[Congressional Record Volume 160, Number 69 (Thursday, May 8, 2014)]
[House]
[Pages H4009-H4014]
From the Congressional Record Online through the Government Publishing Office [www.gpo.gov]
CANCER RESEARCH
The SPEAKER pro tempore. Under the Speaker's announced policy of
January 3, 2013, the gentleman from New Jersey (Mr. Lance) is
recognized for 60 minutes as the designee of the majority leader.
Mr. LANCE. Mr. Speaker, tonight, my colleagues and I rise to discuss
a matter that has touched virtually every family America and is one of
the great public health challenges of our time--or indeed, of any
time--and that is the challenge of cancer, the diagnosis no person
wants to hear and the battle no one should face alone.
From those in treatment to those working toward prevention to friends
and family dealing with the terrible illness of a loved one, everyone
knows someone who has been afflicted with cancer. Cancer has been the
great health menace of the last century.
But now, here in the 21st century, medical advancement, innovative
treatments, and the genius of many scientists and medical doctors are
everyday bringing us closer to a cure.
We await the advent of new technologies and of work here in Congress
to deliver the tools and resources both to public and to private
industry to spur the research and collaborations that will change the
health of the world.
It is my judgment that the United States is really the medical center
of the entire world and that its brilliant medical doctors and
scientists here in this country will lead the charge in the new
century.
Clinical oncologists are on the cutting edge of that research and are
responsible for many of the advances in cancer care that are improving
the lives and prognoses for many cancer patients.
This year marks the 50th anniversary of the American Society of
Clinical Oncology, a group which represents nearly 35,000 oncology
professionals across the world.
When ASCO was founded in 1964, it dedicated itself to a challenging
mission: a commitment to conquer cancer through research, education,
prevention, and the delivery of high-quality patient care.
When ASCO was founded, cancer was widely regarded as an untreatable
disease, with fewer than one-half of patients alive 5 years after
diagnosis. There was an undeniable stigma associated with a cancer
diagnosis that left many patients to suffer in silence, with minimal
support, and worse, few effective therapies.
But because of the work of passionate advocates and tireless
champions, the expertise of talented medical professionals, including
those at the American Society of Clinical Oncology, today the survival
rate is higher than two-thirds.
Better cancer prevention and detection, improved care coordination,
and the use of palliative care have proven to improve patients' quality
of life dramatically and to increase survival rates dramatically.
ASCO has put forward new technologies such as nanotechnology, medical
imaging, and health information technology that are leading to entirely
new ways to develop therapies. If these advances are fully realized,
people with cancer will be able to receive more personalized and more
effective treatment.
In my work on the Energy and Commerce Committee, and particularly on
its Health Subcommittee, I am sure that the wave of the future is
personalized medical care. In a coordinated capacity, the members of
the committee, and particularly of the subcommittee, are working
together to create that new wave of the future regarding personalized
medicine.
Federal investments in cancer research have also resulted in a
massive increase in the number and the quality of treatments available
to cancer patients.
I have the highest confidence in Dr. Francis Collins and his team at
the National Institutes of Health. I have toured NIH's magnificent
facility in Bethesda, the best of its kind on the face of the Earth. I
can report that some of the best doctors, the greatest intellects, and
dedicated professionals are working every day to course the future of
medicine and tackle this terrible disease.
We must continue our Nation's commitment to NIH to keep the United
States as the global center of medical innovation.
Yesterday, Mr. Speaker, the chairman of the Energy and Commerce
Committee, Mr. Upton of Michigan, convened a roundtable with many of
the most brilliant doctors regarding issues affecting the NIH. We were
privileged that Dr. Collins joined us.
But the work will not be done alone by public entities such as the
Federal Government and NIH. In fact, great minds from across this
Nation and around the world have brought their desire to rid the world
of cancer to some of the finest companies on the forefront of this
research.
I am honored to say that many of these life science leaders in the
medical and biopharmaceutical research and development field call the
district I serve and the State I serve, New Jersey, home. There is work
on cancer solutions every day in labs I have the honor of representing.
[[Page H4010]]
The district I serve, Mr. Speaker, has more pharmaceutical and
medical device employees than any other district in the United States.
But that is not to say we are alone. There are magnificent facilities
across this country. They will be described, I believe, by colleagues
of mine this evening.
I know there is great interest and commitment in the House of
Representatives, as demonstrated by the participation this evening of
distinguished Members, including Mr. Higgins of western New York. And
certainly, without a doubt, Buffalo is one of the leading centers not
only in this Nation but across the globe in medical technology and
medical research, and extremely high-quality institutions of medical
care.
Of course, there is the work of the House Energy and Commerce
Committee. Our committee has broad jurisdiction over Federal agencies
and policies important to health care, to medical research, and to the
life sciences sectors.
I also have the honor of serving as the Republican chair of the Rare
Disease Caucus, another mantle by which we discuss needs and ideas in
the cancer support community. I am joined in that caucus with the
Democratic chair, Congressman Crowley of the great city of New York.
One of the major endeavors of the Energy and Commerce Committee will
be to pursue an initiative of Chairman Upton's that he has titled,
``The 21st Century Cures,'' an effort that aims to accelerate the pace
of cures and medical breakthroughs here in the United States.
For the first time, Congress will take a comprehensive look at the
full arc of accelerating cures, from the discovery of clues in basic
science to streamlining the drug and device development process to
unleashing the power of medicine in the treatment delivery phase.
{time} 2015
In one of the inaugural hearings this week, the incredible
advancements in cancer research were discussed, and the great
opportunities presented to advance new cures and treatments for other
diseases were discussed.
The committee will focus on the cycle of discovery, development, and
delivery that saves lives. We, in Congress, want to work effectively
and efficiently and ensure that there is no gap between 20th century
science and the Washington regulatory process.
ASCO is well-positioned for the type of 21st century science the
committee is working to facilitate: accelerating the pace of clinical
cancer research, establishing a new approach to therapeutic development
and new technologies to obtain a greater understanding of cancer
biology, and the needs that Congress and the administration are willing
to work together for solutions to the market.
Let me say, Mr. Speaker, that we are anxious to work with the
administration, and we want to be a partner with the executive branch,
making sure that we work as effectively as possible in fighting cancer.
This is, by no means, a partisan matter; and, indeed, it goes beyond
being a bipartisan matter. It is really nonpartisan in nature.
Besides providing better outcomes for patients, benefits of more
rigorous trial designs include the ability to design smaller and
smarter clinical trials that can be conducted faster than larger trials
that aim for smaller benefits for patients.
These steps represent significant new momentum toward a 21st century
research system that realizes the potential of precision medicine. As
we personalize medicine in this country, it is based, in no small
measure, on precision medicine; and this, again, is the wave of the
future.
On these critical public health issues, the public and private sector
have worked together to make a difference in improving the highest
quality of health care, the highest quality that the American people
deserve.
Congress is contributing by giving public research the 21st century
tools to compete on the global stage and empowering private innovators
to solve these great complexities in American laboratories. This is how
Congress should work, together, on issues that make a lasting
difference.
Too often, Mr. Speaker, we are viewed as divisive, as overly
partisan, as not coming together on the great issues confronting the
American Nation. Let me make as clear as possible, on the fight against
cancer, we are working closely together; and we are working with our
partners in the nonprofit sector and our partners in the private
sector.
This is a three-legged stool. One of those legs--indispensable--is
the involvement of the Federal Government, particularly through NIH,
but through other agencies as well and through our oversight capacity
here in Congress, making sure that drugs are brought to market as
quickly as possible with, of course, recognizing that paramount is the
safety of those drugs brought to market.
ASCO and those of us in the Congress and leaders in the life science
industries renew our commitment to the millions of patients and their
families who will benefit from more timely access to innovative medical
technologies.
More than 40 years ago, President Nixon declared a war on cancer, and
tremendous advances have been made from that initial declaration of
war; but the war has not yet been fully won, and it is our
responsibility, in our generation, to make sure we do as much as
possible so that that war will be won.
While we do not know the cure for all cancers, we do know that
awareness is the best protection, and well-rounded care during and
after treatment is the best therapy.
These burdens often fall on loved ones. I am thankful for the
families and the advocates whose challenges we may never understand
fully, but whose commitment to loved ones is unyielding and inspiring.
To ASCO and the other heroes of cancer care, I thank you for all that
you have done and all that you will continue to do. We are here, in
Congress, in a bipartisan capacity, to help give you the tools you need
to succeed in the fight against cancer.
Mr. Speaker, I yield to the distinguished gentleman from New York
(Mr. Higgins).
Mr. HIGGINS. Mr. Speaker, I want to thank my colleague from New
Jersey for his leadership on this issue, for his eloquent opening, and
I want to echo his sentiments in congratulating the American Society of
Clinical Oncology.
As my colleague has said, we have made major advancements in cancer
research in this country. Thirty years ago, less than 50 percent of
those who were diagnosed with cancer lived beyond 5 years of their
diagnosis. Today, it is over 65 percent for adults and over 80 percent
for children.
Historically, you had, really, three options with cancer. You could
burn it out through radiation, you could cut it out through surgery, or
you could poison the fast-growing cancer cells; but the problem is you
were also killing healthy cells, as well, through chemotherapy.
Today, because of medical research, we now have smart drugs, drugs
that will attack fast-growing cancer cells, without attacking fast-
growing healthy cells.
We also have a number of clinical trials going on, including right in
Buffalo, New York, at Roswell Park Cancer Institute, clinical trials
for vaccines that treat the body's dendritic cells toward the goal of
helping the body naturally fight cancer.
We have made major progress, but as my friend from New Jersey has
said, we still have much further to go.
People realize that early detection is very, very important in
effectively treating cancer. Less than 10 percent of cancer deaths
occur from the original tumor.
It is when cancer metastasizes, when it grows, when it advances to a
vital organ that we need, is when cancer becomes lethal. That is why it
is important for early detection, which will dramatically increase the
survival rate of cancer patients.
As the gentleman from New Jersey also indicated, Buffalo and western
New York is home to Roswell Park Cancer Institute, the first
comprehensive cancer center in the entire Nation.
Roswell Park gave the Nation and the world chemotherapy in 1904. It
gave the Nation and the world the prostate-specific antigen test, the
PSA test, to detect prostate cancer; and it also did groundbreaking
work in the link between tobacco use and smoking and cancer.
[[Page H4011]]
One of every three women in this Nation will develop invasive cancer
in their lifetime. One of every two men, during their lifetime, will
develop invasive cancer. The incidence is higher for men because they
smoke more.
We have a long way to go. We have made major progress. The gentleman
had said Richard Nixon had declared a war on cancer in 1971, and that
was a major, major initiative on the part of the Federal Government.
What we know also, from cancer research, is the only failure in that
research is when you quit or you are forced to quit because of lack of
funding.
A lot of these new drugs that are coming to market today have been in
various phases of discovery for the past 20 years, so to sustain cancer
research is to produce promising new therapies, but to also encourage
young researchers to stay in the field.
That is our obligation, as Democrats and Republicans of this body, in
recognizing that we must fully fund the National Institutes of Health
and the National Cancer Institute.
Mr. LANCE. I thank the gentleman.
Mr. Speaker, I now yield to the gentleman from Tennessee (Mr.
Fleischmann).
Mr. FLEISCHMANN. Mr. Speaker, to my distinguished colleagues from New
Jersey and from New York, I thank both of you all for addressing this
issue, which is of national importance.
What both of my colleagues have said, Mr. Speaker, is correct. Cancer
is a hideous disease, and we need a national commitment to beat this
horrific disease.
I want to talk tonight to the American people about a personal
experience that I had with cancer. At the same time, I want to also, as
my distinguished colleagues did, honor the American Society of Clinical
Oncology for their efforts to fight cancer.
When I was 9 years old, my mother developed breast cancer. I was more
worried about playing baseball, being a kid; and I can remember vividly
the doctor saying: your mother has cancer.
My parents were from the World War II generation. My mother was born
in 1922, my dad in 1925, and they did not have a formal education; but
I knew something was very wrong that night, and I knew my mother was
going to have breast cancer surgery, but I didn't know what cancer was.
We had hoped and prayed that she would get better. Well, about 2
years later, unfortunately, that cancer did metastasize. At the time,
my father was working away several hundred miles to keep a job, and I
was an only child, and I can remember my mother waking up screaming in
pain.
Actually, I didn't realize the cancer had come back, and actually, I
called my dad, at that time, who was working in Pittsburgh; and
basically, he called the surgeon, and the surgeon said: bring her on
in, but I think the cancer is back.
Unfortunately, despite some chemotherapy and treatment, she lost that
battle to cancer when I was 13 years old. I was a freshman in high
school. That so impacted my life, my father's life, our entire outlook
about cancer.
My father came from a generation where a cancer diagnosis was a death
sentence, sadly. I can remember him crying when my mother was first
diagnosed. He was crying uncontrollably, and I didn't understand why.
He said: no, no, no, this is going to be awful.
Sadly, it was. Interestingly enough, my father did live to the ripe
old age of 87\1/2\, but I was before my subcommittee--and for the
people watching tonight, I serve on the House Appropriations Committee,
and one of my subcommittees is the Labor, Education, and Health and
Human Services Committee, which actually funds the National Institutes
of Health and the National Cancer Institute.
So for those watching--and I applaud my colleague from New Jersey
when he was talking about all the other committees, but this committee
actually funds research, and it is so, so critically important.
I was actually talking to the head of the NIH at that day and went
outside and got a call from my father's doctor. He indicated that my
father had an esophageal cancer.
Again, despite the fact that I was almost 50 years old and had a law
degree, I didn't understand the gravity of that.
Fortunately, in this great body, in the House of Representatives, I
serve with some very fine doctors, men and women who are outstanding
doctors. I sat down with some of them, and they told me the gravity of
the situation.
Sadly, my father lost that battle to esophageal cancer in 3 months. I
went with him to the doctor, and I saw him through that process, and it
was a sad process.
{time} 2030
What we all know, this story that I have shared and that I have
experienced has been experienced by millions of Americans. And sadly,
the statistics show that cancer is on the rise, the incidence of cancer
is on the rise.
Again, my colleagues alluded to the fact that President Nixon
declared war on cancer many years ago. Well, this is a war that is
ongoing, and this is a fight that we cannot lose. America ought to lead
the way.
In this body, we control spending. We should control the spending.
But I think sometimes about all of the waste, fraud, and abuse,
duplicative programs and the like where we could actually show a great
resolve--not as Republicans, not as Democrats, but as Americans--to
beat this hideous disease. And I do want to commend the men and women
who are oncologists who fight this fight every day.
In my district, the Third District of Tennessee, I have some very
fine cities. One of those cities is Oak Ridge. And in Oak Ridge is the
Oak Ridge National Laboratory, and that laboratory is doing
groundbreaking cancer research. So there is a Federal component to
this. Our great universities are fighting this great fight.
And when I have young men and women come to me and say, ``What should
I do when I grow up?'' I suggest medicine. It is a noble profession. It
still is.
I feel sorry for a lot of the folks who are doctors today because
they are facing a lot of challenges, and I think this body ought to
resolve to help that profession so that profession, including the
oncologists, can continue to provide the health care necessary to fight
cancer and other diseases.
But as we move forward as a nation, I would just hope that we would
stop and think about the magnitude of the effect of this horrific
disease. Cancer one is not cancer two. There is no question about that.
We have made tremendous strides toward several cancers, and that is
great. We need to defeat breast cancer, but we need to defeat all
cancers.
I was so sad to learn that the fight against so many cancers has
still been futile. There are so many cancers out there that the success
or survival rate is still so low. And I have learned that, actually, as
a Congressman.
For those watching, I know our popularity and our numbers in this
body sometimes are not that high, but I want to assure the American
people that one of the things I do best and I think my colleagues do
best is we get educated. People come from around the world, from around
the country, constituents, oncologists, doctors, scientists, and they
educate us, Mr. Speaker. They educate us about the progress being made
on cancer or, sadly, in some cases, the lack of progress being made.
So it is my commitment not only to my constituents, but to all
Americans. And I am proud to serve in this body. This is the people's
House. This is a wonderful, wonderful body. Our Founding Fathers gave
us this body, and our men and women who are fighting to preserve our
freedoms in uniform every day allow us to have the great debates that
go on in this Chamber.
But there must be a resolve, Mr. Speaker, to defeat cancer. We can do
it. The cure for cancer is out there. The strides are being made. And
as we work together as Americans, I sincerely hope that we can beat
this hideous disease and help the men and women who are going through
this and their families. The toll on families is horrific. I saw that
as a young boy. I saw it as an adult man.
So, again, I want to thank the oncologists for fighting the good
fight. I want to thank my colleagues for allowing me to address this
issue tonight. And it is my fervent hope and prayer that we address
this, as Americans, and defeat this hideous disease.
[[Page H4012]]
Mr. LANCE. Mr. Speaker, I yield to the distinguished gentlelady from
Texas.
Ms. JACKSON LEE. I thank the distinguished Congressman from New
Jersey, Congressman Lance, for having this very special Special Order
this evening and my friends, Congressmen Brian Higgins, Chuck
Fleischmann, and John Carney, for sponsoring this evening's Special
Order to recognize the 50th anniversary of the American Society of
Clinical Oncology.
One would wonder what seven physicians were doing some 50 years ago.
And I am glad that they came together to recognize the vibrance and the
vitality of their specialty and the importance of gathering together.
They had their first real meeting with 51 physicians in November of
1964. And I am glad that they organized because, as we watch the
progression of research and care in the treatment of cancer, we owe a
great deal to them. Let me tell you why: because when they founded this
organization in 1964, cancer was perceived as largely untreatable. In
fact, even today, we still have the remnants of that fear when you get
that diagnosis.
Many people call it the big C. There is trepidation and fear. And I
would say to you that when those physicians organized in 1964, they
understood the awesome and ominous task that they had. Only a handful
of hard-to-tolerate and mostly ineffective therapies were even
available. And they organized to provide for physicians with proper
professional educational background material and the opportunity to
come together to facilitate their own improved management of patients
with neoplastic diseases, supporting collaborations in medical and
research organizations, and initiating and coordinating and cooperating
on projects of investigation.
So I am glad to celebrate them today because, in the cancer hospitals
across America--and I have the privilege of having in my community MD
Anderson. And among the work that MD Anderson does, it collaborates
with our local clinics and other hospitals because everyone knows that
everyone cannot get into a specific cancer hospital, but they may be in
a general hospital in which there is a cancer unit. Those oncologists
collaborate with the oncologists in the major cancer centers of
America.
And I simply want to thank my colleagues here because MD Anderson has
benefited from your understanding of the need for cancer research
dollars.
The NIH is an entity that we should fully fund, and I am on record to
have that funding. $32 billion is what will put that entity in a
position to do its work.
I was interested to listen to the gentleman who spoke of both his
mother and his father. And I believe when Members come to the floor and
speak of their personal and human experiences, it draws us closer to
our constituents and to our colleagues who have walked some of the
similar territories.
So as I have listened to his story, mine is different, for I heard
that diagnosis--cancer, breast cancer. And I didn't hear it quickly,
because when I suspected that my physician was calling to say that, all
of a sudden, my phone didn't work, and it was quite difficult to reach
me. I was on an airplane. I was in a meeting.
And even in this era of new research, to hear that is a startling and
overwhelming experience. But the good news is that oncologists have
grown in their research, working with the NIH over these 50 years, and
they have been able to give families and children not 100 percent,
maybe not even 90 percent, but they have been able to cut the mortality
rate of pediatric cancer. All of us know how heart-wrenching that is,
how difficult it is to see a child suffer with cancer.
There was a story in my local newspaper. I talked with one of my
neighbors a distance away from my community who, sadly, lost their 3-
year-old. The community gave that 3-year-old a princess parade some
months ago; and, sadly, she lost her life. It is heart-wrenching to see
a family member suffer without relief.
But yet, through the oncologists and their research and the work that
we are doing here in the United States Congress to support that
research, we have been able to impact pediatric cancer. We have been
able to work to impact breast cancer. And I have continued to work to
highlight the idea that cancer, in all of its forms, can ultimately be
cured.
I would like to cite the physicians at MD Anderson. I visited with
one today who talked about the new attitude that they have and wanting
to get woven into care a large sector of preventative care because they
realize that we are living longer. And by living longer, that is a
plus, but they are recognizing that more elderly are now susceptible to
cancer in their older years and, therefore, we need research,
preventative care to be able to get in front of that so that the cost
of saving their life can be the amount needed to do so, but that we can
put a stop to them losing their life because we have engaged in
preventative care.
So I have offered amendments on something called the triple-negative
breast cancer. It is one of the most deadly aspects of breast cancer.
It impacts minority women, African American and Hispanics, white women
and Asians, all women.
I remember being in a breast cancer walk, and a young woman came up
to me who, I guess, had been reading everything about it. She hugged me
and said, ``I am here to walk for my mother. I saw what you are doing
for triple-negative''--a Hispanic young woman. ``She did not make it,
but thank you.''
That is how families are. They are so grateful for any recognition of
the pain that they went through, that even if they lost their loved
one, they are so happy that maybe you are doing something to help
others. So I am glad that we are here tonight to be able to acknowledge
oncologists who are the very ones who would come and bring forward
these new ideas.
Might I just briefly say these few points: one, with respect to
triple-negative breast cancer, between 10 and 17 percent of female
breast cancer patients have triple-negative. It is three times more
likely to cause death than the most common form of breast cancer.
Seventy percent of women with metastatic triple-negative breast cancer
do not live more than 5 years after being diagnosed. There is no
targeted treatment available. The American Cancer Society calls this
particular strain of breast cancer ``an aggressive subtype associated
with lower survival rates.''
But the good news is that in my conversations with MD Anderson, among
the many finite research areas that they are doing, they have included
triple-negative breast cancer. I know that those oncologists are going
to give us a new day.
So Congressman Lance, I thank you for honoring now 50 years of
oncologists working to ensure that there is a cure. And I want to
acknowledge Dr. DePinho, who is the new CEO of MD Anderson, his wife
and the amazing research that she is doing, and all of the oncologists
there.
But as I close, I would like to recognize a dear friend, MD Anderson
oncologist Dr. John Mendelsohn, who served as the CEO for any number of
years. Many of my colleagues here in the United States Congress know
him well. I call John a friend. He will be honored by the American
Society of Clinical Oncology for its 50th anniversary through the
organization's Oncology Luminary series. He is an oncologist, as we
know. He served as president of MD Anderson through an incredibly
productive period of nearly 15 years. The institution doubled in size
during his tenure and aimed at higher excellence. He has an
international reputation. And he and his collaborators in California
produced monoclonal antibody 225, which inhibits human cancer cell
proliferation by blocking the signal and pathways that are activated by
the receptors for epidermal growth factor.
There are many whom we can cite tonight, but I simply want to
celebrate that there is a specialty called oncology that could cause
more of us to answer that phone call when we are called and to receive
that diagnosis in a way that we know there is hope and that family
members will know there is hope and other family members who are now
facing a diagnosis of cancer of their loved one will have hope.
Oncologists have given us that hope as they continue to research, and
I stand ready with my colleagues to provide the right kind of research
and
[[Page H4013]]
funding for them to continue to look to save lives.
I thank the gentleman for yielding.
Mr. Speaker, I want to thank my colleagues Congressmen Leonard Lance,
Brian Higgins, Chuck Fleishmann, and John Carney for sponsoring this
evening's special order to recognize the 50th anniversary of the
American Society of Clinical Oncology.
On April 9, 1964, the American Society of Clinical Oncology held its
first organizational meeting when 7 physicians who are known as the
founders of the organization.
Fifty-one physicians attended the first meeting of the American
Society of Clinical Oncology in Chicago in November of 1964.
The ASOC supports oncologists by: providing physicians with proper
professional educational background material and the opportunity to
facilitate their own improved management of patients with neoplastic
diseases; supporting collaborations with other medical and research
organizations, national and otherwise, with a view of enhancing
professional education in the area of diagnosis and treatment of
patients with neoplastic diseases; and initiating, coordinating and
cooperating in projects of investigation of human neoplastic disease.
At the time ASCO was established in 1964, cancer was largely
untreatable. Only a handful of hard-to-tolerate and mostly ineffective
therapies were available.
I want to thank and recognize the Oncologists who serve the residents
of the City of Houston for their work and dedication in providing
treatment and care to cancer patients.
Congresswoman Jackson Lee's work on Women's Health and Safety
I introduced H.R. 80, the Triple-Negative Breast Cancer Research and
Education Act.
The bill requires the Director of the National Institutes of Health
(NIH) to expand, intensify, and coordinate programs for the conduct and
support of research on triple-negative breast cancer (breast cancers
whose cells are negative for estrogen receptors, progesterone
receptors, and the HER2 protein on their sources).
Directs the Secretary of Health and Human Services (HHS), acting
through the Director of the Centers for Disease Control and Prevention
(CDC), to develop and disseminate to the public information regarding
triple-negative breast cancer, including information on: (1) the
incidence and prevalence of such breast cancer among women, (2) the
elevated risk for minority women, and (3) the availability of a range
of treatment options.
Requires the Secretary, acting through the Administrator of the
Health Resources and Services Administration (HRSA), to develop and
disseminate information on triple-negative breast cancer to health care
providers.
Last year, I offered an amendment that was added to the House of
Representatives' Department of Defense Authorization bill that directs
the Department of Defense Office of Health to collaborate with the
National Institutes of Health to provide resources to identify specific
genetic and molecular targets and biomarkers for TNBC.
Triple Negative Breast Cancer (TNBC)
Triple-negative breast cancer (TNBC) is a term used to describe
breast cancers whose cells do not have estrogen receptors and
progesterone receptors, and do not have an excess of the ``HER2''
protein on their cell membrane of tumor cells.
Between 10-17% of female breast cancer patients have the triple
negative subtype.
Three times more likely to cause death than the most common form of
breast cancer, 70% of women with metastatic triple negative breast
cancer do not live more than five years after being diagnosed.
There is no targeted treatment available for TNBC. The American
Cancer Society calls this particular strain of breast cancer ``an
aggressive subtype associated with lower survival rates.''
Triple Negative Breast Cancer (TNBC) cells are usually of a higher
grade and size; Onset at a younger age; More aggressive; and more
likely to metastasize
TNBC is in fact a heterogeneous group of cancers with varying
differences in prognosis and survival rate between various subtypes.
This has led to a lot of confusion amongst both physicians and
patients.
Apart from surgery, cytotoxic chemotherapy is the only available
treatment; targeted molecular treatments while being investigated are
not accepted treatment.
Populations Affected by TNBC
TNBC disproportionately impacts younger women, African American
women, Hispanic/Latina women, and women with a ``BRCA1'' genetic
mutation, which is prevalent in Jewish women.
TNBC usually affects women under 50 years of age.
More than 30% of all breast cancer diagnoses in African American
women are of the triple negative variety. Black women are far more
susceptible to this dangerous subtype than white or Hispanic women.
Women with TNBC are more likely to have distance metastases in the
brain and lung and more common subtypes of breast cancer.
Breast cancers with specific, targeted treatment methods, such as
hormone and gene based strains, have higher survival rates than the
triple negative subtype, highlighting the need for a targeted
treatment.
Houston is home to MD Anderson
I would like recognize MD Anderson Oncologist Dr. John Mendelsohn who
will be honored by the American Society of Clinical Oncology for its
50th anniversary through the organization's ``Oncology Luminaries''
series.
Dr. Mendelsohn is an Oncologist at MD Anderson, which is located in
the city of Houston Texas.
Dr. Mendelsohn served as president of MD Anderson through an
incredibly productive period of nearly 15 years. The institution more
than doubled in size during his tenure, while aiming for even higher
excellence in patient care and research.
Dr. Mendelsohn brought to MD Anderson an international reputation for
his research on how the binding of growth factors to receptors on the
surface of cells regulates cell functions.
He and his collaborators in California produced monoclonal antibody
225, which inhibits human cancer cell proliferation by blocking the
signaling pathways that are activated by the receptors for epidermal
growth factor.
His subsequent research in the laboratory and the clinic pioneered
the universally adopted concept of anti-receptor therapy that targets
key cell signaling pathways as a new form of cancer treatment.
I join my colleagues in honoring and recognizing the important
contribution to advances in cancer treatment made possible by the
American Society of Clinical Oncology.
Mr. LANCE. Mr. Speaker, I think the impassioned remarks of my
distinguished colleague from Texas are an indication of her tremendous
advocacy on behalf of this issue, not only for her constituents, not
only for all of the residents of the great State of Texas, but, indeed,
for the entire American people.
{time} 2045
Mr. Speaker, my distinguished colleague from Texas spoke movingly
about breast cancer. Yesterday, I spoke to a group of advocates
dedicated to the treatment of breast cancer and working to ensure that
women are educated about breast reconstruction surgery and care options
following cancer treatments.
These advocates, working out of love for their mothers, daughters,
sisters, and wives, have championed the Breast Cancer Patient Education
Act, which will take an educational approach to breast cancer treatment
and allow women to have full access to their options.
Since 1998, health care plans that offer breast cancer coverage have
been required to provide breast reconstruction surgery and prostheses.
Surprisingly, however, Mr. Speaker, recent studies report that up to 70
percent of women eligible for breast reconstruction following cancer
treatment are not fully informed of their reconstruction and care
options by their general surgeon, and this is particularly true in
minority communities.
Many of these advocates have been through great challenges
personally, and I have heard both here in Washington and in my offices
in New Jersey the stories of fear and insecurity that come with the
diagnosis, as the distinguished gentlelady from Texas has indicated,
and the despair of having so many questions and too few answers. I hope
that at an early date the Congress will pass the Breast Cancer Patient
Education Act to work to change that.
In another area of cancer that we have not mentioned this evening, I
have worked with colleagues on both sides of the aisle regarding
pancreatic cancer, and I know oncologists are fighting hard against
this very virulent form of cancer. The survival rate for pancreatic
cancer, Mr. Speaker, unfortunately, has not increased in 40 years, and
the 5-year survival rate, as I understand it, is 7 percent.
It is incumbent upon those of us here in Congress to ensure that NIH
and those involved in cancer research at the Federal level do as good a
job as possible regarding pancreatic cancer. I acknowledge this evening
all of those who are working in that area, as well. The ASCO founded 50
years ago has a great, great history over these last five decades, but
much more needs to be done, and we will do it together.
I conclude this evening, Mr. Speaker, on a personal note. I have a
twin brother, and we lost our mother to breast
[[Page H4014]]
cancer when we were 12 years old. Now, this was almost 50 years ago.
Just think of the tremendous progress that has been made in the last 50
years, certainly with the leadership of the ASCO. But more progress
needs to be made. And to all of us who have been affected, either
personally or familially, based upon our family, regarding the issue of
cancer, we stand here on the floor of the House to work together in
this bipartisan capacity--and might I suggest nonpartisan capacity--to
make sure that as we move forward we move forward together in what I
know will be a successful fight.
We will win the war against cancer. We will win it working together
in the best traditions of the American Nation. Mr. Speaker, I yield
back the balance of my time.
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