[Congressional Record Volume 172, Number 113 (Monday, July 13, 2026)]
[Senate]
[Pages S3900-S3903]
From the Congressional Record Online through the Government Publishing Office [www.gpo.gov]

  SA 6666. Mr. YOUNG (for himself, Mr. Padilla, Mr. Cotton, Ms. 
Klobuchar, Mr. Fetterman, and Mr. Budd) submitted an amendment intended 
to be proposed by him to the bill S. 4784, to authorize appropriations 
for fiscal year 2027 for military activities of the Department of 
Defense, for military construction, and for defense activities of the 
Department of Energy, to prescribe military personnel strengths for 
such fiscal year, and for other purposes; which was ordered to lie on 
the table; as follows:

        At the end, add the following:

         DIVISION F--AMERICAN BIOTECHNOLOGY COMPETITIVENESS ACT

     SECTION 1. SHORT TITLE.

       This division may be cited as the ``American Biotechnology 
     Competitiveness Act''.

           TITLE I--BIOSECURITY MODERNIZATION AND INNOVATION

     SEC. 101. DEFINITIONS.

       In this division:
       (1) Benchtop nucleic acid synthesizer.--The term ``benchtop 
     nucleic acid synthesizer'' means a device or integrated 
     system that--
       (A)(i) is capable of performing de novo synthesis of 
     nucleic acid sequences by an end user at the site of use; or
       (ii) is capable of performing de novo synthesis of nucleic 
     acid sequences without requiring the end user to submit an 
     order to a separate covered entity to perform such synthesis; 
     and
       (B) is intended for distribution to, or use by, individual 
     researchers, research institutions, institutional core 
     facilities, or other end users, regardless of the physical 
     dimensions of such device or system.
       (2) Covered entity.--
       (A) In general.--Except as provided in subparagraph (B), 
     the term ``covered entity'' means a person who--
       (i) synthesizes and sells synthetic nucleic acids to 
     persons in the United States or in a foreign country; or
       (ii) produces and distributes or sells, including 
     resellers, equipment for synthesizing nucleic acids, 
     including benchtop nucleic acid synthesizers, to persons in 
     the United States or in a foreign country.
       (B) Exception.--The term ``covered entity'' does not 
     include a person to the extent the person sells or 
     distributes synthetic nucleic acids within a commercial 
     entity for the purpose of such entity's research and 
     development activities.
       (3) Director.--The term ``Director'' means the Director of 
     the Office of Science and Technology Policy.
       (4) Secretary.--The term ``Secretary'' means the Secretary 
     of Commerce.
       (5) Under secretary.--The term ``Under Secretary'' means 
     the Under Secretary of Commerce for Standards and Technology.

     SEC. 102. SENSE OF CONGRESS.

       It is the Sense of Congress that--
       (1) the field of biotechnology is accelerating and the 
     United States is at risk of losing its biotechnology 
     leadership to foreign adversaries;
       (2) this acceleration of the field brings the United States 
     into a period of both great opportunity and risk;
       (3) policymaking for biosecurity, biosafety, and 
     responsible innovation needs to be flexible to keep pace with 
     advances in the biotechnology and ensure an environment that 
     allows biotechnology research and industry to flourish;
       (4) the current landscape of biosecurity and biosafety 
     authorities is spread among multiple agencies, contributing 
     to slow policymaking, which, coupled with the rapid 
     advancement of biotechnology, becomes outdated quickly;
       (5) previous studies conducted by the Government 
     Accountability Office, the National Security Commission for 
     Emerging Biotechnology, and several presidential 
     administrations have already identified gaps in the Federal 
     Government's oversight of biosecurity and biosafety risks;
       (6) the United States Government needs to streamline 
     biosecurity and biosafety authorities to ensure efficiency 
     and clarity;
       (7) gene synthesis technology is becoming increasingly 
     sophisticated and accessible, along with the ability to 
     design novel nucleic acid sequences;
       (8) both of these factors described in paragraph (7) may 
     increase the risk of the development and deployment of new 
     pathogens by bad actors; and
       (9) gene synthesis screening of orders and customers is 
     immediately needed to mitigate risk in the short-term, which 
     will act as a stopgap while the United States Government 
     develops a comprehensive biosecurity and biosafety strategy 
     that is appropriate for the dynamic and rapidly advancing 
     field of biotechnology.

     SEC. 103. NUCLEIC ACID SYNTHESIS SECURITY.

       (a) Regulations Required.--
       (1) In general.--Not later than 1 year after the date of 
     the enactment of this Act, the Secretary shall, in 
     consultation with the heads of other agencies as the 
     Secretary considers appropriate, establish and maintain by 
     regulation the following:
       (A) A requirement for covered entities to implement 
     screening protocols to detect sequence inputs, synthesis 
     instructions, and orders for sequences of concern included in 
     the list established and maintained under subparagraph (C), 
     including sequences generated through benchtop nucleic acid 
     synthesizers. Such protocols shall--
       (i) include the ability for privacy-preserving submission 
     of information regarding sequence inputs, synthesis 
     instructions, and orders for potential sequences of concern 
     to a mechanism, which may be maintained by the Secretary or 
     an independent organization designated by the Secretary, for 
     facilitating effective split order detection across covered 
     entities, utilizing the list established and maintained under 
     subparagraph (C); and
       (ii) prioritize the mitigation of misuse of sequences 
     capable of creating pathogens with pandemic potential.
       (B) A requirement for covered entities to implement 
     screening protocols to verify the identity and legitimacy of 
     customers.
       (C) A list of sequences of concern, which shall be 
     determined by the Secretary in consultation with the heads of 
     Federal departments and agencies as the Secretary considers 
     appropriate.
       (D) A system for reviewing and updating on a regular basis 
     the list of sequences of concern established and maintained 
     under subparagraph (C) that--
       (i) uses a docket to allow for privacy-preserving 
     submissions from the public on recommendations for the list 
     of sequences of concern;
       (ii) includes an expedited procedure to rapidly add 
     sequences of concern to the list on a provisional basis, 
     which may include, as far as technically feasible, automatic 
     procedures such as algorithmic literature scanning, industry 
     self-reporting, or inter-agency submissions; and
       (iii) incorporates strong data security and confidentiality 
     standards.
       (E) A conformity assessment system to verify that covered 
     entities are adhering to the requirements established and 
     maintained under subparagraphs (A) and (B), which will 
     include--
       (i) an auditing process to ensure sequence inputs, 
     synthesis instructions, orders, and customers have been 
     scrutinized appropriately, including procedures to conduct 
     adversarial testing (sometimes referred to as ``red-
     teaming'') in accordance with the standards developed under 
     subsection (c)(4), at random intervals to ensure compliance; 
     and
       (ii) a process to revoke conformity status of covered 
     entities that fail to maintain compliance with the 
     requirements established and maintained under subparagraphs 
     (A) and (B), including the establishment of a grace period 
     for covered entities who have failed auditing or adversarial 
     testing under clause (i) to demonstrate compliance or 
     mitigation steps.
       (F) A process, administered by an official of the 
     Department of Commerce designated by the Secretary--
       (i) to receive findings from testing conducted in 
     accordance with the standards developed under subsection 
     (c)(4), reports of suspicious orders submitted by covered 
     entities, and related tips and referrals from Federal, State, 
     or local authorities;
       (ii) to determine whether a reported order corresponds to a 
     test order submitted in accordance with the standards 
     developed under subsection (c)(4) and, if so, record the 
     covered entity's identification of the order as evidence of 
     compliance and close the report without referral to any law 
     enforcement agency; and
       (iii) to act on a valid finding that a covered entity has 
     failed to maintain compliance with a requirement under this 
     paragraph, including by affording the covered entity notice 
     and a grace period as established in subparagraph (E)(ii).
       (G) Safeguards to ensure regulations promulgated under this 
     subsection avoid unnecessary burden on innovation and 
     industry by--
       (i) allowing covered entities to offer an expedited review 
     process for institutional customers, including considering 
     principal investigators at institutions of higher education, 
     with demonstrated records of legitimacy;
       (ii) providing exemptions from customer screening 
     requirements for sequences or products as determined in 
     clause (iii) that are clearly non-hazardous and pose no 
     credible threat to public health or national security based 
     on scientific literature and industry best practices for 
     biosecurity screening; and
       (iii) conducting regular consultations with relevant 
     experts to determine exempted sequences and minimize 
     regulatory burden while maintaining security effectiveness.
       (2) Rules of construction.--Paragraph (1)(A) shall not be 
     construed--
       (A) to prohibit a covered entity, as defined in section 
     101(2)(A)(i), from synthesizing a sequence; or

[[Page S3901]]

       (B) to prohibit a covered entity, as defined in section 
     101(2)(A)(ii), from producing equipment for synthesizing 
     nucleic acids.
       (b) Program of Technical Assistance.--
       (1) Program required.--The Secretary shall establish a 
     program to provide technical assistance upon request of a 
     covered entity, including assistance with orders whose 
     screening results are ambiguous, subject to determination by 
     the Secretary, in consultation with the heads of such other 
     Federal departments and agencies as the Secretary considers 
     appropriate.
       (2) Treatment of information received.--Information 
     received as part of the technical assistance request under 
     paragraph (1) may not be used in any enforcement against a 
     covered entity.
       (c) National Institute of Standards and Technology 
     Requirements.--Not later than 1 year after the date of the 
     enactment of this Act, the Under Secretary shall develop best 
     practices, technical standards, and other tools needed to 
     support the administration of subsection (a), including the 
     following:
       (1) Testing and evaluation of customer and order screening 
     protocols to improve accuracy, efficacy, and reliability, and 
     to support the conformity assessment system under subsection 
     (a)(1)(E).
       (2) Evaluation of the sequences recommended for the list 
     established and updated under subparagraphs (C) and (D) of 
     subsection (a)(1), including by developing best practices and 
     guidelines for determining if a novel sequence is a sequence 
     of concern.
       (3) Research and prototype sequence-to-function models to 
     supplement the system established and maintained under 
     subsection (a)(1)(D).
       (4) Standards for the independent testing of the screening 
     of sequence inputs, synthesis instructions, orders, and 
     customers by covered entities (sometimes referred to as 
     ``red-teaming''), which shall include--
       (A) a testing protocol, consisting of test sequences, 
     simulated customer profiles, and order patterns, that is 
     designed so that test orders are not readily distinguishable 
     from legitimate orders, is reviewed and updated not less 
     frequently than once each year, and is not disclosed to 
     covered entities or to the public;
       (B) criteria for a qualified testing entity, including 
     that--
       (i) such entity has no financial interest in a market 
     competitor of the covered entity being tested, and the 
     routine procurement of nucleic acid synthesis products, or 
     the receipt of membership dues by a nonprofit or academic 
     entity shall not constitute such an interest; and
       (ii) such entity maintains controls adequate to safeguard 
     testing protocols and entity-specific results; and
       (C) criteria for a valid finding, requiring documented 
     evidence that a test order was submitted to a covered entity 
     by a qualified testing entity in accordance with the 
     standards developed under this paragraph and that the covered 
     entity acted inconsistently with a requirement under 
     paragraph (1) or (2).
       (5) For covered entities, as specified in section 
     101(2)(A)(ii), technical standards and cybersecurity 
     specifications for securing benchtop nucleic acid 
     synthesizers as feasible and appropriate.
       (d) Updates.--As frequently as the Secretary considers 
     appropriate to account for technological advances, but not 
     less frequently than once every 2 years, the Secretary shall 
     review and update the regulations promulgated under 
     subsection (a).
       (e) Protection of Customer Information.--Any information 
     about a customer included in a submission under subparagraph 
     (A)(i) or (D)(i) of subsection (a)(1) shall, be kept 
     confidential and shall be exempt from disclosure under 
     section 552(b)(3) of title 5, United States Code.
       (f) Relationship With Other Federal Guidelines and 
     Recommendations.--The regulations established and maintained 
     under subparagraphs (A) and (B) of subsection (a)(1) shall 
     supplant any Federal guidelines or recommendations relating 
     to nucleic acid synthesis screening that--
       (1) were in effect before the date of the enactment of this 
     Act; and
       (2) are voluntary.
       (g) Civil Enforcement.--
       (1) Civil action.--The Attorney General may bring a civil 
     action in a court of competent jurisdiction against any 
     person who violates a requirement promulgated under 
     subparagraph (A) or (B) of subsection (a)(1), including 
     through providing false or misleading information or engaging 
     in other deceptive practices, or does not demonstrate 
     compliance within the grace period set forth by subsection 
     (a)(1)(E)(ii).
       (2) Powers of the court.--In an action brought under 
     paragraph (1), the court may--
       (A) enjoin a violation described in paragraph (1); and
       (B) award damages under paragraph (3).
       (3) Award of damages.--A person who violates a requirement 
     as described in paragraph (1) is liable for statutory 
     damages--
       (A) in the case of an individual, in the sum of not more 
     than $500,000, adjusted from time to time under paragraph 
     (4); and
       (B) in the case of a person who is not an individual, in 
     the sum of not more than $750,000, adjusted from time to time 
     under paragraph (4).
       (4) Adjustments for inflation.--Effective on October 1 of 
     each year (beginning in the first fiscal year after the date 
     of the enactment of this Act), the dollar amounts in effect 
     under paragraph (3) shall be increased by a percentage equal 
     to the percentage by which the Consumer Price Index for all 
     urban consumers (U.S. city average) increased during the 12-
     month period ending with the last month for which Consumer 
     Price Index data is available. In the event that such 
     Consumer Price Index does not increase during such period, 
     the dollar amount in effect under such paragraph during the 
     previous fiscal year shall be maintained.
       (h) Safe Harbor for Qualified Testing.--
       (1) In general.--A qualified testing entity, and any 
     individual acting on behalf of such entity, that conducts 
     testing in good faith and in accordance with the standards 
     developed under subsection (c)(4) shall not, for any act 
     reasonably necessary, including use of a simulated identity, 
     submission of a test order or associated procurement, or 
     shipping activity to carry out such testing--
       (A) be liable for breach of contract or of a covered 
     entity's terms of service; or
       (B) be treated as having violated a provision of Federal or 
     State law solely by reason of the use of a simulated identity 
     or the provision of false or simulated information reasonably 
     necessary to carry out such testing under subsection (c)(4).
       (2) Exceptions.--The safe harbor in paragraph (1) shall not 
     apply to an entity or individual that conducts testing--
       (A) for the primary purpose of obtaining a competitive 
     advantage;
       (B) that intentionally disrupts the commercial or 
     laboratory operations of a covered entity;
       (C) that submits a finding the entity or individual knows 
     to be false or materially incomplete;
       (D) that publicly discloses a specific vulnerability of an 
     identified covered entity before the end of a remediation 
     period established by the Secretary; or
       (E) for the primary purpose of inflicting harm upon the 
     United States bioeconomy or national security, including 
     actions taken at the direction of a foreign adversary.
       (i) Reports to Congress.--Not less frequently than once 
     each year, the Secretary shall submit to Congress a report on 
     the administration of this section. Each such report shall 
     include an overview of how many covered entities have been 
     verified by the conformity assessment system established and 
     maintained under subsection (a)(1)(E).

     SEC. 104. ESTABLISHMENT OF BIOTECHNOLOGY GOVERNANCE TESTING 
                   PROGRAM.

       (a) In General.--Not later than 1 year after the date of 
     the enactment of this Act, the Under Secretary shall, in 
     collaboration with the heads of such Federal agencies as the 
     Under Secretary considers relevant and with such persons in 
     the private sector, academia, and civil society as the Under 
     Secretary considers appropriate, establish a biotechnology 
     governance testing program.
       (b) Responsibilities.--Under the program established under 
     subsection (a), the Under Secretary shall--
       (1) provide secure testing of innovations or tools 
     developed to advance the science of biosecurity, biosafety, 
     and responsible biotechnology innovation;
       (2) foster participation of nongovernmental experts in the 
     development and testing of appropriate levels and methods of 
     governance, to achieve the goals of--
       (A) ensuring the continued global competitiveness of 
     biotechnology innovations in the United States; and
       (B) strengthening the ability of the United States to 
     robustly analyze emerging threats, anticipate concerns, and 
     govern proactively in the biotechnology space;
       (3) carry out biological measurement research to support 
     the development and improvement of technical standards for 
     biosecurity, biosafety, and responsible biotechnology 
     innovation; and
       (4) report annually to the Secretary of Commerce on the 
     administration of paragraph (2) and whether any promising 
     governance strategies have resulted from the development and 
     testing.
       (c) Access to Environments.--The Under Secretary may 
     contract with the private sector or coordinate with other 
     Federal agencies to access environments necessary to provide 
     testing under subsection (b)(1).

     SEC. 105. STREAMLINING BIOSECURITY AND BIOSAFETY AUTHORITIES 
                   ACROSS THE FEDERAL GOVERNMENT.

       (a) Assessment and Plan Required.--Not later than 90 days 
     after the date of the enactment of this Act, the Director 
     shall, in collaboration with the heads of such Federal 
     agencies as the Director considers relevant--
       (1) assess the current state of biosecurity and biosafety 
     oversight by the Federal Government; and
       (2) develop, based on the findings of the Director with 
     respect to the assessment conducted under paragraph (1), an 
     implementation plan to make oversight of biosecurity and 
     biosafety by the Federal Government more effective and 
     efficient.
       (b) Elements of Assessment.--The assessment required by 
     subsection (a)(1) shall include the following:
       (1) A full accounting of Federal biosecurity and biosafety 
     authorities and programs, including which agencies hold these 
     authorities, whether these authorities are exercised 
     effectively, and where there are overlaps or redundancies, 
     real or perceived, in regulatory and enforcement authorities.
       (2) Engagement with industry stakeholders and academia to 
     understand where there are challenges with compliance, 
     communication, and information sharing.
       (3) Identification of gaps in funding or other Government 
     support for the development of research, innovation, and 
     tools that

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     advance the science of applied biosecurity, biosafety, and 
     responsible biotechnology innovation.
       (4) Identification of gaps in current Federal biosecurity 
     and biosafety authorities and whether these gaps are 
     hindering effective and efficient governance and assessment 
     of emerging risks and opportunities in biotechnology.
       (5) An evaluation of how consolidation of biosecurity and 
     biosafety guidelines, authorities, and regulations across 
     Federal agencies, including the regulations established and 
     maintained under section 103(a), should be implemented to 
     make oversight more effective and efficient and to address 
     the gaps in such guidelines, authorities, and regulations, 
     including those identified under paragraphs (3) and (4).
       (c) Report to Congress.--
       (1) In general.--Not later than 90 days after the date on 
     which the Director completes the assessment required by 
     paragraph (1) of subsection (a) and the implementation plan 
     required by paragraph (2) of such subsection, the Director 
     shall submit to Congress--
       (A) a report on the findings of the Director with respect 
     to the assessment; and
       (B) a copy of the implementation plan.
       (2) Contents.--The report submitted pursuant to paragraph 
     (1)(A) shall include the following:
       (A) The findings of the Director with respect to the 
     assessment conducted pursuant to subsection (a)(1), with an 
     annex for classified and business confidential information, 
     as needed.
       (B) Recommendations for legislative or administrative 
     action to support the implementation plan developed under 
     subsection (a)(2), according to--
       (i) what, if any, new biosecurity and biosafety authorities 
     are needed; and
       (ii) where the Federal Government can consolidate 
     biosecurity and biosafety authorities, including which, if 
     any, should be reside under a common government entity, and 
     whether this necessitates establishing a new government 
     entity.
       (d) Implementation.--
       (1) In general.--Not later than 90 days after the date on 
     which the Director completes the implementation plan required 
     by subsection (a)(2), the Director shall commence 
     implementing the plan through administrative action in 
     accordance with applicable provisions of law.
       (2) Governance strategies.--In carrying out the 
     implementation plan developed under subsection (a)(2), the 
     Director shall consider which, if any, of the governance 
     strategies reported under section 104(b)(4) should be 
     included in the plan.

       TITLE II--NATIONAL PROGRAMMABLE CLOUD LABORATORIES NETWORK

     SEC. 201. DEFINITIONS.

       (a) Definitions.--In this title:
       (1) Artificial intelligence.--The term ``artificial 
     intelligence'' has the meaning given that term in section 
     5002 of the William M. (Mac) Thornberry National Defense 
     Authorization Act for Fiscal Year 2021 (15 U.S.C. 9401).
       (2) Biological data.--The term ``biological data'' means 
     the information, including associated descriptors, derived 
     from the structure, function, or process of a biological 
     system that is either measured, collected, or aggregated for 
     analysis.
       (3) Director.--Unless otherwise provided, the term 
     ``Director'' means the Director of the National Science 
     Foundation.
       (4) Institution of higher education.--The term 
     ``institution of higher education'' has the meaning given 
     that term in section 101 of the Higher Education Act of 1965 
     (20 U.S.C. 1001).
       (5) Network.--The term ``Network'' means the National 
     Programmable Cloud Laboratories Network.
       (6) Node.--The term ``node'' means a programmable cloud 
     laboratory designated as part of the Network.
       (7) Non-designated laboratory.--The term ``non-designated 
     laboratory'' means any Federal, academic, nonprofit, or 
     private industry programmable cloud laboratory not selected 
     as a node under section 203.
       (8) Programmable cloud laboratory.--The term ``programmable 
     cloud laboratory'' means a physical laboratory that is 
     equipped with research instrumentation and advanced 
     manufacturing capabilities, including robotics and artificial 
     intelligence, that can be securely and remotely programmed 
     and controlled in order to conduct experiments and collect 
     associated data.

     SEC. 202. AUTHORIZATION OF APPROPRIATIONS.

       There are authorized to be appropriated to carry out the 
     activities under this title--
       (1) $30,000,000 for fiscal year 2026;
       (2) $30,000,000 for fiscal year 2027;
       (3) $30,000,000 for fiscal year 2028;
       (4) $30,000,000 for fiscal year 2029; and
       (5) $30,000,000 for fiscal year 2030.

     SEC. 203. NATIONAL PROGRAMMABLE CLOUD LABORATORIES NETWORK.

       (a) Purposes.--The purposes of the Network established 
     under this title are--
       (1) to maintain leadership by the United States in advanced 
     experimentation, laboratory automation, and artificial 
     intelligence for scientific research, advanced manufacturing, 
     long-term economic competitiveness, and national security;
       (2) to reduce the cost of federally funded research through 
     automation and reproducibility;
       (3) to accelerate national competitiveness by transferring 
     government-funded research to private-sector commercial 
     applications;
       (4) to improve collaboration among federally funded 
     national laboratories, institutions of higher education, and 
     private industry;
       (5) to ensure that investment in programmable cloud 
     laboratories results in measurable cost savings, 
     efficiencies, and long-term fiscal sustainability;
       (6) to incentivize private-sector cost-sharing in research 
     infrastructure and equipment;
       (7) to support workforce development aligned with the 
     technical needs of industry in the United States;
       (8) to provide funding for nodes;
       (9) to advance the development of a domestic industrial 
     base for scientific automation tools, artificial intelligence 
     systems for experimentation, and robotics platforms for use 
     in laboratory settings; and
       (10) to further programmable cloud laboratory research in 
     areas such as materials science, biotechnology, chemistry, 
     and other scientific or engineering disciplines where 
     automation and cloud-enabled experimentation can deliver 
     transformative results, including advanced materials 
     synthesis and characterization, scalable biotechnology 
     experimentation, and high-throughput chemical catalyst 
     development.
       (b) Establishment.--
       (1) In general.--
       (A) Establishment.--Not later than 1 year after the date of 
     the enactment of this Act, the Director, in consultation with 
     the Director of the National Institute of Standards and 
     Technology, shall designate and oversee a National 
     Programmable Cloud Laboratories Network of not more than 6 
     nodes to support secure, standards-based, and cost-effective 
     remote experimentation and automated research.
       (B) Awards.--The Director shall award a grant to each node, 
     in an amount not to exceed $5,000,000 per fiscal year for a 
     period of not more than 5 years, to support the Network.
       (2) Assessment sequencing.--The assessment required under 
     section 304 shall be conducted only after the final 
     designation of nodes under paragraph (1).
       (3) Nodes.--The Network shall consist of nodes that--
       (A) enable programmable workflows and automated science;
       (B) provide access to advanced scientific and manufacturing 
     instruments, including artificial intelligence-enabled tools;
       (C) collaborate to establish and adopt common standards, 
     protocols, and best practices; and
       (D) support interoperability across and between nodes.
       (c) Application and Selection.--
       (1) In general.--The Director shall issue a public 
     solicitation for eligible entities to apply for node 
     designation.
       (2) Eligible entities.--Eligible entities that may apply 
     for designation as a node include--
       (A) institutions of higher education;
       (B) nonprofit research organizations;
       (C) private-sector research entities; and
       (D) consortia or collaborations of the entities described 
     in subparagraphs (A) through (C).
       (d) Applications for Designation.--
       (1) In general.--An eligible entity that desires to apply 
     for designation as a node in the Network shall submit an 
     application to the Director at such time and in such manner 
     as the Director may require.
       (2) Matters to be included.--The application required under 
     paragraph (1) shall include--
       (A) a technical and programmatic plan for laboratory 
     operations, automation capabilities, and data integration;
       (B) a plan to achieve long-term self-sustainability, 
     including metrics, interim milestones, and a timeline for 
     reducing reliance on Federal funding; and
       (C) evidence of non-Federal cost share, private capital, or 
     other third-party contributions demonstrating self-
     sustainability potential.
       (e) Evaluation of Applicants.--The Director shall ensure 
     that the process for selecting eligible entities for 
     designation in the Network is competitive, merit-based, and 
     transparent, through the evaluation of, with respect to each 
     entity--
       (1) pre-existing laboratory infrastructure and suitability 
     for automated science;
       (2) capacity to support distributed, cloud-enabled 
     programmable workflows for multiple users;
       (3) likelihood of achieving long-term sustainability 
     without continued Federal funding;
       (4) demonstrated ability to collaborate with other nodes, 
     academic partners, industry partners, or other Federal 
     research agencies (as defined in section 10002 of the 
     Research and Development, Competition, and Innovation Act (42 
     U.S.C. 18901));
       (5) protocols for research security, cybersecurity, and 
     responsible access; and
       (6) demonstration of user interest and research needs.
       (f) Designation.--In designating nodes, the Director 
     shall--
       (1) give preference to applicants demonstrating meaningful 
     third-party cost share and pre-existing infrastructure; and
       (2) to the extent practicable, ensure that at least 1 node 
     demonstrates the capability to support cloud-enabled 
     biotechnology research, including automated experimentation 
     or quality control workflows.
       (g) Responsibilities.--Each node selected by the Director 
     shall--

[[Page S3903]]

       (1) support the purposes described in subsection (a);
       (2) facilitate collaboration among Network members to 
     expand and integrate automated science capabilities and best 
     practices;
       (3) actively participate with the Director of National 
     Institute of Standards and Technology in developing network-
     wide interoperability, data-sharing, cybersecurity, and 
     artificial intelligence-assisted experimentation standards;
       (4) support secure sharing of experimental data, models, 
     and results across institutions of higher education 
     participating in the Network, if applicable;
       (5) provide a secure digital infrastructure to enable 
     remote experimentation, artificial intelligence-assisted 
     analysis, and reproducible science;
       (6) engage in public-private partnerships to streamline the 
     transfer of technology developed using Network 
     infrastructure;
       (7) develop and maintain a financial sustainability plan to 
     reduce long-term reliance on Federal funds, including through 
     user fees, licensing, consortia membership, or other revenue-
     generating models;
       (8) establish performance metrics, including scientific 
     output, cost-effectiveness, academic engagement, private-
     sector engagement, user satisfaction, and reproducibility of 
     results; and
       (9) where practicable, leverage commercially available 
     hardware and software solutions to minimize cost and 
     accelerate deployment of automated science capabilities.

     SEC. 204. INTERAGENCY COLLABORATION.

       Not later than 180 days after all nodes of the Network are 
     designated, the Director of the National Institute of 
     Standards and Technology, in cooperation with the Director 
     and participating eligible entities (including institutions 
     of higher education), shall--
       (1) develop and promulgate standards to ensure 
     interoperability across Network nodes, including laboratory 
     instrumentation, data infrastructure, communication 
     protocols, and experiment execution systems;
       (2) establish protocols for secure, seamless, and 
     standardized data-sharing among all members of the Network 
     aligned with node-level cybersecurity and research security 
     protocols;
       (3) define minimum technical requirements and operating 
     procedures to support remote experimentation, experiment 
     reproducibility, and artificial intelligence-assisted 
     workflows; and
       (4) periodically update such standards in consultation with 
     private-sector partners and nodes of the Network to reflect 
     advancements in hardware, software, and automation 
     technology.

     SEC. 205. ASSESSMENT OF NON-DESIGNATED LABORATORIES.

       (a) Assessment Requirement.--Not later than 180 days after 
     the Director designates the final node of the Network under 
     section 203, the Director, in consultation with the Secretary 
     of Energy and the Director of the National Institute of 
     Standards and Technology, shall conduct and submit to the 
     appropriate committees of Congress, a comprehensive 
     assessment of non-designated laboratories.
       (b) Scope.--The assessment under subsection (a) shall 
     identify, to the extent practicable--
       (1) Federal laboratories, institutions of higher education, 
     nonprofit organizations, and private-sector laboratories that 
     possess or are developing programmable, automated, or 
     remotely accessible research infrastructure;
       (2) the instrumentation, automation, and data capabilities 
     of such laboratories;
       (3) cybersecurity and research security measures relevant 
     to interoperability;
       (4) existing or potential pathways for such laboratories to 
     coordinate with Network nodes in areas such as data-sharing, 
     standards adoption, or pilot interoperability projects; and
       (5) legal, contractual, or intellectual property 
     considerations that may affect participation in the Network.
       (c) Confidentiality and Security.--
       (1) In general.--In carrying out the assessment under 
     subsection (a), the Director shall ensure that proprietary 
     information is protected from public disclosure consistent 
     with applicable law.
       (2) Publication of nonproprietary public summary.--The 
     Director shall publish a nonproprietary public summary of the 
     assessment under subsection (a) and may submit a proprietary 
     annex for that assessment to the Committee on Commerce, 
     Science, and Transportation of the Senate and the Committee 
     on Science, Space, and Technology of the House of 
     Representatives.

     SEC. 206. REPORTING AND OVERSIGHT.

       (a) Annual Briefings.--Not later than 1 year after the date 
     of the enactment of this Act, and annually thereafter, the 
     Director shall brief the Committee on Commerce, Science, and 
     Transportation of the Senate and the Committee on Science, 
     Space, and Technology of the House of Representatives on the 
     status of the Network.
       (b) Contents.--Each briefing required under subsection (a) 
     shall include an assessment of--
       (1) the alignment of supported research with national 
     scientific and economic priorities;
       (2) the progress each node of the Network has made toward 
     achieving self-sustainability as described in section 
     203(d)(2)(B); and
       (3) the performance metrics established in section 
     203(g)(8).

     SEC. 207. SUNSET.

       The National Programmable Cloud Laboratories Network, 
     including all authorities, programs, and funding provided 
     under this title, shall terminate on September 30, 2031.
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