[Senate Report 118-253]
[From the U.S. Government Publishing Office]


                                                      Calendar No. 654
118th Congress     }                                     {      Report
                                 SENATE
 2d Session        }                                     {     118-253
_______________________________________________________________________

                                     

    

                     DETECT FENTANYL AND XYLAZINE 
                              ACT OF 2024

                               __________

                              R E P O R T

                                 of the

                   COMMITTEE ON HOMELAND SECURITY AND

                          GOVERNMENTAL AFFAIRS

                          UNITED STATES SENATE

                              to accompany

                                S. 4419

           TO REQUIRE THE SCIENCE AND TECHNOLOGY DIRECTORATE
           IN THE DEPARTMENT OF HOMELAND SECURITY TO DEVELOP
           GREATER CAPACITY TO DETECT, IDENTIFY, AND DISRUPT
             ILLICIT SUBSTANCES IN VERY LOW CONCENTRATIONS









    [GRAPHIC(S) NOT AVAILABLE IN TIFF FORMAT]











                December 2, 2024.--Ordered to be printed

                                   _______
                                   
                                   
                 U.S. GOVERNMENT PUBLISHING OFFICE 
                 
59-010                      WASHINGTON : 2025 


























        COMMITTEE ON HOMELAND SECURITY AND GOVERNMENTAL AFFAIRS

                   GARY C. PETERS, Michigan, Chairman
THOMAS R. CARPER, Delaware           RAND PAUL, Kentucky
MAGGIE HASSAN, New Hampshire         RON JOHNSON, Wisconsin
KYRSTEN SINEMA, Arizona              JAMES LANKFORD, Oklahoma
JACKY ROSEN, Nevada                  MITT ROMNEY, Utah
JON OSSOFF, Georgia                  RICK SCOTT, Florida
RICHARD BLUMENTHAL, Connecticut      JOSH HAWLEY, Missouri
LAPHONZA R. BUTLER, California       ROGER MARSHALL, Kansas

                   David M. Weinberg, Staff Director
                      Alan S. Kahn, Chief Counsel
         Christopher J. Mulkins, Director of Homeland Security
           Katie A. Conley, Senior Professional Staff Member
           William E. Henderson III, Minority Staff Director
              Christina N. Salazar, Minority Chief Counsel
                  Andrew J. Hopkins, Minority Counsel
          Megan M. Krynen, Minority Professional Staff Member
                     Laura W. Kilbride, Chief Clerk








































                                                      Calendar No. 654
118th Congress     }                                     {      Report
                                 SENATE
 2d Session        }                                     {     118-253

======================================================================



 
                DETECT FENTANYL AND XYLAZINE ACT OF 2024

                                _______
                                

                December 2, 2024.--Ordered to be printed

                                _______
                                

 Mr. Peters, from the Committee on Homeland Security and Governmental 
                    Affairs, submitted the following

                              R E P O R T

                         [To accompany S. 4419]

      [Including cost estimate of the Congressional Budget Office]

    The Committee on Homeland Security and Governmental 
Affairs, to which was referred the bill (S. 4419) to require 
the Science and Technology Directorate in the Department of 
Homeland Security to develop greater capacity to detect, 
identify, and disrupt illicit substances in very low 
concentrations, having considered the same, reports favorably 
thereon with an amendment, in the nature of a substitute, and 
an amendment to the title and recommends that the bill, as 
amended, do pass.

                                CONTENTS

                                                                    Page
  I. Purpose and Summary.............................................. 1
 II. Background and Need for the Legislation.......................... 2
III. Legislative History.............................................. 3
 IV. Section-by-Section Analysis of the Bill, as Reported............. 4
  V. Evaluation of Regulatory Impact.................................. 5
 VI. Congressional Budget Office Cost Estimate........................ 6
VII. Changes in Existing Law Made by the Bill, as Reported............ 6

                         I. Purpose and Summary

    S. 4419, the Detection Equipment and Technology Evaluation 
to Counter the Threat of Fentanyl and Xylazine Act of 2024, or 
the DETECT Fentanyl and Xylazine Act of 2024, amends the 
Homeland Security Act of 2002 to add to the responsibilities of 
the Under Secretary for Science and Technology (S&T) at the 
Department of Homeland Security (DHS). Specifically, the bill 
requires the Under Secretary for S&T to carry out research, 
development, testing, evaluation, and cost-benefit analyses to 
improve effectiveness and efficiency of equipment used for the 
detection of drugs, such as fentanyl and xylazine. It also 
directs the Under Secretary to carry out research, development, 
testing, evaluation, and cost-benefit analyses on the 
effectiveness and efficiency of research libraries used to 
detect drugs, such as fentanyl and xylazine. In carrying out 
these activities, the bill requires the Under Secretary for S&T 
to follow recommendations and guidelines described in the 
Artificial Intelligence Risk Management Framework. The Under 
Secretary is also directed to establish priorities for S&T's 
work based on latest available information, including specific 
drugs identified as threats by federal agencies.

              II. Background and Need for the Legislation

    According to data from the Centers for Disease Control and 
Prevention, with the exception of a slight decrease in 2023, 
drug overdose deaths in the United States have generally 
increased in recent years.\1\ Synthetic opioids, including 
fentanyl, are a leading contributor to those deaths, accounting 
for an estimated 74,000 deaths in 2023.\2\ The total number of 
Americans harmed by synthetic opioids through poisoning (e.g., 
non-fatal overdoses) is higher, though obtaining firm 
statistics is challenging due to the lack of point of care 
testing and variations in hospital use of discharge diagnosis 
codes.\3\ The fentanyl manufactured and sold by criminal 
organizations is generally found in the form of powder or made 
into pills that look like medication, such as oxycodone.\4\ In 
many cases, Americans purchasing these drugs may believe they 
are purchasing, and consuming, legitimate prescription 
medication.\5\ Because these synthetic opioids are produced in 
clandestine labs by criminal organizations, there can be 
variation in their chemical makeup and potency, making it 
difficult for law enforcement and public health agencies to 
identify substances and respond to emerging threats.\6\ For 
example, in April 2023, the Director of the Office of National 
Drug Control Policy designated fentanyl that has been combined 
with or ``occurring with'' xylazine, a veterinary tranquilizer, 
as an emerging drug threat. This designation came following 
increases in drug overdose deaths involving xylazine.\7\
---------------------------------------------------------------------------
    \1\Centers for Disease Control and Prevention, National Center for 
Health Statistics: U.S. Overdose Deaths Decrease in 2023, First Time 
Since 2018 (May 15, 2024); National Vital Statistics System 
(www.cdc.gov/nchs/nvss/vsrr/drug-overdose-data.htm) (accessed Oct. 9, 
2024).
    \2\Centers for Disease Control and Prevention, National Center for 
Health Statistics: U.S. Overdose Deaths Decrease in 2023, First Time 
Since 2018 (May 15, 2024).
    \3\Analysis of trends and usage of ICD-10-CM discharge diagnosis 
codes for poisonings by fentanyl, tramadol, and other synthetic 
narcotics in emergency department data. Addictive Behaviors Reports, 
December 2022 (Vol. 16) (www.sciencedirect.com/science/article/pii/
S2352853222000591?via%3Dihub)
    \4\Department of Justice/Drug Enforcement Administration, Drug Fact 
Sheet: Fentanyl (April 2020) (www.dea.gov/sites/default/files/2020-06/
Fentanyl-2020_0.pdf); Drug Enforcement Administration, National Drug 
Threat Assessment 2024 (DEA-DCT-DIR-010-24) (May 2024).
    \5\Drug Enforcement Administration, National Drug Threat Assessment 
2024 (DEA-DCT-DIR-010-24) (May 2024).
    \6\Drug Enforcement Administration, National Drug Threat Assessment 
2024 (DEA-DCT-DIR-010-24) (May 2024); United Nations Office on Drugs 
and Crime, World Drug Report 2024: Key Findings and Conclusions (2024) 
(www.unodc.org/documents/data-and-analysis/WDR_2024/
WDR24_Key_findings_and_conclusions.pdf).
    \7\The White House, Executive Office of the President, Office of 
National Drug Control Policy, Fentanyl Adulterated or Associated with 
Xylazine Response Plan (July 2023) (www.whitehouse.gov/wp-content/
uploads/2023/07/FENTANYL-ADULTERATED-OR-ASSOCIATED-WITH-XYLAZINE-
EMERGING-THREAT-RESPONSE-PLAN-Report-July-2023.pdf).
---------------------------------------------------------------------------
    The 2022 National Interdiction Command and Control Plan 
directed National Drug Control Program Agencies, such as DHS, 
with developing or increasing utilization of advanced 
technologies for drug detection, including to share with other 
domestic law enforcement partners.\8\ DHS S&T is led by the 
Under Secretary of Science and Technology and supports the 
operational components of the Department, such as U.S. Customs 
and Border Protection (CBP), by conducting research, 
development, testing, and evaluations. S&T also works closely 
with partners across the federal government, academia, and 
industry, and develops and tests new technologies to address 
emerging threats and capability gaps, including drug detection 
technologies.\9\ For example, CBP utilizes handheld ``chemical 
analyzers'' for preliminary results of samples taken from 
seizures suspected of being drugs.\10\
---------------------------------------------------------------------------
    \8\The White House, Executive Office of the President, Office of 
National Drug Control Policy, National Interdiction Command and Control 
Plan (2022) (www.whitehouse.gov/wp-content/uploads/2022/09/2022-
National-Interdiction-Command-and-Control-Plan-NICCP.pdf).
    \9\Department of Homeland Security, Science and Technology 
Directorate; Budget Overview Fiscal Year 2025 Congressional 
Justification (Mar. 8, 2024).
    \10\U.S. Customs and Border Protection, Frontline Digital Magazine, 
CBP: America's Frontline Against Fentanyl (www.cbp.gov/frontline/cbp-
america-s-front-line-against-fentanyl) (accessed Oct. 9, 2024).
---------------------------------------------------------------------------
    In 2023, S&T reported that low-purity drug mixtures may 
negatively impact the performance of existing technologies used 
by the components of DHS and other first responders.\11\ To 
address this challenge, S&T began working with partners, 
including the Pacific Northwest National Laboratory (PNNL), to 
evaluate existing detection technologies and better understand 
how to enhance their effectiveness. Testing performed by PNNL 
determined that multiple technologies are necessary to 
accurately determine if fentanyl is present in certain samples 
with low purity levels.\12\ The ability to make accurate 
identifications of samples help keep personnel safe, interrupt 
the supply chain of dangerous drugs like fentanyl, and support 
prosecution of those engaging in smuggling and trafficking.\13\ 
The DETECT Fentanyl and Xylazine Act of 2024 will ensure that 
S&T can continue prioritizing the improvement of drug detection 
equipment for serious public safety threats such as fentanyl 
and xylazine by adding it to the Under Secretary's 
responsibilities and authorities.
---------------------------------------------------------------------------
    \11\Department of Homeland Security, Science and Technology 
Directorate, Rapid Technologies for Drug Interdiction: Research and 
Development (July 10, 2023) (www.dhs.gov/sites/default/files/2023-08/
23_0710_s%26t_%20rapid_technologies_for_drug_interdiction_r_and_d.pdf).
    \12\Pacific Northwest National Laboratory, Performance Assessment 
of Field-Portable Instruments and Assays for Fentanyl and Fentanyl-
Related Compounds: Test Report (Sept. 2023) (www.pnnl.gov/sites/
default/files/media/file/ST_PNNL_Fentanyl_Reference_Spectra_Final_
Report_CLEARED_Public_Release.pdf).
    \13\U.S. Customs and Border Protection, Frontline Digital Magazine, 
CBP: America's Frontline Against Fentanyl (www.cbp.gov/frontline/cbp-
america-s-front-line-against-fentanyl) (accessed Oct. 9, 2024).
---------------------------------------------------------------------------

                        III. Legislative History

    Senator John Cornyn (R-TX) introduced S. 4419, the 
Detection Equipment and Technology Evaluation to Counter the 
Threat of Fentanyl and Xylazine Act of 2024, or the DETECT 
Fentanyl and Xylazine Act of 2024, on May 23, 2024, with 
original cosponsors Senator Jon Ossoff (D-GA), Senator Kyrsten 
Sinema (I-AZ), and Senator James Lankford (R-OK). The bill was 
referred to the Committee on Homeland Security and Governmental 
Affairs. Senator Jackie Rosen (D-NV) and Senator Jerry Moran 
(R-KS) later joined as cosponsors of the bill on July 23, 2024, 
and September 16, 2024, respectively.
    The Committee considered S. 4419 at a business meeting on 
September 18, 2024. During the business meeting, Senator Ossoff 
offered a substitute amendment to the bill, which made 
technical changes. It also directed the Under Secretary for S&T 
to consider specific drugs identified by DHS's most recent 
Homeland Threat Assessment when developing priorities for S&T's 
research, development, testing and evaluation. It also added a 
rule of construction to the bill stating that nothing in the 
bill can be construed to limit the authority of an agency 
currently managing, overseeing, or involved in drug equipment 
and reference libraries. The Committee adopted the Ossoff 
substitute amendment by unanimous consent with Senators Peters, 
Carper, Hassan, Sinema, Rosen, Ossoff, Blumenthal, Butler, 
Paul, Lankford, Romney, Scott, Hawley, and Marshall present.
    Senator Ossoff then offered Ossoff amendment 2, which 
changed the long title of the bill to ``A bill to require the 
Science and Technology Directorate in the Department of 
Homeland Security to develop greater capacity to detect and 
identify illicit substances in very low concentrations.'' The 
Committee adopted Ossoff amendment 2 by unanimous consent with 
Senators Peters, Carper, Hassan, Sinema, Rosen, Ossoff, 
Blumenthal, Butler, Paul, Lankford, Romney, Scott, Hawley, and 
Marshall present.
    Senator Hawley offered Hawley amendment 2, which requires 
the Director of the U.S. Secret Service to submit a report to 
Congress regarding the failed assassination attempt of Donald 
J. Trump in Butler Pennsylvania, on July 13, 2024. The 
committee adopted Hawley amendment 2 by voice vote with 
Senators Peters, Hassan, Sinema, Rosen, Ossoff, Blumenthal, 
Butler, Paul, Lankford, Romney, Scott, Hawley, and Marshall 
present.
    The bill, as amended by the Ossoff substitute amendment, 
Ossoff amendment 2, and Hawley amendment 2, was ordered 
reported favorably by a roll call vote of 13 yeas to 0 nays, 
with Senators Peters, Hassan, Sinema, Rosen, Ossoff, 
Blumenthal, Butler, Paul, Lankford, Romney, Scott, Hawley, and 
Marshall voting in the affirmative. Senators Carper and Johnson 
voted yea by proxy, for the record only.

        IV. Section-by-Section Analysis of the Bill, as Reported


Section 1. Short titles

    This section establishes the short title of the bill as the 
``Detection Equipment and Technology Evaluation to Counter the 
Threat of Fentanyl and Xylazine Act of 2024'' or the ``DETECT 
Fentanyl and Xylazine Act of 2024.''

Section 2. Enhancing the capacity to detect and identify drugs such as 
        fentanyl and xylazine

    This section amends Section 302 of the Homeland Security 
Act of 2002, which specifies the responsibilities and 
authorities of the Under Secretary for S&T. The section adds a 
paragraph directing the Secretary, through the Under Secretary 
for S&T, to carry out research, development, testing, 
evaluation, and cost-benefit analyses to improve the safety, 
effectiveness, and efficiency of equipment and the 
effectiveness and efficiency of reference libraries used for 
the accurate detection of drugs such as fentanyl and xylazine. 
It specifies that these activities, should include development 
of portable equipment that can detect and identify drugs with 
minimal or no handling of the sample. It also specifies that 
these activities include development of equipment that can 
analyze complex mixtures, such as those with varying 
concentrations of active synthetic opioids and inactive cutting 
agents, to allow field detection and identify the specific 
drug(s) present in the sample collected. Additionally, it adds 
a requirement for S&T to work on technologies that use machine 
learning or artificial intelligence and other techniques to 
predict whether the substances in a sample are controlled 
substance analogues.

Section 3. Requirements

    This section specifies requirements for the implementation 
the requirements outlined in the previous section. 
Specifically, it requires the Under Secretary for S&T to follow 
the recommendations, guidelines, and best practices described 
in the Artificial Intelligence Risk Management Framework or any 
successor document published by the National Institute of 
Standards and Technology. It also requires the Under Secretary 
to establish S&T's priorities for research, development, 
testing, evaluation, and cost-benefit analysis activities based 
on the latest available information. This includes specific 
drugs identified as threats in the latest Homeland Threat 
Assessment published by DHS and the latest State and Territory 
Report on Enduring and Emerging Threats published by the Drug 
Enforcement Administration, or any successor documents.

Section 4. Report regarding failed assassination attempt on the life of 
        Donald J. Trump

    This section requires the Director of the U.S. Secret 
Service to submit a report to appropriate congressional 
committees containing any information related to the failed 
assassination attempt on the life of Donald J. Trump on July 
13, 2024.

Section 5. Rule of construction

    This section provides a rule of construction, stating that 
nothing in the Act may be construed to limit the authority of 
agencies currently managing, overseeing, or otherwise involved 
in drug equipment and reference libraries.

                   V. Evaluation of Regulatory Impact

    Pursuant to the requirements of paragraph 11(b) of rule 
XXVI of the Standing Rules of the Senate, the Committee has 
considered the regulatory impact of this bill and determined 
that the bill will have no regulatory impact within the meaning 
of the rules. The Committee agrees with the Congressional 
Budget Office's statement that the bill contains no 
intergovernmental or private sector mandates as defined in the 
Unfunded Mandates Reform Act (UMRA) and would impose no costs 
on state, local, or tribal governments.

             VI. Congressional Budget Office Cost Estimate

    [GRAPHIC(S) NOT AVAILABLE IN TIFF FORMAT]


    S. 4419 would require the Department of Homeland Security 
(DHS) to engage in research and development of technologies and 
equipment that would help federal, state, local, tribal, and 
territorial law enforcement agencies detect illicit drug 
trafficking.
    Under current law, DHS already conducts research on 
equipment and technologies to detect and intercept illegal 
drugs. On that basis, CBO estimates that implementing S. 4419 
would cost less than $500,000 over the 2024-2029 period. Any 
related spending would be subject to the availability of 
appropriated funds.
    On July 18, 2024, CBO transmitted a cost estimate for H.R. 
8663, the DETECT Fentanyl and Xylazine Act of 2024, as ordered 
reported by the House Committee on Homeland Security on June 
12, 2024. The two pieces of legislation are similar, and CBO's 
estimates of their budgetary effects are the same.
    The CBO staff contact for this estimate is Jeremy Crimm. 
The estimate was reviewed by H. Samuel Papenfuss, Deputy 
Director of Budget Analysis.
                                         Phillip L. Swagel,
                             Director, Congressional Budget Office.

       VII. Changes in Existing Law Made by the Bill, as Reported

    In compliance with paragraph 12 of rule XXVI of the 
Standing Rules of the Senate, changes in existing law made by 
the bill, as reported, are shown as follows: (existing law 
proposed to be omitted is enclosed in brackets, new matter is 
printed in italic, and existing law in which no change is 
proposed is shown in roman):

HOMELAND SECURITY ACT OF 2002

           *       *       *       *       *       *       *


TITLE III--SCIENCE AND TECHNOLOGY IN SUPPORT OF HOMELAND SECURITY

           *       *       *       *       *       *       *


SEC. 302. RESPONSIBILITIES AND AUTHORITIES OF THE UNDER SECRETARY FOR 
                    SCIENCE AND TECHNOLOGY.

           *       *       *       *       *       *       *


          (13) coordinating with other appropriate executive 
        agencies in developing and carrying out the science and 
        technology agenda of the Department to reduce 
        duplication and identify unmet needs; [and]
          (14) developing and overseeing the administration of 
        guidelines for merit review of research and development 
        projects throughout the Department, and for the 
        dissemination of research conducted or sponsored by the 
        Department[.]; and
          (15) carrying out research, development, testing, 
        evaluation, and cost-benefit analyses to improve the 
        safety, effectiveness, and efficiency of equipment and 
        the effectiveness and efficiency of reference libraries 
        for use by Federal, State, local, Tribal, and 
        territorial law enforcement agencies for the accurate 
        detection of drugs, such as fentanyl and xylazine, 
        including----
                  (A) portable equipment that can detect and 
                identify drugs with minimal or no handling of 
                the sample;
                  (B) equipment that can separate complex 
                mixtures containing low concentrations of drugs 
                and high concentrations of cutting agents into 
                their component parts to enable signature 
                extraction for field identification and 
                detection; and
                  (C) technologies that use machine learning or 
                artificial intelligence (as defined in section 
                5002 of the National Artificial Intelligence 
                Initiative Act of 2020 (15 U.S.C. 9401)) and 
                other techniques to predict whether the 
                substances in a sample are controlled substance 
                analogues or other new psychoactive substances 
                not yet included in available reference 
                libraries.

           *       *       *       *       *       *       *


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