[House Hearing, 118 Congress]
[From the U.S. Government Publishing Office]


                EXAMINING PROPOSALS THAT PROVIDE ACCESS 
                 TO CARE FOR PATIENTS AND SUPPORT RE-
                 SEARCH FOR RARE DISEASES

=======================================================================

                                HEARING

                               BEFORE THE

                         SUBCOMMITTEE ON HEALTH

                                 OF THE

                    COMMITTEE ON ENERGY AND COMMERCE
                        HOUSE OF REPRESENTATIVES

                    ONE HUNDRED EIGHTEENTH CONGRESS

                             FIRST SESSION

                               __________

                             JUNE 14, 2023

                               __________

                           Serial No. 118-48
                           
[GRAPHIC NOT AVAILABLE IN TIFF FORMAT]                           


     Published for the use of the Committee on Energy and Commerce

                   govinfo.gov/committee/house-energy
                        energycommerce.house.gov
                        
                                __________

                   U.S. GOVERNMENT PUBLISHING OFFICE                    
57-131 PDF                  WASHINGTON : 2025                  
          
-----------------------------------------------------------------------------------                         
 
                    COMMITTEE ON ENERGY AND COMMERCE

                   CATHY McMORRIS RODGERS, Washington
                                  Chair
MICHAEL C. BURGESS, Texas            FRANK PALLONE, Jr., New Jersey
ROBERT E. LATTA, Ohio                  Ranking Member
BRETT GUTHRIE, Kentucky              ANNA G. ESHOO, California
H. MORGAN GRIFFITH, Virginia         DIANA DeGETTE, Colorado
GUS M. BILIRAKIS, Florida            JAN SCHAKOWSKY, Illinois
BILL JOHNSON, Ohio                   DORIS O. MATSUI, California
LARRY BUCSHON, Indiana               KATHY CASTOR, Florida
RICHARD HUDSON, North Carolina       JOHN P. SARBANES, Maryland
TIM WALBERG, Michigan                PAUL TONKO, New York
EARL L. ``BUDDY'' CARTER, Georgia    YVETTE D. CLARKE, New York
JEFF DUNCAN, South Carolina          TONY CARDENAS, California
GARY J. PALMER, Alabama              RAUL RUIZ, California
NEAL P. DUNN, Florida                SCOTT H. PETERS, California
JOHN R. CURTIS, Utah                 DEBBIE DINGELL, Michigan
DEBBBIE LESKO, Arizona               MARC A. VEASEY, Texas
GREG PENCE, Indiana                  ANN M. KUSTER, New Hampshire
DAN CRENSHAW, Texas                  ROBIN L. KELLY, Illinois
JOHN JOYCE, Pennsylvania             NANETTE DIAZ BARRAGAN, California
KELLY ARMSTRONG, North Dakota, Vice  LISA BLUNT ROCHESTER, Delaware
    Chair                            DARREN SOTO, Florida
RANDY K. WEBER, Sr., Texas           ANGIE CRAIG, Minnesota
RICK W. ALLEN, Georgia               KIM SCHRIER, Washington
TROY BALDERSON, Ohio                 LORI TRAHAN, Massachusetts
RUSS FULCHER, Idaho                  LIZZIE FLETCHER, Texas
AUGUST PFLUGER, Texas
DIANA HARSHBARGER, Tennessee
MARIANNETTE MILLER-MEEKS, Iowa
KAT CAMMACK, Florida
JAY OBERNOLTE, California
                                 ------                                

                           Professional Staff

                      NATE HODSON, Staff Director
                   SARAH BURKE, Deputy Staff Director
               TIFFANY GUARASCIO, Minority Staff Director
                        
                        
                        Subcommittee on Health

                        BRETT GUTHRIE, Kentucky
                                 Chairman
                                 
MICHAEL C. BURGESS, Texas            ANNA G. ESHOO, California
ROBERT E. LATTA, Ohio                  Ranking Member
H. MORGAN GRIFFITH, Virginia         JOHN P. SARBANES, Maryland
GUS M. BILIRAKIS, Florida            TONY CARDENAS, California
BILL JOHNSON, Ohio                   RAUL RUIZ, California
LARRY BUCSHON, Indiana, Vice Chair   DEBBIE DINGELL, Michigan
RICHARD HUDSON, North Carolina       ANN M. KUSTER, New Hampshire
EARL L. ``BUDDY'' CARTER, Georgia    ROBIN L. KELLY, Illinois
NEAL P. DUNN, Florida                NANETTE DIAZ BARRAGAN, California
GREG PENCE, Indiana                  LISA BLUNT ROCHESTER, Delaware
DAN CRENSHAW, Texas                  ANGIE CRAIG, Minnesota
JOHN JOYCE, Pennsylvania             KIM SCHRIER, Washington
DIANA HARSHBARGER, Tennessee         LORI TRAHAN, Massachusetts
MARIANNETTE MILLER-MEEKS, Iowa       FRANK PALLONE, Jr., New Jersey (ex 
JAY OBERNOLTE, California                officio)
CATHY McMORRIS RODGERS, Washington 
    (ex officio)
                             C O N T E N T S

                              ----------                              
                                                                   Page
Hon. Brett Guthrie, a Representative in Congress from the 
  Commonwealth of Kentucky, opening statement....................     1
    Prepared statement...........................................     3
Hon. Michael C. Burgess, a Representative in Congress from the 
  State of Texas, prepared statement.............................    +6
Hon. Anna G. Eshoo, a Representative in Congress from the State 
  of California, opening statement...............................    10
    Prepared statement...........................................    12
Hon. Cathy McMorris Rodgers, a Representative in Congress from 
  the State of Washington, opening statement.....................    14
    Prepared statement...........................................    16
Hon. Frank Pallone, Jr., a Representative in Congress from the 
  State of New Jersey, opening statement.........................    21
    Prepared statement...........................................    23

                               Witnesses

Elizabeth Cherot, M.D., Senior Vice President and Chief Medical 
  and Health Officer, March of Dimes.............................    25
    Prepared statement...........................................    28
    Answers to submitted questions...............................   206
Alexis Thompson, M.D., Chief of Division of Hematology, Elias 
  Schwartz, M.D., Endowed Chair in Hematology, Children's 
  Hospital of Philadelphia,......................................    45
    Prepared statement...........................................    47
    Submitted questions for the record \1\.......................   209
Meredithe McNamara, M.D., Assistant Professor, Yale School of 
  Medicine.......................................................    52
    Prepared statement...........................................    54
    Answers to submitted questions...............................   211
Miriam Grossman, M.D., Child, Adolescent, and Adult Psychiatry...    58
    Prepared statement...........................................    60
    Submitted questions for the record \1\.......................   219
George Manahan, Parkinson's Advocate and Patient.................    71
    Prepared statement...........................................    73
Kevin O'Connor, Assistant to the General President for Government 
  Affairs and Political Action, International Association of Fire 
  Fighters.......................................................    78
    Prepared statement...........................................    80

----------

\1\ Dr. Thompson and Dr. Grossman did not answer submitted questions 
for the record by the time of publication. Replies received after 
publication will be retained in committee files and made available at 
https://docs.house.gov/Committee/Calendar/ByEvent.aspx?EventID=116121.

                            Legislation \2\

H.R. 3226, the PREEMIE Reauthorization Act of 2023
H.R. 3838, the Preventing Maternal Deaths Reauthorization Act of 
  2023
H.R. ___, the Action for Dental Health Act of 2023
H.R. 3884, the Sickle Cell Disease and Other Heritable Blood 
  Disorders Research, Surveillance, Prevention, and Treatment Act 
  of 2023
H.R. ___, the Firefighter Cancer Registry Reauthorization Act of 
  2023
H.R. 2365, the National Plan to End Parkinson's Act
H.R. 3391, the Gabriella Miller Kids First Research Act 2.0
Discussion Draft, H.R. ___, the Children's Hospital GME Support 
  Reauthorization Act of 202360
H.R. ___, the Medicaid Primary Care Improvement Act

                           Submitted Material

Inclusion of the following was approved by unanimous consent.
List of documents submitted for the record.......................   138
Statement of the Sickle Cell Disease Partnership by Brett Giroir, 
  M.D., Senior Advisor, June 14, 2023............................   139
Letter of June 14, 2023, from the Sickle Cell Disease Partnership 
  to Mrs. Rodgers and Ms. Eshoo..................................   140
Letter of June 14, 2023, from Sick Cells to Mr. Guthrie and Ms. 
  Eshoo..........................................................   142
Statement of The Michael J. Fox Foundation for Parkinson's 
  Research, June 14, 2023........................................   145
Statement of the Direct Primary Care Coalition by Troy Burns, 
  M.D., June 14, 2023............................................   151
Study, ``Hormone Therapy, Mental Health, and Quality of Life 
  Among Transgender People: A Systematic Review,'' by Kellan E. 
  Baker, et al., Journal of Endocrine Society, 2021, Vol. 5, No. 
  4..............................................................   159
Statement of the Yale School of Medicine, ``Flawed Medicaid 
  Report in Florida''............................................   175
Research paper, ``Biased Science: The Texas and Alabama Measures 
  Criminalizing Medical Treatment for Transgender Children and 
  Adolescents Rely on Inaccurate and Misleading Scientific 
  Claims,'' by Susan Boulware, et al., Yale School of Law, April 
  28, 2022 \3\
Letter of June 14, 2023, from Barbara Jones, President and Chief 
  Executive Officer, and Micah Niermann, M.D., Executive Vice 
  President of Clinical Affairs and Chief Medical Officer, 
  Gillette Children's Specialty Healthcare, to Mr. Guthrie and 
  Ms. Eshoo......................................................   176
Letter of June 9, 2023, from AIDS Action Baltimore, et al., to 
  Mr. Burgess, et al.............................................   178
Study, ``A Surgical Simulation Module on Pediatric Femoral 
  Osteotomies for Orthopaedic Surgery Residents,'' by Zachary A. 
  Quanbeck, M.D., et al., Journal of the Pediatric Orthopaedic 
  Society of North America, Volume 4, Number 51, August 2022.....   182
Letter of June 14, 2023, from Mary R. Grealy, President, 
  Healthcare Leadership Council, to Mr. Guthrie and Ms. Eshoo....   194
Statement of the Children's Hospital Association, June 14, 2023..   196
Statement of Hon. Bill Pascrell, Jr., a Representative in 
  Congress from the State of New Jersey, June 14, 2023...........   198
Statement of interACT by Erika Lorshbough, Executive Director, 
  June 14, 2023..................................................   200
Statement of Hon. Jennifer Wexton, a Representative in Congress 
  from the Commonwealth of Virginia, June 14, 2023...............   202
Letter of June 8, 2023, from George R. Shepley, President, and 
  Raymond A. Cohlmia, Executive Director, American Dental 
  Association, to Mr. Guthrie and Ms. Eshoo......................   204

----------

\2\ Text of the legislation has been retained in committee files and is 
available at https://docs.house.gov/Committee/Calendar/
ByEvent.aspx?EventID=116121.
\3\ The research paper has been retained in committee files and is 
available at https://docs.house.gov/Committee/Calendar/
ByEvent.aspx?EventID=116121.

 
   EXAMINING PROPOSALS THAT PROVIDE ACCESS TO CARE FOR PATIENTS AND 
                   SUPPORT RESEARCH FOR RARE DISEASES

                              ----------                              


                        WEDNESDAY, JUNE 14, 2023

                  House of Representatives,
                            Subcommittee on Health,
                          Committee on Energy and Commerce,
                                                    Washington, DC.
    The subcommittee met, pursuant to call, at 10:32 a.m., in 
room 2322 Rayburn House Office Building, Hon. Brett Guthrie 
(chairman of the subcommittee) presiding.
    Members present: Representatives Guthrie, Burgess, Latta, 
Griffith, Bilirakis, Johnson, Bucshon, Hudson, Carter, Dunn, 
Pence, Crenshaw, Joyce, Harshbarger, Miller-Meeks, Obernolte, 
Rodgers (ex officio), Eshoo (subcommittee ranking member), 
Sarbanes, Cardenas, Ruiz, Dingell, Kuster, Kelly, Barragan, 
Craig, Schrier, Trahan, and Pallone (ex officio).
    Also present: Representatives Schakowsky and Tonko.
    Staff present: Kristen Ashford, Fellow, Health; Jolie 
Brochin, Clerk, Health; Sarah Burke, Deputy Staff Director; 
Kristin Flukey, Professional Staff Member, Health; Grace 
Graham, Chief Counsel, Health; Nate Hodson, Staff Director; 
Tara Hupman, Chief Counsel; Emily King, Member Services 
Director; Molly Lolli, Counsel, Health; Karli Plucker, Director 
of Operations (shared staff); Michael Taggart, Policy Director; 
Lydia Abma, Minority Policy Analyst; Jacquelyn Bolen, Minority 
Health Counsel; Waverly Gordon, Minority Deputy Staff Director 
and General Counsel; Tiffany Guarascio, Minority Staff 
Director; Mackenzie Kuhl, Minority Digital Manager; Una Lee, 
Minority Chief Health Counsel; and Tristen Tellman, Minority 
Health Fellow.
    Mr. Guthrie. The subcommittee will come to order, and I 
recognize myself for 5 minutes for an opening statement.

 OPENING STATEMENT OF HON. BRETT GUTHRIE, A REPRESENTATIVE IN 
           CONGRESS FROM THE COMMONWEALTH OF KENTUCKY

    Today we are here to discuss legislation about access to 
care and improve health outcomes for Americans. We will 
consider bills to help support innovation for therapies and 
lifesaving cures for rare diseases which affect more than 30 
million Americans. That is why we are considering H.R. 3391, 
the Gabriella Miller Kids First Research Act 2.0, which would 
reauthorize the National Institutes of Health Gabriella Miller 
Kids First Pediatric Research Program.
    We are also considering H.R. 3226, the PREEMIE 
Reauthorization led by Ranking Member Eshoo and Representative 
Miller-Meeks, Kelly, Kiggans, Blunt Rochester, and Burgess. We 
are also--have more work to do to protect the long-term health 
and well-being of expecting and new moms. We will consider to 
build off this work the subcommittee has done over the past 
several years to address maternal mortality.
    H.R. 3838, the Preventing Maternal Deaths Reauthorization 
Act, will continue the work done by the CDC and the Health 
Resources and Service Administration, HRSA, to provide access 
to resources for women experiencing risky pregnancies and 
develop best practices to treat at-risk moms.
    We are also considering H.R. 3821, the Firefighter Cancer 
Registry Reauthorization Act. Our first responders experience 
adverse health outcomes often resulting from selfless and brave 
work they do to keep us and our loved ones safe. We are also 
considering legislation to advance our knowledge of rare 
diseases and promote access to therapies to treat rare diseases 
such as sickle cell and Parkinson's disease.
    As I step forward to address the issues today, we are 
examining H.R. 384--3884, the Sickle Cell Disease and Other 
Heritable Blood Disorders Research, Surveillance, Prevention, 
and Treatment Act, and H.R. 2365, the National Plan to End 
Parkinson's Act. I would like to thank Representatives Burgess 
and Bilirakis for their leadership on these bills. And, 
fortunately, as we are seek--as we have these breakthroughs, we 
absolutely need to make sure that people have access to them, 
and so we have our--that we had in the hearing last week, the 
MVP bill that hopefully we can all come together to make sure 
that the least of us have access to these lifesaving therapies 
through the Medicaid Program.
    And last, we are considering H.R. 3887, the Children's 
Hospital GME Support Reauthorization Act of 2023. This program 
provides funding the children's hospitals to help train 
resident physician and dentists. It is critical for us to 
reauthorize the program before the end of the fiscal year with 
the necessary policy changes to keep kids safe from 
experimental procedures.
    In closing, I am proud of these bipartisan bills before us 
that will approve access to care and drive innovation. Patients 
and their families will be better off because of the work we 
are doing today.
    [The prepared statement of Mr. Guthrie follows:]
    [GRAPHICS NOT AVAILABLE IN TIFF FORMAT]
    
    Mr. Guthrie. And I will yield my remaining time to Dr. 
Burgess.
    Mr. Burgess. And I thank the Chair for the recognition.
    So I am--it is so important that we are considering the 
reauthorization of the PREEMIE Act introduced by my good 
friends Anna Eshoo and Mary Miller-Meeks along with several 
other Members. The PREEMIE Act would reauthorize programs that 
expand research, education, and intervention activities aimed 
at reducing premature births and treating the complications of 
prematurity.
    You know, we are just a few weeks away from the 60th 
anniversary of the birth of the last child in the White House. 
Patrick Kennedy was born August 7, 1963. Unfortunately, he did 
not live too long because of complications of prematurity. And 
indeed, his father, the President of the United States, tried 
to enlist help from all sectors in the medical community in 
order to save his son, but he was unsuccessful.
    Writing in his great book, William Manchaster, in detailing 
the life and death of President Kennedy, he talked about that 
trip to Dallas. The day before the trip to Dallas, the 
President was in San Antonio. In San Antonio, he was shown an 
experiment that was going on regarding high-altitude 
physiology. There were four men in a container, and they were 
being simulated 30,000 feet, and they were being given high 
oxygen.
    The President pulled the investigator aside, and according 
to Mr. Manchester's book, he drew Dr. Welch aside. He had one 
more inquiry. ``Apart from space research, there must be other 
medical implications here. Do you think your work might improve 
oxygen chambers for, say, premature babies?'' Clearly, his 
experience was very much on his mind that day.
    Very personal to me because, 13 years later in August of 
1976, my daughter was born a few weeks early and suffered from 
the same complications, idiopathic infantile respiratory 
distress syndrome, hyaline membrane disease, and because of the 
work that had occurred over those intervening 13 years, the 
science in neonatology, the specialty of neonatology had come 
into being and neonatal intensive care units had now occurred. 
So because of those efforts, my daughter 13 years later: short 
stay in the hospital, take your medicines, do your treatments, 
and you live a normal, healthy life.
    That is the kind of work we are talking about today. That 
is the type of work we are reauthorizing. I thank my friends 
for introducing it. This is important work as we go forward.
    [The prepared statement of Mr. Burgess follows:]
    [GRAPHICS NOT AVAILABLE IN TIFF FORMAT]
    
    Mr. Burgess. I will yield back.
    Mr. Guthrie. Thank you. Thank you for your story.
    The gentleman yields back, and I will yield back the time, 
and I now recognize the gentlelady from California, 
Representative Eshoo, for 5 minutes for an opening statement.

 OPENING STATEMENT OF HON. ANNA G. ESHOO, A REPRESENTATIVE IN 
             CONGRESS FROM THE STATE OF CALIFORNIA

    Ms. Eshoo. Thank you, Mr. Chairman, and good morning, 
colleagues, and thank you to this sterling full table of 
witnesses that we have with us today.
    Today we are considering eight proposals that increase 
access to care and reauthorize critical public health programs 
and one proposal that does exactly the opposite. I am pleased 
that my legislation, H.R. 3226, the PREEMIE Reauthorization 
Act, is included in the hearing. And I thank my coleads, 
Representatives Miller-Meeks, Kelly, Burgess, Blunt Rochester, 
and Kiggans, for their work on this important effort.
    In 2005, I introduced the original PREEMIE Act with former 
chairman of our full committee, Fred Upton, which was the first 
and remains the only law to focus solely on the prevention of 
preterm births. We need a swift reauthorization to ensure the 
successful programs created by this law can continue. 3226 will 
also improve future policy by studying the current gaps in our 
healthcare system that have led to the recent surge in preterm 
births and how we can address them.
    Our hearing will also consider critical bipartisan bills 
such as the Preventing Maternal Deaths Reauthorization Act, the 
National Plan to End Parkinson's Disease, and the Firefighter 
Cancer Registry Reauthorization Act. I see Kevin nodding there. 
But we are also considering a proposal that will damage the 
Children's Hospital's Graduate Medical Education Program 
irreparably by making hospitals choose between providing the 
standard care for children experiencing gender dysphoria or 
losing funding that keeps them afloat. There should not be a 
choice here. It should not be one or the other.
    For nearly 25 years, the CHGME Program has trained half of 
general pediatricians and a majority of pediatric specialists. 
In California, CHGME Program funds are used by seven children's 
hospitals to train over 906 full-time pediatric residents 
annually. This is an extraordinary record. It is an 
extraordinary record, something that we are proud of on both 
sides of the aisle because it has had the full support of 
Members of both sides of the aisle.
    And that is why it is difficult for me to comprehend why my 
Republican colleagues are subjecting the children's hospitals 
to a manufactured culture war that puts politics in between 
parents, children, and their pediatricians. This just shouldn't 
be here. It just shouldn't be here. Specifically, the bill 
prohibits 19 specific procedures and any type of hormone 
therapy that could be perceived as gender affirming for trans 
youth.
    This proposal threatens precious lives. It is not just a 
bunch of words on a piece of paper. As one pediatric 
endocrinologist said, ``Every time politics and medicine 
commingle, people die.'' We are already seeing higher rates of 
maternal and infant death because of abortion restrictions that 
paralyze providers in an emergency. Now Republicans are 
attempting to ban 19 more procedures and treatments that should 
be a private--a private--decision between patients, their 
families, and their doctors. This proposal also worsens the 
mental health crisis that trans children are facing.
    This is really sad, and if I had a magic wand, I would just 
wish this away. But it is something that is before the 
committee today.
    I want to close on this with this quote. I was watching the 
news one night and there was a Nebraska lawmaker--an 
independent, a woman, a mother--and this is what she said: ``I 
am asking you to love your family more than you hate mine.'' I 
hope that this issue will somehow not make it here. This 
doesn't belong here. We file--follow science. We have worked on 
a bipartisan basis to build and build and build across our 
healthcare system. So much of the decision making is private. 
That is where it belongs.
    So thank you to our panel of experts that are here today.
    [The prepared statement of Ms. Eshoo follows:]
    [GRAPHICS NOT AVAILABLE IN TIFF FORMAT]
    
    Ms. Eshoo. And I yield back.
    Mr. Guthrie. The gentlelady yields back, and the Chair now 
recognizes the Chair of the full committee, Chair Rodgers, for 
5 minutes for an opening statement.

      OPENING STATEMENT OF HON. CATHY McMORRIS RODGERS, A 
    REPRESENTATIVE IN CONGRESS FROM THE STATE OF WASHINGTON

    Mrs. Rodgers. Today's hearing looks at key programs that 
aim to improve access to care and support research for rare 
diseases. This includes solutions to help save the lives of 
mothers and babies, improve our understanding of blood 
disorders, coordinate Federal efforts related to Parkinson's 
disease, and ensure we are appropriately monitoring instances 
of cancer in firefighters so that we can get these heroes 
better treatments and care. I look forward to hearing from our 
witnesses about the effectiveness of these programs.
    As part of our work to help mothers and babies at every 
stage of life, we are continuing our work to reauthorize the 
PREEMIE and Preventing Maternal Deaths Program. Especially for 
first-time moms, I think about the joy and also the 
uncertainty, the questions, and all that comes with being 
pregnant. Across the country there is a need for stable and 
consistent resources and education around maternal health.
    That is why I was pleased to see the Preventing Maternal 
Deaths Reauthorization included a requirement for CDC and HRSA 
to share best practices to hospitals and other healthcare 
entities to ensure we are doing everything we can for moms, 
babies, and families to thrive.
    I hear often from constituents not knowing where to turn 
when dealing with postpartum depression in rural areas. HRSA 
has a national maternal mental health hotline, but getting best 
practices to doctors on how to best help women will hopefully 
lead to improvements in maternal mental health.
    We are also considering the reauthorization of the 
Children's Hospital Graduate Medical Education Program. In 
nearly 60 hospitals across the country, this program helps 
train our next generation of pediatricians. As we discuss other 
solutions today like the Gabriella Miller Kids First Research 
Act, I imagine moms and dads who hear the diagnosis no parent 
wants to hear from a doctor: ``Your child has cancer.'' And 
then for the love of their child, the parents pour themselves 
into making sure that their child will have the best chance to 
one day achieve their hopes and dreams.
    From our work on this committee, we know all families have 
experienced this. That is why we must authorize the Children's 
Hospital Program, so America's children are cared for by the 
best doctors in the world, doctors who we trust to practice 
with the strongest medicine, data, and science so our kids live 
full, happy, and healthy lives.
    We are not shying away from the concerns that children are 
being rushed to experimental medical interventions that could 
include puberty blockers, hormone therapies, and surgeries that 
cause irreversible damage. Dr. Miriam Grossman is here today to 
share the data and why other countries are stepping back from 
these interventions for children because of the risk, like 
permanent infertility, outweigh the benefits. Our children's 
hospitals and medical institutions should also be urging 
caution and being honest about where the evidence is lacking.
    Many times on this committee we have come together to 
protect the young generation. I have had many conversations 
with my colleagues about our concern for teenage girls in 
particular who are facing more stress, anxiety, and pressure 
than ever before. For them and children in crisis, we have 
taken historic action on mental healthcare reforms. We are 
leading right now to stop Big Tech's algorithms from 
manipulating children and preying on their vulnerabilities. And 
this work must continue, and we need to do everything we can to 
stand up and protect children.
    That is our goal today. Let's send a message to the young 
generation that they are loved as they are. And let's make sure 
that we are getting the best healthcare possible. They deserve 
nothing less.
    To close, I want to thank my colleagues who are leading on 
solutions we are discussing. Thank you to our witnesses for 
your time and providing your expertise this morning. We are 
grateful on this committee and, you know, this committee is 
about doing the hard work, plowing the hard ground necessary to 
legislate and to improve the lives of those that we serve.
    I look forward to the discussion.
    [The prepared statement of Mrs. Rodgers follows:]
    [GRAPHICS NOT AVAILABLE IN TIFF FORMAT]
    
    Mrs. Rodgers. And I yield back.
    Mr. Guthrie. The Chair yields back. The Chair now 
recognizes the ranking member from New Jersey, the gentleman 
from New Jersey, Rep. Pallone, for 5 minutes for an opening 
statement.

OPENING STATEMENT OF HON. FRANK PALLONE, Jr., A REPRESENTATIVE 
            IN CONGRESS FROM THE STATE OF NEW JERSEY

    Mr. Pallone. Thank you, Mr. Chairman. Today could have been 
a bipartisan hearing, but once again Republicans are playing 
political games with the healthcare of Americans, and I am 
deeply disappointed with the legislation that Republicans are 
bringing up for consideration today to reauthorize the 
Children's Hospital Graduate Medical Education Program. This 
unnecessary and discriminatory bill is going to dominate this 
hearing, which is unfortunate since there are bipartisan public 
health policies that we should also be discussing here today.
    The CHGME Program is a longstanding effort to support the 
training of pediatricians and ensure that children across the 
country have proper access to care. And this is a popular 
program. Since its inception, it has consistently received 
strong bipartisan support. In fact, reauthorization of CHGME 
has always been done in a bipartisan manner.
    Today we should be considering legislation introduced by my 
colleague, Representative Schrier, that is bipartisan 
reauthorization of this important program. But instead, 
Republicans have chosen to notice a partisan bill that includes 
language to ban medically necessary care for transgender youth.
    Now, the Republican bill goes against decades of scientific 
research and evidence that has established clear standards of 
care. Care that is effective and essential to the health and 
well-being of transgender youth. Care that is supported by the 
American Academy of Pediatrics, the American Medical 
Association, and every other leading medical association. 
Banning evidence-based care is an affront to science, and it is 
dangerous.
    So let me be clear about what is happening here. 
Republicans want to prescribe in excruciating detail in Federal 
legislation which medical treatments and care are acceptable to 
provide to young people. They are trying to overrule doctors, 
patients, and their parents.
    We know that transgender youth are already vulnerable to 
mental health challenges. Nearly one in five transgender and 
nonbinary youth have attempted suicide, and nearly half have 
seriously considered suicide in the past year. This is 
staggering, and Republican attempts to deny necessary medical 
care only puts them at greater risk. We know that providing 
care decreases suicide risk. We should be supporting and 
affirming transgender young people for who they are.
    This Republican ban also restricts options and disregards 
parental rights. They are telling parents that Republican 
politicians know better than they do what is best for their 
child. And this is the height of hypocrisy from a group that 
supposedly believes in limited government.
    Not only is this ban an attack on transgender youth and 
their parents, but it is also an attack on doctors and other 
healthcare providers. It would prohibit any CHGME funding if a 
hospital or training program performs this important care. This 
would cripple the funding mechanism that trains over half of 
all pediatricians in the United States. Children's hospitals 
would be forced to make a choice between providing medically 
necessary care for their patients or foregoing Federal funding 
dedicated to the training of their residents. By attacking 
providers and their training, Republicans are trying to 
dismantle medical education research and care for all children 
and adolescents.
    So it is quite simple. Republicans should stay out of the 
doctor's office. That is what I recommend. Stay out of the 
doctor's office.
    [The prepared statement of Mr. Pallone follows:]
    [GRAPHICS NOT AVAILABLE IN TIFF FORMAT]
    
    Mr. Pallone. And with that, Mr. Chairman, I yield back
    Mr. Guthrie. The gentleman yields back. That concludes 
opening statements.
    We will now move to witnesses' statements, and I will just 
let you know, as you have--some of you have testified here 
before. You have 5 minutes. There will be a green light in 
front of you, you will see that. It will turn yellow within a 
minute, and so that is time to start wrapping up if you haven't 
moved forward--if you haven't at the time. And then when it 
turns red, the time is expired.
    So I will begin by introducing all of our witnesses, and I 
will call you on one by one to give your opening statement.
    Our witnesses today are Dr. Elizabeth--``Share-it''?
    Dr. Cherot. ``Sher-oh.''
    Mr. Guthrie. Cherot. Dr. Cherot, senior vice president and 
chief medical officer for the March of Dimes; Dr. Alexis 
Thompson, chief of the Division of Hematology and Elias 
Schwartz Endowed Chair in Hematology at the Children's Hospital 
of Philadelphia and professor of pediatrics at the University 
of Pennsylvania Perelman School of Medicine; Dr. Meredithe 
McNamara, assistant professor at the Yale School of Medicine; 
Dr. Miriam Grossman, child, adolescent, and adult psychiatrist; 
Mr. George Monahan--Manahan----
    Mr. Manahan. Manahan.
    Mr. Guthrie. Manahan, child, adolescent, and adult--excuse 
me. Parkinson's advocate and patient. And Mr. Kevin O'Connor, 
assistant to the general president for government affairs and 
political action for the National Association of Fire Fighters.
    Dr. Cherot, you are recognized for 5 minutes for your 
opening statement.

STATEMENTS OF ELIZABETH CHEROT, M.D., SENIOR VICE PRESIDENT AND 
   CHIEF MEDICAL AND HEALTH OFFICER, MARCH OF DIMES; ALEXIS 
    THOMPSON, M.D., CHIEF OF DIVISION OF HEMATOLOGY, ELIAS 
    SCHWARTZ, M.D., ENDOWED CHAIR IN HEMATOLOGY, CHILDREN'S 
 HOSPITAL OF PHILADELPHIA; MEREDITHE McNAMARA, M.D., ASSISTANT 
  PROFESSOR, YALE SCHOOL OF MEDICINE; MIRIAM GROSSMAN, M.D., 
   CHILD, ADOLESCENT, AND ADULT PSYCHIATRY; GEORGE MANAHAN, 
PARKINSON'S ADVOCATE AND PATIENT; AND KEVIN O'CONNOR, ASSISTANT 
 TO THE GENERAL PRESIDENT FOR GOVERNMENT AFFAIRS AND POLITICAL 
       ACTION, INTERNATIONAL ASSOCIATION OF FIRE FIGHTERS

              STATEMENT OF ELIZABETH CHEROT, M.D.

    Dr. Cherot. Good morning, Chairman Guthrie, Ranking Member 
Eshoo, members of the Health Subcommittee. My name is Dr. 
Elizabeth Cherot. I am senior vice president and chief medical 
and health officer at March of Dimes, the leading organization 
fighting for the health of all moms and babies. Our work today 
is more important than ever with the Nation in the midst of a 
dire maternal and infant health crisis.
    By improving the health of women before, during, and 
between pregnancies, we can improve outcomes for them and their 
infants. But we have many challenges. Recently, the CDC 
released its 2021 Maternity Mortality Rates Report, which 
showed an increase of nearly 89 percent in the maternal 
mortality rate since 2018. At the same time, the number of 
women who experienced pregnancy-related complications or severe 
maternal morbidity is increasing at a troubling rate.
    The state of infant health mirrors that of maternal health. 
While the most recent preliminary 2022 CDC data on preterm 
birth shows a 1 percent decline in preterm birth rates, 1 in 10 
babies are still born too sick and too soon. This small 
decrease, while promising, only highlights the need to redouble 
our efforts.
    What is more persistent, racial disparities exist. Black 
and Native American women are 62 percent more likely to give 
birth prematurely, and their babies have a mortality rate 
double that of the white population. Let me share one of the 
stories from my full testimony that exemplifies the experiences 
faced by mothers who deliver their babies prematurely.
    Katie Wilton of Phoenix, Arizona, began facing life-
threatening complications 22 weeks into her pregnancy when she 
began hemorrhaging. During the next 8 weeks, she suffered two 
more bleeding episodes, and at 29 weeks and 2 days, Katie found 
herself in preterm labor. When she arrived at the hospital, she 
was given treatment to slow her labor and prepare for Colette's 
early arrival.
    As Katie soon--was soon to learn, she was experiencing 
chronic placental abruption, where the placenta prematurely 
separates from the uterine wall. When Colette was born at 
exactly 30 weeks gestation, she was diagnosed with severe 
intrauterine growth restriction. She weighed only 3 pounds, 1 
ounce and measured a mere 14 inches long.
    During her 63-day stay in a neonatal intensive care unit, 
Colette was given lifesaving medication. Among them was 
surfactant therapy, a treatment to advance lung development 
which was developed by the March-of-Dimes-funded research.
    This story and hundreds of thousands of others each year 
just like it highlights the need for one of--for us to do more. 
To that end, March of Dimes supports the following legislation 
being considered by the subcommittee today: H.R. 3226, the 
PREEMIE Reauthorization Act of 2023, which represents the 
Federal Government's commitment to preventing preterm birth and 
its consequences.
    This legislation specifically reauthorizes CDC's highly 
successful Pregnancy Risk Assessment Monitoring System, or 
PRAMS. PRAMS collects site-specific, population-based data in 
50 jurisdictions tracking maternal attitudes and experiences 
before, during, and shortly after pregnancy. The Act also 
reauthorizes the Health Resources Services Administration's, 
HRSA's, activities aimed at promoting healthy pregnancies and 
preventing preterm birth, and it provides a new study by the 
National Academies of Sciences, Engineering, and Medicine, 
which will examine the societal costs, the impact of societal 
factors, and gaps in public health programs related to preterm 
birth.
    March of Dimes also supports H.R. 3838, the Preventing 
Maternal Deaths Reauthorization Act of 2023, which strengthens 
and expands Federal support for the Maternal Mortality Review 
Committees, MMRCs, established under the authorizing law 
enacted in 2018. MMRCs play an invaluable role in identifying 
maternal deaths, analyzing the factors that contributed to 
maternal deaths, and translating the lessons learned into 
policy.
    They have relieved the cardiac--revealed that cardiac-
related issues are the leading cause of deaths for mothers and 
that the majority of deaths do not occur during childbirth but 
in days and weeks after. This legislation would continue to 
disseminate best practices and help MMRCs promote the case 
review process.
    Thank you for focusing your attention on these two public 
health crises. March of Dimes stands ready to work with you to 
enact this critical legislation.
    [The prepared statement of Dr. Cherot follows:]
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    Mr. Guthrie. Thank you for your testimony. The Chair now 
recognizes Dr. Thompson for 5 minutes for her opening 
statement.

               STATEMENT OF ALEXIS THOMPSON, M.D.

    Dr. Thompson. Chairman Guthrie, Ranking Member Eshoo, and 
the distinguished members of the committee, thank you for the 
opportunity to participate in this hearing to discuss H.R. 
3884, the Sickle Cell Disease and Other Heritable Blood 
Disorders Research, Surveillance, Prevention, and Treatment Act 
of 2023, and the importance of this reauthorization to Federal 
efforts to improve the lives of the nearly 100,000 Americans 
living with sickle cell disease.
    This legislation is critical to support access to care for 
patients with sickle cell and related disorders. With early 
diagnosis, we have achieved--which is often achieved through 
universal newborn screening in this country, effective 
evidence-based interventions can be introduced that will save 
lives and reduce suffering.
    My name is Dr. Alexis Thompson. I am the chief of the 
Division of Hematology and the Schwartz Endowed Chair in 
Hematology at the Children's Hospital of Philadelphia and 
professor of pediatrics at the University of Pennsylvania 
Perelman School of Medicine. In these roles, I treat children 
and adults with sickle cell disease, I educate future 
clinicians for--about sickle cell disease and comprehensive 
care, and I lead a research team engaged in innovations in 
sickle cell and other blood disorders, such as gene therapy, as 
potential cures.
    I have also served as president of the American Society of 
Hematology, which is the largest professional society serving 
both clinicians and scientists who are working to conquer blood 
disorders.
    Since the initial authorization of the Sickle Cell Disease 
Treatment Demonstration Program, HRSA has provided important 
resources for education and training to care--to provide--
approve access of quality care for patients living with sickle 
cell disease and also those with sickle cell trait. This 
program addresses an important recommendation that comes from 
the National Academy of Sciences, Education--Engineering, and 
Medicine Report addressing sickle cell disease and strategic 
plan and blueprint for action.
    H.R. 3884 will authorize the sickle cell demonstration 
programs through fiscal year 2028 and will allow the agency to 
build upon its efforts and the investment that has been made 
thus far. This program will increase the number of clinicians 
who are knowledgeable about sickle cell disease care, improve 
quality of care provided for individuals, improve care 
coordination, and to disseminate best practices for the 
coordination of services particularly during the critical 
pediatric to adult transition. This particular program is 
designed to be a regional approach and currently now covers the 
entire United States.
    One example of how this program is effectives is its use of 
the Project ECHO model, which allows providers to have 
increased confidence in treating sickle cell patients by being 
able to interface with experts in sickle cell disease, many of 
whom live--are located some geographic distance from their 
practices. By establishing a regional sickle cell disease 
infrastructure, the program partners with States to develop and 
support comprehensive sickle cell care programs that deliver 
care across the lifespan and implements telemedicine or 
telehealth technologies in order to do so. It covers the entire 
country, and it utilizes a regional hub-and-spoke model, and 
this has been particularly successful in the current funding 
cycle, particularly when individual providers are some distance 
from academic medical centers.
    I also urge--in addition to H.R. 3884, I urge the committee 
to consider how to improve the program, in particular providing 
more resources for measurement or metrics. We know that 
measurement is critical to understand the--and to quantify 
increases in certain sickle cell complications, which frankly 
are preventable with comprehensive care, and in addition will 
allow us to expand and to identify unaffiliated patients, 
patients who truly are receiving inadequate and, to the best of 
our knowledge in some cases, no care.
    We would also encourage Congress to invest further in the 
CDC's Sickle Cell Disease Data Collection Program, which 
complements the HRSA effort by utilizing its strengths and 
surveillance to be able to provide necessary information 
metrics to help us to understand where sickle cell patients 
live, their current quality of life, and how we can continue to 
intervene. There are currently only 11 States who are currently 
participating in this program. It only represents about 35 
percent of sickle cell patients. We think that there also needs 
to be continued congressional support for this vital program.
    We also--would also encourage the committee to consider 
supporting H.R. 1672, the Sickle Cell Disease Comprehensive 
Care Act, which would direct the Centers for Medicare & 
Medicaid Services to provide funds to create demonstration 
programs to look at access to comprehensive care and high-
quality outpatient care for individuals who are enrolled in 
Medicaid. We believe that these are key Federal investments for 
improving the health of individuals with sickle cell.
    The sickle cell community is deeply appreciative of this 
committee and the Congress for their ongoing commitment to 
address sickle cell through these programs. Again, I urge this 
committee to act now and to reauthorize H.R. 3884. Thank you 
for the opportunity to testify before you.
    [The prepared statement of Dr. Thompson follows:]
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    Mr. Guthrie. Thank you for your testimony. The Chair now 
recognizes Dr. McNamara for 5 minutes for your opening 
statement.

             STATEMENT OF MEREDITHE McNAMARA, M.D.

    Dr. McNamara. Thank you, Health Committee--excuse me. Thank 
you, Health Subcommittee Chair Guthrie, Ranking Member Eshoo, 
and members of the subcommittee. I am a board-certified 
pediatrician and a specialist in adolescent and young adult 
health. I have spent 12 years in medical training, in direct 
patient care, and in clinical research. I am honored to serve 
the diverse needs of young adults age 12 to 25. And as an 
assistant professor at the Yale School of Medicine, I teach 
medical residents, students, and fellows.
    I am also the cofounder of the Integrity Project for Child 
and Adolescent Health, which seeks to infuse health policy 
debate with scientific evidence. My testimony today reflects my 
academic and clinical work as well as medical consensus and not 
the views of my employer.
    The amendment to the Public Service Act before you proposes 
to defund pediatrics training programs throughout our country 
if these institutions provide the standard of care to 
transgender youth. I am honored to speak here today on behalf 
of esteemed colleagues throughout the Nation who provide this 
best-practice medical care for children and youth, including 
trans youth, and their families. As a physician with a 
commitment to patient care, I am honored to be able to do more 
for them here than I can do in the office.
    The past few years mark a rapidly shifting and hostile 
political climate towards medical care for transgender people, 
with a harsh focus on youth. Care that should be a private 
matter for families, patients, and providers is now being 
directed by legislators based on unsupported fears and 
misinformation.
    I understand that this care may be confusing to those who 
are not medical providers with expertise in treating this 
population or those who do not have a personal connection to a 
transgender person. That is why it is critical that this body 
base its decisions on facts and accurate information. Most of 
us here would not disagree with that.
    From my position as a medical practitioner and a member of 
a large community of experts in this care, I see five 
categories of misinformation: denial of the medical condition 
of gender dysphoria, false claims about standard practice, 
false claims about the evidence that backs care, false claims 
about the safety of treatments, and an attack on medical 
authority. And I am here to ensure that you have the facts to 
address this misinformation.
    Gender dysphoria, the longstanding and significant distress 
that many transgender people have from the incongruence between 
their gender identity and the sex they have at birth, is real. 
It is a recognized and serious medical condition. Transgender 
people of all ages exist. Their healthcare is based on 
established standards of care and clinical practice guidelines, 
which are themselves based on substantial medical research and 
evidence as well as decades of clinical practice. Based on 
these standards, youth and parents receive informed counseling 
about the risks and the benefits of specific treatments, and 
every major medical organization has endorsed this care.
    As a pediatrician, I must also address the proposed 
amendment. Pediatrics residencies and fellowships are the 
backbone of healthcare for children in this country. During the 
tripledemic of influenza, COVID-19, and respiratory syncytial 
virus, also called RSV, it was pediatrics residents and fellows 
who worked every hour of every day to help children survive 
life-threatening respiratory diseases.
    They help NICU babies get to kindergarten. They keep 
outpatient clinics flowing so that kids get routine well care. 
Residents and fellows form a pipeline of research and 
innovation that makes this country a global leader in every 
area of pediatric medical science.
    This bill would require children's hospitals to deny kids 
healthcare to maintain funding. As a practical matter, there is 
no way to banish all transgender youth from children's 
hospitals, nor is there a way for pediatricians to simply 
refuse to provide these youth with medically necessary care. 
All kids suffer when their legislators remove parents' rights 
and prevent pediatricians from providing the standard of care. 
And I have to tell you, American pediatricians will not accept 
being told that they have to leave even a single child behind. 
There is no room for clinic--there is no room in our clinics 
for the Government.
    I had a conversation with a trans teen recently. Gender 
dysphoria began early in puberty and worsened as puberty 
progressed. The parents sought and received help. This family 
asked me to tell members of this committee that gender-
affirming care gave their kid confidence. This teen stands 
tall, debates international law in model UN sessions, recently 
in this city, our Capitol, to compete in nationals. This care 
was lifesaving and life-affirming. College options are limited 
to States that protect trans healthcare, but even still, this 
teen is excited for the future that lies ahead.
    That is what every kid in this country deserves. Please 
don't make it harder for us pediatricians to get them there.
    [The prepared statement of Dr. McNamara follows:]
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    Mr. Guthrie. Thank you. Thank you for your testimony. The 
Chair now recognizes Dr. Grossman for 5 minutes for your 
opening statement.

               STATEMENT OF MIRIAM GROSSMAN, M.D.

    Dr. Grossman. Thank you, Chairman Guthrie and members of 
the subcommittee. Thank you for the opportunity to address you.
    My name is Miriam Grossman. I am a board-certified child, 
adolescent, and adult psychiatrist, author, and senior fellow 
at Do No Harm. I have been taking care of patients for 45 
years.
    I am going to use my time to respond to Dr. McNamara. 
First, I am struck by her use of the phrase ``sex assigned at 
birth.'' Sex is not assigned at birth. Sex is established at 
conception and it is recognized at birth, if not earlier. Dr. 
McNamara claims that her views are science-based, but to claim 
that sex is assigned at birth is without any scientific basis 
whatsoever. Its language misleads people, especially children, 
into thinking that male and female are arbitrary designations 
and can change. That is simply not true.
    Dr. McNamara claims that social and medical interventions 
are the only evidence-based treatment and that scientific 
evidence shows it is lifesaving. Without it, she is warning us 
kids will commit suicide. Well, a growing number of countries 
have effectively banned the care to which she is referring, 
and, thank God, there has been no wave of suicides or other 
mental health catastrophes.
    Three years ago, Finland placed strict limitations on 
medical interventions for minors. Sweden did the same thing 
after a 14-year-old girl was found to have osteoporosis and 
spinal fractures from puberty blockers. An investigation 
concluded, ``the risks of anti-puberty and hormone treatment 
for those under 18 currently outweigh the possible benefits.''
    The UK conducted a review and called the evidence very low. 
They have also placed severe restrictions on the care that Dr. 
McNamara calls lifesaving. Norway also analyzed the data and 
has made similar changes in policy.
    The National Academy of Medicine in France warned, ``Great 
medical caution must be taken in children and adolescents given 
the vulnerability of this population and the many undesirable, 
even serious, complications the therapies cause.'' Doctors in 
New Zealand and Australia have published similar statements.
    Is Dr. McNamara suggesting that all these countries are 
rejecting evidence-based treatment and placing their kids at 
risk of suicide? Regarding that point of view, Finland's gender 
expert, Dr. Ritta Kaltiala, said, ``It's purposeful 
disinformation, the spreading of which is irresponsible.''
    All seven countries--and Florida too, of course--concluded 
that kids don't need their development interrupted. The girls 
don't need their periods stopped and their voices lowered, and 
the boys don't need to grow breasts. What they need is 
psychotherapy.
    I have other objections to Dr. McNamara's testimony. She 
insists that her position--only hers--represents standard 
medical care. What she doesn't want you to know is that there 
is no standard. There is a debate. There is a fierce debate, 
and on the side opposite her stands such prominent figures as 
Stephen Levine, Kenneth Zuker, Paul McHugh, and James Cantor, 
among others.
    These doctors are giants in the field. They have been 
treating transgender patients and gathering data and publishing 
papers about them, and I mean no disrespect here, but since 
before Dr. McNamara was born.
    The point is that those veteran clinicians and others who 
have wisdom and experience are ignored because they disagree 
with the current narrative. They are against medical 
interventions for the same reason those seven countries are. 
There is no evidence of long-term benefit, but there is 
evidence of harm.
    I will end by quoting Jamie Reed, the courageous 
whistleblower from the Children's Gender Clinic in St. Louis. I 
believe that that hospital receives the medical education 
funding that we are discussing today. She said that doctors at 
that clinic said, ``We are building the plane while we are 
flying it.'' We are building the plane while we are flying it. 
That is how they described the treatment at their gender 
clinic. Our precious tax dollars should not support such a 
perilous experiment. Thank you.
    [The prepared statement of Dr. Grossman follows:]
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    Mr. Guthrie. Thank you for your testimony. The Chair now 
recognizes Mr. Manahan for 5 minutes for your opening 
statement.

                  STATEMENT OF GEORGE MANAHAN

    Mr. Manahan. Good morning, Chairman Guthrie, Ranking Member 
Eshoo, and members of the Subcommittee on Health. My name is 
George Manahan, and I am testifying today as a patient and 
advocate in support of H.R. 2365, or better known as the 
National Plan to End Parkinson's Act.
    I am not a policy expert like most of these people up here. 
I am a small business owner from West Virginia just trying to 
navigate the world of Parkinson's while providing jobs to 12 
full-time employees.
    Mr. Chairman, can I ask for a show of hands? I am 
interested to know how many people on the committee know 
someone personally with Parkinson's disease.
    Wow.
    I ask that question because, when I was diagnosed 13 years 
ago at age 49, I didn't know anyone with Parkinson's. It is 
great to see there is a recognition of the disease by this 
committee. For those of you who don't know someone with 
Parkinson's disease, I humbly say, you do now.
    Everyone's Parkinson's journey is different. Mine started 
with tightening of muscles in my right arm and leg followed 
with tremors. The tremors became so bad that I would hide my 
shaking arm in a pocket, the couch cushions, or anything that 
would keep my disease from becoming public, and to relieve the 
pain that I experienced.
    I was persuaded to try brain surgery known as deep brain 
stimulation. The results were incredible. My tremors were 
mostly gone, as you can see. I remember crying with my wife, 
Susan, in a doctor's parking lot after my Parkinson's 
specialist turned on my transmitter and watched my tremors fade 
away. But DBS is not a cure. It is an effective therapy for 
someone with movement issues.
    Over the years, my brain has slowed significantly, making 
it difficult for me to manage more than one task at a time. I'm 
sorry. They call it executive function, but I call it forced 
retirement. Some nights I act out in my dreams, another 
byproduct of my Parkinson's, and I feel I will someday injure 
my wife or myself. My speech has been impacted, and I am having 
some difficulty swallowing. One of the leading causes of death 
is choking on food.
    One of these symptoms by themselves wouldn't be a problem, 
but Parkinson's has a way of piling on. When I was diagnosed, I 
craved to find other people who had this disease like me, but 
in my hometown there was--they were nowhere to be found. I 
found out later that they were home suffering alone.
    So we started a 5K walk and run that blossomed into support 
groups and free exercise classes and caregiver forums and more. 
Soon we had over 200 people or more showing up to raise money, 
advocate, and learn from each other.
    A 2022 report on the economic burden on Parkinson's 
calculates the cost of PD at $52 billion. Half of that money is 
paid by the Federal Government for Medicare. The other half is 
paid by patients and families. I don't believe that those 
figures calculate the tremendous loss of income and jobs that 
families experience when someone has to stay home to care for 
their loved ones. I often worry what will be the burden just 
ahead for my wife.
    I am here today to speak in support of H.R. 2365, which is 
an important first step to relieve the economic and emotional 
burden of Parkinson's disease. The national plan is bipartisan, 
no-cost legislation that is being championed by Representative 
Bilirakis--thank you--and Representative Tonko here in the 
House and my Senator, Shelley Moore Capito, in the Senate. It 
is patterned after highly successful legislation that passed 10 
years ago for Alzheimer's disease.
    What I particularly like about this bill is that patients, 
caregivers, healthcare providers, people who are on the 
frontline of the disease, will have a seat at the table. The 
legislation will bring together the public and private sector 
to develop a national plan. The title of the bill may seem a 
little ambitious. You might ask, is it possible to end 
Parkinson's disease? I believe it is. Through research, all 
things are possible.
    We now have a biomarker that can detect Parkinson's disease 
with a high degree of accuracy. I imagine we will soon be able 
to detect Parkinson's disease long before we see the first 
symptoms. This will open up research and treatment 
opportunities that haven't previously been available.
    Mr. Chairman, Parkinson's patients throughout the country 
support H.R. 2365. Let's take this first step together to cure 
the disease.
    Thank you, sir.
    [The prepared statement of Mr. Manahan follows:]
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    Mr. Guthrie. Thank you. Thank you for your testimony.
    Mr. O'Connor, you are now recognized for 5 minutes for 
opening statement.

                  STATEMENT OF KEVIN O'CONNOR

    Mr. O'Connor. Good morning, full committee Chair Rodgers, 
Chairman Guthrie, Ranking Member Eshoo, distinguished members 
of the committee. I am Kevin O'Connor, and it is my honor to be 
here representing the International Association of Fire 
Fighters. There are 336,000 members who right now are on duty 
in each of the Nation's 435 congressional districts.
    My written testimony has been provided. Beyond the IAFF, 
all major fire service organizations, the volunteers, the 
chiefs, the Congressional Fire Service Institute, all support 
the reauthorization of the firefighter cancer registry. The 
reason is because occupational cancer is the number-one killer 
of firefighters.
    Mr. Chairman, close to your district, a 46-year-old 
battalion chief, Johnnie Jacobs, in Georgetown lost a battle 
with lung cancer. He was a nonsmoker and actually chaired the 
department's wellness program. Georgetown has since instituted 
a screening program, but it was too late for Chief Jacobs.
    Ranking Member Eshoo, 41-year-old Captain Jose Martinez 
from San Jose just passed from a rare soft-tissue cancer.
    Members of the committee, please talk to your firefighters. 
You will hear stories and anecdotes like this no matter where 
you are from.
    Before I traded in my bunker gear for a suit, I worked on 
the busiest ladder company in Baltimore County and saw my fair 
share of fires and hazmats and other incidents. As my career 
progressed, I delved into the actual statistics on firefighter 
mortality and the causes of line-of-duty deaths. I have seen 
friends die from cancer. As the local president, I consoled 
families and visited members in hospice. Then at age 52, I got 
that dreaded call that I had cancer. Thankfully, I beat it and 
am cancer-free.
    Firefighting is a filthy and dangerous job in which members 
are consistently exposed to toxins and other carcinogens. There 
are persistent inhalation risks even while wearing a breathing 
apparatus. On a wildfire, the exposure to our members is 
nonending, lasting through the entire deployment of their 
tours.
    Last week, as you may have seen, there was a large truck 
fire and bridge collapse along I-95 in Philadelphia. Those 
responders to that incident were exposed for many hours to 
billowing petroleum-based smoke along with the dust 
particulates from the collapse. This happens daily. Plastics, 
adhesives baked in flame retardants and other chemicals make 
today's smoke composition more acrid and deadly.
    Firefighters are also exposed to diesel exhaust at the 
stations where they live 56 hours a week. They sleep directly 
next to or above a garage. When an engine responds to a call, 
they pull out, leaving a diesel cloud trapped in the engine 
bay. In many stations, the bay area actually doubles as a rec 
room or training center.
    To add a little perspective, in 2020, the last year that 
statistics are available, 36 million 911 responses were 
recorded, and that doesn't include fire apparatus routinely 
leaving the station for inspections, repairs, trainings, et 
cetera. That is a lot of exposure.
    We recently uncovered data showing their bunker or turnout 
gear is laden with cancer-causing PFAS that absorbs through a 
firefighter's skin. Simply put, our own gear is killing us. 
That is unacceptable. Every firefighter needs at least one, and 
preferably two, sets of PFAS-free gear for our own health and 
safety. We get cancer earlier and die on average at rates 15 
percent greater than the general population, and more than 150 
percent above the average for really lethal cancers like 
pancreatic, lung, kidney, testicular, breast, and cervical.
    Those are the reasons why the World Health Organization 
recently named firefighting as a Group 1 carcinogen. That is 
their most deadly level. It is real, it is scientifically 
proved: Firefighting is a cause of cancer.
    The fire service does our best to police ourself. We are 
supporting early screening processes like GRAIL's Galleri test 
that can detect over 50 cancers through a simple blood draw or 
the more traditional imaging scans. Early screening saves 
lives. And I like to do a commercial for the Multi-Cancer Early 
Detection Act. It is very important that this is passed so 
these testing methodologies can be incorporated into Medicare 
and insurance programs. They save lives.
    Here is the bottom line: The--without medical data, 
researchers and epidemiologists can't uncover trends and 
specific profiles to solve this epidemic. We need to track 
cancers in the fire service, and the firefighter cancer 
registry is our best and perhaps the only chance to do so. It 
took a few years to really get the registry operational. It 
finally kicked off in April. Currently there are about 4,000 
registrants.
    Every single fire service organization is working with CDC 
to educate and register our members. If the registry is not 
authorized, we are back at square one. That can't happen. Stand 
with firefighters and pass H.R. 3821.
    I will conclude with this. From the time the registry was 
enacted until the end of last year, the IAFF had 959 line-of-
duty deaths. Six hundred thirty of those deaths, or over two-
thirds, were attributable to occupational cancer. No more needs 
to be said.
    I thank you for the opportunity and am delighted to answer 
any questions.
    [The prepared statement of Mr. O'Connor follows:]
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    Mr. Guthrie. Thank you for your testimony.
    We are now going to move into Members' questions, and we 
are going to try to stick to the 5 minutes, so please don't ask 
a question with 2 seconds left in someone's time because we 
want to give people a chance to answer the question of the 
important subjects before us today.
    So I will recognize myself for 5 minutes and begin asking 
questions.
    And to Dr. Thompson, I want to ask you questions. I have a 
good friend whose son is living with sickle cell. What is 
amazing, what happens for members of the committee, we have 
people that come--people--we had some arguments on pharma 
yesterday. Pharma, people think it is four or five big drug 
companies. It is actually a lot of innovative people out there 
trying to--small companies, a lot of them, and my good friend 
to my left's district--who are trying to solve big problems.
    And I remember Dr. Francis Collins said we can actually 
come into the forefront, we are going to cure sickle cell. And 
it is not just a chemical pill that people are going to be able 
to take. These are procedures, processes, genetics. They are 
individual medicine. And they are expensive.
    And so the Chair--the ranking member and I have worked 
together on value-based agreements within the Medicaid programs 
so the people, the most unfortunate, will have access to these 
cures.
    Would you talk about value-based agreements and why it is 
important to have--this is where State Medicaid directors can 
negotiate with drug companies. Can you imagine having a State 
government person negotiate with a drug company and not get--I 
still can't believe we don't have 435 votes in the House for 
this. But would you talk about why those are important to have 
access?
    Dr. Thompson. Certainly. And thank you for bringing this 
to--attention to the committee.
    Yes, I think that thinking about outcome-based payment 
arrangements, which are currently allowed in Medicaid, can and 
should be extended to some of these new treatment options. The 
results from the early results when things, for instance like 
gene therapy, are really incredibly exciting. And in the last 3 
years, we have seen 2 new drugs approved--3 new drugs approved 
for sickle cell disease, and we believe that there are more in 
the pipeline, based on current clinical trials.
    This is something that I think could be taken on through 
the CMMI, the Centers for Medicare & Medicaid Innovations, 
looking at improving access. And I do think that looking at 
outcomes-based in terms of whether or not people have fewer 
sickle cell complications, evidence that their sickling is now 
gone, other parameters that demonstrate durable success with 
some of these treatments----
    Mr. Guthrie. Yes, I would like to ask you another question. 
If I could move--just kind of move it just a little bit. Chair 
Eshoo and I, working together again, sent a letter to the 
Centers for Biological Evaluation and Research, a receiver at 
FDA, and it was--they responded that the--about their meetings. 
The only responses for Type B meetings almost 80 percent of the 
time.
    These are critical meetings when the FDA and regulators and 
product sponsors as manufacturers work through the approval 
process. FDA responded that 79 percent of these meetings for 
complex cell and gene therapy are without in-person meetings. 
Would you comment of the complexity of developing these 
products and why it is important that we have--the challenges 
of developing these and not having in-person meetings with FDA?
    Dr. Thompson. I can't with any tremendous detail. I 
certainly would point out, though, that it is remarkable how 
much we have accomplished in part because of the requirements 
during the pandemic that we have continued to have 
conversations as--I am at an institution where we are also 
among those who are developing some of these therapies, and 
being able to have open communications with them, whether they 
are in person or otherwise, today seems to be reasonably 
effective, and much of it has been gained by our hybrid 
meetings that have come out of the pandemic.
    Mr. Guthrie. OK, thank you. Thank you for that.
    So, Dr. Cherot, I have a cousin who is a neonatologist, and 
every time we are together--I am not a healthcare person by 
trade, so I have to pick his brain, and what is amazing is the 
development over the last decade in neonatology and how young 
these babies can live. The age of viability, if that is what 
people want to discuss, is actually pushing back further. It is 
certainly not at 39 or 40 weeks, it is at--you know, it is 
amazing what is moving forward.
    And so would you talk about to what extent the PREEMIE 
Program has contributed to these outcomes? And what is 
important for this hearing as gaps that you see and what we 
need to do better as we reauthorize the PREEMIE Program?
    Dr. Cherot. Thank you for your question. Discovery research 
is vital to expanding the quality and volume of data that we--
that is needed to address the continuing knowledge gap. There 
is no silver bullet in treatment. Preterm birth is complex. 
Fifty percent of it is--has no ideology. There's others that we 
have induced or had C-sections for babies to be delivered 
because of maternal health conditions. And then there--of 
course, there is that leakage of fluid and--amniotic fluid, and 
that also contributes.
    The financial costs of preterm birth to society, including 
long-term costs and--to society is one of the gaps that 
families in the NICUs, and post-discharge also, this would 
hopefully help us. We would also look into social factors that 
preterm birth rates need to be addressed. I would also say that 
identifying gaps in State and Federal public health programs 
that have caused increases in preterm birth as well as 
practices that have led positive impacts.
    Mr. Guthrie. Well, thank you. And I have only 4 seconds 
left. To live to what I just said, I am going to yield back, 
and I will recognize the ranking member for 5 minutes for 
questions.
    Ms. Eshoo. Thank you, Mr. Chairman. Thank you to all of the 
witnesses.
    Let me start with Dr. Cherot. Thank you for your 
leadership. As I was listening to you, I thought, Is it really 
18 years ago that we wrote this legislation? I am very proud of 
it and everyone that was a part of it. Of course, we have 
reauthorized more than once.
    Briefly, because I have more than one question to ask of 
witnesses, what do you think has been effective over the last 
15 years, and what do you think some of the causes of the 
recent surge are, and how does this reauthorization address 
those concerns?
    Dr. Cherot. So there are several factors that contributed 
to the high rate of preterm birth. Inadequate prenatal care, 
and preexisting maternal health conditions, like diabetes, 
hypertension, obesity, all contribute. I would say that 
addressing this in the future is that we are looking at 
exciting, promising research. March of Dimes contributes to 
that research, and we have prematurity research centers.
    We--actually, if you think about it, we had enhancements in 
diagnostic tests we never had before such as preeclampsia, 
which is the number-one morbidity for black women in this 
country. And those are type of the solutions that we are trying 
to research, that this PREEMIE Act will help further.
    Ms. Eshoo. Wonderful. OK. To Dr. McNamara, you just sat 
through testimony that I believe is chock full of dangerous 
misinformation and pseudoscientific ``facts,'' warped to fit, I 
think, a really outdated narrative of the trans experience in 
our healthcare system. We could spend a long time talking about 
that, but I want to give you the opportunity for a minute to 
respond.
    I have spoken to pediatric endocrinologists in my district 
who treat hormone disorders in children every day. Every day. 
And as we all go about doing whatever we are doing, this is 
taking place. This is taking place in our country. And it 
includes, which I was not aware of, early cases of--cases of 
early puberty in children as young as 2 years old. I had never 
heard of that.
    This causes, obviously, a lot of serious issues. One of the 
treatments is providing GnRH analogue therapy, a banned medical 
intervention under the legislation that is being considered 
here today. And I--again, to have, you know, 2-year-olds, 6-
year-olds, youngsters subjected to this is--well, I think you 
can hear it in my voice. I am deeply unsettled about this.
    Do you want a like 30-second response----
    Dr. McNamara. Thank you, Congresswoman.
    Ms. Eshoo [continuing]. Since I ate up some of your time?
    Dr. McNamara. Yes. So all five themes of the misinformation 
that I have identified in my work are on display. I am a 
coauthor of extensive rebuttals with science to all of them. It 
is entered into my testimony, and those documents have been 
used to successfully challenge bans on care for trans youth in 
Texas, Florida, and Alabama.
    The other testimony espouses two levels of harm: abolishing 
evidence-based care and creating a vacuum. The forced 
withdrawal of care is akin to experimentation. Dangerous, 
discredited conversion practices that attempt to convince a 
young person that they are not gay or not trans, we have moved 
on from that. Most States have banned that care in this 
country.
    It is toxic for an adult to tell an adolescent that there 
is something wrong with them. I am sure there are many parents 
in the room, and you would never want your kid to go through 
that. Suicidality is a debilitating way to endure adolescence. 
A suicide attempt is a traumatic interruption in a young 
person's life.
    Let's be clear: Pediatricians know that lifesaving means 
life-sustaining. When trans youth receive the standard of care, 
they thrive. They develop talents, they discover their 
strengths, and they get to be who they deserve to be.
    Ms. Eshoo. Thank you.
    Kevin, I wanted to know why CDC took almost 5 years to 
implement the legislation and now we are reauthorizing it, but 
I think you are going to have to maybe answer that question for 
someone else, but at least I get it on the record.
    Mr. Guthrie. OK.
    Ms. Eshoo. Thanks for being here.
    Mr. Guthrie. Yes, we will have the chance where we can do 
it----
    Ms. Eshoo. I yield back, Mr. Chairman.
    Mr. Guthrie [continuing]. Moving forward. Thank you for 
yielding back. The Chair now recognizes the Chair of the full 
committee for 5 minutes for questions.
    Mrs. Rodgers. Just to clarify, the bill does not ban 
treatment for precocious puberty, which the ranking member just 
alluded to.
    So a recent report found that the number of clinics in the 
United States focused on providing puberty blockers, hormone 
therapies, and surgeries for gender-affirming care has grown 
from just a few to more than a hundred as of February 2023. Dr. 
Grossman, in your written testimony you mentioned how certain 
European countries have decided to take a more cautious 
approach and significantly limit the use of puberty blockers 
and hormone therapies to treat gender-related conditions in 
minors. Is the United States an outlier?
    Dr. Grossman. Well, it certainly--yes, more and more 
becoming so. I just want to take one moment because this is 
really bothering me. Representative Eshoo, I am sorry if I am 
mispronouncing your name.
    Mrs. Rodgers. That is right.
    Dr. Grossman. Representative, you are very confused about 
something. When we--when----
    Mr. Guthrie. I am sorry, just--[indiscernible] suspend.
    Dr. Grossman. Yes. Representative, you--I would like to 
clarify something for you.
    Mrs. Rodgers. You can clarify it to me. Clarify it to me.
    Dr. Grossman. Yes. Precocious puberty is a medical 
condition. It is a condition in which the child had----
    Mr. Guthrie. What's that--I am sorry, would you--could you 
suspend the clock for a second?
    Ms. Eshoo. She spoke to me directly, Mr. Chairman.
    Voice. And she can't characterize how you----
    Ms. Eshoo. You can't characterize me.
    Mr. Guthrie. Yes. OK, you can't characterize the way that 
she is--her question or what she has asked, so if you would 
just respond to----
    Dr. Grossman. OK, I am----
    Mr. Guthrie [continuing]. The Chair who is asking the 
question.
    Mrs. Rodgers. Yes.
    Dr. Grossman. OK.
    Mr. Guthrie. Thank you.
    Dr. Grossman. The point is that precocious puberty, which 
we have treated with blockers for decades and is approved by 
the FDA for that use, that is a medical disorder, that is a 
disorder in which the child has abnormal hormone levels 
circulating that causes their bodies to premature enter--
prematurely enter puberty. We do not want that to happen.
    We are talking about an experimental use of these agents in 
children that are completely healthy. They have no medical 
disorder. So we are artificially blocking a biological process, 
a natural process called puberty. Puberty is not a disorder. We 
need to go through puberty in order to reach adulthood. Every 
system of the body, the brain included, needs to go through 
puberty to reach adulthood.
    And what we are doing in gender-affirming care is stopping 
that natural organic process and blocking it and then shortly 
thereafter--in most cases, over 90 percent of cases--
administering the hormones of the opposite sex so that the 
child will go through a synthetic puberty, not the organic 
puberty----
    Mrs. Rodgers. Thank you.
    Dr. Grossman [continuing]. But a synthetic puberty. OK, I 
am sorry.
    Mrs. Rodgers. Thank you.
    Dr. Grossman. You asked me about the European countries.
    Mrs. Rodgers. I asked you if the United States was an 
outlier.
    Dr. Grossman. Absolutely.
    Mrs. Rodgers. OK, thank you.
    Dr. Grossman. The United States and Canada are out----
    Mrs. Rodgers. And would you speak to what the data tells us 
about the long-term impacts of these medical interventions?
    Dr. Grossman. So that is the thing. You see, this, until 
recently, was an extremely rare condition. It was so rare that 
when I went to medical school decades ago, I never expected to 
see one case in my life. That is how rare it was. And now that 
is all I do.
    So you see, in the past 10 years or so, specifically since 
maybe 2015, there has been an explosion of cases, an absolute 
tsunami of cases, and the question is why is that. And those 
cases are very different than previous cases. This is a new 
population. The old--the prior gender dysphoric cases that we 
studied were mostly----
    Mrs. Rodgers. Thank you.
    Dr. Grossman [continuing]. Boys.
    Mrs. Rodgers. OK. Yes, thank you. I wanted to get to girls 
too, because I am--I had mentioned my concern about the mental 
health crisis for young girls. And over your career, would you 
speak to how patients experiencing gender dysphoria changed in 
the number and characteristics, and also speak to the long-term 
impacts for these medical interventions?
    Dr. Grossman. OK. So what I was--wanted to say is that, 
when we speak about long-term, we don't have the data yet 
because these are just--this is a new population called ROGD, 
rapid-onset gender dysphoria, and we are just studying them 
now. It is a new demographic. Mostly girls but lots of boys as 
well. My practice is 50 percent boys. These are kids who have a 
lot of previous mental health conditions----
    Mrs. Rodgers. OK, thank you, Dr. Grossman. Thank you. I am 
going to have to cut it off there because I heard my colleagues 
say that this should be a private decision between parents, 
teachers, and doctor--or parents, children, and doctors, that 
we should protect parent rights, and that Republicans are 
putting politics between children, parents, and the doctor.
    The truth is parents are being removed from their 
children's doctor's offices and kids are being taken from their 
parents and their homes. It is making it us versus them. That 
is my fundamental concern.
    I yield back.
    Mr. Guthrie. Thank you. The Chair yields back. The Chair 
now recognizes the ranking member of the full committee, Mr. 
Pallone, for 5 minutes for questions.
    Mr. Pallone. Thank you, Mr. Chairman.
    I have to say I am deeply disappointed in the partisan 
Children's Hospital GME legislation being considered today. It 
prescribes in very minute detail the types of care that must be 
prohibited in order to receive funding and tells our healthcare 
providers, major medical associations, and patients that 
Republican Members of Congress know better than them about what 
should be considered standards of care within our medical 
system. And that should scare us all, particularly when this 
program is designed to train the next generation of 
pediatricians and pediatric subspecialists.
    So my questions are of Dr. McNamara. I know that 
transgender people and those who advocate for the rights of 
transgender people are currently facing fear, intimidation, 
threats of violence. But I believe that we must speak out on 
their behalf and support them, and I want to say thank you to 
you today for doing so.
    Now turning to my questions. If this bill were to become 
law, what would the impact be on pediatric care?
    Dr. McNamara. So I am very privileged to sit next to two 
people who have shared details about the types of medical care 
that benefit patients who I have cared for in my career, people 
with sickle cell disease, premature babies. Many people here 
might not know what goes into that type of care, but I do. And 
it is not my specialty anymore. I have subspeciality training 
in adolescent medicine.
    But the experiences that I had in a NICU in the middle of 
the night resuscitating preterm infants, counseling their 
parents, working with my colleagues, offering advanced 
treatments for sickle cell to children with crippling pain have 
forever shaped my training. I am an excellent clinical 
researcher because of my training as well. And I think that I 
am not the only person. You know, I spoke to so many of my 
colleagues about this testimony. Everyone expressed disbelief 
and regret that it would escalate this far.
    Everybody wants children to be healthy and safe, but their 
care and what they require to be healthy and safe is expert. We 
know what we are doing. We know how to do it really well. And 
all that we ask is that we be allowed to do it without any sort 
of legal interference.
    Mr. Pallone. I appreciate that. I mean, what I am seeing 
here and in so many different forums is Republicans--Republican 
Congresspeople trying to or determined to substitute their 
opinion for experts, experts in medical fields, experts in 
agencies, and it is truly scary.
    The legislation is not only an attack on transgender youth 
and their families, but it is an attack on providers and the 
training they receive. Can you speak to how this would impact 
the training that pediatric residents receive? Briefly, because 
I have one more question.
    Dr. McNamara. Yes, of course. We are already seeing that 
less people are looking to go into pediatrics because it has 
been politicized and interfered with. There is a great deal of 
moral injury that accompanies being told what you can and can't 
do and needing to legally withhold care from people who need it 
whose lives depend on it. So I would expect not only would it 
cut off at the knees the vast majority of training for 
pediatrics residents and fellows in this country, but it would 
deter the future of pediatricians.
    Mr. Pallone. So what--you are seeming to suggest that this 
would have an impact on the pediatric workforce. Do you want to 
comment on that?
    Dr. McNamara. It would have a devastating impact on the 
pediatric workforce. People would bring sick kids into 
children's hospitals and there wouldn't be anyone there to take 
care of them.
    Mr. Pallone. Well, thank you.
    You know, Mr. Chairman, I can't understand why the majority 
has chosen to hijack this critical program to have an 
ideological battle. I just don't understand it. This committee 
has a long history of working together to solve important 
healthcare challenges, and training our healthcare workforce 
being one of the most important. It is just disappointing that 
instead of considering Representative Schrier's bill to 
reauthorize this program on a bipartisan basis as we have done 
in the past that the Republican majority has instead decided to 
jeopardize the reauthorization of the CHGME through this 
harmful and inhumane policy, and I just don't understand it.
    I urge my colleagues to strongly oppose this build--this 
bill. And I yield back, Mr. Chairman.
    Mr. Guthrie. Thank you. The ranking member yields back. The 
Chair now recognizes Dr. Burgess for 5 minutes for questions.
    Mr. Burgess. Thank you, Mr. Chairman.
    Dr. Thompson, I have worked with Representative Davis for a 
number of years on this issue that you have brought to us today 
and the reauthorization of the Sickle Cell Disease bill. 2018 
was the first reauthorization that has happened since 2004 when 
it was tacked onto a tax bill, believe it or not. So can you 
speak to why it is important that we reauthorize the bill?
    Dr. Thompson. I am happy to. And thank you so much for your 
long-term support.
    One of the important things that happened in this most 
recent cycle was the ability to expand this program so that it 
now covers all 50 States. But all of the efforts prior to that 
were focused on certain areas, and the fact--prior to this most 
recent cycle, there was a substantial region, and that is the 
U.S. Southeast, that was not included in competitive--as a 
competitive region, clearly an area where there was a high 
concentration of sickle cell patients.
    This current structure allows us not only to ensure that 
with this regional hub-and-spoke approach that we are--we have 
access in all 50 States, but they are actually now diffusing 
the expertise that occurs primarily at academic medical centers 
and ensuring that patients actually have access to physicians 
who are more knowledgeable, even if they are in primary care 
practices, even if they are in community practices, and that 
was a fundamental change----
    Mr. Burgess. Sure.
    Dr. Thompson [continuing]. For the comprehensive care that 
is dispersed, I believe, in a more equitable way.
    Mr. Burgess. And something you said during your testimony, 
there have been various FDA-approved therapies that have 
happened in the past couple of years, is that not correct?
    Dr. Thompson. That is absolutely correct, yes.
    Mr. Burgess. And we sat in this same hearing in 2016, the 
sickle cell disease advocate was at the table where you are. I 
can't say that I was paying complete attention, but she made 
the statement, it has been 40 years since there was an FDA-
approved treatment for sickle cell. It really--I mean, it 
jarred me because 40 years took me back. I was an intern at 
Parkland Hospital taking care of sickle cell patients in the 
emergency room. So in that 40-year timespan, we hadn't helped.
    I know the things that Representative Guthrie is talking 
about in his value-based care that he offered in a different 
bill that we heard in a markup, and it is expensive, and we 
have to pay attention to that. But is there any way to estimate 
what was the cost of doing nothing for 40 years?
    Voice. Oh, I forgot to do this.
    Dr. Thompson. I think that is a very difficult equation. 
You are absolutely right. But having said that, even in that 40 
years when we just had one drug, that drug was hydroxyurea, a 
repurposed chemotherapeutic agent. And I daresay that since it 
was originally approved in the late 1990s, we really have seen 
repeated clinical trials, many of which were federally funded, 
that continue to demonstrate its effectiveness, and it is not 
expensive.
    Having said that, it is currently one of the many drugs 
that we currently are experiencing in shortages in this 
country.
    Mr. Burgess. I see.
    Dr. Thompson. And so certainly we have multiple problems. 
We have a limited number of drugs, and then even some drugs 
that clearly will work, we currently are experiencing a 
shortage. We also still have providers who are unaware that 
there are any treatments available for sickle cell disease, and 
so we think that there are opportunities to utilize things----
    Mr. Burgess. True.
    Dr. Thompson [continuing]. Like the HRSA program to 
disseminate that kind of education and training.
    Mr. Burgess. That is absolutely critical.
    Dr. Cherot, let me just ask you a couple of questions on 
both the PREEMIE Act and the Preventing Mental Deaths Act. On 
the Preventing Maternal Deaths reauthorization, you kind of 
answered this question for Representative Eshoo, but can you 
just speak to the fact that it is important to reauthorize to 
build on the work that has happened before?
    Dr. Cherot. Absolutely, yes. First and foremost, thank you, 
and thank you for your story of your daughter. The PREEMIE Act 
helps shrink our knowledge gap, I should say, and closes that 
gap around the data that we need to continue to fill in to be 
able to do that research. We need the--CDC's PRAMS Program is 
one such highly effective tool that has allowed us to better 
understand trends, risks, and other factors impacting pregnant 
and lactating people, and that alone is in this.
    Mr. Burgess. So--and this will help providers, right, 
taking care of those very premature infants?
    Dr. Cherot. Absolutely. We talked about neonatal intensive 
care unit that at--who are at the bedside who need better data. 
I think about the 30 years I have been delivering babies. The 
surfactant was a huge impact helping lung expansion. Getting 
more research and solutions to help preemies is where--the aim 
of this.
    Mr. Burgess. Very good. Thank you, Mr. Chairman, I will 
yield back.
    Mr. Guthrie. The gentleman yields back. The Chair 
recognizes Mr. Sarbanes for 5 minutes for questions.
    Mr. Sarbanes. Thanks very much, Mr. Chairman. As this 
hearing makes clear, Congress must authorize this year several 
healthcare programs to continue critical data collection, 
research, treatment efforts that promote better access to care 
and cures for millions of Americans. One of those, as we have 
heard, is the National Firefighter Cancer Registry, which seeks 
to improve data collection to better target efforts to address 
cancer prevalence among firefighters. It is a vitally important 
effort because these selfless first responders are often 
exposed to PFAS, as we heard, and other toxins daily as they 
protect our community.
    Mr. O'Connor, first, thanks for your lifetime of service, 
thanks for your service to the citizens of Baltimore County, 
which I am very familiar with. Given the high-risk exposures 
that firefighters face, explain again the importance of the 
registry, and then in particular the actions the fire service 
and local governments are taking to ensure that their 
firefighters are getting the requisite screenings, if you 
would?
    Mr. O'Connor. Thank you, Congressman. The fire service 
traditionally has not been awash in good data. In fact, quite 
frankly, the data that we have is terrible. That is partially 
responsible for the fact that it is a local function of 
government, so there has never been a repository for anything 
really in the fire service. And as medical science and research 
has proven the occupational risk of cancer, we have never been 
able to get a handle on the overall number of firefighters who 
have cancer, where they are located, what specific exposures 
are the cause, the frequencies of the cancers, many of which 
are very, very anomalous, they are not the normal prostate, 
they are very strange cancers.
    What proves that more than anything else is the aftermath 
of 911. We lost 343 firefighters that day during the collapse, 
but since then there's been over 1,100 who have died from 
various respiratory and cancer illnesses, and they are just 
very strange illnesses. So we are trying to get a handle on 
that.
    So the registry, when it was originally conceived, it is 
voluntary, but to try to actually get a full accounting of all 
the firefighters, career and volunteer, we encourage people to 
register, whether or not they have been afflicted with cancer, 
so that we develop a baseline for future studies.
    In our view, the best mechanism to try to deal with this is 
through early screening. And regrettably, there is no mechanism 
to do that. In our State of Maryland, the Professional 
Firefighters of Maryland, the local that you represent in Anne 
Arundel County, Howard County, Annapolis, the airport, their 
members self-pay essentially to have screenings, cancer 
screenings. The jurisdictions don't provide it.
    That is a real problem because we know that if we get 
firefighters early, they are detecting stage 1 pancreatic 
cancers, for example. That is treatable. When it gets beyond 
that, it is a death sentence.
    So our two challenges are, one, making sure that we have 
adequate data and making sure that our members have access to 
that type of testing. What would be ideal, quite honestly, if 
HHS followed the World Health Organization and essentially 
recognized firefighting as a high-risk profession so that 
insurance coverages would take care of these testings and our 
people wouldn't have to self-pay.
    Mr. Sarbanes. Thank you very much, I appreciate it.
    Let me switch gears quickly. One of the benefits of this 
graduate medical education program that we have been taking 
about with Children's Hospital is that it contends with two 
significant and intersecting challenges, one being the 
children's mental health crisis and the other being healthcare 
workforce shortages at every level of care. And this program 
holds a unique opportunity to help us address both 
simultaneously.
    Dr. McNamara, as a pediatrician, medical professor, can you 
speak to the importance of a strong GME program for children's 
hospitals on our ability to strengthen an expand the pipeline 
of both mental and physical health providers we need both now 
and into the future?
    Dr. McNamara. Thank you very much. Sorry about that.
    We are very good at what we do in supporting young people 
in navigating this new mental health crisis. We cannot do with 
less resources. It is simply not tenable.
    We do need more, but we are training ourselves in how to 
provide excellent mental healthcare by consulting with other 
experts. The guidelines are improving in order to kind of 
address the crisis that you have alluded to. If we are less 
supported, there will be nothing that we can do, and I just 
have to make that abundantly clear. We cannot make do with 
less.
    Mr. Sarbanes. I appreciate that very much, and it is 
unfortunate that there is this effort to undermine the program 
when it can protect the health and wellness of every single 
child and adolescent. That concern, that focus is too important 
for partisan politics, so I urge the committee to take that 
responsibility seriously. Let's pass a clean reauthorization 
bill. And I yield back.
    Mr. Bucshon [presiding]. The gentleman yields back. I now 
recognize Mr. Latta for his 5 minutes.
    Mr. Latta. Thank you, Mr. Chairman, and thanks to our 
witnesses for being here today.
    And, Mr. O'Connor, if I could start my questions with you. 
First, thanks for your service out there. You know, when I--in 
fact, last night about 9:00, right across from this building 
there was a ladder truck, another fire--a pumper truck, and an 
ambulance right here on campus. And so we all know that our 
firefighters and our first responders are there 24/7 for us, 
and so we thank you for it.
    One of the things I would like to maybe check--talk to you 
a little bit about, because I know you were talking about the 
registry and the baseline and the screening. You talked a 
little bit earlier because, again, when I look at my district, 
the vast majority is volunteer. And so, you know, when you are 
talking about volunteers, first of all, I go to so many fish 
fries, pancake days, barbecues to try to help support. But 
there is no way we can keep up with it for them because, again, 
in talking with our chiefs out there and other firemen and 
firefighters, you are looking at probably 11 to 13,000 thousand 
dollars to equip a person just, you know, a fireman--a 
firefighter out there right now, and so it is pretty expensive.
    But, you know, when you are talking about with the registry 
and the baseline and the screening, can--how do we work with 
our volunteers out there, because first of all, with 70 percent 
of the country at volunteers, and we are--we have seen 
volunteers--unfortunately, we are losing folks that they just 
aren't volunteering like they used to. What--how do we help 
there?
    Mr. O'Connor. Well, first, thank you for recognizing the 
difference between a ladder truck and a pumper. A lot of people 
don't make that distinction.
    I don't presume to speak for the National Volunteer Fire 
Council, but I will say this: Under the leadership of our newg 
general president, Ed Kelly, for the very first time in 
history, our organization sat down with the leadership of the 
NVFC, and we are trying to forge a path together to help 
volunteers with retention and recruitment and making sure that, 
for a lot of our members, the mandatory overtimes and the 
staffing shortages are abated.
    So I share your overall concern with the volunteer fire 
service. They provide an invaluable service to the community 
which they serve, and the dedication of providers is really 
unmatched.
    With respect to the actual cancer registry and how we 
address that, it is more of a challenge. What we are trying to 
do on the career side, in departments large and small--and 
there is a misconception, too, with the IAFF. Most of our 
locals are under 30 members. Yes, we represent New York and the 
big locals, but throughout Ohio we have 285 affiliates in a lot 
of small towns, so we face the same challenges. But, of course, 
on a volunteer basis, they are not employees.
    So we are trying to figure out a way to create incentives 
that the people register because their risks are no less than 
the risks that our people face. So in terms of your larger 
question, you know, it really needs to be an overall effort.
    I also want to credit the U.S. Fire Administrator, Dr. Lori 
Moore. We had a summit--the first summit in like 50 years of 
all the fire service organizations up at Emmittsburg, and we 
came out with one theme, and it is one voice fire service. And 
I can assure you the partnership between the organizations and 
the providers at the local level is very strong.
    Mr. Latta. Oh, thank you.
    Mr. Manahan, if I could switch real quick to talk to--about 
your very--your testimony is so powerful. You know, I--
hopefully we will have a cure in the future, but, you know, 
some of the statistics out there, you know, in your testimony 
that 1.2 million people in the United States struggle with 
Parkinson's today, and it is expected to double by 2040.
    Mr. Manahan. Yes, sir.
    Mr. Latta. Could you--and I know I only have about a minute 
left, but could you maybe go into that? Why are we going to see 
a doubling of the numbers in Parkinson's, and what we can do?
    Mr. Manahan. Well, I think there are several factors. Let 
me give all the statistics first real quick, and then I will 
address your question. There's over a million people with 
Parkinson's. Fifty percent--I am sorry, 90,000 new people get 
diagnosed every year, and that is 50 percent higher than they 
first originally thought. Well, we are getting a lot of 
firefighters who are also getting Parkinson's disease.
    It is the fastest-growing neurological disease in the 
country. The number of people with Parkinson's, as you had 
mentioned, is supposed to double by 2040. Chemicals are playing 
a role in that. I--you know, I think chemicals in firefighting, 
obviously, but there's a lot of chemicals that people have been 
exposed to early on in their years and as they grow older they 
get Parkinson's disease, and they make themselves more 
susceptible to Parkinson's disease.
    But I--you know, I think without a congressional mandate, 
we may be waiting for a cure for many years down the road. I 
think we have the time right now to do something really, really 
great for people with Parkinson's.
    Mr. Latta. Thank you.
    Mr. Chairman, my time is expired, and I yield back.
    Mr. Bucshon. The gentleman yields back. I now recognize Mr. 
Cardenas from California for his 5 minutes.
    Mr. Cardenas. Thank you, Chair Guthrie. I appreciate this 
opportunity for us to have this hearing. Really pleased to see 
some of the bipartisan bills that we have been working on that 
we will be discussing here in this committee. But at the same 
time, I am deeply disappointed in the partisan Children's 
Hospital GME proposal put forth by my Republican colleagues.
    There is bipartisanship. However, clean reauthorization 
that easily could have been noticed by my Republican colleagues 
just had to take--they just had to take another punch at young 
people, trans kids. These children, human beings just like you 
and me, who have done no wrong, no harm to anybody else, but 
just want to live their lives in truth. It is unfortunate that 
this bill is here before us. Welcome, everybody, to Pride 
Month.
    This Republican majority has gone out of its way not only 
to demonize access to care for trans children but to cut off 
access to Children's Hospital GME resources for any provider of 
those services. Why? Why is it so critical that you control the 
medical decisions of other people's kids and of those kids' 
doctors? I am once again shocked by the party of limited 
government's stunning overreach into these private medical 
decisions.
    Now let's look at the numbers. In 2022, nearly one in five 
transgender kids attempted suicide. Of trans children who 
received gender-affirming care, there were 60 percent lower 
odds of depression and 73 percent lower odds of self-harm or 
suicide thoughts. That is, in fact, life saving. There has been 
real honest bipartisan agreement in this committee on the need 
to improve youth mental health, yet now we are further 
attacking these kids' access to care, degrading their mental 
health in the process, and pouring gas on the fire.
    You want to protect kids? All kids? Well, gender-affirming 
care seems to have lifesaving, positive impacts on the mental 
health of trans youth. So this isn't about protecting American 
kids at all. And that is what is worse. You are pulling this 
political stunt when we know that one of the greatest threats 
to our healthcare ecosystem is workforce shortages. It is 
shameful that Republicans are holding pediatric care resources 
hostage to score political points at the expense of already 
vulnerable trans children, young human beings.
    The price of admission to practice pediatric medicine 
cannot and should not be discriminated against, especially when 
it comes to children.
    Dr. McNamara, in your experience, when patients have access 
to gender-affirming care and can exist in gender-affirming 
environments, in what ways does this improve adolescent 
outcomes?
    Dr. McNamara. Thank you, Congressman Cardenas, for this 
question. We have spent a lot of time talking about how 
vulnerable transgender youth are, but I would like to take a 
moment to talk about how privileged I am to be able to care for 
them and how privileged I am to be part of a larger medical 
community that does.
    When transgender youth have unrestricted access to an 
affirming social environment and to medical treatments that 
they qualify for and that they desire and that their parents 
consent to, they thrive. Now what does it mean for an 
adolescent to thrive? It means that they are not their gender 
identity solely. It means that they develop their talents, they 
get really good at the piano, they learn how to ice skate, they 
get scholarships to college, they become productive members of 
our community who will make us stronger for years to come.
    In my clinical experience, I have seen this happen in a 
myriad of ways, and it is often that triangle of patient-
parent-provider support that makes it happen. There is no room 
in there for anything else.
    Mr. Cardenas. Thank you. We have limited time for our 
questioning, but I just wanted to say thank you so much for 
putting your heart and soul into every single one of your 
patients and treating every single one like a deserved human 
being. You say that you are privileged to have them and care 
for them. They are privileged to have you truly, truly care for 
them, to see them, to love them, and to give your heart and 
soul to your work and to them and their lives. Thank you very 
much.
    My time has been expired. I yield back.
    Mr. Bucshon. The gentleman yields back. Mr. Griffith is now 
recognized for 5 minutes for his line of questioning.
    Mr. Griffith. Thank you very much, Mr. Chairman.
    Mr. O'Connor, can you elaborate on some of the work being 
done to help lower PFAS toxins in firefighter gear that would 
make it more resistant to both the PFAS and maybe help 
firefighters as well?
    Mr. O'Connor. We are--technology is trying to catch up to 
this issue, and I am certain that Representative Dingell will 
probably bring it up. I know that she and Chairman Graves from 
the Transportation Committee are working on a bill that will 
soon be introduced on that issue.
    The first thing that really needs to be done is more 
testing. It is very, very abundantly clear that this exists in 
a vapor barrier. The history behind it is most firefighting 
gear, apparatus training, et cetera is established by standards 
promulgated by the National Fire Protection Association. They 
have a standard, without getting into all the details, that 
essentially a composite turnout--a piece of turnout clothing 
has three layers: an outer layer, an inner layer that is a 
moisture barrier, and a layer beyond that.
    The moisture barrier is the area in which the PFAS is. And 
quite honestly, the way the standards were promulgated, only 
gear that had PFAS in it would be able to meet the standard. It 
is an ultraviolet light standard, which intuitively makes no 
sense because it is the middle layer of a garment. Its 
opportunity to see ultraviolet light is basically nonexistent. 
And this has created the problem.
    So there's various enterprises looking, studying it. The 
University of Notre Dame was the first one that really brought 
it up. I can't think of the researcher's name, but I will get 
you the information on some of the definitive evidence with 
respect to it.
    But there are people looking at it now, and I know there is 
going to be a field test that is going to begin in Metro--West 
Metro, Colorado. Chief Don Lombardi is partnered with his local 
affiliate there, and they are putting a first set of supposedly 
non-PFAS gear into the field. It is a major issue. I am not the 
safety and health issue expert in our organization, but it is 
our number-one issue in the fire service addressing the status 
of our gear.
    Mr. Griffith. So here is one of the things I love about 
these hearings, and I know sometimes people think why am I 
here--people are moving in and out, and we have two hearings 
going on right now, and some people have other committees--but 
it raises questions in your mind.
    So I toured a number of years ago a facility in Pembroke, 
Virginia, that is Giles County, a few miles outside of the area 
where Blacksburg is, i.e., Virginia Tech. They have a product 
or they have a company out there called NanoSonic. They 
actually make fire gloves. So I called them--had my team call 
them while I was in here listening to the testimony.
    They don't use PFAS. And it is basically a fabric with a 
glass, and I am going to get it all wrong, but it was really 
interesting. It is glass inside that creates your barrier to 
temperatures. I mean, I have had my hand in one of their gloves 
over an acetylene torch. Nothing.
    Now you can only use it once because once it is heated, the 
glass transforms and will no longer provide the protection. But 
it provides that protection while the firefighter is wearing it 
and there's no PFAS. So add that to your list. NanoSonic out of 
Giles County, Virginia.
    Mr. O'Connor. If I can just comment.
    Mr. Griffith. Yes.
    Mr. O'Connor. I will make sure that our safety and health 
people reach out to them. But as a W&L guy, I know a lot of 
good things come from the Shenandoah Valley.
    Mr. Griffith. There you go.
    Mr. O'Connor. So thank you very much.
    Mr. Griffith. There you go. Yes, and I was W&L Law, just so 
you know. Yes, that's good.
    Voice. Go Generals.
    Mr. Griffith. Let's talk about the cancer registry itself. 
So you want folks to sign up for it. Is that before they have a 
cancer, you want everybody to sign up for it, and how does it 
work, and then how does it identify what the cancers are, and 
can it eliminate--or can it maybe focus in on some of the 
substances that are causing these cancers?
    Mr. O'Connor. What I alluded to in my oral testimony----
    Mr. Griffith. Yes.
    Mr. O'Connor [continuing]. Is it really just started in 
April. And part of the reason--to answer, I know she's no 
longer in the room, but the ranking member's question----
    Mr. Griffith. Yes.
    Mr. O'Connor [continuing]. Is it was a combination from 
what we have been told--we are obviously sorely disappointed 
that it has taken this long, but a combination of COVID and 
some cyber issues related to protecting people's personal 
health information.
    Mr. Griffith. Right. Yes.
    Mr. O'Connor. So that is what the delay was. And, again, 
right now we only have 4,000 people. We want everybody to sign 
up because the key is a baseline.
    Mr. Griffith. Yes.
    Mr. O'Connor. When people are hired into the fire service, 
there's fitness requirements. So generally people coming in are 
a heck of a lot healthier than the general population. That is 
the one of the reasons that local governments always want 
firefighters included in their medical plans because we bring 
down the risk.
    Mr. Griffith. Right.
    Mr. O'Connor. As the exposures occur over the years, that 
is when the cancers develop. So what we need is for the kid 
that comes into the fire academy or to volunteer, test him 
immediately----
    Mr. Griffith. You want to follow him all the way through.
    Mr. O'Connor [continuing]. And follow him through to----
    Mr. Griffith. I am running out of time. I want to ask one 
more question. It is not because I am against it, I am just 
curious because I am going to have to defend it with some of my 
friends. The number in the bill is almost double what it was 
previously. Can you tell me quickly why the reason for that is?
    Mr. O'Connor. The technology, trying to trace some of it.
    Mr. Griffith. OK.
    Mr. O'Connor. And, again, I think it is--in the scheme of 
things, it is a very modest----
    Mr. Griffith. It is 5.5 million overall.
    Mr. O'Connor. Right, right.
    Mr. Griffith. That is after it has been doubled.
    Mr. O'Connor. Yes, sir.
    Mr. Griffith. All right, I yield back.
    Mr. Bucshon. The gentleman yields back. I now recognize 
Mrs. Dingell from Michigan for her line of questioning.
    Mrs. Dingell. Thank you, Mr. Chairman.
    I want to thank all of the witnesses for being here today 
because you each have a very personal story, and it is--we 
understand it, and it is hard, and quite frankly, I have been 
on the board, I have worked with almost all of your 
organizations, and members have personal stories here. So I 
want to just thank you for that and sharing that with us.
    My late husband used to say that our children are 25 
percent of our population and a hundred percent of our future. 
And I know that it is really important that we make sure that 
we have got all the tools and resources to make sure that all 
of our children live and grow and thrive, and that should be 
one of our top priorities. So I do have to make a point before 
I get to my other questions, that I am concerned about the 
dangerous impact of the current bill we are considering on 
reauthorizing the Children's Hospital Graduate Medical 
Education Program, because I think we are putting politics into 
deeply personal healthcare decisions.
    The CHGME Program extends far beyond transgender youth. It 
provides vital Federal support for children's hospitals across 
the Nation. The program trains 56 percent of all general 
pediatric residents. Its importance in training the workforce 
that keeps our children healthy and safe cannot be overstated.
    But this bill would not only prohibit funding for gender-
affirming care, but it withholds funds from any hospital 
providing it. Just in my State, the Children's Hospital in 
Detroit and the University of Michigan treat anybody who comes 
through its doors. These are mental health issues, and we 
really need to understand what we are doing here, and I think 
it is unacceptable.
    But I want to turn my attention to the bill that deserves 
our full support. It is bipartisan. The Gabriella Miller Kids 
First Research Act 2.0, which we authorize an increased funding 
for pediatric care research.
    I was glad to introduce this lifesaving bill alongside 
Representative Wexton, Cole, and Bilirakis. For those who don't 
know, DIPG is a devastating pediatric brain tumor. It is almost 
always fatal, and the average overall survival for children 
diagnosed is less than 1 year. The bill is named after 
Gabrielle Miller, a childhood cancer advocate who lost her 
battle with DIPG when she was 10 years old.
    But I have had the sadness, unfortunately, of working 
closely with children and families struggling with the horrors 
of DIPG, like the Carr family. Jason--or, Jason is the father. 
Chad Carr. I lived with him from the time that he was diagnosed 
until he died at age 5. And Jack Demeter, a young boy who lost 
his battle with DIPG at the age of 3. Watching someone live 
with cancer at any age is hard, but it is gut wrenching when 
you are watching a child.
    So, Dr. Thompson, I know you are here to discuss sickle 
cell disease, but within your capacity as chief of the Division 
of Hematology at Children's Hospital of Philadelphia, you are 
also a professor of pediatrics. Could you talk about or do you 
agree that more robust funding for pediatric cancer will help 
find new treatments and cures for young patients, and can you 
also--because I am not going to have a lot of time and I got to 
get one firefighter question in--talk about why childhood 
cancer differs from adults?
    Dr. Thompson. I will do my best. But certainly there are 
many childhood cancers that are completely unique. They are not 
ones that occur at an early stage in children. Some of them 
actually occur only in children. We have made some remarkable 
advances in pediatric care, such that 80 percent of children, 
because of research, are surviving. DIPGs--children with DIPGs, 
unfortunately, are not in that group. We are lucky if they 
survive 1 year.
    These are the opportunities for research, and many of our 
children's hospitals are also some of our most important sites 
for pediatric research. Pediatric research only makes up about 
10 percent of the NIH's budget, but what we do with that is 
remarkable, and so certainly we look for it to be funded by 
nonprofits, by private-public partnerships, as well as other 
governmental agencies.
    But we can't underscore the number of advances that we have 
made in pediatric care that have largely come from evidence 
basis, and those are from research.
    Mrs. Dingell. Thank you. OK, 20 seconds left.
    Mr. O'Connor, we--I have highlighted, and I want to thank 
my colleague who really asked the questions that I was going to 
ask, and I hope--Mr. Graves has been busy, so we are hoping to 
get our bill, and we hope you will join us.
    But is there anything that--you have highlighted the 
importance of it and the danger. Is there anything you want to 
add in 3 seconds?
    Mr. O'Connor. [Laughter.] Just that it needs to get done. 
Our lives are at stake. And we thank everybody for their 
leadership and support of it.
    Mrs. Dingell. Thank you for all our firefighters do.
    I yield back, Mr. Chair.
    Mr. Bucshon. The gentlelady yields back. I now recognize 
Mr. Bilirakis for his 5 minutes.
    Mr. Bilirakis. Thank you. And thank you, Mr. Chairman, I 
appreciate it very much. I wanted to specifically thank Chair 
Rodgers for including two of my bills, the Gabriella Miller 
Kids bill with Representative Dingell and a couple others, but 
also the National Plan to End Parkinson's Act. Thank you very 
much for including them in today's hearing.
    The Gabriella Miller Kids First Research Act 2.0, H.R. 
3391, is legislation I colead, again, with Representative 
Wexton as well and, of course, Representative Tonko. And it 
would authorize the important pediatric research initiative at 
the National Institutes of Health, NIH. Sadly, cancer is the 
single leading cause of death of children in the United States 
of any disease, approaching 10,000 diagnosed annually, under 
the age of 15. We still have a long way to go to improve 
survival for our most vulnerable patients, our children, who 
are diagnosed with brain tumors, prevalent cancers, and other 
pediatric rare conditions. We must continue to allow this 
program to conduct the critical research needed to improve 
outcomes and accelerate treatments and cures.
    My other bill is H.R. 2365, the National Plan to End 
Parkinson's Act that I lead with Representative Tonko, and it 
would unite the Federal Government through an advisory council, 
public and private stakeholders, in a national effort and 
strategy to support research, development, recommendations with 
the goal of treating and curing Parkinson's disease.
    So I have a question for Mr. Manahan. And I tell you what, 
you did an outstanding job, sir. Thanks for sharing your story.
    Mr. Manahan. Thank you.
    Mr. Bilirakis. We really appreciate it very much. It makes 
a big difference when you hear the personal stories. Thank you 
again for sharing your story. Your advocacy is extremely 
impactful, and I greatly appreciate you sharing it.
    You have highlighted the burden that this disease has on 
the patient and the families physically, emotionally, and 
financially. I personally understand this. My uncle died from 
Parkinson's, late 50s, and my brother just passed way over--
just over a month ago, and Parkinson's. He was diagnosed in his 
mid-40s. My father has Parkinson's, early stages, and my 
mother-in-law, late--mid to late stages. So I understand the 
disease even though I am not a physician.
    So, again, this--the lack of treatment options leave 
patients, families, and the American taxpayers in a terrible 
predicament with little place to turn, as you said. Could you 
please elaborate on why this legislation is so vitally 
important right now? Time is of the essence.
    Mr. Manahan. Yes, sir. I am excited about the National Plan 
because for the first time it is going to give the Federal 
Government and stakeholders a chance to sit down and talk face 
to face. There is going to be a seat at the table where it 
hasn't been before for patients, caregivers, Parkinson's 
specialists and doctors. And I think without a mandate--without 
a mandate, it is not going to happen.
    And we need this plan because I fear that if we don't do 
something this year or next year, the problem is going to be 
that we will not come up with a cure for Parkinson's in years, 
which I hope, versus decades.
    Mr. Bilirakis. Thank you. And I want to also commend 
Michael J. Fox, obviously.
    Mr. Manahan. Yes.
    Mr. Bilirakis. What he has done, his foundation, what he 
has done to define treatments and potential cures for this 
disease, and I know they are behind this legislation as well. 
So he has been extraordinary, there is no question.
    I have talked extensively about the need to ensure we are 
coordinating Federal efforts. That is the key, coordination, 
rather than a duplicative and siloed approach to healthcare. 
And initiatives like Operation Warp Speed proved that with the 
right public-private partnership we can accomplish a 
significant amount.
    So again, Mr. Manahan, what will the creation of an 
advisory council mean for coordinated and comprehensive public 
and private research?
    Mr. Manahan. Well, I look at the biomarker which we--I had 
mentioned earlier today, as the hope for the future. But this 
legislation is the hope for people that have the disease right 
now. It is going to bring together the Michael J. Fox 
Foundation and the private foundations and the Federal 
Government. In fact, you know, I talked to someone who served 
on the advisory board for Alzheimer's, and one of the things 
she said to me was that this national plan really worked out 
well because the Federal agencies got a lot of opportunity to 
find out what they are doing.
    So it is just not the Federal agencies and the private 
foundations talking, it is actually the Federal agencies 
talking amongst themselves.
    Mr. Bilirakis. Yes. And this piece of legislation is 
modeled after that piece of legislation.
    Mr. Manahan. Yes, sir.
    Mr. Bilirakis. To cure Parkinson's.
    Mr. Manahan. Sure is.
    Mr. Bilirakis. I mean, Alzheimer's in this case. Thank you 
very much, and I really appreciate it. I have a couple more 
questions, but I am not going to go too far over.
    So I appreciate it, and I yield back, Mr. Chairman.
    Mr. Bucshon. The gentleman yields back. I now recognize Ms. 
Kuster--Mr. Ruiz showed up. I didn't see him down there. Dr. 
Ruiz----
    Mr. Ruiz. Thank you, Doc.
    Mr. Bucshon [continuing]. Is recommended--is recognized----
    Mr. Ruiz. I'm just clearing my throat. Allergies.
    Mr. Bucshon. I'm recommending him too.
    Mr. Ruiz. [Laughter.]
    Mr. Bucshon. But he is recognized for 5 minutes.
    Mr. Ruiz. Before I begin, I want to give a very special 
recognition and shout to students from my district from the 
Migrant Farmworker Education Program that are here visiting 
Washington, DC. They are--some of them are walking in right 
now. They are very, very, very special to me because my mother 
was a migrant farmworker who toiled the fields day in and day 
out with calloused hands and tired backs and minimal rest day 
after day after day. And they are attending the same schools 
that I attended, and I am true and blue from the farmworker 
community. And so if you don't mind, let's give them an 
applause for being here.
    [Applause.]
    Mr. Ruiz. Thank you. Thank you very much.
    I want to touch on two different topics here today. First, 
I would like to address the policy that would pull funding from 
children's teaching hospitals that provide age-appropriate 
gender-affirming care for transgender and nonbinary youth. I 
echo my colleagues who have already spoken out to protect the 
relationship between patients and their doctors, and this 
harmful and misleading rhetoric and policy that purports to 
protect kids is actually doing the opposite: It is a bully 
policy that bullies one of--some of our most vulnerable kids.
    Research shows that gender-affirming care improves the 
short- and long-term mental health and well-being of trans and 
nonbinary youth. The science is there, the studies are there, 
and every major medical association supports it. Decisions to 
get age-appropriate gender-affirming care is one that should be 
made by parents and their kids in consultation with their 
doctor, not by the Federal Government.
    And in addition to placing transgender and nonbinary 
youths' mental health at risk, these policies are also risking 
the future of our pediatric workforce. We already have a 
pediatric shortage. Children's hospitals train half of our 
country's pediatricians, and this proposed policy only forces 
those hospitals to choose between doing what is best for their 
patients or training the next generation of pediatricians.
    Dr. McNamara, as a doctor, and I am very concerned how this 
policy will harm the mental health of our transgender and 
nonbinary youth as well as the future pediatric workforce of 
our country. Can you address the consequences these policies 
will have both on our transgender and nonbinary youth and on 
our pediatric workforce?
    Dr. McNamara. It all goes hand in hand, sir. Thank you for 
your question because it highlights the fact that pediatric 
healthcare is a tightly knit fabric and you cannot pull out one 
thread; the whole tapestry would unravel. The healthcare of one 
child is--you know, we don't think about it like that, I guess. 
We don't parse out groups of youth and say, you know, well, it 
is OK to care for you and it is not OK to care for some of 
them.
    Mr. Ruiz. Correct.
    Dr. McNamara. So we simply would never accept this policy. 
As far as mental health goes, I mean, even just the rhetoric 
that we have heard today is very damaging and harmful to trans 
youth. I think that one of the reasons why rates of suicidal 
ideation over the past couple of years and other mental health 
harms in trans youth has been going up is because of how they 
have been demonized.
    Mr. Ruiz. Yes, and the rhetoric leads to depression, leads 
to anxiety, leads to suicidal ideation. It also encourages 
others to use the same rhetoric, their peers, that leads to 
bullying. Transgenders are already number one on the hate 
violence crime list.
    So I would like to pivot to another topic: cancer 
detection. Mr. O'Connor, thank you for your remarks today and 
for general president Ed Kelly's and the International 
Association of Fire Fighters' longstanding leadership in 
promoting the health and safety of our Nation's firefighters. 
Thanks to your work with Congress to establish the Firefighter 
Cancer Registry, we now know that cancer is the leading cause 
of death for firefighters, exceeding heart attacks, smoke 
inhalation, burn injuries, vehicular accidents, and other fatal 
injuries. In fact, firefighters face a cancer risk that is 14 
percent higher than other Americans', and it is truly an 
epidemic.
    So the IAFF's leadership goes beyond researching the data. 
You are leading the Nation in ideas. Look, I led the--help lead 
the effort on the burn pits and the associated ingestion of the 
toxic smoke, so I know that a lot of the things that burn have 
carcinogens.
    Will you--Mr. O'Connor, will you share with the committee 
how the ability to find more cancers earlier would benefit your 
retirees, their families, and so many others, at-risk seniors 
across the country?
    Mr. O'Connor. Real quickly before I answer that directly, 
I----
    Mr. Ruiz. You only have 15 seconds.
    Mr. O'Connor. I know, I know. I want to add that wildfires, 
the constant smoke is exposing to everybody, including 
citizens.
    Mr. Ruiz. I agree.
    Mr. O'Connor. Screening is the key. Screening is the key. 
If we get our people in early and we are able to track it, we 
will be able to solve the--we will be able to cure the cancers 
and catch them at early stages. But screening is crucial.
    Mr. Ruiz. Great. Well, I truly support this bill, and I 
also have another bill called the Nancy Gardner Sewell Medicare 
Multi-Cancer Early Detection Screening Coverage Act, which will 
be able to more efficiently detect cancers early, and I 
encourage the committee to also look into that one.
    Mr. O'Connor. I know we expired. I mentioned that in my 
oral testimony.
    Mr. Ruiz. Thank you. Bye.
    Mr. Bucshon. The gentleman yields back. I now recognize Mr. 
Johnson from Ohio, 5 minutes.
    Mr. Johnson. Well, thank you, Mr. Chairman. I want to thank 
Chairman Guthrie for having this hearing today, and thank you 
to our panelists for joining us here today.
    We are considering a number of bills and important 
reauthorizations here today, including the Children's 
Hospitals' Graduate Medical Education Payment Program, which 
funds freestanding children's hospitals. This money helps their 
graduate medical education programs train resident physicians 
and dentists.
    We all understand the toll that the pandemic took on the 
most vulnerable in our society, particularly our children, from 
not being able to go to school--something we will not know the 
true side effects of for years to come--to masks, and anxiety. 
COVID-19 weighed heavy on America's boys and girls.
    It is critical that we support our Nation's children's 
hospitals. Nothing is more important to me than ensuring the 
mental and physical health of our young people. That is why I 
am proud to support Representative Crenshaw's legislation 
reauthorizing the graduate medical education payment program.
    Yes, I am deeply troubled by reports that a growing 
consortium of American medical professionals are pushing highly 
controversial treatments like gender-affirming surgeries, 
hormone therapy, and puberty blockers on children and teenagers 
when we do not know the true impact of their long-term mental 
and physical health.
    So question number one: Dr. Grossman, in your position as a 
child, adolescent, and adult psychiatrist, what types of 
treatment methods for kids diagnosed with gender dysphoria are 
backed by scientific data? If you need me to repeat that, I 
will.
    Dr. Grossman. No, no, no, I heard you. Thank you very much, 
Congressman, for the question. We have known for decades that 
if these kids are left alone or just given psychotherapy and 
family support, that the vast majority will become comfortable 
with their sex, with being a boy or a girl. We have known that 
for a very long time.
    Recently, we have started applying so-called gender-
affirming care to a new cohort, a new group of kids that we 
have never seen before, and those are kids who suddenly out of 
the blue develop the gender dysphoria as part of what more and 
more people are realizing is a social contagion.
    Mr. Johnson. So you are saying that if they received the 
kind of support at home and mental health counseling, 
traditional mental health counseling, that they grow through 
this phase and they become comfortable with who they are?
    Dr. Grossman. I am not--yes. I am not saying every single 
person.
    Mr. Johnson. Sure, sure.
    Dr. Grossman. But in the past, the research that has been 
done on those kids would say so.
    Mr. Johnson. Well, that is interesting because, you know, 
as my colleagues across the aisle frequently like to say, we 
need to follow the science here. In Dr. Grossman's opening 
remark, she noted that the United States is moving in the 
opposite direction from our European counterparts in terms of 
how those nations view gender dysphoria treatment. Simply look 
at our friends in Great Britain. Just recently the National 
Health Services in London announced that publicly funded 
services will no longer routinely offer puberty blocking drugs 
to children.
    This on the back of a 2023 global public opinion survey of 
30 countries asking whether or not transgender teens should be 
allowed to receive gender-affirming care. This survey showed 
the United States as having even less public support for these 
treatments than virtually every single European country polled, 
including the UK.
    The fact of the matter is the United States is moving in 
the wrong direction. It is moving in a very extreme direction 
and is becoming a global outlier on this issue. I personally 
believe it is irresponsible and essentially child abuse to 
allow minors to make these types of life-changing medical 
decisions. But on the facts, we simply do not know enough to 
say for certain that we should be allowing these treatments at 
all.
    I find it disturbing that some children's hospitals are 
pushing puberty blockers or hormone therapies on children 
incapable of understanding the lifelong--long-term effects of 
these treatmentss. Children's hospitals are meant to be the 
gold standard of pediatric care in our communities, and their 
support for such programs will lead parents and families to 
trust what they are saying despite the data telling a different 
story.
    I do have other questions that I will submit for the 
record, Mr. Chairman. I realize my time is expired. This is a 
real important and emotional issue for many of us, especially 
those of us who are grounded in our faith and as parents. We 
see this as an aberration and----
    Mr. Bucshon. The gentleman's time is expired.
    Mr. Johnson. I yield back.
    Mr. Bucshon. I now recognize Ms. Kuster for her 5 minutes.
    Ms. Kuster. Thank you, Chairman Guthrie. I am glad this 
committee is dedicating time to reauthorizing several important 
health programs, all on a bipartisan basis. The list is 
impressive: supporting premature infants, expanding the dental 
workforce, committing Federal resources to end Parkinson's, 
protecting our firefighters, to name a few.
    Today's hearing should be an opportunity to celebrate the 
important role that Congress plays in dedicating resources to 
people with rare diseases and providing support to our 
country's health workforce. However, I am extremely 
disappointed as a parent that today's hearing includes a 
partisan attempt to villainize children and bring politics into 
our healthcare system.
    I recently had a lovely breakfast with our Chair. We share 
a concern about the well-being of our youth. But I want to 
quote her comments at the beginning of this hearing. She said 
she wants to send a message to our children ``that they are 
loved as they are.'' Trying to scare our Nation's pediatric 
hospitals into denying gender-affirming care to patients to fit 
a political agenda is not just cruel, it is nonsensical, and it 
puts the health of millions of children at risk.
    As Dr. Ruiz has recounted and our experts today have 
affirmed, this type of rhetoric from Members of Congress in 
hearings like this leads to suicidal ideation and bullying and 
is harmful to our children. Let's make one thing clear right 
now: The Government has no role in policing what care doctors 
and nurses should provide to their patients. Medical decisions 
are between a patient, their family, their parents, their 
guardian, and their physicians. Trying to insert the Federal 
Government into these incredibly private, incredibly sensitive 
decisions is simply unacceptable.
    In my home State of New Hampshire, our State motto is to 
``Live Free or Die.'' We value privacy, we value the privacy of 
our medical decisions, and we do not need the United States 
Congress to interfere in that privacy. This legislation flies 
in the face of our State motto.
    So, Dr. McNamara, in your testimony you state that 
healthcare providers must consult with parents and legal 
guardians about care that is provided to children. Could you 
explain to this committee and to my colleagues the importance 
of informed consent when providing all kinds of medical care to 
our youth?
    Dr. McNamara. Absolutely. Thank you for your question, 
Congresswoman, and the thank you for your comments. It makes my 
patients feel safer.
    So parents play a central role in all medical decision 
making for minors in the vast majority of cases, and regarding 
medical treatments for gender dysphoria, it is no exception. 
Parents know their kids best. They know what they need. We as 
pediatricians rely on their knowledge of their young person in 
order to help support them best.
    In the case of medical treatments for gender dysphoria, the 
standard of care and the way that care is practiced in this 
country is with a multidisciplinary team with an--excuse me, an 
iterative over several visits, several months, mental health 
assessment, and long conversations that don't really have an 
end point. That may be a little bit different from other 
aspects of pediatric care, but it is something that my 
colleagues are--and I are very skilled at doing. We know how to 
do it. And this care overwhelmingly benefits transgender youth.
    Ms. Kuster. I just have to--as an aside, I was an adoption 
attorney for 25 years, and I primarily represented birth 
parents who made the decision to place their children for 
adoption. And I can remember working with two teenagers. I 
remember when we went before the judge, looking over and 
realizing that the young man had never shaved, he still had the 
peach fuzz on the side of his face. And trust me, there was no 
room for the Federal Government in making those personal, 
private decisions about our health, our well-being, and the 
well-being of our families.
    I just want to say that the claims that we hear about 
gender-affirming care in this room and in the media are 
dangers, and I want to join my Chair in sending a message to 
our children that they are loved as they are. Thank you so 
much.
    I yield back.
    Mr. Bucshon. The gentlelady yields back. I now recognize 
myself for 5 minutes for my line of questioning.
    I am a physician, and I understand the issues related to 
gender dysphoria, and I do recognize it is real. However, I can 
never support permanent surgical procedures on children, 
regardless of other--the other need for treatment for their 
dysphoria. Again, I would remind everyone, these are 
irreversible. Permanent surgical procedures, in my view, should 
not be part of a treatment plan for transgender children.
    In the House Energy and Commerce Committee, look, we are a 
legislative workforce. You look at the House floor, a lot of 
our bills come from here. And we manage to do much of our work 
on a bipartisan basis, and we are doing I think mostly that 
today. And I am proud of that. We are continuing to be a 
workhorse for Congress as we have a number of important public 
health priorities we are discussing here today.
    So I am going to ask a couple of questions. Doctor--is it 
Dr. ``Sher-oh''? Dr. Cherot, in Indiana we have the third-
highest maternal mortality rate in the Nation, with 44 deaths 
per 100,000 live births as of 2022. According to the March of 
Dimes' own data, Indiana has an infant mortality rate of 6.6, 
which is higher than the U.S. rate of 5.4. These are statistics 
we are not proud of, but our Governor and our State government 
as well as the medical community, are trying to find ways to 
improve this, and we are focusing on that.
    Can you talk about how H.R. 3226 and H.R. 3838 will benefit 
mothers and babies in States like Indiana and how we can--how 
this will help us advance?
    Dr. Cherot. Absolutely. Thank you for the question. The--
within States we have our MMRCs and our really important--to 
look at the details of the deaths that do happen. And what 
happened is that we identify those contributing factors, using 
that to then translate those into action. And those MMRCs are 
important across every State to collect that data.
    I would say that the Federal collection activities underpin 
the work of the March of Dimes and that those agencies and 
partners address the maternal and infant health crisis. We want 
to increase that data to get to solutions that are vital to be 
able to impact.
    Mr. Bucshon. Well, thank you. I just want to say we have 
had a hearing in the past--a number of hearings in the past on 
this, and we had data out of Parkland Hospital in Dallas, 
Texas, a famous hospital, and their data is outstanding on this 
issue----
    Dr. Cherot. Yes.
    Mr. Bucshon [continuing]. On maternal mortality. And they 
have defined protocols on how they manage----
    Dr. Cherot. Yes.
    Mr. Bucshon [continuing]. The patients. And their patient 
population are primarily the underserved, uninsured, and also 
ethnically diverse population, so it can--this can be done, 
correct?
    Dr. Cherot. Yes, absolutely. We have seen States that have 
changed their outcomes using different PRQCs to get to really 
standardized protocols, realizing that there are lots of 
impacts that we can have both on maternal death rates as well 
as preterm birth.
    Mr. Bucshon. Yes, and it is shocking that this does cross 
socioeconomic class also. We--you may or may not know, we just 
had a famous athlete who was----
    Dr. Cherot. I do.
    Mr. Bucshon [continuing]. Who we found out what resulted in 
her death, tragically, at home, and why that happened I don't 
think we know.
    Dr. Thompson, can you talk about what innovation means to 
patients with sickle cell disease? That is kind of open ended. 
I want you to basically comment on what you want to say about 
where we are in innovation and what we can do.
    Dr. Thompson. Thank you. And innovation actually is a 
spectrum. Innovation in--I think in its best possible terms 
really is looking at discovery science that moves to the 
bedside. And so, if I were to look at the best-case scenario 
today, today is a possibility of gene therapy for a variety of 
blood disorders and immunodeficiencies.
    For some people, innovations is what I otherwise call 
standard of care, because today there still are individuals in 
this country whose current providers, whose current communities 
lack resources for them to actually understand what is 
available to them. So we know that there are now a number of 
disease-modifying therapies that have been FDA approved across 
a wide range of ages. If innovation means that those 
individuals now have access to those, then certainly that 
should also be a form of innovation that I hope we would also 
embrace.
    Mr. Bucshon. Yes. I will finish with this. I did my medical 
school at the University of Illinois in Chicago, and at Cook 
County Hospital we had a lot of people come in with--in sickle 
crisis, and this is just a--you know, if we--particularly 
genetic therapy is exciting because it is just a tragic 
disease. Also people in renal failure and organ--other organ 
failure because of it. So I am excited about the future, 
particularly of gene therapy in diseases like sickle cell.
    With that, I yield back.
    And I recognize now Ms. Craig for her 5 minutes.
    Ms. Craig. Thank you so much, Mr. Chairman. I am incredibly 
disappointed to see my Republican colleagues today taking what 
has always been a bipartisan effort to reauthorize a program 
that we have always supported and twisting it into a partisan 
process that undermines parents' rights and ignores evidence-
based care guidelines for the treatment of trans youth.
    We should be here today to support a clean reauthorization 
of the Children's Hospital Graduate Medical Education Program. 
But oh no, you are putting the program in jeopardy in support 
of your continued culture war crusade. Look, I have a newsflash 
for my colleagues: It is none of your business what evidence-
based care a parent in consultation with their healthcare 
provider decides for their child. In fact, after listening to 
you today, I am absolutely certain that most of you have no 
idea what the range of gender-affirming care actually is. So 
let me start with that.
    Dr. McNamara, can you define for us what age-appropriate 
gender-affirming care actually is for my colleagues? Just a 
little bit.
    Dr. McNamara. This is absolutely crucial. Thank you so much 
for the question. Gender dysphoria is real. It represents a 
discordance and distress that emerges from the difference 
between--I minced my words. It is the difference--I minced my 
words again. I am so sorry.
    It is distress that emerges from the difference between sex 
assigned at birth and gender identity. Without treatment, this 
care--with this condition is dangerous and debilitating. 
Gender-affirming care starts with affirmation. It starts with 
very simple things like is it OK to get a haircut, is it OK to 
wear certain clothes, or to change your name into something 
that feels more authentic.
    And from there, we see that youth begin to blossom. Some 
youth qualify for and desire medical aspects of gender-
affirming care, and it is a highly individualized process. It 
depends on who the young person is, their parents, and the 
conversations that evolve from there. There is no end point and 
there is no prescripted plan of care. It depends on the person 
who is before us.
    Ms. Craig. And, Dr. McNamara, that care has been supported 
by 20 major medical associations, including the American 
Academy of Pediatrics, the American Psychological Association, 
and the American Medical Association. Am I correct?
    Dr. McNamara. Absolutely.
    Ms. Craig. Can you just for a moment rebut the claim that 
has been made here today that the United States is somehow an 
outlier in the care that gender-affirming care represents?
    Dr. McNamara. So I urge this body to make any decisions 
based on sound information and science. No other country in the 
world who is a peer of the United States has gone as far as to 
ban and criminalize the provision of medical treatments for 
gender dysphoria. What you have heard today is a cherry-picked 
collection of unverified information that portrays outlier 
views in some countries in this world.
    There are many countries in this world that nobody has 
brought up today that I could list off, like Ireland, 
Australia, Spain, Portugal, Canada, Mexico, among others. But 
this is the greatest country in the world, right, and our 
medical science and innovation here is amazing. I am so 
privileged to be able to practice this care.
    Ms. Craig. Dr. McNamara, thank you so much. You have 
already spoken to how dangerous it can be if that care is 
denied or if medical professionals are not appropriately 
trained in order treat this and provide this care.
    I get that some of my colleagues think this topic is a 
political winner. I would extend an invitation to every single 
one of you, many of whom I respect, to attend a panel of 
parents of trans youth to hear their stories. What you are 
attempting today undermines the rights and responsibilities of 
the parents of trans kids and is opposed by all the major 
medical organizations in our Nation.
    We agree, Madam Chair--I have so much respect for you--that 
the goal is to love our children for who they are. Some of our 
children are transgender. Do we have enough space in our hearts 
to love and accept them, too, for who they are? Some of your 
kids and grandkids will be trans. Do you really want any 
politician sitting in this room involved in their healthcare 
decisions?
    And with that, I yield back.
    Mr. Bucshon. The gentlelady yields back. I will now 
recognize Mrs. Harshbarger for 5 minutes. I surprised her.
    Mrs. Harshbarger. Yes, you surprised me. Thank you, Mr. 
Chair. I thank all the witnesses for being here.
    And, Mr. Manahan, I am proud to be an original cosponsor of 
the National Plan to End Parkinson's Act introduced by Reps 
Bilirakis and Tonko. The bill aims to unite the Federal 
Government in a mission to cure and prevent Parkinson's and 
alleviate financial and health burdens on American families and 
reduce Government spending over time. And the biomarker which 
detects the protein that is associated with damaged neurons 
that is used--now you can detect Parkinson's earlier is amazing 
to me.
    My father has suffered from Parkinson's. He will be 90 next 
month. And it is an ongoing battle, and I understand everything 
you are talking--the younger you are, the more problems you 
have as you age.
    The National Institutes of Health is a Federal agency with 
the largest budget for supporting Parkinson's disease research, 
I think 259 million in 2022.
    Mr. Manahan. Mm-hmm.
    Mrs. Harshbarger. My question is, do you have a sense of 
what the NIH thinks of this legislation?
    Mr. Manahan. Well, Dr. Richard Hodes, who is the Director 
of NIA, testified in the Senate and answered a question from my 
senator, Senator Shelly Moore Capito, about whether or not they 
thought that the national plan would be a--something that they 
would support. And his quote is he found it to be 
extraordinarily valuable. I have not had any other 
conversations with NIH or NIA, but apparently the NIA, Richard 
Hodes, has--supports it.
    Mrs. Harshbarger. OK.
    Mr. Manahan. Thank you.
    Mrs. Harshbarger. Thank you.
    Dr. Cherot, I know the March of Dimes is a strong advocate 
for the PREEMIE Reauthorization Act and to reauthorize the 
important Federal research education intervention programs to 
improve pregnancy outcomes and infant health, of course, to 
reduce the premature, preterm births and infant mortality, and 
I am pleased we are taking that legislation up.
    I wanted to ask you about another issue, though, that has 
come across my desk. It is about the aluminum content in 
parental nutritional products. It has been recognized for 
decades as a toxic contaminant, especially dangerous for 
preterm babies due to their immature kidney function where they 
can't, you know, expel that, and it causes bone toxicity, brain 
toxicity, developmental delays, and premature babies are 
especially susceptible to aluminum toxicity because of their 
digestive systems that are not fully functioning.
    Previously, the FDA took the position that preterm infants 
not receive more than 4 to 5 micrograms per kilogram of body 
weight of that aluminum product. Now the FDA is poised to raise 
that aluminum to almost 17 times the previous approved 
standards.
    Does the March of Dimes agree that we should continuously 
strive to reduce those aluminum levels in prenatal products and 
that the FDA should not approve or permit to remain on the 
products with high aluminum levels when lower aluminum products 
are available?
    Dr. Cherot. So, first, I appreciate the question, but I am 
not a nutritionist, nor am I a neonatologist. So I am an 
obstetrician/gynecologist.
    Mrs. Harshbarger. OK.
    Dr. Cherot. But I would say the March of Dimes is 
absolutely advocating for research in nutrition.
    Mrs. Harshbarger. Mm-hmm.
    Dr. Cherot. Breastfeeding as well as nutritional 
supplements to look for the best things for premature birth for 
those babies. But I would have to get back to you on that 
answer.
    Mrs. Harshbarger. Yes. Yes, I wish you would do some 
research on that because there is----
    Dr. Cherot. I'll note that. Yes, absolutely.
    Mrs. Harshbarger. Yes, there's a lot of toxic side effects 
associated with that aluminum product. So for them to change 
course on this is to me unacceptable. So thank you for that.
    And with that, Mr. Chairman, I yield back.
    Mr. Bucshon. The gentlelady yields back. I now recognize 
Ms. Kelly for her line of questioning.
    Ms. Kelly. Thank you so much, Mr. Chair. I am so happy to 
see so many bipartisan bills to improve the state of health--of 
the healthcare system for all Americans. First I would like to 
recognize the bipartisan Action for Dental Health Act of 2023 
that I gladly led with my colleague Rep Mike Simpson. Oral 
health affects our ability to eat, speak, smile, and show 
emotions. Oral health also affects a person's self-esteem, 
school performance, and attendance at work or school.
    Regular, preventive dental care is essential for oral good 
health so one can find problems earlier when they are easier to 
treat. Unfortunately, many don't get the care they need. More 
people are unable to afford dental care than other types of 
healthcare. Children, low-income Americans, minorities, and the 
elderly are especially at risk for having limited dental care 
and poor health outcomes.
    I would also like to submit for the record a letter from 
the American Dental Association in support of this legislation, 
which provides a crucial workforce grant program focused on 
providing access to care for those most in need.
    Additionally, I am elated to see so many bipartisan bills 
being brought forward to address the maternal health crisis. I 
would like to take this moment to pay respects to Tori Bowie, a 
32-year-old Black woman who was an Olympic-winning track star. 
Unfortunately, she passed away on May 2nd. A preliminary 
autopsy has determined that her cause of death is attributed to 
possible complications of pregnancy.
    And I am so tired of learning about these stories, 
especially when data shows that 84 percent of maternal deaths 
are preventable. This is unacceptable. I will continue to work 
on legislation to address this issue.
    I would like to thank my colleague, Rep Burgess, for 
including a piece of my MOMMAs bill in the Preventing Maternal 
Death Act, and I would lock arms with anyone who wants to make 
this country the safest place to give birth.
    Dr. Cherot, would you please elaborate on how maternal 
mortality review committees determine if a pregnancy-related 
death is preventable, and do any State MMRCs in particular 
stand out as a success story so we can continue to promote best 
practices?
    Dr. Cherot. So first, thank you. Yes, MMRCs are crucial at 
getting at the data, and they need--their State, Federal--
really getting to all of the data from the stakeholders and 
getting to our PQRCs. Our maternal mortality rates are better 
in some States than others. Our--and just as the March of Dimes 
puts out data on maternity care deserts and preterm birth, we 
also look at this data exclusively.
    Specifically for your State, I am dragging data through and 
hoping that my crowd is pulling up yours. But there are some 
that are much, much better because they take the data and then 
really put into action some of the stuff that comes out of the 
American College of OB/GYN and AIMs, really looking at how do 
we standardize protocols and procedures were some of the most 
crucial, like hemorrhage, like cardiovascular. And we have made 
huge efforts in those, and there is more to come that needs to 
be done. And clearly Black and brown women are suffering in 
this country, and our Olympian died in the month of May.
    Ms. Kelly. Mm-hmm.
    Dr. Cherot. And she died--what they think, we don't know, 
but what has been put out in the press is on eclampsia, which 
is seizing. I have dealt with this many a time, and it is 
preventable.
    Ms. Kelly. Right.
    Dr. Cherot. And she was supposedly found in labor and 
preterm labor.
    Ms. Kelly. Mm-hmm.
    Dr. Cherot. So not only do these women suffer, their babies 
are dying, too, and are more likely to. So thank you for 
bringing that to the attention.
    Ms. Kelly. Well, thank you for your work.
    And I just wanted to tell Mr. Manahan, my grandmother had 
Parkinson's. And I wanted to thank Mr. O'Connor for your 
service. I used to work for local government, so I know how 
important you are.
    Lastly, I would just like to state that it is unacceptable 
that clinics and clinicians that provide gender-affirming care 
to our youth have seen a rise in harassment and death threats. 
I have heard from those who are on the front line and want to 
speak up but are remaining publicly silent for the safety of 
themselves and those around them. This is unacceptable in our 
society. I am proud to speak up and speak out on their behalf.
    Defunding postgraduate pediatric training programs if they 
give proper care to transgender youth is reckless and 
dangerous. The Federal Government should not be involved in the 
healthcare decisions between a parent and their child.
    And with that, I yield back. Thank you.
    Mr. Bucshon. The gentlelady yields back. I now recognize 
Mr. Carter for 5 minutes.
    Mr. Carter. Thank you, Mr. Chairman, and thank all of you 
for being here. This is extremely important. And as a 
healthcare professional, healthcare outcomes have been my focus 
since I have been a Member of Congress and long before that, 
even when I was a member of the Georgia State Legislature.
    I am from Georgia, and we have one of the highest maternal 
mortality rates in the country. And for the life of me, I 
cannot figure that out. It baffles me. I do not understand why 
Georgia has such a high maternal mortality rate. And it is 
something that I have worked on for probably the last--when I 
was in the Georgia State Legislature and when I have been here, 
so probably 20 years, and I think I am just as confused now as 
I was when I started, and it is really disappointing.
    The CDC just recently released data that showed that the 
number of pregnancy-related deaths in the United States 
continued on an upward trend in 2021, with over 1,200 deaths 
that year. Twelve hundred. In America, in the United States. 
And, again, I am just baffled by this. But I am proud that I am 
coleading along with Dr. Burgess legislation to Preventing 
Maternal Deaths Reauthorization Act, and hopefully we can get 
that passed, and I think we will, and it is very important.
    Now I know you were just talking about maternal mortality 
review committees, and they are very important. In fact, when I 
was in the Georgia State Legislature, we passed Senate Bill 
273, which created the MMRCs, putting it into the Georgia 
Department of Public Health, and it was one of the things that 
we have done to address this embarrassing situation that we 
have in our State.
    Dr. Cherot, I wanted to ask you--again, we have talked 
about the role of MMRCs and--but why are they so important?
    Dr. Cherot. Well, they are vital in understanding the 
causes and implementing changes to prevent future tragedies. 
Most of the information on maternal deaths cited today are 
based on data from MMRCs, and we need more of it.
    Mr. Carter. OK. Well, let me ask you, are you familiar with 
Georgia and how----
    Dr. Cherot. Yep.
    Mr. Carter [continuing]. They are using it?
    Dr. Cherot. So----
    Mr. Carter. Because that was legislation I worked on when I 
was in the legislature there.
    Dr. Cherot. Yes. Because the Preventing Maternal Deaths Act 
grant funding to be sustained so, yes. In Georgia, they 
recently published a series of recommendations for providing 
these case management services for women during pregnancy and 
up to 1 year postpartum, implementing a blood pressure check at 
72 hours--not 3 weeks, not 2 weeks, but 72 hours after 
discharge when a patient has pre-eclampsia.
    Mr. Carter. Good.
    Dr. Cherot. They educate patients, right? They also provide 
reproductive life planning and counseling, and they improve 
communication coordination for patient care----
    Mr. Carter. Good, good. Well, thank you.
    And I want to shift gears real quick and talk about sickle 
cell disease because, again, here we are in Georgia and we have 
got some of the highest rates in--and, you know, I am proud of 
my State, and I love my State, it is my home, it is where I 
have lived all of my life, where I intend to live the rest of 
my life, but I just cannot figure out why we are leading in 
some of these things. And sickle cell is--and as a pharmacist, 
I know and I have seen and witnessed just how awful a disease 
it is and how painful it is. But we are home--Georgia is home 
to one of the largest sickle cell disease populations in the 
country.
    Dr. Thompson, how does--and let me preface this by saying 
that Dr. Burgess, again, and I have legislation that we are 
cosponsoring, H.R. 3884, the Sickle Cell Disease and Other 
Heritable Blood Disorders Reauthorization Act. So how does the 
reauthorization of critical cell disease programs ensure that 
patients have the support and resources that they need?
    Dr. Thompson. Well, the principal benefit of this Act 
really is to the extent that we actually can disseminate the 
education and training, moving it from our academic medical 
centers to where the patients are. And so really having--
utilizing the hub-and-spoke model for actually getting more 
information, more knowledgeable providers and taking care of 
sickle cell disease.
    I should also note, especially from your State of Georgia, 
that the benefits of actually combining the work that HRSA does 
with the data collection from the CDC has also been quite 
helpful. That the Centers for Disease Control started out with 
two States, Georgia and California, and that that data from 
those two States has helped to inform----
    Mr. Carter. Good.
    Dr. Thompson [continuing]. Better ways to actually identify 
patients and to treat them.
    Mr. Carter. Great, great. I am sorry, I don't have long, 
but do you want it? I will yield to the lady from Washington.
    Mrs. Rodgers. Thank you. I appreciate the gentleman 
yielding.
    I just wanted to address the CDC bills. We are considering 
these specific individual reauthorizations today because they 
are set to expire, but we also plan on looking at broader CDC 
authorization and reform this Congress. We must do our job as 
authorizers to ensure these programs are operating as intended, 
with proper accountability and oversight.
    CDC has a history of often relying on Section 301 or 317 of 
the Public Health Service Act, which provides very broad 
research and grant authorities to continue these programs, even 
if Congress does not specifically reauthorize them. These 
authorities were initially crafted in the 1940s and 1960s and 
then built upon further since then. As a part of looking at CDC 
reform, I think perhaps a good initial step would be to examine 
the use of these broad authorities and ensure that there is 
transparency as to when, how, and to what extent they are given 
as well as if these authorities are even still necessary at 
all, given work on smaller programs like the ones that we are 
considering today.
    I appreciate the gentleman yielding.
    Mr. Carter. And I will yield back. Thank you, Mr. Chairman.
    Mr. Bucshon. The gentleman yields back. I now recognize Dr. 
Schrier for 5 minutes.
    Ms. Schrier. Thank you, Dr. Bucshon, and thank you to all 
of our witnesses here today.
    I want to just talk about two things today. First is 
Children's Hospital Graduate Medical Education funding, and the 
other is direct primary care. I am going to start, just like so 
many of my colleagues, just up in arms that this funding would 
be held hostage for political gains.
    I am a pediatrician. My residency training was funded by 
CHGME. That was at Children's--Lucile Packard Children's 
Hospital at Stanford. And I understand how important that 
training is and that pediatricians need to be trained in a 
whole gamut of care and need to be prepared for whomever comes 
in their office.
    Children's Hospital GME funding has been reauthorized on a 
regular basis five times in a bipartisan way since 1999, has 
increased the number of pediatricians available to all of us 
and our kids. Right now, thanks to COVID and a number of other 
factors, we are facing a shortage of pediatricians and other 
physicians. This is coming at a time of increased need. We hear 
a lot of discussion in this committee and elsewhere about 
children's mental health and increased needs.
    And it is just unimaginable to me. I mean, frankly, until 
today's hearing, I could never have thought that this funding 
would be held up for some sort of political agenda, and putting 
kids who are already bullied and vulnerable right at the center 
of it.
    This program needs to be reauthorized in a timely fashion. 
Children's hospitals depend on it. I just--the Children's 
Hospital Association has requested a clean authorization. I 
would like to submit a letter into the record on this 
specifically from the Children's Hospital Administration.
    Mr. Guthrie. No objection.
    [The information appears at the conclusion of the hearing.]
    Ms. Schrier. Because healthcare--whether we are talking 
about women's healthcare or children's healthcare or other 
training of physicians--this is not something that should be 
dictated by politicians. I don't have any questions about that 
particular topic.
    The other topic is about direct primary care, and I am 
excited to see that the Medicaid Primary Care Improvement Act 
is on the docket today, clarifying that Medicaid can utilize 
the direct primary care model. This is designed around 
healthcare, not fee-for-service billing, and the way it works 
is patients or Medicaid or insurance companies pay an 
affordable monthly fee that allows doctors the time they need 
to just really work on their patients' health.
    Doctors have a certain number of patients in their panel 
who they are responsible for providing the best possible care 
for. A smaller patient population often means that more time 
can be spent on preventative care, diet, counseling, 
preventative measures. And it often turns into a better 
relationship between doctor and patient, fewer visits to the 
emergency room, and better outcomes.
    One doctor in my State, Dr. Garrison Bliss, is a pioneer in 
this effort. He has done it in many different contexts, 
including Medicaid. Was one of the first in Washington State. 
And he notes that most of his patients are over 60 years old, 
and none of them died from COVID. And he credits that 
relationship and close contact and avoidance of ER visits. This 
model of care just deserves to have more pilots around the 
country, hopefully with similar results.
    And I was just going to ask Dr. McNamara, first, thank you 
for speaking so beautifully about the care of transgender kids, 
and if you want to add anything or correct the record on that, 
you are welcome to do that in the remaining minute, but I also 
wanted to ask you whether this direct primary care model, how 
that would affect your practice and the relationship you have 
with your patients.
    Dr. McNamara. Thank you, Congresswoman, and it is a 
pleasure to speak to a fellow pediatrician.
    Primary care is the foundation of health and wellness in 
this country. It is a privilege to take part in our primary 
care system and to see children flourish into adolescents who 
become my favorite patients.
    As far as correcting the record, it is difficult to do so 
in a way that does justice to the amount of misinformation that 
we have all heard today. I urge this body to deliberate over 
the extensive documents that have been submitted to the record 
that debunk this disinformation and misinformation and to base 
their decisions on science.
    Ms. Schrier. And I will just add in my 10 seconds that I 
appreciate your noting how much engagement with the patient and 
the family happens with counselors, psychologists, 
psychiatrists, physicians, endocrinologists to make sure that 
you have got this right and the care that these children and 
young adults really deserve. I wanted to call attention to that 
thoroughness and the care that you provide. Thank you.
    I yield back.
    Mr. Guthrie. Thank you, the Congresswoman yields back. The 
Chair now recognizes Mr. Crenshaw from Texas for 5 minutes.
    Mr. Crenshaw. Thank you, Mr. Chairman. I first want to 
thank my friend, Representative Schrier, for her great 
bipartisan work on the direct primary care bill that we have 
been working on. It is--look, there's a lot of things we can 
agree on, and this is certainly one of them, and this is a 
small step in the right direction. I am really excited that we 
are going to get this through.
    But now there are some things we disagree on here, and that 
is what we have been talking about a lot in this hearing. So 
let's shift focus to the giant elephant in the room, and this 
is the reauthorization for the Children's Hospitals GME 
funding. And, yes, it is true, this is my bill, and what it 
does is it withholds funding from these hospitals if they 
engage in what they call gender affirmation therapy, these 
physical changes to a child's physiology, permanently 
disfiguring them through either puberty blockers or even 
surgical modifications.
    Now, look, I understand that the other side of the argument 
here believes they are on the side of compassion, and maybe 
that is a sincerely held belief. It is just as true that I 
believe we are on the side of compassion. I think it is indeed 
compassionate to stop kids from being permanently, physically 
altered based on little to no evidence that it will improve 
their underlying mental condition.
    Now why is this controversial? That is actually beyond me. 
Not too long ago I think we all agreed that performing double 
mastectomies on a 12-year-old girl was wrong. Now it has become 
a political movement where radical activists have bullied 
mainstream medical associations and Members of Congress into 
repeating this propaganda.
    Now it should be noted that in the public this subject is 
actually not very controversial. In fact, a recent poll just 
last month by the Washington Post showed that 68 percent of 
Americans opposed using puberty blockers on children. That is 
just a question about puberty blockers. Imagine if the question 
had been about castration or surgical interventions.
    So you have got to convince me that 70 percent of Americans 
are just a bunch of fools that refuse to accept the so-called 
science. Or maybe--look, I have another theory. Maybe they have 
a very baseline understanding of ethics and common sense which 
tells us that maybe--just maybe--it is a bad idea to submit 
children to permanent life-altering medical interventions based 
solely on a temporary ideation about their gender.
    Gender affirmation is not science, and there is no 
evidence-based standard of care. To say that is a lie, or is at 
best redefining the term ``evidence-based.'' What this is, is a 
social contagion. It is based in pseudoscience and radical 
ideologies, and it is sweeping across our country and 
encouraging children to make irreversible changes to their 
gender. What is worse, it is coming from adults and 
institutions who know better, to include our children's 
hospitals and institutions that are supposed to be tethered to 
sound science and their Hippocratic Oath of ``Do no harm.''
    Now, maybe I am an optimist, but I do believe that science 
and evidence will win out in the end, and in the future we will 
look back at these gender-affirming therapies as we now look at 
lobotomies and electric shock therapies. I have some reason to 
be hopeful. Notably, Great Britain's National Health Service 
restricted these clinical interventions from minors just last 
week. Reviews published in the British Journal of Medicine, the 
Journal of the Endocrine Society, even in the American Academy 
of Pediatrics, all cite the lack of evidence.
    We want to submit for the record this review published in 
the Journal of Endocrine Society that found that there is ``low 
quality evidence for the idea that hormonal treatment improves 
quality of life, depression, and anxiety among adolescents.'' 
Now here is the important part: This was a systematic review, 
which by definition is not cherry-picked data, but it is an 
all-encompassing review of all the data. It has thoroughly 
debunked the notion that any of these treatments are evidence-
based, let alone recognized as standard care. My colleagues are 
using these terms not as accurate representations of the data 
but as propaganda.
    Now, this funding program is reauthorized every 5 years. It 
provides taxpayer funds to train resident physicians at 
children's hospitals across the country. It is true, it has 
been a bipartisan funding mechanism for years. Let's keep in 
mind something, though: This is taxpayer money, and when 70 
percent of taxpayers oppose these barbaric treatments on 
minors, then taxpayer money should not fund it.
    That is why I am stipulating that as part of this 
reauthorization we will not provide any funding through this 
program to children's hospitals that push gender transition on 
minors through puberty blockers, hormone therapies, and 
surgeries. Now let's be clear, because there is another lie 
that's been told: It does not prevent any mental health 
therapies at all. Despite these lies being told, it does not 
prevent those kind of therapies at all.
    This is the issue of our time. This is the hill we are 
going to die on. It is too important. It is too important to 
protect our kids from this.
    In my very limited time--I have too limited--too much 
limited time, so I will wait for my colleagues to yield to me 
to ask questions, and I yield back. Thank you, Madam Chair--or 
Mr. Chairman.
    Mr. Guthrie. The gentleman yields back and the Chair 
recognizes--do you have anyone----
    Voice. Mr. Joyce.
    Mr. Guthrie. Dr. Joyce, you are recognized for 5 minutes.
    Mr. Joyce. Thank you for yielding, Mr. Chairman, to our 
witnesses for appearing here today.
    I think there's some subjects that we can agree on. 
Innovation. Innovation in healthcare is critical for producing 
better outcomes and improving the quality of care that patients 
receive. That is why I, like many others on this panel, are 
very concerned over the impact that the Inflation Reduction Act 
is having and will continue to have on future development of 
new treatments and new cures.
    It has been 40 years since the Orphan Drug Act was signed 
into law, and I am quite worried that the new misguided law 
will undermine one of the greatest incentives that we have 
seen, which has led to the development of over 600 novel 
therapies and cures, cures for diseases. However, there is 
still much work to be done.
    There are over 10,000 rare diseases, 95 percent of which 
lack an FDA-approved treatment. As enacted, the IRA 
disincentivizes post-approval research and development and 
seeks additional indications for promising treatments. This 
will acutely impact pediatric patients, who by their nature 
make up a much smaller subset of the total population.
    Dr. Thompson, thank you for being here from CHOP in 
Philadelphia. Is a decline in the research and development 
investment in pediatric research a concern, and what impact 
will that have long-term on the patients that you treat each 
and every day?
    Dr. Thompson. Thank you, Dr. Joyce. I think that there are 
some phenomenal opportunities to continue to make progress not 
only in pediatric health but also in the health of Americans 
overall when we have the opportunity to intervene, to diagnosis 
children and to treat them, largely coming from innovation. The 
ability to incentivize manufacturers to continue to stay in the 
space for rare diseases has been extraordinarily helpful.
    There have been challenges with continue--with the 
continuum to determining what will actually be paid for in 
terms of insurers, and I do think that that continues to be 
something that we need to be very mindful of because it is not 
entirely clear that the incentives that are there to 
manufacture the drugs are being paralleled with incentives to 
actually cover them in the clinical space.
    Mr. Joyce. Dr. Thompson, programs like Sickle Cell Disease 
and Other Heritable Blood Disorders Research, Surveillance, 
Prevention, and Treatment Act help prevent much-needed--help 
bring much-needed hope to the rare disease patient communities 
and help spur the research and development that will add new 
and improved treatments for these rare diseases. How can the 
lessons that we have learned from this program be used to 
support research and treatment for other rare diseases?
    Dr. Thompson. I think that the rare disease community is 
energized and is quite unified in trying to continue to learn 
from each other on how we can best go about that. Some of them 
are private-public partnerships. There are certainly any number 
of nonprofits that have been very active, especially family 
foundations, in bringing some of these things to our attention. 
Encouraging science and following the science and looking at 
ways to bring innovation from the bench to the bedside is, I 
believe, one of the things that many of our academic medical 
centers do quite well.
    I think without taking full advantage of the innovations, 
the breakthroughs that are occurring in sickle cell disease, if 
we don't take advantage of those in this patient population, it 
really does send a message to those who are suffering from 
other more rare diseases. And so I think we--I think embracing 
this in sickle cell should be a very positive message to all.
    Mr. Joyce. Thank you for that insight. Dr. Thompson, in the 
past few years alone there have been a number of new 
innovations in the cell and gene therapy space to cure, cure 
hematologic diseases. Dr. Thompson, can you speak to how 
impactful curative therapies for diseases could be for the 
patients that you treat and the impact that they have on their 
life to be cured of these diseases?
    Dr. Thompson. It has been absolutely extraordinary and 
very--and I have had the privilege of being part of the gene 
therapy efforts over the last 10 to 15 years in the 
hemoglobinopathy space. It has done two things. It--certainly 
for the individual patients who have been successful, it has 
been transformational. These are individuals who can now 
complete their educations, raise their families, maintain full 
employment, and can really live their best lives. And so for 
the individuals, without question.
    For me, it has also been a very hopeful one because many of 
these diseases are now diagnosed by newborn screening. And 
while I think in the past, many of these families were 
devastated when they thought that they were bringing home a 
perfectly healthy infant, yet to be told 2 weeks later that 
their child screened positive for something. Gene therapy that 
is being used right now in adults gives them tremendous hope 
that their children can not only live long lifespans, they can 
hopefully lead lifespans with far less disability than they 
would have in the past.
    Mr. Joyce. I think we can all conclude that innovation must 
be maintained and must be maintained as one of the cornerstones 
of American medical treatment. Thank you again, Dr. Thompson.
    And, Mr. Chairman, I yield.
    Mr. Guthrie. Thank you. The gentleman yields back. The 
Chair now recognizes the gentlewoman from Massachusetts, Mrs. 
Trahan, for 5 minutes.
    Mrs. Trahan. I thank the Chair. I am grateful to all the 
witnesses who came today prepared to talk about the bipartisan 
public health bills that are being covered in the hearing.
    We desperately need to advance proposals to address 
firefighter cancer rates, end Parkinson's, tackle the maternal 
health crisis, and so much more. Like so many of my colleagues, 
I am disappointed that the legislation focused on critical 
funding for our children's hospitals, and that is the one that 
is being politicized, which is why so many of the moms on this 
committee are speaking up.
    There are 59 children's hospitals who receive funding for 
graduate medical education from CHGME, just 1 percent of all 
hospitals in the country. But together they train more than 
half of our pediatricians and pediatric specialists across the 
country. Boston Children's Hospital in my home State is home to 
one of those training programs. In fact, the training program 
at Boston Children's receives no funding through Medicare, 
meaning it relies solely on CHGME funds to support their work 
with interns, residents, and fellows.
    The team at Boston Children's works around the clock to 
serve the children who travel from all over the country for 
specialized care. They deserve to feel supported by those of us 
in positions of power, not like that they are pawns in a 
political game. Pediatric providers are training, learning, and 
making contributions to advance and promote high-quality and 
effective care and treatment that every single one of us would 
want for our own child, if it was ever needed.
    Dr. McNamara, what are some of the challenges that 
pediatric care workforce is facing, and can you give us 
examples of the specialized care that would be disrupted if a 
partisan battle over reauthorization of CHGME continues?
    Dr. McNamara. So children need us more than ever. They have 
more complex health needs and mental health needs than they 
ever have. Part of that is because we are very good at 
providing advanced care that we have been developing over the 
years, and part of it is because of the current postpandemic 
climate.
    The examples of care that would be affected would be care 
for congenital heart disease, intensive care for sick kids, 
sick neonates, routine well care, dentistry. I could go on.
    Mrs. Trahan. I appreciate that. Boston Children's Hospital 
is home to the first pediatric and adolescent transgender 
health program in the United States. However, misinformation 
has repeatedly spread online suggesting the hospital performed 
gender-affirming genital surgeries on young children, when in 
reality, surgeries are only performed on consenting adults. But 
that hasn't stopped healthcare workers at Boston Children's 
from being subjected to threats and attacks.
    Threats and attacks, by the way, that are a direct result 
of a coordinated campaign designed to, and I am quoting a 
Conservative Political Action Conference speaker here, 
``eradicate transgenderism.'' And by inviting a witness to 
elevate that dangerous rhetoric in the United States Congress, 
the majority is allowing a target to be painted on the backs of 
some of our Nation's most vulnerable children and the 
healthcare professionals they rely on.
    Dr. McNamara, can you speak to the dangers of increased 
threats and attacks on our Nation's pediatric healthcare 
professionals, and do you think this intimidation undermines 
their ability to recruit specialists or continue providing a 
high level of care?
    Dr. McNamara. I absolutely do. I think if I was a medical 
student looking at the current political climate, it would feel 
overwhelming.
    Mrs. Trahan. I appreciate your candor, Doctor. Time and 
time again, I have heard my colleagues across the aisle discuss 
the urgent need to address the youth mental health crisis. But 
we can't do that if we ignore the fact that trans youth are 
suffering higher rates of mental illness, higher rates of 
suicide ideation, and higher rates of self-harm, a problem with 
a large body of medical literature demonstrating that, with 
support at home, in school, and in communities, coupled with 
access to gender-affirming care, trans youth do as well on 
mental health measures as their cisgender peers.
    We should be working to increase access to healthcare for 
all of our children, not to restrict the ability of children to 
define and express themselves. A ban on gender-affirming care 
is dangerous, it is misguided, and it is cruel, and it is a 
shame the Republicans are using what should be a bipartisan 
piece of legislation to contribute to the dangerous attack on 
our most vulnerable children. They deserve better.
    I yield back.
    Mr. Guthrie. The gentlelady yields back. The Chair now 
recognizes Dr. Dunn for 5 minutes for questions.
    Mr. Dunn. Thank you, Mr. Chairman. I appreciate the hard 
work this committee is putting in to ensure that critical 
public health programs do not lapse this year. I am pleased 
with the level of bipartisan collaboration shown to ensure that 
the programs that are aimed at improving childhood and maternal 
health serve our most vulnerable constituents. We are also 
supporting research to fight rare diseases.
    I do want to take a moment to echo the comments of my 
colleague, Dr. Burgess, regarding the Children's Hospital GME 
Program. I appreciate the bill put forth by my colleague, Mr. 
Crenshaw, to protect children from harmful gender-approving 
care and hormone therapy, and I understand that many children 
may feel immense peer pressure and psychological distress for 
many different reasons. These children need loving, caring 
parental involvement, they need emotional support, and they 
need highly specialized medical experts with their best 
interest at heart. It is a monumental decision to undertake 
gender transition surgery on a potentially fertile person. The 
radical race to embrace gender transition is undoubtedly 
harming some of our children.
    When considering pediatric GME, it is critical that we 
strike the right balance between banning appropriate treatments 
and procedures and properly equipping physicians with the 
skills and the knowledge they need to perform complex surgeries 
and inform the choices that patients and parents make. There 
actually are unique cases in which a baby is born with genetic 
disorders that cause truly ambiguous genitalia. This is a mix 
of male and female reproductive organs.
    As a urologist, I am very familiar with such cases. Medical 
surgical interventions may be needed to mitigate harmful side 
effects and even to save lives. In these cases, it is important 
that pediatric urologists have the specialized knowledge and 
the proper skillsets to make the best decisions with the 
patients, with the consent of their parents.
    I actually do not have any questions, Mr. Chair. I am 
willing to yield time to anybody on the panel. Mr. Crenshaw, I 
recognize you.
    Mr. Crenshaw. Thank you to my colleague, and I do have a 
few questions.
    You know, I want to say a few things first. We keep hearing 
this is a politicized issue, this is a manufactured culture 
war. I got to say, we aren't the ones who did that. We aren't 
the ones that came up with this radical new movement that is 
performing permanent physiological changes to children with no 
evidence of any benefits. We didn't start that, we are just 
trying to stop it because it is crazy.
    It is a contentious issue, which almost 70 percent of 
Americans oppose, so we are just saying here that taxpayer 
money shouldn't be used for it. That is all. This should not be 
that controversial of an issue.
    My questions are for Dr. McNamara. I just want to ask you, 
honestly, you are not concerned about the unknown effects of 
puberty blockers, hormones, and surgical interventions in kids, 
the long-term effects, you are not concerned about that?
    Dr. McNamara. Everything I have said here today comes from 
a place of deep honesty and conviction for the care that I 
provide in the community that I am a part of.
    Mr. Crenshaw. You have said that we have cherry picked 
data. How do you mean by--what--how do you mean that?
    Dr. McNamara. So it is very unscientific and flawed to pick 
a single study or a single statistic and to discuss it in 
isolation.
    Mr. Crenshaw. Totally agree.
    Dr. McNamara. Medical experts are able to talk about all of 
the evidence as a whole.
    Mr. Crenshaw. Totally agree. So it is good to look at 
systematic reviews, right, that is the gold standard of 
evidence when you are trying to understand whether something 
works or whether it doesn't. So the British Journal of Medicine 
looked at 61 systematic reviews with the conclusion that 
``there is great uncertainty about the effects of puberty 
blockers, cross-sex hormones, and surgeries in young people.'' 
The Journal of Endocrine Society came up with the same 
conclusion. Even the American Academy of Pediatrics. They all 
cite the lack of evidence.
    And so here is the thing: If you are doing a therapy, and 
it is, you know, temporary, whatever, fine, maybe let's try it, 
let's see if it works. But when you are talking about permanent 
physiological changes, do you not agree, just from an ethical 
standpoint, that you might want extremely strong evidence of 
the benefits? And there is no systematic review that states 
that there is strong evidence of benefits.
    Dr. McNamara. Sir, are you aware of how the quality 
evidence grading system works and how it is applied?
    Mr. Crenshaw. Yes. Yes, we read through it. That is why I 
am citing these journals. So which journal says something 
different? I am--we should have that debate. Tell me a journal 
that has done systematic reviews that cites different evidence, 
that cites strong evidence for benefits of these therapies.
    Dr. McNamara. The standards of care were developed based on 
extensive----
    Mr. Crenshaw. You are not telling me any journal, you are 
not telling me any study. Don't say standards of care----
    Dr. McNamara. But that is not what--yes. So----
    Mr. Crenshaw. Tell me one.
    Dr. McNamara. The standards of care.
    Mr. Crenshaw. The standards of care. That is----
    Dr. McNamara. Yes, standards of care.
    Mr. Crenshaw [continuing]. Not a journal, that is not a 
study. That is not an organization, that is not an institution. 
You are just saying words. Name one study.
    I am out of time. I yield back.
    Mr. Guthrie. And the gentleman's time is expired. Mr. Dunn 
yields back. The Chair now recognizes Dr. Miller-Meeks for 5 
minutes for questions.
    Mrs. Miller-Meeks. Thank you, Mr. Chair, and I thank our 
witnesses for being here and testifying before the committee 
today.
    I am proud to see my bill, H.R. 3226, PREEMIE 
Reauthorization Act, included in today's hearing. And I thank 
Ranking Member Eshoo as well as Representative Kelly, Blunt 
Rochester, Burgess, and Kiggans for their hard work on the 
legislation. As a mother and a physician, I understand the 
harmful health implications of preterm birth and recognize the 
importance of public health programs like PREEMIE which seek to 
address the root causes. Also because I was a director of the 
Department of Public Health.
    In 2021, Iowa mothers gave birth to almost 3,700 preterm 
babies, which represented 10 percent of all births in the State 
that year. Not only do preterm births pose great health risks 
to the mother and her baby, but they are close--very costly to 
the healthcare system, as was alluded. Over 28 percent of 
infant deaths are preterm related, and the average cost 
associated with preterm births in Iowa is $50,000--$58,000.
    Dr. Cherot, in your written testimony, you state that 
almost two-thirds of pregnancy-related deaths are preventable 
and that preterm birth rates worsened in 38 States between 2018 
and 2019. Can you please explain how reauthorizing PREEMIE will 
help reduce those rates and how funding will be used?
    Dr. Cherot. So first, the financial impact of preterm birth 
on the U.S. economy and families. Medicaid pays for 40 percent 
of all deliveries, and an estimated 40 percent of medical costs 
associated with preterm birth has a significant impact on both 
Federal and State budgets. Our--what we are trying to advocate 
for here is more research to go into more solutions that will 
solve for the preterm problem in this country that you just 
alluded to or highlighted and have dealt with in the neonatal 
intensive cares across this country. And the point of this is 
to be able to collect that data to translate those into real 
actions.
    Mrs. Miller-Meeks. Thank you.
    I would also like to speak in support of Congressman 
Crenshaw's legislation to reauthorize Children's Hospital GME. 
The Republicans wish to reauthorize this, it is the parties on 
the other side of the aisle that wish not to.
    I know firsthand that a physician's training is a lengthy 
and expensive process, which is why renewing CHGME to ensure 
that there is sufficient supply of pediatricians to meet demand 
is so important. The timely reauthorization of this program 
through 2028 will continue a legacy of over 20 years of 
supporting our healthcare providers. However, I am also 
supportive of a ban on funding for hospitals that furnish 
puberty blockers, hormone therapies, and surgeries for the 
purpose of altering biological genitalia to minors.
    So, Dr. McNamara, is an XY chromosome assigned at birth?
    Dr. McNamara. I am sorry, I don't understand the nature of 
your question.
    Mrs. Miller-Meeks. Simple question. Is an XY chromosome 
assigned at birth?
    Dr. McNamara. We often don't do routine chromosome testing 
on infants.
    Mrs. Miller-Meeks. So an XY chromosome would not be 
assigned at birth, nor would an XX chromosome, although you say 
that sex is assigned at birth. There is a lack of scientific 
evidence regarding the effectiveness of these medical 
interventions, especially among minors, which is why countries 
in Europe, such as Denmark, Britain, Sweden, have described 
treatments as experimental and are urging doctors to proceed 
with caution and why they have changed their guidance.
    The purpose of healthcare is to treat and heal, and it is 
not of interest--at the expense of physical and mental well-
being of patients.
    What evidence, Dr. Grossman, do we have that the thriving 
Dr. McNamara talks about is because of hormones or surgery and 
psychotherapy, family support, regression to the mean, placebo 
effect, or some other confounding variable? After all, there 
have been no randomized controlled trials. Have there been 
randomized controlled controls, Dr. McNamara?
    Dr. Grossman. There have not. Randomized controlled trials 
are what are the gold standard. That is what we are always 
looking for in medicine. We do not have those kind of studies.
    As you said, there are variables, confounding variables 
that can interfere if a child is going through these gender-
affirming cares, so-called. The child may also be getting 
psychotherapy. The family may be getting support. How do we 
know that the improvement on the other side is due to the 
hormones or the surgeries or the psychological support?
    Mrs. Miller-Meeks. Yes. Thank you. And I think to say that 
the Federal Government is not already involved in healthcare is 
either naive or disingenuous. We saw that throughout the 
pandemic, that Federal and State governments were both involved 
in the doctor-patient relationship.
    As a veteran, I defended the right--the constitutional 
rights of Americans. As a doctor, I swore to do no harm because 
I care about the physical and mental health of your children as 
much as I do my own children.
    Mr. Guthrie. Thanks----
    Mrs. Miller-Meeks. I support restricting Federal funding 
for experimental care----
    Voice. Time.
    Mrs. Miller-Meeks [continuing]. That is permanent and 
irreversible in minors.
    Mr. Guthrie. The gentlelady's time is expired.
    Mrs. Miller-Meeks. Thank you, I yield my time.
    Mr. Guthrie. The Chair now recognizes Mr. Pence for 5 
minutes.
    Mr. Pence. Thank you, Chairman Guthrie and Ranking Member 
Eshoo.
    I would like to speak in support of the Action for Dental 
Healthcare Act of 2023. Across my district, dental 
professionals continually communicate to me the impacts they 
are feeling from workforce shortages. Healthcare facilities, 
including dental practices, are struggling to maintain existing 
staff and rising salaries, let alone find enough qualified 
individuals to fill open positions. Universities are also 
straining to maintain the necessary pipeline of our next 
generation's health professionals.
    As we look to reauthorize dental workforce programs through 
the Action for Dental Health Act, it is important we ensure HHS 
is prepared to support the growing demand for dental 
professionals across the country and my Hoosier State.
    I would like now to yield time--the rest of my time to my 
colleague Congressman Crenshaw, a champion for our young 
children.
    Mr. Crenshaw. I thank the gentleman.
    And, look, I just want to make a few more points. And I 
want to run everyone through this thought experiment. So, you 
know, my daughter is going to grow up with a father with one 
eye, and at some point she might say, you know, I want one eye, 
right, I identify as somebody with one eyeball--which by the 
way, is far less important than your gender, just 
physiologically speaking.
    And so if I take her to the doctor and I say, ``Can you 
just enucleate that eye for us because she identifies as a one 
eye--she wants to be just like her dad,'' what would the 
doctors say? They would say, ``You are crazy, and I am going to 
have you arrested.'' That is what--well, that is what they 
should say. And this is for a physiological intervention that 
is far less important than your actual gender and your 
reproductive organs. We have to stop this madness. This has 
gone too far.
    You know, I asked before about what evidence is there that 
there is benefit for these so-called standards of care. I mean, 
anyone can say that they have a standard of care, but it has to 
be based on some kind of evidence and research. And when you 
have done systematic reviews--which is, again, is the gold 
standard for how you come to a conclusion within the scientific 
community, systematic reviews of 61 other systematic reviews--
and you find little to no evidence that there's benefits for 
this, maybe you just press pause.
    Maybe you just press pause. Because if we are doing 
permanent physiological interventions to children that have--
permanently disfiguring them for some hope of a benefit that is 
not conclusive, then maybe we should press pause. Like, that is 
all we are saying. Press pause.
    And actually that is--and actually it is even less than 
that. All we are saying is let's not put taxpayer money toward 
it, right. This is no different than how this Congress deals 
with the Hyde Amendment. This is a controversial issue. 
Abortion is a controversial issue, and so we say, ``Look, we 
disagree on this, so let's make sure we don't put taxpayer 
funding toward it.'' That is all this bill is.
    Let's not put taxpayer funding towards something that is so 
obviously unproven and contentious. Actually, I don't even 
think it is--it is really not that contentious. Seventy percent 
of Americans oppose it, so it is actually the American people 
are pretty much on the side of not doing this, or at least 
pressing the pause button.
    Dr. Grossman, you are a child psychiatrist. Can you expand 
upon the profound lack of clinical reviews and the long-term 
impacts of these treatments: puberty blockers, hormones, and 
surgeries?
    Dr. Grossman. Well, yes, as I said, we don't have the kind 
of studies that we would like. And I think it is very important 
for people to understand that when we talk about standards of 
care and we talk about guidelines and all the various 
associations that have come out for gender-affirming care and 
about politics and partisanshipness, those organizations 
themselves are rife with politics. They are permeated with 
politics. The American----
    Mr. Crenshaw. Can you expand that? Just tell us how those 
activists have pressured dissenting voices in this field.
    Dr. Grossman. Well, yes, I just interviewed a number of 
doctors for my book--pediatricians, endocrinologists--who 
reported back to me on the fact that when they tried to speak 
up and have panel discussions or presentations that challenged 
gender-affirming care at the American Academy of Pediatrics or 
at the Endocrine Society, they are simply not given that 
opportunity. Even people, you know, who have written--writing 
articles, the articles are turned by a lot of journals. People 
have to understand that politics has--medicine, unfortunately, 
is permeated with politics at this point.
    Now, ideally, we wouldn't be stepping in. Who wants the 
Government stepping in between doctors and parents and 
children? Of course we ideally don't want that. But when there 
is something that is so wrong that is going on, then I think we 
have to.
    Voice. Time.
    Mr. Crenshaw. Thank you.
    And I yield back to Mr. Pence.
    Voice. Time. Time.
    Mr. Guthrie. Yes, Mr. Pence yields back. The Chair now 
recognizes--seeing that all members of the subcommittee have 
been recognized, the Chair now recognizes Ms. Schakowsky for 5 
minutes for questions.
    Ms. Schakowsky. Thank you for allowing me to waive on to 
this--to the subcommittee.
    I just want to briefly begin by talking about children's 
hospital--the medical education programs for children's 
hospitals. I--in Chicago, I have Lurie Children's Hospital, 
which is such a fabulous institute and the largest medical 
provider in Illinois but is very concerned because of the 
disparity between what is given to other hospitals and the 
children's teaching hospitals. And I just wanted to mention 
that because we do rely so much on that.
    But I really now feel obligated and it is a privilege to 
now talk about--as the only parent, I think, in this room, or 
grandparent, of a trans young man, someone whose life has been 
enormously improved because of his ability. Born as a girl but 
finding his true self now as a young man who is living the life 
that he--that belongs to him. He is now graduated from college, 
he is teaching school, he is living with his girlfriend, and 
fortunately in a place where he has the opportunities to get 
the care that he needs and has throughout the period that he 
needed it.
    And so, Dr. McNamara, I want to thank you first of all for 
your voice, and I wondered if you could just enumerate some of 
the other falsehoods that we are hearing and that I have 
experienced now in my family's lifetime.
    Dr. McNamara. Thank you. So first of all, regarding 
standards of care, that is not just a causal term. The 
standards of care that outline how gender-affirming care should 
proceed for people of all ages, including adolescents, have 
been published in reputable journals. The Journal of the 
Endocrine Society has published their extensively vetted 
guidelines, which they have issued several times after 
reexamining the evidence.
    The World Professional Association for Transgender Health 
issued the eighth edition of the Standards of Care, which is 
based on peer review of hundreds of global experts who 
basically perform systematic reviews in partnership with Johns 
Hopkins. The AAP has also issued statements that issue kind of 
practice guidelines that are taken very seriously in our 
community.
    Nowy, I want to address the low-quality-evidence argument 
that comes up a lot, and it is critical that we all understand 
here today that that is a technical term and that when it is 
used for public consumption, it can be quite confusing. There 
are ways to grade evidence using a very specific rubric where 
the number of study participants, the length of followup, et 
cetera is assessed. In medicine, we recognize that all clinical 
care is different, all clinical research is different, and the 
practicalities of conducting studies are different.
    Low-quality evidence means that there is a basis of 
evidence, and it often informs strong recommendations for care.
    Ms. Schakowsky. Thank you for that. And I also want to see 
if you could actually help us understand the kind of work that 
is done with families. It--you would think that these children 
are snatched away and taken someplace and done--but isn't there 
a whole process that patients and their families go through, 
and if you could tell us about that.
    Dr. McNamara. Yes, ma'am. Well, oftentimes the care begins 
with long conversations that take place over months and months 
where families hear about all of their options. Parents hear 
about the risks and the benefits, they hear about various 
options, they ask lots of questions, and the young person gets 
mental health support.
    Ms. Schakowsky. And let me--and, finally, let me just say, 
if you could speak to the importance of having both behavioral 
healthcare and also the medical needs of these kids, how both 
are so important. It is implied that it is only, you know, 
the----
    Dr. McNamara. Gender dysphoria is real and it needs to be 
diagnosed by a specialist. That is the standard of care in this 
country. Medical care does not proceed unless a mental health 
specialist has diagnosed this condition.
    Ms. Schakowsky. Thank you.
    Mr. Guthrie. Thank you.
    Ms. Schakowsky. I yield back.
    Mr. Guthrie. The gentlelady's time has expired and yields 
back. The gentleman from New York is recognized for 5 minutes.
    Mr. Tonko. Thank you, Mr. Chair. I thank you and our 
Ranking Member Eshoo for the opportunity to waive on. I thank 
you for including the National Plan to End Parkinson's Act as a 
part of this hearing. In Congress, I have made helping those 
with neurological disorders one of my top priorities. I have 
long led efforts related to the other top neurological disorder 
facing Americans, which is Alzheimer's. I am proud to expand my 
championship to facing Parkinson's as well.
    Currently, more than 1 million people in the U.S. live with 
Parkinson's disease, and there are no treatments to cure, 
prevent, or significantly slow down its progression. 
Parkinson's is the second-most common neurological disease and 
is fortunately--unfortunately growing, and growing fast. Nearly 
60,000 Americans are diagnosed every year, and the disease is 
estimated to cost the U.S. $52 billion annually. With the 
number of Americans diagnosed with Parkinson's disease expected 
to increase as the population ages, the cost to the U.S. 
economy is also expected to balloon to nearly $80 billion every 
year by 2037.
    I thank my good friend and colleague, Gus Bilirakis, for 
working on the National Plan to End Parkinson's Act with me. It 
is an honor to work with him on this, and I know how much it 
means to him personally, and I thank him for the relentless 
work as we work together to push this forward.
    Our bipartisan, no-cost legislation will for the first time 
unite the Federal Government in a mission to cure and prevent 
Parkinson's, alleviate financial and health burdens on American 
families, and reduce government spending over time. This 
pioneering legislation is greatly needed.
    I also thank Mr. George Manahan for joining us here today--
--
    Mr. Manahan. Sure.
    Mr. Tonko [continuing]. And bravely sharing your journey 
with Parkinson's. By speaking here today, you do give a face to 
Parkinson's. As Mr. Manahan noted, we all know someone with 
this devastating disease. I first learned about Parkinson's 
from a friend who suffered with it, and recently my good friend 
and colleague, Congresswoman Jennifer Wexton, was diagnosed 
with Parkinson's. I thank the Congresswoman for showing another 
face of Parkinson's and bravely sharing publicly her journey.
    With that in mind, I would like to share a brief message 
from Congresswoman Wexton, and I quote: ``As many of you know, 
earlier this year on World Parkinson's Disease Day, I shared 
that I myself have been diagnosed with Parkinson's disease, or 
PD. Over the past several months, I have been touched by the 
hundreds of messages of appreciation and hope that I have 
received from people who suffer from PD, but even more often 
from their loved ones and caregivers.
    ``A diagnosis of Parkinson's disease affects not only those 
of us who suffer from the disease itself but all of the many 
people in our lives who love us and want us to be well again. 
Parkinson's is the fastest growing brain disease worldwide and 
is estimated to affect at least 14 million people by 2040. PD 
is a progressive neurodegenerative disease, and although there 
are things we can do to slow its progression, at this time 
there is no cure.
    ``Eventually, many of us who have Parkinson's will be 
unable to walk, talk, or even feed ourselves. We will require 
extensive and expensive institutional or in-home care, the cost 
of which will likely be borne primarily by U.S. taxpayers. 
Research has shown that, although heritability is a factor, PD 
is largely caused by environmental toxins and it can therefore 
be prevented if adequate precautions are taken.
    ``In addition, great strides are being made to identify 
genetic markers of Parkinson's, which we believe will lead to 
identifying variations of PD that will allow researchers to 
develop targeted treatments that will help alleviate symptoms 
and improve quality of life for those with the disease and slow 
or even halt its progression. By bringing together key 
stakeholders to build the national plan to prevent and cure 
Parkinson's, this bill is taking a critical and historic step 
for the millions of Americans with Parkinson's and their 
families just like mine. I urge you to advance this critical 
bipartisan legislation.''
    And I end there with Jennifer's quote. I could not agree 
more. I understand that receiving a Parkinson's diagnosis is 
truly devastating for individuals and their loved ones. It is 
incumbent upon Congress to ensure Americans know they will be 
supported during this frightening and life-altering time. Our 
legislation does just that. My hope is that this bill, when 
signed into law, will do for Parkinson's what national plan did 
for Alzheimer's and bring together coordination, care, and 
research all to help those with Parkinson's as well as their 
loved ones.
    So to Mr. Manahan, I again thank you and ask, what would 
this legislation mean for those living with Parkinson's, and 
what about their families and their friends?
    Mr. Manahan. It would give us hope. And really we haven't 
had hope until just recently. We have found a biomarker which 
can detect Parkinson's disease at a very early stage. So, you 
know, for those people who are left who have Parkinson's, this 
would give us hope that we can find a solution working together 
hand in hand.
    Mr. Tonko. And I would think the investment and 
coordination factors of the legislation would provide for more 
effective treatments.
    Mr. Manahan. Yes.
    Mr. Guthrie. Thank you.
    Mr. Tonko. With that, I yield back.
    Mr. Guthrie. Thank you. The gentleman----
    Voice. [Indiscernible.]
    Mr. Guthrie. Thank you. Absolutely. The gentleman yields 
back. The Chair now recognizes Ms. Barragan from California for 
5 minutes.
    Ms. Barragan. Thank you, Mr. Chairman. I want to echo some 
of my colleagues' comments about the importance of the 
Children's Graduate Medical Education Program and how critical 
it is. I was recently in my congressional district where I had 
an opportunity to meet with the Long Beach Memorial Care to 
hear about the importance that it has and why we need to 
continue to support it and fund it.
    I am highly disappointed in my colleagues across the aisle 
who are basically holding this bill hostage and this funding 
hostage by, you know, putting in provisions that are just 
unacceptable, and so it is really unfortunate, and I just 
wanted to echo that concern that we continue to work to get 
this funded and taking out some of these harmful provisions.
    I want to kind of follow up on my colleague, Representative 
Tonko. Mr. Manahan, I found your testimony to be very powerful, 
particularly on your optimism that we can develop a national 
plan to end Parkinson's disease. I agree we need to use every 
available resource to fight Parkinson's disease. It is costing 
patients their lives and significantly increasing our 
healthcare costs with an estimated $52 billion in direct and 
indirect costs to society. And now that we have an accurate 
biomarker that can detect Parkinson's disease before the first 
symptoms appear, innovation is urgently needed to find a cure.
    Now, as my colleague said, we all know somebody who has 
Parkinson's. My father had Parkinson's for most of my youth. My 
father died when I was 23 years old, and for most of my memory 
he was shaking and I would have to sit next to him and hold his 
hand or try to hold his arms because I wanted the shaking to 
stop. I didn't know any better, I was a kid, and he and I, we 
watched baseball games together.
    And so it has been a personal issue for me and something I 
know we need to continue to champion. That is why I am a strong 
supporter of H.R. 2365, the National Plan to End Parkinson's 
Act, which will create an advisory council to prevent and cure 
Parkinson's.
    In your testimony you speak about the lack of services 
available for people with Parkinson's. How can the Federal 
Government support efforts to build out a stronger public 
health and caregiving infrastructure to support patients and 
families living with Parkinson's disease?
    Mr. Manahan. Well, it is interesting you mention that 
because, you know, unlike Alzheimer's, we don't have 
Parkinson's services on a State-by State basis. So when I was 
diagnosed, I didn't know anybody with Parkinson's and there was 
no support groups, so we started those in West Virginia. We 
started a 5K that raised money for the Michael J. Fox 
Foundation, we raised $500,000. We have support groups, free 
exercise classes. So we did it ourselves. But there has to be a 
way that State by State there has to be some continuity of care 
and continuity of support.
    Ms. Barragan. Right. Well, thank you for your advocacy, for 
starting the support group. When I was--I remember when Michael 
J. Fox came out with his diagnosis, I thought, you know, oh, 
this is going to be some hope, there is going to be a 
foundation that is going to invest in this. But certainly they 
can't do it alone, and so it is critical that Congress also 
help out. And so I want to thank my colleagues who are working 
on that issue.
    I want to turn to maternal health. Dr. Cherot, would you 
please explain how maternal mortality review committees align 
and/or collaborate with perinatal quality collaboratives to 
identify opportunities to prevent pregnancy-related deaths?
    Dr. Cherot. Sure, happy to. And I would say the California 
PRQ is a big success story, especially around preterm birth, 
and March of Dimes has been collaborating with them for some 
time.
    Fundamentally, the PQCs do the work. And so what they do 
are--State or multistate, what they tend to do is to--are their 
networks that improve quality and outcomes. So they have 
multiple stakeholders, whether it is clinicians, hospitals, 
communities that work together and fundamentally take what the 
MM--the recommendations from the committees that--I can't--now 
I am so tired by the end of the day--MMRCs, they take that and 
fundamentally drive the best outcomes, right. So they take the 
data, turn around and say, ``This is what we would recommend'' 
and do the hard work.
    Ms. Barragan. Great, thank you so much.
    With that, I yield back.
    Mr. Guthrie. Thank you. Thank you so much. And so many of 
us have families come tell their stories to us, and it is so 
powerful to hear stories, and thanks for sharing because it--we 
have--Congress is made up of America, and so we have the same 
stories, and so this is important to do.
    Well, thanks. That has concluded all of our Members and 
people who have waived on that would like to ask questions. 
Thanks for your testimony and your willingness to sit here so 
long and answer so many questions. And it is important and it 
informs our work, and we really appreciate the opportunity for 
all of you to be here today.
    To do a little committee business, we have a list of--and 
actually, Representative Wexton's statement was read from, but 
she had submitted that for the record too, so it is part of it 
as well.
    But I ask unanimous consent to insert in the record the 
documents included on the staff hearing documents list that 
have been reviewed by both sides.
    Seeing no objection, that will be an order.
    [The information appears at the conclusion of the hearing.]
    Mr. Guthrie. Again, and thanks so much. And there will be 
other questions. I know you all sat here for a long time. There 
could be other----
    Ms. Eshoo. Chairman.
    Mr. Guthrie [continuing]. Questions that Members could 
submit.
    Ms. Eshoo. May I just add something?
    Mr. Guthrie. Yes. Yes.
    Ms. Eshoo. Yes. I would just like to--Mr. Manahan, you are 
the only one that I didn't get to speak to. Thank you. Thank 
you to each one of you. Whether I agree or disagree, this is an 
important place, it is the People's House.
    And, Mr. Manahan, I want to add to your envelope of hope 
because the Congress did in the last session toward the end of 
the session pass legislation creating a new, very small, limber 
agency that is designed to take on the death sentences of 
diseases, and Parkinson's is one of them. So I want you to know 
that, you know, there are a lot of Members that poured their 
hearts and souls into that, understanding, you know, that if it 
is pancreatic cancer, it is a death sentence, if it is 
Parkinson's, if it is, you know, the cancers.
    So I just want to--I wanted to share that with you.
    Mr. Manahan. Thank you, Congresswoman.
    Ms. Eshoo. So thank you for being here. You are very 
courageous.
    Mr. Manahan. Thank you.
    Ms. Eshoo. You are very courageous.
    And, Kevin, I am going to write the question to you. I 
can't believe that we did legislation, it became law, and the 
CDC didn't do a damn thing with it for almost 5 years, and now 
we are reauthorizing it. Go figure.
    Mr. Guthrie. We're going to----
    Ms. Eshoo. Ladies, thank you.
    Mr. Guthrie [continuing]. Have oversight of that, I can 
guarantee you that.
    Ms. Eshoo. Yes. Yes, good.
    Mr. Guthrie. Thank you so much.
    Ms. Eshoo. OK.
    Mr. Guthrie. So I appreciate it. But I--there will be 
written questions. I will remind all the Members that they have 
10 business days to submit questions for the record, and I ask 
the witnesses to respond promptly. Members should submit their 
questions by the close of business on June 28th.
    Again, thank you for your patience. We appreciate you being 
here. And the subcommittee is adjourned.
    [Whereupon, at 2:00 p.m., the subcommittee was adjourned.]
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