[Federal Register Volume 59, Number 86 (Thursday, May 5, 1994)]
[Unknown Section]
[Page 0]
From the Federal Register Online via the Government Publishing Office [www.gpo.gov]
[FR Doc No: 94-10840]


[[Page Unknown]]

[Federal Register: May 5, 1994]


=======================================================================
-----------------------------------------------------------------------

ENVIRONMENTAL PROTECTION AGENCY

[FRL-4881-7]

 

Technical Review Workshop on the Reference Dose for Aroclor 1016

AGENCY: U.S. Environmental Protection Agency.

ACTION: Notice of meeting.

-----------------------------------------------------------------------

SUMMARY: This notice announces a workshop sponsored by the U.S. 
Environmental Protection Agency's (EPA's) Risk Assessment Forum to 
study the sceintific analysis underlying the Reference Dose (RfD) for 
Aroclor 1016, which appears on EPA's Integrated Risk Information System 
(IRIS). EPA will use recommendations developed at this meeting to re-
examine the RfD for Aroclor 1016.

DATES: The workshop will begin on Tuesday, May 24, 1994, at 8:30 a.m. 
and end on Wednesday, May 25, 1994, at 12 noon. Members of the public 
may attend as observers.

ADDRESSES: The Meeting will be held at the Barcelo Washington Hotel, 
2121 P Street, NW., Washington, DC.
    Eastern Research Group, Inc., an EPA contractor, is providing 
logistical support for the workshop. To attend the workshop as an 
observer, call Deborah Kanter, Eastern Research Group, Inc., 110 
Hartwell Avenue, Lexington, Massachusetts, 02173, Tel: 617/674-7320 by 
Friday, May 13, 1994. Space is limited.

FOR FURTHER INFORMATION CONTACT: Clare Stine, U.S. Environmental 
Protection Agency, Risk Assessment Forum (8101), 401 M Street, SW., 
Washington, DC 20460, Tel: (202) 260-6743.

SUPPLEMENTARY INFORMATION: Aroclor 1016 is a commercial mixture of 
polychorinated biphenyls devoid of dibenzofurans. In January 1993, 
based in part on a series of published reports on perinatal and long-
term neurobehavioral effects in monkeys, EPA entered an Aroclor 1016 
reference dose of 0.007 mg/kg-day into the Integrated Risk Information 
System. The IRIS entry states that, in general, the RfD is an estimate 
(with uncertainty spanning perhaps an order of magnitude) of a daily 
exposure to human populations that is likely to be without appreciable 
risk of deleterious effects during a lifetime.
    The purpose of the May 24-25 workshop is for EPA to collect expert 
opinions and recommendations from a panel of independent scientists 
regarding Aroclor 1016 data and the related IRIS entry. Although 
discussion of the RfD for any substance may present generic issues, 
this technical review meeting is limited to the science-based 
information and analyses relevant to Aroclor 1016. Larger issues 
regarding the generic RfD process are being addressed by the Agency as 
a separate effort (58 FR 11490; February 25, 1993).
    IRIS is an online database created by the Environmental Protection 
Agency and mounted on the National Library of Medicine's (NLM) 
Toxicology Data Network (TOXNET). Registered NLM online services users 
are able to access IRIS and all other TOXNET system files through the 
COMPUSERVE, TYMNET, TELENENT, or INFONET telecommunication net works or 
by direct dial.

    4Dated: April 29, 1994.
Gary J. Foley,
Assistant Administrator for Research and Development.
[FR Doc. 94-10840 Filed 5-4-94; 8:45 am]
BILLING CODE 6560-50-M