysing Thrombi

AGENCY: U.S. Army Medical Research and Materiel Command, DOD.

ACTION: Notice.

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SUMMARY: In accordance with 37 CFR 404.6, announcement is made of the 
availability for licensing of U.S. Patent No. 5,399,158, entitled 
``Method of Lysing Thrombi'', and issued on March 21, 1995. This patent 
has been assigned to the United States Government as represented by the 
Secretary of the Army.

ADDRESSES: Commander, U.S. Army Medical Research and Materiel Command, 
ATTN: Command Judge Advocate, Fort Detrick, Frederick, Maryland 21702-
5012.

FOR FURTHER INFORMATION CONTACT:
Mr. John F. Moran, Patent Attorney, (301) 619-2065 or telefax (301) 
619-7714.

SUPPLEMENTARY INFORMATION: The invention describes an improved method 
for prevention or treatment of thrombosis, including deep venous 
thrombosis (DVT) and acute arterial thrombosis, such as coronary artery 
thrombosis, while avoiding damage to the surrounding tissue. The method 
includes the administration of plasminogen activators in conjunction 
with intermittent (pulse mode) ultrasound and the imposition of a 
fluid-containing barrier between the [[Page 20260]] ultrasound source 
and the patient's skin. It is also the purpose of the invention to 
provide a means for preventing formation of thrombi by administration 
of small doses of plasminogen-activating agents along with intermittent 
ultrasound of patients who are likely to suffer from formation of 
thrombi. Particularly at risk are older patients that are immobilized 
or patients whose injuries have caused decreased circulation in the 
extremities.
Gregory D. Showalter,
Army Federal Register Liaison Officer.
[FR Doc. 95-10080 Filed 4-24-95; 8:45 am]
BILLING CODE 3710-08-M