[Federal Register Volume 60, Number 16 (Wednesday, January 25, 1995)]
[Notices]
[Pages 4919-4920]
From the Federal Register Online via the Government Publishing Office [www.gpo.gov]
[FR Doc No: 95-1808]



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DEPARTMENT OF HEALTH AND HUMAN SERVICES
[CDC 520]


An International Collaborative Study of Cancer Risk Among Nuclear 
Industry Workers

Summary

    The Centers for Disease Control and Prevention (CDC) announces the 
availability of fiscal year (FY) 1995 funds for a cooperative agreement 
with the World Health Organization (WHO), International Agency for 
Research on Cancer (IARC), to plan and conduct an international, 
collaborative study of cancer risk among nuclear industry workers. 
Approximately $100,000 will be available in FY 1995 to fund the 
cooperative agreement. The award will begin on or about April 1, 1995, 
for a 12-month budget period within a project period of up to 5 years. 
Funding estimates may vary and are subject to change. Continuation 
award(s) within the project period will be made on the basis of 
satisfactory progress and the availability of funds.
    The purpose of this cooperative agreement is to assist the WHO, 
IARC, in further developing and strengthening epidemiologic research in 
order to promote the further understanding of the cancer risk 
associated with long-term, low-level occupational radiation exposure. 
The effort funded by this agreement will result in an improved 
understanding and quantification of the cancer risk encountered by 
United States workers in nuclear industries.
    CDC/NIOSH will provide assistance on program management and 
administrative matters related to the conduct of the scientific aspects 
of the cooperative agreement; technical and scientific consultation and 
assistance in the implementation of all epidemiologic activities 
conducted under the cooperative agreement; scientific consultation and 
assistance in formulating the research plan; and collaborate in the 
preparation of the scientific epidemiologic reports that result from 
the cooperative agreement.
    The Public Health Service (PHS) is committed to achieving the 
health promotion and disease prevention objectives of Healthy People 
2000, a PHS-led national activity to reduce morbidity and mortality and 
improve the quality of life. This announcement is related to the 
priority area of Occupational Safety and Health. (For ordering a copy 
of Healthy People 2000 see the section ``Where To Obtain Additional 
Information.'')

Authority

    This program is authorized under Section 301(a) of the Public 
Health Service Act (42 U.S.C. Section 241(a)) and Section 22(e)(7) of 
the Occupational Safety and Health Act (29 U.S.C. Section 671(e)(7)).

Smoke-Free Workplace

    The PHS strongly encourages all grant recipients to provide a 
smoke-free workplace and promote the non-use of all tobacco products. 
This is consistent with the PHS mission of promoting the protection and 
advancement of an individual's physical and mental health.

Eligible Applicant

    Assistance will be provided only to the WHO, IARC, Lyon, France, 
for this project. No other applications will be solicited. The program 
announcement and application kit have been sent to WHO, IARC. This 
organization is the only appropriate and qualified institution to 
provide the services specified under this cooperative agreement for the 
following reasons:
    1. Serving as the headquarters for international cancer research 
for the WHO, the IARC is the only organization with access to all the 
necessary data from the 14-member nations. No one in the United States 
or its territories has access to this data.
    2. The IARC serves as the cancer research arm of the WHO. Located 
in Lyon, France, the IARC was founded in 1965 and is responsible for 
conducting cancer epidemiologic research, disseminating information on 
cancer causes and prevention, and assisting countries in cancer control 
programs.
    3. The IARC has unique experience in planning and conducting 
cooperative international epidemiologic studies of workers in nuclear 
industries. In 1988, a collaborative study of over 250,000 nuclear 
workers was undertaken in the United States, the United Kingdom, and 
Canada. This study, now nearing completion, was coordinated through 
IARC.
    4. The IARC has already conducted a preliminary study demonstrating 
the feasibility of this investigation and has in place experts in 
epidemiology and radiation dosimetry who provided the technical 
assistance and guidance required for the study mentioned in 3 above. 
These technical experts will be available to plan and oversee this 
[[Page 4920]] epidemiologic study of almost 1,000,000 nuclear workers 
in 14 nations.
    5. Bringing together investigators from different countries is a 
well-developed practice at IARC. Most of their research on 
occupational, environmental or lifestyle hazards has been, or is 
presently being, conducted on an international basis. This provides the 
opportunity for a wide selection of populations suitable for 
epidemiologic investigation and facilitates the accumulation of large 
study populations, thus making the identification and quantification of 
cancer risk easier.

Executive Order 12372--Review

    The application is not subject to review under Executive Order 
12372.

Public Health System Reporting Requirements

    This program is not subject to the Public Health System Reporting 
Requirements.

Catalog of Federal Domestic Assistance Number

    The Catalog of Federal Domestic Assistance Number for this 
program is 93.283.

Other Requirements

Paperwork Reduction Act

    Projects that involve the collection of information from 10 or more 
individuals and funded by the cooperative agreement will be subject to 
review by the Office of Management and Budget (OMB) under the Paperwork 
Reduction Act.

Human Subjects

    If the proposed project involves research on human subjects, the 
applicant must comply with the Department of Health and Human Services 
Regulations, 45 CFR part 46, regarding the protection of human 
subjects. Assurance must be provided to demonstrate that the project 
will be subject to initial and continuing review by an appropriate 
institutional review committee. The applicant will be responsible for 
providing assurance in accordance with the appropriate guidelines and 
forms provided in the application kit.

Where To Obtain Additional Information

    If you are interested in obtaining additional information regarding 
this project, please refer to Announcement 520 and contact Oppie M. 
Byrd, Grants Management Specialist, Grants Management Branch, 
Procurement and Grants Office, Centers for Disease Control and 
Prevention (CDC), 255 East Paces Ferry Road, NE., Room 300, Mailstop E-
13, Atlanta, GA 30305, telephone (404) 842-6546.
    A copy of Healthy People 2000 (Full Report, Stock No. 017-001-
00474-0) or Healthy People 2000 (Summary Report, Stock No. 017-001-
00473-1) referenced in the ``Summary'' may be obtained through the 
Superintendent of Documents, Government Printing Office, Washington, DC 
20402-9325, telephone (202) 783-3238.

    Dated: January 19, 1995.
Richard A. Lemen,
Acting Director, National Institute for Occupational Safety and Health, 
Centers for Disease Control and Prevention (CDC).
[FR Doc. 95-1808 Filed 1-24-95; 8:45 am]
BILLING CODE 4163-19-P