[Senate Hearing 116-39] [From the U.S. Government Publishing Office] S. Hrg. 116-39 DRUG PRICING IN AMERICA: A PRESCRIPTION FOR CHANGE, PART II ======================================================================= HEARING before the COMMITTEE ON FINANCE UNITED STATES SENATE ONE HUNDRED SIXTEENTH CONGRESS FIRST SESSION __________ FEBRUARY 26, 2019 __________ [GRAPHIC(S) NOT AVAILABLE IN TIFF FORMAT] Printed for the use of the Committee on Finance ________ U.S. GOVERNMENT PUBLISHING OFFICE 37-143 PDF WASHINGTON: 2019 COMMITTEE ON FINANCE CHUCK GRASSLEY, Iowa, Chairman MIKE CRAPO, Idaho RON WYDEN, Oregon PAT ROBERTS, Kansas DEBBIE STABENOW, Michigan MICHAEL B. ENZI, Wyoming MARIA CANTWELL, Washington JOHN CORNYN, Texas ROBERT MENENDEZ, New Jersey JOHN THUNE, South Dakota THOMAS R. CARPER, Delaware RICHARD BURR, North Carolina BENJAMIN L. CARDIN, Maryland JOHNNY ISAKSON, Georgia SHERROD BROWN, Ohio ROB PORTMAN, Ohio MICHAEL F. BENNET, Colorado PATRICK J. TOOMEY, Pennsylvania ROBERT P. CASEY, Jr., Pennsylvania TIM SCOTT, South Carolina MARK R. WARNER, Virginia BILL CASSIDY, Louisiana SHELDON WHITEHOUSE, Rhode Island JAMES LANKFORD, Oklahoma MAGGIE HASSAN, New Hampshire STEVE DAINES, Montana CATHERINE CORTEZ MASTO, Nevada TODD YOUNG, Indiana Kolan Davis, Staff Director and Chief Counsel Joshua Sheinkman, Democratic Staff Director (ii) C O N T E N T S ---------- OPENING STATEMENTS Page Grassley, Hon. Chuck, a U.S. Senator from Iowa, chairman, Committee on Finance........................................... 1 Wyden, Hon. Ron, a U.S. Senator from Oregon...................... 3 WITNESSES Gonzalez, Richard A., chairman and chief executive officer, AbbVie Inc., North Chicago, IL................................. 6 Soriot, Pascal, chief executive officer, AstraZeneca, Wilmington, DE............................................................. 8 Caforio, Giovanni, M.D., chairman of the board and chief executive officer, Bristol-Myers Squibb Company, New York, NY.. 9 Taubert, Jennifer, executive vice president, worldwide chairman, Janssen Pharmaceuticals, Johnson & Johnson, New Brunswick, NJ.. 11 Frazier, Kenneth C., chairman and chief executive officer, Merck and Company, Inc., Kenilworth, NJ.............................. 12 Bourla, Albert, DVM, Ph.D., chief executive officer, Pfizer, New York, NY....................................................... 14 Brandicourt, Olivier, M.D., chief executive officer, Sanofi, Bridgewater, NJ................................................ 15 ALPHABETICAL LISTING AND APPENDIX MATERIAL Bourla, Albert, DVM, Ph.D.: Testimony.................................................... 14 Prepared statement........................................... 63 Responses to questions from committee members................ 66 Brandicourt, Olivier, M.D.: Testimony.................................................... 15 Prepared statement........................................... 134 Responses to questions from committee members................ 144 Caforio, Giovanni, M.D.: Testimony.................................................... 9 Prepared statement........................................... 474 Responses to questions from committee members................ 475 Frazier, Kenneth C.: Testimony.................................................... 12 Prepared statement........................................... 495 Responses to questions from committee members................ 497 Gonzalez, Richard A.: Testimony.................................................... 6 Prepared statement........................................... 527 Responses to questions from committee members................ 528 Grassley, Hon. Chuck: Opening statement............................................ 1 Prepared statement........................................... 704 Soriot, Pascal: Testimony.................................................... 8 Prepared statement........................................... 705 Responses to questions from committee members................ 713 Taubert, Jennifer: Testimony.................................................... 11 Prepared statement........................................... 839 Responses to questions from committee members................ 845 Thune, Hon. John: Submission, 340B Health...................................... 1,053 Wyden, Hon. Ron: Opening statement............................................ 3 Prepared statement........................................... 1,054 Communications AARP............................................................. 1,057 American Society of Health-System Pharmacists.................... 1,058 Coalition for Affordable Prescription Drugs...................... 1,062 George, Linda.................................................... 1,064 Huszagh, Robin K................................................. 1,065 Interfaith Center on Corporate Responsibility.................... 1,066 National Association of Free and Charitable Clinics.............. 1,070 National Business Group on Health................................ 1,072 National Coordinating Committee for Multiemployer Plans.......... 1,076 Oxfam America.................................................... 1,078 Patients for Affordable Drugs Now................................ 1,080 Pharmaceutical Care Management Association....................... 1,084 Raffle, Debra L.................................................. 1,089 Ricci, Laura T................................................... 1,091 Rowland, Rhonda.................................................. 1,099 DRUG PRICING IN AMERICA: A PRESCRIPTION FOR CHANGE, PART II ---------- TUESDAY, FEBRUARY 26, 2019 U.S. Senate, Committee on Finance, Washington, DC. The hearing was convened, pursuant to notice, at 10:15 a.m., in room SD-215, Dirksen Senate Office Building, Hon. Chuck Grassley (chairman of the committee) presiding. Present: Senators Roberts, Enzi, Cornyn, Thune, Isakson, Portman, Toomey, Scott, Cassidy, Lankford, Daines, Young, Wyden, Stabenow, Cantwell, Menendez, Carper, Cardin, Brown, Bennet, Casey, Whitehouse, Hassan, and Cortez Masto. Also present: Republican staff: Chris Allen, Senior Advisor for Benefits and Exempt Organizations; Brett Baker, Health Policy Advisor; Stuart Portman, Health Care Policy Advisor; Karen Summar, Chief Health Policy Advisor; and Jeff Wrase, Deputy Chief of Staff and Chief Economist. Democratic staff: Michael Evans, General Counsel; Peter Gartrell, Investigator; Matt Kazan, Senior Health Policy Advisor; Kristen Lunde, Winston Fellow; and Joshua Sheinkman, Staff Director. OPENING STATEMENT OF HON. CHUCK GRASSLEY, A U.S. SENATOR FROM IOWA, CHAIRMAN, COMMITTEE ON FINANCE The Chairman. I want to welcome and to thank our witnesses for being here. We know that you put a lot of hard work into it, and staffs and the Senators have done the same thing. The information that these witnesses will share will help inform the committee as it addresses the issues of high prescription drug prices. America has a problem with the high cost of prescription medicines. Whether it is about EpiPen, insulin, or other prescriptions, in the thousands of letters that I have received, Iowans have made clear that high drug prices are hurting. I have heard from people about skipping doses of their prescription drugs to make them last until the next paycheck. Of course, I am not a doctor, but rationing one medicine does not sound like the safe prescription for health and wellness that Americans want. Others have told me about leaving their prescription on the pharmacy counter because it costs too much. There is no question that researchers and doctors have developed treatments and cures for diseases where there were once no such cures or treatments. And such innovations take time and money. I think all of us at this table--and most people who are not at this table--if they study at all the pharmaceutical industry and the FDA process, they know it takes time and money. But we are all trying to understand the sticker shock that many drugs generate, especially when some of these drugs have been around for a long, long time. There is a balance then between incentivizing innovation and keeping prices affordable for consumers and taxpayers. And the taxpayers are involved, because the Federal Government is a great purchaser of drugs through a lot of health programs. Like all systems, things can get out of balance. The good news is that we are here to discuss solutions. And we thank all of you for cooperating with us in that effort today. In fact, we are here today thanks to a system of checks and balances that is within our Constitution. Congress has a constitutional responsibility to be a meaningful check on the spending of taxpayers' money. That responsibility includes not just holding hearings, but also holding the private sector and the government accountable through oversight, just like a doctor. That doctor has to properly diagnose a disease before it can be treated. Congress needs to understand what is going on in the drug pricing supply chain in order to respond in a measured and effective way. As part of that fact-finding, as of the last Friday Ranking Member Wyden and I launched an inquiry into the high cost of insulin. This hearing is not about scapegoating any one group regarding high drug costs. That is why we are holding a series of bipartisan hearings on this issue. Without a doubt, drug pricing is a complex issue. But I think we should also be asking whether or not it is too complex or whether it should be so complex. We cannot allow anyone to hide behind the current complexities to shield the true cost of drugs. And we should not turn a blind eye to industry practices that thwart laws and regulations designed to promote competition and generic drug entries into the marketplace. Health and Human Services Secretary Alex Azar, FDA Commissioner Scott Gottlieb, and the Federal Trade Commission have identified a number of tactics that undermine competition, like withholding samples, pay-for-delay, product hopping, and rebate bundling. And that just names a few. While these agencies are taking enforcement action or looking at regulatory changes, we here in Congress are exploring legislative options to deter companies from engaging in these practices that keep drug prices high for patients. Today we expect open, honest answers from the pharmaceutical industry to figure out how we got where we are today and to see what ideas they have to make things better. One of the first things that we need to talk about is pretty simple: list price. Now you folks are probably going to tell us it is not that simple. Secretary Azar has said that pharmaceutical companies believe that the list price is meaningless. In fact, some of your testimony today will echo that. However, for a patient taking a drug that has no competition, the list price then becomes very meaningful. For seniors on Part D or paying coinsurance as a percentage of list price, then for that person, list price is very meaningful. For people who have high- deductible plans and pay thousands of dollars towards the list price, then for those people, the list price is very meaningful. For pharmacy benefit managers, providing drugs with a high list price can be more attractive than providing a less expensive drug. Therefore, for the taxpayers then, the list price becomes very meaningful. We have all seen the finger-pointing. Every link in the supply chain has gotten skilled at that finger-pointing. But like most Americans, I at least--I think like most members of Congress--am sick and tired of the blame game. It is time then for solutions. One way or another, we are going to get some clarity. The American people deserve straight answers and real solutions. On that note, I want to remind each of our witnesses that it is a crime under title 18, section 101 to provide false testimony to Congress. I thank you all for coming. [The prepared statement of Chairman Grassley appears in the appendix.] The Chairman. Senator Wyden? OPENING STATEMENT OF HON. RON WYDEN, A U.S. SENATOR FROM OREGON Senator Wyden. Thank you very much, Mr. Chairman. And I just want to note, at the outset, our focus on bipartisanship. We began that with our effort to go after price gouging with hepatitis C. Recently we have gone after manufacturers ripping off Medicaid. You noted our investigation to look at insulin prices that just soar and soar and soar some more. So I just very much appreciate the fact that we are tackling this in a bipartisan way. Colleagues, prescription drugs did not become outrageously expensive by accident. It is not the result of a system too complicated for Americans to understand. Drug prices are astronomically high because that is where pharmaceutical companies and their investors want them. The brakes have come off pharmaceutical pricing, and American families are hurtling along in the passenger seat terrified about what comes next. Today the committee is going to hear about uplifting stories and miracle cures. Yet it is morally repugnant when patients cannot afford those miracles. It is morally repugnant when ailing patients are forced to choose between filling the next prescription or putting food on the table because they cannot afford both. It is morally repugnant when patients are forced to skip doses. Pharma executives, all of you who are here today, are here because the way you have been doing business is unacceptable. Ten companies accounted for half of all the profits in the health-care sector last year. Nine of them were drug manufacturers. All but one of today's witnesses represent companies on this list. Drugmakers behave as if the patients and the taxpayers are unlocked ATMs full of cash to be extracted, and their shareholders are the customers whom they value above anybody else. So I am going to go through a short list of examples starting with AbbVie, which manufactures the top-selling prescription drug in America, the arthritis medication Humira. Over 6 years, the company doubled the price of a 12-month supply from $19,000 to $38,000. Can the patients opt for a less expensive alternative? They cannot, because AbbVie protects the exclusivity of Humira like Gollum with his ring--thick cobwebs of patents and legal tricks and shadowy deals with other drugmakers. All of them are in place to keep the cash flowing. Now I also want to address some very troubling information we just got from AbbVie's proxy statement. It is a document every publicly traded company has to file with the SEC. Page 37 shows that in 2017, a portion of CEO Richard Gonzalez's multi- million-dollar bonus was directly tied to sales of Humira. It appears the same incentive was in place in 2015 and 2016. In fact, the committee's review shows that all of AbbVie's top executives have the same arrangement. Mr. Gonzalez is welcome to respond, but the implication ought to be clear. From top down, AbbVie's leadership had reason to keep pushing prices and sales up. Now Pfizer, that company gets first prize for the emptiest pricing gesture in 2018. After stern Trump tweets, Pfizer said it would temporarily freeze the prices. But once the President got his flashy headlines, his gaze went elsewhere. Pfizer's former CEO told investors it was back to normal, another round of price hikes in 2019, including the pain medication Lyrica. Lyrica has increased 163 percent in price since 2012. Just one drug allowed Pfizer to pull in $4.5 billion in 2017. Merck gets second prize for emptiest pricing gesture of 2018. They made sweet-sounding promises after coming under criticism, but they cut prices for drugs that essentially produce no revenue for the company. Left untouched were the cash cows Keytruda and Januvia, which account for more than a quarter of the company's revenue. It is like promising car shoppers a great deal, except the only discounted model on the lot is an Edsel. Sanofi--this is a company wringing more and more cash out of people with an incurable disease. In 2010, a vial of this insulin cost less than $100. In 2018, it cost nearly $300. The company raised prices again in 2019. Considering the landmark breakthrough on insulin came early in the roaring 20s, nothing could justify this sudden price hike a century later. Diabetics who cannot afford the cost now self-ration and endanger their lives. But you know what? Investors are happy. AstraZeneca--a lesson in saying the quiet part out loud. In an interview earlier, the CEO complained that his $12-million salary made him the lowest-paid CEO in the whole industry, and he said it was annoying to some extent. His company, meanwhile, continues to raise the price of Symbicort, its $3-billion asthma drug. For some asthmatics, being able to breathe costs hundreds of dollars a month. And Johnson & Johnson gets the record today for flip- flopping. This January 7th at the JP Morgan Health Conference, the CEO said the pharmaceutical industry needs self-policing on prices. That sounded good, but 3 days later the company hiked the prices of hundreds of its drugs, including drugs that account for billions in Medicare spending. And finally, there is Bristol-Myers Squibb. In 2017, the company spent roughly $11 billion on dividends, stock buybacks, marketing, sales, and administrative costs that roughly triple the amount spent on R&D. Now I am going to close by saying that I want us to compare these concrete examples of two-faced scheming and profiteering with the central arguments that we are going to get this morning. The central argument from pharma is basically, the fault is always somebody else's. The health plans are at fault, the pharmaceutical benefit managers are at fault, regulators are at fault. What we know for certain is the history that pharma CEOs always say somebody else is at fault. We are also going to hear that the list price does not matter, that the true costs are just so complicated. But companies do not set and raise list prices for fun. Those prices are directly tied to the amount patients pay out-of- pocket at pharmacy windows from sea to shining sea. They are directly tied to what taxpayers spend on health-care programs. Then drugmakers point the finger at middlemen, the pharmacy benefit managers. I have said for years these pharmacy managers are wasteful and secretive, and take their cut without proving their worth to anybody. They are going to have their day before the committee too. But those pharmacy managers do not set list prices. The manufacturers do. And by the way, the manufacturers do not offer rebates for nearly 40 percent of Part D brand-name drugs. Those prices are going up. That is on the drug companies, not on the pharmacy managers. We are also going to hear that any changes in business as usual hurt research and development. A quick look at company finances shows that that is a fable. Revenue generated from American patients alone dwarfs what they spend on R&D worldwide. Drugmakers spend as much, if not more, on those exhilarating TV ads and office-to-office salesmen as they spend on research and development. And if lower prices would diminish R&D, why don't costly dividends? Why don't stock buybacks? Is the stock price more important than inventing that next miracle cure? Even if you buy the specious argument that a drug's list price at launch is driven by research costs, what could justify arbitrary price increases year after year, long after the research and development spending is done? Finally, we are going to hear about how patients can get coupons. But if this was so generous, why can't drug companies just lower prices across the board? I believe it is just more slick branding, branding that allows companies to keep the status quo cash cow rolling along. I will close with this. I was there when seven big tobacco CEOs testified in a committee room just like this one. They lied that day. This committee, the chairman and I, expect better than that this morning. Your profits are outsized compared to others in the industry. You get a massive portion of your revenue from American taxpayers, and you bear none of the consequences of these skyrocketing prices. It is long past time to drop the excuses and take concrete action to make medicine in America more affordable. Thank you, Mr. Chairman. [The prepared statement of Senator Wyden appears in the appendix.] The Chairman. Now I will introduce our seven witnesses, but once again, thank you for participating in this very important hearing on a very important topic. We are grateful for your participation and cooperation with our committee. The first witness is Richard Gonzalez, chairman and chief executive officer of AbbVie, Incorporated. Then we will hear from Pascal Soriot, DVM, executive director and chief executive officer of AstraZeneca. Then we will hear from Giovanni Caforio, M.D., chairman of the board and chief executive officer, Bristol-Myers Squibb; then Jennifer Taubert, executive vice president and worldwide chairman of pharmaceuticals for Johnson & Johnson; Kenneth C. Frazier, chairman and chief executive officer of Merck and Company; Albert Bourla, DVM, Ph.D., chief executive officer of Pfizer; and Dr. Olivier Brandicourt, M.D., chief executive officer of Sanofi. We welcome all of you, and we will start in that direction. And you have been given 5 minutes. I do not gavel you down at the end of 5 minutes, but I wish when the red light would come on, you would start to summarize, if you have not finished. So we will start with Mr. Gonzalez. STATEMENT OF RICHARD A. GONZALEZ, CHAIRMAN AND CHIEF EXECUTIVE OFFICER, ABBVIE INC., NORTH CHICAGO, IL Mr. Gonzalez. Thank you, Chairman Grassley, Ranking Member Wyden, and members of the committee. I am Richard Gonzalez, and I am the chief executive officer of AbbVie, a company dedicated to developing new innovative medicines for some of health care's most challenging diseases, such as cancer, Alzheimer's, viral infections, and autoimmune diseases. Since our inception in 2013, AbbVie has invested approximately $50 billion in pursuit of that goal. However, because we were tackling some of medicine's most challenging problems, solutions do not come easily, nor without significant risks. Where we have succeeded, we have been able to provide cures for fatal diseases like hepatitis C and significantly alter the disease progression for certain cancers, lessening the burden of illness on patients and on the health-care system. This is what the 30,000 employees of AbbVie are dedicated to doing. We agree that access to life-saving medicines is a critical issue, and we look forward to sharing our perspectives with you. There is no one solution to this complex issue, but AbbVie is committed to working with the committee and others on how we can better partner in your efforts to address pharmaceutical pricing and access. AbbVie and the rest of our industry must play a role in solving these issues and be prepared to work together with the insurance industry, the administration, and you to find a better path for American patients. My remarks today will focus on one aspect of this inquiry, the Medicare Part D benefit design, which, even after pharmaceutical list prices are lowered, still contributes to making innovative therapies cost-prohibitive for many Medicare patients. In general, the Medicare Part D program has worked well. Its market-based structure and utilization of formularies encourages competitive price discounts that have yielded significant savings to the government since the Part D benefit went into place back in 2006. However, despite these cost savings, Part D patient out-of-pocket costs have significantly increased. Some would blame that solely on high drug prices, and we agree that price should be part of the discussion. But it is also important to acknowledge that science has enabled us to advance the standard of care far beyond what was possible when the Part D benefit was originally designed. Many of today's specialty medicines offer significant advancements in treating or curing serious chronic or life- threatening conditions and save significant amounts of money for the health-care system by decreasing overall health-care costs. Yet these therapies are also costly. Due to the structure of the Part D benefit design, patients are charged out-of-pocket costs on a medicine's list price, which does not reflect the market-based rebates or discounts that Medicare receives. We are encouraged by the proposed rule that would reflect manufacturer's discounts in patient's Part D out-of-pocket payments. This is an important step in the right direction, but we believe more must still be done to help Part D patients. Let me give you a recent real-world example that demonstrates the challenge with the current Part D benefit design, and why the focus solely on list price does not fully address the access challenges. An uninsured hepatitis C infection leads to downstream medical costs for surgery, chemotherapy, and radiation for patients who progress to needing a liver transplant or having liver cancer. Today we can cure hepatitis C with drugs. This cure is highly cost-effective for the overall health-care system. In 2017, AbbVie launched Mavyret, a highly effective cure for HCV. At the time, the list prices for the competitive alternatives were as high as $94,500 for the most commonly prescribed treatment duration. We launched Mavyret at a list price that was 72 percent lower. But even though we cut the list price of an HCV cure--for most patients by 72 percent-- Medicare Part D patients' out-of-pocket obligations are still too high for many patients to access this medicine. We believe it is important that discussions about access and affordability include a focus on how to alleviate Medicare Part D out-of-pocket burdens above and beyond just lowering list price. We are prepared to step up and discuss how companies like ours can shoulder more of the burden of the patient out-of-pocket expense as we do in other areas. We believe AbbVie, the rest of the pharmaceutical industry, and the insurance providers should come together with the administration and you to work towards solutions that make life-changing medicines more affordable to Part D patients. I can assure you AbbVie is committed to doing its part, and we look forward to working with you. Thank you. [The prepared statement of Mr. Gonzalez appears in the appendix.] The Chairman. Mr. Soriot? STATEMENT OF PASCAL SORIOT, CHIEF EXECUTIVE OFFICER, ASTRAZENECA, WILMINGTON, DE Mr. Soriot. Chairman Grassley, Ranking Member Wyden, and members of the committee, good morning. I appreciate the invitation to address concerns regarding the pricing of medicines in the United States. My name is Pascal Soriot, and I am the CEO of AstraZeneca. Our company is dedicated to science and innovation. And in 2018, we invested nearly $6 billion in research and development, 28 percent of our product sales, which is well above the industry average. In the past 2 years, our commitment to R&D has resulted in 18 significant FDA approvals and 5 breakthrough designations. However, I know that these statistics are meaningless unless patients can actually afford our medicines and those medicines reduce overall health-care costs. I am here to discuss how we can work with other stakeholders to take specific actions that address pricing concerns. My first proposal is that we move away from the current rebate system while continuing to work with payers and PBMs to ensure robust negotiations. The current system is built on high list prices coupled with rebates. This is not sustainable, and all of us have a role to play. For example, the estimates for 2018 show that across our medicines, our average rebate is nearly 50 percent of our gross revenues in the U.S. Despite this, in recent years in our primary care portfolio, we have seen flat to declining net effective prices for most of our medicines. As a company dependent upon government action for eliminating rebates in commercial and in Part D, we are prepared to reduce our list prices by an equivalent amount of rebates, less the appropriate market-based fees, to those in the supply chain. This will actually reduce overall costs not only for patients, but also for the government. My second proposal is that if a change of the current system is not possible, a portion of discounts and rebates could be used to create out-of-pocket caps for Medicare patients. This approach is used successfully in some other countries. Actually, it gives patients greater certainty in their out-of-pocket cost. Third, I believe that value-based agreements have the potential to transform how medicines are priced and reimbursed in the U.S. In our own value-based agreements, the price of a medicine is directly linked to the value it provides to patients, to payers, and to the health-care system. For example, last month we announced an agreement for University of Pittsburgh Medical Center Medicare patients who are prescribed Brilinta. This innovative contract directly reduces the cost for patients, and it ties price to clinical value, basing our payments on patient outcome. These types of agreements can be especially effective for medicines where there is limited competition. As an example, for one of our oral oncology medicines we agreed to reimburse a large payer for discontinued use because patients did not respond to treatment. And we have reimbursed the payer under those agreements 20 percent of the time. To that end, I appreciate the support of Senator Warner and Senator Cassidy for value-based agreements, as demonstrated by their request for input on the Patient Affordability, Value, and Efficiency, the PAVE Act. My fourth proposal is that we must encourage biosimilars and eliminate policy and commercial barriers to their greater use. Biologics are actually making very important contributions to medicine, and I believe a vigorous biosimilar market would reduce costs like generics do for small molecules. In fact, biosimilars have gained up to 85 percent market share in the 5 largest countries in Europe, and the average biosimilar discount is between 40 and 80 percent. In closing, I would like to emphasize my strong commitment to addressing the concerns raised by the committee. I believe that we can work together to find solutions that continue to allow manufacturers to innovate, while creating a more efficient and more affordable system. There are no easy answers, it is very clear, but we want to be a constructive partner. Thank you, and I look forward to the discussion. [The prepared statement of Mr. Soriot appears in the appendix.] The Chairman. Dr. Caforio? STATEMENT OF GIOVANNI CAFORIO, M.D., CHAIRMAN OF THE BOARD AND CHIEF EXECUTIVE OFFICER, BRISTOL-MEYERS SQUIBB COMPANY, NEW YORK, NY Dr. Caforio. Chairman Grassley, Ranking Member Wyden, and members of the committee, good morning, and thank you for the opportunity to be here today on behalf of the 24,000 employees of Bristol-Myers Squibb. I look forward to working together to align incentives to ensure all Americans have access to the medicines they need. I am a physician. I joined the pharmaceutical industry 30 years ago because of the impact companies like ours have on patients. We should all be proud that American companies lead our industry. Our researchers have contributed to the development of medicines that have reduced mortality from cardiovascular disease, helped transform HIV/AIDS into a chronic disease, and are now making significant progress with the treatment of cancer. Just 10 years ago, the idea of harnessing the immune system to treat cancer was viewed with great skepticism. But our researchers saw the promise of that approach and ignited an era of scientific innovation that has changed survival expectations in multiple tumors. Prior to the availability of immuno- oncology treatments, only 25 percent of patients diagnosed with metastatic melanoma were alive after 1 year. Today, thanks to immuno-oncology therapies, that number has increased to 74 percent. The potential of this approach has also been seen in lung cancer, kidney cancer, and many other difficult-to-treat tumors. These patients now have a chance for quality and long- term survival. But not all patients respond to current immunotherapies. And so we must do more. We recently opened a new facility dedicated to investigating what we call immuno-oncology resistance. And we continuously seek external innovation to augment our pipeline. In fact, in this context, we recently announced our plans to acquire Celgene. Our goal is to bring together the drive and dedication of two science-driven companies to do even more for patients. As a physician, I do recognize that medicines are only helpful if patients and health-care systems can afford them. We share the committee's concern with escalating health-care costs and believe that our responsibility extends to ensuring that patients have access to and can afford our medicines. For this reason, the average net pricing across our U.S. portfolio of medicines increased by 5 percent or less year-over-year for the last 5 years. Importantly, it did not increase at all in 2018. And we expect that it will not increase in 2019. Despite this fact, we do recognize that patients' out-of- pocket costs continue to increase. We believe it is possible to work together to realign incentives to ensure patients can afford medicines without stifling scientific innovation. So what are the solutions? We are supportive of the proposed rule aimed at reforming the rebate system with a focus on what is best for patients. We need to ensure more generics are available whenever permissible under our system. We support value-based purchasing arrangements that tie payments to value. These models can reduce costs, improve access and patient adherence, and contribute to better outcomes. We applaud efforts by Health and Human Services and this committee in all of these areas. We do believe the U.S. should not adopt policies that stifle innovation in other countries. Outside of the U.S., reimbursement of new medicines often takes more than 2 years. For example, nearly 4 years ago our Opdivo and Yervoy regimen was first approved to treat metastatic melanoma in the U.S. Today, 6 of the 16 countries included in the international price index proposal still do not provide reimbursement for this combination, which is the standard of care for the treatment of this cancer. This is why we do not support the proposed international price index model for Medicare Part B drugs. I would like to leave you with a few thoughts. First, we recognize the need for change. We are witnessing a historic era in biomedical innovation. American research-based companies are leading the way to help patients whose diseases cannot be adequately treated with today's medicines. But we must ensure that patients have affordable access to new innovations. And we should work on policies that support and reward access and these investments. I look forward to working together to implement real change that broadens access to innovative medicines for patients. In closing, on behalf of my colleagues at Bristol-Myers Squibb and the patients we serve, my sincere thanks for your time and attention today. The Chairman. Thank you very much. [The prepared statement of Dr. Caforio appears in the appendix.] The Chairman. Now, Ms. Taubert? STATEMENT OF JENNIFER TAUBERT, EXECUTIVE VICE PRESIDENT, WORLDWIDE CHAIRMAN, JANSSEN PHARMACEUTICALS, JOHNSON & JOHNSON, NEW BRUNSWICK, NJ Ms. Taubert. Chairman Grassley, Ranking Member Wyden, members of the committee, thank you for the opportunity to be here today. I am Jennifer Taubert, and I lead the Janssen Pharmaceutical Companies of Johnson & Johnson. We focus on discovering and developing transformational medicines for some of the world's most challenging diseases, including multiple myeloma, prostate cancer, HIV, schizophrenia, and Crohn's disease, among others. Like many of you, I know what it is like when a loved one faces serious illness. My own mother died of lung cancer while in her 40s, and at that time there was very little that could be done for her. I have committed my career to bringing families hope: hope for years of life, for the chance to be there for a daughter's wedding or for a grandson's birth. Janssen invested $8.4 billion in research and development last year in the search for medical breakthroughs, making us one of the world's top R&D investors in any industry. In fact, our investment in R&D last year was 86 percent more than we spent on sales and marketing. And this substantial investment is changing lives. It has helped turn HIV from a death sentence to a manageable disease. Our targeted cancer medicines have helped patients with some of the most deadly cancers live longer, in some cases for many years. Medicines not only help patients and families. They also help lower overall health-care costs by keeping people well, preventing the need for expensive procedures and hospitalizations. But medicines cannot make a difference if the patients who need them cannot afford them. We understand the concerns about the cost of health care. Our approach recognizes our responsibility to patients today and patients tomorrow. Patients today need access to our medicines. Patients tomorrow count on us to deliver cures and treatments for the most challenging diseases. When we price our medicines, we balance the value to patients, the importance of affordable access, and the importance of developing future breakthroughs. The list price is a starting point that is reduced by required discounts to government programs and rebates to payers so they will grant patients access to our medicines. Last year our discounts and rebates amounted to $21 billion and our net price decreased 6.8 percent. Unfortunately, while our overall price decreased for the past 2 years, patients have seen their out-of-pocket costs go up. One reason is increased enrollment in health plans that require patients to pay more for their prescriptions. As one recent analysis shows, patients are required to pay 13 percent of overall pharmaceutical costs, versus only 3 percent of hospital costs, even though medicine can help keep patients out of the hospital. Above all, we need an American solution to this American challenge. We must ensure that today's medicines are affordable, while at the same time preserving the innovation that has delivered so much and promises even more. We must maintain the hallmarks that make American health care remarkable: access to innovative therapies, personal choice, and doctors and patients making decisions based on what is right for each individual. At Janssen, we are committed to being a part of the solution. We believe open dialogue is essential. That is why in 2016, we began issuing the Janssen Transparency Report, sharing information about how we invest our resources, price our medicines, and help people access them. And we recently announced our plan to include list price and potential patient out-of-pocket costs in our direct-to-consumer TV advertising. In the same spirit of open dialogue, we have consistently brought forward ideas and perspectives to both Congress and the administration to fix what is not working while preserving what is. We have included more details in our submitted testimony, but I want to touch on a few points today. First, while Medicare Part D is working for many seniors and has been effective in containing costs, we believe an out-of-pocket cap is a needed protection. Second, in Medicare Part B, we have proposed options that would allow Medicare to continue to achieve negotiated savings through market competition while reducing costs. And third, we support rebate reforms that ensure patients benefit from the negotiated rebates and discounts--$150 billion in total in 2017 alone--and as a result, have patients see lower out-of-pocket costs at the pharmacy. We are on the verge of extraordinary progress that could change our lives and the lives of our children and grandchildren. At Janssen, we are committed to bringing that promise to life. Thank you very much. The Chairman. Thank you. [The prepared statement of Ms. Taubert appears in the appendix.] The Chairman. Mr. Frazier? STATEMENT OF KENNETH C. FRAZIER, CHAIRMAN AND CHIEF EXECUTIVE OFFICER, MERCK AND COMPANY, INC., KENILWORTH, NJ Mr. Frazier. Mr. Chairman, Ranking Member Wyden, and members of the committee, thank you for the opportunity to appear here today. Merck's mission is to save and improve lives around the world by bringing forward breakthrough medicines and vaccines. Research is at the core of Merck. Last year we invested $10 billion in R&D, 23 percent of product sales. And we have invested nearly $70 billion over the past decade. Over the last 5 years, we have also made capital investments of over $5 billion in the United States, and we plan to invest more than $9 billion more over the next few years to increase manufacturing capacity and to open two new research centers in the United States. We go where the science leads us, which means we do not focus only on diseases in wealthier countries. For example, we are proud to have deployed 70,000 doses of our experimental Ebola vaccine in the Congo, working in partnership with the United States government. The goal is to save lives even where no viable commercial opportunity exists. We do all this to serve patients. We fully understand that U.S. patients are having a harder and harder time affording the medicines they need. While medicine costs are growing at the slowest rate in years, our patients are too often being asked to pay more out of pocket. I am here to suggest some ways that together we can address this problem. First, we want to be clear that our industry has a duty to be responsible in our pricing practices and to contribute to solutions that address patient affordability. Merck has a history of responsible pricing. We publish information about our prices, and the rebates and discounts we provide to payers. Last year we pledged that we will not increase our average net prices across our portfolio by more than the rate of inflation annually Second, we must ensure that patients get the benefit of these large rebates and discounts. The incentives in the current system are badly misaligned with the growing gap between list and net prices, creating incentives to favor products with higher list prices. This misalignment hurts patients because their cost sharing is often based on the list price of a drug. We urge you to support action to ensure that patients benefit from these discounts. Third, we can significantly reduce drug spending for patients in the health-care system by ensuring that we have a viable biosimilars market in the United States. We urge Congress to encourage and support greater biosimilar utilization. Fourth, we believe that prices can better align with a drug's value, when manufacturers and payers are able to negotiate innovative contracts that base payment on a drug's benefit. We need to move to this type of system, but there remain major regulatory and operational obstacles to such value-based arrangements, which we urge Congress to address. We agree that manufacturers should be rewarded based on the value that our therapies deliver. Fifth, we support efforts to encourage generic competition. A version of Chairman Grassley's CREATES Act and similar policies could make needed reforms to encourage generic competition and ensure there is no inappropriate gaming of the system. We also support eliminating coupons in cases where brand name generic competition exists. Finally, we would like to work with the committee to find ways to end price gouging by some who excessively increase off- patent drug prices where there is no competition. These high prices hurt patients, and they do not create incentives for research. These changes could bring real relief to today's patients while preserving the incentives to invest in tomorrow's breakthroughs. Decades of research investment are now yielding life-changing discoveries. If we damage the biomedical ecosystem that thrives on these investments, we will surely limit what can be achieved for patients and society. The single most important thing we do at Merck is to persist in making large and risky investments in R&D that allow our thousands of researchers to sit at their lab benches to try to create something transformative despite the overwhelming odds that their efforts will not succeed, since more than 9 out of 10 compounds fail. I would like to end on a brief personal note. My mother died when I was a child, and my siblings and I were raised by my father. He was a giant in my life, and I was devastated when Alzheimer's took him away from us. Last year, after spending many years and over $1 billion, Merck had to end development of a promising Alzheimer's therapy because it did not work. Yet we continue on, seeking better approaches, and I truly believe that Merck or one of the other companies at this table will find a medicine that will avoid the pain of seeing a loved one taken away from them in this way. This vital work depends on having a U.S. market that is free, competitive, and predictable. We must work together to solve the affordability challenges of today's patients without jeopardizing the hopes of those waiting for tomorrow's cures. The changes I have discussed today have the potential to vastly improve the market while lessening the financial hardships many people face. I am here to pledge Merck's cooperation with you in creating such changes. Thank you very much. The Chairman. Thank you, Mr. Frazier. [The prepared statement of Mr. Frazier appears in the appendix.] The Chairman. Now, Dr. Bourla? STATEMENT OF ALBERT BOURLA, DVM, Ph.D., CHIEF EXECUTIVE OFFICER, PFIZER, NEW YORK, NY Dr. Bourla. Good morning. Chairman Grassley, Ranking Member Wyden, and members of the committee, thank you for the invitation. My name is Albert Bourla. I have been with Pfizer 26 years and just last month became its chief executive officer. I have to say that today I am particularly humbled to take part in such an important policy discussion within the United States Senate. When I immigrated into the United States 18 years ago, I could never have imagined such an honor. In that frightening moment when you hear that you or a loved one has been diagnosed with a serious disease, one question comes to mind: is there a treatment available? The answer to this question will change your life. Happily the answer, increasingly, is ``yes.'' New breakthroughs are coming quickly to treat many difficult and devastating diseases. But these breakthroughs will not do anyone any good if patients cannot afford them. And unfortunately, the horribly misaligned incentives within our health-care system often make medicines unaffordable for American patients. We need to fix this. Today, we would like to propose four ideas to drive meaningful savings for patients. The first idea is passing all rebates to patients. Pfizer supports a system in which transparent up-front discounts directly benefit patients, rather than the system where rebates are swallowed up by the supply chain. In the current system, for example, none of the approximately $12 billion that Pfizer paid in rebates, in 2018, found its way to American patients. If the proposed rule to share rebates with consumers at the point of sale is finalized, we estimate that seniors taking Pfizer medicines could save hundreds of dollars a year, on average. The second idea is less volume, less pay. Imagine a system where Pfizer gets paid based on the number of heart attacks we prevent, rather than on the number of pills we sell. In such a system, if our medicines do not produce good results, we should be paid less. And if they do, we should be paid more. Such value-based payment arrangements, if done correctly, can align the interests of patients, insurance companies, and biopharmaceutical companies around one shared goal, ensuring positive health outcomes for patients. I understand that several members of this committee are working on legislation to pave the way for these types of arrangements. And we applaud this effort. The third idea is around capping seniors' out-of-pocket medicine costs. Patients are increasingly being required to take on a disproportionately higher share of their medicines' costs. Today patients pay on average 14 percent of the cost of their medicines, but they pay only 3 percent of the cost associated with hospital stays, for example. This is forcing patients to forego taking needed medications or to limit their doses. This is bad, not only for patients, but also for overall system costs. Patients who do not take their medicines often end up in the hospital, costing much more to the system. An important first step is capping out-of-pocket costs seniors experience in the medical drug program. And the fourth idea is to knock down barriers to lower-cost biosimilars. Others have spoken about it. Adverse incentives that favor higher-cost biologics are keeping biosimilars from reaching patients. In many cases, insurance companies declined to include lower-cost biosimilars in their formularies because they would risk losing the rebates from covering higher-cost medicines. I cannot think of a more concerning example of a broken system, and we need to do something about it. In closing, Pfizer is all about breakthroughs that change patients' lives. This is why our more than 90,000 colleagues, many of whom work in laboratories and manufacturing plants in States represented by members of this committee, come to work every day. And it is why we are here today, to work with you and all stakeholders to find ways to ensure that we can continue to discover medicines that can change patients' lives. The Chairman. Thank you. [The prepared statement of Dr. Bourla appears in the appendix.] The Chairman. Now to Dr. Brandicourt. STATEMENT OF OLIVIER BRANDICOURT, M.D., CHIEF EXECUTIVE OFFICER, SANOFI, BRIDGEWATER, NJ Dr. Brandicourt. Chairman Grassley, Ranking Member Wyden, and members of the committee, thank you for the opportunity to appear before the Senate Committee on Finance to discuss pharmaceutical pricing, affordability, and patient access. I am Olivier Brandicourt, the chief executive officer of Sanofi. I understand the anger about rising out-of-pocket costs for many medicines, including insulins. I appreciate the confusion as to why patient costs continue to rise, even when the amount that PBMs and health plans pay declines. This situation is unacceptable and unsustainable for too many patients. My goal today is to have an honest discussion about how the system works, and how it can be improved. As you may know, 2 years ago Sanofi announced our progressive and industry-leading principles. First, we made a pledge to keep price increases at or below the U.S. national health expenditure projected growth rates. Second, we committed to providing a clear rationale for pricing when we launch new medicines. And third, we have increased transparency by providing each year information about our list and net prices across all of our medicines. In 2018, the average aggregate least-price increase across all Sanofi medicines in the U.S. was 4.6 percent, while the average aggregate net price--that is the price actually paid to Sanofi--declined by 8 percent. So declining average aggregate net price in 2018 represents a third consecutive year in which the amount paid by payers across all of our medicines went down. I feel a special obligation to address the pressing issues around access and affordability of our insulins. Insulin is a clear example of the growing gap between list and net prices. Since 2012, the net price of Sanofi insulins has declined 25 percent. Yet patient out-of-pocket costs have continued to rise. If you take Lantus, for instance, our most prescribed insulin, the net price has fallen by 30 percent since 2012. Yet over the same period, average out-of-pocket costs have risen approximately 60 percent for patients with commercial insurance and Medicare. It is my belief that declining net prices should result in lower out-of-pocket costs for patients. But clearly, this is not always the case. Addressing these prices alone will not be sufficient to solve the problem of patients' out-of-pocket costs. As we look for solutions, we must have protections for patients and link responsible pricing to both access and affordability. Every actor in the system has a role to play, and Sanofi takes this call to action seriously. There are different ways to accomplish these goals, and Sanofi could support options that align to our core principles. First, changes to the drug pricing and reimbursement system must be holistic, factoring in all actors in the system. And the majority of benefits should accrue to patients. And second, to maintain a strong environment for innovation in the United States, the government should not directly control the price of medicines, either through Federal Government price controls, or worse, outsourcing price decisions to other countries. To ensure that responsible pricing translates to better access and affordability for patients, Sanofi supports the policy solutions outlined in my written testimony, including several policies introduced by members of this committee, such as the CREATES Act, the C-THRU Act, and the SPIKE Act. So thank you for the invitation to speak with you today, and I look forward to answering your questions. The Chairman. I thank all of you for your testimony. [The prepared statement of Dr. Brandicourt appears in the appendix.] The Chairman. And I think I heard from each of you that you are willing to work with us and people in the administration to find solutions to these problems. I welcome that sort of cooperation and just implore you that that cooperation will have to go on weeks beyond this hearing, because we would not expect to get all the information we need just at this hearing. Now, we will go to questioning. Do not start my clock yet. I have not asked my questions yet. [Laughter.] Before I ask questions, if I could have--obviously, we have a very important meeting here. We have seven witnesses. We have 24 or 25 members of this committee. I think I am fairly liberal in letting people ask questions. But I want to repeat something I have said before, and that is that if you will take your 5 minutes, and if there are a few seconds left, you ask a question then--hopefully, it is a short question at that point, and hopefully there is a short answer at that point. What irritates me about that process is when somebody thinks they can have back and forth for 3 or 4 minutes after you ask your last question. So I am asking you, if you would please be tolerant towards people who abide by the 5 minutes, to be respectful of that so that everybody gets a chance to ask questions. Now my 5 minutes starts. [Laughter.] I want to thank those of you who are here who said you would be supportive of legislation that I have been backing for a long period of time: CREATES, which is sponsored by Senator Leahy and this Senator, and Pay-for-Delay by Senator Klobuchar and this Senator. So those are bipartisan bills. One other bipartisan bill that you probably do not know about yet--it was introduced by Senator Wyden and me a couple weeks ago--is called the Right Rebate Act, which would close a loophole that was exploited by Mylan in the EpiPen case. So leading to my questions, starting off, Ranking Member Wyden and I have been working--before I became chairman of this committee again, we investigated a lot about Gilead's pricing decisions for hepatitis C drugs. During that investigation, we acquired a document that listed some factors that Gilead considered when it priced those drugs. Those factors included the risk of ``public outcry'' or ``the likelihood of a letter from Congress'' or the ``likelihood of a congressional hearing.'' So taking off from that point, here is a very simple question to answer, I think. So I want a ``yes'' or ``no'' from each of you. When your company prices its drugs, do you consider the risk of negative public opinion in the pricing of that drug? We will start with AbbVie. Mr. Gonzalez. Senator---- The Chairman. Can you answer ``yes'' or ``no''? Mr. Gonzalez. Yes, we do. The Chairman. Yes, you do. Okay. What about AstraZeneca? Mr. Soriot. Yes, we do, Senator. Amongst other factors, of course, but we do. The Chairman. Okay. What about Bristol-Myers? Dr. Caforio. Yes, we do, Senator, among many factors. The Chairman. Okay. Johnson & Johnson? Ms. Taubert. Yes, we do, Senator, as well as affordable access to the medicines for the patients. The Chairman. Okay. What about Merck? Mr. Frazier. Yes, we do, among other factors. The Chairman. Okay. And what about Pfizer? Dr. Bourla. Yes, we do, among other factors. The Chairman. And what about Sanofi? Dr. Brandicourt. Yes, we do, among other factors. The Chairman. Okay. Thank you. Another ``yes'' or ``no'' question: when determining list price, do you consider the likelihood of a congressional inquiry? Let's start with AbbVie. Mr. Gonzalez. No, we do not. The Chairman. What about AstraZeneca? Mr. Soriot. No, we do not, Senator. The Chairman. What about Bristol-Myers? Dr. Caforio. No, Senator, we do not. The Chairman. And what about Johnson & Johnson? Ms. Taubert. No, Senator, we do not. The Chairman. Okay; and Merck? Mr. Frazier. Not explicitly. I would say we do care what the public thinks. The Chairman. Okay. And what about Pfizer? Dr. Bourla. No, we do not think---- The Chairman. Okay. What about Sanofi? Dr. Brandicourt. Same, Senator; we do not. The Chairman. Okay. Then I would have another ``yes'' or ``no'' question. When your company prices its drugs, do you take into account the fact that a key player is the Federal Government? Let us start with AbbVie. Mr. Gonzalez. We evaluate all the channels when we make determinations on price and affordability. The Chairman. Okay. So that obviously would include the Federal Government. Mr. Gonzalez. Correct. The Chairman. AstraZeneca? Mr. Soriot. Yes, we use the same approach, and of course the Federal Government is a very key aspect of our deliberations. The Chairman. Okay. Bristol-Myers? Dr. Caforio. Yes, Senator, because the Federal Government is a large part of our---- The Chairman. Okay. Johnson & Johnson? Ms. Taubert. Yes, we take into account the value to patients, the health-care system, and society, and the government is a key part of that. The Chairman. Okay. And Merck? Mr. Frazier. Yes. The Chairman. Okay. And Pfizer? Dr. Bourla. Absolutely. The Chairman. And then Sanofi? Dr. Brandicourt. Yes. The Chairman. Okay. My last question. ``Yes'' or ``no'': some of you have voiced support for the recent rebate rule proposed by the administration. Should the administration finalize this rule, will you commit to lowering your drug prices? Mr. Gonzalez. Mr. Chairman, we are supportive of the rule. We would like to see it in its final form, obviously, to make a final decision. But we are supportive of taking the discount to the patient at the point of sale. The Chairman. Okay. AstraZeneca? Mr. Soriot. The same for us, Senator. I would go one step further: if the rebates were removed from the commercial sector as well, we would definitely reduce our list prices. The Chairman. Okay. And Bristol-Myers? Dr. Caforio. We have the same position, sir. The Chairman. Okay. And Johnson & Johnson? Ms. Taubert. Yes, we are supportive, and that definitely would be my goal. We would just need to see the final legislation, provided that there are not additional fees that are added into the system to compensate for the rebates. The Chairman. Okay. Merck? Mr. Frazier. I would expect that our prices would go down if we change the system, again, on the commercial side as well as the Medicare side. The Chairman. Okay. Pfizer? Dr. Bourla. It is our very clear intention that we will not keep a single dollar from these rebates. We will try to move every single penny to the patients. And we think if this goes also to the commercial plans, that would be even better for more patients. The Chairman. Okay. Sanofi? Dr. Brandicourt. Lowering list price has to be linked to better access and affordability at the counter for the patients. The Chairman. Okay. I want fellow colleagues to know that I stopped at 5 minutes and 26 seconds. Senator Wyden? Senator Wyden. Thank you, Mr. Chairman. Let me start, if I could, with you, Mr. Bourla, on this list price question. And I want to see if we can do a couple of ``yes'' or ``no'' questions. Is it correct that your company, and nobody else, sets the starting price for all drugs sold by Pfizer? That is a ``yes'' or ``no.'' Dr. Bourla. It is a negotiation with PBMs, and they are very powerful. Senator Wyden. But you still get to set the list price? Dr. Bourla. Yes, but we set---- Senator Wyden. Okay. Dr. Bourla [continuing]. The list price and the rebates based on---- Senator Wyden. Is it correct when a hypothetical patient-- let us call her Mrs. Jones--goes to pay for her drug at the pharmacy counter, her coinsurance is based on the price of the drug you set? Dr. Bourla. It is correct in many cases. Senator Wyden. Okay. I just want you all to know that the number one reason consumers are getting hammered is because these list prices-- and you have the last word with respect to where they are--are unaffordable. And the high prices are tied to what the consumer pays at the pharmacy counter. And all this other stuff you talk about--the rebates and the discounts and the coupons--all this other stuff is window dressing, all of it. And the fact is on Part D, 40 percent of the drugs do not even have a rebate. So I want it understood--particularly, because I have asked you, Dr. Bourla--I think you and others in the industry are stonewalling on the key issue, which is actually lowering list prices. And reducing those list prices is the easiest way for American consumers to pay less at the pharmacy counter. Now, Mr. Gonzalez, I want to ask you some questions relating to the international pricing situation. Drug prices are much higher in the United States than in other developed countries, on average 40 percent higher. In 2017, AbbVie made $9.9 billion in revenue outside the United States. So my first question to you is, do you make a profit on the drugs that you sell in Germany or in France? Mr. Gonzalez. Yes, we do. Senator Wyden. So if you do, and you have said that that is the case, if you can turn a profit in a country with dramatically lower prices, you can do the same thing in the United States. How is that not gouging the American consumer with high prices, even though you are giving other people in Western industrialized countries a better deal? Mr. Gonzalez. Senator, it is a great question. And the reality is--and I do not think it is just unique to AbbVie-- that prices vary dramatically around the world. There is no question, at least in AbbVie's business for the most part, the U.S. has some of the highest prices in the world. That is not universally true. The government has some relatively low prices in comparison. But I think the fundamental issue is this: our system is built around a variety of pricing around the world, but that overall system supports our R&D model. If a market the size of the United States were to collapse to the lower end of that pricing model, then I can just tell you AbbVie would not be able to invest the level of R&D that it invests today. So that is the reality. Senator Wyden. Well, I think time is short. As I noted in my opening statement, global R&D spending is far less than the revenue you make in America. American patients bring in more than enough revenue to cover your R&D costs. I mean, I am going to have town meetings in a few days at home, and people will say, ``Ron, this is ridiculous that we are getting gouged when people around the world are getting a better deal.'' And what you have told me today is: (a) they are getting a better deal and you can make a profit; and (b) it is somehow tied to research and development. And the fact is that research and development is less than the revenue that you are making in this country, and that is why people are so angry. And I would also like to note that a Humira biosimilar was launched in Europe last year, and due to AbbVie's anti- competitive behavior in the United States, that same biosimilar will not be available here until 2023. You have a double standard. You are willing to sit by and hose the American consumer and give the breaks to people overseas. So I am going to wrap up and stick to the chairman's time limit by asking you for a response in writing. So that we can better understand the situation for the drugs you sell in other countries, I would like to know, for the drugs you sell in other Western industrialized countries--just the Western industrialized countries--does your company make or lose money? Can you get that to me in writing within 10 days? Mr. Gonzalez. I can give it to you right now. Senator Wyden. Okay. Mr. Gonzalez. We make money in any country that we sell in unless we choose to donate the product into those countries. And we do that in certain countries that cannot afford it, but not the Western---- Senator Wyden. I would like it in writing. Mr. Gonzalez. Okay. One thing I would like to point out that I do not think is totally accurate that you described, at least for AbbVie, is we spend $5.2 billion dollars in R&D. We make $5.6 billion dollars in earnings. So our R&D is almost equivalent to what our earnings are. Senator Wyden. Well---- The Chairman. I am going to---- Senator Wyden. We will continue that. The Chairman. I am going to list four names at a time. Roberts will be next, and then Stabenow, and then Enzi, and then Cantwell. So if you are irritated about how you might be on this list, take it out with one of your colleagues on the committee, because I am reading it just the way the staff gave it to me. So, Senator Roberts? Senator Roberts. Thank you, Mr. Chairman. I will try to be timely. This whole situation reminds me of when Mark Twain, i.e., Samuel Clemens, went to Missouri--that was his first mistake-- and made some remarks to a small town. The mayor afterwards said, ``Well now, we have the tar and the feathers and a rail. We would like to ride you out of town on a rail.'' He said, ``If it was not for the honor of it, I'd just as soon not do that.'' And I think in some ways that is where you are sitting right now. I worry about the cost. I worry about the access. I worry about the value. I worry about the fact that when I go--I did just last night, and all of a sudden I found out that the prescription I had cost twice as much. I still have not quite figured that out. I do not know which one of you to blame. But at any rate, I worry about HHS. I worry about CMS. I worry about the Federal Government taking over with regards to the decisions that you make. I also worry about what the distinguished Senator from Oregon described as a terrified public, and certainly we do not want any liars. I want to ask you one simple question. Staff has arranged about seven good questions. I will submit them for the record. Under the banner of certainty and predictability, what keeps you up at night? In other words, if in fact we invited you back and you could come back--well, let me put it another way. What would happen if you ran into some things that were unprecedented and you would not be here? We would not have the Magnificent Seven, if in fact that's why we won a ``W.'' What I want to know is, what is the thing that keeps you up at night, so you could be a viable company now and down the road to achieve what we all want in terms of access and cost? And I am going to start with Dr. Brandicourt, because I want to go from right to left for a change. Dr. Brandicourt. Thank you, Senator. What keeps me up at night is ensuring that I have a pipeline of new products which is innovative enough to alleviate, you know, some of the disease burdens in the countries where we are. So it is making our company meaningful and delivering what we are supposed to do best. Senator Roberts. Thank you. Dr. Bourla. Mr. Senator, the reason we exist is to bring breakthroughs that change patients' lives. And this is what keeps me up, and this is the reason why our employees come to work. This is the reason why our investors invest in us. If our pipeline will not deliver on the promise--and this is very challenging, because you are dealing with very difficult diseases to crack--then we will not be able to fulfill our promise to society and will not be able to fulfill our promise to investors. Senator Roberts. Mr. Frazier, thank you for your five-point plan. What say you? Mr. Frazier. I would say, Senator, the thing that keeps me most up at night is the concern that we will not have a viable, predictable market that will allow people to continue to put the very large amounts of money at risk for a long period of time in an attempt to find solutions to some of the hardest problems, like Alzheimer's, that have evaded solutions. And what really concerns me is when we do not treat these issues as systemic issues and the public thinks that they have to have outrageous solutions to the problem where, in the future, we will not get these drugs. So I would hope that we could talk about these things systemically and try to come up with the kinds of solutions that will, in fact, make patients have access to medicines today while allowing tomorrow's breakthroughs to happen. Thank you. Senator Roberts. Thank you. Ms. Taubert? Ms. Taubert. Senator, the easy diseases have largely been solved. It gets harder and harder as we go after new treatments and new cures for ever more challenging diseases. So from our perspective, what keeps me up at night is that investment in innovation and the ability to continue to invest to be able to go after the cures and the diseases that we really want to solve. Senator Roberts. Thank you. Dr. Caforio? Dr. Caforio. Mr. Senator, I am a physician, as I said earlier. What keeps me up at night is our patients who still do not have an opportunity for their cancer to be treated. And as a result of that, I am really focused on, first, continuing to invest in R&D together with the 7,000 scientists at Bristol- Myers Squibb, and also making sure that every patient who needs one of our medicines has access to it. Senator Roberts. Mr. Soriot? Mr. Soriot. Senator, two things, actually. One is making sure we have the best science, the best scientists, and an environment that stimulates their innovation. The second is really to come up with ways to demonstrate the value of our products. I believe that medicines are actually part of the solution, not part of the problem. And it is sad that we are talking about those difficulties patients are facing. In the last 15 years, the mortality for cardiovascular disease has declined by 35 percent. Most of this is due to good treatments for hypertension, cholesterol. And in fact, it is cost-effective. We keep patients out of the hospital. So the one thing that really keeps me up at night is, how do we demonstrate the value we bring, and how do we reduce overall health-care costs? Senator Roberts. Mr. Gonzalez, I am out of time. The Chairman. No, he can answer. You asked your question. Go ahead. Senator Roberts. Thank you for being so liberal. [Laughter.] Mr. Gonzalez. Thank you, Senator. There are two things that keep me up at night. The first is we, like many around this table, are working on some of the toughest diseases that are out there, which takes on tremendous amount of risk--I am sure you heard that many, many times. But the reality is, when we work on these diseases, like Alzheimer's as an example, when someone comes up with a beneficial treatment for Alzheimer's, it is going to change the lives of patients, families, and it is going to reduce dramatically health-care costs. But not necessarily the cost of medicine. The cost of medicine is going to go up. The cost of nursing homes is going to go down. And systems have a very difficult time trying to measure that benefit, but the reality is, when you are working in these areas with these kind of intractable diseases, that is the ultimate payback that the system has to be able to evaluate. Senator Roberts. Thank you. The Chairman. Senator Stabenow? Senator Stabenow. Thank you very much, Mr. Chairman and Ranking Member. Thank you for being here. I will tell you what keeps people in Michigan up late at night. It is the cost of life-saving medicine for themselves, their children, their parents. And so that is why it is important that we are here, and I am glad we are talking about research, because I would like to step back a moment and talk about who basically is funding research, and I hope you will say ``thank you'' to the American taxpayer, because American families fund the National Institutes of Health. A recent report found that NIH-funded research contributed to every single one of the 210 new drugs approved by the FDA from 2010 to 2016, and that American taxpayers contributed more than $200 billion in grants--$200 billion in grants to your companies and others. Grants, not loans; grants to develop these drugs. That is about 200,000 years of accumulated research. And I support that, because the basic research is something that I believe we all need to share in. At the same time, when you then go from there and are doing R&D, you can write that off your taxes, so American taxpayers subsidize you again. Now, according to the most recent SEC filings, the seven companies--all of you here today--have spent about $80 billion on selling, marketing, and administrative expenses last year, which was $22 billion more than you spent on R&D. So let us just be clear on this: American taxpayers, we are happy to help you be able to develop these drugs, but I can tell you, people in Michigan just feel that the bargain ought to be that they ought to be able to afford the medicine after they have helped to develop it. Between 2006 and 2015, the largest 25 drug companies enjoyed an average annual profit of between 15 and 20 percent. Most other large Fortune 500 companies saw between 4 and 9 percent. I know the auto industry would love to get the kind of profits that you have. But the reality is that, if people do not buy a car, they do not buy furniture, their life is not threatened. If they cannot buy your product, it may be. So that is why this is so important today. And, Mr. Gonzales, I want to specifically start with you, because Humira is the world's best-selling drug. It treats arthritis, Crohn's disease as we know, also ulcerative colitis. And you introduced the drug in 2003, and in 2017 it generated $18.4 billion in revenue. And if Humira was its own company, it would be among the Fortune 500 companies all by itself. So let us talk about this, because the average person on Medicare is earning $26,000 a year. The price of your drug started high and has gone higher, to a point now where it is as much as $50,000 a year. So, Mr. Gonzales, your primary patent expired in the U.S. in 2016. Is that correct? Mr. Gonzalez. That is correct. Senator Stabenow. And you have more than a hundred other kinds of patents for processes and techniques and so on. In fact, according to a report, ``Broad U.S. Humira Patent Estate,'' some of the patents go up to 2034, which gives you about 31 years of patent protection. That is a pretty good deal on this successful drug. When we look at what is happening around--well, let me first ask this. Has the drug itself gotten any better with all the new patents? Mr. Gonzalez. I think as you look at the evolution of the patent portfolio that is around Humira, it is important to keep in perspective that that patent portfolio evolved as we discovered and learned new things about Humira, in particular, as we discovered that this particular molecule could be utilized across a large number of different disease states. Senator Stabenow. And I am going to, unfortunately, in the interest of time--I appreciate that and would want to follow up in writing, but as I understand it, the chemical formula is the same. And so it is a question of how we use the patent system. But to look at, in Europe, when your patents expired in the fall of 2018 and biosimilars came out on the market, your prices there were already lower than in the U.S., but now you are offering, I understand, up to 80 percent discounts to be able to continue to compete in Europe. Why do you not--with all of the support from American taxpayers on this drug, why do you not offer the same low price to American families? Mr. Gonzalez. Because Humira plays a very important role in AbbVie's overall funding of R&D. And I think it is fundamentally underpinned by the fact that if you look at these inventions that we have created, that were patented, as I said, they included a number of different diseases for which Humira was effective, and they evolved over time. We think we have struck a reasonable balance. We have now licensed seven biosimilar players to the entire portfolio. So they can use that portfolio to go out and copy Humira. We have given licenses to them, and they will all enter the market in 2023. The earliest patent to expire in that portfolio is June of 2022. So, literally seven biosimilars will come within a year. Senator Stabenow. Mr. Gonzales, I know my time is up. Let me just say, I think that you charge more here because you can. And American taxpayers are subsidizing all of you to be able to have incredibly high profits, the fastest-growing part of the health-care system. And I think the people in Michigan and across the country deserve better. They need to be able to afford the medicine and not have to go to another country to get it. The Chairman. Senator Cantwell? Senator Cantwell. Thank you, Mr. Chairman. I wanted to get feedback on the market-type mechanisms and whether they would drive down costs to purchasers and to consumers. So concepts like allowing States to negotiate on behalf of a population for health-care plans, like the basic health plan in New York--do they drive down cost? [No response.] Senator Cantwell. No one wants to take that on? Mr. Frazier. Thank you, Senator. I did not know who the question was addressed to. I think first of all, it is important to recognize that there is no single market for drugs in this country. So for example---- Senator Cantwell. We are on limited time, and I appreciate the chairman's great efforts. No, I am just trying to get ``yes'' and ``no'' answers whether these concepts drive down costs--whether you believe they do. If it is a hard question to answer, it just tells me something about how willing you are going to be to help us with this problem. So my point is this. States negotiating on drug prices on behalf of a group of citizens, does it drive down prices for consumers in your opinion, ``yes'' or ``no''? Mr. Frazier. I would have to say, depending on the system, it could very well do that. But I think it will do that at the expense of a system, for example, our Medicare system that has come in at 50 percent of what it was projected to be. I want to come back to an issue that was raised at the beginning about the affordability, if you will just allow me. A significant issue in our system is that patients pay 13 percent against the list price for drugs when they pay 3 percent against a lower negotiated price for other medical services. I think the primary issue in our country now is out-of- pocket costs--13 percent is much higher than 3 percent. And if we were designing a system, we would never design a system that actually taxes the sicker people to pay for the healthy people. Senator Cantwell. Okay. I am asking a really basic question. Like the VA's ability to negotiate on drug prices, do you think that States having that same ability drives down price? Mr. Frazier. I would say that the VA would get a lower price and the States would get a lower price if you are willing to go into an environment where that could be imposed by States. Senator Cantwell. Well, or the Federal Government. But in one example--which I think you are familiar with, because I do think you are involved with hepatitis C drugs--Washington's Medicaid program is continuing to think about a Netflix model where you buy the best, the lowest per-unit costs, and cover more people. Do you think that model works in driving down costs to consumers? Mr. Frazier. I think that could work to drive down cost to consumers, no question, as long as you have the State ``negotiating.'' I would object to the word. Very frequently, when we deal with governments outside the United States, people use the word ``negotiations.'' Those prices are imposed. Senator Cantwell. Well, someone who is negotiating on behalf of the patients they are trying to cover negotiates with you or other drug companies on whether they are going to meet that discount. They are using market forces of bundling up and leverage. I call it a Costco model. If you buy in bulk, you get a discount. We are clearly doing it with the VA. The question debated here is whether we should spread that out to cover more Federal programs, which is what is being done in Canada, and whether we should use those same market forces in allowing States to negotiate, at least for the working poor in this country, a better deal than they can get because they work for employers that do not cover them. So I think if you guys cannot even agree that these basic market functions that allow people to buy in bulk and get a discount are good ideas for consumers, then I do not think you are going to come up with anything we are going to agree on here, because these are market functions, basic market functions. Does anybody else want to add whether they believe in these market functions? Mr. Gonzalez. Yes, Senator. I would just illustrate one point. I think your point is a valid one for the overall system costs, but I think what Mr. Frazier was describing is a critical issue. There are two affordability issues here. There is the affordability to the system, and there is the affordability to the patient. Both have challenges, but the affordability to patients now has really gotten out of hand. I will give you an example, my HCV example. We cut the price by 72 percent, the list price by 72 percent. The out-of- pocket cost in Medicare is $3,250. The same patient who could not afford the out-of-pocket cost at $7,000, unfortunately cannot afford $3,250. Senator Cantwell. Well, I will tell you what is absurd is the fact that you got a $6.3-billion tax break in the last tax bill and you cannot even say that you are for basic market functions like giving people discounts when they are bundled and you get volume. So I guess we will have a tough time coming to something-- but I know people here are going to want basic market functions to drive down costs for consumers. Thank you, Mr. Chairman. The Chairman. Senator Cornyn? Senator Cornyn. Thank you, Mr. Chairman. Mr. Gonzalez, I want to focus on Humira. Obviously it generates about $18 billion of revenue for your company each year. Is that right? Mr. Gonzalez. That is correct. Senator Cornyn. Please understand that I get it. We want to make sure that we maintain the most innovative pharmaceutical drug companies in the world, because we want to provide lifesaving cures for our people. And I get the idea that that is the purpose of the patent system, which is to protect the exclusivity of that drug that you have sunk a lot of money into the research and development for. And I support our patent system. I think it is very important. But what I do not understand is, according to my information here, Humira has 247 patents. And some of those patents do not expire until 2034. As Senator Stabenow pointed out, Humira first was sold to patients in 2003. So is it your company's position that it should have an exclusive monopoly on that medication for 31 years? Mr. Gonzalez. Senator, no, it is not. It is essentially that the patents cover innovations that we created. And I think one of the things that has been lost here is, it does not matter how many patents you have--and those are applications that you described, not actual patents. But there is a large portfolio of patents. It has 136 patents, and together---- Senator Cornyn. So you have 247 patent applications, but you have 61 patents? How many patents do you---- Mr. Gonzalez. No. I am sorry. A hundred and thirty-six patents. Senator Cornyn. A hundred and thirty six patents on one drug? Mr. Gonzalez. But well, remember, Humira is like 9 different drugs or 10 different drugs. So---- Senator Cornyn. I thought you said to Senator Stabenow it was the same molecule. Mr. Gonzalez. It is the same molecule, but it treats different conditions. And if you look at that patent portfolio---- Senator Cornyn. So you use the same molecule to treat different conditions, and you can get a patent on that treatment? Mr. Gonzalez. Certainly. Now, an example of one of the areas that got a significant number of patents is inflammatory bowel disease. After we developed it for RA, we realized that Humira might work in that area. That was an area that was under-treated. Most drugs had failed. We did 20 clinical trials to determine how to make Humira work in those patients. And we were issued a large number of patents for the discovery work that we did in that area. But in the end, the number of patents is not something that protects a product. If a competitor wants to make a generic version of a product--there are patents everywhere. The question is, does the invention stop the biosimilar player from making the product? If the invention does not, the patent is meaningless. If the invention and---- Senator Cornyn. The patent gives you an exclusive right to produce a drug. Mr. Gonzalez. No, we do not block any biosimilars. Biosimilars can make the product---- Senator Cornyn. No, no. Maybe you misunderstood. A patent, during its term, gives you exclusive rights to produce a drug. Correct? Mr. Gonzalez. No. Senator Cornyn. No? Mr. Gonzalez. No. The composition-of-matter patent would give you exclusive rights to produce the drug. But the patents that are covered in this portfolio are for individual innovations that were created. And in many cases, when we go into an area, there are always patents. The first thing you do is, you look to see, can I design around those patents? If ultimately you determine you cannot design around those patents, then you go to the player who has the patent and you negotiate a license. And we have now given license to virtually every single biosimilar player--with the exception of one--and we have done it literally 10 years before the last patent expires in that portfolio. So we have tried to strike what we think is a reasonable balance. I realize it may not be popular, but I think it is a reasonable balance. Those---- Senator Cornyn. But what I am concerned about is--as I told you at the outset, I support drug companies covering a profit, based on their R&D and their development of innovative drugs. But at some point, that patent has to end, that exclusivity has to end so that the patients get access to those drugs at a much cheaper cost. It is true that you, your company, blocked Amgen for a number of years from seeking to produce a Humira biosimilar or equivalent; correct? Mr. Gonzalez. Amgen has a license in the United States right now to be able to produce---- Senator Cornyn. But you blocked them for 5 years, right? Mr. Gonzalez. No, we did not block them. Senator Cornyn. You sued them. Mr. Gonzalez. They came to us, and they wanted access to the portfolio that we had. And we licensed them. Senator Cornyn. Did you sue them? Mr. Gonzalez. We did, yes. Senator Cornyn. And you entered into an agreement with them that accommodated both your needs and their needs, I assume. Mr. Gonzalez. We licensed them a patent portfolio. They pay us a royalty on the patent portfolio when they come to market, and that is essentially just like any other license. Senator Wyden. Mr. Chairman, I do not want to interrupt. Senator Cornyn is dead right, and that is exactly the same point I was going to make. Senator Cornyn. Mr. Chairman, could I just make a suggestion that---- The Chairman. Go ahead. Senator Cornyn. I know this topic is within the jurisdiction of the Finance Committee, but those of us like you and me who are also on the Judiciary Committee, which has jurisdiction over the patent system, I think this is an area that we need to look into through our Judiciary Committee authorities as well. The Chairman. Why don't you take that up with Senator Graham, and I will make sure that I back you up on it. Senator Cornyn. I will look forward to your back-up. The Chairman. And let me know what your conversation produces. Senator Cornyn. Thank you. The Chairman. The next four would be Menendez, Thune, Carper, and Isakson. Senator Menendez? Senator Menendez. Thank you, Mr. Chairman. Let me say a few words before asking some questions. To the New Jersey companies here today, thank you for coming. I am proud our State is at the forefront of innovation. But even in New Jersey, where the pharmaceutical industry and related fields like medical research employ hundreds of thousands of people, the overwhelming majority of the more than 9 million New Jerseyans believe drug prices are too high. And so I think we all have to be responsive to that challenge collectively. Americans everywhere reject the notion that reducing prescription drug costs means reducing innovation. They are uniting around this issue. And it is not a Democratic or Republican priority. It is bipartisan. Maybe it is for political reasons, but President Trump is talking more and more about executive action. A Republican chairman of the Finance Committee, Senator Grassley, has convened this hearing today, the second of two on prescription drugs. And reducing prescription drug prices has become a focal point of virtually every Democratic presidential campaign. So consider it a friendly warning from someone who believes in the hope that you provide patients in need of new cures and treatments: it is time to be proactive, because if you do not make the meaningful action to reduce prescription drug prices, policymakers are inevitably going to do it for you. So I just hope you will take that to heart. Let me ask you, many corporations--not just pharmaceutical ones--received a huge windfall from the Trump tax bill. Your companies spent well over $40 billion buying back your own stock in the past year. Going down the row, can you just give me the ballpark number? Did any of you use your tax breaks to lower the costs of any of your prescription drugs? Mr. Gonzalez. We did not use our tax break to lower the cost of prescription drugs. We used it for other aspects of trying to stimulate the economy and invest further in the United States. Senator Menendez. No, you did not use it to lower the cost. Mr. Soriot. Senator, the tax break for us, being based in the UK, had a very marginal impact on our profitability. So I think the question is---- Senator Menendez. The question is--it is a simple ``yes'' or ``no.'' Whatever the tax break was, did you use any part of it to lower the cost of prescription drugs? Mr. Soriot. Well, the cost of our prescription drugs on the net basis has been declining for many years now. Senator Wyden took---- Senator Menendez. I am sorry to interrupt you, Mr. Soriot. It is a simple question. Did you use any part of the tax break that you got to lower the cost of your prescription drugs? Mr. Soriot. In a roundabout way, yes, we did, because the minimal tax benefit we got helped us sustain our profitability at the same time as our prices were declining. Senator Menendez. Dr. Caforio? Dr. Caforio. We did not. Ms. Taubert. Hello, Senator. It provided us the opportunity to invest an incremental $30 billion in R&D and capital investments in the U.S. over the next 4 years. We think that that is the best way for us to be able to deliver for patients. Senator Menendez. Mr. Frazier? Mr. Frazier. Senator, our effective tax rate went up from 19.1 to 19.8 percent. Dr. Bourla. We did use this tax break to do many things, among them reduce our prices. Prices in 2018, for the first time since I remember, went down at Pfizer. Dr. Brandicourt. As a French company headquartered in Paris, we did not get much from the tax break. On the GAAP basis, we lowered our global tax rate by 1.5 percent. Senator Menendez. All right. Now, in November 2017, FDA Commissioner Scott Gottlieb called on pharmaceutical companies to ``end the shenanigans when it comes to the ability of potential competitors to purchase branded doses at full market price.'' He stated, ``I see this clearly, for example, in steps branded companies sometimes take to make it hard, or altogether impossible, for generic firms to get access to the doses of the branded companies needed in order to complete bioequivalence studies that the FDA requires for a generic approval.'' I have co-sponsored legislation called CREATES that ends the gamesmanship by certain companies, where they prevent generic manufacturers from accessing the necessary samples they need to develop generics. Last year the FDA published its first list of medicines that generic companies have had trouble accessing. That list includes more than 170 complaints covering 50 medicines. So can you go down the line and tell me, ``yes'' or ``no,'' does your company in any way restrict access to, or block the purchase of samples at full market price? Mr. Gonzalez. No, we do not. Mr. Soriot. No, we do not. Dr. Caforio. We do not. We support the current version of the CREATES Act. Ms. Taubert. No, we do not. Mr. Frazier. No, we do not. Dr. Bourla. No, we do not, and we support CREATES. Dr. Brandicourt. No, we do not, and we support CREATES too. Senator Menendez. I have other questions. I am going to submit them for the record. Thank you. The Chairman. Thank you. Senator Carper? Senator Carper. Thanks to each of you for joining us today. My wife lost her mother when she was 11 years old. My wife said it put a hole in her heart. She has never gotten over it. My own mother, her mother, and her grandmother, by the time they were 80, they did not know who they were, or where they were, or who we were. For all of us this is personal, and it is political, and it is economic. When we have a hearing of this nature, one of the things I like to do with disparate witnesses like these--you are all from the same industry, but you have different views, come from different parts of the world. But I am going to, in a minute, give you--what I am looking for is consensus. What I think we are looking for is consensus agreement on what is the right thing to do to make sure that what we are producing is effective and affordable for us, for the government, for our constituents. I am going to give you three items and ask you to tell us what you think. If we do nothing else, those three items, we can all agree on those. Okay, and I will give them to you right now. The first is eliminating rebates to PBMs. That is the first one: eliminating rebates to PBMs. The second is value-based arrangements. And the third is increasing transparency industry-wide on how you set your prices--increasing transparency industry-wide on how you set your prices. If you would like to take a moment--and we would just start with you, Mr. Gonzalez. We will just start with this question first and see if we have time to get it done. I hope we do, those three. Mr. Gonzalez. I would say that we clearly support providing the discount at the patient level, so eliminating rebates, essentially. We absolutely support value-based pricing, because that is the business we are in and the kinds of diseases we are trying to treat and cure. And we absolutely support transparency. And I would say transparency even more broadly across the entire system, including everyone that is in the supply chain. And that would also include where government rebates are, such as the 340B program. We would support total transparency across that. Senator Carper. Thank you. I would ask each of our other witnesses to also keep your responses short. Mr. Soriot? Mr. Soriot. Senator, I would give the same responses. We support all three items. I would go one step beyond, which is if the rebates--as I said earlier--were to be removed from Part D and the commercial sector, we would actually reduce our list prices by the rebates' amount, less the fees that are probably single-digit type fees to be paid to wholesalers and other stakeholders in the system. Since you talked about a disease that is very common and becoming more common and a tragedy for people who suffer from it, Senator, I would just like to say that, as Mr. Frazier said a bit earlier, his company spent a billion dollars on developing a drug for Alzheimer's. Our company together with Lilly, we spent $900 million to try to develop an Alzheimer's drug that failed. And that is a really good reminder of the risks that we take as an industry. We spent $900 million, many years of work, and at the end of the day, nothing. Senator Carper. Thank you. Dr. Caforio? Dr. Caforio. Yes, Senator. First of all, I am very sorry-- -- Senator Carper. Please be very brief. Dr. Caforio. I would say that not only do we support all three elements that you mentioned, but I do believe those three elements together with the continued effort to develop a generic and biosimilar market would mean significant change, and would clearly alleviate the concerns that patients have today. Senator Carper. Great. Thank you, sir. Ms. Taubert? Ms. Taubert. Senator, first of all, I am very sorry for your wife's family and also for your family. It underscores---- Senator Carper. While I said that, everybody in this room could probably point to similar experiences. All of us have had them. Ms. Taubert. Absolutely. Senator Carper. Thank you. Ms. Taubert. We are very supportive of all three elements that you outlined. So the elimination of---- Senator Carper. That is all I need. Ms. Taubert. Perfect. Senator Carper. Thank you. Mr. Frazier? Mr. Frazier. We too support all three. Senator Carper. Thank you. Dr. Bourla. Senator, all three elements are transformational for our industry, will disrupt it. However, we do agree that these are the three things that need to be done, and also I believe that they will have significant, meaningful results if we do them. Senator Carper. Thank you, sir. Dr. Brandicourt. We strongly support the three, Senator, but we want to keep in mind at the end of the chain, the patient has to benefit. So if rebates are removed, it has to be to the benefit of patients. Senator Carper. Good. Thanks. Mr. Chairman, I am going to do a follow-up question in writing, asking your responses, your reaction to what is going on in Germany on this front--what do you like about it, what concerns you might have about it. But that is a different question, but it relates to this discussion. Thank you. The Chairman. Before Senator Thune goes, can I ask Dr. Caforio, did you say you support the CREATES Act as well? Dr. Caforio. I did, Chairman Grassley. The Chairman. Thank you. As sponsor of that, I appreciate that very much. Dr. Caforio. Thanks for your work in that area. The Chairman. Senator Thune? Senator Thune. Thank you, Mr. Chairman. I would like to ask unanimous consent to insert for the record a one-page document from 340B Health that shows that manufacturer discounts account for less than 2 percent of the total drug market. The Chairman. Without objection, so ordered. [The document appears in the appendix on p. 1,053.] Senator Thune. Thank you. Each of you has referenced the recently proposed rebate rule, which outlined several different scenarios of how drug companies and others would react, as well as the impact on Part D premiums. Mr. Frazier and Dr. Bourla, if the rule were finalized, could you please discuss how you would set list price and how your negotiations would work with others in the supply chain? Mr. Frazier. Okay, assuming that--as I said when I answered the question before, assuming that we do change the systems on the commercial side and the Medicare side so that no one company faces a disadvantage, we would be lowering list prices. We have been asked to lower list prices. We have lowered list prices in the past and found that it creates a financial disadvantage for the company, and it does not get us more volume because of the incentives in the system. So if we change all the incentives at one time, then list prices can come down. Senator Thune. Dr. Bourla? Dr. Bourla. Fifty percent of the American people are in commercial plans, and these rebate rules apply to Medicare. If the rules apply to all, definitely the list price will go down. But also, during the Medicare-only application, we pledge and we commit that every single dollar will go to the patients. As the chairman said, the list price is not irrelevant. It is very relevant for a lot of people, because they have to pay list price during the deductible period. However, if the rebate rule is applied, then it becomes irrelevant because the patients will not be paying the list price at the purchase point. And this is a significant win. What I want to say is that, even if we do not move it to commercial, which I overwhelmingly support, I think it is a significant win for the American people if we do it even in Medicare only. Senator Thune. So Medicare-only would be an improvement, but you pointed out in your testimony the challenges associated with the bifurcated market with respect to rebate reform. So how would manufacturers respond if the rebate rule were finalized for government programs? I mean, what does that mean for the commercial market? Dr. Bourla. Senator, as I said before, all these proposals we are discussing, including eliminating the rebate rule, are transformational and will disrupt the way we do business. I do not know exactly how the system will evolve, and I really do not favor a bifurcated system. I would like to have a transparent, single system across both parts. So we need to see how the whole thing will evolve. Senator Thune. Okay. You have each expressed support, and this was alluded to earlier by Senator Carper, for paying for value as well as the value your medicines bring to the health-care system. I am a believer in value-based insurance design as a way to lower the overall health-care costs, and I have worked on legislation to advance this principle. As we drive toward paying for value, how do we make sure that you as drug manufacturers still have the incentives to keep your prices low and that we are not just shifting money around in the system? Dr. Bourla. I think by definition that a value-based arrangement will align the incentives, not only of us, but those of the insurance companies, around one common goal: the good for the patient, clinical outcomes, measurable clinical outcomes for the patient and the health-care system. In this case, if we fail to produce drugs through our research efforts that will have meaningful clinical benefits for the patients, yes, we will not be paid. And this system also will ensure the medicines that do not add value will be paid much much less. So to create space for medicines that do create value is the best way of aligning the incentives of everyone around the interest of the patients. Senator Thune. Does anybody else want to react to that? Mr. Soriot. Yes, Senator, if you allow me. We have an example that I quoted before. We have a product that is used for the treatment of patients who have experienced a heart attack. If you experience a heart attack, when you are discharged from the hospital, your chance of getting a second heart attack is pretty high. So we contracted with an organization and committed to reducing the percentage of patients who have a second heart attack. In return, the University of Pittsburgh Medical Center, for these Medicare patients, committed to ask these patients to pay a very low co-pay to make sure they were complying with their treatment. And that actually delivers value to the system, because patients are kept healthy. Of course, good for them, but also they do not go back to the hospital. This is how we deliver value. Senator Thune. Okay. Thanks. Mr. Gonzalez. Senator, I would just add one point. I think your point is a valid one. Look, an innovative pharmaceutical cannot capture 100 percent of the value that it saves. It has to capture less than that. And I think the way that will evolve the best is if there is strong market competition. I remember back in HCV, if you look at the health economic data around that drug, it would have suggested that you could justify a price well north of $100,000 per patient. And the prices were relatively close to that when there was one player in the market. Today prices have gravitated down to about $25,000-$26,000 per patient. It is the market force that created that, the market competition of more than one player being in that market and competing on an active basis. We were obviously part of that competition that drove those prices in that direction. So I do not think it is realistic to assume that a pharmaceutical, just because it can save $150,000, as an example, that it can charge $150,000. It has to charge less than that so that the overall system can benefit from the value of that medicine. But it has to be able to charge a price that is reasonable enough to be able to achieve and continue to fund the programs going forward. The Chairman. Senator Isakson, and then Senator Cardin. Senator Isakson. Thank you, Mr. Chairman. I thank all of you for being here. This is a terrific hearing, and we are going to have a lot of hearings on this subject. I told my staff a couple of weeks ago, I said, ``You know, I have been a solid supporter of the pharmaceutical industry all my career,'' and I have, and I appreciate all that you do. I go to work every day because of levodopa. I would not be able to be here today if it was not for the pharmaceutical industry, and I have Parkinson's disease. But I can function every day and do my job because of that, and I appreciate it every day. My first chief of staff called me Sunday night from Children's Hospital in Atlanta to say his youngest son had just been diagnosed with juvenile diabetes. His first child, a daughter, had juvenile diabetes 12 years ago. But the thing he said was, ``At least I know that you can live a normal, happy life because of insulin and because of pharmaceutical care.'' So I am not softening you up, but I am softening you up, because those are good stories that we cannot forget. And that is the value of innovation and research development, and we appreciate it. However, when you cannot explain it and you are elected to the U.S. Senate--and I appreciate your comment about how honored you are to be in the U.S. Senate, Dr. Bourla--but the fact of the matter is, when I cannot explain it, it is tough. And I cannot explain the cost increases I have seen a lot of recently. One medicine I take--I take eight a day--one of the ones I take every day went up. When I went to get my new prescription in January, it was $90 more than it was at the end of last year. I just said, ``How can that be?'' And the guy said this and that and the other. But he said, ``Let me call you back.'' He said, ``I will call you in the next hour and see if I cannot find a better price.'' In an hour's time he had four prices for the same pharmaceutical. If I did not use insurance, it was one price. If I used cash, it was another price. If I took discounts, it was another price. If you had coupons, it was another price. I do not remember the name of all of them, but I know it was very complicated, and it reminded me of my business. When I sold real estate, the price of a mortgage was not just the interest rate that you paid and the sticker price, but you take the effect of discount points and rebates and other things that go into the annual percentage rate return of the product, and that is what you are doing with discounts and with rebates, I assume. And it is going into the cost and ultimately into your product, which caused me to ask this question: who sets the discount and who sets the rebate? Pardon my finger. We will start with you, Mr. Gonzalez. Mr. Gonzalez. Thank you, Senator. I think the best way to illustrate what you are describing is to give you an example. Senator Isakson. A short example, please. Mr. Gonzalez. Okay. Humira--we raised the price in 2019 6.2 percent. The actual fall-through to the company, the realized increase in 2019, will be .9 percent. So the part in between there is rebates that have gone up and channel mix, primarily. But it does give you some idea of the massive change that can occur between list and realized price. We raised the price to try to offset inflation, merit increases that we give our employees, and increases in R&D---- Senator Isakson. So you set the discount or the rebate? Mr. Gonzalez. Well, we negotiate with payers. So managed care---- Senator Isakson. You are a supplier, though. So you negotiate with the PBMs and those people? Is that right? Mr. Gonzalez. Correct, and they negotiate aggressively. Senator Isakson. Is that pretty much true, everybody, that they are the major component between the end retail consumer price and the origin of the product? Mr. Gonzalez. Yes, Senator. Senator Isakson. Well, that seems like some place we ought to focus, because that is where the distorted numbers come in. Johnson & Johnson--and I'm sorry. Janssen, is that right? Is that the subsidiary? Ms. Taubert. Yes, Janssen; correct. Senator Isakson. In your testimony you talk about your average list price of 8.1 percent up, but an average net price change of only 4.6 percent. So, while your gross went up 8.6, your net went down 4.6 in the same pricing period. How does that happen? How does it not go up on the bottom? Ms. Taubert. Yes, and in fact in 2018, our net price actually declined 8.6 percent, so even more than that. So the intermediaries in the system are very very effective negotiators. Senator Isakson. Tell me who the intermediaries are. Ms. Taubert. Those would be the PBMs and the insurers. Senator Isakson. And the insurance companies? Ms. Taubert. Right, and they set the formularies for patients. Senator Isakson. And they are not the same, because they are two different people? Ms. Taubert. Yes, correct. And so what they do---- Senator Isakson. Excuse me for interrupting Ms. Taubert. I want to make sure I get all of this in. And I apologize. You are a nice lady, and I am being ugly to do that. But I am sorry. Ms. Taubert. I am fine. Senator Isakson. All right. We have the PBMs and we have the insurance companies. Ms. Taubert. Yes. Senator Isakson. Is there anybody else between the wholesale price by the manufacturer at the beginning and the retail price it is sold for at the end, at the drugstore? Is there anybody else that contributes to the cost, other than the discount and the rebate? Dr. Brandicourt. Several actors, Senator, in the supply chain are rewarded on the listing price: wholesalers themselves, and---- Senator Isakson. Is that a consumption bonus? Is that a sales bonus? They are rewarded for doing what? Dr. Brandicourt. Well, to be a wholesaler and distribute our products. What we need to do in order to realign the incentive is to get rid of the reward being based on a listing price. Senator Isakson. I have to stop, because the chairman is mean and he will cut me off the next time. So I will end by saying this. You answered my question, but it does point out that the one person who is not benefiting from the rebates, not benefiting from the cost negotiation, is the customer. And we are here for the customer today. We represent them. So we have to get to the bottom of this so we can have something we can explain, and they can experience. I apologize, Mr. Chairman. The Chairman. I let the Senator go because he was echoing my beliefs. Go ahead, Senator Cardin. Senator Cardin. Thank you, Mr. Chairman. And let me thank all of our witnesses. I also want to say how proud I am of the results of the pharmaceutical industry and the discoveries that you have made, innovations that you have brought to market, the impact you have had on quality of life and on cost, overall cost of health care, by the discoveries that you have been able to advance. The challenge that we all have is, why should Americans be shouldering the lion's share of the cost and burden of research and development and bringing new drugs to market? You talk about burden-sharing, you talk about the fact that there should be a fair allocation on the global market--and by the way, also within our domestic market, we know that a lot of people are being denied access to these innovative drugs because of the pricing mechanisms within the United States. So let me try to drill down on those points. Really, am I defending an administration policy? So let me break with my normal tradition and talk about the international pricing mechanism that the Trump administration is proposing that would set target prices or international pricing indexes over a 5- year period for Part B drugs pinned to the price in comparable industrial nations, phasing it in over a period of time and allowing a cushion for even higher prices in the United States. So if, in fact, these drugs are already priced competitively, that should not be a problem. But as I understand it, there are so many drugs that we pay, American consumers pay, a lot more for than consumers in other industrial nations. So why not move towards a process in which American consumers share a similar price as consumers in other industrial nations in the world, particularly on the Part B program? I think it could also be extended to Part D. The only explanation I have heard is that in some countries, it takes a little bit longer to get new drugs admitted. We are not talking about new drugs. We are talking here about drugs that already have an existing price mechanism. Or do you support it? Dr. Caforio. Senator, thanks for your question. I did mention this in my opening remarks. So I am happy to elaborate further. I think it is a very important point. So we take the perspective that we should always start from patient access to medicines. Senator Cardin. I am going to try to drill down, because I only have 2 minutes. Dr. Caforio. Thank you. Senator Cardin. So what is wrong with a model of comparing U.S. prices to prices in other industrial nations? Dr. Caforio. So 55 percent of new cancer medicines that are available to American patients are not reimbursed in at least-- -- Senator Cardin. We are talking about where there is a market price in another country, because if there is no target price, there is no price to compare it to. So there has to be a price in another country. So we are talking about drugs that are commonly available. Dr. Caforio. I believe, Senator, many of the most recently introduced drugs are not available in---- Senator Cardin. Then that would not apply. If I understand, it only deals with prices where there is a target price that already exists. If the drug is not on the market, it is not going to have a target price. But if the drug is on the market, you have a target price, and as I understand it, that would bring down the cost here in the United States. Dr. Caforio. I believe, Senator, it would be very important for us to be thinking about policies that continue to reward innovation. We do need your support to make sure that---- Senator Cardin. So you are basically saying we overpay on available drugs so that you can make more profit from the American consumer to underwrite R&D which benefits the global community. That is basically, as I understand that point--to me that is a disconnect in the pricing mechanism. I want to ask, Ms. Taubert, you are the one who mentioned the advantages of the free market in negotiations under Part D. So let me just change the equation. Suppose you were on the other side of the table. Why not allow the Health Secretary to combine the entire Medicare market in order to negotiate a larger market share to bring down costs for Medicare? Ms. Taubert. Yes, so we really believe that open competition and a free market are the right way to go for patients. Senator Cardin. But isn't market share that you can offer, as a person seeking the cost, a driver for bringing down costs? Ms. Taubert. So the PBMs and the insurers are extraordinarily effective negotiators. And they do negotiate now on behalf of Part D members quite aggressively. In fact, I mentioned our $21 billion---- Senator Cardin. And my question is, is it not true that the larger the market share, the better the price you are going to get? Ms. Taubert. The larger the market share, the better the price? It depends on a number of factors, including the number of competitors and the companies that are bidding to try to get---- Senator Cardin. If you control more of the market, isn't that going to bring down your price? I learned that in Economics 101. The Chairman. Answer the question, and then we will go to Senator Hassan. Ms. Taubert. Yes; I am not sure I understand the last piece of that question. Senator Cardin. With a larger consumer base on a drug, because you represent all the Medicare market, are you not in a stronger negotiating position? Yes, you are. Ms. Taubert. I think conceptually you could be. I would say that the PBMs and insurers are pretty darn effective right now. The Chairman. Senator Hassan? Senator Hassan. Well, thank you, Mr. Chairman. And I want to thank you and Ranking Member Wyden for this hearing today. I want to thank all of the witnesses for being here today as well. A couple of observations; one is that breakthroughs are not breakthroughs if people cannot afford the medicine that produces the breakthrough. Secondly, as you have all mentioned the importance of a viable and predictable system, it has to be a viable and predictable system for patients. And right now it is so convoluted and so non-transparent that my constituents cannot figure out what the price of their medication is going to be day to day. And despite a wonderful staff, I feel like I need a Ph.D. in prescription drug pricing to understand how the heck this industry works. And that should not be the way we proceed in this country to get these breakthroughs to people. But I want to talk about a slightly different aspect of your industry right now. We have been talking about drug pricing, which is one part of how drug companies make money. The other part is how you maximize sales. So, Ms. Taubert, I would like to focus on how your company maximizes sales for a particular class of drugs--opioids. Can you define for me please, Ms. Taubert, what pseudo-addiction is? Ms. Taubert. I am sorry. I am not sure. I am not familiar with that term. Senator Hassan. Let me fill you in, then. Pseudo-addiction is an unproven and dubious concept that asserts that certain patients present signs of addiction because they were prescribed insufficient doses of opioids. Those peddling this pseudo-addiction concept say that instead of providing addiction treatment when somebody shows the signs of addiction, the doctor should increase their opioid doses. Even one of the original doctors who pushed this theory now admits it was ``an excuse to give patients more drugs.'' He has told us that Janssen promoted this made-up concept of pseudo-addiction on a website that it approved and funded that was called ``Let's Talk Pain.'' Since then, your company has repeatedly said that your action ``in the marketing and promotion of our opioid pain medicines was appropriate and responsible.'' So, Ms. Taubert, how can you possibly claim that promoting the theory of pseudo-addiction--the doctor should prescribe more opioids to patients showing signs of addiction-- was appropriate and responsible? Ms. Taubert. Senator, thank you so much for that question. Abuse and addiction, particularly opioid abuse and addiction, are very serious public health concerns, and we recognize the impact on the American public. Senator Hassan. So then the question is--and again like everybody else, I have only a few minutes here. The question is, looking back at what your company did promoting pseudo- addiction--an unproven theory that was just used to maximize sales of a deadly drug--why is that something that you are calling appropriate and responsible? Ms. Taubert. So, I am sorry. I am not familiar with the term. What I can say is, on behalf of our company, opioids represent less than 1 percent of our product. Senator Hassan. All right, let me stop you right there, because my constituents do not care about the percentage. They care about the behavior to maximize sales in an industry. Do you know how many Americans died from drug overdoses in 2017? Ms. Taubert. Far too many. Senator Hassan. It was 70,237. In 1 year, more Americans died from drug overdoses than died fighting the entire war in Vietnam. And the vast majority of those overdose deaths, about 50,000, were from opioids. My constituents are dying. Nearly 500 people in New Hampshire died from overdoses last year. And nearly 500 the year before that. And companies like Janssen and Purdue Pharma fueled this epidemic, employing deceptive and truly unconscionable marketing tactics despite the known risks so you could sell more drugs to maximize your profits. And now you are refusing to take responsibility for your company's role in this crisis. So one more time, do you truly think that Janssen's opioid marketing practices were appropriate and responsible, or will you finally take responsibility for your company's role in helping create this crisis that is killing more than 100 Americans every day? Ms. Taubert. Everything that I have seen leads me to conclusively believe that everything that we have done with our products, when we promoted opioid products, which we stopped marketing a long time ago, was very appropriate and responsible. However, that being said, we do believe that we have a leadership position to take in helping with this. And so we are doing a number of things in terms of mothers and babies, and physician and patient education to help---- Senator Hassan. So let me--again---- [Simultaneous speech.] Ms. Taubert. We recognize we all play a part in trying to help this, because we realize that---- Senator Hassan. Our time is done, but right now it is hard for me to take the industry's goal here as promoting good health seriously when its behavior to maximize sales of opioids created an epidemic. The Chairman. Senator Lankford? Senator Lankford. Thank you, Mr. Chairman. Thank you all for being here. And there are people alive in the United States, around the world right now, because of your companies and the work they have done with R&D along with the National Institutes of Health. And I fully acknowledge that, and I am grateful to the people who are researching and working right now, who are not watching this hearing because their face is in a microscope actually going through things to be able to research today and what they are doing. With that said--it is all of us who acknowledge that. We are trying to figure out the issue on drug pricing, because people in my State, whether they are on insulin or whether on Parkinson's drugs, or whether my own family or other people in my neighborhood, it is a very significant issue for them to try to figure out how to be able to manage this. So we have to get to the bottom of how we manage this. All of you have mentioned that the rebate issue has been a problem and that insurance companies and PBMs are very effective negotiators. Part of the challenge of this is, health insurance companies pay their PBM based on the quality of their negotiation skills, cutting a price off the list price. And so, if a list price is higher and a rebate is higher, that also gives preference to them. So the difficulty is, as you raise list price and the rebate gets larger, the insurance company gives that preference, making it harder for biosimilars. Am I tracking this correctly? So the challenge that we have with this is, how do we figure out how to break this down? Because we have insurance companies, PBMs, your companies that are creating the list prices, and then the biosimilars trying to be able to get into this. So, Mr. Frazier, you mentioned this, in particular about biosimilars and the difficulty of trying to be able to break into the market. Would you identify why it is hard for biosimilars to get into the market, which are inherently less expensive? Mr. Frazier. I would make two suggestions very quickly, because I know you only have a little bit of time here. One is, I think we have to educate physicians and other health-care providers about the value of biosimilars. I think, secondly, it would be very helpful if we could relieve patients of their obligation to pay copays for the cheaper biosimilars. Those would be two specific recommendations that I would make. Senator Lankford. Thank you. I appreciate that. For the Part B drugs, those physicians are paid a percentage of the drug costs. So a biosimilar, when it comes into the market in the Part B world, is, on its own, less attractive to a physician because a physician gets a higher percentage amount prescribing the more expensive drug, which then feeds down to the patient and the taxpayers, right? Mr. Frazier. That is correct. Senator Lankford. How do we break that chain? Mr. Frazier. I think that we--there are many ways that we would have to look at it. I do not have a specific suggestion here. I do think educating physicians is important here, and I think relieving patients, but we also have to look at the incentives. Dr. Bourla. Maybe I can---- Senator Lankford. Dr. Bourla, please jump in, because you had mentioned this in your testimony as well. Dr. Bourla. I did, Senator, and thank you for giving me the opportunity. Let me give you a statistic that I think will present the magnitude of the problem. Here in the U.S., the penetration of biosimilars is much lower than in other places, but it is disproportional to different parts of the U.S. health-care system. For example, in open systems, systems where the decision- maker is a PBM, one biosimilar or two has a market of 5 percent in the U.S. In closed systems, in systems like Kaiser, for example, with their integrated health-care systems--where the one who decides has the whole cost of the health-care system in its interest--we have 73 percent. Five percent versus 73 percent for the same product. I agree with what Mr. Frazier said, that we need to create incentives, but I would add also that we need to break this rebate trap that creates significant disincentives for providers, and the health-care system, and insurance companies. Senator Lankford. Does anybody else want to jump in on that? Dr. Brandicourt. I can give you an example, Senator. The insulin market has a reputation of not being very competitive. In fact, it is, and we have biosimilars which have reached the market and have grabbed a very significant market share. We believe that when insulin will not be treated as a drug, but will be considered a biologic and can be submitted to biosimilar regulation in 2020, the biosimilar market share and penetration will be even higher. Senator Lankford. Thank you. My State, in particular, is working very hard on our Medicaid side, working on value-based pricing. I know that is something that several of you have mentioned before. It is the grand challenge of not pricing a drug based on the fact that it would be more expensive to do surgery and so we want to be slightly under the cost of surgery. We do have to be able to break through that model. Of course surgery would be more expensive than most of our treatments, but I think there is a benefit that we continue to experiment with if the drug is effective and we have a reducing price on it. And we can get a chance to be able to work through that, as we have done in our State. Mr. Frazier. We would support that. Senator Lankford. Well, we will continue to be able to work through other creative mechanisms. At the end, we cannot just have the taxpayer pay more and the consumer pay less, because that is really the consumer still paying. It just moves it to another spot. Mr. Chairman, thank you. The Chairman. Senator Cassidy? Senator Cassidy. First, think of innovation. As a doctor, I have seen cures for hepatitis C and therapies to control HIV, other inflammatory conditions, cancers that 30 years ago, when I graduated from medical school, were either death sentences or were a ticket to a lifetime of morbidity and complications. So I thank you for that. But I also say that some of my patients could not afford the medicine. And for them, it is as if the innovation never took place. And that is one concern. Secondly, another concern is, I think in some cases we do not have value. Now, Ms. Taubert, you suggested that PBMs are very effective negotiators. One drug that I want to bring up is Duexis, which is a combination of over-the-counter generic ibuprofen and Pepcid. Now, if I were to take this--and this is not the cheapest I could find it--in the doses that are used for Duexis, it would cost me 200 bucks a month. But it lists at over $2,400 to $2,600 a month. Now, that does not seem like very good negotiations on behalf of the PBM. And if the taxpayer is paying that money for something which over the counter is 200 bucks a month, and we are paying $2,600 a month, it is almost as if the taxpayer has ``stupid'' written on their face, which they should not. That is unfair. This is not your medicine, but I use it to make the point that, right now, Medicare has a very limited ability to negotiate based on marginal value. And I think that is one of the fundamental problems in this. So that said, all things considered, since Medicare does have this very low ability, Ms. Taubert, do you think that Medicare should have the ability--if the PBM's negotiation does not work--should Medicare have the ability to negotiate based on value? Ms. Taubert. So we are very supportive of the notion of value-based contracting and results and---- Senator Cassidy. This is a little bit different though, because we have been describing, on value-based contracting, is the cancer cured or not, is the hepatitis C cured or not? This is, my gosh, you are taking two generic medicines and charging ten times what they would cost over the counter. Ms. Taubert. Yes, and I agree that that example does not make any sense. Senator Cassidy. So is it reasonable then to ask that Medicare would have the ability to make some sort of judgment based upon relative value of a therapy? Ms. Taubert. I think, as we have talked about, if the PBMs are very effective in negotiating, we do not know that the government would be as effective in negotiating as the professional negotiators. Senator Cassidy. We do not know. I agree with that, but on the other hand it does--I have limited time. I do not mean to be rude. I do apologize. But there is this kind of shining example of where the PBM is not an effective negotiator. Yes, sir, Mr. Frazier? Mr. Frazier. I think this is where Chairman Grassley's opening statements about transparency come in. I think one of the keys of transparency is, it empowers patients and it empowers other payers to actually make informed choices about which of those two medicines makes sense. Senator Cassidy. Now, let me ask, because someone brought up the fact that Humira is now sold at an 80-percent discount in Denmark. And there is a Bernstein analysis which states that AbbVie still makes a profit because marginal cost in manufacturing is only about 5 percent of the manufacturing. So would this same entity have the ability to look not just at value, but at comparable drugs and at that which would bring value, because clearly biosimilars have had a much greater penetration in Europe, and the United States continues to pay top dollar for the same class of drugs. Something is fundamentally broken in our system when the Danes get an 80- percent discount and we do not. Yes, sir? Mr. Frazier. I think we have to look at the way in which generic penetration happens outside the biosimilars market. When a drug goes off-patent---- Senator Cassidy. Well, hang on, Mr. Frazier. I am sorry. I just get limited time, and I am going to hold you on that. Okay, I do not mean to--one of the things I have heard is that, if there is some limit on that profit, it may have a negative impact upon R&D. I think that has been a message here. But, Dr. Brandicourt, France has a committee on transparency which evaluates the relative added clinical benefit of a new drug. Price is then negotiated based upon that added benefit as well as other drugs in the market. Is it safe to say that your company has found that it still pays to innovate and to do R&D in France and to offer them access to the best cutting-edge drugs? Dr. Brandicourt. As a global company, we do have R&D in France. However, I would not use the French system as the benchmark of a good system. Senator Cassidy. But they do have access to these--I have limited time. I am sorry. They do have access to these drugs? Dr. Brandicourt. Well, that is a very good point. Some drugs are not put on the market because you do not get to the right pricing and therefore the right---- Senator Cassidy. But if I am--I will finish with this. I do not mean to be rude. I apologize. In the international pricing index, we may quibble about the details, but if the U.S. would be paying 1.3 times a market basket of developed countries--a Germany, a France, a Canada, not smaller countries--we would still be paying more than they, but it would still have some relationship to reasonableness. And right now, it seems as if Medicare--in the absence of the ability to judge value--is almost a price taker when it should not be, as the largest purchaser. Dr. Brandicourt. You would ask countries where there is no negotiation, where prices are imposed, to set up your U.S. pricing. And I do not think that would be good policy. Senator Cassidy. It is imposed now, but it is imposed from the other side. The Chairman. Of the people who are still here, Bennet would be next, and then Whitehouse, and then Cortez Masto. Go ahead, Senator Bennet. Senator Bennet. Thank you, Mr. Chairman. Thank you so much for holding this hearing. There is not a town hall in Colorado where I do not hear how expensive drugs are forcing people to choose between life- saving treatments or food and utilities. In our last hearing here, we heard from a mother whose son ate once a day in order to ration his insulin, because the full cost of the monthly treatment was $1,700. I do not think anybody here understands how that could be the case, but it is the case. And there has been a lot said here today about the important research and development that is going on in this country. And I, for one--and I know others share this view-- want to keep that in the United States. Having said that, I am trying to understand how Federal spending goes into prescription drug development, distribution, treatment, and pricing and yet Americans cannot afford their medications. The estimates of annual spending on prescription drugs range from $320 to $480 billion a year. The fact that we cannot even get a more precise number than that tells you something right off the bat, but those numbers include almost $100 billion in Medicare Part D spending never paid for. Of that, $25 billion is in Medicare Part B. Medicaid spends almost $60 billion on prescription drugs. This is what the taxpayer spends every year on prescription drugs. DoD and VA spending is about $11 billion. That number alone dwarfs the R&D budgets of some of your companies. Over 6 years--slightly different point--but over 6 years between 2010 and 2016, more than $100 billion was spent in NIH funding toward research that contributed to drug patents. Between $1 and $2 billion is claimed annually through the orphan tax credit for drugs that treat rare diseases. Another $1 billion is annually claimed through the research and development tax credit. About $12 billion dollars is claimed annually through the direct-to-consumer advertising tax credit. I would ask you guys if I missed anything, but I think that is a pretty complete list of what we have. Yet notwithstanding that almost $500 billion, half a trillion dollars--by the way Medicare, you know, to spend all that money in Medicare, we are spending $2 for every dollar we are collecting. That delta is largely because of drug prices in the unfunded part of Medicare Part D. And here is what Coloradans have recently reported. In a recent survey on high drug prices, 22 percent did not fill a prescription, and 20 percent reported cutting pills in half or skipping doses. Seventy-four percent believe drug companies are charging too much money, and 91 percent believe the government should authorize the Attorney General to take legal action to prevent price gouging or unfair prescription drug price hikes--over 90 percent. And that does not necessarily give you their legal judgment, but that is how keenly they are feeling the problem. And 90 percent believe the government should require drug companies to provide advance notice of price increases and information to justify those increases. So, I would ask all of you, or anybody who would care to answer, this question: how do we explain to our constituents on the one hand that we have this massive outlay of Federal funds, it is their taxpayer funds, and the on the other hand, the drugs they are buying are not affordable? And I realize there are all kinds of layers to this. I accept that. You know, there are the higher co-pays that you guys mentioned earlier from the insurance companies. That is a huge issue too. But I think that in a world where opacity or opaqueness has been, from the public's point of view, a business model for everybody in health care, whether it is the Federal Government or drug companies or insurance companies or doctors, nobody knows what anything actually costs. Nobody knows what anything will pay. My question, I guess, is, how do we better align the incentives here so that that huge outlay of money every year comes with affordable drugs at the end of the process? Mr. Gonzalez, thank you. Mr. Gonzalez. Senator, I can just tell you there is probably not anybody at this table who does not agree not a single American should go without drugs that they need. And I can tell you, that is the case at AbbVie. We do a lot of things to try to provide drugs for patients who cannot afford them. But there are certain patients whom we are unable to do that for based on the laws and the regulations, and in particular, most of Medicare Part D falls into that situation. And so I believe fundamentally we have to do two things. There are substantial discounts or rebates that are going into this system. Take Humira as an example. In the United States, there are rebates or discounts on that product that range from 87 percent down to 26 percent. Okay, and it is the Federal Government that gets the highest form of discount or rebate on Humira, even though it represents a relatively small percentage of the volume, less than 20 percent of the overall volume. Now that does not mean that we could not do more. But what we are asking is, we do believe that there is a situation now where the co-pays for patients are such that it is extremely difficult for them to afford it. And what we are asking for is--``we,'' meaning AbbVie and I am sure others here, would like to do more. There is more we can do to help patients afford their medicines, but we have to eliminate some barriers that are blocking that. Today we give away to 81,000 patients free drugs; half of those are Humira. Of those Humira patients, half of them are Medicare Part D. They are patients who make less than 500 percent of poverty, so they make less than $128,000 per year for a family of four. Those patients we can provide free drug for. Anybody above that, we cannot. It is considered an inducement. And when you look at the copay for a drug like Humira, commercial patients, Medicaid patients, the low-income subsidy patients in Medicare, pay less than $100 per year of copay for Humira. A standard Part D patient pays $5,500. They make $26,000, so they cannot afford it. Senator Bennet. I apologize. I know I am out of time. Thank you. The Chairman. Senator Whitehouse? Senator Bennet. Could I, Sheldon, just make one point, which is, I think what we ought to be doing is figuring out how people do not have to cut their prescription drugs in half, and that would be a worthy goal for this committee and the people on this panel. The Chairman. Senator Whitehouse? Senator Whitehouse. I would like to ask about a particular segment of the pharmaceutical market. Chairman Grassley opened his remarks by talking about patients taking a drug that has no competition as being a cause for concern. Mr. Frazier, your testimony included the statement that price gouging by those who jack up the prices of off-patent drugs that have no competition is a problem. Let me ask if there is anyone on this panel who disagrees, who disagrees that there are de facto off-patent monopolies now in the pharmaceutical market? Does anybody disagree with that as a fact? Mr. Frazier. I do not disagree. Senator Whitehouse. In fact it is true. Mr. Frazier. There are. Senator Whitehouse. There are. Mr. Frazier. That is what I was saying. Senator Whitehouse. And indeed, is it also not true that sometimes these off-patent monopolies are used to impose monopoly pricing? Mr. Frazier. It is true, and I think the most egregious examples that we have seen recently have been exactly in that situation. Senator Whitehouse. Does anybody disagree with that? Everybody agrees. Now are there, among those entities that are in that category with off-patent monopolies that are extracting monopoly pricing by virtue of that, entrants who are not even really in the pharmaceutical industry? Mr. Frazier. Absolutely there are. Senator Whitehouse. They invest nothing in R&D. Mr. Frazier. Exactly. Senator Whitehouse. They do not even come from the pharmaceutical industry. Mr. Frazier. Yes. Senator Whitehouse. They are more or less corporate raiders who have bought something in order to jack up prices and take advantage of monopoly rents. Correct? Mr. Frazier. There are many people like that. Senator Whitehouse. There are many people like that. Does anybody disagree that that is a feature right now within the pharmaceutical market? Everybody agrees? Dr. Bourla. And I would add also, Senator, that they are not allowed to be part of the Pharma Association. Senator Whitehouse. So here is the problem: it is not difficult, in my view as a lawyer of many years and a prosecutor of many years, to prove the existence of a monopoly. We have been proving the existence of de facto monopolies in courtrooms and in regulatory proceedings for decades. So we can identify where these monopolies exist, even if you let all the ties go to the runner so that, wherever there is a real question, you throw that one out. There still would remain a significant population of entities where it is beyond dispute that they are pricing based on monopoly power. And as I look around, there is no place to address that. There is no organization in the Federal Government that is taking an interest in that, and it is the scandal, I view, of the pharmaceutical industry. And you guys take a hit for it. Here is the problem: when we try to do anything about that, the people you pay to lobby us here in Congress come out and say, ``Nope, we cannot do anything like that. That might look like price control.'' We are not interested in taking any look at this monopoly problem in your industry. I should not even say it is in your industry, because I think a lot of these people are raiders into your industry who are not really part of your industry. They do not really develop drugs. I see a lot of head-nodding here. So help us solve at least that problem. You know, there are lots of other problems that we are going to have to look through with your pricing. Help us solve at least that problem. Turn off your lawyers and your lobbyists as antagonists when we try to solve that problem. Mr. Frazier. We will. Senator---- Senator Whitehouse. In fact, switch them on and say, let us figure out how we deal with these modern monopolists who are not even really in the pharmaceutical industry. Mr. Frazier. I could not agree more. These people are at best tone-deaf, at worse abusive. I would also point out that there are companies here--I know, for example, my company. There is a very important cancer drug called TICE BCG. It was an invention of Merck. It has been off-patent for many many years. It is an incredibly essential drug for bladder cancer patients. A number of companies that were making it went out of the business. And so now we have had to double supply. Over the last nearly 12 years the cost of that drug has increased by $16. That is not how we make money at Merck. We make money at Merck by inventing new drugs that did not exist before. It is those people, I think, that contributed to the villainizing of an industry. The public cannot distinguish those people from the research-based companies. Senator Whitehouse. You all say that here. There is a lot of head-nodding here. There is a lot of agreement here. When your lobbyists come, everybody is in and they are not going to let anybody lose in all of this. We have to at least cut off these people. Mr. Frazier. Thank you for telling me that, because I never knew that our lobbyists were opposed to that. Senator Whitehouse. We have no support for working against these monopoly raiders. Dr. Brandicourt. Well, Senators, the message is very clear. And we are going to take that very seriously as a task. The Chairman. Senator Brown came back. So you will go ahead of the Senator from Nevada. Go ahead. Senator Brown. Thank you, Mr. Chairman. Thank you for doing this hearing. Thank you all for joining us. I want to thank Senator Hassan for her questions on opioids. Eleven people a day die in my State from opioid addiction, and there is a responsibility shared more widely than we sometimes say. I so appreciated Chairman Grassley's ``yes'' or ``no'' questions, and I appreciated the seven of you going along with his ``yes'' or ``no.'' And I would like to ask a series of ``yes'' or ``no'' questions, and please keep it to ``yes'' or ``no.'' They really are ``yes'' or ``no'' questions. Mr. Gonzales, let's start with you. Is it true that the pharmaceutical industry benefits from U.S. taxpayer-funded research? ``Yes'' or ``no''? Mr. Gonzalez. It is, yes. Senator Brown. Across, each of you. Mr. Soriot. Yes. Dr. Caforio. Yes. Ms. Taubert. Yes. Mr. Frazier. Yes. Dr. Bourla. Yes. Dr. Brandicourt. Yes. Senator Brown. Okay. Thank you. Is it true that no other nation invests more taxpayer dollars in basic research that directly and indirectly benefits the industry? Mr. Gonzalez. Yes. Mr. Soriot. Yes. Dr. Caforio. Yes. Ms. Taubert. Yes. Mr. Frazier. Yes. Dr. Bourla. I am not sure I understood the question. Senator Brown. Is it true that no other nation on earth invests more taxpayer dollars in basic research? Dr. Bourla. Yes. Dr. Brandicourt. Is it proportional to GDP, Senator? Senator Brown. I am not asking that, but that is close enough. Thank you. Is it true that the U.S. Government allows drug companies the longest period of exclusivity on biologics? Mr. Gonzalez? Mr. Gonzalez. I believe that is true. Mr. Soriot. I believe that is true. Dr. Caforio. I believe that is true. Ms. Taubert. Yes. Mr. Frazier. Yes. Dr. Bourla. Yes. Dr. Brandicourt. Yes. Senator Brown. We know Medicare limits prices with doctors and hospitals. Is it true that Medicare cannot negotiate to lower prices with drug companies? Mr. Gonzalez. That is true directly. Mr. Soriot. Yes. Dr. Caforio. Yes. Ms. Taubert. Yes; other agents work on their behalf to negotiate, but they do not negotiate directly. Mr. Frazier. Yes, they cannot negotiate directly. Dr. Bourla. Yes. Dr. Brandicourt. Yes. Senator Brown. Thank you. Is it true U.S. taxpayers subsidize pharmaceutical advertising and marketing activities through the tax code's business expense deduction? Mr. Gonzalez? Mr. Gonzalez. Yes. Mr. Soriot. Yes. Dr. Caforio. Yes. Ms. Taubert. Yes. Mr. Frazier. Yes, no different from any other advertising, but yes. Dr. Bourla. Yes. Dr. Brandicourt. Yes. Senator Brown. Thank you. We note the United States is the world's largest market for pharmaceuticals. Is it true that we pay the highest--in the overwhelming number of cases, is it true that we pay the highest drug prices in the world? Mr. Gonzalez? Mr. Gonzalez. The average government price would--that would not be the case. Senator Brown. No, that we as Americans individually pay the highest drug prices in the world? Mr. Gonzalez. As an average, that would be true. Mr. Soriot. I am not sure that it would be true, Senator, because the generic prices are some of the lowest in the world, and government prices, for many of our drugs even before patent expiry, are sometimes as low as Europe or lower. So on average, probably it is true, but there are many many different kinds of---- Senator Brown. I know there are exceptions. I am looking for an average. Dr. Caforio? Dr. Caforio. Yes, on average I would say. Senator Brown. Ms. Taubert? Ms. Taubert. I would say that the list prices are higher, but the net price in the United States is more comparable to much of the pricing outside the U.S. Senator Brown. Mr. Frazier? Mr. Frazier. Yes, outside Medicaid and other things, yes. Senator Brown. Okay. Dr. Bourla. Nine out of 10 products in the U.S. are generics. So the pricing of the generic products is much lower in the U.S. than other countries. Senator Brown. Yes, but generics---- Dr. Bourla. But you are right about branded---- Senator Brown. Do not confuse generic numbers of drugs sold with cost in the aggregate? Your answer? Dr. Bourla. But nine out of 10, I am telling you--you are right that in the innovation, the prices outside the U.S. in many cases are much higher. Dr. Brandicourt. So I would agree with that: patented drugs, yes, generics, no. Senator Brown. Okay. Thank you. Last question. Is it true that drug manufacturers set the--what Ms. Taubert talked about--list prices? Is it true that you, the drug manufacturers, set those list prices? Mr. Gonzalez. That is correct. Mr. Soriot. That is correct, but of course, there is a negotiation that takes place with PBMs and insurers about the price and the rebate level. Senator Brown. Dr. Caforio? Dr. Caforio. It is true for list price, but the delta between list and net price is the highest in the U.S. Senator Brown. Ms. Taubert? Ms. Taubert. Correct. Yes, we set the list price. Senator Brown. Mr. Frazier? Mr. Frazier. Yes, we set list price. Senator Brown. Dr. Bourla? Dr. Bourla. Actually, I would not agree that we set the list price. It is the result of a major negotiation. And I have to say that the problem in the U.S. health-care system it is that everything is geared around list price, a lot of incentives, which creates a hydraulic effect for the list prices to go down. I would be very happy to have much less list prices and the same net. Senator Brown. Dr. Brandicourt? Dr. Brandicourt. Ultimately, we set the listing price. Senator Brown. Okay. Thank you. So taxpayers subsidize your research, subsidize your marketing, and you continue to raise drug list prices on them. The median income of a person on Medicare is $26,000 a year, while the average annual cost for a single specialty medication was more than $52,000 in 2015. Americans cannot afford to pay for prescription drugs that cost more money than they make in a year. We cannot continue to give big pharma the blank check that you have had to pay for high-priced prescription drugs. But I guess it is not surprising that big drug companies take all the taxpayer money they can. What is so troubling is that this Congress continues, because of the lobbyists that Senator Whitehouse talked about and other pressures, that this Congress continues to allow you to do so. Thank you for answers. The Chairman. The Senator from Nevada. Senator Cortez Masto. Thank you for being here. Thank you, Mr. Chairman and Ranking Member, for this important hearing, one of four. Let me follow up on Senator Brown's line of questioning. Do any of you invest more in R&D than you spend on marketing and administration? If we could start ``yes'' or ``no'' to the right here. Dr. Brandicourt. No. Dr. Bourla. No. Mr. Frazier. Spend more on R&D versus marketing? Senator Cortez Masto. More in R&D than you spend on marketing and administration. Do you invest more in R&D than you do on marketing? Mr. Frazier. On marketing, but not if you include general administration, facilities, and all of that stuff. But yes, more than marketing. Senator Cortez Masto. Okay. Dr. Bourla. I would correct my answer also if it is only marketing. Yes, we spend more on R&D. Senator Cortez Masto. Let us just do marketing. Dr. Brandicourt [indicating agreement with Dr. Bourla]. Ms. Taubert. Yes, we spend 86 percent more on R&D than we do on sales and marketing. Senator Cortez Masto. Okay. Dr. Caforio. Yes, we do more on R&D. Mr. Soriot. Same, more than marketing, but excluding administrative costs. Mr. Gonzalez. Significantly more in R&D than sales and marketing. Senator Cortez Masto. But if you included administration with the marketing, that would be the reverse. Is that correct? Mr. Gonzalez. That is correct. Senator Cortez Masto. Yes from the rest of you? Mr. Frazier. It is about tied at Merck. Senator Cortez Masto. Okay. So let me just ask this question. Apart from New Zealand, nowhere else in the world will you see drug ads on television-- and I have asked this question for some of you. My understanding is--the answer that I have been given is that you maintain that television ads are a critical public health tool that helps patients identify their symptoms and seek treatment. Would you all agree with that? Is that a ``yes''? ``No''? Why do we have television ads when it---- Dr. Brandicourt. Yes, you are right. Senator Cortez Masto. Is that why? Is that a ``yes''? Dr. Brandicourt. Yes. Dr. Bourla. Yes. Mr. Frazier. Yes. Ms. Taubert. Yes. Dr. Caforio. Yes. Mr. Soriot. Yes. Mr. Gonzalez. Yes. Senator Cortez Masto. Okay. So if you maintain that television ads are a critical public health tool, then how can that be if our health outcomes are not significantly better than in those countries where it is outlawed? Dr. Bourla. Thank you, and you are raising a very good point. I think that the health-care outcomes and life expectancy-- there are a lot of factors that influence them. For example, exercise, diet, lifestyle, and I feel that our Nation needs to improve a lot in many of these cases. But I can assure you, Senator, that if you get cancer or another serious disease, you want to be treated in this country. Senator Cortez Masto. Okay. Dr. Bourla. There is no comparison. Senator Cortez Masto. All right. So let me jump back then to this discussion on authorized generics. And I am trying to understand this, I think, along with all of my colleagues, to address how we reduce the cost and get the drugs in the hands of the people who need them--where the R&D came in, where they were created--for individuals who actually need the drugs. I want to ask about the concept of authorized generics. Those, as you know, are the drugs that are identical to the brand, manufactured by the brand, but marketed without the brand on its label. Yet the companies, my understanding is, keep selling the higher-cost brand drug to consumers who, according to press reports, do not realize that the same product from the same company is available at a better price. All of you manufacture authorized generics to maintain your market share once your patent expires. Is that true? Dr. Brandicourt. No. Senator Cortez Masto. That is not true? Dr. Bourla. We do have authorized generics. Dr. Brandicourt. We do have authorized generics, but do not do it with the goal that you just highlighted. Senator Cortez Masto. So you do have authorized generics? Do all of you have authorized generics? Mr. Frazier. For some brands. Senator Cortez Masto. Okay. Ms. Taubert. Very selectively. Dr. Caforio. Very selectively. Mr. Soriot. We do not. Senator Cortez Masto. You do not? Mr. Gonzalez. I do not believe we do. Senator Cortez Masto. You do not have authorized generics? So for those of you who have authorized generics, explain to me, if you do have those, why do you continue selling the brand? Mr. Frazier. Okay, so in our case when we have had authorized generics, we have allowed a third-party to bring a generic product to market. The issue that you are really getting to, again, is the issue that Senator Cassidy talked about, which is transparency. At the end of the day, if patients really understood what their options were, they would not make these choices. But we have an opaque system, which is something that I think we have to change. We have to empower patients to be able to choose the cheapest medication. And Merck strongly supports generics. What I said in my introduction is, we will never use coupons when there is a generic. Senator Cortez Masto. What are you doing to empower the patients? What are you doing to empower the patients to understand that the generics are out there? Mr. Frazier. It is very hard. We do not connect with the patients in all those situations. That is why there is legislation saying, for example, that pharmacists must tell patients at the counter what the cheapest alternative is for them at the counter. We do not---- Senator Cortez Masto. So you rely on others to tell---- Mr. Frazier. Yes. We do not meet them at the counter, Senator. Senator Cortez Masto. Okay. Let me ask one final question, because I am running out of time here. I want to get a sense from all of you what types of policies you could support. I have heard some of those, but let me ask you this. Democrats have proposed to require manufacturers to submit advanced justification for price hikes that outpace inflation and make that information public. Given that many of you have already committed to tapering price hikes, is this something you could support, ``yes'' or ``no''? Dr. Brandicourt. We can support such legislation, yes. Dr. Bourla. Yes. Senator Cortez Masto. Thank you. Dr. Caforio. Yes. Ms. Taubert. We are very supportive of increased pricing transparency. Advance notification can cause problems in the supply chain and could cause outages for certain States. So we are very supportive of the notion of transparency. Advance notification can be problematic. Senator Cortez Masto. Okay. Dr. Caforio. We disclose our price increases. Senator Cortez Masto. Okay. Mr. Soriot. We support it. Mr. Gonzalez. We support it, but we would like to see consistency. As you probably know, California has that right now, but if we had a consistent standard that we operated with, that would certainly be helpful. Senator Cortez Masto. Thank you. Thank you very much. The Chairman. Senator Daines? Senator Daines. It is very clear from what is going on today that there are ultimately not any silver bullets to cure the high cost of prescription drugs. I am pleased that we can have this discussion. My hope is that we can truly find some ways to incentivize the system here to deliver a lower price, ultimately, for the consumer as well as incentivizing innovation. As manufacturers, you are responsible for setting this list price, this ethereal list price. But the more I hear what is going on here today, I am convinced we probably should call this the asking price. I am sure ``list price'' is a bit of a misnomer, because after hearing all about coupons, rebates, discounts, the pricing volatility--yes, I spent 13 years at Procter and Gamble, and once upon a time we drove a business with a lot of coupons, with rebates, pricing incentives. It was a very elastic pricing model. Oftentimes, we had a high-margin business. There is elasticity in the pricing, and you are an example of that. I spent 12 years in the cloud computing business after that. The margins were even higher. We saw great volatility in pricing and elasticity in pricing. We eventually, years ago of course, went to the everyday low price, EDLP, model. It, again, may or may not apply to Pharma. But it was just trying to take out all of that in between the manufacturer and the consumer nonsense that was going on, that was lacking transparency. And ultimately, I think the consumer was not winning in that equation, because the prices--they were not seeing really the true everyday low price. There are a lot of perverse incentives in the system today, as best I can tell. So my question is, who pays list price? Dr. Brandicourt. Unfortunately, the patient at the end, at the pharmacy counter, is probably one of the few paying the list price. Mr. Frazier. There is a small percentage of people who have no insurance who could actually be charged the list price. Senator Daines. So the people who can afford it the least, arguably, are paying list price. Mr. Frazier. Senator, that to me is what I meant by saying, in some ways the reimbursement system here is regressive. The people who can least afford it are paying the most. Senator Daines. Do you think that that is a good system? Mr. Frazier. I do not. I can tell you that is, to me, the biggest problem that we have as a country, that we now have a system where the poorest and the sickest are subsidizing others. Senator Daines. Okay. So with insurance companies that now own the PBMs and the supply chain from the time you list the price until the consumer eventually gets it, is it fair to say the list price is really a starting point for, then, a negotiation? Mr. Frazier. Yes. Senator Daines. Does anybody disagree with that premise? Ms. Taubert. No. Senator Daines. So what are some of the incentives? And maybe we will start with Mr. Frazier. What are the incentives that contribute to high list prices that are being paid by those who can afford them least? Mr. Frazier. The real answer, Senator, is, if you went back a few years ago when we negotiated to get our drugs on formulary, our goal was to have the lowest copay for patients. Today the goal is to pay into the supply chain the biggest rebate. And so that actually puts the patient at a disadvantage, since they are the only ones who are paying a portion of the list price. The list price is actually working against the patient. Senator Daines. So why do we have a system today where you all are setting--I will just say very very high list prices, which is our starting point for negotiation? Why? Dr. Brandicourt. Senator, we are trying to get formulary position with those high list prices, high rebates. It is a preferred position. Unfortunately, the preferred position does not automatically ensure affordability at the end of the day. Mr. Frazier. And, Senator, if you bring a product to the market with a low list price in this system, you get punished financially and you get no uptake, because everyone in the supply chain makes money as a result of a higher list price. Senator Daines. Chairman Grassley, if I could just ask a follow-up question here. And that is, the GAO report said that generics might fall 20 percent for each new generic entrant into the market. I appreciate the chairman's efforts here with the CREATES Act. It is going to crack down on some of these bad actors who block or delay competing generic drugs from entering the market. I have co-sponsored the bill, and I think that will help us provide better access to low-cost generics. Here is my question: has your company ever withheld samples from generic manufacturers? Dr. Brandicourt. No. Dr. Bourla. No. Mr. Frazier. No. Ms. Taubert. No. Dr. Caforio. No. Mr. Soriot. No. Mr. Gonzalez. No. Senator Daines. Right. Do you believe the CREATES Act would be a positive step forward, ensuring generics enter the market in a timely fashion? I would love to poll the team here. Mr. Frazier. I said in my testimony, legislation like the CREATES Act would be positive in that regard. Dr. Bourla. Yes. Dr. Brandicourt. Yes. Dr. Caforio. Yes. Mr. Soriot. Yes. Mr. Gonzalez. We are supportive. Ms. Taubert. We are supportive of efforts to make sure that there are no abuses of that sample system. Senator Daines. All right; I am out a time now. Thank you. The Chairman. Senator Young? Senator Young. Thank you, Mr. Chairman. I want to move to the issue of Medicaid best price. In the Trump administration's blueprint, they suggest that because drug manufacturers have to give Medicaid the best price drugs, there is no incentive to offer deeper discounts to other payers, both government and commercial, than what is already offered under the Medicaid drug rebate program. So first of all, I would ask each of you, is the Trump administration's assessment accurate? Mr. Gonzalez. In concept, I would say I understand the concept. In other words, if you have best price, you obviously have to be conscious of where that price is going, because it is going to be compared against that. I would tell you in practice, because of the negotiation that occurs in the formula around Medicaid, I do not believe that that is actually, today, resulting in higher prices in the Medicare program. Senator Young. You have anticipated my follow-up question. So I appreciate that. So the best price requirement does not encourage manufacturers to increase initial prices? You have thoughts on that? Mr. Gonzalez. I would say it does not necessarily encourage you to set a higher list price. I think what happens with list price is this negotiation you have heard of, going forward, where you are looking for a certain amount of impact to fall through, but the rebates and the other aspects of the value chain in between absorb a large chunk of that, which drives list prices, increases up higher. Senator Young. Okay. Others? Mr. Frazier. I think where best price really is an issue is, again, it is a barrier to the kind of value-based pricing that we want to have within the marketplace, where if, for example, a drug did not work, you might reimburse that payer for that unit, where that becomes a problem for value-based pricing. Dr. Brandicourt. Another example, Senator, is when you want to put on the market a second NDC, like we did recently where it had a much lower list price, then the best price potentially becomes a problem because it is calculated with the other version, the higher list price version, which has stayed on the market. So that is something to pay attention to. Senator Young. What changes, if any--if I could pivot a bit--would you suggest making to the program? Dr. Caforio. Senator, I believe that flexibility with value-based arrangements is really important, because I think we have all expressed a strong support for a system where we are paid based on the clinical results that our medicines produce in patients and having greater flexibility to do that. It would be very, very important. It would be very valuable for patients. It would reduce health-care costs overall. Senator Young. General agreement? Ms. Taubert. Yes, we agree. Mr. Frazier. Yes. Senator Young. Okay. So would you be willing to work with the administration on a different model, one you regard as more optimal? Ms. Taubert. Absolutely. Senator Young. Very good. Thank you. With respect to reducing drug prices and the subsidies that U.S. payers provide with respect to research and development to much of the rest of the wealthy world, the President and the administration have gone so far as to issue proposals, like the international pricing index, which we all are familiar with, to bring down prescription drug prices. So with the increased scrutiny of the industry and of the drug supply chain as a whole in the U.S., have any of your companies re-evaluated your business strategy in foreign countries? Mr. Frazier. That is a common question that we get asked. And the answer to that question is, we do everything in our power to ensure that there is less freeloading by governments outside the United States. But the reality of the world is, the greatest opportunity we have is to walk away. And that is really challenging when you have the kinds of essential medicines that make a big difference to people's lives. And frankly, they know that. They know that they can establish a price, and that ultimately what we have is an option to walk away, leaving patients behind. I would also make the point that has been made several times here, that in the course of negotiating for reimbursement, often those countries take a very deliberate approach, such that these medicines are available many years later than they are here. So they not only negotiate on a low price, but they actually provide very few of these medicines early on to their populations. If you look at, for example, lung cancer, where in this country now, there is data showing that certain medicines can reduce the risk of death by 50 percent in newly diagnosed lung cancer patients, compare that to the UK, where people die regularly of lung cancer because they do not have these medicines. Mr. Soriot. Senator, I think it is important to keep in mind that all these investments, number one, create a lot of very good jobs in the U.S. and economic value that really benefits the country. And second, they allow patients to get access to important new medicines much, much, much earlier than in Europe, for instance, sometimes 3, 4 years before. And I share Mr. Frazier's comment here. I have many examples that I could share where medicines that save lives are available here. We are still waiting in Europe. The Chairman. Just three more questions. One from--if some of you want to answer yet, I did not mean to interrupt you. Go ahead. Mr. Gonzalez. The only thing I would add is, if we could develop a model where, as in the early days of HIV when countries ultimately shared the burden, knowing that you would have to provide HIV treatments at a very low cost in certain countries, there was a tiered pricing system that came through where, yes, the U.S. paid the highest price, but the Europeans paid a fairly significant price for very important specialty medicines. If we could negotiate through trade or other mechanisms, we would be able to get a more balanced sharing of the investment that is made, not keeping all of that burden on the U.S., because the U.S. does bear the bulk of the burden of innovation in our business. That is absolutely true. Senator Young. So that is a really interesting idea. If you or your team are aware of any academic paper you might bring to my attention---- The Chairman. Okay. That is the end. Senator Young. Thank you, Mr. Chairman. The Chairman. Yes. Now we have three questions, one from Senator Wyden, then Senator Cassidy, then me. And then that will be it. Senator Wyden. Thank you very much, Mr. Chairman. This is going to be one question and then a very brief closer. And the question is for you, Mr. Gonzalez. I have the company's proxy statement here. And financial disclosures show that you were paid $22.6 million in 2017, and that included a $4.3-million bonus. That is what I want to look at. On page 37 in this proxy statement, it says your bonus was tied to the financial performance of Humira. And it seems that was the case in 2015 and 2016. That strikes me as problematic, since AbbVie reported that the higher prices in the U.S. were responsible for increasing sales of Humira. Would you make a smaller bonus if you dropped the price of Humira? Mr. Gonzalez. Humira was one element of a set of financial factors that were evaluated as part of my compensation. It is obviously a very significant product for us. So it is clear that it would be a part of that evaluation. Senator Wyden. I would like that in writing. It looks to me like you would be making a smaller bonus if you dropped the price of Humira. I would like that in writing within 10 days. My last point--Mr. Chairman, I appreciate being able to do this for a closer--is that I have heard a lot of happy talk this morning, things like, well, if you get rid of rebates, drug prices are going to go down. But what people are taking away from this hearing is--I have seen it said and reported-- well, no firm commitments have been made to lower list prices. So I am just going to tell you what I would like in writing is, I would like an answer in writing to the question, if rebates go away, will you support a black letter law that requires that you reduce list prices by the amount of the rebate? I am going to get that to you right away. I would like an answer within 10 days, because that is right at the heart of this issue, and after the ``happy talk'' is over, that is what is really going to help people at pharmacy counters from sea to shining sea. Thank you, Mr. Chairman. The Chairman. Senator Cassidy? Senator Cassidy. Thank you, Mr. Chairman. Thank you, again. This has been incredibly provocative. And if there is a tension here, the tension is, how do we support innovation, but at the same time make it that the patient can afford that innovation? Mr. Frazier, you may have guessed that--it seems like we have a mirror image, in my mind. Either the plans impose a price or the government imposes a price. But either way, the side having it imposed upon them is not very wild about that. And you just mentioned to Todd Young that you can walk away. If France offers you too low a price, you just walk away from France. The UK does not have a deal right now. But in some areas, Medicare cannot walk away. So it is back to that mirror image. And you started to say something and I was out of time. But my question is, in the six protected classes--and if there is a new drug, like Sovaldi was at the beginning, right now the commercials can walk away, the commercials can delay, but Medicare cannot. So help me resolve this. How do we give the patient, the taxpayer, the same sort of tools that--and by the way, CBO says unless you can walk away, negotiations will not lower prices. Mr. Frazier. So my point was, for all practical purposes, we cannot walk away from our European colleagues, even though they give us low prices, because we think it would be immoral to leave those patients---- Senator Cassidy. Now some of your colleagues have, because there are drugs not yet available in the UK. Mr. Frazier. Well, the problem with the UK is that they delay. Just like they can set the price, they delay when they put the drug on the market. It is the UK's delay, it is not our delay. So I want to clarify that point. But coming back to your six protected classes, those protected classes are there because many, many sick vulnerable people need medicines in those classes. And we believe that there are ways of lowering the prices, stimulating innovation, without violating the compact that was around those six protected classes, because patients are particularly needing those medicines. Senator Cassidy. Well, we will have to leave it there, but I am not sure that is--you know, that seems almost status quo. And status quo is kind of not working. But again, thank you all very much, and I thank you again for your innovation. Dr. Bourla. I would add, Senator, I believe the administration should try, through trade agreements, to protect the American innovation, because by and large the pharmaceutical innovation is happening in this country. And right now, I think rightly, these price control mechanisms are for multiple well-developed countries. It is in reality free- riding on American innovation. Senator Cassidy. Okay. Well, thank you. The Chairman. My last question is very general, but I would like to know if there are any policies affecting Medicaid or Medicare that are in your control to change? In other words, from the company level, is there anything in your control that you could change on Medicare or Medicaid? I will start with you on my right here. Dr. Brandicourt. I do not think we can change directly any policy, Senator, on Medicare or Medicaid. We can talk about different solutions, but I do not think we can change. We have no power to change. The Chairman. But if you lowered your list price, it would help. That is one thing you could do. Dr. Brandicourt. If we were able to lower our list price, that would certainly help, again, the patient at the end, at the pharmacy, to have a copay which they could afford. However, we could not do that independently of a major reform because we would lose formulary placement if we were doing that in isolation, and especially in very competitive areas where you do have, you know, brands and generics. And again, I am referring to the insulin market, which has become extremely, extremely competitive. That would not work. The Chairman. Do you have anything? Dr. Bourla. Mr. Chairman, I think the most impactful thing I can do right now it is to make the pledge that, as leader of this company, Pfizer, I would be taking very seriously the responsible pricing of our products. This is something that we have already started. Pricing at Pfizer in the past was growing in the mid-single digits, even more in some cases. This is not something that we continued doing. Pricing at Pfizer went down last year, went down this year. And when I spoke to our investors, not to the Senate, to our investors, I made it very clear that pricing will not be a growth driver for this company now or in the years to come. Why do I think this is the most important? Because I think the tone is set from the top. The Chairman. Mr. Frazier? Mr. Frazier. Senator, I understand the dissatisfaction with our industry. I understand why patients are frustrated, because they need these medicines and they cannot afford them. I would pledge to do everything that we could, but I would urge you to recognize that the system itself is complex, and it is interdependent. And no one company can unilaterally lower list prices without running into financial and operating disadvantages that make it impossible to do that. But if we bring all the parties together around the table with the goal of doing what is best for the patient, I think we can come up with a system that works for all Americans. Thank you for giving us the time today. The Chairman. I did not mean to--for the rest of you, before you answer, I did not mean to say list price. I just said, well, that is kind of obvious. Yes, I did not want to concentrate just on that. Ms. Taubert? Ms. Taubert. We really want to be a part of the solution, and we want patients to be able to access and pay for the medicines that they so desperately need. So we do strongly advocate for rebate reforms that would allow us to lower our list prices that would then end up helping patients get access. The Chairman. Dr. Caforio? Dr. Caforio. Mr. Chairman, I would echo. Our perspective is that it starts with a very responsible and thoughtful approach to pricing and price increases. That is what Bristol-Myers Squibb does. The second point that I would like to make is that, today we have discussed a number of very concrete policies, from addressing the issue of rebates to value-based pricing to supporting the development of a generic and biosimilar market. And you have my commitment that our company is looking forward to working with this committee and the administration to make sure that many of those policies can be enacted, because they would make a very big difference for our patients. The Chairman. Mr. Soriot? Mr. Soriot. Senator, we actually cannot influence policy. What we can do is, indeed, apply reasonable pricing and also continue pushing for value-based pricing. But I would like to make a general comment, which is that hopefully--you know, hopefully my colleagues will share this. This view is that I really do not think we are blaming anybody in the system. In his introduction, Senator Wyden thought that we were placing the blame on PBMs and others. I really do not think we are doing this. I think what it is is that we are in a system that used to be fit for purpose and really drove enormous savings over the last few years but is no longer fit for purpose. And it is one of those situations where nobody in the system can do anything, can fix it by themselves. The government has to step up and change the rules, and those rebates have to go. The Chairman. Mr. Gonzalez? Mr. Gonzalez. I think I would agree with many of the points that were already raised. We as an industry have to continue to do everything we can to be responsible about pricing in both how we set pricing and price increases over time. I think we have seen a positive trend in that area. But ultimately, the final fixes here to realign the system appropriately would require legislative-type changes. The only other thing I would say is, as I mentioned a moment ago, we are absolutely committed that no patient goes without medicine of ours that they need. And we have an extensive patient assistance program, but we are talking about how we more broadly ensure all patients understand they can get that support from us if they cannot afford their medicines. The Chairman. I want to inform all members of the committee that I will set a deadline of March 12th if you have questions you want to submit to the panel for answers in writing. And then for you folks, after you get those questions, I hope you can get back to us very quickly. And so, all of the people besides the witnesses who have attended either here or off-site for this hearing, I thank you for your interest in this issue. And I want to once again thank our witnesses for being here today and sharing your knowledge and expertise. And I indicated that this is the start of a dialogue I hope to have with you so that we can correct some of these things that have been pointed out at this committee meeting that we think need to be corrected. Thank you all very much. Meeting adjourned. [Whereupon, at 1:25 p.m., the hearing was concluded.] A P P E N D I X Additional Material Submitted for the Record ---------- Prepared Statement of Albert Bourla, DVM, Ph.D., Chief Executive Officer, Pfizer Chairman Grassley, Ranking Member Wyden, and members of the committee, thank you for the opportunity to speak with you today. My name is Albert Bourla. I have been with Pfizer for 26 years, and just last month had the honor of becoming its chief executive officer. Today, I am pleased to take part in such an important policy discussion within the United States Senate. Pfizer shares an important goal with this committee: to ensure that America remains the leader when it comes to innovative medicines, and that our citizens have affordable access to these modern miracles when they need them. In that frightening moment when you hear that you or a loved one has been diagnosed with a serious disease, one question comes to mind: ``Is there a cure or treatment available?'' The answer can change your life. And happily, the answer to that question increasingly is ``yes.'' Breakthrough medicines are coming quickly across a wide range of conditions. Most of them are discovered here, by the American Biopharmaceutical Industry, which is the crown jewel of innovation. Let me share a few examples. In 2015, Pfizer launched a life-changing new treatment for metastatic breast cancer that can delay the progression of the disease two times longer than previous treatments. Thanks to our meningitis B vaccine, parents can send their teens to college confident in the knowledge that being vaccinated helps protect them in the event of an outbreak on campus. In 2018, we brought 4 new cancer treatments to the market to treat varying forms of breast cancer, lung cancer and leukemia. And we are currently working on a non-opioid alternative with the potential to address the serious unmet needs of the more than 27 million Americans living with osteoarthritis and the more than 33 million suffering chronic low back pain. But all of these breakthroughs won't do anyone any good if patients can't afford them. That's why at Pfizer we are so committed to our purpose: breakthroughs that change patients' lives. Pfizer's more than 90,000 colleagues around the world come to work every day focused not only on creating breakthrough medicines, but also on making sure those medicines get into the hands of the patients who need them. To create solutions that make medicines affordable for patients and our entire health-care system, I believe that all players in the industry must come together and play a part. Whether it's hospitals or providers, pharmacy benefit managers or insurance companies, or biopharmaceutical companies, we all have a role to play. The series of hearings being held by Congress can be a catalyst for this much- needed collaboration. There are two indisputable truths that make this the exact right moment for change: 1. Medicines alleviate human suffering and reduce overall system costs. 2. The horribly misaligned incentives within our health-care system often prevent medicines from getting into the hands of patients. Our health-care system is broken, and we need to fix it. The system needs to be simpler and more transparent. It needs to incentivize innovation while simultaneously ensuring access. Simply put, it needs to put patients--and their health--first. How will we know when the health-care system is fixed? When patients feel real relief at the pharmacy counter--the kind of relief that means cost will no longer be a determining factor in whether someone picks up, and adheres to, their prescription. Too often, Americans are forced to choose between buying a medication that will improve, extend or save their lives or paying their bills. Too often, they fill their prescriptions, but take less than the prescribed dose in an effort to save money. Too often, lower-cost, FDA-approved generic and biosimilar alternatives are not made available to patients who desperately need them. We must take bold actions to ensure these scenarios do not play out time and time again across America. Pfizer intends to be a productive participant in this policy making and has come to the table with solutions. As such, we would like to propose four ideas to drive meaningful reductions in costs for patients. passing all rebates to patients Today's current drug rebate system is good for two things: driving up both drug list prices and consumer out-of-pocket costs. In fact, in 2018, the average net price of Pfizer's medicines in the United States declined 1 percent. However, I am certain that patients using our medicines had a very different experience at the pharmacy counter since their costs in the current system are more closely related to the list price than the net price. This is impactful when patients pay a coinsurance or are in the deductible phase of their benefits coverage. In these instances, patients are being asked to pay an average of 10 percent to 20 percent or more out of their own pockets for many Pfizer products. There are two reasons for this disconnect: changes in benefit designs are pushing more and more of the medicines' cost to the pockets of the patients, and none of the close to $12 billion of rebates that Pfizer paid in 2018 found their way to American patients. As long as rebates serve as profit drivers, we will continue to see a major disconnect between list prices and prices people pay at the counter. Pfizer supports reforms that would create a system in which transparent, up-front discounts benefit patients at the pharmacy counter, rather than a system driven by rebates that are swallowed up by companies in the supply chain. The way to alleviate sticker shock at the pharmacy counter is by changing the incentives in the supply chain so that more of the $150 billion in negotiated rebates and discounts actually reach patients. This can be accomplished by applying the discounts paid by the pharmaceutical manufacturer to the price actually paid by patients at the pharmacy. In 2019, Pfizer expects to pay billions in rebates to ensure patients with pharmacy benefits coverage in Medicare Part D and patients in commercial plans have access to our medicines. If the proposed rule to share rebates with consumers at the point of sale is finalized, we estimate that seniors taking Pfizer medicines could save $270 on average per year, and up to $574 per year for certain Pfizer medicines, through lower cost sharing--and that would outweigh any premium increases. Research also shows that sharing discounts at the pharmacy counter could reduce total health-care spending, and that reductions in overall out-of-pocket costs would outweigh any premium increases. We realize that the transition away from rebates toward a point-of- sale discount model will result in a lowering of our net prices. Despite this potential negative financial impact, we support efforts to eliminate rebates because we believe the new model will be good for patients. Importantly, we believe any reform should apply to all market segments as this will also lead to further reduction in list prices. A bifurcated market in which we eliminate rebates in government programs but maintain rebates for commercial plans will make it difficult for manufacturers to reduce list prices because it applies to all markets. We will work with other leaders in the healthcare sector to advance these reforms, and we're committed to lowering list prices if the rebate rule applies to the commercial market. less value, less pay Pfizer supports the move to value-based health care and is prepared to stand behind the benefits that our medicines deliver to patients and to the United States health-care system. Medical science is advancing so rapidly that payment models simply haven't been able to keep up. That's why Pfizer is focusing not only on scientific innovation, but also on commercial innovations that will allow us to get breakthrough medicines into the hands of patients, while simultaneously holding all participants in the system--including Pfizer--accountable for the health outcomes they help produce. This will require a fundamental shift in the way we think about the value that medicines deliver and how all participants in the system are reimbursed with regard to that value. It will also require the evolution of insurance designs to advance value-based insurance plans that removebarriers to high-value treatments. Imagine a system in which hospitals are rewarded for keeping patients from being readmitted; where physicians get paid more to prevent disease than they do to simply treat it; and where companies like Pfizer get paid based on the number of strokes we prevent or the number of cancer patients who go into full remission, rather than the number of pills we sell. In such a system, if our medicines do not produce results, we would be paid less. And if they do produce results, we would be paid more. If done correctly, these arrangements--focused on the appropriate therapeutic areas--can align the interests of patients, health plans and biopharmaceutical companies around one shared goal: ensuring positive health outcomes for the patient. To make this a reality, we need Congress's help to remove the roadblocks in the current system for the good of patients. I understand several members of this committee are drafting a legislative effort to pave the way for broader adoption of outcomes-based arrangements, and we applaud these efforts. capping seniors' out-of-pocket medicine costs Patients are increasingly being required to take on a bigger share of their medicines' costs, and that is particularly true when it comes to innovative and expensive treatments. Today, patients are made to pay on average 14 percent of the cost of their medicines, but only 3 percent of the costs associated with hospital stays. This is forcing patients to forgo taking needed medications, to cut their pills in half, or to limit their doses in ways that are not medically prescribed. In fact, there is evidence that at least a quarter of new Medicare Part D prescriptions are abandoned at the pharmacy counter if beneficiaries are asked to pay $50 or more, which unfortunately is often the case. This number can exceed 50 percent for new prescriptions. This is bad not only for patients, but also for overall health-care system cost. Patients who do not take their medications often end up in the hospital, costing the health-care system much more. This needs to be fixed. Excessive cost-sharing is one of the greatest barriers to patient adherence and leads to more frequent discontinuation of therapy. While spending on medicines has been growing at a slower rate than in prior years, the number of patients with high deductible plans and high co- insurance are growing rapidly. Since 2009, enrollment in high deductible plans has grown 250 percent, and since 2010 the number of patients exposed to high specialty tiers has grown 60 percent. In fact, I've heard from several members of this committee that their constituents--or they themselves--have recently gone to the pharmacy counter only to be shocked by an excessively high co-pay. That's why the time is now to review cost-sharing burdens in the Medicare prescription drug program and to take steps to ensure seniors don't have to make the difficult decision of forgoing their needed prescription. We commit to working with the committee on meaningful policy solutions that remove the burdens seniors face in paying for their medicines, and we believe an important first step is capping the out- of-pocket costs seniors experience in the Medicare drug program. knocking down barriers to lower-cost biosimilars Medicines are the only segment of the health-care system with a built-in cost containment mechanism. When a medicine's patent expires, lower-cost generics are made available, often at just 5 percent of the cost of the original branded product. This system is working well for generic drugs. In fact, nine out of 10 drugs sold in the U.S. today are lower-cost generics. However, the system is not yet working in the biologics space where the adoption of biosimilars is facing resistance. Establishing a robust biosimilars market can help to lower the overall health-care costs in the United States, and Pfizer is committed to bringing these more affordable treatment options to patients. That's why we must incentivize the use of biosimilars, which can be as much as 40 percent less expensive than the branded biologic for Medicare patients. Unfortunately, adverse incentives that favor higher-cost originator biologics are keeping biosimilars from reaching patients. In many cases, payers decline to include lower-cost biosimilars or generics in their formularies because they would risk losing the rebates they can get by covering higher-cost medicines. I can't think of a more concerning example of a broken U.S. healthcare system that is directly impacting the pocketbooks of Americans. We have also witnessed exclusionary contracting or misleading marketing practices that mischaracterize important elements of biosimilar criteria. This creates doubt and confusion among patients, and it must end. Interestingly, the rebate reform I referenced earlier would go a long way toward removing the perverse incentives that lead to such exclusionary contracts. At Pfizer, we believe there are several solutions that could help patients and providers share savings associated with biosimilars and reduce costs to the Medicare program. Let me touch on two: A Shared Savings Biosimilars Model: Congress could direct the CMS Innovation Center (CMMI) to test a biosimilar ``shared savings'' approach in which Medicare savings associated with prescribing a biosimilar, as compared to a reference biological, would be shared with providers. Reduced Patient Cost Sharing for Biosimilars: CMS could provide reduced or zero-dollar cost sharing for biosimilars for patients for a certain period. closing In 2018, we estimate \1\ that Pfizer vaccines protected more than 65 million babies and elderly patients; our medicines helped reduce the risk of heart attack or stroke for more than 48 million cardiovascular patients; and oncologists used our therapies to treat more than 1.2 million people battling cancer. --------------------------------------------------------------------------- \1\ Patient counts are estimates derived from multiple data sources. Overall more than 784 million people around the world used a Pfizer medicine or vaccine to improve their health and, in many cases, save --------------------------------------------------------------------------- their lives. These are staggering and humbling numbers. More important, they represent real people; real people who rely on our innovations. They also serve as a reminder that we--like our industry peers--are among the biggest contributors of good to humanity. This is why we come to work every day. It's why the researchers in our labs in California, Connecticut, Massachusetts and New York work day-in and day-out to perfect a formula. It's why our manufacturing colleagues in Georgia, Kansas, Michigan, Missouri, North Carolina, Ohio, Pennsylvania and Wisconsin--many of whom are represented by members of this committee--work to ensure the reliable supply and highest standards of quality of our products. And it's why we are here today to work with our peers, other participants in the healthcare system, and Congress to find ways to ensure the patients who need our medicines can access them so our industry's breakthroughs can continue to change patients' lives. ______ Questions Submitted for the Record to Albert Bourla, DVM, Ph.D. Questions Submitted by Hon. Chuck Grassley Question. At the hearing, you testified that Pfizer does not withhold samples from generic manufacturers in order to block generic versions of your drug from entering the market. You also expressed your support for the ``Creating and Restoring Equal Access to Equivalent Samples Act,'' also known as the CREATES Act. However, the FDA has a list on its website which identifies reference listed drug (RLD) access inquiries where brand manufacturers may have prevented generic companies from obtaining samples of products necessary to support FDA approval. Pfizer is on this FDA list. This would appear to contradict your testimony at the hearing that Pfizer has not withheld samples of their products to delay generic competition. Could you please explain in detail why Pfizer is on the FDA list? Could you please explain in detail the discrepancy between your testimony and the FDA list? Has Pfizer ever blocked access to samples? Answer. As a patient-focused company and leading manufacturer of innovative, generic, and biosimilar medicines, Pfizer supports innovation and a strong, competitive marketplace. Consistent with these values, Pfizer does not block generic manufacturers from purchasing our products, and it has never been our policy to do so. Generic manufacturers are treated the same as any other customer seeking to purchase our products. Pfizer is not aware of any current, unfulfilled requests from a generic manufacturer to purchase a Pfizer product. Generic manufacturers seeking to purchase Pfizer products should request the product from Pfizer's authorized distributors or, if the product is not available at a distributor, from Pfizer directly, the same as any other Pfizer customers. Pfizer's website includes a list of our authorized distributors, from which customers (including generic companies) may purchase most Pfizer products (see https://www. pfizer.com/products/medicine-distributors). For products that are not available via our authorized distributors and that are not in extreme drug shortage or unavailable due to a recall, customers can contact Pfizer's Customer Service center at 1-800-TRY-FIRST (1-800-879-3477) to purchase product directly from Pfizer. The telephone number for Pfizer's Customer Service center is also included on our website at https://www.pfizer.com/contact. Pfizer makes its products available for sale to appropriately licensed entities at Pfizer's listed price and on Pfizer's standard terms of sale. We do not have any agreements with authorized distributors that block the sale of Pfizer's products to generic manufacturers. Regarding the FDA List (the List), while Pfizer supports FDA's (the agency) goal of providing transparency, Pfizer is concerned that the List lacks certain key information and context and, as currently presented, may create the misleading impression that all products on the List are the result of bad faith attempts to block generic manufacturer access to samples. The appearance of a product on the FDA List means only that a generic manufacturer informed the agency at some point in time that it was having difficulty purchasing the listed product. FDA's own disclaimer states that the agency has not independently investigated or confirmed whether a generic manufacturer actually made a request to purchase product, and to whom.\1\ The FDA List also lacks several important pieces of information that would enable a New Drug Application (NDA) holder to investigate its appearance on the List. The List does not include: (1) which generic manufacturer made the request; (2) when and to whom the generic manufacturer made the request (e.g., to a wholesaler or directly to the NDA holder); (3) whether the generic manufacturer that made the inquiry was thereafter able to obtain product; and (4) any reason(s) why a generic manufacturer may not have been able to obtain product (e.g., a recall). Finally, Pfizer notes that FDA does not currently inform an NDA holder in real time when a generic manufacturer notifies the agency that it is having difficulty obtaining product. Had the agency informed Pfizer at the time it received the inquiries noted on the FDA List, Pfizer could have then undertaken its own efforts to resolve the issue. Pfizer communicated its concerns about the FDA List to the agency in May 2018. For your information we have included Pfizer's letter to FDA on this topic and the agency's response (see Exhibits 1 and 2 in the Appendix). --------------------------------------------------------------------------- \1\ (https://www.fda.gov/Drugs/DevelopmentApprovalProcess/ HowDrugsareDevelopedandAp proved/ApprovalApplications/AbbreviatedNewDrugApplicationANDAGenerics/ ucm607738.htm). There are three new drug applications owned by Pfizer on the FDA List: Embeda (NDA 022321), Tikosyn (NDA 020931) and Hemabate (NDA 017989). Embeda offers a good example of the List's shortcomings. Pfizer acquired King Pharmaceuticals (the previous NDA holder of Embeda) in March 2011, and two weeks later determined that Embeda needed to be recalled from the U.S. market due to stability issues. After diligently addressing the issues that led to the recall, Pfizer relaunched Embeda to the U.S. market in January 2015, and it is available for purchase via Pfizer's authorized distributors. However, one consequence of the recall was that Embeda was not available in the U.S. market for almost 4 years which may explain why a generic manufacturer had a problem obtaining it during those years. The FDA List does not specify when the generic manufacturer's inquiry regarding Embeda was made nor does the FDA List indicate that several generic applications for Embeda had been submitted to FDA in 2010 (which means that before the recall, several generic manufacturers were successfully able to purchase Embeda, conduct the necessary testing, and file Abbreviated New Drug Applications (ANDAs)). Pfizer has not identified any recent inquiries from generic manufacturers seeking to purchase --------------------------------------------------------------------------- Embeda that have not been fulfilled. The circumstances around Tikosyn also illustrate the List's shortcomings. Pfizer was able to identify a single inquiry made by a generic manufacturer directly to Pfizer to purchase Tikosyn in 2014. At that time, Tikosyn was subject to an FDA imposed Risk Evaluation and Mitigation Strategies (REMS) with Elements to Assure Safe Use (``ETASU'') that restricted distribution, so Pfizer responded by asking the manufacturer to obtain written confirmation from the FDA that Pfizer's provision of the product to the generic manufacturer would not be considered a violation of its REMS. The generic manufacturer did not contact Pfizer further, and Pfizer never received any written correspondence from the agency. FDA subsequently removed the REMS for Tikosyn in 2016, and multiple generic versions of Tikosyn are now approved, the first generic approval occurring in June 2016. This context is not reflected in FDA's List. Finally, with respect to Hemabate, this product was previously subject to certain restrictions on distribution (i.e., it was sold only to customers with medical and surgical intensive care centers) to ensure its safe and appropriate use. This distribution approach was established by the previous NDA holder (Pharmacia) and it continued following Pfizer's acquisition of Pharmacia in 2003. Pfizer discontinued this approach in early 2018 after determining that it was no longer necessary, and this product is now available through our authorized distributors. During the time when Hemabate was under restricted distribution, it was not available at Pfizer's authorized distributors, but had a generic manufacturer approached Pfizer's Customer Service center directly, we would have been able to address the inquiry. Pfizer's Customer Service was not able to identify any specific requests from a generic manufacturer to purchase Hemabate that have not been fulfilled. We hope that this information explains the apparent discrepancy between Mr. Bourla's testimony and the appearance of these Pfizer products on the FDA List, and demonstrates Pfizer's diligence on these issues and commitment to a competitive marketplace. Question. The Department of Health and Human Services' proposed rule, ``Fraud and Abuse; Removal of Safe Harbor Protection for Rebates Involving Prescription Pharmaceuticals and Creation of New Safe Harbor Protection for Certain Point-of-Sale Reductions in Price on Prescription Pharmaceuticals and Certain Pharmacy Benefit Manager Service Fees,'' envisions that drug manufacturers will offer up-front discounts rather than the back-end rebates that are now commonly provided. Some observers argue that a 1996 court case called into question whether manufacturers could offer up-front discounts, resulting in today's rebate-based system. I've heard differing opinions as to whether the issues related to the initial court case are still relevant. If the HHS proposed rule is finalized, can you assure the committee that your company will offer up-front discounts? If not, why? Answer. Yes, if finalized, price concessions negotiated with intermediaries, including Pharmacy Benefit Managers (PBMs) and plan sponsors, will be provided as discounts that will be applied at the point of sale. These discounts will lower patient out-of-pocket costs since the net price will be used to determine the cost to the patient when they are in the deductible, co-insurance, and coverage gap phases of their benefits. Question. Please describe how you expect your company to respond to the HHS proposed rule to eliminate safe harbor protection for back-end rebates in Medicare Part D that is referenced above if it is finalized. Assuming you are confident that antitrust laws do not prevent your company from offering up-front discounts, specifically, do you envision that your company lowers the list price of a drug to the current after- rebate net price, offer discounts equal to the current rebate amount, or a combination of both? Answer. If finalized, the rule will result in lower out-of-pocket patient costs at the pharmacy counter and help address the perverse incentives in the system that have been contributing to higher list prices for medicines. We realize that the transition away from rebates toward a point-of-sale discount model will result in a lowering of our net prices. Despite this potential negative financial impact, we support efforts to eliminate rebates because we believe the new model will be good for patients. As currently written, the proposed rule only applies to the Medicare and Medicaid managed care segments of the market. It will be important to have any rebate reform apply to both government programs and the commercial market as that will also lead to a lowering of list prices as well. A bifurcated market will make it more challenging for manufacturers to reduce list price since the commercial market covers more than 50 percent of Americans with insurance and represents over half of the business for most manufacturers. If the proposed rule is modified to apply to all market segments, we would evaluate the best options to arrive at a net price that ensures patients have access to our medicines. Decisions would be made on a product by product basis given that each therapeutic class has its own set of competitive and access dynamics. As such, we expect to use both list price reductions and up-front discounts to achieve these lower net prices. To ensure these benefits reach patients, it will be important for Congress to ensure that plans do not create new barriers or restrictions that hinder patient access and undermine the spirit of the rule. Question. To what extent are the back-end rebates your company currently offers contingent on the amount of market share realized for your drugs as a result of Part D plan formulary placement and other techniques? Answer. Pfizer's contracts with Part D Health Plans and PBMs negotiating on their behalf do not make rebates contingent on market share. Question. Please provide a breakdown of percentage of sales that go to each payer (including Medicare, Medicaid, private pay, other) and a similar percentage by volume of the total number of each drug compared to total volume. Please provide this data for the most recent year available. Answer. Pfizer's prescription pharmaceutical products are sold principally to wholesalers, and therefore the Company does not have sufficient visibility into wholesaler distribution at the channel level to provide responses as requested. We welcome the opportunity to discuss with your committee staff the confidential information requested and what we maintain in the ordinary course of business. Question. Do your companies hire consultants or lobbyists to promote products at State Medicaid Pharmacy and Therapeutics Committees? Answer. No. Question. To whom do you disclose advocacy activities surrounding State Medicaid programs, if at all? Answer. Pfizer is committed to the principle of transparency--the disclosure of activities reflecting participation in efforts of public interest. These activities include such areas as funding for educational activities, the status of Pfizer's U.S. pharmaceutical post-marketing commitments, Pfizer's pipeline of experimental medicines, the registration and reporting of results of clinical trials, political contributions in the United States and payments to U.S. health care professionals. The information we report includes grants to support independent medical education, support for fellowship, scholarship and visiting professorship programs, grants to patient organizations, medical and scientific associations, and academic or other medical centers, charitable contributions, health care-related support to civic organizations and health care-related non-promotional sponsorships to organizations. For descriptions of types of support, please visit https://www.pfizer.com/purpose/ independent-grants/transparency-in-grants. Any Medicaid specific advocacy funding we provide would be captured in these reports. Question. Please describe how the costs of programs are accounted for within your company's financial statements. Please also describe the types of market information, such as prescribing and use patterns, that your company collects from different types of patient assistance programs and patient hub services. Answer. Pfizer's patient assistance program is a charitable free drug program that provides commercially available Pfizer medicines free of charge to financially eligible uninsured and underinsured patients. Separate from the Pfizer patient assistance program, Pfizer also offers patient support programs, which are limited access reimbursement support offerings to patients to assist with obtaining access to and coverage of a prescribed Pfizer medicine. The product and administrative costs for the patient assistance program are charged against Pfizer's Selling, General and Administrative Expenses line in the income statement. Pfizer gathers data in the course of providing free drugs to patients via the patient assistance program. We can bucket data collection in several ways: (1) Transactional data--Utilized to determine patient eligibility to receive free access to a physician-prescribed therapy. (2) Operational data--The operational data is utilized to provide free access to medicines to the eligible patient and the following is reported at an aggregated level: (i) program utilization trends; (ii) application processing trends; (iii) patient coverage trends; (iv) channel utilization (distribution versus pharmacy); (v) fulfillment and order processing days; and (vi) call metrics. Pfizer gathers the following two categories of data when providing patient support programs: (1) Transactional--Utilized to assist in accessing prescribed therapy and to determine insurance coverage for the patient. This information contains data such as the outcome of a benefits investigation, information to determine the financial need and eligibility for patient support, and disposition of the patient case (i.e., sent to a specialty pharmacy for fulfillment, sent to Pfizer patient assistance program, triaged to other financial options, or rejected/denied). (2) Operational--These fields could include primary and secondary payers, out-of-pocket costs borne by the patient, turnaround time to obtain insurance approval, prior authorization requirements, number of cases requiring appeals, and other data elements on access dynamics. In addition to these elements, Pfizer will collect relevant adverse events as required by Pfizer drug safety. Question. Please provide a list of all contributions since January 1, 2014, that your company has made to any tax exempt organizations working on issues related to drugs within your product lines, including but not limited to patient groups, disease awareness groups, medical or professional societies, universities or hospitals, industry associations or leagues. For each contribution, please provide the name of the organization that received the donation, the date the donation was made, the amount of the donation, and a description of the purpose of the contribution (i.e., was the contribution for the general fund, a specific purpose to a specific program, or continuing medical education). Please also note whether the contribution was unrestricted or restricted; if it was restricted, please explain all restrictions. Finally, if your company maintains a foundation or other separate charitable arm, please provide the name of all such entities, and list all donations made from that entity or entities. Answer. Information about Pfizer's charitable giving is listed on Pfizer.com. Please see the annual reports dating back to 2008 available at https://www.pfizer. com/purpose/independent-grants/transparency-in-grants, which include the recipient name, the contribution amount and the annual quarter in which it was made, and a description of the relevant program or project. This data is updated each quarter. Data from Q4 2018 is currently being analyzed and will be available at the end of March 2019. The annual reports include various funding types and recipient types. However, in collating this data, Pfizer does not characterize the organizations as working on issues related to drugs within product lines, or contributions as restricted or unrestricted. Consequently, the requested data is not available in that format. Note that information regarding charitable contributions from the Pfizer Foundation is not included in these reports, so Pfizer has included a Pfizer Foundation Grant Summary as Exhibit 3. The Pfizer Foundation has been working to expand health-care access to people around the world for nearly 65 years. The impact of this work is significant and far-reaching, helping underserved individuals from diverse backgrounds in remote corners of the globe. Through the Pfizer Foundation's global health strategy, we provide grant and investment funding to support organizations and social entrepreneurs in an effort to improve health care delivery in low-and middle-income countries and increase access to health care for underserved communities. Question. Pay for delay agreements cost consumers and taxpayers billions in higher drug costs every year. The FTC has gone after drug companies that enter into these settlements where the brand pays the generic company to keep its lower cost alternative off the market. I'm the lead Republican sponsor of S. 64, the ``Preserve Access to Affordable Generics and Biosimilars Act,'' which would help put an end to these deals. Do you agree that these pay-off agreements keep drug costs high for patients because they delay competition? Answer. Pfizer wants to work with you on this issue because we agree that gaming the patent system is unacceptable. The company's patent settlements do not involve ``pay for delay.'' On the contrary, when Pfizer settles patent litigation with generic firms, it does so on terms that generally enable entry of generic competition earlier than the expiration of its patents and that do not involve unlawful reverse payments. Pfizer's patent settlements thus involve lawful compromises that accelerate patient access to lower cost generics relative to the expiration of its patents. Question. Has your company ever entered into these kinds of settlements with a generic company? Answer. No. On the contrary, when Pfizer settles patent litigation with generic firms, it does so on terms that generally enable entry of generic competition earlier than the expiration of its patents and that do not involve unlawful reverse payments. Pfizer's patent settlements thus involve lawful compromises that appropriately resolve patent disputes and accelerate patient access to lower cost generics relative to the expiration of its patents. While Pfizer has been the target of plaintiff lawyer driven class action lawsuits challenging certain of its settlements with generic companies, we believe these lawsuits are without merit and are vigorously asserting the pro-competitive nature of these settlements in court. Question. Do you support the pay for delay bill? Answer. Pfizer agrees that gaming the patent system is unacceptable. We hope to work with you on legislation that prohibits anticompetitive patent settlements that is prospective, clearly defines violations and what is deemed to be an improper settlement and does not presume all patent settlement agreements are per se illegal and anticompetitive. Laws or actions to restrict certain kinds of pharmaceutical patent settlements could prevent some pro-consumer settlements that bring generics to market prior to patent expiration-- patent settlements often include an agreement that enables generics to enter the market earlier than the date of patent expiration, speeding patient access to more affordable generic options. rebate traps/walls Question. I'm increasingly concerned about the effect of so-called ``rebate traps'' or ``rebate walls'' on patients' access to quality, lower cost medicine. I understand there is ongoing litigation challenging these practices as anti-competitive. Does your company engage in the bundling of rebates over multiple products? If so, why? And what benefit does the consumer gain from that? Answer. Pfizer does currently bundle rebates over multiple products. Pfizer does offer bundling arrangements to obtain formulary positions that allow patients to access our medicines that otherwise might be restricted. Question. Does your company view these practices as anticompetitive or harmful to patients' access to quality, lower cost medicine? Answer. Pfizer does not believe bundling is inherently anticompetitive and in certain circumstances can be procompetitive. However, Pfizer does not tie bundled rebates to blocking lower cost competitive agents and believes that when a firm with monopoly power uses such practices to block lower cost alternatives the conduct is anticompetitive. Question. If a policy were adopted to eliminate rebates, or to require that rebate savings be passed on to the consumer, would that in and of itself solve the issue of rebate ``traps'' and ``walls''? And would consumers benefit from such a policy? Answer. A policy that moves rebates to discounts would not in and of itself eliminate the ability of a market leader to block a lower priced medicine. In both Medicare and commercial, the Health Plan is still responsible for the majority of the drug cost and would therefore receive the majority of the discount. The Health Plan or PBM would still need to transition patients from the higher priced market leader to the lower priced product in order to realize the savings from the discount. Based on internal analysis, Pfizer expects that moving from a rebate to a discount model will weaken a market leader's ability to restrict other less expensive products, but it would not eliminate the possibility. drug pricing Question. When setting the list price of a drug, does your company consider regulatory costs or compliance? If so, how specifically do those factors affect the list price of a drug? Please provide at least one specific example, if applicable, from your current product portfolio. Answer. The Food and Drug Administration is the primary regulatory body for the pharmaceutical industry and is largely focused on the safety, quality, and efficacy of medicines. The price of a new medicine is most directly influenced by the value that the medicine may bring to patients and society. Inherent in the value any product Pfizer brings to the market are the quality, safety, delivery, efficacy, and reliability of our medicines. These regulatory and compliance factors are part of the underlying investments to identify a product's value and are amongst the many factors we consider when we determine a launch price or make a decision to change a price. Question. When setting the list price of a drug, does your company consider the risk of liability or litigation? If so, how specifically do those factors affect the list price of a drug? Please provide at least one specific example, if applicable, from your current product portfolio. Answer. Liability and litigation are not primary considerations when setting the list price of a medicine; the value that a product may bring to patients and society is the most important factor considered. ______ Questions Submitted by Hon. Pat Roberts Question. What role do you see value-based agreements (VBAs) playing in the effort to reduce prescription drug costs? What potential do these arrangements have to find the ``sweet spot'' between controlling costs to patients and encouraging innovation of new drugs? Answer. Value-based agreements (VBA) provide a framework for manufacturers to be compensated based on a product's value to patients and the overall health-care system. Although there are different constructs for VBAs, the basic premise is that the net price for a product will ultimately be derived based on an agreed upon performance metric (e.g., clinical, financial, adherence, etc.). Therefore, VBAs can play a role in reducing prescription drug costs by ensuring that net prices are linked to value. As we shift to a system that rewards value, manufacturers will be incentivized to focus research and development (R&D) investments in disease areas where there are unmet needs, to focus on best in class or first in class medicines, and to design trials that provide the necessary evidence to demonstrate the value of a medicine beyond the regulatory standards of safety and efficacy to include the evidence to support reimbursement. If manufacturers deliver medicines of value, the system will reward the manufacturer which encourages innovation of new drugs. Question. How can VBAs help lower what patients pay out-of-pocket? Answer. Value-based agreements (VBA) provide a framework for manufacturers to be compensated based on a product's value to patients and the overall health-care system. There are many different types of VBAs including those based on clinical and/or financial performance metrics for a product. Based on the outcomes achieved, payers use this information to inform how they cover products. Products that perform better should be covered in a more favorable manner which often includes lower out-of-pockets costs for patients which is a benefit to patients in the near term. In the long term, patients can also benefit from other savings either directly, (e.g., reducing spending on other medications, lowering medical costs from reduced hospitalizations, doctor's visits, etc.), or indirectly through lower premiums based on reductions in total cost of care. Question. Can Congress do more to allow for and encourage the use of VBAs? Answer. VBAs are in the very early stages of development in the United States. Many payers and manufacturers have tested different concepts, but to date VBAs have not achieved scale. There are multiple reasons why VBAs represent a small fraction of manufacturer/payer contracts (e.g., access to data, difficult and costly to administer, etc.). There are certain aspects of the current U.S. regulatory landscape that are perceived by many as not only complicating VBA implementation but in some cases limiting their rapid uptake. Stakeholders have frequently identified two key regulatory hurdles as limiting the expanded adoption of VBAs: (i) the Anti-Kickback Statute and (ii) the Medicaid Best Price calculation requirement. While these regulations serve important roles within the current volume-based reimbursement system they do not contemplate innovative value-based arrangements which have resulted in a lack of clarity on how to account for these under the current regulatory framework. Ultimately, an expansion of VBAs will require reforms to existing regulations that enable more flexibility in designing VBAs. ______ Questions Submitted by Hon. Michael B. Enzi Question. More than 10 years ago, I worked on a bipartisan basis with my good friends Ted Kennedy and Orrin Hatch to develop a biosimilars approval pathway. One of the difficult things was accounting for the differences between biosimilars and generics. I have said before that if a drug was a three-bedroom, two-bath home, a biologic would be a skyscraper. The size and complexity of the items are just that different. I understand that it is much harder to build a skyscraper without blueprints than a house. Even though the science has come a long way since then, there aren't as many biosimilars on the market as we might have hoped. Do you think the incentives in the law appropriately account for the differences between biosimilars and generics? Answer. The Biologics Price Competition and Innovation Act (BPCIA) created an abbreviated pathway for the licensure of biosimilars, including interchangeable biologic products, and created the framework biosimilar applicants and reference product sponsors use to resolve patent disputes. There are currently seven biosimilars on the market in the United States, and there are a number of biosimilars currently in development. The FDA has approved a total of 18 biosimilars to date. Nevertheless, the success of the BPCIA lies in the increased use of these products, which will provide savings to both the patient and the taxpayer. To date, there have been two key policies that have helped support the biosimilars marketplace: 340B pass-through status for biosimilars and the separate billing/J code policy for biosimilars. The separate billing/J code policy for biosimilars has aided in the prompt reimbursement of biosimilars for physicians, which is critical in supporting uptake of biosimilars. The separate billing/J code also provides Congress and CMS with transparency on the average sales price of the biosimilar versus the reference biologic. Below is a table outlining the latest Medicare published average sales prices for the reference biologic Remicade and both of the biosimilars on the market for Remicade, Pfizer's Inflectra and Merck's Renflexis.\2\ It is important to note that the average sales price (ASP) for both biosimilars is lower than the ASP of the reference biologic. Yet, the market share of the Inflectra biosimilar remains at 6 percent in open systems (which excludes the VA and Kaiser, which are closed systems where the insurer is the payer, the prescriber and the provider). --------------------------------------------------------------------------- \2\ https://www.cms.gov/Medicare/Medicare-Fee-for-Service-Part-B- Drugs/McrPartBDrugAvg SalesPrice/2019ASPFiles.html. ------------------------------------------------------------------------ Q4 2018 CMS Q1 2019 CMS Q2 2019 CMS HCPCS Code ASP ASP ASP ------------------------------------------------------------------------ Remicade (reference J1745 $743.71 $723.10 $677.60 biologic) ------------------------------------------------------------------------ Inflectra Q5103 $569.01 $529.37 $502.72 (biosimilar) ------------------------------------------------------------------------ Renflexis Q5104 $599.20 $575.64 $552.00 (biosimilar) ------------------------------------------------------------------------ The 340B pass-through policy for biosimilars has been another positive policy to support uptake of biosimilars in 340B hospitals. The 340B pass-through policy provides a temporary ``level playing field'' for the biosimilar and the reference biologic. Under the reimbursement model of ASP + x%, providers are incentivized to use a higher cost product to drive a higher ``+ x%'' reimbursement. As in the case of biosimilars, when the biosimilar has a lower ASP the reimbursement is lower to the health-care provider/340B hospital. The pass-through policy provides temporary reimbursement parity for lower cost biosimilars. This policy has encouraged 340B hospitals to adopt biosimilars and gain experience and confidence in using them. Despite these current policies, other adverse incentives that favor higher-cost originator biologics are keeping biosimilars from reaching patients. In many cases, payers decline to include lower-cost biosimilars or generics in their formularies because they would risk losing the rebates they could receive by covering higher-cost medicines. Question. I know there are proposals to essentially pay more for biosimilars to make them more attractive, but that is not exactly what we were intending when we wrote the law. Can you talk about adverse incentives in the market and any barriers to market penetration that we might address to help improve patient access to these lower cost products? Answer. Ninety percent of the medicines Americans take are generics and competition from these drugs keeps prices low in most cases. The biologics market, where some of the most expensive drugs exist, needs similar competition. The market today has already seen demonstrated savings as high as 40 percent relative to the branded product. In Europe, biosimilars have obtained a market share of over 60 percent on some products. However, in the United States, our biosimilar, Inflectra, has captured only 6 percent, despite the fact that its average selling price (ASP) is more than 25 percent lower than the originator product. With more competition, Pfizer hopes even further savings can be realized. We believe some of the adverse incentives and barriers to market penetration include: 1. The Rebate Trap: Brand-name biologic companies are using maneuvers to block biosimilar competition such as higher rebates and exclusionary contracts. 2. Misinformation: We believe that some physician and patient- directed materials created by brand companies mischaracterize biosimilars, creating doubt and confusion about the safety and efficacy of biosimilars. As defined by statute, an approved biosimilar must be highly similar to and have no clinically meaningful differences from the reference product and must have the same mechanism of action (to the extent the mechanism(s) of action of the reference product are known) as the reference product. Thus, by definition, biosimilars are safe and efficacious treatments relative to the reference product and must work in the same way as the reference product. Any information disseminated by reference product sponsors to suggest or imply otherwise should be promptly addressed by the FDA. 3. Need for incentives: Legislative ideas to promote biosimilar uptake could include a shared savings biosimilar model; reduced patient cost sharing for biosimilars. Although the biosimilar market in the United States is still relatively new, Pfizer's experience has been that anticompetitive conduct by brand-name biologic manufacturers, combined with the lack of policy measures to support appropriate uptake of biosimilars, have contributed to a slow uptake. Therefore, we encourage you to consider measures to help incentivize the use of biosimilars, which can substantially lower Medicare costs with demonstrated savings to date as high as nearly 40 percent relative to the branded biologic. In addition to stopping anticompetitive behavior (either through government enforcement or in the courts through private litigation), some key policy initiatives we believe will support the uptake of biosimilars in the United States include: Waiver of Part B Patient Coinsurance for Biosimilars for a certain period of time. CMS should waive Part B patient coinsurance amounts for biosimilars. Cost-sharing changes could be applied at the Healthcare Common Procedure Coding System (HCPCS) level. This would not change the overall payment for a biosimilar; however, it would change the beneficiary's payment percentage. CMS should pursue a CMMI model designed to increase access to biosimilars, including a ``shared savings'' model whereby Medicare savings associated with prescribing a biosimilar, as compared to a reference biological, would be shared with providers. CMS should maintain the current biosimilar pass-through status as this provides biosimilars with a ``level playing field'' with their higher priced reference biologic competitors. CMS should create payment incentives for plans by contracting with a measure developer for a biosimilar use measure for the STARS program, which would correct other adverse incentives for biosimilar uptake for Medicare Advantage plans. ______ Questions Submitted by Hon. John Cornyn Question. We continue to hear that rebates negotiated off of the list price of a drug are both good and bad. Pharmacy benefit managers and plans have argued that rebates are used to lower premiums across the board and that it is the best way to seek a price concession on otherwise expensive drugs. Your industry argues that these payers are insisting on higher rebates that can only be achieved by raising list prices. But patients often lose under this system, with out of pocket costs being tied to list price. Insulin patients appear to be routinely impacted by this perversity in the system. Please explain to the committee how your company would reduce list prices if rebates were no longer a part of the equation? Answer. If finalized, the rule would result in lower out-of-pocket patient costs at the pharmacy counter and help address the perverse incentives in the system that have been contributing to higher list prices for medicines. In 2019, Pfizer expects to pay billions of dollars in rebates to ensure patients with pharmacy benefits coverage in Medicare Part D and patients in commercial plans have access to our medicines. If the proposed rule to share rebates with consumers at the point of sale is finalized, we estimate that seniors taking Pfizer medicines could save $270 on average per year, and up to $574 per year for certain Pfizer medicines, through lower cost sharing--and that would outweigh any premium increases. As currently written, the proposed rule only applies to the Medicare and Medicaid managed care segments of the market. It will be important to have rebate reform changes apply to both government programs and the commercial market. A bifurcated market will make it more challenging for manufacturers to reduce list price since the commercial market covers more than 50 percent of Americans with insurance and represents over half of the business for most manufacturers. If the proposed reform is modified to apply to all market segments, we would evaluate the best options to arrive at a net price that ensures patients have access to our medicines. Decisions would be made on a product by product basis given that each therapeutic class has its own set of competitive and access dynamics. Question. What assurance can you provide that you would in fact lower your prices? Answer. If the rule is finalized consistent with the aforementioned concerns, Pfizer is confident patients will benefit from savings of any price concessions at the point of sale. Question. What actions should be taken to ensure that patients are actually seeing the benefits of lower out of pocket costs? Answer. We strongly support ensuring that patients receive the benefit of rebates at the pharmacy counter and look forward to working with Congress and HHS on this issue. We encourage Congress to ensure that plans do not impose new barriers or restrictions to access that undermine the spirit of the rule and prevent patients from benefiting from the savings. Question. If rebates are driving high list prices for drugs as drug manufacturers' claim, why do you think that Part B drugs, which have no PBM rebates, are also seeing significant price increases? Whose fault is that? There are rebates involved with infusion medicines (Medicare Part B drugs), and Pfizer is willing to engage with your staff in general terms to explain the relationship and negotiations between manufacturers and payers such as insurers and PBMs for drugs in this space. Pfizer also believes there are other ways to reform the Part B payment system to move away from incentivizing the use of more costly drugs. One solution we support for reforming Part B is a Competitive Acquisition Program (CAP) to allow vendors to deliver and bill Medicare for drugs, starting in a few cities. We believe this will inject competition into the program. Biosimilars are another solution. Pfizer is fully committed to the goals set by Congress to bring new biosimilars to market, ensuring that patients have access to a wide range of treatment options at a competitive, affordable price. The market today has already seen demonstrated savings as high as 40 percent relative to the branded product. With more competition, we hope even further savings can be realized. rebate traps Question. Pfizer's biosimilar to Janssen's Remicade has struggled to gain market share, despite being priced at a significant discount to the biologic. Please explain the market challenges you are seeing with this product. How does the practice of drug companies ``bundling'' the prices of product portfolios and rebates associated with these drugs limit competition and access to lower-cost biosimilars? Answer. As more fully laid out in Exhibit 4, the primary barrier to Inflectra's uptake is an anticompetitive contracting scheme that targets both the payer (i.e., insurer) channel and the health-care provider (i.e., hospitals, clinics and doctors) channel. The centerpiece of the scheme is the ``rebate trap'' that uses pricing penalties (i.e., the loss of significant rebates) to coerce insurers to enter into exclusive deals that cover Remicade while effectively blocking Inflectra from coverage. Multi- product bundling is just one aspect of the conduct. Despite bringing a lower-cost version of Remicade to market, this biosimilar has captured less than 10 percent of the market. Question. Do you attribute this to exclusionary contracts or ``paying for position'' to keep your product off formularies? Please explain this practice and how it keeps lower-cost drugs out of the hands of patients. Answer. Pfizer attributes low uptake to an anticompetitive contracting scheme as described above in response to Question 1. This is particularly concerning not only because of the direct impact regarding the health-care system's spend, but also because it could become the playbook by which innovator biologics thwart entry by biosimilars in the future. This could inhibit significant competition to biologics going forward and act as a disincentive for companies to invest in developing biosimilars. ______ Questions Submitted by Hon. Steve Daines Question. As an advocate for improving Montanans' access to low- cost medications, I've been a champion of the Creating and Restoring Equal Access to Equivalent Samples (CREATES) Act, which would combat anticompetitive practices used by some brand-name pharmaceutical companies to block or delay competing generic drugs from entering the market. During the hearing when I asked if your company had ever withheld samples from generic manufacturers, you answered emphatically no. Yet, according to the Food and Drug Administration (FDA), generic drug makers have made inquiries with the agency claiming they were unable to access samples provided by Pfizer and AstraZeneca that are needed to conduct studies to produce low-cost generic drugs. Do you agree that denying generic drug manufacturers access to samples keeps drug costs high for patients due to lack of competition? Has your company refused to sell samples or placed any barriers in the way of generic drug makers acquiring samples? Are you aware of any outstanding requests for samples? How does your company work to prevent abuses in the sample system? Answer. As a patient-focused company and leading manufacturer of innovative, generic, and biosimilar medicines, Pfizer supports innovation and a strong, competitive marketplace. Consistent with these values, Pfizer does not block generic manufacturers from purchasing our products, and it has never been our policy to do so. Generic manufacturers are treated the same as any other customer seeking to purchase our products. Pfizer is not aware of any current, unfulfilled requests from a generic manufacturer to purchase a Pfizer product. Generic manufacturers seeking to purchase Pfizer products should request the product from Pfizer's authorized distributors or, if the product is not available at a distributor, from Pfizer directly, the same as any other Pfizer customers. Pfizer's website includes a list of our authorized distributors, from which customers (including generic companies) may purchase most Pfizer products (see https://www. pfizer.com/products/medicine-distributors). For products that are not available via our authorized distributors and that are not in extreme drug shortage or unavailable due to a recall, customers can contact Pfizer's Customer Service center at 1-800-TRY-FIRST (1-800-879-3477) to purchase product directly from Pfizer. The telephone number for Pfizer's Customer Service center is also included on our website at https://www.pfizer.com/contact. Pfizer makes its products available for sale to appropriately licensed entities at Pfizer's listed price and on Pfizer's standard terms of sale. We do not have any agreements with authorized distributors that block the sale of Pfizer's products to generic manufacturers. Regarding the FDA List (the List), while Pfizer supports FDA's (the agency) goal of providing transparency, Pfizer is concerned that the List lacks certain key information and context and, as currently presented, may create the misleading impression that all products on the List are the result of bad faith attempts to block generic manufacturer access to samples. The appearance of a product on the FDA List means only that a generic manufacturer informed the agency at some point in time that it was having difficulty purchasing the listed product. FDA's own disclaimer states that the agency has not independently investigated or confirmed whether a generic manufacturer actually made a request to purchase product, and to whom.\3\ The FDA List also lacks several important pieces of information that would enable a New Drug Application (NDA) holder to investigate its appearance on the List. The List does not include: (1) which generic manufacturer made the request; (2) when and to whom the generic manufacturer made the request (e.g., to a wholesaler, directly to the NDA holder); (3) whether the generic manufacturer that made the inquiry was thereafter able to obtain product; and (4) any reason(s) why a generic manufacturer may not have been able to obtain product (e.g., a recall). Finally, Pfizer notes that FDA does not currently inform an NDA holder in real time when a generic manufacturer notifies the agency that it is having difficulty obtaining product. Had the agency informed Pfizer at the time it received the inquiries noted on the FDA List, Pfizer could have then undertaken its own efforts to resolve the issue. Pfizer communicated its concerns about the FDA List to the agency in May 2018. For your information we have included Pfizer's letter to FDA on this topic and the agency's response (see Exhibits 1 and 2 in the Appendix). --------------------------------------------------------------------------- \3\ (https://www.fda.gov/Drugs/DevelopmentApprovalProcess/ HowDrugsareDevelopedandAp proved/ApprovalApplications/AbbreviatedNewDrugApplicationANDAGenerics/ ucm607738.htm). There are three new drug applications owned by Pfizer on the FDA List: Embeda (NDA 022321), Tikosyn (NDA 020931) and Hemabate (NDA 017989). Embeda offers a good example of the List's shortcomings. Pfizer acquired King Pharmaceuticals (the previous NDA holder of Embeda) in March 2011, and two weeks later determined that Embeda needed to be recalled from the U.S. market due to stability issues. After diligently addressing the issues that led to the recall, Pfizer relaunched Embeda to the U.S. market in January 2015, and it is available for purchase via Pfizer's authorized distributors. However, one consequence of the recall, was that Embeda was not available in the U.S. market for almost 4 years which may explain why a generic manufacturer had a problem obtaining it during those years. The FDA List does not specify when the generic manufacturer's inquiry regarding Embeda was made nor does the FDA List indicate that several generic applications for Embeda had been submitted to FDA in 2010 (which means that before the recall, several generic manufacturers were successfully able to purchase Embeda, conduct the necessary testing, and file Abbreviated New Drug Applications (ANDAs)). Pfizer has not identified any recent inquiries from generic manufacturers seeking to purchase --------------------------------------------------------------------------- Embeda that have not been fulfilled. The circumstances around Tikosyn also illustrate the List's shortcomings. Pfizer was able to identify a single inquiry made by a generic manufacturer directly to Pfizer to purchase Tikosyn in 2014. At that time, Tikosyn was subject to an FDA imposed Risk Evaluation and Mitigation Strategies (REMS) with Elements to Assure Safe Use (``ETASU'') that restricted distribution, so Pfizer responded by asking the manufacturer to obtain written confirmation from the FDA that Pfizer's provision of the product to the generic manufacturer would not be considered a violation of its REMS. The generic manufacturer did not contact Pfizer further, and Pfizer never received any written correspondence from the agency. FDA subsequently removed the REMS for Tikosyn in 2016, and multiple generic versions of Tikosyn are now approved, the first generic approval occurring in June 2016. This context is not reflected in FDA's List. Finally, with respect to Hemabate, this product was previously subject to certain restrictions on distribution (i.e., it was sold only to customers with medical and surgical intensive care centers) to ensure its safe and appropriate use. This distribution approach was established by the previous NDA holder (Pharmacia) and it continued following Pfizer's acquisition of Pharmacia in 2003. Pfizer discontinued this approach in early 2018 after determining that it was no longer necessary, and this product is now available through our authorized distributors. During the time when Hemabate was under restricted distribution, it was not available at Pfizer's authorized distributors, but had a generic manufacturer approached Pfizer's Customer Service center directly, we would have been able to address the inquiry. Pfizer's Customer Service was not able to identify any specific requests from a generic manufacturer to purchase Hemabate that have not been fulfilled. We hope that this information explains the apparent discrepancy between Mr. Bourla's testimony and the appearance of these Pfizer products on the FDA List, and demonstrates Pfizer's diligence on these issues and commitment to a competitive marketplace. ______ Questions Submitted by Hon. Todd Young re-evaluating business strategies in foreign countries Question. Since taking office, President Trump has made reducing drug prices one of his highest priorities--and has repeatedly spoken about his frustration with the U.S. subsidizing the costs of pharmaceuticals for the rest of the world. He has gone so far as to issue proposals, like the International Pricing Index (IPI) Model, in an attempt to bring down prescription drug prices. With the increased scrutiny of the industry and of the drug supply chain as a whole in the United States, have any of your companies re- evaluated your business strategy in foreign countries? Answer. Pfizer's purpose is breakthroughs that change patients' lives; all aspects of Pfizer's business model are infused with this purpose. It is Pfizer's priority to make our medicines and vaccines available and accessible to all patients who need them, regardless of where they live. Proposals to implement international reference pricing for the U.S. market would have far-reaching consequences to patient access, innovation and our business strategies both in the United States and in foreign countries. If the United States were to implement the proposed International Price Indexing (IPI) model, we believe that a change of this scale could be very disruptive, challenging our ability to reach patients both inside and outside of the United States in a timely manner while fulfilling commitments to our shareholders and further investing in R&D. Question. If not, then why? Answer. Pfizer agrees that more must be done to address foreign pricing differentials. We want to continue to work with policymakers on solutions to ensure other countries appropriately recognize the value of innovation. Pfizer supports the concept of ``shared value for innovation'' because it promotes global fairness. This means that all nations recognize the importance and benefits of medicines to patients and society and the significant investments required to develop them, and that all patients should benefit, no matter where they live. If foreign countries were to increase their support for shared value for innovation, American patients would benefit based on increased innovation, drug launches, competition and more access to new medicines. Question. If a proposal, like IPI, were implemented, would it force your companies to potentially ``walk away from the negotiating table when other countries demand low prices subsidized by America's seniors,'' as HHS Senior Advisor for Drug Pricing Reform John O'Brien has said? Answer. While the IPI could lead to potential situations in which a company would ``walk away'' as noted by John O'Brien, pricing is not the only determinant of reimbursement negotiations in foreign countries, many of which employ access controls, restricting patients' ability to receive new innovative medicines. We have concerns with the IPI model. The use of reference pricing is strongly associated with market and patient access delays in countries that have adopted reference pricing, among other cost- containment mechanisms. Pfizer works with governments and health systems around the world to support patients' access to the medicines they need. We strongly believe that flexibility in our ability to set global prices improves access to medicines. Question. What are some of your ideas on how we can ensure Americans aren't shouldering the full cost of pharmaceuticals? Answer. Pfizer believes that developed countries have an important role to play in supporting global innovation ecosystems. As such, we would encourage the United States Government to continue to elevate the innovation agenda in multilateral discussions, with an emphasis on rewarding innovation in health-care delivery, science policy and pharmaceutical breakthroughs (e.g., through the G7). U.S. trade negotiations, such as those with Japan, also provide important opportunities for the United States to secure robust commitments that ensure countries protect intellectual property, provide fair market access for U.S. companies, and appropriately recognize the value of innovation. Pfizer also believes that there are other ways to reform the Part B payment system to move away from incentivizing the use of more costly drugs. One solution we support for reforming Part B is a Competitive Acquisition Program (CAP) to allow vendors to deliver and bill Medicare for drugs, starting in a few cities. We believe this will inject competition into the program. Biosimilars are another solution. Pfizer is fully committed to the goals set by Congress to bring new biosimilars to market, ensuring that patients have access to a wide range of treatment options at a competitive, affordable price. The market today has already seen demonstrated savings as high as 40 percent relative to the branded product. With more competition, Pfizer hopes even further savings can be realized. foreign countries' pricing and reimbursement Question. President Trump and Secretary Azar have both repeatedly described their frustrations with ``foreign freeloading'' of U.S. drugs in the last year. ``When foreign governments extort unreasonably low prices from U.S. drug makers, Americans have to pay more to subsidize the enormous cost of research and development. . . . It's unfair and it's ridiculous, and it's not going to happen any longer.'' Do you agree that because of foreign countries' pricing and reimbursement systems, U.S. patients and innovators are shouldering the burden for financing medical advances? Answer. Pfizer agrees that more must be done to address foreign pricing differentials. Wealthy countries should reimburse innovative medicines based on fair value. As stated above, ``foreign free- loading'' has a significant impact on the U.S. biopharmaceutical industry's investments in continued innovation. If the United States secures agreements that ensure countries protect intellectual property, provide fair market access for U.S. companies, and appropriately recognize the value of innovation, this will help ensure U.S. patients continue to have access to innovative medicines. Question. How do foreign countries' pricing and reimbursement systems affect our prescription drug costs? Answer. The U.S. health-care system offers patients more choice and faster availability of innovative medicines. While government-run health systems aim to provide care to their people, they are often challenged to provide fast and easy access to the latest innovations. These governments often have to make choices between paying for health care and other government priorities. The United States allows companies and providers to set prices that reflect the benefits to patients and societies. This includes ensuring that health-care professionals and patients have choices for individualized care, that there is competition among companies, and that their expectations for access to the latest medical advances are met. Some developed countries rely on price controls and other government regulations to set the prices of health care, including medicines. This may result in some lower prices but can also result in restrictions on who is eligible to receive a covered medicine. A recent op-ed in The Wall Street Journal pointed out that of the 45 new drugs that FDA approved in 2015, all were covered by Medicare in the United States in 2017, but only 19 in France, 13 in Canada and 11 in Australia.\4\ --------------------------------------------------------------------------- \4\ https://www.wsj.com/articles/how-to-reduce-prescription-drug- prices-first-do-no-harm-1155 0100537. However, prices are not always higher in the United States. Nine out of ten drugs that patients pick up at the pharmacy are generics, and these drugs are less expensive than they are in Europe, Japan, China or many countries around the world. The U.S. system is the most --------------------------------------------------------------------------- efficient system for delivering lower-cost generics to patients. Pfizer supports the concept of ``shared value for innovation'' because it promotes global fairness. This means that all nations recognize the importance and benefits of medicines to patients and society and the significant investments required to develop them, and that all patients should benefit, no matter where they live. If foreign countries were to increase their support for shared value for innovation, American patients would benefit based on increased innovation, drug launches, competition and more access to new medicines. Question. Are foreign governments taking note of the concerns being raised by the Trump administration and have they responded in any way? Answer. Pfizer believes that other governments are indeed taking note of the administration's focus on health-care spending. Question. Has there been any noticeable change in any of our trade agreements since these concerns have been raised by the Trump administration? Answer. The Trump administration recently signed the U.S.-Mexico- Canada Agreement (USMCA), which includes important commitments that will help companies like Pfizer continue to innovate to bring new therapies to patients. For example, the agreement includes a commitment to provide 10 years of regulatory data protection for biologics. This commitment had not been included in any trade agreement negotiated prior to USMCA and is an important achievement. The Trump administration is also pursuing new bilateral trade negotiations with Japan, the EU, and the UK; because the negotiations have not yet concluded, however, it is premature to comment on how those agreements may compare to other U.S. trade deals. medicaid closed formulary proposals Question. In an attempt to bring down drug costs, various States have been exploring whether to exclude certain drugs from its Medicaid program. For example, the State of Massachusetts' recently asked CMS for permission to create a closed formulary where the State Medicaid program would pick at least one drug per therapeutic class. CMS denied their waiver request citing violation of Federal law, but this proposal does bring up important questions on how to contain drug prices in State Medicaid programs. If the principles of the Medicare Part D program--including the necessary patient protections--were applied to State Medicaid programs, do you think it lower drugs costs while ensuring access to patients? Answer. Pfizer supports efforts to ensure patients have access to medicines. Studies suggest that allowing more choice of medications has positive results for patients: lowering the chances of drug interactions and adverse events and increasing the efficacy of treatment.\5\ Years of research have also shown that limiting formularies correlates to poor medication adherence outcomes.\6\ Studies featuring Medicaid recipients with severe health conditions indicate that in many instances, these restrictions can result in negative health outcomes and other outcomes (such as increased incarceration rates) without generating program savings or other intended benefits (and sometimes increasing overall State costs).\7\ --------------------------------------------------------------------------- \5\ See, e.g., DiMasi, ``Competitiveness in follow-on drug R&D: a race or imitation?'', 10 Nat. Rev. Discov. 23-27 (Jan. 2011); Turner et. al, ``Parsing Interindividual Drug Variability: An Emerging Role for Systems Pharmacology,'' Wiley Interdiscip. Rev. Syst. Biol. Med. 221-41 (2015); Mullins et. al, ``Persistence, Switching, and Discontinuation Rates Among Patients Receiving Sertraline, Paroxetine, and Citalopram,'' 25 Pharmacotherapy 660-67 (2005). \6\ See, e.g., Happe et. al, ``A Systematic Literature Review Assessing the Directional Impact of Managed Care Formulary Restrictions on Medication Adherence, Clinical Outcomes, Economic Outcomes, and Health Care Resource Utilization,'' 20 Manag. Care Spec. Pharm. 677-84 (2014). \7\ See, e.g., U.S.C. Schaffer, ``Medicaid Access Restrictions on Psychiatric Drugs: Penny-Wise or Pound Foolish?'', (Feb. 2015), http:// healthpolicy.usc.edu/documents/USC%20Issue%20Brief %20No.%202%20Final.pdf (indicating increased incarceration rates associated with certain access restrictions); Lu, et. al, ``Unintended Impacts of a Medicaid Prior Authorization Policy on Access to Medications for Bipolar Illness,'' 48 Medical Care 4 (Jan. 2010) (finding that while a prior authorization policy in Maine Medicaid was associated with a marked decrease in rates of initiation of bipolar treatments associated with reduction in initiation of nonpreferred agents, the policy had no discernable impact on rates of switching therapy among patients currently on treatment); Farley, et al., ``Retrospective Assessment of Medicaid Step-Therapy Prior Authorization Policy for Atypical Antipsychotic Medications,'' 30 Clinical Therapeutics 1524 (April 2008) (showing, for a group of Medicaid patients with schizophrenia who were subject to a prior authorization policy for atypical antipsychotic medications, significant increases in per member per month outpatient expenditures far exceeded the associated savings in atypical antipsychotic expenditures). --------------------------------------------------------------------------- medicaid ``best price'' Question. In the Trump administration's Blueprint, they suggested that because drug manufactures have to give Medicaid the ``best price'' on drugs, there is no incentive to offer deeper discounts to other payers--both government and commercial--than what is already offered under the Medicaid Drug Rebate Program. Does the Medicaid ``best price'' requirement encourage manufacturers to increase initial prices? Answer. Medicaid Best Price is not a factor in setting our launch prices. Question. What, if any, changes would you suggest we make to the program? Answer. Pfizer encourages HHS to consider how to address the challenges that Medicaid Best Price poses for value-based agreement (VBAs). Specifically, we recommend that: To allow for innovative approaches and risk sharing, a poor outcome should not set a new price for Medicaid. This would allow manufacturers to share more risk with commercial health plans. Approaches to reporting VBAs should be as simple as possible. This would help avoid creating operational challenges for companies that may prevent development of innovative approaches. Manufacturers should continue to have flexibility to make reasonable assumptions in their price reporting, so that reporting approaches can evolve to reflect changes in the dynamic market and contracting environment. outcomes-based contracts Question. In almost all of your testimonies, you highlight your support of outcomes-based contracts and how we need to be shifting our system toward that approach. How will these contracts lower drug costs for patients in both the near term and long-term? Answer. Value-based agreements (VBA) provide a framework for paying for medicines based on their value to patients and the overall health- care system. There are many different types of VBAs including those based on clinical and/or financial performance metrics for a product. Based on the outcomes achieved, payers use this information to inform how they cover products. Products that perform better should be covered in a more favorable manner which often includes lower out-of-pockets costs for patients which is a benefit to patients in the near term. In the long term, patients can also benefit from other savings either directly, (e.g., reducing spending on other medications, lowering medical costs from reduced hospitalizations, doctor's visits, etc.), or indirectly through lower premiums based on reductions in total cost of care. Question. How will they lower overall health-care costs for our Federal programs? Answer. VBAs can be implemented in Federal programs so that the benefits described above can accrue to the Federal programs. Question. What have the preliminary results looked like so far? Answer. VBAs are in the very early stages of development in the United States. Many payers and manufacturers have tested different concepts but to date, VBAs have not achieved scale. There are multiple reasons why VBAs represent a small fraction of manufacturer/payer contracts (e.g., access to data, difficult and costly to administer, etc.). There are certain aspects of the current U.S. regulatory landscape that are perceived by many as not only complicating VBA implementation but in some cases limiting their rapid uptake. Stakeholders have frequently identified two key regulatory hurdles as limiting the expanded adoption of VBAs: (i) the Anti-Kickback Statute and (ii) the Medicaid Best Price calculation requirement. While these regulations serve important roles within the current volume-based reimbursement system they do not contemplate innovative value-based arrangements which has resulted in a lack of clarity on how to account for these under the current regulatory framework. Ultimately, an expansion of VBAs will require reforms to existing regulations that enable more flexibility in designing VBAs. transparency/point of sale Question. In almost all of your testimonies, you express your support for the Trump administration's proposal to allow manufacturers to provide PBMs up-front discounts that are passed onto patients at the point of sale. Do you feel like this proposal will make the transactions within the drug supply chain more transparent? Answer. Pfizer acknowledges that providing discounts pursuant to the safe harbor for point-of-sale price discounts will enhance transparency of net pricing strategies and potentially drive downward pressure on net prices. Nonetheless, Pfizer believes that the proposed safe harbors are good for patients and lay the groundwork for the systemic change needed to create a simpler, more cost effective, and more transparent U.S. health-care system, and we are fully committed to operating in this new system. We are concerned, however, that plans and PBMs could impose new formulary restrictions and utilization barriers to make up for lost rebates that undermine the spirit of the rule and create new access challenges to patients. For patients to receive the benefits of the rule, we urge policymakers to ensure that no new access barriers are created as a way to compensate for lost rebate. Question. If so, would this transparency bring down drug costs-- overall and for specialty drugs? Answer. Only through such transparency can Pfizer and other industry players ensure that discounts and other price reductions directly benefit the patient, which is a critical factor driving Pfizer's support for the Proposed Rule. the relationship between wholesalers and manufacturers Question. When talking about the pharmaceutical supply chain, a lot of focus has been placed on the Pharmacy Benefit Manager. But there's another side of the equation that I'd like to ask about: how do wholesalers negotiate pricing with manufacturers? Answer. Wholesalers pay list price for our products. They may receive prompt pay discounts, which would reduce their net price. Wholesalers also can earn bona fide service fees based on performing services that are important to pharmaceutical manufacturers. Question. What impact does this have on drug costs? Answer. These discounts and fees are relatively consistent across products and do not significantly impact drug costs. Question. What incentives or disincentives do they have to contain price increases? Answer. As a result of the competitive nature of their business, wholesalers do have an incentive to contain price increases. ______ Questions Submitted by Hon. Ron Wyden proposed rebate rule Question. As has been done in many other settings, drug manufacturers said during the hearing that one reason list prices for drugs are high is that pharmaceutical benefit managers (PBMs) demand larger and larger rebates in order for the drug to receive favorable placement on a formulary. You and your colleagues who testified during the hearing stated if the administration's proposal on changes to the anti-kickback safe harbor for pharmaceutical rebates took effect, your company would likely lower list price. Like many Oregonians, I am skeptical drug manufacturers would voluntarily lower their prices. Therefore, would you support legislation that would (1) make similar changes the administration has put forward related to Part D and Medicaid managed care, (2) change the rebate system in a similar way to the proposal for the commercial market, and (3) require drug makers to lower the list price of their drugs equal to the amount of rebates provided today? Answer. Pfizer would support legislation that reforms the current system of rebating to one in which payers are required to use manufacturer provided discounts to ensure that the patient gets the benefit of the discount at the point of sale. We support this reform across all segments of the market where private sector negotiations result in lower net prices including Medicare Part D, Medicaid managed care and the commercial markets. We realize that the transition away from rebates toward a point-of- sale discount model will result in a lowering of our net prices. Despite this potential negative financial impact, we support efforts to eliminate rebates because we believe the new model will be good for patients. As currently written, the proposed rule only applies to the Medicare and Medicaid managed care segments of the market. It will be important to have any rebate reform apply to both government programs and the commercial market as that will also lead to a lowering of list prices as well. A bifurcated market will make it more challenging for manufacturers to reduce list price since the commercial market covers more than 50 percent of Americans with insurance and represents over half of the business for most manufacturers. If the proposed rule is modified to apply to all market segments, we would evaluate the best options to arrive at a net price that ensures patients have access to our medicines. Decisions would be made on a product by product basis given that each therapeutic class has its own set of competitive and access dynamics. To ensure these benefits reach patients, it will be important for policymakers to ensure that plans do not create new barriers or restrictions that hinder patient access and undermine the spirit of the rule. medicaid drug rebate program Question. The Medicaid Drug Rebate Program (MDRP) requires manufacturers to provide a basic rebate and an additional inflationary rebate for both brand and generic drugs. The inflationary rebate is an increasingly substantial part of total rebates due in large part to large increases in drug prices that exceed inflation. Under current law, this inflationary rebate is capped at 100 percent of Average Manufacturer Price (AMP). This is the case even when manufacturers continue to raise their prices well above inflation. Please provide a list of all of your pharmaceutical products that have reached the Medicaid AMP rebate cap in any of the 20 quarters from January 1, 2014 through December 31, 2018. For each drug listed in response to question 1, please also provide a list of which quarters and years each drug hit the cap. Answer. Given the highly confidential nature of the information requested, we would need to discuss the scope of this request with your staff. medicaid drug rebate program compliance Question. I am concerned about recent reports and legal settlements surrounding drug manufacturers' failure to comply fully with the requirements of the MDRP. For example, an analysis by the U.S. Department of Health and Human Services Office of Inspector General found that between 2012 and 2016 taxpayers may have overpaid by as much as $1.3 billion for 10 potentially misclassified drugs. That is why I introduced the Right Rebate Act with Chairman Grassley to prevent drug manufacturers from manipulating Medicaid to increase their profits. However, I continued to be concerned about oversight and manufacturer compliance with the requirements of the Medicaid Drug Rebate Program. Accordingly, please describe the following: your company's current compliance plan and procedures used to ensure compliance with the requirements of the Medicaid Drug Rebate Program including internal audits or other checks you use to identify compliance vulnerabilities; any past or ongoing issues of non-compliance; any corrective actions taken to address identified problems or issues of non-compliance with the MDRP and how such steps were communicated to the Centers for Medicare and Medicaid Services; and any steps taken to improve compliance and ensure that all Medicaid drug rebates owed to the Federal Government and the States are paid in full. Answer. It is Pfizer's policy to comply with all legislation, regulations, provisions, requirements, terms and conditions of the MDRP. In order for its outpatient drugs to be covered by the Medicaid program, a manufacturer must enter into a national rebate agreement with the Secretary of HHS. This agreement generally requires manufacturers to offer Medicaid agencies the mandated discounts for covered prescription drugs. Pfizer is responsible for calculating and reporting to the Federal Government on a monthly and quarterly basis various metrics for each of Pfizer's products and, ultimately, for paying corresponding rebates based on Medicaid recipients' purchases of the company's covered drugs. In return for these rebates, State Medicaid agencies must pay for all of the drug company's covered drugs (with certain limited exceptions). If the price of the manufacturer's drug rises faster than the inflation rate, States may require an additional rebate. Pfizer and/or its predecessor entities have signed a Rebate Agreement with HHS for all Pfizer labeler codes and Pfizer remains vigilant of its obligations under the Medicaid Drug Rebate Program. The Company has robust policies and procedures to ensure compliance with government price calculations, certification and reporting under MDRP including Pfizer's certification, reporting, payment obligations, records retention and audit obligations. The Company's policies and procedures are also meant to impart to Pfizer employees an understanding of the government pricing metrics calculated under the MDRP. Consistent with Pfizer's policies and procedures and available CMS guidance, if Pfizer becomes aware of any instances of non- compliance with the MDRP, Pfizer reports and/or communicates with CMS. Based on our current information and belief, Pfizer complies with CMS regulations and interacts with CMS to take corrective action as instructed. bonus payments tied to specific drugs Question. I am concerned by the potential for employee financial incentives to encourage high launch prices and price increases for prescription drugs. Is your salary, bonus, or other compensation tied to sales or revenue targets of a single product your company sells? Has it ever been? If yes, please state the product or products to which your salary, bonus or other compensation was tied. Answer. No. Dr. Bourla's salary, bonus, or other compensation is not nor has ever been tied to the sales or revenue targets of a single product. Question. Is your salary, bonus, or other compensation tied to either revenue or net income of the company as a whole? Has it ever been? If yes, please explain what assumptions about price increases are used when the compensation committee sets revenue or net income goals. Does the compensation committee provide any guidance to executives in regards to the amount of revenue that the company will generate from price increases versus volume growth? Answer. Dr. Bourla, along with over approximately 48,000 other colleagues, participates in Pfizer's annual bonus plan, Pfizer's Global Performance Plan (GPP), which is funded annually based on Pfizer's performance measured against three financial metrics: revenue, adjusted earnings per share and cash flow from operations and has been since 2008. Therefore, any annual bonuses through Pfizer's GPP, determined by the Compensation Committee of the Board of Directors and ratified by the independent members of the Board, is in part based on company revenue and net income as adjusted earnings per share is derived from net income. In determining Dr. Bourla's bonus, the Compensation Committee also takes into account other factors such as his individual performance against his annual performance objectives and overall company performance (e.g., pipeline). Neither Dr. Bourla's salary nor other compensation is tied to revenue or net income of the company as a whole. In setting the corporate financial goals for compensation purposes, the Compensation Committee uses the company's annual budget as the starting point and it is adjusted accordingly based on the final business plan discussion which accounts for various factors, including access, rebates, losses of exclusivity and expected price adjustments. The Compensation Committee does not provide any guidance with regard to the amount of revenue that the company will generate from price increases versus volume growth. net prices Question. In your testimony, you stated, ``In 2018, the average net price of Pfizer's medicines in the United States declined 1 percent.'' Please describe how the company's year-over-year aggregate net price is calculated. Answer. The Net Sales Price impact versus the Prior Year reflects the year-over-year change in average net selling price (calculated as net sales / units) multiplied by the current year's units. This calculation is performed at a product NDC level, and then aggregated up to the product and then the total business level. The company's aggregate year-over-year impact of price on growth is the summation of the sales price impact versus prior year from all products in dollars, divided by the prior year's total net revenues. In 2018, the year-over-year impact on price on growth for the U.S. pharmaceutical business was negative 1 percent. Question. How many products are included in the calculation of the average net price change? What was the median net price change? Answer. For 2018, there are a total of 399 products included in the U.S. portfolio; median net price impact on growth is negative 4 percent. Question. Is net price weighted? If so, how? For example, in determining the aggregate net price does the company assign different weights to different products based on volume or other factors? Are ``on patent'' and ``off patent'' drugs weighted identically? Are other statistical weights used or are all products treated equally? Answer. Aggregate change in net price is weighted based on product volume (units) and mix. All products--both ``on patent'' and ``off patent''--are treated identically. Question. Does the figure that you provided during your testimony account for U.S. prices, international prices, or both? Generally speaking, when your company reports net price changes, does it differentiate between U.S. and international prices? Answer. The figure of negative 1 percent price impact on growth provided during the testimony is for the United States. Generally speaking, when we respond to inquiries on the impact of price on growth, we have responded on a global basis, a U.S. only basis, or both, dictated by how the inquiry is posed. Question. Please list the five drugs your company sold in the U.S. that had the greatest year-over-year net price increase in 2018, noting the increase for each drug by dollar figure and percentage. Answer. The following products had the greatest positive impact of sales price on growth in the United States in 2018: Prevnar, Lyrica, Chantix, Pristiq, Relpax. Question. Please list the five drugs your company sold in the U.S. that had the lowest year-over-year net price increase (and/or the greatest decrease) in 2018, noting the increase (or decrease) for each drug by dollar figure and percentage. Answer. The following products had the greatest negative impact of sales price on growth in the United States in 2018: Xeljanz, Viagra, Inflectra, Ibrance, Celebrex. Question. For 2018, what was the average net price change in the U.S. market for (1) drugs with no competition, (2) drugs with only branded competition, and (3) drugs with generic competition? Answer. The 2018 impact of price on growth from branded products in the United States was 2 percent. 2018 impact of price on growth from remainder of portfolio (excluding Branded Products) in the United States was negative 5 percent. Question.Pfizer has lost exclusivity for several products in recent years, including Viagra, Zyvox, Relpax, Tygacil, and Pristiq. For each of these products, please provide the percentage and dollar change in the average net price from (1) the last full year in which Pfizer maintained product exclusivity to the (2) first full year in which generic competition was present in the market. Answer. Pfizer has lost exclusivity on several products in recent years, including: 2014: Detrol, Rapamune, Celebrex; 2015: Zyvox; 2016: Relpax, Tygacil; and 2017: Viagra, Pristiq. In all but one case, the net price impact of the branded products listed above was negative the year after exclusivity was lost, reflecting market dynamics and the competitive environment. ______ Questions Submitted by Hon. Robert Menendez Question. During the hearing, when I asked whether your company engaged in tactics to delay generic production of your products, you answered ``no''. However, Pfizer appears on the FDA's list of companies who have access complaints against them. Can you explain the discrepancy between your answer and the FDA list? The FDA list can be found here: https://www.fda.gov/Drugs/DevelopmentApproval Process/HowDrugsareDevelopedandApproved/ApprovalApplications/ Abbreviated NewDrugApplicationANDAGenerics/ucm607738.htm. Answer. As a patient-focused company and leading manufacturer of innovative, generic, and biosimilar medicines, Pfizer supports innovation and a strong, competitive marketplace. Consistent with these values, Pfizer does not block generic manufacturers from purchasing our products, and it has never been our policy to do so. Generic manufacturers are treated the same as any other customer seeking to purchase our products. Pfizer is not aware of any current, unfulfilled requests from a generic manufacturer to purchase a Pfizer product. Generic manufacturers seeking to purchase Pfizer products should request the product from Pfizer's authorized distributors or, if the product is not available at a distributor, from Pfizer directly, the same as any other Pfizer customers. Pfizer's website includes a list of our authorized distributors, from which customers (including generic companies) may purchase most Pfizer products (see https://www. pfizer.com/products/medicine-distributors). For products that are not available via our authorized distributors and that are not in extreme drug shortage or unavailable due to a recall, customers can contact Pfizer's Customer Service center at 1-800-TRY-FIRST (1-800-879-3477) to purchase product directly from Pfizer. The telephone number for Pfizer's Customer Service center is also included on our website at https://www.pfizer.com/contact. Pfizer makes its products available for sale to appropriately licensed entities at Pfizer's listed price and on Pfizer's standard terms of sale. We do not have any agreements with authorized distributors that block the sale of Pfizer's products to generic manufacturers. Regarding the FDA List (the List), while Pfizer supports FDA's (the agency) goal of providing transparency, Pfizer is concerned that the List lacks certain key information and context and, as currently presented, may create the misleading impression that all products on the List are the result of bad faith attempts to block generic manufacturer access to samples. The appearance of a product on the FDA List means only that a generic manufacturer informed the agency at some point in time that it was having difficulty purchasing the listed product. FDA's own disclaimer states that the agency has not independently investigated or confirmed whether a generic manufacturer actually made a request to purchase product, and to whom.\8\ The FDA List also lacks several important pieces of information that would enable a New Drug Application (NDA) holder to investigate its appearance on the List. The List does not include: (1) which generic manufacturer made the request; (2) when and to whom the generic manufacturer made the request (e.g., to a wholesaler, directly to the NDA holder); (3) whether the generic manufacturer that made the inquiry was thereafter able to obtain product; and (4) any reason(s) why a generic manufacturer may not have been able to obtain product (e.g., a recall). Finally, Pfizer notes that FDA does not currently inform an NDA holder in real time when a generic manufacturer notifies the agency that it is having difficulty obtaining product. Had the agency informed Pfizer at the time it received the inquiries noted on the FDA List, Pfizer could have then undertaken its own efforts to resolve the issue. Pfizer communicated its concerns about the FDA List to the agency in May 2018. For your information we have included Pfizer's letter to FDA on this topic and the agency's response (see Exhibits 1 and 2 in the Appendix). --------------------------------------------------------------------------- \8\ (https://www.fda.gov/Drugs/DevelopmentApprovalProcess/ HowDrugsareDevelopedandAp proved/ApprovalApplications/AbbreviatedNewDrugApplicationANDAGenerics/ ucm607738.htm). There are three new drug applications owned by Pfizer on the FDA List: Embeda (NDA 022321), Tikosyn (NDA 020931) and Hemabate (NDA 017989). Embeda offers a good example of the List's shortcomings. Pfizer acquired King Pharmaceuticals (the previous NDA holder of Embeda) in March 2011, and two weeks later determined that Embeda needed to be recalled from the U.S. market due to stability issues. After diligently addressing the issues that led to the recall, Pfizer relaunched Embeda to the U.S. market in January 2015, and it is available for purchase via Pfizer's authorized distributors. However, as a consequence of the recall, Embeda was not available in the U.S. market for almost 4 years which may explain why a generic manufacturer had a problem obtaining it during those years. The FDA List does not specify when the generic manufacturer's inquiry regarding Embeda was made nor does the FDA List indicate that several generic applications for Embeda had been submitted to FDA in 2010 (which means that before the recall, several generic manufacturers were successfully able to purchase Embeda, conduct the necessary testing, and file Abbreviated New Drug Applications (ANDAs)). Pfizer has not identified any recent inquiries from generic manufacturers seeking to purchase Embeda that --------------------------------------------------------------------------- have not been fulfilled. The circumstances around Tikosyn also illustrate the List's shortcomings. Pfizer was able to identify a single inquiry made by a generic manufacturer directly to Pfizer to purchase Tikosyn in 2014. At that time, Tikosyn was subject to an FDA imposed Risk Evaluation and Mitigation Strategies (REMS) with Elements to Assure Safe Use (``ETASU'') that restricted distribution, so Pfizer responded by asking the manufacturer to obtain written confirmation from the FDA that Pfizer's provision of the product to the generic manufacturer would not be considered a violation of its REMS. The generic manufacturer did not contact Pfizer further, and Pfizer never received any written correspondence from the agency. FDA subsequently removed the REMS for Tikosyn in 2016, and multiple generic versions of Tikosyn are now approved, the first generic approval occurring in June 2016. This context is not reflected in FDA's List. Finally, with respect to Hemabate, this product was previously subject to certain restrictions on distribution (i.e., it was sold only to customers with medical and surgical intensive care centers) to ensure its safe and appropriate use. This distribution approach was established by the previous NDA holder (Pharmacia) and it continued following Pfizer's acquisition of Pharmacia in 2003. Pfizer discontinued this approach in early 2018 after determining that it was no longer necessary, and this product is now available through our authorized distributors. During the time when Hemabate was under restricted distribution, it was not available at Pfizer's authorized distributors, but had a generic manufacturer approached Pfizer's Customer Service center directly, we would have been able to address the inquiry. Pfizer's Customer Service was not able to identify any specific requests from a generic manufacturer to purchase Hemabate that have not been fulfilled. We hope that this information explains the apparent discrepancy between Mr. Bourla's testimony and the appearance of these Pfizer products on the FDA List, and demonstrates Pfizer's diligence on these issues and commitment to a competitive marketplace. Question. When new products enter the market, do drug companies set high initial rebates and then provide deep rebates in order to gain access to insurance plan's formularies? Answer. Launch pricing is driven by a multitude of factors, the most important being the medicine's impact on patients and their health. We also may consider other factors like the medicine's potential to reduce other health-care costs, such as hospital stays; the availability of other treatments and generic options; affordability for patients, insurers and governments; and investments to maintain the quality, safety, delivery, and reliability of our medicines. Given the consolidation that has taken place in the U.S. market, the vast majority of retail prescriptions are managed by a few large PBMs. Pharmaceutical manufacturers must successfully negotiate with these PBMs to gain access to their formularies or risk having their products disadvantaged or even excluded from coverage. The system has evolved in a manner where rebates play a significant role in how the PBM business is transacted and in the decisions regarding product placement on formularies. PBMs often win or lose business on the basis of rebate guarantees and are therefore incentivized to favor products with high list prices and deep rebates assuming comparable safety and efficacy. Because the PBMs have enormous leverage and depend on rebates to attract and retain clients, many manufacturers will enter the market with higher list prices and deeper rebates in order to ensure patients have access to their medicines. Question. If CMS finalizes the rebate rule, do you anticipate future products entering the market with significantly lower initial list prices? Answer. Launch pricing will be driven by product value and competitive intensity of the specific therapeutic category. Importantly, if finalized, the rule could result in lower out-of-pocket patient costs at the pharmacy counter and help address the perverse incentives in the system that have been contributing to higher list prices for medicines. ______ Questions Submitted by Hon. Thomas R. Carper Question. What are your recommendations for lowering prices for the 40 percent of drugs that do not offer rebates in Medicare Part D? In the health insurance plans that you offer your employees, do you ask your insurers to pass through the full manufacturer rebates to the beneficiaries? Answer. It is unclear if the 40 percent of drugs that do not offer rebates in Medicare Part D are brand medicines or generics. However, Pfizer pledges to bring more affordable treatment options to the market. Our mid-to late-stage pipeline contains five biosimilar candidates expected to launch in the next 2 to 3 years. Ninety percent of medicines Americans take are generics, and competition from these drugs keeps prices low in most cases. We need to bring similar competition to the biologics market, where some of the most expensive drugs exist. The market today has already seen demonstrated savings as high as 40 percent relative to the branded product. With more competition, we hope even further savings can be realized. Pfizer's plan design is generous and corresponding employee cost sharing for prescription drugs is already very limited--in fact, for many products, Pfizer employees experience no cost sharing at all. Given this, the terms of contract with our PBM for our employee benefits does not include a requirement to pass on rebates to Pfizer employees at the point of sale. Question. The systems for pricing and distributing drugs are opaque and difficult to understand. What are your recommendations for increasing transparency in how your companies set the list prices for drugs, and for improving transparency in the supply chain for prescription drugs? Would you support Federal standards for transparency in setting the list prices for drugs? Answer. Pfizer supports system-wide price transparency that is thoughtful, purpose-driven, and that can result in improved patient care, an enhanced understanding of the comparative value of all medical services, and a more patient-centered use of health-care resources. We would be interested in exploring with the committee ways to ensure transparency across the health care system, including hospitals, plans, PBMs, etc., so that we can make informed judgments about the root of cost inflators in the system. We are also committed to ensuring that patients, health-care professionals and payers understand our commitment to pricing our medicines responsibly. Regarding a Federal transparency standard, we believe that an appropriately crafted, balanced piece of Federal legislation that applies to all stakeholders in the health care system and preempts future State laws could be beneficial for patients. However, Pfizer believes that mandating disclosure of research and development, manufacturing, or marketing costs to assess the value of medicines is inconsistent with purpose-driven transparency. Question. In nearly every sector of the health-care industry, Medicare, Medicaid, employers, and insurers are moving away from fee- for-service payments to reimbursements based on value and performance. Prescription drugs and medical devices were the glaring exceptions to this trend until recently. How many of your drugs are included in value-based contracts and how many patients are benefiting from them? Answer. Patient outcomes should determine our reimbursement and Pfizer pledges that we will aggressively pursue value-based arrangements. We should not be rewarded for treatments that do not work. Currently, Pfizer has value-based contracts for twelve drugs in our portfolio. The agreements are in place with commercial and Medicare payers with millions of covered lives. In addition, Pfizer has a multi-product innovative agreement that has been offered to the majority of States for the Medicaid program, but currently only a small number of States compromising less than five million lives have taken or are actively considering the offer. Question. How do these value-based contracts work to lower drug prices for both patients and taxpayers? Answer. Value-based agreements (VBA) provide a framework for manufacturers to be compensated based on a product's value to patients and the overall health-care system. There are many different types of VBAs but the optimal structure of a VBA includes clinical and/or financial performance metrics for a product. Based on the outcomes achieved, payers use this information to inform how they cover products. Products that perform better should be covered in a more favorable manner which often includes lower out-of-pockets costs for patients which is a benefit to patients in the near term. In the long term, patients can also benefit from other savings either directly, (e.g., reducing spending on other medications, lowering medical costs from reduced hospitalizations, doctor's visits, etc.), or indirectly through lower premiums based on reductions in total cost of care. VBAs can be implemented in Federal and State programs so that the benefits described above can accrue to the Federal programs thereby benefitting taxpayers. Question. Last year, Senator Portman and I did an investigation on the pricing of an opioid overdose reversal drug called EVZIO, manufactured by Kaleo. Kaleo increased the price of EVZIO from $575 in 2014 to $4,100 in 2017. We found that the best price Medicare was able to get for EVZIO, about $4,000, was much higher than the price other Federal programs and private insurers were able to get. It seemed that Kaleo was able to get this higher price of $4,000 from Medicare by helping doctors fill out paperwork showing that the drug was medically necessary, even though there are cheaper alternatives on the market. As a result of the investigation, Kaleo announced it will bring a generic version of the drug to market at only $168 per pack. Are any of your companies providing medical necessity paperwork to doctors in order to get your drugs covered by Medicare? Answer. Consistent with industry practice, Pfizer provides a sample statement of medical necessity and appeals letters through our patient support programs for patients, their caregivers and prescribing physicians to help guide these individuals in gaining access to certain Pfizer medicines after a physician has determined that a Pfizer product is right for a patient and a prescription has been written. These sample letters are generally PDF documents that describe the type of information payers require to approve access/coverage of a particular medication based upon the payers' formulary requirements, such as step therapy (therapeutic agents that must be tried first), proof of diagnosis or other common utilization management techniques that payers determine. Pfizer does not customize these letters, and patients, caregivers and physicians are advised that they are responsible for the accuracy of the information that they submit to the payer to obtain coverage and/or reimbursement. Sample letters are available from Pfizer's third-party call centers which specialize in product access triage with payers, field based reimbursement specialists and Pfizer product websites. Pfizer sales representatives do not provide this information to physicians. Question. In 2017, the Rand Corporation estimated that biosimilar drugs, which are competitors to complex, biologic drugs, could save the United States more than $50 billion over the next decade. Some of you have also argued that increasing the use of biosimilar drugs would help lower drugs costs for consumers and taxpayers. What is delaying the uptake of biosimilar drugs in the United States? What policies do you recommend to increase the development of biosimilar drugs? Answer. Pfizer believes that some of the adverse incentives and barriers to market penetration include: 1. The Rebate Trap: Brand-name biologic companies are using maneuvers to block biosimilar competition such as higher rebates and exclusionary contracts. 2. Misinformation: Some physician and patient-directed materials created by brand companies mischaracterize biosimilars, creating doubt and confusion about the safety and efficacy of biosimilars. As defined by statute, an approved biosimilar must be highly similar to and have no clinically meaningful differences from the reference product and must have the same mechanism of action (to the extent the mechanism(s) of action of the reference product are known) as the reference product; thus, by definition, biosimilars are safe and efficacious treatments relative to the reference product and must work in the same way as the reference product. Any information disseminated by reference product sponsors to suggest or imply otherwise should be promptly addressed by FDA. 3. Need for incentives: Legislative ideas to promote biosimilar uptake could include a shared savings biosimilar model; reduced patient cost sharing for biosimilars. More detail is provided below. Although the biosimilars market in the United States is still relatively new, our experience has been that anticompetitive conduct by brand-name biologic manufacturers, combined with the lack of policy measures to support appropriate uptake of biosimilars, have contributed to a slow uptake. Therefore, we encourage you to consider measures to help incentivize the use of biosimilars, which can substantially lower Medicare costs with demonstrated savings to date as high as nearly 40 percent relative to the branded biologic. Some key policy initiatives we believe will support the uptake of biosimilars in the United States are the following: Waiver of Part B Patient Coinsurance for Biosimilars for a certain period of time:CMS should waive Part B patient coinsurance amounts for biosimilars. Cost-sharing changes could be applied at the HCPCS level. This would not change the overall payment for a biosimilar; however, it would change the beneficiary's payment percentage. CMS should pursue a CMMI model designed to increase access to biosimilars, including a ``shared savings'' model whereby Medicare savings associated with prescribing a biosimilar, as compared to a reference biological, would be shared with providers. CMS should maintain the current biosimilar pass-through status as this provides biosimilars with a ``level playing field'' with their higher priced reference biologic competitors. CMS should create payment incentives for plans by contracting with a measure developer for a biosimilar use measure for the STARS program, which would correct other adverse incentives for biosimilar uptake for Medicare Advantage plans. ______ Questions Submitted by Hon. Benjamin L. Cardin Question. The United States is one of the only countries in the world to allow prescription drug manufacturers to advertise directly to consumers through magazines, billboards, radio, and television commercials. While I will not argue that it is beneficial to educate consumers about an unfamiliar disease and encourage them to seek medical help, most commercials from all of your companies recommend asking about a specific brand name drug, not a medical condition. Furthermore, even if your advertisements follow all FDA rules and list medication side effects, they also almost always list these while a smiling, apparently healthy person is walking on a beach. Researchers say that this type of imagery, combined with viewing hours of drug commercials each month, leads consumers to underestimate the risks associated with medications. For the past decade, studies have shown that aggressive direct-to-consumer advertising is associated with rising drug prices and an increase in inappropriate drug prescriptions. Since researchers have concluded that consumers are misunderstanding the benefits and risks described in your ads, what further policies could help you and your colleagues ensure that you are educating patients in a clear manner? Answer. Pfizer wants patients to have access to our drugs and part of this is making sure patients have the information they need. Pfizer believes that direct-to- consumer (DTC) advertising should be, first and foremost, a tool through which we can provide patients with useful information to inform them about their medical conditions, and the potential benefits and risks of available treatment options so they can have a discussion with their doctors and take an active role in managing their health. The Office of Prescription Drug Promotion at the FDA, which has responsibility for reviewing prescription drug advertising and promotional labeling to ensure that the information contained in them is not false or misleading, studies advertising so that regulations are grounded in evidence on how best to ensure ads are accurate, balanced and not misleading. The FDA's website describes in detail the many ways that its Office of Prescription Drug Promotion ensures that DTC advertising is not misleading.\9\ --------------------------------------------------------------------------- \9\ https://www.fda.gov/aboutfda/centersoffices/ officeofmedicalproductsandtobacco/cder/ucm 090142.htm. DTC advertising is of significant educational importance to patients, especially as the provision of health care becomes more patient-centric. Over the last 2 decades, consumer research sponsored by the industry and the FDA has underscored that clear, relevant communication allows DTC advertising, when executed thoughtfully, to have a positive impact on public health. For example, in 2004, a study by FDA found that ``DTC ads help patients have better discussions with their physicians and provide greater awareness of treatments. The study demonstrated that when a patient asked about a specific drug, 88 percent of the time they had the condition that the drug treated. And 80 percent of physicians believed their patients understood what --------------------------------------------------------------------------- condition the advertised drug treats.'' More recently, according to a 2017 survey, conducted by Princeton Survey Research Associates International on behalf of PhRMA, Americans overwhelmingly reported that DTC advertisements help inform people about new treatments (88 percent), alert people to symptoms that are related to a medical condition they may already have (81 percent), and allow people to be more involved in their health care (79 percent).\10\ Similarly, a research survey published in 2017 with 4,481 U.S. adults and sponsored by a working group of pharmaceutical companies has shown DTC advertising conveys useful information.\11\ DTC ads raise awareness about medications and effectively communicate potential risks and benefits, but they also increase concern about potential side effects. --------------------------------------------------------------------------- \10\ 2017 Direct to Consumer Advertising Survey Results, presented by Princeton Survey Research Associates International, prepared for PhRMA, https://www.phrma.org/report/2017-direct-to-consumer- advertising-survey-results. \11\ DIA, Therapeutic and Regulatory Science, https:// journals.sagepub.com/doi/abs/10.1177/2168479017708226iii, https:// www.fda.gov/AboutFDA/CentersOffices/OfficeofMedicalProducts andTobacco/CDER/ucm090276.htm#Completed. Pfizer believes that PhRMA, individual companies, academics and FDA should continue to study DTC advertising to ensure that pharmaceutical consumer communications are achieving their intended goals to educate, inform information-seeking consumers and facilitate better discussions with health-care professionals. pharmaceutical companies continue to raise prices Question. As you are well aware, high prescription drug prices are the number one concern for Americans and their families. According to the Organization for Economic Cooperation and Development, the average American spends around $1,208 annually on prescription drugs. There have been several instances where brand name or even generic drugs that have been on the market for years continue to increase in price. One of the most well-known examples is Mylan's increase of the price of EpiPen from less than $100 in 2007 to more than $600 in 2016. Another example, is the ever-increasing price of insulin. Sanofi increased the price of a vial of Lantus from $88.20 in 2007 to $307.20 in 2017. And those are just a small sample of price increases. Why don't we see price decreases for drugs that have been on the market for years without new formulations or added benefit? Answer. There are a number of reasons that the price of medicines can change over time. While these reasons often include more obvious changes such as discovery of new indications and new formulations, they can also include less obvious changes such as improvements in the manufacturing and supply chain and market-based factors. Pfizer has reduced the price of many of our older off-patent medicines in the United States, and we are committed to bringing more affordable treatment options to the market to induce competition, including generic and biosimilar medicines. Competition is the best way to promote affordable access to quality, safe and effective medicines; competition means more and better medicines, more options for patients, and more affordable drugs. pay for delay Question. Pay for delay is a tactic that more and more branded drug manufacturers have been using to stifle competition from lower-cost generic manufacturers. This allows you to sidestep competition by offering patent settlements that pay generic companies not to bring lower-cost alternatives to market. These ``pay-for-delay'' patent settlements benefit both brand-name pharmaceutical companies by helping them avoid costly patent litigation and general manufacturers by rewarding them a hefty sum to delay entering the market with a cheaper drug alternative. However, these deals do not benefit consumers. According to an FTC study, these anticompetitive deals cost consumers and taxpayers $3.5 billion in higher drug costs every year. Does your company partake in pay-for-delay settlements? Answer. No. On the contrary, when Pfizer settles patent litigation with generic firms, we do so on terms that generally enable entry of generic competition earlier than the expiration of its patents and that do not involve unlawful reverse payments. Pfizer's patent settlements thus involve lawful compromises that appropriately resolve patent disputes and accelerate patient access to lower cost generics relative to the expiration of its patents. While Pfizer has been the target of plaintiff lawyer driven class action lawsuits challenging certain of its settlements with generic companies, we believe these lawsuits are without merit and are vigorously asserting the pro-competitive nature of these settlements in court. Question. Why would a pharmaceutical company enter into a pay-for- delay agreement? Answer. Pfizer does not enter into these types of settlements and cannot speculate on why others might. Question. Do you think these agreements stifle competition and prevent generic alternatives to your branded medications? Answer. Pfizer's patent settlements do not ``stifle competition'' or ``prevent generic alternatives.'' On the contrary, when Pfizer settles patent litigation with generic firms, it does so on terms that generally enable entry of generic competition earlier than the expiration of its patents and that do not involve unlawful reverse payments. Pfizer's patent settlements thus involve lawful compromises that accelerate patient access to lower cost generics relative to the expiration of its patents. drug rebate rule Question. In January, the Department of Health and Human Services' (HHS) Office of Inspector General (OIG) promulgated a new regulation to remove regulatory safe harbor protections under the Anti-Kickback Statute (AKS) for rebates on prescription drugs rebates paid by manufactures to PBMs under Medicare Part D and for Medicaid managed care organizations (MCOs). The OIG proposal attempts to ban most rebates by eliminating their regulatory protections. The rule is predicted to increase net drug costs in its early years. The CMS actuaries estimate it would cost $196 billion over 10 years. Despite this high price tag, the beneficiary benefits are limited. The proposed rule notes that under the CMS Actuary's analysis, the majority of beneficiaries would see an increase in their total out- of-pocket payments and premium costs; reductions in total cost sharing will exceed total premium increases. I wanted to ask a question about the administration's rebate rule, which I understand that many of the drug manufacturers, and your main trade association, strongly support. According to an analysis of the rule by the Office of Actuaries at CMS, drug manufacturers are likely to initially retain 15 percent of the current rebates as higher net drug prices. Given that estimate, can you provide the committee with any assurances that prices will not increase under this proposed rule? Answer. If finalized, the rule could result in lower out-of-pocket patient costs at the pharmacy counter and help address the perverse incentives in the system that have been contributing to higher list prices for medicines. In 2019, Pfizer expects to pay billions of dollars in rebates to ensure patients with pharmacy benefits coverage in Medicare Part D and patients in commercial plans have access to our medicines. If the proposed rule to share rebates with consumers at the point of sale is finalized, we estimate that seniors taking Pfizer medicines could save $270 on average per year, and up to $574 per year for certain Pfizer medicines, through lower cost sharing. Importantly, we believe any reform should apply to all market segments as this could also lead to further reduction in list prices. A bifurcated market in which we eliminate rebates in government programs but maintain rebates for commercial plans will make it difficult for manufacturers to reduce list prices because a single list price applies to all markets. ______ Questions Submitted by Hon. Sherrod Brown Question. According to an article recently published in the Journal of the American Medical Association, medical marketers spent nearly $30 billion dollars in 2016, up from $17 billion in 1997. Direct-to- Consumer (DTC) advertising had the biggest percentage increase: from $2.1 billion, or 11.9 percent of all medical marketing, in 1997 to $9.6 billion, or 32 percent of total spending, in 2016. Can each of you please provide what your ratio of spending on sales and marketing to research and development is today? Answer. In order to fulfill Pfizer's mission to create breakthrough medicines that change patients' lives, we invest in several areas to ensure an innovative pipeline, top-quality manufacturing, and education of patients and physicians to ensure they have the information they need to make knowledgeable decisions about patient care. In 2018, Pfizer spent approximately $6.9 billion on direct sales and marketing and approximately $8 billion on research and development globally. biosimilars/rebate traps Question. In many of your testimonies, you mention that encouraging the development of generics and biosimilars will help bring down the cost of drugs. However, while 17 biosimilars are now approved in the US, only 7 are actually on the market and available to patients. There are growing concerns about rebate traps, which are ways of gaming the system to ensure a biosimilar is not able to enter the market. Dr. Bourla, in your testimony, you said: ``Adverse incentives that favor higher cost originator biologics are keeping biosimilars from reaching patients. In many cases, payers decline to include lower cost biosimilars or generics in their formularies because they would risk losing the rebates they can get by covering higher cost medicines.'' Your company has filed lawsuits challenging rebate traps as antitrust violations. What do you think should be done about these rebate practices? Answer. Anticompetitive conduct should be stopped through government enforcement of the antitrust laws and in the courts. Brand- name biologic companies should not be permitted to abuse the rebate system to effectively block lower-cost biosimilars from coverage For more details, see Pfizer's Exhibit 4 attached. price-gouging Question. Sanofi, as I understand it, has made a pledge to the public to limit its price increases to the national health expenditures growth projection. Would your company commit to a cap on annual price increases as part of your PhRMA membership criteria? Answer. We are unable to answer this question as it requires analysis under the antitrust laws. Question. What policies would you propose to help ensure lower launch prices for new drugs? Answer. At Pfizer, we are committed to our purpose: breakthroughs that change patients' lives. Pfizer's more than 90,000 colleagues around the world come to work every day focused not only on creating breakthrough medicines, but also on making sure those medicines get into the hands of the patients who need them. The launch prices for our medicines reflect the value that they bring to patients and society. The relationship between the price of a medicine and a patient's out-of-pocket cost is not always clear. Out- of-pocket costs continue to rise due to insurance designs that place a disproportionate burden on consumers who use medicines than other interventions. Consumers on average pay 15 percent of medicine costs but only 2 percent of hospitalization and other health-care costs. We encourage Congress to continue its efforts to understand the complexity of the pricing and reimbursement system in the United States, and to identify ways in which patient out-of-pocket expenditures can be reduced. transparency Question. In many of your testimonies, you mentioned that the current system of pharmacy benefit manager (PBM) back-end rebates do not rarely results in a scenario where the PBM passes on savings to consumers at the point of sale (POS). The administration recently proposed a rule to eliminate the anti-kickback statute safe harbor protections for these drug rebates. Do you agree that greater transparency should be required to understand how manufacturers and PBMs are negotiating prices and rebates to ensure that savings are passed down to beneficiaries? Answer. Pfizer is committed to working toward greater transparency along the supply chain, so patients can better understand what they are paying for and why. We believe pricing transparency policies should seek to inform consumers about the costs of health-care items and services across the industry and should promote a definition of value that considers impact to health and costs over time and across all industry stakeholders. Pfizer believes that the proposed safe harbors lay the groundwork for the systemic change needed to create a simpler, more cost effective, and more transparent U.S. health-care system, and we are committed to operating in this new system. Question. Senator Thune asked if this administration rule would lead you to lowering list prices. Both of you answered that you would be likely to lower your prices. However, if this rule were finalized tomorrow as proposed, would any of your companies be required to lower the list price of any of your drugs? Answer. As long as rebate reform extends to both the commercial market and government programs, there could be a reduction in list prices. The commercial market covers more than 50 percent of Americans with insurance, and the safe harbor will not affect it at all. However, in Medicare, the rebate rule will make list prices less relevant because the entire rebate will be converted to a point of sale discount so that patient out-of-pocket costs, when they are in the deductible, coinsurance, and coverage gap phases of the benefit, will be based off the lower net price. If we ensure that rebates paid out to commercial plans find their way to patients, the patients will see savings of hundreds of dollars. pbms Question. An Axios article from March 7, 2019 highlights the fact that, while ``pharmaceutical companies put a lot of the blame for high drug prices on pharmacy benefit managers,'' many large pharmaceutical companies ``rely on PBMs to manage their own health-care benefits.'' In your role as an employer, does your company contract with a pharmaceutical benefit manager (PBM) to administer the prescription drug benefits for your employees and negotiate lower drug costs on your behalf? Answer. Yes, we contract with a PBM to administer our prescription drug benefits and we work with them to establish criteria for negotiating lower drug costs on our employees' behalf. Question. For those of you who do use a PBM to help manage the prescription drug benefit for your employees, how do you utilize the rebates your PBM negotiates to lower health-care costs or drug costs for your employee plans, and what does your company do with that savings? Specifically, do the savings go toward lowering premiums? Answer. Pfizer's medical and prescription drug coverage is generous in terms of what we subsidize as an employer; therefore we work to ensure that our employees benefit from our investment in our workforce and any savings in the form of affordable plan premiums and substantially lower cost sharing responsibilities for prescription drugs. Question. For those of you who do use a PBM to help manage the prescription drug benefit for your employees, does your PBM offer point-of-sale rebates to your employees? Answer. Pfizer's plan design is generous and corresponding employee cost sharing responsibility for prescription drugs is already very limited--in fact, for many products, Pfizer employees experience no cost sharing at all. Given this, the terms of contract with our PBM for our employee benefits does not include a requirement to pass on rebates to Pfizer employees at the point of sale. ______ Questions Submitted by Hon. Sheldon Whitehouse Question. Please describe any policy changes you support that would result in your company lowering the list prices of its drugs. Answer. Pfizer would support legislation that reforms the current system of rebating to one in which payers are required to use manufacturer provided discounts to ensure that the patient gets the benefit of the discount at the point of sale. We support this reform across all segments of the market where private sector negotiations result in lower net prices including Medicare Part D, Medicaid managed care and the commercial markets. It is important to understand that even if rebates are prohibited, manufacturers will still negotiate discounts with plans consistent with safe harbors in exchange for formulary access, though those discounts will be reflected in lowered drug prices at the pharmacy counter rather than retrospective payments benefitting plans or their PBM instead of the beneficiaries who are underwriting premiums for others. To ensure these benefits reach patients, it will be important for Congress and the administration to ensure that plans do not create new barriers or restrictions that hinder patient access and undermine the spirit of the rule. Question. How much does your company's research and development portfolio rely on taxpayer-funded research conducted by the National Institutes of Health (NIH)? Answer. The biopharmaceutical industry is one of the most research- intensive industries in the United States. In 2017, NIH had a budget of $39.2 billion, only a fraction of which, $3.2 billion, was dedicated to drug discovery. The industry invested over $90 billion in R&D--almost 30 times more. For Pfizer alone, we invested approximately $8 billion in R&D last year. NIH's strength is its focus on important basic scientific research and the industry does derive important insights from basic scientific research conducted by NIH-funded researchers and scientists worldwide. There is, however, a large gap between understanding basic scientific principles and the discovery, development, and delivery of medicines to patients. For example, the initial NIH-funded basic science discovery of cell division and cell signaling proteins in yeast led researchers to identify similar proteins in humans. This early research later informed the thinking of Pfizer scientists and helped pave the way for the discovery and development of targeted cancer drugs like palbociclib, a new treatment for breast cancer. The discovery of cell division in yeast is a long way from discovering and developing a drug that prevents cancer tumors from growing. As stated above, the government plays a role in advancing basic science such as identifying cellular pathways underlying disease. However, the ability to translate knowledge about biological processes into a medicine or vaccine, with appropriate drug-like properties and a clinically meaningful benefit, remains the primary function of the biopharmaceutical industry. The drug discovery and development process involves harnessing existing knowledge of underlying disease biology to chart and execute a research agenda that often encompasses ten to 15 years of discovery research, preclinical testing, clinical development (for dosing, safety, and efficacy) and pharmaceutical science to ensure the quality of the compound to be delivered. Disciplines like medicinal chemistry, process and formulation chemistry and formulation, drug metabolism, pharmacokinetics and safety sciences are practiced at a scale and expertise in the biopharmaceutical industry that extends well beyond government and academic research endeavors to deliver life- savings therapies for patients. Question. How many of your company's products are based, at least in part, on NIH research, and how many are the result of research funded solely by your company? Answer. We have not identified readily available information in response to this request that is maintained in the ordinary course of business. We would need to discuss the scope and terms of this question with your staff to respond appropriately. Question. In each of the last 5 years, how much has your company spent on research and development versus the advertising and marketing of your products? Answer. In order to fulfill Pfizer's mission to create breakthrough medicines that change patients' lives, we invest in several areas to ensure an innovative pipeline, top-quality manufacturing, and education of patients and physicians to ensure they have the information they need to make knowledgeable decisions about patient care. Over the last 5 years, Pfizer spent approximately $34 billion on advertising and marketing and approximately $40 billion on R&D globally. Advertising and marketing expenses include advertising, promotion and field selling. Question. During the hearing, you mentioned that your company would be likely to lower the list prices of its drugs if the recent proposal by the Trump administration to change the current system of rebates was extended to the private market. If the policy was extended to the private market, how large would the list price reductions be relative to the size of the rebates your company is currently providing? Answer. The size of any list price reductions relative to the size of rebates Pfizer is currently providing would depend on all components of the final rule and how the point of sale discount model that replaces rebates will function. Question. How will this proposal affect how your company sets the list prices for new drug products? Answer. At Pfizer, we are committed to our purpose: breakthroughs that change patients' lives. Pfizer's more than 90,000 colleagues around the world come to work every day focused not only on creating breakthrough medicines, but also on making sure those medicines get into the hands of the patients who need them. Launch pricing is driven by a multitude of factors, the most important being the medicine's impact on patients and their health. We also may consider other factors like the medicine's potential to reduce other health-care costs, such as hospital stays; the availability of other treatments and generic options; affordability for patients, insurers and governments; and investments to maintain the quality, safety, delivery and reliability of our medicines. Question. If the proposal is finalized and not extended to the private market, will your company make any list price reductions? If so, how large would the reductions be relative to the size of the rebates your company is currently providing? Answer. Because there is no specific requirement for plans and PBMs to shift away from negotiating contracted rebates in the commercial market, it is possible that a bifurcated market, with the same perverse incentives and the same mechanism to drive list prices higher, will result. If reform does extend to the commercial marketplace, it could result in lowering of list prices. However, we cannot speculate on the amounts until we see the specifics of the rule and the changes that are made to the supply chain. ______ Question Submitted by Hon. Maggie Hassan Question. In June of 2018, the Medicaid and CHIP Payment and Access Commission (MACPAC) unanimously recommended under Recommendation 1.1 in their annual report to Congress that Congress remove the statutory requirement that manufacturers blend the average manufacturer price (AMP) of a brand drug and its authorized generic.\12\ --------------------------------------------------------------------------- \12\ MACPAC: ``Improving Operations of the Medicaid Drug Rebate Program,'' https://www.macpac.gov/wp-content/uploads/2018/06/Improving- Operations-of-the-Medicaid-Drug-Rebate-Program.pdf. This requirement created an unintended loophole. Rather than use the price of the authorized generic, drug companies can sell its authorized generic to a corporate subsidiary at an artificially lower price, and use that lower price to bring down the AMP, which in turn --------------------------------------------------------------------------- lowers the rebate obligation. Does your company engage in this practice? Has your company ever engaged in this practice in the past? Answer. Pfizer has a number of Authorized Generics (AGs) arrangements, both with affiliates and non-affiliates. CMS's Medicaid Covered Outpatient Drugs Final Rule, 81 Fed. Reg. 5170 (Feb. 1, 2016) (the ``Final Rule'') included an extensive discussion of when a primary manufacturer should include or exclude sales of AGs to secondary manufacturers in its average manufacturer price (AMP). Pfizer has developed reasonable assumptions that it believes are consistent with the guidance CMS set forth in the Final Rule for purposes of determining when to include or exclude sales of AGs in its AMP calculation. Pfizer disclosed its assumptions with respect to its approach both in written correspondence and in an onsite meeting with CMS representatives. In addition, Pfizer disclosed its assumptions to the OIG in response to a January 2018 survey. ______ Questions Submitted by Hon. Catherine Cortez Masto Question. According to public filings, in 2015 Pfizer collected U.S. revenues that were more than double the amount you invested in R&D. Is this still true--do you collect more in revenue in the U.S. alone than you invest in R&D? Answer. The biopharmaceutical industry is one of the most research- intensive industries in the United States In 2017, NIH had a budget of $39.2 billion, only a fraction of which, $3.2 billion, was dedicated to drug discovery. The industry invested over $90 billion in R&D--almost 30 times more. For Pfizer alone, we invested approximately $8 billion in R&D last year. Pfizer's number one priority is always the care of our patients, and we are proud of the investments Pfizer makes to insure we continue to bring new, innovative cures to patients. These responsibilities require investments in R&D, manufacturing and other areas to accomplish our mission of creating breakthrough medicines that change people's lives. In 2018, Pfizer spent approximately $20 billion on global R&D and manufacturing. This includes investing in state-of-the-art labs so we can attract the finest scientists in the world and continuing to invest in innovative, high-tech manufacturing to ensure the high quality of our products. Pfizer's revenues in the United States in 2018 totaled approximately $25 billion. Question. As a portion of your revenue, for what percentage of the drugs in your portfolio do you offer no rebates? Based on the drugs in your pipeline, do you foresee that portion growing? For those drugs is your list price equal to your net price? Answer. Approximately one third of Pfizer's revenue comes from products that are not Medicare Part D eligible. This product group includes generics, vaccines, and physician administered products. Of the remaining two thirds of our revenue, 92 percent comes from products that offer Medicare Part D or commercial rebates. The remaining 8 percent is from products that have lost patent exclusivity, have generic alternatives, and offer no rebates. It is not possible to determine at this time whether that portion will increase because rebating on future products will be based on numerous factors, including product value and the competitive intensity of the therapeutic area. For products that do not rebate, there are additional deductions from sales such as prompt payment fees and distribution service fees resulting in the net price being lower than list price. Question. Do you invest more in R&D than you generate in U.S. sales revenue? Please include specific figures. Answer. The biopharmaceutical industry is one of the most research- intensive industries in the United States In 2017, NIH had a budget of $39.2 billion, only a fraction of which, $3.2 billion, was dedicated to drug discovery. The industry invested over $90 billion in R&D--almost 30 times more. For Pfizer alone, we invested approximately $8 billion in R&D last year. Pfizer's number one priority is always the care of our patients, and we are proud of the investments Pfizer makes to insure we continue to bring new, innovative cures to patients. These responsibilities require investments in R&D, manufacturing and other areas to accomplish our mission of creating breakthrough medicines that change people's lives. In 2018, Pfizer's revenues in the United States totaled approximately $25 billion and Pfizer spent approximately $20 billion on global R&D and manufacturing. This includes investing in state-of-the- art labs so we can attract the finest scientists in the world and continuing to invest in innovative, high-tech manufacturing to ensure the high quality of our products. Question. Do you invest more in R&D than you spend on marketing and administration? What company functions do you consider to be included in administration? Please include specific figures. Answer. In order to fulfill Pfizer's mission to create breakthrough medicines that change patients' lives, we invest in several areas to ensure an innovative pipeline, top-quality manufacturing, and education of patients and physicians to ensure they have the information they need to make knowledgeable decisions about patient care. In 2018, Pfizer spent approximately $14 billion on selling, informational and administrative expenses and approximately $8 billion on R&D. Selling, informational and administrative costs are expensed as incurred. Among other things, these expenses include the internal and external costs of marketing, advertising, shipping and handling, information technology and legal defense. Question. Do you invest more in R&D than you spend on marketing and sales? What company functions do you consider to be included in sales? Please include specific figures. Answer. In order to fulfill Pfizer's mission to create breakthrough medicines that change patients' lives, we invest in several areas to ensure an innovative pipeline, top-quality manufacturing, and education of patients and physicians to ensure they have the information they need to make knowledgeable decisions about patient care. In 2018, Pfizer spent approximately $6.9 billion on direct sales & marketing and approximately $8 billion on R&D globally. Direct sales and marketing expenses include, among other things: direct promotion or sale of the company's products. Question. Why do you advertise for the drugs you manufacture? What factors do you consider in choosing which drugs you advertise? Answer. Pfizer believes that direct-to-consumer (DTC) advertising should be, first and foremost, a tool through which we can provide patients with useful information about their medical conditions, the availability of treatments and the potential benefits and risks of available treatment options so they can have a discussion with their doctors and take an active role in managing their health. Research has confirmed that this communication channel delivers on this goal.\13\ --------------------------------------------------------------------------- \13\ See 2017 Direct to Consumer Advertising Survey Results, presented by Princeton Survey Research Associates International, prepared for PhRMA, https://www.phrma.org/report/2017-direct-to- consumer-advertising-survey-results; DIA, Therapeutic and Regulatory Science, https://journals.sagepub.com/doi/abs/10.1177/2168479017708226; https://www.fda.gov/AboutFDA/CentersOffices/ OfficeofMedicalProductsandTobacco/CDER/ucm090276.htm#Completed. We may consider several factors when making decisions about our consumer communications. Some of these may include the information needs of patients who might benefit from one of our medicines and/or the extent to which a health condition is un- and under-diagnosed and --------------------------------------------------------------------------- treated. ______ Pfizer Inc. 500 Arcola Rd. Collegeville, PA 19426 Tel: 484-865-8937 Fax: 484-865-0090 www.pfizer.com Peter Honig, M.D., M.P.H. Senior Vice President Worldwide Safety and Regulatory May 30, 2018 Scott Gottlieb, M.D. Commissioner Food and Drug Administration 10903 New Hampshire Avenue Silver Spring, MD 20993-0002 [email protected] Re: Reference Listed Drug (RLD) Access Inquiries Website and NDA 022321 for Embeda (morphine sulfate; naltrexone hydrochloride) Extended- Release Capsules; NDA 017989 for Hemabate (carboprost tromethamine) Injection; and NDA 020931 for Tikosyn (dofetilide) Capsules Dear Dr. Gottlieb: We write in reference to the newly posted page on the FDA website entitled ``Reference Listed Drug (RLD) Access Inquiries.'' \1\ We note that several new drug applications (NDAs) owned by Pfizer Inc. or wholly-owned subsidiaries of Pfizer (collectively, ``Pfizer'') are included in the list published on this site (``List''): --------------------------------------------------------------------------- \1\ https://www.fda.gov/Drugs/DevelopmentApprovalProcess/ HowDrugsareDevelopedandAp proved/ApprovalApplications/AbbreviatedNewDrugApplicationANDAGenerics/ ucm607738.htm. 1. Embeda (morphine sulfate; naltrexone hydrochloride), NDA 022321; 2. Hemabate (carboprost tromethamine), NDA 01 7989; and 3. Tikosyn (dofetilide), NDA 020931. We write to the Agency for several reasons. First, we wish to inform the Agency about Pfizer's internal practice for handling drug purchasing inquiries from prospective generic applicants, as well as provide some context for why the Agency may have received inquiries about these particular products, and Pfizer's diligence in addressing these issues. We believe that this information demonstrates Pfizer's commitment to supporting innovation and a competitive marketplace. Second, we wish to provide our suggestions on additional, non- confidential information to add to the List in order to provide context critical to understanding the List and its value. Additionally, we wish to express our concerns that the Agency's announcement surrounding the new webpage and how the information is currently presented implies that the companies listed have engaged in ``gaming'' or anti-competitive behavior, which is untrue with respect to Pfizer, and not supported by the facts currently included in the List. Pfizer was surprised and disappointed to discover that FDA had been informed by prospective generic applicants that they had difficulty obtaining some of our products to conduct the testing necessary to support submission of an abbreviated new drug application (ANDA). However, we note that the Agency included a disclaimer on the webpage stating that ``[w]e note that FDA has not independently investigated or confirmed the access limitations described in the inquiries received.'' \2\ As discussed in more detail below, without having any additional information about these inquiries, Pfizer is unable to confirm whether those inquiries were made to Pfizer, and if so, whether they were handled in accordance with Pfizer's practice to make its drug products available to applicants for purchase. --------------------------------------------------------------------------- \2\ https://www.fda.gov/Drugs/DevelopmentApprovalProcess/ HowDrugsareDevelopedandAp proved/ApprovalApplications/AbbreviatedNewDrugApplicationANDAGenerics/ ucm607738.htm. Following publication of the List, Pfizer conducted internal due diligence to identify whether Pfizer was contacted by prospective generic applicants for the listed products, and whether Pfizer was able to provide those customers with the requested drug product. By way of background, our standard approach is to ensure that drug product is available to licensed generic manufacturers at the listed price and on Pfizer's standard terms of sale.\3\ The vast majority of Pfizer's products are available through traditional wholesale channels (i.e., available through one or more of Pfizer's authorized distributors). If Pfizer receives an inquiry about a product that is available at wholesale, Pfizer will refer a prospective buyer to a publicly available list of its authorized distributors, and indicate that the prospective buyer should obtain product from an authorized distributor on that list. For the limited number of products that are not available at wholesale, requests made to Pfizer by a generic manufacturer wishing to purchase drug samples should be fulfilled in accordance with Pfizer's standard practice. If such requests involve a product with a REMS that restricts distribution, Pfizer's position is that a Safety Determination Letter (SDL) needs to be provided prior to sale. Pfizer developed an internal process to handle such requests in early 2015, upon realizing that such requests come into Pfizer via multiple departments and colleagues. --------------------------------------------------------------------------- \3\ If a drug product is in critical short supply, Pfizer will ship products to fulfill orders for dispensing to patients before fulfilling orders for product for testing. --------------------------------------------------------------------------- Tikosyn The List indicated that the Agency had received four inquiries regarding Tikosyn. To the best of its knowledge, Pfizer is aware of only one request for Tikosyn from a prospective generic applicant. At the time of that request, Tikosyn was approved with a REMS with elements to assure safe use (ETASU) that restricted distribution. When contacted by the applicant, Pfizer requested that the applicant provide us with written confirmation from the Agency that Pfizer's sale of the product to the applicant would not be considered a violation of our REMS. The applicant did not contact Pfizer further and Pfizer never received any written correspondence from the Agency. The Agency removed the REMS in 2016, and Pfizer notes that the Access Inquiries Webpage indicates that FDA never issued any SDLs for this drug product. We note despite the inquiries submitted to the Agency identified in the List, ANDAs have been submitted and approved for the drug product. There are three approved ANDAs for the drug product, with the first approved on June 6, 2016,\4\ and two additional ANDAs approved in 2018.\5\ Additionally, the Agency's paragraph IV certification list indicates that the first ANDA containing a paragraph IV certification was submitted on May 1, 2014, when the REMS was still in place.\6\ This additional information indicates that applicants were able to obtain product, submit ANDAs, and obtain approval from the approval even while the REMS was in place. --------------------------------------------------------------------------- \4\ ANDA 207058, see https://www.accessdata.fda.gov/scripts/cder/ ob/results_product.cfm?Ap pl_Type=A&Appl_No=207058, accessed May 23, 2018. \5\ ANDA 208625, see https://www.accessdata.fda.gov/scripts/cder/ ob/results_product.cfm?Ap pl_Type=A&Appl_No=208625, accessed May 23, 2018; ANDA 207746, see https://www. accessdata.fda.gov/scripts/cder/ob/ results_product.cfm?Appl_Type=A&Appl_No=207746, accessed May 23, 2018. \6\ See https://www.fda.gov/downloads/Drugs/ DevelopmentApprovalProcess/HowDrugsareDe velopedandApproved/ApprovalApplications/ AbbreviatedNewDrugApplicationANDAGenerics/UC M293268.pdf. As the REMS has been removed by the Agency, Pfizer now makes Tikosyn available at wholesale through its authorized distributors. Embeda The List indicated that the Agency received one inquiry regarding Embeda. We note that despite the inquiry submitted to the Agency, ANDAs containing a paragraph IV certification were submitted to the Agency for Embeda from May 3, 2010, through May 28, 2010, covering five of the six approved strengths of Embeda.\7\ Pfizer acquired King Pharmaceuticals (and with it, Ernbeda) on March 1, 2011. Two weeks later, Pfizer recalled Embeda from the market due to stability issues with the product. Pfizer spent the next several years diligently addressing the issues that led to the recall, and Pfizer was able to re-launch the product in January 2015. However, as a result of these issues, from March 2011 through January 2015, there was no Embeda product available for sale in the U.S. market. --------------------------------------------------------------------------- \7\ See https://www.fda.gov/downloads/Drugs/ DevelopmentApprovalProcess/HowDrugsareDe velopedandApproved/ApprovalApplications/ AbbreviatedNewDrugApplicationANDAGenerics/UC M293268.pdf. Pfizer was not able to identify any request from a generic applicant to purchase Embeda. Embeda is now available at wholesale through Pfizer's authorized distributors. Hemabate Finally, the List indicated that FDA had received one inquiry for Hemabate, an older drug owned by Pharmacia and Upjohn Co., which was acquired by Pfizer in 2003. Pharmacia, and later Pfizer, limited Hemabate distribution to customers with medical and surgical intensive care facilities to help ensure the drug product was used in accordance with the product's labeling. While this limited distribution may have prevented a prospective generic applicant from acquiring the drug product from a wholesaler, it would not have prevented an applicant from contacting Pfizer directly to buy the drug product. Pfizer ceased the limited distribution of Hemabate to ensure patients and healthcare professionals had appropriate access to the drug product. The product is now available at wholesale through Pfizer's authorized distributors since January 2018. Pfizer was not able to identify any request from a generic applicant to purchase Hemabate. Proposed Revisions to the List We encourage the Agency, in accordance with its goal ``[t]o help address this issue and to provide transparency regarding these inquiries,'' \8\ to add further information to the List. The information Pfizer suggests the Agency include will provide critical context to help clarify to the stakeholders involved, i.e., the American public, the United States Government, and industry, whether an NDA bolder may be preventing generic applicants from obtaining the drug products necessary to support submission of an ANDA Without this information, stakeholders may come away with the false impression that every company on the List has impeded access, as demonstrated by the news coverage of the List and FDA's statements.\9\ --------------------------------------------------------------------------- \8\ https://www.fda.gov/Drugs/DevelopmentApprovalProcess/ HowDrugsareDevelopedandAp proved/ApprovalApplications/AbbreviatedNewDrugApplicationANDAGenerics/ ucm607738.htm. \9\ See, e.g., Sara Koblitz, FDA's Version of the Scarlet Letter, FDA Law Blog (May 23, 2018), http://www.fdalawblog.net/2018/05/fdas- version-of-the-scarlett-letter/; Sheila Kaplan, ``F.D.A. Names and Shames Drug Makers to Encourage Generic Competition,'' The New York Times (May 17, 2018), https://www.nytimes.com/2018/05/17/health/drug- prices-generics-fda.html; Sy Mukherjee, ``The FDA Is Naming and Shaming Companies Accused of Blocking Cheap Generic Drugs,'' Fortune (May 17, 2018), http://fortune.com/2018/05/17/fda-database-generic-drug-delays/. --------------------------------------------------------------------------- We recommend that the List include: The date the inquiry was made to FDA, and if furnished by the prospective generic applicant, the date(s) the applicant attempted to acquire the drug product and failed; If available, whether the prospective generic applicant directly approached the NDA holder or manufacturer , and was unable to obtain product that way; The identity of the NDA holder at the time the inquiry was made; Whether there are approved generic products for the drug product, and when those were approved; Whether and when an applicant submitted an ANDA with paragraph IV certification; and Whether a particular inquiry for a product with a REMS with ETASU restricting distribution included a protocol, and whether the Agency issued an SDL relating to that inquiry. While the Agency includes a disclaimer on the Access Inquiries Webpage that it has not investigated or confirmed the access limitations described in the inquiries it received,\10\ the Agency's statements, both on its website and in public statements, strongly suggest that the Agency endorses the claim that access to biosamples was blocked for all products on the list. In reality, however, the only certain fact about the inquiries on the List is that a prospective applicant complained to FDA that it was unable to obtain the drug product. Neither Pfizer nor the FDA knows whether that is in fact the case, or, if it is, whether there are reasons the applicant did not obtain product that are not the result of ``gaming'' or anti-competitive tactics by NDA holders. For example, the drug may not be available due to a drug shortage, recall (as in the case of Embeda), or because the generic applicant did not actually try all avenues to obtain the drug product, such as contacting the NOA holder or manufacturer directly. --------------------------------------------------------------------------- \10\ https://www.fda.gov/Drugs/DevelopmentApprovalProcess/ HowDrugsareDevelopedandAp proved/ApprovalApplications/AbbreviatedNewDrugApplicationANDAGenerics/ ucm607738. htm. Including this additional information in the List will shed light on the reasons the generic applicant may have been w1able to obtain the drug product, as well as indicate whether generic applicants were able to obtain the drug product, despite the inquiries received by FDA. For example, knowing the dates the inquiries were made could indicate whether the requests came during a time when the drug product was not being marketed, as in a recall situation, or when a REMS with ETASU that restricted distribution was in place that may have triggered the need for a review of the prospective generic applicant's protocol. And, knowing those dates will help industry perform its own due diligence to identify whether a request for drug product was inappropriately denied. Likewise, noting whether the prospective generic applicant stated whether it contacted the NDA holder or manufacturer will indicate whether the applicant reached out to a party that could provide the drug product, and will assist a company in determining whether its policy on providing drug product, such as Pfizer's, was appropriately --------------------------------------------------------------------------- followed. Additionally, providing the identity of the NDA holder at the time of the inquiry will help clarify whether the company that currently owns the NDA could potentially be responsible for the failure to provide drug product, or whether that failure, if any, could be attributable to the prior holder of the NDA. For example, without knowing when the inquiry was made or who the NDA holder was at the time of the inquiry, Pfizer cannot tell for two of its products on the List (Embeda and Hemabate) whether those inquiries came before or after Pfizer's acquisition of the companies that originally owned those products.Accordingly, Pfizer cannot adequately respond to allegations that it may have inappropriately restricted access to its drug products. Including the dates of generic entry would also demonstrate to stakeholders whether generic competition was impeded, or if in fact, one or more generic applicants were able to obtain the product needed in order to obtain approval from the Agency. While we recognize that the Agency may be unable to identify who made the inquiry to FDA, even if that applicant has an ANDA approved later, to the extent that information can be provided, it would demonstrate whether a particular generic applicant was blocked from obtaining product. Additionally, providing more information related to products with REMS that restrict distribution, e.g., whether an applicant has submitted a protocol to the Agency, and whether a particular inquiry on the List correlates to the issuance of an SOL, will also indicate whether the generic applicant who made the inquiry provided its protocol to the Agency, and whether the Agency determined that the protocol contained safety protections comparable to the REMS. Currently, there is no indication as to whether an applicant who complained about not having access to such drug product took appropriate steps to facilitate its access to the product when there was such a REMS in place for the drug product. Finally, we also note that the Agency does not inform an NOA holder in real time when an applicant has had difficulty obtaining product. Given Pfizer's policy to provide drug product when requested, if the Agency had informed Pfizer that it had received such an inquiry on a specific date, Pfizer could have then undertaken its own efforts to resolve the issue. We appreciate the Agency's consideration of the issues raised in this letter, and reiterate our commitment to competition and innovation in the biopharmaceutical industry. Sincerely, Peter Honig, M.D., M.P.H. Senior Vice President, Worldwide Safety and Regulatory cc: Janel Woodcock, M.D., Janet [email protected] Theresa Toigo, [email protected] Kathleen Uhl, M.D., [email protected] Maryll Toufanian, [email protected] ______ U.S. Food and Drug Administration (FDA) July 19, 2018 Peter Honig , M.D., M.P.H. Senior Vice President, Worldwide Safety and Regulatory Pfizer Inc. Email: [email protected] Dear Dr. Honig: Thank you for your letter of May 30, 2018, regarding FDA's Reference Listed Drug (RLD) Access Inquiries webpage. Your letter informs FDA about Pfizer's internal practice for handling inquiries about samples from prospective generic applicants, provides suggestions about additional information to add to the RLD Access Inquiries webpage, and expresses concern about the Agency's announcement surrounding the webpage (Letter at 1-2). The Commissioner referred your letter to the Center for Drug Evaluation and Research (CDER) for response. 1. Pfizer's internal practice for handling drug purchasing inquiries from prospective generic applicants Your letter provides a synopsis of Pfizer's internal practices for handling the inquiries that it receives related to RLD access to its products and the circumstances surrounding the Pfizer products that appear on the RLD Access Inquiries webpage (Letter at 2-3). We appreciate the insight provided by Pfizer on its internal processes. As you are aware, inclusion on the list of products on the RLD Access Inquiries webpage signifies that FDA has received an RLD access inquiry related to limited distribution of the product. As we state on the webpage, FDA has not independently investigated or confirmed the access limitations as described in the inquiries received. You also state that FDA ``does not inform an NDA holder in real time when an applicant has had difficulty obtaining product'' and that ``if [FDA] had informed Pfizer that it had received such an inquiry on a specific date, Pfizer could have then undertaken its own efforts to resolve the issue.'' As the webpage explains (and as also described in the draft guidance for industry How to Obtain a Letter from FDA Stating that Bioequivalence Study Protocols Contain Safety Protections Comparable to Applicable REMS for RLD (How to Obtain a Letter Guidance)), FDA does notify certain RLD sponsors, after the prospective generic applicant has provided appropriate disclosure authorization to the Agency. However, to the extent that Pfizer has a process for prospective generic applicants to obtain samples, we encourage Pfizer to consider making that process public to help ensure both that interested developers know what process to use, and that Pfizer has access to as much information as possible about any access issues. 2. Suggestions for additional information Pfizer believes FDA should add to the RLD Access Inquiries webpage Your letter also contains a list of six points of information Pfizer recommends be added to the RLD Access web page (Letter at 4): 1. The date the inquiry was made to FDA, and (if furnished by the prospective generic applicant), the date(s) the applicant attempted to acquire the product and failed; 2. If available, whether the prospective generic applicant directly approached the NDA bolder or manufacturer, and was unable to obtain product that way; 3. The identity of the NDA holder at the time the inquiry was made; 4. Whether there are approved generic products for the drug product, and when those were approved; 5. Whether and when an applicant submitted an ANDA with a paragraph IV certification; and 6. Whether a particular inquiry for a product with a REMS with ETASU impacting distribution included a protocol, and whether the Agency issued a Safety Determination Letter (SDL) relating to that inquiry. We note that two of these items (``[t]he identity of the NDA holder at the time the inquiry was made,'' and ``whether the Agency issued a [Safety Determination Letter] relating to [an] inquiry'') are already included on the RLD Access Inquiries webpage. The webpage identifies the RLD sponsor associated with each inquiry, and clarifies that this is the RLD sponsor that was listed in the Approved Drug Products with Therapeutic Equivalence Evaluations (the Orange Book) at the time FDA received the inquiry (see footnote on the chart of inquiries). The web page also identifies whether FDA issued a Safety Determination Letter in connection with a particular RLD access inquiry (and explains that receipt of such a letter is preceded by FDA' s review of bioequivalence study protocols to assess whether they contain safety protections comparable to those in the applicable REMS for the RLD). Two of the other points of information (``[w]hether there are approved generic products for the drug product, and when those were approved'' and ``[w]hether an applicant submitted an ANDA with a paragraph IV certification'') are already publicly available on FDA's website (via the Orange Book or Drugs@FDA and the Paragraph IV Certifications List, respectively).\1\ For the remaining points of information, to the extent FDA has access to the information you describe, we will take your feedback (along with feedback from other stakeholders) into account as we consider whether any changes to the RLD Access Inquiries webpage should be made in order to best address and improve transparency about this topic. --------------------------------------------------------------------------- \1\ See http://www.accessdata.fda.gov/scripts/cder/ob/index.cfm, http://www.accessdata.fda. gov/scripts/cder/daf/index.cfm and https://www.fda.gov/downloads/Drugs/ DevelopmentApprovalProcess/HowDrugsareDevelopedandApproved/ ApprovalApplications/Abbre viatedNewDrugApplicationANDAGenerics/UCM293268.pdf, respectively. 3. Concerns relating to the Agency's announcement surrounding the --------------------------------------------------------------------------- RLD Access Inquiries webpage Your letter also indicates that FDA's presentation of information about this topic ``strongly suggest that the Agency endorses the claim that access to biosamples was blocked for all products on the list'' (Letter at 4). As you note, however, the RLD Access webpage makes clear that FDA has not independently investigated or confirmed the access limitations described in the inquiries the Agency received. The webpage is one effort under the FDA's Drug Competition Action Plan to provide transparency about the potential impact of this important issue. If generic companies are unable to purchase the samples they need to support their applications, this slows down, or entirely impedes, the generic drug development process--leading to delays in bringing affordable generic alternatives to patients in need. FDA is committed to advancing policies to help bring more competition to the prescription drug market, and we will continue to consider how we can best advance this goal, including whether any changes to the RLD Access Inquiries webpage should be made. We appreciate your feedback on this issue. Thank you again for contacting us. Sincerely, Janet Woodcock, M.D. Director Center for Drug Evaluation and Research ______ PFIZER FOUNDATION GRANT SUMMARY 2015-2018 TOTAL: $45,877,000 GLOBAL HEALTH PROGRAMMING NOTE: This report includes information for recipient both U.S. and ex- U.S. recipient organizations. Certain Pfizer Foundation grants to non- U.S. grantees are facilitated through U.S.-based donor-advised funds that specialize in vetting and processing grants to non-U.S. grant recipients. IMPROVING HEALTHCARE DELIVERY AND LOCAL INNOVATION ------------------------------------------------------------------------ DATE BOARD APPROVED PARTNER DESCRIPTION AMOUNT ------------------------------------------------------------------------ November 2015 Swasth Global Health Innovation $1,500,000 Foundation, Grants support Afya Research, organizations that are Jacaranda advancing innovative Heath, health models in low Northstar and middle income Alliance, countries. The goal of Penda Health, this portfolio is to World Health improve healthcare Partners, delivery for Clinicas del underserved populations Azucar, and support local Saluno, APOPO, innovation in key Ayzh, Last countries: India, Mile Health, Kenya, Mozambique, LifeNet Mexico, Tanzania, International, India, Liberia, Uganda, One Family Rwanda, and South Health, Africa. The grants Operation ASHA support projects that and Sevamob align to the Foundation's 4 strategic elements: primary healthcare delivery, women and children's health, health technologies for low resource settings and innovative financing mechanisms. The Foundation supported $100,000 grants to fifteen organizations in 10 countries. ------------------------------------------------------------------------ December 2016 Swasth SECOND CYCLE: The 2,000,000 Foundation, Foundation supported Afya Research, $100,000 grants to Jacaranda twenty organizations in Heath, 10 countries. Northstar Alliance, Penda Health, World Health Partners, Clinicas del Azucar, Saluno, Ayzh, Last Mile Health, LifeNet International, One Family Health, Operation ASHA and Sevamob, Purple Source, Unjani, AccuHealth, Bive, Salud Cercana, 2020MicroClini c ------------------------------------------------------------------------ March 2018 Swasth THIRD CYCLE: The 2,000,000 Foundation, Foundation supported Afya Research, $100,000 grants to Jacaranda twenty organizations in Heath, 12 countries. Northstar Alliance, World Health Partners, Clinicas del Azucar, Saluno, Ayzh, Last Mile Health, LifeNet International, One Family Health, Operation ASHA and Sevamob, Purple Source, Unjani, Bive, 2020MicroClini c, MUSO, Possible, UE Life Sciences ------------------------------------------------------------------------ March 2018 Acumen The Foundation provided 500,000 catalytic funding to Acumen America, an early-stage philanthropic venture fund that invests in companies that are improving the lives of low-income Americans and advancing innovative solutions to issues of poverty in America. Through this grant, Acumen will grow its portfolio of health investments that transform services for the poor in the US, including programs that will increase access to care, including lowering the financial and time burden of health and wellness on low-income individuals, improve quality of care to make care more effective, and improve patient experience of care to drive patient engagement & adherence. Portfolio companies include approaches to use technology to address and reduce health disparities for underserved and multicultural populations. ------------------------------------------------------------------------ IMPACT INVESTING CATALYTIC GRANTS ------------------------------------------------------------------------ DATE BOARD APPROVED PARTNER DESCRIPTION AMOUNT ------------------------------------------------------------------------ July 2015 PharmAccess The Foundation provided $1,500,000 a grant to support the development and roll out of PharmAccess' innovative healthcare financing, funding which will help scale PharmAccess's mobile health (mHealth) wallet, a mobile health payment platform linked to M-Pesa in Kenya. The goal of the Foundation's grant is to support user roll- out of the platform and increase the number of people who use the platform, demonstrating its usability and collecting data. The Foundation's grant will target 100,000 low income, urban mothers who will be enrolled and receive a financial subsidy through the mHealth wallet to pay for healthcare services and products for their children under 5 years old. ------------------------------------------------------------------------ July 2015 PATH The Foundation provided 350,000 a grant to support the expansion of PATH's Global Health Innovation Hub in South Africa, in partnership with the South Africa Medical Research Council. The Hub's mission is to accelerate access to the most promising technology innovations by building the capacity of local innovators to develop, manufacture, and deploy global health technologies for vulnerable groups, leveraging PATH's expertise and network in global health and product development. The grant will support activities to build and accelerate local innovations and identify and prioritize local technologies that can deliver global health impact. ------------------------------------------------------------------------ July 2015 UNITUS The Foundation provided 650,000 a grant to support the expansion of `StartHealth,' a health technology jump-starter designed to accelerate the pace of development of bottom of the pyramid focused health- tech startups in India. ------------------------------------------------------------------------ July 2015 Global The Foundation provided 500,000 Partnerships a grant to this impact investment fund, which focuses on providing products and services using market based approaches in Latin America. This includes efforts to pilot and validate high potential health modes for last mile and underserved populations, with a focus on woman and children. ------------------------------------------------------------------------ SUPPORT INNOVATIVE APPROACHES TO ENHANCING NON-COMUNICABLE DISEASE CARE ------------------------------------------------------------------------ DATE BOARD APPROVED PARTNER DESCRIPTION AMOUNT ------------------------------------------------------------------------ November 2015 FHI360 The Foundation provided a $1,000,000 grant to support the ``Suc Khoe Doi Dao'' project that will establish a community- based, integrated NCD prevention and control program in Vietnam. ------------------------------------------------------------------------ November 2015 George This partnership will 1,000,000 Institute of pilot implementation of a Global Health novel primary care platform to support communities and healthcare providers in the prevention and management of NCDs in Indonesia and India. ------------------------------------------------------------------------ April 2016 PATH As part of Pfizer 500,000 Foundation's work to advance oncology care, the Foundation provided support to PATH in Peru to reduce the growing burden of illness and death from breast cancer for underserved populations through early detection linked to service and treatment. ------------------------------------------------------------------------ April 2016 Susan G Komen As part of Pfizer 500,000 Breast Cancer Foundation's work to Foundation advance oncology care, the Foundation provided support to Susan G Komen Breast Cancer Foundation in Northeast Brazil to integrate breast cancer patient support, early detection and timely/ quality diagnosis into existing primary care services with the goal of improving health access and delivery for underserved women. ------------------------------------------------------------------------ April 2016 Partners in As part of Pfizer 500,000 Health Foundation's work to advance oncology care, the Foundation provided support to Partners in Health to increase accessibility of treatment for breast cancer for underserved patients and document and disseminate lessons learned to inform cancer care in Rwanda. ------------------------------------------------------------------------ April 2016 Indiana As part of Pfizer 500,000 University Foundation's work to Center for advance oncology care, Global Health the Foundation partnered with AMPATH, through the Indiana University Center for Global Health, to improve breast cancer services for underserved women in Kenya including screening, early diagnosis, treatment and palliative and survivorship care. ------------------------------------------------------------------------ April 2017 FHI360 The Foundation provided 300,000 additional funding of the ``Abundant Health'' project to support routine prevention, screening and management of hypertension and diabetes care in five commune health stations in Tan Phu district in Ho Chi Minh City, Vietnam. ------------------------------------------------------------------------ April 2017 PATH The Foundation provided 350,000 additional funding of the ``Community Based Program for Breast Health'' project in Peru. ------------------------------------------------------------------------ August 2018 FHI360 The Foundation provided 437,000 additional funding/phase two of the ``Abundant Health'' project to support routine prevention, screening and management of hypertension (HTN) and diabetes (DM) care at the community level. ------------------------------------------------------------------------ August 2018 PATH The Foundation provided 230,000 additional funding of the ``Community Based Program for Breast Health'' project in Peru. ------------------------------------------------------------------------ August 2018 Indiana The Foundation provided 250,000 University additional funding to Center for AMPATH, through the Global Health Indiana University Center for Global Health, to improve breast cancer services for underserved women in Kenya including screening, early diagnosis, treatment and palliative and survivorship care. ------------------------------------------------------------------------ August 2018 George The Foundation additional 150,000 Washington funding to help improve American health outcomes and Cancer reduce health disparities Institute for African-American, Latina and LGBT women. ------------------------------------------------------------------------ PROVIDING CRITICAL SUPPORT FOR PRESSING U.S. PUBLIC HEALTH NEEDS ------------------------------------------------------------------------ DATE BOARD APPROVED PARTNER DESCRIPTION AMOUNT ------------------------------------------------------------------------ April 2016 American As part of Pfizer $1,000,000 Cancer Foundation's work to Society advance oncology care, the Foundation partnered with the American Cancer Society in Los Angeles, California and Hamptons Roads, Virginia to develop a patient navigation model that links community health advisors with federally- qualified health center (FQHC) screening and in- hospital navigation. ------------------------------------------------------------------------ April 2016 George As part of Pfizer 1,000,000 Washington Foundation's work to American advance oncology care, Cancer the Foundation provided Institute support to George Washington University Cancer Institute to help improve health outcomes and reduce health disparities for African- America, Latina and LGBT women. ------------------------------------------------------------------------ December 2017 West Virginia The Foundation provided a 500,000 Department of grant to support opioid Health and addiction prevention and Human education programming in Resources West Virginia. ------------------------------------------------------------------------ December 2017 New Hampshire The Foundation provided a 500,000 Department of grant to support opioid Education addiction prevention and education programming in New Hampshire. ------------------------------------------------------------------------ December 2017 Office of Drug The Foundation provided a 500,000 Control grant to support opioid Policy addiction prevention and education programming in Kentucky. ------------------------------------------------------------------------ December 2017 New Mexico The Foundation provided a 500,000 Department of grant to support opioid Health addiction prevention and education programming in New Mexico. ------------------------------------------------------------------------ December 2017 Utah The Foundation provided a 500,000 Department of grant to support opioid Health addiction prevention and education programming in Utah. ------------------------------------------------------------------------ December 2017 Commonwealth The Foundation provided a 500,000 of grant to support opioid Massachusetts addiction prevention and Department of education programming in Public Health Massachusetts. ------------------------------------------------------------------------ December 2017 Rhode Island The Foundation provided a 500,000 Department of grant to support opioid Health addiction prevention and education programming in Rhode Island. ------------------------------------------------------------------------ December 2017 Foundation for The Foundation provided a 500,000 Appalachian grant to support opioid Ohio addiction prevention and education programming in Ohio. ------------------------------------------------------------------------ December 2017 Department of The Foundation provided a 500,000 Public Health grant to support opioid addiction prevention and education programming in CT. ------------------------------------------------------------------------ December 2017 Delaware The Foundation provided a 500,000 Health and grant to support opioid Social addiction prevention and Services education programming in Delaware. ------------------------------------------------------------------------ ADDRESSING KEY BARRIERS FOR WOMEN AND CHILDREN ------------------------------------------------------------------------ DATE BOARD APPROVED PARTNER DESCRIPTION AMOUNT ------------------------------------------------------------------------ July 2015 Save the The Foundation provided a $500,000 Children grant to support a pilot program offering an integrated approach to delivering immunization and family planning services. The grant supported development of materials and tools for healthcare workers to engage women on family planning services, including formal evaluation. ------------------------------------------------------------------------ November 2015 CARE The Foundation provided a 1,000,000 grant to support increased access to family planning and immunization in Benin by integrating both services into comprehensive delivery and strengthening of clinical skills and outreach. ------------------------------------------------------------------------ November 2015 FHI360 The Foundation provided a 1,000,000 grant to support to develop a global monitoring and evaluation framework to assess task shifting in the delivery of family planning products and demonstrate the effectiveness and safety of using Community Health Workers to administer products. ------------------------------------------------------------------------ November 2015 IRC The Foundation provided a 1,200,000 grant to support increased access to family planning and immunization in Ethiopia and Uganda by integrating both services into comprehensive delivery and male engagement. The project focused on last mile and hard to reach communities. ------------------------------------------------------------------------ November 2015 PSI The Foundation provided a 1,000,000 grant to support increased access to and demand for contraception and reproductive health services in Uganda for women and adolescent girls ------------------------------------------------------------------------ November 2015 U.S. Fund for The Foundation provided a 1,000,000 UNICEF grant to support expanding national mobile health platforms that improve immunization coverage and delivery in Indonesia, Laos and Uganda in partnership with MOH. ------------------------------------------------------------------------ November 2015 World Vision The Foundation provided a 1,000,000 grant to support increased access to family planning and immunization in Kenya by integrating both services into comprehensive delivery, community mobilization and male engagement. ------------------------------------------------------------------------ August 2016 World Vision The Foundation partnered 1,000,000 with World Vision in Zimbabwe to identify gaps in immunization coverage for children, adolescents and adults and support efforts to develop a life course approach to immunization with the Ministry of Health. The focus of the project was to increase access to and use of basic childhood immunizations for children from birth to age 5, and HPV immunization for girls as well as maternal immunizations for pregnant women. In addition World Vision worked with the Ministry of Health to address adult immunization needs, barriers and gaps in community service. Activities included training village health workers, health facility staff and community and faith leaders to educate and mobilize their communities around immunization and promote vaccination. This project also supported the development of a national life course approach. ------------------------------------------------------------------------ August 2016 U.S. Fund for The Foundation provided a 1,000,000 UNICEF grant to help UNICEF improve immunization coverage in urban underserved communities in Asia (Cambodia, Myanmar, Mongolia and the Philippines), and to support UNICEF in conducting operational research to assess the feasibility of using current newborn immunization delivery programs to support life course immunization strategies and reach female populations with additional immunizations and reproductive health services. A centerpiece of this work is supporting the roll out of technology platforms that track immunization coverage and population registries. ------------------------------------------------------------------------ August 2016 UN FOUNDATION The Foundation partnered 1,000,000 with the UN Foundation's Shot@Life program to pilot a life course immunization approach with a focus on rubella. Activities include the development of culturally specific local communication materials on the importance of vaccination and answering concerns parents may have about immunization and life-long impacts, as well as an integrated marketing program featuring social media, digital assets and a U.S.- based media campaign. ------------------------------------------------------------------------ April 2017 IRC The Foundation provided 800,000 additional funding to existing programs in Uganda and Ethiopia to advance integrated immunization and family planning program. ------------------------------------------------------------------------ April 2017 Save the The Foundation provided 250,000 Children additional funding to existing programs in Malawi to advance integrated immunization and family planning program. ------------------------------------------------------------------------ July 2017 CARE The Foundation provided 250,000 additional funding to an existing program in Benin to advance integrated immunization and family planning program. ------------------------------------------------------------------------ July 2017 World Vision The Foundation provided 300,000 additional funding to an existing program in Kenya focused on integrated immunization and family planning. ------------------------------------------------------------------------ March 2018 CARE The Foundation provided 1,000,000 additional funding to support work in Benin, where mortality of mothers and children is high. The project works in 20 public health clinics to increase the uptake of two live saving interventions, childhood vaccinations and family planning, through integration of the two services. The project addresses two main challenges at the same time: a weak healthcare system and sociocultural barriers in the community, which both need to be overcome for women and children to have access to quality health services. ------------------------------------------------------------------------ March 2018 IRC The Foundation provided 1,500,000 additional funding to permit the IRC to expand their work with health partners in Ethiopia and Uganda to increase the use of immunization and family planning by reaching women with information and services at a critical time--the 12 months following birth. ------------------------------------------------------------------------ March 2018 Save the The Foundation provided 1,000,000 Children additional funding to an existing program in Malawi to advance integrated immunization and family planning program with Save the Children. ------------------------------------------------------------------------ March 2018 World Vision The Foundation provided 1,000,000 funding for the second phase of this project, Increasing Use of Family Planning (FP) and Immunization Services in Kenya. ------------------------------------------------------------------------ DISASTER RELIEF RESPONSE ------------------------------------------------------------------------ DATE BOARD APPROVED PARTNER DESCRIPTION AMOUNT ------------------------------------------------------------------------ April 2015 American Red Cross Cyclone Pam $10,000 ------------------------------------------------------------------------ June 2016 American Red Cross West Virginia 25,000 relief efforts ------------------------------------------------------------------------ June 2016 American Red Cross Ecuador Earthquake 75,000 ------------------------------------------------------------------------ June 2016 International Ecuador Earthquake 75,000 Medical Corp. ------------------------------------------------------------------------ Sept-Oct 2016 American Red Cross West Virginia 25,000 relief efforts ------------------------------------------------------------------------ Sept-Oct 2016 American Red Cross Ecuador Earthquake 75,000 ------------------------------------------------------------------------ Sept-Oct 2016 International Ecuador Earthquake 75,000 Medical Corp. ------------------------------------------------------------------------ Sept-Oct 2016 American Red Cross Louisiana flooding 25,000 ------------------------------------------------------------------------ Sept-Oct 2016 Direct Relief Louisiana flooding 25,000 International ------------------------------------------------------------------------ Sept-Oct 2016 One SC Fund Hurricane Matthew 50,000 in SC ------------------------------------------------------------------------ Sept-Oct 2016 Direct Relief Hurricane Matthew 50,000 International in the US ------------------------------------------------------------------------ Sept-Oct 2016 Project Hope Hurricane Matthew 50,000 in Haiti ------------------------------------------------------------------------ Sept-Oct 2016 World Vision Hurricane Matthew 50,000 in Haiti ------------------------------------------------------------------------ Sept-Oct 2016 PSI Zika virus relief 100,000 efforts ------------------------------------------------------------------------ Sept-Oct 2016 The CDC Foundation Zika virus relief 500,000 efforts ------------------------------------------------------------------------ Sept-Oct 2016 The CDC Foundation Zika virus relief 500,000 efforts ------------------------------------------------------------------------ Sept-Oct 2016 PAHO Foundation Zika virus relief 1,000,000 efforts ------------------------------------------------------------------------ Sept-Oct 2016 Florida State Dept Zika virus relief 1,000,000 of Health efforts ------------------------------------------------------------------------ Sept-Oct 2016 Texas Dept of Zika virus relief 1,000,000 Health efforts ------------------------------------------------------------------------ December 2016 American Red Cross Louisiana flooding 25,000 ------------------------------------------------------------------------ December 2016 Pinebelt Foundation Mississippi 25,000 flooding ------------------------------------------------------------------------ December 2016 American Red Cross Peru and Colombia 100,000 mudslide ------------------------------------------------------------------------ December 2016 UNICEF Peru and Colombia 100,000 mudslide ------------------------------------------------------------------------ Sept-Oct 2017 Americares Hurricane Harvey-- 125,000 TX and LA ------------------------------------------------------------------------ Sept-Oct 2017 World Vision Hurricane Harvey-- 125,000 TX and LA ------------------------------------------------------------------------ Sept-Oct 2017 American Red Cross Hurricane Harvey-- 250,000 TX and LA ------------------------------------------------------------------------ Sept-Oct 2017 One America Appeal Hurricane Irma--TX 500,000 and FL ------------------------------------------------------------------------ Sept-Oct 2017 American Red Cross Hurricane Irma-- 400,000 Puerto Rico/U.S. Virgin Islands ------------------------------------------------------------------------ Sept-Oct 2017 IFRC Hurricane Irma-- 100,000 Caribbean ------------------------------------------------------------------------ Sept-Oct 2017 American Red Cross Hurricane Maria-- 250,000 Puerto Rico ------------------------------------------------------------------------ Sept-Oct 2017 American Red Cross Mexico Earthquake 250,000 ------------------------------------------------------------------------ Sept-Oct 2017 UNICEF Mexico Earthquake 250,000 ------------------------------------------------------------------------ Sept-Oct 2018 American Red Cross California 50,000 Wildfires ------------------------------------------------------------------------ Sept-Oct 2018 United Way of North Hurricane Florence 100,000 Carolina ------------------------------------------------------------------------ Sept-Oct 2018 Central Carolina Hurricane Florence 100,000 Community Foundation ------------------------------------------------------------------------ Sept-Oct 2018 International Hurricane Florence 200,000 Medical Corp. ------------------------------------------------------------------------ Sept-Oct 2018 American Red Cross Hurricane Florence 100,000 ------------------------------------------------------------------------ Sept-Oct 2018 International Hurricane Michael 100,000 Medical Corp. ------------------------------------------------------------------------ Sept-Oct 2018 Florida Disaster Hurricane Michael 100,000 Fund ------------------------------------------------------------------------ Sept-Oct 2018 Save the Children Indonesia Tsunami 100,000 ------------------------------------------------------------------------ Sept-Oct 2018 Direct Relief Indonesia Tsunami 100,000 International ------------------------------------------------------------------------ Sept-Oct 2018 World Vision Indonesia Tsunami 100,000 ------------------------------------------------------------------------ Sept-Oct 2018 Physicians for a California 100,000 Healthy California Wildfires ------------------------------------------------------------------------ ______ UNITED STATES DISTRICT COURT EASTERN DISTRICT OF PENNSYLVANIA PFIZER INC., Plaintiff, Case No. v. JURY TRIAL DEMANDED JOHNSON & JOHNSON and JANSSEN BIOTECH, INC., Defendants. COMPLAINT For its Complaint, plaintiff Pfizer Inc. (``Pfizer'') alleges against defendants Johnson & Johnson and Janssen Biotech, Inc. (collectively, ``J&J''), as follows: PRELIMINARY STATEMENT 1. It is accepted national policy to promote price competition among pharmaceutical manufacturers after an originator firm's patent protection has expired. This policy extends to biologics, a unique category of medications that are derived from living organisms. As one lawmaker put it when adopting applicable legislation, such competition ``is good for patient safety, consumer choice . . . and the healthcare system at large.'' This case is about J&J's efforts to suppress that competition and deprive society of those benefits by, among other things, imposing a web of exclusionary contracts on both health insurers and healthcare providers (e.g., hospitals and clinics) to maintain its stranglehold in respect of an important biologic, brand named Remicade, also known by its generic name, infliximab. 2. For many patients suffering from chronic diseases such as rheumatoid arthritis, plaque psoriasis, and Crohn's disease, the best-- and sometimes the only--option for treatment is infusion therapy with infliximab. As these conditions are chronic in nature, patients often require long-term treatment and multiple infusions per year. 3. J&J owned patents protecting infliximab and has been amply rewarded for its invention: Between 1998 and 2016, Remicade was the only infliximab product on the market. This position allowed Remicade to become J&J's best-selling drug by far, generating about $4.8 billion in U.S. sales in 2016 alone. In fact, Remicade is among the best selling drugs in the world. For most uses, at list price Remicade sells for about $4,000 per infused dose and about $26,000 for a full year of treatment. When Pfizer introduced its competing biologic Inflectra (infliximab-dyyb) in 2016, J&J deployed improper exclusionary tactics to maintain the dominance of its flagship product. 4. Inflectra received marketing approval under the Biologics Price Competition and Innovation Act (``BPCIA''). Congress recognized the growing importance of biologics, as well as the growing costs associated with them, and passed the BPCIA in 2010. The purpose of the BPCIA, as its name suggests, is to foster meaningful price competition for long-entrenched branded biologic products--with the ultimate goal of lowering healthcare costs. To facilitate price competition, the BPCIA provides an abbreviated FDA approval pathway for ``biosimilar'' versions of branded biologic drugs. Biosimilars are products that the FDA has determined to have ``no clinically meaningful differences'' from the already approved biologic (sometimes referred to as the ``reference listed drug'' or ``RLD'') in terms of safety, purity, and potency. Although the BPCIA was enacted in 2010, FDA procedures for implementing the Act did not become effective until a few years later, and biosimilars are only recently beginning to come onto the market, with the first biosimilar approval in 2015. 5. On April 5, 2016, Inflectra received FDA approval as the first biosimilar to Remicade. Pfizer began shipping Inflectra in November 2016 and set its initial list price, often referred to as the wholesale acquisition cost (or ``WAC''), at 15 percent below the then-current WAC of Remicade.\1\ --------------------------------------------------------------------------- \1\ WAC is the manufacturer's published list price to wholesalers or direct purchasers, not including prompt pay or other discounts, rebates, or reductions in price. 6. The threat from Inflectra did not go unnoticed by J&J. Within weeks of Inflectra's launch, J&J began to deploy what it publicly has termed its ``Biosimilar Readiness Plan.'' The core features of the plan are exclusionary contracts that foreclose Pfizer's access to an overwhelming share of consumers, coupled with anticompetitive bundling and coercive rebate policies designed to block both insurers from reimbursing, and hospitals and clinics from purchasing, Inflectra or --------------------------------------------------------------------------- other biosimilars of Remicade despite their lower pricing. 7. J&J's actions with respect to Remicade exclude competition at multiple levels: 8. Exclusive contracts with insurance company payers. Insurer decisions regarding reimbursement policies have a dramatic impact on which infliximab product will be stocked by healthcare providers such as hospitals and clinics. Because providers administer infliximab on site (it is an infusion product), they must use their own funds to stock the product, purchasing it for later use and relying upon subsequent reimbursement from insurers to recoup their expenses. Given the cost of biologic drugs generally, and Remicade in particular, there is almost no chance that providers will pay for a product that is not widely covered by insurers for fear of stocking a product that will not be reimbursed after the provider administers it to a patient, as even a single unreimbursed dose may cost the provider in excess of $4,000. Recognizing this, J&J has induced insurers to enter into contracts that require an explicit commitment not to cover Inflectra at all or to do so only in the rarest of circumstances--in effect, to make Remicade the only covered infliximab. As a direct result of these exclusive dealing contractual commitments, Inflectra is either not listed on the insurance company's medical policy--a published listing of the drugs approved for reimbursement under the insurer's medical benefit--or is designated reimbursable only in so-called ``fail first'' cases. The ``fail first'' exception, which requires that Remicade has been tried by and failed with respect to a given patient before a biosimilar infliximab can be reimbursed, is medically inappropriate and illusory in practice. If Remicade, which is an infliximab product, does not work for a patient, a physician would turn to a non-infliximab drug, not to Inflectra, which also is an infliximab product and has no clinically meaningful differences from Remicade. The spurious nature of J&J's ``fail first'' restriction is illustrated by the fact that in early 2017, before J&J's contracts took hold, the major insurers listed Inflectra at parity with Remicade--indicating that they saw no medical reason to favor one over the other. J&J's ``fail first'' contractual restrictions therefore have the same practical effect as pure exclusive contracts: both operate to exclude Inflectra from qualifying for reimbursement under the insurers' plans; both prevent the insurer from freely reimbursing for Inflectra or another biosimilar without breaching the contracts; and both foreclose Inflectra from competing for patients covered by those plans. J&J has entered into such contracts with all or nearly all national health insurance companies. These ``biosimilar-exclusion'' contracts, on their own, have foreclosed Inflectra's ability to vie for at least 70 percent of commercially insured patients in the United States, including a significant number of commercially insured patients who reside in the Philadelphia area. But the foreclosure effects of those insurer contracts go well beyond the immediate impact on patients covered by the affected plans, as discussed below. 9. Exclusionary rebates and bundling arrangements with insurance company payers. A key to J&J's ability to coerce insurers into accepting its exclusionary commitments is its denial of rebates to insurers that decline J&J's exclusivity commitments, thereby imposing a substantial financial penalty. In effect, J&J says to insurers, ``If you want to receive attractive rebates on Remicade for all your existing Remicade patients''--rebates which, for some insurers, run into the tens of millions of dollars annually--``you must agree to not reimburse for Inflectra, or to do so in the most limited of circumstances.'' In short, insurers that decline J&J's offer face a substantial financial penalty, and those that accept receive a payoff (multimillion dollar rebate payments) in return for their commitment to exclude biosimilars. J&J's threatened financial penalty is effective because there is a substantial base of patients across the country who are already controlling their diseases with Remicade and thus are unlikely to switch to a lower-priced biosimilar once available. Although biosimilars have no clinically meaningful differences in safety, purity, and potency from the biologic originator, they are not substitutable without the prescriber's approval (unlike generics for non-biologic drugs approved under the Hatch-Waxman structure, which are substitutable without a new prescription). And, although the FDA's approval permits physicians to switch from the originator to the biosimilar, and Pfizer believes they should consider doing so in appropriate circumstances, as a practical matter, existing-patient Remicade demand is economically incontestable, that is, not a realistic candidate for biosimilar firms to compete for. As the head of J&J's pharmaceuticals business told investors, ``the 70 percent of patients who are [already] stable on Remicade are highly unlikely to switch.'' \2\ J&J bundles this economically ``incontestable'' demand for Remicade with the portion of demand that is ``contestable'' for biosimilar firms-- new patients starting therapy with infliximab--by threatening to deny rebates on all Remicade prescriptions if any infliximab biosimilar prescriptions are reimbursed, effectively meaning insurers would have to forfeit their rebates and pay J&J's ever increasing price for the incontestable patients. --------------------------------------------------------------------------- \2\ Johnson & Johnson, Q3 2016 Results Earnings Call Transcript (Oct. 14, 2016), available at https://seekingalpha.com/search/ transcripts?term=johnson+%26+Johnson+biosimilar. J&J also bundles rebates on multiple different products, such that insurers that refuse to grant exclusivity to Remicade would be forced to pay higher prices and/or forego enhanced portfolio rebates. The net effect of these anticompetitive bundling practices is that the insurers subject to them have no real choice but to agree to J&J's exclusivity conditions. Insurers have made it clear to Pfizerthat its net cost for Inflectrawould need to be low enough to offset the loss of J&J rebates. Pfizer and other biosimilar firms cannot feasibly make up the difference for the J&J rebates (on the existing Remicade patient base) that insurers would lose if they declined J&J's conditions. Insurers have stated a desire to support biosimilars--and the lower per-unit prices they bring--but realistically cannot do so without incurring a substantial financial penalty imposed by J&J and thus potentially placing themselves at a disadvantage relative to insurers --------------------------------------------------------------------------- accepting J&J's rebates. 10. J&J-engineered coverage restrictions impact provider purchasing behavior and thus magnify foreclosure. The foreclosure created by J&J's exclusionary insurer-level contracts goes well beyond the patients covered by these health insurers: Inflectra's coverage status has a spillover effect on the purchasing decisions of healthcare providers (as noted, the clinics, hospitals, and other institutions that purchase and administer infliximab) as well as the prescribing decisions of physicians affiliatedtherewith. Given the widespread gaps in Inflectra's insurance coverage--engineered by J&J--providers have overwhelmingly chosen to stock only Remicade (which is essentially universally covered given its long tenure and dominant position) rather than deal with the risk of possible denials of coverage for Inflectra. Thus, providers have declined to purchase Inflectra across the board, even for patients covered by insurance plans that do cover the product. To take one example, even though Inflectra is covered by Medicare and other government programs, providers have been unwilling to stock Inflectra even for potential use with such government-insured patients. As a result, not only is the federal government forced to continue reimbursing for Remicade, the more expensive product, but the effective foreclosure of biosimilars is expanded well beyond the 70 percent of commercially insured patients directly foreclosed by J&J's insurer contracts. Indeed, as of September 1, 2017, about 90 percent of healthcare provider accounts using infliximab had purchased no Inflectra at all. J&J has stoked providers' reluctance to purchase Inflectra by touting with providers the very lack of coverage for Inflectra created by J&J's own exclusionary contracts. 11. Exclusionary rebates and bundling arrangements with healthcare providers. Beyond the spillover impact described above, J&J has also extended its practices of multi-product bundling and bundling of contestable and incontestable demand in contracts with healthcare providers. 12. J&J's exclusionary plan has been remarkably effective at stifling competition: Today, almost no national commercial health insurer provides coverage for Inflectra (except under the spurious ``fail first'' scenario), and the vast bulk of healthcare provider accounts using infliximab (approximately 90 percent) have not purchased Inflectra at all. Despite some coverage by regional and government plans, Inflectra has secured less than 4 percent of total infliximab unit sales in the U.S. as of September 1, 2017. 13. The harm to Pfizer and to competition as a whole--and, ultimately, to consumers, businesses, and the U.S. government, who bear the brunt of rising healthcare costs nationwide--is manifest. In response to a new entrant offering lower prices for a product deemed to have ``no clinically meaningful differences'' from the incumbent's brand, basic economics would predict that market-wide prices would fall. Instead, the opposite has occurred. Since the time the FDA approved Inflectra and J&J implemented its publicly-stated plan to block biosimilars like Inflectra, J&J has raised the list price of Remicade by close to 9 percent and increased the amount the U.S. government reimburses for Remicade by more than $190 per infused dose. J&J's list price increases are not overcome by increased rebates and discounts: Remicade's ``average selling price'' (``ASP'')--which by federal law is an average of a drug's pricing after taking into account discounts, rebates, and other price concessions--actually has increased since Inflectra's entry. As of September 2017, Remicade's ASP was more than 10 percent higher than Inflectra's ASP. Pfizer has offered to guarantee clients that Inflectra would be less expensive unit-for-unit than Remicade during a contract term. Despite Inflectra's lower per- unit prices, and J&J's escalating prices, Remicade has not lost any substantial volume or share of sales to Inflectra, even though FDA determined there to be no clinically meaningful differences between the two products. 14. In July, J&J extolled the success of its scheme, noting that it had not ``seen much of an impact'' from Inflectra's entrance, and that J&J is ``especially well- prepared to manage through the Remicade biosimilars.'' \3\ J&J also said it was confident that it could fend off even subsequent biosimilar entrants this year because of its exclusionary contracts: ``[W]e have our contracting in place with all the managed care organizations [e.g., health insurers].'' \4\ The net result is that patients (along with healthcare providers and the U.S. Government) have fewer choices and pay more than they should. --------------------------------------------------------------------------- \3\ Johnson & Johnson, Q2 2017 Results Earnings Call Transcript (July 18, 2017), available at https://seekingalpha.com/search/ transcripts?term=johnson+$26+Johnson+biosimilar. \4\ Id. 15. Major stakeholders at every level of the healthcare marketplace --------------------------------------------------------------------------- are suffering as a result of J&J's competition-reducing actions: Most importantly, consumers suffer in the form of artificially inflated prices (including higher coinsurance payments, insurance premiums, and taxes), as well as reduced choice. Government programs, including Medicare--and ultimately taxpayers--suffer by having to pay artificially higher prices for the vast majority of their infliximab utilization. Pfizer, of course, suffers loss of sales, investment, and reputation as a result of J&J's success in securing commitments to disadvantage Inflectra. 16. Pfizer brings this action under the antitrust laws of the United States to challenge J&J's anticompetitive conduct. If J&J's conduct is allowed to continue, its ``Biosimilar Readiness Plan'' will become the playbook for biologic originator firms seeking to preserve their dominance in the face of biosimilar competition--thus subverting the competition-enhancing objectives of the BPCIA. 17. Allegations relating to Pfizer's conduct are based on personal knowledge; other allegations are based on Pfizer's research, publicly available sources, feedback from customers, and information and belief. THE PARTIES 18. Plaintiff Pfizer is a corporation organized and existing under the laws of Delaware. Pfizer's principal place of business in the United States is located at 235 East 42nd Street, New York, New York 10017. Pfizer is a research-based international pharmaceutical company which researches, develops, manufactures, and sells pharmaceutical products across the spectrum, from branded innovator products to generics and over-the-counter medications. Pfizer is also committed to developing biosimilar medications to bring competition, lower prices, and choice to patients. 19. Pfizer has commercialized Inflectra, a biosimilar to J&J's Remicade, through its partnership with Celltrion, the holder of the drug product's Biologics License Application. The FDA approved Inflectraas a biosimilar to Remicade on April 5, 2016. 20. Defendant Johnson & Johnson is a corporation organized and existing under the laws of New Jersey. Johnson & Johnson's principal place of business in the United States is located at One J&J Plaza, New Brunswick, New Jersey 08933. Johnson & Johnson is an international pharmaceutical company--one of the largest in the world--and was the sole supplier of infliximab, marketed as Remicade, between 1998 and 2016, when Inflectra came to market. 21. Defendant Janssen Biotech, Inc. (``Janssen'') is a wholly owned subsidiary of Johnson & Johnson. Janssen is a corporation organized and existing under the laws of Pennsylvania. Janssen's corporate headquarters are located at 800 Ridgeview Drive, Horsham, Pennsylvania 19044. Janssen co-owns or has licenses to the Remicade patents and performs the marketing for Remicade in the United States. JURISDICTION, VENUE, AND INTERSTATE COMMERCE 22. This action arises under the antitrust laws of the United States, including Section 1 of the Sherman Act, 15 U.S.C. Sec. 1, Section 2 of the Sherman Act, 15 U.S.C. Sec. 2, Section 3 of the Clayton Act, 15 U.S.C. Sec. 14, and Sections 4 and 16 of the Clayton Act, 15 U.S.C. Sec. Sec. 15 and 26. 23. Subject matter jurisdiction is founded on 28 U.S.C. Sec. Sec. 1331 and 1337(a). 24. Johnson & Johnson may be found, transacts business, and is subject to personal jurisdiction in this judicial district. 25. Janssen maybe found, transacts business, and is subject to personal jurisdiction in this judicial district. 26. The violations of law alleged in this Complaint took place, in part, in this judicial district and have injured Pfizer in this district. Venue is therefore appropriate in the Eastern District of Pennsylvania under Section 12 of the Clayton Act, 15 U.S.C. Sec. 22, and under 28 U.S.C. Sec. Sec. 1391(b) and (c). 27. The creation, marketing, sale, and distribution of Remicade and Inflectra, and the actions complained of in this Complaint, occur in and substantially affect interstate commerce. FACTUAL AND REGULATORY BACKGROUND A. Biologics 28. Biologics are treatments derived from living systems such as microorganisms or plant or animal cells. As the FDA explains: ``Biological products include a wide range of products such as vaccines, blood and blood components, allergenics, somatic cells, gene therapy, tissues, and recombinant therapeutic proteins. Biologics can be composed of sugars, proteins, or nucleic acids or complex combinations of these substances, or maybe living entities such as cells and tissues. Biologics are isolated from a variety of natural sources--human, animal, or microorganism--and may be produced by biotechnology methods and other cutting-edge technologies. Gene-based and cellular biologics, for example, often are at the forefront of biomedical research, and may be used to treat a variety of medical conditions for which no other treatments are available.'' \5\ In contrast to most drugs, which are chemically synthesized and whose structure is known, most biologics are complex mixtures that are not easily identified or characterized.\6\ --------------------------------------------------------------------------- \5\ See U.S. Food & Drug Administration, What Are ``Biologics'' Questions and Answers, https://www.fda.gov/aboutfda/centersoffices/ officeofmedicalproductsandtobacco/cber/ucm133077.htm (last visited Sept. 18, 2017). \6\ Id. B. Congress Enacts the Biologics Price Competition and --------------------------------------------------------------------------- Innovation Act to Spur Price Competition for Biologic Medications 29. Congress has made clear that competition in pharmaceuticals is to be encouraged, and, to that end, in 1984 enacted the Hatch-Waxman Act (``Hatch-Waxman''), which established an abbreviated pathway for approval of generic counterparts to non-biologic branded drug products. Before Hatch-Waxman, a generic applicant had to conduct the same kinds of safety and efficacy studies (including large clinical trials and the like) as the originating drug manufacturer. Such a process, which can cost hundreds of millions of dollars and take years to complete, was prohibitive for would-be generic entrants and led to the near absence of generic competition to branded drug products. Hatch-Waxman eliminated this hurdle; it allowed generic firms to rely upon the originator's safety and efficacy studies. Generic applicants need only show that their products use the same active pharmaceutical ingredient as the originator, and that their products are bioequivalent (e.g., that the generic product's uptake into the body is equivalent to the branded drug). A principal goal of Hatch-Waxman was to trigger price competition with originator products, many of which had enjoyed longstanding exclusivity. That goal has been achieved: According to the FDA, the competition spurred by Hatch-Waxman has saved more than $1.6 trillion for patients and the healthcare system.\7\ --------------------------------------------------------------------------- \7\ See Kathleen ``Cook'' Uhl, 2016: A Record-Setting Year for Generic Drugs, U.S. Food & Drug Administration (Feb. 24, 2017), available at https://blogs.fda.gov/fdavoice/index.php/2017/02/2016-a- record-setting-year-for-generic-drugs/ (noting that ``2016 was a record-setting year for FDA's generic drug program,'' and that ``[o]ver the last 10 years, generic drugs have saved the U.S. healthcare system about $1.68 trillion''). 30. However, for a number of reasons, biologic products generally are not covered by the Hatch-Waxman procedures. Nevertheless, given the success of Hatch- Waxman in spurring competition for non-biologic medicines, Congress and nearly all stakeholders in the healthcare system have recognized the great desirability of having an analogous system for biologics.\8\ --------------------------------------------------------------------------- \8\ See U.S. Food & Drug Administration, Implementation of the Biologics Price Competition and Innovation Act of 2009 (Feb. 12, 2016), available at https://www.fda.gov/drugs/ guidancecomplianceregulatoryinformation/ucm215089.htm (``The goal of the BPCI Act is similar, in concept, to that of the Drug Price Competition and Patent Term Restoration Act of 1984 (a.k.a. the `Hatch- Waxman Act') which created abbreviated pathways for the approval of drug products under Federal Food, Drug, and Cosmetic Act (FFD&C Act).''). 31. In 2009, Congress addressed the need for competition in the biologics marketplace by introducing the BPCIA, which was signed into law in 2010. The Act furthers the ``FDA's longstanding policy of permitting appropriate reliance on what is already known about a drug, thereby saving time and resources and avoiding unnecessary duplication of . . . testing.'' \9\ --------------------------------------------------------------------------- \9\ U.S. Food & Drug Administration, Implementation of the Biologics Competition and Innovation Act of 2009, https://www.fda.gov/ Drugs/GuidanceComplianceRegulatoryInformation/ucm215089.htm (last visited Sept. 18, 2017). 32. A principal purpose of the Act--as reflected in its very name (i.e., the Biologics Price Competition and Innovation Act)--was to spur --------------------------------------------------------------------------- price competition in biologic drug products: ``We have to find a way to introduce competition into [the biosimilar] market,'' including balancing ``giving incentives for development of new products but bringing about the benefits of competition in the marketplace.'' (Hon. Henry Waxman, United States Representative from California) ``Legislation to facilitate the development of biosimilars should promote competition and lower prices[.]'' (Hon. Anna G. Eshoo, United States Representative from California) ``We want to foster a robust biosimilar market.'' (Hon. Joe Barton, United States Representative from Texas) ``[C]ompetition [from biosimilars] is good for patient safety, consumer choice, and drive[s] savings for consumers and the healthcare system at large.'' (Hon. Gene Green, United States Representative from Texas) 33. The BPCIA provides an abbreviated regulatory approval pathway for the introduction of biosimilars. A biosimilar applicant may rely on the clinical studies of the reference listed drug if it can show: (a) that the proposed biosimilar is ``highly similar to the [originator product, or RLD] notwithstanding minor differences in clinically inactive components''; and (b) that ``there are no clinically meaningful differences between the [proposed biosimilar] and the [RLD] in terms of safety, purity, and potency'' (42 U.S.C. Sec. 262(i)(2)). 34. Although biosimilars have no clinically meaningful differences in safety, purity, and potency from the RLD, they are not automatically substitutable with the RLD (unlike Hatch-Waxman generics). Thus, if a doctor prescribes the RLD, a pharmacist cannot substitute a biosimilar unless that product has been designated as interchangeable by FDA and the relevant state law permits substitution of interchangeable biologics.\10\ This allows originator firms to retain the bulk of their existing patient bases, which typically is not possible for a branded firm to do when a Hatch-Waxman generic enters (because state substitution laws permit prescriptions for the brand to be automatically substituted with the Hatch-Waxman generic by the pharmacist without the need for physician intervention). This difference enables biologic originator firms to leverage their monopolies over existing patients to extract anticompetitive commitments from insurers and providers. --------------------------------------------------------------------------- \10\ The BPCIA does provide for an ``interchangeable'' designation, but FDA published draft guidelines for establishing interchangeability only this year. U.S. Food and Drug Administration, Considerations in Demonstrating Interchangeability With a Reference Product (Draft Guidance) (Jan. 17, 2017). And while Pfizer believes that Inflectra can be safely and effectively substituted for Remicade (indeed, studies have shown that switching patients can be done safely and effectively, and Pfizer has supported and/or taken part in some of these studies), it will be years before Inflectra or any other biologic receives a formal ``interchangeability'' designation from FDA in the United States. Nonetheless, neither the BPCIA nor FDA contemplates that biosimilars should be prevented from competing in themarketplace--i.e., that consumers should be denied access to them--until they are designated interchangeable. --------------------------------------------------------------------------- C. Infliximab 35. Infliximab is a tumor necrosis factor (``TNF'')-inhibiting biologic drug used to treat a range of immune-mediated diseases, including Crohn's disease, ulcerative colitis, rheumatoid arthritis, psoriatic arthritis, ankylosingspondylitis, and plaque psoriasis. 36. As a biologic, infliximab is not synthesized in a laboratory, but rather derived from a living organism. Infliximab is a chimeric IgG1k monoclonal antibody (composed of human constant and murine variable regions) specific for human tumor necrosis factor-alpha. Infliximab is produced by a recombinant cell line cultured by continuous perfusion and is purified by a series of steps that includes measures to inactivate and remove viruses. 37. Infliximab is an infusion therapy, meaning it is administered intravenously. Thus, infliximab patients must (in most cases) visit clinics, hospitals, or other medical facilities to receive the therapy from healthcare professionals. As a result, patients rarely purchase infliximab themselves at retail pharmacies. Instead, infusion centers, clinics, and hospitals purchase infliximab, and after administration, seek reimbursement from the patient's insurer or a government payer (e.g., Medicare). Infliximab is an important medicine that has provided life-changing benefits to millions of patients. D. J&J's Remicade 38. J&J introduced the first infliximab product in the United States in 1998, under the brand name Remicade. 39. Remicade is widely used: An estimated 475,000 patients in the U.S. receive at least one dose of Remicade annually. This fact, combined with the cost (approximately $4,000 per infused dose at list price), makes administering Remicade a major expense item for insurers and healthcare providers. 40. J&J's list price increases for Remicade and other pricing actions have resulted in consistent increases in Remicade's ASP. J&J has increased the price of Remicade without experiencing a loss of sales to other therapies. Instead, Remicade sales have increased steadily since it was introduced. Indeed, J&J has been able to continue raising the price of Remicade notwithstanding the arrival of Inflectra. 41. Since 1998, J&J has made billions of dollars in profit on Remicade. E. Pfizer's Inflectra 42. Beginning in 2008, Celltrion undertook to develop a biosimilar to Remicade and move it through the intensive FDA review process. The Biologics License Application for Inflectra was filed with FDA in 2014. After rigorous scientific review, FDA approved infliximab-dyybon April 5, 2016. In the FDA news release announcing its approval of Inflectra, the director of FDA's Center for Drug Evaluation and Research reiterated that approval as a biosimilar reflects a determination of ``no clinically meaningful differences'' from the originator, and stated that ``[p]atients and the health care community can be confident that biosimilar products are high quality and meet the agency's rigorous scientific standards.'' \11\ --------------------------------------------------------------------------- \11\ See U.S. Food and Drug Administration, FDA Approves Inflectra, A Biosimilar to Remicade (Apr. 5, 2016), https://www.fda.gov/ newsevents/newsroom/pressannouncements/ucm494227. htm. 43. J&J claimed patent protection over Remicade--as noted, making it the sole provider of infliximab for nearly two decades--and thus Pfizer and Celltrion were forced to defend against J&J's patent suit in parallel with FDA's regulatory review of the Inflectra application. On August 17, 2016, J&J's patent covering the infliximab antibody was ruled invalid by the United States District Court for the District of Massachusetts, a ruling which confirmed that J&J had no valid right to exclude Pfizer (or other potential biosimilar entrants). The Court held that the antibodies covered by J&J's Remicade patent had been disclosed and claimed in an earlier patent.\12\ Just a few months after the district court ruling, the U.S. Patent and Trademark Office issued a final decision in a re-examination of the same patent, holding that the patent was invalid.\13\ --------------------------------------------------------------------------- \12\ Janelle Lawrence, J&J Remicade Patent Found Invalid in U.S. Victory for Pfizer, Bloomberg (Aug. 17, 2016), https:// www.bloomberg.com/news/articles/2016-08-17/j-j-patent-on-remicade- expiring-in-2018-invalid-judge-rules. \13\ Id. 44. After overcoming these hurdles, and after a 180-day notice period required by the BPCIA, Pfizer began selling Inflectra in --------------------------------------------------------------------------- November 2016. 45. Inflectra is approved for all the same indications as Remicade, except pediatric ulcerative colitis, as to which J&J continues to enjoy an FDA-granted period of exclusivity because of the indication's status as an ``orphan'' indication (established on proof that the number of people affected by the disease or condition for which the drug is to be developed is fewer than 200,000 persons), which is scheduled to end in 2018. On that date, Inflectra will be eligible to seek approval for pediatric ulcerative colitis. In any event, this indication accounted for less than 5 percent of overall infliximab utilization in 2016. 46. Pfizer introduced Inflectra with a list price 15 percent lower than Remicade's, and, in negotiations with insurers and providers, offered substantial additional pricing concessions in the form of discounts and/or rebates that in some instances were more than 40 percent below Inflectra's list price. The goal and effect was to offer Inflectra for less than J&J was offering Remicade; indeed, for many customers, Pfizer committed to ensure that Inflectra would have a lower net per-unit price than Remicade. 47. Given that it was charging a lower price for Inflectra than J&J was charging for Remicade, Pfizer was optimistic that it would have an opportunity to compete, to secure a reasonable share of the business, particularly for new patients, and to bring the benefits of price competition to consumers, providers, insurers, and the U.S. government. However, due to J&J's exclusionary conduct, competition has been foreclosed. J&J maintains its monopoly and has continued to capture over 96 percent of infliximab sales even while maintaining prices far above competitive levels. F. The Importance of Insurance Coverage for Infliximab 48. Most patients who are prescribed Remicade have some form of insurance coverage or qualify for patient assistance. The sources of insurance coverage are (a) private insurance, accounting for about 60 percent of patients nationally, and (b) government insurance programs (principally Medicare and Medicaid), accounting for the remaining 40 percent. Insurance coverage and reimbursement are therefore key to the adoption of the product by patients and healthcare providers alike. If a product as expensive as Remicade is not widely reimbursed, it will not be significantly utilized. 49. Because Remicade is not dispensed in a retail pharmacy but rather administered intravenously in a clinic or other institutional setting, it generally is not included under the ``pharmacy benefit'' of most health plans. In the pharmacy benefit setting, physicians prescribe a drug and the patient procures the medication him or herself at the pharmacy, paying for it with a combination of insurance coverage (either private or government-sponsored) and out-of-pocket payment (usually, a co-pay). In the pharmacy benefit context, neither the prescribing physician nor the institution with which the physician is affiliated bears financial risk with respect to the drug selected, i.e., the drug is not purchased and stocked in advance by providers at their own cost. The pharmacy buys the drug, dispenses it, and is reimbursed. 50. In contrast, ``medical benefit'' products such as Remicade are administered at a clinic or other healthcare provider site, and the provider itself first purchases the drug product for use in the infusion treatment of patients, and then later seeks reimbursement for the drug from a third party payer (a practice commonly referred to as ``buy and bill''). When a treatment is administered, the provider must secure payment for the service, including the cost of the product dispensed (which the provider had to pay up front with its own funds). In this context, the provider has a strong interest in utilizing drugs that are widely covered by insurance, particularly by the major national commercial health insurers and significant regional insurers active in its area. If a drug product is not widely covered, such that there is a risk that coverage might be denied, and providers thus would be burdened with a potential financial loss for what they paid for the product, providers are much less likely to purchase that product--a response that is in line with the providers' economic interests (to be reimbursed). 51. Many of the facilities administering infusion services of the type at issue here are physician-owned. Thus, the physicians themselves have both prescribing authority and a strong financial incentive to avoid products that are not widely covered. 52. Commercial insurers typically publish medical policies enumerating the drug products they will cover under the medical benefit and the terms under which they will do so. For example, medical policies may exclude drugs from coverage, or they may dictate restrictions on use. Drug manufacturers compete, usually with rebates or other price concessions, to obtain coverage under insurer medical policies and to have either fewer restrictions on reimbursement than their competitors--or, at a minimum, to achieve ``parity'' whereby the competing products have the same restrictions on reimbursement and the patient and/or doctor can choose between them. Securing at least parity placement is critical, especially for new products seeking to gain traction in the marketplace, and particularly with large insurers, which have tens of millions of covered patients. G. The Importance of Access at the Provider Level 53. As discussed above, providers (hospitals, clinics, etc.) are the market actors that actually purchase infliximab for use with their infusion services for patients. J&J's agreements and conduct have the effect of foreclosing this essential source of distribution. 54. Providers do not want to risk being unable to secure reimbursement for any drug used to treat a patient after having already paid for the product. Because it can be costly to monitor coverage status across myriad insurers and implement procedures to match product use to a patient's coverage, gaps in reimbursement policies give ``buy and bill'' provider accounts reasons to stock only products with universal (or near-universal) coverage. Here, due to J&J's anticompetitive contracts at the insurer level, J&J has succeeded in preventing biosimilar competitors from achieving the same status. J&J'S EXCLUSIONARY SCHEME 55. Not content with its nearly 2 full decades of exclusivity with Remicade, and the billions of dollars of profits that such exclusivity enabled, J&J hatched a multifaceted scheme to ensure that biosimilars would never become viable competitors--a scheme embodied, at least in part, in its ``Biosimilar Readiness Plan.'' J&J revealed the existence of the plan, and at least some specifics thereof, during a recent investor call and presentation.\14\ And a J&J consultant bragged at a recent health conference that his firm helped design the plan to realize J&J's goal of ensuring that biosimilars never gain a foothold. --------------------------------------------------------------------------- \14\ Johnson & Johnson, Q3 2016 Results Earnings Call Transcript (Oct. 14, 2016), available at https://seekingalpha.com/search/ transcripts?term=johnson+%26+Johnson+biosimilar. 56. J&J's conduct has not gone unnoticed in the industry. For example, an analyst at a prominent securities firm (Bernstein Research) recently summarized key aspects of J&J's scheme, observing that J&J has: (a) ``negotiated with [insurers]'' and set up ``exclusive contracts . . . in nearly half the market,'' thereby making providers unwilling to purchase Inflectra; (b) ``offered up deeper discounts to large independent infusion centers [i.e., major providers], which are more economically sensitive''; and (c) ``bundled several drugs and medical devices [together] for larger hospitals.'' \15\ The analyst also noted that a key to J&J's strategy was the ``long `tail' of [patients] remaining on the brand'' \16\--the incontestable demand-- which gives J&J leverage to extract commitments from insurers not to cover Inflectra.\17\ Another industry observer, commenting on the Bernstein survey, noted that J&J's ``fail first'' requirements with insurers ``force hospitals and clinics to buy Remicade.'' The observer also noted that: --------------------------------------------------------------------------- \15\ Aaron Gal, Biosimilars: So, Why Has Remicade Biosimilar Not Gotten Much Traction in the U.S., Bernstein Research, at 1 (July 20, 2017). \16\ Id. \17\ While the Bernstein survey suggests that Pfizer has offered only a `` `low single digit' discount off of the ASP'' of Inflectra, that is not accurate. As set forth herein, Pfizer has offered Inflectra at a significantdiscount (to list price as well as ASP), but continues to be foreclosed by J&J's anticompetitive contracts. J&J, meanwhile, has raised the price of Remicade since Inflectra's entry. The Bernstein survey also speculates that with the entry of a third biosimilar in mid-2019, ``we would likely [sic] see one of the biosimilars crossing the Rubicon and offering the required discounts.'' Gal, supra note 15, at 1. However, as set forth herein, J&J's exclusive contracts and bundling practices foreclose all new biosimilar entrants, including Pfizer, from competing with Remicade on price and, if not stopped, will allow J&J to continue to maintain the monopoly power it currently exercises with Remicade. J&J has had yet another advantage--an ability and willingness to bundle different medicines as part of a package deal. By offering discounts and rebates for several drugs, J&J can secure contracts and crowd out rivals. And discounts are also appealing to physicians who run their own infusion centers.\18\ --------------------------------------------------------------------------- \18\ Ed Silverman, J&J Now Has Two Competitors for A Pricey Blockbuster. Will That Finally Drive Down Prices?, Stat News (July 25, 2017), https://www.statnews.com/pharmalot/2017/07/25/merck-samsung- biosimilar-pfizer-johnson/. --------------------------------------------------------------------------- 57. J&J's scheme is set forth in more detail below: A. J&J Bars Access to Insurer Reimbursement Through Improper Exclusive Contracts and Anticompetitive Bundling Practices 1. J&J's Exclusive Contracts with Health Insurers 58. A centerpiece of J&J's strategy to block competition from biosimilars has been to secure contractual commitments from commercial insurance companies to exclude biosimilars from coverage under their plans, making Remicade the exclusive infliximab available to patients covered by those plans. Such contractual commitments have taken various forms. Some insurers have entered into contracts with J&J that required them simply to exclude biosimilars from their medical policies and/or drug formularies altogether. Other J&J contracts have imposed a spurious requirement that the biosimilar could be reimbursed only after a patient first tried and failed on Remicade (the ``fail first'' requirement), which virtually ensures that the biosimilar will never be prescribed and never be reimbursed. If a patient fails on Remicade, it would defy sound medical judgment for a physician to switch to the therapeutically equivalent biosimilar, which works in exactly the same way, rather than another therapy, to which a patient may potentially respond differently.\19\ Regardless of their specific form, these contracts all had the same effect--to exclude biosimilars from coverage and (as one analyst recently confirmed) grant an ``exclusive'' to Remicade.\20\ --------------------------------------------------------------------------- \19\ The notion that attempting treatment with a biosimilar after its reference listed drug has first failed would defy medical judgment recently has been reinforced in the European League Against Rheumatism rheumatoid arthritis management recommendations. In those recommendations, ``[t]he Task Force reiterated its position that if a TNF-inhibitor fails, another TNF-inhibitor--but not a biosimilar of the same molecule!--can be as effective as changing the mode of action.'' Smolen, J.S., et al., EULAR Recommendations for the Management of Rheumatoid Arthritis with Synthetic and Biological Disease-Modifying Antirheumatic Drugs: 2016 Update, Annals of the Rheumatic Diseases 2017:0:1-18 (Mar. 6, 2017). \20\ Gal, supra note 15, at 1. 59. J&J has induced most major health insurers, covering at least 70 percent of commercially insured patients in the United States, to adopt these improper contractual exclusivity restrictions and to impose outright bans on Inflectra's coverage or so-called ``fail first'' requirements. These insurers include (in decreasing order of patients --------------------------------------------------------------------------- covered): National insurers: (a) UnitedHealthcare: UnitedHealthcare adopted the ``fail first'' requirement. United Healthcare has approximately 30.6 million covered commercial medical patients across all 50 states. (b) Anthem: Anthem excluded Inflectra from coverage altogether. Anthem has approximately 30.4 million covered commercial medical patients concentrated in 14 states. (c) Aetna: Aetna adopted a complex set of indication specific conditions which operate in practice as ``fail first'' requirements. Aetna has approximately 17.9 million covered commercial medical patients in all or nearly all states and territories in the United States. (d) Cigna: Cigna adopted the ``fail first'' requirement. Cigna has approximately 13 million covered commercial medical patients across all 50 states. Regional insurers: (a) HealthNet (Centene): HealthNet adopted a complex set of indication specific conditions which operate in practice as ``fail first'' requirements. HealthNet (as part of its acquisition by Centene) has approximately 12 million covered commercial medical patients concentrated in 28 states. (b) CareFirst/Blue Cross Blue Shield: CareFirst adopted the ``fail first'' requirement. Indeed, CareFirst agreed with J&J that Inflectra would be non-preferred, meaning it cannot be reimbursed unless there are ``clinical circumstances that would exclude the use of . . . preferred products,'' including Remicade. CareFirst has approximately 3.2 million covered commercial medical patients principally found in Maryland, Virginia, and the District of Columbia. (c) Blue Cross Blue Shield of North Carolina: BCBS of North Carolina adopted the ``fail first'' requirement. BCBS of North Carolina has approximately 2.7 million covered commercial medical patients concentrated in North Carolina. (d) Blue Cross Blue Shield of Tennessee: BCBS of Tennessee adopted the ``fail first'' requirement. BCBS of Tennessee has approximately 1.6 million covered commercial medical patients concentrated in Tennessee. (e) Blue Cross Blue Shield of Louisiana: BCBS of Louisiana adopted the ``fail first'' requirement. BCBS of Louisiana has approximately 1.6 million covered commercial medical patients principally concentrated in Louisiana. (f) Excellus Blue Cross Blue Shield: Excellus BCBS adopted the ``fail first'' requirement. Excellus has approximately 1.2 million covered commercial medical patients concentrated in New York. (g) Independence Blue Cross: Independence Blue Cross adopted the ``fail first'' requirement. Independence Blue Cross is the leading health insurer in Philadelphia. These contracts alone affect approximately 114 million covered commercial medical patients of the over approximately 214 million patients covered by commercial medical insurance in the United States. Pfizer has reason to believe there are more. 60. While exclusive contracts can--in certain circumstances--be perfectly appropriate, the exclusivity provisions described in Paragraphs 8, 9, and 58 serve no legitimate or procompetitive purpose and were not earned through simple price competition. After Inflectra's FDA approval in April 2016, and before J&J implemented its exclusionary contracts, health insurers undertook reviews to determine whether there was a medical reason not to reimburse Inflectra or to disfavor it relative to other therapies. Following these reviews, several major health insurance companies--including at least Aetna, Anthem, and UnitedHealthcare-- classified Inflectra at parity with Remicade. This confirmed that there was no medical reason justifying a restrictive reimbursement policy toward Inflectra. It also meant that, for the time being, Inflectra would be reimbursed without restriction. As a result, the stage was set for Inflectra to begin competing head-to-head with Remicade on a level playing field--and for patients to begin receiving the benefits of greater choice and lower prices. 61. But this initial state of affairs was short lived. As a result of J&J's anticompetitive conduct, insurers began to reverse course and restrict coverage of Inflectra. 62. For example, in October 2016, UnitedHealthcare, the nation's largest health insurer, with over 30 million covered commercial medical patients, published an update to its medical and site of care policies classifying Inflectra at parity with Remicade for the approved indications (with an effective date of November 1, 2016). This meant that, for UnitedHealthcare, Inflectra would be reimbursed freely and would not be disfavored relative to Remicade. Just weeks later, however, UnitedHealthcare reversed course. UnitedHealthcare classified Remicade as its ``preferred'' product, and instructed that Inflectra would be eligible for reimbursement only in circumstances so limited as to be practically non-existent. Under UnitedHealthcare's new policy, Inflectra could be reimbursed only where the following conditions are met: (a) the patient must show a minimal clinical response, or an intolerance or adverse reaction, to Remicade; (b) the physician must attest that Inflectra would not lead to the same adverse responses; and (c) the patient must show no loss of favorable response in established maintenance therapy with Remicade, and must not have developed neutralizing antibodies to any infliximab biosimilar product that has made the therapy less effective. As a practical matter, this meant that Inflectra would not be reimbursed for UnitedHealthcare's more than 30 million commercial medical members, and that Remicade would be the exclusive infliximab with UnitedHealthcare--despite the lack of any medical basis for denying those members access to a lower-priced alternative to Remicade. 63. UnitedHealthcare's reversal, of course, did not happen by chance. J&J induced UnitedHealthcare to enter into an exclusive deal by threatening to penalize UnitedHealthcare with the loss of significant rebates unless UnitedHealthcare agreed to deny coverage of Inflectra. 64. J&J has employed the same approach to secure exclusive deals with most or all of the major insurers identified above. In most cases these coercive biosimilar-exclusion contracts were the only economically viable option for insurers--as adopting any alternative would require the insurer to incur a substantial penalty (i.e., foregone rebates to existing Remicade patients) that could not be offset by the per-unit cost savings available on the number of patients likely to use the biosimilar, at least in the near term. 2. J&J's Bundling Tactics with Health Insurers 65. J&J's threatened penalties are effective because they leverage the large base of existing patients already stabilized on Remicade. Given that J&J has offered the only infliximab option in the United States for nearly two decades, its base of existing Remicade patients is substantial, amounting to hundreds of thousands of patients across the country. And, in part driven by J&J's marketing efforts to secure this outcome, existing Remicade patients are likely to stay on Remicade. Thus, the demand for Remicade associated with this existing base of patients is, as a practical and economic matter, incontestable. This is so despite the fact that switching is within the scope of FDA's approval for use of biosimilars and thus appropriate when medically directed--something Pfizer discusses with clients. The situation is different for new patients who may be candidates for infliximab. In light of this, Pfizer has focused, among other things, on competing for a substantial share of new patient starts (the ``contestable'' demand) by pricing Inflectra competitively with both insurers and providers on a unit-for-unit basis. The fact that Inflectra's ASP is lower than Remicade's underscores the cost savings it offers. 66. By threatening to withhold attractive rebates on all Remicade prescriptions-- including those for existing patients as well as new ones--unless an insurer agrees to exclusivity, J&J is able to leverage the incontestable demand for Remicade to exclude competition for the contestable demand, i.e., it bundles the contestable and incontestable demand. Even if Pfizer offers a significantly lower price for Inflectra unit-for-unit, as it has done, insurers will agree to J&J's exclusive deals to avoid losing rebates on the substantial base of existing Remicade patients who are not likely to switch to Inflectra despite the presence of the lower-priced biosimilar. A recent article by two Yale Medical School professors in the Journal of the American Medical Association illustrates how the kind of leverage J&J has over existing, stable Remicade patients allows it to extract commitments to exclude the biosimilar: If a biosimilar manufacturer intends to upend the preferred position of the brand by offering a substantial price discount to the [insurer], the branded manufacturer can respond by withdrawing the rebate on the [branded] biologic, creating a ``rebate trap.'' For any patient continuing the [branded] biologic, a payer's cost for that patient will double once the rebate is withdrawn. . . . Even in [an] optimistic scenario, in which the price of the biosimilar is 60 percent less than the price of the brand after rebates and discounts, if the payer is only able to convert 50 percent of its patient users to the biosimilar [because existing patients will tend to stay on the original branded product], the rebate trap ensures that payer total costs actually increase relative to costs prior to biosimilar availability. * * * To avoid the rebate trap, any strategy to reduce spending on biologics through adoption of biosimilars requires a near- complete switch of patient users from the branded biologic to the biosimilar. However, for many chronic diseases, the proportion of patients new to a given biological therapy is less than 20 percent of the total patients taking that drug in a given year. The remainder represents a stable base of patients whose disease is well-maintained while they are using current therapy and thus are unlikely to switch [to the biosimilar].\21\ --------------------------------------------------------------------------- \21\ Aaron Hakim and Joseph S. Ross, ``Obstacles to the Adoption of Biosimilars for Chronic Diseases,'' Journal of the American Medical Association (May 1, 2017), available at http://jamanetwork.com/ journals/jama/article-abstract/2625049 (emphasis added). 67. J&J has further insulated its contracts with insurers from competition by bundling rebates for Remicade with rebates on other products in return for commitments not to cover Inflectra. J&J made it no secret that it would leverage other products as part of its ``Biosimilar Readiness Plan.'' As J&J's Worldwide Chair for Pharmaceuticals made clear on a recent earnings call, ``We are fully prepared to execute our focused biosimilar readiness plan,'' including ``developing innovative contracts . . . [to] utilize the full breadth of our portfolio.'' \22\ The ``full breadth of [J&J's] portfolio'' includes several drugs for which Pfizer does not offer any directly competing alternative. These include drugs such as Simponi (used for rheumatoid arthritis, psoriatic arthritis, ankylosingspondylitis, and ulcerative colitis), Simponi Aria (used for rheumatoid arthritis), and Stelara (used for plaque psoriasis, psoriatic arthritis, and Crohn's disease). These products are widely used, with Simponi/Simponi Aria generating for J&J approximately $1.7 billion in 2016 and Stelara generating for J&J approximately $3.2 billion in 2016. J&J has threatened insurers with the loss of rebates on these other drugs, as well as Remicade, if they do not agree to exclude Inflectra from coverage. --------------------------------------------------------------------------- \22\ Johnson & Johnson, Q3 2016 Results Earnings Call Transcript (Oct. 14, 2016), available at https://seekingalpha.com/search/ transcripts?term=johnson+%26+Johnson+biosimilar. 68. J&J's multi-product bundling, along with its bundling of contestable demand (i.e., new patients) and incontestable demand (i.e., existing Remicade patients), have amplified the anticompetitive effects of J&J's exclusive contracts, and made the exclusivity provided by those contracts even more durable. Insurers have made it clear to Pfizer that its net cost for Inflectra would need to be low enough to offset the loss of J&J rebates. But, because of the combined effect of these bundles, Pfizer cannot offset the financial penalties that J&J threatens to impose on insurers who do not agree to exclusivity. As a result, Pfizer is economically prohibited from competing for coverage by the major insurers--even when their exclusive contracts with J&J expire. J&J can use the same bundling strategies to ensure continuation --------------------------------------------------------------------------- of the exclusionary pattern. B. J&J's Improper Insurer-Level Contracts Deter Hospitals and Clinics from Purchasing Inflectra, Thus Amplifying Foreclosure 69. Providers are unwilling to stock a drug product where there is significant uncertainty about whether it will be reimbursed by health insurers; because they administer infliximab onsite, providers must expend funds for the product in the first instance, then seek reimbursement after providing treatment. The provider has theoretical recourse against the patient where coverage is denied, but the prospect of securing payment in full from the patient is bleak, especially for drugs as costly as Remicade. As a result, where a significant portion of a provider's patients are insured by plans that have agreed to exclude Inflectra--pursuant to the types of contracts described above-- the provider is unlikely to offer Inflectra for any of its patients, to avoid being caught with no reimbursement. 70. As a recent article in Bloomberg stated: Ascension Health, a nearly 23,000-bed nonprofit hospital system based in St. Louis, spends $55 million a year on Remicade, more than any other drug. Using Inflectra, part of a new class of medicines called biosimilars, would save it at least $10 million annually, according to Ascension's chief pharmacist, Roy Guharoy. He met with Pfizer and planned to integrate Inflectra into care more often until learning that insurers preferred to stay with Remicade. ``This we did not expect,'' Guharoy said. ``If the insurance companies force us to use the branded product, of course our hands are tied.'' \23\ --------------------------------------------------------------------------- \23\ Jared S. Hopkins, What's Harder Than Making Copycat Biotech Drugs? Selling Them, Bloomberg (Aug. 15, 2017). In short, provider purchases are driven by the coverage stated by --------------------------------------------------------------------------- commercial insurers. 71. Having created reimbursement concerns through its exclusionary contracts with health insurers, J&J touts the excluded status of Inflectra in its marketing communications, knowing that doing so will discourage providers from stocking the new biosimilar. As this brochure shows, J&J markets the ``fail first'' requirement as a selling point despite the fact that such a provision is medically inappropriate and despite FDA's determination that there are no clinically meaningful differences between the two products. Thus the brochure touts that Remicade is ``Preferred Over Inflectra . . . Inflectra requires trial and failure on Remicade prior to [Inflectra] utilization.'' [GRAPHIC(S) NOT AVAILABLE IN TIFF FORMAT] 72. Given the widespread gaps in Inflectra's insurance coverage-- caused by J&J--providers using infliximab have overwhelmingly chosen to stock only Remicade (which is essentially universally covered given its long tenure and dominant position) rather than deal with the risk of possible denials of coverage for Inflectra. Thus, providers have declined to purchase Inflectra across the board, even for patients covered by commercial or government insurance plans that do cover the product. The effective foreclosure of biosimilars thereby is expanded well beyond the 70 percent of commercially insured patients directly foreclosed by J&J's insurer contracts. Indeed, as of September 1, 2017, about 90 percent of healthcare provider accounts using infliximab had purchased no Inflectra at all. C. J&J Has Further Barred Access Through Exclusionary Contracts with Providers 73. To further amplify Inflectra's foreclosure--even beyond the population of patients covered by insurance plans that have agreed to J&J's exclusivity terms, and the spillover effect on providers discussed above--J&J has imposed exclusionary contracts on providers themselves (e.g., clinics, hospitals, etc.). 74. After Inflectra's introduction, J&J began offering certain large providers additional rebates and/or discounts on Remicade, but only if the provider committed to buy Remicade for nearly all of its infliximab needs. To be eligible for rebates, J&J required providers to maintain purchase levels for Remicade at very close to the levels of the year before Inflectra's launch--when Remicade was the only infliximab option. With about 30 percent of prescriptions in any year representing new patients (and a certain percentage of existing patients exiting therapy each year), this condition also requires providers to use Remicade for new patients if they wish to secure payment from J&J, thus bundling contestable and incontestable demand for Remicade. Like its insurer-level contracts, these contracts as a practical matter make Remicade the exclusive infliximab with the participating providers. 75. J&J has also used multi-product bundling in its provider-level contracts. As one analyst reported, ``J&J bundled several drugs and medical devices for larger hospitals, making Inflectra less economical.'' \24\ Conditioning rebates linked to other J&J products upon a promise not to do business with Inflectra only exacerbates the exclusionary nature of J&J's contracts. --------------------------------------------------------------------------- \24\ Gal, supra note 15, at 1. 76. Pfizer was and is prepared to negotiate with providers to make Inflectra the lower-priced infliximab option on a per-unit basis, and has even offered to guarantee that Inflectra would be less expensive unit-for-unit than Remicade. But as with insurer contracts, to secure the right to deal freely as to Inflectra (i.e., principally as to new patients), the providers would lose significant J&J rebates on their --------------------------------------------------------------------------- existing Remicade patient bases. 77. For Pfizer to make up the J&J rebates/discounts that insurers and providers would lose on their existing Remicade patients, Pfizer would have to price Inflectra below its own average variable cost. This is because the lost J&J rebates/discounts are based on the much larger base of existing Remicade patients, whereas Pfizer would be serving a much smaller group of new patients, at least in the near term. 78. When the total amount of discounts and rebates that J&J offers to insurers and providers under the contracts described herein, including multi-product bundle contracts, is attributed to the portion of Remicade sales that is contestable by a biosimilar like Inflectra, J&J is pricing Remicade below its own average variable cost. As a result, biosimilar competition to Remicade is foreclosed. 79. The combined effect of J&J's multifaceted exclusionary scheme has been to foreclose Inflectra from approximately 90 percent of the provider account distribution channel essential to connecting Inflectra with patients of any kind. J&J HAS MONOPOLY POWER IN THE RELEVANT MARKETS 80. Monopoly power is the ability of a single seller to raise prices above the competitive price level without losing significant business. 81. For years before Inflectra's entry, J&J's ASP for Remicade increased, yet Remicade did not lose business. Between 2007 and 2017, Remicade's ASP increased more than 62 percent. Despite Remicade's price hikes, unit sales of Remicade have actually grown 15 percent during the period from 2012 to 2016. 82. Inflectra's introduction has done nothing to erode Remicade's monopoly power: Since Inflectra was launched, Remicade's ASP has continued to increase without impacting Remicade's market position. Ten months after Inflectra was introduced, Remicade still accounts for over 96 percent of all infliximab sales. Indeed, J&J has confirmed that ``biosimilar competition'' has had ``very little impact'' on Remicade.\25\ --------------------------------------------------------------------------- \25\ Johnson & Johnson, Q1 2017 Results Earnings Call Transcript (Apr. 18, 2017), available at https://seekingalpha.com/search/ transcripts?term=johnson+%26+Johnson+biosimilar. 83. As noted, infliximab is an infusion-administered TNF-inhibiting immunosuppressant with FDA approved indications for rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, ulcerative colitis, Crohn's disease, and plaque psoriasis (together, the --------------------------------------------------------------------------- ``Relevant Indications''). 84. The broadest appropriate relevant product market is infusion- administered drugs whose approved labeling from the FDA (a) encompasses one or more of the Relevant Indications, and (b) is without restriction for the applicable Relevant Indication, that is to say, the labeling does not specify that the drug may be used for the applicable Relevant Indication only after the patient has not responded to another therapy (the ``Relevant Product Market'').\26\ Remicade enjoys a share of over 60 percent in the Relevant Product Market, nearly the same share it had before Inflectra entered. --------------------------------------------------------------------------- \26\ For example, the FDA approved Rituxan for the treatment of moderate to severe active rheumatoid arthritis in adults only after treatment with at least one other TNF antagonist has been used and did not work well enough. 85. The following infusion-administered therapies have been --------------------------------------------------------------------------- approved as unrestricted therapies for the Relevant Indications: Rheumatoid Arthritis: Remicade (infliximab) (J&J) (TNF- inhibitingimmuno-suppressant) Simponi Aria (golimumab) (J&J) (TNF- inhibiting immuno-suppressant) Inflectra (infliximab) (Pfizer) (TNF- inhibitingimmuno-suppressant) Renflexis (infliximab) (Merck) (TNF- inhibitingimmuno-suppressant) Orencia IV (abatacept) (Bristol-Myers Squibb) (synthetic recombinant DNA technology immune-suppressant) Actemra IV (tocilizumab) (Roche) (interleukin-6 blocker) (IL-6 blocker) Psoriatic Arthritis: Remicade (infliximab) (J&J) (TNF- inhibitingimmuno-suppressant) Stelara IV (ustekinumab) (J&J) (human interleukin-12 and -23 antagonist) Inflectra (infliximab) (Pfizer) (TNF- inhibitingimmuno-suppressant) Renflexis (infliximab) (Merck) (TNF- inhibitingimmuno-suppressant) Orencia IV (abatacept) (Bristol-Myers Squibb) (synthetic recombinant DNA technology immuno-suppressant) Ankylosing Spondylitis: Remicade (infliximab) (J&J) (TNF- inhibitingimmuno-suppressant) Inflectra (infliximab) (Pfizer) (TNF- inhibitingimmuno-suppressant) Renflexis (infliximab) (Merck) (TNF- inhibitingimmuno-suppressant) Plaque Psoriasis: Remicade (infliximab) (J&J) (TNF- inhibitingimmuno-suppressant) Stelara IV (ustekinumab)(J&J) (human interleukin-12 and -23 antagonist) Inflectra (infliximab) (Pfizer) (TNF- inhibitingimmuno-suppressant) Renflexis (infliximab) (Merck) (TNF- inhibitingimmuno-suppressant) Crohn's Disease: Remicade (infliximab) (J&J) (TNF- inhibitingimmuno-suppressant) Stelara IV (ustekinumab) (J&J) (human interleukin-12 and -23 antagonist) Inflectra (infliximab) (Pfizer) (TNF- inhibitingimmuno-suppressant) Renflexis (infliximab) (Merck) (TNF- inhibitingimmuno-suppressant) Entyvio (vedolizumab) (Takeda) (integrin receptor antagonist monoclonal antibody) Ulcerative Colitis: Remicade (infliximab) (J&J) (TNF- inhibitingimmuno-suppressant) Inflectra (infliximab) (Pfizer) (TNF- inhibitingimmuno-suppressant) Renflexis (infliximab) (Merck) (TNF- inhibitingimmuno-suppressant) Entyvio (vedolizumab) (Takeda) (integrin receptor antagonist monoclonal antibody) These infusion therapies are referred to collectively as the ``Relevant Products.'' 86. Certain non-infusion drugs are also indicated to treat the Relevant Indications. None of those drugs, however, is a reasonable substitute for the infusion- administered products. None significantly constrains the prices J&J is able to charge for Remicade. 87. The non-infusion products approved for the Relevant Indications include oral medications (e.g., Xeljanz) and self-injectables (e.g., Humira, Enbrel). These products are patient-administered. Infusion drugs, by contrast, must be delivered by healthcare professionals in a clinical setting (e.g., hospitals or infusion centers) during infusion sessions that take upwards of two hours. 88. Physicians are not likely to switch from prescribing their patients infliximab to prescribing those non-infusion products in response to a small but significant non-transitory change in the price of infliximab. 89. Not only are the infusion and non-infusion treatments different kinds of therapies, but they are most often sold to different buyers, on different contracts, and are distributed by different means: Infliximab is, as described above, sold primarily to hospitals and clinics and is almost never stocked by retail pharmacies (only rarely being stocked by certain specialty pharmacies). After administering the infusion treatments to their patients, the hospitals and clinics seek reimbursement from the patients' insurers or government payers. By contrast, non-infusion drugs such as Xeljanz, Humira, and Enbrel are primarily sold to and distributed in the pharmacy channels. Physicians who prescribe these non-infusion drugs generally do not administer the treatments and do not bear financial risk with respect to the drug selected. Non-infusion drugs are also typically covered by insurance through a pharmacy benefit plan. These are products that insured patients obtain using their ``pharmacy'' cards. Such drugs are put out for bid periodically by insurers and/or pharmacybenefit managers. The bidding process generally does not even include infusion and other therapies not stocked in a retail pharmacy. By contrast, infusion therapies generally are treated as part of the basic medical coverage provided by health insurers. Infusion therapies are thus generally put out for bid separately from self-administered therapies. 90. Beyond the medical reasons physicians may have for prescribing an infusion therapy as opposed to a non-infusion therapy, patients exhibit strong preferences for one form of therapy over another. Patients with active lifestyles often prefer self-administered treatments. Infusion therapy, on the other hand, is often preferred by patients with needle aversions, or by patients who prefer to have their treatments administered by medical professionals. 91. In addition, infusion and non-infusion therapies are offered at very different price points: On an annual basis, Enbrel and Humira (which are self-administered therapies) at list price are at least twice as expensive as Remicade (which is an infusion therapy) for patients stabilized on them. 92. Because of these various factors, a small but significant non- transitory increase in price of infusion therapies would not have a meaningful impact on the demand for non-infusion therapies, and vice- versa. 93. As noted, the Relevant Product Market includes certain segments that qualify themselves as Relevant Markets, in which J&J also possesses monopolypower. For example: 94. Specific-use product markets. Specific-use product markets are predicated on infusion-administered therapies for the Relevant Indications. A small but significant nontransitory increase in price for an infusion product in each of these specific-use product markets would not cause substitution to non-infusion medicines approved for the same indication. In each category, Remicade has been the dominant infusion-administered therapy. The categories are as follows: Infusion-administered therapies for Crohn's disease. Remicade accounts for over 70 percent of prescriptions to patients of infusion-based drugs indicated for Crohn's disease. Infusion-administered therapies for rheumatoid arthritis. Remicade accounts for nearly 55 percent of prescriptions to patients of infusion-based drugs indicated for rheumatoid arthritis. When combined with the share of its product Simponi Aria, J&J commands an aggregate of nearly 65 percent of prescriptions to patients in this category. Infusion-administered therapies for ulcerative colitis. Remicade accounts for nearly 70 percent of prescriptions to patients of infusion-based drugs indicated for ulcerative colitis. Infusion-administered therapies for psoriatic arthritis. Remicade accounts for over 95 percent of prescriptions to patients of infusion-based drugs indicated for psoriatic arthritis. Infusion-administered therapies for ankylosing spondylitis. Remicade accounts for over 95 percent of prescriptions to patients of infusion-based drugs indicated for ankylosing spondylitis. Infusion-administered therapies for plaque psoriasis. Remicade accounts for over 95 percent of prescriptions to patients of infusion-based drugs for plaque psoriasis. 95. Clinic-based product market. The Relevant Product Market encompasses a submarket consisting of sales of the Relevant Products to non-hospital clinics (including freestanding clinics and physician offices with infusion chairs) that administer infusion therapies to patients. Such a submarket is properly treated as a relevant submarket among other reasons because J&J is able to price discriminate between hospitals and non-hospital clinics. The U.S. antitrust enforcement agencies and economists recognize that relevant antitrust product markets can be based on categories of customers against whom sellers can exercise price discrimination, i.e., differential pricing.\27\ Non- hospital clinics are subject to successful price discrimination by J&J. J&J can and does identify and target clinics for differential pricing. There are significant differences in the rebates and discounts J&J makes available to non-hospital clinics as compared to hospital customers. Moreover, a small but significant non-transitory increase in the price of Remicade or other Relevant Products will not induce infusion clinics to switch to self-administered therapies. A very substantial percentage of provider accounts that purchase infliximab are non-hospital clinics. --------------------------------------------------------------------------- \27\ See, e.g., U.S. Department of Justice and Federal Trade Commission Horizontal Merger Guidelines (2010), Sec. 3. 96. Product markets for new and existing patients. As described above, J&J has a substantial base of existing Remicade patients, the substantial majority of whom are not likely to switch to another therapy, even a biosimilar, if they have achieved relief with Remicade--even in response to a small but significant non- transitory increase in price for Remicade. By contrast, for new patients who are candidates for infusion-administered therapies for the Relevant Indications, Inflectra is a reasonable substitute for Remicade. Thus, there is a distinct product market for sales of Relevant Products to new patients in need of infusion-administered therapies for the Relevant Indications. There is also a distinct product market for patients already stabilized on Remicade--a market dominated by Remicade. As described above, J&J's scheme has bundled its control over the latter market (for patients stabilized on Remicade) to thwart competition in the former market (for new patients in need of --------------------------------------------------------------------------- infusion therapy). 97. Infliximab product market. After discovery, the data may also support an infliximab-only product market. Among other things, J&J has been able to raise prices for Remicade consistently without losing significant sales to other branded drug products. Both J&J and Pfizer consider Remicade and Inflectra to be particularly close substitutes. For example, J&J's marketing materials focus on comparisons of price and clinical effectiveness between Remicade and infliximab biosimilars, and do not reference any other therapies, and its ``Biosimilar Readiness Plan'' similarly ignores other therapies, focusing instead on the unique competitive threat posed by biosimilars. Inflectra's marketing materials likewise focus on Remicade, not on other therapies. 98. Barriers to entry. Substantial barriers to entry exist to developing other infusion-administered drug therapies for the Relevant Indications generally, and infusion-administered TNF inhibitors specifically. The development of a new therapy requires tens if not hundreds of millions of dollars and substantial risk, as any new product must survive years of research and development, clinical trials, and FDA approval. If left unchecked, J&J's conduct will serve as an additional barrier to entry, as potential new entrants will recognize that they will be unable to break J&J's ``rebate trap'' and thus to profitably enter the Relevant Markets--and consequently will not invest the resources necessary to develop biosimilars. 99. While a second biosimilar to Remicade has been approved--called Renflexis, sponsored by Merck and Samsung--the sponsoring firms had to overcome just the kind of substantial burdens noted above, and began the effort long before J&J commenced its scheme to exclude biosimilar competition. J&J itself has expressed confidence in maintaining its Remicade dominance despite the potential entry of Renflexisbased on its exclusionary contracting strategy. Pfizer has received marketplace feedback that Renflexis will face the same access challenges from J&J's scheme as Inflectra. 100. J&J's scheme--including coercive contracts bundling the incontestable demand (existing patients) with contestable demand (new patients), and promoting the results of its exclusionary insurer-level contracts to create uncertainty about Inflectra among providers--has led directly, with J&J's active encouragement, to nearly all provider accounts that use infliximab declining to purchase Inflectra at all. Even if some portion of a provider's patient base may be covered, providers are unwilling to risk using Inflectra only to ultimately be denied coverage. A single denied claim can cost a provider in excess of $4,000, whereas the typical provider savings in product acquisition cost for a covered Inflectra claim is $200-300. Because Remicade is nearly universally covered, providers have taken the ``safe'' option and stocked Remicade over Inflectra, thus increasing the already- substantial foreclosure caused by J&J's exclusionary contracts. Thus, as a practical matter, J&J's scheme has foreclosed Inflectra from approximately 90 percent of provider accounts using infliximab, the essential channel of distribution for infliximab. And, as noted, in terms of sales, Remicade continues to control over 96 percent of infliximab unit sales. 101. Geographic market. The relevant geographic market for the Relevant Markets alleged herein is the United States of America and its possessions and territories, as these products are marketed and sold on a national basis. J&J's CONDUCT HAS STIFLED COMPETITION IN THE RELEVANT MARKETS, THEREBY MAINTAINING AND ENHANCING ITS MONOPOLY POWER AND INJURING PFIZER 102. J&J's scheme has led to the near total foreclosure of Inflectra with patients across the country. First, its exclusionary contracts with health insurers alone--including with most of the largest health insurers in the country--have foreclosed Pfizer's ability to compete for at least 70 percent of patients covered by commercial health insurance plans in the United States. Second, J&J's exclusionary contracts with certain providers have foreclosed Pfizer's ability to compete even for patients covered by plans that do provide reimbursement for Inflectra. And, as discussed, the reimbursement challenges (created by J&J) have led most provider accounts to decline to purchase Inflectra at all, with approximately 90 percent of provider accounts that use infliximab across the country not stocking Inflectra at all. As of September 2017, J&J maintained over 96 percent share of infliximab unit sales in the U.S. 103. Despite vigorous efforts to compete--including offering guarantees that Inflectra would be less expensive unit-for-unit than Remicade--Pfizer has been foreclosed from gaining a competitive foothold as a direct result of J&J's scheme. In the absence of Remicade's exclusionary practices, Inflectra's growth in the Relevant Markets would be substantially greater than it has been, and would be substantially larger in the future. J&J's conduct has deprived Pfizer of (a) past profits; (b) future profits; and (c) the value of invested capital from unrealized efforts to enter and expand in the Relevant Markets. Further, Pfizer's current and prospective customer relationships and goodwill have been, and will continue to be, impaired. J&J's conduct, if allowed to continue, will also dampen the incentives of Pfizer and other biosimilar developers to invest the substantial resources needed to bring biosimilars to the market. Thus, the aims of the BPCIA will have been thwarted. 104. J&J's activities have not only harmed Pfizer, they have caused substantial harm to the competitive process as well as to government payers and to consumers, who have been deprived of the principal benefits of competition--more choices and lower prices. The anticompetitive effects of J&J's conduct are evident in its pricing of Remicade since Inflectra's entry. Despite the fact that Pfizer has offered substantial discounts and a lower ASP to compete for business with insurers and healthcare providers, J&J has been able to increase the price of Remicade without losing any significant share or volume of sales to Pfizer (or any other competitor). J&J's prices for Remicade have been increasing by every measure. J&J has increased Remicade list prices twice since FDA approval of Inflectra. These increases alone raised Remicade's list price nearly 9 percent. Remicade's actual ASP (which, as noted above, is net of discounts, rebates, and other price concessions) has also increased since Inflectra's entry-- negating any claim that J&J's rebates qualify as meaningful price competition. 105. There is no efficiency or cost-reducing justification for J&J's coercive and exclusionary insurer- or provider-level contract terms. J&J has not achieved improved production costs, or economies of scale or scope through its contracting strategies. J&J also has achieved no improvements in the Remicade treatment through its contracting strategies. 106. If J&J's conduct is not prohibited, it will be adopted by other originator biologics firms aiming to preserve their dominant positions. As the first major biosimilar approval, this case will be a bellwether for the success of Congress's biosimilars initiative, as embodied in the BPCIA. CLAIMS FOR RELIEF FIRST CLAIM FOR RELIEF Violation of 15 U.S.C. Sec. 2 Monopolization of All Relevant Markets 107. Pfizer repeats and realleges Paragraphs 1 through 106 as set forth herein. 108. J&J has monopolized the Relevant Markets in violation of Section 2 of the Sherman Act. 109. J&J has monopoly power in the Relevant Markets. 110. Through the scheme described above, and other conduct likely to be revealed in discovery, J&J has willfully and unlawfully maintained and enhanced its monopoly power in violation of Section 2 of the Sherman Act. J&J's scheme constitutes exclusionary conduct within the meaning of Section 2 of the Sherman Act. 111. J&J's scheme has stifled competition in the Relevant Markets and thwarted Congress's purpose in enacting the BPCIA. 112. Among other things, given that (a) J&J imposed explicit conditions that insurers and providers eliminate (or almost completely curtail) their dealings with infliximab biosimilars, and (b) J&J's ASP for Remicade has actually increased since the biosimilar entered, J&J's pricing is not the clearly predominant means by which competition has been foreclosed in the Relevant Markets. 113. Even if price were deemed to be the clearly predominant means by which competition has been foreclosed, when the total amount of discounts and rebates that J&J offers to insurers and providers under the contracts described herein, including multi-product bundle contracts, is attributed to the portion of Remicade sales that is contestable by a biosimilar like Inflectra, J&J is pricing Remicade below its own average variable cost. 114. As a result of J&J's conduct, and the harm to competition caused by that conduct, Pfizer has suffered substantial and continuing injuries. SECOND CLAIM FOR RELIEF Violation of 15 U.S.C. Sec. 2 Attempted Monopolization of All Relevant Markets 115. Pfizer repeats and realleges Paragraphs 1 through 114 as set forth herein. 116. J&J has attempted to monopolize the Relevant Markets in violation of Section 2 of the Sherman Act. 117. J&J is violating Section 2 of the Sherman Act by attempting to implement the anticompetitive scheme set forth above with the specific intent to monopolize the Relevant Markets. J&J's scheme constitutes exclusionary conduct within the meaning of Section 2 of the Sherman Act. 118. There is a dangerous probability that J&J will succeed in monopolizing the Relevant Markets through its anticompetitive scheme. 119. J&J's scheme has stifled competition in the Relevant Markets and thwarted Congress's purpose in enacting the BPCIA. 120. Among other things, given that (a) J&J imposed explicit conditions that insurers and providers eliminate (or almost completely curtail) their dealings with infliximab biosimilars, and (b) J&J's ASP for Remicade has actually increased since the biosimilar entered, J&J's pricing is not the clearly predominant means by which competition is dangerously likely to be foreclosed in the Relevant Markets. 121. Even if price were deemed to be the clearly predominant means by which competition is dangerously likely to be foreclosed, when the total amount of discounts and rebates that J&J offers to insurers and providers under the contracts described herein, including multi-product bundle contracts, is attributed to the portion of Remicade sales that is contestable by a biosimilar like Inflectra, J&J is pricing Remicade below its own average variable cost. 122. As a result of J&J's conduct, and the harm to competition caused by that conduct, Pfizer has suffered substantial and continuing injuries. THIRD CLAIM FOR RELIEF Violation of 15 U.S.C. Sec. 14 Sale on Condition to Exclude Inflectra and Other Infliximab Biosimilars or Impose a Fail First Requirement and to Force Use of Remicade in All Relevant Markets 123. Pfizer repeats and realleges Paragraphs 1 through 122 as set forth herein. 124. J&J has entered into agreements with insurers (which reimburse Remicade) and providers (which purchase Remicade), whereby it has conditioned the availability of discounts, rebates, and/or other price concessions on insurers and/or providers eliminating or drastically curtailing their dealings with Inflectra (or any other infliximab biosimilar). 125. J&J's agreements function as exclusive agreements, what are for all practical purposes sole-source agreements, the effect of which is to foreclose substantially competition from rivals, such as Pfizer, in the sale of the infliximab to medical providers, in violation of Section 3 of the Clayton Act. 126. The essence of the J&J-insurer contracts is to pay the insurers to exclude biosimilar alternatives from their prescription drug or medical benefits coverage, whereby the insurers either deny coverage altogether or restrict coverage to only the rarest of circumstances. The insurers, as the payers for the treatment, have the ability to exclude selected drugs from coverage and as a result, patients and providers do not have a practical ability to choose Inflectra or other infliximab biosimilars over Remicade where coverage is not available. Moreover, because insurers wield power over providers with the ability to grant or withhold coverage for treatment, and because providers are risk-averse when it comes to buying and stocking medications such as infliximab, the providers are effectively compelled to stock Remicade exclusively. 127. The intent and effect of the insurers' performance of these contracts is to cause providers to forgo alternatives and to drive all treatment sales to J&J. The result of the J&J insurer contracts thus is the amplification of foreclosure, such that Inflectra and other biosimilars are denied access to approximately 90 percent of provider accounts and foreclosed from competition in the Relevant Markets. 128. Because providers and insurers are the gateway for the distribution and sale of the Relevant Products, there are no viable alternative means of distribution or sale and substantial foreclosure exists. Biosimilar competitors to J&J have no practical alternative means of selling infliximab to patients. 129. These de facto exclusive arrangements are in effect durable long-term agreements because the incentives J&J has exploited are not likely to change. So long as J&J's contracts remain in place, biosimilars will not be able to dent J&J's base of existing patients, and the incentives underlying J&J's contracts will remain. No insurer can practically walk away from and not continue to perform under the J&J agreement due to the above-discussed penalties. 130. The effect of each such agreement is and has been to substantially lessen competition in the Relevant Markets. The aggregate impact of such agreements is and has been to substantially lessen competition or tend to create a monopoly in the Relevant Markets. 131. By imposing such conditional contracts, J&J is directly and proximately foreclosing Pfizer and other competitors from a substantial portion of the Relevant Markets. 132. J&J's conduct has had anticompetitive effects in the Relevant Markets, including, without limitation, the effects described above in Paragraphs 102 through 106. 133. As a result of J&J's conduct, and the harm to competition caused by that conduct, Pfizer has suffered substantial and continuing injuries. FOURTH CLAIM FOR RELIEF Violation of 15 U.S.C. Sec. 1 Agreements in Restraint of Trade in All Relevant Markets 134. Pfizer repeats and realleges Paragraphs 1 through 133 as set forth herein. 135. J&J has entered into agreements with insurers and providers of Remicade with the purpose and effect of unreasonably restraining trade and commerce in the Relevant Markets. 136. J&J's solicitation and enforcement of the exclusionary contracts described above constitute unlawful agreements, contracts, and concerted activity that unreasonably restrain trade in the Relevant Markets in violation of Section 1 of the Sherman Act. 137. J&J's conduct has had anticompetitive effects in the Relevant Markets, including, without limitation, the effects described above in Paragraphs 102 through 106. 138. Among other things, given that (a) J&J imposed explicit conditions that insurers and providers eliminate (or almost completely curtail) their dealings with infliximab biosimilars, and (b) J&J's ASP for Remicade has actually increased since the biosimilar entered, J&J's pricing is not the clearly predominant means by which competition has been foreclosed in the Relevant Markets. 139. Even if price were deemed to be the clearly predominant means by which competition has been foreclosed, when the total amount of discounts and rebates that J&J offers to insurers and providers under the contracts described herein, including multi-product bundle contracts, is attributed to the portion of Remicade sales that is contestable by a biosimilar like Inflectra, J&J is pricing Remicade below its own average variable cost. 140. As a result of J&J's conduct, and the harm to competition caused by that conduct, Pfizer has suffered substantial and continuing injuries. PRAYER FOR RELIEF 141. WHEREFORE, Pfizer respectfully prays that the Court enter judgment against J&J and in favor of Pfizer, as follows: a. Awarding Pfizer money damages, trebled pursuant to law, in an amount in excess of $150,000.00 (exclusive of interest and costs); b. Awarding Pfizer the costs of the lawsuit, including its reasonable attorneys' fees and court costs; c. Declaring J&J's conduct unlawful and in violation of the above- referenced statutes; d. Entering appropriate preliminary and permanent injunctive relief barring J&J from continuing to undertake its anticompetitive scheme, including its exclusionary contracts; and e. Ordering such other and further relief as the Court may deem just, proper, and equitable. JURY TRIAL DEMANDED 142. Pfizer demands a trial by jury for all issues triable by jury. Dated: September 20, 2017 . Respectfully submitted, Philadelphia, PA Robert Fiebach, Esq. (PA 02812) Peter M. Ryan, Esq. (PA 81816) Cozen O' Connor One Liberty Place 1650 Market Street, Suite 2800 Philadelphia, PA 19103 Tel: +1 215 665 4166 Fax: +1 215 665 2013 [email protected] [email protected] Robert A. Milne, Esq. (Pro Hac Vice forthcoming) Michael J. Gallagher, Esq. (Pro Hac Vice forthcoming) Bryan D. Gant, Esq. (Pro Hac Vice forthcoming) White & Case LLP 1221 Avenue of the Americas New York, NY 10025-1095 Tel: (212) 819-8200 Fax: (212) 354-8113 [email protected] [email protected] [email protected] Elliott E. Dionisio, Esq. (Pro Hac Vice forthcoming) White & Case LLP 555 S. Flower Street, Suite 2700 Los Angeles, CA 90071 2433 Tel: (213) 620-7700 Fax: (213) 452-2329 [email protected] Counsel for Pfizer Inc. ______ Prepared Statement of Olivier Brandicourt, M.D., Chief Executive Officer, Sanofi Chairman Grassley, Ranking Member Wyden, and members of the committee, thank you for the opportunity to appear before the Senate Committee on Finance to discuss pharmaceutical pricing, affordability, and patient access in the United States. I am Dr. Olivier Brandicourt, the chief executive officer of Sanofi. At Sanofi, we work passionately every day to understand and address the health care needs of patients around the world. We are dedicated to solving patients' most serious health challenges in numerous therapeutic areas, including diabetes, cardiovascular disease, immunology, oncology, multiple sclerosis (MS), rare diseases, and rare blood disorders. We are also devoted to preventing diseases through the research, development, and delivery of vaccines. And we contribute to improving the health of people around the world through our broad portfolio of consumer health products. Sanofi's U.S. subsidiaries have a rich history in the United States dating back over 100 years. We currently employ more than 13,000 professionals across the United States in a broad range of critical roles, including business operations, research and development, and manufacturing, with our most significant presence in Massachusetts, where we are the largest employer in the life sciences industry, and major centers of operation in New Jersey, Pennsylvania, and Tennessee. Last year, Sanofi spent almost $7 billion on research and development, an increase of approximately 7 percent from 2017, which reflects our commitment to bringing better therapies to patients. Sanofi plans to maintain this level of R&D investment through 2021, and our R&D pipeline now contains 81 projects, including 33 new molecular entities in clinical development, and 35 projects that are in Phase III or have been submitted to regulatory authorities. This investment means that Sanofi potentially will seek approval for nine new medications in the next three years, primarily in therapeutic areas where Sanofi sees the greatest nexus between our expertise and patient need: diabetes, vaccines, oncology, immunology, rare diseases, and rare blood disorders. Our work in R&D includes more than a dozen compounds for the treatment of various kinds of cancers, and we are employing cutting- edge approaches in an effort to make significant advances for patients. Our research includes potential treatments to help the body's own immune system fight cancer, and antibody drug conjugates that we believe can deliver cytotoxic drugs to tumors while sparing normal tissue. Earlier this month, we announced successful results with one such candidate in a mid-stage trial in lung cancer, and we intend to initiate a pivotal study later this year. i. rising costs for patients While the research and development landscape has fundamentally changed, the landscape in which patients access medications has also fundamentally changed, and not for the better. Affordability of medicines is a real and growing challenge for too many Americans. We understand the anger of patients who cannot afford the medicines they or their loved ones need due to rising out-of-pocket drug costs. There is no single root cause to the problem of rising patient out- of-pocket costs, and in order to develop meaningful solutions for patients, it is critical to take a comprehensive look at what is driving rising costs for patients. Given the number of factors that contribute to determining out-of-pocket costs for patients, every part of the supply chain, including manufacturers, has a role to play in solving this problem. We want everyone--including patients, providers, payers, pharmacy benefit managers (PBMs), policy makers, and regulators--to understand why we set prices as we do, and to reaffirm our commitment to our core principles of access, affordability and innovation. An important component of pricing includes the intersection between the list prices of our medicines, the net prices we actually receive after accounting for all rebates and other discounts, and out-of-pocket costs. While list prices often receive the most attention, they reflect the initial price we set for our medicines. They are not the amount Sanofi receives nor the prices typically paid by government and commercial insurers, employers, or PBMs. Under the current system, players within the supply chain--including PBMs, plans, wholesalers, distributors, and group purchasing organizations--receive either rebates and/or fees based on a percentage of the list price. Their economic incentives are therefore directly linked to the list price. And as long as the net price grows at a predictable rate, the greater the list price, the greater the economic returns for many players in the supply chain. Manufacturers, in turn, must account for anticipated rebates and other discounts when setting their list price. Thus, list price is the starting point for negotiations with payers, and it is often the basis for patient out-of-pocket costs. But focusing solely on the list price does not tell the whole story. In the current system, manufacturers pay significant rebates as a percentage of the list price to both government and private payers, as well as other intermediaries, in an effort to improve access for patients. In 2018, 55 percent of Sanofi's gross sales were given back to payers as rebates, including $4.5 billion in mandatory rebates to government payers and $7.3 billion in discretionary rebates. As described later in my testimony, due to these rebates, the average aggregate net price of our products, including our insulin products, actually has declined over the last number of years. Sanofi provides rebates to PBMs and health plans to improve patient access to, and affordability for, Sanofi medicines. We want these rebates, which lower net prices, to benefit patients. Unfortunately, under the current system, savings from rebates are not consistently passed through to patients in the form of lower deductibles, co- payments or coinsurance amounts. For some patients, out-of-pocket costs are calculated based on a medicine's list price. However, based on variability in plan design, the list price alone does not explain patients' increasing affordability issues. Sanofi and Sanofi Genzyme U.S. Gross to Net 2018 Breakdown * [GRAPHIC(S) NOT AVAILABLE IN TIFF FORMAT] ------------------------------------------------------------------------ ------------------------------------------------------------------------- * Below are the summarized categories (by type) for various transactions: Mandatory Rebates: Medicaid, VA-DOD, Tricare, 340B, Medicare Coverage Gap Discretionary Rebates: Commercial, Medicare, Managed Medicaid, Medicaid Supplemental, GPO, Institutional Discounts Government Purchasing Organization (GPO) Fees & Coupons: Fees paid for administration of Sanofi's agreements with Group Purchasing Organizations on behalf of their members and various copay assistance programs DPA Fees: Performance based fees earned by wholesalers for providing complete sales information and maintaining targeting inventory rates Cash Discounts: Trade discounts offered to wholesalers for prompt payment of invoices Sales Returns: Netted with Clawback, Other Corrections/Credit Memos ------------------------------------------------------------------------ For instance, in some cases, affordability issues are the result of changes in health plan designs, such as the increase in the number of high deductible health plans. Among those with private health insurance, enrollment in high deductible health plans (HDHPs) has generally increased since 2010. The design of these plans generally requires patients to pay the full list price of medicines during the deductible phase of the program, rather than the negotiated drug price available when the insurance portion kicks in. [GRAPHIC(S) NOT AVAILABLE IN TIFF FORMAT] In other cases, affordability issues are caused by changes in insurance design which increasingly ask patients to pay higher cost- sharing for their medicines, even when the price of those medicines has stayed relatively flat or has declined for the health plan. For example, as noted later in my testimony, the average net price of Lantus, our most prescribed insulin, has declined by over 30 percent since 2012, while the average out-of-pocket burden for patients with commercial insurance and Medicare has increased by approximately 60 percent over that same period. In this case, not only are discounts apparently not being passed on to patients, but patients are in fact being asked to pay more when PBMs and health plans are paying less for the medicine. This situation defies logic and should not happen. Increasing out-of-pocket costs also can result from changes to prescription drug formularies, which have a significant impact on the amount of out-of-pocket costs a patient will be asked to pay. A recent opinion piece in The New York Times \1\ powerfully highlights how changes to prescription drug formularies not only can create confusion and frustration for providers and patients, but also ultimately increase costs for patients when the medicines they need are not covered on a formulary's preferred tier. --------------------------------------------------------------------------- \1\ See https://www.nytimes.com/2019/01/18/opinion/cost-insurance- diabetes-insulin.html. The impact of the role each of these factors plays in out-of-pocket costs for any individual patient is highly variable, thus compounding the complexity of this issue. Out-of-pocket costs for a medicine for any particular patient depend on a number of factors in addition to list price, including: (1) what portion, if any, of a manufacturer's rebates a PBM or payer passes through to the patient, (2) the benefit design of the patient's health plan, and (3) the level of reimbursement negotiated between the patient's plan and the particular pharmacy. Each of these factors varies significantly among plans and pharmacies--even within the same health insurance company or PBM receiving the same --------------------------------------------------------------------------- manufacturer rebate--creating confusion and frustration for patients. Given the complexity in the system and number of factors that impact out-of- pocket costs, every part of the health-care system has an obligation to work to solve this problem. I am grateful that this Committee--and others--are taking a holistic approach to collecting information both on what is causing the problem for patients, and also on solutions to address patient access and affordability without undermining the incentives and rewards for scientific risk-taking and discovery that are the hallmark of the United States ecosystem and economy. I am here today to share Sanofi's story, the actions we have taken to improve patient access and affordability, and our ideas about what more can be done. ii. sanofi actions to improve patient access and affordability As a global health-care leader, Sanofi has a long-standing commitment to promoting health-care systems and policies that make our treatments accessible and affordable to patients in need. We believe we can play an important role in the development of constructive solutions that will benefit both patients and the health-care system as a whole. I will address some of our ongoing initiatives and recommendations for solutions in my testimony. Sanofi's ultimate goal, detailed below, is to encourage a transition to a value- driven health-care system that provides incentives for continued improvements in patient care while increasing access and affordability. Given the complexities of the current system, changes must be approached thoughtfully, with a focus on establishing processes that will both enable affordable access to treatment and protect innovation in an era of potentially transformative scientific advancements. Sanofi is--and will continue to be--an industry leader in helping to address this challenge. While many factors, including decisions affecting patient out-of-pocket spending and insurance coverage, are influenced or controlled by others in the health-care system, including other manufacturers, we recognize that there are actions we can take to help improve access and affordability for patients. For our part, we recognize that we must price our medicines transparently and according to their value, while at the same time contributing to broader solutions that improve patient outcomes and the financial sustainability of the U.S. health-care system. Policy changes are required across the entire health care system. But we are not waiting for systemic change to arrive before taking action. Sanofi has adopted a variety of approaches to work within the current system to improve access and affordability for patients. Whether it has been launching new medicines in multiple sclerosis and rheumatoid arthritis at disruptively low prices, limiting price increases to an external benchmark of overall medical spending, or lowering the net price of a medicine, Sanofi has approached the challenge of access and affordability not with words, but with actions. iii. sanofi pricing principles and actions Two years ago, Sanofi announced our progressive and industry- leading pricing principles to help stakeholders understand our pricing decisions and to advance a more informed discussion of issues related to the pricing of medicines.\2\ --------------------------------------------------------------------------- \2\ See https://www.sanofi.us/-/media/Project/One-Sanofi-Web/ Websites/North-America/Sanofi-US/Home/corporateresponsibility/ Prescription_Medicine_Pricing_2019.pdf. These principles include a pledge to keep annual list price increases at or below the projected U.S. National Health Expenditure (NHE) growth rate, an estimate of medical spending calculated by the Centers for Medicare and Medicaid Services (CMS) and often used as a measure of healthcare inflation. These principles apply to all of our prescription medicines if a pricing decision results in more than a $15 annual increase in the price of the medication. In addition, we committed to making both our average aggregate list and net price changes across our portfolio transparent to help illustrate how revenue accrues to Sanofi versus other parts of the pharmaceutical supply --------------------------------------------------------------------------- chain. In 2018, all of our price increases were consistent with our policy, as are all pricing actions we have taken in 2019. Across our entire portfolio of medicines, the average aggregate list price increase was 4.6 percent while the average aggregate net price--that is, the actual price paid to Sanofi--declined by 8.0 percent. The declining average aggregate net price in 2018 represents the third consecutive year the amount that health plans and PBMs pay Sanofi for our medicines has declined. U.S. Portfolio Annual Average Aggregate Price Changes * ------------------------------------------------------------------------ Average Aggregate List Average Aggregate Net Year Price Price ------------------------------------------------------------------------ 2016 4.0% Increase 2.1% Decrease ------------------------------------------------------------------------ 2017 1.6% Increase 8.4% Decrease ------------------------------------------------------------------------ 2018 4.6% Increase 8.0% Decrease ------------------------------------------------------------------------ * Average aggregate across Sanofi's prescription product portfolio. Specific to insulin, the average aggregate net price across all Sanofi insulin products has declined over the past four years. For our entire insulin portfolio, the average net price is 25 percent lower today than it was in 2012.\3\ --------------------------------------------------------------------------- \3\ Based on internal review of pricing actions and payer contracting. [GRAPHIC(S) NOT AVAILABLE IN TIFF FORMAT] In addition to our pledge to limit price increases in the U.S., Sanofi's pricing policy includes a commitment to transparency in how we price new medicines coming to the market for the first time. When we set the price of a new medicine, we hold ourselves to a rigorous and structured process that includes consultation with external --------------------------------------------------------------------------- stakeholders and considers four factors: (1) A holistic assessment of value, including (a) clinical value and outcomes, or the benefit the medicine delivers to patients, and how well it works compared to a standard of care; (b) economic value, or how the medicine reduces the need--and therefore costs--of other health care interventions; and (c) social value, or how the medicine contributes to quality of life and productivity. Our assessments rely on a range of internal and external methodologies, including health technology assessment (HTA) approaches and other analyses that help define or quantify value and include patient perspectives and priorities. (2) Similar treatment options available or anticipated at the time of launch in order to understand the competitive landscape within the disease areas in which the medicine may be used. (3) Affordability, including the steps we must take to promote access for patients and contribute to a more sustainable system for payers and health-care delivery systems. (4) Unique factors specific to the medicine at the time of launch. For example, we may need to support ongoing clinical trials to provide additional critical information on the value of the product (e.g., longer-term outcomes studies), implement important regulatory commitments, or develop sophisticated patient support tools that improve care management and help decrease the total cost of care. Using this approach, Sanofi has launched a number of highly innovative products at prices well below the competition, some even before our principles were officially adopted. In 2012, Sanofi launched Aubagio ', a medicine used to treat relapsing forms of MS, at a list price more than 25 percent below the other approved oral MS medication on the market at the time. In 2017, we launched Kevzara ', a second line medication used to treat certain types of rheumatoid arthritis (RA), at a list price 30 percent below other leading treatments for RA. After completing a head to head study against the market-leading anti-TNF, Kevzara was found superior in RA patients. In 2017, we launched Dupixent ', the first drug of its kind for moderate to severe atopic dermatitis, specifically within the cost-effectiveness range provided by the Institute for Clinical and Economic Review (ICER) of $37,000, compelling the Chief Medical Officer for a leading PBM to say ``this is how pricing should work.'' While we have concerns about ICER's methodology in many of their drug reviews, our willingness to work with ICER is further demonstration to our commitment to price our medicines based on the value they provide with consideration of input from a third-party analysis. In 2018, we launched Admelog ' at the lowest list price of any mealtime insulin. In February 2019, Sanofi and Regeneron announced that Praluent ' will be made available at a new reduced U.S. list price. Beginning in early March, new U.S. National Drug Code (NDC) option will be available at approximately 60 percent less than the original list price for the drug. This action follows our earlier announcement in March 2018, when Sanofi and Regeneron committed to lowering the U.S. net price for payers in return for reducing burdensome access barriers for appropriate patients.\4\ Sanofi and Regeneron took the additional step of announcing a new NDC to further assist patients, particularly in Part D, who still face cost-sharing linked to the list price, and who were thus not helped by the earlier net price reduction. With the new lower-priced Praluent, most Medicare Part D patients are expected to save as much as $345 per month, depending on their insurance plan. --------------------------------------------------------------------------- \4\ See http://www.news.sanofi.us/2018-03-10-Sanofi-and-Regeneron- announce-plans-to-make-Praluent-R-more-accessible-and-affordable-for- patients-with-the-greatest-health-risk-and-unmet-need. With the right incentives in the system, our approach to setting launch prices for these new medicines would have had the effect of ensuring affordable access for patients. Unfortunately, because of the way the U.S. health care system is currently constructed, our experience has shown that pricing medicines at lower list prices has failed to result in adequate access or affordability for most patients. For instance, since Dupixent was launched, rebates have been required in most cases to secure access for patients. Despite the responsible list price and subsequent rebates, 8 commercial and 2 Medicaid plans nevertheless implemented a step edit requiring patients to try immunosuppressant therapy first before using Dupixent. They implemented this step edit notwithstanding the fact that immunosuppressant therapy is not FDA approved for use in atopic dermatitis and is referenced as a worst-case scenario for patients in practice guidelines due to its questionable benefit-risk profile. iv. sanofi's insulin products: a case study We feel a special obligation to address the pressing issues around access and affordability of insulin products. In my time as CEO, Sanofi has made a concerted effort to improve both system sustainability and patient affordability in our approach to our portfolio of insulin products, which includes six different products to meet individualized patient needs. And it is important to note the evolution and innovation of insulin, as we are often asked if anything has changed in the last 100 years that warrants pricing action. Sanofi's groundbreaking discovery of insulin glargine, and its development of a novel pre-filled disposable injection pen to deliver insulin glargine, have profoundly improved the lives of millions of patients living with diabetes in the United States and worldwide. Sanofi's insulin glargine drug products are sold under the trade names Lantus ', Lantus SoloSTAR ', Toujeo SoloSTAR ', and Toujeo Max SoloSTAR ', each of which represents a significant leap forward in the treatment of diabetes. Sanofi has been awarded patents for its innovative technologies on each of these products. These novel drug products began with Sanofi's discovery of insulin glargine. Despite having ``insulin'' in its name, Sanofi's insulin glargine is markedly different from prior insulin products, which had a relatively short duration of action and required patients to inject themselves multiple times a day and wake up at night for injections in order to control blood glucose levels. Each injection of prior insulin products caused a sharp spike in the patient's insulin levels, which could cause symptoms of low blood sugar ranging from shakiness and confusion to, in the extreme, coma or death. Injections also had to be timed before every meal, disrupting patient's lives, sleep times, and ability to eat with friends and family. As such, the consistent goals of insulin therapy over the last century have included reducing the frequency of insulin administration and flattening the post- administration peak of insulin in the bloodstream. Prior attempts to achieve these goals included cumbersome mechanical pumps that had to be worn on the body for constant infusion, and NPH insulin, which had an intermediate duration of action but still caused a pronounced peak in insulin levels. Glargine changed all of that. Sanofi scientists, in a remarkable feat of protein engineering, succeeded in fundamentally altering the human insulin molecule at the amino acid level, changing its pharmacological characteristics to give patients a steady release of insulin with just a single daily administration. Unlike anything that came before it, glargine forms tiny solid crystals upon injection that dissipate over time to provide a flatter, stable, long-lasting effect that mimics the flat profile of insulin release from a healthy pancreas and reduces the risks caused by low blood sugar. The once-daily administration of glargine also proved a significant boon to patient lifestyles. Insulin is also an excellent example of list prices not reflecting the actual prices paid by insurance companies, and out-of-pocket costs that continue to rise despite lower net prices. The net price of our insulin product Lantus ', for example, has fallen over 30 percent since 2012; yet, over this same period, average out-of-pocket costs for patients with commercial insurance and Medicare--before the benefit of any Sanofi financial assistance program--has risen 60 percent. v. sanofi's financial assistance programs Our commitment to affordability for patients extends beyond responsible launch pricing, limited price increases, and transparency. We offer a suite of traditional and innovative patient assistance programs to enable appropriate patient access and to help patients afford the Sanofi medicines prescribed to them. We publicize our programs in a number of ways to ensure patients and providers are aware of our offerings, including through advertising online, on television, as well as in provider office settings and at pharmacies. As noted previously in my testimony, rising out-of-pocket costs for patients is a complex problem with many causes. In some cases, access issues are linked to lack of insurance. But having insurance is no longer a guarantee of affordable care, and Sanofi believes it is also critical to address the needs of patients who may be exposed to excessive cost-sharing based on insurance plan design or other deficiencies in the system. Because patient situations are different, we have carefully tailored our assistance programs for insulin products to meet a variety of patient needs: Commercially insured patients qualify for our co-pay assistance program, which reduces the financial burden for insulin products. Through this program, over 90 percent of participating commercially insured patients pay either $10 or $0 per month for their Sanofi-manufactured insulin products. Last year, our co-pay assistance programs for commercially insured patients provided more than 400,000 eligible patients with $342 million in patient savings. For diabetes patients who do not qualify for one of our co- pay assistance programs, we created the Insulins ValYOU Savings Program in 2018. The purpose of this program is to provide relief for those patients who currently pay high variable retail prices for insulin and do not qualify for other assistance programs. Through this program, eligible individuals can access all Sanofi insulins for $99 per 10 mL vial or $149 for a pack of SoloStar pens, approximately a one-month supply of insulin,\5\ at a discount of up to 60 percent discount below the list price, resulting in potential savings of up to $3,000 per year. There are no income requirements and the program is available at U.S. pharmacies. Last year (its first year), the program resulted in $6.2 million in patient savings. --------------------------------------------------------------------------- \5\ Patients with type 1 diabetes require insulin replacement with both long-acting (basal) and mealtime (bolus) insulin. An average adult with type 1 diabetes who weighs 70 kg (155 pounds) should be taking anywhere from 0.5-1.0 u/kg/day--depending upon activity levels, and meal choices. Using the higher daily dose of 1.0 u/kg/day, this patient would need a total of 70 units/day of insulin, of which approximately half should be mealtime (bolus) insulin and half should be long-acting (basal) insulin. For this average patient, one vial of long-acting (basal) and one vial of mealtime (bolus) insulin could provide a monthly supple of insulin. Many patients with type 2 diabetes require long-acting (basal) insulin only. Our internal data shows the average daily dose is approximately 45 units per day, resulting in a monthly requirement of 1350 units of long-acting (basal) insulin per month. Lantus SoloSTAR ' pack contains 1500 units of insulin (5 pens x 300 units per pen) and Toujeo SoloSTAR ' pack contains 1350 units of insulin (3 pens x 450 units per pen). For the average patient with type 2 diabetes, the ValYOU Savings Program would meet the monthly insulin requirement with one payment of $149. Patients on lower doses of Lantus may opt for the 10ml vial, which would meet the monthly insulin requirement with one payment of $99. For eligible low-income patients, Sanofi offers many of our medicines, including our insulin products, at no charge through its Sanofi Patient Connection patient assistance program. We are proud that, in 2018, more than 93,000 patients participated in the Sanofi Patient Connection program, receiving free --------------------------------------------------------------------------- medicine valued at $508 million. While Sanofi alone cannot eliminate the issue of patient affordability, no matter how comprehensive or innovative our patient assistance programs, we believe that our efforts can make a meaningful difference for many patients. We are committed to maintaining these programs and raising awareness of these options to the patients who need them. vi. policy proposals Over the past few years, we have led by example and made decisions to help improve access and affordability for patients. I am here today to tell you that I know our actions, while well-intentioned, have not been enough. I hope we can all agree on market-based policy solutions that will incentivize a high-value, sustainable health-care system that improves the affordability of innovative medicines in the U.S. Based on our experience, targeting list price controls alone will not be sufficient to address patient access and affordability. That is why the solution to drug pricing must include protections for patients, tying responsible pricing to both access and affordability for patients. There are obviously a variety of ways to accomplish this, and Sanofi could support any number of options that align to our core principles: (1) The U.S. should continue to maintain a strong ecosystem for innovation. As such, any policy proposals should strictly avoid directly and artificially controlling the price of medicines, either through price controls set by the Federal Government, or worse, outsourcing that decision to foreign governments. Policy proposals that we believe would fundamentally undermine the unique innovation ecosystem of the United States include reference pricing, importation, or price controls set by CMS. Based on our experience, these approaches may be effective at controlling budgets for central payers but come at a steep cost for patients--namely limiting access to innovative treatments. Additionally, given that the U.S. is the world's leader in science and innovation--and the jobs that come with it--these approaches pose additional risks to the U.S. economy and future scientific discovery. Finally, and most importantly, given the differences between systems, these approaches may do little to improve access and affordability for patients. As we have experienced, within the current system, declining prices for payers or new treatments priced at responsibly lower list prices are no guarantee that those actions will translate to affordability or access for patients. (2) Changes to the pricing system must be holistic, and the majority of benefits should accrue to patients. As noted previously, simply enacting price controls--either set by a State, Federal, or foreign government--will not solve the problem of access and affordability for patients. We believe system incentives need to change to encourage smaller list price increases, or even list price reductions, by requiring health plans to cover those medicines that meet these standards at an affordable co-pay level and only allow access restrictions consistent with the label and accepted evidence- based best clinical practice. If policies are enacted that solely target the list price of medicines without these common-sense patient protections, our shared goal of lowering drug costs--for both government and patients while maintaining the engine of innovation in the United States to bring new innovative medicines to patients will not be fully achieved. To appropriately accomplish this objective, Sanofi is willing to trade price for access and affordability and share accountability for offsetting the financial impact on the Medicare programs. Sanofi supports and recommends several policy solutions to incentivize responsible pricing behavior. To ensure that these changes do not create a windfall for manufacturers or health plans and PBMs, Sanofi recommends applying these policies only to medicines that satisfy certain limits on price increases. This approach will shift the current incentives in the system to reward ``good'' behavior in a manner that truly helps patients. Several of the solutions outlined below are also priorities for Chairman Grassley, Ranking Member Wyden and other members of this committee and I look forward to the opportunity to work with you on advancing these and other policy initiatives: First, reducing out-of-pocket costs for patients is our top priority. As we have experienced, limiting list price of medicines alone is not sufficient to fully solve this problem. Sanofi has identified a number of ways to effectively reduce out-of-pocket costs for consumers and broadly supports tradeoffs between price and access to help patients, including: Implementation of the Anti-Kickback Safe Harbor rebate proposed rule in a manner that directly lowers out-of-pocket costs for patients without creating loopholes that would undermine the proposed rule's intent. Requiring a portion of the discounts and rebates paid by manufacturers to reduce costs for patients at the pharmacy counter. Changing government price reporting rules and the Anti- Kickback statute in a manner that would promote value-based contracting. Implementing an annual out-of-pocket cap for Medicare beneficiaries. Allowing manufacturers to offer co-pay assistance to Medicare beneficiaries. Changing or clarifying government price reporting rules to make it easier to reduce list prices on medicines that have been on the market for a long time--namely by (1) making clear that the government pricing metrics for the new, lower list price drug do not have to be averaged with the metrics for older, higher list price drug and (2) permitting a company to treat the new lower price drug as a new product for purposes of Medicaid rebate calculations, which will help to link the rebate liability for the new drug to the new drug's lower price as opposed to the higher price for the old drug. Second, Sanofi supports policies that cultivate a highly competitive free market system and rewards the type of entrepreneurial risk-taking necessary to the discovery and development of life-saving new medicines. A key element of that system is a strong and predictable intellectual property system. However, after a reasonable period of time--which I believe is already reflected in U.S. law--generic and biosimilar medicines should quickly enter the market to offer long-term access at lower costs. To help accomplish these goals, Sanofi supports: Legislation that promotes competition, such as the CREATES Act, and prohibitions on ``reverse payment'' agreements. While some changes may be needed to avoid unintended consequences, we support moving forward with policies that limit manufacturers' ability to unfairly avoid competition. At Sanofi, we make product supply available to generic and biosimilar manufacturers developing data necessary for FDA applications for their products. We do this in a timely manner and on reasonable terms. Increased system-wide transparency, which would improve competition across health care by making relevant information available to patients and policymakers. Providing more information about what is driving costs in the system and how money is flowing through the system will allow for increased competition and better-informed decision making. Policies like the SPIKE Act, which appropriately include a threshold for reporting to incentivize responsible pricing behavior and the C-THRU Act, are potential approaches. vii. conclusion I look forward to having a productive conversation about the complexities of the current prescription drug pricing system and proposals to improve affordable patient access to high quality, innovative medications to drive optimal health outcomes. Thank you for the invitation to speak with you today and I look forward to working with you. ______ Questions Submitted for the Record to Olivier Brandicourt, M.D. Questions Submitted by Hon. Chuck Grassley Question. The Department of Health and Human Services' proposed rule, ``Fraud and Abuse; Removal of Safe Harbor Protection for Rebates Involving Prescription Pharmaceuticals and Creation of New Safe Harbor Protection for Certain Point-of-Sale Reductions in Price on Prescription Pharmaceuticals and Certain Pharmacy Benefit Manager Service Fees,'' envisions that drug manufacturers will offer up-front discounts rather than the back-end rebates that are now commonly provided. Some observers argue that a 1996 court case called into question whether manufacturers could offer up-front discounts, resulting in today's rebate-based system. I've heard differing opinions as to whether the issues related to the initial court case are still relevant. If the HHS proposed rule is finalized, can you assure the committee that your company will offer up-front discounts? If not, why? Answer. As the question notes, one of the practical implications of the Proposed Rule is to incentivize a shift from back-end rebate payments to up-front discounts that are passed through at the point-of- service to the patient (at least in part). We understand that some in the health care industry have raised concerns that the nation's antitrust laws, specifically the Robinson-Patman Act, and long-running antitrust litigation involving drug manufacturers, wholesalers, and pharmacies could prevent or reduce discounting under a pricing structure without rebates. But, the Robinson-Patman Act focuses on price discrimination--involving any dimension of price--and it does not distinguish between up-front discounts and rebates. In addition, the referenced litigation, In re Brand Name Prescription Drugs Antitrust Litigation, did not result in any change in the ability of a prescription drug manufacturer to offer an up-front discount. Consequently, because Sanofi's view is that the antitrust laws apply equally to up-front discounts and back-end rebates, we do not believe that they present any impediment to offering up-front discounts to patients at the point of sale. Sanofi is committed to working with other stakeholders to lower patient out-of-pocket costs, and the company will carefully review any final rule issued by HHS regarding the Anti-Kickback Statute and its safe harbor regulations--with the goal of providing point-of-sale discounts to patients in a compliant manner to help lower patient out-of-pocket costs. Question. Please describe how you expect your company to respond to the HHS proposed rule to eliminate safe harbor protection for back-end rebates in Medicare Part D that is referenced above if it is finalized. Assuming you are confident that antitrust laws do not prevent your company from offering up-front discounts, specifically, do you envision that your company lowers the list price of a drug to the current after- rebate net price, offer discounts equal to the current rebate amount, or a combination of both? Answer. Sanofi is committed to working with other stakeholders to lower patient out-of-pocket costs, and the company will carefully review any final rule issued by HHS regarding the Anti-Kickback Statute and its safe harbor regulations--with the goal of providing point-of- sale discounts to patients in a compliant manner to help lower patient out-of-pocket costs. With respect to list price, if (1) the proposed changes to the anti-kickback statute safe harbors were codified, and (2) Congress implemented similar changes to the commercial insurance market, Sanofi would lower the list prices of its prescription medications for products in competitive categories for which there is currently a material difference between list price and net price on the assumption that patient access and affordability would be improved. Sanofi also supports policy changes that would de-link other payments in the pharmaceutical supply chain from list price. We support extending the intent behind the anti-kickback statute safe harbor proposed rule to the commercial market so that incentives are aligned across the marketplace. Together, we believe these changes would facilitate Sanofi's ability to lower our list prices. However, we recommend a step-wise approach, implementing changes to the commercial market after the safe harbor rule is implemented on January 1, 2020. Such an approach would provide an opportunity for stakeholders and the government to identify unintended consequences, and address them, prior to extending these policies to the commercial market. We want to ensure that the new system achieves its goal of improving affordability for patients. For instance, CMS should monitor and evaluate how the new system affects formulary access, utilization management, and patient cost-sharing, particularly with respect to medicines with a lower list price. We also have concerns that changes to the rebate system may lead to new fees, which simply require manufacturers to pay previous rebate values in new ways, rather than creating savings for patients. Without a better understanding of how these policy changes ultimately would affect the competitive marketplace, patient access, and affordability, we are unable to quantify the amount of up-front discounts or any potential list price reduction. Question. To what extent are the back-end rebates your company currently offers contingent on the amount of market share realized for your drugs as a result of Part D plan formulary placement and other techniques? Answer. Sanofi negotiates rebates with PBMs and Part D plans to secure better formulary position for our products, which in turn provides the best possible access and cost sharing for the majority of Medicare Part D beneficiaries. When evaluating what level of rebates to offer, Sanofi considers the potential business impact of such arrangements. Question. Please provide a breakdown of percentage of sales that go to each payer (including Medicare, Medicaid, private pay, other) and a similar percentage by volume of the total number of each drug compared to total volume. Please provide this data for the most recent year available. Primary Care Products Percentage of Sales by Payer Channel \1\ ---------------------------------------------------------------------------------------------------------------- Channel ---------------------------------------------------------------------------------------------------------------- FSS Others Product Commercial Medicare Medicaid Tricare 340B \2\ Institutional \3\ ---------------------------------------------------------------------------------------------------------------- Lantus 25% 36% 10% 0% 5% 19% 4% ---------------------------------------------------------------------------------------------------------------- Toujeo 47% 39% 7% 0% 4% 2% 0% ---------------------------------------------------------------------------------------------------------------- Soliqua 100/33 77% 15% 3% 0% 3% 1% 0% ---------------------------------------------------------------------------------------------------------------- Apidra 16% 1% 66% 0% 8% 7% 2% ---------------------------------------------------------------------------------------------------------------- Admelog 0% 0% 91% 0% 9% 0% 0% ---------------------------------------------------------------------------------------------------------------- Multaq 24% 57% 2% 0% 3% 12% 2% ---------------------------------------------------------------------------------------------------------------- Praluent 22% 32% 1% 0% 2% 5% 38% ---------------------------------------------------------------------------------------------------------------- \1\ Based on gross sales. \2\ This category includes the VA, DOD, and other purchases through Sanofi US's Federal Supply Schedule (FSS). \3\ This category includes Hospital/GPO, Long-Term Care, Outpatient, and Staff Model. Percentage by Volume by Payer Channel ---------------------------------------------------------------------------------------------------------------- Channel ---------------------------------------------------------------------------------------------------------------- Product Commercial Medicare Medicaid Tricare 340B FSS Others Institutional ---------------------------------------------------------------------------------------------------------------- Lantus 25% 36% 10% 0% 5% 19% 4% ---------------------------------------------------------------------------------------------------------------- Toujeo 47% 39% 7% 0% 4% 2% 0% ---------------------------------------------------------------------------------------------------------------- Soliqua 100/33 77% 15% 3% 0% 3% 1% 0% ---------------------------------------------------------------------------------------------------------------- Apidra 16% 1% 67% 0% 7% 7% 2% ---------------------------------------------------------------------------------------------------------------- Admelog 0% 0% 91% 0% 9% 0% 0% ---------------------------------------------------------------------------------------------------------------- Multaq 24% 57% 2% 0% 3% 12% 2% ---------------------------------------------------------------------------------------------------------------- Praluent 22% 32% 1% 0% 2% 5% 38% ---------------------------------------------------------------------------------------------------------------- Specialty Care Products Percentage of Sales by Payer Channel \4\ ---------------------------------------------------------------------------------------------------------------- Channel ---------------------------------------------------------------------------------------------------------------- Commercial/ Medicaid/VA / Non-Contracted Product Managed Care Medicare DOD/Tricare PHS/340B Sales ---------------------------------------------------------------------------------------------------------------- Cerdelga 0% 12% 6% 4% 78% ---------------------------------------------------------------------------------------------------------------- Cerezyme 0% 15% 15% 22% 48% ---------------------------------------------------------------------------------------------------------------- Aldurazyme 0% 6% 29% 23% 42% ---------------------------------------------------------------------------------------------------------------- Fabrazyme 0% 13% 10% 26% 51% ---------------------------------------------------------------------------------------------------------------- Myozyme 0% 18% 15% 31% 36% ---------------------------------------------------------------------------------------------------------------- Thyrogen 0% 4% 5% 25% 66% ---------------------------------------------------------------------------------------------------------------- Caprelsa 0% 6% 10% 0% 84% ---------------------------------------------------------------------------------------------------------------- Aubagio 47% 33% 11% 2% 7% ---------------------------------------------------------------------------------------------------------------- Lemtrada 0% 35% 10% 41% 14% ---------------------------------------------------------------------------------------------------------------- Kevzara 69% 15% 4% 3% 9% ---------------------------------------------------------------------------------------------------------------- Dupixent 75% 9% 6% 3% 7% ---------------------------------------------------------------------------------------------------------------- Eloctate 0% 5% 33% 37% 25% ---------------------------------------------------------------------------------------------------------------- Alprolix 0% 5% 27% 39% 29% ---------------------------------------------------------------------------------------------------------------- Jevtana 0% 70% 1% 30% 0% ---------------------------------------------------------------------------------------------------------------- Zaltrap 0% 0% 0% 0% 100% ---------------------------------------------------------------------------------------------------------------- Elitek 0% 15% 1% 7% 77% ---------------------------------------------------------------------------------------------------------------- Mozobil 0% 25% 6% 45% 24% ---------------------------------------------------------------------------------------------------------------- Thymoglobulin 0% 0% 0% 4% 96% ---------------------------------------------------------------------------------------------------------------- \4\ The data used to derive this information is contracted sales data. Because many of these products are purchased through non-contracted sales, Sanofi has a limited view regarding through which channels these products are purchased. Percentage by volume by channel results in similar percentages to percentage by sales so a separate chart is not provided. Question. Do your companies hire consultants or lobbyists to promote products at State Medicaid Pharmacy and Therapeutics Committees? To whom do you disclose advocacy activities surrounding State Medicaid programs, if at all? Answer. Sanofi does not hire external consultants or lobbyists to advocate for coverage of our products at State Medicaid Pharmacy and Therapeutics Committees. Sanofi employees do attend State Medicaid Pharmacy and Therapeutics Committees meetings. Relevant advocacy activities to support Medicaid access and coverage of our medicines, if any, are disclosed to States in accordance with individual State laws. Question. Please describe how the costs of patient assistance programs are accounted for within your company's financial statements. Please also describe the types of market information, such as prescribing and use patterns, that your company collects from different types of patient assistance programs and patient hub services. Answer. Within Sanofi's financial statements, Sanofi includes the administrative costs of the company's co-pay assistance programs, other point-of-sale programs, and free drug patient assistance program (Sanofi Patient Connection) in the ``Selling and general expenses'' line item. For co-pay assistance and other point-of-sale programs, Sanofi records the pharmacy reimbursement amount paid by the company as a reduction in sales. Sanofi records free product provided through Sanofi Patient Connection within ``Cost of Sales.'' Sanofi Care North America, the 501(c)(3) operating foundation that donates free product to Sanofi Patient Connect, records the free goods as a ``Contribution'' when received from Sanofi and as a ``Donation'' when donated to Sanofi Patient Connection. With regard to market information associated with its patient assistance programs and hub services, Sanofi generally collects data that aids in the efficient administration and operation of these programs. For example, the vendors operating Sanofi Patient Connection and the hubs collect information provided by patients on enrollment forms, including patient and provider demographic information, patient insurance information, patient diagnosis, and prescription information necessary to evaluate patient program eligibility and/or administer the program. (Sanofi does not itself receive patient protected health information except in very limited circumstances, such as when a patient reaches out to Sanofi directly when they do not agree with their patient assistance eligibility determination or when Sanofi monitors vendor calls for compliance with company policies and procedures.) With respect to Sanofi Patient Connection, Sanofi does not use this information for purposes other than administering the patient assistance program. With respect to hub services, in addition to using this information to administer hub programs, Sanofi may use this data to develop market and business insights. With respect to Sanofi's point-of-sale patient assistance programs, Sanofi also receives anonymized program utilization data, including information about patient out-of-pocket costs, the average amounts that Sanofi reimburses pharmacies through the program, abandonment rates, dispensing pharmacies, and the prescribers writing the prescriptions associated with program utilization. This information is used to administer the program. Sanofi may also use this data to develop market and business insights. Question. Please provide a list of all contributions since January 1, 2014, that your company has made to any tax exempt organizations working on issues related to drugs within your product lines, including but not limited to patient groups, disease awareness groups, medical or professional societies, universities or hospitals, industry associations or leagues. For each contribution, please provide the name of the organization that received the donation, the date the donation was made, the amount of the donation, and a description of the purpose of the contribution (i.e., was the contribution for the general fund, a specific purpose to a specific program, or continuing medical education). Please also note whether the contribution was unrestricted or restricted; if it was restricted, please explain all restrictions. Finally, if your company maintains a foundation or other separate charitable arm, please provide the name of all such entities, and list all donations made from that entity or entities. Answer. In the attached documents, we have provided information for the period January 1, 2015 through December 31, 2018 regarding payments made by Sanofi US to tax-exempt organizations.\5\ The information is provided in a number of documents consistent with how Sanofi maintains this information. In some cases, this information may be over-inclusive and include non-tax exempt organizations (e.g., contributions for independent medical education into both non-profit and other entities). The information includes contributions and sponsorships to various tax- exempt health-care-oriented organizations, including patient groups. The information also includes contributions made for independent medical education grants, and to teaching hospitals for investigator- sponsored trials and for physician fellowship payments. On March 8, 2018, Sanofi acquired Bioverativ, Inc., a biopharmaceutical company focused on therapies for hemophilia and other rare blood disorders. The attached documents also describe the monetary contributions to tax exempt organizations made by Bioverativ since March 8, 2018. --------------------------------------------------------------------------- \5\ These contributions may not relate to particular drug products. Sanofi US supports programs and initiatives of external, independent, not-for-profit organizations that align with Sanofi US's corporate vision and values. These organizations are generally healthcare- oriented and focus on one or more therapeutic areas in which Sanofi US is actively involved. The attached information focuses on Sanofi US entities that manufacture and sell drug products and does not include entities that manufacturer and sell consumer health products or vaccines. Contribution information prior to 2015 is archived in databases and systems that Sanofi does not currently maintain and which are not easily accessible. The information available does not distinguish between restricted and unrestricted grants. With respect to any foundations or charitable arms of Sanofi, from January 1, 2014 through the end of 2017, Sanofi maintained an entity called Sanofi Foundation of North America, a 501(c)(3) nonprofit operating foundation that was closed at the end of 2017. Donations made from that entity are included in the attachments described above. Currently, Sanofi maintains an entity called Sanofi Cares North America, which is a 501(c)(3) nonprofit operating foundation that makes donations of Sanofi products free of charge to eligible financially- needy uninsured and underinsured patients through a program known as the Sanofi Patient Connection. Sanofi Cares North America also donates product to five non-governmental organization partners for the purpose of emergency disaster relief--Americares, DirectRelief, Heart to Heart International, MAP International, and Project Hope, and to approximately one hundred summer camps with 501(c)(3) status for --------------------------------------------------------------------------- children with diabetes. Question. Pay for delay agreements cost consumers and taxpayers billions in higher drug costs every year. The FTC has gone after drug companies that enter into these settlements where the brand pays the generic company to keep its lower cost alternative off the market. I'm the lead Republican sponsor of S. 64, the ``Preserve Access to Affordable Generics and Biosimilars Act,'' which would help put an end to these deals. Do you agree that these pay-off agreements keep drug costs high for patients because they delay competition? Answer. With respect to patent litigation, Sanofi believes it is inappropriate to presume that any settlement of patent litigations related to pharmaceutical products is anticompetitive. Patent settlements are often the most efficient and effective way to resolve disputes regarding patented drugs, and they often lead to the earliest appropriate entry of generic products into the market, which benefits patients. In fact, settlements permit entry of a generic alternative into the market earlier than expiration of the relevant branded product's patent. Each patent litigation and potential settlement presents unique factors and must be considered individually and in light of the relevant circumstances. Question. Has your company ever entered into these kinds of settlements with a generic company? Answer. No, Sanofi does not enter into ``pay for delay'' or ``reverse payment'' agreements that prohibit generic drug or biosimilar development after the expiration of a patent. Sanofi has reached settlements in patent infringement cases, and these agreements have allowed the generic company to commercialize its product before the expiration of the branded product's patent(s). Question. Do you support the pay for delay bill? Answer. We support the intent behind this legislation to promote competition, including prohibitions on ``reverse payment'' agreements. However, we have significant concerns with the way that this bill is drafted, and therefore we do not support this particular legislation. We believe that it is inappropriate to make settlements of patent litigations presumptively illegal or to classify such settlements as anticompetitive. Such settlements can be the most efficient and effective way to resolve legitimate disputes regarding patented drugs, and they often lead to the earliest appropriate entry of generic products into the market, which in turn benefits patients. As stated above, each patent litigation and potential settlement presents unique factors and must be considered individually and in light of the relevant circumstances. Additionally, we have concerns that this bill could apply retroactively to agreements entered into after June 17, 2013. For clarity and certainty in the marketplace, any new legislation governing the settlement of patent litigation should apply prospectively only. rebate traps/walls Question. I'm increasingly concerned about the effect of so-called ``rebate traps'' or ``rebate walls'' on patients' access to quality, lower cost medicine. I understand there is ongoing litigation challenging these practices as anti-competitive. Does your company engage in the bundling of rebates over multiple products? If so, why? And what benefit does the consumer gain from that? Answer. Sanofi offers discounts in bundled sales arrangements only in limited circumstances. For example, Sanofi may offer bundled discounts on its products Toujeo' and Lantus' to ensure that both products attain a formulary position that benefits patients. This is especially important because the products may serve patients with different medical needs. Question. Does your company view these practices as anticompetitive or harmful to patients' access to quality, lower cost medicine? Answer. Sanofi prioritizes patient access to medications at a reasonable cost. Sanofi's arrangements with individual PBMs or insurers promote this goal by maintaining stability of supply at affordable prices. In competitive drug markets, Sanofi may enter into arrangements with particular PBMs or insurers that permit Sanofi to further reduce its prices on one or more medications in exchange for greater certainty regarding the amount of those medications it will sell over a specified term. These arrangements promote patient access to quality, affordable medications, are procompetitive, and comply with the antitrust laws. Moreover, in competitive drug markets Sanofi's ability to ensure patient access to affordable medications is affected both by PBMs and insurers (who may have considerable negotiating leverage over manufacturers) and by other manufacturers (who may respond to competition from Sanofi in a variety of ways). While some manufacturers may respond by building ``rebate walls'' or ``rebate traps'' around their products, Sanofi shares the Committee's concern about practices that are harmful to patients' access to quality, affordable medication. Question. If a policy were adopted to eliminate rebates, or to require that rebate savings be passed on to the consumer, would that in and of itself solve the issue of rebate ``traps'' and ``walls''? And would consumers benefit from such a policy? Answer. The elimination of safe harbor protection for rebates would remove incentives for manufacturers to attempt to influence formulary placement through such discounts. It is also possible that competitive products would be launched at lower list prices and more readily incorporated into formularies on the basis of their clinical benefits in a world without rebates. This would benefit the system overall, including consumers. drug pricing Question. When setting the list price of a drug, does your company consider regulatory costs or compliance? If so, how specifically do those factors affect the list price of a drug? Please provide at least one specific example, if applicable, from your current product portfolio. Answer. The primary factors that Sanofi considers in setting list price include the value of the product, the competitive environment, patient affordability and access, investment in further product development or needs to reinvest in R&D more generally. In certain limited cases, Sanofi also will consider regulatory costs when setting the list price of a product. These factors may be considered, for example, where ongoing clinical trials are needed for a particular therapy or when the FDA mandates a Risk Evaluation and Mitigation Strategy (``REMS'') for a product--such as with Sanofi's drug Lemtrada. Sanofi does not, however, consider our routine and ongoing regulatory compliance efforts within the cost of our products. Rather, those efforts are considered part of Sanofi's operating costs. Question. When setting the list price of a drug, does your company consider the risk of liability or litigation? If so, how specifically do those factors affect the list price of a drug? Please provide at least one specific example, if applicable, from your current product portfolio. Answer. When conducting its pricing analysis for a new drug, Sanofi does not specifically consider the risk of liability or litigation associated with such product. ______ Questions Submitted by Hon. Pat Roberts Question. What role do you see Value Based Arrangements (VBAs) playing in the effort to reduce prescription drug costs? What potential do these arrangements have to find the ``sweet spot'' between controlling costs to patients and encouraging innovation of new drugs? How can VBAs help lower what patients pay out-of-pocket? Can Congress do more to allow for and encourage the use of VBAs? Answer. Sanofi believes that encouraging an environment that is supportive of value-based arrangements would help promote drug affordability, increase patient access to medicines, and improve patient adherence and outcomes. Although there are different types of these agreements, value-based contracts generally tie prices and payments to the value of a particular prescription drug product--while potentially reducing patient out-of-pocket costs and providing patients with better access to the most innovative drug products. A manufacturer could, for example, condition payment for a product on its success in meeting a predefined clinical outcome, and this type of arrangement could make drugs more affordable and lower healthcare costs throughout the system. Facilitating value-based arrangements also could encourage new drug innovation, control costs for such new products, and recognize the full value of complex and personalized treatments. Nevertheless, despite the promise of these arrangements, industry stakeholders--including manufacturers and payers--need better legal and regulatory clarity. For example, we support the creation of a safe harbor from Anti-Kickback Statute liability to protect value-based agreements. We also are supportive of any legislation that would facilitate value-based arrangements and protect them from legal enforcement, such as the Patient Affordability, Value, and Efficiency Act (PAVE Act). ______ Questions Submitted by Hon. John Cornyn Question. We continue to hear that rebates negotiated off of the list price of a drug are both good and bad. Pharmacy benefit managers and plans have argued that rebates are used to lower premiums across the board and that it is the best way to seek a price concession on otherwise expensive drugs. Your industry argues that these payers are insisting on higher rebates that can only be achieved by raising list prices. But patients often lose under this system, with out of pocket costs being tied to list price. Insulin patients appear to be routinely impacted by this perversity in the system. Please explain to the committee how your company would reduce list prices if rebates were no longer a part of the equation? What assurance can you provide that you would in fact lower your prices? What actions should be taken to ensure that patients are actually seeing the benefits of lower out of pocket costs? Answer. If (1) the proposed changes to the anti-kickback statute safe harbors were codified, and (2) Congress implemented similar changes to the commercial insurance market, Sanofi would lower the list prices of its prescription medications for products in competitive categories for which there is currently a material difference between list price and net price on the assumption that patient access and affordability would be improved. Sanofi also supports policy changes that would de-link other payments in the pharmaceutical supply chain from list price. We support extending the intent behind the anti-kickback statute safe harbor proposed rule to the commercial market so that incentives are aligned across the marketplace. Together, we believe these changes would facilitate Sanofi's ability to lower its list prices. However, we recommend a step-wise approach, implementing changes to the commercial market after the safe harbor rule is implemented on January 1, 2020. Such an approach would provide an opportunity for stakeholders and the government to identify unintended consequences, and address them, prior to extending these policies to the commercial market. We want to ensure that the new system achieves its goal of improving affordability for patients. For instance, CMS should monitor and evaluate how the new system affects formulary access, utilization management, and patient cost-sharing, particularly with respect to medicines with a lower list price. We also have concerns that changes to the rebate system may lead to new fees, which simply require manufacturers to pay previous rebate values in new ways, rather than creating savings for patients. Without a better understanding of how these policy changes ultimately would affect the competitive marketplace, patient access, and affordability, we are unable to quantify the amount of any potential list price reduction. With respect to actions that should be taken to ensure patients are seeing the benefit of lower out-of-costs, we support legislation that would incentivize manufacturers to lower list prices by connecting better patient access and affordability to such pricing actions. Question. If rebates are driving high list prices for drugs as drug manufacturers' claim, why do you think that Part B drugs, which have no PBM rebates, are also seeing significant price increases? Whose fault is that? Answer. Sanofi considers a variety of factors when setting or raising its list prices. These factors include the value of the product, the competitive environment, patient affordability and access, investment in further product development or needs to reinvest in R&D more generally. Within this framework, any list price increase is made consistent with our pricing principles, including our commitment to limit the total annual increase to a level at or below the NHE projected growth rate, as estimated by CMS. Although we agree that one factor in price increases across the industry may be the increased demand for rebates at the PBM and health plan level, that is not the only factor. In fact, Sanofi believes that reducing incentives for high prices throughout the supply chain by delinking payments from list price would have a meaningful impact on price and patient costs. This is true, for example, with group purchasing organizations (GPOs) that negotiate pricing for Part B providers. As with PBMs, these GPOs negotiate rebates and administrative fees that are linked to the list price of the product. These structures thus create the same misalignment of interests as in the PBM setting. It is important to note, as well, that the current average sales price (ASP)-based system for Medicare Part B works to moderate price growth because reimbursement reflects the weighted average of discounts given to providers, payers, and other commercial purchasers. This means that the Medicare program and its beneficiaries benefit from the discounts health plans and providers negotiate on these drugs. Due to this market-based competition, ASP reimbursement rates often are substantially lower than list prices. biosimilar competition/insulin Question. Biosimilars have been much anticipated as a solution to the drug pricing crisis. In particular, the FDA is moving to make insulin a biologic that would be subject to biosimilar competition in the future. But we are hearing from all of you that the biosimilar market doesn't work and the benefit of these cheaper but equally effective alternatives are really not available to U.S. patients. Can a biosimilar version of insulin be part of the solution for diabetes patients? If so, what changes need to be made to the system so that patients and the taxpayer can realize the benefit of biosimilars? (Merck gave up on pursuing a biosimilar to Sanofi's Lantus.) \6\ --------------------------------------------------------------------------- \6\ https://www.fiercepharma.com/pharma/merck-ditches-biosimilar- lantus-but-will-ease-path-for-mylan-s-rival-insulin-product. Answer. Sanofi believes that biosimilars currently--and will continue to--result in increased competition. In fact, this type of competition has grown among insulin manufacturers in recent years, and we expect that it will continue to lower prices for patients with diabetes. For example, in 2016, Eli Lilly introduced a follow-on biologic to Sanofi's drug Lantus. Additionally, in 2018, Sanofi introduced Admelog, a follow-on biologic of Humalog, at a list price that was 15% lower than the reference product. Mylan also is developing a second follow-on insulin glargine that references Lantus, and Sanofi is developing a biosimilar insulin aspart, a rapid-acting insulin, which we expect to introduce in 2021. Sanofi expects that the already highly competitive diabetes drug market will become increasingly robust over time--including with the anticipated introduction of --------------------------------------------------------------------------- interchangeable biosimilar basal and rapid acting insulins. There are changes already in place that will help patients and taxpayers realize the benefit of biosimilars. Specifically, in March 2020, certain biologics that are currently regulated as drugs, including long acting insulins, will be regulated as biologics and therefore will be subject to the existing biosimilars pathway. We expect the change in insulin regulation to spur the continued development of substitutable or interchangeable insulin products, and to increase competition in this space generally. ______ Questions Submitted by Hon. Todd Young re-evaluating business strategies in foreign countries Question. Since taking office, President Trump has made reducing drug prices one of his highest priorities--and has repeatedly spoken about his frustration with the U.S. subsidizing the costs of pharmaceuticals for the rest of the world. He has gone so far as to issue proposals, like the International Pricing Index (IPI) Model, in an attempt to bring down prescription drug prices. With the increased scrutiny of the industry and of the drug supply chain as a whole in the United States, have any of your companies re- evaluated your business strategy in foreign countries? If not, then why? Answer. No, Sanofi has not reevaluated its business strategy in foreign countries. Other countries have implemented systems, such as price controls or reference price regimes, to directly and artificially regulate the price of medicines. In our experience, there is not an opportunity for Sanofi to negotiate prices with these foreign government payers. Sanofi's only choice is to accept the government- mandated price, or to not sell the pharmaceutical in that country, which not only hurts a company financially, but more importantly harms patients. We note that, although these systems may be effective at controlling budgets for central payers, they come at a steep cost for patients, including severe access restrictions and rationing. For instance, one analysis of the report released to justify the International Pricing Index found that 96 percent of new cancer medicines are available in the U.S. compared to 71 percent in the United Kingdom and 65 percent in France.\7\ --------------------------------------------------------------------------- \7\ http://phrma-docs.phrma.org/download.cfm?objectid=0C19E240- 19C7-11E9-87D20050569A4 B6C. As a Sanofi specific example, Dupixent is the first drug to be approved for moderate to severe atopic dermatitis (eczema) in the US. FDA granted Breakthrough Therapy designation to Dupixent as preliminary clinical evidence indicated that ``the drug may demonstrate substantial improvement over available therapy on clinically significant endpoint(s).'' Dupixent was approved by FDA in March 2017 under Priority Review, which means that FDA's goal is to take action on this application within 6 months (compared to 10 months under standard review). Within 24 hours of FDA approval, Sanofi shipped orders for Dupixent to be made available to U.S. patients. In contrast, Health Canada approved Dupixent in November 2017. However, Dupixent is still --------------------------------------------------------------------------- not publicly reimbursed in Canada. Question. If a proposal, like IPI, were implemented, would it force your companies to potentially ``walk away from the negotiating table when other countries demand low prices subsidized by America's seniors,'' as HHS Senior Advisor for Drug Pricing Reform John O'Brien has said? Answer. In our experience, there is not an opportunity for manufacturers to negotiate with a government. Sanofi's only choice is to accept the government-mandated price, or to not sell the product in that country, which, as noted above, not only hurts Sanofi financially, but more importantly harms patients. Question. What are some of your ideas on how we can ensure Americans aren't shouldering the full cost of pharmaceuticals? Answer. While we understand the concern that Americans are shouldering more than their fair share of the cost of innovation in the pharmaceutical sector, the list price discrepancy between the U.S. and other countries is due, in primary part, to the different health care systems. Because Sanofi pays significant rebates to payers and PBMs, the difference between the price in other developed countries and the net price in the U.S. is not nearly as large. Sanofi's top priority is reducing out-of-pocket costs for patients. We believe that there need to be reforms to the current system to better align incentives, including market-based approaches to pricing that promote competition and ensure patients have affordable and sustainable access to innovative medicines. Currently, payers and PBMs inconsistently pass through the growing savings that they receive from increased negotiated rebates. Accordingly, despite increasing rebates and lower net prices, out-of-pocket costs for many patients have continued to grow. Sanofi supports policies that pass PBM and payer rebate savings to patients at the pharmacy counter through lower copays and coinsurance. Sanofi would also support policies that would incentivize responsible pricing by tying smaller list price increases, or even list price reductions, to both access and affordability for patients. foreign countries' pricing and reimbursement Question. President Trump and Secretary Azar have both repeatedly described their frustrations with ``foreign freeloading'' of U.S. drugs in the last year. ``When foreign governments extort unreasonably low prices from U.S. drug makers, Americans have to pay more to subsidize the enormous cost of research and development. . . . It's unfair and it's ridiculous, and it's not going to happen any longer.'' Do you agree that because of foreign countries' pricing and reimbursement systems, U.S. patients and innovators are shouldering the burden for financing medical advances? Answer. It is true that the U.S. is the main engine in pharmaceutical and biotechnology innovation in the world. Although U.S.-based manufacturers manage clinical trials globally, there are substantially more research and development dollars invested in the U.S. than in any other country. To illustrate, in 2015, PhRMA member companies spent over $47 billion in domestic R&D and only $12 billion in R&D abroad. For Sanofi, in 2018, we spent nearly $7 billion on R&D globally--a substantial portion of which in the U.S.--and we expect that our annual R&D spend will be consistent through 2021. These investments in research, in turn, create significant and important job opportunities in the United States. However, it is important to note that while other countries' pricing and reimbursement systems may help to contain costs in those countries, they come at a steep cost for patients, including severe access restrictions and rationing. For instance, one analysis of the report released to justify the International Pricing Index found that 96 percent of new cancer medicines are available in the U.S. compared to 71 percent in the United Kingdom and 65 percent in France.\8\ Moreover, the list price discrepancy between the U.S. and other countries is due, in part, to the different health-care systems. Because Sanofi pays significant rebates to payers and PBMs, the difference between the price in other developed countries and the net price in the U.S. is not nearly as large. --------------------------------------------------------------------------- \8\ http://phrma-docs.phrma.org/download.cfm?objectid=0C19E240- 19C7-11E9-87D20050569A4 B6C. Question. How do foreign countries' pricing and reimbursement --------------------------------------------------------------------------- systems affect our prescription drug costs? Answer. Pricing and reimbursement systems in other countries do not affect how Sanofi prices its medicines in the United States. Consistent with our pricing principles, when Sanofi sets the price of a new medicine in the U.S., we hold ourselves to a rigorous and structured process that includes consultation with external stakeholders. In our view, an objective measure of a new product's value considers the benefit to patients, compared to a standard of care; the reduced need-- and therefore costs--of other health-care interventions; and any increase in quality of life and productivity. We believe our pricing reflects these factors. We also consider factors such as the affordability for patients and any unique factors specific to the medicine, like the need to support ongoing clinical trials, implement important regulatory commitments, or develop sophisticated patient support tools that improve care management and help decrease the total cost of care. Additionally, under our pricing principles, we have pledged to limit price increases at or below the National Health Expenditure (NHE), which is the projected annual health-care spending growth rate as estimated by CMS. Question. Are foreign governments taking note of the concerns being raised by the Trump administration and have they responded in any way? Answer. Sanofi is not aware of any responses by foreign governments to U.S. drug pricing policy proposals advanced by the Trump administration. Question. Has there been any noticeable change in any of our trade agreements since these concerns have been raised by the Trump administration? Answer. Sanofi is not aware of any such changes. medicaid closed formulary proposals Question. In an attempt to bring down drug costs, various States have been exploring whether to exclude certain drugs from their Medicaid program. For example, the State of Massachusetts recently asked CMS for permission to create a closed formulary where the State Medicaid program would pick at least one drug per therapeutic class. CMS denied their waiver request citing violation of Federal law, but this proposal does bring up important questions on how to contain drug prices in State Medicaid programs. If the principles of the Medicare Part D program--including the necessary patient protections--were applied to State Medicaid programs, do you think it would lower drugs costs while ensuring access to patients? Answer. The Part D program encourages strong competition in the marketplace, including by providing beneficiaries with choice of different plans and encouraging drug manufacturers to compete for formulary position to support broad access to their medicines (in part by securing lower cost-sharing obligations for patients in preferred formulary tiers). By contrast, State Medicaid programs are obligated, as a condition of a manufacturer's participation in the Medicaid Drug Rebate Program, to cover company's products (subject to certain narrow exceptions). Consequently, although we believe that increased competition in the Medicaid program could help to lower drug prices, including if Medicaid implemented certain of the Part D program's principles, it is not immediately clear how these changes would further enhance patient access. medicaid ``best price'' Question. In the Trump administration's Blueprint, they suggested that because drug manufactures have to give Medicaid the ``best price'' on drugs, there is no incentive to offer deeper discounts to other payers--both government and commercial--than what is already offered under the Medicaid Drug Rebate Program. Does the Medicaid ``best price'' requirement encourage manufacturers to increase initial prices? Answer. The Medicaid Rebate Act, and CMS's corresponding rules, require drug manufacturers to pay rebates to the State Medicaid Programs for units of drug dispensed to their beneficiaries. Medicaid ``Best Price'' generally is defined as the lowest price offered to commercial purchasers in the United States, and it is one of two key metrics used for setting the level of rebates that manufacturers must pay to each state Medicaid program for Medicaid beneficiary utilization. Best Price does not, therefore, reflect a price point at which manufacturers sell products to Medicaid, and Sanofi does not view the Medicaid Best Price requirements as encouraging manufacturers to set higher initial prices. However, Medicaid Best Price considerations are a factor in assessing whether to offer higher rebate amounts to our commercial (Best Price-eligible) customers. Question. What, if any, changes would you suggest we make to the program? Answer. With regard to the Medicaid Drug Rebate Program and the determination of Best Price, the Trump administration's Pricing Blueprint highlights the impediments that exist under current rules with regard to value-based discounting arrangements. Sanofi would like to pursue more innovative product discounting strategies--including arrangements in which we would stand behind the value or outcomes that our products provide to patients and to the healthcare system generally. But, current Medicaid rebate calculation rules regarding bundled discount arrangements, and the manner in which manufacturers must account for discounts that are incurred over long periods of time, present significant obstacles to adopting these arrangements. If the rules for the Medicaid Drug Rebate Program were amended to permit manufacturers to exclude certain appropriately-structured value-based discounts from their Best Price calculation, it is likely that Sanofi could adopt more innovative value-based discount contracts, and that these arrangements in turn could result in significant savings for patients and the system. outcomes-based contracts Question. In almost all of your testimonies, you highlight your support of outcomes-based contracts and how we need to be shifting our system toward that approach. How will these contracts lower drug costs for patients in both the near term and long-term? How will they lower overall health-care costs for our Federal programs? What have the preliminary results looked like so far? Answer. Sanofi believes that encouraging an environment that is supportive of value-based arrangements would help promote drug affordability, increase patient access to medicines, and improve patient adherence and outcomes. Specifically, value-based arrangements tie prices and payments to value while reducing patient out-of-pocket costs and providing patients with better access to the most innovative drug products. For example, value-based arrangements can be premised upon the effectiveness of a manufacturer's product, which may help to secure payer coverage for new and innovative therapies. Where payment to a manufacturer is conditioned on the value or clinical outcomes of a product, value-based arrangements also may help to improve patient cost-sharing challenges. Additionally, value-based arrangements could encourage new drug innovation while controlling costs for such new products by aligning the price of the drug to the value the drug brings to the patient. Recently, Sanofi has executed value-based contracts related to Soliqua 100/33, Praluent, and Kevzara. These arrangements are in their nascent stages, and we do not have sufficient information to assess the results. Despite the promise of these and similar arrangements, Sanofi strongly believes that better legal and regulatory clarity would facilitate greater proliferation of value-based contracts. For example, we support the creation of a safe harbor from Anti-Kickback Statute liability to expressly protect value-based agreements. We also are supportive of legislation that would remove Best Price-barriers to value-based contracts, such as the Patient Affordability, Value, and Efficiency Act (PAVE Act). transparency/point of sale Question. In almost all of your testimonies, you express your support for the Trump Administration's proposal to allow manufacturers to provide PBMs up-front discounts that are passed onto patients at the point-of-sale. Do you feel like this proposal will make the transactions within the drug supply chain more transparent? If so, would this transparency bring down drug costs--overall and for specialty drugs? Answer. Because the proposed rule would require manufacturer discounts to be provided at the pharmacy counter, the proposal will facilitate increased transparency with respect to the arrangements between manufacturers and PBMs, and with respect to the discounts manufacturers offer on their medicines. We believe such increased transparency would result in lower patient costs. However, Sanofi believes that HHS's proposal does not go far enough in creating the kind of systemic change needed to create a more transparent drug supply chain throughout the entire U.S. health-care system. We believe that increased, system-wide transparency, that appropriately protects competitively sensitive information, would improve competition by making relevant information available to patients and policymakers. Providing more information about what is driving costs in the system, and taking steps to curtail misaligned incentives related to the flow of money through the system, for instance through legislation like the C-THRU Act, would allow for increased competition and better-informed decision making. the relationship between wholesalers and manufacturers Question. When talking about the pharmaceutical supply chain, a lot of focus has been placed on the Pharmacy Benefit Manager. But there's another side of the equation that I'd like to ask about. How do wholesalers negotiate pricing with manufacturers? What impact does this have on drug costs? What incentives or disincentives do they have to contain price increases? Answer. Wholesalers do not typically negotiate pricing with manufacturers. Wholesalers are merchant-middlemen in the supply chain, and they generally facilitate the efficient distribution of drugs and biologicals to end customers (such as pharmacies or clinics). While Sanofi may offer a prompt pay discount to wholesalers, wholesalers generally purchase product at Wholesale Acquisition Cost (i.e., list price) and they facilitate the acquisition of products by end purchases--frequently at prices that are negotiated between Sanofi and the end purchaser. If wholesalers sell to end purchasers at a loss based on the negotiated price, wholesalers will issue a ``chargeback'' to the manufacturer for the difference. In addition, Sanofi pays service fees to wholesalers to operationalize this distribution and chargeback process, and those fees typically are based on a percent of WAC. As with fees paid to PBMs, Sanofi's view is that flat pricing for wholesaler administrative services could exert downward pressure on drug prices by delinking list price from fee payments. ______ Questions Submitted by Hon. Ron Wyden proposed rebate rule Question. As has been done in many other settings, drug manufacturers said during the hearing that one reason list prices for drugs are high is that pharmaceutical benefit managers (PBMs) demand larger and larger rebates in order for the drug to receive favorable placement on a formulary. You and your colleagues who testified during the hearing stated if the administration's proposal on changes to the anti-kickback safe harbor for pharmaceutical rebates took effect, your company would likely lower list price. Like many Oregonians, I am skeptical drug manufacturers would voluntarily lower their prices. Therefore, would you support legislation that would (1) make similar changes the administration has put forward related to Part D and Medicaid managed care, (2) change the rebate system in a similar way to the proposal for the commercial market, and (3) require drug makers to lower the list price of their drugs equal to the amount of rebates provided today? Answer. If (1) the proposed changes to the anti-kickback statute safe harbors were codified, and (2) Congress implemented similar changes to the commercial insurance market, Sanofi would lower the list prices of its prescription medications for products in competitive categories for which there is currently a material difference between list price and net price on the assumption that patient access and affordability would be improved. Sanofi also supports policy changes that would de-link other payments in the pharmaceutical supply chain from list price. We support extending the intent behind the anti-kickback statute safe harbor proposed rule to the commercial market so that incentives are aligned across the marketplace. Together, we believe these changes would facilitate Sanofi's ability to lower our list prices. However, we recommend a step-wise approach, implementing changes to the commercial market after the safe harbor rule is implemented on January 1, 2020. Such an approach would provide an opportunity for stakeholders and the government to identify unintended consequences, and address them, prior to extending these policies to the commercial market. We want to ensure that the new system achieves its goal of improving affordability for patients. For instance, CMS should monitor and evaluate how the new system affects formulary access, utilization management, and patient cost-sharing, particularly with respect to medicines with a lower list price. We also have concerns that changes to the rebate system may lead to new fees, which simply require manufacturers to pay previous rebate values in new ways, rather than creating savings for patients. Without a better understanding of how these policy changes ultimately would affect the competitive marketplace, patient access, and affordability, we are unable to quantify the amount of any potential list price reduction. We support legislation that would incentivize manufacturers to lower list prices by connecting better patient access and affordability to such pricing actions. The U.S. market-based approach to drug pricing has been successful in reducing net prices, but in the current system, that value is not being passed on to patients. We expect that the reforms we note above would address that issue while preserving a market-based approach that promotes competition and ensures patients have affordable and sustainable access to innovative medicines. medicaid drug rebate program Question. The Medicaid Drug Rebate Program (MDRP) requires manufacturers to provide a basic rebate and an additional inflationary rebate for both brand and generic drugs. The inflationary rebate is an increasingly substantial part of total rebates due in large part to large increases in drug prices that exceed inflation. Under current law, this inflationary rebate is capped at 100 percent of Average Manufacturer Price (AMP). This is the case even when manufacturers continue to raise their prices well above inflation. Please provide a list of all of your pharmaceutical products that have reached the Medicaid AMP rebate cap in any of the 20 quarters from January 1, 2014 through December 31, 2018. For each drug listed in response to question 1, please also provide a list of which quarters and years each drug hit the cap. Answer. Sanofi takes steps to ensure that it complies with all applicable laws related to the Medicaid Drug Rebate Program, including that it is paying rebates to the state Medicaid programs in accordance with law. Sanofi sells NDCs in 29 product families for which it pays Medicaid rebates at 100 percent of AMP. Respectfully, Sanofi's view is that the detailed information requested by this question is confidential and proprietary. We would be happy to work with the Committee to provide this information in a way that mitigates against competitive harms that could arise from public disclosure of this information. medicaid drug rebate program compliance Question. I am concerned about recent reports and legal settlements surrounding drug manufacturers' failure to comply fully with the requirements of the MDRP. For example, an analysis by the U.S. Department of Health and Human Services Office of Inspector General found that between 2012 and 2016 taxpayers may have overpaid by as much as $1.3 billion for 10 potentially misclassified drugs. That is why I introduced the Right Rebate Act with Chairman Grassley to prevent drug manufacturers from manipulating Medicaid to increase their profits. However, I continued to be concerned about oversight and manufacturer compliance with the requirements of the Medicaid Drug Rebate Program. Accordingly, please describe the following: Your company's current compliance plan and procedures used to ensure compliance with the requirements of the Medicaid Drug Rebate Program including internal audits or other checks you use to identify compliance vulnerabilities. Answer. Sanofi takes steps to ensure that it complies with all applicable laws related to its participation in the Medicaid Drug Rebate Program (MDRP). These steps include, for example, documenting Medicaid rebate calculation methodologies, processes, and reasonable assumptions as appropriate. Sanofi's government price reporting personnel also hold weekly meetings with the Sanofi legal department, including with support from outside counsel as needed, to ensure that compliance questions are discussed and addressed in a timely manner. Sanofi's MDRP compliance is tested through several audits, including biannual Sarbanes-Oxley Act audits, biannual external audits, conversations with an external consultant government pricing advisory team, and annual calculation audits of Average Manufacturer Price and Best Price. Question. Any past or ongoing issues of non-compliance. Answer. Given the complexity of the MDRP and applicable law and guidance, Sanofi routinely reviews its calculation methodologies and reasonable assumptions. In the normal course of business, questions may arise as to specific Sanofi compliance processes for the MDRP. When such questions arise, Sanofi takes prompt steps to engage with CMS about appropriate next steps, including a restatement of any of the components of the Medicaid rebate calculation if needed. Such restatements are administrative in nature and expressly contemplated by the CMS regulations. Question. Any corrective actions taken to address identified problems or issues of noncompliance with the MDRP and how such steps were communicated to the Centers for Medicare & Medicaid Services. Answer. As noted above, in the event that Sanofi identifies any compliance questions that it believes warrant review by CMS, Sanofi promptly engages with CMS. This may occur, for example, in the event of statutory or regulatory changes, or if CMS releases new sub-regulatory guidance. Question. Any steps taken to improve compliance and ensure that all Medicaid drug rebates owed to the federal government and the states are paid in full. Answer. Sanofi's government price reporting team routinely works with in-house and outside counsel regarding compliance with the Medicaid Drug Rebate Act and CMS rules. As part of this continuing compliance, the company assesses its calculation processes and reasonable assumptions for purposes of calculating Average Manufacturer Price, Best Price, and Unit Rebate Amount. In certain cases, moreover, Sanofi engages directly with CMS to seek the agency's view of Sanofi's reasonable assumptions or compliance processes. In any instance in which Sanofi would determine that the State Medicaid Programs were underpaid rebates, Sanofi would engage with CMS to determine the appropriate way forward, including restating pricing metrics and paying additional rebates to the States. bonus payments tied to specific drugs Question. I am concerned by the potential for employee financial incentives to encourage high launch prices and price increases for prescription drugs. Is your salary, bonus or other compensation tied to sales or revenue targets of a single product your company sells? Has it ever been? If yes, please state the product or products to which your salary, bonus or other compensation was tied. Is your salary, bonus or other compensation tied to either revenue or net income of the company as a whole? Has it ever been? If yes, please explain what assumptions about price increases are used when the compensation committee sets revenue or net income goals. Does the compensation committee provide any guidance to executives in regards to the amount of revenue that the company will generate from price increases versus volume growth? Answer. The Sanofi board of directors, acting on the recommendation of the Compensation Committee, sets the compensation for the chief executive officer (CEO). That compensation structure includes fixed compensation, variable compensation, options, performance shares, and benefits in kind. Sanofi's overall compensation policy is designed to motivate and reward performance by ensuring that a significant portion of compensation is contingent on the attainment of financial, operational, and extra-financial criteria aligned with the corporate interest and with the creation of shareholder value. Therefore, in 2017 (the most current year in which public information is available), as Sanofi's CEO, Dr. Brandicourt was eligible for up to 250 percent of his target fixed compensation in variable compensation. Several factors are considered in determining his variable compensation; 40 percent is based on financial indicators, and 60 percent is based on specific individual objectives, including external growth, product launches, operational transformation, organization and staff relations, and new product pipeline. Dr. Brandicourt's compensation package also includes equity-based compensation, which is medium-term and aims to align the interests of the CEO with those of the shareholders and other stakeholders. In 2017, he received a set number of options to subscribe for shares, based on performance conditions measured over a 3-year period, as well as performance shares based on business net income, return on assets, and total shareholder return. net prices Question. In your testimony, you stated, ``we have increased transparency by providing, each year, information about our list and net prices across all of our medicines,'' and that ``in 2018, the average aggregate list price increase across all Sanofi medicines in the U.S. was 4.6 percent . . . the price actually paid to Sanofi, declined by 8 percent. So declining average aggregate net price in [2018] represents the third consecutive year in which the amount paid by payers across all of our medicines went down.'' Please describe how the company's year-over-year aggregate net price is calculated. Please also specifically address the following questions. Answer. Sanofi calculates the aggregate net price as follows: Brand net sales are divided by common units for the appropriate period. This amount--``net price per unit''--is then compared to the prior period. This amount establishes any increase or decrease for the brand for the period being calculated. Once this is done for all brands, the increase/decrease is weighted by gross sales (i.e., volume) to show the aggregate net price impacts for Sanofi's portfolio of medicines. Question. How many products are included in the calculation of the average net price change? What was the median net price change? Answer. This analysis is done on 79 separate products, covering 76 brands. Some brands have multiple product forms with different prices; Sanofi separates these product forms when calculating average net price. The median net price change in 2018 was zero percent across all products. Removing products with no net price change, the median net price change in 2018 is -1.0%. This calculation is not weighted by gross sales. Question. Is net price weighted? If so, how? For example, in determining the aggregate net price does the company assign different weights to different products based on volume or other factors? Are ``on patent'' and ``off patent'' drugs weighted identically? Are other statistical weights used or are all products treated equally? Answer. All products are weighted by gross sales (i.e., volume), irrespective of whether Sanofi has any current patents related to the product. No other statistical weights were used. Question. Does the figure that you provided during your testimony account for U.S. prices, international prices, or both? Generally speaking, when your company reports net price changes, does it differentiate between U.S. and international prices? Answer. The data Dr. Brandicourt provided regarding average aggregate list price and average aggregate net price accounted for U.S. prices. Sanofi's annual pricing report \9\ and related reporting on net price consider U.S. prices only. --------------------------------------------------------------------------- \9\ https://mediaroom.sanofi.com/-/media/Project/One-Sanofi-Web/ Websites/Global/Sanofi-COM/mediaroom/pdf/2019/ Prescription_Medicine_Pricing_2019.pdf. Question. Please list the five drugs your company sold in the U.S. that had the greatest year-over-year net price increase in 2018, noting the increase for each drug by dollar figure and percentage. Please list the five drugs your company sold in the U.S. that had the lowest year- over-year net price increase (and/or the greatest decrease) in 2018, noting the increase (or decrease) for each drug by dollar figure and --------------------------------------------------------------------------- percentage. Products with Greatest Average Net Price Increases in 2018 \10\ ------------------------------------------------------------------------ YOY Percentage YOY U.S. Dollar Product Change Change by Unit ------------------------------------------------------------------------ Renvela \11\ 40% $1.00 ------------------------------------------------------------------------ Imovax \12\ 15% 30.10 ------------------------------------------------------------------------ Caprelsa \13\ 12% 1,536.60 ------------------------------------------------------------------------ Hectorol \14\ 11% 0.03 ------------------------------------------------------------------------ Zaltrap \15\ 9% 0.60 ------------------------------------------------------------------------ \10\ We have excluded products that were discontinued/divested in 2018, have no sales in 2018, or if the reason for net price increase was due to changes in prior accounting estimates or assumptions (as opposed to changes in rebates and discounts). \11\ Sanofi did not take any list price increases on Renvela in 2018. The net price increase is due to (1) changes in prior accounting estimates/assumptions, and (2) increasing use of generics in class, resulting in (i) change in the mix of business, and (ii) a reduction in rebate payments. \12\ Sanofi took a 5-percent list price increase on Imovax in 2018. \13\ Sanofi took a 5-percent list price increase on Caprelsa in 2018. \14\ Sanofi reduced the list price of Hectorol by 47 percent in October 2018. The net price increase was due to a reduction in rebate payments. \15\ Sanofi did not take any list price increases on Zeltrap in 2018. Products with Greatest Average Net Price Decreases in 2018 \16\ ------------------------------------------------------------------------ YOY Percentage YOY U.S. Dollar Product Change Change by Unit ------------------------------------------------------------------------ Renvela AG -74% -1.57 ------------------------------------------------------------------------ Zolpidem CR -68% -0.26 ------------------------------------------------------------------------ Leflunomide -63% -0.59 ------------------------------------------------------------------------ Clolar -48% -894.26 ------------------------------------------------------------------------ Priftin -26% -0.54 ------------------------------------------------------------------------ \16\ We have excluded products that were discontinued/divested, have no sales in 2018, or if the reason for net price decline was due to changes in prior accounting estimates or assumptions (as opposed to changes in rebates and discounts). Question. For 2018, what was the average net price change in the U.S. market for (1) drugs with no competition, (2) drugs with only branded competition, and (3) drugs with generic competition? Answer. (1) Drugs with no competition:\17\ 0.0%. --------------------------------------------------------------------------- \17\ We define a product as having no competition if there are no other products in the therapeutic class. (2) Drugs with only branded competition:\18\ -2.1%. --------------------------------------------------------------------------- \18\ We define a product as having only branded competition if there is no generic, follow-on biologic, or biosimilar product in the therapeutic class. (3) Drugs with AB-rated generic/follow-on biologic/biosimilar --------------------------------------------------------------------------- competition: -13.5%. Question. In its most recent pricing report, Sanofi states that it ``increased the price of 35 of our 76 prescription medicines'' in the United States. This statement appears to be in regards to list price. How many of these medicines had their net price increase? Answer. Seventeen of the 35 prescription medicines with list price increases also had average net price increases. Question. In its most recent pricing report, Sanofi states that ``in 2018, 55 percent of our gross sales were given back to payers as rebates, including $4.5 billion in mandatory rebates to government payers and $7.3 billion in discretionary rebates.'' For each product, please disclose the gross sales and the amount of rebates paid. Answer. Product-level rebate information is confidential and proprietary information for competitive reasons and falls within the definition of ``trade secret'' under the Trade Secrets Act, 18 U.S.C. Sec. 1905, Exemption 4 of the Freedom of Information Act, 5 U.S.C. Sec. 552(b)(4), and the Defend Trade Secrets Act of 2016, 18 U.S.C. Sec. 1836. Public disclosure of this information would cause significant harm to Sanofi and Sanofi's customers, and competitors would gain unfair competitive advantage if they were to obtain this information through public disclosure. We note that congressional and executive agencies have historically expressed concern that disclosure of such information could inhibit competition. For example, in 2007 when then-chairman Waxman asked several Medicare Part D prescription drug plans (``PDPs'') to submit to the House Oversight and Government Reform Committee information on the negotiated price discounts, rebates and other price concessions that they obtained from drug manufacturers, the CBO issued a report concluding that public disclosure of that information could reduce the rebates that PDPs received and thus raise Medicare costs.\19\ Specifically, the CBO found that the disclosure of rebate data could cause the variation in rebates among purchasers to decline. Because PDPs generally secure rebates that are somewhat larger than the average rebates observed in commercial health plans, the disclosure of Part D rebates to competitors could create pressure to reduce those rebate amounts, which in turn could increase costs for the Medicare program and, on average, the costs for Medicare beneficiaries.\20\ Specifically, the CBO found that the disclosure of rebate data could cause the variation in rebates among purchasers to decline. Second, CBO concluded that disclosure of rebates could facilitate tacit collusion among the manufacturers of competing brand-name drugs, reducing the rebates to PDPs and thus increasing net drug prices.\21\ Similarly, the Federal Trade Commission (``FTC'') has cited concerns regarding the anti-competitive effects of disclosing net pricing and other price- sensitive information. In the context of the healthcare industry generally, the FTC noted: --------------------------------------------------------------------------- \19\ CBO, Letter to the Hon. Joe Barton and the Hon. Jim McCrery (March 12, 2007), available at https://www.cbo.gov/system/ files?file=2018-10/03-12-drug-rebates.pdf; see also CBO, ``Increasing Transparency in the Pricing of Health Care Services and Pharmaceuticals'' (June 5, 2008), available at https://www.cbo.gov/ sites/default/files/110th-congress-2007-2008/reports/06-05- pricetransparency.pdf. \20\ Id., at 3. \21\ Id., at 4. [Price transparency] can actually harm competition and consumers. Some types of information are not particularly useful to consumers, but are of great interest to competitors. We are especially concerned when information disclosures allow competitors to figure out what their rivals are charging, which dampens each competitor's incentive to offer a low price, or increases the likelihood that they can coordinate on higher prices.\22\ --------------------------------------------------------------------------- \22\ FTC, Office of Policy Planning, ``Price Transparency or TMI?'' (July 2, 2015), available at https://www.ftc.gov/news-events/blogs/ competition-matters/2015/07/price-transparency-or-tmi. Moreover, in describing its concerns about a New York state bill that would have required pharmacy benefit managers (``PBMs'') to disclose their rebate arrangements with drug manufacturers, the FTC explained that disclosure of this information could ``facilitate collusion, raise prices, and harm the patients the Bill is supposed to protect.'' \23\ The FTC further explained that, without knowledge of such competitor rebate information: --------------------------------------------------------------------------- \23\ FTC, Office of Policy Planning, Bureau of Competition and Bureau of Economics, Letter to Hon. James L. Seward re: New York Senate Bill 58, at 5 (March 31, 2009), available at https://www.ftc.gov/sites/ default/files/documents/advocacy--documents/ftc-staff-comment- honorable-james-l.seward-concerning-new-york-senate-bill-58-pharmacy- benefit-managers-pbms/v090006newyorkpbm.pdf. [M]anufacturers have powerful incentives to bid aggressively for formulary position, because preferential formulary treatment may yield increased sales. Unprotected disclosures thus may raise the price that New York consumers pay for pharmaceutical coverage by undermining competition among pharmaceutical companies for preferred formulary treatment.\24\ --------------------------------------------------------------------------- \24\ Id. See, also, FTC, Office of Policy Planning, Bureau of Competition, and Bureau of Economics, to Assemblyman Greg Aghazarian re: California Assembly Bill No. 1960 (September 7, 2004) (concluding that, if manufacturers learn the exact amount of the rebates offered by their competitors through required PBM disclosures, then tacit collusion among manufacturers is more feasible, which may lead to higher prices for PBM services and drugs), available at https:// www.ftc.gov/sites/default/files/documents/advocacy_documents/ftc- comment-hon.greg-aghazarian-concerning-ca.b.1960-requiring-pharmacy- benefit-managers-make-disclosures-purchasers-and-prospective- purchasers/v040027.pdf. For these reasons, in public settings, we have provided rebate information at an aggregate level only, to prevent reverse engineering by competitors to learn our net pricing information for specific products. We would be happy to work with the committee to provide this information in a way that mitigates against competitive harms that --------------------------------------------------------------------------- could arise from public disclosure of this information. ______ Questions Submitted by Hon. Robert Menendez Question. When new products enter the market, do drug companies set high initial prices and then provide deep rebates in order to gain access to insurance plan's formularies? Answer. We can only speak for Sanofi. Consistent with our pricing principles, when Sanofi sets the price of a new medicine, we hold ourselves to a transparent, rigorous, and structured process that includes consultation with external stakeholders. In our view, an objective measure of a new product's value considers the benefit to patients, compared to a standard of care; the reduced need--and therefore costs--of other health care interventions; and any increase in quality of life and productivity. We believe our pricing reflects these factors. We also consider factors such as the affordability for patients and any unique factors specific to the medicine, like the need to support ongoing clinical trials, implement important regulatory commitments, or develop sophisticated patient support tools that improve care management and help decrease the total cost of care. Additionally, under our pricing principles, we limit annual list price increases to the National Health Expenditure, which is CMS's projected annual health-care spending growth rate. Since we established our pricing principles in 2017, all price increases for our insulin products have been at or below NHE. Sanofi offers rebates to health plans and PBMs in order to help secure and maintain favorable formulary positions. Our aim in these negotiations is to establish affordable access to patients. Currently, however, payers and PBMs inconsistently pass through to patients the growing savings they receive from increased negotiated rebates and discounts. Accordingly, despite increasing rebates and lower net prices, out-of-pocket costs for many patients have continued to grow. Sanofi supports policies that would pass through PBM rebate savings to patients at the pharmacy counter in the form of lower cost-sharing. Question. If CMS finalizes the rebate rule, do you anticipate future products entering the market with significantly lower initial list prices? Answer. We can only speak for Sanofi. If (1) the proposed changes to the anti-kickback statute safe harbors were codified, and (2) Congress implemented similar changes to the commercial insurance market, Sanofi would lower the list prices of its prescription medications for products in competitive categories for which there is currently a material difference between list price and net price on the assumption that patient access and affordability would be improved. Sanofi also supports policy changes that would de-link other payments in the pharmaceutical supply chain from list price. We support extending the intent behind the anti-kickback statute safe harbor proposed rule to the commercial market so that incentives are aligned across the marketplace. Together, we believe these changes would facilitate Sanofi's ability to lower our list prices. However, we recommend a step-wise approach, implementing changes to the commercial market after the safe harbor rule is implemented on January 1, 2020. Such an approach would provide an opportunity for stakeholders and the government to identify unintended consequences, and address them, prior to extending these policies to the commercial market. We want to ensure that the new system achieves its goal of improving affordability for patients. For instance, CMS should monitor and evaluate how the new system affects formulary access, utilization management, and patient cost-sharing, particularly with respect to medicines with a lower list price. We also have concerns that changes to the rebate system may lead to new fees, which would simply require manufacturers to pay previous rebate values in new ways, rather than creating savings for patients. Without a better understanding of how these policy changes ultimately would affect the competitive marketplace, patient access, and affordability, we are unable to quantify the amount of any potential list price reduction. When setting the price of a new medicine, Sanofi's decision making will continue to be guided by our pricing principles framework, which are discussed in Part 1 of this response. ______ Questions Submitted by Hon. Thomas R. Carper Question. What are your recommendations for lowering prices for the 40 percent of drugs that do not offer rebates in Medicare Part D? In the health insurance plans that you offer your employees, do you ask your insurers to pass through the full manufacturer rebates to the beneficiaries? Answer. To address prices of drugs that are not subject to rebates in Medicare Part D, Sanofi supports policies that would incentivize responsible pricing by tying smaller list price increases, or even list price reductions, to both access and affordability for patients. Sanofi also believes that value-based discounting arrangements could drive down the price of prescription drugs in all contexts, regardless of the existence of rebates, including for Medicare Part D. Sanofi favors reforms in applicable statutes and regulations to permit manufacturers and payers to adopt these arrangements more broadly than is the case today. The Sanofi medical plan is self-insured; as such, the company pays the majority (approximately 80 percent) of the health-care claims that are incurred by our employees and their dependents. Sanofi does not, therefore, pass rebates through to members. Importantly, the Sanofi PPO medical/Rx plan, which covers 90 percent of our employees who elect medical coverage, maintains very low member cost-sharing for prescriptions. For example, members incur no cost ($0 co-pays) for Sanofi and partner prescription drugs. For non-Sanofi prescriptions, the out-ofpocket expense varies for generic ($15/prescription), preferred brand ($25/prescription) and non- preferred brand ($40/prescription). Question. The systems for pricing and distributing drugs are opaque and difficult to understand. What are your recommendations for increasing transparency in how your companies set the list prices for drugs, and for improving transparency in the supply chain for prescription drugs? Would you support federal standards for transparency in setting the list prices for drugs? Answer. Sanofi supports increased system-wide transparency, which would improve competition by making relevant information available to patients and policymakers. Two years ago, Sanofi announced our progressive and industry-leading pricing principles to help stakeholders understand our pricing decisions and to advance a more informed discussion of issues related to the pricing of medicines.\25\ --------------------------------------------------------------------------- \25\ https://mediaroom.sanofi.com/en/articles/2017/sanofi-pricing- principles-for-the-u-s/. Sanofi's pricing policy includes a commitment to transparency in how we price new medicines coming to the market for the first time. When Sanofi sets the price of a new medicine, we hold ourselves to a transparent, rigorous, and structured process that includes consultation with external stakeholders. In our view, an objective measure of a new product's value considers the benefit to patients, compared to a standard of care; the reduced need--and therefore costs-- of other health care interventions; and any increase in quality of life and productivity. We believe our pricing reflects these factors. We also consider factors such as the affordability for patients and any unique factors specific to the medicine, like the need to support ongoing clinical trials, implement important regulatory commitments, or develop sophisticated patient support tools that improve care --------------------------------------------------------------------------- management and help decrease the total cost of care. Tied to our pledge to keep annual list price increases at or below the projected U.S. National Health Expenditure growth rate, Sanofi has committed to providing its rationale should Sanofi increase any list price above the NHE growth rate, highlighting clinical value, real world evidence, regulatory change, new data, or other circumstances that support our decision. Sanofi also has committed to disclose annually our aggregate U.S. gross and net price changes from the prior calendar year. These data may help illustrate how pricing changes accrue to manufacturers versus others in the value chain, highlighting our discrete role in the broader U.S. health care system. We support Federal standards for transparency in the rationale for price increases above a certain threshold, provided that there are appropriate guardrails. Sanofi believes that increased transparency should accomplish three goals: (1) Preempt similar state laws, as was done with the Sunshine Act, to create a consistent reporting process. (2) Ensure information that if released publically could be anti-competitive is kept confidential. (3) Take a holistic approach to transparency, such as requiring PBMs to disclose when the net price of a medicine has declined and whether the increased rebates are used to lower costs for patients or for other reasons. We would be willing to work with this Committee on appropriate policy solutions. Question. In nearly every sector of the health-care industry, Medicare, Medicaid, employers, and insurers are moving away from fee- for-service payments to reimbursements based on value and performance. Prescription drugs and medical devices were the glaring exceptions to this trend until recently. How many of your drugs are included in value-based contracts and how many patients are benefiting from them? How do these value-based contracts work to lower drug prices for both patients and taxpayers? Answer. At this time, Sanofi has entered into value-based arrangements involving three Sanofi products: Soliqua 100/33, Praluent, and Kevzara. At present, we are not able to identify the specific number of patients who benefit from these arrangements. Sanofi believes that encouraging an environment that is supportive of value-based arrangements would help promote drug affordability, increase patient access to medicines, and improve patient adherence and outcomes. Specifically, although there are different types of these agreements, value-based contracts generally tie prices and payments to the value of a particular prescription drug product--while potentially reducing patient out-of-pocket costs and providing patients with better access to the most innovative drug products. A manufacturer could, for example, condition payment for a product on its success in meeting a predefined clinical outcome, and this type of arrangement could make drugs more affordable and lower costs throughout the system. Question. Last year, Senator Portman and I did an investigation on the pricing of an opioid overdose reversal drug called EVZIO, manufactured by Kaleo. Kaleo increased the price of EVZIO from $575 in 2014 to $4,100 in 2017. We found that the best price Medicare was able to get for EVZIO, about $4,000, was much higher than the price other Federal programs and private insurers were able to get. It seemed that Kaleo was able to get this higher price of $4,000 from Medicare by helping doctors fill out paperwork showing that the drug was medically necessary, even though there are cheaper alternatives on the market. As a result of the investigation, Kaleo announced it will bring a generic version of the drug to market at only $168 per pack. Are any of your companies providing medical necessity paperwork to doctors in order to get your drugs covered by Medicare? Answer. No. Sanofi does not provide patient-specific clinical or medical necessity information to physicians in furtherance of the Medicare coverage of any of Sanofi's products for particular patients. Consistent with guidance from the Department of Health and Human Services Office of Inspector General (OIG), Sanofi typically provides physicians with a copy of an applicable blank prior authorization form, or in some cases, the form with only the physician's demographic information filled out, along with separate instructions for filling out the form. Also, in keeping with OIG guidance, Sanofi provides physicians with template appeals letter for instances in which a physician needs to appeal non-coverage for a Sanofi product. These template letters do not include any patient medical information, and instead are provided only as a guide for physicians to describe the reasons that the patient requires his or her prescribed Sanofi product.\26\ Similarly, Sanofi provides physicians with template letters of medical necessity, which do not offer medical information on specific patients. Instead, these documents provide a general framework pursuant to which physicians may prepare their own, patient-specific letters of medical necessity.\27\ These measures comply with the OIG guidance in that they provide ``limited support'' in connection with a purchase or prescribing decision for a Sanofi product. --------------------------------------------------------------------------- \26\ See, e.g., https://www.visitspconline.com/servlet/ servlet.FileDownload?file=00P3600000Q1T boEAF. \27\ See, e.g., https://www.visitspconline.com/servlet/ servlet.FileDownload?file=00P3600000Q1T byEAF. Question. In 2017, the Rand Corporation estimated that biosimilar drugs, which are competitors to complex, biologic drugs, could save the United States more than $50 billion over the next decade. Some of you have also argued that increasing the use of biosimilar drugs would help lower drugs costs for consumers and taxpayers. What is delaying the uptake of biosimilar drugs in the United States? What policies do you --------------------------------------------------------------------------- recommend to increase the development of biosimilar drugs? Answer. Sanofi supports the entry of biosimilar medicines in the market after a reasonable period of time after the innovator biologic is developed, which we believe is already reflected in U.S. law. There are changes already in place that will help patients and taxpayers realize the benefit of biosimilars. Specifically, in March 2020, certain biologics that are currently regulated as drugs, including long acting insulins, will be regulated as biologics and therefore will be subject to the existing biosimilars pathway. We expect the change in regulation to spur the continued development of substitutable or interchangeable products, and to increase competition in this space generally. Further, we believe that as health-care providers become more familiar with biosimilars, the uptake of biosimilar drugs will increase. Findings from a recent review show that there is an overall lack of biosimilar familiarity among U.S. and European health-care providers, leading to low prescribing comfort as well as safety and efficacy concerns.\28\ The study concludes that, to realize the full cost-saving potential of biosimilar medicines, clinician-directed biosimilar education is necessary to address the gaps in biosimilar knowledge, facilitate prescribing changes, and ultimately increase biosimilar use. --------------------------------------------------------------------------- \28\ See ``Factors Affecting Health Care Provider Knowledge and Acceptance of Biosimilar Medicines: A Systematic Review,'' 25 J. Managed Care & Specialty Pharm. 102-112 (Jan. 2019), available at https://www.jmcp.org/doi/10.18553/jmcp.2019.25.1.102. ______ Questions Submitted by Hon. Benjamin L. Cardin Question. The United States is one of the only countries in the world to allow prescription drug manufacturers to advertise directly to consumers through magazines, billboards, radio, and television commercials. While I will not argue that it is beneficial to educate consumers about an unfamiliar disease and encourage them to seek medical help, most commercials from all of your companies recommend asking about a specific brand name drug, not a medical condition. Furthermore, even if your advertisements follow all FDA rules and list medication side effects, they also almost always list these while a smiling, apparently healthy person is walking on a beach. Researchers say that this type of imagery, combined with viewing hours of drug commercials each month, leads consumers to underestimate the risks associated with medications. For the past decade, studies have shown that aggressive direct-toconsumer advertising is associated with rising drug prices and an increase in inappropriate drug prescriptions. Since researchers have concluded that consumers are misunderstanding the benefits and risks described in your ads, what further policies could help you and your colleagues ensure that you are educating patients in a clear manner? Answer. Sanofi believes DTC advertisements can play an important role in both raising awareness about a disease and educating patients about their treatment options. The benefits of DTC advertisements are reflected in the results of a recent survey conducted by Princeton Survey Research Associates International, which found that DTC advertisements often prompt conversations about alternatives such as generics or lifestyle changes, and prompt positive behaviors, such as information-seeking and medicine adherence.\29\ --------------------------------------------------------------------------- \29\ https://www.phrma.org/report/2017-direct-to-consumer- advertising-survey-results. When DTC advertisements solely discuss a particular disease or condition without mentioning or alluding to a specific drug, FDA considers the advertisements disease awareness communications. Disease awareness communications are not considered promotional labeling or advertising, and thus such communications are not subject to the requirements of the Federal, Food, Drug and Cosmetic Act (FDCA) or FDA regulations. In contrast, DTC advertisements that make claims about a drug are subject to requirements governing disclosure of risk and other information, including a statutory requirement to include a brief summary relating to side effects, contraindications, and effectiveness. FDA's prescription drug advertising regulations distinguish between print and broadcast advertisements, which require a ``brief summary'' for print advertisements and what is referred to as a ``major statement'' of risks for broadcast advertisements. FDA regulations also set forth additional requirements for information to be included in both print and broadcast advertisements. Certain broadcast advertisements, including the initial television advertisement for a prescription drug and all television advertisements for prescription drugs subject to a Risk Evaluation Mitigation Strategy with elements to assure safe use, are subject to pre-dissemination review by FDA. Even where a television advertisement is not subject to mandatory review, sponsors may elect to voluntarily submit the advertisement to FDA for --------------------------------------------------------------------------- advisory review. While the time-limited nature of broadcast DTC advertisements can present challenges in ensuring a drug advertisement presents all information required by the FDCA and FDA regulations in a manner easily digestible to a consumer, or even HCP, audience, Sanofi strives to disseminate balanced DTC advertisements that clearly and effectively communicate a product's benefits and risks. To that end, prior to airing any DTC television advertisement, Sanofi submits each advertisement to FDA for pre-dissemination review and incorporates FDA's comments, even when such review is not required for the advertisement in question. To further the objective of ensuring that DTC advertisements educate consumers about potential treatment options in a non-misleading manner, we believe industry would benefit from a regulatory framework that allows for greater flexibility in the risk and other information required to be included in broadcast advertisements, including, for example, the flexibility to focus on select significant risks in the advertisement itself while directing consumers to a website for a more fulsome discussion of a product's risks. FDA has acknowledged that its regulations provide ``only limited flexibility'' for risk disclosure in broadcast advertisements. Thus, allowing for greater flexibility in content control in DTC advertisements would likely require amending existing FDA regulations, as well as potentially the underlying statutory provisions governing the information required to be disclosed in advertisements. pharmaceutical companies continue to raise prices Question. As you are well aware, high prescription drug prices are the number one concern for Americans and their families. According to the Organization for Economic Cooperation and Development, the average American spends around $1,208 annually on prescription drugs. There have been several instances where brand name or even generic drugs that have been on the market for years continue to increase in price. One of the most well-known examples is Mylan's increase of the price of EpiPen from less than $100 in 2007 to more than $600 in 2016. Another example, is the ever-increasing price of insulin. Sanofi increased the price of a vial of Lantus from $88.20 in 2007 to $307.20 in 2017. And those are just a small sample of price increases. Why don't we see price decreases for drugs that have been on the market for years without new formulations or added benefit? Answer. Current regulations, including price reporting requirements, create uncertainty about the implications of lowering a list price. We are working with CMS on alternatives that could enable us to put lower list price versions of our products on the market. Until such system changes are implemented, we are working to improve the affordability of our products for those who are uninsured or underinsured through our many patient support programs. It is important to note, as well, that revenues from existing therapies are used to fund future R&D across therapeutic areas. Sanofi's R&D strategy is to allocate resources to priority therapeutic areas based both on scientific opportunity and unmet medical need, leveraging multiple therapeutic modalities and accelerating early development. Our R&D pipeline currently contains 81 projects, including 33 new molecular entities in clinical development, and 35 projects are in Phase III or have been submitted to regulatory authorities. From 2008 to 2017, Sanofi invested over $55 billion dollars globally in R&D. Last year we invested almost $7 billion globally, or approximately 24% of our gross profits, in our research and development activities. We expect to continue to spend around the same on R&D in the coming years. pay for delay Question. Pay for delay is a tactic that more and more branded drug manufacturers have been using to stifle competition from lower-cost generic manufacturers. This allows you to sidestep competition by offering patent settlements that pay generic companies not to bring lower-cost alternatives to market. These ``pay-for-delay'' patent settlements benefit both brand-name pharmaceutical companies by helping them avoid costly patent litigation and general manufacturers by rewarding them a hefty sum to delay entering the market with a cheaper drug alternative. However, these deals do not benefit consumers. According to an FTC study, these anticompetitive deals cost consumers and taxpayers $3.5 billion in higher drug costs every year. Does your company partake in pay-for-delay settlements? Answer. No, Sanofi does not enter into ``pay for delay'' agreements that prohibit generic drug or biosimilar development after the expiration of a patent. Sanofi has reached settlements in patent infringement cases, and these agreements have allowed the generic company to commercialize its product before the expiration of the applicable patent covering Sanofi's innovator product. Question. Why would a pharmaceutical company enter into a pay-for delay agreement? Answer. We can only speak for Sanofi, and we do not enter into ``pay-for-delay'' settlement agreements. Question. Do you think these agreements stifle competition and prevent generic alternatives to your branded medications? Answer. With respect to patent litigation, generally, Sanofi believes it is inappropriate to presume that any settlement of patent litigations related to pharmaceutical products is anticompetitive. Such settlements are often the most efficient and effective way to resolve disputes regarding patented drugs. Additionally, they often lead to the earliest appropriate entry of generic products into the market thereby benefiting patients--earlier than expiration of the relevant patents. Each patent litigation and potential settlement presents unique factors and must be considered individually and in light of the relevant circumstances. drug rebate rule Question. In January, the Department of Health and Human Services' (HHS) Office of Inspector General (OIG) promulgated a new regulation to remove regulatory safe harbor protections under the Anti-Kickback Statute (AKS) for rebates on prescription drugs rebates paid by manufactures to PBMs under Medicare Part D and for Medicaid managed care organizations (MCOs). The OIG proposal attempts to ban most rebates by eliminating their regulatory protections. The rule is predicted to increase net drug costs in its early years. The CMS actuaries estimate it would cost $196 billion over 10 years. Despite this high price tag, the beneficiary benefits are limited. The proposed rule notes that under the CMS Actuary's analysis, the majority of beneficiaries would see an increase in their total out- of-pocket payments and premium costs; reductions in total cost sharing will exceed total premium increases. I wanted to ask a question about the administration's rebate rule, which I understand that many of the drug manufacturers, and your main trade association, strongly support. According to an analysis of the rule by the Office of Actuaries at CMS, drug manufacturers are likely to initially retain 15 percent of the current rebates as higher net drug prices. Given that estimate, can you provide the committee with any assurances that prices will not increase under this proposed rule? Answer. At this time, it is difficult to predict the effect of the administration's proposed rule. It is our expectation that it will result in lower out-of-pocket costs for patients by protecting only manufacturer rebates to Medicare Part D and Medicaid MCO plans and their PBMs that are reflected in the point-of-sale price. Without a better understanding of how these policy changes ultimately would affect the competitive marketplace, patient access, and affordability, however, we are unable to provide assurances regarding how prices might change. We want to ensure that the new system achieves its goal of improving affordability for patients. For instance, CMS should monitor and evaluate how the new system affects formulary access, utilization management, and patient cost-sharing, particularly with respect to medicines with a lower list price. We also have concerns that changes to the rebate system may lead to new fees, which simply require manufacturers to pay previous rebate values in new ways, rather than creating savings for patients. ______ Questions Submitted by Hon. Sherrod Brown Question. According to an article recently published in the Journal of the American Medical Association, medical marketers spent nearly $30 billion dollars in 2016, up from $17 billion in 1997. Direct-to- Consumer (DTC) advertising had the biggest percentage increase: from $2.1 billion, or 11.9% of all medical marketing, in 1997 to $9.6 billion, or 32% of total spending, in 2016. Can each of you please provide what your ratio of spending on sales and marketing to research and development is today? Answer. In 2018, Sanofi's global ratio of spending on sales and marketing \30\ to research and development was approximately 117 percent. --------------------------------------------------------------------------- \30\ ``Sales and marketing'' includes, but is not limited to: sales force, promotion, and marketing management. --------------------------------------------------------------------------- price-gouging Question. Sanofi, as I understand it, has made a pledge to the public to limit its price increases to the national health expenditures growth projection. As the chair of the board of directors at PhRMA would you support membership requirements that would cap annual price increases for drugs sold as part of Medicare, similar to what Sanofi has pledged? Given that PhRMA members are considering creating higher standards for themselves, would you support an industry-wide standard on annual price increases that applies to all pharmaceutical corporations, whether or not they are members of PhRMA? Answer. Dr. Brandicourt appeared before the committee on behalf of Sanofi; we cannot speak on behalf of PhRMA or any other company. We note that pricing discussions among PhRMA members, or pharmaceutical manufacturers more generally, could implicate federal antitrust laws and therefore would be inappropriate. Two years ago, Sanofi announced our progressive and industry- leading pricing principles, which include a pledge to keep annual list price increases at or below the projected U.S. National Health Expenditure (NHE) growth rate, as calculated by CMS. In 2018, all of Sanofi's price increases across its medicines were consistent with those pricing principles, as are all pricing actions taken in 2019. Question. What policies would you propose to help ensure lower launch prices for new drugs? Answer. For Sanofi, the key requirement for any policy solution is that it should result in improved access and lower prescription out-of- pocket drug costs for patients, while maintaining incentives for innovations. To reform the current misaligned incentives in the current system, Sanofi supports de-linking payments to PBMs, payers and others in the supply chain from the list price. Additionally, we support policies that would incentivize lower launch prices, smaller list price increases, or even list price reductions, by requiring health plans to cover those medicines at an affordable co-pay level and only allow access restrictions consistent with the label and accepted best clinical practice. transparency Question. In many of your testimonies, you mentioned that the current system of pharmacy benefit manager (PBM) back-end rebates do not rarely results in a scenario where the PBM passes on savings to consumers at the point of sale (POS). The Administration recently proposed a rule to eliminate the anti-kickback statute safe harbor protections for these drug rebates. Do you agree that greater transparency should be required to understand how manufacturers and PBMs are negotiating prices and rebates to ensure that savings are passed down to beneficiaries? Answer. Yes. Sanofi supports policies, such as those proposed in the C-THRU Act, that would encourage or require PBMs and payers to be transparent regarding how they use manufacturer rebates and pass through manufacturer rebates to patient at point of sale in the form of lower out-of-pocket costs. As part of our pricing principles, Sanofi voluntarily discloses annually our aggregate U.S. gross and net price changes from the prior calendar year. These data help illustrate how pricing changes accrue to manufacturers versus others in the value chain, highlighting our discrete role in the broader U.S. health care system. pbms Question. An Axios article from March 7, 2019 highlights the fact that, while ``pharmaceutical companies put a lot of the blame for high drug prices on pharmacy benefit managers,'' many large pharmaceutical companies ``rely on PBMs to manage their own health-care benefits.'' In your role as an employer, does your company contract with a pharmaceutical benefit manager (PBM) to administer the prescription drug benefits for your employees and negotiate lower drug costs on your behalf? Answer. Yes, we do. Question. For those of you who do use a PBM to help manage the prescription drug benefit for your employees, how do you utilize the rebates your PBM negotiates to lower health-care costs or drug costs for your employee plans and what does your company do with that savings? Specifically, do the savings go toward lowing premiums? Answer. The Sanofi medical plan is self-insured; as such, the company pays the majority (approximately 80 percent) of the health-care claims that are incurred by our employees and their dependents. Therefore, Sanofi uses rebates to defray the overall cost of its health plan, which allows us to keep plan costs stable for all participants. We offer our employees generous healthcare coverage and have been able to keep the deductibles of our PPO, which covers 90% of our employees who elect medical coverage, at $200 for single coverage and $400 for family coverage over the past few years. With respect to our PPO prescription drug benefit, members incur no cost ($0 co-pays) for Sanofi and partner prescription drugs. For non-Sanofi prescriptions, the out-of-pocket expense varies for generic ($15/prescription), preferred brand ($25/prescription) and non-preferred brand ($40/ prescription). The Sanofi plan's actuarial value is around 90%, which puts it at the ``platinum'' level. Question. For those of you who do use a PBM to help manage the prescription drug benefit for your employees, does your PBM offer point-of-sale rebates to your employees? Answer. Yes, our PBM does offer point-of-sale rebates, however only around 8 percent of its clients currently are enrolled in point-of-sale rebates. ______ Questions Submitted by Hon. Sheldon Whitehouse Question. Please describe any policy changes you support that would result in your company lowering the list prices of its drugs. Answer. For Sanofi, the key requirement for any policy solution is that it should result in improved access and lower prescription out-of- pocket drug costs for patients, while maintaining incentives for innovations. To reform the current misaligned incentives in the current system, Sanofi supports de-linking payments to PBMs, payers and others in the supply chain from the list price. Additionally, we support policies that would incentivize lower launch prices, smaller list price increases, or even list price reductions, by requiring health plans to cover those medicines at an affordable co-pay level and only allow access restrictions consistent with the label and accepted best clinical practice. Sanofi also supports the intent behind legislation like the SPIKE Act, which would impose price transparency requirements on companies that increase the list price of a particular drug over a certain threshold. We believe that increased transparency should accomplish three goals: (1) preempt similar state laws, as was done with the Sunshine Act, to create a consistent reporting process; (2) ensure information that if released publically could be anti-competitive is kept confidential; and (3) take a holistic approach to transparency, such as requiring PBMs to disclose when the net price of a medicine has declined and whether the increased rebates are used to lower costs for patients or for other reasons. Question. How much does your company's research and development portfolio rely on taxpayer-funded research conducted by the National Institutes of Health (NIH)? How many of your company's products are based, at least in part, on NIH research, and how many are the result of research funded solely by your company? Answer. In identifying targets for new drugs, Sanofi relies on global science, which often includes NIH-funded research. Sanofi has collaborated with NIH on various research and development (R&D) initiatives on projects related to HIV, Epstein-Barr virus, influenza, and respiratory syncytial virus. While there is no question that NIH plays a vital role in basic research and early discovery, the majority of Sanofi's current portfolio of products in the pre-development to development phases do not rely on NIH funding. Sanofi reinvests a significant portion of its revenue into the R&D of new or improved medicines and vaccines. Last year, Sanofi globally spent almost $7 billion on R&D globally, an increase of approximately 7 percent from 2017, which reflects our commitment to bringing better therapies to patients. Sanofi plans to maintain this level of R&D investment through 2021, and our R&D pipeline now contains 81 projects, including 33 new molecular entities in clinical development, and 35 projects that are in Phase III or have been submitted to regulatory authorities. This investment means that Sanofi potentially will seek approval for nine new medications in the next three years, primarily in therapeutic areas where Sanofi sees the greatest nexus between our expertise and patient need: diabetes, vaccines, oncology, immunology, rare diseases, and rare blood disorders. Question. In each of the last 5 years, how much has your company spent on research and development versus the advertising and marketing of your products? Answer. ------------------------------------------------------------------------ Research and Advertising and USD \31\ Development Marketing \32\ ------------------------------------------------------------------------ 2018 $6,954,920,000 $4,519,400,000 ------------------------------------------------------------------------ 2017 $6,238,080,000 $3,764,280,000 ------------------------------------------------------------------------ 2016 $5,689,200,000 $3,006,300,000 ------------------------------------------------------------------------ 2015 $5,590,200,000 $2,773,100,000 ------------------------------------------------------------------------ 2014 $6,160,440,000 $2,673,000,000 ------------------------------------------------------------------------ \31\ Sanofi reports its financials in Euros. All financial figures reported in this document have been converted from Euros into U.S. dollars. These are Sanofi global financial figures. \32\ Includes global spending on ``promotion'' and ``marketing management.'' Question. During the hearing, you mentioned that your company would be likely to lower the list prices of its drugs if the recent proposal by the Trump administration to change the current system of rebates was extended to the private market. If the policy was extended to the private market, how large would the list price reductions be relative to the size of the rebates your company is currently providing? Answer. If (1) the proposed changes to the anti-kickback statute safe harbors were codified, and (2) Congress implemented similar changes to the commercial insurance market, Sanofi would lower the list prices of its prescription medications for products in competitive categories for which there is currently a material difference between list price and net price on the assumption that patient access and affordability would be improved. Sanofi also supports policy changes that would de-link other payments in the pharmaceutical supply chain from list price. We support extending the intent behind the anti-kickback statute safe harbor proposed rule to the commercial market so that incentives are aligned across the marketplace. Together, we believe these changes would facilitate Sanofi's ability to lower its list prices. However, we recommend a step-wise approach, implementing changes to the commercial market after the safe harbor rule is implemented on January 1, 2020. Such an approach would provide an opportunity for stakeholders and the government to identify unintended consequences, and address them, prior to extending these policies to the commercial market. We want to ensure that the new system achieves its goal of improving affordability for patients. For instance, CMS should monitor and evaluate how the new system affects formulary access, utilization management, and patient cost-sharing, particularly with respect to medicines with a lower list price. We also have concerns that changes to the rebate system may lead to new fees, which simply require manufacturers to pay previous rebate values in new ways, rather than creating savings for patients. Without a better understanding of how these policy changes ultimately would affect the competitive marketplace, patient access, and affordability, we are unable to quantify the amount of any potential list price reduction. Question. How will this proposal affect how your company sets the list prices for new drug products? Answer. When setting the price of a new medicine, Sanofi's decision making will continue to be guided by our pricing principles framework. When Sanofi sets the price of a new medicine in the U.S., we hold ourselves to a rigorous and structured process that includes consultation with external stakeholders. In our view, an objective measure of a new product's value considers the benefit to patients, compared to a standard of care; the reduced need--and therefore costs-- of other health-care interventions; and any increase in quality of life and productivity. We believe our pricing reflects these factors. We also consider factors such as the affordability for patients and any unique factors specific to the medicine, like the need to support ongoing clinical trials, implement important regulatory commitments, or develop sophisticated patient support tools that improve care management and help decrease the total cost of care. To the extent reform of the anti-kickback statute safe harbors results in changes in the competitive marketplace, patient access, and affordability, the rule is likely to affect our pricing of new medicines. Question. If the proposal is finalized and not extended to the private market, will your company make any list price reductions? If so, how large would the reductions be relative to the size of the rebates your company is currently providing? Answer. Sanofi is committed to working with other stakeholders to lower patient out-of-pocket costs, and the company will carefully review any final rule issued by HHS regarding the Anti-Kickback Statute and its safe harbor regulations--with the goal of providing point-of- sale discounts to patients, in accordance with law, to lower their out- of-pocket costs. Without addressing the currently misaligned incentives across all payer channels, it is unclear the extent to which Sanofi would be able to lower list prices. We would need a better understanding of how the rule ultimately would affect the competitive marketplace, patient access, and affordability in both the government and commercial insurance markets in order to quantify the amount of any potential list price reduction. ______ Question Submitted by Hon. Maggie Hassan Question. In June of 2018, the Medicaid and CHIP Payment and Access Commission (MACPAC) unanimously recommended under Recommendation 1.1 in their annual report to Congress that Congress remove the statutory requirement that manufacturers blend the average manufacturer price (AMP) of a brand drug and its authorized generic.\33\ --------------------------------------------------------------------------- \33\ MACPAC, ``Improving Operations of the Medicaid Drug Rebate Program,'' https://www.macpac.gov/wp-content/uploads/2018/06/Improving- Operations-of-the-Medicaid-Drug-Rebate-Program.pdf. This requirement created an unintended loophole. Rather than use the price of the authorized generic, drug companies can sell its authorized generic to a corporate subsidiary at an artificially lower price, and use that lower price to bring down the AMP, which in turn --------------------------------------------------------------------------- lowers the rebate obligation. Does your company engage in this practice? Has your company ever engaged in this practice in the past? Answer. Sanofi currently markets authorized generic versions of certain of its products, through corporate affiliates, under separate National Drug Codes (``NDC''). Sanofi's general approach for these products has been that if two products share the same drug, dosage form, and strength, and both are sold by the same corporate entity or Sanofi business unit, then their sales are blended for the calculation of AMP and Best Price. ______ Questions Submitted by Hon. Catherine Cortez Masto Question. In October you were asked by a reporter whether you would lower the price of insulin if point-of-sale rebates were enacted. Your response was, ``We realize that some medicines remain economically out of reach for some patients. We take this issue seriously and will continue to seek innovative solutions to help make insulins more affordable for patients.'' Please answer that question more specifically: will you lower your list price in response to the rebate rule? Answer. If (1) the proposed changes to the anti-kickback statute safe harbors were codified, and (2) Congress implemented similar changes to the commercial insurance market, Sanofi would lower the list prices of its prescription medications for products in competitive categories for which there is currently a material difference between list price and net price on the assumption that patient access and affordability would be improved. Sanofi also supports policy changes that would de-link other payments in the pharmaceutical supply chain from list price. We support extending the intent behind the anti-kickback statute safe harbor proposed rule to the commercial market so that incentives are aligned across the marketplace. Together, we believe these changes would facilitate Sanofi's ability to lower its list prices. However, we recommend a step-wise approach, implementing changes to the commercial market after the safe harbor rule is implemented on January 1, 2020. Such an approach would provide an opportunity for stakeholders and the government to identify unintended consequences, and address them, prior to extending these policies to the commercial market. We want to ensure that the new system achieves its goal of improving affordability for patients. For instance, CMS should monitor and evaluate how the new system affects formulary access, utilization management, and patient cost-sharing, particularly with respect to medicines with a lower list price. We also have concerns that changes to the rebate system may lead to new fees, which simply require manufacturers to pay previous rebate values in new ways, rather than creating savings for patients. Without a better understanding of how these policy changes ultimately would affect the competitive marketplace, patient access, and affordability, we are unable to quantify the amount of any potential list price reduction. Question. As a portion of your revenue, for what percentage of the drugs in your portfolio do you offer no rebates? Based on the drugs in your pipeline, do you foresee that portion growing? For those drugs is your list price equal to your net price? Answer. When considering rebates paid by Sanofi in any form, including those that are government-mandated, Sanofi offers rebates on all of its products at some point in the distribution channel. We do not expect that this will change based on the company's pipeline. Question. Do you invest more in R&D than you generate in U.S. sales revenue? Please include specific figures. Answer. In 2018, Sanofi spent $6,954,920,000 globally on R&D, a 7- percent increase over 2017 and approximately 24 percent of its global gross profits. In 2018, Sanofi's U.S. net sales were $13,617,200,000. Answer. Do you invest more in R&D than you spend on marketing and administration? What company functions do you consider to be included in administration? Please include specific figures. Answer. Yes. In 2018, Sanofi spent $6,954,920,000 globally on R&D, and $6,921, 880,000 globally on marketing and administration. ``Administration'' includes, but is not limited to: finance, human resources, external affairs, legal, business services, business development, and internal audit. Question. Do you invest more in R&D than you spend on marketing and sales? What company functions do you consider to be included in sales? Please include specific figures. Answer. In 2018, Sanofi spent $6,954,920,000 globally on R&D, and $8,154,980,000 globally on marketing and sales. The primary function included in ``sales'' is the sales force. Question. Why do you advertise for the drugs you manufacture? What factors do you consider in choosing which drugs you advertise? Answer. Sanofi believes that advertising is an important tool to inform and educate the public about its medicines, while raising general awareness of diseases that are frequently surrounded by stigma. We are committed to ensuring that our advertisements provide accurate, accessible, and useful health information to patients and consumers. Our communications are designed to educate patients and consumers about serious health conditions and the availability of treatments, and to encourage them to seek guidance from their healthcare professionals about appropriate treatment. We consider a variety of factors in determining whether and how to advertise a product, including patient needs and the unique aspects of an individual product or disease state. ______ Independent Medical Education Grants 1st Jan 2015-30th June 2015 Sanofi US and its affiliate Genzyme Corporation are committed to supporting independent medical education activities in therapeutic areas in which the Company is involved, for healthcare professionals, patients, and consumers to improve patient care and health outcomes in therapeutic areas in which the Company is engaged. Sanofi US and Genzyme Corporation are part of the Sanofi Group, a global pharmaceutical company. ---------------------------------------------------------------------------------------------------------------- Funding Amount Recipient Name(s) \1\ Activity Title \2\ ---------------------------------------------------------------------------------------------------------------- Academic CME, LLC Postgraduate Incorporating Advancements in Monoclonal Antibody $298,600.04 Institute for Medicine Therapeutics into Patient Management Strategies Collaboration \3\ within Dyslipidemia Academy of Managed Care Pharmacy The unmet needs of multiple sclerosis, and the $6,500 principles and current evidence in the use of DMTs Admin of the Tulane Educational Fund 7th Annual Tulane Symposium on Thyroid And Parathyroid $10,000.00 on behalf of TUHSC CCE Diseases Collaboration \3\ AKH Inc. Advancing Knowledge and American Society for Preventive Cardiology: Annual $10,000.00 Healthcare Cardiovascular Disease Prevention Conference American Academy of Physician AAPA Conference 2015--Neurology Track $5,000.00 Assistants American Academy of Physician AAPA Conference 2015--Endocrinology Track $5,000.00 Assistants American Academy of Physician AAPA Conference 2015--Nephrology Track $3,500.00 Assistants American Association of Clinical Georgia-AACE 2015 Annual Meeting $7,500.00 Endocrinologists American Association of Clinical Lipids Sessions at Endocrine University: Disease $5,000.00 Endocrinologists Management and Technology Skills for Endocrinology Fellows In Training American Association of Clinical Southern States--AACE 2015 Annual Meeting $7,500.00 Endocrinologists American Association of Clinical Diabetes Sessions At Endocrine University: Disease $25,000.00 Endocrinologists Management and Technology for Endocrinology Fellows in Training American Association of Clinical AACE 24th Annual Scientific & Clinical Congress $47,350.00 Endocrinologists (Thyroid Sessions) American Association of Clinical AACE 24th Annual Scientific & Clinical Congress $47,350.00 Endocrinologists (Diabetes Session) American Association of Clinical Diabetes Sessions at AACE 24th Annual Scientific And $47,350.00 Endocrinologists Clinical Congress American Association of Clinical Mid Atlantic Chapter of The American Association of $7,500.00 Endocrinologists Clinical Endocrinologists 13th Annual Meeting & Symposium American Association of Clinical Mid Atlantic Chapter of the American Association of $7,500.00 Endocrinologists Clinical Endocrinologists 13th Annual Meeting 7 Symposium American Association of Clinical California Chapter of The American Association of $20,000.00 Endocrinologists Clinical Endocrinologists Presents: Hot Topics in Diabetes and Endocrinology for Primary Care American Association of Clinical LDL-C Reduction in the High-Risk Patient: How Low $261,057.00 Endocrinologists Medtelligence, LLC Should We Go? 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Postgraduate Institute for Medicine Differentiating Therapeutic Approaches for Relapsing $50,000.00 Enquiring Minds LLC Multiple Sclerosis Primary Care Education Consortium Managing Postprandial Hyperglycemia in Type 2 $230,465.30 Diabetes: Combining Basal Insulin and Glucagon-Like Peptide-1 Receptor Agonists Primary Care Education Consortium Strategies for Intensifying Insulin Management in Type $275,955.15 2 Diabetes PRIME Education Inc. (PRIME) Shifting Paradigms in Lipid Management $215,850.00 Collaboration \3\ PRIME Education Inc. (PRIME) New Therapies and Evidence for Patient-Centered $205,000.00 Hypercholesterolemia Care--Evolving Roles for Collaboration \3\ Pharmacists PRIME Education Inc. (PRIME) Evidence-Based Decisions and a Mock P&T: The Role of $161,020.00 New LDL-C Reduction Therapy Pri-Med Institute, LLC (d/b/a pmiCME) Optimizing Insulin Therapy for Patients with Type 2 $805,275.00 Diabetes: Existing Challenges and New Opportunities for Improved Care Pri-Med Institute, LLC (d/b/a pmiCME) Evolving Insulin Therapy: Optimizing Care Through $812,950.00 Horizon CME, Inc. Proper Selection & Use Pri-Med Institute, LLC (d/b/a pmiCME) Combining GLP-1 Receptor Agonists With Basal Insulin: $797,090.00 Horizon CME, Inc. Realizing the Potential in Type 2 Diabetes ProCE, Inc. Safe Use of Concentrated Insulin: Helping Patients to $87,575.00 Get It Right Purdue University Medikinetics LLC Addressing Postprandial Glucose Excursions in Type 2 $363,648.00 Diabetes with Inhaled Insulin Purdue University PeerView Institute Peerview Video Inexchange, ``Contemporary Multiple $38,000.00 for Medical Education, Inc. 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The Ohio State University, Endocrine Update 2015 $10,000.00 The University of Texas MD Anderson 6th Current Concepts in the Management of Thyroid & $20,000.00 Cancer Center Parathyroid Neoplasms The University of Texas Southwestern 37th Annual Carrell-Krusen Neuromuscular Symposium $20,000.00 Medical Center at Dallas The University of Texas Southwestern Neuromuscular Medicine Fellowship $74,100.00 Medical Center at Dallas The University of Toledo Outcomes of Myeloma: The Optimizing Sequenxe of $3,000.00 Treatments Including Transplant Trustees of Columbia University in Renal Biopsy in Medical Diseases of the Kidneys $3,500.00 the City of New York UC Regents Diabetes Update and Advances In Endocrinology And $7,500.00 Metabolism UC Regents LSD Genetic Counseling Fellowship $75,000.00 Ultimate Medical Academy, LLC dba Cutting Edge Of Transplantation 2015 $30,000.00 Global Education Group American Society of Transplantation University of California Irvine Genetic Neuromuscular Diseases Fellowship $75,000.00 University of California, San Diego 34th Annual Advanced Nephrology: Nephrology for the $10,000.00 Consultant University of California, San Diego 20th International Conference on Advances in Critical $5,000.00 CRRT Inc. Care Nephrology--AKI & CRRT 2015 University of Cincinnati CORE Medical Navigating the Evolving Therapeutic Landscape in $65,500.00 Education, LLC. Advanced Prostate Cancer University of Cincinnati Paradigm Multidisciplinary Approach to Charting a Treatment $94,650.00 Medical Communications, LLC Course for Men with Metastatic Castration-Resistant Prostate Cancer University of Cincinnati Paradigm Advancing Treatment Strategies in Metastatic $95,000.00 Medical Communications, LLC Castration-Resistant Prostate Cancer: The Urologist's Role University of Florida Pediatric Neuromuscular Fellowship $75,000.00 University of Florida Foundation Southern Salt, Water, and Kidney Club 56th Annual $5,000.00 Scientific Meeting University of Kansas Endowment Neuromuscular Review Course Series 2015 $60,000.00 Association University of Massachusetts Medical MS Practice Update: Managing Walking Impairment, $30,000.00 School Neurogenic Bladder, Bowel and Sexual Dysfunction in Multiple Sclerosis University of Massachusetts Medical Understanding and Applying New Advances in Basal $303,080.00 School C-MEducation Resources, LLC Insulin Therapy University of Massachusetts Medical The IQ&A Interactive Diabetes Intelligence Zone: Focus $152,000.00 School C-MEducation Resources, LLC on Inhaled Insulin, Combination Regimens, and Postprandial Hyperglycemia University of Massachusetts Medical Novel Mechanisms and Advancing Therapeutic Paradigms $336,000.00 School C-MEducation Resources, LLC for Optimizing LDL--Focused Management and Collaboration \3\ Cardioprotection in the Diabetic Patient University of Massachusetts Medical New Frontiers and Treatment Advances for Atopic $366,000.00 School C-MEducation Resources, LLC Dermatitis: Focus on the Role of Established and Collaboration \3\ Evolving Biologic Therapies for Patients with Moderate-to-Severe and Treatment-Resistant Atopic Dermatitis University of Massachusetts Medical New Frontiers and Treatment Advances in Rheumatoid $345,000.00 School C-MEducation Resources, LLC Arthritis: Focus on Mechanisms of Action, Cytokine- Collaboration \3\ Mediated Inflammation and the Evidence for Safe and Effective Therapy for RA Through Inhibition of the IL- 6 Cytokine and Other Signaling Systems University of Massachusetts Medical Novel Mechanisms and Advancing Therapeutic Paradigms $465,900.00 School C-MEducation Resources, LLC for Optimizing LDL-Focused Management of Primary and Collaboration \3\ Familial Hypercholesterolemia University of Massachusetts Medical Understanding and Applying New Advances in Basal $971,000.00 School C-M Education Resources, LLC Insulin Therapy University of Massachusetts Medical New Frontiers and Emerging Treatment Paradigms for $347,000.00 School C-MEducation Resources, LLC Optimizing LDL-Targeted Cardiovascular Risk Reduction Collaboration \3\ University of Miami Pediatric Nephrology Seminar XLII and Renal Pathology $10,000.00 Course University of Pittsburgh Seventh Annual Multidisciplinary Thyroid Cancer $3,250.00 Symposium: Integrating the New ATA Guidelines into Clinical Practice University of Rochester, School of 2015 Society for Investigative Dermatology Annual $10,000.00 Medicine and Dentistry Society of Meeting Collaboration \3\ Investigative Dermatology University of Southern California 37th Thyroid Symposium 2015: Practical Solutions To $10,000.00 Complex Clinical Problems University of the Pacific Horizon Basal Insulin Therapy in the Treatment of Insulin $223,275.00 CME, Inc. Resistant Type 2 Diabetes: The Role of the Pharmacist in Ensuring Their Safe and Effective Use University of Virginia The 39th Annual Fitz-Hugh Symposium: Contemporary $10,000.00 Management and Cutting Edge Advances in Otolaryngology--Head & Neck Surgery (Special Emphasis on Laryngology and Head & Neck Endocrine Surgery) USF Health Professions Conferencing 12th Annual Rocky Mountain Metabolic Syndrome $5,000.00 Corporation CEConsultants, LLC Symposium VHA Inc. Treating Elevated LDL-C: Beyond Statins $85,000.00 Collaboration \3\ Wellmont Health System 13th Annual Diabetes Symposium $4,000.00 Yale University Diabetes 2015 $50,000.00 Yale University 2015 New England Thyroid Club Program $10,000.00 ---------------------------------------------------------------------------------------------------------------- \1\ Applicant names are provided by the requestor. If applicants apply as a group for a single educational activity; all applicants may be not be identified above. The Company funds other educational activities (including fellowships and non-physician and patient education); all of which do not appear on this report, but appear on other reports on this site. \2\ ``Funding Amount'' is the amount that the Company funded during Q3, 2015 identified above based upon an agreement. Recipients are required to return any unused funds. Information on unused funds returned by the applicant on activities are not reported. ``Funding Amount'' does not include funds that may have been provided by other affiliated Sanofi Company Entities (e.g., Sanofi Pasteur). \3\ Collaboration (Shared) Funding--is the full amount of a grant funded under an agreement with Regeneron, some or all of which may be shared between the collaborating entities. Independent Medical Education Grants 1st Jul 2015-30th Sep 2015 Sanofi US and its affiliate Genzyme Corporation are committed to supporting independent medical education activities in therapeutic areas in which the Company is involved, for healthcare professionals, patients, and consumers to improve patient care and health outcomes in therapeutic areas in which the Company is engaged. Sanofi US and Genzyme Corporation are part of the Sanofi Group, a global pharmaceutical company. ---------------------------------------------------------------------------------------------------------------- Funding Amount Recipient Name(s) \1\ Activity Title ($) \2\ ---------------------------------------------------------------------------------------------------------------- Academic CME, LLC APPLYING ADVANCED TREATMENT STRATEGIES WITHIN 326,430 RHEUMATOID ARTHRITIS Collaboration \3\ AKH Inc. Advancing Knowledge and FLORIDA SOCIETY OF RHEUMATOLOGY 2015 ANNUAL CME 5,000 Healthcare Florida Society of CONFERENCE Rheumatology American Academy of Continuing TRANSLATING CLINICAL DATA INTO NEPHROLOGY PRACTICE IN 149,800 Medical Education, Inc. THE MANAGEMENT OF HYPERPHOSPHATEMIA American Association of Clinical HEARTLAND-AACE 6TH ANNUAL MEETING 7,500 Endocrinologists American Association of Clinical ILLINOIS CHAPTER OF THE AMERICAN ASSOCIATION OF 5,000 Endocrinologists CLINICAL ENDOCRINOLOGISTS 5TH ANNUAL METING American Association of Diabetes INHALED INSULIN A BREATH OF FRESH AIR FOR THE 62,800 Educators Horizon CME, Inc. TREATMENT OF DIABETES American Diabetes Association 30TH ANNUAL CLINICAL CONFERENCE ON DIABETES: BEYOND 25,000 THE NUMBERS American Diabetes Association DIABETES AND ENDOCRINE DISORDERS FOR THE GENERALIST 5,000 AND SPECIALIST American Diabetes Association TRANSITIONS OF CARE THROUGH THE DIABETES LIFESPAN 5,000 American Society of Nephrology ASN BOARD REVIEW COURSE AND UPDATE 15,000 American Society of Nephrology CALCIUM OR NO CALCIUM: THAT IS THE QUESTION 125,825 American Urological Association ESTABLISHING AN ADVANCED PROSTATE CANCER CLINIC: A 60,000 Education & Research, Inc. PRACTICAL GUIDE FOR THE UROLOGY CLINIC Association of Family Practice JOINT ASPIRATION/INJECTION WORKSHOP 5,300 Physician Assistants Cardiovascular Society of Buffalo and UNDERSTANDIJG FABRY DISEASE FROM A CARDIAC PERSPECTIVE 7,000 Western NY SUNY AT BUFFALO CME OFFICE Cleveland Clinic Educational CURRENT AND FUTURE THERAPEUTIC OPTIONS TARGETING 80,000 Foundation RESIDUAL CVD RISK: EMERGING THERAPIES FOR THE Collaboration \3\ TREATMENT OF DYSLIPIDEMIA CME Outfitters, LLC RISKY BUSINESS: UNDERSTANDING AND ATTENUATING RISK 207,090 ASSOCIATED WITH DISEASE-MODIFYING THERAPY IN RELAPSING-REMITTING MULTIPLE SCLEROSIS Consortium of Multiple Sclerosis EXPERT DEBATES IN MULTIPLE SCLEROSIS: OPPOSING VIEWS 125,000 Centers Nurse Practitioner IN MANAGEMENT Alternatives Consortium of Multiple Sclerosis PATIENTGPS?: CLINICAL PATHS TO EXPLORE TREATMENT 100,000 Centers Nurse Practitioner OPTIONS AND INDIVIDUALIZE THERAPY IN MULTIPLE Alternatives SCLEROSIS Dignity Health MandatoryCE LLC 2ND ANNUAL NEW MEXICO REGIONAL DIABETES SYMPOSIUM 45,000 FORE 2015 ORTHOPAEDICS FOR THE PRIMARY CARE PRACTITIONER & 4,000 REHABILITATION THERAPIST Humboldt-Del Norte Consortium for MULTIPLE SCLEROSIS 4,100 Continuing Medical Education Icahn School of Medicine at Mount MULTIPLE SCLEROSIS AND ITS MIMICS 1,920 Sinai Icahn School of Medicine at Mount ADVANCES IN PEDIATRIC FOOD ALLERGY 15,000 Sinai Institute for the Advancement of LEARNER-DIRECTED CME: WHAT DO PRIMARY CARE PROVIDERS 49,500 Human Behavior Answers in CME, Inc. NEED TO KNOW ABOUT THE LATEST ADVANCES IN THE TREATMENT HYPERCHOLESTEROLEMIA Johns Hopkins University Advanced THE 11TH ANNUAL JOHNS HOPKINS MULTIPLE SCLEROSIS 210,000 Studies in Medicine SYMPOSIUM SERIES Johns Hopkins University Advanced COMPREHENSIVE CARE FOR PATIENTS WITH GAUCHER DISEASE: 195,100 Studies in Medicine EMERGING CONCEPTS FOR IMPROVED OUTCOMES Johns Hopkins University Medical MANAGEMENT OF PERSISTENT HYPERGLYCEMIA IN TYPE 2 81,750 Logix, LLC DIABETES: BEYOND STARTING DOSES OF BASAL INSULIN Medical Education Resources Tarsus THE EVOLUTION OF INSULIN THERAPY: NEW DEVELOPMENTS IN 100,000 Cardio Inc. dba Health Science Media TREATMENT, TECHNOLOGY, AND METHODS OF ADMINISTRATION Medical Learning Institute, Inc. PEERVIEW INREVIEW, RISING TO THE CHALLENGE: FOSTERING 100,000 PeerView Institute for Medical EFFECTIVE PATIENTPROVIDER COMMUNICATION THROUGHOUT Education, Inc. THE COURSE OF POMPE DISEASE Medical University of South Carolina 1ST ANNUAL NEPHROLOGY TRANSPLANT SYMPOSIUM FOR 2,500 NEPHROLOGISTS, PRIMARY CARE AND HOSPITALISTS Med-IQ, LLC TARGETING MODERATE-TO-SEVERE ATOPIC DERMATITIS: 99,896 EVOLVING TREATMENT STRATEGIES TO ADDRESS A KEY UNMET Collaboration \3\ MEDICAL NEED Med-IQ, LLC CASE SIMULATIONS IN TUMOR LYSIS SYNDROME: AGGRESSIVE 100,000 PROPHYLAXIS STRATEGIES TO PREVENT ADVERSE PATIENT OUTCOMES Med-IQ, LLC UPDATE FOR CLINICIANS: THE POTENTIAL OF IL-6 104,578 INHIBITORS TO REVOLUTIONIZE RHEUMATOID ARTHRITIS Collaboration \3\ TREATMENT Medscape, LLC A PRACTICAL GUIDE TO THE PREVENTION OF SURGICAL 160,000 ADHESIONS Medscape, LLC IDENTIFYING AND ADDRESSING INADEQUATELY MANAGED 138,500 OSTEOARTHRITIS PAIN Medscape, LLC GLP-1 RECEPTOR AGONISTS IN T2D MANAGEMENT: THE MODERN 105,100 INJECTABLE Missouri Academy of Physician THE GOOD, THE BAD, AND THE IATROGENIC? 3,500 Assistants Missouri Academy of Physician JOINT INJECTIONS 5,000 Assistants Montefiore Medical Center PlatformQ A COMPREHENSIVE PERSPECTIVE ON INSULIN REPLACEMENT FOR 100,000 Health Education, LLC TYPE 2 DIABETES Montefiore Medical Center PlatformQ MULTIPLE SCLEROSIS: EXPLORING TREATMENT OPTIONS AND 85,000 Health Education, LLC INDIVIDUALIZING THERAPY National Association of Managed Care ADVANCES IN THE MANAGEMENT OF MULTIPLE SCLEROSIS: A 57,000 Physicians, Inc. CLOSER LOOK AT NOVEL THERAPIES National Association of Managed Care INDIVIDUALIZING TREATMENT STRATEGIES FOR EFFECTIVE A1C 57,000 Physicians, Inc. REDUCTION AND IMPROVED OUTCOMES IN TYPE 2 DIABETES National Jewish Health California CSAAI 23RD ANNUAL EDUCATIONAL MEETING 10,000 Society of Allergy, Asthma and Collaboration \3\ Immunology National Kidney Foundation, Inc. GREENSBORO PATIENT EMPOWERMENT WORKSHOP 3,500 National Kidney Foundation, Inc. CHRONIC KIDNEY DISEASE & THE PRIMARY CARE 25,000 PRACTITIONER: EARLY SCREENING AND PREVENTION FOR THE AT-RISK PATIENT National Kidney Foundation, Inc. 11TH ANNUAL JOINT MEETING OF THE UPSTATE AND WESTERN 5,000 NEW YORK COUNCILS ON RENAL NUTRITION National Medical Association NEW TYPE 2 DIABETES GUIDELINES AND THE TREND TOWARD 100,000 NEWER PHARMACOLOGICAL TREATMENT North American Center for Continuing IMPLEMENTING BEST PRACTICES FOR TUMOR LYSIS SYNDROME 100,000 Medical Education, LLC Horizon CME, Inc. Not-For-Profit Hospital Corporation CHRONIC KIDNEY DISEASE: STATE OF THE ART 2015 1,900 Pennsylvania Academy of Family PA ACADEMY OF FAMILY PHYSICIANS FOUNDATION A1C 150,000 Physicians Foundation CHALLENGE Pennsylvania Society of Physician THYROID MASSES 8,400 Assistants Pharmacy Times Office of Continuing CONVENIENT CARE OPPORTUNITIES TO OPTIMIZING INSULIN 48,689 Professional Education THERAPY IN TREATMENT OF TYPE 2 DIABETES Pharmacy Times Office of Continuing AJPB QUALITY FORUM: IMPLEMENTATION OF QUALITY MEASURES 50,000 Professional Education PQA, Inc. TO IMPROVE OUTCOMES IN DYSLIPIDEMIA Collaboration \3\ Pharmacy Times Office of Continuing AJPB QUALITY FORUM: AIMING FOR A FIVE-STAR RATING IN 50,000 Professional Education PQA, Inc. DIABETES CARE: MANAGED CARE PLANS AND COMMUNITY PHARMACIST COLLABORATION Postgraduate Healthcare Education, ADDRESSING HYPOGLYCEMIA IN TYPE 2 DIABETES MELLITUS: 30,000 LLC Medical Logix, LLC THE PHARMACISTS ROLE IN OPTIMIZING PATIENT OUTCOMES Postgraduate Institute for Medicine C- NOVEL MECHANISMS AND ADVANCING THERAPEUTIC PARADIGMS 379,000 MEducation Resources, LLC FOR OPTIMIZING LDL-FOCUSED MANAGEMENT AND Collaboration \3\ CARDIOPROTECTION IN THE DIABETIC PATIENT Postgraduate Institute for Medicine C- THE IQ&A INTERACTIVE CARDIOVASCULAR INTELLIGENCE ZONE: 238,100 MEducation Resources, LLC NEW FRONTIERS IN LDL-TARGETED CV RISK REDUCTION Collaboration \3\ Preventive Cardiovascular Nurses 2015 FALL LEARNING SERIES 35,000 Association PRIME Education Inc. (PRIME) CASE-BASED DEBATES ABOUT UTILITY OF PCSK9 INHIBITORS 123,000 IN PATIENT POPULATIONS FOR LIPID REDUCTION Collaboration \3\ PRIME Education Inc. (PRIME) INTERNATIONAL INSIGHTS ON TREATMENT ADVANCES FOR 166,077 RHEUMATOID ARTHRITIS Collaboration \3\ PRIME Education Inc. (PRIME) NEW CHALLENGES IN THE PREVENTION AND MANAGEMENT OF 78,810 TUMOR LYSIS SYNDROME IN PATIENTS WITH CHRONIC LYMPHOCYTIC LEUKEMIA Pri-Med Institute, LLC (d/b/a pmiCME) DYSLIPIDEMIA IN PRIMARY CARE: NEW GUIDELINE 250,000 Horizon CME, Inc. RECOMMENDATIONS AND TREATMENT OPTIONS Collaboration \3\ ProCE, Inc. Institute for Safe CONCENTRATED INSULIN: SAFE USE IN THE HOSPITAL AND 102,233 Medication Practices TRANSITIONS OF CARE Projects In Knowledge, Inc. MULTIPLE SCLEROSIS @ POINT OF CARE 200,000 Regents of the University of Colorado RENAL DISEASE & ELECTROLYTE DISORDERS COURSE 3,000 Regents of the University of Colorado PEDIATRIC AND ADULT DIFFERENTIATED THYROID CANCER, ARE 75,000 American Thyroid Association THEY DIFFERENT? Regents, University of California THIRD ANNUAL UCLA REVIEW OF CLINICAL NEUROLOGY 15,000 Rush University Medical Center Plexus DEVELOPING AN INTEGRATIVE APPROACH TO METASTATIC 65,000 Communications PROSTATE CANCER: MAKING IT PERSONAL TO IMPROVE CLINICAL OUTCOMES Rutgers, The State University of New 8TH ANNUAL PERSPECTIVES IN RHEUMATIC DISEASES, 10,000 Jersey Global Academy for Medical PRESENTED BY RHEUMATOLOGY NEWS, INTERNAL MEDICINE Collaboration \3\ Education, LLC NEWS, FAMILY PRACTICE NEWS South Dakota Academy of Physician DIABETIC MANAGEMENT 3,500 Assistants Tennessee Academy of Physician FALLFEST 2015-RENAL DISEASE 2,500 Assistants Texas A&M University System Health 11TH ANNUAL DIABETES CONFERENCE 10,000 Science Center Coastal Be The Boston Home CARING FOR THE PATIENT WITH ADVANCED MULTIPLE 10,000 SCLEROSIS The Endocrine Society UPDATE IN BASAL INSULINS: YOUR QUESTIONS ANSWERED 129,040 The Endocrine Society 2015 CLINICAL ENDOCRINOLOGY UPDATE 25,000 The Endocrine Society 2015 CLINICAL ENDOCRINOLOGY UPDATE 25,000 The France Foundation MS CLINICAL DIALOGS: A PEER DISCUSSION ON OPTIMAL 76,547 TREATMENT (PHASE 2) The France Foundation National A MULTI-DISCIPLINARY APPROACH TO LIMB-GIRDLE MUSCLE 240,794 Society of Genetic Counselors WEAKNESS DYSTROPHY AND RELATED CONDITIONS MANAGEMENT The Medical College of Wisconsin, INTERACTIVE UPDATES IN USE OF STEM CELL MOBILIZATION 120,000 Inc. Carden Jennings Publishing Co., FOR THE TREATMENT OF BLOOD RELATED CANCERS Ltd. Ultimate Medical Academy, LLC dba IMPROVING OUTCOMES IN RHEUMATOID ARTHRITIS: TREATING 162,588 Global Education Group Integritas TO TARGET, IL-6-DIRECTED THERAPIES, AND EVOLVING Collaboration \3\ Communications, LLC MANAGEMENT ALGORITHMS UMA MLG, LLC THE CHANGING LANDSCAPE OF DYSLIPIDEMIA TREATMENT 198,900 Collaboration \3\ UMA MLG, LLC A 3-DIMENSIONAL VIEW INTO THE ROLE OF GLP1 IN TYPE-2 30,000 DIABETES: EXPLORING EVIDENCE-BASED GUIDELINES AS PATIENT-CENTERED THERAPY University of California, San Diego PROMOTING BEHAVIOR CHANGE IN DIABETES: A SKILL 50,000 Behavioral Diabetes Institute BUILDING PROGRAM FOR HEALTH CARE PROFESSIONALS A University of Cincinnati Global THE KNEE COURSE 2015 19,500 Academy for Medical Education, LLC University of Virginia Renal RENAL PHYSICIANS ASSOCIATION 2015 ADVANCED 12,500 Physicians Association PRACTITIONER CONFERENCE ---------------------------------------------------------------------------------------------------------------- \1\ Applicant names are provided by the requestor. If applicants apply as a group for a single educational activity; all applicants may be not be identified above. The Company funds other educational activities (including fellowships and non-physician and patient education); all of which do not appear on this report, but appear on other reports on this site. \2\ ``Funding Amount'' is the amount that the Company funded during Q3, 2015 identified above based upon an agreement. Recipients are required to return any unused funds. Information on unused funds returned by the applicant on activities are not reported. ``Funding Amount'' does not include funds that may have been provided by other affiliated Sanofi Company Entities (e.g., Sanofi Pasteur). \3\ Collaboration (Shared) Funding--is the full amount of a grant funded under an agreement with Regeneron, some or all of which may be shared between the collaborating entities. Independent Medical Education Grants 1st Oct 2015-31st Dec 2015 Sanofi US and its affiliate Genzyme Corporation are committed to supporting independent medical education activities in therapeutic areas in which the Company is involved, for healthcare professionals, patients, and consumers to improve patient care and health outcomes in therapeutic areas in which the Company is engaged. Sanofi US and Genzyme Corporation are part of the Sanofi Group, a global pharmaceutical company. ---------------------------------------------------------------------------------------------------------------- Funding Amount Recipient Name(s) \1\ Activity Title ($) \2\ ---------------------------------------------------------------------------------------------------------------- American Academy of Physician 2015 ADULT HOSPITAL MEDICINE BOOT CAMP 2,500 Assistants American Association of Clinical NEW ENGLAND CHAPTER OF AACE 7TH ANNUAL MEETING 5,000 Endocrinologists American Association of Clinical DIABETES DAY FOR PRIMARY CARE CLINICIANS EDUCATIONAL 50,000 Endocrinologists SERIES American Neurological Association 2015 AMERICAN NEUROLOGICAL ASSOCIATION 140TH ANNUAL 25,000 MEETING ANNA Chapter 125, 126, and 133 ANNA NJ COLLABORATIVE 2015 3,000 Annenberg Center for Health Sciences INITIATING AND ADVANCING MULTIPLE SCLEROSIS THERAPIES: 125,000 at Eisenhower Postgraduate Institute IMPROVING PATIENT CARE AND HEALTH OUTCOMES for Medicine Baylor University Medical Center dba FOLLOWING THE EVIDENCE A PRACTICAL, CASE BASED 45,975 A. Webb Roberts Center MedNet, LLC APPROACH TO PERSONALIZED TREATMENT OPTIONS FOR MULTIPLE SCLEROSIS California Optometric Association 2015 MONTEREY SYMPOSIUM 7,416 Cedars-Sinai Medical Center 5TH ANNUAL SYMPOSIUM ON LYSOSOMAL STORAGE DISORDERS 26,010 Consortium of Multiple Sclerosis 4TH CONFERENCE OF THE INTERNATIONAL MS COGNITION 56,280 Centers Nurse Practitioner SOCIETY IN COLLABORATION WITH THE CONSORTIUM OF Alternatives MULTIPLE SCLEROSIS CENTERS Harris County Optometric Society EYES ON FABRY HARRIS COUNTY OPTOMETRIC SOCIETY 7,000 Fabry Support & Information Group Horizon CME, Inc. STRATEGIES FOR SELECTION AND OPTIMAL SEQUENCING OF 85,000 CURRENT TREATMENT OPTIONS FOR METASTATIC CASTRATION- RESISTANT PROSTATE CANCER Icahn School of Medicine at Mount 3RD NY MASTERS COURSE IN ENDOCRINOLOGY AND ENDOCRINE 15,000 Sinai SURGERY Indiana Academy of Physician THE GOOD, THE BAD AND THE IATROGENIC (RENAL MEDICATION 3,250 Assistants DOSING) Letters & Sciences ADVANCES IN MS RESEARCH & PRACTICE 2015 ANNUAL 70,000 CONFERENCE Medical Education Resources Tarsus 2015 CMHC SYMPOSIUM: NOVEL THERAPIES FOR LDL-C 40,000 Cardio Inc. dba Health Science Media LOWERING IN THE FIGHT AGAINST RESIDUAL ASCVD RISK Medical Learning Institute, Inc. PEERVIEW IN EXCHANGE, ESTABLISHING BEST PRACTICES FOR 140,325 PeerView Institute for Medical THE PERSONALIZED CARE OF PATIENTS WITH MULTIPLE Education, Inc. SCLEROSIS: A TIMELY DISCUSSION AMONG ADVANCED PRACTICE CLINICIANS? Medical Learning Institute, Inc. PEERVIEW VIDEO IN SESSION, CLINICAL HIGHLIGHTS FROM 134,450 PeerView Institute for Medical BARCELONA: AN UP-TO-DATE REVIEW OF NEW DATA ON Education, Inc. APPROVED DISEASE-MODIFYING THERAPIES FOR MULTIPLE SCLEROSIS MANAGEMENT? Medical Learning Institute, Inc. 2016 ACMG--PEERVIEW LIVE, ENSURING THE RAPID 239,950 PeerView Institute for Medical IDENTIFICATION AND INDIVIDUALIZED MANAGEMENT OF Education, Inc. GAUCHER DISEASE TYPE 1: KEY PRINCIPLES AND STRATEGIES Med-IQ, LLC NEW THERAPIES FOR GAUCHER'S DISEASE: TALK TO YOUR 147,396 PHARMACIST Med-IQ, LLC EARLIER RECOGNITION AND TREATMENT OF GAUCHER'S DISEASE 135,728 IN HEMATOLOGY CLINICS Med-IQ, LLC RECOGNIZING THE UNLIKELY: IMPROVING IDENTIFICATION AND 246,977 CARE OF FABRY DISEASE Michigan State Medical Society CARDIOVASCULAR DISEASE IN PATIENTS WITH RENAL DISEASE 2,500 National Jewish Health 38TH ANNUAL PULMONARY AND ALLERGY UPDATE 10,000 Collaboration \3\ National Jewish Health Western WSAAI 54TH ANNUAL SCIENTIFIC SESSION 10,000 Society of Allergy, Asthma and Collaboration \3\ Immunology (WSAAI) National Kidney Foundation, Inc. NATIONAL KIDNEY FOUNDATION'S 47TH ANNUAL MEDICAL 2,500 SYMPOSIUM National Multiple Sclerosis Society Research Symposium 2015: MS Research Discoveries: 3,000 New York Chapter Wellness and Treatments for Living Your Best Life Pennsylvania Society of Physician RENAL MEDICATION DOSING: THE GOOD, THE BAD, AND THE 4,000 Assistants IATROGENIC PESI, Inc. Metabolic Endocrine 13TH ANNUAL WORLD CONGRESS ON INSULIN RESISTANCE, 15,000 Education Foundation DIABETES AND CARDIOVASCULAR DISEASE--WCIRDC Collaboration \3\ Postgraduate Institute for Medicine FAILURE IS NOT AN OPTION: SELECTING OPTIMAL STEM CELL 205,195 AXIS Medical Education, Inc. MOBILIZATION STRATEGIES FOR MULTIPLE MYELOMA AND NON- HODGKIN LYMPHOMA Postgraduate Institute for Medicine 1,800 SECONDS? IN DIABETES MANAGEMENT WITH A GLP-1 75,000 Catamount Medical Education, LLC RECEPTOR AGONIST AND BASAL INSULIN Projects In Knowledge, Inc. MedPage CLINICAL CONTEXT: MULTIPLE SCLEROSIS 131,000 Today, LLC Rutgers, The State University of New THE FOURTH EVIDENCE-BASED PEDIATRIC UPDATE SYMPOSIUM 5,000 Jersey Rutgers, The State University of New SKIN DISEASE EDUCATION FOUNDATION'S 16TH ANNUAL LAS 5,000 Jersey Global Academy for Medical VEGAS DERMATOLOGY SEMINAR, FEATURING THE 12TH ANNUAL Collaboration \3\ Education, LLC PSORIASIS FORUM Society of Nuclear Medicine SNMMI 2015-2016 THYROID IMAGING AND THERAPY 108,730 EDUCATIONAL OUTREACH FOR REFING PHYSICIANS AND IMAGING PHYSICIANS Swedish Medical Center Foundation FIFTH ANNUAL INTENSIVE UPDATE IN NEUROLOGY 10,000 Swedish Medical Center Foundation DIABETES MANAGEMENT UPDATE 2015 8,000 The Board of Trustees of the UA for SPECIAL NEPHROLOGY RESEARCH AND TRAINING CENTER 15,000 the UA at Birmingham SYMPOSIUM--11/9/15 The University of Texas Southwestern NEUROTHERAPEUTICS UPDATE 5,000 Medical Center at Dallas Tufts University School of Medicine IMPROVING CARE FOR HEART FAILURE PATIENTS: AN UPDATE 5,000 FOR HEALTHCARE PROVIDERS - THE 8TH ANNUAL NEW ENGLAND HEART FAILURE AND TRANSPLANT NETWORK CONFERENCE University of Massachusetts Medical NEW FRONTIERS AND EMERGING TREATMENT PARADIGMS FOR 347,000 School C-MEducation Resources, LLC OPTIMIZING LDLTARGETED CARDIOVASCULAR RISK REDUCTION Collaboration \3\ University of Massachusetts Medical THE IQ&A INTERACTIVE RHEUMATOID ARTHRITIS INTELLIGENCE 189,000 School C-MEducation Resources, LLC ZONE: FOCUS ON THE EVIDENCE BASIS FOR RA MANAGEMENT Collaboration \3\ THROUGH INHIBITION OF THE IL-6 CYTOKINE AND OTHER FOUNDATION SIGNALING SYSTEMS University of Massachusetts Medical NEW FRONTIERS AND TREATMENT ADVANCES FOR ATOPIC 360,000 School C-MEducation Resources, LLC DERMATITIS: FOCUS ON THE ROLE OF ESTABLISHED AND Collaboration \3\ EVOLVING BIOLOGIC THERAPIES FOR PEDIATRIC AND ADULT PATIENTS WITH MODERATE-TO-SEVERE AND TREATMENT- RESISTANT ATOPIC DERMATITIS University of Texas Health Science AMDA INTERNATIONAL PATIENT AND SCIENTIFIC CONFERENCE-- 60,000 Center at San Antonio Acid Maltase PAST, PRESENT, FUTURE Deficiency Association, Inc. Vindico Medical Education, LLC IN SEARCH OF THE GUIDING LIGHT: RE-VISITING THE USE OF 372,524 ORAL AND HIGHEFFICACY THERAPIES IN A MODERN ERA OF MULTIPLE SCLEROSIS TREATMENT ---------------------------------------------------------------------------------------------------------------- \1\ Applicant names are provided by the requestor. If applicants apply as a group for a single educational activity; all applicants may be not be identified above. The Company funds other educational activities (including fellowships and non-physician and patient education); all of which do not appear on this report, but appear on other reports on this site. \2\ ``Funding Amount'' is the amount that the Company funded during Q4, 2015 identified above based upon an agreement. Recipients are required to return any unused funds. Information on unused funds returned by the applicant on activities are not reported. ``Funding Amount'' does not include funds that may have been provided by other affiliated Sanofi Company Entities (e.g., Sanofi Pasteur). \3\ Collaboration (Shared) Funding--is the full amount of a grant funded under an agreement with Regeneron, some or all of which may be shared between the collaborating entities. Independent Medical Education Grants 1st Jan 2016-31th Mar 2016 Sanofi US and its affiliate Genzyme Corporation are committed to supporting independent medical education activities in therapeutic areas in which the Company is involved, for healthcare professionals, patients, and consumers to improve patient care and health outcomes in therapeutic areas in which the Company is engaged. Sanofi US and Genzyme Corporation are part of the Sanofi Group, a global pharmaceutical company. ---------------------------------------------------------------------------------------------------------------- Funding Amount Recipient Name(s) \1\ Activity Title ($) \2\ ---------------------------------------------------------------------------------------------------------------- Admin of the Tulane Educa Fund on 8TH ANNUAL TULANE SYMPOSIUM ON THYROID AND PARATHYROID 7,500 behalf of TUHSC CCE DISEASES AKH Inc Advancing Knowledge and 2016 SOUTH BEACH SYMPOSIUM: CLINICAL DERMATOLOGY 5,000 Healthcare SYMPOSIUM Collaboration \3\ AKH Inc Advancing Knowledge and NOVEL MECHANISMS AND ADVANCING THERAPEUTIC PARADIGMS 336,000 Healthcare C-MEducation Resources, FOR OPTIMIZING LDLFOCUSED MANAGEMENT AND CV RISK Collaboration \3\ LLC REDUCTION IN THE DIABETIC PATIENT American Academy of Continuing INCREASING ACCESS TO KIDNEY TRANSPLANTATION: NOVEL 104,000 Medical Education, Inc. Spire STRATEGIES TO EXPAND LIVING DONATION Learning American Association of Clinical THYROID SESSIONS AT ENDOCRINE UNIVERSITYr: DISEASE 30,000 Endocrinologists MANAGEMENT & TECHNOLOGY SKILLS FOR ENDOCRINOLOGY FELLOWS IN TRAINING American Association of Clinical NEVADA AACE THYROID CANCER SYMPOSIUM 5,000 Endocrinologists American Association of Clinical LDL-C REDUCTION IN THE PATIENT WITH DIABETES: HOW LOW 267,758 Endocrinologists Medtelligence, LLC SHOULD WE GO AND HOW SHOULD WE GET THERE? Collaboration\3\ American College of Cardiology DYSLIPIDEMIA COMBO-THERAPY: A FRAMEWORK FOR CLINICAL 75,000 Foundation DECISION-MAKING Collaboration\3\ American College of Rheumatology 2016 ACR RHEUMATOLOGY COURSES 150,000 Collaboration \3\ American Health Resources, Inc. EXAMINING THE ROLE OF PCSK9 INHIBITORS IN DYSLIPIDEMIA 4,200 MANAGEMENT Collaboration \3\ American Kidney Fund AMERICAN KIDNEY FUND 2016 CLINICAL SCIENTIST IN 75,000 NEPHROLOGY PROGRAM American Society of Transplant ASTS 16TH ANNUAL STATE OF THE ART WINTER SYMPOSIUM: 50,000 Surgeons LIMITED SUPPLY, INCREASING DEMAND: EXPANDING ORGAN DONATION Annenberg Center for Health Sciences EXPERTS IN RESIDENCE: BRIDGING THE GAP FROM KNOWLEDGE 110,000 at Eisenhower TO PRACTICE IN CASTRATION-RESISTANT PROSTATE CANCER Association of Black Cardiologists, EVOLVING STRATEGIES FOR CARDIOVASCULAR RISK REDUCTION: 350,000 Inc. National Association for BEYOND STATIN THERAPY Collaboration \3\ Continuing Education Cardiovascular Center of Sarasota 12TH ANNUAL CARDIOVASCULAR SYMPOSIUM CARDIOLOGY UPDATE 5,000 Foundation for Research and Florida 2016: FROM INTERVENTION TO PREVENTION TIME TO FOCUS Collaboration \3\ Medical Association ON EARLY CARDIOVASCULAR HEALTH Cardio Renal Society of America 4th ANNUAL CARDIO-RENAL METABOLIC CONFERENCE 6,000 CME Outfitters, LLC IMPLEMENTING PERSONALIZED ACTION PLANS FOR PATIENTS 99,867.5 WITH ATOPIC DERMATITIS Collaboration \3\ Consortium of Multiple Sclerosis CLINICIAN-PATIENT SHARED DECISION MAKING IN MS: AN 100,860 Centers Nurse Practitioner ESSENTIAL STEP TOWARD BETTER OUTCOMES Alternatives Emory University EVALUATION OF THE LGMD DIAGNOSTIC TESTING PROGRAM: 5,850 PROGRAM UPDATES, OPPORTUNITIES AND FUTURE WORK Forefront Collaborative National CURRENT CONTROVERSIES IN DYSLIPIDEMIA MANAGEMENT: A 85,000 Lipid Association POINT-COUNTERPOINT DISCUSSION Collaboration \3\ Medical Learning Institute, Inc. UNDERSTANDING THE EVOLUTION OF MS CARE: OPTIMIZING 43,186 THERAPEUTIC DECISION MAKING Medical Learning Institute, Inc. PEERVIEW INCLINIC, ``MAXIMIZING CARE FOR INDIVIDUALS 145,000 PeerView Institute for Medical WITH MULTIPLE SCLEROSIS: THE ROLE OF Education, Inc. INTERPROFESSIONAL EDUCATION'' Medical Learning Institute, Inc. PEERVIEW LIVE, "DISRUPTING DISEASE WORSENING IN 296,820 PeerView Institute for Medical PATIENTS WITH MS: HOW CAN WE HARNESS THE FULL Education, Inc POTENTIAL OF AVAILABLE DISEASE-MODIFYING Med-IQ, LLC WHEN INSULIN ALONE ISN'T THE ANSWER: A FOCUSED LOOK AT 257,768 COMBINING BASAL INSULIN AND GLP-1 RECEPTOR AGONISTS Med-IQ, LLC HOW EARLY IS EARLY? WHEN TO START ERT AND OTHER 160,522 CONSIDERATIONS FOR OPTIMIZING TREATMENT OF FABRY DISEASE National Association of Managed Care EFFECTIVE A1C REDUCTION IN TYPE 2 DIABETES: A CLOSER 75,000 Physicians, Inc. LOOK AT COMBINATION INSULIN THERAPY National Kidney Foundation, Inc. CKD-MBD: STATE-OF-THE-ART CONSIDERATIONS FOR OPTIMAL 253,850 University of Illinois at Chicago OUTCOMES National Lipid Association NATIONAL LIPID ASSOCIATION 2016 MASTERS IN LIPIDOLOGY 20,000 COURSE SERIES Collaboration \3\ National Lipid Association NATIONAL LIPID ASSOCIATION 2016 LIPID ACADEMY COURSE 20,000 SERIES Collaboration \3\ Nebraska Academy of Physician JOINT INJECTION WORKSHOP 5,100 Assistants Nevada System of Higher Education 2016 WINTER CLINICAL DERMATOLOGY CONFERENCE--HAWAII 50,000 Foundation for Research and Collaboration \3\ Education in Dermatology North American Center for Continuing MEETING THE UNMET NEEDS OF PATIENTS WITH 415,000 Medical Education, LLC Horizon CME, HYPERCHOLESTEROLEMIA: A FOCUS ON PCSK9 INHIBITORS Collaboration \3\ Inc. NYU School of Medicine SEMINAR IN ADVANCED RHEUMATOLOGY 20,000 Collaboration \3\ NYU School of Medicine 41ST ANNUAL COMPREHENSIVE REVIEW OF PHYSICAL MEDICINE 5,000 AND REHABILITATION Pharmacy Times Office of Continuing COST-EFFECTIVENESS OF DISEASE-MODIFYING THERAPIES IN 89,160 Professional Education MULTIPLE SCLEROSIS: A MANAGED CARE PERSPECTIVE Pharmacy Times Office of Continuing INNOVATION AND CLINICAL ADVANCES IN ACHIEVING GLYCEMIC 240,728 Professional Education CONTROL: EVALUATING THE EFFICACY OF COMPLIMENTARY AGENTS Pharmacy Times Office of Continuing THE ROLE OF THE PHARMACIST IN ACHIEVING TIGHT GLYCEMIC 53,346 Professional Education CONTROL IN TYPE 2 DIABETES: PROMOTING PATIENT SELF- MONITORING AND AGGRESSIVE TREATMENT Physicians' Education Resource, LLC 2016 NEW YORK GUTM: 9TH ANNUAL INTERDISCIPLINARY 75,000 PROSTATE CANCER CONGRES Postgraduate Healthcare Education, OPTIMIZED APPROACHES TO INSULIN THERAPY AND GLUCOSE 301,000 LLC CONTROL IN TYPE 2 DIABETES Postgraduate Institute for Medicine C- NEW THERAPEUTIC ADVANCES AND PRACTICAL STRATEGIES FOR 309,500 MEducation Resources, LLC COMPLEMENTARY BASAL INSULIN PLUS INCRETIN SYSTEM- TARGETED THERAPY TO OPTIMIZE GLUCOSE CONTROL Postgraduate Institute for Medicine C- NEW THERAPEUTIC ADVANCES AND PRACTICAL STRATEGIES FOR 331,000 MEducation Resources, LLC COMPLEMENTARY BASAL INSULIN PLUS INCRETIN SYSTEM- TARGETED THERAPY IN COMPLEX PATIENTS WITH Primary Care Education Consortium COMBINING A GLUCAGON-LIKE PEPTIDE-1 RECEPTOR AGONIST 309,985 WITH BASAL INSULIN: THE WHY AND HOW PRIME Education Inc (PRIME) NEW TREATMENT GUIDELINES, EVIDENCE, AND AGENTS IN 249,505 RHEUMATOID ARTHRITIS Collaboration \3\ Pri-Med Institute, LLC (d/b/a pmiCME) HOW TO SELECT AND INITIATE INSULIN THERAPY IN THE TYPE 998,500 Horizon CME, Inc. 2 DIABETES PATIENT Pri-Med Institute, LLC (d/b/a pmiCME) GLP-1 RECEPTOR AGONISTS AND BASAL INSULIN COMBINATION: 977,000 Horizon CME, Inc. AN COMPLEMENTARY STRATEGY FOR TYPE 2 DIABETES TREATMENT INTENSIFICATION Projects In Knowledge, Inc. MEDIMAGE CASES: MULTIPLE SCLEROSIS 125,000 Rhode Island Hospital, CME ENDOCRINE GRAND ROUNDS 10,000 Rutgers, The State University of New SKIN DISEASE EDUCATION FOUNDATION'S 40TH ANNUAL HAWAII 10,000 Jersey Global Academy for Medical DERMATOLOGY SEMINAR Collaboration \3\ Education, LLC ScientiaCME, LLC Specialty Pharma PROSTATE CANCER: ADVANCES IN PATIENT MANAGEMENT & 14,875 Education Center TREATMENT OPTIONS Scripps Health SCRIPPS WHITTIER DIABETES INSTITUTE'S PROJECT DULCE 50,000 The Endocrine Society Advanced THE EFFECTIVE USE OF INSULIN IN TYPE 2 DIABETES: A 329,613 Studies in Medicine FOCUS ON TREATMENT ADVANCES The Endocrine Society Institute for DIABETES MASTERS SERIES 2016: INITIATING THE 237,055.5 Medical and Nursing Education CONVERSATION: SHARING PERSPECTIVES ON ADVANCES IN T2DM TREATMENT TO IMPROVE PATIENT-CENTERED CARE The Endocrine Society Scripps Health NEW COMPLEMENTARY INSULIN COMBINATIONS TO ACHIEVE 361,515 HBA1C TARGETS: 2016 ENDOCRINE SOCIETY ANNUAL CONVENTION SATELLITE SYMPOSIUM The Massachusetts General Hospital CLINICAL ENDOCRINOLOGY 2016 5,000 The Medical College of Wisconsin, NEW TITORY FOR THE UROLOGIST: OPTIMAL MONITORING AND 150,000 Inc. Paradigm Medical TREATMENT SELECTION FOR MCRPC Communications, LLC The Medical College of Wisconsin, OPTIMIZING STEM CELL MOBILIZATION STRATEGIES TO 299,980 Inc. PeerView Institute for Medical ENHANCE SUCCESS OF AUTOLOGOUS HEMATOPOIETIC STEM CELL Education, Inc. TRANSPLANTATION The Vitamin D Workshop Inc. THE 19TH WORKSHOP ON VITAMIN D 5,000 Trustees of Boston University PCE DIRECTED LEARNING ECOURSE: A MULTIMODAL APPROACH 152,105 Continuing Education Alliance, LLC TO MANAGING KNEE OSTEOARTHRITIS Trustees of the University of 2016 THYROID MASTER CLASS: MANAGEMENT OF ADVANCED 10,000 Pennsylvania/CME (PROGRESSIVE MEDULLARY AND RAI-REFRACTORY DIFFERENTIATED) THYROID CANCER AND UPDATE IN THYROID/ PARATHYROID ULTRASOUND IMAGING University of Cincinnati PeerView PEERVIEW INREVIEW, ``ACHIEVING RAPID CONTROL OF 68,700 Institute for Medical Education, DISEASE ACTIVITY IN PATIENTS WITH MULTIPLE SCLEROSIS: Inc. THE INCREASINGLY IMPORTANT ROLE OF DISEASEMODIFYING'' University of Massachusetts Medical THE PHYSIOLOGIC BASIS FOR OPTIMIZING GLYCEMIC CONTROL 331,000 School C-MEducation Resources, LLC WITH BASAL INSULIN IN COMPLEX PATIENTS WITH DIABETES University of Massachusetts Medical THE FOUNDATIONAL ROLE AND PHYSIOLOGIC BASIS FOR 305,600 School C-MEducation Resources, LLC OPTIMIZING GLYCEMIC CONTROL WITH LONG-ACTING INSULINS: FOCUS ON THE SAFETY-EFFICACY PROFILES OF NEW University of Massachusetts Medical NEW FRONTIERS AND CLINICAL ADVANCES IN IMMUNOTHERAPY 389,000 School C-MEducation Resources, LLC FOR ASTHMA: FOCUS ON BIOLOGICS-BASED MANAGEMENT OF Collaboration \3\ MODERATE-TO-SEVERE ASTHMA IN PATIENTS University of Virginia RENAL PHYSICIANS ASSOCIATION 2016 ANNUAL MEETING 25,000 University of Virginia RENAL PHYSICIANS ASSOCIATION ADVANCED PRACTITIONER 7,500 CONFERENCE Yale University Research To Practice CURRENT STRATEGIES AND ONGOING RESEARCH IN THE 80,000 MANAGEMENT OF ADVANCED PROSTATE CANCER--AN INDEPENDENT SATELLITE SYMPOSIUM (ISS) HELD AS AN ---------------------------------------------------------------------------------------------------------------- \1\ Applicant names are provided by the requestor. If applicants apply as a group for a single educational activity; all applicants may be not be identified above. The Company funds other educational activities (including fellowships and non-physician and patient education); all of which do not appear on this report, but appear on other reports on this site. \2\ ``Funding Amount'' is the amount that the Company funded during Q1, 2016 identified above based upon an agreement. Recipients are required to return any unused funds. Information on unused funds returned by the applicant on activities are not reported. ``Funding Amount'' does not include funds that may have been provided by other affiliated Sanofi Company Entities (e.g., Sanofi Pasteur). \3\ Collaboration (Shared) Funding--is the full amount of a grant funded under an agreement with Regeneron, some or all of which may be shared between the collaborating entities. Independent Medical Education Grants 1st Apr 2016-30th Jun 2016 Sanofi US and its affiliate Genzyme Corporation are committed to supporting independent medical education activities in therapeutic areas in which the Company is involved, for healthcare professionals, patients, and consumers to improve patient care and health outcomes in therapeutic areas in which the Company is engaged. Sanofi US and Genzyme Corporation are part of the Sanofi Group, a global pharmaceutical company. ---------------------------------------------------------------------------------------------------------------- Funding Amount Recipient Name(s) \1\ Activity Title ($) \2\ ---------------------------------------------------------------------------------------------------------------- Academic CME, LLC STRATEGIES FOR IMPROVING OUTCOMES IN PATIENTS WITH 20,000 MULTIPLE SCLEROSIS AKH Inc., Advancing Knowledge and NOVEL MECHANISMS AND ADVANCING THERAPEUTIC PARADIGMS 350,000 Healthcare C-MEducation Resources, FOR OPTIMIZING REAL WORLD MANAGEMENT OF Collaboration \3\ LLC HYPERCHOLESTEROLEMIA: APPLYING LDLTARGETED THERAPIES FOR CV RISK REDUCTION TO THE FRONT LINES OF CARDIOVASCULAR, DIABETES, AND INTERNAL MEDICINE PRACTICE AKH Inc Advancing Knowledge and NAVIGATING THE COMPLEX MAZE OF LDL-LOWERING THERAPIES: 378,700 Healthcare C-MEducation Resources, A REAL WORLD ROADMAP FOR THE CARDIOVASCULAR Collaboration \3\ LLC SPECIALIST American Academy of Physician AAPA CONFERENCE 2016--ENDOCRINOLOGY TRACK 12,500 Assistants American Academy of Physician AAPA CONFERENCE 2016--NEPHROLOGY TRACK 6,000 Assistants American Academy of Physician AAPA CONFERENCE 2016--ORTHOPAEDICS TRACK 7,500 Assistants American Association of Clinical AACE 25TH ANNUAL MEETING AND CLINICAL CONGRESS-- 5,0000 Endocrinologists DIABETES SESSIONS American Association of Clinical CALIFORNIA CHAPTER OF THE AMERICAN ASSOCIATION OF 20,000 Endocrinologists CLINICAL ENDOCRINOLOGISTS PRESENTS: HOT TOPICS IN DIABETES AND ENDOCRINOLOGY FOR PRIMARY CARE 2016 American Association of Diabetes AADE 2016: DOES THE SHOE FIT? MATCHING THE RIGHT 321,194 Educators Institute for Medical and INSULIN COMBINATION TO INDIVIDUAL PATIENTS WITH T2DM Nursing Education American Association of Nurse SECONDARY PREVENTION OF ASCVD: NOVEL THERAPIES TO 75,000 Practitioners (AANP) Medical IMPROVE OUTCOMES IN PATIENTS WITH Collaboration \3\ Communications Media, Inc. HYPERCHOLESTEROLEMIA American College of Allergy, Asthma & EAC 2016 - UPDATE IN ALLERGY, ASTHMA & IMMUNOLOGY 10,000 Immunology Eastern Allergy Collaboration \3\ Conference American Diabetes Association DIABETES IS PRIMARY 133,595 American Diabetes Association 31ST ANNUAL CLINICAL CONFERENCE ON DIABETES 32,000 American Society of Gene Therapy ASGCT 19TH ANNUAL MEETING 26,000 American Society of Health-System THE CHANGING LANDSCAPE OF HYPERCHOLESTEROLEMIA: THE 117,215 Pharmacists EMERGING ROLE OF NON-STATIN THERAPIES Collaboration \3\ American Thoracic Society ATS 2016 INTERNATIONAL CONFERENCE--SELECTED SESSIONS 20,178 IN ASTHMA Collaboration \3\ Baylor University Medical Center dba UPDATE ON GLP-1 RECEPTOR AGONISTS IN THE MANAGEMENT OF 20,000 A. Webb Roberts Center MedNet, LLC TYPE 2 DIABETES MELLITUS Carolinas Healthcare System/Charlotte 30TH ANNUAL MEETING OF THE GLOMERULAR DISEASE 3,000 AHEC COLLABORATIVE NETWORK Children's Hospital Corporation BOSTON CHILDREN'S HOSPITAL, DIVISION OF NEPHROLOGY 5,500 WEEKLY SEMINAR SERIES Consortium of Multiple Sclerosis 2016 SCIENCE OF MS MANAGEMENT 69,225 Centers Nurse Practitioner Alternatives Foundation of the Consortium of MS 2016 MS MENTORSHIP FORUM 25,000 Centers Horizon CME, Inc. GLP-1 RECEPTOR AGONISTS: AN ALTERNATIVE TO PRANDIAL 265,190 INSULIN Horizon CME, Inc. ACHIEVING LDL GOALS IN PATIENTS WITH 187,395 HYPERCHOLESTEROLEMIA: APPLYING PCSK9 INHIBITORS IN Collaboration \3\ PRACTICE Horizon CME, Inc. CURRENT THERAPIES FOR PROSTATE CANCER 24,000 Johns Hopkins University Medical PATIENT-CENTERED CARE IN ADVANCED PROSTATE CANCER 60,000 Communications Media, Inc. Johns Hopkins University Medical MULTIPLE SCLEROSIS IN THE AGE OF ENHANCED THERAPEUTIC 100,000 Logix, LLC OPTIONS Johns Hopkins University Medscape, REAL-LIFE SCENARIOS: SIMULATION IN MCRPC 50,000 LLC Medical Education Resources Tarsus PATIENT-FOCUSED LDL-C MANAGEMENT AND RISK REDUCTION IN 200,000 Cardio Inc. dba Cardiometabolic CLINICAL PRACTICE: THE UTILITY OF PCSK9 INHIBITORS Collaboration \3\ Health Congress Med-IQ, LLC RECENT UPDATES IN CKD-MBD: MERGING SCIENCE AND PATIENT- 84,883 CENTERED CARE Med-IQ, LLC Taking Control of Your PRACTICAL STRATEGIES FOR ADVANCING INSULIN THERAPY: 995,246.5 Diabetes FROM TIMELY INITIATION AND APPROPRIATE TITRATION OF BASAL INSULIN TO ADDRESSING POST PRANDIAL GLUCOSE CONTROL Medscape, LLC KEY CONCEPTS IN CKD-MBD: ESSENTIALS FOR IMPROVING 199,500 OUTCOMES Medscape, LLC ADVANCES IN BASAL INSULIN 829,075 Medscape, LLC CME-TV: INDIVIDUALIZING T2D INSULIN THERAPY UTILZIING 816,000 COMPLIMENTARY MECHANISMS OF ACTION Medscape, LLC CASE CONSIDERATIONS: HOW TO REDUCE CV RISK IN 225,100 DYSLIPIDEMIA? Collaboration \3\ Medscape, LLC 2016 UPDATE: CLINICAL ADVANCEMENTS IN MODERATE TO 640,000 SEVERE ATOPIC DERMATITIS Collaboration \3\ Medscape, LLC WHAT DO WE KNOW ABOUT LDL-C?: A 2016 UPDATE 242,190 Collaboration\3\ Medscape, LLC A PATIENT JOURNEY THROUGH STATIN INTOLERANCE: WHAT 249,215 HAVE WE LEARNED? Collaboration \3\ Medscape, LLC AN ENDOCRINOLOGY CLINIC IN DYSLIPIDEMIA: SOLVING 237,915 CHALLENGING CASES Collaboration \3\ Medscape, LLC RHEUMATOID ARTHRITIS: FOUNDATIONS IN PATHOPHYSIOLOGY, 249,825 TARGETS, AND TREATMENT Collaboration \3\ Medscape, LLC WATERSHEDS IN RHEUMATOID ARTHRITIS: A CONCISE GUIDE TO 99,500 MAJOR CONFERENCES IN 2016 Collaboration \3\ Michigan State Medical Society DIABETES AND LIPID UPDATES 5,000 MidEastern Chapter of the Society of 46TH ANNUAL SPRING MEETING AND EXHIBITION OF THE 7,500 Nuclear Medicine MIDEASTERN CHAPTER OF THE SOCIETY OF NUCLEAR MEDICINE AND MOLECULAR IMAGING Missouri Academy of Physician DIABETES UPDATE FOR THE PRIMARY CARE PROVIDER 5,000 Assistants Montefiore Medical Center PlatformQ EVOLVING TREATMENT PARADIGMS IN METASTATIC CASTRATION- 75,000 Health Education, LLC RESISTANT PROSTATE CANCER National Association of Managed Care BEST PRACTICES IN THE TREATMENT AND MANAGEMENT OF 57,000 Physicians, Inc. RELAPSING MULTIPLE SCLEROSIS National Association of Managed Care ADVANCES IN LDL-C REDUCTION: A STRATEGIC LOOK AT THE 25,000 Physicians, Inc. EFFECTIVENESS OF PCSK9 INHIBITORS Collaboration \3\ National Comprehensive Cancer NCCN 2016 ONCOLOGY CASE MANAGER AND MEDICAL DIRECTOR 25,000 Network, Inc. PROGRAM National Comprehensive Cancer 2016-2017 MONTHLY ONCOLOGY TUMOR BOARDS: A 25,000 Network, Inc. MULTIDISCIPLINARY APPROACH TO INDIVIDUALIZED PATIENT CARE National Jewish Health EVALUATION AND TREATMENT OF SEVERE ASTHMA: THE ROLE OF 94,011.5 BIOLOGIC AND DIRECTED THERAPIES Collaboration \3\ National Jewish Health Prova ATOPIC DERMATITIS: DEFINING ITS PATHOGENESIS, 224,850 Education, Inc. TARGETING ITS TREATMENT Collaboration \3\ National Kidney Foundation, Inc. PATHOGENESIS AND MANAGEMENT OF FABRY DISEASE 166,485 National MS Society Greater New NEW HAMPSHIRE LIVING WELL WITH MS CONFERENCE 1,500 England Chapter National Lipid Association TRANSLATION OF THE LDL RECEPTOR: A NATIONAL LIPID 125,000 ASSOCIATION CORE CURRICULUM INTENSIVE PROGRAM Collaboration \3\ New Jersey Academy of Family MANAGING T2DM IN SPECIAL POPULATIONS 6,000 Physicians North American Center for Continuing GRAND ROUNDS IN CARDIOLOGY: PCSK9 INHIBITORS WITHIN 499,838 Medical Education, LLC THE TARGETED TREATMENT APPROACH TO Collaboration \3\ HYPERCHOLESTEROLEMIA Nurse Practitioner Alternatives IMPROVING CARE IN MULTIPLE SCLEROSIS: A NURSING 100,000 International Organization of PERSPECTIVE Multiple Sclerosis Nurses Nurse Practitioner Alternatives MULTIPLE SCLEROSIS 2016: WHAT NURSES NEED TO KNOW 57,900 International Organization of Multiple Sclerosis Nurses Nurse Practitioner Alternatives 2016 MS COUNSELING POINTS:HIGHLIGHTING THE ROLE OF 35,625 International Organization of NURSES IN MULTIDISCIPLINARY MANAGEMENT OF MS Multiple Sclerosis Nurses Oakstone Publishing, LLC PeerVoice ADVANCEMENTS IN CARE FOR PATIENTS WITH 29,725 America Limited HYPERCHOLESTEROLEMIA AND RESIDUAL CV RISK: EMERGING Collaboration \3\ DATA, EVOLVING STRATEGIES Oregon Health & Science University ON THE HORIZON: UPDATES IN MULTIPLE SCLEROSIS 9,930 Foundation Penn State University i3 Health GUIDELINE UPDATES AND EVOLVING CLINICAL PARADIGMS IN 23,500 DIFFERENTIATED THYROID CANCER Penn State University PeerView PEERVIEW SELECT-A-SCENARIO LIVE: TRANSFORMING PROSTATE 120,510 Institute for Medical Education, CANCER CARE IN A RAPIDLY EVOLVING TREATMENT LANDSCAPE Inc. Penn State University PeerView PEERVIEW SELECT-A-SCENARIO LIVE: ``CRITICAL 150,000 Institute for Medical Education, DISCUSSIONS IN PROSTATE CANCER: HOW TO SELECT AND Inc. SEQUENCE THERAPIES THROUGHOUT THE DISEASE CONTINUUM'' Pharmacy Times Office of Continuing ACHIEVING GLYCEMIC CONTROL: PROMOTING PATIENT SELF- 57,000 Professional Education MONITORING AND EXPLORING INNOVATIVE TREATMENT STRATEGIES IN THE CONVENIENT CARE SETTING Pharmacy Times Office of Continuing MANAGING HYPERLIPIDEMIA: A NEW CHARGE FOR SPECIALTY 32,000 Professional Education PHARMACY WITH THE ADVENT OF PCSK9 INHIBITORS Collaboration \3\ Pharmacy Times Office of Continuing OPTIMIZING TREATMENT REGIMENS FOR MS: THE PHARMACIST?S 35,000 Professional Education ROLE IN ADVANCING PATIENT CARE Pharmacy Times Office of Continuing MANAGING ATOPIC DERMATITIS: A PHARMACIST'S OPPORTUNITY 86,450 Professional Education TO INTERVENE Collaboration \3\ Physicians' Education Resource, LLC CANCER SUMMARIES AND COMMENTARIE: UPDATE FROM CHICAGO: 40,000 ADVANCES IN THE TREATMENT OF GENITOURINARY CANCERS Pna Centers For Neurological Research RRNMF COURSE ON POMPE'S DISEASE RECOGNITION AND 25,000 THERAPY Postgraduate Healthcare Education, THE CHANGING LANDSCAPE IN THE TREATMENT OF RHEUMATOID 52,500 LLC ARTHRITIS: AN UPDATE FOR PHARMACISTS Collaboration \3\ Postgraduate Institute for Medicine C- IQ&A INTERACTIVE DIABETES INTELLIGENCE ZONE: GLYCEMIC 191,000 MEducation Resources, LLC REGULATION THROUGH COMBINATION THERAPY--FOCUS ON SAFETY, CONVENIENCE, METABOLIC EFFECTS, HA1C CONTROL, AND EFFICACY OF COMBINATION BASAL INSULIN-GLP-1 RA REGIMENS FOR FPG AND PPG CONTROL Postgraduate Institute for Medicine WHY AREN'T THEY TAKING THEIR MEDS? PATIENT-CENTERED 33,000 Enquiring Minds LLC APPROACHES TO NON-ADHERENCE IN MS Primary Care Education Consortium REMOVING THE COMPLEXITY AND CONCERNS OF INSULIN 78,595 MANAGEMENT IN TYPE 2 DIABETES, 4-HOUR WORKSHOPS TO BE HELD DURING THE METABOLIC AND ENDOCRINE DISEASE SUMMITS 2016 PRIME Education Inc (PRIME) PRACTICAL SKILLS IN MEDICATION MANAGEMENT WITH NEWER 415,000 CHOLESTEROL THERAPIES: CAN WE ACHIEVE PATIENT AND Collaboration \3\ MANAGED CARE HOMEOSTASIS? PRIME Education Inc (PRIME) GME-CME ADVANCED PRACTICE SEMINAR IN MULTIPLE 150,329 SCLEROSIS: FOCUSED TRAINING FOR EFFECTIVE INDIVIDUALIZED TREATMENT DECISION-MAKING PRIME Education Inc (PRIME) RHEUMATOLOGY HOUSE CALLS--ENGAGING PATIENTS AND 172,845 PROVIDERS IN RHEUMATOID ARTHRITIS COLLABORATIVE Collaboration \3\ LEARNING PRIME Education Inc (PRIME) NEW TARGETS IN THE THERAPEUTIC LANDSCAPE FOR ADULTS 291,095 WITH ATOPIC DERMATITIS Collaboration \3\ Pri-Med Institute, LLC (d/b/a pmiCME) OSTEOARTHRITIS OF THE KNEE: A MULTI-MODAL APPROACH TO 160,000 PAIN MANAGEMENT Pri-Med Institute, LLC (d/b/a pmiCME) HOW LOW DO YOU GO? CLINICAL UPDATES IN LOW-DENSITY 490,479 LIPOPROTEINCHOLESTEROL MANAGEMENT Collaboration \3\ Purdue University Focus Medical 2016 ARTHROS CITY ROUNDS SERIES 10,000 Communications, LLC Collaboration \3\ Research Foundation of SUNY MEASURING QUALITY OF LIFE (QOL) IN ESRD 5,000 Research To Practice YEAR IN REVIEW--A FOUR-PART MULTI-TUMOR REGIONAL CME 60,000 SYMPOSIA SERIES FOCUSED ON THE APPLICATION OF EMERGING RESEARCH INFORMATION TO THE CARE OF PATIENTS WITH COMMON CANCERS: GENITOURINARY CANCERS MODULE San Francisco Neurological Society CALIFORNIA NEUROLOGY SOCIETY - UPDATES IN NEUROLOGY 3,000 Association of California 2016 Neurologists Foundation Scripps Health ANNUAL NEW APPROACHES TO OPTIMIZE REAL-WORLD DIABETES 50,000 CARE: SPRING CONFERENCE Society for Urologic Nurses and COMPETENCE IN ADVANCED PROSTATE CANCER REGIONAL ONS 30,000 Associates (SUNA) CHAPTER NURSING FORUMS. DEVELOPING STRATEGIES FOR SEQUENCING AND COMBINING THERAPIES: NURSING CONSIDERATIONS FOR IMPLEMENTING A TAILORED TREATMENT APPROACH Society of Nuclear Medicine 61ST ANNUAL MEETING OF THE SOUTHWESTERN CHAPTER, SNMMI 2,000 Southwestern Chapter of the Society of Nuclear Medicine Swedish Medical Center Foundation SIXTH ANNUAL INTENSIVE UPDATE IN NEUROLOGY 3,000 Texas A&M University System Health 12TH ANNUAL DIABETES CONFERENCE: 'DIABETES HEAD TO 10,000 Science Center Coastal Be TOE' The Endocrine Society ENDO 2016 GENYZME THYROID SESSIONS 100,000 The Omnia-Prova Education MANAGEMENT OF RA: GLOBAL OUTLOOK AND LATIN AMERICAN 311,067 Collaborative, Inc. Prova Education, IMPLICATIONS Collaboration \3\ Inc. Trustees of Boston University KEYS TO ACHIEVING OPTIMAL GLUCOSE CONTROL: EARLY 375,000 Continuing Education Alliance, LLC INSULIN INITIATION AND CONTROL OF POSTPRANDIAL GLUCOSE Trustees of Boston University IMPLEMENTING NEW THERAPIES FOR REFRACTORY 350,000 Continuing Education Alliance, LLC DYSLIPIDEMIA: PRACTICAL CONSIDERATIONS FOR CLINICAL Collaboration \3\ PRACTICE Ultimate Medical Academy, LLC dba IMPROVING OUTCOMES IN SEVERE ASTHMA: A NEW ERA IN 185,333 Global Education Group Integritas PRECISION MEDICINE Collaboration \3\ Communications, LLC UMA MLG, LLC COMPREHENSIVE DYSLIPIDEMIA MANAGEMENT: A VIRTUAL 249,825 REALITY TOUR BEYOND STATIN MONOTHERAPY Collaboration\3\ University of Chicago Intelligent INSIDE DYSLIPIDEMIA MANAGEMENT: IMPROVING RISK 285,734 Medical Decisions, Inc. ASSESSMENT, REFERRALS AND LIPID GOAL ATTAINMENT FOR Collaboration \3\ HIGH-RISK CV PATIENTS INSPIRING SYSTEM IMPROVEMENT WITH DATA-DRIVEN EDUCATION University of Cincinnati Advances in MAUIDERM NP+PA SUMMER 2016 25,000 Cosmetic and Medical Dermatology Collaboration \3\ University of Kansas Endowment NEUROMUSCULAR REVIEW COURSE SERIES 2016 15,000 Association University of Massachusetts Medical PIVOTAL TREATMENT ADVANCES IN BIOLOGIC THERAPY FOR 376,000 School C-MEducation Resources, LLC ATOPIC DERMATITIS (AD): FOCUS ON THE Collaboration \3\ IMMUNOPATHOBIOLOGY OF AD AND ROLE OF EVOLVING BIOLOGIC THERAPIES FOR OPTIMIZING OUTCOMES IN PATIENTS WITH MODERATE-TO-SEVERE AND TREATMENT- RESISTANT AD University of Rochester Society of 2016 SOCIETY FOR INVESTIGATIVE DERMATOLOGY ANNUAL 50,000 Investigative Dermatology MEETING Collaboration \3\ University of Southern California VAN DER MEULEN SYMPOSIUM: MULTIPLE SCLEROSIS UPDATE 20,000 University of Tennessee Advanced ONCOLOGY PHARMACY CONSULTS: UPDATES ON THE MANAGEMENT 45,000 Studies in Medicine OF PROSTATE CANCER University of Texas Health Science AMERICAN SOCIETY OF CLINICAL ONCOLOGY (ASCO) 2016 3,500 Center at San Antonio REVIEW University of Vermont and State NEW ENGLAND THYROID CONFERENCE 10,000 Agricultural College USF Health Professions Conferencing 13TH ANNUAL ROCKY MOUNTAIN METABOLIC SYNDROME 5,000 Corporation CEConsultants, LLC SYMPOSIUM Wellmont Health System 14TH ANNUAL DIABETES SYMPOSIUM 4,000 Yale University INAUGURAL 1-95 INFILTRATIVE CARDIOMYOPATHY CONFERENCE 5,000 ---------------------------------------------------------------------------------------------------------------- \1\ Applicant names are provided by the requestor. If applicants apply as a group for a single educational activity; all applicants may be not be identified above. The Company funds other educational activities (including fellowships and non-physician and patient education); all of which do not appear on this report, but appear on other reports on this site. \2\ ``Funding Amount'' is the amount that the Company funded during Q2, 2016 identified above based upon an agreement. Recipients are required to return any unused funds. Information on unused funds returned by the applicant on activities are not reported. ``Funding Amount'' does not include funds that may have been provided by other affiliated Sanofi Company Entities (e.g., Sanofi Pasteur). \3\ Collaboration (Shared) Funding--is the full amount of a grant funded under an agreement with Regeneron, some or all of which may be shared between the collaborating entities. Independent Medical Education Grants 1st July 2016-30th Sep 2016 Sanofi US and its affiliate Genzyme Corporation are committed to supporting independent medical education activities in therapeutic areas in which the Company is involved, for healthcare professionals, patients, and consumers to improve patient care and health outcomes in therapeutic areas in which the Company is engaged. Sanofi US and Genzyme Corporation are part of the Sanofi Group, a global pharmaceutical company. ---------------------------------------------------------------------------------------------------------------- Funding Amount Recipient Name(s) \1\ Activity Title ($) \2\ ---------------------------------------------------------------------------------------------------------------- American Association of Clinical ORR-AACE 18TH ANNUAL MEETING 5,000 Endocrinologists American Association of Clinical MID ATLANTIC-AACE 14TH ANNUAL MEETING 2,500 Endocrinologists American Association of Clinical TEXAS-AACE ANNUAL MEETING & TEXAS ENDOCRINE SURGICAL 5,000 Endocrinologists SYMPOSIUM American Association of Clinical NEVADA AACE ENDOCRINOLOGY FOR THE NON ENDOCRINOLOGISTS 5,000 Endocrinologists AND ANNUAL MEETING American Association of Clinical NEVADA-AACE ENDOCRINOLOGY FOR THE NON ENDOCRINOLOGISTS 7,500 Endocrinologists AND ANNUAL MEETING American Association of Nurse BEST PRACTICES IN ACHIEVING OPTIMAL A1C TARGETS AND 141,980 Practitioners (AANP) POST PRANDIAL GLYCEMIC CONTROL American Diabetes Association 14TH ANNUAL PROFESSIONAL EDUCATION SYMPOSIUM, AN 10,000 AFTERNOON WITH DIABETES EXPERTS: DIABETES DISTRESS, PHYSICAL ACTIVITY, MEDICATIONS, AND UPDATES TO THE STANDARDS American Health Resources, Inc. EXAMINING NEW OPTIONS IN THE MANAGEMENT OF INSULIN 4,600 RESISTANT TYPE 2 DIABETES: A FOCUS ON BASAL INSULIN THERAPY American Society for Blood and Marrow 2017 ASBMT/SANOFI NEW INVESTIGATOR AWARD 65,000 Transplantation Antidote Education Company MANAGING DIABETES IN OLDER POPULATIONS 50,000 California Academy of Physician MANAGEMENT OF OSTEOARTHRITIS IN THE PRIMARY SETTING 4,000 Assistants California Academy of Physician 2016 ANNUAL MEETING OF THE CALIFORNIA ACADEMY OF 4,000 Assistants PHYSICIAN ASSISTANTS (CAPA): UPDATES IN TYPE 2 DIABETES CARE Cardiovascular Research Foundation BEST MANAGEMENT FOR COMPLEX PATIENTS WITH COMPLEX 58,100 DISEASE: THE NEXT FRONTIER BEYOND REVASCULARIZATION Consortium of Multiple Sclerosis 2016 CMSC ANNUAL MEETING SCIENTIFIC PROGRAM 25,000 Centers Nurse Practitioner Alternatives Consortium of Multiple Sclerosis MS AT THE CUTTING EDGE: A 5-PART WEBINAR SERIES 56,700 Centers Nurse Practitioner Alternatives Dignity Health MandatoryCE LLC 5TH ANNUAL ARIZONA DIABETES SYMPOSIUM 50,000 Dignity Health MandatoryCE LLC 2016 ARKANSAS DIABETES SYMPOSIUM: FOCUS ON PREVENTION, 35,000 CURRENT TREATMENTS, AND COMORBIDITIES Elsevier Office of Continuing Medical ECTRIMS 2016: OPTIMALLY MANAGING PATIENTS WITH 85,000 Education Academic CME, LLC MULTIPLE SCLEROSIS THROUGH INDIVIDUALIZED TREATMENT OPTIONS Emory University 9TH WORLD CONGRESS ON PREVENTION OF DIABETES AND ITS 50,000 COMPLICATIONS Florida Academy of Physician EVALUATING KIDNEY DISEASE: KIDNEY KASES 5,000 Assistants Florida Academy of Physician JOINT INJECTIONS 5,500 Assistants Foundation for Orthopaedic Research ORTHOPAEDICS FOR THE PRIMARY CARE PRACTITIONER & 5,000 and Education, Inc. REHABILITATION THERAPIST Horizon CME, Inc. GLP-1 RECEPTOR AGONIST AND BASAL INSULIN: AN EMERGING 53,253 STANDARD FOR TYPE DIABETES TREATMENT Horizon CME, Inc. ULTRALONG-ACTING BASAL INSULINS: WHERE DO THEY FIT? 53,253 Integritas Communications, LLC CLINICAL UPDATES IN THE MANAGEMENT OF SEVERE ASTHMA: 5,000 Ultimate Medical Academy, LLC dba NEW STRATEGIES TO INDIVIDUALIZE LONG-TERM CARE Collaboration \3\ Global Education Group LeBonheur Children's Hospital BACK TO SCHOOL DIABETES CONFERENCE 3,828 Medical Education Resources Tarsus COMBINING GLP-1RAS WITH INSULIN TO IMPROVE GLUCOSE 159,650 Cardio Inc. dba Cardiometabolic CONTROL Health Congress Medical Learning Institute, Inc. PEERVIEW VIDEO INSESSION AT AAN 2016, ``STAYING 131,530 PeerView Institute for Medical CURRENT WITH THE LATEST UPDATES ON APPROVED DISEASE- Education, Inc. MODIFYING THERAPIES FOR MULTIPLE SCLEROSIS MANAGEMENT: CLINICAL HIGHLIGHTS FROM VANCOUVER'' Med-IQ, LLC SEQUENCING TREATMENT FOR METASTATIC CASTRATION- 158,565 RESISTANT PROSTATE CANCER: HOW TO MATCH PATIENTS TO THE RIGHT THERAPY Med-IQ, LLC THE EVOLVING THERAPEUTIC LANDSCAPE FOR MODERATE-TO- 88,759 SEVERE ATOPIC DERMATITIS Collaboration \3\ National Association for Continuing POSTPRANDIAL HYPERGLYCEMIA AND GLP-1 RECEPTOR 150,000 Education AGONISTS: EFFECTIVE STRATEGIES TO ACHIEVE GOALS National Association of Managed Care NEW PERSPECTIVES AND EMERGING TREATMENT PARADIGMS IN 57,000 Physicians, Inc. THE MANAGEMENT OF RELAPSING MULTIPLE SCLEROSIS National Association of Managed Care CLINICAL ADVANCES IN ATOPIC DERMATITIS: NOVEL 57,000 Physicians, Inc. THERAPIES FOR IMPROVED PATIENT OUTCOMES National Association of Managed Care IMPROVING PATIENT OUTCOMES WITH INDIVIDUALIZED THERAPY 57,000 Physicians, Inc. IN THE MANAGEMENT OF TYPE 2 DIABETES National Kidney Foundation, Inc. 25TH ANNUAL FELLOWS RESEARCH FORUM 3,500 National Kidney Foundation, Inc. CHRONIC KIDNEY DISEASE-MINERAL BONE DISORDER: 149,420 University of Illinois at Chicago IMPLICATIONS FOR CARDIAC OUTCOMES National Medical Association STRATEGIES TO ACHIEVE BETTER CLINICAL OUTCOMES IN TYPE 200,000 2 DIABETES AND ITS THERAPEUTIC COMPLICATIONS Penn State University Antidote 16TH ANNUAL DIABETES SYMPOSIUM 15,000 Education Company Penn State University Medical STRATEGIES FOR IMPROVING OUTCOMES IN PATIENTS WITH MS 15,000 Communications Media, Inc. Pennsylvania Society of Physician NEW TREATMENT OPTIONS IN DIABETES MELLITUS 8,000 Assistants Potomac Center for Medical Education EXPANDING DMD TREATMENT OPTIONS FOR PATIENTS WITH MS 205,000 Rockpointe Corporation Primary Care Network, Inc. PlatformQ THE EVOLUTION OF BASAL INSULINS: ONE SMALL STEP OR A 100,000 Health Education, LLC GIANT LEAP? Projects In Knowledge MedPage Today, NEUROLOGY MASTERY IN MULTIPLE SCLEROSIS 120,000 LLC Regents of the University of 6TH ANNUAL UC IRVINE HEALTH NEUROMUSCULAR COLLOQUIUM 20,000 California Regents of the University of Colorado PRACTICAL WAYS TO ACHIEVE TARGETS IN DIABETES CARE 200,000 Regents, University of California THE 4TH ANNUAL UCLA DIABETES SYMPOSIUM 10,000 Scripps Health ANNUAL NEW APPROACHES TO OPTIMIZE REAL-WORLD DIABETES 70,000 CARE: FALL CONFERENCE AND ENDURING MATERIALS The Board of Trustees of the UA for SPECIAL NEPHROLOGY RESEARCH AND TRAINING CENTER 15,000 the UA at Birmingham SYMPOSIUM--11/9/15 The Medical College of Wisconsin, 2016 ASBMT CLINICAL RESEARCH TRAINING COURSE 25,000 Inc. American Society for Blood and Marrow Transplantation University of California, San Diego-- PROMOTING BEHAVIOR CHANGE IN DIABETES: A SKILL 50,000 Behavioral Diabetes Institute BUILDING PROGRAM FOR HEALTH CARE PROFESSIONALS University of California, San Diego ADDRESSING THE NATURAL HISTORY OF TYPE 2 DIABETES: 142,899 Taking Control of Your Diabetes PRACTICAL APPROACHES TO CONTROLLING FASTING AND POST- PRANDIAL GLUCOSE LEVELS University of Cincinnati Global HE METABOLIC & ENDOCRINE DISEASE SUMMIT (MEDS) 2016 25,000 Academy for Medical Education, LLC T ---------------------------------------------------------------------------------------------------------------- \1\ Applicant names are provided by the requestor. If applicants apply as a group for a single educational activity; all applicants may be not be identified above. The Company funds other educational activities (including fellowships and non-physician and patient education); all of which do not appear on this report, but appear on other reports on this site. \2\ ``Funding Amount'' is the amount that the Company funded during Q3, 2016 identified above based upon an agreement. Recipients are required to return any unused funds. Information on unused funds returned by the applicant on activities are not reported. ``Funding Amount'' does not include funds that may have been provided by other affiliated Sanofi Company Entities (e.g., Sanofi Pasteur). \3\ Collaboration (Shared) Funding--is the full amount of a grant funded under an agreement with Regeneron, some or all of which may be shared between the collaborating entities. Independent Medical Education Grants 1st Oct 2016-31th Dec 2016 Sanofi US and its affiliate Genzyme Corporation are committed to supporting independent medical education activities in therapeutic areas in which the Company is involved, for healthcare professionals, patients, and consumers to improve patient care and health outcomes in therapeutic areas in which the Company is engaged. Sanofi US and Genzyme Corporation are part of the Sanofi Group, a global pharmaceutical company. ---------------------------------------------------------------------------------------------------------------- Funding Amount Recipient Name(s) \1\ Activity Title ($) \2\ ---------------------------------------------------------------------------------------------------------------- American Academy of Pas 2016 ADULT HOSPITAL MEDICINE BOOT CAMP 5,000 American Association of Clinical CALIFORNIA CHAPTER OF THE AMERICAN ASSOCIATION OF 5,000 Endocrinologists CLINICAL ENDOCRINOLOGISTS (CA AACE) 16TH ANNUAL MEETING & SYMPOSIUM American Association of Clinical DIABETES DAY FOR PRIMARY CARE CLINICIANS ADVANCES IN 75,000 Endocrinologists DIABETES CARE American College of Allergy, Asthma & PLENARY SESSION: MODERN THERAPIES FOR ALLERGIC SKIN 35,000 Immunology DISEASES Collaboration \3\ American Health Resources, Inc. NEW COMPLEMENTARY COMBINATION THERAPY FOR DIABETES: 21,800 FIXED DOSE BASAL INSULINS AND GLP-1 RECEPTOR AGONISTS American Nephrology Nurses' IMPROVING PATIENT OUTCOMES IN CKD-MBD: INDIVIDUALIZED 139,250 Association MANAGEMENT AND ENHANCED PATIENT ENGAGEMENT American Society of Nephrology CKD-MBD GUIDELINES: A CRITICAL APPRAISAL OF RECENT 181,790 STUDIES American Society of Transplantation AST FELLOWS SYMPOSIUM ON TRANSPLANTATION (2016) 35,000 American Thyroid Association, Inc. 3RD ANNUAL E. CHESTER RIDGWAY TRAINEE CONFERENCE 25,000 University of Colorado School of Medicine American Thyroid Association, Inc. 86TH ANNUAL MEETING OF THE AMERICAN THYROID 50,000 University of Colorado School of ASSOCIATION Medicine American Urological Association ADVANCEMENTS IN UROLOGY 2017, AN AUA/JUA SYMPOSIUM 15,000 American Urological Association ADVANCED PROSTATE CANCER: MANAGING THE SPECTRUM OF THE 60,000 Education & Research, Inc. DISEASE Annenberg Center for Health Sciences EXPERTPERSPECTIVES: SHIFTING PARADIGMS, EMERGING 224,355 at Eisenhower TREATMENTS IN MODERATE TO SEVERE ATOPIC DERMATITIS Collaboration \3\ Annenberg Center for Health Sciences DEVELOPMENT OF SPANISH LANGUAGE VERSION OF: ANIMATED 75,000 at Eisenhower Postgraduate Institute MULTIPLE SCLEROSIS (MS) PATIENT AN ANIMATED PATIENTS for Medicine Prime Medic GUIDE TO MS/ANIMADAS DE ESCLEROSIS MULTIPLE (EM) PACIENTE GUIA DEL PACIENTES ANIMADA A EM Augusta University NEUROLOGY FOR THE NON-NEUROLOGIST 5,000 AXIS Medical Education, Inc. AUTOLOGOUS HEMATOPOIETIC STEM CELL TRANSPLANTATION AND 74,580 MOBILIZATION IN MULTIPLE MYELOMA: CURRENT DEBATE AND DEVELOPMENTS Baylor Scott & White Health Baylor 3RD ANNUAL SYMPOSIUM ON INDIVIDUALIZED NOVEL DISEASE- 40,000 University Medical Center dba A. MODIFYING TREATMENT OPTIONS FOR MULTIPLE SCLEROSIS Webb Roberts Center MedNet, LLC Baylor Scott & White Health MedNet EMERGING BIOLOGICAL THERAPIES FOR ATOPIC DERMATITIS IN 35,000 CHILDREN AND ADULTS Collaboration \3\ California Optometric Association FABRY DISEASE--OPHTHALMIC MANIFESTATIONS AND RECENT 9,650 ADVANCES Cleveland Clinic Educational MULTIPLE SCLEROSIS CASE-BASED ONLINE MONOGRAPH 25,000 Foundation Clinical Care Options, LLC NEW DIRECTIONS IN GU CANCERS: HIGHLIGHTS FROM THE 2017 25,000 Postgraduate Institute for Medicine GENITOURINARY CANCERS SYMPOSIUM C-MEducation Resources, LLC AKH Inc NEW FRONTIERS AND PIVOTAL CLINICAL ADVANCES IN 297,000 Advancing Knowledge and Healthcare PATHOIMMUNOBIOLOGY OF ATOPIC DERMATITIS: THE Collaboration \3\ TRANSLATIONAL PATH IN ATOPIC DERMATITIS AND IMPLICATIONS FOR DERMATOLOGY PRACTICE Consortium of Multiple Sclerosis ADDRESSING COMORBIDITIES IN THE DIAGNOSIS AND 85,000 Centers Nurse Practitioner MANAGEMENT OF PATIENTS WITH MULTIPLE SCLEROSIS: A Alternatives RESOURCE GUIDE FOR CLINICIANS Consortium of Multiple Sclerosis CLINICAL CONSULT: CASES AND COMPREHENSIVE CARE IN MS 115,200 Centers Nurse Practitioner Alternatives Consortium of Multiple Sclerosis MONITORING AND FOLLOW-UP IN MULTIPLE SCLEROSIS 60,725 Centers Nurse Practitioner COMPREHENSIVE CARE Alternatives Continuing Education Alliance, LLC TARGETED THERAPIES IN MODERATE TO SEVERE ATOPIC 92,550 Board of Regents for University of DERMATITIS: EMERGING OPTIONS Collaboration \3\ Nebraska Creative Educational Concepts, Inc. ADVANCED PROSTATE CANCER: SEARCHING FOR OPTIMAL 15,000 THERAPY SEQUENCE AND ASSESSING EMERGING TREATMENT OPTIONS Delaware Academy of Physician MULTIPLE SCLEROSIS 2,200 Assistants Inc. Elsevier Office of Continuing Medical CLINICAL ADVANCES IN RHEUMATOID ARTHRITIS: A FOCUS ON 350,000 Education Advanced Studies in IMPROVING PATIENT OUTCOMES Medicine Elsevier Office of Continuing Medical SPOTLIGHT ON FABRY DISEASE: DIAGNOSIS, GENOTYPE- 200,000 Education Excerpta Medica PHENOTYPE CORRELATION, AND MULTIDISCIPLINARY PATIENT CARE Elsevier Office of Continuing Medical ESMO2016: A THERAPEUTIC UPDATE ON THE MANAGEMENT OF 90,000 Education Excerpta Medica BV PATIENTS WITH PROSTATE CANCER Excel Continuing Education MULTIPLE SCLEROSIS: MANAGING THE DISEASE, ITS SYMPTOMS 7,000 AND QUALITY OF LIFE (PART OF THE SOUTH FLORIDA NEUROLOGY SYMPOSIUM: IMPROVING PATIENT OUTCOMES) Excel Continuing Education NEW DIRECTIONS IN THE MANAGEMENT OF POMPE DISEASE 64,120 Florida Academy of Physician MULTIPLE SCLEROSIS 5,000 Assistants Inc. Foundation of the Consortium of MS 2016-2017 ROBERT LISAK, MD MEDICAL STUDENT RESEARCH 8,000 Centers SCHOLARSHIP Global Academy for Medical Education SKIN DISEASE EDUCATION FOUNDATION'S 17TH ANNUAL LAS 25,000 Postgraduate Institute for Medicine VEGAS DERMATOLOGY SEMINAR FEATURING THE 13TH ANNUAL Collaboration \3\ Rutgers, the State University PSORIASIS FORUM Global Academy for Medical Education 16TH ANNUAL CARIBBEAN DERMATOLOGY SYMPOSIUM 20,000 Rutgers Biomedical and Health Collaboration \3\ Sciences Global Academy for Medical Education SKIN DISEASE EDUCATION FOUNDATION'S 41ST ANNUAL HAWAII 50,000 University of Louisville Research DERMATOLOGY SEMINAR Collaboration \3\ Foundation Haymarket Medical Education BASAL INSULIN PLUS GLP-1 RAS: THERAPEUTIC SYNERGIES TO 146,788 OPTIMIZE PATIENT OUTCOMES: 4 VIDEO ``HOUSE CALLS'' DISCUSSIONS AMONG EXPERTS Illinois Academy of Physician JOINT INJECTABLES 4,000 Assistants Illinois Academy of Physician CHRONIC KIDNEY DISEASE 5,000 Assistants Indiana Academy of Physician ``WHAT IS CHRONIC KIDNEY DISEASE (CKD) AND END STAGE 6,500 Assistants RENAL DISEASE (ESRD)?'' Indiana Neurological Society Indiana DEMYELINATING DISEASES: WHAT TO DO WHEN THE INSULATION 5,000 State Medical Association BEGINS TO FRAY Integritas Communications Global LOOKING BENEATH THE SURFACE IN ATOPIC DERMATITIS: 361,807 Education Group TARGETING IMMUNE DYSREGULATION AND DELIVERING Collaboration \3\ COMPREHENSIVE CARE Integritas Communications, LLC UMA ATOPIC DERMATITIS: NEW PERSPECTIVES ON MANAGING A 267,480 Education, Inc. dba Global Education CHRONIC INFLAMMATORY DISEASE Collaboration \3\ Group Integritas Communications, LLC UMA CLINICAL ADVANCES IN ATOPIC DERMATITIS: EXPERT 202,218 Education, Inc. dba Global Education INSIGHTS INTO NEW AND EMERGING THERAPIES Collaboration \3\ Group Integritas Communications, LLC UMA CLINICAL UPDATES IN RHEUMATOID ARTHRITIS: NEW 249,900 Education, Inc. dba Global Education STRATEGIES TO TARGET REMISSION AND INDIVIDUALIZE Collaboration \3\ Group COMPREHENSIVE CARE International Eczema Council PSORIASIS AND ATOPIC DERMATITIS: TWO DISEASES OR ONE 100,000 International Psoriasis Council SPECTRUM? Collaboration \3\ International Organization of MS NP CONNECTIONS: THE ROLE OF THE NURSE PRACTITIONER IN 75,000 Nurses Nurse Practitioner MULTIPLE SCLEROSIS CARE Alternatives Kentucky Academy of Physician JOINT INJECTION WORKSHOP 5,000 Assistants Medical Learning Institute Inc. PVI PEERVIEW LIVE AT CMSC 2017, GUIDING PATIENTS THROUGH 345,810 Peerview Institute for Medical THE RISKS AND BENEFITS OF DISEASE-MODIFYING THERAPY: Education Inc. PATIENT STORIES OF SHARED DECISION-MAKING THROUGHOUT THE COURSE OF MULTIPLE SCLEROSIS Medical Learning Institute Inc. PVI PEERVIEW LIVE AT ACMG 2017 STRENGTHENING THE GENETICS- 219,430 Peerview Institute for Medical HEMATOLOGY PARTNERSHIP TO SHORTEN THE PATH TO Education Inc. DIAGNOSIS & TREATMENT OF GAUCHER DISEASE TYPE 1: A PATIENT STORY Medical Learning Institute Inc. PVI, PEERVIEW VIDEO INPLAY NOVEL OPTIONS AND PATIENT 169,480 PeerView for Medical Education Inc. PERSPECTIVES IN RHEUMATOID ARTHRITIS: INDIVIDUALIZING Collaboration \3\ CARE FOR THERAPEUTIC SUCCESS Medical Learning Institute Inc. PVI, PEERVIEW VIDEO INREVIEW: ASSESSING THE COMPARATIVE 60,000 PeerView Institute for Medical EFFECTIVENESS OF DISEASE-MODIFYING THERAPIES: WHAT Education CAN BE LEARNED FROM HEAD-TO-HEAD CLINICAL TRIALS AND RECENT NUMBER-NEEDED-TO-TREAT ANALYSES? Medical Learning Institute, Inc. PEERVIEW IN REVIEW, ``DELAYING DISABILITY PROGRESSION 106,800 PeerView Institute for Medical IN THE MULTIPLE SCLEROSIS PATIENT: WHAT CAN WE LEARN Education, Inc. FROM AVAILABLE DATA ON APPROVED DISEASE-MODIFYING THERAPY?'' Medical Learning Institute, Inc. PEERVIEW TALKS: HIGHLY EFFECTIVE DISEASE-MODIFYING 65,000 PeerView Institute for Medical THERAPIES FOR MULTIPLE SCLEROSIS: WHEN AND IN WHOM Education, Inc. SHOULD THEY BE USED? Medical Learning Institute, Inc. NEW DEVELOPMENTS IN THE TREATMENT OF ATOPIC 156,480 PeerView Institute for Medical DERMATITIS: CLINICAL HIGHLIGHTS FROM VIENNA Collaboration \3\ Education, Inc. Med-IQ, LLC DIFFERENTIATING GAUCHER DISEASE FROM OTHER HEMATOLOGIC 290,043 CONDITIONS: EVERY DAY COUNTS Med-IQ, LLC LYSOSOMAL STORAGE DISEASES: NEWBORN SCREENING UPDATES 261,483 AND IMPLICATIONS FOR LONG-TERM CARE Med-IQ, LLC FABRY DISEASE : WHEN TO TREAT 100,000 Michigan State Medical Society CARING FOR PATIENTS WITH A FOCUS ON THE KIDNEYS 5,000 MS Views And News Inc. 2016 NEUROLOGICAL ASPECTS OF MS AND BEYOND--SYMPOSIUM 17,500 MSWorld Inc. 2016 MSWORLD-HOSTED TALKS SERIES 35,000 National Association of Managed Care NEW HORIZONS IN THE TREATMENT AND MANAGEMENT OF 70,000 Physicians, Inc. MULTIPLE SCLEROSIS: BEST PRACTICES FOR IMPROVED PATIENT OUTCOMES National Association of Managed Care NEW HORIZONS IN THE TREATMENT AND MANAGEMENT OF ATOPIC 90,000 Physicians, Inc. DERMATITIS (AD): HOW NOVEL THERAPIES ARE CHANGING THE Collaboration \3\ TREATMENT PARADIGM National Jewish Health THE 39TH ANNUAL NATIONAL JEWISH HEALTH PULMONARY & 20,000 ALLERGY UPDATE Collaboration \3\ National Kidney Foundation 12TH ANNUAL JOINT MEETING OF THE UPSTATE AND WESTERN 7,500 NEW YORK COUNCILS ON RENAL NUTRITION National Kidney Foundation STRATEGIES TO IMPROVE PATIENT OUTCOMES IN CKD-MBD 243,260 MANAGEMENT Neurologic Disease Foundation 21ST FALL MS SEMINAR--OPTIMIZING MANAGEMENT OF MS 5,995 New England Section American 85TH ANNUAL MEETING NEW ENGLAND SECTION OF THE 10,000 Urological Assn American Urological AMERICAN UROLOGICAL ASSOCIATION Association Education and Research, Inc. Not-For-Profit Hospital Corporation THYROID CANCER MANAGEMENT? AN OVERVIEW AND UPDATE OF 2,750 NEW TREATMENT OPTIONS Not-For-Profit Hospital Corporation END STAGE RENAL DISEASE FOR THE NON-NEPHROLOGIST 1,910 PeerVoice America Limited Oakstone EMERGING PARADIGMS IN ATOPIC DERMATITIS: TARGETING THE 492,850 Publishing, LLC. UNDERLYING PATHOLOGY Collaboration \3\ Penn State College of Medicine CASES FROM THE COMMUNITY: CLINICAL INVESTIGATORS 80,000 Research To Practice PROVIDE THEIR PERSPECTIVES ON EMERGING RESEARCH AND ACTUAL PATIENTS WITH ADVANCED PROSTATE CANCER]AN INDEPENDENT SATELLITE SYMPOSIUM (ISS) HELD AS A PREMIUM ANCILLARY EVENT DURING THE 2017 GENITOURINARY CANCERS SYMPOSIUM Penn State University PENN STATE HERSHEY CANCER INSTITUTE: CONTEMPORARY 3,500 TOPICS IN THYROID CANCER Pennsylvania Society of Physician MULTIPLE SCLEROSIS: A PRIMARY CARE PERSPECTIVE 4,500 Assistants Pharmacy Times Continuing Education AN AMERICAN JOURNAL OF MANAGED CARE SYMPOSIUM: 92,358 APPLYING MANAGED CARE STRATEGIES TO THE ADVANCING LANDSCAPE OF MULTIPLE SCLEROSIS Pharmacy Times Office of Continuing MANAGING ATOPIC DERMATITIS: A PHARMACIST'S OPPORTUNITY 23,200 Professional Education TO INTERVENE Collaboration \3\ Postgraduate Institute for Medicine BEST PRACTICES FOR MANAGING ADVERSE EVENTS ASSOCIATED 40,000 Clinical Care Options, LLC WITH NOVEL THERAPIES FOR PATIENTS WITH HEMATOLOGIC MALIGNANCIES Potomac Center for Medical Education NOVEL INSIGHTS IN ATOPIC DERMATITIS: PATHWAYS, 469,900 Rockpointe Corporation BIOMARKERS, AND PHENOTYPES FOR A TARGETED APPROACH President and Fellows of Harvard DIABETES AND CARDIOMETABOLIC SYNDROME IN PRIMARY CARE 10,000 College Beth Israel Deaconess Department of Medicine President and Fellows of Harvard 18TH BIENNIAL HARVARD UROLOGIC CANCER COURSE 50,000 College Dana Farber Cancer Institute President and Fellows of Harvard SURGERY OF THE THYROID AND PARATHYROID GLANDS 10,000 College Massachusetts Eye and Ear Infirmary Depart of Otolaryngology PRIME Education Inc. (PRIME) ADVANCING OUR UNDERSTANDING OF THE IMMUNOLOGY AND 289,785 TREATMENT CONSIDERATIONS IN ATOPIC DERMATITIS ProCE, Inc. Wild Iris Medical EVOLUTION OF MULTIPLE SCLEROSIS MANAGEMENT: PHARMACY'S 119,975 Education, Inc. ROLE Purdue University CiME LLC APPLYING EVIDENCE BASED MANAGEMENT STRATEGIES FOR 62,792 PATIENTS WITH MS: AN EDUCATIONAL DATA CONTINUUM Regents, University of California FOURTH ANNUAL UCLA REVIEW OF CLINICAL NEUROLOGY 5,000 Rheumatology Nurses Society American RHEUMATOLOGY NURSES SOCIETY 2016 ANNUAL CONFERENCE 25,000 Academy of Continuing Medical Education, Inc. RMEI Postgraduate Institute for A LEARNING PATHWAY IN ATOPIC DERMATITIS: ACHIEVING 989,750 Medicine SUCCESS IN ASSESSMENT AND MANAGEMENT TO IMPROVE Collaboration \3\ PATIENT OUTCOMES RMEI The Omnia-Prova Education TARGETING THE CYTOKINE PATHWAY IN RA MANAGEMENT: 199,610 Collaborative (TOPEC) IMPLICATIONS FOR NOVEL AND EMERGING IL-6 AGENTS Collaboration \3\ Robert Michael Educational Institute, THE FUTURE OF ASTHMA MANAGEMENT: PRECISION THERAPY 212,340 LLC WITH EMERGING CYTOKINE INHIBITORS Collaboration \3\ Sanford Medical Center Fargo 2016 SANFORD HEALTH NEPHROLOGY, DIALYSIS, TRANSPLANT 3,000 SYMPOSIUM Sidney Kimmel Medical College at 5TH ANNUAL DIABETES SYMPOSIUM: NEW ADVANCES & TRENDS 10,000 Thomas Jefferson University Society of Urologic Nurses and EMERGING PRACTICE PATTERNS FOR THE UROLOGY NURSE IN 50,000 Associates Plexus Communications MANAGING PATIENTS WITH ADVANCED PROSTATE CANCER: CHALLENGES AND BEST PRACTICES WITH SYSTEMIC THERAPY Southern Alliance for Physician 40TH ANNUAL SOUTHEASTERN CONSORTIUM FOR DERMATOLOGY 10,000 Specialties CME UPDATES IN PSORIASIS AND INFLAMMATORY DISORDERS Collaboration \3\ Southern Salt, Water, and Kidney Club 57TH ANNUAL SCIENTIFIC MEETING 2,500 The Medical College of Wisconsin, 25TH ANNUAL PERSPECTIVES IN UROLOGY: POINT 15,000 Inc. Carden Jennings Publishing Co., COUNTERPOINT (PCP 25) Ltd. Trustees of Boston University 2016 PCE ONCOLOGY SYMPOSIA SERIES FOR ADVANCED 150,000 Continuing Education Alliance PRACTICE PROVIDERS SPECIALIZED IN ONCOLOGY: CHOOSING INITIAL THERAPY FOR METASTATIC PROSTATE CANCER: A NEW DIRECTION Trustees of Boston University PRACTICING CLINICIANS EXCHANGE (PCE) 2016 PRIMARY CARE 50,000 Continuing Education Alliance, LLC SYMPOSIA SERIES 3 FOR NURSE PRACTITIONERS & PHYSICIAN Collaboration \3\ ASSISTANTS: RHEUMATOID ARTHRITIS: TREATING TO TARGET IN PRIMARY CARE UMA Education, Inc. dba Global SCRATCHING BENEATH THE SURFACE OF ATOPIC DERMATITIS 25,000 Education Group Collaboration \3\ UMA Education, Inc. dba Global METASTATIC PROSTATE CANCER: CURRENT TRENDS AND FUTURE 53,000 Education Group Applied Clinical LANDSCAPE Education UMA MLG, LLC MANAGING MODERATE-TO-SEVERE ATOPIC DERMATITIS IN 169,430 ADULTS: PATHOLOGY-BASED, TARGETED THERAPIES Collaboration \3\ University of Cincinnati INNOVATIVE TECHNIQUES: THE KNEE COURSE 2016 5,000 University of Cincinnati CORE Medical PRACTICE CHANGING ADVANCES: EXPANDING THE ATOPIC 112,825 Education, LLC DERMATITIS ARMAMENTARIUM Collaboration\3\ University of Cincinnati CORE Medical TYPE 2 DIABETES: MASTERING COMBINATION THERAPIES TO 42,825 Education, LLC INDIVIDUALIZE AND OPTIMIZE OUTCOMES University of Cincinnati Robert TAILORING APPROACHES TO MANAGEMENT IN PATIENTS WITH 247,170 Michael Educational Institute, LLC RHEUMATOID ARTHRITIS: WHAT'S NEW? Collaboration \3\ University of Nevada, Reno School of 2016 FALL CLINICAL DERMATOLOGY CONFERENCE 125,000 Medicine Foundation for Research and Collaboration \3\ Education in Dermatology University of Tennessee Advanced LYSIS CRISIS: PHARMACIST'S ROLE AND RESPONSIBILITY IN 70,000 Studies in Medicine THE MANAGEMENT OF TUMOR LYSIS SYNDROME University of Vermont and State NORTHERN NEW ENGLAND NEUROLOGICAL SOCIETY ANNUAL 5,000 Agricultural College MEETING WebMD Global LLC 2016 CLINICAL COURSE ON NEW DEVELOPMENTS IN ATOPIC 144,200 DERMATITIS Collaboration \3\ World Allergy Organization WAO INTERNATIONAL SCIENTIFIC CONFERENCE 2016 30,000 Collaboration \3\ ---------------------------------------------------------------------------------------------------------------- \1\ Applicant names are provided by the requestor. If applicants apply as a group for a single educational activity; all applicants may be not be identified above. The Company funds other educational activities (including fellowships and non-physician and patient education); all of which do not appear on this report, but appear on other reports on this site. \2\ ``Funding Amount'' is the amount that the Company funded during Q4, 2016 identified above based upon an agreement. Recipients are required to return any unused funds. Information on unused funds returned by the applicant on activities are not reported. ``Funding Amount'' does not include funds that may have been provided by other affiliated Sanofi Company Entities (e.g., Sanofi Pasteur). \3\ Collaboration (Shared) Funding--is the full amount of a grant funded under an agreement with Regeneron, some or all of which may be shared between the collaborating entities. Independent Medical Education Grants 1st Jan 2017-31th Mar 2017 Sanofi US and its affiliate Genzyme Corporation are committed to supporting independent medical education activities in therapeutic areas in which the Company is involved, for healthcare professionals, patients, and consumers to improve patient care and health outcomes in therapeutic areas in which the Company is engaged. Sanofi US and Genzyme Corporation are part of the Sanofi Group, a global pharmaceutical company. ---------------------------------------------------------------------------------------------------------------- Funding Amount Recipient Name(s) \1\ Activity Title ($) \2\ ---------------------------------------------------------------------------------------------------------------- AcademicCME, LLC. Applying Newer Biologic Therapies to Improve Outcomes 324,370.00 in Patients with Atopic Dermatitis Collaboration \3\ Academy for Continued Healthcare Current and Emerging Approaches to Customize Prostate 50,000.00 Learning Cancer Treatment: an eNewsletter Series Academy of Managed Care Pharmacy Management of Rare and Orphan Diseases for Improved 34,500.00 (AMCP) Patient and Payer Outcomes Advanced Studies in Medicine Elsevier Hawaii Dermatology Seminar: A Therapeutic Update on 131,590.00 Office of Continuing Medical the Management of Patients with Atopic Dermatitis Collaboration \3\ Education Advancing Knowledge in Healthcare Overcoming the Clinical Challenges of Basal Insulin 167,340.00 Medtelligence Usage in Type 2 Diabetes American Academy of PAs AAPA 2017--Rheumatology Track 5,000.00 Collaboration \3\ American Association of Clinical Using Insulin When, Where, and How It's Needed: Type 2 204,570.00 Endocrinologists Diabetes Treatment in the Modern Age American Association of Clinical AACE 2017--Treatment Advances for Challenging Patients 329,620.00 Endocrinologists ASiM with Type 2 Diabetes: The Role of Emerging Insulin Combinations American Association of Clinical Endocrine University--Thyroid Sessions 10,000.00 Endocrinologists American Association of Diabetes Improving Adherence with New Fixed-Dose Insulin 864,525.00 Educators Medscape Combination Therapy American College of Cardiology Recent Trends in Combination Therapy: Managing 50,000.00 Foundation Cholesterol Even in the Most Resistant Collaboration \3\ American College of Medical Genetics Genzyme/ACMG Foundation Clinical Genetics Fellowships 75,000.00 Foundation in Medical Biochemical Genetics American College of Rheumatology 2017 ACR Rheumatology Courses 150,000.00 Collaboration \3\ American Society of Transplantation 2017 AST Cutting Edge of Transplantation: One 38,000.00 Transplant for Life, Many Pathways to Success American Urological Association 2017 CRPC Live Forum for Urology Residents and Fellows 60,000.00 American Urological Association 2017 AUA Annual Meeting: Highlights in Advanced 75,000.00 Prostate Cancer Annenberg Center for Health Sciences Chronic Kidney Disease-Mineral and Bone Disorder- 67,905.00 at Eisenhower Translating Evidence Into Practice Annenberg Center for Health Sciences Expert Discussions: Recent Advances in Metastatic 100,000.00 at Eisenhower Clinical Care Options, Prostate Cancer Treatment LLC Annenberg Center for Health Sciences Dana Farber Master Class for Oncologists-- 25,000.00 at Eisenhower Genitourinary Cancers Track AXIS Medical Education Integrating Shared Decision Making and Guideline 40,000.00 Recommendations for Prostate Cancer Treatment AXIS Medical Education ReachMD Advancing Interdisciplinary Care in Prostate Cancer: 143,090.00 Clinical Updates for Urology and Oncology Healthcare Professionals Boston University School of Medicine-- PCE Series 2: Decision Points--Considerations for 399,897.00 Office of CME Continung Education Using New Complementary GLP-1 Receptor Agonist- Alliance, LLC Institute for Medical Insulin Combinations in Patients with T2DM and Nursing Education, Inc. Boston University School of Medicine PCE 2017 Primary Care Symposia Series 3: Joint 100,000.00 Practicing Clinicians Exchange Management: The Role of Primary Care in Rheumatoid Collaboration \3\ Arthritis Catamount Medical Education, LLC MS4: Sequencing, Switching, Escalation, and Symptom 150,000.00 Postgraduate Institute for Medicine Management Cedars-Sinai Medical Center 6th Annual Symposium on Lysosomal Storage Disorders 15,000.00 Children's Hospital of Philadelphia Genetic Counselor Fellowship in Lysosomal Storage 75,000.00 Foundation Disorders Conquer Cancer Foundation of the 2017 Genitourinary (GU) Cancers Symposium: Translating 28,000.00 American Society of Clinical Research to Value-Based and Patient-Centric Care Oncology American Society of Clinical Oncology, Inc. Consortium of Multiple Sclerosis The Science of MS Management: 2017 70,775.00 Centers Nurse Practitioner Alternatives Consortium of Multiple Sclerosis Advances In Multiple Sclerosis (AIMS) 2016: A 360 125,000.00 Centers Nurse Practitioner Approach to Translating Data into Optimal Practice Alternatives The France Foundation Duke University Fellowship in Medical Biochemical Genetics 75,000.00 Elesevier Office of Continuing Clinical Issues in Severe Asthma: Consensus and 271,605.00 Education Integritas Communications Controversies on the Road to Precision Medicine Collaboration \3\ Elsevier Office of Continuing Medical Perspectives from the American Academy of Dermatology 131,590.00 Education ASiM 2017 Meeting: Clinical Strategies and Scientific Collaboration3 Advances in Atopic Dermatitis Emory Genetics Laboratory Paul M. Fernhoff Genetic Counselor Fellowship in 75,000.00 Lysosomal Storage Diseases Endocrine Society ENDO 2017 Thyroid Sessions 75,000.00 Enquiring Minds, LLC Postgraduate Multiple Sclerosis in Pediatric Patients: Expert 60,000.00 Institute for Medicine Guidance on Overcoming Challenges in Diagnosis and Treatment Evolve Medical Education, LLC From Symptom Control to Target Treatment: The Shifting 201,325.00 Paradigm of Atopic Dermatitis Collaboration \3\ Excerpta Medica BV Elsevier Office of 2017 Genitourinary Cancers Symposium: A Therapeutic 65,795.00 Continuing Medical Education Update on the Management of Patients with Prostate Cancer Foundation of the Consortium of MS 2017 FCMSC Medical Resident Annual Meeting (CMSC) 24,700.00 Centers Scientific Scholarships Foundation of the Consortium of MS 2017-2018 Medical Student Research Scholarships 34,000.00 Centers Haymarket Medical Education Physiologic Approaches to Optimizing Glycemic Control: 309,519.00 A Pecha Kucha-Inspired CME Symposium on Long-Acting Insulins Horizon CME Fixed-Ratio GLP-1RA and Basal Insulin Formulations: 182,100.00 How and When to Use Them? Horizon CME GLP-1 RA and Basal Insulin Combinations: New Options 212,645.00 for Treatment Intensification Integrity Continuing Education, Inc. Overcoming Barriers to the Early Recognition and 149,000.00 Diagnosis of Rheumatoid Arthritis in Real-World Collaboration \3\ Practice: Strategies to Expedite Treatment to Remission Integrity Continuing Education, Inc. 2017 AAFP State Society CME Meetings and Publication 198,500.00 in Action Enduring Material Initiative--Evaluating Collaboration \3\ Newer Targeted Therapies for Patients with Rheumatoid Arthritis: Addressing Unmet Needs in the Primary Care Practice International Psoriasis Council Evolving Perspectives on Psoriasis and Atopic 100,000.00 Dermatitis: Are They Two Diseases or One Spectrum? Collaboration \3\ Lysosomal and Rare Disorders Research Genetic, Rare and Immune Disorders Symposium (GRIDS) 30,000.00 and Treatment Center Professional 2016 Education Services Group Med Learning Group Actionable Pathologic Targets in Rheumatoid Arthritis: 169,700.00 Modifying the Dysregulation of the Immune Response to Collaboration \3\ Self to Optimize Patient Outcomes Medical Learning Institute Inc. PVI ``Insights Into the Pathophysiology of Atopic 290,600.00 Peerview Institute for Medical Dermatitis: Setting the Stage for Novel Treatment Collaboration \3\ Education Inc. Options'' Medical Learning Institute Inc. PVI ``Addressing Unmet Needs in Rheumatoid Arthritis 156,730.00 Peerview Institute for Medical Through Novel Treatment Options and Enhanced Collaboration \3\ Education Inc. Physician-Patient Collaboration'' Medical Learning Institute Inc. PVI, PeerView Video in Exchange, ``Establishing a 98,750.00 PeerView Institute for Medical Therapeutic Alliance in the Management of Multiple Education Sclerosis: How Can We Better Align Treatment Preferences and Goals among Patients and Practitioners?'' Med-IQ, LLC Newborn Screening for Lysosomal Storage Disorders: 197,866.00 Recent Progress and Unanswered Questions Med-IQ, LLC Medical Insiders: Targeting IL-6 Signaling in the 125,000.00 Treatment of Rheumatoid Arthritis Collaboration3 Med-IQ, LLC Tumor Lysis Syndrome in a Rapidly Evolving Treatment 142,099.00 Landscape Med-IQ, LLC Insulin Intensification with GLP-1 Receptor Agonists: 251,110.00 Clinical Evidence and Real World Perspectives Med-IQ, LLC Viewpoints on Atopic Dermatitis: How Emerging 169,995.00 Treatments May Change the Management of Moderate to Collaboration \3\ Severe Disease Medscape Osteoarthritis of the Knee: A Patient-Simulation 250,000.00 Approach to Assessment and Management Medscape LLC Managing Patients With Rheumatoid Arthritis in the 250,000.00 Virtual Clinic Setting Collaboration \3\ Medscape LLC A Lipid Clinic in Action: How Would You Treat? 225,000.00 Collaboration \3\ Medscape LLC Close Concerns Improving Outcomes in Diabetes: Glucose Monitoring, 75,000.00 Adherence, and Individualized Treatment Medscape, LLC Autologous Stem Cell Transplantation in Multiple 182,500.00 Myeloma: Who, When, and How? Mount Sinai School of Medicine International Center for Fabry Disease 150,000.00 MS Cure Fund, Inc. 1st Quarter 2017 Multiple Sclerosis Lifestyle 19,750.00 Management Patient Education Programs National Association of Managed Care Managing Castration-Resistant Prostate Cancer: 45,000.00 Physicians Understanding the Therapeutic Landscape National Association of Managed Care What's New in the Evolving Treatment Landscape for 57,000.00 Physicians, Inc. Moderate-to-Severe Atopic Dermatitis (AD) Collaboration \3\ National Jewish Health Personalized Medicine in Severe Asthma: Applying 120,044.00 Emerging Data and Treatments to Everyday Clinical Collaboration \3\ Practice National Jewish Health Western WSAAI 55th Annual Scientific Session 15,000.00 Society of Allergy, Asthma and Collaboration \3\ Immunology (WSAAI) National Lipid Association Robert Navigating the Challenges of Prescribing PCSK9 249,835.00 Michael Educational Institute (RMEI) Inhibitors in Persistent Elevated LDL-C Collaboration \3\ National Society of Genetic New Lysosomal Storage Disease Healthcare Advocate 28,000.00 Counselors (NSGC) Emory University Workshop New York University--Langone School Department of Neurology, Division of Neurogenetics 75,000.00 of Medicine North American Center for Continuing Fixed-Ratio GLP-1 RA and Basal Insulin Combinations: A 173,365.00 Medical Education Horizon CME Complementary Approach to Treatment Intensification Norton Healthcare Foundation Celebrating MS Innovations 2017 10,000.00 NYU Post-Graduate Medical School NYU Seminar In Advanced Rheumatology 10,000.00 Collaboration \3\ Organ Donation and Transplantation 2017 National Donor Management Summit 5,000.00 Alliance Penn State College of Medicine MCM Evolving Standards of Care in Metastatic Prostate 138,400.00 Education Cancer Penn State College of Medicine PVI ``PeerView Master Class and Practicum Live--Urologists 150,000.00 Peerview Institute for Medical at the Intersection of Evidence-Based and Patient- Education Inc. Centric Prostate Cancer Care: Practical Guidance for Everyday Practice'' Penn State College of Medicine, MCM Rheumatoid Arthritis: Improving Quality of Care 100,000.00 Education Collaboration \3\ Pharmacy Times Continuing Education Managing Diabetes with Insulin/ GLP-1 Receptor Agonist 251,500.00 Combinations: A Clinical Discussion of Safety and Efficacy Data Pharmacy Times Continuing Education Information for Pharmacists: Counseling on 36,000.00 Dermatologic Conditions Collaboration \3\ Pharmacy Times Continuing Education Advances in the Treatment of Moderate to Severe Atopic 59,867.00 Dermatitis: Practice and Management Essentials for Collaboration \3\ Specialty Pharmacists Pharmacy Times Continuing Education Medical Crossfirer: Value-Based Diabetes: Managing 187,400.00 Costs Yet Improving Outcomes Pharmacy Times Continuing Education Treatment Advances in Diabetes: Evaluating the Safety 68,000.00 and Efficacy of Insulin/GLP-1 Receptor Agonist Combinations Pharmacy Times Continuing Education Atopic Dermatitis: Focusing on the Patient Care 74,000.00 Strategy in the Managed Care Setting Collaboration \3\ Ponce Medical School Foundation, Inc. The Role of the Primary Care Providers with Chronic 10,000.00 Kidney Disease Patients. Postgraduate Healthcare Education, Working Together Against Clinical Inertia: Using 126,075.00 LLC Combination Injectable Therapies in Type 2 Diabetes Postgraduate Institute for Medicine Best Practice Roadmaps and Clinical Rationale for Use 968,000.00 CMEducation Resources of Complementary Insulin plus GLP-1 Receptor Agonist Combination Therapy To Optimize PAN-Glycemic HA1c Target Goal Attainment in T2D: The Physiologic and Mechanistic Basis for New Basal Insulin plus Short- Acting GLP-1 RA Fixed-Ratio, Combination Formulations for Controlling FPG and Postprandial Hyperglycemia (PPG): Optimizing Glucose Control and Reducing Risks of Hypoglycemia and Weight Gain Postgraduate Institute for Medicine Best Practice Roadmaps and Clinical Rationale for Use 319,000.00 CMEducation Resources of Complementary Insulin plus GLP-1 Receptor Agonist Combination Therapy To Optimize PAN-Glycemic HA1c Target Goal Attainment in T2D: The Physiologic and Mechanistic Basis for New Basal Insulin plus Short- Acting GLP-1 RA Fixed-Ratio, Combination Formulations for Controlling FPG and Postprandial Hyperglycemia (PPG): Optimizing Glucose Control and Reducing Risks of Hypoglycemia and Weight Gain Postgraduate Institute for Medicine New Fixed-Ratio Combination Insulin Regimens for 341,000.00 CMEducation Resources Optimizing Comprehensive Glycemic Management In Challenging Patients with T2D: The Rationale, Evidence, and Mechanistic Basis for Fixed Ratio, Complementary Insulin plus GLP-1 RA Combinations for Achieving FPG and PPG Target Goals-Focus on Pan- Glycemic Control While Mitigating Risks of Hypoglycemia and Weight Gain Practicing Clinicians Exchange Practicing Clinicians Exchange (PCE) Directed Learning 138,800.00 Continuing Education Alliance eCourse: Updates on the Management of Knee Osteoarthritis in Primary Care: The Role of Viscosupplementation President and Fellows of Harvard New England Thyroid Club 1,500.00 College acting through Harvard Medical School Depart. of Contin Edu Beth Israel Deaconess Medical Center President and Fellows of Harvard Clinical Endocrinology 2017 5,000.00 College acting through the Harvard Medical School Department of Con The Massachusetts General Hospital PRIME Education, LLC GME-CME Today Advanced Practice in Multiple Sclerosis: 92,938.00 Focused Training for Effective Individualized Treatment Decision-Making PRIME Education, LLC Implications of Cardiovascular Outcomes Trials on 228,145.00 Lipid-Lowering Therapies Collaboration \3\ PRIME Education, LLC Applying Evidence and Lessons Learned in the 295,270.00 Management of Moderate-to-Severe Atopic Dermatitis Collaboration \3\ Pri-Med Institute, LLC Horizon CME Practical Strategies to Using Novel GLP-1 RA and Basal 972,120.00 Insulin Combinations in Clinical Practice Pri-Med Institute, LLC Horizon CME Integrating Newer Basal Insulins in Primary Care: A 956,499.91 Case-based Review Projects In Knowledge @Point of Care Rheumatologic Diseases @Point of Care 150,000.00 Collaboration \3\ Projects In Knowledge @Point of Care Multiple Sclerosis @Point of Care 133,225.00 Prostate Cancer Foundation MARS2 Retreat (Mission: Androgen Receptor Splice 10,000.00 Variant) PVI Peerview Institute for Medical PeerView Video inSession, ``Examining the Clinical 66,240.00 Education Inc. Medical Learning Implications of Late-Breaking Data on Approved and Institute Inc. Emerging Disease Modifying Therapies for Multiple Sclerosis Management: What Are the Key Learnings From Boston?'' Regents of the University of 5th Annual UC San Diego Essentials and Advances in 5,000.00 California Apheresis Regents of the University of Transplant Immunosuppression 2017: Achieving Long-Term 35,000.00 Minnesota Success Research To Practice What Urologists Want to Know: Addressing Current 85,000.00 Questions and Controversies in the Management of Early and Advanced Prostate Cancer--An Independent Satellite Symposium (ISS) Held in Conjunction with the 2017 American Urological Association (AUA) Annual Meeting Rocky Mountain MS Center MS 101 2017 Programs 10,000.00 Rush University Medical Center Plexus Realizing Improved Outcomes in Advanced Prostate 80,000.00 Communications Cancer through Evolving Research and Emerging Treatment Paradigms: Challenges and Opportunities Rush University Medical Center Plexus VHA Oncology Clinical Forums: ``Current Treatment 100,000.00 Communications Strategies for Advanced Prostate Cancer: Sequencing Therapies and Incorporating Novel Approaches'' Society for Inherited Metabolic 2016 North American Metabolic Academy 20,000.00 Disorders St. Joseph's Regional Medical Center Introduction to Clinical Transplantation; Renal 1,500.00 Transplantation--An Overview The France Foundation State Chapter Meetings: A Physiological Approach to 357,120.00 Combination Therapies: Improving Glycemic Control in T2DM The France Foundation A Bright Outlook on New and Emerging RA Management 145,330.00 Options: What Would You Do? Collaboration \3\ The France Foundation Calibre Famous People with Diabetes: A Case Study Exploring 552,210.00 Institute for Quality Medical the Use of New and Emerging Basal Insulins Education The Medical College of Wisconsin, 27th International Prostate Cancer Update 20,000.00 Inc. Carden Jennings Publishing Co., Ltd. The Medical College of Wisconsin, Optimizing Stem Cell Mobilization for Autologous 223,000.00 Inc. Carden Jennings Publishing Co., Transplantation in Myeloma Ltd. The National Multiple Sclerosis The Living Well with MS Conference (North Florida) 3,500.00 Society, North Florida Chapter The Trustees of the University of Lysosomal Storage Disease Fellowship 75,000.00 Pennsylvania The University of Chicago 22nd Annual University of Chicago Developmental 5,000.00 Therapeutics Symposium The University of Texas MD Anderson 7th Current Concepts in the Management of Thyroid & 25,000.00 Cancer Center Parathyroid Neoplasms Tufts Medical Center Hypertrophic Cardiomyopathy--A Contemporary and 20,000.00 Treatable Disease: Diagnosis, Heart Failure Management, and Prevention of Sudden Death UC Irvine University of California, Irvine Lysosomal Storage 56,857.68 Diseases Patient and Family Educational Grant UCI Office of Continuing Medical Nephrology Grand Rounds 2,000.00 Education University of California Irvine UMA Education Inc., dba Global Optimizing Outcomes in Atopic Dermatitis 106,250.00 Education Group, Physicians' Collaboration \3\ Education Resource University of Alabama at Birmingham 2017 Fabry Fellowship 75,000.00 UMA Education, Inc.: dba Global Going Deeper on Atopic Dermatitis: Pathophysiology to 239,640.92 Education Integritas Communications the Management of Moderate-to-Severe Disease Collaboration \3\ University of Arkansas for Medical Tackling Type 2 Diabetes at the Community Level: A 90,000.00 Sciences MedIQ Focused QI Initiative to Overcome Local Challenges to Patient Health University of Cincinnati Advances in MauiDerm 2017 45,000.00 Cosmetic and Medical Dermatology Collaboration \3\ University of Kansas Medical Center/ Neuromuscular Review Course 2017 20,000.00 Kansas Endowment Association University of Kansas School of Neuromuscular Medicine Fellowship 75,000.00 Medicine University of Massachusetts Medical The Physiologic and Mechanistic Rationale for 341,000.00 School CMEducation Resources Achieving HA1c Target Goals with Basal Insulin In Vulnerable Patients with Type 2 Diabetes: Focus on the Safety-Efficacy Equation, Patient Selection, Switching, Dosing and Physiologic, PK/PD Profiles of Long-Acting Basal Insulin Formulations University of Massachusetts Medical The iQ&A Case-By-Case interactive Diabetes 178,000.00 School CMEducation Resources Intelligence Zone: Practical, Real World Strategies for Deploying Fixed-Ratio Insulin Combinations in T2D- National Experts in Diabetes Focus on Patient Identification, Dose Titration, Pan-Glycemic (FPG and PPG) Control, Mechanistic Complementarity, and Optimizing the Safety-Weight-Efficacy Equation in Patients with Diabetes University of Massachusetts Medical The iQ&A Case-By-Case Interactive Diabetes 178,000.00 School CMEducation Resources Intelligence Zone: Focus on Practical Aspects of Using Physiologic, Long-Acting Basal Insulin to Optimize Glycemic Management in T2D University of Rochester School of 2017 Society for Investigative Dermatology Annual 50,000.00 Medicine and Dentistry Society for Meeting Collaboration \3\ Investigative Dermatology University of Massachusetts Medical The iQ&A Case-By-Case Interactive Diabetes 178,000.00 School CMEducation Resources Intelligence Zone: Focus on Practical Aspects of Using Physiologic, Long-Acting Basal Insulin to Optimize Glycemic Management in T2D University of Rochester School of 2017 Society for Investigative Dermatology Annual 50,000.00 Medicine and Dentistry Society for Meeting Collaboration3 Investigative Dermatology University of Vermont and State The 28th Annual Eastern Winter Dermatology Conference Collaboration \3\ Agricultural Colle 10,000.00 UT Southwestern Medical Center 39th Annual Carrell-Krusen Neuromuscular Symposium 5,000.00 Collaboration \3\ World Allergy Organization Collaboration on Severe Asthma (COSA) 35,000.00 Collaboration \3\ ---------------------------------------------------------------------------------------------------------------- \1\ Applicant names are provided by the requestor. If applicants apply as a group for a single educational activity; all applicants may be not be identified above. The Company funds other educational activities (including fellowships and non-physician and patient education); all of which do not appear on this report, but appear on other reports on this site. \2\ ``Funding Amount'' is the amount that the Company funded during Q1, 2017 identified above based upon an agreement. Recipients are required to return any unused funds. Information on unused funds returned by the applicant on activities are not reported. ``Funding Amount'' does not include funds that may have been provided by other affiliated Sanofi Company Entities (e.g., Sanofi Pasteur). \3\ Collaboration (Shared) Funding--is the full amount of a grant funded under an agreement with Regeneron, some or all of which may be shared between the collaborating entities. Independent Medical Education Grants 1st April 2017-30th June 2017 Sanofi US and its affiliate Genzyme Corporation are committed to supporting independent medical education activities in therapeutic areas in which the Company is involved, for healthcare professionals, patients, and consumers to improve patient care and health outcomes in therapeutic areas in which the Company is engaged. Sanofi US and Genzyme Corporation are part of the Sanofi Group, a global pharmaceutical company. ---------------------------------------------------------------------------------------------------------------- Funding Amount Recipient Name(s) \1\ Activity Title ($) \2\ ---------------------------------------------------------------------------------------------------------------- AKH Inc., Advancing Knowledge in A Multidisciplinary Approach to the Treatment of 149,125.00 Healthcare Center of Excellence Prostate Cancer: Providing Therapies that Improve Media, LLC--An affiliate of The Lynx Overall Survival and Quality of Life Group AKH Inc., Advancing Knowledge in Endocrine Nurses Society Symposium 2017 Thyroid 5,000.00 Healthcare Endocrine Nurses Society Sessions American Academy of Dermatology The The Future is Finally Here--Targets of the New Atopic 75,000.00 France Foundation Dermatitis Drugs Collaboration \3\ American Academy of PAs AAPA 2017--Orthopaedics Track 10,000.00 American Association of Clinical Current Landscape in Medullary Thyroid Cancer: Updates 198,425.00 Endocrinologists for Clinicians American Association of Clinical Georgia-AACE April Dinner Program: New Developments in 3,276.00 Endocrinologists Thyroid Cancer American College of Allergy, Asthma & EAC 2017 Update in Allergy, Asthma & Immunology 10,000.00 Immunology Eastern Allergy Collaboration \3\ Conference American College of Allergy, Asthma & Society of Allergy, Asthma & Immunology CSAAI 2017 A 10,000.00 Immunology; California Midsummer Night's Wheeze American College of Medical Genetics Genzyme/ACMG Foundation Clinical Genetics Fellowships 75,000.00 Foundation in Biochemical Genetics American Society of Clinical Oncology 2017 ASCO Annual Meeting Genitourinary Cancer 28,000.00 Oncology, Inc. Conquer Cancer Tracks Bundle--Prostate and Nonprostate Foundation of the American Society of Clinical American Thoracic Society ATS 2017 International Conference--Selected Sessions 20,000.00 in Asthma Collaboration \3\ Ann & Robert H. Lurie Children's Lysosomal Storage Disease Training Program for Genetic 75,000.00 Hospital of Chicago Counselors Med Learning Group Novel Formulations of Basal Insulins for Patients with 249,050.00 Diabetes: A New Opportunity to Optimize Outcomes Med Learning Group A Virtual Reality View of Biologic Agents: Targeted 375,000.00 Therapies for the Management of Moderate-to-Severe Collaboration \3\ Atopic Dermatitis in Adults Medical Learning Institute Inc. PVI Enhancing Autologous Hematopoietic Stem Cell 108,050.00 Peerview Institute for Medical Transplantation Through Individualized Stem Cell Education Inc. Mobilization Strategies Medical Learning Institute Inc. PVI PeerView Video in Session ``New Developments in 154,980.00 Peerview Institute for Medical Inflammatory Dermatologic and Respiratory Diseases: Collaboration \3\ Education Inc. Clinical Highlights From Helsinki'' Medscape LLC Basal Insulin in Today's Clinical Practice 500,000.00 Environment: Improving Use for Better Patient Outcomes Medscape LLC Clinical Advances in Atopic Dermatitis 950,000.00 Collaboration \3\ Medscape LLC A Medscape Studio Series on Modern Approaches for 125,000.00 Optimizing Care in MS Michigan State Medical Society Rheumatology Update 5,000.00 Collaboration \3\ MSWorld Inc. Comprehensive Proposal for 2017 MS World Conference 50,000.00 Coverage MSWorld Inc. 2017 ``MSWorld Talks'' Series 55,000.00 Muscular Dystrophy Association MDA Care Center Open House at Nemours Children's 500.00 Hospital National Association of Managed Care Individualizing Treatment in the Management of Type 2 57,000.00 Physicians, Inc. Diabetes: Novel Therapies for Improved Patient Outcomes National Comprehensive Cancer Network Prostate Cancer Patient Management Simulator 35,000.00 National Lipid Association Vindico Back to the Future: Clinical Experience with and 50,000.00 Medical Education Access to Lipid-Lowering Agents of the Past, Present, Collaboration \3\ and Future--A National Lipid Association Expert Discussion and Town Hall National Medical Association Endocrinology, Diabetes, and Metabolism Symposium 250,000.00 Current and Emerging Interventions: Saving Lives and Limbs by Improving Diabetes Care National Medical Association MODERN ERA DIAGNOSIS, TREATMENT AND MANAGEMENT OF 15,000.00 PATIENTS WITH PROSTATE CANCER National Multiple Sclerosis Society National MS Society Monthly Email Newsletter 75,000.00 National Society for Cutaneous 2017 Real World Dermatology for Residents 40,000.00 Medicine Collaboration \3\ OhioHealth OhioHealth Multiple Sclerosis Symposium 5,000.00 Oncology Nursing Society 42nd ONS Annual Congress and two Oncology Updates 25,000.00 Regional Programs Oregon Health & Science University 7th International Symposium on Gait & Balance in 13,108.00 Multiple Sclerosis: Neuroplasticity and Rehabilitation in MS Palm Beach County Medical Society Managing Thyroid Disease for the Primary Care Provider 5,000.00 Services Palm Beach Diabetes & Endocrine Specialists, P.A. Penn State College of Medicine i3 Selecting Optimal Therapeutic Strategies for Patients 50,000.00 Health With Differentiated and Medullary Thyroid Cancer Penn State College of Medicine PVI ``Science and Stories: Making the Most of the Complex 146,030.00 PPerview Institute for Medical Treatment Landscape in Prostate Cancer'' Education Inc. Pharmacy Times Continuing Education Reaching Out: A Pharmacist's Curriculum to Optimize 251,240.00 Insulin Therapy Through Patient Engagement and Management Postgraduate Healthcare Education, How Specialty Pharmacists Can Enhance Patient-Driven 58,000.00 LLC Postgraduate Institute for Care in Multiple Sclerosis Medicine Postgraduate Healthcare Education, Providing Relief to Patients with Atopic Dermatitis: 137,250.00 LLC Postgraduate Institute for How Pharmacists Can Help Collaboration \3\ Medicine Potomac Center for Medical Education MULTIPLE SCLEROSIS CARE IN THE HOSPITAL SETTING: Novel 75,000.00 Rockpointe Corporation Neuroimaging Techniques, Individualized Treatment Strategies, and Management of Comorbidities Practicing Clinicians Exchange Boston New and Emerging Strategies in T2DM Using Basal 375,000.00 University School of Medicine Insulin PRIME Education, LLC Advances in Psoriatic Diseases and Atopic Dermatitis 150,000.00 for Clinicians in Federal and Public Healthcare Collaboration \3\ Settings PRIME Education, LLC When Statin Therapy Isn't Enough 192,435.00 Collaboration \3\ ProCE Inc. Atopic Dermatitis: A Specialty Pharmacy 360-Degree 42,250.00 View of the Patient Collaboration \3\ Projects In Knowledge MedImages Cases: Multiple Sclerosis 125,000.00 Purdue University MCM Education Managing Type 2 Diabetes: The Role of Insulin 175,000.00 Regents of the University of Colorado Practical Ways to Achieve Targets in Diabetes Care 150,000.00 Regents of the University of Pharmacotherapy of Inherited Metabolic Diseases Post- 75,000.00 Minnesota Doctoral PharmD Fellowship Society for Translational Oncology Conference Perspectives: Lessons Learned 40,000.00 St. Vincent Neuroscience Institute, MS: A Personal Approach 3,000.00 St. Vincent Hospital, Indianapolis The University of Chicago MCM Evolving Paradigms for Insulin Therapy of Type 2 150,000.00 Education Diabetes Tisch Multiple Sclerosis Research Tisch MS Research Center 20th Annual MS Patient 50,000.00 Center of New York Symposium UMA Education Inc., dba Global Coalition United for Better Eczema Care (CUBE-C) 320,000.00 Education Group FactoRx Health Collaboration \3\ Advocacy Partners National Eczema Association Med Ed Consulting UMA Education Inc., dba Global R.A.P.I.D.--Rheumatoid Arthritis: A Primary Care 150,000.00 Education Group FactoRx MedEd Initiative for Improved Diagnosis and Outcomes Collaboration \3\ Consulting Improve CME, LLC Indegene UMA Education Inc., dba Global The Role of Concentrated Insulins and Insulin 127,500.00 Education Group Physicians' Combinations in Overcoming Insulin Resistance and Education Resource Improving Adherence A Patient Centered Multidisciplinary Approach UMA Education Inc., dba Global Medical Crossfirer: Advances in Atopic Dermatitis: A 157,000.00 Education Group Physicians' Multidisciplinary, Patient-Centered Approach to Education Resources Addressing Unmet Therapeutic Needs UMA Education Inc., dba Global Effective Management of Atopic Dermatitis: New 99,585.00 Education Group Physicians' Approaches to Guiding Everyday Practice Collaboration \3\ Education Resources UMA Education Inc., dba Global Getting Beneath the Surface in Atopic Dermatitis: A 164,330.00 Education Group Physicians' Patient-Centered Approach to Optimize Outcomes Collaboration \3\ Education Resources UMA Education, Inc. dba Global Best Practices: Efficient and Cost Effective 155,884.00 Education Group Tarsus Cardio Inc. Management of the Authorization Process Collaboration \3\ dba Cardiometabolic Health Congress ---------------------------------------------------------------------------------------------------------------- \1\ Applicant names are provided by the requestor. If applicants apply as a group for a single educational activity; all applicants may be not be identified above. The Company funds other educational activities (including fellowships and non-physician and patient education); all of which do not appear on this report, but appear on other reports on this site. \2\ ``Funding Amount'' is the amount that the Company funded during Q2, 2017 identified above based upon an agreement. Recipients are required to return any unused funds. Information on unused funds returned by the applicant on activities are not reported. ``Funding Amount'' does not include funds that may have been provided by other affiliated Sanofi Company Entities (e.g., Sanofi Pasteur). \3\ Collaboration (Shared) Funding--is the full amount of a grant funded under an agreement with Regeneron, some or all of which may be shared between the collaborating entities. Independent Medical Education Grants 1st July 2017--30th Sep 2017 Sanofi US and its affiliate Genzyme Corporation are committed to supporting independent medical education activities in therapeutic areas in which the Company is involved, for healthcare professionals, patients, and consumers to improve patient care and health outcomes in therapeutic areas in which the Company is engaged. Sanofi US and Genzyme Corporation are part of the Sanofi Group, a global pharmaceutical company. ---------------------------------------------------------------------------------------------------------------- Funding Amount Recipient Name(s) \1\ Activity Title ($) \2\ ---------------------------------------------------------------------------------------------------------------- American Academy of PAs 2017 Adult Hospital Medicine Boot Camp 5,490.00 American Association of Clinical Current Landscape in Medullary Thyroid Cancer: Updates 147,769.00 Endocrinologists for Clinicians American Association of Clinical Illinois-AACE 7th Annual Meeting 5,000.00 Endocrinologists American Association of Clinical New Jersey Chapter of the American Association of 5,000.00 Endocrinologists Clinical Endocrinologists American College of Allergy, Asthma & Thursday Morning Session: Atopic Dermatitis Yardstick 40,000.00 Immunology Collaboration \3\ American College of Medical Genetics Genzyme ACMG Foundation Clinical Genetics Fellowships 75,000.00 Foundation in Biochemical Genetics American Society of Transplant 11th Annual Surgical Fellows Symposium 44,500.00 Surgeons American Society of Transplantation 2017 Fellows Symposium on Transplantation 40,000.00 American Urological Association Practical Management of Metastatic Prostate Cancer: 75,000.00 Guidelines and Beyond Ann & Robert H. Lurie Children's Lysosomal Storage Disease Training Program for Genetic 75,000.00 Hospital of Chicago Counselors Ascendant Limited Albert Einstein The Team-based Approach to Diagnosing and Managing 134,868.75 College of Medicine and Montefiore African American Patients with MS: A Quality Medical Center, Center for CME Improvement Curriculum Carden Jennings Publishing Co., Ltd. 27th International Prostate Cancer Update 20,000.00 The Medical College of Wisconsin, Inc. Cleveland Clinic Educational Pitfalls in Diagnosis of Multiple Sclerosis 25,000.00 Foundation Clinical and Patient Educators Oncology Emergency Essentials: Addressing Tumor Lysis 117,394.90 Association Syndrome in Your Practice Carden Jennings Publishing Co., Ltd. 27th International Prostate Cancer Update 20,000.00 The Medical College of Wisconsin, Inc. Cleveland Clinic Educational Pitfalls in Diagnosis of Multiple Sclerosis 25,000.00 Foundation CMEducation Resources Postgraduate Optimizing Insulin-Based Glycemic Control in Type 2 500,000.00 Institute for Medicine Diabetes: The Foundational Role and Physiologic Rationale for Long-Acting Insulin: An Evidence-Based Roadmap for Clinical Success-Focus on the Safety- Efficacy and PK/PD Profiles of New Long-Acting Physiologic Insulin Formulations Connecticut Pharmacists Association Current and Emerging Therapies in Multiple Sclerosis 10,000.00 Continuing Education Alliance PCE Interactive eCourse Series: New Pathways in Atopic 149,534.00 Practicing Clinicians Exchange Dermatitis: Novel Therapies for Optimizing Outcomes Collaboration \3\ Dignity Health MandatoryCE 2017 Arkansas Diabetes Symposium: Focus on Treatment 25,000.00 Advances, Nutrition Therapy, Obesity and Metabolic Syndrome DKBmed The Johns Hopkins University The Johns Hopkins University School of Medicine 120,000.00 School of Medicine eDiabetes Review Volume 3 Duke University Duke Solid Organ Transplant Summit 30,000.00 E&S MedEd Group, Inc. American Zeroing In on A1C Targets: Pinpointing the Optimal 284,660.00 Association of Diabetes Educators Basal Insulin Strategy in Every Patient with Type 2 Diabetes Elsevier Office of Continuing Evolving Treatment Paradigms for Rheumatoid Arthritis: 75,000.00 Education Integritas Communications Translating Comprehensive Patient Evaluations Into Collaboration \3\ Personalized Therapy Elsevier Office of Continuing Medical MS Paris 2017: Clinical Updates on Disease Modifying 161,920.00 Education AcademicCME Therapies to Improve Outcomes for Patients with Multiple Sclerosis Enquiring Minds, LLC Postgraduate Are My Patients Taking Their Meds as Prescribed? 106,205.00 Institute for Medicine Addressing Suboptimal Therapeutic Response Among Patients with MS Euforea IVZW European Summit on the Prevention and Self-Management 10,676.50 of Airway Diseases Excel Continuing Education Expanding Horizons in ASMD/Niemann-Pick Disease 68,175.00 Focus Medical Communications, LLC 2017 International Coalition of Rheumatology Education 100,000.00 Siyemi Learning Providers Initiative Foundation for Orthopaedic Research & 2017 Orthopaedics for the Primary Care Practitioner & 5,000.00 Education (FORE) Rehabilitation Global Academy Medical Education Innovative Techniquesr: The Knee, Hip and Shoulder 25,000.00 University of Cincinnati Course Haymarket Medical Education Haymarket Race to Remission: Timely Diagnosis and Early, 273,823.00 Media/MIMS Intensive Treatment in Rheumatoid Arthritis Care: A Collaboration \3\ Patient-Centered Global Curriculum Aligning With the Spirit of World Arthritis Day Indiana Academy of Physician ``Multiple sclerosis 2017--Update on diagnostic 5,000.00 Assistants criteria, clinical descriptors, and treatments'' International Niemann-Pick Disease Support for the development and management of the 117,706.45 Registry International Niemann Pick Disease Registry Kentucky Academy of Physician Joint Injection Workshop 5,000.00 Assistants Letters & Sciences Advances in Multiple Sclerosis Research & Practice, 69,000.00 Annual CNE Conference Hosted by Columbia University, MS Clinical Care and Research Center Mattel Children's Hospital UCLA Post Doc Fellowship 63,000.00 Med Learning Group Pathologic Targets in Rheumatoid Arthritis: Modifying 288,350.00 the Immune Response to Optimize Patient Outcomes Collaboration3 Med Learning Group A 3-Dimensional View of Recent Advances in 353,460.00 Personalized Treatment for the Management of Collaboration \3\ Uncontrolled Asthma Med-IQ, LLC Clinical and Translational Insights in Pompe Disease: 189,407.00 Disease Pathology, Patient Identification, and Treatment Medscape LLC CME LIVE: A Late-Breaking Update on PCSK9 Inhibitors 500,000.00 and Cardiovascular Outcomes Collaboration \3\ Medscape LLC Advances in Rheumatoid Arthritis 2017: What's the 99,500.00 Conference Buzz? Collaboration \3\ MedStar Georgetown University 4th Annual Current Issues in the Care of Dialysis and 10,000.00 Hospital Transplant Patients Montefiore Medical Center MRCME, LLC PCSK9 Inhibitor Therapy for Dyslipidemia: Implications 399,845.00 of Outcome Trial Results and a Look to the Future Collaboration\3\ MS Views and News The 2017 Multiple Sclerosis Symposium of South Florida- 20,000.00 The Neurological Aspects of MS and Beyond Collaboration \3\ National Association for Continuing Utilizing Concentrated Insulins: A New Strategy for 260,000.00 Education the Insulin Resistant Patient National Association of Managed Care New Targets in the Therapeutic Landscape for Moderate- 57,000.00 Physicians, Inc. to-Severe Atopic Dermatitis (AD): What Does Managed Collaboration \3\ Care Need to Know? National Gaucher Foundation, Inc. Medical Diagnostic/Testing Program 150,000.00 Collaboration \3\ National Multiple Sclerosis Society Life-Changing Breakthroughs: African American 10,000.00 Education Conference National Organization for Rare NORD Continuing Medical Education 80,000.00 Disorders University of Massachusetts Medical School Oregon Health & Science University 17th Annual Pacific Northwest Prostate Cancer 20,000.00 Conference Penn State College of Medicine MCM Contemporary Management of Type 2 Diabetes 166,694.00 Education Penn State College of Medicine PVI PeerView In Session, ``Analyzing the Latest Evidence 151,480.00 Peerview Institute for Medical in Atopic Dermatitis: Clinical Updates From Geneva'' Collaboration \3\ Education Inc. Pennsylvania Society of Physician ``Joint Injections'' 5,500.00 Assistants Collaboration \3\ Pharmacy Times Continuing Education Advances in Insulin and Insulin Combination Therapies: 68,300.00 Opportunities for Convenient Care Providers to Improve Patient Outcomes PlatformQ Health Education, LLC From Novice to Expert: A Series in Multiple Sclerosis 100,000.00 Consortium of Multiple Sclerosis Management Centers Nurse Practitioner Alternatives Postgraduate Healthcare Education, Understanding the Mechanisms of DMARD Therapy in 53,500.00 LLC Postgraduate Institute for Patients with Rheumatoid Arthritis Collaboration \3\ Medicine Postgraduate Institute for Medicine The Importance of Early Diagnosis and Timely Access to 349,850.00 Global Academy for Medical Education Treatment of RA Collaboration \3\ Postgraduate Institute for Medicine Defining Personalized Care Plans in Metastatic 60,000.00 i3 Health Castration-Resistant Prostate Cancer Postgraduate Institute for Medicine Managing Multiple Sclerosis: Current Treatment and 150,000.00 Impact Education, LLC Care Management Strategies for Managed Care PRIME Education, LLC Scaling-Up Shared Decision-Making in Multiple 162,382.50 Sclerosis Treatment Projects in Knowledge The Art & Science of Multiple Sclerosis Management 175,000.00 Projects in Knowledge @Point of Care Atopic Dermatitis @Point of Care 200,000.00 Collaboration \3\ Regents of the University of Michigan Pompe Disease Patient Educational Booklet 2,777.00 Collaboration \3\ Regents University of California Los Educational Seminars for Patients, Families, and 20,000.00 Angeles Friends 2017-2018 Research To Practice Year in Review--A Four-Part Multi-tumor Regional CME 40,000.00 Symposia Series Focused on the Application of Emerging Research Information to the Care of Patients with Common Cancers: Genitourinary Cancers Module Rheumatology Nurses Society RNS 2017 Annual Conference 25,000.00 Collaboration \3\ RMEI Postgraduate Institute for Achieving Success in RA Assessment and Management: A 349,547.00 Medicine Learner Pathway to Improve Patient Outcomes Collaboration \3\ Suffolk Academy of Medicine Long The Long Island Allergy & Asthma Society 24th Annual 10,000.00 Island Allergy & Asthma Society Scientific Meeting Collaboration \3\ Suffolk Academy of Medicine Long The Long Island Allergy & Asthma Society 24th Annual 10,000.00 Island Allergy & Asthma Society Scientific Meeting Collaboration3 The Regents of UC/Office of Cont Med UCLA Review of Clinical Neurology 2,500.00 Educ Tufts University School of Medicine Severe Asthma: Inspiring Change 216,712.50 DKBmed Collaboration \3\ UMA Education, Inc. dba Global Closing the Gap Created by Clinical Inertia: New 207,845.00 Education Group Tarsus Cardio Inc. Strategies for T2DM Treatment dba Cardiometabolic Health Congress Universitatsmedizin Rostock, Albrecht- Recent advances in rare diseases: Gaucher disease as a 25,000.00 Kossel-Institute for model (RARD 2017) Neuroregeneration (AKos) University of Louisville Research 10th Annual Perspectives in Rheumatic Diseases 12,500.00 Foundation Global Academy for presented by Rheumatology News, Internal Medicine Collaboration \3\ Medical Education, LLC Postgraduate News & Family Practice News Institute for Medicine University of Nevada, Reno School of 2017 Fall Clinical Dermatology Conference 125,000.00 Medicine Foundation for Research and Education in Dermatology Vindico Medical Education, LLC When Severe Asthma is Out of Control: Examining 137,340.00 Phenotypic Approaches to Treatment Collaboration \3\ Yale New Haven Hospital New and Emerging Multiple Sclerosis Therapies 15,000.00 Yale School of Medicine The Yale-Cambridge Transplantation Symposium: Donor 20,000.00 Decision-Making in an Era of Advanced Medical Complexity ---------------------------------------------------------------------------------------------------------------- \1\ Applicant names are provided by the requestor. If applicants apply as a group for a single educational activity; all applicants may be not be identified above. The Company funds other educational activities (including fellowships and non-physician and patient education); all of which do not appear on this report, but appear on other reports on this site. \2\ ``Funding Amount'' is the amount that the Company funded during Q3, 2017 identified above based upon an agreement. Recipients are required to return any unused funds. Information on unused funds returned by the applicant on activities are not reported. ``Funding Amount'' does not include funds that may have been provided by other affiliated Sanofi Company Entities (e.g., Sanofi Pasteur). \3\ Collaboration (Shared) Funding--is the full amount of a grant funded under an agreement with Regeneron, some or all of which may be shared between the collaborating entities. Independent Medical Education Grants 1st Oct 2017-31th Dec 2017 Sanofi US and its affiliate Genzyme Corporation are committed to supporting independent medical education activities in therapeutic areas in which the Company is involved, for healthcare professionals, patients, and consumers to improve patient care and health outcomes in therapeutic areas in which the Company is engaged. Sanofi US and Genzyme Corporation are part of the Sanofi Group, a global pharmaceutical company. ---------------------------------------------------------------------------------------------------------------- Funding Amount Recipient Name(s) \1\ Activity Title ($) \2\ ---------------------------------------------------------------------------------------------------------------- AcademicCME, LLC. Applying Individualized Therapeutic Strategies of 98,000.00 Switching and Sequencing to Improve Outcomes for Patients with Multiple Sclerosis: The Right Treatment at the Right Time for the Right Patient Albert Einstein College of Medicine/ Atopic Dermatitis (Eczema) Challenges: Recognition and 108,682.50 Montefiore Medical Center M2 Assessment in Primary Care Collaboration \3\ Communications American Association of Clinical New Jersey-AACE January Dinner Program: Treatment of 2,591.00 Endocrinologists Advanced Thyroid Cancer American Association of Clinical Minnesota/Midwest Chapter of the American Association 5,000.00 Endocrinologists of Clinical Endocrinologists 8th Annual Meeting American College of Allergy, Asthma & Biologics in Atopic Dermatitis Workshop 25,320.00 Immunology American College of Allergy, Asthma & WSAAI 2018: 56th Annual Scientific Session 20,000.00 Immunology Western Society of Collaboration \3\ Allergy, Asthma & Immunology Annenberg Center for Health Sciences 10th Annual Linda Morgante MS Nurse Leadership Program 35,000.00 at Eisenhower Academy for Continued Healthcare Learning (ACHL) Association pulmonaire du Quebec Biennale de l'Espace francophone de la pneumologie 12,150.00 Boston University School of Medicine Management of Knee Osteoarthritis in Primary Care: The 200,000.00 Practicing Clinicians Exchange Case for Viscosupplementation Continuing Education Alliance LLC California Optometric Association 2017 Monterey Symposium 10,400.00 Cedars-Sinai Medical Center 7th Annual Symposium on Lysosomal Storage Disorders 15,000.00 Children's Hospital of Philadelphia Lysosomal Storage Disease (LSD) Fellowship 75,000.00 Foundation Cleveland Clinic--Lou Ruvo Center for Advancing Therapeutics for Multiple Sclerosis 5,000.00 Brain Health Cleveland Clinic Center for Clinical Updates on Fabry Disease: Diagnosis Through 159,750.00 Continuing Medical Education Treatment Medscape LLC Cleveland Clinic Educational Medical Dermatology Therapy Update: Autoimmune 10,000.00 Foundation Diseases, Chronic Inflammatory and Advanced Malignancies Cleveland Clinic Educational 6th Annual Basic & Clinical Immunology for the Busy 25,000.00 Foundation Clinician CME Outfitters, LLC Peeking Beneath the Surface of Atopic Dermatitis: 200,000.00 Testing Your Skills from Pathogenesis to Treatment Division of Medical Genetics and Better Outcomes of Lysosomal Diseases (BOLD) 75,000.00 Genomic Medicine Fellowship Elsevier Office of Continuing Medical THE LSD DEBATE: OPTIMIZING DIAGNOSIS AND FUTURE 248,465.00 Education Excerpta Medica BV MANAGEMENT Elsevier Office of Continuing Medical Clinical Issues in Severe Asthma: Debates and 628,867.00 Education Integritas Communications Discussions About Personalizing Patient Management Elsevier Office of Continuing Medical Clinical Issues in Atopic Dermatitis: Discussions and 784,641.50 Education Integritas Communications Debates on Managing Moderate-to-Severe Disease Collaboration \3\ Emory University The Paul M. Fernhoff Genetic Counseling Fellowship in 75,000.00 the Lysosomal Storage and Other Genetic Disorders EUFOREA IVZW European Rhinology Research Forum 18,000.00 European Respiratory Society ERS Satellites 72,000.00 European Society for Dermatological 47th ESDR Meeting 2017 44,400.00 Research Excel Continuing Education Responding to the Challenge of Pompe Disease 100,165.00 (satellite symposium at 2018 World Congress) George Washington University (GW) American Contact Dermatitis Society-Frontiers in 10,000.00 Office of Continuing Education in Dermatitis 2017 Collaboration \3\ the Health Profession (CEHP) American Contact Dermatitis Society Global Education Group Integritas Clinical Issues in Atopic Dermatitis: Discussions and 177,074.00 Communications Debates on Managing Moderate-to-Severe Disease Collaboration \3\ Icahn School of Medicine at Mount 4th NY Masters Course in Endocrinology and Endocrine 10,000.00 Sinai Surgery Collaboration \3\ Icahn School of Medicine at Mount 20th Annual Mount Sinai Winter Symposium ``Advances in 20,000.00 Sinai Medical & Surgical Dermatology'' Indiana Academy of Physician ``Anterior Knee Pain and Osteoarthritis'' 5,000.00 Assistants Institute for Medical and Nursing MEDS 2018: Going Flat-Out for Glycemic Control: The 381,055.00 Education, Inc. Role of New Basal Insulins in Patient-Centered T2DM Management Institute for Medical and Nursing MEDS 2018: Rationale, Recognition, and 354,830.00 Education, Inc. Recommendations: Expert Perspectives on Combining Basal Insulin and GLP-1 RAs to Intensify Treatment of T2DM Kidney Disease Improving Global KDIGO Controversies Conference on Glomerular Diseases 25,000.00 Outcomes (KDIGO) Med Learning Group Recognizing the Connection: A View into the Parallels 225,000.00 between Asthma and Nasal Polyps Medical Education Resources, Inc. Basic concepts in eczema diagnosis and management 20,000.00 Dermveda Inc. Medical Learning Institute Inc. PVI, PeerView ``Ascertaining the Potential Clinical 80,000.00 Peerview Institute for Medical Implications of The Latest Data on Approved and Education Inc. Emerging Disease Modifying Therapies for Multiple Sclerosis Management: A Recap from Paris'' Medical Learning Institute Inc. PVI, PeerView in Session, ``Exploring the Latest Data in 74,490.00 PeerView Institute for Medical the Treatment of Uncontrolled Persistent Asthma: Collaboration \3\ Education, Inc. Clinical Highlights from San Diego'' Medical Learning Institute PVI, PeerView Talks, ``A Patient-Centered Approach to the 153,580.00 PeerView Institute for Medical Diagnosis and Treatment of Atopic Dermatitis in Collaboration \3\ Education Adults: An Expert's Story'' Med-IQ, LLC Pragmatic Approaches to Improving Insulin Introduction 254,623.00 and Integration in T2DM:Patient Simulations For Frontline Providers Med-IQ, LLC Addressing Bone Manifestations of GD: The Latest 382,736.00 Evidence in Evaluation and Treatment Medscape LLC Updates and Perspectives in Diabetic Dyslipidemia: 246,500.00 2017 in Review Collaboration \3\ Medscape LLC Addressing Disease Burden in Asthma and Comorbidities: 400,000.00 From Pathophysiology to Targeted Treatments Medstar Georgetown University Multiple Sclerosis Patient Education Day 7,500.00 Hospital Mount Sinai School of Medicine The Icahn School of Medicine at Mount Sinai NP 75,000.00 Fellowship Program in Lysosomal Storage Disease National Association For Continuing Atopic Dermatitis: New Insights, New Therapies 150,000.00 Education National Committee for Quality A Patient-Centered Approach to Severe Asthma 232,325.00 Assurance NACCME, LLC Management: Embracing Diversity and Improving Collaboration \3\ Outcomes with Emerging Therapies NCCN Foundation NCCN Guidelines for Patients: Prostate Cancer 25,000.00 Nurse Practitioner Alternatives Advances In Multiple Sclerosis (AIMS) Primer: Third 59,150.00 Consortium of Multiple Sclerosis Edition Centers Nurse Practitioner Alternatives 1,800 SecondsTM in MS Management: An Online 92,000.00 Consortium of Multiple Sclerosis Educational Series for MS Clinicians Centers Oakstone Publishing, LLC PeerVoice A New Treatment Paradigm in Atopic Dermatitis: Expert 268,700.00 America Limited Insights on Incorporating Biologic Therapy Among Available Options Oakstone Publishing, LLC PeerVoice Optimizing Systemic Therapy for Atopic Dermatitis: 268,700.00 America Limited Practical Strategies to Ensure Patient Safety Oregon Health and Science University Annual OHSU Colloquium on Neuromuscular Disorders 5,000.00 PEERVOICE AMERICA LIMITED Oakstone ``Practical Strategies for Managing Inadequate 193,250.00 Publishing, LLC Responders to Atopic Dermatitis Treatment'' Collaboration \3\ Penn State College of Medicine Beyond the Guidelines: Investigator Perspectives on 100,000.00 Research To Practice Current Clinical Issues and Ongoing Research in the Management of Advanced Prostate Cancer PESG Lysosomal And Rare Disorders GRIDS2017: A workshop on immune aspects of Lysosomal 55,000.00 Research And Treatment Center Inc. Storage Disorders: From pathology to therapy Pharmacy Times Continuing Education A Specialty Pharmacy Update on PCSK9 Inhibitor Therapy 10,000.00 for Hypercholesterolemia Collaboration \3\ Pharmacy Times Continuing Education An American Journal of Managed Care Webinar: 75,255.00 Evaluating Novel Therapies for Atopic Dermatitis Physician's Education Resource, LLC Provider and Caregiver Connection--Getting Beneath the 167,850.00 Surface: Addressing Patient Concerns In Moderate to Severe Atopic Dermatitis Postgraduate Institute for Medicine Early Detection and New Approaches to the Management 150,000.00 Catamount Medical Education, LLC of Atopic Dermatitis in the Family Medicine Setting Collaboration3 Postgraduate Institute for Medicine The Role of Specialty Pharmacy and the Challenge of 150,000.00 Impact Education, LLC Managing Moderate-to-Severe Atopic Dermatitis Collaboration \3\ Postgraduate Institute for Medicine The Management of Atopic Dermatitis: Entering a New 200,000.00 Impact Education, LLC Paradigm Postgraduate Institute for Medicine Rheumatoid Arthritis Management Strategies: New 150,000.00 Impact Education, LLC Insights for Managed Care Postgraduate Institute for Medicine The Learning Pathway in Atopic Dermatitis: Optimizing 382,947.00 Robert Michael Educational Institute Management Approaches in Patients with Moderate-to- Collaboration \3\ LLC Severe Disease Potomac Center for Medical Education Targeting Improved Outcomes In Atopic Dermatitis: 449,955.00 Rockpointe Corporation Strategies for Achieving Personalized Treatment Goals Collaboration \3\ Potomac Center for Medical Education Achieving New Treatment Goals In Multiple Sclerosis: 176,000.00 Rockpointe Corporation Nurse Strategies for Initial Treatment Selection and Practitioner Alternatives Patient Engagement PRIME Education, LLC Aligning Managed Care Decision-Making with the Latest 272,543.00 Evidence for Targeted Asthma Treatment PRIME Education, LLC Navigating the Intersection of Uncontrolled Asthma and 354,188.00 Related Comorbidities: Implications of Novel Mechanisms of Action for Managed Care PRIME Education, LLC Advancing Specialty Pharmacy Decision-Making to 242,011.00 Optimize Therapy Selection and Access in Uncontrolled and Severe Asthma PRIME Education, LLC Solving the Problem of Choice in Treatment Decisions 182,535.00 for Patients with Rheumatoid Arthritis: Evidence- Based, Guideline-Directed, and Patient-Centered Strategies Pri-Med Institute, LLC Viscosupplementation for Osteoarthritis of the Knee: 149,499.92 Who, When, and How? Projects In Knowledge Asthma--Practical Applications from ATS 2018: A Video 50,000.00 Roundtable Rutgers, The State University of New Cognitive Dysfunction and Fatigue in Multiple 3,011.00 Jersey Sclerosis Sidney Kimmel Medical College at Thyroid Cancer 2017: New Advances in Diagnosis & 10,000.00 Thomas Jefferson Treatment Society for Inherited Metabolic 2017 North American Metabolic Academy 20,000.00 Disorders St. Joseph's Regional Medical Center Multiple Sclerosis: A Changing Landscape 1,300.00 The France Foundation Achieving Better Control of Severe Asthma: New 262,700.00 Understandings in Asthma Pathophysiology and Targeted Therapies The France Foundation Are You Ready? Recent Effective Atopic Dermatitis 240,720.00 Therapy Considerations The Regents of the University of Post Doc Fellowship 63,000.00 California--UCLA Division of Nephrology UC Regents Genetic Neuromuscular Diseases Fellowship 75,000.00 UMA Education, Inc. dba Global Beyond the Flare: A Practical Overview of the Newest 25,000.00 Education Group Tarsus Cardio dba Concepts in Atopic Dermatitis Pathogenesis and Collaboration \3\ South Beach Symposium Treatment UMA Education, Inc. dba Global 2018 Masters of Pediatric Dermatology Symposium 20,000.00 Education Group Tarsus Cardio Inc., Collaboration \3\ dba South Beach Symposium University Neurology, Inc. The 2017 New York State Multiple Sclerosis Consortium 5,000.00 (NYSMSC) Annual Professional Research and Education Meeting University of Alabama at Birmingham 2017 Fabry Fellowship 73,714.12 University of California, San Diego Challenges in Pompe 4,800.00 San Diego Neurology Society University of Colorado School of 87th Annual Meeting of the American Thyroid 50,000.00 Medicine American Thyroid Association Association University of Louisville School of Visiting Professor and Endocrine Grand Rounds 3,320.00 Medicine University of Louisville Global Skin Disease Education Foundation's 18th Annual Las 25,000.00 Academy for Medical Education Vegas Dermatology Seminar featuring the 14th Annual Collaboration \3\ Postgraduate Institute for Medicine Psoriasis Forum University of Louisville Postgraduate 17th Annual Caribbean Dermatology Symposium 50,000.00 Institute of Medicine Global Academy Collaboration \3\ for Medical Education University of Louisville Postgraduate Skin Disease Education Foundation's 42nd Annual Hawaii 50,000.00 Institute of Medicine Global Academy Dermatology Seminar Collaboration \3\ for Medical Education University of Massachusetts Medical New Frontiers and Pivotal Investigation-Based Advances 369,000.00 School CMEducation Resources in the Pathoimmunobiology and Management of Atopic Collaboration \3\ Dermatitis Vindico Medical Education, LLC Shutting Down MS: New Insights on Induction, 196,378.58 Escalation, Oral Agents, and Monitoring WEBMD Global Advancing the Care of Patients With Atopic Dermatitis- 301,000.00 International Perspectives for OUS MDS: An Initiative developed in partnership with the University of Sheffield Medical School, Dermatology Research ---------------------------------------------------------------------------------------------------------------- \1\ Applicant names are provided by the requestor. If applicants apply as a group for a single educational activity; all applicants may be not be identified above. The Company funds other educational activities (including fellowships and non-physician and patient education); all of which do not appear on this report, but appear on other reports on this site. \2\ ``Funding Amount'' is the amount that the Company funded during Q4, 2017 identified above based upon an agreement. Recipients are required to return any unused funds. Information on unused funds returned by the applicant on activities are not reported. ``Funding Amount'' does not include funds that may have been provided by other affiliated Sanofi Company Entities (e.g., Sanofi Pasteur). \3\ Collaboration (Shared) Funding--is the full amount of a grant funded under an agreement with Regeneron, some or all of which may be shared between the collaborating entities. Organization Name Amount Acid Maltase Deficiency Association INC. $5,000.00 Allergy & Asthma Network Mothers of Asthmatics, INC $50,000.00 Allergy & Asthma Network Mothers of Asthmatics, INC. $117,000.00 Allergy & Asthma Network Mothers of Asthmatics, INC. $25,000.00 Allergy & Asthma Network Mothers of Asthmatics, INC. $25,000.00 Allergy & Asthma Network Mothers of Asthmatics, INC. $25,000.00 Allergy & Asthma Network Mothers of Asthmatics, INC. $25,000.00 Allergy & Asthma Network Mothers of Asthmatics, INC. $60,000.00 Allergy & Asthma Network Mothers of Asthmatics, INC. $75,000.00 Alliance for the Adoption of Innovations in Medicine $50,000.00 American Association Of Kidney Patients Inc. $362,293.31 American Association Of Kidney Patients Inc. $10,000.00 American College of Allergy, Asthma & Immunology $6,000.00 American College of Allergy, Asthma & Immunology $30,000.00 American College of Allergy, Asthma & Immunology $70,000.00 American College of Allergy, Asthma & Immunology $100,000.00 American College of Allergy, Asthma & Immunology $60,000.00 American College of Allergy, Asthma & Immunology $55,000.00 American College of Allergy, Asthma & Immunology $95,000.00 American College of Allergy, Asthma & Immunology $165,000.00 American College of Allergy, Asthma & Immunology $35,000.00 American College of Allergy, Asthma & Immunology $30,000.00 American College of Allergy, Asthma & Immunology $150,000.00 American College of Allergy, Asthma & Immunology $175,000.00 American Kidney Fund Inc. $40,000.00 American Kidney Fund Inc. $10,000.00 APFED (American Partnership for Eosinophilic $15,000.00 Disorders) Arthritis Foundation $100,000.00 Arthritis Foundation $25,000.00 Arthritis Foundation $25,000.00 Arthritis Foundation $3,500.00 Arthritis Foundation $1,250.00 Arthritis Foundation $5,000.00 Arthritis Foundation $10,000.00 Arthritis Foundation $3,500.00 Arthritis Foundation $250,000.00 Arthritis Foundation $250,000.00 Arthritis Foundation $30,000.00 Arthritis Foundation $100,000.00 Arthritis Foundation $100,000.00 Arthritis Foundation Inc. $2,500.00 Arthritis Foundation of NENY $5,000.00 Association For Glycogen Storage Disease $3,000.00 Asthma and Allergy Foundation of America $150,000.00 Asthma and Allergy Foundation of America $24,200.00 Asthma and Allergy Foundation of America $50,000.00 Asthma and Allergy Foundation of America $75,000.00 Asthma and Allergy Foundation of America $100,000.00 Asthma and Allergy Foundation of America, New England $20,000.00 Chapter Aubrey Rose Foundation $25,000.00 Barbara Ann Karmanos Cancer Institute $10,000.00 Be The Match Foundation $40,000.00 Berkshire Resource Project $1,500.00 Berkshire Resource Project $1,500.00 Beyond the Diagnosis $10,000.00 Can Do Multiple Sclerosis $8,000.00 Can Do Multiple Sclerosis $40,000.00 Can Do Multiple Sclerosis $26,000.00 Can Do Multiple Sclerosis $10,000.00 Can Do Multiple Sclerosis $10,000.00 Can Do Multiple Sclerosis $20,000.00 Can Do Multiple Sclerosis $20,000.00 Can Do Multiple Sclerosis $30,000.00 Can Do Multiple Sclerosis $40,000.00 Can Do Multiple Sclerosis $70,000.00 Can Do Multiple Sclerosis $30,000.00 Community Oncology Alliance $75,000.00 CrowdCare Foundation $45,000.00 Cure GM1 Incorporated $5,000.00 Cure GM1 Incorporated $5,000.00 Cystic Fibrosis Foundation $10,000.00 EveryLife Foundation for Rare Diseases $10,000.00 EveryLife Foundation for Rare Diseases $30,000.00 EveryLife Foundation for Rare Diseases $5,000.00 EveryLife Foundation for Rare Diseases $30,000.00 EveryLife Foundation for Rare Diseases $15,000.00 EveryLife Foundation for Rare Diseases $25,000.00 EveryLife Foundation for Rare Diseases $20,000.00 Fabry Support & Information Group $22,000.00 Fabry Support & Information Group $1,500.00 Fabry Support & Information Group $50,000.00 Fabry Support & Information Group $30,000.00 Fabry Support & Information Group $100,000.00 Florida Hemophilia Association $3,000.00 Foundation Fighting Blindness Inc. $5,000.00 Fundacion de Esclerosis Multiple de Puerto Rico $15,000.00 Global Alliance for Patient Access $115,000.00 Global Alliance for Patient Access $30,000.00 Global Healthy Living Foundation, Inc. $100,000.00 Global Healthy Living Foundation, Inc. $50,000.00 Global Parents for Eczema Research, a project of $47,438.00 Heluna Health Great Lakes Hemophilia Foundation Inc. $2,500.00 Hemophilia Foundation of Northern California $5,000.00 Hemophilia of Iowa $1,500.00 Hemophilia of Iowa $1,000.00 Hemophilia of North Carolina $5,000.00 Hermansky-Pudlak Syndrome Network $24,935.00 Holy Name Health Care MS Center $2,500.00 Holy Name Health Care MS Center $2,500.00 Hope for Hemophilia $15,000.00 Hope for Hemophilia $15,000.00 International Myeloma Foundation $75,000.00 International Myeloma Foundation $50,000.00 International Myeloma Foundation $75,000.00 International Society For Mannosidosis & Related $30,000.00 Disease Inc. Kessler Foundation $5,000.00 Leukemia & Lymphoma Society--MA Chapter $20,000.00 Light of Life Foundation $5,000.00 Little Miss Hannah Foundation $1,000.00 Lone Star Chapter of the National Hemophilia $15,000.00 Foundation Lymphoma Research Foundation $20,000.00 March of Dimes Foundation $10,000.00 March of Dimes Foundation $15,000.00 Mercy Foundation $20,000.00 Mid America MS Achievement Center $5,000.00 Mid America MS Achievement Center $5,000.00 MLD Foundation $12,000.00 MLD Foundation $12,000.00 MS Bright Spots of Hope $2,500.00 MS Cure Fund $3,000.00 MS Cure Fund $5,250.00 MS Cure Fund $2,500.00 MS Dream Center--RI, Inc. $3,000.00 MS HOPE FOR A CURE INC. $10,000.00 MS Views and News $25,000.00 MS Views and News $50,000.00 MS Views and News $30,000.00 MS Views and News $30,000.00 MS Views and News $10,000.00 MS Views and News $40,000.00 MS Views and News $25,000.00 MSWorld, Inc. $4,000.00 Multiple Myeloma Cure Seeker Society $5,000.00 Multiple Sclerosis Association of America $200,000.00 Multiple Sclerosis Association of America $30,000.00 Multiple Sclerosis Association of America $25,000.00 Multiple Sclerosis Association of America $50,000.00 Multiple Sclerosis Association of America $50,000.00 Multiple Sclerosis Association of America $46,031.00 Multiple Sclerosis Center of Georgia $10,000.00 Multiple Sclerosis Center of Georgia $7,000.00 Multiple Sclerosis Foundation $30,000.00 Multiple Sclerosis Foundation $20,000.00 Multiple Sclerosis Foundation $50,000.00 Multiple Sclerosis Resources of Central New York, Inc. $7,500.00 Muscular Dystrophy Association $20,000.00 Muscular Dystrophy Association $430,000.00 National Bone Marrow Transplant Link $3,000.00 National Eczema Association $100,000.00 National Eczema Association $85,000.00 National Eczema Association $100,000.00 National Eczema Association $75,000.00 National Eczema Association $100,000.00 National Fabry Disease Foundation $100,000.00 National Fabry Disease Foundation $100,000.00 National Fabry Disease Foundation $40,000.00 National Gaucher Foundation $1,500,000.00 National Gaucher Foundation $650,000.00 National Gaucher Foundation $200,000.00 National Gaucher Foundation $1,900,000.00 National Hemophilia Foundation $37,500.00 National Hemophilia Foundation $100,000.00 National Hemophilia Foundation $9,479.00 National Kidney Foundation $3,700.00 National Kidney Foundation $10,000.00 National Kidney Foundation $10,000.00 National MPS Society $500.00 National MPS Society $20,000.00 National MPS Society $100,000.00 National MS Society $5,000.00 National Multiple Sclerosis Society $780,000.00 National Multiple Sclerosis Society $65,000.00 National Multiple Sclerosis Society $15,000.00 National Multiple Sclerosis Society $2,500.00 National Multiple Sclerosis Society $15,000.00 National Multiple Sclerosis Society $750,000.00 National Multiple Sclerosis Society $150,000.00 National Multiple Sclerosis Society New York City $2,500.00 Chapter National Multiple Sclerosis Society New York City $1,100.00 Chapter National Multiple Sclerosis Society New York City $15,000.00 Chapter National Multiple Sclerosis Society New York City $122,100.00 Chapter National Multiple Sclerosis Society New York City $5,000.00 Chapter National Multiple Sclerosis Society New York City $1,250.00 Chapter National Multiple Sclerosis Society New York City $300.00 Chapter National Multiple Sclerosis Society New York City $1,000.00 Chapter National Multiple Sclerosis Society New York City $5,000.00 Chapter National Multiple Sclerosis Society New York City $5,000.00 Chapter National Niemann-Pick Disease Foundation $40,000.00 National Organization for Rare Disorders, Inc. $50,000.00 National Organization for Rare Disorders, Inc. $5,000.00 National Organization for Rare Disorders, Inc. $25,000.00 National Organization for Rare Disorders, Inc. $100,000.00 National Organization for Rare Disorders, Inc. $75,000.00 National Organization for Rare Disorders, Inc. $50,000.00 National Tay-Sachs & Allied Diseases Association, Inc. $20,000.00 National Tay-Sachs & Allied Diseases Association, Inc. $10,000.00 National Tay-Sachs & Allied Diseases Association, Inc. $10,000.00 New England Hemophilia Association $5,000.00 New England Hemophilia Association $10,000.00 New England Hemophilia Association $2,500.00 New England Hemophilia Association $7,500.00 Next Step Fund Inc. $10,000.00 OhioHealth Corporation $25,000.00 Osteogenesis Imperfecta Foundation $5,000.00 Patient Access Network Foundation $300,000.00 Patient Empowerment Network $20,000.00 Patient Empowerment Network $20,000.00 Patient Services, Inc. $662,500.00 Patient Services, Inc. $2,381,250.00 Patient Services, Inc. $4,797,500.00 Patient Services, Inc. $1,418,750.00 Patient Services, Inc. $1,365,000.00 PKD Foundation $50,000.00 PKD Foundation $20,000.00 PKD Foundation $25,000.00 Prostate Cancer Foundation $300,000.00 Prostate Health Education Network Inc. $20,000.00 Quinn Madeleine Inc. $5,000.00 Rare Disease United Foundation $15,000.00 Rare New England, INC. $4,000.00 Rare New England, INC. $4,000.00 Rare New England, INC. $4,000.00 Rocky Mountain Multiple Sclerosis Center $2,500.00 Rocky Mountain Multiple Sclerosis Center $5,000.00 Rocky Mountain Multiple Sclerosis Center $5,000.00 Rocky Mountain Multiple Sclerosis Center $2,500.00 Rocky Mountain Multiple Sclerosis Center $3,000.00 Sofia Sees Hope $22,000.00 Swiss Hemophilia Society (Schweizerische Hemophilie $2,600.00 Gesellschaft) The Assistance Fund, Inc. $10,000,000.00 The Leukemia & Lymphoma Society Eastern PA Chapter $10,000.00 ThyCa: Thyroid Cancer Survivors' Association, Inc. $5,000.00 ThyCa: Thyroid Cancer Survivors' Association, Inc. $3,000.00 ThyCa: Thyroid Cancer Survivors' Association, Inc. $5,000.00 ThyCa: Thyroid Cancer Survivors' Association, Inc. $10,000.00 Tisch Multiple Sclerosis Research Center of New York, $15,000.00 Inc. Tisch Multiple Sclerosis Research Center of New York, $2,500.00 Inc. Transplant Life Foundation $12,000.00 Tri-State Multiple Sclerosis Association $2,500.00 United Pompe Foundation $50,000.00 United Pompe Foundation $42,500.00 United Pompe Foundation $30,000.00 United States Bone and Joint Initiative, NFP $80,000.00 United States Bone and Joint Initiative, NFP $30,000.00 United States Bone and Joint Initiative, NFP $25,000.00 University of Minnesota Foundation $5,000.00 Us TOO International $2,500.00 Us TOO International $30,000.00 Wylder Nation Foundation $5,000.00 Wylder Nation Foundation $15,000.00 Program/Event PCMA of Texas's Pull Telehealth 2018 Patient Awareness for Pompe Program Understanding Severe 2018 USAsthma Summit Corporate Council 2018 Asthma Program 2018 Allergy & Asthma 2018 Asthma Bloggers Understanding Severe Awareness Day Conference Asthma Guide Webinars on Medical Education Education Project Dermatological Conditions in the Workplace Eczema Online Program Patient Awareness Patient Awareness Program Program Fellow-in-Training Severe Atopic 2018 Corporate Council Travel Scholarships Dermatitis Toolkit Membership Program Biologics Education Severe Asthma Allergist Webinar Education Program and Patient Education Program Severe Asthma Patient Practice Management Educational Tools for Education Center: Expansion and Allergists and Enhancement Patient Education Campaign Patient Education Proposal Request in Annual Patient Program Support of 360 Degrees Education Conference of Care Patient Voice Access Arthritis Foundation 2018 Arthritis Project Patient Engagement at Foundation Conference ACR of Champions 2018 Bone Bash Silver Ball Fundraiser Evening of Honors Fundraiser Fundraiser Freedom of Movement San Francisco Bone Bash 2018 Jingle Bell Run Fundraiser Fundraiser Walk to Cure Arthritis Arthritis Industry Patient Awareness Forum (AIF) Program Patient Education and 2018 Bone Bash Albany Commitment to a Awareness Program Fundraiser Cure Fundraiser Annual GSD Conference Patient Education Patient Access Program Program My Life With AD AAFA's Patient Support My Kids' Life With Center Asthma Be Smart and Breathe Medical Resources for 8th Annual Prostate Easy Patient Education Children: An Cancer Symposium Invaluable Database Be The Match 2018 Patient Education and Patient Education National Walk+Run Awareness Program Program Series Operating Support Patient Awareness 2019 SKI for MS Program 2019 JUMPSTART Program 2018 MS Global Patient 9th Annual Can Do Exhibits Programs Month 2018 Young 2018 JUMPSTART Program 2018 Online Programs Professionals Program Exhibition Sponsorship 2018 CAN DO Program 2018 JUMPSTART Program 2018 Can Do On Demand 2018 COA Corporate Patient Awareness 2nd GM1 Research Sponsorship Program Symposium TORCH award donation Fundraiser event Patient Awareness Program RareVoice Awards Rare Disease Scientific RARE on the Road Workshop Leadership Series Patient Awareness Rare Disease Week Community Congress Program Sponsorship FSIG Patient Meetings 2018 Fun Run/Walk 2018 FSIG Expert Fabry Conference Patient Assistance Operating Support 35th Annual Florida Program Bleeding Disorders Conference Boston VisionWalk Managing MS: A European RA patient multidisciplinary online program approach European Alliance for Patient Education and 50-State Network Patient Access RA Awareness Program Patient Advocacy Stakeholders Workshop Assessing and 2018 Wisconsin Bleeding BLeaders Communicating the Disorders Conference Impact of AD on Patients and Families Annual Meeting Teen Program Family Education Sponsorship Program Research Program 2018 MS Awards 21st Annual Spring Reception Fling for MS Superhero Run/Walk-- 2018 Superhero Hope Run/ Long Term Care Covington Walk--Wichita Survivors Initiative 2018 IMF Patient IMF 9th Annual 6th Glycoproteinoses Patient and Family International Myeloma International Seminars and Regional Working Group Summit Conference--Atlanta-- Community Workshops USA Kessler Foundation's Light The Night Boston Light of Life 2018 Stroll 'N Roll Foundation 2018 Walk Patient Activities 3rd Annual Vegas Cares Texas Bleeding Research Program About Rare Kids 5K Disorders Conference 2018 Fundraising Event Boston March for Babies Multiple Sclerosis Achievement Center Wellness Education programs Eat Bid Laugh 7 Program Race to Nowhere 2018 RUSP Roundtable Program RUSP Roundtable Program MS Bright Spots Evening 6th ANNUAL MS ADAPTIVE of Hope SKI DAY--THRIVING BEYOND MS! Relapse Management and MS ALPINE ADVENTURES Exhibit Sponsorship Rehabilitation Program 2018 ADAPTIVE SKI DAY 2018 MS Hope Day Patient Education and Patient Education and Awareness Program Awareness Program Patient Education and Patient Education and 2018 Champions Awareness Program Awareness Program Tackling MS Awards Dinner Patient Education and Patient Education and 2018 ``MSWorld Talks'' Awareness Program Awareness Program Cleveland Clinic: Display Table 2018 Defeat Multiple Patient Assistance A Better Understanding Myeloma Run/Walk Program of MS within the Hispanic Community Patient Education and 2018 Multiple Sclerosis MS Awareness Month Awareness Program Summit: A Community 2018 Conference and Exposition 2018 Needs Assessment MS Fest for Patients Health, Hope & Hops MS Focus' Homecare MS Focus' Assistive National MS Education Assistance Grant Technology Program and Awareness Month Program 2018 2018 Mission Steps Walk Congress Sponsorship Community Education and MS Awareness Days and Engagement Support Resource Guide of Eczema Awareness Month- The Face of Atopic Helpful Organizations Unhide Eczema Campaign Dermatitis in America Eczema Expo '18 Atopic Dermatitis Teen Educational Webcasts Commitment Campaign for Patients & Caregivers Operating Support 2018 Fabry Community Community support Support and Education programs programs Patient Assistance Patient Education and Patient Education and Program Awareness Program Awareness Program Patient Assistance NHF 2018 Bleeding UNITE for Bleeding Program Disorders Conference Disorders National Walk 2018 NHF Bleeding Disorders Congress Sponsorship New York City Kidney Conference 2018 Walk The Big Ask The Big In-Kind Donation National MPS Society Give National Run Program 2018--15th Bike MS: City to Shore National sponsorship International Ride of Walk MS and local Symposium on MPS and sponsorship of select Related Diseases Bike MS events MS Breakthroughs 2018 National MS Women on the Move-- Program Society Leadership Pittsburgh Conference Everyday Matters: National MS Society Fellowship Program Living Your Best Life National Event with MS Sponsorship Knoxville Fall Crush 40th Annual Ambassadors Mood Changes In MS Fundraiser Alliance Industry Forum On the Move Luncheon-- Women on the Move 2018 New Orleans Luncheon and Fashion Show--Cincinnati Women On the Move-- 2018 On the Move On The Move Luncheon- Washington, D.C. Luncheon--St Louis Houston 2017 On The Move Patient Education and Patient Assistance Luncheon--Dallas TXH Awareness Program Program Running for Rare 2018 Corporate Council Patient Education and Membership--Corporate Awareness Program Product Member 2018 Rare Diseases and 2018 Rare Impact Awards Imagine & Believe Orphan Product Program Breakthrough Summit Voices of 40th Annual Family Congress Sponsorship Determination, An Conference Evening to Benefit NTSAD Family Camp Massachusetts Advocacy New England Hemophilia Days Association 9th Annual Walk Face Forward OhioHealth Multiple Conference Sponsorship Campference and Year- Sclerosis Wellness Round Programming for Program Youth With Rare Genetic Disorders Patient Assistance Multiple Myeloma 2018 Myeloma Patient Program Community Meetings Cafe Patient Assistance Patient Assistance Patient Assistance Program Program Program Patient Assistance Patient Assistance Walk for PKD Program Program 2018 Boston Walk for 2018 PKD Connect 25th Annual Scientific PKD National Conference Retreat PHEN Rally Against TORCH award donation Beyond the Diagnosis Prostate Cancer Rare New England Inc. RNE Honors Rare Disease Patient Education and Day Speakers Series Awareness Program 2019 2018 RMMSC Annual 2018 MS4MS (Multiple Rocky Mountain MS Fundraiser Summits for MS) Center's Spring Education Summit 2018 Conversations on 2018 Webinar Series LCA and IRD Community MS Outreach and Education 70th NHF Bleeding Patient Assistance LLS Light The Night Disorders Conference Program Events Website Update Project Congress Sponsorship 21st International Thyroid Cancer Survivors' Conference Patient Education and Patient Education and 2018 Future Without MS Awareness Program Awareness Program Fundraiser Donate Life Transplant Autumn Walks Fiscal Year 2018 Games Patient Meeting Patient Meeting Experts in Arthritis Program Access Program Corporate Sponsorship Marrow on the Move 14th Annual SEA Blue Us TOO Prostate Cancer TORCH award donation Prostate Cancer Walk & Regional Educational Run Symposiums 5th Annual Living Like a Warrior Gala Independent Medical Education Grants 1st Jan 2018-31th Mar 2018 Sanofi US and its affiliate Genzyme Corporation are committed to supporting independent medical education activities in therapeutic areas in which the Company is involved, for healthcare professionals, patients, and consumers to improve patient care and health outcomes in therapeutic areas in which the Company is engaged. Sanofi US and Genzyme Corporation are part of the Sanofi Group, a global pharmaceutical company. ---------------------------------------------------------------------------------------------------------------- Funding Amount Recipient Name(s) \1\ Activity Title ($) \2\ ---------------------------------------------------------------------------------------------------------------- University of Kansas Continuing 2017 Muscle Study Group Scientific annual Meeting-- 25,000 Education & Professional Development Neuromuscular Therapeutics: Bench to Bedside and Beyond National Jewish Health PVI Peerview PeerView inPlay and inClinic: ``Optimizing Asthma 209,000 institute for Medical Education Inc. Control Through Accurate Identification, Evidence- Based Management and Targeted Therapeutic Options'' Aventura Hospital Miami Thyroid Oncology Symposium 10,000 AcademicCME, LLC. ASCO GU 2018: A Clinical Analysis of Optimal 82,300 Therapeutics to Improve Outcomes in Patients with Prostate Cancer The Medical College of Wisconsin, PeerView Live at BMT 2018, ``Integrated Myeloma 88,555 Inc. PVI, PeerView Institute for Management & Enhanced Patient Outcomes: The Medical Education, Inc. Conjunction of Novel Therapeutic Platforms, Innovative Agents, and Stem Cell Transplant'' American Society of Transplant 18th Annual State of the Art Winter Symposium The 75,000 Surgeons Future Is Now: Saving More Lives Through Transplantation The Medical College of Wisconsin, Optimal Use of Stem Cell Mobilization in Patients with 305,000 Inc. Carden Jennings Publishing Multiple Myeloma and Non-Hodgkin's Lymphoma Medical Learning Institute PVI, PeerView inReview, ``Assessing the Potential Impact of 104,250 PeerView Institute for Medical New Consensus Recommendations and Ongoing Clinical Learning Trials of Emerging Therapies on the Diagnosis and Treatment of Acid Sphingolmyelinase Deficiency'' National Society of Genetic New Lysosomal Storage Disease Healthcare Advocate 42,637 Counselors (NSGC) Workshop 2018 American Society of Clinical 2018 Genitourinary (GU) Cancers Symposium: Translating 30,000 Oncology, Inc. Conquer Cancer Evidence to Multidisciplinary Care Foundation of the American Society of Clinical Oncology American Association of Clinical Advances in Medical & Surgical Management of Thyroid 15,000 Endocrinologists Cancer ScientiaCME LLC Atopic Dermatitis (AD): Best Practices, Barriers to 19,100 Care, and Emerging Therapies in Medication Management Potomac Center for Medical Education Risk-Benefit Analysis and Personalized Treatment in 100,000 Rockpointe Corporation Multiple Sclerosis: Basing Treatment Goals on the Latest Evidence Elsevier Office of Continuing Medical Moving from Treating Atopic Dermatitis Symptoms to 165,000 Education ASiM CE, LLC Treating Underlying Pathology University of Cincinnati Advances in MauiDerm 2018 50,000 Cosmetics and Medical Dermatology Postgraduate Institute for Medicine The Rheumatoid Arthritis Vital Education Initiative: 264,800 New Horizons in Therapeutic Options (RAVE: New Horizons) American Society for Blood and Marrow American Society for Blood and Marrow Transplantation 65,000 Transplantation New Investigator Award UT Southwestern Medical Center 40th Annual Carrell-Krusen Neuromuscular Symposium 5,000 Regents of the University of 6th Annual UC San Diego Essentials and Advances in 5,000 California Apheresis Physicians' Education Resource Multiple Sclerosis: A Treatment Paradigm Shift when 85,100 Time is Brain Physicians' Education Resource, LLC 2018 New York GUTTM: 11th Annual Interdisciplinary 50,000 (PER) Prostate Cancer Congress National Comprehensive Cancer Network NCCN 23rd Annual Conference: Improving the Quality, 25,000 Effectiveness, and Efficiency of Cancer CareTM UNTHSC Overcoming Persistent Barriers to Effective Management 72,500 of Atopic Dermatitis Cleveland Clinic Educational 2018 Nephrology Update 10,000 Foundation Medical Learning Institute, Inc. PVI, PeerView in Session, ``New Developments in Allergic 168,730 PeerView Institute for Medical and Inflammatory Diseases: Clinical Updates From San Education, Inc. Diego and Orlando'' Penn State College of Medicine PVI, Science and Stories: Navigating the Prostate Cancer 90,000 PeerView Institute for Medical Landscape: Urologists at the Intersection of Emerging Education Inc. Evidence and Patient Centric Care UMA Education Inc., dba Global Cutting Edge of Transplantation 2018: Breaking through 40,000 Education Group American Society of Regulatory Barriers to Unleash Transplant Innovation Transplantation to Success American College of Rheumatology 2018 ACR Rheumatology Courses 75,000 PRIME Education, LLC Global Perspectives on Current and Emerging Biologic 151,341 Therapies for Rheumatoid Arthritis The Medical College of Wisconsin, The 28th Annual International Prostate Cancer Update 10,000 Inc. Carden Jennings Publishing Co., (IPCU 28) Ltd. NYU Post-Graduate Medical School NYU Langone Seminar in Advanced Rheumatology 20,000 AcademicCME, LLC. Individualizing Treatment Plans to Reduce Disease 75,000 Activity in Patients with Rheumatoid Arthritis Physicians' Education Resource, LLC Medical Crossfire: Personalizing Care for Multiple 75,000 (PER) Myeloma Patients: Current and Future Sequencing Strategies American College of Surgeons The changing face of thyroid cancer management for 40,900 surgeons: real-life applications of the new ATA guidelines Penn State College of Medicine PVI, PeerView Live at ASCO 2018: ``How I Think, How I 75,000 PeerView Institute for Medical Treat: A Personal Look at Innovative Therapy and Education, Inc. Meeting Patient Needs in Multiple Myeloma'' UMA Education Inc., LLC dba: Global Evolving Management Strategies for Moderate-to-Severe 346,647 Education Group (GLOBAL) Atopic Dermatitis: Looking Beyond Barriers to Optimized Therapy Physicians' Education Resource, LLC Advances InT Supportive Care: An Onco-Nurses Guide to 50,000 (PER) Managing Cancer Treatment-Related Toxicities National Association of Managed Care Exploring the Challenges of Severe Asthma: 45,000 Physicians Implementing Personalized Treatment Plans for Improved Patient Outcomes National Association for Continuing Conversations in Dermatology The Evolving Paradigm in 59,000 Education Atopic Dermatitis: Integrating Evolving Treatments to Improve Outcomes Eastern Virginia Medical School Multiple Sclerosis Symposium 2018 5,000 University of Kansas Medical Center Neuromuscular Review Course 25,000 American Academy of Pas Medical Moving Toward Improved Outcomes in MS: How PAs Can 50,000 Logix, LLC Make a Difference Med-IQ, LLC Preventing Tumor Lysis Syndrome: Risk Assessment and 75,000 Appropriate Prophylaxis Cleveland Clinic Educational Cleveland Clinic Neurological Institute Summit 2018: 50,000 Foundation MS Treatment Strategies Johns Hopkins University School of 14th Annual Advances in the Diagnosis and Treatment of 30,000 Medicine the Rheumatic Diseases National Association of Managed Care Implementing Newer Biologic Therapies to Improve 57,000 Physicians Economic and Clinical Outcomes in Patients with Moderate to Severe Atopic Dermatitis Annenberg Center for Health Sciences Master Class for Oncologists 30,000 at Eisenhower Dana Farber Cancer Institute Elsevier Office of Continuing Medical Rising to the Challenge: Diagnosis and Optimal 124,000 Education ASiM CE LLC Dannemiller Management of Atopic Dermatitis in the Primary Care Setting National Association of Managed Care Novel Treatment Advances and Approaches in Rheumatoid 45,000 Physicians Arthritis: Personalizing Therapy for Improved Clinical and Economic Outcomes National Kidney Foundation Managing the Life-Long Impact of Fabry Disease 265,995 Annenberg Center for Health Sciences Optimal Treatment sequencing in Metastatic Castration- 65,000 at Eisenhower PlatformQ Health Resistant Prostat Cancer: Expert Analysis through Education, LLC Case Studies Michael J Fox Foundation MDS-PAS Movement Disorders School for Neurology 20,000 Residents Penn State College of Medicine PVI, Science and Stories at ASCO 2018: Making an Impact in 100,000 PeerView Institute for Medical Prostate Cancer--Using Expert Experience and Evidence Education, Inc. to Personalize the Complex Treatment Landscape Purdue University Clinical Care Advancing Care in Prostate Cancer: Aligning Your 80,000 Options, LLC Practice With Rapidly Evolving Standards of Care Throughout the Disease Continuum Continuing Education Alliance 2018 PCE Oncology Symposia Series Segment: Sequencing 125,000 Therapy in Patients with Castration-Resistant Prostate Cancer University of Chicago At the Forefront of Hepatology 5,000 National Association of Managed Care The Value of Personalized Treatment Sequencing for 45,000 Physicians Castration-Resistant Prostate Cancer Vindico Medical Education, LLC Immunology Bootcamp 100,000 American Urological Association 2018 Evidence-based Clinical Management of Advanced 100,000 and Castration-Resistant Prostate Cancer International Transplant Nurses European Transplant Nursing Symposium 10,000 Society UMA Education Inc., dba Global R.A.P.I.D.--Rheumatoid Arthritis: A Primary Care 200,000 Education Group FACTORx MedEd Initiative for Improved Diagnosis and Outcomes Consulting Improve CME, LLC NACE Pri- Med Indegene, Inc. Postgraduate Institute for Medicine The Learning Pathway in Atopic Dermatitis: Maximizing 362,310 Positive Outcomes for Your Patients American Urological Association AUA 2018 Highlights in Advanced and Castration- 80,000 Resistant Prostate Cancer PESI Inc. 15th Annual World Congress on Insulin Resistance, 50,000 Diabetes & Cardiovascular Disease Horizon CME Improving the Quality of Care in Patients with 237,900 Diabetes through a Simulated QI Experience Joslin Diabetes Center Long-acting Insulins in Treatment of Type 2 Diabetes: 324,500 Aligning Provider and Patient Perspectives to Address Therapeutic Barriers Boston University School of Medicine Balancing Glycemic Control and Hypoglycemia in T2DM: 435,000 Practicing Clinicians Exchange (PCE) the Role of long-acting Basal Insulin Analogues Physicians' Education Resource Physiologic Insulin Replacement: Practical Strategies 105,650 for Insulin Initiation and Titration of Long-Acting Insulins University of Massachusetts Medical The Foundational role of Physiologic, long-acting 341,000 School CMEducation Resources Basal Insulin: Optimizing the safety-efficacy equation in vulnerable patients with T2D Postgraduate Institute for Medicine Targeting diabetic patients for Physiologic, long- 496,200 CMEducation Resources acting Basal Insulin therapy--A best practice roadmap to clinical success The Endocrine Society Institute for Diabetes Masters Series 2018: Getting to the heart of 249,885 Medical and Nursing Education, Inc. the matter: Multidisciplinary perspectives on patient- centered care in T2DM American Association of Diabetes Leveraging CDEs to Improve Individualized Management 1,024,440 Educators of T2D: Focus on Injectable Therapies Pharmacy Times Continuing Education An American Journal of Managed Care Medical Crossfire: 202,150 Evaluating New Generation Basal Insulin Therapy American Association of Nurse The I's Have It: Improving Insulin Initiation Inertia 358,557 Practitioners A Nurse Practitioner-Led Quality Initiative Pri-Med Institute, LLC Newer Long-acting Insulins: A Physiologic Approach to 721,504 Glucose Control National Association for Continuing Clinical Updates for NPs and PAs: 2018--Advances in 244,585 Education Insulin Therapy: Another Step Closer to a More Physiological Strategy Institute for Medical and Nursing AAFP 2018: Building Basal Knowledge: Establishing a 374,867 Education, Inc. Solid Foundation for Using New Options in Basal Insulin for T2DM NACCME, LLC Incorporating Long-Acting Insulin Therapy into the 180,565 Physiologic Approach to Diabetes Management Postgraduate Institute for Medicine Multi-Mechanistic, Insulin-Based Approaches for 347,000 CMEducation Resources Achieving HA1c/PPG Targets and Optimizing Safety in Challenging Patients with T2D Pharmacy Times Continuing Education Emerging Strategies for the Safe and Effective 81,303 Treatment of Uncontrolled Diabetes: The Application of Fixed Ratio Combination Insulin/GLP-1 RA Options Boston University School of Medicine Type 2 Diabetes: New Treatment Combinations for Early 870,000 Practicing Clinicians Exchange and Aggressive Glucose Control Postgraduate Institute for Medicine Complementary insulin-based approaches for achieving 935,000 CMEducation Resources HA1c/PPG targets and optimizing safety in patients with T2D: A best practice roadmap American Academy of PAs Achieving Quality Measures in T2DM: Addressing 199,600 Clinical Inertia and Patient Needs with Complementary Insulin-Based Therapies National Association for Continuing Clinical Updates for NPs and PAs: 2018--Combination 244,585 Education Basal Insulin and GLP-1 RA Therapy: A Physiologic Approach to Diabetes Care North Carolina Academy of Family Ready, set, action: An intervention to combat clinical 372,477 Physicians Med-IQ, LLC inertia and reduce prolonged hyperglycemia in T2DM Pharmacy Times Continuing Education The Advent of Insulin/GLP-1 RA Fixed-Ratio Agents for 129,020 Uncontrolled Diabetes: Moving Past the Barriers of Clinical Inertia Pri-Med Institute, LLC Treatment Intensification in T2DM: A Pathophysiologic 721,504 Approach to Combining GLP-1 Receptor Agonists with Basal Insulin American Association of Clinical Endocrine University: Lipids Module 4,000 Endocrinologists Elsevier Office of Continuing Medical Raising the Bar by Lowering the Target: Integrating 419,083 Education Integritas Communications PCSK9 Inhibitors into Hypercholesterolemia Management University of Tennessee College of Breaking Barriers to Diabetes Control with GLP-1RA/ 165,000 Pharmacy Insulin Combination Agents: Opportunities for the Community Pharmacist American Association of Nurse Advances in Diabetes Management: Titratable Fixed- 235,873 Practitioners Ratio Combination Therapy and its Role in T2DM Treatment University of California, San Diego Comparing and Contrasting Basal Insulin Strategies in 481,775 Type 1 and Type 2 Diabetes University of Massachusetts Medical The Mechanistic and Therapeutic Rationale for Dual 342,750 School CMEducation Resources SGLT1/2 Inhibition in Adults with Type 1 Diabetes Collaboration \4\ American Association of Clinical AACE 2018--Reflecting on the Data Pool: Emerging Roles 357,151 Endocrinologists Institute for for SGLT1 and SGLT2 Inhibition in T1DM Collaboration \4\ Medical and Nursing Education, Inc. American Association of Diabetes Reducing Glycemic Variability in Type 1 Diabetes: An 333,715 Educators E&S MedEd Group, Inc. Exploration of Non-Insulin Treatment Options Collaboration \4\ Medscape LLC Maximizing Medical Management of Knee Osteoarthritis: 174,500 Use of Injectable Therapy Oakstone Publishing, LLC. PeerVoice Reducing Cardiovascular Risk in Patients With 374,288 America Limited Dyslipidemia: What Do We Know Now? (And What Should Collaboration \3\ We Do About It?) Pharmacy Times Continuing Education Managing Hypercholesterolemia: Clinical Updates for 85,201 Specialty Pharmacists on PCSK9 Inhibitor Therapy Collaboration \3\ Postgraduate Institute for Medicine The Landmark Evidence and Clinical Rationale for PCSK9 486,800 CMEducation Resources Inhibition in the diabetic patient Collaboration \3\ Preventive Cardiovascular Nurses 2018 PCNA Dyslipidemia Campaign 60,000 Association Collaboration \3\ Oakstone Publishing, LLC. PeerVoice Modern Management of Lipid-Related Cardiovascular Risk 375,000 America Limited in Patients With Dyslipidemia Collaboration \3\ UMA Education, Inc. dba Global Mastering the Prior Authorization Process to Meet 275,000 Education Group Patient Needs Collaboration \3\ ---------------------------------------------------------------------------------------------------------------- \1\ Applicant names are provided by the requestor. If applicants apply as a group for a single educational activity; all applicants may be not be identified above. The Company funds other educational activities (including fellowships and non-physician and patient education); all of which do not appear on this report, but appear on other reports on this site. \2\ ``Funding Amount'' is the amount that the Company funded during Q1, 2018 identified above based upon an agreement. Recipients are required to return any unused funds. Information on unused funds returned by the applicant on activities are not reported. "Funding Amount" does not include funds that may have been provided by other affiliated Sanofi Company Entities (e.g., Sanofi Pasteur). \3\ Collaboration (Shared) Funding--is the full amount of a grant funded under an agreement with Regeneron, some or all of which may be shared between the collaborating entities. \4\ Collaboration (Shared) Funding--is the full amount of a grant funded under an agreement with Lexicon, some or all of which may be shared between the collaborating entities. Independent Medical Education Grants 1st April 2018-30th June 2018 Sanofi US and its affiliate Genzyme Corporation are committed to supporting independent medical education activities in therapeutic areas in which the Company is involved, for healthcare professionals, patients, and consumers to improve patient care and health outcomes in therapeutic areas in which the Company is engaged. Sanofi US and Genzyme Corporation are part of the Sanofi Group, a global pharmaceutical company. ---------------------------------------------------------------------------------------------------------------- Funding Amount Recipient Name(s) \1\ Activity Title ($) \2\ ---------------------------------------------------------------------------------------------------------------- Med-IQ, Inc. Getting Social About Multiple Sclerosis: Tools for 75,000 Newly Diagnosed Patients and Their Care Teams National Association of Managed Care Building a Better Understanding in Asthma Management: 57,000 Physicians Best Practices for Treatment and Control Excel Continuing Education Exploring the Genetics and Management of Fabry Disease 69,720 The Trustees of Columbia University The Columbia Renal Biopsy Course 5,000 in the City of New York Rheumatology Nurses Society Medscape Updates in RA, PsA, and Biosimilars: A Pipeline View 50,000 Education for the Clinical Nurse University of Illinois at Chicago Illinois Transplant Pharmacists Association Symposium 8,000 College of Pharmacy Rush University Medical Center Plexus Northern California Genitourinary Malignancy 10,000 Communications Symposium: Translating Clinical Advancements to Practical Patient Care Medscape, LLC Managing Multiple Myeloma: What's Next? 116,000 University of Louisville Research 11th Annual Perspectives in Rheumatic Diseases, 30,000 Foundation Inc. Global Academy for presented by Rheumatology News, Internal Medicine Medical Education Postgraduate News, Family Practice News Institute for Medicine AKH Inc, Advancing Knowledge in Focusing on the Patient Voice: Utilizing Components of 100,000 Healthcare 47-Consultants in Medical a Patient Coach Module Contextually within Patient- Education Centric CME Activities University of Colorado Denver Forty-fifth annual Renal Disease and Electrolyte 5,000 Disorders Course Annenberg Center for Health Sciences Advancing Knowledge to Practice: Optimizing Severe 200,000 at Eisenhower Asthma Care in the Age of Biologics USF Health i3 Health Challenges and Opportunities in Metastatic Castration- 90,000 Resistant Prostate Cancer: A CME/CE/CPE-Certified VA/ DoD Meeting Series Projects In Knowledge @Point of Care Multiple Sclerosis @Point of Care 75,000 New Jersey Academy of Family Ascertaining the Role of the Primary Care Clinician in 5,000 Physicians the Recognition and Management of Patients With Multiple Sclerosis in the Modern Era Med Learning Group Pathology-Based, Targeted Therapies--Managing Moderate- 124,745 to-Severe Atopic Dermatitis in Adults Annenberg Center for Health Sciences 2018 SUNA Advanced Prostate Cancer Grant 30,000 at Eisenhower Prostate Cancer Education Council Consortium of Multiple Sclerosis Immune Dysfunction in Multiple Sclerosis: Modern 75,000 Centers Catamount Medical Education Considerations in Treatment and Management Dallas County Optometric Society Eyes on Fabry Dallas County Optometric Society 9,266 Fabry Support & Information Group Association of Reproductive Health Snap, Crackle and Pop: Provider Education and Targeted 52,000 Professionals Training to Improve the Diagnosis and Therapeutic Management of Rheumatoid Arthritis in Female Patients AcademicCME Improving Individualized Outcomes in Asthma with 45,000 Evidence-based Treatment Strategies Integrity Continuing Education, Inc. 2018 Asthma State Society CME Meetings and BioDigital 319,350 Human On-demand Simulation Activity--Improving Severe Asthma Control through Comprehensive Patient Assessment and Tailored Treatment Selection UMA MLG, LLC Targeted Therapies for the Management of Moderate-to- 249,975 Severe Atopic Dermatitis in Adults--Animated Whiteboard View Society for Investigative Dermatology Neuro-Immunology of Skin Symposia 75,000 Penn State College of Medicine PVI, PeerView Live: ``Unraveling the Complex Treatment 60,000 PeerView Institute for Medical Landscape for Prostate Cancer: Guidance for Education, Inc. Delivering Evidence-Based, Patient-Centered Care'' Medscape, LLC Minimizing the Effects of TLS and CRS in Patients with 74,000 Hematologic Malignances Excel Continuing Education Unraveling the Genetics and Management of MPS 1 55,565 Hereditary Disease Foundation Hereditary Disease Foundation's ``Milton Wexler 10,000 Celebration of Life'' Symposium of international Huntington's disease researchers Medscape LLC Targeted Therapies for the Management of Severe 261,500 Asthma: Surveying an Evolving Landscape Seattle Children's Hospital PLUGS Summit 2018: Clinical Laboratory Stewardship: 8,000 Where Patient Safety and Financial Responsibility Meet University of Cincinnati Global Skin Disease Education Foundation's 14th Women's & 10,000 Academy for Medical Education Pediatric Dermatology Seminar Postgraduate Institute for Medicine Physicians' Education Resource, LLC 2018 ASH Symposium: ``D'' is for Diagnosis: Solving 250,000 (PER) the Mystery of Rare Hematologic Disorders Boston University School of Medicine, Practical Approach to Electromyography and 7,500 CME Neuromuscular Disorders Conference Specialty Pharma Education Center Renal Transplantation: Overview of Advances in 49,750 Clinical Understandings, Guidelines, and Treatment & Management Strategies University of California Irvine 8th Annual UC Irvine Neuromuscular Colloquium 20,000 Physicians' Education Resource, LLC Oncology BriefingsTM: Current Perspectives on 50,000 (PER) Preventing and Managing Tumor Lysis Syndrome UMA Education Inc., dba Global Nursing Management of Treatment-Related Side Effects 120,000 Education Group MCM Education in Metastatic Prostate Cancer UMA Education Inc., dba Global A Quality Improvement (QI) Educational Pilot on 107,155 Education Group Q Synthesis, LLC Enhancing Prostate Cancer Management in Urology Practice Med Learning Group Evolving Therapeutic Options for Moderate-to-Severe 274,785 Asthma: A Comprehensive 3-Dimensional Study University of Cincinnati 2018 International Rare Lung Diseases Research 10,000 Conference Consortium of Multiple Sclerosis Therapeutic Decision-Making for Disease Modification 49,288 Centers Inc. Delaware Media Group in MS: 2018 Update Excel Continuing Education Unraveling a Therapeutic Conundrum: ASMD Niemann Pick 106,790 Disease University of Cincinnati Advances in MauiDerm NP+PA Summer 2018 25,000 Cosmetic and Medical Dermatology American Thoracic Society ATS 2018 International Conference - Selected Sessions 20,000 in Asthma Creighton University Physicians Skin of Color Seminar Series 2018 (SOCSS 2018) 15,000 Continuing Education, Corporation UMA MLG, LLC Treating a Chronic Autoimmune Inflammatory Disease: 214,500 Targeting Pathophysiologic Cytokines in the Management of Rheumatoid Arthritis--Animated Whiteboard View Tarrant County Organization Society Eyes on Fabry Tarrant County Optometric Society 7,998 Fabry Support & Information Group University of Nevada, Reno School of 2018 Real World Dermatology for PAs and NPs 25,000 Medicine Dermatology University LLC American Society of Clinical 2018 ASCO Annual Meeting Genitourinary Cancer Tracks 40,000 Oncology, Inc. Conquer Cancer Bundle (Prostate and Nonprostate) Foundation of the American Society of Clinical Oncology Postgraduate Institute for Medicine Clinical Care Team Exchange: The Role of New Biologics 425,170 for Optimal RA Management PRIME Education, LLC Driving Practice Change in Systems-Based Care of 344,805 Patients with Atopic Dermatitis The Medical College of Wisconsin, The 23rd Annual Southwest Prostate Cancer Symposium 5,000 Inc. Carden Jennings Publishing Co., (SPCS 23) Ltd St. Joseph's Regional Medical Center Acute Rejection of the Allograft--New Concepts and Old 1,810 MS Cure Fund, Inc. 2018 Q1 Lifestyle Management Patient Education 20,000 Programs for individuals diagnosed with multiple sclerosis, and their support team. Alaska Regional Hospital Wheezin', Sneezin' & Itchin' in Alaska 5,000 American Academy of PAs AAPA 2018--Rheumatology Track 5,000 Postgraduate Institute for Medicine The Specialty Pharmacy Review BoardTM--Examining 235,000 Impact Education, LLC Emerging Biologics for Difficult-to-treat or Severe Asthma National Association of Managed Care Individualizing Therapy in the Management of Relapsing 45,000 Physicians Multiple Sclerosis: Expert Switching and Sequencing Strategies Consortium of Multiple Sclerosis Nursing Care in Multiple Sclerosis: Evidence-Based 75,000 Centers Inc. International Practice Organization of MS Nurses The Annenberg Center for Health How I Treat Advanced Prostate Cancer: Making Sense of 100,000 Sciences at Eisenhower prIME the Ever-Increasing Options Oncology, LLC Elsevier Office of Continuing Medical Clinical Issues in Atopic Dermatitis: Discussions and 784,642 Education Integritas Communications Debates on Managing Moderate-to-Severe Disease Horizon CME, Inc. How to Select and Start Insulin in Patients with Type 59,925 2 Diabetes: A Hands-on Workshop National Assocation For Continuing Getting Comfortable with Insulin: New Approaches to 355,396 Education Getting Patients Safely to Target Medscape LLC Improving Use of Basal Insulin for Better Diabetes 800,000 Outcomes Pri-Med Institute, LLC (d/b/a pmiCME) The Southern Diabetes Initiative: Individualizing Care 400,000 in the 21st Century Elsevier Office of Continuing Medical Emerging Strategies for Achieving Glycemic Control in 179,950 Education Adults with Type 1 Diabetes Collaboration \4\ The France Foundation When Insulin Isn't Enough: Exploring Dual SGLT1 and 153,900 SGLT2 Inhibition in T1DM Collaboration \4\ NACCME, LLC. Integrating Emerging Evidence in Adjunctive Therapies 432,535 Into Team-Based Management Strategies in Type 1 Collaboration \4\ Diabetes Med-IQ, LLC Evolving Evidence in Type 1 Diabetes Management: 238,281 Evaluating the Role of SGLT Inhibition Collaboration \4\ UMA Education Inc., dba Global Type 1 Diabetes: New and Emerging Therapeutic 511,628 Education Group Strategies to Address Unmet Needs Collaboration \4\ Haymarket Medical Education GLP-1 Receptor Agonists: Injecting More Confidence in 49,950 Achieving Glycemic Control for Patients With T2DM The my CME Town Wall: A Live Clinical Forum for Multiple Viewpoints on a Virtual Stage Medscape LLC Novel Treatments for T1D 499,000 Collaboration \4\ Med-IQ, Inc. Initiating Insulin in Patients Who Fear Needles: Using 297,385 Evolving Basal Insulins to Improve Adoption National Association of Managed Care The Role of PCSK9 Inhibitors in Lowering LDL-C in 95,000 Physicians Patients with Dyslipidemia: What Managed Care Needs Collaboration \3\ to Know Allina Health Minneapolis Heart PCSK9 Inhibitors--Science, Selection and Access 5,000 Institute Foundation Collaboration \3\ Medscape LLC PCSK9 Inhibitors and Cardiovascular Outcomes: ACC 2018 237,125 Data You Cannot Afford to Miss Collaboration \3\ Postgraduate Institute for Medicine The Landmark trial-based evidence and rationale for 398,000 CMEducation Resources, LLC PCSK9 inhibition to prevent and treat Atherosclerotic Collaboration \3\ Cardiovascular Disease (ASCVD) National Lipid Association Horizon PCSK9 Inhibitors in Practice: Real-World Challenges 261,335 CME, Inc. and Solutions Collaboration \3\ National Lipid Association The New Era of Preventive Cardiology: Applying PCSK9 153,000 Inhibitor Therapeutics to Prevent Heart Attack and Collaboration \3\ Stroke Postgraduate Institute for Medicine New Evidence-Based, Therapeutic Strategies for 397,000 CMEducation Resources, LLC applying CV outcome and trialbased evidence for PCSK9 Collaboration \3\ inhibition to the front lines of CAD Prevention and Treatment Med Learning Group A Virtual Reality Tour of Nonstatin LDL-C-lowering 573,725 Agents that Decrease Cardiovascular Risk for Patients Collaboration \3\ with Persistent Hypercholesterolemia Potomac Center for Medical Education Role of Interventional Cardiologists in Secondary 198,450 Prevention of Myocardial Infarction: Redefining Collaboration \3\ Clinical Practice North American Center for Continuing Cardiology Grand Rounds: Overcoming Access Barriers 476,838 Medical Education, LLC and Practice Challenges to PCSK9 Inhibitor Collaboration \3\ Implementation PRIME Education, LLC Applying the Latest Cardiovascular Outcomes Trial 146,740 Evidence to PCSK9 Inhibitor Decision-Making in Lipid Collaboration \3\ Management Pri-Med Institute, LLC (d/b/a pmiCME) Translating Evidence to Practice: Improving Outcomes 575,150 Horizon CME, Inc. in Patients with ASCVD with PCSK9 Inhibitors Collaboration \3\ Med Learning Group A Virtual Reality In Practice View: Maximizing 174,400 Clinical Benefit Through Optimal LDL-C Reductions in Collaboration \3\ Patients With Atherosclerotic Disease Physicians' Education Resource 2018 New York Multidisciplinary Cardio-Endo-Renal 35,000 Collaborative: Access to PCSK9i: Updates on Collaboration \3\ Guidelines, Emerging Cardiovascular Benefits and Overcoming Barriers to Access PRIME Education, LLC Integrating Evidence from the Latest Cardiovascular 459,799 Outcomes Data into Managed Care Decision-Making in Collaboration \3\ Lipid Management The Academy for Continued Healthcare Improving Outcomes and Expanding Opportunities for the 180,420 Learning Treatment of Hyperlipidemia Collaboration \3\ ---------------------------------------------------------------------------------------------------------------- \1\ Applicant names are provided by the requestor. If applicants apply as a group for a single educational activity; all applicants may be not be identified above. The Company funds other educational activities (including fellowships and non-physician and patient education); all of which do not appea r on this report, but appear on other reports on this site. \2\ ``Funding Amount'' is the amount that the Company funded during Q2, 2018 identified above based upon an agreement. Recipients are required to return any unused funds. Information on unused funds returned by the applicant on activities are not reported. ``Funding Amount'' does not include funds that may have been provided by other affiliated Sanofi Company Entities (e.g., Sanofi Pasteur). \3\ Collaboration (Shared) Funding--is the full amount of a grant funded under an agreement with Regeneron, some or all of which may be shared between the collaborating entities. \4\ Collaboration (Shared) Funding--is the full amount of a grant funded under an agreement with Lexicon, some or all of which may be shared between the collaborating entities. Independent Medical Education Grants 1st July 2018-30th Sept 2018 Sanofi US and its affiliate Genzyme Corporation are committed to supporting independent medical education activities in therapeutic areas in which the Company is involved, for healthcare professionals, patients, and consumers to improve patient care and health outcomes in therapeutic areas in which the Company is engaged. Sanofi US and Genzyme Corporation are part of the Sanofi Group, a global pharmaceutical company. ---------------------------------------------------------------------------------------------------------------- Funding Amount Recipient Name(s) \1\ Activity Title ($) \2\ ---------------------------------------------------------------------------------------------------------------- Integrity Continuing Education, Inc. Advancing Diagnosis and Management of Atopic 318,450 Dermatitis in Children and Adolescents-- Practitioner's Edge State Society Meeting Series, CaseScribe On-demand Activity, and Mobile Coach Platform Penn State College of Medicine PVI, PeerView inSession, ``An Expert Analysis of New Data 76,740 PeerView Institute for Medical for Uncontrolled Persistent Asthma Treatments: Education, Inc. Clinical Updates From Paris'' Medscape LLC Advances in Severe Asthma Management: Conference 219,500 Highlights and Perspectives PRIME Education, LLC 4th Annual Regional Meetings for Providers in Federal 188,000 and Public Healthcare Sectors: Interprofessional Education on Psoriatic Diseases, Atopic Dermatitis, and Rheumatoid Arthritis Medscape LLC Guide to Atopic Dermatitis: Clinical Pearls for 198,400 Dermatologists and Allergists MediCom Worldwide, Inc. 2018 ASH Meeting on Hematologic Malignancies: The Art 25,000 and Science of Relapsed/Refractory Multiple Myeloma: A Practical Guide to Complex Therapeutic Choices Medscape LLC The Pediatrician's Role in Atopic Dermatitis 458,225 Integrity Continuing Education, Inc. Strategies to Provide Individualized Treatment in 360,900 Moderate-to-Severe Atopic Dermatitis--Practitioner's Edge State Society Meeting Series and Publication in Action On-demand Activity Regents of the University of Frontiers in Autosomal Dominant Polycystic Kidney 10,000 California Disease (ADPKD) National Association of Managed Care Optimizing Clinical and Economic Outcomes in the 57,000 Physicians Management of Moderate to Severe Atopic Dermatitis: Taking a Closer Look at the Role of Biologic Therapies National Jewish Health Catamount What is Multiple Myeloma? A Game-Based Learning 75,000 Medical Education, LLC Experience on Novel Treatment Strategies for MultipleMyeloma Medical Learning Institute, Inc. PVI, PeerView inVision, Expert Insights on Available and 122,250 PeerView Institute for Medical Emerging Therapies for the Management Pompe Disease Education, Inc. ScientiaCME LLC Treatment strategies in Fabry disease 17,800 UMA MLG, LLC Utilizing the Molecular/Physiologic Phenotype to 289,400 Direct Asthma Therapy: A Comprehensive Infographic View CME Outfitters, LLC Atopic Dermatitis: You Can't Improve What You Don't 279,850 Measure The University of Kansas Medical The Changing Landscape of Neuromuscular Disease: The 40,000 Center--Continuing Medical Education Future is Here Oakstone Publishing, LLC. Getting Under the Skin with Targeted Therapy to 170,000 Improve Atopic Dermatitis Management University of Cincinnati Global 14th Annual Coastal Dermatology Symposium 10,000 Academy for Medical Education Postgraduate Institute For Medicine MediCom Worldwide, Inc. 2018 Meeting Highlights of the 4th International 12,500 Conference on Multiple Myeloma National Comprehensive Cancer Network NCCN 13th Annual Congress: Hematologic MalignanciesTM 25,000 Boston Children's Hospital/Division Metabolism Conference Series 10,000 of Genetics and Genomics Postgraduate Institute for Medicine Incorporating New Agents into the Management of Atopic 375,400 PlatformQ Health Education, LLC Dermatitis Asthma and Allergy Foundation of America Purdue University MCM Education Improving the Management of Severe Asthma in Patients 125,000 with Type 2 Inflammation Cedars-Sinai 8th Annual Symposium on Lysosomal Storage Disorders 20,000 AMERICAN UROLOGICAL ASSOCIATION Use of Novel Hormonal Agents and Systemic Therapy in 50,000 Advanced Prostate Cancer Med Learning Group In Pursuit of Clinical Remission: Optimizing the 249,850 Pharmacologic Management of Rheumatoid Arthritis Physicians' Education Resource, LLC Cancer Summaries and CommentariesT: Report from San 50,000 (PER) Diego on Advancements in Multiple Myeloma Physicians' Education Resource, LLC 2019 ASCO GU Symposium: Prostate Cancer Tumor Board: 100,000 (PER) Integration of Recent Data Sets Across Lines of Care University of Pittsburgh 2018 Pittsburgh International Lung Conference-- 10,000 Pulmonary Medicine: Basic Biology and Novel Therapies American College of Chest Phys Update on Moderate-to-Severe Asthma for Specialists: 500,000 Conference Coverage from CHEST 2018 American Academy of Physician 10th Annual Allergy, Asthma & ENT CME Conference 5,000 Assistants in Allergy, Asthma & Immunology Oakstone Publishing, LLC Answers in Strategies for Success in Rheumatoid Arthritis 170,000 CME Inc. Treatment: Integrating the Patient Voice American College of Allergy, Asthma & An interactive Case Discussion of a Young Adult with 40,000 Immunology Severe Atopic Dermatitis: Insights from the Expert UT Southwestern Medical Center Treatment Approaches and Therapies for Highly Active 83,350 Medical Logix, LLC Multiple Sclerosis: Implementing Updated MS Guidelines National Association of Managed Care Implementing Personalized Therapeutic Strategies of 45,000 Physicians Switching and Sequencing to Improve Patient Outcomes in the Management of Multiple Sclerosis Projects In Knowledge MedImage Cases: Multiple Sclerosis 75,000 American Society of Transplant 12 Annual Surgical Fellows Symposium 110,000 Surgeons Medscape LLC Management Challenges in Rheumatoid Arthritis: A 250,000 Virtual Simulation Approach Michael J. Fox Foundation For MDS-PAS Movement Disorders School for Neurology 20,000 Parkinson's Research Residents Society for Inherited Metabolic 2018 North American Metabolic Academy 25,000 Disorders Duke University 2018 Duke Solid Organ Transplant Summit 15,000 American Society of Nephrology Fabry Disease for the Nephrologist: Present and Future 125,000 University of Minnesota American College of Allergy, Asthma & Thursday Morning Session: Biologic Therapies in Your 77,875 Immunology Practice Physicians' Education Resourcer Advances inTM Therapies for Patients with Multiple 60,000 (PER) Myeloma: More Options. More Decisions. Better Outcomes Oakstone Publishing, LLC Answers in Making the Case for Stepping Up Therapy for Atopic 185,000 CME Inc. Dermatitis Oakstone Publishing, LLC Answers in Assessing the Impact of AD: Physical and Beyond 170,000 CME Inc. Postgraduate Institute for Medicine Recognizing and Managing Suboptimal Therapeutic 35,000 Enquiring Minds, LLC Response in MS: Expert Guidance on Challenging Cases JPatible JPatible Jewish Genetic Screening and Couple 77,500 Compatibility Matching Program Illinois Academy of Physician Multiple Sclerosis 6,500 Assistants American Society for Reconstructive Vascularized Composite Tissue Allografts: What it 30,152 Transplantation Takes to Succeed Massachusetts Association of ``Multiple Sclerosis'' 4,800 Physician Assistants i3 Health Castration-Resistant Prostate Cancer: Implementing New 86,975 Data and Evolving Standards Mayo Clinic College of Medicine and International Myeloma Society Educational Workshop 50,000 Science SPARGO Inc. on behalf of the International Myeloma Society UCSF Office of CME UCSF TRANSPLANT 2018: Pioneering Advances in 5,000 Transplantation The University of Texas MD Anderson Emerging Therapeutic Strategies for Relapsed and 50,000 Cancer Center ASiM CE, LLC Refractory Multiple Myeloma: Highlights from ASH 2018 Regents of the University of Colorado 88th Annual Meeting of the American Thyroid 75,000 American Thyroid Association Association and the 2018 Annual Ridgway Trainee Conference National Assocation For Continuing Matching Pathogenesis and Treatment in Atopic 92,800 Education Dermatitis: The Evolving Science The Medical College of Wisconsin PVI, PeerView Live at the 2019 TCT Meetings--``Innovative 119,477 PeerView Institute for Medical Therapies and Concepts in Transplant-Eligible Education Patients With Myeloma: Advancing Toward More Effective Care Across Treatment Settings'' Physicians' Education Resource, LLC Medical Crossfire: How Can We Best Leverage the Use 50,000 (PER) of MRD to Optimize Outcomes in the Management of Hematologic Malignances? Postgraduate Healthcare Education, Identification and Management of Atopic Dermatitis: 154,500 LLC Postgraduate Institute for Applying Advances to Improve Outcomes A PHE/Power-Pak Medicine (PIM) Initiative Program 2: Treatment and Emerging Therapies in Moderate-to-Severe Atopic Dermatitis Physicians' Education Resource, LLC Optimizing Outcomes Through Stem Cell Mobilization: 300,000 (PER) The Medical College of Applying Evidence to Patients with Multiple Myeloma Wisconsin, Inc. and Non-Hodgkin's Lymphoma Continuing Education Alliance PCE Directed Learning eCourse plus eMinders and 148,275 Reinforcements: Changing Pathways in Moderate to Severe Atopic Dermatitis American Academy of CME, Inc. Reversing the Trend in Living Kidney Donation: 122,875 Improving Risk Assessment and Increasing Access Postgraduate Institute for Medicine Applying Precision Medicine in Severe and Difficult-to- 322,100 Treat Asthma. Penn State College of Medicine Consensus or Controversy? Clinical Investigators 95,000 Research To Practice Provide Perspectives on the Current and Future Management of Patients with Prostate Cancer--An Independent Satellite Symposium (ISS) Held as a Premium Ancillary Educational Event During the 2019 Genitourinary Cancers Symposium Excel Continuing Education Newborn Screening for Rare Disorders: Focusing on 77,575 Pompe Disease and Gaucher Disease Excel Continuing Education ``Multiple Sclerosis: Treating and Managing Symptoms'' 5,000 Medical Learning Institute, Inc. PVI, PeerView inSession, Taking Stock of Late-Breaking Data 50,000 PeerView Institute for Medical on Disease-Modifying Therapies for the Treatment of Education, Inc. Multiple Sclerosis: What Are the Key Learnings from Berlin? UMA MLG, LLC A 3D View: Moderate-to-Severe Atopic Dermatitis in the 425,000 Pediatric Population: Long-term Treatment and Managed Care Issues Postgraduate Institute for Medicine A Learning Pathway for Clinicians in Multiple 50,000 RMEI Sclerosis: Practical Strategies for Early Diagnosis and Informed Management Postgraduate Institute for Medical Atopic Dermatitis: A Specialist Perspective on 300,000 Education Global Academy for Medical Diagnosis and Management Across the Age Spectrum Education American Academy of CME, Inc Crucial Conversations in Rare & Orphan Disease: 36,000 Challenges of Diagnosing Rare Diseases: A Focus on Gaucher Disease Consortium of Multiple Sclerosis Improving Multiple Sclerosis Care: Integrating Patient- 60,000 Centers PlatformQ Health Education, Provider Perspectives LLC Postgraduate Healthcare Education The Pharmacist's Role in Managing Disease-Modifying 30,000 Spire Learning Therapies in Adults With Multiple Sclerosis Integrity Continuing Education, Inc. Improving Diagnosis and Treatment of Atopic Dermatitis 299,800 through Collaborative Primary & Specialist Care-- Practitioner's Edge State Society Meeting Series and CME Audit and Feedback Practice Assessment Regents of the University of Colorado Practical Ways to Achieve Targets in Diabetes Care 25,000 (ATDC) Collaboration \4\ Regents of the University of Colorado Practical Ways to Achieve Targets in Diabetes Care 50,000 (ATDC) Regents of the University of Colorado Practical Ways to Achieve Targets in Diabetes Care 75,000 (ATDC) Horizon CME, Inc. Can We Do It Better: Improving Outcomes in the 165,100 Management of Patients with Atrial Fibrillation Integrity Continuing Education, Inc. 2019 AAFP State Society CME Meetings, Hands-on 160,000 Workshop And BioDigital Human On-demand Simulation Activity: Overcoming Barriers to Initiating or Intensifying Insulin Therapy: Best Practices for the Family Physician NACCME, LLC. Cardiology Grand Rounds: Diagnostic and 221,710 Pharmacotherapeutic Strategies for the Individualized Management of Atrial Fibrillation University of Cincinnati New Developments in Type 2 Diabetes Treatment to 275,000 Decrease the Risk of Hypoglycemia Medscape LLC Lipid Clinic Considerations: What Would You Do? A Live 447,220 Patient Simulation Collaboration \3\ PRIME Education, LLC Patients, Payers, Providers Opine: When to Treat with 445,879 PCSK9s Collaboration \3\ Boston University School of Medicine 2018 PCE Series 3 Live and Enduring Home Study with 225,000 Practicing Clinicians Exchange (PCE) Eminders and Reinforcement Activities--Evolution of Collaboration \3\ Dyslipidemia Management: The Expanding Role of PCSK9 Inhibitors Association of Black Cardiologists, Managing Lipids and Cardiovascular Risk: Using the 250,000 Inc. Data to Optimize Care Collaboration \3\ Pharmacy Times Continuing Education An American Journal of Managed Care (AJMC) Payor and 51,850 Specialty Pharmacy Forum: Discussing Clinical Updates Collaboration \3\ and Outcomes Data for PCSK9 Inhibitors Med-IQ, Inc. Exploring Treatment Intensification in Type 2 250,050 Diabetes: Focus on the Provider-Patient Collaborative UMA MLG, LLC An In Practice View: Moving Beyond Statins To Decrease 178,150 Cardiovascular Events in Patients With Collaboration \3\ Atherosclerotic Disease Oakstone Publishing, LLC Answers in Putting Cardiovascular Outcomes Data Into Context: How 170,000 CME Inc. Will the Latest Information on PCSK9 Inhibitors Collaboration \3\ Change Practice? ---------------------------------------------------------------------------------------------------------------- \1\ Applicant names are provided by the requestor. If applicants apply as a group for a single educational activity; all applicants may be not be identified above. The Company funds other educational activities (including fellowships and non-physician and patient education); all of which do not appear on this report, but appear on other reports on this site. \2\ ``Funding Amount'' is the amount that the Company funded during Q3, 2018 identified above based upon an agreement. Recipients are required to return any unused funds. Information on unused funds returned by the applicant on activities are not reported. ``Funding Amount'' does not include funds that may have been provided by other affiliated Sanofi Company Entities (e.g., Sanofi Pasteur). \3\ Collaboration (Shared) Funding--is the full amount of a grant funded under an agreement with Regeneron, some or all of which may be shared between the collaborating entities. \4\ Collaboration (Shared) Funding--is the full amount of a grant funded under an agreement with Lexicon, some or all of which may be shared between the collaborating entities. Independent Medical Education Grants 1st Oct 2018--31st Dec 2018 Sanofi US and its affiliate Genzyme Corporation are committed to supporting independent medical education activities in therapeutic areas in which the Company is involved, for healthcare professionals, patients, and consumers to improve patient care and health outcomes in therapeutic areas in which the Company is engaged. Sanofi US and Genzyme Corporation are part of the Sanofi Group, a global pharmaceutical company. ---------------------------------------------------------------------------------------------------------------- Funding Amount Recipient Name(s) \1\ Activity Title ($) \2\ ---------------------------------------------------------------------------------------------------------------- NACCME, LLC Horizon CME Clinical and Cost Considerations for Value-Based 74,875 Multiple Sclerosis Care AKH, Inc. Catalyst Medical Education, Improving Care for Patients with Pompe Disease: A Look 239,740 LLC at Emerging Therapies and Multidisciplinary Management Strategies Medical Education Resources Impact Managing Clinical and Cost Outcomes in Multiple 75,000 Education, LLC Sclerosis: Expert Insights i3 Health Current Trends in the Management of Castration- 47,530 Resistant Prostate Cancer Oakstone Publishing, LLC Answers in A Breath of Fresh Air: Exploring Pathophysiology and 340,000 CME Inc. Novel Therapeutic Options to Improve Outcomes in Moderate-to-Severe Asthma ANA NY, ISONG 2018 ISONG Congress--Building Connections to Genomic 2,500 Health Affinity CE/PESG LDRTC Genetic Rare and Immune Disorders Symposium-GRIDS 2018 50,000 GRIDS 2018 title: Late and Attenuated Presentations of Lysosomal Storage Disorders UMA MLG, LLC A Virtual Reality Experience--Pediatric Atopic 230,950 Dermatitis: Treatment and Management UMA MLG, LLC A Virtual Reality View--Long-term Management of Atopic 449,550 Dermatitis: New and Emerging Targeted Systemic Therapies UMA Education, Inc. dba Global Clinical Issues in Atopic Dermatitis: Discussions and 168,203 Education Group Integritas Debates on Improving Outcomes for Moderate-to Severe Communications Disease National Kidney Foundation Evidence-Based New Insights on the Management of Fabry 145,000 Disease UMA Education Inc., dba Global Looking Ahead: Optimizing Management Strategies in 393,362 Education Group Integritas Moderate-to-Severe Atopic Dermatitis Communications Postgraduate Healthcare Education, Type 1 Gaucher Disease: Optimizing Treatment and 63,950 LLC Postgraduate Institute for Management Approaches Medicine (PIM) The France Foundation Severe Asthma Science: Endotypes and Precision 292,680 Medicine Presidential Case Studies UMA Education, Inc dba Global Clearing the Air in Severe Asthma Management: 549,981 Education Group Integritas Improving Patient Outcomes Through Shared Clinical Communications Decision Making AKH Inc. Advancing Knowledge in Masters of Pediatric Dermatology 20,000 Healthcare Tarsus Cardio dba South Beach Symposium PRIME Education, LLC Atopic Dermatitis Across the Life Cycle: Taking the 199,700 Long View on Diagnostic, Treatment, and Management Strategies PRIME Education, LLC Linking Patients, Providers, and Payers in Coordinated 316,500 Approaches to Severe Asthma Treatment AKH Inc., Advancing Knowledge in 17th Annual South Beach Symposium 20,000 Healthcare Tarsus Cardio PRIME Education, LLC Stepping Up Managed Care and Specialty Pharmacy 499,075 Decision-Making to Support Integration of New Evidence and Mechanisms in Asthma Treatment Academy of Managed Care Pharmacy AMCP Specialty Connect--Focus on Gene Therapy 35,000 (AMCP) UMA MLG, LLC The Unique Role of the Community Pharmacist in the 199,550 Management of Moderate-to-Severe Atopic Dermatitis in the Pediatric Population Rush University Medical Center Plexus Applying the Latest Clinical Data and Emerging 60,000 Communications Therapeutic Approaches in the Management of Prostate Cancer Throughout the Disease Spectrum Purdue University College of Pharmacy PeerView Live, ``Unraveling the Complexities of 109,387 PVI, PeerView Institute for Medical Prostate Cancer Management: Focus on Therapeutic Education, Inc. Decisions for Early Stage Disease and the Implications for Later Stage Disease'' Rush University Medical Center Plexus Community Uro-Oncology Forums: Understanding the 80,000 Communications Disease Continuum and Navigating the Evolving Treatment Paradigms in Prostate Cancer American Health Resources, LLC Updates in Myeloma Therapeutics: Bone Health, 8,000 Smoldering Disease, and CAR-T Cells Siyemi Learning Action Eczema: Global Atopic Dermatitis Educational 383,320 Resource Center ScientiaCME Genetic Disorders: Updates from The 15th Annual World 17,800 Symposium NERGG, Inc. NERGG 2018 Annual Meeting 6,000 UMA MLG, LLC The CATALYST Initiative--A 3D View--Targeting 348,275 Inflammatory Cytokines: Addressing Articular and Systemic Pathology in Patients with Moderate-to- Severe Rheumatoid Arthritis University of Nevada, Reno School of 2018 Fall Clinical Dermatology Conferencer and Beyond: 150,000 Medicine Foundation for Research and Practical Approaches to Patient Management--Focus on Education in Dermatology Atopic Dermatitis Trustees of Boston University Talem Talem ACO Summit Series--Atopic Dermatitis: Improving 198,555 Health, LLC Outcomes Through a Patient-Centered Approach Cleveland Clinic Educational 7th Annual Basic & Clinical Immunology for the Busy 15,000 Foundation Clinician University of Nebraska Medical Center Rural Health Summit Series: Updates in Atopic 201,343 The Board of Regents of the Dermatitis for the Rural Primary Care Physician University of Nebraska dba the University of Nebraska Medical Center International Eczema Council Atopic Dermatitis Phenotypes and Biomarkers 11,500 Excel Continuing Education Fabry Disease: Role of the Genetic Counselor in an 81,900 Ever-Changing Landscape; The Role of the Genetic Counselor in Pompe Disease Specialty Pharma Education Center Advancing Care in Prostate Cancer: Clinical 49,750 Understandings & Evolving Treatment and Management Approaches Massachusetts Eye And Ear Infirmary, Surgery of the Thyroid and Parathyroid Glands 15,000 Department of Otolaryngology President and Fellows of Harvard College Rush University Medical Center Plexus VHA UroOncology Clinical Forums ``Advancing Strategies 90,000 Communications in Prostate Cancer: Individualizing Treatment Plans Based on the Rapidly Evolving Landscape and Disease Continuum'' Physicians' Education Resource, LLC ``D'' is for Diagnosis: Solving the Mystery of 100,000 (PER) Lysosomal Storage Disorders Muscular Dystrophy Association Medical Education Tactics for the Physician and Care 211,525 Center Community: Hot Topics in NMD Webcast and MDA Speaker Slides Med-IQ, Inc. Bridging the Gap Between Research and Clinical 245,887 Advances in Gaucher Disease Type 3 Medical Education Resources, Inc. Managing Multiple Sclerosis: A Guide for Specialty 75,000 Impact Education, LLC Pharmacy Professionals Med Learning Group A Multiple Sclerosis Virtual Reality Experience: 50,000 Reaching Diagnosis, Delivering Treatment, and Setting Goals for Long-Term Success Integrity Continuing Education, Inc. 2019 AAFP State Society CME Meetings and BioDigital 299,000 Human On-demand Simulation Activity--Ensuring Early Diagnosis and Targeting Treatment to Remission in Patients with Rheumatoid Arthritis: Recommendations for Primary Care Clinicians Yale School of Medicine 2019 Update: What's New in the Field of Multiple 15,000 Sclerosis Annenberg Center for Health Sciences 11th Annual Linda Morgante MS Nurse Leadership Program 45,000 at Eisenhower Academy for Continued Healthcare Learning Physicians' Education Resource, LLC 2019 ACTRIMS: An Interactive, Case-Based Discussion: 212,000 (PER) Interpreting the Therapeutic Landscape in Multiple Sclerosis The Medical College of Wisconsin, 29th Annual International Prostate Cancer Update (IPCU 15,000 Inc. Carden Jennings Publishing Co., 29) Ltd. UMA MLG, LLC In Pursuit of the Best Outcomes in Rheumatoid 194,680 Arthritis: Inhibiting Inflammatory Pathology NJ State Society of Physician Focus on the Future 21,000 Assistants College of Saint Elizabeth Postgraduate Institute for Medicine Lysomal Storage Disorders--Common Presetations of 99,885 Enquiring Minds, LLC Uncommon Diseases: Expert Guidance on Early Identification and Therapeutic Optimization Greenwood Genetic Center Spring 2019 and Spring 2020 educational program: 82,003 Enhancing genetic understanding of lysosomal storage diseases for practicing Physician Assistants (PA) and PA students ThinkGenetic Foundation Closing the Genetics Gap: A Lecture for Healthcare 9,320 Advocates on Lysosomal Storage Diseases Designed to Increase Access to Genetics Services in Medically Underserved Parishes of Louisiana National Association for Continuing Conversations in Primary Care 2019 Live Virtual 64,000 Education Symposium Series Individualizing Asthma Care: Addressing Type 2 Inflammation Excel Continuing Education Newborn Screening for Fabry Disease: What 86,735 Neonatologists and Pediatricians Needs to Know Excel Continuing Education Exploring the Genetic Counselor's Role in Gaucher 42,330 Disease (satellite symposium at NSGC) Mayo Clinic Arizona Mayo Clinic 2019 Multiple Sclerosis & Autoimmune 7,500 Neurology Update UT Southwestern Medical Center 41st Annual Carrell Krusen Neuromuscular Symposium 5,000 Medscape LLC Improving Appropriate Use of PCSK9 Inhibitors in 736,125 Interventional Cardiology: Patient-Centered Care Collaboration \3\ Perspectives Post-MI Postgraduate Institute for Medicine The iQ&A Case-by-Case, PCSK9 Cardiovascular Medicine 488,000 Intelligence zone: from trials to treatment-How Do Collaboration \3\ Recent Guidelines and CV Outcome Trials Help Identify High Risk Patients (Elevated LDL-C, Recent ACS, Advanced ASCVD, PCI, Statin Intolerance and Resistance, and Diabetes) Who Are Optimal Candidates for PCSK9 Inhibitor-Mediated Therapy ---------------------------------------------------------------------------------------------------------------- \1\ Applicant names are provided by the requestor. If applicants apply as a group for a single educational activity; all applicants may be not be identified above. The Company funds other educational activities (including fellowships and non-physician and patient education); all of which do not appear on this report, but appear on other reports on this site. \2\ ``Funding Amount'' is the amount that the Company funded during Q4, 2018 identified above based upon an agreement. Recipients are required to return any unused funds. Information on unused funds returned by the applicant on activities are not reported. ``Funding Amount'' does not include funds that may have been provided by other affiliated Sanofi Company Entities (e.g., Sanofi Pasteur). \3\ Collaboration (Shared) Funding--is the full amount of a grant funded under an agreement with Regeneron, some or all of which may be shared between the collaborating entities. \4\ Collaboration (Shared) Funding--is the full amount of a grant funded under an agreement with Lexicon, some or all of which may be shared between the collaborating entities. Organization Name ------------------------------------------------------------------------ ------------------------------------------------------------------------ Hawaii Chapter--National Hemophilia The Coalition for Hemophilia B Foundation Hemophilia of North Carolina Virginia Hemophilia Foundation Hemophilia Foundation of Greater West Virginia Chapter National Florida Hemophilia Foundation The Coalition for Hemophilia B Brandywine Valley Hemophilia Annual Reqests Foundation Arizona Hemophilia Association Hemophilia Association of the Capital Area Central California Hemophilia National Hemophilia Foundation, Foundation Colorado Chapter Hemophilia Foundation of Arkansas, Hemophilia Foundation of Northern Inc. California United Hemophilia Foundation, Inc. Lone Star Chapter of the National Hemophilia Foundation Lone Star Chapter of the National Mississippi Hemophilia Foundation Hemophilia Foundation Lone Star Chapter of the National Lone Star Chapter of the National Hemophilia Foundation Hemophilia Foundation Utah Hemophilia Foundation Hemophilia Association of the Capital Area Florida Hemophilia Association Great Lakes Hemophilia Foundation Bleeding Disorders Alliance Gateway Hemophilia Association Illinois Arizona Hemophilia Association Tennessee Hemophilia and Bleeding Disorders Foundation Hemophilia Foundation of Northern Nebraska Chapter of the National California Hemophilia Foundation Hemophilia Association of the Northern Ohio Hemophilia Foundation Capital Area Hemophilia Foundation of Southern Hemophilia Foundation of Southern California California Hemophilia Alliance of Maine Bleeding Disorders Association of Northeastern New York, Inc. Connecticut Hemophilia Society, Idaho Chapter of the National Inc. Hemophilia Foundation Hemophilia Foundation of Minnesota/ Hemophilia Foundation of Michigan Dakotas Oklahoma Hemophilia Foundation Hemophilia and Bleeding Disorders of Alabama, Inc. Cooley's Anemia Foundation Oklahoma Hemophilia Foundation Louisiana Hemophilia Foundation Gateway Hemophilia Association Virginia Hemophilia Foundation Virginia Hemophilia Foundation Utah Hemophilia Foundation Alaska Hemophilia Association Nevada Chapter of the National Utah Hemophilia Foundation Hemophilia Foundation Alaska Hemophilia Association Hemophilia of South Carolina Hemophilia Foundation of Oregon Tennessee Hemophilia and Bleeding Disorders Foundation Tennessee Hemophilia and Bleeding Hemophilia Foundation of Greater Disorders Foundation Florida Hemophilia of Indiana, Inc. Hemophilia Foundation of Maryland, Inc. Hemophilia Foundation of Maryland Northern Ohio Hemophilia Foundation Inc. National Hemophilia Foundation, National Hemophilia Foundation, Colorado Chapter Colorado Chapter New England Hemophilia Association Hemophilia Foundation of Arkansas, Inc. New England Hemophilia Association New York City Hemophilia Chapter Hemophilia Foundation of WNY, INC. The Coalition for Hemophilia B Woman's Retreat Arizona Hemophilia Association Hemophilia Foundation of Greater Florida The Bleeding Disorder Foundation of National Hemophilia Foundation Washington The Hemophilia Association of New Great Lakes Hemophilia Foundation Jersey The Hemophilia Association of New Texas Central Hemophilia Jersey Association National Hemophilia Foundation, Hemophilia Association of San Diego Colorado Chapter County Kentucky Hemophilia Foundation Kentucky Hemophilia Foundation (KHF) (KHF) Kentucky Hemophilia Foundation Central California Hemophilia (KHF) Foundation West Virginia Chapter of the Foundation for Sickle Cell Disease National Hemophilia Foundation Research Federation of American Societies Gateway Hemophilia Association for Experimental Biology Great Lakes Hemophilia Foundation Hemophilia Foundation of Southern California United Hemophilia Foundation, Inc. Florida Hemophilia Association Hemophilia Foundation of Southern Nevada Chapter of the National California Hemophilia Foundation Nevada Chapter of the National Hemophilia of North Carolina Hemophilia Foundation Hemophilia of North Carolina Hemophilia of Indiana, Inc. Hemophilia of Indiana, Inc. Hemophilia of Indiana, Inc. Hemophilia Association of San Diego Hawaii Chapter--National Hemophilia County Foundation Oklahoma Hemophilia Foundation Disabled Adventure Outfitters National Hemophilia Foundation, Hawaii Chapter--NHF Colorado Chapter Rocky Mountain Hemophilia & Rocky Mountain Hemophilia & Bleeding Disorders Association Bleeding Disorders Association Virginia Hemophilia Foundation Hemophilia Association of the Capital Area Hemophilia Association of the The Western Pennsylvania Chapter of Capital Area the National Hemophilia Foundation Lone Star Chapter of the National Central Ohio Chapter, NHF Hemophilia Foundation Bleeding Disorders Alliance Central California Hemophilia Illinois Foundation Hemophilia Alliance of Maine New England Hemophilia Asssociation Alaska Hemophilia Association FAMOHIO, Inc. FOUNDATION HOPE AND LIFE USA CORP. National Hemophilia Foundation Midwest Hemophilia Association Great Lakes Hemophilia Foundation Hemophilia Foundation of WNY, INC. Utah Hemophilia Foundation Hope for Hemophilia Hope for Hemophilia West Virginia Chapter of the Hemophilia of Iowa, Inc. National Hemophilia Foundation New York City Hemophilia Chapter New England Hemophilia Association Association of Pediatric Hematology SISTERS AND CAREGIVERS BLEEDING Oncology Nurses DISORDER NETWORK, INC DBA BLOOD B National Hemophilia Foundation, Colorado Chapter, National Colorado Chapter Hemophilia Foundation American Society of Hematology Hemophilia Association of the Southern Tier, Inc. Mississippi Hemophilia Foundation New York City Hemophilia Chapter Comprehensive Health Education New England Hemophilia Association Services Northern Ohio Hemophilia Foundation Hemophilia Association of the Capital Area Global Genes Mary M. Gooley Hemophilia Center, Inc. Midwest Hemophilia Association Hemophilia of South Carolina Arizona Hemophilia Association Sickle Cell Disease Association of America, Inc. Hemostasis and Thrombosis Research Greater Boston Sickle Cell Disease Society, Inc. Association, Inc. Bleeding Disorders Alliance Hope for Hemophilia Illinois Central Ohio Chapter National New York City Hemophilia Chapter Hemophilia Foundation New York City Hemophilia Chapter The Hemophilia Association of New Jersey Arizona Hemophilia Association Nebraska Chapter of the National Hemophilia Foundation Nevada Chapter of the National Sickle Cell Disease Association of Hemophilia Foundation America, Michigan Chapter Hemophilia of South Carolina Hemophilia of Iowa, Inc. Empowering Women with Bleeding and Tennessee Hemophilia and Bleeding Clotting Disorders (Global Blood Disorders Foundation Disorder Foundation) Hemophilia Foundation of Oregon The Hemophilia Association of New Jersey Hemophilia Foundation of Arkansas, Connecticut Hemophilia Society, Inc. Inc. Bleeding Disorders Advocacy Network National Hemophilia Foundation, West Virginia Chapter New England Hemophilia Association Western Pennsylvania Chapter of the National Hemophilia Foundation Virginia Hemophilia Foundation Hemophilia Foundation of Greater Florida Hemophilia Foundation of Greater National Hemophilia Foundation, Florida West Virginia Chapter Idaho Chapter of the National Tri-State Bleeding Disorder Hemophilia Foundation Foundation Northwest Ohio Hemophilia New York City Hemophilia Chapter Foundation Hemophilia Association of the Hemophilia Foundation of Southern Capital Area California Hemophilia of North Carolina Oklahoma Hemophilia Foundation Bleeding Disorders Association of Louisiana Hemophilia Foundation Northeastern New York, Inc. Eastern Pennsylvania Chapter of the Sangre De Oro, Inc. National Hemophilia Foundation National Hemophilia Foundation Midwest Hemophilia Association United Hemophilia Foundation, Inc. Texas Central Hemophilia Association Hemophilia Foundation of Northern Central Ohio Chapter, NHF California The Bleeding Disorder Foundation of Nebraska Chapter of the National Washington Hemophilia Foundation The Coalition for Hemophilia B Northern Ohio Hemophilia Foundation West Virginia Chapter of the Hemophilia and Bleeding Disorders National Hemophilia Foundation of Alabama, Inc. Academia Medica del Sur, Inc. Hemophilia Association of New York, Inc. Texas Central Hemophilia New York City Hemophilia Chapter Association Tri-State Bleeding Disorder Hemophilia Alliance of Maine Foundation Nevada Chapter of the National FOUNDATION HOPE AND LIFE USA CORP. Hemophilia Foundation Central California Hemophilia American Society of Gene & Cell Foundation Therapy The Coalition for Hemophilia B Virginia Hemophilia Foundation Nevada Chapter of the National Hemophilia Association of the Hemophilia Foundation Capital Area Hemophilia Council of California Hemophilia Foundation of Maryland, Inc. Tri-State Bleeding Disorder Hemophilia Foundation of Southern Foundation California United Hemophilia Foundation, Inc. The Bleeding Disorder Foundation of Washington The Bleeding Disorder Foundation of Rocky Mountain Hemophilia & Washington Bleeding Disorders Association New England Hemophilia Association Arizona Hemophilia Association Hemophilia Foundation of Maryland Western Pennsylvania Chapter of the National Hemophilia Foundation Western Pennsylvania Chapter of the Hemophilia Foundation of Arkansas, National Hemophilia Foundation Inc. Virginia Hemophilia Foundation Virginia Hemophilia Foundation Hemophilia Foundation of Southern Hemophilia Council of California California Hemophilia Foundation of Maryland, The Western Pennsylvania Chapter of Inc. the National Hemophilia Foundation New England Hemophilia Association Arizona Hemophilia Association Hawaii Chapter--National Hemophilia Hawaii Chapter--National Hemophilia Foundation Foundation Hemophilia Foundation of Southern Arizona Hemophilia Association California Hemophilia of North Carolina Virginia Hemophilia Foundation Connecticut Hemophilia Society, Idaho Chapter of the National Inc. Hemophilia Foundation Hemophilia Association of New Bleeding Disorders Alliance of Jersey North Dakota Hemophilia Foundation of Oregon ------------------------------------------------------------------------ ------------------------------------------------------------------------ Payment amount Project name (in (USD)) Payment date ------------------------------------------------------------------------ Industry Symposium $7,500.00 3/13/2018 ------------------------------------------------------------------------ The Coalition for Hemophilia B 12th $20,000.00 3/14/2018 Annual Symposium ------------------------------------------------------------------------ 2018 HNC Walks in Charlotte & Raleigh $7,500.00 3/14/2018 ------------------------------------------------------------------------ Family Weekend $2,500.00 3/16/2018 ------------------------------------------------------------------------ Gainesville Clot Trot $2,500.00 3/17/2018 ------------------------------------------------------------------------ WVNHF Men's and Women's Day $3,000.00 3/20/2018 ------------------------------------------------------------------------ The Coalition for Hemophilia B 2018 $8,000.00 3/20/2018 Annual Sponsorship Run ------------------------------------------------------------------------ Big Red Run 2018 $1,500.00 3/20/2018 ------------------------------------------------------------------------ FAME Phoenix and Tucson $3,000.00 3/20/2018 ------------------------------------------------------------------------ Infusion Classes $1,000.00 3/20/2018 ------------------------------------------------------------------------ World Hemophilia Day $1,000.00 3/22/2018 ------------------------------------------------------------------------ Educations Days 2018 $5,000.00 3/22/2018 ------------------------------------------------------------------------ Northwest Arkansas Educational Day $1,500.00 3/22/2018 ------------------------------------------------------------------------ World Hemophilia Day $2,500.00 3/23/2018 ------------------------------------------------------------------------ Annual Meeting & Family Education $3,000.00 3/26/2018 Dinner ------------------------------------------------------------------------ Hill Country Family Education Day $1,000.00 3/26/2018 ------------------------------------------------------------------------ Southeast Texas Family Education Day $1,000.00 3/26/2018 ------------------------------------------------------------------------ Men's Retreat $2,500.00 3/26/2018 ------------------------------------------------------------------------ Texas Bleeding Disorders Conference $6,000.00 3/27/2018 Exhibit ------------------------------------------------------------------------ Texas Bleeding Disorders Conference $50,000.00 3/27/2018 ------------------------------------------------------------------------ Women and Bleeding Disorders $1,500.00 3/27/2018 Conference ------------------------------------------------------------------------ Family Education Day $2,500.00 3/27/2018 ------------------------------------------------------------------------ 8th Annual Walk in the Jungle $5,000.00 3/27/2018 ------------------------------------------------------------------------ Family Camp $1,000.00 3/28/2018 ------------------------------------------------------------------------ BDAI 2018 Statewide Family Education $2,500.00 3/28/2018 Weekend & World ------------------------------------------------------------------------ 2018 Bleeding Disorder Walk $1,000.00 3/28/2018 ------------------------------------------------------------------------ Camp HONOR $1,000.00 3/29/2018 ------------------------------------------------------------------------ Be A Factor 5 k $500.00 3/29/2018 ------------------------------------------------------------------------ Unite for Bleeding Disorders Health $2,500.00 3/30/2018 Fair ------------------------------------------------------------------------ Family Education Weekend $3,000.00 3/30/2018 ------------------------------------------------------------------------ Family Education Weekend $2,000.00 4/3/2018 ------------------------------------------------------------------------ Spring Wellness Program $1,500.00 4/4/2018 ------------------------------------------------------------------------ Teen Leadership Summit $1,000.00 4/4/2018 ------------------------------------------------------------------------ Family Information Day $5,000.00 4/4/2018 ------------------------------------------------------------------------ Annual Meeting $5,000.00 4/5/2018 ------------------------------------------------------------------------ Unite for Bleeding Disorders Walk $2,500.00 4/5/2018 ------------------------------------------------------------------------ Spring Social $1,500.00 4/5/2018 ------------------------------------------------------------------------ Victory for Women $2,800.00 4/5/2018 ------------------------------------------------------------------------ HFMD Annual Members Meeting $1,500.00 4/6/2018 ------------------------------------------------------------------------ HFM's 2018 National Conference for $100,000.00 4/6/2018 Women with Bleeding Disorders ------------------------------------------------------------------------ OHF Camp Independence $4,000.00 4/9/2018 ------------------------------------------------------------------------ Camp Clot Not $2,500.00 4/9/2018 ------------------------------------------------------------------------ 2018 CAF Care Walk $7,500.00 4/9/2018 ------------------------------------------------------------------------ 2018 ``Unite for Bleeding Disorders'' $2,500.00 4/9/2018 Health Fair and Walk ------------------------------------------------------------------------ 2018 Camp Globeclotters $2,500.00 4/9/2018 ------------------------------------------------------------------------ 2018 Camp Notaclotamongus $1,250.00 4/10/2018 ------------------------------------------------------------------------ Teen/Young Adult Program $15,000.00 4/10/2018 ------------------------------------------------------------------------ Annual State Educational Meeting $3,500.00 4/10/2018 ------------------------------------------------------------------------ Website ad and direct mailing $4,000.00 4/11/2018 ------------------------------------------------------------------------ Youth Leadership Weekend 2018 $500.00 4/11/2018 ------------------------------------------------------------------------ Camp Independent Firefly $1,000.00 4/11/2018 ------------------------------------------------------------------------ Utah Hemophilia Foundation's Family $2,000.00 4/11/2018 Resource Fair ------------------------------------------------------------------------ Camp Frozen Chozen $3,500.00 4/11/2018 ------------------------------------------------------------------------ HELLO- State Annual Meeting and $2,500.00 4/16/2018 Educational Conference ------------------------------------------------------------------------ 2018 Oregon Unite for Bleeding $2,500.00 4/16/2018 Disorders Walk ------------------------------------------------------------------------ 2018 Race for Ian $500.00 4/17/2018 ------------------------------------------------------------------------ 2018 48th Annual Meeting $3,000.00 4/17/2018 ------------------------------------------------------------------------ 17th Annual Family Education Program $2,800.00 4/19/2018 ------------------------------------------------------------------------ Camp Brave Eagle $1,500.00 4/19/2018 ------------------------------------------------------------------------ Race to Stop the Bleeding $4,000.00 4/19/2018 ------------------------------------------------------------------------ HFM Family Educational Dinner and $4,000.00 4/19/2018 Display Night ------------------------------------------------------------------------ Gears for Good Charity Bike Ride $1,000.00 4/19/2018 ------------------------------------------------------------------------ Colorado Family Camp 2018 $1,500.00 4/20/2018 ------------------------------------------------------------------------ Spanish Program: Greeley $1,000.00 4/20/2018 ------------------------------------------------------------------------ Family Camp $5,000.00 4/20/2018 ------------------------------------------------------------------------ Eighth Annual Center for Bleeding $1,500.00 4/20/2018 Disorders Conference ------------------------------------------------------------------------ 9th Annual Walk $10,000.00 4/20/2018 ------------------------------------------------------------------------ NYC Unite for Bleeding Disorders Walk $5,000.00 4/20/2018 2018 ------------------------------------------------------------------------ New Patient Summer Social $1,000.00 4/20/2018 ------------------------------------------------------------------------ The Coalition for Hemophilia B Fall $72,500.00 4/20/2018 Woman's Retreat ------------------------------------------------------------------------ Community Education Days $7,500.00 4/20/2018 ------------------------------------------------------------------------ Tampa Superhero Walk For Bleeding $2,500.00 4/20/2018 Disorders ------------------------------------------------------------------------ Western Washington Spring Education $1,500.00 4/20/2018 Day ------------------------------------------------------------------------ 2018 New Jersey Hemophilia Walk $4,000.00 4/23/2018 ------------------------------------------------------------------------ 7th Annual Hemophilia Awareness Walk $2,500.00 4/30/2018 ------------------------------------------------------------------------ 2018 Wisconsin Bleeding Disorders $4,000.00 5/1/2018 Conference ------------------------------------------------------------------------ Hemophilia Association Annual Meeting $5,000.00 5/15/2018 ------------------------------------------------------------------------ 2018 TexCen Annual Meeting and Summer $3,000.00 5/20/2018 Education Day ------------------------------------------------------------------------ Social Factor: Colorado Spring $1,000.00 5/21/2018 ------------------------------------------------------------------------ 2018 Industry Symposium $3,500.00 5/22/2018 ------------------------------------------------------------------------ 2018 Kentucky Unite for Bleeding $2,500.00 6/5/2018 Disorders Walk ------------------------------------------------------------------------ 2018 Annual Education Meeting $1,750.00 6/5/2018 ------------------------------------------------------------------------ 2018 KHF Camp Discovery--Summer Camp $2,000.00 6/5/2018 Program for Children and Teens ------------------------------------------------------------------------ Unite for Bleeding Disorders Walk $1,000.00 6/7/2018 ------------------------------------------------------------------------ WVNHF Industry Symposium $3,000.00 6/7/2018 ------------------------------------------------------------------------ 12th Annual Sickle Cell Disease $5,000.00 6/11/2018 Research and Educational ------------------------------------------------------------------------ FASEB Conference on ``Genome $2,000.00 6/13/2018 Engineering: Cutting-Edge ------------------------------------------------------------------------ 2018 Family Education Weekend $2,000.00 6/14/2018 ------------------------------------------------------------------------ Camp Klotty Pine 2018 $1,000.00 6/14/2018 ------------------------------------------------------------------------ Camp Blood Brothers and Sisters $2,000.00 6/17/2018 ------------------------------------------------------------------------ Family Education Conference $5,000.00 6/17/2018 ------------------------------------------------------------------------ 35th Annual Florida Bleeding Disorders $6,000.00 6/17/2018 Conference (Formerly known as the ``Family Education Symposium'') ------------------------------------------------------------------------ Familia de Sangre $50,000.00 6/18/2018 ------------------------------------------------------------------------ Northern Nevada Family Education Day $1,500.00 6/18/2018 ------------------------------------------------------------------------ Unite For Bleeding Disorders $1,000.00 6/18/2018 ------------------------------------------------------------------------ Union Latina (Latin Union) Educational $2,500.00 6/18/2018 Retreat ------------------------------------------------------------------------ Men's Educational Retreat $1,500.00 6/18/2018 ------------------------------------------------------------------------ 2018 Hemophilia of Indiana Annual $4,000.00 6/19/2018 Meeting ------------------------------------------------------------------------ 2018 Unite For Bleeding Disorders Walk $3,500.00 6/19/2018 ------------------------------------------------------------------------ Doug Thompson Teen Leadership Camp $1,500.00 6/19/2018 ------------------------------------------------------------------------ 2018 Teen Camp $2,000.00 6/20/2018 ------------------------------------------------------------------------ Hawaii Teen Summit $7,500.00 6/20/2018 ------------------------------------------------------------------------ OHF Annual Meeting 2018 $3,500.00 6/20/2018 ------------------------------------------------------------------------ Teen Adventure Camp $2,500.00 6/20/2018 ------------------------------------------------------------------------ Mile High Summer Camp 2018 $1,000.00 6/20/2018 ------------------------------------------------------------------------ Koko Ohana Family Camp $2,500.00 6/20/2018 ------------------------------------------------------------------------ RMHBDA Walk for Bleeding Disorders $1,500.00 6/21/2018 ------------------------------------------------------------------------ RMHBDA BIG SKY FAMILY CAMP $1,000.00 6/21/2018 ------------------------------------------------------------------------ Camp Youngblood--Summer Camp $1,000.00 6/21/2018 ------------------------------------------------------------------------ Summer Camp $1,000.00 6/21/2018 ------------------------------------------------------------------------ HACA Fall Festival and Walk $7,500.00 6/21/2018 ------------------------------------------------------------------------ Western Pennsylvania Walk, Run, and $2,000.00 6/21/2018 Cornhole Tournament ------------------------------------------------------------------------ Unite for Bleeding Disorders Walk $3,000.00 6/22/2018 ------------------------------------------------------------------------ COC-New Patient Orientstion $1,750.00 6/22/2018 ------------------------------------------------------------------------ BDAI 2018 Unite Walk for Bleeding $2,500.00 6/25/2018 Disorders Sponsorship ------------------------------------------------------------------------ Family Education Day $5,500.00 6/26/2018 ------------------------------------------------------------------------ Hike4HAM $2,500.00 6/27/2018 ------------------------------------------------------------------------ Women's Retreat $2,000.00 6/27/2018 ------------------------------------------------------------------------ Alaska Bleeding Disorder Walk--Exhibit $1,750.00 6/27/2018 ------------------------------------------------------------------------ FAMOHIO Annual Meeting and Educational $12,500.00 6/27/2018 Symposium ------------------------------------------------------------------------ Back to School Educational Event $2,500.00 6/28/2018 ------------------------------------------------------------------------ NHF 2018 Bleeding Disorders Conference $237,000.00 6/29/2018 Sponsorships ------------------------------------------------------------------------ MHA UNITE for Bleeding Disorders Walk- $2,500.00 7/2/2018 a-Thon ------------------------------------------------------------------------ 2018 Wisconsin Unite for Bleeding $5,000.00 7/2/2018 Disorders Walk ------------------------------------------------------------------------ ``In my Blood'' Bleeding Disorders $2,000.00 7/2/2018 Awareness Walk ------------------------------------------------------------------------ Camp Valor 2018 $6,000.00 7/2/2018 ------------------------------------------------------------------------ Superhero Run/Walk--Covington, LA $5,000.00 7/3/2018 ------------------------------------------------------------------------ Superhero HOPE Run/Walk--Wichita, KS $5,000.00 7/3/2018 ------------------------------------------------------------------------ WVNHF Family Camp $3,000.00 7/5/2018 ------------------------------------------------------------------------ Annual Meeting $1,500.00 7/5/2018 ------------------------------------------------------------------------ Kids Day Camp $7,000.00 7/6/2018 ------------------------------------------------------------------------ BLeaders Teen Retreat $5,000.00 7/15/2018 ------------------------------------------------------------------------ BITS AND PIECES OF Pediatric $1,000.00 7/16/2018 Hematology, Oncology & BM ------------------------------------------------------------------------ BBBDN Back to School Educating for $5,000.00 7/16/2018 Success ------------------------------------------------------------------------ Western Slope Social Factor $1,000.00 7/17/2018 ------------------------------------------------------------------------ Colorado Unite for Bleeding Disorders $1,500.00 7/17/2018 Walk ------------------------------------------------------------------------ ASH Corporate Friends $35,000.00 7/17/2018 ------------------------------------------------------------------------ Annual BDAST 2018 Hike Fundraiser $3,000.00 7/17/2018 ------------------------------------------------------------------------ Family Retreat $4,000.00 7/17/2018 ------------------------------------------------------------------------ NYCHC 2018 Women's Retreat $10,000.00 7/23/2018 ------------------------------------------------------------------------ National LadyBugs Womens Summit $50,000.00 8/2/2018 ------------------------------------------------------------------------ Hispanic Heritage Symposium $3,500.00 8/2/2018 ------------------------------------------------------------------------ UNITE for Bleeding Disorders Walk $2,500.00 8/2/2018 ------------------------------------------------------------------------ Women's Retreat $2,000.00 8/2/2018 ------------------------------------------------------------------------ 2018 Patient Advocacy Summit $33,000.00 8/7/2018 ------------------------------------------------------------------------ 2018 Finger Lakes Triathlon $5,000.00 8/7/2018 ------------------------------------------------------------------------ MHA Family Education Weekend-- $2,000.00 8/8/2018 Connecting the Bleeding ------------------------------------------------------------------------ Educational Family Camp and Adult $3,000.00 8/10/2018 Retreat ------------------------------------------------------------------------ NACCHO 2019 $180,000.00 8/13/2018 ------------------------------------------------------------------------ 46th Annual SCDAA National Convention $25,000.00 8/14/2018 ------------------------------------------------------------------------ HTRS Corporate Colleague--Sustaining $10,000.00 8/16/2018 Member ------------------------------------------------------------------------ Walk for Sickle Cell Disease $5,000.00 8/20/2018 ------------------------------------------------------------------------ Community Liaison Project $5,000.00 8/22/2018 ------------------------------------------------------------------------ 2018 HOPE Conference $15,000.00 8/23/2018 ------------------------------------------------------------------------ Unite for Bleeding Disorders 5K $2,500.00 8/28/2018 ------------------------------------------------------------------------ TORCH Teen Retreat $7,000.00 8/29/2018 ------------------------------------------------------------------------ Bilingual Back to School Event $5,000.00 8/29/2018 ------------------------------------------------------------------------ Hemophilia Association of New Jersey $2,500.00 8/29/2018 (HANJ) Fall Education ------------------------------------------------------------------------ Annual Statewide Meeting $10,000.00 8/29/2018 ------------------------------------------------------------------------ Unite for Bleeding Disorder Walk $1,000.00 9/4/2018 ------------------------------------------------------------------------ Fall Fam Jam $1,000.00 9/5/2018 ------------------------------------------------------------------------ Sickle CELLebration $3,000.00 9/5/2018 ------------------------------------------------------------------------ The Turkey Trot 5k Walk for Hemophilia $2,500.00 9/6/2018 and Bleeding Disorders ------------------------------------------------------------------------ Unite for Bleeding Disorder Walk $1,500.00 9/6/2018 ------------------------------------------------------------------------ Empowering Women with Bleeding and $3,500.00 9/7/2018 Clotting Disorders ------------------------------------------------------------------------ Blazin for Bleeders 5k/walk $1,000.00 9/7/2018 ------------------------------------------------------------------------ 2018 HFO Insurance Forum $3,000.00 9/7/2018 ------------------------------------------------------------------------ 2018 PACT Workshop $15,000.00 9/8/2018 ------------------------------------------------------------------------ 2018 Family Retreat/Annual Meeting $3,500.00 9/10/2018 ------------------------------------------------------------------------ Annual Meeting $1,500.00 9/10/2018 ------------------------------------------------------------------------ 2018 BDAN Fall Family Retreat $2,500.00 9/10/2018 ------------------------------------------------------------------------ Spokes Men for Bleeders $500.00 9/11/2018 ------------------------------------------------------------------------ Fall Fest $5,000.00 9/11/2018 ------------------------------------------------------------------------ WPCNHF'S Erie Educational Event $2,000.00 9/11/2018 ------------------------------------------------------------------------ Unite for Bleeding Disorders Walk $5,000.00 9/11/2018 ------------------------------------------------------------------------ Orlando Creepy Crawl 5K and Vampire $3,000.00 9/11/2018 Mile ------------------------------------------------------------------------ Jacksonville Creepy Crawl 5K and $3,000.00 9/11/2018 Vampire Mile ------------------------------------------------------------------------ Unite for Bleeding Disorders--Annual $2,500.00 9/17/2018 Walk ------------------------------------------------------------------------ Unite for Bleeding Disorders Walk $1,000.00 9/17/2018 ------------------------------------------------------------------------ TSBDF Annual Meeting $1,500.00 9/17/2018 ------------------------------------------------------------------------ Unite for Bleeding Disorders Walk $1,000.00 9/17/2018 ------------------------------------------------------------------------ Latino Retreat $10,000.00 9/17/2018 ------------------------------------------------------------------------ Spanish-Language Education Event $1,500.00 9/17/2018 ------------------------------------------------------------------------ Inaugural Health Fair $2,500.00 9/18/2018 ------------------------------------------------------------------------ 2018 Adult Retreat $1,500.00 9/19/2018 ------------------------------------------------------------------------ OHF Family Education Retreat $1,000.00 9/20/2018 ------------------------------------------------------------------------ Annual Meeting $2,000.00 9/21/2018 ------------------------------------------------------------------------ 42nd Annual Meeting and Educational $5,500.00 9/26/2018 Symposium ------------------------------------------------------------------------ Trick or Trot Family Walk $3,000.00 9/26/2018 ------------------------------------------------------------------------ Patient and Family Education Weekend $2,500.00 10/5/2018 ------------------------------------------------------------------------ 2018 Bleeding Disorders Conference $35,000.00 10/8/2018 Final Night Event ------------------------------------------------------------------------ Wichita Education Day $1,500.00 10/9/2018 ------------------------------------------------------------------------ Winter Education Meeting and Holiday $3,500.00 10/9/2018 Festival ------------------------------------------------------------------------ 8th Annual Unite for Bleeding $2,500.00 10/9/2018 Disorders Walk and Fun Race ------------------------------------------------------------------------ Family Education Day $2,500.00 10/11/2018 ------------------------------------------------------------------------ COC-Education Retreat $3,250.00 10/11/2018 ------------------------------------------------------------------------ Eastern Washington Annual Meeting 2018 $1,500.00 10/11/2018 ------------------------------------------------------------------------ Nebraska Industry Symposium $5,000.00 10/16/2018 ------------------------------------------------------------------------ The Coalition for Hemophilia B $3,000.00 10/16/2018 Meetings on the Road ------------------------------------------------------------------------ NOHF Annual Education Meeting $5,500.00 10/16/2018 ------------------------------------------------------------------------ Annual Meeting $3,000.00 10/17/2018 ------------------------------------------------------------------------ Camp Harvest $6,000.00 10/18/2018 ------------------------------------------------------------------------ Issues and Challenges in the $2,500.00 10/22/2018 Management of Hemophilia ------------------------------------------------------------------------ Steven Margolies, MD Family $6,000.00 10/22/2018 Educational Conference ------------------------------------------------------------------------ 2018 TexCen Chapter Winter Education $3,000.00 11/1/2018 Day ------------------------------------------------------------------------ NYCHC Annual Education Day $7,500.00 11/2/2018 ------------------------------------------------------------------------ TSBDF Education Dinner $2,000.00 11/5/2018 ------------------------------------------------------------------------ Winterfest $1,500.00 11/6/2018 ------------------------------------------------------------------------ Annual Family Conference $2,250.00 11/19/2018 ------------------------------------------------------------------------ Holiday Educational Program $2,000.00 12/6/2018 ------------------------------------------------------------------------ College and Career Fair $1,500.00 12/11/2018 ------------------------------------------------------------------------ ASGCT Patient Education Videos $5,000.00 12/13/2018 ------------------------------------------------------------------------ The Coalition for Hemophilia B Patient $10,000.00 12/18/2018 Survey ------------------------------------------------------------------------ Advocacy Training $2,500.00 12/18/2018 ------------------------------------------------------------------------ Grassroots Advocacy Project $5,000.00 12/19/2018 ------------------------------------------------------------------------ State Advocacy Training $500.00 1/3/2019 ------------------------------------------------------------------------ Annual Silver-level Corporate $15,000.00 1/4/2019 Sponsorship ------------------------------------------------------------------------ Annual Meeting and Family Educational $10,000.00 1/7/2019 Dinner ------------------------------------------------------------------------ TSBDF Winter Program-Journey Around $1,500.00 1/7/2019 the World ------------------------------------------------------------------------ 4th Annual Industry Forum $5,000.00 1/11/2019 ------------------------------------------------------------------------ Advocacy Education and Training $5,000.00 1/15/2019 Seminar ------------------------------------------------------------------------ Latino Group Weekend 2019 $1,500.00 1/16/2019 ------------------------------------------------------------------------ Winter Education Day 2019 $1,500.00 1/16/2019 ------------------------------------------------------------------------ RMHBDA EDUCATION WEEKEND AND ANNUAL $2,000.00 1/16/2019 MEETING ------------------------------------------------------------------------ New England Hemophilia Association $1,500.00 1/16/2019 Winter Camp ------------------------------------------------------------------------ Purpose Driven Leadership Program $2,500.00 1/16/2019 ------------------------------------------------------------------------ Maryland Advocacy Days $5,000.00 1/21/2019 ------------------------------------------------------------------------ WPCNHF's New Parent Network $4,000.00 1/21/2019 ------------------------------------------------------------------------ WPCNHF's Semi-Annual Education Weekend $5,000.00 1/21/2019 ------------------------------------------------------------------------ Men In Action/Infusing Love Group's $1,500.00 1/21/2019 Valentine Event ------------------------------------------------------------------------ Medial Symposium $5,000.00 1/21/2019 ------------------------------------------------------------------------ Women's Retreat $5,000.00 1/21/2019 ------------------------------------------------------------------------ emPOWERment Forum $2,500.00 1/22/2019 ------------------------------------------------------------------------ 2018 Corporate Program Sponsorship-- $1,875.00 2/4/2019 Silver ------------------------------------------------------------------------ Four Bioverativ Branded Educational $1,250.00 2/4/2019 Dinners ------------------------------------------------------------------------ WPCNHF's New Parent Network $1,000.00 2/4/2019 ------------------------------------------------------------------------ Consumer Medical Symposium $3,000.00 2/12/2019 ------------------------------------------------------------------------ Zoo Walk 2019 $4,000.00 2/12/2019 ------------------------------------------------------------------------ Hawaii Future Leaders $2,500.00 2/13/2019 ------------------------------------------------------------------------ Hawaii Ohana Education Weekend 2019 $7,500.00 2/13/2019 ------------------------------------------------------------------------ Women's Retreat $3,500.00 2/13/2019 ------------------------------------------------------------------------ Bleeding Disorder Awareness Kick Off $1,500.00 2/13/2019 ------------------------------------------------------------------------ 2019 Annual Meeting $2,000.00 2/13/2019 ------------------------------------------------------------------------ Teen--Young Adult Program $15,000.00 2/13/2019 ------------------------------------------------------------------------ 15th Annual CHS Alpine Walk $2,000.00 2/20/2019 ------------------------------------------------------------------------ Victory for Women $2,800.00 3/7/2019 ------------------------------------------------------------------------ Winter Membership Gathering $5,000.00 3/7/2019 ------------------------------------------------------------------------ 2019 Annual Meeting $3,000.00 3/13/2019 ------------------------------------------------------------------------ YETI--Youth Effectively Transitioning $5,000.00 3/18/2019 to Independence ------------------------------------------------------------------------ 2015 SANOFI US ------------------------------------------------------------------------ Legal Name Project Title Payment Amount ------------------------------------------------------------------------ A R M S Inc. Homecoming & Project Little $5,000.00 Soldier Academy of Managed Improving patient outcomes and $45,000.00 Care Pharmacy management of hyperlipidem ACS Organic Chemistry Graduate Research Symposium $1,000.00 Division AHIP Foundation Executive Leadership Program $55,000.00 Alabama Kidney 2015 Huntsville Kidney Walk $1,000.00 Foundation Alabama Kidney 2015 Birmingham Kidney Walk $1,000.00 Foundation Alabama Kidney Dothan Kidney Walk $1,000.00 Foundation Albany American Saratoga Springs Tour de Cure $5,000.00 Diabetes Association ALL IN TOGETHER All in Together Campaign: $37,500.00 CAMPAIGN INC. Advancing and Empowering Women Allergy & Asthma US Anaphylaxis Summit $30,000.00 Network Mothers of Asthmatics Allergy & Asthma AAP Anaphylaxis Champions $100,000.00 Network Mothers of Program Asthmatics Allergy & Asthma Allergy & Asthma Day Capitol $50,000.00 Network Mothers of Hill 2015 Asthmatics Alliance For A Alliance for a Healthier $25,000.00 Healthier Generation Generation Inc. Alliance for Aging 2015 Aging in Motion Coalition $15,000.00 Research Amerian Diabetes American Diabetes Association $2,500.00 Association Diabetes Health and Wellness Expo American Academy of American Academy of Pediatrics $35,000.00 Pediatrics-Key Cards Key Card Sponsorship AMERICAN ASSOCIATION 2015 AACR Annual Meeting MICR $10,000.00 FOR CANCER RESEARCH Networking and Resource Center AMERICAN ASSOCIATION 2015 AACR Network Hubs $25,000.00 FOR CANCER RESEARCH Sponsorship American Cancer ACS CAN Seattle Research $2,500.00 Society Breakfast and ACS CAN advocacy activities American Cancer ACS CAN CA Research Events and $5,000.00 Society ACS CAN advocacy activities American Cancer ACS CAN's advocacy activities $1,500.00 Society in Arkansas and nationwide American Cancer ACS CAN Virginia Research $1,000.00 Society Breakfast and advocacy activities American Cancer ACS CAN's advocacy activities $1,000.00 Society in Louisiana and nationwide American Cancer ACS CAN Mississippi Health $1,000.00 Society Forum and ACS CAN advocacy activities American Cancer ACS CAN Iowa Research Event and $2,000.00 Society ACS CAN advocacy activities American Cancer 2015 Minnesota Policy Breakfast $1,000.00 Society and ACS CAN advocacy activities American Cancer 2015 Oklahoma Policy Forums $750.00 Society American Cancer 2015 Pennsylvania Advocacy $1,000.00 Society Event American Cancer 2015 Maryland Advocacy $1,000.00 Society Breakfast American Cancer Gemson Awards $2,500.00 Society American Cancer Nationwide Hope Lodge $25,000.00 Society Inc. Partnership American Chemical Division of Medicinal Chemistry $2,500.00 Society Division of Program 250th ACS national me Medicinal Chemistry American College of American College of Allergy, $53,000.00 Allergy, Asthma & Asthma & Immunology FIT Bowl Immunology-FIT Bowl American College of 2015 Patient Engagement $25,000.00 Cardiology Pavilion American College of Sanofi/Regeneron Meeting $10,412.60 Cardiology American College of Moving to the Quadruple Aim: $280,369.00 Physicians, Inc. ACP Quality Connect: Diabetes American Diabetes Step Out: Walk to Stop Diabetes $5,000.00 Assocation American Diabetes Central Iowa Tour de Cure $5,000.00 Association American Diabetes Tour de Cure Southeast $1,500.00 Association Wisconsin (Grafton) American Diabetes Tour de Cure Madison $1,500.00 Association American Diabetes 2015 American Diabetes $2,000.00 Association Association--WI Gala American Diabetes Father of the Year/Camp Sugar $2,000.00 Association Falls American Diabetes Father of the Year Awards $5,000.00 Association American Diabetes Stop Diabetes Through Advocacy $2,000.00 Association Workshop American Diabetes Boston Step Out Walk to STOP $5,000.00 Association Diabetes American Diabetes Central MA Step Out Walk to $5,000.00 Association STOP Diabetes American Diabetes 2015 Kiss a Pig Gala $2,500.00 Association American Diabetes 2015 Rochester Tour de Cure $2,500.00 Association American Diabetes Step Out: Walk to Stop Diabetes $5,000.00 Association American Diabetes Portland Father of the Year $2,500.00 Association Awards Dinner American Diabetes Jim Hansen, MD Memorial $3,500.00 Association Symposium Series American Diabetes St. Louis Tour de Cure $500.00 Association American Diabetes Diabetes Awareness and $50,000.00 Association Intervention--via Step Out: Walk to St American Diabetes 2015 World Diabetes Day $5,000.00 Association American Diabetes 75th Anniversary & Awards $50,000.00 Association Celebration American Diabetes Step Out Walk to STOP Diabetes $2,500.00 Association American Diabetes American Diabetes Expo--Exhibit/ $57,000.00 Association Expo- Speaker/Booth Signage/Program Exhibit/Speaker/ BoothSignage/Program AMERICAN DIABETES Diabetes Hospitality Days: Stop $75,000.00 ASSOCIATION INC. Diabetes In Boston AMERICAN DIABETES 2015 Pathways to Stop Diabetes $2,500,000.00 ASSOCIATION INC. AMERICAN DIABETES Step Out: Walk to Stop Diabetes $5,000.00 ASSOCIATION INC. AMERICAN DIABETES Step Out: Walk to Stop Diabetes $2,500.00 ASSOCIATION INC. AMERICAN DIABETES Father of the Year Awards Gala $5,000.00 ASSOCIATION INC. American Diabetes 2015 Tour de Cure $5,000.00 Association, Indiana Indiana American Diabetes ADA Indiana's Josiah Kirby $15,000.00 Association, Indiana Lilly Sr. Distinguished Service Award American Diabetes Father of the Year Gala $5,000.00 Associaton American Heart AMERICAN HEART ASSOCIATION-- $75,000.00 Association MOBILE APP American Heart 2015 Walking Challenge $100,000.00 Association American Heart American Heart Association $50,000.00 Association Advertising Space (Key Cards) American Heart 2015 Heart Innovation Forum $15,000.00 Association American National Red 2015-2016 General Blood $25,000.00 Cross Services Support and High School Sc American Pharmacists Emerging Insulins $79,000.00 Association American Society for Second Regional Bone Marrow $12,700.00 Blood and Marrow Transplant conference for Transplantation Nurses American Society of 2015 ASN Abstract CD $80,000.00 Nephrology Sponsorship American Society of 2015 Sponsorship Opportunities $50,000.00 Transplantation Americares Foundation US Disaster Assistance $10,000.00 Inc. America's Health CMO Roundtable $45,000.00 Insurance Plans APhA Foundation Primary Care and Patient $249,550.00 Empowerment through Diabetes Patie Arizona Diabetes Diabetes: A Prescription for $5,000.00 Foundation Care Arrow Lake Foundation Arrow Lake Foundation $50,000.00 Activities Plan Arthritis Foundation Research Update Events $10,000.00 Northeast Region, Inc. Arthritis Foundation Advocacy Program and Advocacy $15,000.00 Northeast Region, Training Series Inc. Association for IQ/AAALAC International Global $5,000.00 Assessment and 3Rs Awards Accreditation of Laboratory Animal Ca Association of 32 National Oncology Conference $50,000.00 Community Cancer Centers Association of 2015 Membership Dues $6,250.00 Corporate Contributions Professionals Asthma & Allergy Advocacy Day $1,000.00 Foundation of America, St. Louis Chapter Asthma & Allergy Allertrain Master Trainer $1,500.00 Foundation of Program America, St. Louis Chapter Asthma and Allergy 2015 KFA Anaphylaxis Patient $33,000.00 Foundation of America Education Asthma and Allergy 2015 Anaphylaxis Awareness $250,000.00 Foundation of America Campaign ASTS Foundation ASTS Program Support $75,000.00 Autoimmune Advocacy Living with Autoimmunity--3 $2,500.00 Alliance separate events Bay Area Association Help! I Just Learned I have $1,200.00 of Kidney Patients Chronic Kidney Disease! What do I do? Bay Area Bioscience CALBIO 2015 $10,000.00 Association Baylor Health Care STEEEP Academy Lectureship $135,000.00 System Foundation Series Be The Match Quick Reference Guidelines-- $90,000.00 Foundation Transplant Consultation and Post-Transplant BHCAG FOUNDATION MNBTE Recognition Event $5,000.00 Bill, Hillary, and Program Support--CHMI $100,000.00 Chelsea Clinton Foundation Bill, Hilary, and National Health Transformation $50,000.00 Chelsea Clinton Foundation Biocom Global Life Science Partnering $10,000.00 Conference BIONJ INC. Bio NJ Sponsorship event $10,000.00 BIONJ INC. BIONJ INC. BioPartnering $3,000.00 BIONJ INC. CEO Summit $7,500.00 Blood and Marrow Survivorship Symposium Pre-Plan $5,000.00 Transplant Information Network Blood and Marrow Ask the Multiple Myeloma Expert $7,500.00 Transplant Information Network Blood and Marrow Transplant 101: An introduction $7,500.00 Transplant to hematopoietic cell Information Network transplant Blood and Marrow Caregiver 101: The Role of $7,500.00 Transplant Caregiver in Support of Bone Information Network Marrow Blood and Marrow Enhancing the Power of Peer $7,500.00 Transplant Support Information Network Blood and Marrow BMT InfoNet Web Site Redesign-- $75,000.00 Transplant Phase 1 Information Network Bringing Hope Home General Operating Support $10,000.00 Inc. Buffalo American Buffalo Niagara Tour de Cure $5,000.00 Diabetes Association Cambridgeport 2015 Summer Programs at $5,000.00 Neighborhood Magazine Beach Park Association, Inc. Camp Nejeda Foundation Helping Children with type 1 $20,000.00 diabetes live happier, healthier lives Cancer Resource Boston Prostate Cancer Walk Run $5,000.00 Foundation Cancer Support Celebration of Hope: A Free, $5,000.00 Community Greater Full-Day, Educational and Philadelphia Inspirational Cardio Renal Society Path to Wellness National Pilot $100,000.00 of America Center for Healthcare Diversity, Inclusion, & Life $9,500.00 Innovation Sciences Symposium Central New Jersey Leaders of Tomorrow (LOT) $10,000.00 Chapter Of The Program National Black Mba Association CEO Roundtable On Project Data Sphere initiative $1,000,000.00 Cancer, Inc. Chicago Hispanic Vive tu Vida/Get Up! Get $1,000.00 Health Coalition Moving! Health and Wellness Fair Children with Diabetes Platinum Sponsorship--Children $75,000.00 With Diabetes--Friends for Life Children with Diabetes Gold Level sponsorship of the $100,000.00 Children with Diabetes Friends for Life Childrens Inn At NIH Sanofi US Legacy Endowment Fund $1,000,000.00 Inc. at The Children's Inn at NIH Children's Medical Food Allergy Camp $5,000.00 Center Foundation Chordoma Foundation New York Regional Chordoma $2,500.00 Community Conference Chris4Life Colon 5th Annual Blue Hope Bash $3,000.00 Cancer Foundation Christ the King Prep Corporate Work Study Program $57,000.00 Cleveland Clinic Advances in Organ $134,276.00 Transplantation--Annual Fellows Conference CNY American Diabetes 2015 CNY Tour de Cure $4,000.00 Association Coastal Area Health Community Health Worker Core $25,000.00 Education Center Inc. Consensus (C3) Project Colon Cancer Alliance Blue Star Concert $1,000.00 Committee Encouraging 2015 Membership Dues $15,000.00 Corporate Philanthropy Community Oncology 2015 Community Oncology Payer $25,000.00 Alliance Exchange Summit III Oncology Conquer Cancer Fdn Of Conquer Cancer Foundation $50,000.00 The American Society General Mission Support Of Clinical Oncology Council on Foundations 2015 Membership Dues $15,000.00 CT Coalition for Organ Premier Charity of the Hartford $1,500.00 and Tissue Donation, Marathon dba, Donate Life Connect Dallas Fort Worth DFWBGH 11th Annual Benefits $5,000.00 Business Group on Forum Health DaVita Village Trust 2015 Tour DaVita $2,500.00 Deirdre O Brien Child Clinical Counseling Program $10,000.00 Advocacy Center Inc. Diabetes Care and DCE NewsFlash and 2 e-Blasts $21,500.00 Education with the Academy of Nutrition and Diete Diabetes Education and 2015 Industry Partners Advisory $15,000.00 Camping Association Council (IPAC) Diabetes Foundation Dancing for Diabetes Awards $10,000.00 Inc. Dinner Diabetes Hands Online Community for People $12,500.00 Foundation with Diabetes Diabetes Hands DHF--Hero Sponsorship $25,000.00 Foundation DiabetesSisters 2015 DiabetesSisters' PODS $20,000.00 Meetup Program Diplomacy Matters Spotlighting Humanitarian $2,500.00 Institute Innovation & Patents for Humanity Direct Relief Auvi-Q epinephrine injections $75,000.00 for students throughout California Direct Relief U.S. Hurricane/All Hazards $10,000.00 preparedness Program Employers Health Employer Health 2015 Annual $6,500.00 Coalition, Inc. Symposium Epilepsy Foundation of Parent Advocacy toolkit $8,000.00 NC Federal Circuit Bar Global Series: 2015 Shanghai $10,000.00 Association Conference Charitable and Educational Fund Federation of Clinical FOCIS 2015 Annual Meeting $14,500.00 Immunology Societies Fight Colorectal Patient Resource Guide for $5,000.00 Cancer Stage III and IV Finger Lakes American 2015 Finger Lakes Tour de Cure $4,000.00 Diabetes Association Florida Health Care Seeking Value in Cancer Care $5,000.00 Coalition Florida Health Care Health Care Purchasers as $7,500.00 Coalition Consumers: Smart Shopping for Health Care Food Allergy & FAACT Education Programs $150,000.00 Anaphylaxis Connection Team Food Allergy Research FARE National Food Allergy $25,000.00 Education Conference Food Allergy Research FARE Teen Summit $25,000.00 Education Food Allergy Research THE FOOD ALLERGY BALL $25,000.00 Education Food Allergy Research FAREWalk for Food Allergies $200,000.00 Education Food Bank of Somerset Back Pack Program $5,000.00 County Inc. Foundation for FBR Educational Programs--Bench $10,000.00 Biomedical Research to Bedside, Social Ambassadors Foundation For Prader Multiple Projects $1,000.00 Willi Research Fundacion Centro Diabetes Summer Camp 2015 $10,000.00 Pediatrico de Diabetes Fundacion Centro XIV Gala $3,500.00 Pediatrico de Diabetes Fundacion Centro 8th World Diabetes Month $5,000.00 Pediatrico de Celebration Diabetes Garden State Equality Teach and Affirm Students in $2,500.00 Education Fund Inc. New Jersey Global Healthy Living Managed Care Organization $24,000.00 Foundation Education (Overview) Gordon Research Gordon Research Atherosclerosis $20,000.00 Conference Meeting Governors Books From Tennessee's Imagination Library $2,500.00 Birth Foundation Program Greater New England Economic Development $4,000.00 Minority Supplier Development Council Health Action Council Annual Conference $4,200.00 Healthcare Woman of the Year $18,150.00 Businesswomen's Association HEART OF FLORIDA SP 2014 United Way Campaign $2,269.50 UNITED WAY Payout Heart To Heart US Crisis Readiness & Response $10,000.00 International Inc. Idaho Immunization Immunization Summit $2,000.00 Coalition Illinois Diabetes Illinois Diabetes Caucus $3,500.00 Caucus Foundation Foundation Illinois Business Day & Annual Lunch $1,000.00 Manufacturers' Sponsorships Association International Chinese 2015 International Chinese $2,000.00 Statistical Statistical Association (ICSA)/ Association Graybi International Eczema International Eczema Council $100,000.00 Council International Isotope Sponsorship of 12th $3,250.00 Society, Inc. International Symposium on the Synthesis International Myeloma 9th Annual Comedy Celebration $5,000.00 Foundation benefiting the Peter Boyle Research Fund International Myeloma 6th Annual International $35,000.00 Foundation Myeloma Working Group Summit International Myeloma Patient Programs 2015 $100,000.00 Foundation International Society RSG DREAM Conference $10,000.00 for Computational Biology International Society 25th ISHC Congress $1,000.00 of Heterocyclic Chemistry International Society ACoP6 $5,000.00 of Pharmacometrics JDRF Imagine Gala $100,000.00 JDRF JDRF One Walk Philadelphia and $2,500.00 Bucks County JDRF JDRF One Walk $7,500.00 JDRF JDRF Central AR One Walk $2,500.00 JDRF--Eastern PA JDRF One Walk Moosic, Poconos, $2,500.00 Chapter Lehigh Valley and Berks County JDRF Greater Dallas JDRF One Walk, Dallas $2,500.00 JDRF International JDRF One Walk Boston 2015 $10,000.00 JDRF International JDRF OneWalk $5,000.00 JDRF International JDRF Research Updates $2,000.00 Jefferson University Quality and Safety Leadership $100,000.00 (School of Population Series Health) Jefferson University Supporting Patient Access to $79,700.00 (School of Population Diabetes Care: Follow-on to Health) Janua Jersey Battered Womens Vocational Development Program $5,000.00 Service Joslin Diabetes A Taste of Ginger $25,000.00 Center, Inc. Joslin Diabetes National Diabetes Month/High $50,000.00 Center, Inc. Hopes Gala Juvenile Diabetes Rock the Cure $1,000.00 Research Foundation Kean University 2015 Group Summer Scholars $15,000.00 Foundation Inc. Research Program Keystone Symposia on Cancer Immunotherapy: Immunity $25,000.00 Molecular and and Immunosuppression Meds Cellular Biology Kidney Health Alliance Share Your Spare 5k for Get $750.00 of KY Healthy Get Transplanted Kids Corporation li Kids Corp General Operating $10,000.00 Lagrant Foundation Internship Program $25,000.00 Large Urological Group LUGPA Annual Meeting Gold Level $85,000.00 Practice Association Membership LUGPA Leukemia & Lymphoma Man & Woman of the Year $3,500.00 Society Living Well Cancer General Operating Support $2,500.00 Resource Center MA Conference for MA Conference for Women $20,000.00 Women Inc. Map International United States Disaster Relief $10,000.00 March of Dimes Supporting NICU Babies and $86,000.00 Foundation Families Maryland Health Care Specialty Rx Forum $7,500.00 Coalition DBA MidAtlantic Business Group on Health Care Massachusetts Annual Conference. Payment $2,000.00 Association of Health Reform--Three Years Later Plans MedStar Washington MedStar Washington Medical $3,000.00 Hospital Center Center--Current Issues in the Care Mended Hearts Patient Advocacy Network $100,000.00 Mended Hearts 2015 Mended Hearts National $50,000.00 Education and Training Conference Michigan Biosciences MichBio Conference Description $1,500.00 Industry Association Mid Atlantic Lifespan, Senior Care Providers $4,000.00 Inc. Roundtables With Local Hospitals Midland Adult Services Midland Meals on Wheels $10,000.00 Inc. Employment Training Program Migrant Clinicians Health Champions: Reducing $500.00 Network Disease to Improve Health Milken Institute The Research Acceleration and $10,000.00 Innovation Network (TRAIN) Milken Institute 2015 Milken Institute $1,000,000.00 Conference Sponsorships & Engagement Minnesota Society of MSHP Corporate Sponsorship $6,000.00 Health-System Pharmacists MIT 13th US-Japan Symposium on Drug $7,000.00 Delivery Systems MIT 14th Annual Koch Institute $5,000.00 Summer Symposium ``CANCER COMMITTEE'' MIT $100K Competition MIT $100K Competition $25,000.00 Multiple Myeloma Advances in Minimal Residual $25,000.00 Research Foundation Disease Testing in Myeloma Multiple Myeloma Advances in Minimal Residual $25,000.00 Research Foundation Disease Testing in Myeloma NATIONAL ACADEMY OF Forum on Drug Discovery, $85,000.00 SCIENCES Development and Translation National Alliance of 11th Annual Meeting $5,000.00 State Prostate Cancer Coalitions National Arbor Day Chippewa National Forest tree $4,138.00 Foundation planting National Association Childhood Obesity $10,000.00 for the Advancement of Colored People National Committee for NCQA's 25th Anniversary $10,000.00 Quality Assurance (``NCQA'') National Consumers Health Policies for Better $5,000.00 League Outcomes and Balanced Budgets National Eczema The Decade of Eczema: Roadmap $200,000.00 Association to Advocacy National Forum for 13th Annual Meeting of the $25,000.00 Heart Disease and National Forum for Heart Stroke Prevention Disease and Stoke Prevention Inc. National Foundation TB Trials Consortium $671,292.00 For The Ctrs For Disease Contr & Prevention Inc. National Health Voluntary Health Leadership $20,000.00 Council Conference National Health Policy Development Fund $70,000.00 Council National Kidney Patient Empowerment Workshop $2,000.00 Foundation National Kidney Kansas City Kidney Walk $1,000.00 Foundation National Kidney Wichita Kidney Walk $250.00 Foundation National Kidney 2015 Boston Kidney Walk $15,000.00 Foundation National Kidney Champion of Hope Tribute Dinner $1,000.00 Foundation of Michigan National Kidney Gift of Life Gala $1,500.00 Foundation of West Tennessee National Kidney NKF of West Tennessee Wolf Mash $250.00 Foundation of West Dash 5K Tennessee National Kidney 2015 New York City Kidney Walk $25,000.00 Foundation, Inc. National Kidney NKF Cares 2015 $25,000.00 Foundation, Inc. National Kidney NKF Peers 2015 $25,000.00 Foundation, Inc. National Kidney Eight Annual Mid-Atlantic First $5,000.00 Foundation, Inc. Year Renal Fellowship Symposium National Kidney 7th Annual Central New Jersey $1,000.00 Foundation, Inc. Kidney Walk National Kidney Philadelphia Kidney Walk $500.00 Foundation, Inc. National Kidney Chester County Kidney Walk $500.00 Foundation, Inc. National Kidney Wilmington Kidney Walk $500.00 Foundation, Inc. National Kidney Pittsburgh Kidney Walk $500.00 Foundation, Inc. National Kidney Northeast Ohio Kidney Walk $1,000.00 Foundation, Inc. Serving Ohio National Kidney 2015 Patient Symposium $1,000.00 Foundation, Inc. Serving Ohio National Patient NPAF Policy Consortium $20,000.00 Advocate Foundation National Press Training Journalists on $40,000.00 Foundation Advances in Biologics and Biosimilars National TB 2015 National TB Conference: $500.00 Controllers Sponsorship Request Association National Transitions National Transition of Care $250,000.00 of Care Coalition Coalition NBCH Hypoglycemia Action Brief $17,500.00 NBCH Annual Conference $3,500.00 NBCH ASCVD Action Brief $17,500.00 NCOMS NC Oncology Management Society $5,000.00 NEHI New Policy: Better Use of $25,000.00 Medicines in Diabetes Neuropathy Action 9th Annual ``Neuropathy Action $2,500.00 Foundation Awareness Day'' New Jersey Hall of Mobile Museum $2,500.00 Fame New Jersey Public NJPHA Sponsorship $5,000.00 Health Association New York Stem Cell NYSCF 10th Annual Translational $2,000.00 Foundation, Inc. Stem Cell Research Conference NJ SEEDS College Scholars Program $10,000.00 North Coast Health Celebration of Caring $2,500.00 Northeast Business eValue8 - Health Plan $9,000.00 Group on Health Performance Review Northeast Business Specialty Pharmacy Conference $5,000.00 Group on Health Northeastern Section German Exchange Program $2,000.00 of the American Chemical Society NSHMBA Foundation NSHMBA New Jersey Annual $5,000.00 Partnership Oklahoma Center for The transformation of $3,500.00 Healthcare Healthcare Improvement Opportunity Through Arizona Pavilion at BIO 2015 $1,000.00 Entrepreneurship Foundation Organization for OFII Annual Dinner $15,000.00 International Investment Partnership For 2016 Membership Dues $19,000.00 Quality Medical Donations Patient Advocate Prostate and CRC Co-Pay Relief $550,000.00 Foundation Fund PATIENT EMPOWERMENT The Latest News on Advanced $20,000.00 NETWORK Prostate Cancer Research and Treatment PCMA 2015 sPCMA Business Forum $60,000.00 Sponsorship PCMA 2015 Annual Meeting $75,000.00 Presidential Sponsorship Pediatric Cancer NHL 2015 Pediatric Sponsorship $10,000.00 Research Foundation Pennsylvania CBO Dinner $5,000.00 Biotechnology Association Perimeter Bicycling 2015 El Tour de Tucson $15,000.00 Association of America, Inc. Pharmaceutical PhRMA Foundation Grants and $100,000.00 Research and Fellowships Manufacturers of America Foundation Premier Cares Premier Cares Foundation $1,500.00 Foundation Prostate Cancer Walk Preventive Cholesterol Patient Education $100,000.00 Cardiovascular Nurses Association PRIDE PRIDE Conference $6,000.00 Project Hope The Responding to the Nepal $10,000.00 People To People Earthquake Health Foundation Inc. Prostate Cancer 22nd Annual Scientific Retreat $300,000.00 Foundation Raritan Valley Galileo Scholarships: Providing $17,500.00 Community College Access to STEM Education Foundation Raritan Valley Preparing for the Next $10,000.00 Community College Generation Science Standards Foundation Regents of the V-BID Summit 2015: A Decade of $40,000.00 University of Transforming the Health Care Michigan Renal Support Network KidneyTalk Podcast $1,000.00 Renal Support Network Live & Give Newsletter $1,500.00 Renal Support Network CKD Patient Education Meetin $1,500.00 Renal Support Network 13th Annual Patient Essay $1,000.00 Contest Resource Center of Transitional Housing Program $5,000.00 Somerset Inc. Rutgers University Vets 4 Warriors $10,000.00 Foundation RVCC Foundation STEM Education: Equity Issues $10,000.00 and Workforce Pipeline RVCC Foundation College Campus Experience Day $3,000.00 for STEM High School Students Sage Bionetworks 2015 Paris Assembly $15,000.00 Sanofi US Matching Sanofi US Matching Gifts--Q2 $277,628.31 Gifts--2015 2015 Sanofi US Matching Sanofi US Matching Gifts--Q1 $427,531.29 Gifts--2015 2015 SARSEF-SOUTHERN The Future of Biomedical $5,000.00 ARIZONA RESEARCH Research SCIENCE AND ENGINEERING Scripps Translational The Future of Genomic Medicine $10,000.00 Science Institute VIII Society of Toxicologic 2015 ACVP/ASVCP/STP Combined $2,500.00 Pathology Annual Meeting Society of Toxicology Society of Toxicology Annual $10,000.00 Meeting Somerset County SCBP 2015 program of work $20,000.00 Business Partnership Somerset Medical Fun 'N Fit $25,000.00 Center Foundation Inc. Somerset Medical EMS Program $5,000.00 Center Foundation Inc. Somerset Medical El Poder Sobre La Diabetes $10,000.00 Center Foundation Inc. South Dakota Diabetes Virtual Nurse Model: School $5,100.00 Coalition Project St. Louis Children's Food Allergy Management and $75,000.00 Hospital Foundation Education Stop Hunger Now Inc. Stop Hunger Now Program $10,000.00 Expansion to New York City Metro Stowe Weekend of Hope Stowe Weekend of Hope $5,000.00 T. Leroy Jefferson 2015 Community Health Fair $2,500.00 Medical Society Taking Control of Your The 9th Annual Diabetes Forum $10,000.00 Diabetes Tennessee Kidney 2015 Gift of Life Walk/5K $2,000.00 Foundation Tennessee Kidney Spring Soiree 2015 $2,500.00 Foundation Teratology Society Teratology Society 55th Annual $1,500.00 Meeting The American Major Symposia--Roots and $10,000.00 Association of Mechanisms of Human Autoimmun Immunologists, Inc. The American College ACVP/ASVCP/STP Combined Annual $6,000.00 of Veterinary Meeting Pathologists The American Fallen Portrait Sponsorship $25,000.00 Soldiers Project Inc. The American Kidney A Pairing for Prevention 2015 $5,000.00 Fund, Inc. The American Kidney The Hope Affair 2015 $50,000.00 Fund, Inc. The American Kidney 9th Annual New York Spring $1,500.00 Fund, Inc. Event The Bus Stops Here Hall Of Fame Induction for $35,000.00 Foundation Jerome Bettis The Center For Great Adult Women's Program $10,000.00 Expectations Inc. The Childrens Health Medical Home Initiative $665,000.00 Fund The Cleveland Clinic A Celebration of Survivorship $5,000.00 Foundation-BMT An Educational Symposium for Cleveland Clinic BM Sponsorship The Council of State Bowhay Institute for $5,000.00 Government, Ltd. Legislative Leadership Development The Diabetes Coalition Giving Diabetes the Blues $2,500.00 of Mississippi/ Mississippi Rural Health Association The FH Foundation CASCADE FH Registry $500,000.00 The Flood Sisters 7th Annual Love.Give.Life. $2,000.00 Kidney Foundation of Fashion Show/Gala America The Friends of Matheny Matheny Center of Medicine and $5,000.00 Dentistry The Life Raft Group Research Team Meeting $5,000.00 The Salvation Army Healthy Food Pantry Program $5,000.00 The University of First Annual Immuno-Oncology in $25,000.00 Texas Foundation, Myeloma 2015 Workshop Inc. Trustees of Boston Boston University's 15th Annual $1,500.00 University CMD Symposium on Molecular Discovery Trustees of the Research Training in $20,000.00 University of Pharmacoepidemiology Pennsylvania Tufts Medical Center CEVR Database Subscription $35,000.00 TULANE CANCER CENTER NOLA Bluedoo Party/Walk/Run $1,000.00 Tuskegee Human And Donation for Public Education $5,000.00 Civil Rights Multicultural Center UCSF Cancer Center (c/ 2015 HDFCCC Symposium: $5,000.00 o UCSF Foundation) Breakthroughs in Cancer Immunotherapy United Network for Transplant Living Program $25,000.00 Organ Sharing United States Soccer Soccer for Success--Paterson, $10,000.00 Federation Foundation NJ Inc. United Way of Greater Merial--Duluth 2014 United Way $23,984.25 Atlanta Campaign United Way of Hall 2014 United Way Campaign Match-- $2,841.50 County Inc. Merial Select United Way of SP 2014 United Way Campaign $7,221.00 Lackawanna and Wayne Payout Counties United Way of Sanofi Pasteur 2014 United Way $521.00 Massachusetts Bay Campaign Payout Inc. United Way of Monroe SP 2014 United Way Campaign $56,881.53 County Match United Way of 2014 United Way Campaign-- $5,000.00 Northeast Georgia Merial Athens United Way of Northern Caregivers Coalition $100,000.00 New Jersey Unitio Inc. T1D Education Event Series $45,000.00 Univeristy of Arizona Alternative Muscle Club $2,700.00 Foundation for the meeting benefit of Univeristy of Arizona University of Arizona Support for the Undergraduate $3,000.00 Foundation Biology Research Program Conference University of Arizona Applied Biosciences GIDP Merit $5,000.00 Foundation Scholarship University of Arizona Keep Engaging Youth in Science $6,400.00 Foundation (KEYS) High School Summer Internships University of UCSF Diabetes Center 15th $5,000.00 California, San Anniversary Symposium Francsico Foundation University of Florida New Developments in Clinical $1,000.00 Foundation, Inc. Pharmacy and Clinical Pharmacology UNIVERSITY OF MARYLAND M-Cersi Conference on Patient $10,000.00 BALTIMORE FOUNDATION Focused Drug Development INC. University of North Pharmacoepidemiology Program $20,000.00 Carolina at Chapel Donation Hill University of Southern USC/UCLA/UCSF Tri-Institutional $3,000.00 California Retreat University of Southern National Unity 2015 Conference: $5,000.00 Mississippi Community Health Workers Foundation US China Health Summit 5th US-China Health Summit at $70,000.00 Inc. Harvard University Us TOO International Us TOO 25th Anniversary $10,000.00 Educational Symposium & Gala Celebration Vision y Compromiso 13th Annual Promotoras and $10,000.00 Community Health Workers Conference Washington Legal 2015 General Operating Support $25,000.00 Foundation Washington Policy WPC's 2015 Annual Dinner $3,500.00 Center Wellness Community of School-Based Support Groups $15,000.00 Central New Jersey Winter Urologic Forum Winter Urologic Forum (WUF) $15,000.00 (WUF) Symposia Timeslot WomenHeart: The WomenHeart Science & Leadership $50,000.00 National Coalition Symposium for Women with Heart Disease WomenHeart: The National Science & Policy $25,000.00 National Coalition Summit on Women's Heart Health for Women with Heart Disease Women's Venture Fund Highest Leaf Awards $15,000.00 YMCA of Greater Boston YMCA's Diabetes Prevention $5,000.00 Program ZERO--The End of ZERO Prostate Cancer Run/Walk $1,500.00 Prostate Cancer Delaware ------------------------------------------------------------------------ Payments made by Sanofi US (2016) ------------------------------------------------------------------------ Legal Name Payment Amount Project Title ------------------------------------------------------------------------ AMERICAN DIABETES $48,070 American Diabetes Association ASSOCIATION EXPOS EXPO ------------------------------------------------------------------------ American Society of $35,000 AMERICAN ASSOCIATION FOR CANCER Transplant Surgeons RESEARCH--Networking Hub ------------------------------------------------------------------------ American Society of $35,000 American Society of Transplant Transplant Surgeons Surgeons--Bronze Level Support ------------------------------------------------------------------------ Taking Control of Your $200,000 Taking Control of Your Diabetes Diabetes--Gold Sponsorship ------------------------------------------------------------------------ Children with Diabetes $35,000 2016 Children with Diabetes (CWD) Sponsorship ------------------------------------------------------------------------ MedStar Washington $3,000 MedStar Washington Hospital Medical Center Center--Current Issues in the Care of Dialysis and Transplant Patient ------------------------------------------------------------------------ Joslin Diabetes $25,000 A Taste of Ginger Center, Inc. ------------------------------------------------------------------------ Massachusetts General $5,000 Collaborative Novel-Novel Hospital Combination Therapies Workshop ------------------------------------------------------------------------ Greater New England $7,000 Economic Development Minority Supplier ------------------------------------------------------------------------ Healthy Capital $2,500 Diabetes Community Resource District Initative Guide ------------------------------------------------------------------------ American Diabetes $2,500 Get Moving Challenge Association ------------------------------------------------------------------------ American Diabetes $2,500 Tour de Cure Association ------------------------------------------------------------------------ American Diabetes $2,500 2016 Step Out: Walk to Stop Association Diabetes ------------------------------------------------------------------------ AMERICAN DIABETES $2,500 Father of the Year Awards Gala ASSOCIATION INC. ------------------------------------------------------------------------ Buffalo American $2,500 2016 Buffalo Niagara Tour de Diabetes Association Cure ------------------------------------------------------------------------ CNY American Diabetes $2,500 2016 Tour de Cure Association ------------------------------------------------------------------------ Albany American $2,500 Saratoga Springs Tour de Cure Diabetes Association ------------------------------------------------------------------------ American Diabetes $2,500 Tour de Cure Michigan Association ------------------------------------------------------------------------ American Diabetes $2,000 2016 Finger Lakes Tour de Cure Association Inc. ------------------------------------------------------------------------ American Diabetes $10,000 2016 High Risk Community Association Initiatives for Southwest Florida ------------------------------------------------------------------------ American Diabetes $2,500 Charlotte Step Out: Walk to Association Stop Diabetes ------------------------------------------------------------------------ American Diabetes $2,500 Tour de Cure Hawaii Association ------------------------------------------------------------------------ American Diabetes $2,500 Step Out: Walk to Stop Diabetes Association Upstate, SC ------------------------------------------------------------------------ American Diabetes $2,500 American Diabetes Association's Association Boston Step Out Walk to STOP Diabetes ------------------------------------------------------------------------ American Diabetes $2,500 American Diabetes Association's Association Connecticut Step Out Walk to STOP Diabetes ------------------------------------------------------------------------ American Diabetes $2,500 American Diabetes Association's Association Central Massachusetts Step Out Walk to STOP Diabetes ------------------------------------------------------------------------ American Diabetes $2,500 2016 New Orleans Father of the Association Year ------------------------------------------------------------------------ American Diabetes $2,500 2016 Indiana Tour de Cure Association, Indiana ------------------------------------------------------------------------ AMERICAN DIABETES $75,000 Diabetes Hospitality Days: Stop ASSOCIATION INC Diabetes in New Orleans ------------------------------------------------------------------------ National Kidney $25,000 NKF Patient Programs 2016 Foundation, Inc. ------------------------------------------------------------------------ Asthma and Allergy $100,000 AAFA Patient Education and Foundation of America Outreach ------------------------------------------------------------------------ Asthma and Allergy $10,000 KFA Strides for Safe Kids Mall Foundation of America Walk and Expo ------------------------------------------------------------------------ Asthma and Allergy $15,000 KFA Patient Education and Foundation of America Outreach ------------------------------------------------------------------------ Northeast Business $20,000 eValue8--Health Plan Group on Health Performance Review ------------------------------------------------------------------------ Food Allergy Research $100,000 FOOD ALLERGY 101 Online Education Training Component and School Action Campaign Grassroots Advocacy ------------------------------------------------------------------------ American Heart $2,000 Peoria Heart and Stroke Ball Association | and Peoria and Bloomington American Stroke Heart Walk Association ------------------------------------------------------------------------ American Heart $15,000 2016 Heart Innovation Forum Association ------------------------------------------------------------------------ American Heart $2,000 Springfield Heart Ball Association | American Stroke Association ------------------------------------------------------------------------ ATS Foundation Inc $25,000 Eighth Annual ATS Foundation Research Program Benefit ------------------------------------------------------------------------ BHCAG FOUNDATION $2,500 Employer Leadership Summit ------------------------------------------------------------------------ National Alliance of $5,000 11th Annual Meeting State Prostate Cancer Coalitions ------------------------------------------------------------------------ New York Stem Cell $2,000 The NYSCF Conference Foundation, Inc. ------------------------------------------------------------------------ Opportunity Through $1,000 Arizona Pavilion at BIO 2016 Entrepreneurship Foundation ------------------------------------------------------------------------ Somerset Health Care $1,000 Healthier Somerset Foundation ------------------------------------------------------------------------ Diabetes Foundation $10,000 25th Anniversary Awards Dinner Inc. & Talent Competition ------------------------------------------------------------------------ JDRF $2,500 One Walk Philadelphia ------------------------------------------------------------------------ JDRF $2,500 JDRF One Promise Gala Allentown--Passport to a Cure ------------------------------------------------------------------------ JDRF $2,500 Rockin' Docs for Diabetes Cure ------------------------------------------------------------------------ JDRF $2,500 2016 JDRF Poconos One Walk ------------------------------------------------------------------------ JDRF $12,000 JDRF One Promise Gala Philadelphia ------------------------------------------------------------------------ JDRF $2,500 2016 JDRF Moosic One Walk ------------------------------------------------------------------------ JDRF $2,500 2016 JDRF Reading One Walk ------------------------------------------------------------------------ JDRF $2,500 One Walk Newtown ------------------------------------------------------------------------ JDRF $2,500 2016 JDRF Lehigh Valley One Walk ------------------------------------------------------------------------ JDRF $2,500 ACE For A Cure ------------------------------------------------------------------------ JDRF Central PA $2,500 JDRF One Walk--Lancaster Chapter ------------------------------------------------------------------------ JDRF New York City $15,000 44th Annual Promise Ball Chapter ------------------------------------------------------------------------ JDRF International $2,500 34th Annual Boston Gala ------------------------------------------------------------------------ JDRF INTERNATIONAL $50,000 2016 TypeOneNation Summits ------------------------------------------------------------------------ JDRF INTERNATIONAL $50,000 2016 JDRF Government Day ------------------------------------------------------------------------ JDRF Greater Dallas $2,500 JDRF One Walk, Dallas ------------------------------------------------------------------------ Juvenile Diabetes $2,500 Rock the Cure Research Foundation ------------------------------------------------------------------------ JDRF $10,000 JDRF Imagine Gala ------------------------------------------------------------------------ National Comprehensive $10,000 Emerging Issues in Oncology--An Cancer Network NCCN Roundtable Discussion ------------------------------------------------------------------------ American Society for $2,500 ASN Annual Meeting Neurochemistry ------------------------------------------------------------------------ American Orthopaedic $50,000 Early Osteoarthritis/Prevention Society for Sports of Disease Progression Medicine ------------------------------------------------------------------------ Diabetes Foundation of $2,000 LIVE-A-BETES: Learning To Live Mississippi Well With Diabetes ------------------------------------------------------------------------ Renal Physicians $10,000 RPA Kidney Quality Improvement Association Registry ------------------------------------------------------------------------ New York & New Jersey $8,000 Annual Sponsorship Minority Supplier Development Council ------------------------------------------------------------------------ Gordon Research $3,000 2016 Gordon Research Conference Conference (GRC) entitled Autophagy in Stress, Development, and Disease: From the basics to therapeutic targets ------------------------------------------------------------------------ Gordon Research $2,000 Drug Carriers in Medicine and Conference Biology ------------------------------------------------------------------------ Gordon Research $10,000 Gordon Research Conference Conference Antibody Biology & Engineering March 2016 ------------------------------------------------------------------------ PATIENT EMPOWERMENT $20,000 2016 Town Meeting for Advanced NETWORK Prostate Cancer Patients ------------------------------------------------------------------------ PATIENT EMPOWERMENT $25,000 Online Advanced Prostate News NETWORK Coverage for Patients ------------------------------------------------------------------------ Bioscience Association $1,500 WV Bioscience Summit 2016 of WV ------------------------------------------------------------------------ Arthritis Foundation $2,000 Sponsorship for Arthritis Foundation Crystal Ball ------------------------------------------------------------------------ National Transitions $125,000 NTOCC of Care Coalition ------------------------------------------------------------------------ American Medical $50,000 AMSSM Foundation Research Grant Society for Sports Awards Medicine Foundation, Inc. ------------------------------------------------------------------------ Biocom $10,000 Global Life Science Partnering Conference ------------------------------------------------------------------------ Biocom $10,000 Global Life Science Partnering Conference ------------------------------------------------------------------------ Taking Control of Your $200,000 Taking Control Of Your Diabetes Diabetes Conferences and Health Fairs ------------------------------------------------------------------------ Prescription Drug $1,000 Legislative Reception and Assistance Foundation Celebration of Access ------------------------------------------------------------------------ The Cleveland Clinic $95,275 Advances in Organ Foundation Transplantation--Annual Fellows Conference ------------------------------------------------------------------------ Employers Health $6,500 Employer Health 2016 Annual Coalition, Inc. Symposium ------------------------------------------------------------------------ Respiratory Health $750 Lung Health Education Association ------------------------------------------------------------------------ Us TOO International $15,000 Prostate Cancer News You Can Use ------------------------------------------------------------------------ Us TOO International $5,000 Prostate Cancer Educational Webinar ------------------------------------------------------------------------ Us TOO International $5,000 Us TOO Prostate Cancer Business Leadership Council ------------------------------------------------------------------------ Blood and Marrow $25,000 Celebrating a Second Chance at Transplant Life 2016 Survivorship Information Network Symposium ------------------------------------------------------------------------ Blood and Marrow $7,500 2016 BMT InfoNet Transplant Transplant Webinar Series Information Network ------------------------------------------------------------------------ PCMA $80,000 2016 sPCMA Business Forum ------------------------------------------------------------------------ PCMA $95,000 2016 Annual Meeting Presidential Sponsorship ------------------------------------------------------------------------ Regents of the $40,000 V-BID Summit 2016 University of Michigan ------------------------------------------------------------------------ Minnesota Society of $6,000 MSHP 2016 Corporate Business Health-System Partnership Program Pharmacists ------------------------------------------------------------------------ Be The Match $25,000 National Sponsorship for Be The Foundation Match Walk+Run ------------------------------------------------------------------------ Mid-America Coalition $5,000 4th Annual Workforce & on Health Care Community Well-Being Forum ------------------------------------------------------------------------ Global Virus Network, $10,000 8th International Global Virus Inc. Network Meeting ------------------------------------------------------------------------ CrowdCare Foundation, $10,000 Muscles for Myeloma Inc. ------------------------------------------------------------------------ PRIDE $6,000 PRIDE Conference ------------------------------------------------------------------------ The diaTribe $100,000 d16 Executive Forum Foundation ------------------------------------------------------------------------ US China Health Summit $70,000 5th US-China Health Summit at Inc. Harvard University ------------------------------------------------------------------------ Greater Philadelphia $5,000 GPBCH 2016 Annual Conference Business Coalition on Health ------------------------------------------------------------------------ Food Allergy & $100,000 FAACT Education Programs Anaphylaxis Connection Team ------------------------------------------------------------------------ Deep South Cancer $5,000 2016 Cycliad Charity Bicycle Foundation Ride ------------------------------------------------------------------------ California Life $2,500 CLSA Life Sciences Academy Sciences Association ------------------------------------------------------------------------ Globalization of $3,500 GPEN2016 Pharmaceutics Education Network, Inc. ------------------------------------------------------------------------ American Association $20,000 Public Policy Forum 2016 of Diabetes Educators ------------------------------------------------------------------------ Federation of American $5,000 FASEB conference on Muscle Societies for Satellite Cells and Experimental Biology Regeneration (FASEB) ------------------------------------------------------------------------ Teratology Society $1,500 Teratology Society 56th Annual Meeting ------------------------------------------------------------------------ Biotechnology $145,000 BIO International Convention Innovation Organization ------------------------------------------------------------------------ Biotechnology $40,000 BIO Europe Spring and BIO Innovation Europe International Organization Partnering Conference ------------------------------------------------------------------------ Maryland Black Caucus $2,000 Maryland Black Caucus Foundation, Inc. Foundation, Inc. ------------------------------------------------------------------------ American Cancer $25,083 2016 ACS CAN Fundraising Events Society Cancer Action and ACS CAN advocacy Network activities ------------------------------------------------------------------------ Mid Atlantic Lifespan, $4,000 Senior Care Providers Inc. Roundtables With Local Hospitals ------------------------------------------------------------------------ ACS Organic Chemistry $1,500 ACS-DOC Graduate Research Division Symposium ------------------------------------------------------------------------ Society of Toxicology $10,000 Society of Toxicology Annual Meeting ------------------------------------------------------------------------ NATIONAL ACADEMY OF $50,000 Forum on Neuroscience and SCIENCES Nervous System Disorders ------------------------------------------------------------------------ NATIONAL ACADEMY OF $85,000 Forum on Drug Discovery, SCIENCES Development and Translation ------------------------------------------------------------------------ Allergy & Asthma $100,000 AAP Asthma, Allergy & Network Mothers of Anaphylaxis Champion Program Asthmatics ------------------------------------------------------------------------ Virginia Bio $1,500 Legislative Reception ------------------------------------------------------------------------ AMGA Foundation Inc $200,000 Together 2 Goal ------------------------------------------------------------------------ International Society $70,000 World Kidney Day 2016 of Nephrology ------------------------------------------------------------------------ Florida Health Care $7,500 ``The Health Care Revolution: Coalition Building the Health Rosetta'' ------------------------------------------------------------------------ Florida Caucus of $2,000 Scholarship Black State Legislators ------------------------------------------------------------------------ Fundacion Centro $15,000 Diabetes Summer Camp 2016 Pediatrico de Diabetes ------------------------------------------------------------------------ American Drug $15,000 American Drug Utilization Utilization Review Review Symposium Society ------------------------------------------------------------------------ The University of $25,000 Second Annual Immuno-Oncology Texas Foundation, and Myeloma Workshop Inc. ------------------------------------------------------------------------ El Paso Diabetes $2,500 2016 Diabetes Walk/Run Association, Inc. ------------------------------------------------------------------------ National TB $2,500 Using the Stories and Voices of Controllers TB Survivors for Patient Association Education, Building a Supportive Community, and Advocacy ------------------------------------------------------------------------ French American $1,000 FACS XVI Chemical Society ------------------------------------------------------------------------ Texas Tech Foundation, $286,000 Community Health Worker (CHW) Inc. Core Consensus Project 2016: Increasing Stakeholder Engagement and Endorsement, Defining CHW Roles and Skills in Clinical and Community Settings, and CHW Skill Assessment Approaches and Tools ------------------------------------------------------------------------ Houston Business $6,000 The Employer's Specialty Coalition on Health Pharmaceutical Dilemma-- Challenges & Opportunities ------------------------------------------------------------------------ UNM Comprehensive $1,000 Hoops4Hope Cancer Center ------------------------------------------------------------------------ University of Utah $50,000 Western Atrial Fibrillation Symposium ------------------------------------------------------------------------ WithinReach $5,000 Improving Health Access and Immunization Policy ------------------------------------------------------------------------ NASPA $5,000 NASPA Leadership Conference Awareness Walk ------------------------------------------------------------------------ National Eczema $300,000 Roadmap to Advocacy Association ------------------------------------------------------------------------ American Society on $5,000 2016 Aging in America Aging Conference ------------------------------------------------------------------------ Milken Institute $500,000 2016 Milken Institute Conference Engagement ------------------------------------------------------------------------ International Myeloma $100,000 IMF Patient Programs 2016 Foundation ------------------------------------------------------------------------ International Myeloma $5,000 IMF 10th Annual Comedy Foundation Celebration benefitting the Peter Boyle Research Foundation ------------------------------------------------------------------------ International Myeloma $35,000 7th Annual Internaltional Foundation Myeloma Working Group Summit ------------------------------------------------------------------------ California Center for $2,500 Pre-diabetes Epidemic in Public Health California--What Now? Advocacy ------------------------------------------------------------------------ Out & Equal $25,000 2016 Out & Equal Workplace Summit ------------------------------------------------------------------------ GLBTQ Legal Advocates $3,000 GLAD 2016 Summer Party & Defenders ------------------------------------------------------------------------ Gay Men's Health $5,000 AIDS Walk New York Crisis, Inc ------------------------------------------------------------------------ The Children's Aid $25,000 The Children's Aid Society 5th Society Annual KTP Gala ------------------------------------------------------------------------ Jersey Battered $7,000 JBWS Grand Tastings XXII Women's Service, Inc. ------------------------------------------------------------------------ Community Hope, Inc. $10,000 2016 Silver Corporate Partner ------------------------------------------------------------------------ RESOURCES USA INC $7,500 French Talks ------------------------------------------------------------------------ Court Appointed $1,000 Night of a Thousand Stars Gala Special Advocates of Mercer County, Inc. ------------------------------------------------------------------------ Machestic Dragons $5,000 10th Annual ``Paddle for Pink'' Community Dragon Boat Festival ------------------------------------------------------------------------ American Lebanese $10,000 St. Jude Gourmet Gala Syrian Associated Charities, Inc. ------------------------------------------------------------------------ National Kidney $1,000 Champion of Hope Tribute Dinner Foundation of Michigan ------------------------------------------------------------------------ National Congressional $25,000 Gold Membership Award Foundation ------------------------------------------------------------------------ Research!America $25,000 20th Annual Advocacy Awards Dinner ------------------------------------------------------------------------ Society for Women's $10,000 2016 SWHR Annual Gala Dinner Health Research ------------------------------------------------------------------------ American Cancer $2,500 Relay For Life of Bridgewater Society Cancer Action Network ------------------------------------------------------------------------ University of Arizona $3,000 Sponsorship of the 28th Annual Foundation Undergraduate Biology Research Program Conference ------------------------------------------------------------------------ Diabetes Hands $37,500 Online Community for People Foundation with Diabetes ------------------------------------------------------------------------ Boston University $2,500 Boston University School of School of Public Public Health 40th Anniversary Health Gala ------------------------------------------------------------------------ Pro Bono Partnership $10,000 Pro Bono Partnership 2016 Gala ------------------------------------------------------------------------ Christ The King $5,000 8th Annual President's Gala Preparatory School of Newark NJ Corp. ------------------------------------------------------------------------ Children's Health Fund $25,000 2016 Annual Benefit ------------------------------------------------------------------------ The Children's Aid $25,000 The Children's Aid Society's Society Keeping the Promise Benefit ------------------------------------------------------------------------ The American Heart $5,000 Heart & Stroke Ball Association ------------------------------------------------------------------------ Good Grief Inc. $2,500 2016 Great Pumpkin Ball ------------------------------------------------------------------------ United Way of Northern $500 Pathways for Caregivers 2016 New Jersey Reprint ------------------------------------------------------------------------ Easterseals New Jersey $1,350 46th Annual Raritan Valley Workshop Dinner Dance ------------------------------------------------------------------------ Safe+Sound Somerset $10,000 Soaring to New Heights ------------------------------------------------------------------------ Deirdre O'Brien Child $2,000 Gala Sponsorship Advocacy Center Inc. ------------------------------------------------------------------------ The Center For Great $5,000 2016 Gift of Hope Gala Expectations Inc ------------------------------------------------------------------------ Somerset County $500 Second Annual Workplace Health Business Partnership & Wellness Expo 2016 ------------------------------------------------------------------------ RESOURCES USA INC. $5,000 Bastille Day 2016 ------------------------------------------------------------------------ RESOURCES USA INC $5,000 Bastille Day events ------------------------------------------------------------------------ CANCER SUPPORT $5,000 Inspiring Hope COMMUNITY CENTRAL NEW JERSEY ------------------------------------------------------------------------ Auxiliary of the $5,000 57th Annual Auxiliary Autumn Robert Wood Johnson Ball University Hospital ------------------------------------------------------------------------ Pocono Mountains $6,000 Pocono Mountains Community Community Challenge Fundraiser Fund ------------------------------------------------------------------------ The American Kidney $50,000 2016 The Hope Affair Fund, Inc. ------------------------------------------------------------------------ Partnership for a $4,500 PHA Fit to Celebrate Gala Healthier America Inc. ------------------------------------------------------------------------ American Society of $75,000 2017 Corporate Sponsor Transplant Surgeons Foundation ------------------------------------------------------------------------ Vision y Compromiso $5,000 Hacia Una Vida y Sana, the 13th Annual Promotoras and Community Health Workers Conference ------------------------------------------------------------------------ Turn 2 Foundation Inc. $15,000 Turn 2 Foundation 20th Annual Dinner ------------------------------------------------------------------------ AAALAC International $5,000 IQ/AAALAC International Global 3Rs Award Program ------------------------------------------------------------------------ Asthma & Allergy $1,000 Fall 2016 AAFA-STL Printed Foundation of Newsletter America, St. Louis Chapter ------------------------------------------------------------------------ Autoimmune Advocacy $2,500 A Grapevine Grows Alliance ------------------------------------------------------------------------ Operation Warrior $7,500 Warrior Wishes 2016 Army/Navy Wishes Foundation Game ------------------------------------------------------------------------ Washington Legal $30,000 2016 General Operating Support Foundation ------------------------------------------------------------------------ Maryland Black Caucus $2,500 Legislative Weekend Foundation, Inc. ------------------------------------------------------------------------ Research!America $10,000 National Health Research Forum ------------------------------------------------------------------------ Friends of Cancer $25,000 Friends of Cancer Research 20th Research Anniversary Cancer Leadership Awards Dinner ------------------------------------------------------------------------ Project Hope The $10,000 2016 Project HOPE Gala People To People Health Foundation Inc. ------------------------------------------------------------------------ The Virginia Public $700 Lighten Up, It's Just Politics Access Project ------------------------------------------------------------------------ AMGA Foundation Inc. $10,000 AMGA Foundation 50th Anniversary Gala ------------------------------------------------------------------------ CEO Roundtable on $500,000 Project Data Sphere initiative Cancer ------------------------------------------------------------------------ Conference of Western $5,000 CWAG 2016 Winter Dinner Attorneys General Sponsorship ------------------------------------------------------------------------ Western Governors' $10,000 WGA Annual Contribution Foundation ------------------------------------------------------------------------ Colon Cancer Alliance $3,500 2016 Blue Hope Bash ------------------------------------------------------------------------ American Statistical $9,500 Breiamn Award Association ------------------------------------------------------------------------ Washington Policy $4,000 2016 Annual Dinner Center ------------------------------------------------------------------------ NEHI (Network for $75,000 Health Care Without Walls Excellence in Health Innovation) ------------------------------------------------------------------------ Cheshire Health $1,000 Cheshire Stepping Out for Foundation Diabetes Walk ------------------------------------------------------------------------ Massachusetts General $5,000 The Role of Tumor Hospital Microenvironment: a 40-year Journey ------------------------------------------------------------------------ Massachusetts General $5,000 Massachusetts General Hospital Hospital Immunology Seminar Series ------------------------------------------------------------------------ YMCA of Greater Boston $10,000 YMCA's Diabetes Prevention Program ------------------------------------------------------------------------ MIT 100K $25,000 MIT 100K Entrepreneurship Entrepreneurship Competition Competition ------------------------------------------------------------------------ Joslin Diabetes $10,000 High Hopes Gala Center, Inc. ------------------------------------------------------------------------ Joslin Diabetes $2,500 Ritmos de salud (healthy Center, Inc. rhythms) ------------------------------------------------------------------------ Multi Regional $50,000 Multi Regional Clinical Trials Clinical Trials Center of Brigham and Women's Center of Brigham and Hospital and Harvard Women's Hospital and Harvard ------------------------------------------------------------------------ Foundation for $12,500 Animal Research Communications Biomedical Research Campaign ------------------------------------------------------------------------ Foundation for $20,000 Public Education to Advance Biomedical Research Understanding of Animal Research ------------------------------------------------------------------------ Massachusetts Society $2,500 The MSMR Annual Meeting of for Medical Research, Members Inc. ------------------------------------------------------------------------ Children's Hospital $10,000 PCMM Retreat Corporation ------------------------------------------------------------------------ Foundation for $5,000 Scientific Symposium in honor Neurologic Diseases, Vijay K. Kuchroo Inc. ------------------------------------------------------------------------ Lake Norman Community $1,000 Sunset and Sandals Health Clinic ------------------------------------------------------------------------ Multiple Myeloma $50,000 Multiple Myeloma Educational Research Foundation Programming ------------------------------------------------------------------------ American Diabetes $2,500 CNY Diabetes Community Forum Association Inc. ------------------------------------------------------------------------ American Diabetes $5,000 Community Awareness Training Association ------------------------------------------------------------------------ American Diabetes $2,500 Step Out Walk to Stop Diabetes-- Association Phoenix ------------------------------------------------------------------------ American Diabetes $2,500 2016 Kiss a Pig Gala Association ------------------------------------------------------------------------ American Diabetes $2,500 American Diabetes Association's Association Connecticut Tour de Cure ------------------------------------------------------------------------ American Diabetes $5,000 American Diabetes Association Association New England Classic Multi-Day Tour de Cure ------------------------------------------------------------------------ American Diabetes $2,500 American Diabetes Association's Association Kennebunks Tour de Cure ------------------------------------------------------------------------ American Diabetes $2,500 American Diabetes Association's Association Ocean State Tour de Cure ------------------------------------------------------------------------ American Diabetes $2,500 American Diabetes Association's Association North Shore Tour de Cure ------------------------------------------------------------------------ American Diabetes $10,000 ADA Indiana's Josiah Kirby Association, Indiana Lilly Sr. Distinguished Service Award Gala ------------------------------------------------------------------------ American Diabetes $2,500 2016 Father of the Year Awards Association Dinner ------------------------------------------------------------------------ American Diabetes $50,000 Diabetes Awareness and Association Intervention--via Step Out: Walk to Stop Diabetes, the Red Rider/Red Strider Program and the Annual Diabetes Conference in NJ ------------------------------------------------------------------------ American Diabetes $2,500 2016 World Diabetes Day Summit Association ------------------------------------------------------------------------ American Diabetes $20,000 Unmasking Diabetes Gala & Association Awards ------------------------------------------------------------------------ American Diabetes $2,500 Step Out Walk to Stop Diabetes Association of the Triangle ------------------------------------------------------------------------ American Diabetes $2,500 Tour De Cure + Step Out: Walk Association to Stop Diabetes ------------------------------------------------------------------------ American Diabetes $2,500 Father of the Year Awards Association ------------------------------------------------------------------------ National Health $100,000 The Patient Perspective on the Council Value of Treatments ------------------------------------------------------------------------ National Health $95,000 Health Technology Assessments Council and Value: The Patient Perspective ------------------------------------------------------------------------ National Kidney $50,000 2016 New York City Kidney Walk Foundation, Inc. and Patient Journeys ------------------------------------------------------------------------ National Kidney $15,000 2016 Boston Kidney Walk Foundation ------------------------------------------------------------------------ Organization for $15,000 2016 OFII Annual Dinner International Investment ------------------------------------------------------------------------ Healthcare $8,850 HBA Woman of the Year Elite Businesswomen's Table Association ------------------------------------------------------------------------ United States Bone and $20,000 Burden of Musculoskeletal Joint Initiative, NFP Diseases in the United States (BMUS) Report ------------------------------------------------------------------------ United States Bone and $80,000 Experts in Arthritis (EIA) Joint Initiative, NFP ------------------------------------------------------------------------ American College of $150,000 LDL Address the Risk Think Tank Cardiology ------------------------------------------------------------------------ The Leukemia & $2,500 Lowcountry Light The Night Walk Lymphoma Society ------------------------------------------------------------------------ The Leukemia & $16,000 Light The Night Sponsorship Lymphoma Society ------------------------------------------------------------------------ THE LEUKEMIA & $50,000 Band Against Cancer: The Sarah LYMPHOMA SOCIETY Cannon Tour ------------------------------------------------------------------------ Moses E. Cheeks Slam $2,500 Moses E. Cheeks Slam Dunk for Dunk for Diabetes Diabetes Basketball Camp ------------------------------------------------------------------------ American Foundation $25,000 2016 Get in Rhythm. Stay in for Women's Health Rhythm. Atrial Fibrillation (dbaStopAfib.org) Patient Conference ------------------------------------------------------------------------ National Alliance of $5,000 Advanced Prostate Cancer State Prostate Cancer Laminate Coalitions ------------------------------------------------------------------------ National Alliance of $5,000 12th Annual Meeting of the State Prostate Cancer National Alliance of State Coalitions Prostate Cancer Coalitions ------------------------------------------------------------------------ Colorectal Cancer $10,000 Guide in the Fight for Late Coalition Inc Stage CRC Patients ------------------------------------------------------------------------ Myotonic Dystrophy $3,000 MDF Annual Conference Foundation ------------------------------------------------------------------------ New Jersey Association $1,000 3Rs Sharing Conference V for Biomedical Research, Inc. ------------------------------------------------------------------------ Academy of Managed $15,000 AMCP 2016 Partnership Forum: Care Pharmacy Enabling the Exchange of Clinical and Economic Data Pre- FDA Approval ------------------------------------------------------------------------ Academy of Managed $18,000 AMCP Oncology Management Care Pharmacy Partnership Forum ------------------------------------------------------------------------ BIONJ INC. $10,000 Annual Dinner ------------------------------------------------------------------------ Community Oncology $15,000 Oncology Care Model Filming Alliance ------------------------------------------------------------------------ Community Oncology $7,500 Community Oncology Alliance CMS Alliance Oncology Care Model Payer Session ------------------------------------------------------------------------ Community Oncology $25,000 2016 Community Oncology Payer Alliance Exchange Summit V Oncology Payment Reform ------------------------------------------------------------------------ JDRF International $2,500 JDRF One Walk 2016 ------------------------------------------------------------------------ JDRF $5,000 JDRF One Walk Pittsburgh ------------------------------------------------------------------------ JDRF $5,000 JDRF One Walk Westmoreland ------------------------------------------------------------------------ Juvenile Diabetes $2,500 JDRF One Walk Rochester Research Foundation ------------------------------------------------------------------------ Juvenile Diabetes $2,500 JDRF One Walk Southern Tier Research Foundation ------------------------------------------------------------------------ JDRF NENY $2,500 JDRF Saratoga One Walk ------------------------------------------------------------------------ JDRF--Western New York $2,500 JDRF Buffalo One Walk Chapter ------------------------------------------------------------------------ JDRF International $2,500 JDRF One Walk Boston 2016 ------------------------------------------------------------------------ American Society of $10,000 Mambo for Myeloma ASH Hematology Sponsorship ------------------------------------------------------------------------ The American Kidney $5,000 2016 A Pairing For Prevention Fund, Inc. ------------------------------------------------------------------------ The American Kidney $75,000 New To Dialysis Campaign Fund, Inc. ------------------------------------------------------------------------ THE TRANSPLANTATION $50,000 TTS Transplantation Leadership SOCIETY Series ------------------------------------------------------------------------ PROMIS Health $10,000 PROMIS: Measuring Health Organization (PHO) Outcomes Around the World ------------------------------------------------------------------------ The Foundation for $5,000 International Research Peripheral Neuropathy Symposium/Advances in Neuropathy--Emerging Therapies ------------------------------------------------------------------------ PQA, Inc. $5,000 PQA Leadership Summit 2016 ------------------------------------------------------------------------ PQA, Inc. $25,000 PQA Insulin Adherence Committee ------------------------------------------------------------------------ MMORE: Multiple $5,000 MoveMMORE Seattle 2016 Myeloma Opportunities for Research & Education ------------------------------------------------------------------------ International Society $5,000 ACoP7 meeting of Pharmacometrics ------------------------------------------------------------------------ The Galien Foundation $15,000 The Galien Forum ------------------------------------------------------------------------ MassChallenge, Inc. $4,000 2016 MC Awards ------------------------------------------------------------------------ MassChallenge, Inc. $40,000 MassChallenge ------------------------------------------------------------------------ Alliance for $5,000 Cell & Gene Meeting on the Mesa Regenerative Medicine ------------------------------------------------------------------------ Oklahoma Center for $3,000 Transformation of Healthcare: Healthcare CPC Learning Session Improvement ------------------------------------------------------------------------ Health Literacy $225,000 The Blue Ribbon Online Missouri Clearinghouse of Kidney Transplantation and Living Donation Resources (BROC) ------------------------------------------------------------------------ Health Literacy $50,000 My Transplant Coach Application Missouri Development Project ------------------------------------------------------------------------ Center for Medical $40,000 GPC--Real World Evidence Technology Policy ------------------------------------------------------------------------ Center for Healthcare $7,500 2016 Diversity, Inclusion, & Innovation Life Sciences Symposium ------------------------------------------------------------------------ BIO Ventures for $10,000 2016 BIO International Global Health (BVGH) Convention Africa Pavilion ------------------------------------------------------------------------ National Transitions $50,000 NTOCC Mission Support of Care Coalition ------------------------------------------------------------------------ The American College $6,000 2016 ACVP/ASVCP Concurrent of Veterinary Annual Meeting Pathologists ------------------------------------------------------------------------ South Dakota Diabetes $1,000 Third Annual Sweet Success Coalition Extravaganza ------------------------------------------------------------------------ T. Leroy Jefferson $2,000 2016 Community Health Fair: Medical Society Healthy Children for a Healthy Future ------------------------------------------------------------------------ North Coast Health $1,000 Celebration of Caring 2016 ------------------------------------------------------------------------ Academy of Nutrition $18,000 DCE On the Cutting Edge and Dietetics on newsletter behalf of Diabetes Care and Education ------------------------------------------------------------------------ America's Health $55,000 Executive Leadership Program Insurance Plans ------------------------------------------------------------------------ American Liver $2,500 Diabetes and NASH Webinar Foundation ------------------------------------------------------------------------ Us TOO International $2,500 12th Annual SEA Blue Chicago Prostate Cancer Walk & Run ------------------------------------------------------------------------ Blood and Marrow $2,500 BMT InfoNet Resource Directory Transplant update and reprint Information Network ------------------------------------------------------------------------ Chicago Hispanic $1,000 10th Annual Vive tu Vida/Get Health Coalition Up! Get Moving! Health and Wellness Fair ------------------------------------------------------------------------ The Council of State $5,000 Bowhay Institute Government, Ltd. ------------------------------------------------------------------------ National Bone Marrow $5,000 Update, Edit and Transplant Transplant Link Survivors' Guide for Bone Marrow, Stem Cell and Cord Blood Transplant ------------------------------------------------------------------------ International Society $8,000 Corporate Membership for Application Pharmacoepidemiology ------------------------------------------------------------------------ Be The Match $90,000 Quick Reference Guidelines-- Foundation Transplant Consultation and Post-Transplant Care ------------------------------------------------------------------------ American Society of $10,000 Meet the Faculty Networking Transplantation Session @ 2016 AST Fellows Symposium on Transplantation ------------------------------------------------------------------------ Iowa Pharmacy $10,000 2016 Leadership in Pharmacy Association advocacy program Foundation ------------------------------------------------------------------------ Mid-America Coalition $4,000 Type 2 Diabetes in Kansas City: on Health Care A Collaborative Approach ------------------------------------------------------------------------ St. Louis Children's $50,000 Food Allergy Management and Hospital Foundation Education (FAME) ------------------------------------------------------------------------ Missouri Biotechnology $1,000 BIO Benchmarking Program Association ------------------------------------------------------------------------ Metabolic Endocrine $25,000 14th Annual World Congress on Education Foundation Insulin Resistance Diabetes and Cardiovascular Disease (WCIRDC) ------------------------------------------------------------------------ The diaTribe $5,000 10th Annual Diabetes Forum Foundation ------------------------------------------------------------------------ Greater Philadelphia $1,000 GPBCH Annual Wellness Summit Business Coalition on Health ------------------------------------------------------------------------ Project Access of $500 Diabetic Walk Howard County ------------------------------------------------------------------------ National Diabetes $14,000 Access to Insulin Patient Volunteer Leadership Advocacy Study Council ------------------------------------------------------------------------ Keystone for $5,000 Foundation2016 Conference Incubating Innovation in Life sciences Network (KiiLN) ------------------------------------------------------------------------ ALL IN TOGETHER $25,000 All In Together Campaign Women CAMPAIGN INC in Healthcare Policy Forum ------------------------------------------------------------------------ Washington Health $6,600 2016 Alliance Membership Alliance ------------------------------------------------------------------------ IIT Association of $2,500 2016 PanIIT Leadership Greater New England Conference ------------------------------------------------------------------------ California Life $7,500 2016 Life Sciences Academy Sciences Association ------------------------------------------------------------------------ The Kansas Chamber $884 Corporate Membership ------------------------------------------------------------------------ Delaware Diabetes $2,500 Delaware Diabetes Coalition Coalition 2016 EXPO ------------------------------------------------------------------------ American Legislative $10,000 Life Sciences Academy Exchange Council ------------------------------------------------------------------------ Biotechnology $10,000 ODTC White Paper Innovation Organization ------------------------------------------------------------------------ Biotechnology $20,000 State Policy Maker Round Tables Innovation on Value of Biopharmaceutical Organization (BIO) Industry ------------------------------------------------------------------------ American Association $50,000 Sustaining Sponsorship of Pharmaceutical Scientists ------------------------------------------------------------------------ Society for Women's $10,000 National Conference on Women's Health Research Health Research--Diabetes/ Metabolism ------------------------------------------------------------------------ International $33,000 IPEC-Americas 2016 Membership Pharmaceutical Dues Excipients Council of the Americas (IPEC- Americas) ------------------------------------------------------------------------ FSH Society $2,500 FSHD Connect Conference ------------------------------------------------------------------------ International Society $10,000 RECOMB/ISCB Conference on for Computational Regulatory and Systems Biology, Inc. Genomics with DREAM Challenges ------------------------------------------------------------------------ WomenHeart: The $25,000 Access NOW! Campaign National Coalition for Women with Heart Disease ------------------------------------------------------------------------ Springboard 2000 $15,000 Health Innovation Hub Enterprises, Inc. ------------------------------------------------------------------------ American Cancer $1,000 2016 ACS CAN Michigan Forum and Society Cancer Action ACS CAN advocacy activities Network nationwide ------------------------------------------------------------------------ APhA Foundation $168,870 Consensus Consortium on Patient Self-Management Credentialing (PSMC) and Value-Based Health Benefit Design Considerations in Patient-Centered, Team- Based Care ------------------------------------------------------------------------ Society of Toxicology $2,500 The Use of Cardiomyocytes for the Assessment of Proarrhythmic Risk ------------------------------------------------------------------------ Camp Holiday Trails $2,500 Family Diabetes Camp and Summer Camperships ------------------------------------------------------------------------ Women In Government $5,000 2016 Healthcare Summit Diabetes Foundation, Inc. Programming ------------------------------------------------------------------------ Women In Government $20,000 Diabetes Campaign--Phase II Foundation, Inc. ------------------------------------------------------------------------ Patient Advocate $35,000 Understanding What Patients Foundation Value and What and Matters to Them During Their Treatment: The Prostate Cancer Research Program (PCRP) ------------------------------------------------------------------------ Organ Donation and $4,500 National Critical Issues Forum Transplantation Alliance ------------------------------------------------------------------------ Arthritis Foundation, $40,000 ICER Survey Inc. ------------------------------------------------------------------------ Georgia Life Sciences $1,500 Georgia Life Sciences Coalition Coalition ------------------------------------------------------------------------ International Cytokine $15,000 4TH ANNUAL MEETING OF THE and Interferon INTERNATIONAL CYTOKINE AND Society Inc. INTERFERON SOCIETY (ICIS) ------------------------------------------------------------------------ American Association $25,000 AACE Diabetes Resource Center, of Clinical 2016-17 Endocrinologists ------------------------------------------------------------------------ ZERO--The End of $5,000 ZERO Prostate Cancer Community Prostate Cancer Advocacy Events ------------------------------------------------------------------------ The Diabetes Coalition $2,500 Giving Diabetes the Blues of Mississippi/ Mississippi Rural Health Association ------------------------------------------------------------------------ University of Southern $5,000 National Unity 2016 Conference: Mississippi Community Health Workers - Foundation Social Change Agents Advancing Health Equity and Improving Outcomes ------------------------------------------------------------------------ NBCH $25,000 High Value Health: Making the Dream a Reality ------------------------------------------------------------------------ Fundacion Centro $5,000 World Diabetes Month Pediatrico de Celebration 2016 Diabetes ------------------------------------------------------------------------ Fundacion Centro $3,500 XV Annual Gala Dinner Pediatrico de Diabetes ------------------------------------------------------------------------ TULANE CANCER CENTER $1,000 NOLA Bluedoo Run/Walk ------------------------------------------------------------------------ NCSL Foundation for $7,500 NCSL LegisBrief Sponsorship State Legislatures ------------------------------------------------------------------------ Arizona Diabetes $2,500 Arizona Diabetes Foundation Foundation ------------------------------------------------------------------------ Federation of Clinical $10,000 FOCIS 2016 Annual Meeting Immunology Societies ------------------------------------------------------------------------ Society of Dermatology $30,000 SDPA 14th Annual Fall Physician Assistants Dermatology Conference ------------------------------------------------------------------------ Colon Cancer Alliance $10,000 2016 Live Your Best Life mCRC Patient Symposium ------------------------------------------------------------------------ National Eczema $100,000 Leaders in Eczema Forum Series Association ------------------------------------------------------------------------ Congress of California $1,500 Script Your Future Senior Seniors Education and Leader Education Research Fund ------------------------------------------------------------------------ Association of Black $20,000 Improving Access to Innovative Cardiologists Therapies in High-Risk Populations ------------------------------------------------------------------------ Lymphoma Research $3,000 Understanding Transplantation Foundation and Lymphoma Patient Guide ------------------------------------------------------------------------ Prostate Cancer $250,000 23rd Annual Scientific Retreat Foundation ------------------------------------------------------------------------ $8,708,932 Product Donations made by Sanofi US to the Sanofi Foundation for North America * (estimate) $343,602,000 ------------------------------------------------------------------------ Donations made by the Sanofi Foundation for North America ------------------------------------------------------------------------ Legal Name Payment Amount Project Title ------------------------------------------------------------------------ Trustees of Boston $125,000 National CHW Association University ------------------------------------------------------------------------ Tufts Center for the $12,500 Assessing the Use of Real World Study of Drug Evidence to Support Regulated Development Medical Research and Post- Marketing Safety Monitoring ------------------------------------------------------------------------ Cambridge Arts Council $5,000 2016 Summer Programs for Fund Magazine Beach Park ------------------------------------------------------------------------ Americares $25,000 Disaster Relief--Hurricane Matthew ------------------------------------------------------------------------ Americares $5,000 AmeriCares Airlift Benefit ------------------------------------------------------------------------ Americares $25,000 Ecuador Earthquake Response ------------------------------------------------------------------------ Americares $10,000 U.S. Disaster Assistance ------------------------------------------------------------------------ Christ The King $59,000 Corporate Work Study Program Preparatory School of Newark NJ Corp ------------------------------------------------------------------------ NAACP $10,000 Childhood Obesity ------------------------------------------------------------------------ AMERICAN DIABETES $2,500,000 Pathway to Stop Diabetes ASSOCIATION INC ------------------------------------------------------------------------ National Kidney $5,000 New Jersey Kidney Transplant Foundation, Inc. Workshop ------------------------------------------------------------------------ March of Dimes $86,000 Supporting NICU Babies and Foundation Families ------------------------------------------------------------------------ Heritage of Pride, $2,899 NYC Pride March Inc. ------------------------------------------------------------------------ Children's Health Fund $5,000 Baton Rouge--Emergency Response ------------------------------------------------------------------------ The Salvation Army $10,000 Healthy Food Pantry Program ------------------------------------------------------------------------ Columbia Univeristy $100,000 Project on Non-Communicable Mailman School of Diseases Public Health ------------------------------------------------------------------------ THE LEUKEMIA & $19,640 Fiscal Year 2017 Myeloma LYMPHOMA SOCIETY Patient Education ------------------------------------------------------------------------ Stop Hunger Now Inc. $10,000 Stop Hunger Now Disaster Ready Response ------------------------------------------------------------------------ Garden State Equality $5,000 Pledge and Protect LGBT Seniors Education Fund Inc. ------------------------------------------------------------------------ Camp Nejeda Foundation $10,000 Camp Nejeda: Helping Kids with Type 1 Diabetes Live Happier, Healthier Lives ------------------------------------------------------------------------ Matheny School and $10,000 Matheny Center of Medicine and Hospital Inc. Dentistry ------------------------------------------------------------------------ United Way of Northern $100,000 Caregivers Coalition New Jersey ------------------------------------------------------------------------ Jersey Battered $5,000 Community Counseling Services Women's Service, Inc. ------------------------------------------------------------------------ Food Bank of Somerset $10,000 Back Pack Program County Inc. ------------------------------------------------------------------------ Community Hope, Inc. $25,000 Residential Recovery Programs for Homeless Veterans and Disabled Individuals ------------------------------------------------------------------------ Hyacinth Foundation, A $15,000 Hyacinth Psychosocial Support New Jersey Non-profit Services Corporation ------------------------------------------------------------------------ Kean University $15,000 2016 Group Summer Scholars Foundation Inc Research Program ------------------------------------------------------------------------ Visiting Nurse $10,000 Hospice Care and Adult Day Club Association of Services Somerset Hills ------------------------------------------------------------------------ NJ SEEDS $10,000 Young Scholars Program--Health Sessions ------------------------------------------------------------------------ Somerset Health Care $30,000 Fun n' Fit Foundation ------------------------------------------------------------------------ Somerset Health Care $5,000 Quality CPR Saves Lives Foundation ------------------------------------------------------------------------ Somerset Health Care $10,000 El poder Foundation ------------------------------------------------------------------------ Deirdre O'Brien Child $10,000 Clinical Counseling Advocacy Center Inc ------------------------------------------------------------------------ Midland Adult Services $10,000 Midland Helping Hands Inc Employment Training Program and Midland Meals on Wheels Employment Training Program ------------------------------------------------------------------------ The Center For Great $10,000 Adult Women & their Children Expectations Inc. ------------------------------------------------------------------------ Dress For Success $10,000 Dress for Success Morris County Morris County Inc. Transforming Lives Gala ------------------------------------------------------------------------ Dress For Success $10,000 FOUNDATIONS OF SUCCESS Morris County Inc. WORKSHOPS ------------------------------------------------------------------------ The Partnership for $10,000 Community of Practice Quality Medical Donations ------------------------------------------------------------------------ Raritan Valley $3,000 College Campus Experience Day Community College for STEM High School Students Foundation ------------------------------------------------------------------------ Raritan Valley $10,000 Preparing for the Next Community College Generation Science Standards Foundation ------------------------------------------------------------------------ Raritan Valley $7,500 Galileo Scholarships: Expanding Community College Access to STEM Education Foundation ------------------------------------------------------------------------ Rutgers University $10,000 Vets4Warriors Foundation ------------------------------------------------------------------------ The American Fallen $15,000 Portrait Sponsorship Soldiers Project Inc. ------------------------------------------------------------------------ Strengthen Orlando d/b/ $5,000 OneOrlando Fund a OneOrlando Fund ------------------------------------------------------------------------ Alliance For A $25,000 America's Healthiest Schools Healthier Generation Inc. ------------------------------------------------------------------------ Diabetes Scholars $10,000 Diabetes Scholars Foundation Foundation College Scholarships ------------------------------------------------------------------------ Map International $10,000 US Disaster Relief ------------------------------------------------------------------------ Head and Neck Cancer $1,000 Research on Xerostomia in HNC Alliance patients ------------------------------------------------------------------------ United States Soccer $10,000 Soccer for Success--Camden Federation Foundation Inc. ------------------------------------------------------------------------ Camp Quality USA dba $10,000 Camp Quality NJ Camp Quality NJ ------------------------------------------------------------------------ Operation Warrior $5,000 Warrior Wishes 2016 Mission Wishes Foundation ------------------------------------------------------------------------ National Transitions $25,000 NTOCC Program Support of Care Foundation ------------------------------------------------------------------------ Sheltered Yoga $5,000 Sheltered Yoga Curriculum and Programming ------------------------------------------------------------------------ Dare to Dream Ranch $1,000 The Dare to Dream Ranch ------------------------------------------------------------------------ Provention Health $106,790 LDL Management Forum Foundation Inc. ------------------------------------------------------------------------ Heart To Heart $50,000 Hurricane Matthew Response International Inc. ------------------------------------------------------------------------ Heart To Heart $5,000 Louisiana Flood Reponse International Inc. ------------------------------------------------------------------------ Heart To Heart $10,000 U.S. Disaster Relief International Inc. ------------------------------------------------------------------------ American Society for $1,265 General Operating Support Blood and Marrow Transplantation ------------------------------------------------------------------------ Pharmaceutical $270,000 PhRMA Foundation Grants & Research and Fellowships Manufacturers of America Foundation ------------------------------------------------------------------------ Georgetown University $100,000 Health Promotion and Chronic Illness: An Educational Approach ------------------------------------------------------------------------ Patient Advocate $550,000 Metastatic Prostate & Foundation Metastatic CRC Fund ------------------------------------------------------------------------ University of North $20,000 Pharmacoepidemiology Program Carolina at Chapel Hill ------------------------------------------------------------------------ United Way of Greater $23,226 2016 Merial United Way Campaign Atlanta Sanofi Foundation Match ------------------------------------------------------------------------ United Way of Greater $24,000 Merial 2016 UW Campaign Match Atlanta ------------------------------------------------------------------------ UNITED WAY OF $5,000 Merial 2016 UW Campaign Match NORTHEAST GEORGIA INC. ------------------------------------------------------------------------ UNITED WAY OF $5,000 Merial Athens 2015 UW Campaign NORTHEAST GEORGIA INC Match ------------------------------------------------------------------------ UNITED WAY OF HALL $4,000 2016 Merial United Way Campaign COUNTY INC. Sanofi Foundation Match ------------------------------------------------------------------------ UNITED WAY OF HALL $3,615 2015 Merial United Way Campaign COUNTY INC. ------------------------------------------------------------------------ University of Arizona $5,000 Applied Biosciences Graduate Foundation for the Interdisciplinary Programs benefit of GIDP Merit Scholarship ------------------------------------------------------------------------ Direct Relief $25,000 Hurricane Matthew Response in Haiti ------------------------------------------------------------------------ Direct Relief $5,000 Louisiana Flood Response ------------------------------------------------------------------------ Cancer Support $8,000 Bringing Multiple Myeloma Community Journey Partners to the Cancer Support Community ------------------------------------------------------------------------ Partners in Research $25,000 Sanofi Biogenius Canada Canada ------------------------------------------------------------------------ Sanofi US Matching $116,524 Sanofi US Matching Gifts--Q4 Gifts--2015 (December) 2015 Match ------------------------------------------------------------------------ Tufts Medical Center $35,000 CEVR Database Subscription ------------------------------------------------------------------------ Multiple Myeloma $19,640 Mambo for Myeloma Research Foundation ------------------------------------------------------------------------ Children's Health Fund $25,000 Flint Emergency Response & Long Term Need ------------------------------------------------------------------------ Children's Health Fund $665,000 Medical Home Initiative ------------------------------------------------------------------------ Volunteers of America $5,000 Agape House Delaware Valley ------------------------------------------------------------------------ Cancer Support $15,000 School-Based Support Groups Community Central New Jersey ------------------------------------------------------------------------ Trustees of the $20,000 Research Training in University of Pharmacoepidemiology Pennsylvania ------------------------------------------------------------------------ Foundation Fighting $100,000 Supporting Research to Find Blindness Preventions, Treatments and Cures for Retinal Diseases ------------------------------------------------------------------------ Raritan Valley $15,000 Galileo Scholarships: Providing Community College Access to STEM Education Foundation ------------------------------------------------------------------------ Raritan Valley $10,000 Preparing for the Next Community College Generation Science Standards Foundation ------------------------------------------------------------------------ Arbor Day Foundation $5,305 Trees in Celebration-Green Printing Initiative ------------------------------------------------------------------------ Rutgers University $125,000 Health Outcomes, Policy, and Foundation Economics ------------------------------------------------------------------------ Arrow Lake Foundation $146,722 General Mission Support ------------------------------------------------------------------------ Bill, Hillary, and $50,000 National Health Transformation Chelsea Clinton Foundation ------------------------------------------------------------------------ Regents of the $25,000 V-BID University of Michigan ------------------------------------------------------------------------ The Medical College of $1,265 CIBMTR General Operating Wisconsin, Inc. Support ------------------------------------------------------------------------ ALL IN TOGETHER $37,500 All in Together Campaign: CAMPAIGN INC. Advancing and Empowering Women Leaders ------------------------------------------------------------------------ Childrens Inn at NIH $500,000 Sanofi US Legacy Endowment Fund Inc. at The Children's Inn at NIH ------------------------------------------------------------------------ Kids Corporation II $10,000 Kids Corp General Operating ------------------------------------------------------------------------ American Cancer $25,000 Nationwide Hope Lodge Society Cancer Action Partnership Network ------------------------------------------------------------------------ Boy Scouts of America, $1,000 STEM Scouts, BSA Catalina Council ------------------------------------------------------------------------ Kino Learning Center $2,000 STEM Funding Inc. ------------------------------------------------------------------------ SARSEF-SOUTHERN $5,000 Finding the Next Generation of ARIZONA RESEARCH STEM Researchers SCIENCE AND ENGINEERING FOUNDATION ------------------------------------------------------------------------ International Myeloma $19,640 International Myeloma Foundation Foundation Mission Support ------------------------------------------------------------------------ International Myeloma $2,000 MMJP Donation to Support the Foundation International Myeloma Foundation ------------------------------------------------------------------------ $6,715,031 Total 2016 Sanofi $352,310,932 US ------------------------------------------------------------------------ Payments made by Sanofi US (2017) ------------------------------------------------------------------------ Legal Name Payment Amount Project Title ------------------------------------------------------------------------ AAALAC International $2,500.00 IQ Consortium/AAALAC International Global 3Rs Awards Program ------------------------------------------------------------------------ Academy of Managed $30,000.00 2017 AMCP Partnership Forums Care Pharmacy ------------------------------------------------------------------------ Academy of Nutrition $18,000.00 DCE On the Cutting Edge and Dietetics on newsletter behalf of Diabetes Care and Education ------------------------------------------------------------------------ ALL IN TOGETHER $25,000.00 National Women's Leadership CAMPAIGN INC. Initiative ------------------------------------------------------------------------ Alliance for Patient $150,000.00 Keep My Rx Campaign Access ------------------------------------------------------------------------ Alliance for the $50,000.00 Webinars on Nonmedical Adoption of Switching of Diabetes Innovations in Patients Medicine (Aimed Alliance) ------------------------------------------------------------------------ Alliance for the $42,000.00 Campaign to End Nonmedical Adoption of Switching of Diabetes Innovations in Patients Medicine (Aimed Alliance) ------------------------------------------------------------------------ American Academy of $250,000.00 Practice Management Center Dermatology Inc ------------------------------------------------------------------------ American Association $25,000.00 AACE 26th Annual Scientific & of Clinical Clinical Congress General Endocrinologists Support ------------------------------------------------------------------------ American Association $150,035.00 AACE Multi-Site Proposal to of Clinical Extend the Endocrinologists Transculturalization of Diabetes Care ------------------------------------------------------------------------ American Association $75,000.00 AADE Access and Affordability of Diabetes Forum Educators ------------------------------------------------------------------------ American Association $20,000.00 2017 Public Policy Forum of Diabetes Educators ------------------------------------------------------------------------ American Cancer $2,500.00 RUN FOR DAD Society ------------------------------------------------------------------------ American Cancer $10,000.00 ACS CAN State Government Society Cancer Relations Director Training Action Network and Advocacy Activities Nationwide ------------------------------------------------------------------------ American Cancer $25,000.00 2017 ACS CAN Fundraising Society Cancer Events and ACS CAN advocacy Action Network activities ------------------------------------------------------------------------ American Cancer $2,500.00 Relay For Life of Bridgewater Society Inc. ------------------------------------------------------------------------ American Chemical $3,000.00 Division of Medicinal Society Division of Chemistry Program 253rd ACS Medicinal Chemistry national meeting ------------------------------------------------------------------------ American Chemical $2,500.00 ACS MEDI-EFMC Frontiers in Society Division of Medicinal Chemistry 2017 Medicinal Chemistry ------------------------------------------------------------------------ American Chemical $3,000.00 Division of Medicinal Society Division of Chemistry Program 254th ACS Medicinal Chemistry National Meeting ------------------------------------------------------------------------ American College of $100,000.00 Heart House Roundtable: Cardiology Effective Prior Authorization Foundation ------------------------------------------------------------------------ American College of $100,000.00 ACC's 2017 LDL: Address the Cardiology Risk Think Tank Foundation ------------------------------------------------------------------------ American College of $20,000.00 Donald C. Jones Leadership and Endocrinology Endocrine Excellence Award ------------------------------------------------------------------------ American College of $2,000.00 Expand the body of knowledge Laboratory Animal in the fields of laboratory Medicine animal science and medicine ------------------------------------------------------------------------ American College of $1,500.00 2017 ACT Corporate Membership Toxicology ------------------------------------------------------------------------ American Diabetes $2,500.00 Tour de Cure Hawaii--Hele On Association Hawaii ------------------------------------------------------------------------ American Diabetes $2,500.00 American Diabetes Month-- Association Malama Ohana ------------------------------------------------------------------------ American Diabetes $2,500.00 2017 RVA Tour de Cure & Association Fitness Walk ------------------------------------------------------------------------ AMERICAN DIABETES $2,000,000.00 Pathway to Stop Diabetes ASSOCIATION INC. ------------------------------------------------------------------------ American Drug $20,000.00 American Drug Utilization Utilization Review Review Symposium Society ------------------------------------------------------------------------ American Foundation $25,000.00 2017 Get in Rhythm. Stay in for Women's Health Rhythm. Atrial Fibrillation (dba StopAfib.org) Patient Conference ------------------------------------------------------------------------ American Friends of $15,000.00 Scholarship Fundraising Event-- Toulouse School of Toulouse School of Economics Economics Inc Gala Event ------------------------------------------------------------------------ American Heart $25,000.00 2017 National Health Tech & Association Innovation Forum ------------------------------------------------------------------------ American Heart $30,000.00 Boston Heart & Stroke Ball Association Sponsor ------------------------------------------------------------------------ American Heart $15,000.00 Heart Innovation Forum Association Inc ------------------------------------------------------------------------ American Medical $50,000.00 AMSSM Research Grant Awards Society for Sports Program Medicine Foundation, Inc. ------------------------------------------------------------------------ American Medical $25,000.00 Multi-Site CRN OA Grant with Society for Sports Shark Tank competition Medicine Foundation, Inc. ------------------------------------------------------------------------ American Orthopaedic $55,000.00 Early Osteoarthritis and Society for Sports Prevention of OA Progression Medicine ------------------------------------------------------------------------ American Pharmacists $75,000.00 Osteoarthritis Pharmacist- Association Patient Companion Guide ------------------------------------------------------------------------ American Pharmacists $80,000.00 Osteoarthritis Pharmacist Quiz Association Platform ------------------------------------------------------------------------ American Society for $10,000.00 4th Annual ASBMT Fall Clinical Blood and Marrow Education Conference Transplantation ------------------------------------------------------------------------ American Society for $2,500.00 ASN Annual Meeting Neurochemistry ------------------------------------------------------------------------ American Society for $1,500.00 Myelin Satellite Meeting Neurochemistry ------------------------------------------------------------------------ American Society for $70,000.00 2017 Town Hall Presentation Preventive Series Cardiology ------------------------------------------------------------------------ American Society of $35,000.00 Kidney Week 2017--Sponsorships Nephrology ------------------------------------------------------------------------ American Society of $75,000.00 2018 Corporate Sponsor Transplant Surgeons Foundation ------------------------------------------------------------------------ American Statistical $1,000.00 ASA Princeton-Trenton chapter Association of 2017 Spring Symposium Princeton-Trenton Chapter ------------------------------------------------------------------------ Americans for Medical $7,500.00 Raising Voices, Saving Lives Progress Educational Foundation ------------------------------------------------------------------------ Americares $12,000.00 Air Lift Benefit Sponsorship 2017 ------------------------------------------------------------------------ Americares $70,000.00 Sanofi Solar Power Puerto Rico Concept ------------------------------------------------------------------------ AMGA Foundation Inc $175,000.00 Together 2 Goal diabetes campaign ------------------------------------------------------------------------ Amigos Together For $5,000.00 Domino Night Gala for After Kids, Inc. d/b/a School Program, Nurturing Amigos For Kids Parent Program and Blue Ribbon Campaign ------------------------------------------------------------------------ Arizona Diabetes $3,000.00 Diabetes: A Prescription for Foundation Care ------------------------------------------------------------------------ Arkansas Pharmacy $1,000.00 Immunization Summit Foundation ------------------------------------------------------------------------ Arthritis Foundation $1,200.00 2017 Delaware Bone Bash ------------------------------------------------------------------------ Asian American Legal $10,000.00 2017 Justice in Action Awards Defense and Gala Education Fund ------------------------------------------------------------------------ Association of $7,500.00 Sponsorship of Health American Medical Workforce Research Conference Colleges ------------------------------------------------------------------------ Association of Black $25,000.00 Improving Healthcare Access Cardiologists for Minority and High Risk Population Gala Dinner ------------------------------------------------------------------------ Association of Black $100,000.00 ABC Advocacy Training Program Cardiologists ------------------------------------------------------------------------ Association of $5,000.00 AUTM 2017 Annual Meeting University Sponsorship Technology Managers Inc. ------------------------------------------------------------------------ Asthma & Allergy $1,000.00 Asthma Coalition Meeting Foundation of America, St. Louis Chapter ------------------------------------------------------------------------ Austin Black $2,500.00 Austin Black Physicians Physicians Association Scholarship Association Fundraiser ------------------------------------------------------------------------ Autoimmune Advocacy $2,500.00 Living with Autoimmunity Alliance ------------------------------------------------------------------------ Be The Match $37,500.00 Be The Match Walk+Run National Foundation Sponsorship ------------------------------------------------------------------------ Biocom $10,000.00 Global Life Science Partnering Conference ------------------------------------------------------------------------ BIONJ INC. $10,000.00 2017 Annual Dinner Meeting ------------------------------------------------------------------------ BIONJ INC. $2,500.00 2017 bioNJ BioPartnering Conference ------------------------------------------------------------------------ Biotechnology $195,000.00 2017 BIO International Innovation Convention Sponsorship Organization ------------------------------------------------------------------------ Biotechnology $25,000.00 2017 BIO Europe Spring Innovation Sponsorship Organization ------------------------------------------------------------------------ Biotechnology $25,000.00 2017 BIO Europe Sponsorship-- Innovation November Organization ------------------------------------------------------------------------ Biotechnology $10,000.00 2017 BIO Patient and Health Innovation Advocacy Summit Organization ------------------------------------------------------------------------ Biotechnology $57,500.00 2018 BIO International Innovation Convention Organization ------------------------------------------------------------------------ Blood and Marrow $25,000.00 Celebrating a Second Chance at Transplant Life 2017 Survivorship Information Network Symposium ------------------------------------------------------------------------ Brigham and Women's $2,000.00 PKD symposium Hospital ------------------------------------------------------------------------ Cancer Support $8,000.00 Bringing Multiple Myeloma Community Journey Partners to the Cancer Support Community ------------------------------------------------------------------------ CANCER SUPPORT $5,000.00 2017 Wings of Hope COMMUNITY CENTRAL NEW JERSEY ------------------------------------------------------------------------ CANCER SUPPORT $2,500.00 Inspiring Hope Advocate COMMUNITY CENTRAL Sponsorship NEW JERSEY ------------------------------------------------------------------------ CASSS $2,500.00 6th International Symposium on Higher Order Structure of Protein Therapeutics (HOS 2017) ------------------------------------------------------------------------ CASSS $2,500.00 WCBP 2017: 21st Symposium on the Interface of Regulatory and Analytical Sciences for Biotechnology Health Products ------------------------------------------------------------------------ CASSS $2,500.00 Advances in the Biotechnology & Pharmaceutical Industries: 19th Symposium on the Practical Applications for the Analysis of Proteins, Nucleotides and Small Molecules ------------------------------------------------------------------------ CASSS $2,500.00 14th Symposium on the Practical Application of Mass Spectrometry in the Biotechnology Industry ------------------------------------------------------------------------ CASSS $2,500.00 Analytical Technologies in the Biopharmaceutical Industry (AT Europe 2017) ------------------------------------------------------------------------ CASSS $2,500.00 Bioassays 2017 ------------------------------------------------------------------------ Catalyst Inc. $13,500.00 Catalyst International Women's Day Gala Dinner ------------------------------------------------------------------------ Chicago Hispanic $500.00 Vive tu Vida!Get up! Get Health Coalition moving! Health and Wellness Fair ------------------------------------------------------------------------ Children's Health $30,000.00 Children's Health Fund 2017 Fund Annual Benefit ------------------------------------------------------------------------ Children's Health $665,000.00 Medical Home Initiative Fund ------------------------------------------------------------------------ Children's Health $665,000.00 Medical Home Initiative Fund ------------------------------------------------------------------------ Children's Hospital $10,000.00 2017 PCMM Scientific Retreat Corporation ------------------------------------------------------------------------ Children's Hospital $500.00 Boston Postdoctoral Corporation Association Symposium on Careers and Collaboration in Science ------------------------------------------------------------------------ Christ the King $5,000.00 Annual President's Gala Preparatory School of Newark NJ Corp ------------------------------------------------------------------------ CISCRP $25,000.00 AWARE for All: Clinical Research Education Day ------------------------------------------------------------------------ CISCRP $160,000.00 AWARE for All Campaign ------------------------------------------------------------------------ Coalition for $5,000.00 Health RX: Building Affordable Health Affordability & Access event Coverage sponsorship ------------------------------------------------------------------------ Coastal Volunteers in $1,000.00 Care & Management of Diabetic Medicine Patients ------------------------------------------------------------------------ Cold Spring Harbor $15,000.00 Cold Spring Harbor Laboratory Laboratory Corporate Sponsor Program 2017 ------------------------------------------------------------------------ College Diabetes $55,000.00 CDN Political Advocacy for Network Inc. Young Adults Guide ------------------------------------------------------------------------ College Diabetes $20,000.00 2017 Corporate Membership Network Inc. ------------------------------------------------------------------------ Colorado Business $7,000.00 Corporate Membership Group on Health ------------------------------------------------------------------------ Community Health $2,500.00 ``Patient-Centered and Coalition, Inc. Population Health for Us'' ------------------------------------------------------------------------ Community Health Task $500.00 2017 World Diabetes Day 5th Force, Inc. Annual BridgeWalk for Diabetes Awareness and Care ------------------------------------------------------------------------ Community Hope, Inc. $4,800.00 Veterans Pre-Holiday Dinner and Gift Cards ------------------------------------------------------------------------ Community Hope, Inc. $10,000.00 2017 Corporate Partner Program ------------------------------------------------------------------------ Community Oncology $25,000.00 2017 Payer Exchange Summit VII Alliance ------------------------------------------------------------------------ Conference of Western $5,000.00 CWAG 2017 Chair Initiative Attorneys General Sponsorship ------------------------------------------------------------------------ Congress of $2,500.00 Adherence Outreach and California Seniors Education with Seniors = Education and Script your Future Research Fund ------------------------------------------------------------------------ Council for the $60,000.00 10th World Conference of Advancement of Science Journalists Science Writing, Inc. ------------------------------------------------------------------------ CrowdCare Foundation, $20,000.00 Muscles for Myeloma Inc. ------------------------------------------------------------------------ CSweetener $25,000.00 CSweetener Mentoring Program ------------------------------------------------------------------------ Deep South Cancer $5,000.00 Cycliad 2017 Foundation ------------------------------------------------------------------------ Deirdre O'Brien Child $5,000.00 21st Annual Gala Solicitation Advocacy Center Inc. ------------------------------------------------------------------------ Diabetes Foundation $1,000.00 Tastings & Tapas Fundraiser Inc. ------------------------------------------------------------------------ Diabetes Foundation $2,500.00 Live-A-Betes: Living Well with of Mississippi Diabetes ------------------------------------------------------------------------ Diversity Alliance $5,500.00 DA4S East Coast 2017 for Science, Inc. ------------------------------------------------------------------------ Diversity Alliance $3,500.00 DA4S West Coast 2017 for Science, Inc. ------------------------------------------------------------------------ Donate Life America $26,025.00 Mission Support ------------------------------------------------------------------------ Donate Life Northwest $10,000.00 Part II. Removing Barriers through Knowledge: An Educational Series for Providers of Dialysis and ESRD Patients ------------------------------------------------------------------------ Dress For Success $15,000.00 Transforming Lives Celebration Northern New Jersey-- 10 Counties, Inc. ------------------------------------------------------------------------ Employers Health $7,500.00 2017 Employers Health Coalition, Inc. Innovations in Employee Benefits Conference ------------------------------------------------------------------------ Endocrine Society $150,000.00 Hypoglycemia Quality Improvement Program ------------------------------------------------------------------------ Families of SMA DBA $5,000.00 2017 Annual SMA Conference Cure SMA ------------------------------------------------------------------------ Federal Circuit Bar $2,500.00 Major Regional Program--Boston Association Charitable and Educational Fund ------------------------------------------------------------------------ Federation of $2,000.00 FASEB SRC on the Biology of American Societies Cilia and Flagella for Experimental Biology (FASEB) ------------------------------------------------------------------------ Federation of $25,000.00 FOCIS 2017 Annual Meeting Clinical Immunology Societies ------------------------------------------------------------------------ Florida Health Care $5,000.00 FLHCC 24th Annual National Coalition Conference: Getting to Better Care and Improved Outcomes ------------------------------------------------------------------------ Florida International $170,000.00 Expert Workshop State of the University Art Pertussis Prevention and Foundation Inc. Control in Latin America and the Caribbean ------------------------------------------------------------------------ Florida International $60,000.00 LATIN AMERICAN AND CARIBBEAN University DIABETES NETWORK: A FRAMEWORK Foundation Inc FOR ACTION ------------------------------------------------------------------------ Florida International $60,000.00 Assesment of acellular University vaccination programs in Foundation Inc. Mexico, Costa Rica and Panama ------------------------------------------------------------------------ Florida International $25,000.00 Develop Guidelines for University Antimicrobial Stewardship For Foundation Inc. Latin America and Caribbean region ------------------------------------------------------------------------ Florida International $62,000.00 REVIEW OF NATIONAL University IMMUNIZATION CALENDARS OF THE Foundation Inc. EXPANDED PROGRAM OF IMMUNIZATION (EPI) IN COUNTRIES OF LATIN AMERICA AND THE CARIBBEAN. PRELIMINARY OBSERVATIONS ON FINANCIAL AND FUNDING MECHANISMS OF THE NATIONAL IMMUNIZATION PROGRAMS. ------------------------------------------------------------------------ Food Allergy Research $50,000.00 FARE Patient Registry & Education, Inc. ------------------------------------------------------------------------ Foundation Fighting $100,000.00 Research to Overcome Retinal Blindness Degenerative Diseases ------------------------------------------------------------------------ Foundation for $7,500.00 ANIMAL RESEARCH HELPS ANIMALS Biomedical Research CAMPAIGN ------------------------------------------------------------------------ Foundation of the $20,000.00 Foundation of the National National Lipid Lipid Association Young Association Investigator Abstract Award Program ------------------------------------------------------------------------ French-American $2,500.00 FACC Corporate Membership Chamber of Commerce in the United States, Inc.--New York Chapter ------------------------------------------------------------------------ Friends of Cancer $25,000.00 Exploring New Biomarkers for Research Immunology ------------------------------------------------------------------------ Friends of Cancer $50,000.00 2017 Mission Support Research ------------------------------------------------------------------------ George Washington $130,000.00 The George Washington University University Forum on Arbovirus Infections ------------------------------------------------------------------------ GLBTQ Legal Advocates $3,000.00 18th Annual Spirit of Justice & Defenders Award Dinner ------------------------------------------------------------------------ Good Grief Inc. $7,500.00 2017 Golf ``Fore'' the Kids ------------------------------------------------------------------------ Good Grief Inc. $5,000.00 Great Pumpkin Ball Sponsorship ------------------------------------------------------------------------ Gordon Research $10,000.00 GRC: Pancreatic Diseases Conference ``Exocrine and Endocrine Pancreas: Molecules to Human'' ------------------------------------------------------------------------ Gordon Research $1,000.00 High Throughput Chemistry and Conference Chemical Biology GRC ------------------------------------------------------------------------ Gordon Research $2,500.00 The Enduring Potential of Conference Heterocycles as Synthetic Targets, Cellular Probes, and Drug Candidates ------------------------------------------------------------------------ Gordon Research $2,000.00 2017 Gordon Research Conference Conference on Natural Products & Bioactive Compounds ------------------------------------------------------------------------ Gordon Research $3,000.00 2017 Gordon Research Conference Conference on Medicinal Chemistry ------------------------------------------------------------------------ Gordon Research $3,000.00 Gordon Research Conference and Conference Seminar on ``Lysosomal Diseases'' ------------------------------------------------------------------------ Gordon Research $5,000.00 Gordon Research Conference Conference (GRC) entitled ``Neuroimmune communication in health and disease'' ------------------------------------------------------------------------ Gordon Research $5,000.00 2018 Biology of Spirochetes Conference Gordon Research Conference and Gordon Research Seminar ------------------------------------------------------------------------ Greater Detroit Area $7,000.00 2017 GDAHC Membership Dues Health Council, Inc. ------------------------------------------------------------------------ Greater New England $4,000.00 Economic Development Minority Supplier Sponsorship opportunities Development Council ------------------------------------------------------------------------ Health Action Council $4,500.00 Health Action Council Annual Ohio Event Sponsorship ------------------------------------------------------------------------ HealthCare 21 $25,000.00 Data Impact: Evaluating the Business Coalition Impact of Formulary Exclusion on Pharmacy Data ------------------------------------------------------------------------ Healthcare $3,000.00 2017 Woman of the Year event Businesswomen's Association ------------------------------------------------------------------------ Healthcare $10,000.00 2017 HBA Woman of the Year Businesswomen's event sponsorship Association ------------------------------------------------------------------------ Heart To Heart $15,000.00 25th Anniversary Gala International Inc. ------------------------------------------------------------------------ Heart To Heart $8,500.00 Rutgers Fellows Volunteer International Inc. Service Trip ------------------------------------------------------------------------ Hereditary Disease $2,000.00 2017 Celebration of Discovery Foundation Symposium and Gala ------------------------------------------------------------------------ Horton's Kids, Inc. $15,000.00 Home Runs for Horton's Kids: Comprehensive Programming for At-Risk Children ------------------------------------------------------------------------ Hunterdon Medical $5,000.00 2017 Crystal Ball Sponsorship Center Foundation ------------------------------------------------------------------------ Hyacinth Foundation A $1,000.00 Hyacinth Gala & Silent Auction New Jersey Nonprofit Corporation ------------------------------------------------------------------------ Hyacinth Foundation A $2,500.00 Hyacinth Gala & Silent Auction New Jersey Nonprofit Corporation ------------------------------------------------------------------------ Icahn School of $5,000.00 ISMMS-Sanofi Quantitative Medicine at Mount Systems Pharmacology Sinai Symposium ------------------------------------------------------------------------ ILSI Health and $99,074.00 2017 HESI Membership and Environmental Health Committee Assessments Institute ------------------------------------------------------------------------ Institute for Cancer $10,000.00 2017 In Vino Vita Sponsorship Research dba The Request Research Institute of Fox Chase Cancer Center ------------------------------------------------------------------------ Institute for Safe $1,000.00 20th Annual ISMP Cheers Awards Medication Practices ------------------------------------------------------------------------ International $5,000.00 NIH Oxford-Cambridge 2017 Biomedical Research Global Doctoral Partnerships Alliance Annual Workshop ------------------------------------------------------------------------ International $5,000.00 NIH Oxford-Cambridge 2016 Biomedical Research Global Doctoral Partnerships Alliance Annual Workshop ------------------------------------------------------------------------ International Myeloma $50,000.00 8th International Myeloma Foundation Working Group (IMWG) Summit, Madrid, Spain ------------------------------------------------------------------------ International Myeloma $50,000.00 2017 IMF Patient Programs Foundation ------------------------------------------------------------------------ International Myeloma $50,000.00 International Myeloma Foundation Foundation 2017 Asian Myeloma Network (AMN) Summit ------------------------------------------------------------------------ Iowa Pharmacy $10,000.00 2017 Leadership Pharmacy Association leadership training program Foundation ------------------------------------------------------------------------ JDRF $2,500.00 2017 One Walk Allentown ------------------------------------------------------------------------ JDRF $2,500.00 2017 One Walk Bucks County ------------------------------------------------------------------------ JDRF $2,500.00 2017 One Walk Reading ------------------------------------------------------------------------ JDRF $2,500.00 JDRF Passport to a Cure Gala ------------------------------------------------------------------------ JDRF $2,500.00 Rockin' Docs for Diabetes Cure ------------------------------------------------------------------------ JDRF $2,500.00 2017 One Walk Stroudsburg ------------------------------------------------------------------------ JDRF $2,500.00 2017 One Walk Moosic ------------------------------------------------------------------------ JDRF $2,500.00 2017 One Walk Philadelphia ------------------------------------------------------------------------ JDRF $1,500.00 2017 JDRF One Walk Maine ------------------------------------------------------------------------ JDRF $5,000.00 2017 Triangle Eastern NC OneWalk ------------------------------------------------------------------------ JDRF $10,000.00 2017 Triangle Eastern NC Hope Gala ------------------------------------------------------------------------ JDRF $5,000.00 JDRF One Promise Gala Philadelphia ------------------------------------------------------------------------ JDRF $5,000.00 JDRF One Walk Westmoreland ------------------------------------------------------------------------ JDRF $2,500.00 JDRF One Walk ------------------------------------------------------------------------ JDRF $5,000.00 25th Anniversary JDRF Promise Gala ------------------------------------------------------------------------ JDRF $2,500.00 JDRF TypeOneNation Summit ------------------------------------------------------------------------ JDRF $5,000.00 JDRF Imagine Gala ------------------------------------------------------------------------ JDRF--Western New $3,000.00 Journey to A Cure Gala York Chapter ------------------------------------------------------------------------ JDRF--Western New $2,500.00 Buffalo JDRF One Walk 2017 York Chapter ------------------------------------------------------------------------ JDRF--Western New $5,000.00 Journey to a Cure Gala York Chapter ------------------------------------------------------------------------ JDRF Greater Dallas $2,500.00 JDRF One Walk, Dallas ------------------------------------------------------------------------ JDRF International $2,500.00 JDRF One Walk 2017 ------------------------------------------------------------------------ JDRF International $5,000.00 JDRF 35th Annual Boston Gala ------------------------------------------------------------------------ JDRF INTERNATIONAL $50,000.00 2017 JDRF Government Day ------------------------------------------------------------------------ JDRF International $5,000.00 2017 JDRF One Walk Las Vegas ------------------------------------------------------------------------ JDRF NENY $2,500.00 JDRF Saratoga One Walk ------------------------------------------------------------------------ JDRF NENY $2,500.00 JDRF Albany One Walk ------------------------------------------------------------------------ JDRF New York City $10,000.00 45th annual Promise Ball Chapter ------------------------------------------------------------------------ Jersey Battered $14,000.00 Grand Tastings XXIII Women's Service, Inc. ------------------------------------------------------------------------ Joslin Diabetes $10,000.00 2017 High Hopes Gala Center, Inc. ------------------------------------------------------------------------ Joslin Diabetes $10,000.00 A Taste of Ginger Center, Inc. ------------------------------------------------------------------------ Junior Achievement of $5,000.00 Empowering NJ Students for New Jersey, Inc. Success ------------------------------------------------------------------------ Juvenile Diabetes $5,000.00 2018 Hope for a Cure Gala Research Foundation ------------------------------------------------------------------------ Juvenile Diabetes $2,500.00 2017 JDRF One Walk Southern Research Foundation Tier ------------------------------------------------------------------------ Juvenile Diabetes $2,500.00 2017 Hope for a Cure Gala Research Foundation ------------------------------------------------------------------------ Juvenile Diabetes $2,500.00 JDRF One Walk Rochester Research Foundation ------------------------------------------------------------------------ Juvenile Diabetes $2,500.00 2017 Rock the Cure Research Foundation ------------------------------------------------------------------------ Juvenile Diabetes $2,500.00 One Walk, Yonkers Research Foundation International ------------------------------------------------------------------------ Keystone Symposia on $50,000.00 Keystone Symposia Directors' Molecular and Fund Cellular Biology ------------------------------------------------------------------------ Keystone Symposia on $25,000.00 Keystone Symposia Directors' Molecular and Fund Cellular Biology ------------------------------------------------------------------------ Lake Norman Community $2,500.00 Sunset and Sandals Health Clinic ------------------------------------------------------------------------ Lymphoma Research $2,000.00 10th Annual Love to Find a Foundation Cure Dinner ------------------------------------------------------------------------ Machestic Dragons $5,000.00 2017 Machestic Dragons `` `Paddle for Pink' Community Dragon Boat Festival'' ------------------------------------------------------------------------ Machestic Dragons $500.00 2017 Machestic Dragons `` `Paddle for Pink' Community Dragon Boat Festival'' ------------------------------------------------------------------------ Map International $10,000.00 Bill Foege Event Sponsorship ------------------------------------------------------------------------ March of Dimes $2,500.00 Signature Chefs--Seattle Foundation ------------------------------------------------------------------------ Massachusetts General $1,500.00 18th Annual Paul S. Russell Hospital--Transplant Lecture in Transplantation Center ------------------------------------------------------------------------ Massachusetts $5,000.00 Immune Engineering Symposium Institute of 2017 Technology ------------------------------------------------------------------------ Massachusetts $5,000.00 Immune Engineering Symposium Institute of 2017 Technology ------------------------------------------------------------------------ Massachusetts $5,000.00 Koch Institute Summer Institute of Symposium 2017 Technology ------------------------------------------------------------------------ Massachusetts Society $1,000.00 MSMR Annual Meeting of Members for Medical Research, Inc. ------------------------------------------------------------------------ MassChallenge, Inc. $50,000.00 PULSE@MassChallenge 2018 Sanofi Gold Sponsorship ------------------------------------------------------------------------ Medical Foundation of $10,000.00 Osteoarthritis Action Alliance North Carolina Inc (OAAA) Community mini-grant Program ------------------------------------------------------------------------ Men's Health Network $25,000.00 Men's Health Month Sponsorship ------------------------------------------------------------------------ Mercy Health $2,500.00 Stick it to Diabetes Foundation Joplin ------------------------------------------------------------------------ Mercy Health $2,500.00 Mercy Gala of Hope Foundation--Springfi eld ------------------------------------------------------------------------ Metabolic Endocrine $25,000.00 15th Annual World Congress on Education Foundation Insulin Resistance Diabetes and Cardiovascular Disease WCIRDC ------------------------------------------------------------------------ Metabolic Endocrine $100,000.00 1st Annual Congress--Heart in Education Foundation Diabetes (HiD) ------------------------------------------------------------------------ Metabolic Endocrine $25,000.00 15th Annual World Congress on Education Foundation Insulin Resistance Diabetes and Cardiovascular Disease-- WCIRDC = Request 2 ------------------------------------------------------------------------ Mid-America Coalition $5,000.00 5th Annual Workforce & on Health Care Community Well-Being Forum ------------------------------------------------------------------------ Middle Atlantic $1,000.00 Bradford award/student career Reproduction and event Teratology Association (MARTA) ------------------------------------------------------------------------ Moses E. Cheeks Slam $2,500.00 Chicago Camp Slam Dunk for Dunk for Diabetes Diabetes ------------------------------------------------------------------------ Multiple Myeloma $20,000.00 Stem Cell Care Package Program Research Foundation and Re Birthday Program ------------------------------------------------------------------------ Multiple Myeloma $20,000.00 Multiple Myeloma Patient Research Foundation Summits ------------------------------------------------------------------------ Myotonic Dystrophy $3,000.00 2017 MDF Conference Foundation Sponsorship ------------------------------------------------------------------------ NASPA $5,000.00 OA Mobility Discussion and Event ------------------------------------------------------------------------ NATIONAL ACADEMY OF $50,000.00 Forum on Neuroscience and SCIENCES Nervous System Disorders ------------------------------------------------------------------------ NATIONAL ACADEMY OF $85,000.00 Forum on Drug Discovery, SCIENCES Development and Translation ------------------------------------------------------------------------ National Alliance of $17,000.00 Supporting Employers to Healthcare Purchaser Effectively Manage Rheumatoid Coalitions Arthritis Action Brief ------------------------------------------------------------------------ National Alliance of $2,000.00 13th Annual Meeting of NASPCC State Prostate Cancer Coalitions ------------------------------------------------------------------------ National Bone Marrow $5,000.00 PEER SUPPORT FOR BONE MARROW, Transplant Link STEM CELL TRANSPLANT COMMUNITY ------------------------------------------------------------------------ National Bone Marrow $2,500.00 Resource Directory Transplant Link ------------------------------------------------------------------------ National Committee $10,000.00 NCQA's Quality Talks 2017 for Quality Assurance (``NCQA''') ------------------------------------------------------------------------ National $10,000.00 NCCN 12th Annual Congress: Comprehensive Cancer Hematologic Malignancies Network Patient Advocacy Pavilion ------------------------------------------------------------------------ National Eczema $50,000.00 National Eczema Association's Association Grassroots Advocacy Program ------------------------------------------------------------------------ National Forum for $25,000.00 National Forum Cholesterol Heart Disease and Initiative (Phase 3) Stroke Prevention Inc. ------------------------------------------------------------------------ National Forum for $25,000.00 National Forum Value & Access Heart Disease and Initiative Stroke Prevention Inc. ------------------------------------------------------------------------ National Health $130,000.00 Patient Perspective on the Council Value of Treatments ------------------------------------------------------------------------ National Hispanic $5,000.00 Diabetes and Renal Disease Medical Association among Latino Patients Conference ------------------------------------------------------------------------ National Kidney $1,000.00 2017 Champion of Hope Tribute Foundation of Dinner Michigan ------------------------------------------------------------------------ National Kidney $50,000.00 Connecting Diabetes, Foundation, Inc. Cardiovascular Disease, and Kidney Disease `` Patient Awareness Campaign ------------------------------------------------------------------------ National Lipid $30,000.00 Expansion of Discovering the Association Barriers to Access of PCSK9 Inhibitors: an NLA Assessment ------------------------------------------------------------------------ National Minority $25,000.00 Diabetes Working Group: Vision Quality Forum 20/20 ------------------------------------------------------------------------ National TB $5,000.00 Sponsorship for the 2017 Controllers National TB Conference: Association Poster Discussion ------------------------------------------------------------------------ NCSL Foundation for $7,500.00 NCSL LegisBrief Sponsorship State Legislatures ------------------------------------------------------------------------ New England $5,000.00 New England Immunology Immunology Conference Conference, Inc. ------------------------------------------------------------------------ New Jersey Public $500.00 New Jersey Public Health Health Association Association 2017 Annual Conference ------------------------------------------------------------------------ New Jersey Society of $5,000.00 Sponsorship/Membership Oncology Managers ------------------------------------------------------------------------ New York & New Jersey $10,000.00 Annual Event Sponsorship Minority Supplier Development Council ------------------------------------------------------------------------ NewYorkBIO $8,000.00 NewYorkBIO 2017 Annual Conference ------------------------------------------------------------------------ NJ AIDS Services $2,500.00 New Jersey AIDS Walk ------------------------------------------------------------------------ North Eastern Section $2,000.00 6th Advances in Chemical Of American Chemical Sciences Society ------------------------------------------------------------------------ NorthCrest Medical $2,500.00 NorthCrest Gala Center Foundation ------------------------------------------------------------------------ Northeast Business $20,000.00 eValue8--Health Plan Group on Health Performance Assessment ------------------------------------------------------------------------ NYU School of $5,000.00 The Skirball Institute 18th Medicine, an Symposium Honoring Dan administrative unit Littman, MD of New York University ------------------------------------------------------------------------ Ohio Chamber of $1,250.00 2017 Salt Fork Policy Commerce Conference ------------------------------------------------------------------------ Operation Jersey $500.00 Gala of Giving II Cares ------------------------------------------------------------------------ Operation Warrior $10,000.00 2017 Army Navy Game Wishes Foundation ------------------------------------------------------------------------ Oregon State $7,500.00 OSU College of Pharmacy, University Pharmacy Partners Program Foundation ------------------------------------------------------------------------ Organization for $15,000.00 2017 OFII Annual Dinner International Investment ------------------------------------------------------------------------ Out & Equal $25,000.00 2017 Workplace Summit ------------------------------------------------------------------------ Patient Advocate $5,000.00 16th Annual A Promise of Hope Foundation Affair ------------------------------------------------------------------------ Patient Advocate $250,000.00 Patient Advocate Foundation Co- Foundation Pay Relief Program Oncology Donation ------------------------------------------------------------------------ PATIENT EMPOWERMENT $25,000.00 Virtual Town Meeting for NETWORK Advanced Prostate Cancer Patients ------------------------------------------------------------------------ Patient Services Inc. $5,000.00 PSI Advocacy Day and Congressional Reception ------------------------------------------------------------------------ PCMA $80,000.00 2017 sPCMA Business Forum Sponsorship, Presidential ------------------------------------------------------------------------ PCMA $95,000.00 2017 Annual Meeting Presidential Sponsorship ------------------------------------------------------------------------ Pharmaceutical $270,000.00 PhRMA Foundation Grants & Research and Fellowships Manufacturers of America Foundation ------------------------------------------------------------------------ PQA, Inc. $7,500.00 PQA 2017 Leadership Summit: Connecting the Dots to Enhance Patient Care ------------------------------------------------------------------------ PQA, Inc $100,000.00 An Accelerated Strategy for Advancing an Insulin Adherence/Persistence Quality Measure ------------------------------------------------------------------------ Preventive $50,000.00 Access to Innovative Medicine Cardiovascular Campaign Nurses Association ------------------------------------------------------------------------ Pro Bono Partnership $15,000.00 Pro Bono Partnership 2017 Gala ------------------------------------------------------------------------ Project Hope The $10,000.00 2017 Gala--Project HOPE: A People To People Voice for Global Health Health Foundation Inc. ------------------------------------------------------------------------ Prostate Cancer $10,000.00 Chemotherapy Patient Education Education Council ------------------------------------------------------------------------ Prostate Cancer $25,000.00 Interactive Patient Education Education Council Programs ------------------------------------------------------------------------ Prostate Cancer $300,000.00 24th Annual Scientific Retreat Foundation ------------------------------------------------------------------------ Public Health $5,000.00 Building Health Equity in Advocates Diabetes Prevention and Treatment Conference ------------------------------------------------------------------------ Raritan Valley $3,000.00 College Campus Experience Community College Sessions for STEM High School Foundation Students ------------------------------------------------------------------------ Raritan Valley $10,000.00 Preparing for the Next Community College Generation Science Standards-- Foundation District Partnership Program ------------------------------------------------------------------------ Raritan Valley $125,000.00 Sanofi Nursing Simulation Lab: Community College Preparing Nursing Students to Foundation Meet the Community's Health Care Needs ------------------------------------------------------------------------ Raritan Valley $25,000.00 Galileo Scholarships: Community College Providing Access to STEM Foundation Education ------------------------------------------------------------------------ Raritan Valley $46,100.00 Sanofi US Corporate Mentor Community College Program at RVCC Foundation ------------------------------------------------------------------------ Raritan Valley $3,250.00 An Evening of Elegance for Community College Education Foundation ------------------------------------------------------------------------ Raritan Valley $10,000.00 Preparing for the Next Community College Generation Science Standards Foundation ------------------------------------------------------------------------ Raritan Valley $15,000.00 Galileo Scholarships: Community College Providing Access to STEM Foundation Education ------------------------------------------------------------------------ Regents University of $10,000.00 March Kidney Fair, March 26, California Los 2017 Angeles ------------------------------------------------------------------------ Research!America $10,000.00 National Health Research Forum ------------------------------------------------------------------------ Research!America $25,000.00 Advocacy Awards Dinner ------------------------------------------------------------------------ RESOURCES USA INC $10,000.00 Bastille Day 2017--Washington DC--Celebrates the Franco- American relationship ------------------------------------------------------------------------ RESOURCES USA INC. $5,000.00 Bastille Day 2017--Boston ------------------------------------------------------------------------ Rutgers University $20,000.00 The Sanofi US Scholarship for Foundation Veterans in the Rutgers Business School Executive Education Program ------------------------------------------------------------------------ Rutgers University $5,000.00 Andrew Giovanni Woman in Foundation Neuroscience Endowed Travel Scholarship ------------------------------------------------------------------------ SDHB Pheo-Para $9,900.00 SDHB Pheo-Para Coalition Gala Coalition, Inc. ------------------------------------------------------------------------ Seeding Labs $2,000.00 Positively Instrumental: 2017 Instrumental Access Launch & Donor Recognition Event ------------------------------------------------------------------------ Society for $25,000.00 Trainee Professional Neuroscience Development Awards at Neuroscience 2017 ------------------------------------------------------------------------ Society of Toxicology $10,000.00 Society of Toxicology (SOT) Annual Meeting ------------------------------------------------------------------------ SOME INC. $5,000.00 2017 SOME Gala ------------------------------------------------------------------------ Somerset Alliance for $1,000.00 NJ Smart Workplace Recognition the Future d.b.a Breakfast RideWise ------------------------------------------------------------------------ Somerset Health Care $2,500.00 Healthier Somerset Foundation ------------------------------------------------------------------------ Springboard 2000 $25,000.00 Health Innovation Hub 2017 Enterprises, Inc. ------------------------------------------------------------------------ State University of $2,500.00 Wellstone Family Conference Iowa Foundation 2017 ------------------------------------------------------------------------ T1 Today, Inc., dba $29,625.00 Round Table on Impact of Non- Children with Medical Switching of Insulin Diabetes ------------------------------------------------------------------------ T1 Today, Inc., dba $48,500.00 Forced Non-Medical Switching Children with Awareness--November 2017 Diabetes ------------------------------------------------------------------------ T1 Today, Inc., dba $20,000.00 Friends for Life Orlando Children with Supporting Sponsorship Diabetes ------------------------------------------------------------------------ T1 Today, Inc., dba $49,500.00 Round Table on Impact of Non- Children with Medical Switching of Insulin-- Diabetes San Diego ------------------------------------------------------------------------ Taking Control of $25,000.00 Educating Patients and Their Your Diabetes Caregivers About The Role Of Treatments In Diabetes Management ------------------------------------------------------------------------ Taking Control of $60,000.00 Taking Control Of Your Your Diabetes Diabetes 2017 ------------------------------------------------------------------------ Taking Control of $20,000.00 ONE: The Ultimate Conference & Your Diabetes Retreat for Adult Type 1's ------------------------------------------------------------------------ TBA Foundation $15,000.00 Pat's Myeloma Survival School ------------------------------------------------------------------------ Teratology Society $1,500.00 Teratology Society 57th Annual Meeting ------------------------------------------------------------------------ THE ALBERT B SABIN $300,000.00 Arbovirus Surveillance VACCINE INSTITUTE Strengthening Phase II INC. ------------------------------------------------------------------------ The American Fallen $5,700.00 2018 Portrait Donation Soldiers Project Inc ------------------------------------------------------------------------ The American Heart $25,000.00 American Heart Association Association Multicultural Initiatives ------------------------------------------------------------------------ The American Heart $50,000.00 Go Red for Women; Health Association Education Symposium ------------------------------------------------------------------------ The American Heart $25,000.00 Heart and Stroke Ball Campaign Association 2017 ------------------------------------------------------------------------ The American Kidney $50,000.00 The Hope Affair 2017--Imagine Fund, Inc. the Possibilities ------------------------------------------------------------------------ The American Kidney $5,000.00 2017 A Pairing For Prevention Fund, Inc. ------------------------------------------------------------------------ The American Kidney $20,000.00 The Hope Affair Sponsorship Fund, Inc. ------------------------------------------------------------------------ THE BIOBREAK $5,000.00 BioBreak Industry Sponsorship ORGANIZATION INC. ------------------------------------------------------------------------ The Broad Institute, $2,000.00 Glom-NExT3 Symposium Inc. ------------------------------------------------------------------------ The Center For Great $5,000.00 2017 Gift of Hope Gala Expectations Inc. ------------------------------------------------------------------------ The Children's Aid $25,000.00 Children's Aid Keeping the Society Promise Benefit ------------------------------------------------------------------------ The Children's $2,000.00 2017 Conference on Clinical Hospital of Trial Readiness in the Philadelphia Leukodystrophies ------------------------------------------------------------------------ The Children's $2,000.00 2017 Conference on Clinical Hospital of Trial Readiness in the Philadelphia Leukodystrophies ------------------------------------------------------------------------ The Children's Inn at $10,000.00 An Evening for Hope NIH, Inc. ------------------------------------------------------------------------ The Council of State $5,000.00 Bowhay Institute for Government, Ltd. Legislative Leadership Development ------------------------------------------------------------------------ The Diabetes $2,500.00 Giving Diabetes the Blues Coalition of Mississippi/ Mississippi Rural Health Association ------------------------------------------------------------------------ The diaTribe $50,000.00 Consensus Conference Glycemic Foundation Outcomes Beyond A1C ------------------------------------------------------------------------ The diaTribe $20,000.00 11th Annual Diabetes Forum Foundation ------------------------------------------------------------------------ The diaTribe $90,000.00 Follow Up for d17: Executive Foundation Innovation Lab in Diabetes and Prediabetes ------------------------------------------------------------------------ The Economic Alliance $2,500.00 EAM Health Purchaser Forum for Michigan ------------------------------------------------------------------------ The FH Foundation $250,000.00 The CASCADE FHTM Registry ------------------------------------------------------------------------ The FH Foundation $100,000.00 Advocates for Awareness ------------------------------------------------------------------------ The FH Foundation $75,000.00 2017 FH Global Summit ------------------------------------------------------------------------ The Galien Foundation $15,000.00 PRIX GALIEN USA GALIEN FORUM ------------------------------------------------------------------------ The Health $5,000.00 Inspire Sponsorship Collaborative ------------------------------------------------------------------------ THE LEUKEMIA & $50,000.00 Blood and Marrow Stem Cell LYMPHOMA SOCIETY Transplantation Booklet and Guide ------------------------------------------------------------------------ The Medical College $10,000.00 2017 BMT Tandem Meetings-- of Wisconsin, Inc. Administrative Directors Reception ------------------------------------------------------------------------ The Mended Hearts, $25,000.00 Patient Advocacy Network (PAN) Inc. Training ------------------------------------------------------------------------ The Mended Hearts, $10,000.00 National Education & Training Inc. Conference ------------------------------------------------------------------------ The Mesothelioma $2,000.00 Sponsorship--Clinical Trial Applied Research Awareness Foundation ------------------------------------------------------------------------ The New York Academy $5,000.00 Challenge 2030: Tomorrow's of Science innovators tackle today's grand challenges ------------------------------------------------------------------------ The Ohio State $25,000.00 Pharmacy Patient Counseling University Education Foundation ------------------------------------------------------------------------ The Ohio State $1,000.00 Pharmathon 5k University Foundation ------------------------------------------------------------------------ The Partnership for $5,000.00 PQMD London Educational Forum Quality Medical Donations ------------------------------------------------------------------------ The Pennsylvania $150,000.00 SARP SUPPLEMENTAL FUNDING State University AGREEMENT ------------------------------------------------------------------------ THE TRANSPLANTATION $7,500.00 The 14th Congress of the SOCIETY International Xenotransplantation Association ------------------------------------------------------------------------ THE TRANSPLANTATION $15,000.00 9th Congress of the SOCIETY International Pediatric Transplant ------------------------------------------------------------------------ The Virginia Public $700.00 Lighten Up, It's Just Politics Access Project ------------------------------------------------------------------------ The World Orphan Fund $500.00 2017 Annual Wisconsin Gala Inc. ------------------------------------------------------------------------ Thomas Jefferson $65,000.00 Population Health Leadership University Series (formerly Quality and Safety Leadership Series) ------------------------------------------------------------------------ Thomas Jefferson $100,000.00 Quality and Safety Leadership University Series ------------------------------------------------------------------------ Tree Canada $14,089.00 Operation ReLeaf Fort McMurray ------------------------------------------------------------------------ Trustees of Boston $65,000.00 National Association of University Community Health Workers Communications and Organizational Development Project ------------------------------------------------------------------------ Trustees of Boston $1,000.00 Boston University's 16th University Annual CMD Symposium on Molecular Discovery: From Chemical Synthesis to Biological Applications ------------------------------------------------------------------------ Trustees of Boston $20,000.00 iHEA's 12th World Congress in University Health Economics ------------------------------------------------------------------------ Trustees of $5,000.00 Translational Retinal Research University of & Therapies 2017 Symposium Pennsylvania ------------------------------------------------------------------------ Tufts Center for the $30,000.00 Tufts CSDD 2017 Sponsorship Study of Drug Development c/o Trustees of Tufts College ------------------------------------------------------------------------ TULANE CANCER CENTER $2,500.00 NOLA Bluedoo 2017 ------------------------------------------------------------------------ University of Florida $5,000.00 11th Annual Clinical Pharmacy Foundation and Pharmacology Symposium ------------------------------------------------------------------------ University of $5,000.00 UMN John S. Najarian Lecture & Minnesota Foundation 50 Years of Pancreas Symposium ------------------------------------------------------------------------ University of New $1,000.00 2017 Hoops4Hope Legislative Mexico Foundation = Basketball Game Hoops for Hope ------------------------------------------------------------------------ University of North $20,000.00 Pharmacoepidemiology Program Carolina at Chapel Hill ------------------------------------------------------------------------ University of $10,000.00 Unity 2017 Conference Southern Mississippi Foundation ------------------------------------------------------------------------ University of Texas $50,000.00 Third Annual International Foundation-UT Austin Immuno-Therapy in Myeloma Scientific Workshop ------------------------------------------------------------------------ University of Utah $50,000.00 2017 Western Atrial Fibrillation Symposium ------------------------------------------------------------------------ Us TOO International $15,000.00 Prostate Cancer Support Group Meeting Webcast ------------------------------------------------------------------------ Us TOO International $20,000.00 Prostate Cancer News You Can Use ------------------------------------------------------------------------ Virginia Bio $3,000.00 Women Building Bio--the XX Factor ------------------------------------------------------------------------ Virginia Quality $1,000.00 VQHN Eighteenth Annual Wrap Up Healthcare Network Event ------------------------------------------------------------------------ Vision y Compromiso $10,000.00 Vision y Compromiso's 15th Annual Conference for Promotoras and CHWs, ``Resiliency: Our Strength in Times of Change'' ------------------------------------------------------------------------ Waltham West Suburban $6,000.00 Waltham West Suburban Chamber Chamber of Commerce, of Commerce Sponsorship Inc. Opportunities ------------------------------------------------------------------------ Washington Legal $30,000.00 2017 General Operating Support Foundation ------------------------------------------------------------------------ Washington Policy $3,500.00 2017 Annual Dinner Center ------------------------------------------------------------------------ Western Governors' $10,000.00 2017-2018 Bi-annual Foundation Conferences ------------------------------------------------------------------------ Women In Government $5,000.00 2017 Healthcare Summit-- Foundation, Inc. Inspiration Station ------------------------------------------------------------------------ Women In Government $65,000.00 2017 Healthcare Summit-- Foundation, Inc. Diabetes PSAs ------------------------------------------------------------------------ WomenHeart: The $25,000.00 2017 Wenger Awards National Coalition for Women with Heart Disease ------------------------------------------------------------------------ WomenHeart: The $45,000.00 Access NOW! Key Opinion National Coalition Leaders Thought Workshop & for Women with Heart Congressional Briefing Disease ------------------------------------------------------------------------ Wyoming Congressional $5,000.00 WY Congressional Award Award Council Council's Spring Awards ceremony ------------------------------------------------------------------------ ZERO--The End of $8,000.00 Chemotherapy and Immunotherapy Prostate Cancer Sequencing in Prostate Cancer Webinar ------------------------------------------------------------------------ $13,245,248.00 ------------------------------------------------------------------------ Product Donations $594,228,133 made by Sanofi US to the Sanofi Foundation for North Americaestimate as of March 2018) ------------------------------------------------------------------------ Donations made by the Sanofi Foundation for North America ------------------------------------------------------------------------ Legal Name Payment Amount Project Title ------------------------------------------------------------------------ American Cancer $5,000.00 Hope Lodge of Framingham Society Inc. Operating Support ------------------------------------------------------------------------ American Cancer $25,000.00 Nationwide American Cancer Society Inc. Society Hope Lodge ------------------------------------------------------------------------ American National Red $25,000.00 2017-2018 American Red Cross Cross Biomedical Services ------------------------------------------------------------------------ American Recreational $3,200.00 Project Homecoming Military Services ------------------------------------------------------------------------ American Red Cross $10,000.00 Disaster Relief & Home Fire Preparedness Campaign ------------------------------------------------------------------------ American Red Cross $177,422.00 Disaster Relief--special employee match ------------------------------------------------------------------------ American Society of $5,000.00 Daniel R. Salomon Frontiers in Transplantation Transplantation Endowment (FITE) ------------------------------------------------------------------------ Americares $50,000.00 Hurricane Maria Response ------------------------------------------------------------------------ Americares $100,000.00 Hurricane Harvey Response ------------------------------------------------------------------------ Americares $10,000.00 U.S. Disaster Assistance ------------------------------------------------------------------------ Camp Nejeda Foundation $5,000.00 Camp Nejeda Campership Program ------------------------------------------------------------------------ Camp Nejeda Foundation $10,000.00 Camp Nejeda: Helping Kids with Type 1 Diabetes Live Happier, Healthier Lives ------------------------------------------------------------------------ Camp Quality USA dba $10,000.00 Camp Quality USA dba Camp Camp Quality NJ Quality NJ ------------------------------------------------------------------------ CANCER SUPPORT $15,000.00 Teens Connect School Based COMMUNITY CENTRAL NEW Support Groups JERSEY ------------------------------------------------------------------------ Children's Health Fund $30,000.00 Asthma Video ------------------------------------------------------------------------ Children's Health Fund $665,000.00 Medical Home Initiative ------------------------------------------------------------------------ Children's Health Fund $665,000.00 Medical Home Initiative ------------------------------------------------------------------------ Christ the King $59,000.00 Christ the King Corporate Work Preparatory School of Study Program Newark NJ Corp. ------------------------------------------------------------------------ Christopher & Dana $5,000.00 Reeve Patient Care & Cures--NJ Reeve Foundation ------------------------------------------------------------------------ Coastal Bend Food Bank $1,000.00 Diabetes Hands On ------------------------------------------------------------------------ Deirdre O'Brien Child $10,000.00 Advocacy Program for Child Advocacy Center Inc. Victims of Abuse and/or Neglect ------------------------------------------------------------------------ Direct Relief $100,000.00 Hurricane Harvey Response ------------------------------------------------------------------------ Direct Relief $50,000.00 Responding to Hurricane Maria in Puerto Rico ------------------------------------------------------------------------ Direct Relief $10,000.00 Emergency Prep Programs ------------------------------------------------------------------------ Dress For Success $5,000.00 General Operating Expenses Northern New Jersey-- 10 Counties, Inc. ------------------------------------------------------------------------ Food Bank of Somerset $12,500.00 Back Pack Program County Inc. ------------------------------------------------------------------------ Heart To Heart $25,000.00 Hurricane Relief Maria International Inc. ------------------------------------------------------------------------ Heart To Heart $10,000.00 US Crisis Relief International Inc. ------------------------------------------------------------------------ Heart To Heart $25,000.00 Hurricane Harvey Response International Inc. ------------------------------------------------------------------------ Hyacinth Foundation A $10,000.00 General Support-Sanofi in Our New Jersey Nonprofit Communities, Celebrating Corporation Diversity ------------------------------------------------------------------------ Hyacinth Foundation A $10,000.00 General Support New Jersey Nonprofit Corporation ------------------------------------------------------------------------ International Myeloma $18,950.00 International Myeloma Foundation Foundation Mission Support ------------------------------------------------------------------------ Jersey Battered $5,000.00 General Operating Women's Service, Inc. ------------------------------------------------------------------------ Kids Corporation II $10,000.00 Kids Corp General Operating ------------------------------------------------------------------------ Map International $10,000.00 MAP's Domestic Medicine Program ------------------------------------------------------------------------ March of Dimes $86,000.00 Supporting NICU Babies and Foundation Family's ------------------------------------------------------------------------ Matheny School and $5,000.00 Matheny Center for Medicine and Hospital Inc. Dentistry ------------------------------------------------------------------------ Matheny School and $5,000.00 Matheny School STEM Program Hospital Inc. ------------------------------------------------------------------------ Midland Adult Services $5,000.00 Midland Helping Hands & Midland Inc. Meals on Wheels Employment Training Programs ------------------------------------------------------------------------ Multiple Myeloma $18,950.00 Mambo for Myeloma Research Foundation ------------------------------------------------------------------------ NJ SEEDS $10,000.00 Young Scholars Program--Health Sessions ------------------------------------------------------------------------ NJ Sharing Network $5,000.00 Multicultural Outreach Foundation Initiative ------------------------------------------------------------------------ Partners in Research $25,000.00 Sanofi Biogenius Canada Canada ------------------------------------------------------------------------ PATIENT EMPOWERMENT $25,000.00 ASCO, AUA Coverage for Advanced NETWORK Prostate Cancer Patients ------------------------------------------------------------------------ Rise Against Hunger $7,500.00 Rise Against Hunger Disaster Ready Response Program ------------------------------------------------------------------------ Rutgers University $10,000.00 Vets4Warriors Foundation ------------------------------------------------------------------------ Safe + Sound Somerset $10,000.00 Residential Children's Program ------------------------------------------------------------------------ Sheltered Yoga $5,000.00 Sheltered Yoga NJ Programming ------------------------------------------------------------------------ Somerset County YMCA $6,000.00 Somerville YMCA/Annual Campaign ------------------------------------------------------------------------ Somerset Health Care $5,000.00 Quality CPR Saves Lives Foundation ------------------------------------------------------------------------ Somerset Health Care $10,000.00 El poder Foundation ------------------------------------------------------------------------ Somerset Health Care $10,000.00 El poder Foundation ------------------------------------------------------------------------ Somerset Health Care $18,560.00 1st Healthcare Conference for Foundation the LGBT Community ------------------------------------------------------------------------ Somerset Health Care $5,000.00 Quality CPR Saves Lives Foundation ------------------------------------------------------------------------ The Center For Great $10,000.00 Adult Women & their Children Expectations Inc. ------------------------------------------------------------------------ The Center For Great $10,000.00 Adult Women & their Children Expectations Inc. ------------------------------------------------------------------------ The Children's Inn at $500,000.00 Sanofi US Legacy Endowment Fund NIH, Inc. at The Children's Inn at NIH Sanofi US Legacy Endowment Fund at The Children's Inn at NIH ------------------------------------------------------------------------ The Children's Inn at $500,000.00 Sanofi US Legacy Endowment Fund NIH, Inc. at The Children's Inn at NIH ------------------------------------------------------------------------ The Children's Inn at $500,000.00 Sanofi US Legacy Endowment Fund NIH, Inc. at The Children's Inn at NIH ------------------------------------------------------------------------ THE LEUKEMIA & $18,950.00 Fiscal Year 2017 Myeloma LYMPHOMA SOCIETY Patient Education ------------------------------------------------------------------------ The Partnership for $5,000.00 General Support for PQMD Quality Medical Donations ------------------------------------------------------------------------ The Salvation Army $10,000.00 Healthy Food Pantry Program ------------------------------------------------------------------------ Trustees of University $20,000.00 Research Training in of Pennsylvania Pharmacoepidemiology ------------------------------------------------------------------------ Tyler Clementi $5,000.00 New Jersey Programs Foundation Inc ------------------------------------------------------------------------ United Way of Monroe $59,069.70 SP 2017 UW Campaign Match County ------------------------------------------------------------------------ United Way of Northern $75,000.00 Caregivers Coalition New Jersey ------------------------------------------------------------------------ Visiting Nurse $10,000.00 General Operating Association of Somerset Hills ------------------------------------------------------------------------ $3,682,101.70 ------------------------------------------------------------------------ Grand Total $16,927,350 ------------------------------------------------------------------------ Sponsorships and Charitable Donations 1st Jan 2015-31st Dec 2015 Sanofi US and its affiliate Genzyme Corporation are committed to supporting sponsorships for specific activities and initiatives of healthcare organizations and institutions, independent medical or professional societies, trade organizations and organized patient groups to improve patient care and provide information to the medical and/or patient communities. The goal of our charitable giving approach is to fund general operational support for patient/disease organizations, or program support for community-based organizations. Sanofi US and Genzyme Corporation are part of the Sanofi Group, a global pharmaceutical company. Applicant names are provided by the requestor. If applicants apply as a group for a single activity; all applicants may be not be identified above. ``Funding Amount'' is the amount that the Company funded during 2015 identified above. ``Funding Amount'' does not include funds that may have been provided by other affiliated Sanofi Company Entities (e.g., Sanofi Pasteur). Recipient Name(s) Activity Title Funding Amount Acacia In Kenya Volunteer Match $1,000.00 Acacia In Kenya Volunteer Match $1,000.00 Accelerated Cure MS Discovery: The Podcast of $102,400.00 Project the MS Discovery Forum Accelerated Cure Data Visualizations in $89,400.00 Project Multiple Sclerosis Acid Maltase Deficiency AMDA Patient Education $35,000.00 Association Inc. Programs Acid Maltase Deficiency The 2015 AMDA/IPA $20,000.00 Association Inc. International Pompe Patient and Scientific Conference Acid Maltase Deficiency AMDA Patient Education $12,000.00 Association Inc. Programs Acid Maltase Deficiency Pull for Pompe Event $3,000.00 Association Inc. ALD Connect Inc. ALD Connect Meeting $4,000.00 Alport Syndrome 2015 International Workshop $2,500.00 Foundation, Inc. on Alport Syndrome American Academy of 2015 Palatucci Advocacy $50,000.00 Neurology Institute Leadership Forum American Academy of Fellows Scholarship Program $20,000.00 Neurology Institute American Academy of Residents Scholarship Program $20,000.00 Neurology Institute American Academy of 2014-2015 Emerging Leaders $17,500.00 Neurology Institute Forum American Academy of Brain Health Fair $10,000.00 Neurology Institute American Association of 2015 Pan-American Scientific $50,000.00 Clinical Symposia on Clinical Endocrinologists Endocrinology in Latin America American Autoimmune and 50 Cents for 50 Million $5,000.00 Related Diseases Campaign AND Fight For Association Immunity Comedy Show American Chemical ACS BIOT 2015 Annual Meeting $5,000.00 Society Merck And Co Inc. American College of Summer Genetics Scholars $75,000.00 Medical Genetics Program Foundation American Physiological Experimental Biology 2015 $3,000.00 Society American Red Cross of Women Who Care, A Leadership $5,000.00 Massachusetts Breakfast American Society of ASGCT 18th Annual Meeting $5,000.00 Gene Therapy American Society of ASN Kidney Week 2015 $30,000.00 Nephrology Exhibitor Spotlight Andrew's Buddies FightSMA Annual Research $3,000.00 Corporation dba Conference 2015 FightSMA ANERA (American Near ANERA (American Near East $5,000.00 East Refugee Aid) Refugee Aid) Annual Dinner Ann & Robert H. Lurie MPS Patient and Family $2,000.00 Children's Hospital of Conference Chicago Arizona Kidney 16th Annual Southwest $6,000.00 Foundation Nephrology Conference Ashland Fire Department Community Support for Ashland $40,000.00 Association Fire Department Association Assistance Fund Inc. Multiple Sclerosis Disease $5,300,000.00 Patient Assistance Fund Program Assistance Fund Inc. Multiple Sclerosis Disease $500,000.00 Patient Assistance Fund Program Association For Annual Conference; Family $6,000.00 Glycogen Storage Assistance; The Ray Disease Beauty Bus Foundation 6th Annual Beauty Drive for $3,000.00 Patients and Caregivers Berkshire Resource 2015 Annual Gala $5,000.00 Project, Inc. Big Brothers Big Big Brothers Big Sisters $10,000.00 Sisters of Central Central Mass/Metrowest Mass Metrowest Inc. (BBBSCM) STEM Institute Biomedical Science Evening of Hope: To support $75,000.00 Careers Program underrepresented minority students/fellows interested in science Biomedical Science Hope Scholarship 2015-2016 $7,500.00 Careers Program Boston Health Care For Life Essentials Community $25,000.00 The Homeless Program Support Program Inc. Boston Plan For Boston Teacher Residency: A $15,000.00 Excellence in the High-Quality Pipeline for Public Schools Boston Public Schools' STEM Foundation Teachers Boston Private Industry 2015 Corporate Contribution's $15,000.00 Council Campaign Boston Private Industry Volunteer Match $1,000.00 Council Bottom Line Boston STEM Success Program $15,000.00 Boys and Girls Clubs of Staffing & Transportation for $25,000.00 MetroWest Increased Membership at BGCMW's Framingham Clubhouse Boys and Girls Clubs of 2015 Bids for Kids Auction & $10,000.00 MetroWest Gala Boys and Girls Clubs of Volunteer Match $4,000.00 MetroWest Boys and Girls Clubs of The 2015 Great Pumpkin Glow $5,000.00 Middlesex County Inc. Breakthrough Greater Full STEAM (Science $10,000.00 Boston Technology, Engineering, Arts, and Math) Ahead Program Cambridge Family & 2015 Circle of Friends Gala & $5,000.00 Children's Service Auction Cambridge School Volunteer Match $1,000.00 Volunteers, Inc. Camp Korey Metabolic Disorders Family $5,000.00 Weekend Can Do Multiple 2015 TAKE CHARGE Program $55,000.00 Sclerosis Can Do Multiple Can Do Program $50,000.00 Sclerosis Can Do Multiple 2015 JUMPSTART Program $50,000.00 Sclerosis Can Do Multiple Can Do 2015 Online $40,000.00 Sclerosis Programming Can Do Multiple Vertical Express for Can Do $25,000.00 Sclerosis MS Events Canavan Foundation Jewish Genetic Disease $4,500.00 Leadership Database Expansion Project Case Management Society CMSA 25th Annual Conference & $14,000.00 of America Expo Case Management Society CMSA 25th Annual Conference & $4,800.00 of America Expo (Booth) Case Management Society Case Management Society of $1,000.00 of New England New England's 26th Annual Conference and Exhibitor Expo CASSS--An International CMC Strategy Forums $2,500.00 Separation Science Society Charcot-Marie-Tooth CMTA's Boston Patient/Family $5,000.00 Association Conference Charcot-Marie-Tooth CMTA's Boston Patient/Family $2,000.00 Association Conference Children's Hospital Global Pediatric Innovation $20,000.00 Boston Summit + Awards 2015 Children's Hospital La Gala de Milagros para $5,000.00 Corporation Ninos Church Hillers Inc. Volunteer Match $1,000.00 City Sprouts, Inc. After School Ecology Clubs $7,000.00 Colon Cancer Coalition Volunteer Match $2,000.00 Community Boating, Inc. Universal Access Program $15,000.00 2015--Patient Assistance Program Community Farms Fresh Food Access Program $12,000.00 Outreach Community Rowing, Inc. Let's Row Boston $15,000.00 Community Servings, Pie in the Sky $10,000.00 Inc. Consortium of Multiple 29th Annual Meeting of the $52,000.00 Sclerosis Centers Consortium of Multiple Sclerosis Centers Breakfast Council on Renal Patient Empowerment Workshop $1,000.00 Nutrition of Western PA Courage to Make a Courage: Living life without $1,000.00 Difference Inc. limit patient videos Cradles to Crayons Inc. Ready for School and Backpack- $20,000.00 a-Thon Cystic Fibrosis Uncork the Cure Event $10,000.00 Foundation DEAF, Inc.-- Deaf-Accessible Medical Case $10,000.00 Developmental Management and Health Evaluation and Education Adjustment Facilities, Inc. Deliver The Dream Inc. Community Champions Awards $2,500.00 Department of Neurology Shop to Stop Multiple $10,000.00 Multiple Sclerosis Sclerosis Center of Excellence Dimock Community Health Building the Road to $150,000.00 Center Recovery--Expanding and Renovating Acute Treatment Services DISARM Education FUND, Combating Rare Diseases and $20,000.00 INC. Raising Awareness in the Developing World East End House Inc. Generating and Evaluating New $20,000.00 Adventures in Science After School (GENASAS) East End House Inc. Volunteer Match $2,000.00 Emory Genetics LSDC Patient Meetings $27,390.00 Laboratory Engineering Conferences Integrated Continuous $10,000.00 International Biomanufacturing II Conference EveryLife Foundation Rare Voice Awards Gala $20,000.00 for Rare Diseases EveryLife Foundation EveryLife Foundation Annual $10,000.00 for Rare Diseases Rare Disease Scientific Workshop: Patient Engagement in the Clinical Development Process Fabry Support & FSIG Expert Fabry Conference $50,000.00 Information Group 2015 Fabry Support & FSIG Patient Assistance Fund $40,000.00 Information Group Fabry Support & FSIG Patient Assistance Fund $40,000.00 Information Group Fabry Support & Rapid Assistance Funds-- $30,000.00 Information Group Patient Assistance Program Fabry Support & FSIG Newsletter $12,000.00 Information Group Fabry Support & 2015 FSIG Fabry Fun Run/Walk $1,500.00 Information Group & FSIG Fabry Get Together Meeting Family Promise Keep the Promise: An evening $2,500.00 Metrowest Inc. of food tasting to benefit families that are homeless Foundation of the 2016 CMSC Annual Meeting-- $414,000.00 Consortium of Multiple Celebrating 30 Years of MS Sclerosis Centers Care Foundation of the FCMSC 2015-2016 Pilot $44,000.00 Consortium of Multiple Research Grant Award in Sclerosis Centers Multiple Sclerosis Foundation of the NARCOMS Now Patient Quarterly $33,358.00 Consortium of Multiple Magazine Sclerosis Centers Foundation of the 2015-2016 FCMSC Medical $22,000.00 Consortium of Multiple Resident Annual Meeting Sclerosis Centers Scientific Scholarships Foundation of the 2015-2016 Workforce of the $22,000.00 Consortium of Multiple Future: Medical Student Sclerosis Centers Scholarships Framingham Townwide PTO Volunteer Match $1,000.00 Council Franciscan Children's Adaptive Sports Program for $10,000.00 Hospital and Children with Disabilities Rehabilitation Center Friends of Hopkinton Community Support for general $4,000.00 SPEAC operating Friends of Resiliency Academic Support component of $10,000.00 for Life Inc. Resiliency for Life (RFL) Friends of Resiliency Volunteer Match $1,000.00 for Life Inc. Friends of the Community Support for Friends $16,000.00 Hopkinton Seniors group to raise funds for nutrition programs FSH Society, Inc. FSH Society $2,000.00 Facioscapulohumeral Muscular Dystrophy [FSHD] 2015 International Research Consortium & Research Planning Meetings Fundacion de Esclerosis MS Community Educational $20,000.00 Multiple de Puerto Conferences Rico Fundacion de Esclerosis Abrazarte a la vida Patient $2,500.00 Multiple de Puerto Fundraising Event Rico Gateway Area Chapter Community Walk MS 2015 $5,000.00 Gateway Area Chapter Women on the Move Luncheon $2,500.00 2015 Generation Citizen Inc. Generation Citizen Spring $5,000.00 2015 Civics Day Georgia Chapter of the Non-AAP industry/foundation $3,500.00 American Academy of symposium Pediatrics Girl Scouts of Eastern Girls Building Self-esteem $10,000.00 Massachusetts Inc. Global Genes 4th Annual RARE Tribute to $25,000.00 Champions Event Global Genes Global Genes RARE Patient $25,000.00 Advocacy Summit Global Genes Global Genes Corporate $15,000.00 Alliance Program Global Genes Give RARE Disease Giving Day $10,000.00 Global Genes Pixar's The Good Dinosaur-- $10,000.00 Exclusive Screening & Fundraiser Global Genes Tribute to Champions-- $7,460.00 Expression of Hope Art Exhibit Global Genes RARE Toolkit & Educational $5,000.00 Podcast Programs Gordon Research Lysosomal Diseases Gordon $5,000.00 Conferences Research Conference and Gordon Research Seminar Gordon Research 2015 CAG Repeat Disorders $2,000.00 Conferences Gordon Research Conference Greater Boston Chamber Chamber's 2015 Annual Meeting $10,000.00 of Commerce Habitat For Humanity Holliston Build Project $15,000.00 Metrowest--Greater Worcester Inc. Habitat For Humanity Volunteer Match $2,000.00 Metrowest--Greater Worcester Inc. Health Care For All Ethnic Media and Grassroots $10,000.00 Inc. Outreach to Improve Health Coverage Access in Framingham Health Technology HTAI Annual Meeting 2015 $20,000.00 Assessment International Hearts & Noses Hospital Ongoing Hospital Clown Visits $15,000.00 Clown Troupe Inc. to Ill and Disabled Children in Greater Boston Holy Name Health Care 18th Annual Spring Fashion $15,000.00 Foundation Inc. Fling for MS Horizons for Homeless 17th Annual Women's Breakfast $3,500.00 Children Huntington Study Group HSG 2015: Building Our Future $1,500.00 Ltd. Huntington's Disease Huntington's Disease Society $2,500.00 Society of America of America 30th Annual Convention Icahn School of 13th Annual Gala in Support $25,000.00 Medicine at Mount of the Corinne Goldsmith Sinai Dickinson Center for Multiple Sclerosis at Mount Sinai Icahn School of 13th Annual Gala in Support $12,000.00 Medicine at Mount of the Corinne Goldsmith Sinai Dickinson Center for Multiple Sclerosis at Mount Sinai International 2015 MS Perspectives $75,000.00 Organization of Publication Multiple Sclerosis Nurses International 2015 Annual Meeting IOMSN $30,000.00 Organization of Dinner Multiple Sclerosis Nurses International Society Glycoproteinoses: Fourth $5,000.00 For Mannosidosis & International Conference on Related Disease Inc. Advances in Pathogenesis and Therapy International Society 31st International Conference $2,000.00 For on Pharmacoepidemiology Pharmacoepidemiology International Society ISN Forefronts $3,500.00 of Nephrology ``Immunomodulation of Cardio- Renal Function--A focus on cardio-renal pathophysiology and immunity'' (Oct 22-25, 2015, Shenzhen, China) Italian Home For City Lights Gala $5,000.00 Children Inc. Japan Society of Boston 2015 Japan Society of Boston $5,000.00 Annual Dinner Jewish Federation of Expanding Footprint of Jewish $10,000.00 southern New Jersey Genetic Disease Awareness in South Jersey Jewish Genetic Disease Jewish Genetic Disease $5,000.00 Consortium (JGDC) Consortium Screening Awareness Program Jewish Genetic Diseases PHOENIX--Our Heritage and our $980.00 Center of Greater Health--Ashkenazi Jewish Phoenix Genetics Disease and the Founder Effect Jewish Genetic Diseases TUCSON--Our Heritage and our $950.00 Center of Greater Health--Ashkenazi Jewish Phoenix Genetic Disease and the Founder Effect Joseph M. Smith JMSCHS's Prenatal Program $15,000.00 Community Health Center, Inc. Kidney Foundation of 24th Annual Wine Affair Event $1,000.00 Northwest Ohio for Disease Awareness Kidney Foundation of Kilometers for Kidneys $500.00 Northwest Ohio Light of Life Light of Life Foundation 2015 $25,000.00 Foundation Patient Support Activities Light of Life Light of Life Foundation $20,000.00 Foundation Patient Awareness Program Light of Life Light of Life Foundation $1,000.00 Foundation Night of Comedy Fundraiser Little Brothers/Friends Medical Escort/Transport and $7,500.00 of the Elderly Prescription Escort Patient Assistance Program Little Miss Hannah Little Miss Hannah Foundation $8,000.00 Foundation General Operating Support Little Miss Hannah Little Miss Hannah's Rainbows $1,000.00 Foundation in the Wind Festival Lysosomal and Rare Towards a patient-centered $10,000.00 Disorders Research and disease registry; Connecting Treatment Center Inc. the patches for Gaucher Disease March of Dimes March for Babies $15,000.00 March of Dimes Black Ties for Babies Gala $10,000.00 March of Dimes Volunteer Match $2,000.00 March of Dimes Volunteer Match $1,000.00 March of Dimes Volunteer Match $1,000.00 Margaret Fuller Scholarships for Port/Area IV $15,000.00 Neighborhood House Youth to Attend Summer Camp at Margaret Fuller House Mass Insight Education College Success Program $15,000.00 and Research Institute Inc. Massachusetts Bay STEM Mentor Program $26,500.00 Community College Foundation Massachusetts Patient Advocacy Summit--Live $10,000.00 Biotechnology Council & Breathe: Building a Patient Centered Biotech Massachusetts BioTeach Life Sciences $50,000.00 Biotechnology Student Program Education Foundation Inc. Massachusetts Institute Cambridge Science Festival $5,000.00 of Technology Massachusetts Outdoor DFW Plymouth Red-bellied $5,000.00 Heritage Foundation Cooter Head-starting Program Inc. Massachusetts Outdoor Volunteer Match $1,000.00 Heritage Foundation Inc. Massachusetts State Massachusetts State Science & $50,000.00 Science and Engineering Fair Engineering Fair, Inc. Mercy Foundation Mercy Multiple Sclerosis (MS) $20,000.00 Achievement Center Wellness Programs Metrowest Free Medical Chronic Disease Patient $10,000.00 Program Inc. Assistance Program Mid America MS The Race to Nowhere 2015 $5,000.00 Achievement Center Mid America MS The Race to Nowhere 2015 $2,500.00 Achievement Center Mid America MS Eat Bid Laugh Event $2,500.00 Achievement Center benefiting the Mid-America Multiple Sclerosis Achievement Center (MSAC) in Kansas City Milwaukee Synagogue for Gaucher Disease Education $5,000.00 Russian Jews Program MLD Foundation RUSP Roundtable $4,000.00 MS Cure Fund Women Thriving With MS $125,000.00 MS Cure Fund Risks & Benefits Program $103,700.00 MS Cure Fund Resource Information Database $12,360.00 Conversion and Website Integration MS Cure Fund MS Cure Newsletter $10,000.00 MS Cure Fund Lifestyle Management Programs $8,250.00 Fall 2015 MS Hope for a Cure Inc. 2015 MS Cycle for a Cure--A $5,000.00 Ride for Research (6 event sites) MS Views and News Inc. 2015--MS Symposium SERIES-- $64,491.00 ``The Neurological Aspects of MS'' MS Views and News Inc. Empowering MS Communities in $46,000.00 America's Heartland series-- 2 MS Views and News Inc. BRING IT ON!--``Everything $27,835.00 You Want to Know about MS'' a Q&A program MS Views and News Inc. Empowering MS Communities in $22,000.00 America's Hearthland series MS Views and News Inc. Women's Health Issues with $16,924.75 Multiple Sclerosis MS Views and News Inc. New and Emerging Therapies $15,925.00 plus Invisible Symptoms of MS MS Views and News Inc. New and Emerging Treatment $14,750.00 Options plus Invisible Symptoms of MS--Chicago MS Views and News Inc. BRING IT ON!--Everything you $12,295.00 want to Know about MS--Q&A MS Views and News Inc. Women's Health with Multiple $9,582.00 Sclerosis MS Views and News Inc. Men's Health Issues with $9,178.50 Multiple Sclerosis MS Views and News Inc. 2015 Renewal of Annual $7,900.00 Display Sponsorship MS Views and News Inc. MS Views and News--5th Annual $3,000.00 Bowlathon Fundraiser to Benefit MS Education and Stem Cell Research MSWorld, Inc. 2015 MSWorld Conference $20,000.00 Coverage MSWorld, Inc. 2015 MSWorld ``Wellness $20,000.00 Unleashed Program'' Multiple Sclerosis Crossfire: The Science and $436,320.00 Association of America Emotion of Risk Multiple Sclerosis MSAA MRI Patient Assistance $350,000.00 Association of America Fund Multiple Sclerosis Hot Topics in Multiple $217,941.00 Association of America Sclerosis: An Interactive Series of MS Patient Education Programs Multiple Sclerosis Swim for MS In Person Program $58,985.00 Association of America Pilot Series Multiple Sclerosis MSAA's 2015 Improving Lives $15,000.00 Association of America Benefit Multiple Sclerosis MS Festival Program $10,000.00 Center of Georgia Multiple Sclerosis Health, Hope & Hops Program $7,000.00 Center of Georgia Multiple Sclerosis Foundation's Assistive $50,000.00 Foundation Technology Program Multiple Sclerosis Support Group News quarterly $27,300.00 Foundation informational newsletter Multiple Sclerosis African Americans with MS-- $20,000.00 Foundation The Medical, Cultural and Psychological Differences Multiple Sclerosis Resource Website $117,367.00 International Communications Support Federation Foundation Inc. Multiple Sclerosis Middle East Patient Awareness $78,245.00 International Program Federation Foundation Inc. Multiple Sclerosis Arab Region Patient Awareness $60,117.00 International Program Federation Foundation Inc. Multiple Sclerosis World MS Day 2015 Campaign $46,947.00 International Federation Foundation Inc. Multiple Sclerosis Latin America Resource $41,950.00 International Analysis Project Federation Foundation Inc. Multiple Sclerosis Global Patient Awareness $39,122.00 International Program Federation Foundation Inc. Multiple Sclerosis MSQLP's 9th Annual Walk 'n $1,500.00 Quality of Life Roll Fundraiser Project Corporation Multiple Sclerosis 2015 Mission Steps Wak & MS $8,000.00 Resources of Central Awareness Day New York, Inc. Muscular Dystrophy Muscle Walk 2015 $1,000.00 Association--Lake Mary, FL Muscular Dystrophy 2015 MDA Muscle Summit $8,000.00 Association--Alameda, CA Muscular Dystrophy MDA Newsletter $2,000.00 Association--Albany, NY Muscular Dystrophy 2015 MDA Research Seminar $2,000.00 Association--Albany, NY Muscular Dystrophy New Mexico MDA Muscle Walk $1,000.00 Association--Albuquerq ue, NM Muscular Dystrophy 2015 MDA Muscle Summit $8,000.00 Association--Allentown , PA Muscular Dystrophy Muscle Walk Greater Lehigh $1,000.00 Association--Allentown Valley , PA Muscular Dystrophy 17th Annual Black and Blue $5,000.00 Association--Ark Ball Valley, Richmond, VA Muscular Dystrophy Muscle Walk Greater Fort $1,000.00 Association--Ark Wayne Valley, Richmond, VA Muscular Dystrophy Muscle Walk Ft Myers, FL $1,000.00 Association--Ark Valley, Richmond, VA Muscular Dystrophy Muscle Walk Pittsburgh $1,000.00 Association--Ark Valley, Richmond, VA Muscular Dystrophy Muscle Walk Springfield, MO $1,000.00 Association--Ark Valley, Richmond, VA Muscular Dystrophy Muscle Walk Richmond, VA $1,000.00 Association--Ark Valley, Richmond, VA Muscular Dystrophy Muscle Walk Central Texas $1,000.00 Association--Austin, TX Muscular Dystrophy 2015 Muscular Dystrophy $1,000.00 Association--Billings, Summer Camp of Montana MT Muscular Dystrophy Muscle Walk Montana $1,000.00 Association--Billings, MT Muscular Dystrophy MDA Health Patient Care $1,000.00 Association - Services Program Birmingham, AL Muscular Dystrophy MDA Idaho Summer Camp $1,000.00 Association--Boise, ID Muscular Dystrophy MDA Superhero Muscle Walk and $1,000.00 Association--Boise, ID 5k Fun Run Muscular Dystrophy Muscle Walk of Chattanooga $2,500.00 Association--Brentwood , TN Muscular Dystrophy Muscle Walk of Nashville $1,000.00 Association--Brentwood , TN Muscular Dystrophy 2015 Nashville Muscle Team $1,000.00 Association--Brentwood Gala , TN Muscular Dystrophy Muscle Walk of Nashville $1,000.00 Association--Brentwood , TN Muscular Dystrophy Muscle Walk of Greater $1,000.00 Association--Brookfiel Milwaukee d, WI Muscular Dystrophy Muscle Walk of Greater $1,000.00 Association--Brookfiel Madison d, WI Muscular Dystrophy Muscle Walk 2015 $1,000.00 Association--Broomall, PA Muscular Dystrophy Muscle Walk Quad Cities $1,000.00 Association--Cedar Rapids, IA Muscular Dystrophy Muscle Walk Des Moines $1,000.00 Association--Cedar Rapids, IA Muscular Dystrophy Muscle Walk Iowa City $1,000.00 Association--Cedar Rapids, IA Muscular Dystrophy Muscle Walk Iowa City $1,000.00 Association--Cedar Rapids, IA Muscular Dystrophy Muscle Walk Waterloo $1,000.00 Association--Cedar Rapids, IA Muscular Dystrophy Muscle Walk Des Moines $1,000.00 Association--Cedar Rapids, IA Muscular Dystrophy Mucscle Walk Morgantown $1,000.00 Association--Charlesto n, WV Muscular Dystrophy Muscle Walk 2015 $1,000.00 Association--Charlotte , NC Muscular Dystrophy MDA--LGMD Genetic Testing $700,000.00 Association--Chicago, Program IL Muscular Dystrophy MDA Pompe Testing Program $60,000.00 Association--Chicago, IL Muscular Dystrophy 2015 Muscle Summit $8,000.00 Association--Chicago, IL Muscular Dystrophy MDA Illinois Muscle Summit $8,000.00 Association--Chicago, IL Muscular Dystrophy Muscular Dystrophy $2,000.00 Association--Chicago, Association, Third Quarter IL Newsletter Muscular Dystrophy Muscle Walk 2015 $1,000.00 Association--Chicago, IL Muscular Dystrophy MDA-ALS Muscle Walk $1,000.00 Association--Chicago, IL Muscular Dystrophy 2015 Southern Ohio Muscular $1,000.00 Association--Cincinnat Dystrophy Association Summer i, OH Camp Muscular Dystrophy Muscle Walk of Greater $1,000.00 Association--Cincinnat Cincinnati i, OH Muscular Dystrophy Muscle Walk of Greater $1,000.00 Association--Cleveland Cleveland , OH Muscular Dystrophy MDA Winter Newsletter $2,500.00 Association--Columbia, SC Muscular Dystrophy Road Map to Independence for $2,000.00 Association--Columbia, Young Adults Resource SC Program Muscular Dystrophy MDA Fall Newsletter $2,000.00 Association--Columbia, SC Muscular Dystrophy Muscle Walk $1,000.00 Association--Columbia, SC Muscular Dystrophy Muscle Walk of Denver $1,000.00 Association--Denver, CO Muscular Dystrophy Muscle Walk of Chicagoland & $2,000.00 Association--Downers Muscle Walk of Rockford Grove, IL Muscular Dystrophy Muscle Walk 2015 $1,000.00 Association--El Paso, TX Muscular Dystrophy Muscle Walk Greater Mishawaka $1,000.00 Association--Fort Wayne, IN Muscular Dystrophy Muscle Walk of Greater $1,000.00 Association--Fort Mishawaka Wayne, IN Muscular Dystrophy Muscle Walk Western Colorado $1,000.00 Association--Grand Junction, CO Muscular Dystrophy Partners in Progress: an MDA $5,000.00 Association--Green Muscle Symposium Bay, WI Muscular Dystrophy Muscle Walk of Green Bay $1,000.00 Association--Green Bay, WI Muscular Dystrophy Muscle Walk 2015 $1,000.00 Association--Greenvill e, SC Muscular Dystrophy Limb-Girdle Muscular $10,000.00 Association--Harrisbur Dystrophy Education Program, g, PA First Quarter, 2015 Muscular Dystrophy 2015 Central PA MDA Muscle $8,000.00 Association--Harrisbur Summit g, PA Muscular Dystrophy Muscle Walk Central PA $1,000.00 Association--Harrisbur g, PA Muscular Dystrophy Muscle Walk Hawaii $1,500.00 Association--Honolulu, HI Muscular Dystrophy Muscle Walk Houston $1,000.00 Association--Houston, TX Muscular Dystrophy Patient and Family Healthcare $2,000.00 Association--Jacksonvi Newsletter lle, FL Muscular Dystrophy Muscle Walk 2015 $1,000.00 Association--Knoxville , TN Muscular Dystrophy Muscle Walk $1,000.00 Association--Knoxville , TN Muscular Dystrophy Family Engagement Events $1,000.00 Association--Knoxville , TN Muscular Dystrophy Muscle Walk $1,000.00 Association--Las Vegas, NV Muscular Dystrophy Muscle Walk of Little Rock $1,000.00 Association--Little Rock, AR Muscular Dystrophy MDA Summer Camp $5,000.00 Association--Los Angeles, CA Muscular Dystrophy Muscle Walk Louisville $1,000.00 Association--Louisvill e, KY Muscular Dystrophy Muscle Walk $1,000.00 Association--Louisvill e, KY Muscular Dystrophy MDA Conference $1,500.00 Association--Mancheste r, NH Muscular Dystrophy Muscle Walk St Louis $1,000.00 Association--Maryland Heights, MO Muscular Dystrophy 2015 Central New Jersey MDA $8,000.00 Association--Maywood, Muscle Summit NJ Muscular Dystrophy 2nd Quarter/4th Quarter Print $2,000.00 Association--Maywood, Newsletters 2015 NJ Muscular Dystrophy Muscle Walk $1,000.00 Association--Memphis, TN Muscular Dystrophy Muscle Walk 2015 $1,000.00 Association--Metairie, LA Muscular Dystrophy Muscle Walk Baton Rouge $1,000.00 Association--Metairie, LA Muscular Dystrophy MDA South Alabama Chapter $2,000.00 Association--Montgomer Quarterly Family Newsletter y, AL Muscular Dystrophy Muscular Dystrophy $2,000.00 Association--New Association 2015 2nd Quarter Haven, CT Newsletter Muscular Dystrophy Muscle Walk Metro NY $1,000.00 Association--New York, NY Muscular Dystrophy Muscular Dystrophy $2,000.00 Association--North Association 1st Quarter 2015 Haven, CT Newsletter Muscular Dystrophy 18th Annual MDA Black and $2,000.00 Association--North Blue Ball Haven, CT Muscular Dystrophy Muscular Dystrophy $1,500.00 Association--North Association 2015 3rd Quarter Haven, CT Newsletter Muscular Dystrophy 2015 Mohegan Sun Southern New $1,000.00 Association--North England MDA Muscle Walk Haven, CT Muscular Dystrophy Muscle Walk of Greater $1,000.00 Association--Okemos, Lansing Area MI Muscular Dystrophy Muscle Walk $1,000.00 Association--Okemos, MI Muscular Dystrophy Muscle Walk 2015 $1,000.00 Association--Omaha, NE Muscular Dystrophy Muscle Walk Medford $1,000.00 Association--Portland, OR Muscular Dystrophy Muscle Walk $1,000.00 Association--Portland, OR Muscular Dystrophy Muscle Walk Raleigh $1,000.00 Association--Raleigh, NC Muscular Dystrophy Muscle Walk 2015 $1,000.00 Association--Reston, VA Muscular Dystrophy Fall 2015 Newsletter $1,200.00 Association--Rochester , NY Muscular Dystrophy Muscle Walk 2015 $1,000.00 Association--Salt Lake City, UT Muscular Dystrophy Muscle Walk Salt Lake City $1,000.00 Association--Salt Lake City, UT Muscular Dystrophy Muscle Walk San Antonio & 5K $1,000.00 Association--San Fun Run Antonio, TX Muscular Dystrophy Muscle Walk Twin Cities $1,500.00 Association--Shrevepor t, LA Muscular Dystrophy Patient Newsletter $1,500.00 Association--Southfiel d, MI Muscular Dystrophy MDA Summer Camp 2015 $1,000.00 Association--Spokane, WA Muscular Dystrophy Muscle Walk Spokane $1,000.00 Association--Spokane, WA Muscular Dystrophy MDA Summer Camp 2015 $1,000.00 Association--St Petersburg, FL Muscular Dystrophy MDA Summer Camp 2015 $1,000.00 Association--St Petersburg, FL Muscular Dystrophy Muscle Walk Tampa Bay $1,000.00 Association--St Petersburg, FL Muscular Dystrophy MDA Muscle Walk--Exhibit $1,000.00 Association--Tempe, AZ Booth for Patient Education Muscular Dystrophy MDA Muscle Walk Tucson-- $1,000.00 Association--Tempe, AZ Exhibit Booth for Patient Education Muscular Dystrophy Muscle Walk of Baltimore $1,000.00 Association--Towson, MD Muscular Dystrophy Muscle Walk Ark-La-Tex $1,000.00 Association--Tucson, AZ Muscular Dystrophy Muscle Walk Central New $1,000.00 Association--Tucson, Jersey AZ Muscular Dystrophy MDA 4th Quarter Newsletter $2,000.00 Association--Warwick, RI Muscular Dystrophy Newsletter-CAMP $2,000.00 Association--Westborou gh, MA Muscular Dystrophy Volunteer Match $1,000.00 Association--Westborou gh, MA Muscular Dystrophy Quarterly Newsletter $3,000.00 Association--Westbrook , ME Muscular Dystrophy Pompe Support Dinner $2,000.00 Association--Westbrook , ME Muscular Dystrophy Pompe Awareness and Education $1,500.00 Association--Westbrook Day , ME Muscular Dystrophy Pompe Awareness and $1,000.00 Association--Westbrook EducationDay , ME Muscular Dystrophy Limb-Girdle Support Group $1,000.00 Association--Westbrook , ME Muscular Dystrophy Muscle Walk Maine $1,000.00 Association--Westbrook , ME Muscular Dystrophy 2015 MDA Muscle Walk and $2,000.00 Association--Wilmingto Educational Symposium n, NC Muscular Dystrophy Muscle Walk of Greenville and $1,500.00 Association--Wilmingto Patient Educational n, NC Symposium Muscular Dystrophy Muscle Walk of Central Ohio $1,000.00 Association--Worthingt on, OH Muscular Dystrophy Muscle Walk $1,000.00 Association--Worthingt on, OH Muscular Dystrophy Muscle Walk $1,000.00 Association--Westborou gh, MA Museum of Science Genzyme/Museum of Science $66,980.00 Teacher Sabbatical Program 2014 Museum of Science The Science Behind the Stars $10,000.00 Event National Fabry Disease 2015 NFDF Education and $45,000.00 Foundation Community Patient Assistance Program National Fabry Disease 2015 NFDF Core Patient $40,000.00 Foundation Assistance Program National Fabry Disease 2015 NFDF Core Patient $40,000.00 Foundation Assistance Program National Fabry Disease 2015 Fabry Family Camp and $25,000.00 Foundation Annual Educational Conference National Fabry Disease 2015 Fabry Family Camp and $25,000.00 Foundation Annual Educational Conference National Fabry Disease 2015 Fabry Family Camp and $25,000.00 Foundation Annual Educational Conference National Fabry Disease 2015 Fabry Educational $14,000.00 Foundation Meetings National Fabry Disease 2015 Fabry Emergency $10,000.00 Foundation Assistance and Ancillary Expense Support National Fabry Disease 2015 Fabry Emergency $10,000.00 Foundation Assistance and Ancillary Expense Support National Fabry Disease 2015 Family Patient $5,000.00 Foundation Assistance Program National Fabry Disease 2015 Family Patient $5,000.00 Foundation Assistance Program National Family RareCaregivers.org: Caring $10,000.00 Caregivers Association for Rare Disease Caregivers DBA Caregiver Action Network National Family Creating the Voice: A $5,000.00 Caregivers Association Celebration of Family DBA Caregiver Action Caregiving Event Network National Gaucher CARE Program--Patient $1,250,000.00 Foundation Assistance Program National Gaucher NGF Education, Awareness and $400,000.00 Foundation Resources Program for Patients National Gaucher 2015 National Gaucher $25,000.00 Foundation Conference National Kidney Louisville Kidney Walk $1,000.00 Foundation Inc. National Kidney Great Chefs of the West Gala $200.00 Foundation Inc. National Kidney Evansville Kidney Walk $500.00 Foundation of Indiana National Kidney Northwest Kidney Walk $500.00 Foundation of Indiana National Kidney Northeast Indiana Kidney Walk $500.00 Foundation of Indiana National Kidney 2015 Mardi Gras Kidney Ball $1,000.00 Foundation of Michigan National MPS Society National MPS Society 29th $20,000.00 Annual Family Conference National MPS Society National MPS Society 29th $15,000.00 Annual Family Conference National MPS Society National MPS Society 5K Walk/ $10,000.00 Run National Multiple Southern New York Chapter's $100,000.00 Sclerosis Society--New Walk MS 2015 York, NY National Multiple Chapter Women Against MS $1,000.00 Sclerosis Society-- Luncheon Arizona National Multiple Spring Fling/Fall Ball $10,000.00 Sclerosis Society--New Socialization Programs for York, NY People with MS National Multiple Moving Forward: An $3,000.00 Sclerosis Society--New Educational Program for York, NY Those Newly Diagnosed with Multiple Sclerosis National Multiple The National Multiple $2,500.00 Sclerosis Society-- Sclerosis Society, Alabama-- Alabama-Mississippi Mississippi Chapter's MS Chapter Dinner of Champions National Multiple MS Symposium $1,000.00 Sclerosis Society-- Alabama-Mississippi Chapter National Multiple Arizona Chapter's Walk MS $10,000.00 Sclerosis Society-- 2015 Arizona Chapter National Multiple Women Against MS Luncheon-- $2,500.00 Sclerosis Society-- Patient Wellness Program Brentwood, TN National Multiple Newly Diagnosed with MS $1,150.00 Sclerosis Society-- Meeting Brentwood, TN National Multiple Women's Day Out: Health, $450.00 Sclerosis Society-- Beauty, Wellness and MS Brentwood, TN National Multiple Central Virginia Chapter's $15,000.00 Sclerosis Society-- Walk MS 2015 Central Virginia Chapter National Multiple Women on the Move Luncheon $2,500.00 Sclerosis Society-- Central Virginia Chapter National Multiple Mind and Body Wellness $1,000.00 Sclerosis Society-- Educational Symposium Central Virginia Chapter National Multiple Colorado-Wyoming Chapter's $15,000.00 Sclerosis Society-- Walk MS 2015 Colorado-Wyoming Chapter National Multiple I Ride with MS at Bike MS $10,000.00 Sclerosis Society-- Colorado Event Colorado-Wyoming Chapter National Multiple 2015 SH & Patient Support $8,610.00 Sclerosis Society-- Groups Colorado-Wyoming Chapter National Multiple Optimal Health with MS-- $8,350.00 Sclerosis Society-- Integrating Lifestyle, Colorado-Wyoming Alternative & Conventional Chapter Medicine National Multiple Fitness as a Lifestyle 2015-- $4,710.00 Sclerosis Society-- Patient Wellness Program Colorado-Wyoming Chapter National Multiple National MS Society $25,000.00 Sclerosis Society-- Scholarship Program Denver, CO National Multiple Navigator Patient Resource $15,000.00 Sclerosis Society-- Program Gateway Area Chapter MS National Multiple Walk MS 2015 $5,000.00 Sclerosis Society-- Gateway Area Chapter National Multiple Walk MS $50,000.00 Sclerosis Society-- Greater Illinois Chapter National Multiple MuckFest MS Chicago Race $15,000.00 Sclerosis Society-- Greater Illinois Chapter National Multiple 7th Annual Women on the Move $7,000.00 Sclerosis Society-- Luncheon Greater Illinois Chapter National Multiple Walk MS Boston $25,000.00 Sclerosis Society-- Greater New England Chapter National Multiple Muckfest MS Boston $25,000.00 Sclerosis Society-- Greater New England Chapter National Multiple Bike MS Ride the Vineyard $10,000.00 Sclerosis Society-- Greater New England Chapter National Multiple National MS Walks Worcester $2,000.00 Sclerosis Society-- and Boston Greater New England Chapter National Multiple Maine Living Well with MS $1,500.00 Sclerosis Society-- Program Greater New England Chapter National Multiple Vermont Living Well with MS $1,250.00 Sclerosis Society-- Conference Greater New England Chapter National Multiple Hidden Symptoms of MS $1,250.00 Sclerosis Society-- Conference Greater New England Chapter National Multiple New Hampshire Spring $1,250.00 Sclerosis Society-- Education Conference Greater New England Chapter National Multiple Rhode Island Living Well with $1,250.00 Sclerosis Society-- MS Spring Conference Greater New England Chapter National Multiple Connecticut Walk MS 2015 $2,500.00 Sclerosis Society-- Hartford, CT National Multiple National MS Society South $20,000.00 Sclerosis Society-- Central Region BP 150 Bike Houston, TX Race Event National Multiple North Texas Walk MS 2015 $18,000.00 Sclerosis Society-- Houston, TX National Multiple Tulsa & Central, OK Walk MS $10,000.00 Sclerosis Society-- 2015 Houston, TX National Multiple San Antonio MS Walk 2015 $10,000.00 Sclerosis Society-- Houston, TX National Multiple 2015 Oklahoma Leadership $10,000.00 Sclerosis Society-- Events Houston, TX National Multiple Lydia Emily Project $10,000.00 Sclerosis Society-- supporting BP 150 Bike Race Houston, TX Event National Multiple North Texas Bike MS 2015 $7,500.00 Sclerosis Society-- Houston, TX National Multiple On The Move Luncheon program $5,000.00 Sclerosis Society-- to raise funds and awareness Houston, TX for Multiple Sclerosis National Multiple I Ride With MS Oklahoma Bike $5,000.00 Sclerosis Society-- Event Houston, TX National Multiple Louisiana--New Orleans, $3,500.00 Sclerosis Society-- Shreveport, and Baton Rouge Houston, TX Walk MS 2015 National Multiple Bike MS Event--Midland $3,000.00 Sclerosis Society-- Houston, TX National Multiple On The Move Luncheon Baton $2,500.00 Sclerosis Society-- Rouge Houston, TX National Multiple Ohio Buckeye Chapter's Walk $5,000.00 Sclerosis Society-- MS 2015 Independence, OH National Multiple North Florida Walk MS 2015 $7,500.00 Sclerosis Society-- Jacksonville, FL National Multiple MS On the Move Luncheon $2,500.00 Sclerosis Society-- Jacksonville, FL National Multiple MS On the Move Luncheon $1,000.00 Sclerosis Society-- Jacksonville, FL National Multiple MS Awareness Mural $10,000.00 Sclerosis Society-- Kentucky-Southeast Indiana Chapter National Multiple Walk MS Kentucky $10,000.00 Sclerosis Society-- Kentucky-Southeast Indiana Chapter National Multiple Moving Mountains For MS: 2015 $7,500.00 Sclerosis Society-- Family Weekend Retreat Kentucky-Southeast Indiana Chapter National Multiple Crystal Boots & Silver Spurs $5,000.00 Sclerosis Society-- Fundraising Event Kentucky-Southeast Indiana Chapter National Multiple Best of Louisville 2015 $3,000.00 Sclerosis Society-- Patient Resources Event Kentucky-Southeast Indiana Chapter National Multiple Women on the Move--Patient $1,000.00 Sclerosis Society-- Awareness Program Kentucky-Southeast Indiana Chapter National Multiple Long Island Walk MS 2015 $5,000.00 Sclerosis Society-- Long Island Chapter National Multiple 10th Annual Spring into $3,000.00 Sclerosis Society-- Awareness Luncheon Long Island Chapter National Multiple Southern California & Nevada $25,000.00 Sclerosis Society--Los Chapter's Walk MS 2015 Angeles, CA National Multiple 40th Annual Dinner of $5,000.00 Sclerosis Society--Los Champions Angeles, CA National Multiple Program on Fueling Impact in $4,000.00 Sclerosis Society--Los MS Research Angeles, CA National Multiple Lydia Emily ``Make Your Mark $2,500.00 Sclerosis Society--Los on MS'' Mural Project that Angeles, CA will provide hope to the local MS community and greatly increase public awareness of MS National Multiple Dinner of Champions Northern $2,500.00 Sclerosis Society--Los Nevada Angeles, CA National Multiple Maryland Walk MS 2015 $7,500.00 Sclerosis Society-- Maryland Chapter National Multiple Walk MS 2015 $5,000.00 Sclerosis Society--MI Chapter National Multiple The 37th Annual Ambassadors $25,000.00 Sclerosis Society-- Ball National Capital Chapter National Multiple National Capital Chapter's $10,000.00 Sclerosis Society-- Walk MS 2015 National Capital Chapter National Multiple National Capital Chapter's $5,000.00 Sclerosis Society-- Walk MS 2015 National Capital Chapter National Multiple 11th Annual Women On The Move $5,000.00 Sclerosis Society-- Luncheon National Capital Chapter National Multiple Bike MS Ride the Vine Event $5,000.00 Sclerosis Society-- National Capital Chapter National Multiple A Day for Men Living with MS $1,500.00 Sclerosis Society-- Program National Capital Chapter National Multiple Bike MS 'I Ride with MS' $600,000.00 Sclerosis Society--New Program York, NY National Multiple The International Progressive $100,000.00 Sclerosis Society--New MS Alliance 2015 York, NY National Multiple National MS Society E- $75,000.00 Sclerosis Society--New Communications Program York, NY National Multiple North American Education $35,000.00 Sclerosis Society--New Program for people with MS York, NY and their families National Multiple Knowledge is Power 2015 at $35,000.00 Sclerosis Society--New Home Educational series York, NY National Multiple MS Navigator: Information $25,000.00 Sclerosis Society--New Program York, NY National Multiple National MS Society $25,000.00 Sclerosis Society--New educational video York, NY programming for people with MS and their families through ``MS Learn Online'' National Multiple 2015 National MS Society, $15,000.00 Sclerosis Society--New Southern NY Chapter York, NY Scholarship Program National Multiple 2015 Women on the Move $12,000.00 Sclerosis Society--New Program York, NY National Multiple 2015 Gala/Dinner of Champions $12,000.00 Sclerosis Society--New York, NY National Multiple Research Symposium 2015: MS $3,000.00 Sclerosis Society--New Research Discoveries: York, NY Wellness and Treatments for Living Your Best Life National Multiple Medical Student Clinical $1,500.00 Sclerosis Society--New Summer Fellowship York, NY National Multiple MS Awareness and Education $15,000.00 Sclerosis Society--NJ Newsletter Metro Chapter National Multiple New Jersey Metro Chapter's $10,000.00 Sclerosis Society--NJ Walk MS 2015 Metro Chapter National Multiple Northern California Chapter's $25,000.00 Sclerosis Society-- Walk MS 2015 Northern California National Multiple Chapter DuskBuster 5k Race $2,500.00 Sclerosis Society-- Event Northern California National Multiple Ohio Valley Chapter's Walk MS $10,000.00 Sclerosis Society-- 2015 Ohio Valley Chapter National Multiple Women on the Move Luncheon $2,500.00 Sclerosis Society-- and Fashion Show Ohio Valley Chapter National Multiple Lydia Emily ``Make Your Mark $33,554.00 Sclerosis Society-- on MS'' Mural Project that Oregon Chapter will provide hope to the local MS community and greatly increase public awareness of MS National Multiple Oregon Chapter's Walk MS 2015 $10,000.00 Sclerosis Society-- Oregon Chapter National Multiple Bike MS 2015: Willamette $5,000.00 Sclerosis Society-- Valley Oregon Chapter National Multiple Gala MS 2015 $5,000.00 Sclerosis Society-- Oregon Chapter National Multiple Relationship Matters--Spring $5,000.00 Sclerosis Society-- 2015 Oregon Chapter National Multiple Greater Delaware Valley and $7,500.00 Sclerosis Society-- Delaware Chapter's Walk MS Philadelphia, PA 2015 National Multiple Women Against MS Luncheon-- $2,500.00 Sclerosis Society-- Patient Wellness Program Philadelphia, PA National Multiple Pennsylvania Keystone $25,000.00 Sclerosis Society-- Chapter's Walk MS Champaign Pittsburgh, PA (to include 23 Walk Events) National Multiple Walk MS 2015 $10,000.00 Sclerosis Society-- Rochester, NY National Multiple 2015 National MS Society, $7,000.00 Sclerosis Society-- Upstate NY Chapter Rochester, NY Scholarship Program National Multiple Bike MS Event $5,000.00 Sclerosis Society-- Rochester, NY National Multiple 2015 MS Research Nights $5,000.00 Sclerosis Society-- Rochester, NY National Multiple Champions On the Move $3,000.00 Sclerosis Society-- Luncheon Rochester, NY National Multiple 8th Annual Hudson Valley $3,000.00 Sclerosis Society-- Multiple Sclerosis Symposium Rochester, NY National Multiple 2015 Health and Wellness Fair $2,000.00 Sclerosis Society-- Rochester, NY National Multiple Everyday Matters: Living Your $2,000.00 Sclerosis Society-- Best Life with MS Program Rochester, NY National Multiple On the Move Luncheon program $1,500.00 Sclerosis Society-- to raise funds and awareness Rochester, NY for Multiple Sclerosis National Multiple MS Service Day--Patient $1,000.00 Sclerosis Society-- Assistance Program Rochester, NY National Multiple Free From Falls--Patient $750.00 Sclerosis Society-- Wellness Program Rochester, NY National Multiple Utah-Southern Idaho Walk MS $15,000.00 Sclerosis Society-- 2015 Salt Lake City, UT National Multiple Women on the Move Luncheon $2,500.00 Sclerosis Society-- and Fashion Show 2015 Salt Lake City, UT National Multiple Walk MS San Diego $15,000.00 Sclerosis Society--San Diego, CA National Multiple 28th Annual MS Dinner Charity $10,000.00 Sclerosis Society--San Auction Diego, CA National Multiple MS Dinner Auction Hawaii $5,000.00 Sclerosis Society--San Diego, CA National Multiple UC Irvine Lunch & Learn $4,000.00 Sclerosis Society--San Symposium Diego, CA National Multiple Challenge Walk MS $2,500.00 Sclerosis Society--San Diego, CA National Multiple South Florida Chapter's Walk $25,000.00 Sclerosis Society-- MS 2015 South Florida Chapter National Multiple MS Gala Luncheon 2015 $10,000.00 Sclerosis Society-- South Florida Chapter National Multiple Festival Hispano 2015-- $4,000.00 Sclerosis Society-- Patient Awareness Program South Florida Chapter National Multiple Mind, Body & Soul--ESTERO $1,500.00 Sclerosis Society-- Event South Florida Chapter National Multiple Mind, Body & Soul--Boca Raton $1,500.00 Sclerosis Society-- Event South Florida Chapter National Multiple Walk MS: North Dakota Walks, $5,500.00 Sclerosis Society-- South Dakota Walks, and Twin Upper Midwest Chapter Cities Challenge Walk National Multiple Upper Midwest Chapter's Walk $5,000.00 Sclerosis Society-- MS 2015 Upper Midwest Chapter National Multiple Taste of Generosity Gala $2,500.00 Sclerosis Society-- Dinner Upper Midwest Chapter National Multiple St. Cloud MS Walk 2015 $1,000.00 Sclerosis Society-- Upper Midwest Chapter National Multiple Wisconsin Chapter's Walks MS $10,000.00 Sclerosis Society-- 2015 (to include 20 Walk Wisconsin Chapter Events) National Multiple Georgia Chapter's Walk MS $5,000.00 Sclerosis Society-- 2015 Georgia Chapter National Multiple Bike MS Cape Cod Getaway, the $50,000.00 Sclerosis Society-- largest MS ride in New Greater New England England Chapter National Multiple MileStones 2015 Program Ad $5,000.00 Sclerosis Society- Greater New England Chapter National Multiple Greater Northwest Chapter's $25,000.00 Sclerosis Society- Walk MS Events Greater Northwest Chapter National Multiple Bike MS Race Event: I Ride $10,000.00 Sclerosis Society- with MS Greater Northwest Chapter National Multiple Mood & Cognition in MS: What $8,230.00 Sclerosis Society- you can do--Patient Wellness Greater Northwest Program Chapter National Multiple Northwest Chapter's Dinner of $2,500.00 Sclerosis Society- Champions Gala Greater Northwest Chapter National Multiple Indiana Chapter's Walk MS $8,500.00 Sclerosis Society 2015 Indiana State Chapter National Multiple Society's Financial Patient $5,000.00 Sclerosis Society Assistance Program Indiana State Chapter National Multiple MS Navigator: Information $5,000.00 Sclerosis Society Program Indiana State Chapter National Multiple 39th Annual Dinner of $5,000.00 Sclerosis Society--Los Champions Angeles, CA National Multiple Everyday Matters Patient $909.00 Sclerosis Society-- Wellness Program Upstate New York Chapter National Niemann-Pick Hope is on the Horizon Family $30,000.00 Disease Foundation Patient Services Program National Organization Portraits of Courage 2015 $50,000.00 for Rare Disorders National Organization Volunteer Match $9,000.00 for Rare Disorders National Organization Rare Disease Day Relay $6,000.00 for Rare Disorders National Organization NORD's Rare Diseases and $50,000.00 for Rare Disorders, Orphan Products Breakthrough Inc. Summit National Tay-Sachs & Imagine & Believe 2015 Event $10,000.00 Allied Diseases Association, Inc. National Tay-Sachs & 37th Annual Family Conference $5,000.00 Allied Diseases Association, Inc. National Tay-Sachs & Raising Awareness of $1,200.00 Allied Diseases Ashkenazi Jewish Genetic Association, Inc. Diseases through the Forward's annual genetics issue Nebraska Kidney Patient & Family Education $500.00 Association Day Neurologic Disease MS: Today and Tomorrow $5,995.00 Foundation Caregiver Wellness Program Neurologic Disease Newly Diagnosed MS Patient $4,995.00 Foundation Educational Series 2015 Neuropathy Action 9th Annual Neuropathy Action $2,500.00 Foundation Awareness Day New England Healthcare The Nick Littlefield Health $25,000.00 Institute Policy Fellowship New England Healthcare Innovators in Health Awards $25,000.00 Institute Next Step Fund Inc. Expansion of year-round $10,000.00 programming in Song.Studio and the Media Lab for youth with rare genetic disorders Norton Healthcare 2015 Neuro Expo $10,000.00 Foundation, Inc. OhioHealth Corporation OhioHealth Multiple Sclerosis $20,000.00 Patient Education Program Oligonucleotide 11th Annual Meeting of the $2,500.00 Therapeutic Society Oligonucleotide Therapeutics Society Operation Warm Inc. Community support for Boston $15,000.00 Warmth in Winter Oregon Health & Science At the Frontier & Beyond: MS $8,850.00 University 2015 Oregon Health & Science On the Horizon: Updates in $8,700.00 University Multiple Sclerosis Our Space Inc. Volunteer Match $1,000.00 Partners Healthcare World Medical Innovation $50,000.00 System, Inc. Forum--Neurosciences Patient Access Network Patient Assistance Program $260,000.00 Foundation for Homozygous Familial Hypercholesterolemia (HoFH) Patients Patient Access Network Patient Assistance Program $125,000.00 Foundation for Patients with Thyroid Cancer Patient Access Network Patient Assistance Program $50,000.00 Foundation for Homozygous Familial Hypercholesterolemia (HoFH) Patients Patient Access Network Patient Assistance Program $50,000.00 Foundation for Homozygous Familial Hypercholesterolemia (HoFH) Patients Patient Services Inc. Fabry Financial Patient $3,150,000.00 Assistance Program Patient Services Inc. Pompe Patient Assistance $237,422.00 Program Patient Services Inc. Pompe Patient Assistance $237,422.00 Program Patient Services Inc. MPS1 Patient Assistance $212,778.00 Program Patient Services Inc. Patient Assistance Program $212,378.00 for Gauchers Disease Peer Health Exchange Peer Health Exchange: $5,000.00 Inc. Empowering Boston Youth to Make Healthy Decisions Perkins School for the Perkins eLearning: Accessible $20,000.00 Blind Science Education Pharmacy Quality Development of Quality $75,000.00 Alliance Measurement Strategy for Multiple Sclerosis Program Phillips Brooks House Put on a Helmet! $5,755.76 Association Incorporated Portland VA Research PDX Patient Workshop $4,000.00 Foundation Inc. Pro Player Foundation Flavors of Austin hosted by $5,000.00 Earl Campbell Project Eden Inc. Volunteer Match $1,000.00 Race--Run Against Super Sunday 5K Sponsorship $10,000.00 Cancer Events Race to Erase MS 22nd Annual Race to Erase MS $60,000.00 Resolve Community Volunteer Match $1,000.00 Counseling Center, Inc. Rhode Island Rare World Rare Disease Dar Art $5,000.00 Disease Foundation Exhibit 2015 Rhode Island Rare Beyond the Diagnosis Art $2,500.00 Disease Foundation Exhibit Rocky Mountain Multiple Rocky Mountain MS Center $5,000.00 Sclerosis Center Annual Gala Room to Grow Clinical Community Support $5,000.00 Program S S Cosmas & Damian 88th Annual East Cambridge $2,500.00 Society Inc. Festival Samaritans of Greater Community Support for Youth $25,000.00 Boston Suicide Prevention Program Science Club For Girls Campus Chapters Supporting K- $10,000.00 Inc. 12 Science Clubs Science From Scientists 69th Annual Boston Citywide $10,000.00 Inc. Science Fair Seattle Children's MPS Family Day 2015 $6,000.00 Hospital Foundation Special Olympics Bio-Ball 2015 $2,000.00 Massachusetts Inc. Stop Hunger Now, Inc. Meal Packaging Event--Take $3,044.08 Our Sons & Daughters to Work Day Student Clubs of HBS, 12th Annual Healthcare $1,500.00 Inc. Conference at Harvard Business School Temple University Genzyme Allston/Brighton $5,000.00 Biotechnology College Scholarship Terrapinn Inc. World Orphan Drug Congress $50,000.00 USA 2015 Texas Neurological TNS 18th Annual Winter $5,000.00 Society Conference THANC Foundation, Inc. A Starry Night to benefit the $5,000.00 THANC (Thyroid, Head and Neck Cancer) Foundation honoring R. Michael Tuttle, MD THANC Foundation, Inc. A Starry Night to benefit the $5,000.00 THANC (Thyroid, Head and Neck Cancer) Foundation honoring R. Michael Tuttle, MD The Boston Home, Inc. B.Fit! Day Wellness Program $18,000.00 The Boston Home, Inc. iPads Communication System $12,000.00 for Wheelchair Users-- Patient Assistance Program The Boston Home, Inc. The Boston Home Art Program $10,000.00 The Boston Home, Inc. Volunteer Match $1,000.00 The Community Art Community Teen Media Program $10,000.00 Center The Familial FH Patient Speakers Bureau $25,000.00 Hypercholesterolemia Program Foundation The Familial Homozygous Familial $20,000.00 Hypercholesterolemia Hypercholesterolemia (HoFH) Foundation Community Program The FH Foundation 2015 FH Global Summit $25,000.00 The Forsyth Institute The ForsythKids School Oral $10,000.00 Health Program: Expansion to serve Homeless Youth in Cambridge The Friends of the Community Support of The $4,000.00 Hopkinton Public Friends of the Hopkinton Library Public Library The Life Sciences Leadership Mid-Term Funding $50,000.00 Foundation for Educational Programs The McCourt Foundation MS Educational Update Program $20,000.00 The McCourt Foundation McCourt Foundation Gala & $15,000.00 Auction The McCourt Foundation Tour de South Shore Bike $10,000.00 Event The McCourt Foundation The Immune System and The $5,000.00 Brain With a Focus on MS The National Cancer Gaucher's Disease Relief $5,000.00 Coalition, Inc. Patient Assistance Program The Oak Clinic 2015 Diamond Run for MS $5,000.00 The Posse Foundation Community Support for Posse $20,000.00 Boston's Students Program Thompson Island Outward Connections--STEM learning to $10,000.00 Bound Education Center empower urban youth Inc. Thyca Thyroid Cancer 18th International Thyroid $30,000.00 Survivors Association Cancer Survivors' Conference Inc. Thyca Thyroid Cancer Informational Resource $7,875.00 Survivors Association Support for ``After the Inc. Diagnosis, Medullary Thyroid Cancer Memoirs'' to all ThyCa Support Group Tisch Multiple 18th Annual Patient Symposium $30,000.00 Sclerosis Research Center of New York, Inc. Tisch Multiple Healing MS Patient Newsletter $15,000.00 Sclerosis Research Center of New York, Inc. Trustees of Boston Genzyme Youth Science & $5,050.00 University Engineering Workshop Scholarships for U-Design Program at Boston University Trustees of Boston Genzyme Allston/Brighton $2,000.00 University Biotechnology College Scholarship Trustees of Boston Genzyme Allston/Brighton $2,000.00 University Biotechnology College Scholarship Trustees of Tufts Genzyme Allston/Brighton $5,000.00 College Biotechnology College Scholarship Tutoring Plus of Science & Math Enrichment $5,000.00 Cambridge, Inc. Programs Tutoring Plus of Volunteer Match $1,000.00 Cambridge, Inc. United Pompe Foundation Pompe Community Support $46,500.00 Programs United Pompe Foundation Duke Late Onset Pompe Patient $20,000.00 Meeting United Way of Tri Volunteer Match $1,000.00 County Inc. University of Florida 8th International Conference $2,000.00 on Unstable Microsatellites and Human Disease University of Massachusetts STEM Summit $10,000.00 Massachusetts 2015: Promising Practices, Proven Results University of Student Success Program for $200,000.00 Massachusetts UMass Boston, College of Foundation Inc. Science and Mathematics University of Southern Genzyme Allston/Brighton $5,000.00 California Biotechnology College Scholarship Urban Kidney Alliance, Prescription Medication $500.00 Inc. Assistance Program (PMAP) Veterans Inc. Volunteer Match $1,000.00 Visiting Nurse Heroes in Health Care Gala $10,000.00 Association of Boston & Affiliates Weill Medical College Talk MS Program $10,000.00 of Cornell University West County MS Center 10th Annual Trivia and $7,500.00 Auction West End House Boys and Volunteer Match $1,000.00 Girls Club WGBH WGBH Pledge Night $12,000.00 Whitehead Institute for Whitehead Institute's 2015 $10,000.00 Biomedical Research CampBio Program Whitehead Institute for Whitehead Institute's 2016 $10,000.00 Biomedical Research CampBio Program Women's Lunch Place Community Support for Meals $35,000.00 Program Worcester County Food Volunteer Match $1,000.00 Bank Inc. Worcester Polytechnic Genzyme Allston/Brighton $1,000.00 Institute Biotechnology College Scholarship WriteBoston STEM Teacher Excellence: $10,000.00 Powered By Genzyme Wylder Nation 2nd Annual Living Like a $10,000.00 Foundation Warrior Gala YMCA of Greater Boston Oak Square YMCA--Summer Day $15,000.00 Camp Scholarship Sponsorships and Charitable Donations 1st Jan 2016-31st Dec 2016 Sanofi US and its affiliate Genzyme Corporation are committed to supporting sponsorships for specific activities and initiatives of healthcare organizations and institutions, independent medical or professional societies, trade organizations and organized patient groups to improve patient care and provide information to the medical and/or patient communities. The goal of our charitable giving approach is to fund general operational support for patient/disease organizations, or program support for community-based organizations. Sanofi US and Genzyme Corporation are part of the Sanofi Group, a global pharmaceutical company. Applicant names are provided by the requestor. If applicants apply as a group for a single activity; all applicants may be not be identified above. ``Funding Amount'' is the amount that the Company funded during 2015 identified above. ``Funding Amount'' does not include funds that may have been provided by other affiliated Sanofi Company Entities (e.g., Sanofi Pasteur). Recipient Name(s) Activity Title Funding Amount Acid Maltase Deficiency General Operating Support $48,000.00 Association Inc. ACTRIMS Congress Sponsorships $30,000.00 Allston Brighton Feastworthy: Pilot Prepared $15,000.00 Community Development Meals Delivery Program Corporation American Academy of Congress Sponsorships $482,897.00 Neurology Institute American Academy of Palatucci Advocacy Leadership $50,000.00 Neurology Institute Forum American Academy of Brain Health Fair $7,500.00 Neurology Institute American Academy of Fellows Scholarship Fund $20,000.00 Neurology Institute American Academy of Residents Scholarship Fund $20,000.00 Neurology Institute American Academy of Emerging Leaders Program $20,000.00 Neurology Institute American Association of Congress Sponsorships $4,300.00 Clinical Endocrinologists American Association of Fabry Family Member Testing $164,970.00 Kidney Patients and Education Project American Autoimmune and 50 Cents for 50 Million $5,000.00 Related Diseases Laughs Campaign Association American Brain Patient Advocacy Organization $5,000.00 Coalition Membership Sponsorship American Cancer Society Volunteer Match $1,000.00 American Cancer Society Volunteer Match $11,000.00 American Chemical Recovery of Biological $5,000.00 Society Merck and Co Products XVII Conference Inc. American Chemical Biochemical Technology ACS $5,000.00 Society Merck and Co National Meeting Inc. American College of Congress Sponsorships $50,875.00 Medical Genetics and Genomics American Red Cross of American Red Cross Blood $5,000.00 Massachusetts Services American Red Cross of American Red Cross of $5,000.00 Massachusetts Massachusetts Women Who Care Breakfast American Thyroid Congress Sponsorships $3,000.00 Association American Thyroid Congress Sponsorships $15,000.00 Association ANERA (American Near ANERA Annual Dinner $5,000.00 East Refugee Aid) Angel's Hands Family Assistance Program $5,000.00 Foundation Ann & Robert H. Lurie MPS Patient and Family $2,000.00 Children's Hospital of Conference Chicago Arthritis Foundation Orange County & Inland Empire $2,500.00 Jingle Bell Run Assistance Fund Inc. Patient Assistance Program $7,750,000.00 for MS Association For Annual Conference; Family $6,000.00 Glycogen Storage Assistance; The Ray Disease (newsletter) Association For Annual Conference; Family $6,000.00 Glycogen Storage Assistance; The Ray Disease (newsletter) Barth Syndrome Barth Syndrome Foundation $2,000.00 Foundation Conference Batten Disease Support NCL Congress Boston $5,000.00 And Research Association Berkshire Resource 8th Annual GALA Fundraiser $5,000.00 Project Berkshire Resource When IWalk - An MS Story $8,000.00 Project Big Brothers Big MySTEM--Mentoring Youth in $10,000.00 Sisters Of Central Science, Technology, Mass Metrowest Inc. Engineering, and Mathematics Biomedical Science Hope Scholarship $7,500.00 Careers Program Biomedical Science Evening of Hope $75,000.00 Careers Program Biotechnology BIO Patient and Health $10,000.00 Innovation Advocacy Summit Organization Boston Area Rape Crisis Community Program $25,000.00 Center Boston Area Rape Crisis Advocacy Program $25,000.00 Center Boston College Trustees Allston Brighton College $2,000.00 Scholarship Boston College Trustees Allston Brighton College $4,000.00 Scholarship Boston Educational Boston Public Schools Science $10,000.00 Development Fair Foundation, Inc. Boston Health Care For Life Essentials for Homeless $35,000.00 The Homeless Program Patients Inc. Boston Health Care For Volunteer Match $1,000.00 The Homeless Program Inc. Boston Health Care For General Operating Support $10,000.00 The Homeless Program Inc. Boston Partners in Power Lunch Program $6,000.00 Education, Inc. Boston Private Industry Corporate Contributions $15,000.00 Council Campaign Boston Private Industry Volunteer Match $1,000.00 Council Bottom Line Boston STEM Success Program $15,000.00 Bottom Line Volunteer Match $1,000.00 Boys and Girls Clubs of Staffing & Transportation for $25,000.00 MetroWest Membership at BGCMW's Framingham Clubhouse Boys and Girls Clubs of Volunteer Match $1,000.00 MetroWest Boys and Girls Clubs of Volunteer Match $4,000.00 MetroWest Boys and Girls Clubs of Volunteer Match $1,000.00 MetroWest Boys and Girls Clubs of Bids for Kids Auction & Gala $10,000.00 MetroWest Boys and Girls Clubs Of Great Pumpkin Glow $6,000.00 Middlesex County Inc. BPE Boston Teacher Residency: $15,000.00 Putting Students at the Center of STEM Teacher Training Breakthrough Greater Full STEAM Ahead Program With $10,000.00 Boston Low-Income Students Brian J. Honan Brian Honan 5K Road Race $2,500.00 Charitable Fund California Association Congress Sponsorships $1,500.00 of Physician Groups (CAPG) California Association Congress Sponsorships $1,000.00 of Physician Groups (CAPG) California District Congress Sponsorships $3,000.00 American Academy of Pediatrics California Pharmacists Congress Sponsorships $1,500.00 Association Educational Foundation Cambridge Chamber of Women in Business Programming $4,350.00 Commerce Series Sponsor Cambridge Health Volunteer Match $1,000.00 Alliance Foundation Inc. Cambridge School Volunteer Match $1,000.00 Volunteers, Inc. Cambridge School Volunteer Match $15,825.00 Volunteers, Inc. Cambridge School Volunteer Match $13,755.00 Volunteers, Inc. Cambridge School Community Program $11,000.00 Volunteers, Inc. Cambridge School Community Program $11,000.00 Volunteers, Inc. Camp Korey Metabolic Disorders Family $5,000.00 Weekend Camp Can Do Multiple JUMPSTART Programs $60,000.00 Sclerosis Can Do Multiple Annual Autumn Benefit for Can $5,000.00 Sclerosis Do Multiple Sclerosis Can Do Multiple Vertical Express for Can Do $30,000.00 Sclerosis MS Can Do Multiple Annual Autumn Benefit $10,000.00 Sclerosis Can Do Multiple CAN DO Program $60,000.00 Sclerosis Can Do Multiple TAKE CHARGETM Program $37,500.00 Sclerosis Case Management Society CMSA 26th Annual Conference & $4,650.00 of America Expo Case Management Society Congress Sponsorships $14,000.00 of America Case Management Society Congress Sponsorships $5,500.00 of America Case Management Society New Frontiers of $1,050.00 of New England Technological Advancement Program Case Management Society Corporate Sponsorship of $1,250.00 of New England CMSNE Case Management Society Creativity, Inspiration & $1,000.00 of New England Collaboration: Building Blocks of Successful Leadership CASSS--An International WCBP--20th Symposium $7,500.00 Separation Science Society Charles River Community Mom & Baby Program $15,000.00 Health Charles River Volunteer Match $1,000.00 Conservancy Charles River Volunteer Match $4,000.00 Conservancy Chelsea Jewish Nursing ALS & MS Walk for Living $2,500.00 Home Foundation, Inc. Childrens Gaucher Gaucher Related Research Fund $75,000.00 Research Fund Children's Hospital La Gala de Milagros para $5,000.00 Boston Ninos Children's Hospital Volunteer Match $1,000.00 Boston Children's Hospital of Lysosomal Day at The $16,370.33 Philadelphia Philadelphia Zoo Foundation Chronic Disease Fund, Medullary Thyroid Cancer $300,000.00 Inc DBA Good Days from Patient Assistance Program CDF Chronic Disease Fund, Medullary Thyroid Cancer $150,000.00 Inc DBA Good Days from Patient Assistance Program CDF Church Hillers Inc. Volunteer Match $1,000.00 Cincinnati Children's Meeting for Patients with $5,000.00 Hospital Medical Fabry Disease Center Citizen Schools Expanding STEM Learning at $15,000.00 Boston Schools Citizen Schools Deepening the Impact of STEM $15,000.00 Education City Sprouts, Inc. CitySprouts Middle School $8,000.00 Program in Cambridge City Sprouts, Inc. CitySprouts Middle School $8,000.00 Program Cleveland Clinic Multiple Sclerosis (MS) $10,125.00 Foundation Promoting Wellness and Healthy Lifestyle Community Boating, Inc. Universal Access Program 2016 $15,000.00 Community Farms Fresh Food Access Program $15,000.00 Outreach Community Living and The Giving Tree Campaign $6,500.00 Support Services, Inc. Community Rowing, Inc. Let's Row Boston $10,000.00 Community Servings, Pie in the Sky $10,000.00 Inc. Consortium of MS Congress Sponsorships $5,000.00 Centers Courageous Parents Patient Education and $7,000.00 Network Awareness Program Cradles To Crayons Inc. Ready for School $20,000.00 Cradles To Crayons Inc. General Operating Support $10,000.00 Cradles To Crayons Inc. Volunteer Match $1,000.00 Cystic Fibrosis Volunteer Match $4,000.00 Foundation Cystic Fibrosis Uncork the Cure $10,000.00 Foundation Damon Runyon Cancer General Operating Support $5,000.00 Research Foundation DEAF, Inc.-- Community Program $10,000.00 Developmental Evaluation and Adjustment Facilities, Inc. Dimock Community Health 29th Annual Steppin' Out for $25,000.00 Center The Dimock Center Dimock Realty Building the Road to Recovery $50,000.00 Corporation Campaign Direct Relief Patient Assistance Fund for $10,000.00 International Rare Diseases Direct Relief Patient Assistance Fund for $5,000.00 International Rare Diseases DPC Education Center Fabry Disease Newsletter $25,000.00 Support Duke University Patient Assistance Program $400,000.00 Duke University Hospitals Patient Assistance $224,000.00 Program East End House Inc. Generating and Evaluating New $20,000.00 Adventures in Science After School (GENASAS) East End House Inc. Generating and Evaluating New $20,000.00 Adventures in Science After School (GENASAS) Engineering Conferences Cell Culture Engineering XV $10,000.00 International Conference EveryLife Foundation Community Congress $15,000.00 for Rare Diseases EveryLife Foundation Rare Disease Advocacy Program $20,000.00 for Rare Diseases EveryLife Foundation Rare Voice Awards $15,000.00 for Rare Diseases EveryLife Foundation Patient Education and $5,000.00 for Rare Diseases Awareness Program EveryLife Foundation Community Congress $5,000.00 for Rare Diseases Fabry Support & Fabry Support &Information $30,000.00 Information Group Group Patient Assistance Fund Program Fabry Support & Fabry Support & Information $100,000.00 Information Group Group General Operating Support Fabry Support & Fun Run/Walk St. Louis, MO $1,500.00 Information Group Fabry Support & FSIG Expert Fabry Conference $50,000.00 Information Group Families of SMA Annual SMA Conference $10,000.00 Family Promise Keep the Promise, Food $2,500.00 Metrowest Inc. Program for the Homeless Florida Society of Congress Sponsorships $15,000.00 Rheumatology Food For Free Community Program $1,000.00 Committee, Inc. Foundation Fighting Volunteer Match $2,000.00 Blindness Inc. Framingham Townwide Pto Volunteer Match $1,000.00 Council Franciscan Hospital For Adaptive Sports Program $10,000.00 Children Inc. Friends of Resiliency Community Program $10,000.00 for Life Inc. Friends of Resiliency Volunteer Match $1,000.00 for Life Inc. Generation Citizen Inc. Spring and Fall Civics Day $5,000.00 Genetic Alliance Inc. Industry Program $20,000.00 Girl Scouts of Eastern Girls Building Self-eSTeEM $10,000.00 Massachusetts Inc. Girl Scouts of Eastern Volunteer Match $1,000.00 Massachusetts Inc. Girl Scouts of Eastern Volunteer Match $1,000.00 Massachusetts Inc. Global Genes RARE Tribute To Champions of $25,000.00 Hope Global Genes RARE Webinars & RARE Toolkits $30,000.00 Global Genes Patient Assistance Program $20,000.00 Global Genes RARE Patient Advocacy Summit $25,000.00 Gordon Research Barriers of the Central $2,000.00 Conferences Nervous System Gordon Research Conference Greater Boston Chamber Annual Meeting $10,000.00 of Commerce Habitat For Humanity Home Build for Four Low- $20,000.00 Metrowest--Greater Income Families Program Worcester Inc. Habitat For Humanity Volunteer Match $1,000.00 Metrowest--Greater Worcester Inc. Habitat For Humanity Volunteer Match $1,500.00 Metrowest--Greater Worcester Inc. Habitat For Humanity Volunteer Match $2,000.00 Metrowest--Greater Worcester Inc. Habitat For Humanity High Heels and Hard Hats $7,500.00 Metrowest - Greater Auction and Gala Worcester Inc. Harvard College Allston Brighton College $2,000.00 Scholarship Health Care For All Public Education Campaign to $15,000.00 Inc. Improve Access to Health Care in Framingham Health Resources In The Leaders through $20,000.00 Action Inc. Education, Action and Hope (LEAH) Project Health Resources in The Leaders through $20,000.00 Action Inc. Education, Action, and Hope (LEAH) Project Hearts & Noses Hospital Hospital Clown Visits to Ill $15,000.00 Clown Troupe Inc. and Disabled Children in Greater Boston Hereditary Disease Milton Wexler Celebration of $5,000.00 Foundation Life Symposium Holy Name Health Care MS Awards Reception $2,500.00 Foundation Inc. Holy Name Health Care 19th Annual spring Fling to $5,000.00 Foundation Inc. benefit MS Holy Name Health Care MS Awards Reception $5,000.00 Foundation Inc. Horizons for Homeless 18th Annual Women's Breakfast $5,000.00 Children Huntington's Disease Patient Education and $5,000.00 Society of America Awareness Program Huntington's Disease Huntington's Disease Society $2,000.00 Society of America of America 31st Annual Convention International Institute Patient Navigation Services $10,000.00 of New England for Refugees in Boston International Institute Golden Door Award Gala $10,000.00 of New England International Stress--You Can't Avoid It, $10,000.00 Organization of But You Can Manage It! Multiple Sclerosis Nurses International Annual Meeting IOMSN Dinner $30,000.00 Organization of Multiple Sclerosis Nurses International MS Perspectives $75,000.00 Organization of Multiple Sclerosis Nurses Italian Home For Annual Gala $5,000.00 Children Inc. Jewish Family Service Patient Navigator Program $15,000.00 of Metrowest Inc. Jewish Family Service Patient Navigator Program $15,000.00 of Metrowest Inc. Jewish Genetic Disease Community and Rabbinic $500.00 Consortium (JGDC) Education for Jewish Genetic Diseases Just-A-Start St. Patrick's Fund $5,000.00 Corporation Just-A-Start Biomedical Careers Program $22,950.00 Corporation LGMD2D Foundation Patient Assistance Program $650,000.00 LGMD2D Foundation Patient Assistance Program $600,000.00 Light of Life Light of Life Foundation $40,000.00 Foundation Program Little Brothers/Friends Community Program $7,500.00 of the Elderly Louisiana Association Congress Sponsorships $5,285.00 of Health Plans MagellanRx Management Congress Sponsorships $5,000.00 Manchaug Pond Volunteer Match $1,000.00 Association March of Dimes Volunteer Match $2,000.00 March of Dimes Black Ties for Babies $10,000.00 March of Dimes March for Babies $15,000.00 Margaret Fuller Please Help a Crumbling $20,000.00 Neighborhood House Community Resource Margaret Fuller Margaret Fuller Kids Summer $15,000.00 Neighborhood House Explorations Program Mass Insight Education Advanced Placement (AP) $15,000.00 and Research Institute Science, Technology, Inc. Engineering, and Math (STEM) and English Program Massachusetts Bay STEM Mentor Program (SMP) $37,000.00 Community College Foundation Massachusetts Congress Sponsorships $25,000.00 Biotechnology Council Massachusetts Patient Advocacy Summit $10,000.00 Biotechnology Council Massachusetts MassBio Annual Meeting $10,000.00 Biotechnology Council Massachusetts 2016 MassBio Policy $5,000.00 Biotechnology Council Leadership Breakfast Massachusetts Volunteer Match $1,000.00 Biotechnology Education Foundation Inc. Massachusetts BioTeach $50,000.00 Biotechnology Education Foundation Inc. Massachusetts Volunteer Match $1,000.00 Biotechnology Education Foundation Inc. Massachusetts Champions for Biotechnology $2,500.00 Biotechnology Education Program Education Foundation Inc. Massachusetts Black Massachusetts Black Women $5,000.00 Women Attorneys Attorneys 35th Anniversary Foundation Inc. Celebration Massachusetts College Next Generation of Women $10,000.00 of Pharmacy and Health Leaders in STEM Sciences Massachusetts Institute Cambridge Science Festival $5,000.00 of Technology Massachusetts Outdoor Volunteer Match $1,000.00 Heritage Foundation Inc. Massachusetts State Massachusetts State Science & $50,000.00 Science and Engineering Fair Engineering Fair, Inc. Mattel Children's Educational Seminars for $59,000.00 Hospital UCLA Patients with Fabry Disease Mercy Foundation Multiple Sclerosis $25,000.00 Achievement Center Wellness Education Programs Metrowest Free Medical Expanding Access to Women's $10,000.00 Program Inc. Health Care and Health Education in Framingham Miami Childrens Health Education and Outreach $5,000.00 System Foundation Inc. Activities of Jewish Genetic and Pan-Ethnic Diseases Mid America MS The Race to Nowhere $5,000.00 Achievement Center Mid America MS Your MS Depression Toolkit $8,210.00 Achievement Center Mint For Mounts Inc. Volunteer Match $1,000.00 MITS Inc. STEM Professional Development $20,000.00 Institutes for teachers MITS Inc. Professional Development $20,000.00 Institutes for teachers MS Cure Fund Women Thriving with MS--How $125,000.00 to be a partner, a mother, a woman--FIRST MS Cure Fund Lifestyle Management Programs $13,500.00 Spring MS Cure Fund eNewsletter $24,000.00 MS Cure Fund Patient Education and $22,580.00 Awareness Program MS Hope for a Cure Inc. MS Hope Day $10,000.00 MS Views and News Inc. Wheelchairs for Charity $6,000.00 MS Views and News Inc. Effective Communication $19,775.00 Program MS Views and News Inc. Champions Tackling MS Awards $5,000.00 Dinner Gala MS Views and News Inc. Congress Sponsorships $7,900.00 MS Views and News Inc. MS Views and News 6th Annual $3,500.00 Bowlathon Fundraiser MS Views and News Inc. Patient Education and $10,406.75 Awareness Program MS Views and News Inc. 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MSWorld Conference Coverage $12,000.00 Multiple Sclerosis Patient Assistance Program $125,000.00 Association of America Multiple Sclerosis MSAA Cooling Equipment $15,000.00 Association of America Distribution Program Multiple Sclerosis Patient Assistance Program $50,000.00 Association of America Multiple Sclerosis Navigating MS Program $75,000.00 Association of America Multiple Sclerosis ``MS Health and Wellness'' $20,000.00 Association of America Program Multiple Sclerosis Patient Education and $105,000.00 Association of America Awareness Program Multiple Sclerosis MSAA's Improving Lives $10,000.00 Association of America Benefit Multiple Sclerosis MSAA Annual Healthcare $24,887.00 Association of America Advisory Council Summit Multiple Sclerosis Patient Education and $17,409.50 Association of America Awareness Program Multiple Sclerosis MS Fest $10,000.00 Center of Georgia Multiple Sclerosis Health, Hope & Hops $7,000.00 Center of Georgia Multiple Sclerosis Health, Hope & Hops $7,000.00 Center of Georgia Multiple Sclerosis Multiple Sclerosis $50,000.00 Foundation Foundation's Assistive Technology Program Multiple Sclerosis EmpowerSource Support Group $28,000.00 Foundation Newsletter Multiple Sclerosis Chapter Meetings Support $7,000.00 Foundation Multiple Sclerosis National March MS Education $40,000.00 Foundation and Awareness Monthr 2016 Multiple Sclerosis MS Dinner of Hope $1,500.00 Resources of Central New York, Inc. 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$1,000.00 Foundation National Fabry Disease Philadelphia Fabry Family $2,200.00 Foundation Meeting National Fabry Disease Family Assistance Program $10,000.00 Foundation National Fabry Disease Conference and Camp Part 2 $70,000.00 Foundation National Fabry Disease NFDF 2016 Fabry Family $15,000.00 Foundation Educational Meetings National Fabry Disease Urgent and Unmet Needs $40,000.00 Foundation Program National Fabry Disease NFDF Core Program $50,000.00 Foundation National Fabry Disease Fabry Conference and Camp $50,000.00 Foundation National Fabry Disease NFDF Core Program $50,000.00 Foundation National Fabry Disease Volunteer Match $7,000.00 Foundation National Gaucher Patient Assistance CARE $1,200,000.00 Foundation, Inc. Program National Gaucher Patient Assistance Program $400,000.00 Foundation, Inc. National Gaucher Optimal Health Initiative & $225,000.00 Foundation, Inc. Education/Awareness National Kidney South Bend Indiana Kidney $2,500.00 Foundation Program National Kidney Nutrition Program for Chronic $1,000.00 Foundation Kidney Disease, Diabetes and Hypertension National Kidney Indianapolis Kidney Health $1,500.00 Foundation Awareness Program National Kidney Kidney Health Awareness $1,500.00 Foundation Program National Kidney Evansville Kidney Health $1,500.00 Foundation Awareness Program National Kidney Kidney Health Awareness $1,500.00 Foundation Program National Kidney Patient Education and $77,000.00 Foundation Awareness Program National Kidney NKF Clinical Bulletin on $95,775.00 Foundation Fabry Disease National MPS Society Family Support Programs $30,000.00 National MPS Society Symposium funding $4,000.00 National MPS Society National MPS Society $24,000.00 Conferences National MPS Society National MPS Society $24,000.00 Conferences National MPS Society Congress Sponsorships $50,000.00 National MPS Society National Run--National MPS 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Sclerosis Society National Multiple 41st annual Dinner of $2,500.00 Sclerosis Society Champions National Multiple Bike MS: I Ride with MS $5,000.00 Sclerosis Society Greater NW National Multiple Bike MS Cape Cod Getaway $50,000.00 Sclerosis Society National Multiple National MS Society E- $75,000.00 Sclerosis Society Communications Program National Multiple Muckfest MS Boston $25,000.00 Sclerosis Society National Multiple Dinner of Champions Seattle $10,000.00 Sclerosis Society National Multiple Bike MS Ride the Vineyard $10,000.00 Sclerosis Society National Multiple Walk MS Walks MT $5,000.00 Sclerosis Society National Multiple Walk MS Southern California & $25,000.00 Sclerosis Society Nevada National Multiple MS Walks Pacific $10,000.00 Sclerosis Society National Multiple Walk MS Boston $25,000.00 Sclerosis Society National Multiple Fast Forward Research $75,000.00 Sclerosis Society Showcase Meeting National Multiple Bike MS ``I Ride With MS'' NY $350,000.00 Sclerosis Society National Multiple Walk MS Phoenix $5,000.00 Sclerosis Society National Multiple National MS Society Tykeson $10,000.00 Sclerosis Society Fellows Conference National Multiple National MS Society $50,000.00 Sclerosis Society Leadership Conference National Multiple Bike MS Coastal Challenge Los $10,000.00 Sclerosis Society Angeles National Multiple Dinner of Champions Las Vegas $2,500.00 Sclerosis Society National Multiple Are You What You Eat?: $5,000.00 Sclerosis Society Studying Diet and Supplements in Multiple Sclerosis National Multiple National MS Society $15,000.00 Sclerosis Society Leadership Conference National Multiple Live Fully, LiveWell: $15,000.00 Sclerosis Society Discover Your Personal Path to Living Your Best Life with MS National Multiple Chicago Symposium $5,000.00 Sclerosis Society National Multiple MS Walks Greater Houston Area $10,000.00 Sclerosis Society National Multiple Moving Forward: Annual $5,000.00 Sclerosis Society Meeting and Resource Fair National Multiple Bike MS NYC $6,000.00 Sclerosis Society National Multiple Dallas On The Move Luncheon $5,000.00 Sclerosis Society National Multiple MuckFest MS $3,000.00 Sclerosis Society National Multiple Gala MS $2,500.00 Sclerosis Society National Multiple Bike MS: City to Shore Ride $5,000.00 Sclerosis Society National Multiple Crystal Boots & Silver Spurs $2,400.00 Sclerosis Society National Multiple Bike MS--Northern California $5,000.00 Sclerosis Society National Multiple MS Auction Hawaii $3,500.00 Sclerosis Society National Multiple Orange Country MS Research $2,500.00 Sclerosis Society Symposium National Multiple MS Walks Central Texas $2,500.00 Sclerosis Society National Multiple Ambassadors Ball $25,000.00 Sclerosis Society National Multiple Weekend Escape VA $5,000.00 Sclerosis Society National Multiple Cooling Shirts Gel Packs $4,500.00 Sclerosis Society National Multiple Bike MS Willamette Valley $5,000.00 Sclerosis Society National Multiple Smarty Pants Trivia Night $2,500.00 Sclerosis Society National Multiple Spellbound on the Farm $1,500.00 Sclerosis Society National Multiple Bike MS $5,000.00 Sclerosis Society National Multiple MS On the Move Luncheon $2,500.00 Sclerosis Society National Multiple Women Against MS (WAMS) $5,000.00 Sclerosis Society Luncheon PA National Multiple Walk MS Jones Beach $5,000.00 Sclerosis Society National Multiple On The Move Luncheon New $5,000.00 Sclerosis Society Orleans National Multiple Women on the Move Luncheon $6,000.00 Sclerosis Society National Multiple Walk MS PA $5,000.00 Sclerosis Society National Multiple Women on the Move Program $2,500.00 Sclerosis Society National Multiple Walk MS Greater Illinois $50,000.00 Sclerosis Society National Multiple Walk MS Knoxville $750.00 Sclerosis Society National Multiple Walk MS Michigan Chapter $5,000.00 Sclerosis Society National Multiple Walk MS Rochester NY $2,500.00 Sclerosis Society National Multiple Walk MS Denver $20,000.00 Sclerosis Society National Multiple MS Walks 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MS Middle Tennessee $750.00 Sclerosis Society National Multiple Walk MS Kentucky $10,000.00 Sclerosis Society National Multiple Walk MS NY $100,000.00 Sclerosis Society National Multiple Walk MS OH $5,000.00 Sclerosis Society National Multiple Walk MS Jacksonville $7,500.00 Sclerosis Society National Multiple Walk MS Arkansas $3,000.00 Sclerosis Society National Multiple Walk MS New Mexico $2,500.00 Sclerosis Society National Multiple Walk MS Oklahoma $10,000.00 Sclerosis Society National Multiple Walk MS Washington DC $10,000.00 Sclerosis Society National Multiple Walk MS Cincinnati $10,000.00 Sclerosis Society National Multiple Walk MS Memphis $750.00 Sclerosis Society National Multiple Walk MS Louisiana $5,000.00 Sclerosis Society National Multiple Walk MS San Diego $20,000.00 Sclerosis Society National Multiple Women on the Move Louisville $1,000.00 Sclerosis Society National Multiple On The Move Luncheon--Houston $5,000.00 Sclerosis Society National Multiple Walk MS Atlanta $5,000.00 Sclerosis Society National Multiple Walk MS San Antonio $10,000.00 Sclerosis Society National Multiple On the Move Luncheon $3,000.00 Sclerosis Society National Multiple Runway for MS--Fashion Show $2,500.00 Sclerosis Society Luncheon National Multiple Michigan Chapter's Annual $2,500.00 Sclerosis Society Meeting & Recognition Breakfast National Multiple MS Walks Arizona $24,000.00 Sclerosis Society National Multiple Walk MS Alabama Mississippi $7,500.00 Sclerosis Society National Multiple On The Move Luncheon--Baton $2,500.00 Sclerosis Society Rouge National Multiple Walk MS Ft. Lauderdale $15,000.00 Sclerosis Society National Multiple Women Against MS Luncheon TN $2,500.00 Sclerosis Society National Multiple Health Issues in Multiple $9,000.00 Sclerosis Society Sclerosis Hawaii National Multiple 6th Annual Festival Hispano $4,000.00 Sclerosis Society National Multiple MS Gala Luncheon $5,000.00 Sclerosis Society National Multiple New Jersey Metro Chapter $10,000.00 Sclerosis Society Volunteer Program National Multiple Annual Meeting and Education $8,500.00 Sclerosis Society Conferences National Multiple MuckFest MS Houston $2,500.00 Sclerosis Society National Multiple Women Against MS Luncheon $3,000.00 Sclerosis Society (WAMS) National Multiple Fall Crush Nashville $2,500.00 Sclerosis Society National Multiple Walk MS Houston $20,000.00 Sclerosis Society National Multiple FallCrush Nashville $2,500.00 Sclerosis Society National Multiple Symposium Educational $7,500.00 Sclerosis Society Programs National Multiple MuckFest MS $5,000.00 Sclerosis Society National Multiple Team Finish MS at the $3,000.00 Sclerosis Society Hartford Marathon National Multiple Bike MS Louisiana $5,000.00 Sclerosis Society National Multiple Bike MS: City to Shore Ride $5,000.00 Sclerosis Society PA National Multiple San Antonio Bike MS $10,000.00 Sclerosis Society National Multiple New Hampshire Living Well $1,500.00 Sclerosis Society with MS Conference National Multiple Chapter Annual Meeting and $5,000.00 Sclerosis Society Education Program: Contemporary Issues in MS National Multiple Moving Mountains for MS-- $10,000.00 Sclerosis Society Family Weekend Retreat National Multiple Relationship Matters $5,000.00 Sclerosis Society National Multiple MOVING FORWARD $1,500.00 Sclerosis Society National Multiple Men with MS Elevation $10,000.00 Sclerosis Society Conference National Multiple Children's Hope for $3,800.00 Sclerosis Society Understanding Multiple Sclerosis National Multiple MS Research Nights $5,000.00 Sclerosis Society National Multiple Day of Discovery $7,500.00 Sclerosis Society National Niemann-Pick Volunteer Match $1,000.00 Disease Foundation National Niemann-Pick Staying Strong as we $50,000.00 Disease Foundation Persevere in our Quest for a Cure National Organization Volunteer Match $9,000.00 for Rare Disorders, Inc. National Organization Volunteer Match $6,000.00 for Rare Disorders, Inc. National Organization Running For Rare $5,000.00 for Rare Disorders, Inc. National Organization NORD's Rare Diseases and $50,000.00 for Rare Disorders, Orphan Products Breakthrough Inc. Summit National Organization Rare Impact Awards $50,000.00 for Rare Disorders, Inc. National Tay-Sachs & Raising Awareness of $1,100.00 Allied Diseases Ashkenazi Jewish Genetic Association, Inc. Diseases National Tay-Sachs & Expand Family Support Through $5,000.00 Allied Diseases Technology Association, Inc. National Tay-Sachs & Imagine & Believe $10,000.00 Allied Diseases Association, Inc. National Tay-Sachs & 38th Annual Family Conference $5,000.00 Allied Diseases Association, Inc. NCCN Foundation NCCN Guidelines for Patients: $25,000.00 Thyroid Cancer NEHI The Nick Littlefield Health $25,000.00 Policy Fellowship NEHI Innovators in Health Awards $25,000.00 Nephcure Foundation 11th International Podocyte $3,000.00 Conference Neurologic Disease 21st Fall MS Seminar-- $5,995.00 Foundation Optimizing Management of MS Neuropathy Action General Patient Advocacy and $2,500.00 Foundation Organizational Support Next Step Fund Inc. FaceForward Campference and $10,000.00 general operating support North American Vascular 19th International Vascular $10,000.00 Biology Organization Biology Meeting Inc. North Shore Community Volunteer Match $1,000.00 Health Inc. Northeast Business Congress Sponsorships $5,000.00 group on Health Northeastern University Allston Brighton College $2,000.00 Scholarship Northwest Animal Rights Volunteer Match $1,000.00 Network Northwest Animal Rights Volunteer Match $1,000.00 Network Norton Healthcare Moonlight & Moonshine Gala $5,000.00 Foundation, Inc. Norton Healthcare Neuroscience Expo $10,000.00 Foundation, Inc. Norton Healthcare 1-N-3 Gala $5,000.00 Foundation, Inc. Operation Warm Inc. Boston Warmth in Winter $18,000.00 OptumHealth Education Congress Sponsorships $7,500.00 Oregon Health & Science On the Horizon: Updates in $9,930.00 University Foundation Multiple Sclerosis Pan Massachusetts Volunteer Match $11,000.00 Challenge Pan Massachusetts Volunteer Match $11,000.00 Challenge Patient Access Network Patient Assistance Program $100,000.00 Foundation for Thyroid Cancer Patient Access Network Patient Assistance Program $100,000.00 Foundation for Thyroid Cancer Patient Access Network Patient Assistance Fund for $100,000.00 Foundation Thyroid Cancer Patient Access Network Patient Assistance Program $50,000.00 Foundation for Thyroid Cancer Patient Access Network Patient Assistance Program $50,000.00 Foundation for Homozygous Familial Hypercholesterolemia Patient Access Network Patient Assistance Program $125,000.00 Foundation for Homozygous Familial Hypercholesterolemia Patient Services Inc. Patient Assistance Program $4,440,000.00 for Fabry, Pompe, MPS1, and Gaucher Disease Patient Services Inc. Patient Assistance Program $2,000,000.00 Patient Services Inc. Patient Assistance Program $6,500,000.00 Peer Health Exchange Peer Health Exchange: $5,000.00 Inc. Empowering Boston Youth to Make Healthy Decisions Perkins School for the Perkins eLearning: Enhancing $20,000.00 Blind Accessible Science Education Phillips Brooks House Community Program $5,000.00 Association Incorporated Phoenix Children's MPS patient meeting $1,200.00 Hospital Foundation Portland VA Research PDX Patient Workshops $3,150.00 Foundation Inc. President and Fellows Community Program $20,000.00 of Harvard College President and Fellows Patient Assistance Program $50,000.00 of Harvard College Pro Player Foundation Flavors of Austin $5,000.00 Pro Player Foundation Flavors of Austin $5,000.00 Project Eden Inc. Volunteer Match $1,000.00 Project Just Because, 211 Domestic Abuse/Emergency $10,000.00 Inc. Program & Keep A Family Warm Program Race to Erase MS Race to Erase MS--MS Forum $10,000.00 Race to Erase MS 23rd Annual Race to Erase MS $50,000.00 Read to a Child, Inc. Community Program $5,000.00 Read to a Child, Inc. Community Program $2,500.00 Resolve Community Volunteer Match $1,000.00 Counseling Center, Inc. Restore Volunteer Match $1,000.00 Rocky Mountain Multiple KADEP (King Adult Day $5,000.00 Sclerosis Center Enrichment Program) Annual Winter Community Gathering Rocky Mountain Multiple Rocky Mountain MS Center $10,000.00 Sclerosis Center Annual Gala Rocky Mountain Multiple MS4MS Event $5,000.00 Sclerosis Center Rocky Mountain Multiple KADEP Annual Holiday $5,000.00 Sclerosis Center Celebration Rocky Mountain Multiple Webinar Series $5,000.00 Sclerosis Center Room to Grow Community Program $5,000.00 Runkle School Extended Volunteer Match $1,000.00 Day Program Inc. S S Cosmas & Damian Community Program $2,500.00 Society Inc. Saint Francis Hospital International Symposium: The $50,000.00 and Medical Center Multiple Sclerosis Brain-- Foundation Bridging the Gap Salute the Ribbon Meet, Greet n' Eat Luncheon $1,000.00 Incorporated ``Opening Doors for Health Care Access to Cancer Care'' Samaritans Inc. Community Program $25,000.00 Science Club For Girls Community Program $10,000.00 Inc. Science Club For Girls Catalyst Awards $10,000.00 Inc. Science From Scientists STEM enrichment program for $25,000.00 Inc. Boston Public Schools Science From Scientists In-School Module-Based (ISMB) $20,000.00 Inc. STEM enrichment program Science From Scientists 70th Annual Boston Citywide $10,000.00 Inc. Science Fair Sharp Rees-Stealy Congress Sponsorships $5,000.00 Medical Group Sharp Healthcare Society for Inherited North American Metabolic $20,000.00 Metabolic Disorders Academy Society of Nuclear SNMMI Patient Education Day $5,000.00 Medicine and Molecular Imaging Special Olympics Bio-Ball $2,500.00 Massachusetts Inc. St. Francis House Community Program $10,000.00 Stop Hunger Now, Inc. Volunteer Match $2,944.08 Strongwater Farm Riding group for individuals $7,500.00 Therapeutic Equestrian living with MS Center Temple Beth Sholom [The Patient Education and $6,200.00 Tribe] Awareness Program Temple University Allston Brighton College $2,000.00 Scholarship The Boston Home, Inc. Volunteer Match $1,000.00 The Boston Home, Inc. The Boston Home iPad InstaAid $12,000.00 Program Expansion The Boston Home, Inc. The Boston Home Arts Program $10,000.00 The Boston Home, Inc. The Boston Home B.Fit $18,000.00 Wellness Program The Boston Home, Inc. The Boston Home Resident $10,000.00 Family Picnic The Boston Home, Inc. Finding Your Voice $5,000.00 The Community Art Teen Media Program $15,000.00 Center The Discovery Museums Genzyme Discovery Science $15,000.00 The Discovery Museums Discovery Science Program $15,000.00 The Forsyth Institute Community Program $10,000.00 The Greater Boston Food Volunteer Match $2,000.00 Bank Inc. The Greater Boston Food General Operating Support $10,000.00 Bank Inc. The Greater Boston Food Volunteer Match $1,000.00 Bank Inc. The Jewish Community Our Heritage and Our Health-- $1,250.00 Center of Greater Ashkenazi Jewish Genetic Kansas City Disease and the Founder Effect The Jewish P.O.C.E.T. Greater Chicago Jewish $3,240.00 Festival The Leukemia & Lymphoma Light The Night Walk $6,500.00 Society Inc. The Life Sciences Leadership Mid-Term Funding $50,000.00 Foundation for Educational Programs The McCourt Foundation Tour de South Shore $10,000.00 The McCourt Foundation McCourt Gala $20,000.00 The McCourt Foundation McCourt Foundation MS $20,000.00 Educational Update The Oak Clinic Oak Clinic Acorn Run $3,500.00 The Oak Clinic Diamond Run $5,000.00 The Posse Foundation Community Program $25,000.00 The Possible Project The Possible Project's $10,000.00 Powering Possibilities Annual Gala The Salvation Army Volunteer Match $2,000.00 Thompson Island Outward Community Program $10,000.00 Bound Education Center Inc. Thompson Island Outward Islands Expedition Gala $5,000.00 Bound Education Center Inc. Thompson Island Outward Thompson Island 4K Trail Run $5,000.00 Bound Education Center Inc. ThyCa: Thyroid Cancer Patient Education and $15,000.00 Survivors' Awareness Program Association, Inc. ThyCa: Thyroid Cancer 19th International Thyroid $35,000.00 Survivors' Cancer Survivors' Conference Association, Inc. Tisch Multiple Tisch MS Research Center $15,000.00 Sclerosis Research Newsletter Center of New York, Inc. Tisch Multiple Future Without MS Gala $5,000.00 Sclerosis Research Center of New York, Inc. Tisch Multiple Future Without MS Gala $15,000.00 Sclerosis Research Center of New York, Inc. Tisch Multiple Tisch MS Research Center 19th $25,000.00 Sclerosis Research Annual MS Patient Symposium Center of New York, Inc. Triangle, Inc. Volunteer Match $1,000.00 Triangle, Inc. Triangle's 45th Annual Spring $5,000.00 Gala Tri-State Multiple Evansville Autumn Walk $2,500.00 Sclerosis Association Tri-State Multiple Owensboro Autumn Walk $2,500.00 Sclerosis Association Tri-State Multiple Evening of Excellence $2,000.00 Sclerosis Association Tri-State Multiple Tri-State Multiple Sclerosis $4,500.00 Sclerosis Association Association Autumn Walks Tutoring Plus of STEAM Enrichment Programs $7,500.00 Cambridge, Inc. Tutoring Plus of Community Program $5,000.00 Cambridge, Inc. U C San Diego UCSD Regional MS Expositions $50,000.00 Foundation United Network for Congress Sponsorship $7,800.00 Organ Sharing United Pompe Foundation Duke Late Onset Pompe Patient $19,000.00 Meeting United Pompe Foundation Pompe Patient Meeting $19,000.00 United Pompe Foundation General Operating Support $50,000.00 United Rheumatology Congress Sponsorship $60,000.00 United Way of Tri Volunteer Match $1,000.00 County Inc. United Way of Tri Volunteer Match $1,000.00 County Inc. United Way of Tri Volunteer Match $1,000.00 County Inc. United Way of Tri Volunteer Match $2,000.00 County Inc. University of Student Success Program, $200,000.00 Massachusetts UMass Boston, College of Foundation Inc. Science and Mathematics University of Massachusetts STEM Summit $5,000.00 Massachusetts Foundation Inc. University of Southern Allston Brighton College $4,000.00 California Scholarship Visiting Nurse Heroes in Health Care Gala $10,000.00 Association of Boston & Affiliates VNA Care Hospice Inc. Community Program $5,000.00 VNA Care Hospice Inc. Community Program $5,000.00 Wentworth Institute of Allston Brighton College $2,000.00 Technology Scholarship West End House Boys and Volunteer Match $1,000.00 Girls Club West End House Boys and Community Program $25,000.00 Girls Club West End House Boys and Community Program $25,000.00 Girls Club WGBH Pledge Night Sponsorship $12,000.00 Whitehead Institute for Whitehead Institute's CampBio $10,000.00 Biomedical Research Program Women's Lunch Place Meals Program $35,000.00 Women's Lunch Place General Operating Support $10,000.00 Women's Lunch Place Community Program $10,000.00 World Unity Inc. Volunteer Match $1,000.00 WriteBoston Community Program $10,000.00 Wylder Nation Patient Education and $15,000.00 Foundation Awareness Program Wylder Nation 3rd Annual Living Like a $15,000.00 Foundation Warrior Gala YMCA of Greater Boston Oak Square YMCA--Summer Day $15,000.00 Camp Scholarships ziMS Foundation ziMS STRIKE DOWN MS Event $5,000.00 Sponsorships and Charitable Donations 1st Jan 2017-31st Dec 2017 Sanofi US and its affiliate Genzyme Corporation are committed to supporting sponsorships for specific activities and initiatives of healthcare organizations and institutions, independent medical or professional societies, trade organizations and organized patient groups to improve patient care and provide information to the medical and/or patient communities. The goal of our charitable giving approach is to fund general operational support for patient/disease organizations, or program support for community-based organizations. Sanofi US and Genzyme Corporation are part of the Sanofi Group, a global pharmaceutical company. Applicant names are provided by the requestor. If applicants apply as a group for a single activity; all applicants may be not be identified above. ``Funding Amount'' is the amount that the Company funded during 2017 identified above. ``Funding Amount'' does not include funds that may have been provided by other affiliated Sanofi Company Entities (e.g., Sanofi Pasteur). Recipient Name(s) Activity Title Funding Amount American Academy of Congress Sponsorship $35,317.50 Neurology Academy of Managed Care Congress Sponsorship $1,000.00 Pharmacy A New Jersey Nonprofit Corporation Academy of Managed Care Congress Sponsorship $26,500.00 Pharmacy A New Jersey Nonprofit Corporation Accelerated Cure 2017 Leadership Summit $15,000.00 Project Acid Maltase Deficiency Annual Fundraiser $3,000.00 Association Inc. Acid Maltase Deficiency General Operating Support $50,000.00 Association, Inc. Alabama Kidney Patient Education Conferences $2,500.00 Foundation Allergy & Asthma Understanding Atopic $75,000.00 Network Mothers of Dermatitis Guide Asthmatics, Inc. Allergy & Asthma Patient Activation $200,000.00 Network Mothers of Measurement Study Asthmatics, Inc. Allergy & Asthma GlobalSkin Conference $3,000.00 Network Mothers of Asthmatics, Inc. Allergy & Asthma Severe Asthma Awareness $150,000.00 Network Mothers of Campaign Asthmatics, Inc. Allergy & Asthma Project Access Initiative $25,000.00 Network Mothers of Asthmatics, Inc. Allergy & Asthma Allergy & Asthma Awareness $25,000.00 Network Mothers of Day Asthmatics, Inc. Allergy & Asthma Allergy & Asthma Network $25,000.00 Network Mothers of Corporate Council 2017 Asthmatics, Inc. Alliance for Patient 2018 Membership $100,000.00 Access Allston Village Main Taste of Allston Event $1,000.00 Streets, Inc. American Academy of Patient AccessDerm Program $250,000.00 Dermatology American Academy of President's Summit on $5,000.00 Dermatology Diversity in Dermatology American Academy of Congress Sponsorship $17,800.00 Neurology American Academy of Congress Sponsorship $432,935.00 Neurology American Academy of Emerging Leaders Program $20,000.00 Neurology Institute American Academy of Women Leading in Neurology $20,000.00 Neurology Institute Program American Academy of Clinical Research Training $50,000.00 Neurology Institute Scholarship in Multiple Sclerosis American Academy of Palatucci Advocacy Leadership $50,000.00 Neurology Institute Forum American Academy of Residents Scholarship Fund $20,000.00 Neurology Institute American Academy of Fellows Scholarship Fund $20,000.00 Neurology Institute American Academy of Brain Health Fair $10,000.00 Neurology Institute American Academy of Neurology Annual Meeting 2017 $208,632.90 Neurology Institute American Academy of Transforming Leaders Program $20,000.00 Neurology Institute American Association AAAS 2017 Annual Meeting-- $25,000.00 For The Advancement of Family Science Days Science American Association of Congress Sponsorship $4,300.00 Clinical Endocrinologists American Association of Congress Sponsorship $18,500.00 Endocrine Surgeons American Association of Congress Sponsorship $67,600.00 Neuromuscular & Electrodiagnostic Medicine American Brain Membership $20,000.00 Coalition American Cancer Society 25th Making Strides Against $1,000.00 Breast Cancer Walk American Cancer Society Bicycles Battling Cancer 2017 $11,000.00 American Cancer Society Bicycles Battling Cancer 2016 $11,000.00 American Cancer Society 10th Annual ACS CAN New $10,000.00 Cancer Action Network England Research Breakfast American College of Shared Decision Making $125,000.00 Allergy, Asthma & Toolkit for Severe Atopic Immunology Dermatitis American College of Severe Pediatric Asthma $60,000.00 Allergy, Asthma & Shared Decision Making Immunology Toolkit American College of Shared Decision Making $125,000.00 Allergy, Asthma & Toolkit for Severe Pediatric Immunology Asthma American College of Practice Management Center $240,000.00 Allergy, Asthma & Immunology American College of Patient Education Brochure $31,000.00 Allergy, Asthma & Immunology American College of Atopic Dermatitis Yardstick $145,000.00 Allergy, Asthma & Educational Manuscript Immunology American College of Membership $60,000.00 Chest Physicians American College of Congress Sponsorship $2,000.00 Rheumatology American Lung Membership $20,000.00 Association American Lung Asthma Care Coverage Project $75,000.00 Association American Optometric Congress Sponsorship $3,150.00 Association American Red Cross of Women Who Care Leadership $5,000.00 Massachusetts Breakfast American Society of ASCO Annual Meeting $118,000.00 Clinical Oncology American Society of 59th Annual ASH Convention $224,300.00 Hematology American Society of Congress Sponsorship $56,600.00 Hematology American Society of Congress Sponsorship $3,300.00 Human Genetics American Society of Congress Sponsorship $35,000.00 Nephrology American Society of Congress Sponsorship $20,950.00 Nephrology American Society of Congress Sponsorship $40,000.00 Nephrology American Society of Congress Sponsorship $35,000.00 Transplant Surgeons American Society of Congress Sponsorship $6,000.00 Transplant Surgeons American Society of Congress Sponsorship $35,000.00 Transplantation American Society of Congress Sponsorship $35,000.00 Transplantation American Thoracic Corporate Membership Program $50,000.00 Society American Thyroid Congress Sponsorship $11,950.00 Association American Thyroid Congress Sponsorship $18,000.00 Association American Transplant Congress Sponsorship $45,000.00 Congress Americas Committee for Congress Sponsorship $15,000.00 Treatment and Research in Multiple Sclerosis, Inc. ANERA (American Near Annual Dinner $5,000.00 East Refugee Aid) Ann & Robert H. Lurie MPS Patient and Family Day $2,500.00 Children's Hospital of Chicago Arizona Myeloma Network Cancer Patient & Caregivers $3,250.00 Outreach & Seminar Series Arthritis Foundation-- 37th Annual Silver Ball Gala $1,250.00 St. Louis, MO Arthritis Foundation-- Arthritis Industry Forum $25,000.00 Atlanta, GA Arthritis Foundation-- Casino Night Gala $2,500.00 St. Paul, MN Arthritis Foundation-- Patient Engagement Program $25,000.00 Atlanta, GA Arthritis Foundation-- Taste of the Town Gala $5,000.00 Hawaii Chapter Arthritis Foundation-- Freedom of Movement Gala $5,000.00 Chicago, IL Arthritis Foundation-- Houston Bone Bash Gala $10,000.00 Houston, TX Arthritis Foundation-- PREOP Training and Engagement $250,000.00 Atlanta, GA Initiative Arthritis Foundation-- Walk to Cure Arthritis and $250,000.00 Atlanta, GA Jingle Bell Run Arthritis Foundation-- Walk to Cure Arthritis $3,500.00 Green Bay, WI Arthritis Foundation-- Walk to Cure Arthritis $5,000.00 Sacramento, CA Arthritis Foundation-- Walk to Cure Arthritis $2,500.00 Irvine, CA Arthritis Foundation-- Walk to Cure Arthritis $1,000.00 St. Paul, MN Arthritis Foundation-- Ambassador Program $125,000.00 Atlanta, GA Arthritis Foundation-- Advocacy Summit $25,000.00 Atlanta, GA Arthritis Foundation-- Walk to Cure Arthritis $5,000.00 Boston, MA Arthritis Foundation-- Walk to Cure Arthritis $5,000.00 Los Angeles, CA Arthritis Foundation-- Patient Voice Accumulator $50,000.00 Atlanta, GA Project Arthritis Foundation-- 51st Annual Knowles Lecture $7,500.00 Northern California Arthritis Foundation-- Walk to Cure Arthritis $1,000.00 Hawaii Chapter Arthritis Foundation-- Walk to Cure Arthritis $2,500.00 Chicago, IL Arthritis Foundation-- Walk to Cure Arthritis $2,500.00 New England Chapter Arthritis Foundation-- Walk to Cure Arthritis $2,500.00 New England Chapter Arthritis Foundation-- Evening of Honors Event $5,000.00 New Jersey Chapter ASCO Congress Sponsorship $5,495.00 Asembia Specialty Asembia Specialty Pharmacy $20,000.00 Pharmacy Summit LLC Summit Assistance Fund Inc Patient Assistance Program $10,000,000.00 for MS Association For Annual Conference $7,000.00 Glycogen Storage Disease Association of 41st Annual APHON Conference $6,850.00 Pediatric Hematology/ Oncology Nurses Association of VA 13th Annual AVAHO Meeting $10,000.00 Hematology/Oncology Asthma and Allergy Strengthening the Asthma $200,000.00 Foundation of America Community Asthma and Allergy Asthma Capitals Report $125,000.00 Foundation of America Asthma and Allergy Supporting Patients and $110,000.00 Foundation of America Families Program Asthma and Allergy Research Project $200,000.00 Foundation of America Asthma and Allergy Research Project $120,000.00 Foundation of America Barbara Ann Karmanos Seventh Annual Prostate $7,500.00 Cancer Institute Cancer Advocacy Symposium Bendcare National Meeting $10,310.00 Bendcare Educational Conferences $92,790.00 Berkshire Resource People Living with MS that $4,000.00 Project have Impaired Vision Program Berkshire Resource Functional Ability Skills for $3,500.00 Project Everyday Living With Multiple Sclerosis Berkshire Resource 9th Annual Gala ``Let's Kiss $5,000.00 Project MS Goodbye'' Berkshire Resource Coping With The Emotional $4,000.00 Project Aspects of MS Program Big Brothers Big MySTEM Program $15,000.00 Sisters of Central Mass Metrowest Inc. Biomedical Science Evening of Hope 2017 $100,000.00 Careers Program Biomedical Science Hope Scholarship 2017-2018 $7,500.00 Careers Program Blue Cross Blue Shield Blues National Summit $15,975.00 Association Boston Business Boston Business Journal $5,500.00 Journal, Inc. Corporate Citizenship Awards Boston Health Care For Charitable Contribution--Life $35,000.00 The Homeless Program, Essentials for Homeless Inc. Patients Boston Partners in Power Lunch Program $6,000.00 Education, Inc. Boston Private Industry 2017 Corporate Contributions $15,000.00 Council Campaign Boston Private Industry Volunteer Match $1,000.00 Council Bottom Line Boston STEM Success Program $15,000.00 Boys & Girls Clubs of Fall Flashback Festival $5,000.00 Medford and Somerville Inc. Boys and Girls Clubs of Volunteer Match $2,000.00 MetroWest Boys and Girls Clubs of Volunteer Match $1,000.00 MetroWest Boys and Girls Clubs of Bids for Kids Auction & Gala $10,000.00 MetroWest Boys and Girls Clubs of Membership $25,000.00 MetroWest Boys and Girls Clubs of Volunteer Match $2,000.00 MetroWest BPE Boston Teacher Residency: $15,000.00 Innovative STEM Educators Program Breakthrough Greater Full STEAM Ahead Program $15,000.00 Boston Breakthrough Greater Full STEAM Ahead Program $10,000.00 Boston California Life CLSA Life Sciences Academy $8,000.00 Sciences Association California rheumatology Annual Meeting $50,000.00 Alliance Cambridge Chamber of Lead Sponsorship $7,500.00 Commerce Cambridge Health Volunteer Match $1,000.00 Alliance Foundation, Inc. Cambridge School Volunteer Match $1,000.00 Volunteers, Inc. Cambridgeport 2017 Summer Programs for $5,000.00 Neighborhood Magazine Beach Park Support Association, Inc. Can Do Multiple 2018 SKI for MS $40,000.00 Sclerosis Can Do Multiple 2017 MS Global $10,000.00 Sclerosis Can Do Multiple 2017 TAKE CHARGE Program $40,000.00 Sclerosis Can Do Multiple 8th Annual Can Do Day $10,000.00 Sclerosis Can Do Multiple 2017 CAN DO Programs $50,000.00 Sclerosis Can Do Multiple Can Do On Demand Program $60,000.00 Sclerosis Can Do Multiple 2017 TAKE CHARGE and $16,500.00 Sclerosis JUMPSTART Programs Can Do Multiple 2017 JUMPSTART Programs $80,000.00 Sclerosis Can Do Multiple 2017 Ski for MS $30,000.00 Sclerosis Can Do Multiple 2017 Online Programs $45,000.00 Sclerosis Can Do Multiple Can Do MS eNews: Your Best $5,000.00 Sclerosis Life Update Case Management Society Annual Corporate Partnership $5,500.00 of America Case Management Society CMSA 2017 Conference $14,000.00 of America Case Management Society CMSA 27th Annual Conference & $1,725.00 of America Expo Case Management Society Focus on the Future--Keeping $1,050.00 of New England a Keen Eye on Tomorrow Program Case Management Society Corporate Sponsorship $1,250.00 of New England Case Management Society Case Management Society of $1,000.00 of New England New England Conference Charles River Community Mom and Baby Program $15,000.00 Health CheckOrphan Rare Disease Page Sponsorship $40,000.00 Chicago Rheumatism Congress Sponsorship $4,500.00 Society Childrens Gaucher Research Grant $75,000.00 Research Fund Children's Hospital Milagros para Ninos 2017 Gala $5,000.00 Corporation Chronic Disease Fund, Patient Assistance Program $350,000.00 Inc. DBA Good Days from CDF Cincinnati Children's Congress Sponsorship $10,000.00 Hospital Medical Center Cleveland Clinic Congress Sponsorship $15,000.00 Educational Institute Cleveland Clinic 5th Annual Basic & Clinical $3,500.00 Educational Institute Immunology for the Busy Clinician Clevleand Clinic Scott Hamilton and Friends $5,000.00 Ice Show and Gala Coalition of State CSRO State Society Key $37,500.00 Rheumatology Legislator Education Program Organizations Coalition of State Coalition of State $100,000.00 Rheumatology Rheumatology Organizations Organizations Support Community Boating, Inc. Universal Access Program 2017 $15,000.00 Community Farms Fresh Food Access $15,000.00 Outreach Community Farms Volunteer Match $1,000.00 Outreach Community Oncology Congress Sponsorship $33,000.00 Alliance Community Servings, 25th Anniversary Pie in the $10,000.00 Inc. Sky Fundraiser Consortium of Multiple North American Registry for $200,000.00 Sclerosis Centers Care and Research in Multiple Sclerosis Support Consortium of Multiple 2017 CMSC Annual Meeting $100,000.00 Sclerosis Centers Courageous Parents Empowering parents and $26,250.00 Network caregivers of children with MPS, Gaucher, Nieman-Pick Cradles to Crayons Ready for School Program $20,000.00 Support Cradles to Crayons Volunteer Match $2,000.00 Cure GM1 Incorporated TORCH Award $5,000.00 Cure Sanfilippo TORCH Award $5,000.00 Foundation Cystic Fibrosis Uncork the Cure $15,000.00 Foundation Cystic Fibrosis Massachusetts CF Cycle for $4,000.00 Foundation Life Fundraiser DEAF, Inc.-- Deaf-Accessible Medical Case $10,000.00 Developmental Management and Access to Evaluation and Health Program Adjustment Facilities, Inc. Department of Congress Sponsorship $5,878.75 Pediatrics, Tufts Medical Center Dimock Community Volunteer Match $1,000.00 Foundation Inc. Dimock Community 30th Anniversary Steppin' Out $100,000.00 Foundation Inc. for The Dimock Center DPC Education Center Fabry Disease Education $27,500.00 Program Eastern Allergy Congress Sponsorship $39,000.00 Conference Emerald Necklace 14th Anniversary Party in the $6,500.00 Conservancy, Inc. Park Emory University JScreen Jewish Genetic $216,089.00 Disease Education Initiative Endocrine Society Congress Sponsorship $24,500.00 EveryLife Foundation 2017 RareVoice Awards $30,000.00 for Rare Diseases EveryLife Foundation Emerging Technologies for $15,000.00 for Rare Diseases Rare Diseases: Clinical & Regulatory Case Studies and Approval Pathways EveryLife Foundation Rare on the Road Leadership $30,000.00 for Rare Diseases Tour EveryLife Foundation TORCH Award Donations $5,000.00 for Rare Diseases Fabry Support & FSIG Fun Run/Walk $1,500.00 Information Group Fabry Support & General Operating Support $100,000.00 Information Group Fabry Support & FSIG Annual Family Conference $1,000.00 Information Group Fabry Support & 2017 FSIG Expert Fabry $50,000.00 Information Group Conference Family Promise Fundraising Event $2,500.00 Metrowest, Inc. Florida Society of Congress Sponsorship $35,000.00 Rheumatology Food For Free A Nutrition Program for $5,000.00 Committee, Inc. Seniors and People with Disabilities Foundation of the Newsletter Support $6,500.00 Consortium of MS Centers Foundation of the Annual Meeting $5,450.00 Consortium of MS Centers Foundation of the Research Grant $42,000.00 Consortium of MS Centers Foundation of the Multiple Sclerosis Workforce $32,000.00 Consortium of MS of the Future 2018:Medical Centers Student Research Scholarships Foundation of the NARCOMS NOW Patient Quarterly $33,583.00 Consortium of MS Magazine Centers Foundation of the Congress Sponsorship $432,000.00 Consortium of MS Centers Framingham Townwide Pto Volunteer Match $1,000.00 Council Franciscan Hospital For Adaptive Sports Program $15,000.00 Children, Inc. Friends of Children Celebrating Fatherhood Brunch $2,500.00 Trust Fund, Inc. Friends of Resiliency Resiliency's Academic Support $10,000.00 For Life, Inc. Fundacion de Esclerosis Hurricane Relief $3,334.00 Multiple de Puerto Rico Generation Citizen, Massachusetts Spring 2017 $6,000.00 Inc. Civics Day Genetic Alliance, Inc. 30th Anniversary Conference $30,000.00 and Celebration Genetic Alliance, Inc. 30th Anniversary Conference $30,000.00 and Celebration Genetic Disease Fabry disease (dbFGP) Support $100,000.00 Foundation Georgia Chapter of the Georgia AAP: Pediatrics on $5,000.00 American Academy of the Parkway Pediatrics Georgia Society of Congress Sponsorship $2,000.00 Rheumatology Georgia Society of Congress Sponsorship $8,000.00 Rheumatology Girl Scouts of Eastern Girls Building Self-eSTeEM $15,000.00 Massachusetts Inc. Program Global Academy For Congress Sponsorship $55,000.00 Medical Education, Inc. Global Alliance for Membership $50,000.00 Patient Access Global Genes RARE Tribute to Champions of $25,000.00 Hope Global Genes RARE Patient Advocacy Summit $25,000.00 Global Genes Membership $25,000.00 Greater Boston Chamber 2017 Annual Meeting $10,000.00 of Commerce Habitat For Humanity High Heels and Hard Hats $10,000.00 Metrowest--Greater Auction and Gala Worcester, Inc. Habitat For Humanity Home Renovation Build Support $20,000.00 Metrowest--Greater Worcester, Inc. Hadassah Greater Our Heritage and Our Health-- $900.00 Detroit Jewish Genetic Disorders and Founder Effect Program Health Care For All, Public Education Campaign $15,000.00 Inc. Health Literacy Media MTC Educational Program $50,000.00 Hearts & Noses Hospital Ongoing Bedside Hospital $15,000.00 Clown Troupe, Inc. Clown Visits Program Hematology Oncology Congress Sponsorship $7,500.00 Managers of New York, Inc. Holy Name Health Care 2017 MS Awards Reception $2,500.00 MS Center Holy Name Medical 20th Annual Spring Fling to $2,500.00 Center Benefit MS Hope and Comfort, Inc. Hope and Comfort Program $5,000.00 Support Horizons for Homeless 19th Annual Women's Breakfast $5,000.00 Children Houston Food Bank Volunteer Match $1,000.00 Imedex, LLC Congress Sponsorship $94,778.35 International Institute Healthcare Navigation for $15,000.00 of New England Refugees Program International Institute 2017 Golden Door Award Gala $10,000.00 of New England International Institute Transport Costs for Bicycles $100.00 of New England for Refugee Families International 20th Anniversary IOMSN Dinner $30,000.00 Organization of Multiple Sclerosis Nurses International 2017 MS Perspectives Digital $40,000.00 Organization of Magazine Multiple Sclerosis Nurses International Society 5th Glycoproteinoses $16,650.00 For Mannosidosis & International Conference Related Disease Inc. Jewish Genetic Disease General Operating Support $5,000.00 Consortium Knect365 US, Inc. Battle of the Biotech Bands $5,000.00 Fundraiser Kometa Serbian Volunteer Match $1,000.00 Childrens Program Inc. Life Science Cares, Life Science Cares Impact $10,000.00 Inc. Breakfast Light of Life Light of Life Foundation 2017 $40,000.00 Foundation Activities Little Brothers/Friends Medical Escort/Transportation $7,500.00 of the Elderly Program Little Miss Hannah Vegas Cares About Rare Kids $5,000.00 Foundation 5K Little Miss Hannah Vegas Cares About Rare Kids $2,500.00 Foundation 5K LUGPA LUGPA Annual Meeting $10,000.00 Lycee International De ISB Benefit Gala $8,000.00 Boston International School of Boston Inc. MagellanRx Management Congress Sponsorship $7,500.00 March of Dimes Volunteer Match $2,000.00 Foundation March of Dimes Boston March for Babies $25,000.00 Foundation Fundraiser March of Dimes Volunteer Match $1,000.00 Foundation Margaret Fuller Youth Development Programs $15,000.00 Neighborhood House Mass Insight Education STEM and English Program $15,000.00 and Research Institute Inc. Massachusetts Bay STEM Mentor Program $40,000.00 Community College Foundation Massachusetts Patient Advocacy Summit $10,000.00 Biotechnology Council Massachusetts Congress Sponsorship $25,000.00 Biotechnology Council Massachusetts MassBio Annual Meeting $10,000.00 Biotechnology Council Massachusetts Rare Disease Day 2017 $1,000.00 Biotechnology Council Massachusetts 2017 Champions for $3,500.00 Biotechnology Biotechnology Awards Education Foundation, Inc. Massachusetts BioTeach Program $50,000.00 Biotechnology Education Foundation, Inc. Massachusetts Life Sciences Workforce 2017, $3,500.00 Biotechnology 2nd Annual Conference Education Foundation, Inc. Massachusetts College Sanofi Genzyme Biotchnology $7,000.00 of Pharmacy and Health College Scholarship Sciences Massachusetts State Advancing Science & Health $50,000.00 Science and Education Programs Engineering Fair, Inc. Mayo Clinic Congress Sponsorship $2,000.00 MedImpact Healthcare Congress Sponsorship $8,000.00 Systems, Inc. MetroWest Chamber of Board of Directors Luncheon $250.00 Commerce Metrowest Free Medical Access to Women's Health Care $15,000.00 Program Inc. for the Uninsured Mid America MS Eat Bid Laugh 6 Event $10,000.00 Achievement Center Mid America MS Race to Nowhere 19 $5,000.00 Achievement Center Milwaukee Synagogue for Education Program $5,000.00 Russian Jews: Congregation Moshiach Now Inc. Milwaukee Synagogue for Education Program $5,000.00 Russian Jews: Congregation Moshiach Now Inc. MS Bright Spots of Hope MS Evening of Hope $2,500.00 MS Cure Fund Patient Education Programs $25,000.00 MS Cure Fund Late Summer Education $25,000.00 Programs MS Cure Fund Lifestyle Management Programs $15,000.00 Spring 2017 MS Cure Fund 2017 Spring MS Health Fair $1,500.00 MS HOPE FOR A CURE INC. 2017 MS Hope Day $10,000.00 MS Views And News Inc. MS Neuro TV $35,000.00 MS Views And News Inc. Living Beyond MS--Effective $20,000.00 Communication with Your Healthcare Team MS Views And News Inc. The Compass To Care Program $73,550.00 MS Views And News Inc. 2017 Display Sponsorship $10,000.00 request MS Views And News Inc. Educational Programs $23,825.00 MS Views And News Inc. Educational Programs $25,000.00 MS Views And News Inc. 2nd Annual Champions Tackling $10,000.00 MS Awards Dinner Gala MS Views And News Inc. MS Views and News 2017 $1,000.00 Bowlathon Multiple Myeloma Cure Defeat Multiple Myeloma run/ $5,000.00 Seeker Society walk Multiple Sclerosis Navigating MS: Optimizing $73,125.00 Association of America Multiple Sclerosis MSAA MRI Access Fund $125,000.00 Association of America Multiple Sclerosis MSAA Improving Lives Benefit $2,500.00 Association of America 2017 Multiple Sclerosis Educational Programs $60,000.00 Association of America Multiple Sclerosis Understanding MS Progression $39,000.00 Association of America Multiple Sclerosis MS Fest $10,000.00 Center of Georgia Multiple Sclerosis Health, Hope & Hops $7,000.00 Center of Georgia Multiple Sclerosis MS Focus' EmpowerSource $35,000.00 Foundation Newsleter Multiple Sclerosis Mind & Mobility $5,000.00 Foundation Multiple Sclerosis Homecare Assistance Grant $20,000.00 Foundation Program Multiple Sclerosis Assistive Technology Program $30,000.00 Foundation Multiple Sclerosis 2017 National MS Education $30,000.00 Foundation and Awareness Month Multiple Sclerosis 30th Anniversary Gala $5,000.00 Foundation ``Bourbon & Blues'' Multiple Sclerosis 2017 Mission Steps Walks & MS $8,000.00 Resources of Central Awareness Days New York, Inc. Multiple Sclerosis MS Awareness Expo $1,000.00 Society of Colorado Springs, Inc. Muscular Dystrophy Muscle Walk $1,000.00 Association--Pittsburg h, PA Muscular Dystrophy Muscle Walk $1,000.00 Association--Denver, CO Muscular Dystrophy 5th Annual Muscle Summit $6,000.00 Association--Harrisbur g, PA Muscular Dystrophy MDA Muscle Summit $8,000.00 Association--Broomall, PA Muscular Dystrophy Muscle Walk $1,000.00 Association--Shrevepor t, LA Muscular Dystrophy Muscle Walk $1,000.00 Association--Deerfield Beach, FL Muscular Dystrophy Muscle Walk $1,000.00 Association--Tallahass ee, FL Muscular Dystrophy Muscle Walk $1,000.00 Association--Grand Rapids, MI Muscular Dystrophy Muscle Walk $1,000.00 Association--Fort Wayne, IN Muscular Dystrophy Muscle Walk $1,000.00 Association--Metairie, LA Muscular Dystrophy Muscle Walk $1,000.00 Association--Deerfield Beach, FL Muscular Dystrophy Muscle Walk $1,000.00 Association--Los Angeles, CA Muscular Dystrophy Muscle Walk $1,000.00 Association--Shrevepor t, LA Muscular Dystrophy Muscle Walk $1,000.00 Association--Harrisbur g, PA Muscular Dystrophy Muscle Walk $1,000.00 Association--Allentown , PA Muscular Dystrophy Muscle Walk $2,000.00 Association--Urbana, IL Muscular Dystrophy Muscle Walk $1,000.00 Association--Billings, MT Muscular Dystrophy Muscle Walk $1,000.00 Association--San Diego, CA Muscular Dystrophy Muscle Walk $1,000.00 Association--Cincinnat i, OH Muscular Dystrophy Muscle Walk $1,000.00 Association--Portland, MA Muscular Dystrophy Muscle Walk $1,000.00 Association--Spokane, WA Muscular Dystrophy Muscle Walk $1,000.00 Association--Salt Lake City, UT Muscular Dystrophy Muscle Walk $1,000.00 Association--Louisvill e, KY Muscular Dystrophy Muscle Walk $1,000.00 Association--Wilmingto n, NC Muscular Dystrophy Muscle Walk $1,000.00 Association--Worthingt on, OH Muscular Dystrophy Muscle Walk $1,000.00 Association--Dallas, TX Muscular Dystrophy Muscle Walk $1,000.00 Association--Albany, NY Muscular Dystrophy Muscle Walk $1,000.00 Association--Chicago, IL Muscular Dystrophy Muscle Walk $1,000.00 Association--Greensbor o, NC Muscular Dystrophy Muscle Walk $1,000.00 Association--Columbus, OH Muscular Dystrophy Muscle Walk $1,000.00 Association--Albany, NY Muscular Dystrophy Muscle Walk $1,000.00 Association--Cincinnat i, OH Muscular Dystrophy Muscle Walk $1,000.00 Association--Portland, OR Muscular Dystrophy Muscular Dystrophy Summer $2,000.00 Association--North Camp Program Haven, CT Muscular Dystrophy Montana Muscular Dystrophy $2,000.00 Association--Billings, Association Summer Camp 2017 MT Muscular Dystrophy MDA Limb Girdle Muscular $900,000.00 Association--Chicago, Dystrophy (LGMD) Genetic IL Testing Program Muscular Dystrophy 2017 Summer Camp $2,500.00 Association--Spokane, WA Muscular Dystrophy Muscle Walk $1,000.00 Association--Okemos, MI Muscular Dystrophy 2017 MDA Summer Camp of $2,500.00 Association--Tulsa, OK Oklahoma Muscular Dystrophy National Education and Impact $400,000.00 Association - Chicago, Partner IL Muscular Dystrophy MDA Summer Newsletter $2,000.00 Association--Columbia, SC Muscular Dystrophy 2017 MDA Summer Camp $2,500.00 Association--Cincinnat i, OH Muscular Dystrophy MDA Summer Camp $5,000.00 Association--Mountlake Terrace, WA Muscular Dystrophy MDA Summer Camp $5,000.00 Association--Denver, CO Muscular Dystrophy 2017 MDA Summer Camp $2,500.00 Association--Shrevepor t, LA Muscular Dystrophy 2017 MDA Summer Camp $8,000.00 Association--Dallas, TX Muscular Dystrophy MDA Summer Camp $2,500.00 Association--Bolingbro ok, IL Muscular Dystrophy Muscle Walk $1,000.00 Association--Denver, CO Muscular Dystrophy Muscle Walk $1,000.00 Association--Denver, CO Muscular Dystrophy Muscle Walk $1,000.00 Association--North Haven, CT Muscular Dystrophy Muscle Walk $1,000.00 Association--Maywood, NJ Muscular Dystrophy Muscle Walk $1,000.00 Association--Indianapo lis, IN Muscular Dystrophy Muscle Walk $1,000.00 Association--Urbana, IL Muscular Dystrophy Muscle Walk $1,000.00 Association--Louisvill e, KY Muscular Dystrophy Muscle Walk $1,000.00 Association--Chicago, IL Muscular Dystrophy Muscle Walk $1,000.00 Association--Edina, MN Muscular Dystrophy Muscle Walk $1,000.00 Association--Metairie, LA Muscular Dystrophy Muscle Walk $1,000.00 Association--Reston, VA Muscular Dystrophy Muscle Walk $1,000.00 Association--Little Rock, AR Muscular Dystrophy Muscle Walk $1,000.00 Association--Springfie ld, MO Muscular Dystrophy Muscle Walk $1,000.00 Association--Cedar Rapids, IA Muscular Dystrophy Muscle Walk $1,000.00 Association--Fort Myers, FL Muscular Dystrophy Muscle Walk $1,000.00 Association--Bolingbro ok, IL Muscular Dystrophy Muscle Walk $1,000.00 Association--Green Bay, WI Muscular Dystrophy Muscle Walk $1,000.00 Association--Edina, MN Muscular Dystrophy Muscle Walk $1,000.00 Association--Dallas, TX Muscular Dystrophy Quarterly Newsletter $3,000.00 Association--Westbrook , ME Muscular Dystrophy TORCH Award $5,000.00 Association--Midland, TX Muscular Dystrophy Muscle Walk $1,000.00 Association--St. Petersburg, FL Muscular Dystrophy 2017 MDA Muscle Walk of $1,000.00 Association--Jacksonvi Jacksonville lle, FL Muscular Dystrophy Muscle Walk $1,000.00 Association--Charlotte , NC Muscular Dystrophy Muscle Walk $1,000.00 Association--Towson, MD Muscular Dystrophy Muscle Walk $1,500.00 Association--Cedar Rapids, IA Muscular Dystrophy Muscle Walk & Fire Truck Pull $1,000.00 Association--Austin, TX Muscular Dystrophy Muscle Walk $1,500.00 Association--Sacrament o, CA Muscular Dystrophy Muscle Walk $1,000.00 Association--Cedar Rapids, IA Muscular Dystrophy Muscle Walk $1,000.00 Association--Fort Wayne, IN Muscular Dystrophy Muscle Walk $1,000.00 Association--Birmingha m, AL Muscular Dystrophy Muscle Walk $1,000.00 Association--Edina, MN Muscular Dystrophy Muscle Walk $1,000.00 Association--Salt Lake City, UT Muscular Dystrophy Muscle Walk $1,000.00 Association--Lafayette , LA Muscular Dystrophy Spring Newsletter $1,500.00 Association--Columbia, SC Muscular Dystrophy Muscle Walk $1,000.00 Association--Memphis, TN Muscular Dystrophy Muscle Walk $1,000.00 Association--Allentown , PA Muscular Dystrophy Muscle Walk $1,000.00 Association--Cedar Rapids, IA Muscular Dystrophy Muscle Walk $1,000.00 Association--Lafayette , LA Muscular Dystrophy Muscle Walk $1,000.00 Association--Maryland Heights, MO Muscular Dystrophy 1st Quarter Newsletter $1,000.00 Association--North Haven, CT Muscular Dystrophy Second Quarter Newsletter $1,500.00 Association--Chicago, IL Muscular Dystrophy Muscle Walk $1,000.00 Association--Cleveland , OH Muscular Dystrophy Muscle Walk $1,000.00 Association--Oklahoma City, OK Muscular Dystrophy Muscle Walk $1,000.00 Association--Wilmingto n, NC Muscular Dystrophy Muscle Walk $1,000.00 Association--San Antonio, TX Muscular Dystrophy Muscle Walk $1,000.00 Association--Scottsdal e, AZ Muscular Dystrophy Muscle Walk $1,000.00 Association--Montgomer y, AL Muscular Dystrophy First Quarter Newsletter $2,500.00 Association--Chicago, IL Muscular Dystrophy 4th Quarter Newsletter $1,500.00 Association--North Haven, CT Muscular Dystrophy Muscle Walk $1,000.00 Association--El Paso, TX Muscular Dystrophy Summer Camp 2017 $8,000.00 Association--Cypress, CA Muscular Dystrophy 1st Quarter Newsletter $3,000.00 Association--North Haven, CT Muscular Dystrophy Kids Art Auction $2,000.00 Association--Lake Mary, FL Muscular Dystrophy Muscle Walk $2,000.00 Association--Westborou gh, MA Muscular Dystrophy Muscle Walk $1,000.00 Association--Westborou gh, MA Muscular Dystrophy Muscle Walk $1,000.00 Association--Brentwood , TN Muscular Dystrophy Muscle Walk $1,000.00 Association--Lake Mary, FL Muscular Dystrophy Muscle Walk $1,000.00 Association--Brookfiel d, WI Muscular Dystrophy Muscle Walk $1,000.00 Association--Wichita, KS Muscular Dystrophy MA and RI Newsletters $10,000.00 Association--Westborou gh, MA Museum of Fine Arts Membership $20,000.00 Museum of Science Sanofi Genzyme Teacher $66,980.00 Sabbatical Program 2017-2018 Museum of Science Stars of STEM 2017 $10,000.00 National Bone Marrow Caregiver Webinar Series $2,500.00 Transplant Link National Comprehensive Membership $210,000.00 Cancer Network National Eczema Be Well, Mind + Body, Eczema $100,000.00 Association Awareness Month Campaign National Eczema NEA Educational Webcast for $15,000.00 Association Patients & Caregivers National Eczema Leaders in Eczema Forum $100,000.00 Association Series National Eczema Health Care Provider $85,000.00 Association Engagement Program National Eczema Patient Engagement Program $150,000.00 Association National Eczema Ambassadors Program $100,000.00 Association National Fabry Disease Fabry Family Conference $6,500.00 Foundation National Fabry Disease 2017 Urgent and Unmet Needs $40,000.00 Foundation Program National Fabry Disease 2017 Annual Educational $50,000.00 Foundation Conference and Fabry Family Camp National Fabry Disease Annual Conference $70,000.00 Foundation National Fabry Disease 2018 NFDF Core Program Grant $100,000.00 Foundation National Fabry Disease Fabry Family Meeting $3,000.00 Foundation National Fabry Disease Family Meeting $5,000.00 Foundation National Fabry Disease 2017 Family Assistance $10,000.00 Foundation Program National Gaucher CARE Programs $800,000.00 Foundation National Gaucher Optimal Health Initiative & $900,000.00 Foundation Education and Awareness National Gaucher CARE Programs $1,500,000.00 Foundation National Gaucher Optimal Health Initiative & $400,000.00 Foundation Education and Awareness National Kidney Kidney Walk $25,000.00 Foundation National Kidney Spring Clinical Meeting $3,500.00 Foundation National Kidney Kidney Health Risk Assessment $1,500.00 Foundation of Indiana Program National Kidney Kidney Health Risk Assessment $1,500.00 Foundation of Indiana Program National Kidney Kidney Health Risk Assessment $1,500.00 Foundation of Indiana Program National Kidney Kidney Health Risk Assessment $1,500.00 Foundation of Indiana Program National Kidney Kidney Walk $1,000.00 Foundation of Michigan National Kidney 31st Annual Gift of Life Gala $2,500.00 Foundation of Eastern Missouri, Metro East National MPS Society 2018 International MPS $100,000.00 Symposium National MPS Society National MPS Society Gala $134.00 Silent Auction National MPS Society National MPS Society Family $7,500.00 Conference Scholarships National MPS Society 31st Annual Family Conference $35,000.00 National MPS Society National MPS Society 2017 Run/ $20,000.00 Walk Program National Multiple Free From Falls $1,150.00 Sclerosis Society-- Southern California & Nevada Chapter National Multiple Champions on the Move $5,000.00 Sclerosis Society-- Upstate New York Chapter National Multiple Spellbound In the Vineyard $2,500.00 Sclerosis Society-- Upstate New York Chapter National Multiple 2016 Annual Meeting $2,500.00 Sclerosis Society-- Greater Delaware Valley Chapter National Multiple Women on the Move Luncheon $2,500.00 Sclerosis Society-- Greater Illinois Chapter National Multiple Life-Changing Breakthroughs: $65,000.00 Sclerosis Society-- MS Society Impact Series Colorado-Wyoming Chapter National Multiple Leadership Conference 2017 $15,000.00 Sclerosis Society-- Colorado-Wyoming Chapter National Multiple The Tykeson Fellows $15,000.00 Sclerosis Society-- Conference Colorado-Wyoming Chapter National Multiple Moving Mountains for MS: $10,000.00 Sclerosis Society-- Family Weekend Retreat Kentucky-Southeast Indiana Chapter National Multiple Crystal Boots and Silver $3,000.00 Sclerosis Society-- Spurs Kentucky-Southeast Indiana Chapter National Multiple Nationwide MS Navigator $50,000.00 Sclerosis Society-- Services Colorado-Wyoming Chapter National Multiple On the Move Luncheon $2,500.00 Sclerosis Society-- Gateway Area Chapter National Multiple Walk MS--Lanyard Sponsorship $10,000.00 Sclerosis Society--New Jersey Metro Chapter National Multiple On the Move Luncheon $2,500.00 Sclerosis Society-- South Central Chapter National Multiple Annual Meeting & Day of $7,500.00 Sclerosis Society--Mid Discovery Florida Chapter National Multiple Volunteer Program $10,000.00 Sclerosis Society--New Jersey Metro Chapter National Multiple Fall Crush Knoxville $2,500.00 Sclerosis Society--Mid South Chapter National Multiple Fall Crush Knoxville $2,500.00 Sclerosis Society--Mid South Chapter National Multiple Women Against MS Luncheon $3,000.00 Sclerosis Society--New York City Chapter National Multiple Challenge Walk MS $5,000.00 Sclerosis Society--New York City Chapter National Multiple On the Move Baltimore $3,500.00 Sclerosis Society--New York City Chapter National Multiple Ambassadors Ball $10,000.00 Sclerosis Society--New York City Chapter National Multiple Hispanic Outreach Initiative $10,000.00 Sclerosis Society--New York City Chapter National Multiple MS Scholarship Program $15,000.00 Sclerosis Society--New York City Chapter National Multiple 2017 Weekend Escape $5,000.00 Sclerosis Society--New York City Chapter National Multiple 2017 Dinner of Champions $2,500.00 Sclerosis Society-- Reno Chapter National Multiple Everyday Matters: Living Your $20,000.00 Sclerosis Society--New Best Life with MS York City Chapter National Multiple International Progressive MS $122,249.00 Sclerosis Society--New Alliance Industry Forum York City Chapter National Multiple 2017 On The Move Luncheon $2,500.00 Sclerosis Society--New York City Chapter National Multiple Books for a Better Life $20,000.00 Sclerosis Society--New Awards York City Chapter National Multiple Women on the Move Luncheon $6,000.00 Sclerosis Society--New York City Chapter National Multiple National ``Living with MS'' $600,000.00 Sclerosis Society--New Event York City Chapter National Multiple Walk MS 2017 $25,000.00 Sclerosis Society-- South Florida Chapter National Multiple Festival Hispano $1,500.00 Sclerosis Society-- South Florida Chapter National Multiple MS Gala Luncheon 2017 $2,500.00 Sclerosis Society-- South Florida Chapter National Multiple MS Walk West Virginia $7,500.00 Sclerosis Society-- Central Virginia Chapter National Multiple Patient Assistance Program $5,000.00 Sclerosis Society-- Indiana State Chapter National Multiple Walk MS $5,000.00 Sclerosis Society-- Long Island Chapter National Multiple Women on the Move Luncheon & $1,250.00 Sclerosis Society-- Fashion Show Ohio Valley Chapter National Multiple 2017 MS Neurology Dinner $5,000.00 Slcerosis Society-- Pacific South Coast Chapter National Multiple Challenge Walk MS $2,500.00 Slcerosis Society-- Pacific South Coast Chapter National Niemann-Pick Reinvention of The National $75,000.00 Disease Foundation Niemann Pick Disease Foundation (NNPDF) National Organization Rare Disease Day Fundraiser $10,000.00 for Rare Disorders National Organization 2017 Rare Diseases and Orphan $50,000.00 for Rare Disorders, Product Breakthrough Summit Inc. National Organization Running for Rare $5,000.00 for Rare Disorders, Inc. National Organization 2017 Corporate Council $25,000.00 for Rare Disorders, Inc. National Organization 2017 Rare Impact Awards $50,000.00 for Rare Disorders, Inc. National Organization Undiagnosed Diseases Network $5,000.00 for Rare Disorders, Fund Inc. National Organization Orphan Drug Act Advocacy $75,000.00 for Rare Disorders, Inc. National Parkinson Moving Day--Boston 2016 $1,000.00 Foundation National Society of 36th Annual Education $2,800.00 Genetic Counselors Conference National Tay-Sachs & Imagine & Believe $20,000.00 Allied Diseases Association, Inc. National Tay-Sachs & Raising Awareness of $1,100.00 Allied Diseases Ashkenazi Jewish Genetic Association, Inc. Diseases National Tay-Sachs & 39th Annual Family Conference $10,000.00 Allied Diseases Association, Inc. National Tay-Sachs & Family Support Resource Video $5,000.00 Allied Diseases Series and Podcasts Association, Inc. NEHI NEHI's Innovators in Health $25,000.00 Awards NEHI The Nick Littlefield Health $25,000.00 Policy Fellowship Neuroscience Centers of How to Improve Physical and $6,640.00 Florida Foundation, Psychological Health Program Inc. Neuroscience Centers of Maintaining Intimacy with $3,895.72 Florida Foundation, Multiple Sclerosis Inc. Next Step Fund, Inc. Summer Campference Program $10,000.00 Northeastern University Biotchnology College $1,000.00 Scholarship Northern California Congress Sponsorship $10,000.00 Rheumatology Society Northern New England Congress Sponsorship $2,000.00 Clinical Oncology Society Operation Warm, Inc. Boston Coat Program $20,000.00 Operation Warrior Wounded Military Event $798.00 Wishes Pan Massachusetts Pan Mass Challenge $11,000.00 Challenge Patient Access Network Patient Assistance Program $460,000.00 Foundation Patient Access Network Patient Assistance Program $200,000.00 Foundation Patient Services, Inc. Patient Assistance Program $481,250.00 Patient Services, Inc. Patient Assistance Program $2,902,500.00 Patient Services, Inc. Patient Assistance Program $237,500.00 Patient Services, Inc. Patient Assistance Program $818,750.00 Patient Services, Inc. Patient Assistance Program $650,000.00 Patient Services, Inc. Patient Assistance Program $5,960,000.00 PCMA Pharmaceutical Congress Sponsorship $60,000.00 Care Management Association Pediatric Endocinology Congress Sponsorship $6,200.00 Nursey Society Pediatric Endocrine Congress Sponsorship $27,500.00 Society Peer Health Exchange, Peer Health Exchange Program $5,000.00 Inc. Pennsylvania Congress Sponsorship $10,000.00 Rheumatology Society Perkins School for the Enhancing Accessible Science $20,000.00 Blind and Technology Education eLearning Program Philadelphia Rheumatism 5th Annual Ralph Schumacher $2,250.00 Society Lecture Phillips Brooks House Bridges Workshop $3,000.00 Association Incorporated President and Fellows The Family Van Health Clinic $50,000.00 of Harvard College Pro Player Foundation Flavors of Austin Fundraiser $5,000.00 Project HOPE Project Hope Gala $10,000.00 Project Just Because, 211 Domestic Abuse/Emergency $10,000.00 Inc. Program & Keep A Family Warm Program Prostate Cancer Academy Proscate Cancer Academy 2017 $7,500.00 Race to Erase MS 24th Annual Race to Erase MS $15,000.00 Race to Erase MS Race to Erase MS $10,000.00 Radiological Society of 103rd Scientific Assembly and $3,500.00 North America Annual Meeting Rare Disease United 14th Annual World Symposium-- $20,000.00 Foundation Lysosomal Diseases Rare Genomics Institute Patient Advoacy Leadership $25,000.00 Awards and Rare Disease Patient Advocate Teaching Modules Rare New England, Inc. Improving Health Care $3,000.00 Experiences in the Rare Disease Community Read to a Child, Inc. Read to a Child's Lunchtime $5,000.00 Reading Program Resolve Community Volunteer Match $1,000.00 Counseling Center, Inc. Rheumatology Congress Sponsorship $2,000.00 Association of IOWA Rheumatology Congress Sponsorship $20,000.00 Association of Minnesota and the Dakotas Rheumatology Congress Sponsorship $10,000.00 Association of Nevada Rheumatology Nurses Immunology Webinar $50,000.00 Society Rheumatology Nurses 10th Rheumatology Nurses $3,443.91 Society Society Annual Conference Rise Against Hunger Volunteer Match $2,944.08 Rise Against Hunger Volunteer Match $2,944.08 Rocky Mountain Multiple MS4MS Fundraising Program $5,000.00 Sclerosis Center Rocky Mountain Multiple 2017 Webinar Program Series $5,000.00 Sclerosis Center Rocky Mountain Multiple 2016 Fall Education Summit $5,000.00 Sclerosis Center Samaritans, Inc. Youth Suicide Prevention $25,000.00 Services Saunders Health 2017 Night of Lights $2,500.00 Services Foundation Saunders Health 2016 Night of Lights $1,000.00 Services Foundation Save One Life, Inc. Panel Discussion Donation $250.00 Scholarship America, TORCH Awards Program $11,600.00 Inc. Scholarship America, Scholarship Program $39,900.00 Inc. Science Club For Girls, 10th Annual Catalyst Awards $10,000.00 Inc. Science Club For Girls, STEMinistas Program Expansion $10,000.00 Inc. Society of Nuclear Congress Sponsorship $1,250.00 Medicine and Molecular Imaging Society of Nuclear Congress Sponsorship $2,200.00 Medicine and Molecular Imaging Society of Nuclear Congress Sponsorship $7,790.00 Medicine and Molecular Imaging Society of Nuclear Congress Sponsorship $1,800.00 Medicine and Molecular Imaging Special Olympics Bio-Ball 2017 $2,500.00 Massachusetts Inc. Sportsmen's Tennis & Academic Enrichment Program $12,500.00 Enrichment Center St. Francis House Triage and Coordinated Care $10,000.00 for the Poor and Homeless Population St. Mary's Center for Women@Work Plus Program $15,000.00 Women and Children State of Texas Congress Sponsorships $20,000.00 Association of Rheumatologists Temple Beth Sholom [The Jewish Genetic Disease $7,000.00 Tribe] Awareness Screening The American Congress Sponsorship $20,000.00 Association of Clinical Endocrinologists (AACE) The American Society of Congress Sponsorship $10,000.00 Hematology The Boston Home, Inc. The Boston Home Arts Program $5,000.00 The Boston Home, Inc. Socialization & Wellness $9,000.00 Program The Boston Home, Inc. Resident & Family 2017 Event $10,000.00 Series The Boston Home, Inc. 135 Anniversary Event $10,000.00 The Community Art Teen Media Program $15,000.00 Center The Community Art General Operating Support $10,000.00 Center The Forsyth Institute Mobile Dental Program Service $10,000.00 The Greater Boston Food Volunteer Match $1,000.00 Bank, Inc. The Leukemia & Lymphoma Light The Night Event $10,000.00 Society Eastern PA Chapter The Leukemia & Lymphoma Light The Night Event $20,000.00 Society, Inc. The MAGIC Foundation 23rd Annual Convention $5,000.00 The McCourt Foundation Tour de South Shore--Bike/ $7,500.00 Walk The McCourt Foundation MS Educational Program Update $20,000.00 The Menkes Foundation The Rare Disease Film $3,000.00 Festival The MS Center of St 12th Annual Trivia and $15,000.00 Louis Auction Benefit The Oak Clinic Wellness Thursday Nutrition $21,000.00 for MS Seminars The Oak Clinic 2017 Oak Clinic Acorn Run $3,500.00 The Oak Clinic 2017 Diamond Run for MS $5,000.00 The Oak Clinic Wellness Wednesday Nutrition $14,000.00 for MS Seminars The Posse Foundation STEM Posse Program $25,000.00 The Possible Project Powering Possibilities Gala $10,000.00 The Regents of the Rare Disease Symposium $10,000.00 University of California, San Francisco The University of Texas Congress Sponsorship $10,000.00 MD Anderson Cancer Center Thompson Island Outward Connections--Science $15,000.00 Bound Education Education for Boston Public Center, Inc. School Students Thompson Island Outward Thompson Island 4K Trail Run $5,000.00 Bound Education Center, Inc. ThyCa: Thyroid Cancer Production and Distribution $15,000.00 Survivors' of Educational Handbooks and Association, Inc. Materials ThyCa: Thyroid Cancer 20th International Thyroid $35,000.00 Survivors' Cancer Survivors' Conference Association, Inc. Tisch Multiple 2017 Future Without MS Gala $10,000.00 Sclerosis Research Center of New York, Inc. Tisch Multiple Healing MS: Online Newsletter $8,000.00 Sclerosis Research Center of New York, Inc. Tri-State Multiple Owensboro Autumn Walk $2,500.00 Sclerosis Association Tri-State Multiple Evansville Autumn Walk $2,500.00 Sclerosis Association Tutoring Plus of STEAM Enrichment Programs $7,500.00 Cambridge, Inc. UMASS Dartmouth Allston Brighton College $2,000.00 Scholarship United Arizona Congress Sponsorship $45,000.00 Rheumatology Alliance United Network For Congress Sponsorship $8,400.00 Organ Sharing United Pompe Foundation Reception and Early Onset $30,000.00 Pompe Patient Meeting United Pompe Foundation Reception and Early Onset $45,000.00 Pompe Patient Meeting United Pompe Foundation General Operating Support $50,000.00 United Rheumatology Congress Sponsorship $130,000.00 United Rheumatology Congress Sponsorship $140,000.00 United States Bone and General Program Support $46,250.00 Joint Initiative, NFP United States Bone and The Burden of Musculoskeletal $25,000.00 Joint Initiative, NFP Diseases in the United States United States Bone and Membership $20,000.00 Joint Initiative, NFP United States Bone and Patient Education Programs $80,000.00 Joint Initiative, NFP University Hospitals 40th Anniversary Bone Marrow $5,000.00 Health System, Inc. Transplant Celebration University Neurology, 2017 NYSMSC Annual Meeting $5,000.00 Inc. University of Sanofi Genzyme Biotchnology $3,000.00 Connecticut Foundation College Scholarship University of Student Success Program $200,000.00 Massachusetts Foundation, Inc. University of Sanofi Genzyme Biotchnology $4,000.00 Massachusetts: Lowell College Scholarship University of Miami Sanofi Genzyme Biotchnology $1,000.00 College Scholarship University of Congress Sponsorship $23,500.00 Minnesota--Department of Surgery University of New Sanofi Genzyme Biotchnology $4,000.00 Hampshire College Scholarship University of Congress Sponsorship $2,500.00 Pennsylvania Us TOO International 13th Annual SEA Blue Prostate $5,000.00 Cancer Walk & Run VCU Hume-Lee Transplant Congress Sponsorship $1,000.00 Center Visiting Nurse Heroes in Health Care Gala $10,000.00 Association of Boston & Affiliates VZW Sint-Aloysius Oud Volunteer Match $2,000.00 Scouts Geel Washington University Washington University Fellows $1,500.00 in St. Louis; Siteman Program Cancer Center Wentworth Institute of Sanofi Genzyme Biotchnology $500.00 Technology College Scholarship West End House Boys and Volunteer Match $1,000.00 Girls Club WGBH Educational WGBH Pledge Night Event $12,000.00 Foundation Whitehead Institute for Expedition: Bio 2018 Program $10,000.00 Biomedical Research Wisconsin Rheumatology Congress Sponsorship $10,000.00 Association Women's Lunch Place 2017 Spaghetti Dinner $10,000.00 Women's Lunch Place Healthy Meals Program $35,000.00 WORLD Symposium Congress Sponsorship $40,000.00 WORLD Symposium Congress Sponsorship $600.00 WORLD Symposium Congress Sponsorship $1,200.00 WORLD Symposium Congress Sponsorship $25,000.00 WORLD Symposium Congress Sponsorship $63,000.00 WORLD Symposium Congress Sponsorship $210,000.00 WORLD Symposium Congress Sponsorship $160,000.00 WORLD Symposium Congress Sponsorship $5,000.00 WriteBoston Chelsea and WriteBoston $18,000.00 Educational Programs Wylder Nation 4th Annual Living Like a $15,000.00 Foundation Warrior Gala YMCA of Greater Boston Summer Day Camp Scholarships $15,000.00 for Low-Income Youth Young Men's Christian MS One Step Program $15,000.00 Association of Montclair, NJ ziMS Foundation 8th Annual UVA MS Event $5,000.00 ziMS Foundation 7th Annual UVA MS Event $5,000.00 Sponsorships, Charitable Donations, Memberships and Fellowships 1st Jan 2018-31st Dec 2018 Sanofi US and its affiliate Genzyme Corporation are committed to supporting sponsorships for specific activities and initiatives of healthcare organizations and institutions, independent medical or professional societies, trade organizations and organized patient groups to improve patient care and provide information to the medical and/or patient communities. The goal of our charitable giving approach is to fund general operational support for patient/disease organizations, or program support for community-based organizations. Sanofi US and Genzyme Corporation are part of the Sanofi Group, a global pharmaceutical company. Applicant names are provided by the requestor. If applicants apply as a group for a single activity; all applicants may be not be identified above. ``Funding Amount'' is the amount that the Company funded during 2018 identified above. ``Funding Amount'' does not include funds that may have been provided by other affiliated Sanofi Company Entities (e.g., Sanofi Pasteur). ------------------------------------------------------------------------ Recipient Name(s) Activity Title Funding Amount ------------------------------------------------------------------------ 495 MetroWest Membership $10,000.00 Partnership ------------------------------------------------------------------------ ACMG Congress Sponsorship $33,000.00 ------------------------------------------------------------------------ ACMG Congress Sponsorship $7,600.00 ------------------------------------------------------------------------ ACMG Congress Sponsorship $500.00 ------------------------------------------------------------------------ ACMG Congress Sponsorship $4,500.00 ------------------------------------------------------------------------ ACTRIMS Congress Sponsorship $42,500.00 ------------------------------------------------------------------------ Alabama Cancer Congress Membership $4,000.00 ------------------------------------------------------------------------ Alliance for Membership $100,000.00 Regenerative Medicine ------------------------------------------------------------------------ Allston Village Main Community Event $1,000.00 Streets Inc. ------------------------------------------------------------------------ American Academy of DataDerm Program $350,000.00 Dermatology ------------------------------------------------------------------------ American Academy of Quality Innovation Center $50,000.00 Dermatology (QIC) Program ------------------------------------------------------------------------ American Academy of AccessDerm Program $250,000.00 Dermatology ------------------------------------------------------------------------ American Academy of 2019 President's Fundraiser $275,000.00 Dermatology ------------------------------------------------------------------------ American Academy of Practice Management Center $100,000.00 Dermatology Program ------------------------------------------------------------------------ American Academy of 2018 President's Fundraiser $275,000.00 Dermatology ------------------------------------------------------------------------ American Academy of Congress Sponsorship $1,000.00 Neurology Institute ------------------------------------------------------------------------ American Academy of Congress Sponsorship $500.00 Neurology Institute ------------------------------------------------------------------------ American Academy of Congress Sponsorship $500.00 Neurology Institute ------------------------------------------------------------------------ American Academy of Congress Sponsorship $15,000.00 Neurology Institute ------------------------------------------------------------------------ American Academy of Congress Sponsorship $81,000.00 Neurology Institute ------------------------------------------------------------------------ American Academy of Congress Sponsorship $598,935.00 Neurology Institute ------------------------------------------------------------------------ American Academy of Women Leading in Neurology $20,000.00 Neurology Institute Program ------------------------------------------------------------------------ American Academy of Transforming Leaders Program $25,000.00 Neurology Institute ------------------------------------------------------------------------ American Academy of Palatucci Advocacy Leadership $30,000.00 Neurology Institute Forum ------------------------------------------------------------------------ American Academy of 2018 Industry Roundtable $50,000.00 Neurology Institute ------------------------------------------------------------------------ American Academy of Diversity Leadership Program $30,000.00 Neurology Institute ------------------------------------------------------------------------ American Association Congress Sponsorship $26,500.00 for Pediatric Ophthalmology & Strabismus ------------------------------------------------------------------------ American Association of Congress Sponsorship $100.00 Clinical Endocrinologists ------------------------------------------------------------------------ American Association of Congress Sponsorship $50,000.00 Neuromuscular & Electrodiagnostic Medicine ------------------------------------------------------------------------ American Association of Congress Sponsorship $2,100.00 Neuromuscular & Electrodiagnostic Medicine ------------------------------------------------------------------------ American Association of Congress Sponsorship $990.00 Neuromuscular & Electrodiagnostic Medicine ------------------------------------------------------------------------ American City Business Corporate Citizenship Awards $5,500.00 Journals, Inc. 2018 ------------------------------------------------------------------------ American College of Industry Advisory Council $60,000.00 Chest Physicians 2018 ------------------------------------------------------------------------ American College of Congress Sponsorship $7,600.00 Medical Genetics and Genomics ------------------------------------------------------------------------ American College of Congress Sponsorship $17,500.00 Medical Genetics and Genomics ------------------------------------------------------------------------ American College of Congress Sponsorship $10,000.00 Medical Genetics and Genomics ------------------------------------------------------------------------ American College of Fellowship Program $75,000.00 Medical Genetics Foundation ------------------------------------------------------------------------ American College of Fellowship Program $75,000.00 Medical Genetics Foundation ------------------------------------------------------------------------ American College of Congress Sponsorship $10,000.00 Rheumatology ------------------------------------------------------------------------ American College of Congress Sponsorship $15,000.00 Rheumatology ------------------------------------------------------------------------ American Society for Conference Sponsorship $10,000.00 Blood and Marrow Transplant ------------------------------------------------------------------------ American Society for Sarah Cannon Blood Cancer $10,000.00 Blood and Marrow Network Event Transplant ------------------------------------------------------------------------ American Society for ASBMT Website Sponsorship $15,000.00 Blood and Marrow Transplant ------------------------------------------------------------------------ American Society of Congress Sponsorship $118,000.00 Clinical Oncology ------------------------------------------------------------------------ American Society of Congress Sponsorship $358,750.00 Clinical Oncology ------------------------------------------------------------------------ American Society of Congress Sponsorship $285,500.00 Hematology ------------------------------------------------------------------------ American Society of Congress Sponsorship $75,000.00 Hematology ------------------------------------------------------------------------ American Society of Congress Sponsorship $3,000.00 Human Genetics ------------------------------------------------------------------------ American Society of Congress Sponsorship $5,000.00 Nephrology ------------------------------------------------------------------------ American Society of Congress Sponsorship $3,600.00 Nephrology ------------------------------------------------------------------------ American Society of Congress Sponsorship $25,000.00 Transplant Surgeons ------------------------------------------------------------------------ American Society of Congress Sponsorship $36,750.00 Transplant Surgeons ------------------------------------------------------------------------ American Thoracic ATS 2018 Corporate Member $50,000.00 Society Program ------------------------------------------------------------------------ American Thyroid Congress Sponsorship $5,000.00 Association ------------------------------------------------------------------------ American Transplant Congress Sponsorship $153,000.00 Congress ------------------------------------------------------------------------ Americas Committee for Congress Sponsorship $42,500.00 Treatment and Research in Multiple Sclerosis, Inc. ------------------------------------------------------------------------ Americas Committee for Congress Sponsorship $12,480.00 Treatment and Research in Multiple Sclerosis, Inc. ------------------------------------------------------------------------ Americas Committee for Congress Sponsorship $19,000.00 Treatment and Research in Multiple Sclerosis, Inc. ------------------------------------------------------------------------ America's Physician Congress Sponsorship $4,500.00 Groups ------------------------------------------------------------------------ ANERA (American Near Anera 50th Anniversary $10,000.00 East Refugee Aid) Fundraiser ------------------------------------------------------------------------ Ann & Robert H. Lurie MPS Patient and Family Day $2,500.00 Children's Hospital of Chicago ------------------------------------------------------------------------ Ann & Robert H. Lurie Fellowship Program $75,000.00 Children's Hospital of Chicago ------------------------------------------------------------------------ Ann & Robert H. Lurie Fellowship Program $75,000.00 Children's Hospital of Chicago ------------------------------------------------------------------------ Arthritis Foundation Congress Sponsorship $7,500.00 Northern California Office ------------------------------------------------------------------------ Arts & Business Council Battle of the Biotech Bands $5,250.00 of Greater Boston, Inc. ------------------------------------------------------------------------ ASCO Exhibits Congress Sponsorship $5,495.00 Management ------------------------------------------------------------------------ ASCO Exhibits Congress Sponsorship $18,990.00 Management ------------------------------------------------------------------------ Asembia Specialty Congress Sponsorship $20,000.00 Pharmacy Summit LLC ------------------------------------------------------------------------ Asembia Specialty Congress Sponsorship $20,000.00 Pharmacy Summit LLC ------------------------------------------------------------------------ Asembia Specialty Congress Sponsorship $20,000.00 Pharmacy Summit LLC ------------------------------------------------------------------------ ASN Congress Sponsorship $7,200.00 ------------------------------------------------------------------------ ASN Congress Sponsorship $72,500.00 ------------------------------------------------------------------------ ASPHO Congress Sponsorship $3,000.00 ------------------------------------------------------------------------ Association of Managed Congress Sponsorship $20,000.00 Care Pharmacy (AMCP) ------------------------------------------------------------------------ Association of Northern Membership $1,200.00 California Oncologists ------------------------------------------------------------------------ Association of VA Congress Sponsorship $10,000.00 Hematology/Oncology ------------------------------------------------------------------------ Association of Women in AWIR 2018 Corporate Program $75,000.00 Rheumatology ------------------------------------------------------------------------ Bendcare Congress Sponsorship $180,000.00 ------------------------------------------------------------------------ Bendcare Congress Sponsorship $165,000.00 ------------------------------------------------------------------------ Big Brothers Big Mentoring Youth in Science $15,000.00 Sisters of Central Technology Engineering and Mass Metrowest Inc. Math (MySTEM) ------------------------------------------------------------------------ Biomedical Science Evening of Hope 2018 $75,000.00 Careers Program ------------------------------------------------------------------------ Biomedical Science Hope Scholarship 2018-2019 $7,500.00 Careers Program ------------------------------------------------------------------------ Bleeding Disorders Patient Education Program $7,000.00 Alliance Illinois ------------------------------------------------------------------------ Blue Cross Blue Shield Congress Sponsorship $17,500.00 Association ------------------------------------------------------------------------ Boston Area Rape Crisis Medical Advocacy Program $30,000.00 Center ------------------------------------------------------------------------ Boston Area Rape Crisis Medical Advocacy (MedAd) $30,000.00 Center Program ------------------------------------------------------------------------ Boston Children's Fellowship Program $75,000.00 Hospital Corporation ------------------------------------------------------------------------ Boston College Membership $10,000.00 ------------------------------------------------------------------------ Boston Educational Boston Public Schools Science $10,000.00 Development Fair Foundation, Inc. ------------------------------------------------------------------------ Boston Health Care For Life Essentials Fund $35,000.00 The Homeless Program Inc. ------------------------------------------------------------------------ Boston Partners in Power Lunch, 2017-2018 $6,000.00 Education, Inc. ------------------------------------------------------------------------ Boston Plan for Boston Teacher Residency: $15,000.00 Excellence in The Building a Diverse Pipeline Public Schools of STEM Educators for BPS Foundation ------------------------------------------------------------------------ Boston Private Industry 2018 Corporate Contributions $15,000.00 Council Campaign ------------------------------------------------------------------------ Boston University Congress Sponsorship $1,500.00 Continuing Medical Education ------------------------------------------------------------------------ Bottom Line Boston STEM Success Program $15,000.00 ------------------------------------------------------------------------ Boys and Girls Clubs of 2018 Bids for Kids Auction & $10,000.00 MetroWest fundraising event ------------------------------------------------------------------------ Boys and Girls Clubs of Operating Support $25,000.00 MetroWest ------------------------------------------------------------------------ Breakthrough Greater Full STEAM Ahead Support $15,000.00 Boston ------------------------------------------------------------------------ California Dermatology Congress Sponsorship $15,000.00 Physician Assistant Society ------------------------------------------------------------------------ California Rheumatology Congress Sponsorship $50,000.00 Alliance ------------------------------------------------------------------------ Cambridge Chamber of Membership $7,250.00 Commerce ------------------------------------------------------------------------ Cambridge Chamber of 2018 Visionary Awards $3,250.00 Commerce ------------------------------------------------------------------------ Cambridge Chamber of Community support program $7,500.00 Commerce ------------------------------------------------------------------------ Cambridge School Fundraiser for Cambridge $10,000.00 Volunteers, Inc. Schools ------------------------------------------------------------------------ Cambridge School Fundraiser for Cambridge $10,000.00 Volunteers, Inc. Schools ------------------------------------------------------------------------ Cambridge School Reading Buddies--Fletcher $16,818.00 Volunteers, Inc. Maynard Academy Support ------------------------------------------------------------------------ Cambridge School Reading Buddies--Fletcher $16,423.00 Volunteers, Inc. Maynard Academy Support ------------------------------------------------------------------------ Cancer Research CRI's Webinar Series: Cancer $25,000.00 Institute Immunotherapy and You ------------------------------------------------------------------------ Case Management Society CMSA's 28th Annual Conference $1,725.00 of America & Expo ------------------------------------------------------------------------ Case Management Society CMSA's 28th Annual Conference $14,000.00 of America & Expo ------------------------------------------------------------------------ Case Management Society CMSA's 28th Annual Conference $5,500.00 of America & Expo ------------------------------------------------------------------------ Case Management Society Corporate Sponsorship of $1,250.00 of New England CMSNE ------------------------------------------------------------------------ Case Management Society Patient Education and $1,550.00 of New England Awareness Program ------------------------------------------------------------------------ Case Management Society Patient Education and $1,000.00 of New England Awareness Program ------------------------------------------------------------------------ Center for Congress Sponsorship $133,900.00 International Blood and Marrow Transplant Research ------------------------------------------------------------------------ CEO Roundtable on Membership $40,000.00 Cancer ------------------------------------------------------------------------ Charles River Community Mom and Baby Program $15,000.00 Health ------------------------------------------------------------------------ CheckOrphan Rare Disease Page Sponsorship $11,000.00 ------------------------------------------------------------------------ Child Neurology Society Congress Sponsorship $4,250.00 ------------------------------------------------------------------------ Children Health and Fellowship Program $75,000.00 Research Foundation, Inc. ------------------------------------------------------------------------ Childrens Gaucher Research: A novel iPSC-based $75,000.00 Research Fund system to elucidate the molecular mechanisms leading to neuronopathic Gaucher disease ------------------------------------------------------------------------ Children's Hospital Fellowship Program $75,000.00 Corporation ------------------------------------------------------------------------ Children's Hospital of 2019-2020 UCLA Intercampus $75,000.00 Orange County Medical Biochemical Genetics Training Program ------------------------------------------------------------------------ Children's Hospital of Fellowship Program $75,000.00 Philadelphia ------------------------------------------------------------------------ Citizen Schools STEM Learning at Somerville's $15,000.00 East Somerville Community School ------------------------------------------------------------------------ Citizen Schools STEM Learning for High-Need $15,000.00 Middle School Students in Somerville ------------------------------------------------------------------------ CitySprouts, Inc. Middle School Program $8,000.00 ------------------------------------------------------------------------ CitySprouts, Inc. Middle School Program $8,000.00 ------------------------------------------------------------------------ Cleveland Clinic Congress Sponsorship $3,500.00 Educational Foundation ------------------------------------------------------------------------ Coalition of Hematology Membership $6,000.00 Oncology Practices ------------------------------------------------------------------------ Collegium 32nd Symposium of the $25,000.00 Internationale Collegium Internationale Allergologicum Allergologicum ------------------------------------------------------------------------ Community Boating, Inc. Operating Support $15,000.00 ------------------------------------------------------------------------ Community Farms Community Food Access $15,000.00 Outreach Programs ------------------------------------------------------------------------ Community Servings, Pie in the Sky $10,000.00 Inc. ------------------------------------------------------------------------ Community Servings, General Operating Support $30,000.00 Inc. ------------------------------------------------------------------------ Community Servings, Volunteer Match $1,000.00 Inc. ------------------------------------------------------------------------ Community Servings, Nutrition Program for $30,000.00 Inc. Individuals & Families Affected by Multiple Sclerosis and Other Acute Life-Threatening Illnesses ------------------------------------------------------------------------ Consortium of Multiple Congress Sponsorship $8,000.00 Sclerosis Centers ------------------------------------------------------------------------ Consortium of Multiple Congress Sponsorship $21,000.00 Sclerosis Centers ------------------------------------------------------------------------ Consortium of Multiple Congress Sponsorship $22,200.00 Sclerosis Centers ------------------------------------------------------------------------ Consortium of Multiple Congress Sponsorship $1,200.00 Sclerosis Centers ------------------------------------------------------------------------ Consortium of Multiple Congress Sponsorship $6,000.00 Sclerosis Centers ------------------------------------------------------------------------ Consortium of Multiple Congress Sponsorship $1,500.00 Sclerosis Centers ------------------------------------------------------------------------ Consortium of Multiple North American Registry for $200,000.00 Sclerosis Centers Care and Research in Multiple Sclerosis (NARCRMS) 2018 Support ------------------------------------------------------------------------ Cradles To Crayons Inc. Ready for School Program $20,000.00 ------------------------------------------------------------------------ Critical Path Institute Transplant Therapeutics $55,000.00 Consortium ------------------------------------------------------------------------ DEAF, Inc.-- Deaf-Accessible Medical Case $10,000.00 Developmental Management Program Evaluation and Adjustment Facilities, Inc. ------------------------------------------------------------------------ Deep South Cancer 2018 Magic City Cycliad $5,000.00 Foundation ------------------------------------------------------------------------ Dermatology Nurses DNA 2018 Corporate Membership $3,000.00 Association ------------------------------------------------------------------------ Dimock Community 4th Annual Road to Wellness $1,000.00 Foundation Inc. 5K Walk/Run ------------------------------------------------------------------------ Dimock Community 31st Annual Fundraiser $100,000.00 Foundation Inc. ------------------------------------------------------------------------ Duke University Fellowship Program $75,000.00 ------------------------------------------------------------------------ East End House Inc. Generating and Evaluating New $20,000.00 Adventures in Science After School (GENASAS) ------------------------------------------------------------------------ East End House Inc. Generating and Evaluating New $20,000.00 Adventures in Science After School (GENASAS) ------------------------------------------------------------------------ Emory University Fellowship Program $75,000.00 ------------------------------------------------------------------------ Emory University JScreen Jewish Genetic $100,000.00 Disease Education Initiative ------------------------------------------------------------------------ Family Promise Capital Campaign: A Place to $25,000.00 Metrowest Inc. Call Home ------------------------------------------------------------------------ Florida Society of Membership $25,000.00 Clinical Oncology ------------------------------------------------------------------------ Florida Society of Living with Prostate Cancer $3,750.00 Clinical Oncology ------------------------------------------------------------------------ Florida Society of Congress Sponsorship $35,600.00 Rheumatology ------------------------------------------------------------------------ Food For Free Home Delivery--A Nutrition $15,000.00 Committee, Inc. Program for Seniors and People with Disabilities ------------------------------------------------------------------------ Foundation of the Multiple Sclerosis Workforce $31,225.00 Consortium of MS of the Future: Medical Centers Student Research Scholarships ------------------------------------------------------------------------ Foundation of the 2018 FCMSC Neurology Resident $10,000.00 Consortium of MS Annual Meeting Scientific Centers Scholarships ------------------------------------------------------------------------ Foundation of the NARCOMS NOW 2018 $15,000.00 Consortium of MS Centers ------------------------------------------------------------------------ Foundation of the Foundation of the Consortium $10,000.00 Consortium of MS of Multiple Sclerosis Centers Centers 2018 Mission Support ------------------------------------------------------------------------ Framingham Townwide Pto Barbieri school holiday gift $1,000.00 Council drive ------------------------------------------------------------------------ Franciscan Hospital For Adaptive Sports Program $15,000.00 Children Inc. ------------------------------------------------------------------------ Friends of Resiliency Dropout Prevention Academic $10,000.00 for Life Inc. Services ------------------------------------------------------------------------ Generation Citizen Inc. Generation Citizen $10,000.00 Massachusetts Civics Day ------------------------------------------------------------------------ Generation Citizen Inc. Volunteer Match $1,000.00 ------------------------------------------------------------------------ Georgia Dermatology of Congress Sponsorship $35,000.00 Physician Assistants (GDPA) ------------------------------------------------------------------------ Georgia Society of Membership $6,000.00 Clinical Oncology ------------------------------------------------------------------------ Georgia Society of Congress Sponsorship $10,000.00 Dermatology and Dermatologic Surgery ------------------------------------------------------------------------ Georgia Society of Congress Sponsorship $10,000.00 Rheumatology ------------------------------------------------------------------------ Georgia Society of Congress Sponsorship $2,100.00 Rheumatology ------------------------------------------------------------------------ Girl Scouts of Eastern Girls Building Self-eSTeEM $15,000.00 Massachusetts Inc. ------------------------------------------------------------------------ Global Academy for Congress Sponsorship $65,000.00 Medical Education, Inc. ------------------------------------------------------------------------ Global Academy for Congress Sponsorship $40,037.50 Medical Education, Inc. ------------------------------------------------------------------------ Global Alliance for Membership $50,000.00 Patient Access ------------------------------------------------------------------------ Global Genes In-kind donation $11,128.38 ------------------------------------------------------------------------ Global Genes Access Program $25,000.00 ------------------------------------------------------------------------ Global Genes 2018 Patient Advocacy Summit: $2,500.00 Advocacy Support ------------------------------------------------------------------------ Global Genes 2018 RARE Corporate Alliance $25,000.00 ------------------------------------------------------------------------ Global Genes 2018 Patient Advocacy Summit $50,000.00 ------------------------------------------------------------------------ Global Genes RARE Global Advocacy $10,000.00 Leadership Symposium ------------------------------------------------------------------------ Global Genes 2018 RARE Education Programs $25,000.00 ------------------------------------------------------------------------ Global Genes 2018 Rare Disease Hub $5,000.00 ------------------------------------------------------------------------ Global Genes 2019 Corporate Alliance $25,000.00 ------------------------------------------------------------------------ Gordon Research Lysosomal storage diseases $10,000.00 Conferences Program ------------------------------------------------------------------------ Greater Boston Chamber Membership $4,000.00 of Commerce ------------------------------------------------------------------------ Greenwood Genetic Fellowship Program $74,764.00 Center Inc. ------------------------------------------------------------------------ Greenwood Genetic Fellowship Program $74,991.00 Center Inc. ------------------------------------------------------------------------ Habitat For Humanity Fundraiser Event $10,000.00 Metrowest--Greater Worcester Inc. ------------------------------------------------------------------------ Habitat For Humanity Affordable Home Build Program $20,000.00 Metrowest--Greater Worcester Inc. ------------------------------------------------------------------------ Habitat For Humanity of Corporate Build Day $1,500.00 North Central Massachusetts ------------------------------------------------------------------------ Harvard Medical School Congress Sponsorship $2,500.00 Global and Continuing Education ------------------------------------------------------------------------ Health Care For All Framingham Area Health Care $15,000.00 Inc. Access Education and Outreach Campaign ------------------------------------------------------------------------ Health Resources in The Leaders through $25,000.00 Action Inc. Education, Action and Hope (LEAH) Project ------------------------------------------------------------------------ Health Resources in The Leaders through $866.75 Action Inc. Education, Action and Hope (LEAH) Project ------------------------------------------------------------------------ Hearts & Noses Hospital Ongoing Bedside Hospital $15,000.00 Clown Troupe Inc. Clown Visits to Ill and Disabled Children in Greater Boston ------------------------------------------------------------------------ Hemostasis and Membership $10,000.00 Thrombosis Research Society ------------------------------------------------------------------------ Hope and Comfort Inc. Hope and Comfort: Personal $10,000.00 Hygiene Products to Low- Income Individuals and Families ------------------------------------------------------------------------ Horizons for Homeless STEAM Education for Young $10,000.00 Children Homeless Children ------------------------------------------------------------------------ Illinois Society of Congress Sponsorship $25,000.00 Dermatology Physicians Assistants ------------------------------------------------------------------------ Imedex, LLC Congress Sponsorship $99,900.00 ------------------------------------------------------------------------ Institute for Cancer 2018 In Vino Vita Fundraising $10,000.00 Research dba The Event Research Institute of Fox Chase Cancer Center ------------------------------------------------------------------------ International Eczema Congress Sponsorship $200,000.00 Council ------------------------------------------------------------------------ International Institute 2018 Golden Door Award $10,000.00 of New England Fundraiser ------------------------------------------------------------------------ International Institute Healthcare Navigation for $15,000.00 of New England Refugees in Boston ------------------------------------------------------------------------ International Myeloma Congress Sponsorship $450,000.00 Workshop, c/o SPARGO, Inc. ------------------------------------------------------------------------ International 2018 MS Perspectives Program $40,000.00 Organization of Multiple Sclerosis Nurses ------------------------------------------------------------------------ International 2018 IOMSN Mission Support $10,000.00 Organization of Multiple Sclerosis Nurses ------------------------------------------------------------------------ International Society Congress Sponsorship $11,799.99 on Thrombosis and Haemostasis ------------------------------------------------------------------------ Italian Home For Volunteer Match $1,000.00 Children Inc. ------------------------------------------------------------------------ Italian Home For Comprehensive Care for $12,500.00 Children Inc. Children ------------------------------------------------------------------------ Jewish Family Service Patient Navigator/Enhanced $20,000.00 of Metrowest Inc. Medical Escort Program ------------------------------------------------------------------------ Jewish Genetic Disease JGDC Website and Social Media $5,000.00 Consortium (JGDC) Rebuild Phase Two and Brochure Update ------------------------------------------------------------------------ Jewish Genetic Diseases Our Heritage and our Health-- $975.00 Center of Greater Ashkenazi Jewish Genetic Phoenix Disease and the Founder Effect ------------------------------------------------------------------------ Just-A-Start Just-A-Start Biomedical $25,000.00 Corporation Careers Program ------------------------------------------------------------------------ Just-A-Start Biomedical Careers Program (& $25,000.00 Corporation Mass Bio Membership) ------------------------------------------------------------------------ Kansas University Fellowship Program $75,000.00 Endowment Association ------------------------------------------------------------------------ Knect365 US, Inc. Selections from DISORDER the $15,000.00 Rare Disease Film Festival at Biotech Week Boston ------------------------------------------------------------------------ Kometa Serbian Volunteer Match $1,000.00 Childrens Program Inc. ------------------------------------------------------------------------ Life Science Cares Inc. 2018 Impact Breakfast $10,000.00 ------------------------------------------------------------------------ Little Brothers/Friends Medical Escort Program $5,000.00 of the Elderly ------------------------------------------------------------------------ Louisiana Association Congress Sponsorship $5,285.00 of Health Plans ------------------------------------------------------------------------ Lycee International De Fundraiser Event $10,000.00 Boston International School of Boston Inc. ------------------------------------------------------------------------ Lysosomal and Rare Fellowship Program $75,000.00 Disorders Research and Treatment Center Inc. ------------------------------------------------------------------------ Lysosomal and Rare Fellowship Program $75,000.00 Disorders Research and Treatment Center Inc. ------------------------------------------------------------------------ Magellan Rx Management Congress Sponsorship $7,500.00 Inc. ------------------------------------------------------------------------ Margaret Fuller Margaret Fuller Neighborhood $15,000.00 Neighborhood House House Youth Programs ------------------------------------------------------------------------ Mass Insight Education Mass Insight's Advanced $15,000.00 and Research Institute Placement (AP) STEM & Inc English Program ------------------------------------------------------------------------ Massachusetts Bay STEM Mentor Program (SMP) $43,000.00 Community College Foundation ------------------------------------------------------------------------ Massachusetts Congress Sponsorship $100,000.00 Biotechnology Council ------------------------------------------------------------------------ Massachusetts Membership $30,800.00 Biotechnology Council ------------------------------------------------------------------------ Massachusetts Patient Advocacy Summit $10,000.00 Biotechnology Council ------------------------------------------------------------------------ Massachusetts Conference Sponsorship $5,000.00 Biotechnology Education Foundation Inc. ------------------------------------------------------------------------ Massachusetts 2018 Champions for $5,000.00 Biotechnology Biotechnology Education Education Foundation Program Inc. ------------------------------------------------------------------------ Massachusetts Life Sciences Workforce 2018 $5,000.00 Biotechnology Education Foundation Inc. ------------------------------------------------------------------------ Massachusetts MassBioEd Mission $50,000.00 Biotechnology Education Foundation Inc. ------------------------------------------------------------------------ Massachusetts Black 2018 Ida B. Wells Annual $5,000.00 Women Attorneys Awards Event Foundation Inc. ------------------------------------------------------------------------ Massachusetts College Next Generation of Women $10,000.00 of Pharmacy and Health Leaders in STEM Sciences ------------------------------------------------------------------------ Massachusetts Life Massachusetts Next Generation $50,000.00 Sciences Center Initiative (MassNextGen) ------------------------------------------------------------------------ Massachusetts State 2018 Fair Operations & Sanofi $50,000.00 Science and Genzyme Science Award Engineering Fair, Inc. ------------------------------------------------------------------------ Medical Oncology Membership $10,000.00 Association of Southern California, Inc. ------------------------------------------------------------------------ MedStar Health Congress Sponsorship $2,500.00 ------------------------------------------------------------------------ Metrowest Free Medical Access to Women's Health Care $15,000.00 Program Inc. Program ------------------------------------------------------------------------ Michigan Society of Membership $12,000.00 Hematology & Oncology ------------------------------------------------------------------------ Museum of Fine Arts Membership $20,000.00 ------------------------------------------------------------------------ Museum of Science Sanofi Genzyme Teacher $71,520.00 Sabbatical at the Museum of Science Cohort Year 2018/19 ------------------------------------------------------------------------ National Comprehensive 2019 NCCN Global Corporate $15,000.00 Cancer Network Council Membership ------------------------------------------------------------------------ National Comprehensive NCCN 13th Annual Congress: $10,000.00 Cancer Network Hematologic MalignanciesTM: Patient Advocacy Pavilion ------------------------------------------------------------------------ National Organization Congress Sponsorship $3,000.00 of Rheumatology Managers ------------------------------------------------------------------------ National Organization Corporate Membership $30,000.00 of Rheumatology Managers ------------------------------------------------------------------------ National Society of Congress Sponsorship $2,500.00 Genetic Counselors ------------------------------------------------------------------------ National Society of Congress Sponsorship $2,500.00 Genetic Counselors ------------------------------------------------------------------------ National Society of Congress Sponsorship $375.00 Genetic Counselors ------------------------------------------------------------------------ NEHI NEHI's 2018 Innovators in $10,000.00 Health Awards ------------------------------------------------------------------------ New York University-- Fellowship Program $75,000.00 Langone School of Medicine ------------------------------------------------------------------------ NJ Sharing Network Congress Sponsorship $5,000.00 ------------------------------------------------------------------------ NJ Society of Oncology Membership $5,000.00 Managers ------------------------------------------------------------------------ Nora's Home Congress Sponsorship $5,000.00 ------------------------------------------------------------------------ North Carolina Oncology Membership $5,000.00 Management Society ------------------------------------------------------------------------ Northeastern University Community Student Scholarship $4,000.00 Program ------------------------------------------------------------------------ Northern California Congress Sponsorship $10,000.00 Rheumatology Society ------------------------------------------------------------------------ Norton Healthcare 2018 Neuroscience Expo $5,000.00 Foundation, Inc. ------------------------------------------------------------------------ Norton Healthcare 2018 Celebrating MS $5,000.00 Foundation, Inc. Innovations ------------------------------------------------------------------------ NSGC Congress Sponsorship $6,600.00 ------------------------------------------------------------------------ Ohio Hematology Membership $5,000.00 Oncology Society ------------------------------------------------------------------------ Operation Warm Inc. 2018 Boston Coat Program $20,000.00 ------------------------------------------------------------------------ Organ Donation & 2018 Corporate Sponsorship $5,000.00 Transplantation Alliance ------------------------------------------------------------------------ Pan American League of Congress Sponsorship $131,750.00 Associations for Rheumatology ------------------------------------------------------------------------ PCMA Pharmaceutical Congress Sponsorship $56,000.00 Care Management Association ------------------------------------------------------------------------ PCMA Pharmaceutical Congress Sponsorship $50,000.00 Care Management Association ------------------------------------------------------------------------ PCMA Pharmaceutical Congress Sponsorship $36,000.00 Care Management Association ------------------------------------------------------------------------ PCMA Pharmaceutical Congress Sponsorship $50,000.00 Care Management Association ------------------------------------------------------------------------ Peer Health Exchange Peer Health Exchange: $5,000.00 Inc. Empowering Boston's Young People to Make Healthy Decisions ------------------------------------------------------------------------ Pennsylvania Congress Sponsorship $10,000.00 Rheumatology Society ------------------------------------------------------------------------ Perkins School for the Technology for Success in $20,000.00 Blind STEM Learning ------------------------------------------------------------------------ Philadelphia Rheumatism Membership $1,000.00 Society ------------------------------------------------------------------------ Phillips Brooks House Bridges Food Science and $3,000.00 Association Physical Fitness Workshop Incorporated ------------------------------------------------------------------------ Phoenix Rheumatology Congress Sponsorship $10,000.00 Association ------------------------------------------------------------------------ Phoenix Rheumatology Congress Sponsorship $30,000.00 Association ------------------------------------------------------------------------ Phoenix Rheumatology Membership $10,000.00 Association ------------------------------------------------------------------------ Premier Oncology Membership $5,000.00 Hematology Management Society ------------------------------------------------------------------------ Premier Oncology Membership $5,000.00 Hematology Management Society ------------------------------------------------------------------------ Premier Specialty Congress Sponsorship $15,000.00 Network ------------------------------------------------------------------------ President and Fellows The Family Van: Culturally- $50,000.00 of Harvard College Competent Care for All ------------------------------------------------------------------------ President and Fellows The Family Van: Increasing $50,000.00 of Harvard College Healthcare Access to Everyone ------------------------------------------------------------------------ Pri-Med Institute Congress Sponsorship $66,750.00 ------------------------------------------------------------------------ Pro Player Foundation Patient Education and $5,000.00 Awareness Program ------------------------------------------------------------------------ Pro Player Foundation Patient Education and $5,000.00 Awareness Program ------------------------------------------------------------------------ Project Just Because, 211 Domestic Abuse/Emergency $10,000.00 Inc. Program & Keep A Family Warm Program ------------------------------------------------------------------------ Prostate Cancer Academy Congress Sponsorship $7,500.00 ------------------------------------------------------------------------ Read to a Child, Inc. Read to a Child's Lunchtime $5,000.00 Reading Program ------------------------------------------------------------------------ Regents of the Fellowship Program $75,000.00 University of California ------------------------------------------------------------------------ Regents of the Lysosomal Storage Diseases $57,059.40 University of Patient and Family California Educational Grant ------------------------------------------------------------------------ Regents of the Fellowship Program $75,000.00 University of Michigan ------------------------------------------------------------------------ Regents of the Fellowship Program $75,000.00 University of Minnesota ------------------------------------------------------------------------ Rheumatology Congress Sponsorship $7,500.00 Association of Iowa ------------------------------------------------------------------------ Rheumatology Congress Sponsorship $20,000.00 Association of Iowa ------------------------------------------------------------------------ Rheumatology Congress Sponsorship $10,000.00 Association of Minnesota and the Dakotas ------------------------------------------------------------------------ Rheumatology Congress Sponsorship $10,000.00 Association of Nevada ------------------------------------------------------------------------ Rheumatology Nurses Congress Sponsorship $2,000.00 Society ------------------------------------------------------------------------ Rheumatology Nurses Congress Sponsorship $45,000.00 Society ------------------------------------------------------------------------ Rheumatology Nurses Congress Sponsorship $3,655.00 Society ------------------------------------------------------------------------ Rheumatology Nurses Congress Sponsorship $33,575.00 Society ------------------------------------------------------------------------ Rheumatology Nurses Congress Sponsorship $1,700.00 Society ------------------------------------------------------------------------ Rheumatology Nurses National Advocacy Sponsorship $50,000.00 Society ------------------------------------------------------------------------ Rheumatology Nurses Speed Advocacy Session of the $7,500.00 Society RNS Advocacy Experience Day ------------------------------------------------------------------------ Rheumatology Nurses Corporate Sponsorship $50,000.00 Society ------------------------------------------------------------------------ Rhode Island Diabetes & Congress Sponsorship $750.00 Endocrine Society ------------------------------------------------------------------------ Run for Dad American Run for Dad $3,000.00 Cancer Society ------------------------------------------------------------------------ S S Cosmas & Damian 92nd Annual Feast of S.S. $2,500.00 Society Inc. Cosmas and Damian ------------------------------------------------------------------------ Samaritans, Inc. Youth Suicide Prevention $25,000.00 Services ------------------------------------------------------------------------ Scholarship America, Chart Your Own Course $32,250.00 Inc. Scholarship Program ------------------------------------------------------------------------ Scholarship America, Sanofi Genzyme TORCH Awards $11,600.00 Inc. program ------------------------------------------------------------------------ Science Club For Girls Science Clubs and Junior $10,000.00 Inc. Mentors Program ------------------------------------------------------------------------ Science From Scientists In-School Module-Based (ISMB) $30,000.00 Inc. STEM Enrichment Program for Boston Public Schools 2017- 18 ------------------------------------------------------------------------ Science From Scientists In-School Module-Based (ISMB) $30,000.00 Inc. STEM Enrichment Program for Boston Public Schools 2018- 19 ------------------------------------------------------------------------ Society for Congress Sponsorship $20,000.00 Investigative Dermatology ------------------------------------------------------------------------ Southern Oncology Membership $5,000.00 Association of Practices ------------------------------------------------------------------------ Southern Regional Congress Sponsorship $2,000.00 Genetics Group (SERGG) ------------------------------------------------------------------------ Special Olympics 2018 Bio-Ball $2,500.00 Massachusetts Inc. ------------------------------------------------------------------------ Special Olympics Special Olympics $7,500.00 Massachusetts Inc. Massachusetts Shrewsbury Basketball Team to Compete at Special Olympics World Games in Abu Dhabi ------------------------------------------------------------------------ Sportsmen's Tennis & School to Sportsmen's Program $15,000.00 Enrichment Center ------------------------------------------------------------------------ St. Francis House Triage Program $10,000.00 ------------------------------------------------------------------------ St. Mary's Center for Women@Work Plus $15,000.00 Women and Children ------------------------------------------------------------------------ State of Texas Congress Sponsorship $40,000.00 Association of Rheumatologists ------------------------------------------------------------------------ State of Texas Congress Sponsorship $40,000.00 Association of Rheumatologists ------------------------------------------------------------------------ The Administrators of NOLA Bluedoo Run/Walk/ $7,500.00 the Tulane Education Celebration for Prostate Fund on behalf of Cancer Research Tulane University Health Sciences Center, CCE ------------------------------------------------------------------------ The American Society of Congress Sponsorship $10,000.00 Hematology ------------------------------------------------------------------------ The American Society of Congress Sponsorship $3,150.00 Hematology ------------------------------------------------------------------------ The Boston Home, Inc. B.Fit! Socialization and $18,000.00 Wellness Day Program ------------------------------------------------------------------------ The Community Art Community Art Center Youth $15,000.00 Center Programming ------------------------------------------------------------------------ The Community Art Community Art Center School $15,000.00 Center Age Child Care and Teen Programs ------------------------------------------------------------------------ The Discovery Museums Sanofi Genzyme Discovery $15,000.00 Science 2018 ------------------------------------------------------------------------ The Discovery Museums Fundraiser Event $5,000.00 ------------------------------------------------------------------------ The Discovery Museums Discovery Science: Framingham $15,000.00 and Waltham ------------------------------------------------------------------------ The Endocrine Society Congress Sponsorship $3,995.00 ------------------------------------------------------------------------ The Forsyth Institute Mobile Dental Program Service $10,000.00 to the Youth on Fire Shelter in Cambridge ------------------------------------------------------------------------ The Greater Boston Food General Operating Support $30,000.00 Bank Inc. ------------------------------------------------------------------------ The Greater Boston Food Volunteer Match $1,000.00 Bank Inc. ------------------------------------------------------------------------ The Greater Boston Food Volunteer Match $1,000.00 Bank Inc. ------------------------------------------------------------------------ The Greater Boston Food Emergency Food Distribution $30,000.00 Bank Inc. Across Eastern Massachusetts ------------------------------------------------------------------------ The Jewish P.O.C.E.T. Congress Sponsorship $2,500.00 ------------------------------------------------------------------------ The Massachusetts Everyday Amazing Race $5,000.00 General Hospital ------------------------------------------------------------------------ The McCourt Foundation Educational Update $20,000.00 ------------------------------------------------------------------------ The McCourt Foundation Tour de South Shore Athletic $5,000.00 Festival ------------------------------------------------------------------------ The McCourt Foundation MS Educational Update for $20,000.00 Patients, Caregivers and Family Members ------------------------------------------------------------------------ The Oak Clinic 2018 Oak Clinic Acorn Run $4,500.00 ------------------------------------------------------------------------ The Oak Clinic Oak Clinic's Marvelous $15,000.00 Monday's Wellness Programs ------------------------------------------------------------------------ The Oak Clinic 2018 Oak Clinic Diamond Run $5,000.00 ------------------------------------------------------------------------ The Posse Foundation Posse Boston $25,000.00 Inc. ------------------------------------------------------------------------ The Possible Project The Possible Project 2018 $10,000.00 Event Series ------------------------------------------------------------------------ The Regents of the Fellowship Program $75,000.00 University of California, Irvine ------------------------------------------------------------------------ The Regents of the Fellowship Program $75,000.00 University of California, Los Angeles ------------------------------------------------------------------------ The Salvation Army Volunteer Match $2,000.00 ------------------------------------------------------------------------ The Salvation Army Volunteer Match $6,000.00 ------------------------------------------------------------------------ The UCLA Foundation The UCLA Fabry Disease $2,500.00 Program ------------------------------------------------------------------------ Thompson Island Outward Connections Program $15,000.00 Bound Education Center Inc. ------------------------------------------------------------------------ Thompson Island Outward 2018 Thompson Island 4k Trail $5,000.00 Bound Education Center Run Inc. ------------------------------------------------------------------------ Trustees of Boston Community Student Scholarship $4,000.00 University Program ------------------------------------------------------------------------ Trustees of Boston Community Student Scholarship $825.00 University Program ------------------------------------------------------------------------ Trustees of the The 19th International $50,000.00 University of Vasculitis & ANCA Workshop Pennsylvania ------------------------------------------------------------------------ Tutoring Plus of STEAM Programming $5,000.00 Cambridge, Inc. ------------------------------------------------------------------------ Tutoring Plus of Elementary and Middle School $12,500.00 Cambridge, Inc. Programs ------------------------------------------------------------------------ UAB Division of Fellowship Program $75,000.00 Nephrology Attn: Jennifer Clendenin ------------------------------------------------------------------------ UConn Health Congress Sponsorship $500.00 ------------------------------------------------------------------------ United Arizona Congress Sponsorship $25,000.00 Rheumatology Alliance ------------------------------------------------------------------------ United Network For Congress Sponsorship $9,100.00 Organ Sharing ------------------------------------------------------------------------ United Network For Congress Sponsorship $6,000.00 Organ Sharing ------------------------------------------------------------------------ United Network For Congress Sponsorship $8,000.00 Organ Sharing ------------------------------------------------------------------------ United Rheumatology LLC Congress Sponsorship $135,000.00 ------------------------------------------------------------------------ United Way of Tri- Volunteer Match $1,000.00 County ------------------------------------------------------------------------ University of Alabama Fellowship Program $75,000.00 at Birmingham ------------------------------------------------------------------------ University of Chicago Congress Sponsorship $15,000.00 Hospitals ------------------------------------------------------------------------ University of Colorado Congress Sponsorship $20,000.00 Anschutz Medical Campus ------------------------------------------------------------------------ University of Florida Fellowship Program $75,000.00 Foundation Inc. ------------------------------------------------------------------------ University of Florida Fellowship Program $74,900.00 Foundation Inc. ------------------------------------------------------------------------ University of Illinois Congress Sponsorship $10,000.00 at Chicago ------------------------------------------------------------------------ University of Congress Sponsorship $10,000.00 Louisville ------------------------------------------------------------------------ University of Student Success Program, $200,000.00 Massachusetts UMass Boston, College of Foundation Inc. Science and Mathematics ------------------------------------------------------------------------ University of TORCH award donations $5,000.00 Mississippi Foundation ------------------------------------------------------------------------ Uplifting Athletes Inc. Leadership Development $38,000.00 Conference/Organizational Support ------------------------------------------------------------------------ Uplifting Athletes Inc. 2019 Uplifting Athletes Young $20,000.00 Investigator Draft ------------------------------------------------------------------------ Uplifting Athletes Inc. Young Investigator Draft $5,000.00 ------------------------------------------------------------------------ Vanderbilt University Fellowship Program $75,000.00 School of Medicine ------------------------------------------------------------------------ VNA Care Hospice Inc. Elizabeth Evarts de Rham $5,000.00 Hospice Home at Chilton Street ------------------------------------------------------------------------ Wade Institute for Summer Professional $20,000.00 Science Education Development STEM Institutes for teachers ------------------------------------------------------------------------ Wade Institute for Summer Professional $20,000.00 Science Education Development Institutes for Science Teachers 2019 ------------------------------------------------------------------------ Washington State Membership $5,000.00 Medical Oncology Society ------------------------------------------------------------------------ Wentworth Institute of Community Student Scholarship $4,000.00 Technology Program ------------------------------------------------------------------------ West End House Boys and Volunteer Match $1,000.00 Girls Club ------------------------------------------------------------------------ West End House Boys and Volunteer Match $1,000.00 Girls Club ------------------------------------------------------------------------ West End House Boys and West End House Expect More $24,609.00 Girls Club Campaign: MakerZone ------------------------------------------------------------------------ West End House Boys and West End House Annual $25,000.00 Girls Club Celebration ------------------------------------------------------------------------ West End House Boys and West End House Annual $50,000.00 Girls Club Celebration ------------------------------------------------------------------------ Western States Regional Congress Sponsorship $18,000.00 Hemophilia Network ------------------------------------------------------------------------ Wheelchairs 4 Kids Let's Roll Program $10,000.00 ------------------------------------------------------------------------ Whitehead Institute for Expedition: Bio 2019 $10,000.00 Biomedical Research ------------------------------------------------------------------------ Wisconsin Rheumatology Congress Sponsorship $10,000.00 Association ------------------------------------------------------------------------ Women's Dermatologic Congress Sponsorship $2,500.00 Society ------------------------------------------------------------------------ Women's Lunch Place Healthy Meals Program $45,000.00 ------------------------------------------------------------------------ WORLD Symposium Congress Sponsorship $1,000.00 ------------------------------------------------------------------------ WORLD Symposium Congress Sponsorship $1,000.00 ------------------------------------------------------------------------ WORLD Symposium Congress Sponsorship $1,000.00 ------------------------------------------------------------------------ WORLD Symposium Congress Sponsorship $67,000.00 ------------------------------------------------------------------------ WORLD Symposium Congress Sponsorship $110,000.00 ------------------------------------------------------------------------ WORLD Symposium Congress Sponsorship $5,000.00 ------------------------------------------------------------------------ WORLD Symposium Congress Sponsorship $50,000.00 ------------------------------------------------------------------------ WORLD Symposium Congress Sponsorship $60,000.00 ------------------------------------------------------------------------ WORLD Symposium Congress Sponsorship $35,000.00 ------------------------------------------------------------------------ WORLD Symposium Congress Sponsorship $35,000.00 ------------------------------------------------------------------------ WORLD Symposium Congress Sponsorship $50,000.00 ------------------------------------------------------------------------ WORLD Symposium Congress Sponsorship $50,000.00 ------------------------------------------------------------------------ WORLDSymposia Congress Sponsorship $5,250.00 ------------------------------------------------------------------------ WORLDSymposia Congress Sponsorship $45,000.00 ------------------------------------------------------------------------ WriteBoston Aligning and Elevating $18,000.00 Literacy Instruction across the Chelsea Public Schools ------------------------------------------------------------------------ YMCA of Greater Boston Scholarships for Low-Income $15,000.00 Allston-Brighton Children ------------------------------------------------------------------------ ziMS Foundation 2018 ZIMS Strike Down MS Bowl- $5,000.00 A-Thon ------------------------------------------------------------------------ Proposal Type Project Name Legal Name Amount Corporate Transplantation Critical Path $55,000.00 Membership Therapeutics Institute Membership Corporate Corporate Endocrine Society $11,000.00 Membership Membership Corporate Corporate Colorado Business $5,000.00 Membership Membership Group on Health Corporate Corporate Rheumatology $200,000.00 Membership Membership Research Foundation Corporate Corporate National $25,000.00 Membership Membership Governors Association Corporate Corporate National $5,000.00 Membership Membership Conference of Insurance Legislato Corporate CEVR Membership Tufts Medical $35,000.00 Membership Center Corporate Corporate American $20,000.00 Membership Membership Association for Cancer Research Corporate Corporate American $20,000.00 Membership Membership Association for Cancer Research Corporate Corporate American $25,000.00 Membership Membership Association of Diabetes Educator Corporate Corporate AMGA Foundation $15,000.00 Membership Membership Inc. Corporate 2018 NEHI NEHI $75,000.00 Membership Membership Corporate 2018 Corporate National Kidney $10,000.00 Membership Membership Foundation, Inc. Corporate Corporate The Partnership $19,000.00 Membership Membership Dues for Quality 2018 Medical Donati Corporate STOP Obesity George Washington $25,000.00 Membership Alliance University's STOP Obes Corporate Premium Texas Business $15,000.00 Membership Membership Group on Health Corporate Health University of $50,000.00 Membership Organization Louisville Corporate School of Public Membership Health Corporate Corporate American $20,000.00 Membership Membership Association of Nurse Practitioner Corporate Corporate Georgia Chamber $750.00 Membership Membership of Commerce Corporate Corporate American $20,000.00 Membership Membership Association of Clinical Endocrinol Corporate Corporate National Business $16,500.00 Membership Membership Group on Health Corporate PBSM Corporate National Business $15,000.00 Membership Membership Group on Health Corporate Membership Dues Florida Chamber $2,000.00 Membership of Commerce, Inc. Corporate 2018 Membership Buyers Health $10,000.00 Membership Care Action Group Corporate Chamber of Montana Chamber $280.00 Membership Commerce Dues of Commerce Corporate Corporate Business for $33,000.00 Membership Membership Social Responsibility Corporate 2018 ACCP Annual Association of $6,250.00 Membership Membership Corporate Contributions Pro Corporate Corporate Society of $2,500.00 Membership Membership Toxicologic Pathology Corporate Corporate Healthcare $45,000.00 Membership Membership Distribution Alliance HDA Corporate Tufts CSDD Tufts Center for $15,000.00 Membership the Study of Drug Developm Corporate Affiliate Massachusetts $2,500.00 Membership Membership Dues Association of Health Plans Corporate Corporate National Health $32,000.00 Membership Membership Council Corporate Corporate Illinois $2,500.00 Membership Membership Manufacturers' Association Corporate NASPA 2018 NASPA $5,000.00 Membership Associate Member Dues Corporate Corporate National LGBT $7,500.00 Membership Membership 2018 Chamber of Commerce Corporate Corporate National LGBT $7,500.00 Membership Membership 2018 Chamber of Commerce Corporate Corporate International $20,000.00 Membership Membership Society for Medical Publicatio Corporate ACPA Corporate American Chronic $10,000.00 Membership Membership Pain Association Corporate Corporate Pharmaceutical $397,832.00 Membership Membership Research and Manufacture Corporate Corporate Pharmaceutical - Membership Memberhsip Research and Manufacture Corporate Women's Heart Tides Center $75,000.00 Membership Alliance Mebership Corporate Corporate College Diabetes $25,000.00 Membership Membership Network Inc. Corporate Corp. AIM--Associated $10,000.00 Membership Industries of Massachuset Corporate NLGA Corporate National Lt. $10,000.00 Membership Membership Governors Association Corporate Corporate Ohio Chamber of $1,700.00 Membership Membership Commerce Corporate Corporate Somerset Health $2,500.00 Membership Membership Care Foundation Corporate Corporate Academy of $10,000.00 Membership Membership Managed Care Pharmacy Corporate Corporate HealthCare $5,000.00 Membership Membership Institute of NJ Corporate DA4S Corporate Diversity $700.00 Membership Membership Alliance for Science, Inc. Corporate Corporate Healthcare $23,500.00 Membership Membership Businesswomen's Association Corporate National Quality National Quality $39,400.00 Membership Forum Membership Forum Corporate WPEO Corporate Women President $5,000.00 Membership Membership Educational Organization Corporate Corporate Minnesota Society $6,000.00 Membership Membership of Health-System Pharm Corporate Corporate The Medical Alley $2,000.00 Membership Membership Association Corporate 2018 Membership New York & New $6,500.00 Membership Jersey Minority Supplier D Corporate Corporate Pittsburgh $3,450.00 Membership Membership Business Group on Health Corporate GDAHC Corporate Greater Detroit $7,000.00 Membership Membership Area Health Council, Inc. Corporate Ruby Annual US Business $7,500.00 Membership Membership Leadership Network Corporate Ruby Annual US Business $7,500.00 Membership Membership Leadership Network Corporate 2018 Corporate Physician $20,000.00 Membership Dues Assistant Foundation of the Americas Corporate 2018 Somerset Somerset County $15,000.00 Membership County Business Business Partnership dues Partnership Corporate Annual Membership Women in $20,000.00 Membership Government Foundation, Inc. Corporate CLSA Sustaining California Life $76,000.00 Membership Membership Sciences Association Corporate NaVOBA corporate NaVOBA--National $15,000.00 Membership membership Veteran Owned Busines Corporate Corporate Intellectual $26,800.00 Membership Membership Property Owners Association Corporate Annual Membership Michigan Primary $5,000.00 Membership Care Consortium Corporate Annual Membership National Alliance $15,000.00 Membership of Healthcare Purchaser Corporate Annual Membership ISPOR $15,000.00 Membership Corporate Corporate The Antibody $10,000.00 Membership Membership Society Corporate Corporate Michigan $2,500.00 Membership Membership Association of Health Corporate Corporate Life Science $1,500.00 Membership Membership Tennessee Corporate 2018 Corporate Association of $75,000.00 Membership Membership Community Cancer Centers Corporate Corporate Texas Association $5,000.00 Membership Membership of Manufacturers Corporate Annual Membership JDRF $30,000.00 Membership International Corporate Corporate AMDA--The Sociery $2,584.00 Membership Membership for Post-Acute and Long Corporate Corporate Texas Healthcare $5,000.00 Membership Membership and Bioscience Institute Corporate Corporate BioForward $3,000.00 Membership Membership Corporate Annual Membership National $224,000.00 Membership Association of Manufacturers Corporate 2018 Business The Health $450.00 Membership Partner Collaborative Membership Corporate OFII 2018 Organization for $17,500.00 Membership Membership Dues International Investment Corporate AMA Foundation American Medical $20,000.00 Membership dues Association Foundation Corporate Corporate National $200,000.00 Membership Membership Dues Pharmaceutical Council Corporate Corporate National $200,000.00 Membership Membership Dues Pharmaceutical Council Corporate Corporate National $50,000.00 Membership Membership Dues Pharmaceutical Council Corporate Biocom Membership Biocom $15,000.00 Membership Dues Corporate 2018 Preferred BIONJ Inc. $30,000.00 Membership Membership Corporate 2018 Membership Healthcare $200,000.00 Membership Dues Leadership Council Corporate Corporate Oregon Business & $1,500.00 Membership Membership Industry Association Corporate Membership Dues American Society $30,000.00 Membership of Transplantation Corporate Patients Count Milken Institute $50,000.00 Membership Membership Dues Corporate Membership Dues Rheumatology $200,000.00 Membership Research Foundation Corporate Membership Dues The Kansas $993.00 Membership Chamber Corporate Membership Dues Lehigh Valley $1,500.00 Membership Business Coalition on Healthcare Corporate 2018 BIO Biotechnology $718,851.00 Membership Membership Innovation Organization Corporate 2018 Membership Northeast $10,500.00 Membership Dues Business Group on Health Corporate Corporate Indiana Chamber $650.00 Membership Membership of Commerce Corporate Corporate American Society $35,000.00 Membership Membership Dues of Hematology Corporate Corporate HealthCare 21 $2,750.00 Membership Membership Business Coalition Corporate MichiBio Michigan $1,500.00 Membership Membership Biosciences Industry Association Corporate Membership Dues Virginia Bio $2,300.00 Membership Corporate Corporate American $50,000.00 Membership Membership Foundation for Women's Health Corporate PSTC Corporate Critical Path $35,000.00 Membership Membership Institute Corporate Corporate Research!America $15,000.00 Membership Membership Dues Corporate Membership Dues ILSI Health and $15,000.00 Membership Environmental Health Instit Corporate Membership Dues ILSI Health and $82,971.00 Membership Environmental Health Instit Corporate Membership Dues Washington Health $6,930.00 Membership Alliance Corporate Membership Dues Employers Health $1,000.00 Membership Coalition, Inc. Corporate Membership Dues State Legislative $35,000.00 Membership Leaders Foundation, Inc. Corporate Associate Alliance for $50,000.00 Membership Sustaining Patient Access Membership Dues Corporate 2018 NewYorkBIO NewYorkBIO $2,500.00 Membership Membership Corporate Membership Michigan Chamber $1,950.00 Membership Renewal of Commerce Corporate CAHF Associate CA Assn of Health $1,200.00 Membership Membership Facilities Renewal Corporate 2018 Memebership Alliance for a $20,000.00 Membership Stronger FDA Corporate Industry Advisory The Foundation $25,000.00 Membership Board for Post-Acute & Long-Term Corporate DTA Membership Digital $75,000.00 Membership Therapeutics Alliance Corporate Corporate Public Affairs $12,900.00 Membership Membership Council Renewal Corporate 2018 IPAC Diabetes $15,000.00 Membership membership Education and Camping Associatio Corporate Annual Membership Evidence for $100,000.00 Membership Health Care Improvement d/b Corporate Consortium for National Academy $100,000.00 Membership Value and of Sciences Science Membership Corporate HRPA Membership HR Policy $15,000.00 Membership Association Corporate CPR Membership International $10,000.00 Membership Institute for Conflict Preventio Corporate Corporate American $100,000.00 Membership Membership Enterprise Institute for Public Policy Corporate Annual Membership Louisiana $1,765.00 Membership Association of Health Plans Corporate Corporate U.S. Capitol $10,000.00 Membership Committee Historical Membership 2018 Society Corporate 2018 Memebership Well-Being $1,000.00 Membership Collaborative of Ohio Corporate 2018 Council Virginia Center $5,000.00 Membership Membership for Health Innovation Corporate Corporate Arkansas State $1,000.00 Membership Membership Chamber of Commerce/AIA Corporate Corporate International $8,000.00 Membership Membership Society for Pharmacoepidemi Corporate AWB Membership Association of $2,500.00 Membership Washington Business Corporate Membership dues Pharmaceutical - Membership Research and Manufacture Corporate Annual Membership Medical $5,000.00 Membership Association of Georgia Corporate Annual Membership New Jersey $5,000.00 Membership Association of Health Plans Corporate Annual Membership CECP $15,000.00 Membership Corporate Corporate Kentuckiana $1,500.00 Membership Membership Health Collaborative Corporate 2018 PQA PQA, Inc. $34,375.00 Membership Membership Dues Corporate 2018 CIBMTR The Medical $30,000.00 Membership Corporate College of Membership Wisconsin, Inc. Corporate Annual Membership American $75,000.00 Membership Thrombosis and Hemostasis Network Corporate Annual Membership Missouri Chamber $1,500.00 Membership of Commerce and Indust Corporate Annual membership Center Forward $20,000.00 Membership Corporate PACH Associate Partnership for $125,000.00 Membership Membership the Advancement of Cardio Corporate HUBZone HUBZone $2,495.00 Membership Contractors Contractors National Council National Council, Inc. Corporate Annual Membership Greater Las Vegas $1,499.50 Membership Chamber of Commerce Corporate GlobalWIN Annual Global Women's $20,000.00 Membership Support Innovation Network Corporate FDLI Membership Food and Drug Law $13,750.00 Membership Institute Corporate Annual Membership Wisconsin $714.00 Membership Manufacturers and Commerce Corporate Annual Membership Midwest Business $8,000.00 Membership Group on Health Corporate Corporate National $25,000.00 Membership Membership Committee for Quality Assurance Corporate Affiliate Partner Central Florida $1,800.00 Membership dues Health Care Coalition Corporate MRCT Clinical Multi Regional $50,000.00 Membership Trials Clinical Trial Membership Center of Brigha Corporate MRCT Bioethics Multi Regional $25,000.00 Membership Membership Clinical Trial Center of Brigha Corporate MOBIO Membership Missouri $1,500.00 Membership 2018 Biotechnology Association Corporate Corporate National Hispanic $25,000.00 Membership Membership Health Foundation Corporate Annual Membership West Virginia $1,320.00 Membership Chamber of Commerce, Inc. Corporate Annual Membership New Jersey $3,000.00 Membership Alliance for Action Corporate Corporate American College $1,500.00 Membership Membership of Toxicology Corporate 2018 Memebership National $9,960.00 Membership Association of Chain Drug Stores Corporate Annual Membership Business Council $3,000.00 Membership of Alabama Corporate Corporate US Pain $20,000.00 Membership Membership Foundation Inc. Corporate Corporate South Carolina $3,000.00 Membership Membership Alliance of Health Plans Corporate Corporate The Oklahoma $2,400.00 Membership Membership State Chamber of Commerc Corporate Corporate American $5,000.00 Membership Membership Legislative Exchange Council Corporate Corporate American $12,000.00 Membership Membership Legislative Exchange Council Corporate Corporate American Society $20,000.00 Membership Membership of Nephrology Corporate Corporate American Society $10,000.00 Membership Membership of Nephrology Corporate Annual Membership Iowa $2,000.00 Membership Dues Biotechnology Association Corporate CHOT Annual University of $50,000.00 Membership Membership Louisville School of Public Health Corporate Corporate Maryland Health $5,000.00 Membership Membership Care Coalition DBA MidAtlantic Corporate Corporate NCSL Foundation $12,500.00 Membership Membership for State Legislatures Corporate Corporate Associated $3,865.00 Membership Membership Industries of Missouri Corporate Annual Associate Derma Care Access $100,000.00 Membership Membership Network Corporate Corporate Wisconsin $3,750.00 Membership Membership Collaborative for Healthcare Quality Corporate Corporate Academy of $15,000.00 Membership Membership Integrative Pain Management Corporate Corporate Association of $3,000.00 Membership Membership Military Surgeons of the Unit Corporate DPAC Corporate Diabetes Patient $25,000.00 Membership Membership Advocacy Coalition Corporate HISCI Membership Health Industry $5,300.00 Membership Distributors Association Corporate CCCC Corporate California $5,000.00 Membership Membership Chronic Care Coalition Corporate Corporate America's $25,000.00 Membership Membership 2018- Physician Groups 2019 Corporate Corporate Integrated $33,450.00 Membership Membership Benefits Institute, Inc. Corporate Corporate Integrated $7,814.00 Membership Membership Benefits Institute, Inc. Corporate Corporate Integrated $8,736.00 Membership Membership Benefits Institute, Inc. Corporate 2019 Affiliate Greater $5,000.00 Membership Membership Dues Philadelphia Business Coalition on Health Corporate Maryland Tech Maryland Tech $1,800.00 Membership Council Council Membership Corporate Gender Parity Healthcare $30,000.00 Membership Collaborative Businesswomen's Membership Association Donations Adult Day Center Visiting Nurse $10,000.00 Expanded Association of Therapeutic Somerset Hills Programing Request Donations SARP Program The Pennsylvania $150,000.00 Support State University Donations Katy's Place The Center For $5,000.00 Child Great Development Expectations Center Inc. Donations Community Operation Jersey $600.00 Outreach to Cares Veterans Donations Sanofi US Seattle $5,000.00 Empowering Life Children's Photo Contest Hospital Foundation Donations Student Support Drexel University $5,000.00 for Drexel Chemical and Biological Engineering Donations XTL Youth Affirmations $2,500.00 Programming--Emp owering Life Winner Donations COTA for CJ T-- COTA Children's $2,500.00 Empowering Life Organ Transplant Winner Associati Donations General Mission The Partnership $10,000.00 Support for Quality Medical Donati Donations Research Training Trustees of The $20,000.00 in University of Pharmacoepidemio Pennsylvania logy Donations Friends of Cancer Friends of Cancer $50,000.00 Research Mission Research Support Donations Cooley Landing Grassroots $25,000.00 Community-Based Ecology Baylands Restoration Project Donations Green Printing Arbor Day $4,944.00 Initiative Foundation Donations Veterans and U.S. Naval $1,000.00 Careers Academy Alumni Association Donations Fellowship Pharmaceutical $270,000.00 Support Research and Manufacture Donations General Mission United Way of $55.00 Support Northern New Jersey Donations 2018 Warrior Operation Warrior $10,000.00 Wishes Program Wishes Foundation Donations General Mission ASTS Foundation $50,000.00 Support Donations General Operating American College $2,500.00 Support of Laboratory Animal Medicine Donations Meals on Wheels Midland Adult $5,000.00 Services Inc. Donations General Operating Washington Legal $30,000.00 Support Foundation Donations Empowering young Junior $50,000.00 people for Achievement of success in STEM New Jersey, Inc. careers Donations Get Active and College Diabetes $12,000.00 Make a Network Inc. Difference Challenge Donations Get Active and Junior $2,500.00 Make a Achievement USA Difference Challenge Donations Get Active & Make Boys & Girls $2,500.00 a Difference Clubs of America Challenge Donations Residential Safe + Sound $10,000.00 Children's Somerset Program Donations Get Active and March of Dimes $8,000.00 Make a Foundation Difference Challenge Donations Healthy Food The Salvation $10,000.00 Pantry Program Army Donations Responding to Direct Relief $25,000.00 California Wildfires Donations Vets4Warrios Rutgers $2,000.00 University Foundation Donations MAP's Domestic Map International $10,000.00 Disaster Relief Prepardness Donations Midland Explores Midland Adult $5,000.00 Community Services Inc. Program Donations MAS Employment Midland Adult $5,000.00 Program Services Inc. Donations Get Active and Wounded Warrior $40,000.00 Make a Project, Inc. Difference Challenge Donations Advancing Students 2 $250,000.00 Authentic STEM Science Education Donations Success By 6 with United Way of $37,000.00 Scholarship Northern New Support and STEM Jersey Enhancement Donations Get Active and National Alliance $2,500.00 Make A for Caregiving Difference Challenge Donations General Operating Food Bank of $25,000.00 Support Somerset County Inc. Donations Corporate Work- Cristo Rey Newark $60,000.00 Study Program High School Corp. Donations U.S. Disaster Americares $25,000.00 Assitance Donations LGBT Staff Somerset Health $7,000.00 Sensitivity Care Foundation Training Donations US Disaster Heart To Heart $25,000.00 Readiness & International Response Inc. Donations U.S. Emergency Direct Relief $25,000.00 Preparedness and Response Donations Empowering Inner Sheltered Yoga $5,000.00 City Kids Through Yoga & Meditation Donations Comprehensive NJ Sharing $5,000.00 Family Support Network Foundation Donations NCCN Foundation NCCN Foundation $25,000.00 Patient Advocacy Collaboration Donations Advocacy and Deirdre O'Brien $5,000.00 Forensic Child Advocacy Interviewing of Center Inc. Child Victims of Abuse Donations Genearl Operating Camp Quality USA $10,000.00 Support dba Camp Quality NJ Donations General Operating Jersey Battered $5,000.00 Women's Service, Inc. Donations Trainee Society for $25,000.00 Professional Neuroscience Development Awards Donations Project Self Family Promise of $10,000.00 Sufficiency--San Monroe County ofi in our Communities Donations Americares Americares $5,000.00 Airlift Benefit Donations Get Active and Dress for Success $2,500.00 Make a Northern New Difference Jersey--10 Challenge Donations Young Scholars NJ SEEDS $10,000.00 Program Donations Vets4Warriors Rutgers $10,000.00 University Foundation Donations Foundations of Dress for Success $10,000.00 Success Northern New Jersey--10 Donations US Disaster Heart To Heart $25,000.00 Relief--Hurrican International e Michael Inc. Donations Hurricane Michael Direct Relief $50,000.00 Response Donations Hunterdon County Hunterdon $10,000.00 Food Back Pack Healthcare Program Foundation Donations General Operating Hyacinth $10,000.00 Support Foundation: A New Jersey Nonprofit Donations HSF General Hispanic $5,000.00 Operating Scholarship Fund Support Donations Hurricane Michael Americares $25,000.00 Response Donations General Operating Good Grief Inc. $5,000.00 Support Donations General Operating Deirdre O'Brien $5,000.00 Support Child Advocacy Center Inc. Donations Valhalla's Hope Valhalla Veterans $10,000.00 Services Donations Residential Community Hope, $25,000.00 Recovery Inc. Programs for Homeless Veterans and Dis Donations Sanofi Corporate Raritan Valley $10,000.00 Mentor Program Community at RVCC College Foundat Donations PRIDE Connect Hyacinth $3,500.00 Project Support Foundation: A New Jersey Nonprofit Donations Trevor's Life- Trevor Project $3,500.00 Saving Programs Inc. for LGBTQ Youth Donations General Operating Junior $5,000.00 Support Achievement of Northeastern Pennsylvania Donations Camp Nejeda: Camp Nejeda $10,000.00 Helping Kids Foundation with type 1 diabetes live happier Donations Advocacy Program Deirdre O'Brien $5,000.00 for Child Child Advocacy Victims of Abuse Center Inc. and or Neglect Donations California Direct Relief $100,000.00 Wildfires Donations SP 2018 UW United Way of $86,982.00 Campaign Match Monroe County Donations Vets4Warrios Rutgers $4,000.00 University Foundation Donations Support4Families: Cancer Support $15,000.00 Teens Connect Community School-Based Central Support Group Donations Supporting Students 2 $25,000.00 Environmental Science Science for High School Students Donations Health for Covenant House $25,000.00 Homeless Youth New Jersey Inc. Donations Medical Home Children's Health $198,000.00 Initiative 2019 Fund Donations Serving Local Matheny School $10,000.00 Patients With and Hospital Disabilities Inc. Donations Matheny School Matheny School $10,000.00 STEM program and Hospital Inc. Donations Support4Families: Cancer Support $5,000.00 Strengthening Community Our Schools Central Donations Food, Health and The Community $25,000.00 Hope: An Answer Food Bank of New to Diabetes (FHH Jersey Diabetes) Donations Camp Quality USA Camp Quality USA $10,000.00 dba Camp Quality dba Camp Quality NJ NJ Donations General Operating Visiting Nurse $10,000.00 Support Association of Somerset Hills Donations Steeple Chase Somerset Health $100,000.00 Cancer Center Care Foundation Patient Assistance Fund Donations General Hyacinth $10,000.00 Operational Foundation: A Support New Jersey Nonprofit Donations Healthier Somerset Health $10,000.00 Somerset Care Foundation Donations HSF STEM Summit Hispanic $50,000.00 Scholarship Fund Donations Nights of Support Good Grief Inc. $10,000.00 Program Donations General Operating Dress for Success $10,000.00 Support Northern New Jersey--10 Donations Trevor's Life- Boys & Girls $10,000.00 Saving Programs Clubs of Union for LGBTQ Youth County Donations Camp Nejeda: Camp Nejeda $10,000.00 Education and Foundation Empowerment for Children Donations Vets4Warriors Rutgers $10,000.00 University Foundation Donations HSF Scholarship Hispanic $50,000.00 Fund Scholarship Fund Donations General Operating NJ SEEDS $10,000.00 Support for NJ SEEDS Donations Banco de Banco de $25,000.00 ALimentos de Alimentos de Puerto Rico Puerto Rico LOR BCCNS Patient BCCNS Alliance $25,000.00 Project LOR Patient Patients Rising, $10,000.00 Engagement Inc. Sponsorship LOR Patient Education Taking Control of $40,000.00 Diabetes Your Diabetes Conferences and Health Fairs LOR Biological California $15,000.00 Research Institute of Symposium Technology LOR Patient Skin American Cancer $200,000.00 Cancer Education Society and Awareness LOR Populatoin Health Thomas Jefferson $60,000.00 Leadership University Series LOR nPOD Annual University of $15,000.00 Meeting Florida LOR Diabetes Scholars Diabetes Scholars $10,000.00 Foundation Foundation College Scholarships LOR 2018 Annual Health Action $4,700.00 Symposium and Council Conference LOR Western Atrial University of $50,000.00 Fibrillation Utah Symposium 2018 LOR Gordon Research Gordon Research $5,000.00 Conference on Conferences Myelin LOR Cell Culture Engineering $5,000.00 Engineering XVI Conferences Conference International LOR 2018 Alliance Alliance for $20,000.00 Industry Summitt Continuing Education in the Health Sciences LOR Symposium on Drug Massachusetts $8,000.00 Delivery Systems Institute of Technology LOR 2nd Annual EPIC Children's $10,000.00 Diabetes Diabetes Conference Foundation LOR ASN 48th Annual American Society $2,500.00 Meeting for Neurochemistry LOR 2018 BIO Biotechnology $334,500.00 International Innovation Convention Organization LOR FOCIS 2018 Annual Federation of $25,000.00 Meeting Clinical Immunology Societies LOR 2018 BIO Europe Biotechnology $22,500.00 Spring Innovation Organization LOR 2018 BIO Europe Biotechnology $22,500.00 Fall Innovation Organization LOR Annual Healthcare MIT Sloan $5,000.00 Conference Healthcare Conference and Club LOR SOT 2018 Annual Society of $10,000.00 Meeting Toxicology LOR 2018 Public American $20,000.00 Policy Forum Association of Diabetes Educator LOR Annual Gala Asian American $20,000.00 Dinner Legal Defense and Educatio LOR JDRF Imagine Gala JDRF $10,000.00 LOR 2018 Advocacy Research!America $25,000.00 Awards Dinner LOR JDRF Government JDRF $50,000.00 Day International LOR Immune Tolerance Parker Institute $10,000.00 Symposium for Cancer Immunotherapy LOR Annual Forum on National Academy $85,000.00 Drug Discovery of Sciences and Development LOR Biomedical Foundation for $25,000.00 Research Program Biomedical Research LOR Annual Symposium CASSS $2,500.00 of Regulatory and Analytical Science LOR Analytical CASSS $2,500.00 Technologies Symposium LOR 2018 Gordon Gordon Research $3,000.00 Research Conferences Conference on Medicinal Chemistry LOR 2018 AMSSM American Medical $50,000.00 Foundation Society for Research Grant Sports Medicine Award Program LOR Patient National Health $130,000.00 Perspective Council Program LOR Annual Business Waltham Chamber $6,000.00 Meeting of Commerce LOR Barriers of the Gordon Research $5,000.00 CNS Conference Conferences LOR FARE Patient Food Allergy $50,000.00 Registry Research & Education, Inc. LOR Wonder Women: Center for Talent $40,000.00 Flourishing and Innovation Thriving on the Frontiers LOR Early American $55,000.00 Osteoarthritis Orthopaedic and Prevention Society for of OA Sports Medicine Progression LOR Pharmacy Iowa Pharmacy $10,000.00 Leadership Association Training Program Foundation LOR FIU Global Health Florida $95,000.00 Conference International University Board of Trustees LOR 2018 Statewide Florida Health $15,000.00 Cardiac Care Coalition Collaborative LOR 36 Annual JDRF JDRF $2,500.00 Boston Gala International LOR Innovative Preventive $150,000.00 Medicine Cardiovascular Campaign Nurses Association LOR Women and Heart WomenHeart: The $50,000.00 Disease Program National Coalition for Women With Heart Disease LOR Off to College College Diabetes $50,000.00 Sponsorship 2018 Network Inc. LOR Patient Education Diabetes $2,000.00 Diabetes Foundation of Conference Mississippi LOR Division of ACS Division of $3,000.00 Medicinal Medicinal Chemistry Chemistry Program ACS National Meeting LOR Patient Centered National Lipid $16,060.00 Management of Association Dyslipidemia LOR 2018 Annual SMA Families of SMA $5,000.00 Conference DBA Cure SMA LOR 2018 ZERO ZERO--The End of $2,000.00 Prostate Cancer Prostate Cancer Summit LOR DA4S West Coast Diversity $3,000.00 2018 Alliance for Science, Inc. LOR Economic Greater New $4,000.00 Development = England Minority Corporate Supplier Sponsorship Development Renewal LOR 2018 V-BID Regents of the $50,000.00 Summit: V-BID at University of the Big House Michigan LOR AUTM 2018 Annual Association of $5,000.00 Meeting University Technology Mana LOR 2018 Annual BIONJ Inc. $10,000.00 Dinner Meeting LOR SOT Annual Society of $2,500.00 meeting Toxicology LOR Forum Group on George Washington $70,000.00 Arbovirus University Infections LOR World Vitiligo The Umass $2,500.00 Day 2018 Memorial Conference Foundation Inc. LOR Men's Health Men's Health $30,000.00 Month Network Sponsorship LOR OSU Pharmacy Oregon State $7,500.00 Partners Program University Foundation LOR 2018 Global International $5,000.00 Doctoral Biomedical Partnerships Research Annual Workshop Alliance LOR 2018 AAAS Annual American $25,000.00 Meeting Association for Sponsorship the Advancement LOR Cold Spring Cold Spring $15,000.00 Harbor Meetings Harbor and Courses Laboratory Program LOR 2018 Annual Event New York & New $10,000.00 Sponsorship Jersey Minority Supplier Development LOR 2018 Greater New American Diabetes $10,000.00 York Tour de Association Cure & Wellness Expo LOR National Minority Make Well Known $25,000.00 Cardiovascular Foundation Alliance LOR OASC Annual Ohio Association $1,000.00 Conference of Senior Centers LOR 2018 Flu Podcast Women In $5,000.00 Campaign Government Foundation, Inc. LOR 25th Annual Florida Health $5,000.00 National Care Coalition Conference LOR State Lung Health Respiratory $500.00 Education Health Program Association LOR CWAG 2018 Annual Conference of $5,000.00 Meeting Western Attorneys General LOR 2018 Town Hall American Society $203,900.00 Meeting Support for Preventive Cardiology LOR Get in Rhythm American $25,000.00 Stay in Rhythm-- Foundation for Afib Patient Women's Health Conference LOR PRISMS 10th Smith- PRISMS, Inc. $2,500.00 Magenis Syndrome Conference LOR Guidelines for Florida $50,000.00 Antimicrobial International Stewardship University Foundation LOR Latin American Florida $70,000.00 and Caribbean International Diabetes University Network: A Foundation framework LOR Assesment of Florida $60,000.00 acellular International vaccination University programs in Foundation Mexico, Costa LOR Bioorganic Gordon Research $1,000.00 Research Conferences Conference LOR National Trustees of $150,000.00 Community Health Boston Workers Project University LOR Health Innovation Springboard 2000 $25,000.00 Hub 2018 Enterprises, Inc. 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Microsatellites and Human Disease LOR 21st Annual HealthCare 21 $3,000.00 Health & Business Productivity Coalition Forum LOR 2018 Celebrating Blood and Marrow $25,000.00 a Second Chance Transplant at Life Information Survivorship Sympos LOR Patient Education Taking Control of $40,000.00 Diabetes Your Diabetes Conferences and Health Fairs LOR Patient Education Taking Control of $60,000.00 Diabetes Your Diabetes Conferences and Health Fairs LOR 2018 FH Global The FH Foundation $75,000.00 Summit LOR Chemical Biology Northeastern $1,000.00 in the Hub Section of the Symposium American Chemical Society LOR 2018 Champion of National Kidney $1,000.00 Hope Tribute Foundation of Dinner Michigan LOR 7th International CASSS $2,500.00 Symposium on Higher Order Structure of Protein Therapeutics LOR Bioassays 2018: CASSS $2,500.00 Scientific Approaches & Regulatory Strategies LOR A Taste of Ginger Joslin Diabetes $10,000.00 Gala Center, Inc. LOR 2018 Annual Western $10,000.00 Meeting Governors' Sponsorship Foundation LOR Community Hope Community Hope, $10,000.00 Annual Dinner Inc. LOR 8th International Florida $150,000.00 Conference on International Global Health University Foundation LOR 8th International Florida $14,000.00 Conference on International Global Health University Foundation LOR 2018 Machestic Machestic Dragons $5,500.00 Dragons ``Paddle for Pink'' Community Dragon LOR ``Visions of Diabetes $2,500.00 Hope'' Awards Foundation Inc. Dinner LOR Stick It to Mercy Health $2,000.00 Diabetes Foundation Joplin LOR 2018 FSH Society $2,000.00 International Research Conference LOR Teratology Teratology $1,500.00 Society 58th Society Annual Meeting LOR 255th ACS ACS Division of $5,000.00 National Meeting Biochemical and Exposition Technology (BIOT Division) LOR Forum on National Academy $50,000.00 Neuroscience and of Sciences Nervous System Disorders LOR 2018 National ACS Division of $3,000.00 Medicinal Medicinal Chemistry Chemistry Symposium LOR Giving Diabetes The Diabetes $2,500.00 the Blues Coalition of Conference Mississippi LOR Diabetes Care and Academy of $10,000.00 Dietetic Nutrition and Education Dietetics Program LOR 2018 Heart & The American $25,000.00 Stroke Ball Heart Association LOR RNA Therapeutics: The Umass $10,000.00 From Base Pairs Memorial to Bedsides Foundation Inc. LOR 2nd Annual Heart Metabolic $100,000.00 in Diabetes--HiD Endocrine Education Foundation LOR Immuno-Therapy The University of $50,000.00 Scientific Texas Foundation Workshop LOR Cell Culture Engineering $2,500.00 Engineering XVI Conferences Conference International LOR 2018 LVBCH Annual Lehigh Valley $1,000.00 Conference Business Coalition on Healthcare LOR Bowhay Institute The Council of $5,000.00 State Government, Ltd. LOR 2018 Lysosomes Gordon Research $2,000.00 and Endocytosis Conferences Gordon Research Conference LOR South Sound JDRF JDRF $1,000.00 One Walk International--N orthwest Chapter LOR 36th Annual JDRF $2,500.00 Nordstrom Beat the Bridge LOR Diabetes Under American Diabetes $1,000.00 the Dome Event Association LOR 2018 Wenger WomenHeart: The $25,000.00 Awards Dinner National Coalition for Women With Heart Disease LOR CRI's Cancer Research $25,000.00 Immunotherapy Institute Inc. Patient Summit Series LOR 2018 HBA Woman of Healthcare $15,000.00 the Year Event Businesswomen's Association LOR Transforming Dress for Success $15,000.00 Lives 20th year Northern New Celebration Jersey--10 LOR Recovery of American Chemical $10,000.00 Biological Society, Products XVIII Division of Conference Biochemistry LOR Friends for Life Children with $25,000.00 Orlando 2018 Diabetes Patient Conference LOR 2018 Orlando Children with $10,000.00 Fellows Program Diabetes LOR Hypoglycemia Endocrine Society $150,000.00 Quality Improvement/ Prevention Project LOR 2018 Annual Henry The Henry Kunkel $2,000.00 Kunkel Society Society c/o The Meeting Rockefeller LOR GPEN 2018 Globalization of $1,500.00 Scientific Pharmaceutics Meeting Education LOR 2018 Conference Employers Health $7,500.00 Sponsorship Coalition, Inc. LOR RVCC's 50th Raritan Valley $25,000.00 Anniversary Community Golden Harvest College Foundat Gala LOR 2018 PQA Annual Healthcare $6,100.00 Meeting Businesswomen's Association LOR 2018 PQA Annual PQA, Inc. $12,500.00 Meeting LOR eValue8 Project Northeast $2,500.00 Business Group on Health LOR Annual Good Grief Good Grief Inc. $3,500.00 Gala LOR 8th Annual Center for $10,000.00 Diversity, Healthcare Inclusion, & Innovation Health Equity Symposium LOR Real World American Diabetes $210,000.00 Evidence Association Generation and Analysis Research Symposium LOR From Rare to Keystone Symposia $3,000.00 Care: Discovery, on Molecular and Modeling and Cellular Translation of Rare Diseases LOR 6th Annual International $15,000.00 Meeting of the Cytokine and International Interferon Cytokine & Society Interferon LOR Diabetes and CV Icahn School of $30,000.00 Risk Factors Medicine at Program Mount Sinai LOR Prix Galien USA The Galien $15,000.00 Forum Foundation LOR Learning Sessions The Health $5,000.00 Program Collaborative LOR Horton's Kids Horton's Kids, $15,000.00 Comprehensive Inc. Programming for At-Risk Children LOR Children's Health Children's Health $30,000.00 Fund 2018 Annual Fund Benefit LOR 60th Anniversary Project Hope The $10,000.00 Project HOPE People To People Gala Health LOR Structural Harvard Medical $2,500.00 Biology Meeting School LOR PROMIS: Global Harvard Medical $2,500.00 Advances in School Methodology and Clinical Science LOR 68th Annual Somerset County $2,500.00 Outstanding Business Citizen of the Partnership Year Awards Dinner LOR Annual Meeting Somerset County $2,500.00 Awards Luncheon Business 2018 Partnership LOR Illinois Diabetes Illinois Diabetes $250.00 Caucus Caucus Fundraiser Foundation LOR 18th annual The Virginia $700.00 luncheon Public Access Project LOR Grand Tastings Jersey Battered $15,000.00 XXIV Women's Service, Inc. LOR d18 Executive The diaTribe $250,000.00 Innovation Lab Foundation on Diabetes and Prediabetes LOR 2018 Scientific Children's $10,000.00 Program in Hospital Cellular and Corporation Molecular Medicine LOR JDRF One Walk, JDRF $2,500.00 Washington, DC LOR WOCIP 2018-2019 Women of Color in $20,000.00 Annual Meeting Pharma LOR WOCIP 2018-2019 Women of Color in $20,000.00 Annual Meeting Pharma LOR Koch Institute Massachusetts $5,000.00 2018 Summer Institute of Symposium Technology LOR Koch Institute Massachusetts $5,000.00 2018 Summer Institute of Symposium Technology LOR Event Sponsorship- Discovering $10,000.00 Discovering Justice Justice 20th Anniversary Gala LOR Boston Children's $3,000.00 Postdoctoral Hospital Association Corporation Symposium on Careers and Collaboration in Science LOR ONE: The Ultimate Taking Control of $20,000.00 Conference for Your Diabetes Adult Type 1 LOR 2018 Gordon Gordon Research $3,000.00 Research Conferences Conference on Heterocycles LOR PDAF Fundraiser Prescription Drug $1,250.00 Sponsorship Assistance Foundation LOR Generations Gala Adult Day Center $3,000.00 Event of Somerset County LOR 12th Annual The diaTribe $10,000.00 Diabetes Forum Foundation LOR 2018 Triangle JDRF $10,000.00 Hope Glala LOR Lecture Series The New York $25,000.00 Program Academy of Sciences LOR Division of ACS Division of $3,000.00 Medicinal Medicinal Chemistry Chemistry Program ACS National Meeting LOR 11th Annual Brigham and $2,000.00 Polycystic Women's Hospital Kidney Disease Symposium LOR DA4S East Coast Diversity $7,500.00 2018 Alliance for Science, Inc. LOR The Jessica Dana Farber $5,000.00 Ingram Lecture Cancer Institute Series LOR The Jessica Dana Farber $5,000.00 Ingram Lecture Cancer Institute Series LOR Key Initiatives Prostate Cancer $30,000.00 Program Education Council LOR NEQCA Annual New England $5,000.00 Forum Quality Care Alliance LOR MMRF 2018 Myeloma Multiple Myeloma $100,000.00 Patient and Research Caregiver Foundation Education Program LOR National Forum National Forum $200,000.00 for Heart for Heart Disease Disease and Stroke LOR TB Survivors for National TB $5,000.00 Patient Controllers Education Association LOR 9th Annual Spirit Association of $50,000.00 of the Heart Black Awards Dinner Cardiologists LOR Change for Women Catalyst Inc. $15,000.00 in the Workplace Program LOR 2018 Annual Washington Policy $3,500.00 Dinner Center LOR National The Mended $25,000.00 Education & Hearts, Inc. Training Conference 2018 LOR 2018 ICSA International $3,000.00 Symposium Chinese Statistical Association LOR BMT InfoNet Blood and Marrow $10,000.00 Patient Guide Transplant Reprint Information LOR Research on Harvard T.H. Chan $200,000.00 Health School of Public Technology Health Assessment LOR DIA Inspires Drug Information $4,500.00 Award Dinner Asssociation (DIA) LOR Diabetes Fundacion Centro $7,000.00 Education Pediatrico de Program for Diabetes School Personnel and T1D Students LOR NCCN Guidelines NCCN Foundation $25,000.00 for Patients guide LOR Fall Meeting Middle Atlantic $1,000.00 Sponsorship Reproduction and Teratolog LOR PROMIS: Global PROMIS Health $15,000.00 Advances in Organization Methodology and (PHO) Clinical Science LOR Immunization Idaho $2,500.00 Summit 2018 Immunization Coalition LOR Bob Langer 70th Rutgers $20,000.00 Birthday Gala University and Symposium Foundation LOR TMA Group Annual Texas Medical $1,200.00 Meeting Association LOR Clinical Inertia American Diabetes $300,000.00 Campaign Association LOR Life Sciences Life Sciences PA $250.00 Event June 2018 LOR CE in the CASSS $2,500.00 Biotechnology & Pharmaceutical Industries: 20th Symposium LOR 15th Symposium on CASSS $2,500.00 the Practical Applications of Mass Spectrometry LOR NCQA's Quality National $10,000.00 Talks 2018 Committee for Quality Assurance LOR Gala of Giving Operation Jersey $3,000.00 Country Style Cares 2018 LOR Cell & Gene CASSS $5,000.00 Therapy Products (CGTP): Manufacturing, Quality LOR Newletter Funding Skin Cancer $100,000.00 Foundation LOR Advocating for Lupus Foundation $5,000.00 Chronic Disease of America Inc. Patients LOR Inspiring Hope Cancer Support $2,500.00 Gala Community Central LOR 2018 National Lung Cancer $10,000.00 Advocacy Summit Alliance LOR Bastille Day Resources USA $5,000.00 Boston 2018 Inc. LOR Bastille Day Resources USA $10,000.00 Washington DC Inc. 2018 LOR The Lancet Women Icahn School of $100,000.00 and Medicine at Cardiovascular Mount Sinai Disease Commission LOR Northeast CASSS $2,500.00 Regional Forum October 2018 LOR 2018 National Research!America $25,000.00 Health Research Forum LOR Promoting Nurses Preventive $25,000.00 as Leaders in Cardiovascular Prevention Nurses Program Association LOR ACCC educational Association of $144,000.00 program funding Community Cancer Centers LOR Patient Access Alliance for $75,000.00 Collaborative Patient Access LOR NJMLA 2018 Annual New Jersey Muslim $1,250.00 Eid Gala Lawyer Association LOR 2018 Biomarkers Foundation for $2,500.00 Consortium the National meeting Institutes of Health LOR Pro Bono Pro Bono $25,000.00 Partnership 2018 Partnership Gala LOR Tour de Cure American Diabetes $2,500.00 Hawaii Association LOR 19th Annual Patient Advocate $10,000.00 Patient Congress Foundation LOR Patient Education ZERO--The End of $8,000.00 Webinar Funding Prostate Cancer LOR 2018 Diabetes Joslin Diabetes $5,000.00 Coalition Center, Inc. Conference LOR Mary's Center Mary's Center $30,000.00 2018 Symposium LOR 2018 Safety Safety $2,500.00 Pharmacology Pharmacology Society Annual Society meeting LOR Drugs for Drugs for $50,000.00 Neglected Neglected Diseases Diseases initiative Initiative, (DNDi)'s Making North American Medical History Inc. LOR Drugs for Drugs for $25,000.00 Neglected Neglected Diseases Diseases initiative Initiative North (DNDi)'s Making American Inc. Medical History LOR Drugs for Drugs for $25,000.00 Neglected Neglected Diseases Diseases initiative Initiative North (DNDi)'s Making American Inc. Medical History LOR Pharmacy Alumni The Ohio State $1,000.00 Society University Pharmathon 5k Foundation Sponsorship LOR Diabetes Policy Alliance for $150,000.00 Advocacy Patient Access Initiatives LOR Yale Yale University $2,000.00 Immunobiology Student Symposium 2018 LOR ConnecT1D Family ConnecT1D $5,000.00 Camp 2018 LOR 2018 Alumni Hall Hispanic $25,000.00 of Fame Gala Scholarship Fund Dinner LOR JDRF One Walk JDRF $5,000.00 LOR ACS CAN National American Cancer $35,000.00 Advocacy Society Cancer Activities Action Network LOR American College American College $2,500.00 of Toxicology of Toxicology 39th Annual Meeting LOR Fall Advocacy Day ASTS Foundation $15,000.00 LOR 2018 OFII Annual Organization for $15,000.00 Dinner International Investment LOR 2018 Patient & Biotechnology $10,000.00 Health Advocacy Innovation Summit Organization LOR 2018 Indiana Tour American Diabetes $2,500.00 de Cure Association, Indiana LOR 2018 JDRF One JDRF $5,000.00 Walk Syracuse International LOR 12th Annual Gala International $10,000.00 Celebration Myeloma Foundation LOR 14th Annual National Alliance $2,500.00 Meeting of of State NASPCC Prostate Cancer LOR Translational American $25,000.00 Cancer Research Association for for Basic Cancer Research Scientists Workshop LOR Boston Heart Walk American Heart $5,000.00 Association LOR JDRF One Walk JDRF $5,000.00 2018 International LOR Airline Benefit Americares $12,000.00 Gala LOR Improving National Minority $125,000.00 Diabetes and Quality Forum Cardiovasular Disease Management LOR Digital Health MassChallenge, $100,000.00 Accellerator Inc. Program LOR Multiple Myeloma Blood and Marrow $3,750.00 Patient Survival Transplant Guide Information LOR 2018 ACS CAN American Cancer $25,000.00 State Events Society Cancer Program Action Network LOR Healthcare American College $1,000.00 Leaders of Healthcare Educational Executives Events LOR 36th Annual President and $10,000.00 Retreat for the Fellows of Harvard/MIT MD- Harvard College PhD Program LOR Moving the Needle Healthcare $1,000.00 on Gender Parity Businesswomen's Association LOR Employer's Guide Northeast $17,500.00 to Digital Business Group Diabetes on Health Prevention and Management LOR 10th Annual Prevent Cancer $5,000.00 Health Fair and Foundation 5k Walk/Run LOR 16th Annual Gala Fundacion Centro $3,500.00 Dinner Pediatrico de Diabetes LOR Advancement and Cross-Company $2,500.00 Challenges Abuse Liability Meeting Council LOR Respiraory Alliance for $50,000.00 Therapy Access Patient Access Working Group LOR The Champions For Skin Cancer $25,000.00 Change Gala Foundation LOR High Hopes Gala Joslin Diabetes $25,000.00 Center, Inc. LOR Friends Annual Friends of Cancer $10,000.00 Cancer Research Research Leadership Awards LOR Women Building Virginia Bio $3,000.00 Bio Sponsorship LOR NACHW Trustees of $20,000.00 Organizational Boston Launch University Announcement Event LOR 2018 PQA PQA, Inc. $7,500.00 Leadership Summit LOR High Level Speak Up Africa d/ $25,000.00 Conference and b/a The Access Awards Event Challenge LOR International International $90,000.00 Myeloma Myeloma Foundation Foundation Patient Initiative Programs LOR NCCN Innovation National $40,000.00 Pilot Program Comprehensive Cancer Network LOR Annual AMCP Academy of $18,000.00 meeting Managed Care Pharmacy LOR Solvable Problems The diaTribe $48,000.00 in Diabetes Foundation Program LOR NESOT Annual Society of $1,500.00 Meeting Toxicology LOR Patient Advocacy Cancer Support $75,000.00 Kit for Multiple Community Myeloma LOR Patient Education National Kidney $7,500.00 Brochure Big Ask Foundation, Inc. Big Give LOR Patient Awareness National Hispanic $25,000.00 and Education Medical Program for Association Hispanic Patient LOR Diabetes Family Fundacion Centro $5,000.00 Day Sponsorship Pediatrico de Diabetes LOR Annual Promise JDRF $20,000.00 Ball International LOR Congress American Society $10,000.00 Sponsorship of Hematology LOR Scientific Annual Lupus Research $10,000.00 Conference Alliance LOR R3 Annual Forum Multi Regional $7,500.00 Clinical Trial Center of Brigham LOR Diabetes Public Health $10,000.00 Prevention on Advocates the Ground in California Sponsorship LOR Northcrest Annual NorthCrest $2,500.00 Gala Medical Center Foundation LOR 19th Annual GLBTQ Legal $3,000.00 Spirit of Advocates & Justice Award Defenders (GLAD) Dinner LOR AUTM Annual Association of $5,000.00 Meeting University Technology Mana LOR TCYOD Patient Taking Control of $75,000.00 Conferences and Your Diabetes Health Fairs LOR New Jersey Smart RideWise, Inc. $1,000.00 Workplace Annual recognition event LOR Breakfast Women In $7,500.00 Sponsorship Government Foundation, Inc. LOR Patient Education Malecare $20,000.00 African American Men with Prostate Cancer LOR Patient Education Malecare $15,000.00 Brochure: Simple Cancer LOR ONE: The Taking Control of $75,000.00 Ultimaite Your Diabetes Conference and Retreate for Adults with Type I LOR Women in All in Together $40,000.00 Healthcare Campaign Inc. Policy Forum LOR Innovation Labs The diaTribe $100,000.00 on Diabetes and Foundation Prediabetes LOR Annual Joe Joe Andruzzi $5,000.00 Andruzzi Foundation Inc. Foundation Gala LOR Corporate AMGA $25,000.00 Sponsorship for Institute for Quality Leadership LOR Patient Awareness ZERO--The End of $10,000.00 and Education Prostate Cancer Program LOR Congress Metabolic $50,000.00 Sponsorship Endocrine Education Foundation LOR 2018 Annual PCMA $95,000.00 Meeting Sponsorship LOR PCMA Business PCMA $80,000.00 Forum Sponsorship LOR Cardiovascular Association of $30,000.00 Risk Reduction Black Project Cardiologists LOR Corporate California Life $8,500.00 Sponsorship for Sciences Institute for Association Life Sciences Academy LOR Friends Friends of Cancer $50,000.00 ImmunoOncology Research Programs LOR Patient Education Prostate Cancer $20,000.00 Brochure: Education Chemotherary in Council Prosate Cancer LOR 2018 Patient BIONJ Inc. $1,000.00 Advocacy Summit Sponsorship LOR Patient Guide Arizona Myeloma $10,000.00 Living with Network (AZMN) Myeloma LOR Yellow Fever Fondation Merieux $10,000.00 Symposium USA, Inc. LOR Patient Education Blood and Marrow $40,000.00 Brochure on Transplant Transplantation Information LOR MBGH Sponsorship Midwest Business $20,000.00 Request Group on Health LOR Patient Education American Academy $30,000.00 Brochure on SCC of Dermatology Inc. LOR HBA Woman of the Healthcare $22,250.00 Year Luncheon Businesswomen's Association LOR Corporate Midwest Business $30,000.00 Sponsorship Group on Health ------------------------------------------------------------------------ Date of Primary Primary Physician/Teaching Payment Amount Purpose Nature Hospital Name (NPI) ------------------------------------------------------------------------ 11/10/2015 $75,000.00 Fellowship Cash or Cash Vanderbilt Equivalent University Hospital ------------------------------------------------------------------------ 06/15/2015 $74,987.00 Fellowship Cash or Cash Childrens Hospital Equivalent Medical Center ------------------------------------------------------------------------ 02/24/2015 $75,000.00 Fellowship Cash or Cash Langley Porter Equivalent Psychiatric Hospital ------------------------------------------------------------------------ 08/01/2015 $75,000.00 Fellowship Cash or Cash Emory University Equivalent Hospital ------------------------------------------------------------------------ 07/01/2015 $75,000.00 Fellowship Cash or Cash Uci Medical Center Equivalent (.) ------------------------------------------------------------------------ 05/26/2015 $75,000.00 Fellowship Cash or Cash Uci Medical Center Equivalent (.) ------------------------------------------------------------------------ 04/07/2015 $43,494.57 Fellowship Cash or Cash University of Equivalent Alabama Hospital ------------------------------------------------------------------------ 05/17/2016 $75,000.00 Fellowship Cash or Cash Vanderbilt Equivalent University Hospitals & Cl (.) ------------------------------------------------------------------------ 06/21/2016 $75,000.00 Fellowship Cash or Cash Emory University Equivalent Hospital (.) ------------------------------------------------------------------------ 03/09/2016 $77,537.90 Fellowship Cash or Cash Emory University Equivalent Hospital (.) ------------------------------------------------------------------------ 06/07/2016 $77,317.00 Fellowship Cash or Cash Ann & Robert H. Equivalent Lurie Childrens Hos (.) ------------------------------------------------------------------------ 03/01/2016 $63,000.00 Fellowship Cash or Cash Resnick Equivalent Neuropsychiatric Hospital At (.) ------------------------------------------------------------------------ 06/07/2016 $75,000.00 Fellowship Cash or Cash University Of Equivalent Alabama Hospital (.) ------------------------------------------------------------------------ 06/27/2017 $75,000.00 Fellowship Cash or Cash Ann & Robert H. Equivalent Lurie Childrens Hos (1497018154) ------------------------------------------------------------------------ 03/02/2017 $75,000.00 Fellowship Cash or Cash Hospital Of The Equivalent Univ Of Penna (1003946153) ------------------------------------------------------------------------ 07/01/2017 $75,000.00 Fellowship Cash or Cash Cooper University Equivalent Hospital (1053654749) ------------------------------------------------------------------------ 07/01/2017 $75,000.00 Fellowship Cash or Cash Childrens Hospital Equivalent Medical Center (1083665137) ------------------------------------------------------------------------ 07/01/2017 $75,000.00 Fellowship Cash or Cash Uci Medical Center Equivalent (.) ------------------------------------------------------------------------ 07/01/2017 $63,000.00 Fellowship Cash or Cash Resnick Equivalent Neuropsychiatric Hospital At (1124327853) ------------------------------------------------------------------------ 12/12/2017 $75,000.00 Fellowship Cash or Cash Emory University Equivalent Hospital (.) ------------------------------------------------------------------------ 12/12/2017 $63,000.00 Fellowship Cash or Cash Resnick Equivalent Neuropsychiatric Hospital At (1124327853) ------------------------------------------------------------------------ 12/17/2017 $75,000.00 Fellowship Cash or Cash Uci Medical Center Equivalent (.) ------------------------------------------------------------------------ 12/06/2017 $75,000.00 Fellowship Cash or Cash Vanderbilt Equivalent University Medical Center (1104202761) ------------------------------------------------------------------------ 03/02/2017 $75,000.00 Fellowship Cash or Cash Emory University Equivalent Hospital (.) ------------------------------------------------------------------------ 03/14/2017 $73,714.12 Fellowship Cash or Cash University Of Equivalent Alabama Hospital (.) ------------------------------------------------------------------------ ------------------------------------------------------------------------ Payment Report Recipient Type Address Line 1 City State ZIP ------------------------------------------------------------------------ Teaching hospital 1211 MEDICAL NASHVILLE TN 37232 CENTER DRIVE ------------------------------------------------------------------------ Teaching hospital 3333 BURNET CINCINNATI OH 45229 AVENUE MLC #4900 ------------------------------------------------------------------------ Teaching hospital 405 PARNASUS SAN CA 94143 FRANCISCO ------------------------------------------------------------------------ Teaching hospital 1364 CLIFTON ATLANTA GA 30302 ROAD ------------------------------------------------------------------------ Teaching hospital 101 CITY DRIVE ORANGE CA 92868 SOUTH ------------------------------------------------------------------------ Teaching hospital 101 CITY DRIVE ORANGE CA 92868 SOUTH ------------------------------------------------------------------------ Teaching hospital 619 SOUTH 19TH BIRMINGHAM AL 35233 STREET ------------------------------------------------------------------------ Teaching hospital 1211 MEDICAL NASHVILLE TN 37232 CENTER DRIVE ------------------------------------------------------------------------ Teaching hospital 1364 CLIFTON ATLANTA GA 30302 ROAD ------------------------------------------------------------------------ Teaching hospital 1364 CLIFTON ATLANTA GA 30302 ROAD ------------------------------------------------------------------------ Teaching hospital 225 EAST CHICAGO CHICAGO IL 60611 AVENUE ------------------------------------------------------------------------ Teaching hospital 150 UCLA MEDICAL LOS ANGELES CA 90095 PLAZA ------------------------------------------------------------------------ Teaching hospital 619 SOUTH 19TH BIRMINGHAM AL 35233 STREET ------------------------------------------------------------------------ Teaching hospital 225 EAST CHICAGO CHICAGO IL 60611 AVENUE ------------------------------------------------------------------------ Teaching hospital 3400 SPRUCE PHILADELPHIA PA 19104 STREET ------------------------------------------------------------------------ Teaching hospital ONE COOPER PLAZA CAMDEN NJ 08103 ------------------------------------------------------------------------ Teaching hospital 3333 BURNET CINCINNATI OH 45229 AVENUE MLC #4900 ------------------------------------------------------------------------ Teaching hospital 101 CITY DRIVE ORANGE CA 92868 SOUTH ------------------------------------------------------------------------ Teaching hospital 150 UCLA MEDICAL LOS ANGELES CA 90095 PLAZA ------------------------------------------------------------------------ Teaching hospital 1364 CLIFTON ATLANTA GA 30302 ROAD ------------------------------------------------------------------------ Teaching hospital 150 UCLA MEDICAL LOS ANGELES CA 90095 PLAZA ------------------------------------------------------------------------ Teaching hospital 101 CITY DRIVE ORANGE CA 92868 SOUTH ------------------------------------------------------------------------ Teaching hospital 1211 MEDICAL NASHVILLE TN 37232 CENTER DRIVE ------------------------------------------------------------------------ Teaching hospital 1364 CLIFTON ATLANTA GA 30302 ROAD ------------------------------------------------------------------------ Teaching hospital 619 SOUTH 19TH BIRMINGHAM AL 35233 STREET ------------------------------------------------------------------------ ------------------------------------------------------------------------ Date of Payment Amount Primary Purpose Primary Nature ------------------------------------------------------------------------ 08/11/2015 $124,572.50 Investigator Cash or Cash Sponsored Trial Equivalent ------------------------------------------------------------------------ 12/15/2015 $74,327.00 Investigator Cash or Cash Sponsored Trial Equivalent ------------------------------------------------------------------------ 10/20/2015 $174,088.90 Investigator Cash or Cash Sponsored Trial Equivalent ------------------------------------------------------------------------ 09/08/2015 $5,648.00 Investigator Cash or Cash Sponsored Trial Equivalent ------------------------------------------------------------------------ 09/08/2015 $7,060.00 Investigator Cash or Cash Sponsored Trial Equivalent ------------------------------------------------------------------------ 09/08/2015 $7,060.00 Investigator Cash or Cash Sponsored Trial Equivalent ------------------------------------------------------------------------ 09/08/2015 $5,648.00 Investigator Cash or Cash Sponsored Trial Equivalent ------------------------------------------------------------------------ 09/08/2015 $4,236.00 Investigator Cash or Cash Sponsored Trial Equivalent ------------------------------------------------------------------------ 09/08/2015 $350.00 Investigator Cash or Cash Sponsored Trial Equivalent ------------------------------------------------------------------------ 09/08/2015 $1,250.00 Investigator Cash or Cash Sponsored Trial Equivalent ------------------------------------------------------------------------ 09/08/2015 $1,086.00 Investigator Cash or Cash Sponsored Trial Equivalent ------------------------------------------------------------------------ 03/24/2015 $5,648.00 Investigator Cash or Cash Sponsored Trial Equivalent ------------------------------------------------------------------------ 03/24/2015 $2,824.00 Investigator Cash or Cash Sponsored Trial Equivalent ------------------------------------------------------------------------ 03/24/2015 $2,824.00 Investigator Cash or Cash Sponsored Trial Equivalent ------------------------------------------------------------------------ 03/24/2015 $9,775.00 Investigator Cash or Cash Sponsored Trial Equivalent ------------------------------------------------------------------------ 03/24/2015 $750.00 Investigator Cash or Cash Sponsored Trial Equivalent ------------------------------------------------------------------------ 10/27/2015 $7,234.45 Investigator Cash or Cash Sponsored Trial Equivalent ------------------------------------------------------------------------ 12/08/2015 $11,074.80 Investigator Cash or Cash Sponsored Trial Equivalent ------------------------------------------------------------------------ 09/08/2015 $6,698.00 Investigator Cash or Cash Sponsored Trial Equivalent ------------------------------------------------------------------------ 09/08/2015 $1,551.00 Investigator Cash or Cash Sponsored Trial Equivalent ------------------------------------------------------------------------ 01/06/2015 $127,160.70 Investigator Cash or Cash Sponsored Trial Equivalent ------------------------------------------------------------------------ 01/06/2015 $385,403.00 Investigator Cash or Cash Sponsored Trial Equivalent ------------------------------------------------------------------------ 10/27/2015 $137,506.80 Investigator Cash or Cash Sponsored Trial Equivalent ------------------------------------------------------------------------ 02/24/2015 $35,672.06 Investigator Cash or Cash Sponsored Trial Equivalent ------------------------------------------------------------------------ 03/17/2015 $36,130.95 Investigator Cash or Cash Sponsored Trial Equivalent ------------------------------------------------------------------------ 09/15/2015 $7,226.19 Investigator Cash or Cash Sponsored Trial Equivalent ------------------------------------------------------------------------ 02/10/2015 $325,000.00 Investigator Cash or Cash Sponsored Trial Equivalent ------------------------------------------------------------------------ 10/20/2015 $5,000.00 Investigator Cash or Cash Sponsored Trial Equivalent ------------------------------------------------------------------------ 07/21/2015 $5,000.00 Investigator Cash or Cash Sponsored Trial Equivalent ------------------------------------------------------------------------ 07/07/2015 $49,000.00 Investigator Cash or Cash Sponsored Trial Equivalent ------------------------------------------------------------------------ 07/21/2015 $16,089.68 Investigator Cash or Cash Sponsored Trial Equivalent ------------------------------------------------------------------------ 06/02/2015 $14,000.00 Investigator Cash or Cash Sponsored Trial Equivalent ------------------------------------------------------------------------ 02/10/2015 $5,000.00 Investigator Cash or Cash Sponsored Trial Equivalent ------------------------------------------------------------------------ 01/06/2015 $20,100.00 Investigator Cash or Cash Sponsored Trial Equivalent ------------------------------------------------------------------------ 03/24/2015 $1,412.00 Investigator Cash or Cash Sponsored Trial Equivalent ------------------------------------------------------------------------ 03/24/2015 $1,412.00 Investigator Cash or Cash Sponsored Trial Equivalent ------------------------------------------------------------------------ 03/24/2015 $1,412.00 Investigator Cash or Cash Sponsored Trial Equivalent ------------------------------------------------------------------------ 04/14/2015 $8,363.00 Investigator Cash or Cash Sponsored Trial Equivalent ------------------------------------------------------------------------ 09/08/2015 $7,760.00 Investigator Cash or Cash Sponsored Trial Equivalent ------------------------------------------------------------------------ 03/03/2015 $4,000.00 Investigator Cash or Cash Sponsored Trial Equivalent ------------------------------------------------------------------------ 10/27/2015 $28,585.85 Investigator Cash or Cash Sponsored Trial Equivalent ------------------------------------------------------------------------ 04/14/2015 $85,757.55 Investigator Cash or Cash Sponsored Trial Equivalent ------------------------------------------------------------------------ 10/20/2015 $28,585.85 Investigator Cash or Cash Sponsored Trial Equivalent ------------------------------------------------------------------------ 03/03/2015 $61,725.52 Investigator Cash or Cash Sponsored Trial Equivalent ------------------------------------------------------------------------ 03/03/2015 $11,176.62 Investigator Cash or Cash Sponsored Trial Equivalent ------------------------------------------------------------------------ 03/03/2015 $24,246.00 Investigator Cash or Cash Sponsored Trial Equivalent ------------------------------------------------------------------------ 10/13/2015 $125,000.00 Investigator Cash or Cash Sponsored Trial Equivalent ------------------------------------------------------------------------ 12/15/2015 $200,000.00 Investigator Fees Sponsored Trial ------------------------------------------------------------------------ 01/13/2015 $39,771.64 Investigator Cash or Cash Sponsored Trial Equivalent ------------------------------------------------------------------------ 05/05/2015 $39,771.64 Investigator Cash or Cash Sponsored Trial Equivalent ------------------------------------------------------------------------ 06/09/2015 $39,771.65 Investigator Cash or Cash Sponsored Trial Equivalent ------------------------------------------------------------------------ 05/19/2015 $119,166.66 Investigator Cash or Cash Sponsored Trial Equivalent ------------------------------------------------------------------------ 05/26/2015 $185,900.01 Investigator Cash or Cash Sponsored Trial Equivalent ------------------------------------------------------------------------ 06/02/2015 $61,966.67 Investigator Cash or Cash Sponsored Trial Equivalent ------------------------------------------------------------------------ 07/28/2015 $61,966.66 Investigator Cash or Cash Sponsored Trial Equivalent ------------------------------------------------------------------------ 03/17/2015 $126,059.09 Investigator Cash or Cash Sponsored Trial Equivalent ------------------------------------------------------------------------ 03/17/2015 $126,059.09 Investigator Cash or Cash Sponsored Trial Equivalent ------------------------------------------------------------------------ 04/07/2015 $174,088.90 Investigator Cash or Cash Sponsored Trial Equivalent ------------------------------------------------------------------------ 01/06/2015 $59,187.50 Investigator Cash or Cash Sponsored Trial Equivalent ------------------------------------------------------------------------ 05/19/2015 $59,187.50 Investigator Cash or Cash Sponsored Trial Equivalent ------------------------------------------------------------------------ 04/14/2015 $11,120.67 Investigator Cash or Cash Sponsored Trial Equivalent ------------------------------------------------------------------------ 05/26/2015 $28,612.00 Investigator Cash or Cash Sponsored Trial Equivalent ------------------------------------------------------------------------ 06/16/2015 $28,612.00 Investigator Cash or Cash Sponsored Trial Equivalent ------------------------------------------------------------------------ 08/11/2015 $7,234.45 Investigator Cash or Cash Sponsored Trial Equivalent ------------------------------------------------------------------------ 03/24/2015 $28,830.75 Investigator Cash or Cash Sponsored Trial Equivalent ------------------------------------------------------------------------ 02/17/2015 $30,167.85 Investigator Cash or Cash Sponsored Trial Equivalent ------------------------------------------------------------------------ 03/17/2015 $24,228.75 Investigator Cash or Cash Sponsored Trial Equivalent ------------------------------------------------------------------------ 08/11/2015 $355,830.00 Investigator Cash or Cash Sponsored Trial Equivalent ------------------------------------------------------------------------ 05/26/2015 $28,777.00 Investigator Cash or Cash Sponsored Trial Equivalent ------------------------------------------------------------------------ 03/17/2015 $8,329.00 Investigator Cash or Cash Sponsored Trial Equivalent ------------------------------------------------------------------------ 04/14/2015 $9,229.00 Investigator Cash or Cash Sponsored Trial Equivalent ------------------------------------------------------------------------ 11/19/2015 $53,400.00 Investigator Product Sponsored Trial ------------------------------------------------------------------------ 12/10/2015 $214,706.70 Investigator Product Sponsored Trial ------------------------------------------------------------------------ 12/17/2015 $7,425.18 Investigator Product Sponsored Trial ------------------------------------------------------------------------ 11/23/2015 $12,375.30 Investigator Product Sponsored Trial ------------------------------------------------------------------------ 12/07/2015 $160,228.80 Investigator Product Sponsored Trial ------------------------------------------------------------------------ 11/23/2015 $14,850.36 Investigator Product Sponsored Trial ------------------------------------------------------------------------ 01/26/2016 $114,107.36 Investigator Cash or Cash Sponsored Trial Equivalent ------------------------------------------------------------------------ 01/12/2016 $250,000.00 Investigator Cash or Cash Sponsored Trial Equivalent ------------------------------------------------------------------------ 04/26/2016 $54,115.17 Investigator Cash or Cash Sponsored Trial Equivalent ------------------------------------------------------------------------ 05/17/2016 $174,088.90 Investigator Cash or Cash Sponsored Trial Equivalent ------------------------------------------------------------------------ 01/26/2016 $35,000.00 Investigator Cash or Cash Sponsored Trial Equivalent ------------------------------------------------------------------------ 06/02/2016 $18,334.48 Investigator Cash or Cash Sponsored Trial Equivalent ------------------------------------------------------------------------ 09/13/2016 $174,088.90 Investigator Cash or Cash Sponsored Trial Equivalent ------------------------------------------------------------------------ 06/28/2016 $224,593.02 Investigator Cash or Cash Sponsored Trial Equivalent ------------------------------------------------------------------------ 09/13/2016 $22,950.00 Investigator Cash or Cash Sponsored Trial Equivalent ------------------------------------------------------------------------ 02/09/2016 $50,279.75 Investigator Cash or Cash Sponsored Trial Equivalent ------------------------------------------------------------------------ 04/19/2016 $28,830.75 Investigator Cash or Cash Sponsored Trial Equivalent ------------------------------------------------------------------------ 01/12/2016 $24,228.75 Investigator Cash or Cash Sponsored Trial Equivalent ------------------------------------------------------------------------ 01/19/2016 $24,228.75 Investigator Cash or Cash Sponsored Trial Equivalent ------------------------------------------------------------------------ 04/26/2016 $33,332.00 Investigator Cash or Cash Sponsored Trial Equivalent ------------------------------------------------------------------------ 03/08/2016 $30,589.00 Investigator Cash or Cash Sponsored Trial Equivalent ------------------------------------------------------------------------ 07/19/2016 $7,234.45 Investigator Cash or Cash Sponsored Trial Equivalent ------------------------------------------------------------------------ 06/28/2016 $15,750.00 Investigator Cash or Cash Sponsored Trial Equivalent ------------------------------------------------------------------------ 09/27/2016 $42,502.00 Investigator Cash or Cash Sponsored Trial Equivalent ------------------------------------------------------------------------ 06/07/2016 $38,530.00 Investigator Product Sponsored Trial ------------------------------------------------------------------------ 06/15/2016 $22,106.80 Investigator Product Sponsored Trial ------------------------------------------------------------------------ 06/16/2016 $3,103.89 Investigator Product Sponsored Trial ------------------------------------------------------------------------ 06/22/2016 $114,600.84 Investigator Product Sponsored Trial ------------------------------------------------------------------------ 06/23/2016 $88,057.50 Investigator Product Sponsored Trial ------------------------------------------------------------------------ 06/27/2016 $12,930.00 Investigator Product Sponsored Trial ------------------------------------------------------------------------ 01/13/2016 $18,768.00 Investigator Product Sponsored Trial ------------------------------------------------------------------------ 01/14/2016 $88,057.50 Investigator Product Sponsored Trial ------------------------------------------------------------------------ 01/14/2016 $58,710.00 Investigator Product Sponsored Trial ------------------------------------------------------------------------ 01/14/2016 $959.62 Investigator Product Sponsored Trial ------------------------------------------------------------------------ 01/14/2016 $3,047.08 Investigator Product Sponsored Trial ------------------------------------------------------------------------ 01/14/2016 $1,556.04 Investigator Product Sponsored Trial ------------------------------------------------------------------------ 01/14/2016 $3,941.70 Investigator Product Sponsored Trial ------------------------------------------------------------------------ 01/14/2016 $661.42 Investigator Product Sponsored Trial ------------------------------------------------------------------------ 01/27/2016 $293,490.00 Investigator Product Sponsored Trial ------------------------------------------------------------------------ 02/09/2016 $12,505.30 Investigator Product Sponsored Trial ------------------------------------------------------------------------ 02/12/2016 $76,515.00 Investigator Product Sponsored Trial ------------------------------------------------------------------------ 02/16/2016 $36,067.85 Investigator Product Sponsored Trial ------------------------------------------------------------------------ 02/18/2016 $58,710.00 Investigator Product Sponsored Trial ------------------------------------------------------------------------ 03/29/2016 $12,930.00 Investigator Product Sponsored Trial ------------------------------------------------------------------------ 03/29/2016 $64,130.00 Investigator Product Sponsored Trial ------------------------------------------------------------------------ 03/29/2016 $25,730.00 Investigator Product Sponsored Trial ------------------------------------------------------------------------ 03/31/2016 $3,103.89 Investigator Product Sponsored Trial ------------------------------------------------------------------------ 04/04/2016 $76,930.00 Investigator Product Sponsored Trial ------------------------------------------------------------------------ 04/13/2016 $58,710.00 Investigator Product Sponsored Trial ------------------------------------------------------------------------ 04/19/2016 $152,796.13 Investigator Product Sponsored Trial ------------------------------------------------------------------------ 04/28/2016 $12,930.00 Investigator Product Sponsored Trial ------------------------------------------------------------------------ 05/05/2016 $12,505.30 Investigator Product Sponsored Trial ------------------------------------------------------------------------ 05/09/2016 $153,730.00 Investigator Product Sponsored Trial ------------------------------------------------------------------------ 05/09/2016 $51,015.00 Investigator Product Sponsored Trial ------------------------------------------------------------------------ 05/24/2016 $576,860.60 Investigator Product Sponsored Trial ------------------------------------------------------------------------ 05/25/2016 $117,405.00 Investigator Product Sponsored Trial ------------------------------------------------------------------------ 07/06/2016 $117,405.00 Investigator Product Sponsored Trial ------------------------------------------------------------------------ 07/13/2016 $352,185.00 Investigator Product Sponsored Trial ------------------------------------------------------------------------ 07/13/2016 $58,710.00 Investigator Product Sponsored Trial ------------------------------------------------------------------------ 07/25/2016 $11,312.95 Investigator Product Sponsored Trial ------------------------------------------------------------------------ 07/26/2016 $15,040.60 Investigator Product Sponsored Trial ------------------------------------------------------------------------ 07/26/2016 $21,998.88 Investigator Product Sponsored Trial ------------------------------------------------------------------------ 07/26/2016 $27,466.10 Investigator Product Sponsored Trial ------------------------------------------------------------------------ 07/26/2016 $24,981.00 Investigator Product Sponsored Trial ------------------------------------------------------------------------ 07/27/2016 $7,585.30 Investigator Product Sponsored Trial ------------------------------------------------------------------------ 07/27/2016 $27,963.12 Investigator Product Sponsored Trial ------------------------------------------------------------------------ 07/28/2016 $12,505.30 Investigator Product Sponsored Trial ------------------------------------------------------------------------ 08/31/2016 $12,930.00 Investigator Product Sponsored Trial ------------------------------------------------------------------------ 09/01/2016 $22,106.80 Investigator Product Sponsored Trial ------------------------------------------------------------------------ 09/14/2016 $3,103.89 Investigator Product Sponsored Trial ------------------------------------------------------------------------ 09/27/2016 $88,057.50 Investigator Product Sponsored Trial ------------------------------------------------------------------------ 10/10/2016 $72,120.70 Investigator Product Sponsored Trial ------------------------------------------------------------------------ 10/19/2016 $22,106.80 Investigator Product Sponsored Trial ------------------------------------------------------------------------ 10/24/2016 $12,505.30 Investigator Product Sponsored Trial ------------------------------------------------------------------------ 10/31/2016 $293,760.00 Investigator Product Sponsored Trial ------------------------------------------------------------------------ 10/31/2016 $58,764.00 Investigator Product Sponsored Trial ------------------------------------------------------------------------ 10/31/2016 $12,930.00 Investigator Product Sponsored Trial ------------------------------------------------------------------------ 10/31/2016 $58,764.00 Investigator Product Sponsored Trial ------------------------------------------------------------------------ 11/01/2016 $29,389.50 Investigator Product Sponsored Trial ------------------------------------------------------------------------ 11/15/2016 $77,933.40 Investigator Product Sponsored Trial ------------------------------------------------------------------------ 11/17/2016 $58,764.00 Investigator Product Sponsored Trial ------------------------------------------------------------------------ 11/21/2016 $19,265.00 Investigator Product Sponsored Trial ------------------------------------------------------------------------ 11/21/2016 $134,465.00 Investigator Product Sponsored Trial ------------------------------------------------------------------------ 12/14/2016 $88,138.50 Investigator Product Sponsored Trial ------------------------------------------------------------------------ 12/19/2016 $293,760.00 Investigator Product Sponsored Trial ------------------------------------------------------------------------ 04/05/2016 $382.26 Investigator Product Sponsored Trial ------------------------------------------------------------------------ 10/17/2016 $449.71 Investigator Product Sponsored Trial ------------------------------------------------------------------------ 05/09/2016 $1,122,210.00 Investigator Fees Sponsored Trial ------------------------------------------------------------------------ 12/08/2016 $1,122,209.00 Investigator Fees Sponsored Trial ------------------------------------------------------------------------ 02/16/2016 $59,187.50 Investigator Cash or Cash Sponsored Trial Equivalent ------------------------------------------------------------------------ 10/18/2016 $67,970.00 Investigator Cash or Cash Sponsored Trial Equivalent ------------------------------------------------------------------------ 01/26/2016 $19,474.93 Investigator Cash or Cash Sponsored Trial Equivalent ------------------------------------------------------------------------ 06/02/2016 $47,400.50 Investigator Cash or Cash Sponsored Trial Equivalent ------------------------------------------------------------------------ 12/13/2016 $47,400.50 Investigator Cash or Cash Sponsored Trial Equivalent ------------------------------------------------------------------------ 01/04/2017 $862.56 Investigator Product Sponsored Trial ------------------------------------------------------------------------ 01/10/2017 $12,930.00 Investigator Product Sponsored Trial ------------------------------------------------------------------------ 01/11/2017 $6,317.65 Investigator Product Sponsored Trial ------------------------------------------------------------------------ 01/16/2017 $862.56 Investigator Product Sponsored Trial ------------------------------------------------------------------------ 01/18/2017 $29,362.50 Investigator Product Sponsored Trial ------------------------------------------------------------------------ 01/24/2017 $11,247.95 Investigator Product Sponsored Trial ------------------------------------------------------------------------ 01/24/2017 $288.66 Investigator Product Sponsored Trial ------------------------------------------------------------------------ 01/24/2017 $11,247.95 Investigator Product Sponsored Trial ------------------------------------------------------------------------ 01/24/2017 $1,108.73 Investigator Product Sponsored Trial ------------------------------------------------------------------------ 01/24/2017 $19,945.80 Investigator Product Sponsored Trial ------------------------------------------------------------------------ 01/24/2017 $4,538.12 Investigator Product Sponsored Trial ------------------------------------------------------------------------ 01/24/2017 $13,549.36 Investigator Product Sponsored Trial ------------------------------------------------------------------------ 01/24/2017 $3,112.08 Investigator Product Sponsored Trial ------------------------------------------------------------------------ 01/24/2017 $24,916.00 Investigator Product Sponsored Trial ------------------------------------------------------------------------ 01/24/2017 $810.52 Investigator Product Sponsored Trial ------------------------------------------------------------------------ 02/08/2017 $884.54 Investigator Product Sponsored Trial ------------------------------------------------------------------------ 03/01/2017 $884.54 Investigator Product Sponsored Trial ------------------------------------------------------------------------ 03/13/2017 $25,730.00 Investigator Product Sponsored Trial ------------------------------------------------------------------------ 03/16/2017 $58,710.00 Investigator Product Sponsored Trial ------------------------------------------------------------------------ 03/29/2017 $6,317.65 Investigator Product Sponsored Trial ------------------------------------------------------------------------ 03/30/2017 $145,308.00 Investigator Product Sponsored Trial ------------------------------------------------------------------------ 04/06/2017 $58,710.00 Investigator Product Sponsored Trial ------------------------------------------------------------------------ 05/01/2017 $58,710.00 Investigator Product Sponsored Trial ------------------------------------------------------------------------ 05/08/2017 $45,402.40 Investigator Product Sponsored Trial ------------------------------------------------------------------------ 05/18/2017 $29,362.50 Investigator Product Sponsored Trial ------------------------------------------------------------------------ 05/25/2017 $29,362.50 Investigator Product Sponsored Trial ------------------------------------------------------------------------ 06/08/2017 $22,766.20 Investigator Product Sponsored Trial ------------------------------------------------------------------------ 06/12/2017 $22,766.20 Investigator Product Sponsored Trial ------------------------------------------------------------------------ 06/15/2017 $29,362.50 Investigator Product Sponsored Trial ------------------------------------------------------------------------ 06/15/2017 $29,362.50 Investigator Product Sponsored Trial ------------------------------------------------------------------------ 06/29/2017 $14,980.36 Investigator Product Sponsored Trial ------------------------------------------------------------------------ 07/05/2017 $58,710.00 Investigator Product Sponsored Trial ------------------------------------------------------------------------ 07/13/2017 $58,710.00 Investigator Product Sponsored Trial ------------------------------------------------------------------------ 07/17/2017 $58,710.00 Investigator Product Sponsored Trial ------------------------------------------------------------------------ 07/25/2017 $58,710.00 Investigator Product Sponsored Trial ------------------------------------------------------------------------ 07/25/2017 $19,945.80 Investigator Product Sponsored Trial ------------------------------------------------------------------------ 07/25/2017 $10,129.40 Investigator Product Sponsored Trial ------------------------------------------------------------------------ 07/25/2017 $10,194.40 Investigator Product Sponsored Trial ------------------------------------------------------------------------ 07/25/2017 $24,916.00 Investigator Product Sponsored Trial ------------------------------------------------------------------------ 07/25/2017 $2,413.36 Investigator Product Sponsored Trial ------------------------------------------------------------------------ 08/02/2017 $58,710.00 Investigator Product Sponsored Trial ------------------------------------------------------------------------ 08/15/2017 $15,220.80 Investigator Product Sponsored Trial ------------------------------------------------------------------------ 08/24/2017 $440,227.50 Investigator Product Sponsored Trial ------------------------------------------------------------------------ 09/20/2017 $30,311.60 Investigator Product Sponsored Trial ------------------------------------------------------------------------ 09/21/2017 $14,980.36 Investigator Product Sponsored Trial ------------------------------------------------------------------------ 10/18/2017 $58,710.00 Investigator Product Sponsored Trial ------------------------------------------------------------------------ 10/30/2017 $305,489.41 Investigator Product Sponsored Trial ------------------------------------------------------------------------ 11/29/2017 $6,855.86 Investigator Product Sponsored Trial ------------------------------------------------------------------------ 11/29/2017 $40,810.16 Investigator Product Sponsored Trial ------------------------------------------------------------------------ 12/18/2017 $162,934.69 Investigator Product Sponsored Trial ------------------------------------------------------------------------ 12/20/2017 $1,163,061.00 Investigator Fees Sponsored Trial ------------------------------------------------------------------------ 12/20/2017 $831,459.00 Investigator Fees Sponsored Trial ------------------------------------------------------------------------ 04/12/2017 $140,654.12 Investigator Fees Sponsored Trial ------------------------------------------------------------------------ 10/01/2017 $75,158.78 Investigator Fees Sponsored Trial ------------------------------------------------------------------------ 10/25/2017 $53,668.90 Investigator Fees Sponsored Trial ------------------------------------------------------------------------ 10/20/2017 $391,759.00 Investigator Fees Sponsored Trial ------------------------------------------------------------------------ 11/21/2017 $76,900.00 Investigator Fees Sponsored Trial ------------------------------------------------------------------------ 09/12/2017 $55,768.59 Investigator Fees Sponsored Trial ------------------------------------------------------------------------ 07/18/2017 $77,522.30 Investigator Cash or Cash Sponsored Trial Equivalent ------------------------------------------------------------------------ 03/02/2017 $7,955.33 Investigator Cash or Cash Sponsored Trial Equivalent ------------------------------------------------------------------------ 07/06/2017 $43,280.58 Investigator Cash or Cash Sponsored Trial Equivalent ------------------------------------------------------------------------ 01/17/2017 $244,633.00 Investigator Cash or Cash Sponsored Trial Equivalent ------------------------------------------------------------------------ 01/17/2017 $37,134.00 Investigator Cash or Cash Sponsored Trial Equivalent ------------------------------------------------------------------------ 02/21/2017 $6,000.00 Investigator Cash or Cash Sponsored Trial Equivalent ------------------------------------------------------------------------ 04/04/2017 $7,234.45 Investigator Cash or Cash Sponsored Trial Equivalent ------------------------------------------------------------------------ 05/23/2017 $50,279.75 Investigator Cash or Cash Sponsored Trial Equivalent ------------------------------------------------------------------------ 08/15/2017 $92,654.93 Investigator ................... Sponsored Trial Cash or Cash Equivalent ------------------------------------------------------------------------ 04/25/2017 $128,325.90 Investigator Cash or Cash Sponsored Trial Equivalent ------------------------------------------------------------------------ 07/18/2017 $128,325.90 Investigator Cash or Cash Sponsored Trial Equivalent ------------------------------------------------------------------------ 09/05/2017 $128,325.90 Investigator Cash or Cash Sponsored Trial Equivalent ------------------------------------------------------------------------ 11/07/2017 $128,325.90 Investigator Cash or Cash Sponsored Trial Equivalent ------------------------------------------------------------------------ 05/09/2017 $66,562.62 Investigator Cash or Cash Sponsored Trial Equivalent ------------------------------------------------------------------------ 07/06/2017 $66,562.62 Investigator Cash or Cash Sponsored Trial Equivalent ------------------------------------------------------------------------ 10/03/2017 $66,562.62 Investigator Cash or Cash Sponsored Trial Equivalent ------------------------------------------------------------------------ 05/02/2017 $80,715.00 Investigator Cash or Cash Sponsored Trial Equivalent ------------------------------------------------------------------------ 01/04/2017 $47,400.50 Investigator Cash or Cash Sponsored Trial Equivalent ------------------------------------------------------------------------ 01/04/2017 $47,400.97 Investigator Cash or Cash Sponsored Trial Equivalent ------------------------------------------------------------------------ 01/17/2017 $100,000.00 Investigator Cash or Cash Sponsored Trial Equivalent ------------------------------------------------------------------------ 03/02/2017 $26,701.00 Investigator Cash or Cash Sponsored Trial Equivalent ------------------------------------------------------------------------ 04/18/2017 $190,471.20 Investigator Cash or Cash Sponsored Trial Equivalent ------------------------------------------------------------------------ 08/15/2017 $2,100.00 Investigator Cash or Cash Sponsored Trial Equivalent ------------------------------------------------------------------------ 11/14/2017 $23,348.00 Investigator Cash or Cash Sponsored Trial Equivalent ------------------------------------------------------------------------ 05/30/2017 $140,654.12 Investigator Cash or Cash Sponsored Trial Equivalent ------------------------------------------------------------------------ 09/19/2017 $188,832.43 Investigator Cash or Cash Sponsored Trial Equivalent ------------------------------------------------------------------------ 12/05/2017 $2,835.71 Investigator Cash or Cash Sponsored Trial Equivalent ------------------------------------------------------------------------ 01/22/2018 $16,681.38 Investigator Product Sponsored Trial ------------------------------------------------------------------------ 01/22/2018 $427.27 Investigator Product Sponsored Trial ------------------------------------------------------------------------ 01/22/2018 $750.53 Investigator Product Sponsored Trial ------------------------------------------------------------------------ 01/23/2018 $15,679.17 Investigator Product Sponsored Trial ------------------------------------------------------------------------ 01/23/2018 $3,904.40 Investigator Product Sponsored Trial ------------------------------------------------------------------------ 01/23/2018 $12,928.50 Investigator Product Sponsored Trial ------------------------------------------------------------------------ 01/25/2018 $25,640.33 Investigator Product Sponsored Trial ------------------------------------------------------------------------ 01/25/2018 $1,118.37 Investigator Product Sponsored Trial ------------------------------------------------------------------------ 01/25/2018 $2,872.13 Investigator Product Sponsored Trial ------------------------------------------------------------------------ 01/29/2018 $712,788.63 Investigator Product Sponsored Trial ------------------------------------------------------------------------ 02/20/2018 $152,752.20 Investigator Product Sponsored Trial ------------------------------------------------------------------------ 04/11/2018 $314,348.09 Investigator Product Sponsored Trial ------------------------------------------------------------------------ 04/17/2018 $19,930.48 Investigator Product Sponsored Trial ------------------------------------------------------------------------ 05/22/2018 $261,959.23 Investigator Product Sponsored Trial ------------------------------------------------------------------------ 05/29/2018 $157,181.55 Investigator Product Sponsored Trial ------------------------------------------------------------------------ 07/10/2018 $16,302.40 Investigator Product Sponsored Trial ------------------------------------------------------------------------ 07/10/2018 $13,607.00 Investigator Product Sponsored Trial ------------------------------------------------------------------------ 07/12/2018 $17,650.10 Investigator Product Sponsored Trial ------------------------------------------------------------------------ 07/12/2018 $27,084.00 Investigator Product Sponsored Trial ------------------------------------------------------------------------ 07/17/2018 $209,570.39 Investigator Product Sponsored Trial ------------------------------------------------------------------------ 07/19/2018 $88,057.50 Investigator Product Sponsored Trial ------------------------------------------------------------------------ 08/14/2018 $58,710.00 Investigator Product Sponsored Trial ------------------------------------------------------------------------ 08/20/2018 $58,710.00 Investigator Product Sponsored Trial ------------------------------------------------------------------------ 08/23/2018 $117,405.00 Investigator Product Sponsored Trial ------------------------------------------------------------------------ 09/17/2018 $157,181.55 Investigator Product Sponsored Trial ------------------------------------------------------------------------ 09/27/2018 $157,181.55 Investigator Product Sponsored Trial ------------------------------------------------------------------------ 10/29/2018 $261,959.23 Investigator Product Sponsored Trial ------------------------------------------------------------------------ 11/28/2018 $58,710.00 Investigator Product Sponsored Trial ------------------------------------------------------------------------ 11/29/2018 $104,792.70 Investigator Product Sponsored Trial ------------------------------------------------------------------------ 11/26/2018 $348.48 Investigator Supplies Sponsored Trial ------------------------------------------------------------------------ 11/26/2018 $28.32 Investigator Supplies Sponsored Trial ------------------------------------------------------------------------ 04/25/2018 $67.25 Investigator Supplies Sponsored Trial ------------------------------------------------------------------------ 08/28/2018 $281.36 Investigator Supplies Sponsored Trial ------------------------------------------------------------------------ 11/27/2018 $793,755.00 Investigator Fees Sponsored Trial ------------------------------------------------------------------------ 09/24/2018 $277,130.00 Investigator Investigator Fees Sponsored Trial ------------------------------------------------------------------------ 10/19/2018 $207,848.00 Investigator Investigator Fees Sponsored Trial ------------------------------------------------------------------------ 03/20/2018 $26,125.00 Investigator Cash or Cash Sponsored Trial Equivalent ------------------------------------------------------------------------ 01/30/2018 $76,900.00 Investigator Cash or Cash Sponsored Trial Equivalent ------------------------------------------------------------------------ 06/12/2018 $29,796.00 Investigator Cash or Cash Sponsored Trial Equivalent ------------------------------------------------------------------------ 02/20/2018 $178,970.30 Investigator Cash or Cash Sponsored Trial Equivalent ------------------------------------------------------------------------ 01/16/2018 $244,633.00 Investigator Cash or Cash Sponsored Trial Equivalent ------------------------------------------------------------------------ 02/06/2018 $128,325.90 Investigator Cash or Cash Sponsored Trial Equivalent ------------------------------------------------------------------------ 09/06/2018 $128,325.90 Investigator Cash or Cash Sponsored Trial Equivalent ------------------------------------------------------------------------ 09/06/2018 $128,325.90 Investigator Cash or Cash Sponsored Trial Equivalent ------------------------------------------------------------------------ 04/19/2018 $66,562.62 Investigator Cash or Cash Sponsored Trial Equivalent ------------------------------------------------------------------------ 05/15/2018 $35,581.00 Investigator Cash or Cash Sponsored Trial Equivalent ------------------------------------------------------------------------ 05/15/2018 $30,030.00 Investigator Cash or Cash Sponsored Trial Equivalent ------------------------------------------------------------------------ 06/19/2018 $52,087.00 Investigator Cash or Cash Sponsored Trial Equivalent ------------------------------------------------------------------------ 07/23/2018 $31,131.00 Investigator Cash or Cash Sponsored Trial Equivalent ------------------------------------------------------------------------ 01/30/2018 $14,223.80 Investigator Cash or Cash Sponsored Trial Equivalent ------------------------------------------------------------------------ 04/03/2018 $144,601.03 Investigator Cash or Cash Sponsored Trial Equivalent ------------------------------------------------------------------------ 08/02/2018 $47,500.00 Investigator Cash or Cash Sponsored Trial Equivalent ------------------------------------------------------------------------ 08/02/2018 $148,734.45 Investigator Cash or Cash Sponsored Trial Equivalent ------------------------------------------------------------------------ 03/29/2018 $238,670.00 Investigator Cash or Cash Sponsored Trial Equivalent ------------------------------------------------------------------------ 04/05/2018 $104,418.67 Investigator Cash or Cash Sponsored Trial Equivalent ------------------------------------------------------------------------ 05/10/2018 $7,939.00 Investigator Cash or Cash Sponsored Trial Equivalent ------------------------------------------------------------------------ 11/26/2018 $14,624.00 Investigator Cash or Cash Sponsored Trial Equivalent ------------------------------------------------------------------------ 01/09/2018 $100,000.00 Investigator Cash or Cash Sponsored Trial Equivalent ------------------------------------------------------------------------ 01/02/2018 $53,668.90 Investigator Cash or Cash Sponsored Trial Equivalent ------------------------------------------------------------------------ 01/05/2018 $391,759.00 Investigator Cash or Cash Sponsored Trial Equivalent ------------------------------------------------------------------------ 05/08/2018 $28,610.89 Investigator Cash or Cash Sponsored Trial Equivalent ------------------------------------------------------------------------ 10/29/2018 $78,100.80 Investigator Cash or Cash Sponsored Trial Equivalent ------------------------------------------------------------------------ 08/21/2018 $29,796.00 Investigator Cash or Cash Sponsored Trial Equivalent ------------------------------------------------------------------------ 11/19/2018 $103,543.60 Investigator Cash or Cash Sponsored Trial Equivalent ------------------------------------------------------------------------ 11/19/2018 $97,510.18 Investigator Cash or Cash Sponsored Trial Equivalent ------------------------------------------------------------------------ 12/10/2018 $48,814.00 Investigator Cash or Cash Sponsored Trial Equivalent ------------------------------------------------------------------------ 11/19/2018 $72,000.00 Investigator Cash or Cash Sponsored Trial Equivalent ------------------------------------------------------------------------ ------------------------------------------------------------------------ Physician/ Teaching Address Hospital Name Line 1 City State ZIP Name of Study (NPI) ------------------------------------------------------------------------ Montefiore 111 EAST BRONX NY 10467 A roadmap for Medical 210TH the conversion Center STREET from sliding scale to basal insulin in the long term care setting. ------------------------------------------------------------------------ Langley Porter 405 SAN CA 94143 A Phase I Study Psychiatric PARNASUS FRANCI of Cabazitaxel, SCO Mitoxanthrone, and Prednison (CAMP) for Patients with Metastatic Castration- Resistant Prostate Cancer and no Prior Chemotherapy ------------------------------------------------------------------------ Memorial 1275 YORK NEW NY 10065 An Exploratory Hospital for AVENUE YORK Randomized Cancer and Phase II Allied Multicenter Diseases Trial of Abiraterone Acetate with or without Cabazitaxel in Treatment of Metastatic Castration Resistant Prostate Cancer ------------------------------------------------------------------------ University of 5841 SOUTH CHICAGO IL 60637 A study of the Chicago MARYLAND effects of Hospital AVENUE Alemtuzumab on Surrogate Markers of Disease Activity and Repair using Advanced MRI measures in Subjects with Relapsing Remitting Multiple Sclerosis. ------------------------------------------------------------------------ University of 5841 SOUTH CHICAGO IL 60637 A study of the Chicago MARYLAND effects of Hospital AVENUE Alemtuzumab on Surrogate Markers of Disease Activity and Repair using Advanced MRI measures in Subjects with Relapsing Remitting Multiple Sclerosis. ------------------------------------------------------------------------ University of 5841 SOUTH CHICAGO IL 60637 A study of the Chicago MARYLAND effects of Hospital AVENUE Alemtuzumab on Surrogate Markers of Disease Activity and Repair using Advanced MRI measures in Subjects with Relapsing Remitting Multiple Sclerosis. ------------------------------------------------------------------------ University of 5841 SOUTH CHICAGO IL 60637 A study of the Chicago MARYLAND effects of Hospital AVENUE Alemtuzumab on Surrogate Markers of Disease Activity and Repair using Advanced MRI measures in Subjects with Relapsing Remitting Multiple Sclerosis. ------------------------------------------------------------------------ University of 5841 SOUTH CHICAGO IL 60637 A study of the Chicago MARYLAND effects of Hospital AVENUE Alemtuzumab on Surrogate Markers of Disease Activity and Repair using Advanced MRI measures in Subjects with Relapsing Remitting Multiple Sclerosis. ------------------------------------------------------------------------ University of 5841 SOUTH CHICAGO IL 60637 A study of the Chicago MARYLAND effects of Hospital AVENUE Alemtuzumab on Surrogate Markers of Disease Activity and Repair using Advanced MRI measures in Subjects with Relapsing Remitting Multiple Sclerosis. ------------------------------------------------------------------------ University of 5841 SOUTH CHICAGO IL 60637 A study of the Chicago MARYLAND effects of Hospital AVENUE Alemtuzumab on Surrogate Markers of Disease Activity and Repair using Advanced MRI measures in Subjects with Relapsing Remitting Multiple Sclerosis. ------------------------------------------------------------------------ University of 5841 SOUTH CHICAGO IL 60637 A study of the Chicago MARYLAND effects of Hospital AVENUE Alemtuzumab on Surrogate Markers of Disease Activity and Repair using Advanced MRI measures in Subjects with Relapsing Remitting Multiple Sclerosis. ------------------------------------------------------------------------ University of 5841 SOUTH CHICAGO IL 60637 A study of the Chicago MARYLAND effects of Hospital AVENUE Alemtuzumab on Surrogate Markers of Disease Activity and Repair using Advanced MRI measures in Subjects with Relapsing Remitting Multiple Sclerosis. ------------------------------------------------------------------------ University of 5841 SOUTH CHICAGO IL 60637 A study of the Chicago MARYLAND effects of Hospital AVENUE Alemtuzumab on Surrogate Markers of Disease Activity and Repair using Advanced MRI measures in Subjects with Relapsing Remitting Multiple Sclerosis. ------------------------------------------------------------------------ University of 5841 SOUTH CHICAGO IL 60637 A study of the Chicago MARYLAND effects of Hospital AVENUE Alemtuzumab on Surrogate Markers of Disease Activity and Repair using Advanced MRI measures in Subjects with Relapsing Remitting Multiple Sclerosis. ------------------------------------------------------------------------ University of 5841 SOUTH CHICAGO IL 60637 A study of the Chicago MARYLAND effects of Hospital AVENUE Alemtuzumab on Surrogate Markers of Disease Activity and Repair using Advanced MRI measures in Subjects with Relapsing Remitting Multiple Sclerosis. ------------------------------------------------------------------------ University of 5841 SOUTH CHICAGO IL 60637 A study of the Chicago MARYLAND effects of Hospital AVENUE Alemtuzumab on Surrogate Markers of Disease Activity and Repair using Advanced MRI measures in Subjects with Relapsing Remitting Multiple Sclerosis. ------------------------------------------------------------------------ Keck Hospital 1500 SAN LOS CA 90033 Detection of of USC PABLO ANGELE early end-organ STREET S damage by endothelial dysfunction with reactive hyperemia- digital peripheral arterial tonometry in patients with Fabry disease ------------------------------------------------------------------------ University of 619 SOUTH BIRMING AL 35233 Improved Alabama 19TH HAM Detection, Hospital STREET Diagnosis, and Management of Fabry Disease through Serial Ophthalmic Documentation and Tear Fluid Analysis ------------------------------------------------------------------------ University of 5841 SOUTH CHICAGO IL 60637 A study of the Chicago MARYLAND effects of Hospital AVENUE Alemtuzumab on Surrogate Markers of Disease Activity and Repair using Advanced MRI measures in Subjects with Relapsing Remitting Multiple Sclerosis. ------------------------------------------------------------------------ University of 5841 SOUTH CHICAGO IL 60637 A study of the Chicago MARYLAND effects of Hospital AVENUE Alemtuzumab on Surrogate Markers of Disease Activity and Repair using Advanced MRI measures in Subjects with Relapsing Remitting Multiple Sclerosis. ------------------------------------------------------------------------ Brigham and 75 FRANCIS BOSTON MA 02115 Effects of an Womens STREET Intensive Hospital Intervention on Medication Adherence, Glycemic Control, and Readmission Rates in Patients with Type 2 Diabetes ------------------------------------------------------------------------ University of 2 SEATTLE WA 98195 FLuctuation Washington Reduction With Insulin and GLP- 1 Added Together (FLAT- SUGAR) ------------------------------------------------------------------------ Beth Israel 330 BOSTON MA 02215 Simplification Deaconess BROOKLINE of diabetes Medical AVENUE regimen in Center elderly patients using glargine ------------------------------------------------------------------------ Dana-Farber 450 BOSTON MA 02215 Phase I Study of Cancer BROOKLINE Plerixafor Institute AVE (AMD3100) and Bevacizumab for recurrent high- grade glioma ------------------------------------------------------------------------ Dana-Farber 450 BOSTON MA 02215 Phase I/II Trial Cancer BROOKLINE of Combination Institute AVE AMD3100 and Bortezomib in Relapsed or Relapsed/ Refractory Multiple Myeloma ------------------------------------------------------------------------ Dana-Farber 450 BOSTON MA 02215 Phase I/II Trial Cancer BROOKLINE of Combination Institute AVE AMD3100 and Bortezomib in Relapsed or Relapsed/ Refractory Multiple Myeloma ------------------------------------------------------------------------ Dana-Farber 450 BOSTON MA 02215 Taxotere Plus Cancer BROOKLINE Six-Month Institute AVE Androgen Suppression and Radiation Therapy vs Six- Month Androgen Suppression and Radiation Therapy for Patients with High-Risk Localized or Locally Advanced Prostate Cancer: A Randomized Controlled Trial ------------------------------------------------------------------------ UT MD Anderson 1515 HOUSTON TX 77030 Phase I/II Study Cancer Center HOLCOMBE of Plerixafor BLVD and Clofarabine in Previously Untreated Older (>= 60 years) Adult Patients with Acute Myelogenous Leukemia (AML) for Whom Standard Induction Chemotherapy is Unlikely to be of Benefit ------------------------------------------------------------------------ UT MD Anderson 1515 HOUSTON TX 77030 G-CSF and Cancer Center HOLCOMBE Plerixafor with BLVD Sorafenib for Acute Myelogenous Leukemia with FLT3(ITD) mutations ------------------------------------------------------------------------ UT MD Anderson 1515 HOUSTON TX 77030 Phase I/II Study Cancer Center HOLCOMBE of Plerixafor BLVD and Clofarabine in Previously Untreated Older (>= 60 years) Adult Patients with Acute Myelogenous Leukemia (AML) for Whom Standard Induction Chemotherapy is Unlikely to be of Benefit ------------------------------------------------------------------------ UT MD Anderson 1515 HOUSTON TX 77030 G-CSF and Cancer Center HOLCOMBE Plerixafor with BLVD Sorafenib for Acute Myelogenous Leukemia with FLT3(ITD) mutations ------------------------------------------------------------------------ Langley Porter 405 SAN CA 94143 A Phase III Psychiatric PARNASUS FRANCI Trial of Institute SCO Irinotecan/5-FU/ Leucovorin or Oxaliplatin/5- FU/leucovorin with Bevacizumab, or Cetuximab (C225) or with the Combination of Bevacizumab and Cetuximab for Patients with Untreated Metastatic Adenocarcinoma of the Colon or Rectum ------------------------------------------------------------------------ U of U 50 NORTH SALT UT 84132 Phase I/II Study Hospitals & MEDICAL LAKE of Low-Dose Clinic DRIVE CITY Oral Clofarabine for the treatment of IPSS INT-1, INT-2 or HIGH Myelodysplastic Syndromes (dysplastic type) Patients who have failed Hypomethylating Therapy ------------------------------------------------------------------------ Lehigh Valley 2100 MACK ALLENTO PA 18105 A Multicenter, (.) BLVD. 4TH WN Randomized, FLOOR Controlled FINANCE Trial Evaluating the Safety, Efficacy and Cost- Effectiveness of Seprafilm Adhesion Barrier Following Cesarean Section ------------------------------------------------------------------------ University of 5841 SOUTH CHICAGO IL 60637 A study of the Chicago MARYLAND effects of Hospital AVENUE Alemtuzumab on Surrogate Markers of Disease Activity and Repair using Advanced MRI measures in Subjects with Relapsing Remitting Multiple Sclerosis. ------------------------------------------------------------------------ University of 5841 SOUTH CHICAGO IL 60637 A study of the Chicago MARYLAND effects of Hospital AVENUE Alemtuzumab on Surrogate Markers of Disease Activity and Repair using Advanced MRI measures in Subjects with Relapsing Remitting Multiple Sclerosis. ------------------------------------------------------------------------ University of 5841 SOUTH CHICAGO IL 60637 A study of the Chicago MARYLAND effects of Hospital AVENUE Alemtuzumab on Surrogate Markers of Disease Activity and Repair using Advanced MRI measures in Subjects with Relapsing Remitting Multiple Sclerosis. ------------------------------------------------------------------------ University of 5841 SOUTH CHICAGO IL 60637 A study of the Chicago MARYLAND effects of Hospital AVENUE Alemtuzumab on Surrogate Markers of Disease Activity and Repair using Advanced MRI measures in Subjects with Relapsing Remitting Multiple Sclerosis. ------------------------------------------------------------------------ University of 5841 SOUTH CHICAGO IL 60637 A study of the Chicago MARYLAND effects of Hospital AVENUE Alemtuzumab on Surrogate Markers of Disease Activity and Repair using Advanced MRI measures in Subjects with Relapsing Remitting Multiple Sclerosis. ------------------------------------------------------------------------ Emory 1364 ATLANTA GA 30302 Do the Benefits University CLIFTON Outweigh the Hospital ROAD Risks? Assessing Patients' Perceptions of Newborn Screening for Lysosomal Storage Diseases ------------------------------------------------------------------------ Massachusetts FRUIT BOSTON MA 02114 Neuroimaging General STREET Characteristics Hospital in Fabry Disease: Quantitation of CNS White Matter Lesions ------------------------------------------------------------------------ Massachusetts FRUIT BOSTON MA 02114 Neuroimaging General STREET Characteristics Hospital in Fabry Disease: Quantitation of CNS White Matter Lesions ------------------------------------------------------------------------ Massachusetts FRUIT BOSTON MA 02114 Neuroimaging General STREET Characteristics Hospital in Fabry Disease: Quantitation of CNS White Matter Lesions ------------------------------------------------------------------------ University of 2 SEATTLE WA 98195 Podocyturia: A Washington Non-Invasive Biomarker of Fabry Nephropathy ------------------------------------------------------------------------ University of 2 SEATTLE WA 98195 Podocyturia: A Washington Non-Invasive Biomarker of Fabry Nephropathy ------------------------------------------------------------------------ University of 619 SOUTH BIRMING AL 35233 Cognitive Alabama 19TH HAM Function Hospital STREET Assessment in Fabry Disease: A Pilot Feasibility Study ------------------------------------------------------------------------ University of 619 SOUTH BIRMING AL 35233 Multi-center, Alabama 19TH HAM Open-label Hospital STREET Study of the Safety and Efficacy of Control of Proteinuria with ACE Inhibitors and ARBS in Patients with Fabry Disease Who Are Receiving Fabrazyme?: The Fabrazyme? + Arbs + ACE inhibitors Treatments (FAACET) Study: The FAACET Study. ------------------------------------------------------------------------ Rochester 1425 ROCHEST NY 14621 A Study General PORTLAND ER Evaluating Hospital AVENUE Acute Otitis Media and Nasopharyngeal Colonization Caused by Streptococcus pneumoniae in Healthy Children ------------------------------------------------------------------------ Dana-Farber 450 BOSTON MA 02215 Randomized Phase Cancer BROOKLINE II Study of Institute AVE FOLFOX +/- Aflibercept in metastatic esophagogastric cancer ------------------------------------------------------------------------ Dana-Farber 450 BOSTON MA 02215 Randomized Phase Cancer BROOKLINE II Study of Institute AVE FOLFOX +/- Aflibercept in metastatic esophagogastric cancer ------------------------------------------------------------------------ Dana-Farber 450 BOSTON MA 02215 Randomized Phase Cancer BROOKLINE II Study of Institute AVE FOLFOX +/- Aflibercept in metastatic esophagogastric cancer ------------------------------------------------------------------------ UT MD Anderson 1515 HOUSTON TX 77030 A Randomized Cancer Center HOLCOMBE Study of Once BLVD Daily Fludarabine- Clofarabine vs Fludarabine Alone Combined with IV Busulfan Followed by Allogeneic Hemopoietic Stem Cell Transplantation for AML and MDS ------------------------------------------------------------------------ UT MD Anderson 1515 HOUSTON TX 77030 A Randomized Cancer Center HOLCOMBE Study of Once BLVD Daily Fludarabine- Clofarabine vs Fludarabine Alone Combined with IV Busulfan Followed by Allogeneic Hemopoietic Stem Cell Transplantation for AML and MDS ------------------------------------------------------------------------ UT MD Anderson 1515 HOUSTON TX 77030 A Randomized Cancer Center HOLCOMBE Study of Once BLVD Daily Fludarabine- Clofarabine vs Fludarabine Alone Combined with IV Busulfan Followed by Allogeneic Hemopoietic Stem Cell Transplantation for AML and MDS ------------------------------------------------------------------------ UT MD Anderson 1515 HOUSTON TX 77030 A Randomized Cancer Center HOLCOMBE Study of Once BLVD Daily Fludarabine- Clofarabine vs Fludarabine Alone Combined with IV Busulfan Followed by Allogeneic Hemopoie ------------------------------------------------------------------------ UT MD Anderson 1515 HOUSTON TX 77030 A phase II study Cancer Center HOLCOMBE of cabazitaxel BLVD with or without carboplatin in patients with metastatic castration- resistant prostate cancer previously treated with docetaxel-based therapy. ------------------------------------------------------------------------ UT MD Anderson 1515 HOUSTON TX 77030 A phase II study Cancer Center HOLCOMBE of cabazitaxel BLVD with or without carboplatin in patients with metastatic castration- resistant prostate cancer previously treated with docetaxel-based therapy. ------------------------------------------------------------------------ Memorial 1275 YORK NEW NY 10065 An Exploratory Hospital For AVENUE YORK Randomized Center Phase II Multicenter Trial of Abiraterone Acetate with or without Cabazitaxel in Treatment of Metastatic Castration Resistant Prostate Cancer ------------------------------------------------------------------------ Brigham And 75 FRANCIS BOSTON MA 02115 Assessment of Womens STREET Aubagio?s Hospital neuroprotective effect on the development of T1 black holes ------------------------------------------------------------------------ Brigham And 75 FRANCIS BOSTON MA 02115 Assessment of Womens Hosp STREET Aubagio?s neuroprotective effect on the development of T1 black holes ------------------------------------------------------------------------ Brigham And 75 FRANCIS BOSTON MA 02115 Post-partum MRI Womens Hosp STREET Changes in Women with Multiple Sclerosis. ------------------------------------------------------------------------ Brigham And 75 FRANCIS BOSTON MA 02115 Post-partum MRI Womens Hosp STREET Changes in Women with Multiple Sclerosis. ------------------------------------------------------------------------ Brigham And 75 FRANCIS BOSTON MA 02115 Post-partum MRI Womens Hosp STREET Changes in Women with Multiple Sclerosis. ------------------------------------------------------------------------ Keck Hospital 1500 SAN LOS CA 90033 Detection of of USC PABLO ANGELE early end-organ STREET S damage by endothelial dysfunction with reactive hyperemia- digital peripheral arterial tonometry in patients with Fabry Disease ------------------------------------------------------------------------ Vanderbilt 1211 NASHVIL TN 37232 Innovation in University MEDICAL LE the timely Hospital CENTER diagnosis and DRIVE multidiscipinar y treatment of Fabry disease ------------------------------------------------------------------------ Emory 1364 ATLANTA GA 30302 A Prospective, University CLIFTON Multicenter Hospital ROAD Study Of Fabry Disease Clinical and Biochemical Findings in Young Pediatric Patients (The MOPPET Study) ------------------------------------------------------------------------ Emory 1364 ATLANTA GA 30302 Reproductive University CLIFTON Fitness in Hospital ROAD Individuals Affected by Fabry Disease (FIT) ------------------------------------------------------------------------ UCI Medical 101 CITY ORANGE CA 92868 Investigating Center (.) DRIVE Pompe SOUTH Prevalence in NEuromuscular Medicine Academic Practices (IPANEMA Study) ------------------------------------------------------------------------ Massachusetts FRUIT BOSTON MA 02114 The Fabry Pain General STREET Inventory: Hospital Validation of a New Clinical Tool to Comprehensively Capture the Fabry Pain Experience ------------------------------------------------------------------------ University of 2 SEATTLE WA 98195 Effects of Fabry Washington Disease on Myelination in the In Vivo Adult Human Brain ------------------------------------------------------------------------ University of 619 SOUTH BIRMING AL 35233 Improved Alabama 19TH HAM Detection, Hospital STREET Diagnosis, and Management of Fabry Disease through Serial Ophthalmic Documentation and Tear Fluid Analysis ------------------------------------------------------------------------ Dana-Farber 450 BOSTON MA 02215 Phase II Study Cancer BROOKLINE of Clofarabine Institute AVE in Patients with Recurrent or Refractory Langerhans Cell Histiocytosis ------------------------------------------------------------------------ Dana-Farber 450 BOSTON MA 02215 Phase I/II Trial Cancer BROOKLINE of Combination Institute AVE AMD3100 and Bortezomib in Relapsed or Relapsed/ Refractory Multiple Myeloma ------------------------------------------------------------------------ The Nebraska DEWEY OMAHA NE 68198 Leukine Medical AVENUE AT (sargramostim) Center 42ND for Parkinson's disease ------------------------------------------------------------------------ Charleston 501 MORRIS CHARLES WV 25326 A Phase II Trial Area Medical STREET TON of GM-CSF Protein plus Ipilimumab in Patients with Advanced Melanoma (ECOG 1608) ------------------------------------------------------------------------ City of Hope 1500 EAST DUARTE CA 91010 Phase II Study National DUARTE of Clofarabine Medical ROAD and High-Dose Center Melphalan Conditioning Prior to Allogeneic Heamtopoietic Cell Transplantation for Myelodysplasia ------------------------------------------------------------------------ The Christ 2139 AUBURN CINCINN OH 45219 A Phase II Trial Hospital AVENUE ATI of GM-CSF Protein plus Ipilimumab in Patients with Advanced Melanoma (ECOG 1608) ------------------------------------------------------------------------ Ohsu Hospital 3181 SAM PORTLAN OR 97239 A Phase I/II and Clinics JACKSON D Trial of (.) PARK ROAD Concurrent Chemohormonal Therapy Using Enzalutamide (MDV-3100) and Cabazitaxel in Patients with Metastatic Castration ------------------------------------------------------------------------ Memorial 1275 YORK NEW NY 10065 Creation of a Hospital for AVENUE YORK registry of Cancer and patients Allied treated on Diseases TAX3503 (101317743) ------------------------------------------------------------------------ Dana-Farber 450 BOSTON MA 02215 Phase I/II Trial Cancer BROOKLINE of Combination Institute (.) AVE AMD3100 and Bortezomib in Relapsed or Relapsed/ Refractory Multiple Myeloma ------------------------------------------------------------------------ Memorial 1275 YORK NEW NY 10065 An Exploratory Hospital for AVENUE YORK Randomized Cancer and Phase II Allied Multicenter Diseases Trial of (101317743) Abiraterone Acetate with or without Cabazitaxel in Treatment of Metastatic Castration ------------------------------------------------------------------------ UT MD Anderson 1515 HOUSTON TX 77030 A Randomized Cancer Center HOLCOMBE Phase 2 study (1083730964) BLVD to Evaluate the Efficacy of Rasburicase in Patients at Risk for TLS During Two Cycles of Chemotherapy ------------------------------------------------------------------------ The Miriam 164 SUMMIT PROVIDE RI 02906 Aflibercept Hospital (.) AVENUE NCE Maintenance for patients with resected or ablated metastatic colorectal cancer ------------------------------------------------------------------------ Memorial 1275 YORK NEW NY 10065 An Exploratory Hospital for AVENUE YORK Randomized Cancer and Phase II Allied Multicenter Diseases Trial of (101317743) Abiraterone Acetate with or without Cabazitaxel in Treatment of Metastatic Castration ------------------------------------------------------------------------ Memorial 1275 YORK NEW NY 10065 A Multi-center Hospital for AVENUE YORK Randomized Cancer and Phase II Study Allied of the Impact Diseases of CD34+ Cell (101317743) Dose on Progression- free Survival Following High- Dose Therapy ------------------------------------------------------------------------ Dana-Farber 450 BOSTON MA 02215 Phase I Study of Cancer BROOKLINE Plerixafor Institute (.) AVE (AMD3100) and Bevacizumab for Recurrent High- grade Glioma ------------------------------------------------------------------------ Emory 1364 ATLANTA GA 30302 A Prospective, University CLIFTON Multicenter Hospital ROAD Study Of Fabry (1073592747) Disease Clinical and Biochemical Findings in Young Pediatric Patients (The MOPPET Study) ------------------------------------------------------------------------ Vanderbilt 1211 NASHVIL TN 37232 Innovation in University MEDICAL LE the timely Hospitals & CENTER diagnosis and Clinic (.) DRIVE multidiscipinar y treatment of Fabry disease ------------------------------------------------------------------------ Emory 1364 ATLANTA GA 30302 Reproductive University CLIFTON Fitness in Hospital ROAD Individuals (1073592747) Affected by Fabry Disease (FIT) ------------------------------------------------------------------------ Emory 1364 ATLANTA GA 30302 Reproductive University CLIFTON Fitness in Hospital ROAD Individuals (1073592747) Affected by Fabry Disease (FIT) ------------------------------------------------------------------------ Massachusetts FRUIT BOSTON MA 02114 MGH Fabry General STREET Screening Hospital (.) Initiative ------------------------------------------------------------------------ Emory 1364 ATLANTA GA 30302 A Comparison of University CLIFTON Pharmacological Hospital ROAD vs. (1073592747) Psychological Interventions to Improve Adaptive Function in Fabry Patients Undergoing Enzyme Replace ------------------------------------------------------------------------ USC Norris 1441 LOS CA 90033 Detection of Cancer EASTLAKE ANGELE early end-organ Hospital (.) AVE S damage by endothelial dysfunction with reactive hyperemia- digital peripheral arterial tonometry in patients with Fabry Disease. ------------------------------------------------------------------------ Emory 1364 ATLANTA GA 30302 Online Social University CLIFTON Networking Use Hospital (.) ROAD Among Individuals Affected with Lysosomal Storage Diseases: ``Friend'' or Foe? ------------------------------------------------------------------------ Massachusetts FRUIT BOSTON MA 02114 Characterization General STREET and analysis of Hospital pathophysiology (1114196961) of the gastrointestina l complications of Fabry disease. ------------------------------------------------------------------------ Univ of MI 2301 ANN MI 48105 A Phase II Study Hospitals & COMMONWEAL ARBOR of VEGF-Trap Hlth Ctrs TH BLVD plus Modified (1043488760) FOLFOX 6 in Previously Untreated Patients with Metastatic Colorectal Cancer ------------------------------------------------------------------------ Cleveland 9500 EUCLID CLEVELA OH 44195 A Randomized, Clinic AVENUE ND Controlled, Hospital (.) open-labeled Clinical Trial of Thymoglobulin Induction and Extended Delay of Calcineurin Inhibitor Therapy for Rena ------------------------------------------------------------------------ Washington 110 IRVING WASHING DC 20010 Comparison of I- Hospital STREET NW TON 124 and I-131 Center Radiopharmacoki (1184638959) netics in Patients who have Well- differentiated Thyroid Cancer and have been Prepared with Radioactive Iodine 124 ------------------------------------------------------------------------ OHSU Hospital 3181 SAM PORTLAN OR 97239 A Phase I/II And Clinics JACKSON D Trial of (.) PARK ROAD Concurrent Chemohormonal Therapy Using Enzalutamide (MDV-3100) and Cabazitaxel in Patients with Metastatic Castration ------------------------------------------------------------------------ City Of Hope 1500 EAST DUARTE CA 91010 Phase II Study National DUARTE of Clofarabine Medical ROAD and High-Dose Center Melphalan (103343529) Conditioning Prior to Allogeneic Heamtopoietic Cell Transplantation for Myelodysplasia ------------------------------------------------------------------------ Massachusetts FRUIT BOSTON MA 02114 Phase II Study General STREET of Aflibercept Hospital (.) in Patients with Advanced, Progressive Carcinoid Tumors ------------------------------------------------------------------------ Vanderbilt 1211 NASHVIL TN 37232 Epidemiology of University MEDICAL LE Diabetes Hospitals & CENTER Interventions Clinic DRIVE and (1104202761) Complications ------------------------------------------------------------------------ City Of Hope 1500 EAST DUARTE CA 91010 Phase II Study National DUARTE of Clofarabine Medical ROAD and High-Dose Center Melphalan (103343529) Conditioning Prior to Allogeneic Heamtopoietic Cell Transplantation for Myelodysplasia ------------------------------------------------------------------------ Dana-Farber 450 BOSTON MA 02215 Phase II Study Cancer BROOKLINE of Clofarabine Institute (.) AVE in Patients with Recurrent or Refractory Langerhans Cell Histiocytosis ------------------------------------------------------------------------ Univ Of Iowa 200 HAWKINS IOWA IA 52242 Epidemiology of Hosp & Clinic DRIVE 1353 CITY Diabetes (.) JCP Interventions and Complications ------------------------------------------------------------------------ Univ of ONE COLUMBI MO 65212 Epidemiology of Missouri HOSPITAL A Diabetes Health Care DRIVE Interventions (1033499256) and Complications ------------------------------------------------------------------------ University Of 1959 NE SEATTLE WA 98195 Epidemiology of Washington PACIFIC ST Diabetes Med Ctr (.) Interventions and Complications ------------------------------------------------------------------------ Yale-New Haven 20 YORK NEW CT 06504 Epidemiology of Hospital (.) STREET HAVEN Diabetes Interventions and Complications ------------------------------------------------------------------------ University Of 22 SOUTH BATLIMO MD 21201 Epidemiology of Maryland Med GREENE RE Diabetes Sys STREET Interventions (1023304888) and Complications ------------------------------------------------------------------------ City Of Hope 1500 EAST DUARTE CA 91010 Phase II Study National DUARTE of Clofarabine Medical ROAD and High-Dose Center Melphalan (103343529) Conditioning Prior to Allogeneic Heamtopoietic Cell Transplantation for Myelodysplasia ------------------------------------------------------------------------ Charleston 501 MORRIS CHARLES WV 25326 A Phase II Trial Area Medical STREET TON of GM-CSF Center Inc. Protein plus (1124248752) Ipilimumab in Patients with Advanced Melanoma (ECOG 1608) ------------------------------------------------------------------------ Yale-New Haven 20 YORK NEW CT 06504 Eliglustat Hospital STREET HAVEN Tatrate Named (1003142225) Patient Program ------------------------------------------------------------------------ Memorial 1275 YORK NEW NY 10065 Safety and Hospital For AVENUE YORK Efficacy Trial Cancer And of Escalation Allied of Plerixafor Diseases for (101317743) Mobilization of CD34+ Hematopoietic Progenitor Cells and Evaluation of Globin Gene Traits ------------------------------------------------------------------------ Dana-Farber 450 BOSTON MA 02215 Phase II Study Cancer BROOKLINE of Clofarabine Institute (.) AVE in Patients with Recurrent or Refractory Langerhans Cell Histiocytosis ------------------------------------------------------------------------ Massachusetts FRUIT BOSTON MA 02114 Phase II Study General STREET of Aflibercept Hospital (.) in Patients with Advanced, Progressive Carcinoid Tumors ------------------------------------------------------------------------ Univ Of MI 2301 ANN MI 48105 A Phase II Study Hospitals & COMMONWEAL ARBOR of VEGF-Trap Hlth Ctrs TH BLVD plus Modified (1043488760) FOLFOX 6 in Previously Untreated Patients with Metastatic Colorectal Cancer ------------------------------------------------------------------------ University 445 LENOX BROOKLY NY 11203 A Phase II Study Hospital Of ROAD N of VEGF-Trap Brooklyn (.) plus Modified FOLFOX 6 in Previously Untreated Patients with Metastatic Colorectal Cancer ------------------------------------------------------------------------ Washington 110 IRVING WASHING DC 20010 Comparison of I- Hospital STREET NW TON 124 and I-131 Center Radiopharmacoki (1184638959) netics in Patients who have Well- differentiated Thyroid Cancer and have been Prepared with Radioactive Iodine 124 ------------------------------------------------------------------------ University 445 LENOX BROOKLY NY 11203 A Phase II Study Hospital Of ROAD N of VEGF-Trap Brooklyn (.) plus Modified FOLFOX 6 in Previously Untreated Patients with Metastatic Colorectal Cancer ------------------------------------------------------------------------ Dana-Farber 450 BOSTON MA 02215 Phase II Study Cancer BROOKLINE of Clofarabine Institute (.) AVE in Patients with Recurrent or Refractory Langerhans Cell Histiocytosis ------------------------------------------------------------------------ OHSU Hospital 3181 SAM PORTLAN OR 97239 A Phase I/II And Clinics JACKSON D Trial of (.) PARK ROAD Concurrent Chemohormonal Therapy Using Enzalutamide (MDV-3100) and Cabazitaxel in Patients with Metastatic Castration ------------------------------------------------------------------------ Univ Of MI 2301 ANN MI 48105 A Phase II Study Hospitals & COMMONWEAL ARBOR of VEGF-Trap Hlth Ctrs TH BLVD plus Modified (1043488760) FOLFOX 6 in Previously Untreated Patients with Metastatic Colorectal Cancer ------------------------------------------------------------------------ Charleston 501 MORRIS CHARLES WV 25326 A Phase II Trial Area Medical STREET TON of GM-CSF Center Inc. Protein plus (1124248752) Ipilimumab in Patients with Advanced Melanoma (ECOG 1608) ------------------------------------------------------------------------ Univ Of MI 2301 ANN MI 48105 A Phase II Study Hospitals & COMMONWEAL ARBOR of VEGF-Trap Hlth Ctrs TH BLVD plus Modified (1043488760) FOLFOX 6 in Previously Untreated Patients with Metastatic Colorectal Cancer ------------------------------------------------------------------------ Yale-New Haven 20 YORK NEW CT 06504 Eliglustat Hospital STREET HAVEN Tatrate Named (1003142225) Patient Program ------------------------------------------------------------------------ Memorial 1275 YORK NEW NY 10065 A Multi-center Hospital For AVENUE YORK Randomized Cancer And Phase II Study Allied of the Impact Diseases of CD34+ Cell (101317743) Dose on Progression- free Survival Following High- Dose Therapy and Autologous Stem-cell Rescue ------------------------------------------------------------------------ Lucile 725 WELCH PALO CA 94304 AML08: A Phase Packard ROAD ALTO III randomized Childrens trial of Hospital clofarabine (1003929852) plus cytarabine versus conventional induction therapy and of natural killer cell transplantation ------------------------------------------------------------------------ City Of Hope 1500 EAST DUARTE CA 91010 Phase II Study National DUARTE of Clofarabine Medical ROAD and High-Dose Center Melphalan (103343529) Conditioning Prior to Allogeneic Heamtopoietic Cell Transplantation for Myelodysplasia ------------------------------------------------------------------------ City Of Hope 1500 EAST DUARTE CA 91010 Phase II Study National DUARTE of Clofarabine Medical ROAD and High-Dose Center Melphalan (103343529) Conditioning Prior to Allogeneic Heamtopoietic Cell Transplantation for Myelodysplasia ------------------------------------------------------------------------ Texas 6621 FANNIN HOUSTON TX 77030 Phase II Study Childrens of Clofarabine Hospital (.) in Patients with Recurrent or Refractory Langerhans Cell Histiocytosis ------------------------------------------------------------------------ Univ Of Iowa 200 HAWKINS IOWA IA 52242 Epidemiology of Hosp & Clinic DRIVE 1353 CITY Diabetes (.) JCP Interventions and Complications ------------------------------------------------------------------------ Rainbow Babies 11100 CLEVELA OH 44106 Epidemiology of & Childrens EUCLID ND Diabetes Hospital AVENUE Interventions (1013954395) and Complications ------------------------------------------------------------------------ Univ Of ONE COLUMBI MO 65212 Epidemiology of Missouri HOSPITAL A Diabetes Health Care DRIVE Interventions (1033499256) and Complications ------------------------------------------------------------------------ University Of 1959 NE SEATTLE WA 98195 Epidemiology of Washington PACIFIC ST Diabetes Med Ctr (.) Interventions and Complications ------------------------------------------------------------------------ Yale-New Haven 20 YORK NEW CT 06504 Epidemiology of Hospital (.) STREET HAVEN Diabetes Interventions and Complications ------------------------------------------------------------------------ Mayo Clinic 1216 SECOND ROCHEST MN 55905 Epidemiology of Hospital STREET SW ER Diabetes Rochester (.) Interventions and Complications ------------------------------------------------------------------------ University Of 22 SOUTH BATLIMO MD 21201 Epidemiology of Maryland Med GREENE RE Diabetes Sys STREET Interventions (1023304888) and Complications ------------------------------------------------------------------------ Charleston 501 MORRIS CHARLES WV 25326 A Phase II Trial Area Medical STREET TON of GM-CSF Center Inc. Protein plus (1124248752) Ipilimumab in Patients with Advanced Melanoma (ECOG 1608) ------------------------------------------------------------------------ Massachusetts FRUIT BOSTON MA 02114 Phase II Study General STREET of Aflibercept Hospital (.) in Patients with Advanced, Progressive Carcinoid Tumors ------------------------------------------------------------------------ Cleveland 9500 EUCLID CLEVELA OH 44195 A Randomized, Clinic AVENUE ND Controlled, Hospital (.) open-labeled Clinical Trial of Thymoglobulin Induction and Extended Delay of Calcineurin Inhibitor Therapy for Renal Failure ------------------------------------------------------------------------ Washington 110 IRVING WASHING DC 20010 Comparison of I- Hospital STREET NW TON 124 and I-131 Center Radiopharmacoki (1184638959) netics in Patients who have Well- differentiated Thyroid Cancer and have been Prepared with Radioactive Iodine 124 ------------------------------------------------------------------------ City Of Hope 1500 EAST DUARTE CA 91010 Phase II Study National DUARTE of Clofarabine Medical ROAD and High-Dose Center Melphalan (103343529) Conditioning Prior to Allogeneic Heamtopoietic Cell Transplantation for Myelodysplasia ------------------------------------------------------------------------ Memorial 1275 YORK NEW NY 10065 Safety and Hospital For AVENUE YORK Efficacy Trial Cancer And of Escalation Allied of Plerixafor Diseases for (101317743) Mobilization of CD34+ Hematopoietic Progenitor Cells and Evaluation of Globin Gene Traits ------------------------------------------------------------------------ Cleveland 9500 EUCLID CLEVELA OH 44195 A Randomized, Clinic AVENUE ND Controlled, Hospital (.) open-labeled Clinical Trial of Thymoglobulin Induction and Extended Delay of Calcineurin Inhibitor Therapy for Renal Failure ------------------------------------------------------------------------ Charleston 501 MORRIS CHARLES WV 25326 A Phase II Trial Area Medical STREET TON of GM-CSF Center Inc. Protein plus (1124248752) Ipilimumab in Patients with Advanced Melanoma (ECOG 1608) ------------------------------------------------------------------------ City Of Hope 1500 EAST DUARTE CA 91010 Phase II Study National DUARTE of Clofarabine Medical ROAD and High-Dose Center Melphalan (103343529) Conditioning Prior to Allogeneic Heamtopoietic Cell Transplantation for Myelodysplasia ------------------------------------------------------------------------ Texas 6621 FANNIN HOUSTON TX 77030 Phase II Study Childrens of Clofarabine Hospital (.) in Patients with Recurrent or Refractory Langerhans Cell Histiocytosis ------------------------------------------------------------------------ Massachusetts FRUIT BOSTON MA 02114 Phase II Study General STREET of Aflibercept Hospital (.) in Patients with Advanced, Progressive Carcinoid Tumors ------------------------------------------------------------------------ Cook Childrens 901 SEVENTH FORT TX 76104 AML08: A Phase Medical AVENUE WORTH III randomized Center trial of (1215907530) clofarabine plus cytarabine versus conventional induction therapy and of natural killer cell transplantation ------------------------------------------------------------------------ Texas 6621 FANNIN HOUSTON TX 77030 Phase II Study Childrens of Clofarabine Hospital (.) in Patients with Recurrent or Refractory Langerhans Cell Histiocytosis ------------------------------------------------------------------------ Ohsu Hospital 3181 SAM PORTLAN OR 97239 A Phase I/II And Clinics JACKSON D Trial of (.) PARK ROAD Concurrent Chemohormonal Therapy Using Enzalutamide (MDV-3100) and Cabazitaxel in Patients with Metastatic Castration ------------------------------------------------------------------------ Texas 6621 FANNIN HOUSTON TX 77030 Phase II Study Childrens of Clofarabine Hospital (.) in Patients with Recurrent or Refractory Langerhans Cell Histiocytosis ------------------------------------------------------------------------ Univ Of Mi 2301 ANN MI 48105 A Phase II Study Hospitals & COMMONWEAL ARBOR of VEGF-Trap Hlth Ctrs TH BLVD plus Modified (1043488760) FOLFOX 6 in Previously Untreated Patients with Metastatic Colorectal Cancer ------------------------------------------------------------------------ Univ Of MI 2301 ANN MI 48105 A Phase II Study Hospitals & COMMONWEAL ARBOR of VEGF-Trap Hlth Ctrs TH BLVD plus Modified (1043488760) FOLFOX 6 in Previously Untreated Patients with Metastatic Colorectal Cancer ------------------------------------------------------------------------ Lucile Packard 725 WELCH PALO CA 94304 AML08: A Phase Childrens ROAD ALTO III randomized Hospital trial of (1003929852) clofarabine plus cytarabine versus conventional induction therapy and of natural killer cell transplantation ------------------------------------------------------------------------ City Of Hope 1500 EAST DUARTE CA 91010 Phase II Study National DUARTE of Clofarabine Medical ROAD and High-Dose Center Melphalan (103343529) Conditioning Prior to Allogeneic Heamtopoietic Cell Transplantation for Myelodysplasia ------------------------------------------------------------------------ Emory 1364 ATLANTA GA 30302 Enhancing Anti- University CLIFTON Myeloma Vaccine Hospital ROAD Response after (1073837167) Autologous Stem Cell Transplantation ------------------------------------------------------------------------ Emory 1364 ATLANTA GA 30302 MTA for : University CLIFTON Enhancing Anti- Hospital (.) ROAD Myeloma Vaccine Response after Autologous Stem Cell Transplant ------------------------------------------------------------------------ Rochester 1425 ROCHEST NY 14621 A Study General PORTLAND ER Evaluating Hospital (.) AVENUE Acute Otitis Media and Nasopharyngeal Colonization Caused by Streptococcus pneumoniae in Healthy Children ------------------------------------------------------------------------ Rochester 1425 ROCHEST NY 14621 A Study General PORTLAND ER Evaluating Hospital (.) AVENUE Acute Otitis Media and Nasopharyngeal Colonization Caused by Streptococcus pneumoniae in Healthy Children ------------------------------------------------------------------------ Brigham And 75 FRANCIS BOSTON MA 02115 Assessment of Womens STREET Aubagio?s Hospital (.) neuroprotective effect on the development of T1 black holes ------------------------------------------------------------------------ Brigham And 75 FRANCIS BOSTON MA 02115 miRNA profiling Womens STREET in Hospital Teriflunomide (1013935550) (Aubagio) treated patients ------------------------------------------------------------------------ Langley Porter 405 SAN CA 94143 Long-term Psychiatric PARNASUS FRANCI Management of Hosptial (.) SCO ?Younger, Active? Patients with Pain from Early Knee Osteoarthritis with Synvisc- One (hylan G-F 20) ------------------------------------------------------------------------ University Of 1959 NE SEATTLE WA 98195 Fluctuation Washington PACIFIC ST Reduction With Med Ctr (.) Insulin and GLP- 1 Added Together (FLAT- SUGAR) ------------------------------------------------------------------------ University Of 1959 NE SEATTLE WA 98195 Fluctuation Washington PACIFIC ST Reduction With Med Ctr (.) Insulin and GLP- 1 Added Together (FLAT- UGAR) ------------------------------------------------------------------------ Cleveland 9500 EUCLID CLEVELA OH 44195 A Randomized, Clinic AVENUE ND Controlled, Hospital open-labeled (1043549397) Clinical Trial of Thymoglobulin Induction and Extended Delay of Calcineurin Inhibitor Therapy for Renal Failure ------------------------------------------------------------------------ Massachusetts FRUIT BOSTON MA 02114 Phase II Study General STREET of Aflibercept Hospital in Patients (1114196961) with Advanced, Progressive Carcinoid Tumors ------------------------------------------------------------------------ Charleston 501 MORRIS CHARLES WV 25326 A Phase II Trial Area Medical STREET TON of GM-CSF Center Inc. Protein plus (1124248752) Ipilimumab in Patients with Advanced Melanoma (ECOG 1608) ------------------------------------------------------------------------ Cleveland 9500 EUCLID CLEVELA OH 44195 A Randomized, Clinic AVENUE ND Controlled, Hospital open-labeled (1043549397) Clinical Trial of Thymoglobulin Induction and Extended Delay of Calcineurin Inhibitor Therapy for Renal Failure ------------------------------------------------------------------------ Mount Sinai ONE GUSTAVE NEW NY 10029 Phase II Study Hospital L. LEVY YORK of Clofarabine (1003063280) PLACE in Patients with Recurrent or Refractory Langerhans Cell Histiocytosis ------------------------------------------------------------------------ Mayo Clinic 1216 SECOND ROCHEST MN 55905 Epidemiology of Hospital STREET SW ER Diabetes Rochester (.) Interventions and Complications ------------------------------------------------------------------------ Mayo Clinic 1216 SECOND ROCHEST MN 55905 Epidemiology of Hospital STREET SW ER Diabetes Rochester (.) Interventions and Complications ------------------------------------------------------------------------ University Of 200 HAWKINS IOWA IA 52242 Epidemiology of Iowa Hosp & DRIVE 1353 CITY Diabetes Clinics JCP Interventions (1326474149) and Complications ------------------------------------------------------------------------ University Of 200 HAWKINS IOWA IA 52242 Epidemiology of Iowa Hosp & DRIVE 1353 CITY Diabetes Clinics JCP Interventions (1326474149) and Complications ------------------------------------------------------------------------ Univ Of ONE COLUMBI MO 65212 Epidemiology of Missouri HOSPITAL A Diabetes Health Care DRIVE Interventions (1033499256) and Complications ------------------------------------------------------------------------ Univ Of ONE COLUMBI MO 65212 Epidemiology of Missouri HOSPITAL A Diabetes Health Care DRIVE Interventions (1033499256) and Complications ------------------------------------------------------------------------ Vanderbilt 1211 NASHVIL TN 37232 Epidemiology of University MEDICAL LE Diabetes Medical CENTER Interventions Center DRIVE and (1104202761) Complications ------------------------------------------------------------------------ Yale-New Haven 20 YORK NEW CT 06504 Epidemiology of Hospital STREET HAVEN Diabetes (1003142225) Interventions and Complications ------------------------------------------------------------------------ University Of 22 SOUTH BATLIMO MD 21201 Epidemiology of Maryland Med GREENE RE Diabetes Sys STREET Interventions (1023304888) and Complications ------------------------------------------------------------------------ University Of 22 SOUTH BATLIMO MD 21201 Epidemiology of Maryland Med GREENE RE Diabetes Sys STREET Interventions (1023304888) and Complications ------------------------------------------------------------------------ Cleveland 9500 EUCLID CLEVELA OH 44195 A Randomized, Clinic AVENUE ND Controlled, Hospital open-labeled (1043549397) Clinical Trial of Thymoglobulin Induction and Extended Delay of Calcineurin Inhibitor Therapy for Renal Failure ------------------------------------------------------------------------ Cleveland 9500 EUCLID CLEVELA OH 44195 A Randomized, Clinic AVENUE ND Controlled, Hospital open-labeled (1043549397) Clinical Trial of Thymoglobulin Induction and Extended Delay of Calcineurin Inhibitor Therapy for Renal Failure ------------------------------------------------------------------------ Massachusetts FRUIT BOSTON MA 02114 Phase II Study General STREET of Aflibercept Hospital in Patients (1114196961) with Advanced, Progressive Carcinoid Tumors ------------------------------------------------------------------------ Texas 6621 FANNIN HOUSTON TX 77030 Phase II Study Childrens of Clofarabine Hospital in Patients (1013283159) with Recurrent or Refractory Langerhans Cell Histiocytosis ------------------------------------------------------------------------ Charleston 501 MORRIS CHARLES WV 25326 A Phase II Trial Area Medical STREET TON of GM-CSF Center Inc. Protein plus (1124248752) Ipilimumab in Patients with Advanced Melanoma (ECOG 1608) ------------------------------------------------------------------------ Methodist 7700 FLOYD SAN TX 78229 A Multi-center Hospital CURL DRIVE ANTONI Randomized (1124074273) O Phase II Study of the Impact of CD34+ Cell Dose on Progression- free Survival Following High- Dose Therapy and Autologous Stem-cell Rescue ------------------------------------------------------------------------ Texas 6621 FANNIN HOUSTON TX 77030 Phase II Study Childrens of Clofarabine Hospital in Patients (1013283159) with Recurrent or Refractory Langerhans Cell Histiocytosis ------------------------------------------------------------------------ Massachusetts FRUIT BOSTON MA 02114 Phase II Study General STREET of Clofarabine Hospital in Patients (1114196961) with Recurrent or Refractory Langerhans Cell Histiocytosis ------------------------------------------------------------------------ Cleveland 9500 EUCLID CLEVELA OH 44195 A Randomized, Clinic AVENUE ND Controlled, Hospital open-labeled (1013392125) Clinical Trial of Thymoglobulin Induction and Extended Delay of Calcineurin Inhibitor Therapy for Renal Failure ------------------------------------------------------------------------ Texas 6621 FANNIN HOUSTON TX 77030 Phase II Study Childrens of Clofarabine Hospital in Patients (1013283159) with Recurrent or Refractory Langerhans Cell Histiocytosis ------------------------------------------------------------------------ Arkansas 1 CHILDRENS LITTLE AR 72202 Phase II Study Childrens WAY ROCK of Clofarabine Hospital in Patients (1134155831) with Recurrent or Refractory Langerhans Cell Histiocytosis ------------------------------------------------------------------------ Cleveland 9500 EUCLID CLEVELA OH 44195 A Randomized, Clinic AVENUE ND Controlled, Hospital open-labeled (1013392125) Clinical Trial of Thymoglobulin Induction and Extended Delay of Calcineurin Inhibitor Therapy for Renal Failure ------------------------------------------------------------------------ Cleveland 9500 EUCLID CLEVELA OH 44195 A Randomized, Clinic AVENUE ND Controlled, Hospital open-labeled (1013392125) Clinical Trial of Thymoglobulin Induction and Extended Delay of Calcineurin Inhibitor Therapy for Renal Failure ------------------------------------------------------------------------ Texas 6621 FANNIN HOUSTON TX 77030 Phase II Study Childrens of Clofarabine Hospital in Patients (1013283159) with Recurrent or Refractory Langerhans Cell Histiocytosis ------------------------------------------------------------------------ Texas 6621 FANNIN HOUSTON TX 77030 Phase II Study Childrens of Clofarabine Hospital in Patients (1013283159) with Recurrent or Refractory Langerhans Cell Histiocytosis ------------------------------------------------------------------------ Charleston 501 MORRIS CHARLES WV 25326 A Phase II Trial Area Medical STREET TON of GM-CSF Center Inc. Protein plus (1124248752) Ipilimumab in Patients with Advanced Melanoma (ECOG 1608) ------------------------------------------------------------------------ Phoenix 1919 E. PHOENIX AZ 85016 Phase II Study Childrens THOMAS of Clofarabine Hospital ROAD in Patients (1023475506) with Recurrent or Refractory Langerhans Cell Histiocytosis ------------------------------------------------------------------------ Texas 6621 FANNIN HOUSTON TX 77030 Phase II Study Childrens of Clofarabine Hospital in Patients (1013283159) with Recurrent or Refractory Langerhans Cell Histiocytosis ------------------------------------------------------------------------ Texas 6621 FANNIN HOUSTON TX 77030 Phase II Study Childrens of Clofarabine Hospital in Patients (1013283159) with Recurrent or Refractory Langerhans Cell Histiocytosis ------------------------------------------------------------------------ Texas 6621 FANNIN HOUSTON TX 77030 Phase II Study Childrens of Clofarabine Hospital in Patients (1013283159) with Recurrent or Refractory Langerhans Cell Histiocytosis ------------------------------------------------------------------------ Univ Of ONE COLUMBI MO 65212 Epidemiology of Missouri HOSPITAL A Diabetes Health Care DRIVE Interventions (1033499256) and Complications ------------------------------------------------------------------------ Univ Of ONE COLUMBI MO 65212 Epidemiology of Missouri HOSPITAL A Diabetes Health Care DRIVE Interventions (1033499256) and Complications ------------------------------------------------------------------------ Yale-New Haven 20 YORK NEW CT 06504 Epidemiology of Hospital STREET HAVEN Diabetes (1003142225) Interventions and Complications ------------------------------------------------------------------------ University Of 22 SOUTH BATLIMO MD 21201 Epidemiology of Maryland Med GREENE RE Diabetes Sys STREET Interventions (1023304888) and Complications ------------------------------------------------------------------------ University Of 22 SOUTH BATLIMO MD 21201 Epidemiology of Maryland Med GREENE RE Diabetes Sys STREET Interventions (1023304888) and Complications ------------------------------------------------------------------------ Massachusetts FRUIT BOSTON MA 02114 Phase II Study General STREET of Clofarabine Hospital in Patients (1114196961) with Recurrent or Refractory Langerhans Cell Histiocytosis ------------------------------------------------------------------------ Cleveland 9500 EUCLID CLEVELA OH 44195 A Randomized, Clinic AVENUE ND Controlled, Hospital open-labeled (1013392125) Clinical Trial of Thymoglobulin Induction and Extended Delay of Calcineurin Inhibitor Therapy for Renal Failure ------------------------------------------------------------------------ City Of Hope 1500 E. DUARTE CA 91010 Phase II Study National DUARTE of Clofarabine Medical Cnt ROAD and High-Dose (1033435292) Melphalan Conditioning Prior to Allogeneic Heamtopoietic Cell Transplantation for Myelodysplasia ------------------------------------------------------------------------ Cleveland 9500 EUCLID CLEVELA OH 44195 A Randomized, Clinic AVENUE ND Controlled, Hospital open-labeled (1013392125) Clinical Trial of Thymoglobulin Induction and Extended Delay of Calcineurin Inhibitor Therapy for Renal Failure ------------------------------------------------------------------------ Charleston 501 MORRIS CHARLES WV 25326 A Phase II Trial Area Medical STREET TON of GM-CSF Center Inc. Protein plus (1124248752) Ipilimumab in Patients with Advanced Melanoma (ECOG 1608) ------------------------------------------------------------------------ Phoenix 1919 E. PHOENIX AZ 85016 Phase II Study Childrens THOMAS of Clofarabine Hospital ROAD in Patients (1023475506) with Recurrent or Refractory Langerhans Cell Histiocytosis ------------------------------------------------------------------------ Mount Sinai ONE GUSTAVE NEW NY 10029 Clinical Trial Hospital (.) L. LEVY YORK of a Rapidly PLACE Cycling, Non- Cross Reactive Regimen of Approved Therapeutic Agents to Treat Prostate Cancer ------------------------------------------------------------------------ Cleveland 9500 EUCLID CLEVELA OH 44195 A Randomized, Clinic AVENUE ND Controlled, Hospital open-labeled (1013392125) Clinical Trial of Thymoglobulin Induction and Extended Delay of Calcineurin Inhibitor Therapy for Renal Failure ------------------------------------------------------------------------ Cleveland 9500 EUCLID CLEVELA OH 44195 A Randomized, Clinic AVENUE ND Controlled, Hospital open-labeled (1013392125) Clinical Trial of Thymoglobulin Induction and Extended Delay of Calcineurin Inhibitor Therapy for Renal Failure ------------------------------------------------------------------------ Ohsu Hospital 3181 SAM PORTLAN OR 97239 A Phase I/II And Clinics JACKSON D Trial of (.) PARK ROAD Concurrent Chemohormonal Therapy Using Enzalutamide (MDV-3100) and Cabazitaxel in Patients with Metastatic Castration ------------------------------------------------------------------------ Rochester 1425 ROCHEST NY 14621 A Study General PORTLAND ER Evaluating Hospital AVENUE Acute Otitis (1023105376) Media and Nasopharyngeal Colonization Caused by Streptococcus pneumoniae in Healthy Children ------------------------------------------------------------------------ Rochester 1425 ROCHEST NY 14621 A Study General PORTLAND ER Evaluating Hospital AVENUE Acute Otitis (1023105376) Media and Nasopharyngeal Colonization Caused by Streptococcus pneumoniae in Healthy Children ------------------------------------------------------------------------ Emory 1364 ATLANTA GA 30302 Glargine U300 University CLIFTON Hospital Trial: Hospital (.) ROAD A Randomized Controlled Trial Comparing Glargine U300 and Glargine U100 for the Inpatient and Post-Hospital Discharge ------------------------------------------------------------------------ Cleveland 9500 EUCLID CLEVELA OH 44195 Investigating Clinic AVENUE ND the efficacy of Hospital (.) Synvisc-One (Hylan-GF 20 6ml ) as adjunctive therapy for patients with knee osteo- arthritis or requiring physical therapy ------------------------------------------------------------------------ Massachusetts FRUIT BOSTON MA 02114 Enzyme General STREET Replacement Hospital Therapy and (1114196961) Podocyte Function ------------------------------------------------------------------------ Massachusetts FRUIT BOSTON MA 02114 KINDRED--Kidney General STREET Information Hospital Network for (1114196961) Disease Research and Education ------------------------------------------------------------------------ Tufts Medical 800 BOSTON MA 02111 The Prevalence, Center (.) WASHINGTON Morphology, ST Clinical Course and Management of Patients with Anderson- Fabry Disease Identified Among a Large Adult Population ------------------------------------------------------------------------ University Of 619 SOUTH BIRMING AL 35233 Teriflunomide as Alabama 19TH HAM a disease Hospital (.) STREET modifying anti- inflammatory therapy for a severe animal model of chronic inflammatory demyelinating polyneuropathy ------------------------------------------------------------------------ Langley Porter 405 SAN CA 94143 A Phase I Study Psychiatric PARNASUS FRANCI of Cabazitaxel, Hosptial SCO Mitoxanthrone, (1417115031) and Prednisone (CAMP) for Patients with Metastatic Castration- Resistant Prostate Cancer ------------------------------------------------------------------------ Brigham And 75 FRANCIS BOSTON MA 02115 Post-partum MRI Womens STREET Changes in Hospital Women with (1013935550) Multiple Sclerosis. ------------------------------------------------------------------------ University Of 1959 NE SEATTLE WA 98195 Establishing an Washington PACIFIC ST in-vitro Model Med Ctr (.) of Fabry Podocytopathy ------------------------------------------------------------------------ UCI Medical 101 CITY ORANGE CA 92868 Investigating Center (.) DRIVE Pompe SOUTH Prevalence in NEuromuscular Medicine Academic Practices (IPANEMA Study) ------------------------------------------------------------------------ UCI Medical 101 CITY ORANGE CA 92868 Safety and Center (.) DRIVE Effectiveness SOUTH of Resistance exercise training in late onset Pompe disease patients--a pilot study ------------------------------------------------------------------------ Emory 1364 ATLANTA GA 30302 Do the Benefits University CLIFTON Outweigh the Hospital (.) ROAD Risks? Assessing Patients' Perceptions of Newborn Screening for Lysosomal Storage Diseases ------------------------------------------------------------------------ USC Norris 1441 LOS CA 90033 Detection of Cancer EASTLAKE ANGELE early end-organ Hospital AVE S damage by (1104096577) endothelial dysfunction with reactive hyperemia- digital peripheral arterial tonometry in patients with Fabry Disease ------------------------------------------------------------------------ Emory 1364 ATLANTA GA 30302 A Prospective, University CLIFTON Multicenter Hospital (.) ROAD Study Of Fabry Disease Clinical and Biochemical Findings in Young Pediatric Patients (The MOPPET Study) ------------------------------------------------------------------------ University Of 1959 NE SEATTLE WA 98195 Establishing an Washington PACIFIC ST in-vitro Model Med Ctr (.) of Fabry Podocytopathy ------------------------------------------------------------------------ Cleveland 9500 EUCLID CLEVELA OH 44195 A Randomized, Clinic AVENUE ND Controlled, Hospital open-labeled (1013392125) Clinical Trial of Thymoglobulin? Induction and Extended Delay of Calcineurin Inhibitor Therapy for Renal Protection after Liver Transplantation A Multi-Center Study ------------------------------------------------------------------------ Cleveland 9500 EUCLID CLEVELA OH 44195 A Randomized, Clinic AVENUE ND Controlled, Hospital open-labeled (1013392125) Clinical Trial of Thymoglobulin? Induction and Extended Delay of Calcineurin Inhibitor Therapy for Renal Protection after Liver Transplantation A Multi-Center Study ------------------------------------------------------------------------ Cleveland 9500 EUCLID CLEVELA OH 44195 A Randomized, Clinic AVENUE ND Controlled, Hospital open-labeled (1013392125) Clinical Trial of Thymoglobulin? Induction and Extended Delay of Calcineurin Inhibitor Therapy for Renal Protection after Liver Transplantation A Multi-Center Study ------------------------------------------------------------------------ Cleveland 9500 EUCLID CLEVELA OH 44195 A Randomized, Clinic AVENUE ND Controlled, Hospital open-labeled (1013392125) Clinical Trial of Thymoglobulin? Induction and Extended Delay of Calcineurin Inhibitor Therapy for Renal Protection after Liver Transplantation A Multi-Center Study ------------------------------------------------------------------------ OHSU Hospital 3181 SAM PORTLAN OR 97239 A Phase I/II and Clinics JACKSON D Trial of (1053454645) PARK ROAD Concurrent Chemohormonal Therapy Using Enzalutamide (MDV-3100) and Cabazitaxel in Patients with Metastatic Castration Resistant Prostate Cancer ------------------------------------------------------------------------ OHSU Hospital 3181 SAM PORTLAN OR 97239 A Phase I/II and Clinics JACKSON D Trial of (1053454645) PARK ROAD Concurrent Chemohormonal Therapy Using Enzalutamide (MDV-3100) and Cabazitaxel in Patients with Metastatic Castration Resistant Prostate Cancer ------------------------------------------------------------------------ OHSU Hospital 3181 SAM PORTLAN OR 97239 A Phase I/II and Clinics JACKSON D Trial of (1053454645) PARK ROAD Concurrent Chemohormonal Therapy Using Enzalutamide (MDV-3100) and Cabazitaxel in Patients with Metastatic Castration Resistant Prostate Cancer ------------------------------------------------------------------------ Mount Sinai FIRST NEW NY 10003 Gaucher Beth Israel AVENUE AT YORK Generation--Cog (1003052200) 16 STREET nition, Motor Control, Imaging and Pathologic Biomarkers in GBA1 Mutation Carriers ------------------------------------------------------------------------ University Of 1959 NE SEATTLE WA 98195 Fluctuation Washington PACIFIC ST Reduction with Med Ctr (.) Insulin and GLP--1 Added Together (FLAT- SUGAR) ------------------------------------------------------------------------ University Of 1959 NE SEATTLE WA 98195 Fluctuation Washington PACIFIC ST Reduction with Med Ctr (.) Insulin and GLP- 1 Added Together (FLAT- SUGAR) ------------------------------------------------------------------------ Brigham And 75 FRANCIS BOSTON MA 02115 miRNA profiling Womens STREET in Hospital Teriflunomide (1013935550) (Aubagio) treated patients ------------------------------------------------------------------------ Massachusetts FRUIT BOSTON MA 02114 Factors General STREET influencing Hospital patient (1114196961) preferences for oral versus intravenous (IV) enzyme replacement medication. ------------------------------------------------------------------------ University Of 1959 NE SEATTLE WA 98195 Localization of Washington PACIFIC ST Globotriaosylce Med Ctr (.) ramide (GL3) Inclusions in Fabry Podocytes ------------------------------------------------------------------------ Emory 1364 ATLANTA GA 30302 Online Social University CLIFTON Networking Use Hospital (.) ROAD Among Individuals Affected with Lysosomal Storage Diseases: ``Friend'' or Foe? ------------------------------------------------------------------------ University Of 619 SOUTH BIRMING AL 35233 Comparative Alabama 19TH HAM Proteomics and Hospital (.) STREET Lipidomics of Exosomes Isolated from Serum and Urine in Fabry Disease ------------------------------------------------------------------------ Emory 1364 ATLANTA GA 30302 Glargine U300 University CLIFTON Hospital Trial: Hospital (.) ROAD A Randomized Controlled Trial Comparing Glargine U300 and Glargine U100 for the Inpatient and Post-Hospital Discharge Management of Medicine and Surgery Patients with Type 2 Diabetes ------------------------------------------------------------------------ UC Davis 2315 SACRAME CA 95817 A Selective Medical STOCKTON NTO Frontline Center (.) BLVD Jevtana Therapeutic Pathway for Castration- Resistant Prostate Cancer with Integrated Biomarkers ------------------------------------------------------------------------ Cleveland 9500 EUCLID CLEVELA OH 44195 A Study of Clinic AVENUE ND Hematopoietic Hospital Stem Cell (1013392125) Supermobilizati on in Patients with Lymphoma ------------------------------------------------------------------------ UH Cleveland 11100 CLEVELA OH 44106 Epidemiology of Medical EUCLID ND Diabetes Center AVENUE Interventions (1013954395) and Complications ------------------------------------------------------------------------ UH Cleveland 11100 CLEVELA OH 44106 Epidemiology of Medical EUCLID ND Diabetes Center AVENUE Interventions (1013954395) and Complications ------------------------------------------------------------------------ UH Cleveland 11100 CLEVELA OH 44106 Epidemiology of Medical EUCLID ND Diabetes Center AVENUE Interventions (1013954395) and Complications ------------------------------------------------------------------------ Univ Of ONE COLUMBI MO 65212 Epidemiology of Missouri HOSPITAL A Diabetes Health Care DRIVE Interventions (1033499256) and Complications ------------------------------------------------------------------------ Univ Of ONE COLUMBI MO 65212 Epidemiology of Missouri HOSPITAL A Diabetes Health Care DRIVE Interventions (1033499256) and Complications ------------------------------------------------------------------------ Yale-New Haven 20 YORK NEW CT 06504 Epidemiology of Hospital STREET HAVEN Diabetes (1003142225) Interventions and Complications ------------------------------------------------------------------------ University Of 22 SOUTH BATLIMO MD 21201 Epidemiology of Maryland Med GREENE RE Diabetes Sys STREET Interventions (1023304888) and Complications ------------------------------------------------------------------------ University Of 22 SOUTH BATLIMO MD 21201 Epidemiology of Maryland Med GREENE RE Diabetes Sys STREET Interventions (1023304888) and Complications ------------------------------------------------------------------------ University Of 22 SOUTH BATLIMO MD 21201 Epidemiology of Maryland Med GREENE RE Diabetes Sys STREET Interventions (1023304888) and Complications ------------------------------------------------------------------------ UT MD Anderson 1515 HOUSTON TX 77030 A Dynamic Cancer Center HOLCOMBE Allocation (1053755272) BLVD Modular Sequential Trial of Approved and Promising Therapies in Men with Metastatic Castration- Resistant Prostate Cancer ------------------------------------------------------------------------ OHSU Hospital 3181 SAM PORTLAN OR 97239 A Phase I/II And Clinics JACKSON D Trial of (1033650353) PARK ROAD Concurrent Chemohormonal Therapy Using Enzalutamide (MDV-3100) and Cabazitaxel in Patients with Metastatic Castration ------------------------------------------------------------------------ UT MD Anderson 1515 HOUSTON TX 77030 A Dynamic Cancer Center HOLCOMBE Allocation (1053755272) BLVD Modular Sequential Trial of Approved And Promising Therapies in Men with Metastatic Castration- Resistant Prostate Cancer ------------------------------------------------------------------------ Charleston 501 MORRIS CHARLES WV 25326 A Phase II Trial Area Medical STREET TON of GM-CSF Center Inc. Protein plus (1124248752) Ipilimumab in Patients with Advanced Melanoma (ECOG 1608) ------------------------------------------------------------------------ UT MD Anderson 1515 HOUSTON TX 77030 A Dynamic Cancer Center HOLCOMBE Allocation (1053755272) BLVD Modular Sequential Trial of Approved And Promising Therapies in Men with Metastatic Castration- Resistant Prostate Cancer ------------------------------------------------------------------------ OHSU Hospital 3181 SAM PORTLAN OR 97239 A Phase I/II And Clinics JACKSON D Trial of (1033650353) PARK ROAD Concurrent Chemohormonal Therapy Using Enzalutamide (MDV-3100) and Cabazitaxel in Patients with Metastatic Castration- Resistant Prostate Cancer ------------------------------------------------------------------------ Univ Of ONE COLUMBI MO 65212 Epidemiology of Missouri HOSPITAL A Diabetes Health Care DRIVE Interventions (1033499256) and Complications ------------------------------------------------------------------------ Yale-New Haven 20 YORK NEW CT 06504 Epidemiology of Hospital STREET HAVEN Diabetes (1003142225) Interventions and Complications ------------------------------------------------------------------------ UH Cleveland 11100 CLEVELA OH 44106 Epidemiology of Medical EUCLID ND Diabetes Center AVENUE Interventions (1013954395) and Complications ------------------------------------------------------------------------ University Of 22 SOUTH BATLIMO MD 21201 Epidemiology of Maryland Med GREENE RE Diabetes Sys STREET Interventions (1023304888) and Complications ------------------------------------------------------------------------ OHSU Hospital 3181 SAM PORTLAN OR 97239 A Phase I/II And Clinics JACKSON D Trial of (1033650353) PARK ROAD Concurrent Chemohormonal Therapy Using Enzalutamide (MDV-3100) and Cabazitaxel in Patients with Metastatic Castration- Resistant Prostate Cancer ------------------------------------------------------------------------ Texas 6621 FANNIN HOUSTON TX 77030 Phase II Study Childrens of Clofarabine Hospital in Patients (1013283159) with Recurrent or Refractory Langerhans Cell Histiocytosis ------------------------------------------------------------------------ Massachusetts FRUIT BOSTON MA 02114 Phase II Study General STREET of Clofarabine Hospital in Patients (1114196961) with Recurrent or Refractory Langerhans Cell Histiocytosis ------------------------------------------------------------------------ Texas 6621 FANNIN HOUSTON TX 77030 Phase II Study Childrens of Clofarabine Hospital in Patients (1013283159) with Recurrent or Refractory Langerhans Cell Histiocytosis ------------------------------------------------------------------------ Childrens 4650 SUNSET LOS CA 90027 Phase II Study Hospital Los BOULEVARD ANGELE of Clofarabine Angeles S in Patients (1003102781) with Recurrent or Refractory Langerhans Cell Histiocytosis ------------------------------------------------------------------------ UT MD Anderson 1515 HOUSTON TX 77030 A Dynamic Cancer Center HOLCOMBE Allocation (1053755272) BLVD Modular Sequential Trial of Approved and Promising Therapies in Men with Metastatic Castration- Resistant Prostate Cancer ------------------------------------------------------------------------ OHSU Hospital 3181 SAM PORTLAN OR 97239 A Phase I/II And Clinics JACKSON D Trial of (1033650353) PARK ROAD Concurrent Chemohormonal Therapy Using Enzalutamide (MDV-3100) and Cabazitaxel in Patients with Metastatic Castration- Resistant Prostate Cancer ------------------------------------------------------------------------ UT MD Anderson 1515 HOUSTON TX 77030 A Dynamic Cancer Center HOLCOMBE Allocation (1053755272) BLVD Modular Sequential Trial of Approved and Promising Therapies in Men with Metastatic Castration- Resistant Prostate Cancer ------------------------------------------------------------------------ Texas 6621 FANNIN HOUSTON TX 77030 Phase II Study Childrens of Clofarabine Hospital in Patients (1013283159) with Recurrent or Refractory Langerhans Cell Histiocytosis ------------------------------------------------------------------------ OHSU Hospital 3181 SAM PORTLAN OR 97239 A Phase I/II And Clinics JACKSON D Trial of (1033650353) PARK ROAD Concurrent Chemohormonal Therapy Using Enzalutamide (MDV-3100) and Cabazitaxel in Patients with Metastatic Castration- Resistant Prostate Cancer ------------------------------------------------------------------------ UT MD Anderson 1515 HOUSTON TX 77030 IST-1L- Cancer Center HOLCOMBE Smoldering (1053755272) BLVD myeloma-PT-IV ------------------------------------------------------------------------ UT MD Anderson 1515 HOUSTON TX 77030 SAR650984--Anti- Cancer Center HOLCOMBE CD38 naked mAb-- (1053755272) BLVD isatuximab ------------------------------------------------------------------------ UT MD Anderson 1515 HOUSTON TX 77030 IST-1L- Cancer Center HOLCOMBE Smoldering (1053755272) BLVD myeloma-PT-IV ------------------------------------------------------------------------ UT MD Anderson 1515 HOUSTON TX 77030 IST-1L- Cancer Center HOLCOMBE Smoldering (1053755272) BLVD myeloma-PT-IV ------------------------------------------------------------------------ Rochester 1425 ROCHEST NY 14617 A Study General PORTLAND ER Evaluating Hospital AVENUE Acute Otitis (1023105376) Media and Nasopharyngeal Colonization Caused by Streptococcus pneumoniae in Healthy Children ------------------------------------------------------------------------ KFH-Hawaii 3288 HONOLUL HI 96819 Efficacy of (1306928254) MOANALUA U Flublok study ROAD ------------------------------------------------------------------------ KFH-Hawaii 3288 HONOLUL HI 96819 Vaccine (1306928254) MOANALUA U effectiveness ROAD of Flublok 18- 64 ------------------------------------------------------------------------ University of 855 WEST CHARLOT VA 22908 IRB-HSR#14386 Virginia MAIN TESVIL Medical Cente STREET L (.) ------------------------------------------------------------------------ Tufts Medical 800 BOSTON MA 02111 The Prevalence, Center WASHINGTON Morphology, (1114162013) ST Clinical Course and Management of Patients with Anderson- Fabry Disease Identified Among a Large Adult Population ------------------------------------------------------------------------ Massachusetts FRUIT BOSTON MA 02114 Characterization General STREET and analysis of Hospital pathophysiology (1114196961) of the gastrointestina l complications of Fabry disease. ------------------------------------------------------------------------ Cleveland 9500 EUCLID CLEVELA OH 44195 Biomarkers of Clinic AVENUE ND Disease Hospital Heterogeneity (1013392125) in Multiple Sclerosis: Phase II ------------------------------------------------------------------------ UCI Medical 101 THE SOUTH CA 92868 Investigating Center (.) CITY DRIVE ORANGE Pompe Prevalence in NEuromuscular Medicine Academic Practices (IPANEMA Study) ------------------------------------------------------------------------ Cleveland 9500 EUCLID CLEVELA OH 44195 A Randomized, Clinic AVENUE ND Controlled, Hospital open-labeled (1013392125) Clinical Trial of Thymoglobulin? Induction and Extended Delay of Calcineurin Inhibitor Therapy for Renal Failure ------------------------------------------------------------------------ Cleveland 9500 EUCLID CLEVELA OH 44195 A Randomized, Clinic AVENUE ND Controlled, Hospital open-labeled (1013392125) Clinical Trial of Thymoglobulin? Induction and Extended Delay of Calcineurin Inhibitor Therapy for Renal Failure ------------------------------------------------------------------------ Cleveland 9500 EUCLID CLEVELA OH 44195 A Randomized, Clinic AVENUE ND Controlled, Hospital open-labeled (1013392125) Clinical Trial of Thymoglobulin? Induction and Extended Delay of Calcineurin Inhibitor Therapy for Renal Failure ------------------------------------------------------------------------ OHSU Hospital 3181 SAM PORTLAN OR 97239 A Phase I/II And Clinics JACKSON D Trial of (1033650353) PARK ROAD Concurrent Chemohormonal Therapy Using Enzalutamide (MDV-3100) and Cabazitaxel in Patients with Metastatic Castration- Resistant Prostate Cancer ------------------------------------------------------------------------ Mount Sinai 1ST AVENUE@ NEW NY 10003 Gaucher Beth Israel 16TH YORK Generation--Cog (1003052200) STREET nition, Motor Control, Imaging and Pathologic Biomarkers in GBA1 Mutation Carriers ------------------------------------------------------------------------ Mount Sinai 1ST AVENUE@ NEW NY 10003 Gaucher Beth Israel 16TH YORK Generation--Cog (1003052200) STREET nition, Motor Control, Imaging and Pathologic Biomarkers in GBA1 Mutation Carriers ------------------------------------------------------------------------ Emory 1364 ATLANTA GA 30302 Newborn University CLIFTON Screening XLSD Hospital (.) ROAD Pilot Study ------------------------------------------------------------------------ University of 619 SOUTH BIRMING AL 35233 Comparative Alabama 19TH HAM Proteomics and Hospital (.) STREET Lipidomics of Exosomes Isolated from Serum and Urine in Fabry Disease ------------------------------------------------------------------------ UT MD Anderson 1515 HOUSTON TX 77030 Interest of CT Cancer Center HOLCOMBE Morphological (1053755272) BLVD Evaluation in Patients with Metastatic Colorectal Cancer Treated with ZIV- Aflibercept ------------------------------------------------------------------------ Brigham And 75 FRANCIS BOSTON MA 02115 New England Womens STREET Multiple Hospital Sclerosis (1013935550) Pregnancy Registry (PREG- MS) ------------------------------------------------------------------------ Brigham and 75 FRANCIS BOSTON MA 02115 New England Womens STREET Multiple Hospital Sclerosis (1013935550) Pregnancy Registry (PREG- MS) ------------------------------------------------------------------------ Brigham And 75 FRANCIS BOSTON MA 02115 New England Womens STREET Multiple Hospital Sclerosis (1013935550) Pregnancy Registry (PREG- MS) ------------------------------------------------------------------------ Univ Of Mi 2301 ANN MI 48105 Regulatory B Hospitals & COMMONWEAL ARBOR Lymphocytes as Hlth Ctrs TH BLVD Central (1043488760) Mediators of the Therapeutic Effects of Teriflunomide in MS ------------------------------------------------------------------------ Univ Of Mi 2301 ANN MI 48105 Regulatory B Hospitals & COMMONWEAL ARBOR Lymphocytes as Hlth Ctrs TH BLVD Central (1043488760) Mediators of the Therapeutic Effects of Teriflunomide in MS ------------------------------------------------------------------------ OHSU Hospital 3181 SAM PORTLAN OR 97239 Bright tongue and Clinics JACKSON D sign in Pompe (1033650353) PARK ROAD disease: sensitivity and specificity ------------------------------------------------------------------------ OHSU Hospital 3181 SAM PORTLAN OR 97239 Bright tongue And Clinics JACKSON D sign in Pompe (1033650353) PARK ROAD disease: sensitivity and specificity ------------------------------------------------------------------------ Brigham And 75 FRANCIS BOSTON MA 02115 miRNA profiling Womens STREET in Hospital Teriflunomide (1013935550) (Aubagio) treated patients ------------------------------------------------------------------------ Massachusetts FRUIT BOSTON MA 02114 Enzyme General STREET Replacement Hospital Therapy and (1114196961) Podocyte Function ------------------------------------------------------------------------ Massachusetts FRUIT BOSTON MA 02114 KINDRED--Kidney General STREET Information Hospital Network for (1114196961) Disease Research and Education ------------------------------------------------------------------------ Emory 1364 ATLANTA GA 30302 ThinkGenetic University CLIFTON LSD: A project Hospital (.) ROAD to identify educational gaps in the informational needs of individuals with Pompe, Fabry, Gaucher, Mucopolysacchar ide Diseases ------------------------------------------------------------------------ Cedars-Sinai 8700 LOS CA 90048 A Pilot Medical BEVERLY ANGELE Randomized Center (.) BLVD. S Study to Assess the Effect and Safety Profile of Thymoglobulin? in Primary Cardiac Transplant Recipients: A 12-month, single center study ------------------------------------------------------------------------ Massachusetts FRUIT BOSTON MA 02114 Characterization General STREET and analysis of Hospital pathophysiology (1114196961) of the gastrointestina l complications of Fabry disease. ------------------------------------------------------------------------ University Of 619 SOUTH BIRMING AL 35233 Teriflunomide as Alabama 19TH HAM a disease Hospital (.) STREET modifying anti- inflammatory therapy for a severe animal model of chronic inflammatory demyelinating polyneuropathy ------------------------------------------------------------------------ USC Norris 1441 LOS CA 90033 Assessing the Cancer EASTLAKE ANGELE induction of Hospital AVE S long-term (1104096577) immune regulation following treatment with Lemtrada? (Alemtuzumab). ------------------------------------------------------------------------ USC Norris 1441 LOS CA 90033 Assessing the Cancer EASTLAKE ANGELE induction of Hospital AVE S long-term (1104096577) immune regulation following treatment with Lemtrada? (Alemtuzumab). ------------------------------------------------------------------------ Emory 1364 ATLANTA GA 30302 Functional University CLIFTON Resolution of Hospital (.) ROAD Multi-loci Pathogenic Variants and VUSs in Pompe Disease ------------------------------------------------------------------------ Prepared Statement of Giovanni Caforio, M.D., Chairman of the Board and Chief Executive Officer, Bristol-Myers Squibb Company Chairman Grassley, Ranking Member Wyden, and members of the committee, thank you for the opportunity to be here today on behalf of the 24,000 employees at Bristol-Myers Squibb, who are working every day to improve the lives of patients with serious diseases. I look forward to working together to align incentives to ensure all Americans have access to the medicines they need. I am a physician who joined the biopharmaceutical industry 30 years ago because of the impact companies like Bristol-Myers Squibb--and the others represented here today--have on patients with serious diseases. We should all be proud that American companies lead our industry. Bristol-Myers Squibb researchers have contributed to the development of medicines that have reduced mortality from cardiovascular disease, helped transform HIV/AIDS into a chronic disease, and are now making significant progress in the treatment of cancer. Just 10 years ago, the idea of harnessing the immune system to treat cancer was viewed with great skepticism. But Bristol-Myers Squibb researchers saw the promise of the approach and ignited an era of scientific innovation that has changed survival expectations in multiple tumor types. Prior to the availability of Immuno-Oncology treatments, only 25 percent of patients diagnosed with metastatic melanoma survived 1 year. Today, thanks to Immuno-Oncology therapies, this has increased to 74 percent. The potential of this approach has also been seen in lung cancer, kidney cancer, and many other difficult-to-treat tumors. Patients with these diseases now have a chance for quality, long-term survival. But not all patients respond to current immunotherapies, so we must do more. We recently opened a new discovery facility dedicated to investigating Immuno- Oncology resistance, and we continuously seek external innovation to augment our pipeline across multiple therapeutic areas. In this context, we recently announced our plan to acquire Celgene, a natural next step for our company. Our goal is to bring together the drive and dedication of two science-driven organizations to do even more for patients. As a physician, I recognize that medicines are only helpful if patients and health-care systems can afford them. We share the committee's concern with escalating health-care costs and believe that our responsibility to patients extends to ensuring they can access and afford our medicines. The average net pricing across our U.S. portfolio of medicines increased by 5 percent or less per year during the last 5 years. In 2018, it did not increase and we anticipate the same in 2019. Despite this fact, we recognize that patients' out-of-pocket costs continue to increase. We believe it is possible to work together to realign incentives to ensure patients can afford medicines without stifling scientific innovation. So what are the solutions? We are supportive of the proposed rule aimed at reforming the rebate system with a focus on what is best for patients. We need to ensure more generics are available whenever permissible under our system, and applaud Congress and the administration's success with speeding the approval of generics. We support value-based purchasing arrangements that tie payments to value. These models can reduce costs, improve access and adherence, and contribute to better outcomes. We applaud efforts by Health and Human Services and the Committee to remove regulatory barriers and facilitate greater use of these arrangements. We do not believe the U.S. should adopt policies that stifle innovation in other countries, which could reduce a patient's access to new medicines. Outside of the U.S., reimbursement of new medicines can often take more than two years. Our Opdivo and Yervoy regimen was first approved in September 2015 to treat metastatic melanoma in the U.S. Today, six of the 16 countries included in the International Price Index proposal do not provide access to this combination, which is now considered the standard of care for this cancer. This exemplifies why Bristol-Myers Squibb does not support HHS's proposed International Price Index Model for Medicare Part B drugs. I would like to leave you with a few thoughts. We are witnessing a historic era in biomedical innovation. But we must ensure patients have affordable access to these innovations. We recognize the need for change, and we are committed to working with Congress to ensure every patient can benefit from today's medical innovations. American research-based companies are leading the next wave of biomedical innovation to help patients whose diseases cannot be adequately treated with today's medicines. We should work to ensure policies that support and reward these investments. On behalf of my colleagues at Bristol-Myers Squibb, and the patients we serve, my sincere thanks for your time and attention today. I look forward to working together to implement real change that broadens access to innovative medicines for patients. ______ Questions Submitted for the Record to Giovanni Caforio, M.D. Questions Submitted by Hon. Chuck Grassley Question. At the hearing, you testified that Bristol-Myers Squibb does not withhold samples from generic manufacturers in order to block generic versions of your drug from entering the market. You also expressed your support for the ``Creating and Restoring Equal Access to Equivalent Samples Act,'' also known as the CREATES Act. As you know, the FDA has a list on its website which identifies reference listed drug (RLD) access inquiries where brand manufacturers may have prevented generic companies from obtaining samples of products necessary to support FDA approval. Celgene is on this FDA list. According to your testimony, Bristol-Myers Squibb is in the process of acquiring Celgene. Are you aware that Celgene is on the FDA list and that Celgene had multiple access inquiries? Answer. Yes. Question. Will you ensure that Bristol-Myers Squibb/Celgene will not block access to samples once the Celgene acquisition is final? Answer. As Dr. Caforio testified at the hearing, BMS does not withhold samples from generic manufacturers in order to block generic versions of the drug from entering the market. BMS believes it is important to ensure generics are made available whenever that is permissible under our system, and supports the administration's focus on increasing the approval of generics. As part of that system, it is important that generic companies perform the needed testing to ensure product quality and patient safety. BMS cannot comment on Celgene's practices in this area, but once the transaction closes, BMS's practices with regard to generic samples will govern the combined portfolio. Question. The Department of Health and Human Services' proposed rule, ``Fraud and Abuse; Removal of Safe Harbor Protection for Rebates Involving Prescription Pharmaceuticals and Creation of New Safe Harbor Protection for Certain Point-of-Sale Reductions in Price on Prescription Pharmaceuticals and Certain Pharmacy Benefit Manager Service Fees,'' envisions that drug manufacturers will offer up-front discounts rather than the back-end rebates that are now commonly provided. Some observers argue that a 1996 court case called into question whether manufacturers could offer up-front discounts, resulting in today's rebate-based system. I've heard differing opinions as to whether the issues related to the initial court case are still relevant. If the HHS proposed rule is finalized, can you assure the committee that your company will offer up-front discounts? If not, why? Answer. BMS supports the HHS proposed rule to eliminate safe harbor protection for back-end rebates under Medicare Part D and the rule's objective to ensure that patients benefit from price reductions that BMS provides on its drugs. As the proposed rule notes, there is uncertainty as to the strategic behavior changes that will occur if the rule is enacted, and therefore uncertainty as to precise mechanisms that will be available to meet the objectives of the rule. However, there is some risk that manufacturers would have to defend themselves against antitrust litigation if they were to offer up-front discounts instead of rebates if the proposed rule were finalized. In particular, there may be risk of claims being crafted under the Robinson-Patman Act, 15 U.S.C. Sec. 13. Any such claims would have to meet significant substantive requirements and be subject to important statutory defenses. Nonetheless, even if meritless, Robinson-Patman claims can be expensive and time consuming for manufacturers to defend against. In light of the potential for antitrust litigation, BMS recommends that the committee consider how best to address this risk as it considers the HHS proposal. Congress, could, for example, enact legislation that immunizes from liability under the Robinson-Patman Act drug manufacturers who offer up-front discounting under Medicare Part D in accordance with the fraud and abuse safe harbor created by the HHS rule. Question. Please describe how you expect your company to respond to the HHS proposed rule to eliminate safe harbor protection for back-end rebates in Medicare Part D that is referenced above if it is finalized. Assuming you are confident that antitrust laws do not prevent your company from offering up-front discounts, specifically, do you envision that your company lowers the list price of a drug to the current after- rebate net price, offer discounts equal to the current rebate amount, or a combination of both? Answer. BMS supports the HHS proposed rule to eliminate safe harbor protection for back-end rebates in Medicare Part D, and we believe it would lead to lower out-of-pocket costs. This question rightly supposes that the goals of the proposed rule could be achieved through lower list prices, negotiated discounts at the point-of-sale, or some combination of these two approaches. While it is unclear how Part D plans and PBMs will react to the proposed rule, at this time, BMS envisions that we would offer point-of-sale discounts to Part D plans equivalent on average to the current contracted rebate amount and will continue to assess the possibility of lowering list price on a product- by-product basis. Our ability to lower list prices, however, is constrained by the fact that the HHS proposed rule does not apply to the commercial insurance market, where we anticipate back-end rebates to continue for the foreseeable future. Please also see the answer to the previous question. Question. To what extent are the back-end rebates your company currently offers contingent on the amount of market share realized for your drugs as a result of Part D plan formulary placement and other techniques? Answer. The back-end rebates BMS currently offers pursuant to its Medicare Part D agreements are not contingent on the amount of market share realized for any of BMS's drugs as a result of Part D plan formulary placement or any other performance requirement. Question. Please provide a breakdown of percentage of sales that go to each payer (including Medicare, Medicaid, private pay, other) and a similar percentage by volume of the total number of each drug compared to total volume. Please provide this data for the most recent year available. Answer. This information is not available publicly and is competitively sensitive. Question. Do your companies hire consultants or lobbyists to promote products at State Medicaid Pharmacy and Therapeutics Committees? To whom do you disclose advocacy activities surrounding State Medicaid programs, if at all? Answer. BMS does not hire consultants or lobbyists to promote its products at State Medicaid P&T Committees. BMS complies with the applicable lobbying laws across all 50 States, Puerto Rico, and the District of Columbia. Many States require engagement with its Medicaid officials to be reported. We disclose required lobbying activities to each State in accordance with the individual State lobbying disclosure and ethics laws. Question. Please describe how the costs of patient assistance programs are accounted for within your company's financial statements. Please also describe the types of market information, such as prescribing and use patterns that your company collects from different types of patient assistance programs and patient hub services. Answer. For purposes of responding to this request, BMS interprets ``patient assistance programs'' and ``patient hub services'' as BMS programs or services supporting education, access and/or treatment adherence for eligible patients who are prescribed a BMS medicine. Costs associated with these programs are accounted for in our financial statements as marketing, selling and administrative expenses or gross- to-net sales adjustments, depending on the type of assistance offered. Data captured through the administration of patient support programs allows our program administrators to validate information provided directly from patients and providers in support of the specific program(s) for which assistance is being requested. This data capture includes, but may not be limited to: (1) information that supports determination of patient eligibility; (2) validation of licensed provider/prescriber; (3) prescription related information necessary to execute patient assistance available through program(s) (i.e., dosage and units being prescribed/dispensed); and, (4) insurance information. Question. Please provide a list of all contributions since January 1, 2014, that your company has made to any tax exempt organizations working on issues related to drugs within your product lines, including but not limited to patient groups, disease awareness groups, medical or professional societies, universities or hospitals, industry associations or leagues. For each contribution, please provide the name of the organization that received the donation, the date the donation was made, the amount of the donation, and a description of the purpose of the contribution (i.e., was the contribution for the general fund, a specific purpose to a specific program, or continuing medical education). Please also note whether the contribution was unrestricted or restricted; if it was restricted, please explain all restrictions. Finally, if your company maintains a foundation or other separate charitable arm, please provide the name of all such entities, and list all donations made from that entity or entities. Answer. BMS refers the committee to the Corporate Giving page on the BMS website (https://www.bms.com/about-us/responsibility/corporate- giving.html). This page includes comprehensive information about BMS' Corporate Giving policies and practices. It also includes comprehensive lists of IME Grants, Charitable Donations and Corporate Giving for calendar years 2016, 2017 and 2018. These grants are made for a variety of appropriate purposes, not limited to issues related to drugs within the BMS product line. BMS supports the BMS Patient Assistance Foundation (BMSPAF), a non- profit organization that helps patients in the United States who need temporary help obtaining various BMS medications. In 2018, BMS donated over $1 billion worth of BMS medicines to the BMSPAF, and the BMSPAF provided free medicine to more than 75,000 patients. BMS also supports the Bristol-Myers Squibb Foundation, a non-profit organization that promotes health equity and seeks to improve the health outcomes of populations disproportionately affected by serious diseases by strengthening health-care worker capacity, integrating medical care and community based support services, and mobilizing communities to fight against disease. BMS views the activities of the BMS Foundation as outside the scope of this question. Question. Pay for delay agreements cost consumers and taxpayers billions in higher drug costs every year. The FTC has gone after drug companies that enter into these settlements where the brand pays the generic company to keep its lower cost alternative off the market. I'm the lead Republican sponsor of S. 64, the ``Preserve Access to Affordable Generics and Biosimilars Act,'' which would help put an end to these deals. Do you agree that these pay-off agreements keep drug costs high for patients because they delay competition? Answer. BMS agrees that patent settlement agreements that have substantial payments going from innovators to generics, and are solely intended to delay competition, are anticompetitive. Question. Has your company ever entered into these kinds of settlements with a generic company? Answer. BMS has not entered into patent settlements that have substantial payments going from innovator to generics and are solely intended to delay competition. Question. Do you support the pay for delay bill? Answer. In general, the ability to settle patent litigation, like any litigation, reflects a balancing of considerations by the involved parties and often leads to earlier generic entry than patent expiration. The current system provides the government with the ability to monitor and review these settlements, and has worked well. With regard to S. 64, BMS supports the goals of the legislation but has objections to the legislation as currently drafted. For example, the legislation should be revised: (1) only to apply prospectively and not retroactively to agreements already entered into; (2) eliminate the presumption that all settlements are presumptively anticompetitive; (3) eliminate restrictions on the arguments companies would be permitted to advance to defend agreements; and (4) include ``exclusions'' for certain types of agreements, such as those containing exclusive licenses, to name a few. BMS would be happy to follow up and provide further details to the committee. rebate traps/walls Question. I'm increasingly concerned about the effect of so-called ``rebate traps'' or ``rebate walls'' on patients' access to quality, lower cost medicine. I understand there is ongoing litigation challenging these practices as anti-competitive. Does your company engage in the bundling of rebates over multiple products? If so, why? And what benefit does the consumer gain from that? Answer. BMS does not have any Medicare Part D or any other payer contracts with bundling of rebates. Question. Does your company view these practices as anticompetitive or harmful to patients' access to quality, lower cost medicine? Answer. BMS believes that clinical treatment decisions should be made by physicians in consultation with patients. As noted, BMS does not have bundled payer agreements and without insight to the specific terms of other manufacturers' bundling agreements, it is difficult to assess the impact on patient access and healthcare costs. BMS does not support agreements that create barriers to patients' access to quality, lower cost medicines. Question. If a policy were adopted to eliminate rebates, or to require that rebate savings be passed on to the consumer, would that in and of itself solve the issue of rebate ``traps'' and ``walls''? And would consumers benefit from such a policy? Answer. BMS believes that requiring PBMs and payers to pass manufacturer rebates on to patients has the potential to lower patient out-of-pocket costs, and therefore benefit consumers. However, it is unclear how payers will adjust their benefit plan designs in response to this change and whether it would completely solve the issue of rebate ``traps'' and ``walls.'' It is possible, for example, that in response to such changes, PBM and payer business models might evolve, and thus we recommend implementing safeguards to protect consumers' access to medicines. drug pricing Question. When setting the list price of a drug, does your company consider regulatory costs or compliance? If so, how specifically do those factors affect the list price of a drug? Please provide at least one specific example, if applicable, from your current product portfolio. Answer. BMS does not consider these costs in setting list price. Question. When setting the list price of a drug, does your company consider the risk of liability or litigation? If so, how specifically do those factors affect the list price of a drug? Please provide at least one specific example, if applicable, from your current product portfolio. Answer. BMS does not consider the risk of liability or litigation in setting list price. ______ Questions Submitted by Hon. Pat Roberts Question. What role do you see Value Based Arrangements (VBAs) playing in the effort to reduce prescription drug costs? What potential do these arrangements have to find the ``sweet spot'' between controlling costs to patients and encouraging innovation of new drugs? Answer. Manufacturers and payers have been participating in Value Based Agreements (VBAs) with increasing frequency. These agreements can potentially reduce overall health-care costs by reducing costs for medicines, and importantly, improving outcomes for patients and reducing overall health-care costs. Although there are many types of VBAs, and the goals and impact of these arrangements differ by specific medicines and therapeutic areas, we believe that as the sophistication of these payer and manufacturer arrangements increase, and the capture, integrity and timeliness of health-care data improves, these agreements will evolve to the ``sweet spot'' between controlling costs and encouraging the innovation of new medicines. Question. How can VBAs help lower what patients pay out-of-pocket? Answer. VBAs may lower patient out-of-pocket costs where, as a result of the VBA, the drug is placed on a preferred or lower formulary tier. In addition, as explained above, VBAs can potentially reduce overall healthcare costs, including patient out-of-pocket costs, by improving outcomes for patients through the reduction or elimination of the need for additional medicines and/or healthcare services. Question. Can Congress do more to allow for and encourage the use of VBAs? Answer. Yes. Congress can do more to allow for and encourage the use of VBAs. For example, Congress could adopt an exception to the Anti-Kickback Statute and enact measures to avoid unintended consequences under Medicaid price reporting. ______ Questions Submitted by Hon. John Cornyn Question. We continue to hear that rebates negotiated off of the list price of a drug are both good and bad. Pharmacy benefit managers and plans have argued that rebates are used to lower premiums across the board and that it is the best way to seek a price concession on otherwise expensive drugs. Your industry argues that these payers are insisting on higher rebates that can only be achieved by raising list prices. But patients often lose under this system, with out of pocket costs being tied to list price. Insulin patients appear to be routinely impacted by this perversity in the system. Please explain to the committee how your company would reduce list prices if rebates were no longer a part of the equation? Answer. BMS supports the HHS proposed rule to eliminate safe harbor protection for back-end rebates in Medicare Part D, and we believe it would lead to lower out-of-pocket costs. The goals of the proposed rule could be achieved through lower list prices, negotiated discounts at the point-of-sale, or some combination of these two approaches. While it is unclear how Part D plans and PBMs will react to the proposed rule, at this time, BMS envisions that we would offer point-of-sale discounts to Part D plans equivalent on average to the contracted rebate amount and will continue to assess the possibility of lowering list prices on a product-by-product basis. BMS would likely follow a similar approach if back-end rebates were eliminated from the commercial insurance market. Question. What assurance can you provide that you would in fact lower your prices? Answer. Please see answer to previous question. Question. What actions should be taken to ensure that patients are actually seeing the benefits of lower out of pocket costs? Answer. In order to ensure that patients receive the full benefits of manufacturer discounts, we support the proposed rule's requirement that manufacturer discounts be passed on to patients at the point-of- sale. In addition, we recommend implementing safeguards to protect consumers' access to medicines, to prevent increases in patients' out- of-pocket costs, and to ensure that patients' costs at the point-of- sale fully reflect manufacturer discounts. Question. If rebates are driving high list prices for drugs as drug manufacturers' claim, why do you think that Part B drugs, which have no PBM rebates, are also seeing significant price increases? Whose fault is that? Answer. The price increases for BMS Part B drugs have been largely in line with Medical CPI. We cannot comment on the Part B price increase practices of other manufacturers. ______ Questions Submitted by Hon. Todd Young re-evaluating business strategies in foreign countries Question. Since taking office, President Trump has made reducing drug prices one of his highest priorities--and has repeatedly spoken about his frustration with the U.S. subsidizing the costs of pharmaceuticals for the rest of the world. He has gone so far as to issue proposals, like the International Pricing Index (IPI) Model, in an attempt to bring down prescription drug prices. With the increased scrutiny of the industry and of the drug supply chain as a whole in the United States, have any of your companies re- evaluated your business strategy in foreign countries? Answer. Please see answer below. Question. If not, then why? Answer. Please see answer below. Question. If a proposal, like IPI, were implemented, would it force your companies to potentially ``walk away from the negotiating table when other countries demand low prices subsidized by America's seniors,'' as HHS Senior Advisor for Drug Pricing Reform John O'Brien has said? Answer. Please see answer below. Question. What are some of your ideas on how we can ensure Americans aren't shouldering the full cost of pharmaceuticals? Answer. BMS reviews its business strategies within and outside of the U.S. on a regular basis. BMS believes that all patients deserve access to life changing medicines. Because of these ethical considerations, BMS would not walk away from discussions about access to our medicines in foreign countries. We believe that the most likely outcome of IPI is further delays in access to life extending and innovative medicines within the referenced countries, resulting in, for example, lower cancer survival rates. The IPI proposal imposes price controls in the U.S. based on the policies of foreign countries with socialized health-care systems that often deny their citizens access to innovative medicines. Patients in many of the countries included in the reference basket wait significantly longer for new, life extending and innovative medicines to reach them. Outside of the U.S., reimbursement of new medicines can often take more than 2 years. In Greece, for example, only 8 percent of new cancer therapies are available, and on average it requires 32 months for these products to be available to patients. In comparison, in the U.S., 96 percent of new cancer drugs are available within 3 months of market approval. Eventually, the industry often accepts foreign prices which do not recognize the value and cost-effectiveness of our medicines because patients can wait no longer. BMS is committed to working with Congress and the administration to advance better, more effective ways to lower drug prices for patients. As an alternative to the IPI model, finalizing the proposed rebate rule would lower seniors' out-of-pocket costs at the pharmacy counter. Regulatory reforms at the FDA are leading to more medicine approvals and greater competition in the market. Value-based arrangements (VBAs) and indication-based pricing (IBP) can reduce the payer risk of exposure to failed outcomes, more closely associate drug costs and value, and make prescription medicines more affordable for patients. foreign countries' pricing and reimbursement Question. President Trump and Secretary Azar have both repeatedly described their frustrations with ``foreign freeloading'' of U.S. drugs in the last year. ``When foreign governments extort unreasonably low prices from U.S. drug makers, Americans have to pay more to subsidize the enormous cost of research and development. . . . It's unfair and it's ridiculous, and it's not going to happen any longer.'' Do you agree that because of foreign countries' pricing and reimbursement systems, U.S. patients and innovators are shouldering the burden for financing medical advances? Answer. Please see answer below. Question. How do foreign countries' pricing and reimbursement systems affect our prescription drug costs? Answer. Please see answer below. Question. Are foreign governments taking note of the concerns being raised by the Trump administration, and have they responded in any way? Answer. Please see answer below. Question. Has there been any noticeable change in any of our trade agreements since these concerns have been raised by the Trump administration? Answer. Drug pricing in markets outside of the U.S. must take into account significant differences in economic status, cultural beliefs and values, as well as differences in the local processes for setting prices, which vary significantly from market-to-market. Countries vary significantly in their per capita gross domestic product (GDP), their willingness to invest in, and provide rapid access to, health-care innovation, their focus on a single best average treatment for a population versus focusing on patient heterogeneity and preserving consumer choice and provider autonomy, and their tolerance and acceptability for optimal patient care. The countries selected for international comparison through the IPI model are not economically comparable with the U.S. Many of the countries in the IPI model, most notably Greece, the Czech Republic, and Italy, do not have comparable economies as measured in per capita gross domestic product (GDP). The significant difference in drug costs between the U.S. and other countries referred to by CMS in the IPI proposal is also seen with the comparative cost of physician services, hospital care, diagnostics, and medical devices. For example, according to a recent report by the OECD, hospital services in the U.S. cost 150 percent more than in Japan, France, Germany, Finland and Spain; 170 percent higher than in UK, Greece, and Italy. Through the USMCA and other trade actions, the Trump administration has taken steps to crack down on foreign violations of U.S. intellectual property rights. There remain, however, several practices that undermine U.S. intellectual property and violate existing trade deals. We need to continue to negotiate better trade deals with better enforcement that protect American medical innovations. medicaid closed formulary proposals Question. In an attempt to bring down drug costs, various States have been exploring whether to exclude certain drugs from its Medicaid program. For example, the State of Massachusetts' recently asked CMS for permission to create a closed formulary where the State Medicaid program would pick at least one drug per therapeutic class. CMS denied their waiver request citing violation of Federal law, but this proposal does bring up important questions on how to contain drug prices in State Medicaid programs. If the principles of the Medicare Part D program--including the necessary patient protections--were applied to State Medicaid programs, do you think it lower drugs costs while ensuring access to patients? Answer. It is unlikely that applying Part D principles to Medicaid would lower drug costs. Medicaid is already a lower-cost channel and patients have little to no copay obligations. medicaid ``best price'' Question. In the Trump administration's Blueprint, they suggested that because drug manufactures have to give Medicaid the ``best price'' on drugs, there is no incentive to offer deeper discounts to other payers--both government and commercial--than what is already offered under the Medicaid Drug Rebate Program. Does the Medicaid ``best price'' requirement encourage manufacturers to increase initial prices? Answer. For BMS, Medicaid ``best price'' is not a consideration in determining initial product pricing. Question. What, if any, changes would you suggest we make to the program? Answer. As clarification, prices offered to Medicare Part D plans are excluded from Medicaid ``best price,'' and therefore, manufacturers can offer deeper discounts to Part D without impacting Medicaid best price. More generally, BMS recommends the creation of an exemption from best price and AMP for select value based purchasing arrangements and greater clarity on best price and AMP reporting on issues related to such arrangements. outcomes-based contracts Question. In almost all of your testimonies, you highlight your support of outcomes-based contracts and how we need to be shifting our system toward that approach. How will these contracts lower drug costs for patients in both the near term and long-term? Answer. The goal and design of outcome-based contracts will vary depending on the specific drug and the therapeutic area/disease State which is being evaluated. In general, outcome-based contracts are designed to demonstrate the efficacy, safety, clinical superiority, cost savings and/or improvement in overall patient health outcomes. To the extent that outcomes-based contracts demonstrate improvement in clinical outcomes and/or reduction in overall health-care costs and facilitate access to appropriate medicines, patients will benefit from improved outcomes and reduced out-of-pocket costs, and Federal health- care programs will benefit from lower overall health-care costs. Question. How will they lower overall health-care costs for our Federal programs? Answer. Please see answer to previous question. Question. What have the preliminary results looked like so far? Answer. Eliquis has demonstrated a better safety profile than alternate therapies (less bleeding events) as proven through outcomes- based contracts using real world data. Oncology patients have higher rates of diagnostic testing done to monitor disease progression (as recommended by guidelines), through our testing based value-based contract. transparency/point of sale Question. In almost all of your testimonies, you express your support for the Trump administration's proposal to allow manufacturers to provide PBMs up-front discounts that are passed onto patients at the point-of-sale. Do you feel like this proposal will make the transactions within the drug supply chain more transparent? Answer. To the extent that discounts provided by manufacturers to PBMs and payers are passed through to the patients at the point-of- sale, transactions within the drug supply chain will be more transparent. Question. If so, would this transparency bring down drug costs-- overall and for specialty drugs? Answer. In terms of bringing down drug costs, the result of passing discounts through to patients at the point-of-sale will likely vary depending on the individual drug. We anticipate that patients who are prescribed high-cost, highly discounted drugs, primarily specialty drugs, and are subject to high co-insurance costs, will experience the greatest reduction in drug costs. the relationship between wholesalers and manufacturers Question. When talking about the pharmaceutical supply chain, a lot of focus has been placed on the Pharmacy Benefit Manager. But there's another side of the equation that I'd like to ask about. How do wholesalers negotiate pricing with manufacturers? Answer. Wholesalers and manufacturers negotiate distribution service agreements that include terms and fees. The fees are typically a percentage of list price. Question. What impact does this have on drug costs? Answer. It is BMS's understanding that the fees negotiated by wholesalers and manufacturers do not have a material impact on drug costs. Question. What incentives or disincentives do they have to contain price increases? Answer. This question is best answered by wholesalers. ______ Questions Submitted by Hon. Ron Wyden proposed rebate rule Question. As has been done in many other settings, drug manufacturers said during the hearing that one reason list prices for drugs are high is that pharmaceutical benefit managers (PBMs) demand larger and larger rebates in order for the drug to receive favorable placement on a formulary. You and your colleagues who testified during the hearing stated if the administration's proposal on changes to the anti-kickback safe harbor for pharmaceutical rebates took effect, your company would likely lower list price. Like many Oregonians, I am skeptical drug manufacturers would voluntarily lower their prices. Therefore, would you support legislation that would (1) make similar changes the administration has put forward related to Part D and Medicaid managed care, (2) change the rebate system in a similar way to the proposal for the commercial market, and (3) require drug makers to lower the list price of their drugs equal to the amount of rebates provided today? Answer. BMS supports the extension of rebate reforms to the commercial market. However, given the significant market change in the proposed Part D safe harbor change, we urge the committee to pursue an implementation timeline that will allow manufacturers, PBMs, plans, retail pharmacies, wholesalers, and other impacted parties to address the many operational challenges for the industry. We anticipate that the implementation of the safe harbor change in Part D will provide important learnings, but in order to extend these changes to the commercial market, industry will need additional lead time to do so. Given the many payers and channels in the health-care market, an individual drug has multiple net price points. Moreover, the goals of the proposed rebate rule can be achieved not only through lower list prices, but also through negotiated discounts at the point-of-sale, or through some combination of the two approaches. We believe the goals of the proposed rule can be best achieved by giving manufacturers the full range of options in their negotiations with plans and PBMs. Consequently, BMS would not support legislation that required drug makers to lower the list price of their drugs equal to the amount of rebates provided today. There may be instances where a reduction in product list price is warranted, but with or without a list price change, in order for patients to benefit fully from the changes, regulations would need to ensure that manufacturer discounts are passed through to patients at the point-of-sale and that patient out-of-pocket costs are based on product net price. medicaid drug rebate program Question. The Medicaid Drug Rebate Program (MDRP) requires manufacturers to provide a basic rebate and an additional inflationary rebate for both brand and generic drugs. The inflationary rebate is an increasingly substantial part of total rebates due in large part to large increases in drug prices that exceed inflation. Under current law, this inflationary rebate is capped at 100 percent of Average Manufacturer Price (AMP). This is the case even when manufacturers continue to raise their prices well above inflation. Please provide a list of all of your pharmaceutical products that have reached the Medicaid AMP rebate cap in any of the 20 quarters from January 1, 2014 through December 31, 2018. Answer. Please see answer below. Question. For each drug listed in response to question 1, please also provide a list of which quarters and years each drug hit the cap. Answer ------------------------------------------------------------------------ Product Quarter ------------------------------------------------------------------------ BARACLUDE TAB 0.5MG Q3 2014, Q4 2014, Q1 2015, Q2 2015, Q3 2015, Q4 2015 ------------------------------------------------------------------------ BARACLUDE TAB 1MG Q3 2014, Q4 2014, Q1 2015, Q2 2015, Q3 2015, Q4 2015 ------------------------------------------------------------------------ COUMADIN TAB 4MG Q1 2014, Q2 2014, Q3 2014, Q4 2014, Q1 2015, Q2 2015, Q3 2015, Q4 2015, Q1 2016, Q2 2016, Q3 2016, Q4 2016, Q1 2017, Q2 2017, Q3 2017, Q4 2017, Q1 2018, Q2 2018, Q3 2018, Q4 2018 ------------------------------------------------------------------------ COUMADIN TAB 4MG (1BTLX1000) Q3 2014, Q4 2014, Q1 2015, Q2 2015 US ------------------------------------------------------------------------ COUMADIN TAB 1MG Q1 2014, Q2 2014, Q3 2014, Q4 2014, Q1 2015, Q2 2015, Q3 2015, Q4 2015, Q1 2016, Q2 2016, Q3 2016, Q4 2016, Q1 2017, Q2 2017, Q3 2017, Q4 2017, Q1 2018, Q2 2018, Q3 2018, Q4 2018 ------------------------------------------------------------------------ COUMADIN TAB 2MG Q1 2014, Q2 2014, Q3 2014, Q4 2014, Q1 2015, Q2 2015, Q3 2015, Q4 2015, Q1 2016, Q2 2016, Q3 2016, Q4 2016, Q1 2017, Q2 2017, Q3 2017, Q4 2017, Q1 2018, Q2 2018, Q3 2018, Q4 2018 ------------------------------------------------------------------------ COUMADIN TAB 5MG Q1 2014, Q2 2014, Q3 2014, Q4 2014, Q1 2015, Q2 2015, Q3 2015, Q4 2015, Q1 2016, Q2 2016, Q3 2016, Q4 2016, Q1 2017, Q2 2017, Q3 2017, Q4 2017, Q1 2018, Q2 2018, Q3 2018, Q4 2018 ------------------------------------------------------------------------ COUMADIN TAB 7.5MG Q1 2014, Q2 2014, Q3 2014, Q4 2014, Q1 2015, Q2 2015, Q3 2015, Q4 2015, Q1 2016, Q2 2016, Q3 2016, Q4 2016, Q1 2017, Q2 2017, Q3 2017, Q4 2017, Q1 2018, Q2 2018, Q3 2018, Q4 2018 ------------------------------------------------------------------------ COUMADIN TAB 10MG Q1 2014, Q2 2014, Q3 2014, Q4 2014, Q1 2015, Q2 2015, Q3 2015, Q4 2015, Q1 2016, Q2 2016, Q3 2016, Q4 2016, Q1 2017, Q2 2017, Q3 2017, Q4 2017, Q1 2018, Q2 2018, Q3 2018, Q4 2018 ------------------------------------------------------------------------ COUMADIN TAB 2.5MG Q1 2014, Q2 2014, Q3 2014, Q4 2014, Q1 2015, Q2 2015, Q3 2015, Q4 2015, Q1 2016, Q2 2016, Q3 2016, Q4 2016, Q1 2017, Q2 2017, Q3 2017, Q4 2017, Q1 2018, Q2 2018, Q3 2018, Q4 2018 ------------------------------------------------------------------------ COUMADIN TAB 3MG Q1 2014, Q2 2014, Q3 2014, Q4 2014, Q1 2015, Q2 2015, Q3 2015, Q4 2015, Q1 2016, Q2 2016, Q3 2016, Q4 2016, Q1 2017, Q2 2017, Q3 2017, Q4 2017, Q1 2018, Q2 2018, Q3 2018, Q4 2018 ------------------------------------------------------------------------ COUMADIN TAB 6MG Q1 2014, Q2 2014, Q3 2014, Q4 2014, Q1 2015, Q2 2015, Q3 2015, Q4 2015, Q1 2016, Q2 2016, Q3 2016, Q4 2016, Q1 2017, Q2 2017, Q3 2017, Q4 2017, Q1 2018, Q2 2018, Q3 2018, Q4 2018 ------------------------------------------------------------------------ COUMADIN TAB 6MG US Q1 2014, Q2 2014, Q3 2014, Q4 2014, Q1 2015 ------------------------------------------------------------------------ AVAPRO TAB 75MG Q1 2014, Q2 2014, Q3 2014, Q4 2014, Q1 2015, Q2 2015, Q3 2015 ------------------------------------------------------------------------ AVAPRO TAB 150MG Q1 2014, Q2 2014, Q3 2014, Q4 2014, Q1 2015, Q2 2015, Q3 2015, Q4 2015, Q1 2016 ------------------------------------------------------------------------ AVAPRO TAB 300MG Q1 2014, Q2 2014, Q3 2014, Q4 2014, Q1 2015, Q2 2015, Q3 2015, Q4 2015, Q1 2016 ------------------------------------------------------------------------ AVALIDE TAB 150/12.5MG Q1 2014, Q2 2014, Q3 2014, Q4 2014 ------------------------------------------------------------------------ AVALIDE TAB 300/12.5MG Q1 2014, Q2 2014 ------------------------------------------------------------------------ medicaid drug rebate program compliance Question. I am concerned about recent reports and legal settlements surrounding drug manufacturers' failure to comply fully with the requirements of the MDRP. For example, an analysis by the U.S. Department of Health and Human Services Office of Inspector General found that between 2012 and 2016 taxpayers may have overpaid by as much as $1.3 billion for 10 potentially misclassified drugs. That is why I introduced the Right Rebate Act with Chairman Grassley to prevent drug manufacturers from manipulating Medicaid to increase their profits. However, I continued to be concerned about oversight and manufacturer compliance with the requirements of the Medicaid Drug Rebate Program. Accordingly, please describe the following: Your company's current compliance plan and procedures used to ensure compliance with the requirements of the Medicaid Drug Rebate Program including internal audits or other checks you use to identify compliance vulnerabilities. Answer. The Company routinely assigns new employees working in the government pricing area formal training on U.S. government pricing and contracting. This training includes an overview of the Medicaid Program obligations and requirements. BMS also maintains policy and procedural documents which govern compliance relative to the Medicaid Drug Rebate Program. In addition, BMS periodically holds informal training sessions as part of departmental and other internal meetings, where compliance training is provided on topics relevant to the Medicaid Drug Rebate Program. BMS has also identified key controls related to the Medicaid Drug Rebate Program which are independently tested as part of the Company's Sarbanes-Oxley controls. As part of these controls, all Medicaid pricing submissions are reviewed and approved by the appropriate Company management. In addition, BMS Global Internal Audit and Assurance periodically conducts internal audits of the Company's operations, which include activities that support the Medicaid Drug Rebate Program. Question. Any past or ongoing issues of non-compliance. Answer. There are no ongoing issues of non-compliance with the Medicaid Drug Rebate Program, nor were there any within the past 5 years. (BMS interprets the question as asking for a reasonable period in the past, and has selected 5 years). Question. Any corrective actions taken to address identified problems or issues of non-compliance with the MDRP and how such steps were communicated to the Centers for Medicare and Medicaid Services. Answer. There are no ongoing issues of non-compliance with the Medicaid Drug Rebate Program, nor were there any within the past 5 years. (BMS interprets the question as asking for a reasonable period in the past, and has selected 5 years). Question. Any steps taken to improve compliance and ensure that all Medicaid drug rebates owed to the Federal Government and the States are paid in full. Answer. In addition to the compliance and audit activities already outlined, the BMS Government Pricing team conducts regular cross- functional information sharing meetings in order to facilitate communication within the organization, to gather all relevant pricing and contracting information, and to provide education that is focused on ensuring compliance with our Medicaid reporting obligations. The Government Pricing team also conducts quarterly Medicaid Best Price review meetings with key members of the pricing and contracting organization and requires that leaders of key functions within the pricing and contracting organization sign-off on quarterly Medicaid Best Price information prior to the Company's final. Additionally, the Company has made significant investments in the systems which are used to support the calculation and payment of Medicaid rebates to help ensure greater compliance, standardization and automation of our processes. BMS also maintains a Compliance and Ethics hotline and encourages all employees to raise potential compliance concerns so that they can be investigated and addressed. More specifically with regard to the payment of Medicaid drug rebates, based on the current portfolio of active drugs, all BMS drugs are classified as Innovator Single Source or Innovator Multiple Source drugs which are subject to the higher basic rebate calculation. When BMS launches a new drug that is subject to Medicaid reporting, the drug classification is reviewed as part of the Medicaid submission approval process. To the extent that BMS has questions on MDRP compliance or on interpretative approaches to MDRP price reporting, we communicate with the Centers for Medicare and Medicaid Services. bonus payments tied to specific drugs Question. I am concerned by the potential for employee financial incentives to encourage high launch prices and price increases for prescription drugs. Is your salary, bonus, or other compensation tied to sales or revenue targets of a single product your company sells? Has it ever been? If yes, please state the product or products to which your salary, bonus or other compensation was tied. Answer. No, Dr. Caforio's salary and bonus are not tied to sales or revenue targets for a single product. Dr. Caforio's compensation is tied in part to the revenue of the Company as a whole. Please see answer below. Question. Is your salary, bonus, or other compensation tied to either revenue or net income of the company as a whole? Has it ever been? If yes, please explain what assumptions about price increases are used when the compensation committee sets revenue or net income goals. Does the compensation committee provide any guidance to executives in regards to the amount of revenue that the company will generate from price increases versus volume growth? Answer. Dr. Caforio's compensation is tied in part to the revenue of the Company as a whole. The revenue metric is based on the overall Company target for the applicable performance period (annual for annual bonus and longer-term, 3 years for Performance Share Units), which typically includes assumptions concerning both price changes and volume growth. Over the last few years, BMS' revenue growth has been primarily attributable to increased volume arising from increased demand for our products rather than price increases. Dr. Caforio's compensation is reviewed and recommended by the Compensation and Management Development Committee, which is a committee consisting of only independent directors, and approved by at least three-fourths of the independent directors of our Board of Directors. The Compensation Management and Development committee annually completes a thoughtful and rigorous evaluation of the Company's executive compensation program to ensure that the program is aligned with our mission and delivers shareholder value, while not encouraging excessive or inappropriate risk-taking by our executives. When determining metrics and setting incentive plan targets each year and for 3 year performance period, the committee is aware of the risks associated with drug pricing, among other risks, and ensures our plans do not incentivize risky behavior in order to meet targets and goals. net prices Question. In your testimony you stated, ``for this reason, the average net pricing across our U.S. portfolio of medicines increased by 5 percent of the last year-over-year for the last 5 years. Importantly, it did not increase at all in 2018 and we expect that it will not increase in 2019.'' Please describe how the company's year-over-year aggregate net price is calculated. Please also specifically address the following questions. Answer. Dr. Caforio testified that BMS's average net pricing across the company's U.S. portfolio increased by 5 percent or less year-over- year for the last 5 years. Please see the answer below for a description of how year-over-year net price is calculated. Question. How many products are included in the calculation of the average net price change? What was the median net price change? Answer. Approximately 20 products are included in the calculation of the average net price change. The median net price change over the last 5 years is 3.4% based on the following net price change per year: 2018 2017 2016 2015 2014 (0.3%) 1.6% 5.2% 3.4% 4.0% Question. Is net price weighted? If so, how? For example, in determining the aggregate net price does the company assign different weights to different products based on volume or other factors? Are ``on patent'' and ``off patent'' drugs weighted identically? Are other statistical weights used or are all products treated equally? Answer. Net price is weighted according to the product's sales relative to total BMS sales. Year-over-year change in Net Price = Change in List Price + Change in effective discount rate across all channels. Patent and off-patent drugs are treated equally in the calculation. Question. Does the figure that you provided during your testimony account for U.S. prices, international prices, or both? Generally speaking, when your company reports net price changes, does it differentiate between U.S. and international prices? Answer. The figure included in Dr. Caforio's testimony accounted for U.S. prices. Yes, BMS discloses by region (i.e., U.S., Europe, Rest of World) in our quarterly 10Q and Annual 10K filings. However, the only net price changes specifically outlined (i.e., in percentage terms) is for the U.S. Question. Please list the five drugs your company sold in the U.S. that had the greatest year-over-year net price increase in 2018, noting the increase for each drug by dollar figure and percentage. Please list the five drugs your company sold in the U.S. that had the lowest year- over-year net price increase (and/or the greatest decrease) in 2018, noting the increase (or decrease) for each drug by dollar figure and percentage. Answer. This question calls for information that BMS does not disclose publicly and considers to be competitively sensitive. Question. For 2018, what was the average net price change in the U.S. market for (1) drugs with no competition, (2) drugs with only branded competition, and (3) drugs with generic competition? Answer. This questions calls for information that BMS does not disclose publicly and considers to be competitively sensitive. Question. You stated that average net price increased 5 percent in 2017, but did not increase in 2018, and that you do not expect it to increase in 2019. What factors contributed to the change from 2017 to 2018? What would the net price increase have been if your company excluded the impact of drugs like Reyataz and Sustiva, which lost exclusivity in the United States at the end of 2017, and Daklinza, which the company reported losing revenue on? Answer. Dr. Caforio testified that BMS's average net pricing across the Company's U.S. portfolio increased by 5 percent or less year-over- year for the last 5 years. Average U.S. net price remained unchanged from 2017 to 2018 (i.e., 0 percent net price increase from 2017 to 2018), because discounts across all channels increased at a rate higher than list price increased. If drugs which lost exclusivity, like Reyataz, Sustiva and Daklinza, were excluded, the net price change would still be 0 percent. ______ Questions Submitted by Hon. Robert Menendez Question. When new products enter the market, do drug companies set high initial rebates and then provide deep rebates in order to gain access to insurance plan's formularies? Answer. BMS does not. We cannot comment on the pricing practices of other manufacturers. Question. If CMS finalizes the rebate rule, do you anticipate future products entering the market with significantly lower initial list prices? Answer. If CMS were to finalize the rebate rule, the impact on list prices of future products would likely differ by product depending on such factors as the clinical profile of the product, competition, market dynamics, and the channel into which the product is primarily sold. As noted above, the goals of the proposed rule could be achieved through lower list prices, negotiated discounts at the point-of-sale, or some combination of these two approaches. ______ Questions Submitted by Hon. Thomas R. Carper Question. What are your recommendations for lowering prices for the 40 percent of drugs that do not offer rebates in Medicare Part D? Answer. BMS believes that market-based reforms are the best way to lower costs and maintain the appropriate incentives for innovation. BMS supports policies that enable payers to negotiate innovative and flexible ways to pay for medicines, including value-based purchasing arrangements. Additionally, we need to ensure generics are available whenever permissible under our system. BMS notes also that even manufacturers pay coverage gap discounts for all Part D drugs regardless of whether a payer rebate is provided for that drug. Question. In the health insurance plans that you offer your employees, do you ask your insurers to pass through the full manufacturer rebates to the beneficiaries? Answer. Based on the contract negotiated with the PBM with which BMS has contracted, BMS has elected to reinvest the rebates we would otherwise have received from the PBM to reduce the per claim cost for brand drugs across the entire population of members we cover. BMS provides health care coverage to approximately 10,000 active employees, 4,000 retirees and 18,000 spouses and other dependents. Under this reinvested model, those rebate dollars are applied to reduce the negotiated rate our enrollees pay for brand drugs. This means that the PBM charges the plan a lower negotiated rate for all branded drugs (not just those associated with specific rebates), benefiting a broader portion of our covered population. Since our health plan benefit design uses a coinsurance for member cost sharing, this lower negotiated drug cost enabled by the application of the rebate value, reduces the coinsurance amount our members pay for their medications at the pharmacy counter. Question. The systems for pricing and distributing drugs are opaque and difficult to understand. What are your recommendations for increasing transparency in how your companies set the list prices for drugs, and for improving transparency in the supply chain for prescription drugs? Would you support Federal standards for transparency in setting the list prices for drugs? Answer. BMS intends to provide added transparency around the list prices for its medicines. We are creating pricing pages for all of our advertised medicine websites to include list price and additional information on out-of-pocket costs and support programs. Any DTC TV ads will direct patients to the site through a web link. Our plan is to have this information available by April 15, 2019. We solicited feedback from the patient community to ensure the resources we provide about pricing are meaningful to patients. The research suggests patients may misinterpret list price information in a television advertisement without additional context. BMS is complying with the recently enacted California drug price transparency legislation and would like to work with the committee on similar legislation at the Federal level, or legislation similar to the SPIKE Act (S. 474), both of which are intended to require manufacturers to disclose price increases above a certain threshold. Question. In nearly every sector of the health-care industry, Medicare, Medicaid, employers, and insurers are moving away from fee- for-service payments to reimbursements based on value and performance. Prescription drugs and medical devices were the glaring exceptions to this trend until recently. How many of your drugs are included in value-based contracts and how many patients are benefiting from them? How do these value-based contracts work to lower drug prices for both patients and taxpayers? Answer. Currently, BMS has value-based contracts for two products. Approximately 39 million patients are eligible for potential coverage under those contracts. The goal and design of outcome-based contracts will vary depending on the specific drug and the therapeutic area/disease state which is being evaluated. In general, outcome-based contracts are designed to demonstrate the efficacy, safety, clinical superiority, cost savings and/or improvement in overall patient health outcomes. To the extent that outcomes-based contracts demonstrate improvement in clinical outcomes and/or reduction in overall health-care costs, patients will benefit from improved outcomes and reduced costs, and the Federal programs will benefit from lower overall health-care costs. Question. Last year, Senator Portman and I did an investigation on the pricing of an opioid overdose reversal drug called EVZIO, manufactured by Kaleo. Kaleo increased the price of EVZIO from $575 in 2014 to $4,100 in 2017. We found that the best price Medicare was able to get for EVZIO, about $4,000, was much higher than the price other Federal programs and private insurers were able to get. It seemed that Kaleo was able to get this higher price of $4,000 from Medicare by helping doctors fill out paperwork showing that the drug was medically necessary, even though there are cheaper alternatives on the market. As a result of the investigation, Kaleo announced it will bring a generic version of the drug to market at only $168 per pack. Are any of your companies providing medical necessity paperwork to doctors in order to get your drugs covered by Medicare? Answer. BMS offers patient support programs that help eligible patients who are prescribed our medicines obtain access to those medicines. This includes assisting patients in navigating the insurance approval process. Consistent with longstanding OIG guidance and common industry practices, BMS does provide the template forms required by insurers for use in making coverage determinations, but BMS does not provide medical necessity content. That content must be independently provided by the prescribing health-care provider. Question. In 2017, the Rand Corporation estimated that biosimilar drugs, which are competitors to complex, biologic drugs, could save the United States more than $50 billion over the next decade. Some of you have also argued that increasing the use of biosimilar drugs would help lower drugs costs for consumers and taxpayers. What is delaying the uptake of biosimilar drugs in the United States? What policies do you recommend to increase the development of biosimilar drugs? Answer. BMS does not have a biosimilar or a branded product with biosimilar competition, and consequently, is not in a position to offer first-hand insight. ______ Questions Submitted by Hon. Benjamin L. Cardin Question. The United States is one of the only countries in the world to allow prescription drug manufacturers to advertise directly to consumers through magazines, billboards, radio, and television commercials. While I will not argue that it is beneficial to educate consumers about an unfamiliar disease and encourage them to seek medical help, most commercials from all of your companies recommend asking about a specific brand name drug, not a medical condition. Furthermore, even if your advertisements follow all FDA rules and list medication side effects, they also almost always list these while a smiling, apparently healthy person is walking on a beach. Researchers say that this type of imagery, combined with viewing hours of drug commercials each month, leads consumers to underestimate the risks associated with medications. For the past decade, studies have shown that aggressive direct-to-consumer advertising is associated with rising drug prices and an increase in inappropriate drug prescriptions. Question. Since researchers have concluded that consumers are misunderstanding the benefits and risks described in your ads, what further policies could help you and your colleagues ensure that you are educating patients in a clear manner? Answer. BMS engages in DTC TV advertising selectively and only when we think it will help educate patients. Our DTC TV advertising is submitted to the FDA for advisory comments prior to being broadcast in accordance with FDA guidance. BMS believes that our DTC advertising clearly and appropriately communicates the benefits and risks of our medicines. BMS believes responsible DTC communications play a critical role in educating patients and families about treatment options and encourages them to have an informed discussion with their physician about the best treatment for their needs. BMS would be open to considering any additional policy proposals that further facilitate the achievement of this goal. pharmaceutical companies continue to raise prices Question. As you are well aware, high prescription drug prices are the number one concern for Americans and their families. According to the Organization for Economic Cooperation and Development, the average American spends around $1,208 annually on prescription drugs. There have been several instances where brand name or even generic drugs that have been on the market for years continue to increase in price. One of the most well-known examples is Mylan's increase of the price of EpiPen from less than $100 in 2007 to more than $600 in 2016. Another example, is the ever-increasing price of insulin. Sanofi increased the price of a vial of Lantus from $88.20 in 2007 to $307.20 in 2017. And those are just a small sample of price increases. Why don't we see price decreases for drugs that have been on the market for years without new formulations or added benefit? Answer. Although list prices for a drug without new formulations or added benefits may not decrease over time, in our experience, net prices generally decrease over time and/or volume decreases significantly as generics enter the market. pay for delay Question. Pay for delay is a tactic that more and more branded drug manufacturers have been using to stifle competition from lower-cost generic manufacturers. This allows you to sidestep competition by offering patent settlements that pay generic companies not to bring lower-cost alternatives to market. These ``pay-for-delay'' patent settlements benefit both brand-name pharmaceutical companies by helping them avoid costly patent litigation and general manufacturers by rewarding them a hefty sum to delay entering the market with a cheaper drug alternative. However, these deals do not benefit consumers. According to an FTC study, these anticompetitive deals cost consumers and taxpayers $3.5 billion in higher drug costs every year. Does your company partake in pay-for-delay settlements? Answer. No. Question. Why would a pharmaceutical company enter into a pay-for delay agreement? Answer. As stated above, BMS does not enter into any pay-for-delay settlements. We cannot comment on the actions and motivations of other manufacturers. Question. Do you think these agreements stifle competition and prevent generic alternatives to your branded medications? Answer. BMS agrees that patent settlement agreements that have substantial payments going from innovators to generics, and are solely intended to delay competition, are anticompetitive. In contrast, agreements that do not contain such substantial payments and properly balance litigation considerations often lead to earlier generic entry than patent expiration. drug rebate rule Question. In January, the Department of Health and Human Services' (HHS) Office of Inspector General (OIG) promulgated a new regulation to remove regulatory safe harbor protections under the Anti-Kickback Statute (AKS) for rebates on prescription drugs rebates paid by manufactures to PBMs under Medicare Part D and for Medicaid managed care organizations (MCOs). The OIG proposal attempts to ban most rebates by eliminating their regulatory protections. The rule is predicted to increase net drug costs in its early years. The CMS actuaries estimate it would cost $196 billion over 10 years. Despite this high price tag, the beneficiary benefits are limited. The proposed rule notes that under the CMS Actuary's analysis, the majority of beneficiaries would see an increase in their total out- of-pocket payments and premium costs; reductions in total cost sharing will exceed total premium increases. I wanted to ask a question about the administration's rebate rule, which I understand that many of the drug manufacturers, and your main trade association, strongly support. According to an analysis of the rule by the Office of Actuaries at CMS, drug manufacturers are likely to initially retain 15 percent of the current rebates as higher net drug prices. Given that estimate, can you provide the committee with any assurances that prices will not increase under this proposed rule? Answer. BMS supports HHS's proposed rule because BMS believes it will lower patient costs at the point-of-sale and ensure patients realize the benefit of manufacturer discounts. We do not anticipate that manufacturer average net prices will increase as a result of this rule. ______ Questions Submitted by Hon. Sherrod Brown Question. According to an article recently published in the Journal of the American Medical Association, medical marketers spent nearly $30 billion dollars in 2016, up from $17 billion in 1997. Direct-to- Consumer (DTC) advertising had the biggest percentage increase: from $2.1 billion, or 11.9 percent of all medical marketing, in 1997 to $9.6 billion, or 32 percent of total spending, in 2016. Can you please provide what your ratio of spending on sales and marketing to research and development is today? Answer. BMS does not disclose sales and marketing investments separately. In 2018, BMS marketing, selling and administrative expenses were $4.6 billion, which is inclusive of sales and marketing, and R&D expenses were $6.3 billion. That ratio is approximately 7 to 10. price-gouging Question. Sanofi, as I understand it, has made a pledge to the public to limit its price increases to the national health expenditures growth projection. Would your company commit to a cap on annual price increases as part of your PhRMA membership criteria? Answer. It is BMS's understanding that a cap on annual price increases as part of PhRMA membership would raise significant antitrust concerns. Question. What policies would you propose to help ensure lower launch prices for new drugs? Answer. BMS does not believe that government policies should govern launch pricing of new drugs. Payers, providers, patients, and the marketplace should freely assess the value of new innovative therapies relative to their improvement in outcomes and impact to total cost of care. At BMS, we believe the prices of our medicines reflect the value they bring to patients, healthcare providers, payers, and society as a whole. transparency Question. In many of your testimonies, you mentioned that the current system of pharmacy benefit manager (PBM) back-end rebates do not rarely results in a scenario where the PBM passes on savings to consumers at the point of sale (POS). The administration recently proposed a rule to eliminate the anti-kickback statute safe harbor protections for these drug rebates. Do you agree that greater transparency should be required to understand how manufacturers and PBMs are negotiating prices and rebates to ensure that savings are passed down to beneficiaries? Answer. Yes, BMS agrees that manufacturer's net prices should be transparent to and passed through to beneficiaries. BMS also believes that this transparency should be required for all entities in the health-care market. pbms Question. An Axios article from March 7, 2019 highlights the fact that, while ``pharmaceutical companies put a lot of the blame for high drug prices on pharmacy benefit managers,'' many large pharmaceutical companies ``rely on PBMs to manage their own health care benefits.'' In your role as an employer, does your company contract with a pharmaceutical benefit manager (PBM) to administer the prescription drug benefits for your employees and negotiate lower drug costs on your behalf? Answer. Yes. Question. For those of you who do use a PBM to help manage the prescription drug benefit for your employees, how do you utilize the rebates your PBM negotiates to lower health care costs or drug costs for your employee plans and what does your company do with that savings? Specifically, do the savings go toward lowing premiums? Answer. BMS uses a PBM for our self-funded Pharmacy Benefit Program, which is part of our overall healthcare plan. The PBM offers the option of direct point-of-sale rebates, however, based on the contract negotiated with the PBM, BMS has elected to reinvest the rebates we would otherwise have received from the PBM to reduce the per claim cost for brand drugs. Under this reinvested model those rebate dollars are applied to reduce the negotiated rate our enrollees pay for branded drugs. This means that the PBM charges the plan a lower negotiated rate for all branded drugs (not just those associated with specific rebates). Since our health plan benefit design uses a coinsurance for beneficiary cost sharing, this lower negotiated drug cost enabled by the application of the rebate value, reduces the coinsurance amount our members pay for their medications at the pharmacy counter. Under this model, a greater number of participants benefit from the value of the rebates. Question. For those of you who do use a PBM to help manage the prescription drug benefit for your employees, does your PBM offer point-of-sale rebates to your employees? Answer. Please see answer to previous question. ______ Questions Submitted by Hon. Sheldon Whitehouse Question. Please describe any policy changes you support that would result in your company lowering the list prices of its drugs. Answer. BMS supports the HHS proposed rule to eliminate safe harbor protection for back-end rebates in Medicare Part D, and we believe it would lead to lower out-of-pocket costs. The goals of the proposed rule could be achieved through lower list prices, negotiated discounts at the point-of-sale, or some combination of these two approaches. While it is unclear how Part D plans and PBMs will react to the proposed rule, at this time, BMS envisions that we would offer point-of-sale discounts to Part D plans equivalent to the contracted rebate amount and will continue to assess the possibility of lowering list price on a product-by-product basis. Our ability to lower list prices, however, is constrained by the fact that the HHS proposed rule does not apply to the commercial insurance market, where we anticipate back-end rebates to continue for the foreseeable future. Question. How much does your company's research and development portfolio rely on taxpayer-funded research conducted by the National Institutes of Health (NIH)? How many of your company's products are based, at least in part, on NIH research, and how many are the result of research funded solely by your company? Answer. Government institutions such as NIH and NCI do critically important basic research. However, the most significant investment behind any molecule is the clinical development program, which is usually when a pharmaceutical company comes into the development process. On average it takes 10 to 15 years and about $2.5 B to bring a medicine to patients, depending on the asset, therapeutic area, number of indications, and other factors. This is highly dependent on the stage of the molecule/asset when it comes to BMS. There is also considerable risk of failure given the complexity of clinical development. Only about 12 percent of drugs that make it to Phase 1 clinical trials result in an approved product. Question. In each of the last 5 years, how much has your company spent on research and development versus the advertising and marketing of your products? Answer. BMS does not publicly disclose specific advertising and marketing expenditures. The figures below are for marketing, sales and administrative expenses, which includes advertising and marketing expenditures. 2018 spend: Marketing, selling, and administrative expenses: $4.6 billion Research and development expenses: $6.3 billion 2017 spend: Marketing, selling, and administrative expenses: $4.8 billion Research and development expenses: $6.5 billion 2016 spend: Marketing, selling, and administrative expenses: $5.0 billion Research and development expenses: $5.0 billion 2015 spend: Marketing, selling, and administrative expenses: $4.8 billion Research and development expenses: $5.9 billion 2014 spend: Marketing, selling, and administrative expenses: $4.8 billion Research and development expenses: $4.5 billion Question. During the hearing, you mentioned that your company would be likely to lower the list prices of its drugs if the recent proposal by the Trump administration to change the current system of rebates was extended to the private market. If the policy was extended to the private market, how large would the list price reductions be relative to the size of the rebates your company is currently providing? Answer. While it is unclear how health plans and PBMs would react if the HHS proposed rule's policy were extended to the private market, at this time, BMS envisions that we generally would offer point-of-sale discounts to health plans equivalent on average to the contracted rebate amount and would continue to assess the possibility of lowering list price on a product-by-product basis. In the absence of list price reductions, the policy requirement that manufacturer discounts be passed on at the point-of-sale would accomplish the goal of reducing patient out-of-pocket costs. Question. How will this proposal affect how your company sets the list prices for new drug products? If the proposal is finalized and not extended to the private market, will your company make any list price reductions? If so, how large would the reductions be relative to the size of the rebates your company is currently providing? Answer. While it is unclear how health plans and PBMs would react if the HHS proposed rule were finalized and not extended to the private market, at this time, BMS envisions that we would offer point-of-sale discounts to Part D plans equivalent on average to the contracted rebate amount and would continue to assess the possibility of lowering list price on a product-by-product basis. In the absence of a list price reduction, the proposed rule's requirement that manufacturer discounts be passed through to patients at the point-of-sale would accomplish the goal of reducing patient out-of-pocket costs. ______ Question Submitted by Hon. Maggie Hassan Question. In June of 2018, the Medicaid and CHIP Payment and Access Commission (MACPAC) unanimously recommended under Recommendation 1.1 in their annual report to Congress that Congress remove the statutory requirement that manufacturers blend the average manufacturer price (AMP) of a brand drug and its authorized generic.\1\ --------------------------------------------------------------------------- \1\ MACPAC, ``Improving Operations of the Medicaid Drug Rebate Program,'' https://www.macpac.gov/wp-content/uploads/2018/06/Improving- Operations-of-the-Medicaid-Drug-Rebate-Program.pdf. This requirement created an unintended loophole. Rather than use the price of the authorized generic, drug companies can sell its authorized generic to a corporate subsidiary at an artificially lower price, and use that lower price to bring down the AMP, which in turn --------------------------------------------------------------------------- lowers the rebate obligation. Does your company engage in this practice? Has your company ever engaged in this practice in the past? Answer. No. BMS does not have any authorized generics with its own corporate subsidiary. ______ Questions Submitted by Hon. Catherine Cortez Masto Question. Dr. Caforio, your company has entered a merger agreement to acquire Celgene, which makes the cancer drug Remlivid. The price of Remlivid was hiked nearly 20 percent in 2017, 5 percent last year, and another 3.5 percent just last month.\2\ Remlivid was also high on a list of brands whose manufacturers have refused to provide generic companies with the samples they need to submit an FDA application. Celgene refused 13 such inquiries, despite FDA's assurance that they were safe to share.\3\, \4\ Today Remlivid stands as a $70,000 sole source drug with no competition.\5\ You mention increasing access to generics as a priority in your testimony. In a case were Remlivid falls under your purview, what specific actions will you take to promote generic competition of that drug? --------------------------------------------------------------------------- \2\ https://www.reuters.com/article/us-celgene-results/celgene- profit-tops-expectations-will-limit- future-price-hikes-idUSKBN1KG1IC. \3\ https://www.fda.gov/Drugs/DevelopmentApprovalProcess/ HowDrugsareDevelopedandApp roved/ApprovalApplications/AbbreviatedNewDrugApplicationANDAGenerics/ ucm607738.htm ?utm_campaign=FDA%20publishes%20list%20of%20inquiries%20from%20generic%2 0drug%20 applicants%20about%20RLD%20access&utm_medium=email&utm_source=Eloqua. \4\ https://www.npr.org/sections/health-shots/2018/05/17/571986468/ how-a-drugmaker-gamed-the-system-to-keep-generic-competition-away. \5\ https://twitter.com/megtirrell/status/1016769284025016320. Answer. BMS believes it is important to ensure generics are made available whenever that is permissible under our system, and supports the administration's focus on increasing the approval of generics. As part of that system, it is important that generic companies perform the --------------------------------------------------------------------------- needed testing to ensure product quality and patient safety. Until the transaction closes, BMS and Celgene will continue to operate as separate companies. BMS thus does not know and cannot comment on Celgene's practices as they relate to generic manufacturers. Once the transaction closes, BMS' practices with regard to generic manufacturers, including the provision of samples, will govern the combined portfolio. Question. As a portion of your revenue, for what percentage of the drugs in your portfolio do you offer no rebates? Based on the drugs in your pipeline, do you foresee that portion growing? For those drugs is your list price equal to your net price? Answer. Although the level of rebates varies by product and channel, BMS pays rebates for all products in our portfolio. Question. Do you invest more in R&D than you generate in US sales revenue? Please include specific figures. Answer. BMS invested $6.3 billion in R&D in 2018, which includes the discovery and development of new medicines. U.S. sales for 2018 were $12.5 billion. Question. Do you invest more in R&D than you spend on marketing and administration? What company functions do you consider to be included in administration? Please include specific figures. Answer. BMS does not publicly disclose specific marketing and administration expenditures. The figures below are for marketing, sales and administrative expenses, which includes marketing and administration expenditures. 2018 spend: Marketing, selling, and administrative expenses: $4.6 billion Research and development expenses: $6.3 billion 2017 spend: Marketing, selling, and administrative expenses: $4.8 billion Research and development expenses: $6.5 billion 2016 spend: Marketing, selling, and administrative expenses: $5.0 billion Research and development expenses: $5.0 billion 2015 spend: Marketing, selling, and administrative expenses: $4.8 billion Research and development expenses: $5.9 billion 2014 spend: Marketing, selling, and administrative expenses: $4.8 billion Research and development expenses: $4.5 billion Question. Do you invest more in R&D than you spend on marketing and sales? What company functions do you consider to be included in sales? Please include specific figures. Answer. BMS does not publicly disclose the functions included in sales nor specific marketing and sales expenditures. Please see the answer to the prior question for R&D and marketing, selling and administrative expenses. Question. Why do you advertise for the drugs you manufacture? What factors do you consider in choosing which drugs you advertise? Answer. BMS believes responsible DTC communications plays a critical role in educating patients and families about treatment options, and encourages them to have an informed discussion with their physician about the best treatment for their needs. As a company, BMS engages in DTC TV advertising selectively and only when we think it will help educate patients. Currently BMS is engaging in DTC TV advertising for one product (Eliquis). ______ Prepared Statement of Kenneth C. Frazier, Chairman and Chief Executive Officer, Merck and Company, Inc. Mr. Chairman, Senator Wyden, and members of the committee, thank you for the opportunity to appear today. Merck's mission is to save and improve lives around the world by bringing forward breakthrough medicines and vaccines, and ensuring they are available and affordable to patients who need them. Merck is a science-based company that exists to help solve the world's most vexing medical challenges. We have a long history of doing this, from the development of most of the common childhood vaccines, to bringing the first protease inhibitor to patients, turning AIDS from a death sentence to a chronic disease, to developing the first statin, which led to significant reductions in the negative health effects of high cholesterol. This legacy of invention continues today. Research is at the core of who we are and what we do. Last year, Merck invested nearly $10 billion in research and development toward our mission of preventing, treating, and curing disease, and since 2010 we've invested nearly $70 billion in these efforts. Our more than 12,000 researchers are focused on cancer, infectious diseases, and Alzheimer's, as well as other major health challenges that affect large numbers of people around the world. For our breakthrough immuno- oncology drug Keytruda alone we have over 900 clinical trials under way. In pursuit of these efforts, we are also investing significantly in infrastructure here in the United States. We have invested more than $5 billion in the last five years, and we plan to invest $9 billion more over the next few years to increase manufacturing capacity and open two new discovery research centers. Our mission is to go where the science leads us, which means we don't allocate resources only to addressing diseases in wealthy countries; we focus our efforts on conditions that significantly impact people living all over the world. For instance, we are proud to have deployed 70,000 doses of our experimental Ebola vaccine in the Democratic Republic of the Congo, working in partnership with the Centers for Disease Control and Prevention, the Biomedical Advanced Research and Development Authority, and the Department of Health and Human Services. For efforts such as this there is no commercial opportunity, but we pursue them because these are the challenges that Merck was created to tackle. At the end of the day we do all of this to serve patients. We understand that patients are having a harder and harder time affording their health care, including their prescription medicines. As a result of robust negotiation and competition in the marketplace, medicine costs are growing at the slowest rate in years, but the system is still not working for patients who are too often being asked to pay more out- of-pocket due to the complex system of pricing, distribution, and insurance. I am here today to suggest a few ways that we can address this problem together. First, we want to be clear that our industry has a duty to be responsible in our pricing practices and contribute to solutions that address the affordability problems facing patients. We have all heard the egregious examples of irresponsible behavior. At Merck, we have a history of responsible pricing. To help increase transparency about our pricing practices, we publicly disclose information about our prices in the U.S. and the rebates and discounts we provide to payers--including insurers, pharmacy benefit managers, and the government. Last year, we pledged that we will not increase our average net prices for our portfolio by more than the rate of inflation annually. From 2010 to 2017, Merck's average net price increase across our portfolio each year has been in the low to mid-single digits. In fact, our average net price declined in 2017 by almost 2 percent. In 2017, the average discount for our medicines and vaccines was more than 45 percent lower than the list price. Despite these very large discounts, patients do not see a commensurate benefit. In fact, patient out-of- pocket costs continue to rise, and patients are being asked to shoulder more of their drug costs than other health-care services. Second, we must ensure that patients get the benefit of the large rebates and discounts that manufacturers are paying to PBMs and insurance companies. The incentives in the current system are badly misaligned. As a result, the current system of drug competition that depends on rebating is not working for patients. The growing gap between our list prices and our net prices that results from rebating has created incentives for supply chain entities to favor products with higher list prices. For instance, in 2016, we introduced our hepatitis C therapy, Zepatier, at a list price that was 42 percent below the price of the therapy that was the standard of care. However, due to the misaligned incentives in the supply chain that create a preference for higher priced products, we had difficulty gaining access for patients in certain market segments. This kind of misalignment can have a significant negative impact on patients because their cost-sharing is often based on the list price of a drug, even when insurance companies and PBMs are paying a fraction of that price. Our current system that incentivizes high list prices and large rebates as a mechanism to keep insurance premiums low means that sick patients are essentially subsidizing healthy patients. In this way, our insurance system is broken. We urge you to support action to make sure that all patients benefit from the discounts we make available. Third, we can significantly reduce spending on pharmaceuticals, especially for patients, by ensuring that we have a viable market for biosimilars in the United States. We believe, like with traditional small molecule medicines, generic competition after a reasonable period of exclusivity will create headroom for patients to afford the newest, most innovative medicines. Research shows that generics and biosimilars are expected to drive savings of $105 billion through 2022 in the U.S.\1\ --------------------------------------------------------------------------- \1\ IQVIA Institute for Human Data Science. ``Medicine use and spending in the U.S.: A review of 2017 and outlook to 2022.'' https:// www.iqvia.com/institute/reports/medicine-use-and-spending-in-the-us- review-of-2017-outlook-to-2022. Published April 19, 2018. Accessed April 2018. However, we share the concerns expressed by FDA Commissioner Gottlieb regarding the challenges biosimilars have experienced in penetrating the market. Merck introduced a biosimilar to the market 18 months ago at a 35 percent discount to the originator product, yet we have captured only a tiny fraction of the market. In general, biosimilars competition thus far has resulted in moderation of prices, but actual utilization of the biosimilars remains modest at best. We fear that an environment where market entry of biosimilars brings value to the market, but little or none of that value accrues to the --------------------------------------------------------------------------- biosimilar, will not be sustainable. Therefore, we urge Congress to pursue policies to encourage and support biosimilar uptake and utilization in order to realize these potential savings for the system and patients. These could include reduced cost sharing in Medicare Part B. Fourth, we believe that prices can more align with a drug's value when manufacturers and payers are able to negotiate innovative contracts that base payment on a drug's benefits. Manufacturers should be rewarded based on the value that our therapies deliver. When we developed our breakthrough immuno-oncology treatment Keytruda, we incorporated a biomarker where clinically appropriate so that we could identify those patients most likely to benefit, but this is not always the case. We did this because we believe in giving the right medicine to the right patient at the right time. This is important both for therapeutic and economic reasons. If patients regularly take our medicines as they are prescribed, we are prepared to stand behind their effectiveness. Moving to a system where we are reimbursed for the value our medicines provide would be revolutionary. Yet there remain major regulatory and operational obstacles to value-based payment and contracting in the commercial and public markets, which we urge Congress to address. Fifth, we support efforts to encourage generic competition. A version of Chairman Grassley's CREATES Act could make some needed reforms to encourage generic competition, and there are likely other policies we should consider as well to ensure there is no inappropriate gaming of the system. We also support the idea of eliminating the use of drug company coupons in cases where a brand name drug now has generic competition. This slows the use of generics and violates the spirit of the Hatch- Waxman drug price competition law. Finally, we would also like to work with the committee to find ways to end the price gouging pursued by those who jack up the prices of off-patent drugs that have no competition. These high prices hurt patients and do not create incentives for the kind of cutting edge research we pursue. These six changes could bring real relief to patients while preserving the incentives that allow us to invest billions in developing new medicines. These are exciting times, when decades of investment in scientific research are yielding life-changing discoveries. But it is the investment of today that fuels the innovations of tomorrow, and if we damage the ecosystem that drives those investments, we'll never know what we could have achieved for the patients we are all here to serve. The single most important contribution that we make at Merck--to economies, to health care, and to individual patients and their families--is to continue making the necessary costly and long-term investments in R&D and persuading thousands of brilliant researchers to sit at a lab bench and try to create something transformative--despite the overwhelming odds that their efforts will not succeed, since 9 out of 10 compounds that even start clinical trials will fail. The solutions to health-care spending and out-of-pocket costs for patients must be achieved in a way that provides the balance necessary for innovation to occur. The innovation ecosystem includes academia, small biotechnology companies, large pharmaceutical companies, government, and patients and providers. It is incumbent on all of us to solve the affordability challenges of today's patients without compromising our ability to invent for tomorrow's patients. I'd like to end on a personal note. My mother died when I was a child and my siblings and I were raised by my dad who worked as a janitor in North Philadelphia. He was a giant in my life and it was devastating when Alzheimer's took him away from me and my family. Last year, after spending many years and over a billion dollars, Merck had to end development of a promising new Alzheimer's therapy because it simply didn't work. Yet we continue on, seeking better approaches. And I truly believe Merck or one of the other companies at this table can and will find a medicine that will ensure that no one will have to experience the pain of seeing a loved one taken from them in this way. But, our success depends on having a U.S. market that is free, competitive, and predictable. The changes I've discussed today have the potential to vastly improve that market and help patients survive and thrive without financial hardship. I am here to pledge our cooperation with you for creating such changes. Thank you. ______ Questions Submitted for the Record to Kenneth C. Frazier Questions Submitted by Hon. Chuck Grassley Question. At the hearing, you testified that Merck does not withhold samples from generic manufacturers in order to block generic versions of your drug from entering the market. You also expressed your support for the ``Creating and Restoring Equal Access to Equivalent Samples Act,'' also known as the CREATES Act. However, the FDA has a list on its website which identifies reference listed drug (RLD) access inquiries where brand manufacturers may have prevented generic companies from obtaining samples of products necessary to support FDA approval. Cubist Pharmaceuticals is on this FDA list. According to news reports, Merck bought this company in 2014. If this is accurate, this would appear to contradict your testimony at the hearing that Merck has not withheld samples of their products to delay generic competition. Could you please explain in detail the discrepancy between your testimony and the FDA list? Has Merck ever blocked access to samples? Answer. Merck does not block generic companies from accessing samples. Your inquiry references FDA's website for reference listed drugs, or RLDs, which lists inquiries the agency has received from potential generic companies for samples of RLDs. Importantly, FDA's website also provides the following statement in describing the various inquiries related to the RLDs listed: ``We note that FDA has not independently investigated or confirmed the access limitations described in the inquiries received.'' As FDA's website details, ENTEREG (alvimopan) has a restricted distribution requirement mandated by its FDA-approved Risk Evaluation and Mitigation Strategy (REMS). ENTEREG is the only Merck product subject to an FDA-approved REMS. Under this program, ENTEREG is available only to hospitals that perform surgeries that include a bowel resection and dispensed by pharmacies that are enrolled in the E.A.S.E. ENTEREG REMS Program. This program is designed to ensure that ENTEREG is used in accordance with the FDA-approved label. Merck acquired ENTEREG from Cubist Pharmaceuticals in 2015. Since acquiring ENTEREG, whenever Merck has received a request from a generics company to supply ENTEREG, we have directed them to the draft FDA Guidance which outlines how the generics company can obtain a letter from FDA stating that their study protocols contain the appropriate safety protections for products subject to this type of REMS. If provided with a copy of such a letter from FDA, Merck is happy to work with generics companies on supply arrangements. To date, we have not received any such letters. FDA's website also details that the agency has not issued any Safety Determination Letters for samples of ENTEREG. Question. The Department of Health and Human Services' proposed rule, ``Fraud and Abuse; Removal of Safe Harbor Protection for Rebates Involving Prescription Pharmaceuticals and Creation of New Safe Harbor Protection for Certain Point-of-Sale Reductions in Price on Prescription Pharmaceuticals and Certain Pharmacy Benefit Manager Service Fees,'' envisions that drug manufacturers will offer up-front discounts rather than the back-end rebates that are now commonly provided. Some observers argue that a 1996 court case called into question whether manufacturers could offer up-front discounts, resulting in today's rebate-based system. I've heard differing opinions as to whether the issues related to the initial court case are still relevant. If the HHS proposed rule is finalized, can you assure the committee that your company will offer up-front discounts? If not, why? Answer. Merck is aware that some in the industry have asked whether the antitrust laws as interpreted in the In re Brand Name Prescription Drugs Antitrust Litigation would limit the ability of manufacturers to offer point-of-sale discounts (as opposed to rebates). But, the U.S. antitrust laws, including the Robinson-Patman Act, apply to price discrimination in any context (including rebates), and nothing about In re Brand Name Prescription Drugs Antitrust Litigation changes this fact. As a result, Merck commits that, if the OIG's Proposed Rule is finalized, we will modify our contracts to comply with the new safe harbors and will provide discounts in a manner consistent with the new regulations. Question. Please describe how you expect your company to respond to the HHS proposed rule to eliminate safe harbor protection for back-end rebates in Medicare Part D that is referenced above if it is finalized. Assuming you are confident that antitrust laws do not prevent your company from offering up-front discounts, specifically, do you envision that your company lowers the list price of a drug to the current after- rebate net price, offer discounts equal to the current rebate amount, or a combination of both? Answer. We expect that the robust negotiations that occur today will continue in the highly competitive Part D market, and we expect to realize the same level of net price that we do today. In fact, we expect that there could be additional pricing pressure under the new system, which could lead to lower net prices. Over time, we expect that our list prices will go down if the misaligned incentives across the system are addressed. We are currently working with other stakeholders in the system to solve the operational challenges that will enable these changes. But, it is also important to note that if the rule is implemented, Medicare beneficiaries' out-of-pocket costs will be reduced, independent of any lowering of list prices, since their cost-sharing will be based on the net price. Nonetheless, we believe the rebate rule will align incentives in a way that will restrain list prices. If this rule is implemented as written, it would only apply to our contracts with PBMs and health plans for Medicare Part D and Managed Medicaid. If PBMs and health plans maintain the rebate model in the commercial market, we would still have commercial contracts based on rebates, which would be subject to the existing constraints to lowering list price. We also would still need a mechanism to revalue drug in the distribution channel in a financially viable manner. Question. To what extent are the back-end rebates your company currently offers contingent on the amount of market share realized for your drugs as a result of Part D plan formulary placement and other techniques? Answer. Our contracts typically provide rebates to Part D plans in exchange for a specified formulary status. We are aware of only one current agreement that makes a Part D rebate contingent on reaching a certain market share. Question. Please provide a breakdown of percentage of sales that go to each payer (including Medicare, Medicaid, private pay, other) and a similar percentage by volume of the total number of each drug compared to total volume. Please provide this data for the most recent year available. Answer. The table below provides a proxy for volume by reporting percentages based on gross sales from 2018, given that there is no standard unit of volume measure that can be applied across our diverse product line (e.g., tablet products, injectable products, vaccines). ------------------------------------------------------------------------ Segment Gross/Volume ------------------------------------------------------------------------ CML+Specialty Pharm 28% ------------------------------------------------------------------------ Hospital / GPO / 340B 23% ------------------------------------------------------------------------ Medicare Part D 19% ------------------------------------------------------------------------ Medicare Part B 12% ------------------------------------------------------------------------ Medicaid 12% ------------------------------------------------------------------------ Federal 6% ------------------------------------------------------------------------ Notes: CML refers to private commercial payers; Medicare Part B also encompasses Part B products sold through Medicare Advantage Plans; Medicaid includes fee for service and managed Medicaid; Federal includes the VA, DoD, Coast Guard, Public Health Service and other similar purchasers. Question. Do your companies hire consultants or lobbyists to promote products at State Medicaid Pharmacy and Therapeutics Committees? Answer. No. While Merck does contract with lobbyists who may interact with individuals associated with State Medicaid programs, they do not promote products at State Pharmacy and Therapeutics Committees. Question. To whom do you disclose advocacy activities surrounding State Medicaid programs, if at all? Answer. Merck requires employees to adhere to State ethics law requirements for disclosing advocacy activity. Additionally, employees who attend Medicaid program meetings must comply with State public meeting law requirements pertaining to their attendance and participation. Question. Please describe how the costs of patient assistance programs are accounted for within your company's financial statements. Please also describe the types of market information, such as prescribing and use patterns, that your company collects from different types of patient assistance programs and patient hub services. Answer. For purposes of this question, we are interpreting ``patient assistance programs'' to include the Merck Patient Assistance Program (Merck PAP), which provides free product to qualifying patients, Merck donations to independent patient assistance foundations, and Merck's patient coupon programs which help eligible privately insured patients afford their prescribed medications. Merck also makes available patient hub support programs to assist patients with accessing their prescribed medications. With respect to the company's financial statements, for Merck PAP and Merck's donations to independent patient assistance foundations, the costs are recorded to the ``Selling, general and administrative'' category on our Consolidated Statement of Income. The co-pay assistance made available to patients through Merck's coupon programs is treated as a reduction to Merck's gross sales for the applicable products and is included in the ``Sales'' line of our Consolidated Statement of Income. The expenses associated with administering Merck's coupon programs are recorded in the ``Selling, general and administrative'' category on our Consolidated Statement of Income. Similarly, the expenses associated with administering Merck's patient hub support programs are recorded in the ``Selling, general and administrative'' category of our Consolidated Statement of Income. Merck receives different types of market information in connection with the different programs identified above. For market information associated with the Merck PAP, the Merck PAP reviews data, such as patient insurance status and household income, to determine an individual's eligibility for PAP program enrollment. Merck PAP also tracks the number of prescriptions associated with the PAP for budgeting and planning purposes, but Merck PAP does not collect information associated with the courses of therapy for individual patients. With respect to Merck's donations to independent patient assistance foundations Merck does not receive any market information. Merck receives only a final report that confirms donations were received and spent in their totality for their intended purpose. With respect to Merck's patient coupon programs, Merck may receive certain market information to assist it with evaluating whether its coupons programs are functioning consistent with their intended purpose and whether the vendor is meeting its contractual obligations. The information also may be used to assist Merck with budgeting and planning. For example, Merck may receive information about: the product filled; the product dispensing date and site; the prescriber; the number of patients enrolled in the coupon program; the number of coupons redeemed; the patient out-of-pocket costs associated with the use of a Merck coupon; and the benefit amount Merck pays on behalf of privately-insured patients using a coupon. With respect to Merck's patient hub support programs, Merck may receive certain market information to assist it with evaluating whether its hub support programs are functioning consistent with their intended purpose and whether the vendor is meeting its contractual obligations. The information also may be used to assist Merck with budgeting and planning. For example, Merck may receive aggregate information about: call type, frequency, and vendor response times; the number of patients enrolled in the program; patient enrollment demographic and diagnosis information; patient benefit investigations; insurance coverage information for the applicable product; and pharmacy product fulfillment information. Merck's third-party contractors may receive additional, patient- specific information that is not shared directly with Merck. Question. Please provide a list of all contributions since January 1, 2014, that your company has made to any tax-exempt organizations working on issues related to drugs within your product lines, including but not limited to patient groups, disease awareness groups, medical or professional societies, universities or hospitals, industry associations or leagues. For each contribution, please provide the name of the organization that received the donation, the date the donation was made, the amount of the donation, and a description of the purpose of the contribution (i.e., was the contribution for the general fund, a specific purpose to a specific program, or continuing medical education). Please also note whether the contribution was unrestricted or restricted; if it was restricted, please explain all restrictions. Finally, if your company maintains a foundation or other separate charitable arm, please provide the name of all such entities, and list all donations made from that entity or entities. Answer. The information concerning our Philanthropic grants and charitable contributions, including contributions made through the Office of Corporate Responsibility, our company's Foundation, U.S. Global Human Health, and the MSD for Mothers Program can be found here: https://www.msdresponsibility.com/ethics-transparency/transparency- disclosures/. Please note the website does not include grants or contributions from Merck's Research Laboratories or Merck's Manufacturing Division. In addition, the information concerning our grants of more than $500 provided by the company's Global Human Health division to U.S. organizations in support of independent, accredited educational programs for health-care professionals, as well as grants to patient organizations and other medical education or scientific societies and organizations in the United States, Europe, the Middle East, Africa and Canada can also be found at the website referenced above. Question. Pay for delay agreements cost consumers and taxpayers billions in higher drug costs every year. The FTC has gone after drug companies that enter into these settlements where the brand pays the generic company to keep its lower cost alternative off the market. I'm the lead Republican sponsor of S. 64, the Preserve Access to Affordable Generics and Biosimilars Act, which would help put an end to these deals. Do you agree that these pay-off agreements keep drug costs high for patients because they delay competition? Answer. Patent settlement agreements challenged by the FTC as anti- competitive, in which brands pay generic companies to stay out of the market when it would otherwise be lawful for them to enter the market, could delay patient access to lower cost alternatives. In contrast, patent settlement agreements in which the brand, while not conceding the invalidity or non-infringement of the patents, but in the face of the uncertainties and costs associated with protracted litigation, settles cases in a manner that allows a generic to enter the market prior to expiry of the brand's patents could actually accelerate patient access to lower cost alternatives. Still, brands do not enter into such agreements lightly because they believe in the rights of patent holders to vigorously enforce their intellectual property rights in court. At the end of the day, these settlements do not delay entry or cause the loss of any lawful competition because entry prior to the expiry of these patents would be unlawful infringement unless and until the generic manufacturers prevailed in court. Question. Has your company ever entered into these kinds of settlements with a generic company? Answer. Merck has not entered into patent settlement agreements with generic companies to delay their entry past when it would otherwise be lawful for them to enter the market. Merck has been party to a number of patent settlement agreements that provide for generic market entry prior to patent expiry, including some that have provided some level of exclusivity for a limited time. These agreements allowed generic products to enter the market earlier than would have otherwise been the case. The FTC has not challenged as anti-competitive any of these types of agreements involving Merck. Question. Do you support the pay for delay bill? Answer. Merck does not support S. 64 in its present form. Merck believes that the development of the law through the judicial process is the most effective way to address the balance between antitrust law and patent law raised by settlement agreements. S. 64 upsets the careful balance embodied in a rule-of-reason analysis by creating a presumption that ``anything of value'' or an ``exclusive license'' are anticompetitive, thus denying an antitrust defendant the ability to present and rely on countervailing evidence of pro-competitive effects, such as the impact on competition by the entry of the generic product before the expiration of the patent or statutory exclusivity term. As noted by the Supreme Court in FTC v. Actavis: Given these factors, it would be incongruous to determine antitrust legality by measuring the settlement's anticompetitive effects solely against patent law policy, rather than by measuring them against procompetitive antitrust policies as well.\1\ --------------------------------------------------------------------------- \1\ FTC v. Actavis, 570 U.S. 136, 148 (2013). S. 64 also seeks to insulate the FTC's fact finding from judicial review. Finally, the retroactive application of the provisions of the bill to June 2013 is unworkable. While there had been a split between the Circuit Courts over the proper analysis of reverse payment settlements, the Supreme Court's opinion in Actavis in 2013 settled that split by holding that patent settlements including those with reverse payments were subject to a rule-of-reason analysis. That decision did not provide hard and fast rules for the balance between antitrust and patent principles. To impose a process that alters that balance, and to do so retroactively, is imprudent and unfair. rebate traps/walls Question. I'm increasingly concerned about the effect of so-called ``rebate traps'' or ``rebate walls'' on patients' access to quality, lower cost medicine. I understand there is ongoing litigation challenging these practices as anti-competitive. Does your company engage in the bundling of rebates over multiple products? If so, why? And what benefit does the consumer gain from that? Answer. Merck understands this question to refer to certain concerns about contracting practices applied to contracts between manufacturers and PBMs or health plans. Merck offers rebates to payers on bundles of products within certain product families (e.g., JANUVIA and JANUMET, ASMANEX TWISTHALER and ASMANEX HFA). These bundled discounts benefit patients by ensuring that multiple therapies are maintained on a PBM or health plan formulary, thus ensuring wider patient access to our medicines at lower costs to the payer. Merck also offers discounts with respect to multiple bundled products outside of the PBM and health plan contracts, such as in the vaccine and hospital markets. Question. Does your company view these practices as anticompetitive or harmful to patients' access to quality, lower cost medicine? Answer. No. Merck believes the rebates it offers to payers on pharmaceutical products are procompetitive. Merck does not believe that its rebating practices are harmful to patients. Question. If a policy were adopted to eliminate rebates, or to require that rebate savings be passed on to the consumer, would that in and of itself solve the issue of rebate ``traps'' and ``walls''? And would consumers benefit from such a policy? Answer. Merck is very supportive of current efforts to change the system. We believe these efforts will remove misaligned incentives within the system, drive more transparency in the system and, most importantly, benefit patients by lowering out-of-pocket costs. It is difficult to predict whether these changes will solve all of the issues seen today, but Merck is committed to working toward additional solutions if issues remain after these changes are implemented. drug pricing Question. When setting the list price of a drug, does your company consider regulatory costs or compliance? If so, how specifically do those factors affect the list price of a drug? Please provide at least one specific example, if applicable, from your current product portfolio. When setting the list price of a drug, does your company consider the risk of liability or litigation? If so, how specifically do those factors affect the list price of a drug? Please provide at least one specific example, if applicable, from your current product portfolio. Answer. In setting the list price for a drug, we do not specifically consider the regulatory costs or compliance or the risk of liability or litigation. Merck approaches pricing from the perspective of value. This approach looks at the value that a medicine provides through multiple lenses with the goal of reflecting its benefit to patients and to society, while at the same time paying an appropriate return on invested capital to our investors, to ensure that we are able to sustain R&D. While each individual situation varies based on factual circumstances and market dynamics, generally, we consider: Value provided to patients--to what extent does a new medicine or vaccine establish a new standard of care that has the potential to significantly extend and improve patient lives? Value provided to health-care systems--to what extent does a new medicine or vaccine reduce the costs associated with hospitalization and other costly complications of disease if not appropriately (or optimally) treated? Unmet need--does a new medicine or vaccine address a critically unmet medical need, where few or no treatments exist? Access--what is the ability of various customers around the world--including national, regional or local institutional payers, physicians, employers and patients--to pay for our products? R&D sustainability--given the long-term risk and cost of capital, can we appropriately compensate our investors to ensure continued investment in the kind of risky and capital- intensive research and development that will bring forward medically important breakthroughs? Competition--what are the costs of other treatments currently on the market relative to the value provided by Merck's products? ______ Questions Submitted by Hon. Pat Roberts Question. What role do you see value-based arrangements (VBAs) playing in the effort to reduce prescription drug costs? What potential do these arrangements have to find the ``sweet spot'' between controlling costs to patients and encouraging innovation of new drugs? How can VBAs help lower what patients pay out-of-pocket? Can Congress do more to allow for and encourage the use of VBAs? Answer. For more than 10 years, Merck has worked with payers and health-care providers to advance alternative pricing and contracting arrangements, and Merck has publicly shared information about value- based agreements (VBAs) it entered into with the payers Aetna and Cigna. We are continuously reviewing ways in which the company may enter into VBAs for our products, which we define as a contractual framework aimed at achieving a mutually agreed upon value objective that that drives greater value from health care spending. Merck is interested, where business and customer objectives align, to implement VBAs across the health care market, including Medicare Part D, Managed Medicaid, and Fee-For-Service Medicaid. By aligning payments for medicines more directly with their value in improving meaningful health outcomes and/or reducing the need for other health-care services (such as hospitalizations), VBAs make pharmaceutical manufacturers accountable for the results their products achieve in a concrete way and can help improve patients' health and maximize the benefits of health-care spending. A recent Avalere survey of payers found that 44 percent of payers engaged in outcomes-based contracts experienced improvements in patient outcomes.\2\ --------------------------------------------------------------------------- \2\ Avalere Health. ``Outcomes-Based Contracts: Payer Perspectives.'' Avalere Policy 360. July 19, 2018. VBAs also can increase patient access to new therapies which could ultimately improve patient outcomes. A payer that might otherwise decline to cover a new medicine (or that would only cover the medicine with significant utilization management restrictions or high cost sharing) due to uncertainties about the expected percentage of its patient population who would benefit might increase access to the medicine if the manufacturer shared the risks of the medicine's performance. These agreements may make medicines more accessible to patients who will benefit from them and increase competition in relevant therapeutic classes.\3\ Researchers have found that value- based arrangements can improve patient access to medicines.\4\ --------------------------------------------------------------------------- \3\ Staley, L. ``A Drug's Worth: Why Federal Law Makes It Hard to Pay for Pharmaceutical Performance.'' Boston University Law Review. 2018;98(1):303-334. (``Tying reimbursement to health outcomes presents new opportunities for competition with rival manufacturers. . . . [A] manufacturer that can demonstrate sustained health benefits in post- market studies may distinguish itself from competitors.''). \4\ See, for example, description of Entresto and Repatha contracts in: Seely, E., and Kesselheim, A. ``Outcomes-Based Pharmaceutical Contracts: An Answer to High U.S. Drug Spending?'' Commonwealth Fund. Issue Brief. September 2017. While Merck has had some experience with VBAs, these efforts have not been as robust as they could be due to the challenges involved in developing and implementing them. In addition to infrastructure and data limitations, challenges include regulatory limitations such as government pricing frameworks (e.g., Medicaid Best Price (BP) rules, --------------------------------------------------------------------------- Medicare's Average Sales Price (ASP)) and Federal fraud and abuse laws. Accordingly, we support opportunities that would enable greater experimentation in the design, structure, and implementation of VBAs. Further innovation in this space is needed to support overall sponsor and plan learning, and to determine the range of potential benefits to diverse health systems and beneficiaries. To fully achieve these goals, however, the impacts of the current regulatory framework, including government pricing requirements, the Federal Anti-Kickback Statute (AKS), and overall environmental barriers, must be analyzed and addressed as appropriate. Policy solutions such as the Patient Affordability Value and Efficiency Act (PAVE), introduced by Senators Warner and Cassidy, could provide necessary regulatory flexibility for properly structured VBAs. ______ Questions Submitted by Hon. Michael B. Enzi Question. More than 10 years ago, I worked on a bipartisan basis with my good friends Ted Kennedy and Orrin Hatch to develop a biosimilars approval pathway. One of the difficult things was accounting for the differences between biosimilars and generics. I have said before that if a drug was a three-bedroom, two-bath home, a biologic would be a skyscraper. The size and complexity of the items are just that different. I understand that it is much harder to build a skyscraper without blueprints than a house. Even though the science has come a long way since then, there aren't as many biosimilars on the market as we might have hoped. Do you think the incentives in the law appropriately account for the differences between biosimilars and generics? Answer. In general, biosimilars competition thus far has resulted in moderation of prices, but actual utilization of the biosimilars remains modest at best. We fear that an environment where market entry of biosimilars brings value to the market, but little or none of that value accrues to the biosimilar patient or the health-care system, will not be sustainable. Merck remains an advocate for rigorous biosimilarity standards globally, and we believe that all biosimilar product applicants should be required to demonstrate equivalence (i.e., biosimilarity) in safety (including immunogenicity) and efficacy, and no differences in purity and potency profiles between the originator reference product and the biosimilar candidate. We believe the FDA has instituted such a standard with its Totality of the Evidence approach, ``including structural and functional characterization, nonclinical evaluation, human PK and PD data, clinical immunogenicity data, and comparative clinical study(ies) data.'' \5\ --------------------------------------------------------------------------- \5\ U.S. Food and Drug Administration. ``Scientific Considerations in Demonstrating Biosimilarity to a Reference Product Guidance for Industry.'' (Apr. 2015), https://www.fda.gov/downloads/drugs/guidances/ ucm291128.pdf. We are urging Congress to pursue policies to encourage and support biosimilar uptake and utilization in order to realize these potential savings for the system and patients. These policies could include --------------------------------------------------------------------------- reduced cost sharing in Medicare Part B. Question. I know there are proposals to essentially pay more for biosimilars to make them more attractive, but that is not exactly what we were intending when we wrote the law. Can you talk about adverse incentives in the market and any barriers to market penetration that we might address to help improve patient access to these lower cost products? Answer. Merck introduced a biosimilar to the market 18 months ago at a 35- percent discount to the originator product, yet we have captured only a tiny fraction of the market. Uptake of the product was limited, we believe due to physician confusion regarding interchangeability and extrapolation, and a lack of physician, patient, and payer incentives. While we believe that the prescribing physician must always have the authority to designate exactly which biological product is dispensed to the patient, we believe there are market barriers that hamper appropriate adoption of biosimilars. Merck encountered the following market barriers that hampered uptake of RENFLEXIS: We have observed cases where Medicare Advantage plans seem to be imposing utilization management controls that require providers to first use the reference biologic before providing coverage for the biosimilar. This is a significant disincentive to biosimilar uptake in that setting, and we believe is contrary to policy objectives to promote the uptake of biosimilars. Some providers may be hesitant to adopt biosimilar products due to overall confusion and the current lack of standardized definitions of biosimilarity (including the concepts of extrapolation and interchangeability). Currently, we lack standardized definitions of interchangeability as it relates to clinical significance, and concerns about the clinical appropriateness of switching stable patients to a biosimilar product have been contentious issues for some prescribers. Further, prescribers may be comfortable with a single switch (i.e., moving a stable patient from a reference product treatment protocol to a biosimilar), but may have concerns about switching a patient multiple times, absent the interchangeability designation. We believe that regulatory clarification of these terms and concepts could help mitigate concerns for providers and support biosimilar product adoption. We suggest the following policy changes to help encourage and support prescriber biosimilar utilization: Consider options to reduce or eliminate patient cost sharing in Medicare Part B for biosimilars. While some Part B beneficiaries are already able to reduce their 20 percent cost sharing via supplemental coverage, we believe eliminating cost sharing will encourage many physicians to use biosimilars for their patients. A similar approach in Part D and in Medicaid for small-molecule generics has driven generic utilization up to 90 percent.\6\ --------------------------------------------------------------------------- \6\ Department of Health and Human Services. Office of Inspector General. ``Generic Drug Utilization in the Medicare Part D Program.'' (Nov. 2007), https://oig.hhs.gov/oei/reports/oei-05-07-00130.pdf. Create pathways for MA and Part D plans to receive bonus payments and/or enhanced star ratings for achieving metrics related to access to biosimilars. This will incentivize plans to implement policies that drive additional utilization of --------------------------------------------------------------------------- biosimilars. Consider alternative reimbursement methodologies that adjust the current Part B reimbursement formula. The current structure in Part B to reimburse at ASP + 6 percent of the reference product's ASP ensures there is no reimbursement downside to physicians for using biosimilars. But so far, the evidence does not suggest the current reimbursement rate sufficiently incentivizes providers to use biosimilar products. Congress should consider alternatives to further incentivize physician adoption of biosimilars. ______ Questions Submitted by Hon. John Cornyn Question. We continue to hear that rebates negotiated off of the list price of a drug are both good and bad. Pharmacy benefit managers and plans have argued that rebates are used to lower premiums across the board and that it is the best way to seek a price concession on otherwise expensive drugs. Your industry argues that these payers are insisting on higher rebates that can only be achieved by raising list prices. But patients often lose under this system, with out of pocket costs being tied to list price. Insulin patients appear to be routinely impacted by this perversity in the system. Please explain to the committee how your company would reduce list prices if rebates were no longer a part of the equation? What assurance can you provide that you would in fact lower your prices? What actions should be taken to ensure that patients are actually seeing the benefits of lower out of pocket costs? Answer. As we stated when we reduced the list price of several of our products in July 2018, we will continue to look for opportunities to reduce our list prices. We think the proposed rule will help create those opportunities, but it can't happen overnight. We are currently working with other stakeholders in the system to solve the operational challenges that will enable these changes. It is important to note that if the proposed rule is implemented, Medicare beneficiaries' out-of-pocket costs will be reduced, independent of any lowering of list prices, since their cost-sharing will be based on the net price. Further actions to ensure patients actually see the benefit of lower out of pocket costs might include prohibitions on changes in benefit design by payers/PBMs that could allow payers/PBMs to defeat the intent of delivering savings to patients. Question. If rebates are driving high list prices for drugs as drug manufacturers' claim, why do you think that Part B drugs, which have no PBM rebates, are also seeing significant price increases? Whose fault is that? Answer. While the misaligned incentives of Part D are partly responsible for PBMs favoring high list prices, that is not the sole dynamic associated with price increases. There may be unique reasons for price increases on specific products given their individual circumstances, including competitive dynamics and the costs of clinical research and manufacturing improvements. In addition, while PBMs generally do not manage Part B benefits, this does not mean that discounts are not provided or applied on these products. Providers and commercial health plans do receive discounts, the average of which is passed along to patients through ASP-based reimbursement. The 20-percent coinsurance paid by a patient is based on the ASP, which reflects the average discounts received by providers and payers. biosimilar competition/insulin Question. Biosimilars have been much anticipated as a solution to the drug pricing crisis. In particular, the FDA is moving to make insulin a biologic that would be subject to biosimilar competition in the future. But we are hearing from all of you that the biosimilar market doesn't work and the benefit of these cheaper but equally effective alternatives are really not available to U.S. patients. Can a biosimilar version of insulin be part of the solution for diabetes patients? If so, what changes need to be made to the system so that patients and the taxpayer can realize the benefit of biosimilars? (Merck gave up on pursuing a biosimilar to Sanofi's Lantus \7\) --------------------------------------------------------------------------- \7\ Arlene Weintraub. ``Merck Ditches Biosimilar Lantus, But Will That Ease the Path for Mylan's Rival Insulin Product?'' FiercePharma. (Oct. 12, 2018), https://www.fiercepharma.com/pharma/merck-ditches- biosimilar-lantus-but-will-ease-path-for-mylan-s-rival-insulin-product. Answer. We believe there is potential for significant savings to national health-care systems if high quality biosimilars--including insulins--can be brought to the market and compete with those biologics --------------------------------------------------------------------------- that have exhausted their intellectual property protections. Biosimilar products are still the subject of a great deal of confusion, particularly among providers, regarding the scientific, regulatory, and clinical basis for extrapolation and interchangeability decisions made by the FDA. Merck has urged the FDA to expand its work in educating providers and other stakeholders on these topics. Beyond that, we believe Congress should consider policy changes to help encourage and support prescriber biosimilar utilization. In our Blueprint comments to HHS we recommended incentives targeting patients, health plans, and providers that we believe can move the needle in stimulating uptake. One idea is for Congress to consider options to reduce or eliminate patient cost sharing in Medicare Part B for biosimilars. As to the Lantus biosimilar, after a comprehensive assessment of the current and future market environment for insulin glargine, including biosimilars, which included an assessment of anticipated pricing and cost of production, we made the business decision to terminate our agreement on the commercialization of the Lusduna pen and vial. There is already one other biosimilar glargine on the market and others on the way. So, we concluded this space was, or soon will be, adequately covered. This will allow us to allocate resources to other products in development. ______ Questions Submitted by Hon. Todd Young re-evaluating business strategies in foreign countries Question. Since taking office, President Trump has made reducing drug prices one of his highest priorities--and has repeatedly spoken about his frustration with the U.S. subsidizing the costs of pharmaceuticals for the rest of the world. He has gone so far as to issue proposals, like the International Pricing Index (IPI) Model, in an attempt to bring down prescription drug prices. With the increased scrutiny of the industry and of the drug supply chain as a whole in the United States, have any of your companies re- evaluated your business strategy in foreign countries? If not, then why? If a proposal, like IPI, were implemented, would it force your companies to potentially ``walk away from the negotiating table when other countries demand low prices subsidized by America's seniors,'' as HHS Senior Advisor for Drug Pricing Reform John O'Brien has said? What are some of your ideas on how we can ensure Americans aren't shouldering the full cost of pharmaceuticals? Answer. Merck continually reevaluates its business strategies in all markets, seeking in particular to make its vaccines and medicines accessible to patients while realizing their full value in foreign markets with regulatory schemes that do not recognize the full value of these products and artificially reduce prices. Nevertheless, in most markets there are very limited options for adjusting prices to recognize the full value of our medicines and vaccines. One-sided and onerous pricing and reimbursement schemes most often leave little room for negotiation. With regard to ``walking away from the negotiating table,'' Merck always reserves that option. However, we recognize the serious and negative implications on patient health and access, the company's ultimate mission, and other possible repercussions that would result from denying patient access to our medicines. Moreover, foreign governments can resort to compulsory licensing, essentially seizing patent rights, where a company refuses to market a product, which also makes it difficult to withdraw from a foreign market. Regarding ideas to ensure Americans aren't shouldering the full cost of pharmaceuticals, we believe appropriate U.S. trade strategies are a promising avenue to dealing with unreasonable foreign government action. Positive actions in the U.S. can also reduce prices in the U.S., including removing misaligned incentives that cause PBMs to favor more expensive products and lead to higher out-of-pocket costs for U.S. patients, like the administration's proposal regarding the rebate safe harbor. One potential proposal would be to create a special USTR negotiator specifically for drug pricing issues. foreign countries' pricing and reimbursement Question. President Trump and Secretary Azar have both repeatedly described their frustrations with ``foreign freeloading'' of U.S. drugs in the last year. ``When foreign governments extort unreasonably low prices from U.S. drug makers, Americans have to pay more to subsidize the enormous cost of research and development. . . . It's unfair and it's ridiculous, and it's not going to happen any longer.'' Do you agree that because of foreign countries' pricing and reimbursement systems, U.S. patients and innovators are shouldering the burden for financing medical advances? How do foreign countries' pricing and reimbursement systems affect our prescription drug costs? Are foreign governments taking note of the concerns being raised by the Trump administration and have they responded in any way? Has there been any noticeable change in any of our trade agreements since these concerns have been raised by the Trump administration? Answer. We agree that foreign countries' pricing and reimbursement systems result in their not paying enough to support the biopharmaceutical innovation from which they benefit. This causes the U.S. to shoulder more than its fair share of financing medical advances. These pricing and reimbursement systems do not necessarily, however, affect prescription drug costs in the U.S. in any direct or algorithmic fashion. Rather, Merck approaches pricing from the perspective of value. This approach looks at the value that a medicine provides through multiple lenses with the goal of reflecting its benefit to patients and to society, while at the same time paying an appropriate return on invested capital to our investors, to ensure that we are able to sustain R&D. While each individual situation varies based on factual circumstances and market dynamics, generally, we consider: Value provided to patients--to what extent does a new medicine or vaccine establish a new standard of care that has the potential to significantly extend and improve patient lives? Value provided to health-care systems--to what extent does a new medicine or vaccine reduce the costs associated with hospitalization and other costly complications of disease if not appropriately (or optimally) treated? Unmet need--does a new medicine or vaccine address a critically unmet medical need, where few or no treatments exist? Access--what is the ability of various customers around the world--including national, regional or local institutional payers, physicians, employers and patients--to pay for our products? R&D sustainability--given the long-term risk and cost of capital, can we appropriately compensate our investors to ensure continued investment in the kind of risky and capital- intensive research and development that will bring forward medically important breakthroughs? Competition--what are the costs of other treatments currently on the market relative to the value provided by Merck's products? Prices in other countries often reflect different value systems and criteria. It is important to note that all components of the health care system, including hospital services, physician services, physician salaries, and medical devices are considerably less expensive in foreign countries than in the U.S. That said, we agree that foreign countries' pricing and reimbursement systems result in their not sufficiently supporting biopharmaceutical innovation. While foreign governments are generally aware of concerns raised by the Trump administration, we are not aware of any substantive response. There has been some change in trade agreements, but more work needs to be done. U.S. free trade agreements address discriminatory approaches to pricing and reimbursement and ensure fair treatment for innovative medicines through commitments established by trade partners. Free trade agreements can help advance innovation, versus approaches proposed by the administration such as the International Pricing Index that have the potential to stifle investment in R&D by driving down prices across markets. Here are three examples: A 2004 U.S. Department of Commerce study examining OECD countries found that foreign price controls restrict the ability to innovate in our sector and identified trade agreements as a key lever. We strongly encourage the Trump administration to update this report to reflect the impact of continued price controls in OECD countries. The pharmaceutical pricing and reimbursement provisions in the U.S.- Mexico-Canada Agreement commit governments to provide transparency and due process protections in national pharmaceutical reimbursement processes and decisions. This is a step in the right direction, but more is needed to ensure that many countries, such as Canada, appropriately recognize the value of innovative medicines. The Trump administration has worked to ensure adherence to commitments in pricing and reimbursement in the Korea-U.S. Free Trade Agreement, and direct advocacy by the U.S. has also made an impact in Japan to mitigate some approaches. There is clearly more work to be done in these areas, and trade tools such as a new U.S.-Japan Free Trade Agreement, are critical. medicaid closed formulary proposals Question. In an attempt to bring down drug costs, various States have been exploring whether to exclude certain drugs from its Medicaid program. For example, the State of Massachusetts' recently asked CMS for permission to create a closed formulary where the State Medicaid program would pick at least one drug per therapeutic class. CMS denied their waiver request citing violation of Federal law, but this proposal does bring up important questions on how to contain drug prices in State Medicaid programs. If the principles of the Medicare Part D program--including the necessary patient protections--were applied to State Medicaid programs, do you think it lower drugs costs while ensuring access to patients? Answer. There are important differences in the population covered under Medicaid and the coverage options available that need to be considered. Medicaid beneficiaries remain some of the sickest and most complex populations of patients, with sometimes inconsistent relationships with health-care providers and other complicating factors that make accessing medical care already difficult. Many Medicaid patients have complex diseases for which there are not always therapeutically equivalent drugs available, so access to the specific drug providers prescribe is crucial. Part D is a highly competitive, successful program that has come in at nearly half the cost that was originally projected. It also has extremely high rates of beneficiary satisfaction--generally around 90 percent. While Part D offers multiple plan options and levels of benefits such that patients can shop for plans that cover their medicines at varying levels of cost-sharing, patients in Medicaid do not have access to alternative coverage options. So, if a medicine they need is not available, they do not have the ability to switch plans or otherwise obtain access to the medicine. As a result, the use of restrictive formularies is likely to result in adverse effects on beneficiary outcomes and increased costs when applied in Medicaid. While the patient protections that exist in Part D may provide beneficiaries with an option to appeal formulary decisions, it would be complicated to navigate for Medicaid patients and their providers, who may have limited resources to take on the additional responsibility and may take time that patients with complex conditions may not have. Medicaid is already receiving the best price based on the statutory rebate and States have flexibility to exert utilization management controls to negotiate supplemental rebates. Given this, we believe that applying the principles of Medicare Part D in Medicaid is not likely to result in lower drug costs without significantly impacting access. medicaid ``best price'' Question. In the Trump administration's Blueprint, they suggested that because drug manufactures have to give Medicaid the ``best price'' on drugs, there is no incentive to offer deeper discounts to other payers--both government and commercial--than what is already offered under the Medicaid Drug Rebate Program. Does the Medicaid ``best price'' requirement encourage manufacturers to increase initial prices? What, if any, changes would you suggest we make to the program? Answer. We can speak only to Merck's practices, and Merck does not consider the Medicaid Best Price requirement when setting initial prices. Merck approaches pricing from the perspective of value. This approach looks at the value that a medicine provides through multiple lenses with the goal of reflecting its benefit to patients and to society, while at the same time paying an appropriate return on invested capital to our investors, to ensure that we are able to sustain R&D. While each individual situation varies based on factual circumstances and market dynamics, generally, we consider: Value provided to patients--to what extent does a new medicine or vaccine establish a new standard of care that has the potential to significantly extend and improve patient lives? Value provided to health-care systems--to what extent does a new medicine or vaccine reduce the costs associated with hospitalization and other costly complications of disease if not appropriately (or optimally) treated? Unmet need--does a new medicine or vaccine address a critically unmet medical need, where few or no treatments exist? Access--what is the ability of various customers around the world--including national, regional or local institutional payers, physicians, employers and patients--to pay for our products? R&D sustainability--given the long-term risk and cost of capital, can we appropriately compensate our investors to ensure continued investment in the kind of risky and capital- intensive research and development that will bring forward medically-important breakthroughs? Competition--what are the costs of other treatments currently on the market relative to the value provided by Merck's products? We recognize the value that the Medicaid program provides for patients who need it, and we do not believe the ``best price'' requirement encourages manufacturers to increase initial prices. Merck believes that the exclusion of value-based arrangements (VBAs) from the calculations of Best Price, Average Manufacturer Price, and Average Sales Price would facilitate VBA implementation, which would further align prices with the value that pharmaceutical products bring to the market. outcomes-based contracts Question. In almost all of your testimonies, you highlight your support of outcomes-based contracts and how we need to be shifting our system toward that approach. How will these contracts lower drug costs for patients in both the near term and long-term? How will they lower overall health-care costs for our Federal programs? What have the preliminary results looked like so far? Answer. For more than 10 years, Merck has worked with payers and health-care providers to advance alternative pricing and contracting arrangements and Merck has publicly shared information about value- based agreements (VBAs) it entered into with the payers Aetna and Cigna. We are continuously reviewing ways in which the company may enter into VBAs for our products, which we define as a contractual framework aimed at achieving a mutually agreed upon value objective that that drives greater value from health-care spending. Merck is interested, where business and customer objectives align, to implement VBAs across the health-care market, including Medicare Part D, Managed Medicaid, and Fee-For-Service Medicaid. By aligning payments for medicines more directly with their value in improving meaningful health outcomes and/or reducing the need for other health-care services (such as hospitalizations), VBAs make pharmaceutical manufacturers accountable for the results their products achieve in a concrete way and can help improve patients' health and maximize the benefits of health-care spending. A recent Avalere survey of payers found that 44 percent of payers engaged in outcomes-based contracts experienced improvements in patient outcomes.\8\ --------------------------------------------------------------------------- \8\ Avalere Health. ``Outcomes-Based Contracts: Payer Perspectives.'' Avalere Policy 360. July 19, 2018. VBAs also can increase patient access to new therapies which could ultimately improve patient outcomes. A payer that might otherwise decline to cover a new medicine (or that would only cover the medicine with significant utilization management restrictions or high cost sharing) due to uncertainties about the expected percentage of its patient population who would benefit might increase access to the medicine if the manufacturer shared the risks of the medicine's performance. These agreements may make medicines more accessible to patients who will benefit from them and increase competition in relevant therapeutic classes.\9\ Researchers have found that value- based arrangements can improve patient access to medicines.\10\ --------------------------------------------------------------------------- \9\ Staley, L. ``A Drug's Worth: Why Federal Law Makes it Hard to Pay for Pharmaceutical Performance.'' Boston University Law Review. 2018;98(1):303-334. (``Tying reimbursement to health outcomes presents new opportunities for competition with rival manufacturers. . . . [A] manufacturer that can demonstrate sustained health benefits in post- market studies may distinguish itself from competitors.''). \10\ See, for example, description of Entresto and Repatha contracts in: Seely, E., and Kesselheim, A. ``Outcomes-Based Pharmaceutical Contracts: An Answer to High U.S. Drug Spending?'' Commonwealth Fund. Issue Brief. September 2017. While Merck has had some experience with VBAs, these efforts have not been as robust as they could be due to the challenges involved in developing and implementing them. In addition to infrastructure and data limitations, challenges include regulatory limitations such as government pricing frameworks (e.g., Medicaid Best Price (BP) rules, --------------------------------------------------------------------------- Medicare's Average Sales Price (ASP)) and Federal fraud and abuse laws. Accordingly, we support opportunities that would enable greater experimentation in the design, structure, and implementation of VBAs. Further innovation in this space is needed to support overall sponsor and plan learning, and to determine the range of potential benefits to diverse health systems and beneficiaries. To fully achieve these goals, however, the impacts of the current regulatory framework, including government pricing requirements, the Federal Anti-Kickback Statute (AKS), and overall environmental barriers, must be analyzed and addressed as appropriate. Policy solutions such as the Patient Affordability Value and Efficiency Act (PAVE), introduced by Senators Warner and Cassidy, could provide necessary regulatory flexibility for properly structured VBAs. transparency/point of sale Question. In almost all of your testimonies, you express your support for the Trump administration's proposal to allow manufacturers to provide PBMs up-front discounts that are passed onto patients at the point-of-sale. Do you feel like this proposal will make the transactions within the drug supply chain more transparent? If so, would this transparency bring down drug costs--overall and for specialty drugs? Answer. We believe we must change the system to ensure that patients receive the benefit of the significant rebates and discounts that manufacturers like Merck pay to PBMs and plans. The proposed rule is a positive step in that direction. Based on our initial assessment of the proposal, we believe that it will remove misaligned incentives within the system, drive more transparency in the system, and most importantly, lower beneficiaries' out-of-pocket costs. the relationship between wholesalers and manufacturers Question. When talking about the pharmaceutical supply chain, a lot of focus has been placed on the Pharmacy Benefit Manager. But there's another side of the equation that I'd like to ask about. How do wholesalers negotiate pricing with manufacturers? What impact does this have on drug costs? What incentives or disincentives do they have to contain price increases? Answer. There are many entities supporting the distribution and dispensing of pharmaceutical products. Wholesalers purchase pharmaceutical products directly from manufacturers and subsequently sell those products to sites of care for dispensing. Downstream customers of the wholesalers include retail and specialty pharmacies, hospitals, clinics, and others. Those entities that purchase from the wholesalers ultimately dispense or administer the drug to patients. Many manufacturers typically offer a ``prompt pay'' discount to wholesalers in exchange for timely payment of invoices (2 percent for payment within 30 or 35 days is fairly standard in the industry). Manufacturers also contract with wholesalers for services that support the appropriate storage and distribution of product to appropriate customers within the supply chain. These ``Distribution Service Agreements'' provide wholesalers with an opportunity to earn fees based on performance against pre-defined metrics that are part of a set of standard services. These services include managing inventory levels, achieving defined service levels, consolidating receipt of inventory to a central location, and administering contract pricing and chargebacks. Although these distribution service fees manufacturers pay to wholesalers are commonly administered as a percent of the list price, they are negotiated at arm's length and are based on fair market value for the services rendered. The terms of wholesaler agreements with their downstream customers vary; however, in general, the prices they offer to their customers are set relative to a product's list prices. In general, fees paid to wholesalers by manufacturers are modest and wholesaler economics (including both buy and sell side) are not likely to influence the setting of a product's list price. ______ Questions Submitted by Hon. Ron Wyden proposed rebate rule Question. As has been done in many other settings, drug manufacturers said during the hearing that one reason list prices for drugs are high is that pharmaceutical benefit managers (PBMs) demand larger and larger rebates in order for the drug to receive favorable placement on a formulary. You and your colleagues who testified during the hearing stated if the administration's proposal on changes to the anti-kickback safe harbor for pharmaceutical rebates took effect, your company would likely lower list price. Like many Oregonians, I am skeptical drug manufacturers would voluntarily lower their prices. Therefore, would you support legislation that would (1) make similar changes the administration has put forward related to Part D and Medicaid managed care, (2) change the rebate system in a similar way to the proposal for the commercial market, and (3) require drug makers to lower the list price of their drugs equal to the amount of rebates provided today? Answer. We believe we must change the system to ensure that patients receive the benefit of the significant rebates and discounts that manufacturers like Merck pay to PBMs and plans. The proposed rule is a positive step in that direction. Based on our initial assessment of the proposed rule, we believe that it will remove misaligned incentives within the system, drive more transparency in the system, and most importantly, lower beneficiaries' out-of-pocket costs. Merck supports the earliest possible implementation of the proposed rule that can be achieved without creating disruption for the beneficiaries who rely on Medicare for their drug coverage. We are committed to working with the PBMs and health plans and other intermediaries to make this happen. We do not support legislation to require manufacturers to lower their list price equal to the amount of rebates today. First, different purchasers receive different levels of discounts, based on individualized negotiations and the formulary positioning of Merck's products. So, there is not a uniform ``rebate amount'' that could reduce the list price. Moreover, we expect that the robust negotiations that occur today will continue in the highly competitive Part D market, and we expect to realize the same level of net price that we do today. In fact, we expect that there could be additional pricing pressure under the new system, which could lead to lower net prices. Over time, we expect that our list prices will go down if the misaligned incentives across the system are addressed. We are currently working with other stakeholders in the system to solve the operational challenges that will enable these changes. But, it is also important to note that if the rule is implemented, Medicare beneficiaries' out-of-pocket costs will be reduced, independent of any lowering of list prices, since their cost-sharing will be based on the net price. Nonetheless, we believe the rebate rule will align incentives in a way that will restrain list prices. As we stated when we reduced the list price of several of our products in July 2018, we have continued to look for opportunities to reduce our list prices. We think the proposed rule would help create those opportunities, but it can't happen overnight. All the players in the ecosystem will need to adjust to the new model. We are actively working to support the move to a contracting model in Part D that would change the incentives to support lower list prices. Lowering list prices is not an easy thing to do in our health-care system: One of the key challenges to lowering list prices is the contractual arrangements that companies have with PBMs and health plans, which are intended to ensure access to our products. These contracts are often multi-year and are most often written to provide a discount off of the list price, which is paid as a rebate later. To reduce the list price without significant financial consequences, all of these contracts would need to be modified to maintain the same net price. Unless the entire system changes, one manufacturer runs the risk of being disadvantaged and losing formulary status or being required to pay the same percentage discount on a lower list, which could be unsustainable. In addition, drugs flow through a complex supply chain, from the manufacturer, to the wholesaler, to a pharmacy or hospital who dispenses the drug to patients. For any product but even more so for a high volume primary care product that is flowing through to all pharmacies and hospitals, there is not a mechanism in place to readjust the value of the inventory being held by all those parties. If the proposed rule is implemented as written, it would only apply to our contracts with PBMs and health plans for Medicare Part D and Managed Medicaid. If PBMs and health plans maintain the rebate model in the commercial market, we would still have commercial contracts based on rebates, which would be subject to the existing constraints to lowering list price. We also would still need a mechanism to revalue drug in the distribution channel in a financially viable manner. medicaid drug rebate program Question. The Medicaid Drug Rebate Program (MDRP) requires manufacturers to provide a basic rebate and an additional inflationary rebate for both brand and generic drugs. The inflationary rebate is an increasingly substantial part of total rebates due in large part to large increases in drug prices that exceed inflation. Under current law, this inflationary rebate is capped at 100 percent of Average Manufacturer Price (AMP). This is the case even when manufacturers continue to raise their prices well above inflation. Please provide a list of all of your pharmaceutical products that have reached the Medicaid AMP rebate cap in any of the 20 quarters from January 1, 2014 through December 31, 2018. For each drug listed in response to question 1, please also provide a list of which quarters and years each drug hit the cap. Answer. Merck conforms to all statutory, regulatory, and sub- regulatory guidance regarding its participation in the Medicaid Drug Rebate Program, including the payment of Medicaid rebates. The information requested by this question, however, is confidential, proprietary, and commercially and competitively sensitive. Merck would be happy to explore other means to share this information with the committee in a confidential fashion. medicaid drug rebate program compliance Question. I am concerned about recent reports and legal settlements surrounding drug manufacturers' failure to comply fully with the requirements of the MDRP. For example, an analysis by the U.S. Department of Health and Human Services Office of Inspector General found that between 2012 and 2016 taxpayers may have overpaid by as much as $1.3 billion for 10 potentially misclassified drugs. That is why I introduced the Right Rebate Act with Chairman Grassley to prevent drug manufacturers from manipulating Medicaid to increase their profits. However, I continued to be concerned about oversight and manufacturer compliance with the requirements of the Medicaid Drug Rebate Program. Accordingly, please describe the following: Your company's current compliance plan and procedures used to ensure compliance with the requirements of the Medicaid Drug Rebate Program including internal audits or other checks you use to identify compliance vulnerabilities. Answer. Merck's government price reporting team--in consultation with in-house attorneys, outside counsel, and third-party vendors as appropriate--maintains comprehensive and detailed government price reporting policies, procedures, and reasonable assumptions for compliance with all price reporting programs, including the Medicaid Drug Rebate Program (MDRP). Merck's policies are evaluated and updated, as needed, on an annual basis by the government price report team, in- house attorneys, and outside counsel to ensure that they are consistent with current regulations and applicable guidance from the Centers for Medicare and Medicaid Services (CMS). Additionally, Merck's reasonable assumptions are evaluated and updated, as needed, on a monthly basis for Average Manufacturer Price and on a quarterly basis for Best Price by the government price reporting team, in-house attorneys, and outside counsel. Merck has a long history of transparency and communication with CMS regarding its MDRP compliance and reasonable assumptions, and company compliance personnel regularly oversee Merck's price reporting operations. Merck evaluates any new guidance issued by CMS to ensure that its price reporting calculations and processes are in compliance with the law. Question. Any past or ongoing issues of non-compliance. Answer. Merck maintains comprehensive and detailed reasonable assumptions for its MDRP participation. In situations in which Merck is uncertain about a calculation approach that is not clearly addressed in CMS rules or guidance, the company documents its approach in assumptions and/or discloses its intended approach to CMS. Additionally, given the complexity of the calculations, Merck may identify calculation mistakes or other issues that require correction. This may happen, for example, to the extent that Merck believes that any new CMS rules or guidance call into question a reasonable assumption that the company has previously maintained. In such cases, if Merck has any concern about its program compliance, it promptly communicates with CMS to seek the agency's guidance and potentially restate its prior MDRP reports. Question. Any corrective actions taken to address identified problems or issues of non-compliance with the MDRP and how such steps were communicated to the Centers for Medicare and Medicaid Services. Answer. As noted above, to the extent that Merck believes that any of its existing calculation or compliance processes for MDRP participation are not in keeping with current CMS rules or guidance, the Company would promptly engage with the agency to identify any necessary remedial steps and the appropriate way forward, including filing pricing restatements. Question. Any steps taken to improve compliance and ensure that all Medicaid drug rebates owed to the Federal Government and the States are paid in full. Answer. As noted above, Merck takes its government price reporting obligations very seriously, and the Company maintains robust, ongoing legal and compliance oversight of its price reporting team and its operations. As discussed above, we routinely review our policies, procedures, and reasonable assumptions to ensure compliance with current law. Merck also has an annual training requirement for government price reporting compliance. If Merck were to identify any potential noncompliance issue associated with the underpayment of rebates to the State Medicaid Programs, Merck immediately would identify this issue to CMS and would work with the agency to ensure the implementation of any appropriate remedy (including restating pricing metrics and reconciling rebate amounts with the States). bonus payments tied to specific drugs Question. I am concerned by the potential for employee financial incentives to encourage high launch prices and price increases for prescription drugs. Is your salary, bonus, or other compensation tied to sales or revenue targets of a single product your company sells? Has it ever been? If yes, please state the product or products to which your salary, bonus, or other compensation was tied. Answer. My salary, bonus, or other compensation is not tied to sales or revenue targets of a single product that Merck sells. In 2011, a very small percentage of my annual bonus was tied to the net sales of 3 new products (DULERA, SIMPONI, and VICTRELIS). Question. Is your salary, bonus, or other compensation tied to either revenue or net income of the company as a whole? Has it ever been? If yes, please explain what assumptions about price increases are used when the compensation committee sets revenue or net income goals. Does the compensation committee provide any guidance to executives in regards to the amount of revenue that the company will generate from price increases versus volume growth? Answer. Yes, a portion of my annual bonus is tied to revenue and pretax income (i.e., a variation of net income) of the company as a whole, with each contributing 40 percent (for a total of 80 percent) to the aggregate incentive target, and research and development productivity constituting the other 20 percent of the target. The final bonus that I receive is then calculated based on the company's actual performance for those three metrics. The Compensation and Benefits Committee of the Board sets annual targets for revenue and pretax income based upon the company's annual plan, as approved by the full Board of Directors. The company's annual plan includes U.S. pricing assumptions informed by several variables, including volume, price, and discount rates, which for 2019 are fully consistent with our July 19, 2018 commitment to not increase net price across our product portfolio in the U.S. by more than inflation annually. Neither the board of directors as a whole, nor the Compensation and Benefits Committee specifically, provides guidance to executives with regard to the amount of revenue that the company will generate from price increases versus volume growth. net prices Question. In your testimony, you stated, ``last year we pledged that we will not increase our average net prices for our portfolio by more than the rate of inflation annually,'' and that ``From 2010 to 2017, Merck's average net price increase across our portfolio each year has been in the low to mid-single digits. In fact, our average net price declined in 2017 by almost 2 percent. In 2017, the average discount for our medicines and vaccines was more than 45 percent lower than the list price.'' Please describe how the company's year-over-year aggregate net price is calculated. Please also specifically address the following questions: Answer. Net Price Change represents the year-over-year change in average net price, which is Wholesale Acquisition Cost (WAC) less rebates, discounts, and returns. The annual percent change versus prior year was calculated at a product level and weighted across the company's U.S. Product Portfolio. U.S. Product Portfolio includes human health pharmaceutical and vaccine products marketed by the company, excluding partnered products. The product sales utilized in the analysis represent 97 percent of the total U.S. Product Portfolio in 2010, increasing each year to approach 99.8 percent of coverage in 2017. Question. How many products are included in the calculation of the average net price change? What was the median net price change? Answer. In 2017, 78 products were included. The median net price change was 0 percent. Question. Is net price weighted? If so, how? For example, in determining the aggregate net price does the company assign different weights to different products based on volume or other factors? Are ``on patent'' and ``off patent'' drugs weighted identically? Are other statistical weights used or are all products treated equally? Answer. The Net Price Change percent for each product is weighted by its Net Sales relative to the Total Net Sales of the Product Portfolio for the current year. On and off patent drugs are calculated in the same fashion, and no other ``statistical weighting'' is applied. Question. Does the figure that you provided during your testimony account for U.S. prices, international prices, or both? Generally speaking, when your company reports net price changes, does it differentiate between U.S. and international prices? Answer. Only U.S. prices are used in the report. Question. Please list the five drugs your company sold in the U.S. that had the greatest year-over-year net price increase in 2018, noting the increase for each drug by dollar figure and percentage. Please list the five drugs your company sold in the U.S. that had the lowest year- over-year net price increase (and/or the greatest decrease) in 2018, noting the increase (or decrease) for each drug by dollar figure and percentage. Answer. The product-specific information requested is competitively sensitive and Merck therefore cannot produce it in a public setting in which it could be accessed by competitors. However, Merck does report similar information in an aggregated format in its annual price transparency report, which we proactively make available on our corporate responsibility website: https://s3.amazonaws.com/msd18-assets/wp-content/uploads/2019/02/ 281553 45/2018-US-PRICING-TRANSPARENCY-REPORT_02.2019.pdf The report sets forth the average annual list price changes across the Merck portfolio as well as other price related information concerning Merck medicines and vaccines. The report shows that in 2018 the average annual list price across the Merck portfolio increased by 5.5 percent--the lowest increase since 2010--as compared with a 6.6 percent increase in 2017. In 2018, the Company's gross U.S. sales were reduced by 44.3% as a result of rebates, discounts and returns. The below chart reflects additional information about the price changes for Merck products. U.S. Product Portfolio Percent Change vs. Prior Year ---------------------------------------------------------------------------------------------------------------- 2010 2011 2012 2013 2014 2015 2016 2017 2018 ---------------------------------------------------------------------------------------------------------------- List Price Change (WAC) 7.4 9.5 9.2 9.6 10.5 9.8 9.6 6.6 5.5 ---------------------------------------------------------------------------------------------------------------- Net Price 3.4 5.1 6.2 5.5 3.7 5.5 5.5 (1.9) 2.99 ---------------------------------------------------------------------------------------------------------------- U.S. Product Portfolio ---------------------------------------------------------------------------------------------------------------- Average Discount (%) 27.3 28.9 29.9 32.1 37.0 38.2 40.9 45.1 44.3 ---------------------------------------------------------------------------------------------------------------- Question. For 2018, what was the average net price change in the U.S. market for (1) drugs with no competition, (2) drugs with only branded competition, and (3) drugs with generic competition? Answer. The product-specific information requested is competitively sensitive and Merck therefore cannot produce it in a public setting in which it could be accessed by competitors. However, Merck does report similar information in an aggregated format in its annual price transparency report, which we proactively make available on our corporate responsibility website: https://s3.amazonaws.com/msd18-assets/wp-content/uploads/2019/02/ 281553 45/2018-US-PRICING-TRANSPARENCY-REPORT_02.2019.pdf The report sets forth the average annual list price changes across the Merck portfolio as well as other price related information concerning Merck medicines and vaccines. The report shows that in 2018 the average annual list price across the Merck portfolio increased by 5.5 percent--the lowest increase since 2010--as compared with a 6.6- percent increase in 2017. In 2018, the company's gross U.S. sales were reduced by 44.3% as a result of rebates, discounts and returns. The below chart reflects additional information about the price changes for Merck products. U.S. Product Portfolio Percent Change vs. Prior Year ---------------------------------------------------------------------------------------------------------------- 2010 2011 2012 2013 2014 2015 2016 2017 2018 ---------------------------------------------------------------------------------------------------------------- List Price Change (WAC) 7.4 9.5 9.2 9.6 10.5 9.8 9.6 6.6 5.5 ---------------------------------------------------------------------------------------------------------------- Net Price 3.4 5.1 6.2 5.5 3.7 5.5 5.5 (1.9) 2.99 ---------------------------------------------------------------------------------------------------------------- U.S. Product Portfolio ---------------------------------------------------------------------------------------------------------------- Average Discount (%) 27.3 28.9 29.9 32.1 37.0 38.2 40.9 45.1 44.3 ---------------------------------------------------------------------------------------------------------------- Question. In Merck's most recent pricing transparency report, the company notes that the ``the average annual net price across our portfolio declined by 1.9 percent, reflecting specific in-year dynamics, including the impact of loss of patent protection for three major medicines.'' Please identify these medicines, and the net price change for each of them on a dollar and percentage basis for 2017. What was Merck's average net price increase/decrease in 2017 for drugs excluding these three medications? Answer. This information is confidential, proprietary, and commercially sensitive. Merck's average net price increase/decrease in 2017 excluding the three drugs referred to is -0.6 percent. Question. In Merck's pricing transparency report, the company states that its net price is ``represents the year-over-year change in average net price, which is WAC less rebates, discounts and returns,'' while its average discount is ``weighted . . . [and] calculated by dividing annual rebates, discounts and returns by annual gross sales.'' Please clarify whether the company's average net price is weighted for purposes of complying with its publically stated pledge. Answer. Yes, the average net price is weighted. ______ Questions Submitted by Hon. Robert Menendez Question. When new products enter the market, do drug companies set high initial rebates and then provide deep rebates in order to gain access to insurance plan's formularies? Answer. Merck approaches pricing from the perspective of value. This approach looks at the value that a medicine provides through multiple lenses with the goal of reflecting its benefit to patients and to society, while at the same time paying an appropriate return on invested capital to our investors, to ensure that we are able to sustain R&D. While each individual situation varies based on factual circumstances and market dynamics, generally, we consider: Value provided to patients--to what extent does a new medicine or vaccine establish a new standard of care that has the potential to significantly extend and improve patient lives? Value provided to health-care systems--to what extent does a new medicine or vaccine reduce the costs associated with hospitalization and other costly complications of disease if not appropriately (or optimally) treated? Unmet need--does a new medicine or vaccine address a critically unmet medical need, where few or no treatments exist? Access--what is the ability of various customers around the world--including national, regional or local institutional payers, physicians, employers and patients--to pay for our products? R&D sustainability--given the long-term risk and cost of capital, can we appropriately compensate our investors to ensure continued investment in the kind of risky and capital- intensive research and development that will bring forward medically important breakthroughs? Competition--what are the costs of other treatments currently on the market relative to the value provided by Merck's products? When the company launched ZEPATIER into the Hepatitis C market, Merck chose a low list price strategy, while competitors had a higher price with significant rebates. Unfortunately, we were unable to gain reasonable formulary status or resulting sales in certain market segments with this strategy. Positive actions in the U.S., such as the administration's proposal regarding the rebate safe harbor could provide incentives for lower initial list prices in the future. Question. If CMS finalizes the rebate rule, do you anticipate future products entering the market with significantly lower initial list prices? Answer. Over time, we expect that list prices will go down if you remove the misaligned incentives in the system. It is also important to note that if the rule is implemented, Medicare beneficiaries' out-of- pocket costs will be reduced--independent of any lowering of list prices--since their cost-sharing will be based on the net price. But we believe the rebate rule will align incentives in a way that will restrain list prices. If this rule is implemented as written, it would only apply to our contracts with PBMs and health plans for Medicare Part D and Managed Medicaid. If PBMs and health plans maintain the rebate model in the commercial market, we would still have commercial contracts based on rebates, which would be subject to the existing constraints to lowering list price. We also would still need a mechanism to revalue drug in the distribution channel in a financially viable manner. ______ Questions Submitted by Hon. Thomas R. Carper Question. What are your recommendations for lowering prices for the 40 percent of drugs that do not offer rebates in Medicare Part D? Answer. Assuming the 40 percent reference is correct, we believe that the administration's rebate safe harbor proposal will lead to lower prices even for products which currently may offer no or minimal rebates in Medicare Part D. We believe the increasing transparency of prices will spur heightened competition even in classes and for products where rebating has been limited in the current system. Similarly, the fact that price concessions will be made directly available to patients will also create a price-reducing dynamic since price concessions will make products more affordable to patients, resulting potentially in greater adherence and appropriate use of prescribed medicines, clearly benefiting patients and encouraging manufacturers to offer price concessions. Additionally, assuming policy changes are made to further incentivize value-based contracts, we believe that value-based contracts can also help to restrain initial list prices by tying those prices to the value that the products bring to patients and the health-care system. Question. In the health insurance plans that you offer your employees, do you ask your insurers to pass through the full manufacturer rebates to the beneficiaries? Answer. Merck offers a generous health-care benefit for our 24,000 U.S. employees. There is no deductible for medications covered under our pharmacy benefit, and employees never have to pay more than $50 for a retail prescription for a covered medication, and in most cases pay less. We contract with a PBM for management of the prescription drug benefits for our employees, and the benefit does not offer point-of- sale rebates to our employees. Merck uses savings generated by rebates to lower overall costs for employees while ensuring low out-of-pocket costs. Question. The systems for pricing and distributing drugs are opaque and difficult to understand. What are your recommendations for increasing transparency in how your companies set the list prices for drugs, and for improving transparency in the supply chain for prescription drugs? Would you support Federal standards for transparency in setting the list prices for drugs? Answer. We are open and transparent about the factors we consider in setting prices. Merck approaches pricing from the perspective of value. This approach looks at the value that a medicine provides through multiple lenses with the goal of reflecting its benefit to patients and to society, while at the same time paying an appropriate return on invested capital to our investors, to ensure that we are able to sustain R&D. While each individual situation varies based on factual circumstances and market dynamics, generally, we consider: Value provided to patients--to what extent does a new medicine or vaccine establish a new standard of care that has the potential to significantly extend and improve patient lives? Value provided to health-care systems--to what extent does a new medicine or vaccine reduce the costs associated with hospitalization and other costly complications of disease if not appropriately (or optimally) treated? Unmet need--does a new medicine or vaccine address a critically unmet medical need, where few or no treatments exist? Access--what is the ability of various customers around the world--including national, regional or local institutional payers, physicians, employers and patients--to pay for our products? R&D sustainability--given the long-term risk and cost of capital, can we appropriately compensate our investors to ensure continued investment in the kind of risky and capital- intensive research and development that will bring forward medically important breakthroughs? Competition--what are the costs of other treatments currently on the market relative to the value provided by Merck's products? Question. In nearly every sector of the health-care industry, Medicare, Medicaid, employers, and insurers are moving away from fee- for-service payments to reimbursements based on value and performance. Prescription drugs and medical devices were the glaring exceptions to this trend until recently. How many of your drugs are included in value-based contracts and how many patients are benefiting from them? How do these value-based contracts work to lower drug prices for both patients and taxpayers? Answer. Merck has been party to value-based discounting arrangements for four of its products. It is difficult to assess exactly how many patients have benefitted from them, however, since that information is not in Merck's possession under the arrangements. Merck agrees that value-based discounting strategies can benefit patients and the Federal health care programs by ensuring that payment aligns with the value or outcomes that a manufacturer's products bring to the system. If, for example, a value-based agreement demonstrates that a manufacturer's product helps patients to achieve meaningful clinical outcomes (or even to avoid more serious illness complications or comorbidities), the product would have demonstrated a savings to patients and taxpayers (for example, by avoiding hospitalization or further treatment for a particular condition). There are, however, significant impediments under current law regarding adopting this type of contract--including under the Anti-Kickback Statute and manufacturer government price reporting obligations--and Merck supports legislative or regulatory reforms to increase the proliferation of value- or outcomes-based discounting. Question. Last year, Senator Portman and I did an investigation on the pricing of an opioid overdose reversal drug called EVZIO, manufactured by Kaleo. Kaleo increased the price of EVZIO from $575 in 2014 to $4,100 in 2017. We found that the best price Medicare was able to get for EVZIO, about $4,000, was much higher than the price other Federal programs and private insurers were able to get. It seemed that Kaleo was able to get this higher price of $4,000 from Medicare by helping doctors fill out paperwork showing that the drug was medically necessary, even though there are cheaper alternatives on the market. As a result of the investigation, Kaleo announced it will bring a generic version of the drug to market at only $168 per pack. Are any of your companies providing medical necessity paperwork to doctors in order to get your drugs covered by Medicare? Answer. In the United States, Merck provides limited reimbursement support for patients in connection with the purchase of certain of Merck's products following a physician's prescribing decision (in accordance with Department of Health and Human Services Office of Inspector General guidance). In certain cases, this support includes identifying--for patients and physicians--the appropriate forms and insurance processes attendant to securing insurance coverage for our products. But it is Merck's policy never to interfere with the physician-patient relationship or the decision about whether to seek insurance coverage. Question. In 2017, the Rand Corporation estimated that biosimilar drugs, which are competitors to complex, biologic drugs, could save the United States more than $50 billion over the next decade. Some of you have also argued that increasing the use of biosimilar drugs would help lower drugs costs for consumers and taxpayers. What is delaying the uptake of biosimilar drugs in the United States? What policies do you recommend to increase the development of biosimilar drugs? Answer. Merck agrees that we can significantly reduce spending on pharmaceuticals, especially for patients, by ensuring that we have a viable market for biosimilars in the United States. We believe, like with traditional small molecule medicines, generic competition after a reasonable period of exclusivity will create headroom for patients to afford the newest, most innovative medicines. In addition to the RAND data that you referenced, other research shows that generics and biosimilars are expected to drive savings of $105 billion through 2022 in the U.S.\11\ --------------------------------------------------------------------------- \11\ IQVIA. ``Medicine Use and Spending in the U.S.: A Review of 2017 and Outlook to 2022.'' (Apr. 19, 2018), https://www.iqvia.com/ institute/reports/medicine-use-and-spending-in-the-us-review-of-2017- outlook-to-2022. We suggest the following policy changes to help encourage and --------------------------------------------------------------------------- support prescriber biosimilar utilization: Consider options to reduce or eliminate patient cost sharing in Medicare Part B for biosimilars. While some Part B beneficiaries are already able to reduce their 20 percent cost sharing via supplemental coverage, we believe eliminating cost sharing will encourage many physicians to use biosimilars for their patients. A similar approach in Part D and in Medicaid for small-molecule generics has driven generic utilization up to 90 percent.\12\ --------------------------------------------------------------------------- \12\ Department of Health and Human Services. Office of Inspector General. ``Generic Drug Utilization in the Medicare Part D Program.'' (Nov. 2007), https://oig.hhs.gov/oei/reports/oei-05-07-00130.pdf. Create pathways for MA and Part D plans to receive bonus payments and/or enhanced star ratings for achieving metrics related to access to biosimilars. This will incentivize plans to implement policies that drive additional utilization of --------------------------------------------------------------------------- biosimilars. Consider alternative reimbursement methodologies that adjust the current Part B reimbursement formula. The current structure in Part B to reimburse at ASP + 6 percent of the reference product ASP ensures there is no reimbursement downside to physicians for using biosimilars. But so far, the evidence does not suggest the current reimbursement rate sufficiently incentivizes providers to use biosimilar products. The administration should consider alternatives to further incentivize physician adoption of biosimilars. ______ Questions Submitted by Hon. Benjamin L. Cardin Question. The United States is one of the only countries in the world to allow prescription drug manufacturers to advertise directly to consumers through magazines, billboards, radio, and television commercials. While I will not argue that it is beneficial to educate consumers about an unfamiliar disease and encourage them to seek medical help, most commercials from all of your companies recommend asking about a specific brand name drug, not a medical condition. Furthermore, even if your advertisements follow all FDA rules and list medication side effects, they also almost always list these while a smiling, apparently healthy person is walking on a beach. Researchers say that this type of imagery, combined with viewing hours of drug commercials each month, leads consumers to underestimate the risks associated with medications. For the past decade, studies have shown that aggressive direct-to-consumer advertising is associated with rising drug prices and an increase in inappropriate drug prescriptions. Since researchers have concluded that consumers are misunderstanding the benefits and risks described in your ads, what further policies could help you and your colleagues ensure that you are educating patients in a clear manner? Answer. Merck believes that direct-to-consumer (DTC) advertising can be an important and helpful way to inform patients about diseases that may be relevant to them and therapeutic options they may want to discuss with their physician. Data demonstrate that DTC can have a positive impact on patient health in terms of diagnosis, treatment, and adherence to prescribed therapies. We recognize that DTC is one channel amongst many to help educate patients. Print materials, telephone, websites, and other channels are also used to provide more in-depth information to patients. The ultimate decision to prescribe a product for any specific patient remains with the physician following discussion with their patient. Merck adheres to FDA regulations and guidelines governing DTC promotion and has a long-standing policy to voluntarily submit new DTC broadcast advertising campaigns to FDA for pre-review. Merck also follows the PhRMA Guiding Principles for DTC Advertisements About Prescription Medicines. We are currently considering what additional information we can make available to consumers to ensure that they can make informed health care decisions. pharmaceutical companies continue to raise prices Question. As you are well aware, high prescription drug prices are the number one concern for Americans and their families. According to the Organization for Economic Cooperation and Development, the average American spends around $1,208 annually on prescription drugs. There have been several instances where brand name or even generic drugs that have been on the market for years continue to increase in price. One of the most well-known examples is Mylan's increase of the price of EpiPen from less than $100 in 2007 to more than $600 in 2016. Another example is the ever-increasing price of insulin. Sanofi increased the price of a vial of Lantus from $88.20 in 2007 to $307.20 in 2017. And those are just a small sample of price increases. Why don't we see price decreases for drugs that have been on the market for years without new formulations or added benefit? Answer. List prices do not generally decline largely owing to many of the misaligned incentives that the administration's rebate safe harbor proposal is designed to address. Specifically, rebate contracts for commercial and Medicare Part D payers/PBMs are designed as set percentages from the list price. Lowering list prices while maintaining these same percentage discounts/rebates usually precludes the commercial viability of reducing list prices. We do in fact see price decreases for products that have been on the market for years--extremely large ones. They occur at the time of patent expiry, and often reduce prices by over 90 percent. This is unlike any other part of the health care system we are aware of, where prices drop massively after a specified period. If these massive one- time price reductions occurred more gradually, it would be far more obvious that prices were decreasing. Even putting this aside, net prices on many products drop dramatically over time as competition from new products increases. For instance, the average net price of our anti-diabetes medicine Januvia is less today than it was when it was launched in 2007. pay for delay Question. Pay for delay is a tactic that more and more branded drug manufacturers have been using to stifle competition from lower-cost generic manufacturers. This allows you to sidestep competition by offering patent settlements that pay generic companies not to bring lower-cost alternatives to market. These ``pay-for-delay'' patent settlements benefit both brand-name pharmaceutical companies by helping them avoid costly patent litigation and general manufacturers by rewarding them a hefty sum to delay entering the market with a cheaper drug alternative. However, these deals do not benefit consumers. According to an FTC study, these anticompetitive deals cost consumers and taxpayers $3.5 billion in higher drug costs every year. Does your company partake in pay-for-delay settlements? Answer. Merck has not entered into patent settlement agreements with generic companies to delay their entry past when it would otherwise be lawful for them to enter the market. Merck has been party to a number of patent settlement agreements that provide for generic market entry prior to patent expiry, including some that have provided some level of exclusivity for a limited time. These agreements allowed generic products to enter the market earlier than would have otherwise been the case. The FTC has not challenged as anti-competitive any of these types of agreements involving Merck. Question. Why would a pharmaceutical company enter into a pay-for- delay agreement? Answer. Parties enter into settlements of patent litigation for all the same reasons parties settle other civil litigation. These include allocation of risk in the dispute, avoidance of litigation costs, or beneficial access to technology from cross-licensing of the litigant's patents. Merck would be speculating as to why litigants would enter into settlements with large unjustified reverse payments. Question. Do you think these agreements stifle competition and prevent generic alternatives to your branded medications? Answer. Merck believes that the patent settlements it has made did not stifle competition nor unlawfully prevent generic alternatives to our patented medications. Patent settlement agreements in which a brand settles cases in a manner that allows a generic to enter the market prior to expiry of the brand's patents could actually accelerate patient access to lower cost alternatives. These settlements do not delay entry or cause the loss of any lawful competition because entry prior to the expiry of these patents would be unlawful infringement unless and until the generic manufacturers prevailed in court. Merck works within the statutory framework set by Hatch-Waxman and BPCIA to protect its intellectual property. We believe that patent holders have a valid right to enforce legitimate patents and that the courts are an appropriate venue to resolve such disputes. Our patents are a direct result of the investment we have made in R&D. When others seek to commercialize our innovations, Merck has engaged in litigation to enforce our patents. Merck is a strong supporter of bringing more generics to the market. It is important to remember that generics all started as a branded medication. A period of patent protection is provided for all new medicines as an incentive to research-based biopharmaceutical companies for the costly and risky research that is undertaken to develop them. Following the loss of patent protection, the medicines become low-cost generics that are available for many years, often decades into the future. Merck is proud that more than 40 million Americans annually benefit from our science in the form of generic medicines. Several of our discoveries--including cholesterol-lowering, heart disease, osteoporosis, and asthma treatments--are now widely available to a patient as generics, including some for about $20 per year, bringing billions of dollars in savings to consumers and the health care system. drug rebate rule Question. In January, the Department of Health and Human Services' (HHS) Office of Inspector General (OIG) promulgated a new regulation to remove regulatory safe harbor protections under the Anti-Kickback Statute (AKS) for rebates on prescription drugs rebates paid by manufactures to PBMs under Medicare Part D and for Medicaid managed care organizations (MCOs). The OIG proposal attempts to ban most rebates by eliminating their regulatory protections. The rule is predicted to increase net drug costs in its early years. The CMS actuaries estimate it would cost $196 billion over 10 years. Despite this high price tag, the beneficiary benefits are limited. The proposed rule notes that under the CMS Actuary's analysis, the majority of beneficiaries would see an increase in their total out- of-pocket payments and premium costs; reductions in total cost sharing will exceed total premium increases. I wanted to ask a question about the administration's rebate rule, which I understand that many of the drug manufacturers, and your main trade association, strongly support. According to an analysis of the rule by the Office of Actuaries at CMS, drug manufacturers are likely to initially retain 15 percent of the current rebates as higher net drug prices. Given that estimate, can you provide the committee with any assurances that prices will not increase under this proposed rule? Answer. Over time, we expect that list prices will go down if the misaligned incentives across the system are addressed. It is also important to note that if the rule is implemented, Medicare beneficiaries' out-of-pocket costs will be reduced, independent of any lowering of list prices, since their cost-sharing will be based on the net price. Nonetheless, we believe the rebate rule will align incentives in a way that will restrain list prices. ______ Questions Submitted by Hon. Sherrod Brown Question. According to an article recently published in the Journal of the American Medical Association, medical marketers spent nearly $30 billion dollars in 2016, up from $17 billion in 1997. Direct-to- Consumer (DTC) advertising had the biggest percentage increase: from $2.1 billion, or 11.9% of all medical marketing, in 1997 to $9.6 billion, or 32% of total spending, in 2016. Can you please provide what your ratio of spending on sales and marketing to research and development is today? Answer. In 2018, Merck incurred $9.8 billion in research and development costs globally, the vast majority of which was conducted in the U.S. Since 2010, Merck has invested nearly $70 billion in R&D to create new medicines and vaccines that address the greatest health challenges of our time--including antimicrobial resistance, Ebola, HIV, and cancer--to save and improve lives around the world. In 2018, Merck spent about $2.3 billion in the U.S. market on direct marketing and selling expenses. This number includes all sales and marketing expenses, including creative development of resources and headcount related to all marketing and sales activity in the U.S. market. price-gouging Question. Sanofi, as I understand it, has made a pledge to the public to limit its price increases to the national health expenditures growth projection. Would your company commit to a cap on annual price increases as part of your PhRMA membership criteria? Answer. In July 2018, Merck pledged to not increase the average net price across our portfolio by more than inflation annually. Question. What policies would you propose to help ensure lower launch prices for new drugs? Answer. Merck approaches pricing from the perspective of value. This approach looks at the value that a medicine provides through multiple lenses with the goal of reflecting its benefit to patients and to society, while at the same time paying an appropriate return on invested capital to our investors, to ensure that we are able to sustain R&D. While each individual situation varies based on factual circumstances and market dynamics, generally, we consider: Value provided to patients--to what extent does a new medicine or vaccine establish a new standard of care that has the potential to significantly extend and improve patient lives? Value provided to health-care systems--to what extent does a new medicine or vaccine reduce the costs associated with hospitalization and other costly complications of disease if not appropriately (or optimally) treated? Unmet need--does a new medicine or vaccine address a critically unmet medical need, where few or no treatments exist? Access--what is the ability of various customers around the world--including national, regional or local institutional payers, physicians, employers and patients--to pay for our products? R&D sustainability--given the long-term risk and cost of capital, can we appropriately compensate our investors to ensure continued investment in the kind of risky and capital- intensive research and development that will bring forward medically important breakthroughs? Competition--what are the costs of other treatments currently on the market relative to the value provided by Merck's products? We believe the proper objective should be that launch prices appropriately reflect the true value of the medicine and are not distorted by any misaligned incentives in Medicare Part D or any other sector. We believe the administration's proposed rebate safe harbor, and similar changes in commercial plans, would address the misaligned incentives in the marketplace that favor high list prices and high rebates in competitive markets. In addition, addressing the misaligned incentives for the 340B program would allow for more flexibility in list prices. transparency Question. In many of your testimonies, you mentioned that the current system of pharmacy benefit manager (PBM) back-end rebates do not rarely results in a scenario where the PBM passes on savings to consumers at the point of sale (POS). The administration recently proposed a rule to eliminate the anti-kickback statute safe harbor protections for these drug rebates. Do you agree that greater transparency should be required to understand how manufacturers and PBMs are negotiating prices and rebates to ensure that savings are passed down to beneficiaries? Answer. Yes. We believe there should be greater transparency of the financial arrangements between manufacturers and PBMs. In particular, we believe we must change the system to ensure that patients receive the benefit of the significant rebates and discounts that manufacturers like Merck pay to PBMs and plans. The administration's proposed rule is a positive step in that direction. Based on our initial assessment of the proposed rule, we believe that it will remove misaligned incentives within the system, drive more transparency in the system, and most importantly, lower beneficiaries' out-of-pocket costs. Question. Senator Thune asked if this administration rule would lead you to lowering list prices. Both of you answered that you would be likely to lower your prices. However, if this rule were finalized tomorrow as proposed, would any of your companies be required to lower the list price of any of your drugs? Answer. Under the proposed rule, there is no requirement to lower list prices. However, over time, we expect that our list prices will go down if the misaligned incentives across the system are addressed. It is also important to note that if the rule is implemented, Medicare beneficiaries' out-of-pocket costs will be reduced, independent of any lowering of list prices, since their cost-sharing will be based on the net price. Nonetheless, we believe the rebate rule will align incentives in a way that will restrain list prices. pbms Question. An Axios article from March 7, 2019 highlights the fact that, while ``pharmaceutical companies put a lot of the blame for high drug prices on pharmacy benefit managers,'' many large pharmaceutical companies ``rely on PBMs to manage their own health-care benefits.'' In your role as an employer, does your company contract with a pharmaceutical benefit manager (PBM) to administer the prescription drug benefits for your employees and negotiate lower drug costs on your behalf? For those of you who do use a PBM to help manage the prescription drug benefit for your employees, how do you utilize the rebates your PBM negotiates to lower health care costs or drug costs for your employee plans and what does your company do with that savings? Specifically, do the savings go toward lowing premiums? For those of you who do use a PBM to help manage the prescription drug benefit for your employees, does your PBM offer point-of-sale rebates to your employees? Answer. Merck offers a generous health care benefit for our 24,000 U.S. employees. There is no deductible for medications covered under our pharmacy benefit, and employees never have to pay more than $50 for a retail prescription for a covered medication, and in most cases pay less. We contract with a PBM for management of the prescription drug benefits for our employees, and the benefit does not offer point-of- sale rebates to our employees. Merck uses savings generated by the PBM on rebates to lower overall costs for employees while ensuring low out- of-pocket costs. ______ Questions Submitted by Hon. Sheldon Whitehouse Question. Please describe any policy changes you support that would result in your company lowering the list prices of its drugs. Answer. Over time, we expect that our list prices will go down if the misaligned incentives across the system are addressed. Nonetheless, we believe the rebate rule will align incentives in a way that will restrain list prices. As we stated when we reduced the list price of several of our products in July 2018, we have continued to look for opportunities to reduce our list prices. We think the proposed rule would help create those opportunities, but it can't happen overnight. All of the players in the ecosystem will need to adjust to the new model. If the proposed rule is implemented as written, it would only apply to our contracts with PBMs and health plans for Medicare Part D and Managed Medicaid. If PBMs and health plans maintain the rebate model in the commercial market, we would still have commercial contracts based on rebates, which would be subject to the existing constraints to lowering list price. We also would still need a mechanism to revalue drug in the distribution channel in a financially viable manner. Question. How much does your company's research and development portfolio rely on taxpayer-funded research conducted by the National Institutes of Health (NIH)? How many of your company's products are based, at least in part, on NIH research, and how many are the result of research funded solely by your company? Answer. The U.S. leads the world in biomedical research thanks to a robust biomedical ecosystem comprised of important and unique contributions from the National Institutes of Health (NIH), academic institutions, and the biopharmaceutical industry. Historically, the NIH's focus has been on basic biomedical science and research concerning public health (including in the recent budget funding for drug and alcohol abuse prevention, reducing health-care disparities, and other important causes). Through this basic research, NIH seeks to understand the fundamental biological processes and leverage that understanding to determine which processes are involved in the development and progression of disease. There is significant basic research that in some respects contributes to all new medicines. Most of this is considered ``pre-competitive'' since the individual contributions are in themselves too small or too broad to lead directly to a new therapy, which takes considerable work to invent and develop. Merck also conducts basic research. However, where we use intellectual property that others have created, we are diligent in recognizing and agreeing on terms to use that property (including financial compensation), which may include with agencies of the U.S. government such as NIH. After this stage of basic research, our company's further role is to then engage in the most risky and costly part of discovery--to invent something that's never existed in the history of the world that will alter the targets that come from basic research and unlock treatments and cures for disease. This invention is then followed by extensive clinical trial programs to demonstrate safety and effectiveness. On occasion, we will rely on work by government agencies that is more advanced; however, we take the same approach of respecting intellectual property rights and agreeing on terms of use of that property. For example, Merck, along with Instituto Butantan, has licensed certain rights from National Institute of Allergy and Infectious Diseases (NIAID), part of NIH, for the development of live attenuated tetravalent vaccines (LATV). All parts of the ecosystem are needed to continue to lead in biomedical research: the portion of NIH's entire $33 billion budget that it devoted to biomedical research in 2017 as well as the $70 billion the biopharmaceutical industry spent in 2017--$10 billion of which was spent by Merck--to invent and bring to market new treatments and cures. Question. In each of the last 5 years, how much has your company spent on research and development versus the advertising and marketing of your products? Answer. In 2018, Merck incurred $9.8 billion in research and development costs globally, the vast majority of which was conducted in the U.S. Since 2010, Merck has invested nearly $70 billion in R&D to create new medicines and vaccines that address the greatest health challenges of our time--including antimicrobial resistance, Ebola, HIV, and cancer--to save and improve lives around the world. In 2018, Merck spent about $2.3 billion in the U.S. on direct marketing and selling expenses. This number includes all sales and marketing expenses, including creative development of resources and headcount related to all marketing and sales activity in the U.S. market. For the remaining years, we spent the following: In 2017, Merck invested $10.3 billion in R&D and $2.5 billion in U.S. marketing and selling expenses. In 2016, Merck invested $10.3 billion in R&D and $2.5 billion on U.S. marketing and selling expenses. In 2015, Merck invested $6.8 billion in R&D and $2.4 billion on U.S. marketing and selling expenses. In 2014, Merck invested $7.3 billion in R&D and $2 billion on U.S. marketing and selling expenses. Question. During the hearing, you mentioned that your company would be likely to lower the list prices of its drugs if the recent proposal by the Trump administration to change the current system of rebates was extended to the private market. If the policy was extended to the private market, how large would the list price reductions be relative to the size of the rebates your company is currently providing? Answer. It is hard to predict an exact amount of list price reduction if the rule were implemented as described. However, we believe that removing the misaligned incentives from the system should result in downward pressure on list prices. It is also important to understand that different purchasers receive different levels of discounts, based on the access provided for patients. So, there is not a uniform ``rebate amount'' that could reduce the list price. Moreover, we expect that the robust negotiations that occur today will continue in the highly competitive Part D market, and we expect to realize the same level of net price that we do today. In fact, we expect that there could be additional pricing pressure under the new system, which could lead to lower net prices. Question. How will this proposal affect how your company sets the list prices for new drug products? Answer. Merck approaches pricing from the perspective of value. This approach looks at the value that a medicine provides through multiple lenses with the goal of reflecting its benefit to patients and to society, while at the same time paying an appropriate return on invested capital to our investors, to ensure that we are able to sustain R&D. While each individual situation varies based on factual circumstances and market dynamics, generally, we consider: Value provided to patients--to what extent does a new medicine or vaccine establish a new standard of care that has the potential to significantly extend and improve patient lives? Value provided to health-care systems--to what extent does a new medicine or vaccine reduce the costs associated with hospitalization and other costly complications of disease if not appropriately (or optimally) treated? Unmet need--does a new medicine or vaccine address a critically unmet medical need, where few or no treatments exist? Access--what is the ability of various customers around the world--including national, regional or local institutional payers, physicians, employers and patients--to pay for our products? R&D sustainability--given the long-term risk and cost of capital, can we appropriately compensate our investors to ensure continued investment in the kind of risky and capital- intensive research and development that will bring forward medically important breakthroughs? Competition--what are the costs of other treatments currently on the market relative to the value provided by Merck's products? We do not expect this approach to change based on the Trump administration's proposed rule. Question. If the proposal is finalized and not extended to the private market, will your company make any list price reductions? If so, how large would the reductions be relative to the size of the rebates your company is currently providing? Answer. We expect that the robust negotiations that occur today will continue in the highly competitive Part D and commercial markets, and we expect to realize the same level of net price that we do today. In fact, we expect that there could be additional pricing pressure under the new system, which could lead to lower net prices, but predicting the size of any such reductions is difficult. ______ Question Submitted by Hon. Maggie Hassan Question. In June of 2018, the Medicaid and CHIP Payment and Access Commission (MACPAC) unanimously recommended under Recommendation 1.1 in their annual report to Congress that Congress remove the statutory requirement that manufacturers blend the average manufacturer price (AMP) of a brand drug and its authorized generic.\13\ --------------------------------------------------------------------------- \13\ MACPAC. ``Improving Operations of the Medicaid Drug Rebate Program,'' https://www.macpac.gov/wp-content/uploads/2018/06/Improving- Operations-of-the-Medicaid-Drug-Rebate-Program.pdf. This requirement created an unintended loophole. Rather than use the price of the authorized generic, drug companies can sell its authorized generic to a corporate subsidiary at an artificially lower price and use that lower price to bring down the AMP, which in turn --------------------------------------------------------------------------- lowers the rebate obligation. Does your company engage in this practice? Has your company ever engaged in this practice in the past? Answer. No. Merck does not engage in the practice of selling authorized products to a subsidiary and then blending the pricing data for the products. Merck does engage with third parties who act as our authorized generic partners. Merck has disclosed the methodology used to account for these transactions in AMP to CMS. ______ Questions Submitted by Hon. Catherine Cortez Masto Question. As a portion of your revenue, for what percentage of the drugs in your portfolio do you offer no rebates? Based on the drugs in your pipeline, do you foresee that portion growing? For those drugs is your list price equal to your net price? Answer. Since Merck's entire product portfolio is covered within at least one government program that requires a mandated rebate or discount (such as Medicaid, 340B, Federal Supply Schedule), there are no Merck products that are not rebated or discounted. Merck also offers voluntary rebates or discounts on many of its products. We would expect similar rebates and discounts to be paid for our drugs in the pipeline, barring fundamental changes in the marketplace. Question. Do you invest more in R&D than you generate in US sales revenue? Please include specific figures. Answer. In 2018, Merck incurred $9.8 billion on research and development costs globally, the vast majority of which was conducted in the U.S. Since 2010, Merck has invested nearly $70 billion in R&D to create new medicines and vaccines that address the greatest health challenges of our time--including antimicrobial resistance, Ebola, HIV, and cancer--to save and improve lives around the world. In 2018, Merck had $18.2 billion in U.S. sales revenue. Question. Do you invest more in R&D than you spend on marketing and administration? What company functions do you consider to be included in administration? Please include specific figures. Answer. In 2018, Merck incurred $9.8 billion in research and development costs globally, the vast majority of which was conducted in the U.S. Since 2010, Merck has invested nearly $70 billion in R&D to create new medicines and vaccines that address the greatest health challenges of our time--including antimicrobial resistance, Ebola, HIV, and cancer--to save and improve lives around the world. In 2018, Merck spent about $10.1 billion on marketing, selling, and administration globally ($2.6 billion of which is directly attributed to the U.S. market). This number includes all sales and marketing expenses, including creative development of resources and headcount related to all marketing and sales activity, as well as administrative expenses associated with business support functions, including information technology, human resources, facilities, finance, legal, and others. Question. Do you invest more in R&D than you spend on marketing and sales? What company functions do you consider to be included in sales? Please include specific figures. Answer. In 2018, Merck incurred $9.8 billion on research and development costs globally, the vast majority of which was conducted in the U.S. Since 2010, Merck has invested nearly $70 billion in R&D to create new medicines and vaccines that address the greatest health challenges of our time--including antimicrobial resistance, Ebola, HIV, and cancer--to save and improve lives around the world. In 2018, Merck spent about $6.9 billion on direct marketing and selling expenses globally ($2.3 billion of which is directly attributable to the U.S. market). This number includes all sales and marketing expenses, including creative development of resources and headcount related to all marketing and sales activity in the U.S. market. Question. Why do you advertise for the drugs you manufacture? What factors do you consider in choosing which drugs you advertise? Answer. Merck believes that direct-to-consumer (DTC) advertising can be an important and helpful way to inform patients about diseases that may be relevant to them and therapeutic options they may want to discuss with their physician. Data demonstrate that DTC can have a positive impact on patient health in terms of diagnosis, treatment, and adherence to prescribed therapies. We recognize that DTC is one channel amongst many to help educate patients. Print materials, telephone, websites, and other channels are also used to provide more in-depth information to patients. The ultimate decision to prescribe a product for any specific patient remains with the physician following discussion with their patient. Merck adheres to FDA regulations and guidelines governing DTC promotion and has a long-standing policy to voluntarily submit new DTC broadcast advertising campaigns to FDA for pre-review. Merck also follows the PhRMA Guiding Principles for DTC Advertisements About Prescription Medicines. We are currently considering what additional information we can make available to consumers to ensure that they can make informed health care decisions. ______ Prepared Statement of Richard A. Gonzalez, Chairman and Chief Executive Officer, AbbVie Inc. I am Richard Gonzalez, and I am the chairman and chief executive officer of AbbVie, a company dedicated to developing new innovative medicines for some of healthcare's most challenging diseases, such as cancer, Alzheimer's, viral infections, and auto-immune diseases. Since our inception in 2013, AbbVie has invested approximately $50 billion in pursuit of that goal. However, because we are tackling medicine's most challenging problems, solutions do not come easily or without significant risk. Where we have succeeded, we have been able to provide cures for fatal diseases like hepatitis C and significantly alter the disease progression for certain cancers, lessening the burden of illness on patients and the health-care system. This is what the 30,000 employees of AbbVie are dedicated to doing. We agree that access to lifesaving medicines is a critical issue and we look forward to sharing our perspectives with you. There is no one solution to this complex issue, but AbbVie is open to working with the committee on how we can commit our resources to better partner in your efforts to address pharmaceutical pricing and access. AbbVie and the rest of our industry must play a role in solving these issues and be prepared to work together with the insurance industry, the administration and you to find a better path forward for American patients. My remarks today will focus on one aspect of this inquiry--the Medicare Part D benefit design, which even after pharmaceutical list prices are lowered, still contributes to making innovative therapies cost-prohibitive for Medicare patients. In general, the Medicare Part D program has worked well. Its market-based structure and utilization of formularies encourages competitive price discounts that have yielded significant savings to the government since the Part D benefit was established in 2006. However, despite these cost savings, Part D patients' out-of-pocket costs have significantly increased. Some would blame that solely on high drug prices, and we agree that price should certainly be part of the discussion. But it's also important to acknowledge that science has enabled us to advance the standard of care far beyond what was possible when the Part D benefit was designed. Many of today's specialty medicines offer major advances in treating or curing serious chronic or life-threatening conditions and save significant amounts of money for the health-care system by decreasing overall health-care costs, yet these therapies are also costly. Due to the structure of the Part D benefit design, patients are charged out-of-pocket costs on a medicine's list price which does not reflect the market-based rebates that Medicare receives. We are encouraged by the proposed rule that would reflect manufacturer discounts in patients' Part D out-of-pocket payments. This is an important step in the right direction, but we believe more must still be done to help Part D patients. Let me give you a recent real-world example that demonstrates the challenge with the current Part D benefit design and why the focus solely on list prices does not fully address the access challenges. An uncured hepatitis C infection leads to downstream medical costs for surgery, chemotherapy, and radiation for patients who progress to needing a liver transplant or having liver cancer. Today we can cure hepatitis C with drugs. This cure is highly cost-effective for the overall health-care system. In 2017, AbbVie launched Mavyret, a highly effective cure for HCV. At the time, the list prices for the competitive alternatives were as high as $94,500 for their most commonly prescribed treatment duration. We launched Mavyret at a list price that is 72 percent lower. But even though we cut the list price of an HCV cure for most patients by 72 percent, Medicare Part D patients' out-of-pocket obligations are still too high for many patients to access this medicine. We believe it is important that discussions about access and affordability include a focus on how to alleviate Medicare Part D out- of-pocket burdens above and beyond just lowering list prices. We are prepared to step up and discuss how companies like ours can shoulder more of the burden of a patient's out-of-pocket expenses, as we do in other areas covered by commercial insurance. Additionally, we believe the discussion should also include the possibility of Medicare Part D beneficiaries being able to purchase insurance (as they do in other parts of the Medicare program) to cover more of their out-of-pocket expenses. We believe AbbVie, the rest of the pharmaceutical industry and insurance providers should come together with the administration and you to work toward solutions that make life-changing medicines more affordable to Part D beneficiaries. I can assure you AbbVie is committed to doing its part, and we look forward to working with you. ______ Questions Submitted for the Record to Richard A. Gonzalez \1\ --------------------------------------------------------------------------- \1\ Please note that these responses were prepared by and are from AbbVie Inc. --------------------------------------------------------------------------- Questions Submitted by Hon. Chuck Grassley Question. The Department of Health and Human Services' proposed rule, ``Fraud and Abuse; Removal of Safe Harbor Protection for Rebates Involving Prescription Pharmaceuticals and Creation of New Safe Harbor Protection for Certain Point-of-Sale Reductions in Price on Prescription Pharmaceuticals and Certain Pharmacy Benefit Manager Service Fees,'' envisions that drug manufacturers will offer up-front discounts rather than the back-end rebates that are now commonly provided. Some observers argue that a 1996 court case called into question whether manufacturers could offer up-front discounts, resulting in today's rebate-based system. I've heard differing opinions as to whether the issues related to the initial court case are still relevant. If the HHS proposed rule is finalized, can you assure the Committee that your company will offer up-front discounts? If not, why? Please describe how you expect your company to respond to the HHS proposed rule to eliminate safe harbor protection for back-end rebates in Medicare Part D that is referenced above if it is finalized. Assuming you are confident that antitrust laws do not prevent your company from offering up-front discounts, specifically, do you envision that your company lowers the list price of a drug to the current after- rebate net price, offer discounts equal to the current rebate amount, or a combination of both? Answer. There has been significant discussion over the past several months about proposals to eliminate rebates from Medicare Part D, Medicaid, and the commercial market culminating in the administration's publication of a proposed rule to ``expressly exclud[e] from safe harbor protection under the Anti-Kickback Statute (AKS) rebates on prescription drugs paid by manufacturers to pharmacy benefit managers (PBMs), Part D plans, and Medicaid managed care organizations. The proposal would create a new safe harbor protecting discounts offered to patients at the pharmacy counter. Finally, the proposal would create new safe harbor protection for fixed fee services arrangements between manufacturers and PBMs.'' AbbVie is encouraged by the goals of the proposed rule to ensure manufacturer discounts are reflected in and reduce patient cost sharing under Part D. While we believe the rule is an important step in the right direction, we also believe more should be done to help reduce the out-of-pocket cost burden on Medicare Part D patients. As for what the elimination of rebates might mean to the overall health-care system or pharmaceutical companies, it is premature to comment on these items until the administration's rule is finalized, implementation timelines are solidified, and there are specific details regarding how a new system without rebates will be structured and function. Question. To what extent are the back-end rebates your company currently offers contingent on the amount of market share realized for your drugs as a result of Part D plan formulary placement and other techniques? Answer. AbbVie does not have market-share based arrangements. Question. Please provide a breakdown of percentage of sales that go to each payer (including Medicare, Medicaid, private pay, other) and a similar percentage by volume of the total number of each drug compared to total volume. Please provide this data for the most recent year available. Answer. In 2018, on a U.S. dollars basis approximately 68 percent of AbbVie's U.S. net sales were to commercial payers and approximately 32 percent were to government payers. AbbVie does not maintain this information on a volume basis across all products. For Humira, AbbVie's top product for sales, on a volume basis in the U.S. approximately 68 percent of Humira sales were to commercial payers and approximately 32 percent were to government payers. But on a U.S. dollars basis, approximately 83 percent of Humira sales were to commercial payers and only approximately 17 percent were to government payers. Question. Do your companies hire consultants or lobbyists to promote products at State Medicaid Pharmacy and Therapeutics Committees? To whom do you disclose advocacy activities surrounding State Medicaid programs, if at all? Answer. AbbVie does not hire consultants or lobbyists to promote products at State Medicaid Pharmacy and Therapeutics Committees. We adhere to individual State's laws and regulations with respect to advocacy disclosures. Question. Please describe how the costs of patient assistance programs are accounted for within your company's financial statements. Please also describe the types of market information, such as prescribing and use patterns, that your company collects from different types of patient assistance programs and patient hub services. Answer. The AbbVie Patient Assistance Program, which provides free drug to eligible individuals, falls under the administration portion of SG&A. AbbVie's commercial co-pay assistance costs are deducted from gross sales. The information that AbbVie collects through its patient support services varies by products but may include demographic information, diagnosis codes and prescription information, insurance information, and claim information. AbbVie collects a more limited set of this data through its Patient Assistance Program in order to assess patients for eligibility and distribute medication to patients. Question. Please provide a list of all contributions since January 1, 2014, that your company has made to any tax exempt organizations working on issues related to drugs within your product lines, including but not limited to patient groups, disease awareness groups, medical or professional societies, universities or hospitals, industry associations or leagues. for each contribution, please provide the name of the organization that received the donation, the date the donation was made, the amount of the donation, and a description of the purpose of the contribution (i.e., was the contribution for the general fund, a specific purpose to a specific program, or continuing medical education). Please also note whether the contribution was unrestricted or restricted; if it was restricted, please explain all restrictions. Finally, if your company maintains a foundation or other separate charitable arm, please provide the name of all such entities, and list all donations made from that entity or entities. Answer. Attached as Exhibit 1 to this response is a list of all contributions AbbVie has made in the following categories from January 1, 2014 through December 31, 2018: (1) charitable donations to non- profit organizations; (2) donations for patient education and disease state diagnosis, treatment, and awareness; (3) educational grants; (4) fellowships and scholarships; and (5) sponsorships of non-profit organizations' events. The AbbVie Foundation is a separate non-profit entity that makes charitable donations and grants. Attached as Exhibit 2 is a list of all charitable donations and grants made by The AbbVie Foundation from January 1, 2014 through December 31, 2018. Question. Pay-for-delay agreements cost consumers and taxpayers billions in higher drug costs every year. The FTC has gone after drug companies that enter into these settlements where the brand pays the generic company to keep its lower cost alternative off the market. I'm the lead Republican sponsor of S. 64, the ``Preserve Access to Affordable Generics and Biosimilars Act,'' which would help put an end to these deals. Do you agree that these pay-off agreements keep drug costs high for patients because they delay competition? Has your company ever entered into these kinds of settlements with a generic company? Answer. ``Pay-for-delay'' is not a self-defining phrase. With respect to the term ``pay,'' patent litigation settlements, like all litigation settlements, involve compromise in which both sides believe they are getting value from the resolution. There is no definition explaining the circumstances under which that value would implicate the term ``pay'' in ``pay-for-delay'' for purposes of these questions. And with respect to ``delay'' virtually all patent settlements provide for the generic competitor to enter the market before the expiration of the patent at issue. So if the alternative resolution of a patent lawsuit would be the innovator company continuing to enforce its patent until expiration, then such a settlement, no matter what value is exchanged, would actually accelerate competition, not delay it. Question. Do you support the pay-for-delay bill? Answer. AbbVie supports the goals of the Preserve Access to Affordable Generics and Biosimilars Act and would likely support the bill upon clarification that enforcement only applies to agreements after the date of enactment. rebate traps/walls Question. I'm increasingly concerned about the effect of so-called ``rebate traps'' or ``rebate walls'' on patients' access to quality, lower-cost medicine. I understand there is ongoing litigation challenging these practices as anti-competitive. Does your company engage in the bundling of rebates over multiple products? If so, why? And what benefit does the consumer gain from that? Does your company view these practices as anticompetitive or harmful to patients' access to quality, lower cost medicine? Answer. Rebates are a form of price competition that results from the aggressive negotiations that occur between health plans (and their representative PBMs) and pharmaceutical companies to provide patients with access to medicines and treatments that can best help patients manage their medical conditions. Question. If a policy were adopted to eliminate rebates, or to require that rebate savings be passed on to the consumer, would that in and of itself solve the issue of rebate ``traps'' and ``walls''? And would consumers benefit from such a policy? Answer. There has been significant discussion over the past several months about proposals to eliminate rebates from Medicare Part D, Medicaid, and the commercial market culminating in the administration's publication of a proposed rule to ``expressly exclud[e] from safe harbor protection under the Anti-Kickback Statute (AKS) rebates on prescription drugs paid by manufacturers to pharmacy benefit managers (PBMs), Part D plans, and Medicaid managed care organizations. The proposal would create a new safe harbor protecting discounts offered to patients at the pharmacy counter. Finally, the proposal would create new safe harbor protection for fixed fee services arrangements between manufacturers and PBMs.'' AbbVie is encouraged by the goals of the proposed rule to ensure manufacturer discounts are reflected in and reduce patient cost sharing under Part D. While we believe the rule is an important step in the right direction, we also believe more should be done to help reduce the out-of-pocket cost burden on Medicare Part D patients. As for what the elimination of rebates might mean to the overall health care system or pharmaceutical companies, it is premature to comment on these items until the administration's rule is finalized, implementation timelines are solidified, and there are specific details regarding how a new system without rebates will be structured and function. drug pricing Question. When setting the list price of a drug, does your company consider regulatory costs or compliance? If so, how specifically do those factors affect the list price of a drug? Please provide at least one specific example, if applicable, from your current product portfolio. Answer. AbbVie does not consider regulatory costs or compliance when considering the list price of a medicine. Question. When setting the list price of a drug, does your company consider the risk of liability or litigation? If so, how specifically do those factors affect the list price of a drug? Please provide at least one specific example, if applicable, from your current product portfolio. Answer. AbbVie does not consider the risk of liability or litigation when considering the list price of a medicine. ______ Questions Submitted by Hon. Pat Roberts Question. What role do you see value-based arrangements (VBAs) playing in the effort to reduce prescription drug costs? What potential do these arrangements have to find the ``sweet spot'' between controlling costs to patients and encouraging innovation of new drugs? How can VBAs help lower what patients pay out-of-pocket? Can Congress do more to allow for and encourage the use of VBAs? Answer. Value-based arrangements can be an effective and market- based solution to managing overall health-care costs when driven by patient outcomes. Studies have found that 38 percent of payers with outcomes-based contracts experience improved patient outcomes and 33 percent experience plan health-care cost savings. Additionally, plans with outcomes-based contracts have been found to have a 28 percent lower patient co-payment. All of these factors work towards moving payment for prescription medicines away from volume-based approaches to value-based models in a manner that appropriately balances patient access with the appropriate use of medications to lower overall health- care costs. At AbbVie, we believe all our products provide value to patients and the larger health-care system and are interested in the possibilities that could arise through value-based contracting. To further foster value-based arrangements, we support the reforms included in the Patient Affordability, Value and Efficiency (PAVE) Act, introduced by Senators Cassidy (R-LA) and Warner (D-VA). ______ Questions Submitted by Hon. John Cornyn Question. We continue to hear that rebates negotiated off of the list price of a drug are both good and bad. Pharmacy benefit managers and plans have argued that rebates are used to lower premiums across the board and that it is the best way to seek a price concession on otherwise expensive drugs. Your industry argues that these payers are insisting on higher rebates that can only be achieved by raising list prices. But patients often lose under this system, with out of pocket costs being tied to list price. Insulin patients appear to be routinely impacted by this perversity in the system. Please explain to the committee how your company would reduce list prices if rebates were no longer a part of the equation? What assurance can you provide that you would in fact lower your prices? Answer. There has been significant discussion over the past several months about proposals to eliminate rebates from Medicare Part D, Medicaid, and the commercial market culminating in the administration's publication of a proposed rule to ``expressly exclud[e] from safe harbor protection under the Anti-Kickback Statute (AKS) rebates on prescription drugs paid by manufacturers to pharmacy benefit managers (PBMs), Part D plans, and Medicaid managed care organizations. The proposal would create a new safe harbor protecting discounts offered to patients at the pharmacy counter. Finally, the proposal would create new safe harbor protection for fixed fee services arrangements between manufacturers and PBMs.'' AbbVie is encouraged by the goals of the proposed rule to ensure manufacturer discounts are reflected in and reduce patient cost sharing under Part D. While we believe the rule is an important step in the right direction, we also believe more should be done to help reduce the out-of-pocket cost burden on Medicare Part D patients. As for what the elimination of rebates might mean to the overall health care system or pharmaceutical companies, it is premature to comment on these items until the administration's rule is finalized, implementation timelines are solidified, and there are specific details regarding how a new system without rebates will be structured and function. Question. What actions should be taken to ensure that patients are actually seeing the benefits of lower out-of-pocket costs? Answer. Providing discounts to the patient at the point of sale is an effective way of ensuring that patients can see lower out-of-pocket costs. However, this is just the start. AbbVie believes that more must be done. The Medicare Part D benefit design contributes to making innovative therapies cost-prohibitive for Medicare patients because patients are charged out-of-pocket costs based on a medicine's list price, which does not reflect the rebates that Medicare receives. AbbVie believes it is important to alleviate the burdens that patients face due to Medicare Part D out-of-pocket costs. AbbVie supports solutions like a patient out-of-pocket cap in Part D and smoothing patient out-of-pocket payments over a full year, so patients have some predictability with respect to their out-of-pocket costs. In addition, AbbVie is prepared to step up and discuss how companies like ours can shoulder more of the burden of a patient's out- of-pocket expenses. As policymakers consider the impact of addressing out-of-pocket costs in Medicare Part D, questions may arise around whether it will lead to unnecessary utilization and wasteful spending. for specialty medicines, increased utilization should not be misunderstood as unnecessary or wasteful. Part D plans have tools, like step therapy requirements for patients to first try lower cost alternatives before a specialty medicine would be covered and prior authorization requirements before a specialty medicine would be covered, to manage the utilization of the majority of higher cost specialty medicines. These tools ensure patients try a less costly medication first and have met the clinical criteria for taking the specialty drug prescribed and serve the function that an out-of-pocket cost obligation on patients might serve to prevent unnecessary use. Question. If rebates are driving high list prices for drugs as drug manufacturers' claim, why do you think that Part B drugs, which have no PBM rebates, are also seeing significant price increases? Whose fault is that? Answer. Manufacturers do offer rebates on Part B products in the commercial market. Those rebates are included in the calculation of the Part B Average Sales Price (ASP) and are therefore reflected in the price Medicare pays for Part B drugs. AbbVie does, however, recognize that increased competition in Part B could lead to additional savings and welcomes the opportunity to engage in policy discussions that seek to increase competition in Part B. ______ Question Submitted by Hon. Michael B. Enzi Question. The Food and Drug Administration's drug review process is known to many as the ``gold standard'' for evaluating medical products. I've long thought that it is critical that we maintain public confidence in their ability to ensure that drugs are safe and effective. There is a perception among some, however, that biosimilars might not be as safe as their reference products. That perception can undermine patient and provider confidence. Do you believe that when FDA approves a biosimilar, providers can be confident that it is safe and effective? Answer. Consistent with the US regulatory scheme for biosimilars, we recognize that FDA-approved biosimilars are highly similar to the reference product with no clinically meaningful differences. Unlike small molecule generics, however, biosimilars do not contain the identical active ingredient as their reference products and biosimilars are not substitutable at the pharmacy for the reference drug absent an FDA designation of interchangeability. As FDA has acknowledged, multiple exposures to slightly different biologics can prime the immune system to recognize subtle differences in structural features between products, triggering or increasing the overall immune response. Consequently, a finding of interchangeability must be supported by additional data demonstrating that the biosimilar is ``expected to produce the same clinical result in any given patient,'' and that there is no risk to patients associated with alternating or switching between the biosimilar and the reference product. There is no requirement that two biosimilars found to be interchangeable with a single reference product must show that it is safe and effective to switch between the two interchangeable biosimilars, even though in practice this is likely to happen in the marketplace if biosimilars are treated like generic drugs. Different biosimilar products each found interchangeable with a single reference product will have subtle structural differences from each other. Indeed, there may be more structural differences--or different types of structural differences-- between the two biosimilar products than between either biosimilar and the reference product. As such, without clinical data assessing the effects of switching between two biosimilars of the same reference, there is no evidence to scientifically justify interchangeability or automatic substitution between them. AbbVie has raised this concern with FDA at a 2018 Part 15 Hearing held by the agency on the subject of biosimilarity and interchangeability. These fundamental distinctions between small molecule and biologic medicine regulation should not change the perception that FDA-approved biosimilars are safe and effective, but they are central to any understanding of the biologics market and the appropriate use of these complex products. ______ Questions Submitted by Hon. Todd Young re-evaluating business strategies in foreign countries Question. Since taking office, President Trump has made reducing drug prices one of his highest priorities--and has repeatedly spoken about his frustration with the U.S. subsidizing the costs of pharmaceuticals for the rest of the world. He has gone so far as to issue proposals, like the International Pricing Index (IPI) Model, in an attempt to bring down prescription drug prices. With the increased scrutiny of the industry and of the drug supply chain as a whole in the United States, have any of your companies re- evaluated your business strategy in foreign countries? If not, then why? If a proposal, like IPI, were implemented, would it force your companies to potentially ``walk away from the negotiating table when other countries demand low prices subsidized by America's seniors,'' as HHS Senior Advisor for Drug Pricing Reform John O'Brien has said? Answer. The focus on U.S. versus ex-U.S. prices for pharmaceuticals creates an erroneous impression that medicines are the major driver of U.S. health care cost growth--ignoring that medicines account for a small share of overall health spending. Many countries impose price controls and restrict access to medicines in order to contain costs. That is not the system we have here in the United States; nor should it be. The U.S. fosters innovation and leads the world in drug discovery and development with PhRMA members conducting nearly 80 percent of their R&D in the United States. Importing or referencing price controls used in other countries in the U.S. would challenge the innovation model in a country the size of the U.S. The U.S. relies on its competitive marketplace to manage costs, while encouraging the development of new therapies. Because of the ecosystem that exists in the U.S., patients enjoy access to innovative medicines far earlier than patients in countries with centralized price controls. Furthermore, most crosscountry comparisons focus solely on the list prices of medicines and exclude from calculations the steep discounts that are required in U.S. public programs such as Medicaid and the rebates negotiated by insurers and pharmacy benefit managers in Medicare Part D and the commercial market. In addition, these comparisons often only include the list prices of brand-name medicines even when lower-cost generic versions are available and widely used. Instead of referencing price, AbbVie recommends policymakers focus on reforms that address foreign freeloading in new trade agreements or increasing enforcement of current agreements. We support enhancements to trade agreements to balance share of investment costs. The United States-Mexico-Canada Agreement (USMCA), while not yet implemented, contains improvements in intellectual property protections as well as provisions requiring transparency in pricing and reimbursement mechanisms. These elements are critical to ensuring trading partners like Mexico and Canada appropriately value innovation, allowing innovative biopharmaceutical companies to continue bringing new medicines to the market. Question. What are some of your ideas on how we can ensure Americans aren't shouldering the full cost of pharmaceuticals? Answer. Providing discounts to the patient at the point of sale is an effective way of ensuring that patients can see lower out-of-pocket costs. However, this is just the start. AbbVie believes that more must be done. The Medicare Part D benefit design contributes to making innovative therapies cost-prohibitive for Medicare patients because patients are charged out-of-pocket costs based on a medicine's list price, which does not reflect the rebates that Medicare receives. AbbVie believes it is important to alleviate the burdens that patients face due to Medicare Part D out-of-pocket costs. AbbVie supports solutions like a patient out-of-pocket cap in Part D and smoothing patient out-of-pocket payments over a full year, so patients have some predictability with respect to their out-of-pocket costs. In addition, AbbVie is prepared to step up and discuss how companies like ours can shoulder more of the burden of a patient's out- of-pocket expenses. As policymakers consider the impact of addressing out-of-pocket costs in Medicare Part D, questions may arise around whether it will lead to unnecessary utilization and wasteful spending. for specialty medicines, increased utilization should not be misunderstood as unnecessary or wasteful. Part D plans have tools, like step therapy requirements for patients to first try lower cost alternatives before a specialty medicine would be covered and prior authorization requirements before a specialty medicine would be covered, to manage the utilization of the majority of higher cost specialty medicines. These tools ensure patients try a less costly medication first and have met the clinical criteria for taking the specialty drug prescribed and serve the function that an out-of-pocket cost obligation on patients might serve to prevent unnecessary use. foreign countries' pricing and reimbursement Question. President Trump and Secretary Azar have both repeatedly described their frustrations with ``foreign freeloading'' of U.S. drugs in the last year. ``When foreign governments extort unreasonably low prices from U.S. drug makers, Americans have to pay more to subsidize the enormous cost of research and development. . . . It's unfair and it's ridiculous, and it's not going to happen any longer.'' Do you agree that because of foreign countries' pricing and reimbursement systems, U.S. patients and innovators are shouldering the burden for financing medical advances? How do foreign countries' pricing and reimbursement systems affect our prescription drug costs? Are foreign governments taking note of the concerns being raised by the Trump administration and have they responded in any way? Has there been any noticeable change in any of our trade agreements since these concerns have been raised by the Trump Administration? Answer. The focus on U.S. versus ex-U.S. prices for pharmaceuticals creates an erroneous impression that medicines are the major driver of U.S. health-care cost growth--ignoring that medicines account for a small share of overall health spending. Many countries impose price controls and restrict access to medicines in order to contain costs. That is not the system we have here in the United States; nor should it be. The U.S. fosters innovation and leads the world in drug discovery and development with PhRMA members conducting nearly 80% of their R&D in the United States. Importing or referencing price controls used in other countries in the U.S. would challenge the innovation model in a country the size of the U.S. The U.S. relies on its competitive marketplace to manage costs, while encouraging the development of new therapies. Because of the ecosystem that exists in the U.S., patients enjoy access to innovative medicines far earlier than patients in countries with centralized price controls. Furthermore, most crosscountry comparisons focus solely on the list prices of medicines and exclude from calculations the steep discounts that are required in U.S. public programs such as Medicaid and the rebates negotiated by insurers and pharmacy benefit managers in Medicare Part D and the commercial market. In addition, these comparisons often only include the list prices of brand-name medicines even when lower-cost generic versions are available and widely used. Instead of referencing price, AbbVie recommends policymakers focus on reforms that address foreign freeloading in new trade agreements or increasing enforcement of current agreements. We support enhancements to trade agreements to balance share of investment costs. The United States-Mexico-Canada Agreement (USMCA), while not yet implemented, contains improvements in intellectual property protections as well as provisions requiring transparency in pricing and reimbursement mechanisms. These elements are critical to ensuring trading partners like Mexico and Canada appropriately value innovation, allowing innovative biopharmaceutical companies to continue bringing new medicines to the market. medicaid closed formulary proposals Question. In an attempt to bring down drug costs, various states have been exploring whether to exclude certain drugs from its Medicaid program. for example, the state of Massachusetts' recently asked CMS for permission to create a closed formulary where the state Medicaid program would pick at least one drug per therapeutic class. CMS denied their waiver request citing violation of federal law, but this proposal does bring up important questions on how to contain drug prices in state Medicaid programs. If the principles of the Medicare Part D program--including the necessary patient protections--were applied to state Medicaid programs, do you think it lower drugs costs while ensuring access to patients? Answer. Medicaid patients currently have broad access to medicines with nominal co-pay amounts in exchange for steep mandatory rebates provided by manufacturers. While the question does not specify what ``principles of the Medicare Part D program'' or ``necessary patient protections'' are proposed to be applied to State Medicaid programs, depending on the specific details that might be proposed, exclusionary formularies could upset this broad patient access in Medicaid without achieving corresponding savings over the already-existing steep mandatory rebates. medicaid ``best price'' Question. In the Trump administration's Blueprint, they suggested that because drug manufactures have to give Medicaid the ``best price'' on drugs, there is no incentive to offer deeper discounts to other payers--both government and commercial--than what is already offered under the Medicaid Drug Rebate Program. Does the Medicaid ``best price'' requirement encourage manufacturers to increase initial prices? What, if any, changes would you suggest we make to the program? Answer. AbbVie has not found that best price requirements have created incentives in the system to increase initial prices. outcomes-based contracts Question. In almost all of your testimonies, you highlight your support of outcomes-based contracts and how we need to be shifting our system toward that approach. How will these contracts lower drug costs for patients in both the near term and long-term? How will they lower overall health-care costs for our Federal programs? What have the preliminary results looked like so far? Answer. Value-based arrangements can be an effective and market- based solution to managing overall health-care costs when driven by patient outcomes. Studies have found that 38 percent of payers with outcomes-based contracts experience improved patient outcomes and 33 percent experience plan health-care cost savings. Additionally, plans with outcomes-based contracts have been found to have a 28 percent lower patient co-payment. All of these factors work towards moving payment for prescription medicines away from volume-based approaches to value-based models in a manner that appropriately balances patient access with the appropriate use of medications to lower overall health- care costs. At AbbVie, we believe all our products provide value to patients and the larger health care system and are interested in the possibilities that could arise through value-based contracting. To further foster value-based arrangements, we support the reforms included in the Patient Affordability, Value and Efficiency (PAVE) Act, introduced by Senators Cassidy (R-LA) and Warner (D-VA). transparency/point of sale Question. In almost all of your testimonies, you express your support for the Trump Administration's proposal to allow manufacturers to provide PBMs up-front discounts that are passed onto patients at the point-of-sale. Do you feel like this proposal will make the transactions within the drug supply chain more transparent? If so, would this transparency bring down drug costs--overall and for specialty drugs? Answer. There has been significant discussion over the past several months about proposals to eliminate rebates from Medicare Part D, Medicaid, and the commercial market culminating in the administration's publication of a proposed rule to ``expressly exclud[e] from safe harbor protection under the Anti-Kickback Statute (AKS) rebates on prescription drugs paid by manufacturers to pharmacy benefit managers (PBMs), Part D plans, and Medicaid managed care organizations. The proposal would create a new safe harbor protecting discounts offered to patients at the pharmacy counter. Finally, the proposal would create new safe harbor protection for fixed fee services arrangements between manufacturers and PBMs.'' AbbVie is encouraged by the goals of the proposed rule to ensure manufacturer discounts are reflected in and reduce patient cost sharing under Part D. While we believe the rule is an important step in the right direction, we also believe more should be done to help reduce the out-of-pocket cost burden on Medicare Part D patients. As for what the elimination of rebates might mean to the overall health care system or pharmaceutical companies, it is premature to comment on these items until the Administration's rule is finalized, implementation timelines are solidified and there are specific details regarding how a new system without rebates will be structured and function. the relationship between wholesalers and manufacturers Question. When talking about the pharmaceutical supply chain, a lot of focus has been placed on the Pharmacy Benefit Manager. But there's another side of the equation that I'd like to ask about. How do wholesalers negotiate pricing with manufacturers? What impact does this have on drug costs? What incentives or disincentives do they have to contain price increases? Answer. Wholesalers provide efficiencies in the distribution of products for manufacturers, pharmacies and providers. They track supply needs and maintain inventory levels consistent with patient need. They also provide manufacturers with data and information related to both historical purchasing patterns and projected future need, allowing manufacturers to more accurately predict future supply needed in the market to determine production needs. Wholesalers are also a ``one-stop shop'' for sourcing medications and in some cases provide payer contracting efficiencies through their Pharmacy Services Administrative Organizations. This allows pharmacies to gain access to payer networks efficiently, without negotiating with individual payers. Manufacturers pay bona fide fees to wholesalers cover the costs of the services described above. ______ Questions Submitted by Hon. Ron Wyden proposed rebate rule Question. As has been done in many other settings, drug manufacturers said during the hearing that one reason list prices for drugs are high is that pharmaceutical benefit managers (PBMs) demand larger and larger rebates in order for the drug to receive favorable placement on a formulary. You and your colleagues who testified during the hearing stated if the Administration's proposal on changes to the anti-kickback safe harbor for pharmaceutical rebates took effect, your company would likely lower list price. Like many Oregonians, I am skeptical drug manufacturers would voluntarily lower their prices. Therefore, would you support legislation that would (1) make similar changes the administration has put forward related to Part D and Medicaid managed care, (2) change the rebate system in a similar way to the proposal for the commercial market, and (3) require drug makers to lower the list price of their drugs equal to the amount of rebates provided today? Answer. There has been significant discussion over the past several months about proposals to eliminate rebates from Medicare Part D, Medicaid, and the commercial market culminating in the administration's publication of a proposed rule to ``expressly exclud[e] from safe harbor protection under the Anti-Kickback Statute (AKS) rebates on prescription drugs paid by manufacturers to pharmacy benefit managers (PBMs), Part D plans, and Medicaid managed care organizations. The proposal would create a new safe harbor protecting discounts offered to patients at the pharmacy counter. Finally, the proposal would create new safe harbor protection for fixed fee services arrangements between manufacturers and PBMs.'' AbbVie is encouraged by the goals of the proposed rule to ensure manufacturer discounts are reflected in and reduce patient cost sharing under Part D. While we believe the rule is an important step in the right direction, we also believe more should be done to help reduce the out-of-pocket cost burden on Medicare Part D patients. As for what the elimination of rebates might mean to the overall health-care system or pharmaceutical companies, it is premature to comment on these items until the administration's rule is finalized, implementation timelines are solidified, and there are specific details regarding how a new system without rebates will be structured and function. medicaid drug rebate program Question. The Medicaid Drug Rebate Program (MDRP) requires manufacturers to provide a basic rebate and an additional inflationary rebate for both brand and generic drugs. The inflationary rebate is an increasingly substantial part of total rebates due in large part to large increases in drug prices that exceed inflation. Under current law, this inflationary rebate is capped at 100 percent of Average Manufacturer Price (AMP). This is the case even when manufacturers continue to raise their prices well above inflation. Please provide a list of all of your pharmaceutical products that have reached the Medicaid AMP rebate cap in any of the 20 quarters from January 1, 2014 through December 31, 2018. For each drug listed in response to question 1, please also provide a list of which quarters and years each drug hit the cap. Answer. ------------------------------------------------------------------------ PRODUCT NAME NDC 11 QTR/YEAR of AMP CAPs ------------------------------------------------------------------------ Androgel 1%, 2.5 G Unit 00051-8425-30 Q1 2015 Dose, 30'S ------------------------------------------------------------------------ Androgel 1%, 5.0 G Unit 00051-8450-30 Q1 2015 Dose, 30'S ------------------------------------------------------------------------ Androgel 1.62% 2.5Gm Unit 00051-8462-30 Q2 2017, Q1 2018-Q3 2018 Dose ------------------------------------------------------------------------ Androgel 1.62% 1.25Gm Unit 00051-8462-31 Q2 2017, Q1 2018-Q3 2018 Dose ------------------------------------------------------------------------ Androgel 1.62% Pump 00051-8462-33 Q2 2017, Q1 2018-Q3 2018 ------------------------------------------------------------------------ Biaxin, Filmtab Tablets, 00074-2586-60 Q3 2016-Q4 2016 500 Mg, 60'S ------------------------------------------------------------------------ Biaxin XL, Filmtab Tab, 00074-3165-11 Q1 2014-Q4 2015 500 Mg, 1010'S ------------------------------------------------------------------------ Biaxin XL 500Mg(114) 00074-3165-14 Q1 2014-Q4 2015 ------------------------------------------------------------------------ Biaxin XL, Filmtab Tabs, 00074-3165-41 Q1 2014-Q4 2015 500Mg, 414'S ------------------------------------------------------------------------ Biaxin XL, Filmtab 00074-3165-60 Q1 2014-Q4 2015 Tablets, 500 Mg, 60'S ------------------------------------------------------------------------ Biaxin OS, 250Mg/5Ml, 00074-3188-13 Q2 2014-Q3 2014, Q1 2016- 100ML Q2 2018 ------------------------------------------------------------------------ Biaxin OS 250Mg/5Ml, 50ML 00074-3188-50 Q2 2014-Q3 2014, Q1 2016- Q2 2018 ------------------------------------------------------------------------ Biaxin Filmtab Tablets, 00074-3368-60 Q1 2014, Q3 2014, Q1 2015- 250 Mg, 60'S Q3 2015 ------------------------------------------------------------------------ Cardizem LA , Tablets, 120 00074-3045-30 Q1 2014-Q3 2014 Mg, 30'S ------------------------------------------------------------------------ Cardizem LA , Tablets, 120 00074-3045-90 Q1 2014-Q3 2014 Mg, 90'S ------------------------------------------------------------------------ Cardizem LA , Tablets, 180 00074-3061-30 Q1 2014 Mg, 30'S ------------------------------------------------------------------------ Cardizem LA , Tablets, 180 00074-3061-90 Q1 2014 Mg, 90'S ------------------------------------------------------------------------ Cardizem LA , Tablets, 240 00074-3062-30 Q1 2014 Mg, 30'S ------------------------------------------------------------------------ Cardizem LA , Tablets, 240 00074-3062-90 Q1 2014 Mg, 90'S ------------------------------------------------------------------------ Cardizem LA , Tablets, 300 00074-3063-30 Q1 2014 Mg, 30'S ------------------------------------------------------------------------ Cardizem LA , Tablets, 300 00074-3063-90 Q1 2014 Mg, 90'S ------------------------------------------------------------------------ Cardizem LA , Tablets, 360 00074-3064-30 Q1 2014-Q2 2014 Mg, 30'S ------------------------------------------------------------------------ Cardizem LA , Tablets, 360 00074-3064-90 Q1 2014-Q2 2014 Mg, 90'S ------------------------------------------------------------------------ Cardizem LA , Tablets, 420 00074-3069-30 Q1 2014 Mg, 30'S ------------------------------------------------------------------------ Cardizem LA, Tablets, 420 00074-3069-90 Q1 2014 Mg, 90'S ------------------------------------------------------------------------ Depacon 500Mg (100Mg/1ML) 00074-1564-10 Q1 2016, Q4 2016-Q4 2017 105ML SDV ------------------------------------------------------------------------ Depakene 250Mg 100Cap 00074-5681-13 Q1 2014, Q3 2014-Q4 2018 ------------------------------------------------------------------------ Depakene OS 250Mg/5ML, 00074-5682-16 Q3 2014-Q4 2018 16Oz ------------------------------------------------------------------------ Depakote ER 250Mg 1010Tab 00074-3826-11 Q1 2015, Q4 2018 ------------------------------------------------------------------------ Depakote ER 250Mg 100Tab 00074-3826-13 Q1 2015, Q4 2018 ------------------------------------------------------------------------ Depakote, Sprinkle 00074-6114-11 Q1 2015-Q4 2018 Capsule, 125 Mg, 10-10 ------------------------------------------------------------------------ Depakote Sprinkle Capsule, 00074-6114-13 Q1 2015-Q4 2018 125Mg, 100 ------------------------------------------------------------------------ Depakote 125Mg 100Tab 00074-6212-13 Q1 2014, Q3 2014-Q4 2018 ------------------------------------------------------------------------ Depakote 250Mg 100Tab 00074-6214-13 Q1 2014, Q3 2014-Q4 2018 ------------------------------------------------------------------------ Depakote 250Mg 500Tab 00074-6214-53 Q1 2014, Q3 2014-Q4 2018 ------------------------------------------------------------------------ Depakote 500Mg 100Tab 00074-6215-13 Q1 2014, Q3 2014-Q4 2018 ------------------------------------------------------------------------ Depakote 500Mg 500Tab 00074-6215-53 Q1 2014, Q3 2014-Q4 2018 ------------------------------------------------------------------------ Depakote ER 500Mg 10X10Tab 00074-7126-11 Q4 2014-Q1 2015, Q1 2017- Q3 2017, Q4 2018 ------------------------------------------------------------------------ Depakote ER 500Mg 100Tab 00074-7126-13 Q4 2014-Q1 2015, Q1 2017- Q3 2017, Q4 2018 ------------------------------------------------------------------------ Depakote ER 500Mg 500Tab 00074-7126-53 Q4 2014-Q1 2015, Q1 2017- Q3 2017, Q4 2018 ------------------------------------------------------------------------ Humira 40Mg/0.8ML (2 00074-3799-02 Q2 2016-Q4 2018 Syringes) ------------------------------------------------------------------------ Humira Ped Crohns Starter 00074-3799-03 Q2 2016-Q4 2018 Pack, 40Mg ------------------------------------------------------------------------ Humira Ped Crohns Starter 00074-3799-06 Q2 2016-Q4 2018 Pack, 40Mg ------------------------------------------------------------------------ Humira 40Mg/0.8 ML (2 00074-4339-02 Q2 2016-Q4 2018 Pens) ------------------------------------------------------------------------ Humira, Crohn's, 40Mg/0.8 00074-4339-06 Q2 2016-Q4 2018 ML (6 Pens) ------------------------------------------------------------------------ Humira, Psoriasis, 40Mg/ 00074-4339-07 Q2 2016-Q4 2018 0.8ML (4 Pens) ------------------------------------------------------------------------ Humira, Single Dose 00074-6347-02 Q2 2016-Q4 2018 Syringe, 10 Mg/0.2ML ------------------------------------------------------------------------ Humira 20Mg/0.4ML (2 00074-9374-02 Q2 2016-Q4 2018 Syringes) ------------------------------------------------------------------------ K-Tab, Filmtabs, 8Meq, 00074-3058-41 Q3 2018 600Mg, 100Ct ------------------------------------------------------------------------ K-Tab, Filmtabs, 8Meq, 00074-3058-46 Q3 2018 600Mg, 1000Ct ------------------------------------------------------------------------ Marinol 2.5 Mg Capsules, 00051-0021-21 Q2 2016 60'S ------------------------------------------------------------------------ Marinol 5 Mg Capsules, 00051-0022-21 Q3 2018 60'S ------------------------------------------------------------------------ Marinol 10 Mg Capsules, 00051-0023-21 Q2 2014, Q3 2017 60'S ------------------------------------------------------------------------ Mavik, Tablets, 1 Mg, 00074-2278-13 Q4 2014, Q2 2015 100'S ------------------------------------------------------------------------ Niaspan, Tablets, 500 Mg, 00074-3074-90 Q1 2014, Q2 2015, Q1 2016- 90'S Q3 2016, Q1 2017-Q4 2018 ------------------------------------------------------------------------ Niaspan, Tablets, 750 Mg, 00074-3079-90 Q1 2014, Q4 2014, Q2 2015- 90'S Q2 2016, Q4 2016-Q4 2018 ------------------------------------------------------------------------ Niaspan, Tablets, 1000 Mg, 00074-3080-90 Q1 2014, Q1 2015-Q2 2015, 90'S Q1 2016-Q3 2016, Q1 2017- Q4 2018 ------------------------------------------------------------------------ Niaspan, Tablets, 500Mg, 00074-3265-90 Q4 2017-Q4 2018 90'S ------------------------------------------------------------------------ Niaspan, Tablets, 750Mg 00074-3274-90 Q1 2018-Q4 2018 90'S ------------------------------------------------------------------------ Niaspan, Tablets, 1000Mg 00074-3275-90 Q4 2017-Q4 2018 90'S ------------------------------------------------------------------------ Prometrium 100 Mg 00032-1708-01 Q2 2016-Q4 2018 Capsules, 100'S ------------------------------------------------------------------------ Prometrium 200 Mg 00032-1711-01 Q2 2016-Q4 2018 Capsules, 100'S ------------------------------------------------------------------------ Simcor 500Mg/20Mg, 90Tab 00074-3312-90 Q3 2014 ------------------------------------------------------------------------ Simcor 1000Mg/20Mg, 90Tab 00074-3455-90 Q1 2014, Q3 2014 ------------------------------------------------------------------------ Tarka ER 2Mg/180Mg, 100Tab 00074-3287-13 Q2 2015-Q4 2015, Q2 2016- Q4 2016, Q2 2017-Q4 2017, Q2 2018-Q4 2018 ------------------------------------------------------------------------ Tarka 1Mg/240Mg, 100Tab 00074-3288-13 Q2 2015-Q4 2015, Q2 2016- Q4 2018 ------------------------------------------------------------------------ Tarka ER 2Mg/240Mg, 100Tab 00074-3289-13 Q1 2014, Q2 2015-Q4 2015, Q2 2016-Q4 2016, Q2 2017- Q4 2017, Q2 2018-Q4 2018 ------------------------------------------------------------------------ Tarka ER 4Mg/240Mg, 100Tab 00074-3290-13 Q1 2014, Q1 2015-Q3 2015, Q1 2016-Q2 2016, Q4 2016- Q2 2017, Q4 2017-Q3 2018 ------------------------------------------------------------------------ Tricor, Tablets, 145Mg, 00074-3189-90 Q3 2018 90Ct Btl ------------------------------------------------------------------------ Tricor, Tablets, 48 Mg, 00074-6122-90 Q4 2014-Q1 2015 90'S ------------------------------------------------------------------------ Tricor, Tablets, 145 Mg, 00074-6123-90 Q3 2018 90'S ------------------------------------------------------------------------ Trilipix, Delayed Release 00074-3161-90 Q2 2017-Q4 2017, Q2 2018- Cap, 45Mg 90Ct Q4 2018 ------------------------------------------------------------------------ Trilipix, Delayed Release 00074-9189-90 Q3 2018-Q4 2018 Cap, 135Mg 90'S ------------------------------------------------------------------------ Trilipix, Delayed Release 00074-9642-90 Q3 2014-Q4 2014, Q2 2015- Cap, 45Mg 90'S Q3 2015, Q1 2016, Q3 2016-Q4 2016, Q2 2017-Q4 2017, Q2 2018-Q4 2018 ------------------------------------------------------------------------ Zemplar, Capsules, 2 Mcg, 00074-4314-30 Q3 2014-Q1 2015, Q3 2015- 30'S Q4 2015, Q2 2016-Q4 2016, Q2 2017, Q4 2017- Q4 2018 ------------------------------------------------------------------------ Zemplar, Capsules, 4 Mcg, 00074-4315-30 Q2 2014-Q4 2015 30'S ------------------------------------------------------------------------ Zemplar, Capsules, 1 Mcg, 00074-4317-30 Q4 2014, Q2 2015, Q4 30'S 2015, Q2 2016, Q1 2018- Q4 2018 ------------------------------------------------------------------------ medicaid drug rebate program compliance Question. I am concerned about recent reports and legal settlements surrounding drug manufacturers' failure to comply fully with the requirements of the MDRP. for example, an analysis by the U.S. Department of Health and Human Services office of Inspector General found that between 2012 and 2016 taxpayers may have overpaid by as much as $1.3 billion for 10 potentially misclassified drugs. That is why I introduced the Right Rebate Act with Chairman Grassley to prevent drug manufacturers from manipulating Medicaid to increase their profits. However, I continued to be concerned about oversight and manufacturer compliance with the requirements of the Medicaid Drug Rebate Program. Accordingly, please describe the following: Your company's current compliance plan and procedures used to ensure compliance with the requirements of the Medicaid Drug Rebate Program including internal audits or other checks you use to identify compliance vulnerabilities. Answer. AbbVie has established and maintains a comprehensive compliance plan and procedures to ensure MDRP compliance, the core components of which include policies and procedures relating to MDRP issues, routine internal and external monitoring and auditing, and a dedicated governance team to monitor and address any potential MDRP issues. Question. Any past or ongoing issues of non-compliance. Answer. We are not aware of past or ongoing issues of non- compliance with MDRP legal requirements. Question. Any corrective actions taken to address identified problems or issues of noncompliance with the MDRP and how such steps were communicated to the Centers for Medicare and Medicaid Services. Answer. We are not aware of past or ongoing issues of non- compliance with MDRP legal requirements. Question. Any steps taken to improve compliance and ensure that all Medicaid drug rebates owed to the Federal Government and the States are paid in full. Answer. AbbVie conducts periodic reviews of its compliance plan and updates its policies, procedures, and monitoring plans as needed to ensure the company's continued implementation of MDRP legal requirements. bonus payments tied to specific drugs Question. I am concerned by the potential for employee financial incentives to encourage high launch prices and price increases for prescription drugs. Is your salary, bonus, or other compensation tied to sales or revenue targets of a single product your company sells? Has it ever been? If yes, please state the product or products to which your salary, bonus or other compensation was tied. Is your salary, bonus, or other compensation tied to either revenue or net income of the company as a whole? Has it ever been? If yes, please explain what assumptions about price increases are used when the compensation committee sets revenue or net income goals. Does the compensation committee provide any guidance to executives in regards to the amount of revenue that the company will generate from price increases versus volume growth? Answer. To determine Mr. Gonzalez's 2018 annual incentive compensation (sometimes referred to as a bonus), net revenues, income before taxes, and Humira sales were three of several quantitative financial metrics that were considered in addition to qualitative factors. At most, a single quantitative financial metric had the potential to impact up to 3 percent of Mr. Gonzalez's total compensation, subject to additional qualitative and relative analyses. No other compensation element, beyond the annual incentive compensation, includes Humira sales, revenue, or net income as a performance metric. While some specific details have differed somewhat, the foregoing has generally been true in prior years as well. ______ Questions Submitted by Hon. Robert Menendez Question. When new products enter the market, do drug companies set high initial rebates and then provide deep rebates in order to gain access to insurance plan's formularies? Answer. Over the last 2 years, AbbVie has brought Mavyret and Orilissa to patients. Mavyret is for the treatment of adults with chronic hepatitis C virus (HCV) infection across all major genotypes, and Orilissa is the first and only oral gonadotropin-releasing hormone antagonist specifically developed for women with moderate to severe endometriosis pain. Mavyret was introduced with a list price below competitive alternatives and Orilissa was introduced at a list price below the current standard of care. Rebates are a form of price competition that results from the aggressive negotiations that occur between health plans (and their representative PBMs) and pharmaceutical companies to provide patients with access to medicines and treatments that can best help patients manage their medical conditions. Plans/PBMs create formularies to list brand and generic medicines. Question. If CMS finalizes the rebate rule, do you anticipate future products entering the market with significantly lower initial list prices? Answer. There has been significant discussion over the past several months about proposals to eliminate rebates from Medicare Part D, Medicaid, and the commercial market culminating in the administration's publication of a proposed rule to ``expressly exclud[e] from safe harbor protection under the Anti-Kickback Statute (AKS) rebates on prescription drugs paid by manufacturers to pharmacy benefit managers (PBMs), Part D plans, and Medicaid managed care organizations. The proposal would create a new safe harbor protecting discounts offered to patients at the pharmacy counter. Finally, the proposal would create new safe harbor protection for fixed fee services arrangements between manufacturers and PBMs.'' AbbVie is encouraged by the goals of the proposed rule to ensure manufacturer discounts are reflected in and reduce patient cost sharing under Part D. While we believe the rule is an important step in the right direction, we also believe more should be done to help reduce the out-of-pocket cost burden on Medicare Part D patients. As for what the elimination of rebates might mean to the overall health care system or pharmaceutical companies, it is premature to comment on these items until the Administration's rule is finalized, implementation timelines are solidified and there are specific details regarding how a new system without rebates will be structured and function. ______ Questions Submitted by Hon. Thomas R. Carper Question. What are your recommendations for lowering prices for the 40 percent of drugs that do not offer rebates in Medicare Part D? Answer. A majority of the discussion about the cost of prescription drugs has been focused on list prices. We agree that price should be part of the discussion, however we also know that solutions targeting list price alone are not enough. Our experience in launching a low list price HCV medicine made it clear to AbbVie and patients that list price reductions will not always address patient affordability and access. Providing discounts to the patient at the point of sale is an effective way of ensuring that patients can see lower out-of-pocket costs. However, this is just the start. AbbVie believes that more must be done. The Medicare Part D benefit design contributes to making innovative therapies cost-prohibitive for Medicare patients because patients are charged out-of-pocket costs based on a medicine's list price, which does not reflect the rebates that Medicare receives. AbbVie believes it is important to alleviate the burdens that patients face due to Medicare Part D out-of-pocket costs. AbbVie supports solutions like a patient out-of-pocket cap in Part D and smoothing patient out-of-pocket payments over a full year, so patients have some predictability with respect to their out-of-pocket costs. In addition, AbbVie is prepared to step up and discuss how companies like ours can shoulder more of the burden of a patient's out- of-pocket expenses. As policymakers consider the impact of addressing out-of-pocket costs in Medicare Part D, questions may arise around whether it will lead to unnecessary utilization and wasteful spending. for specialty medicines, increased utilization should not be misunderstood as unnecessary or wasteful. Part D plans have tools, like step therapy requirements for patients to first try lower cost alternatives before a specialty medicine would be covered and prior authorization requirements before a specialty medicine would be covered, to manage the utilization of the majority of higher cost specialty medicines. These tools ensure patients try a less costly medication first and have met the clinical criteria for taking the specialty drug prescribed and serve the function that an out-of-pocket cost obligation on patients might serve to prevent unnecessary use. Question. In the health insurance plans that you offer your employees, do you ask your insurers to pass through the full manufacturer rebates to the beneficiaries? Answer. AbbVie's benefit plans are structured to ensure employees share in the cost of their prescription drugs but are also able to access and afford their medicines, with the goal of maximizing prescription drug adherence. Currently our maximum co-pays and out-of-pocket maximums ensure patient access and allow us to utilize rebates to reduce premiums. Our benefit includes a deductible and 25-percent co-pay for prescription medicines that is capped at $125 for a 30-day supply. For mail order or specialty pharmacy, there is a 20-percent co-pay that is capped at $250 for a 90-day supply. Additionally, our benefit plans include an annual out-of-pocket maximum. Our prescription drug adherence levels are high year over year across many disease states. To increase transparency, members receive a receipt at retail or via mail/specialty pharmacies that reflects their share of the discounted price of the drug. AbbVie has considered the impact of passing through rebates to employees and have found a minimal impact on employee out-of-pocket expenses for all medicines, including specialty. We have found that it would only reduce employee spending if the rebate reduced the co- payment obligation below $125 for drugs filled at retail or $250 for mail order or specialty drugs. Employees who would benefit the most in this scenario would be those in high deductible health plans before they meet their deductible, however it could slow the time in which they would reach their deductible. While we have found that providing rebates at point of sale is most beneficial to enrollees whose benefit design does not include a maximum co-pay and therefore may not be beneficial to AbbVie employees, we are continuing to assess the impact in a manner that ensures we can maintain the current employee costsharing levels in our benefit design that drive adherence. Question. The systems for pricing and distributing drugs are opaque and difficult to understand. What are your recommendations for increasing transparency in how your companies set the list prices for drugs, and for improving transparency in the supply chain for prescription drugs? Would you support federal standards for transparency in setting the list prices for drugs? Answer. AbbVie supports transparency that is accurate, timely, comprehensive and meaningful to patients as they make better-informed decisions about their health care. This includes broad transparency across the entire health-care system and consistent requirements, including for all entities in the drug supply chain, rather than a narrow focus on one individual sector. It is also important that any new transparency requirements are prospective and balanced with appropriate protections for confidential, proprietary information so as not to undermine competition in the marketplace. As Congress considers approaches to address transparency at the Federal level, AbbVie welcomes further discussion on this important topic. Question. In nearly every sector of the health-care industry, Medicare, Medicaid, employers, and insurers are moving away from fee- for-service payments to reimbursements based on value and performance. Prescription drugs and medical devices were the glaring exceptions to this trend until recently. How many of your drugs are included in valuebased contracts and how many patients are benefiting from them? How do these valuebased contracts work to lower drug prices for both patients and taxpayers? Answer. Value-based arrangements can be an effective and market- based solution to managing overall health-care costs when driven by patient outcomes. Studies have found that 38 percent of payers with outcomes-based contracts experience improved patient outcomes and 33 percent experience plan health-care cost savings. Additionally, plans with outcomes-based contracts have been found to have a 28 percent lower patient co-payment. All of these factors work towards moving payment for prescription medicines away from volume-based approaches to value-based models in a manner that appropriately balances patient access with the appropriate use of medications to lower overall health- care costs. At AbbVie, we believe all our products provide value to patients and the larger health care system and are interested in the possibilities that could arise through value-based contracting. To further foster value-based arrangements, we support the reforms included in the Patient Affordability, Value and Efficiency (PAVE) Act, introduced by Senators Cassidy (R-LA) and Warner (D-VA). Question. Last year, Senator Portman and I did an investigation on the pricing of an opioid overdose reversal drug called EVZIO, manufactured by Kaleo. Kaleo increased the price of EVZIO from $575 in 2014 to $4,100 in 2017. We found that the best price Medicare was able to get for EVZIO, about $4,000, was much higher than the price other federal programs and private insurers were able to get. It seemed that Kaleo was able to get this higher price of $4,000 from Medicare by helping doctors fill out paperwork showing that the drug was medically necessary, even though there are cheaper alternatives on the market. As a result of the investigation, Kaleo announced it will bring a generic version of the drug to market at only $168 per pack. Are any of your companies providing medical necessity paperwork to doctors in order to get your drugs covered by Medicare? Answer. Unlike the scenarios raised in this question, AbbVie does not have a practice of completing medical necessity sections on any reimbursement forms, purporting to make medical necessity determinations that should be made by physicians, or submitting medical necessity forms to payors on behalf of patients or physicians. Question. In 2017, the Rand Corporation estimated that biosimilar drugs, which are competitors to complex, biologic drugs, could save the United States more than $50 billion over the next decade. Some of you have also argued that increasing the use of biosimilar drugs would help lower drugs costs for consumers and taxpayers. What is delaying the uptake of biosimilar drugs in the United States? What policies do you recommend to increase the development of biosimilar drugs? Answer. AbbVie believes that FDA's current, patient-centered and science-based approach to the development of standards governing the approval of biosimilars--including interchangeable biosimilars--helps to build a sustainable biosimilar market as patients and health care providers become more exposed to, and comfortable with, these products. The agency's approach best ensures the approval of quality, safe, and effective biosimilar products--products that will instill confidence among patients and prescribers. A robust and competitive biologic marketplace cannot survive without this stakeholder confidence and support. Any policies regarding the biologics market must take into consideration the fundamental differences between small molecule generics and biosimilars. Consequently, competition between biosimilars and their reference products will necessarily more closely resemble brand-to-brand competition. A key principle for encouraging appropriate market competition for biological products, then, is ensuring a level playing field for all biologic products. Artificially favoring either biosimilars or innovator biologics in coverage or reimbursement creates market inefficiencies by reducing incentives to compete on price. Moreover, policies designed to artificially drive usage of either the biosimilar or the reference biologic risk confusing stakeholders regarding the clear regulatory distinctions between biosimilars and small-molecule generics. Robust competition should therefore be driven by an increasing number of innovator and biosimilar products competing to treat disease at the lowest possible cost. ______ Questions Submitted by Hon. Benjamin L. Cardin Question. The United States is one of the only countries in the world to allow prescription drug manufacturers to advertise directly to consumers through magazines, billboards, radio, and television commercials. While I will not argue that it is beneficial to educate consumers about an unfamiliar disease and encourage them to seek medical help, most commercials from all of your companies recommend asking about a specific brand name drug, not a medical condition. Furthermore, even if your advertisements follow all FDA rules and list medication side effects, they also almost always list these while a smiling, apparently healthy person is walking on a beach. Researchers say that this type of imagery, combined with viewing hours of drug commercials each month, leads consumers to underestimate the risks associated with medications. for the past decade, studies have shown that aggressive direct-toconsumer advertising is associated with rising drug prices and an increase in inappropriate drug prescriptions. Since researchers have concluded that consumers are misunderstanding the benefits and risks described in your ads, what further policies could help you and your colleagues ensure that you are educating patients in a clear manner? Answer. We believe it is unlikely that DTC advertising would lead to an ``increase in inappropriate prescriptions'' for AbbVie's largely specialty-product portfolio. Both commercial insurance and Part D plans have tools, like step therapy requirements for patients to first try lower cost alternatives before a specialty medicine would be covered and prior authorization requirements before a specialty medicine would be covered to manage the utilization of the majority of higher cost specialty medicines. These tools ensure patients try a less costly medication first and have met the clinical criteria for taking the specialty drug prescribed. Further, we believe that consumers understand the benefits and risks described in AbbVie's advertisements. AbbVie goes beyond the FDA regulations to ensure its advertising it accurate, truthful, not misleading, and reflects an appropriate balance between the risks and benefits of the drugs. This includes complying with PhRMA's voluntary principles on direct to consumer advertising.\2\ Some of the key principles addressing the issues of educating patients in a clear manner include: --------------------------------------------------------------------------- \2\ See http://phrmadocs.phrma.org/files/dmfile/PhRMA--Guiding-- Principles_2018.pdf. Companies that choose to feature actors in the roles of health-care professionals in a DTC television or print advertisement that identifies a particular product should acknowledge in the advertisement that actors are being used. Likewise, if actual health-care professionals appear in such advertisements, the advertisement should include an acknowledgment if the health-care professional is compensated --------------------------------------------------------------------------- for the appearance. DTC television advertising that identifies a product by name should clearly state the health conditions for which the medicine is approved and the major risks associated with the medicine being advertised. DTC television and print advertising should be designed to achieve a balanced presentation of both the benefits and the risks associated with the advertised prescription medicine. Specifically, risks and safety information, including the substance of relevant boxed warnings, should be presented with reasonably comparable prominence to the benefit information, in a clear, conspicuous and neutral manner, and without distraction from the content. In addition, DTC television advertisements should support responsible patient education by directing patients to health care professionals as well as to print advertisements and/or websites where additional benefit and risk information is available. All DTC advertising should respect the seriousness of the health conditions and the medicine being advertised. AbbVie believes these are important principles that all pharmaceutical advertisements should follow. Our approach of listening to, and learning from, consumers, caregivers, physicians and other health-care professionals continues to confirm our belief that accurate, balanced and timely information about our prescription medicines and the conditions they treat is an essential component of our commitment to putting patient health first. pharmaceutical companies continue to raise prices Question. As you are well aware, high prescription drug prices are the number one concern for Americans and their families. According to the Organization for Economic Cooperation and Development, the average American spends around $1,208 annually on prescription drugs. There have been several instances where brand name or even generic drugs that have been on the market for years continue to increase in price. One of the most well known examples is Mylan's increase of the price of EpiPen from less than $100 in 2007 to more than $600 in 2016. Another example, is the everincreasing price of insulin. Sanofi increased the price of a vial of Lantus from $88.20 in 2007 to $307.20 in 2017. And those are just a small sample of price increases. Why don't we see price decreases for drugs that have been on the market for years without new formulations or added benefit? Answer. Price often does decrease for drugs that have been on the market for years. The U.S. has a robust and well-functioning system with fast entry of generic medicines following the expiration of patent and market exclusivities for brand medications. When generics medicines enter the market price reductions can be dramatic. In fact, GAO has found that prices are typically reduced by 20 percent for each new generic entrant to the market. From 2005 to 2013 prices of medicines commonly used to prevent cardiovascular disease dropped 92 percent. The daily cost of the top 10 therapeutic classes of medicines most commonly used by Medicare Part D enrollees dropped from $1.50 to $0.77 from 2006 to 2013. In addition to dramatic decreases in price, generic uptake is swift in the U.S. When a generic version of a medicine becomes available for the first time, it captures an average of three-quarters of the market within 3 months. Some generics captures as much as 90 percent in that same time period. Utilization is also the highest in the U.S. when compared to uptake in other markets, such as the UK, France, Japan, Germany, and Australia. According to the 2018 Medicare Trustees Report, the generic utilization rate for Part D beneficiaries has steadily increased each year, from 75 percent in 2010 to 88 percent in 2017. Competition is also robust among branded products. From 2005 to 2011, the time only one medicine was available in its class declined from a median of 10 years in the 1970s to close to 2 years from 2005- 2011. Half of second medicines were approved within 2.3 years and one quarter were approved within just 4 months. These competitive forces lead to manufacturers offering discounts. An analysis by IQVIA found that net prices for brands continued to increase more slowly than invoice prices from 2013 to 2016, with average price increases for brands at 9.2 percent (down from 12 percent in 2015) and net price growth increases at 3.5 percent. For the same year, the analysis found that rebates, discounts, and other price concessions offset price growth for brand medicines by 62 percent. pay for delay Question. Pay for delay is a tactic that more and more branded drug manufacturers have been using to stifle competition from lower-cost generic manufacturers. This allows you to sidestep competition by offering patent settlements that pay generic companies not to bring lower-cost alternatives to market. These ``pay-for-delay'' patent settlements benefit both brand-name pharmaceutical companies by helping them avoid costly patent litigation and general manufacturers by rewarding them a hefty sum to delay entering the market with a cheaper drug alternative. However, these deals do not benefit consumers. According to an FTC study, these anticompetitive deals cost consumers and taxpayers $3.5 billion in higher drug costs every year. Does your company partake in pay-for-delay settlements? Why would a pharmaceutical company enter into a pay-for delay agreement? Do you think these agreements stifle competition and prevent generic alternatives to your branded medications? Answer. ``Pay-for-delay'' is not a self-defining phrase. With respect to the term ``pay,'' patent litigation settlements, like all litigation settlements, involve compromise in which both sides believe they are getting value from the resolution. There is no definition explaining the circumstances under which that value would implicate the term ``pay'' in ``pay-fordelay'' for purposes of these questions. And with respect to ``delay'' virtually all patent settlements provide for the generic competitor to enter the market before the expiration of the patent at issue. So if the alternative resolution of a patent lawsuit would be the innovator company continuing to enforce its patent until expiration, then such a settlement, no matter what value is exchanged, would actually accelerate competition, not delay it. drug rebate rule Question. In January, the Department of Health and Human Services' (HHS) office of Inspector General (OIG) promulgated a new regulation to remove regulatory safe harbor protections under the Anti-Kickback Statute (AKS) for rebates on prescription drugs rebates paid by manufactures to PBMs under Medicare Part D and for Medicaid managed care organizations (MCOs). The OIG proposal attempts to ban most rebates by eliminating their regulatory protections. The rule is predicted to increase net drug costs in its early years. The CMS actuaries estimate it would cost $196 billion over 10 years. Despite this high price tag, the beneficiary benefits are limited. The proposed rule notes that under the CMS Actuary's analysis, the majority of beneficiaries would see an increase in their total out- of-pocket payments and premium costs; reductions in total cost sharing will exceed total premium increases. I wanted to ask a question about the administration's rebate rule, which I understand that many of the drug manufacturers, and your main trade association, strongly support. According to an analysis of the rule by the Office of Actuaries at CMS, drug manufacturers are likely to initially retain 15 percent of the current rebates as higher net drug prices. Given that estimate, can you provide the committee with any assurances that prices will not increase under this proposed rule? Answer. There has been significant discussion over the past several months about proposals to eliminate rebates from Medicare Part D, Medicaid, and the commercial market culminating in the administration's publication of a proposed rule to ``expressly exclude[e] from safe harbor protection under the Anti-Kickback Statute (AKS) rebates on prescription drugs paid by manufacturers to pharmacy benefit managers (PBMs), Part D plans, and Medicaid managed care organizations. The proposal would create a new safe harbor protecting discounts offered to patients at the pharmacy counter. Finally, the proposal would create new safe harbor protection for fixed fee services arrangements between manufacturers and PBMs.'' AbbVie is encouraged by the goals of the proposed rule to ensure manufacturer discounts are reflected in and reduce patient cost sharing under Part D. While we believe the rule is an important step in the right direction, we also believe more should be done to help reduce the out-of-pocket cost burden on Medicare Part D patients. As for what the elimination of rebates might mean to the overall health care system or pharmaceutical companies, it is premature to comment on these items until the Administration's rule is finalized, implementation timelines are solidified and there are specific details regarding how a new system without rebates will be structured and function. ______ Questions Submitted by Hon. Sherrod Brown Question. According to an article recently published in the Journal of the American Medical Association, medical marketers spent nearly $30 billion dollars in 2016, up from $17 billion in 1997. Direct-to- Consumer (DTC) advertising had the biggest percentage increase: from $2.1 billion, or 11.9 percent of all medical marketing, in 1997 to $9.6 billion, or 32 percent of total spending, in 2016. Can each of you please provide what your ratio of spending on sales and marketing to research and development is today? Answer. AbbVie spends more on research and development than on global sales, marketing, and promotion costs. The global sales, marketing, and promotion spend in 2018 across all AbbVie products was $4.24 billion. This is less than the $5.26 billion AbbVie spent on research and development in 2018. And AbbVie's research and development spend does not include acquired inprocess research and development ($424 million in 2018) or money invested externally for technology, pharmaceutical compounds, or acquisitions. for example, AbbVie acquired Pharmacyclics for $20.8 billion in 2015 and Stemcentrx for $6.4 billion in 2016. The acquisition of both companies enhanced AbbVie's pipeline, research and development, and clinical programs. price-gouging Answer. Sanofi, as I understand it, has made a pledge to the public to limit its price increases to the national health expenditures growth projection. Would your company commit to a cap on annual price increases as part of your PhRMA membership criteria? Answer. With respect to the question's proposed collective agreement by PhRMA members to cap annual price increases, we note that in 1993, PhRMA (then known as PMA, the Pharmaceutical Manufacturers Association) sought review of such a proposal from the Antitrust Division of the Department of Justice. The Department of Justice opined that the proposed agreement for PhRMA members to collectively agree to limit their price increases would be per se unlawful under federal antitrust laws, even though the proposal was made ``in response to concerns about controlling health care costs.'' (Oct. 1, 1993 letter from Anne K. Bingaman, Assistant U.S. Attorney General, available at https://www.justice.gov/atr/response-pharmaceutical-manufacturers- associationsrequest-business-review-letter (``The PMA proposal is an arrangement among competitors that limits individual pricing decisions on its face. . . . An agreement among independent competitors that interferes with free and open price competition by restraining individual pricing decisions is a per se violation of the Sherman Act.'').) The Department of Justice said it ``intend[ed] to bring suit to challenge the program if PMA and its members go forward with its proposal.'' AbbVie could not support a proposal that the Department of Justice is on record as saying is unlawful and against which it would file suit to block. As for individual action, the same Department of Justice opinion discussed above noted that, while collective agreements among competitors raised antitrust violations, an individual company's decision to limit its own price increases would not be problematic. AbbVie in January 2017 became one of the first pharmaceutical companies to commit to limiting increases of its list prices. AbbVie committed to not more than one, single-digit price increase annually. AbbVie has abided by that commitment. Question. What policies would you propose to help ensure lower launch prices for new drugs? Answer. A majority of the discussion about the cost of prescription drugs has been focused on list prices. We agree that price should be part of the discussion, however we also know that solutions targeting list price alone are not enough. Our experience in launching a low list price HCV medicine made it clear to AbbVie and patients that list price reductions will not always address patient affordability and access. Providing discounts to the patient at the point of sale is an effective way of ensuring that patients can see lower out-of-pocket costs. However, this is just the start. AbbVie believes that more must be done. The Medicare Part D benefit design contributes to making innovative therapies cost-prohibitive for Medicare patients because patients are charged out-of-pocket costs based on a medicine's list price, which does not reflect the rebates that Medicare receives. AbbVie believes it is important to alleviate the burdens that patients face due to Medicare Part D out-of-pocket costs. AbbVie supports solutions like a patient outof-pocket cap in Part D and smoothing patient out-of-pocket payments over a full year, so patients have some predictability with respect to their out-of-pocket costs. In addition, AbbVie is prepared to step up and discuss how companies like ours can shoulder more of the burden of a patient's out- of-pocket expenses. As policymakers consider the impact of addressing out-of-pocket costs in Medicare Part D, questions may arise around whether it will lead to unnecessary utilization and wasteful spending. for specialty medicines, increased utilization should not be misunderstood as unnecessary or wasteful. Part D plans have tools, like step therapy requirements for patients to first try lower cost alternatives before a specialty medicine would be covered and prior authorization requirements before a specialty medicine would be covered, to manage the utilization of the majority of higher cost specialty medicines. These tools ensure patients try a less costly medication first and have met the clinical criteria for taking the specialty drug prescribed and serve the function that an out-of-pocket cost obligation on patients might serve to prevent unnecessary use. transparency Question. In many of your testimonies, you mentioned that the current system of pharmacy benefit manager (PBM) back-end rebates rarely results in a scenario where the PBM passes on savings to consumers at the point of sale (POS). The administration recently proposed a rule to eliminate the anti-kickback statute safe harbor protections for these drug rebates. Do you agree that greater transparency should be required to understand how manufacturers and PBMs are negotiating prices and rebates to ensure that savings are passed down to beneficiaries? Answer. AbbVie supports price transparency across all stakeholders that is accurate, timely, comprehensive, and meaningful to patients as they make better- informed decisions about their health care. This includes broad transparency across the entire health-care system and consistent requirements, including for all entities in the drug supply chain, rather than a narrow focus on one individual sector. It is also important that any new transparency requirements are prospective and balanced with appropriate protections for confidential, proprietary information so as not to undermine competition in the marketplace. pbms Question. An Axios article from March 7, 2019 highlights the fact that, while ``pharmaceutical companies put a lot of the blame for high drug prices on pharmacy benefit managers,'' many large pharmaceutical companies ``rely on PBMs to manage their own health-care benefits.'' In your role as an employer, does your company contract with a pharmaceutical benefit manager (PBM) to administer the prescription drug benefits for your employees and negotiate lower drug costs on your behalf? For those of you who do use a PBM to help manage the prescription drug benefit for your employees, how do you utilize the rebates your PBM negotiates to lower health-care costs or drug costs for your employee plans and what does your company do with that savings? Specifically, do the savings go toward lowing premiums? For those of you who do use a PBM to help manage the prescription drug benefit for your employees, does your PBM offer point-of-sale rebates to your employees? Answer. AbbVie does use a PBM to manage pharmacy benefits for its employees in the U.S. AbbVie's benefit plans are structured to ensure employees share in the cost of their prescription drugs but are also able to access and afford their medicines, with the goal of maximizing prescription drug adherence. Currently our maximum co-pays and out-of-pocket maximums ensure patient access and allows us to utilize rebates to reduce premiums. Our benefit includes a deductible and 25-percent co-pay for prescription medicines that is capped per prescription at $125 for a 30-day supply. For mail order or specialty pharmacy, there is a 20-percent co-pay that is capped per prescription at $250 for a 90-day supply. Additionally, our benefit plans include an annual out-of-pocket maximum. Our prescription drug adherence levels are high year over year across many disease states. To increase transparency, members receive a receipt at retail or via mail/specialty pharmacies that reflects their share of the discounted price of the drug. AbbVie has considered the impact of passing through rebates to employees and have found a minimal impact on employee out-of-pocket expenses for all medicines, including specialty. We have found that it would only reduce employee spending if the rebate reduced the co- payment obligation below $125 for drugs filled at retail or $250 for mail order or specialty drugs. Employees who would benefit the most in this scenario would be those in high deductible health plans before they meet their deductible, however it could slow the time in which they would reach their deductible. While we have found that providing rebates at point of sale is most beneficial to enrollees whose benefit design does not include a maximum co-pay and therefore may not be beneficial to AbbVie employees, we are continuing to assess the impact in a manner that ensures we can maintain the current employee cost-sharing levels in our benefit design that drive adherence. ______ Questions Submitted by Hon. Sheldon Whitehouse Question. Please describe any policy changes you support that would result in your company lowering the list prices of its drugs. Answer. A majority of the discussion about the cost of prescription drugs has been focused on list prices. We agree that price should be part of the discussion, however we also know that solutions targeting list price alone are not enough. Our experience in launching a low list price HCV medicine made it clear to AbbVie and patients that list price reductions will not always address patient affordability and access. Providing discounts to the patient at the point of sale is an effective way of ensuring that patients can see lower out-of-pocket costs. However, this is just the start. AbbVie believes that more must be done. The Medicare Part D benefit design contributes to making innovative therapies cost-prohibitive for Medicare patients because patients are charged out-of-pocket costs based on a medicine's list price, which does not reflect the rebates that Medicare receives. AbbVie believes it is important to alleviate the burdens that patients face due to Medicare Part D out-of-pocket costs. AbbVie supports solutions like a patient out-of-pocket cap in Part D and smoothing patient out-of-pocket payments over a full year, so patients have some predictability with respect to their out-of-pocket costs. In addition, AbbVie is prepared to step up and discuss how companies like ours can shoulder more of the burden of a patient's out- of-pocket expenses. As policymakers consider the impact of addressing out-of-pocket costs in Medicare Part D, questions may arise around whether it will lead to unnecessary utilization and wasteful spending. for specialty medicines, increased utilization should not be misunderstood as unnecessary or wasteful. Part D plans have tools, like step therapy requirements for patients to first try lower cost alternatives before a specialty medicine would be covered and prior authorization requirements before a specialty medicine would be covered, to manage the utilization of the majority of higher cost specialty medicines. These tools ensure patients try a less costly medication first and have met the clinical criteria for taking the specialty drug prescribed and serve the function that an out-of-pocket cost obligation on patients might serve to prevent unnecessary use. Question. How much does your company's research and development portfolio rely on taxpayer-funded research conducted by the National Institutes of Health (NIH)? How many of your company's products are based, at least in part, on NIH research, and how many are the result of research funded solely by your company? Answer. The NIH performs important basic research that helps scientific understanding. However, AbbVie spends its own money to do the vast majority of its drug development and clinical trial work, relying on the more than 8,000 people in research and development to understand complex diseases and advance medicine. for the eleven AbbVie drugs sold in the United States that have been approved since 2000, and the two AbbVie drugs currently under review by the FDA, only two received funding from the NIH for drug discovery. One of those drugs, Orilissa, was developed by Neurocrine. Neurocrine received NIH funding for drug development prior to AbbVie's collaboration with Neurocrine. For the second, Kaletra, AbbVie's predecessor Abbott Laboratories received an NIH discovery grant as part of an effort by the NIH to encourage collaborative research among pharmaceutical manufacturers and university research centers on protease inhibitors and to explore their potential to treat HIV, a then uncontrollable and fatal disease. This grant contributed to the development of one of the two active ingredients in the drug. This grant, however, represented less than 1 percent of the total funding for Kaletra, with more than 99 percent of the funding coming from Abbott. In addition, for AbbVie's two oncology drugs--Venclexta and Imbruvica--AbbVie has worked cooperatively with the National Cancer Institute to conduct certain clinical trials. To date, these cooperative trials have not resulted in any FDA approved indications for these drugs. Question. In each of the last 5 years, how much has your company spent on research and development versus the advertising and marketing of your products? Answer. In each of the last four years, AbbVie has spent more on research and development than it has on sales and marketing. ---------------------------------------------------------------------------------------------------------------- 2014 2015 2016 2017 2018 ---------------------------------------------------------------------------------------------------------------- AbbVie Research $3.297 billion $4.285 billion $4.385 billion $5.007 billion $5.259 billion and PDevelopment ---------------------------------------------------------------------------------------------------------------- Asset Impairments ................. ................. ................. ................. $5.070 billion ---------------------------------------------------------------------------------------------------------------- Reported Research $3.297 billion $4.285 billion $4.385 billion $5.007 billion $10.329 billion and Development ---------------------------------------------------------------------------------------------------------------- Acquired in- $352 million $150 million $200 million $327 million $424 million process Presearch and development ---------------------------------------------------------------------------------------------------------------- Global Sales and $3.652 billion $3.800 billion $3.674 billion $3.830 billion $4.239 billion PMarketing ---------------------------------------------------------------------------------------------------------------- * Sales and marketing includes the cost of AbbVie personnel in the sales and marketing field, related overhead, the cost to develop marketing and advertising materials, and the cost of placing advertisements. Question. During the hearing, you mentioned that your company would be likely to lower the list prices of its drugs if the recent proposal by the Trump administration to change the current system of rebates was extended to the private market. If the policy was extended to the private market, how large would the list price reductions be relative to the size of the rebates your company is currently providing? How will this proposal affect how your company sets the list prices for new drug products? If the proposal is finalized and not extended to the private market, will your company make any list price reductions? If so, how large would the reductions be relative to the size of the rebates your company is currently providing? Answer. There has been significant discussion over the past several months about proposals to eliminate rebates from Medicare Part D, Medicaid, and the commercial market culminating in the administration's publication of a proposed rule to ``expressly exclud[e] from safe harbor protection under the Anti-Kickback Statute (AKS) rebates on prescription drugs paid by manufacturers to pharmacy benefit managers (PBMs), Part D plans, and Medicaid managed care organizations. The proposal would create a new safe harbor protecting discounts offered to patients at the pharmacy counter. Finally, the proposal would create new safe harbor protection for fixed fee services arrangements between manufacturers and PBMs.'' AbbVie is encouraged by the goals of the proposed rule to ensure manufacturer discounts are reflected in and reduce patient cost sharing under Part D. While we believe the rule is an important step in the right direction, we also believe more should be done to help reduce the out-of-pocket cost burden on Medicare Part D patients. As for what the elimination of rebates might mean to the overall health care system or pharmaceutical companies, it is premature to comment on these items until the administration's rule is finalized, implementation timelines are solidified, and there are specific details regarding how a new system without rebates will be structured and function. ______ Question Submitted by Hon. Maggie Hassan Question. In June of 2018, the Medicaid and CHIP Payment and Access Commission (MACPAC) unanimously recommended under Recommendation 1.1 in their annual report to Congress that Congress remove the statutory requirement that manufacturers blend the average manufacturer price (AMP) of a brand drug and its authorized generic.\3\ --------------------------------------------------------------------------- \3\ MACPAC. ``Improving Operations of the Medicaid Drug Rebate Program,'' https://www.macpac.gov/wpcontent/uploads/2018/06/Improving- Operations-of-the-Medicaid-Drug-Rebate-Program.pdf. This requirement created an unintended loophole. Rather than use the price of the authorized generic, drug companies can sell its authorized generic to a corporate subsidiary at an artificially lower price, and use that lower price to bring down the AMP, which in turn --------------------------------------------------------------------------- lowers the rebate obligation. Does your company engage in this practice? Has your company ever engaged in this practice in the past? Answer. AbbVie does not engage in this practice and has not engaged in this practice in the past. AbbVie only distributes, and has only distributed, authorized generic versions of certain of its branded products through authorized generic distribution and/or supply agreements with third-parties that are wholly unrelated to AbbVie, meaning a third-party entity that is not an affiliate or subsidiary of AbbVie or otherwise owned by, controlled by, or under common control with, in whole or in part, AbbVie. Those agreements are negotiated by AbbVie and the third-party at arms-length and in good faith. ______ Questions Submitted by Hon. Catherine Cortez Masto Question. As a portion of your revenue, for what percentage of the drugs in your portfolio do you offer no rebates? Based on the drugs in your pipeline, do you foresee that portion growing? for those drugs is your list price equal to your net price? Answer. All of AbbVie's on-market medicines have some rebating/ discounting in one or multiple channels and we anticipate all of our pipeline medicines will be similar. Question. Do you invest more in R&D than you generate in US sales revenue? Please include specific figures. Answer. AbbVie spent $5.26 billion in research and development in 2018. AbbVie's research and development spend does not include acquired in-process research and development ($424 million in 2018) or money invested externally for technology, pharmaceutical compounds or acquisitions. For example, AbbVie acquired Pharmacyclics for $20.8 billion in 2015 and Stemcentrx for $6.4 billion in 2016. In 2018, the net revenues for products AbbVie sells in the United States was $21.52 billion. This includes revenues that are split with Janssen for Imbruvica. While AbbVie's U.S net revenues are higher than its research and development expense, AbbVie's global net income since it became an independent company in 2013 is less than the over $50 billion it has invested in that same time period to bring drugs to market. Question. Do you invest more in R&D than you spend on marketing and administration? What company functions do you consider to be included in administration? Please include specific figures. Answer. AbbVie spends more on research and development than on global sales, marketing, and promotion costs. The global sales, marketing, and promotion spend in 2018 across all AbbVie products was $4.24 billion. This is less than the $5.26 billion AbbVie spent on research and development in 2018. And AbbVie's research and development spend does not include acquired inprocess research and development ($424 million in 2018) or money invested externally for technology, pharmaceutical compounds or acquisitions. for example, AbbVie acquired Pharmacyclics for $20.8 billion in 2015 and Stemcentrx for $6.4 billion in 2016. However, adding the $3.16 billion spent in administration, which includes overhead costs such as corporate human resources, corporate finance, corporate ethics and compliance, corporate legal, and corporate information technology, as well as other expenses such as charitable donations, AbbVie spent a total of $7.4 billion in selling, marketing, promotion, and administrative expenses (SG&A). Question. Do you invest more in R&D than you spend on marketing and sales? What company functions do you consider to be included in sales? Please include specific figures. Answer. AbbVie spends more on research and development than on global sales, marketing, and promotion costs. The global sales, marketing, and promotion spend in 2018 across all AbbVie products was $4.24 billion. This is less than the $5.26 billion AbbVie spent on research and development in 2018. And AbbVie's research and development spend does not include acquired in-process research and development ($424 million in 2018) or money invested externally for technology, pharmaceutical compounds or acquisitions. for example, AbbVie acquired Pharmacyclics for $20.8 billion in 2015 and Stemcentrx for $6.4 billion in 2016. Sales and marketing includes the cost of AbbVie personnel in the sales and marketing field, related overhead, the cost to develop marketing and advertising materials, and the cost of placing advertisements. Question. Why do you advertise for the drugs you manufacture? What factors do you consider in choosing which drugs you advertise? Answer. Our goal in advertising is to provide those living with the conditions that our drugs treat with the best information possible so they can have an informed discussion with their health-care provider. For many patients DTC ads are an important source of information about new medicines, and advertising also plays an important role in raising awareness of diseases, removing stigma from certain conditions, and encouraging discussions with their health-care providers. ______ Exhibit 1 Grants Donations Report--2014 (Parentheses represent refunds of previously disclosed payments) Updated as of 3/31/2018 ------------------------------------------------------------------------ Recipient Payment Amount Purpose ------------------------------------------------------------------------ 100 Black Men of Atlanta, $20,000.00 Corporate Sponsorship Inc. A and R Educational Group, $5,500.00 Corporate Sponsorship LLC A Runners Love $5,000.00 Corporate Sponsorship Academia Medica Del $(240.57) Educational Grants Academia Medica Del $(309.06) Educational Grants Academia Medica Del $20,000.00 Educational Grants Academia Medica Del $15,000.00 Educational Grants Academia Medica Del $8,800.00 Educational Grants Academia Medica Del $10,000.00 Educational Grants Academia Medica Del $10,000.00 Educational Grants Academia Medica Del $10,000.00 Educational Grants Academia Medica Del $10,000.00 Educational Grants Academia Medica Del $10,000.00 Educational Grants Academia Medica Del $8,900.00 Educational Grants Academia Medica Del $5,000.00 Educational Grants Academia Medica Del $5,000.00 Educational Grants Academia Medica Del $10,000.00 Educational Grants Academia Medica Del $10,000.00 Educational Grants Academia Medica Del $20,000.00 Educational Grants Academia Medica Del $10,000.00 Educational Grants Academia Medica Del $10,000.00 Educational Grants Academia Medica Del $5,000.00 Educational Grants Academia Medica Del $10,000.00 Educational Grants Academia Medica Del $(1,539.53) Educational Grants Academia Medica Del $10,000.00 Educational Grants Academia Medica Del $15,000.00 Educational Grants Academia Medica Del $15,000.00 Educational Grants Academia Medica Del $15,000.00 Educational Grants Academia Medica Del $10,000.00 Educational Grants Academia Medica Del $5,000.00 Educational Grants Academia Medica Del $4,000.00 Educational Grants Academia Medica Del $10,000.00 Educational Grants Academia Medica Del $5,000.00 Educational Grants Academia Medica Del $5,000.00 Educational Grants Academia Medica Del $5,000.00 Educational Grants Academia Medica Del $10,000.00 Educational Grants Academia Medica Del $15,000.00 Educational Grants Academia Medica Del $10,000.00 Educational Grants Academia Medica Del $10,000.00 Educational Grants Academia Medica Del $10,000.00 Educational Grants Academia Medica Del $20,000.00 Educational Grants Academia Medica Del $15,000.00 Educational Grants Academia Medica Del $5,000.00 Educational Grants Academy of Managed Care $50,000.00 Corporate Sponsorship Pharmacy Advances in Cosmetic and $50,000.00 Corporate Sponsorship Medical Dermatology, Inc. Advances in Cosmetic and $50,000.00 Corporate Sponsorship Medical Dermatology, Inc. Advances in Cosmetic and $100,000.00 Corporate Sponsorship Medical Dermatology, Inc. Advances in Targeted $150,000.00 Corporate Sponsorship Therapies Advocate Health and $2,500.00 Educational Grants Hospitals Corporation AIDS Drug Assistance $2,500.00 Corporate Sponsorship Programs Advocacy Association AIDS Drug Assistance $10,000.00 Educational Grants Programs Advocacy Association AIDS Drug Assistance $5,000.00 Corporate Sponsorship Programs Advocacy Association AIDS Foundation of Chicago $125,000.00 Charitable Donations AIDS Foundation of Chicago $7,500.00 Charitable Donations AIDS Project Los Angeles $5,000.00 Educational Grants Alaska Kidney Patients $1,500.00 Patient Support Association Albert Einstein College of $20,000.00 Educational Grants Medicine of Yeshiva University Albert Einstein College of $5,000.00 Educational Grants Medicine of Yeshiva University Albert Einstein College of $10,000.00 Educational Grants Medicine, Division of Dermatology Attending Association Albert Einstein Healthcare $2,500.00 Educational Grants Network Albert Einstein Healthcare $6,500.00 Corporate Sponsorship Network Alchemy Communications $50,000.00 Corporate Sponsorship Group, LLC Alliance Foundation for $75,000.00 Educational Grants Continuing Education in the Health Professions Alzheimer's Association $50,000.00 Corporate Sponsorship American Academy of $(8,842.31) Educational Grants Continuing Medical Education, Inc. American Academy of $25,000.00 Educational Grants Continuing Medical Education, Inc. American Academy of $75,000.00 Corporate Sponsorship Dermatology American Academy of $50,000.00 Educational Grants Dermatology American Academy of $100,000.00 Corporate Sponsorship Dermatology American Academy of $35,000.00 Corporate Sponsorship Dermatology American Academy of $10,000.00 Charitable Donations Neurology Foundation American Academy of $45,000.00 Educational Grants Physician Assistants American Academy of $10,000.00 Educational Grants Physician Assistants American Academy of Urology $3,000.00 Educational Grants Institute--AANI American Association for $10,000.00 Educational Grants Cancer Research American Association for $10,000.00 Educational Grants Cancer Research American Association for $20,000.00 Charitable Donations Laboratory Animal Science Foundation American Association for $500,000.00 Charitable Donations the Study of Liver Diseases American Association for $7,000.00 Corporate Sponsorship the Study of Liver Diseases American Association for $500,000.00 Charitable Donations the Study of Liver Diseases American Association for $137,500.00 Corporate Sponsorship the Study of Liver Diseases American Association of $25,000.00 Educational Grants Clinical Endocrinologists American Association of $25,000.00 Educational Grants Clinical Endocrinologists American Association of $50,000.00 Educational Grants Kidney Patients American Association of $10,000.00 Patient Support Kidney Patients American Association of $25,000.00 Corporate Sponsorship Pharmaceutical Scientists American Brain Tumor $10,000.00 Corporate Sponsorship Association American Chemical Society $1,000.00 Educational Grants American College of $7,500.00 Educational Grants Clinical Pharmacology American College of $321,900.00 Corporate Sponsorship Endocrinology American College of $100,000.00 Corporate Sponsorship Gastroenterology American College of $20,000.00 Corporate Sponsorship Gastroenterology American College of $85,000.00 Corporate Sponsorship Gastroenterology American College of $25,000.00 Charitable Donations Laboratory Animal Medicine American College of $55,000.00 Corporate Sponsorship Physicians Foundation American College of $55,000.00 Corporate Sponsorship Physicians Foundation American College of $55,000.00 Corporate Sponsorship Physicians Foundation American College of $100,000.00 Corporate Sponsorship Rheumatology American College of $200,000.00 Fellowships and Rheumatology Scholarships American College of $75,000.00 Educational Grants Rheumatology American College of $50,000.00 Educational Grants Rheumatology American College of $25,000.00 Educational Grants Rheumatology American College of $25,000.00 Educational Grants Rheumatology American College of $100,000.00 Corporate Sponsorship Rheumatology American College of $2,000,000.00 Corporate Sponsorship Rheumatology Research and Education Foundation American College of $5,000.00 Corporate Sponsorship Veterinary Pathologists American $303,800.00 Educational Grants Gastroenterological Association Institute American $7,000.00 Corporate Sponsorship Gastroenterological Association Institute American $225,000.00 Educational Grants Gastroenterological Association Institute American $100,000.00 Corporate Sponsorship Gastroenterological Association Institute American Health Resources $2,000.00 Educational Grants American Kidney Fund $5,000.00 Corporate Sponsorship American Liver Foundation $10,000.00 Charitable Donations American Liver Foundation $10,000.00 Corporate Sponsorship American Liver Foundation $5,000.00 Corporate Sponsorship American Liver Foundation $10,000.00 Corporate Sponsorship American Liver Foundation $6,000.00 Corporate Sponsorship American Liver Foundation $2,000.00 Corporate Sponsorship American Liver Foundation $5,000.00 Corporate Sponsorship American Liver Foundation $5,000.00 Corporate Sponsorship American Liver Foundation $5,000.00 Charitable Donations American Liver Foundation $10,000.00 Corporate Sponsorship American Liver Foundation $2,500.00 Corporate Sponsorship American Liver Foundation $5,000.00 Corporate Sponsorship American Liver Foundation $127,000.00 Corporate Sponsorship American Liver Foundation $106,000.00 Corporate Sponsorship American Liver Foundation $5,000.00 Educational Grants American Liver Foundation $2,500.00 Corporate Sponsorship American Medical Group $6,000.00 Corporate Sponsorship Association American Medical Group $6,000.00 Corporate Sponsorship Association American Medical Group $5,050.00 Corporate Sponsorship Association American Medical Group $5,050.00 Corporate Sponsorship Association American Medical Group $5,050.00 Corporate Sponsorship Association American Medical Group $5,050.00 Corporate Sponsorship Association American Medical Group $5,050.00 Corporate Sponsorship Association American Nephrology Nurses $2,500.00 Fellowships and Association Scholarships American Neurological $25,000.00 Educational Grants Association American Pancreatic $15,000.00 Charitable Donations Association American Pancreatic $75,000.00 Educational Grants Association American Pancreatic $35,000.00 Corporate Sponsorship Association American Parkinson Disease $2,000.00 Educational Grants Association, Inc., Georgia Chapter American Physiological $2,000.00 Educational Grants Society American Skin Association $15,000.00 Corporate Sponsorship American Society for $7,000.00 Corporate Sponsorship Gastrointestinal Endoscopy American Society for Mens $27,000.00 Corporate Sponsorship Health, The American Society for Mens $50,000.00 Corporate Sponsorship Health, The American Society for Mens $60,000.00 Corporate Sponsorship Health, The American Society for $23,500.00 Corporate Sponsorship Microbiology American Society for $23,500.00 Corporate Sponsorship Microbiology American Society of $5,000.00 Corporate Sponsorship Andrology American Society of $25,000.00 Educational Grants Clinical Oncology American Society of $4,500.00 Corporate Sponsorship Clinical Rheumatologists American Society of $15,000.00 Educational Grants Hematology American Society of $75,000.00 Corporate Sponsorship Hematology American Society of $30,000.00 Educational Grants Nephrology American Statistical $4,225.00 Corporate Sponsorship Association American Thyroid $25,000.00 Educational Grants Association, Inc. American Uroligical $12,300.00 Corporate Sponsorship Association, Northeastern Section American Urological $20,000.00 Educational Grants Association Education and Research, Inc. American Urological $70,000.00 Educational Grants Association Education and Research, Inc. American Urological $75,000.00 Educational Grants Association Education and Research, Inc. American Urological $50,000.00 Educational Grants Association Education and Research, Inc. American Urological $30,000.00 Educational Grants Association Education and Research, Inc. American Urological $10,000.00 Educational Grants Association Education and Research, Inc. American Urological $10,000.00 Educational Grants Association Education and Research, Inc. American Urological $25,000.00 Educational Grants Association Education and Research, Inc. American Urological $10,000.00 Educational Grants Association Education and Research, Inc. American Urological $25,000.00 Educational Grants Association Education and Research, Inc. American Urological $70,000.00 Corporate Sponsorship Association Foundation American Urological $6,000.00 Corporate Sponsorship , Association Inc. Southeast Section American Urological $6,000.00 Corporate Sponsorship Association, Inc. North Central Section American Urological $10,000.00 Corporate Sponsorship Association, Inc. Western Section American Urological $10,000.00 Educational Grants Association, Mid-Atlantic Section, Education Fund, Inc. American Urological $10,000.00 Educational Grants Association, New England American Urological $1,000.00 Corporate Sponsorship Association, New York Section American Urological $6,000.00 Corporate Sponsorship Association, South Central Section Americas Committee for $10,000.00 Corporate Sponsorship Treatment And Research In Multiple Sclerosis Anesthesia Patient Safety $25,000.00 Charitable Donations Foundation Angel Wings Foundation $750.00 Corporate Sponsorship Ann & Robert H. Lurie $10,000.00 Corporate Sponsorship Children's Hospital of Chicago Annenberg Center for Health $50,000.00 Educational Grants Sciences at Eisenhower Annenberg Center for Health $125,000.00 Educational Grants Sciences at Eisenhower Annenberg Center for Health $35,000.00 Educational Grants Sciences at Eisenhower Annenberg Center for Health $65,000.00 Educational Grants Sciences at Eisenhower Arthritis Foundation $20,000.00 Corporate Sponsorship Arthritis Foundation $8,000.00 Corporate Sponsorship Arthritis Foundation $28,500.00 Corporate Sponsorship Arthritis Foundation $25,000.00 Corporate Sponsorship Arthritis Foundation $5,000.00 Charitable Donations Arthritis Foundation $5,000.00 Patient Support Arthritis Foundation $5,000.00 Charitable Donations Arthritis Foundation $5,000.00 Corporate Sponsorship Central, Pennsylvania Chapter Arthritis Foundation New $10,000.00 Corporate Sponsorship England Arthritis Foundation, $225,000.00 Corporate Sponsorship Alabama Chapter Arthritis Foundation, $250,000.00 Corporate Sponsorship Alabama Chapter Arthritis Foundation, $175,000.00 Corporate Sponsorship Alabama Chapter Arthritis Foundation, $65,000.00 Patient Support Alabama Chapter Arthritis Foundation, $17,000.00 Corporate Sponsorship Alabama Chapter Arthritis Foundation, $2,500.00 Corporate Sponsorship Alabama Chapter Arthritis Foundation, $259,000.00 Corporate Sponsorship Alabama Chapter Arthritis Foundation, $175,000.00 Corporate Sponsorship Alabama Chapter Arthritis Foundation, $35,000.00 Corporate Sponsorship Alabama Chapter Arthritis Foundation, $250,000.00 Corporate Sponsorship Alabama Chapter Arthritis Foundation, Great $3,000.00 Patient Support Lakes Region Arthritis Foundation, Great $2,500.00 Patient Support Lakes Region Arthritis Foundation, Great $2,500.00 Patient Support Lakes Region Arthritis Foundation, Great $35,500.00 Corporate Sponsorship Lakes Region Arthritis Foundation, Great $20,000.00 Charitable Donations Lakes Region Arthritis Foundation, Great $5,000.00 Charitable Donations Lakes Region Arthritis Foundation, Great $12,500.00 Charitable Donations Lakes Region Arthritis Foundation, Great $3,000.00 Charitable Donations Lakes Region Arthritis Foundation, Great $2,250.00 Patient Support Lakes Region Arthritis Foundation, Great $2,250.00 Patient Support Lakes Region Arthritis Foundation, Great $3,000.00 Patient Support Lakes Region Arthritis Foundation, Great $2,250.00 Patient Support Lakes Region Arthritis Foundation, Great $2,250.00 Patient Support Lakes Region Arthritis Foundation, Great $1,000.00 Patient Support Lakes Region Arthritis Foundation, Great $35,000.00 Corporate Sponsorship West Region Arthritis Foundation, Great $28,000.00 Corporate Sponsorship West Region Arthritis Foundation, Great $10,000.00 Charitable Donations West Region Arthritis Foundation, $21,000.00 Corporate Sponsorship Massachusetts Chapter Arthritis Foundation, $1,853.94 Patient Support Massachusetts Chapter Arthritis Foundation, $3,000.00 Corporate Sponsorship Massachusetts Chapter Arthritis Foundation, $3,000.00 Corporate Sponsorship Massachusetts Chapter Arthritis Foundation, Mid $15,000.00 Corporate Sponsorship Atlantic Region Arthritis Foundation, Mid $1,500.00 Educational Grants Atlantic Region Arthritis Foundation, Mid $1,000.00 Patient Support Atlantic Region Arthritis Foundation, South $14,000.00 Corporate Sponsorship Texas Chapter Arthritis Foundation, South $2,500.00 Charitable Donations Texas Chapter Arthritis Foundation, $65,000.00 Corporate Sponsorship Southern California Chapter Arthritis Foundation, $2,500.00 Charitable Donations Southern California Chapter Arthritis Foundation, $2,500.00 Charitable Donations Southern California Chapter Arthritis Foundation, $5,000.00 Corporate Sponsorship Southern California Chapter Arthritis Foundation, $7,000.00 Corporate Sponsorship Wisconsin Chapter Arthritis Patient Services $10,000.00 Educational Grants Arthritis Patient Services $25,000.00 Educational Grants ASCO Cancer Foundation $50,000.00 Charitable Donations ASCO Cancer Foundation $40,000.00 Fellowships and Scholarships ASCO Cancer Foundation $28,000.00 Educational Grants Asociacion de Reumatologos $15,000.00 Corporate Sponsorship de Puerto Rico Asociacion Nacional de $4,000.00 Corporate Sponsorship Tecnicos de Farmacia, Inc. Asociacion Puertorriquena $1,200.00 Corporate Sponsorship de Ayuda al Paciente de Psoriasis Association of Dermatology $7,500.00 Corporate Sponsorship Administrators And Managers Association of Nurses in $15,000.00 Educational Grants AIDS Care, Chicago Chapter Association of Physicians $2,500.00 Corporate Sponsorship of Pakistani-Descent of North America Balm In Gilead Inc. $75,000.00 Corporate Sponsorship Baylor College of Medicine $5,000.00 Educational Grants Baylor University Medical $67,716.00 Educational Grants Center Baylor University Medical $29,340.00 Educational Grants Center Beth Israel Deaconess $50,000.00 Fellowships and Department of Medicine Scholarships Foundation Beth Israel Deaconess $(1,948.24) Educational Grants Medical Center Beth Israel Deaconess $40,000.00 Fellowships and Medical Center Scholarships Billings Clinic $5,000.00 Corporate Sponsorship Bioconnections, LLC $15,000.00 Corporate Sponsorship Biophysical Society $2,500.00 Educational Grants Blank Children's Hospital $2,500.00 Corporate Sponsorship Board of Regents of the $5,000.00 Educational Grants University of Wisconsin System Board of Trustees of the $1,500.00 Educational Grants University of Illinois Board of Trustees of The $40,000.00 Fellowships and University of Illinois, Scholarships The Board of Trustees of The $30,000.00 Fellowships and University of Illinois, Scholarships The Boomer Esiason Foundation $1,200.00 Corporate Sponsorship Boomer Esiason Foundation $100,000.00 Educational Grants Boomer Esiason Foundation $75,000.00 Charitable Donations Boomer Esiason Foundation $400,000.00 Corporate Sponsorship Boomer Esiason Foundation $25,000.00 Corporate Sponsorship Boomer Esiason Foundation $400,000.00 Corporate Sponsorship Boston Society, Inc. $4,000.00 Corporate Sponsorship Boston Society, Inc. $4,000.00 Corporate Sponsorship Boston University School of $124,943.00 Educational Grants Medicine Brigham and Women's $(50,000.00) Fellowships and Hospital, Inc. Scholarships Brigham and Women's $50,000.00 Fellowships and Hospital, Inc. Scholarships California Rheumatology $30,000.00 Corporate Sponsorship Alliance California Separation $60,000.00 Corporate Sponsorship Science Society California Society of $3,000.00 Corporate Sponsorship Health System Pharmacists California Society of $5,000.00 Corporate Sponsorship Health System Pharmacists California Society of $3,000.00 Corporate Sponsorship Health System Pharmacists Campaign for Public Health $10,000.00 Charitable Donations Foundation Cancer and Leukemia Group B $20,000.00 Educational Grants Foundation Cancer Molecular $5,000.00 Educational Grants Therapeutics Case Western Reserve $25,000.00 Educational Grants University Cedars-Sinai Medical Center $40,000.00 Educational Grants Cedars-Sinai Medical Center $10,000.00 Educational Grants Cedars-Sinai Medical Center $40,000.00 Fellowships and Scholarships Central Florida Pharmacy $25,000.00 Educational Grants Council, Inc. Central Ohio Parkinson $20,000.00 Educational Grants Society DBA National Parkinson Foundation Central and Southeast Ohio Chelsea Hutchinson $2,500.00 Corporate Sponsorship Foundation The Children and Arthritis, $5,000.00 Charitable Donations Inc. Children's Digestive Health $40,000.00 Fellowships and and Nutrition Foundation Scholarships Children's Digestive Health $25,000.00 Educational Grants and Nutrition Foundation Children's Digestive Health $40,000.00 Fellowships and and Nutrition Foundation Scholarships Children's Digestive Health $10,000.00 Corporate Sponsorship and Nutrition Foundation Children's Hospital Medical $20,000.00 Corporate Sponsorship Center Children's Hospital Medical $40,000.00 Fellowships and Center Scholarships Children's Hospital Medical $20,000.00 Corporate Sponsorship Center Children's Oncology $5,500.00 Corporate Sponsorship Services Inc. Chimp Haven $50,000.00 Charitable Donations Chris Dudley Foundation $5,000.00 Corporate Sponsorship Chronic Liver Disease $211,000.00 Educational Grants Foundation Chronic Liver Disease $211,670.00 Educational Grants Foundation Chronic Liver Disease $1,300,000.00 Educational Grants Foundation Chronic Liver Disease $7,500.00 Corporate Sponsorship Foundation Cleveland Clinic $(1,340.00) Educational Grants Cleveland Clinic $10,000.00 Educational Grants Educational Foundation, The Cleveland Clinic $25,000.00 Educational Grants Educational Foundation, The Cleveland Clinic $75,000.00 Educational Grants Educational Foundation, The Cleveland Clinic $4,500.00 Educational Grants Educational Foundation, The Cleveland Clinic $(2,033.31) Educational Grants Educational Foundation, The Cleveland Clinic $75,000.00 Educational Grants Educational Foundation, The Cleveland Clinic $15,000.00 Educational Grants Educational Foundation, The Cleveland Clinic $385,000.00 Educational Grants Educational Foundation, The Cleveland Clinic $132,000.00 Educational Grants Educational Foundation, The Cleveland Clinic $15,000.00 Educational Grants Educational Foundation, The Cleveland Clinic $5,000.00 Educational Grants Educational Foundation, The Cleveland Clinic $(2,638.82) Educational Grants Educational Foundation, The Cleveland Clinic $75,000.00 Educational Grants Educational Foundation, The Cleveland Clinic $5,000.00 Educational Grants Educational Foundation, The Cleveland Clinic Foundation $50,000.00 Fellowships and Scholarships Cleveland Clinic Foundation $50,000.00 Fellowships and Scholarships Clinical Care Options, LLC $75,000.00 Educational Grants Clinical Care Options, LLC $150,000.00 Educational Grants Clinical Care Options, LLC $50,000.00 Educational Grants Clinical Care Options, LLC $25,000.00 Educational Grants Clinical Care Options, LLC $100,000.00 Educational Grants Clinical Care Options, LLC $209,000.00 Educational Grants CME Incite, LLC $(175,000.00) Educational Grants Coalition for Prevention of $5,000.00 Corporate Sponsorship Colorectal Cancer in Puerto Rico Coalition on Positive $125,000.00 Patient Support Health Empowerment Colegio Medicos-Cirujanos $20,000.00 Educational Grants P.R Com & Co Sarl $3,550.00 Corporate Sponsorship Community Health $10,000.00 Corporate Sponsorship Community Initiatives $10,000.00 Corporate Sponsorship Community Liver Alliance $3,000.00 Corporate Sponsorship Community Liver Alliance $1,000.00 Corporate Sponsorship Community Liver Alliance $5,000.00 Corporate Sponsorship Community Liver Alliance $150,000.00 Educational Grants Complete Conference $50,000.00 Educational Grants Management Complete Conference $75,000.00 Educational Grants Management Complete Conference $(75,000.00) Educational Grants Management Complete Conference $(75,000.00) Educational Grants Management Consortium of Multiple $25,000.00 Educational Grants Sclerosis Centers Continuing Educational $(703.13) Educational Grants Alliance, LLC Continuing Educational $362,500.00 Educational Grants Alliance, LLC Continuing Educational $(210.66) Educational Grants Alliance, LLC Continuing Educational $(258.18) Educational Grants Alliance, LLC Continuing Educational $(1,696.48) Educational Grants Alliance, LLC Continuing Medical $85,000.00 Educational Grants Education Outfitters, LLC Continuous Renal $10,000.00 Educational Grants Replacement Therapies, Inc. (CRRT) Cornell University, Weill $5,000.00 Educational Grants Medical College Cornerstone Health, Inc. $(3,664.00) Educational Grants Cornerstone Health, Inc. $200,000.00 Educational Grants Cornerstone Health, Inc. $175,000.00 Educational Grants Cornerstone Health, Inc. $40,000.00 Educational Grants Cornerstone Health, Inc. $100,000.00 Educational Grants Creighton University $2,220.00 Charitable Donations Crohn's and Colitis $2,500.00 Corporate Sponsorship Foundation of America Crohn's and Colitis $22,500.00 Corporate Sponsorship Foundation of America Crohn's and Colitis $350,000.00 Corporate Sponsorship Foundation of America Crohn's and Colitis $100,000.00 Corporate Sponsorship Foundation of America Crohn's and Colitis $20,000.00 Corporate Sponsorship Foundation of America Crohn's and Colitis $9,000.00 Educational Grants Foundation of America Crohn's and Colitis $6,000.00 Patient Support Foundation of America Crohn's and Colitis $80,000.00 Corporate Sponsorship Foundation of America Crohn's and Colitis $9,000.00 Patient Support Foundation of America Crohn's and Colitis $6,200.00 Patient Support Foundation of America Crohn's and Colitis $4,000.00 Patient Support Foundation of America Crohn's and Colitis $(3,095.00) Educational Grants Foundation of America Crohn's and Colitis $65,000.00 Educational Grants Foundation of America Crohn's and Colitis $3,000.00 Educational Grants Foundation of America Crohn's and Colitis $10,000.00 Patient Support Foundation of America Crohn's and Colitis $1,000.00 Corporate Sponsorship Foundation of America Crohn's and Colitis $25,000.00 Charitable Donations Foundation of America Crohn's and Colitis $2,000.00 Corporate Sponsorship Foundation of America Crohn's and Colitis $100,000.00 Educational Grants Foundation of America Crohn's and Colitis $8,000.00 Educational Grants Foundation of America Crohn's and Colitis $2,000.00 Corporate Sponsorship Foundation of America Crohn's and Colitis $5,000.00 Corporate Sponsorship Foundation of America Crohn's and Colitis $2,500.00 Corporate Sponsorship Foundation of America Crohn's and Colitis $3,500.00 Patient Support Foundation of America Crohn's and Colitis $100,000.00 Fellowships and Foundation of America Scholarships Crohn's and Colitis $3,000.00 Patient Support Foundation of America Crohn's and Colitis $5,000.00 Corporate Sponsorship Foundation of America Crohn's and Colitis $1,500.00 Corporate Sponsorship Foundation of America Crohn's and Colitis $10,000.00 Educational Grants Foundation of America Crohn's and Colitis $65,000.00 Educational Grants Foundation of America Crohn's and Colitis $25,000.00 Charitable Donations Foundation of America Crohn's and Colitis $100,000.00 Educational Grants Foundation of America Curatio CME Institute $(100,000.00) Educational Grants Cystic Fibrosis--Reaching $25,000.00 Charitable Donations Out Foundation Cystic Fibrosis Foundation-- $5,000.00 Corporate Sponsorship Albany Cystic Fibrosis Foundation-- $3,500.00 Corporate Sponsorship Albany Cystic Fibrosis Foundation-- $1,000.00 Corporate Sponsorship Albany Cystic Fibrosis Foundation-- $100,000.00 Charitable Donations Albany Cystic Fibrosis Foundation-- $2,000.00 Corporate Sponsorship Albany Cystic Fibrosis Foundation-- $5,000.00 Corporate Sponsorship Albany Cystic Fibrosis Foundation-- $10,000.00 Corporate Sponsorship Albany Cystic Fibrosis Foundation-- $4,000.00 Corporate Sponsorship Albany Cystic Fibrosis Foundation-- $10,000.00 Corporate Sponsorship Albany Cystic Fibrosis Foundation-- $2,000.00 Corporate Sponsorship Albany Cystic Fibrosis Foundation-- $3,000.00 Corporate Sponsorship Albany Cystic Fibrosis Foundation-- $1,000.00 Corporate Sponsorship Albany Cystic Fibrosis Foundation-- $2,500.00 Corporate Sponsorship Albany Cystic Fibrosis Foundation-- $1,500.00 Corporate Sponsorship Albany Cystic Fibrosis Foundation-- $2,500.00 Corporate Sponsorship Albany Cystic Fibrosis Foundation-- $2,500.00 Corporate Sponsorship Albany Cystic Fibrosis Foundation-- $25,000.00 Corporate Sponsorship Albany Cystic Fibrosis Foundation-- $1,500.00 Corporate Sponsorship Albany Cystic Fibrosis Foundation-- $1,500.00 Corporate Sponsorship Albany Cystic Fibrosis Foundation-- $1,000.00 Corporate Sponsorship Albany Cystic Fibrosis Foundation-- $1,000.00 Corporate Sponsorship Albany Cystic Fibrosis Foundation-- $15,000.00 Corporate Sponsorship Albany Cystic Fibrosis Research, $500.00 Corporate Sponsorship Inc. Cystic Fibrosis Research, $10,000.00 Educational Grants Inc. Cystic Fibrosis Research, $9,000.00 Patient Support Inc. Cystic Fibrosis Research, $5,000.00 Corporate Sponsorship Inc. Cystic Fibrosis Research, $5,000.00 Corporate Sponsorship Inc. Cystic Fibrosis Research, $15,000.00 Charitable Donations Inc. Cystic Fibrosis Research, $10,000.00 Corporate Sponsorship Inc. Dade County Medical $10,000.00 Educational Grants Association Dallas fort Worth Business $5,000.00 Corporate Sponsorship Group on Health Davis Phinney Foundation $30,000.00 Educational Grants Davis Phinney Foundation $75,000.00 Educational Grants Davis Phinney Foundation $15,000.00 Educational Grants Davis Phinney Foundation $30,000.00 Educational Grants Decatur General Hospital $2,500.00 Corporate Sponsorship Foundation Dermatology Education $15,000.00 Corporate Sponsorship Foundation Dermatology Foundation $50,000.00 Corporate Sponsorship Diversity And Leadership $5,000.00 Corporate Sponsorship Inc. Duke University $6,550.00 Educational Grants Duke University $250,000.00 Educational Grants Duke University $150,000.00 Educational Grants Duke University $50,000.00 Fellowships and Scholarships Duke University $(3,061.96) Educational Grants Educational Review Systems $10,000.00 Educational Grants Elizabeth Glaser Pediatric $10,000.00 Charitable Donations AIDS Foundation Elsevier, Inc. $70,000.00 Educational Grants Employers Health Colition $4,000.00 Corporate Sponsorship Inc. Endocrine Education, Inc $25,000.00 Educational Grants Endocrine Nurses Society $4,000.00 Corporate Sponsorship Endocrine Society, The $25,000.00 Educational Grants Endocrine Society, The $150,000.00 Educational Grants Endometriosis Association $10,000.00 Charitable Donations Engineering Conferences $1,000.00 Educational Grants International Enzyme Mechanisms $1,500.00 Educational Grants Conference Epilepsy Foundation $80,000.00 Charitable Donations ERA-Eurocongress, Ltd. $25,000.00 Corporate Sponsorship ERA-Eurocongress, Ltd. $15,000.00 Corporate Sponsorship Escuela De Medicina De $10,000.00 Educational Grants Ponce Escuela De Medicina De $10,000.00 Educational Grants Ponce European Society for $250,000.00 Corporate Sponsorship Dermatological Research European Society for $10,000.00 Corporate Sponsorship Medical Oncology Excel Continuing Education $8,225.00 Educational Grants Excellence in Rheumatology $100,000.00 Corporate Sponsorship Education, LLC Facing Our Risk of Cancer $25,000.00 Charitable Donations Empowerement Facing Our Risk of Cancer $5,000.00 Corporate Sponsorship Empowerement (FORCE) Federation of American $1,500.00 Educational Grants Societies for Experimental Biology Federation of American $1,500.00 Educational Grants Societies for Experimental Biology Federation of American $5,000.00 Corporate Sponsorship Societies for Experimental Biology Federation of Clinical $20,000.00 Educational Grants Immunology Societies Federation of Clinical $15,000.00 Educational Grants Immunology Societies Federation of Clinical $20,000.00 Educational Grants Immunology Societies Florida Academy of $8,300.00 Educational Grants Physician Assistants Florida Health Care $1,500.00 Corporate Sponsorship Coalition Foundation for Anesthesia $20,000.00 Fellowships and Education and Research Scholarships Foundation for Biomedical $120,000.00 Charitable Donations Research Foundation for Indiana $2,220.00 Charitable Donations University of Pennsylvania Foundation for Indiana $2,220.00 Charitable Donations University of Pennsylvania Foundation for Men's $50,000.00 Corporate Sponsorship Health, Inc Foundation for the National $400,000.00 Corporate Sponsorship Institutes of Health Friends of Prentice $10,000.00 Corporate Sponsorship Friends of the St. Louis $50,000.00 Corporate Sponsorship University Liver Center Fundacion Puertorriquena De $7,500.00 Educational Grants Pacientes Con Endometriosis Gastrointestinal Health $150,000.00 Educational Grants Foundation, Inc. Gastrointestinal Health $50,000.00 Educational Grants Foundation, Inc. Gastrointestinal Health $75,000.00 Corporate Sponsorship Foundation, Inc. Gastro-Intestinal Research $15,000.00 Charitable Donations Foundation Gastro-Intestinal Research $1,000.00 Corporate Sponsorship Foundation Gastro-Intestinal Research $6,600.00 Corporate Sponsorship Foundation Gastro-Intestinal Research $1,500.00 Corporate Sponsorship Foundation Gateway for Cancer Research $6,000.00 Charitable Donations Gay City Health Project $10,000.00 Charitable Donations Georgia ObGyn Society $2,500.00 Corporate Sponsorship Georgia Prostate Cancer $4,000.00 Patient Support Coalition, The Georgia Society of $3,000.00 Corporate Sponsorship Dermatology and Dermatologic Surgery Gilda's Club Chicago $10,000.00 Charitable Donations Gilda's Club New York City $50,000.00 Charitable Donations Globalization of $10,000.00 Corporate Sponsorship Pharmaceutics Education Network Gordon Research Conferences $1,500.00 Educational Grants Gordon Research Conferences $1,500.00 Educational Grants Gordon Research Conferences $1,500.00 Educational Grants Gordon Research Conferences $1,500.00 Educational Grants Gordon Research Conferences $1,500.00 Educational Grants Gordon Research Conferences $1,500.00 Educational Grants Gordon Research Conferences $1,500.00 Educational Grants Gordon Research Conferences $1,500.00 Educational Grants Gordon Research Conferences $1,500.00 Educational Grants Gordon Research Conferences $1,500.00 Educational Grants Gordon Research Conferences $2,000.00 Educational Grants Grupo de Apoyo de Ninos y $3,000.00 Corporate Sponsorship Adolescentes con Reumatologia Gynecologic Oncology Group, $25,000.00 Educational Grants The $7 $23,000.00 Educational Grants Haymarket Center-Health $5,000.00 Educational Grants Education Haymarket Medical Education $243,190.00 Educational Grants Health Sciences Foundation $2,500.00 Educational Grants dba South East AHEC Healthcare Businesswomen's $5,000.00 Corporate Sponsorship Association, Inc. Healthcare Financial $50,000.00 Corporate Sponsorship Management Association Hep C Connection $50,000.00 Educational Grants Hep C Connection $40,000.00 Patient Support Hep C Connection $5,000.00 Corporate Sponsorship Hepatitis C Association $45,000.00 Educational Grants Hepatitis C Mentor and $10,000.00 Patient Support Support Group, The Hepatitis Education Project $100,000.00 Charitable Donations HIV Treaters Medical $10,000.00 Educational Grants Association of Puerto Rico Hope Foundation, The $10,000.00 Educational Grants Housing Works, Inc. $10,000.00 Charitable Donations Howard Brown Health Center $25,000.00 Corporate Sponsorship Howard Center Inc. $10,000.00 Charitable Donations Howard University Hospital $10,000.00 Educational Grants Hubbard Street Dance $10,000.00 Educational Grants Chicago Human Growth Foundation $2,000.00 Corporate Sponsorship IDSA Education and Research $10,000.00 Fellowships and Foundation Scholarships Imedex, LLC $20,000.00 Educational Grants Imedex, LLC $75,000.00 Educational Grants Imedex, LLC $15,000.00 Educational Grants Imedex, LLC $25,000.00 Educational Grants Imedex, LLC $60,000.00 Educational Grants Impact Education, LLC $125,000.00 Educational Grants Indiana Chamber of Commerce $2,500.00 Corporate Sponsorship Indiana Chamber of Commerce $1,500.00 Corporate Sponsorship Indiana University $2,500.00 Fellowships and Scholarships Induniv Research $2,000.00 Corporate Sponsorship Infectious Diseases Society $35,000.00 Educational Grants of America Inflammatory Bowel Disease $300,000.00 Educational Grants Support Foundation Inflammatory Bowel Disease $50,000.00 Educational Grants Support Foundation Inflammatory Bowel Disease $200,000.00 Educational Grants Support Foundation Inflammatory Bowel Disease $200,000.00 Educational Grants Support Foundation Innovation Development $250,000.00 Corporate Sponsorship Institute, Inc. Institute for Medical and $10,000.00 Educational Grants Nursing Education, Inc. Integrated Benefits $35,000.00 Corporate Sponsorship Institute, Inc. Integrated Medical $50,000.00 Charitable Donations Foundation Integrated Medical $5,000.00 Corporate Sponsorship Foundation Integrated Medical $35,000.00 Charitable Donations Foundation Interfaith House $2,000.00 Charitable Donations Intermountain Dermatology $20,000.00 Educational Grants Society International AIDS Society-- $100,000.00 Educational Grants USA International AIDS Society-- $100,000.00 Educational Grants USA International AIDS Society-- $75,000.00 Educational Grants USA International Alliance for $3,000.00 Educational Grants Biologicals International Association $10,000.00 Educational Grants of Physicians in AIDS Care International Association $25,000.00 Educational Grants of Physicians in AIDS Care International Chemical $2,000.00 Educational Grants Biology Society International Pelvic Pain $7,500.00 Educational Grants Society International Psoriasis $100,000.00 Corporate Sponsorship Council, The International Psoriasis $50,000.00 Corporate Sponsorship Council, The International Society for $5,000.00 Educational Grants Antiviral Research International Society for $10,000.00 Corporate Sponsorship Medical Publication Professionals International Society for $3,000.00 Educational Grants the Study of Xenobiotics International Society of $50,000.00 Charitable Donations Nephrology International Society of $40,000.00 Charitable Donations Nephrology International Society of $175,000.00 Corporate Sponsorship Nephrology Jefferson Medical College $3,000.00 Corporate Sponsorship at Thomas Jefferson University Jefferson Medical College $30,000.00 Educational Grants at Thomas Jefferson University Jefferson Medical College $5,000.00 Educational Grants at Thomas Jefferson University John Hopkins University $(1,706.15) Educational Grants School of Medicine Johns Hopkins University $225,000.00 Educational Grants School of Medicine Johns Hopkins University $25,000.00 Educational Grants School of Medicine Johns Hopkins University $(60,000.00) Educational Grants School of Medicine Johns Hopkins University $30,000.00 Educational Grants School of Medicine Johns Hopkins University $50,000.00 Fellowships and School of Medicine Scholarships Johns Hopkins University $95,000.00 Educational Grants School of Medicine Johns Hopkins University $5,000.00 Educational Grants School of Medicine Joint Township District $4,064.00 Patient Support Memorial Hospital Joint Township District $(1,508.00) Patient Support Memorial Hospital JWC Covenant, Inc. $35,000.00 Educational Grants Kansas University $25,000.00 Educational Grants Neurological Foundation Kansas University $35,000.00 Educational Grants Neurological Foundation Kelsey Research Foundation $40,000.00 Fellowships and Scholarships Kenes International Ltd. $35,000.00 Corporate Sponsorship Kidney Disease Improving $40,128.00 Corporate Sponsorship Global Outcomes KnowledgePoint360 Group, $94,785.30 Corporate Sponsorship LLC Laboratorio Clinico Toledo $2,460.00 Patient Support Laboratorio Clinico Toledo $795.00 Patient Support Laboratorio Clinico Toledo $345.00 Patient Support Laboratorio Clinico Toledo $2,760.00 Patient Support Laboratorio Clinico Toledo $2,145.00 Patient Support Laboratorio Clinico Toledo $615.00 Patient Support Laboratorio Clinico Toledo $2,160.00 Patient Support Laboratorio Clinico Toledo $2,115.00 Patient Support Laboratorio Clinico Toledo $1,380.00 Patient Support Laboratorio Clinico Toledo $4,260.00 Patient Support Laboratorio Clinico Toledo $2,070.00 Patient Support Laboratorio Clinico Toledo $1,650.00 Patient Support Laboratorio Clinico Toledo $1,500.00 Patient Support Laboratorio Clinico Toledo $1,395.00 Patient Support Laboratorio Clinico Toledo $1,380.00 Patient Support Laboratorio Clinico Toledo $1,290.00 Patient Support Laboratorio Clinico Toledo $1,200.00 Patient Support Laboratorio Clinico Toledo $996.00 Patient Support Laboratorio Clinico Toledo $825.00 Patient Support Laboratorio Clinico Toledo $804.00 Patient Support Laboratorio Clinico Toledo $4,455.00 Patient Support Laboratorio Clinico Toledo $945.00 Patient Support Laboratorio Clinico Toledo $690.00 Patient Support Laboratorio Clinico Toledo $1,530.00 Patient Support Laboratorio Clinico Toledo $1,335.00 Patient Support Laboratorio Clinico Toledo $1,065.00 Patient Support Laboratorio Clinico Toledo $975.00 Patient Support Laboratorio Clinico Toledo $2,250.00 Patient Support Laboratorio Clinico Toledo $2,250.00 Patient Support Laboratorio Clinico Toledo $825.00 Patient Support Laboratorio Clinico Toledo $720.00 Patient Support Laboratorio Clinico Toledo $510.00 Patient Support Laboratorio Clinico Toledo $1,500.00 Patient Support Laboratorio Clinico Toledo $1,500.00 Patient Support Laboratorio Clinico Toledo $1,500.00 Patient Support Laboratorio Clinico Toledo $1,365.00 Patient Support Laboratorio Clinico Toledo $1,185.00 Patient Support Laboratorio Clinico Toledo $1,125.00 Patient Support Laboratorio Clinico Toledo $1,110.00 Patient Support Laboratorio Clinico Toledo $1,095.00 Patient Support Laboratorio Clinico Toledo $855.00 Patient Support Laboratorio Clinico Toledo $765.00 Patient Support Laboratorio Clinico Toledo $750.00 Patient Support Laboratorio Clinico Toledo $525.00 Patient Support Laboratorio Clinico Toledo $1,230.00 Patient Support Laboratorio Clinico Toledo $1,185.00 Patient Support Laboratorio Clinico Toledo $1,110.00 Patient Support Laboratorio Clinico Toledo $960.00 Patient Support Laboratorio Clinico Toledo $300.00 Patient Support Laboratorio Clinico Toledo $1,500.00 Patient Support Laboratorio Clinico Toledo $1,230.00 Patient Support Laboratorio Clinico Toledo $720.00 Patient Support Laboratorio Clinico Toledo $570.00 Patient Support Laboratorio Clinico Toledo $1,035.00 Patient Support Laboratorio Clinico Toledo $990.00 Patient Support Laboratorio Clinico Toledo $810.00 Patient Support Laboratorio Clinico Toledo $705.00 Patient Support Laboratorio Clinico Toledo $705.00 Patient Support Laboratorio Clinico Toledo $1,095.00 Patient Support Laboratorio Clinico Toledo $750.00 Patient Support Laboratorio Clinico Toledo $675.00 Patient Support Laboratorio Clinico Toledo $255.00 Patient Support Laboratorio Clinico Toledo $1,470.00 Patient Support Laboratorio Clinico Toledo $1,275.00 Patient Support Laboratorio Clinico Toledo $1,230.00 Patient Support Laboratorio Clinico Toledo $1,095.00 Patient Support Laboratorio Clinico Toledo $900.00 Patient Support Laboratorio Clinico Toledo $585.00 Patient Support Laboratorio Clinico Toledo $1,890.00 Patient Support Laboratorio Clinico Toledo $1,380.00 Patient Support Laboratorio Clinico Toledo $1,185.00 Patient Support Laboratorio Clinico Toledo $975.00 Patient Support Laboratorio Clinico Toledo $2,190.00 Patient Support Lake County Haven $5,000.00 Corporate Sponsorship Large Urology Group 66,400.00 Corporate Sponsorship Practice Association Latinos Salud, Inc. $7,500.00 Charitable Donations Legacy Counseling Center $7,500.00 Charitable Donations Leukemia and Lymphoma $2,500.00 Educational Grants Society, The Leukemia Research $2,500.00 Charitable Donations Foundation Life Sciences Foundation $30,000.00 Charitable Donations Life Sciences Foundation $30,000.00 Charitable Donations Life Sciences Foundation $30,000.00 Charitable Donations Linking Leaders, LLC $20,000.00 Corporate Sponsorship Liver Institute and $50,000.00 Educational Grants Foundation for Education and Research Living Beyond Breast Cancer $10,000.00 Corporate Sponsorship Living Beyond Breast Cancer $5,000.00 Corporate Sponsorship Living Beyond Breast Cancer $5,000.00 Corporate Sponsorship Loma Linda University $1,200.00 Fellowships and School of Medicine Scholarships Malecare $12,000.00 Patient Support Marsha Rivkin Center for $2,500.00 Educational Grants Ovarian Cancer Research Massachusetts General $25,000.00 Fellowships and Hospital Scholarships Massachusetts Institute of $2,220.00 Charitable Donations Technology Massachusetts Institute of $2,220.00 Charitable Donations Technology Massachusetts Institute of $5,000.00 Educational Grants Technology Massachusetts Prostate $5,000.00 Educational Grants Cancer Coalition, Inc. May We Help $3,000.00 Corporate Sponsorship May We Help $2,500.00 Corporate Sponsorship May We Help $2,500.00 Corporate Sponsorship Mayo Clinic $10,000.00 Educational Grants Medical College of $10,000.00 Educational Grants Wisconsin Medical College of $15,000.00 Educational Grants Wisconsin Medical Learning Institute $90,000.00 Educational Grants Medical Learning Institute $(90,000.00) Educational Grants Medical Learning Institute $75,000.00 Educational Grants Medicinal and Bioorganic $5,000.00 Educational Grants Chemistry Foundation, The Medscape, LLC $250,000.00 Educational Grants Medscape, LLC $250,000.00 Educational Grants Medscape, LLC $100,000.00 Educational Grants Medscape, LLC $75,000.00 Educational Grants Medscape, LLC $740,500.00 Educational Grants Medscape, LLC $471,000.00 Educational Grants Medscape, LLC $37,000.00 Educational Grants Medscape, LLC $155,000.00 Educational Grants Medscape, LLC $150,000.00 Educational Grants Memorial Hermann Foundation $40,000.00 Fellowships and Scholarships Memphis Business Group on $4,820.00 Corporate Sponsorship Health Mercer County Joint $2,646.00 Patient Support Township Community Hospital dba Mercer Health Methodist Hospital, The $25,000.00 Corporate Sponsorship Michael J. Fox Foundation $32,000.00 Educational Grants Michael J. Fox Foundation $25,000.00 Corporate Sponsorship Michael J. Fox Foundation $25,000.00 Corporate Sponsorship Michigan Council of Nurse $1,200.00 Educational Grants Practitioners Michigan Institute of $5,000.00 Corporate Sponsorship Urology Mid Atlantic Business Group $3,000.00 Corporate Sponsorship Health Mid-America Coalition on $1,000.00 Corporate Sponsorship Health Care Miles for Cystic Fibrosis $5,000.00 Corporate Sponsorship Mississippi Kidney $2,000.00 Educational Grants Foundation Missouri Hepatitis C $20,000.00 Charitable Donations Alliance Missouri Hepatitis C $10,000.00 Patient Support Alliance Montana Association of $2,000.00 Corporate Sponsorship Health Care Purchaser Mount Sinai School of $40,000.00 Fellowships and Medicine Scholarships Mount Sinai School of $240,000.00 Educational Grants Medicine Mount Sinai School of $10,000.00 Charitable Donations Medicine Mount Sinai School of $20,000.00 Educational Grants Medicine Mount Sinai School of $8,000.00 Educational Grants Medicine Mount Sinai School of $10,000.00 Educational Grants Medicine Movement Disorder Society, $12,000.00 Educational Grants The Movement Disorder Society, $234,000.00 Corporate Sponsorship The National Academy of $40,000.00 Educational Grants Sciences National Academy of $10,000.00 Charitable Donations Sciences National Academy of $85,000.00 Corporate Sponsorship Sciences National AIDS Treatment $300,000.00 Charitable Donations Advocacy Project National Alliance of State $100,000.00 Charitable Donations and Territorial AIDS Directors National Association for $100,000.00 Educational Grants Continuing Education National Association of $11,500.00 Corporate Sponsorship Chain Drug Stores, Inc. National Association of $25,000.00 Educational Grants Managed Care Physicians National Association of $35,000.00 Educational Grants Managed Care Physicians National Association of $10,000.00 Charitable Donations School Nurses, Inc. National Commission on $5,000.00 Educational Grants Correctional Health Care National Committee for $10,000.00 Corporate Sponsorship Quality Assurance National Committee for $150,000.00 Educational Grants Quality Assurance National Committee for $10,000.00 Corporate Sponsorship Quality Assurance National Committee for $125,000.00 Corporate Sponsorship Quality Assurance National Comprehensive $10,000.00 Educational Grants Cancer Network National Comprehensive $(1,492.41) Educational Grants Cancer Network National Comprehensive $10,000.00 Educational Grants Cancer Network National Comprehensive $25,000.00 Charitable Donations Cancer Network National Comprehensive $10,000.00 Corporate Sponsorship Cancer Network National Foundation for the $500,000.00 Corporate Sponsorship Centers for Disease Control and Prevention National Foundation for the $37,500.00 Corporate Sponsorship Centers for Disease Control and Prevention National Hispanic Council $10,000.00 Charitable Donations on Aging National Jewish Health $151,840.00 Educational Grants National Jewish Health $75,000.00 Educational Grants National Kidney Foundation $500.00 Corporate Sponsorship of Louisiana, Inc. National Kidney Foundation $3,000.00 Patient Support of Northeast New York National Kidney Foundation, $5,000.00 Corporate Sponsorship Inc. National Kidney Foundation, $20,000.00 Educational Grants Inc. National Kidney Foundation, $333,333.33 Corporate Sponsorship Inc. National Medical $5,000.00 Corporate Sponsorship Association National Multiple Sclerosis $10,000.00 Corporate Sponsorship Society National Pancreas $6,000.00 Corporate Sponsorship Foundation National Pancreas $200,000.00 Educational Grants Foundation National Pancreas $50,000.00 Charitable Donations Foundation National Pancreas $65,000.00 Educational Grants Foundation National Parkinson $25,000.00 Corporate Sponsorship Foundation, Inc. National Parkinson $40,000.00 Educational Grants Foundation, Inc. National Parkinson $25,000.00 Educational Grants Foundation, Inc. National Psoriasis $125,000.00 Corporate Sponsorship Foundation National Psoriasis $20,000.00 Educational Grants Foundation National Psoriasis $500,000.00 Corporate Sponsorship Foundation National Psoriasis $20,000.00 Educational Grants Foundation National Psoriasis $2,500.00 Corporate Sponsorship Foundation National Psoriasis $50,000.00 Patient Support Foundation National Psoriasis $15,000.00 Corporate Sponsorship Foundation National Psoriasis $1,000.00 Corporate Sponsorship Foundation National Psoriasis $125,000.00 Corporate Sponsorship Foundation National Society for $50,000.00 Corporate Sponsorship Cutaneous Medicine National Society for $100,000.00 Corporate Sponsorship Cutaneous Medicine National Society for $100,000.00 Corporate Sponsorship Cutaneous Medicine NephCure Foundation $5,000.00 Patient Support Neuro Community Foundation $2,000.00 Educational Grants New England Baptist $5,000.00 Corporate Sponsorship Hospital New Jersey Association for $2,000.00 Educational Grants Biomedical Research New York Academy of $2,000.00 Educational Grants Sciences New York Academy of $5,000.00 Educational Grants Sciences New York Academy of $2,500.00 Educational Grants Sciences New York Medical College, $2,000.00 Educational Grants office of Continuing Medical Education New York State Rheumatology $17,500.00 Corporate Sponsorship Society New York University School $5,000.00 Educational Grants of Medicine New York University School $40,000.00 Fellowships and of Medicine Scholarships New York University School $5,000.00 Educational Grants of Medicine New York University School $5,800.00 Educational Grants of Medicine New York University School $55,000.00 Educational Grants of Medicine New York University School $15,000.00 Educational Grants of Medicine New York University School $5,000.00 Educational Grants of Medicine Nicole Jarvis MD Parkinsons $500.00 Corporate Sponsorship Research Foundation NL Communications, Inc. $35,000.00 Educational Grants NL Communications, Inc. $25,000.00 Educational Grants NL Communications, Inc. $50,000.00 Educational Grants No AIDS Task force $2,000.00 Educational Grants North American Center for $252,250.00 Educational Grants Continuing Medical Education North American Center for $45,000.00 Educational Grants Continuing Medical Education North American Center for $124,975.00 Educational Grants Continuing Medical Education North American Center for $318,000.00 Educational Grants Continuing Medical Education North American Center for $95,000.00 Educational Grants Continuing Medical Education North American Center for $475,000.00 Educational Grants Continuing Medical Education North American Center for $200,000.00 Educational Grants Continuing Medical Education North American Center for $250,000.00 Educational Grants Continuing Medical Education North American Center for $99,500.00 Educational Grants Continuing Medical Education North American Center for $225,000.00 Educational Grants Continuing Medical Education North American Society for $20,000.00 Educational Grants Pediatric Gastroenterology, Hepatology, and Nutrition North Carolina Rheumatology $20,000.00 Corporate Sponsorship Association North Dakota Academy of $1,500.00 Educational Grants Physician Assistants Northeast Business Group on $8,000.00 Corporate Sponsorship Health Northwest Arthritis and $150,000.00 Educational Grants Osteoporosis Institute Northwest Kidney Centers $2,500.00 Corporate Sponsorship Northwest Kidney Centers $2,500.00 Corporate Sponsorship Northwest Urological $5,000.00 Corporate Sponsorship Society Northwestern Lake forest $984.00 Charitable Donations Hospital Northwestern University $2,220.00 Charitable Donations Northwestern University $2,220.00 Charitable Donations Northwestern University $40,000.00 Fellowships and Scholarships Northwestern University $5,000.00 Educational Grants Northwestern University $40,000.00 Fellowships and Scholarships Northwestern University $50,000.00 Fellowships and Scholarships Northwestern University $5,000.00 Educational Grants Northwestern University $7,500.00 Educational Grants Ohio Association of $10,000.00 Corporate Sponsorship Rheumatology Ohio Gastroenterology $5,000.00 Corporate Sponsorship Society Oregon Health & Science $800.00 Educational Grants University Osteoarthritis Research $10,000.00 Educational Grants Society International Pacific Dermatologic $10,000.00 Corporate Sponsorship Association PACK Health, LLC $135,875.00 Educational Grants Pancreas Club, The $10,000.00 Educational Grants Pancreatic Cancer Action $2,500.00 Corporate Sponsorship Network, Inc. Pancreatic Cancer Action $2,500.00 Corporate Sponsorship Network, Inc. Pancreatic Cancer Action $5,000.00 Corporate Sponsorship Network, Inc. Pancreatic Cancer Action $5,000.00 Corporate Sponsorship Network, Inc. Pancreatic Cancer Action $5,000.00 Corporate Sponsorship Network, Inc. Pancreatic Cancer Action $5,000.00 Corporate Sponsorship Network, Inc. Pancreatic Cancer Action $5,000.00 Corporate Sponsorship Network, Inc. Pancreatic Cancer Action $147,600.00 Corporate Sponsorship Network, Inc. Pancreatic Cancer Action $5,000.00 Corporate Sponsorship Network, Inc. Pancreatic Cancer Action $5,000.00 Corporate Sponsorship Network, Inc. Pancreatic Cancer Action $5,000.00 Corporate Sponsorship Network, Inc. Parkinson Association of $7,500.00 Educational Grants the Rockies Parkinson Foundation of the $5,000.00 Educational Grants National Capital Area Parkinson Research $10,000.00 Educational Grants Foundation Parkinson Research $5,000.00 Educational Grants Foundation Parkinson Research $5,000.00 Educational Grants Foundation Parkinson Study Group $8,000.00 Educational Grants Parkinson Support Group of $2,000.00 Educational Grants Upstate NY dba NPF Greater Rochester Parkinson's Action Network $35,000.00 Corporate Sponsorship Foundation Parkinson's Action Network $15,000.00 Corporate Sponsorship Foundation Parkinson's Action Network $25,000.00 Corporate Sponsorship Foundation Parkinson's Disease $20,000.00 Educational Grants Foundation Parkinson's Disease $50,000.00 Educational Grants Foundation Parkinsons Resources of $5,000.00 Educational Grants Oregon Parkinsons Resources of $5,000.00 Educational Grants Oregon Parkinson's Unity Walk $150,000.00 Corporate Sponsorship Parkinsons Voice Project $1,000.00 Corporate Sponsorship Partners HealthCare System $40,000.00 Educational Grants Partnership for a Drug Free $100,000.00 Charitable Donations America Patient Empowerment Network $20,000.00 Educational Grants Patient Empowerment Network $15,000.00 Educational Grants Pediatric IBD Foundation $15,000.00 Corporate Sponsorship Peer Health Communications, $50,000.00 Educational Grants LLC Pennsylvania Prostate $5,000.00 Educational Grants Cancer Coalition Pennsylvania Society of $11,400.00 Corporate Sponsorship Gastroenterology Pennsylvania State $75,000.00 Educational Grants University Pennsylvania State $456,750.00 Educational Grants University Pennsylvania State $5,000.00 Educational Grants University Pharmaceutical Care $50,000.00 Corporate Sponsorship Management Association Pharmaceutical Care $75,000.00 Corporate Sponsorship Management Association Pharmaceutical Research and $200,000.00 Charitable Donations Manufacturers of America Foundation Pharmacy Quality Alliance $15,000.00 Educational Grants Pharmacy Quality Alliance $12,500.00 Educational Grants Pharmacy Times office of $90,000.00 Educational Grants Continuing Professional Education Pharmacy Times office of $25,000.00 Educational Grants Continuing Professional Education Physicians Education $45,000.00 Educational Grants Resource Pittsburgh Magazine $3,500.00 Corporate Sponsorship Postgraduate Institute for $245,035.00 Educational Grants Medicine Potomac Center for Medical $(550.00) Educational Grants Education President and Fellows of $25,000.00 Corporate Sponsorship Harvard College Prevent Cancer Foundation $10,000.00 Corporate Sponsorship Primary Care Network, Inc. $142,375.00 Educational Grants Prime Education, Inc. $100,110.00 Educational Grants Prime Education, Inc. $148,780.00 Educational Grants Prime Education, Inc. $482,600.00 Educational Grants Prime Education, Inc. $138,850.00 Educational Grants Prime Education, Inc. $(769.00) Educational Grants Prime Education, Inc. $315,393.00 Educational Grants Prime Oncology, Inc. $10,000.00 Educational Grants Prime Oncology, Inc. $35,000.00 Educational Grants Prime Oncology, Inc. $30,000.00 Educational Grants Pri-Med Institute, LLC $77,500.00 Educational Grants Princeton University, $50,000.00 Fellowships and Trustees Scholarships Project Inform, Inc. $75,000.00 Educational Grants Project Inform, Inc. $75,000.00 Charitable Donations Projects In Knowledge, Inc. $125,000.00 Educational Grants Projects In Knowledge, Inc. $150,000.00 Educational Grants Prostate Cancer Foundation $5,000.00 Corporate Sponsorship Rodin Group Prostate Cancer Research $25,000.00 Educational Grants Institute Prostate Cancer Research $10,000.00 Corporate Sponsorship Institute Prostate Conditions $2,500.00 Corporate Sponsorship Education Council Prostate Health Education $15,000.00 Patient Support Network Prostate Health Education $15,000.00 Educational Grants Network Prostate Health $5,000.00 Corporate Sponsorship International Puerto Rico Association of $10,000.00 Educational Grants Gastroenterology Puerto Rico Association of $10,000.00 Educational Grants Gastroenterology Purdue University $83,890.00 Educational Grants Purdue University $400,000.00 Educational Grants Purdue University $450,000.00 Educational Grants Rector & Visitors of the $25,000.00 Educational Grants University of Virginia Regents of the University $40,000.00 Fellowships and of California, The Scholarships Regents of the University $5,000.00 Educational Grants of California, The Regents of the University $12,000.00 Corporate Sponsorship of California, The Regents of the University $5,000.00 Educational Grants of California, The Regents of the University $8,000.00 Educational Grants of California, The Regents of the University $10,000.00 Educational Grants of California, The Regents of the University $10,000.00 Corporate Sponsorship of Michigan Research America $25,000.00 Corporate Sponsorship Rheumatology Alliance of $25,000.00 Corporate Sponsorship Louisiana Rheumatology Nurses Society $50,000.00 Educational Grants Rheumatology Nurses Society $74,225.00 Educational Grants Rheumatology Nurses Society $50,000.00 Educational Grants Rheumatology Nurses Society $7,500.00 Corporate Sponsorship Richmond University Medical $1,100.00 Educational Grants Center Robert Michael Educational $70,000.00 Educational Grants Institute, LLC Robert Michael Educational $150,000.00 Educational Grants Institute, LLC Rush University Medical $40,000.00 Educational Grants Center Rush University Medical $5,000.00 Patient Support Center Rush University Medical $10,000.00 Educational Grants Center Rutgers, The State $125,000.00 Educational Grants University of New Jersey Rutgers, The State $60,000.00 Educational Grants University of New Jersey Rutgers, The State $75,000.00 Educational Grants University of New Jersey Rutgers, The State $25,000.00 Educational Grants University of New Jersey Sacramento Valley Society $500.00 Corporate Sponsorship of Health System Pharmacists Safety Pharmacology Society $2,500.00 Educational Grants Saint Anthony Hospital $3,410.00 Patient Support Foundation Saint Louis University $5,000.00 Educational Grants San Francisco AIDS $25,000.00 Corporate Sponsorship Foundation San Juan Bautista Medical $40,000.00 Fellowships and Scholarships Schneps Publications Inc. $695.00 Corporate Sponsorship DBA Queens Courier Scripps Health $150,000.00 Educational Grants Sexual Medicine Society of $55,000.00 Corporate Sponsorship North America, Inc. Sexual Medicine Society of $225,000.00 Corporate Sponsorship North America, Inc. Shanti Project, Inc. $20,000.00 Educational Grants Skin Disease Education $30,000.00 Corporate Sponsorship Foundation Skin Disease Education $80,000.00 Corporate Sponsorship Foundation Skin Disease Education $42,750.00 Corporate Sponsorship Foundation Skin Disease Education $46,250.00 Corporate Sponsorship Foundation Smart Ride, The $20,000.00 Corporate Sponsorship Smith Wholesale Drug $9,000.00 Corporate Sponsorship Company Sociedad Pr Endocrinologia $(7,500.00) Educational Grants Y Diabetologia Sociedad Puertorriquena $1,000.00 Educational Grants Pediatria Society for Neuroscience $2,500.00 Educational Grants Society for Neuroscience, $1,000.00 Educational Grants Chicago Chapter Society for Surgery of The $7,000.00 Corporate Sponsorship Alimentary Tract Society of Dermatology $20,000.00 Corporate Sponsorship Physician Assistants Society of Toxicologic $15,000.00 Corporate Sponsorship Pathology Society of Toxicology $5,000.00 Corporate Sponsorship South Carolina Alliance of $5,000.00 Corporate Sponsorship Health Plans Southern California Society $5,500.00 Corporate Sponsorship of Gastroenterologists Southern California Society $10,000.00 Educational Grants of Gastroenterology Southern Illinois $3,000.00 Fellowships and University School of Scholarships Medicine Spondylitis Association of $40,000.00 Patient Support America Spondylitis Association of $19,084.50 Educational Grants America St. Francis Hospital and $20,000.00 Educational Grants Medical Center State of Maryland $(1,308.80) Educational Grants State of Maryland $45,000.00 Fellowships and Scholarships State University of Iowa $1,500.00 Educational Grants States United for $5,000.00 Charitable Donations Biomedical Research Super Jake Foundation, The $25,000.00 Corporate Sponsorship Teratology Society $1,500.00 Educational Grants Test positive Aware Network $2,500.00 Patient Support Test positive Aware Network $30,000.00 Corporate Sponsorship Texas Association of Health $1,500.00 Corporate Sponsorship Plans Texas Urological Society $6,000.00 Corporate Sponsorship The Endocrine Society $25,000.00 Educational Grants The Hitchcock Foundation $25,000.00 Educational Grants The Reginald and Dionne $5,000.00 Patient Support Smith Foundation, Inc. The Reginald and Dionne $5,000.00 Patient Support Smith Foundation, Inc. Tides Center $10,000.00 Educational Grants Tides Center $50,000.00 Educational Grants Tides Center $50,000.00 Educational Grants Trinitas Regional Medical $1,800.00 Educational Grants Center Triple Step Toward the Cure $5,000.00 Corporate Sponsorship Trustees of the University $69,742.00 Educational Grants of Pennsylvania Trustees of the University $50,000.00 Educational Grants of Pennsylvania Tufts Medical Center $(3,825.00) Educational Grants Tufts Medical Center $4,000.00 Fellowships and Scholarships Tufts University $8,000.00 Educational Grants Twine Clinical Consulting $158,000.00 Educational Grants LLC UC Regents Maxillofacial $20,000.00 Educational Grants Prosthetics Clinic UC Regents Maxillofacial $50,000.00 Fellowships and Prosthetics Clinic Scholarships UC Regents Maxillofacial $50,000.00 Fellowships and Prosthetics Clinic Scholarships UC Regents Maxillofacial $5,000.00 Educational Grants Prosthetics Clinic UC Regents Maxillofacial $20,000.00 Educational Grants Prosthetics Clinic Ultimate Medical Academy $90,000.00 Educational Grants Med Learning Group, LLC Ultimate Medical Academy $(125,000.00) Educational Grants Med Learning Group, LLC United States Adult Cystic $6,000.00 Educational Grants Fibrosis Association, Inc. United Way of Central $5,000.00 Corporate Sponsorship Massachusetts Universidad De Puerto Rico $40,000.00 Fellowships and Scholarships Universidad De Puerto Rico $6,325.00 Educational Grants University Health Services $25,000.00 Educational Grants at Stony Point, Inc. University Health Services $150,111.40 Educational Grants at Stony Point, Inc. University Hospital of $10,000.00 Educational Grants Brooklyn University of Alabama at $40,000.00 Fellowships and Birmingham Scholarships University of California $5,000.00 Educational Grants University of California-- $15,000.00 Corporate Sponsorship San Francisco University of California-- $10,000.00 Educational Grants San Francisco University of California-- $10,000.00 Educational Grants San Francisco University of California $30,000.00 Charitable Donations Berkeley University of California $40,000.00 Fellowships and Irvine Scholarships University of Chicago $60,000.00 Educational Grants University of Chicago $28,961.64 Fellowships and Scholarships University of Chicago $5,000.00 Educational Grants University of Chicago $204,525.00 Educational Grants University of Chicago $5,000.00 Educational Grants University of Chicago $150,000.00 Educational Grants University of Chicago $75,000.00 Educational Grants University of Chicago $100,000.00 Educational Grants University of Chicago $25,000.00 Charitable Donations Cancer Research Foundation University of Cincinnati $100,000.00 Corporate Sponsorship University of Cincinnati $75,000.00 Educational Grants University of Cincinnati $100,000.00 Educational Grants University of Cincinnati $75,000.00 Educational Grants University of Cincinnati $100,000.00 Educational Grants University of Cincinnati $50,000.00 Educational Grants University of Cincinnati $2,542,080.00 Educational Grants University of Cincinnati $50,000.00 Corporate Sponsorship University of Cincinnati $8,000.00 Educational Grants University of Cincinnati $10,000.00 Educational Grants University of Connecticut $12,000.00 Fellowships and Scholarships University of Florida $142,709.00 Educational Grants University of Florida $65,000.00 Educational Grants University of Florida $50,000.00 Fellowships and Foundation Scholarships University of Illinois $2,220.00 Charitable Donations Foundation University of Illinois $2,220.00 Charitable Donations Foundation University of Louisville $2,220.00 Charitable Donations Foundation University of Louisville $150,000.00 Educational Grants Research Foundation University of Louisville $35,000.00 Educational Grants Research Foundation University of Louisville $25,000.00 Educational Grants Research Foundation University of Maryland $10,000.00 Educational Grants Baltimore Foundation University of Massachusetts $10,000.00 Charitable Donations Medical School University of Miami $112,000.00 Educational Grants University of Michigan $(254.37) Educational Grants University of Minnesota $2,220.00 Charitable Donations University of Minnesota, $5,000.00 Educational Grants Regents University of Minnesota, $(160.43) Corporate Sponsorship Regents University of Mississippi $10,000.00 Charitable Donations Foundation University of Nebraska $5,000.00 Educational Grants Medical Center University of Nebraska $2,500.00 Educational Grants Medical Center University of Nebraska $15,000.00 Educational Grants Medical Center University of New Mexico $142,150.00 Educational Grants Health Sciences Center, Department of Pediatrics Neonatology Division University of North $50,000.00 Fellowships and Carolina at Chapel Hill Scholarships University of North $5,000.00 Educational Grants Carolina at Chapel Hill University of Notre Dame $1,000.00 Educational Grants University of Pittsburgh $1,500.00 Fellowships and Scholarships University of Pittsburgh $10,000.00 Educational Grants University of Pittsburgh $20,000.00 Educational Grants University of Rochester $40,000.00 Fellowships and Scholarships University of Rochester $4,225.00 Educational Grants University of Rochester $(1,207.00) Educational Grants University of South Florida $150,000.00 Educational Grants Health Professions Conferencing Corporation University of Southern $180,000.00 Educational Grants California University of Southern $1,500.00 Educational Grants California University of Southern $30,000.00 Educational Grants California University of Texas Health $25,000.00 Educational Grants Science Center at San Antonio University of Texas Health $10,000.00 Educational Grants Science Center at San Antonio University of Texas Health $10,000.00 Educational Grants Science Center at San Antonio University of Texas M.D. $20,000.00 Educational Grants Anderson Cancer Center University of Texas M.D. $10,000.00 Educational Grants Anderson Cancer Center University of Utah $40,000.00 Fellowships and Scholarships University of Utah $2,200.00 Educational Grants University of Washington $50,000.00 Fellowships and Scholarships University of Washington $40,000.00 Fellowships and Scholarships University of Wisconsin $2,220.00 Charitable Donations Medical Foundation University of Wisconsin $2,000.00 Educational Grants Systems University of Wisconsin $(500.00) Corporate Sponsorship Systems University of Wisconsin- $(1,857.88) Educational Grants Madison University of Wisconsin- $2,000.00 Educational Grants Madison Urological Association of $2,500.00 Educational Grants Pennsylvania Urology Center of Colorado $7,500.00 Corporate Sponsorship Foundation Us Too International $15,000.00 Educational Grants Us Too International $5,000.00 Educational Grants Us Too International $25,000.00 Corporate Sponsorship Us Too International $5,000.00 Corporate Sponsorship Us Too International $1,000.00 Corporate Sponsorship Valley Children's Hospital $2,500.00 Patient Support Foundation Venice Family Clinic $10,000.00 Charitable Donations Veritas Institute for $(50,000.00) Educational Grants Medical Education, Inc. Vindico Medical Education $337,509.00 Educational Grants Virginia Commonwealth $2,100.00 Patient Support University, School of Medicine Wake forest University $40,000.00 Fellowships and Scholarships Washington Hospital Center $10,000.00 Educational Grants Corporation Washington Rheumatology $30,000.00 Corporate Sponsorship Alliance Washington State Urology $5,000.00 Corporate Sponsorship Society Washington University in $2,220.00 Charitable Donations St. Louis Wayne State University $2,220.00 Charitable Donations We Care in Inflammatory $50,000.00 Charitable Donations Bowel Disease West Penn Allegheny Health $6,000.00 Educational Grants System, Inc. West Penn Allegheny Health $(5,905.00) Fellowships and System, Inc. Scholarships West Virginia University $2,220.00 Charitable Donations Western States Pharmacy $7,500.00 Corporate Sponsorship Conference for Pharmacy Residents Fellowships and Preceptors Why Me, Inc. $2,500.00 Charitable Donations WINGS Program Inc. $25,000.00 Charitable Donations Wisconsin Dairyland Chapter $2,000.00 Corporate Sponsorship of Healthcare Information and Management Systems Society Wisconsin Rheumatology $10,000.00 Corporate Sponsorship Association Wishes And Dreams for $1,000.00 Corporate Sponsorship Cystic Fibrosis Worcester Regional Research $2,500.00 Corporate Sponsorship Bureau, Inc. World Endometriosis $18,000.00 Corporate Sponsorship Research Foundation World Endometriosis Society $150,000.00 Corporate Sponsorship World Endometriosis Society $150,000.00 Corporate Sponsorship World Health $50,000.00 Educational Grants Communications, Ltd. World Parkinson Coalition $15,000.00 Educational Grants Inc. World Senior Games $5,250.00 Corporate Sponsorship Yale University School of $5,000.00 Educational Grants Medicine Yale University School of $(10,000.00) Educational Grants Medicine Yale University School of $10,000.00 Educational Grants Medicine Young Survival Coalition $5,000.00 Corporate Sponsorship Zero, The Project to End $7,500.00 Corporate Sponsorship Prostate Cancer Zero, The Project to End $210,800.00 Corporate Sponsorship Prostate Cancer Zero, The Project to End $15,000.00 Corporate Sponsorship Prostate Cancer Zero, The Project to End $2,500.00 Corporate Sponsorship Prostate Cancer ------------------------------------------------------------------------ Grants Donations Report--2015 (Parentheses represent refunds of previously disclosed payments) Updated as of 4/30/2018 ------------------------------------------------------------------------ Recipient Payment Amount Purpose ------------------------------------------------------------------------ A Runner's Love $5,000.00 Corporate Sponsorship Academia Medica Del Sur $12,000.00 Educational Grants Academia Medica Del Sur $8,000.00 Educational Grants Academia Medica Del Sur $15,000.00 Educational Grants Academia Medica Del Sur $15,000.00 Educational Grants Academia Medica Del Sur $10,000.00 Educational Grants Academia Medica Del Sur $10,000.00 Educational Grants Academia Medica Del Sur $9,000.00 Educational Grants Academia Medica Del Sur $12,000.00 Educational Grants Academia Medica Del Sur $14,000.00 Educational Grants Academia Medica Del Sur $10,000.00 Educational Grants Academia Medica Del Sur $10,000.00 Educational Grants Academia Medica Del Sur $15,000.00 Educational Grants Academia Medica Del Sur $5,000.00 Educational Grants Academia Medica Del Sur $15,000.00 Educational Grants Academia Medica Del Sur $10,000.00 Educational Grants Academia Medica Del Sur $5,000.00 Educational Grants Academia Medica Del Sur $7,500.00 Educational Grants Academia Medica Del Sur $12,000.00 Educational Grants Academia Medica Del Sur $10,000.00 Educational Grants Academia Medica Del Sur $7,500.00 Educational Grants Academia Medica Del Sur $10,000.00 Educational Grants Academia Medica Del Sur $10,000.00 Educational Grants Academia Medica Del Sur $15,000.00 Educational Grants Academia Medica Del Sur $10,000.00 Educational Grants Academia Medica Del Sur $12,000.00 Educational Grants Academia Medica Del Sur $15,000.00 Educational Grants Academia Medica Del Sur $15,000.00 Educational Grants Academia Medica Del Sur $10,000.00 Educational Grants Academia Medica Del Sur $10,000.00 Educational Grants Academia Medica Del Sur $15,000.00 Educational Grants Academia Medica Del Sur $10,000.00 Educational Grants Academia Medica Del Sur $15,000.00 Educational Grants Academia Medica Del Sur $10,000.00 Educational Grants Academia Medica Del Sur $10,000.00 Educational Grants Academia Medica Del Sur $9,000.00 Educational Grants Academia Medica Del Sur $10,000.00 Educational Grants Academia Medica Del Sur $15,000.00 Educational Grants Academia Puertorriquena De $8,500.00 Corporate Sponsorship Neurologia Academy of Managed Care $25,000.00 Corporate Sponsorship Pharmacy Academy of Managed Care $75,000.00 Corporate Sponsorship Pharmacy Academy of Managed Care $30,000.00 Corporate Sponsorship Pharmacy Academy of Managed Care $25,000.00 Corporate Sponsorship Pharmacy Academy of Managed Care $40,000.00 Corporate Sponsorship Pharmacy Advances in Cosmetic and $50,000.00 Corporate Sponsorship Medical Dermatology Inc. Advances in Cosmetic and $50,000.00 Corporate Sponsorship Medical Dermatology Inc. Advances in Cosmetic and $100,000.00 Corporate Sponsorship Medical Dermatology Inc. Adventist Hlth System-- $15,000.00 Corporate Sponsorship Sunbelt Inc. Advocate Health & Hospitals $2,500.00 Educational Grants Corporation Aids Drug Assistance $5,000.00 Educational Grants Programs Advocacy Asoc AIDS Action Committee $5,000.00 Corporate Sponsorship AIDS Foundation of Chicago $125,000.00 Charitable Donation AIDS Foundation of Chicago $25,000.00 Corporate Sponsorship AIDS Foundation of Chicago $10,000.00 Corporate Sponsorship Alabama Dermatology Society $35,000.00 Corporate Sponsorship Albany Medical Center $10,000.00 Corporate Sponsorship Albany Medical Center $5,000.00 Educational Grants Albert Einstein Colg of $10,000.00 Educational Grants Medicine Div of Dermatology Attending Asoc Albert Einstein Colg of $85,000.00 Educational Grants Medicine of Yeshiva Univ Albert Einstein Med Ctr. $2,500.00 Educational Grants Alliance for Clinical $25,000.00 Educational Grants Trials in Oncology Foundation Alliance for Safe Biologic $100,000.00 Corporate Sponsorship Medicines Alliance Foundation for $50,000.00 Educational Grants Continuing Education In The Health Professions American Academy of $75,000.00 Educational Grants Continuing Medical Education American Academy of ($37,982.00) Educational Grants Dermatology American Academy of $75,000.00 Educational Grants Dermatology American Academy of $40,000.00 Charitable Donation Dermatology American Academy of $35,000.00 Corporate Sponsorship Dermatology American Academy of $40,000.00 Educational Grants Dermatology American Academy of $20,000.00 Corporate Sponsorship Dermatology American Academy of $10,000.00 Corporate Sponsorship Dermatology American Academy of $35,000.00 Corporate Sponsorship Dermatology American Academy of $200,000.00 Corporate Sponsorship Dermatology American Academy of Family $38,000.00 Corporate Sponsorship Phys American Academy of Family $38,000.00 Corporate Sponsorship Phys American Academy of $38,500.00 Educational Grants Neurology Institute American Academy of $10,000.00 Educational Grants Neurology Institute American Assoc for Lab $20,000.00 Charitable Donation Animal Scnc Foundation American Assoc for The $50,000.00 Charitable Donation Study of Liver Diseases American Assoc for The $500,000.00 Charitable Donation Study of Liver Diseases American Assoc for The $130,000.00 Corporate Sponsorship Study of Liver Diseases American Assoc of Phys of $15,000.00 Corporate Sponsorship Indian Origin Arkansas American Assoc of Phys of $10,000.00 Corporate Sponsorship Indian Origin Arkansas American Assoc of Phys of $5,000.00 Corporate Sponsorship Indian Origin Arkansas American Association for $10,000.00 Educational Grants Cancer Research American Association for $35,000.00 Educational Grants Cancer Research American Association for $10,000.00 Educational Grants Cancer Research American Association for $5,000.00 Educational Grants Cancer Research American Association for $25,000.00 Educational Grants Cancer Research American Association for $10,000.00 Educational Grants Cancer Research American Association for $25,000.00 Educational Grants Cancer Research American Association for $10,000.00 Educational Grants Cancer Research American Association for $5,000.00 Educational Grants Laboratory Animal Science New England Branch American Association of $18,940.00 Educational Grants Clinical Endocrinologists American Association of $20,000.00 Educational Grants Clinical Endocrinologists American Association of $7,500.00 Educational Grants Clinical Endocrinologists American Association of $5,000.00 Educational Grants Clinical Endocrinologists American Association of $50,000.00 Corporate Sponsorship Pharmaceutical Scientists American Association of $3,150.00 Charitable Donation Pharmaceutical Scientists American Autoimmune Related $46,000.00 Corporate Sponsorship American Autoimmune Related $10,000.00 Corporate Sponsorship American Autoimmune Related $2,500.00 Corporate Sponsorship American Autoimmune Related $5,000.00 Corporate Sponsorship American Autoimmune Related $30,000.00 Corporate Sponsorship American Brain Tumor $10,000.00 Corporate Sponsorship Association American Cancer Society $10,000.00 Corporate Sponsorship American Cancer Society $2,000.00 Corporate Sponsorship Cancer Action Network American Cancer Society $7,000.00 Corporate Sponsorship Cancer Action Network American Cancer Society $5,000.00 Corporate Sponsorship Cancer Action Network American Cancer Society $2,500.00 Corporate Sponsorship Cancer Action Network American Cancer Society $1,000.00 Corporate Sponsorship Cancer Action Network American Cancer Society $10,000.00 Corporate Sponsorship Cancer Action Network American Cancer Society $2,500.00 Corporate Sponsorship Cancer Action Network American Cancer Society $1,000.00 Corporate Sponsorship Cancer Action Network American Chem Socty $2,500.00 Educational Grants American Chem Socty $1,000.00 Educational Grants American Chem Socty $2,500.00 Educational Grants American Chem Socty $2,500.00 Educational Grants American Colg of $355,000.00 Corporate Sponsorship Endocrinology American Colg of Lab Animal $50,000.00 Charitable Donation Medicine American Colg of $1,000.00 Corporate Sponsorship Obstetricians And Gynecologists District 1 American College of $1,000.00 Educational Grants Clinical Pharmacology American College of $90,000.00 Corporate Sponsorship Gastroenterology American College of $20,000.00 Corporate Sponsorship Gastroenterology American College of $25,000.00 Charitable Donation Gastroenterology American College of $100,000.00 Corporate Sponsorship Gastroenterology American College of $45,000.00 Corporate Sponsorship Gastroenterology American College of $90,000.00 Corporate Sponsorship Gastroenterology American College of $20,000.00 Corporate Sponsorship Gastroenterology American College of $3,000.00 Corporate Sponsorship Healthcare Executives Wisconsin Chapter American College of $2,000,000.00 Corporate Sponsorship Rheumatology American College of $5,000.00 Corporate Sponsorship Veterinary Pathologists American Drug Utilization $20,000.00 Corporate Sponsorship Review Society Adurs American Enterprise $10,000.00 Corporate Sponsorship Institute American $153,517.00 Educational Grants Gastroenterological Association Institute American $427,536.66 Educational Grants Gastroenterological Association Institute American $25,000.00 Corporate Sponsorship Gastroenterological Association Institute American $25,000.00 Corporate Sponsorship Gastroenterological Association Institute American $133,200.00 Corporate Sponsorship Gastroenterological Association Institute American $43,000.00 Corporate Sponsorship Gastroenterological Association Institute American $25,000.00 Corporate Sponsorship Gastroenterological Association Institute American Kidney Fund $5,000.00 Corporate Sponsorship American Legion $10,000.00 Corporate Sponsorship American Legion National $20,000.00 Corporate Sponsorship Headquarters American Liver Foundation $10,000.00 Corporate Sponsorship American Liver Foundation $4,500.00 Corporate Sponsorship American Liver Foundation $400,000.00 Corporate Sponsorship American Liver Foundation ($10,000.00) Corporate Sponsorship American Liver Foundation $25,000.00 Corporate Sponsorship American Liver Foundation $5,000.00 Corporate Sponsorship American Liver Foundation $25,000.00 Corporate Sponsorship American Liver Foundation $5,000.00 Corporate Sponsorship American Liver Foundation $35,000.00 Corporate Sponsorship American Medical Group $24,700.00 Corporate Sponsorship Association American Neurological $25,000.00 Educational Grants Association American Pancreatic $75,000.00 Educational Grants Association, Inc. American Pancreatic $25,000.00 Corporate Sponsorship Association, Inc. American Pancreatic $15,000.00 Charitable Donation Association, Inc. American Parkinson Disease $5,350.00 Corporate Sponsorship Association, Inc. American Parkinson Disease $2,000.00 Corporate Sponsorship Association, Inc. American Parkinson Disease $15,000.00 Educational Grants Association, Inc. American Parkinson Disease $2,500.00 Corporate Sponsorship Association, Inc. American Parkinson Disease $40,000.00 Educational Grants Association, Inc. American Parkinson Disease $3,000.00 Corporate Sponsorship Association, Inc. American Parkinson Disease $500.00 Corporate Sponsorship Association, Inc. American Parkinson Disease $500.00 Corporate Sponsorship Association, Inc. American Parkinson Disease $1,000.00 Corporate Sponsorship Association, Inc. American Parkinson Disease $5,000.00 Corporate Sponsorship Association, Inc. American Parkinson Disease $1,000.00 Corporate Sponsorship Association, Inc. American Parkinson Disease $500.00 Corporate Sponsorship Association, Inc. American Parkinson Disease $1,000.00 Corporate Sponsorship Association, Inc. American Parkinson Disease $500.00 Corporate Sponsorship Association, Inc. American Parkinson Disease $1,000.00 Corporate Sponsorship Association, Inc. American Peptide Society $1,000.00 Educational Grants American Pharmacists $10,000.00 Corporate Sponsorship Association American Society for Mens $10,000.00 Corporate Sponsorship Health American Society of $15,000.00 Corporate Sponsorship Andrology American Society of $15,000.00 Educational Grants Clinical Oncology American Society of $25,000.00 Educational Grants Clinical Oncology American Society of $15,000.00 Educational Grants Clinical Oncology American Society of $9,500.00 Corporate Sponsorship Clinical Rheumatologists American Society of Health $23,400.00 Corporate Sponsorship System Pharmacists American Socty of $95,000.00 Corporate Sponsorship Hematology American Socty of $2,550.00 Corporate Sponsorship Hematology American Socty of $25,000.00 Corporate Sponsorship Hematology American Socty of $60,000.00 Corporate Sponsorship Hematology American Statistical $2,500.00 Educational Grants Association American Thyroid $45,000.00 Educational Grants Association, Inc. American Uroligical Asoc $11,500.00 Corporate Sponsorship Northeastern Section American Urological Asoc $10,000.00 Corporate Sponsorship Foundation American Urological Asoc $6,000.00 Corporate Sponsorship Inc. North Ctrl Section American Urological Asoc $10,000.00 Corporate Sponsorship Inc. Western Section American Urological Asoc $1,000.00 Corporate Sponsorship New York Section American Urological Asoc $6,000.00 Corporate Sponsorship South Ctrl Section American Urological $100,000.00 Corporate Sponsorship Association American Urological $25,000.00 Corporate Sponsorship Association American Urological $37,500.00 Corporate Sponsorship Association American Urological $41,000.00 Corporate Sponsorship Association American Urological $75,000.00 Educational Grants Association Education And Research, Inc. American Urological $50,000.00 Educational Grants Association Education And Research, Inc. American Urological $30,000.00 Educational Grants Association Education And Research, Inc. American Urological $10,000.00 Educational Grants Association Education And Research, Inc. American Urological $10,000.00 Educational Grants Association Education And Research, Inc. American Urological $10,000.00 Educational Grants Association Education And Research, Inc. American Urological $25,000.00 Educational Grants Association Education And Research, Inc. American Urological $10,000.00 Educational Grants Association Education And Research, Inc. American Urological $8,000.00 Educational Grants Association Education And Research, Inc. Americans for Medical $110,000.00 Charitable Donation Progress Educational Found Americares Foundation, Inc. $10,000.00 Corporate Sponsorship Anesthesia Patient Safety $15,000.00 Charitable Donation Foundation Annenberg Center for Health $50,000.00 Educational Grants Science Annenberg Center for Health $140,000.00 Educational Grants Science Annenberg Center for Health $90,000.00 Educational Grants Science Annenberg Center for Health $641,628.00 Educational Grants Science Annenberg Center for Health $85,000.00 Educational Grants Science Annenberg Center for Health $75,000.00 Educational Grants Science Annenberg Center for Health ($5,000.00) Educational Grants Science Arizona United Rheum $5,000.00 Corporate Sponsorship Alliance Aura Arthritis Foundation, Inc. $5,000.00 Corporate Sponsorship Arthritis Foundation, Inc. $5,000.00 Corporate Sponsorship Arthritis Foundation, Inc. $50,000.00 Educational Grants Arthritis Foundation, Inc. $30,000.00 Corporate Sponsorship Arthritis Foundation, Inc. $10,000.00 Educational Grants Arthritis Foundation, Inc. $2,500.00 Patient Support Arthritis Foundation, Inc. $30,000.00 Corporate Sponsorship Arthritis Foundation, Inc. $40,000.00 Patient Support Arthritis Foundation, Inc. $20,000.00 Corporate Sponsorship Arthritis Foundation, Inc. $12,500.00 Patient Support Arthritis Foundation, Inc. $25,000.00 Corporate Sponsorship Arthritis Foundation, Inc. $25,000.00 Corporate Sponsorship Arthritis Foundation, Inc. $1,500.00 Corporate Sponsorship Arthritis Foundation, Inc. $5,000.00 Corporate Sponsorship Arthritis Foundation, Inc. $5,000.00 Corporate Sponsorship Arthritis Foundation, Inc. $5,000.00 Corporate Sponsorship Arthritis Foundation, Inc. $2,000.00 Corporate Sponsorship Arthritis Foundation, Inc. $3,000.00 Corporate Sponsorship Arthritis Foundation, Inc. $1,000.00 Corporate Sponsorship Arthritis Foundation, Inc. $5,000.00 Corporate Sponsorship Arthritis Foundation, Inc. $2,000.00 Corporate Sponsorship Arthritis Foundation, Inc. $1,000.00 Corporate Sponsorship Arthritis Foundation, Inc. $2,500.00 Patient Support Arthritis Foundation, Inc. $5,000.00 Corporate Sponsorship Arthritis Foundation, Inc. $30,000.00 Corporate Sponsorship Arthritis Foundation, Inc. $250,000.00 Corporate Sponsorship Arthritis Foundation, Inc. $175,000.00 Corporate Sponsorship Arthritis Foundation, Inc. $300,000.00 Corporate Sponsorship Arthritis Foundation, Inc. $300,000.00 Corporate Sponsorship Arthritis Foundation, Inc. $259,000.00 Corporate Sponsorship Arthritis Patient Services $10,000.00 Educational Grants Arthritis Patient Services $25,000.00 Educational Grants Asco Cancer Foundation $50,000.00 Charitable Donation Asco Cancer Foundation $40,000.00 Fellowships or Scholarships Asco Cancer Foundation ($689.37) Fellowships or Scholarships Asociacion De Hematologia Y $5,000.00 Corporate Sponsorship Oncologia Medica De Puerto Rico Asociacion De Reumatologos $22,500.00 Corporate Sponsorship De Puerto Rico Asociacion De Salud $2,000.00 Corporate Sponsorship Primaria De Puerto Rico, Inc. Asociacion Pr De $10,000.00 Corporate Sponsorship Gastroenterologia Asociacion Pr De $40,000.00 Corporate Sponsorship Gastroenterologia Asociacion Pr De $30,000.00 Corporate Sponsorship Gastroenterologia Asociacion Puertorriquena $2,500.00 Corporate Sponsorship De Ayuda Al Paciente De Psiorasis Asociacion Puertorriquena $15,000.00 Corporate Sponsorship De Medicina Fisica Y Rehabilitacion Asociacion Puertorriquena $6,000.00 Corporate Sponsorship De Medicina Fisica Y Rehabilitacion Aspen Cancer Conference, $7,500.00 Educational Grants Inc. Association for Assessment $5,000.00 Charitable Donation And Accreditation of Laboratory Animal Care International Association of Physician $10,000.00 Corporate Sponsorship Assistants In Oncology Inc. Association of Women in $30,000.00 Corporate Sponsorship Rheumatology Association of Women in $30,000.00 Corporate Sponsorship Rheumatology At Point of Care, LLC $150,000.00 Educational Grants Autoimmune Advocacy $2,500.00 Corporate Sponsorship Alliance Baehr Challenge Ltd. $2,500.00 Corporate Sponsorship Baehr Challenge Ltd. $4,000.00 Corporate Sponsorship Balm In Gilead Inc. $75,000.00 Corporate Sponsorship Baylor College of Medicine $5,000.00 Educational Grants Baylor College of Medicine $5,000.00 Corporate Sponsorship Baylor Health Care System $40,000.00 Fellowships or Foundation Scholarships Baylor Univ Med Ctr. $40,000.00 Educational Grants Beth Israel Deaconess $35,000.00 Fellowships or Medical Center Scholarships Beth Israel Deaconess $40,000.00 Fellowships or Medical Center Scholarships Beth Israel Deaconess $25,000.00 Fellowships or Medical Center Scholarships Beth Israel Deaconess $8,000.00 Educational Grants Medical Center Bioconnections LLC $125,000.00 Corporate Sponsorship Board of Trustees of The $40,000.00 Fellowships or University of Illinois Scholarships Board of Trustees of The $1,500.00 Educational Grants University of Illinois Boomer Esiason Foundation $25,000.00 Corporate Sponsorship Boomer Esiason Foundation $400,000.00 Corporate Sponsorship Borland Groover Foundation $1,000.00 Corporate Sponsorship Boston Univ School of $70,000.00 Educational Grants Medicine Boston Univ School of $125,000.00 Educational Grants Medicine Boston Univ School of $1,500.00 Educational Grants Medicine Boston Univ School of $5,000.00 Corporate Sponsorship Medicine Boston Univ School of $10,000.00 Educational Grants Medicine Boston University Mdcn ($3,402.40) Educational Grants Psychtry Brandeis University $1,250.00 Charitable Donation Breast Friends $1,500.00 Corporate Sponsorship Business Hlth Coalition $3,300.00 Corporate Sponsorship Foundation Butler University $1,250.00 Charitable Donation California Association for $1,500.00 Corporate Sponsorship Nurse Practitioners California Healthcare $1,500.00 Corporate Sponsorship Institute California Life Sciences $5,000.00 Corporate Sponsorship Association California Life Sciences $1,500.00 Corporate Sponsorship Association California Socty of $10,000.00 Corporate Sponsorship Dermatology & Dermatology Surgry Cancer Care $2,500.00 Educational Grants Cancer Care $2,500.00 Educational Grants Cancer Care ($2,500.00) Educational Grants Cancer Care $25,000.00 Educational Grants Cancer Care $25,000.00 Educational Grants Cancer Molecular $5,000.00 Educational Grants Therapeutics Research Association Capital Meeting Planning $2,000.00 Educational Grants Inc. Caribe Gyn, Inc. $5,000.00 Corporate Sponsorship Casa Lake County $10,000.00 Corporate Sponsorship Catholic Charities of The $8,500.00 Corporate Sponsorship Archdiocese of Chicago Cedars-Sinai Medical Center $40,000.00 Fellowships or Scholarships Cedars-Sinai Medical Center ($4,000.00) Educational Grants Central Florida Pharmacy $15,000.00 Patient Support Council Central Savannah River Area $1,000.00 Corporate Sponsorship Csra Parkinson Support Group Chicago Help Initiative $7,500.00 Charitable Donation Childhood Arthritis And $35,000.00 Corporate Sponsorship Rheumatology Research Alliance Carra Children And Arthritis, $4,500.00 Charitable Donation Inc. Childrens Digestive Hlth $40,000.00 Fellowships or And Nutrition Foundation Scholarships Childrens Digestive Hlth ($40,000.00) Fellowships or And Nutrition Foundation Scholarships Childrens Digestive Hlth $56,000.00 Educational Grants And Nutrition Foundation Childrens Digestive Hlth $10,000.00 Corporate Sponsorship And Nutrition Foundation Childrens Digestive Hlth $2,500.00 Corporate Sponsorship And Nutrition Foundation Chimp Haven, Inc. $25,000.00 Charitable Donation Chronic Liver Disease $1,000,000.00 Educational Grants Foundation Chronic Liver Disease $364,315.00 Educational Grants Foundation Chronic Liver Disease $1,513,875.00 Educational Grants Foundation Chronic Liver Disease ($2,700.00) Educational Grants Foundation Chronic Liver Disease ($9,044.17) Educational Grants Foundation Chronic Liver Disease ($9,045.00) Educational Grants Foundation Chronic Liver Disease $27,500.00 Corporate Sponsorship Foundation Chronic Lymphoytic Leukemia $25,000.00 Charitable Donation Society, Inc. Chronic Lymphoytic Leukemia $25,000.00 Educational Grants Society, Inc. Chronic Lymphoytic Leukemia $10,000.00 Patient Support Society, Inc. Cincinnati Childrens $40,000.00 Educational Grants Hospital Cincinnati Childrens $22,500.00 Corporate Sponsorship Hospital Medical Center Pulmonary Medicine Cleveland Clinic Foundation $3,000.00 Educational Grants Cleveland Clinic Foundation $50,000.00 Fellowships or Scholarships Cleveland Clinic Foundation $40,000.00 Fellowships or Scholarships Cleveland Clinic Minority $5,000.00 Educational Grants Men's Health Center Cleveland Clnc Educational ($542.72) Educational Grants Foundation The Cleveland Clnc Educational $50,000.00 Educational Grants Foundation The Cleveland Clnc Educational $50,000.00 Educational Grants Foundation The Cleveland Clnc Educational ($6,109.89) Educational Grants Foundation The Cleveland Clnc Educational ($1,147.40) Educational Grants Foundation The Clinical Care Options, LLC $75,000.00 Educational Grants Clinical Care Options, LLC $100,000.00 Educational Grants Clinical Care Options, LLC $75,000.00 Educational Grants Clinical Care Options, LLC $100,000.00 Educational Grants Cll Global Research $15,000.00 Educational Grants Foundation Cll Global Research $25,000.00 Educational Grants Foundation Coalition for Prevention of $5,000.00 Corporate Sponsorship Colorectal Cancer In Puerto Rico Coalition for Prevention of $3,000.00 Corporate Sponsorship Colorectal Cancer In Puerto Rico Colegio De Medicos $20,000.00 Educational Grants Cirujanos De Puerto Rico Columbia Univ Med Ctr $1,250.00 Charitable Donation Community Health $10,000.00 Corporate Sponsorship Community Health $10,000.00 Corporate Sponsorship Community Health $10,000.00 Corporate Sponsorship Community Health And Men's $5,000.00 Patient Support Promotion Summit Community Initiatives $5,000.00 Corporate Sponsorship Community Initiatives $57,000.00 Corporate Sponsorship Community Initiatives $50,000.00 Corporate Sponsorship Community Liver Alliance $5,000.00 Corporate Sponsorship Complete Conference Mgmt ($916.00) Educational Grants Connect1D $2,500.00 Corporate Sponsorship Connecticut Academy of $1,700.00 Corporate Sponsorship Physician Assistants Connecticut Advocates for $500.00 Corporate Sponsorship Parkinsons Inc. Connecting To Cure Crohns $5,000.00 Corporate Sponsorship And Colitis Consortium of Multiple $25,000.00 Educational Grants Sclerosis Centers Continuing Education $400,000.00 Educational Grants Alliance, LLC Continuing Education $350,000.00 Educational Grants Alliance, LLC Continuing Education ($1,972.99) Educational Grants Alliance, LLC Continuing Education ($5,392.00) Educational Grants Alliance, LLC Continuing Education ($723.11) Educational Grants Alliance, LLC Continuing Education ($3,353.94) Educational Grants Alliance, LLC Continuing Education $439,195.00 Educational Grants Alliance, LLC Continuing Education ($1,553.15) Educational Grants Alliance, LLC Continuing Education ($1,523.00) Educational Grants Alliance, LLC Continuing Education ($567.24) Educational Grants Alliance, LLC Cope Coalition On Positive $20,000.00 Corporate Sponsorship Health Empowerment Cope Coalition On Positive $15,000.00 Corporate Sponsorship Health Empowerment Core Foundation $10,000.00 Corporate Sponsorship Cornell University Weill $2,500.00 Educational Grants Cornell Medical College Cornell University Weill $2,500.00 Educational Grants Cornell Medical College Cornerstones Health Inc. $90,000.00 Educational Grants Cornerstones Health Inc. ($20,375.00) Educational Grants Cornerstones Health Inc. $75,000.00 Educational Grants Crape Myrtle Festival $300.00 Corporate Sponsorship Creighton University $7,500.00 Educational Grants Crohn's and Colitis $400,000.00 Corporate Sponsorship Foundation of America, Inc. Crohn's and Colitis $22,500.00 Corporate Sponsorship Foundation of America, Inc. Crohn's and Colitis $5,000.00 Corporate Sponsorship Foundation of America, Inc. Crohn's and Colitis $1,200,000.00 Educational Grants Foundation of America, Inc. Crohn's and Colitis $180,000.00 Educational Grants Foundation of America, Inc. Crohn's and Colitis $5,000.00 Corporate Sponsorship Foundation of America, Inc. Crohn's and Colitis ($265.00) Educational Grants Foundation of America, Inc. Crohn's and Colitis $50,160.00 Corporate Sponsorship Foundation of America, Inc. Crohn's and Colitis $3,000.00 Corporate Sponsorship Foundation of America, Inc. Crohn's and Colitis $2,500.00 Corporate Sponsorship Foundation of America, Inc. Crohn's and Colitis $1,000.00 Corporate Sponsorship Foundation of America, Inc. Crohn's and Colitis $25,000.00 Charitable Donation Foundation of America, Inc. Crohn's and Colitis $25,000.00 Charitable Donation Foundation of America, Inc. Crohn's and Colitis $90,000.00 Corporate Sponsorship Foundation of America, Inc. Crohn's and Colitis $35,000.00 Educational Grants Foundation of America, Inc. Crohn's and Colitis $2,500.00 Corporate Sponsorship Foundation of America, Inc. Crohn's and Colitis $5,000.00 Corporate Sponsorship Foundation of America, Inc. Crohn's and Colitis $1,500.00 Corporate Sponsorship Foundation of America, Inc. Crohn's and Colitis $5,000.00 Corporate Sponsorship Foundation of America, Inc. Crohn's and Colitis $10,000.00 Corporate Sponsorship Foundation of America, Inc. Crohn's and Colitis $100,000.00 Fellowships or Foundation of America, Scholarships Inc. Crohn's and Colitis $32,500.00 Corporate Sponsorship Foundation of America, Inc. Crohn's and Colitis $10,000.00 Corporate Sponsorship Foundation of America, Inc. Crohn's and Colitis $1,000.00 Corporate Sponsorship Foundation of America, Inc. Crohn's and Colitis $1,500.00 Corporate Sponsorship Foundation of America, Inc. Crohn's and Colitis $90,000.00 Corporate Sponsorship Foundation of America, Inc. Crohn's and Colitis $10,000.00 Corporate Sponsorship Foundation of America, Inc. Crohn's and Colitis $400,000.00 Corporate Sponsorship Foundation of America, Inc. Crohn's and Colitis $22,500.00 Corporate Sponsorship Foundation of America, Inc. Culinary Care $2,500.00 Corporate Sponsorship Curatio Cme Inst ($3,261.00) Educational Grants Curatio Cme Inst ($180.00) Educational Grants Curatio Cme Inst ($50,000.00) Educational Grants Curatio Cme Inst ($8,855.73) Educational Grants Cure CF $500.00 Corporate Sponsorship Cystic Fibrosis Foundation $10,000.00 Corporate Sponsorship Cystic Fibrosis Foundation $5,000.00 Corporate Sponsorship Cystic Fibrosis Foundation $2,500.00 Corporate Sponsorship Cystic Fibrosis Foundation $3,000.00 Corporate Sponsorship Cystic Fibrosis Foundation $1,000.00 Corporate Sponsorship Cystic Fibrosis Foundation $1,500.00 Corporate Sponsorship Cystic Fibrosis Foundation $3,750.00 Corporate Sponsorship Cystic Fibrosis Foundation $500,000.00 Corporate Sponsorship Cystic Fibrosis Foundation $2,500.00 Corporate Sponsorship Cystic Fibrosis Foundation $100,000.00 Charitable Donation Cystic Fibrosis Foundation $2,500.00 Corporate Sponsorship Cystic Fibrosis Foundation $2,000.00 Corporate Sponsorship Cystic Fibrosis Foundation $1,500.00 Corporate Sponsorship Cystic Fibrosis Foundation $1,000.00 Corporate Sponsorship Cystic Fibrosis Foundation $1,000.00 Corporate Sponsorship Cystic Fibrosis Foundation $2,500.00 Corporate Sponsorship Cystic Fibrosis Foundation $2,000.00 Corporate Sponsorship Cystic Fibrosis Foundation $1,000.00 Corporate Sponsorship Cystic Fibrosis Foundation $5,000.00 Corporate Sponsorship Cystic Fibrosis Foundation $7,500.00 Corporate Sponsorship Cystic Fibrosis Foundation $3,000.00 Corporate Sponsorship Cystic Fibrosis Foundation $1,000.00 Corporate Sponsorship Cystic Fibrosis Foundation $10,000.00 Corporate Sponsorship Cystic Fibrosis Foundation $1,500.00 Corporate Sponsorship Cystic Fibrosis Foundation $50,000.00 Corporate Sponsorship Cystic Fibrosis Foundation $3,500.00 Corporate Sponsorship Cystic Fibrosis Foundation $1,500.00 Corporate Sponsorship Cystic Fibrosis Foundation $1,000.00 Corporate Sponsorship Cystic Fibrosis Foundation $2,000.00 Corporate Sponsorship Cystic Fibrosis Foundation $2,000.00 Corporate Sponsorship Cystic Fibrosis Foundation $1,000.00 Corporate Sponsorship Cystic Fibrosis Foundation $2,500.00 Corporate Sponsorship Cystic Fibrosis Foundation $2,500.00 Corporate Sponsorship Cystic Fibrosis Foundation $25,000.00 Corporate Sponsorship Cystic Fibrosis Foundation $15,000.00 Corporate Sponsorship Cystic Fibrosis Foundation $2,500.00 Corporate Sponsorship Cystic Fibrosis Foundation $1,000.00 Corporate Sponsorship Cystic Fibrosis Foundation $750.00 Corporate Sponsorship Cystic Fibrosis Foundation $1,000.00 Corporate Sponsorship Cystic Fibrosis Foundation $3,000.00 Corporate Sponsorship Cystic Fibrosis Foundation $2,000.00 Corporate Sponsorship Cystic Fibrosis Foundation $3,750.00 Corporate Sponsorship Cystic Fibrosis Foundation $750,000.00 Corporate Sponsorship Cystic Fibrosis Foundation $1,500.00 Corporate Sponsorship Cystic Fibrosis Foundation $16,000.00 Corporate Sponsorship Cystic Fibrosis Foundation $1,000.00 Corporate Sponsorship Cystic Fibrosis Foundation $2,500.00 Corporate Sponsorship Cystic Fibrosis Foundation $2,500.00 Corporate Sponsorship Cystic Fibrosis Foundation $2,500.00 Corporate Sponsorship Cystic Fibrosis Foundation $2,500.00 Corporate Sponsorship Cystic Fibrosis Foundation $2,500.00 Corporate Sponsorship Cystic Fibrosis Foundation $2,500.00 Corporate Sponsorship Cystic Fibrosis Research $5,000.00 Corporate Sponsorship Fund Emily's Entourage Cystic Fibrosis Research $1,250.00 Corporate Sponsorship Inc. Cystic Fibrosis Research $3,000.00 Corporate Sponsorship Inc. Cystic Fibrosis Research $15,000.00 Corporate Sponsorship Inc. Cystic Fibrosis Research $10,000.00 Corporate Sponsorship Inc. Dallas Fort Worth Business $5,000.00 Corporate Sponsorship Group on Health Dava Oncology LP $95,000.00 Corporate Sponsorship Davis Phinney Foundation $30,000.00 Educational Grants Davis Phinney Foundation $30,000.00 Educational Grants Davis Phinney Foundation $40,000.00 Patient Support Dermatology Education $30,000.00 Corporate Sponsorship Foundation Dermatology Foundation $40,000.00 Fellowships or Scholarships Dermatology Foundation $135,000.00 Charitable Donation Dermatology Foundation $50,000.00 Corporate Sponsorship Dermatology Nurses $15,000.00 Educational Grants Association Dermatology Nurses $23,270.00 Corporate Sponsorship Association Dermatology Nurses $25,850.00 Corporate Sponsorship Association Desert Aids Project Inc. $2,000.00 Corporate Sponsorship Digestive Disease Week $55,000.00 Corporate Sponsorship Digestive Disease Week $3,500.00 Corporate Sponsorship Digestive Health Foundation $25,000.00 Corporate Sponsorship Duke University $40,000.00 Fellowships or Scholarships Duke University ($780.00) Educational Grants Duke University Medical $10,000.00 Fellowships or Center Scholarships East Hawaii IPA $8,000.00 Corporate Sponsorship Efficient Collaborative $28,100.00 Corporate Sponsorship Retail Marketing Eicosanoid Research $2,000.00 Educational Grants Foundation El Centro Regional Medical $5,000.00 Corporate Sponsorship Center Foundation El Centro Regional Medical $5,000.00 Corporate Sponsorship Center Foundation Elsevier Inc. $150,000.00 Educational Grants Emory University $10,000.00 Corporate Sponsorship Emory University $2,000.00 Corporate Sponsorship Emory University $10,000.00 Corporate Sponsorship Emory University School of $25,000.00 Educational Grants Medicine Employers Health Coalition $4,000.00 Corporate Sponsorship Inc. Endocrine Society $10,000.00 Corporate Sponsorship Endocrine Society $15,000.00 Educational Grants Endometriosis Foundation of $2,500.00 Corporate Sponsorship America Epilepsy Foundation $15,000.00 Charitable Donation Erie Family Health Center $5,000.00 Sponsorship Corporate Escuela De Medicina De $8,000.00 Educational Grants Ponce Escuela De Medicina San $40,000.00 Fellowships or Juan Bautista Scholarships Evergreen Foundation of $750.00 Corporate Sponsorship Western New York Excellence In Rheumatology $100,000.00 Corporate Sponsorship Education LLC Facing Our Risk of Cancer $15,000.00 Educational Grants Empowerement Force Federation of American $5,000.00 Corporate Sponsorship Societies for Experimental Biology Federation of American $1,500.00 Educational Grants Societies for Experimental Biology Federation of American $1,500.00 Educational Grants Societies for Experimental Biology Federation of American $1,500.00 Educational Grants Societies for Experimental Biology Federation of American $1,500.00 Educational Grants Societies for Experimental Biology Federation of Clinical $18,000.00 Educational Grants Immunology Societies Federation of Clinical $15,000.00 Educational Grants Immunology Societies Florida Health Care $10,000.00 Corporate Sponsorship Coalition Florida Health Care $4,500.00 Corporate Sponsorship Coalition Florida Society of $25,000.00 Corporate Sponsorship Rheumatology Focus Medical $150,000.00 Corporate Sponsorship Communications LLC Food Outreach $10,000.00 Corporate Sponsorship force--Facing Our Risk of $5,000.00 Corporate Sponsorship Cancer Emp Foundation for Anesthesia $15,000.00 Fellowships or Education And Research Scholarships Foundation for Arthritis $5,500.00 Corporate Sponsorship Treatment Foundation for The National $10,000.00 Corporate Sponsorship Institutes of Health Foundation for Veterans $25,000.00 Corporate Sponsorship Health Care Foundation of Consortium of $8,000.00 Charitable Donation Multiple Sclerosis Centers Cmsc Foundcare Inc. $2,500.00 Corporate Sponsorship Foundcare Inc. $2,500.00 Corporate Sponsorship Friends of Cancer Research $30,000.00 Corporate Sponsorship Friends of Parkinsons $2,500.00 Corporate Sponsorship Friends of Prentice $25,000.00 Charitable Donation Fundacion De Investigacion $25,000.00 Educational Grants Gastro Intestinal Research $50,000.00 Corporate Sponsorship Foundation Gastro Intestinal Research $25,000.00 Corporate Sponsorship Foundation Gastrointestinal And Liver $75,000.00 Educational Grants Association of The Americas Inc. Gateway for Cancer Research $6,000.00 Corporate Sponsorship General Hospital $10,000.00 Educational Grants Corporation Georgia Dermatology $7,500.00 Corporate Sponsorship Physician Assistants Georgia Dermatology $15,000.00 Corporate Sponsorship Physician Assistants Georgia Health Sciences $1,500.00 Educational Grants Foundation Inc. Georgia Prostate Cancer $5,000.00 Patient Support Coalition Georgia Society of $3,000.00 Corporate Sponsorship Dermatology And Dermatologic Surgery Gilda's Club Chicago $25,000.00 Corporate Sponsorship Global Academy for Medical $72,000.00 Corporate Sponsorship Education Global Academy for Medical $35,000.00 Corporate Sponsorship Education Global Academy for Medical $18,000.00 Corporate Sponsorship Education Global Academy for Medical $72,000.00 Corporate Sponsorship Education Global Academy for Medical $72,000.00 Corporate Sponsorship Education Global Academy for Medical $45,000.00 Corporate Sponsorship Education Global Alliance for Patient $30,000.00 Corporate Sponsorship Access Global Alliance for Patient $50,000.00 Corporate Sponsorship Access Global Alliance for Patient $50,000.00 Corporate Sponsorship Access Global Alliance for Patient $250,000.00 Educational Grants Access Global Healthy Living $24,000.00 Corporate Sponsorship Foundation Global Healthy Living $25,000.00 Corporate Sponsorship Foundation Gordon Research Conferences $1,500.00 Educational Grants Gordon Research Conferences $1,500.00 Educational Grants Gordon Research Conferences $1,500.00 Educational Grants Gordon Research Conferences $1,500.00 Educational Grants Gordon Research Conferences $2,000.00 Educational Grants Gordon Research Conferences $2,500.00 Educational Grants Gordon Research Conferences $2,000.00 Educational Grants Gordon Research Conferences $1,500.00 Educational Grants Gordon Research Conferences $1,500.00 Educational Grants Gordon Research Conferences $1,500.00 Educational Grants Gordon Research Conferences $1,500.00 Educational Grants Gordon Research Conferences $1,000.00 Educational Grants Gospel Heritage Foundation $10,000.00 Corporate Sponsorship Great Lakes Chapter of The $1,000.00 Corporate Sponsorship American Society for Pharmacology And Experimental Therapeutics Group of Research And $15,000.00 Corporate Sponsorship Assessment of Psoriasis And Psoriatic Arthritis Grupo De Apoyo De Ninos Y $3,000.00 Corporate Sponsorship Adolescentes Con Reumatologia Gynecologic Oncology Group $25,000.00 Educational Grants Gynecologic Oncology Group $25,000.00 Educational Grants Heals of The South, Inc.-- $5,000.00 Charitable Donation Hepatitis Education Awareness And Liver Support Health Action Council Ohio $3,780.00 Corporate Sponsorship Healthcare 21 Business $5,000.00 Corporate Sponsorship Coalition Healthcare 21 Business $5,000.00 Corporate Sponsorship Coalition Healthcare Financial $50,000.00 Corporate Sponsorship Management Association Hfma Heather Robidoux $7,500.00 Corporate Sponsorship Heb Grocery Company LP $10,000.00 Corporate Sponsorship Hep C Connection $75,000.00 Patient Support Hep C Connection $5,000.00 Corporate Sponsorship Hepatitis Education Project $75,000.00 Charitable Donation Hepatitis Education Project $50,000.00 Corporate Sponsorship Herbert Kosten Pancreatic $2,000.00 Corporate Sponsorship Cancer Charitable Fund Hitchcock Foundation $25,000.00 Educational Grants Hiv Treaters Med Asoc of $10,000.00 Educational Grants Puerto Rico HMP Communications LLC $40,000.00 Corporate Sponsorship Honor Health Virginia G $800.00 Corporate Sponsorship Piper Cancer Center Hope Foundation The $20,000.00 Educational Grants Houston Area Parkinson $2,500.00 Corporate Sponsorship Society Howard Brown Health Center $20,000.00 Corporate Sponsorship Howard Hanna Children's $10,000.00 Charitable Donation Free Care Fund Hubbard Street Dance $10,000.00 Educational Grants Chicago Hughes Healthcare $177,550.00 Educational Grants Disparities Group Human Growth Foundation $5,000.00 Corporate Sponsorship Human Growth Foundation $4,000.00 Corporate Sponsorship Humboldt--Del Norte County $4,000.00 Educational Grants Med Socty Hyacinth Aids Foundation $5,000.00 Corporate Sponsorship Illinois African American $10,000.00 Corporate Sponsorship Coalition Illinois African American $10,000.00 Corporate Sponsorship Coalition Imedex, LLC $40,000.00 Educational Grants Imedex, LLC $30,000.00 Educational Grants Imedex, LLC $40,000.00 Educational Grants Imedex, LLC $15,000.00 Corporate Sponsorship Imedex, LLC $50,000.00 Educational Grants Imedex, LLC $75,000.00 Educational Grants Indiana University $4,100.00 Fellowships or Scholarships Infant Welfare Society of $10,000.00 Charitable Donation Chicago Infectious Diseases Society $25,000.00 Charitable Donation of America Infectious Diseases Society $50,000.00 Educational Grants of America Integrated Benefits $25,000.00 Corporate Sponsorship Institute Inc. Integrated Benefits $25,000.00 Corporate Sponsorship Institute Inc. Integrated Medical $35,000.00 Charitable Donation Foundation Integrated Medical $2,000.00 Corporate Sponsorship Foundation Integrated Medical $2,000.00 Corporate Sponsorship Foundation Integrated Medical $1,000.00 Corporate Sponsorship Foundation Interfaith House $2,000.00 Charitable Donation International Aids Socty-- $200,000.00 Educational Grants USA International Aids Socty-- $80,000.00 Educational Grants USA International Aids Socty-- $75,000.00 Educational Grants USA International Asoc for The $2,500.00 Corporate Sponsorship Study of Lung Cancer IASLC International Association $10,000.00 Educational Grants of Providers of Aids Care International Association $10,000.00 Educational Grants of Providers of Aids Care International Chinese $3,000.00 Educational Grants Statistical Association International Dermatology $70,000.00 Corporate Sponsorship Outcome Measures International Foot And $2,000.00 Corporate Sponsorship Ankle Foundation International League of $20,000.00 Charitable Donation Association for Rheumatology International Liver $10,000.00 Educational Grants Transplantation Society International Liver $40,000.00 Educational Grants Transplantation Society International Medical Corps $5,000.00 Corporate Sponsorship International Psoriasis $100,000.00 Corporate Sponsorship Council International Psoriasis $50,000.00 Corporate Sponsorship Council International Psoriasis $50,000.00 Corporate Sponsorship Council International Psoriasis $50,000.00 Corporate Sponsorship Council International Society for $3,000.00 Educational Grants The Study of Xenbiotics International Society of $2,000.00 Educational Grants Biopharmaceutical Statistics International Society of $1,500.00 Educational Grants Heterocyclic Chemistry Iowa Pharmacy Association $5,000.00 Corporate Sponsorship Johns Hopkins Univ School $75,000.00 Educational Grants of Medicine Johns Hopkins Univ School $25,000.00 Corporate Sponsorship of Medicine Johns Hopkins Univ School $40,000.00 Fellowships or of Medicine Scholarships Johns Hopkins Univ School ($5,646.02) Educational Grants of Medicine Johns Hopkins Univ School $46,213.00 Educational Grants of Medicine Johns Hopkins Univ School $50,000.00 Educational Grants of Medicine JWC Covenant, Inc. $20,000.00 Educational Grants JWC Covenant, Inc. $25,000.00 Corporate Sponsorship JWC Covenant, Inc. $2,500.00 Corporate Sponsorship Kansas University Endowment $500.00 Corporate Sponsorship Association Keck Medical Center of USC $25,000.00 Educational Grants Kelsey Research Foundation $35,000.00 Fellowships or Scholarships Ken Zebrowski Memorial Walk $2,000.00 Corporate Sponsorship Kidney Disease Improving $200,000.00 Corporate Sponsorship Global Outcomes Laboratorio Clinico Toledo $900.00 Patient Support Laboratorio Clinico Toledo $1,365.00 Patient Support Laboratorio Clinico Toledo $1,200.00 Patient Support Laboratorio Clinico Toledo $615.00 Patient Support Laboratorio Clinico Toledo $720.00 Patient Support Laboratorio Clinico Toledo $1,275.00 Patient Support Laboratorio Clinico Toledo $1,365.00 Patient Support Laboratorio Clinico Toledo $1,365.00 Patient Support Laboratorio Clinico Toledo $2,040.00 Patient Support Laboratorio Clinico Toledo $1,500.00 Patient Support Laboratorio Clinico Toledo $1,500.00 Patient Support Laboratorio Clinico Toledo $1,365.00 Patient Support Laboratorio Clinico Toledo $945.00 Patient Support Laboratorio Clinico Toledo $1,320.00 Patient Support Laboratorio Clinico Toledo $3,600.00 Patient Support Laboratorio Clinico Toledo $1,800.00 Patient Support Laboratorio Clinico Toledo $1,500.00 Patient Support Laboratorio Clinico Toledo $1,245.00 Patient Support Laboratorio Clinico Toledo $4,125.00 Patient Support Laboratorio Clinico Toledo $2,220.00 Patient Support Laboratorio Clinico Toledo $2,160.00 Patient Support Laboratorio Clinico Toledo $1,605.00 Patient Support Laboratorio Clinico Toledo $2,040.00 Patient Support Laboratorio Clinico Toledo $1,500.00 Patient Support Laboratorio Clinico Toledo $1,500.00 Patient Support Laboratorio Clinico Toledo $1,455.00 Patient Support Laboratorio Clinico Toledo $1,650.00 Patient Support Laboratorio Clinico Toledo $1,365.00 Patient Support Laboratorio Clinico Toledo $360.00 Patient Support Laboratorio Clinico Toledo $876.00 Patient Support Laboratorio Clinico Toledo $1,110.00 Patient Support Laboratorio Clinico Toledo $1,470.00 Patient Support Laboratorio Clinico Toledo $2,715.00 Patient Support Laboratorio Clinico Toledo $1,140.00 Patient Support Laboratorio Clinico Toledo $1,770.00 Patient Support Laboratorio Clinico Toledo $1,500.00 Patient Support Laboratorio Clinico Toledo $1,485.00 Patient Support Laboratorio Clinico Toledo $1,455.00 Patient Support Laboratorio Clinico Toledo $1,335.00 Patient Support Laboratorio Clinico Toledo $1,095.00 Patient Support Laboratorio Clinico Toledo $1,500.00 Patient Support Laboratorio Clinico Toledo $1,500.00 Patient Support Laboratorio Clinico Toledo $1,380.00 Patient Support Laboratorio Clinico Toledo $1,500.00 Patient Support Laboratorio Clinico Toledo $1,215.00 Patient Support Laboratorio Clinico Toledo $975.00 Patient Support Laboratorio Clinico Toledo $945.00 Patient Support Laboratorio Clinico Toledo $825.00 Patient Support Laboratorio Clinico Toledo $1,140.00 Patient Support Laboratorio Clinico Toledo $2,730.00 Patient Support Laboratorio Clinico Toledo $1,065.00 Patient Support Laboratorio Clinico Toledo $990.00 Patient Support Laboratorio Clinico Toledo $1,980.00 Patient Support Laboratorio Clinico Toledo $2,610.00 Patient Support Laboratorio Clinico Toledo $1,650.00 Patient Support Laboratorio Clinico Toledo $2,190.00 Patient Support Laboratorio Clinico Toledo $855.00 Patient Support Laboratorio Clinico Toledo $1,785.00 Patient Support Laboratorio Clinico Toledo $276.00 Patient Support Laboratorio Clinico Toledo $1,680.00 Patient Support Laboratorio Clinico Toledo $510.00 Patient Support Laboratorio Clinico Toledo $1,200.00 Patient Support Laboratorio Clinico Toledo $525.00 Patient Support Laboratorio Clinico Toledo $1,335.00 Patient Support Laboratorio Clinico Toledo $1,650.00 Patient Support Laboratorio Clinico Toledo $630.00 Patient Support Laboratorio Clinico Toledo $990.00 Patient Support Laboratorio Clinico Toledo $1,020.00 Patient Support Laboratorio Clinico Toledo $1,275.00 Patient Support Laboratorio Clinico Toledo $1,395.00 Patient Support Laboratorio Clinico Toledo $315.00 Patient Support Laboratorio Clinico Toledo $1,500.00 Patient Support Laboratorio Clinico Toledo $1,290.00 Patient Support Laboratorio Clinico Toledo $1,275.00 Patient Support Laboratorio Clinico Toledo $525.00 Patient Support Laboratorio Clinico Toledo $510.00 Patient Support Laboratorio Clinico Toledo $315.00 Patient Support Laboratorio Clinico Toledo $1,035.00 Patient Support Laboratorio Clinico Toledo $240.00 Patient Support Laboratorio Clinico Toledo $1,065.00 Patient Support Laboratorio Clinico Toledo $660.00 Patient Support Laboratorio Clinico Toledo $1,500.00 Patient Support Laboratorio Clinico Toledo $900.00 Patient Support Laboratorio Clinico Toledo $900.00 Patient Support Laboratorio Clinico Toledo $810.00 Patient Support Laboratorio Clinico Toledo $1,020.00 Patient Support Laboratorio Clinico Toledo $1,200.00 Patient Support Laboratorio Clinico Toledo $3,000.00 Patient Support Laboratorio Clinico Toledo $1,500.00 Patient Support Laboratorio Clinico Toledo $2,400.00 Patient Support Laboratorio Clinico Toledo $465.00 Patient Support Laboratorio Clinico Toledo $1,500.00 Patient Support Laboratorio Clinico Toledo $1,410.00 Patient Support Laboratorio Clinico Toledo $825.00 Patient Support Laboratorio Clinico Toledo $525.00 Patient Support Laboratorio Clinico Toledo $444.00 Patient Support Laboratorio Clinico Toledo $645.00 Patient Support Laboratorio Clinico Toledo $1,125.00 Patient Support Laboratorio Clinico Toledo $1,185.00 Patient Support Laboratorio Clinico Toledo $1,320.00 Patient Support Laboratorio Clinico Toledo $2,160.00 Patient Support Laboratorio Clinico Toledo $1,740.00 Patient Support Lake County Haven $10,000.00 Corporate Sponsorship Large Urology Group $20,000.00 Corporate Sponsorship Practice Association Large Urology Group $15,000.00 Corporate Sponsorship Practice Association Large Urology Group $66,400.00 Corporate Sponsorship Practice Association Large Urology Group $25,000.00 Corporate Sponsorship Practice Association Leading Edge US LLC $125,000.00 Educational Grants Leukemia and Lymphoma $5,000.00 Educational Grants Society Leukemia and Lymphoma $2,500.00 Educational Grants Society Leukemia and Lymphoma $15,000.00 Corporate Sponsorship Society Leukemia and Lymphoma $100,000.00 Corporate Sponsorship Society Leukemia Research $10,000.00 Corporate Sponsorship Foundation Leukemia Research $10,000.00 Corporate Sponsorship Foundation Leukemia Research $20,000.00 Corporate Sponsorship Foundation Leukemia Research $5,000.00 Corporate Sponsorship Foundation Life Sciences Foundation $30,000.00 Charitable Donation Los Angeles Urological $8,500.00 Corporate Sponsorship Society Louisiana State Univ Hlth ($9,779.71) Fellowships or Scnc Ctr Scholarships Louisiana State Univ Hlth $1,200.00 Corporate Sponsorship Scnc Foundation Lupus Research Inst Inc. $50,000.00 Corporate Sponsorship Magellan Health Services $35,000.00 Corporate Sponsorship Main Line Health, Inc. $2,500.00 Educational Grants Map International $25,000.00 Corporate Sponsorship Maryland Dermatologic Socty $75,000.00 Corporate Sponsorship Massachusetts Biotechnology $5,000.00 Corporate Sponsorship Council Massachusetts Institute of $1,250.00 Charitable Donation Technology Massachusetts Institute of $1,250.00 Charitable Donation Technology Massachusetts Prostate $5,000.00 Educational Grants Cancer Coalition Massachusetts Public Health $2,500.00 Corporate Sponsorship Association Massachusetts Public Health $2,500.00 Corporate Sponsorship Association Massachusetts Society for $5,000.00 Educational Grants Medical Research Max Foundation $45,000.00 Corporate Sponsorship Medina Community Clinic $1,000.00 Corporate Sponsorship Med-IQ, LLC $200,000.00 Educational Grants Med-IQ, LLC $156,924.00 Educational Grants Medscape LLC $205,000.00 Educational Grants Medscape LLC $1,000.00 Educational Grants Medscape LLC $175,000.00 Educational Grants Medscape LLC $300,000.00 Educational Grants Medscape LLC $150,000.00 Educational Grants Medscape LLC $150,000.00 Educational Grants Medscape LLC $50,000.00 Educational Grants Medscape LLC $190,000.00 Educational Grants Medscape LLC $250,000.00 Educational Grants Medscape LLC $60,000.00 Educational Grants Medscape LLC $50,000.00 Educational Grants Medscape LLC $8,000.00 Educational Grants Medscape LLC $150,000.00 Educational Grants Memorial Hermann Foundation $35,000.00 Fellowships or Scholarships Memphis Business Group on $5,120.00 Corporate Sponsorship Health Memphis Business Group on $6,500.00 Corporate Sponsorship Health Men Educating Men, Inc. $20,000.00 Patient Support Mercer County Joint Twnshp ($336.00) Educational Grants Commty Hosp Dba Mercer Hlth Mercer County Joint Twnshp $3,000.00 Patient Support Commty Hosp Dba Mercer Hlth Methodist Hosp The $25,000.00 Corporate Sponsorship Mexican American $5,000.00 Corporate Sponsorship Legislative Leadership Foundation Michael J Fox Foundation $69,500.00 Educational Grants Michael J Fox Foundation $25,000.00 Corporate Sponsorship Michael J Fox Foundation $50,000.00 Corporate Sponsorship Michael J Fox Foundation $7,500.00 Corporate Sponsorship Michigan Parkinson $2,000.00 Corporate Sponsorship Foundation Michigan Rheumatism Society $15,000.00 Corporate Sponsorship Mid Atlantic Business Group $7,500.00 Corporate Sponsorship Heatlh Midwest Business Group on $1,000.00 Corporate Sponsorship Health Midwest Pediatric Endocrine $6,300.00 Corporate Sponsorship Society Military officers $10,000.00 Corporate Sponsorship Association of America Family Initiative Minnesota Urological $2,500.00 Corporate Sponsorship Society Mississippi $1,000.00 Corporate Sponsorship Gastroenterology Society Mississippi $1,500.00 Corporate Sponsorship Gastroenterology Society Missouri Hepatitis C $25,000.00 Educational Grants Alliance Missouri Hepatitis C $25,000.00 Educational Grants Alliance Missouri Hepatitis C $25,000.00 Charitable Donation Alliance Montefiore Medical Center $25,000.00 Educational Grants Montefiore Medical Center $75,000.00 Educational Grants Montefiore Medical Center ($10,457.00) Educational Grants Mount Sinai School of $8,000.00 Corporate Sponsorship Medicine Mount Sinai School of $250,000.00 Educational Grants Medicine Mount Sinai School of $15,000.00 Educational Grants Medicine Mount Sinai School of $40,000.00 Educational Grants Medicine Mount Sinai School of $5,000.00 Educational Grants Medicine Mount Sinai School of $20,000.00 Educational Grants Medicine Mount Sinai School of $200,000.00 Educational Grants Medicine Movement Disorder Socty The $172,000.00 Corporate Sponsorship Movement Disorder Socty The $111,230.00 Educational Grants Movement Disorder Socty The $184,500.00 Corporate Sponsorship Multiple Myeloma Research $10,000.00 Educational Grants Foundation My Gut Instinct Inc. $1,500.00 Corporate Sponsorship National Academy of $30,000.00 Corporate Sponsorship Dermatology Nurse Practitioners National Academy of $30,000.00 Corporate Sponsorship Dermatology Nurse Practitioners National AIDS Treatment $150,000.00 Patient Support Advocacy Project National AIDS Treatment $300,000.00 Charitable Donation Advocacy Project National Alliance of Mental $5,000.00 Corporate Sponsorship Illness Michigan National Alliance of Mental $2,500.00 Corporate Sponsorship Illness Oregon National Alliance of Mental $2,500.00 Corporate Sponsorship Illness Washington National Alliance of State $30,000.00 Corporate Sponsorship And Territorial Aids Directors National Alliance of State $75,000.00 Charitable Donation And Territorial Aids Directors National Animal Interest $20,000.00 Charitable Donation Alliance National Association of $25,000.00 Corporate Sponsorship Latino Elected & Appointed officials Educational Fund National Black Leadership $6,000.00 Corporate Sponsorship Commission on AIDS National Black Leadership $5,000.00 Corporate Sponsorship Commission on AIDS National Black Leadership $14,000.00 Corporate Sponsorship Commission on AIDS National Coalition for $40,000.00 Corporate Sponsorship Cancer National Coalition for $2,500.00 Corporate Sponsorship Cancer National Comprehensive $25,000.00 Corporate Sponsorship Cancer Network National Comprehensive $7,196.32 Educational Grants Cancer Network National Comprehensive $50,000.00 Educational Grants Cancer Network National Comprehensive $50,000.00 Educational Grants Cancer Network National Comprehensive ($1,824.00) Educational Grants Cancer Network, Inc. National Family Caregivers $30,000.00 Corporate Sponsorship Association National Foundation for $25,000.00 Corporate Sponsorship Celiac Awareness National Hispanic Council $30,000.00 Corporate Sponsorship on Aging National Kidney Foundation $500.00 Corporate Sponsorship National Minority Quality $20,000.00 Corporate Sponsorship forum Inc. National Minority Quality $5,000.00 Corporate Sponsorship forum Inc National Multiple Sclerosis $10,000.00 Corporate Sponsorship Society National Multiple Sclerosis $10,000.00 Corporate Sponsorship Society National Multiple Sclerosis $225,000.00 Corporate Sponsorship Society National Pancreas $5,000.00 Corporate Sponsorship Foundation National Pancreas $75,000.00 Charitable Donation Foundation National Pancreas $75,000.00 Educational Grants Foundation National Pancreas $6,000.00 Corporate Sponsorship Foundation National Pancreas $25,000.00 Corporate Sponsorship Foundation National Pancreas $200,000.00 Educational Grants Foundation National Pancreas $2,000.00 Corporate Sponsorship Foundation National Pancreas $1,000.00 Corporate Sponsorship Foundation National Pancreas $1,500.00 Corporate Sponsorship Foundation National Pancreas $2,500.00 Corporate Sponsorship Foundation National Pancreas $2,500.00 Corporate Sponsorship Foundation National Pancreas $2,500.00 Corporate Sponsorship Foundation National Pancreas $1,500.00 Corporate Sponsorship Foundation National Pancreas $6,000.00 Corporate Sponsorship Foundation National Pancreas $500.00 Corporate Sponsorship Foundation National Patient Advocate $65,000.00 Corporate Sponsorship Foundation Inc. National Psoriasis $30,000.00 Patient Support Foundation National Psoriasis $15,000.00 Corporate Sponsorship Foundation National Psoriasis $25,000.00 Corporate Sponsorship Foundation National Psoriasis $40,000.00 Educational Grants Foundation National Psoriasis $10,000.00 Corporate Sponsorship Foundation National Psoriasis $150,000.00 Corporate Sponsorship Foundation National Psoriasis $50,000.00 Corporate Sponsorship Foundation National Society for $50,000.00 Corporate Sponsorship Cutaneous Medicine National Society for $125,000.00 Corporate Sponsorship Cutaneous Medicine National Society for $135,000.00 Corporate Sponsorship Cutaneous Medicine Nationwide Childrens Hosp $7,500.00 Corporate Sponsorship Foundation Natl Commission On $20,000.00 Educational Grants Correctional Hlth Care Natl Committee for Quality $25,000.00 Corporate Sponsorship Assurance Natl Comprehensive Cancer $40,000.00 Charitable Donation Ntwrk Natl Comprehensive Cancer $25,000.00 Charitable Donation Ntwrk Natl Multiple Sclerosis $15,000.00 Corporate Sponsorship Socty Greater Illinois Chapter Nebraska Gut Club $600.00 Corporate Sponsorship Neuro Challenge Foundation $5,000.00 Corporate Sponsorship Inc. Neuropathy Action $2,500.00 Corporate Sponsorship Foundation New Jersey Association for $2,500.00 Educational Grants Biomedical Research New Mexico Parkinsons $3,000.00 Educational Grants Disease Coalition New York Academy of $2,500.00 Educational Grants Sciences New York State Rheumatology $15,000.00 Corporate Sponsorship Society New York Univ School of $10,000.00 Educational Grants Medicine New York Univ School of ($40,000.01) Fellowships or Medicine Scholarships New York Univ School of $10,000.00 Educational Grants Medicine Nicole Jarvis Md Parkinsons $1,000.00 Corporate Sponsorship Research Foundation Nl Communications Inc. $20,000.00 Educational Grants Nl Communications Inc. $20,000.00 Educational Grants Nl Communications Inc. $50,000.00 Educational Grants Nl Communications Inc. $15,000.00 Educational Grants North American Ctr for $350,000.00 Educational Grants Continuing Med Education North American Ctr for $60,000.00 Educational Grants Continuing Med Education North American Ctr for $200,000.00 Educational Grants Continuing Med Education North American Ctr for $200,000.00 Educational Grants Continuing Med Education North American Ctr for $375,000.00 Educational Grants Continuing Med Education North American Ctr for $39,500.00 Educational Grants Continuing Med Education North American Ctr for $88,000.00 Educational Grants Continuing Med Education Northeast Business Group on $1,000.00 Corporate Sponsorship Health Northeast Business Group on $5,000.00 Corporate Sponsorship Health Northwest Arthritis and $120,000.00 Educational Grants Osteoporosis Institute Northwest Arthritis and $30,000.00 Educational Grants Osteoporosis Institute Northwest Kidney Centers $2,500.00 Corporate Sponsorship Northwest Kidney Centers $2,500.00 Corporate Sponsorship Northwest Parkinson's $4,500.00 Educational Grants Foundation Northwest Parkinson's $550.00 Corporate Sponsorship Foundation Northwestern University $40,000.00 Fellowships or Scholarships Northwestern University $40,000.00 Fellowships or Scholarships Northwestern University $3,000.00 Educational Grants Norton Healthcare $1,200.00 Corporate Sponsorship Foundation Novation LLC $25,000.00 Corporate Sponsorship Nyu Langone Medical Center $3,000.00 Corporate Sponsorship Ochsner Clinic Foundation $2,000.00 Corporate Sponsorship Ohio Association of $10,000.00 Corporate Sponsorship Rheumatology Ohio Gastroenterology $5,000.00 Corporate Sponsorship Society Oklahoma State Urological $10,000.00 Corporate Sponsorship Association Oncology Nursing Society $5,000.00 Educational Grants One Health Research $50,000.00 Charitable Donation Oregon Health And Science $3,000.00 Corporate Sponsorship University Oregon Health And Science $12,000.00 Educational Grants University Oregon Health And Science $5,000.00 Educational Grants University Oregon Health And Science $3,000.00 Corporate Sponsorship University Oregon State University $7,500.00 Corporate Sponsorship Foundation Orthopaedic Research $5,000.00 Educational Grants Society Pacific Dermatologic $10,000.00 Corporate Sponsorship Association Pacific Dermatologic $20,000.00 Corporate Sponsorship Association Pancreas Club The $10,000.00 Educational Grants Pancreatic Cancer Action $3,000.00 Corporate Sponsorship Network Pancreatic Cancer Action $3,000.00 Corporate Sponsorship Network Pancreatic Cancer Action $200,000.00 Corporate Sponsorship Network Park Nicollet Foundation $1,000.00 Corporate Sponsorship Parkinson Alliance Inc. $500.00 Corporate Sponsorship Parkinson Alliance Inc. $1,000.00 Corporate Sponsorship Parkinson And Movement $4,000.00 Corporate Sponsorship Disorder Alliance Parkinson Association of $2,500.00 Corporate Sponsorship Alabama Parkinson Association of $1,000.00 Corporate Sponsorship The Carolinas Parkinson Association of $8,000.00 Patient Support The Rockies Parkinson Council $1,000.00 Corporate Sponsorship Parkinson Foundation of $500.00 Corporate Sponsorship Oklahoma Parkinson Foundation of $1,500.00 Corporate Sponsorship Oklahoma Parkinson Foundation of The $5,000.00 Educational Grants National Capital Area Parkinson Foundation of The $2,500.00 Corporate Sponsorship National Capital Area Parkinson Foundation $5,000.00 Corporate Sponsorship Western Pennsylvania Parkinson Institute $25,000.00 Corporate Sponsorship Parkinson Society of $250.00 Corporate Sponsorship Greenville Area Parkinson Support Group of $2,000.00 Educational Grants Upstate NY Parkinson Voice Project $2,500.00 Corporate Sponsorship Parkinsons Action Network $1,000.00 Corporate Sponsorship Foundation Parkinsons Action Network $1,000.00 Corporate Sponsorship Foundation Parkinsons Action Network $2,500.00 Corporate Sponsorship Foundation Parkinsons Action Network $5,000.00 Corporate Sponsorship Foundation Parkinsons And Movement $2,000.00 Corporate Sponsorship Disorder Foundation Parkinson's Disease $50,000.00 Educational Grants Foundation Parkinsons Disease Research $1,000.00 Corporate Sponsorship Society Parkinson's Resources of $5,000.00 Patient Support Oregon Parkinson's Resources of $2,500.00 Corporate Sponsorship Oregon Partnership for A Drug-Free $50,000.00 Charitable Donation America Patient Access Network $3,000,000.00 Charitable Donation Foundation Patient Access Network $5,000,000.00 Charitable Donation Foundation Patient Access Network $5,000,000.00 Charitable Donation Foundation Patient Access Network $250,000.00 Charitable Donation Foundation Patient Access Network $387,500.00 Charitable Donation Foundation Patient Access Network $400,000.00 Charitable Donation Foundation Patient Access Network $500,000.00 Charitable Donation Foundation Patient Empowerment Network $9,000.00 Educational Grants Patient Empowerment Network $20,000.00 Patient Support Patient Empowerment Network $20,000.00 Educational Grants Patient Empowerment Network $35,000.00 Educational Grants Pediatric Endocrinology $5,000.00 Corporate Sponsorship Nursing Society Pediatric Ibd Foundation $15,000.00 Corporate Sponsorship Pediatric Specialists of $2,500.00 Corporate Sponsorship Virginia LLC Pennsylvania Biotechnology $3,000.00 Corporate Sponsorship Association Pennsylvania Prostate $5,000.00 Patient Support Cancer Coalition Pennsylvania Society of $15,000.00 Corporate Sponsorship Gastroenterology Pennsylvania State Univ $135,000.00 Educational Grants Pennsylvania State Univ $50,000.00 Educational Grants Pennsylvania State Univ ($3,067.00) Educational Grants Pennsylvania State Univ $50,000.00 Educational Grants Pennsylvania State Univ ($9,660.00) Educational Grants Pennsylvania State Univ ($32,062.00) Educational Grants Pennsylvania State Univ $75,000.00 Educational Grants Pennsylvania State Univ $75,000.00 Educational Grants Philadelphia Dermatological $75,000.00 Corporate Sponsorship Society Philadelphia Fight $5,000.00 Corporate Sponsorship Philadelphia Fight $2,500.00 Corporate Sponsorship Phmcy Quality Alliance $10,000.00 Educational Grants Phrmct Care Mgmt Asoc $75,000.00 Corporate Sponsorship Phrmct Care Mgmt Asoc $60,000.00 Corporate Sponsorship Phrmct Care Mgmt Asoc $85,000.00 Corporate Sponsorship Phrmct Care Mgmt Asoc $70,000.00 Corporate Sponsorship Physicians' Education $40,000.00 Educational Grants Resource, LLC Physicians' Education $85,000.00 Educational Grants Resource, LLC Pikes Peak Habitat for $2,500.00 Charitable Donation Humanity Premier Cares Foundation $5,000.00 Corporate Sponsorship Premier Cares Foundation $5,000.00 Corporate Sponsorship President and Fellows of $3,000.00 Educational Grants Harvard College President and Fellows of $5,000.00 Educational Grants Harvard College Prevent Cancer Foundation $25,000.00 Corporate Sponsorship Prevent Cancer Foundation $10,000.00 Corporate Sponsorship Prevent Cancer Foundation $75,000.00 Corporate Sponsorship Prime Education, Inc. $198,011.00 Educational Grants Prime Education, Inc. $400,000.00 Educational Grants Project Inform Inc. $75,000.00 Patient Support Project Inform Inc. $75,000.00 Charitable Donation Prostate Cancer Education $2,500.00 Corporate Sponsorship Council Prostate Cancer Foundation $4,000.00 Corporate Sponsorship Chicago Prostate Cancer Research $25,000.00 Educational Grants Institute Prostate Cancer Research $10,000.00 Corporate Sponsorship Institute Prostate Health Education $15,000.00 Educational Grants Network, Inc. Prostate Health Education $15,000.00 Educational Grants Network, Inc. Prostate Health $5,000.00 Corporate Sponsorship International Prostate Health $5,000.00 Corporate Sponsorship International Protein Society $1,500.00 Educational Grants Puerto Rico Academy of $5,000.00 Corporate Sponsorship Family Physician Puerto Rico Community $5,000.00 Educational Grants Network for Clinical Research On Aids Inc. Puerto Rico $20,000.00 Educational Grants Gastroenterology Association Puerto Rico $10,000.00 Educational Grants Gastroenterology Association Purdue University $125,000.00 Educational Grants Purdue University $200,000.00 Educational Grants Purdue University $300,000.00 Educational Grants PVI Peerview Institute for $100,000.00 Educational Grants Medical Education PVI Peerview Institute for ($207.00) Educational Grants Medical Education Quinsigamond Community $500.00 Charitable Donation College Rectors And Visitors of The $3,000.00 Educational Grants University of Virginia Regents of The University $40,000.00 Fellowships or of California Scholarships Regents of The University $25,000.00 Educational Grants of California Regents of The University $5,000.00 Educational Grants of California Regents of The University $3,500.00 Educational Grants of California Regents of The University $5,000.00 Educational Grants of California Regents of The University $4,000.00 Educational Grants of California Regents of The University $10,000.00 Educational Grants of California Regents of The University $2,000.00 Educational Grants of Michigan Regents of The University $10,000.00 Educational Grants of Michigan Regents of The University $10,000.00 Corporate Sponsorship of Michigan Regents University of $40,000.00 Fellowships or California Los Angeles Scholarships Regents University of $10,000.00 Educational Grants California Los Angeles Regents University of $40,000.00 Fellowships or California Los Angeles Scholarships Regents University of $5,000.00 Educational Grants California Los Angeles Respiratory Health $3,500.00 Corporate Sponsorship Association of Metropolitan Chicago Respiratory Health $4,050.00 Corporate Sponsorship Association of Metropolitan Chicago Rheumatism Society of The $15,000.00 Corporate Sponsorship District of Columbia Rheumatism Society of The $5,000.00 Corporate Sponsorship District of Columbia Rheumatology Alliance of $25,000.00 Corporate Sponsorship Louisiana Rheumatology Nurses Society $29,700.00 Corporate Sponsorship Rhode Island Pharmacy $600.00 Corporate Sponsorship Association Riverside Medical Clinic $7,500.00 Patient Support Charitable Foundation Robert Michael Educational $236,065.00 Educational Grants Institute LLC Robert Michael Educational $90,000.00 Educational Grants Institute LLC Robert Michael Educational $275,000.00 Educational Grants Institute LLC Robert Michael Educational $90,000.00 Educational Grants Institute LLC Rock Hlth Inc. $15,000.00 Corporate Sponsorship Rush University Medical $15,000.00 Educational Grants Center Rush University Medical $5,000.00 Educational Grants Center Rutgers University $1,250.00 Charitable Donation Foundation Rutgers, The State $60,000.00 Educational Grants University of New Jersey Rutgers, The State $25,000.00 Educational Grants University of New Jersey Rutgers, The State $60,000.00 Educational Grants University of New Jersey Rutgers, The State $25,000.00 Educational Grants University of New Jersey Safety Pharmacology Society $5,000.00 Educational Grants Saint Francis Hospital And $15,000.00 Educational Grants Medical Center Saint Louis University $50,000.00 Corporate Sponsorship Hospital Scientists Center for $2,500.00 Educational Grants Animal Welfare Scott And White Healthcare $300.00 Corporate Sponsorship Foundation Scripps Health $75,000.00 Educational Grants Scripps Research Institute $2,000.00 Educational Grants Scripps Research Institute $2,000.00 Educational Grants Sexual Medicine Society of $25,000.00 Educational Grants North America Sexual Medicine Society of $225,000.00 Corporate Sponsorship North America Shanti Project Inc. $20,000.00 Patient Support Smart Ride The $25,000.00 Corporate Sponsorship Sociedad Dermatologica De $20,000.00 Corporate Sponsorship Puerto Rico Sociedad Dermatologica De $10,000.00 Corporate Sponsorship Puerto Rico Sociedad Endocrinologia $10,000.00 Corporate Sponsorship Metabolismo Y Diabetes Del Sur Sociedad Puertorriquena De $15,000.00 Corporate Sponsorship Endocronologia Y Diabetologia Sociedad Puertorriquena De $10,000.00 Corporate Sponsorship Endocronologia Y Diabetologia Sociedad Puertorriquena De $5,000.00 Corporate Sponsorship Pediatria Sociedad Puertorriquena De $5,000.00 Corporate Sponsorship Pediatria Sociedad Puertorriquena De $5,000.00 Corporate Sponsorship Pediatria Society for Investigative $20,000.00 Educational Grants Dermatology Society for Leukocyte $1,500.00 Educational Grants Biology Society for Mucosal $16,398.00 Corporate Sponsorship Immunology Society for Neuroscience ($2,500.00) Educational Grants Society for Neuroscience $1,000.00 Educational Grants Society for Neuroscience $2,000.00 Educational Grants Society for Translational $15,000.00 Educational Grants Oncology Society of Dermatology $20,000.00 Corporate Sponsorship Physician Assistants Society of Dermatology $45,000.00 Corporate Sponsorship Physician Assistants Society of Dermatology $30,000.00 Corporate Sponsorship Physician Assistants Society of Gastroenterology $25,000.00 Educational Grants Nurses & Associates Society of Neuro Oncology $16,000.00 Corporate Sponsorship Society of Nuclear Medicine $4,000.00 Corporate Sponsorship Society of Toxicologic $15,000.00 Corporate Sponsorship Pathology Socty of Toxicology $2,000.00 Fellowships or Scholarships Somos El Futuro, Inc. $5,000.00 Corporate Sponsorship South Carolina Alliance of $5,000.00 Corporate Sponsorship Health Plans Southern Illinois ($711.12) Fellowships or University Scholarships Spondylitis Association of $40,000.00 Educational Grants America Spondylitis Association of $19,000.00 Educational Grants America Spondyloarthritis Research $25,000.00 Corporate Sponsorship And Treatment Network Spartan St. Christophers Foundation $5,000.00 Corporate Sponsorship for Children St. Lukes Regional Medical $10,000.00 Corporate Sponsorship Center St. Luke's-Roosevelt $5,000.00 Educational Grants Hospital Center Take A Breather Foundation $10,000.00 Corporate Sponsorship Tampa Bay Latin American $3,000.00 Corporate Sponsorship Medical Society Team Fox North Texas $500.00 Corporate Sponsorship Tennessee Rheumatology $7,500.00 Corporate Sponsorship Society Teratology Society $2,000.00 Educational Grants Test Positive Awareness $30,000.00 Corporate Sponsorship Network Texas Liver Inst The $30,000.00 Corporate Sponsorship Texas Osteopathic Medical $1,000.00 Corporate Sponsorship Association Texas Urological Society $6,000.00 Corporate Sponsorship Thomas Jefferson University $500,000.00 Educational Grants Medical College Thomas Jefferson University $10,000.00 Educational Grants Medical College Thomas Jefferson University $2,500.00 Corporate Sponsorship Medical College Torrington Area Parkinsons $500.00 Corporate Sponsorship Support Group Trustees of The University $40,000.00 Educational Grants of Pennsylvania Twine Clinical Consulting $411,950.00 Educational Grants LLC Ultimate Med Academy Med ($3,550.00) Educational Grants Learning Grp LLC United States Adult Cystic $7,500.00 Educational Grants Fibrosis Association Univ Hlth Srvc At Stony $20,000.00 Educational Grants Point Inc. Univ of Colorado Denver $2,500.00 Educational Grants School of Medicine Universidad Central Del $10,000.00 Educational Grants Caribe, Inc. University At Buffalo $1,250.00 Charitable Donation Foundation Inc. University of Alabama At $40,000.00 Fellowships or Birmingham Scholarships University of California-- $10,000.00 Educational Grants San Francisco University of California $30,000.00 Educational Grants Berkeley University of California $5,000.00 Educational Grants Irvine University of Chicago ($75,000.00) Educational Grants University of Chicago $65,000.00 Educational Grants University of Chicago $5,000.00 Educational Grants University of Chicago $7,000.00 Educational Grants University of Chicago $157,000.00 Educational Grants University of Chicago ($4,249.00) Educational Grants University of Chicago ($3,746.25) Educational Grants University of Chicago $1,000.00 Corporate Sponsorship University of Chicago $400,000.00 Educational Grants University of Chicago $1,500.00 Educational Grants University of Chicago ($13,195.00) Educational Grants University of Cincinnati $60,000.00 Educational Grants University of Cincinnati ($25,000.00) Educational Grants University of Cincinnati ($50,000.00) Educational Grants University of Cincinnati ($25,000.00) Educational Grants University of Cincinnati $2,081,222.00 Educational Grants University of Cincinnati $5,000.00 Educational Grants University of Cincinnati $2,000.00 Educational Grants University of Cincinnati $30,000.00 Educational Grants University of Cincinnati $8,000.00 Educational Grants University of Cincinnati $75,000.00 Educational Grants University of Connecticut $40,000.00 Fellowships or Scholarships University of Connecticut $12,000.00 Fellowships or Scholarships University of Florida $125,875.00 Educational Grants University of Florida ($5,709.00) Educational Grants University of Florida $1,500.00 Educational Grants Foundation Inc. University of Florida $40,000.00 Fellowships or Foundation Inc. Scholarships University of Illinois $12,000.00 Corporate Sponsorship University of Illinois $12,000.00 Corporate Sponsorship University of Louisville $15,000.00 Educational Grants Research Foundation, Inc. University of Maryland $5,500.00 Educational Grants University of Maryland $10,000.00 Educational Grants Baltimore University of Maryland $1,250.00 Charitable Donation Baltimore Foundation University of Massachusetts $2,500.00 Charitable Donation Med School University of Miami $25,000.00 Educational Grants University of Miami $10,000.00 Educational Grants University of Miami $50,000.00 Corporate Sponsorship Department of Dermatology University of Minnesota $1,250.00 Charitable Donation University of Minnesota $1,250.00 Charitable Donation University of Minnesota $1,250.00 Charitable Donation University of Missouri Dept $500.00 Corporate Sponsorship of Neurology University of Nebraska Med $25,000.00 Educational Grants Ctr University of Nebraska Med $10,000.00 Educational Grants Ctr University of Nebraska Med $50,000.00 Educational Grants Ctr University of Nebraska Med $5,000.00 Educational Grants Ctr University of North $40,000.00 Fellowships or Carolina At Chapel Hill Scholarships University of North $2,500.00 Educational Grants Carolina At Chapel Hill University of Pittsburgh $10,000.00 Educational Grants University of Pittsburgh $10,000.00 Educational Grants University of Pittsburgh $2,250.00 Educational Grants University of Pittsburgh $2,000.00 Educational Grants University of Pittsburgh $20,000.00 Educational Grants University of Rochester, $40,000.00 Fellowships or Center for Experiential Scholarships Learning University of South Florida $50,000.00 Educational Grants Hlth Professions Conferencing Corporation University of South Florida $10,000.00 Corporate Sponsorship Hlth Professions Conferencing Corporation University of South Florida $10,000.00 Corporate Sponsorship Hlth Professions Conferencing Corporation University of Southern $1,500.00 Educational Grants California University of Southern ($17,026.00) Educational Grants California University of Southern ($2,974.00) Educational Grants California University of Southern $71,800.00 Fellowships or California Scholarships University of Texas Hlth $2,500.00 Educational Grants Scnc Ctr At San Antonio University of Texas Hlth $135,000.00 Corporate Sponsorship Scnc Ctr At San Antonio University of Texas Hlth $50,000.00 Educational Grants Scnc Ctr At San Antonio University of Texas ($100,000.00) Educational Grants Southwestern Med Ctr University of The $1,500.00 Corporate Sponsorship Philippines Med Alumni Socty In America Nevada University of Toledo $2,000.00 Educational Grants University of Utah $40,000.00 Fellowships or Scholarships Urological Association of $10,000.00 Corporate Sponsorship Physician Assistants Urological Association of $25,000.00 Corporate Sponsorship Physician Assistants Urology Center of Colorado $7,500.00 Corporate Sponsorship Foundation US Pain Foundation, Inc. $25,000.00 Corporate Sponsorship US Pain Foundation, Inc. $30,000.00 Corporate Sponsorship US Pain Foundation, Inc. $80,000.00 Corporate Sponsorship Us Too International Inc. $5,000.00 Corporate Sponsorship Us Too International Inc. $5,000.00 Corporate Sponsorship Us Too International Inc. $25,000.00 Corporate Sponsorship USMD Health System $10,000.00 Corporate Sponsorship Van Andel Research $5,000.00 Educational Grants Institute Vanderbilt University Med $25,000.00 Fellowships or Ctr Scholarships Vanderbilt University $2,500.00 Educational Grants Medical Center Vindico Medical Education $146,000.00 Educational Grants LLC Vindico Medical Education $500,000.00 Educational Grants LLC Vindico Medical Education $35,000.00 Educational Grants LLC Virginia Commonwealth Univ $1,250.00 Charitable Donation School of Medicine Virginia Commonwealth Univ $1,000.00 Corporate Sponsorship School of Medicine Wall Las Memorias $25,000.00 Corporate Sponsorship Washington State Urology $7,500.00 Corporate Sponsorship Society Washington University $5,000.00 Educational Grants Washington University ($1,248.95) Fellowships or Scholarships WC Research Inc. $8,500.00 Corporate Sponsorship Webmd Global LLC $430,600.00 Educational Grants Webmd Global LLC $1,165,500.00 Educational Grants Well Project Inc. $20,000.00 Charitable Donation Western States Phmcy $10,000.00 Corporate Sponsorship Conference for Phmcy Residents Fellowships & Preceptors Wheaton Franciscan $500.00 Corporate Sponsorship Healthcare Foundation Wisconsin Academy of Phys $4,000.00 Corporate Sponsorship Assistants Wisconsin Collaborative for $2,500.00 Corporate Sponsorship Healthcare Quality Wisconsin Dairyland Chapter $1,910.00 Corporate Sponsorship of HIMSS Wisconsin Medical Society $450.00 Corporate Sponsorship Wisconsin Rheumatology $5,000.00 Corporate Sponsorship Association Wishes And Dreams for $2,500.00 Corporate Sponsorship Cystic Fibrosis Wj Weiser And Associates $20,000.00 Corporate Sponsorship Wj Weiser And Associates $10,000.00 Corporate Sponsorship World Parkinson Coalition $15,000.00 Educational Grants Inc. World Parkinson Coalition $207,000.00 Corporate Sponsorship Inc. Yale University ($10,000.00) Educational Grants Yale University $25,000.00 Educational Grants Yale University $2,500.00 Educational Grants Young Survival Coalition $30,000.00 Corporate Sponsorship Zebrafish Disease Models $10,000.00 Educational Grants Society Zero The End of Prostate $10,000.00 Corporate Sponsorship Cancer Zero The End of Prostate $250,000.00 Corporate Sponsorship Cancer Zero The End of Prostate $15,000.00 Corporate Sponsorship Cancer Zero The End of Prostate $2,500.00 Corporate Sponsorship Cancer ------------------------------------------------------------------------ Grants Donations Report--2016 (Parentheses represent refunds of previously disclosed payments) Report as of 3/31/2017 ------------------------------------------------------------------------ Recipient Payment Amount Purpose ------------------------------------------------------------------------ 50 Hoops $10,000.00 Educational Grants A And R Educational Grp LLC $4,000.00 Corporate Sponsorship A Runners Love $5,000.00 Corporate Sponsorship AAALAC International $5,000.00 Educational Grants Academy of Managed Care $25,000.00 Corporate Sponsorship Phmcy Academy of Managed Care $25,000.00 Corporate Sponsorship Phmcy Academy of Managed Care $18,000.00 Corporate Sponsorship Phmcy Academy of Managed Care $40,000.00 Corporate Sponsorship Phmcy Academy of Managed Care $50,000.00 Corporate Sponsorship Phmcy Advances in Cosmetic And $75,000.00 Corporate Sponsorship Med Dermatology Inc. Advances in Cosmetic And $75,000.00 Corporate Sponsorship Med Dermatology Inc. Advances in Cosmetic And $100,000.00 Corporate Sponsorship Med Dermatology Inc. Adventist Hlth System-- $15,000.00 Corporate Sponsorship Sunbelt Inc. Adventist Hlth System-- $15,000.00 Corporate Sponsorship Sunbelt Inc. Advocate Hlth And Hospitals $2,000.00 Educational Grants Corporation Advocate Hlth And Hospitals $2,500.00 Educational Grants Corporation Aesthetic Dermatology $25,000.00 Corporate Sponsorship Symposia AIDS Action Committee $5,000.00 Corporate Sponsorship Aids Drug Assistance $5,000.00 Charitable Donations Programs Advocacy Asoc AIDS Foundation of Chicago $7,500.00 Corporate Sponsorship AIDS Foundation of Chicago $7,500.00 Corporate Sponsorship AIDS Foundation of Chicago ($7,500.00) Corporate Sponsorship AIDS Foundation of Chicago $75,000.00 Charitable Donations AIDS Institute $50,000.00 Corporate Sponsorship AIDS Institute $50,000.00 Corporate Sponsorship AIDS Institute $30,000.00 Corporate Sponsorship AIDS Institute $75,000.00 Corporate Sponsorship Alabama Asoc of Hlth Plans $3,000.00 Corporate Sponsorship Alabama Dermatology Socty $35,000.00 Corporate Sponsorship The Albany Med Colg $5,000.00 Educational Grants Albany Med Colg $10,000.00 Corporate Sponsorship Albert Einstein Colg of $10,000.00 Educational Grants Medicine Div of Dermatology Attending Asoc Albert Einstein College of $20,000.00 Educational Grants Medicine of Yeshiva University Albert Einstein College of $10,000.00 Educational Grants Medicine of Yeshiva University Albert Einstein College of $5,000.00 Educational Grants Medicine of Yeshiva University Albert Einstein College of $5,000.00 Educational Grants Medicine of Yeshiva University Albert Einstein Hlthcr $5,750.00 Corporate Sponsorship Ntwrk Alliance for Aging Research $30,000.00 Corporate Sponsorship Alliance for Aging Research $25,000.00 Corporate Sponsorship Alzheimers Asoc $15,000.00 Educational Grants Alzheimers Asoc $2,500.00 Corporate Sponsorship American Academy of $40,000.00 Charitable Donations Dermatology American Academy of $20,000.00 Corporate Sponsorship Dermatology American Academy of $13,550.00 Charitable Donations Dermatology American Academy of $40,000.00 Educational Grants Dermatology American Academy of ($60,000.00) Educational Grants Dermatology American Academy of $250,000.00 Corporate Sponsorship Dermatology American Academy of $50,000.00 Educational Grants Dermatology American Academy of $10,000.00 Charitable Donations Dermatology American Academy of Family $15,500.00 Educational Grants Phys American Academy of $9,290.00 Educational Grants Neurology Institute American Academy of $80,000.00 Corporate Sponsorship Neurology Institute American Academy of $20,720.70 Corporate Sponsorship Neurology Institute American Academy of $24,700.00 Educational Grants Neurology Institute American Academy of $10,010.00 Corporate Sponsorship Neurology Institute American Academy of $50,000.00 Fellowships and Neurology Institute Scholarships American Academy of $2,700.00 Corporate Sponsorship Neurology Institute American Academy of $22,616.70 Corporate Sponsorship Neurology Institute American Academy of $6,500.00 Corporate Sponsorship Ophthalmology AAO American Academy of $15,000.00 Corporate Sponsorship Ophthalmology AAO American Academy of Phys $10,000.00 Educational Grants Assistants American Assoc for Cancer $50,000.00 Educational Grants Research American Assoc for Cancer $20,000.00 Fellowships and Research Scholarships American Assoc for Cancer $10,000.00 Educational Grants Research American Assoc for Cancer $50,000.00 Educational Grants Research American Assoc for Cancer $10,000.00 Educational Grants Research American Assoc for Cancer $25,000.00 Charitable Donations Research American Assoc for Cancer $20,000.00 Educational Grants Research American Assoc for Cancer $10,000.00 Educational Grants Research American Assoc for Cancer $10,000.00 Educational Grants Research American Assoc for Cancer $15,000.00 Educational Grants Research American Assoc for Cancer $15,000.00 Educational Grants Research American Assoc for Cancer $15,000.00 Educational Grants Research American Assoc for Cancer $50,000.00 Educational Grants Research American Assoc for Cancer $15,000.00 Educational Grants Research American Assoc for Cancer $10,000.00 Educational Grants Research American Assoc for Lab $20,000.00 Charitable Donations Animal Scnc Fdtn American Assoc for The $85,000.00 Corporate Sponsorship Study of Liver Diseases American Assoc of Clinical $15,000.00 Educational Grants Endocrinologists New Jersey Chapter American Assoc of Clinical $25,000.00 Educational Grants Endocrinologists New Jersey Chapter American Assoc of Clinical $328,000.00 Corporate Sponsorship Endocrinologists New Jersey Chapter American Assoc of Phys of $10,000.00 Corporate Sponsorship Indian Origin Arkansas American Asosc of Phys of $5,000.00 Corporate Sponsorship Indian Origin Arkansas American Association for $500,000.00 Charitable Donations The Study of Liver Diseases (AASLD Foundation) American Association of $50,000.00 Corporate Sponsorship Pharmaceutical Scientists American Brain Tumor Asoc $7,500.00 Corporate Sponsorship American Brain Tumor Asoc $5,000.00 Corporate Sponsorship American Brain Tumor Asoc $5,000.00 Corporate Sponsorship American Brain Tumor Asoc $10,000.00 Educational Grants American Brain Tumor Asoc $7,000.00 Educational Grants American Cancer Society $5,000.00 Corporate Sponsorship American Cancer Society $2,500.00 Corporate Sponsorship Cancer Action Network American Cancer Society $25,000.00 Corporate Sponsorship Cancer Action Network American Cancer Society $2,500.00 Corporate Sponsorship Cancer Action Network American Cancer Society $2,500.00 Corporate Sponsorship Cancer Action Network American Cancer Society $2,500.00 Corporate Sponsorship Cancer Action Network American Cancer Society $5,000.00 Corporate Sponsorship Cancer Action Network American Cancer Society $3,500.00 Corporate Sponsorship Cancer Action Network American Cancer Society $1,000.00 Corporate Sponsorship Cancer Action Network American Cancer Society $7,000.00 Corporate Sponsorship Cancer Action Network American Cancer Society $5,000.00 Corporate Sponsorship Cancer Action Network American Chem Socty $2,500.00 Educational Grants American Chem Socty $2,500.00 Educational Grants American Chem Socty $2,500.00 Educational Grants American Chem Socty $1,000.00 Educational Grants American Childhood Cancer $2,500.00 Corporate Sponsorship Organization American Colg of Gastro $100,000.00 Corporate Sponsorship American Colg of Gastro $15,640.00 Corporate Sponsorship American Colg of Gastro $15,640.00 Corporate Sponsorship American Colg of Gastro $15,640.00 Corporate Sponsorship American Colg of Gastro $41,400.00 Corporate Sponsorship American Colg of Gastro $10,000.00 Educational Grants American Colg of Gastro $500,000.00 Corporate Sponsorship American Colg of Gastro $20,000.00 Corporate Sponsorship American Colg of Lab Animal $30,000.00 Charitable Donations Medicine American Colg of $30,000.00 Corporate Sponsorship Obstetricians And Gynecologists American Colg of $32,500.00 Corporate Sponsorship Obstetricians And Gynecologists American Colg of $2,500.00 Corporate Sponsorship Obstetricians And Gynecologists District 1 American Colg of Rheumlgy $2,000,000.00 Corporate Sponsorship Research And Education Fdtn American Colg of Rheumlgy $1,500,000.00 Corporate Sponsorship Research And Education Fdtn American Colg of Toxicology $1,000.00 Corporate Sponsorship American College of $50,000.00 Educational Grants Rheumatology American College of $75,000.00 Corporate Sponsorship Rheumatology American College of $95,000.00 Fellowships and Rheumatology Scholarships American College of $50,000.00 Educational Grants Rheumatology American College of $35,000.00 Educational Grants Rheumatology American College of $25,000.00 Educational Grants Rheumatology American Drug Utilization $20,000.00 Corporate Sponsorship Review Society Adurs American Drug Utilization $6,666.67 Corporate Sponsorship Review Society Adurs American Drug Utilization $6,666.67 Corporate Sponsorship Review Society Adurs American Drug Utilization $6,666.66 Corporate Sponsorship Review Society Adurs American Federation for Med $2,000.00 Educational Grants Research American Gastro Asoc Inst $50,000.00 Educational Grants American Gastro Asoc Inst $250,000.00 Educational Grants American Gastro Asoc Inst $33,300.00 Corporate Sponsorship American Kdny Fund $3,000.00 Corporate Sponsorship American Legion National $10,000.00 Corporate Sponsorship American Legion National $10,000.00 Corporate Sponsorship Headquarters American Liver Fdtn $2,500.00 Corporate Sponsorship American Liver Fdtn $246,500.00 Corporate Sponsorship American Liver Fdtn $10,000.00 Corporate Sponsorship American Liver Fdtn $2,500.00 Corporate Sponsorship American Liver Fdtn $2,500.00 Corporate Sponsorship American Liver Fdtn $5,000.00 Educational Grants American Liver Foundation $35,000.00 Corporate Sponsorship American Med Asoc Fdtn $20,000.00 Corporate Sponsorship American Med Grp Asoc $6,000.00 Corporate Sponsorship American Military Partner $5,000.00 Corporate Sponsorship Association American Neuro Asoc $5,000.00 Educational Grants American Neuro Asoc $25,000.00 Educational Grants American Osteopathic Colg $15,000.00 Corporate Sponsorship of Dermatology American Pancreatic Asoc $75,000.00 Educational Grants American Pancreatic Asoc $15,000.00 Patient Support American Pancreatic Asoc $50,000.00 Corporate Sponsorship American Parkinson Disease $5,000.00 Corporate Sponsorship Association Arizona Chapter American Parkinson Disease $500.00 Corporate Sponsorship Association Arizona Chapter American Parkinson Disease $1,000.00 Corporate Sponsorship Association Arizona Chapter American Parkinson Disease $3,500.00 Corporate Sponsorship Association Arizona Chapter American Parkinson Disease $500.00 Corporate Sponsorship Association Arizona Chapter American Parkinson Disease $1,500.00 Corporate Sponsorship Association Arizona Chapter American Parkinson Disease $2,500.00 Corporate Sponsorship Association Arizona Chapter American Parkinson Disease $500.00 Corporate Sponsorship Association Arizona Chapter American Parkinson Disease $5,000.00 Corporate Sponsorship Association Arizona Chapter American Parkinson Disease $3,000.00 Corporate Sponsorship Association Arizona Chapter American Parkinson Disease $1,000.00 Corporate Sponsorship Association Arizona Chapter American Parkinson Disease $55,000.00 Corporate Sponsorship Association Arizona Chapter American Pharmacists Asoc $3,000.00 Corporate Sponsorship American Pharmacists Asoc $13,500.00 Corporate Sponsorship American Red Cross of $10,000.00 Charitable Donations Greater Chicago American Red Cross of $50,000.00 Charitable Donations Greater Chicago American Society for $1,500.00 Educational Grants Experimental Neurotherapeutics American Socty for Matrix $1,000.00 Educational Grants Biology American Socty for Mens $10,000.00 Corporate Sponsorship Hlth The American Socty for $1,500.00 Educational Grants Pharmacology and Experimental Thrpt The Aspet American Socty for $5,750.00 Corporate Sponsorship Reproductive Medicine American Socty for $25,000.00 Educational Grants Reproductive Medicine American Socty for $50,000.00 Corporate Sponsorship Reproductive Medicine American Socty of $15,000.00 Corporate Sponsorship Anesthesiologists American Socty of Clinical $20,000.00 Educational Grants Oncology American Socty of $52,500.00 Corporate Sponsorship Hematology American Socty of $10,000.00 Educational Grants Hematology American Socty of $40,000.00 Educational Grants Hematology American Socty of $60,000.00 Corporate Sponsorship Hematology American Socty of $10,000.00 Charitable Donations Hematology American Socty of $50,000.00 Educational Grants Hematology American Socty of Nphro $40,000.00 Corporate Sponsorship American Socty of Nphro $8,700.00 Corporate Sponsorship American Thyroid Asoc Inc. $35,000.00 Educational Grants American Thyroid Asoc Inc. $10,000.00 Corporate Sponsorship American Urological Asoc. $50,000.00 Educational Grants Education and Research Inc. American Urological Asoc. $40,000.00 Corporate Sponsorship Education and Research Inc. American Urological Asoc. $25,000.00 Corporate Sponsorship Education and Research Inc. American Urological Asoc. $50,000.00 Charitable Donations Education and Research Inc. American Urological Asoc. $20,000.00 Educational Grants Education and Research Inc. American Urological Asoc. $75,000.00 Educational Grants Education and Research Inc. American Urological Asoc. $5,000.00 Corporate Sponsorship Fdtn American Urological Asoc $10,000.00 Charitable Donations Fdtn American Urological Asoc $6,000.00 Corporate Sponsorship Inc. North Ctrl Section American Urological Asoc $6,000.00 Corporate Sponsorship Inc. Southeast Section American Urological Asoc $10,000.00 Corporate Sponsorship Inc. Western Section American Urological Asoc $6,000.00 Corporate Sponsorship South Ctrl Section Americans for Med Progress $100,000.00 Charitable Donations Americares Foundation, Inc. $10,000.00 Charitable Donations Americares Foundation, Inc. $25,000.00 Charitable Donations Angel Fdtn $5,000.00 Corporate Sponsorship Annenberg Center for Health $750,000.00 Educational Grants Sciences at Eisenhower Annenberg Center for Health $90,000.00 Educational Grants Sciences at Eisenhower Annenberg Center for Health $65,000.00 Educational Grants Sciences at Eisenhower Annenberg Center for Health $25,000.00 Educational Grants Sciences at Eisenhower Annenberg Center for Health $85,000.00 Educational Grants Sciences at Eisenhower Annenberg Center for Health $350,000.00 Educational Grants Sciences at Eisenhower Annenberg Center for Health $75,000.00 Educational Grants Sciences at Eisenhower Annenberg Center for Health $500,000.00 Educational Grants Sciences at Eisenhower Annenberg Center for Health $25,000.00 Educational Grants Sciences at Eisenhower Annenberg Center for Health $500,000.00 Educational Grants Sciences at Eisenhower Annenberg Center for Health $200,000.00 Educational Grants Sciences at Eisenhower Annenberg Center for Health $75,000.00 Educational Grants Sciences at Eisenhower Arkansas State Rheumlgy $10,000.00 Corporate Sponsorship Asoc Arthritis Foundation $1,000.00 Educational Grants Arthritis Foundation $35,000.00 Corporate Sponsorship Arthritis Foundation $35,000.00 Educational Grants Arthritis Foundation $22,500.00 Educational Grants Arthritis Foundation $30,000.00 Corporate Sponsorship Arthritis Foundation $20,000.00 Corporate Sponsorship Arthritis Foundation $30,000.00 Corporate Sponsorship Arthritis Foundation $10,000.00 Corporate Sponsorship Arthritis Foundation $15,000.00 Educational Grants Arthritis Foundation $1,500.00 Corporate Sponsorship Arthritis Foundation $25,000.00 Corporate Sponsorship Arthritis Foundation $2,500.00 Corporate Sponsorship Arthritis Foundation $5,000.00 Corporate Sponsorship Arthritis Foundation $10,000.00 Corporate Sponsorship Arthritis Foundation $25,000.00 Corporate Sponsorship Arthritis Foundation $2,500.00 Corporate Sponsorship Arthritis Foundation $20,000.00 Corporate Sponsorship Arthritis Foundation $40,000.00 Corporate Sponsorship Arthritis Foundation $30,000.00 Corporate Sponsorship Arthritis Foundation $35,000.00 Corporate Sponsorship Arthritis Foundation $25,000.00 Corporate Sponsorship Arthritis Foundation $300,000.00 Corporate Sponsorship Arthritis Foundation $259,000.00 Corporate Sponsorship Arthritis Foundation $250,000.00 Corporate Sponsorship Arthritis Foundation $300,000.00 Corporate Sponsorship Arthritis Foundation $175,000.00 Corporate Sponsorship Arthritis Patient Srvc $10,000.00 Charitable Donations Arthritis Patient Srvc $15,000.00 Educational Grants Arthritis Patient Srvc $40,000.00 Educational Grants Asco Cancer Fdtn $100,000.00 Charitable Donations Asco Cancer Fdtn $60,000.00 Fellowships and Scholarships Asco Cancer Fdtn $30,500.00 Corporate Sponsorship Asco Cancer Fdtn $28,000.00 Educational Grants Asco Cancer Fdtn $28,000.00 Educational Grants ASCO Cancer Fdtn $28,000.00 Educational Grants ASCO Cancer Fdtn $5,000.00 Educational Grants ASCO Cancer Fdtn $25,000.00 Educational Grants Asoc De Enfermeria $6,000.00 Corporate Sponsorship Oncologica Y Hematologica De Puerto Rico Inc. Asoc De Reumatologos De $30,000.00 Corporate Sponsorship Puerto Rico Asoc Latina De Asistencia Y $1,000.00 Educational Grants Prevencion Del Cancer De Mama Asoc of Univ Tech Managers $5,000.00 Corporate Sponsorship Asociacion De Salud Publica $5,000.00 Educational Grants De Puerto Rico Aspen Cancer Conference $7,500.00 Educational Grants Inc. Association of Women in $40,000.00 Corporate Sponsorship Rheumatology Association of Women in $40,000.00 Corporate Sponsorship Rheumatology Atlanta Dermatological Asoc $10,000.00 Corporate Sponsorship Autoimmune Advocacy $2,500.00 Corporate Sponsorship Alliance Baehr Challenge Ltd $2,500.00 Corporate Sponsorship Balm In Gilead Inc. $75,000.00 Corporate Sponsorship Baylor Colg Medicine Inf $100,000.00 Fellowships and Dis Scholarships Baylor Colg Medicine Inf $3,500.00 Educational Grants Dis Baylor Hlth Care System $50,000.00 Fellowships and Fdtn Scholarships Baylor Scott And White $20,000.00 Educational Grants Health Baylor Univ Med Ctr $25,000.00 Educational Grants Baylor Univ Med Ctr $25,000.00 Educational Grants Baylor Univ Med Ctr $20,000.00 Educational Grants Beth Israel Deaconess Med $40,000.00 Fellowships and Ctr Scholarships Beth Israel Deaconess Med $30,000.00 Fellowships and Ctr Scholarships Beth Israel Deaconess Med $27,000.00 Fellowships and Ctr Scholarships Beth Israel Deaconess Med $7,500.00 Educational Grants Ctr Beth Israel Deaconess Med ($592.19) Fellowships and Ctr Scholarships Bexar County Physician $2,500.00 Corporate Sponsorship Assistant Society Bioconnections LLC $30,000.00 Corporate Sponsorship Black Hills Arthritis Asoc $2,200.00 Educational Grants Boomer Esiason Fdtn $25,000.00 Corporate Sponsorship Boomer Esiason Fdtn $400,000.00 Corporate Sponsorship Borland Groover Fdtn $500.00 Corporate Sponsorship Boston Center for $5,000.00 Corporate Sponsorship Independent Living Boston Socty Inc. $4,000.00 Corporate Sponsorship Boston Socty Inc. $4,000.00 Corporate Sponsorship Boston Univ Medcn Psychtry $40,000.00 Fellowships and Scholarships Boston Univ Medcn Psychtry $45,000.00 Educational Grants Boston Univ Medcn Psychtry $10,000.00 Educational Grants Boston Univ Medcn Psychtry $100,000.00 Educational Grants Boston Univ Medcn Psychtry ($2,482.00) Educational Grants Boston Univ Medcn Psychtry $40,000.00 Fellowships and Scholarships Boston Univ Medcn Psychtry $85,000.00 Educational Grants Brian Grant Fdtn The $25,000.00 Corporate Sponsorship Brian Grant Fdtn The $30,000.00 Educational Grants Brian Grant Fdtn The $10,000.00 Corporate Sponsorship Brigham And Women's $250,000.00 Educational Grants Hospital, Inc. Brigham And Women's $40,000.00 Fellowships and Hospital, Inc. Scholarships Bucks Montgomery Counties $1,000.00 Corporate Sponsorship Oncology Nursing Socty Business Hlth Coalition $3,300.00 Corporate Sponsorship Fdtn California Assn Physcn Grps $20,000.00 Corporate Sponsorship Fnd California Assn Physcn Grps $10,000.00 Corporate Sponsorship Fnd California Chronic Care $35,000.00 Corporate Sponsorship Coalition California Inst of Tech $5,000.00 Fellowships and Scholarships California Issues forum $15,000.00 Corporate Sponsorship California Life Sciences $3,000.00 Corporate Sponsorship Association California Life Sciences $5,000.00 Corporate Sponsorship Association California Life Sciences $1,500.00 Corporate Sponsorship Association California Pacific Med Ctr $2,000.00 Corporate Sponsorship Fdtn California Rheumlgy $3,000.00 Corporate Sponsorship Alliance California Socty of $10,000.00 Corporate Sponsorship Dermatology and Dermatology Surgry Cancer And Leukemia Grp B $30,000.00 Educational Grants Fdtn Cancer Awareness of Nevada $1,000.00 Corporate Sponsorship Cancer Care $10,000.00 Educational Grants Cancer Care $25,000.00 Educational Grants Cancer Care $50,000.00 Charitable Donations Cancer Care $20,000.00 Educational Grants Cancer Care $20,000.00 Educational Grants Cancer Care $10,000.00 Educational Grants Cancer Care $10,000.00 Educational Grants Cancer Care $100,000.00 Corporate Sponsorship Cancer Fdtn for New Mexico $2,500.00 Corporate Sponsorship Cancer Molecular Thrpt $1,500.00 Educational Grants Cancer Research Inst $7,500.00 Educational Grants Cancer Support Community $50,000.00 Corporate Sponsorship Cancer Wellness Center $2,500.00 Corporate Sponsorship Carden Jennings Publishing $15,000.00 Corporate Sponsorship Carden Jennings Publishing $5,000.00 Corporate Sponsorship Caribe Gyn $5,000.00 Corporate Sponsorship Caring Ambassadors Program $35,000.00 Corporate Sponsorship Caring Ambassadors Program $200,000.00 Charitable Donations Caring Ambassadors Program $2,500.00 Corporate Sponsorship Cascade AIDS Project $5,000.00 Corporate Sponsorship CE Outcomes LLC $96,770.00 Educational Grants Cedars--Sinai Med Ctr $10,000.00 Educational Grants Cedars--Sinai Med Ctr $40,000.00 Fellowships and Scholarships Center for Healthcare $5,000.00 Corporate Sponsorship Innovation Central Brain Tumor $20,000.00 Educational Grants Registry of The United States Chesapeake Uro Asoc $5,500.00 Corporate Sponsorship Chesapeake Uro Asoc $7,500.00 Corporate Sponsorship Chicago Council On Scnc and $20,000.00 Corporate Sponsorship Technologies Chicago Council On Scnc and $5,000.00 Corporate Sponsorship Technologies Childrens Digestive Hlth $85,000.00 Educational Grants and Nutrition Fdtn Childrens Digestive Hlth $40,000.00 Fellowships and and Nutrition Fdtn Scholarships Childrens Hosp Corporation $3,000.00 Corporate Sponsorship Chimp Haven $25,000.00 Charitable Donations Chris Elliott Fund $10,000.00 Charitable Donations Chronic Liver Disease Fdtn $75,000.00 Corporate Sponsorship Chronic Liver Disease Fdtn $500,000.00 Educational Grants Chronic Liver Disease Fdtn $25,000.00 Corporate Sponsorship Chronic Liver Disease Fdtn ($25,824.00) Educational Grants Chronic Lymphoytic Leukemia $15,000.00 Educational Grants Society Inc. Chronic Lymphoytic Leukemia $75,000.00 Educational Grants Society Inc. Chronic Lymphoytic Leukemia $50,000.00 Charitable Donations Society Inc. Chronic Lymphoytic Leukemia $65,000.00 Educational Grants Society Inc. Chronic Lymphoytic Leukemia $10,000.00 Educational Grants Society Inc. Cincinnati Childrens Hosp $40,000.00 Fellowships and Medic Scholarships Cincinnati Childrens Hosp $22,500.00 Corporate Sponsorship Medic Cleveland Clnc $65,000.00 Educational Grants Cleveland Clnc $57,000.00 Educational Grants Cleveland Clnc $5,000.00 Educational Grants Cleveland Clnc $50,000.00 Educational Grants-- Cleveland Clnc $5,000.00 Educational Grants Cleveland Clnc $4,000.00 Educational Grants Cleveland Clnc $5,000.00 Corporate Sponsorship Cleveland Clnc ($6,743.76) Educational Grants Cleveland Clnc $7,500.00 Educational Grants Cleveland Clnc ($6,093.50) Educational Grants Cleveland Clnc $5,000.00 Educational Grants Cleveland Clnc ($13,210.68) Educational Grants Cleveland Clnc $5,000.00 Educational Grants Cleveland Clnc Fdtn $50,000.00 Fellowships and Scholarships Cleveland Clnc Fdtn $40,000.00 Fellowships and Scholarships Clinical Care Optn LLC $175,000.00 Educational Grants Clinical Care Optn LLC $85,000.00 Educational Grants Clinical Care Optn LLC $75,000.00 Educational Grants Clinical Care Optn LLC $25,000.00 Educational Grants Clinical Care Optn LLC $173,615.00 Educational Grants Clinical Care Optn LLC $95,000.00 Educational Grants Clinical Care Optn LLC $347,520.00 Educational Grants Clinical Care Optn LLC $126,385.00 Educational Grants Clinical Care Optn LLC $50,000.00 Educational Grants Clinical Care Optn LLC $25,000.00 Educational Grants Clinical Care Optn LLC ($75,000.00) Educational Grants Clinical Care Optn LLC $75,000.00 Educational Grants Coalicion Para El Control $12,500.00 Corporate Sponsorship De Hepatitis En Puerto Rico Coalition for Prevention of $10,000.00 Corporate Sponsorship Colorectal Cancer In Puerto Rico Coalition On Positive $20,000.00 Corporate Sponsorship Health Empowerment Coalition On Positive $50,000.00 Charitable Donations Health Empowerment Coalition On Positive $10,000.00 Corporate Sponsorship Health Empowerment Cockerell Educational $15,000.00 Corporate Sponsorship Foundation Cold Spring Harbor Lab $5,000.00 Educational Grants Cold Spring Harbor Lab $1,500.00 Educational Grants Colegio Medicos--Cirujanos $10,000.00 Educational Grants Pr Collegium Internationale $10,000.00 Corporate Sponsorship Colorado Dietetic Asoc $1,500.00 Corporate Sponsorship Colorado Gerontological $5,000.00 Corporate Sponsorship Society Colorado Retina Asoc $15,000.00 Corporate Sponsorship Columbia Univ Med Ctr $15,000.00 Educational Grants Commty Fdtn $5,000.00 Corporate Sponsorship Commty Fdtn $5,000.00 Corporate Sponsorship Commty Liver Alliance $75,000.00 Educational Grants Commty Liver Alliance $5,000.00 Corporate Sponsorship Community Access National $2,500.00 Corporate Sponsorship Network Community Health $10,000.00 Corporate Sponsorship Community Initiatives $75,000.00 Corporate Sponsorship Community Initiatives $25,000.00 Corporate Sponsorship Community Initiatives $30,000.00 Corporate Sponsorship Community Liver Alliance $9,000.00 Corporate Sponsorship Community Liver Alliance $25,000.00 Corporate Sponsorship Community Liver Alliance $19,400.00 Corporate Sponsorship Complete Conference Mgmt $80,000.00 Educational Grants Connecticut Advanced Nurse $5,000.00 Corporate Sponsorship Practitioner Socty Connecticut Advocates for $500.00 Corporate Sponsorship Parkinsons Inc. Connecting To Cure Crohns $20,000.00 Corporate Sponsorship And Colitis Consortium of Multiple $150,000.00 Educational Grants Sclerosis Centers Consortium of Multiple $40,000.00 Educational Grants Sclerosis Centers Consortium of Multiple $85,000.00 Educational Grants Sclerosis Centers Consortium of Multiple $60,000.00 Educational Grants Sclerosis Centers Consortium of Multiple $25,000.00 Educational Grants Sclerosis Centers Consortium of Multiple $150,000.00 Educational Grants Sclerosis Centers Continuing Educational ($2,537.67) Educational Grants Alliance LLC Continuing Educational ($2,537.67) Educational Grants Alliance LLC Continuing Educational $375,000.00 Educational Grants Alliance LLC Continuing Educational $200,000.00 Educational Grants Alliance LLC Continuing Educational $375,000.00 Educational Grants Alliance LLC Continuing Educational $375,000.00 Educational Grants Alliance LLC Continuing Educational ($1,250.00) Educational Grants Alliance LLC Continuing Educational $75,000.00 Educational Grants Alliance LLC Continuing Educational $99,440.00 Educational Grants Alliance LLC Cornell Univ Weill Med Colg $1,500.00 Educational Grants Cornell Univ Weill Med Colg $15,000.00 Educational Grants Cornell Univ Weill Med Colg $3,000.00 Educational Grants Cornerstone Hlth Inc. $150,000.00 Educational Grants Cornerstone Hlth Inc. ($3,750.00) Educational Grants Cornerstone Hlth Inc. $90,000.00 Educational Grants Cornerstone Hlth Inc. $40,000.00 Educational Grants Cornerstone Hlth Inc. $90,000.00 Educational Grants Cornerstone Hlth Inc. $75,000.00 Educational Grants Creighton Univ $10,000.00 Educational Grants Critical Path Inst $25,000.00 Corporate Sponsorship Crohns And Colitis $165,000.00 Corporate Sponsorship Foundation Crohns And Colitis $110,000.00 Educational Grants Foundation of America Crohns And Colitis $100,000.00 Educational Grants Foundation of America Crohns And Colitis $100,000.00 Educational Grants Foundation of America Crohns And Colitis $100,000.00 Educational Grants Foundation of America Crohns and Colitis $100,000.00 Educational Grants Foundation of America Crohns and Colitis $31,000.00 Educational Grants Foundation of America Crohns and Colitis $25,000.00 Charitable Donations Foundation of America Crohns and Colitis $25,000.00 Charitable Donations Foundation of America Crohns and Colitis $1,500.00 Corporate Sponsorship Foundation of America Crohns and Colitis $800.00 Corporate Sponsorship Foundation of America Crohns and Colitis $2,500.00 Corporate Sponsorship Foundation of America Crohns and Colitis $10,000.00 Corporate Sponsorship Foundation of America Crohns and Colitis $10,250.00 Corporate Sponsorship Foundation of America Crohns and Colitis $50,000.00 Charitable Donations Foundation of America Crohns and Colitis $5,000.00 Corporate Sponsorship Foundation of America Crohns and Colitis $2,500.00 Corporate Sponsorship Foundation of America Crohns and Colitis $1,500.00 Corporate Sponsorship Foundation of America Crohns and Colitis $1,500.00 Corporate Sponsorship Foundation of America Crohns and Colitis $47,000.00 Corporate Sponsorship Foundation of America Crohns and Colitis $114,000.00 Corporate Sponsorship Foundation of America Crohns and Colitis $5,000.00 Corporate Sponsorship Foundation of America Crohns and Colitis $2,500.00 Corporate Sponsorship Foundation of America Crohns and Colitis $2,000.00 Corporate Sponsorship Foundation of America Crohns and Colitis $2,500.00 Corporate Sponsorship Foundation of America Crohns and Colitis $15,000.00 Corporate Sponsorship Foundation of America Crohns and Colitis $10,000.00 Corporate Sponsorship Foundation of America Crohns and Colitis $1,000.00 Corporate Sponsorship Foundation of America Crohns and Colitis $15,000.00 Corporate Sponsorship Foundation of America Crohns and Colitis $250,000.00 Educational Grants Foundation of America Crohns and Colitis $100,000.00 Fellowships and Foundation of America Scholarships Crohns and Colitis $400,000.00 Corporate Sponsorship Foundation of America Crohns and Colitis $80,000.00 Charitable Donations Foundation of America Crohns and Colitis $40,000.00 Corporate Sponsorship Foundation of America Crohns and Colitis $40,000.00 Educational Grants Foundation of America Ctrl Florida Phmcy Council $15,000.00 Educational Grants Inc. Ctrl Savannah River Area $1,000.00 Corporate Sponsorship Csra Parkinson Support Grp Curatio Cme Inst ($33,640.17) Educational Grants Cure CF $1,500.00 Corporate Sponsorship Curepsp Inc. $15,000.00 Educational Grants Cystic Fibrosis Fdtn-- $1,000.00 Corporate Sponsorship Albany Cystic Fibrosis Fdtn-- $750.00 Corporate Sponsorship Albany Cystic Fibrosis Fdtn-- $7,500.00 Corporate Sponsorship Albany Cystic Fibrosis Fdtn-- $1,750.00 Corporate Sponsorship Albany Cystic Fibrosis Fdtn-- $1,500.00 Corporate Sponsorship Albany Cystic Fibrosis Fdtn-- $1,000.00 Corporate Sponsorship Albany Cystic Fibrosis Fdtn-- $2,500.00 Corporate Sponsorship Albany Cystic Fibrosis Fdtn $4,000.00 Corporate Sponsorship Maryland Chapter Cystic Fibrosis Fdtn $5,750.00 Corporate Sponsorship Maryland Chapter Cystic Fibrosis Research $5,000.00 Corporate Sponsorship Fund Emilys Entourage Cystic Fibrosis Research $18,000.00 Corporate Sponsorship Inc. Cystic Fibrosis Research $7,000.00 Corporate Sponsorship Inc. Cystic Fibrosis Research $10,000.00 Corporate Sponsorship Inc. Cystic Fibrosis Research $10,000.00 Corporate Sponsorship Inc. Cystic Fibrosis Research $5,000.00 Corporate Sponsorship Inc. Cystic Fibrosis Research $3,000.00 Corporate Sponsorship Inc. Cystic Fibrosis Services $500.00 Corporate Sponsorship Cystic Fibrosis Services $500.00 Corporate Sponsorship Cystic Fibrosis Services $3,500.00 Corporate Sponsorship Cystic Fibrosis Services $1,000.00 Corporate Sponsorship Cystic Fibrosis Services $2,500.00 Corporate Sponsorship Cystic Fibrosis Services $2,000.00 Corporate Sponsorship Cystic Fibrosis Services $1,000.00 Corporate Sponsorship Cystic Fibrosis Services $2,000.00 Corporate Sponsorship Cystic Fibrosis Services $1,500.00 Corporate Sponsorship Cystic Fibrosis Services $1,750.00 Corporate Sponsorship Cystic Fibrosis Services $3,250.00 Corporate Sponsorship Cystic Fibrosis Services $1,750.00 Corporate Sponsorship Cystic Fibrosis Services $1,500.00 Corporate Sponsorship Cystic Fibrosis Services $1,000.00 Corporate Sponsorship Cystic Fibrosis Services $5,000.00 Corporate Sponsorship Cystic Fibrosis Services $7,500.00 Corporate Sponsorship Cystic Fibrosis Services $7,500.00 Corporate Sponsorship Cystic Fibrosis Services $2,500.00 Corporate Sponsorship Cystic Fibrosis Services $2,000.00 Corporate Sponsorship Cystic Fibrosis Services $5,000.00 Corporate Sponsorship Cystic Fibrosis Services $1,750.00 Corporate Sponsorship Cystic Fibrosis Services $5,000.00 Corporate Sponsorship Cystic Fibrosis Services $35,000.00 Corporate Sponsorship Cystic Fibrosis Services $15,000.00 Corporate Sponsorship Cystic Fibrosis Services $5,000.00 Corporate Sponsorship Cystic Fibrosis Services $1,000.00 Corporate Sponsorship Cystic Fibrosis Services $2,500.00 Corporate Sponsorship Cystic Fibrosis Services $2,000.00 Corporate Sponsorship Cystic Fibrosis Services $1,000.00 Corporate Sponsorship Cystic Fibrosis Services $1,000.00 Corporate Sponsorship Cystic Fibrosis Services $3,000.00 Corporate Sponsorship Cystic Fibrosis Services $3,500.00 Corporate Sponsorship Cystic Fibrosis Services $1,000.00 Corporate Sponsorship Cystic Fibrosis Services $5,000.00 Corporate Sponsorship Cystic Fibrosis Services $3,000.00 Corporate Sponsorship Cystic Fibrosis Services $2,500.00 Corporate Sponsorship Cystic Fibrosis Services $5,000.00 Corporate Sponsorship Cystic Fibrosis Services $3,000.00 Corporate Sponsorship Cystic Fibrosis Services $1,000.00 Corporate Sponsorship Cystic Fibrosis Services $3,500.00 Corporate Sponsorship Cystic Fibrosis Services $2,500.00 Corporate Sponsorship Cystic Fibrosis Services $1,000.00 Corporate Sponsorship Cystic Fibrosis Services $2,000.00 Corporate Sponsorship Cystic Fibrosis Services $5,000.00 Corporate Sponsorship Cystic Fibrosis Services $1,000.00 Corporate Sponsorship Cystic Fibrosis Services $2,500.00 Corporate Sponsorship Cystic Fibrosis Services $1,500.00 Corporate Sponsorship Cystic Fibrosis Services $10,000.00 Corporate Sponsorship Cystic Fibrosis Services $6,500.00 Corporate Sponsorship Cystic Fibrosis Services $5,000.00 Corporate Sponsorship Cystic Fibrosis Services $3,000.00 Corporate Sponsorship Cystic Fibrosis Services $1,750.00 Corporate Sponsorship Cystic Fibrosis Services $1,000.00 Corporate Sponsorship Cystic Fibrosis Services $35,000.00 Corporate Sponsorship Cystic Fibrosis Services $750,000.00 Corporate Sponsorship Cystic Fibrosis Services $5,000.00 Corporate Sponsorship Cystic Fibrosis Services $7,500.00 Corporate Sponsorship Cystic Fibrosis Services $7,500.00 Corporate Sponsorship Cystic Fibrosis Services $7,500.00 Corporate Sponsorship Cystic Fibrosis Services $6,500.00 Corporate Sponsorship Cystic Fibrosis Services $5,000.00 Corporate Sponsorship Cystic Fibrosis Services $5,000.00 Corporate Sponsorship Cystic Fibrosis Services $2,500.00 Corporate Sponsorship Cystic Fibrosis Services $1,000.00 Corporate Sponsorship Cystic Fibrosis Services $10,000.00 Corporate Sponsorship Cystic Fibrosis Services $1,500.00 Corporate Sponsorship Dallas fort Worth Business $5,000.00 Corporate Sponsorship Grp On Hlth Danville D Elegance Fdtn $2,500.00 Corporate Sponsorship Dava Oncology Lp $50,000.00 Corporate Sponsorship Dava Oncology Lp $150,000.00 Corporate Sponsorship David A Winston Health $5,500.00 Corporate Sponsorship Policy Davis Phinney Fdtn $30,000.00 Educational Grants Davis Phinney Fdtn $30,000.00 Educational Grants Davis Phinney Fdtn $20,000.00 Corporate Sponsorship Davis Phinney Fdtn $30,000.00 Educational Grants Davis Phinney Fdtn $60,000.00 Educational Grants Davis Phinney Fdtn $30,000.00 Educational Grants Davis Phinney Fdtn $40,000.00 Corporate Sponsorship Dermatology Education Fdtn $30,000.00 Corporate Sponsorship Dermatology Fdtn $135,000.00 Charitable Donations Dermatology Fdtn $50,000.00 Corporate Sponsorship Dermatology Nurses Asoc $10,000.00 Educational Grants Dermatology Nurses Asoc $25,850.00 Corporate Sponsorship Digestive Disease Week $55,000.00 Corporate Sponsorship Digestive Disease Week $55,000.00 Corporate Sponsorship Digestive Health Foundation $25,000.00 Corporate Sponsorship Digestive Health Physicians $100,000.00 Corporate Sponsorship Association Direct Relief $50,000.00 Charitable Donations East Hawaii IPA $8,500.00 Corporate Sponsorship Elsevier Inc. $40,000.00 Educational Grants Employers Hlth Colition $4,000.00 Corporate Sponsorship Inc. Endocrine Education Inc. $25,000.00 Educational Grants Endocrine Education Inc. $25,000.00 Educational Grants Engineering Conferences $1,500.00 Educational Grants International Enviormental Mutagen Socty $2,500.00 Corporate Sponsorship Enzyme Mechanism Conference $1,500.00 Educational Grants Epilepsy Association of $5,000.00 Corporate Sponsorship Central Florida Epilepsy Fnd of North- $20,000.00 Corporate Sponsorship Central Illinois Iowa and Nebraska Epilepsy Foundation of $5,000.00 Corporate Sponsorship Flordia Inc. Epilepsy Foundation of $18,000.00 Corporate Sponsorship Michigan Epilepsy Foundation of $20,000.00 Corporate Sponsorship Michigan Epilepsy Foundation of New $17,000.00 Corporate Sponsorship Jersey Escuela De Medicina De $20,000.00 Educational Grants Ponce Escuela De Medicina De $10,000.00 Educational Grants Ponce Event 360 Inc. $8,330.00 Corporate Sponsorship Excel Continuing Education $5,000.00 Educational Grants Excellence in Gastro $100,000.00 Corporate Sponsorship Education LLC Excellence in Rheumlgy $100,000.00 Corporate Sponsorship Education LLC Family Med Ctr Bolingbrook $13,000.00 Corporate Sponsorship Family Med Ctr Bolingbrook $5,500.00 Corporate Sponsorship Fdtn for Biomedical $25,000.00 Charitable Donations Research Federation of American $1,500.00 Educational Grants Socty Federation of American $1,500.00 Educational Grants Socty Federation of American $1,500.00 Educational Grants Socty Federation of American $1,500.00 Educational Grants Socty Federation of American $1,500.00 Educational Grants Socty Federation of American $1,500.00 Educational Grants Socty Federation of Clinical $20,000.00 Educational Grants Immunology Socty Federation of Clinical $25,000.00 Educational Grants Immunology Socty Federation of Clinical $12,500.00 Educational Grants Immunology Socty Florida Hlth Care Coalition $5,000.00 Corporate Sponsorship Florida Socty of $20,000.00 Corporate Sponsorship Dermatology Phys Assistants Inc. Florida Socty of Rheumlgy $25,000.00 Corporate Sponsorship Focus Med Communications $100,000.00 Corporate Sponsorship Force--Facing Our Risk of $10,000.00 Corporate Sponsorship Cancer Emp Force--Facing Our Risk of $10,000.00 Charitable Donations Cancer Emp Foster Ocular Immunology $40,000.00 Corporate Sponsorship Socty Foundation for Veterans $20,000.00 Corporate Sponsorship Health Care Foundation of Consortium of $12,280.00 Fellowships and Multiple Sclerosis Centers Scholarships CMSC Foundation of Consortium of $25,000.00 Educational Grants Multiple Sclerosis Centers CMSC Foundation of Consortium of $10,000.00 Charitable Donations Multiple Sclerosis Centers CMSC Friends of Cancer Research $50,000.00 Corporate Sponsorship Friends of Parkinsons $1,000.00 Corporate Sponsorship Friends of The St Louis $50,000.00 Corporate Sponsorship Univ Liver Ctr Fund for Public Hlth In New $200,000.00 Educational Grants York Fundacion Alfredo Ruiz $5,000.00 Corporate Sponsorship Fundacion Daledale Inc. $3,000.00 Corporate Sponsorship Fundacion De Esclerosis $3,000.00 Corporate Sponsorship Multiple De Puerto Rico Fundacion Puertorriquena De $5,000.00 Corporate Sponsorship Enfermedades Reumaticas Galien Foundation $22,500.00 Corporate Sponsorship Galien Foundation $30,000.00 Corporate Sponsorship Gastro--Intestinal Research $25,000.00 Corporate Sponsorship Fdtn Gastro--Intestinal Research $50,000.00 Corporate Sponsorship Fdtn Gastrointestinal And Liver $75,000.00 Educational Grants Association of The Americas Inc. Gateway for Cancer Research $10,000.00 Charitable Donations Georgetown Univ Hosp Phmcy $50,000.00 Fellowships and Scholarships Georgia Dermatology Phys $20,000.00 Corporate Sponsorship Assistants Georgia Doty Hiv & $10,000.00 Educational Grants Hepatitis Commty Outreach Inc. Georgia Prostate Cancer $2,500.00 Educational Grants Coalition The Georgia Society of Clinical $25,000.00 Corporate Sponsorship Oncology Georgia Socty of $8,000.00 Corporate Sponsorship Rhematology Global Academy for Medical $18,000.00 Corporate Sponsorship Education Global Academy for Medical $76,500.00 Corporate Sponsorship Education Global Academy for Medical $36,000.00 Corporate Sponsorship Education Global Academy for Medical $54,000.00 Corporate Sponsorship Education Global Academy for Medical $90,000.00 Corporate Sponsorship Education Global Alliance for Medical $10,000.00 Educational Grants Education Global Alliance for Patient $30,000.00 Corporate Sponsorship Access Global Biological Standards $2,000.00 Educational Grants Inst Globalization of $10,000.00 Corporate Sponsorship Pharmaceutics Education Ntwrk Good Grief $500.00 Corporate Sponsorship Gordon Research Conferences $1,500.00 Educational Grants Gordon Research Conferences $1,500.00 Educational Grants Gordon Research Conferences $10,000.00 Corporate Sponsorship Gordon Research Conferences $1,500.00 Educational Grants Gordon Research Conferences $1,500.00 Educational Grants Gordon Research Conferences $1,500.00 Educational Grants Gordon Research Conferences $1,500.00 Educational Grants Gordon Research Conferences $1,500.00 Educational Grants Gordon Research Conferences $1,500.00 Educational Grants Gordon Research Conferences $1,500.00 Educational Grants Gordon Research Conferences $1,500.00 Educational Grants Gordon Research Conferences $1,500.00 Educational Grants Gordon Research Conferences $1,500.00 Educational Grants Gordon Research Conferences $1,500.00 Educational Grants Gordon Research Conferences $1,500.00 Educational Grants Gordon Research Conferences $2,000.00 Educational Grants Gordon Research Conferences $1,500.00 Educational Grants Gordon Research Conferences $2,000.00 Educational Grants Gordon Research Conferences $2,000.00 Educational Grants Gordon Research Conferences $2,000.00 Educational Grants Gordon Research Conferences $2,000.00 Educational Grants Great Lakes Chapter of The $1,000.00 Corporate Sponsorship American Society for Pharmacology And Experimental Therapeutics Gynecologic Oncology Grp $35,000.00 Educational Grants The Gynecologic Oncology Grp $40,000.00 Educational Grants The Gynecologic Oncology Grp $40,000.00 Educational Grants The Haymarket Med Education ($2,553.09) Educational Grants Head for The Cure Fdtn $7,500.00 Corporate Sponsorship Healthcare Business Women's $7,500.00 Corporate Sponsorship Association, Inc. Healthcare Business Women's $7,500.00 Corporate Sponsorship Association, Inc. Healthwell Fdtn $507,000.00 Charitable Donations Healthy Women $30,000.00 Corporate Sponsorship Heart to Heart $10,000.00 Charitable Donations International Inc. Heart to Heart $50,000.00 Charitable Donations International Inc. Heb Grocery Company LP $7,000.00 Corporate Sponsorship Henry ford Hlth System $2,000.00 Corporate Sponsorship Henry M Jackson Fdtn $5,559.67 Corporate Sponsorship Henry M Jackson Fdtn $5,559.67 Corporate Sponsorship Henry M Jackson Fdtn $5,559.66 Corporate Sponsorship Henry M Jackson Fdtn $10,000.00 Educational Grants Hep C Connection $5,000.00 Corporate Sponsorship Hep C Connection $25,000.00 Charitable Donations Hep C Connection $5,000.00 Corporate Sponsorship Hepatitis C Asoc $25,000.00 Educational Grants Hepatitis Education Project $75,000.00 Charitable Donations Hepatitis Education Project $24,000.00 Corporate Sponsorship Hepatitis Education Project $25,000.00 Corporate Sponsorship Hepatitis Foundation $250,000.00 Corporate Sponsorship International Hepatitis Foundation $5,000.00 Corporate Sponsorship International Herbert Kosten Pancreatic $2,000.00 Corporate Sponsorship Cancer Charitable Fund Hidradenitis Suppurativa $13,550.00 Charitable Donations Fdtn Hitchcock Fdtn $8,000.00 Educational Grants Hitchcock Fdtn $20,000.00 Educational Grants HIV Treaters Med Asoc of $10,000.00 Educational Grants Puerto Rico Hlthcr Financial Mgmt Hfma $50,000.00 Corporate Sponsorship Hmp Communications $31,000.00 Corporate Sponsorship Hmp Communications $50,000.00 Corporate Sponsorship Hope Fdtn The $25,000.00 Educational Grants Hope Healthcare Services $600.00 Corporate Sponsorship Houston Area Parkinson $1,000.00 Corporate Sponsorship Society Houston Business Coalition $6,000.00 Corporate Sponsorship On Health Howard Hanna Children's $10,000.00 Charitable Donations Free Care Fund Hubbard Street Dance $10,000.00 Educational Grants Chicago Human Growth Fdtn $5,000.00 Corporate Sponsorship Human Growth Fdtn $10,000.00 Charitable Donations Human Growth Fdtn $4,000.00 Corporate Sponsorship Humboldt--Del Norte County $1,100.00 Educational Grants Med Socty Humboldt--Del Norte County $4,000.00 Educational Grants Med Socty Ibd Remedy Inc. $10,000.00 Charitable Donations Illinois African American $15,000.00 Corporate Sponsorship Coalition Illinois Socty of $25,000.00 Corporate Sponsorship Dermatology Phys Assistants Illinois Socty of $15,000.00 Corporate Sponsorship Dermatology Phys Assistants Imedex LLC $50,000.00 Educational Grants Imedex LLC $75,000.00 Educational Grants Imedex LLC $75,000.00 Educational Grants Imedex LLC $9,000.00 Educational Grants Imedex LLC $25,000.00 Educational Grants Imedex LLC $50,000.00 Educational Grants Imedex LLC ($838.00) Educational Grants Imedex LLC $50,000.00 Educational Grants Imedex LLC $75,000.00 Educational Grants Improve Care Now Inc. $15,000.00 Corporate Sponsorship Indian Medical Association $500.00 Corporate Sponsorship of New England Indiana Parkinson Fdtn $1,000.00 Corporate Sponsorship Indiana Univ ($619.24) Fellowships and Scholarships Indiana Univ Fdtn $50,000.00 Charitable Donations Inflammatory Bowel Disease $75,000.00 Educational Grants Support Fdtn Inflammatory Bowel Disease $200,000.00 Educational Grants Support Fdtn Inflammatory Bowel Disease $75,000.00 Educational Grants Support Fdtn Innovation Development Inst $250,000.00 Corporate Sponsorship Inc. Integrated Benefits Inst $25,000.00 Corporate Sponsorship Inc. Integrated Med Fdtn $15,000.00 Charitable Donations Interfaith House $2,000.00 Charitable Donations Intermountain Dermatology $15,000.00 Educational Grants Socty International Aids Socty-- $75,000.00 Educational Grants USA International Aids Socty-- $75,000.00 Educational Grants USA International Biometric $4,925.00 Corporate Sponsorship Socty Eastern North American Region International Chinese $3,000.00 Corporate Sponsorship Statistical Asoc International Dermatology $250,000.00 Educational Grants Outcome Measures International League of $20,000.00 Charitable Donations Asoc for Rheumlgy International Medical Corps $50,000.00 Charitable Donations International Organization $145,000.00 Educational Grants of Multiple Sclerosis Nurses International Organization $60,000.00 Educational Grants of Multiple Sclerosis Nurses International Parkinson And $300,000.00 Corporate Sponsorship Movemen International Socty for $5,000.00 Educational Grants Antiviral Research International Socty for The $3,000.00 Educational Grants Study of Xenobiotics International Socty for The $2,500.00 Educational Grants Study of Xenobiotics International Socty of $40,000.00 Corporate Sponsorship Nphro International Socty of $1,500.00 Educational Grants Psychiatric Genetics Iraq and Afghanistan $15,000.00 Corporate Sponsorship Veterans ISMPP--International Socty $10,000.00 Corporate Sponsorship for Med ISMPP--International Socty $10,000.00 Corporate Sponsorship for Med Jefferson Med Colg At $3,000.00 Corporate Sponsorship Thomas Jefferson Univ Jefferson Med Colg At $3,000.00 Corporate Sponsorship Thomas Jefferson Univ Jefferson Med Colg At $7,500.00 Educational Grants Thomas Jefferson Univ John P Mcgovern Museum of $10,000.00 Corporate Sponsorship Health And Medical Science Johns Hopkins Univ School $50,000.00 Educational Grants of Medicine Johns Hopkins Univ School $20,000.00 Educational Grants of Medicine Johns Hopkins Univ School $1,500.00 Corporate Sponsorship of Medicine Johns Hopkins Univ School $40,000.00 Fellowships and of Medicine Scholarships Johns Hopkins Univ School $99,750.00 Educational Grants of Medicine Johns Hopkins Univ School $35,000.00 Educational Grants of Medicine Johns Hopkins Univ School $7,000.00 Fellowships and of Medicine Scholarships Johns Hopkins Univ School $90,000.00 Educational Grants of Medicine Johns Hopkins Univ School $50,000.00 Educational Grants of Medicine JWC Covenant Inc. $25,000.00 Educational Grants Kansas Univ Neuro Fdtn $65,000.00 Educational Grants Kelsey Research Fdtn $35,000.00 Fellowships and Scholarships Kentuckiana Health $2,500.00 Corporate Sponsorship Collaborative Kentucky Life Sciences $5,000.00 Corporate Sponsorship Foundation Keystone Symposia $25,000.00 Corporate Sponsorship Laboratorio Clinico Toledo $2,955.00 Patient Support Laboratorio Clinico Toledo $810.00 Patient Support Laboratorio Clinico Toledo $720.00 Patient Support Laboratorio Clinico Toledo $675.00 Patient Support Laboratorio Clinico Toledo $675.00 Patient Support Laboratorio Clinico Toledo $630.00 Patient Support Laboratorio Clinico Toledo $1,440.00 Patient Support Laboratorio Clinico Toledo $1,485.00 Patient Support Laboratorio Clinico Toledo $5,250.00 Patient Support Laboratorio Clinico Toledo $735.00 Patient Support Laboratorio Clinico Toledo $810.00 Patient Support Laboratorio Clinico Toledo $660.00 Patient Support Laboratorio Clinico Toledo $1,875.00 Patient Support Laboratorio Clinico Toledo $825.00 Patient Support Laboratorio Clinico Toledo $765.00 Patient Support Laboratorio Clinico Toledo $750.00 Patient Support Laboratorio Clinico Toledo $1,500.00 Patient Support Laboratorio Clinico Toledo $885.00 Patient Support Laboratorio Clinico Toledo $1,740.00 Patient Support Laboratorio Clinico Toledo $1,500.00 Patient Support Laboratorio Clinico Toledo $810.00 Patient Support Laboratorio Clinico Toledo $1,500.00 Patient Support Laboratorio Clinico Toledo $1,500.00 Patient Support Laboratorio Clinico Toledo $372.00 Patient Support Laboratorio Clinico Toledo $2,550.00 Patient Support Laboratorio Clinico Toledo $1,470.00 Patient Support Laboratorio Clinico Toledo $1,350.00 Patient Support Laboratorio Clinico Toledo $1,215.00 Patient Support Laboratorio Clinico Toledo $1,080.00 Patient Support Laboratorio Clinico Toledo $705.00 Patient Support Laboratorio Clinico Toledo $645.00 Patient Support Laboratorio Clinico Toledo $204.00 Patient Support Laboratorio Clinico Toledo $1,500.00 Patient Support Laboratorio Clinico Toledo $765.00 Patient Support Laboratorio Clinico Toledo $1,905.00 Patient Support Laboratorio Clinico Toledo $1,500.00 Patient Support Laboratorio Clinico Toledo $675.00 Patient Support Laboratorio Clinico Toledo $585.00 Patient Support Laboratorio Clinico Toledo $885.00 Patient Support Laboratorio Clinico Toledo $870.00 Patient Support Laboratorio Clinico Toledo $1,500.00 Patient Support Laboratorio Clinico Toledo $1,500.00 Patient Support Laboratorio Clinico Toledo $975.00 Patient Support Laboratorio Clinico Toledo $1,080.00 Patient Support Laboratorio Clinico Toledo $1,035.00 Patient Support Laboratorio Clinico Toledo $300.00 Patient Support Laboratorio Clinico Toledo $870.00 Patient Support Laboratorio Clinico Toledo $1,500.00 Patient Support Laboratorio Clinico Toledo $1,305.00 Patient Support Laboratorio Clinico Toledo $1,200.00 Patient Support Laboratorio Clinico Toledo $645.00 Patient Support Laboratorio Clinico Toledo $1,500.00 Patient Support Laboratorio Clinico Toledo $1,500.00 Patient Support Laboratorio Clinico Toledo $1,290.00 Patient Support Laboratorio Clinico Toledo $1,005.00 Patient Support Laboratorio Clinico Toledo $204.00 Patient Support Laboratorio Clinico Toledo $1,500.00 Patient Support Laboratorio Clinico Toledo $1,140.00 Patient Support Laboratorio Clinico Toledo $1,125.00 Patient Support Laboratorio Clinico Toledo $810.00 Patient Support Laboratorio Clinico Toledo $240.00 Patient Support Laboratorio Clinico Toledo $1,395.00 Patient Support Laboratorio Clinico Toledo $1,275.00 Patient Support Laboratorio Clinico Toledo $705.00 Patient Support Laboratorio Clinico Toledo $1,425.00 Patient Support Laboratorio Clinico Toledo $1,200.00 Patient Support Laboratorio Clinico Toledo $675.00 Patient Support Laboratorio Clinico Toledo $405.00 Patient Support Laboratorio Clinico Toledo $1,095.00 Patient Support Laboratorio Clinico Toledo $720.00 Patient Support Laboratorio Clinico Toledo $660.00 Patient Support Laboratorio Clinico Toledo $495.00 Patient Support Laboratorio Clinico Toledo $2,355.00 Patient Support Laboratorio Clinico Toledo $1,200.00 Patient Support Laboratorio Clinico Toledo $2,295.00 Patient Support Laboratorio Clinico Toledo $915.00 Patient Support Lake County Haven $10,000.00 Charitable Donations Large Uro Grp Prct Asoc $20,000.00 Corporate Sponsorship Large Uro Grp Prct Asoc $25,000.00 Corporate Sponsorship Large Uro Grp Prct Asoc $25,000.00 Corporate Sponsorship Large Uro Grp Prct Asoc $25,000.00 Corporate Sponsorship Large Uro Grp Prct Asoc $66,400.00 Corporate Sponsorship Large Uro Grp Prct Asoc $25,000.00 Corporate Sponsorship Lenox Hill Hosp $10,000.00 Educational Grants Leukemia and Lymphoma $10,000.00 Educational Grants Society Leukemia and Lymphoma $10,000.00 Corporate Sponsorship Society Leukemia and Lymphoma $15,000.00 Corporate Sponsorship Society Leukemia and Lymphoma $4,000.00 Corporate Sponsorship Society Leukemia and Lymphoma $100,000.00 Corporate Sponsorship Society Leukemia and Lymphoma $2,500.00 Corporate Sponsorship Society Leukemia and Lymphoma $100,000.00 Charitable Donations Society Leukemia Research $5,000.00 Educational Grants Foundation Inc. Leukemia Research $5,000.00 Corporate Sponsorship Foundation Inc. Leukemia Research $5,000.00 Corporate Sponsorship Foundation Inc. Leukemia Research $50,000.00 Fellowships and Foundation Inc. Scholarships Leukemia Research $5,000.00 Charitable Donations Foundation Inc. Leukemia Research $5,000.00 Educational Grants Foundation Inc. Leukemia Research $10,000.00 Corporate Sponsorship Foundation Inc. Living Beyond Breast Cancer $10,000.00 Corporate Sponsorship Living Beyond Breast Cancer $10,000.00 Corporate Sponsorship Loyola Stritch School of $2,000.00 Educational Grants Medicine Div of Dermatology Lung Cancer Alliance $25,000.00 Corporate Sponsorship Lungevity Foundation $25,000.00 Corporate Sponsorship Lungevity Foundation $25,000.00 Corporate Sponsorship Lupus and Allied Diseases $6,000.00 Corporate Sponsorship Association Lymphoma Research $2,500.00 Corporate Sponsorship Foundation Lymphoma Research $10,000.00 Corporate Sponsorship Foundation Lymphoma Research $10,000.00 Corporate Sponsorship Foundation Lymphoma Research $2,000.00 Corporate Sponsorship Foundation Lymphoma Research $37,500.00 Corporate Sponsorship Foundation Magee--Womens Research Inst $10,000.00 Corporate Sponsorship And Fdtn Magellan Rx Mgmt Inc. $20,000.00 Corporate Sponsorship Magic Fdtn $15,000.00 Educational Grants Magic Fdtn $10,000.00 Charitable Donations Massachusetts Association $5,000.00 Corporate Sponsorship for Mental Health Massachusetts Inst of Tech $1,000.00 Charitable Donations Massachusetts Prostate $2,500.00 Educational Grants Cancer Coalition Inc. Massachusetts Socty for Med $5,000.00 Educational Grants Research Massachusetts Socty for Med $5,000.00 Educational Grants Research Massachusetts Socty of $5,000.00 Corporate Sponsorship Clinical Oncologists Max Foundation $45,000.00 Corporate Sponsorship Mayo Clnc $10,000.00 Educational Grants Mayo Clnc $2,500.00 Educational Grants Mccourt Fdtn Inc. $5,000.00 Educational Grants Me Strong Inc. $2,500.00 Corporate Sponsorship Med--LQ LLC $125,000.00 Educational Grants Med--LQ LLC $185,000.00 Educational Grants Med--LQ LLC $150,000.00 Educational Grants Med--LQ LLC $167,933.00 Educational Grants Med Colg of Wisconsin $7,500.00 Educational Grants Med Colg of Wisconsin $85,000.00 Educational Grants Med Colg of Wisconsin $2,000.00 Corporate Sponsorship Med Colg of Wisconsin $10,000.00 Educational Grants Med Conference Planners $10,000.00 Corporate Sponsorship Med Learning Inst $180,000.00 Educational Grants Med Learning Inst $72,015.00 Educational Grants Med Learning Inst $100,000.00 Educational Grants Med Learning Inst $65,000.00 Educational Grants Med Learning Inst $70,000.00 Educational Grants Med Learning Inst $40,000.00 Educational Grants Med Learning Inst $150,000.00 Educational Grants Med Learning Inst $65,380.00 Educational Grants Med Learning Inst $125,000.00 Educational Grants Medicinal And Bioorganic $5,000.00 Educational Grants Chemistry Fdtn The Medscape LLC $450,000.00 Educational Grants Medscape LLC $200,000.00 Educational Grants Medscape LLC $189,500.00 Educational Grants Medscape LLC $250,000.00 Educational Grants Medscape LLC $252,350.00 Educational Grants Medscape LLC $175,000.00 Educational Grants Medscape LLC $135,000.00 Educational Grants Medscape LLC $100,000.00 Educational Grants Medscape LLC $385,000.00 Educational Grants Medscape LLC $350,000.00 Educational Grants Medscape LLC $150,000.00 Educational Grants Medscape LLC $100,000.00 Educational Grants Medscape LLC $165,000.00 Educational Grants Medscape LLC $195,000.00 Educational Grants Medscape LLC $65,000.00 Educational Grants Medscape LLC $41,000.00 Educational Grants Medscape LLC $250,000.00 Educational Grants Medscape LLC ($2,000.00) Educational Grants Medscape LLC $300,000.00 Educational Grants Medscape LLC $112,500.00 Educational Grants Medstar Washington Hosp Ctr $10,000.00 Educational Grants Meeting Designs LLC $25,000.00 Corporate Sponsorship Memorial Sloan Kettering $10,000.00 Educational Grants Cancer Ctr Memphis Business Grp On $5,120.00 Corporate Sponsorship Hlth Memphis Business Grp On $5,120.00 Corporate Sponsorship Hlth Meridian Hospitals $400.00 Corporate Sponsorship Corporation Methodist Hosp The $25,000.00 Corporate Sponsorship Metropolitan Chicago Breast $10,000.00 Charitable Donations Cancer Michael J Fox Fdtn $1,000.00 Corporate Sponsorship Michael J Fox Fdtn $25,000.00 Corporate Sponsorship Michael J Fox Fdtn $50,000.00 Corporate Sponsorship Michael J Fox Fdtn $15,000.00 Educational Grants Michigan Parkinson $2,000.00 Corporate Sponsorship Foundation Michigan Parkinson $4,000.00 Corporate Sponsorship Foundation Michigan Parkinson $2,500.00 Corporate Sponsorship Foundation Michigan Rheumatism Socty $5,000.00 Corporate Sponsorship Michigan Rheumatism Socty $5,000.00 Corporate Sponsorship Michigan Rheumatism Socty $5,000.00 Corporate Sponsorship Michigan State Univ $1,000.00 Charitable Donations Michigan State Univ $1,000.00 Charitable Donations Midwest Business Grp On $5,000.00 Corporate Sponsorship Hlth Midwest Pediatric Endocrine $6,300.00 Corporate Sponsorship Socty Miles for Cystic Fibrosis $20,000.00 Charitable Donations Miles for Cystic Fibrosis $5,000.00 Corporate Sponsorship Missouri Hepatitis C $25,000.00 Charitable Donations Alliance Montana Asoc of Hlth Care $2,000.00 Corporate Sponsorship Purchaser Montefiore Med Ctr $75,000.00 Educational Grants Montefiore Med Ctr $50,000.00 Educational Grants Montefiore Med Ctr $50,000.00 Educational Grants Mount Sinai School of $95,000.00 Educational Grants Medicine Mount Sinai School of $40,000.00 Educational Grants Medicine Mount Sinai School of $15,000.00 Educational Grants Medicine Mount Sinai School of $100,000.00 Educational Grants Medicine Mount Sinai School of $2,500.00 Educational Grants Medicine Mount Sinai School of $5,000.00 Educational Grants Medicine Mount Sinai School of $40,000.00 Educational Grants Medicine Mount Sinai School of $1,500.00 Educational Grants Medicine Mount Sinai School of $30,000.00 Corporate Sponsorship Medicine Mount Sinai School of $15,000.00 Educational Grants Medicine Mount Sinai School of $1,500.00 Educational Grants Medicine Movement Disorder Socty The $20,000.00 Corporate Sponsorship Movement Disorder Socty The $25,000.00 Corporate Sponsorship Movement Disorder Socty The $9,900.00 Corporate Sponsorship Ms Cure Fund, Inc. $10,000.00 Educational Grants Ms Cure Fund, Inc. $50,000.00 Educational Grants Ms Cure Fund, Inc. $15,000.00 Educational Grants Ms Views And News Inc. $9,000.00 Educational Grants Multiple Myeloma Research $20,000.00 Educational Grants Fdtn Inc. The Multiple Myeloma Research $50,000.00 Educational Grants Fdtn Inc. The Multiple Myeloma Research $40,000.00 Corporate Sponsorship Fdtn Inc. The Nashville Cares Inc. $8,000.00 Corporate Sponsorship National Alliance of Mental $5,000.00 Corporate Sponsorship Illness Flordia National Alliance of Mental $15,000.00 Corporate Sponsorship Illness Michigan National Alliance of Mental $5,000.00 Corporate Sponsorship Illness Tennessee National Alliance of Mental $5,000.00 Corporate Sponsorship Illness Washington National Alliance of State $30,000.00 Corporate Sponsorship and Territorial AIDS Directors National Association of $6,750.00 Corporate Sponsorship Hispanic Nurses National Association of $6,750.00 Corporate Sponsorship Hispanic Nurses National Association of $25,000.00 Corporate Sponsorship Latino Elected & Appointed officials Educational Fund National Brain Tumor $15,000.00 Corporate Sponsorship Society (Nbts) National Brain Tumor $50,000.00 Charitable Donations Society (Nbts) National Brain Tumor $25,000.00 Corporate Sponsorship Society, Inc National Coalition for $40,000.00 Corporate Sponsorship Cancer National Comprehensive $15,000.00 Corporate Sponsorship Cancer Network National Comprehensive $10,000.00 Corporate Sponsorship Cancer Network National Comprehensive $15,000.00 Corporate Sponsorship Cancer Network National Comprehensive $10,000.00 Corporate Sponsorship Cancer Network National Comprehensive $15,000.00 Corporate Sponsorship Cancer Network National Hemophlia $5,000.00 Corporate Sponsorship Foundation National Minority Quality $10,000.00 Corporate Sponsorship forum Inc. National Ms Society Upper $2,500.00 Corporate Sponsorship Midwest Chapter National Multiple Sclerosis $250,000.00 Corporate Sponsorship Society National Parkinson $2,500.00 Corporate Sponsorship Foundation Minnesota National Parkinson $2,500.00 Corporate Sponsorship Foundation Minnesota National Parkinson $1,000.00 Corporate Sponsorship Foundation Minnesota National Parkinson $2,500.00 Corporate Sponsorship Foundation Minnesota Nationwide Childrens Hosp $5,000.00 Corporate Sponsorship Fdtn Natl Academy of Dermatology $30,000.00 Corporate Sponsorship Nurse Practitioners Natl Aids Treatment $300,000.00 Charitable Donations Advocacy Project Natl Alliance of State And $100,000.00 Charitable Donations Territorial Aids Directors Natl Asoc of Managed Care $30,000.00 Educational Grants Phys Natl Asoc of Managed Care $45,000.00 Educational Grants Phys Natl Asoc of Managed Care $40,000.00 Educational Grants Phys Natl Asoc of Managed Care $25,000.00 Corporate Sponsorship Phys Natl Asoc of Managed Care $35,000.00 Educational Grants Phys Natl Breast Cancer $5,000.00 Charitable Donations Coalition Fund Natl Business Coalition On $50,000.00 Corporate Sponsorship Hlth Natl Commission On $10,000.00 Educational Grants Correctional Hlth Care Natl Commission On $7,500.00 Corporate Sponsorship Correctional Hlth Care Natl Commission On $7,500.00 Corporate Sponsorship Correctional Hlth Care Natl Committee for Quality $100,000.00 Corporate Sponsorship Assurance Natl Committee for Quality $95,000.00 Educational Grants Assurance Natl Comprehensive Cancer $50,000.00 Charitable Donations Ntwrk Natl Comprehensive Cancer $40,000.00 Corporate Sponsorship Ntwrk Natl Comprehensive Cancer $50,000.00 Educational Grants Ntwrk Natl Comprehensive Cancer $5,000.00 Educational Grants Ntwrk Natl Comprehensive Cancer $25,000.00 Educational Grants Ntwrk Natl Comprehensive Cancer $25,000.00 Charitable Donations Ntwrk Natl Comprehensive Cancer $50,000.00 Educational Grants Ntwrk Natl Comprehensive Cancer $50,000.00 Corporate Sponsorship Ntwrk Natl Comprehensive Cancer $50,000.00 Educational Grants Ntwrk Natl Comprehensive Cancer $40,000.00 Educational Grants Ntwrk Natl Comprehensive Cancer $240,000.00 Corporate Sponsorship Ntwrk Natl Comprehensive Cancer $75,000.00 Educational Grants Ntwrk Natl Multiple Sclerosis $10,000.00 Corporate Sponsorship Socty Natl Organization of $5,000.00 Corporate Sponsorship Rheumlgy Managers Natl Pancreas Fdtn $200,000.00 Educational Grants Natl Pancreas Fdtn $85,000.00 Educational Grants Natl Pancreas Fdtn $85,000.00 Charitable Donations Natl Pancreas Fdtn $75,000.00 Charitable Donations Natl Pancreas Fdtn $70,000.00 Educational Grants Natl Pancreas Fdtn $1,000.00 Corporate Sponsorship Natl Pancreas Fdtn $75,000.00 Corporate Sponsorship Natl Pancreas Fdtn $7,500.00 Corporate Sponsorship Natl Pancreas Fdtn $2,500.00 Corporate Sponsorship Natl Pancreas Fdtn $200,000.00 Educational Grants Natl Pancreas Fdtn $25,000.00 Corporate Sponsorship Natl Pancreas Fdtn $75,000.00 Corporate Sponsorship Natl Parkinson Fdtn Inc. $75,000.00 Corporate Sponsorship Natl Parkinson Fdtn Inc. $2,500.00 Corporate Sponsorship Natl Parkinson Fdtn Inc. $5,000.00 Corporate Sponsorship Natl Parkinson Fdtn Inc. $2,500.00 Corporate Sponsorship Natl Parkinson Fdtn Inc. $1,000.00 Corporate Sponsorship Natl Parkinson Fdtn Inc. $1,500.00 Corporate Sponsorship Natl Parkinson Fdtn Inc. $10,000.00 Corporate Sponsorship Natl Parkinson Fdtn Inc. $50,000.00 Educational Grants Natl Parkinson Fdtn Inc. $10,000.00 Corporate Sponsorship Natl Parkinson Fdtn Inc. $85,000.00 Corporate Sponsorship Natl Psoriasis Fdtn $25,000.00 Corporate Sponsorship Natl Psoriasis Fdtn $75,000.00 Educational Grants Natl Psoriasis Fdtn $50,000.00 Educational Grants Natl Psoriasis Fdtn $30,000.00 Educational Grants Natl Psoriasis Fdtn $26,000.00 Corporate Sponsorship Natl Psoriasis Fdtn $26,000.00 Corporate Sponsorship Natl Psoriasis Fdtn $26,000.00 Corporate Sponsorship Natl Psoriasis Fdtn $26,000.00 Corporate Sponsorship Natl Psoriasis Fdtn $20,000.00 Corporate Sponsorship Natl Psoriasis Fdtn $10,000.00 Corporate Sponsorship Natl Psoriasis Fdtn $13,550.00 Charitable Donations Natl Psoriasis Fdtn $50,000.00 Educational Grants Natl Psoriasis Fdtn $20,000.00 Corporate Sponsorship Natl Psoriasis Fdtn $50,000.00 Corporate Sponsorship Natl Psoriasis Fdtn $50,000.00 Corporate Sponsorship Natl Psoriasis Fdtn $40,000.00 Corporate Sponsorship Natl Psoriasis Fdtn $2,500.00 Corporate Sponsorship Natl Psoriasis Fdtn $150,000.00 Corporate Sponsorship Natl Psoriasis Fdtn $20,000.00 Corporate Sponsorship Natl Psoriasis Fdtn $100,000.00 Corporate Sponsorship Natl Psoriasis Fdtn $40,000.00 Corporate Sponsorship Natl Psoriasis Fdtn $30,000.00 Corporate Sponsorship Natl Psoriasis Fdtn $20,000.00 Corporate Sponsorship Natl Socty for Cutaneous $50,000.00 Corporate Sponsorship Medicine Natl Socty for Cutaneous $75,000.00 Corporate Sponsorship Medicine Natl Socty for Cutaneous $135,000.00 Corporate Sponsorship Medicine Natl Socty for Cutaneous $135,000.00 Corporate Sponsorship Medicine Neuro Challenge Foundation $7,500.00 Educational Grants Inc. Neurologic Disease $4,995.00 Educational Grants Foundation New Jersey Academy of $105,000.00 Educational Grants Family Phys New Mexico Parkinsons $3,500.00 Educational Grants Disease Coalition New York Academy of Scnc $1,500.00 Educational Grants New York Academy of Scnc $1,500.00 Educational Grants New York Socty for $2,000.00 Corporate Sponsorship Gastrointestinal Endoscopy New York State Council of $11,500.00 Corporate Sponsorship Hlth-System Pharmacists New York State Rheumlgy $18,000.00 Corporate Sponsorship Socty New York Univ School of $20,000.00 Educational Grants Medicine New York Univ School of $10,000.00 Educational Grants Medicine New York Univ School of $5,000.00 Educational Grants Medicine New York Univ School of $5,000.00 Educational Grants Medicine New York Univ School of $10,000.00 Educational Grants Medicine New York Univ School of $10,000.00 Educational Grants Medicine New York Univ School of $20,000.00 Educational Grants Medicine Nexus Global Grp Scnc $10,000.00 Corporate Sponsorship Nicole Jarvis Md Parkinsons $1,000.00 Corporate Sponsorship Research Fdtn NL Communications Inc. $50,000.00 Educational Grants NL Communications Inc. $35,000.00 Educational Grants NL Communications Inc. $40,000.00 Educational Grants NL Communications Inc. $50,000.00 Educational Grants NL Communications Inc. $15,000.00 Educational Grants NL Communications Inc. $50,000.00 Educational Grants NL Communications Inc. $50,000.00 Educational Grants NL Communications Inc. $100,000.00 Educational Grants NL Communications Inc. $50,000.00 Educational Grants NL Communications Inc. $10,000.00 Educational Grants NL Communications Inc. $25,000.00 Educational Grants NL Communications Inc. $25,000.00 Educational Grants NL Communications Inc. $40,000.00 Educational Grants NL Communications Inc. $25,000.00 Educational Grants NL Communications Inc. ($40,000.00) Educational Grants NL Communications Inc. $128,000.00 Educational Grants NL Communications Inc. $125,000.00 Educational Grants NL Communications Inc. $75,000.00 Educational Grants NL Communications Inc. $65,000.00 Educational Grants NL Communications Inc. $50,000.00 Educational Grants NL Communications Inc. $35,000.00 Educational Grants NL Communications Inc. $25,000.00 Educational Grants NL Communications Inc. $20,000.00 Educational Grants North American Ctr for $390,000.00 Educational Grants Continuing Med Education (NACCME, LLC) North American Ctr for $90,000.00 Educational Grants Continuing Med Education (NACCME, LLC) North American Ctr for $90,000.00 Educational Grants Continuing Med Education (NACCME, LLC) North American Ctr for $100,000.00 Educational Grants Continuing Med Education (NACCME, LLC) North American Socty for $31,000.00 Educational Grants Pediatric Gastro Hepatology And Nutrition North American Socty for $40,000.00 Fellowships and Pediatric Gastro Scholarships Hepatology And Nutrition North Dakota Pharmacists $2,500.00 Corporate Sponsorship Asoc North Dakota Society of $1,750.00 Corporate Sponsorship Health System Pharmacists North Eastern Section of $3,000.00 Corporate Sponsorship The American Chemical Society, Inc. North Memorial Commty Fdtn $2,500.00 Corporate Sponsorship Northeast Business Grp On $5,000.00 Corporate Sponsorship Hlth Northeast Business Grp On $5,000.00 Corporate Sponsorship Hlth Northwest Health Law $1,000.00 Corporate Sponsorship Advocates Northwest Kdny Centers $2,500.00 Corporate Sponsorship Northwest Parkinsons Fdtn $7,000.00 Educational Grants Northwest Parkinsons Fdtn $5,000.00 Corporate Sponsorship Northwest Parkinsons Fdtn $5,000.00 Educational Grants Northwestern Memorial Fdtn $8,000.00 Educational Grants Northwestern Univ $25,000.00 Corporate Sponsorship Northwestern Univ $50,000.00 Fellowships and Scholarships Northwestern Univ $5,000.00 Educational Grants Northwestern Univ $5,000.00 Educational Grants Northwestern Univ $2,000.00 Educational Grants Norton Hlthcr Inc. $3,000.00 Corporate Sponsorship Ocular Immunology And $2,500.00 Corporate Sponsorship Uveitis Fdtn Ohio Asoc of Rheumlgy $10,000.00 Corporate Sponsorship Ohio Gastro Socty $5,000.00 Corporate Sponsorship Omnia Education Inc. $95,000.00 Educational Grants Oncology Nursing Socty $15,000.00 Educational Grants Oncology Nursing Socty $38,500.00 Corporate Sponsorship Open Doors Commty School $2,000.00 Charitable Donations Oregon Hlth & Scnc Univ $10,000.00 Educational Grants Oregon Hlth & Scnc Univ $2,000.00 Educational Grants Oregon Hlth & Scnc Univ $5,000.00 Educational Grants Oregon Hlth & Scnc Univ $10,000.00 Educational Grants Oregon State University $7,500.00 Corporate Sponsorship Foundation Organic Reactions Catalysis $1,000.00 Educational Grants Socty Ostomy Asoc of Greater $1,000.00 Corporate Sponsorship Chicago Ounce of Prevention Fund $10,000.00 Charitable Donations Pacific Dermatologic Asoc $10,000.00 Corporate Sponsorship Pacific Dermatologic Asoc $20,000.00 Corporate Sponsorship Pack Hlth LLC $91,375.00 Educational Grants Pack Hlth LLC $175,000.00 Educational Grants Pack Hlth LLC $127,800.00 Educational Grants Pack Hlth LLC $108,875.00 Educational Grants Pancreas Club The $10,000.00 Educational Grants Pancreatic Cancer Action $1,250.00 Corporate Sponsorship Ntwrk Inc. Pancreatic Cancer Action $1,250.00 Corporate Sponsorship Ntwrk Inc. Pancreatic Cancer Action $25,000.00 Corporate Sponsorship Ntwrk Inc. Pancreatic Cancer Action $234,000.00 Corporate Sponsorship Ntwrk Inc. Park Nicollet $1,000.00 Corporate Sponsorship Parkinson Alliance Inc. $1,000.00 Corporate Sponsorship Parkinson And Movement $15,000.00 Educational Grants Disorder All Parkinson And Movement $1,250.00 Corporate Sponsorship Disorder All Parkinson And Movement $50,000.00 Educational Grants Disorder All Parkinson Asoc of The $8,000.00 Educational Grants Rockies Parkinson Asoc of The $6,000.00 Educational Grants Rockies Parkinson Association of $500.00 Corporate Sponsorship Alabama Parkinson Association of $500.00 Corporate Sponsorship Central Florida Inc. Parkinson Council $20,000.00 Corporate Sponsorship Parkinson Fdtn of The Natl $10,000.00 Educational Grants Capital Area Parkinson Foundation of $1,000.00 Corporate Sponsorship Oklahoma Parkinson Foundation of $1,500.00 Corporate Sponsorship Oklahoma Parkinson Institute $5,000.00 Corporate Sponsorship Parkinson Ntwrk of Arizona $2,500.00 Corporate Sponsorship Parkinson Society of $500.00 Corporate Sponsorship Greenville Area Parkinson Study Group $10,000.00 Educational Grants Parkinson Support Center of $2,500.00 Corporate Sponsorship Kentuciana Parkinson Support Center of $5,000.00 Corporate Sponsorship Kentuciana Parkinson Wellness Recovery $1,000.00 Corporate Sponsorship Parkinsons And Movement $2,500.00 Corporate Sponsorship Disorder Foundation Parkinsons Asoc of Western $1,500.00 Corporate Sponsorship Michigan Parkinsons Disease Fdtn $25,000.00 Educational Grants Parkinsons Disease Fdtn $50,000.00 Educational Grants Parkinsons Disease Fdtn $7,500.00 Corporate Sponsorship Parkinsons Outreach $1,000.00 Corporate Sponsorship Association Parkinsons Resources of $5,000.00 Corporate Sponsorship Oregon Parkinsons Resources of $5,000.00 Corporate Sponsorship Oregon Parkinsons Unity Walk $50,000.00 Corporate Sponsorship Parkinsons Unity Walk $64,000.00 Corporate Sponsorship Partners Hlthcr System ($10,000.00) Educational Grants Partnership for A Drug Free $50,000.00 Charitable Donations America Partnership for Quality Med $2,000.00 Charitable Donations Donations Pqmd Partnership for Quality Med $1,000.00 Charitable Donations Donations Pqmd Patient Access Ntwrk Fdtn $8,400,000.00 Charitable Donations Patient Access Ntwrk Fdtn $260,000.00 Charitable Donations Patient Access Ntwrk Fdtn $557,000.00 Charitable Donations Patient Empowerment Ntwrk $75,000.00 Educational Grants Patient Empowerment Ntwrk $40,000.00 Educational Grants Patient Empowerment Ntwrk $22,500.00 Educational Grants Patient Empowerment Ntwrk $20,000.00 Educational Grants Patient Empowerment Ntwrk $22,500.00 Educational Grants Patient Empowerment Ntwrk $35,000.00 Educational Grants Patient Empowerment Ntwrk $20,000.00 Educational Grants Patient Empowerment Ntwrk $35,000.00 Educational Grants Patient Empowerment Ntwrk $10,000.00 Educational Grants Patient Power LLC $90,000.00 Corporate Sponsorship Pediatric Endocrinology $6,000.00 Corporate Sponsorship Nursing Socty Pediatric Endocrinology $10,000.00 Charitable Donations Nursing Socty Pediatric Splts of Virginia $2,000.00 Corporate Sponsorship LLC Pennsylvania Academy of $13,550.00 Corporate Sponsorship Dermatology And Dermatologic Surgry Pennsylvania Socty of $10,000.00 Corporate Sponsorship Gastro Pennsylvania State Univ $15,000.00 Educational Grants Pennsylvania State Univ $15,000.00 Educational Grants Pennsylvania State Univ ($36,337.33) Educational Grants Pennsylvania State Univ $20,000.00 Educational Grants Phmcy Quality Alliance $12,500.00 Educational Grants Phoenix Childrens Hosp $1,000.00 Corporate Sponsorship Phys Education Resource $25,000.00 Educational Grants Phys Education Resource $75,000.00 Educational Grants Phys Education Resource $25,000.00 Educational Grants Phys Education Resource $25,000.00 Educational Grants Phys Education Resource $25,000.00 Educational Grants Phys Education Resource $50,000.00 Educational Grants Phys Education Resource $50,000.00 Educational Grants Phys Education Resource $50,000.00 Educational Grants Phys Education Resource $75,000.00 Educational Grants Phys Education Resource $50,000.00 Educational Grants Pins for Parkinsons $500.00 Corporate Sponsorship Pittsburgh Business Grp On $3,800.00 Corporate Sponsorship Hlth Pittsburgh Business Grp On $3,800.00 Corporate Sponsorship Hlth President And Fellows of $6,000.00 Educational Grants Harvard Colg Prevent Cancer Fdtn $25,000.00 Charitable Donations Prime Education Inc. $100,000.00 Educational Grants Prime Education Inc. $200,000.00 Educational Grants Prime Education Inc. $218,348.25 Educational Grants Prime Education Inc. $500,000.00 Educational Grants Prime Education Inc. $200,000.00 Educational Grants Prime Oncology Inc. $85,000.00 Educational Grants Prime Oncology Inc. $142,376.00 Educational Grants Prime Oncology Inc. $50,000.00 Educational Grants Prime Oncology Inc. $75,000.00 Educational Grants Prime Oncology Inc. $85,000.00 Educational Grants Princeton Univ Trustees $50,000.00 Fellowships and Scholarships Proce Inc. $15,000.00 Educational Grants Project Access Now $3,500.00 Corporate Sponsorship Project Inform Inc. $75,000.00 Charitable Donations Project Inform Inc. $30,000.00 Corporate Sponsorship Projects In Knowledge Inc. $100,000.00 Educational Grants Promedica International Cme $15,000.00 Educational Grants Promis Hlth Organization $5,000.00 Educational Grants Prostate Cancer Foundation $4,000.00 Corporate Sponsorship Chicago Prostate Cancer Research $10,000.00 Educational Grants Inst Prostate Cancer Research $15,000.00 Corporate Sponsorship Inst Prostate Hlth Education $15,000.00 Educational Grants Ntwrk Prostate Hlth Education $10,000.00 Educational Grants Ntwrk Prostate Net Inc. The $15,000.00 Educational Grants Prostaware $1,000.00 Corporate Sponsorship Puerto Rico Academy of $16,000.00 Corporate Sponsorship Family Phys Puerto Rico Asoc of Gastro $15,000.00 Educational Grants Puerto Rico Asoc of Gastro $30,000.00 Corporate Sponsorship Puerto Rico Asoc of Gastro $6,500.00 Educational Grants Purdue Univ $200,000.00 Educational Grants Purdue Univ $250,000.00 Educational Grants Purdue Univ ($60,000.00) Educational Grants Regents of The Univ of $10,000.00 Educational Grants California The Regents of The Univ of $5,000.00 Educational Grants California The Regents of The Univ of $40,000.00 Fellowships and California The Scholarships Regents of The Univ of $5,000.00 Educational Grants California The Regents of The Univ of $15,000.00 Educational Grants California The Regents of The Univ of $50,000.00 Fellowships and California The Scholarships Regents of The Univ of $2,500.00 Educational Grants California The Regents of The Univ of $10,000.00 Educational Grants California The Regents of The Univ of $5,000.00 Educational Grants Michigan Regents of The Univ of $10,000.00 Corporate Sponsorship Michigan Regents of The Univ of $1,000.00 Educational Grants Michigan Regional Osteopathic Med $165,000.00 Educational Grants Education Renal Phys Asoc $30,000.00 Corporate Sponsorship Respiratory Hlth Asoc of $4,050.00 Corporate Sponsorship Metro Chicago Rheumatism Socty of The $15,000.00 Corporate Sponsorship District of Columbia The Rheumatology Association of $5,000.00 Corporate Sponsorship Nevada Rheumlgy Alliance of $25,000.00 Corporate Sponsorship Louisiana Rheumlgy Nurses Socty $80,000.00 Educational Grants Rheumlgy Nurses Socty $31,875.00 Corporate Sponsorship Rheumlgy Nurses Socty $5,000.00 Corporate Sponsorship Rheumlgy Nurses Socty $25,000.00 Educational Grants Rheumlgy Nurses Socty $44,625.00 Corporate Sponsorship Riverside Medical Clinic $7,500.00 Educational Grants Charitable Foundation Robert Michael Educational $123,500.00 Educational Grants Inst LLC Robert Michael Educational $80,000.00 Educational Grants Inst LLC Rock Steady Boxing $500.00 Corporate Sponsorship Rocky Mountain Ms Center $5,000.00 Educational Grants Rush Univ Med Ctr $50,000.00 Educational Grants Rush Univ Med Ctr $75,000.00 Educational Grants Rush Univ Med Ctr $35,000.00 Educational Grants Rutgers The State Univ of $60,000.00 Educational Grants New Jersey Rutgers The State Univ of $25,000.00 Educational Grants New Jersey Rutgers The State Univ of $50,000.00 Educational Grants New Jersey Rutgers University $1,500.00 Educational Grants Foundation Safety Pharmacology Socty $2,000.00 Educational Grants Saint Anthony Hosp Fdtn $1,500.00 Educational Grants San Francisco Neuro Socty $1,500.00 Educational Grants San Francisco Retina $5,000.00 Educational Grants Foundation San Juan Bautista Med $40,000.00 Fellowships and Scholarships Scott And White Healthcare $1,000.00 Corporate Sponsorship Foundation Scripps Hlth $5,000.00 Educational Grants Scripps Hlth $50,000.00 Educational Grants Scripps Hlth $5,000.00 Educational Grants Scripps Hlth $5,000.00 Educational Grants Scripps Hlth $50,000.00 Educational Grants Scripps Hlth $25,000.00 Educational Grants Scripps Research Inst. $5,000.00 Fellowships and Scholarships Scripps Research Inst. $2,000.00 Educational Grants Seattle Science Foundation $7,500.00 Educational Grants Sexual Medicine Socty of ($25,000.00) Educational Grants North Am Sexual Medicine Socty of $225,000.00 Corporate Sponsorship North America Inc. Share $10,000.00 Patient Support Sheknows LLC $43,000.00 Corporate Sponsorship Smith Wholesale Drug $9,000.00 Corporate Sponsorship Company Sociedad Dermatologica De $15,000.00 Corporate Sponsorship Puerto Rico Sociedad Dermatologica De $35,000.00 Corporate Sponsorship Puerto Rico Sociedad Pr Endocrinologia $15,000.00 Corporate Sponsorship Y Diabetologia Sociedad Puertorriquena $8,000.00 Corporate Sponsorship Pediatria Society for Mucosal $1,500.00 Educational Grants Immunology Society for Neuro-Oncology $10,000.00 Educational Grants Society for Neuro-Oncology $107,400.00 Corporate Sponsorship Society for Neuro-Oncology $25,000.00 Corporate Sponsorship Society of Nuclear Medicine $5,000.00 Corporate Sponsorship and Molecular Imaging Socty for Immunotherapy of $5,000.00 Educational Grants Cancer Socty for Leukocyte Biology $1,500.00 Educational Grants Socty for Neuroscience $2,500.00 Educational Grants Socty for Translational $10,000.00 Educational Grants Oncology Socty of Dermatology Phys $45,000.00 Corporate Sponsorship Assistants Socty of Dermatology Phys $20,000.00 Corporate Sponsorship Assistants Socty of Dermatology Phys $40,000.00 Corporate Sponsorship Assistants Socty of Investigative $30,000.00 Educational Grants Dermatology Socty of Toxicologic $1,000.00 Corporate Sponsorship Pathology Socty of Toxicologic $15,000.00 Corporate Sponsorship Pathology Socty of Toxicology $450.00 Corporate Sponsorship Socty of Toxicology $2,500.00 Corporate Sponsorship South Carolina Alliance of $5,000.00 Corporate Sponsorship Hlth Plans South Carolina $5,000.00 Corporate Sponsorship Dermatological Asoc South Dakota Parkinson $500.00 Corporate Sponsorship Foundation South Texas Asoc of $40,000.00 Corporate Sponsorship Rheumatologists Southeastern Consortium for $10,000.00 Corporate Sponsorship Dermatology Splty Pharma Education Ctr $49,750.00 Educational Grants St Louise Regional Hosp ($2,000.00) Educational Grants State of Maryland $40,000.00 Fellowships and Scholarships State of Maryland $5,500.00 Educational Grants State of Maryland $23,000.00 Educational Grants Super Jake Fdtn The $25,000.00 Charitable Donations Susan G Komen Philadelphia $3,500.00 Educational Grants Take A Breather Foundation $10,000.00 Corporate Sponsorship Take A Breather Foundation $2,500.00 Corporate Sponsorship Take A Breather Foundation $15,000.00 Corporate Sponsorship Tarsus Cardio Inc. Dba $35,000.00 Corporate Sponsorship South Beach Symposium Team Fox North Texas $1,000.00 Corporate Sponsorship Tennessee Dermatology Socty $4,000.00 Corporate Sponsorship Tennessee Disability $5,000.00 Corporate Sponsorship Coalition Tennessee Disability $2,500.00 Corporate Sponsorship Coalition Tennessee Nurses $6,000.00 Corporate Sponsorship Association Teratology Socty $2,000.00 Corporate Sponsorship Texas Academy of Family $2,500.00 Corporate Sponsorship Physicians Texas Medical Association $3,000.00 Corporate Sponsorship Texas Medical Association $10,000.00 Corporate Sponsorship Texas Neuro Socty $5,000.00 Corporate Sponsorship Texas Osteopathic Medical $3,000.00 Corporate Sponsorship Association Texas Urological Socty $4,500.00 Corporate Sponsorship Texas Urological Socty $4,500.00 Corporate Sponsorship The Endocrine Socty $25,000.00 Educational Grants The Endocrine Socty $25,000.00 Educational Grants The Endocrine Socty $25,000.00 Educational Grants The International Psoriasis $25,000.00 Educational Grants Council Trinity Christian Colg Asoc $1,000.00 Charitable Donations Trustees of The Univ of $10,000.00 Educational Grants Pennsylvania Tufts Med Ctr $2,500.00 Corporate Sponsorship Tufts Univ ($4,580.00) Educational Grants Tulane Univ Hlth Scnc Ctr $20,000.00 Corporate Sponsorship UC Regents Maxillofacial $20,000.00 Educational Grants Prosthetics Clnc UC Regents Maxillofacial $10,000.00 Educational Grants Prosthetics Clnc UC Regents Maxillofacial $40,000.00 Fellowships and Prosthetics Clnc Scholarships UC Regents Maxillofacial $5,000.00 Educational Grants Prosthetics Clnc UC Regents Maxillofacial $15,000.00 Educational Grants Prosthetics Clnc Ultimate Med Academy Med $150,000.00 Educational Grants Learning Grp LLC Ultimate Med Academy Med $198,790.00 Educational Grants Learning Grp LLC Ultimate Med Academy Med $98,600.00 Educational Grants Learning Grp LLC Ultimate Med Academy Med $389,100.00 Educational Grants Learning Grp LLC UMA Education Inc. DBA $90,000.00 Educational Grants Global Education Grp Umass Amherst $5,000.00 Corporate Sponsorship Umass Fdtn $2,500.00 Charitable Donations United Spinal Association $75,000.00 Corporate Sponsorship Inc. United States Adult Cystic $7,500.00 Educational Grants Fibrosis Asoc Inc. United Way of Ctrl $1,250.00 Corporate Sponsorship Massachusetts United Way of Ctrl $5,000.00 Corporate Sponsorship Massachusetts Univ Connecticut Derm $12,000.00 Fellowships and Scholarships Univ Connecticut Derm ($130.91) Fellowships and Scholarships Univ Hlth Srvc At Stony $20,000.00 Educational Grants Point Inc. Univ Hosp Cleveland Med $15,000.00 Fellowships and Scholarships Univ Hosp of Brooklyn $16,000.00 Educational Grants Univ of Alabama At $8,000.00 Educational Grants Birmingham Univ of Alabama At $40,000.00 Fellowships and Birmingham Scholarships Univ of California--San $50,000.00 Fellowships and Francisco Scholarships Univ of California--San $5,000.00 Educational Grants Francisco Univ of California--San $10,000.00 Educational Grants Francisco Univ of California Berkeley $20,000.00 Educational Grants Univ of California Berkeley $45,000.00 Corporate Sponsorship Univ of California Berkeley $50,000.00 Corporate Sponsorship Univ of California Irvine $5,000.00 Fellowships and Scholarships Univ of California Irvine $5,000.00 Educational Grants Univ of Chicago $10,000.00 Charitable Donations Univ of Chicago $10,000.00 Educational Grants Univ of Cincinnati $85,000.00 Educational Grants Univ of Cincinnati $75,000.00 Educational Grants Univ of Cincinnati $60,000.00 Educational Grants Univ of Cincinnati $250,000.00 Educational Grants Univ of Cincinnati $130,000.00 Educational Grants Univ of Cincinnati $30,000.00 Educational Grants Univ of Colorado Denver $3,500.00 Educational Grants School of Medicine Univ of Florida $15,898.00 Educational Grants Univ of Florida $75,000.00 Educational Grants Univ of Florida Fdtn $500.00 Corporate Sponsorship Univ of Florida Fdtn $40,000.00 Fellowships and Scholarships Univ of Illinios $40,000.00 Fellowships and Scholarships Univ of Illinois Fdtn $1,000.00 Charitable Donations Univ of Illinois Fdtn $1,000.00 Charitable Donations Univ of Kansas Hosp $50,000.00 Fellowships and Scholarships Univ of Kansas Hosp $45,000.00 Educational Grants Univ of Louisville Research $75,000.00 Educational Grants Fdtn Univ of Louisville Research $15,000.00 Educational Grants Fdtn Univ of Louisville Research $5,000.00 Educational Grants Fdtn Univ of Louisville Research $1,500.00 Educational Grants Fdtn Univ of Maryland Baltimore $5,000.00 Fellowships and Scholarships Univ of Maryland Baltimore $1,000.00 Charitable Donations Fdtn Univ of Massachusetts Med $1,000.00 Charitable Donations School Univ of Massachusetts Med $2,500.00 Educational Grants School Univ of Minnesota Regents $1,500.00 Educational Grants Univ of Minnesota Regents $1,000.00 Educational Grants Univ of Nebraska Med Ctr $20,000.00 Educational Grants Univ of Nebraska Med Ctr $7,500.00 Educational Grants ------------------------------------------------------------------------ Grants Donations Report--2017 (Parentheses represent refunds of previously disclosed payments) Report as of 3/31/2018 ------------------------------------------------------------------------ Recipient Payment Amount Purpose ------------------------------------------------------------------------ 50 Hoops $10,000.00 Educational Grants A and R Educational Group $4,500.00 Corporate Sponsorships LLC A and R Educational Group $20,000.00 Corporate Sponsorships LLC Academia Medica Del Sur $8,000.00 Corporate Sponsorships Academia Puertorriquena DE $3,000.00 Corporate Sponsorships Neurologia Academy of Managed Care $25,000.00 Corporate Sponsorships Pharmacy Academy of Managed Care $15,000.00 Corporate Sponsorships Pharmacy Academy of Physician $2,500.00 Corporate Sponsorships Assistants, Tennessee Advanced Urology Institute $10,000.00 Corporate Sponsorships Education and General Fund Advances in Cosmetic and $75,000.00 Corporate Sponsorships Med Dermatology Inc. Advances in Cosmetic and $100,000.00 Corporate Sponsorships Med Dermatology Inc. Advances in Cosmetic and $75,000.00 Corporate Sponsorships Med Dermatology Inc. Advocate Bromenn Medical $2,000.00 Educational Grants Center Advocate Bromenn Medical $2,500.00 Educational Grants Center Aesthetic Dermatology $35,000.00 Corporate Sponsorships Symposia Aesthetic Dermatology $25,000.00 Corporate Sponsorships Symposia AIDS Connecticut $2,500.00 Corporate Sponsorships AIDS Connecticut $2,500.00 Corporate Sponsorships AIDS Foundation of Chicago $25,000.00 Charitable Donations AIDS Institute $36,000.00 Corporate Sponsorships Alabama Dermatology Society $50,000.00 Corporate Sponsorships Alabama Dermatology Society $50,000.00 Corporate Sponsorships Alaska Rheumatology $5,000.00 Corporate Sponsorships Alliance Alliance for Aging Research $5,000.00 Corporate Sponsorships Alliance for Patient Access $30,000.00 Corporate Sponsorships Alzheimers Association $10,000.00 Corporate Sponsorships Greater Illinois Chapter Alzheimers Association $2,500.00 Corporate Sponsorships Greater Illinois Chapter Alzheimers Association $5,000.00 Corporate Sponsorships Greater Illinois Chapter Alzheimers Disease and $133,750.00 Corporate Sponsorships Related Disorders Association Inc. American Academy of $50,000.00 Charitable Donations Dermatology American Academy of $65,000.00 Corporate Sponsorships Dermatology American Academy of $35,000.00 Corporate Sponsorships Dermatology American Academy of $25,000.00 Charitable Donations Dermatology American Academy of $40,000.00 Educational Grants Dermatology American Academy of $25,000.00 Corporate Sponsorships Dermatology American Academy of $15,000.00 Charitable Donations Dermatology American Academy of $37,500.00 Corporate Sponsorships Dermatology American Academy of $50,000.00 Educational Grants Dermatology American Academy of $300,000.00 Corporate Sponsorships Dermatology American Academy of Family $17,000.00 Educational Grants Physicians American Academy of $75,000.00 Corporate Sponsorships Neurology Institute American Academy of $30,000.00 Educational Grants Neurology Institute American Academy of $53,400.00 Corporate Sponsorships Neurology Institute American Academy of $50,000.00 Fellowships and Neurology Institute Scholarships American Academy of $30,000.00 Corporate Sponsorships Neurology Institute American Academy of $14,000.00 Corporate Sponsorships Pediatrics American Academy of $10,000.00 Educational Grants Physician Assistants American Academy of $16,000.00 Educational Grants Physician Assistants American Association of $20,000.00 Corporate Sponsorships Clinical Endocrinologists New Jersey Chapter American Association of $18,000.00 Educational Grants Clinical Endocrinologists New Jersey Chapter American Association of $10,000.00 Corporate Sponsorships Physicians of Indian Origin Arkansas American Association of $10,000.00 Corporate Sponsorships Physicians of Indian Origin Arkansas American Association for ($2,205.00) Educational Grants Accreditation of Laboratory Animal Care International American Association for $25,000.00 Fellowships and Cancer Research Scholarships American Association for $25,000.00 Educational Grants Cancer Research American Association for $25,000.00 Educational Grants Cancer Research American Association for $10,000.00 Educational Grants Cancer Research American Association for $25,000.00 Charitable Donations Cancer Research American Association for $10,000.00 Educational Grants Cancer Research American Association for $25,000.00 Educational Grants Cancer Research American Association for $25,000.00 Educational Grants Cancer Research American Association for $15,000.00 Educational Grants Cancer Research American Association for $15,000.00 Educational Grants Cancer Research American Association for $15,000.00 Educational Grants Cancer Research American Association for $15,000.00 Educational Grants Cancer Research American Association for $75,000.00 Educational Grants Cancer Research American Association for $20,000.00 Charitable Donations Laboratory Animal Science American Association for $5,000.00 Educational Grants Laboratory Animal Science New England Branch American Association for $3,150.00 Corporate Sponsorships The Study of Liver Disease American Association of $7,400.00 Corporate Sponsorships Gynecologic Laparoscopists Inc American Association of $59,500.00 Corporate Sponsorships Gynecologic Laparoscopists Inc American Association of $50,000.00 Corporate Sponsorships Pharmaceutical Scientists American Autoimmune Related $40,000.00 Corporate Sponsorships American Brain Tumor $30,000.00 Educational Grants Association American Brain Tumor $10,000.00 Educational Grants Association American Brain Tumor $15,000.00 Educational Grants Association American Brain Tumor $15,000.00 Corporate Sponsorships Association American Brain Tumor $7,500.00 Corporate Sponsorships Association American Cancer Society $10,000.00 Corporate Sponsorships American Cancer Society $1,500.00 Corporate Sponsorships American Cancer Society $3,500.00 Corporate Sponsorships American Cancer Society $50,000.00 Corporate Sponsorships American Cancer Society $5,000.00 Corporate Sponsorships Action Network Connecticut American Cancer Society $2,500.00 Corporate Sponsorships Action Network North Carolina American Cancer Society $5,000.00 Corporate Sponsorships Cancer Action Network American Cancer Society $5,000.00 Corporate Sponsorships Cancer Action Network American Cancer Society $10,000.00 Corporate Sponsorships Cancer Action Network American Cancer Society $5,000.00 Corporate Sponsorships Cancer Action Network American Cancer Society $2,500.00 Corporate Sponsorships Cancer Action Network American Cancer Society $10,000.00 Corporate Sponsorships Cancer Action Network American Cancer Society $5,000.00 Corporate Sponsorships Cancer Action Network American Cancer Society $2,500.00 Corporate Sponsorships Cancer Action Network American Cancer Society $3,000.00 Corporate Sponsorships Cancer Action Network American Cancer Society $2,500.00 Corporate Sponsorships Cancer Action Network American Cancer Society $7,500.00 Corporate Sponsorships Cancer Action Network American Cancer Society $2,500.00 Corporate Sponsorships Cancer Action Network American Cancer Society $2,500.00 Corporate Sponsorships Cancer Action Network American Cancer Society $7,000.00 Corporate Sponsorships Cancer Action Network American Cancer Society $10,000.00 Corporate Sponsorships Cancer Action Network American Cancer Society $3,000.00 Corporate Sponsorships Cancer Action Network American Cancer Society $25,000.00 Corporate Sponsorships Cancer Action Network American Cancer Society $2,500.00 Corporate Sponsorships Cancer Action Network American Chemist Society $2,500.00 Educational Grants American Chemist Society $1,000.00 Educational Grants American Chemist Society $3,000.00 Educational Grants American College of Chest $35,000.00 Educational Grants Physicians American College of $5,000.00 Educational Grants Clinical Pharmacology American College of $10,000.00 Patient Support Endocrinology American College of $15,000.00 Educational Grants Gastroenterology American College of $100,000.00 Corporate Sponsorships Gastroenterology American College of $90,000.00 Corporate Sponsorships Gastroenterology American College of $30,000.00 Charitable Donations Laboratory Animal Medicine American College of $5,000.00 Educational Grants Obstetricians and Gynecologists American College of $15,000.00 Corporate Sponsorships Osteopathic Obstetricians and Gynecologists American College of $15,000.00 Corporate Sponsorships Osteopathic Obstetricians and Gynecologists American College of $57,000.00 Corporate Sponsorships Physician Foundation American College of $1,000.00 Corporate Sponsorships Physicians West Virginia Chapter American College of $10,000.00 Corporate Sponsorships Rheumatology American College of $80,000.00 Fellowships and Rheumatology Scholarships American College of $25,000.00 Educational Grants Rheumatology American College of $20,000.00 Educational Grants Rheumatology American College of $37,500.00 Educational Grants Rheumatology American College of $17,600.00 Educational Grants Rheumatology American College of $150,000.00 Corporate Sponsorships Rheumatology American College of $2,000,000.00 Corporate Sponsorships Rheumatology Research and Education Foundation American College of $500,000.00 Corporate Sponsorships Rheumatology Research and Education Foundation American Congress of $10,500.00 Corporate Sponsorships Obstetricians and Gynecologists American Congress of $12,500.00 Corporate Sponsorships Obstetricians and Gynecologists American Congress of $12,500.00 Corporate Sponsorships Obstetricians and Gynecologists American Congress of $12,500.00 Corporate Sponsorships Obstetricians and Gynecologists American Congress of $13,250.00 Corporate Sponsorships Obstetricians and Gynecologists American Congress of $50,000.00 Educational Grants Obstetricians and Gynecologists American Congress of $5,000.00 Educational Grants Obstetricians and Gynecologists American $12,500.00 Charitable Donations Gastroenterological Association Institute American $5,000.00 Corporate Sponsorships Gastroenterological Association Institute American $40,000.00 Educational Grants Gastroenterological Association Institute American $75,000.00 Educational Grants Gastroenterological Association Institute American Kidney Fund $5,000.00 Corporate Sponsorships American Legion National $25,000.00 Corporate Sponsorships American Liver Foundation $275,000.00 Corporate Sponsorships American Liver Foundation $25,000.00 Corporate Sponsorships American Liver Foundation $10,000.00 Corporate Sponsorships American Liver Foundation $5,000.00 Educational Grants American Liver Foundation $5,000.00 Educational Grants American Liver Foundation $2,500.00 Corporate Sponsorships American Liver Foundation $1,000.00 Corporate Sponsorships American Liver Foundation $2,500.00 Corporate Sponsorships American Liver Foundation $2,500.00 Corporate Sponsorships American Liver Foundation $1,500.00 Corporate Sponsorships American Lung Association $100,000.00 Corporate Sponsorships American Lung Association $5,000.00 Corporate Sponsorships of The Northeast American Lung Association $5,000.00 Corporate Sponsorships of The Northeast American Lung Association $7,500.00 Corporate Sponsorships of The Northeast American Med Group $10,000.00 Corporate Sponsorships Associate American Med Group $10,000.00 Corporate Sponsorships Associate American Med Group $20,000.00 Corporate Sponsorships Associate American Med Group $4,940.00 Corporate Sponsorships Associate American Med Group $4,940.00 Corporate Sponsorships Associate American Med Group $4,940.00 Corporate Sponsorships Associate American Med Group $4,940.00 Corporate Sponsorships Associate American Med Group $4,940.00 Corporate Sponsorships Associate American Med Group $4,940.00 Corporate Sponsorships Associate American Med Group $4,940.00 Corporate Sponsorships Associate American Med Group $4,940.00 Corporate Sponsorships Associate American Med Group $4,940.00 Corporate Sponsorships Associate American Med Group $4,940.00 Corporate Sponsorships Associate American Neuro Associate $40,000.00 Educational Grants American Pancreatic $25,000.00 Patient Support Associate American Pancreatic $75,000.00 Educational Grants Associate American Parkinson Disease $20,000.00 Educational Grants Association American Parkinson Disease $3,500.00 Corporate Sponsorships Association American Parkinson Disease $62,000.00 Corporate Sponsorships Association American Parkinson Disease $5,500.00 Corporate Sponsorships Association American Parkinson Disease $3,000.00 Corporate Sponsorships Association American Parkinson Disease $2,500.00 Corporate Sponsorships Association American Parkinson Disease $5,000.00 Corporate Sponsorships Association American Red Cross of $10,000.00 Charitable Donations Greater Chicago American Society for $2,000.00 Educational Grants Pharmacology and Experimental Therapeutics American Society for $10,000.00 Corporate Sponsorships Reproductive Medicine American Society for $3,000.00 Corporate Sponsorships Reproductive Medicine American Society for $15,000.00 Corporate Sponsorships Reproductive Medicine American Society of Colon $35,000.00 Educational Grants and Rectal Surgns American Society of $50,000.00 Fellowships and Hematology Scholarships American Society of $20,000.00 Educational Grants Hematology American Society of $60,000.00 Educational Grants Hematology American Society of $50,000.00 Educational Grants Hematology American Society of Nphro $35,000.00 Corporate Sponsorships American Society of Nphro $160,000.00 Educational Grants American Statistical $2,000.00 Educational Grants Associate American Statistical $2,500.00 Educational Grants Associate American Thyroid Associate $30,000.00 Educational Grants Inc. American Urological $50,000.00 Charitable Donations Associate Education and Research Inc. American Urological $20,000.00 Educational Grants Associate Education and Research Inc. American Urological $50,000.00 Educational Grants Associate Education and Research Inc. American Urological $50,000.00 Educational Grants Associate Education and Research Inc. American Urological $13,500.00 Corporate Sponsorships Associate Inc Western Section American Urological $25,000.00 Charitable Donations Association American Urological $6,000.00 Corporate Sponsorships Association American Urological $2,000.00 Corporate Sponsorships Association American Urological $10,000.00 Corporate Sponsorships Association American Urological $6,000.00 Corporate Sponsorships Association American Urological $10,000.00 Charitable Donations Association American Urological $6,000.00 Corporate Sponsorships Association American Urological $1,500.00 Corporate Sponsorships Association Americans for Med Progress $90,000.00 Charitable Donations Americares Foundation $12,000.00 Charitable Donations American Hepato-Pancreato- $30,000.00 Corporate Sponsorships Biliary Association Angel Foundation $2,500.00 Corporate Sponsorships Arizona State Association $3,500.00 Corporate Sponsorships of Physician Assistants Arizona United Rheumatology $25,000.00 Corporate Sponsorships Alliance--Aura Arkansas State Rheumatology $10,000.00 Corporate Sponsorships Association Inc. Arkansas Technology $1,000.00 Charitable Donations University Foundation Arthritis Foundation $5,000.00 Charitable Donations Arthritis Foundation $5,000.00 Educational Grants Arthritis Foundation $2,000.00 Corporate Sponsorships Arthritis Foundation $30,000.00 Corporate Sponsorships Arthritis Foundation $10,000.00 Corporate Sponsorships Arthritis Foundation $4,000.00 Educational Grants Arthritis Foundation $5,000.00 Educational Grants Arthritis Foundation $20,000.00 Educational Grants Arthritis Foundation $20,000.00 Educational Grants Arthritis Foundation $3,000.00 Educational Grants Arthritis Foundation $50,000.00 Corporate Sponsorships Arthritis Foundation $2,500.00 Educational Grants Arthritis Foundation $2,500.00 Corporate Sponsorships Arthritis Foundation $3,000.00 Corporate Sponsorships Arthritis Foundation $10,000.00 Corporate Sponsorships Arthritis Foundation $2,500.00 Corporate Sponsorships Arthritis Foundation $3,000.00 Corporate Sponsorships Arthritis Foundation $2,000.00 Corporate Sponsorships Arthritis Foundation $50,000.00 Corporate Sponsorships Arthritis Foundation $5,000.00 Educational Grants Arthritis Foundation $250,000.00 Corporate Sponsorships Arthritis Foundation $300,000.00 Corporate Sponsorships Arthritis Foundation $300,000.00 Corporate Sponsorships Arthritis Foundation $259,000.00 Corporate Sponsorships Arthritis Foundation Inc. $50,000.00 Corporate Sponsorships Arthritis Patient Services $2,400.00 Educational Grants Arthritis Patient Services $5,000.00 Educational Grants Arthritis Patient Services $65,000.00 Educational Grants ARVO Foundation for Eye $5,000.00 Fellowships and Research Scholarships ASCO Cancer Foundation $100,000.00 Patient Support ASCO Cancer Foundation $20,000.00 Educational Grants ASCO Cancer Foundation $28,000.00 Educational Grants ASCO Cancer Foundation $10,000.00 Educational Grants ASCO Cancer Foundation $10,000.00 Educational Grants ASCO Cancer Foundation $15,000.00 Educational Grants ASCO Cancer Foundation $15,000.00 Educational Grants ASCO Cancer Foundation $15,000.00 Educational Grants ASCO Cancer Foundation $30,000.00 Educational Grants ASCO Cancer Foundation $30,000.00 Educational Grants ASCO Cancer Foundation $30,000.00 Educational Grants ASCO Cancer Foundation $56,000.00 Educational Grants ASCO Cancer Foundation $60,000.00 Educational Grants ASCO Cancer Foundation $75,000.00 Educational Grants ASCO Cancer Foundation $34,500.00 Corporate Sponsorships ASCO Cancer Foundation $13,275.00 Educational Grants ASCO Cancer Foundation $26,000.00 Educational Grants Asembia $60,000.00 Corporate Sponsorships ASHP Foundation $75,000.00 Fellowships and Scholarships Associate DE $10,000.00 Corporate Sponsorships Gastroenterologia Y Hepatologia Pediatrica DE Puerto Rico Aghppr Associate DE Reumatologos $7,500.00 Corporate Sponsorships DE Puerto Rico Associate DE Reumatologos $15,000.00 Corporate Sponsorships DE Puerto Rico Associate of Physician $25,000.00 Corporate Sponsorships Assistants in Oncology Inc. Associate of Physician $7,500.00 Corporate Sponsorships Assistants in Oncology Inc. Associate of Physician $7,500.00 Corporate Sponsorships Assistants in Oncology Inc. Associate of Professors of $50,000.00 Corporate Sponsorships Gyn and Obstetrician Associate of Professors of $5,000.00 Corporate Sponsorships Gyn and Obstetrician Associate of Professors of $75,000.00 Educational Grants Gyn and Obstetrician Associate of Reproductive $50,000.00 Educational Grants Health Professionals Associate of Univ $5,000.00 Corporate Sponsorships Technology Managers Association of Community $15,000.00 Corporate Sponsorships Cancer Centers (ACCC) Association of Community $150,000.00 Corporate Sponsorships Cancer Centers (ACCC) Association of Women in $40,000.00 Corporate Sponsorships Rheumatology Association of Women in $30,000.00 Corporate Sponsorships Rheumatology Association of Women in $75,000.00 Corporate Sponsorships Rheumatology Atlanta Dermatology and $10,000.00 Corporate Sponsorships Pathology Associates, PC Autoimmune Advocacy $3,000.00 Corporate Sponsorships Alliance Auxiliary of Robert Wood $5,000.00 Corporate Sponsorships Johnson University Hospital Baehr Challenge Ltd $1,000.00 Corporate Sponsorships Ball State University $1,000.00 Charitable Donations Foundation Baylor College Medicine $5,000.00 Educational Grants Infusion Dis Baylor College Medicine $3,600.00 Fellowships and Infusion Dis Scholarships Baylor Health Care System $40,000.00 Fellowships and Foundation Scholarships Baylor Scott and White $5,000.00 Educational Grants Health Baylor Scott and White $30,000.00 Educational Grants Health Bendcare $410,000.00 Corporate Sponsorships Beth Israel Deaconess ($16,526.70) Educational Grants Medical Center Beth Israel Deaconess $40,000.00 Fellowships and Medical Center Scholarships Beth Israel Deaconess $30,000.00 Fellowships and Medical Center Scholarships Beth Israel Deaconess $35,000.00 Fellowships and Medical Center Scholarships Beth Israel Deaconess $40,000.00 Fellowships and Medical Center Scholarships Beth Israel Deaconess $3,000.00 Educational Grants Medical Center Beth Israel Deaconess ($1,751.70) Educational Grants Medical Center Beth Israel Med Center $25,000.00 Fellowships and Scholarships Bioconnections LLC $50,000.00 Corporate Sponsorships Biotechnology Industry $8,000.00 Corporate Sponsorships Organization Board of Trustees of The $3,000.00 Corporate Sponsorships Leland Stanford Junior Univ Board of Trustees of The $1,500.00 Educational Grants Univ of Illinois Bonnie J Addario Lung $5,000.00 Corporate Sponsorships Cancer Foundation Bonnie J Addario Lung $25,000.00 Corporate Sponsorships Cancer Foundation Boomer Esiason Foundation $25,000.00 Corporate Sponsorships Borland Groover Clinic $1,000.00 Corporate Sponsorships Borland Groover Clinic $750.00 Corporate Sponsorships Borland Groover Clinic $1,000.00 Corporate Sponsorships Boston College School of $7,500.00 Corporate Sponsorships Nursing Boston Society Inc. $3,000.00 Educational Grants Boston Taiwanese $2,500.00 Educational Grants Biotechnology Association Inc. Brain Support Network Inc. $5,000.00 Educational Grants Breast Friends $1,000.00 Corporate Sponsorships Breastcancer.Org $5,000.00 Educational Grants Brian Grant Foundation $150,000.00 Educational Grants Brian Grant Foundation $1,500.00 Corporate Sponsorships Brigham and Women's $7,000.00 Educational Grants Hospital, Inc. Brigham and Women's $40,000.00 Fellowships and Hospital, Inc. Scholarships Broad Institute $5,000.00 Corporate Sponsorships California Associate of $3,500.00 Corporate Sponsorships Physician Groups California Associate of $25,000.00 Corporate Sponsorships Physician Groups California Chronic Care $25,000.00 Corporate Sponsorships Coalition California Chronic Care $10,000.00 Corporate Sponsorships Coalition California Life Sciences $5,000.00 Corporate Sponsorships Association California Life Sciences $5,500.00 Corporate Sponsorships Association California Neurology $5,000.00 Educational Grants Society California Neurology $5,000.00 Educational Grants Society California Society of $10,000.00 Corporate Sponsorships Dermatology and Dermatology Surgry California Society of $10,000.00 Corporate Sponsorships Dermatology and Dermatology Surgry California Society of $10,000.00 Corporate Sponsorships Dermatology and Dermatology Surgry Cancer and Leukemia Group B $50,000.00 Educational Grants Foundation Cancer and Leukemia Group B $30,000.00 Educational Grants Foundation Cancer and Leukemia Group B $50,000.00 Educational Grants Foundation Cancer Awareness of Nevada $1,000.00 Corporate Sponsorships Cancer Care $10,000.00 Educational Grants Cancer Care $50,000.00 Charitable Donations Cancer Care $15,000.00 Educational Grants Cancer Care $25,000.00 Educational Grants Cancer Care $100,000.00 Corporate Sponsorships Cancer Care $150,000.00 Educational Grants Cancer Care $150,000.00 Educational Grants Cancer Care $90,000.00 Educational Grants Cancer Care $50,000.00 Educational Grants Cancer Care $100,000.00 Educational Grants Cancer Care $65,000.00 Corporate Sponsorships Cancer Molecular Thrpt $5,000.00 Educational Grants Cancer Support Community $75,000.00 Educational Grants Cancer Support Community $25,000.00 Educational Grants Cancer Support Community $50,000.00 Educational Grants Cancer Wellness Center $5,000.00 Corporate Sponsorships Cardinal Health $170,000.00 Corporate Sponsorships Cardinal Health $60,000.00 Corporate Sponsorships Caribe Gyn $5,000.00 Corporate Sponsorships Caribe Gyn $17,000.00 Corporate Sponsorships Caring Ambassadors Program $75,000.00 Charitable Donations Inc. Caring Ambassadors Program $15,000.00 Patient Support Inc. Carti Foundation $10,000.00 Corporate Sponsorships Cascade AIDS Project $5,000.00 Corporate Sponsorships Cedars--Sinai Med Center $40,000.00 Fellowships and Scholarships Cedars--Sinai Med Center $10,000.00 Educational Grants Central Brain Tumor $25,000.00 Educational Grants Registry of The United States Central Brain Tumor $25,000.00 Educational Grants Registry of The United States Central Savannah River Area $1,000.00 Corporate Sponsorships Csra Parkinson Support Group Chicago Urological Soctiey $12,000.00 Corporate Sponsorships Childrens Hospital Corp $5,000.00 Educational Grants Childrens Hospital of $10,000.00 Corporate Sponsorships Philadelphia Childrens Treehouse $10,000.00 Patient Support Foundation Chimp Haven $20,000.00 Charitable Donations Chinese American Society of $5,000.00 Corporate Sponsorships Nuclear Medicine and Molecular Imaging Chris Elliott Fund $10,000.00 Charitable Donations Chris Elliott Fund $10,000.00 Charitable Donations Chris Elliott Fund $10,000.00 Charitable Donations Chris Elliott Fund $5,000.00 Charitable Donations Chris Elliott Fund $5,000.00 Charitable Donations Chronic Liver Disease $50,000.00 Corporate Sponsorships Foundation Chronic Liver Disease $300,000.00 Educational Grants Foundation Chronic Liver Disease $200,000.00 Educational Grants Foundation Chronic Liver Disease $247,350.00 Educational Grants Foundation Chronic Liver Disease $226,945.00 Educational Grants Foundation Chronic Liver Disease $25,000.00 Corporate Sponsorships Foundation Chronic Lymphocytic $75,000.00 Corporate Sponsorships Leukemia Society Inc. Chronic Lymphoytic Leukemia $22,825.00 Educational Grants Society Inc. Chronic Lymphoytic Leukemia $50,000.00 Charitable Donations Society Inc. Chronic Lymphoytic Leukemia $75,000.00 Educational Grants Society Inc. Chronic Lymphoytic Leukemia $50,000.00 Educational Grants Society Inc. Chronic Lymphoytic Leukemia $50,000.00 Educational Grants Society Inc. Cincinnati Childrens $40,000.00 Fellowships and Hospital Medical Center Scholarships Cincinnati Childrens $25,000.00 Corporate Sponsorships Hospital Medical Center City of Hope National Med $5,000.00 Corporate Sponsorships Center Cleveland Clinic $65,000.00 Educational Grants Cleveland Clinic $65,000.00 Educational Grants Cleveland Clinic $5,000.00 Educational Grants Cleveland Clinic $10,000.00 Corporate Sponsorships Cleveland Clinic $50,000.00 Educational Grants Cleveland Clinic $20,000.00 Corporate Sponsorships Cleveland Clinic $5,000.00 Educational Grants Cleveland Clinic $55,000.00 Fellowships and Scholarships Cleveland Clinic $40,000.00 Fellowships and Scholarships Cleveland Clinic ($4,853.56) Educational Grants Educational Foundation Cleveland Clinic $5,000.00 Educational Grants Educational Foundation Cleveland Clinic $15,000.00 Educational Grants Educational Foundation Cleveland Clinic $5,000.00 Educational Grants Educational Foundation Cleveland Clinic $2,500.00 Educational Grants Educational Foundation Cleveland Clinic $5,000.00 Educational Grants Educational Foundation Cleveland Clinic $5,000.00 Educational Grants Educational Foundation Cleveland Clinic $15,000.00 Educational Grants Educational Foundation Cleveland Clinic ($6,652.23) Educational Grants Educational Foundation Cleveland Clinic ($5,410.94) Educational Grants Educational Foundation Cleveland Clinic $65,000.00 Educational Grants Educational Foundation Cleveland Clinic Minority $40,000.00 Fellowships and Mens Health Center Scholarships Clinical Care Optn LLC $50,000.00 Educational Grants Clinical Care Optn LLC $50,000.00 Educational Grants Clinical Care Optn LLC $60,000.00 Educational Grants Clinical Care Optn LLC $25,000.00 Educational Grants Clinical Care Optn LLC $95,560.00 Educational Grants Clinical Care Optn LLC $25,000.00 Educational Grants Clinical Care Optn LLC $75,000.00 Educational Grants Clinical Care Optn LLC $95,000.00 Educational Grants Clinical Care Optn LLC $150,000.00 Educational Grants Cll Global Research $35,000.00 Educational Grants Foundation Cll Global Research $20,000.00 Educational Grants Foundation Cll Global Research $35,000.00 Educational Grants Foundation Coalition for Prevention of $10,000.00 Corporate Sponsorships Colorectal Cancer in Puerto Rico Coalition of Positive $40,000.00 Educational Grants Health Empowerment Coalition of Texans With $5,000.00 Corporate Sponsorships Disabilities Coalition On Positive $5,000.00 Corporate Sponsorships Health Empower Cockerell Educational $25,000.00 Corporate Sponsorships Foundation Cody Dieruf Benefit $5,000.00 Patient Support Foundation Cold Spring Harbor $2,500.00 Educational Grants Laboratory Collaborative Alliance for $6,000.00 Fellowships and Pancreatic Education and Scholarships Research Collaborative Alliance for $30,000.00 Educational Grants Pancreatic Education and Research Collaborative Alliance for $1,750.00 Corporate Sponsorships Pancreatic Education and Research Colorado Gerontological $5,000.00 Corporate Sponsorships Society Columbia Univ Med Center $5,000.00 Educational Grants Community Access National $2,500.00 Corporate Sponsorships Network Community Center $15,000.00 Corporate Sponsorships Community Center $10,000.00 Corporate Sponsorships Community Foundation $5,000.00 Corporate Sponsorships Community Foundation $5,000.00 Corporate Sponsorships Community Initiatives $150,000.00 Corporate Sponsorships Community Initiatives $30,000.00 Corporate Sponsorships Community Initiatives $25,000.00 Corporate Sponsorships Community Liver Alliance $20,000.00 Corporate Sponsorships Community Liver Alliance $5,000.00 Corporate Sponsorships Community Liver Alliance $9,000.00 Corporate Sponsorships Community Liver Alliance $3,000.00 Corporate Sponsorships Community Liver Alliance $5,000.00 Corporate Sponsorships Complex Mechanisms of $1,500.00 Educational Grants Disease Aging and Trauma (Cmdat) Research Foundation Connecticut Advanced Nurse $2,000.00 Corporate Sponsorships Practitioner Society Connecticut Advocates for $2,500.00 Corporate Sponsorships Parkinsons Connecticut Peer Review $3,000.00 Corporate Sponsorships Organization--Qualidigm Connecting To Cure Crohns $10,000.00 Corporate Sponsorships and Colitis Consortium of Multiple $50,000.00 Educational Grants Sclerosis Centers Consortium of Multiple $55,000.00 Educational Grants Sclerosis Centers Consortium of Multiple $85,000.00 Educational Grants Sclerosis Centers Continuing Educational $95,000.00 Educational Grants Alliance LLC Continuing Educational $149,000.00 Educational Grants Alliance LLC Continuing Educational $99,550.00 Educational Grants Alliance LLC Continuing Educational ($1,050.00) Educational Grants Alliance LLC Continuing Educational $200,000.00 Educational Grants Alliance LLC Continuing Educational $121,165.00 Educational Grants Alliance LLC Continuing Med Education $85,000.00 Educational Grants Outfitters LLC Cornell Univ Weill Med $15,000.00 Educational Grants College Cornell Univ Weill Med $3,000.00 Educational Grants College Cornerstone Health $3,000.00 Corporate Sponsorships Enablement Strategic Solutions, LLC Cornerstone Health Inc. $75,000.00 Educational Grants Cornerstone Health Inc. $50,000.00 Educational Grants Cradles To Crayons Inc. $300.00 Charitable Donations Creighton Univ $15,000.00 Educational Grants Crohns and Colitis $25,000.00 Charitable Donations Foundation of America Crohns and Colitis $25,000.00 Educational Grants Foundation of America Crohns and Colitis $60,000.00 Educational Grants Foundation of America Crohns and Colitis $80,000.00 Educational Grants Foundation of America Crohns and Colitis $200,000.00 Educational Grants Foundation of America Crohns and Colitis $3,500.00 Corporate Sponsorships Foundation of America Crohns and Colitis $5,000.00 Corporate Sponsorships Foundation of America Crohns and Colitis $1,500.00 Corporate Sponsorships Foundation of America Crohns and Colitis $3,000.00 Corporate Sponsorships Foundation of America Crohns and Colitis $5,000.00 Corporate Sponsorships Foundation of America Crohns and Colitis $12,500.00 Corporate Sponsorships Foundation of America Crohns and Colitis $14,250.00 Corporate Sponsorships Foundation of America Crohns and Colitis $10,000.00 Corporate Sponsorships Foundation of America Crohns and Colitis $2,500.00 Corporate Sponsorships Foundation of America Crohns and Colitis $1,500.00 Corporate Sponsorships Foundation of America Crohns and Colitis $2,500.00 Corporate Sponsorships Foundation of America Crohns and Colitis $20,000.00 Corporate Sponsorships Foundation of America Crohns and Colitis $2,000.00 Corporate Sponsorships Foundation of America Crohns and Colitis $2,500.00 Corporate Sponsorships Foundation of America Crohns and Colitis $5,000.00 Corporate Sponsorships Foundation of America Crohns and Colitis $2,000.00 Corporate Sponsorships Foundation of America Crohns and Colitis $150,000.00 Corporate Sponsorships Foundation of America Crohns and Colitis $10,000.00 Corporate Sponsorships Foundation of America Crohns and Colitis $1,500.00 Corporate Sponsorships Foundation of America Crohns and Colitis $1,500.00 Corporate Sponsorships Foundation of America Crohns and Colitis $25,000.00 Corporate Sponsorships Foundation of America Crohns and Colitis $1,500.00 Corporate Sponsorships Foundation of America Crohns and Colitis $2,000.00 Corporate Sponsorships Foundation of America Crohns and Colitis $100,000.00 Educational Grants Foundation of America Crohns and Colitis $15,000.00 Fellowships and Foundation of America Scholarships Crohns and Colitis $2,500.00 Corporate Sponsorships Foundation of America Crohns and Colitis $20,000.00 Charitable Donations Foundation of America Crohns and Colitis $2,500.00 Corporate Sponsorships Foundation of America Crohns and Colitis $10,000.00 Educational Grants Foundation of America Crohns and Colitis $150,000.00 Educational Grants Foundation of America Crohns and Colitis $25,000.00 Corporate Sponsorships Foundation of America Crohns and Colitis $85,000.00 Corporate Sponsorships Foundation of America Crohns and Colitis $400,000.00 Corporate Sponsorships Foundation of America Cure Cf $1,000.00 Corporate Sponsorships Curepsp Inc. $30,000.00 Educational Grants Curepsp Inc. $10,000.00 Educational Grants Curepsp Inc. $20,000.00 Corporate Sponsorships Curesearch for Childrens $10,000.00 Charitable Donations Cancer Curesearch for Childrens $15,000.00 Corporate Sponsorships Cancer Cystic Fibrosis Foundation $2,500.00 Corporate Sponsorships Cystic Fibrosis Foundation $5,000.00 Corporate Sponsorships Cystic Fibrosis Foundation $2,500.00 Corporate Sponsorships Cystic Fibrosis Foundation $3,000.00 Corporate Sponsorships Cystic Fibrosis Foundation $2,000.00 Corporate Sponsorships Cystic Fibrosis Foundation $2,000.00 Corporate Sponsorships Cystic Fibrosis Foundation $2,500.00 Corporate Sponsorships Cystic Fibrosis Foundation $1,000.00 Corporate Sponsorships Cystic Fibrosis Foundation $2,000.00 Corporate Sponsorships Cystic Fibrosis Foundation $1,500.00 Corporate Sponsorships Cystic Fibrosis Foundation $1,000.00 Corporate Sponsorships Cystic Fibrosis Foundation $2,500.00 Corporate Sponsorships Cystic Fibrosis Foundation $2,500.00 Corporate Sponsorships Cystic Fibrosis Foundation $9,000.00 Corporate Sponsorships Cystic Fibrosis Foundation $3,500.00 Corporate Sponsorships Cystic Fibrosis Foundation $1,500.00 Corporate Sponsorships Cystic Fibrosis Foundation $1,500.00 Corporate Sponsorships Cystic Fibrosis Foundation $2,500.00 Corporate Sponsorships Cystic Fibrosis Foundation $5,000.00 Corporate Sponsorships Cystic Fibrosis Foundation $3,000.00 Corporate Sponsorships Cystic Fibrosis Foundation $3,000.00 Corporate Sponsorships Cystic Fibrosis Foundation $3,000.00 Corporate Sponsorships Cystic Fibrosis Foundation $1,000.00 Corporate Sponsorships Cystic Fibrosis Foundation $2,500.00 Corporate Sponsorships Cystic Fibrosis Foundation $2,500.00 Corporate Sponsorships Cystic Fibrosis Foundation $2,500.00 Corporate Sponsorships Cystic Fibrosis Foundation $1,000.00 Corporate Sponsorships Cystic Fibrosis Foundation $1,500.00 Corporate Sponsorships Cystic Fibrosis Foundation $250.00 Corporate Sponsorships Cystic Fibrosis Foundation $5,000.00 Corporate Sponsorships Cystic Fibrosis Foundation $5,000.00 Corporate Sponsorships Cystic Fibrosis Foundation $1,000.00 Corporate Sponsorships Cystic Fibrosis Foundation $1,500.00 Corporate Sponsorships Cystic Fibrosis Foundation $2,000.00 Corporate Sponsorships Cystic Fibrosis Foundation $500.00 Corporate Sponsorships Cystic Fibrosis Foundation $2,000.00 Corporate Sponsorships Cystic Fibrosis Foundation $6,500.00 Corporate Sponsorships Cystic Fibrosis Foundation $3,500.00 Corporate Sponsorships Cystic Fibrosis Foundation $5,000.00 Corporate Sponsorships Cystic Fibrosis Foundation $2,000.00 Corporate Sponsorships Cystic Fibrosis Foundation $7,500.00 Corporate Sponsorships Cystic Fibrosis Foundation $750,000.00 Corporate Sponsorships Cystic Fibrosis Research $5,000.00 Corporate Sponsorships Fund Emilys Entourage Cystic Fibrosis Research $10,000.00 Corporate Sponsorships Inc. Cystic Fibrosis Research $10,000.00 Corporate Sponsorships Inc. Cystic Fibrosis Research $10,000.00 Corporate Sponsorships Inc. Cystic Fibrosis Research $3,000.00 Corporate Sponsorships Inc. Cystic Fibrosis Research $5,000.00 Corporate Sponsorships Inc. Cystic Fibrosis Research $7,000.00 Corporate Sponsorships Inc. Cystic Fibrosis Research $18,000.00 Corporate Sponsorships Inc. Cystic Fibrosis Research $10,000.00 Corporate Sponsorships Inc. Danville D Elegance $5,000.00 Corporate Sponsorships Foundation Dava Oncology Lp $25,000.00 Corporate Sponsorships Dava Oncology Lp $10,000.00 Corporate Sponsorships Davis Phinney Foundation $5,000.00 Corporate Sponsorships Davis Phinney Foundation $30,000.00 Educational Grants Davis Phinney Foundation $10,000.00 Corporate Sponsorships Davis Phinney Foundation $30,000.00 Educational Grants Davis Phinney Foundation $2,500.00 Corporate Sponsorships Davis Phinney Foundation $20,000.00 Educational Grants Davis Phinney Foundation $30,000.00 Educational Grants DBC Pri-Med LLC $165,000.00 Corporate Sponsorships Deep South Cancer $10,000.00 Corporate Sponsorships Foundation Deep South Cancer $5,000.00 Corporate Sponsorships Foundation Deep South Cancer $5,000.00 Corporate Sponsorships Foundation Dermatology Education $75,000.00 Corporate Sponsorships Foundation Dermatology Education $75,000.00 Corporate Sponsorships Foundation Dermatology Education $50,000.00 Corporate Sponsorships Foundation Dermatology Education $50,000.00 Corporate Sponsorships Foundation Dermatology Education $50,000.00 Corporate Sponsorships Foundation Dermatology Foundation $135,000.00 Charitable Donations Dermatology Foundation $50,000.00 Corporate Sponsorships Dermatology Univ LLC $75,000.00 Corporate Sponsorships Digestive Disease Week $31,500.00 Corporate Sponsorships Digestive Health Foundation $25,000.00 Corporate Sponsorships Diversity and Leadership $6,000.00 Corporate Sponsorships Inc. Doctor Solomon Carter ($4,919.07) Fellowships and Fuller Mental Health Scholarships Center Donate Life Coalition of $10,000.00 Charitable Donations Michigan Duke Univ $5,000.00 Educational Grants Duke Univ ($16,360.00) Educational Grants Eastern Virginia Medical $5,000.00 Educational Grants School Economic Alliance for $2,500.00 Corporate Sponsorships Michigan Eicosanoid Research $2,500.00 Educational Grants Foundation Eisenhower Desert $25,000.00 Educational Grants Orthopedic Center Eisenhower Desert $250,000.00 Educational Grants Orthopedic Center Eisenhower Desert $50,000.00 Educational Grants Orthopedic Center Eisenhower Desert $85,000.00 Educational Grants Orthopedic Center Eisenhower Desert $25,000.00 Educational Grants Orthopedic Center Eisenhower Desert $30,000.00 Educational Grants Orthopedic Center Eisenhower Desert $50,000.00 Educational Grants Orthopedic Center Eisenhower Desert $500,000.00 Educational Grants Orthopedic Center El Centro Regional Medical $6,000.00 Corporate Sponsorships Center F Elsevier Inc. $50,000.00 Educational Grants Employers Health Coalition $7,500.00 Corporate Sponsorships Endocrine Society $25,000.00 Educational Grants Endocrine Society $50,000.00 Educational Grants Endocrine Society $50,000.00 Corporate Sponsorships Endocrine Society $25,000.00 Educational Grants Endometriosis Foundation of $10,000.00 Charitable Donations America Epilepsy Association of $10,000.00 Corporate Sponsorships Central Florida Epilepsy Foundation $5,000.00 Corporate Sponsorships Escuela DE Medicina DE $10,000.00 Educational Grants Ponce Excellence in Rheumatology $100,000.00 Corporate Sponsorships Education LLC Family Med Center $7,500.00 Corporate Sponsorships Bolingbrook Federation of American $2,000.00 Educational Grants Society for Experimental Biology Faseb Federation of American $5,000.00 Corporate Sponsorships Society for Experimental Biology Faseb Federation of American $2,000.00 Corporate Sponsorships Society for Experimental Biology Faseb Federation of American $5,000.00 Corporate Sponsorships Society for Experimental Biology Faseb Federation of Clinical $20,000.00 Educational Grants Immunology Society Federation of Clinical $25,000.00 Educational Grants Immunology Society Feinstein Institute for Med $150,000.00 Educational Grants Research Florida Cancer Specialists $34,500.00 Corporate Sponsorships Foundation Florida Chapter of America $2,500.00 Corporate Sponsorships Academy of Pediatrics Florida Chapter, American $5,000.00 Corporate Sponsorships College of Phyician Services Florida Hospital Orlando $10,000.00 Corporate Sponsorships Florida Society of $22,600.00 Corporate Sponsorships Dermatology and Dermatologic Surgry Florida Society of $25,500.00 Corporate Sponsorships Dermatology and Dermatologic Surgery Florida Society of $60,000.00 Corporate Sponsorships Dermatology Physician Assistants Inc. Florida Society of $65,000.00 Corporate Sponsorships Dermatology Physician Assistants Inc. Florida Society of $35,000.00 Corporate Sponsorships Rheumatology Florida Society of $2,500.00 Corporate Sponsorships Rheumatology Inc. Florida Society of $3,000.00 Corporate Sponsorships Rheumatology Inc. Focus Med Communications $150,000.00 Corporate Sponsorships Focus Med Communications $5,000.00 Corporate Sponsorships Foster Ocular Immunology $33,000.00 Corporate Sponsorships Society Foundation for Biomedical $50,000.00 Charitable Donations Research Foundation of Consortium of $5,450.00 Fellowships and Multiple Sclerosis Centers Scholarships Cmsc Foundation of Consortium of $32,000.00 Fellowships and Multiple Sclerosis Centers Scholarships Cmsc Free To Breathe $25,000.00 Educational Grants Free To Breathe $50,000.00 Corporate Sponsorships Free To Breathe $40,000.00 Educational Grants Friends of Cancer Research $40,000.00 Corporate Sponsorships Friends of The St Louis $50,000.00 Corporate Sponsorships Univ Liver Center Fundacion Alfredo Ruiz $5,000.00 Corporate Sponsorships Fundacion Daledale Inc. $500.00 Corporate Sponsorships Fundacion Puertorriquena DE $12,500.00 Educational Grants Pacientes Consult Endometriosis Funk Zitiello Foundation $4,000.00 Corporate Sponsorships Gastrointestinal Research $50,000.00 Corporate Sponsorships Foundation Gateway for Cancer Research $10,000.00 Charitable Donations Geneva Foundation $10,000.00 Educational Grants George Washington Univ $5,000.00 Corporate Sponsorships George Washington Univ $5,000.00 Corporate Sponsorships Hospital George Washington Univ $3,000.00 Corporate Sponsorships Hospital George Washington Univ $10,000.00 Corporate Sponsorships Hospital Georgetown Univ $7,000.00 Educational Grants Georgetown Univ $50,000.00 Fellowships and Scholarships Georgia Society of $50,000.00 Corporate Sponsorships Dermatology and Dermatologic Surgery Gildas Club Chicago $10,000.00 Charitable Donations Give for A Smile $1,000.00 Corporate Sponsorships Global Academy for Medical $36,000.00 Corporate Sponsorships Education Global Academy for Medical $15,000.00 Corporate Sponsorships Education Global Academy for Medical $90,000.00 Corporate Sponsorships Education Global Academy for Medical $35,000.00 Corporate Sponsorships Education Global Academy for Medical $58,500.00 Corporate Sponsorships Education Global Academy for Medical $76,500.00 Corporate Sponsorships Education Global Healthy Living $75,000.00 Corporate Sponsorships Foundation Global Healthy Living $75,000.00 Corporate Sponsorships Foundation Global Healthy Living $150,000.00 Corporate Sponsorships Foundation Global Oncology $5,000.00 Corporate Sponsorships Global Resource for $25,000.00 Educational Grants Advancing Cancer Education Global Virus Network Inc. $7,500.00 Educational Grants Global Virus Network Inc. $8,000.00 Educational Grants Good Grief $500.00 Corporate Sponsorships Gordon Research Conferences $2,000.00 Educational Grants Gordon Research Conferences $2,000.00 Educational Grants Gordon Research Conferences $2,000.00 Educational Grants Gordon Research Conferences $2,500.00 Educational Grants Gordon Research Conferences $2,500.00 Educational Grants Gordon Research Conferences $2,500.00 Educational Grants Gordon Research Conferences $3,000.00 Educational Grants Gordon Research Conferences $2,000.00 Educational Grants Gordon Research Conferences $2,500.00 Educational Grants Gordon Research Conferences $2,500.00 Educational Grants Gordon Research Conferences $2,000.00 Educational Grants Gordon Research Conferences $2,500.00 Educational Grants Gordon Research Conferences $2,500.00 Educational Grants Great Lakes Chapter of The $1,000.00 Corporate Sponsorships American Society for Pharmacology and Experimental Therapeutics Group for Research and $15,000.00 Corporate Sponsorships Assessment of Psoriasis and Psoriatic Arthritis Grupo de Apoyo de Ninos y $1,000.00 Corporate Sponsorships Adolescentes Consult Reumatologia Grupo de Apoyo de Ninos y $3,000.00 Corporate Sponsorships Adolescentes Consult Reumatologia Gynecologic Oncology Group $40,000.00 Educational Grants Gynecologic Oncology Group $25,000.00 Educational Grants H Lee Moffitt Cancer Center $5,000.00 Educational Grants and Research Institute H Lee Moffitt Cancer Center $7,500.00 Educational Grants and Research Institute Halo House Foundation $5,000.00 Corporate Sponsorships Harborside Press $38,000.00 Corporate Sponsorships Harborside Press $20,000.00 Corporate Sponsorships Healthcare 21 Business $16,000.00 Corporate Sponsorships Coalition Healthcare 21 Business $1,000.00 Corporate Sponsorships Coalition Healthy Women $30,000.00 Corporate Sponsorships Healthy Women $45,000.00 Corporate Sponsorships Heart to Heart $10,000.00 Charitable Donations International Inc. Heb Grocery Co Lp $7,000.00 Corporate Sponsorships Hematology Oncology $5,000.00 Educational Grants Pharmacy Associate Hematology Oncology $5,000.00 Educational Grants Pharmacy Associate Henry Ford Health System $5,000.00 Educational Grants Henry M Jackson Foundation $10,000.00 Educational Grants Hep C Connection $10,000.00 Corporate Sponsorships Hepatitis C Association $25,000.00 Educational Grants Hepatitis C Association $20,000.00 Educational Grants Hepatitis C Mentor and $10,000.00 Educational Grants Support Group The Hepatitis Education Project $100,000.00 Charitable Donations Hidradenitis Suppurativa $27,500.00 Corporate Sponsorships Foundation Hitchcock Foundation ($2,685.00) Educational Grants Hitchcock Foundation $8,000.00 Educational Grants Hitchcock Foundation $20,000.00 Educational Grants Hitchcock Foundation $8,000.00 Educational Grants HMP Communications $10,000.00 Corporate Sponsorships HMP Communications $60,000.00 Corporate Sponsorships Hope Foundation $40,000.00 Fellowships and Scholarships Hope Foundation $25,000.00 Educational Grants Hospital of the University $60,000.00 Educational Grants of Pennsylvania Hospital of the University $5,000.00 Educational Grants of Pennsylvania Hospital of the University $10,000.00 Educational Grants of Pennsylvania Houston Area Parkinson $5,000.00 Corporate Sponsorships Society Houston Business Coalition $11,000.00 Corporate Sponsorships On Health Howard Brown Health Center $2,500.00 Corporate Sponsorships Howard Hanna Children's $10,000.00 Charitable Donations Free Care Fund Hubbard Street Dance $20,000.00 Educational Grants Chicago Human Growth Foundation $10,000.00 Corporate Sponsorships Human Growth Foundation $10,000.00 Corporate Sponsorships Humboldt--Del Norte County $4,000.00 Educational Grants Medical Society IBD Horizons $80,000.00 Educational Grants IBD Horizons $4,000.00 Corporate Sponsorships IBD Horizons $25,000.00 Corporate Sponsorships IBD Horizons $25,000.00 Corporate Sponsorships IBD Remedy Inc. $5,000.00 Fellowships and Scholarships IBD Remedy Inc. $20,000.00 Patient Support Illinois Cancercare $3,000.00 Corporate Sponsorships Foundation Illinois Society of $40,000.00 Corporate Sponsorships Dermatology Physician Assistants Illinois Society of $20,000.00 Corporate Sponsorships Dermatology Physician Assistants Imedex LLC $200,000.00 Educational Grants Imedex LLC $10,000.00 Educational Grants Imedex LLC $10,000.00 Educational Grants Imedex LLC $50,000.00 Educational Grants Imedex LLC $50,000.00 Educational Grants Imedex LLC $50,000.00 Educational Grants Imedex LLC ($3,596.00) Educational Grants Imedex LLC ($247.00) Educational Grants Imedex LLC $114,000.00 Corporate Sponsorships Imedex LLC $45,750.00 Corporate Sponsorships Impact Education LLC $75,000.00 Educational Grants Indian Doc Associate of $2,500.00 Corporate Sponsorships Houston Indiana Parkinson $2,500.00 Corporate Sponsorships Foundation Indiana Parkinson $2,500.00 Corporate Sponsorships Foundation Indiana Univ $65,000.00 Educational Grants Indiana Univ $10,000.00 Charitable Donations Indiana Urological $5,000.00 Corporate Sponsorships Association Infectious Diseases Society $10,000.00 Educational Grants of America Inflammatory Bowel Disease $50,000.00 Educational Grants Support Foundation Innovation Foundation Inc. $55,000.00 Corporate Sponsorships Integra Life Science $500,000.00 Educational Grants Service Integrated Benefits $25,000.00 Corporate Sponsorships Institute Inc. Integrated Med Foundation $15,000.00 Charitable Donations Integrated Med Foundation $5,000.00 Corporate Sponsorships Integrated Med Foundation $4,500.00 Corporate Sponsorships International Aids Society-- $50,000.00 Educational Grants Usa International Aids Society-- $75,000.00 Educational Grants Usa International Alliance for $5,000.00 Educational Grants Biological Standardization International Association $25,000.00 Corporate Sponsorships for The Study of Lung Cancer International Association $95,150.00 Corporate Sponsorships for The Study of Lung Cancer International Association $264,000.00 Corporate Sponsorships for The Study of Lung Cancer International Association $75,000.00 Corporate Sponsorships for The Study of Lung Cancer International Association $75,000.00 Corporate Sponsorships for The Study of Lung Cancer International Cancer $10,000.00 Corporate Sponsorships Advocacy Netwk International Chinese $10,000.00 Corporate Sponsorships Statistical Associate International Dermatology $70,000.00 Corporate Sponsorships Outcome Measures International Dermatology $150,000.00 Corporate Sponsorships Outcome Measures International League of $20,000.00 Charitable Donations Associate for Rheumlgy International Medical Corps $5,000.00 Charitable Donations International Pelvic Pain $21,000.00 Corporate Sponsorships Society International Physician $90,000.00 Corporate Sponsorships Ntwrk Dba International Oncology Ntwrk International Physician $50,000.00 Corporate Sponsorships Ntwrk Dba International Oncology Ntwrk International Physician $75,000.00 Corporate Sponsorships Ntwrk Dba International Oncology Ntwrk International Society for $5,000.00 Educational Grants Antiviral Research International Society for $3,000.00 Educational Grants The Study of Xenobiotics International Society of $86,420.00 Corporate Sponsorships Nephrology Iraq And Afghanistan $15,000.00 Corporate Sponsorships Veterans Jefferson Med College at $10,000.00 Educational Grants Thomas Jefferson Univ Jefferson Med College at $3,000.00 Corporate Sponsorships Thomas Jefferson Univ Jefferson Med College at $5,000.00 Educational Grants Thomas Jefferson Univ Jewish Hospital $7,500.00 Corporate Sponsorships Johns Hopkins Technology $40,000.00 Fellowships and Ventures Scholarships Johns Hopkins Technology $40,000.00 Fellowships and Ventures Scholarships Johns Hopkins Technology $40,000.00 Fellowships and Ventures Scholarships Johns Hopkins Technology $1,500.00 Corporate Sponsorships Ventures Johns Hopkins Technology $6,500.00 Fellowships and Ventures Scholarships Johns Hopkins Univ School $25,000.00 Corporate Sponsorships of Medicine Johns Hopkins Univ School $20,000.00 Educational Grants of Medicine Jonathan Wood and Associate $10,000.00 Corporate Sponsorships JWC Covenant Inc. $50,000.00 Educational Grants Kansas Univ Endowment $1,000.00 Charitable Donations Association Keystone Symposia $25,000.00 Corporate Sponsorships Keystone Symposia $25,000.00 Corporate Sponsorships Kidney Foundation Inc.. $5,000.00 Corporate Sponsorships Northeast Laboratorio Clinico Toledo $735.00 Patient Support Laboratorio Clinico Toledo $1,185.00 Patient Support Laboratorio Clinico Toledo $1,500.00 Patient Support Laboratorio Clinico Toledo $450.00 Patient Support Laboratorio Clinico Toledo $750.00 Patient Support Laboratorio Clinico Toledo $270.00 Patient Support Laboratorio Clinico Toledo $1,545.00 Patient Support Laboratorio Clinico Toledo $552.00 Patient Support Laboratorio Clinico Toledo $375.00 Patient Support Laboratorio Clinico Toledo $375.00 Patient Support Laboratorio Clinico Toledo $675.00 Patient Support Laboratorio Clinico Toledo $1,095.00 Patient Support Laboratorio Clinico Toledo $2,085.00 Patient Support Laboratorio Clinico Toledo $6,000.00 Patient Support Laboratorio Clinico Toledo $375.00 Patient Support Laboratorio Clinico Toledo $375.00 Patient Support Laboratorio Clinico Toledo $705.00 Patient Support Laboratorio Clinico Toledo $2,250.00 Patient Support Laboratorio Clinico Toledo $375.00 Patient Support Laboratorio Clinico Toledo $375.00 Patient Support Laboratorio Clinico Toledo $390.00 Patient Support Laboratorio Clinico Toledo $525.00 Patient Support Laboratorio Clinico Toledo $750.00 Patient Support Laboratorio Clinico Toledo $1,035.00 Patient Support Laboratorio Clinico Toledo $1,125.00 Patient Support Laboratorio Clinico Toledo $1,185.00 Patient Support Laboratorio Clinico Toledo $1,500.00 Patient Support Laboratorio Clinico Toledo $1,515.00 Patient Support Laboratorio Clinico Toledo $750.00 Patient Support Laboratorio Clinico Toledo $1,500.00 Patient Support Laboratorio Clinico Toledo $1,950.00 Patient Support Laboratorio Clinico Toledo $735.00 Patient Support Laboratorio Clinico Toledo $735.00 Patient Support Laboratorio Clinico Toledo $555.00 Patient Support Laboratorio Clinico Toledo $1,125.00 Patient Support Laboratorio Clinico Toledo $375.00 Patient Support Laboratorio Clinico Toledo $750.00 Patient Support Laboratorio Clinico Toledo $855.00 Patient Support Laboratorio Clinico Toledo $1,020.00 Patient Support Laboratorio Clinico Toledo $1,125.00 Patient Support Laboratorio Clinico Toledo $375.00 Patient Support Laboratorio Clinico Toledo $375.00 Patient Support Laboratorio Clinico Toledo $990.00 Patient Support Laboratorio Clinico Toledo $1,125.00 Patient Support Laboratorio Clinico Toledo $1,500.00 Patient Support Laboratorio Clinico Toledo $3,000.00 Patient Support Laboratorio Clinico Toledo $360.00 Patient Support Laboratorio Clinico Toledo $375.00 Patient Support Laboratorio Clinico Toledo $510.00 Patient Support Laboratorio Clinico Toledo $600.00 Patient Support Laboratorio Clinico Toledo $750.00 Patient Support Laboratorio Clinico Toledo $2,595.00 Patient Support Laboratorio Clinico Toledo $750.00 Patient Support Laboratorio Clinico Toledo $375.00 Patient Support Laboratorio Clinico Toledo $450.00 Patient Support Laboratorio Clinico Toledo $825.00 Patient Support Laboratorio Clinico Toledo $1,035.00 Patient Support Laboratorio Clinico Toledo $1,500.00 Patient Support Laboratorio Clinico Toledo $1,860.00 Patient Support Laboratorio Clinico Toledo $1,080.00 Patient Support Laboratorio Clinico Toledo $1,500.00 Patient Support Laboratorio Clinico Toledo $750.00 Patient Support Laboratorio Clinico Toledo $750.00 Patient Support Laboratorio Clinico Toledo $1,005.00 Patient Support Laboratorio Clinico Toledo $1,125.00 Patient Support Laboratorio Clinico Toledo $1,500.00 Patient Support Laboratorio Clinico Toledo $750.00 Patient Support Laboratorio Clinico Toledo $1,500.00 Patient Support Laboratorio Clinico Toledo $1,500.00 Patient Support Laboratorio Clinico Toledo $1,500.00 Patient Support Laboratorio Clinico Toledo $900.00 Patient Support Laboratorio Clinico Toledo $1,290.00 Patient Support Laboratorio Clinico Toledo $450.00 Patient Support Laboratorio Clinico Toledo $525.00 Patient Support Laboratorio Clinico Toledo $600.00 Patient Support Laboratorio Clinico Toledo $750.00 Patient Support Laboratorio Clinico Toledo $1,050.00 Patient Support Laboratorio Clinico Toledo $1,380.00 Patient Support Laboratorio Clinico Toledo $750.00 Patient Support Laboratorio Clinico Toledo $750.00 Patient Support Laboratorio Clinico Toledo $690.00 Patient Support Laboratorio Clinico Toledo $720.00 Patient Support Laboratorio Clinico Toledo $739.00 Patient Support Laboratorio Clinico Toledo $750.00 Patient Support Laboratorio Clinico Toledo $885.00 Patient Support Laboratorio Clinico Toledo $1,035.00 Patient Support Laboratorio Clinico Toledo $3,000.00 Patient Support Laboratorio Clinico Toledo $240.00 Patient Support Laboratorio Clinico Toledo $2,220.00 Patient Support Lake County Haven $10,000.00 Charitable Donations Large Urology Group $25,000.00 Corporate Sponsorships Practice Associate Large Urology Group $66,400.00 Corporate Sponsorships Practice Associate Large Urology Group $20,000.00 Corporate Sponsorships Practice Associate Latino Center On Aging $5,000.00 Corporate Sponsorships Lenox Hill Hospital $10,000.00 Educational Grants Leukemia and Lymphoma $1,267,000.00 Charitable Donations Society Leukemia and Lymphoma $50,000.00 Educational Grants Society Leukemia and Lymphoma $5,000.00 Corporate Sponsorships Society Leukemia and Lymphoma $25,000.00 Educational Grants Society Leukemia and Lymphoma $15,000.00 Corporate Sponsorships Society Leukemia and Lymphoma $50,000.00 Educational Grants Society Leukemia and Lymphoma $2,500.00 Corporate Sponsorships Society Leukemia and Lymphoma $75,000.00 Educational Grants Society Leukemia and Lymphoma $32,500.00 Corporate Sponsorships Society Leukemia and Lymphoma $50,000.00 Educational Grants Society Leukemia and Lymphoma $30,000.00 Corporate Sponsorships Society Leukemia and Lymphoma $100,000.00 Corporate Sponsorships Society Leukemia and Lymphoma $10,000.00 Corporate Sponsorships Society Leukemia Research $50,000.00 Fellowships and Foundation Scholarships Leukemia Research $5,000.00 Patient Support Foundation Leukemia Research $5,000.00 Educational Grants Foundation Leukemia Research $3,000.00 Corporate Sponsorships Foundation Liver Health Connection $75,000.00 Fellowships and Scholarships Liver Health Connection $5,000.00 Corporate Sponsorships Livestrong Foundation $10,000.00 Patient Support Lone Star Parkinson Society $500.00 Corporate Sponsorships Louisiana Urological $5,000.00 Corporate Sponsorships Society Loyola Stritch School of $1,000.00 Charitable Donations Medicine Division of Dermatology Loyola Stritch School of $1,000.00 Charitable Donations Medicine Division of Dermatology Lung Cancer Alliance $25,000.00 Corporate Sponsorships Lung Cancer Alliance $100,000.00 Corporate Sponsorships Lung Cancer Alliance $50,000.00 Corporate Sponsorships Lung Cancer Alliance $50,000.00 Corporate Sponsorships Lung Cancer Research $50,000.00 Charitable Donations Foundation Lung Cancer Research $25,000.00 Charitable Donations Foundation Lungevity Foundation $50,000.00 Educational Grants Lungevity Foundation $5,000.00 Corporate Sponsorships Lungevity Foundation $2,500.00 Corporate Sponsorships Lungevity Foundation $25,000.00 Corporate Sponsorships Lungevity Foundation $75,000.00 Corporate Sponsorships Lupus and Allied Diseases $6,000.00 Corporate Sponsorships Association Lupus and Allied Diseases $25,000.00 Corporate Sponsorships Association Lupus and Allied Diseases $35,000.00 Corporate Sponsorships Association Lupus Foundation New $5,000.00 Corporate Sponsorships England, Inc. Lupus Foundation of Florida $5,000.00 Corporate Sponsorships Inc. Lupus Research Alliance, $15,000.00 Corporate Sponsorships Inc. Lymphoma Research $5,000.00 Corporate Sponsorships Foundation Lymphoma Research $40,000.00 Corporate Sponsorships Foundation Lymphoma Research $10,000.00 Corporate Sponsorships Foundation Lymphoma Research $10,000.00 Corporate Sponsorships Foundation MS Cure Fund Inc. $15,000.00 Educational Grants Magellan Rx Management Inc. $20,000.00 Corporate Sponsorships March of Dimes Foundation $5,000.00 Charitable Donations Massachusetts Association $4,000.00 Corporate Sponsorships for Mental Health Massachusetts General $40,000.00 Fellowships and Hospital Scholarships Massachusetts General $10,000.00 Corporate Sponsorships Hospital for Children Massachusetts General $85,000.00 Corporate Sponsorships Hospital for Children Massachusetts Prostate $2,500.00 Educational Grants Cancer Coalition Massachusetts Society for $7,500.00 Educational Grants Med Research Massachusetts Society of $5,000.00 Corporate Sponsorships Clinical Oncologists ME Strong Inc. $2,500.00 Corporate Sponsorships Med--LQ LLC $50,000.00 Educational Grants Med College of Wisconsin $2,000.00 Corporate Sponsorships Med College of Wisconsin $1,000.00 Corporate Sponsorships Med Univ of South Carolina $5,000.00 Educational Grants Foundation Medical Learning Institute $33,790.00 Educational Grants Medical Learning Institute $75,000.00 Educational Grants Medical Learning Institute $42,300.00 Educational Grants Medical Learning Institute $116,850.00 Educational Grants Medical Univ of South $10,000.00 Educational Grants Carolina Medina Community Clinic $1,000.00 Corporate Sponsorships Medscape LLC $50,000.00 Educational Grants Medscape LLC $125,000.00 Educational Grants Medscape LLC $175,000.00 Educational Grants Medscape LLC $200,000.00 Educational Grants Medscape LLC $212,000.00 Educational Grants Medscape LLC $235,500.00 Educational Grants Medscape LLC $565,100.00 Educational Grants Medscape LLC $38,000.00 Educational Grants Medscape LLC $52,500.00 Educational Grants Medscape LLC $300,000.00 Educational Grants Medscape LLC $33,500.00 Educational Grants Memorial Sloan Kettering $25,000.00 Educational Grants Cancer Center Memphis Business Group On $5,100.00 Corporate Sponsorships Health Mens Health and Wellness $1,500.00 Corporate Sponsorships Center Mercy Med Center Inc. $3,250.00 Corporate Sponsorships Mercy Med Center Inc. $3,250.00 Corporate Sponsorships Methodist Hospital $25,000.00 Corporate Sponsorships Methodist Hospital $1,000.00 Corporate Sponsorships Michael J Fox Foundation $1,000.00 Corporate Sponsorships Michael J Fox Foundation $50,000.00 Corporate Sponsorships Michigan Institute of $5,000.00 Corporate Sponsorships Urology, PC Michigan Parkinson $10,000.00 Corporate Sponsorships Foundation Michigan Parkinson $1,000.00 Corporate Sponsorships Foundation Michigan Rheumatism Society $25,000.00 Corporate Sponsorships Mid America MS Achievement $2,000.00 Corporate Sponsorships Center Midwest Business Group on $2,500.00 Corporate Sponsorships Health Midwest Business Group on $2,500.00 Corporate Sponsorships Health Miles for Cystic Fibrosis $2,500.00 Corporate Sponsorships Minnesota Urological $5,000.00 Corporate Sponsorships Society Missouri Hepatitis C $20,000.00 Educational Grants Alliance Mount Sinai School of $10,000.00 Educational Grants Medicine Mount Sinai School of $40,000.00 Fellowships and Medicine Scholarships Mount Sinai School of $30,000.00 Corporate Sponsorships Medicine Mount Sinai School of $40,000.00 Educational Grants Medicine Movement Disorder Society $1,000.00 Corporate Sponsorships Movement Disorder Society $20,000.00 Educational Grants Movement Disorder Society $321,500.00 Corporate Sponsorships Movement Disorder Society $12,000.00 Educational Grants Movement Disorder Society $11,000.00 Corporate Sponsorships MS Views and News Inc. $5,000.00 Educational Grants Multiple Myeloma Research $10,000.00 Educational Grants Foundation Inc. Multiple Myeloma Research $25,000.00 Educational Grants Foundation Inc. Multiple Myeloma Research $15,000.00 Educational Grants Foundation Inc. Multiple Myeloma Research $50,000.00 Fellowships and Foundation Inc. Scholarships Multiple Sclerosis $5,000.00 Patient Support Foundation Inc. Musella Foundation for $25,000.00 Charitable Donations Brain Tumor Research and Information Inc. Nashville Cares Inc. $8,000.00 Corporate Sponsorships National Academy of $30,000.00 Corporate Sponsorships Dermatology Nurse Practitioners National Aids Treatment $300,000.00 Patient Support Advocacy Project National Alliance of Mental $5,000.00 Corporate Sponsorships Illness Flordia National Alliance of Mental $7,500.00 Corporate Sponsorships Illness Tennessee National Alliance of State $10,000.00 Corporate Sponsorships and Territorial AIDS Directors National Alliance of State $50,000.00 Charitable Donations and Territorial Aids Directors National Animal Interest $20,000.00 Charitable Donations Alliance National Associate of $45,000.00 Educational Grants Managed Care Physician National Associate of $10,500.00 Corporate Sponsorships Managed Care Physician National Associate of $20,000.00 Educational Grants Managed Care Physician National Associate of $25,000.00 Educational Grants Managed Care Physician National Associate of $45,000.00 Educational Grants Managed Care Physician National Associate of $20,000.00 Educational Grants Managed Care Physician National Associate of $35,000.00 Educational Grants Managed Care Physician National Associate of $10,500.00 Corporate Sponsorships Managed Care Physician National Associate of $10,000.00 Charitable Donations Pediatric Nurse Practitioners National Association of $2,500.00 Corporate Sponsorships Hispanic Nurses National Association of $25,000.00 Corporate Sponsorships Latino Elected and Appointed officials Education Fund National Brain Tumor $50,000.00 Patient Support Society (Nbts) National Brain Tumor $25,000.00 Corporate Sponsorships Society, Inc. National Breast Cancer $5,000.00 Patient Support Coalition Fund National Business Coalition $7,500.00 Corporate Sponsorships On Health National Business Group On $25,000.00 Corporate Sponsorships Health National Coalition for $40,000.00 Corporate Sponsorships Cancer National Coalition for $2,500.00 Corporate Sponsorships Cancer National Commission On $10,000.00 Educational Grants Correctional Health Care National Committee of $125,000.00 Corporate Sponsorships Quality Assurance National Community $25,000.00 Corporate Sponsorships Dispensing Associate NCODA National Community $30,000.00 Corporate Sponsorships Dispensing Associate NCODA National Community $35,000.00 Corporate Sponsorships Dispensing Associate NCODA National Comprehensive $90,898.00 Educational Grants Cancer Network National Comprehensive $25,000.00 Educational Grants Cancer Network National Comprehensive $10,000.00 Educational Grants Cancer Network National Comprehensive $25,000.00 Educational Grants Cancer Network National Comprehensive $50,000.00 Educational Grants Cancer Network National Comprehensive $25,000.00 Educational Grants Cancer Network National Comprehensive $50,000.00 Educational Grants Cancer Network National Comprehensive $75,000.00 Educational Grants Cancer Network National Comprehensive $55,000.00 Educational Grants Cancer Network National Comprehensive $50,000.00 Charitable Donations Cancer Network National Comprehensive $15,000.00 Educational Grants Cancer Network National Comprehensive $75,000.00 Educational Grants Cancer Network National Federation of $5,000.00 Corporate Sponsorships Independent National Foundation for The ($81,525.67) Educational Grants Centers for Disease Control and Prevention National Hispanic Council $25,000.00 Corporate Sponsorships On Aging National Kdny Foundation $292,054.00 Educational Grants Inc. National Medical $7,500.00 Educational Grants Association National Minority Quality $25,000.00 Corporate Sponsorships forum National Multiple Sclerosis $10,000.00 Corporate Sponsorships Society National Multiple Sclerosis $2,500.00 Corporate Sponsorships Society National Multiple Sclerosis $2,000.00 Corporate Sponsorships Society National Multiple Sclerosis $25,000.00 Corporate Sponsorships Society-Greater Illinois Chapter National Organization of $5,000.00 Corporate Sponsorships Rheumatology Managers National Pancreas $80,000.00 Charitable Donations Foundation National Pancreas $80,000.00 Charitable Donations Foundation National Pancreas $85,000.00 Educational Grants Foundation National Pancreas $190,000.00 Educational Grants Foundation National Pancreas $3,500.00 Corporate Sponsorships Foundation National Pancreas $1,000.00 Corporate Sponsorships Foundation National Pancreas $85,000.00 Charitable Donations Foundation National Pancreas $85,000.00 Educational Grants Foundation National Parkinson $2,500.00 Corporate Sponsorships Foundation Inc. National Parkinson $1,250.00 Corporate Sponsorships Foundation Inc. National Parkinson $85,000.00 Corporate Sponsorships Foundation Inc. National Parkinson $45,000.00 Educational Grants Foundation Inc. National Parkinson $50,000.00 Educational Grants Foundation Inc. National Parkinson $5,000.00 Corporate Sponsorships Foundation Inc. National Psoriasis $50,000.00 Corporate Sponsorships Foundation National Psoriasis $25,000.00 Corporate Sponsorships Foundation National Psoriasis $35,000.00 Corporate Sponsorships Foundation National Psoriasis $50,000.00 Corporate Sponsorships Foundation National Psoriasis $35,000.00 Corporate Sponsorships Foundation National Psoriasis $15,000.00 Corporate Sponsorships Foundation National Psoriasis $10,000.00 Educational Grants Foundation National Psoriasis $75,000.00 Corporate Sponsorships Foundation National Psoriasis $25,000.00 Educational Grants Foundation National Psoriasis $15,000.00 Corporate Sponsorships Foundation National Psoriasis $10,000.00 Educational Grants Foundation National Psoriasis $15,000.00 Educational Grants Foundation National Psoriasis $50,000.00 Educational Grants Foundation National Psoriasis $35,000.00 Educational Grants Foundation National Psoriasis $5,000.00 Corporate Sponsorships Foundation National Psoriasis $50,000.00 Educational Grants Foundation National Psoriasis $25,000.00 Corporate Sponsorships Foundation National Psoriasis $100,000.00 Corporate Sponsorships Foundation National Psoriasis $150,000.00 Corporate Sponsorships Foundation National Psoriasis $20,000.00 Corporate Sponsorships Foundation National Psoriasis $30,000.00 Corporate Sponsorships Foundation National Psoriasis $30,000.00 Corporate Sponsorships Foundation National Psoriasis $30,000.00 Corporate Sponsorships Foundation National Psoriasis $35,000.00 Corporate Sponsorships Foundation National Psoriasis $40,000.00 Corporate Sponsorships Foundation National Society for $50,000.00 Corporate Sponsorships Cutaneous Medicine National Society for $140,000.00 Corporate Sponsorships Cutaneous Medicine National Society for $150,000.00 Corporate Sponsorships Cutaneous Medicine Neuro Challenge Foundation $25,000.00 Corporate Sponsorships Inc. Neurologic Disease $4,995.00 Educational Grants Foundation New England Dermatological $75,000.00 Corporate Sponsorships Society New England Immunology $2,000.00 Corporate Sponsorships Conference Inc. New England Quality Care $5,000.00 Corporate Sponsorships Alliance New Venture Fund $10,000.00 Educational Grants New York Academy of Science $2,500.00 Educational Grants New York Academy of Science $5,000.00 Corporate Sponsorships New York Med Colllege $50,000.00 Educational Grants office of Continuing Med Education New York Society for $55,000.00 Corporate Sponsorships Gastrointestinal Endoscopy New York State Rheumlgy $18,000.00 Corporate Sponsorships Society New York State Rheumlgy $22,500.00 Corporate Sponsorships Society Nexus Global Group Science $5,000.00 Corporate Sponsorships Nicole T. Jarvis, M.D., $2,500.00 Corporate Sponsorships PLLC NL Communications Inc. $50,000.00 Educational Grants NL Communications Inc. $35,000.00 Educational Grants NL Communications Inc. $35,000.00 Educational Grants NL Communications Inc. $35,000.00 Educational Grants NL Communications Inc. $40,000.00 Educational Grants NL Communications Inc. $20,000.00 Educational Grants NL Communications Inc. $40,000.00 Educational Grants NL Communications Inc. $20,000.00 Educational Grants NL Communications Inc. $65,000.00 Educational Grants NL Communications Inc. $75,000.00 Educational Grants NL Communications Inc. $50,000.00 Educational Grants NL Communications Inc. $30,000.00 Educational Grants NL Communications Inc. $75,000.00 Educational Grants North American Center for $375,025.00 Educational Grants Continuing Med Education North American Center for $90,000.00 Educational Grants Continuing Med Education North American Society for $15,000.00 Educational Grants Pediatric Gastroenterology Hepatology and Nutrition North Carolina Biosciences $2,000.00 Corporate Sponsorships Organization North Dakota Pharmacists $2,500.00 Corporate Sponsorships Association Northeast Business Group On $15,000.00 Corporate Sponsorships Health Northeast Business Group On $15,000.00 Corporate Sponsorships Health Northeastern University $1,000.00 Charitable Donations Northern Illinois $1,000.00 Charitable Donations University Foundation Northwest Health Law $1,000.00 Corporate Sponsorships Advocates Northwest Indiana $1,000.00 Corporate Sponsorships Parkinsons Northwest Kidney Centers $2,500.00 Corporate Sponsorships Northwest Parkinsons $5,000.00 Educational Grants Foundation Northwest Parkinsons $14,900.00 Corporate Sponsorships Foundation Northwestern Univ $25,000.00 Corporate Sponsorships Northwestern Univ $50,000.00 Fellowships and Scholarships Norton Healthcare $3,000.00 Corporate Sponsorships Foundation Norwich University $1,000.00 Charitable Donations NYU School of Medicine $5,000.00 Educational Grants NYU School of Medicine $10,000.00 Educational Grants NYU School of Medicine $7,500.00 Educational Grants NYU School of Medicine $10,000.00 Educational Grants NYU School of Medicine $20,000.00 Educational Grants Ocular Immunology and $5,000.00 Corporate Sponsorships Uveitis Foundation Ocular Immunology and $15,000.00 Corporate Sponsorships Uveitis Foundation Ohio Association of $10,000.00 Corporate Sponsorships Rheumatology Ohio Gastroenterology $1,250.00 Corporate Sponsorships Society Ohio Gastroenterology $1,250.00 Corporate Sponsorships Society Ohio Gastroenterology $2,500.00 Corporate Sponsorships Society Omnia Education Inc. $98,000.00 Educational Grants Omnia Education Inc. $350,000.00 Educational Grants Oncology Nursing Society $20,200.00 Corporate Sponsorships Oradian Inc. $75,000.00 Corporate Sponsorships Oregon Health and Science $3,500.00 Corporate Sponsorships Univ Oregon Health and Science $20,000.00 Educational Grants Univ Oregon Health and Science $5,000.00 Educational Grants Univ Oregon Health and Science $3,000.00 Educational Grants Univ Oregon Health and Science $20,000.00 Educational Grants Univ Osmania Gandhi Kakatiya $2,500.00 Corporate Sponsorships Medical Alumni Association of America Pacific Dermatologic $20,000.00 Corporate Sponsorships Association Pacific Dermatologic $20,000.00 Corporate Sponsorships Association Pack Center LLC $22,575.00 Educational Grants Pack Center LLC $175,000.00 Educational Grants Pack Health LLC $119,750.00 Educational Grants Pack Health LLC $80,000.00 Educational Grants Pack Health LLC $79,750.00 Educational Grants Pack Health LLC $50,000.00 Educational Grants Pack Health LLC $42,875.00 Educational Grants Pack Health LLC $42,875.00 Educational Grants Pack Center LLC $100,000.00 Educational Grants Pancreas Club $10,000.00 Educational Grants Pancreatic Cancer Action $50,000.00 Educational Grants Network Pancreatic Cancer Action $282,000.00 Corporate Sponsorships Network Park Nicollet Foundation $1,000.00 Corporate Sponsorships Parkinson and Movement $20,000.00 Educational Grants Disorder Alliance Parkinson and Movement $4,000.00 Corporate Sponsorships Disorder Alliance Parkinson and Movement $2,500.00 Corporate Sponsorships Disorder Alliance Parkinson Association $1,000.00 Corporate Sponsorships Parkinson Association $5,000.00 Corporate Sponsorships Parkinson Council $25,000.00 Corporate Sponsorships Parkinson Foundation $2,500.00 Corporate Sponsorships Parkinson Foundation $5,000.00 Corporate Sponsorships Parkinson Foundation $10,000.00 Educational Grants Parkinson Foundation $2,500.00 Corporate Sponsorships Parkinson Study Group $20,000.00 Educational Grants Parkinson Study Group $15,000.00 Corporate Sponsorships Parkinson Study Group $2,716.00 Fellowships and Scholarships Parkinson Support Center of $5,000.00 Corporate Sponsorships Kentuciana Parkinson Support Center of $5,000.00 Corporate Sponsorships Kentuciana Parkinsons and Movement $1,500.00 Corporate Sponsorships Disorder Foundation Parkinsons Association $1,000.00 Corporate Sponsorships Parkinsons Association $8,000.00 Educational Grants Parkinsons Association $8,000.00 Educational Grants Parkinson's Awareness $1,500.00 Corporate Sponsorships Association of Central Indiana Parkinsons Disease $5,000.00 Corporate Sponsorships Foundation Parkinsons Disease $10,000.00 Corporate Sponsorships Foundation Parkinsons Institute $5,000.00 Corporate Sponsorships Parkinson's Nebraska $1,000.00 Corporate Sponsorships Parkinsons Outreach $1,000.00 Corporate Sponsorships Association Partnership for Quality Med $2,000.00 Charitable Donations Donations Pqmd Patient Access Network $287,000.00 Charitable Donations Foundation Patient Access Network $2,284,000.00 Charitable Donations Foundation Patient Access Network $10,000,000.00 Charitable Donations Foundation Patient Access Network $7,577,000.00 Charitable Donations Foundation Patient Access Network $15,000,000.00 Charitable Donations Foundation Patient Empowerment Ntwrk $40,000.00 Educational Grants Patient Empowerment Ntwrk $25,000.00 Educational Grants Patient Empowerment Ntwrk $30,000.00 Educational Grants Patient Empowerment Ntwrk $30,000.00 Educational Grants Patient Empowerment Ntwrk $30,000.00 Educational Grants Patient Empowerment Ntwrk $20,000.00 Educational Grants Patient Empowerment Ntwrk $15,000.00 Educational Grants Patient Empowerment Ntwrk $20,000.00 Educational Grants Patient Empowerment Ntwrk $35,000.00 Educational Grants Pcec Prostrate Conditions $2,500.00 Corporate Sponsorships Education Council Pediatric Endocrine Society $3,750.00 Corporate Sponsorships Pediatric Endocrine Society $50,000.00 Corporate Sponsorships Pediatric Endocrinology $2,500.00 Corporate Sponsorships Nursing Society Pediatric Endocrinology $17,000.00 Corporate Sponsorships Nursing Society Pediatric Ibd Foundation $10,000.00 Corporate Sponsorships Peerview Institute for ($2,000.00) Educational Grants Medical Education Pennsylvania Academy of $10,000.00 Corporate Sponsorships Dermatology and Dermatologic Surgry Pennsylvania Biotechnology $3,000.00 Corporate Sponsorships Association Pennsylvania Prostate $5,000.00 Educational Grants Cancer Coalition Pennsylvania Society of $5,000.00 Corporate Sponsorships Gastroenterology People To People Health $20,000.00 Charitable Donations Foundation People To People Health $20,000.00 Charitable Donations Foundation Performrx $5,000.00 Corporate Sponsorships Pharmaceutical Research and $20,000.00 Corporate Sponsorships Manufacturers of America Philadelphia Research and $5,500.00 Educational Grants Education Foundation Phrmct Care Management $73,000.00 Corporate Sponsorships Associate Phrmct Care Management $88,000.00 Corporate Sponsorships Associate Phrmct Care Management $73,000.00 Corporate Sponsorships Associate Physicians Education $25,000.00 Educational Grants Resource LLC Physicians Education $75,000.00 Educational Grants Resource LLC Physicians Education $50,000.00 Educational Grants Resource LLC Physicians Education $50,000.00 Educational Grants Resource LLC Pink Door Nonprofit $2,400.00 Corporate Sponsorships Organization Pins for Parkinsons $500.00 Corporate Sponsorships Pittsburgh Business Group $13,000.00 Corporate Sponsorships On Health Pittsburgh Business Group $13,000.00 Corporate Sponsorships On Health Postgraduate Institute for $59,725.00 Educational Grants Medicine Presbyterian Healthcare $5,000.00 Corporate Sponsorships Foundation President and Fellows of $1,500.00 Educational Grants Harvard College Prevent Cancer Foundation $25,000.00 Charitable Donations Prevent Cancer Foundation $100,000.00 Corporate Sponsorships Prevent Cancer Foundation $5,000.00 Corporate Sponsorships Prime Education Inc. $150,000.00 Educational Grants Prime Education Inc. $225,000.00 Educational Grants Prime Education Inc. $190,000.00 Educational Grants Prime Education Inc. $244,000.00 Educational Grants Prime Education Inc. $332,620.00 Educational Grants Prime Education Inc. $100,000.00 Educational Grants Prime Education Inc. $200,000.00 Educational Grants Prime Education Inc. $100,000.00 Educational Grants Prime Education Inc. $106,400.00 Educational Grants Prime Education Inc. $128,902.00 Educational Grants Prime Oncology Inc. $25,000.00 Educational Grants Prime Oncology Inc. $155,125.00 Educational Grants Prime Oncology Inc. $75,000.00 Educational Grants Prime Oncology Inc. $154,150.00 Educational Grants Primo Education LLC $50,000.00 Educational Grants Princeton Univ Trustees $50,000.00 Educational Grants Project Inform $75,000.00 Charitable Donations Project Inform, Inc. $30,000.00 Corporate Sponsorships Project Spark Foundation $1,500.00 Corporate Sponsorships Projects in Knowledge Inc. $125,000.00 Educational Grants Projects in Knowledge Inc. $80,000.00 Educational Grants Projects in Knowledge Inc. $150,000.00 Educational Grants Prostate Cancer Foundation $4,000.00 Corporate Sponsorships Chicago Prostate Cancer $5,000.00 Patient Support International Prostate Cancer Research $15,000.00 Corporate Sponsorships Instutute Prostate Health Education $7,500.00 Educational Grants Network Prostate Health Education $5,000.00 Educational Grants Network Prostaware $1,500.00 Corporate Sponsorships Psoriasis and Psoriatic $100,000.00 Corporate Sponsorships Arthritis Clinics Multicenter Advancement Network Psoriasis and Psoriatic $100,000.00 Corporate Sponsorships Arthritis Clinics Multicenter Advancement Network Puerto Rico Associate of $20,000.00 Educational Grants Gastroenterology Puerto Rico Associate of $40,000.00 Corporate Sponsorships Gastroenterology Puerto Rico Associate of $10,000.00 Educational Grants Gastroenterology Purdue Univ College of $50,000.00 Educational Grants Pharmacy Purdue Univ College of $175,000.00 Educational Grants Pharmacy Recovery Idaho $1,000.00 Corporate Sponsorships Regents of The Univ of $40,000.00 Fellowships and California Scholarships Regents of The Univ of $55,000.00 Fellowships and California Scholarships Regents of The Univ of ($658.85) Educational Grants California Regents of The Univ of $5,000.00 Educational Grants California Regents of The Univ of $10,000.00 Educational Grants California Regents of The Univ of $5,000.00 Educational Grants California Regents of The Univ of $20,000.00 Educational Grants California Regents of The Univ of $5,000.00 Educational Grants Michigan Regents of The Univ of $20,000.00 Corporate Sponsorships Michigan Regents of the University $5,000.00 Educational Grants of Minnesota Rehabilitation and $2,500.00 Corporate Sponsorships Community Renal Physician Associate $30,000.00 Corporate Sponsorships Research Institute at $7,500.00 Corporate Sponsorships Nationwide Childrens Hospital Research Institute for Fox $5,000.00 Corporate Sponsorships Chase Cancer Center Rheumatology Association of $7,500.00 Corporate Sponsorships Iowa Rheumatology Association of $5,000.00 Corporate Sponsorships Iowa Rheumatology Association of $7,500.00 Corporate Sponsorships Iowa Rheumatology Association of $10,000.00 Corporate Sponsorships Minnesota and The Dakotas Rheumatology Nurses Society $75,000.00 Educational Grants Rheumatology Nurses Society $20,000.00 Educational Grants Rheumatology Nurses Society $46,325.00 Corporate Sponsorships Rheumatology Nurses Society $75,000.00 Educational Grants Rheumatology Nurses Society $75,000.00 Educational Grants Rheumatology Nurses Society $21,250.00 Corporate Sponsorships Rheumatology Nurses Society $45,000.00 Corporate Sponsorships Rheumlgy Alliance of $25,000.00 Corporate Sponsorships Louisiana Riverside Family Medicine $2,500.00 Educational Grants Residency The Riverside Medical Clinic $10,000.00 Educational Grants Charitable Foundation Robert Michael Educational $150,000.00 Educational Grants Institute LLC Rock Steady Boxing $500.00 Corporate Sponsorships Rocky Mountain MS Center $5,000.00 Educational Grants Rocky Mountain MS Center $10,000.00 Educational Grants Rocky Mountain MS Center $5,000.00 Educational Grants Rocky Mountain MS Center $5,000.00 Educational Grants Rocky Mountain MS Center $10,000.00 Educational Grants Roger Williams Medical $40,000.00 Fellowships and Center Scholarships Roger Williams Medical $5,000.00 Educational Grants Center Rotary Club of Downtown $1,000.00 Corporate Sponsorships Macon Rush Univ Medical Center $5,000.00 Educational Grants Rush Univ Medical Center $7,500.00 Educational Grants Rush Univ Medical Center $75,000.00 Educational Grants Rush Univ Medical Center $5,000.00 Charitable Donations Rush Univ Medical Center $75,000.00 Educational Grants Rush Univ Medical Center $75,000.00 Educational Grants Rutgers Univ Foundation $1,000.00 Charitable Donations Sacramento Gastrointestinal $1,500.00 Corporate Sponsorships Education and Research Safety Pharmacology Society $5,000.00 Educational Grants San Francisco Aids $10,000.00 Charitable Donations Foundation San Francisco Public Center $75,000.00 Charitable Donations Foundation San Francisco Retina $5,000.00 Educational Grants Foundation San Francisco Retina $5,000.00 Educational Grants Foundation San Juan Bautista Medical $40,000.00 Fellowships and Center Scholarships Scott and White Healthcare $1,000.00 Corporate Sponsorships Foundation Scripps Health $5,000.00 Educational Grants Scripps Health $5,000.00 Educational Grants Scripps Health $50,000.00 Educational Grants Scripps Research Institute $2,000.00 Educational Grants Seattle Science Foundation $2,500.00 Educational Grants Seattle Science Foundation $8,500.00 Educational Grants Seton Family of Hospitals $40,000.00 Fellowships and Scholarships Sexual Medicine Society of $5,000.00 Corporate Sponsorships North America Foundation(Smsna) Sexual Medicine Society of $225,000.00 Corporate Sponsorships North America Foundation(Smsna) Shanti Project Inc. $10,000.00 Patient Support Share $5,000.00 Educational Grants Share $10,000.00 Charitable Donations Sharsheret $10,000.00 Educational Grants Sheknows LLC $102,500.00 Corporate Sponsorships Sheknows LLC $57,500.00 Corporate Sponsorships Sheknows LLC $200,000.00 Corporate Sponsorships Sinai Health System $10,000.00 Charitable Donations Sociedad Dermatologica de $35,000.00 Patient Support Puerto Rico Sociedad PR Endocrinologia $15,000.00 Corporate Sponsorships y Diabetologia Sociedad Puertorriquena $2,000.00 Corporate Sponsorships Pediatria Sociedad Puertorriquena $9,500.00 Corporate Sponsorships Pediatria Sociedad Puertorriquena $14,000.00 Corporate Sponsorships Pediatria Society for Clinical $15,000.00 Corporate Sponsorships Research Sites Inc. Society for Clinical Trials $2,000.00 Corporate Sponsorships Society for Leukocyte $2,500.00 Educational Grants Biology Society for Mucosal $2,500.00 Educational Grants Immunology Society for Neuro-Oncology $50,000.00 Educational Grants Society for Neuro-Oncology $55,000.00 Corporate Sponsorships Society for Neuroscience $2,000.00 Educational Grants Society for Neuroscience $5,000.00 Educational Grants Society for Womens Health $15,000.00 Corporate Sponsorships Research Society for Womens Health $150,000.00 Corporate Sponsorships Research Society of Dermatology $40,000.00 Corporate Sponsorships Physician Assistants Society of Dermatology $45,000.00 Corporate Sponsorships Physician Assistants Society of Dermatology $40,000.00 Corporate Sponsorships Physician Assistants Society of Dermatology $40,000.00 Corporate Sponsorships Physician Assistants Society of Investigative $30,000.00 Educational Grants Dermatology Society of Nuclear Medicine $5,000.00 Corporate Sponsorships and Molecular Imaging Socty for Gynecologic $10,000.00 Corporate Sponsorships Investigation Socty for Immunotherapy of $50,000.00 Corporate Sponsorships Cancer South Carolina Alliance of $6,000.00 Corporate Sponsorships Health Plans South Dakota Parkinson $1,500.00 Corporate Sponsorships Foundation South Texas Association of $30,000.00 Corporate Sponsorships Rheumatologists South Texas Association of $40,000.00 Corporate Sponsorships Rheumatologists Spondylitis Association of $40,000.00 Educational Grants America Spondylitis Association of $20,000.00 Educational Grants America Spondyloarthritis Research $70,000.00 Corporate Sponsorships and Treatment Network Spartan Stage One Family Theatre $5,000.00 Corporate Sponsorships State of Maryland $40,000.00 Educational Grants State of Pennsylvania $25,065.00 Educational Grants State of Pennsylvania $90,000.00 Educational Grants State of Pennsylvania $25,000.00 Educational Grants State of Pennsylvania $25,000.00 Educational Grants Summit for Stem Cellular $2,500.00 Corporate Sponsorships Foundation Surviveit $10,000.00 Educational Grants Susan G Komen Breast Cancer $10,000.00 Charitable Donations Foundation Inc. Swedish Medical Center $5,000.00 Educational Grants First Hill Campus Take A Breather Foundation $5,000.00 Corporate Sponsorships Take A Breather Foundation $20,000.00 Corporate Sponsorships Talem Health Inc. $150,000.00 Educational Grants Tarsus Cardiology Inc. Dba $35,000.00 Corporate Sponsorships South Beach Symposium Tennessee Disability $7,500.00 Corporate Sponsorships Coalition Texas Academy of Family $2,500.00 Corporate Sponsorships Physicians Texas Neuro Society $5,000.00 Corporate Sponsorships Texas Society for $2,000.00 Corporate Sponsorships Gastroenterology and Endoscopy Texas Society for $2,000.00 Corporate Sponsorships Gastroenterology and Endoscopy Texas Society for $2,000.00 Corporate Sponsorships Gastroenterology and Endoscopy Texas Urological Society $6,000.00 Corporate Sponsorships Texas Urological Society $6,000.00 Corporate Sponsorships Thomas Jefferson University ($4,242.75) Educational Grants Thomas Jefferson University $5,000.00 Corporate Sponsorships Transcelerate Biopharma $1,500,000.00 Corporate Sponsorships Inc. Trustees of Boston Univ D/B/ $200,000.00 Educational Grants A Trustees of Boston Univ D/B/ $1,500.00 Educational Grants A Trustees of Boston Univ D/B/ $10,000.00 Educational Grants A Trustees of Dartmouth $1,000.00 Charitable Donations College--Administration Trustees of Tufts College $1,000.00 Charitable Donations Trustees of Tufts College $1,000.00 Charitable Donations Tufts Medical Center $50,000.00 Fellowships and Scholarships Tufts Medical Center $10,000.00 Educational Grants UC Regents Maxillofacial $10,000.00 Educational Grants Prosthetics Clinic UC Regents Maxillofacial $40,000.00 Fellowships and Prosthetics Clinic Scholarships UC Regents Maxillofacial $5,000.00 Educational Grants Prosthetics Clinic UC Regents Maxillofacial $15,000.00 Educational Grants Prosthetics Clinic UCSF Medical Center at $50,000.00 Educational Grants Parnassus Ultimate Medical Academy $225,000.00 Educational Grants LLC Ultimate Medical Academy $175,000.00 Educational Grants LLC Ultimate Medical Academy $225,000.00 Educational Grants LLC Ultimate Medical Academy $200,000.00 Educational Grants LLC Ultimate Medical Academy $213,500.00 Educational Grants LLC Ultimate Medical Academy $249,250.00 Educational Grants LLC Ultimate Medical Academy ($5,370.00) Educational Grants LLC Ultimate Medical Academy $250,000.00 Educational Grants LLC Ultimate Medical Academy $149,000.00 Educational Grants LLC Ultimate Medical Academy $250,000.00 Educational Grants LLC Ultimate Medical Academy $213,500.00 Educational Grants LLC Ultimate Medical Academy $115,000.00 Educational Grants LLC Ultimate Medical Academy $289,810.00 Educational Grants LLC UMA Education Inc. Dba $375,000.00 Educational Grants Global Education Group UMA Education Inc. Dba $200,000.00 Educational Grants Global Education Group UMA Education Inc. Dba $38,800.00 Educational Grants Global Education Group UMA Education Inc. Dba $80,000.00 Educational Grants Global Education Group UMASS Memorial Foundation $2,500.00 Corporate Sponsorships Inc. United Rheumatology $36,000.00 Corporate Sponsorships United Rheumatology $205,000.00 Corporate Sponsorships United States Adult Cystic $5,000.00 Educational Grants Fibrosis Association Inc. Univ Health Service at $1,166.00 Corporate Sponsorships Stony Point Inc. Univ Health Service at $1,167.00 Corporate Sponsorships Stony Point Inc. Univ Health Service at $1,167.00 Corporate Sponsorships Stony Point Inc. Univ Health Service at $5,000.00 Educational Grants Stony Point Inc. Univ Health Service at $20,000.00 Educational Grants Stony Point Inc. Univ Hospital of Brooklyn ($5,527.00) Educational Grants Univ of California $30,000.00 Corporate Sponsorships Berkeley--Administration Univ of California, $55,000.00 Fellowships and Riverside Student Health Scholarships Services Univ of Chicago $10,000.00 Educational Grants Univ of Chicago $5,000.00 Educational Grants Univ of Chicago $5,000.00 Educational Grants Univ of Chicago $65,000.00 Educational Grants Univ of Chicago $80,000.00 Educational Grants Univ of Chicago $140,000.00 Educational Grants Univ of Chicago $20,000.00 Corporate Sponsorships Univ of Chicago $15,000.00 Charitable Donations Univ of Chicago $10,000.00 Educational Grants Univ of Chicago $30,000.00 Educational Grants Univ of Cincinnati $60,000.00 Educational Grants Univ of Cincinnati $75,000.00 Educational Grants Univ of Cincinnati $195,000.00 Educational Grants Univ of Cincinnati $80,000.00 Educational Grants Univ of Cincinnati $250,000.00 Educational Grants Univ of Cincinnati $454,420.00 Educational Grants Univ of Cincinnati $25,000.00 Educational Grants Univ of Cincinnati ($1,212.00) Educational Grants Univ of Cincinnati $60,000.00 Educational Grants Univ of Cincinnati $75,000.00 Educational Grants Univ of Cincinnati $5,000.00 Educational Grants Foundation--Sunflower Fund Univ of Colorado Denver $25,000.00 Fellowships and School of Medicine Scholarships Univ of Colorado Denver $4,000.00 Educational Grants School of Medicine Univ of Florida Foundation $5,000.00 Educational Grants Univ of Florida Foundation $500.00 Corporate Sponsorships Univ of Florida Foundation $55,000.00 Fellowships and Scholarships Univ of Illinios $2,000.00 Educational Grants Univ of Illinois $1,000.00 Corporate Sponsorships Univ of Illinois Foundation $5,000.00 Corporate Sponsorships Univ of Illinois Foundation $5,000.00 Corporate Sponsorships Univ of Illinois Foundation $1,000.00 Charitable Donations Univ of Louisville Research $60,000.00 Educational Grants Foundation Univ of Louisville Research $98,000.00 Educational Grants Foundation Univ of Louisville Research $47,725.00 Educational Grants Foundation Univ of Louisville Research $1,000.00 Educational Grants Foundation Univ of Maryland Baltimore $10,000.00 Educational Grants Foundation Inc. Univ of Maryland Baltimore $10,000.00 Corporate Sponsorships Foundation Inc. Univ of Miami $50,000.00 Fellowships and Scholarships Univ of Miami $10,000.00 Educational Grants Univ of Miami Dept of $10,000.00 Corporate Sponsorships Dermatology Univ of Nebraska Med Center $150,000.00 Educational Grants Univ of Nebraska Med Center $675.00 Corporate Sponsorships Univ of Nebraska Med Center $68,900.00 Educational Grants Univ of Nebraska Med Center $25,000.00 Educational Grants Univ of Nebraska Med Center $25,000.00 Educational Grants Univ of Nebraska Med Center $5,000.00 Educational Grants Univ of Nebraska Med Center $7,500.00 Educational Grants Univ of Nebraska Med Center $5,000.00 Corporate Sponsorships Univ of New Mexico $5,000.00 Corporate Sponsorships Foundation Univ of North Carolina at $40,000.00 Fellowships and Chapel Hill Scholarships Univ of North Carolina at ($5,463.46) Educational Grants Chapel Hill Univ of North Carolina at ($40,000.00) Fellowships and Chapel Hill Scholarships Univ of Pittsburgh $2,200.00 Educational Grants Univ of Pittsburgh $10,000.00 Educational Grants Univ of Pittsburgh $15,000.00 Educational Grants Univ of Pittsburgh $2,500.00 Corporate Sponsorships Univ of Pittsburgh $15,000.00 Educational Grants Univ of Rhode Island $2,500.00 Educational Grants Foundation Univ of South Alabama $1,500.00 Corporate Sponsorships College of Medicine Univ of South Florida $25,000.00 Educational Grants Health Professions Conferencing Corp Univ of Southern California $25,000.00 Educational Grants Univ of Southern California $50,000.00 Fellowships and Scholarships Univ of Southern California $78,500.00 Fellowships and Scholarships Univ of Tennessee Obgyn ($1,758.03) Educational Grants Center Univ of Tennessee Obgyn $2,000.00 Corporate Sponsorships Center Univ of Texas Health $16,032.00 Corporate Sponsorships Science Center at San Antonio Univ of Texas Health $75,000.00 Educational Grants Science Center at San Antonio Univ of Texas Health $3,000.00 Educational Grants Science Center at San Antonio Univ of Texas M D Anderson $10,000.00 Educational Grants Cancer Center Univ of Texas Southwestern $55,000.00 Fellowships and Med Center Scholarships Univ of Texas Southwestern $2,000.00 Educational Grants Med Center Univ of Texas Southwestern $55,000.00 Educational Grants Med Center Univ of The State of New $50,000.00 Educational Grants York Univ at Buffalo Univ of Toledo $2,000.00 Educational Grants Universidad Central Del $7,500.00 Educational Grants Caribe School of Medicine Universidad Central Del $11,205.00 Educational Grants Caribe School of Medicine Universidad Central Del $12,000.00 Educational Grants Caribe School of Medicine Universidad Central Del $12,000.00 Educational Grants Caribe School of Medicine Universidad Central Del ($308.75) Educational Grants Caribe School of Medicine Universidad Central Del $7,500.00 Educational Grants Caribe School of Medicine Universidad Central Del $15,000.00 Educational Grants Caribe School of Medicine Universidad Central Del $15,000.00 Educational Grants Caribe School of Medicine Universidad Central Del $24,939.25 Educational Grants Caribe School of Medicine Universidad Central Del $10,000.00 Educational Grants Caribe School of Medicine Universidad Central Del $15,000.00 Educational Grants Caribe School of Medicine Universidad Central Del ($3,795.00) Educational Grants Caribe School of Medicine Universidad Central Del ($3,460.75) Educational Grants Caribe School of Medicine University of Alabama at ($186.25) Educational Grants Birmingham Hospital University of Alabama at $40,000.00 Fellowships and Birmingham Hospital Scholarships University of California $40,000.00 Fellowships and Irvine Scholarships University of California $40,000.00 Fellowships and Irvine Scholarships University of Colorado $1,000.00 Charitable Donations Foundation University of Connecticut $12,000.00 Fellowships and Health Science Center Scholarships University of Connecticut $40,000.00 Fellowships and Health Science Center Scholarships University of Connecticut ($774.73) Fellowships and Health Science Center Scholarships University of Edinburgh Usa $1,000.00 Charitable Donations Development Trust Inc. University of Illinois-- $82,092.00 Fellowships and office of Business and Scholarships Financial Services University of Illinois-- $79,559.00 Fellowships and office of Business and Scholarships Financial Services University of Rochester $40,000.00 Fellowships and Scholarships University of Sheffield in $1,000.00 Charitable Donations America Inc. University of Washington $40,000.00 Fellowships and Medical Center Scholarships University of Washington ($255.67) Educational Grants Medical Center Upstage Lung Cancer $5,000.00 Charitable Donations Urology Center of Colorado $10,000.00 Corporate Sponsorships Foundation US Too International $25,000.00 Corporate Sponsorships US Too International $1,500.00 Corporate Sponsorships Valley Childrens Hospital $4,000.00 Educational Grants Foundation Valley Medial Center $5,000.00 Corporate Sponsorships Foundation Vanderbilt Univ By and $5,000.00 Corporate Sponsorships Through Its Medical Center Vanderbilt Univ By and $12,500.00 Fellowships and Through Its Medical Center Scholarships Vanderbilt Univ By and $5,000.00 Educational Grants Through Its Medical Center Vanderbilt Univ By and $10,000.00 Educational Grants Through Its Medical Center VHA Inc. $35,000.00 Corporate Sponsorships Vindico Med Education $25,000.00 Educational Grants Vindico Med Education $50,000.00 Educational Grants Vindico Med Education $95,000.00 Educational Grants Vindico Med Education $75,000.00 Educational Grants Vindico Med Education $50,000.00 Educational Grants Virginia Association of $2,500.00 Corporate Sponsorships Health Plans Virginia Commonwealth Univ $2,500.00 Corporate Sponsorships School of Medicine Washington and Lee $1,000.00 Charitable Donations University Washington Hospital Center $10,000.00 Educational Grants Corp Washington Rheumatology $50,000.00 Corporate Sponsorships Alliance Washington Univ in St Louis $5,000.00 Educational Grants Washington Univ in St Louis $1,600.00 Fellowships and Scholarships Washington Univ in St Louis $40,000.00 Fellowships and Scholarships Webmd Global LLC ($500.00) Educational Grants Webmd Global LLC $75,000.00 Educational Grants Webmd Global LLC $146,500.00 Educational Grants Webmd Global LLC $340,000.00 Educational Grants Webmd Global LLC $100,000.00 Educational Grants Webmd Global LLC $150,000.00 Educational Grants Webmd Global LLC $105,000.00 Educational Grants Webmd Global LLC $90,000.00 Educational Grants Webmd Global LLC $150,000.00 Educational Grants Webmd Global LLC $300,000.00 Educational Grants Webmd Global LLC $600,000.00 Educational Grants Webmd Global LLC $250,000.00 Educational Grants Western Pennsylvania $5,000.00 Fellowships and Hospital forbes Regional Scholarships Campus Western Pennsylvania ($1,502.07) Fellowships and Hospital forbes Regional Scholarships Campus Western States Pharmacy $3,250.00 Corporate Sponsorships Conference for Pharmacy Residents Fellowships and Preceptors Wisconsin Chapter of The $5,000.00 Corporate Sponsorships American College of Healthcare Executives Wisconsin Collaborative for $2,650.00 Corporate Sponsorships Healthcare Quality Wisconsin Dairyland Chapter $2,000.00 Corporate Sponsorships of Healthcare Information and Management Systems Society (HIMSS) Wisconsin Rheumatology $10,000.00 Corporate Sponsorships Association Wj Weiser Association $5,000.00 Corporate Sponsorships Management Inc. World Parkinson Coalition $5,000.00 Charitable Donations Inc. Yale Univ $5,000.00 Educational Grants Young Survival Coalition $25,000.00 Corporate Sponsorships Zebrafish Disease Models $10,000.00 Educational Grants Society Zero The Project To End $270,000.00 Corporate Sponsorships Prostate Cancer Zero The Project To End $12,000.00 Corporate Sponsorships Prostate Cancer ------------------------------------------------------------------------ Grants and Donations Report--2018 (Parentheses represent refunds of previously disclosed payments) Report as of 3/31/3019 ------------------------------------------------------------------------ Recipient Payment Amount Purpose ------------------------------------------------------------------------ 50 Hoops $25,000.00 Educational Grants 50 Hoops $10,000.00 Patient Support A and R Educational Group $80,350.00 Corporate Sponsorships LLC A and R Educational Group $4,500.00 Corporate Sponsorships LLC AAPS $50,000.00 Corporate Sponsorships Aasld Foundation (American $500,000.00 Charitable Donations Association for The Study of Liver Disease) Aasld Foundation (American $250,000.00 Charitable Donations Association for The Study of Liver Disease) Academia Puertorriquena DE $4,500.00 Corporate Sponsorships Neurologia Academic Cme LLC $45,000.00 Educational Grants Academy of Managed Care $40,000.00 Corporate Sponsorships Pharmacy Academy of Managed Care $27,000.00 Corporate Sponsorships Pharmacy Academy of Managed Care $32,000.00 Corporate Sponsorships Pharmacy Academy of Managed Care $30,000.00 Corporate Sponsorships Pharmacy Advanced Medical Education $2,500.00 Corporate Sponsorships Consultants, Corp. Advanced Urology Institute $10,000.00 Corporate Sponsorships Education and General Fund Advances in Cosmetic and $75,000.00 Corporate Sponsorships Med Dermatology Inc. Advances in Cosmetic and $75,000.00 Corporate Sponsorships Med Dermatology Inc. Advances in Cosmetic and $75,000.00 Corporate Sponsorships Med Dermatology Inc. Adventist Health System-- $15,000.00 Corporate Sponsorships Sunbelt Inc. Aesthetic Dermatology $7,500.00 Corporate Sponsorships Symposia AIDS Connecticut $5,000.00 Corporate Sponsorships AIDS Foundation of Chicago $10,000.00 Corporate Sponsorships AIDS Foundation of Chicago $10,000.00 Charitable Donations AIDS Institute $10,000.00 Corporate Sponsorships AIDS Institute $7,500.00 Corporate Sponsorships AIDS Support Network $2,000.00 Corporate Sponsorships Aimed Alliance $20,000.00 Corporate Sponsorships Alabama Academy of $1,200.00 Corporate Sponsorships Neurology Alabama Associate of Center $5,000.00 Corporate Sponsorships Plans Alabama Dermatology Society $50,000.00 Corporate Sponsorships Alabama Society of $750.00 Corporate Sponsorships Dermatology Professionals Albert Einstein College of $10,000.00 Educational Grants Medicine Division of Dermatology Albert Einstein College of $50,000.00 Educational Grants Medicine of Yeshiva Univ Albert Einstein College of $45,000.00 Educational Grants Medicine of Yeshiva Univ Alliance for Aging Research $5,000.00 Corporate Sponsorships Alsac St Jude Childrens $15,000.00 Charitable Donations Research Hospital Alzheimers Association $2,500.00 Corporate Sponsorships Greater Illinois Chapter Alzheimers Disease and $100,000.00 Corporate Sponsorships Related Disorders Association Inc. Alzheimers Disease and $10,000.00 Charitable Donations Related Disorders Association Inc. American Academy of $40,000.00 Educational Grants Dermatology American Academy of $10,000.00 Charitable Donations Dermatology American Academy of $7,500.00 Corporate Sponsorships Dermatology American Academy of $300,000.00 Corporate Sponsorships Dermatology American Academy of $50,000.00 Charitable Donations Dermatology American Academy of $50,000.00 Educational Grants Dermatology American Academy of Family $19,000.00 Educational Grants Physicians American Academy of $30,000.00 Educational Grants Neurology Institute American Academy of $40,050.00 Corporate Sponsorships Neurology Institute American Academy of $38,220.00 Corporate Sponsorships Neurology Institute American Academy of $100,000.00 Fellowships and Neurology Institute Scholarships American Academy of $16,470.00 Corporate Sponsorships Neurology Institute American Academy of $24,112.40 Corporate Sponsorships Ophthalmology Aao American Academy of $15,000.00 Corporate Sponsorships Pediatrics American Academy of $14,000.00 Corporate Sponsorships Pediatrics American Academy of $95,000.00 Educational Grants Physician Assistants American Association of $5,000.00 Educational Grants Clinical Endocrinologists New Jersey Chapter American Association of $18,000.00 Educational Grants Clinical Endocrinologists New Jersey Chapter American Association for $5,000.00 Educational Grants Accreditation of Laboratory Animal Care International (Aaalac International American Association for $40,000.00 Fellowships and Cancer Research Scholarships American Association for $25,000.00 Patient Support Cancer Research American Association for $25,000.00 Educational Grants Cancer Research American Association for $10,000.00 Educational Grants Cancer Research American Association for $25,000.00 Charitable Donations Cancer Research American Association for $10,000.00 Educational Grants Cancer Research American Association for $20,000.00 Educational Grants Cancer Research American Association for $5,000.00 Educational Grants Cancer Research American Association for $10,000.00 Educational Grants Cancer Research American Association for $5,000.00 Educational Grants Cancer Research American Association for $5,000.00 Educational Grants Cancer Research American Association for $25,000.00 Educational Grants Cancer Research American Association for $25,000.00 Educational Grants Cancer Research American Association for $75,000.00 Educational Grants Cancer Research American Association for $20,000.00 Charitable Donations Laboratory Animal Science American Association for $10,000.00 Charitable Donations The Study of Liver Disease American Association of $200,000.00 Patient Support Clinical Endocrinologists Inc. American Association of $15,200.00 Corporate Sponsorships Gynecologic Laparoscopists Inc. American Association of $50,000.00 Educational Grants Nurse Practitioners American Brain Tumor $50,000.00 Fellowships and Association Scholarships American Brain Tumor $2,500.00 Charitable Donations Association American Brain Tumor $10,000.00 Patient Support Association American Brain Tumor $10,000.00 Corporate Sponsorships Association American Brain Tumor $60,000.00 Corporate Sponsorships Association American Brain Tumor $3,400.00 Corporate Sponsorships Association American Brain Tumor $10,000.00 Patient Support Association American Brain Tumor $10,000.00 Patient Support Association American Brain Tumor $5,000.00 Corporate Sponsorships Association American Brain Tumor $50,000.00 Fellowships and Association Scholarships American Brain Tumor $22,500.00 Corporate Sponsorships Association American Brain Tumor $25,000.00 Corporate Sponsorships Association American Brain Tumor $50,000.00 Corporate Sponsorships Association American Cancer Society $5,000.00 Corporate Sponsorships American Cancer Society $1,500.00 Corporate Sponsorships American Cancer Society $10,000.00 Corporate Sponsorships American Cancer Society $10,000.00 Charitable Donations American Cancer Society $2,500.00 Corporate Sponsorships American Cancer Society $10,000.00 Corporate Sponsorships American Cancer Society $5,000.00 Corporate Sponsorships American Cancer Society $2,500.00 Corporate Sponsorships American Cancer Society $5,000.00 Corporate Sponsorships American Cancer Society $10,000.00 Corporate Sponsorships American Cancer Society $5,000.00 Corporate Sponsorships American Cancer Society $5,000.00 Corporate Sponsorships American Cancer Society $2,500.00 Corporate Sponsorships American Cancer Society $2,500.00 Corporate Sponsorships American Cancer Society $2,500.00 Corporate Sponsorships American Cancer Society $2,500.00 Corporate Sponsorships American Cancer Society $2,500.00 Corporate Sponsorships American Cancer Society $2,500.00 Corporate Sponsorships American Cancer Society $5,000.00 Corporate Sponsorships American Cancer Society $12,000.00 Corporate Sponsorships American Cancer Society $3,500.00 Corporate Sponsorships American Cancer Society $10,000.00 Corporate Sponsorships American Cancer Society $50,000.00 Corporate Sponsorships American Cancer Society $50,000.00 Corporate Sponsorships American Chemist Society $3,000.00 Educational Grants American Chemist Society $2,500.00 Educational Grants American Chemist Society $1,500.00 Educational Grants American Chemist Society $3,000.00 Educational Grants American College of $10,000.00 Corporate Sponsorships Gastroenterology American College of $90,000.00 Corporate Sponsorships Gastroenterology American College of $90,000.00 Corporate Sponsorships Gastroenterology American College of $60,000.00 Corporate Sponsorships Gastroenterology American College of $60,000.00 Corporate Sponsorships Gastroenterology American College of $450,000.00 Charitable Donations Gastroenterology American College of $100,000.00 Corporate Sponsorships Gastroenterology American College of $125,000.00 Corporate Sponsorships Gastroenterology American College of $30,000.00 Charitable Donations Laboratory Animal Medicine American College of $32,500.00 Corporate Sponsorships Obstetricians and Gynecologists American College of $25,000.00 Corporate Sponsorships Osteopathic Family Physicians of California American College of $35,000.00 Corporate Sponsorships Osteopathic Obstetricians and Gynecologists American College of $57,000.00 Corporate Sponsorships Physician Foundation American College of $25,000.00 Educational Grants Rheumatology American College of $70,000.00 Corporate Sponsorships Rheumatology American College of $25,000.00 Educational Grants Rheumatology American College of $35,000.00 Educational Grants Rheumatology American College of $50,000.00 Educational Grants Rheumatology American College of $50,000.00 Corporate Sponsorships Rheumatology American College of $2,000,000.00 Corporate Sponsorships Rheumatology Research and Education Foundation American Congress of $3,000.00 Corporate Sponsorships Obstetricians and Gynecologists American Congress of $9,500.00 Corporate Sponsorships Obstetricians and Gynecologists American Congress of $10,000.00 Corporate Sponsorships Obstetricians and Gynecologists American Congress of $2,250.00 Corporate Sponsorships Obstetricians and Gynecologists American Congress of $25,000.00 Educational Grants Obstetricians and Gynecologists--Hawaii Section District Viii American Congress of $32,500.00 Corporate Sponsorships Obstetricians and Gynecologists--Hawaii Section District Viii American Congress of $15,000.00 Corporate Sponsorships Obstetricians and Gynecologists--Hawaii Section District Viii American Congress of $38,400.00 Corporate Sponsorships Obstetricians and Gynecologists--Hawaii Section District Viii American Congress of $2,500.00 Corporate Sponsorships Obstetricians and Gynecologists Montana Section American $278,000.00 Educational Grants Gastroenterological Association Institute American $46,325.00 Corporate Sponsorships Gastroenterological Association Institute American $50,000.00 Corporate Sponsorships Gastroenterological Association Institute American $90,000.00 Corporate Sponsorships Gastroenterological Association Institute American $200,000.00 Educational Grants Gastroenterological Association Institute American $40,000.00 Educational Grants Gastroenterological Association Institute American Gastrointestinal ($2,094.95) Educational Grants Association American Kdny Fund $5,000.00 Corporate Sponsorships American Liver Foundation $300,000.00 Corporate Sponsorships American Liver Foundation $1,000.00 Corporate Sponsorships American Liver Foundation $7,500.00 Corporate Sponsorships American Liver Foundation $2,500.00 Corporate Sponsorships American Liver Foundation $10,000.00 Educational Grants American Liver Foundation $2,500.00 Corporate Sponsorships American Liver Foundation $5,000.00 Corporate Sponsorships American Liver Foundation $50,000.00 Educational Grants American Liver Foundation $86,000.00 Corporate Sponsorships American Liver Foundation $25,000.00 Educational Grants American Med Group $5,022.40 Corporate Sponsorships Associate American Med Group $5,022.40 Corporate Sponsorships Associate American Med Group $5,022.40 Corporate Sponsorships Associate American Med Group $5,022.40 Corporate Sponsorships Associate American Med Group $5,022.40 Corporate Sponsorships Associate American Military Partner $25,000.00 Corporate Sponsorships Association American Military Partner $25,000.00 Corporate Sponsorships Association American National Red Cross $1,000.00 Corporate Sponsorships and Its Constituent Chapters and Branches American Neuro Associate $40,000.00 Educational Grants American Pancreatic $25,000.00 Charitable Donations Associate American Pancreatic $75,000.00 Educational Grants Associate American Pancreatic $60,000.00 Corporate Sponsorships Associate American Pancreatic $70,000.00 Corporate Sponsorships Associate American Parkinson Disease $3,000.00 Corporate Sponsorships Association American Parkinson Disease $5,000.00 Corporate Sponsorships Association American Parkinson Disease $75,000.00 Corporate Sponsorships Association American Parkinson Disease $25,000.00 Corporate Sponsorships Association American Parkinson Disease $2,000.00 Corporate Sponsorships Association American Parkinson Disease $5,000.00 Corporate Sponsorships Association American Parkinson Disease $4,000.00 Corporate Sponsorships Association American Parkinson Disease $10,000.00 Educational Grants Association American Pharmacists $15,000.00 Corporate Sponsorships Association (Apha) American Red Cross of $10,000.00 Charitable Donations Greater Chicago American Society for $40,000.00 Corporate Sponsorships Reproductive Medicine American Society for $10,000.00 Corporate Sponsorships Reproductive Medicine American Society for $6,000.00 Corporate Sponsorships Reproductive Medicine American Society of $17,500.00 Corporate Sponsorships Anesthesiologists American Society of $15,000.00 Educational Grants Hematology American Society of $544,550.00 Corporate Sponsorships Hematology American Society of $60,000.00 Educational Grants Hematology American Society of $50,000.00 Fellowships and Hematology Scholarships American Society of $20,000.00 Educational Grants Hematology American Society of $50,000.00 Educational Grants Hematology American Statistical $26,500.00 Corporate Sponsorships Associate American Thyroid Associate $30,000.00 Educational Grants Inc. American Uroligical $3,500.00 Corporate Sponsorships Associate Northeastern Section American Urological $25,000.00 Corporate Sponsorships Associate Education and Research Inc. American Urological $50,000.00 Charitable Donations Associate Education and Research Inc. American Urological $20,000.00 Educational Grants Associate Education and Research Inc. American Urological $50,000.00 Educational Grants Associate Education and Research Inc. American Urological $10,000.00 Corporate Sponsorships Associate Inc. Western Section American Urological $35,000.00 Corporate Sponsorships Associate Inc. Western Section American Urological $2,000.00 Corporate Sponsorships Association--New York Section American Urological $25,000.00 Corporate Sponsorships Association--Southeast Section American Urological $5,800.00 Corporate Sponsorships Association--Southeast Section American Urological $10,000.00 Charitable Donations Association Foundation Americans for Med Progress $90,000.00 Charitable Donations Americas Hepato--Pancreato-- $35,750.00 Corporate Sponsorships Biliary A Angel Foundation $5,000.00 Corporate Sponsorships Angel Foundation $10,000.00 Corporate Sponsorships Angela Hospice Homecare $2,500.00 Charitable Donations Answer2cancer $3,000.00 Corporate Sponsorships Arizona State Association $3,500.00 Corporate Sponsorships of Physician Assistants Arizona United Rheumatology $10,000.00 Corporate Sponsorships Alliance--Aura Arkansas Prostate Cancer $2,000.00 Corporate Sponsorships Foundation Arkansas Rheumatology $10,000.00 Corporate Sponsorships Association Arkansas Urology Society $1,250.00 Corporate Sponsorships Arthritis Foundation $100,000.00 Fellowships and Scholarships Arthritis Foundation $25,000.00 Corporate Sponsorships Arthritis Foundation $175,000.00 Corporate Sponsorships Arthritis Foundation $40,000.00 Corporate Sponsorships Arthritis Foundation $2,000.00 Corporate Sponsorships Arthritis Foundation $25,000.00 Corporate Sponsorships Arthritis Foundation $5,000.00 Charitable Donations Arthritis Foundation $2,500.00 Patient Support Arthritis Foundation $5,000.00 Patient Support Arthritis Foundation $30,000.00 Corporate Sponsorships Arthritis Foundation $25,000.00 Corporate Sponsorships Arthritis Foundation $10,500.00 Patient Support Arthritis Foundation $20,000.00 Patient Support Arthritis Foundation $10,000.00 Charitable Donations Arthritis Foundation $7,500.00 Patient Support Arthritis Foundation $30,000.00 Corporate Sponsorships Arthritis Foundation $2,500.00 Corporate Sponsorships Arthritis Foundation $10,000.00 Corporate Sponsorships Arthritis Foundation $1,595.00 Patient Support Arthritis Foundation $1,650.00 Corporate Sponsorships Arthritis Foundation $5,000.00 Corporate Sponsorships Arthritis Foundation $10,000.00 Corporate Sponsorships Arthritis Foundation $10,000.00 Corporate Sponsorships Arthritis Foundation $5,000.00 Corporate Sponsorships Arthritis Foundation $5,000.00 Corporate Sponsorships Arthritis Foundation $2,500.00 Corporate Sponsorships Arthritis Foundation $300.00 Corporate Sponsorships Arthritis Foundation $2,500.00 Corporate Sponsorships Arthritis Foundation $3,000.00 Corporate Sponsorships Arthritis Foundation $5,000.00 Corporate Sponsorships Arthritis Foundation $250,000.00 Corporate Sponsorships Arthritis Foundation $400,000.00 Corporate Sponsorships Arthritis Foundation $5,000.00 Educational Grants Arthritis Foundation $40,000.00 Corporate Sponsorships Arthritis Foundation $25,000.00 Corporate Sponsorships Arthritis Foundation $259,000.00 Corporate Sponsorships Arthritis Foundation $100,000.00 Fellowships and Scholarships Arthritis Foundation $2,000.00 Corporate Sponsorships Arthritis Foundation $175,000.00 Corporate Sponsorships Arthritis Foundation $300,000.00 Corporate Sponsorships Arthritis Patient Services $19,500.00 Charitable Donations Arts of Healing Foundation $2,500.00 Corporate Sponsorships ASCO Conquer Cancer $100,000.00 Charitable Donations Foundation ASCO Conquer Cancer $40,000.00 Educational Grants Foundation ASCO Conquer Cancer $60,000.00 Fellowships and Foundation Scholarships ASCO Conquer Cancer $75,000.00 Fellowships and Foundation Scholarships ASCO Conquer Cancer $30,000.00 Educational Grants Foundation ASCO Conquer Cancer $30,000.00 Fellowships and Foundation Scholarships ASCO Conquer Cancer $10,000.00 Educational Grants Foundation ASCO Conquer Cancer $30,000.00 Educational Grants Foundation ASCO Conquer Cancer $30,000.00 Educational Grants Foundation ASCO Conquer Cancer $60,000.00 Educational Grants Foundation ASCO Conquer Cancer $50,000.00 Educational Grants Foundation ASCO Conquer Cancer $25,000.00 Educational Grants Foundation ASCO Conquer Cancer $100,000.00 Charitable Donations Foundation ASCO Conquer Cancer $30,000.00 Fellowships and Foundation Scholarships ASCO Conquer Cancer $60,000.00 Fellowships and Foundation Scholarships ASCO Conquer Cancer $75,000.00 Fellowships and Foundation Scholarships ASCO Conquer Cancer $22,000.00 Educational Grants Foundation ASHP Foundation $75,000.00 Fellowships and Scholarships Aspen Cancer Conference $10,000.00 Educational Grants Inc. Associate de Enfermeria $6,700.00 Corporate Sponsorships Oncologica y Hematologica de Puerto Rico Inc. Associate de $10,000.00 Corporate Sponsorships Gastroenterologia y Hepatologia Pediatrica de Puerto Rico Aghppr Associate de Hematologia y $5,000.00 Corporate Sponsorships Oncologia Medica de Puerto Rico Associate de Hematologia y $12,000.00 Corporate Sponsorships Oncologia Medica de Puerto Rico Associate de Hematologia y $3,000.00 Corporate Sponsorships Oncologia Medica de Puerto Rico Associate de Hematologia y $11,000.00 Corporate Sponsorships Oncologia Medica de Puerto Rico Associate de Reumatologos $15,000.00 Corporate Sponsorships de Puerto Rico Associate Medicos Pediatras $6,500.00 Corporate Sponsorships Region Este Ampre Associate Medicos Pediatras $6,500.00 Corporate Sponsorships Region Este Ampre Associate of Physician $2,950.00 Corporate Sponsorships Assistants in Oncology Inc. Associate of Physician $35,000.00 Corporate Sponsorships Assistants in Oncology Inc. Associate of Professors of $50,000.00 Corporate Sponsorships Gyn and Obstetrician Association of Community $30,000.00 Educational Grants Cancer Centers (Accc) Association of $5,000.00 Corporate Sponsorships Frontotemporal Degeneration Association of Idaho $1,500.00 Corporate Sponsorships Rheumatologists Inc. Association of Physicians $1,500.00 Corporate Sponsorships of Pakistani Descent of North America (Appna)--New York Chapter Association of VA $15,500.00 Corporate Sponsorships Hematology Oncology Association of Women in $40,000.00 Corporate Sponsorships Rheumatology Association of Women in $40,000.00 Corporate Sponsorships Rheumatology Awesome Enablers LLC $250,000.00 Corporate Sponsorships Awesome Enablers LLC $250,000.00 Corporate Sponsorships Baylor College Medicine $100,000.00 Fellowships and Infusion Dis Scholarships Baylor Scott and White $5,000.00 Educational Grants Health Bellaire Crohns and Colitis $15,000.00 Corporate Sponsorships Foundation Bellaire Crohns and Colitis $5,000.00 Corporate Sponsorships Foundation Bellaire Crohns and Colitis $400,000.00 Corporate Sponsorships Foundation Bendcare $434,000.00 Corporate Sponsorships Beth Israel Deaconess $40,000.00 Fellowships and Medical Center Scholarships Beth Israel Deaconess $40,000.00 Fellowships and Medical Center Scholarships Beth Israel Deaconess $3,500.00 Educational Grants Medical Center Betty and Milton Katz $1,500.00 Corporate Sponsorships Jewish Community Center Bexar County Physician $6,250.00 Corporate Sponsorships Assistant Society Big Brothers Big Sisters of $20,000.00 Charitable Donations Metro Chicago Bio Ascend LLC $50,000.00 Corporate Sponsorships Bio Ascend LLC $25,000.00 Corporate Sponsorships Biomod Foundation $1,500.00 Corporate Sponsorships Biotechnology Industry $155,000.00 Corporate Sponsorships Organization Biotechnology Industry $290,000.00 Corporate Sponsorships Organization Biotechnology Industry $25,000.00 Corporate Sponsorships Organization Biotechnology Industry $56,000.00 Corporate Sponsorships Organization Black Health Matters $5,000.00 Corporate Sponsorships Board of Trustees of The $1,500.00 Corporate Sponsorships Univ of Illinois Bonnie J Addario Lung $50,000.00 Patient Support Cancer Foundation Bonnie J Addario Lung $5,000.00 Corporate Sponsorships Cancer Foundation Borland Groover Clinic $750.00 Corporate Sponsorships Boston College School of $10,000.00 Corporate Sponsorships Nursing Boston Society Inc. $3,000.00 Educational Grants Boston Taiwanese $2,500.00 Educational Grants Biotechnology Association Inc. Brian Grant Foundation $85,000.00 Educational Grants Brian Grant Foundation $15,000.00 Corporate Sponsorships Brigham and Women's $7,000.00 Educational Grants Hospital, Inc. Business Health Coalition $5,000.00 Corporate Sponsorships Foundation California Associate of $10,000.00 Corporate Sponsorships Physician Groups California Life Sciences $20,000.00 Corporate Sponsorships Association California Life Sciences $1,500.00 Corporate Sponsorships Association Cancer and Leukemia Group B $30,000.00 Educational Grants Foundation Cancer and Leukemia Group B $50,000.00 Fellowships and Foundation Scholarships Cancer Care $25,000.00 Charitable Donations Cancer Care $75,000.00 Charitable Donations Cancer Care $25,000.00 Educational Grants Cancer Care $25,000.00 Educational Grants Cancer Care $100,000.00 Educational Grants Cancer Care $100,000.00 Educational Grants Cancer Foundation for New $2,500.00 Corporate Sponsorships Mexico Cancer Foundation for New $2,500.00 Corporate Sponsorships Mexico Cancer Molecular Thrpt $5,000.00 Educational Grants Cancer Research Institute $10,000.00 Educational Grants Cancer Research Institute $40,000.00 Corporate Sponsorships Cancer Support Community $75,000.00 Educational Grants Cancer Support Community $75,000.00 Educational Grants Cancer Wellness Center $5,000.00 Corporate Sponsorships Cancercare Co-Payment $5,000,000.00 Charitable Donations Assistance Foundation Captis Health $3,000.00 Corporate Sponsorships Cardinal Health $100,000.00 Corporate Sponsorships Cardinal Health $105,000.00 Corporate Sponsorships Carevive Systems, Inc. $75,000.00 Educational Grants Carevive Systems, Inc. $75,000.00 Educational Grants Carevive Systems, Inc. $75,000.00 Educational Grants Carevive Systems, Inc. $125,000.00 Educational Grants Caring Ambassadors Program $5,000.00 Corporate Sponsorships Inc. Caring Ambassadors Program $10,000.00 Corporate Sponsorships Inc. Caring Ambassadors Program $10,000.00 Corporate Sponsorships Inc. Caring Ambassadors Program $50,000.00 Charitable Donations Inc. Caring Ambassadors Program $10,000.00 Charitable Donations Inc. Carti Foundation $10,000.00 Corporate Sponsorships Cascade Aids Project $5,000.00 Corporate Sponsorships Case Western Reserve Univ $20,000.00 Fellowships and Scholarships Cedar Rapids Metro $2,000.00 Corporate Sponsorships Parkinsons Association Cedars--Sinai Med Center $40,000.00 Fellowships and Scholarships Cedars--Sinai Med Center $8,000.00 Educational Grants Central Brain Tumor $30,000.00 Educational Grants Registry of The United States Central Savannah River Area $1,000.00 Corporate Sponsorships Csra Parkinson Support Group Chicago Gynecological $8,000.00 Corporate Sponsorships Society Chicago Urological Soctiey $12,000.00 Corporate Sponsorships Childrens Digestive Health $42,428.00 Corporate Sponsorships and Nutrition Foundation Childrens Hospital of $2,000.00 Corporate Sponsorships Wisconsin Children's Skin Disease $600.00 Corporate Sponsorships Foundation Childrens Treehouse $10,000.00 Charitable Donations Foundation Chimp Haven $15,000.00 Charitable Donations Chinese American $3,600.00 Corporate Sponsorships Biopharmaceutical Society Chris Elliott Fund $10,000.00 Charitable Donations Chris Elliott Fund $10,000.00 Charitable Donations Chris Elliott Fund $10,000.00 Charitable Donations Chris Elliott Fund $25,000.00 Corporate Sponsorships Chris Elliott Fund $50,000.00 Charitable Donations Chris Elliott Fund $40,000.00 Educational Grants Chris Elliott Fund $10,000.00 Corporate Sponsorships Chris Elliott Fund $10,000.00 Corporate Sponsorships Chris Elliott Fund $20,000.00 Corporate Sponsorships Chris Elliott Fund $20,000.00 Corporate Sponsorships Chris Elliott Fund $25,000.00 Corporate Sponsorships Chris Elliott Fund $10,000.00 Corporate Sponsorships Christ Hospital Foundation $5,000.00 Corporate Sponsorships Chronic Liver Disease $450,000.00 Educational Grants Foundation Chronic Liver Disease $75,000.00 Corporate Sponsorships Foundation Chronic Liver Disease $75,000.00 Corporate Sponsorships Foundation Chronic Liver Disease $90,000.00 Corporate Sponsorships Foundation Chronic Lymphoytic Leukemia $50,000.00 Charitable Donations Society Inc. Chronic Lymphoytic Leukemia $25,075.00 Patient Support Society Inc. Chronic Lymphoytic Leukemia $75,000.00 Patient Support Society Inc. Chronic Lymphoytic Leukemia $50,000.00 Patient Support Society Inc. Chronic Lymphoytic Leukemia $35,000.00 Patient Support Society Inc. Chronic Lymphoytic Leukemia $75,000.00 Patient Support Society Inc. Cincinnati Childrens $40,000.00 Fellowships and Hospital Medical Center Scholarships City of Hope National Med $50,000.00 Educational Grants Center Cleveland Clinic ($3,131.07) Educational Grants Educational Foundation Cleveland Clinic $5,000.00 Educational Grants Educational Foundation Cleveland Clinic ($13,876.68) Educational Grants Educational Foundation Cleveland Clinic $50,000.00 Educational Grants Educational Foundation Cleveland Clinic ($7,563.37) Educational Grants Educational Foundation Cleveland Clinic $50,000.00 Educational Grants Educational Foundation Cleveland Clinic $20,000.00 Educational Grants Educational Foundation Cleveland Clinic $5,000.00 Educational Grants Educational Foundation Cleveland Clinic $50,000.00 Educational Grants Educational Foundation Cleveland Clinic $50,000.00 Educational Grants Educational Foundation Cleveland Clinic $25,000.00 Corporate Sponsorships Educational Foundation Cleveland Clinic Foundation $55,000.00 Fellowships and Scholarships Cleveland Clinic Minority $25,000.00 Corporate Sponsorships Mens Health Center Clinical Care Optn LLC $5,000.00 Educational Grants Clinical Care Optn LLC $35,000.00 Educational Grants Clinical Care Optn LLC $75,000.00 Educational Grants Clinical Care Optn LLC $35,000.00 Educational Grants Clinical Care Optn LLC $50,000.00 Educational Grants Clinical Care Optn LLC $35,000.00 Educational Grants Clinical Care Optn LLC ($35,000.00) Educational Grants Clinical Care Optn LLC $25,000.00 Educational Grants Clinical Care Optn LLC $75,000.00 Educational Grants Clinical Care Optn LLC $120,000.00 Educational Grants Clinical Care Optn LLC $25,000.00 Educational Grants Clinical Care Optn LLC $25,000.00 Educational Grants Clinical Care Optn LLC $50,000.00 Educational Grants Clinical Care Optn LLC $50,000.00 Educational Grants Clinical Care Optn LLC $75,000.00 Educational Grants Clinical Care Optn LLC $75,000.00 Educational Grants Clinical Care Optn LLC $95,000.00 Educational Grants CLL Global Research $35,000.00 Patient Support Foundation CLL Global Research $35,000.00 Educational Grants Foundation Club DE oficiales DE LA $495.00 Charitable Donations Policia DE Puerto Rico Inc. Coalition for Prevention of $5,000.00 Corporate Sponsorships Colorectal Cancer in Puerto Rico Coalition of Texans With $5,000.00 Corporate Sponsorships Disabilities Coalition of Texans With $5,000.00 Corporate Sponsorships Disabilities Cockerell Educational $25,000.00 Corporate Sponsorships Foundation Cockerell Educational $30,000.00 Corporate Sponsorships Foundation Cody Dieruf Benefit $5,000.00 Charitable Donations Foundation Colegio DE Farmaceuticos DE $4,000.00 Corporate Sponsorships Puerto Rico Colegio DE Farmaceuticos DE $5,000.00 Corporate Sponsorships Puerto Rico Colegio DE Profesionales DE $2,000.00 Corporate Sponsorships LA Enfermeria DE Puerto Rico Inc. Colegio DE Profesionales DE $3,000.00 Corporate Sponsorships LA Enfermeria DE Puerto Rico Inc. Colegio DE Profesionales DE $3,000.00 Corporate Sponsorships LA Enfermeria DE Puerto Rico Inc. Collaborative Alliance for $30,000.00 Educational Grants Pancreatic Education and Research (Caper) Collaborative Alliance for $30,000.00 Fellowships and Pancreatic Education and Scholarships Research (Caper) Collaborative Alliance for $6,000.00 Fellowships and Pancreatic Education and Scholarships Research (Caper) College of American $5,065.00 Corporate Sponsorships Pathologists College of Lake County $1,000.00 Charitable Donations Colorado American Congress $10,000.00 Corporate Sponsorships of Obstetrician Gyn Colorado Section Columbia Univ Med Center $5,000.00 Educational Grants Columbia Univ Med Center $75,000.00 Fellowships and Scholarships Community Center $10,000.00 Corporate Sponsorships Community Center $10,000.00 Corporate Sponsorships Community Foundation $5,000.00 Corporate Sponsorships Community Foundation $1,500.00 Corporate Sponsorships Community Initiatives $40,000.00 Corporate Sponsorships Community Initiatives $25,000.00 Patient Support Community Initiatives $1,500.00 Charitable Donations Community Liver Alliance $15,000.00 Corporate Sponsorships Community Liver Alliance $500.00 Corporate Sponsorships Community Liver Alliance $1,500.00 Corporate Sponsorships Community Oncology Alliance $20,000.00 Corporate Sponsorships Connecticut Dermatology $3,722.25 Corporate Sponsorships Society Connecticut Dermatology $3,500.00 Corporate Sponsorships Society Connecting To Cure Crohns $10,000.00 Corporate Sponsorships and Colitis Consortium of Multiple $59,150.00 Educational Grants Sclerosis Centers Consortium of Multiple ($452.00) Educational Grants Sclerosis Centers Consortium of Multiple ($341.36) Educational Grants Sclerosis Centers Continuing Educational $350,000.00 Educational Grants Alliance LLC Continuing Educational $375,000.00 Educational Grants Alliance LLC Continuing Educational ($623.00) Educational Grants Alliance LLC Continuing Educational $200,000.00 Educational Grants Alliance LLC Continuing Educational $75,000.00 Educational Grants Alliance LLC Continuing Educational $300,000.00 Educational Grants Alliance LLC Cornell Univ Weill Med $15,000.00 Educational Grants College Cornell Univ Weill Med $3,000.00 Educational Grants College Cornerstone Health Inc. $90,000.00 Educational Grants Cornerstone Health Inc. $50,000.00 Educational Grants Cradles To Crayons Inc. $300.00 Charitable Donations Cristo Rey St Martin $7,500.00 Corporate Sponsorships College Prep Crohns and Colitis $2,500.00 Corporate Sponsorships Foundation of America Crohns and Colitis $5,000.00 Corporate Sponsorships Foundation of America Crohns and Colitis $1,500.00 Corporate Sponsorships Foundation of America Crohns and Colitis $2,500.00 Corporate Sponsorships Foundation of America Crohns and Colitis $5,000.00 Corporate Sponsorships Foundation of America Crohns and Colitis $15,000.00 Corporate Sponsorships Foundation of America Crohns and Colitis $10,000.00 Corporate Sponsorships Foundation of America Crohns and Colitis $20,000.00 Charitable Donations Foundation of America Crohns and Colitis $40,000.00 Patient Support Foundation of America Crohns and Colitis $150,000.00 Corporate Sponsorships Foundation of America Crohns and Colitis $5,000.00 Corporate Sponsorships Foundation of America Crohns and Colitis $90,000.00 Patient Support Foundation of America Crohns and Colitis $250,000.00 Educational Grants Foundation of America Crohns and Colitis $2,500.00 Corporate Sponsorships Foundation of America Crohns and Colitis $25,000.00 Corporate Sponsorships Foundation of America Crohns and Colitis $1,000.00 Corporate Sponsorships Foundation of America Crohns and Colitis $1,000.00 Corporate Sponsorships Foundation of America Crohns and Colitis $2,500.00 Corporate Sponsorships Foundation of America Crohns and Colitis $3,500.00 Corporate Sponsorships Foundation of America Crohns and Colitis $3,000.00 Corporate Sponsorships Foundation of America Crohns and Colitis $25,000.00 Educational Grants Foundation of America Crohns and Colitis $25,000.00 Educational Grants Foundation of America Crohns and Colitis $25,000.00 Educational Grants Foundation of America Crohns and Colitis $10,000.00 Corporate Sponsorships Foundation of America Crohns and Colitis $2,500.00 Corporate Sponsorships Foundation of America Crohns and Colitis $5,000.00 Corporate Sponsorships Foundation of America Crohns and Colitis $5,000.00 Corporate Sponsorships Foundation of America Crohns and Colitis $2,500.00 Corporate Sponsorships Foundation of America Crohns and Colitis $5,000.00 Corporate Sponsorships Foundation of America Crohns and Colitis $7,500.00 Corporate Sponsorships Foundation of America Crohns and Colitis $5,000.00 Corporate Sponsorships Foundation of America Crohns and Colitis $5,000.00 Corporate Sponsorships Foundation of America Crohns and Colitis $1,000.00 Corporate Sponsorships Foundation of America Crohns and Colitis $25,000.00 Corporate Sponsorships Foundation of America Crohns and Colitis $1,500.00 Corporate Sponsorships Foundation of America Crohns and Colitis $2,500.00 Corporate Sponsorships Foundation of America Crohns and Colitis $3,500.00 Corporate Sponsorships Foundation of America Crohns and Colitis $2,500.00 Corporate Sponsorships Foundation of America Crohns and Colitis $5,000.00 Corporate Sponsorships Foundation of America Crohns and Colitis $7,500.00 Corporate Sponsorships Foundation of America Crohns and Colitis $10,000.00 Corporate Sponsorships Foundation of America Crohns and Colitis $10,000.00 Corporate Sponsorships Foundation of America Crohns and Colitis $25,000.00 Corporate Sponsorships Foundation of America Crohns and Colitis $250,000.00 Educational Grants Foundation of America Curators of The Univ of $1,000.00 Charitable Donations Missouri Curepsp Inc. $5,000.00 Corporate Sponsorships Curepsp Inc. $2,500.00 Patient Support Curepsp Inc. $30,000.00 Corporate Sponsorships Curepsp Inc. $45,500.00 Corporate Sponsorships Curepsp Inc. $30,000.00 Charitable Donations Curesearch for Childrens $15,000.00 Charitable Donations Cancer Cystic Fibrosis Foundation $1,500.00 Corporate Sponsorships Cystic Fibrosis Foundation $25,000.00 Corporate Sponsorships Cystic Fibrosis Foundation $2,000.00 Corporate Sponsorships Cystic Fibrosis Foundation $2,000.00 Corporate Sponsorships Cystic Fibrosis Foundation $1,750.00 Corporate Sponsorships Cystic Fibrosis Foundation $3,000.00 Corporate Sponsorships Cystic Fibrosis Foundation $5,000.00 Corporate Sponsorships Cystic Fibrosis Foundation $2,500.00 Corporate Sponsorships Cystic Fibrosis Foundation $2,500.00 Corporate Sponsorships Cystic Fibrosis Foundation $5,000.00 Corporate Sponsorships Cystic Fibrosis Foundation $1,500.00 Corporate Sponsorships Cystic Fibrosis Foundation $2,500.00 Corporate Sponsorships Cystic Fibrosis Foundation $2,500.00 Corporate Sponsorships Cystic Fibrosis Foundation $2,500.00 Corporate Sponsorships Cystic Fibrosis Foundation $1,000.00 Corporate Sponsorships Cystic Fibrosis Foundation $5,500.00 Corporate Sponsorships Cystic Fibrosis Foundation $2,500.00 Corporate Sponsorships Cystic Fibrosis Foundation $3,500.00 Corporate Sponsorships Cystic Fibrosis Foundation $500.00 Corporate Sponsorships Cystic Fibrosis Foundation $10,000.00 Charitable Donations Cystic Fibrosis Foundation $1,000.00 Corporate Sponsorships Cystic Fibrosis Foundation $2,500.00 Corporate Sponsorships Cystic Fibrosis Foundation $2,500.00 Corporate Sponsorships Cystic Fibrosis Foundation $6,000.00 Corporate Sponsorships Cystic Fibrosis Foundation $7,500.00 Corporate Sponsorships Cystic Fibrosis Foundation $7,500.00 Corporate Sponsorships Cystic Fibrosis Foundation $4,000.00 Corporate Sponsorships Cystic Fibrosis Foundation $250.00 Corporate Sponsorships Cystic Fibrosis Foundation $7,500.00 Corporate Sponsorships Cystic Fibrosis Foundation $2,500.00 Corporate Sponsorships Cystic Fibrosis Foundation $8,000.00 Corporate Sponsorships Cystic Fibrosis Foundation $12,500.00 Corporate Sponsorships Cystic Fibrosis Foundation $161,000.00 Corporate Sponsorships Cystic Fibrosis Foundation $5,000.00 Corporate Sponsorships Cystic Fibrosis Foundation $2,500.00 Corporate Sponsorships Cystic Fibrosis Foundation $2,500.00 Corporate Sponsorships Cystic Fibrosis Foundation $1,500.00 Corporate Sponsorships Cystic Fibrosis Foundation $1,000.00 Corporate Sponsorships Cystic Fibrosis Foundation $3,500.00 Corporate Sponsorships Cystic Fibrosis Foundation $5,000.00 Corporate Sponsorships Cystic Fibrosis Foundation $500.00 Corporate Sponsorships Cystic Fibrosis Foundation $750.00 Corporate Sponsorships Cystic Fibrosis Foundation $1,000.00 Corporate Sponsorships Cystic Fibrosis Foundation $2,500.00 Corporate Sponsorships Cystic Fibrosis Foundation $3,500.00 Corporate Sponsorships Cystic Fibrosis Foundation $10,000.00 Charitable Donations Cystic Fibrosis Foundation $750,000.00 Corporate Sponsorships Cystic Fibrosis Research $5,000.00 Corporate Sponsorships Fund Emilys Entourage Cystic Fibrosis Research $20,000.00 Corporate Sponsorships Inc. Cystic Fibrosis Research $3,000.00 Corporate Sponsorships Inc. Cystic Fibrosis Research $6,000.00 Corporate Sponsorships Inc. Cystic Fibrosis Research $7,000.00 Corporate Sponsorships Inc. Cystic Fibrosis Research $10,000.00 Corporate Sponsorships Inc. Cystic Fibrosis Research $12,000.00 Corporate Sponsorships Inc. Cystic Fibrosis Research $12,000.00 Corporate Sponsorships Inc. Dade County Medical $5,000.00 Educational Grants Association Dahshu $5,000.00 Corporate Sponsorships Dallas Area Parkinsonism $2,500.00 Corporate Sponsorships Society Dana Farber Cancer $25,000.00 Educational Grants Institute Dana Farber Cancer $100,000.00 Corporate Sponsorships Institute, Inc. Dava Oncology LP $37,500.00 Corporate Sponsorships Davis Phinney Foundation $30,000.00 Patient Support Davis Phinney Foundation $80,000.00 Corporate Sponsorships Davis Phinney Foundation $30,000.00 Patient Support Davis Phinney Foundation $15,000.00 Patient Support Davis Phinney Foundation $15,000.00 Educational Grants Davis Phinney Foundation $15,000.00 Educational Grants Davis Phinney Foundation $15,000.00 Educational Grants Dermatologic Society of $100,000.00 Corporate Sponsorships Greater New York Dermatology Education $50,000.00 Corporate Sponsorships Foundation Dermatology Foundation $135,000.00 Charitable Donations Dermatology Foundation $50,000.00 Corporate Sponsorships Dermatology Nurses $18,000.00 Corporate Sponsorships Associate Dermatology PA Foundation $2,700.00 Corporate Sponsorships Digestive Disease Week $32,400.00 Corporate Sponsorships Digestive Disease Week $80,000.00 Corporate Sponsorships Digestive Disease Week $255,300.00 Corporate Sponsorships Digestive Health Foundation $50,000.00 Corporate Sponsorships Direct Relief $25,000.00 Charitable Donations Direct Relief $10,000,000.00 Charitable Donations Direct Relief $25,000,000.00 Charitable Donations Direct Relief $5,000,000.00 Charitable Donations Direct Relief $10,000,000.00 Charitable Donations Doctor Solomon Carter $10,000.00 Educational Grants Fuller Mental Health Center Doctor Solomon Carter $50,000.00 Educational Grants Fuller Mental Health Center Drew University Health $2,500.00 Educational Grants Services Drexel Unviersity $55,000.00 Fellowships and Scholarships Drugs for Neglected $10,000.00 Charitable Donations Diseases Initiative North America Inc. East Tennessee Foundation $1,500.00 Corporate Sponsorships Ecog Research and Education $20,000.00 Educational Grants Foundation Inc. Ecog Research and Education $20,000.00 Educational Grants Foundation Inc. Economic Alliance for $5,000.00 Corporate Sponsorships Michigan Eisenhower Desert ($30,000.00) Educational Grants Orthopedic Center Eisenhower Desert $75,000.00 Educational Grants Orthopedic Center Eisenhower Desert $300,000.00 Educational Grants Orthopedic Center Eisenhower Desert $95,000.00 Educational Grants Orthopedic Center Eisenhower Desert $90,000.00 Educational Grants Orthopedic Center Eisenhower Desert $563,360.00 Educational Grants Orthopedic Center Eisenhower Desert $50,000.00 Educational Grants Orthopedic Center Eisenhower Desert $35,100.00 Educational Grants Orthopedic Center Eisenhower Desert $250,000.00 Educational Grants Orthopedic Center Eisenhower Desert $475,000.00 Educational Grants Orthopedic Center Eisenhower Desert $50,000.00 Educational Grants Orthopedic Center Embarcadero Lions Club of $2,500.00 Corporate Sponsorships Sacramento Employers Health Coalition $5,000.00 Corporate Sponsorships Endocrine Education Inc. $25,000.00 Educational Grants Endocrine Society $25,000.00 Educational Grants Endocrine Society $25,000.00 Educational Grants Endocrine Society ($10,928.00) Educational Grants Endocrine Society $20,000.00 Educational Grants Endometriosis Associate $50,000.00 Charitable Donations Endometriosis Foundation of $30,000.00 Corporate Sponsorships America Enzyme Mechanism Conference $2,500.00 Educational Grants Epilepsy Association of $7,500.00 Corporate Sponsorships Central Florida Epilepsy Foundation $15,000.00 Corporate Sponsorships Epilepsy Foundation of $5,000.00 Corporate Sponsorships Florida Epilepsy Foundation of $10,000.00 Corporate Sponsorships Michigan Ethiopian Community $2,000.00 Corporate Sponsorships Association of Greater Philadelphia Excellence in $100,000.00 Corporate Sponsorships Gastroenterology Education LLC Excellence in $110,000.00 Corporate Sponsorships Gastroenterology Education LLC Excellence in Rheumatology $100,000.00 Corporate Sponsorships Education LLC Family Reach Foundation $5,000,000.00 Charitable Donations Federation of American $2,000.00 Educational Grants Society for Experimental Biology Faseb Federation of American $2,000.00 Educational Grants Society for Experimental Biology Faseb Federation of American $2,000.00 Educational Grants Society for Experimental Biology Faseb Federation of American $2,000.00 Educational Grants Society for Experimental Biology Faseb Federation of Clinical $20,000.00 Educational Grants Immunology Society Federation of Clinical $20,000.00 Educational Grants Immunology Society Federation of Clinical $12,500.00 Educational Grants Immunology Society Federation of Clinical $20,000.00 Fellowships and Immunology Society Scholarships Feed My Starving Children $500.00 Charitable Donations Feinstein Institute for Med $243,900.00 Educational Grants Research Fibroid Foundation $90,000.00 Charitable Donations Fibroid Foundation $95,000.00 Charitable Donations Florida Academy of Family $18,000.00 Corporate Sponsorships Physicians Florida Atlantic University $1,000.00 Charitable Donations Foundation Inc. Florida Coalition $10,000.00 Corporate Sponsorships Florida Gastroenterological $7,500.00 Corporate Sponsorships Society Florida Society of $70,000.00 Corporate Sponsorships Dermatology Physician Assistants Inc. Florida Society of $50,000.00 Corporate Sponsorships Rheumatology Inc. Florida Society of $5,000.00 Corporate Sponsorships Rheumatology Inc. Focus Med Communications $35,000.00 Corporate Sponsorships Focus Med Communications $135,000.00 Corporate Sponsorships Footsteps for Fertility $1,000.00 Corporate Sponsorships Foundation Force--Facing Our Risk of $5,000.00 Charitable Donations Cancer Emp Forsyth Area Striders Team $500.00 Corporate Sponsorships Foundation Fighting $2,500.00 Corporate Sponsorships Blindness Foundation for Biomedical $50,000.00 Charitable Donations Research Foundation for The National $5,000.00 Corporate Sponsorships Institute of Health Foundation of Consortium of $17,500.00 Fellowships and Multiple Sclerosis Centers Scholarships Cmsc Foundation of Consortium of $40,000.00 Educational Grants Multiple Sclerosis Centers Cmsc Foundation of Consortium of $32,875.00 Patient Support Multiple Sclerosis Centers Cmsc Franklin and Marshall $1,000.00 Charitable Donations College French American Chemical $3,000.00 Educational Grants Society Friends of Cancer Research $25,000.00 Charitable Donations Friends of Cancer Research $25,000.00 Corporate Sponsorships Friends of Cancer Research $25,000.00 Corporate Sponsorships Friends of The St Louis $50,000.00 Corporate Sponsorships Univ Liver Center Fundacion Puertorriquena DE $17,960.00 Educational Grants Pacientes Consult Endometriosis Gastrointestinal and Liver $150,000.00 Corporate Sponsorships Association of The Americas Inc. Gastrointestinal Health $90,000.00 Corporate Sponsorships Foundation Inc. Gateway for Cancer Research $10,000.00 Charitable Donations Genesis Healthcare $3,000.00 Corporate Sponsorships Foundation George Washington Univ $3,000.00 Corporate Sponsorships Georgia Academy of Family $3,500.00 Corporate Sponsorships Physicians Georgia Dermatology $50,000.00 Corporate Sponsorships Physican Assistants Georgia Society of $7,500.00 Corporate Sponsorships Dermatology and Dermatologic Surgery Georgia Society of $75,000.00 Corporate Sponsorships Dermatology and Dermatologic Surgery Gildas Club Chicago $10,000.00 Charitable Donations Global Academy for Medical $20,000.00 Corporate Sponsorships Education Global Academy for Medical $43,750.00 Corporate Sponsorships Education Global Academy for Medical $40,500.00 Corporate Sponsorships Education Global Academy for Medical $76,500.00 Corporate Sponsorships Education Global Academy for Medical $58,500.00 Corporate Sponsorships Education Global Academy for Medical $76,500.00 Corporate Sponsorships Education Global Healthy Living $45,000.00 Corporate Sponsorships Foundation Global Healthy Living $75,000.00 Corporate Sponsorships Foundation Global Oncology $5,000.00 Corporate Sponsorships Good Grief $500.00 Corporate Sponsorships Gordon Research Conferences $2,500.00 Educational Grants Gordon Research Conferences $3,000.00 Educational Grants Gordon Research Conferences $1,000.00 Educational Grants Gordon Research Conferences $2,500.00 Educational Grants Gordon Research Conferences $3,000.00 Educational Grants Gordon Research Conferences $1,500.00 Educational Grants Gordon Research Conferences $2,000.00 Educational Grants Gordon Research Conferences $2,500.00 Educational Grants Gordon Research Conferences $2,000.00 Educational Grants Gordon Research Conferences $2,000.00 Educational Grants Gordon Research Conferences $2,000.00 Educational Grants Gordon Research Conferences $2,000.00 Educational Grants Gordon Research Conferences $1,000.00 Educational Grants Gordon Research Conferences $2,500.00 Educational Grants Grand Traverse Area $1,500.00 Corporate Sponsorships Parkinsons Support Group Gynecologic Oncology Group $10,000.00 Educational Grants Gynecologic Oncology Group $25,000.00 Educational Grants Gynecologic Oncology Group $5,500.00 Educational Grants Gynecologic Oncology Group $40,000.00 Educational Grants H Lee Moffitt Cancer Center $7,500.00 Educational Grants and Research Institute Halo House Foundation $10,000.00 Corporate Sponsorships Hamil Kerr Challenge $500.00 Corporate Sponsorships Harborside Press $30,400.00 Corporate Sponsorships Harborside Press $80,000.00 Corporate Sponsorships Hartford Hospital $5,000.00 Corporate Sponsorships Healthcare 21 Business $1,500.00 Corporate Sponsorships Coalition Healthwell Foundation $220,000.00 Charitable Donations Healthy Women $30,000.00 Corporate Sponsorships Heart To Heart $15,000.00 Charitable Donations International Inc. Heart To Heart $1,000.00 Charitable Donations International Inc. Heart To Heart $5,000.00 Charitable Donations International Inc. Henry M Jackson Foundation $10,000.00 Educational Grants Hepatitis C Association $20,000.00 Educational Grants Hepatitis C Mentor and $20,000.00 Patient Support Support Group The Hepatitis Education Project $25,000.00 Corporate Sponsorships Hermanas Carmelitas Teresas $393.79 Charitable Donations DE San Jose, Inc. Hidradenitis Suppurativa $10,000.00 Charitable Donations Foundation HIV Treaters Med Associate $7,500.00 Corporate Sponsorships of Puerto Rico HMP Communications $15,000.00 Corporate Sponsorships HMP Communications $70,000.00 Corporate Sponsorships Hope Foundation $25,000.00 Educational Grants Hospital of the University $10,000.00 Educational Grants of Pennsylvania Hospital of the University $75,000.00 Educational Grants of Pennsylvania Hospital of the University $5,000.00 Educational Grants of Pennsylvania Hospital of the University $10,000.00 Educational Grants of Pennsylvania Howard Hanna Children's $10,000.00 Charitable Donations Free Care Fund Hubbard Street Dance $10,000.00 Educational Grants Chicago Human Growth Foundation $5,000.00 Corporate Sponsorships Human Growth Foundation $2,000.00 Corporate Sponsorships Hunt for A Cure $1,250.00 Corporate Sponsorships Huntsman Cancer Foundation $500.00 Corporate Sponsorships Huntsman Cancer Foundation $2,000.00 Corporate Sponsorships Huntsman Cancer Foundation $2,500.00 Corporate Sponsorships IASLC Foundation $50,000.00 Fellowships and Scholarships IBD Horizons $2,500.00 Corporate Sponsorships IBD Horizons $2,500.00 Corporate Sponsorships IBD Horizons $50,000.00 Corporate Sponsorships Illinois Academy of Family $4,500.00 Educational Grants Physicians Illinois Cancercare $2,500.00 Corporate Sponsorships Foundation Illinois Society of $65,000.00 Corporate Sponsorships Dermatology Physician Assistants Imedex LLC $75,000.00 Educational Grants Imedex LLC ($1,119.00) Educational Grants Imedex LLC $25,000.00 Educational Grants Imedex LLC $30,000.00 Educational Grants Imedex LLC ($991.00) Educational Grants Imedex LLC $40,000.00 Educational Grants Imedex LLC $75,000.00 Educational Grants Imedex LLC $40,000.00 Educational Grants Imedex LLC $114,000.00 Corporate Sponsorships Imerman Angels $1,500.00 Charitable Donations Immune Deficiency $9,900.00 Corporate Sponsorships Foundation Impact Education LLC $75,000.00 Educational Grants Impact Education LLC $95,000.00 Educational Grants Improve Care Now Inc. $12,500.00 Corporate Sponsorships Improve Care Now Inc. $100,000.00 Patient Support Improve Care Now Inc. $12,500.00 Corporate Sponsorships Improve Care Now Inc. $12,500.00 Corporate Sponsorships Improve Care Now Inc. $12,500.00 Corporate Sponsorships Indian Doc Associate of $5,000.00 Corporate Sponsorships Houston Indiana Parkinson $4,250.00 Corporate Sponsorships Foundation Indy Hematology Education $30,000.00 Corporate Sponsorships Inc. Indy Hematology Education $19,000.00 Corporate Sponsorships Inc. Infectious Disease of $10,000.00 Patient Support Puerto Rico Innovation Foundation Inc. $55,000.00 Corporate Sponsorships Institute for Medical and $15,000.00 Educational Grants Nursing Education Integrated Med Foundation $15,000.00 Charitable Donations Integrated Med Foundation $9,500.00 Corporate Sponsorships Intellisphere LLC $7,000.00 Corporate Sponsorships Intellisphere LLC $15,500.00 Corporate Sponsorships Intellisphere LLC $10,500.00 Corporate Sponsorships Intellisphere LLC $16,000.00 Corporate Sponsorships Intellisphere LLC $18,500.00 Corporate Sponsorships Intellisphere LLC $12,500.00 Corporate Sponsorships Internaltional Society for $17,500.00 Corporate Sponsorships Pharmacoeconomics and Outcomes Research International Association $311,000.00 Corporate Sponsorships for The Study of Lung Cancer International Association $15,000.00 Corporate Sponsorships for The Study of Lung Cancer International Association $75,000.00 Corporate Sponsorships for The Study of Lung Cancer International Biometric $3,875.00 Corporate Sponsorships Society Eastern North American Region International Dermatology $70,000.00 Corporate Sponsorships Outcome Measures International Dermatology $70,000.00 Corporate Sponsorships Outcome Measures International Medical Corps $5,000.00 Charitable Donations International Meyoloma $100,000.00 Corporate Sponsorships Foundation International Meyoloma $15,000.00 Corporate Sponsorships Foundation International Meyoloma $25,000.00 Charitable Donations Foundation International Meyoloma $10,000.00 Educational Grants Foundation International Myeloma $50,000.00 Corporate Sponsorships Society (IMS) International Organization $50,000.00 Patient Support of Multiple Sclerosis Nurses International Pelvic Pain $23,000.00 Corporate Sponsorships Society International Pelvic Pain $5,000.00 Corporate Sponsorships Society International Physician $75,000.00 Corporate Sponsorships Ntwrk Dba International Oncology Ntwrk International Physician $95,000.00 Corporate Sponsorships Ntwrk Dba International Oncology Ntwrk International Physician $75,000.00 Corporate Sponsorships Ntwrk Dba International Oncology Ntwrk International Psoriasis $25,000.00 Corporate Sponsorships Council International Psoriasis $50,000.00 Corporate Sponsorships Council International Society for $5,000.00 Educational Grants Antiviral Research It Takes Guts $1,000.00 Corporate Sponsorships Johns Hopkins Technology $50,000.00 Educational Grants Ventures Johns Hopkins Technology $20,000.00 Educational Grants Ventures Johns Hopkins Technology $40,000.00 Fellowships and Ventures Scholarships Johns Hopkins Technology $2,500.00 Corporate Sponsorships Ventures Johns Hopkins Technology $75,000.00 Educational Grants Ventures Johns Hopkins Technology $25,000.00 Educational Grants Ventures Johns Hopkins Technology $40,000.00 Fellowships and Ventures Scholarships Johns Hopkins Technology $40,000.00 Fellowships and Ventures Scholarships Johns Hopkins Technology $40,000.00 Fellowships and Ventures Scholarships Johns Hopkins Technology $70,000.00 Corporate Sponsorships Ventures Johns Hopkins Technology $50,000.00 Fellowships and Ventures Scholarships Johns Hopkins Technology $10,000.00 Educational Grants Ventures Johns Hopkins University ($3,916.11) Educational Grants Johns Hopkins University ($2,784.14) Educational Grants JWC Covenant Inc. $50,000.00 Educational Grants Kansas Univ Endowment $40,000.00 Educational Grants Association Kelsey Research Foundation $40,000.00 Fellowships and Scholarships Kentucky Rural Health $35,000.00 Corporate Sponsorships Association Kentucky Rural Health $25,000.00 Corporate Sponsorships Association Kentucky Rural Health $5,000.00 Corporate Sponsorships Association Laboratorio Clinico Toledo $900.00 Patient Support Laboratorio Clinico Toledo $1,095.00 Patient Support Laboratorio Clinico Toledo $900.00 Patient Support Laboratorio Clinico Toledo $2,250.00 Patient Support Laboratorio Clinico Toledo $5,325.00 Patient Support Laboratorio Clinico Toledo $465.00 Patient Support Laboratorio Clinico Toledo $1,500.00 Patient Support Laboratorio Clinico Toledo $750.00 Patient Support Laboratorio Clinico Toledo $1,500.00 Patient Support Laboratorio Clinico Toledo $315.00 Patient Support Laboratorio Clinico Toledo $705.00 Patient Support Laboratorio Clinico Toledo $2,295.00 Patient Support Laboratorio Clinico Toledo $348.00 Patient Support Laboratorio Clinico Toledo $435.00 Patient Support Laboratorio Clinico Toledo $750.00 Patient Support Laboratorio Clinico Toledo $1,050.00 Patient Support Laboratorio Clinico Toledo $372.00 Patient Support Laboratorio Clinico Toledo $255.00 Patient Support Laboratorio Clinico Toledo $600.00 Patient Support Laboratorio Clinico Toledo $600.00 Patient Support Laboratorio Clinico Toledo $825.00 Patient Support Laboratorio Clinico Toledo $345.00 Patient Support Laboratorio Clinico Toledo $600.00 Patient Support Laboratorio Clinico Toledo $750.00 Patient Support Laboratorio Clinico Toledo $1,200.00 Patient Support Laboratorio Clinico Toledo $1,500.00 Patient Support Laboratorio Clinico Toledo $1,125.00 Patient Support Laboratorio Clinico Toledo $255.00 Patient Support Laboratorio Clinico Toledo $480.00 Patient Support Laboratorio Clinico Toledo $750.00 Patient Support Laboratorio Clinico Toledo $1,500.00 Patient Support Laboratorio Clinico Toledo $705.00 Patient Support Laboratorio Clinico Toledo $885.00 Patient Support Laboratorio Clinico Toledo $1,695.00 Patient Support Laboratorio Clinico Toledo $480.00 Patient Support Laboratorio Clinico Toledo $525.00 Patient Support Laboratorio Clinico Toledo $915.00 Patient Support Laboratorio Clinico Toledo $1,200.00 Patient Support Laboratorio Clinico Toledo $600.00 Patient Support Laboratorio Clinico Toledo $675.00 Patient Support Laboratorio Clinico Toledo $1,200.00 Patient Support Laboratorio Clinico Toledo $3,000.00 Patient Support Laboratorio Clinico Toledo $900.00 Patient Support Laboratorio Clinico Toledo $360.00 Patient Support Laboratorio Clinico Toledo $1,290.00 Patient Support Laboratorio Clinico Toledo $900.00 Patient Support Laboratorio Clinico Toledo $1,200.00 Patient Support Laboratorio Clinico Toledo $750.00 Patient Support Laboratorio Clinico Toledo $1,500.00 Patient Support Laboratorio Clinico Toledo $1,500.00 Patient Support Laboratorio Clinico Toledo $930.00 Patient Support Laboratorio Clinico Toledo $1,200.00 Patient Support Laboratorio Clinico Toledo $675.00 Patient Support Laboratorio Clinico Toledo $600.00 Patient Support Laboratorio Clinico Toledo $750.00 Patient Support Laboratorio Clinico Toledo $525.00 Patient Support Laboratorio Clinico Toledo $750.00 Patient Support Laboratorio Clinico Toledo $360.00 Patient Support Laboratorio Clinico Toledo $1,680.00 Patient Support Laboratorio Clinico Toledo $525.00 Patient Support Laboratorio Clinico Toledo $600.00 Patient Support Laboratorio Clinico Toledo $375.00 Patient Support Laboratorio Clinico Toledo $990.00 Patient Support Laboratorio Clinico Toledo $1,830.00 Patient Support Laboratorio Clinico Toledo $600.00 Patient Support Laboratorio Clinico Toledo $600.00 Patient Support Lahey Hospital and Medical $3,000.00 Corporate Sponsorships Center Lake County Crisis Center $5,000.00 Charitable Donations Lake County Haven $10,000.00 Charitable Donations Large Urology Group $66,400.00 Corporate Sponsorships Practice Associate Large Urology Group $20,000.00 Corporate Sponsorships Practice Associate Large Urology Group $20,000.00 Corporate Sponsorships Practice Associate Large Urology Group $5,000.00 Corporate Sponsorships Practice Associate Leukemia and Lymphoma $50,000.00 Patient Support Society Inc. Leukemia and Lymphoma $5,000.00 Corporate Sponsorships Society Inc. Leukemia and Lymphoma $5,000.00 Corporate Sponsorships Society Inc. Leukemia and Lymphoma $100,000.00 Corporate Sponsorships Society Inc. Leukemia and Lymphoma $100,000.00 Educational Grants Society Inc. Leukemia and Lymphoma $2,000.00 Corporate Sponsorships Society Inc. Leukemia and Lymphoma $5,000.00 Corporate Sponsorships Society Inc. Leukemia and Lymphoma $95,000.00 Corporate Sponsorships Society Inc. Leukemia and Lymphoma $70,000.00 Corporate Sponsorships Society Inc. Leukemia and Lymphoma $50,000.00 Educational Grants Society Inc. Leukemia and Lymphoma $50,000.00 Educational Grants Society Inc. Leukemia and Lymphoma $3,500.00 Corporate Sponsorships Society Inc. Leukemia Research $50,000.00 Fellowships and Foundation Inc. Scholarships Leukemia Research $10,000.00 Corporate Sponsorships Foundation Inc. Leukemia Research $5,000.00 Charitable Donations Foundation Inc. Leukemia Research $5,000.00 Educational Grants Foundation Inc. Leukemia Research $50,000.00 Fellowships and Foundation Inc. Scholarships Linkage To Health Inc. $25,000.00 Educational Grants Liver Health Connection $40,000.00 Educational Grants Liver Health Connection $5,000.00 Corporate Sponsorships Livestrong Foundation $10,000.00 Charitable Donations Loma Linda University $10,000.00 Educational Grants School of Medicine Lung Cancer Alliance $25,000.00 Corporate Sponsorships Lung Cancer Research $25,000.00 Charitable Donations Foundation Lung Cancer Research $20,000.00 Corporate Sponsorships Foundation Lungevity Foundation $5,000.00 Corporate Sponsorships Lungevity Foundation $25,000.00 Charitable Donations Lungevity Foundation $10,000.00 Corporate Sponsorships Lungevity Foundation $10,000.00 Educational Grants Lupus and Allied Diseases $15,000.00 Corporate Sponsorships Association, Inc. Lymphoma Research $10,000.00 Corporate Sponsorships Foundation Lymphoma Research $25,000.00 Corporate Sponsorships Foundation Lymphoma Research $40,000.00 Corporate Sponsorships Foundation Lymphoma Research $10,000.00 Corporate Sponsorships Foundation Lymphoma Research $15,000.00 Corporate Sponsorships Foundation Lymphoma Research $25,000.00 Corporate Sponsorships Foundation Lymphoma Research $50,000.00 Corporate Sponsorships Foundation Magellan Rx Management Inc. $10,000.00 Corporate Sponsorships March of Dimes Foundation $5,000.00 Corporate Sponsorships Massachusetts General $30,000.00 Educational Grants Hospital Massachusetts General $40,000.00 Fellowships and Hospital Scholarships Massachusetts Society for $10,000.00 Charitable Donations Med Research Mayo Clinic $7,500.00 Corporate Sponsorships Mayo Clinic Scottsdale $8,000.00 Educational Grants Pharmacy Mayo Clinic Scottsdale $10,000.00 Educational Grants Pharmacy Mckesson Specialty Health $60,000.00 Corporate Sponsorships Pharmaceuticals and Biotechnology Solutions Mckesson Specialty Health $25,000.00 Corporate Sponsorships Pharmaceuticals and Biotechnology Solutions Mckesson Specialty Health $65,000.00 Corporate Sponsorships Pharmaceuticals and Biotechnology Solutions ME Strong Inc. $5,000.00 Corporate Sponsorships Med--LQ LLC $75,000.00 Educational Grants Med--LQ LLC $75,000.00 Educational Grants Med--LQ LLC $75,000.00 Educational Grants Med Conference Planners $7,500.00 Corporate Sponsorships Med Educator Consortium $10,000.00 Corporate Sponsorships Med Univ of South Carolina $2,500.00 Educational Grants Foundation Medical Education Resources $20,000.00 Corporate Sponsorships Medical Learning Institute $148,000.00 Educational Grants Medical Learning Institute $95,000.00 Educational Grants Medical Learning Institute $55,495.00 Educational Grants Medical Learning Institute $50,000.00 Educational Grants Medical Learning Institute ($715.00) Educational Grants Medical Oncology $20,000.00 Corporate Sponsorships Association of Southern California Medical Univ of South $1,250.00 Corporate Sponsorships Carolina Medical Univ of South $1,250.00 Corporate Sponsorships Carolina Medical Univ of South $7,500.00 Corporate Sponsorships Carolina Medicinal and Bioorganic $5,000.00 Educational Grants Chemistry Foundation The Medina Community Clinic $1,000.00 Corporate Sponsorships Medscape LLC ($7,703.00) Educational Grants Medscape LLC ($2,475.00) Educational Grants Medscape LLC ($205.88) Educational Grants Medstar Georgetown $800.00 Corporate Sponsorships Transplant Institute Fairfax Medstar Health Inc. $10,000.00 Educational Grants Meeting Designs LLC $20,000.00 Corporate Sponsorships Memorial Hermann Foundation $1,500.00 Corporate Sponsorships Memorial Hermann Foundation $5,000.00 Corporate Sponsorships Memorial Sloan Kettering $25,000.00 Educational Grants Cancer Center Merriam LLC Dba World Class $73,085.00 Educational Grants Cme Metavivor Research and $4,000.00 Charitable Donations Support, Inc. Methodist Dallas Med Center $5,000.00 Corporate Sponsorships Irb Methodist Hospital $25,000.00 Corporate Sponsorships Metropolitan Chicago Breast $5,000.00 Charitable Donations Cancer Michael J Fox Foundation $10,000.00 Corporate Sponsorships Michael J Fox Foundation $1,000.00 Corporate Sponsorships Michael J Fox Foundation $600,000.00 Corporate Sponsorships Michael J Fox Foundation $25,000.00 Corporate Sponsorships Michael J Fox Foundation $25,000.00 Corporate Sponsorships Michigan Parkinson $5,000.00 Corporate Sponsorships Foundation Michigan Parkinson $3,000.00 Corporate Sponsorships Foundation Michigan Rheumatism Society $25,000.00 Corporate Sponsorships Midwest Business Group On $3,000.00 Corporate Sponsorships Health Midwest Parkinsons $1,000.00 Corporate Sponsorships Initiative Miles for Cystic Fibrosis $2,500.00 Corporate Sponsorships Miles for Cystic Fibrosis $15,000.00 Charitable Donations Minnesota Urological $5,000.00 Corporate Sponsorships Society Mississippi Arthritis and $10,000.00 Corporate Sponsorships Rheumatism Society Missouri Hepatitis C $25,000.00 Educational Grants Alliance MIT Medical Obstetrics and $10,000.00 Charitable Donations Gynecology Montana Academy of $1,500.00 Corporate Sponsorships Ophthalmology Montefiore Med Center $40,000.00 Fellowships and Scholarships Mount Sinai School of $2,500.00 Educational Grants Medicine Mount Sinai School of $30,000.00 Corporate Sponsorships Medicine Mount Sinai School of $10,000.00 Educational Grants Medicine Mount Sinai School of $40,000.00 Educational Grants Medicine Mountain Area Center $1,200.00 Corporate Sponsorships Education Center Movement Disorder Society $2,500.00 Educational Grants Movement Disorder Society $10,000.00 Educational Grants Movement Disorder Society $25,000.00 Corporate Sponsorships Movement Disorder Society $25,000.00 Corporate Sponsorships Movement Disorder Society $15,000.00 Corporate Sponsorships Movement Disorder Society $208,750.00 Corporate Sponsorships Movement Disorder Society $50,000.00 Corporate Sponsorships Multiple Myeloma Research $25,000.00 Patient Support Foundation Inc. Multiple Myeloma Research $50,000.00 Patient Support Foundation Inc. Multiple Myeloma Research $10,000.00 Patient Support Foundation Inc. Multiple Myeloma Research $20,000.00 Patient Support Foundation Inc. Multiple Myeloma Research $25,000.00 Corporate Sponsorships Foundation Inc. Multiple Myeloma Research $55,000.00 Fellowships and Foundation Inc. Scholarships Multiple Myeloma Research $20,000.00 Educational Grants Foundation Inc. Multiple Myeloma Research $20,000.00 Educational Grants Foundation Inc. Multiple Myeloma Research $75,000.00 Educational Grants Foundation Inc. Multiple Myeloma Research $50,000.00 Educational Grants Foundation Inc. Multiple Myeloma Research $75,000.00 Educational Grants Foundation Inc. Musella Foundation for $10,000.00 Corporate Sponsorships Brain Tumor Research and Information Inc. Nami Oregon $2,250.00 Corporate Sponsorships Nami Oregon $2,250.00 Corporate Sponsorships Nami Tennessee $2,500.00 Corporate Sponsorships National Academy of $30,000.00 Corporate Sponsorships Dermatology Nurse Practitioners National Academy of Science $85,000.00 Corporate Sponsorships National AIDS Treatment $300,000.00 Charitable Donations Advocacy Project (NATAP) National Alliance of $20,000.00 Corporate Sponsorships Healthcare Purchaser Coalitions National Alliance of State $100,000.00 Corporate Sponsorships and Territorial Aids Directors National Alliance of State $50,000.00 Charitable Donations and Territorial Aids Directors National Animal Interest $15,000.00 Charitable Donations Alliance National Associate of $45,000.00 Educational Grants Managed Care Physician National Associate of $20,000.00 Educational Grants Managed Care Physician National Associate of $45,000.00 Educational Grants Managed Care Physician National Association of $300.00 Charitable Donations Area Agencies On Aging (N4a) National Association of $6,600.00 Corporate Sponsorships Community Health Centers Nachc National Association of $10,000.00 Charitable Donations School Nurses Inc. National Brain Tumor $5,700.00 Charitable Donations Society Inc. National Brain Tumor $25,000.00 Corporate Sponsorships Society Inc. National Brain Tumor $50,000.00 Charitable Donations Society Inc. National Brain Tumor $50,000.00 Educational Grants Society Inc. National Brain Tumor $50,000.00 Corporate Sponsorships Society Inc. National Coalition for $50,000.00 Corporate Sponsorships Cancer Survivorship National Coalition for $2,500.00 Corporate Sponsorships Cancer Survivorship National Coalition for $2,500.00 Corporate Sponsorships Cancer Survivorship National Coalition for $25,000.00 Corporate Sponsorships Cancer Survivorship National Coalition for $25,000.00 Corporate Sponsorships Cancer Survivorship National Community $80,000.00 Corporate Sponsorships Dispensing Associate Ncoda National Comprehensive $15,000.00 Corporate Sponsorships Cancer Network National Comprehensive $15,000.00 Corporate Sponsorships Cancer Network National Comprehensive $40,000.00 Corporate Sponsorships Cancer Network National Comprehensive $30,000.00 Educational Grants Cancer Network National Comprehensive $60,000.00 Educational Grants Cancer Network National Comprehensive $75,000.00 Educational Grants Cancer Network National Comprehensive $5,000.00 Corporate Sponsorships Cancer Network National Comprehensive $25,000.00 Educational Grants Cancer Network National Comprehensive $50,000.00 Educational Grants Cancer Network National Comprehensive $55,000.00 Educational Grants Cancer Network National Comprehensive $40,000.00 Patient Support Cancer Network Foundation National Comprehensive $100,000.00 Fellowships and Cancer Network Foundation Scholarships National Comprehensive $40,000.00 Patient Support Cancer Network Foundation National Comprehensive $25,000.00 Patient Support Cancer Network Foundation National Comprehensive $40,000.00 Patient Support Cancer Network Foundation National Comprehensive $50,000.00 Charitable Donations Cancer Network Foundation National Comprehensive $100,000.00 Fellowships and Cancer Network Foundation Scholarships National Eczema Association $10,000.00 Corporate Sponsorships National Health Council $50,000.00 Corporate Sponsorships National Minority Quality $75,000.00 Corporate Sponsorships forum Inc. National Minority Quality $75,000.00 Corporate Sponsorships forum Inc. National Multiple Sclerosis $10,000.00 Corporate Sponsorships Society National Pancreas $150,000.00 Educational Grants Foundation National Pancreas $75,000.00 Corporate Sponsorships Foundation National Pancreas $75,000.00 Charitable Donations Foundation National Pancreas $70,000.00 Corporate Sponsorships Foundation National Partnership for $5,000.00 Corporate Sponsorships Women and Families Inc. National Psoriasis $50,000.00 Fellowships and Foundation Scholarships National Psoriasis $15,000.00 Corporate Sponsorships Foundation National Psoriasis $25,000.00 Corporate Sponsorships Foundation National Psoriasis $50,000.00 Corporate Sponsorships Foundation National Psoriasis $5,000.00 Corporate Sponsorships Foundation National Psoriasis $50,000.00 Educational Grants Foundation National Psoriasis $35,000.00 Corporate Sponsorships Foundation National Psoriasis $25,000.00 Educational Grants Foundation National Psoriasis $150,000.00 Corporate Sponsorships Foundation National Psoriasis $30,000.00 Corporate Sponsorships Foundation National Psoriasis $15,000.00 Corporate Sponsorships Foundation National Psoriasis $50,000.00 Corporate Sponsorships Foundation National Psoriasis $75,000.00 Fellowships and Foundation Scholarships National Psoriasis $30,000.00 Corporate Sponsorships Foundation National Psoriasis $40,000.00 Corporate Sponsorships Foundation National Psoriasis $40,000.00 Corporate Sponsorships Foundation National Society for $55,000.00 Corporate Sponsorships Cutaneous Medicine National Society for $80,000.00 Corporate Sponsorships Cutaneous Medicine National Society for $225,000.00 Corporate Sponsorships Cutaneous Medicine National Society for $160,000.00 Corporate Sponsorships Cutaneous Medicine New England Immunology $2,500.00 Corporate Sponsorships Conference Inc. New Jersey Academy of ($7,440.00) Educational Grants Family Physicians New York Academy of Science $3,500.00 Educational Grants New York Academy of Science $5,000.00 Educational Grants New York Academy of Science $5,000.00 Educational Grants New York Academy of Science $2,500.00 Educational Grants New York Cancer Foundation $10,000.00 Corporate Sponsorships New York University School ($5,000.00) Educational Grants of Medicine Nikki Mitchell Foundation $7,500.00 Corporate Sponsorships NL Communications Inc. $35,000.00 Educational Grants NL Communications Inc. $75,000.00 Educational Grants NL Communications Inc. $25,000.00 Educational Grants NL Communications Inc. $225,000.00 Educational Grants NL Communications Inc. $25,000.00 Educational Grants NL Communications Inc. $55,000.00 Educational Grants NL Communications Inc. $30,000.00 Educational Grants NL Communications Inc. $85,000.00 Educational Grants NL Communications Inc. $35,000.00 Educational Grants NL Communications Inc. $25,000.00 Educational Grants NL Communications Inc. $75,000.00 Educational Grants NL Communications Inc. $45,000.00 Educational Grants NL Communications Inc. $75,000.00 Educational Grants NL Communications Inc. $20,000.00 Educational Grants NL Communications Inc. $30,000.00 Educational Grants NL Communications Inc. $50,000.00 Educational Grants NL Communications Inc. $25,000.00 Educational Grants NL Communications Inc. $60,000.00 Educational Grants NL Communications Inc. $125,000.00 Educational Grants NL Communications Inc. $145,000.00 Educational Grants North American Center for $375,000.00 Educational Grants Continuing Med Education North American Society for $5,000.00 Corporate Sponsorships Pediatric and Adolescent Gynecology North American Society for $25,000.00 Educational Grants Pediatric Gastroenterology Hepatology and Nutrition North Carolina Academy of $235,500.00 Educational Grants Family Physcians North Carolina Academy of $10,000.00 Corporate Sponsorships Family Physcians North Carolina Oncology $5,000.00 Corporate Sponsorships Management Society North Carolina Society of $5,000.00 Corporate Sponsorships Eye Physicians and Surgeons North Dakota Pharmacists $2,500.00 Corporate Sponsorships Association Northeast Business Group On $10,000.00 Corporate Sponsorships Health Northeast Business Group On $7,500.00 Corporate Sponsorships Health Northeast Kidney Foundation $5,000.00 Corporate Sponsorships Inc. Northern California Society $20,000.00 Corporate Sponsorships for Clinical Gastroenterology Northwell Health $10,000.00 Corporate Sponsorships Northwest Parkinsons $5,000.00 Patient Support Foundation Northwest Parkinsons $5,000.00 Patient Support Foundation Northwestern Univ $50,000.00 Fellowships and Scholarships Northwestern Univ $5,000.00 Corporate Sponsorships Northwestern Univ $5,000.00 Educational Grants Northwestern Univ $3,000.00 Educational Grants Northwestern Univ $3,000.00 Fellowships and Scholarships Northwestern Univ $10,000.00 Corporate Sponsorships Nutrition4kids, LLC $75,000.00 Patient Support Nutrition4kids, LLC $100,000.00 Patient Support NYU School of Medicine $7,500.00 Educational Grants NYU School of Medicine $40,000.00 Fellowships and Scholarships NYU School of Medicine $10,000.00 Educational Grants Cardiothoracic Surgery NYU School of Medicine $7,500.00 Educational Grants Cardiothoracic Surgery Ochsner Clinic Foundation $10,000.00 Corporate Sponsorships Ocular Immunology and $65,000.00 Corporate Sponsorships Uveitis Foundation Ohio Association of $1,300.00 Corporate Sponsorships Community Health Centers Ohio Association of $10,000.00 Corporate Sponsorships Rheumatology Ohio Gastroenterology $5,000.00 Corporate Sponsorships Society Ohio Gastroenterology $3,000.00 Corporate Sponsorships Society Ohio State Univ $3,500.00 Educational Grants Omnia Education Inc. $231,475.00 Educational Grants Oncology Nursing Society $38,500.00 Corporate Sponsorships Oncology Nursing Society $9,100.00 Corporate Sponsorships Oregon Health and Science $3,000.00 Patient Support Univ Oregon Health and Science $12,000.00 Corporate Sponsorships Univ Oregon Health and Science $10,000.00 Educational Grants Univ Our Brain Bank $50,000.00 Corporate Sponsorships Pacific Business Group On $15,000.00 Corporate Sponsorships Health Pacific Business Group On $6,250.00 Corporate Sponsorships Health Pacific Business Group On $6,250.00 Corporate Sponsorships Health Pacific Business Group On $6,250.00 Corporate Sponsorships Health Pacific Business Group On $6,250.00 Corporate Sponsorships Health Pacific Dermatologic $20,000.00 Corporate Sponsorships Association Pacific Dermatologic $30,000.00 Corporate Sponsorships Association Pack Center LLC $242,750.00 Patient Support Pack Center LLC $200,000.00 Patient Support Pack Center LLC $13,100.00 Educational Grants Pack Center LLC $125,500.00 Educational Grants Pack Center LLC $110,225.00 Educational Grants Pack Center LLC $151,700.00 Educational Grants Pancreatic Cancer Action $50,000.00 Educational Grants Network Para LA Naturaleza Inc. $500.00 Charitable Donations Park Nicollet Foundation $1,000.00 Corporate Sponsorships Park Nicollet Foundation $1,000.00 Corporate Sponsorships Parkinson Alliance $1,000.00 Corporate Sponsorships Parkinson and Movement $10,000.00 Patient Support Disorder Alliance Parkinson and Movement $15,000.00 Patient Support Disorder Alliance Parkinson and Movement $50,000.00 Patient Support Disorder Alliance Parkinson and Movement $100,000.00 Corporate Sponsorships Disorder Alliance Parkinson and Movement $15,000.00 Patient Support Disorder Alliance Parkinson and Movement $10,000.00 Educational Grants Disorder Alliance Parkinson Association of $1,000.00 Corporate Sponsorships Alabama Parkinson Association of $1,250.00 Corporate Sponsorships Greater Daytona Beach Pagdb Parkinson Association of $1,000.00 Corporate Sponsorships Northern California Parkinson Association of $1,000.00 Corporate Sponsorships The Carolinas Parkinson Association of $1,000.00 Corporate Sponsorships The Carolinas Parkinson Council $25,000.00 Corporate Sponsorships Parkinson Foundation of $1,000.00 Corporate Sponsorships Oklahoma Parkinson Foundation of The $10,000.00 Patient Support National Capital Area Parkinson Foundation of The $10,000.00 Patient Support National Capital Area Parkinson Foundation of The $2,500.00 Corporate Sponsorships National Capital Area Parkinson Foundation $5,000.00 Corporate Sponsorships Western Pennsylvania Parkinson Ntwrk of Arizona $500.00 Corporate Sponsorships Parkinson Support Center of $10,000.00 Corporate Sponsorships Kentuciana Parkinson Support Center of $2,500.00 Corporate Sponsorships Kentuciana Parkinson's Association of $1,000.00 Corporate Sponsorships San Diego Parkinson's Association of $17,000.00 Corporate Sponsorships San Diego Parkinsons Association of $7,500.00 Patient Support The Rockies Parkinsons Awareness $1,250.00 Corporate Sponsorships Association of Central Indiana Parkinsons Disease $2,500.00 Corporate Sponsorships Foundation Parkinsons Disease $5,000.00 Corporate Sponsorships Foundation Parkinsons Disease $25,000.00 Corporate Sponsorships Foundation Parkinsons Disease $5,000.00 Corporate Sponsorships Foundation Parkinsons Disease $135,000.00 Corporate Sponsorships Foundation Parkinsons Disease $2,500.00 Corporate Sponsorships Foundation Parkinsons Disease $10,000.00 Corporate Sponsorships Foundation Parkinsons Disease $4,500.00 Corporate Sponsorships Foundation Parkinson's Nebraska $1,000.00 Corporate Sponsorships Parkinson's Nebraska $1,000.00 Corporate Sponsorships Parkinsons Unity Walk $54,000.00 Corporate Sponsorships Partnership for A Drug Free $75,000.00 Charitable Donations America Partnership for Cures $60,000.00 Patient Support Partnership for Quality Med $1,000.00 Charitable Donations Donations Pqmd Partnership for Quality Med $5,000.00 Charitable Donations Donations Pqmd Patient Access Network $1,200,000.00 Charitable Donations Foundation Patient Access Network $12,007,000.00 Charitable Donations Foundation Patient Access Network $5,000,000.00 Charitable Donations Foundation Patient Access Network $10,000,000.00 Charitable Donations Foundation Patient Access Network $11,200,000.00 Charitable Donations Foundation Patient Access Network $11,022,000.00 Charitable Donations Foundation Patient Access Network $30,000,000.00 Charitable Donations Foundation Patient Empowerment Ntwrk $20,000.00 Patient Support Patient Empowerment Ntwrk $40,000.00 Patient Support Patient Empowerment Ntwrk $10,000.00 Patient Support Patient Empowerment Ntwrk $10,000.00 Patient Support Patient Empowerment Ntwrk $20,000.00 Patient Support Patient Empowerment Ntwrk $20,000.00 Patient Support Patient Empowerment Ntwrk $30,000.00 Patient Support Patient Empowerment Ntwrk $10,000.00 Charitable Donations Patient Empowerment Ntwrk $20,000.00 Patient Support PD Gladiators $10,000.00 Corporate Sponsorships PD Gladiators $10,000.00 Charitable Donations Pediatric Specialists of $2,500.00 Corporate Sponsorships Virginia LLC Peerview Institute for $5,000.00 Educational Grants Medical Education Pennsylvania Academy of $10,000.00 Corporate Sponsorships Dermatology and Dermatologic Surgry Pennsylvania Prostate $1,000.00 Corporate Sponsorships Cancer Coalition Pennsylvania Society of $10,000.00 Corporate Sponsorships Gastroenterology Pennsylvania Society of $5,000.00 Corporate Sponsorships Gastroenterology People To People Health $15,000.00 Charitable Donations Foundation People To People Health $20,000.00 Charitable Donations Foundation Pharmacy Benefit Management $7,500.00 Corporate Sponsorships Institute Pharmacy Benefit Management $5,500.00 Corporate Sponsorships Institute Phoenix Obgyn Society $2,000.00 Corporate Sponsorships Phoenix Rheumatology $10,000.00 Corporate Sponsorships Association Phrmct Care Management $95,000.00 Corporate Sponsorships Associate Physicians Continuing $42,000.00 Corporate Sponsorships Education Physicians Education $42,550.00 Educational Grants Resource LLC Physicians Education $50,000.00 Educational Grants Resource LLC Physicians Education $85,000.00 Educational Grants Resource LLC Physicians Education $100,000.00 Educational Grants Resource LLC Physicians Education $40,000.00 Educational Grants Resource LLC Physicians Education $50,000.00 Educational Grants Resource LLC Physicians Education $75,000.00 Educational Grants Resource LLC Pinnacle Clinical Research $5,000.00 Corporate Sponsorships Pins for Parkinsons $500.00 Corporate Sponsorships Platformq Health Education, $125,000.00 Educational Grants LLC Postgraduate Healthcare $25,000.00 Educational Grants Education LLC Postgraduate Institute for $50,000.00 Educational Grants Medicine Postgraduate Institute for $350,000.00 Educational Grants Medicine Presbyterian Healthcare $5,000.00 Corporate Sponsorships Foundation President and Fellows of $12,000.00 Educational Grants Harvard College President and Fellows of $20,000.00 Corporate Sponsorships Harvard College President and Fellows of $30,000.00 Educational Grants Harvard College President and Fellows of $11,500.00 Educational Grants Harvard College President and Fellows of $3,000.00 Educational Grants Harvard College President and Fellows of ($18,400.00) Educational Grants Harvard College Prevent Cancer Foundation $25,000.00 Corporate Sponsorships Prevent Cancer Foundation $100,000.00 Corporate Sponsorships Prime Education Inc. $120,000.00 Educational Grants Prime Education Inc. $225,000.00 Educational Grants Prime Education Inc. $150,000.00 Educational Grants Prime Education Inc. $199,725.00 Educational Grants Prime Education Inc. $200,000.00 Educational Grants Prime Education Inc. $200,000.00 Educational Grants Prime Education Inc. $295,217.00 Educational Grants Prime Education Inc. $93,930.00 Educational Grants Prime Education Inc. $200,000.00 Educational Grants Prime Education Inc. $274,830.00 Educational Grants Prime Education Inc. $200,000.00 Educational Grants Prime Education Inc. $200,000.00 Educational Grants Prime Oncology Inc. $150,000.00 Educational Grants Prime Oncology Inc. $85,000.00 Educational Grants Prime Oncology Inc. $81,260.00 Educational Grants Prime Oncology Inc. $86,320.00 Educational Grants Prime Oncology Inc. $222,410.00 Educational Grants Prime Oncology Inc. $75,000.00 Educational Grants Prime Oncology Inc. $75,000.00 Educational Grants Prime Oncology LLC ($21,072.00) Educational Grants Primo Education LLC $15,000.00 Corporate Sponsorships Project Inform $50,000.00 Charitable Donations Project Inform $10,000.00 Corporate Sponsorships Projects in Knowledge Inc. $125,000.00 Educational Grants Projects in Knowledge Inc. $78,000.00 Educational Grants Promis Health Organization $10,000.00 Educational Grants Prostate Cancer Foundation $1,400.00 Corporate Sponsorships Chicago Prostate Cancer $5,000.00 Charitable Donations International Prostate Cancer Research $15,000.00 Corporate Sponsorships Instutute Prostaware $1,500.00 Corporate Sponsorships Prostaware $1,500.00 Corporate Sponsorships Providence Health and $20,000.00 Patient Support Services Southern California Psoriasis and Psoriatic $100,000.00 Corporate Sponsorships Arthritis Clinics Multicenter Advancement Network Puerto Rico Associate of ($1,088.60) Educational Grants Gastroenterology Puerto Rico Associate of $5,000.00 Corporate Sponsorships Gastroenterology Puerto Rico Associate of $30,000.00 Corporate Sponsorships Gastroenterology Puerto Rico Associate of $20,000.00 Educational Grants Gastroenterology Puerto Rico Nephrology $3,500.00 Corporate Sponsorships Society Inc. Puerto Rico Obstetrician $1,400.00 Corporate Sponsorships and Gyn Inc. Puerto Rico Obstetrician $17,000.00 Corporate Sponsorships and Gyn Inc. Puerto Rico Obstetrician $5,000.00 Corporate Sponsorships and Gyn Inc. Purdue Univ College of $50,000.00 Educational Grants Pharmacy Purdue Univ College of $200,000.00 Educational Grants Pharmacy Purdue Univ College of ($18,852.35) Educational Grants Pharmacy Purdue Univ College of $150,000.00 Educational Grants Pharmacy Randolph College $1,000.00 Charitable Donations Regents of The Univ of $5,000.00 Educational Grants California Regents of The Univ of $40,000.00 Fellowships and California Scholarships Regents of The Univ of $40,000.00 Fellowships and California Scholarships Regents of The Univ of $17,612.00 Fellowships and California Scholarships Regents of The Univ of $2,500.00 Patient Support California Regents of The Univ of $55,000.00 Fellowships and California Scholarships Regents of The Univ of $40,000.00 Fellowships and California Scholarships Regents of The Univ of $10,000.00 Educational Grants California Regents of The Univ of $25,000.00 Corporate Sponsorships California Regents of The Univ of $10,000.00 Educational Grants California Regents of The Univ of $20,000.00 Corporate Sponsorships Michigan Regents of The Univ of $1,000.00 Educational Grants Michigan Regents of The Univ of $1,000.00 Corporate Sponsorships Michigan Respiratory Health $4,050.00 Corporate Sponsorships Association of Metropolitan Chicago Respiratory Health $4,050.00 Corporate Sponsorships Association of Metropolitan Chicago Respiratory Health $4,050.00 Corporate Sponsorships Association of Metropolitan Chicago Revolutionizing Atopic $35,000.00 Corporate Sponsorships Dermatitis Rheumatology Association of $10,000.00 Corporate Sponsorships Minnesota and The Dakotas Rheumatology Nurses Society $87,500.00 Educational Grants Rheumlgy Alliance of $25,000.00 Corporate Sponsorships Louisiana Rheumnow $105,000.00 Corporate Sponsorships Rheumnow $60,000.00 Corporate Sponsorships Richmond County Medical $2,500.00 Corporate Sponsorships Society Riverside Medical Clinic $10,000.00 Patient Support Charitable Foundation Rocky Mountain MS Center $5,000.00 Patient Support Ronald Mcdonald House $60,000,000.00 Charitable Donations Charities, Inc. Ronald Mcdonald House $20,000,000.00 Charitable Donations Charities, Inc. Ronald Mcdonald House $20,000,000.00 Charitable Donations Charities, Inc. Roswell Park Alliance $5,000.00 Educational Grants Foundation Rotary Club of Downtown $1,000.00 Corporate Sponsorships Macon Runx1 Foundation $2,500.00 Educational Grants Rush University Medical $65,000.00 Educational Grants Center Rush University Medical $75,000.00 Educational Grants Center Rush University Medical $5,000.00 Charitable Donations Center Rush University Medical $300.00 Charitable Donations Center Rush University Medical $95,000.00 Educational Grants Center Rush University Medical $85,000.00 Educational Grants Center Rush University Medical $113,550.00 Educational Grants Center Rush University Medical $75,000.00 Educational Grants Center Safety Pharmacology Society $5,000.00 Educational Grants Samaritan Daytop Village $2,500.00 Corporate Sponsorships San Francisco Aids $10,000.00 Charitable Donations Foundation San Francisco Public Center $100,000.00 Charitable Donations Foundation San Francisco Retina $5,000.00 Educational Grants Foundation San Juan Bautista Medical $40,000.00 Fellowships and Center Scholarships Scripps Health $10,000.00 Corporate Sponsorships Scripps Health $66,500.00 Corporate Sponsorships Scripps Health $20,000.00 Educational Grants Seattle Science Foundation $8,500.00 Educational Grants Shanti $10,000.00 Charitable Donations Share $7,500.00 Charitable Donations Sociedad Dermatologica de $20,000.00 Corporate Sponsorships Puerto Rico Sociedad Dermatologica de $15,000.00 Corporate Sponsorships Puerto Rico Sociedad PR Endocrinologia $15,000.00 Corporate Sponsorships y Diabetologia Sociedad Puertorriquena $5,000.00 Corporate Sponsorships Pediatria Society for Clinical Trials $2,000.00 Corporate Sponsorships Society for Leukocyte $2,000.00 Educational Grants Biology Society for Neuro-Oncology $50,000.00 Corporate Sponsorships Society for Neuro-Oncology $20,000.00 Educational Grants Society for Neuro-Oncology $39,140.00 Educational Grants Society for Neuro-Oncology $58,000.00 Educational Grants Society for Neuro-Oncology $50,000.00 Corporate Sponsorships Society for Physician $10,000.00 Charitable Donations Assistants in Pediatrics Society for Womens Health $25,000.00 Corporate Sponsorships Research Society of Dermatology $50,000.00 Corporate Sponsorships Physician Assistants Society of Dermatology $40,000.00 Corporate Sponsorships Physician Assistants Society of Gynecologic $27,500.00 Corporate Sponsorships Surgeons Society of Investigative $30,000.00 Educational Grants Dermatology Socty for Gynecologic $10,000.00 Corporate Sponsorships Investigation Socty for Immunotherapy of $50,000.00 Corporate Sponsorships Cancer Socty for Immunotherapy of $5,000.00 Educational Grants Cancer Socty for Immunotherapy of $25,000.00 Corporate Sponsorships Cancer South Carolina Alliance of $6,000.00 Corporate Sponsorships Health Plans South Dakota Parkinson $2,500.00 Corporate Sponsorships Foundation South Dakota Parkinson $1,000.00 Corporate Sponsorships Foundation South Sound Care Foundation $3,250.00 Corporate Sponsorships Southern California Society $100,000.00 Corporate Sponsorships of Gastroenterology Spondylitis Association of $20,000.00 Patient Support America Spondylitis Association of $40,000.00 Patient Support America Spondylitis Association of $17,750.00 Educational Grants America Spondyloarthritis Research $70,000.00 Corporate Sponsorships and Treatment Network Spartan St. Barnabas Hospital $1,300.00 Fellowships and Scholarships St. Jude Childrens Research $30,000,000.00 Charitable Donations Hospital St. Jude Childrens Research $20,000,000.00 Charitable Donations Hospital St. Lukes Hospital $2,500.00 Corporate Sponsorships State of West Virginia $2,500.00 Corporate Sponsorships Rheumatology Society Super Jake Foundation The $25,000.00 Charitable Donations Susan G Komen Colorado $5,000.00 Corporate Sponsorships Susan G Komen Colorado $5,000.00 Corporate Sponsorships Talem Health Inc. $95,000.00 Educational Grants Talem Health Inc. $235,820.00 Educational Grants Tarsus Cardiology Inc. Dba $35,000.00 Corporate Sponsorships South Beach Symposium Texas Academy of Family $2,500.00 Corporate Sponsorships Physicians Texas Academy of Family $2,500.00 Corporate Sponsorships Physicians Foundation Texas Healthcare and $5,000.00 Corporate Sponsorships Bioscience Texas Indo-American $5,000.00 Corporate Sponsorships Physicians Society Texas Medical Association $5,000.00 Corporate Sponsorships Texas Osteopathic Medical $3,000.00 Corporate Sponsorships Association Foundation Thomas Jefferson University $5,000.00 Educational Grants Thomas Jefferson University $3,000.00 Corporate Sponsorships Thomas Jefferson University $3,000.00 Corporate Sponsorships Thomas Jefferson University $3,000.00 Corporate Sponsorships Thomas Jefferson University $5,000.00 Corporate Sponsorships Translational Research in $5,000.00 Educational Grants Oncology US Inc. Trinity International $1,000.00 Charitable Donations College Tufts Medical Center ($1,190.13) Educational Grants Tufts Medical Center ($513.14) Educational Grants UC Regents Maxillofacial $10,000.00 Educational Grants Prosthetics Clinic UC Regents Maxillofacial $40,000.00 Fellowships and Prosthetics Clinic Scholarships UC Regents Maxillofacial $15,000.00 Educational Grants Prosthetics Clinic Ultimate Medical Academy ($4,043.06) Educational Grants LLC Ultimate Medical Academy $174,700.00 Educational Grants LLC Ultimate Medical Academy $50,000.00 Educational Grants LLC Ultimate Medical Academy ($2,344.80) Educational Grants LLC Ultimate Medical Academy $150,000.00 Educational Grants LLC Ultimate Medical Academy $100,000.00 Educational Grants LLC Ultimate Medical Academy $125,000.00 Educational Grants LLC Ultimate Medical Academy ($5,138.86) Educational Grants LLC Ultimate Medical Academy ($3,284.05) Educational Grants LLC Ultimate Medical Academy ($2,134.44) Educational Grants LLC Ultimate Medical Academy ($9,000.00) Educational Grants LLC Ultimate Medical Academy ($885.32) Educational Grants LLC Ultimate Medical Academy $245,000.00 Educational Grants LLC Ultimate Medical Academy $95,000.00 Educational Grants LLC Ultimate Medical Academy $500,000.00 Educational Grants LLC Ultimate Medical Academy $349,450.00 Educational Grants LLC UMA Education Inc. Dba $50,000.00 Educational Grants Global Education Group UMA Education Inc. Dba $375,000.00 Educational Grants Global Education Group UMA Education Inc. Dba $225,000.00 Educational Grants Global Education Group UMA Education Inc. Dba $43,358.00 Educational Grants Global Education Group UMA Education Inc. Dba $163,000.00 Educational Grants Global Education Group UMA Education Inc. Dba $166,000.00 Educational Grants Global Education Group UMA Education Inc. Dba $10,000.00 Educational Grants Global Education Group UMASS Memorial Foundation $2,500.00 Corporate Sponsorships Inc. United Medical Center $2,280.00 Educational Grants United Rheumatology $225,000.00 Corporate Sponsorships United Spinal Association $12,500.00 Corporate Sponsorships Inc. United Spinal Association $12,500.00 Corporate Sponsorships Inc. United States Adult Cystic $5,000.00 Patient Support Fibrosis Association Inc. United States and Canadian $30,000.00 Corporate Sponsorships Academy of Pathology United States Renal Care $20,000.00 Corporate Sponsorships Inc. Unity Health Care, Inc. $7,500.00 Corporate Sponsorships Univ Connecticut ($2,054.94) Educational Grants Dermatology Univ Connecticut $40,000.00 Fellowships and Dermatology Scholarships Univ Health Service at $20,000.00 Educational Grants Stony Point Inc. Univ Health Service at $120,000.00 Corporate Sponsorships Stony Point Inc. Univ Health Service at $120,000.00 Corporate Sponsorships Stony Point Inc. Univ of Chicago $8,000.00 Educational Grants Univ of Chicago $50,000.00 Patient Support Univ of Chicago $10,000.00 Educational Grants Univ of Chicago $15,000.00 Educational Grants Univ of Chicago $25,000.00 Educational Grants Univ of Chicago ($2,097.00) Educational Grants Univ of Chicago $125,000.00 Educational Grants Univ of Chicago $5,000.00 Corporate Sponsorships Univ of Chicago $10,000.00 Corporate Sponsorships Univ of Chicago $5,000.00 Educational Grants Univ of Chicago $5,000.00 Corporate Sponsorships Univ of Chicago $20,000.00 Corporate Sponsorships Univ of Chicago $18,000.00 Educational Grants Univ of Chicago ($7,232.53) Educational Grants Univ of Chicago $1,000.00 Charitable Donations Univ of Chicago $10,000.00 Educational Grants Univ of Chicago $45,000.00 Educational Grants Univ of Chicago $10,000.00 Educational Grants Univ of Cincinnati ($68,461.18) Educational Grants Univ of Cincinnati $25,000.00 Corporate Sponsorships Univ of Cincinnati $60,000.00 Educational Grants Univ of Cincinnati $60,000.00 Educational Grants Univ of Cincinnati $75,000.00 Educational Grants Univ of Colorado Denver $20,000.00 Fellowships and School of Medicine Scholarships Univ of Connecticut Health $12,000.00 Fellowships and Center, John Dempsey Scholarships Hospital Univ of Florida Foundation $60,000.00 Fellowships and Scholarships Univ of Illinois Foundation $1,000.00 Charitable Donations Univ of Louisville $15,000.00 Corporate Sponsorships Univ of Louisville Research $60,000.00 Educational Grants Foundation Univ of Louisville Research $50,000.00 Educational Grants Foundation Univ of Louisville Research $60,000.00 Educational Grants Foundation Univ of Maryland Baltimore $10,000.00 Patient Support Foundation Inc. Univ of Maryland Baltimore $5,000.00 Educational Grants Foundation Inc. Univ of Massachusetts Med $2,500.00 Corporate Sponsorships School Univ of Miami $20,000.00 Corporate Sponsorships Univ of Miami $40,000.00 Fellowships and Scholarships Univ of Miami $10,000.00 Corporate Sponsorships Univ of Minnesota Regents $2,000.00 Educational Grants Univ of Nebraska Med Center $100,000.00 Corporate Sponsorships Univ of Nebraska Med Center $50,000.00 Educational Grants Univ of Nebraska Med Center $35,000.00 Educational Grants Univ of Nebraska Med Center $150,000.00 Educational Grants Univ of Nebraska Med Center $125,000.00 Educational Grants Univ of Nebraska Med Center $128,860.00 Educational Grants Univ of Nebraska Med Center $600.00 Corporate Sponsorships Univ of Nebraska Med Center $10,000.00 Corporate Sponsorships Univ of Nebraska Med Center $25,000.00 Corporate Sponsorships Univ of Nebraska Med Center $30,000.00 Educational Grants Univ of Nebraska Med Center $7,500.00 Educational Grants Univ of New Mexico Health $10,000.00 Educational Grants Science Center Dept of Pediatrics Neonatology Division Univ of Pittsburgh $15,000.00 Educational Grants Univ of Pittsburgh $2,200.00 Educational Grants Univ of Pittsburgh $20,000.00 Educational Grants Univ of South Florida Board $37,500.00 Fellowships and of Trustees Scholarships Univ of South Florida $25,000.00 Educational Grants Health Professions Conferencing Corp Univ of Southern California $1,500.00 Educational Grants Univ of Southern California $25,000.00 Educational Grants Univ of Southern California $7,097.77 Fellowships and Scholarships Univ of Southern California $81,500.00 Fellowships and Scholarships Univ of Texas at Austin $5,000.00 Educational Grants Univ of Texas Health $16,032.00 Corporate Sponsorships Science Center at San Antonio Univ of Texas Health $75,000.00 Educational Grants Science Center at San Antonio Univ of Toledo $2,000.00 Patient Support Univ of Utah $40,000.00 Fellowships and Scholarships Univ of Wisconsin--Madison $1,500.00 Educational Grants Univeristy of Chicago $15,000.00 Charitable Donations Cancer Research Foundation Universidad Central Del ($2,283.00) Educational Grants Caribe School of Medicine Universidad DE Puerto Rico $30,000.00 Fellowships and Scholarships Universidad DE Puerto Rico $59,783.50 Corporate Sponsorships Universidad DE Puerto Rico $30,000.00 Fellowships and Scholarships University Health Services $75,000.00 Educational Grants University Health Services $5,000.00 Educational Grants University Health Services $25,000.00 Educational Grants University of Alabama at $40,000.00 Fellowships and Birmingham Hospital Scholarships University of California $40,000.00 Fellowships and Irvine Scholarships University of California $6,000.00 Corporate Sponsorships San Francisco Foundation University of Illinois-- $15,821.60 Fellowships and Office of Business and Scholarships Financial Services University of Illinois-- $75,138.40 Fellowships and Office of Business and Scholarships Financial Services University of North $40,000.00 Fellowships and Carolina at Chapel Hill Scholarships University of North $1,000.00 Charitable Donations Carolina at Chapel Hill University of Rochester $5,000.00 Educational Grants University of South Florida ($9,615.55) Educational Grants Foundation University of Texas $55,000.00 Fellowships and Southwestern Medical Scholarships Center University of Texas $75,000.00 Fellowships and Southwestern Medical Scholarships Center University of Washington $40,000.00 Fellowships and Medical Center Scholarships University of Wisconsin LA $1,000.00 Charitable Donations Crosse Foundation Inc. Urogpo, LLC $35,000.00 Corporate Sponsorships Urological Association of $10,000.00 Corporate Sponsorships Physician Assistants Urology Center of Colorado $10,000.00 Corporate Sponsorships Foundation US Too International $1,500.00 Corporate Sponsorships US Too International $25,750.00 Corporate Sponsorships Vanderbilt Univ By and $190,000.00 Educational Grants Through Its Medical Center Vanderbilt Univ By and $10,000.00 Educational Grants Through Its Medical Center Vanderbilt Univ By and $5,000.00 Educational Grants Through Its Medical Center Vanderbilt Urology Society $3,000.00 Corporate Sponsorships Veritas Meeting Solutions $4,500.00 Corporate Sponsorships VHA Inc. $35,000.00 Corporate Sponsorships Vida Global Foundation $1,500.00 Corporate Sponsorships Vietnamese American $3,000.00 Corporate Sponsorships Healthcare Professionals Association of Georgia Vindico Med Education $50,000.00 Educational Grants Vindico Med Education $200,000.00 Educational Grants Vindico Med Education $50,000.00 Educational Grants Vindico Med Education $75,000.00 Educational Grants Vindico Med Education $50,000.00 Educational Grants Vindico Med Education $49,000.00 Educational Grants Vindico Med Education $50,000.00 Educational Grants Vindico Med Education $50,000.00 Educational Grants Virginia Academy of $1,750.00 Corporate Sponsorships Physician Assistants Virginia Commonwealth $7,500.00 Corporate Sponsorships University School of Medicine Virginia Council of Nurse $1,493.94 Corporate Sponsorships Practitioners Wake Forest Univ $40,000.00 Fellowships and Scholarships Wall Las Memorias $10,000.00 Corporate Sponsorships Wartburg College $1,000.00 Charitable Donations Washington International $2,500.00 Corporate Sponsorships Trade Foundation Washington International $2,500.00 Corporate Sponsorships Trade Foundation Washington International $2,500.00 Corporate Sponsorships Trade Foundation Washington International $2,500.00 Corporate Sponsorships Trade Foundation Washington Univ in St Louis ($263.21) Fellowships and Scholarships Washington Univ in St Louis $6,000.00 Educational Grants Washington Univ in St Louis $1,500.00 Corporate Sponsorships Washington Univ in St Louis $1,600.00 Fellowships and Scholarships Washington Univ in St Louis ($17,777.79) Educational Grants We Care in Inflammatory $25,000.00 Charitable Donations Bowel Disease WebMD Global LLC $90,000.00 Educational Grants WebMD Global LLC $209,983.00 Educational Grants WebMD Global LLC $209,983.00 Educational Grants WebMD Global LLC $209,983.00 Educational Grants WebMD Global LLC $50,000.00 Educational Grants WebMD Global LLC $63,500.00 Educational Grants WebMD Global LLC $81,500.00 Educational Grants WebMD Global LLC $95,000.00 Educational Grants WebMD Global LLC $348,000.00 Educational Grants WebMD Global LLC $151,000.00 Educational Grants WebMD Global LLC $172,000.00 Educational Grants WebMD Global LLC $200,000.00 Educational Grants WebMD Global LLC $75,000.00 Educational Grants WebMD Global LLC ($1,500.00) Educational Grants WebMD Global LLC ($1,142.14) Educational Grants WebMD Global LLC $100,000.00 Educational Grants WebMD Global LLC $65,000.00 Educational Grants WebMD Global LLC $182,500.00 Educational Grants WebMD Global LLC $150,000.00 Educational Grants WebMD Global LLC $75,000.00 Educational Grants WebMD Global LLC $350,000.00 Educational Grants WebMD Global LLC $100,000.00 Educational Grants WebMD Global LLC $113,500.00 Educational Grants WebMD Global LLC $200,000.00 Educational Grants WebMD Global LLC $227,000.00 Educational Grants WebMD Global LLC $150,000.00 Educational Grants WebMD Global LLC $350,000.00 Educational Grants WebMD Global LLC $120,000.00 Educational Grants WebMD Global LLC $136,150.00 Educational Grants WebMD Global LLC $215,000.00 Educational Grants WebMD Global LLC $319,770.00 Educational Grants West Virginia Community $5,000.00 Corporate Sponsorships Voices Wisconsin Collaborative for $3,750.00 Corporate Sponsorships Healthcare Quality Wisconsin Rheumatology $10,000.00 Corporate Sponsorships Association Wisconsin Rheumatology $10,000.00 Corporate Sponsorships Association Wisconsin Section American $2,000.00 Corporate Sponsorships Congress Obstetrics and Gynecologist Acog Women in Government $2,500.00 Corporate Sponsorships Foundation Ltd Women in Government $2,500.00 Corporate Sponsorships Foundation Ltd Women in Government $5,000.00 Corporate Sponsorships Foundation Ltd Women in Government $5,000.00 Corporate Sponsorships Foundation Ltd Women in Government $7,500.00 Corporate Sponsorships Foundation Ltd Women in Government $7,500.00 Corporate Sponsorships Foundation Ltd Women in Government $5,000.00 Corporate Sponsorships Foundation Ltd Women in Government $5,000.00 Corporate Sponsorships Foundation Ltd Women in Government $5,000.00 Corporate Sponsorships Foundation Ltd Women in Government $5,000.00 Corporate Sponsorships Foundation Ltd Women in Government $10,000.00 Corporate Sponsorships Foundation Ltd Women in Government $10,000.00 Corporate Sponsorships Foundation Ltd Women in Government $2,500.00 Corporate Sponsorships Foundation Ltd Women in Government $2,500.00 Corporate Sponsorships Foundation Ltd Women in Government $2,500.00 Corporate Sponsorships Foundation Ltd Women in Government $5,000.00 Corporate Sponsorships Foundation Ltd Women in Government $7,000.00 Corporate Sponsorships Foundation Ltd Women in Government $2,500.00 Corporate Sponsorships Foundation Ltd Women in Government $10,000.00 Corporate Sponsorships Foundation Ltd World Parkinson Coalition $50,000.00 Fellowships and Inc. Scholarships Worldwide Endomarch $5,000.00 Corporate Sponsorships Worldwide Endomarch $3,000.00 Corporate Sponsorships Yale Univ $5,000.00 Educational Grants Zebrafish Disease Models $5,000.00 Educational Grants Society Zero The Project To End $15,000.00 Corporate Sponsorships Prostate Cancer Zero The Project To End $270,000.00 Corporate Sponsorships Prostate Cancer Zero The Project To End $10,000.00 Corporate Sponsorships Prostate Cancer Zero The Project To End $12,000.00 Corporate Sponsorships Prostate Cancer Zero The Project To End $270,000.00 Corporate Sponsorships Prostate Cancer ------------------------------------------------------------------------ Exhibit 2 -------------------------------------------------------------------------------------------------------------------------------------------------------- Organization Legal Name 2014 2015 2016 2017 2018 -------------------------------------------------------------------------------------------------------------------------------------------------------- ALBERT B. SABIN VACCINE INSTITUTE, INC. 203,302.00 835,251.00 -------------------------------------------------------------------------------------------------------------------------------------------------------- ALS THERAPY DEVELOPMENT FOUNDATION INC. 5,159.91 -------------------------------------------------------------------------------------------------------------------------------------------------------- ALZHEIMER'S DISEASE AND RELATED DISORDERS ASSOCIATION, INC. 10,000.00 10,000.00 -------------------------------------------------------------------------------------------------------------------------------------------------------- AMERICAN CANCER SOCIETY, INC. 1,000.00 -------------------------------------------------------------------------------------------------------------------------------------------------------- AMERICAN RED CROSS 50,000.00 20,000.00 80,000.00 1,425,000.00 775,000.00 -------------------------------------------------------------------------------------------------------------------------------------------------------- AMERICARES FOUNDATION, INC. 100,000.00 50,000.00 25,000.00 250,000.00 400,000.00 -------------------------------------------------------------------------------------------------------------------------------------------------------- APNA GHAR, INC. (OUR HOME) 50,000.00 -------------------------------------------------------------------------------------------------------------------------------------------------------- ASIAN UNIVERSITY FOR WOMEN SUPPORT FOUNDATION 50,000.00 50,000.00 50,000.00 50,000.00 50,000.00 -------------------------------------------------------------------------------------------------------------------------------------------------------- ASTRAEA FOUNDATION, INC. 75,000.00 -------------------------------------------------------------------------------------------------------------------------------------------------------- BAYLOR COLLEGE OF MEDICINE INTERNATIONAL PEDIATRIC AIDS INITIATIVE 2,220,337.00 2,477,111.00 1,660,000.00 1,610,000.00 1,610,000.00 -------------------------------------------------------------------------------------------------------------------------------------------------------- BEACON PLACE NFP 100,000.00 100,000.00 125,000.00 150,000.00 -------------------------------------------------------------------------------------------------------------------------------------------------------- BERNARD P. FLORIANI FOUNDATION 50,000.00 75,000.00 110,000.00 420,000.00 -------------------------------------------------------------------------------------------------------------------------------------------------------- BIG BROTHERS BIG SISTERS OF METROPOLITAN CHICAGO 40,000.00 -------------------------------------------------------------------------------------------------------------------------------------------------------- BOYS AND GIRLS CLUB OF LAKE COUNTY 10,000.00 10,000.00 10,000.00 25,000.00 -------------------------------------------------------------------------------------------------------------------------------------------------------- CARING AMBASSADORS PROGRAM, INC. 253,282.00 -------------------------------------------------------------------------------------------------------------------------------------------------------- CASA LAKE COUNTY 25,000.00 25,000.00 25,000.00 25,000.00 -------------------------------------------------------------------------------------------------------------------------------------------------------- CATALYSIS LLC - -------------------------------------------------------------------------------------------------------------------------------------------------------- CENTER FOR NEIGHBORHOOD ENTERPRISE 50,000.00 -------------------------------------------------------------------------------------------------------------------------------------------------------- CENTRAIDE OF GREATER MONTREAL (Matching Grants--Canada) 11,000.00 11,000.00 19,600.00 -------------------------------------------------------------------------------------------------------------------------------------------------------- CHICAGO CARES INC. 314,504.00 18,000.00 15,000.00 -------------------------------------------------------------------------------------------------------------------------------------------------------- CHICAGO HORTICULTURAL SOCIETY 50,000.00 -------------------------------------------------------------------------------------------------------------------------------------------------------- CHICAGO HOUSE AND SOCIAL SERVICE AGENCY 25,000.00 -------------------------------------------------------------------------------------------------------------------------------------------------------- CHICAGO TOOLBANK 5,000.00 -------------------------------------------------------------------------------------------------------------------------------------------------------- CHINESE AMERICAN SERVICE LEAGUE 50,000.00 -------------------------------------------------------------------------------------------------------------------------------------------------------- CHOCOLATE CHIPS ASSOCIATION 10,000.00 -------------------------------------------------------------------------------------------------------------------------------------------------------- CITY OF NORTH CHICAGO 5,000.00 -------------------------------------------------------------------------------------------------------------------------------------------------------- COMMUNITY ACTION PARTNERSHIP OF LAKE COUNTY 150,400.00 141,875.00 -------------------------------------------------------------------------------------------------------------------------------------------------------- CRADLES TO CRAYONS, INC. 515,000.00 -------------------------------------------------------------------------------------------------------------------------------------------------------- CRISTO REY ST. MARTIN COLLEGE PREP 50,000.00 -------------------------------------------------------------------------------------------------------------------------------------------------------- DAVIS PHINNEY FOUNDATION 120.00 -------------------------------------------------------------------------------------------------------------------------------------------------------- IDIRECT RELIEF 1,865,000.00 1,941,111.00 1,325,000.00 2,115,000.00 850,000.00 -------------------------------------------------------------------------------------------------------------------------------------------------------- DRESS FOR SUCCESS WORLDWIDECENTRAL 90,000.00 -------------------------------------------------------------------------------------------------------------------------------------------------------- ERIE FAMILY HEALTH CENTER, INC. 100,000.00 55,000.00 50,000.00 50,000.00 50,000.00 -------------------------------------------------------------------------------------------------------------------------------------------------------- FAMILY REACH FOUNDATION 100,00.00 300,000.00 320,000.00 300,000.00 300,000.00 -------------------------------------------------------------------------------------------------------------------------------------------------------- FEEDING AMERICA 225,000.00 25,000.00 -------------------------------------------------------------------------------------------------------------------------------------------------------- FIELD MUSEUM OF NATURAL HISTORY 30,000.00 -------------------------------------------------------------------------------------------------------------------------------------------------------- FISHER HOUSE FOUNDATION, INC. 750,000.00 -------------------------------------------------------------------------------------------------------------------------------------------------------- FONDOS UNIDOS DE PUERTO RICO, INC. 136,400.00 -------------------------------------------------------------------------------------------------------------------------------------------------------- FOOD BANK OF EASTERN MICHIGAN 10,000.00 -------------------------------------------------------------------------------------------------------------------------------------------------------- GILDA'S CLUB CHICAGO 25,000.00 25,000.00 -------------------------------------------------------------------------------------------------------------------------------------------------------- GLOBAL HEALTH CORPS 50,000.00 100,000.00 100,000.00 100,000.00 100,000.00 -------------------------------------------------------------------------------------------------------------------------------------------------------- GLOBEMED NFP 50,000.00 75,000.00 75,000.00 75,000.00 75,000.00 -------------------------------------------------------------------------------------------------------------------------------------------------------- HABITAT FOR HUMANITY INTERNATIONAL 530,200.00 -------------------------------------------------------------------------------------------------------------------------------------------------------- HABITAT FOR HUMANITY, LAKE COUNTY IL, INC. 125,000.00 -------------------------------------------------------------------------------------------------------------------------------------------------------- HANDS ON ORLANDO, INC 150,000.00 -------------------------------------------------------------------------------------------------------------------------------------------------------- HEALTHREACH, INC. -------------------------------------------------------------------------------------------------------------------------------------------------------- HEART TO HEART INTERNATIONAL, INC. 35,000.00 535,000.00 310,000.00 -------------------------------------------------------------------------------------------------------------------------------------------------------- HISPANIC SCHOLARSHIP FUND 50,000.00 -------------------------------------------------------------------------------------------------------------------------------------------------------- ILLINOIS SCIENCE AND TECHNOLOGY INSTITUTE 70,000.00 40,000.00 80,000.00 -------------------------------------------------------------------------------------------------------------------------------------------------------- IMPACTING VETERANS LIVES, INC.--MIDWEST VETERANS CLOSET 50,000.00 -------------------------------------------------------------------------------------------------------------------------------------------------------- IMSA FUND FOR ADVANCEMENT OF EDUCATION 133,000.00 133,000.00 40,000.00 -------------------------------------------------------------------------------------------------------------------------------------------------------- INDIANA UNIVERSITY 1,150,000.00 1,100,000.00 1,100,000.00 1,100,000.00 1,100,000.00 -------------------------------------------------------------------------------------------------------------------------------------------------------- INTERNATIONAL MEDICAL CORPS 100,000.00 350,000.00 25,000.00 450,000.00 550,000.00 -------------------------------------------------------------------------------------------------------------------------------------------------------- JK GROUP, INC. (Matching Grants) -------------------------------------------------------------------------------------------------------------------------------------------------------- JUNIOR ACHIEVEMENT OF CHICAGO 33,500.00 50,000.00 50,000.00 -------------------------------------------------------------------------------------------------------------------------------------------------------- KABOOM! 342,582.00 397,081.00 -------------------------------------------------------------------------------------------------------------------------------------------------------- KIDS RANK 25,000.00 -------------------------------------------------------------------------------------------------------------------------------------------------------- KOHL CHILDREN'S MUSEUM 495,500.00 -------------------------------------------------------------------------------------------------------------------------------------------------------- KOHL CHILDREN'S MUSEUM OF GREATER CHICAGO 44,615.00 154,000.00 154,300.00 -------------------------------------------------------------------------------------------------------------------------------------------------------- LAKE COUNTY CARES 22,145.00 22,000.00 -------------------------------------------------------------------------------------------------------------------------------------------------------- LAKE COUNTY CRISIS CENTER FOR THE PREVENTION AND TREATMENT OF 10,000.00 10,000.00 10,000.00 25,000.00 DOMESTIC VIOLENCE, INC. -------------------------------------------------------------------------------------------------------------------------------------------------------- LAKE COUNTY VETERANS AND FAMILY SERVICES FOUNDATION 50,000.00 -------------------------------------------------------------------------------------------------------------------------------------------------------- MAP INTERNATIONAL 313,800.00 412,907.00 460,000.00 510,000.00 325,000.00 -------------------------------------------------------------------------------------------------------------------------------------------------------- MASSACHUSETTS BIOTECHNOLOGY EDUCATION FOUNDATION 40,000.00 -------------------------------------------------------------------------------------------------------------------------------------------------------- MEMORIAL SLOAN KETTERING CANCER CENTER 100,000.00 100,000.00 100,000.00 100,000.00 100,000.00 -------------------------------------------------------------------------------------------------------------------------------------------------------- MIDWEST ATHLETES AGAINST CHILDHOOD CANCER, INC 865.00 -------------------------------------------------------------------------------------------------------------------------------------------------------- MOTHERS TRUST FOUNDATION 25,000.00 -------------------------------------------------------------------------------------------------------------------------------------------------------- NATIONAL AUDUBON SOCIETY, INC. 12 ,500.00 -------------------------------------------------------------------------------------------------------------------------------------------------------- NATIONAL INVENTORS HALL OF FAME, INC. 225,000.00 225,000.00 153,900.00 176,000.00 259,725.00 -------------------------------------------------------------------------------------------------------------------------------------------------------- NATIONAL MULTIPLE SCLEROSIS SOCIETY 350.00 -------------------------------------------------------------------------------------------------------------------------------------------------------- NICASA, NFP -------------------------------------------------------------------------------------------------------------------------------------------------------- NORTH CHICAGO COMMUNITY PARTNERS 246,833.00 237,889,00 642,500.00 730,000.00 750,000.00 -------------------------------------------------------------------------------------------------------------------------------------------------------- NORTH CHICAGO COMMUNITY UNIT SCHOOL DISTRICT 187 100,600.00 165,000.00 828,430.00 -------------------------------------------------------------------------------------------------------------------------------------------------------- NORTHERN ILLINOIS FOOD BANK 14,400.00 15,000.00 25,000.00 30,000.00 55,000.00 -------------------------------------------------------------------------------------------------------------------------------------------------------- PADS LAKE COUNTY, INC. 10,000.00 10,000.00 10,000.00 10,000.00 25,000.00 -------------------------------------------------------------------------------------------------------------------------------------------------------- PARTNERS IN HEALTH 100,000.00 300,000.00 383,335.00 688,925.00 -------------------------------------------------------------------------------------------------------------------------------------------------------- POINTS OF LIGHT FOUNDATION 545,800.00 708,000.00 954,000.00 -------------------------------------------------------------------------------------------------------------------------------------------------------- PRAIRIE STATE LEGAL SERVICES, INC. 25,000.00 25,000.00 25,000.00 25,000.00 -------------------------------------------------------------------------------------------------------------------------------------------------------- PROJECT HOPE--THE PEOPLE-TO-PEOPLE HEALTH FOUNDATION, INC. 250,000.00 100,000.00 -------------------------------------------------------------------------------------------------------------------------------------------------------- READING POWER, INC. 10,000.00 40,000.00 58,000.00 260,000.00 300,000.00 -------------------------------------------------------------------------------------------------------------------------------------------------------- ROSALIND FRANKLIN UNIVERSITY OF MEDICINE AND SCIENCE 10,000.00 65,120.00 -------------------------------------------------------------------------------------------------------------------------------------------------------- SHEDD AQUARIUM 50,000.00 50,000.00 -------------------------------------------------------------------------------------------------------------------------------------------------------- SIEMPRE UNIDOS 60,000.00 -------------------------------------------------------------------------------------------------------------------------------------------------------- SILICON VALLEY COMMUNITY FOUNDATION (Matching Grants) 2,763,823.52 3,059,133.44 504,232.72 -------------------------------------------------------------------------------------------------------------------------------------------------------- STRENGTHEN ORLANDO, INC. 6,515.00 -------------------------------------------------------------------------------------------------------------------------------------------------------- TAPROOT FOUNDATION 200,000.00 -------------------------------------------------------------------------------------------------------------------------------------------------------- TEAM RUBICON 375,000.00 -------------------------------------------------------------------------------------------------------------------------------------------------------- TEXAS CHILDREN'S HOSPITAL 50,000.00 -------------------------------------------------------------------------------------------------------------------------------------------------------- THE ALS ASSOCIATION GREATER CHICAGO CHAPTER 5,000.00 -------------------------------------------------------------------------------------------------------------------------------------------------------- THE FULLER CENTER FOR HOUSING HERO PROJECT LAKE COUNTY 60,000.00 -------------------------------------------------------------------------------------------------------------------------------------------------------- THE HEART OF AMERICA FOUNDATION 726,910.00 1,019,652.00 1,327,500.00 2,050,000.00 1,993,300.00 -------------------------------------------------------------------------------------------------------------------------------------------------------- THE SCRIPPS RESEARCH INSTITUTE 290,000.00 -------------------------------------------------------------------------------------------------------------------------------------------------------- TPA NETWORK INCORPORATED 2,285.00 -------------------------------------------------------------------------------------------------------------------------------------------------------- TRAVIS MANION FOUNDATION 100,000.00 -------------------------------------------------------------------------------------------------------------------------------------------------------- UNITED WAY OF CENTRAL MASSACHUSETTS 44,000.00 45,000.00 61,000.00 -------------------------------------------------------------------------------------------------------------------------------------------------------- UNITED WAY OF LAKE COUNTY 80,000.00 80,000.00 70,000.00 -------------------------------------------------------------------------------------------------------------------------------------------------------- UNIVERSTIY OF CHICAGO 1,000,000.00 1,000,000.00 1,000,000.00 1,000,000.00 1,000.000.00 -------------------------------------------------------------------------------------------------------------------------------------------------------- UNIVERSITY OF NOTRE DAME 50,000.00 -------------------------------------------------------------------------------------------------------------------------------------------------------- WARRIORS AND QUIET WATERS FOUNDATION, INC. 50,000.00 -------------------------------------------------------------------------------------------------------------------------------------------------------- WILLIAM MARSH RICE UNIVERSITY 94,300.00 -------------------------------------------------------------------------------------------------------------------------------------------------------- WOUNDED WARRIOR PROJECT 750,000.00 -------------------------------------------------------------------------------------------------------------------------------------------------------- WPS60 110,000.00 -------------------------------------------------------------------------------------------------------------------------------------------------------- YBLC, INC. 15,000.00 15,000.00 15,000.00 -------------------------------------------------------------------------------------------------------------------------------------------------------- YOUR CAUSE HOLDINGS, LLC (Matching Grants) 2,805,067.87 4,120,115.28 7,012,295.67 -------------------------------------------------------------------------------------------------------------------------------------------------------- 12,292,102.52 13,593,332.35 15,187,786.59 19,856.907.28 26,850,256.67 -------------------------------------------------------------------------------------------------------------------------------------------------------- Note: Matching Grants are listed by Organizations that manage the program and not by the ultimate re Prepared Statement of Hon. Chuck Grassley, a U.S. Senator From Iowa I want to welcome the witnesses and thank them for being here. The information they share will help inform the committee as it addresses the issue of high prescription drug prices. America has a problem with the high cost of prescription medicines. Whether it's about the EpiPen, insulin, or other prescriptions, in the thousands of letters I've received, Iowans have made clear that high drug prices are hurting them. I've heard about people skipping doses of their prescription drugs to make them last until the next paycheck. I'm not a doctor, but rationing one's medicine doesn't sound like a safe prescription for health and wellness. Others have told me about leaving their prescription on the pharmacy counter because it cost too much. There is no question that researchers and doctors have developed treatments and cures for diseases where there were once none. And, such innovations take time and money. But, we're all trying to understand the sticker shock that many drugs generate. Especially when some of those drugs have been around for a long time. There is a balance between incentivizing innovation and keeping prices affordable for consumers and taxpayers. Like all systems, things can get out of balance. The good news is, we are here to discuss solutions. In fact, we are here today thanks to our system of checks and balances. Congress has a constitutional responsibility to be a meaningful check on the spending of taxpayer money. That responsibility includes not just holding hearings, but also holding the private sector and the government accountable through oversight. Just like a doctor has to properly diagnose a disease before it can be treated, Congress needs to understand what's going on in the drug pricing supply chain in order to respond in a measured and effective way. As a part of that fact-finding, as of last Friday, Ranking Member Wyden and I launched an inquiry into the high cost of insulin. This hearing is not about scapegoating any one group regarding high drug costs. That's why we're holding a series of bipartisan hearings on the issue. Without a doubt, drug pricing is a complex issue. But I think we should all be asking: Should it be so complex? We cannot allow anyone to hide behind the current complexities to shield the true cost of a drug. And, we shouldn't turn a blind eye to industry practices that thwart the laws and regulations designed to promote competition and generic drug entry in the market. Health and Human Services Secretary Alex Azar, FDA Commissioner Scott Gottlieb and the Federal Trade Commission have identified a number of tactics that undermine competition--like withholding samples, pay for delay, product-hopping, and rebate bundling, just to name a few. While these agencies are taking enforcement action or looking at regulatory changes, we here in Congress are exploring legislative options to deter companies from engaging in these practices that keep drug prices high for patients. Today, we expect open, honest answers from the pharmaceutical industry to figure out how we got here and see what ideas they have to make things better. One of the first things we need to talk about is list price. Secretary Azar has said that pharmaceutical companies believe that the list price is meaningless. In fact, some of your testimony today will echo that. However, for a patient taking a drug that has no competition, the list price is meaningful. For seniors on Part D who are paying co-insurance as a percentage of list price, the list price is meaningful. For people who have high deductible plans and pay thousands of dollars towards list price, the list price is meaningful. For pharmacy benefit managers, providing drugs with a high list price can be more attractive than providing a less expensive drug. Therefore, for taxpayers, the list price is meaningful. We've all seen the finger pointing. Every link in the supply chain has gotten skilled at that. But, like most Americans, I'm sick and tired of the blame game. It's time for solutions. One way or another, we're going to get some clarity. The American people deserve straight answers and real solutions. On that note, I want to remind each of you that it's a crime under title 18, U.S. Code, section 1001 to provide false testimony to Congress. Thank you for coming. I look forward to your testimony. ______ Prepared Statement of Pascal Soriot, Chief Executive Officer, AstraZeneca i. overview AstraZeneca appreciates the opportunity to engage with the committee on the important topic of drug pricing in the United States. We would like to emphasize our commitment to addressing these challenges and the important issues raised by the committee regarding drug pricing and affordability. AstraZeneca is a global, science-led biopharmaceutical company that focuses on the discovery, development and commercialization of prescription medicines, primarily for the treatment of diseases in three main therapy areas: Oncology; Cardiovascular; Renal and Metabolism; and Respiratory. We are also selectively active in the areas of autoimmunity, neuroscience, and infection. We are proud to call Wilmington, DE home to our North American headquarters. We are equally proud that one of our three global Research and Development (``R&D'') headquarters is located in Gaithersburg, MD. We are honored to contribute to improving the lives of millions of patients in the U.S. and across the globe. This statement is focused on four points explaining AstraZeneca's purpose, core values, and vision for the future: First, we are a science-led organization, as reflected in our continued investment in R&D and our success in introducing new treatments. Continuing to develop treatments that deliver long-term benefits to patients and the overall health of the U.S. population requires society's commitment to supporting investment in innovation through purchasing our medicines for the duration of patent protection at a responsible price that allows for the recoupment of the investment and risk associated with innovation. Second, we believe medicines are part of the solution to controlling health-care costs. They not only improve patient outcomes and increase quality of life, but also reduce downstream costs by keeping people healthy and out of the hospital. This contribution to reducing overall health-care costs should be considered when discussing drug pricing. Third, we recognize that we are only able to improve the lives of patients if they are able to take our medicines as prescribed. To that end, we are committed to sustaining and improving patient access and affordability. Fourth, we recognize that the current state of drug pricing in the U.S. health-care system is not sustainable and that patients are facing increasingly high out-of-pocket costs. We believe that these issues must be addressed urgently, and we hope to be a constructive partner in finding solutions. ii. benefits of innovation and r&d funding Science is at the core of what we do, and we are focused on being at the forefront of scientific innovation to deliver tomorrow's treatments and cures. Since 2017, the Food and Drug Administration (``FDA'') has approved 18 AstraZeneca products or significant indications, and five of our products have received breakthrough therapy designation. Breakthrough therapy designation is designed specifically for the expedited development and review of drugs for serious or life-threatening conditions, and these designations highlight how critical our work is to patient health in the U.S. For example, our oncology medicine CALQUENCE was granted breakthrough therapy designation for certain patients with mantle cell lymphoma and tezepelumab received such a designation for certain patients with severe asthma. In order to achieve these results, we reinvest a significant percentage of our revenues in research to identify the next generation of life-changing medicines. Over the past several years, we have worked tirelessly to rebuild our R&D pipeline. We now have approximately 8,900 employees in our R&D organization working at sites across the world. Our financial commitment to R&D has been significant. In 2018 alone, we spent nearly $6 billion on R&D, or 28 percent of our total product sales--a commitment to R&D that well exceeds the average spending of our research-based peers.\1\ Over the past six years, even as our revenues declined, we continued to make substantial investments in both R&D and acquiring products for our pipeline. In 2018, these investments have only just started to contribute to growth of our company. --------------------------------------------------------------------------- \1\ Pharmaceutical Research and Manufacturers of America (PhRMA). PhRMA Annual Membership Survey (2018). https://www.phrma.org/report/ 2018-phrma-annual-membership-survey. These results are possible only if society makes a commitment to support innovation so that treatments can be developed to the benefit --------------------------------------------------------------------------- of society as a whole for years to come. The development of new drug therapies requires society to make an up-front investment through purchasing our medicines during the patent protection period at a responsible price we charge, and then at a very substantially reduced price for an indefinite period after patent expiry when generics are introduced. Thus, long-term improvements in healthcare derived from new medicines can only be achieved if society is willing to pay a responsible price for a certain number of years that allows for the recoupment of the investment and risk involved in pharmaceutical innovation. Improvements in patient health and reduction of overall health-care costs over the long term are a direct result of this commitment to support innovation. For example, in the U.S., we have seen incredible progress in reducing cardiovascular disease morbidity and mortality. Between 2000 and 2014, age-adjusted mortality rates for cardiovascular and heart disease declined by approximately 35 percent; several factors have contributed to this decline, but the development of new medicines, including cholesterol-lowering medicines like statins, has played an important role.\2\ To take an AstraZeneca example, CRESTOR, a statin, was approved by the FDA in 2003. A study of CRESTOR showed that it reduced cardiovascular mortality and morbidity over the lifetime of the patient compared to the standard of care, resulting in economic value.\3\ --------------------------------------------------------------------------- \2\ Sidney S, Quesenberry CP, Jr, Jaffe MG, Sorel M, et al. Recent trends in cardiovascular mortality in the United States and public health goals. JAMA Cardiol. 2016;1(5):594-599. doi: 10.1001/ jamacardio.2016.1326. \3\ Ohsfeldt RL, Gandhi SK, Smolen LJ, et al. Cost effectiveness of rosuvastatin in patients at risk of cardiovascular disease based on findings from the JUPITER trial. J Med Econ. 2010;13(3):428-37. doi: 10.3111/13696998.2010.499758. It is important to note that there are significant risks involved in developing new therapies. Only approximately 12 percent of therapies entering clinical study are approved, and the average cost of development approaches $2.6 billion.\4\ In 2018, return on R&D investment among larger biopharmaceutical manufacturers fell to 1.9 percent, its lowest point since 2010.\5\ If we are not successful, we lose our investment in the therapy. Although we are proud of our success rate, we know that setbacks are inevitable when pushing the boundaries of science. For example, in 2018, we announced with our partner Lilly the discontinuation of Phase III clinical trials of lanabecestat, an investigational treatment for Alzheimer's disease. Such results are disappointing, but are an integral part of the nature of scientific discovery. --------------------------------------------------------------------------- \4\ DiMasi JA, Grabowski HG, Hansen RA. Innovation in the pharmaceutical industry: new estimates of R&D costs. J Health Econ. 2016;47:20-33. doi: 10.1016/j.jhealeco.2016.01.012. \5\ Deloitte Centre for Health Solutions. Unlocking R&D Productivity: Measuring the return from pharmaceutical innovation 2018. https://www2.deloitte.com/us/en/pages/life-sciences-and-health-care/ articles/measuring-return-from-pharmaceutical-innovation.html. Given the risks involved in developing a medicine, strong intellectual property (``IP'') protections and exclusivity for innovator products are a key component to ensuring that manufacturers continue to develop therapies that benefit society as a whole. While they create incentives to innovate, it is important to note that IP protections and exclusivity for innovator therapies do not generally prevent other competitor therapies from entering a given class, allowing robust competition to exist; for example, there are seven --------------------------------------------------------------------------- different statin molecules approved in the marketplace. Once these protections expire, generic and biosimilar competitors can enter the market, which further increases competition. Again, taking CRESTOR as example, since 2016 when it lost exclusivity, over 16 generic forms have been approved and are available in the market today, driving prices down very substantially. We strongly support this construct and policy efforts to encourage competition. We describe these proposals in section V of this statement. Finally, it is also worth noting that a significant portion of our R&D occurs here in the U.S. We invest more than $2.7 billion annually in U.S.-based R&D work, employing approximately 2,700 people in our science units within our R&D centers in Maryland, Massachusetts, and California. Our approach to R&D is consistent with our broader and long-standing commitment to U.S. jobs in research and manufacturing. Our largest footprint is in this country, with 12,800 employees throughout the U.S. Additionally, we recently completed a $200 million expansion in our Frederick, MD facility where biologics, including FASENRA for certain patients with severe asthma, and our immuno- oncology therapy, IMFINZI, are manufactured. This sustained investment in R&D leads to the creation of high-quality jobs and generates economic value in the U.S. To summarize, because we have put science and research at the center of our company, we have had more success in our R&D pipeline than ever before, delivering long-term healthcare benefits. This success, however, is only possible if society remains committed to supporting investment in innovation. iii. value of medicines The investments we make in researching and developing new therapies cannot occur in a vacuum. We must also ensure that our medicines bring value to patients, payers, and the health-care system as a whole. We are only able to stand behind the value of our medicines if that value is carefully and appropriately defined. In the health-care industry and as part of policymaking, there is frequent reflection on the meaning of ``value.'' We believe value must be assessed holistically and include all costs related to the treatment of a given condition. In particular, we must consider improvements in clinical outcomes and quality of life as well as reduction of hospitalizations and other medical costs. Additionally, the future savings that prescription medicines can bring to the healthcare system by preventing more costly interventions should not be overlooked as their value is considered. A recent study in Health Affairs of total Medicare spending per beneficiary from 1999 to 2012 found that the spending growth rate slowed to just 1.1 percent per year on average since 2005. The study found that half of the total slowdown was attributable to reduced spending growth on cardiovascular diseases and events, like heart attacks and related conditions. Increased medication use for conditions like hypertension, high cholesterol, and diabetes explained half of that effect. The authors noted that while large, even this impact of medications is likely to be understated.\6\ --------------------------------------------------------------------------- \6\ Cutler D, Ghosh K, et al., Explaining the Slowdown in Medical Spending Growth Among the Elderly, 1999-2012. Health Affairs. February 2019. doi: 10.1377/hlthaff.2018.05372. One of our own therapies--BRILINTA--is an example of a medicine used in the cardiovascular setting that brings value to both patients and the broader health-care system. This oral antiplatelet therapy is indicated to reduce the rate of cardiovascular death, heart attack, and stroke in patients with acute coronary syndrome (``ACS'') or a history of heart attacks. For at least the first 12 months following the diagnosis of ACS, BRILINTA has been shown to be superior to clopidogrel, a generic oral antiplatelet. In addition, in patients with ACS, BRILINTA in combination with aspirin resulted in 21 percent reduction in cardiovascular mortality compared to clopidogrel in combination with aspirin.\7\ --------------------------------------------------------------------------- \7\ Wallentin L, Becker RC, Budaj A, et al. Ticagrelor versus clopidogrel in patients with acute coronary syndromes. N Engl J Med. 2009;361(11):1045-57. doi: 10.1056/NEJMoa0904327. In addition, BRILINTA in combination with aspirin also resulted in lower medical care costs compared to clopidogrel in combination with aspirin. The lower medical costs are driven primarily by fewer hospital readmissions and cardiovascular revascularization interventions-- resulting in medical care cost offsets of approximately $1,000 per patient per year.\8\ This represents countless hours of patient time better spent with family and friends than in the hospital. --------------------------------------------------------------------------- \8\ Data on file. 2134602; AstraZeneca Pharmaceuticals LP. Another example of the value that medicines can provide relates to the relationship between diabetes and heart failure. In 2015, an estimated 30.2 million adults in the U.S. had diabetes, with the vast majority (90-95 percent) having type 2 diabetes.\9\ Up to 50 percent of patients with type 2 diabetes may develop heart failure.\10\ The prevalence of heart failure in the U.S. is expected to increase from 5.8 million in 2012 to 8.5 million in 2030.\11\ The total cost of heart failure, which includes direct and indirect costs, is projected to increase from $31 billion in 2012 to $70 billion in 2030, with the majority of these costs (80 percent) related to hospitalization.\12\ --------------------------------------------------------------------------- \9\ Centers for Disease Control and Prevention (CDC). National Diabetes Statistics Report, 2017. https://www.cdc.gov/diabetes/pdfs/ data/statistics/national-diabetes-statistics-report.pdf. \10\ American Diabetes Association. CV Disease and risk management: standards of medical care in diabetes--2019. Diabetes Care. 2019;42(Suppl 1);S103-S123. doi: 10.2337/dc19-S010. \11\ Heidenreich P, Albert N, Allen L, et al. Forecasting the impact of heart failure in the United States: a policy statement from the American Heart Association. Circ Heart Fail. 2013;6:606-619. doi: 10.1161/HHF.0b013e318291329a. \12\ Id. Our oral type 2 diabetes product FARXIGA is a sodium-glucose cotransporter 2 (SGLT2) inhibitor. This newest class of oral diabetes medication has consistently demonstrated cardiovascular benefits for diabetes patients that are absent in older diabetes treatments, further supporting the importance of biopharmaceutical innovation. A recent cardiovascular outcomes trial demonstrated that FARXIGA significantly reduced the risk for hospitalization for heart failure or cardiovascular death.\13\ With initial hospitalizations and readmissions for heart failure in the Medicare population exceeding $10,000 for each event in the U.S., it can be readily observed where these new therapies can help further reduce total cost of care in the most at-risk patient populations.\14\ --------------------------------------------------------------------------- \13\ Wiviott SD, Raz I, Bonaca MP, et al. for the DECLARE-TIMI 58 Investigators. Dapagliflozin and cardiovascular outcomes in type 2 diabetes [published online ahead of print November 10, 2018]. N Engl J Med. 2018. http://dx.doi.org/10.1056/NEJMoa1812389. Accessed November 10, 2018. \14\ Ziaeian B, Heidenreich PA, Xu H, et al. Medicare expenditures by race/ethnicity after hospitalization for heart failure with preserved ejection fraction. JACC Heart Fail. 2018;6:388-97. doi: 10.1016/j.jchf.2017.12.007. In highly complex conditions, the measure of value and effectiveness can be more multifaceted. In cancer, for example, there are several end-points to measure effectiveness, such as progression- free survival and overall survival. To account for this complexity, cost-effectiveness studies for cancer therapies can measure the value in providing the medication earlier in the course of treatment. An example from our portfolio is IMFINZI--currently the only FDA-approved immunotherapy for the treatment of patients with unresectable stage III non-small cell lung cancer whose cancer has not progressed following platinum-based concurrent chemoradiation therapy. Before IMFINZI, patients in this setting underwent a period of ``watch and wait'' after chemoradiation,\15\ and for up to 89 percent of these patients their cancer was likely to spread further.\16\ Based on the PACIFIC trial, IMFINZI may reduce the risk of death for these patients by nearly a third.\17\ --------------------------------------------------------------------------- \15\ Postmus PE, Kerr KM, Oudkerk M, et al. Early and locally advanced non-small-cell lung cancer (NSCLC): ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up. Annals of Oncol. Published online July 1, 2017. doi: 10.1093/annonc/mdx222. \16\ Albain KS, Swann RS, Rusch VW, et al. Radiotherapy Plus Chemotherapy With or Without Surgical Resection for Stage III Non-Small Cell Lung Cancer. Lancet. Published online August 1, 2009. doi: 0.1016/ S0140-6736(09)60737-6. \17\ Antonia SJ, Villegas A, Daniel D, et al. Overall survival with durvalumab after chemoradiotherapy in stage III NSCLC. N Engl J Med. 2018;379(24):2342-2350. doi: 10.1056/NEJMoa1809697. Epub 2018 Sep 25. In a recent analysis, use of IMFINZI was found to be cost-effective in comparison to the previous ``watch and wait'' approach to treatment. This cost-effectiveness analysis, published in the Journal of the American Medical Association in December 2018, indicates that although IMFINZI consolidation therapy increased national cancer spending, treating earlier in the course of cancer progression may provide significant value.\18\ --------------------------------------------------------------------------- \18\ Criss SD, Mooradian MJ, Sheehan DF, et al. Cost-effectiveness and Budgetary Consequence Analysis of Durvalumab Consolidation Therapy vs. No Consolidation Therapy After Chemoradiotherapy in Stage III Non- Small Cell Lung Cancer in the Context of the U.S. Health Care System. JAMA Oncol. Published online December 13, 2018. doi: 10.1001/ jamaoncol.2018.5449. For a drug therapy to bring the most value to patients and the health-care system, it is imperative that the therapy is reaching the right patients at the right point in their treatment journeys. At AstraZeneca, we are focused on improving outcomes for patients on a personalized level by identifying the most appropriate treatments. Approximately 90 percent of our pipeline now has a precision medicine approach and reflects the broad range of cutting-edge technologies, tissue diagnostics, next-generation sequencing and point of care diagnostics we have introduced. By more precisely matching patients with the right medicine, we bring greater value to payers and the health-care system and help to ensure that patients receive the --------------------------------------------------------------------------- specific therapy that is most appropriate for their treatment needs. Finally, the concept of value is a key component in our pricing determinations. AstraZeneca has always taken a thoughtful approach to pricing, and we continue to do so, considering many factors. In addition to our significant R&D investments, we consider clinical value, size of patient population, government/payer coverage requirements, patient affordability, competition and other market conditions. We remain committed to pricing responsibly and making our medicines available and affordable to patients. iv. commitment to patient access and affordability Although we are thoughtful in our approach to pricing, we know that patients continue to face challenges at the pharmacy counter. We fully recognize that drug therapies cannot bring value to the health-care system or to patients unless they can access the medicines they need. Our commitment to affordable access translates into a number of resources and programs that have helped make our medicines available to patients. A. AstraZeneca Savings and Affordability Programs To ensure that patients in the U.S. are aware of our affordability programs, we were the first company to include messages about these programs in all of our U.S. television advertisements. Since 2005, every televised advertisement has reminded viewers: ``If you can't afford your medication, AstraZeneca may be able to help.'' We stand behind this statement. Forty years ago, we were one of the first manufacturers in our industry to establish a patient assistance program to help low- income patients obtain certain medicines free of charge. Through our ``AZ&Me'' program, we have provided prescription drug savings to more than four million patients in the U.S. and Puerto Rico between 2008 and 2018. In addition to AZ&Me, we offer extensive copay savings programs to help eligible, commercially insured patients reduce copay costs at the pharmacy. These copay savings programs are unfortunately not available to Part D patients and this has created challenges for this population, reducing adherence to important lifesaving or life-improving treatments. B. Value-Based Agreements We are also working closely with payers and health systems to explore innovative solutions to improve access and affordability that demonstrate the value our medicines bring to patients and the health- care system. For several years, AstraZeneca has been exploring these types of solutions through value-based agreements where we are willing to work with health-care stakeholders to tie payment to patient outcomes. To date, we have entered into approximately 40 value-based agreements across our therapeutic areas with a variety of payers, making AstraZeneca a leader in the field of value-based agreements. As an example, AstraZeneca agreed with Express Scripts that for IRESSA, an oral treatment for certain types of lung cancer, we will fully reimburse Express Scripts for discontinued use before the third fill, including if discontinuation occurs because patients did not respond to treatment. While most of these agreements have been focused on securing patient access to our medicines and delivering better patient outcomes, where payers are willing, we are also looking to more directly address patient out-of-pocket affordability through these innovative arrangements. As an example, last month, we announced the initiation of a value- based agreement for University of Pittsburgh Medical Center (``UPMC'') Medicare patients who are prescribed BRILINTA. This value-based contract, which was effective as of January 1, 2019, is groundbreaking in two ways. First, the contract lowers the out-of-pocket costs for a UPMC Medicare Part D patient to approximately $10 for a 30-day supply. Second, what UPMC pays for BRILINTA will vary based on patient outcomes, tying the cost of the drug to its real-world clinical performance. We are currently exploring another value-based agreement in Medicare Part D. In addition to having a significant outcomes-based component, this arrangement would reduce patient out-of-pocket costs. This type of agreement allows patients to access their medicines at a lower out-of-pocket cost and payers to control their overall health- care costs through paying for outcomes. However, there remain significant operational and regulatory hurdles to the broader implementation of value-based agreements. Operational challenges include capturing appropriate data and other capabilities on the part of payers that are needed to successfully execute these arrangements. For example, value-based agreements typically require plans to have systems in place to report measures like adherence and readmissions. While many payers and health systems are evolving to meet the needs of the changing health-care environment, greater investments need to be made in data capabilities. In addition, policy and regulations must advance to support value-based agreements in becoming a standard approach to reimbursement. We believe that there are steps the government can take to address these challenges to help encourage the timely adoption of value-based agreements, including in public sector programs like Medicare. These recommendations are described in more detail in section V of this statement. Through the partnership of payers and policymakers, we look forward to a future where implementation of value-based agreements across public and private payers is widespread. C. Discounts and Rebates Finally, we negotiate rebates and discounts with payers and pharmacy benefit managers (``PBMs'')--including in Medicare Part D--to help ensure that our therapies have the most robust access possible. Without providing these discounts and rebates, many life-savings medicines would not be placed on plan formularies and therefore would be largely unavailable to the patients who need them most. Our estimates for 2018 show that across our products, our average rebate is nearly 50 percent of our gross revenues in the U.S. Taking BRILINTA as an example, approximately one third of gross revenue is provided back in rebates. For most of our diabetes therapies, rebates well exceed 50 percent of gross revenues. Over the past several years, discounts and rebates for our therapies have increased overall, both in the commercial sector and Part D. In recent years, in our primary care portfolio, which includes the majority of our therapies, we have seen flat to declining net effective prices to AstraZeneca for most of our products. Taking CRESTOR as an example, in the 5-year period before it lost exclusivity, even though list price increased, in 2011, CRESTOR's average net effective price earned by AstraZeneca was $2.52 per day (one pill per day). In 2016 when CRESTOR lost exclusivity, the average net effective price was again $2.52. However, discounts and rebates do not necessarily translate to lower cost-sharing for patients. There are a series of factors that impact a patient's out-of-pocket costs, including individual insurance plan benefit design (copayments, coinsurance, and deductibles), formulary placement, provider access, and assistance programs or savings offers. As a science-led, patient-focused company, the fact that many patients struggle with out-of-pocket costs despite the discount and rebates we provide stands counter to our mission of improving patient health. v. the path forward: evolving the current system Despite rapidly increasing rebate amounts, affordability of drug therapies is an increasingly significant public policy and public health issue. We agree that the current system is not sustainable--for patients, payers, and society as a whole--and we are committed to engaging across stakeholders to develop a new paradigm that improves affordability and access for patients while ensuring that manufacturers can continue to develop innovative therapies. To achieve these goals of improving affordability and supporting innovation, we must progress from a volume-based to a value-based health-care system. We continue to be forward-leaning in this regard, and we encourage other stakeholders to join us in the effort to deliver and pay for health care, including drug therapies, in a more affordable, efficient, and effective way. An important step is to evolve the current system of paying for and delivering drug therapies to one in which patients more directly benefit from the discounts and rebates we provide. Specifically, we believe that patient cost-sharing should be more aligned to a product's net price as opposed to its list price, as is the case today. However, as we look ahead to the future, even more must be done to improve patient affordability and to truly build a health-care system based on the value of therapies provided to patients. A. Value-Based Agreements Should Be the Future Standard First, in a future system, the default approach should be that pricing and reimbursement for drug therapies are tied to patient outcomes and the value the particular therapy provides. As such, it is imperative that manufacturers and payers--including Part D plans-- engage in value-based agreements similar to the IRESSA and BRILINTA examples referenced previously. Policies to encourage these arrangements and to reduce or eliminate existing challenges will be essential to their long-term success. To that end, AstraZeneca appreciates the support of Senators Warner and Cassidy for value-based agreements, as demonstrated by their requests for input on the Patient Affordability Value and Efficiency (``PAVE'') Act. This draft legislation would promote the development of value-based agreements by offering increased flexibility for manufacturers to enter into such arrangements, including with Medicare Part D plans. In addition to the policies outlined in the PAVE Act, there are other ways that the government could facilitate value-based agreements. For example, the Department of Health and Human Services (``HHS'') should consider how its recent proposed rule regarding PBM rebates can be structured to protect existing and future value-based agreements. We appreciate that HHS solicited comments on this topic, and we look forward to sharing our perspective in our written comments to the proposal. In addition, to encourage utilization of agreements that best address the government's goals, we recommend that HHS develop a prioritized list of clinical outcomes measures for manufacturers and payers to consider when developing outcomes-based agreements. Over the past several years, we have engaged with HHS, and specifically the Center for Medicare and Medicaid Innovation (``CMMI''), to advance specific models involving our therapies in the Medicare program. To date, we have not been able to execute on a model with HHS or CMMI and the feedback we have received is that company- specific models are challenging to implement. We look forward to continued dialogue on these issues, and we hope to work with HHS, CMMI and other stakeholders to develop a scalable framework in which innovative models can be implemented in an appropriate way. B. All Patients, Including Medicare Patients, Should Benefit From Reduced Cost-Sharing Second, a future system should be designed to ensure that all patients benefit from lower cost-sharing, including those patients taking drug therapies on the Part D specialty tier. A recent study found that rates of prescription abandonment and delayed initiation of oral cancer therapies increase as cost-sharing amounts rise.\19\ Such a result reflects the need for a restructuring of the current benefit design for specialty products. --------------------------------------------------------------------------- \19\ Doshi JA, Li P, Petit AR, et al. Association of Patient Out- of-Pocket Costs With Prescription Abandonment and Delay in Fills of Novel Oral Anticancer Agents. J Clin Oncol. 2018; 36(5): 476-482. doi: 10.1200/JCO.2017.74.5091. Under one potential approach, a portion of manufacturer discounts could be used to fund a reduction in cost-sharing for patients facing the highest cost-sharing amounts. This could be accomplished by establishing a monthly or annual out-of-pocket cap, which would give patients greater certainty in the total amount of out-of-pocket costs they could face. The cap would provide a safety-net for patients that could be funded by a portion of the discounts provided across all Part D products. Such an approach would help ensure that more patients benefit from the discounts manufacturers provide. C. Use of Biosimilars Should Be Supported Third, we believe that competition is a key component to reducing costs, and that is why we support expanded use of biosimilars in the U.S. As a global company, we operate in countries, particularly those in the European Union, where biosimilar competition is particularly robust. We support a similarly vigorous biosimilars market in the U.S. We therefore appreciate the efforts of the FDA to increase the availability of biosimilars in the U.S., including the FDA's development of a Biosimilars Action Plan. We support efforts to streamline and improve the efficiency of the biosimilars approval pathway for the benefit of patients. We also support reimbursement policies that facilitate the uptake of biosimilars. Such policies include Medicare reimbursement rates that ensure that biosimilars can compete on equal footing with innovator products. d. market-based competition should be maintained Finally, it is imperative to maintain market-based competition between manufacturers and between plans. Market-based competition plays an important role in keeping costs down. This is how the lifecycle of innovator therapies works today when competitors enter the market and generic medicines become available over time. The competitive market in the U.S. also provides patients with access to innovative medicines faster. For example, American patients have access to cancer medicines about 2 years earlier than patients in other countries, including Germany, France, and the U.K.\20\ This timely access to new cancer therapies is correlated with improved survival rates; from 1997 to 2012, rates of cancer mortality fell by 20 percent in the U.S., compared to a 15 percent reduction in the U.K.\21\ Additionally, nearly 90 percent of newly launched medicines from 2011 to 2017 were available in the U.S., compared to just two-thirds in the U.K., half in Canada and France, and one-third in Australia; and of 14 new diabetes medicines launched over that period, only one was available in France.\22\ Given the benefits brought to patients by new antidiabetic agents such as SGLT2 inhibitors (reduction in heart failure and hospitalizations for heart failure), U.S. patients and payers greatly benefit from the earlier introduction of these innovative medicines. --------------------------------------------------------------------------- \20\ PhRMA analysis of IMS Consulting Group ``Patient Access to Innovative Oncology Medicines Across Developed Markets.'' June 2016. \21\ World Health Organization (WHO). WHO mortality database. http://www.who.int/healthinfo/mortality_data/en. PhRMA analysis of WHO mortality database, using age--specific death rates. \22\ PhRMA analysis of IQVIA Analytics. While the current system needs reform, some of the benefits to the current structure are the speed of access and reimbursement of new medicines and the robust nature of the negotiations between manufacturers and PBMs, which in turn creates competition between manufacturers. As the system evolves, it is important that this ability to compete is maintained. Therefore, there must be flexibility to continue to negotiate net price by product and indication, among other --------------------------------------------------------------------------- factors. This flexibility is necessary not only to maintain competition, but also to facilitate additional innovations in the way drugs are priced and reimbursed. For example, variable discounts could be used to reduce cost-sharing for patients over time as they remain adherent to their medications. Additionally, we support the concept of indication-based pricing, which recognizes that the value of a drug therapy with more than one indication may vary based on indication. Indication-based pricing would allow greater competition among manufacturers based on the clinical efficacy of their therapies on an indication-by-indication basis. Allowing discounts to vary based on the indication for which a therapy is prescribed will be key to facilitating indication-based pricing. Finally, we would like to acknowledge that the coverage and reimbursement policies in Medicare Part B have been criticized for not sufficiently encouraging price competition for physician-administered drug therapies. We are supportive of reforms in the Medicare Part B program to address these concerns. Such reforms could include an inflation penalty if a manufacturer's price increase exceeds a certain threshold, as well as steps to ensure that the government and Medicare patients more directly benefit from the discounts and rebates provided in the commercial sector. Similar to the suggestion above on creating a Part D out-of-pocket cap funded by a portion of manufacturer discounts, the savings generated from an inflation penalty and increased competition in Part B could be used to fund an out-of-pocket cap for Medicare Part B patients. Competition is a fundamental requirement to reducing costs over time, both in Medicare Part B and Part D. Flexibility in the future system will be necessary to maintain competition and to explore additional innovations in the pricing and reimbursement of drug therapies. We must also be willing to work together to improve the efficiency of the Part B program. We look forward to working with policymakers and other stakeholders to shape the future system to accomplish these goals. vi. conclusion Although there is no single solution to the challenges we face, we welcome the opportunity to speak with you about ways to evolve our health-care system. We share your concern that many patients are facing challenges with out-of-pocket costs, and we are committed to working towards solutions that support patient access and affordability while sustaining innovation. AstraZeneca, along with many others in the pharmaceutical industry, is innovating to discover and develop tomorrow's cures and treatments, and we know we need to be a constructive partner to find solutions to ensure that patients benefit from the therapies we develop. ______ Questions Submitted for the Record to Pascal Soriot Questions Submitted by Hon. Chuck Grassley Question. At the hearing, you testified that AstraZeneca does not withhold samples from generic manufacturers in order to block generic versions of your drug from entering the market. You also expressed your support for the ``Creating and Restoring Equal Access to Equivalent Samples Act,'' also known as the CREATES Act. However, the FDA has a list on its website which identifies reference listed drug (RLD) access inquiries where brand manufacturers may have prevented generic companies from obtaining samples of products necessary to support FDA approval. AstraZeneca is on this FDA list. This would appear to contradict your testimony at the hearing that AstraZeneca has not withheld samples of their products to delay generic competition. Could you please explain in detail why AstraZeneca is on the FDA list? Answer. AstraZeneca appreciates the opportunity to address the question of one of our medicines, BRILINTA (ticagrelor) appearing on the Reference Listed Drug Access Inquiries list (RLD List). We would first like to state that AstraZeneca supports allowing generic manufacturers access to samples. Withholding or otherwise blocking such access is inconsistent with that position. Our internal review has not identified any unanswered, delayed, or outstanding requests for samples of BRILINTA by any generic manufacturers. It is our understanding that BRILINTA was included on the RLD List based on a single inquiry received by the FDA. Unfortunately, the RLD List does not identify the company that reportedly requested information (or samples) from AstraZeneca, the date the information was requested, or any other information that would allow AstraZeneca to better understand or further investigate the circumstances of this inquiry. On its website, the FDA does advise that it has ``not independently investigated or confirmed the access limitations described in the inquiries received.'' \1\ Given this limitation, the listing of an inquiry on the RLD List does not mean that the FDA has in fact determined that access to samples by generic manufacturers was limited or withheld for the medicines identified. Indeed, based on our internal review, we have not identified any circumstances that substantiate the inquiry received by the FDA relating to BRILINTA. --------------------------------------------------------------------------- \1\ Reference Listed Drug (RLD) Access Inquiries, U.S. Food and Drug Administration, https://www.fda.gov/Drugs/ DevelopmentApprovalProcess/HowDrugsareDevelopedandApproved/ ApprovalApplications/AbbreviatedNewDrugApplicationANDAGenerics/ ucm607738.htm (last updated Feb. 7, 2019). Question. Could you please explain in detail the discrepancy --------------------------------------------------------------------------- between your testimony and the FDA list? Answer. AstraZeneca is not aware of any instances where the company has withheld or otherwise blocked access to samples by generic manufacturers. Based on our internal review, AstraZeneca is not aware of any unanswered, delayed, or outstanding requests for samples of BRILINTA by any generic manufacturers. In addition, BRILINTA is and has always been available via normal commercial distribution channels (i.e., wholesalers) since its U.S. launch. It has never had a restricted distribution program. Finally, more than 15 generic manufacturers have applied for regulatory approval from the FDA for the manufacture of generic ticagrelor and some, like Watson/Teva, have received tentative approvals from the FDA. Because conducting bioequivalence studies with the branded medicine is an FDA pre-approval requirement, it is clear that these generic manufacturers are not having difficulty accessing branded ticagrelor for their studies. In light of the context provided above, it is unclear why any generic manufacturer would be unable to obtain a sample of BRILINTA for their purposes or why an inquiry was lodged with the FDA related to this medicine. Question. Has AstraZeneca ever blocked access to samples? Answer. AstraZeneca is not aware of instances where the company has refused to sell samples or has otherwise blocked access to samples by generic manufacturers. Question. The Department of Health and Human Services' proposed rule, ``Fraud and Abuse; Removal of Safe Harbor Protection for Rebates Involving Prescription Pharmaceuticals and Creation of New Safe Harbor Protection for Certain Point-of-Sale Reductions in Price on Prescription Pharmaceuticals and Certain Pharmacy Benefit Manager Service Fees,'' envisions that drug manufacturers will offer up-front discounts rather than the back-end rebates that are now commonly provided. Some observers argue that a 1996 court case called into question whether manufacturers could offer up-front discounts, resulting in today's rebate-based system. I've heard differing opinions as to whether the issues related to the initial court case are still relevant. If the HHS proposed rule is finalized, can you assure the committee that your company will offer up-front discounts? If not, why? Answer. If the HHS proposed rule is finalized largely as proposed, AstraZeneca intends to comply with its requirements and use point-of- sale discounts. Question. Please describe how you expect your company to respond to the HHS proposed rule to eliminate safe harbor protection for back-end rebates in Medicare Part D that is referenced above if it is finalized. Assuming you are confident that antitrust laws do not prevent your company from offering up-front discounts, specifically, do you envision that your company lowers the list price of a drug to the current after- rebate net price, offer discounts equal to the current rebate amount, or a combination of both? Answer. Assuming the HHS rebate rule is finalized largely as proposed, AstraZeneca intends to comply with its requirements and use point-of-sale discounts. Our goal is to maintain net prices broadly in line with today, recognizing our ability to do so may be dependent on external factors and market response such as how plans evolve their benefit design and the total degree of transparency under the new model. AstraZeneca would plan to reduce list prices, pending reforms across all payers, including in the commercial sector in addition to Part D, as the current construct does not allow for two separate list prices (i.e., one list price for Part D and a different list price for the commercial sector). Therefore, we also support efforts to eliminate rebates in the commercial sector, and recommend that Congress explore such legislation. While eliminating rebates is an important step, benefit designs must also be evaluated. Question. To what extent are the back-end rebates your company currently offers contingent on the amount of market share realized for your drugs as a result of Part D plan formulary placement and other techniques? Answer. Our arrangements in Part D do not include a market share component. Question. Please provide a breakdown of percentage of sales that go to each payer (including Medicare, Medicaid, private pay, other) and a similar percentage by volume of the total number of each drug compared to total volume. Please provide this data for the most recent year available. Answer. Below you will find our estimated relative payer split of Gross Product Sales in the U.S., for the year ending December 31, 2018. ------------------------------------------------------------------------ Total Products ----------------------------- Sales $ Millions Proportion of Total Payer Business ------------------------------------------------------------------------ Medicaid 1,826,337 11.0% ------------------------------------------------------------------------ Fed Gov't (VA, DOD, CDC, 2,986,585 18.1% PHS) ------------------------------------------------------------------------ GPO/LTC 1,362,663 8.2% ------------------------------------------------------------------------ Commercial 5,019,907 30.4% ------------------------------------------------------------------------ Medicare Part D 3,514,858 21.3% ------------------------------------------------------------------------ Tricare 70,799 0.4% ------------------------------------------------------------------------ Non-Contracted Sales/Other 1,756,851 10.6% ------------------------------------------------------------------------ Total 16,538,000 100.0% ------------------------------------------------------------------------ Question. Do your companies hire consultants or lobbyists to promote products at State Medicaid Pharmacy and Therapeutics Committees? To whom do you disclose advocacy activities surrounding State Medicaid programs, if at all? Answer. AstraZeneca does not utilize consultants or lobbyists to promote medicines at State Pharmacy and Therapeutics (P&T) Committees. However, AstraZeneca Medical Affairs personnel may engage in peer-to- peer medical discussions with members of the medical community including Medicaid P&T committee members. AstraZeneca has comprehensive internal policies that oversee interactions between AstraZeneca employees and government officials. Federal and state laws and regulations also govern lobbying activities, and AstraZeneca complies with the attendant disclosure requirements. Question. Please describe how the costs of patient assistance programs are accounted for within your company's financial statements. Please also describe the types of market information, such as prescribing and use patterns, that your company collects from different types of patient assistance programs and patient hub services. Answer. AZ&MeTM Prescription Savings Program (Patient Assistance Program): In furtherance of its objective of ensuring patient access, AstraZeneca was one of the first manufacturers in the industry to establish a patient assistance program to facilitate access to certain medicines for uninsured and underinsured low-income patients. This program, known as AZ&Me, provides eligible patients with medicines at no cost. We account for the costs of medicines provided through the AZ&Me program as a component of our Operating Expenses. In connection with the AZ&Me program, AstraZeneca collects general program enrollment data such as number of patients in the program and medicine provided. Access 360TM (Patient Hub): AstraZeneca's patient hub, Access 360, is a reimbursement support program that provides patients and their healthcare providers with limited access and reimbursement support for AstraZeneca specialty care medicines. Access 360 collects patient, provider and payer coverage data in conjunction with appropriate patient opt-ins to administer the limited reimbursement services offered by the program. Question. Please provide a list of all contributions since January 1, 2014, that your company has made to any tax exempt organizations working on issues related to drugs within your product lines, including but not limited to patient groups, disease awareness groups, medical or professional societies, universities or hospitals, industry associations or leagues. For each contribution, please provide the name of the organization that received the donation, the date the donation was made, the amount of the donation, and a description of the purpose of the contribution (i.e., was the contribution for the general fund, a specific purpose to a specific program, or continuing medical education). Please also note whether the contribution was unrestricted or restricted; if it was restricted, please explain all restrictions. Finally, if your company maintains a foundation or other separate charitable arm, please provide the name of all such entities, and list all donations made from that entity or entities. Answer. Our commitment to improving the lives of patients goes beyond our innovative medicines. We place significant value on collaboration and partnerships, including work done by non-profits, patient advocates, medical professionals, and researchers. To that end, we provide support for eligible programs through corporate contributions, research support, fellowships, and medical education grants. We also support conferences and initiatives for healthcare professionals and scientists. AstraZeneca believes in providing information to the public about our company, our medicines and about how we do business. In 2008, we began publishing biannual reports of our contributions to nonprofit organizations. We use contributions as our umbrella term for financial support to nonprofit organizations contributing to the public good (e.g., donations, sponsorships, and partnerships). The below data reflects the total value of contributions made by AstraZeneca to nonprofit organizations in the U.S. in the years 2014- 2018. A full list of contributions, including the recipient organization, associated program name, and amount of each contribution, can be found here: https://www.astrazeneca-us.com/sustainability/ Corporate-transparency/grants-and-contributions-disclosure.html. 2018: $18.3 million 2017: $5.5 million 2016: $10.9 million 2015: $19.8 million 2014: $15.5 million In addition, in 1993, AstraZeneca founded the AstraZeneca HealthCare Foundation, a 501(c)(3) entity. The AstraZeneca HealthCare Foundation aims to promote public awareness surrounding healthcare issues, further public education and medical knowledge, and support charitable and qualified exempt organizations whose work aligns with the Foundation's charitable goals. In furtherance of AstraZeneca's commitment to improving health, in 2010 the AstraZeneca HealthCare Foundation launched the Connections for Cardiovascular HealthSM (CCH) program. With the mission of improving cardiovascular health in the U.S., CCH awards grants to U.S.- based nonprofit organizations whose work supports CCH's mission. Since its launch, CCH has awarded nearly $23 million to 52 organizations working to prevent cardiovascular disease. The below data reflects the approximate total value of grants made by CCH per year between 2014 and 2018. A full list of grants, including the recipient organization, associated program name, and amount of each contribution, can be found here: https://www.astrazeneca-us.com/ sustainability/healthcare-foundation/connections-for-cardiovascular- health.html#past-grant-awardees--0. 2018: $1.2 million 2017: $993,880 2016: $1.8 million 2015: $1.9 million 2014: $2.6 million AstraZeneca also awards medical education grants and scientific sponsorships. These grants are offered to support independent medical education, scientific sponsorships, and fellowship or healthcare professionalin-training. Grants are offered for conduct of programs, are awarded on the basis of individual applications through our medical education grants process, and are not conditioned on services. This process and all grant decisions are managed independently within our Medical Affairs group and have no connection to our sales and marketing departments. The below data reflects the approximate total value of medical education grants made by AstraZeneca per year, since 2014. A full list of medical education grants offered to non-profit organizations, including the recipient organization, associated program name, date, and amount of each contribution, can be found in Appendix A. 2018: $28.9 million 2017: $17.5 million 2016: $11.6 million 2015: $24.9 million 2014: $14.8 million Question. Pay-for-delay agreements cost consumers and taxpayers billions in higher drug costs every year. The FTC has gone after drug companies that enter into these settlements where the brand pays the generic company to keep its lower cost alternative off the market. I'm the lead Republican sponsor of S. 64, the Preserve Access to Affordable Generics and Biosimilars Act, which would help put an end to these deals. Do you agree that these pay-off agreements keep drug costs high for patients because they delay competition? Answer. AstraZeneca has confidence in patents that protect our medicines and, where appropriate, we file lawsuits to protect our intellectual property. AstraZeneca does not enter into ``pay-off agreements,'' if those are understood to include settlements that pay generic competitors to delay entry into the market. AstraZeneca engages in patent settlements but we do not believe these resolutions contribute to increased prices. In the absence of a settlement, a generic would not necessarily prevail in the patent litigation and therefore would not be able to enter the market. Indeed, AstraZeneca has entered into many early-entry patent settlements that allow generic manufacturers to license innovator patents and thereby permit generic competition before expiration of AstraZeneca's patent rights. Settlement agreements that permit entry of generic drugs before expiration of relevant patent rights do not stifle competition but instead permit early entry by resolving patent disputes that would otherwise prevent generic alternatives to branded medication. All of AstraZeneca's patent settlements fully comply with the law. These settlements provide increased clarity and stability to both parties, allowing innovators like AstraZeneca to continue investing substantially in new medicines for patients and frequently allowing generic competitors to enter the market before expiration of AstraZeneca's patent rights. Question. Has your company ever entered into these kinds of settlements with a generic company? Answer. AstraZeneca does not enter into settlements that pay generic competitors to delay entry into the market. Question. Do you support the pay for delay bill? Answer. While AstraZeneca supports efforts to curb patent settlement abuses, we have concerns about the Preserve Access to Affordable Generics and Biosimilars Act in its current form. For example, the proposed legislation would be retroactive to 2013 and would unfairly subject to potential scrutiny lawful settlements entered into based on the then existing legal construct. As a general matter, AstraZeneca believes that patent settlement agreements are pro- competitive because they can permit entry of generic drugs before expiration of relevant patent rights. rebate traps/walls Question. I'm increasingly concerned about the effect of so-called ``rebate traps'' or ``rebate walls'' on patients' access to quality, lower cost medicine. I understand there is ongoing litigation challenging these practices as anti-competitive. Does your company engage in the bundling of rebates over multiple products? If so, why? And what benefit does the consumer gain from that? Answer. AstraZeneca offers portfolio discount arrangements to improve patient access and affordability across multiple medicines, thus ensuring the right medicine can be prescribed for the right patient. Portfolio discounting allows manufacturers and plans another mechanism to negotiate for formulary access for the patient, in addition to single-medicine discounts and rebates. Irrespective of the approach to discounting, AstraZeneca also ensures discounts are appropriately reported in government price reporting metrics (e.g., Best Price, Average Manufacturer Price, and Average Sales Price). Question. Does your company view these practices as anticompetitive or harmful to patients' access to quality, lower cost medicine? Answer. AstraZeneca does not view these practices as anticompetitive or harmful to patients' access. In fact, AstraZeneca offers portfolio discount arrangements to improve patient access and affordability. Question. If a policy were adopted to eliminate rebates, or to require that rebate savings be passed on to the consumer, would that in and of itself solve the issue of rebate ``traps'' and ``walls''? And would consumers benefit from such a policy? Answer. AstraZeneca believes that evolving the current system of paying for and delivering drug therapies to one in which patients more directly benefit from the discounts and rebates that AstraZeneca provides is an important step towards improving affordability and supporting innovation. This can best be accomplished by eliminating rebates in Medicare Part D and the commercial sector, which would create competition between manufacturers on net price instead of rebate amounts, thereby helping to eliminate rebate ``traps'' and ``walls.'' AstraZeneca also believes that patient cost-sharing should be more aligned to a medicine's net price, and that eliminating rebates and moving to a point-of-sale discount model should help accomplish this goal. Additionally, it is important to note that lowering list prices in the U.S. without addressing broader challenges, including benefit design, will not improve affordability for many patients. While eliminating rebates is an important step, benefit designs must also be evaluated. drug pricing Question. When setting the list price of a drug, does your company consider regulatory costs or compliance? If so, how specifically do those factors affect the list price of a drug? Please provide at least one specific example, if applicable, from your current product portfolio. Answer. AstraZeneca does not directly consider regulatory or compliance costs when setting the list price of a drug. AstraZeneca's approach to pricing across all medicines is driven by a number of factors, including clinical value, patient access and affordability, patient population, government and payer coverage requirements, RandD expenditures, manufacturing costs, and competitive dynamics. AstraZeneca is mindful of healthcare costs and is continuously exploring innovative opportunities and solutions to deliver medicines while considering cost and value. In setting drug prices, AstraZeneca takes into account both the budget impact to payers (including Medicare and pharmacy benefit managers (PBMs)) as well as patient out-of-pocket costs to maintain patient access to needed medication. AstraZeneca has also been a leading innovator in developing alternate payment structures for its medicines. In particular, AstraZeneca has emphasized value-based agreements, which, broadly speaking, seek to link access, reimbursement or price, to a demonstrated clinical benefit or outcome. Question. When setting the list price of a drug, does your company consider the risk of liability or litigation? If so, how specifically do those factors affect the list price of a drug? Please provide at least one specific example, if applicable, from your current product portfolio. Answer. AstraZeneca does not consider the risk of liability or litigation when setting the list price for a particular drug. ______ Questions Submitted by Hon. Pat Roberts Question. What role do you see value-based arrangements (VBAs) playing in the effort to reduce prescription drug costs? What potential do these arrangements have to find the ``sweet spot'' between controlling costs to patients and encouraging innovation of new drugs? Answer. We believe medicines are part of the solution to controlling health-care costs. They not only improve patient outcomes and increase quality of life, but also reduce downstream costs. Value- based agreements allow us to reimburse the health-care system if our medicines do not deliver as intended. This solution demonstrates our willingness to stand behind the value of our medicines. AstraZeneca is working closely with payers and health systems to explore innovative solutions to improve access and affordability that demonstrate the value our medicines bring to patients and the health- care system. Our value-based agreements aim to manage the totality of treatment costs and keep people healthy and out of the hospital. For several years, AstraZeneca has been exploring these types of solutions through value-based agreements where we are willing to work with health-care stakeholders to tie payment to patient outcomes. To date, we have entered into approximately 40 value-based agreements across our therapeutic areas with a variety of payers, making AstraZeneca a leader in the field of value-based agreements. As an example, and as noted in the written testimony submitted to the Senate Committee on Finance, AstraZeneca agreed with Express Scripts that for IRESSA, an oral treatment for certain types of lung cancer, we will fully reimburse Express Scripts for discontinued use before the third fill, including if discontinuation occurs because patients did not respond to treatment. Question. How can VBAs help lower what patients pay out-of-pocket? Answer. While most of these agreements have been focused on securing patient access to our medicines and delivering better patient outcomes, where payers are willing, we are also looking to more directly address patient out-of-pocket affordability through these innovative arrangements. Our ambition is that these agreements will evolve to enable reimbursement back to a payer to be shared with the patient when medicines do not perform as expected. As an example where a value-based agreement directly reduced out- of-pocket costs for patients, we recently announced the initiation of a value-based agreement for University of Pittsburgh Medical Center (UPMC) Medicare patients who are prescribed BRILINTA. This value-based contract, which was effective as of January 1, 2019, is groundbreaking in two ways. First, the contract lowers the out-of-pocket costs for a UPMC Medicare Part D patient to approximately $10 for a 30-day supply. Second, what UPMC pays for BRILINTA will vary based on patient outcomes, tying the cost of the medicine to its real-world clinical performance. We are currently exploring another value-based agreement in Medicare Part D. In addition to having a significant outcomes-based component, this arrangement would reduce patient out-of-pocket costs. This type of agreement allows patients to access their medicines at a lower out-of-pocket cost and payers to control their overall healthcare costs through paying for outcomes. Question. Can Congress do more to allow for and encourage the use of VBAs? Answer. We believe that there are steps the government can take to address challenges and help encourage the timely adoption of value- based agreements, including in public sector programs like Medicare. For example, at this time, the current Anti-Kickback Safe Harbor (AKS) regulations do not expressly address value-based agreements. Accordingly, manufacturers must seek to structure value-based agreements to meet the requirements of existing safe harbors from the AKS, such as the discount safe harbor and personal services safe harbor, that were created for purposes other than value-based agreements. Although we believe that value-based agreements can strongly benefit patients and the health-care system overall, the lack of clarity in application of the safe harbors to value-based agreements creates regulatory uncertainty that discourages broader implementation of value-based agreements in public-sector programs. In addition to the risk of AKS liability, value-based agreements present other regulatory challenges that manufacturers must navigate. For example, manufacturers must manage complex government price reporting calculations that may not account for price fluctuations over time that may be associated with a value-based agreement. In a future system, the default approach should be that pricing and reimbursement for drug therapies are tied to patient outcomes and the value the particular therapy provides. As such, it is imperative that manufacturers and payers--including Medicare plans--engage in value- based agreements similar to the IRESSA and BRILINTA examples referenced previously. Policies to encourage these arrangements and to reduce or eliminate existing challenges will be essential to their long-term success. To that end, AstraZeneca appreciates the support of Senators Warner and Cassidy for value-based agreements, as demonstrated by their requests for input on the Patient Affordability Value and Efficiency (PAVE) Act. This draft legislation would promote the development of value-based agreements by offering increased flexibility for manufacturers to enter into such arrangements, including with Medicare Part D plans by addressing AKS and government pricing concerns. This legislation is particularly important given the administration's proposal to eliminate PBM rebates under the discount safe harbor. Currently, many value-based agreements are structured using a rebate agreement, under which the terms of a discount are based on clinical or cost outcomes measures. Therefore, the elimination of discount safe harbor protection for rebates without an exception for value-based agreements could inadvertently reduce incentives for value- based agreements, which we do not believe is the administration's intent. We have therefore recommended to HHS that value-based agreements are exempt from the proposed changes to the discount safe harbor and we encourage members of Congress to support this exemption. Through the partnership of payers and policymakers, we look forward to a future where implementation of value-based agreements across public and private payers is widespread. ______ Questions Submitted by Hon. John Cornyn Question. We continue to hear that rebates negotiated off of the list price of a drug are both good and bad. Pharmacy benefit managers and plans have argued that rebates are used to lower premiums across the board and that it is the best way to seek a price concession on otherwise expensive drugs. Your industry argues that these payers are insisting on higher rebates that can only be achieved by raising list prices. But patients often lose under this system, with out of pocket costs being tied to list price. Insulin patients appear to be routinely impacted by this perversity in the system. Please explain to the committee how your company would reduce list prices if rebates were no longer a part of the equation? Answer. Assuming the HHS rebate rule is finalized largely as proposed, AstraZeneca intends to comply with its requirements and use point-of-sale discounts. Our goal is to maintain net prices broadly in line with today, recognizing our ability to do so may be dependent on external factors and market response such as how plans evolve their benefit design and the total degree of transparency under the new model. AstraZeneca would plan to reduce list prices, pending reforms across all payers, including in the commercial sector in addition to Part D, as the current construct does not allow for two separate list prices (i.e., one list price for Part D and a different list price for the commercial sector). Therefore, we also support efforts to eliminate rebates in the commercial sector, and recommend that Congress explore such legislation. While eliminating rebates is an important step, benefit designs must also be evaluated. Question. What assurance can you provide that you would in fact lower your prices? Answer. Assuming the HHS rebate rule is finalized largely as proposed, AstraZeneca intends to comply with its requirements and use point-of-sale discounts. Our goal is to maintain net prices broadly in line with today, recognizing our ability to do so may be dependent on external factors and market response such as how plans evolve their benefit design and the total degree of transparency under the new model. AstraZeneca would plan to reduce list prices, pending reforms across all payers, including in the commercial sector in addition to Part D, as the current construct does not allow for two separate list prices (i.e., one list price for Part D and a different list price for the commercial sector). Therefore, we also support efforts to eliminate rebates in the commercial sector and recommend that Congress explore such legislation. While eliminating rebates is an important step, benefit designs must also be evaluated. Question. What actions should be taken to ensure that patients are actually seeing the benefits of lower out-of-pocket costs? Answer. In the absence of rebates, the market incentives for the differential between list and net price should be reduced because manufacturers will be competing on the basis of net price instead of rebate amounts. Because Part D patient cost-sharing is currently based on list price and not net price, this change may also result in lower cost-sharing for patients. Additionally, it is important to note that lowering list prices in the U.S. without addressing broader challenges, including benefit design, will not improve affordability for many patients. While eliminating rebates is an important step, benefit designs must also be evaluated. AstraZeneca also supports monthly and annual out-of-pocket caps in Medicare Part D to further ensure that patients see the benefits of lower out-of-pocket costs. Question. If rebates are driving high list prices for drugs as drug manufacturers' claim, why do you think that Part B drugs, which have no PBM rebates, are also seeing significant price increases? Whose fault is that? Answer. For our Part B products, price increases are modest and generally in line with inflation. We are supportive of competition, including policies that support more widespread use of biosimilars. ______ Questions Submitted by Hon. Steve Daines Question. As an advocate for improving Montanans' access to low- cost medications, I've been a champion of the Creating and Restoring Equal Access to Equivalent Samples (CREATES) Act, which would combat anticompetitive practices used by some brand-name pharmaceutical companies to block or delay competing generic drugs from entering the market. During the hearing when I asked if your company had ever withheld samples from generic manufacturers, you answered emphatically no. Yet, according to the Food and Drug Administration (FDA), generic drug makers have made inquiries with the agency claiming they were unable to access samples provided by Pfizer and AstraZeneca that are needed to conduct studies to produce low-cost generic drugs. Do you agree that denying generic drug manufacturers access to samples keeps drug costs high for patients due to lack of competition? Answer. AstraZeneca is supportive of allowing generic manufacturers to have access to samples. Question. Has your company refused to sell samples or placed any barriers in the way of generic drug makers acquiring samples? Answer. AstraZeneca is not aware of instances where the company has refused to sell samples or has otherwise blocked access to samples by generic manufacturers. Question. Are you aware of any outstanding requests for samples? Answer. AstraZeneca is not aware of any unanswered, delayed, or outstanding requests for samples of our medicines by generic manufacturers. It is our understanding that one of our medicines, BRILINTA, was included on the Reference Listed Drug Access Inquiries List (RLD List) based on a single inquiry received by the FDA. However, BRILINTA has always been available via normal commercial distribution channels (i.e., wholesalers) and has never had a restricted distribution program. Unfortunately, the RLD List does not identify the company that reportedly requested information (or samples) from AstraZeneca, the date the information was requested, or any other information that would allow AstraZeneca to better understand or further investigate the circumstances of this inquiry. On its website, the FDA does advise that it has ``not independently investigated or confirmed the access limitations described in the inquiries received.'' Given this limitation, the listing of an inquiry on the RLD List does not mean that the FDA has in fact determined that access to samples by generic manufacturers was limited or withheld for the medicines identified. Indeed, based on our internal review, we have not identified any circumstances that substantiate the inquiry received by the FDA relating to BRILINTA. Question. How does your company work to prevent abuses in the sample system? Answer. AstraZeneca is supportive of allowing generic manufacturers to have access to samples and is not aware of instances that would be considered abuse of the samples system. ______ Questions Submitted by Hon. Todd Young re-evaluating business strategies in foreign countries Question. Since taking office, President Trump has made reducing drug prices one of his highest priorities--and has repeatedly spoken about his frustration with the U.S. subsidizing the costs of pharmaceuticals for the rest of the world. He has gone so far as to issue proposals, like the International Pricing Index (IPI) Model, in an attempt to bring down prescription drug prices. With the increased scrutiny of the industry and of the drug supply chain as a whole in the United States, have any of your companies re-evaluated your business strategy in foreign countries? Answer. We continuously evaluate our business approaches in all markets and adjust our strategies accordingly based on many factors, including the overall environment. Question. If not, then why? Answer. See response above. Question. If a proposal, like IPI, were implemented, would it force your companies to potentially ``walk away from the negotiating table when other countries demand low prices subsidized by America's seniors,'' as HHS Senior Advisor for Drug Pricing Reform John O'Brien has said? Answer. If the IPI model were put into effect as proposed, where an identified average international price would be derived from 16 countries, this would impact our ability to sell our medicines in some of the identified markets. The IPI model was issued as an Advanced Notice of Proposed Rulemaking (ANPRM). Important details such as the medicines that would be included in the model, the final list of nations included as reference countries, and the timing of reimbursement changes are still unknown. We look forward to engaging with policymakers on this proposal. Question. What are some of your ideas on how we can ensure Americans aren't shouldering the full cost of pharmaceuticals? Answer. We agree that out-of-pocket costs are unsustainable in the U.S., but the answer is not to move to a system found in other countries or to link pricing in the U.S. to the International Pricing Index. It is critical to recognize that while price controls are the default in many other countries, these price controls result in reduced access to important medicines. In the 16 countries referenced in the International Pricing Index model proposal, only 55 percent of new cancer medicines are available, compared to 96 percent in the U.S. In those countries, it also takes more than a year longer for the medicines to become available and this can have significant impacts on patients. For example, in 2018, the Food and Drug Administration (FDA) and the European Medicines Agency (EMA) approved a new indication for LYNPARZA for ovarian cancer. However, the U.K.'s National Institute for Health and Care Excellence (NICE) has not recommended that the U.K.'s National Health System (NHS) reimburse for LYNPARZA in this indication, resulting in limited access for patients in the U.K. Instead of international reference pricing, we should focus on market-based solutions. We believe that there are several steps that lawmakers can take to ensure that drug prices are affordable for Americans, while ensuring that innovation in the biopharmaceutical sector can continue to flourish in the U.S. Our suggestions fall in five main categories, described in more detail below: Rebate Reform: The current pharmacy benefit manager (PBM) rebate system does not fully benefit patients and has resulted in a lack of transparency across the supply chain. We support the current proposed rule to eliminate rebates in Medicare Part D and Medicaid managed care. We also support efforts to eliminate rebates in the commercial sector as well, which will likely require legislation. We therefore recommend that Congress explore legislation that would eliminate rebates in the commercial market. Value-Based Agreements: As described in detail in our written testimony to the Senate Committee on Finance hearing, we are also working closely with payers and health systems to explore innovative solutions to improve access and affordability that demonstrate the value our medicines bring to patients and the health-care system. For several years, AstraZeneca has been exploring these types of solutions through value-based agreements where we are willing to work with health-care stakeholders to tie payment to patient outcomes. To date, we have entered into approximately 40 value-based agreements across our therapeutic areas with a variety of payers, making AstraZeneca a leader in the field of value-based agreements. We believe that there are steps the government can take to address certain regulatory challenges to the broader implementation of value-based agreements and help encourage the timely adoption of value-based agreements, including in public- sector programs like Medicare. To that end, AstraZeneca appreciates the support of Senators Warner and Cassidy for value-based agreements, as demonstrated by their requests for input on the Patient Affordability Value and Efficiency (PAVE) Act. This draft legislation would promote the development of value-based agreements by offering increased flexibility for manufacturers to enter into such arrangements, including with Medicare Part D plans. Biosimilars: We also encourage Congress to consider policies to encourage greater use of biosimilars in the U.S. We believe that competition is a key component to reducing costs, and that is why we support expanded use of biosimilars in the U.S. As a global company, we operate in countries, particularly those in the European Union, where biosimilar competition is particularly robust. We support a similarly vigorous biosimilars market in the U.S. We therefore appreciate the efforts of the FDA to increase the availability of biosimilars in the U.S., including the FDA's development of a Biosimilars Action Plan. We support efforts to streamline and improve the efficiency of the biosimilars approval pathway for the benefit of patients. Such efforts could include increased transparency into the patents applicable to biologic medicines. We also support cost-sharing and reimbursement policies that facilitate the uptake of biosimilars. Such policies include Medicare reimbursement rates that ensure that biosimilars can compete on equal footing with innovator medicines, and reductions to cost-sharing amounts for biosimilars. Out-of-Pocket Caps for Medicare Patients: In the commercial market, it is common for patients to have a cap on total out- of-pocket amounts. However, such a construct does not exist in the Medicare program. Because of the way the Part D benefit is designed, for example, cost-sharing can be particularly high in the first months of the plan year and/or in the first months of therapy. A recent study found that rates of prescription abandonment and delayed initiation of oral cancer therapies increase as cost-sharing amounts rise. Such a result reflects the need for a restructuring of the current benefit design, which could be accomplished by establishing a monthly or annual out-of-pocket cap. This would give patients greater certainty in the total amount of out-of-pocket costs they could face. Transparency: We support greater transparency across the biopharmaceutical supply chain, which includes greater transparency into drug pricing. To that end, we generally support the policies included in the current versions of the SPIKE and C-THRU Acts. There are a variety of State-level drug pricing transparency laws and regulations. We believe that having a consistent, Federal standard for drug pricing transparency requirements, like those included in the SPIKE Act, should pre-empt state transparency laws to reduce confusion and compliance burden. We also support transparency efforts to ensure that patients and prescribers have meaningful information on out-of-pocket costs at the point of prescribing, so that they can make informed decisions about the most appropriate and affordable therapy. foreign countries' pricing and reimbursement Question. President Trump and Secretary Azar have both repeatedly described their frustrations with ``foreign freeloading'' of U.S. drugs in the last year. ``When foreign governments extort unreasonably low prices from U.S. drug makers, Americans have to pay more to subsidize the enormous cost of research and development. . . . It's unfair and it's ridiculous, and it's not going to happen any longer.'' Do you agree that because of foreign countries' pricing and reimbursement systems, U.S. patients and innovators are shouldering the burden for financing edical advances? Answer. We agree that many foreign countries' pricing and reimbursement systems do not adequately recognize innovation in the biopharmaceutical sector. In many other countries, the government utilizes price controls for drug therapies, and in many cases these price controls result in reduced or delayed access to therapy for patients in those countries. The U.S. benefits from an open-market system that supports competition and innovation and accordingly Americans place high value on both choice and access to the latest medicines. For patients in the U.S., it is not a question of when an important treatment will be available, but rather how they will access that medicine. It is in this context that AstraZeneca continues to engage with other stakeholders regarding possible solutions and specific actions that can be taken to address pricing concerns, which we describe in greater detail in our written testimony. These approaches must balance the need to improve access and affordability while fostering innovation. Pricing controls as well as access and reimbursement practices in other countries are a challenge. Question. How do foreign countries' pricing and reimbursement systems affect our prescription drug costs? Answer. We do not take into account foreign market pricing in setting U.S. prices. Question. Are foreign governments taking note of the concerns being raised by the Trump administration and have they responded in any way? Answer. While these matters have been widely reported on globally, we do not have insights into actions being taken by other health authorities directly in response to the Trump administration's efforts in this area. Question. Has there been any noticeable change in any of our trade agreements since these concerns have been raised by the Trump administration? Answer. AstraZeneca and the biopharmaceutical industry have consistently advocated for trade agreements that support strong intellectual property rights and protect market access. We believe our trade partners should be fair and transparent so that patients around the world can benefit from U.S. innovation. medicaid closed formulary proposals Question. In an attempt to bring down drug costs, various States have been exploring whether to exclude certain drugs from its Medicaid program. For example, the State of Massachusetts recently asked CMS for permission to create a closed formulary where the State Medicaid program would pick at least one drug per therapeutic class. CMS denied their waiver request citing violation of Federal law, but this proposal does bring up important questions on how to contain drug prices in State Medicaid programs. If the principles of the Medicare Part D program--including the necessary patient protections--were applied to State Medicaid programs, do you think it [would] lower drugs costs while ensuring access to patients? Answer. Under the current construct in Medicaid, manufacturers provide mandatory rebates and in turn, States are required to cover all of the manufacturer's drugs. This ensures that Medicaid patients have access to the full range of available therapies. We support increased flexibility for State Medicaid agencies in managing their Medicaid programs, but only so long as there are robust protections that ensure that Medicaid patients can continue to access the medicines they need. medicaid ``best price'' Question. In the Trump administration's Blueprint, they suggested that because drug manufactures have to give Medicaid the ``best price'' on drugs, there is no incentive to offer deeper discounts to other payers--both government and commercial--than what is already offered under the Medicaid Drug Rebate Program. Does the Medicaid ``best price'' requirement encourage manufacturers to increase initial prices? Answer. We do not believe that the Medicaid Best Price requirement encourages manufacturers to increase their initial list price. However, the requirement does impact decisions regarding the size of rebates and discounts offered in the commercial sector because setting a new Best Price can result in significantly increased Medicaid rebate and 340B liability. Additionally, manufacturers may be hesitant to offer very aggressive value-based agreements due to the risk of setting a new Best Price. Question. What, if any, changes would you suggest we make to the program? Answer. We recommend an exemption from Best Price for value-based agreements, which is a policy included in Senator Grassley's and Senator Warner's draft version of the PAVE Act. outcomes-based contracts Question. In almost all of your testimonies, you highlight your support of outcomes-based contracts and how we need to be shifting our system toward that approach. How will these contracts lower drug costs for patients in both the near term and long-term? Answer. While most value-based agreements have been focused on securing patient access to our medicines and delivering better patient outcomes, where payers are willing, AstraZeneca is also looking to more directly address patient out-of- pocket affordability through these innovative arrangements. As an example, we recently announced the initiation of a value- based agreement for University of Pittsburgh Medical Center (UPMC) Medicare patients who are prescribed BRILINTA. This value-based contract, which was effective as of January 1, 2019, is groundbreaking in two ways. First, the contract lowers the out-of-pocket costs for a UPMC Medicare Part D patient to approximately $10 for a 30-day supply. Second, what UPMC pays for BRILINTA will vary based on patient outcomes, tying the cost of the medicine to its real-world clinical performance. We are currently exploring another value-based agreement in Medicare Part D. In addition to having a significant outcomes-based component, this arrangement would reduce patient out-of-pocket costs. This type of agreement allows patients to access their medicines at a lower out-of-pocket cost and payers to control their overall healthcare costs through paying for outcomes. Question. How will they lower overall health-care costs for our Federal programs? Answer. We believe medicines are part of the solution to controlling health-care costs. They not only improve patient outcomes and increase quality of life, but also reduce downstream costs. Value- based agreements have the potential to increase efficiencies in the health-care system, including government programs, by ensuring that payment is based on value rather than reimbursement based on volume. These agreements support patients receiving the most appropriate treatment, ensure appropriate patient behaviors and, most importantly, tie reimbursement to improved patient outcomes. In many cases value-based agreements encourage a focus on important patient behaviors such as adherence and persistence as well as improved emphasis on patient education to promote healthier lifestyles and choices. These agreements broaden payer focus to the total cost of care and quality outcomes. It is important that we look at all aspects related to the cost of care to find efficiencies that drive greater value in the health-care system. These opportunities exist in both the commercial and government sectors. We support value-based agreements because they allow us to reimburse the health-care system if our medicines do not deliver as intended. This solution demonstrates our willingness to stand behind the value of our medicines. Through the partnership of payers and policymakers, we look forward to a future where implementation of value-based agreements across public and private payers is widespread. Question. What have the preliminary results looked like so far? Answer. We are frequently asked if we have ever had to ``pay out'' on a value-based agreement, and the answer is ``yes.'' For example, we have entered into an agreement for one of our oncology medicines with a large payer. We have reimbursed the payer for more than 20 percent of patients on that medicine. Of course, we also have examples where we have seen the medicine perform as well or better than our clinical data. This is good for patients and good for the payer and health system overall in that, by providing access to that medicine, they have seen improved patient outcomes. transparency/point of sale Question. In almost all of your testimonies, you express your support for the Trump administration's proposal to allow manufacturers to provide PBMs up-front discounts that are passed onto patients at the point of sale. Do you feel like this proposal will make the transactions within the drug supply chain more transparent? Answer. Yes, the Trump administration's rebate proposal should make transactions more transparent because cost-sharing will reflect point- of-sale discounts and, therefore, net prices. We encourage the administration and Congress to closely assess the impact of such increased transparency on patients and the biopharmaceutical supply chain more broadly. Question. If so, would this transparency bring down drug costs-- overall and for specialty drugs? Answer. In general, we believe that increased transparency due to point-of-sale discounts will in turn lead to greater competition and reduced costs overall. However, the impact of transparency on the prices of specific drugs will vary based on the competitive landscape for that medicine. the relationship between wholesalers and manufacturers Question. When talking about the pharmaceutical supply chain, a lot of focus has been placed on the pharmacy benefit manager. But there's another side of the equation that I'd like to ask about. How do wholesalers negotiate pricing with manufacturers? Answer. In general, wholesalers do not negotiate pricing with manufacturers. Wholesalers receive service fees from manufacturers for bona fide services they provide. Question. What impact does this have on drug costs? Answer. In general, wholesalers do not negotiate pricing with manufacturers. Question. What incentives or disincentives do they have to contain price increases? Answer. Wholesalers receive service fees from manufacturers for bona fide services they provide. Certain fees across the supply chain-- including with wholesalers--are based on a percentage of the list price. We support efforts to ``de-link'' such fees from the list price across the supply chain, as this would align incentives across the supply chain to lower prices. ______ Questions Submitted by Hon. Ron Wyden proposed rebate rule Question. As has been done in many other settings, drug manufacturers said during the hearing that one reason list prices for drugs are high is that pharmaceutical benefit managers (PBMs) demand larger and larger rebates in order for the drug to receive favorable placement on a formulary. You and your colleagues who testified during the hearing stated if the administration's proposal on changes to the anti-kickback safe harbor for pharmaceutical rebates took effect, your company would likely lower list price. Like many Oregonians, I am skeptical drug manufacturers would voluntarily lower their prices. Therefore, would you support legislation that would (1) make similar changes the administration has put forward related to Part D and Medicaid managed care, (2) change the rebate system in a similar way to the proposal for the commercial market, and (3) require drug makers to lower the list price of their drugs equal to the amount of rebates provided today? Answer. Assuming the HHS rebate rule is finalized largely as proposed, AstraZeneca intends to comply with its requirements and use point-of-sale discounts. Our goal is to maintain net prices broadly in line with today, recognizing our ability to do so may be dependent on external factors and market response such as how plans evolve their benefit design and the total degree of transparency under the new model. AstraZeneca would plan to reduce list prices, pending reforms across all payers, including in the commercial sector in addition to Part D, as the current construct does not allow for two separate list prices (i.e., one list price for Part D and a different list price for the commercial sector). Therefore, we also support efforts to eliminate rebates in the commercial sector and recommend that Congress explore such legislation. While eliminating rebates is an important step, benefit designs must also be evaluated. medicaid drug rebate program Question. The Medicaid Drug Rebate Program (MDRP) requires manufacturers to provide a basic rebate and an additional inflationary rebate for both brand and generic drugs. The inflationary rebate is an increasingly substantial part of total rebates due in large part to large increases in drug prices that exceed inflation. Under current law, this inflationary rebate is capped at 100 percent of Average Manufacturer Price (AMP). This is the case even when manufacturers continue to raise their prices well above inflation. Please provide a list of all of your pharmaceutical products that have reached the Medicaid AMP rebate cap in any of the 20 quarters from January 1, 2014 through December 31, 2018. Answer. Please see Appendix B. Question. For each drug listed in response to question 1, please also provide a list of which quarters and years each drug hit the cap. Answer. Please see Appendix B. medicaid drug rebate program compliance Question. I am concerned about recent reports and legal settlements surrounding drug manufacturers' failure to comply fully with the requirements of the MDRP. For example, an analysis by the U.S. Department of Health and Human Services Office of Inspector General found that between 2012 and 2016 taxpayers may have overpaid by as much as $1.3 billion for 10 potentially misclassified drugs. That is why I introduced the Right Rebate Act with Chairman Grassley to prevent drug manufacturers from manipulating Medicaid to increase their profits. However, I continued to be concerned about oversight and manufacturer compliance with the requirements of the Medicaid Drug Rebate Program. Accordingly, please describe the following: Your company's current compliance plan and procedures used to ensure compliance with the requirements of the Medicaid Drug Rebate Program including internal audits or other checks you use to identify compliance vulnerabilities. Answer. All aspects of AstraZeneca's compliance with the requirements of the Medicaid Drug Rebate Program, including Statutory Pricing (average manufacturer price (AMP) and Best Price) and Medicaid Rebate payments, are covered by AstraZeneca's compliance framework. This compliance plan includes a robust review process, including Sarbanes-Oxley testing, self-auditing, and formal audits by internal and external audit. Question. Any past or ongoing issues of non-compliance. Answer. Since the implementation of AstraZeneca's compliance framework, we are not aware of any compliance issues that have been identified via this internal and external audit process. Question. Any corrective actions taken to address identified problems or issues of non-compliance with the MDRP and how such steps were communicated to the Centers for Medicare and Medicaid Services. Answer. As noted above, to date, no compliance issues have been identified via this internal and external audit process. Question. Any steps taken to improve compliance and ensure that all Medicaid drug rebates owed to the Federal Government and the States are paid in full. Answer. AstraZeneca has a comprehensive compliance framework that includes Sarbanes-Oxley testing, self-auditing, and formal audits by internal and external audit. Additionally, as it relates to Medicaid drug rebates owed to the Federal Government and States, AstraZeneca performs additional reviews of claims-level data, ensuring the completeness and accuracy of both the payments made by manufacturers as well as claims submitted to manufacturers. This process has identified duplicate pharmacy claims submitted to State Medicaid Agencies resulting in overpayment by both States and manufacturers. Clearly, these overpayments disadvantage both the States and manufacturers like AstraZeneca. bonus payments tied to specific drugs Question. I am concerned by the potential for employee financial incentives to encourage high launch prices and price increases for prescription drugs. Is your salary, bonus, or other compensation tied to sales or revenue targets of a single product your company sells? Has it ever been? If yes, please state the product or products to which your salary, bonus or other compensation was tied. Answer. The CEO's compensation as well as the compensation of other senior leaders is directly based on three areas of performance that are generally weighted equally: development and delivery of innovative science, our aggregate sales, and other important financial metrics. AstraZeneca understands that executive pay is a closely scrutinized issue. As part of our compensation decisions, we are mindful of the sensitivity of this issue as we determine how best to incentivize, reward and retain executives capable of leading a global pharmaceutical company in a highly competitive market. Question. Is your salary, bonus, or other compensation tied to either revenue or net income of the company as a whole? Has it ever been? If yes, please explain what assumptions about price increases are used when the compensation committee sets revenue or net income goals. Does the compensation committee provide any guidance to executives in regards to the amount of revenue that the company will generate from price increases versus volume growth? Answer. The CEO's compensation as well as the compensation of other senior leaders is directly based on three areas of performance that are generally weighted equally: development and delivery of innovative science, our aggregate sales, and other important financial metrics. AstraZeneca's Remuneration Committee does not provide any guidance on price increases. provision of rebates in exchange for formulary placement Question. In today's system, drug makers receive a limited time window to sell their drug without competition. After that period has expired, low-cost generics should become available. However, drug makers often prevent access to these cheaper generic drugs in Medicare. Researchers have found that 72 percent of Medicare Part D plans charged lower cost-sharing for a brand name drug compared to its generic equivalent. This means seniors were charged less out of pocket for brand name drugs compared to generics that are on average four times cheaper than the brand-named drug. This happens because drug makers pay a rebate to the Part D plans in order to give the more expensive drug better treatment than a generic. As a result, Medicare spending increases due to the current structure of the Part D benefit. Has your company ever paid a rebate to a Part D plan so that a brand name drug would get preferential treatment (i.e., lower cost- sharing or less utilization management) compared to a cheaper generic? Answer. In certain instances, AstraZeneca enters into arrangements under which a branded agent is discounted at or below the net cost of the generic(s) in the market, therefore benefiting the plan and the beneficiary. AstraZeneca typically enters into these types of arrangements for medicines already existing on formulary. These arrangements benefit patients by ensuring greater affordability for the branded medicine and by ensuring continuity of treatment if a patient has already been prescribed a branded medicine. These arrangements also support competition because they provide the opportunity for multiple competitors and medicine options to compete on price and other factors. We have had several such arrangements in Medicare Part D (see Appendix C). Question. If so, please provide: A list of the drugs for which your company has done this since January 1, 2014. Answer. A list providing this information is attached as Appendix C. Question. The number of Part D plans in which this type of rebate was given for each drug in each year. Answer. A list of the relevant Part D plans is included in Appendix C. net prices Question. During your testimony, you stated, ``The estimates for 2018 show that across our medicines, our average rebate is nearly 50 percent of our gross revenues in the U.S. Despite this, in recent years, in our primary cap portfolio, we have seen flat to declining net effective prices for most of our medicines.'' Please describe how the company's year-over-year aggregate net price is calculated. Answer. The analysis discussed during the hearing on February 26, 2019 was completed by brand; the change in Net Price was calculated at the brand level, and then weighted based on Net Sales for each brand as a percent of Total Net Product Sales for 2018.\2\ --------------------------------------------------------------------------- \2\ Net Product Sales reflect the invoiced amount less movements in estimated accruals for rebates and chargebacks given to managed-care and other customers. Cash discounts for prompt payment are also deducted from sales. Average Net Price per Unit excludes product returns, and the figures were arrived at using the conventional Net Price calculation, that is, before deducting cost of goods sold, royalties, and variable selling expenses. --------------------------------------------------------------------------- Question. Please also specifically address the following questions: How many products are included in the calculation of the average net price change? What was the median net price change? Answer. The analysis discussed during the hearing on February 26, 2019 included 26 brands that represent 98 percent of annual Net Product Sales in the United States for the period ending December 31, 2018. The Median Price Change (prior to weighting) was a Net Price decrease of 1 percent. Question. Is net price weighted? If so, how? For example, in determining the aggregate net price does the company assign different weights to different products based on volume or other factors? Are ``on patent'' and ``off patent'' drugs weighted identically? Are other statistical weights used or are all products treated equally? Answer. The analysis discussed during the hearing on February 26, 2019 was completed by brand; the change in Net Price was calculated at the brand level, and then weighted based on Net Sales for each brand as a percent of Total Net Product Sales for 2018 irrespective of whether the medicines are on or off patent. Question. Does the figure that you provided during your testimony account for U.S. prices, international prices, or both? Generally speaking, when your company reports net price changes, does it differentiate between U.S. and international prices? Answer. The analysis discussed during the hearing on February 26, 2019 referred to 26 brands that represent 98 percent of annual Net Product Sales in the United States for the period ending December 31, 2018. Question. Please list the five drugs your company sold in the U.S. that had the greatest year-over-year net price increase in 2018, noting the increase for each drug by dollar figure and percentage. Please list the five drugs your company sold in the U.S. that had the lowest year- over-year net price increase (and/or the greatest decrease) in 2018, noting the increase (or decrease) for each drug by dollar figure and percentage. Answer. In 2018, we experienced a Weighted Average Net price decline in our hyper-competitive respiratory and diabetes therapeutic areas, with declines of 2.4 percent and 1.9 percent, respectively. Our Weighted Average Net prices in oncology remained flat. Brand-specific pricing information is competitively sensitive information. Question. For 2018, what was the average net price change in the U.S. market for (1) drugs with no competition, (2) drugs with only branded competition, and (3) drugs with generic competition? Answer. For 2018, the Weighted Average Net price change in the United States market for: Medicines with no competition was an increase of 0.6 percent; Branded ``on patent'' medicines without generic equivalents was a decrease of 4.7 percent; ``Off patent'' medicines with generic equivalent competition was an increase of 4.6 percent. With respect to the last category of medicines described above, we note by way of context that once generic options enter the market, our market share rapidly erodes, as many PBMs, insurers, and government agencies to which AstraZeneca offers rebates and discounts replace our branded medicines on their formularies with these generic competitors. Accordingly, the mix of business for medicines with generic competition shifts towards programs whereby health plans/PBMs chose to list our branded medicines on their formularies given a lower net cost versus generics, and to individual patients who chose to pay for branded agents over generic agents, resulting in a higher average net effective price across all distribution channels. Question. You state that ``the estimates for 2018 show that across our medicines, our average rebate is nearly 50 percent of our gross revenues in the U.S.'' For each product, please disclose the gross revenue and the amount of rebates paid. Answer. The table below reflects our Product Sales in the U.S. for the period ending December 31, 2018, including the proportion of Gross Sales allocated to estimated amounts we expect to pay to third-party managed care organizations, hospitals, long-term care facilities, group purchasing organizations, and various Federal or State programs. The percentage of Gross Product Sales column reflects our effective rebate rate per channel, a combination of mix of business in that channel and related rebate rate. ------------------------------------------------------------------------ USD (in % of Gross millions) Product Sales ------------------------------------------------------------------------ Gross Product Sales $16,538,000 ------------------------------------------------------------------------ Chargebacks $(2,224,000) -13% ------------------------------------------------------------------------ Regulatory--Medicaid and State $(1,304,000) -8% programs ------------------------------------------------------------------------ Contractual--Managed-care and $(4,600,000) -28% Medicare ------------------------------------------------------------------------ Cash and other discounts $(286,000) -2% ------------------------------------------------------------------------ Customer returns $(119,000) -1% ------------------------------------------------------------------------ U.S. Branded Pharmaceutical Fee $(140,000) -1% ------------------------------------------------------------------------ Other $(989,000) -6% ------------------------------------------------------------------------ Net Product Sales $6,876,000 ------------------------------------------------------------------------ Brand-specific pricing information is competitively sensitive information. ______ Questions Submitted by Hon. Robert Menendez Question. During the hearing, when I asked whether your company engaged in tactics to delay generic production of your products, you answered ``no.'' However, AstraZeneca appears on the FDA's list of companies who have access complaints against them. Can you explain the discrepancy between your answer and the FDA list? The FDA list can be found here: https://www.fda.gov/Drugs/ DevelopmentApprovalProcess/HowDrugsareDevelopedandApproved/ ApprovalApplications/AbbreviatedNewDrug ApplicationANDAGenerics/ucm607738.htm. Answer. AstraZeneca appreciates the opportunity to address the question of one of our medicines (BRILINTA) appearing on the Reference Listed Drug Access Inquiries list (RLD List). We would first like to state that AstraZeneca supports allowing generic manufacturers access to samples. Withholding or otherwise blocking such access is inconsistent with that position. Our internal review has not identified any unanswered, delayed, or outstanding requests for samples of BRILINTA (ticagrelor) by any generic manufacturers. It is our understanding that BRILINTA was included on the RLD List based on a single inquiry received by the FDA. Unfortunately, the RLD List does not identify the company that reportedly requested information (or samples) from AstraZeneca, the date the information was requested, or any other information that would allow AstraZeneca to better understand or further investigate the circumstances of this inquiry. On its website, the FDA does advise that it has ``not independently investigated or confirmed the access limitations described in the inquiries received.'' Given this limitation, the listing of an inquiry on the RLD List does not mean that the FDA has in fact determined that access to samples by generic manufacturers was limited or withheld for the medicines identified. Indeed, based on our internal review, we have not identified any circumstances that substantiate the inquiry received by the FDA relating to BRILINTA. BRILINTA is and has always been available via normal commercial distribution channels (i.e., wholesalers) since its U.S. launch. It has never had a restricted distribution program. Finally, more than 15 generic manufacturers have applied for regulatory approval from the FDA for the manufacture of generic ticagrelor and some, like Watson/Teva, have received tentative approvals from the FDA. Because conducting bioequivalence studies with the branded medicine is an FDA preapproval requirement, it is clear that these generic manufacturers are not having difficulty accessing branded ticagrelor for their studies. In light of the context provided above, it is unclear why any generic manufacturer would be unable to obtain a sample of BRILINTA for their purposes or why an inquiry was lodged with the FDA related to this medicine. Question. When new products enter the market, do drug companies set high initial rebates and then provide deep rebates in order to gain access to insurance plan's formularies? Answer. No, this is not AstraZeneca's general practice. We negotiate rebates and discounts with payers and pharmacy benefit managers (PBMs)--including in Medicare Part D--to help ensure that patients have the most robust access possible to our therapies. Without these discounts and rebates, many lifesaving medicines would not be placed on plan formularies and therefore would be largely unavailable to the patients who need them most. The current rebate system creates misaligned incentives. This results in a growing differential between list and net prices. We support reforms of this system that include the elimination of rebates in the commercial sector and in Medicare Part D, which will result in the reduction of the differential between list and net prices and which would allow manufacturers to ensure that the initial list price of a drug reflects its net value. Question. If CMS finalizes the rebate rule, do you anticipate future products entering the market with significantly lower initial list prices? Answer. We believe that eliminating rebates across Medicare Part D and commercial will generally result in lower initial list prices than in the absence of reform, although the impact on specific medicines will vary based on the competitive dynamics for that medicine. Reform only in Part D and not commercial is unlikely to impact initial list price setting practices, as the current structure does not allow for two separate list prices (i.e., one list price for Part D and a different list price for the commercial sector). ______ Questions Submitted by Hon. Thomas R. Carper Question. What are your recommendations for lowering prices for the 40 percent of drugs that do not offer rebates in Medicare Part D? In the health insurance plans that you offer your employees, do you ask your insurers to pass through the full manufacturer rebates to the beneficiaries? Answer. All of our medicines are rebated under the statutory requirements of Medicaid, Federal Supply Schedule, 340B, and the Part D coverage gap discount program. For our highly innovative, targeted therapies, we do not typically provide additional rebates other than through our value-based agreements, where such discounts are based on patient outcomes. In general, medicines with minimal rebates are the newest and most innovative on the market. Expanded use of value-based agreements is a key component to lowering costs and improving access to these medicines that are currently not in highly rebated therapeutic classes. Under such arrangements, manufacturers may contract to reimburse plans if the medicine does not work as expected, lowering risks for the payer. This also results in competition across manufacturers of medicines in these classes by facilitating competition across clinical results and outcomes. As we stated before the Senate Committee on Finance, AstraZeneca has put forward several proposals in addition to value-based agreements to address drug pricing: Moving away from the current rebate system, while continuing to work with payers and PBMs to ensure robust negotiations; Using a portion of discounts and rebates to create out-of- pocket caps for Medicare patients; Encouraging biosimilars and eliminating policy and commercial barriers to their greater use. AstraZeneca also supports increased transparency across the biopharmaceutical supply chain, including transparency with respect to drug pricing. To that end, we generally support the policies included in the current versions of the SPIKE and C-THRU Acts. There are a variety of state-level drug pricing transparency laws and regulations. We believe that having a consistent, federal standard for drug pricing transparency requirements, like those included in the SPIKE Act, should pre-empt state level laws to reduce confusion and compliance burden. We also support transparency efforts to ensure that patients and prescribers have meaningful information on out-of-pocket costs at the point of prescribing, so that they can make informed decisions about the most appropriate and affordable therapy. AstraZeneca wants to be a constructive partner in identifying solutions that continue to allow manufacturers to innovate while creating a more efficient and more affordable system. AstraZeneca provides generous health-care benefits to its employees. Today, we provide a point-of-sale discount on prescription medicines in the form of low out-of-pocket costs for our employees. We cap our employees' out-of-pocket costs on prescription medicines at $50 per fill to ensure they do not forgo their prescriptions due to high out-of-pocket costs. Question. The systems for pricing and distributing drugs are opaque and difficult to understand. What are your recommendations for increasing transparency in how your companies set the list prices for drugs, and for improving transparency in the supply chain for prescription drugs? Would you support Federal standards for transparency in setting the list prices for drugs? Answer. We do believe that greater transparency is needed for manufacturers as well as other entities in the supply chain. We therefore would generally support transparency requirements such as those included in the SPIKE and C-THRU Acts. Any transparency requirements should consider the need to protect competitively sensitive information to ensure robust competition in the market. There are a variety of State-level drug pricing transparency laws and regulations. We believe that having a consistent, Federal standard for drug pricing transparency requirements, like those included in the SPIKE Act, should pre-empt State-level laws to reduce confusion and compliance burden. Question. In nearly every sector of the health-care industry, Medicare, Medicaid, employers, and insurers are moving away from fee- for-service payments to reimbursements based on value and performance. Prescription drugs and medical devices were the glaring exceptions to this trend until recently. How many of your drugs are included in value-based contracts and how many patients are benefiting from them? How do these value-based contracts work to lower drug prices for both patients and taxpayers? Answer. We believe medicines are part of the solution to controlling health-care costs. They not only improve patient outcomes and increase quality of life, but also reduce downstream costs. Value- based agreements allow us to reimburse the health-care system if our medicines do not deliver as intended. This solution demonstrates our willingness to stand behind the value of our medicines. AstraZeneca is working closely with payers and health systems to explore innovative solutions to improve access and affordability that demonstrate the value our medicines bring to patients and the health- care system. Our value-based agreements aim to manage the totality of treatment costs and keep people healthy and out of the hospital. For several years, AstraZeneca has been exploring these types of solutions through value-based agreements where we are willing to work with health-care stakeholders to tie payment to patient outcomes. To date, we have entered into approximately 40 value-based agreements for 15 medicines across our therapeutic areas with a variety of payers, making AstraZeneca a leader in the field of value-based agreements. Tens of thousands of patients have benefited from improved access as part of these agreements. As an example, and as noted in our written testimony submitted to the Senate Committee on Finance, AstraZeneca agreed with Express Scripts that for IRESSA, an oral treatment for certain types of lung cancer, we will fully reimburse Express Scripts for discontinued use before the third fill, including if discontinuation occurs because patients did not respond to treatment. While most of these agreements have been focused on securing patient access to our medicines and delivering better patient outcomes, where payers are willing, we are also looking to more directly address patient out-ofpocket affordability through these innovative arrangements. As an example, we recently announced the initiation of a value- based agreement for University of Pittsburgh Medical Center (UPMC) Medicare patients who are prescribed BRILINTA. This value-based contract, which was effective as of January 1, 2019, is groundbreaking in two ways. First, the contract lowers the out-of-pocket costs for a UPMC Medicare Part D patient to approximately $10 for a 30-day supply. Second, what UPMC pays for BRILINTA will vary based on patient outcomes, tying the cost of the medicine to its real-world clinical performance. We are currently exploring another value-based agreement in Medicare Part D. In addition to having a significant outcomes-based component, this arrangement would reduce patient out-of-pocket costs. This type of agreement allows patients to access their medicines at a lower out-of-pocket cost and payers to control their overall health- care costs through paying for outcomes. Question. Last year, Senator Portman and I did an investigation on the pricing of an opioid overdose reversal drug called EVZIO, manufactured by Kaleo. Kaleo increased the price of EVZIO from $575 in 2014 to $4,100 in 2017. We found that the best price Medicare was able to get for EVZIO, about $4,000, was much higher than the price other federal programs and private insurers were able to get. It seemed that Kaleo was able to get this higher price of $4,000 from Medicare by helping doctors fill out paperwork showing that the drug was medically necessary, even though there are cheaper alternatives on the market. As a result of the investigation, Kaleo announced it will bring a generic version of the drug to market at only $168 per pack. Are any of your companies providing medical necessity paperwork to doctors in order to get your drugs covered by Medicare? Answer. AstraZeneca policies prohibit completing medical necessity paperwork for doctors or their staff as described in your inquiry. Question. In 2017, the Rand Corporation estimated that biosimilar drugs, which are competitors to complex, biologic drugs, could save the United States more than $50 billion over the next decade. Some of you have also argued that increasing the use of biosimilar drugs would help lower drugs costs for consumers and taxpayers. What is delaying the uptake of biosimilar drugs in the United States? What policies do you recommend to increase the development of biosimilar drugs? Answer. AstraZeneca believes that competition is a key component to reducing costs, and that is why we support the expanded use of biosimilars in the U.S. As a global company, we operate in countries, particularly those in the European Union, where biosimilar competition is particularly robust. We support a similarly vigorous biosimilars market in the U.S. There are several challenges to biosimilar uptake in the U.S., including contracting and rebating dynamics and difficulty in obtaining interchangeability status. We therefore appreciate the efforts of the FDA to increase the availability of biosimilars in the U.S., including the FDA's development of a Biosimilars Action Plan. We support efforts to streamline and improve the efficiency of the biosimilars approval pathway for the benefit of patients. Such efforts could include increased transparency into the patents applicable to biologic medicines. We also support reimbursement policies that facilitate the uptake of biosimilars. Such policies include Medicare reimbursement rates that ensure that biosimilars can compete on equal footing with innovator medicines, and reductions to cost-sharing amounts for biosimilars. We also believe the elimination of rebates will help biosimilars compete with innovator medicines. ______ Questions Submitted by Hon. Benjamin L. Cardin Question. The United States is one of the only countries in the world to allow prescription drug manufacturers to advertise directly to consumers through magazines, billboards, radio, and television commercials. While I will not argue that it is beneficial to educate consumers about an unfamiliar disease and encourage them to seek medical help, most commercials from all of your companies recommend asking about a specific brand name drug, not a medical condition. Furthermore, even if your advertisements follow all FDA rules and list medication side effects, they also almost always list these while a smiling, apparently healthy person is walking on a beach. Researchers say that this type of imagery, combined with viewing hours of drug commercials each month, leads consumers to underestimate the risks associated with medications. For the past decade, studies have shown that aggressive direct-to-consumer advertising is associated with rising drug prices and an increase in inappropriate drug prescriptions. Since researchers have concluded that consumers are misunderstanding the benefits and risks described in your ads, what further policies could help you and your colleagues ensure that you are educating patients in a clear manner? Answer. Our advertising complies with regulatory requirements governing direct-toconsumer (DTC) advertising and AstraZeneca believes that DTC advertising is important to raising brand and disease awareness, fostering patient education, and enhancing the dialogue between patients and their physicians. Unfortunately, these positive impacts of health-care communication efforts are often left out of the DTC debate. pharmaceutical companies continue to raise prices Question. As you are well aware, high prescription drug prices are the number one concern for Americans and their families. According to the Organization for Economic Cooperation and Development, the average American spends around $1,208 annually on prescription drugs. There have been several instances where brand name or even generic drugs that have been on the market for years continue to increase in price. One of the most well-known examples is Mylan's increase of the price of EpiPen from less than $100 in 2007 to more than $600 in 2016. Another example, is the ever-increasing price of insulin. Sanofi increased the price of a vial of Lantus from $88.20 in 2007 to $307.20 in 2017. And those are just a small sample of price increases. Why don't we see price decreases for drugs that have been on the market for years without new formulations or added benefit? Answer. As an initial matter, it is important to note the distinction between list and net prices. Over the past several years, discounts and rebates for our therapies have increased overall, both in the commercial sector and Part D. In recent years, in our primary care portfolio, which includes the majority of our therapies, we have seen flat to declining net effective prices to AstraZeneca for most of our medicines. Flat to declining net prices is a trend across the industry. However, the current system makes list price decreases challenging. Therefore, to accomplish meaningful change in terms of lowering list price, the system must be restructured to eliminate rebates. Assuming the HHS rebate rule is finalized largely as proposed, AstraZeneca intends to comply with its requirements and use point-of- sale discounts. Our goal is to maintain net prices broadly in line with today, recognizing our ability to do so may be dependent on external factors and market response such as how plans evolve their benefit design and the total degree of transparency under the new model. AstraZeneca would plan to reduce list prices, pending reforms across all payers, including in the commercial sector in addition to Part D, as the current construct does not allow for two separate list prices (i.e., one list price for Part D and a different list price for the commercial sector). Therefore, we also support efforts to eliminate rebates in the commercial sector, and recommend that Congress explore such legislation. While eliminating rebates is an important step, benefit designs must also be evaluated. pay for delay Question. Pay for delay is a tactic that more and more branded drug manufacturers have been using to stifle competition from lower-cost generic manufacturers. This allows you to sidestep competition by offering patent settlements that pay generic companies not to bring lower-cost alternatives to market. These ``pay-for-delay'' patent settlements benefit both brand-name pharmaceutical companies by helping them avoid costly patent litigation and general manufacturers by rewarding them a hefty sum to delay entering the market with a cheaper drug alternative. However, these deals do not benefit consumers. According to an FTC study, these anticompetitive deals cost consumers and taxpayers $3.5 billion in higher drug costs every year. Does your company partake in pay-for-delay settlements? Answer. AstraZeneca does not enter into settlements that pay generic competitors to delay entry into the market. In the absence of a settlement, a generic would not necessarily prevail in the patent litigation and therefore would not be able to enter the market. Indeed, AstraZeneca has entered into many early-entry patent settlements that permit generic competitors to enter the market before expiration of AstraZeneca's patent rights by allowing generic manufacturers to license innovator patents. All of AstraZeneca's patent settlements fully comply with the law. These settlements provide increased clarity and stability to both parties, allowing innovators like AstraZeneca to continue investing substantially in new medicines for patients and frequently allowing generic competitors to enter the market before expiration of AstraZeneca's patent rights. Question. Why would a pharmaceutical company enter into a pay-for- delay agreement? Answer. AstraZeneca does not enter into agreements that pay generic competitors to delay entry into the market. Question. Do you think these agreements stifle competition and prevent generic alternatives to your branded medications? Answer. AstraZeneca does not enter into agreements that pay generic competitors to delay entry into the market. However, AstraZeneca has entered into many early-entry patent settlements that permit generic competitors to enter the market before expiration of AstraZeneca's patent rights by allowing generic manufacturers to license innovator patents. These do not stifle competition but instead permit early entry by resolving patent disputes that would otherwise prevent generic alternatives to branded medication. value-based pricing Question. One idea I wanted to get your thoughts on today, is the idea of value-based pricing. This is an idea where a company could link the single price it charges for a given drug to an assessment of how well it works. Some value-based pricing arrangements could allow insurers and patients to receive rebates from drug manufacturers if a drug failed to work (outcome-based pricing). Another version would involve ``indication-based pricing'' in which drug companies charge different prices for the same drug when it is used to treat different conditions. Dr. Soriot, we have heard that AstraZeneca has been participating in a value-based program in collaboration with the University of Pittsburgh Medical Center. Could you talk more about your research in value-based pricing and how you believe this could be possible solution to some of the high drug prices? Answer. We believe medicines are part of the solution to controlling health-care costs. They not only improve patient outcomes and increase quality of life, but also reduce downstream costs. Value- based agreements allow us to reimburse the health-care system if our medicines do not deliver as intended. This solution demonstrates our willingness to stand behind the value of our medicines. AstraZeneca is working closely with payers and health systems to explore innovative solutions to improve access and affordability that demonstrate the value our medicines bring to patients and the health- care system. Our value-based agreements aim to manage the totality of treatment costs and keep people healthy and out of the hospital. For several years, AstraZeneca has been exploring these types of solutions through value-based agreements where we are willing to work with health-care stakeholders to tie payment to patient outcomes. To date, we have entered into approximately 40 value-based agreements across our therapeutic areas with a variety of payers. Our research in value-based agreements has been focused on addressing the comprehensive value of a medicine in terms of medical cost offsets and the economic impact of achieving certain health benefits with a medicine in a specific population. Our experience in this area consists of health economics and outcomes research (HEOR) and real-world evidence (RWE) studies which correlate improved outcomes and overall better health to a direct, positive economic impact, realized by both the payer and the patient. We use HEOR and RWE data to establish the metrics of the value-based agreement. Another important part of our value-based agreement research is how we measure the impact of a value-based agreement, so we can learn what works and what does not work for future iterations of value-based agreements. In addition, by aligning payments for medicines more directly with their value in improving health outcomes and/or reducing the need for other healthcare services (such as hospitalizations), value-based arrangements make pharmaceutical manufacturers accountable for the results our medicines achieve and can help improve patients' health and maximize the benefits of healthcare spending. Over time, proliferation of value-based agreements can shift utilization toward medicines with greater clinical value and greater ability to reduce hospitalizations and other costly services, resulting in better health outcomes and lower overall healthcare spending. As manufacturers develop more complex, personalized, and promising treatments--such as gene therapies, cell therapies, or immuno- therapies--it will be increasingly important for health plans to enter into value-based agreements so that they and our healthcare system may recognize the full value of those treatments and make them available to patients at affordable out-of-pocket amounts. Value-based agreements serve an important role in linking the price of a medicine to beneficiaries' demonstrated real world outcomes using that medicine. While most of these agreements have been focused on securing patient access to our medicines, some have also helped payers identify which patient types are most likely to benefit from our medicines and deliver improved patient outcomes. Partnering to drive this type of clarity can reduce overall drug spend in meaningful ways. Where payers are willing, we are also looking to more directly address patient out- of-pocket affordability through these innovative arrangements. As you mention, we recently announced the initiation of a value- based agreement for University of Pittsburgh Medical Center (UPMC) Medicare patients who are prescribed BRILINTA. This value-based contract, which was effective as of January 1, 2019, is groundbreaking in two ways. First, the contract lowers the out-of-pocket costs for a UPMC Medicare Part D patient to approximately $10 for a 30-day supply. Second, what UPMC pays for BRILINTA will vary based on patient outcomes, tying the cost of the medicine to its real-world clinical performance. Through the partnership of payers and policymakers, we look forward to a future where implementation of value-based agreements across public and private payers is widespread. Value-based agreements are one proactive solution; they are not the only solution. drug rebate rule Question. In January, the Department of Health and Human Services' (HHS) Office of Inspector General (OIG) promulgated a new regulation to remove regulatory safe harbor protections under the Anti-Kickback Statute (AKS) for rebates on prescription drugs rebates paid by manufactures to PBMs under Medicare Part D and for Medicaid managed care organizations (MCOs). The OIG proposal attempts to ban most rebates by eliminating their regulatory protections. The rule is predicted to increase net drug costs in its early years. The CMS actuaries estimate it would cost $196 billion over 10 years. Despite this high price tag, the beneficiary benefits are limited. The proposed rule notes that under the CMS Actuary's analysis, the majority of beneficiaries would see an increase in their total out-of-pocket payments and premium costs; reductions in total cost sharing will exceed total premium increases. I wanted to ask a question about the administration's rebate rule, which I understand that many of the drug manufacturers, and your main trade association, strongly support. According to an analysis of the rule by the Office of Actuaries at CMS, drug manufacturers are likely to initially retain 15 percent of the current rebates as higher net drug prices. Given that estimate, can you provide the committee with any assurances that prices will not increase under this proposed rule? Answer. Assuming the HHS rebate rule is finalized largely as proposed, AstraZeneca intends to comply with its requirements and use point-of-sale discounts. Our goal is to maintain net prices broadly in line with today, recognizing our ability to do so may be dependent on external factors and market response such as how plans evolve their benefit design and the total degree of transparency under the new model. AstraZeneca would plan to reduce list prices, pending reforms across all payers, including in the commercial sector in addition to Part D, as the current construct does not allow for two separate list prices (i.e., one list price for Part D and a different list price for the commercial sector). Therefore, we also support efforts to eliminate rebates in the commercial sector, and recommend that Congress explore such legislation. While eliminating rebates is an important step, benefit designs must also be evaluated. ______ Questions Submitted by Hon. Sherrod Brown Question. According to an article recently published in the Journal of the American Medical Association, medical marketers spent nearly $30 billion dollars in 2016, up from $17 billion in 1997. Direct-to- Consumer (DTC) advertising had the biggest percentage increase: from $2.1 billion, or 11.9 percent of all medical marketing, in 1997 to $9.6 billion, or 32 percent of total spending, in 2016. Can you please provide what your ratio of spending on sales and marketing to research and development is today? Answer. In 2018, we spent $5.9 billion on RandD and $6.1 billion on Sales and Marketing, globally. Our Sales and Marketing figures include all costs incurred in selling, marketing, promoting, and distributing our products. price-gouging Question. Sanofi, as I understand it, has made a pledge to the public to limit its price increases to the national health expenditures growth projection. Would your company commit to a cap on annual price increases as part of your PhRMA membership criteria? Answer. Our decisions around pricing would always need to remain independent of PhRMA membership criteria. Question. What policies would you propose to help ensure lower launch prices for new drugs? Answer. As we stated at the Senate Committee on Finance hearing, AstraZeneca has put forward a number of proposals to address drug pricing, including: Moving away from the current rebate system, while continuing to work with payers and PBMs to ensure robust negotiations; and Encouraging biosimilars and eliminating policy and commercial barriers to their greater use. As described below, we also support efforts to increase transparency in the biopharmaceutical supply chain and drug pricing specifically. transparency Question. In many of your testimonies, you mentioned that the current system of pharmacy benefit manager (PBM) back-end rebates do not rarely results in a scenario where the PBM passes on savings to consumers at the point of sale (POS). The administration recently proposed a rule to eliminate the anti-kickback statute safe harbor protections for these drug rebates. Do you agree that greater transparency should be required to understand how manufacturers and PBMs are negotiating prices and rebates to ensure that savings are passed down to beneficiaries? Answer. Yes, AstraZeneca agrees that greater transparency is needed. We therefore generally support the policies included in the current versions of the SPIKE and C-THRU Acts. There are a variety of State-level drug pricing transparency laws and regulations. We believe that having a consistent, federal standard for drug pricing transparency requirements, like those included in the SPIKE Act, should pre-empt state level laws to reduce confusion and compliance burden. pbms Question. An Axios article from March 7, 2019 highlights the fact that, while ``pharmaceutical companies put a lot of the blame for high drug prices on pharmacy benefit managers,'' many large pharmaceutical companies ``rely on PBMs to manage their own health-care benefits.'' In your role as an employer, does your company contract with a pharmaceutical benefit manager (PBM) to administer the prescription drug benefits for your employees and negotiate lower drug costs on your behalf? Answer. AstraZeneca prescription drug benefits are managed by Express Scripts. Question. For those of you who do use a PBM to help manage the prescription drug benefit for your employees, how do you utilize the rebates your PBM negotiates to lower health-care costs or drug costs for your employee plans and what does your company do with that savings? Specifically, do the savings go toward lowing premiums? Answer. AstraZeneca provides generous healthcare benefits to its employees. Today, we provide a point-of-sale discount on prescription medicines in the form of low out-of-pocket costs for our employees. We cap our employees' out-of-pocket costs on prescription medicines at $50 per fill to ensure they do not forgo their prescriptions due to high out-ofpocket costs. Question. For those of you who do use a PBM to help manage the prescription drug benefit for your employees, does your PBM offer point-of-sale rebates to your employees? Answer. While AstraZeneca does not currently offer point-of-sale rebates to employees, we are exploring opportunities to evolve our benefits in the future. ______ Questions Submitted by Hon. Sheldon Whitehouse Question. Please describe any policy changes you support that would result in your company lowering the list prices of its drugs. Answer. The current rebate construct is the key challenge in reducing list prices and we would support legislation that would eliminate rebates in Part D and the commercial sector. Assuming the HHS rebate rule is finalized largely as proposed, AstraZeneca intends to comply with its requirements and use point-of-sale discounts. Our goal is to maintain net prices broadly in line with today, recognizing our ability to do so may be dependent on external factors and market response such as how plans evolve their benefit design and the total degree of transparency under the new model. AstraZeneca would plan to reduce list prices, pending reforms across all payers, including in the commercial sector in addition to Part D, as the current construct does not allow for two separate list prices (i.e., one list price for Part D and a different list price for the commercial sector). Therefore, we also support efforts to eliminate rebates in the commercial sector, and recommend that Congress explore such legislation. While eliminating rebates is an important step, benefit designs must also be evaluated. Question. How much does your company's research and development portfolio rely on taxpayer-funded research conducted by the National Institutes of Health (NIH)? How many of your company's products are based, at least in part, on NIH research, and how many are the result of research funded solely by your company? Answer. We collaborate with the National Institutes of Health and the National Cancer Institute, and these partnerships can lead to important advances for patients. However, biopharmaceutical companies conduct the vast majority of R&D needed to bring new medicines to patients and they bear the associated costs and risks. Question. In each of the last 5 years, how much has your company spent on research and development versus the advertising and marketing of your products? Answer. Last year alone, we invested nearly $6 billion in R&D, which represents 28 percent of our total product sales, well above the industry average. Our Sales and Marketing figures include all costs incurred in selling, marketing, promoting, and distributing our products. ------------------------------------------------------------------------ Year R&D Investment Sales and Marketing ------------------------------------------------------------------------ 2018 $5.9 billion $6.1 billion ------------------------------------------------------------------------ 2017 $5.8 billion $5.6 billion ------------------------------------------------------------------------ 2016 $5.9 billion $5.8 billion ------------------------------------------------------------------------ 2015 $6.0 billion $6.6 billion ------------------------------------------------------------------------ 2014 $5.6 billion $7.1 billion ------------------------------------------------------------------------ Question. During the hearing, you mentioned that your company would be likely to lower the list prices of its drugs if the recent proposal by the Trump administration to change the current system of rebates was extended to the private market. If the policy was extended to the private market, how large would the list price reductions be relative to the size of the rebates your company is currently providing? Answer. Assuming the HHS rebate rule is finalized largely as proposed, AstraZeneca intends to comply with its requirements and use pointof-sale discounts. Our goal is to maintain net prices broadly in line with today, recognizing our ability to do so may be dependent on external factors and market response such as how plans evolve their benefit design and the total degree of transparency under the new model. AstraZeneca would plan to reduce list prices, pending reforms across all payers, including in the commercial sector in addition to Part D, as the current construct does not allow for two separate list prices (i.e., one list price for Part D and a different list price for the commercial sector). Therefore, we also support efforts to eliminate rebates in the commercial sector, and recommend that Congress explore such legislation. While eliminating rebates is an important step, benefit designs must also be evaluated. Question. How will this proposal affect how your company sets the list prices for new drug products? Answer. We believe that eliminating rebates across Medicare Part D and commercial will generally result in lower initial list prices than in the absence of reform, although the impact on specific medicines will vary based on the competitive dynamics for that medicine. Reform only in Part D and not commercial is unlikely to impact initial list price setting practices, as the current structure does not allow for two separate list prices (i.e., one list price for Part D and a different list price for the commercial sector). Question. If the proposal is finalized and not extended to the private market, will your company make any list price reductions? If so, how large would the reductions be relative to the size of the rebates your company is currently providing? Answer. AstraZeneca would plan to reduce list prices, pending reforms across all payers, including in the commercial sector in addition to Part D, as the current construct does not allow for two separate list prices (i.e., one list price for Part D and a different list price for the commercial sector). Therefore, we also support efforts to eliminate rebates in the commercial sector, and recommend that Congress explore such legislation. While eliminating rebates is an important step, benefit designs must also be evaluated. ______ Question Submitted by Hon. Maggie Hassan Question. In June of 2018, the Medicaid and CHIP Payment and Access Commission (MACPAC) unanimously recommended under Recommendation 1.1 in their annual report to Congress that Congress remove the statutory requirement that manufacturers blend the average manufacturer price (AMP) of a brand drug and its authorized generic.\3\ This requirement created an unintended loophole. Rather than use the price of the authorized generic, drug companies can sell its authorized generic to a corporate subsidiary at an artificially lower price, and use that lower price to bring down the AMP, which in turn lowers the rebate obligation. --------------------------------------------------------------------------- \3\ MACPAC, ``Improving Operations of the Medicaid Drug Rebate Program,'' https://www.macpac.gov/wp-content/uploads/2018/06/Improving- Operations-of-the-Medicaid-Drug-Rebate-Program.pdf. Does your company engage in this practice? Has your company ever --------------------------------------------------------------------------- engaged in this practice in the past? Answer. No. In limited circumstances, AstraZeneca has made authorized generics available, but does so through a third-party distributor, not an AstraZeneca subsidiary. ______ Questions Submitted by Hon. Catherine Cortez Masto Question. As a portion of your revenue, for what percentage of the drugs in your portfolio do you offer no rebates? Based on the drugs in your pipeline, do you foresee that portion growing? For those drugs, is your list price equal to your net price? Answer. All of our medicines are rebated under the statutory requirements of Medicaid, Federal Supply Schedule, 340B, and the Part D coverage gap discount program. For our highly innovative, targeted therapies, we do not typically provide additional rebates other than through our value-based agreements, where such discounts are based on patient outcomes. Therefore, due to statutory rebates and other fees and discounts, the net price is lower than list price for all medicines. Question. Do you invest more in R&D than you generate in U.S. sales revenue? Please include specific figures. Answer. In 2018, AstraZeneca's U.S. revenue was $6.88 billion. We invested $5.9 billion in R&D, globally. Question. Do you invest more in R&D than you spend on marketing and administration? What company functions do you consider to be included in administration? Please include specific figures. Answer. In 2018, we spent $5.9 billion on R&D and $10 billion on Selling, General and Administrative (SG&A) costs globally, which is inclusive of Sales and Marketing costs of $6.1 billion. Selling, General and Administrative expenses are defined as fixed costs of selling products and services and costs of central services and administration, which are not included in inventory values. General and administrative costs include costs of central services and administration, such as: Human Resources, Finance, Facilities, Purchasing, Strategy and Business Development, Legal, Corporate Affairs, and other corporate expenses. Our Sales and Marketing figures include all costs incurred in selling, marketing, promoting, and distributing our products. Question. Do you invest more in R&D than you spend on marketing and sales? What company functions do you consider to be included in sales? Please include specific figures. Answer. In 2018, we spent $5.9 billion on R&D and $6.1 billion on Sales and Marketing, globally. Our Sales and Marketing figures include all costs incurred in selling, marketing, promoting, and distributing our products. Question. Why do you advertise for the drugs you manufacture? What factors do you consider in choosing which drugs you advertise? Answer. We consider many factors when making decisions regarding the advertising of our medicines, including the opportunity to raise brand and disease awareness, patient education, and the enhancement of the patient/physician dialogue. We believe that health-care communications efforts can have a positive impact on patient health. AstraZeneca made a decision several years ago to use our direct-to-consumer (DTC) advertisements to share another important message with patients: We were the first company to include messages about our affordability programs in all of our DTC TV advertisements, making clear to patients that if they cannot afford their medicines, AstraZeneca may be able to help. We continue this practice today, which we believe is reflective of AstraZeneca's commitment to patient access and affordability. ______ Appendix A ------------------------------------------------------------------------ Organization Program Title Date Amount ------------------------------------------------------------------------ CARDIOVASCULAR RESEARCH Chronic Total 01/07/2014 $5,000.00 FOUNDATION Occlusion and Left Main Summit 2014: A Live Demonstration Course ------------------------------------------------------------------------ TORRANCE MEMORIAL Cardiology Update 01/08/2014 $2,500.00 MEDICAL CENTER 2014: Conventional Wisdom and Beyond ------------------------------------------------------------------------ SCRIPPS HEALTH Grand Rounds in 01/09/2014 $8,027.93 Cardiovascular Diseases ------------------------------------------------------------------------ UNIVERSITY OF CHICAGO Sixth Annual 01/12/2014 $3,000.00 Morton Arnsdorf Cardiovascular Research Day at the University of Chicago ------------------------------------------------------------------------ FLORIDA OSTEOPATHIC 15th Annual 01/15/2014 $5,000.00 MEDICAL ASSOCIATION Cardiovascular DISTRICT SOCIETY 2 and Medicine Symposium ------------------------------------------------------------------------ AMERICAN COLLEGE OF 25th Annual 01/16/2014 $5,000.00 CARDIOLOGY--PUERTO Meeting ACC RICO CHAPTER Puerto Rico Chapter ------------------------------------------------------------------------ NATIONAL ASSOCIATION OF Improving Patient 01/23/2014 $25,000.00 MANAGED CARE Outcomes: Updated PHYSICIANS Treatment Strategies in the Management of Acute Coronary Syndrome (ACS) ------------------------------------------------------------------------ UNIVERSITY MEDICAL 6th Annual 01/23/2014 $5,000.00 CENTER OF SOUTHERN Cardiovascular NEVADA and Stroke Symposium ------------------------------------------------------------------------ SAINT JOSEPH'S Antithrombotic 01/23/2014 $2,737.62 HOSPITAL--ATLANTA Protocol for Acute Coronary Sndrome ------------------------------------------------------------------------ GORDON RESERACH Gordon Research 01/26/2014 $1,700.00 CONFRENCE Seminar--``Lipopr otein Metabolism'' ------------------------------------------------------------------------ CLEVELAND CLINIC Rheumatology Best 01/26/2014 $9,795.58 EDUCATIONAL FOUNDATION Practices 6th Annual Rheumatology Highlights Report--``Transla ting an International Meeting into Clinical Practice'' ------------------------------------------------------------------------ KERN ASPEN LIPID Evolving Concepts 01/26/2014 $7,000.00 CONFERENCE of HDL Function in Cardiometabolic Diseases and Beyond ------------------------------------------------------------------------ ST. JOSEPH'S REGIONAL Acute Coronary 01/27/2014 $2,225.00 MEDICAL CENTER Syndrome: Evidence-Based Management in the Present Era ------------------------------------------------------------------------ NATIONAL LIPID Lipid Academy 01/28/2014 $20,000.00 ASSOCIATION Series of 2 ------------------------------------------------------------------------ NATIONAL LIPID Masters in 01/28/2014 $20,000.00 ASSOCIATION Lipidology Series of 2 ------------------------------------------------------------------------ REGENTS OF THE Rheumatology Grand 01/29/2014 $5,000.00 UNIVERSITY OF Rounds CALIFORNIA ------------------------------------------------------------------------ DUKE UNIVERSITY Overview of the 01/29/2014 $5,439.84 Duke Health Systems Acute Coronary Syndromes suggested algorithm of care ------------------------------------------------------------------------ PENNSYLVANIA ACADEMY OF PAFP/F Smoking 01/29/2014 $13,666.00 FAMILY PHYSICIANS Cessation and FOUNDATION Asthma Outcomes CME ------------------------------------------------------------------------ JOHNS HOPKINS Advances in the 01/30/2014 $30,000.00 UNIVERSITY Diagnosis and Treatment of the Rheumatic Diseases ------------------------------------------------------------------------ EMORY UNIVERSITY Emory Symposium on 01/30/2014 $5,000.00 Coronary Atherosclerosis Prevention and Education (ESCAPE) ------------------------------------------------------------------------ NURSE PRACTITIONER Clinical Pearls 01/30/2014 $5,000.00 ASSOCIATES FOR for COPD CONTINUING EDUCATION ------------------------------------------------------------------------ NATIONAL ASSOCIATION OF Practical 01/30/2014 $25,000.00 MANAGED CARE Strategies to PHYSICIANS Improve Patient Outcomes in the Prevention and Treatment of COPD ------------------------------------------------------------------------ ST. JOSEPH'S REGIONAL COPD 02/04/2014 $2,200.00 MEDICAL CENTER ------------------------------------------------------------------------ AMERICAN ASSOCIATION OF AACE 23rd Annual 02/04/2014 $16,130.00 CLINICAL Scientific and ENDOCRINOLOGISTS Clinical Congress ------------------------------------------------------------------------ NURSE PRACTITIONER Cardiovascular 02/04/2014 $5,000.00 ASSOCIATES FOR Pharmacology: CONTINUING EDUCATION Latest Updates in Caring for the Cardiac Patient ------------------------------------------------------------------------ MIDWEST CARDIOVASCULAR Cardiology at the 02/04/2014 $5,000.00 RESEARCH FOUNDATION Bix ------------------------------------------------------------------------ AMERICAN COLLEGE OF ACCs 63rd Annual 02/05/2014 $100,000.00 CARDIOLOGY FOUNDATION Scientific Session (ACC.14) Prevention Learning Pathway and Prevention Pilot Program ------------------------------------------------------------------------ LA BIOMED Cardiology Grand 02/05/2014 $5,000.00 Rounds: Updates in ACS ------------------------------------------------------------------------ NEBRASKA ACADEMY OF Ten Things You 02/05/2014 $5,500.00 PHYSICIAN ASSISTANTS Didn't Learn About COPD in Class (Even If You Were Paying Attention ------------------------------------------------------------------------ MINNESOTA SOCIETY OF MSHP Annual 02/05/2014 $2,533.00 HEALTH-SYSTEM Meeting 2014: PHARMACISTS Evidenced-based Updates in the Management of Dyslipidemia ------------------------------------------------------------------------ CARDIOVASCULAR RESEARCH 20th Annual 02/05/2014 $15,000.00 FOUNDATION Interventional Cardiology Fellows Course ------------------------------------------------------------------------ AMERICAN COLLEGE OF Best of ACC.14: 02/05/2014 $50,000.00 CARDIOLOGY FOUNDATION Take Home Messages for the Clinicians ------------------------------------------------------------------------ ENDOCRINE SOCIETY ENDO 2014 02/06/2014 $40,000.00 Educational Sessions ------------------------------------------------------------------------ ALL NYC EMERGENCY All NYC Emergency 02/06/2014 $5,000.00 MEDICINE CONFERENCE, Medicine INC. Conference; In the Footsteps of Giants ------------------------------------------------------------------------ AMERICAN COLLEGE OF Annual Scientific 02/09/2014 $10,000.00 PHYSICIANS; PUERTO Meeting RICO CHAPTER ------------------------------------------------------------------------ CARDIOVASCULAR RESEARCH Optimizing PCI 02/09/2014 $5,000.00 FOUNDATION Outcomes: A Vision for 2014 ------------------------------------------------------------------------ INTERNATIONAL 14th Annual 02/10/2014 $12,500.00 ASSOCIATION FOR THE Targeted STUDY OF LUNG CANCER Threapies of Lung Cancer Meeting ------------------------------------------------------------------------ TENNESSEE ACADEMY OF Breast and Ovarian 02/10/2014 $6,000.00 PHYSICIAN ASSISTANTS Cancer ------------------------------------------------------------------------ PURDUE UNIVERSITY A 2014 National 02/12/2014 $30,000.00 Educational Initiative on Therapeutics and Rheumatology for Rheumatology State Societies ------------------------------------------------------------------------ WEST PENN ALLEGHENY Cardiovascular 02/17/2014 $10,000.00 HEALTH SYSTEM, INC. Medicine Update ------------------------------------------------------------------------ MEDSTAR WASHINGTON 12th International 02/18/2014 $25,000.00 HOSPITAL CENTER Congress on Targeted Anticancer Therapies (TAT) ------------------------------------------------------------------------ THE BIBIKHAN FOUNDATION 7th Annual 02/18/2014 $5,000.00 Cardiovascular Update--``A Practical Tutortial'' ------------------------------------------------------------------------ SOCIETY OF GYNECOLOGIC SGO 45th Annual 02/19/2014 $25,000.00 ONCOLOGY Meeting on Women's Cancer ------------------------------------------------------------------------ GORDON RESEARCH Gordon Research 02/19/2014 $5,000.00 CONFERENCES Conferences on Cardiac Regulatory Mechanisms ------------------------------------------------------------------------ BAYLOR UNIVERSITY Emerging 02/20/2014 $17,460.00 MEDICAL CENTER DBA A. Therapeutic WEBB ROBERTS CENTER Options for Medullary Thyroid Cancer and Differentiated Thyroid Cancer ------------------------------------------------------------------------ ACADEMIA MEDICA DEL SUR- Cardiometabolic 02/20/2014 $20,000.00 FONDO EDUCACION MEDICA Health Congress CONTINUADA 2014 ------------------------------------------------------------------------ DUKE UNIVERSITY MEDICAL 13th Annual 02/25/2014 $5,498.41 CENTER Southeastern Fellows Research Skills Retreat ------------------------------------------------------------------------ THE UNIVERSITY OF 19th Annual 02/25/2014 $5,000.00 CHICAGO University of Chicago Phase II Consortium (UC P2C) Symposium ------------------------------------------------------------------------ INTERNATIONAL SOCIETY 60th Annual 02/25/2014 $25,000.00 ON THROMBOSIS AND Meeting of the HAEMOSTASIS Scientific and Standardization Committee (SSC) of the International Society on Thrombosis and Haemostasis (ISTH) ------------------------------------------------------------------------ THE UNIVERSITY OF Making Sense of 02/25/2014 $5,000.00 CHICAGO the Sequence: Genomics Primer for Clinical Cancer Genetic Practitioners ------------------------------------------------------------------------ WEST VIRGINIA ACADEMY Dyslipidemia and 02/25/2014 $2,500.00 OF FAMILY PHYSICIANS Atherosclerosis-- Reducing the Risk ------------------------------------------------------------------------ AMERICAN ACADEMY OF PediaLink 02/26/2014 $37,800.00 PEDIATRICS Influenza Course Series ------------------------------------------------------------------------ PREVENTIVE 20th Annual 02/26/2014 $15,000.00 CARDIOVASCULAR NURSES Symposium ASSOCIATION ------------------------------------------------------------------------ NATIONAL ASSOCIATION OF 2014 NAFC Annual 02/27/2014 $30,000.00 FREE and CHARITABLE Summit CLINICS ------------------------------------------------------------------------ VANDERBILT UNIVERSITY Cardiology 2014: 02/27/2014 $5,000.00 Advances in Science and Practice ------------------------------------------------------------------------ THE BOARD OF REGENTS OF Cardiovascular 02/27/2014 $5,000.00 THE UNIVERSITY OF Medicine and WISCONSIN SYSTEM Prevention Update for Primary Care ------------------------------------------------------------------------ SOCIETY FOR VASCULAR Society for 03/02/2014 $5,000.00 MEDICINE Vascular Medicine 25th Anniversary and Scientific Sessions ------------------------------------------------------------------------ AMERICAN ASSOCIATION 94th Annual 03/04/2014 $10,000.00 FOR THORACIC SURGERY Meeting American Association for Thoracic Surgery ------------------------------------------------------------------------ CHI ST. LUKE'S HEALTH Cardiology Grand 03/05/2014 $3,857.58 Rounds ------------------------------------------------------------------------ MIDWEST CARDIOVASCULAR Cardiovascular 03/05/2014 $5,000.00 RESEARCH FOUNDATION Interventions and Practice Guidelines ------------------------------------------------------------------------ UNIVERSITY OF ROCHESTER 27th Cardiology 03/05/2014 $4,805.00 Spring Update 2014 ------------------------------------------------------------------------ UNIVERSITY OF Clinical 03/05/2014 $4,000.00 WASHINGTON Cardiology Pearls for Primary Care Providers ------------------------------------------------------------------------ AMERICAN ACADEMY OF Faces and Cases: 03/06/2014 $50,000.00 PAIN MANAGEMENT Assessing and Managing People With Complex Chronic Pain ------------------------------------------------------------------------ PRESIDENT AND FELLOWS Pediatric Asthma 03/06/2014 $5,000.00 OF HARVARD COLLEGE and Allergy Updates for Primary Care Providers ------------------------------------------------------------------------ PRESIDENT AND FELLOWS Boston Bacterial 03/06/2014 $2,500.00 OF HARVARD COLLEGE Meeting 2014 ------------------------------------------------------------------------ CARDIOVASCULAR RESEARCH TCTMD 2014 Post 03/09/2014 $100,000.00 FOUNDATION Conference Web Cast Series ------------------------------------------------------------------------ CARDIOVASCULAR RESEARCH DAPT Dilemmas: A 03/09/2014 $66,913.46 FOUNDATION Case-based Roundtable Tutorial ------------------------------------------------------------------------ ASSOCIATION OF BLACK 40th Anniversary 03/11/2014 $20,000.00 CARDIOLOGISTS Annual Scientific Sessions The Ecology of Cardiovascular Disease in 2014: Trends, Challenges and Targets for 2025 ------------------------------------------------------------------------ THE HOPE FOUNDATION Spring 2014 SWOG 03/18/2014 $10,000.00 Group Meeting ------------------------------------------------------------------------ AMERICAN LUNG ALASD Asthma 03/18/2014 $2,500.00 ASSOCIATION OF THE Educator UPPER MIDWEST Institute ------------------------------------------------------------------------ AMERICAN SOCIETY OF Getting to Goal: 03/19/2014 $5,950.00 CONSULTANT PHARMACISTS The Pharmacist's FL CHAPTER Role in Managing Dyslipidemia and Atherosclerosis ------------------------------------------------------------------------ THE RESEARCH FOUNDATION Cal For Grants CGA 03/19/2014 $2,000.00 CV 1404--Time Critical Diagnosis (TCD) Symposium ------------------------------------------------------------------------ EMORY UNIVERSITY Emory Practical 03/19/2014 $3,000.00 Intervention Course (EPIC 2014) ------------------------------------------------------------------------ GORDON RESEARCH Gordon Research 03/20/2014 $5,000.00 CONFERENCES Conference and Seminar on Hemostasis ------------------------------------------------------------------------ PENNSYLVANIA ALLERGY 2014 Annual 03/20/2014 $5,000.00 AND ASTHMA ASSOCIATION Meeting of the Pennsylvania Allergy and Asthma Association ------------------------------------------------------------------------ ONCOLOGY NURSING Oncology Nursing 03/20/2014 $25,000.00 SOCIETY Society 39th Annual Congress ------------------------------------------------------------------------ RICHMOND UNIVERSITY Lipid Management 03/20/2014 $1,400.00 MEDICAL CENTER 2014 Guidelines and Beyond ------------------------------------------------------------------------ JOHNS HOPKINS 5th Annual Johns 03/23/2014 $2,500.00 UNIVERSITY Hopkins Cardiovascular Research Retreat ------------------------------------------------------------------------ AMERICAN ACADEMY OF Fall 2014 03/23/2014 $5,000.00 ALLERGY ASTHMA AND Symposium of the IMMUNOLOGY Los Angeles Society of Allergy, Asthma and Clinical Immunology ------------------------------------------------------------------------ UNIVERSITY OF FLORIDA Vascular Biology 03/23/2014 $15,000.00 Working Group US Chapter Meeting ------------------------------------------------------------------------ THE SOCIETY FOR 2014 SCAI 03/23/2014 $15,000.00 CARDIOVASCULAR Transradial ANGIOGRAPHY AND Interventional INTERVENTIONS Program (TRIP) Series ------------------------------------------------------------------------ ASPEN LUNG CONFERENCE Thomas L. Petty 03/24/2014 $5,000.00 Aspen Lung Conference: Rebuilding the Injured Lung ------------------------------------------------------------------------ INTERNATIONAL SOCIETY ISHIB 2014 Annual 03/24/2014 $10,000.00 ON HYPERTENSION IN Conference- BLACKS INC. Medical and Social Determinants of Cardiometabolic Health ------------------------------------------------------------------------ ARKANSAS ACADEMY OF 67th Annual 03/24/2014 $3,000.00 FAMILY PHYSICIANS Scientific Assembly of the Arkansas Academy of Family Physicians ------------------------------------------------------------------------ TRUSTEES OF THE Current Advances 03/24/2014 $5,000.00 UNIVERSITY OF in Cardiovascular PENNSYLVANIA Care 2014 ------------------------------------------------------------------------ ST. PETER'S HOSPITAL Cardiology 03/25/2014 $3,000.00 Teaching Day ------------------------------------------------------------------------ CHARLES R. DREW 18th Annual 03/26/2014 $25,000.00 UNIVERSITY OF MEDICINE Conference and SCIENCE ------------------------------------------------------------------------ GORDON RESEARCH 2014 GRC on 03/27/2014 $2,500.00 CONFERENCES Heterocyclic Compounds ------------------------------------------------------------------------ THE ROCKEFELLER Leptin and 03/30/2014 $25,000.00 UNIVERSITY Metabolic Disease: A Special Symposium on the 20th Anniversary of the Discovery of Leptin ------------------------------------------------------------------------ AMERICAN COLLEGE OF CSAAI's A 03/30/2014 $5,000.00 ALLERGY, ASTHMA AND Midsummer Night's IMMUNOLOGY Wheeze 2014 ------------------------------------------------------------------------ UNIVERSITY OF NEW PeerView Live, 04/01/2014 $353,000.00 MEXICO Using Evidence- Based Treatment to Optimize Control of Elevated Serum Triglycerides (150202699) ------------------------------------------------------------------------ THOMAS JEFFERSON Jefferson Critical 04/01/2014 $5,000.00 UNIVERSITY Care Symposium: A Multidisciplinary Review of Current Evidence and Controversies ------------------------------------------------------------------------ AMERICAN ASSOCIATION OF 35th Annual 04/01/2014 $3,000.00 ENDOCRINE SURGEONS Meeting of the American Association of Endocrine Surgeons ------------------------------------------------------------------------ GORDON RESEARCH 2014 Bioorganic 04/02/2014 $1,000.00 CONFERENCES Chemistry Gordon Research Conference ------------------------------------------------------------------------ THE NEW YORK Seventh Annual 04/03/2014 $3,050.00 CARDIOLOGICAL SOCIETY, Cardiac Care INC. Associate Symposium 2014 ------------------------------------------------------------------------ CLEVELAND CLINIC 15th Annual 04/03/2014 $4,706.02 EDUCATIONAL FOUNDATION Intensive Review of Cardiology ------------------------------------------------------------------------ WASHINGTON UNIVERSITY Cardiology Update 04/06/2014 $4,000.00 ------------------------------------------------------------------------ DIGNITY HEALTH ST. 16th Annual 04/06/2014 $6,000.00 BERNARDINE MEDICAL Cardiac Symposium CENTER ------------------------------------------------------------------------ CONQUER CANCER 2014 Conquer 04/09/2014 $24,000.00 FOUNDATION OF THE Cancer Foundation AMERICAN SOCIETY OF of ASCO Merit CLINICAL ONCOLOGY Awards ------------------------------------------------------------------------ MUNSTER MEDICAL New Frontiers in 04/09/2014 $4,200.00 RESEARCH FOUNDATION Cardiovascular DBA COMMUNITY HOSPITAL Disease 2014 ------------------------------------------------------------------------ GORDON RESEARCH 2014 Gordon 04/09/2014 $2,000.00 CONFERENCES Research Conference: Enzymes CoEnzymes and Metabolic Pathways ------------------------------------------------------------------------ AMERICAN COLLEGE 2014 Mississippi/ 04/09/2014 $5,000.00 PHYSICIANS--MISSISSIPP Louisiana ACP I CHAPTER Educational and Scientific Meeting ------------------------------------------------------------------------ ICHAN SCHOOL OF Live Symposium of 04/10/2014 $10,000.00 MEDICINE AT MOUNT Complex Coronary, SINAI Valvular and Vascular Cases ------------------------------------------------------------------------ NATIONAL FOUNDATION FOR Clinical 04/13/2014 $25,000.00 INFECTIOUS DISEASES Vaccinology Course ------------------------------------------------------------------------ AMERICAN ACADEMY OF The AAPA 2014 04/13/2014 $7,500.00 PHYSICIAN ASSISTANTS Annual Conference--Cardi ology Track ------------------------------------------------------------------------ NEW JERSEY ACADEMY OF Cardiovascular 04/13/2014 $5,000.00 FAMILY PHYSICIANS Controversies JNC8 and Cholesterol Treatment Guidelines (2014 Scientific Assembly) ------------------------------------------------------------------------ HUMBOLDT-DEL NORTE Asthma Update 04/14/2014 $4,000.00 COUNTY MEDICAL SOCIETY ------------------------------------------------------------------------ DANNEMILLER, INC. Contemporary 04/16/2014 $50,000.00 Perspectives in COPD: A Pulmonologist's Guide to Individualized Patient Care ------------------------------------------------------------------------ OKLAHOMA UNIVERSITY 17th Annual 04/16/2014 $3,000.00 HEALTH SCIENCE CENTER-- Primary Care OUHSC Update ------------------------------------------------------------------------ CONQUER CANCER 2014 Conquer 04/17/2014 $60,000.00 FOUNDATION OF THE Cancer Foundation AMERICAN SOCIETY OF of ASCO Young CLINICAL ONCOLOGY Investigator Award (YIA) ------------------------------------------------------------------------ CLEVELAND CLINIC 6th Annual E- 04/17/2014 $9,352.86 EDUCATIONAL FOUNDATION Journal Club: The Insights on Biologics and New Agents for Rheumatic Diseases ------------------------------------------------------------------------ NATIONAL FOUNDATION FOR 17th Annual 04/21/2014 $15,000.00 INFECTIOUS DISEASES Conference on Vaccine Research ------------------------------------------------------------------------ ECOG RESEARCH AND 2014 ECOG-ACRIN 04/21/2014 $5,000.00 EDUCATION FOUNDATION Spring Group Meeting ------------------------------------------------------------------------ METABOLIC ENDOCRINE Contemporary T2DM 04/21/2014 $229,200.00 EDUCATION FOUNDATION Management: Focus on Safety and Efficacy ------------------------------------------------------------------------ THE CHEST FOUNDATION The CHEST 04/21/2014 $35,000.00 Foundation Diversity Research/Women's Respiratory Health Awards Program ------------------------------------------------------------------------ MISSOURI ACADEMY OF Hyperlipidemia 04/21/2014 $5,000.00 PHYSICIAN ASSISTANTS ------------------------------------------------------------------------ REGENTS OF THE Lipidomics Impact 04/22/2014 $2,500.00 UNIVERSITY OF on Cell Biology, CALIFORNIA, SAN DIEGO Inflammation and Metabolic Disease ------------------------------------------------------------------------ NATIONAL MINORITY 11th Annual 04/23/2014 $30,000.00 QUALITY FORUM National Summit on Health Disparities ------------------------------------------------------------------------ DUKE UNIVERSITY 2014 Carolinas 04/24/2014 $20,000.00 COPD Symposium ------------------------------------------------------------------------ MICHIGAN STATE MEDICAL Rheumatology 04/24/2014 $3,000.00 SOCIETY FOUNDATION Update ------------------------------------------------------------------------ MAIN LINE HEALTH Atherosclerosis: 04/24/2014 $5,000.00 Prevention of Progression ------------------------------------------------------------------------ CASE MANAGEMENT SOCIETY CMSA 2014 Annual 04/27/2014 $15,000.00 OF AMERICA Conference and Expo ------------------------------------------------------------------------ NATIONAL COMPREHENSIVE NCCN 2014 Monthly 04/27/2014 $25,000.00 CANCER NETWORK, INC. Oncology Tumor Boards: A Multidisciplinary Approach to Individualized Patient Care ------------------------------------------------------------------------ AMERICAN HEART Arteriosclerosis, 04/27/2014 $20,000.00 ASSOCIATION, INC. Thrombosis, and Vascular Biology Scientific Sessions 2014 ------------------------------------------------------------------------ SCRIPPS HEALTH 25th Annual 04/27/2014 $5,000.00 Cardiovascular Interventions ------------------------------------------------------------------------ AMERICAN COLLEGE OF Interventional 04/27/2014 $5,000.00 CARDIOLOGY FOUNDATION Cardiology Board Preparatory Educational Package ------------------------------------------------------------------------ TEXAS ONE VOICE: A Designing 04/28/2014 $1,000.00 COLLABORATIVE FOR Healthcare in HEALTH AND HUMAN Texas How the SERVICES Past and Present will Guide the Future ------------------------------------------------------------------------ TRUSTEES OF THE Cardiology Update 04/28/2014 $10,000.00 UNIVERSITY OF 2014: A Patient PENNSYLVANIA Management Approach ------------------------------------------------------------------------ CONQUER CANCER 2014 ASCO Annual 05/04/2014 $56,000.00 FOUNDATION OF THE Meeting Lung AMERICAN SOCIETY OF Cancer Track CLINICAL ONCOLOGY ------------------------------------------------------------------------ FOUNDATION FOR CARE Dyslipidemia and 05/06/2014 $25,000.00 MANAGEMENT New Cholesterol Guidelines: What the Primary Care Provider Needs to Know ------------------------------------------------------------------------ AMERICAN COLLEGE OF Update in Allergy, 05/06/2014 $10,000.00 ALLERGY, ASTHMA AND Asthma and IMMUNOLOGY Immunology ------------------------------------------------------------------------ FLORIDA ACADEMY OF Update in the 05/06/2014 $5,000.00 PHYSICIAN ASSISTANTS Management of Dyslipidemia ------------------------------------------------------------------------ VASSAR BROTHERS MEDICAL 44th Annual 05/06/2014 $5,000.00 CENTER Cardiology Education Day ------------------------------------------------------------------------ ZOE ROSE MEMORIAL 2014 Preemie 05/06/2014 $10,000.00 FOUNDATION DBA PREEMIE Parent Summit PARENT ALLIANCE ------------------------------------------------------------------------ AMERICAN ASSOCIATION OF AACE 23rd Annual 05/07/2014 $25,000.00 CLINICAL Scientific and ENDOCRINOLOGISTS Clinical Congress ------------------------------------------------------------------------ LOUISIANA SOCIETY OF LSAAI 41st Annual 05/07/2014 $5,000.00 ALLERGY, ASTHMA AND Meeting IMMUNOLOGY ------------------------------------------------------------------------ AMERICAN ACADEMY OF AAFP Assembly 60 05/07/2014 $13,000.00 FAMILY PHYSICIANS Minute Lecture titled Chronic Obstructive Pulmonary Disorder (COPD) and Pulmonary Function Testing ------------------------------------------------------------------------ COLUMBUS COMMUNITY 2014 ASCO REVIEW 05/08/2014 $5,000.00 CLINICAL ONCOLOGY PROGRAM ------------------------------------------------------------------------ AMERICAN COLLEGE OF Aspen Allergy 05/08/2014 $10,000.00 ALLERGY, ASTHMA AND Conference IMMUNOLOGY ------------------------------------------------------------------------ AMERICAN DIABETES 29th Annual 05/11/2014 $20,000.00 ASSOCIATION Clinical Conference on Diabetes--Reducin g Risks: Primary and Secondary ------------------------------------------------------------------------ REGENTS OF THE 20th Annual UCLA 05/11/2014 $5,000.00 UNIVERSITY OF Symposium CALIFORNIA Pulmonary Function and Exercise Testing: Practical Approaches for the Healthcare Practitioner ------------------------------------------------------------------------ AMERICAN COLLEGE OF The Changing 05/11/2014 $5,000.00 ALLERGY, ASTHMA AND Allergy Practice IMMUNOLOGY ------------------------------------------------------------------------ AMERICAN COLLEGE OF Caribbean Congress 05/12/2014 $5,000.00 EMERGENCY PHYSICIANS, on Emergency PUERTO RICO CHAPTER Medicine ------------------------------------------------------------------------ CLEVELAND CLINIC 19th Annual 05/13/2014 $6,613.34 EDUCATIONAL FOUNDATION Diabetes Day: Diabetes Therapy ------------------------------------------------------------------------ THE REGENTS UNIVERSITY UCLA Family 05/13/2014 $7,500.00 OF CALIFORNIA Medicine Refresher Course ------------------------------------------------------------------------ CLEVELAND CLINIC ASCO Review 05/13/2014 $4,000.00 EDUCATIONAL FOUNDATION ------------------------------------------------------------------------ SOCIEDAD PUERTORRIQUENA Puerto Rican 05/14/2014 $10,000.00 DE ENDOCRINOLOGIA Y Endocrinology and DIABETOLOGIA Diabetes Society Scientific Meeting ------------------------------------------------------------------------ NATIONAL MEDICAL Asthma as a Model 05/14/2014 $25,000.00 ASSOCIATION Chronic Illness ------------------------------------------------------------------------ GORDON RESEARCH 2014 Lipoprotein 05/14/2014 $2,500.00 CONFERENCES Metabolism Gordon Research Conference ------------------------------------------------------------------------ ONCOLOGY NURSING Pharmacology 05/14/2014 $5,000.00 SOCIETY Update:Integratin g Advances into Practice ------------------------------------------------------------------------ AMERICAN ASSOCIATION OF 2014 National 05/14/2014 $5,000.00 SERVICE COORDINATORS Service Coordinator Conference ------------------------------------------------------------------------ MAYO CLINIC ARIZONA Cardiology Update 05/15/2014 $10,000.00 2014: The Heart of the Matter ------------------------------------------------------------------------ AMERICAN CHEMICAL 2014 ACS National 05/18/2014 $1,000.00 SOCIETY--DIVISION OF Medicinal MEDICINAL CHEMISTRY Chemistry Symposium ------------------------------------------------------------------------ CHICAGO ASTHMA Emergency 05/18/2014 $2,000.00 CONSORTIUM Management of Asthma ------------------------------------------------------------------------ SUFFOLK ACADEMY OF 31st Update in 05/19/2014 $3,000.00 MEDICINE Allergy and Immunology Symposium ------------------------------------------------------------------------ EMORY UNIVERSITY Discussing Cases 05/19/2014 $20,000.00 with Diabetes Experts ------------------------------------------------------------------------ NATIONAL MEDICAL Evidence-Based 05/19/2014 $23,405.00 ASSOCIATION Diagnosis and Management of Asthma and COPD: Practical Tools to Improve Patient Care ------------------------------------------------------------------------ NORTH SHORE LONG ISLAND Post American 05/19/2014 $3,000.00 JEWISH HEALTH SYSTEM Society of Clinical Oncology Update 2014 ------------------------------------------------------------------------ LAHEY CLINIC HOSPITAL, Cardiovascular 05/19/2014 $6,000.00 INC. Disease: State of the Art 2014 ------------------------------------------------------------------------ AMERICAN COLLEGE OF 2014 05/19/2014 $5,000.00 CARDIOLOGY FOUNDATION Cardiovascular Board Review for Certification and Recertification Educational Package ------------------------------------------------------------------------ NEW JERSEY ACADEMY OF The Current 05/21/2014 $2,500.00 FAMILY PHYSICIANS Standards Of Care and Treatment of Diabetes (2014 Scientific Assembly) ------------------------------------------------------------------------ CONQUER CANCER 2014 Conquer 05/21/2014 $250,000.00 FOUNDATION OF THE Cancer Foundation AMERICAN SOCIETY OF of ASCO Career CLINICAL ONCOLOGY Development Award (CDA) ------------------------------------------------------------------------ NORTHWESTERN UNIVERSITY 16th Annual Lynn 05/21/2014 $10,000.00 Sage Breast Cancer Symposium ------------------------------------------------------------------------ PENNSYLVANIA SOCIETY OF Lipid Management 05/21/2014 $5,000.00 PHYSICIAN ASSISTANTS The Skinny on the Fat ------------------------------------------------------------------------ DUKE UNIVERSITY 1st Annual Duke 05/29/2014 $10,000.00 Preventive Cardiology Symposium ------------------------------------------------------------------------ ALZHEIMER'S ASSOCIATION 2014 Alzheimer's 05/29/2014 $95,000.00 Association International Conference ------------------------------------------------------------------------ TRUSTEES OF THE 2014 Updates in 05/29/2014 $5,000.00 UNIVERSITY OF Oncology: With PENNSYLVANIA Proceedings from International Medical Meetings ------------------------------------------------------------------------ SOCIETY FOR Young Investigator 06/01/2014 $25,000.00 NEUROSCIENCE Award ------------------------------------------------------------------------ METABOLIC ENDOCRINE The Role of the 06/03/2014 $149,025.00 EDUCATION FOUNDATION Kidney in Glucose Homeostasis and Diabetes ------------------------------------------------------------------------ VIVA PHYSICIANS VIVA 14: Vascular 06/03/2014 $20,000.00 InterVentional Advances ------------------------------------------------------------------------ SOCIETY OF TOXICOLOGIC Translational 06/04/2014 $3,000.00 PATHOLOGY Pathology: Relevance of Toxicologic Pathology to Human Health ------------------------------------------------------------------------ UHS PROFESSIONAL Gout and 06/04/2014 $100,825.00 EDUCATION PROGRAMS, Hyperuricemia--Cl INC. inical Spectrum and Management Update ------------------------------------------------------------------------ AMERICAN ACADEMY OF AAFP Assembly 60 06/04/2014 $10,000.00 FAMILY PHYSICIANS Minute Lecture titled Acute Coronary Syndrome and Angina (Fundamentals) ------------------------------------------------------------------------ AMERICAN ACADEMY OF AAFP Assembly 60 06/04/2014 $10,000.00 FAMILY PHYSICIANS Minute Lecture titled Acute Coronary Syndrome and Angina (Advanced) ------------------------------------------------------------------------ THE NEPHCURE FOUNDATION 10th International 06/04/2014 $5,000.00 Podocyte Conference ------------------------------------------------------------------------ ICAHN SCHOOL OF Mount Sinai 06/09/2014 $2,500.00 MEDICINE AT MOUNT Division of SINAI Occupational Medicine seminar series ------------------------------------------------------------------------ SWEDISH MEDICAL CENTER Cardiology Update 06/09/2014 $5,000.00 FOUNDATION for Primary Care ------------------------------------------------------------------------ JOSLIN DIABETES CENTER The Institute of 06/11/2014 $15,000.00 Lifestyle Medicine 2014 Educational Activities ------------------------------------------------------------------------ CARDIOVASCULAR RESEARCH ACS/STEMI: Focus 06/11/2014 $60,000.00 FOUNDATION on Acute Care ------------------------------------------------------------------------ PENN STATE COLLEGE OF 20th Annual 06/18/2014 $7,000.00 MEDICINE Pennsylvania Immunization ------------------------------------------------------------------------ AMERICAN SOCIETY FOR ASPMN 24th 06/18/2014 $10,000.00 PAIN MANAGEMENT National NURSING Conference ------------------------------------------------------------------------ AMERICAN PHARMACISTS APhA Pharmacy- 06/18/2014 $2,500.00 ASSOCIATION Based Immunization Delivery ------------------------------------------------------------------------ WASHINGTON UNIVERSITY Mentors in 06/22/2014 $50,000.00 Medicine ------------------------------------------------------------------------ PONCE MEDICAL SCHOOL Advances in 06/24/2014 $5,000.00 FOUNDATION INC. Dyslipidemia and Atherosclerosis Management ------------------------------------------------------------------------ AMERICAN COLLEGE OF Cardiovascular 06/25/2014 $15,000.00 EMERGENCY PHYSICIANS Disease Track at ACEP 2014 Scientific Assembly ------------------------------------------------------------------------ THE BRIGHAM AND WOMEN'S BWH Thyroid 06/26/2014 $3,000.00 HOSPITAL INC. Visiting Professor and Endocrine Grand Rounds Speaker ------------------------------------------------------------------------ WASHINGTON UNIVERSITY Clinical Allergy 06/26/2014 $5,000.00 for the Practicing Physician ------------------------------------------------------------------------ PREVENTIVE Fall Programs 06/26/2014 $5,000.00 CARDIOVASCULAR NURSES ASSOCIATION ------------------------------------------------------------------------ GORDON RESEARCH 2014 Gordon 06/26/2014 $500.00 CONFERENCES Research Seminar on Synaptic Transmission ------------------------------------------------------------------------ GREENWOOD LEFLORE Call for Grants: 06/29/2014 $2,500.00 HOSPITAL CGA Educating the Delta on Asthmatic Patients ------------------------------------------------------------------------ GORDON RESEARCH Gordon Research 06/29/2014 $2,000.00 CONFERENCE Conference on Multi-Drug Efflux Systems ------------------------------------------------------------------------ GORDON RESEARCH Gordon Research 06/29/2014 $2,000.00 CONFERENCES Conference: DNA Topoisomerases in Biology and Medicine ------------------------------------------------------------------------ ALBANY COLLEGE OF Heart to Heart: 06/30/2014 $14,000.00 PHARMACY AND HEALTH Updates on SCIENCES Cardiovascular Disease and the Management of Cholesterol and Hypertension ------------------------------------------------------------------------ CANCER MOLECULAR Molecular 06/30/2014 $5,000.00 THERAPEUTICS RESEARCH Therapeutics of ASSOCIATION Cancer Conference 2014 ------------------------------------------------------------------------ VANDERBILT UNIVERSITY Vanderbilt 07/08/2014 $3,000.00 University Hematology Oncology Educational Symposium ------------------------------------------------------------------------ CHILDREN'S HOSPITAL Translating Neural 07/08/2014 $3,000.00 CORPORATION Circuits and Pathways into Treatments ------------------------------------------------------------------------ PENNSYLVANIA SOCIETY OF Breast Cancer- 07/09/2014 $3,000.00 PHYSICIAN ASSISTANTS Fight Like a Girl ------------------------------------------------------------------------ PROMEDICA ACADEMIC After the 07/09/2014 $2,500.00 HEALTH CENTER Diagnosis: CORPORATION Helping Cardiopulmonary Patients Succeed-- Approaches to Stay Ahead of the Curve ------------------------------------------------------------------------ CONQUER CANCER 2014 Breast Cancer 07/09/2014 $10,000.00 FOUNDATION OF THE Symposium AMERICAN SOCIETY OF CLINICAL ONCOLOGY ------------------------------------------------------------------------ NURSE PRACTITIONER Hyperlipidemia and 07/09/2014 $5,000.00 ASSOC. FOR CONTINUING Hypertension in EDUCATION 2014: What's New in Treatment Guidelines ------------------------------------------------------------------------ DIABLO SOCIETY OF Cost-Effective 07/10/2014 $5,600.00 HEALTH SYSTEM Genotype-Guided PHARMACISTS Antiplatelet Therapy with Ticagrelor ------------------------------------------------------------------------ ALAMO CITY CANCER 12th Annual Breast 07/10/2014 $1,500.00 COUNCIL Cancer Conference Update ------------------------------------------------------------------------ UNIVERSITY OF TEXAS 37TH Annual San 07/10/2014 $10,000.00 HEALTH SCIENCE CENTER Antonio Breast SAN ANTONIO SCHOOL OF Cancer Symposium MEDICINE ------------------------------------------------------------------------ NATIONAL ASSOCIATION OF Best Practices in 07/15/2014 $25,000.00 MANAGED CARE the Prevention PHYSICIANS and Management of Chronic Obstructive Pulmonary Disease (COPD) ------------------------------------------------------------------------ CEDARS-SINAI MEDICAL Advances in Care 07/17/2014 $3,000.00 CENTER for the New Millennium: 20th Anniversary BRCA Gene Symposium ------------------------------------------------------------------------ NATIONAL ASSOCIATION OF Current Treatments 07/17/2014 $25,000.00 MANAGED CARE and Novel PHYSICIANS Strategies in the Management of Acute Coronary Syndrome (ACS) ------------------------------------------------------------------------ MARSHA RIVKIN CENTER 10th Biennial 07/22/2014 $5,000.00 FOR OVARIAN CANCER Ovarian Cancer RESEARCH Research Symposium ------------------------------------------------------------------------ FLORIDA ASSOCIATION OF Optimizing Oral 07/22/2014 $9,600.00 CONSULTANT PHARMACISTS Antiplatelet Therapy in Acute Coronary Syndrome ------------------------------------------------------------------------ AMERICAN COLLEGE OF Foundations for 07/22/2014 $10,000.00 CARDIOLOGY FOUNDATION Practice Excellence: Core Curriculum for the Cardiovascular Clinician 2014 ------------------------------------------------------------------------ METABOLIC ENDOCRINE 12th Annual World 07/23/2014 $100,000.00 EDUCATION FOUNDATION Congress on Insulin Resistance Diabetes and Cardiovascular Disease--WCIRDC ------------------------------------------------------------------------ AMERICAN ASSOCIATION OF Program Title 07/23/2014 $3,000.00 ENDOCRINE SURGEONS Masters Course in FOUNDATION Endocrine Surgery ------------------------------------------------------------------------ CARDIOVASCULAR RESEARCH Acute Coronary 07/24/2014 $20,000.00 FOUNDATION Syndromes, Pharmacotherapy and Shock/ Hemodynamic Support ------------------------------------------------------------------------ CARDIOVASCULAR RESEARCH Town Hall and 07/24/2014 $20,000.00 FOUNDATION FDA Clinical Trial Design and Interpretation ------------------------------------------------------------------------ MINNESOTA PHARMACISTS MPhA Annual 07/24/2014 $2,150.00 ASSOCIATION Meeting: MTM in Cardiology Clinic ------------------------------------------------------------------------ AMERICAN ACADEMY OF 6th Annual 07/29/2014 $5,000.00 PHYSICIAN ASSISTANTS Allergy, Asthma IN ALLERGY, ASTHMA AND and ENT CME IMMUNOLOGY Conference ------------------------------------------------------------------------ AMERICAN COLLEGE OF Severe Asthma 07/29/2014 $22,000.00 ALLERGY, ASTHMA AND Workshop at the IMMUNOLOGY 2014 ACAAI Annual Scientific Meeting ------------------------------------------------------------------------ INTERNATIONAL 16th World 07/29/2014 $30,000.00 ASSOCIATION FOR THE Conference on STUDY OF LUNG CANCER Lung Cancer ------------------------------------------------------------------------ AMERICAN COLLEGE OF The Affordable 07/29/2014 $22,000.00 ALLERGY, ASTHMA AND Care Act and IMMUNOLOGY Asthma Control ------------------------------------------------------------------------ DANA-FARBER CANCER Dana-Farber Cancer 07/31/2014 $2,400.00 INSTITUTE Institute's 10th Annual Postdoctoral and Graduate Student Retreat ------------------------------------------------------------------------ NATIONAL ASSOCIATION 2014 NAHQ 39th 07/31/2014 $15,000.00 FOR HEALTHCARE QUALITY Annual Educational Conference ------------------------------------------------------------------------ ICAHN SCHOOL OF 2014 Top Ten 07/31/2014 $10,000.00 MEDICINE AT MOUNT Advances in SINAI Clinical Cardiology ------------------------------------------------------------------------ AMERICAN COLLEGE OF COPD/Asthma Track 07/31/2014 $25,800.00 CHEST PHYSCIANS at CHEST 2014 ------------------------------------------------------------------------ DREXEL UNIVERSITY Hypertension 08/03/2014 $5,000.00 HighLights-ASH 2014 ------------------------------------------------------------------------ ASSOCIATION OF No Gout About It: 08/03/2014 $9,500.00 REPRODUCTIVE HEALTH Targeted Provider PROFESSIONALS Education and Training to Screen, Diagnosis, and Manage Gout among Female Patients ------------------------------------------------------------------------ AMERICAN ASSOCIATION AACR Tumor 08/03/2014 $10,000.00 FOR CANCER RESEARCH Immunology and Immunotherapy: A New Chapter ------------------------------------------------------------------------ THE OHIO STATE Sixth Annual 08/05/2014 $5,000.00 UNIVERSITY Contemporary Multidisciplinary Cardiovascular Conference ------------------------------------------------------------------------ WAYNE STATE UNIVERSITY Update in 08/05/2014 $5,000.00 Rheumatology ------------------------------------------------------------------------ AMERICAN COLLEGE OF COPD Interactive 08/06/2014 $20,000.00 CHEST PHYSICIANS Educational Game ------------------------------------------------------------------------ NATIONAL ASSOCIATION OF Updates in the 08/06/2014 $25,000.00 MANAGED CARE Treatment of PHYSICIANS, INC. Hypertriglyceride mia: A Closer Look at the Role of Omega-3 Fatty Acids ------------------------------------------------------------------------ NATIONAL JEWISH HEALTH 19th Annual Allied 08/07/2014 $2,500.00 Health Regional Conference ------------------------------------------------------------------------ WESTERN SOCIETY OF WSAAI 53rd Annual 08/07/2014 $15,000.00 ALLERGY, ASTHMA AND Scientific IMMUNOLOGY Session ------------------------------------------------------------------------ DELAWARE ACADEMY OF Acute Coronary 08/07/2014 $3,500.00 PHYSICIAN ASSISTANTS Syndromes: Acute Myocardial Infarction and Unstable Angina ------------------------------------------------------------------------ AMERICAN PHARMACISTS Addressing Racial 08/10/2014 $25,000.00 ASSOCIATION and Ethnic Healthcare Disparities in Diabetes ------------------------------------------------------------------------ THOMAS JEFFERSON Current Issues in 08/10/2014 $10,000.00 UNIVERSITY Coronary and Structural Heart Disease: A Multidisciplinary Approach ------------------------------------------------------------------------ UNIVERSITY OF University of 08/11/2014 $5,000.00 WASHINGTON CME OFFICE Washington Topics in Allergy and Immunology Teaching Series 2014-2015 ------------------------------------------------------------------------ FOUNDATION OF THE The Foundation of 08/11/2014 $50,000.00 NATIONAL LIPID the National ASSOCIATION Lipid Association Hunninghake FH Abstract Award ------------------------------------------------------------------------ NATIONAL ASSOCIATION OF NANN 30th Annual 08/13/2014 $10,000.00 NEONATAL NURSES Educational Conference ------------------------------------------------------------------------ AMERICAN SOCIETY FOR ASTRO 56th Annual 08/17/2014 $3,000.00 RADIATION ONCOLOGY Meeting (ASTRO) ------------------------------------------------------------------------ AMERICAN SOCIETY OF SGLT2 Inhibitor 08/17/2014 $170,000.00 NEPHROLOGY Therapy in Patients with Mild to Moderate Diabetic Kidney Disease ------------------------------------------------------------------------ PRESIDENT AND FELLOWS Multidisciplinary 08/17/2014 $4,500.00 OF HARVARD COLLEGE Breast Rounds ------------------------------------------------------------------------ METABOLIC ENDOCRINE Contemporary T2DM 08/17/2014 $376,125.00 EDUCATION FOUNDATION Management: Focus on Safety and Efficacy (Live Program) ------------------------------------------------------------------------ MISSISSIPPI HEALTHCARE STEMI Protocols 08/17/2014 $1,464.83 ALLIANCE ------------------------------------------------------------------------ AMERICAN ASSOCIATION OF Practical 08/19/2014 $144,399.00 DIABETES EDUCATORS Applications of Pramlintide in Type 1 Diabetes ------------------------------------------------------------------------ AMERICAN SOCIETY OF Novel Treatments 08/19/2014 $252,000.00 HEALTH-SYSTEM for the PHARMACISTS Management of Type 2 Diabetes: Focus on SGLT2 Inhibitors ------------------------------------------------------------------------ THE SOCIETY FOR SCAI 2014 08/19/2014 $50,000.00 CARDIOVASCULAR Interventional ANGIOGRAPHY AND Cardiology INTERVENTIONS Fellows Courses ------------------------------------------------------------------------ OLIGONUCLEOTIDE 10th Annual 08/19/2014 $10,000.00 THERAPEUTICS SOCIETY Meeting of the Oligonucleotide Therapeutics Society ------------------------------------------------------------------------ SOCIETY FOR THE Advances in Cancer 08/19/2014 $75,000.00 IMMUNOTHERAPY OF Immunotherapy--Se CANCER ries of 5 Regional Programs ------------------------------------------------------------------------ AMERICAN ACADEMY OF The Sixth Annual 08/19/2014 $7,500.00 PHYSICIAN ASSISTANTS Hospital Medicine Boot Camp ------------------------------------------------------------------------ UNIVERSITY OF CAll for Grants 08/21/2014 $25,800.00 CINCINNATI Application (CGA) CV14-1st Annual Cincinnati Collaborative Cardiovascular Consortium (C4): Practical and Contemporary Cardiology 2014 ------------------------------------------------------------------------ WAYNE STATE UNIVERSITY Pulmonary, 08/27/2014 $3,000.00 Critical Care and Sleep Medicine Update 2014 ------------------------------------------------------------------------ INTERNATIONAL SOCIETY ISAM Textbook of 08/27/2014 $10,000.00 FOR AEROSOLS IN Aerosol Medicine MEDICINE ------------------------------------------------------------------------ NURSE PRACTITIONER Asthma and COPD 08/27/2014 $5,000.00 ASSOCIATES FOR 2014 CONTINUING EDUCATION (NPACE) ------------------------------------------------------------------------ AMERICAN COLLEGE OF CHEST 2014 Lung 08/27/2014 $24,150.00 CHEST PHYSCIANS Cancer Track ------------------------------------------------------------------------ THE UNIVERSITY OF TEXAS Medical Oncology 08/28/2014 $3,000.00 MD ANDERSON CANCER and Hematology CENTER 2014: Multidisciplinary Approaches that Improve Coordination of Care ------------------------------------------------------------------------ NATIONAL JEWISH HEALTH 37th Annual 08/28/2014 $5,000.00 Pulmonary and Allergy Update ------------------------------------------------------------------------ NOT-FOR-PROFIT HOSPITAL Management and 08/28/2014 $2,400.00 CORPORATION Prevention of Acute Exacerbation of COPD (AECOPD) ------------------------------------------------------------------------ AMERICAN ASSOCIATION OF New Jersey--AACE 08/31/2014 $5,000.00 CLINICAL 7th Annual ENDOCRINOLOGISTS Meeting ------------------------------------------------------------------------ WILLIAM BEAUMONT Practical and 08/31/2014 $2,000.00 HOSPITAL Progressive Updates in Primary Care Medicine ------------------------------------------------------------------------ AMERICAN COLLEGE OF 47th Annual New 08/31/2014 $15,000.00 CARDIOLOGY FOUNDATION York Cardiovascular Symposium: Major Topics in Cardiology Today ------------------------------------------------------------------------ INTERNATIONAL IASLC Fellowships 09/02/2014 $43,000.00 ASSOCIATION FOR THE STUDY OF LUNG CANCER ------------------------------------------------------------------------ RUTGERS, THE STATE Update in 09/02/2014 $7,500.00 UNIVERSITY OF NEW Rheumatology 2014 JERSEY ------------------------------------------------------------------------ CHILDREN'S HEALTHCARE Respiratory Update 09/02/2014 $3,000.00 OF ATLANTA 2014 ------------------------------------------------------------------------ UNIVERSITY OF MARYLAND, Patient-Focused 09/02/2014 $10,000.00 BALTIMORE FOUNDATION Drug Development ------------------------------------------------------------------------ THE ANGIOGENESIS World Congress on 09/02/2014 $5,000.00 FOUNDATION Angiogenesis ------------------------------------------------------------------------ JOHNS HOPKINS New Therapeutic 09/02/2014 $20,000.00 UNIVERSITY Insights/Advances in Allergic Diseases ------------------------------------------------------------------------ GORDON RESEARCH Mammalian DNA 09/02/2014 $5,000.00 CONFERENCES Repair Gordon Research Conference and Seminar 2015 ------------------------------------------------------------------------ ILLINOIS ACADEMY OF Health Care Reform 09/04/2014 $2,000.00 FAMILY PHYSICIANS and Care Coordination ------------------------------------------------------------------------ EXCELLENCE IN Rheumatology 09/04/2014 $25,000.00 RHEUMATOLOGY EDUCATION Winter Clinical Symposium 2015 ------------------------------------------------------------------------ SOCIETY OF INFECTIOUS Society of 09/04/2014 $5,000.00 DISEASES PHARMACISTS Infectious Diseases Pharmacists Research Grant Program ------------------------------------------------------------------------ CARDIOVASCULAR CVIs 21st Annual 09/09/2014 $10,000.00 INSTITUTE OF Cardiology PHILADELPHIA Update: Clinical Management of Heart Disease 2014 ------------------------------------------------------------------------ PROVIDENCE HOLY CROSS Acute Coronary 09/09/2014 $1,900.00 MEDICAL CENTER Syndrome ------------------------------------------------------------------------ DUKE UNIVERSITY 14th Annual 09/14/2014 $10,000.00 Southeastern Fellows Research Skills and Training Workshop ------------------------------------------------------------------------ PHILLIPS GILMORE Atlanta Lung 09/14/2014 $3,000.00 ONCOLOGY Cancer Symposium COMMUNICATIONS, INC. 2014 ------------------------------------------------------------------------ ECOG RESEARCH AND 2014 ECOG-ACRIN 09/14/2014 $5,000.00 EDUCATION FOUNDATION Fall Group Meeting ------------------------------------------------------------------------ THE NEW YORK ACADEMY OF Pharmacologic 09/14/2014 $10,000.00 SCIENCES Resolution of Inflammation as a Novel Therapeutic Approach ------------------------------------------------------------------------ MEDICAL COLLEGE OF 8th Annual 09/15/2014 $3,000.00 WISCONSIN Translational Oncology Research Symposium ------------------------------------------------------------------------ FRIENDS OF CANCER Friends of Cancer 09/15/2014 $100,000.00 RESEARCH Research 2014 programs ------------------------------------------------------------------------ UNIVERSITY OF FLORIDA Vascular Biology 09/15/2014 $15,000.00 Working Group Global Chapter Meting ------------------------------------------------------------------------ ORLANDO HEALTH Advancements in 09/15/2014 $3,000.00 the Early Detection and Treatment of Breast and Gynecologic Malignancies ------------------------------------------------------------------------ YALE UNIVERSITY Severe Asthma 09/17/2014 $5,000.00 2014: A Personalized Approach To Treatment ------------------------------------------------------------------------ EAST TENNESSEE STATE Asthma and Allergy 09/17/2014 $3,000.00 UNIVERSITY RESEARCH 2014: What's New, FOUNDATION What's Hot ------------------------------------------------------------------------ AMERICAN COLLEGE OF 2014 ACG 09/17/2014 $25,000.00 GASTROENTEROLOGY Presidential Poster Award ------------------------------------------------------------------------ PARTNERS HEALTHCARE 2014 Personalized 09/17/2014 $15,000.00 SYSTEM INC. Medicine Conference ------------------------------------------------------------------------ PERSONALIZED MEDICINE Turning the Tide 09/17/2014 $5,000.00 COALITION Against Cancer 2014 National Conference ------------------------------------------------------------------------ CEDARS-SINAI MEDICAL Rheumatology Grand 09/21/2014 $5,000.00 CENTER Rounds 2014 ------------------------------------------------------------------------ AMERICAN THYROID Early Riser 09/21/2014 $125,900.00 ASSOCIATION Symposium: Medullary Thyroid Cancer ------------------------------------------------------------------------ SAFETY PHARMACOLOGY 14th Annual Safety 09/21/2014 $3,000.00 SOCIETY Pharmacology Society Annual Meeting ------------------------------------------------------------------------ AMERICAN SOCIETY OF 19th Annual ASHP 09/23/2014 $10,000.00 HEALTH-SYSTEM Conference for PHARMACISTS Leaders in Health- System Pharmacy ------------------------------------------------------------------------ AMERICAN ASSOCIATION OF Scenes and 09/23/2014 $35,000.00 CLINICAL Seminars on ENDOCRINOLOGISTS Hypoglycemia Management: Multidisciplinary Approaches to Improving Safety for Patients with Diabetes ------------------------------------------------------------------------ NATIONAL COMPREHENSIVE 2014 NCCN Congress 09/23/2014 $25,000.00 CANCER NETWORK, INC. Series: Utilizing Guidelines to Customize Patient Care in Non-Small Cell Lung Cancer ------------------------------------------------------------------------ CITY OF HOPE NATIONAL Multidisciplinary 09/25/2014 $3,000.00 MEDICAL CENTER Approaches to Cancer Symposium ------------------------------------------------------------------------ THE DEUEL CONFERENCE ON The 2015 Deuel 09/30/2014 $15,000.00 LIPIDS Conference on Lipids ------------------------------------------------------------------------ AMERICAN COLLEGE OF 2014 ACR/ARHP 09/30/2014 $50,000.00 RHEUMATOLOGY Annual Meeting Gout Educational Track ------------------------------------------------------------------------ NORTH AMERICAN SOCIETY NASPGHAN Research 09/30/2014 $4,000.00 FOR PEDIATRIC Skills Workshop GASTROENTEROLOGY, HEPATOLOGY AND NUTRITION ------------------------------------------------------------------------ SOCIETY FOR THE SITC Workshop on 10/03/2014 $100,000.00 IMMUNOTHERAPY OF Combination CANCER Immunotherapy: Where Do We Go From Here? ------------------------------------------------------------------------ LETTERS and SCIENCES PARP Inhibition 10/07/2014 $275,478.44 for BRCA 1/2 Mutation- Associated Cancers and Triple Negative BC Advances in Risk Reduction and Treatment ------------------------------------------------------------------------ CHILDREN'S HOSPITAL Taking on 10/07/2014 $5,000.00 CORPORATION Tomorrow: Global Pediatric Innovation Summit and Awards 2014 ------------------------------------------------------------------------ ENZYME MECHANISMS 24th Enzyme 10/07/2014 $3,000.00 CONFERENCE, INC. Mechanisms Conference ------------------------------------------------------------------------ NAMI MARYLAND 2014 NAMI Maryland 10/07/2014 $5,000.00 Annual Education Conference ------------------------------------------------------------------------ GORDON RESEARCH Inhibition in the 10/07/2014 $5,000.00 CONFERENCES CNS Gordon Research Conference and Seminar ------------------------------------------------------------------------ AMERICAN COLLEGE OF Cardiometabolic 10/08/2014 $150,000.00 CARDIOLOGY FOUNDATION Clinical Community on CardioSource/ ACC.org ------------------------------------------------------------------------ NATIONAL ASSOCIATION Managing Pain in 10/09/2014 $25,000.00 DIRECTORS OF NURSING LTC Residents: ADMINISTRATION/LTC, Addressing INC. Opioiod-Induced Constipation ------------------------------------------------------------------------ AMERICAN HEART Heart Innovation 10/09/2014 $15,000.00 ASSOCIATION Forum ------------------------------------------------------------------------ MEDICAL SOCIETY OF NEW Medical Society of 10/09/2014 $2,500.00 JERSEY New Jersey 2015 Physician Advocacy Conference ------------------------------------------------------------------------ PEDIATRIC ENDOCRINE PES Parent, 10/13/2014 $50,000.00 SOCIETY Patient and Physician WEB Education Program for Lipodystrophy in Children, Adolescents, and Adults ------------------------------------------------------------------------ TRUSTEES OF THE 7th Focus on Lung 10/13/2014 $3,000.00 UNIVERSITY OF Cancer Conference PENNSYLVANIA and 4rd CANPrevent Lung Cancer ------------------------------------------------------------------------ SOCIETY FOR Merrill J. Egorin 10/13/2014 $10,000.00 TRANSLATIONAL ONCOLOGY Workshop in Cancer Therapeutics and Drug Development ------------------------------------------------------------------------ SOCIETY FOR The Oncologist CME 10/13/2014 $10,000.00 TRANSLATIONAL ONCOLOGY Online Journal Curriculum: Lung Cancer ------------------------------------------------------------------------ PERSONALIZED MEDICINE Integrating 10/15/2014 $5,000.00 COALITION Personalized Medicine into Health Care: Solutions Summit 2015 ------------------------------------------------------------------------ BIOMEDICAL SCIENCE Hope Scholarship 10/16/2014 $7,500.00 CAREERS PROGRAM 2015-2016 ------------------------------------------------------------------------ AMERICAN COLLEGE OF Fact vs Fact: The 10/21/2014 $25,000.00 CARDIOLOGY FOUNDATION Cholesterol Guidelines Debate ------------------------------------------------------------------------ A. WEBB ROBERTS CENTER The 41st Annual 10/22/2014 $5,000.00 OF BAYLOR HEALTH CARE Williamsburg SYSTEM, DALLAS Conference on Heart Disease ------------------------------------------------------------------------ NATIONAL ASSOCIATION OF COPD: What NPs in 10/22/2014 $20,000.00 NURSE PRACTITIONERS IN Women's Health WOMEN'S HEALTH Need to Know ------------------------------------------------------------------------ SOCIETY FOR THE SITC 29th Annual 10/22/2014 $10,000.00 IMMUNOTHERAPY OF Meeting CANCER ------------------------------------------------------------------------ DAIBETES TECHNOLOGY Diabetes 10/22/2014 $10,000.00 SOCIETY Technology Meeting 2014 ------------------------------------------------------------------------ AMERICAN ASSOCIATION OF 2014-2015 AAPS 10/30/2014 $45,000.00 PHARMACEUTICAL Sustaining SCIENTISTS Sponsorship ------------------------------------------------------------------------ AMERICAN PSYCHIATRIC APNA 28th Annual 10/30/2014 $5,000.00 NURSES ASSOCIATION Conference- Building Connections: PMH Nursing Perspectives ------------------------------------------------------------------------ PEDIATRIC ENDOCRINE PES Consensus 10/30/2014 $92,200.00 SOCIETY statement on the Management of Lipodystrophy in Children, Adolescents, and Adults ------------------------------------------------------------------------ LETTERS AND SCIENCES Ovarian Cancer-- 10/30/2014 $287,365.00 Evolution and Evidence of Emerging Strategies (ISSS) ------------------------------------------------------------------------ THE CVA MEDICAL Cardiovascular 11/02/2014 $5,000.00 EDUCATION FOUNDATION Update 2015 ------------------------------------------------------------------------ UNIVERSITY OF MICHIGAN Vaccines: Past, 11/04/2014 $10,000.00 Present, and Future ------------------------------------------------------------------------ SOCIETY OF TOXICOLOGY Society of 11/04/2014 $2,000.00 Toxicology Annual Meeting ------------------------------------------------------------------------ NATIONAL COMMISSION FOR CCMEP 11/04/2014 $10,000.00 THE CERTIFICATION OF Certification CME PROFESSIONALS Exam for Healthcare CE Professionals ------------------------------------------------------------------------ MEDSTAR WASHINGTON Cardiovascular 11/05/2014 $50,000.00 HOSPITAL CENTER Research Technologies CRT 2015 ------------------------------------------------------------------------ NATIONAL KIDNEY Primary Care 11/05/2014 $50,000.00 FOUNDATION Practitioner (PCP) Attitudes and Practices: Testing Type-2 Diabetic Patients for Chronic Kidney Disease (CKD) Survey ------------------------------------------------------------------------ AMERICAN DIABETES Pathway To Stop 11/07/2014 $2,500,000.00 ASSOCIATION Diabetes ------------------------------------------------------------------------ AMERICAN PHARMACISTS Optimizing the 11/10/2014 $11,250.00 ASSOCIATION Management of Acute Coronary Syndromes through the Transitions of Care ------------------------------------------------------------------------ TEMPLE UNIVERSITY 43rd Annual 11/10/2014 $5,000.00 Philadelphia Workshop on Hemostasis, Thrombosis and Atherosclerosis ------------------------------------------------------------------------ NOT-FOR-PROFIT HOSPITAL Recognizing and 11/11/2014 $3,400.00 CORPORATION Treating Acute Coronary Syndrome- Current Guideline Based Management ------------------------------------------------------------------------ CARDIOVASCULAR RESEARCH Chronic Total 11/11/2014 $10,000.00 FOUNDATION Occlusion Summit 2015: A Live Demonstration Course ------------------------------------------------------------------------ INTERNATIONAL IASLC 11/12/2014 $16,000.00 ASSOCIATION FOR THE International STUDY OF LUNG CANCER Mentorship Program ------------------------------------------------------------------------ INTERNATIONAL 15th Annual 11/12/2014 $25,000.00 ASSOCIATION FOR THE Targeted STUDY OF LUNG CANCER Therapies of Lung (IASLC) Cancer meeting ------------------------------------------------------------------------ AMERICAN HEART Scientific 11/13/2014 $30,000.00 ASSOCIATION, INC. Sessions 2014 Acute Coronary Syndrome Track ------------------------------------------------------------------------ THE JOHNS HOPKINS The Johns Hopkins 11/13/2014 $138,261.57 UNIVERSITY University Allergy and Clinical Immunology Fellowship Program ------------------------------------------------------------------------ REGENTS OF THE The 2nd Annual 11/16/2014 $5,000.00 UNIVERSITY OF UCLA Diabetes CALIFORNIA Symposium ------------------------------------------------------------------------ AMERICAN ASSOCIATION AACR Annual 11/17/2014 $50,000.00 FOR CANCER RESEARCH Meeting--2015 ------------------------------------------------------------------------ AMERICAN SOCIETY OF American Society 11/17/2014 $25,000.00 HEMATOLOGY of Hematolgoy Scholar Awards ------------------------------------------------------------------------ AMERICAN SOCIETY OF The American 11/17/2014 $25,000.00 HEMATOLOGY Society of Hematology's Bridge Award Program ------------------------------------------------------------------------ AMERICAN ACADEMY OF 2015 AAAAI Annual 11/18/2014 $30,000.00 ALLERGY, ASTHMA AND Meeting Allied IMMUNOLOGY (AAAAI) Health Programming ------------------------------------------------------------------------ AMERICAN PSYCHIATRIC Psychiatric 11/21/2014 $60,400.00 NURSES ASSOCIATION Nursing E Series: Bipolar Disorder Across the Lifespan ------------------------------------------------------------------------ AMERICAN ASSOCIATION OF New Paradigms in 12/01/2014 $2,500.00 CLINICAL the Practice of ENDOCRINOLOGISTS PR Endocrinology CHAPTER ------------------------------------------------------------------------ NATIONAL ASSOCIATION OF Improving Outcomes 12/01/2014 $25,000.00 MANAGED CARE through Evidence- PHYSICIANS Based Diagnosis and Management of Chronic Obstructive Pulmonary Disease (COPD) ------------------------------------------------------------------------ THE GYNECOLOGIC 3rd Semi Annual 12/02/2014 $10,000.00 ONCOLOGY GROUP Meeting of NRG ONCOLOGY (Formerly GOG, NSABP, RTOG) ------------------------------------------------------------------------ FLORIDA ALLERGY, ASTHMA Florida Allergy, 12/02/2014 $10,825.00 AND IMMUNOLOGY SOCIETY Asthma and Immunology Society 2015 Annual CME Conference ------------------------------------------------------------------------ INTERNATIONAL 16th World 12/02/2014 $200,000.00 ASSOCIATION FOR THE Conference on STUDY OF LUNG CANCER Lung Cancer--ISS (IASLC) Association fee ------------------------------------------------------------------------ NATIONAL ASSOCIATION OF Evidence-based 12/02/2014 $23,795.71 SCHOOL NURSES, INC. asthma care in schools ------------------------------------------------------------------------ THE METHODIST HOSPITAL Cardiovascular 12/03/2014 $15,000.00 Fellows' Bootcamp Laying the Foundation ------------------------------------------------------------------------ NATIONAL COMPREHENSIVE NCCN 20th Annual 12/03/2014 $85,000.00 CANCER NETWORK, INC. Conference General Session: Advancing the Standard of Cancer CareTM ------------------------------------------------------------------------ NATIONAL COMPREHENSIVE Advances in the 12/03/2014 $100,000.00 CANCER NETWORK, INC. Treatment of Ovarian and Cervical Cancers: Expert- Facilitated Small Group Discussions of Challenging Cases ------------------------------------------------------------------------ THE MOUNT SINAI Complex Coronary 12/03/2014 $10,000.00 HOSPITAL Cases ------------------------------------------------------------------------ JOHNS HOPKINS The Johns Hopkins 12/03/2014 $150,000.00 UNIVERSITY University School of Medicine eDiabetes Review Volume 2 ------------------------------------------------------------------------ ROME FOUNDATION Rome IV: The 12/04/2014 $100,000.00 Functional Gastrointestinal Disorders ------------------------------------------------------------------------ UNIVERSITY OF KENTUCKY 9th Platelet 12/04/2014 $10,000.00 COLLEGE OF MEDICINE Colloquium ------------------------------------------------------------------------ CONQUER CANCER 2015 Conquer 12/04/2014 $30,000.00 FOUNDATION OF THE Cancer Foundation AMERICAN SOCIETY OF of ASCO Merit CLINICAL ONCOLOGY Awards ------------------------------------------------------------------------ CONQUER CANCER 2015 Conquer 12/04/2014 $25,000.00 FOUNDATION OF THE Cancer Foundation AMERICAN SOCIETY OF of ASCO CLINICAL ONCOLOGY International Innovation Grant ------------------------------------------------------------------------ NATIONAL COMPREHENSIVE 2015 Annual 12/04/2014 $10,000.00 CANCER NETWORK NCCN Nursing Program: Advancing Oncology Nursing at the 20th NCCN Annual Conference ------------------------------------------------------------------------ NATIONAL COMPREHENSIVE 2015 NCCN Oncology 12/04/2014 $10,000.00 CANCER NETWORK, INC. Fellows Program: New Horizons in Quality Cancer Care at the 20th Annual Conference ------------------------------------------------------------------------ STENO DIABETES CENTER A/ 28th European 12/04/2014 $20,000.00 S Diabetic Nephropathy Study Group Annual Meeting ------------------------------------------------------------------------ AMERICAN SOCIETY OF Improving Patient 12/04/2014 $110,000.00 HEALTH-SYSTEM Outcomes: PHARMACISTS Maximizing the Role of the GLP-1 Based Therapies in Our Patients with Type 2 Diabetes ------------------------------------------------------------------------ ENDOCRINE SOCIETY ENDO 2015 Thyroid 12/04/2014 $55,000.00 Sessions ------------------------------------------------------------------------ UNIVERSITY OF TEXAS XVI Curso 12/07/2014 $10,000.00 SOUTHWESTERN MEDICAL Intensivo de CENTER Diabetes, Endocrinologia y Enfermedades Metabolicas ------------------------------------------------------------------------ AMERICAN ASSOCIATION OF Advances in 12/07/2014 $10,000.00 CLINICAL Medical and ENDOCRINOLOGISTS Surgical Management of Thyroid Cancer ------------------------------------------------------------------------ AMERICAN PAIN SOCIETY 2015 Fundamentals 12/07/2014 $35,000.00 of Pain Management: An Interdisciplinary Primer ------------------------------------------------------------------------ HEMATOLOGY/ONCOLOGY 2015 HOPA 11th 12/07/2014 $25,000.00 PHARMACY ASSOCIATION Annual Conference ------------------------------------------------------------------------ LUMEN FOUNDATION Lumen Global 2015 12/08/2014 $75,000.00 ------------------------------------------------------------------------ NATIONAL ASSOCIATION OF Mentoring Program 12/08/2014 $10,000.00 NEONATAL NURSES Toolkit for Novice Nurse Practitioners ------------------------------------------------------------------------ CONQUER CANCER 2015 Conquer 12/08/2014 $250,000.00 FOUNDATION OF THE Cancer Foundation AMERICAN SOCIETY OF of ASCO Career CLINICAL ONOCLOGY Development Award (CDA) ------------------------------------------------------------------------ CONQUER CANCER 2015 Conquer 12/08/2014 $10,500.00 FOUNDATION OF THE Cancer Foundation AMERICAN SOCIETY OF of ASCO CLINICAL ONCOLOGY International Development and Education Award (IDEA) ------------------------------------------------------------------------ THE ENDOCRINE SOCIETY Applying the 12/08/2014 $525,980.00 Evidence for GLP- 1 Receptor Agonists in Type 2 Diabetes: Practice Perspectives ------------------------------------------------------------------------ FORCE--FACING OUR RISK Joining FORCEs 12/08/2014 $50,000.00 OF CANCER EMPOWERED Against Hereditary Cancer Conference ------------------------------------------------------------------------ AMERICAN COLLEGE OF Lipid Management 12/08/2014 $50,000.00 CARDIOLOGY FOUNDATION Today: Unanswered Questions and Unquestioned Answers--Live Clinical Focus Session at ACC.15 ------------------------------------------------------------------------ AMERICAN PHARMACISTS Access to Care: 12/09/2014 $11,250.00 ASSOCIATION Addressing Health Literacy in Diabetes ------------------------------------------------------------------------ THE ENDOCRINE SOCIETY Diabetes Diagnosis 12/09/2014 $50,000.00 and Management 2015 ------------------------------------------------------------------------ ENDOCRINE SOCIETY Endocrine Fellows 12/09/2014 $70,000.00 Conference: Type 1 Diabetes Care and Management ------------------------------------------------------------------------ CLINICAL AND PATIENT Clinical Issues in 12/09/2014 $368,966.00 EDUCATORS ASSOCIATION Type 2 Diabetes: Discussions and Debates Around GLP-1 Receptor Agonists ------------------------------------------------------------------------ AMERICAN COLLEGE OF ACCs 64th Annual 12/09/2014 $100,000.00 CARDIOLOGY FOUNDATION Scientific Session--ACC.15 Acute Coronary Syndromes Clinical Learning Pathway ------------------------------------------------------------------------ CONQUER CANCER 2015 Conquer 12/10/2014 $60,000.00 FOUNDATION OF THE Cancer Foundation AMERICAN SOCIETY OF Young CLINICAL ONCOLOGY Investigator Award ------------------------------------------------------------------------ ENDOCRINE SOCIETY Diabetes Masters 12/10/2014 $235,867.00 Series 2015 : Solving the Puzzle: Putting the Pieces Together to Provide Quality T2DM Care ------------------------------------------------------------------------ CONQUER CANCER 2015 ASCO Annual 12/10/2014 $112,000.00 FOUNDATION OF THE Meeting Lung AMERICAN SOCIETY OF Cancer Track CLINICAL ONCOLOGY ------------------------------------------------------------------------ INSTITUTE FOR MEDICAL Who s on First? 12/10/2014 $316,029.80 AND NURSING EDUCATION What s on Second? Identifying a Line-up of Newer Agents to Individualize Care for Your Patient with T2DM ------------------------------------------------------------------------ PENNSYLVANIA STATE Controlling Severe 12/11/2014 $236,659.94 UNIVERSITY Asthma Today and Tomorrow ------------------------------------------------------------------------ CHILDREN'S HOSPITAL 2015 Weinstein 12/11/2014 $5,000.00 CORPORATION Cardiovascular Development Conference ------------------------------------------------------------------------ NATIONAL COMPREHENSIVE 2015-2016 Monthly 12/11/2014 $35,000.00 CANCER NETWORK, INC Oncology Tumor Boards: A Multidisciplinary Approach to Individualized Patient Care ------------------------------------------------------------------------ ENDOCRINE SOCIETY ENDO 2015 Diabetes 12/14/2014 $30,000.00 Sessions ------------------------------------------------------------------------ AMERICAN ASSOCIATION OF Case Challenges in 12/14/2014 $181,705.00 CLINICAL T2D: Applying the ENDOCRINOLOGISTS AACE Algorithm to Practice ------------------------------------------------------------------------ THE CHEST FOUNDATION The CHEST 12/15/2014 $180,000.00 Foundation COPD Research Grant Program ------------------------------------------------------------------------ JOSLIN DIABETES CENTER, SGLT-2 Inhibitors 12/15/2014 $321,885.00 INC. in Type 2 Diabetes: Incorporating New Approaches Into Practice Through an Interdisciplinary Exploration ------------------------------------------------------------------------ AMERICAN OSTEOPATHIC The Path to Better 12/15/2014 $263,394.54 ASSOCIATION T2DM Outcomes, A Coordinated Approach to Patient-centered Care ------------------------------------------------------------------------ UNIVERSITY OF Optimizing 12/21/2014 $62,825.00 CINCINNATI Outcomes in Type 2 Diabetes: Integrating Longer Acting GLP- 1 Receptor Agonists ------------------------------------------------------------------------ RICHMOND UNIVERSITY Treatment- 12/22/2014 $1,100.00 MEDICAL CENTER Refractory Gout ------------------------------------------------------------------------ DUKE UNIVERSITY SCHOOL Regional Systems 01/04/2015 $3,500,000.00 OF MEDICINE Accelerator: Implementation of The American Heart Associations Mission: Lifeline- AMI Discharge and Follow Up Demonstration Project ------------------------------------------------------------------------ AMERICAN COLLEGE OF You Say Do, I Say 01/06/2015 $150,000.00 CARDIOLOGY FOUNDATION Don t: Controversial Debates in ACS-- Live Clinical Focus Session at ACC.15 ------------------------------------------------------------------------ AMERICAN COLLEGE OF ACC.15 Prevention 01/07/2015 $75,000.00 CARDIOLOGY FOUNDATION Learning Pathway ------------------------------------------------------------------------ AMERICAN HEART American Heart 01/08/2015 $2,000,000.00 ASSOCIATION, INC. Association Cardiovascular Genome Phenome Study (CV-GPS) ------------------------------------------------------------------------ AMERICAN HEART American Heart 01/11/2015 $6,000,000.00 ASSOCIATION, INC. Association s Guideline Transformation and Optimization (GTO) Program ------------------------------------------------------------------------ CARDIOVASCULAR RESEARCH Post Conference 01/14/2015 $100,000.00 FOUNDATION CME Webcast Series 2015 ------------------------------------------------------------------------ GASTROINTESTINAL AND The 2015 US GI and 01/14/2015 $35,000.00 LIVER ASSOCIATION OF Liver Association THE AMERICAS (GALA) of the Americas (GALA) Conference Series ------------------------------------------------------------------------ AMERICAN COLLEGE OF ACCs 64th Annual 01/14/2015 $25,000.00 CARDIOLOGY FOUNDATION Scientific Session (ACC.15) TCT@ACC-i2 Learning Pathway ------------------------------------------------------------------------ GORDON RESEARCH 2015 Gordon 01/14/2015 $5,000.00 CONFERENCES Research Conference on the Molecular and Cellular Biology of Lipids ------------------------------------------------------------------------ GEORGIA ASSOCIATION OF Cardiology Track-- 01/14/2015 $5,000.00 PHYSICIAN ASSISTANTS How PAs Can Impact Patient Outcomes Across Cardiovascular Diseases (Part of GAPA 2015 Spring Conference) ------------------------------------------------------------------------ AMERICAN ASSOCIATION OF Endocrine 01/15/2015 $5,000.00 CLINICAL University: ENDOCRINOLOGISTS Disease Management and Technology Skills for Fellows-in- Training (Thyroid Module) ------------------------------------------------------------------------ UNIVERSITY OF TEXAS 16th Annual 01/15/2015 $3,000.00 HEALTH SCIENCE CENTER Practical SAN ANTONIO SCHOOL OF Applications of MEDICINE New Agents in Oncology ------------------------------------------------------------------------ NATIONAL LIPID National Lipid 01/15/2015 $15,000.00 ASSOCIATION Association 2015 Lipid Academy ------------------------------------------------------------------------ NATIONAL LIPID 2015 Masters in 01/15/2015 $15,000.00 ASSOCIATION Lipidology ------------------------------------------------------------------------ EMORY UNIVERSITY Atlanta Clinical 01/18/2015 $15,000.00 Cardiology Update ------------------------------------------------------------------------ SOCIETY FOR SCAI 2015 01/27/2015 $85,000.00 CARDIOVASCULAR Scientific ANGIOGRAPHY AND Sessions INTERVENTIONS ------------------------------------------------------------------------ ENDOCRINE SOCIETY Thyroid Endocrine 01/28/2015 $10,000.00 Self-Assessment Program 2015 ------------------------------------------------------------------------ SCRIPPS HEALTH Scripps 35th 01/29/2015 $5,000.00 Annual Conference: Clinical Hematology and Oncology 2015 ------------------------------------------------------------------------ NORTHEASTERN UNIVERSITY Boston Symposium 01/29/2015 $2,500.00 on Organic and Bioorganic Chemistry (BSOBC) ------------------------------------------------------------------------ CARDIOVASCULAR RESEARCH ACS/STEMI: Focus 01/29/2015 $60,000.00 FOUNDATION on Acute Care at SCAI 2015 ------------------------------------------------------------------------ NATIONAL ASSOCIATION OF Exploring Optimal 01/29/2015 $25,000.00 MANAGED CARE Antiplatelet PHYSICIANS Therapies in the Management of Acute Coronary Syndrome (ACS) ------------------------------------------------------------------------ CARDIOVASCULAR RESEARCH 21st Annual 01/29/2015 $25,000.00 FOUNDATION Interventional Cardiology Fellows Course ------------------------------------------------------------------------ UNIVERSITY OF FLORIDA Vascular Biology 01/29/2015 $15,000.00 Working Group US Chapter Meeting ------------------------------------------------------------------------ IOWA PHYSICIAN Update on Lipid 01/29/2015 $6,500.00 ASSISTANT SOCIETY Management ------------------------------------------------------------------------ PREVENTIVE Cardiovascular 02/01/2015 $25,000.00 CARDIOVASCULAR NURSES Risk Reduction: ASSOCIATION Leading the Way in Prevention (21st Annual Symposium) ------------------------------------------------------------------------ PRIMARY CARE NETWORK, Are Gout Goals 02/02/2015 $619,095.00 INC. Achievable? The Provider/ Patient Alliance ------------------------------------------------------------------------ PREVENTIVE PCNA-Triglycerides 02/02/2015 $179,540.00 CARDIOVASCULAR NURSES ASSOCIATION ------------------------------------------------------------------------ NATIONAL LIPID National Lipid 02/02/2015 $120,000.00 ASSOCIATION Association 2015 Scientific Meeting Series ------------------------------------------------------------------------ AMERICAN HEART Chest Pain 02/02/2015 $15,000.00 ASSOCIATION Coordinator Boot Camp ------------------------------------------------------------------------ THE BOARD OF REGENTS OF Cardiovascular 02/08/2015 $5,000.00 THE UNIVERSITY OF Medicine and WISCONSIN SYSTEM Prevention Update for Primary Care ------------------------------------------------------------------------ UNIVERSITY OF KANSAS 6th Expert 02/09/2015 $5,000.00 MEDICAL CENTER Strategies in Endoscopy, Gastrointestinal and Liver Disorders ------------------------------------------------------------------------ TRUSTEES OF THE 2nd Cardiovascular 02/11/2015 $5,000.00 UNIVERSITY OF Symposium PENNSYLVANIA/CME ------------------------------------------------------------------------ AMERICAN PHARMACISTS APhA2015 Rise in 02/11/2015 $22,500.00 ASSOCIATION Oral Oncologic Medications Creates New Challenges in Adherence ------------------------------------------------------------------------ EMORY UNIVERSITY EPIC SEC Emory 02/11/2015 $25,000.00 Practical Intervention Course Southeast Consortium ------------------------------------------------------------------------ NATIONAL COMPREHENSIVE Advances in the 02/11/2015 $232,693.00 CANCER NETWORK Treatment of Ovarian and Cervical Cancers: Expert- Facilitated Small Group Discussions of Challenging Cases ------------------------------------------------------------------------ REGENTS OF THE Moores Cancer 02/12/2015 $3,000.00 UNIVERSITY OF Center 11th CALIFORNIA Industry/Academia Translational Oncology Symposium ------------------------------------------------------------------------ SCRIPPS HEALTH The Future of 02/12/2015 $10,000.00 Genomic Medicine VIII ------------------------------------------------------------------------ DELAWARE ACADEMY OF Hyperlipidemia 02/12/2015 $2,780.00 PHYSICIAN ASSISTANTS ------------------------------------------------------------------------ THE MASSACHUSETTS 29th Harvard 02/17/2015 $5,000.00 GENERAL HOSPITAL Critical Issues in Tumor Microenvironment: Angiogenesis Metastasis and Immunology Course ------------------------------------------------------------------------ KERN ASPEN LIPID Emerging Therapies 02/17/2015 $10,000.00 CONFERENCE for Cardiovascular Diseases: A Dialogue Between Academic and Pharmaceutical Research ------------------------------------------------------------------------ FLORIDA ASSOCIATION OF Acute Coronary 02/17/2015 $8,325.00 CONSULTANT PHARMACISTS Syndrome; Strategies to Optimize Transitions in Care and Reduce Readmissions ------------------------------------------------------------------------ ST. JOSEPH'S REGIONAL COPD 02/18/2015 $1,900.00 MEDICAL CENTER ------------------------------------------------------------------------ CARDIOVASCULAR RESEARCH Issues with DAPT 02/18/2015 $50,000.00 FOUNDATION Series 2015 ------------------------------------------------------------------------ NURSE PRACTITIONER The Challenges of 02/19/2015 $5,000.00 ASSOCIATES FOR Asthma and COPD CONTINUING EDUCATION in Primary Care (NPACE) ------------------------------------------------------------------------ NORTHWESTERN UNIVERSITY The 8th Annual 02/19/2015 $2,500.00 Womens Cardiovascular Health Symposium ------------------------------------------------------------------------ AMERICAN HEART Atlanta Mission: 02/19/2015 $2,500.00 ASSOCIATION Lifeline Meeting ------------------------------------------------------------------------ AMERICAN ASSOCIATION OF How to Talk to 02/22/2015 $231,590.00 NURSE PRACTITIONERS Your Patients about Opioid- induced Constipation: A Dialogue about New Advances ------------------------------------------------------------------------ AMERICAN THYROID American Thyroid 02/22/2015 $25,000.00 ASSOCIATION Association Satellite Symposium: ATA Guidelines on Medullary Thyroid Cancer and Pediatric Thyroid Cancer Highlights, Controversies a ------------------------------------------------------------------------ THOMAS JEFFERSON 3rd Annual 02/22/2015 $3,000.00 UNIVERSITY Jefferson Lung Cancer Symposium 2015 ------------------------------------------------------------------------ AMERICAN COLLEGE OF What's New in 02/22/2015 $95,085.00 CHEST PHYSICIANS Asthma/COPD Syndrome ------------------------------------------------------------------------ WEST PENN ALLEGHENY Cardiovascular 02/22/2015 $10,000.00 HEALTH SYSTEM Medicine Update 2015 ------------------------------------------------------------------------ AMERICAN DIABETES 62nd Annual 02/23/2015 $10,000.00 ASSOCIATION Advanced Postgraduate Course 2015 ------------------------------------------------------------------------ SOCIETY OF GYNECOLOGIC SGO Annual Meeting 02/23/2015 $50,000.00 ONCOLOGY on Women's Cancer ------------------------------------------------------------------------ BAYLOR UNIVERSITY The 18th Annual 02/23/2015 $3,000.00 MEDICAL CENTER DBA A. Tyler Breast WEBB ROBERTS CENTER Cancer Conferecne 2015 ------------------------------------------------------------------------ PENNSYLVANIA ACADEMY OF PAFP/F Live and 02/23/2015 $5,000.00 FAMILY PHYSICIANS Enduring CME FOUNDATION Primary and Secondary Prevention of ASCVD ------------------------------------------------------------------------ ONCOLOGY NURSING Oncology Nursing 02/23/2015 $25,000.00 SOCIETY Society 40th Annual Congress ------------------------------------------------------------------------ AMERICAN ASSOCIATION OF 2015-2016 AAPS 02/23/2015 $50,000.00 PHARMACEUTICAL Sustaining SCIENTISTS Sponsorship ------------------------------------------------------------------------ ASPEN LUNG CONFERENCE Thomas L. Petty 02/24/2015 $15,000.00 Aspen Lung Conference:Asthma 2015: Mechanisms to Personalized Medicine ------------------------------------------------------------------------ ST. FRANCIS HOSPITAL-- Intravascular 02/26/2015 $7,000.00 U.S. CATHOLIC Coronary Imaging CONFERENCE and Physiology 2015: A Clinical Workshop ------------------------------------------------------------------------ NATIONAL ASSOCIATION OF NAPNAP Conference 02/26/2015 $7,500.00 PEDIATRIC NURSE Sponsorship PRACTITIONERS ------------------------------------------------------------------------ AMERICAN ASSOCIATION 95th Annual 02/26/2015 $10,000.00 FOR THORACIC SURGERY Meeting American Association for Thoracic Surgery ------------------------------------------------------------------------ NATIONAL KIDNEY Session Support: 02/26/2015 $20,000.00 FOUNDATION INC. CKD MANAGEMENT ALONG THE CONTINUUM: FROM PREDIALYSIS TO POLICY ------------------------------------------------------------------------ CITY OF HOPE NATIONAL 15th Annual 03/01/2015 $5,000.00 MEDICAL CENTER Rachmiel Levine Diabetes and Obesity Symposium ------------------------------------------------------------------------ AMERICAN THORACIC ATS 2015 03/01/2015 $25,000.00 SOCIETY International Conference, Fellows Track Symposium ------------------------------------------------------------------------ AMERICAN THORACIC 2015 International 03/01/2015 $10,000.00 SOCIETY ATS Conference--Selec ted Topics in Asthma ------------------------------------------------------------------------ NATIONAL JEWISH HEALTH Improving the 03/01/2015 $10,000.00 Quality of Care for Patients with Asthma ------------------------------------------------------------------------ ST. JOSEPH'S REGIONAL Year in Review in 03/01/2015 $3,700.00 MEDICAL CENTER Acute Coronary Syndromes ------------------------------------------------------------------------ THE BOARD OF REGENTS OF COPD9USA 03/02/2015 $40,000.00 THE UNIVERSITY OF NEBRASKA DBA THE UNIVERSITY OF NEBRASKA MEDICAL CENTER ------------------------------------------------------------------------ AMERICAN THORACIC ATS 2015 03/02/2015 $72,919.82 SOCIETY International Conference--Selec ted Topics in COPD ------------------------------------------------------------------------ NATIONAL JEWISH HEALTH Best Practices in 03/02/2015 $72,161.00 Managing Patients with COPD: Emerging Therapies and Patient Education Strategies ------------------------------------------------------------------------ CARDIOVASCULAR RESEARCH DAPT Dilemmas: A 03/02/2015 $69,100.00 FOUNDATION Case-Based Roundtable Tutorial ------------------------------------------------------------------------ ALZHEIMER'S ASSOCIATION 2015 Alzheimers 03/02/2015 $50,000.00 Association Research Roundtable ------------------------------------------------------------------------ CONQUER CANCER 2015 ASCO Annual 03/02/2015 $56,000.00 FOUNDATION OF THE Meeting AMERICAN SOCIETY OF Gynecologic CLINICAL ONCOLOGY Cancer Track: Scientific and Educational Program ------------------------------------------------------------------------ AMERICAN ACADEMY OF AAPA Conference 03/02/2015 $5,000.00 PHYSICIAN ASSISTANTS 2015--CardiologyT rack ------------------------------------------------------------------------ PREVENTIVE The Post-ACS 03/04/2015 $100,000.00 CARDIOVASCULAR NURSES Patient: ASSOCIATION Adherence to Critical Therapies in the Short- and Long- Term ------------------------------------------------------------------------ NATIONAL ASSOCIATION OF 2015 Charitable 03/04/2015 $30,000.00 FREE AND CHARITABLE Health Care CLINICS Education and Training Symposium ------------------------------------------------------------------------ GORDON RESEARCH High Throughput 03/04/2015 $2,500.00 CONFERENCES Chemistry and Chemical Biology ------------------------------------------------------------------------ NEW YORK ACADEMY OF Non-Motor 03/04/2015 $2,000.00 SCIENCES Symptoms: Unraveling the ``Invisible'' Face of Parkinson s Disease ------------------------------------------------------------------------ SOCIETY FOR PHYSICIAN SPAP's 9th Annual 03/08/2015 $1,500.00 ASSISTANTS IN Conference PEDIATRICS ------------------------------------------------------------------------ JDRF INTERNATIONAL TypeOneNation 03/08/2015 $4,500.00 Research Summit ------------------------------------------------------------------------ GORDON RESEARCH Solving Knowledge 03/08/2015 $3,000.00 CONFERENCE Gaps in Drug Metabolism and Pharmacokinetic Prediction, Improving Translational Medicine ------------------------------------------------------------------------ NURSE PRACTITIONER Clinical Pearls in 03/09/2015 $2,500.00 ASSOCIATES FOR Managing Diabetes CONTINUING EDUCATION in 2015 (NPACE) ------------------------------------------------------------------------ PRESIDENT AND FELLOWS Cardiovascular 03/09/2015 $11,500.00 OF HARVARD COLLEGE Medicine 2015: Updates for the Practitioner ------------------------------------------------------------------------ AMERICAN ASSOCIATION OF Diabetes Sessions 03/10/2015 $25,000.00 CLINICAL at Endocrine ENDOCRINOLOGISTS University: Disease Management and Technology Skills for Endocrinology Fellows in Training ------------------------------------------------------------------------ NEBRASKA ACADEMY OF Gout 2015 03/10/2015 $1,500.00 PHYSICIAN ASSISTANTS ------------------------------------------------------------------------ NATIONAL COMPREHENSIVE NCCN 2015 Oncology 03/10/2015 $20,000.00 CANCER NETWORK, INC. 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Meeting ------------------------------------------------------------------------ CONQUER CANCER 2015 ASCO Annual 03/18/2015 $84,000.00 FOUNDATION OF THE Meeting Breast AMERICAN SOCIETY OF Cancer Track: CLINICAL ONCOLOGY Scientific and Educational Program ------------------------------------------------------------------------ AMERICAN COLLEGE OF Diabetes is 03/19/2015 $15,000.00 OSTEOPATHIC FAMILY Primary PHYSICIANS Addressing Primary Care Clinical Gaps in Diabetes Management by Partnering With Experts ------------------------------------------------------------------------ MERCY HEALTH SYSTEM Care Transitions 03/19/2015 $5,000.00 SEPA Conference ------------------------------------------------------------------------ THE MEDICAL UNIVERSITY 10th Annual 03/19/2015 $5,000.00 OF SOUTH CAROLINA Symposium entitled the Nephrology Update for Primary Care and Hospital Medicine ------------------------------------------------------------------------ ALZHEIMER'S ASSOCIATION 2015 Alzheimer's 03/23/2015 $95,000.00 Association International Conference ------------------------------------------------------------------------ SOCIETY FOR 2015 Annual 03/23/2015 $25,000.00 TRANSLATIONAL ONCOLOGY Meeting ------------------------------------------------------------------------ SWEDISH MEDICAL CENTER Thyroid Cancer and 03/24/2015 $3,000.00 FOUNDATION Parathyroid Disease--A Practical Approach ------------------------------------------------------------------------ ASSOCIATION OF WOMEN'S AWHONN Annual 03/24/2015 $7,500.00 HEALTH, OBSTETRIC AND Convention NEONATAL NURSES (AWHONN) ------------------------------------------------------------------------ GORDON RESEARCH 2015 Proteins 03/24/2015 $3,000.00 CONFERENCES Gordon Conference ------------------------------------------------------------------------ AMERICAN ASSOCIATION OF AACE 24th Annual 03/25/2015 $30,000.00 CLINICAL Scientifc and ENDOCRINOLOGISTS Clinical Congress (Diabetes portion) ------------------------------------------------------------------------ THE ASSOCIATION FOR AFTD's Annual 03/25/2015 $1,000.00 FRONTOTEMPORAL Education DEGENERATION (AFTD) Conference ------------------------------------------------------------------------ TRINITAS REGIONAL Lung Cancer 03/25/2015 $1,750.00 MEDICAL CENTER ------------------------------------------------------------------------ INSTITUTE FOR PATIENT 2015 Premature 03/25/2015 $125,000.00 ACCESS Infant Health Summit ------------------------------------------------------------------------ SOCIETY FOR Young Investigator 03/25/2015 $25,000.00 NEUROSCIENCE Award ------------------------------------------------------------------------ ST. DOMINIC--JACKSON STOP STEMI and 03/25/2015 $25,000.00 MEMORIAL HOSPITAL STOP STROKE program by Pulsara ------------------------------------------------------------------------ AMERICAN ASSOCIATION Anti-cancer Drug 03/26/2015 $10,000.00 FOR CANCER RESEARCH Action and Drug Resistance: ------------------------------------------------------------------------ YALE UNIVERSITY 2015 New England 03/26/2015 $3,000.00 Thyroid Club Program ------------------------------------------------------------------------ AMERICAN ASSOCIATION OF AACE 24th Annual 03/26/2015 $25,000.00 CLINICAL Scientific and ENDOCRINOLOGISTS Clinical Congress (Thyroid sessions) ------------------------------------------------------------------------ CLEVELAND CLINIC Cleveland Breast 03/26/2015 $5,000.00 EDUCATIONAL FOUNDATION Cancer 2015: Collaborating For A Cure ------------------------------------------------------------------------ OKLAHOMA HEART RESEARCH 26th Annual Update 03/26/2015 $2,500.00 AND EDUCATION in Cardiology FOUNDATION ------------------------------------------------------------------------ CEDARS-SINAI MEDICAL 3rd Annual 03/29/2015 $5,000.00 CENTER Experimental Therapeutics in Oncology: The Road to Personalized Medicine ------------------------------------------------------------------------ CASE MANAGEMENT SOCIETY CMSA 2015 03/29/2015 $15,000.00 OF AMERICA Conference and Expo ------------------------------------------------------------------------ SOCIETY FOR SCAI Complex 03/29/2015 $15,000.00 CARDIOVASCULAR Peripheral ANGIOGRAPHY AND Vascular INTERVENTIONS Interventions FOUNDATION Course ------------------------------------------------------------------------ AMERICAN COLLEGE OF Bringing Science 03/29/2015 $50,000.00 CARDIOLOGY FOUNDATION to Clinical Practice: Best of ACC 2015 ------------------------------------------------------------------------ ICAHN SCHOOL OF Live Symposium of 03/29/2015 $10,000.00 MEDICINE AT MOUNT Complex Coronary SINAI Valvular and Vascular Cases ------------------------------------------------------------------------ ASOCIACION Metabolic Syndrome 03/30/2015 $1,500.00 PUERTORRIQUENA DE Update: GRADUADOS DE Challenges in UNIVERSIDADES Preventive ESPANOLAS-APGUE Medicine ------------------------------------------------------------------------ UNIVERSITY OF Breast Symposium 03/30/2015 $3,250.00 PITTSBURGH 2015: Updates in the Management of Breast Cancer/ Breast Disease ------------------------------------------------------------------------ JOHNS HOPKINS 6th Annual Johns 03/30/2015 $2,500.00 UNIVERSITY Hopkins Cardiovascular Research Retreat ------------------------------------------------------------------------ SOCIETY FOR VASCULAR Society for 03/30/2015 $5,000.00 MEDICINE Vascular Medicine 26th Annual Scientific Sessions ------------------------------------------------------------------------ NURSE PRACTITIONER Updates in COPD 03/30/2015 $3,200.00 ASSOCIATES FOR 2015 CONTINUING EDUCATION (NPACE) ------------------------------------------------------------------------ THE CHRIST HOSPITAL The FETCH 03/31/2015 $5,000.00 Conference ------------------------------------------------------------------------ THE CHEST FOUNDATION The CHEST 03/31/2015 $30,000.00 Foundation Lung Cancer Clinical Research Grant Program ------------------------------------------------------------------------ NEW YORK MEDICAL Systemic Treatment 03/31/2015 $2,500.00 COLLEGE of Lung Cancer ------------------------------------------------------------------------ THE CENTER OF 8th Annual 03/31/2015 $5,000.00 EXCELLENCE IN Cardiovascular EDUCATION Update- A Practical Tutorial ------------------------------------------------------------------------ ST. JOSEPH'S HOSPITAL 4th Annual Arizona 04/01/2015 $15,000.00 AND MEDICAL CENTER Diabetes Series: Focus on Treatment Advances, Patient- Centered Care, Obesity and Other Comorbidities ------------------------------------------------------------------------ THE UNIVERSITY OF TEXAS Annual Meeting of 04/01/2015 $5,000.00 MD ANDERSON CANCER the Felix CENTER Rutledge Society ------------------------------------------------------------------------ GOUT AND URIC ACID Gout and Uric Acid 04/01/2015 $70,000.00 EDUCATION SOCIETY Education Society Roundtable: Elevating the Severity of Gout and Improving Access to Public Education and Treatment ------------------------------------------------------------------------ VIVA PHYSICIANS VIVA 15: Vascular 04/01/2015 $20,000.00 InterVentional Advances ------------------------------------------------------------------------ UNIVERSITY OF University of 04/02/2015 $20,000.00 WASHINGTON Washington Allergy and Immunology Fellowship ------------------------------------------------------------------------ WASHINGTON ACADEMY OF 26th Annual 04/06/2015 $1,500.00 PHYSICIAN ASSISTANTS Recertification Review Course and Spring Conference ------------------------------------------------------------------------ CLEVELAND CLINIC Advances in Lung 04/07/2015 $5,000.00 EDUCATIONAL FOUNDATION Cancer: A Multidisciplinary Approach ------------------------------------------------------------------------ FEDERATION OF AMERICAN Molecular, 04/08/2015 $10,000.00 SOCIETIES FOR Structural and EXPERIMENTAL BIOLOGY Clinical Aspects of VK and VK- Dependent Proteins ------------------------------------------------------------------------ FEDERATION OF AMERICAN FASEB conference 04/08/2015 $5,000.00 SOCIETIES FOR on Genetic EXPERIMENTAL BIOLOGY Recombination and Genome Rearrangements ------------------------------------------------------------------------ SCRIPPS WHITTIER Emerging 04/09/2015 $30,000.00 DIABETES INSTITUTE Therapeutic Trends to Optimize Diabetes Care ------------------------------------------------------------------------ AMERICAN COLLEGE OF 2015 04/09/2015 $5,000.00 CARDIOLOGY FOUNDATION Interventional Cardiology Board Preparatory Course ------------------------------------------------------------------------ AMERICAN FEDERATION FOR 2015 Eastern 04/12/2015 $2,500.00 MEDICAL RESEARCH Regional Meeting of the American Federation for Medical Research ------------------------------------------------------------------------ PONCE MEDICAL SCHOOL Overcoming 04/12/2015 $10,000.00 FOUNDATION INC. Obstacles to Reduce Acute Coronary Syndrome ------------------------------------------------------------------------ SOUTH CAROLINA ASTHMA Midlands Regional 04/12/2015 $3,000.00 ALLIANCE Asthma Conference ------------------------------------------------------------------------ PHARMACY QUALITY Measuring What 04/13/2015 $12,500.00 ALLIANCE (PQA, INC.) Matters: Improving Care and Driving the Next Generation of Performance Measures ------------------------------------------------------------------------ METABOLIC ENDOCRINE The Comprehensive 04/13/2015 $283,155.00 EDUCATION FOUNDATION Management of DM-- Focus on SGLT2 Inhibitors and Combination Therapy--Emerging Concepts of Renal Effects ------------------------------------------------------------------------ ASTHMA AND ALLERGY Wheezin', Sneezin' 04/14/2015 $5,000.00 FOUNDATION OF AMERICA, and Itchin' in ALASKA CHAPTER Alaska ------------------------------------------------------------------------ NATIONAL ASSOCIATION OF Individualizing 04/14/2015 $25,000.00 MANAGED CARE Treatment PHYSICIANS, INC. Strategies to Improve Patient Outcomes in the Management of Type 2 Diabetes (T2DM) ------------------------------------------------------------------------ MIDMICHIGAN MEDICAL Valley Diabetes 04/15/2015 $2,500.00 CENTER--MIDLAND Symposium ------------------------------------------------------------------------ TRUSTEES OF BOSTON Opioid Induced 04/15/2015 $117,200.00 UNIVERSITY DBA BOSTON Constipation: A UNIVERSITY SCHOOL OF Neglected MEDICINE Complication ------------------------------------------------------------------------ PARTNERS HEALTHCARE World Medical 04/15/2015 $50,000.00 SYSTEM Innovation Forum ------------------------------------------------------------------------ MASSACHUSETTS INSTITUTE CANCER COMPLEXITY: 04/15/2015 $5,000.00 OF TECHNOLOGY Heterogeneity in Tumor Progression and Drug Response ------------------------------------------------------------------------ AMERICAN SOCIETY OF ASN Kidney Week-- 04/16/2015 $55,000.00 NEPHROLOGY CKD Learning Pathway Support ------------------------------------------------------------------------ NATIONAL ASSOCIATION Leading Care 04/19/2015 $15,000.00 FOR HEALTHCARE QUALITY Transitions: Improving Quality in Safety Across the Healthcare Continuum ------------------------------------------------------------------------ FEDERATION OF AMERICAN 12th FASEB Summer 04/19/2015 $7,000.00 SOCIETIES FOR Research EXPERIMENTAL BIOLOGY Conference on ``Proteases in Hemostasis and Vascular Biology'' ------------------------------------------------------------------------ AMERICAN SOCIETY FOR ASPMN 25th 04/20/2015 $20,000.00 PAIN MANAGEMENT National NURSING Conference ------------------------------------------------------------------------ REGENTS OF THE 5th International 04/20/2015 $3,000.00 UNIVERSITY OF Symposium on Lung- CALIFORNIA Sparing Therapies for Malignant Pleural Mesothelioma ------------------------------------------------------------------------ GORDON RESEARCH 2015 Medicinal 04/20/2015 $3,000.00 CONFERENCES Chemistry Gordon Research Conference ------------------------------------------------------------------------ AMERICAN THORACIC ATS 2015 04/21/2015 $50,000.00 SOCIETY International Conference--Selec ted Topics in Lung Cancer ------------------------------------------------------------------------ OKLAHOMA UNIVERSITY 18th Annual 04/21/2015 $1,500.00 HEALTH SCIENCES CENTER Primary Care Update 2015 Asthma ------------------------------------------------------------------------ OKLAHOMA UNIVERSITY 18th Annual 04/21/2015 $1,500.00 HEALTH SCIENCE CENTER Primary Care COLLEGE OF MEDICINE Update 2015- Ovarian Cancer ------------------------------------------------------------------------ REGENTS OF THE LIPID MAPS 04/21/2015 $7,500.00 UNIVERSITY OF Meeting: CALIFORNIA Lipidomics Impact on Cancer, Metabolic and Inflammatory Diseases ------------------------------------------------------------------------ CARDIOVASCULAR RESEARCH Knights of the 04/21/2015 $50,000.00 FOUNDATION Roundtable 2015: Challenging AMI Therapies ------------------------------------------------------------------------ HOUSTON METHODIST Cardiovascular 04/21/2015 $15,000.00 HOSPITAL Fellows' Bootcamp- Laying the Foundation ------------------------------------------------------------------------ UNIVERSITY OF Seventh Annual 04/22/2015 $3,250.00 PITTSBURGH Multidisciplinary Thyroid Cancer Symposium: Integrating the New ATA Guidelines into Clinical Practice ------------------------------------------------------------------------ AMERICAN ASSOCIATION OF 36th Annual 04/22/2015 $3,000.00 ENDOCRINE SURGEONS Meeting of the American Association of Endocrine Surgeons ------------------------------------------------------------------------ DUKE UNIVERSITY HEALTH Closing the Gap on 04/22/2015 $20,000.00 SYSTEM Medication Management, Discharge Preparedness and Readmissions ------------------------------------------------------------------------ CLEVELAND CLINIC ASCO Review 04/23/2015 $3,000.00 EDUCATIONAL FOUNDATION ------------------------------------------------------------------------ SWEDISH MEDICAL CENTER Annual Oncology 04/23/2015 $3,000.00 FOUNDATION Symposium: Personalized Medicine--Genetic Testing, Targeted Molecular Therapy and WHole Patient Care ------------------------------------------------------------------------ OKLAHOMA UNIVERSITY 18th Annual 04/23/2015 $1,500.00 HEALTH SCIENCE CENTER Primary Care COLLEGE OF MEDICINE Update: COPD ------------------------------------------------------------------------ WASHINGTON UNIVERSITY Update on 04/23/2015 $4,000.00 Gynecologic Cancer ------------------------------------------------------------------------ WASHINGTON UNIVERSITY Cardiology Update 04/23/2015 $4,000.00 SCHOOL OF MEDICINE, ST. LOUIS ------------------------------------------------------------------------ NEW YORK ACADEMY OF Emerging 04/27/2015 $5,000.00 SCIENCES Approaches to Cancer Immunotherapy ------------------------------------------------------------------------ LYMPHOMA RESEARCH Lymphoma Research 04/27/2015 $15,000.00 FOUNDATION Foundation Immune Checkpoint Inhibitor Workshop ------------------------------------------------------------------------ YALE UNIVERSITY Yale Cancer Center 04/28/2015 $5,000.00 Oncology Series-- 2015 ------------------------------------------------------------------------ MOUNT CARMEL HEALTH 2015 ASCO REVIEW 04/28/2015 $3,000.00 SYSTEM ------------------------------------------------------------------------ COLUMBIA UNIVERSITY Breast Cancer 04/28/2015 $3,000.00 DEPARTMENT OF SURGERY Management 2015 ------------------------------------------------------------------------ NORTHWESTERN UNIVERSITY 4th Annual Chicago 04/28/2015 $6,000.00 Cardiovascular Update ------------------------------------------------------------------------ DIGNITY HEALTH ST. 17th Annual 04/29/2015 $6,000.00 BERNARDINE MEDICAL Cardiac CENTER Symposium: Advances in Cardiovascular Disease 2015 ------------------------------------------------------------------------ GORDON RESEARCH 2015 Gordon 04/29/2015 $2,500.00 CONFERENCES Conference on Heterocyclic Compounds ------------------------------------------------------------------------ INTERNATIONAL SOCIETY Regulatory and 04/29/2015 $2,500.00 FOR COMPUTATIONAL Systems Genomics, BIOLOGY INC. with DREAM Challenges Conference ------------------------------------------------------------------------ YALE UNIVERSITY Yale ASCO Review 04/30/2015 $3,000.00 2015 ------------------------------------------------------------------------ UNIVERSITY OF VERMONT OBESITY AND 04/30/2015 $5,000.00 AND STATE AGRICULTURAL METABOLISM: An COLLEGE Emerging Frontier in Lung Health and Disease ------------------------------------------------------------------------ SWEDISH MEDICAL CENTER The Transradial 04/30/2015 $5,000.00 FOUNDATION Approach: A Case- based and Hands- on Training Course ------------------------------------------------------------------------ MONTEFIORE MEDICAL Achieving Balance: 05/03/2015 $161,500.00 CENTER Practical Management Strategies for Opioid-Induced Constipation ------------------------------------------------------------------------ CALIFORNIA SOCIETY OF CSAAI 23rd Annual 05/05/2015 $3,000.00 ALLERGY, ASTHMA, AND Educational IMMUNOLOGY Meeting ------------------------------------------------------------------------ TRUSTEES OF THE Advanced Thyroid 05/06/2015 $5,000.00 UNIVERSITY OF Master Class PENNSYLVANIA ------------------------------------------------------------------------ CANCER MOLECULAR Molecular 05/06/2015 $5,000.00 THERAPEUTICS RESEARCH Therapeutics of ASSOCIATION Cancer Conference, 2015 ------------------------------------------------------------------------ NORTH SHORE LONG ISLAND Post American 05/07/2015 $3,000.00 JEWISH HEALTH SYSTEM Society of INC. Clinical Oncology 2015 ------------------------------------------------------------------------ AMERICAN COLLEGE OF Update in Allergy, 05/12/2015 $5,000.00 ALLERGY, ASTHMA AND Asthma and IMMUNOLOGY Immunology ------------------------------------------------------------------------ ALBERT EINSTEIN Complex 05/14/2015 $5,000.00 HEALTHCARE NETWORK Angioplasty Symposium Exchange Philadelphia ------------------------------------------------------------------------ SOCIETY FOR The Oncologist CME 05/17/2015 $10,000.00 TRANSLATIONAL ONCOLOGY Online Journal Curriculum: Breast Cancer ------------------------------------------------------------------------ ANENBERG CENTER FOR PosterPerspectives 05/18/2015 $25,000.00 HEALTH SCIENCES AT : Research EISENHOWER Developments in NSCLC / 2015 ASCO ------------------------------------------------------------------------ WESTERN ASSOCIATION Hitting the 05/18/2015 $12,500.00 GYNECOLOGIOC targets in ONCOLOGISTS Gynecologic Cancer ------------------------------------------------------------------------ AMERICAN THYROID ATA Early Riser 05/19/2015 $129,500.00 ASSOCIATION Symposium: New Modalities to Treat Medullary Thyroid Cancer ------------------------------------------------------------------------ CARDIOVASCULAR RESEARCH Issues with DAPT: 05/19/2015 $25,000.00 FOUNDATION A Case-based Roundtable with the Experts ------------------------------------------------------------------------ LAHEY CLINIC HOSPITAL, Cardiovascular 05/19/2015 $6,000.00 INC. Disease State of the Art 2015 ------------------------------------------------------------------------ AMERICAN COLLEGE OF ACC Cardiovascular 05/19/2015 $5,000.00 CARDIOLOGY FOUNDATION Board Review for Certification and Recertification ------------------------------------------------------------------------ CANCER RESEARCH Immunotherapy for 05/19/2015 $75,000.00 INSTITUTE the Oncology Nurse ------------------------------------------------------------------------ GORDON RESEARCH Gordon Research 05/20/2015 $5,000.00 CONFERENCES Conference; Hormone dependent cancer ------------------------------------------------------------------------ NORTHEASTERN UNIVERSITY Boston Symposium 05/21/2015 $3,500.00 on Organic and Bioorganic Chemistry (BSOBC) ------------------------------------------------------------------------ AMERICAN SOCIETY OF Anemia, 05/21/2015 $190,000.00 NEPHROLOGY Erythropoeisis, and the Nephrologist ------------------------------------------------------------------------ CANCER RESEARCH 2015 International 05/24/2015 $50,000.00 INSTITUTE Cancer Immunotherapy Conference ------------------------------------------------------------------------ ZOE ROSE MEMORIAL 2015 Preemie 05/24/2015 $10,000.00 FOUNDATION Parent Summit ------------------------------------------------------------------------ THE GOG FOUNDATION INC 4th Semi Annual 05/26/2015 $20,000.00 Meeting of NRG Oncology (formerly GOG, NSABP, RTOG) ------------------------------------------------------------------------ CLINICAL CARE OPTIONS Immunotherapy for 05/26/2015 $25,000.00 Cancer Track: CCO Independent Conference Highlights of the 2015 ASCO Annual Meeting ------------------------------------------------------------------------ ACADEMIA MEDICA DEL SUR Non-Small Cell 05/26/2015 $3,000.00 Lung Cancer: Current Therapy and Promising New Regimens ------------------------------------------------------------------------ AMERICAN ANMS 10th 05/26/2015 $6,400.00 NEUROGASTROENTEROLOGY Postgraduate AND MOTILITY SOCIETY Course in Gastroenterology and Neurogastroentero logy in Clinical Practice ------------------------------------------------------------------------ CEO ROUNDTABLE ON Prostate Cancer 05/27/2015 $30,000.00 CANCER, INC. DREAM Challenge Winning Teams Educational Grant ------------------------------------------------------------------------ C-CHANGE Big Data in Cancer 05/27/2015 $25,000.00 Care ------------------------------------------------------------------------ THE GOG FOUNDATION Rational 05/27/2015 $10,000.00 Combination Targeted Therapies for Gynecologic Cancers ------------------------------------------------------------------------ TRUSTEES OF COLUMBIA Lung Cancer 2015: 05/27/2015 $3,000.00 UNIVERSITY IN THE CITY New Discoveries, OF NEW YORK New Directions ------------------------------------------------------------------------ NOT-FOR-PROFIT HOSPITAL Lung Cancer 05/27/2015 $1,900.00 CORPORATION Screening in 2015 ------------------------------------------------------------------------ OLIGONUCLEOTIDE 11th Annual 05/31/2015 $7,500.00 THERAPEUTICS SOCIETY Meeting of the Oligonucleotide Therapeutics Society ------------------------------------------------------------------------ CONQUER CANCER 2015 Best of ASCO 05/31/2015 $15,000.00 FOUNDATION OF THE Meetings AMERICAN SOCIETY OF CLINICAL ONCOLOGY ------------------------------------------------------------------------ AMERICAN ASSOCIATION OF Improving Outcomes 06/02/2015 $101,800.00 DIABETES EDUCATORS for Women With Type 2 Diabetes Individualizing Evidence-Based Care ------------------------------------------------------------------------ NATIONAL KIDNEY Chronic Kidney 06/02/2015 $75,000.00 FOUNDATION Disease and the Primary Care Practitioner: ------------------------------------------------------------------------ UNIVERSITY OF MARYLAND 17th Annual 06/02/2015 $15,000.00 BALTIMORE FOUNDATION, International INC. Meeting of the Institute of Human Virology ------------------------------------------------------------------------ TRUSTEES OF THE 2015 Updates in 06/03/2015 $5,000.00 UNIVERSITY OF Oncology: With PENNSYLVANIA Proceedings from International Medical Meetings ------------------------------------------------------------------------ MELANOMA RESEARCH Melanoma Research 06/03/2015 $112,280.00 FOUNDATION Foundation CURE OM Junior Fellowship ------------------------------------------------------------------------ AMERICAN OSTEOPATHIC Optimizing Anti- 06/04/2015 $357,790.00 ASSOCIATION platelet Therapy and Secondary Prevention Strategies in Acute Coronary Syndromes The Role of the Primary Care Practice (150203494) ------------------------------------------------------------------------ INTERNATIONAL SOCIETY Workshop on 06/09/2015 $30,000.00 FOR STEM CELL RESERACH Clinical Translation ------------------------------------------------------------------------ NURSE PRACTITIONER The Latest in 06/10/2015 $5,000.00 ASSOCIATES FOR Asthma and COPD CONTINUING EDUCATION (NPACE) ------------------------------------------------------------------------ AMERICAN PHARMACISTS IMPACT Care 06/10/2015 $74,987.00 ASSOCIATION FOUNDATION Transformation Institute ------------------------------------------------------------------------ AMERICAN ASSOCIATION Advances in Breast 06/11/2015 $10,000.00 FOR CANCER RESEARCH Cancer Research ------------------------------------------------------------------------ AMERICAN ASSOCIATION Advances in 06/11/2015 $10,000.00 FOR CANCER RESEARCH Ovarian Cancer Research ------------------------------------------------------------------------ AMERICAN COLLEGE OF Symposium--Asthma, 06/11/2015 $50,000.00 ALLERGY, ASTHMA AND COPD and Asthma- IMMUNOLOGY COPD Overlap Syndrome (ACOS) ------------------------------------------------------------------------ CASE MANAGEMENT SOCIETY Improving 06/11/2015 $6,265.00 OF AMERICA Medication Adherence in the COPD Patient through Greater Patient Engagement ------------------------------------------------------------------------ AMERICAN ASSOCIATION OF California Chapter 06/16/2015 $20,000.00 CLINICAL of the American ENDOCRINOLOGISTS Association of Clinical Endocrinologists Presents: Hot Topics in Diabetes and Endocrinology for Primary Care ------------------------------------------------------------------------ FLORIDA ACADEMY OF Update on COPD and 06/16/2015 $4,300.00 PHYSICIAN ASSISTANTS Asthma Management INC. ------------------------------------------------------------------------ AMERICAN ACADEMY OF 2015 AAFP FMX 06/16/2015 $13,000.00 FAMILY PHYSICIANS Assembly 60 Minute Lecture titled Acute Coronary Syndrome and Angina ------------------------------------------------------------------------ AMERICAN COLLEGE OF ACEP Pediatric 06/17/2015 $2,500.00 EMERGENCY PHYSICAINS Emergency Medicine Special Interest Section Annual Meeting ------------------------------------------------------------------------ FOUNDATION FOR FGO Genetics 06/18/2015 $35,000.00 GYNECOLOGIC ONCOLOGY Summit ------------------------------------------------------------------------ FRIENDS OF CANCER 2015 Friends of 06/22/2015 $100,000.00 RESEARCH Cancer Research Programs ------------------------------------------------------------------------ DIVISION OF MEDICINAL Division of 06/23/2015 $2,500.00 CHEMISTRY Medicinal Chemistry Program American Chemical Society 250th National Meeting ------------------------------------------------------------------------ RECTOR AND VISITORS OF Vasculata 2015 06/24/2015 $10,000.00 THE UNIVERSITY OF VIRGINIA ------------------------------------------------------------------------ AMERICAN COLLEGE OF Preventing 06/24/2015 $48,000.00 CHEST PHYSICIANS Exacerbations of COPD ------------------------------------------------------------------------ ASSOCIATION OF ASTHMA The Asthma Team: 06/24/2015 $5,000.00 EDUCATORS Making Wishes Come True ------------------------------------------------------------------------ THE MASSACHUSETTS 30th Annual 06/24/2015 $5,000.00 GENERAL HOSPITAL Critical Issues In Tumor Microenvironment: Angiogenesis, Metastasis and Immunology ------------------------------------------------------------------------ NATIONAL MEDICAL The National 06/24/2015 $3,000.00 ASSOCIATION Medical Association Asthma Update: Evidence-Based Diagnosis and management of Asthma--Practical Tools to Improve Patient Care ------------------------------------------------------------------------ NATIONAL ASSOCIATION OF Reducing 06/25/2015 $12,500.00 MANAGED CARE Exacerbations in PHYSICIANS the Treatment and Management of Chronic Obstructive Pulmonary Disease (COPD) ------------------------------------------------------------------------ ONCOLOGY NURSING Pharmacology 06/30/2015 $15,000.00 SOCIETY Updates in Oncology Practice Conference ------------------------------------------------------------------------ UC BERKELEY FOUNDATION IGI CRISPR 06/30/2015 $10,000.00 Workshop: Routes to Designer Biology ------------------------------------------------------------------------ METABOLIC ENDOCRINE 13th Annual World 07/01/2015 $100,000.00 EDUCATION FOUNDATION Congress on Insulin Resistance Diabetes and Cardiovascular Disease--WCIRDC ------------------------------------------------------------------------ PARTNERS HEALTHCARE 2015 Personalized 07/02/2015 $25,000.00 PERSONALIZED MEDICINE Medicine Conference ------------------------------------------------------------------------ NATIONAL ASSOCIATION OF Improving Patient 07/02/2015 $25,000.00 MANAGED CARE Outcomes with PHYSICIANS, INC. Novel Treatments in the Management of Hypertriglyceride mia ------------------------------------------------------------------------ NEW YORK CITY SOCIETY Practical 07/07/2015 $9,500.00 OF HEALTH- SYSTEM considerations PHARMACISTS for using novel oral antiplatelet agents in patients with acute coronary syndromes ------------------------------------------------------------------------ INTERNATIONAL EGFR Diagnostic 07/09/2015 $201,000.00 ASSOCIATION FOR THE Expert Consensus STUDY OF LUNG CANCER meeting ------------------------------------------------------------------------ UB FOUNDATION Recent Advances in 07/09/2015 $2,500.00 ACTIVITIES, INC. the pathophysiology and management of type 2 diabetes ------------------------------------------------------------------------ AMERICAN PHARMACISTS APhA's Pharmacist 07/14/2015 $25,000.00 ASSOCIATION and Patient Centered Diabetes Care Certificate Training Program National Offerings ------------------------------------------------------------------------ AMERICAN ASSOCIATION AACR-NCI-EORTC 07/14/2015 $25,000.00 FOR CANCER RESEARCH Molecular Targets and Cancer Therapeutics ------------------------------------------------------------------------ JOHNS HOPKINS Mid-Atlantic 07/14/2015 $49,381.58 UNIVERSITY SCHOOL OF Nephrology Young MEDICINE Investigators' Forum ------------------------------------------------------------------------ SOUTH DAKOTA ACADEMY OF COPD: diagnosis 07/14/2015 $3,500.00 PHYSICIAN ASSISTANTS and optimum treatment ------------------------------------------------------------------------ SOUTHERN SOCIETY FOR 15th Annual SSCI 07/15/2015 $43,940.49 CLINICAL INVESTIGATION Nephrology Young Investigators' Forum ------------------------------------------------------------------------ YALE UNIVERSITY 2015 London 07/16/2015 $5,000.00 Cardiovascular Device Innovation Summit ------------------------------------------------------------------------ REGENTS OF THE Updates in 07/19/2015 $5,000.00 UNIVERSITY OF Rheumatology 2015 CALIFORNIA ------------------------------------------------------------------------ REGENTS OF THE 13th Annual 07/21/2015 $34,698.53 UNIVERSITY OF Nephrology Young CALIFORNIA Investigator's Forum ------------------------------------------------------------------------ SOCIETY FOR 2015 SITC 07/22/2015 $50,000.00 IMMUNOTHERAPY OF International CANCER Symposium on Cancer Immunotherapy ------------------------------------------------------------------------ SOCIETY FOR SITC 2015 Global 07/22/2015 $25,000.00 IMMUNOTHERAPY OF Regulatory Summit CANCER ------------------------------------------------------------------------ NATIONAL COMPREHENSIVE NCCN/SCCA 2015 07/26/2015 $10,000.00 CANCER NETWORK, INC. Thoracic Oncology Symposium ------------------------------------------------------------------------ SOCIETY FOR Named Postdoctoral 07/26/2015 $120,000.00 IMMUNOTHERAPY OF Cancer CANCER Immunotherapy in NSCLC Clinical Fellowship Award ------------------------------------------------------------------------ NATIONAL ASSOCIATION Gout: Bridging 07/26/2015 $163,946.00 FOR CONTINUING Knowledge Gaps in EDUCATION Diagnosis and Treatment ------------------------------------------------------------------------ NATIONAL COMPREHENSIVE 2015 NCCN Immuno- 07/26/2015 $35,000.00 CANCER NETWORK, INC. 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Individualized Treatment Strategies in the Management of Advanced Non Small-Cell Lung Cancer (NSCLC) ------------------------------------------------------------------------ HACKENSACK UNIVERSITY Fifth Annual Heart 08/03/2015 $5,000.00 MEDICAL CENTER and Vascular Symposium ------------------------------------------------------------------------ METABOLIC ENDOCRINE Early Intervention 08/06/2015 $149,515.00 EDUCATION FOUNDATION in The Continuum of Hyperglycemia-- The Role of Initial Combination Therapy ------------------------------------------------------------------------ SOCIETY FOR Primer on Tumor 08/10/2015 $15,000.00 IMMUNOTHERAPY OF Immunology and CANCER Cancer Immunotherapy ------------------------------------------------------------------------ NATIONAL COMPREHENSIVE NCCN/SCCA 2015 08/11/2015 -$2,005.40 CANCER NETWORK, INC. Thoracic Oncology Symposium ------------------------------------------------------------------------ CONQUER CANCER 2015 Breast Cancer 08/11/2015 $10,000.00 FOUNDATION OF THE Symposium: AMERICAN SOCIETY OF Enhancing CLINICAL ONCOLOGY Clinical Care through Collaboration ------------------------------------------------------------------------ AMERICAN ACADEMY OF Management of 08/11/2015 $242,009.00 FAMILY PHYSICIANS Gout: Individualizing the Approach ------------------------------------------------------------------------ BREATHE CALIFORNIA OF Advancing the 08/16/2015 $3,000.00 LOS ANGELES COUNTY diagnosis and management of COPD with a focus on COPD exacerbations ------------------------------------------------------------------------ GLOBAL ACADEMY FOR 8th Annual 08/17/2015 $35,000.00 MEDICAL EDUCATION Perspectives in Rheumatic Diseases presented by Rheumatology News, Internal Medicine News, Family Practice News ------------------------------------------------------------------------ NORTHWESTERN UNIVERSITY 17th Annual Lynn 08/17/2015 $10,000.00 Sage Breast Cancer Symposium ------------------------------------------------------------------------ AMERICAN COLLEGE OF Cardiovascular 08/17/2015 $10,000.00 EMERGENCY PHYSICIANS Disease Track at ACEP 2015 Scientific Assembly ------------------------------------------------------------------------ NATIONAL ASSOCIATION OF NANN 31st Annual 08/19/2015 $10,000.00 NEONATAL NURSES Educational Conference ------------------------------------------------------------------------ UNIVERSITY OF 2nd Annual 08/19/2015 $25,000.00 CINCINNATI Cincinnati Collaborative Cardiovascular Symposium (C4) ------------------------------------------------------------------------ AMERICAN ASSOCIATION OF AACE/ACE 08/20/2015 $99,804.71 CLINICAL Scientific and ENDOCRINOLOGISTS Clinical Review of DKA and the Effects of SGLT2 Inhibitors ------------------------------------------------------------------------ AMERICAN COLLEGE OF TAS: Allergy, 08/23/2015 $1,000.00 ALLERGY, ASTHMA AND Asthma and IMMUNOLOGY Immunology Conference ------------------------------------------------------------------------ NAMI MARYLAND NAMI Maryland 2015 08/25/2015 $5,000.00 Annual Education Conference ------------------------------------------------------------------------ CONNECTICUT PHARMACISTS Insights, Pearls, 08/25/2015 $5,000.00 ASSOCIATION and Perspectives-- An Update in the Management of Chronic Obstructive Pulmonary Disease ------------------------------------------------------------------------ AMERICAN COLLEGE OF Plenary Session-- 08/25/2015 $50,000.00 ALLERGY, ASTHMA AND Updates in Severe IMMUNOLOGY Asthma ------------------------------------------------------------------------ UNIVERSITY OF FLORIDA Vascular Biology 08/26/2015 $10,000.00 Working Group Global Chapter Meeting ------------------------------------------------------------------------ PENN STATE UNIVERSITY Skin, Bones, 08/26/2015 $5,000.00 Hearts and Private Parts ------------------------------------------------------------------------ AMERICAS HEALTH Roundtable 08/27/2015 $37,462.15 FOUNDATION Discussion on Decreasing the Burden of Influenza in Latin America ------------------------------------------------------------------------ DANA-FARBER CANCER 11th Annual 08/27/2015 $2,500.00 INSTITUTE INC. 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Meeting ------------------------------------------------------------------------ PHARMACY QUALITY Getting to the 10/05/2015 $3,500.00 ALLIANCE (PQA, INC) Core: Building and Implementing Core Measures ------------------------------------------------------------------------ BAYLOR UNIVERSITY Immune Checkpoint 10/07/2015 $5,000.00 MEDICAL CENTER Inhibitors in the Treatment of Selected Tumor Types: A New Prospective ------------------------------------------------------------------------ CEDARS SINAI MEDICAL 4th Annual New 10/07/2015 $5,000.00 CENTER Therapeutics in Oncology: The Road to Personalized Medicine ------------------------------------------------------------------------ PENN STATE UNIVERSITY Skin, Bones, 10/07/2015 $5,000.00 Hearts and Private Parts (two conferences) ------------------------------------------------------------------------ INDIANA UNIVERSITY Performance 10/07/2015 $5,000.00 Improvement with Point of Care Clinical Decision Making App in non- ST segment elevation myocardial infarction (NSTEMI) patients ------------------------------------------------------------------------ MEDSTAR WASHINGTON Update In 10/08/2015 $15,000.00 HOSPITAL CENTER Rheumatology 2015: New Diagnostic Tests and Treatments for Clinical Practice ------------------------------------------------------------------------ NEW YORK STATE New York State 10/08/2015 $2,500.00 OSTEOPATHIC MEDICAL Osteopathic SOCIETY Medical Students Health Policy Initiative ------------------------------------------------------------------------ THE UNIVERSITY OF TEXAS 2015 Oncologic 10/11/2015 $5,000.00 MD ANDERSON CANCER Emergency CENTER Medicine Conference ------------------------------------------------------------------------ AMERICAN PANCREATIC 46th Annual 10/11/2015 $10,000.00 ASSOCIATION Meeting of the American Pancreatic Association ------------------------------------------------------------------------ WAYNE STATE UNIVERSITY 2nd Annual Update 10/15/2015 $3,000.00 SCHOOL OF MEDICINE in Rheumatology ------------------------------------------------------------------------ WAYNE STATE UNIVERSITY State of the Art 10/15/2015 $3,000.00 Management of Lung Cancer Symposium ------------------------------------------------------------------------ MEDICAL UNIVERSITY OF 2nd Annual 10/18/2015 $10,000.00 SOUTH CAROLINA Comprehensive Stroke and Cerebrovascular Update ------------------------------------------------------------------------ AMERICAN COLLEGE OF 2015 10/19/2015 $25,000.00 RHEUMATOLOGY Musculoskeletal Ultrasound Course for Rheumatologists ------------------------------------------------------------------------ LOUISIANA STATE LSUHSC 10/20/2015 $3,500.00 UNIVERSITY HEALTH Cardiovascular SCIENCES CENTER IN NEW Centers Joint ORLEANS Retreat ------------------------------------------------------------------------ AMERICAN ASSOCIATION OF Achieving 10/20/2015 $389,000.00 DIABETES EDUCATORS Partnerships and Improving Outcomes in Your Diabetes Patients ------------------------------------------------------------------------ THE ENDOCRINE SOCIETY The Truth of the 10/21/2015 $284,438.73 Matter: An Evidence-Based Review of the Newer Antihyperglycemic Agents for T2DM: a hot seat Program ------------------------------------------------------------------------ GORDON RESEARCH 2016 Basal Ganglia 10/21/2015 $2,500.00 CONFERENCES Gordon Research Conference: Emerging Views of Cellular and Circuit Diversity Within the Basal Ganglia ------------------------------------------------------------------------ MEDSTAR WASHINGTON Lung Cancer 2015: 10/22/2015 $3,000.00 HOSPITAL CENTER A Shifting Management Paradigm with ------------------------------------------------------------------------ NATIONAL QUALITY FORUM NQF Measure 10/22/2015 $100,000.00 Incubator ------------------------------------------------------------------------ GORDON RESEARCH 2016 Gordon 10/26/2015 $2,500.00 CONFERENCES Research Conference on Heterocyclic Compounds ------------------------------------------------------------------------ AMERICAN HEART Scientific 10/26/2015 $30,000.00 ASSOCIATION, INC. 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Series: Breast Cancer ------------------------------------------------------------------------ AMERICAN SOCIETY FOR 2016 12/10/2015 $10,000.00 RADIATION ONCOLOGY Multidisciplinary Head and Neck Cancer Symposium ------------------------------------------------------------------------ NATIONAL COMPREHENSIVE NCCN 21st Annual 12/10/2015 $75,000.00 CANCER NETWORK, INC. Conference General Session: Advancing the Standard of Cancer CareTM ------------------------------------------------------------------------ AMERICAN ASSOCIATION AACR Annual 12/10/2015 $125,000.00 FOR CANCER RESEARCH Meeting--2016 ------------------------------------------------------------------------ AMERICAN FEDERATION FOR 2016 Southern 12/10/2015 $5,000.00 MEDICAL RESEARCH Regional Meeting ------------------------------------------------------------------------ NATIONAL COMPREHENSIVE NCCN 2016 Nursing 12/13/2015 $25,000.00 CANCER NETWORK, INC. Program: Advancing Oncology Nursing at the NCCN 21st Annual Conference ------------------------------------------------------------------------ INTERNATIONAL 16th Targeted 12/13/2015 $82,500.00 ASSOCIATION FOR THE Therapy meeting STUDY OF LUNG CANCER on Lung Cancer ------------------------------------------------------------------------ AMERICAN Opioid-Induced 12/13/2015 $192,601.00 GASTROENTEROLOGICAL Constipation: ASSOCIATION Recognition and Optimal Management ------------------------------------------------------------------------ KANAWHA COUNTY Mobile Integrated 12/14/2015 $50,000.00 EMERGENCY AMBULANCE Health Program: AUTHORITY Emphasis on Community Paramedicine ------------------------------------------------------------------------ INTERNATIONAL PDL1 Atlas 12/14/2015 $120,000.00 ASSOCIATION FOR THE STUDY OF LUNG CANCER ------------------------------------------------------------------------ CONQUER CANCER 2016 Conquer 12/15/2015 $500,000.00 FOUNDATION OF THE Cancer Foundation AMERICAN SOCIETY OF of the American CLINICAL ONCOLOGY Society of Clinical Oncology Mission Endowment ------------------------------------------------------------------------ CATAMOUNT MEDICAL PatientGPS : 12/16/2015 $74,841.86 EDUCATION, LLC Clinical Paths in the Management of Patients with COPD ------------------------------------------------------------------------ AMERICAN PHARMACISTS APhA 2016 Hot 12/16/2015 $20,000.00 ASSOCIATION Topics in Dyslipidemia ------------------------------------------------------------------------ THE SCRIPPS RESEARCH 27th Annual 12/16/2015 $1,500.00 INSTITUTE Frontiers in Chemistry Symposium at The Scripps Research Institute ------------------------------------------------------------------------ NATIONAL COMPREHENSIVE Behind the 12/17/2015 $10,000.00 CANCER NETWORK, INC. Guidelines: Insights into the Standard of Care in Oncology 2016 ------------------------------------------------------------------------ NATIONAL COMPREHENSIVE NCCN 2016 Oncology 12/17/2015 $25,000.00 CANCER NETWORK, INC. Fellows Program: New Horizons in Quality Cancer Care at the NCCN 21st Annual Conference ------------------------------------------------------------------------ NATIONAL LIPID National Lipid 12/17/2015 $30,000.00 ASSOCIATION Association 2016 Scientific Meeting Series ------------------------------------------------------------------------ PEDIATRIC INFECTIOUS Pediatric 12/20/2015 $55,000.00 DISEASES SOCIETY Infectious EDUCATION AND RESEARCH Diseases Society FOUNDATION (PIDSERF) Fellowship Awards Program ------------------------------------------------------------------------ THE VANDERBILT Cardiology 2016: 12/20/2015 $5,000.00 UNIVERSITY Advances in Science and Practice ------------------------------------------------------------------------ FOUNDATION FOR Quality 12/22/2015 $20,000.00 CONTINUING EDUCATION Improvement IN THE HEALTH Education (QIE) PROFESSIONS Initiative National Training and Education ------------------------------------------------------------------------ MARYLAND SOCIETY FOR Update on Gout and 01/04/2016 $1,625.00 THE RHEUMATIC DISEASES Pseudogout ------------------------------------------------------------------------ THE GOG FOUNDATION 5th Semi Annual 01/05/2016 $20,000.00 Meeting of NRG Oncology (formerly GOG, NSABP,RTOG) ------------------------------------------------------------------------ CEDARS-SINAI MEDICAL The James R. 01/05/2016 $5,000.00 CENTER Klinenberg, MD Symposium on Rheumatic Diseases: Hot Topics in Rheumatology ------------------------------------------------------------------------ LUNGEVITY FOUNDATION LUNGevity 01/06/2016 $25,000.00 Foundation Scientific and Clinical Research Roundtable ------------------------------------------------------------------------ CARDIOVASCULAR RESEARCH Chronic Total 01/07/2016 $10,000.00 FOUNDATION Occlusion Summit 2016 ------------------------------------------------------------------------ LUMEN FOUNDATION Lumen Global 2016 01/10/2016 $35,000.00 ------------------------------------------------------------------------ CARDIOVASCULAR RESEARCH St. Francis 01/10/2016 $5,000.00 FOUNDATION Imaging Course 2016 ------------------------------------------------------------------------ AMERICAN HEART Epidemiology and 01/12/2016 $10,000.00 ASSOCIATION, INC. Prevention--Lifes tyle and Cardiometabolic Health 2016 Scientific Sessions ------------------------------------------------------------------------ CLEVELAND CLINIC Beyond 01/14/2016 $22,696.65 EDUCATIONAL FOUNDATION Revascularization for CLI-The Role of Pharmacotherapy Satellite Symposium ------------------------------------------------------------------------ CARDIOVASCULAR CVIs 4th Annual 01/14/2016 $2,500.00 INSTITUTE OF Interventional PHILADELPHIA Cardiovascular Medicine: The Crossroads of Interventional and Clinical Cardiology ------------------------------------------------------------------------ UNIVERSITY OF TENNESSEE Testing to Target 01/19/2016 $288,885.00 COLLEGE OF PHARMACY in Non-Small Cell Lung Cancer: Managed Care Perspectives ------------------------------------------------------------------------ SOCIETY FOR VASCULAR Society for 01/20/2016 $20,000.00 MEDICINE Vascular Medicine 27th Annual Scientific Sessions ------------------------------------------------------------------------ OHIOHEALTH 1st Bi-Annual 01/20/2016 $2,500.00 OhioHealth Acute Cardiovascular Care Conference ------------------------------------------------------------------------ SOCIETY FOR Immunotherapy of 01/24/2016 $40,000.00 IMMUNOTHERAPY OF Cancer for the CANCER Workshop on Biomarkers ------------------------------------------------------------------------ NORTHEAST GEORGIA 8th Annual 01/25/2016 $2,500.00 MEDICAL CENTER INC. Northeast Georgia Regional STEMI Summit ------------------------------------------------------------------------ CALIFORNIA THORACIC COPD: A TEAM 01/26/2016 $5,000.00 SOCIETY APPROACH ------------------------------------------------------------------------ CARDIOVASCULAR RESEARCH Issues with DAPT: 01/28/2016 $50,000.00 FOUNDATION A case-based guide to optimal antiplatelet therapies ------------------------------------------------------------------------ GASTROINTESTINAL AND The 2016 US GI and 01/28/2016 $16,000.00 LIVER ASSOCIATION OF Liver Association THE AMERICAS INC. of the Americas (GALA) Conference Series ------------------------------------------------------------------------ GORDON RESEARCH 2016 Lipoprotein 01/28/2016 $5,000.00 CONFERENCES Metabolism Gordon Research Conference and Gordon Research Seminar ------------------------------------------------------------------------ AMERICAN ACADEMY OF AAPM 32nd Annual 01/31/2016 $25,000.00 PAIN MEDICINE Meeting 2016 ------------------------------------------------------------------------ DUKE UNIVERSITY DCRI Evidence to 02/01/2016 $10,000.00 Practice Series: Interventional Cardiology ------------------------------------------------------------------------ AMERICAN COLLEGE OF ACCs 65th Annual 02/01/2016 $50,000.00 CARDIOLOGY FOUNDATION Scientific Session (ACC.16) Acute Coronary Syndromes Clinical Learning Pathway ------------------------------------------------------------------------ REGENTS OF THE LIPID MAPS 02/01/2016 $5,000.00 UNIVERSITY OF Meeting: CALIFORNIA Lipidomics Impact on Metabolic, Cancer, Cardiovascular and Inflammatory Diseases ------------------------------------------------------------------------ SCOTTSDALE HEALTHCARE 2016 Scottsdale 02/02/2016 $2,500.00 FOUNDATION Interventional Forum (SIF 2016) ------------------------------------------------------------------------ UNIVERSITY OF FLORIDA Vascular Biology 02/02/2016 $15,000.00 Working Group U.S. Chapter Meeting ------------------------------------------------------------------------ EMORY UNIVERSITY EPIC SEC Emory 02/03/2016 $20,000.00 Practical Intervention Course--Southeast Consortium ------------------------------------------------------------------------ THE ENDOCRINE SOCIETY DMS 2016: 02/07/2016 $235,318.22 Initiating the Conversation: Sharing Perspectives on Advances in T2DM Treatment to Improve Patient- Centered Care ------------------------------------------------------------------------ CONQUER CANCER 2016 ASCO Annual 02/07/2016 $56,000.00 FOUNDATION OF THE Meeting Lung AMERICAN SOCIETY OF Cancer Track CLINICAL ONCOLOGY ------------------------------------------------------------------------ SOCIETY FOR SCAI 2016 02/14/2016 $25,000.00 CARDIOVASCULAR Scientific ANGIOGRAPHY AND Sessions INTERVENTIONS FOUNDATION ------------------------------------------------------------------------ SOCIETY OF HOSPITAL Hospital Medicine 02/14/2016 $15,000.00 MEDICINE 2016 ------------------------------------------------------------------------ AMERICAN HEAD AND NECK American Head and 02/17/2016 $50,000.00 SOCIETY Neck Society 9th International Conference on Head and Neck Cancer ------------------------------------------------------------------------ GLOBAL EDUCATION GROUP Clinical Issues in 02/18/2016 $411,613.00 Type 2 Diabetes: Consensus and Controversies Around Intensifying Noninsulin Therapy. ------------------------------------------------------------------------ NYU POST-GRADUATE Seminar in 03/01/2016 $5,000.00 MEDICAL SCHOOL Advanced Rheumatology ------------------------------------------------------------------------ NEW MEXICO THORACIC 44th Annual New 03/01/2016 $5,000.00 SOCIETY Mexico Lung Disease Symposium--50 Shades of Blue ------------------------------------------------------------------------ MEDSTAR WASHINGTON 14th International 03/01/2016 $10,000.00 HOSPITAL CENTER Congress on Targeted Anticancer Therapies ------------------------------------------------------------------------ FEDERATION OF AMERICAN FASEB Conference 03/01/2016 $6,000.00 SOCIETIES FOR on Genome EXPERIMENTAL BIOLOGY Engineering Cutting-Edge Research and Application ------------------------------------------------------------------------ DIVISION OF MEDICINAL Division of 03/01/2016 $2,500.00 CHEMISTRY Medicinal Chemistry Program 251st ACS National Meeting ------------------------------------------------------------------------ NATIONAL ASSOCIATION OF Personalizing 03/01/2016 $35,000.00 MANAGED CARE Therapy for PHYSICIANS, INC. Improved Patient Outcomes in the Management of Advanced Non Small-Cell Lung Cancer (NSCLC) ------------------------------------------------------------------------ THE AMERICAN THORACIC ATS 2016 03/01/2016 $20,000.00 SOCIETY International Conference--Selec ted Topics in Lung Cancer ------------------------------------------------------------------------ THE ASSOCIATION FOR Building an 03/01/2016 $2,500.00 FRONOTOTEMPORAL Infrastructure to DEGENERATION Support FTLD Therapeutic Development ------------------------------------------------------------------------ WASHINGTON ACADEMY OF 27th Annual 03/01/2016 $1,750.00 PHYSICIAN ASSISTANTS Recertification Review Course and Spring Conference ------------------------------------------------------------------------ ONCOLOGY NURSING 41st Annual 03/01/2016 $35,000.00 SOCIETY Oncology Nursing Society Congress and Pharmacology Highlights regional program ------------------------------------------------------------------------ GORDON RESEARCH Chemical 03/01/2016 $2,500.00 CONFERENCES Approaches for Unraveling Biology ------------------------------------------------------------------------ GORDON RESEARCH Medicinal 03/01/2016 $3,000.00 CONFERENCE Chemistry Gordon Research Conference ------------------------------------------------------------------------ NATIONAL ASSOCIATION OF 2016 Charitable 03/01/2016 $30,000.00 FREE AND CHARITABLE Health Care CLINICS Symposium ------------------------------------------------------------------------ THE HOPE FOUNDATION 2016 SWOG Group 03/01/2016 $10,000.00 Meetings ------------------------------------------------------------------------ HEMATOLOGY/ONCOLOGY 2016 Hematology/ 03/01/2016 $25,000.00 PHARMACY ASSOCIATION Oncology PHarmacy Association ------------------------------------------------------------------------ MEDICAL LEARNING New Developments 03/03/2016 $65,763.00 INSTITUTE INC. in the Treatment of COPD: Updates From San Francisco (150203884) ------------------------------------------------------------------------ AMERICAN 11th Postgraduate 03/03/2016 $10,000.00 NEUROGASTROENTEROLOGY Course on GI AND MOTILITY SOCIETY Motility and Neurogastroentero logy in Clinical Practice ------------------------------------------------------------------------ AMERICAN ACADEMY OF AAPA Conference 03/03/2016 $5,000.00 PHYSICIAN ASSISTANT 2016--Allergy/ Immunology and Pulmonology Track ------------------------------------------------------------------------ GORDON RESEARCH Gordon Research 03/07/2016 $3,000.00 CONFERENCE Conference on Cyclic Nucleotide Phosphodiesterase s: Mechanisms of PDE Nano-Domain Control and Impacts on Disease ------------------------------------------------------------------------ AMERICAN THORACIC ATS 2016 03/07/2016 $70,000.00 SOCIETY International Conference--Selec ted Topics in COPD ------------------------------------------------------------------------ MASSACHUSETTS GENERAL CoNNCT Workshop 03/07/2016 $2,000.00 HOSPTIAL (Collaborative Novel-Novel Cancer Therapies) ------------------------------------------------------------------------ COLLEGIUM 31st Symposium of 03/08/2016 $10,000.00 INTERNATIONALE the Collegium ALLERGOLOGICUM Internationale Allergologicum ------------------------------------------------------------------------ NATIONAL ASSOCIATION OF Improving Outcomes 03/08/2016 $25,000.00 MANAGED CARE in the Management PHYSICIANS and Treatment of Asthma ------------------------------------------------------------------------ NATIONAL ASSOCIATION OF Identifying New 03/08/2016 $25,000.00 MANAGED CARE Strategies to PHYSICIANS Optimize the Management and Treatment of COPD ------------------------------------------------------------------------ NORTHEASTERN SECTION OF NESACS Advances in 03/08/2016 $1,500.00 THE AMERICAN CHEMICAL Chemical Sciences SOCIETY, INC. Symposium ------------------------------------------------------------------------ AMERICAN THORACIC ATS 2016 03/08/2016 $30,000.00 SOCIETY INC. International Conference--Selec ted Topics in Asthma ------------------------------------------------------------------------ YALE UNIVERSITY 4th Annual Yale 03/08/2016 $15,000.00 COPD Symposium ------------------------------------------------------------------------ FLORIDA ALLERGY, ASTHMA Florida Allergy, 03/14/2016 $15,000.00 AND IMMUNOLOGY SOCIETY Asthma and Immunology Society 2016 Annual CME Conference ------------------------------------------------------------------------ UNIVERSITY OF Keep your patients 03/14/2016 $25,000.00 CONNECTICUT ``moving''--An Overview of Treatment Options for Constipation ------------------------------------------------------------------------ UHS PROFESSIONAL 32nd Annual 03/14/2016 $10,000.00 EDUCATIONAL PROGRAMS, Congress of INC. Clinical Rheumatology ------------------------------------------------------------------------ NATIONAL KIDNEY CKD-Related Anemia 03/17/2016 $100,050.00 FOUNDATION and Cardiovascular Risk ------------------------------------------------------------------------ UHS-PROFESSIONAL 1st Annual 03/23/2016 $5,000.00 EDUCATION PROGRAMS Advances in Pain INC. Care ------------------------------------------------------------------------ GORDON RESEARCH Gordon Research 03/23/2016 $1,000.00 CONFERENCE Conference on Cyclic Nucleotide Phosphodiesterase s: Mechanisms of PDE Nano-Domain Control and Impacts on Disease ------------------------------------------------------------------------ OUHSC COLLEGE OF 19th Annual 03/24/2016 $1,500.00 MEDICINE OFFICE OF CPD Primary Care Update ------------------------------------------------------------------------ TENNESSEE ACADEMY OF Spring Fling 2016-- 03/27/2016 $3,000.00 PHYSICIAN ASSISTANTS Asthma and COPD ------------------------------------------------------------------------ AMERICAN THORACIC ATS 2016 03/28/2016 $10,000.00 SOCIETY INC. 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Thrombosis and Vascular Biology Peripheral Vascular Disease 2016 ------------------------------------------------------------------------ AMERICAN UROLOGICAL AUA2016 Highlights 04/11/2016 $25,000.00 ASSOCIATION EDUCATION in Bladder Cancer and RESEARCH INC. ------------------------------------------------------------------------ NATIONAL KIDNEY National Kidney 04/11/2016 $5,000.00 FOUNDATION Foundation s Ninth Annual Mid- Atlantic First Year Renal Fellows Symposium ------------------------------------------------------------------------ THOMAS JEFFERSON 5th Annual 04/11/2016 $3,000.00 UNIVERSITY Palliative Care Spring Symposium ------------------------------------------------------------------------ COLUMBUS NCORP 2016 ASCO REVIEW 04/12/2016 $2,000.00 ------------------------------------------------------------------------ ALZHEIMER'S ASSOCIATION 2016 Alzheimer's 04/12/2016 $45,000.00 Association International Conference ------------------------------------------------------------------------ NATIONAL COMPREHENSIVE 2016-2017 Monthly 04/12/2016 $49,008.06 CANCER NETWORK Oncology Tumor Boards: A Multidisciplinary Approach to Individualized Patient Care ------------------------------------------------------------------------ WASHINGTON UNIVERSITY Advances in Lung 04/13/2016 $3,000.00 Cancer ------------------------------------------------------------------------ TRANSLATIONAL RESEARCH TRIO-US and UCLA 04/14/2016 $3,000.00 IN ONCOLOGY-US, INC. Annual Research Conference ------------------------------------------------------------------------ YALE UNIVERSITY Yale ASCO Review 04/17/2016 $2,000.00 2016 ------------------------------------------------------------------------ SOCIETY FOR SITC 31st Annual 04/17/2016 $300,000.00 IMMUNOTHERAPY OF Meeting CANCER ------------------------------------------------------------------------ SOCIETY FOR 2016 Primer on 04/17/2016 $50,000.00 IMMUNOTHERAPY OF Tumor Immunology CANCER and Cancer Immunotherapy ------------------------------------------------------------------------ INTERNATIONAL IASLC Fellowship/ 04/18/2016 $43,000.00 ASSOCIATION FOR THE Young STUDY OF LUNG CANCER Investigator Award ------------------------------------------------------------------------ AMERICAN SOCIETY FOR ASTRO 2016 58th 04/18/2016 $10,000.00 RADIATION ONCOLOGY Annual Meeting ------------------------------------------------------------------------ NORTHWESTERN UNIVERSITY 18th Annual Lynn 04/18/2016 $10,000.00 Sage Breast Cancer Symposium ------------------------------------------------------------------------ AMERICAN COLLEGE OF GAIN (EnGAiging an 04/19/2016 $500,000.00 CHEST PHYSICIANS Inter- Disciplinary Team for NSCLC Diagnosis, Personalized Assessment, and Treatment) ------------------------------------------------------------------------ AMERICAN ASSOCIATION 11th Biennial 04/21/2016 $10,000.00 FOR CANCER RESEARCH Ovarian Cancer Research Symposium ------------------------------------------------------------------------ METABOLIC ENDOCRINE 14th Annual World 04/21/2016 $75,000.00 EDUCATION FOUNDATION Congress on Insulin Resistance Diabetes and Cardiovascular Disease--WCIRDC ------------------------------------------------------------------------ C-CHANGE Catalyzing Change 04/24/2016 $50,000.00 in Big Data and Value in Cancer Care ------------------------------------------------------------------------ CONQUER CANCER 2016 ASCO Pre- 04/24/2016 $5,000.00 FOUNDATION OF THE Annual Meeting AMERICAN SOCIETY OF Seminar: How to CLINICAL ONCOLOGY Integrate Tumor Immunotherapy into Your Clinical Practice ------------------------------------------------------------------------ UNIVERSITY OF FLORIDA Southern Salt, 04/24/2016 $3,000.00 FOUNDATION INC. 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Roadmap Symposium ------------------------------------------------------------------------ AMERICAN SOCIETY OF ASH Scholar Award 05/25/2016 $50,000.00 HEMATOLOGY ------------------------------------------------------------------------ AMERICAN ASSOCIATION AACR Conference on 05/25/2016 $35,000.00 FOR CANCER RESEARCH Tumor Immunology and Immunotherapy ------------------------------------------------------------------------ SCRIPPS HEALTH 13th Annual 05/26/2016 $2,000.00 Oncology Update ------------------------------------------------------------------------ DANA FARBER CANCER International 06/02/2016 $10,000.00 INSTITUTE Workshop on Waldenstroms macroglobulinemia and symposia on Multiple myeloma (IWWM9) ------------------------------------------------------------------------ FRIENDS OF CANCER 2016 Friends of 06/05/2016 $100,000.00 RESEARCH Cancer Research Programs ------------------------------------------------------------------------ PARTNERS HEALTHCARE Massachusetts 06/08/2016 $4,771.88 SYSTEM, INC. General Hospital Multidisciplinary Breast Rounds ------------------------------------------------------------------------ VIVA PHYSICIANS, INC. VIVA 16: Vascular 06/12/2016 $25,000.00 InterVentional Advances ------------------------------------------------------------------------ UNIVERSITY OF COLORADO Sex Differences 06/16/2016 $35,000.00 DENVER, CENTER FOR Across the WOMEN'S HEALTH HEALTH Lifespan: A Focus RESEARCH on Metabolism ------------------------------------------------------------------------ THE BOARD OF REGENTS OF Immunotherapy: 06/20/2016 $40,000.00 THE UNIVERSITY OF Transformation of NEBRASKA Therapies for Blood Cancer a satellite symposium held in conjunction with the 2016 ASH Annual Meeting ------------------------------------------------------------------------ VIVA PHYSICIANS, INC. The Blockbuster at 06/21/2016 $69,100.00 VIVA 16 ------------------------------------------------------------------------ AMERICAN COLLEGE OF COPD Learning 06/22/2016 $40,000.00 CHEST PHYSICIANS Track ------------------------------------------------------------------------ ENDOCRINE FELLOWS Third Annual 06/23/2016 $278,000.00 FOUNDATION Endocrine Fellows Foundation Research Meeting ------------------------------------------------------------------------ AMERICAN CANCER SOCIETY American Cancer 06/30/2016 $163,500.00 INC. Society Post- Doctoral Research Fellowship Program ------------------------------------------------------------------------ AMERICAN COLLEGE OF Breathing New Air 07/03/2016 $10,000.00 OSTEOPATHIC into the INTERNISTS, INC. Treatment of COPD and Asthma ------------------------------------------------------------------------ UNIVERSITY OF TEXAS 39th Annual San 07/03/2016 $75,000.00 HEALTH SCIENCE CENTER Antonio Breast AT SAN ANTONIO SCHOOL Cancer Symposium OF MEDICINE--OFFICE OF CME ------------------------------------------------------------------------ NATIONAL JEWISH HEALTH Evaluation and 07/04/2016 $94,011.50 Treatment of Severe Asthma: The Role of Biologic and Directed Therapies ------------------------------------------------------------------------ NATIONAL MEDICAL Chronic 07/04/2016 $150,000.00 ASSOCIATION Obstructive Pulmonary Disease Interdisciplinary Diagnostic and Treatment Symposium ------------------------------------------------------------------------ GORDON RESEARCH Gordon Research 07/10/2016 $1,440.00 CONFERENCE Seminar in Microbial Toxins and Pathogenesis ------------------------------------------------------------------------ AMERICAN ACADEMY OF 34th Annual Aspen 07/13/2016 $5,200.00 ALLERGY, ASTHMA AND Allergy IMMUNOLOGY Conference ------------------------------------------------------------------------ GORDON RESEARCH 2016 Protein 07/13/2016 $5,000.00 CONFERENCE Processing Trafficking and Secretion ------------------------------------------------------------------------ SOCIETY FOR New Cancer 07/14/2016 $35,000.00 IMMUNOTHERAPY OF Immunotherapy CANCER Agents in Development ------------------------------------------------------------------------ AMINISTRATORS OF THE 16th Annual SSCI 07/14/2016 $49,939.06 TULANE EDUCATIONAL Nephrology Young FUND Investigators' Forum ------------------------------------------------------------------------ NEW YORK ACADEMY OF Targeting 07/18/2016 $15,000.00 SCIENCES Inflammation and Podocytopathy in Chronic Kidney Disease ------------------------------------------------------------------------ SOCIETY FOR SITC 2016 Workshop 07/19/2016 $150,000.00 IMMUNOTHERAPY OF on Challenges, CANCER Insights, and Future Directions for Mouse and Humanized Models in Cancer Immunology and Immunotherapy ------------------------------------------------------------------------ MASSACHUSETTS GENERAL 31th Annual 07/21/2016 $10,000.00 HOSPITAL Critical Issues In Tumor Microenvironment: Angiogenesis, Metastasis and Immunology ------------------------------------------------------------------------ CARDIOVASCULAR RESEARCH Transcatheter 07/21/2016 $10,000.00 FOUNDATION Cardiovascular Therapeutics (TCT) 2016 ------------------------------------------------------------------------ PEPTIDE THERAPEUTICS 11th Annual 07/26/2016 $15,000.00 FOUNDATION Peptide Therapeutics Symposium ------------------------------------------------------------------------ AMERICAN SOCIETY OF ASN Kidney Week-- 07/27/2016 $20,000.00 NEPHROLOGY CKD Learning Pathway Support ------------------------------------------------------------------------ AMERICAN ASSOCIATION AACR DNA Repair: 07/31/2016 $25,000.00 FOR CANCER RESEARCH Tumor Development and Therapeutic Response ------------------------------------------------------------------------ NATIONAL COMPREHENSIVE NCCN 2016 Congress 08/01/2016 $50,000.00 CANCER NETWORK INC. Series: Immunotherapies in Cancer ------------------------------------------------------------------------ CEDARS SINAI MEDICAL Pancreatic Cancer 08/03/2016 $3,000.00 CENTER Conference ------------------------------------------------------------------------ NATIONAL COMPREHENSIVE NCCN 2016 Congress 08/04/2016 $25,000.00 CANCER NETWORK INC. Series: Utilizing Guidelines to Customize Patient Care in Non-Small Cell Lung Cancer ------------------------------------------------------------------------ AMERICAN COLLEGE OF Managing Severe 08/04/2016 $12,500.00 ALLERGY, ASTHMA AND Asthma in Adults IMMUNOLOGY and Children Workshop ------------------------------------------------------------------------ ILLINOIS ACADEMY OF Tenth Annual 08/07/2016 $54,768.91 FAMILY PHYSICIANS Family Medicine Chief Residents 2016 Summit: Intensifying Diabetes Management ------------------------------------------------------------------------ NATIONAL COMPREHENSIVE Advanced Non-Small 08/10/2016 $100,000.00 CANCER NETWORK, INC. Cell Lung Cancer Patient Management Simulator ------------------------------------------------------------------------ AMERICAN ASSOCIATION OF AACE 2016 Balance 08/11/2016 $233,374.80 CLINICAL of Evidence: ENDOCRINOLOGISTS Considering the Clinical Impact of Newer Antihyperglycemic Agents for the Treatment of Type 2 Diabetes ------------------------------------------------------------------------ HOUSTON METHODIST 4th Annual Houston 08/11/2016 $3,000.00 HOSPITAL Methodist Cancer Symposium ------------------------------------------------------------------------ THE AMERICAN AASLD/EASL HBV 08/14/2016 $3,000.00 ASSOCIATION FOR THE Treatment STUDY OF LIVER Endpoints DISEASES Workshop ------------------------------------------------------------------------ ASTHMA AND ALLERGY Wheezin', Sneezin' 08/15/2016 $5,000.00 FOUNDATION OF AMERICA, and Itchin' in ALASKA CHAPTER Alaska ------------------------------------------------------------------------ DANA-FARBER CANCER Dana-Farber Cancer 08/15/2016 $2,500.00 INSTITUTE INC. Institute's 12 th Annual Postdoctoral and Graduate Student Retreat ------------------------------------------------------------------------ GLOBAL VIRUS NETWORK 3rd Annual Short 08/16/2016 $5,000.00 INC. Course for emerging leaders in Medical Virology of the Global Virus Network ------------------------------------------------------------------------ AMERICAN COLLEGE OF Eastern Pulmonary 08/21/2016 $8,000.00 ALLERGY, ASTHMA AND Conference 2016 IMMUNOLOGY ------------------------------------------------------------------------ CURATORS OF THE 2017 Midwest 08/25/2016 $35,260.00 UNIVERSITY OF MISSOURI Nephrology Fellows Research Day ------------------------------------------------------------------------ GORDON RESEARCH Mammalian DNA 08/25/2016 $2,000.00 CONFERENCES Repair Gordon Research Conference and Seminar ------------------------------------------------------------------------ NATIONAL JEWISH HEALTH The 21st Annual 08/28/2016 $3,000.00 Regional Allied Health Conference: Current Perspectives in Asthma, Allergy and Pulmonary Practice ------------------------------------------------------------------------ LUNGEVITY FOUNDATION LUNGevity 08/28/2016 $25,000.00 Foundation Science and Clinical Research Roundtable, Part II ------------------------------------------------------------------------ REGENTS OF THE 14th Annual 08/29/2016 $49,509.01 UNIVERSITY OF Nephrology Young CALIFORNIA Investigator's Forum ------------------------------------------------------------------------ UNIVERSITY OF MARYLAND 18th Annual 09/01/2016 $5,000.00 BALTIMORE FOUNDATION, International INC. Meeting of the Institute of Human Virology ------------------------------------------------------------------------ INTERNATIONAL IASLC 17th Wolrd 09/04/2016 $82,500.00 ASSOCIATION FOR THE Conference on STUDY OF LUNG CANCER Lung Cancer-- International Mentorship Awards ------------------------------------------------------------------------ USF HEALTH PROFESSIONS Update in Allergy 09/07/2016 $3,000.00 CONFERENCING and Immunology CORPORATION 2016 Symposium and Rhinolarngoscopy Hands-On Workshop ------------------------------------------------------------------------ UNIVERSITY OF NEW Update and Review 09/07/2016 $2,500.00 MEXICO of Internal Medicine ------------------------------------------------------------------------ PRESIDENT AND FELLOWS GI Motility and 09/08/2016 $1,500.00 OF HARVARD COLLEGE Functional GI Disease: Evidence vs. Consensus ------------------------------------------------------------------------ AMERICAN COLLEGE OF ACT's 37th Annual 09/08/2016 $5,000.00 TOXICOLOGY Meeting ------------------------------------------------------------------------ PERSONALIZED MEDICINE 12th Annual 09/11/2016 $5,000.00 COALITION Personalized Medicine Conference ------------------------------------------------------------------------ UNIVERSITY OF SOUTHERN 1st Annual 09/13/2016 $5,000.00 CALIFORNIA Southern California Kidney Symposium: ``Slowing the Progression of Kidney Disease: From Bench to Bedside'' ------------------------------------------------------------------------ NATIONAL ASSOCIATION OF Optimizing 09/21/2016 $35,000.00 MANAGED CARE Outcomes in PHYSICIANS, INC. Advanced Non- Small Cell Lung Cancer (NSCLC): Integrating Novel Personalized Therapy into the Treatment Paradigm ------------------------------------------------------------------------ ANNENBERG CENTER FOR 2016 JADPRO Live 09/22/2016 $100,000.00 HEALTH SCIENCES AT at APSHO EISENHOWER ------------------------------------------------------------------------ PARTNERS HEALTHCARE Massachusetts 09/22/2016 $5,000.00 SYSTEM, INC. General Hospital Multidisciplinary Breast Rounds 2016-2017 ------------------------------------------------------------------------ UNIVERSITY OF FLORIDA Vascular Biology 09/22/2016 $7,800.00 Working Group Global Chapter Meeting ------------------------------------------------------------------------ JOHNS HOPKINS Allergy Grand 09/25/2016 $2,846.55 UNIVERSITY Rounds ------------------------------------------------------------------------ AMERICAN ASSOCIATION AACR-AstraZeneca 09/25/2016 $126,500.00 FOR CANCER RESEARCH Fellowship in Ovarian Cancer Research ------------------------------------------------------------------------ PHARMACY QUALITY PQA Leadership 09/25/2016 $5,000.00 ALLIANCE (PQA, INC.) Summit 2016 The I's Have It! Insights into Innovations, Integration and Implementation Strategies for Medication Use Measurement ------------------------------------------------------------------------ NATIONAL COMPREHENSIVE NCCN 2017 Congress 09/27/2016 $25,000.00 CANCER NETWORK INC. Series : Breast Cancer with Updates from the 2016 San Antonio Breast Cancer Symposium ------------------------------------------------------------------------ THE SCRIPPS RESEARCH 28th Annual 09/27/2016 $1,500.00 INSTITUTE Frontiers in Chemistry Symposium ------------------------------------------------------------------------ THE GOG FOUNDATION INC. 7th Semi Annual 09/28/2016 $20,000.00 Meeting of NRG Oncology (formerly; GOG, NSABP, RTOG) ------------------------------------------------------------------------ INTERNATIONAL Global CME program 09/28/2016 $25,000.00 FEDERATION OF HEAD AND of IFHNOS NECK ONCOLOGIC SOCIETIES ------------------------------------------------------------------------ PARKER INSTITUTE FOR PICI Cancer 09/28/2016 $30,000.00 CANCER IMMUNOTHERAPY Immunotherapy Workshops ------------------------------------------------------------------------ SOCIEDAD PUERTORRIQUE A Endocrinology Now 10/02/2016 $5,000.00 DE ENDOCRINOLOG A Y and Then SPEDs DIABETOLOGIA 40th Anniversary ------------------------------------------------------------------------ UNIVERSITY OF TEXAS Cancer Genetics: 10/03/2016 $5,000.00 SOUTHWESTERN MEDICAL Finding Meaning CENTER in Tumor and Germline Genomes ------------------------------------------------------------------------ NATIONAL KIDNEY 12th Annual 10/03/2016 $50,000.00 FOUNDATION National Young Investigator's Forum ------------------------------------------------------------------------ THE UNIVERSITY OF TEXAS The Fourth 10/05/2016 $5,000.00 MD ANDERSON CANCER International CENTER Conference on Cancer and the Heart ------------------------------------------------------------------------ AMERICAN ASSOCIATION AACR Translational 10/05/2016 $25,000.00 FOR CANCER RESEARCH Control of Cancer: A New Frontier in Cancer Biology and Therapy ------------------------------------------------------------------------ METABOLIC ENDOCRINE 14th Annual World 10/05/2016 $25,000.00 EDUCATION FOUNDATION Congress on Insulin Resistance Diabetes and Cardiovascular Disease (WCIRDC) ------------------------------------------------------------------------ CEDARS-SINAI MEDICAL 5th Annual New 10/06/2016 $5,000.00 CENTER Therapeutics in Oncology: The Road to Personalized Medicine ------------------------------------------------------------------------ NATIONAL COMPREHENSIVE Behind the 10/06/2016 $25,000.00 CANCER NETWORK INC. Guidelines: Insights into the Standard of Care in Oncology 2017 ------------------------------------------------------------------------ NATIONAL KIDNEY Chronic Kidney 10/06/2016 $139,980.00 FOUNDATION INC. Disease and Cardiovascular Disease: Best Practices to Improve Outcomes ------------------------------------------------------------------------ ECOG RESEARCH AND Fall 2016 ECOG- 10/09/2016 $5,000.00 EDUCATION FOUNDATION, ACRIN Group INC. Meeting ------------------------------------------------------------------------ INTERNATIONAL IASLC 17th World 10/09/2016 $170,000.00 ASSOCIATION FOR THE Conference on STUDY OF LUNG CANCER Lung Cancer ------------------------------------------------------------------------ CONQUER CANCER 2017 Conquer 10/10/2016 $40,000.00 FOUNDATION OF THE Cancer Foundation AMERICAN SOCIETY OF of ASCO Merit CLINICAL ONCOLOGY Awards ------------------------------------------------------------------------ PARTERS HEALTHCARE Massachusetts 10/10/2016 $5,000.00 SYSTEM, INC. General Hospital Cancer Center Grand Rounds ------------------------------------------------------------------------ UNIVERSIDAD CENTRAL DEL Redefining Cancer 10/11/2016 $5,000.00 CARIBE, INC. Treatment Paradigms in Non- Small Cell Lung Cancer ------------------------------------------------------------------------ RUSH UNIVERSITY MEDICAL Expert Insights 10/18/2016 $5,000.00 CENTER and Key Nursing Considerations: Treating and Caring for Patients with Lung Cancer ------------------------------------------------------------------------ GLOBAL EDUCATION GROUP GOLD COPD: 10/18/2016 $75,000.00 Continuum of Care ------------------------------------------------------------------------ NATIONAL COMPREHENSIVE NCCN 22nd Annual 10/18/2016 $100,000.00 CANCER NETWORK Conference: Improving the Quality, Effectiveness, and Efficiency of Cancer CareTM ------------------------------------------------------------------------ SOCIETY FOR 2016 Chabner 10/19/2016 $10,000.00 TRANSLATIONAL ONCOLOGY Colloquium: Answering the Big Questions in Cancer Research ------------------------------------------------------------------------ HEMATOLOGY ONCOLOGY 2017 Hematology 10/26/2016 $27,500.00 PHARMACY ASSOCITATION Oncology Pharmacy Association q ------------------------------------------------------------------------ INTERNATIONAL 10th Biennial 10/27/2016 $10,000.00 EOSINOPHIL SOCIETY, Symposium INC. ------------------------------------------------------------------------ CONQUER CANCER 2017 ASCO-SITC 11/03/2016 $13,750.00 FOUNDATION OF THE Clinical Immuno- AMERICAN SOCIETY OF Oncology CLINICAL ONCOLOGY Symposium Proceedings ------------------------------------------------------------------------ MEDSTAR GEORGETOWN LUNG CANCER 2016: 11/03/2016 $5,000.00 UNIVERSITY HOSPITAL Progress and Future Directions ------------------------------------------------------------------------ AMERICAN ASSOCIATION OF 18th Annual 11/03/2016 $15,000.00 CLINICAL Intensive Course ENDOCRINOLOGISTS INC. on Diabetes, Endocrinology, and Metabolic Diseases ------------------------------------------------------------------------ GORDON RESEARCH Mammalian DNA 11/03/2016 $3,000.00 CONFERENCES Repair Gordon Research Conference and Seminar ------------------------------------------------------------------------ AMERICAN ASSOCIATION AACR-AstraZeneca 11/08/2016 $73,238.00 FOR CANCER RESEARCH Fellowships in Lung Cancer Research ------------------------------------------------------------------------ PENN STATE UNIVERSITY Cases from the 11/08/2016 $30,000.00 Community: Investigator Perspectives on Emerging Research and Patients with Advanced Prostate Cancer: A 2017 GU Cancers Symposium ISS ------------------------------------------------------------------------ KEYSTONE SYMPOSIA ON Genomic 11/08/2016 $5,000.00 MOLECULAR AND CELLULAR Instability and BIOLOGY DNA Repair ------------------------------------------------------------------------ RENAL PHYISICIANS RPA 2017 Annual 11/10/2016 $25,000.00 ASSOCIATION Meeting ------------------------------------------------------------------------ AMERICAN ASSOCIATION AACR-AstraZeneca 11/13/2016 $253,000.00 FOR CANCER RESEARCH Fellowships in Immuno-oncology Research ------------------------------------------------------------------------ WINGATE UNIVERSITY AmCare Pharmacy 11/21/2016 $500.00 SCHOOL OF PHARMACY Forum of North Carolina ------------------------------------------------------------------------ SOCIETY FOR NEURO- 21st Annual 11/28/2016 $26,000.00 ONCOLOGY Meeting of the Society for Neuro- Oncology ------------------------------------------------------------------------ LYMPHOMA RESEARCH Lymphoma Research 12/01/2016 $105,000.00 FOUNDATION Foundation Postdoctoral Fellowship Grant Program ------------------------------------------------------------------------ UNIVERSITY OF NEBRASKA PARP Inhibition in 12/01/2016 $45,000.00 MEDICAL CENTER Ovarian Cancer: Integrating Basic Science, Clinical Data, and the Patient Voice to Enhance Care ------------------------------------------------------------------------ KEYSTONE SYMPOSIA 2017 Keystone 12/01/2016 $25,000.00 Symposia Directors' Fund ------------------------------------------------------------------------ BOSTON UNIVERSITY Are You Asking the 12/04/2016 $149,275.00 SCHOOL OF MEDICINE-- Question? OFFICE OF CME Strategies for Engaging the Patient in the Diagnosis and Management of Opioid-Induced Constipation ------------------------------------------------------------------------ GLOBAL EDUCATION GROUP Comprehensive Pain 12/04/2016 $324,107.00 Management in Palliative Care: Relieving the Burden of Opioid- Induced Constipation ------------------------------------------------------------------------ CONQUER CANCER 2017 Conquer 12/04/2016 $500,000.00 FOUNDATION OF THE Cancer Foundation AMERICAN SOCIETY OF of the American CLINICAL ONCOLOGY Society of Clinical Oncology Mission Endowment ------------------------------------------------------------------------ AMERICAN ASSOCIATION AACR Annual 12/04/2016 $150,000.00 FOR CANCER RESEARCH Meeting- 2017 ------------------------------------------------------------------------ SOCIETY OF GYNECOLOGIC Clinical 12/04/2016 $50,000.00 ONCOLOGY Management of New Biologics and Immunotherapies in Gynecologic Oncology ------------------------------------------------------------------------ SOCIETY OF GYNECOLOGIC Genetic Counseling 12/04/2016 $210,575.00 ONCOLOGY in Gynecologic Oncology: What Advanced Practitioners Need to Know ------------------------------------------------------------------------ JOHNS HOPKINS DIVISION Mid-Atlantic 12/04/2016 $50,000.00 OF NEPHORLOGY Nephrology Young Investigators Forum ------------------------------------------------------------------------ INTERNATIONAL EGFR Atlas 12/04/2016 $380,000.00 ASSOCIATION FOR THE STUDY OF LUNG CANCER ------------------------------------------------------------------------ INTERNATIONAL 2017 IASLC WCLC 12/04/2016 $150,000.00 ASSOCIATION FOR THE Association- STUDY OF LUNG CANCER Satellite Fee ------------------------------------------------------------------------ FRIENDS OF CANCER 2017 Friends of 12/04/2016 $100,000.00 RESERACH Cancer Research Programs ------------------------------------------------------------------------ THE UNIVERSITY OF TEXAS 2017 Oncologic 12/06/2016 $5,000.00 MD ANDERSON CANCER Emergency CENTER Medicine Conference ------------------------------------------------------------------------ CONQUER CANCER 2017 Genitourinary 12/08/2016 $50,000.00 FOUNDATION OF THE (GU) Cancers AMERICAN SOCIETY OF Symposium: CLINICAL ONCOLOGY Translating Research to Value- Based and Patient- Centric Care ------------------------------------------------------------------------ ALZHEIMER'S ASSOCIATION 2017 Alzheimer's 12/08/2016 $50,000.00 Association Research Roundtable ------------------------------------------------------------------------ ALZHEIMER'S ASSOCIATION 2017 Alzheimer's 12/08/2016 $45,000.00 Association International Conference ------------------------------------------------------------------------ CANCER RESEARCH Cancer Research 12/11/2016 $50,000.00 INSTITUTE Institute's Irvington Postdoctoral Fellowship Program ------------------------------------------------------------------------ CONQUER CANCER 2017 ASCO-SITC 12/11/2016 $60,000.00 FOUNDATION OF THE Clinical Immuno- AMERICAN SOCIETY OF Oncology CLINICAL ONCOLOGY Symposium ------------------------------------------------------------------------ NATIONAL COMPREHENSIVE NCCN 11th Annual 12/12/2016 $15,000.00 CANCER NETWORK, INC. Congress: Hematologic MalignanciesTM ------------------------------------------------------------------------ INTERNATIONAL SOCIETY ISN World Congress 12/12/2016 $130,000.00 OF NEPHROLOGY of Nephrology 2017--WCN 2017 ------------------------------------------------------------------------ AMERICAN ASSOCIATION OF AACE 26th Annual 12/12/2016 $50,000.00 CLINICAL Scientific & ENDOCRINOLOGISTS Clinical Congress--Diabete s Session ------------------------------------------------------------------------ NATIONAL KIDNEY National Kidney 12/12/2016 $5,000.00 FOUNDATION INC. Foundation s Tenth Annual Mid- Atlantic First Year Renal Fellows Symposium ------------------------------------------------------------------------ THE ENDOCRINE SOCIETY Diabetes Masters 12/13/2016 $50,000.00 Series 2017: Negotiating the Therapeutic Terrain: Steps to Identifying Individualized Treatment Approaches for Patients With T2DM ------------------------------------------------------------------------ REGENTS OF THE Making the 12/14/2016 $50,000.00 UNIVERSITY OF Connection CALIFORNIA between Patients and Providers: A Modern Approach to the Treatment of Type 1 and Type 2 Diabetes ------------------------------------------------------------------------ THE NEW YORK ACADEMY OF Cancer 12/14/2016 $20,000.00 SCIENCES Immunotherapy: Frontiers in Cancer Immunotherapy and Quantitative Approaches in Immuno-Oncology ------------------------------------------------------------------------ REGENTS OF THE 44th Annual Family 12/19/2016 $2,792.00 UNIVERSITY OF Medicine CALIFORNIA LOS ANGELES Reffresher Course" ------------------------------------------------------------------------ RUTGERS, THE STATE Rutgers 12/19/2016 $61,728.00 UNIVERSITY OF NEW Pharmaceutical JERSEY Industry Fellowship Program ------------------------------------------------------------------------ CONQUER CANCER 2017 Conquer 12/21/2016 $192,000.00 FOUNDATION OF THE Cancer Foundation AMERICAN SOCIETY OF of ASCO Young CLINICAL ONCOLOGY Investigator Award (YIA) ------------------------------------------------------------------------ NATIONAL COMPREHENSIVE NCCN 2017 Oncology 12/21/2016 $35,000.00 CANCER NETWORK, INC. Fellows Program: New Horizons in Quality Cancer Care at the NCCN 22nd Annual Conference ------------------------------------------------------------------------ METABOLIC ENDOCRINE 1st Annual Heart 12/21/2016 $100,000.00 EDUCATION FOUNDATION in Diabetes ------------------------------------------------------------------------ INTERNATIONAL IASLC 17th World 12/21/2016 $92,500.00 ASSOCIATION FOR THE Conference on STUDY OF LUNG CANCER Lung Cancer ------------------------------------------------------------------------ PRIMARY CARE EDUCATION 11th Annual Chief 12/21/2016 $50,000.00 CONSORTIUM Residents Summit on Intensifying Diabetes Management ------------------------------------------------------------------------ AMERICAN NEPHROLOGY ANNA 2017 National 12/21/2016 $20,000.00 NURSES ASSOCIATION Symposium ------------------------------------------------------------------------ NATIONAL ASSOCIATION OF 2017 Charitable 12/21/2016 $30,000.00 FREE AND CHARITABLE Health Care CLINICS Symposium ------------------------------------------------------------------------ AMERICAN SOCIETY OF ASN Kidney Week 12/21/2016 $37,500.00 NEPHROLOGY Educational Session Support ------------------------------------------------------------------------ AMERICAN SOCIETY OF ASN Kidney Week 12/21/2016 $15,000.00 NEPHROLOGY Early Program Support ------------------------------------------------------------------------ AMERICAN SOCIETY OF ASN Select 12/21/2016 $20,000.00 NEPHROLOGY Streamed Session Support ------------------------------------------------------------------------ AMERICAN UROLOGICAL Emerging 12/27/2016 $100,000.00 ASSOCIATION EDUCATION Immunotherapeutic AND RESEARCH INC. Agents for the Treatment of Bladder Cancer ------------------------------------------------------------------------ AMERICAN SOCIETY OF 2016 American 01/04/2017 $150,000.00 HEMATOLOGY Society of Hematology Annual Meeting ------------------------------------------------------------------------ RUTGERS, THE STATE Severe Asthma: 01/04/2017 $225,000.00 UNIVERSITY OF NEW Clinical JERSEY Phenotypes and the Emerging Age of Personalized Therapy ------------------------------------------------------------------------ TRUSTEES OF BOSTON A Better Life for 01/05/2017 $100,000.00 UNIVERSITY Your Severe Asthma Patients: Targeted Therapies for Fewer Exacerbations ------------------------------------------------------------------------ NATIONAL JEWISH HEALTH Personalized 01/06/2017 $345,500.00 Medicine in Severe Asthma: Applying Emerging Data and Treatments to Everyday Clinical Practice ------------------------------------------------------------------------ PARKER INSTITUTE FOR Streamlining 01/18/2017 $60,000.00 CANCER IMMUNOTHERAPY Toxicity Management Guidelines ------------------------------------------------------------------------ FLORIDA ALLERGY, ASTHMA FAAIS 2017 Annual 01/25/2017 $20,000.00 AND IMMUNOLOGY SOCIETY CME Conference ------------------------------------------------------------------------ NYU POST-GRADUATE Asthma, Airways 01/26/2017 $20,000.00 MEDICAL SCHOOL and Environment ------------------------------------------------------------------------ NATIONAL ASSOCIATION OF Preventing Acute 01/29/2017 $15,000.00 MANAGED CARE Exacerbations PHYSICIANS, INC. though Novel Insights in Treatment Strategies for COPD ------------------------------------------------------------------------ NATIONAL JEWISH HEALTH 39th Annual 01/29/2017 $20,000.00 National Jewish Health Pulmonary and Allergy Update ------------------------------------------------------------------------ INTERNATIONAL Best of World 01/29/2017 $20,000.00 ASSOCIATION FOR THE Conference on STUDY OF LUNG CANCER Lung Cancer ------------------------------------------------------------------------ YALE UNIVERSITY Severe Asthma 02/01/2017 $16,300.00 2016: A Personalized Approach To Treatment ------------------------------------------------------------------------ AMERICAN SOCIETY FOR 2017 02/01/2017 $50,000.00 RADIATION ONCOLOGY Multidisciplinary Thoracic Cancers Symposium ------------------------------------------------------------------------ NATIONAL MEDICAL Implementing the 02/01/2017 $75,000.00 ASSOCCIATION New GOLD Guidelines: Interdisciplinary Management of Chronic Obstructive Pulmonary Disease as a Chronic Disease ------------------------------------------------------------------------ CARDIOVASCULAR Cardiovascular 02/01/2017 $25,000.00 INNOVATIONS FOUNDATION Innovations 2017 ------------------------------------------------------------------------ AMERICAN THORACIC ATS 2017 02/01/2017 $70,000.00 SOCIETY INC. International Conference--Selec ted Topics in COPD ------------------------------------------------------------------------ CARDIOVASCULAR RESEARCH 23rd Annual 02/01/2017 $10,000.00 FOUNDATION Interventional Cardiology Fellows Course ------------------------------------------------------------------------ NATIONAL JEWISH HEALTH 13th Annual 02/01/2017 $283,830.79 Respiratory Disease Young Investigators Forum ------------------------------------------------------------------------ WASHINGTON HOSPITAL Cardiovascular 02/02/2017 $30,000.00 CENTER CORPORATION Research Technologies ------------------------------------------------------------------------ CONNECTICUT PHARMACISTS Breathe Easy: An 02/02/2017 $2,000.00 ASSOCIATION Overview of Inhalers for the Management of Asthma and COPD ------------------------------------------------------------------------ AMERICAN ACADEMY OF AAPA 2017--Allergy/ 02/06/2017 $7,500.00 PHYSICIAN ASSISTANTS, Immunology and INC. 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JOSEPH'S REGIONAL Acute Coronary 02/15/2017 $4,200.00 MEDICAL CENTER Syndrome ------------------------------------------------------------------------ AMERICAN CHEMICAL Division of 02/16/2017 $3,000.00 SOCIETY DIVISION OF Medicinal MEDICINAL CHEMISTRY Chemistry Program 253rd ACS National Meeting ------------------------------------------------------------------------ SOCIETY FOR 2017 Advances in 02/16/2017 $500,000.00 IMMUNOTHERAPY OF Cancer CANCER Immunotherapy Series ------------------------------------------------------------------------ UNIVERSITY OF FLORIDA Vascular Biology 02/16/2017 $5,000.00 Working Group US Chapter Meeting ------------------------------------------------------------------------ CALIFORNIA ACADEMY OF Addressing the 02/16/2017 $3,000.00 PHYSICIAN ASSISTANTS Needs of the ACS Patient ------------------------------------------------------------------------ CARDIOVASCULAR RESEARCH DAPT Dilemmas: A 02/19/2017 $10,000.00 FOUNDATION Case-based Roundtable Tutorial ------------------------------------------------------------------------ INDIANA ACADEMY OF Managing Severe 02/19/2017 $3,921.00 FAMILY PHYSICIANS Asthma in the Family Physician's Office ------------------------------------------------------------------------ ANNENBERG CENTER FOR The Emerging Role 02/19/2017 $188,600.00 HEALTH SCIENCES AT of Molecular EISENHOWER Testing in an Era of Precision Medicine--NSCLC ------------------------------------------------------------------------ ANNENBERG CENTER FOR The Emerging Role 02/19/2017 $188,600.00 HEALTH SCIENCES AT of Molecular EISENHOWER Testing in an Era of Precision Medicine--Ovarian Cancer ------------------------------------------------------------------------ SCRIPPS HEALTH Scripps 37th 02/20/2017 $5,000.00 Annual Conference: Clinical Hematology and Oncology 2017 ------------------------------------------------------------------------ AMERICAN COLLEGE OF The Great K Debate 02/21/2017 $100,000.00 CARDIOLOGY FOUNDATION Continues: Updates and Controversies in Heart Failure Management ------------------------------------------------------------------------ GORDON RESEARCH 2017 Gordon 02/22/2017 $2,500.00 CONFERENCES Conference on Medicinal Chemistry ------------------------------------------------------------------------ INTERNATIONAL 17th Annual 02/22/2017 $33,000.00 ASSOCIATION FOR THE Targeted STUDY OF LUNG CANCER Therapies of lung Cancer Meeting ------------------------------------------------------------------------ AMERICAN ASSOCIATION AACR-AHNS Head and 02/22/2017 $25,000.00 FOR CANCER RESEARCH Neck Cancer Conference: ------------------------------------------------------------------------ ASTHMA AND ALLERGY Wheezin', Sneezin' 02/22/2017 $5,000.00 FOUNDATION OF AMERICA, and Itchin' in ALASKA CHAPTER Alaska ------------------------------------------------------------------------ FASEB SCIENCE RESEARCH FASEB Autoimmunity 02/22/2017 $5,000.00 CONFERENCES ------------------------------------------------------------------------ FEDERATION OF CLINICAL Federation of 02/23/2017 $15,000.00 IMMUNOLOGY SOCIETIES Clinical INC. Immunology Societies Annual Meeting ------------------------------------------------------------------------ THE BOARD OF REGENTS OF Biennial 03/02/2017 $50,000.00 THE UNIVERSITY OF International NEBRASKA Workshop on Chronic Lymphocytic Leukemia (XVII iwCLL 2017) ------------------------------------------------------------------------ NATIONAL KIDNEY Change in 03/02/2017 $50,000.00 FOUNDATION, INC. Albuminuria and GFR as End Points for Clinical Trials in Early Stages of Chronic Kidney Disease: A Scientific Workshop Sponsored by the National Kidney Foundation, European Medicines Agency and the US Food and Drug Administration ------------------------------------------------------------------------ AMERICAN RESPIRATORY 56th RESPIRATORY 03/05/2017 $18,000.00 CARE FOUNDATION CARE Journal Conference Respiratory Medications for COPD and Adult Asthma: Pharmacologic Actions to Clinical Applications ------------------------------------------------------------------------ AMERICAN COLLEGE OF ACAAI member 03/05/2017 $40,000.00 ALLERGY, ASTHMA AND publication--Alle IMMUNOLOGY rgyWatch ------------------------------------------------------------------------ GORDON RESEARCH The Enduring 03/05/2017 $2,500.00 CONFERENCE Potential of Heterocycles as Synthetic Targets, Cellular Probes, and Drug Candidates ------------------------------------------------------------------------ THE REGENTS OF THE 35th Carl M. 03/06/2017 $10,000.00 UNIVERSITY OF Pearson Memorial CALIFORNIA Symposium Frontiers of Rheumatology ------------------------------------------------------------------------ GORDON RESEARCH Staphylococcal 03/06/2017 $5,000.00 CONFERENCES--STAPHYLOC Gordon Research OCCAL DISEASES Conference ------------------------------------------------------------------------ COLD SPRING HARBOR Cell Death 03/07/2017 $2,500.00 LABORATORY ------------------------------------------------------------------------ CEDARS-SINAI MEDICAL Lupus: What's 03/08/2017 $334,625.00 CENTER Next? Examining Mechanisms, Monitoring, and Medication Updates ------------------------------------------------------------------------ AMERICAN THORACIC ATS 2017 Fellows 03/09/2017 $20,000.00 SOCIETY Track Symposium ------------------------------------------------------------------------ BOSTON UNIVERSITY EFFECTIVE ASTHMA 03/11/2017 $100,000.00 SCHOOL OF MEDICINE, MANAGEMENT IN CME PRIMARY CARE: Severity Assessment, Guidelines, and New Therapy Options ------------------------------------------------------------------------ PENNSYLVANIA STATE Innovations in 03/12/2017 $2,500.00 UNIVERSITY Allergy, Asthma and Immunology Management ------------------------------------------------------------------------ INTERNATIONAL IASLC SCLC 03/14/2017 $25,000.00 ASSOCIATION FOR THE workshop STUDY OF LUNG CANCER (IASLC) ------------------------------------------------------------------------ TRUSTEES OF BOSTON A Better Life for 03/14/2017 $321,485.44 UNIVERSITY Your Severe Asthma Patients: Targeted Therapies for Fewer Exacerbations ------------------------------------------------------------------------ REGENTS OF THE Clostpath 10 03/16/2017 $5,000.00 UNIVERSITY OF MICHIGAN Support ------------------------------------------------------------------------ AMERICAN COLLEGE OF Asthma Fellows 03/20/2017 $5,000.00 CHEST PHYSICIANS Conference ------------------------------------------------------------------------ AMERICAN COLLEGE OF Multidisciplinary 03/20/2017 $24,354.00 CHEST PHYSICIANS Management Of Severe Asthma: It Takes A Village ------------------------------------------------------------------------ AMERICAN COLLEGE OF Asthma Learning 03/21/2017 $79,573.00 CHEST PHYSICIANS Track--CHEST 2017 ------------------------------------------------------------------------ AMERICAN COLLEGE OF COPD Learning 03/22/2017 $73,765.00 CHEST PHYSICIANS Track ------------------------------------------------------------------------ THOMAS JEFFERSON 10th Annual Young 03/26/2017 $11,000.00 UNIVERSITY Investigators Forum ------------------------------------------------------------------------ FLORIDA ACADEMY OF Diagnoses and 03/27/2017 $8,000.00 PHYSICIAN ASSISTANTS treatment for INC. 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Medicine Update ------------------------------------------------------------------------ AMERICAN COLLEGE OF 28th Annual 03/29/2017 $5,000.00 CARDIOLOGY PUERTO RICO Meeting of the CHAPTER ACC Puerto Rico Chapter ------------------------------------------------------------------------ HOWARD UNIVERSITY The Kenneth Austin 03/30/2017 $2,500.00 12th Annual Rheumatology Symposium at Howard University Hospital ------------------------------------------------------------------------ AMERICAN RADIUM SOCIETY 99th Annual 04/02/2017 $10,000.00 Meeting of the American Radium Society ------------------------------------------------------------------------ TENNESSEE ACADEMY OF Spring Fling 2017: 04/03/2017 $2,000.00 PHYSICIAN ASSISTANTS Optimizing Outcomes in Patients with Opioid Induced Constipation ------------------------------------------------------------------------ NATIONAL ASSOCIATION OF Navigating a 04/04/2017 $35,000.00 MANAGED CARE Complex Treatment PHYSICIANS, INC. Landscape in Advanced Non- Small Cell Lung Cancer (NSCLC): Individualizing Therapy for Improved Patient Outcomes ------------------------------------------------------------------------ MEDICAL LEARNING Improving the 04/06/2017 $149,000.00 INSTITUTE INC. Physical and Mental Well-Being of Patients With COPD: Integrating Pharmacotherapy With Pulmonary Rehabilitation and Self- Management ------------------------------------------------------------------------ AMERICAN ASSOCIATION OF UPDATES ABOUND! 04/06/2017 $374,606.00 CLINICAL Latest and ENDOCRINOLOGISTS INC. Greatest in Practical Application of Cardiovascular Outcomes for Diabetes Drugs ------------------------------------------------------------------------ GLOBAL EDUCATION GROUP Overcoming 04/06/2017 $289,267.50 Challenges in Cancer Pain Management: Engaging With Patients About Opioid-Induced Constipation ------------------------------------------------------------------------ AMERICAN ASSOCIATION OF AAPS Sustaining 04/09/2017 $50,000.00 PHARMACEUTICAL Sponsorship SCIENTISTS ------------------------------------------------------------------------ THE UNIVERSITY OF 14th International 04/10/2017 $10,000.00 CHICAGO CENTER FOR Ultmann Chicago CONTINUING MEDICAL Lymphoma EDUCATION Symposium ------------------------------------------------------------------------ AMERICAN ASSOCIATION AACR Hematologic 04/10/2017 $25,000.00 FOR CANCER RESEARCH Malignancies: ------------------------------------------------------------------------ THE HOPE FOUNDATION 2017 SWOG Group 04/11/2017 $10,000.00 Meetings ------------------------------------------------------------------------ PREVENTIVE 2017 PCNA FAll 04/11/2017 $25,000.00 CARDIOVASCULAR NURSES Regional ASSOCIATION Education Programs: Cardiometabolics: Focus on New Medications and Risk Reduction Benefits and Protection ------------------------------------------------------------------------ EMORY UNIVERSITY SCHOOL Updates in the 04/12/2017 $5,000.00 OF MEDICINE Management of Head and Neck Cancer ------------------------------------------------------------------------ NATIONAL COMPREHENSIVE NCCN 2017 Congress 04/16/2017 $50,000.00 CANCER NETWORK INC. Series : Lung Cancer ------------------------------------------------------------------------ ONCOLOGY NURSING 42nd Annual ONS 04/16/2017 $50,000.00 SOCIETY Congress and Oncology Updates Regional Meetings ------------------------------------------------------------------------ SWEDISH MEDICAL CENTER Annual Oncology 04/16/2017 $5,000.00 FOUNDATION Symposium: Innovations in Gynecologic Cancer Care-- Prevention to Survivorship ------------------------------------------------------------------------ ANNENBERG CENTER FOR Master Class for 04/18/2017 $10,000.00 HEALTH SCIENCES AT Oncologists--Brea EISENHOWER st Cancer Track ------------------------------------------------------------------------ ANNENBERG CENTER FOR Master Class for 04/18/2017 $10,000.00 HEALTH SCIENCES AT Oncologist--Genit EISENHOWER ourinary Cancers Track ------------------------------------------------------------------------ ANNENBERG CENTER FOR Oral Oncolytics 04/18/2017 $50,000.00 HEALTH SCIENCES AT Adherence EISENHOWER Resource Center: An Educational Platform for Advanced Practitioners in Oncology ------------------------------------------------------------------------ BLADDER CANCER ADVOCACY 2017 Bladder 04/18/2017 $35,000.00 NETWORK Cancer Think Tank ------------------------------------------------------------------------ SOCIETY FOR SCAI 2017 04/23/2017 $50,000.00 CARDIOVASCULAR Scientific ANGIOGRAPHY AND Sessions INTERVENTIONS ------------------------------------------------------------------------ TRUSTEES OF THE BRCA1, BRCA2 and 04/23/2017 $20,000.00 UNIVERSITY OF Beyond: An Update PENNSYLVANIA on Hereditary Cancer ------------------------------------------------------------------------ CANCER MOLECULAR Molecular 04/24/2017 $2,000.00 THERAPEUTICS RESEARCH Therapeutics of ASSOCIATION Cancer Research Conference 2017 ------------------------------------------------------------------------ YALE UNIVERSITY 2017 Lung SPORE 04/24/2017 $30,000.00 Workshop ------------------------------------------------------------------------ ECOG RESEARCH AND ECOG-ACRIN Spring 04/24/2017 $5,000.00 EDUCATION FOUNDATION, 2017 Group INC. 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FRANCIS HOSPITAL Contemporary 05/18/2017 $3,300.00 Dilemmas in Anti Platelet Therapy ------------------------------------------------------------------------ MEMORIAL SLOAN 2017 MSK Cardio- 05/18/2017 $5,000.00 KETTERING CANCER Oncology CENTER Symposium: Cardiovascular Health and Disease During and After Cancer Therapy--A Case Based Curriculum ------------------------------------------------------------------------ GORDON RESEARCH Gordon Research 05/18/2017 $8,000.00 CONFERENCE Seminar and Conference on Lung Development, Injury and Repair ------------------------------------------------------------------------ GORDON RESEARCH Next Generation 05/18/2017 $2,000.00 CONFERENCES Computer-Aided Medicine Design: Going Beyond Traditional Targets, Pathways, Modalities, Agents and Techniques ------------------------------------------------------------------------ REGENTS OF THE 13th Annual 05/19/2017 $5,000.00 UNIVERSITY OF Biomarkers in CALIFORNIA Heart Failure and Acute Coronary Syndromes: Diagnosis, Treatment and Devices Symposium ------------------------------------------------------------------------ LUNGEVITY FOUNDATION LUNGevity 05/22/2017 $40,000.00 Foundation Science and Clinical Research Roundtable ------------------------------------------------------------------------ PRESIDENT AND FELLOWS Breast Cancer: New 05/22/2017 $20,000.00 OF HARVARD COLLEGE Horizons, Current Controversies ------------------------------------------------------------------------ NATIONAL COMPREHENSIVE 2017-2018 Monthly 05/25/2017 $50,000.00 CANCER NETWORK Oncology Tumor Boards: A Multidisciplinary Approach to Individualized Patient Care ------------------------------------------------------------------------ AMERICAN LUNG LungForce Expo 05/28/2017 $1,000.00 ASSOCIATION IN MISSOURI ------------------------------------------------------------------------ AMERICAN COLLEGE OF Cardiovascular 06/03/2017 $150,000.00 CARDIOLOGY FOUNDATION Risk in Diabetes ------------------------------------------------------------------------ AMERICAN SOCIETY FOR ASTRO 2017 59th 06/04/2017 $25,000.00 RADIATION ONCOLOGY Annual Meeting ------------------------------------------------------------------------ THE GOG FOUNDATION, 8th Semi Annual 06/04/2017 $20,000.00 INC. Meeting of NRG Oncology ------------------------------------------------------------------------ AMERICAN ACADEMY OF AAFP FMX 60-minute 06/04/2017 $33,000.00 FAMILY PHYSICIANS Interactive Lecture and 60- Minute Problem- Based Learning Workshop titled Acute Coronary Syndromes ------------------------------------------------------------------------ NORTHWESTERN UNIVERSITY 6th Annual Chicago 06/04/2017 $10,000.00 Cardiovascular Symposium ------------------------------------------------------------------------ MERCY HOSPITAL Catholic Health 06/04/2017 $5,000.00 FOUNDATION 8th Annual Cardiovascular Symposium ------------------------------------------------------------------------ AMERICAN COLLEGE OF Lung Cancer 06/06/2017 $50,000.00 CHEST PHYSICIANS Learning Track ------------------------------------------------------------------------ SOCIETY FOR 2017 Primer on 06/06/2017 $50,000.00 IMMUNOTHERAPY OF Tumor Immunology CANCER and Cancer Immunotherapy ------------------------------------------------------------------------ SOCIETY FOR 2017 Workshop on 06/07/2017 $150,000.00 IMMUNOTHERAPY OF Single Cell CANCER Techniques in Immunology and Cancer Immunotherapy ------------------------------------------------------------------------ SOCIETY FOR 2018 SITC- 06/07/2017 $120,000.00 IMMUNOTHERAPY OF AstraZeneca CANCER Postdoctoral Cancer Immunotherapy in Combination Therapies Clinical Fellowship Award ------------------------------------------------------------------------ TRANSLATIONAL RESEARCH TRIO-US AND UCLA 06/08/2017 $5,000.00 IN ONCOLOGY-US, INC. Annual Research Conference ------------------------------------------------------------------------ ACS DIVISION OF Division of 06/08/2017 $2,000.00 MEDICINAL CHEMISTRY Medicinal Chemistry Program 254th ACS National Meeting ------------------------------------------------------------------------ SAINT FRANCIS HOSPITAL 53rd Annual Robert 06/11/2017 $3,000.00 AND MEDICAL CENTER M. Jeresaty, M.D., Cardiovascular Symposium ------------------------------------------------------------------------ NYU POST-GRADUATE Women and Cancer: 06/12/2017 $5,000.00 MEDICAL SCHOOL From Screening to Survivorship ------------------------------------------------------------------------ PREVENTIVE Antiplatelet 06/12/2017 $10,000.00 CARDIOVASCULAR NURSES Therapy Post-ACS: ASSOCIATION Choosing the Right Therapy for the Right Duration ------------------------------------------------------------------------ PERSONALIZED MEDICINE Turning the Tide 06/13/2017 $10,000.00 COALITION Against Cancer Through Sustained Medical Innovation 2017 National Conference ------------------------------------------------------------------------ MEDICAL LEARNING The Present and 06/13/2017 $177,230.00 INSTITUTE the Future of Cancer Immunotherapy Biomarkers: Assessing Challenges, Opportunities, and Implications for athologists (150204581) ------------------------------------------------------------------------ AMERICAN COLLEGE OF ACEP17 06/13/2017 $15,000.00 EMERGENCY PHYSICIANS Cardiovascular Track ------------------------------------------------------------------------ BINAYTARA FOUNDATION 5th International 06/14/2017 $5,000.00 Conference on Advances in Hematology and Oncology (ICAHO 2017) ------------------------------------------------------------------------ NORTHWESTERN UNIVERSITY 19th Annual Lynn 06/14/2017 $15,000.00 Sage Breast Cancer Symposium ------------------------------------------------------------------------ AMERICAN ASSOCIATION AACR Special 06/14/2017 $35,000.00 FOR CANCER RESEARCH Conference on Tumor Immunology and Immunotherapy ------------------------------------------------------------------------ COPD FOUNDATION INC. COPD10USA 06/14/2017 $6,800.00 ------------------------------------------------------------------------ DUKE UNIVERSITY Duke Heart Center 06/15/2017 $5,000.00 General Cardiology Update--A Case- Based Review ------------------------------------------------------------------------ AMERICAN HEART 2017 TN M:L STEMI 06/19/2017 $10,000.00 ASSOCIATION Conference ------------------------------------------------------------------------ THE TRANSVERSE MYELITIS 2017 Rare Neuro- 06/19/2017 $5,000.00 ASSOCIATION immune Disorders Symposium ------------------------------------------------------------------------ INTERNATIONAL IASLC--Lung Cancer 06/19/2017 $1,605,600.00 ASSOCIATION FOR THE Education STUDY OF LUNG CANCER ------------------------------------------------------------------------ MEDICAL LEARNING Acute Coronary 06/20/2017 $125,000.00 INSTITUTE INC. Syndrome: Getting to the Heart of the Matter for Pharmacists ------------------------------------------------------------------------ USF HEALTH PROFESSIONS inPractice 06/21/2017 $30,000.00 CONFERENCING Oncology 2017- CORPORATION 2018: Breast and Gynecologic Cancers Tracks ------------------------------------------------------------------------ USF HEALTH PROFESSIONS inPractice 06/21/2017 $20,000.00 CONFERENCING Oncology 2017 CORPORATION 2018: Lung Cancer Track ------------------------------------------------------------------------ GLOBAL EDUCATION GROUP, The Role of 06/22/2017 $10,000.00 LTD. Antiplatelet Therapy in the Short- and Long- term Management of Highrisk Patients with ACS ------------------------------------------------------------------------ FEDERATION OF AMERICAN FASEB Autoimmunity- 06/22/2017 $5,000.00 SOCIETIES FOR Additional EXPERIMENTAL BIOLOGY Funding for Grant #73697 ------------------------------------------------------------------------ THE LEUKEMIA AND Precision and 06/27/2017 $25,000.00 LYMPHOMA SOCIETY, INC. emerging Medicine for Hematological Diseases ------------------------------------------------------------------------ ASSOCIATION OF ASTHMA Unraveling Current 06/27/2017 $10,000.00 EDUCATORS Asthma Challenges ------------------------------------------------------------------------ NATIONAL COMPREHENSIVE NCCN 2017 Oncology 06/27/2017 $40,000.00 CANCER NETWORK Case Manager and Medical Director Program ------------------------------------------------------------------------ COPD FOUNDATION PRAXIS and the 06/27/2017 $120,000.00 COPD Readmissions Institute ------------------------------------------------------------------------ NATIONAL KIDNEY New Paradigms in 06/28/2017 $158,250.00 FOUNDATION, INC. the Treatment of Hyperkalemia ------------------------------------------------------------------------ AMERICAN ACADEMY OF 9th Allergy, 06/28/2017 $5,000.00 PHYSICIAN ASSISTANTS Asthma and ENT IN ALLERGY, ASTHMA AND CME IMMUNOLOGY ------------------------------------------------------------------------ NATIONAL COMPREHENSIVE NCCN 2017 Congress 06/29/2017 $25,000.00 CANCER NETWORK Series : Biomarkers 101 (4 Live Webinars and 4 Enduring Webinars) ------------------------------------------------------------------------ ASSOCIATION OF Association of 06/29/2017 $10,000.00 PHYSICIAN ASSISTANTS Physician IN ONCOLOGY INC. Assistants in Oncology 20th Annual Conference ------------------------------------------------------------------------ AMERICAN COLLEGE OF TSAAI 2017 Annual 07/02/2017 $3,000.00 ALLERGY, ASTHMA AND Meeting IMMUNOLOGY ------------------------------------------------------------------------ FLORIDA ACADEMY OF Rashes, joints and 07/02/2017 $3,000.00 PHYSICIAN ASSISTANTS ANA: 2017 Lupus update ------------------------------------------------------------------------ WEILL CORNELL MEDICINE Emerging 08/01/2017 $20,000.00 Immunological Themes in Oncology, Metabolism and Inflammation ------------------------------------------------------------------------ THE DIATRIBE FOUNDATION Glycemic Outcomes 08/01/2017 $25,000.00 Beyond A1c Consensus Conference ------------------------------------------------------------------------ THE BOARD OF REGENTS OF PARP Inhibitors: 08/02/2017 $90,000.00 THE UNIVERSITY OF Their Role in the NEBRASKA MEDICAL Treatment of CENTER DBA UNMC CENTER Ovarian Cancer FOR CONTINUING EDU ------------------------------------------------------------------------ LUNGEVITY FOUNDATION HCP Attitudes 08/03/2017 $91,800.00 toward Re-biopsy of Lung Cancer Patients Project ------------------------------------------------------------------------ HEART FAILURE SOCIETY Clinical Care 08/03/2017 $150,000.00 OF AMERICA INC. Crossroads: Navigating the Intersection of Heart Failure and Diabetes ------------------------------------------------------------------------ AMERICAN ACADEMY OF 35th Annual Aspen 08/03/2017 $10,000.00 ALLERGY ASTHMA AND Allergy IMMUNOLOGY Conference ------------------------------------------------------------------------ BIOCONDUCTOR FOUNDATION Bioconductor 08/03/2017 $2,000.00 OF NA INC. Conference 2017 ------------------------------------------------------------------------ MEDICAL LEARNING Orienteering on 08/09/2017 $795,250.00 INSTITUTE, INC. the Complex Treatment Landscape for EGFR-Mutant NSCLC: Latest Evidence to Guide Clinical Decisions in Everyday Community Practice ------------------------------------------------------------------------ THE ANGIOGENESIS xME: Targeted 08/10/2017 $15,000.00 FOUNDATION Therapy, Immunotherapy, and the Chronic Lymphocytic Leukemia Microenvironment ------------------------------------------------------------------------ NATIONAL COMPREHENSIVE NCCN 12th Annual 08/21/2017 $75,000.00 CANCER NETWORK, INC. Congress: Hematologic MalignanciesT ------------------------------------------------------------------------ AMERICAN ASSOCIATION AACR-AstraZeneca 08/21/2017 $253,000.00 FOR CANCER RESEARCH Fellowships in Hematology- Oncology Research (Lymphoma) ------------------------------------------------------------------------ MEDICAL LEARNING PeerView Master 08/21/2017 $340,120.00 INSTITUTE, INC. Class and Practicum Live at IASLC 2017 CMSTO: New Options and Evolving Strategies for Hitting the Target in EGFR- Mutant NSCLC ------------------------------------------------------------------------ AMERICAN SOCIETY OF ASH Meeting on 08/22/2017 $60,000.00 HEMATOLOGY Hematologic Malignancies ------------------------------------------------------------------------ MEDICAL LEARNING Addressing Unmet 08/22/2017 $270,630.00 INSTITUTE, INC. Needs in Lung Cancer With Rational Immunotherapy- Based Approaches: Evidence and Practicalities (150204646) ------------------------------------------------------------------------ MEDICAL LEARNING Integrating 08/22/2017 $304,174.00 INSTITUTE, INC. Immunotherapy into a Multimodal Treatment Approach (150204726) ------------------------------------------------------------------------ ENDOCRINE FELLOWS Fourth Annual 08/23/2017 $250,000.00 FOUNDATION Endocrine Fellows Research Forum ------------------------------------------------------------------------ AMERICAN SOCIETY OF 59th ASH Annual 08/24/2017 $250,000.00 HEMATOLOGY Meeting ------------------------------------------------------------------------ MAYO CLINIC ARIZONA Acute and Chronic 08/31/2017 $5,000.00 Leukemias 2017 ------------------------------------------------------------------------ COLUMBIA UNIVERSITY Innovations in the 08/31/2017 $1,500.00 DEPARTMENT OF SURGERY Management of Lung Cancer: Immunotherapy, targeted therapies and minimally invasive techniques ------------------------------------------------------------------------ ANNEBERG CENTER FOR JADPRO Live at 08/31/2017 $25,000.00 HEALTH SCIENCES AT APSHO 2017: EISENHOWER Managing Side Effects of Cancer Patients Treated With Immunotherapy ------------------------------------------------------------------------ UNIVERSITY OF MARYLAND, UPDATE: Thoracic 08/31/2017 $5,000.00 SCHOOL OF MEDICINE Oncology 2017 ------------------------------------------------------------------------ BAYLOR COLLEGE OF Breast Cancer 09/03/2017 $3,000.00 MEDICINE. BREAST Research and CENTER Education Program ------------------------------------------------------------------------ SOCIETY FOR Grant Writing 09/03/2017 $10,000.00 IMMUNOTHERAPY OF Workshop CANCER ------------------------------------------------------------------------ COLUMBIA UNIVERSITY 2017 Gigi Shaw 09/07/2017 $3,500.00 COLLEGE OF PHYSICIANS Arledge AND SURGEONS, DEPT. OF Conference on SURGERY Pancreatic Disease ------------------------------------------------------------------------ LUPUS RESEARCH Lupus Research 09/11/2017 $25,000.00 ALLIANCE, INC. Alliance 2017 Annual Scientific Conference--Forum for Discovery ------------------------------------------------------------------------ DANA FARBER CANCER Dana-Farber Cancer 09/13/2017 $2,500.00 INSTITUTE Institute's 13th Annual Postdoctoral and Graduate Student Retreat ------------------------------------------------------------------------ ASSOCIATION OF The Evolving Role 09/13/2017 $20,000.00 COMMUNITY CANCER of the Oncology CENTERS Pharmacist in the Management of Non- small Cell Lung Cancer ------------------------------------------------------------------------ NATIONAL COMPREHENSIVE Pharmacy Updates: 09/14/2017 $50,000.00 CANCER NETWORK, INC. A Webinar Series ------------------------------------------------------------------------ CINCINNATI CHILDREN'S 4th CURED EGID 09/18/2017 $5,000.00 Research Conference and Patient Education Program ------------------------------------------------------------------------ JOHNS HOPKINS OncologyConsults.c 09/19/2017 $10,000.00 UNIVERSITY om Integrating Immunotherapy into SCCHN Care: Implications for the Multidisciplinary Oncology Care Team ------------------------------------------------------------------------ PROSTATE CANCER 24th Annual 09/19/2017 $20,000.00 FOUNDATION Scientific Retreat ------------------------------------------------------------------------ AMERICAN PANCREATIC 48th Annual 09/19/2017 $25,000.00 ASSOCIATION, INC. Meeting of the American Pancreatic Association ------------------------------------------------------------------------ MAYO CLINIC ARIZONA Mayo Clinic Cancer 09/20/2017 $5,000.00 Center Thoracic Oncology Update State of the Art Evaluation and Management of Thoracic Cancers ------------------------------------------------------------------------ NATIONAL COMPREHENSIVE Behind the 09/24/2017 $25,000.00 CANCER NETWORK Guidelines: FOUNDATION (NCCN) Insights into the Standard of Care in Oncology 2018 ------------------------------------------------------------------------ FOUNDATION FOR HEART 21st Annual Heart 09/25/2017 $10,000.00 FAILURE INC. Failure 2017-An Update on Therapy ------------------------------------------------------------------------ UNIVERSITY OF COLORADO/ Sex Differences 10/02/2017 $30,000.00 CENTER FOR WOMEN'S across the HEALTH RESEARCH Lifespan: A Focus on Metabolism ------------------------------------------------------------------------ LYMPHOMA RESEARCH Adherence and Oral 10/02/2017 $20,000.00 FOUNDATION Therapies in Lymphoma and CLL Workshop ------------------------------------------------------------------------ ECOG RESEARCH AND ECOG-ACRIN 2017 10/02/2017 $15,000.00 EDUCATION FOUNDATION, Fall Group INC. Meeting ------------------------------------------------------------------------ SOCIETY FOR SCAI 2017 10/02/2017 $35,000.00 CARDIOVASCULAR Interventional ANGIOGRAPHY AND Cardiology INTERVENTIONS Fellows Course FOUNDATION ------------------------------------------------------------------------ THE UNIVERSITY OF TEXAS Emerging Therapies 10/04/2017 $5,000.00 MD ANDERSON CANCER in Oncology From CENTER Phase I and Beyond ------------------------------------------------------------------------ INTERNATIONAL Best of 18th World 10/05/2017 $20,000.00 ASSOCIATION FOR THE Conference on STUDY OF LUNG CANCER Lung Cancer (WCLC) ------------------------------------------------------------------------ AMERICAN UROLOGICAL Assessing the 10/09/2017 $75,000.00 ASSOCIATION Educational Needs of Urologic Care Team in the area of Bladder Cancer and Immunotherapy ------------------------------------------------------------------------ COLORADO ALLERGY AND CAAS October 2017 10/09/2017 $3,343.10 ASTHMA SOCIETY ``State of the Art Approaches to Asthma Diagnosis and Treatment'' ------------------------------------------------------------------------ ICAHN SCHOOL OF Top Ten Advances 10/12/2017 $5,000.00 MEDICINE AT MOUNT in Clinical SINAI Cardiology ------------------------------------------------------------------------ THE MASSACHUSETTS Boston 10/12/2017 $4,000.00 GENERAL HOSPITAL Angiogenesis Meeting ------------------------------------------------------------------------ AMERICAN SOCIETY OF Anemia in Kidney 10/16/2017 $155,550.00 NEPHROLOGY Diseases: Beyond the Usual Suspects ------------------------------------------------------------------------ REGENTS OF THE Updates in 10/16/2017 $5,000.00 UNIVERSITY OF Rheumatology CALIFORNIA, UCSD 2017: Highlights OFFICE OF CME from the ACR and EULAR Meetings ------------------------------------------------------------------------ FLORIDA ACADEMY OF Acute Coronary 10/16/2017 $7,500.00 PHYSICIAN ASSISTANTS Syndrome ------------------------------------------------------------------------ NEBRASKA ACADEMY OF Acute Coronary 10/16/2017 $7,500.00 PHYSICIAN ASSISTANTS Syndrome: A Review of Diagnostic Criteria, and Treatment Options ------------------------------------------------------------------------ PEPTIDE THERAPEUTICS 12th Annual 10/18/2017 $15,000.00 FOUNDATION Peptide Therapeutics Symposium ------------------------------------------------------------------------ KEYSTONE SYMPOSIA ON Cancer 10/18/2017 $15,000.00 MOLECULAR AND CELLULAR Immunotherapy: BIOLOGY Combinations ------------------------------------------------------------------------ THE PENNSYLVANIA STATE Beyond the 10/24/2017 $30,000.00 UNIVERSITY Guidelines: Investigator Perspectives on Current Clinical Issues and Ongoing Research in the Management of Advanced Prostate Cancer-- An ISS Held as a Premium Ancillary Educational Event During the 2018 Genitourinary Cancers Symposium ------------------------------------------------------------------------ TRUSTEES OF TUFTS 2017 Tufts Cancer 10/26/2017 $2,500.00 COLLEGE Symposium, Transforming Therapeutic Outcomes: Innovations in Cancer Modeling ------------------------------------------------------------------------ MEDSTAR GEORGETOWN Lung Cancer 2017: 10/26/2017 $7,500.00 MEDICAL CENTER INC. Progress and Future Directions ------------------------------------------------------------------------ AMERICAN COLLEGE OF American College 10/29/2017 $5,000.00 TOXICOLOGY of Toxicology 38th Annual Meeting, Symposium 6: Early Career Professionals' Forum: Current Topics in Toxicology ------------------------------------------------------------------------ SOCIETY FOR SITC's connectED 11/01/2017 $500,000.00 IMMUNOTHERAPY OF CANCER ------------------------------------------------------------------------ THE BOARD OF TRUSTREES Stanford Review of 11/06/2017 $5,000.00 OF THE LELAND STANFORD the 59th Annual JUNIOR UNIVERSITY American Society of Hematology Meeting 2018 ------------------------------------------------------------------------ UNIVERSITY OF Rheumatology 11/07/2017 $15,000.00 CINCINNATI Winter Clinical Symposium 2018 (RWCS 2018) ------------------------------------------------------------------------ UT HEALTH SAN ANTONIO 40TH Annual San 11/07/2017 $75,000.00 (UTHSCSA) Antonio Breast Cancer Symposium ------------------------------------------------------------------------ THE GOG FOUNDATION INC. 9th Semi Annual 11/08/2017 $20,000.00 Meeting of NRG Oncology ------------------------------------------------------------------------ NATIONAL COMPREHENSIVE NCCN AACR ASCO 11/08/2017 $710,115.00 CANCER NETWORK, INC. Stage III NSCLC Practical Application of Immune Checkpoint Inhibition After Chemoradiotherapy ------------------------------------------------------------------------ CANCER RESEARCH CRI Irvington 11/08/2017 $50,000.00 INSTITUTE Postdoctoral Fellowship Program ------------------------------------------------------------------------ MID-ATLANTIC SECTION OF 2017 Society for 11/09/2017 $10,000.00 THE AMERICAN Basic Urologic UROLOGICAL ASSOCIATION Research (SBUR) and European Society for Urological Research (ESUR) joint Fall Symposium ------------------------------------------------------------------------ WEST PENN ALLEGHENY Twelfth Annual 11/09/2017 $8,000.00 HEALTH SYSTEM DBA Nemacolin ALLEGHENY GENERAL International HOSPITAL Asthma Conference An Interactive Forum on Patient Care, Therapy, and Research ------------------------------------------------------------------------ UNIVERSITY OF Request for 2017 11/14/2017 $5,000.00 CALIFORNIA BERKELEY Funding for the FOUNDATION Forum for Collaborative Research's Program on HBV ------------------------------------------------------------------------ AMERICAN SOCIETY FOR 2018 11/14/2017 $35,000.00 RADIATION ONCOLOGY Multidisciplinary (ASTRO) Head and Neck Cancer Symposium: Expanding Treatment Horizons ------------------------------------------------------------------------ AMERICAN SOCIETY OF Hematology 2017: 11/15/2017 $75,000.00 HEMATOLOGY the ASH Education Program ------------------------------------------------------------------------ THE UNIVERSITY OF TEXAS Leukemia Research 11/15/2017 $5,000.00 MD ANDERSON CANCER Meeting CENTER ------------------------------------------------------------------------ AMERICAN SOCIETY OF 2018 Highlights of 11/15/2017 $100,000.00 HEMATOLOGY ASHr in North America ------------------------------------------------------------------------ CONQUER CANCER 2018 Conquer 11/16/2017 $40,000.00 FOUNDATION OF THE Cancer Foundation AMERICAN SOCIETY OF of ASCO Merit CLINICAL ONCOLOGY Awards ------------------------------------------------------------------------ CONQUER CANCER 2018 ASCO-SITC 11/21/2017 $60,000.00 FOUNDATION OF THE Clinical Immuno- AMERICAN SOCIETY OF Oncology CLINICAL ONCOLOGY Symposium ------------------------------------------------------------------------ AMERICAN COLLEGE OF New York 11/21/2017 $5,000.00 CARDIOLOGY FOUNDATION Cardiovascular Symposium ------------------------------------------------------------------------ NATIONAL KIDNEY Scientific 11/22/2017 $160,000.00 FOUNDATION INC. Workshop on Change in Albuminuria and GFR as End Points for Clinical Trials in Early Stages of Chronic Kidney Disease ------------------------------------------------------------------------ MEDICAL LEARNING PeerView 11/27/2017 $50,000.00 INSTITUTE, INC. MasterClass--Prac ticum Live at ASCO GI The Quest to Win Through Science in Pancreatic Cancer From Sequencing Current Options to Testing Novel Approaches ------------------------------------------------------------------------ THE GUTHY JACKSON ECTRIMS 2017 NMO 11/29/2017 $6,000.00 CHARITABLE FOUNDATION Symposium ------------------------------------------------------------------------ AALAS FOUNDATION Student and 11/30/2017 $5,000.00 Teacher Public Educational Outreach ------------------------------------------------------------------------ GORDON RESEARCH Biology of Acute 12/01/2017 $5,000.00 CONFERENCE Respiratory Infection Gordon Research Conference ------------------------------------------------------------------------ LEUKEMIA RESEARCH Hollis Brownstein 12/03/2017 $100,000.00 FOUNDATION Research Grants Program ------------------------------------------------------------------------ AMERICAN COLLEGE OF 2017 ACR/ARHP 12/03/2017 $75,000.00 RHEUMATOLOGY Annual Meeting Lupus Educational Track ------------------------------------------------------------------------ NATIONAL JEWISH HEALTH 40th Annual 12/04/2017 $20,000.00 National Jewish Health Pulmonary and Allergy Update ------------------------------------------------------------------------ KEYSTONE SYMPOSIA ON 2018 Keystone 12/04/2017 $25,000.00 MOLECULAR AND CELLULAR Symposia BIOLOGY Directors' Fund ------------------------------------------------------------------------ AMERICAN DIABETES Diabetes is 12/04/2017 $40,568.50 ASSOCIATION Primary Digital Program on Cardiovascular Risk ------------------------------------------------------------------------ AMERICAN COLLEGE OF 2017 ACLAM Grants 12/04/2017 $4,000.00 LABORATORY ANIMAL MEDICINE ------------------------------------------------------------------------ SOUTHERN MEDICAL Medical Dilemmas 12/05/2017 $2,500.00 ASSOCIATION in Patient Care Conference ------------------------------------------------------------------------ THE NORTH AMERICAN 3RS Virtual Education 12/06/2017 $8,000.00 COLLABORATIVE Community Support ------------------------------------------------------------------------ CONQUER CANCER 2018 Conquer 12/10/2017 $500,000.00 FOUNDATION OF THE Cancer Foundation AMERICAN SOCIETY OF of ASCO Mission CLINICAL ONCOLOGY Endowment ------------------------------------------------------------------------ CONQUER CANCER 2018 Genitourinary 12/10/2017 $60,000.00 FOUNDATION OF THE (GU) Cancers AMERICAN SOCIETY OF Symposium: CLINICAL ONCOLOGY Translating Evidence to Multidisciplinary Care ------------------------------------------------------------------------ CONQUER CANCER 2018 Conquer 12/10/2017 $256,000.00 FOUNDATION OF THE Cancer Foundation AMERICAN SOCIETY OF of ASCO Young CLINICAL ONCOLOGY Investigator Award (YIA) ------------------------------------------------------------------------ REGENTS OF THE 15th Annual 12/10/2017 $40,000.00 UNIVERSITY OF Nephrology Young CALIFORNIA Investigators Forum ------------------------------------------------------------------------ JOHNS HOPKINS Mid Atlantic 12/10/2017 $50,000.00 UNIVERSITY SCHOOL OF Nephrology Young MEDICINE Investigators Forum ------------------------------------------------------------------------ ILLINOIS ACADEMY OF The 12th Annual 12/11/2017 $54,771.32 FAMILY PHYSICIANS Chief Residents Summit on Intensifying Diabetes Management ------------------------------------------------------------------------ AMERICAN COLLEGE OF 2018 ACR 12/11/2017 $50,000.00 RHEUMATOLOGY Rheumatology Courses ------------------------------------------------------------------------ JOHNS HOPKINS FastForward 12/12/2017 $25,000.00 UNIVERSITY Corporate Sponsorship ------------------------------------------------------------------------ THE DEUEL CONFERENCE ON The 2018 Deuel 12/13/2017 $5,000.00 LIPIDS Conference on Lipids ------------------------------------------------------------------------ FEDERATION OF AMERICAN FASEB SRC 12/13/2017 $5,000.00 SOCIETIES FOR Immunoreceptors EXPERIMENTAL BIOLOGY and Immunotrerapy (FASEB) ------------------------------------------------------------------------ UNIVERSITY OF Request for 2018 12/13/2017 $10,000.00 CALIFORNIA BERKELEY Funding for the FOUNDATION Forum for Collaborative Research's ------------------------------------------------------------------------ GORDON RESEARCH Gordon Conference 12/14/2017 $5,000.00 CONFERENCE on Drug Resistance 2018 ------------------------------------------------------------------------ ASSOCIATION FOR WOMEN Innovation and 12/17/2017 $25,000.00 IN SCIENCE Inclusion: Women at the Forefront of STEM ------------------------------------------------------------------------ VIRGINIA BIOTECHNOLOGY MedImmune 12/17/2017 $25,000.00 ASSOCIATION Chairman's Circle Membership ------------------------------------------------------------------------ FEDERATION OF AMERICAN The Lung 12/20/2017 $5,000.00 SOCIETIES FOR Epithelium in EXPERIMENTAL BIOLOGY Health and SRC Disease ------------------------------------------------------------------------ ENGINEERING CONFERENCES Cell Culture 12/21/2017 $10,000.00 INTERNATIONAL Engineering XVI Conference ------------------------------------------------------------------------ PENNYSLVANIA SOCIETY 2018 PSBR 12/24/2017 $2,000.00 FOR BIOMEDICAL Membership RESEARCH ------------------------------------------------------------------------ NATIONAL ACADEMY OF Roundtable in 12/24/2017 $4,000.00 SCIENCES Science and Welfare of Laboratory Animal Use ------------------------------------------------------------------------ CONQUER CANCER 2018 01/02/2018 $30,000.00 FOUNDATION OF THE Gastrointestinal AMERICAN SOCIETY OF (GI) Cancers CLINICAL ONCOLOGY Symposium: Multidisciplinary Care: Local Practice, Global Outcomes ------------------------------------------------------------------------ AMERICAN ASSOCIATION AACR-IASLC Joint 01/02/2018 $25,000.00 FOR CANCER RESEARCH Conference on the Molecular Origins of Lung Cancer ------------------------------------------------------------------------ NATIONAL JEWISH HEALTH 14th Annual 01/02/2018 $299,608.49 Respiratory Disease Young Investigators' Forum ------------------------------------------------------------------------ THE CHEST FOUNDATION CHEST Foundation 01/02/2018 $55,000.00 Research Award in COPD ------------------------------------------------------------------------ INTERNATIONAL Implementation of 01/04/2018 $300,000.00 ASSOCIATION FOR THE diagnostic and STUDY OF LUNG CANCER molecular guidelines in low- middle income regions for targeted therapies in NSCLC ------------------------------------------------------------------------ UNIVERSITY OF NORTH 9th International 01/09/2018 $2,500.00 CAROLINA AT CHAPEL Symposia for the HILL CGRP Family Peptides Conference ------------------------------------------------------------------------ UNIVERSITY OF The Intersection 01/14/2018 $95,000.00 CINCINNATI Between COPD and Cardiometabolic Comorbidities ------------------------------------------------------------------------ NATIONAL KIDNEY 13th Annual 01/14/2018 $50,000.00 FOUNDATION INC. National Young Investigator Forum ------------------------------------------------------------------------ AMERICAN COLLEGE OF WSAAI 2018: 56th 01/17/2018 $15,000.00 ALLERGY, ASTHMA AND Annual Scientific IMMUNOLOGY (ACAAI) Session ------------------------------------------------------------------------ AMERICAN ASSOCIATION AACR-SNMMI Joint 01/18/2018 $10,000.00 FOR CANCER RESEARCH Conference on State-of-the-Art Molecular Imaging in Cancer Biology and Therapy ------------------------------------------------------------------------ THE UNIVERSITY OF TEXAS 2018 Oncologic 01/23/2018 $10,000.00 MD ANDERSON CANCER Emergency CENTER Medicine Conference ------------------------------------------------------------------------ NATIONAL ASSOCIATION OF Exploring the 01/25/2018 $35,000.00 MANAGED CARE Challenges of PHYSICIANS Severe Asthma: Understanding Appropriate Treatment Strategies for Improved Patient Outcomes ------------------------------------------------------------------------ CANCER RESEARCH Cancer 02/05/2018 $10,000.00 INSTITUTE Immunotherapy Consortium Workshop ------------------------------------------------------------------------ ANNENBERG CENTER FOR Advancing 02/11/2018 $200,000.00 HEALTH SCIENCES AT Knowledge to EISENHOWER Practice Optimizing Severe Asthma Care in the Age of Biologics ------------------------------------------------------------------------ PENNSYLVANIA STATE PeerView Live at 02/12/2018 $104,507.00 UNIVERSITY the 2018 ASCO Annual Meeting, The Arrival of Novel Agent Classes in B-Cell Non-Hodgkin Lymphoma: A Personal Guide to Integrating New Therapy into Patient Care (150204877) ------------------------------------------------------------------------ ANNENBERG CENTER FOR Clinical Advances 02/13/2018 $75,000.00 HEALTH SCIENCES and Case Studies in Immune Checkpoint Inhibitors in Oncology ------------------------------------------------------------------------ NATIONAL COMPREHENSIVE NCCN 2018 Oncology 02/14/2018 $35,000.00 CANCER NETWORK, INC. Fellows Program: New Horizons in Quality Cancer CareT at the NCCN 23rd Annual Conference ------------------------------------------------------------------------ INDY HEMATOLOGY 2018 Indy 02/14/2018 $10,000.00 EDUCATION, INC. Hematology Review ------------------------------------------------------------------------ JOHNS HOPKINS 14th International 02/14/2018 $20,000.00 UNIVERSITY Symposium on Sjogrens Syndrome ------------------------------------------------------------------------ SCRIPPS HEALTH Scripps 38th 02/14/2018 $25,000.00 Annual Clinical Hematology and Oncology Conference ------------------------------------------------------------------------ THE CHEST FOUNDATION CHEST Foundation 02/14/2018 $35,000.00 Research Award in Severe Asthma ------------------------------------------------------------------------ ANNENBERG CENTER FOR Clinical 02/14/2018 $100,000.00 HEALTH SCIENCES Management of Novel Therapies for Hematological Malignancies (5 Regional lectures by APSHO/JADPRO) ------------------------------------------------------------------------ MEDICAL LEARNING PeerView inVision, 02/14/2018 $64,125.00 INSTITUTE, INC. ``Targeted Treatment in Severe Asthma: Moving Toward Precision Medicine'' ------------------------------------------------------------------------ COLLEGIUM 32nd Symposium of 02/14/2018 $10,000.00 INTERNATIONALE the Collegium ALLERGOLOGICUM Internationale Allergologicum ------------------------------------------------------------------------ AMERICAN SOCIETY FOR Immuno-Oncology: 02/14/2018 $60,490.00 CLINICAL PATHOLOGY Scientific Updates ------------------------------------------------------------------------ NATIONAL JEWISH HEALTH COPD Basics: An 02/14/2018 $100,000.00 Integrated Approach to Best Practices in Five Healthcare Networks ------------------------------------------------------------------------ MAYO CLINIC ARIZONA Clinical 02/14/2018 $15,000.00 Multidisciplinary Hematology and Oncology: The 15th Annual Review ------------------------------------------------------------------------ INTERNATIONAL 18th Targeted 02/14/2018 $55,100.00 ASSOCIATION FOR THE Therapy meeting STUDY OF LUNG CACEER ------------------------------------------------------------------------ MEDICAL LEARNING PeerView Master 02/14/2018 $299,330.00 INSTITUTE, INC. Class and Practicum Live at CHEST 2018, ``New Avenues in Asthma Management: Finding the Right Patients for Targeted Therapies'' (150205033) ------------------------------------------------------------------------ NATIONAL KIDNEY Chronic 02/15/2018 $232,979.00 FOUNDATION INC. Hyperkalemia Management and Outcomes in CKD ------------------------------------------------------------------------ ALZHEIMER'S ASSOCIATION Alzheimer's 02/15/2018 $45,000.00 Association International Conference, AAIC 2018 ------------------------------------------------------------------------ ASTHMA AND ALLERGY Wheezin', Sneezin' 02/16/2018 $10,000.00 FOUNDATION OF AMERICA-- and Itchin' in ALASKA CHAPTER Alaska ------------------------------------------------------------------------ NATIONAL ASSOCIATION OF New Agents and 02/18/2018 $35,000.00 MANAGED CARE Emerging PHYSICIANS Strategies in Advanced Breast Cancer: Patient- Centric Navigation in the Age of Personalized Care ------------------------------------------------------------------------ THE PENNSYLVANIA STATE PeerView inPlay, 02/18/2018 $145,730.00 UNIVERSITY ``The Role of the Eosinophil in COPD: Implications for Personalized Care and Novel Treatments'' (150205058) ------------------------------------------------------------------------ DUKE UNIVERSITY 3rd Annual Duke 02/19/2018 $2,500.00 Heart Center/DCRI Fellows' Presentation Skills Course ------------------------------------------------------------------------ NATIONAL ASSOCIATION OF Novel Treatment 02/19/2018 $35,000.00 MANAGED CARE Strategies in the PHYSICIANS, INC. Management of Ovarian Cancer: A Closer Look at the Role of PARP Inhibitors ------------------------------------------------------------------------ AMERICAN THORACIC ATS 2018 Fellows 02/19/2018 $10,000.00 SOCIETY INC. Track Symposium ------------------------------------------------------------------------ MEDSTAR WASHINGTON Cardiovascular 02/20/2018 $30,000.00 HOSPITAL CENTER Research Technologies (CRT) Annual Meeting ------------------------------------------------------------------------ DUKE UNIVERSITY The Southeastern 02/21/2018 $2,500.00 Fellows Research Skills and Training Workshop ------------------------------------------------------------------------ AMERICAN THORACIC ATS 2018 02/21/2018 $30,000.00 SOCIETY INC. International Conference--Selec ted Sessions in COPD ------------------------------------------------------------------------ SCRIPPS HEALTH 15th Annual 02/22/2018 $25,000.00 Fundamentals of Diabetes Management ------------------------------------------------------------------------ AMERICAN ASSOCIATION FDA-AACR-ASTRO: 02/22/2018 $25,000.00 FOR CANCER RESEARCH Clinical Development of Drug-Radiotherapy Combinations Workshop ------------------------------------------------------------------------ AMERICAN ASSOCIATION Advances in 02/25/2018 $25,000.00 FOR CANCER RESEARCH Malignant Lymphoma (AACR/ ICML ``off year'' conference in US) ------------------------------------------------------------------------ BLADDER CANCER ADVOCACY 2018 Bladder 02/25/2018 $35,000.00 NETWORK Cancer Think Tank ------------------------------------------------------------------------ GORDON RESEARCH 2018 Gordon 02/27/2018 $5,000.00 CONFERENCE Research Council on New Antibiotic Discovery and Development ------------------------------------------------------------------------ RUTGERS, THE STATE Treat-to-Target 02/28/2018 $124,857.00 UNIVERSITY OF NEW and Targeted JERSEY Therapy: The Evolving State of Systemic Lupus Erythematosus Patient Care ------------------------------------------------------------------------ AMERICAN DIABETES Diabetes is 03/01/2018 $300,000.00 ASSOCIATION Primary Core Programs ------------------------------------------------------------------------ AMERICAN ASSOCIATION AACR Annual 03/01/2018 $225,000.00 FOR CANCER RESEARCH Meeting--2018 ------------------------------------------------------------------------ NATIONAL JEWISH HEALTH A Severe Asthma 03/01/2018 $322,170.00 Roadmap for Improved Diagnosis and Personalized Treatment--A Guided Workflow ------------------------------------------------------------------------ AMERICAN ASSOCIATION OF California Chapter 03/01/2018 $10,000.00 CLINICAL of the American ENDOCRINOLOGITS Association of Clinical Endocrinologists Presents Hot Topics in Diabetes and Endocrinology for Primary Care 2018 Series ------------------------------------------------------------------------ NATIONAL COMPREHENSIVE NCCN 23rd Annual 03/02/2018 $100,000.00 CANCER NETWORK, INC. Conference: Improving the Quality, Effectiveness, and Efficiency of Cancer CareTM ------------------------------------------------------------------------ EASTERN VIRGINIA Turning the Tide 03/04/2018 $5,000.00 MEDICAL SCHOOL on Diabetes 2018 ------------------------------------------------------------------------ THE UNIVERSITY OF 15th International 03/05/2018 $25,000.00 CHICAGO Ultmann Chicago Lymphoma Symposium ------------------------------------------------------------------------ AMERICAN ASSOCIATION OF Innovating 03/05/2018 $300,000.00 CLINICAL Diabetes Care-Use ENDOCRINOLOGISTS of Real-Time Data to Transform Clinical Practice and Optimize Patient Glucose Management ------------------------------------------------------------------------ CARDIOVASCULAR RESEARCH 24th Annual 03/05/2018 $10,000.00 FOUNDATION Interventional Cardiology Fellows Course ------------------------------------------------------------------------ AMERICAN PHARMACISTS APhA2018 Your 03/05/2018 $5,000.00 ASSOC Annual Diabetes Update ------------------------------------------------------------------------ CARDIOVASCULAR RESEARCH DAPT Dilemmas: A 03/05/2018 $20,000.00 FOUNDATION Case-Based Roundtable at Fellows 2018 ------------------------------------------------------------------------ AMERICAN UROLOGICAL Japanese 03/05/2018 $40,000.00 ASSOCIATION Urological Association (JUA) Meeting ------------------------------------------------------------------------ NATIONAL COMPREHENSIVE NCCN Foundation 03/06/2018 $171,801.00 CANCER NETWORK, INC. Young Investigator Awards ------------------------------------------------------------------------ PURDUE UNIVERSITY Can You Do It 03/06/2018 $377,342.00 OFFICE OF CONTINUING Better?--A Unique PROFESSIONAL EDUCATION Approach to Enabling Improved Asthma Management ------------------------------------------------------------------------ INTERNATIONAL IASLC Workshop on 03/06/2018 $25,000.00 ASSOCIATION FOR THE Neopadjuvant STUDY OF LUNG CANCER Therapy in Lung Cancer ------------------------------------------------------------------------ UNT HEALTH SCIENCE Filling the Gaps 03/07/2018 $4,750.00 CENTER in Asthma Care-- Lessons Learned from Asthma411 ------------------------------------------------------------------------ ANNENBERG CENTER FOR Updates in 03/07/2018 $155,000.00 HEALTH SCIENCES AT Precision EISENHOWER Medicine Elevating the Treatment of Severe, Eosinophilic Asthma ------------------------------------------------------------------------ AMERICAN ASSOCIATION OF 27th Annual 03/07/2018 $63,052.00 CLINICAL Scientific and ENDOCRINOLOGITS Clinical Congress--Diabete s Sessions ------------------------------------------------------------------------ NATIONAL COMPREHENSIVE Support for NCCN 03/08/2018 $60,000.00 CANCER NETWORK Distribution of the NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelinesr) for Management of Immunotherapy- Related Toxicities Pocket Guides ------------------------------------------------------------------------ BOARD OF REGENTS OF THE 2018 Pan Pacific 03/11/2018 $125,000.00 UNIVERSITY OF NEBRASKA Lymphoma Conference ------------------------------------------------------------------------ SCRIPPS HEALTH Fifth Annual 03/11/2018 $5,000.00 Clinical Advances in Heart Failure and Arrhythmias ------------------------------------------------------------------------ NORTHEAST GEORGIA 10th Annual 03/12/2018 $2,500.00 MEDICAL CENTER Northeast Georgia STEMI Summit ------------------------------------------------------------------------ HEMATOLOGY/ONCOLOGY HOPA 14th Annual 03/12/2018 $30,000.00 PHARMACY ASSOCIATION Conference ------------------------------------------------------------------------ CONQUER CANCER 2018 ASCO Annual 03/12/2018 $20,000.00 FOUNDATION OF THE Meeting Breast AMERICAN SOCIETY OF Cancer Track CLINICAL ONCOLOGY ------------------------------------------------------------------------ CONQUER CANCER 2018 ASCO Annual 03/12/2018 $30,000.00 FOUNDATION OF THE Meeting AMERICAN SOCIETY OF Genitourinary CLINICAL ONCOLOGY Cancer Tracks Bundle: Prostate and Nonprostate ------------------------------------------------------------------------ THE GUTHY JACKSON The Guthy-Jackson 03/12/2018 $25,000.00 CHARITABLE FOUNDATION Industry Council ------------------------------------------------------------------------ REGENTS OF THE Making the 03/13/2018 $200,000.00 UNIVERSITY OF Connection CALIFORNIA Between Patients and Providers: A Comprehensive Overview of the Modern Treatment Strategies For People With Type 1 and Type 2 Diabetes ------------------------------------------------------------------------ NATIONAL KIDNEY Cardiovascular 03/13/2018 $232,979.00 FOUNDATION Risk in Patients with Chronic Kidney Disease (CKD): The Impact of Anemia ------------------------------------------------------------------------ ACADEMY OF MANAGED CARE The Immuno- 03/13/2018 $35,000.00 PHARMACY Oncology Pipeline and the Managed Care Considerations ------------------------------------------------------------------------ INTERNATIONAL IASLC 03/13/2018 $25,000.00 ASSOCIATION FOR THE Immunotherapy STUDY OF LUNG CANCER Meeting ------------------------------------------------------------------------ ACS DIVISION OF 255th ACS National 03/13/2018 $5,000.00 BIOCHEMICAL TECHNOLOGY Meeting and Exposition (BIOT Division) ------------------------------------------------------------------------ AMERICAN ASSOCIATION 12th Biennial 03/14/2018 $15,000.00 FOR CANCER RESEARCH Ovarian Cancer Research Symposium ------------------------------------------------------------------------ AMERICAN HEART Arteriosclerosis, 03/18/2018 $2,000.00 ASSOCIATION Thrombosis and Vascular Biology | Peripheral Vascular Disease 2018Scientific Sessions, Vascular Discovery: From Genes to Medicine ------------------------------------------------------------------------ RILITE FOUNDATION Lupus 21st Century 03/18/2018 $25,000.00 2018 Conference ------------------------------------------------------------------------ RHEUMATOLOGIC 4th International 03/19/2018 $10,000.00 DERMATOLOGY SOCIETY Conference on INC. Cutaneous Lupus Erythematosus ------------------------------------------------------------------------ HOWARD UNIVERSITY 13th Annual 03/19/2018 $2,500.00 Kenneth Austin Rheumatology Symposium ------------------------------------------------------------------------ SOCIETY OF GYNECOLOGIC SGO Lunch and 03/20/2018 $125,000.00 ONCOLOGY Learn Contemporary Ovarian Cancer: Keys to Therapies and Integrated Learning ------------------------------------------------------------------------ LYMPHOMA RESEARCH Mantle Cell 03/20/2018 $20,000.00 FOUNDATION Lymphoma Scientific Workshop ------------------------------------------------------------------------ CANCER MOLECULAR Molecular 03/21/2018 $5,000.00 THERAPEUTICS RESEARCH Therapeutics of ASSOCIATION Cancer Research Conference 2018 ------------------------------------------------------------------------ PREVENTIVE PCNA's 24th Annual 03/22/2018 $10,000.00 CARDIOVASCULAR NURSES Symposium ASSOCIATION ------------------------------------------------------------------------ ASPEN LUNG CONFERENCE Thomas Petty Aspen 03/22/2018 $25,000.00 Lung Conference/ Translating Resilience and Pathogenesis to Personalized Therapy for COPD ------------------------------------------------------------------------ ANNENBERG CENTER FOR Master Class for 03/22/2018 $24,246.27 HEALTH SCIENCES Oncologists--Hema tology Track ------------------------------------------------------------------------ NATIONAL ASSOCIATION OF Clinical Advances 03/25/2018 $15,000.00 MANAGED CARE in the Diagnosis, PHYSICIANS, INC. Treatment and Management of COPD ------------------------------------------------------------------------ FOUNDATION FOR SURGICAL American Head and 03/25/2018 $15,000.00 FELLOWSHIPS Neck Society Annual Meeting-- Evaluating Head and Neck Cancer Care Through Evidence Based Medicine ------------------------------------------------------------------------ DUKE UNIVERSITY Duke Debates: 03/25/2018 $15,000.00 Controversies in the Management of Patients with Hematologic Malignancies ------------------------------------------------------------------------ ICAHN SCHOOL OF Mount Sinai 03/29/2018 $7,500.00 MEDICINE AT MOUNT Division of SINAI Occupational Medicine Seminar Series ------------------------------------------------------------------------ GORDON RESEARCH Gordon Research 04/01/2018 $2,500.00 CONFERENCE Conference: Mutagenesis--Mech anisms of Intrinsic and Induced Genome Instability ------------------------------------------------------------------------ THE UNIVERSITY OF Frontiers in 04/02/2018 $25,000.00 CHICAGO Precision Medicine for Inherited Cancers: From Risk Assessment to Targeted Therapies ------------------------------------------------------------------------ THE PENNSYLVANIA STATE PeerView Live: 04/02/2018 $73,575.00 UNIVERSITY ``Unraveling the Complex Treatment Landscape for Prostate Cancer: Guidance for Delivering Evidence-Based, Patient-Centered Care'' (150204517) ------------------------------------------------------------------------ GORDON RESEARCH 2018 Gordon 04/03/2018 $2,500.00 CONFERENCES Research Conference on Medicinal Chemistry ------------------------------------------------------------------------ CLEVELAND CLINIC 2018 Cleveland 04/03/2018 $5,000.00 EDUCATION FOUNDATION Breast Cancer Summit: Collaborating for a Cure ------------------------------------------------------------------------ THE PENNSYLVANIA STATE New Directions in 04/04/2018 $124,611.00 UNIVERSITY the Management of Recurrent Ovarian Cancer: Focus on PARP Inhibitors ------------------------------------------------------------------------ ASSOCIATION FOR Advancing Patient 04/04/2018 $416,900.00 MOLECULAR PATHOLOGY Care in NSCLC: Breaking Down Barriers ------------------------------------------------------------------------ CLEVELAND CLINIC 2018 Diabetes Day 04/04/2018 $5,000.00 EDUCATIONAL FOUNDATION 23rd Annual Symposium New Frontiers in Diabetes ------------------------------------------------------------------------ MEDICAL LEARNING PeerView Master 04/04/2018 $370,100.00 INSTITUTE, INC. Class and Practicum Live at ASH 2018: ``Exploring the Present and Future of BTK Inhibition in B- cell malignancies: Expert Insights on Practical Implications for Patient Management'' (150205092) ------------------------------------------------------------------------ AMERICAN UROLOGICAL AUA2018 04/04/2018 $150,000.00 ASSOCIATION Highlights: Immunotherapy in GU Cancer ------------------------------------------------------------------------ ANNENBERG CENTER FOR Master Class for 04/05/2018 $19,391.02 HEALTH SCIENCES Oncologists--Wome n's Cancer Track ------------------------------------------------------------------------ FRIENDS OF CANCER Friends of Cancer 04/08/2018 $100,000.00 RESEARCH 2018 Research Programs ------------------------------------------------------------------------ THE HOPE FOUNDATION 2018 SWOG Group 04/08/2018 $10,000.00 Meetings ------------------------------------------------------------------------ CONQUER CANCER 2018 ASCO Annual 04/09/2018 $45,000.00 FOUNDATION OF THE Meeting AMERICAN SOCIETY OF Gynecologic CLINICAL ONCOLOGY Cancer Track ------------------------------------------------------------------------ LAHEY CLINIC HOSPITAL, Cardiovascular 04/09/2018 $5,000.00 INC. Disease State of the Art 2018 ------------------------------------------------------------------------ BOARD OF REGENTS FOR Dissecting the 04/11/2018 $75,000.00 UNIVERSITY OF NEBRASKA Decision: Documenting and Discussing the Clinical Practice Patterns of Hematologic Oncology Investigators in the Management of Chronic Lymphocytic Leukemia--An ISS Held in Conjunction with the 2018 Pan Pacific Lymphoma Conference ------------------------------------------------------------------------ TRUSTEES OF BOSTON CVD AND RENAL 04/11/2018 $109,420.00 UNIVERSITY DISEASE IN T2DM: Pivotal Role of Physician Assistants in Patient Management ------------------------------------------------------------------------ CONQUER CANCER 2018 Conquer 04/12/2018 $253,000.00 FOUNDATION OF THE Cancer Foundation AMERICAN SOCIETY OF of ASCO Career CLINICAL ONCOLOGY Development Award (CDA) ------------------------------------------------------------------------ AMERICAN COLLEGE OF CHEST 2018 Post 04/12/2018 $25,000.00 CHEST PHYSICIANS Graduate Program on Difficult to Treat Asthma ------------------------------------------------------------------------ ECOG RESEARCH AND ECOG-ACRIN 2018 04/12/2018 $5,000.00 EDUCATION FOUNDATION, Spring Group INC. Meeting ------------------------------------------------------------------------ LUPUS FOUNDATION OF NEW Lupus Medical and 04/15/2018 $5,000.00 ENGLAND Educational Symposim ------------------------------------------------------------------------ HEART FAILURE SOCIETY Future Leaders in 04/16/2018 $10,000.00 OF AMERICA INC. Heart Failure Symposium ------------------------------------------------------------------------ AMERICAN ACADEMY OF CME Applying the 04/17/2018 $313,595.00 INC. Latest Evidence to Improve Care for Patients with HR+/HER2- Metastatic Breast Cancer ------------------------------------------------------------------------ PRESIDENT AND FELLOWS Practical 04/17/2018 $5,000.00 OF HARVARD COLLEGE Considerations ACTING THROUGH THE and Rationale for DEPARTMENT OF GCE Immunotherapy 2018 ------------------------------------------------------------------------ AMERICAN ASSOCIATION OF AACE 27th Annual 04/17/2018 $30,000.00 CLINICAL Scientific & ENDOCRINOLOGITS Clinical Congress--Cardiov ascular Track ------------------------------------------------------------------------ METABOLIC ENDOCRINE 2nd Annual Heart 04/18/2018 $50,000.00 EDUCATION FOUNDATION in Diabetes ------------------------------------------------------------------------ SOCIETY FOR SCAI 2018 04/18/2018 $40,000.00 CARDIOVASCULAR Scientific ANGIOGRAPHY AND Sessions INTERVENTIONS featuring FOUNDATION Controversies in Interventional Pharmacology ------------------------------------------------------------------------ AMERICAN HEART STEMI Protocol 04/18/2018 $3,730.00 ASSOCIATION Stakeholder Education ------------------------------------------------------------------------ ALZHEIMER'S ASSOCIATION 2018 Research 04/19/2018 $50,000.00 Roundtable ------------------------------------------------------------------------ PURDUE UNIVERSITY Critical 04/23/2018 $575,210.00 Conversations on Bruton's Tyrosine Kinase Inhibitor Development and Use in B-Cell Malignancies (CCO GR Pgm) ------------------------------------------------------------------------ AMERICAN COLLEGE OF Severe Asthma 04/23/2018 $60,000.00 ALLERGY, ASTHMA AND Shared Decision IMMUNOLOGY Making Tool Instructional Video ------------------------------------------------------------------------ AMERICAN COLLEGE OF Symposium--A 04/23/2018 $80,375.00 ALLERGY, ASTHMA AND Personalized IMMUNOLOGY Approach to Managing Patients with Uncontrolled Asthma / Shifting Paradigms in Management of Severe Asthma: Pathogenesis, Phenotypes and Personalized Medicine ------------------------------------------------------------------------ MEDSTAR HEALTH, INC. 2018 MedStar 04/24/2018 $15,000.00 Health System Prostate Cancer Annual Meeting ------------------------------------------------------------------------ UT HEALTH SAN ANTONIO 3rd Annual Cardio 04/24/2018 $5,000.00 Renal Connections ------------------------------------------------------------------------ MEDSTAR HEALTH, INC. Enhancing Health 04/24/2018 $10,000.00 System Initiatives Utilizing Clinical Advances to Optimize the Diagnosis and Treatment of Prostate Cancer ------------------------------------------------------------------------ NATIONAL ASSOCIATION OF Best Practices in 04/25/2018 $35,000.00 MANAGED CARE the Management of PHYSICIANS, INC. Advanced Non- Small Cell Lung Cancer (NSCLC): Individualizing Therapy for Optimized Patient Outcomes ------------------------------------------------------------------------ TRUSTEES OF BOSTON CVD AND RENAL 04/25/2018 $49,000.00 UNIVERSITY DISEASE IN T2DM: Individualizing Therapeutic Options to Reduce Comorbid Risk ------------------------------------------------------------------------ CONQUER CANCER 2018 Best of ASCO 04/25/2018 $120,000.00 FOUNDATION OF THE Meetings AMERICAN SOCIETY OF CLINICAL ONCOLOGY ------------------------------------------------------------------------ AMERICAN CHEMICAL Recovery of 04/26/2018 $10,000.00 SOCIETY, DIVISION OF Biological BIOCHEMICAL Products XVIII TECHNOLOGY, RECOVERY Conference OF BIOLOGICAL PRODUCTS ------------------------------------------------------------------------ AMERICAN RADIUM SOCIETY American Radium 04/26/2018 $10,000.00 Society 100th Annual Meeting ------------------------------------------------------------------------ VANDERBILT UNIVERSITY Midwest Islet Club 04/26/2018 $2,500.00 Meeting ------------------------------------------------------------------------ WEST PENN ALLEGHENY 2018 04/29/2018 $5,000.00 HEALTH SYSTEM, INC. Cardiovascular DBA ALLEGHENY GENERAL Medicine Update HOSPITAL Conference ------------------------------------------------------------------------ PRESIDENT AND FELLOWS Diabetes Update 04/30/2018 $5,000.00 OF HARVARD COLLEGE 2018 ACTING THROUGH THE DEPARTMENT OF GCE ------------------------------------------------------------------------ ASPEN CANCER CONFERENCE 33rd Aspen Cancer 04/30/2018 $10,000.00 Conference ------------------------------------------------------------------------ TRUSTEES OF THE 6th Annual 04/30/2018 $20,000.00 UNIVERSITY OF Scientific PENNSYLVANIA/PERELMAN Symposium: BRCA1, SCHOOL OF MEDICINE AT BRCA2 and Beyond: THE UNIVERSITY OF PA An Update on Hereditary Cancer ------------------------------------------------------------------------ ASSOCIATION OF AMERICAN 2018 AACI/CCAF 05/01/2018 $15,000.00 CANCER INSTITUTES Annual Meeting ------------------------------------------------------------------------ ONCOLOGY NURSING 2018 ONS Annual 05/01/2018 $50,000.00 SOCIETY Congress and two Regional Conferences ------------------------------------------------------------------------ TRUSTEES OF THE 2018 New Advances 05/03/2018 $10,000.00 UNIVERSITY OF in Lung Cancer: PENNSYLVANIA/PERELMAN Stretching the SCHOOL OF MEDICINE AT Envelope THE UNIVERSITY OF PA ------------------------------------------------------------------------ HEMATOLOGY ONCOLOGY Immuno oncology 05/06/2018 $35,000.00 PHARMACY ASSOCIATION Educational Modules for Oncology Pharmacists ------------------------------------------------------------------------ CANCER RESEARCH 2018 05/06/2018 $50,000.00 INSTITUTE International Cancer Immunotherapy Conference ------------------------------------------------------------------------ AMERICAN ASSOCIATION AACR Pancreatic 05/06/2018 $25,000.00 FOR CANCER RESEARCH Cancer: Advances in Science and Clinical Care ------------------------------------------------------------------------ ALLIANCE FOR CLINICAL 2018 Group 05/07/2018 $40,000.00 TRIALS IN ONCOLOGY Meetings FOUNDATION ------------------------------------------------------------------------ AMERICAN THORACIC ATS 2018 05/07/2018 $40,000.00 SOCIETY INC. International Conference--Selec ted Sessions in Lung Cancer ------------------------------------------------------------------------ AMERICAN SOCIETY OF 2018 ASH Meeting 05/08/2018 $50,000.00 HEMATOLOGY on Lymphoma Biology ------------------------------------------------------------------------ LUNGEVITY FOUNDATION LUNGevity 05/08/2018 $50,000.00 Foundation Scientific and Clinical Roundtable-- Streamlining Clinical Trials 2018 ------------------------------------------------------------------------ HEMATOLOGY/ONCOLOGY HOPA Early Career 05/08/2018 $60,000.00 PHARMACY ASSOCIATION Research Grant ------------------------------------------------------------------------ MEDICAL LEARNING PeerView Live at 05/09/2018 $323,020.00 INSTITUTE, INC. ASTRO 2018--The Era of Immunotherapy in Stage III NSCLC (150205115) ------------------------------------------------------------------------ TRUSTEES OF THE 2018 Breast Cancer 05/09/2018 $5,000.00 UNIVERSITY OF Clinical Case PENNSYLVANIA/PERELMAN Series: The Year SCHOOL OF MEDICINE AT in Review THE UNIVERSITY OF PA ------------------------------------------------------------------------ HEART FAILURE SOCIETY 2018 HFSA Board 05/09/2018 $15,000.00 OF AMERICA INC. Certification Review Course in Advanced Heart Failure and Transplant Cardiology ------------------------------------------------------------------------ SOCIETY FOR Immuno-Oncology 05/10/2018 $25,000.00 IMMUNOTHERAPY OF Biomarkers State CANCER of the Art ------------------------------------------------------------------------ AMERICAN ACADEMY OF AAPA 2018 Annual 05/10/2018 $10,000.00 PHYSICIAN ASSISTANTS Conference ------------------------------------------------------------------------ HDL WORKSHOP HDL Workshop 2018 05/10/2018 $5,000.00 ------------------------------------------------------------------------ LUPUS RESEARCH Lupus Research 05/10/2018 $25,000.00 ALLIANCE, INC. Alliance 2018 Annual Scientific Conference--Forum for Discovery ------------------------------------------------------------------------ BOARD OF REGENTS FOR Dissecting the 05/13/2018 $200,000.00 UNIVERSITY OF NEBRASKA Decision: Documenting and Discussing the Clinical Practice Patterns of Hematologic Oncology ------------------------------------------------------------------------ REGENTS OF THE 24th Annual San 05/13/2018 $10,000.00 UNIVERSITY OF Diego Heart CALIFORNIA Failure Symposium ------------------------------------------------------------------------ CLEVELAND CLINIC Intensive Review 05/15/2018 $10,000.00 EDUCATIONAL FOUNDATION of Cardiology ------------------------------------------------------------------------ GORDON RESEARCH 2018 Heterocyclic 05/15/2018 $2,000.00 CONFERENCE Gordon Research Conference ------------------------------------------------------------------------ CARDIOVASCULAR RESEARCH 30th Annual 05/16/2018 $40,000.00 FOUNDATION Transcatheter Cardiovascular Therapeutics ------------------------------------------------------------------------ AMERICAN ACADEMY OF 2018 Family 05/16/2018 $19,000.00 FAMILY PHYSICIANS Medicine Experience Interactive Lecture titled Acute Coronary Syndrome ------------------------------------------------------------------------ HUNTSVILLE HOSPITAL RSS Breast Cancer 05/16/2018 $2,000.00 FOUNDATION Conference ------------------------------------------------------------------------ SOCIETY OF 2018 WCIO 05/20/2018 $15,000.00 INTERVENTIONAL ONCOLOGY (SIO) ------------------------------------------------------------------------ UNIVERSITY OF University of 05/20/2018 $24,300.00 WASHINGTON SCHOOL OF Washington Topics MEDICINE in Allergy and Immunology Teaching Series ------------------------------------------------------------------------ THE GOG FOUNDATION 10th Semi Annual 05/21/2018 $20,000.00 Meeting of NRG Oncology (formerly NCI cooperatives groups, GOG, NSABP, RTOG) ------------------------------------------------------------------------ NORTHWESTERN UNIVERSITY 20th Annual Lynn 05/21/2018 $15,000.00 Sage Breast Cancer Symposium ------------------------------------------------------------------------ AMERICAN ASSOCIATION Molecular Biology 05/22/2018 $15,000.00 FOR CANCER RESEARCH in Clinical Oncology Workshop ------------------------------------------------------------------------ UNIVERSITY OF COLORADO Precision Medicine 05/23/2018 $20,000.00 in Autoimmunity ------------------------------------------------------------------------ MEDICAL LEARNING PeerView Live at 05/23/2018 $313,240.00 INSTITUTE, INC. CAP18: Molecular Testing for EGFR Mutations in the Context of a Changing Treatment Landscape, Evolving Testing Options, and New Guidelines (150205165) ------------------------------------------------------------------------ THE UNIVERSITY OF TEXAS 2018 Lung Cancer 05/23/2018 $15,000.00 SOUTHWESTERN MEDICAL SPORE Workshop CENTER ------------------------------------------------------------------------ AMERICAN COLLEGE OF ACEP18, ACEP 05/23/2018 $20,000.00 EMERGENCY PHYSICIANS National Scientific Assembly--Cardiov ascular Track ------------------------------------------------------------------------ HOSPITAL QUALITY Advances in the 05/23/2018 $222,127.50 FOUNDATION, LLC Management of Acute and Chronic Hyperkalemia: An Update for Emergency Medicine, Hospitalists and Healthcare Providers (MD, PA and CRNP) ------------------------------------------------------------------------ GORDON RESEARCH 2018 Cardiac 05/23/2018 $5,000.00 CONFERENCE Regulatory Mechanisms Gordon Research Conference ------------------------------------------------------------------------ CONQUER CANCER 2018 ASCO Annual 05/24/2018 $30,000.00 FOUNDATION OF THE Meeting Head and AMERICAN SOCIETY OF Neck Cancer Track CLINICAL ONCOLOGY ------------------------------------------------------------------------ CONQUER CANCER 2018 ASCO Pre- 05/24/2018 $10,000.00 FOUNDATION OF THE Annual Meeting AMERICAN SOCIETY OF Seminar: New CLINICAL ONCOLOGY Drugs in Oncology ------------------------------------------------------------------------ FEDERATION OF CLINICAL 18th Annual 05/24/2018 $10,000.00 IMMUNOLOGY SOCIETIES Meeting of the Federation of Clinical Immunology Societies ------------------------------------------------------------------------ NATIONAL COMPREHENSIVE 2018-2019 Monthly 05/24/2018 $75,000.00 CANCER NETWORK Oncology Tumor Boards: A Multidisciplinary Approach to Individualized Patient Care ------------------------------------------------------------------------ WINTHROP UNIVERSITY 3rd Annual NYU 05/24/2018 $3,000.00 HOSPITAL Winthrop Breast Health Symposium ------------------------------------------------------------------------ CONQUER CANCER 2018 ASCO Annual 05/27/2018 $25,000.00 FOUNDATION OF THE Meeting Lung AMERICAN SOCIETY OF Cancer Track CLINICAL ONCOLOGY ------------------------------------------------------------------------ MISSOURI ACADEMY OF Updates in 05/30/2018 $3,000.00 PHYSICIANS ASSISTANTS Treating Chronic Obstructive Pulmonary Disorder ------------------------------------------------------------------------ MEDICAL LEARNING Emergency Medicine 06/03/2018 $568,470.00 INSTITUTE, INC. and Immuno- Oncology Intersect: Recognizing and Managing Immune- Related Adverse Effects in the Emergency Department (150205075) ------------------------------------------------------------------------ NATIONAL COMPREHENSIVE NCCN 2018 Oncology 06/03/2018 $40,000.00 CANCER NETWORK, INC. Case Manager and Medical Director Program ------------------------------------------------------------------------ AMERICAN SOCIETY FOR ASTRO 2018 60th 06/03/2018 $50,000.00 RADIATION ONCOLOGY Annual Meeting ------------------------------------------------------------------------ UNIVERSITY OF 2018 Pittsburgh 06/04/2018 $10,000.00 PITTSBURGH International Lung Conference-- Pulmonary Medicine: Basic Biology and Novel Therapies ------------------------------------------------------------------------ AEGEAN CONFERENCES, 2nd International 06/05/2018 $5,000.00 INC. Conference on Tissue Repair, Regeneration, and Fibrosis ------------------------------------------------------------------------ SYNAPTIV, INC. Atlanta Lung 06/05/2018 $20,000.00 Cancer Symposium 2018 ------------------------------------------------------------------------ SOCIETY FOR NSCLC Treatment in 06/05/2018 $38,885.00 TRANSLATIONAL ONCOLOGY the Era of Precision Medicine: Case- Based Insights from ASCO 2018 ------------------------------------------------------------------------ MEDICAL LEARNING Traveling Master 06/06/2018 $390,030.00 INSTITUTE, INC. Class for Emergency Medicine Specialists: Urgent Care of Patients Receiving Cancer Immunotherapy: Recognition and Management of Immune-Mediated Adverse Reactions in the ED ------------------------------------------------------------------------ PRESIDENT AND FELLOWS 33rd Annual 06/06/2018 $15,000.00 OF HARVARD COLLEGE Critical Issues In Tumor Microenvironment: Angiogenesis, Metastasis and Immunology ------------------------------------------------------------------------ KERN ASPEN LIPID Metabolic 06/06/2018 $10,000.00 CONFERENCE Regulation of Immunity, Cardiometabolic Diseases and Cancer: New Theraepeutic Approaches ------------------------------------------------------------------------ SOCIETY OF TOXICOLOGIC STP 37th Annual 06/06/2018 $3,000.00 PATHOLOGY Symposium: KEEPING IT RENAL ------------------------------------------------------------------------ WEILL CORNELL MEDICAL 2nd Annual 06/10/2018 $15,000.00 COLLEGE International Conference Immunotherapy Radiotherapy Combinations ------------------------------------------------------------------------ AMERICAN COLLEGE OF 2018 COPD Learning 06/10/2018 $5,000.00 CHEST PHYSICIANS Track ------------------------------------------------------------------------ AMERICAN COLLEGE OF 2018 06/10/2018 $27,000.00 CHEST PHYSICIANS Interdisciplinary Program--Lung Cancer: 2018 Update in Staging and Management ------------------------------------------------------------------------ AMERICAN COLLEGE OF Breathing New Air 06/10/2018 $20,400.00 OSTEOPATHIC INTERNISTS into the Treatment of COPD and Asthma ------------------------------------------------------------------------ THE RECTOR AND VISITORS PREP2018 Symposium 06/10/2018 $5,000.00 OF THE UNIVERSITY OF VIRGINIA ------------------------------------------------------------------------ SOCIETY FOR NEURO- 3rd CNS Anticancer 06/11/2018 $15,000.00 ONCOLOGY Drug Discovery and Development Conference ------------------------------------------------------------------------ ANNENBERG CENTER FOR 2018 JADPRO Live: 06/12/2018 $50,000.00 HEALTH SCIENCES AT The Annual APSHO EISENHOWER Meeting--Sequenci ng Therapies in Indolent Lymphomas ------------------------------------------------------------------------ AMERICAN COLLEGE OF ACOI 2018 Annual 06/12/2018 $33,782.00 OSTEOPATHIC INTERNISTS Convention and Scientific Sessions: Addressing Unmet Needs in Type 2 ------------------------------------------------------------------------ UNIVERSITY OF Moving Toward A 06/13/2018 $59,912.00 CINCINNATI New Standard of Care: Checkpoint Inhibitors in Advanced Urothelial Cancer ------------------------------------------------------------------------ AMERICAN ASSOCIATION OF Reducing 06/13/2018 $178,188.13 DIABETES EDUCATORS Cardiovascular Risk in T2DM with SGLT2 Inhibitors and GLP1-Receptor Antagonists: Translating Evidence into Patient Outcomes ------------------------------------------------------------------------ SOCIETY FOR NEURO- 23rd Annual 06/13/2018 $75,000.00 ONCOLOGY Scientific Meeting of the Society for Neuro- Oncology ------------------------------------------------------------------------ AMERICAN COLLEGE OF 2018 Lung Cancer 06/13/2018 $70,000.00 CHEST PHYSICIANS Learning Track ------------------------------------------------------------------------ UNIVERSITY OF Request for 2018 06/14/2018 $5,000.00 CALIFORNIA BERKELEY Funding for the FOUNDATION Forum for Collaborative Research's Program on HBV ------------------------------------------------------------------------ JOHNS HOPKINS OncologyConsults.c 06/15/2018 $89,885.00 UNIVERSITY SCHOOL OF om Improving MEDICINE Outcomes in Stage III NSCLC The Emerging Role of Immunotherapy in Curbing Disease Progression ------------------------------------------------------------------------ SOCIETY FOR Advances in Cancer 06/17/2018 $500,000.00 IMMUNOTHERAPY OF ImmunotherapyT CANCER 2018-19 Educational Program Series ------------------------------------------------------------------------ METABOLIC ENDOCRINE Medications' Class 06/19/2018 $100,000.00 EDUCATION FOUNDATION Effects in DM and CVD--All you need to know- and never asked. ------------------------------------------------------------------------ MEDICAL LEARNING PeerView Live at 06/21/2018 $262,040.00 INSTITUTE, INC. ASCP 2018: Navigating the Complexities of Molecular Testing for EGFR Mutations to Guide Selection of EGFR-Targeted Therapy for Patients With Lung Cancer (150205135) ------------------------------------------------------------------------ NORTHWESTERN UNIVERSITY Lurie Cancer 06/21/2018 $10,000.00 Center Multidisciplinary Head and Neck Symposium ------------------------------------------------------------------------ CHARLOTTE AHEC 30th Annual Fall 06/25/2018 $5,000.00 Foliage Cancer Conference ------------------------------------------------------------------------ KEYSTONE SYMPOSIA ON Integrated 06/25/2018 $6,000.00 MOLECULAR AND CELLULAR Pathways of BIOLOGY Disease in NASH and NAFLD ------------------------------------------------------------------------ AMERICAN SOCIETY OF ASN Kidney Week 06/25/2018 $20,000.00 NEPHROLOGY Educational Session Support ------------------------------------------------------------------------ GORDON RESEARCH DNA Topoisomerases 06/25/2018 $10,000.00 CONFERENCE in Biology and Medicine ------------------------------------------------------------------------ INDUSTRY NETWORKING BioHealth Capital 06/25/2018 $10,000.00 GROUP Region Workforce Community Engagement ------------------------------------------------------------------------ AMERICAN COLLEGE OF Unraveling the 07/01/2018 $33,782.00 OSTEOPATHIC INTERNISTS Effects of Antihyperglycemic Agents on Cardiovascular Risk ------------------------------------------------------------------------ MEDICAL LEARNING PeerView Live at 07/02/2018 $262,040.00 INSTITUTE, INC. ASCP 2018: Advances and Challenges in Refining the Use of Cancer Immunotherapies Through Biomarker Testing (150205136) ------------------------------------------------------------------------ ENDOCRINE FELLOWS Fifth Annual 07/02/2018 $250,000.00 FOUNDATION Research Forum ------------------------------------------------------------------------ SOCIETY FOR SITC 2018 Workshop 07/02/2018 $100,000.00 IMMUNOTHERAPY OF on Nutrition, CANCER Metabolism and the Microbiome in Cancer Therapy ------------------------------------------------------------------------ AMERICAN SOCIETY OF The Role of 07/02/2018 $167,500.00 NEPHROLOGY Hypoxia-Inducible Factors and Inflammation in the Anemia of Kidney Disease ------------------------------------------------------------------------ AMERICAN ACADEMY OF Managing 07/04/2018 $160,000.00 PHYSICIAN ASSISTANTS Cardiovascular Risk Factors in Patients with Type 2 Diabetes: Emerging Concepts ------------------------------------------------------------------------ AMERICAN SOCIETY OF ASH Meeting on 07/04/2018 $60,000.00 HEMATOLOGY Hematologic Malignancies ------------------------------------------------------------------------ AMERICAN HEART Scientific 07/05/2018 $20,000.00 ASSOCIATION Sessions 2018 Dedicated Programming on Acute Coronary Syndrome ------------------------------------------------------------------------ BREATHE CALIFORNIA OF 2018 BREATHE 07/08/2018 $3,000.00 LOS ANGELES COUNTY California of Los Angeles County 10th Annual COPD Conference ------------------------------------------------------------------------ SOCIETY FOR INDUSTRIAL SIMB Annual 07/08/2018 $3,000.00 MICROBIOLOGY AND Meeting BIOTECHNOLOGY ------------------------------------------------------------------------ JOSLIN DIABETES CENTER, 2018 AANHPI 07/08/2018 $5,000.00 INC. Diabetes Coalition Conference The Future of Population Diabetes Research and Advocacy: Asian American Native Hawaiian Pacific Islanders ------------------------------------------------------------------------ ACS DIVISION OF Division of 07/09/2018 $2,500.00 MEDICINAL CHEMISTRY Medicinal Chemistry Program 256th ACS national meeting ------------------------------------------------------------------------ GORDON RESEARCH Gordon Research 07/10/2018 $10,000.00 CONFERENCES, INC. Conference Tissue Niches and Resident Stem Cells in Adult Epithelia ------------------------------------------------------------------------ NORTH AMERICAN Reducing 07/11/2018 $60,000.00 THROMBOSIS FORUM Cardiovascular Risk in Patients with Diabetes: A Comprehensive Yet Concise Patient Focused Action Plan ------------------------------------------------------------------------ AMERICAN ACADEMY OF 36th Annual Aspen 07/11/2018 $3,000.00 ALLERGY ASTHMA AND Allergy IMMUNOLOGY Conference ------------------------------------------------------------------------ SOCIETY FOR SITC 33rd Annual 07/16/2018 $400,000.00 IMMUNOTHERAPY OF Meeting CANCER ------------------------------------------------------------------------ SOCIETY FOR SITC Cancer 07/16/2018 $67,500.00 IMMUNOTHERAPY OF Immunotherapy CANCER Sparkathon 2018-- Emerging Leaders Igniting Innovation ------------------------------------------------------------------------ AMERICAN COLLEGE OF Respiratory 07/16/2018 $35,000.00 CHEST PHYSICIANS Syncytial Virus (RSV) Education Program ------------------------------------------------------------------------ BINAYTARA FOUNDATION 6th International 07/16/2018 $5,000.00 Conference on Advances in Hematology and Oncology ------------------------------------------------------------------------ SOCIETY FOR MUCOSAL Mucosal Immunology 07/16/2018 $10,000.00 IMMUNOLOGY Course and Symposium ------------------------------------------------------------------------ BAYLOR COLLEGE OF Breast Cancer 07/17/2018 $3,000.00 MEDICINE Research and Education program ------------------------------------------------------------------------ AMERICAN ASSOCIATION AACR Conference on 07/17/2018 $25,000.00 FOR CANCER RESEARCH The Science of Cancer Health Disparities ------------------------------------------------------------------------ MEDICAL LEARNING PeerView Live at 07/18/2018 $164,230.00 INSTITUTE, INC. CAP18: The Central Role of Biomarker Testing in Piecing Together the Immuno-Oncology Puzzle in the Era of Precision Medicine (150205123) ------------------------------------------------------------------------ PENNSYLVANIA STATE PeerView inClinic, 07/18/2018 $32,330.00 UNIVERSITY Building Innovative Treatment Options for Patients with B-cell Malignancies: Practical Insights on Clinical Evidence and Integration Strategies 150205182 ------------------------------------------------------------------------ ANNENBERG CENTER FOR 2018 JADPRO Live: 07/19/2018 $50,000.00 HEALTH SCIENCES AT The Annual APSHO EISENHOWER Meeting--Sequenci ng of Treatments for Patients with Ovarian Cancer ------------------------------------------------------------------------ AMERICAN SOCIETY OF ASH Scholar Awards 07/20/2018 $100,000.00 HEMATOLOGY ------------------------------------------------------------------------ AMERICAN SOCIETY OF 60th ASH Annual 07/20/2018 $150,000.00 HEMATOLOGY Meeting ------------------------------------------------------------------------ AMERICAN ASSOCIATION AACR Cancer Health 07/22/2018 $25,000.00 FOR CANCER RESEARCH Disparities Think Tank ------------------------------------------------------------------------ ASSOCIATION OF Association of 07/23/2018 $10,000.00 PHYSICIAN ASSISTANTS Physician IN ONCOLOGY Assistants in Oncology 21st Annual Conference ------------------------------------------------------------------------ ANNENBERG CENTER FOR 2018 JADPRO Live: 07/24/2018 $50,000.00 HEALTH SCIENCES AT The Annual APSHO EISENHOWER Meeting--Manageme nt of Side Effects for Patients with Multi-Modality Therapy in Thoracic Oncology ------------------------------------------------------------------------ AMERICAN SOCIETY OF Kidney Health 07/24/2018 $30,000.00 NEPHROLOGY Initiative ------------------------------------------------------------------------ GORDON RESEARCH 2018 Gordon 07/26/2018 $2,500.00 CONFERENCES Research Conference and Seminar on Cell Death ------------------------------------------------------------------------ JOHNS HOPKINS Fifth Annual 07/29/2018 $10,000.00 UNIVERSITY SCHOOL OF Metastatic Breast MEDICINE Cancer Conference ------------------------------------------------------------------------ AMERICAN ASSOCIATION AACR Translational 07/31/2018 $25,000.00 FOR CANCER RESEARCH Cancer Research for Basic Scientists Workshop ------------------------------------------------------------------------ BOARD OF REGENTS FOR Virtual 08/01/2018 $75,000.00 UNIVERSITY OF NEBRASKA Challenging Case Clinic: B-Cell Lymphomas ------------------------------------------------------------------------ MASSACHUSETTS GENERAL Gene Panel 08/01/2018 $100,000.00 HOSPITAL Testing: Decision Aid ------------------------------------------------------------------------ LUNG CANCER ALLIANCE Florida and 08/01/2018 $199,200.00 Georgia Lung Cancer Screening Demonstration Project ------------------------------------------------------------------------ YALE SCHOOL OF MEDICINE Severe Asthma 2018 08/01/2018 $15,000.00 Advances in Pathogenesis and Treatment ------------------------------------------------------------------------ UTAH CHAPTER OF THE Rockies Chapter 08/02/2018 $3,000.00 AMERICAN COLLEGE OF Meeting CARDIOLOGY ------------------------------------------------------------------------ SOCIETY FOR Immune Escape: 08/02/2018 $25,000.00 IMMUNOTHERAPY OF Current CANCER Understanding of Mechanisms and Advances in Therapeutics Approaches ------------------------------------------------------------------------ LUNG CANCER ALLIANCE Florida and 08/02/2018 $147,972.00 Georgia Lung Cancer Screening Demonstration Project ------------------------------------------------------------------------ NATIONAL JEWISH HEALTH 23rd Annual 08/02/2018 $5,000.00 Regional Allied Health Conference: Current Perspectives in Asthma, Allergy, and Pulmonary Practice ------------------------------------------------------------------------ AMERICAN ASSOCIATION FDA-AACR Workshop 08/02/2018 $25,000.00 FOR CANCER RESEARCH on Non-clinical Models for Safety Assessment of Immunooncology Products ------------------------------------------------------------------------ NATIONAL ASSOCIATION OF Novel Treatment 08/06/2018 $35,000.00 MANAGED CARE Advances and PHYSICIANS, INC. Approaches in the Management of Advanced Breast Cancer: Expert Strategies for Individualized Treatment ------------------------------------------------------------------------ NATIONAL ASSOCIATION OF New Frontiers in 08/06/2018 $45,000.00 MANAGED CARE the Management of PHYSICIANS, INC. Ovarian Cancer: Exploring the Role of PARP Inhibitors in the Evolving Treatment Paradigm ------------------------------------------------------------------------ SOCIETY FOR 2018 SITC Primer 08/07/2018 $50,000.00 IMMUNOTHERAPY OF on Tumor CANCER Immunology and Cancer ImmunotherapyT ------------------------------------------------------------------------ SOCIETY FOR SITC 2018 Grant 08/07/2018 $10,000.00 IMMUNOTHERAPY OF Writing Workshop: CANCER Grant Writing: From Start to Finish, and Then Starting Again ------------------------------------------------------------------------ AMERICAS HEALTH The Diagnosis and 08/07/2018 $85,240.00 FOUNDATION Treatment of Hereditary Breast and Ovarian Cancer Syndrome in Brazil ------------------------------------------------------------------------ ADMINISTRATORS OF THE 18th Annual SSCI 08/10/2018 $55,000.00 TULANE EDUCATION FUND Nephrology Young Investigators Forum ------------------------------------------------------------------------ NATIONAL KIDNEY Joint Analyses of 08/10/2018 $105,895.00 FOUNDATION GFR slope and Change in Albuminuria by AstraZeneca and the CKDEPI Collaboration ------------------------------------------------------------------------ ANNENBERG CENTER FOR JADPRO Live 2018: 08/12/2018 $25,000.00 HEALTH SCIENCES AT New Drug Updates EISENHOWER ------------------------------------------------------------------------ UNIVERSITY OF FLORIDA Vascular Biology 08/12/2018 $7,500.00 Working Group Global Chapter Meeting ------------------------------------------------------------------------ NATIONAL COMPREHENSIVE Optimizing Small 08/12/2018 $50,000.00 CANCER NETWORK, INC. Molecule Inhibitor Therapy for Relapsed/ Refractory B-cell Lymphomas ------------------------------------------------------------------------ NATIONAL ASSOCIATION OF Improving Clinical 08/12/2018 $35,000.00 MANAGED CARE and Economic PHYSICIANS, INC. Outcomes with Emerging Therapies in the Management of Chronic Lymphocytic Leukemia (CLL) ------------------------------------------------------------------------ NATIONAL ASSOCIATION OF Optimizing 08/13/2018 $35,000.00 MANAGED CARE Treatment PHYSICIANS, INC. Strategies in the Management of Advanced Non- Small Cell Lung Cancer (NSCLC): Individualized Therapy for Improved Patient Outcomes ------------------------------------------------------------------------ NATIONAL COMPREHENSIVE NCCN 13th Annual 08/13/2018 $75,000.00 CANCER NETWORK, INC. Congress: Hematologic MalignanciesTM ------------------------------------------------------------------------ AMERICAN PANCREATIC 49th Annual 08/13/2018 $25,000.00 ASSOCIATION, INC. Meeting of the American Pancreatic Association ------------------------------------------------------------------------ REGENTS OF THE 16th Annual 08/14/2018 $50,000.00 UNIVERSITY OF Nephrology Young CALIFORNIA Investigators Forum ------------------------------------------------------------------------ PENNSYLVANIA STATE PeerView 08/15/2018 $115,000.00 UNIVERSITY COLLEGE OF MasterClass: MEDICINE Innovative Therapy in B-Cell Malignancies: An Expert Tumor Board on Novel Agent Classes in CLL, FL, and MCL (150205208) ------------------------------------------------------------------------ ASSOCIATION OF Series of AUTM 08/15/2018 $25,287.50 UNIVERSITY TECHNOLOGY 2019 Annual MANAGERS INC. Meetings ------------------------------------------------------------------------ TRANSLATIONAL RESEARCH TRIO-US & UCLA 08/16/2018 $5,000.00 IN ONCOLOGY-US, INC. Annual Research Conference ------------------------------------------------------------------------ DANA-FARBER CANCER IWWM10--Internatio 08/17/2018 $100,000.00 INSTITUTE nal Workshop on Waldenstroms macroglobulinemia ------------------------------------------------------------------------ MEDICAL LEARNING Integrating BTK 08/20/2018 $245,090.00 INSTITUTE, INC. Inhibitors into the Management of B cell Malignancies: How is Evidence Driving Patient Care ------------------------------------------------------------------------ MEDICAL LEARNING CRI-AACR ISS-- 08/20/2018 $324,460.00 INSTITUTE, INC. Improving Patient Outcomes With Cancer Immunotherapies and Combinations Throughout the Continuum of Lung Cancer (150205201) ------------------------------------------------------------------------ AMERICAN NEPHROLOGY ANNA Fall Meeting 08/20/2018 $42,500.00 NURSES ASSOCIATION CE Symposium (ANNA) ------------------------------------------------------------------------ AMERICAN SOCIETY OF Risk and Treatment 08/20/2018 $125,000.00 NEPHROLOGY of Hyperkalemia ------------------------------------------------------------------------ AMERICAN ASSOCIATION AACR-AstraZeneca 08/20/2018 $276,000.00 FOR CANCER RESEARCH Lymphoma Research Fellowships ------------------------------------------------------------------------ SOCIETY FOR 2019 SITC- 08/20/2018 $120,000.00 IMMUNOTHERAPY OF AstraZeneca CANCER Immunotherapy in Lung Cancer Clinical Fellowship ------------------------------------------------------------------------ GBMC HEALTHCARE Advances in 08/21/2018 $2,000.00 Treatment and Management of Ovarian Cancer ------------------------------------------------------------------------ NATIONAL COMPREHENSIVE PARP Inhibitors in 08/21/2018 $240,000.00 CANCER NETWORK Breast Cancer: Expert Perspectives on Clinical Application and Genetic Testing ------------------------------------------------------------------------ UT HEALTH SCIENCE 41st Annual San 08/21/2018 $75,000.00 CENTER AT SAN ANTONIO Antonio Breast SCHOOL OF MEDICINE Cancer Symposium OFFICE OF CME ------------------------------------------------------------------------ MEDICAL LEARNING PeerView Live--The 08/22/2018 $269,660.00 INSTITUTE, INC. Evolving Role of Immunotherapy as a Component of Multi-Modal Therapy in Earlier Stages of Lung Cancer: Rationale, Current Evidence, Key Trials, and Implications for Multidisciplinary Care (150205392) ------------------------------------------------------------------------ TEMPLE UNIVERSITY LUNG Severe 08/26/2018 $65,000.00 CENTER- OF THE Uncontrolled COMMONWEALTH SYSTEM OF Asthma: HIGHER EDUCATION Definition, Management, and Advance Therapies ------------------------------------------------------------------------ OHIO CHAPTER OF THE 28th Annual 08/26/2018 $4,500.00 AMERICAN COLLEGE OF Meeting of the CARDIOLOGY Ohio Chapter of the American College of Cardiology ------------------------------------------------------------------------ PROSTATE CANCER 25th Annual 08/27/2018 $20,000.00 FOUNDATION Scientific Retreat ------------------------------------------------------------------------ AMERICAN UROLOGICAL Advancing the 08/27/2018 $25,000.00 ASSOCIATION EDUCATION Treatment of AND RESEARCH, INC. Genitourinary Cancer ------------------------------------------------------------------------ THE ICAHN SCHOOL OF The Lancet Women 08/30/2018 $50,000.00 MEDICINE AT MOUNT and SINAI Cardiovascular Disease Commission ------------------------------------------------------------------------ NATIONAL COMPREHENSIVE Behind the 08/30/2018 $25,000.00 CANCER NETWORK Guidelines: Insights into the Standard of Care in Oncology 2019 ------------------------------------------------------------------------ NATIONAL COMPREHENSIVE Behind the 08/30/2018 $25,000.00 CANCER NETWORK Guidelines: Insights into the Standard of Care in Oncology 2019 ------------------------------------------------------------------------ THE BOARD OF TRUSTREES Stanford Review of 09/05/2018 $5,000.00 OF THE LELAND STANFORD the 60th Annual JUNIOR UNIVERSITY ON American Society BEHALF OF ITS SCHOOL of Hematology OF MEDICINE Meeting 2019 ------------------------------------------------------------------------ INTERNATIONAL CYTOKINE 6th Annual Meeting 09/11/2018 $20,000.00 AND INTERFERON SOCIETY of the INC. International Cytokine and Interferon Society ------------------------------------------------------------------------ CEDARS-SINAI 7th Annual New 09/11/2018 $10,000.00 Therapeutics in Oncology: The Road to Personalized Medicine ------------------------------------------------------------------------ MERCY HEALTH FOUNDATION 2019 Tri-State ASH 09/11/2018 $5,000.00 Update ------------------------------------------------------------------------ DUKE UNIVERSITY Duke Stanford CEC 09/18/2018 $20,000.00 Summit: Scientific, Regulatory and Operational Best Practices ------------------------------------------------------------------------ KENTUCKY ACADEMY OF Breast Cancer-- 09/18/2018 $3,000.00 PHYSICIAN ASSISTANTS Diagnosis and Patient Treatment Options ------------------------------------------------------------------------ THE UNIVERSITY OF TEXAS 13th Update on the 09/20/2018 $5,000.00 MD ANDERSON CANCER Management of CENTER Genitourinary Malignancies ------------------------------------------------------------------------ NATIONAL COMPREHENSIVE NCCN 2019 Congress 09/20/2018 $50,000.00 CANCER NETWORK, INC. SeriesTM: Breast Cancer with Updates from the 2018 San Antonio Breast Cancer Symposium ------------------------------------------------------------------------ AMERICAN SOCIETY OF Hematology 2018: 09/21/2018 $100,000.00 HEMATOLOGY the ASH Education Program Book ------------------------------------------------------------------------ PENN STATE COLLEGE OF Consensus or 09/23/2018 $75,000.00 MEDICINE Controversy? Clinical Investigators Provide Perspectives on the Current and Future Management of Patients with Prostate Cancer-- An ISS Held as a Premium Ancillary Educational Event During the 2019 Genitourinary Cancers Symposium ------------------------------------------------------------------------ HARTFORD HOSPITAL 34th Annual 09/23/2018 $5,000.00 Cardiovascular Symposium presented by Hartford HealthCare ------------------------------------------------------------------------ JOHN HOPKINS UNIVERSITY Novel Therapeutic 09/24/2018 $5,000.00 Approaches to Allergic Diseases ------------------------------------------------------------------------ INTERNATIONAL SOCIETY Advances in 09/24/2018 $2,500.00 FOR MAGNETIC RESONANCE Multiscale Cancer IN MEDICINE Detection: From Micro to Macro ------------------------------------------------------------------------ PARENTERAL DRUG PDA Universe of 10/01/2018 $24,000.00 ASSOCIATION (PDA) Pre-filled Syringes and Injection Devices ------------------------------------------------------------------------ KEYSTONE SYMPOSIA ON 2019 Keystone 10/01/2018 $25,000.00 MOLECULAR AND CELLULAR Symposia BIOLOGY Directors' Fund ------------------------------------------------------------------------ MEMORIAL SLOAN State-of-the-Art 10/01/2018 $5,000.00 KETTERING CANCER Gynecologic CENTER Surgery and Ovarian Cancer Management Conference 2018 ------------------------------------------------------------------------ UNIVERSITY OF TEXAS Official Best of 10/02/2018 $60,000.00 HEALTH SCIENCE CENTER San Antonio AT SAN ANTONIO Breast Cancer Symposium ------------------------------------------------------------------------ AMERICAN ASSOCIATION AACR-AstraZeneca 10/03/2018 $276,000.00 FOR CANCER RESEARCH Immuno-Oncology Research Fellowships ------------------------------------------------------------------------ MEDCHI, THE MARYLAND OPTIMAL DURATION 10/8/2018 $387,213.13 STATE MEDICAL SOCIETY OF ANTIPLATELET THERAPY AFTER PCI: The Case for Longerterm Dual Antiplatelet Therapy in Patients with History of MI ------------------------------------------------------------------------ AMERICAN COLLEGE OF Symposium 4: 10/08/2018 $5,000.00 TOXICOLOGY Update on RNA Therapies: Challenges and Opportunities, American College of Toxicology 39th Annual Meeting ------------------------------------------------------------------------ PEPTIDE THERAPEUTICS 13th Annual 10/08/2018 $15,000.00 FOUNDATION Peptide Therapeutics Symposium ------------------------------------------------------------------------ UNIVERSITY OF NEBRASKA 7th International 10/09/2018 $5,000.00 MEDICAL CENTER Conference on Gram-Positive Pathogens ------------------------------------------------------------------------ JOHNS HOPKINS 2019 Atlanta 10/09/2018 $10,000.00 UNIVERSITY SCHOOL OF Breast Cancer MEDICINE OFFICE OF Symposium CONTINUING MEDICAL EDUCATION ------------------------------------------------------------------------ LYMPHOMA RESEARCH LRF Postdoctoral 10/10/2018 $105,000.00 FOUNDATION Fellowship ------------------------------------------------------------------------ THE GOG FOUNDATION INC. 11th Semi Annual 10/10/2018 $20,000.00 Meeting of NRG Oncology (formerly GOG, NSABP, RTOG) cooperative groups ------------------------------------------------------------------------ THE UNIVERSITY OF Chicago Lung 10/10/2018 $10,000.00 CHICAGO Cancer Updates 2018 ------------------------------------------------------------------------ AMERICAN ASSOCIATION OF The Liver Meeting 10/11/2018 $15,000.00 THE STUDY OF LIVER 2018 Park Benches DISEASES Support ------------------------------------------------------------------------ NATIONAL ANIMAL The Continued 10/14/2018 $2,000.00 INTEREST ALLIANCE Importance of Animal Research ------------------------------------------------------------------------ AMERICAN ASSOCIATION AACR-AstraZeneca 10/17/2018 $276,000.00 FOR CANCER RESEARCH Lung Cancer Research Fellowships (Driver Mutations) ------------------------------------------------------------------------ THE COOPER HEALTH Contemporary 10/22/2018 $2,500.00 SYSTEM Practices in Cardiology ------------------------------------------------------------------------ AMERICAN SOCIETY OF 2019 Highlights of 10/22/2018 $100,000.00 HEMATOLOGY ASH in North America ------------------------------------------------------------------------ EMORY UNIVERSITY SCHOOL 3rd National 10/24/2018 $5,000.00 OF MEDICINE Congress on the Prevention of Diabetes and Its Complications ------------------------------------------------------------------------ MEMORIAL SLOAN 2018 Annual Cancer 10/24/2018 $5,000.00 KETTERING CANCER Treatment-Related CENTER Adverse Events Symposium ------------------------------------------------------------------------ ECOG RESEARCH AND 2018 ECOG-ACRIN 10/24/2018 $5,000.00 EDUCATION FOUNDATION, Fall Group INC. Meeting ------------------------------------------------------------------------ AMERICAN ASSOCIATION AACR Special 10/28/2018 $25,000.00 FOR CANCER RESEARCH Conference on Tumor Immunology and Immunotherapy ------------------------------------------------------------------------ INTERNATIONAL Best of 19th World 10/28/2018 $20,000.00 ASSOCIATION FOR THE Conference on STUDY OF LUNG CANCER Lung Cancer (WCLC) ------------------------------------------------------------------------ WASHINGTON UNIVERSITY 45th Annual 10/29/2018 $3,000.00 Washington University Kilo Diabetes Symposium ------------------------------------------------------------------------ VIRGINIA BIOTECHNOLOGY Medimmune 11/01/2018 $25,000.00 ASSOCIATION Chariman's Circle Membership ------------------------------------------------------------------------ METABOLIC ENDOCRINE 16th Annual World 11/01/2018 $100,000.00 EDUCATION FOUNDATION congress on Insulin Resistance Diabetes and Cardiovascular Disease (WCIRDC) ------------------------------------------------------------------------ MEDICAL LEARNING PeerView Live--ISS 11/01/2018 $286,060.00 INSTITUTE, INC. at the Thoracic Cancers Symposium, "The Present and Future of Immunotherapy as a Key Component of the Treatment Arsenal for Locally Advanced and Earlier Stages of Lung Cancer: State of the Science, Practicalities, and Implications for Mult ------------------------------------------------------------------------ METABOLIC ENDOCRINE CHF, the Next 11/01/2018 $150,705.00 EDUCATION FOUNDATION Frontier in Diabetes: Do SGLT2 Inhibitors Have a Role in Management and Prevention? ------------------------------------------------------------------------ NATIONAL COMPREHENSIVE ASCO and NCCN 2019 11/01/2018 $60,000.00 CANCER NETWORK, INC. ISS CCO: PARP Inhibitors in Breast Cancer: Expert Perspectives on Clinical Application and Genetic Testing ------------------------------------------------------------------------ BOARD OF REGENTS OF THE Grand Rounds 11/01/2018 $250,000.00 UNIVERSITY OF NEBRASKA series Bioascend: 2019 Ovarian Community Grand Rounds: Incorporating Recently Approved Targeted Agents, Emerging Combinations, and Genetic Testing for the Optimal Management of Patients with Ovarian Cancer ------------------------------------------------------------------------ NATIONAL ASSOCIATION OF Webinars: PARP 11/01/2018 $150,000.00 MANAGED CARE Inhibition and PHYSICIANS, INC. its Evolving Use in the Treatment of Cancers: What Managed Care Needs to Know for Improved Clinical and Economic Outcomes ------------------------------------------------------------------------ JOHNS HOPKINS FastForward Silver 11/05/2018 $25,000.00 UNIVERSITY Sponsorship ------------------------------------------------------------------------ ASSOCIATION FOR WOMEN Innovation and 11/05/2018 $25,000.00 IN SCIENCE Inclusion Summit ------------------------------------------------------------------------ FOUNDATION FOR THE 2018 Biomarkers 11/05/2018 $10,000.00 NATIONAL INSTITUTES OF Consortium Cancer HEALTH Steering Committee Annual Scientific Symposium ------------------------------------------------------------------------ MEDICAL LEARNING PeerView Oncology-- 11/06/2018 $324,340.00 INSTITUTE, INC. ISS at ASCO-SITC, Seminars in Immuno-Oncology, ``III, II, I: Addressing Unmet Needs in Earlier Stages of NSCLC With Immunotherapy'' (150205292) ------------------------------------------------------------------------ MEDICAL LEARNING ISS at 2019 11/06/2018 $286,060.00 INSTITUTE, INC. Multidisciplinary Thoracic Cancers Symposium- Refining Current Practice and Exploring New Frontiers in EGFR- Mutant NSCLC (150205322) ------------------------------------------------------------------------ AMERICAN COLLEGE OF Comparative 11/06/2018 $2,000.00 VETERINARY Pathologists in PATHOLOGISTS Translational Medicine reception at the 2018 ACVP/ASVCP Concurrent Annual Meeting ------------------------------------------------------------------------ AMERICAN ASSOCATION OF AAPS PharmSci 360 11/06/2018 $50,000.00 PHARMACEUTICAL SCIENTISTS ------------------------------------------------------------------------ MAYO CLINIC ARIZONA Mayo Clinic Cancer 11/07/2018 $5,000.00 Center Thoracic Oncology Update State of the Art Evaluation and Management of Thoracic Cancers ------------------------------------------------------------------------ SOCIETY FOR Case-based Forum: 11/07/2018 $20,000.00 CARDIOVASCULAR Individualizing ANGIOGRAPHY AND Antithrombotic INTERVENTIONS Therapies for PCI FOUNDATION Patients ------------------------------------------------------------------------ UT HEALTH SAN ANTONIO 2019 Practical 11/07/2018 $5,000.00 Application of New Agents in Oncology ------------------------------------------------------------------------ AMERICAN SOCIETY FOR 2018 Best of ASTRO 11/07/2018 $10,000.00 RADIATION ONCOLOGY ------------------------------------------------------------------------ PERSONALIZED MEDICINE 14th Annual 11/11/2018 $25,000.00 COALITION Personalized Medicine Conference ------------------------------------------------------------------------ ACLAM FOUNDATION 2018 ACLAM Grants 11/11/2018 $4,000.00 ------------------------------------------------------------------------ ICAHN SCHOOL OF LIVE Conference: 11/11/2018 $5,000.00 MEDICINE AT MOUNT 3rd International SINAI Prostate Cancer and Urologic Oncology Symposium ------------------------------------------------------------------------ AMERICAN SOCIETY FOR 2019 11/11/2018 $50,000.00 RADIATION ONCOLOGY Multidisciplinary Thoracic Cancers Symposium ------------------------------------------------------------------------ CENTER FOR MEDICAL Core Outcomes in 11/11/2018 $75,000.00 TECHNOLOGY POLICY Non-Alcoholic Steatohepatitis ------------------------------------------------------------------------ THE UNIVERSITY OF TEXAS Medical Oncology 11/11/2018 $10,000.00 MD ANDERSON CANCER and Hematology CENTER 2019: Multidisciplinary Approaches that Improve Coordination of Care ------------------------------------------------------------------------ NATIONAL COMPREHENSIVE NCCN 2019 Nursing 11/11/2018 $30,000.00 CANCER NETWORK, INC. Program: Advancing Oncology NursingT at the NCCN Annual Conference ------------------------------------------------------------------------ NORTH AMERICAN 3R'S Virtual Education 11/11/2018 $4,000.00 COLLABORATIVE Community (VEC) Support ------------------------------------------------------------------------ COLLEGIUM 32nd Biennial 11/12/2018 $40,000.00 INTERNATIONALE Symposium of the ALLERGOLOGICUM Collegium Internationale Allergologicum ------------------------------------------------------------------------ PENN STATE COLLEGE OF ISS at AACR BTK 11/12/2018 $370,330.00 MEDICINE Inhibition as an Anti-Cancer Strategy: Exploring a Model for Modern Targeted Therapy in Hematologic Malignancies and Beyond (150205409) ------------------------------------------------------------------------ CLEVELAND CLINIC Cleveland Clinic 11/12/2018 $5,000.00 EDUCATIONAL FOUNDATION Florida's 2nd Annual San Antonio Breast Cancer Symposium SABCS Official Review Course ------------------------------------------------------------------------ MAYO CLINIC Mayo Clinic 11/12/2018 $15,000.00 JACKSONVILLE Advances in Breast Cancer Management 2019 ------------------------------------------------------------------------ LEUKEMIA RESEARCH Hollis Brownstein 11/13/2018 $100,000.00 FOUNDATION INC. Research Grants Program ------------------------------------------------------------------------ MEDICAL LEARNING ISS at ONS- Taking 11/13/2018 $317,050.00 INSTITUTE, INC. Aim at B-Cell Malignancies with BTK Inhibitors: Hematology/ Oncology Nurse Perspectives and Insights on Clinical Care (150205361) ------------------------------------------------------------------------ MEDSTAR HEALTH, INC. Lung Cancer 2018: 11/15/2018 $5,000.00 Progress and Future Directions ------------------------------------------------------------------------ NATIONAL KIDNEY Research 11/18/2018 $28,800.00 FOUNDATION initiative to extend the analytical work related to evaluation of clinical endpoints suitable for early phase trials in CKD using the CKD- Epidemiology Consortium (CKD- EPI) ------------------------------------------------------------------------ BOARD OF REGENTS OF THE 2019 Lymphoma 11/20/2018 $7,500.00 UNIVERSITY OF NEBRASKA Study Group Hematology Highlights A Post ASH Review ------------------------------------------------------------------------ SCRIPPS HEALTH 39th Annual 11/20/2018 $25,000.00 Clinical Hematology and Oncology Conference ------------------------------------------------------------------------ AMERICAN ACADEMY OF Pharmacists' Role 11/25/2018 $49,800.00 CME, INC. in the Comprehensive Care of Acute Coronary Syndrome ------------------------------------------------------------------------ PREVENTIVE Connecting Heart 11/26/2018 $40,000.00 CARDIOVASCULAR NURSES Disease and ASSOCIATION Diabetes-HCP Live and On-Demand Education ------------------------------------------------------------------------ UHS PROFESSIONAL Women's Health 11/26/2018 $5,000.00 EDUCATION PROGRAMS 2019 INC. (DBA VCU HEALTH CONTINUING MEDICAL EDUCATION) ------------------------------------------------------------------------ CARDIOVASCULAR RESEARCH 25th Annual 11/26/2018 $15,000.00 FOUNDATION Interventional Cardiology Fellows Course ------------------------------------------------------------------------ CEDARS-SINAI MEDICAL 13th Annual Women 11/28/2018 $5,000.00 CENTER and Ischemic Heart Disease Symposium ------------------------------------------------------------------------ SCRIPPS HEALTH Dr. Richard Schatz 11/28/2018 $5,000.00 Interventional Cardiology Summit ------------------------------------------------------------------------ KEYSTONE SYMPOSIA ON 2019 DNA 11/29/2018 $10,000.00 MOLECULAR AND CELLULAR Replication and BIOLOGY Genome Instability: From Mechanism to Disease A1 ------------------------------------------------------------------------ THE UNIVERSITY OF TEXAS 11th ANNUAL 11/29/2018 $50,000.00 MD ANDERSON CANCER HEMATOLOGIC CENTER MALIGNANCIES DEMYSTIFIED: A CRITICAL APPRAISAL OF DATA FROM 2018 ------------------------------------------------------------------------ MEDSTAR WASHINGTON Cardiovascular 11/29/2018 $25,000.00 HOSPITAL CENTER Research Technologies, (CRT) 2019 ------------------------------------------------------------------------ CONQUER CANCER 2019 Conquer 12/02/2018 $40,000.00 FOUNDATION OF THE Cancer Foundation AMERICAN SOCIETY OF of ASCO Merit CLINICAL ONCOLOGY Awards ------------------------------------------------------------------------ NORTHWELL HEALTH New York City-- 12/02/2018 $20,000.00 Debates in Interventional Cardiology ------------------------------------------------------------------------ AMERICAN COLLEGE OF New York 12/02/2018 $10,000.00 CARDIOLOGY FOUNDATION Cardiovascular Symposium ------------------------------------------------------------------------ INTERNATIONAL 11th Biennial 12/02/2018 $25,000.00 EOSINOPHIL SOCIETY, Symposium INC. ------------------------------------------------------------------------ JOHNS HOPKINS Grand Rounds 12/03/2018 $150,000.00 UNIVERSITY SCHOOL OF series MCM:15 MEDICINE visting faculty series: Novel Targeted Agents in the Management of Recurrent Advanced Ovarian Cancer ------------------------------------------------------------------------ CONQUER CANCER 2019 Conquer 12/03/2018 $500,000.00 FOUNDATION OF THE Cancer Foundation AMERICAN SOCIETY OF of ASCO Mission CLINICAL ONCOLOGY Endowment ------------------------------------------------------------------------ AMERICAN ASSOCIATION AACR-AstraZeneca 12/03/2018 $276,000.00 FOR CANCER RESEARCH Breast Cancer Research Fellowships ------------------------------------------------------------------------ AMERICAN ASSOCIATION AACR-AstraZeneca 12/03/2018 $276,000.00 FOR CANCER RESEARCH Ovarian Cancer Research Fellowships (DNA Damage Response) ------------------------------------------------------------------------ AMERICAN SOCIETY OF ASH Bridge Grant 12/03/2018 $150,000.00 HEMATOLOGY Program ------------------------------------------------------------------------ GORDON RESEARCH Gordon Research 12/03/2018 $4,000.00 CONFERENCE Conference: Biotherapeutics and Vaccines Development ------------------------------------------------------------------------ INDIANA UNIVERSITY Breast Cancer Year 12/03/2018 $5,000.00 in Review ------------------------------------------------------------------------ AMERICAN ASSOCIATION AACR Annual 12/03/2018 $225,000.00 FOR CANCER RESEARCH Meeting 2019 ------------------------------------------------------------------------ TEXAS HEART INSTITUTE 9th Annual Women's 12/03/2018 $3,000.00 Heart and Vascular Symposium: A New Era in Prevention, Diagnosis and Treatment ------------------------------------------------------------------------ AMERICAN COLLEGE OF 2018 Managing 12/03/2018 $150,000.00 CARDIOLOGY FOUNDATION Cardiovascular Risk in Diabetes Roundtable ------------------------------------------------------------------------ INTERNATIONAL IASLC 19th 12/03/2018 $100,000.00 ASSOCIATION FOR THE Targeted STUDY OF LUNG CANCER Therapies for Lung Cancer Meeting ------------------------------------------------------------------------ NORTH CAROLINA THORACIC North Carolina 12/04/2018 $14,500.00 SOCIETY Thoracic Society Annual Meeting ------------------------------------------------------------------------ CONQUER CANCER 2019 Conquer 12/05/2018 $287,500.00 FOUNDATION OF THE Cancer Foundation AMERICAN SOCIETY OF of ASCO Young CLINICAL ONCOLOGY Investigator Award (YIA) ------------------------------------------------------------------------ CONQUER CANCER 2019 Conquer 12/05/2018 $230,000.00 FOUNDATION OF THE Cancer Foundation AMERICAN SOCIETY OF of ASCO Career CLINICAL ONCOLOGY Development Award (CDA) ------------------------------------------------------------------------ FRIENDS OF CANCER 2019 Friends of 12/05/2018 $200,000.00 RESEARCH Cancer Research Programs ------------------------------------------------------------------------ COLEGIO DE MEDICOS Innovations in 12/06/2018 $10,000.00 CIRUJANOS DE PUERTO Medicine 2018 RICO ------------------------------------------------------------------------ SOCIETY FOR SITC's Cancer 12/06/2018 $150,000.00 IMMUNOTHERAPY OF Immunotherapy CANCER Winter School ------------------------------------------------------------------------ USF HEALTH PROFESSIONS 15th Annual 12/06/2018 $7,500.00 CONFERENCING Clinical CORPORATION Breakthroughs and Challenges in Hematologic Malignancies ------------------------------------------------------------------------ SOCIETY FOR SITC's Cancer 12/09/2018 $100,000.00 IMMUNOTHERAPY OF Immunotherapy CANCER Guidelines Project ------------------------------------------------------------------------ AMERICAN UROLOGICAL Next Frontiers in 12/09/2018 $10,000.00 ASSOCIATION Urology 2019: a Biennial AUA/JUA Symposium ------------------------------------------------------------------------ HOSPITAL QUALITY Update on NSTEMI 12/10/2018 $185,000.00 FOUNDATION Management for Hospitalists ------------------------------------------------------------------------ CARDIOVASCULAR RESEARCH DAPT Dilemmas: A 12/12/2018 $25,000.00 FOUNDATION Case-Based Roundtable Tutorial ------------------------------------------------------------------------ ST. DOMINIC-JACKSON Neuroscience 12/12/2018 $5,000.00 MEMORIAL HOSPITAL Cardiovascular Symposium ------------------------------------------------------------------------ HEART FAILURE SOCIETY 2019 Future 12/12/2018 $25,000.00 OF AMERICA INC. Leaders in Heart Failure Symposium ------------------------------------------------------------------------ CONQUER CANCER 2019 12/13/2018 $40,000.00 FOUNDATION OF THE Gastrointestinal AMERICAN SOCIETY OF (GI) Cancers CLINICAL ONCOLOGY Symposium: Multidisciplinary Treatment, Personalized Care, Optimal Outcomes ------------------------------------------------------------------------ UNIVERSITY OF NEBRASKA ONS 2019 ISS 12/13/2018 $150,000.00 MEDICAL CENTER Bioascend: Patient and Nurse Perspectives on the Use of PARP Inhibitors for Ovarian Cancer: Strategies for Maximizing Patient Outcomes ------------------------------------------------------------------------ THE UNIVERSITY OF TEXAS 2019 Oncologic 12/13/2018 $20,000.00 MD ANDERSON CANCER Emergency CENTER Medicine Conference ------------------------------------------------------------------------ DUKE UNIVERSITY 4th Annual Duke 12/13/2018 $3,000.00 Heart Center/DCRI Fellows' Presentation Skills Course ------------------------------------------------------------------------ FEDERATION OF AMERICAN Acute Kidney 12/16/2018 $5,000.00 SOCIETIES FOR Injury: from EXPERIMENTAL BIOLOGY beside to bench (and back again) ------------------------------------------------------------------------ CONQUER CANCER 2019 ASCO-SITC 12/16/2018 $70,000.00 FOUNDATION OF THE Clinical Immuno- AMERICAN SOCIETY OF Oncology CLINICAL ONCOLOGY Symposium ------------------------------------------------------------------------ PENNYSLVANIA SOCIETY 2018 Educational 12/16/2018 $2,000.00 FOR BIOMEDICAL Programming RESEARCH Support ------------------------------------------------------------------------ AMERICAN DIABETES Pathway to Stop 12/16/2018 $500,000.00 ASSOCIATION Diabetes ------------------------------------------------------------------------ MEDICAL LEARNING ISS at ASCO GI-- 12/17/2018 $37,500.00 INSTITUTE, INC. Breaking the Paradox: Expanding Options and New Questions in HCC Management (150205289) ------------------------------------------------------------------------ C DAVIS AND S THOMPSON Corporate 12/17/2018 $2,000.00 DVM FOUNDATION Membership ------------------------------------------------------------------------ MIDWINTER CONFERENCE OF 58th Midwinter 12/18/2018 $5,000.00 IMMUOLOGISTS Conference of Immunologists ------------------------------------------------------------------------ SOCIETY FOR SITC General 12/19/2018 $3,000.00 IMMUNOTHERAPY OF Society CANCER ------------------------------------------------------------------------ NATIONAL ACADEMY OF Roundtable in 12/20/2018 $4,000.00 SCIENCES Science and Welfare of Laboratory Animal Use ------------------------------------------------------------------------ MIT Koch Institute 12/23/2018 $5,000.00 2019 Immune Engineering Symposium ------------------------------------------------------------------------ NATIONAL KIDNEY The Role of the 01/03/2019 $100,000.00 FOUNDATION Kidney and SGLT2 in Glucose Homeostasis and Kidney Disease: A Scientific Workshop Sponsored by the National Kidney Foundation ------------------------------------------------------------------------ AMERICAN ACADEMY OF AAAAI Foundation 01/03/2019 $150,000.00 ALLERGY, ASTHMA AND 2019 Lectureship IMMUNOLOGY FOUNDATION, Series INC. ------------------------------------------------------------------------ NATIONAL JEWISH HEALTH 15th Annual 01/03/2019 $299,856.00 Respiratory Disease Young Investigators' Forum ------------------------------------------------------------------------ MEDICAL LEARNING ONS 2019 ISS 01/07/2019 $250,000.00 INSTITUTE INC. Peerview:, ``Realizing the Promise of PARP Inhibitors in Solid Tumor Therapy Guiding Oncology Nurses on the Advances and Challenges'' (150205359) ------------------------------------------------------------------------ AMERICAN SOCIETY OF Kidney Health 01/14/2019 $30,000.00 NEPHROLOGY Initiative ------------------------------------------------------------------------ MELANOMA RESEARCH Melanoma Research 01/14/2019 $10,000.00 ALLIANCE Alliance 11th Annual Scientific Retreat ------------------------------------------------------------------------ METABOLIC ENDOCRINE 3rd Annual Heart 01/15/2019 $100,000.00 EDUCATION FOUNDATION in Diabetes (HiD) ------------------------------------------------------------------------ COLD SPRING HARBOR Integrated control 01/16/2019 $10,000.00 LABORATORY of feeding and energy balance by hypothalamic and hindbrain circuits ------------------------------------------------------------------------ NEW YORK UNIVERSITY XXIV Conference on 01/16/2019 $5,000.00 the Chemistry of the Organic Solid State ------------------------------------------------------------------------ NATIONAL JEWISH HEALTH 41st Annual 01/22/2019 $10,000.00 National Jewish Health Pulmonary and Allergy Update ------------------------------------------------------------------------ MEDICAL LEARNING ISS at AATS 2019 01/22/2019 $302,760.00 INSTITUTE INC. Broadening Horizons:The Expanding Role of Immunotherapy in Locally Advanced and Earlier Stages of Lung Cancer (150205422) ------------------------------------------------------------------------ MEDICAL LEARNING CAP Chapter 01/24/2019 $414,050.00 INSTITUTE, INC. Meetings: Molecular Testing for EGFR Mutations in the Context of a Changing Treatment Landscape, Evolving Testing Options, and New Guidelines What Do Pathologists Need to Know and Do? (150205307) ------------------------------------------------------------------------ LUNGEVITY FOUNDATION LUNGevity 02/03/2019 $10,000.00 Foundation Nursing and Nurse Navigator Roundtable ------------------------------------------------------------------------ REGENTS OF UC SAN DIEGO 2nd Annual Multi- 02/04/2019 $25,000.00 Disciplinary Head and Neck Cancer Conference- Maximizing Speech and Swallowing Outcomes in Patients Undergoing Radiation Therapy: We're in This Together ------------------------------------------------------------------------ UNIVERSITY OF KANSAS 2018 San Antonio 02/06/2019 $5,000.00 MEDICAL CENTER Breast Cancer Symposium Review ------------------------------------------------------------------------ NATIONAL ASSOCIATION OF Individualizing 02/06/2019 $22,500.00 MANAGED CARE Treatment in the PHYSICIANS, INC. Management of Advanced Breast Cancer: How Novel Therapies Are Changing the Treatment Paradigm ------------------------------------------------------------------------ NATIONAL ASSOCIATION OF Integrating New 02/06/2019 $22,500.00 MANAGED CARE and Emerging PHYSICIANS, INC. Targeted Therapies into the Treatment Paradigm in Ovarian Cancer: Expert Strategies for Improved Patient Outcomes ------------------------------------------------------------------------ FEDERATION OF AMERICAN Mitochondrial 02/07/2019 $10,000.00 SOCIETIES FOR Biogenesis and EXPERIMENTAL BIOLOGY Dynamics in Health and Disease ------------------------------------------------------------------------ NATIONAL JEWISH HEALTH Impact of 02/07/2019 $64,925.00 Educational Program on the Career Development of Physician Scientists; Outcomes from 14 years of the Annual Respiratory Disease Young Investigators' Forum--An Article for Publication ------------------------------------------------------------------------ NYU SCHOOL OF MEDICINE Asthma Airways and 02/10/2019 $20,000.00 the Environment ------------------------------------------------------------------------ MEDSTAR HEALTH Mid-Atlantic 02/10/2019 $50,000.00 Nephrology Young Investigators Forum ------------------------------------------------------------------------ SOCIETY OF GYNECOLOGIC SGO 2019 Annual 02/10/2019 $62,500.00 ONCOLOGY Meeting on Women's Cancer ------------------------------------------------------------------------ COLUMBIA UNIVERSITY Heart Disease and 02/11/2019 $7,500.00 DEPARTMENT OF SURGERY Women ------------------------------------------------------------------------ AMERICAN DIABETES 66th Advanced 02/11/2019 $40,000.00 ASSOCIATION Postgraduate Course ------------------------------------------------------------------------ NATIONAL KIDNEY Hypoxia-Inducible 02/11/2019 $100,000.00 FOUNDATION Factor Stabilization as an Emerging Therapy for CKD Related Anemia A Scientific Workshop Sponsored by the National Kidney Foundation ------------------------------------------------------------------------ NATIONAL COMPREHENSIVE 2019-2020 Monthly 02/13/2019 $25,000.00 CANCER NETWORK, INC. Oncology Tumor Boards: A Multidisciplinary Approach to Individualized Patient Care ------------------------------------------------------------------------ NATIONAL COMPREHENSIVE 2019-2020 Monthly 02/13/2019 $25,000.00 CANCER NETWORK, INC. Oncology Tumor Boards: A Multidisciplinary Approach to Individualized Patient Care ------------------------------------------------------------------------ THE SOCIETY OF SURGICAL SSO 2019 Annual 02/14/2019 $5,000.00 ONCOLOGY Cancer Symposium ------------------------------------------------------------------------ ONCOLOGY NURSING ONS Evidence-Based 02/17/2019 $293,500.00 SOCIETY Practice Improvement Project: Constipation ------------------------------------------------------------------------ THE UNIVERSITY OF 16th Annual 02/17/2019 $50,000.00 CHICAGO International Ultmann Chicago Lymphoma Symposium ------------------------------------------------------------------------ HOUSTON METHODIST Heart of a Woman 02/17/2019 $3,000.00 HOSPITAL ------------------------------------------------------------------------ HEMATOLOGY/ONCOLOGY HOPA 15th Annual 02/18/2019 $35,000.00 PHARMACY ASSOCIATION Conference ------------------------------------------------------------------------ BAYLOR SCOTT AND WHITE 8th Annual 02/18/2019 $10,000.00 HEALTH Symposium on Current Strategies in the Treatment of Multiple Myeloma, Leukemia, Hodgkin's Lymphoma and B- cell Non- Hodgkin's Lymphoma ------------------------------------------------------------------------ USF HEALTH PROFESSIONS CARDIOVASCULAR AND 02/18/2019 $247,330.00 CONFERENCING RENAL CORPORATION COMPLICATIONS IN T2DM: Roles of Physician Assistants and Nurse Practitioners in Patient Management ------------------------------------------------------------------------ NATIONAL ASSOCIATION OF New Horizons in 02/18/2019 $35,000.00 MANAGED CARE the Treatment and PHYSICIANS, INC. Management of B- Cell Non-Hodgkin Lymphoma: A Closer Look at the Role of Emerging Targeted Therapies ------------------------------------------------------------------------ ONCOLOGY NURSING ONS 44th Annual 02/18/2019 $50,000.00 SOCIETY Congress and Regional Workshops ------------------------------------------------------------------------ MEDICAL LEARNING PeerView inVision: 02/19/2019 $122,250.00 INSTITUTE INC. ``New Frontiers in Managing Heart Failure: Are SGLT2 Inhibitors the Next Leap Forward in Optimizing Patient Care?'' (150205455) ------------------------------------------------------------------------ NATIONAL COMPREHENSIVE NCCN 2019 Annual 02/19/2019 $75,000.00 CANCER NETWORK, INC. Conference: Improving the Quality, Effectiveness, and Efficiency of Cancer CareTM ------------------------------------------------------------------------ ACS DIVISION OF 257th ACS National 02/19/2019 $2,000.00 MEDICINAL CHEMISTRY Meeting ------------------------------------------------------------------------ ASSOCIATION FOR TARC Targeting DNA 02/19/2019 $125,000.00 MOLECULAR PATHOLOGY Repair Pathways: Current and Future Implications of PARP Inhibitors ------------------------------------------------------------------------ COLUMBIA UNIVERSITY Pancreas Symposium 02/20/2019 $3,000.00 DEPARTMENT OF SURGERY 2019: Current Controversies in Benign and Malignant Pancreatic Disease ------------------------------------------------------------------------ CONQUER CANCER 2019 ASCO Annual 02/20/2019 $30,000.00 FOUNDATION OF THE Meeting Breast AMERICAN SOCIETY OF Cancer Track CLINICAL ONCOLOGY ------------------------------------------------------------------------ ST. JOSEPH REGIONAL Annual 02/21/2019 $1,000.00 HEALTH NETWORK Cardiovascular Symposium ------------------------------------------------------------------------ ANNENBERG CENTER FOR Master Class for 02/21/2019 $25,000.00 HEALTH SCIENCES AT Oncologists 2019-- EISENHOWER Women's Cancer Track ------------------------------------------------------------------------ ANNENBERG CENTER FOR Master Class for 02/21/2019 $25,000.00 HEALTH SCIENCES AT Oncologists 2019-- EISENHOWER Hematologic Malignancies Track ------------------------------------------------------------------------ AMERICAN COLLEGE OF Achieving 02/24/2019 $1,500.00 PHYSICIANS; PUERTO Excellence in RICO CHAPTER Patient Care American College of Physician Annual Meeting and Internal Medicine Update and Board Review ------------------------------------------------------------------------ MEDICAL LEARNING PeerView Video in 02/25/2019 $95,975.00 INSTITUTE INC. Exchange Navigating Clinical Challenges to Maximize the Benefits and Minimize the Risks of Cancer Immunotherapies (150204478) ------------------------------------------------------------------------ COLUMBIA UNIVERSITY Breast Cancer 02/26/2019 $2,000.00 DEPARTMENT OF SURGERY Management 2019 ------------------------------------------------------------------------ HOLY CROSS HOSPITAL Updates in the 02/28/2019 $2,000.00 INC. Treatment of Common Cancers: Lung, Gastrointestinal, GYN, and Breast ------------------------------------------------------------------------ HOLY CROSS HOSPITAL Updates in the 02/28/2019 $2,000.00 INC. Treatment of Common Cancers: Lung, Gastrointestinal, GYN, and Breast ------------------------------------------------------------------------ NATIONAL KIDNEY Chronic 03/01/2019 $257,085.00 FOUNDATION Hyperkalemia Management and Outcomes in CKD ------------------------------------------------------------------------ AMERICAN ACADEMY OF Crucial 03/03/2019 $99,990.00 CME, INC. Conversations in Nephrology: PHD Inhibition as an Emerging Approach to Treating CKD Anemia ------------------------------------------------------------------------ UNIVERSITY OF ROCHESTER 20th Annual 03/03/2019 $6,500.00 Diabetes Conference: Current Treatments for Diabetes Complications ------------------------------------------------------------------------ CLEVELAND CLINIC Advanced 03/03/2019 $10,000.00 EDUCATIONAL FOUNDATION Diagnostic Bronchoscopy Workshop ------------------------------------------------------------------------ PREVENTIVE Cardiovascular 03/03/2019 $50,000.00 CARDIOVASCULAR NURSES Risk Reduction: ASSOCIATION 25th Cardiovascular Nursing Symposium Opening Session ------------------------------------------------------------------------ PENN STATE COLLEGE OF An Update on SGLT2 03/03/2019 $142,430.00 MEDICINE Inhibition for the Prevention and Treatment of Kidney Disease in Patients with Type 2 Diabetes (150205286) ------------------------------------------------------------------------ REGENTS OF THE Making the 03/03/2019 $200,000.00 UNIVERSITY OF Connection: A CALIFORNIA, SAN DIEGO Comprehensive Strategy on the Modern Management of Type 1 and Type 2 Diabetes 2019 ------------------------------------------------------------------------ ANNENBERG CENTER FOR From Inquiry to 03/03/2019 $50,000.00 HEALTH SCIENCES AT Investigation to EISENHOWER Insight (I3): Clinical Clarity in Non-Small Cell Lung Cancer--The 2019 JADPRO Lung Cancer Conference ------------------------------------------------------------------------ NATIONAL ASSOCIATION OF Advances in the 03/03/2019 $30,000.00 MANAGED CARE Management of PHYSICIANS, INC. Acute Coronary Syndrome (ACS): Updated Guideline Recommendations for Dual Antiplatelet Therapy ------------------------------------------------------------------------ EASTERN VIRGINIA Turning the Tide 03/03/2019 $5,000.00 MEDICAL SCHOOL on Diabetes 2019 ------------------------------------------------------------------------ AMERICAN ACADEMY OF Foundations of 03/04/2019 $200,000.00 ALLERGY ASTHMA AND Asthma Management IMMUNOLOGY ------------------------------------------------------------------------ KEYSTONE SYMPOSIA ON 2019 Cancer 03/04/2019 $5,000.00 MOLECULAR AND CELLULAR Immunotherapy: BIOLOGY Mechanistic Insights to Improve Clinical Benefit ------------------------------------------------------------------------ METABOLIC ENDOCRINE The Primary 03/04/2019 $154,110.00 EDUCATION FOUNDATION Prevention of CHF and CKD in Diabetes Satellite Symposium ------------------------------------------------------------------------ THE CHEST FOUNDATION 2019 CHEST 03/04/2019 $35,000.00 Foundation Research Award in Severe Asthma ------------------------------------------------------------------------ MEDICAL LEARNING PeerView Live at 03/04/2019 $90,000.00 INSTITUTE INC. USCAP 2019, Clinical Advances in Cancer Immunotherapies, Biomarkers, and Testing: Implications for Pathologists at the Forefront of the Emerging Precision Oncology Era (150205529) ------------------------------------------------------------------------ AMERICAN NEPHROLOGY The CKD Patient 03/05/2019 $61,500.00 NURSES ASSOCIATION with (ANNA) Hyperkalemia: Nephrology Nurses Evidence Based Care ------------------------------------------------------------------------ NATIONAL ASSOCIATION OF Improving Clinical 03/05/2019 $35,000.00 MANAGED CARE and Economic PHYSICIANS, INC. Outcomes with Personalized Treatment in the Management of Advanced Non- Small Cell Lung Cancer (NSCLC) ------------------------------------------------------------------------ DUKE UNIVERSITY The Southeastern 03/06/2019 $2,500.00 Fellows Research Skills and Training Workshop ------------------------------------------------------------------------ NATIONAL COMPREHENSIVE NCCN 2019 Oncology 03/06/2019 $10,000.00 CANCER NETWORK, INC. Fellows Program: New Horizons in Quality Cancer CareT at the NCCN Annual Conference ------------------------------------------------------------------------ UNIVERSITY OF Allergy Fellowship 03/06/2019 $40,000.00 WASHINGTON SCHOOL OF MEDICINE ------------------------------------------------------------------------ DREXEL MEDICINE Updates In Women's 03/06/2019 $2,000.00 Health 2109 ------------------------------------------------------------------------ MEDICAL LEARNING Addressing Unmet 03/06/2019 $122,250.00 INSTITUTE INC. Needs in Managing Anemia in Chronic Kidney Disease: A Closer Look at the Clinical Potential of HIF- PH Inhibitors (150205556) ------------------------------------------------------------------------ SIDNEY KIMMEL MEDICAL 7th Annual Lung 03/06/2019 $2,500.00 COLLEGE AT THOMAS Cancer Symposium JEFFERSON UNIVERSITY ------------------------------------------------------------------------ MEDICAL LEARNING ASCO 2019 peer 03/10/2019 $30,000.00 INSTITUTE INC. view Stories from the Pancreatic Cancer CaseBook: Taking the Road to Improved Outcomes with Modern Therapeutic Concepts and Innovative Treatments (150205416) ------------------------------------------------------------------------ AMERICAN COLLEGE OF GKCAS 2019 Annual 03/10/2019 $3,000.00 ALLERGY, ASTHMA AND Meeting IMMUNOLOGY ------------------------------------------------------------------------ REGENTS OF THE 13th International 03/10/2019 $25,000.00 UNIVERSITY OF Congress on CALIFORNIA Systemic Lupus Erythematosus (LUPUS 2019) ------------------------------------------------------------------------ NATIONAL COMPREHENSIVE Support for NCCN 03/11/2019 $60,000.00 CANCER NETWORK, INC. Distribution of the NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelinesr) for Management of Immunotherapy- Related Toxicities Pocket Guides ------------------------------------------------------------------------ AMERICAN UROLOGICAL Bladder Cancer in 03/11/2019 $15,000.00 ASSOCIATION Women: Identifying Research Needs to Improve Diagnosis and Treatment A Johns Hopkins Greenberg Bladder Cancer Institute/ American Urological Association Translational Research Collaboration ------------------------------------------------------------------------ GORDON RESEARCH 2019 Multidrug 03/11/2019 $2,500.00 CONFERENCES Efflux Systems Gordon Research Conference ------------------------------------------------------------------------ NATIONAL KIDNEY 14th Annual Young 03/12/2019 $50,000.00 FOUNDATION Investigator's Forum ------------------------------------------------------------------------ AMERICAN COLLEGE OF Lung Cancer 03/12/2019 $25,000.00 CHEST PHYSICIANS Screening Decision Counselor and Navigator Training ------------------------------------------------------------------------ SOCIETY OF SIR Annual 03/13/2019 $12,500.00 INTERVENTIONAL Scientific RADIOLOGY Meeting ------------------------------------------------------------------------ ECOG RESEARCH AND ECOG-ACRIN Spring 03/13/2019 $5,000.00 EDUCATION FOUNDATION, 2019 Group INC. Meeting ------------------------------------------------------------------------ MEDSTAR HEALTH, INC. Kidney and Bladder 03/14/2019 $10,000.00 Cancers 2019 ------------------------------------------------------------------------ AMERICAN COLLEGE OF ACC Annual 03/14/2019 $50,000.00 CARDIOLOGY FOUNDATION Scientific Session ------------------------------------------------------------------------ SAINT FRANCIS HOSPITAL 55th Annual Robert 03/14/2019 $5,000.00 AND MEDICAL CENTER M. Jeresaty, MD Cardiovascular Symposium ------------------------------------------------------------------------ CARDIOVASCULAR RESEARCH A New Beat: 03/14/2019 $25,000.00 FOUNDATION Improving Cardiovascular Care in Women and Minorities ------------------------------------------------------------------------ GORDON RESEARCH Therapeutically 03/14/2019 $2,500.00 CONFENCE Targeted Small Molecules and Enabling Technologies in Drug Discovery ------------------------------------------------------------------------ NATIONAL COMPREHENSIVE Support for NCCN 03/14/2019 $25,000.00 CANCER NETWORK Distribution of the NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelinesr) for Breast Cancer Pocket Guides ------------------------------------------------------------------------ NORTHWELL HEALTH 1st Annual Heart 03/17/2019 $15,000.00 of Prevention Symposium: Updates on Cardiovascular Disease Prevention With a Focus on Women's Heart Health ------------------------------------------------------------------------ AMERICAN THORACIC ATS 2019 Fellows 03/17/2019 $10,000.00 SOCIETY INC. Track Symposium ------------------------------------------------------------------------ SOCIETY FOR SITC's PD-L1 03/17/2019 $35,000.00 IMMUNOTHERAPY OF Resistance CANCER Definition Project ------------------------------------------------------------------------ CITY OF HOPE 8th Annual 03/17/2019 $10,000.00 Clinical Cancer Genetics and Genomics Conference; From Exceptionalism to Exceptional Care: Mainstreaming Genomic Medicine in Clinical Practice ------------------------------------------------------------------------ FEDERATION OF AMERICAN 2019 FASEB SRC on 03/18/2019 $5,000.00 SOCIETIES FOR Intracellular RNA EXPERIMENTAL BIOLOGY localization and local translation ------------------------------------------------------------------------ FOUNDATION FOR HEART 23rd Annual Heart 03/18/2019 $10,000.00 FAILURE EDUCATION, Failure-An Update INC. on Therapy ------------------------------------------------------------------------ PURDUE UNIVERSITY Type 2 Diabetes 03/19/2019 $75,000.00 Mellitus and Heart Failure: Screening, Diagnosis, and Management ------------------------------------------------------------------------ ASTHMA AND ALLERGY ``Wheezin, Sneezin 03/19/2019 $10,000.00 FOUNDATION OF AMERICA-- and Itchin in ALASKA CHAPTER Alaska'' ------------------------------------------------------------------------ AMERICAN RADIUM SOCIETY 101st Annual 03/19/2019 $25,000.00 Meeting ------------------------------------------------------------------------ NATIONAL KIDNEY Anemia in Chronic 03/19/2019 $257,085.00 FOUNDATION Kidney Disease: Arming Clinicians with Meaningful Solutions ------------------------------------------------------------------------ AMERICAN UROLOGICAL The Evolving Role 03/19/2019 $25,000.00 ASSOCIATION EDUCATION of the Urologist AND RESEARCH, INC. in Advanced Castration Dependent Prostate Cancer: a Guidelines and Case-based Discussion ------------------------------------------------------------------------ NATIONAL COMPREHENSIVE Emerging Issues in 03/20/2019 $25,000.00 CANCER NETWORK, INC. Oncology--Ensurin g Access to, and Delivery of, Innovative Therapies and Patient Centered Care in Oncology ------------------------------------------------------------------------ ACS DIVISION OF 257th ACS National 03/20/2019 $5,000.00 BIOCHEMICAL TECHNOLOGY Meeting and Exposition (BIOT Division) ------------------------------------------------------------------------ Worksheet: Grants 2014 to Mar 20 2019 Appendix B -------------------------------------------------------------------------------------------------------------------------------------------------------- Product Q114 Q214 Q314 Q414 Q115 Q215 Q315 Q415 Q116 Q216 Q316 Q416 Q117 Q217 Q317 Q417 Q118 Q218 Q318 Q418 -------------------------------------------------------------------------------------------------------------------------------------------------------- FARXIGA X X X X X X X X -------------------------------------------------------------------------------------------------------------------------------------------------------- ONGLYZA X X X X X X X X X X X X X X X X -------------------------------------------------------------------------------------------------------------------------------------------------------- KOMBIGLYZE X X X X X X X X X X X X X -------------------------------------------------------------------------------------------------------------------------------------------------------- SYMBICORT X X X X X X X X X X X X -------------------------------------------------------------------------------------------------------------------------------------------------------- PULMICORT X X X X X X X X FLEXHALER -------------------------------------------------------------------------------------------------------------------------------------------------------- NEXIUM OS X X X X X X X X X X X X X X X X X X X X -------------------------------------------------------------------------------------------------------------------------------------------------------- NEXIUM XSULE X X X X X X X X X X X X X X X X X -------------------------------------------------------------------------------------------------------------------------------------------------------- CRESTOR X X X X X X X X X X X X X X X X X X X X -------------------------------------------------------------------------------------------------------------------------------------------------------- BYETTA X X X X X X X X X X X X X X X X -------------------------------------------------------------------------------------------------------------------------------------------------------- BYDUREON X X X X -------------------------------------------------------------------------------------------------------------------------------------------------------- SYMLIN X X X X X X X X X X X X X X X X X X X X -------------------------------------------------------------------------------------------------------------------------------------------------------- TUDORZA X X X X -------------------------------------------------------------------------------------------------------------------------------------------------------- X URA Capped at AMP Appendix C ------------------------------------------------------------------------ Product MPD Plan Effective Dates ------------------------------------------------------------------------ Abarca 1/1/18-12/31/19 ------------------------------------------------- Envision 1/1/18-12/31/18 ------------------------------------------------- Byetta Express Scripts 4/1/18-12/31/19 ------------------------------------------------- Health Delegates 1/1/18-12/31/18 ------------------------------------------------- MedImpact 1/1/19-12/31/19 ------------------------------------------------- SIS 1/1/18-12/31/19 ------------------------------------------------------------------------ Abarca 1/1/16-12/31/16 ------------------------------------------------- Blue Shield of CA 7/1/15-12/31/16; 5/2/16- 12/31/16 ------------------------------------------------- Emblem Health 1/1/15-12/31/15; 1/1/16- 12/31/16 ------------------------------------------------- Envision 1/1/17-12/31/17 ------------------------------------------------- Express Scripts 5/2/16-12/31/19 ------------------------------------------------- Florida Health 1/1/14-12/31/16 ------------------------------------------------- Health Alliance Medical 1/1/15-12/31/16 Plan ------------------------------------------------- Health Partners Plans 1/1/15-12/31/16 ------------------------------------------------- Healthspring 4/1/15-12/31/15 ------------------------------------------------- Highmark 7/1/14-12/31/16 ------------------------------------------------- Humana 1/1/15-12/31/16; 5/1/16- 7/30/16; 8/1/2016-P12/ 31/16 ------------------------------------------------- Crestor IHA 1/1/15-12/31/16 ------------------------------------------------- MedImpact 1/1/15-5/1/16 ------------------------------------------------- Navitus 1/1/15-12/31/16 ------------------------------------------------- OptumRx 7/1/16-12/31/17 ------------------------------------------------- Perform Rx 10/1/15-12/31/16 ------------------------------------------------- Pharm. Tech 1/1/15-12/31/16 ------------------------------------------------- Prime Therapeutics 5/2/16-12/31/16 ------------------------------------------------- SelectHealth 1/1/15-12/31/16 ------------------------------------------------- SilverScript 7/1/14-12/31/16 ------------------------------------------------- SIS 1/1/15-12/31/16 ------------------------------------------------- Ventegra 1/1/15-12/31/16 ------------------------------------------------- WellCare 1/1/15-12/31/16 ------------------------------------------------------------------------ Envision 1/1/17-12/31/17; 1/1/18- 12/31/18 ------------------------------------------------- Express Scripts 1/1/16-12/31/19 ------------------------------------------------- Harvard Pilgrim 1/1/14-12/31/14 ------------------------------------------------- Health Alliance Medical 1/1/14-12/31/14 Plan ------------------------------------------------- Healthspring 4/1/15-12/31/15 ------------------------------------------------- Highmark 7/1/14-12/31/16 ------------------------------------------------- Nexium Humana 1/1/14-12/31/14; 1/1/15- 12/31/16 ------------------------------------------------- Navitus 1/1/14-1/31/14; 1/1/15- 12/31/16 ------------------------------------------------- Optum Rx 1/1/14-12/31/18 ------------------------------------------------- Prime Therapeutics 1/1/14-12/31/14 ------------------------------------------------- Scott & White 1/1/14-12/31/14 ------------------------------------------------- SilverScript 7/1/14-12/31/16 ------------------------------------------------- WellCare 1/1/15-12/31/16 ------------------------------------------------------------------------ Abarca 1/1/16-12/31/16 ------------------------------------------------- Blue Shield of CA 1/1/15-12/31/16 ------------------------------------------------- Emblem Health 1/1/15-12/31/15; 1/1/16- 12/31/16 ------------------------------------------------- Envision 1/1/17-12/31/17; 1/1/18- 12/31/18 ------------------------------------------------- Health Partners Plans 1/1/15-12/31/16 ------------------------------------------------- Healthspring 4/1/15-12/31/15 ------------------------------------------------- Seroquel Highmark 7/1/14-12/31/16 ------------------------------------------------- Humana 1/1/15-12/31/16 ------------------------------------------------- IHA 1/1/15-12/31/16 ------------------------------------------------- Navitus 1/1/15-12/31/16; 1/1/17- 12/31/19 ------------------------------------------------- Perform Rx 10/1/15-12/31/16 ------------------------------------------------- Pharm. Tech 1/1/15-12/31/16; 1/1/18- 12/31/18 ------------------------------------------------- SelectHealth 1/1/17-12/31/18 ------------------------------------------------- SIS 1/1/15-12/31/16 ------------------------------------------------------------------------ Health Alliance Medical 1/1/15-12/31/16 Plan ------------------------------------------------- Seroquel XR SilverScript 7/1/14-12/31/16 ------------------------------------------------- Ventegra 1/1/15-12/31/16 ------------------------------------------------- WellCare 1/1/15-12/31/16 ------------------------------------------------------------------------ AstraZeneca Pharmaceuticals LP 1800 Concord Pike P.O. Box 15437 Wilmington DE 19850-5437 Tel 302-886-3000 www.astrazeneca-us.com March 7, 2019 The Honorable Charles E. Grassley Chairman Committee on Finance U.S. Senate Washington, DC 20510 The Honorable Ron Wyden Ranking Member Committee on Finance U.S. Senate Washington, DC 20510 Dear Chairman Grassley and Ranking Member Wyden: AstraZeneca's CEO Pascal Soriot appeared before your Committee on February 26, 2019 and answered a question from Senator Cortez Masto regarding whether AstraZeneca offers authorized generic versions of any of its products. At that time, Mr. Soriot indicated that AstraZeneca does not offer any authorized generics, however, following the hearing, Mr. Soriot was informed by AstraZeneca staff that an authorized generic is currently available in the U.S. This letter is intended to correct the record regarding that inadvertent oversight. AstraZeneca does, in fact, currently have one authorized generic in the U.S. market, and it was launched more than 3 years after the first generic of that product was introduced. Authorized generics are not a primary area of focus for AstraZeneca and are introduced on a selective basis. In limited circumstances, AstraZeneca has made an authorized generic available through a third-party distributor. Because patient prescription access and coverage may vary with respect to branded versus generic medicines, AstraZeneca believes it is important to keep branded options available for patients who continue to rely on them. We appreciate your invitation to discuss important issues of patient access and affordability with the Committee and the opportunity to supplement Mr. Soriot's testimony. We look forward to working with you as a constructive partner in addressing challenges in our health- care system. Sincerely, Christie Bloomquist Vice President, Corporate Affairs, North America ______ Prepared Statement of Jennifer Taubert, Executive Vice President, Worldwide Chairman, Janssen Pharmaceuticals, Johnson & Johnson Chairman Grassley, Ranking Member Wyden, and members of the committee, thank you for the opportunity to be here to discuss how we can ensure that Americans have affordable access to the best healthcare today and to the extraordinary medical breakthroughs of tomorrow. I am Jennifer Taubert, and I lead the Janssen Pharmaceutical Companies of Johnson & Johnson. At Janssen, we focus on discovering and developing transformational medicines that treat and cure some of the world's most challenging diseases, including blood cancers like multiple myeloma, chronic lymphocytic leukemia, and mantle cell lymphoma; prostate cancer; HIV; schizophrenia and other serious mental illnesses; cardiovascular diseases; rheumatoid arthritis; Crohn's Disease and other destructive gastrointestinal illnesses; and pulmonary hypertension, among others. Like many of you, I know what it's like when a loved one faces a serious disease. My own mother died of lung cancer in 1988, in her 40s. At the time, there was very little that could be done for my mom. I've committed my career to bringing families genuine, meaningful hope--hope for years of life, hope for the chance to be there for a daughter's wedding or the birth of a grandchild. commitment to innovation Last year Janssen invested $8.4 billion globally in research and development,\1\ making Janssen one of the world's top research and development (``R&D'') investors in any industry, anywhere in the world.\2\ In fact, our investment in R&D last year was 86 percent more than we spent on sales and marketing. This substantial investment has enabled us to research and develop more than 100 medicine candidates last year; and, over the past 5 years, we have introduced six innovative products in the U.S.\3\ The nine Breakthrough Therapy Designations we have received from the Food and Drug Administration (``FDA'') reflect the significance of the advances we are pursuing in areas of profound unmet medical need.\4\ --------------------------------------------------------------------------- \1\ Johnson & Johnson, FY18-Q4 Form 10-K for the Period Ending December 31, 2018 (filed February 20, 2019). \2\ PricewaterHouseCoopers. ``2018 Global Innovation 1000 Study.'' https://www.strategyand. pwc.com/innovation1000. \3\ U.S. Food and Drug Administration Center for Drug Evaluation and Research. ``NDA and BLA Approval Reports--New Molecular Entity (NME) Drug and New Biologic Approvals.'' https://wayback.archive- it.org/7993/20170404174205/https://www.fda.gov/Drugs/Develop mentApprovalProcess/HowDrugsareDevelopedandApproved/ DrugandBiologicApprovalReports/NDAandBLAApprovalReports/ucm373420.htm. \4\ U.S. Food and Drug Administration Center for Drug Evaluation and Research. ``CDER Breakthrough Therapy Designation Approvals.'' https://www.fda.gov/downloads/Drugs/DevelopmentApprovalProcess/ HowDrugsareDevelopedandApproved/DrugandBiologicApproval Reports/NDAandBLAApprovalReports/UCM481542.pdf. Our investment changes lives. It has helped turn HIV from a death sentence into a manageable disease. Today, people with HIV can have a near-normal life expectancy.\5\ And we are working on a vaccine with the potential to eliminate HIV altogether. Our biologic therapies have transformed the lives of patients with Inflammatory Bowel Disease by dramatically improving their quality of life. Our therapies have reduced major bowel surgeries for patients with Crohn's Disease by 82 percent and cut hospitalizations by 65 percent.\6\ In ulcerative colitis patients, our therapies have reduced the need for total colectomy by 41 percent.\7\ One of our earliest pharmaceutical innovations enabled people with serious mental illness to be treated at home and in their communities rather than in psychiatric institutions, and today our innovative first and only 4-time-a-year schizophrenia treatment is improving adherence and breaking the cycle of hospitalization so that people with schizophrenia can live their best lives.\8\ In the area of mental health, we are also investigating a new medicine for people suffering from treatment-resistant depression, which profoundly impacts these patients and their families and loved ones as well. Our first-in-class cancer medicines have helped patients with some of the most common and deadly types of cancer live longer, in some cases for many additional years.\9\, \10\ In multiple myeloma, one of our medicines has more than doubled the length of time patients live without return of their disease.\11\ We recently launched a new prostate cancer treatment that delays the spread of the disease by over an additional two years versus the prior standard of care.\12\, \13\ --------------------------------------------------------------------------- \5\ Trickey, Adam, Margaret T. May, Jorg-Janne Vehreschild, Niels Obel, M. John Gill, Heidi M. Crane, Christoph Boesecke et al. ``Survival of HIV-positive patients starting antiretroviral therapy between 1996 and 2013: a collaborative analysis of cohort studies.'' The Lancet HIV 4, no. 8 (2017): e349-e356. doi: 10.1016/S2352- 3018(17)30066-8. \6\ Lichtenstein, Gary R., Songkai Yan, Mohan Bala, Marion Blank, and Bruce E. Sands. ``Infliximab maintenance treatment reduces hospitalizations, surgeries, and procedures in fistulizing Crohn's disease.'' Gastroenterology 128, no. 4 (2005): 862-869. doi: 10.1053/ j.gastro.2005.01.048. \7\ Sandborn, William J., Paul Rutgeerts, Brian G. Feagan, Walter Reinisch, Allan Olson, Jewel Johanns, Jiandong Lu et al. ``Colectomy rate comparison after treatment of ulcerative colitis with placebo or infliximab.'' Gastroenterology 137, no. 4 (2009): 1250-1260. doi:10.1053/j.gastro.2009.06.061. \8\ INVEGA TRINZA U.S. Prescribing Information, January 2019. http://www.janssenlabels. com/package-insert/product-monograph/prescribing-information/ INVEGA+TRINZA-pi.pdf. \9\ IMBRUVICA U.S. Prescribing Information, January 2019. https:// www.imbruvica.com/docs/librariesprovider7/default-document-library/ prescribing-information.pdf. \10\ ZYTIGA U.S. Prescribing Information, April 2019. http:// www.janssenlabels.com/package-insert/product-monograph/prescribing- information/ZYTIGA-pi.pdf. \11\ Bahlis, Nizar, Meletios A. Dimopoulos, Darrell J. White, Lotfi Benboubker, Gordon Cook, Merav Leiba, P. Joy Ho et al. ``Three-Year Follow-up of the Phase 3 Pollux Study of Daratumumab Plus Lenalidomide and Dexamethasone (D-Rd) Versus Lenalidomide and Dexamethasone (Rd) Alone in Relapsed or Refractory Multiple Myeloma (RRMM).'' (2018): 1996-1996. doi: 10.1182/blood-2018-99-112697. \12\ DARZALEX U.S. Prescribing Information, June 2018. http:// www.janssenlabels.com/package-insert/product-monograph/prescribing- information/DARZALEX-pi.pdf. \13\ ERLEADA U.S. Prescribing Information, February 2018. http:// www.janssenlabels.com/package-insert/product-monograph/prescribing- information/ERLEADA-pi.pdf. This progress against some of the world's most challenging diseases is heartening but hard-won. Continued advancement will require perseverance and dedication. For example, we remain very committed to continuing research exploring new approaches and investigational medicines to prevent Alzheimer's dementia, which starts many years before the full onset of disease. In fact, we have invested billions of dollars in this area, and despite some significant projects that were halted because of lack of efficacy or a newly identified imbalance in benefit-risk, we continue to invest with the goal of conquering this --------------------------------------------------------------------------- major public health challenge in our lifetimes. Defeating Alzheimer's would not only change the lives of millions of patients and their families, it would dramatically change the economic burden of the disease. According to one analysis, if a new treatment that delays the onset of Alzheimer's by just five years were approved by 2025, the U.S. would save an estimated $367 billion each year by 2050.\14\ --------------------------------------------------------------------------- \14\ Alzheimer's Association. ``Changing the Trajectory of Alzheimer's Disease: How a Treatment by 2025 Saves Lives and Dollars.'' May 2015. https://www.alz.org/media/Documents/changing-the-trajectory- r.pdf. In fact, across a wide range of conditions, prescription medicines play a key role in keeping people well and productive and preventing the need for costly procedures and hospitalizations. For example, since the introduction of antiretroviral therapies, we've seen up to a $402,000 lifetime cost savings for each HIV patient diagnosed at an early stage.\15\ Cardiovascular medicines have led to a 27 percent reduction in costs for hospitalizations and procedures.\16\ In fact, the U.S. health-care system could save $213 billion annually with the correct use of prescription medications.\17\, \18\ --------------------------------------------------------------------------- \15\ Farnham, Paul G., Chaitra Gopalappa, Stephanie L. Sansom, Angela B. Hutchinson, John T. Brooks, Paul J. Weidle, Vincent C. Marconi, and David Rimland. ``Updates of Lifetime Costs of Care and Quality-of-Life Estimates for HIV-Infected Persons in the United States: Late Versus Early Diagnosis and Entry Into Care.'' Journal of Acquired Immune Deficiency Syndromes 64, no. 2 (2013): 183-189. doi: 10.1097/QAI.0b013e3182973966. \16\ Gotto, Antonio M., Stephen J. Boccuzzi, John R. Cook, Charles M. Alexander, James B. Roehm, Gregg S. Meyer, Michael Clearfield, Stephen Weis, and Edwin Whitney. ``Effect of Lovastatin on Cardiovascular Resource Utilization and Costs in The Air Force/Texas Coronary Atherosclerosis Prevention Study (AFCAPS/TexCAPS).'' The American Journal of Cardiology 86, no. 11 (2000): 1176-181. doi:10.1016/s0002-9149(00)01198-x. \17\ IMS Institute for Healthcare Informatics, ``Avoidable Costs in U.S. Healthcare'' (June 2013). http://offers.premierinc.com/rs/381-NBB- 525/images/Avoidable_Costs_in%20_US_Healthcare- IHII_AvoidableCosts_2013%5B1%5D.pdf. \18\ Roebuck, M.C., J.N. Liberman, M. Gemmill-Toyama, and T.A. Brennan. ``Medication Adherence Leads to Lower Health Care Use and Costs Despite Increased Drug Spending.'' Health Affairs 30, no. 1 (2011): 91-99. doi:10.1377/hlthaff.2009.1087. But medicines can't make a difference if patients who need them can't get them. We understand concerns about the cost of health care. Although prescription medicines represent only 14 percent of overall health-care spend--a figure that has remained relatively steady for the past decade and is projected to remain so into the future \19\--and 90 percent of prescriptions are filled with generics,\20\ managing the cost of medicines, particularly what patients pay at the pharmacy counter, is important. --------------------------------------------------------------------------- \19\ Altarum Institute. ``A 10-Year Projection of the Prescription Drug Share of National Health Expenditures, Including Nonretail.'' Report. August 2015. http://altarum.org/sites/default/files/uploaded- publication-files/Non-Retail%20Rx%20Forecast%20Data%20Brief%2010-14-14. pdf. \20\ IQVIA. ``2017 Medicine Use and Spending in the U.S. a Review of 2017 and Outlook to 2022.'' April 2018. https://www.iqvia.com/-/ media/iqvia/pdfs/institute-reports/medicine-use-and-spending-in-the-us- a-review-of-2017-and-outlook-to-2022.pdf. --------------------------------------------------------------------------- our approach to pricing At Janssen, we take a responsible approach to pricing that recognizes our dual responsibility to patients today and patients tomorrow. Patients today need access to our medicines. Patients tomorrow count on us to deliver cures and treatments for the most challenging, intractable diseases. When we set an initial price for our medicines, we balance: Value to patients, the health-care system, and society. We consider how the medicine will improve patient health and assess its potential to reduce other costs--surgeries, hospital stays, or long-term care, for example--and the improvement the medicine represents over the existing standard of care. Affordable access to medicines for people who need them. We want to ensure appropriate insurance coverage so that patients who are prescribed our medicines can get them. Ability to develop future groundbreaking cures and treatments. We have an obligation to ensure we have the resources necessary to invest in future R&D to address serious unmet medical needs. The list price of a medicine is a starting point that is ultimately reduced by the substantial discounts, rebates, and fees we provide to insurance companies, pharmacy benefit managers (``PBMs''), government programs, and others. We pay required discounts to government programs, and we negotiate with private payers so that they will cover our medicines and make them available to patients with lower out-of-pocket cost. In 2018, we provided approximately $21 billion in discounts and rebates on our medicines--an overall reduction from list price of 47 percent. For some of our medicines, and for some of our customers, we pay discounts, rebates, and fees totaling well over 50 percent of our list price--so middlemen in the supply chain in those cases realize a majority of the revenue. All told, while our 2018 aggregate list price increase was 6.3 percent,\21\ for the second year in a row discounts and rebates outweighed that increase, and aggregate net price--in other words, the real price--decreased by 6.8 percent.\22\ --------------------------------------------------------------------------- \21\ Represents the year-over-year change in the average list price, or wholesale acquisition cost (``WAC''). \22\ Represents the year-over-year change in the average net price, which is WAC less rebates, discounts, and returns. trends in pharmaceutical spending The fact is that across the industry net prices for branded medicines have increased well below the rate of medical inflation in recent years.\23\, \24\, \25\, \26\ In 2017, the total expenditure on pharmaceuticals in the U.S. grew by only 0.4 percent, compared to a 3.9 percent increase in overall health spending and a 4.6 percent increase in hospital spending.\27\ --------------------------------------------------------------------------- \23\ IQVIA INSTITUTE for Human Data Science. ``The Global Use of Medicine in 2019 and Outlook to 2023.'' Report. January 2019. https:// www.iqvia.com/-/media/iqvia/pdfs/institute-reports/the-global-use-of- medicine-in-2019-and-outlook-to-2023.pdf. \24\ U.S. Department of Labor. Bureau of Labor Statistics. ``Consumer Price Index--December 2016.'' News release, January 18, 2017. https://www.bls.gov/news.release/archives/cpi_01182017.pdf. \25\ U.S. Department of Labor. Bureau of Labor Statistics. ``Consumer Price Index--December 2017.'' News release, January 12, 2018. https://www.bls.gov/news.release/archives/cpi_01122018.pdf. \26\ U.S. Department of Labor. Bureau of Labor Statistics. ``Consumer Price Index--December 2018.'' News release, January 11, 2019. https://www.bls.gov/news.release/pdf/cpi.pdf. \27\ U.S. Centers for Medicare and Medicaid Services. ``NHE Fact Sheet.'' December 6, 2017. https://www.cms.gov/research-statistics- data-and-systems/statistics-trends-and-reports/national healthexpenddata/nhe-fact-sheet.html. Unfortunately, these trends are not reflected in many patients' experiences at the doctor's office or pharmacy counter. In fact, total patient out-of-pocket spending on medicines grew by 54 percent from 2006 to 2016.\28\ --------------------------------------------------------------------------- \28\ Claxton, Gary, Larry Levitt, Matthew Rae, and Bradley Sawyer. ``Increases in Cost-sharing Payments Continue to Outpace Wage Growth.'' Peterson-Kaiser Health System Tracker. June 15, 2018. https:// www.healthsystemtracker.org/brief/increases-in-cost-sharing-payments- have-far-outpaced-wage-growth/. One reason patient out-of-pocket spending has grown is due to changes in how health insurance is designed and, specifically, how pharmaceutical benefits are managed. As one recent analysis shows, patients are required to pay 13 percent of overall pharmaceutical costs versus only 3 percent of hospital costs--even though medicine can help keep patients out of the hospital.\29\ --------------------------------------------------------------------------- \29\ PhRMA. ``PhRMA Chart Packs: Biopharmaceuticals in Perspective.'' Report. 2018. https://www.phrma.org/report/chart-pack- biopharmaceuticals-in-perspective-summer-2018. The reality is that our health coverage system simply wasn't built in anticipation of medicines that treat diseases previously only treated with surgeries, hospitalizations and other complex interventions. Medicines today can extend and transform life for people facing very challenging, often relatively rare, diseases. It's critical that we work together to ensure that today's medicines are more accessible and affordable for patients while at the same time preserving the incredible ecosystem of medical innovation that has delivered so much and promises so much more. solutions to address the challenges we face Above all, we need an American solution to this American challenge. We must maintain the hallmarks that make American health care remarkable: access to innovative therapies, personal choice, and doctors and patients making decisions based on what is right for each individual. At Janssen, we are committed to being part of the solution. We believe open dialogue and partnership is essential to addressing the challenges in our health-care system. That's why in 2016 we began issuing an annual Janssen U.S. Transparency Report, sharing information about how we invest our resources, price our medicines, and help people who need Janssen medicines get access to them. Just recently, we expanded our commitment to transparency, announcing plans to voluntarily include list price and potential patient out-of-pocket costs in our pharmaceutical direct-to-consumer TV advertising, starting with our most frequently prescribed medicine. These more recent steps build on a legacy of commitment to transparency at Janssen. For example, we believe that making clinical trial data available promotes the understanding of disease, expands the knowledge needed to develop new treatments, and generates new insights and more complete evidence that lead to better health-care decisions for patients. In a first-of-its-kind agreement with the Yale University School of Medicine, we share clinical trial data through the Yale Open Data Access (YODA) Project. Since 2014, YODA Project has served as an independent review panel, evaluating researchers' requests for access to participant-level trial data and research reports, which provide extensive details about the methods and results of a clinical trial. Researchers can use these clinical trial data in their own research to increase medical knowledge and improve public health. In the same spirit of open dialogue and partnership, we have consistently brought forward ideas and perspectives to both Congress and the administration, with the goal of building on what is working in our healthcare system while fixing what is not: part d out-of-pocket cap While Medicare Part D is working for many seniors and has been effective in containing costs, we believe an out-of-pocket cap in Medicare Part D is a needed protection. Without a cap, Medicare beneficiaries face unlimited out-of-pocket expenses, and, as research shows, high out-of-pocket costs reduce patient adherence to prescribed treatments and make them more likely to abandon their prescriptions. Poor patient outcomes related to lack of adherence or abandonment of prescribed treatments can lead to an increase in overall health-care costs. Individual and group health insurance policies are already required to have out-of-pocket caps. We believe that Medicare, which serves some of the sickest and most vulnerable patients and is essential to the health of American seniors, should also have that protection. We have been working on policy approaches that would make it possible to implement an out-of-pocket cap in a fiscally responsible way without creating new costs or access barriers for patients. As Congress considers any changes to Part D, we look forward to discussing these ideas in more depth. medicare part b reform We believe policy solutions in Medicare Part B should meet three objectives: (1) reduce cost and spending; (2) increase competition; and (3) remove incentives to prescribe higher cost therapies without causing significant disruption to physicians or patient care. As changes to Part B are contemplated, it is important to remember that Medicare currently benefits from aggressive negotiations in the commercial market through the Average Sales Price (ASP) mechanism. Any reform should therefore leverage the benefits of the existing system. In our response to the Health and Human Services advance notice of proposed rulemaking regarding Part B, we proposed an option that would allow Medicare to continue to achieve the negotiated cost savings of the free market, reduce Part B acquisition cost under the ASP-based model, and reimburse all stakeholders on a fee-based mechanism aligned with the services that they provide. Our proposal aims to eliminate incentives for selecting higher list price drugs while maintaining current Part B patient access to appropriate clinical care. rebate reform We support reforms to the rebate system that restructure incentives to ensure patients benefit from a competitive marketplace and see lower out-of-pocket costs. In 2017, the pharmaceutical industry paid $150 billion in negotiated rebates and discounts.\30\ As we have noted, too often these rebates and discounts are not shared with patients, leaving the sickest patients paying higher out-of-pocket costs. We anticipate eliminating rebates could result in lower list prices, provided these rebates and discounts are not replaced with equally high fees or other payments demanded by middlemen. We also strongly advocate that beneficiary copays be based on net price. --------------------------------------------------------------------------- \30\ Adam J. Fein. ``The Gross-to-Net Bubble Topped $150 Billion in 2017.'' Drug Channels (April 24, 2018) (citing IQVIA Institute for Human Data Science. ``Medicines Use and Spending in the U.S.: A Review of 2017 and Outlook to 2022.'' Report. April 2018. https:// www.iqvia.com/institute/reports/medicine-use-and-spending-in-the-us- review-of-2017-outlook-to-2022. Altering the current rebate structure would be a major change to the entire pharmaceutical supply chain. It would need to be done thoughtfully and carefully to avoid disruption for patients. We look forward to commenting on the administration's proposed rule in this area. value-based care Our current system rewards the quantity or volume of care delivered, regardless of the results of that care. Consequently, sometimes we spend money on treatments, diagnostic procedures, and surgeries that provide limited value or may not even be needed, driving up health-care costs without actually improving patient health. At Janssen, we're working with partners throughout the health-care system to encourage more results-based health-care approaches. While we have negotiated several value-based contracts, current policy often limits our ability to implement creative solutions. To address policy barriers, we support the following measures: Establish safe harbors in the Federal Anti-Kickback Statute that better enable manufacturers to partner with payors and share risk; and, Clarify Medicaid pricing treatment, including existing Medicaid best price requirements that inhibit companies from offering arrangements that may yield lower price in some circumstances. promoting competition on a level playing field Biosimilars--near copies of biologic medicines--have the potential to increase competition and bring down costs, which is why Janssen has long supported a patient-focused, science-based regulatory framework for biosimilars. Some stakeholders have called for government to drive uptake by creating further incentives for biosimilars. But policies designed to increase share for biosimilar manufacturers would distort the competitive environment and risk limiting the savings biosimilars deliver to patients and taxpayers. We saw this risk realized most recently in the 340B Drug Discount Program, where policy designed to encourage the use of biosimilars had the unfortunate effect of increasing cost to patients, including low-income patients who can least afford it, and to taxpayers.\31\ --------------------------------------------------------------------------- \31\ Center for Biosimilars. ``340B Changes: What Biosimilar Manufacturers Need to Know.'' Feb. 19, 2018. https:// www.centerforbiosimilars.com/contributor/amanda-forys/2018/02/340b- changes-what-biosimilar-manufacturers-need-to-know. When it comes to making more biosimilars available for patients and their physicians, competition, not government intervention, is the best approach. And that approach is working. Not only is competition driving prices down for both innovator biologics and biosimilars, the biosimilars pipeline is strong. Competition on a level playing field will keep it that way. 340b policy At Janssen, we recognize that the 340B Drug Discount Program plays an important role in the healthcare system, helping to ensure that low- income, needy patients have appropriate access to medicine. However, congressional oversight, proper implementation, and equitable application of the program are essential to ensuring the 340B program is helping those it was designed to help. Under the 340B Drug Discount Program, we are required to provide significant discounts on certain medicines purchased by 340B covered entities (comprised of specific categories of hospitals, clinics, and health centers that meet Federal eligibility requirements). Growth in the 340B program has been well documented, and Janssen has experienced significant growth in this highly discounted channel as well. Although the program was intended to benefit needy patients, the facilities themselves receive the discounts. There is no requirement that 340B covered hospitals pass along those discounts to patients. 340B covered hospitals can therefore access 340B pricing on outpatient drugs for all of their patients, including wealthy and well-insured patients. A more direct and accountable link between the provision of the discount and patient access is needed. We believe the benefits of the program should flow more directly and transparently to needy patients. We support efforts to strengthen the 340B program through greater transparency and increased clarity and accountability for all stakeholders. These goals can be achieved through the establishment of clear, reasonable and auditable rules including a clear definition of ``patient'' as well as hospital eligibility criteria. conclusion We are here today at a moment of incredible hope, on the verge of extraordinary progress that could change our lives and the lives of our children and grandchildren. We have the opportunity to get this right for Americans today and for future generations. At Janssen, we are committed to bringing that promise to life with transformational medical innovation. ______ Questions Submitted for the Record to Jennifer Taubert Questions Submitted by Hon. Chuck Grassley spending on advertising/marketing vs. research and development Question. The Department of Health and Human Services' proposed rule, ``Fraud and Abuse; Removal of Safe Harbor Protection for Rebates Involving Prescription Pharmaceuticals and Creation of New Safe Harbor Protection for Certain Point-of-Sale Reductions in Price on Prescription Pharmaceuticals and Certain Pharmacy Benefit Manager Service Fees,'' envisions that drug manufacturers will offer up-front discounts rather than the back-end rebates that are now commonly provided. Some observers argue that a 1996 court case called into question whether manufacturers could offer up-front discounts, resulting in today's rebate-based system. I've heard differing opinions as to whether the issues related to the initial court case are still relevant. If the HHS proposed rule is finalized, can you assure the committee that your company will offer up-front discounts? If not, why? Please describe how you expect your company to respond to the HHS proposed rule to eliminate safe harbor protection for back-end rebates in Medicare Part D that is referenced above if it is finalized. Assuming you are confident that antitrust laws do not prevent your company from offering up-front discounts, specifically, do you envision that your company lowers the list price of a drug to the current after- rebate net price, offer discounts equal to the current rebate amount, or a combination of both? Answer. The 1996 antitrust law case cited, in our assessment, should not limit the ability to move from rebates to other types of discounts. Depending on whether elimination of rebates applies to the entire market or only to those related to Federal health plans and assuming rebates are not replaced by high fees or other costs that offset the amount saved, we expect to lower list prices or offer discounts for pass-through at the point of sale. In either case, we would need to renegotiate our agreements with customers. The degree to which we can convert current rebates to list price reductions or point-of-sale discounts will depend upon the details of the final regulation and the reactions of other stakeholders in the supply chain. We are concerned that PBMs may seek to replace rebate revenue with new and increasing fees or may seek to shift costs among supply chain participants through service fees. Question. To what extent are the back-end rebates your company currently offers contingent on the amount of market share realized for your drugs as a result of Part D plan formulary placement and other techniques? Answer. Janssen does not currently offer rebates contingent on the amount of market share for our drugs as a result of Medicare Part D formulary placement. In other words, Janssen's current Medicare Part D rebate agreements do not contain any market share performance requirement. Question. Please provide a breakdown of percentage of sales that go to each payer (including Medicare, Medicaid, private pay, other) and a similar percentage by volume of the total number of each drug compared to total volume. Please provide this data for the most recent year available. Answer. Potentially responsive information may not be maintained by the company in the ordinary course of business. As such, an answer to this question is not readily available. Question. Do your companies hire consultants or lobbyists to promote products at State Medicaid Pharmacy and Therapeutics Committees? To whom do you disclose advocacy activities surrounding State Medicaid programs, if at all? Answer. Janssen does not hire external lobbyists or consultants for the purpose of promoting products at State Medicaid Pharmacy and Therapeutics Committees. We have internal employees who register as lobbyists and provide information about Janssen products to State Medicaid Pharmacy and Therapeutics Committee personnel. We comply with varied State laws regarding advocacy, including disclosure requirements. Question. Please describe how the costs of patient assistance programs are accounted for within your company's financial statements. Please also describe the types of market information, such as prescribing and use patterns, that your company collects from different types of patient assistance programs and patient hub services. Answer. Our patient assistance programs include both commercial copay support programs and charitable donations, which include both financial contributions and pharmaceutical products. With respect to Janssen's copay card programs, the value of patient copayment support is recorded as a reduction in sales revenue. The administrative costs associated with implementing the copayment programs are captured in selling, marketing and administrative expenses on Johnson & Johnson's SEC Form 10K. With respect to the company's charitable free product programs, Janssen donates prescription products to the Johnson & Johnson Patient Assistance Foundation, Inc. (``JJPAF''), a 501(c)(3) organization with an independent board and decision-making. Janssen also makes financial contributions to JJPAF and other independent 501(c)(3) organizations. These product and financial donations are recorded as charitable deductions. With respect to our commercial patient assistance programs, we collect information that is needed to support administering the program, helping patients get access to the medically appropriate treatment they have selected, and identifying and addressing barriers to patient access. Question. Please provide a list of all contributions since January 1, 2014, that your company has made to any tax-exempt organizations working on issues related to drugs within your product lines, including but not limited to patient groups, disease awareness groups, medical or professional societies, universities or hospitals, industry associations or leagues. For each contribution, please provide the name of the organization that received the donation, the date the donation was made, the amount of the donation, and a description of the purpose of the contribution (i.e., was the contribution for the general fund, a specific purpose to a specific program, or continuing medical education). Please also note whether the contribution was unrestricted or restricted; if it was restricted, please explain all restrictions. Finally, if your company maintains a foundation or other separate charitable arm, please provide the name of all such entities, and list all donations made from that entity or entities. Answer. Through our Janssen charitable giving, we're proud to make a difference for patients and for the communities where we live and work. Janssen provides charitable donations through an established application review and approval process designed to ensure that the recipient of any contribution (i) is a valid 501(c)(3) charitable organization; (ii) has an established, good reputation; and (iii) is not on a Federal exclusion list (if the non-profit is a provider or government contractor). In addition, the charitable contributions review process is designed to review requests for donations to make sure that they are not made for the purpose of inducing the use or recommending the use of any J&J product. Janssen releases a contributions transparency report (``Contributions Report'') that details all of the charitable donations from the company for the prior year. Please see the attached link for the most recently posted Contributions Report, https://www.janssen.com/ us/transparency/educational-charitable-contribution-disclosures. With respect to the Contributions Report, please note: In keeping with our donor agreements and applicable regulatory guidance, financial donations made to independent charitable foundations that assist patients who are underinsured and in need of financial assistance with treatment-related expenses are disclosed in aggregate on the Janssen Contributions Report. Charitable contributions made by recently acquired company Actelion are not included in our report. In future years, these donations will be included in the Contributions Report. Donations in the amount of $270,000 have been made annually to support the mission of PhRMA Foundation. These donations were made on April 29, 2014; January 21, 2015; December 21, 2015; September 11, 2017; June 1, 2018; and January 15, 2019. Contribution Reports for years 2014 through 2017 are attached. Most donation requests seek support for a specific program or initiative. If approved, the use of the contributed funds will be restricted to the purpose set forth in the application request. The Contribution Report details this purpose in the project title section. In addition, the company's standard donation agreement used for most contributions stipulates that funds should not be used to (i) educate, train or support meals, salary, travel, consulting fees or any other reimbursement to U.S.-licensed physicians; or (ii) fund services for which the organization receives government reimbursement under a fee-for-service model. Janssen makes financial contributions and prescription product donations to the Johnson & Johnson Patient Assistance Foundation, Inc. (``JJPAF''), a 501(c)(3) organization with an independent board and decision-making. The JJPAF provides free products directly to patients who meet certain income requirements and who do not have insurance coverage. In limited circumstances, JJPAF may work with other non- profit entities to distribute products to patients in need. JJPAF does not advise Janssen of the specific recipients of its donations. In 2018, Janssen donated approximately $1 billion in free product and financial support to the JJPAF, enabling it to provide medicines at no cost to approximately 76,000 patients. The Johnson & Johnson Foundation (``JJF'') is a private non-profit 501(c)(3) organization, founded in 1953. Solely funded by the Johnson & Johnson Family of Companies, the Foundation is responsible for managing the Corporation's Global Community Impact (``GCI'') programs and activities across the globe. Donations made by this foundation are available publicly through the IRS Form 990 it submits each year. Question. Pay-for-delay agreements cost consumers and taxpayers billions in higher drug costs every year. The FTC has gone after drug companies that enter into these settlements where the brand pays the generic company to keep its lower cost alternative off the market. I'm the lead Republican sponsor of S. 64, the Preserve Access to Affordable Generics and Biosimilars Act, which would help put an end to these deals. Do you agree that these pay-off agreements keep drug costs high for patients because they delay competition? Has your company ever entered into these kinds of settlements with a generic company? Do you support the pay for delay bill? Answer. J&J has not entered into patent settlement agreements that require payment of money to a generic manufacturer. Since J&J has not entered into agreements of this type, we do not have direct experience with their competitive impacts. The current legal framework--FTC oversight and judicial review on a case-by-case basis--is intended to identify any patent settlement that is anti-competitive. It is important to note that not all settlement agreements would result in a delay in competition; for example, some agreements of this type might facilitate generic entry prior to patent expiry. Although we believe that the current legal framework is sufficient to ensure that patent settlements are not anti-competitive, we would not oppose pay-for-delay legislation, provided that such legislation clearly, and in a manner consistent with current case law, defines the specific features of settlement agreements within its scope, does not hinder the ability of parties to utilize settlement agreements to efficiently settle patent disputes, and allows for an assessment of the competitive impacts of individual settlement agreements on a case-by- case basis. rebate traps/walls Question. I'm increasingly concerned about the effect of so-called ``rebate traps'' or ``rebate walls'' on patients' access to quality, lower cost medicine. I understand there is ongoing litigation challenging these practices as anti-competitive. Does your company engage in the bundling of rebates over multiple products? If so, why? And what benefit does the consumer gain from that? Answer. Like other companies with broad portfolios of medicines that are highly valued by payers, health-care providers, and patients, Janssen offers incremental value when customers make a broader range of our medicines available to patients. Similar programs are common in the pharmaceutical and other industries. These programs provide an incentive for the customer to utilize our products and can lower costs. Those savings may be passed through to patients. Question. Does your company view these practices as anticompetitive or harmful to patients' access to quality, lower cost medicine? Answer. Janssen's contract offerings encourage price competition among drug manufacturers and ultimately enhance patients' access to quality medicines at lower prices. Question. If a policy were adopted to eliminate rebates, or to require that rebate savings be passed on to the consumer, would that in and of itself solve the issue of rebate ``traps'' and ``walls''? And would consumers benefit from such a policy? Answer. We support reforms to the rebate system that restructure incentives to ensure patients benefit from a competitive marketplace and see lower out-of-pocket costs. It is important to note that in today's health-care marketplace, payers use their ability to influence utilization to extract rebates, thereby enhancing competition and lowering overall system costs. Unfortunately, these savings are not usually shared with patients. Similarly, if rebates are eliminated, we anticipate that payers will use their ability to influence utilization to extract discounts and fees from manufacturers. drug pricing Question. When setting the list price of a drug, does your company consider regulatory costs or compliance? If so, how specifically do those factors affect the list price of a drug? Please provide at least one specific example, if applicable, from your current product portfolio. When setting the list price of a drug, does your company consider the risk of liability or litigation? If so, how specifically do those factors affect the list price of a drug? Please provide at least one specific example, if applicable, from your current product portfolio. Answer. At Janssen, we take a responsible approach to pricing that recognizes our dual responsibility to patients today and patients tomorrow. Patients today need access to our medicines. Patients tomorrow count on us to deliver cures and treatments for the most challenging, intractable diseases. When we set an initial list price for our medicines, we balance: Value to patients, the health-care system, and society. We consider how the medicine will improve patient health. We also assess the medicine's potential to reduce other costs--surgeries, hospital stays, or long-term care, for example--and the improvement the medicine represents over the existing standard of care. The importance of maintaining affordable access to medicines for people who need them. We work with insurers, pharmacy benefits managers, governments, hospitals, physicians, and other providers of care so that patients who are prescribed our medicines can get access to them. The importance of preserving our ability to develop future groundbreaking cures and treatments. We have an obligation to ensure that the sale of our medicines provides us with the resources to invest in R&D to address serious, unmet medical needs. In addition, the sale of our medicines must enable us to cover the costs of compliance with all laws and regulations. Regarding the requests for specific examples from our current product portfolio, the information requested is confidential and competitively sensitive. As such, potentially responsive information is not available for public disclosure. ______ Questions Submitted by Hon. Pat Roberts Question. What role do you see value-based arrangements (VBAs) playing in the effort to reduce prescription drug costs? What potential do these arrangements have to find the ``sweet spot'' between controlling costs to patients and encouraging innovation of new drugs? Answer. We believe a value-based health-care system has tremendous potential to improve patient health, increase access to care, and curb the growth in health-care spending. Our current health-care system rewards the quantity or volume of care delivered, regardless of the results of that care. Consequently, sometimes money is spent on treatments, diagnostic procedures, and interventions that provide limited value or may not even be needed, driving up healthcare costs without actually improving patient health. Shifting to a value-based system requires innovation in the way contracts between payers and manufacturers are structured. By creating common incentives to deliver value for patients, value-based agreements, including innovative approaches to contracting models, can provide better outcomes at lower costs. We have established several innovative, value-based contracts and continue to explore new opportunities. For example, we have contracts tied to measurable medical outcomes and contracts tied to offsets of other expenditures. Fundamentally we believe a value-based health system will drive down the amount of waste in our current health-care system, so the money spent actually makes a measurable difference in individual health and the health of our society overall. Efforts to achieve a more value- based system have encouraged all stakeholders to more clearly define and measure the value of health-care services offered, including medicines. In a health-care system that rewards value over volume, we believe incentives will be greater to bring to market new drugs that can reduce the need for other costly health-care intervention and ultimately produce better health outcomes and lower cost. Question. How can VBAs help lower what patients pay out-of-pocket? Answer. Innovative contracting models can align the incentives of all stakeholders, including pharmaceutical companies, health-care providers, and payers, to achieve better outcomes for patients at a lower overall cost of care to the health-care system, including Federal programs. In most cases, because the pharmaceutical company agrees to share some of the risk around the economics of the arrangement for a particular medicine, the health plan or PBM will provide better access to that medicine, which may entail placing the medicine on a lower formulary tier. Lower formulary tier placement results in lower out-of- pocket costs for patients. We know that rising patient copayments are a barrier to adherence and therefore to optimal outcomes. We believe that keeping out-of-pocket costs reasonable for patients is an important element of getting to better outcomes, and innovative contracts can support this goal. According to an analysis by PhRMA and Avalere Health, commercially insured patients in health plans with outcome-based contracts for diabetes, high cholesterol and HIV medicines between 2015 and 2017 had copays that were, on average, 28 percent lower for those medicines compared to patients in other plans. Question. Can Congress do more to allow for and encourage the use of VBAs? Answer. We are enthusiastic about the potential for expanding the use of innovative value-based agreements. Nevertheless, a number of technological and policy barriers can make these agreements challenging to implement. To address technological barriers, we advocate for modernizing our healthcare data system to make it easier to track patient outcomes. To address policy barriers, we support the following approaches: establishing safe harbors to better enable manufacturers to partner with payers and share risk; clarifying the treatment of value- based contracts in government price calculations, including in the complex Medicaid Best Price determination; and making comparative formulary and cost-sharing information readily available so patients have the information they need to make better decisions. ______ Questions Submitted by Hon. John Cornyn Question. We continue to hear that rebates negotiated off of the list price of a drug are both good and bad. Pharmacy benefit managers and plans have argued that rebates are used to lower premiums across the board and that it is the best way to seek a price concession on otherwise expensive drugs. Your industry argues that these payers are insisting on higher rebates that can only be achieved by raising list prices. But patients often lose under this system, with out of pocket costs being tied to list price. Insulin patients appear to be routinely impacted by this perversity in the system. Please explain to the committee how your company would reduce list prices if rebates were no longer a part of the equation? What assurance can you provide that you would in fact lower your prices? What actions should be taken to ensure that patients are actually seeing the benefits of lower out of pocket costs? Answer. Depending on whether elimination of rebates applies to the entire market or only to those related to Federal health plans and assuming rebates are not replaced by high fees or other costs that offset the amount saved, we expect to lower list prices or offer discounts for pass-through at the point of sale. In either case, we would need to renegotiate our agreements with customers. The degree to which we can convert current rebates to list price reductions or point-of-sale discounts will depend upon the details of the final regulation and the reactions of other stakeholders in the supply chain. We are concerned that PBMs may seek to replace rebate revenue with new and increasing fees or may seek to shift costs among supply chain participants through service fees. We support reforms to the rebate system that restructure incentives to ensure patients benefit from rebates and discounts that are provided. Question. If rebates are driving high list prices for drugs as drug manufacturers' claim, why do you think that Part B drugs, which have no PBM rebates, are also seeing significant price increases? Whose fault is that? Answer. Part B benefits from competitive commercial rebates and discounts, while maintaining access to medicines for our nation's seniors, through the Average Selling Price (``ASP''). ASP, which is the basis for Part B drug reimbursement, reflects all commercial discounts and rebates. Since both provider reimbursement and patient out-of- pocket costs for Part B drugs are based on ASP, changes in a product's ASP is a more relevant indicator of true cost to the Medicare system and beneficiaries. ______ Question Submitted by Hon. Michael B. Enzi Question. The Food and Drug Administration's drug review process is known to many as the ``gold standard'' for evaluating medical products. I've long thought that it is critical that we maintain public confidence in their ability to ensure that drugs are safe and effective. There is a perception among some, however, that biosimilars might not be as safe as their reference products. That perception can undermine patient and provider confidence. Do you believe that when FDA approves a biosimilar, providers can be confident that it is safe and effective? Answer. Biosimilars granted licensure by the FDA are by definition safe and effective and are highly similar to the reference biologic. We support the FDA's application of rigorous scientific standards and appropriate data requirements for the licensure of both biosimilars and interchangeable biosimilars, and we believe evidence and experience will drive patient and provider confidence in these products. ______ Questions Submitted by Hon. Todd Young re-evaluating business strategies in foreign countries Question. Since taking office, President Trump has made reducing drug prices one of his highest priorities--and has repeatedly spoken about his frustration with the U.S. subsidizing the costs of pharmaceuticals for the rest of the world. He has gone so far as to issue proposals, like the International Pricing Index (IPI) Model, in an attempt to bring down prescription drug prices. With the increased scrutiny of the industry and of the drug supply chain as a whole in the United States, have any of your companies re- evaluated your business strategy in foreign countries? If not, then why? If a proposal, like IPI, were implemented, would it force your companies to potentially ``walk away from the negotiating table when other countries demand low prices subsidized by America's seniors,'' as HHS Senior Advisor for Drug Pricing Reform John O'Brien has said? What are some of your ideas on how we can ensure Americans aren't shouldering the full cost of pharmaceuticals? Answer. We continuously evaluate our global business strategy and country- specific market access approaches in light of current conditions, including changing policies and circumstances. We support the use of trade tools to improve the policy environment for U.S. companies operating overseas and to enhance incentives for innovation. The U.S. government has already taken steps to advance this goal with some of our key trading partners. The U.S. Mexico Canada Agreement (``USMCA'') includes important provisions committing Canada and Mexico to recognize the value of pharmaceuticals either through the operation of competitive markets or through procedures that appropriately value pharmaceuticals. The agreement also contains procedural safeguards for U.S. companies. These include a requirement that Canada and Mexico provide opportunities for stakeholder comment on measures before they are finalized and also offer U.S. companies an opportunity to appeal administrative actions. These are critical tools that will help American companies obtain fair value for innovation outside the U.S. The U.S. government has announced its intention to negotiate trade agreements with Japan, the European Union, and the United Kingdom. These negotiations could address inadequacies in the systems of some our largest trading partners. The U.S. government can also effectively leverage existing trade agreements and tools like Organisation for Economic Cooperation accession negotiations to induce foreign governments to provide appropriate value for innovation and offer greater incentives for new treatments and cures. foreign countries' pricing and reimbursement Question. President Trump and Secretary Azar have both repeatedly described their frustrations with ``foreign freeloading'' of U.S. drugs in the last year. ``When foreign governments extort unreasonably low prices from U.S. drug makers, Americans have to pay more to subsidize the enormous cost of research and development. . . . It's unfair and it's ridiculous, and it's not going to happen any longer.'' Do you agree that because of foreign countries' pricing and reimbursement systems, U.S. patients and innovators are shouldering the burden for financing medical advances? Answer. According to a report by the U.S. Department of Commerce, international reference pricing and controls suppress worldwide private research and development by up to 16 percent annually, leading to fewer new medicines launched each year. Conversely, recent estimates demonstrate that removing price controls in other wealthy countries would increase the number of available new treatments by 9 percent by 2030, equivalent to a range of 8 to 13 new therapeutics that year. Question. How do foreign countries' pricing and reimbursement systems affect our prescription drug costs? Answer. While there is no direct relationship between U.S. drug prices and foreign prices, according to a report by the U.S. Department of Commerce, existing foreign price controls suppress worldwide private research and development and decrease the number of new treatments and cures, to the detriment of U.S. patients. It is important to note that most cross-country pricing comparisons focus solely on the list prices of medicines and do not account for the significant discounts required for participation in U.S. public programs, such as Medicaid, the 340B Drug Discount Program, and the Federal Supply Schedule (for U.S. Department of Veterans Affairs and the Department of Defense), as well as the discounts and rebates negotiated by private payers. For this reason, most international comparisons are not ``apples to apples.'' In addition, in other countries, medicine prices are achieved through national regulation, which often restricts or delays access to innovative medicines and limits patient and physician choice. Question. Are foreign governments taking note of the concerns being raised by the Trump administration and have they responded in any way? Answer. We understand that some foreign government officials have noted the concerns raised by the Trump administration and appear to be seeking a better understanding of the proposed policy changes in the United States and the potential future impacts on their countries. Question. Has there been any noticeable change in any of our trade agreements since these concerns have been raised by the Trump administration? Answer. The U.S.-Mexico-Canada Agreement (``USMCA'') contains important provisions on intellectual property that establish a higher global IP standard than in previous agreements, particularly with respect to data protection for biologics. The agreement also contains important provisions committing Canada and Mexico to recognize the value of pharmaceuticals either through the operation of competitive markets or through procedures that appropriately value pharmaceuticals. The agreement includes procedural safeguards for U.S. companies. These include a requirement that Canada and Mexico provide opportunities for stakeholder comment on measures before they are finalized and also offer U.S. companies an opportunity to appeal administrative actions. These are critical tools that will help American companies obtain fair value for innovation. The U.S. government has announced its intention to negotiate trade agreements with Japan, the European Union, and the United Kingdom. These negotiations could address inadequacies in the systems of some our largest trading partners. The U.S. government can also effectively leverage existing trade agreements and tools like Organisation for Economic Co-operation accession negotiations to induce foreign governments to provide appropriate value for innovation and offer greater incentives for new treatments and cures. medicaid closed formulary proposals Question. In an attempt to bring down drug costs, various states have been exploring whether to exclude certain drugs from its Medicaid program. For example, the state of Massachusetts' recently asked CMS for permission to create a closed formulary where the state Medicaid program would pick at least one drug per therapeutic class. CMS denied their waiver request citing violation of federal law, but this proposal does bring up important questions on how to contain drug prices in state Medicaid programs. If the principles of the Medicare Part D program--including the necessary patient protections--were applied to State Medicaid programs, do you think it would lower drug costs while ensuring access to patients? Answer. By legislative design, the Medicaid Program already receives the ``best'' price, in addition to substantial rebates associated with an inflation penalty and negotiated supplemental rebates. The rebate is never less than 23.1 percent, the required statutory minimum, and often requires manufacturers to sell their products (both older and newer) for as low as 1 cent per pill or unit. The Medicaid drug rebate statute represents a carefully crafted legislative approach developed by Congress and designed as a package to offer Medicaid beneficiaries comprehensive coverage and access to outpatient drugs at the lowest cost in the marketplace. We support the significant access protections required under the current Medicaid Drug Rebate Program that serve a uniquely vulnerable population. We also question whether reducing access to medically necessary medication for vulnerable Medicaid beneficiaries will yield true program savings. Any further restrictions in medication access is likely to increase the risk of higher costs elsewhere in the health-care continuum. Moreover, vulnerable Medicaid beneficiaries may be particularly challenged to navigate the administrative, technical, logistical and other challenges that inevitably arise when additional restrictions are placed on their access to care. medicaid ``best price'' Question. In the Trump administration's Blueprint, they suggested that because drug manufactures have to give Medicaid the ``best price'' on drugs, there is no incentive to offer deeper discounts to other payers--both government and commercial--than what is already offered under the Medicaid Drug Rebate Program. Does the Medicaid ``best price'' requirement encourage manufacturers to increase initial prices? Answer. We take into account the Medicaid ``best price'' requirement at all stages of the drug lifecycle, including launch. We consider best price when offering large discounts to commercial customers after a drug is launched and when designing value-based agreements. Question. What, if any, changes would you suggest we make to the program? Answer. We are supportive of ongoing efforts to promote a value- driven health-care system, including in Medicaid, and applaud recent efforts by both the administration and Congress that seek to address regulatory and legal uncertainty around value-based payment arrangements. We also support CMS's recent approvals of State proposals to advance specific Medicaid value-based arrangements with drug makers. outcomes-based contracts Question. In almost all of your testimonies, you highlight your support of outcomes-based contracts and how we need to be shifting our system toward that approach. How will these contracts lower drug costs for patients in both the near term and long-term? How will they lower overall health-care costs for our Federal programs? What have the preliminary results looked like so far? Answer. Innovative contracting models can align the incentives of all stakeholders, including pharmaceutical companies, health-care providers, and payers, to achieve better outcomes for patients at a lower overall cost of care to the health-care system, including Federal programs. In most cases, because the pharmaceutical company agrees to share some of the risk around the economics of the arrangement for a particular medicine, the health plan or PBM will provide better access to that medicine, which often entails placing the medicine on a more preferable formulary tier. More preferable formulary tier placement results in lower out-of-pocket costs for patients. We know that rising patient copayments are a barrier to adherence and therefore to optimal outcomes. We believe that keeping out-of-pocket costs reasonable for patients is an important element of getting to better outcomes, and innovative contracts can support this goal. According to an analysis by PhRMA and Avalere Health, commercially insured patients in health plans with outcome-based contracts for diabetes, high cholesterol and HIV medicines between 2015 and 2017 had copays that were, on average, 28 percent lower for those medicines compared to patients in other plans. Innovative contracting models are still relatively new, and we look forward to the point at which we will have the long-term data necessary to evaluate the success of these programs with respect to health-care cost reduction. We are enthusiastic about the potential of innovative value-based contracting models to enable us to take full advantage of medicines' benefits, including their potential to reduce other health- care costs. transparency/point of sale Question. In almost all of your testimonies, you express your support for the Trump administration's proposal to allow manufacturers to provide PBMs up-front discounts that are passed onto patients at the point of sale. Do you feel like this proposal will make the transactions within the drug supply chain more transparent? If so, would this transparency bring down drug costs--overall and for specialty drugs? Answer. We do believe that a point-of-sale discount model, wherein manufacturer discounts could be passed through to a patient at the point-of-sale, will make price reductions offered by the manufacturer more transparent because these discounts would be more directly reflected in patient out-of-pocket cost at the pharmacy. However, we do not believe that the proposal will improve transparency with respect to fees or mark-ups to the price of drugs added elsewhere in the supply chain. Depending on whether elimination of rebates applies to the entire market or only with respect to Federal health plans and assuming rebates are not replaced by high fees or other costs that offset the amount saved, we expect to lower list prices or offer discounts for pass-through at the point of sale. the relationship between wholesalers and manufacturers Question. When talking about the pharmaceutical supply chain, a lot of focus has been placed on the pharmacy benefit manager. But there's another side of the equation that I'd like to ask about: how do wholesalers negotiate pricing with manufacturers? Answer. Janssen sells to wholesalers and specialty distributors at list price, with discounts customarily offered for prompt payment. Janssen occasionally offers discounts to wholesalers for discrete periods of time on certain products. These are generally offered to contracted, authorized wholesalers market-wide. In addition, Janssen negotiates service agreements with wholesalers and specialty distributors for bona fide services relating to distribution of Janssen products. Question. What impact does this have on drug costs? Answer. We do not know the details of the wholesalers' arrangements with downstream stakeholders such as pharmacies, hospitals, providers, and other sites of care. Question. What incentives or disincentives do they have to contain price increases? Answer. We are not in a position to comment on wholesaler incentives or disincentives to contain price increases. ______ Questions Submitted by Hon. Ron Wyden proposed rebate rule Question. As has been done in many other settings, drug manufacturers said during the hearing that one reason list prices for drugs are high is that pharmaceutical benefit managers (PBMs) demand larger and larger rebates in order for the drug to receive favorable placement on a formulary. You and your colleagues who testified during the hearing stated if the administration's proposal on changes to the anti-kickback safe harbor for pharmaceutical rebates took effect, your company would likely lower list price. Like many Oregonians, I am skeptical drug manufacturers would voluntarily lower their prices. Therefore, would you support legislation that would (1) make similar changes the administration has put forward related to Part D and Medicaid managed care, (2) change the rebate system in a similar way to the proposal for the commercial market, and (3) require drug makers to lower the list price of their drugs equal to the amount of rebates provided today? Answer. We support reforms to the rebate system that restructure incentives to ensure patients benefit from a competitive marketplace and see lower out-of-pocket costs. Depending on whether elimination of rebates applies to the entire market or only to those related to Federal health plans and assuming rebates are not replaced by high fees or other costs that offset the amount saved, we expect to lower list prices or offer discounts for pass-through at the point of sale. In either case, we would need to renegotiate our agreements with customers. The degree to which we can convert current rebates to list price reductions or point-of-sale discounts will depend upon the details of the final regulation and the reactions of other stakeholders in the supply chain. We are concerned that PBMs may seek to replace rebate revenue with new and increasing fees or may seek to shift costs among supply chain participants through service fees. medicaid drug rebate program Question. The Medicaid Drug Rebate Program (MDRP) requires manufacturers to provide a basic rebate and an additional inflationary rebate for both brand and generic drugs. The inflationary rebate is an increasingly substantial part of total rebates due in large part to large increases in drug prices that exceed inflation. Under current law, this inflationary rebate is capped at 100 percent of Average Manufacturer Price (AMP). This is the case even when manufacturers continue to raise their prices well above inflation. Please provide a list of all of your pharmaceutical products that have reached the Medicaid AMP rebate cap in any of the 20 quarters from January 1, 2014 through December 31, 2018. For each drug listed in response to question 1, please also provide a list of which quarters and years each drug hit the cap. Answer. Janssen has numerous current products, and products that have since been sold to third parties, that have reached the Medicaid AMP rebate cap in at least one of the 20 quarters from 1Q 2014 through 4Q 2018. The fact that these products reaching the 100 percent AMP cap is based on confidential metrics reported under the Medicaid Drug Rebate Program. The Medicaid AMP rebate cap is reached when AMP is less than or equal to the Unit Rebate Amount (URA). URA is calculated based on AMP and Best Price--which are confidential under the Medicaid Drug Rebate statute at 42 U.S.C. ' 1396r8(b)(3)(D). There are exceptions in the statute that permit the Secretary and State Medicaid agencies to disclose the information only in certain situations, including disclosure to CBO. Thus, if there was legislation proposing to amend the 100 percent AMP cap, CBO would be able to access the drugs and underlying data to estimate the cost/savings to the government of such a legislative change. The product-specific information requested is confidential and competitively sensitive. As such, potentially responsive information is not available for public disclosure. medicaid drug rebate program compliance Question. I am concerned about recent reports and legal settlements surrounding drug manufacturers' failure to comply fully with the requirements of the MDRP. For example, an analysis by the U.S. Department of Health and Human Services Office of Inspector General found that between 2012 and 2016 taxpayers may have overpaid by as much as $1.3 billion for 10 potentially misclassified drugs. That is why I introduced the Right Rebate Act with Chairman Grassley to prevent drug manufacturers from manipulating Medicaid to increase their profits. However, I continued to be concerned about oversight and manufacturer compliance with the requirements of the Medicaid Drug Rebate Program. Accordingly, please describe the following: Your company's current compliance plan and procedures used to ensure compliance with the requirements of the Medicaid Drug Rebate Program including internal audits or other checks you use to identify compliance vulnerabilities. Any past or ongoing issues of non-compliance. Any corrective actions taken to address identified problems or issues of non- compliance with the MDRP and how such steps were communicated to the Centers for Medicare and Medicaid Services. Any steps taken to improve compliance and ensure that all Medicaid drug rebates owed to the Federal Government and the States are paid in full. Answer. We comply with the obligations we undertake when participating in U.S. Federal, State, or local government contracts and government pricing programs such as the Medicaid Drug Rebate Program. We have an established compliance framework along with organizational structure and accountabilities designed to assure compliance. Our framework includes testing and monitoring and an obligation to correct any identified discrepancies. As such, any discrepancies have been timely addressed and corrected. The other information requested is confidential. As such, potentially responsive information is not available for public disclosure. bonus payments tied to specific drugs Question. I am concerned by the potential for employee financial incentives to encourage high launch prices and price increases for prescription drugs. Is your salary, bonus or other compensation tied to sales or revenue targets of a single product your company sells? Has it ever been? If yes, please state the product or products to which your salary, bonus or other compensation was tied. Answer. At no time during her employment with the Johnson & Johnson Family of Companies has Ms. Taubert's salary, bonus, or other compensation been tied to sales or revenue targets of a single product. Question. Is your salary, bonus, or other compensation tied to either revenue or net income of the company as a whole? Has it ever been? If yes, please explain what assumptions about price increases are used when the compensation committee sets revenue or net income goals. Does the compensation committee provide any guidance to executives in regards to the amount of revenue that the company will generate from price increases versus volume growth? Answer. We structure performance-based compensation to reward an appropriate balance of short-term and long-term financial and strategic business results, with an emphasis on managing the business for long- term results. Our compensation program's emphasis on long-term value reduces the possibility that our executives make excessively risky business decisions that could maximize short-term results at the expense of long-term value. Ms. Taubert's base salary is tied to performance, market data, responsibilities, time in position, internal equity, and experience. Ms. Taubert's bonus and long-term incentive compensation has been and is awarded based on her individual performance and the company's performance. The compensation committee does not provide guidance to executives regarding the amount of revenue that the company will generate from price increases versus volume growth. provision of rebates in exchange for formulary placement Question. In today's system, drug makers receive a limited time window to sell their drug without competition. After that period has expired, low-cost generics should become available. However, drug makers often prevent access to these cheaper generic drugs in Medicare. Researchers have found that 72 percent of Medicare Part D plans charged lower cost-sharing for a brand name drug compared to its generic equivalent. This means seniors were charged less out of pocket for brand name drugs compared to generics that are on average four times cheaper than the brand-named drug. This happens because drug makers pay a rebate to the Part D plans in order to give the more expensive drug better treatment than a generic. As a result, Medicare spending increases due to the current structure of the Part D benefit. Has your company ever paid a rebate to a Part D plan so that a brand name drug would get preferential treatment (i.e., lower cost- sharing or less utilization management) compared to a cheaper generic? If so, please provide: a list of the drugs for which your company has done this since January 1, 2014; and the number of Part D plans in which this type of rebate was given for each drug in each year. Answer. In negotiations with PBMs and payers, Janssen may offer multiple different rebate options. The PBM or payer has sole discretion over how formularies are structured. In some cases, a PBM or payer may establish a formulary that puts a branded drug in a preferential position. The information requested is confidential and competitively sensitive. As such, potentially responsive information is not available for public disclosure. net prices Question. Your testimony stated that ``while our 2018 aggregate list price increase was 6.3 percent, for the second year in a row discounts and rebates outweighed that increase, and aggregate net price--in other words, the real price--decreased by 6.8 percent.'' According to your testimony, the net price ``represents the year-over- year change in the average net price, which is WAC less rebates, discounts, and returns.'' Please describe how the company's year-over- year aggregate net price is calculated. Please also specifically address the following questions: Answer. Average net price change represents the year-over-year change in the average net price, which is Wholesale Acquisition Cost less rebates, discounts, and returns. Question. How many products are included in the calculation of the average net price change? What was the median net price change? Answer. We believe weighted average net price change is the appropriate metric for evaluating list price changes across the portfolio. There are 99 products (brands) included in the average net price change calculation. The 2017-2018 weighted average net price change is -6.8 percent. The non-weighted average 2017-2018 net price change is -3.7 percent. The 2017-2018 median net price change is -1.9 percent. It is important to note that non-weighted average or median net price change treats all medicines--whether used by many patients or by very few--equally, so those figures are not useful or valuable in understanding the actual change experienced. Question. Is net price weighted? If so, how? For example, in determining the aggregate net price does the company assign different weights to different products based on volume or other factors? Are ``on patent'' and ``off patent'' drugs weighted identically? Are other statistical weights used or are all products treated equally? Answer. Annual net price change versus prior year is calculated at the product level and weighted across the company's U.S. product portfolio using net trade sales. All products, both ``on patent'' and ``off patent,'' are included. Question. Does the figure that you provided during your testimony account for U.S. prices, international prices, or both? Generally speaking, when your company reports net price changes, does it differentiate between U.S. and international prices? Answer. The figure provided, -6.8 percent, accounts for 2018 net price change for our U.S. pharmaceutical business only. We disclose this figure in our annual Janssen U.S. Transparency Report. Question. Please list the five drugs your company sold in the U.S. that had the greatest year-over-year net price increase in 2018, noting the increase for each drug by dollar figure and percentage. Please list the five drugs your company sold in the U.S. that had the lowest year- over-year net price increase (and/or the greatest decrease) in 2018, noting the increase (or decrease) for each drug by dollar figure and percentage. Answer. The information requested is confidential and competitively sensitive. As such, potentially responsive information is not available for public disclosure. Question. For 2018, what was the average net price change in the U.S. market for (1) drugs with no competition, (2) drugs with only branded competition, and (3) drugs with generic competition? Answer. The information requested is confidential and competitively sensitive. As such, potentially responsive information is not available for public disclosure. Question. Your company noted in its annual financial filing with the Securities and Exchange Commission that ``Immunology was negatively impacted by lower sales of REMICADE' (infliximab) due to increased discounts/rebates and biosimilar competition,'' and ``Strong sales of long-acting injectables INVEGA TRINZA'/ TREVICTA' (paliperidone palmitate) and INVEGA SUSTENNA'/XEPLION' were partially offset by cannibalization of RISPERDAL CONSTA' (risperidone) and generic competition for CONCERTA'/methylphenidate,'' and ``Lower sales of INVOKANA'/INVOKAMET' (canagliflozin) in the U.S. was primarily due to an increase in price discounts, higher rebates and market share decline driven by competitive pressure. Lower sales of XARELTO' (rivaroxaban) were driven by an increase in discounts and rebates, partially offset by an increase in market share.'' What were the year-over-year net price changes for each of these drugs? Answer. The information requested is confidential and competitively sensitive. As such, potentially responsive information is not available for public disclosure. Question. Please define the following terms that were used on page 20 of your company's annual report for the year ending December 31, 2018 regarding sales of various pharmaceutical products: strong uptake, market growth, and share gain. Please also define ``reduction in sales,'' as used in the sentence ``Biosimilar versions of REMICADE' have been introduced in certain markets outside the U.S., resulting in a reduction in sales of REMICADE' in those markets.'' Answer. ``Strong uptake'' means that we are seeing significant utilization of a medicine that was recently introduced into the market or approved for a new indication. ``Market growth'' refers to increase in utilization of medicines overall for a particular disease state or in a particular class of medicines. ``Share gain'' means that within a class of medicines or therapeutic area, a particular medicine is being selected and utilized more than it had been previously and now represents a greater percentage of utilization within that class relative to competitor medicines. ``Reduction in sales'' in the sentence you reference means that revenues for REMICADE' are lower than they have been in previous years. Please note that our 2018 Annual Report goes on to state, ``In the U.S., a biosimilar version of REMICADE' was introduced in 2016, and additional competitors continue to enter the market. Continued infliximab biosimilar competition in the U.S. market will result in a further reduction in U.S. sales of REMICADE'.'' ______ Questions Submitted by Hon. Robert Menendez Question. During the hearing, when I asked whether your company engaged in tactics to delay generic production of your products, you answered ``no.'' However, your Johnson & Johnson's Actelion appears on the FDA's list of companies who have access complaints against them. Can you explain the discrepancy between your answer and the FDA list? The FDA list can be found here: https://www.fda.gov/Drugs/ DevelopmentApprovalProcess/HowDrugsareDevelopedandApproved/ ApprovalApplications/AbbreviatedNewDrugApplicationANDAGenerics/ ucm607738.htm. Answer. Johnson & Johnson acquired Actelion in June 2017. We share FDA's commitment to policies that promote access to generics when balanced with the protection of innovation and the safeguarding of patient safety. It is important to note that the FDA's website on Reference Listed Drug (``RLD'') Access Inquiries does not differentiate between inquiries and complaints, and does not clarify whether the RLD Sponsor made samples available after the FDA issued a Safety Determination Letter. Following the receipt of a Safety Determination Letter from the FDA, Actelion has actively entered into a supply agreement with every generic manufacturer who has requested testing samples of our products. This is true for each instance cited in the FDA's RLD Access Inquiry list. Actelion is also actively engaging with generic manufacturers to develop shared REMS programs that protect patient safety while enabling patient access to our medicines. Question. When new products enter the market, do drug companies set high initial rebates and then provide deep rebates in order to gain access to insurance plan's formularies? Answer. At Janssen, we take a responsible approach to pricing that recognizes our dual responsibility to patients today and patients tomorrow. Patients today need access to our medicines. Patients tomorrow count on us to deliver cures and treatments for the most challenging, intractable diseases. When we set an initial list price for our medicines, we balance: Value to patients, the health-care system, and society. We consider how the medicine will improve patient health. We also assess the medicine's potential to reduce other costs--surgeries, hospital stays, or long-term care, for example--and the improvement the medicine represents over the existing standard of care. The importance of maintaining affordable access to medicines for people who need them. We work with insurers, pharmacy benefits managers, governments, hospitals, physicians, and other providers of care so that patients who are prescribed our medicines can get access to them. The importance of preserving our ability to develop future groundbreaking cures and treatments. We have an obligation to ensure that the sale of our medicines provides us with the resources to invest in R&D to address serious, unmet medical needs. We go through a lengthy process to gather the information necessary to assess the medicine according to these factors. We use this information to determine the value of our medicine compared to what is, or will be, available to treat the same condition--be it other medicines, surgery, or other forms of health care. Question. If CMS finalizes the rebate rule, do you anticipate future products entering the market with significantly lower initial list prices? Answer. Depending on whether elimination of rebates applies to the entire market or only to those related to Federal health plans and assuming rebates are not replaced by high fees or other costs that offset the amount saved, we expect to lower list prices or offer discounts for pass-through at the point of sale. In either case, we would need to renegotiate our agreements with customers. The degree to which we can convert current rebates to list price reductions or point-of-sale discounts will depend upon the details of the final regulation and the reactions of other stakeholders in the supply chain. We are concerned that PBMs may seek to replace rebate revenue with new and increasing fees or may seek to shift costs among supply chain participants through service fees. ______ Questions Submitted by Hon. Thomas R. Carper Question. What are your recommendations for lowering prices for the 40 percent of drugs that do not offer rebates in Medicare Part D? In the health insurance plans that you offer your employees, do you ask your insurers to pass through the full manufacturer rebates to the beneficiaries? Answer. Drugs that offer lower rebates tend to be drugs that face less competition in the marketplace. Increased competition can lead to lower prices of branded and generic drugs. FDA Commissioner Scott Gottlieb prioritized faster approval of generic drugs. In 2018, FDA set a record by approving an estimated 971 generic drugs. Within today's health-care system, we do recover manufacturer rebates from our PBM. Any savings we receive are used to offset out-of- pocket costs for employees and total plan costs. In order to help ensure affordability for our employees, we limit out-of-pocket pharmacy costs through a monthly per prescription cap. Question. The systems for pricing and distributing drugs are opaque and difficult to understand. What are your recommendations for increasing transparency in how your companies set the list prices for drugs, and for improving transparency in the supply chain for prescription drugs? Would you support federal standards for transparency in setting the list prices for drugs? Answer. At Janssen, we issue an annual U.S. Transparency Report that explains what we take into account in setting list prices for our medicines. When we set an initial list price for our medicines, we balance: Value to patients, the health-care system, and society. We consider how the medicine will improve patient health. We also assess the medicine's potential to reduce other costs-- surgeries, hospital stays, or long-term care, for example--and the improvement the medicine represents over the existing standard of care. The importance of maintaining affordable access to medicines for people who need them. We work with insurers, pharmacy benefits managers, governments, hospitals, physicians, and other providers of care so that patients who are prescribed our medicines can get access to them. The importance of preserving our ability to develop future groundbreaking cures and treatments. We have an obligation to ensure that the sale of our medicines provides us with the resources to invest in R&D to address serious, unmet medical needs. The list price we set is a publicly available figure that can be-- and is-- compared to other options available. We believe that a point- of-sale discount model will make price reductions offered by the manufacturer more transparent because these discounts will be directly reflected in patient out-ofpocket cost at the pharmacy. However, we do not believe that the proposal will improve transparency with respect to fees or mark-ups to the price of drugs added elsewhere in the supply chain. Transparency that is meaningful and valuable to patients can help achieve what we all want: better health care, at more manageable cost, and, most importantly, longer, healthier lives for all. We believe an environment that encourages medical innovation and robust competition to deliver the best health outcomes is essential to achieving these goals. Our support for legislation that establishes a federal standard for transparency in setting the list price for drugs would depend on the extent to which the proposed standards maintained such an environment. Question. In nearly every sector of the health-care industry, Medicare, Medicaid, employers, and insurers are moving away from fee- for-service payments to reimbursements based on value and performance. Prescription drugs and medical devices were the glaring exceptions to this trend until recently. How many of your drugs are included in value-based contracts and how many patients are benefiting from them? How do these value-based contracts work to lower drug prices for both patients and taxpayers? Answer. We have established several innovative, value-based contracts with insurers and continue to explore new opportunities. For example, in immunology, we partnered with payers to create an agreement in which the price of a medicine for chronic immune conditions varies based on how well it works for patients. In oncology, we partnered with public and private payers on novel contracts for patients with prostate cancer and agreed in one contract to provide additional rebates to the insurer for plan members who meet eligibility criteria and whose treatment duration is shorter than a predetermined period of time. We also partnered with a leading payer on a contract under which we are paid more if data show our medicine that treats adults with type 2 diabetes contributed to lowering other identified health-care costs, such as the use of additional medicines. Question. Last year, Senator Portman and I did an investigation on the pricing of an opioid overdose reversal drug called EVZIO, manufactured by Kaleo. Kaleo increased the price of EVZIO from $575 in 2014 to $4,100 in 2017. We found that the best price Medicare was able to get for EVZIO, about $4,000, was much higher than the price other Federal programs and private insurers were able to get. It seemed that Kaleo was able to get this higher price of $4,000 from Medicare by helping doctors fill out paperwork showing that the drug was medically necessary, even though there are cheaper alternatives on the market. As a result of the investigation, Kaleo announced it will bring a generic version of the drug to market at only $168 per pack. Are any of your companies providing medical necessity paperwork to doctors in order to get your drugs covered by Medicare? Answer. Like other pharmaceutical companies, we offer a sample letter of medical necessity that offices can complete using their own clinical judgment regarding the medical and clinical rationale for submission to the insurance company or PBM. We also research and provide payer-specific forms required to provide medical necessity information such as payer-specific prior authorization forms. Question. In 2017, the Rand Corporation estimated that biosimilar drugs, which are competitors to complex, biologic drugs, could save the United States more than $50 billion over the next decade. Some of you have also argued that increasing the use of biosimilar drugs would help lower drugs costs for consumers and taxpayers. What is delaying the uptake of biosimilar drugs in the United States? What policies do you recommend to increase the development of biosimilar drugs? Answer. The goal of biosimilar policy should be to lower costs for the health-care system and patients, and not simply to encourage biosimilar uptake without regard to price. The current open and competitive environment supports price competition and biosimilar uptake as appropriate. For example, the net price of infliximab products, including the innovator product REMICADE', is falling. Furthermore, the uptake of infliximab biosimilars in the U.S. is consistent with branded biologic launches of immunology products, including those that provide a clinical benefit over the standard of care. Biologics are used in patients with serious, chronic conditions, many of whom have taken years to become stable on a branded product. Health-care providers and patients may naturally be hesitant to switch medicines in these circumstances. The approval of an interchangeable biosimilar may address some of the physician and patient reservations about switching a stable patient to a non-interchangeable biosimilar. The biosimilars pipeline is strong and a diverse group of companies--traditional pharmaceutical manufacturers as well as manufacturers focused on biosimilars--is investing in the space. For example, in the immunology therapeutic area alone, at least 18 biosimilars are currently in clinical development or undergoing FDA review. We fully support a regulatory framework for FDA review and approval of biosimilars and interchangeable biosimilars with standards and policies that are science-based and rooted in patient safety. Ultimately, the uptake of biosimilars will be reliant on competitive pricing and on patient and prescriber confidence. Provider and patient confidence can be strengthened by the application of rigorous review standards, including the robust approach to interchangeability that FDA is pursuing and appropriate standards regarding biosimilar to biosimilar switching. Biosimilar manufacturers need access to samples of reference products to perform comparative testing required to demonstrate biosimilarity or interchangeability. We cooperate with manufacturers of generic drugs and biosimilars so they have access to samples of our medicines at reasonable, market-based prices. To facilitate access to product samples while fostering efficiencies in the delivery and oversight of healthcare, we believe that manufacturers should identify for FDA a point of contact to facilitate access to samples for each approved reference product. When a Risk Evaluation and Mitigation Strategy (REMS) is in place, the REMS should facilitate the safe use of medicine and ensure access for appropriate patients; it should not be used to hinder provision of product samples for use in developing a generic or biosimilar. We believe FDA should finalize draft guidance, issued December 2018, describing a process for FDA determination that protocols pertaining to biosimilarity and interchangeability testing contain safety protections comparable to an applicable REMS with limited distribution elements. A letter from FDA stating comparable protections exist and indicating FDA would not consider it to be a violation of the REMS to provide samples to the biosimilar manufacturer provides needed assurances for reference product manufacturers about both the safe use of our products and regulatory compliance. The Purple Book is an essential resource for many stakeholders and should be enhanced to provide timely information to stakeholders, to clarify practices regarding substitution, and to provide information to assure the appropriate use of biosimilars and interchangeable products. In addition, the Purple Book should include detailed information about approved biosimilars and interchangeable biosimilars, including, for example, a description or listing of pivotal clinical trials considered in FDA's approval of the biosimilar. ______ Questions Submitted by Hon. Benjamin L. Cardin Question. The United States is one of the only countries in the world to allow prescription drug manufacturers to advertise directly to consumers through magazines, billboards, radio, and television commercials. While I will not argue that it is beneficial to educate consumers about an unfamiliar disease and encourage them to seek medical help, most commercials from all of your companies recommend asking about a specific brand name drug, not a medical condition. Furthermore, even if your advertisements follow all FDA rules and list medication side effects, they also almost always list these while a smiling, apparently healthy person is walking on a beach. Researchers say that this type of imagery, combined with viewing hours of drug commercials each month, leads consumers to underestimate the risks associated with medications. For the past decade, studies have shown that aggressive direct-to-consumer advertising is associated with rising drug prices and an increase in inappropriate drug prescriptions. Since researchers have concluded that consumers are misunderstanding the benefits and risks described in your ads, what further policies could help you and your colleagues ensure that you are educating patients in a clear manner? Answer. At Janssen, we believe patients can get and stay healthier when they are well informed about their conditions and treatment options. We provide accurate, up-to-date educational materials in language that is clear and understandable for consumers to help patients facing diseases our medicines treat and to help patients who take our medicines understand how to use them properly. Our product- specific communications, including our DTC advertising, are designed to encourage appropriate dialogue between patients and healthcare providers about the risks and benefits of treatment. We believe acting ethically and responsibly is not only the right thing to do but also the right way to do business. We follow all relevant laws and regulations regarding the promotion of prescription drug products and submit promotional materials to the U.S. Food and Drug Administration at the time of initial publication or dissemination. We are always open to ways to improve our communication, including DTC, to ensure patients better understand the benefits and risks of our medicines. pharmaceutical companies continue to raise prices Question. As you are well aware, high prescription drug prices are the number one concern for Americans and their families. According to the Organisation for Economic Co-operation and Development, the average American spends around $1,208 annually on prescription drugs. There have been several instances where brand name or even generic drugs that have been on the market for years continue to increase in price. One of the most well-known examples is Mylan's increase of the price of EpiPen from less than $100 in 2007 to more than $600 in 2016. Another example, is the ever-increasing price of insulin. Sanofi increased the price of a vial of Lantus from $88.20 in 2007 to $307.20 in 2017. And those are just a small sample of price increases. Why don't we see price decreases for drugs that have been on the market for years without new formulations or added benefit? Answer. In fact, net price does often decrease, sometimes quite significantly, for medicines that have been on the market for years because of competition from other, newer medicines for the same condition. Competition brings down price for payers such as PBMs and insurers, although unfortunately patients often do not benefit from the lower net price. It is also important to note that biopharmaceutical innovation paves the way for the introduction of generic medicines, which enables medicine costs to be reduced over time. In the U.S., medicines lose patent protection, on average, about 12 years after they are introduced. When that happens, prices generally drop significantly, giving patients ongoing access to effective therapies at a lower cost. pay for delay Question. Pay for delay is a tactic that more and more branded drug manufacturers have been using to stifle competition from lower-cost generic manufacturers. This allows you to sidestep competition by offering patent settlements that pay generic companies not to bring lower-cost alternatives to market. These pay-for-delay patent settlements benefit both brand-name pharmaceutical companies by helping them avoid costly patent litigation and general manufacturers by rewarding them a hefty sum to delay entering the market with a cheaper drug alternative. However, these deals do not benefit consumers. According to an FTC study, these anticompetitive deals cost consumers and taxpayers $3.5 billion in higher drug costs every year. Does your company partake in pay-for-delay settlements? Answer. We have not entered into patent settlement agreements that require payment of money to a generic manufacturer. Question. Why would a pharmaceutical company enter into a pay-for delay agreement? Answer. We have not entered into patent settlement agreements that require payment of money to a generic manufacturer and, therefore, we cannot speculate as to why other companies might enter into such agreements in specific cases. Question. Do you think these agreements stifle competition and prevent generic alternatives to your branded medications? Answer. We have not entered into patent settlement agreements that require payment of money to a generic manufacturer, so we do not have direct experience with their competitive impacts. However, we believe that the competitive impact of any individual settlement agreement must be evaluated on a case-by-case basis. The current legal framework--FTC oversight and judicial review on a case-by-case basis--is intended to identify any patent settlement that is anti-competitive. drug rebate rule Question. In January, the Department of Health and Human Services' (HHS) Office of Inspector General (OIG) promulgated a new regulation to remove regulatory safe harbor protections under the Anti-Kickback Statute (AKS) for rebates on prescription drugs rebates paid by manufactures to PBMs under Medicare Part D and for Medicaid managed care organizations (MCOs). The OIG proposal attempts to ban most rebates by eliminating their regulatory protections. The rule is predicted to increase net drug costs in its early years. The CMS actuaries estimate it would cost $196 billion over 10 years. Despite this high price tag, the beneficiary benefits are limited. The proposed rule notes that under the CMS Actuary's analysis, the majority of beneficiaries would see an increase in their total out- of-pocket payments and premium costs; reductions in total cost sharing will exceed total premium increases. I wanted to ask a question about the administration's rebate rule, which I understand that many of the drug manufacturers, and your main trade association, strongly support. According to an analysis of the rule by the Office of Actuaries at CMS, drug manufacturers are likely to initially retain 15 percent of the current rebates as higher net drug prices. Given that estimate, can you provide the committee with any assurances that prices will not increase under this proposed rule? Answer. Depending on whether elimination of rebates applies to the entire market or only to those related to Federal health plans and assuming rebates are not replaced by high fees or other costs that offset the amount saved, we expect to lower list prices or offer discounts for pass-through at the point of sale. In either case, we would need to renegotiate our agreements with customers. The degree to which we can convert current rebates to list price reductions or point-of-sale discounts will depend upon the details of the final regulation and the reactions of other stakeholders in the supply chain. We are concerned that PBMs may seek to replace rebate revenue with new and increasing fees or may seek to shift costs among supply chain participants through service fees. ______ Questions Submitted by Hon. Sherrod Brown Question. As I understand it, 2 years ago PhRMA updated its membership standards to require member companies to meet two new criteria: (1) each company must meet a 3-year average global research and development to sales ratio of 10 percent or greater, and (2) each company must spend at least $200 million on R&D per year over a 3-year average. As a result of these changes, several companies who continue to operate under business models that prioritize price gouging over innovation, left PhRMA. Given your company's role in setting a higher standard for R&D, would you support a more even playing field by raising the minimum bar for R&D across the entire pharmaceutical sector, in particular for companies that participate in government programs such as Medicare and Medicaid? Answer. We are proud to set a high standard for R&D investment. In 2018 Janssen invested $8.4 billion globally in research and development. This investment in R&D was 86 percent more than we spent on sales and marketing. However, we would not support a policy that requires a certain amount of R&D spending for a manufacturer's products to be covered by Medicare and Medicaid because we would not want to deny patients access to needed medication based on the investment decisions of these drug companies. Question. According to an article recently published in the Journal of the American Medical Association, medical marketers spend nearly $30 billion dollars in 2016, up from $17 billion in 1997. Direct-to- Consumer (DTC) advertising had the biggest percentage increase: from $2.1 billion, or 11.9% of all medical marketing, in 1997 to $9.6 billion, or 32% of total spending, in 2016. Can you please provide what your ratio of spending on sales and marketing to research and development is today? Answer. In 2018, the pharmaceutical segment of Johnson & Johnson invested 86 percent more in R&D globally ($8.4B) than we spent on global sales and marketing ($4.5B). price-gouging Question. Sanofi, as I understand it, has made a pledge to the public to limit its price increases to the national health expenditures growth projection. Would your company commit to a cap on annual price increases as part of your PhRMA membership criteria? Answer. In 1993, the Pharmaceutical Manufacturers Association (PMA, now the Pharmaceutical Research and Manufacturers of America or PhRMA) asked the Department of Justice (``DOJ'') Antitrust Division to review a proposal for a PMA effort to ask member companies to commit voluntarily to limiting price increases on their entire line of prescription medicines in any calendar year to an amount not to exceed the increase in the Consumer Price Index (CPI). In its response, the DOJ Antitrust Division stated that, ``[T]he Department believes that the proposed program would violate the antitrust laws. . . . The Supreme Court has. . . made clear that agreements that set maximum prices are as equally illegal as agreements that set minimum prices.'' The DOJ noted that it ``intends to bring suit to challenge the program if PMA and its members go forward with this proposal.'' Therefore, we are unable to commit to such a cap as part of PhRMA membership requirements due to likely enforcement action by the DOJ. Question. What policies would you propose to help ensure lower launch prices for new drugs? Answer. We support rebate reforms that ensure patients benefit from negotiated rebates and discounts--$150 billion in 2017 alone--and, as a result, have patients see lower out-of-pocket costs at the pharmacy. Depending on whether elimination of rebates applies to the entire market or only to those related to Federal health plans and assuming rebates are not replaced by high fees or other costs that offset the amount saved, we expect to lower list prices or offer discounts for pass-through at the point of sale. In either case, we would need to renegotiate our agreements with customers. The degree to which we can convert current rebates to list price reductions or point-of-sale discounts will depend upon the details of the final regulation and the reactions of other stakeholders in the supply chain. We are concerned that PBMs may seek to replace rebate revenue with new and increasing fees or may seek to shift costs among supply chain participants through service fees. transparency Question. In many of your testimonies, you mentioned that the current system of pharmacy benefit manager (PBM) back-end rebates do not rarely results in a scenario where the PBM passes on savings to consumers at the point of sale (POS). The administration recently proposed a rule to eliminate the anti-kickback statute safe harbor protections for these drug rebates. Do you agree that greater transparency should be required to understand how manufacturers and PBMs are negotiating prices and rebates to ensure that savings are passed down to beneficiaries? Answer. We believe that a point-of-sale discount model will make price reductions offered by the manufacturer more transparent because these discounts will be directly reflected in patient out-of-pocket cost at the pharmacy. However, we do not believe that the proposal will improve transparency with respect to fees or mark-ups to the price of drugs added elsewhere in the supply chain. Depending on whether elimination of rebates applies to the entire market or only to those related to Federal health plans and assuming rebates are not replaced by high fees or other costs that offset the amount saved, we expect to lower list prices or offer discounts for pass-through at the point of sale. pbms Question. An Axios article from March 7, 2019 highlights the fact that, while ``pharmaceutical companies put a lot of the blame for high drug prices on pharmacy benefit managers,'' many large pharmaceutical companies ``rely on PBMs to manage their own health-care benefits.'' In your role as an employer, does your company contract with a pharmaceutical benefit manager (PBM) to administer the prescription drug benefits for your employees and negotiate lower drug costs on your behalf? Answer. As an employer, we design our own pharmacy benefit program and contract with a PBM for administration and to negotiate on our behalf. Question. For those of you who do use a PBM to help manage the prescription drug benefit for your employees, how do you utilize the rebates your PBM negotiates to lower health-care costs or drug costs for your employee plans and what does your company do with that savings? Specifically, do the savings go toward lowing premiums? Answer. We use any savings to offset total plan costs, enhance benefits, and lower premium and out-of-pocket costs for our employees. In order to ensure our employees have affordable access to medicine, we have a monthly per prescription out-of-pocket cap. Question. For those of you who do use a PBM to help manage the prescription drug benefit for your employees, does your PBM offer point-of-sale rebates to your employees? Answer. We are exploring the possibility of offering point-of-sale rebates with our PBM. ______ Questions Submitted by Hon. Sheldon Whitehouse Question. Please describe any policy changes you support that would result in your company lowering the list prices of its drugs. Answer. We support rebate reforms that ensure patients benefit from negotiated rebates and discounts-- $150 billion in 2017 alone--and, as a result, have patients see lower out-of-pocket costs at the pharmacy. Depending on whether elimination of rebates applies to the entire market or only to those related to Federal health plans and assuming rebates are not replaced by high fees or other costs that offset the amount saved, we expect to lower list prices or offer discounts for pass-through at the point of sale. In either case, we would need to renegotiate our agreements with customers. The degree to which we can convert current rebates to list price reductions or point-of-sale discounts will depend upon the details of the final regulation and the reactions of other stakeholders in the supply chain. We are concerned that PBMs may seek to replace rebate revenue with new and increasing fees or may seek to shift costs among supply chain participants through service fees. Question. How much does your company's research and development portfolio rely on taxpayer-funded research conducted by the National Institutes of Health (NIH)? How many of your company's products are based, at least in part, on NIH research, and how many are the result of research funded solely by your company? Answer. The NIH plays an important role in medical research, primarily funding basic research on medical problems. The pharmaceutical industry is responsible for developing the solutions-- undertaking the long, financially risky, and costly process to discover a compound and develop new medicines that meet the stringent safety and efficacy requirements of the FDA. In those instances where NIH contributes to a product that is brought to market, NIH would receive any contracted license fees or royalties. Question. In each of the last 5 years, how much has your company spent on research and development versus the advertising and marketing of your products? Answer. Below is a chart including global Janssen R&D and Sales and Marketing expenditures over the last 5 years. Sales and marketing includes expenses related to: (1) selling, (2) marketing management, (3) market and consumer research, and (4) advertising and promotion. ------------------------------------------------------------------------ 2014 2015 2016 2017 2018 ------------------------------------------------------------------------ Janssen R&D $6.2B $6.8B $7B $7.9B $8.4B ------------------------------------------------------------------------ Janssen Sales and Marketing $4.5B $4.6B $4.5B $4.2B $4.5B ------------------------------------------------------------------------ Question. During the hearing, you mentioned that your company would be likely to lower the list prices of its drugs if the recent proposal by the Trump administration to change the current system of rebates was extended to the private market. If the policy was extended to the private market, how large would the list price reductions be relative to the size of the rebates your company is currently providing? How will this proposal affect how your company sets the list prices for new drug products? Answer. Depending on whether elimination of rebates applies to the entire market or only to those related to Federal health plans and assuming rebates are not replaced by high fees or other costs that offset the amount saved, we expect to lower list prices or offer discounts for pass-through at the point of sale. In either case, we would need to renegotiate our agreements with customers. The degree to which we can convert current rebates to list price reductions or point-ofsale discounts will depend upon the details of the final regulation and the reactions of other stakeholders in the supply chain. We are concerned that PBMs may seek to replace rebate revenue with new and increasing fees or may seek to shift costs among supply chain participants through service fees. Question. If the proposal is finalized and not extended to the private market, will your company make any list price reductions? If so, how large would the reductions be relative to the size of the rebates your company is currently providing? Answer. If elimination of rebates applies only to Medicare and Medicaid Managed Care and assuming rebates are not replaced by high fees or other costs that offset the amount saved, we expect to offer discounts for pass-through at the point of sale. To do so, we would need to renegotiate our agreements with customers. The degree to which we can convert current rebates to point-of-sale discounts will depend upon the details of the final regulation and the reactions of other stakeholders in the supply chain. We are concerned that PBMs may replace rebate revenue with new and increasing fees or may shift costs among supply chain participants through service fees. ______ Question Submitted by Hon. Maggie Hassan Question. In June of 2018, the Medicaid and CHIP Payment and Access Commission (MACPAC) unanimously recommended under Recommendation 1.1 in their annual report to Congress that Congress remove the statutory requirement that manufacturers blend the average manufacturer price (AMP) of a brand drug and its authorized generic.\1\ --------------------------------------------------------------------------- \1\ MACPAC, ``Improving Operations of the Medicaid Drug Rebate Program,'' https://www.macpac.gov/wp-content/uploads/2018/06/Improving- Operations-of-the-Medicaid-Drug-Rebate-Program.pdf. This requirement created an unintended loophole. Rather than use the price of the authorized generic, drug companies can sell its authorized generic to a corporate subsidiary at an artificially lower price, and use that lower price to bring down the AMP, which in turn --------------------------------------------------------------------------- lowers the rebate obligation. Does your company engage in this practice? Has your company ever engaged in this practice in the past? Answer. We do not include authorized generic internal transfer prices to an affiliate when calculating Average Manufacturer Price for the branded product. Under previous versions of the statute and CMS guidance, we have at times in the past included in Average Manufacturer Price the transfer prices of our authorized generic sold to an affiliate. ______ Questions Submitted by Hon. Catherine Cortez Masto Question. As a portion of your revenue, for what percentage of the drugs in your portfolio do you offer no rebates? Based on the drugs in your pipeline, do you foresee that portion growing? For those drugs is your list price equal to your net price? Answer. The information requested is confidential and competitively sensitive. As such, potentially responsive information is not available for public disclosure. Question. Do you invest more in R&D than you generate in US sales revenue? Please include specific figures. Answer. Janssen is one of the world's top R&D investors in any industry, anywhere in the world. In 2018 we invested $8.4 billion in pharmaceutical R&D globally. Our pharmaceutical revenue in the U.S. was $23.3 billion. We invested 86 percent more in pharmaceutical R&D ($8.4 billion) than we spent on pharmaceutical global sales and marketing ($4.5 billion). Question. Do you invest more in R&D than you spend on marketing and administration? What company functions do you consider to be included in administration? Please include specific figures. Answer. Johnson & Johnson is comprised of three business segments: pharmaceuticals (Janssen), medical devices, and consumer products. In its financial statements, Johnson & Johnson reports a global total figure across all segments for Sales, Marketing and Administration (``SM&A''). This figure combines marketing, sales, and administrative expenses such as insurance, legal, finance, and product distribution. In 2018, that global, cross-sector SM&A expenditure was $22.54 billion. The total global, cross-sector R&D investment by J&J in 2018 was $10.78 billion. Johnson & Johnson does not report SM&A by business segment. Janssen, the pharmaceutical segment of J&J, invested $8.4 billion in R&D globally in 2018 and spent $4.5 billion on marketing and sales globally. Question. Do you invest more in R&D than you spend on marketing and sales? What company functions do you consider to be included in sales? Please include specific figures. Answer. In 2018, we invested 86 percent more in pharmaceutical R&D ($8.4 billion) than we spent on pharmaceutical global sales and marketing ($4.5 billion). Sales and marketing includes: (1) our expenses related to selling, (2) marketing management, (3) market and consumer research, and (4) advertising and promotion. Question. Why do you advertise for the drugs you manufacture? What factors do you consider in choosing which drugs you advertise? Answer. We believe direct-to-consumer communication, including advertising, can empower patients with information to help them have appropriate discussions with their healthcare providers, including dialogue about the risks and benefits of treatment. We provide accurate, up-to-date educational materials to help patients facing diseases our medicines treat and to help patients who take our medicines understand how to use them properly. We believe acting ethically and responsibly is not only the right thing to do but also the right way to do business. We follow all relevant laws and regulations regarding the promotion of prescription drug products and submit promotional materials to the U.S. Food and Drug Administration at the time of initial publication or dissemination. We work to communicate in ways that will be most valuable in empowering patients to have appropriate dialogue with their healthcare providers. We consider the availability of information and awareness of treatment options. We build a communication plan that can include a variety of channels, with direct-to-consumer advertising being one channel among many we may use. ______ Janssen Biotech, Inc. Monetary and Product Contributions to U.S.-based Charitable Organizations Full Year 2014 (Payments made from January 1, 2014 to December 31, 2014)--Amended March 19, 2019 ------------------------------------------------------------------------ Payment Donation Payee Payee Amount Payment Project Title/ Type Address (USD) Date Description ------------------------------------------------------------------------ Monetary 100 4631 $1,000 8/29/2014 100 Black Men Black Delmar of Metro St. Men (of Boulevard Louis, St. Metro , St. Louis, MO St. Louis, MO Louis) 63108 ------------------------------------------------------------------------ Monetary Abington 515 $300 8/29/2014 Abington Art Art Meetingho Center, Center use Road Jenkintown, Jenkintow PA (2014 n, PA Janssen 19046 Cares Volunteer Days) ------------------------------------------------------------------------ Monetary Aldie 11 Welden $300 9/10/2014 Aldie Foundat Drive Foundation, ion Doylestow Doylestown, Inc. n, PA PA Janssen 18901 Cares Volunteer Days ------------------------------------------------------------------------ Monetary American 2600 US $1,000 4/21/2014 Run for Dad Cancer Highway 1 Prostate Society North Cancer event North in Hamilton, Brunswick NJ , NJ 08902 ------------------------------------------------------------------------ Monetary Arthriti 115 NE $5,000 8/29/2014 Arthritis s 100th Foundation, Foundat Suite Seattle, WA-- ion #350 Great West Seattle, Region JBRs WA 98125 ------------------------------------------------------------------------ Monetary Arthriti 1876 $6,000 11/10/2014 Jingle Bell s Minnehaha Run/Walks Foundat Avenue Upper ion West St. Midwest Paul, MN 55104 ------------------------------------------------------------------------ Monetary Arthriti 35 East $10,000 8/29/2014 AF, Chicago, s Wacker IL 2014 Foundat Drive Heartland ion Suite Region 2260 Jingle Bell Chicago, Runs and IL 60601 Walks ------------------------------------------------------------------------ Monetary Arthriti 4300 $7,000 12/22/2014 Arthritis s McArthur Foundation, Foundat Suite 245 Dallas, TX-- ion Dallas, JBRs South TX 75209 Central Region ------------------------------------------------------------------------ Monetary Arthriti 4530 Park $5,000 8/29/2014 Arthritis s Road Foundation, Foundat Charlotte Charlotte, ion , NC NC--2014 29209 JBRs ------------------------------------------------------------------------ Monetary Arthriti 4630 $7,500 10/3/2014 Arthritis s Richmond Foundation, Foundat Road Cleveland, ion Suite 240 OH JBRs Cleveland , OH 44128 ------------------------------------------------------------------------ Monetary Arthriti 800 West $12,500 11/13/2014 Jingle Bell s Sixth Run/Walks, Foundat Street Los Angeles ion Suite CA 1250 Los Angeles, CA 90017 ------------------------------------------------------------------------ Monetary Arthriti 8383 North $1,000 11/13/2014 Arthritis s Davis Foundation, Foundat Highway Pensacola, ion Pensacola FL--Jacksonv , FL ille JBR 32514 ------------------------------------------------------------------------ Monetary Arthriti 8383 North $1,000 11/13/2014 Arthritis s Davis Foundation, Foundat Highway Pensacola, ion Pensacola FL for , FL Pensacola 32514 JBR/W ------------------------------------------------------------------------ Monetary Arthriti 8383 North $1,500 11/13/2014 Arthritis s Davis Foundation, Foundat Highway Pensacola, ion Pensacola FL--Orlando , FL Jingle Bell 32514 Run & Walk ------------------------------------------------------------------------ Monetary Arthriti 111 South $2,500 4/18/2014 Walk to Cure s Independe Arthritis, Foundat nce Mall Philadelphia ion, E Suite , PA, May Inc. 500 17, 2014 Philadelp hia, PA 19106 ------------------------------------------------------------------------ Monetary Arthriti 115 NE $5,000 6/9/2014 Eight Walks s 100th to Cure Foundat Suite Arthritis in ion, #350 the Great Inc. Seattle, West Region WA 98125 ------------------------------------------------------------------------ Monetary Arthriti 122 East $50,000 4/4/2014 NE Region s 42nd Jingle Bell Foundat Street Runs 2014 ion, 18th Inc. Floor New York, NY 10168 ------------------------------------------------------------------------ Monetary Arthriti 1876 $3,500 4/4/2014 Arthritis s Minnehaha Foundation's Foundat Avenue 2014 Walks ion, West St. in MN, WI Inc. Paul, MN and ND 55104 ------------------------------------------------------------------------ Monetary Arthriti 209 10th $2,000 4/21/2014 Arthritis s Avenue Foundation Foundat South Walks to ion, Suite 228 Cure Inc. Nashville Arthritis in , TN TN and AL 37203 ------------------------------------------------------------------------ Monetary Arthriti 29 Crafts $3,500 4/21/2014 Walks to Cure s Street Arthritis in Foundat Suite 450 CT, RI, NH, ion, Newton, and MA Inc. MA 02458 ------------------------------------------------------------------------ Monetary Arthriti 35 East $12,000 4/21/2014 Walks to Cure s Wacker Arthritis in Foundat Drive IL, IN, IA, ion, Suite KS, MO, NE Inc. 2260 Chicago, IL 60601 ------------------------------------------------------------------------ Monetary Arthriti 400 $500 6/9/2014 2014 Walk to s Hibiscus Cure Foundat Street Arthritis, ion, West Palm Lake Worth, Inc. Beach, FL FL 33401 ------------------------------------------------------------------------ Monetary Arthriti 408 12th $500 4/18/2014 Walk to Cure s Street Arthrits, Foundat West Sarasota, ion, Bradenton FL, May 17, Inc. , FL 2014 34205 ------------------------------------------------------------------------ Monetary Arthriti 4300 $4,000 4/21/2014 South Central s McArthur Region Walks Foundat Suite 245 to Cure ion, Dallas, Arthritis Inc. TX 75209 ------------------------------------------------------------------------ Monetary Arthriti 4720 $10,000 4/18/2014 Arthritis s Montgomer Walks--Mid Foundat y Lane Atlantic ion, Suite 300 Region--DE, Inc. Bethesda, MD, DC, VA, MD 20814 NC, and SC. ------------------------------------------------------------------------ Monetary Arthriti 800 West $10,000 6/25/2014 Walks to Cure s 6th Arthritis in Foundat Street CA, AZ, and ion, Suite HI Inc. 1250 Los Angeles, CA 90017 ------------------------------------------------------------------------ Monetary Arthriti 8383 North $500 3/17/2014 2014 Walk to s Davis Cure Foundat Highway Arthritis ion, Pensacola Pensacola FL Inc. , FL 32514 ------------------------------------------------------------------------ Monetary Big 2875 York $300 6/24/2014 Janssen Cares Brother Road Volunteers s Big Jamison, Days--Commun Sisters PA 18929 ity Service at Big Brothers Big Sisters, Jamison, PA ------------------------------------------------------------------------ Monetary Bowmans 1635 River $300 8/29/2014 Bowman's Hill Hill Road New Wild Flower Wildflo Hope, PA Preserve, wer 18938 New Hope, PA Preserv (2014 JCVD) e ------------------------------------------------------------------------ Monetary Bringing 940 West $2,500 10/28/2014 Bringing Hope Hope Valley Home Inc., Home Road Wayne, PA Inc. Wayne, PA 19087 ------------------------------------------------------------------------ Monetary Cancer 121 Avenue $2,000 4/21/2014 Cancer Care's Care, of the 6th Annual Inc. Americas Healing 6th Floor Hearts New York, Family NY 10013 Bereavement Camp, Milford, PA ------------------------------------------------------------------------ Monetary Cancer 121 Avenue $10,000 4/21/2014 2014-2015 Care, of the Edition of Inc. Americas ``A Helping 6th Floor Hand: The New York, Resource NY 10013 Guide for People with Cancer.'' ------------------------------------------------------------------------ Monetary Cancer 200 Kirk $600 6/25/2014 Janssen Cares Support Road Volunteer Communi Warminste Days--commun ty r, PA ity service Gilda's 18974 at Gilda's Club Club June 24 Warmins and June 26, ter, PA 2014 ------------------------------------------------------------------------ Monetary Cancer 4100 $2,500 10/3/2014 Cancer Support Chamounix Support Communi Drive Community of ty of Philadelp Philadelphia Philade hia, PA , lphia 19131 Warminister, PA ------------------------------------------------------------------------ Monetary Children 34th and $5,000 10/3/2014 CHOP s Civic Philadelphia Hospita Center , PA Child l of Blvd. Life Program Philade Philadelp lphia hia, PA Foundat 19104- ion 4399 ------------------------------------------------------------------------ Monetary Chrohn's 386 Park $15,000 8/29/2014 Crohn's and and Avenue Colitis Colitis South Foundation, Foundat 17th New York, ion Floor New NY--Camp York, NY Oasis ------------------------------------------------------------------------ Monetary Communit 300B $20,000 10/15/2014 Community y Lawrence Volunteers Volunte Drive in Medicine, ers in West West Medicin Chester, Chester, PA e Inc. PA 19380 ------------------------------------------------------------------------ Monetary Crohns 116 Wilson $5,000 11/13/2014 Buds N Suds and Pike Benefit Colitis Circle Concert Foundat Brentwood Nashville, ion of , TN TN America 37027 ------------------------------------------------------------------------ Monetary Crohns 116 Wilson $5,000 11/13/2014 Donate A and Pike Photo Colitis Circle Awareness Foundat Brentwood Campaign at ion of , TN ACG Fall America 37027 2014 ------------------------------------------------------------------------ Monetary Crohns 386 Park $135,000 4/22/2014 Take Steps and Avenue Walks Colitis South Nationwide Foundat 17th ion of Floor New America York, NY ------------------------------------------------------------------------ Monetary Crohns 9 Lake $3,000 4/18/2014 CCFA 's Camp and Bellevue Oasis for Colitis Drive IBD Foundat Suite 203 Pediatric ion of Bellevue, Patients, America WA 98005 Longbranch, WA ------------------------------------------------------------------------ Monetary Crohn's 386 Park $5,000 8/29/2014 CCFA, NY, NY and Avenue (DDW Colitis South Awareness) Foundat 17th ion of Floor New America York, NY ------------------------------------------------------------------------ Monetary Delaware 215 South $3,000 9/10/2014 Delaware Valley 16th Valley Science Street, Science Council Philadelp Council, hia PA STEM 19102 Programs ------------------------------------------------------------------------ Monetary Delaware 215 South $21,300 4/4/2014 Delaware Valley 16th Valley Science Street, Science Fairs, Philadelp Fairs Tri- Inc. hia PA State 19102 Competition, Oaks, PA ------------------------------------------------------------------------ Monetary Educatio 454 Maple $5,000 10/3/2014 Education- n-Plus Terrace Plus Inc., Inc. Ardmore, Philadelphia PA , PA Read Now Program ------------------------------------------------------------------------ Monetary Franklin 222 North $10,000 10/3/2014 Franklin Institu 20th Institute, te Street Philadelphia Philadelp , PA hia, PA 19103 ------------------------------------------------------------------------ Monetary Girl 330 Manor $4,000 10/3/2014 Girl Scouts Scouts Road of Eastern of Miquon, PA, Miquon, Eastern PA 19444 PA Pennsyl vania Inc. ------------------------------------------------------------------------ Monetary Green 1368 $15,000 10/3/2014 Green Valleys Prizer Valleys, Assocat Road Pottstown, ion of Pottstown PA (EITC Southea , PA participant) stern 19465 Pennsyl vania ------------------------------------------------------------------------ Monetary Hatboro 440 South $300 9/4/2014 Hatboro Area Area York Road YMCA, YMCA Hatboro, Hatboro, PA PA 19040 (2014 Jansen Cares V.D.) ------------------------------------------------------------------------ Monetary Hatboro 229 $300 8/29/2014 Hatboro- Horsham Meetingho Horsham Educati use Road Educational onal Hatboro- Foundation, Foundat Horsham, Horsham, PA ion PA 19044 ------------------------------------------------------------------------ Monetary Hatboro 229 $25,000 8/29/2014 Hatboro- Horsham Meetingho Horsham Ed. Educati use Road Foundation onal Hatboro- (EITC), Foundat Horsham, Horsham, PA ion PA 19044 ------------------------------------------------------------------------ Monetary Impact 2979 $300 8/29/2014 JBI Impact Thrift Bethlehem Thrift Sortes Pike Sortes, Inc. Montgomer Inc., yville, Montgomeryvi PA lle, PA ------------------------------------------------------------------------ Monetary Integrat 532 $1,000 4/4/2014 2014 Belmont ed Broadholl Stakes Blue Medical ow Road Ribbon Run Foundat Suite for Prostate ion, 142A Cancer, Inc. Melville, Melville, NY NY 11747 ------------------------------------------------------------------------ Monetary Internat 6144 Clark $10,000 12/24/2014 International ional Center Waldenstroms Waldens Avenue Macroglobuli troms Sarasota, nemia Macrogl FL 34238 Foundation, obuline Sarasota, FL mia Foundat ion ------------------------------------------------------------------------ Monetary Junior 522 South $5,000 10/3/2014 Junior Achieve Walnut Achievement, ment of Street Wayne, PA Delawar Wilmingto (Horsham e n, DE Scools) Valley 19801 ------------------------------------------------------------------------ Monetary Leukemia 555 North $175,000 6/16/2014 LLS and Lane Nationwide Lympho Suite Light the Society 5010 Night Walks , Inc. Conshohoc ken, PA 19428 ------------------------------------------------------------------------ Monetary Metropol 2323 $15,000 10/3/2014 MANNA, itan Ranstead Philadelphia Area Street , PA Neighbo Philadelp rhood hia, PA Nurtrit 19103 ion Allianc e ------------------------------------------------------------------------ Monetary National PO Box 303 $2,500 8/29/2014 National Ovarian Holicong, Ovarian Cancer PA 18928 Cancer Coaliti Coalition on Inc. Inc., Holicong, PA ------------------------------------------------------------------------ Monetary National 6600 SW $50,000 11/13/2014 National Psorias 2nd Psoriasis is Avenue Foundation, Foundat Suite 300 Portland OR-- ion Portland, Compliments OR 97223 are Contagious ------------------------------------------------------------------------ Monetary Open 350 Main $300 8/29/2014 Royersford Door Street Outreach Royersfor Open Door d, PA (Janssen 19468 Cares V.D.), Royersford, PA ------------------------------------------------------------------------ Monetary Perkiome 1 West $300 8/29/2014 Perkioment n Skippack Watershed Watersh Pike Conservancy, ed Schwenksv Schwenksvill Conserv ille, PA e, PA ancy 19473 ------------------------------------------------------------------------ Monetary Philadel 325 $10,000 10/3/2014 Philadelphia phia Chestnut Reads, Inc., Reads, Street Philadelphia Inc. Philadelp , PA (EITC) hia, PA 19106 ------------------------------------------------------------------------ Monetary Premier PO Box 93 $5,000 10/3/2014 Premier Cares Cares Pleasant Foundation, Foundat Valley, Inc. ion NY 12569 Inc. ------------------------------------------------------------------------ Monetary Prostate 7009 S. $1,000 8/29/2014 Prostate Cancer Potomac Cancer Educati Street Education on Centennia Council, Council l, CO Centennial, 80112 CO ------------------------------------------------------------------------ Monetary Prostate 500 $10,000 4/21/2014 Prostate Health Victory Health Educati Road Education on Quincy, Network Network MA 02170 (PHEN) Sixth , Inc. Annual Father's Day Rally Nationwide ------------------------------------------------------------------------ Monetary Rebuidli PO Box $5,000 6/13/2014 Mantua Block ng 42752 Build, Togethe Philadelp Philadelphia r hia, PA , PA Philade 19101- lphia 2752 ------------------------------------------------------------------------ Monetary Retired 925 $7,000 10/15/2014 RSVP, Blue Senior Harvest Bell, PA Volunte Drive er Suite 100 Program Blue of Bell, PA Montgom 19422 ery County ------------------------------------------------------------------------ Monetary Riverben 1950 $5,000 6/9/2014 Outreach to d Spring Children/ Environ Mill Road Access to mental Gladwyne, Nature Educati PA 19035 Education on for local Center elementary school in Norristown, PA ------------------------------------------------------------------------ Monetary Special 2800 $4,000 12/31/2014 Special Equestr Street Equestrians, ians Road Warrington, Warringto PA n, PA 18976 ------------------------------------------------------------------------ Monetary The 34th $2,000 4/18/2014 5th Annual Childre Street Walk for ns Civic Hope, Hospita Center Veteran's l of Boulevard Park, Philade Philadelp Hamilton, lphia hia, PA NJ, Foundat 19104 benefitting ion IBD Research at CHOP ------------------------------------------------------------------------ Monetary The 4275 $3,000 6/9/2014 Hands-On Giving County Helping by Tree Line Road Children Suite 138 Chalfont, PA 18914 ------------------------------------------------------------------------ Monetary The 2600 $10,000 4/21/2014 Hubert J. P. Melmark Wayland Schoemaker Charita Road Classic, ble Berwyn, October 6, Foundat PA 19312 2014, ion Berwyn, PA ------------------------------------------------------------------------ Monetary Trustees University $7,000 10/15/2014 WXPN (Trutees of the of of the U of Univers Pennsylva PA), ity of nia Philadelphia Pennsyl Philadelp , PA vania hia, PA 19104 ------------------------------------------------------------------------ Monetary United 1709 $223,382 12/22/2014 United Way Way of Benjamin Campaign Greater Franklin Match Philade Parkway lphia Philadelp and hia, PA Souther 19103 n New Jersey ------------------------------------------------------------------------ Monetary Us Too 5003 $1,000 9/10/2014 Us Too Interna Fairview Internationa tional Ave. , Des Downers Plaines, IL Grove, IL 60515 ------------------------------------------------------------------------ Monetary Wissahic 12 Morris $2,603 6/25/2014 New kon Road wildflower Valley Ambler, meadow Watersh PA 19002 development ed via Janssen Associa Cares tion Volunteer Days. ------------------------------------------------------------------------ Monetary Wissahic 12 Morris $1,400 4/21/2014 Community kon Road Service Valley Ambler, Project for Watersh PA 19002 JBI's Bridge ed to Associa Employment tion, program; Inc. mentors and students planting trees and shrubs for water conservation at Wissahickon Valley Watershed ------------------------------------------------------------------------ Janssen has also made financial donations to independent charitable foundations that assist patients who are underinsured and in financial need with treatment-related expenses. In keeping with our donor agreements and applicable regulatory guidance, we will only disclose aggregate data on our charitable giving and do not publicize information on donations to specific foundations and disease states. In 2014, we contributed approximately $40 million in donations to independent charitable foundations, enabling them to provide assistance with medication-related copays to patients with cancer diseases. ---------------------------------------------------------------------------------------------------------------- ---------------------------------------------------------------------------------------------------------------- Product Johnson & Johnson One Johnson & $84,591,419 3/15/2013 Patient Assistance Patient Assistance Johnson Plaza, New Product Donation Foundation Brunswick, NJ 08933 ---------------------------------------------------------------------------------------------------------------- Product Johnson & Johnson One Johnson & $86,924,535 6/15/2013 Patient Assistance Patient Assistance Johnson Plaza, New Product Donation Foundation Brunswick, NJ 08933 ---------------------------------------------------------------------------------------------------------------- Product Johnson & Johnson One Johnson & $78,551,321 9/15/2013 Patient Assistance Patient Assistance Johnson Plaza, New Product Donation Foundation Brunswick, NJ 08933 ---------------------------------------------------------------------------------------------------------------- Product Johnson & Johnson One Johnson & $86,312,829 12/15/2013 Patient Assistance Patient Assistance Johnson Plaza, New Product Donation Foundation Brunswick, NJ 08933 ---------------------------------------------------------------------------------------------------------------- Updatd February 24, 2017 Janssen Pharmaceuticals, Inc. Monetary and Product Contributions to U.S.- based Charitable Organizations Full Year 2014 (Payments made from January 1, 2014 to December 31, 2014) ------------------------------------------------------------------------ Project Donation Payee Payee Payment Amount Payment Title/ Type Address (USD) Date Description ------------------------------------------------------------------------ Monetary 180 1 $1,000 9/22/2014 Youth Turnin Bethany Helpline g Road, Hunterdon, Lives Buildin Mercer, and Around g 3 Somerset , Inc. Suite Operations 42 Hazlet, NJ 07730 ------------------------------------------------------------------------ Monetary A P.O. Box $2,500 12/4/2014 A Woman's Woman' 299 Place s Doylest Prevention Place own, PA Project 18901 ------------------------------------------------------------------------ Monetary Adult 872 E $300 8/4/2014 Cost Day Main associated Center Street with 2014 of Bridgew Janssen Somers ater, Cares et NJ volunteer County 08807 activity ------------------------------------------------------------------------ Monetary Allies, 1262 $7,500 11/17/2014 Greensleeves Inc. Whiteho Flemington rse- Expansion Hamilto Environment n al Square Stewardship Road Program Buildin g A, Suite 101 Hamilto n, NJ 08690 ------------------------------------------------------------------------ Monetary America 100 West $5,000 5/27/2014 2014 EXPO n Station Pittsburgh Diabet Square es Drive Associ Suite ation 1900 Pittsbu rgh, PA 15219 ------------------------------------------------------------------------ Monetary America 1160 $30,000 12/10/2014 Diabetes n Route Interventio Diabet 22 East n Project es Suite ($20,000), Associ 103 and ation Bridege Community water, Outreach NJ Education 08807 ($10,000) ------------------------------------------------------------------------ Monetary America 1701 $125,000 12/10/2014 American n North Diabetes Diabet Beaureg Association es ard 's Outcomes- Associ Street based ation Alexand Community ria, VA Programs 22311 Targeted to High Risk Populations ------------------------------------------------------------------------ Monetary America 1 Union $5,000 10/16/2014 Fundraising n Street event Heart Suite support to Associ 301 benefit ation Robbins general ville, mission of NJ organizatio 08691 n. ------------------------------------------------------------------------ Monetary America 1000 $20,000 12/10/2014 Partnership n Wilson for Psychi Bouleva Workplace atric rd Mental Founda Suite Health ICU: tion 1825 Improving Arlingt Emotional on, VA Health 22208 ------------------------------------------------------------------------ Monetary America 1000 $100,000 12/10/2014 Typical or n Wilson Troubled? Psychi Bouleva Student atric rd Mental Founda Suite Health tion 1825 Education Arlingt Program on, VA 22208 ------------------------------------------------------------------------ Monetary America 1000 $225,000 12/10/2014 Campaign by n Wilson Psychiatris Psychi Bouleva ts and atric rd Judges to Founda Suite Reduce the tion 1825 Overreprese Arlingt ntation of on, VA Incarserate 22208 d Individuals with SMI ------------------------------------------------------------------------ Monetary America 707 $15,000 10/20/2014 Support for n Red Alexand the Cross er Road American Princet Red Cross on, NJ Disaster 08550 Cycle Services Program ------------------------------------------------------------------------ Monetary America Central $20,000 3/14/2014 Support to n Red New American Cross Jersey Red Cross 707 Disaster Alexand Relief er Road Services Suite 101 Princet on, NJ 08540- 6331 ------------------------------------------------------------------------ Monetary Anchor 482 $418 1/9/2014 General House, Centre Operating Inc. Street Support Trenton , NJ 08611 ------------------------------------------------------------------------ Monetary Anderso PO Box $17,500 10/22/2014 Integrated n 134 532 Care House County Management Rd. 523 Whiteho use, NJ 08889 ------------------------------------------------------------------------ Monetary Ann 595 West $9,500 12/4/2014 Ann Silver State Silverman man Street Community Commun Doylest Health ity own, PA Clinic for Health 18901 Bucks Clinic County residents ------------------------------------------------------------------------ Monetary Arc of 141 $5,000 9/22/2014 Fundraising Somers South event et Main support to County Street benefit Manvill general e, NJ mission of 08835 organizatio n ------------------------------------------------------------------------ Monetary Arc of 141 $4,000 10/1/2014 Respite Somers South Services et Main for County Street Families Manvill with e, NJ Children 08835 with Disabilitie s ------------------------------------------------------------------------ Monetary Arthrit 500 E. $1,500 7/1/2014 The is Morehea Community Servic d Arthritis/ es Street Diabetes Suite Project--ta 320 rgeting Charlot women with te, NC Type II 28202 Diabetes ------------------------------------------------------------------------ Monetary Asian 180 W $2,000 8/28/2014 Cardiovascul Health Washing ar Health Coalit ton Screenings ion Street for Low- Suite Income, 1000 Limited- Chicago English , IL Speaking At- 60602 Risk Diabetic Asian Immigrants and Refugees in Chicago ------------------------------------------------------------------------ Monetary Associa 819 $9,000 8/15/2014 Parital Care tion Alexand Rehabilitat for er Road ion and Advanc Princet Support ement on, NJ Services of 08540 Mental Health ------------------------------------------------------------------------ Monetary Associa 2400 N $20,000 11/17/2014 Spirit of tion Street the Heart: of NW Community Black Sutie Inverventio Cardio 249 n to logist Washing Improve s ton, DC Cardiovascu 20037 lar Health of Underserved Patients with AFIB ------------------------------------------------------------------------ Monetary Athens 7 N. $2,500 6/6/2014 The Mental Congres Gathering Health s St Place case , Inc. Athens, management OH services 45701 program for community drop-in center for adults with mental illness ------------------------------------------------------------------------ Monetary Autism 1060 $1,000 8/28/2014 Community Speaks State Partner Road 15th Annual 2nd Central New Floor Jersey Walk Princet Now for on, NJ Autism 08540 Speaks ------------------------------------------------------------------------ Monetary B More 5 East $5,000 8/15/2014 Support of Clubho Frankli B'More use, n Clubhouse Inc. Street which Baltimo offers re, MD members 21202 meaningful work, friendship, and links to stable housing, education and other resources ------------------------------------------------------------------------ Monetary Bay 66 Canal $5,000 6/12/2014 Bay Cove Cove Street Wellness Human Boston, Center to Servic MA assist es, 02114 diverse low- Inc. income clients who are working towards recovery from severe mental illness ------------------------------------------------------------------------ Monetary Bear 1162 $500 10/15/2014 Bear Tavern Tavern Bear Elementary Parent Tavern School s Road Science Associ Titusvi Fair ation lle, NJ 08560 ------------------------------------------------------------------------ Monetary Big 2875 $6,500 10/14/2014 School-Based Brothe York Mentoring rs Big Road Program Sister Jamison s of , PA Bucks 18929 County ------------------------------------------------------------------------ Monetary Big 2 West $7,500 10/1/2014 Big Brothers Brothe Washing Big Sisters rs Big ton Youth Sister Avenue Mentoring s Of Suite Program- Hunter 210 PO Somerset don Box 123 County Somers Washing et and ton, NJ Warren 07882 County ------------------------------------------------------------------------ Monetary Big 535 East $8,000 8/26/2014 Big Brothers Brothe Frankli Big Sisters rs Big n of Mercer Sister Street County s of Trenton Youth Mercer , NJ Mentoring County 08610 Program ------------------------------------------------------------------------ Monetary Boys 212 $22,500 10/14/2014 Career and Centre Launch Girls Street (Career Club Trenton Exploration of , NJ , Work Trento 08611 Readiness, n and HS Mercer Graduation, County and Career Pathway Program) ------------------------------------------------------------------------ Monetary Bridgeh 950 S. $4,000 6/12/2014 Recovery aven, First Connection Inc. Street program Louisvi lle, KY 40203 ------------------------------------------------------------------------ Monetary Bridgew 615 N. $5,000 12/4/2014 Self- ay Broad Sufficiency Rehabi Street Fund for litati Elizabe Somerset, on th, NJ Mercer and Servic 07208 Hunterdon es residents ------------------------------------------------------------------------ Monetary Bristol 120 $7,500 12/10/2014 ArtRageous Rivers Radclif Summer Camp ide fe Theate Street r Co, P O Box Inc. 1250 Bristol , PA 19007 ------------------------------------------------------------------------ Monetary Broward 305 $10,000 5/27/2014 Affordable County Southea Rental Commun st 18th Housing ity Court program Develo Fort pment Lauderd Corpor ale, FL ation 33316 , Inc. ------------------------------------------------------------------------ Monetary Bucks 1069 $5,000 11/17/2014 Bucks County County Jackson Housing Housin ville Group's g Road Veterans Group Ivyland Housing , PA Assistance 18974 Program ------------------------------------------------------------------------ Monetary Catholi Diocese $5,000 7/1/2014 On My Own-- c of Supportive Charit Trenton Housing ies Delawar Program e House Services Mental program Health Service s 25 Ikea Drive Westham pton, NJ 08060 ------------------------------------------------------------------------ Monetary Catholi Diocese $17,500 7/7/2014 Partners In c of Recovery Charit Trenton program ies Delawar e House Mental Health Service s 25 Ikea Drive Westham pton, NJ 08060 ------------------------------------------------------------------------ Monetary Catholi 212 $75 1/28/2014 Employee c Ninth directed Charit Street donation in ies Pittsbu lieu of Dioces rgh, company e of Pennsyl holiday Pittsb vania gift urgh 15222 ------------------------------------------------------------------------ Monetary Catholi 212 $75 12/3/2014 Employee c Ninth directed Charit Street donation in ies Pittsbu lieu of Dioces rgh, company e of Pennsyl holiday Pittsb vania gift urgh 15222 ------------------------------------------------------------------------ Monetary Catholi 920 $4,000 10/16/2014 CYO's Broad c South St. Trenton Youth Broad Center Organi Street After zation Trenton School of , NJ Program's Mercer 08611 (ASP) County Tutoring Project ------------------------------------------------------------------------ Monetary Center 11 $300 8/4/2014 Cost for Minneak associated Educat oning with 2014 ional Road Janssen Advanc Fleming Cares ement ton, NJ volunteer 08822 activity ------------------------------------------------------------------------ Monetary Center 11 $15,000 10/20/2014 Employment for Minneak Training Educat oning program ional Road enhancement Advanc Fleming s ement ton, NJ 08822 ------------------------------------------------------------------------ Monetary Center Harzfeld $10,000 9/16/2014 PAINS: for Buildin National Practi g 1111 Pain cal Main Strategy Bioeth Street, Roll-Out ics Suite Meeting 500 Kansas City, MO 64105-2 116 ------------------------------------------------------------------------ Monetary Chabad PO Box $1,000 5/9/2014 ``We Care'' Lubavi 29 Educational tch of Princet Series Mercer on, NJ County 08542 , Inc. ------------------------------------------------------------------------ Monetary Child 204 N. $2,000 10/1/2014 Adolescent Home West Prenatal and Street and Commun #101 Parenting ity Doylest Continuum own, PA 18901 ------------------------------------------------------------------------ Monetary Childre 635 $10,000 10/20/2014 CUNA and n's South Body and Home Clinton Soul Societ Avenue Prenatal y of Trenton Health New , NJ Education Jersey 08611 Program ------------------------------------------------------------------------ Monetary Childre Roebling $5,000 5/7/2014 Fundraising n's Market event Home Complex support to Societ 635 benefit y of South general New Clinton mission of Jersey Avenue organizatio Trenton n , NJ 08611- 1831 ------------------------------------------------------------------------ Monetary Christi PO Box $2,500 12/3/2014 Pajama Bags nes 190 for Kids in Hope Hopewel Need in for l, NJ Mercer Kids 08525 County Founda tion ------------------------------------------------------------------------ Monetary College 2000 $22,500 10/14/2014 Nursing of New Penning Merit Jersey ton Scholarship Road s ($10,000) P.O. and Box Educational 7718 Opportunity Ewing, Fund NJ Promise 08628 Awards ($12,500) ------------------------------------------------------------------------ Monetary Colorad PO Box $2,500 8/1/2014 Peer o 6336 Workforce Mental Denver, Initiative Wellne CO ss 80206 Networ k ------------------------------------------------------------------------ Monetary Communi PO Box $5,000 11/17/2014 Rise Summer ty 88 116 Healthy Action North Food Servic Main Initiative e Street for low Center Hightst income , Inc. own, NJ youth 08520 ------------------------------------------------------------------------ Monetary Communi 4059 $5,000 10/23/2014 Arts for ty Skyron Seniors Conser Drive ($3,000) vatory Doylest and Music of own, PA Therapy Music 18902 ($2,000) ------------------------------------------------------------------------ Monetary Communi PO Box $150,000 12/12/2014 Johnson & ty 338 Johnson Founda Morrist Somerset tion own, NJ County of New 07963 Contributio Jersey ns Fund to support healthcare and basic needs of residents in Somerset and Hunterdon Counties ------------------------------------------------------------------------ Monetary Communi P.O. Box $11,500 10/13/2014 Each One, ty 15176 Teach One: Health 407 An Evidence Coalit Crutchf Based ion, ield Diabetes Inc. Street Self- Durham, Management NC Workshop 27704 and Community Leaders Training ------------------------------------------------------------------------ Monetary Communi 199 $12,000 5/27/2014 Pathway to ty Pomeroy Recovery Hope, Road residential Inc. Parsipp programs any, NJ ($10,000) 07054 and The Mental Health Educational Forum and Wellness Fair ($2,000) ------------------------------------------------------------------------ Monetary Communi 199 $13,000 11/5/2014 Hope for ty Pomeroy Veterans Hope, Road and Valley Inc. Parsipp Brook any, NJ Village for 07054 Veterans ------------------------------------------------------------------------ Monetary Communi 310 W. $7,500 10/20/2014 Social ty State Security Justic Street Services e 3rd and Center Floor Veterans , Inc. Trenton Assistance , NJ Project 08618 ------------------------------------------------------------------------ Monetary Communi 507 E. $4,000 7/1/2014 Compeer ty College Program of Mental Street Johnson Health Iowa County Center City, For IA Mid- 52240 Easter n Iowa dba Compee r Progra m, Inc. ------------------------------------------------------------------------ Monetary Compeer 259 $2,500 7/29/2014 Compeer Roches Monroe Rochester ter, Avenue Youth and Inc. Rochest Family er, NY Mentoring 14607 Program ------------------------------------------------------------------------ Monetary Compeer 259 $3,000 7/1/2014 Compeer , Inc. Monroe Senior Avenue Partners Suite program 340 Rochest er, NY 14607 ------------------------------------------------------------------------ Monetary Contact 60 S. $8,500 12/4/2014 CRISIS of Main HOTLINES Mercer Street and Online County Penning Emotional New ton, NJ Support: Jersey 08534 CRISIS CHAT , Inc. and TxtToday ------------------------------------------------------------------------ Monetary Contact 60 South $1,000 3/17/2014 Annual of Main Senior Mercer Street Volunteer County Penning Recognition New ton, NJ Brunch, Jersey 08534 ``Volunteer , Inc. s Are Heroes!'' ------------------------------------------------------------------------ Monetary Court 1450 $12,500 10/14/2014 CASA of Appoin Parksid Mercer ted e Child Specia Avenue Advocacy l Suite Program for Advoca 22 Abused and tes Ewing, Neglected NJ Children 08638 ------------------------------------------------------------------------ Monetary D&R P.O. Box $250 2/3/2014 23rd Annual Canal 2 Rocky D&R Canal Watch Hill, Watch 5K NJ Fun Run 08553 ------------------------------------------------------------------------ Monetary Deborah 212 $1,000 8/28/2014 2015 Women's Hospit Trenton Heart al Road Health Founda Browns Symposium tion Mills, NJ 08015 ------------------------------------------------------------------------ Monetary Delawar 14 $300 8/4/2014 Cost e Michael associated River McCorri with 2014 Steamb stin Janssen oat Road Cares Floati Hamilto volunteer ng n, NJ activity Classr 08690 oom, Inc. ------------------------------------------------------------------------ Monetary Delawar 14 $4,000 11/3/2014 Environmenta e Michael l education River McCorri for Steamb stin underfunded oat Road and Floati Hamilto underserved ng n, NJ schools and Classr 08690 youth oom, groups Inc. ------------------------------------------------------------------------ Monetary Depress 5 $1,000 3/17/2014 DBSA NJ ion Village Mutual Aid and Court Support Bipola Lawrenc Group r eville, Facilitator Suppor NJ Training t 08648 Allian ce ------------------------------------------------------------------------ Monetary Detroit 10 $5,000 8/25/2014 Managing Centra Peterbo SPMI and l City ro Chronic Commun Profess Disease ity ional Mental Buildin Health g , Inc. 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$7,500 3/17/2014 Education l North briefing, Blood Washing ``So You Clot ton Think You Allian Street Can't Get A ce Suite Blood Clot? 328 B Think Rockvil Again!'' le, MD 20850 ------------------------------------------------------------------------ Monetary Nationa 1701 K $20,000 12/10/2014 Prescription l Street Drug Abuse Counci NW, and Pain l for Suite Management Behavi 400 Initiative oral Washing Health ton, DC 20006 ------------------------------------------------------------------------ Monetary Nationa 1701 K $60,000 12/10/2014 Same Day l Street Access Counci NW, Initiative l for Suite Behavi 400 oral Washing Health ton, DC 20006 ------------------------------------------------------------------------ Monetary Nationa 1701 K $35,000 12/10/2014 Early Onset l Street Psychosis Counci NW, Initiative l for Suite Behavi 400 oral Washing Health ton, DC 20006 ------------------------------------------------------------------------ Monetary Nationa 1701 K $50,000 12/10/2014 Health l Street Justice Counci NW, Learning l for Suite Initiative Behavi 400 oral Washing Health ton, DC 20006 ------------------------------------------------------------------------ Monetary Nationa 1701 K $75,000 12/10/2014 2015 Policy l Street Action Counci NW, Center l for Suite Behavi 400 oral Washing Health ton, DC 20006 ------------------------------------------------------------------------ Monetary Nationa 1701 K $30,000 12/10/2014 Leadership l Street Development Counci NW, Initiatives l for Suite Behavi 400 oral Washing Health ton, DC 20006 ------------------------------------------------------------------------ Monetary Nationa 949 W. $16,500 12/3/2014 Academic l State Creative Junior Street Engagement Tennis Trenton Program and , NJ ($6,500.00) Learni 08618 , ng of Benefactor Trento sponsor n 2015 Annual Gala ($10,000.00 ) ------------------------------------------------------------------------ Monetary Nationa 9707 E $10,000 11/19/2014 Patient l Easter Navigator Stroke Lane, Program / Associ Suite B Stroke ation Centenn Recovery ial, CO Navigator 80112 ------------------------------------------------------------------------ Monetary Nationa 9707 E $62,290 11/19/2014 Web-based l Easter health Stroke Lane, game, Associ Suite B ``Stroke ation Centenn and ial, CO Nonvalvular 80112 Atrial Fibrillatio n: Beating Your Odds'' ------------------------------------------------------------------------ Monetary New 444 W. $6,000 3/17/2014 Support Founda Frontag Health and tion e Road Wellness Center Northfi Program, eld, IL benefitting 60093-- clients who 3009 are managing a co-morbid diagnosis ------------------------------------------------------------------------ Monetary New 275 Rt. $4,000 3/17/2014 New Jersey Jersey 10 Parent's Parent East, Caucus s Suite Outreach RV Caucus 220-414 Tour and Succasu Professiona nna, NJ l Parent 07876 Advocacy Training Program ------------------------------------------------------------------------ Monetary NewBrid PO Box $2,000 7/1/2014 Day ge 336 (7 Treatment Servic Industr Program for es, ial Adults Inc. Road, Pequann ock, NJ 07440) Pompton Plains, NJ 07444 ------------------------------------------------------------------------ Monetary NHS 620 E. $5,000 5/27/2014 Hollywood Human Germant Beauty Servic own Salon es Pike Documentary Founda Lafayet Project--po tion te st Inc Hill, production PA costs 19444 ------------------------------------------------------------------------ Monetary Northea 334 $2,500 8/26/2014 Healthy Food st River for Healthy Organi Road Communities c Hillsbo Farmin rough, g NJ Associ 08844 ation of NJ ------------------------------------------------------------------------ Monetary Notre 1835 $100 8/18/2014 Memorial Dame Catasau donation of qua Bethle Road hem Bethleh School em, PA 18018 ------------------------------------------------------------------------ Monetary Oldies PO Box $75 3/17/2014 Employee But 361 directed Goodie Newingt donation in s on, VA lieu of Cocker 22122 company Rescue holiday , Inc. gift ------------------------------------------------------------------------ Monetary One 1977 $3,500 11/17/2014 Wish Simple North Program: Wish Olden Education Ave, Fund for #292 Aging Out Trenton Youth , NJ 08618 ------------------------------------------------------------------------ Monetary Open 14 Lake $2,000 7/18/2014 Support to Road Court provide the Fleming homebound ton, NJ elderly and 08822 people with disabilitie s or mental illness with stimulating and enriching activities that would otherwise be unavailable to them ------------------------------------------------------------------------ Monetary Our 2626 E $100 8/4/2014 Memorial Hospic 17th Donation e of Street South Columbu Centra s, IN l 47201 Indian a ------------------------------------------------------------------------ Monetary Passage 211 $5,000 12/15/2014 The State Theatr Mercer Street e Street Project Compan PO Box y Inc. 967 Trenton , NJ 08611 ------------------------------------------------------------------------ Monetary PEI 231 $300 8/4/2014 Cost Kids Lawrenc associated e Road with 2014 Lawrenc Janssen eville, Cares NJ volunteer 08648 activity ------------------------------------------------------------------------ Monetary PEI 231 $17,500 10/14/2014 Comprehensiv Kids Lawrenc e Juvenile e Road Offenders Lawrenc Outreach eville, Services NJ (CJOOS) 08648 program ------------------------------------------------------------------------ Monetary Penning PO Box $1,000 5/30/2014 Fundrasining ton 628 event Day, Penning support to Inc. ton, NJ benefit 08534 general mission of organizatio n ------------------------------------------------------------------------ Monetary People 140 East $2,500 10/22/2014 People and And Hanover Stories Storie Street with Mercer s--Gen Trenton County te Y , NJ Seniors Cuento 08608 s Inc. ------------------------------------------------------------------------ Monetary Planned PO Box $4,000 7/1/2014 Whole-Health Living 4755 and Assist Austin, Wellness ance TX Program Networ 78765 k of Centra l Texas ------------------------------------------------------------------------ Monetary Planned 13151 $2,500 8/26/2014 Education Living Emily and Social Assist Road, Skills ance Suite Development Networ 240 Program k of Dallas, North TX Texas, 75240 Inc. ------------------------------------------------------------------------ Monetary Plansma 118 West $3,500 9/16/2014 2014 rt NJ State Corporate Trenton membership , NJ renewal 08608 donation to support efforts around sound land use planning ------------------------------------------------------------------------ Monetary Princet 15 $25,000 12/12/2014 Path to on Princes Impact--Cap Area s Road acity Commun Lawrenc Building ity eville, Program Founda NJ tion, 08648 Inc. ------------------------------------------------------------------------ Monetary Princet 123 E. $15,000 11/17/2014 Hunger on Hanover Prevention Outrea St. and ch Trenton Nutrition Projec , NJ Education ts / 08608 ($10,000) Crisis and Housing Minist Stability ry of Services Mercer ($5,000) County ------------------------------------------------------------------------ Monetary Princet 45 $2,500 10/29/2014 Living on Stockto Healthy for Senior n St Older Resour Princet Adults ce on, NJ Center 08540 ------------------------------------------------------------------------ Monetary Princet 350 $10,000 9/22/2014 United on- Alexand Leaders of Blairs er Road Tomorrow town Princet (ULOT) at Center on, NJ Trenton Inc. 08540 Central High School- West Campus ------------------------------------------------------------------------ Monetary Printma 440 $5,000 10/20/2014 Roving Press king River Center Road of New Branchb Jersey urg, NJ 08876 ------------------------------------------------------------------------ Monetary Printma 440 $15,000 10/20/2014 Combat Paper king River NJ Center Road of New Branchb Jersey urg, NJ 08876 ------------------------------------------------------------------------ Monetary Project 1515 $5,000 7/18/2014 Mental HOME Fairmou Health/ nt Recovery Avenue Treatment Philade Services lphia, for Adults PA Who Have 19130 Experienced Homelessnes s ------------------------------------------------------------------------ Monetary Raritan P.O. Box $8,000 11/17/2014 WaterWays Headwa 273 Environment ters Gladsto al Associ ne, NJ Education ation 07934 Program ------------------------------------------------------------------------ Monetary Raritan 118 $20,000 11/5/2014 Promoting Valley Lamingt Access to Commun on Road STEM and ity Branchb Nursing Colleg urg, NJ Education e 08876 at Raritan Founda Valley tion Community College: Nursing Scholarship s ($10,000), Galileo Scholarship s ($5,000), Textbooks ($2,500), STEM Institute ($2,500) ------------------------------------------------------------------------ Monetary Regions 640 $5,000 5/9/2014 Mental Hospit Jackson Health Drug al Street Assistance Founda St. Program tion Paul, MN 55101 ------------------------------------------------------------------------ Monetary Regions 640 $12,500 5/9/2014 Make It OK Hospit Jackson Campaign to al Street fight Founda St. stigma tion Paul, MN 55101 ------------------------------------------------------------------------ Monetary Rescue 98 $25,000 9/22/2014 Emergency Missio Carroll Services n of Street, program Trento PO Box n 790 Trenton , NJ 08605 ------------------------------------------------------------------------ Monetary Resourc 427 $300 8/4/2014 Cost e Homeste associated Center ad Road with 2014 Of Hillsbo Janssen Somers rough, Cares et, NJ volunteer Inc 08844 activity ------------------------------------------------------------------------ Monetary Rider 2083 $20,000 11/5/2014 Urban STEM Univer Lawrenc ($10,000), sity eville Janssen Road Science and Lawrenc Business eville, Scholarship NJ s ($7,500), 08648 Environment al Symposium ($2,500) ------------------------------------------------------------------------ Monetary Riverbe PO Box $5,000 7/1/2014 In-SHAPE nd 2032 Program Commun Concord ity , NH Mental 03302- Health 2032 Inc ------------------------------------------------------------------------ Monetary Riversi 4 South $7,500 10/20/2014 Riverside de Union Symphonia Sympho Street Senior nia P.O. Outreach Inc Box 650 Program Lambert ville, NJ 08530 ------------------------------------------------------------------------ Monetary San 2789 $5,000 5/27/2014 San Franci 25th Francisco sco Street Collaborati Genera Suite ve Court's l 2028 PO Behavioral Hospit Box Health al 410836 Court--Supp Founda San orted tion Francis Employment co, CA and 94110 Motivationa l Incentives Program ------------------------------------------------------------------------ Monetary Schizop PO Box $2,500 8/15/2014 2014 hrenia 941222 National And Houston Conference, Relate , TX ``Call to d 77094- Action: Disord 8222 Shattering ers Stigma'' Allian ce Of Americ a ------------------------------------------------------------------------ Monetary SERV 20 $5,000 5/27/2014 12th Annual Founda Scotch SERV tion, Road Recovery NJ Inc. Ewing, conference NJ 08628 ------------------------------------------------------------------------ Monetary SERV 20 $5,000 5/27/2014 SERV Founda Scotch Foundation tion, Road Scholarship Inc. Ewing, Fund NJ 08628 ------------------------------------------------------------------------ Monetary Shannon PO Box $500 8/28/2014 Donation in Daley 1271 36 lieu of Memori Indian event al Run sponsorship Fund Whiteho to help use local area Station residents , NJ battling 08889 serious ailments and their families facing hardship ------------------------------------------------------------------------ Monetary Sharing 1920 $2,000 7/31/2014 Art program Place 10th at the 1920 Inc Avenue Club South P.O. Box 55945 Birming ham, AL 35255 ------------------------------------------------------------------------ Monetary Sisters 1201 $1,000 2/3/2014 Blue Ribbon Networ Hamilto sponsor k of n 2014 Health Centra Street Summit and l New Somerse Breakfast Jersey t, NJ 08873 ------------------------------------------------------------------------ Monetary Sisters 1201 $5,000 8/28/2014 Fundraising Networ Hamilto event k of n support to Centra Street benefit l New Somerse general Jersey t, NJ mission of 08873 organizatio n ------------------------------------------------------------------------ Monetary Somerse PO Box $100 11/12/2014 Memorial t 3000 donation County Somervi Office lle, NJ on 08876- Aging 1262 ------------------------------------------------------------------------ Monetary Somerse 49 $680 2/3/2014 General t Home Brahma Operating for Avenue Support Tempor Bridgew arily ater, Displa NJ ced 08807 Childr en ------------------------------------------------------------------------ Monetary Somerse 49 $7,500 10/20/2014 Street t Home Brahma Smart--HIV for Avenue Prevention Tempor Bridgew program arily ater, within Displa NJ Somerset ced 08807 county Childr en ------------------------------------------------------------------------ Monetary St. 501 St $100 1/14/2014 Memorial Jude's Jude Donation Childr Place en's Memphis Resear , TN ch 38105 Hospit al ------------------------------------------------------------------------ Monetary St. One $15,000 10/20/2014 Providing Mary Summit Food for Medica Square, School-Age l Suite Children Center 300 Living in Founda 1717 Poverty: tion Langhor The St. ne- Mary Newtown Backpacks Road for Kids Langhor Program ne, PA 19047 ------------------------------------------------------------------------ Monetary Stony 31 Titus $15,000 11/5/2014 StreamWatch: Brook Mill Science in Millst Road the Service one Penning of Waters ton, NJ Conservatio hed 08534 n Associ ation ------------------------------------------------------------------------ Monetary SWIM 120 $2,000 9/22/2014 Program Inc. Findern Development e Project in Avenue Somerset Bridgew and ater, Hunterdon NJ Counties--V 08807 olunteer Training in aquatic exercise for the disabled, administrat ive training for coordinator s and co- coordinator s, and sensitivity training ------------------------------------------------------------------------ Monetary TASK, 72\1/2\ $25,000 10/14/2014 TASK Meal Inc. Escher Service Street, Program P.O. Box 872 Trenton , NJ 08605 ------------------------------------------------------------------------ Monetary The Paul $9,500 10/1/2014 Arts Council Arts Robeson of Counci Center Princeton l of for the Community Prince Arts Outreach ton 102 programs Withers for youth poon and seniors Street Princet on, NJ 08542 ------------------------------------------------------------------------ Monetary The 2020 $2,000 11/17/2014 Art for Center Burnt Special for Mills Needs Contem Road Children porary Bedmins Art ter, NJ 07921 ------------------------------------------------------------------------ Monetary The 19 $13,500 9/22/2014 Clinically- Center Dellwoo managed, For d Lane residential Great Somerse treatment Expect t, NJ program for ations 08873 homeless, pregnant/ parenting adult women in substance use recovery, and their children ($10,000), Annual Gala ($3,500) ------------------------------------------------------------------------ Monetary The 1040 $5,000 7/1/2014 Jail Edinbu Waltham Diversion rg Street Program Center Lexingt on, MA 02421- 8033 ------------------------------------------------------------------------ Monetary The 8150 N. $40,000 11/17/2014 HeartGuide-- Mended Central Patient Hearts Express Resource , Inc. way, and Suite Visiting M2248 Program Dallas, TX 75206 ------------------------------------------------------------------------ Monetary The 401 $500 1/14/2014 Flash Lite Mental Cypress sponsor Health Street 2014 Lite Center Manches Up The Nite Of ter, NH Run/Walk Greate 03103 for Mental r Health 5k Manche ster ------------------------------------------------------------------------ Monetary The 400 $300 8/26/2014 Costs Pennsb Pennsbu associated ury ry with 2014 Societ Memoria Janssen y l Road Cares Morrisv volunteer ille, activity PA 19067 ------------------------------------------------------------------------ Monetary The P.O. Box $5,000 12/3/2014 The Prince 2063 Princeton ton Princet Festival Festiv on, NJ Intergenera al 08543 tional Opera Workshop for Teens and their Families ------------------------------------------------------------------------ Monetary Thomas 101 West $10,000 11/5/2014 Scholarships Edison State for Nursing State Street Students Colleg Trenton Enrolled in e , NJ Thomas Founda 08608 Edison tion State College's Accelerated Second Degree BSN Program. ------------------------------------------------------------------------ Monetary Trenton PO Box $1,500 9/22/2014 Financial Commun 5206 Aid to ity Trenton subsidize Music , NJ tuition School 08638 costs for families qualifying based on family size and income-- music instruction s for students ------------------------------------------------------------------------ Monetary Trenton 635 $3,500 11/17/2014 Trenton Educat South Education ion Clinton Dance Dance Avenue Institute Instit Trenton program for ute , NJ at-risk 08611 youth in Trenton ------------------------------------------------------------------------ Monetary Trenton 218 N $10,000 10/23/2014 Inroads for Health Broad Health: Team St Taking it Inc Trenton to the , NJ Streets 08608 ------------------------------------------------------------------------ Monetary Trinity 22 $9,000 11/17/2014 Mental Counse Stockto Health and ling n Wellness Servic Street Programs es Trinity Counsel ing Service Princet on, NJ 08540 ------------------------------------------------------------------------ Monetary Truist/ Departme $32,261 12/12/2014 Truist Fronts nt processing tream, CH16952 fee for Inc. Palatin total 2014 e, IL United Way 60055- Campaign 6952 (fee associated with NJ companies) ------------------------------------------------------------------------ Monetary Twiligh P.O. Box $5,000 11/17/2014 Simple Needs t Wish 1042 11 Wish Founda Duane Granting tion Road Program Doylest Expansion own, PA 18901 ------------------------------------------------------------------------ Monetary UIH 4 North $7,500 10/14/2014 Community of Family Broad Health for Partne Street Men rs 2nd Floor Trenton , NJ 08618- 4408 ------------------------------------------------------------------------ Monetary United 9-25 $9,000 8/26/2014 Princeton Negro Alling Committee Colleg St. of UNCF e Fund Second Scholarship Floor -Scholarshi Newark, p support NJ for 07102 deserving STEM students in Mercer or Somerset Counties ------------------------------------------------------------------------ Monetary United P.O. Box $607,875 12/12/2014 Company Way 418607 match to Worldw Boston, employee ide MA United Way 02241- campaign 8607 for NJ based commercial companies of Janssen Pharmaceuti cal Companies of Johnson & Johnson less Truist processing fee ------------------------------------------------------------------------ Monetary US Pain 670 $7,500 12/4/2014 INvisible Founda newfiel Project tion d street suite b middlet own, CT 06457 ------------------------------------------------------------------------ Monetary Valeo 5401 SW $5,000 7/18/2014 Services for Behavi 7th Employment oral Street Success Health Topeka, Program Care KS serving Inc 66606 consumers with Schizophren ia and other severe mental illness ------------------------------------------------------------------------ Monetary Volunte P.O. Box $8,500 10/1/2014 SkillsConnec er 615 t skills Connec Princet based t on, NJ community 08542 volunteer program ------------------------------------------------------------------------ Monetary West 120 $2,000 7/1/2014 Young Adults Bergen Chestnu with Mental t Schizophren Health Street ia Young care Ridgewo Adult Track od, NJ of the 07450- Partial 2500 Care Program ------------------------------------------------------------------------ Monetary West 120 $300 8/4/2014 Cost Bergen Chestnu associated Mental t with 2014 Health Street Janssen care Ridgewo Cares od, NJ Volunteer 07450- Activity 2500 ------------------------------------------------------------------------ Monetary West PO Box $5,000 9/22/2014 STEM Windso 280 Excellence r West in Plains Windsor Education boro , NJ Grant Educat 08550- Program ion 0280 Founda tion ------------------------------------------------------------------------ Monetary Womansp 1530 $2,500 10/20/2014 Emergency ace Brunswi Domestic ck Violence Avenue Shelter Lawrenc program eville, NJ 08648 ------------------------------------------------------------------------ Monetary Wounded 4899 $100 5/16/2014 Memorial Warrio Belfort Donation r Road Projec Suite t 300 Jackson ville, FL 32256 ------------------------------------------------------------------------ Monetary Wounded 4899 $75 12/3/2014 Employee Warrio Belfort directed r Road donation in Projec Suite lieu of t 300 company Jackson holiday ville, gift FL 32256 ------------------------------------------------------------------------ Monetary YMCA of 431 $7,500 12/10/2014 The YMCA of Trento Penning Trenton's n ton Stars of Avenue Science Trenton Program , NJ 08618 ------------------------------------------------------------------------ Monetary Young 349 W. $3,500 10/20/2014 College Schola State Preparatory rs' St Program Instit Trenton ute , NJ 08618 ------------------------------------------------------------------------ Monetary YWCA 59 Paul $3,000 11/17/2014 Breast Prince Robeson Cancer ton Place Resource Princet Center--Wom on, NJ en of 08540 Wisdom (WOW) Program ------------------------------------------------------------------------ Product AmeriCa 88 $490,904 3/19/2014 Product res Hamilto Donation Founda n for tion Avenue Humanitaria Stamfor n Relief in d, CT the U.S., 06902 El Salvador, Guatemala, Honduras, Nicaragua, Cambodia, Pakistan, and Peru. ------------------------------------------------------------------------ Product AmeriCa 88 $834,365 3/19/2014 Product res Hamilto Donation Founda n for tion Avenue Humanitaria Stamfor n Relief in d, CT Guatemala, 06902 El Salvador, Honduras, Nicaragua. ------------------------------------------------------------------------ Product AmeriCa 88 $383,214 10/23/2014 Product res Hamilto Donation in Founda n Ave support of tion Stamfor Disaster d, CT Response 06902 ------------------------------------------------------------------------ Product AmeriCa 88 $233,871 12/3/2014 Product res Hamilto donation Founda n Ave for tion Stamfor humanitaria d, CT n 06902 assistance in Malawi, Tanzania, West Bank, Armenia, Dominican Republic, El Salvador, Guatemala, Nicaragua, Peru, Tanzania ------------------------------------------------------------------------ Product AmeriCa 88 $100,985 12/3/2014 Product res Hamilto donation Founda n Ave for tion Stamfor humanitaria d, CT n 06902 assistance in Malawi, Tanzania, Armenia, Dominican Republic, Colombia ------------------------------------------------------------------------ Product AmeriCa 88 $825,981 11/6/2014 Product res Hamilto Donations Founda n Ave for tion Stamfor Humanitaria d, CT n Aid for 06902 Armenia, Dominican Republic, Gaza, Pakistan, West Bank and Tanzania. ------------------------------------------------------------------------ Product AmeriCa 88 $2,389,565 8/4/2014 Product res Hamilto Donation in Founda n Ave support of tion Stamfor Humanitan d, CT Aid for the 06902 U.S., Afghanistan , Bangladesh, Pakistan, and Peru. ------------------------------------------------------------------------ Product Catholi 33-01 $5,279 12/3/2014 Pharmaceutic c Elevent al Product Medica h Donation l Street for Missio Long Humanitaria n Island n Aid in Board City, Haiti NY ------------------------------------------------------------------------ Product Direct 27 S. La $665,263 3/19/2014 Product Relief Patera Donation to Intern Lane support ationa Santa Humanitaria l Barbara n Relief in , CA Haiti, 93117 Dominican Republic, Honduras, Paraguay, and Nicaragua. ------------------------------------------------------------------------ Product Direct 27 S. La $614,185 3/19/2014 Product Relief Patera Donation to Intern Lane support ationa Santa Humanitaria l Barbara n Relief in , CA Haiti, 93117 Dominican Republic, and Paraguay. ------------------------------------------------------------------------ Product Direct 27 S. La $116,610 2/27/2014 Humanitarian Relief Patera Aid for Intern Lane Obstetric ationa Santa Fistula l Barbara program. , CA 93117 ------------------------------------------------------------------------ Product Direct 27 S. La $322,359 11/6/2014 Humanitarian Relief Patera Aid for Intern Lane Ghana, ationa Santa Paraguay, l Barbara and Peru. , CA 93117 ------------------------------------------------------------------------ Product Direct 27 S. La $2,354,643 12/3/2014 Pharmaceutic Relief Patera al Product Intern Lane Donation ationa Santa for l Barbara Disaster , CA Response 93117 and/or Humanitaria n Aid in Dominican Republic, Guatemala, Nicaragua, Peru, Panama, Paraguay and United States ------------------------------------------------------------------------ Product Direct 27 S. La $30,164 12/3/2014 Pharmaceutic Relief Patera al Product Intern Lane Donation ationa Santa for l Barbara Humanitaria , CA n Aid in 93117 Nicaragua, Peru ------------------------------------------------------------------------ Product Direct 27 S. La $2,093,905 8/5/2014 Humanitarian Relief Patera Aid for Intern Lane Haiti, ationa Santa Paraguay, l Barbara and U.S. , CA 93117 ------------------------------------------------------------------------ Product Heart 1021 $72,493 3/19/2014 Product to Pacific Donation Heart Avenue for Intern Kansas Humanitaria ationa City, n Relief in l KS Papua New 66102 Guinea and Cameroon. ------------------------------------------------------------------------ Product Heart 1021 $33,156 12/18/2014 Pharmaceutic to Pacific al Product Heart Avenue donation Intern Kansas for Ebola ationa City, Treatment l KS Unit in 66102 Liberia ------------------------------------------------------------------------ Product Heart 1021 $46,435 12/3/2014 Pharmaceutic to Pacific al Product Heart Avenue donation Intern Kansas for ationa City, humanitaria l KS n relief in 66102 Papua New Guinea ------------------------------------------------------------------------ Product Johnson One $380,566,479 3/15/2014 Patient & Johnson Assistance Johnso & Product n Johnson Donation Patien Plaza t New Assist Brunswi ance ck, NJ Founda 08933 tion ------------------------------------------------------------------------ Product Johnson One $87,387,455 12/15/2014 Patient & Johnson Assistance Johnso & Product n Johnson Donation Patien Plaza t New Assist Brunswi ance ck, NJ Founda 08933 tion ------------------------------------------------------------------------ Product Johnson One $74,577,911 9/15/2014 Patient & Johnson Assistance Johnso & Product n Johnson Donation Patien Plaza t New Assist Brunswi ance ck, NJ Founda 08933 tion ------------------------------------------------------------------------ Product MAP 4700 $772,428 1/9/2014 Donation for Intern Glynco Medical ationa Parkway Mission l Brunswi Pack Plus ck, GA Program 31525 ------------------------------------------------------------------------ Product MAP 4700 $26,142 1/9/2014 Donation for Intern Glynco the Medical ationa Parkway Mission l Brunswi Pack Plus ck, GA Program 31525 ------------------------------------------------------------------------ Product MAP 4700 $26,394 12/3/2014 Pharmaceutic Intern Glynco al Product ationa Parkway Donation to l Brunswi support the ck, GA Medical 31525 Mission Pack Plus ------------------------------------------------------------------------ Product Mercy 15862 $8,397 3/19/2014 Product Ships State Donation in Intern Highway support of ationa 110 Humanitaria l North n Relief in Operat Lindale West ions , TX Africa. Center 75771 ------------------------------------------------------------------------ Product New 1 $13,297 8/4/2014 Product Jersey Riversi Donation. Academ de y of Drive Aquati Camden, c NJ Scienc 08103- es 1037 ------------------------------------------------------------------------ Product Project 255 $149,962 3/19/2014 Product Hope Carter Donation in Hall support of Lane Humanitaria Millwoo n Relief in d, VA Kosovo, 22646 Macedonia, and Tajikistan. ------------------------------------------------------------------------ Product Project 255 $768,245 3/10/2014 Product Hope Carter Donation Hall for Lane Humanitaria Millwoo n Relief in d, VA Tajikistan. 22646 ------------------------------------------------------------------------ Product Project 255 $821,994 3/10/2014 Product Hope Carter Donation Hall for Lane Humanitaria Millwoo n Aid in d, VA Tajikistan. 22646 ------------------------------------------------------------------------ Similar payments to the same organization may appear in this report as contributions may be distributed in multiple payments. Janssen Therapeutics, Division of Janssen Products, LP, Monetary and Product Contributions to U.S.-based Charitable Organizations Full Year 2014 (Payments made from January 1, 2014 to December 31, 2014)--Amended March 19, 2019 ------------------------------------------------------------------------ Project Donation Payee Payee Payment Amount Payment Title/ Type Address (USD) Date Description ------------------------------------------------------------------------ Monetary Aboundi South $1,500 3/24/2014 HEALTHY U! . ng Bouleva . . HEALTHY Prospe rd US! rty Dallas, TX 75215 ------------------------------------------------------------------------ Monetary Acercam 827 $7,000 6/16/2014 ContraSIDA iento Wildwoo (Against Hispan d AIDS) o de Avenue Caroli Suite na del 200 Sur Columbi a, SC 29203 ------------------------------------------------------------------------ Monetary Aid for 515 $5,000 11/7/2014 New York AIDS Greenwi Immigrant Intern ch AIDS Link ationa Street Program l New York, NY 10013 ------------------------------------------------------------------------ Monetary AIDS 75 Amory $10,000 11/7/2014 Viral Action Street Hepatitis Commit Boston, Access tee MA Project 02119 (VHAP) ------------------------------------------------------------------------ Monetary AIDS 75 Amory $15,000 3/5/2014 Mental Action Street Health Commit Boston, Program/ tee MA Charitable 02119 Contributio n ------------------------------------------------------------------------ Monetary Aids 575 $20,000 7/9/2014 HIV Health Commun Eighth Literacy ity Avenue Program Resear Suite (HHLP) ch 502 New Initia York, tive NY of 10018 Americ a (ACRIA ) ------------------------------------------------------------------------ Monetary AIDS 6260 $4,500 10/27/2014 Wall Talk Founda Westpar HIV/ tion k Drive Hepatitis C Housto Houston Co- n , TX Infection 77057 ------------------------------------------------------------------------ Monetary AIDS 411 $30,000 7/10/2014 Road to Founda South Health: tion Wells Promoting of Street Successful Chicag Suite Implementat o 300 ion of Chicago Health Care , IL Reform for 60607 People Living with HIV/AIDS in Illinois ------------------------------------------------------------------------ Monetary AIDS 7215 $5,000 12/15/2014 Case Servic Cameron Management e of Road Austin Austin, TX 78752 ------------------------------------------------------------------------ Monetary AIDS 17982 $3,000 8/18/2014 HIV Medical Servic Sky Case es Park Management Center Circle of Irvine, Orange CA County 92614 ------------------------------------------------------------------------ Monetary AIDS 7215 $5,000 4/4/2014 Case Servic Cameron Management es of Road Program Austin Austin, TX 78752 ------------------------------------------------------------------------ Monetary AIDS 1424 K $250,000 11/10/2014 Access to United Street, Care (A2C) NW Initiative Washing ton, DC 20005 ------------------------------------------------------------------------ Monetary Allianc 825 $5,000 7/8/2014 Group Home e for Colorad Care for Housin o Homeless g and Bouleva Persons Healin rd with HIV/ g Suite AIDS at 100 Los Soldano Angeles House and , CA Casa de 90041 Corazon ------------------------------------------------------------------------ Monetary Bay 701 Oak $2,400 1/17/2014 Youth Area Street Engagement Young San Program/ Positi Francis Charitable ves co, CA contributio 94117 n ------------------------------------------------------------------------ Monetary Bay 701 Oak $5,000 11/7/2014 Patient Peer Area Street Navigator Young San Positi Francis ves co, CA 94117 ------------------------------------------------------------------------ Monetary Bienest 5326 E $15,000 11/5/2014 General ar Beverly Organizatio Human Road nal Support Servic Los es Inc Angeles , CA 90022 ------------------------------------------------------------------------ Monetary Caring 19591 S. $20,000 8/18/2014 Patients Ambass Alberta CHOICES--Ch adors Beaverc anging reek, Hepatitis OR through 97004 Outreach, Information , Comprehensi ve Education, and Support ------------------------------------------------------------------------ Monetary Catholi 3009 $5,000 11/7/2014 The Home c Lake Place Charit Brook ies of Bouleva East rd Tennes Knoxvil see le, TN 37909 ------------------------------------------------------------------------ Monetary Chicago 1925 $5,000 2/21/2014 Connect2Care House North (C2C) / and Clybour Charitable Social n Suite Contributio Servic 401 n e Chicago Agency , IL 60614 ------------------------------------------------------------------------ Monetary Chicago 1925 $10,000 12/15/2014 Connect2Care House North and Clybour Social n Suite Servic 401 e Chicago Agency , IL 60614 ------------------------------------------------------------------------ Monetary Christi 2440 $15,000 12/15/2014 CHANGE for e's Third Women Place Avenue Program San Diego, CA 92101 ------------------------------------------------------------------------ Monetary Communi 677 Ala $3,000 3/24/2014 HIV and Hep ty Moana C Health Bouleva Prevention Outrea rd in Drug- ch Suite Using Work 226 Community/ to Honolul Charitable Preven u, HI Contributio t AIDS 96813 n ------------------------------------------------------------------------ Monetary Desert 1695 N. $5,000 1/17/2014 Case Aids Sunrise Management/ Projec Way Charitable t Palm Contributio Springs n , CA 92262 ------------------------------------------------------------------------ Monetary Fund 121 $25,000 11/5/2014 Get SMART For Avenue About The of the Hepatitis C City America of New s 6th York Floor Inc New York, NY 10013 ------------------------------------------------------------------------ Monetary Gay 446 West $15,000 11/7/2014 Community Men's 33rd Education Health Street and Crisis New Treatment York, as NY Prevention 10001 Program ------------------------------------------------------------------------ Monetary HARM South $50,000 4/18/2014 Hepatitis C Reduct Bouleva Innovations ion rd Network/ Coalit Dallas, Charitbale ion TX Contributio 75215 n ------------------------------------------------------------------------ Monetary Health 1211 $75,000 3/17/2014 ``C Change'' Federa Chestnu Program tion t of Street Philad Suite elphia 801 Philade lphia, PA 19107 ------------------------------------------------------------------------ Monetary Hep C 601 $15,000 6/17/2014 HepC Allian Busines Education ce s Loop and 70 West Testing--Th Columbi e Kansas a, MO Project 65203 ------------------------------------------------------------------------ Monetary Hep C 1325 $10,000 3/14/2014 Expanding Connec South Efforts to tion Colorad Locate o Undiagnosed Bouleva HCV rd Patients Suite and Link to 302 Care Denver, CO 80222 ------------------------------------------------------------------------ Monetary Hepatit 35 East $25,000 7/25/2014 The is C 38th Hepatitis C Mentor Street Patient and New Assistance Suppor York, Program t NY Group, 10016 Inc ------------------------------------------------------------------------ Monetary HIV 100 $5,000 3/12/2014 The Aids Edgewoo EmpowerLink Empowe d Program rment Avenue Resour NE ce Suite Center 1020 for Atlanta Young , GA Women, 30303- Inc. 3065 ------------------------------------------------------------------------ Monetary Housing 57 $5,000 11/13/2014 The Works Willoug Undetectabl hby es--HIV Street Viral Brookly Suppression n, NY Initiative 11201 ------------------------------------------------------------------------ Monetary Howard 4025 N. $10,000 7/25/2014 Hepatitis C Brown Sherida Medical Health n Management Center Street and Support Chicago for People , IL who Inject 60613 Drugs ------------------------------------------------------------------------ Monetary Iris 2348 $7,500 2/21/2014 Hepatitis C House Adam Testing, Clayton Education Powell and Jr Connection Bouleva to Care rd New programs/ York, Charitbale NY Contributio 10030 n ------------------------------------------------------------------------ Monetary J&J One $11,200,000 12/19/2014 Global Family Johnson Public of & Health Compan Johnson programs in ies Plaza, South Contri New Africa and bution Brunswi Uganda (HIV s Fund ck, NJ and TB) 08933 ------------------------------------------------------------------------ Monetary Josephs 1730 $5,000 3/13/2014 Care and House Lanier Intensive Place Treatment NW Adherence Washing Support for ton, DC People with 20009 HIV ------------------------------------------------------------------------ Monetary Kansas 3515 $5,000 12/15/2014 Reducing City Broadwa Risks Free y through Health Kansas Health Clinic City, Education MO 64111 ------------------------------------------------------------------------ Monetary Legacy 4054 $5,000 10/27/2014 Mission Counse McKinne Support ling y Legacy Center Avenue Counseling Dallas, Center TX 75204 ------------------------------------------------------------------------ Monetary Maine 35 $5,000 6/23/2014 Harm Genera Medical Reduction l Center Program: Health Parkway HIV and HCV Augusta Prevention , ME 04330 ------------------------------------------------------------------------ Monetary Making 60 Clif $5,000 12/15/2014 Imani Park It Prescod Transitiona Possib Lane l Housing e to Edison, Program End NJ Homele 08817 ssness ------------------------------------------------------------------------ Monetary Minorit 5149 $7,500 2/21/2014 ``The Bridge y AIDS West Program'' Projec Jeffers t on Blvd. Los Angeles , CA 90016 ------------------------------------------------------------------------ Monetary NAESM, 2140 $5,000 6/16/2014 The D.C. Inc. Martin Project Luther King Jr Drive Atlanta , GA 30310 ------------------------------------------------------------------------ Monetary Nashvil 633 $5,000 5/13/2014 Outreach, le Thompso Testing, CARES n Lane Linkage to Nashvil Care, and le, TN Supportive 37204 Services for young AA gay/ bisexual or other MSM ------------------------------------------------------------------------ Monetary Nationa 2140 $7,000 12/15/2014 Project l AIDS Martin Impact Educat Luther ion King and Jr. SW Servic Atlanta es for , GA Minori 30310 ties ------------------------------------------------------------------------ Monetary Nationa 580 $175,000 4/18/2014 NATAP HIV, l AIDS Broadwa HCV/HIV Treatm y Suite Coinfetion ent 1010 and Hep C Advoca New Care and cy York, Treatment Projec NY Education/ t 10012 Information (NATAP and Policy/ ) Advocacy Program ------------------------------------------------------------------------ Monetary Nationa 444 $125,000 3/17/2014 Affordable l North Care Act Allian Capitol (ACA), ce of Street, Viral State NW Hepatitis, and Suite and Ryan Territ 339 White/ADAP orial Washing Public AIDS ton, DC Policy and Direct 20001 Technical ors Assistance Projects/ Charitable Contributio n ------------------------------------------------------------------------ Monetary Nationa 444 $150,000 12/18/2014 2015 l North Affordable Allian Capitol Care Act ce of Street, (ACA), State NW Viral and Suite Hepatitis, Territ 339 and Ryan orial Washing White/ADAP AIDS ton, DC Direct 20001 ors ------------------------------------------------------------------------ Monetary New 44 South $5,000 8/7/2014 Community Jersey Street, Based AIDS Morrist Services Servic own NJ es 07960 ------------------------------------------------------------------------ Monetary North 5 Center $10,000 2/3/2014 Living Well Shore Street with Health Glouces Hepatitis C Projec ter, MA t, 01930 Inc. ------------------------------------------------------------------------ Monetary Nova 2946 $5,000 6/23/2014 En Direccion Salud Sleepyh Positiva ollow Spanish- Road Speaking Suite HIV/AIDS 4A Support Falls Group Church, VA 22044 ------------------------------------------------------------------------ Monetary OPAT 1192 $2,500 3/12/2014 Infectious Outcom Smith Disease es Street Hepatitis C Regist Honolul Virus (HCV) ry u, HI Education, 96817 Screening, Pre/Post Education and Linkage to Care 2014-2015 / Charitable Contributio n ------------------------------------------------------------------------ Monetary Patient 421 $750,000 12/16/2014 Patient Advoca Butler Advocate te Farm Foundation' Founda Road s Co-Pay tion Hampton Relief , VA (CPR) 23666 Program Hepatitis C Silo ------------------------------------------------------------------------ Monetary Patient 421 $5,000,000 1/14/2014 Patient Advoca Butler Advocate te Farm Foundation' Founda Road s Co-Pay tion Hampton Relief , VA (CPR) 23666 Program- Hepatitis C Silo ------------------------------------------------------------------------ Monetary Philade 1233 $10,000 7/9/2014 2014 AIDS lphia Locust Education FIGHT Street Month 3rd Floor Philade lphia, PA 19107 ------------------------------------------------------------------------ Monetary Project 273 $25,000 6/25/2014 Think Tank Inform Ninth to Provide Street Technical San Assistance Francis to Ten co, CA Jurisdictio 94103 ns on the Use of HIV Surveillanc e to Support Linkage and Retention in Care and Treatment ------------------------------------------------------------------------ Monetary Project 273 $40,000 7/1/2014 The Support Inform Ninth Partnership Street San Francis co, CA 94103 ------------------------------------------------------------------------ Monetary Project 273 $40,000 7/4/2014 Mission Inform Ninth Support for Street Project San Inform / Francis Charitable co, CA Contributio 94103 n ------------------------------------------------------------------------ Monetary Project 273 $25,000 12/15/2014 Educational Inform Ninth and Policy Street Activities San to Support Francis Hepatitis C co, CA Care 94103 Linkage ------------------------------------------------------------------------ Monetary Project 2929 NE $2,000 3/12/2014 Many Men, Link 6 Many Voices of Avenue (3MV) and South Wilton Many Women, Florid Manors, Many Voices a, FL (3WV) Inc. 33334 ------------------------------------------------------------------------ Monetary Project 530 W $5,000 11/13/2014 Transitional Transi Street Housing tions Road Warmins ter, PA 18974 ------------------------------------------------------------------------ Monetary Provide 1150 $40,000 7/4/2014 Providence nce Varnum Hepatitis C Health St. NE Program Founda Washing tion ton, DC 20721 ------------------------------------------------------------------------ Monetary Ryan 1775 T $10,000 4/25/2014 HEPATITIS: White Street Education, CARE NW Advocacy Act Washing and Title ton, DC Leadership II 20009 (HEAL) Commun ity AIDS Nation al Networ k (T II CANN) ------------------------------------------------------------------------ Monetary San 1035 $30,000 8/25/2014 The Franci Market Stonewall sco Street Project AIDS San Founda Francis tion co, CA 94103 ------------------------------------------------------------------------ Monetary Southwe 300 $5,000 3/1/2014 HIV Care in st Southwe a Safety Boulev st Net Clinic/ ard Bouleva Charitable Family rd Contributio Health Kansas n Care, City, Inc KS 66103 ------------------------------------------------------------------------ Monetary Special 605 W $5,000 1/28/2014 Asian Servic Olympic Pacific e for Bouleva AIDS Groups rd Interventio , Inc. Suite n Team 600 Los (APAIT) Angeles Charitable , CA Contributio 90015 n ------------------------------------------------------------------------ Monetary The 17 Davis $60,000 3/5/2014 Florida AIDS Bouleva Hepatitis Instit rd Education ute Suite and 403 Advocacy Tampa, Network FL (FHEAN) and 33606 health web portal (www.HepInf oNow.org) / Charitable Contributio n ------------------------------------------------------------------------ Monetary The 17 Davis $50,000 7/9/2014 Protecting AIDS Bouleva and Instit rd enhancing ute Suite the 403 Hepatitis C Tampa, and the HIV/ FL AIDS 33606 national and state programs and policies in the U.S. ------------------------------------------------------------------------ Monetary The 121 $40,000 4/18/2014 The SHE Fund Avenue Initiative for of the the America City s 6th of New Floor York New York, NY 10013 ------------------------------------------------------------------------ Monetary The 330 $15,000 7/22/2014 The Well Well Grace Project's Projec Glen Online t Nellysf Resources ord, VA for Women 22958 and HIV ------------------------------------------------------------------------ Monetary Tides 835 $20,000 11/25/2014 Website: Center Solano HCVAdvocate Street West Sacrame nto, CA 95605 ------------------------------------------------------------------------ Monetary TPA 5537 N $20,000 7/9/2014 Total Care Networ Broadwa Portal k y Incorp Chicago orated , IL -Test 60640 Positi ve Aware Networ k ------------------------------------------------------------------------ Monetary Treatme 261 5th $40,000 6/17/2014 Case Studies nt Avenue Project Action Suite Group 2110 (TAG) New York, NY10016 ------------------------------------------------------------------------ Monetary Univers c/o UC $15,000 3/5/2014 ``Linkage To ity of San Care, After Califo Diego HIV rnia, AIDS Testing''/ San Researc Charitable Diego h Contributio Institu n te 9500 Gilman Drive #0716 La Jolla, CA 92093- 0716 ------------------------------------------------------------------------ Monetary Victory 965 $10,000 2/3/2014 Prevention, Progra Massach Education, ms, usetts and Health Inc. Avenue Connections Boston, Services MA for People 02118 with HIV/ AIDS. ------------------------------------------------------------------------ Monetary VT 187 $5,000 3/13/2014 HIV Care and Commit Saint Support tee Paul Program For Street Across AIDS Burling Vermont Resour ton, VT ces 05401 Educ and Servic es ------------------------------------------------------------------------ Monetary Wright 8101 $5,000 3/3/2014 Case House Cameron Management Wellne Road for HIV/HCV ss Suite Clients Center 105 Austin, TX 78754 ------------------------------------------------------------------------ Janssen has also made financial donations to independent charitable foundations that assist patients who are underinsured and in financial need with treatment-related expenses. In keeping with our donor agreements and applicable regulatory guidance, we will only disclose aggregate data on our charitable giving and do not publicize information on donations to specific foundations and disease states. In 2014, we contributed approximately $5.8 million in donations to independent charitable foundations, enabling them to provide assistance with medication-related copays to patients with infectious diseases. ---------------------------------------------------------------------------------------------------------------- ---------------------------------------------------------------------------------------------------------------- Product Johnson & Johnson One Johnson & $5,615,443 3/15/2013 Patient Assistance Patient Assistance Johnson Plaza, New Product Donation Foundation Brunswick, NJ 08933 ---------------------------------------------------------------------------------------------------------------- Product Johnson & Johnson One Johnson & $9,794,392 6/15/2013 Patient Assistance Patient Assistance Johnson Plaza, New Product Donation Foundation Brunswick, NJ 08933 ---------------------------------------------------------------------------------------------------------------- Product Johnson & Johnson One Johnson & $26,177,458 9/15/2013 Patient Assistance Patient Assistance Johnson Plaza, New Product Donation Foundation Brunswick, NJ 08933 ---------------------------------------------------------------------------------------------------------------- Product Johnson & Johnson One Johnson & $58,375,988 12/15/2013 Patient Assistance Patient Assistance Johnson Plaza, New Product Donation Foundation Brunswick, NJ 08933 ---------------------------------------------------------------------------------------------------------------- Janssen Biotech, Inc. Monetary and Product Contributions to U.S.-based Charitable Organizations Full Year 2015 (Payments made from January 1, 2015 to December 31, 2015)--Amended on February 24, 2017 ------------------------------------------------------------------------ Project Donation Payee Payee Payment Amount Payment Title/ Type Address (USD) Date Description ------------------------------------------------------------------------ Monetary 100 4631 $2,000 7/17/2015 The 100 Black Delmar Black Men Men of St. of Metrop Louis, Metropolita olitan Missour n St. Louis St. i 63108 Community Louis Health Day Featuring Prostate Cancer Run/ Walk ------------------------------------------------------------------------ Monetary 100 4631 $1,800 12/23/2015 The 100 Black Delmar Black Men Men of St. of Metrop Louis, Metropolita olitan Missour n St. Louis St. i 63108 Community Louis Health Day Featuring Prostate Cancer Run/ Walk ------------------------------------------------------------------------ Monetary Achieve 104 $5,625 12/4/2015 Achieve Now: Now Gladsto Bringing ne Students Up Street to Grade Philade Level lphia, Reading PA 19148 ------------------------------------------------------------------------ Monetary America Manasqua $10,000 4/8/2015 Road To n n, NJ Recovery Cancer 08736 Program Societ y, Inc. ------------------------------------------------------------------------ Monetary America Manasqua $1,000 5/27/2015 2015 Run for n n, NJ Dad Cancer 08736 Societ y, Inc. ------------------------------------------------------------------------ Monetary America 1626 $1,000 7/8/2015 American n Locust Cancer Cancer Street Society, Societ Philade Relay For y, lphia, Life of the Inc. PA Wissahickon 19103 Valley, Ambler, PA ------------------------------------------------------------------------ Monetary Arthrit National $225,000 6/5/2015 Sponsorship is Office of 117 Founda 1330 W. Jingle Bell tion Peachtr Run events, ee St., reaching N.W. more than Atlanta 100,000 , GA participant 30309 s and volunteers, across the country ------------------------------------------------------------------------ Monetary Arthrit 1817 $2,000 6/4/2015 The is Central Community Servic Avenue Arthritis es Suite Project of 211 Charlotte, Charlot Mecklenburg te, NC County, 28205 North Carolina ------------------------------------------------------------------------ Monetary Cancer 275 $2,000 7/3/2015 Seventh Care, Seventh Annual Inc. Avenue Healing New Hearts York, Family NY Bereavement 10001 Camp Milford, PA ------------------------------------------------------------------------ Monetary Cancer 3 $5,000 12/2/2015 Oncology Suppor Crossro Support t ads Groups Commun Drive ity Bedmins Centra ter, NJ l New 07921 Jersey ------------------------------------------------------------------------ Monetary Cancer 200 Kirk $1,000 7/10/2015 Paws 4 Life Suppor Road PO Dog Walk, t Box Warminster Commun 3187 PA ity of Warmins Philad ter, PA elphia 18974 (forme rly Gilda' s Club Bucks/ Mont Counti es) ------------------------------------------------------------------------ Monetary Cancer 200 Kirk $2,500 10/23/2015 Celebration Suppor Road PO of Hope: A t Box Free, Full- Commun 3187 Day, ity of Warmins Educational Philad ter, PA and elphia 18974 Inspiration (forme al rly Conference Gilda' for Greater s Club Philadelphi Bucks/ a-Area Mont Cancer Counti Patients, es) Survivors, and Caregivers ------------------------------------------------------------------------ Monetary Center 1900 $2,000 7/9/2015 Project for for Cherry Medically Child Street Needy Advoca Philade Children tes lphia, PA 19103 ------------------------------------------------------------------------ Monetary Childre 6380 $7,500 3/17/2015 Children's ns Flank Cancer Cancer Drive, Recovery Recove Suite Foundation' ry 400 s Bear-Able Founda Harrisb Gift tion urg, PA Program: 17112 administere d to the Children's Hospital of Philadelphi a ------------------------------------------------------------------------ Monetary Childre 6380 $7,500 12/22/2015 Bear-Able ns Flank Gifts Cancer Drive, program Recove Suite ry 400 Founda Harrisb tion urg, PA 17112 ------------------------------------------------------------------------ Monetary Childre The $1,000 12/23/2015 General n's Childre Operating Hospit n's Support for al of Hospita The Center Philad l of for elphia Philade Pediatric Founda lphia Inflammator tion Foundat y Bowel ion Disease Attn: Staci Carney, Associa te Directo r, Corpora te and Foundat ion Relatio ns 100 Penn Square East 8th Floor, Suite 8050 Philade lphia, PA 19107 ------------------------------------------------------------------------ Monetary Childre The $12,000 4/8/2016 Family Care n's Childre Binder Hospit n's Program at al of Hospita The Philad l of Children's elphia Philade Hospital of Founda lphia Philadelphi tion Foundat a ion Philadelphi Attn: a, PA Staci Carney, Associa te Directo r, Corpora te and Foundat ion Relatio ns 100 Penn Square East 8th Floor, Suite 8050 Philade lphia, PA 19107 ------------------------------------------------------------------------ Monetary Childre The $6,000 4/8/2016 6th Annual n's Childre Walk for Hospit n's Hope al of Hospita benefiting Philad l of IBD elphia Philade research at Founda lphia The tion Foundat Children's ion Hospital of Attn: Philadelphi Staci a, Veterans Carney, Park, Associa Hamilton, te NJ Directo r, Corpora te and Foundat ion Relatio ns 100 Penn Square East 8th Floor, Suite 8050 Philade lphia, PA 19107 ------------------------------------------------------------------------ Monetary Communi 300B $20,000 12/8/2015 Free Medical ty Lawrenc and Dental Volunt e Drive Care to eers West Uninsured, in Chester Low-Income Medici , PA Individuals ne 19380 and Families Who Live or Work in Chester County. Community Volunteers in Medicine is located in West Chester, PA ------------------------------------------------------------------------ Monetary Crohns 733 $135,000 6/5/2015 CCFA Take and Third Steps Walk/ Coliti Avenue Run s Suite Founda 510 New tion York, of NY Americ 10017 a ------------------------------------------------------------------------ Monetary Crohn's 733 $18,000 7/7/2015 Camp Oasis-- and Third Program is Coliti Avenue hosted at s Suite 12 campsite Founda 510 New locations tion York, across the of NY country Americ 10017 a, Inc. ------------------------------------------------------------------------ Monetary Delawar 236 $21,500 3/20/2015 Delaware e Randell Valley Valley Hall Science Scienc 3141 Fairs e Chestnu Philadelphi Fairs, t a, PA Inc. Street Philade lphia, PA 19104 ------------------------------------------------------------------------ Monetary Family 2001 $250,000 12/21/2015 Family Reach Reach Route Programmati Founda 46, c Support tion Suite 310 Parsipp any, NJ 07054 ------------------------------------------------------------------------ Monetary Family 2001 $20,000 12/21/2015 Family Reach Reach Route Foundation Founda 46, General tion Suite Support 310 Parsipp any, NJ 07054 ------------------------------------------------------------------------ Monetary Friends 113 West $3,000 12/14/2015 Homelessness Associ Chestnu to ation t Independenc For Street e Care West Initiative and Chester Protec , PA tion 19380 Of Childr en ------------------------------------------------------------------------ Monetary Friends 815 West $825 9/23/2015 Employee of the 7th directed Queen Street donation in City Plainfi Lieu of Academ eld, NJ holiday y 07063 gift Charte r School ------------------------------------------------------------------------ Monetary Georgia Alpharet $1,500 8/12/2015 Georgia Prosta ta, GA Prostate te 30022 Cancer Free Cancer Screening Coalit Event ion, Inc. ------------------------------------------------------------------------ Monetary Georgia Alpharet $1,700 12/23/2015 Georgia Prosta ta, GA Prostate te 30022 Cancer Free Cancer Screening Coalit Event ion, Inc. ------------------------------------------------------------------------ Monetary Girl 330 $3,000 12/14/2015 GSEP STEM Scouts Manor Programming of Road Southe Miquon, astern PA Pennsy 19444 lvania ------------------------------------------------------------------------ Monetary Girl 501 S. $1,250 5/27/2015 16th Annual Scouts College Women of of the Avenue Distinction Chesap Newark, Program and eake DE Celebration Bay 19713 Counci l, Inc. ------------------------------------------------------------------------ Monetary Great PO Box $5,000 12/14/2015 GVNC Valley 82 4251 Environment Nature State al Center Road Education Devault Programs , PA with 19432 Schools- Water Quality, Pond, Stream and Habitat Study ------------------------------------------------------------------------ Monetary Green 1368 $15,000 12/8/2015 Watershed Valley Prizer Education s Road Programs Associ Pottsto ation wn, PA 19465 ------------------------------------------------------------------------ Monetary Habitat P.O. Box $1,000 10/27/2015 Habitat for for 1452 Humanity of Humani 621 Chester ty of Lumber County Cheste Street r Coatesv County ille, , Inc. PA 19320 ------------------------------------------------------------------------ Monetary Habitat 1829 N. $5,000 12/14/2015 Habitat for For 19th Humanity Humani Street Philadelphi ty Philade a Philad lphia, Homeownersh elphia PA ip Program , Inc. 19121 ------------------------------------------------------------------------ Monetary Hatboro- 229 $25,000 12/2/2015 STEM Horsha Meeting Programs m house for Hatboro- Educat Road Horsham ional Horsham Students Founda , PA tion 19044 ------------------------------------------------------------------------ Monetary Hope 129 $300 9/21/2015 Costs for Yerger associated Kids, Road with 2015 Inc. Schwenk Janssen sville, Cares PA Volunteer 19473 Activity ------------------------------------------------------------------------ Monetary Kids 26071 $3,000 9/4/2015 Support Connec Merit Groups for ted Circle, Children of #103 Cancer Laguna Patients Hills, Costa Mesa, CA Ca Brea, Ca 92653- Santa Ana, 7016 Ca Laguna Hills, Ca La Jolla, Ca Temecula, Ca ------------------------------------------------------------------------ Monetary Metropo 2323 $20,000 12/7/2015 Medically litan Ranstea Appropriate Area d Meals for Neighb Street People with orhood Philade Critical Nutrit lphia, Illnesses ion PA Allian 19103 ce (MANNA ) ------------------------------------------------------------------------ Monetary Montgom 340 $10,000 12/15/2015 Bridge to ery DeKalb Employment County Pike Program Commun Blue Enhancement ity Bell, through Colleg PA Strategies e 19422 for Success Founda tion ------------------------------------------------------------------------ Monetary Movembe Culver $5,000 5/22/2015 Movember is r City, a national Founda CA US campaign tion 90232 where we ask men to grow moustaches to raise awareness and funds for men's health ------------------------------------------------------------------------ Monetary Multipl 51 Locus $5,000 7/10/2015 2015 MMRF e Avenue Team for Myelom Suite Cures: New a 201 York City Resear Norwalk 5K Walk/Run ch , CT Founda 06851 tion ------------------------------------------------------------------------ Monetary Multipl 51 Locus $5,000 7/10/2015 2015 MMRF e Avenue Team for Myelom Suite Cures: a 201 Philadelphi Resear Norwalk a 5K Walk/ ch , CT Run Founda 06851 tion ------------------------------------------------------------------------ Monetary Multipl 383 Main $10,000 7/13/2015 MMRF Team e Avenue for Cures Myelom 5th Sponsor--NY a Floor C Marathon, Resear Norwalk (NY, NY) ch , CT and Fenway Founda 06851 Spartan tion Race (Boston, MA ) ------------------------------------------------------------------------ Monetary Nationa 4719 $2,500 4/8/2015 17th Annual l Reed Break the Ovaria Road Silence on n #150 Ovarian Cancer Holicon Cancer Coalit g, PA Philadelphi ion--C 18928 a, PA entral Ohio Chapte r ------------------------------------------------------------------------ Monetary Nationa 6600 SW $75,000 4/14/2015 2015 Team l 02nd NPF Walk-- Psoria Avenue, National sis Ste. (19 U.S. Founda 300 cities) tion Portlan d, OR 97223 ------------------------------------------------------------------------ Monetary Pennypa 7005 $300 9/21/2015 Costs ck Sheaff associated Farm Lane with 2015 and Fort Janssen Educat Washing Cares ion ton, PA Volunteer Center 19034 Activity ------------------------------------------------------------------------ Monetary Project 1515 $1,000 12/2/2015 Mental HOME Fairmou Health and nt Recovery Avenue Services Philade for lphia, Individuals PA Who Have 19130 Experienced Homelessnes s ------------------------------------------------------------------------ Monetary Prostat 7009 S. $30,000 7/13/2015 Prostate e Potomac Cancer Cancer Street Disparities Educat Suite Outreach ion 125 Program--A Counci Centenn national, l ial, CO ten city 80112 event ------------------------------------------------------------------------ Monetary Prostat 7009 S. $20,000 12/23/2015 Prostate e Potomac Cancer Cancer Street Disparities Educat Suite Outreach ion 125 Program--A Counci Centenn national, l ial, CO ten city 80112 event ------------------------------------------------------------------------ Monetary Rebuild P.O. Box $6,000 3/17/2015 House Build ing 42752 Togeth Philade er lphia, Philad PA elphia 19101- 2752 ------------------------------------------------------------------------ Monetary Retired 925 $10,000 3/20/2015 RSVP's My and Harvest Free Tutor Senior Drive, (MFT) and Volunt Suite Family eer 100 Literacy Progra Blue Volunteer m of Bell, Program Montgo PA (FLVP) mery 19422 County ------------------------------------------------------------------------ Monetary Retired 925 $5,000 7/9/2015 RSVP's and Harvest Protege and Senior Drive, America Volunt Suite Reads/ eer 100 Writes Progra Blue Programs m of Bell, Montgo PA mery 19422 County ------------------------------------------------------------------------ Monetary Retired 925 $10,000 12/7/2015 RSVP's and Harvest Family Senior Drive, Literacy Volunt Suite Volunteer eer 100 Program Progra Blue (FLVP) and m of Bell, My Free Montgo PA Tutor (MFT) mery 19422 virtual County STEM tutoring and career awareness program. ------------------------------------------------------------------------ Monetary Riverbe 1950 $6,000 7/3/2015 Outreach to nd Spring Children/ Enviro Mill Access to nmenta Road Nature l Gladwyn (Norristown Educat e, PA , PA) ion 19035 Center ------------------------------------------------------------------------ Monetary Sandy 2010 $2,000 5/15/2015 11th Annual Rollma West Sandy n Chester Sprint 5K/ Ovaria Pike 10K Run/ n Suite Walk Cancer 300 Founda Haverto tion, wn, PA Inc. 19083 ------------------------------------------------------------------------ Monetary Senior 536 $500 8/12/2015 2015 Meals Adult George On Wheels Activi St. Outrunning ties Norrist Senior Center own, PA Hunger 5k/ of 19401 3k. Mont Co Montgo Comm mery College, County Blue Bell, PA. Meals On Wheels of the Senior Adult Activities Center of Montgomery County impacts homebound seniors in Central, North Penn and the Eastern Montgomery Co areas. ------------------------------------------------------------------------ Monetary Senior 536 $300 8/20/2015 Costs Adult George associated Activi St. with 2015 ties Norrist Janssen Center own, PA Cares of 19401 Volunteer Montgo Activity mery County ------------------------------------------------------------------------ Monetary Special 2800 $300 8/20/2015 Costs Equest Street associated rians Road with 2015 P.O. Janssen Box Cares 1001 Volunteer Warring Activity ton, PA 18976 ------------------------------------------------------------------------ Monetary Special 2800 $4,000 9/23/2015 Special Equest Street Equestrians rians Road Equine P.O. Assisted Box Learning 1001 and Warring Therapeutic ton, PA Riding 18976 Program Warrington, PA ------------------------------------------------------------------------ Monetary Starfin 4015 $10,000 3/20/2015 Youth der Main Development Founda Street through tion Philade Soccer and lphia, Education PA Philadelphi 19127 a, PA ------------------------------------------------------------------------ Monetary Stop 2501 $40,700 5/22/2015 Janssen Hunger Clark Biotech and Now Street, Stop Hunger Suite Now Engage 301 Employee Raleigh Volunteers , NC in Dallas, 27607 Texas ------------------------------------------------------------------------ Monetary The 222 $10,000 11/26/2015 Corporate Frankl North Membership in 20th Instit Street ute Philade lphia, PA 19103 ------------------------------------------------------------------------ Monetary The Gwynedd $3,000 7/3/2015 General Giving Valley, Operating Tree PA Support 19437 ------------------------------------------------------------------------ Monetary The 2600 $10,000 4/8/2015 Hubert J.P. Melmar Wayland Schoemaker k Road Classic Charit Berwyn, able PA Founda 19312 tion ------------------------------------------------------------------------ Monetary The 2600 $300 8/21/2015 Costs Melmar Wayland associated k Road with 2015 Charit Berwyn, Janssen able PA Cares Founda 19312 Volunteer tion Activity ------------------------------------------------------------------------ Monetary The 400 $300 8/20/2015 Costs Pennsb Pennsbu associated ury ry with 2015 Societ Memoria Janssen y l Road Cares Morrisv Volunteer ille, Activity PA 19067 ------------------------------------------------------------------------ Monetary Trustee 3025 $5,000 12/23/2015 WXPN s Of Walnut Musicians The Street On Call Univer Philade sity lphia, Of PA Pennsy 19104 lvania ------------------------------------------------------------------------ Monetary United 1709 $260,045 12/23/2015 United Way Way of Benjami Campaign Southe n Match astern Frankli Pennsy n lvania Parkway Philade lphia, PA 19103 ------------------------------------------------------------------------ Monetary Us Too 5003 $1,000 4/8/2015 11th Annual Intern Fairvie SEA Blue ationa w Ave. Prostate l, Downers Cancer 5K Inc. Grove, Run and IL Celebration 60515 Walk in Chicago, IL ------------------------------------------------------------------------ Monetary Zero 515 King $75,000 4/8/2015 ZERO The Street, Prostate Projec Suite Cancer Run/ t To 420 Walk Series End Alexand 40-plus Prosta ria, VA cities te 22314 nationwide Cancer running from March to November 2015 ------------------------------------------------------------------------ Monetary Zero 515 King $8,000 10/23/2015 ZERO The Street, Baltimore Projec Suite Free t To 420 Prostate End Alexand Cancer Prosta ria, VA Screening te 22314 Program Cancer ------------------------------------------------------------------------ Janssen has also made financial donations to independent charitable foundations that assist patients who are underinsured and in financial need with treatment-related expenses. In keeping with our donor agreements and applicable regulatory guidance, we will only disclose aggregate data on our charitable giving and do not publicize information on donations to specific foundations and disease states. In 2015, we contributed $29.5 million in donations to independent charitable foundations, enabling them to provide assistance with medication-related copays to patients with cancer and autoimmune diseases. ---------------------------------------------------------------------------------------------------------------- ---------------------------------------------------------------------------------------------------------------- Product Johnson & Johnson One Johnson & $87,940,000 3/15/2015 Patient Assistance Patient Assistance Johnson Plaza, New Product Donation Foundation Brunswick, NJ 08933 ---------------------------------------------------------------------------------------------------------------- Product Johnson & Johnson One Johnson & $69,856,000 6/15/2015 Patient Assistance Patient Assistance Johnson Plaza, New Product Donation Foundation Brunswick, NJ 08933 ---------------------------------------------------------------------------------------------------------------- Product Johnson & Johnson One Johnson & $60,259,000 9/15/2015 Patient Assistance Patient Assistance Johnson Plaza, New Product Donation Foundation Brunswick, NJ 08933 ---------------------------------------------------------------------------------------------------------------- Product Johnson & Johnson One Johnson & $70,842,000 12/15/2015 Patient Assistance Patient Assistance Johnson Plaza, New Product Donation Foundation Brunswick, NJ 08933 ---------------------------------------------------------------------------------------------------------------- Updated February 24, 2017 Janssen Pharmaceuticals, Inc. Monetary and Product Contributions to U.S.- based Charitable Organizations Full Year 2015 (Payments made from January 1, 2015 to December 31, 2015) ------------------------------------------------------------------------ Project Donation Payee Payee Payment Amount Payment Title/ Type Address (USD) Date Description ------------------------------------------------------------------------ Monetary 180 1 $1,000 11/3/2015 Youth Turnin Bethany Helpline g Road, Lives Buildin Around g 3, , Inc. Suite 42 Hazlet, NJ 07730 ------------------------------------------------------------------------ Monetary Adult 872. E. $600 8/20/2015 Costs Day Main associated Center Street with 2015 of Bridgew Janssen Somers ater, Cares et NJ Volunteer County 08807 Activity ------------------------------------------------------------------------ Monetary Advanci 1005 $2,500 10/23/2015 College ng Whitehe Aspire and Opport ad Road Inquire unitie Extensi Program s, on, Inc. Suite 1 Ewing, NJ 08520 ------------------------------------------------------------------------ Monetary Allies, 1262 $7,500 11/16/2015 Project Grow- Inc. Whiteho Allies Farm rse- Program Hamilto located on n the Grounds Square of Mercer Road County Buildin Community g A, College, Suite West 101 Windsor, NJ Hamilto n, NJ 08690 ------------------------------------------------------------------------ Monetary America 6500 $600 1/22/2015 Employee n Sugarlo directed Cancer af donation in Societ Parkway lieu of y , Suite company 260 holiday Duluth, gift GA 30097 ------------------------------------------------------------------------ Monetary America Buffalo $100 3/12/2015 Memorial n Hope donation Cancer Lodge Societ 197 y Summer Street Buffalo , NY 14222 ------------------------------------------------------------------------ Monetary America 1160 $30,000 10/29/2015 Diabetes n Route Interventio Diabet 22 East n Project es Suite ($30K) and Associ 103 the General ation Bridege Education water, Outreach NJ ($10K) 08807 ------------------------------------------------------------------------ Monetary America 1701 $125,000 12/8/2015 American n North Diabetes Diabet Beaureg Association es ard 's What Can Associ Street I Eat? ation, Alexand Choices for Inc. ria, VA People with 22311 Type 2 Diabetes ------------------------------------------------------------------------ Monetary America 1392 CR $30,000 12/23/2015 Atrial n 2740, Fibrillatio Founda Decatur n Patient tion , TX Education For 76234- and Support Womens 7401 Health ------------------------------------------------------------------------ Monetary America 7272 $10,000 12/8/2015 Garden State n Greenvi Go Red For Heart lle Women Avenue Luncheon Dallas, TX 75231 ------------------------------------------------------------------------ Monetary America 1000 $210,000 12/17/2015 Judges' n Wilson Leadership Psychi Blvd, Initiative- atric Suite Psychiatric Founda 1825 Leadership tion Arlingt for on, VA Criminal 22209 Justice (JLI/PLCJ) ------------------------------------------------------------------------ Monetary America 1000 $35,000 12/17/2015 Partnership n Wilson for Psychi Blvd, Workplace atric Suite Mental Founda 1825 Health tion Arlingt on, VA 22209 ------------------------------------------------------------------------ Monetary America 1000 $100,000 12/17/2015 Typical or n Wilson Troubled? Psychi Blvd, Student atric Suite Mental Founda 1825 Health tion Arlingt Education on, VA Program 22209 ------------------------------------------------------------------------ Monetary America 707 $94,250 12/17/2015 Effort to n Red Alexand support Cross er Road disaster Princet relief on, NJ american 08550 military families, health and safety services, internation al aid, and blood donation services within central New Jersey and across the US ------------------------------------------------------------------------ Monetary AmeriCa 88 $4,600 12/8/2015 General res Hamilto mission Founda n Ave support tion Stamfor d, CT 06902 ------------------------------------------------------------------------ Monetary Anchor 482 $812 4/16/2015 General House, Centre Operating Inc. Street Support Trenton , NJ 08611 ------------------------------------------------------------------------ Monetary Anderso PO Box $300 8/19/2015 Costs n 134 532 associated House Route with 2015 523 Janssen Whiteho Cares use Volunteer Station Activity , NJ 08889 ------------------------------------------------------------------------ Monetary Anderso 532 $19,000 12/3/2015 Integrated n County Care House Road Management 523 P.O. Box 134 Whiteho use Station , NJ 08889 ------------------------------------------------------------------------ Monetary Ann 595 West $9,500 11/12/2015 Ann Silver State Silverman man Street Community Commun Doylest Health ity own, PA Clinic for Health 18901 Bucks Clinic County residents ------------------------------------------------------------------------ Monetary Arc 141 $3,500 11/2/2015 Fundraising Founda South event tion Main support to Of Street benefit Somers Manvill general et e, NJ mission of County 08835 organizatio , Inc. n ------------------------------------------------------------------------ Monetary Associa 819 $9,000 11/16/2015 Partial Care tion Alexand Day for er Road Treatment, Advanc Princet Physical ement on, NJ Health of 08540 Expansion Mental Health ------------------------------------------------------------------------ Monetary Athens 7 N. $1,000 7/1/2015 Mental Mental Congres Health Health s St. Awarenss , Inc. Athens, Event: 2nd OH Annual 45701 Community Illuminatio n ------------------------------------------------------------------------ Monetary Autism 1060 $1,000 11/16/2015 Autism Speaks State Resource Road Fair 2nd Sponsor Floor 2016 Princet Central NJ on, NJ Walk Now 08540 for Autism Speaks ------------------------------------------------------------------------ Monetary Bay 66 Canal $5,000 6/22/2015 Bay Cove Cove St Wellness Human Boston, Center to Servic MA assist es, 02114 diverse low- Inc. income clients who are working towards recovery from severe mental illness ------------------------------------------------------------------------ Monetary Bentley PO Box $300 8/11/2015 Costs Commun 1093 associated ity Belle with 2015 Servic Mead, Janssen es, NJ Cares Inc. 08502 Volunteer Activity ------------------------------------------------------------------------ Monetary Big 2875 $6,500 11/16/2015 The STEM Brothe York School rs Big Road Mentoring Sister Jamison program s of , PA (Centennial Bucks 18966 , Bensalem, County Bristol Township, and Pennsbury school districts in Bucks County, PA) ------------------------------------------------------------------------ Monetary Big 2 West $7,500 10/13/2015 Big Brothers Brothe Washing Big Sisters rs Big ton of Sister Avenue, Hunterdon s of Suite Somerset Hunter 210 PO and Warren don Box 123 Somers Washing et and ton, NJ Warren 07882 Counti es ------------------------------------------------------------------------ Monetary Big 535 East $6,500 9/28/2015 Youth Brothe Frankli Mentoring rs Big n Program Sister Street Support s of Trenton Mercer , NJ County 08610 ------------------------------------------------------------------------ Monetary Boys 212 $22,500 12/8/2015 Career and Centre Launch Girls Street Club Trenton of , NJ Trento 08611 n and Mercer County ------------------------------------------------------------------------ Monetary Bristol 120 $7,500 11/12/2015 ArtRageous Rivers Radclif Theatre ide fe Arts Theate Street Education r Co, Bristol Program Inc. , PA 19007 ------------------------------------------------------------------------ Monetary Broward 305 SE $12,500 7/21/2015 Affordable County 18th Rental Commun Court Housing ity Fort program Develo Lauderd pment ale, FL Corpor 33316 ation, Inc. ------------------------------------------------------------------------ Monetary Bucks 1069 $5,000 11/16/2015 Bucks County County Jackson Veterans Housin ville Housing g Road Assistance Group Ivyland Program , PA 18974 ------------------------------------------------------------------------ Monetary Caminar 2600 S. $2,500 4/9/2015 First Annual El Mental Camino Health Real, Symposium: Suite New 200 San Research in Mateo, Mental CA Health and 94403 its Impact on Treatment ------------------------------------------------------------------------ Monetary Camp P.O. Box $10,000 12/11/2015 Camp Odayin-- Odayin 2068 a camp with Stillwa heart ter, MN 55082 ------------------------------------------------------------------------ Monetary Carrier PO Box $300 8/19/2015 Costs Clinic 147 252 associated Route with 2015 601 Janssen Belle Cares Mead, Volunteer NJ Activity 08502 ------------------------------------------------------------------------ Monetary Catholi 25 Ikea $4,000 10/2/2015 Catholic c Drive Charities, Charit Westham Diocese of ies pton, Trenton On NJ My Own-- 08060 Supportive Housing Program Services ------------------------------------------------------------------------ Monetary Catholi 25 Ikea $15,000 10/6/2015 Partners In c Drive Recovery Charit Westham ies pton, NJ 08060 ------------------------------------------------------------------------ Monetary Catholi 920 $4,000 11/16/2015 CYO's Broad c South St. Center Youth Broad After Organi Street School zation Trenton Program of , NJ Tutoring Mercer 08611 Project County ------------------------------------------------------------------------ Monetary Center 11 $600 8/19/2015 Costs for Minneak associated Educat oning with 2015 ional Road Janssen Advanc Fleming Cares ement ton, NJ Volunteer 08822 activity ------------------------------------------------------------------------ Monetary Center 11 $12,000 11/25/2015 CORE Values for Minneak job Educat oning readiness ional Road program Advanc Fleming ement ton, NJ 08822 ------------------------------------------------------------------------ Monetary Child 204 N. $3,000 9/28/2015 Teen Home West Prenatal and Street and Commun #101 Parenting ity Doylest Continuum own, PA 18901 ------------------------------------------------------------------------ Monetary Childre 635 $5,000 3/30/2015 Fundraising n's South event Home Clinton support to Societ Avenue benefit y of Trenton general New , NJ mission of Jersey 08611 organizatio n ------------------------------------------------------------------------ Monetary Childre 635 $5,000 12/22/2015 Fundraising n's South event Home Clinton support to Societ Avenue benefit y of Trenton general New , NJ mission of Jersey 08611 organizatio n ------------------------------------------------------------------------ Monetary Childre 635 $10,000 12/22/2015 CUNA and n's South Body and Home Clinton Soul Societ Avenue Prenatal y of Trenton Health New , NJ Education Jersey 08611 Program ------------------------------------------------------------------------ Monetary Cit 111 S. $3,000 10/13/2015 Silver level Intern Highlan sponsor of ationa d St. the 2016 l, Box 71 Internation Inc. Memphis al , TN Conference 38111 ------------------------------------------------------------------------ Monetary College 50 Milk $20,000 12/8/2015 Assessing Diabet St 16th the unmet es Floor needs of Networ Boston, young k, MA adults with Inc. 02109 diabetes on college campuses ------------------------------------------------------------------------ Monetary College 2000 $22,500 12/17/2015 Nursing of New Penning Merit Jersey ton Scholarship Road s ($10,000) P.O. and Box Educational 7718 Opportunity Ewing, Fund NJ Promise 08628 Awards ($12,500) ------------------------------------------------------------------------ Monetary Colorad 1031 $2,500 7/28/2015 Peer Support o 33rd Coach Mental Street, Training Wellne Suite ss 237 Networ Denver, k CO 80205 ------------------------------------------------------------------------ Monetary Communi PO Box $5,000 8/18/2015 Rise Summer ty 88 116 Healthy Action North Food Servic Main Initiative e Street for low Center Hightst income , Inc. own, NJ youth. 08520 ------------------------------------------------------------------------ Monetary Communi PO Box $200,000 11/25/2015 Johnson & ty 338 Johnson Founda Morrist Somerset tion own, NJ County of New 07963 Companies Jersey Contributio n Fund at the Community Foundation of NJ ------------------------------------------------------------------------ Monetary Communi 15 $7,000 12/25/2015 Donation to ty Highlan be split Health d evenly Charit Avenue across ies Matawan charitable , NJ organizatio 07747 ns which serve patients in their therapeutic areas ------------------------------------------------------------------------ Monetary Communi P.O. Box $16,000 11/24/2015 Each One, ty 15176 Teach One: Health 407 An Evidence Coalit Crutchf Based ion, ield Diabetes Inc. Street Self- Durham, Management NC Workshop 27704 and Community Leaders Training ------------------------------------------------------------------------ Monetary Communi 959 $12,000 5/15/2015 Pathway to ty Route Recovery Hope, 46 Residential Inc. East, Programs Suite ($10,000) 402 The Annual Parsipp Learning any, NJ Forum on 07054 Mental Health and Wellness Fair ($2,000) ------------------------------------------------------------------------ Monetary Communi 959 $12,000 10/6/2015 Hope for ty Route Veterans Hope, 46 and Valley Inc. East, Brook Suite Village for 402 Veterans Parsipp any, NJ 07054 ------------------------------------------------------------------------ Monetary Communi 310 W. $5,000 9/28/2015 Making the ty State Invisible Justic Street, Visible--Le e 3rd gal Center Floor Services , Inc. Trenton for the , NJ Underserved 08618 ------------------------------------------------------------------------ Monetary Communi 507 E. $4,000 7/1/2015 Compeer ty College Program of Mental Street Johnson Health Iowa County, Center City, Iowa For IA Mid- 52245 Easter n Iowa dba Compee r Progra m, Inc. ------------------------------------------------------------------------ Monetary Compeer 259 $2,500 7/16/2015 Youth and Roches Monroe Family ter, Avenue Mentoring Inc. Rochest Program--Fa er, NY mily 14607 Support ------------------------------------------------------------------------ Monetary Contact 60 S. $5,000 8/18/2015 Fundraising Of Main event Mercer Street support to County Penning benefit New ton, NJ general Jersey 08534 mission of , Inc. organizatio n ------------------------------------------------------------------------ Monetary Contact 60 S. $8,500 12/1/2015 CRISIS Of Main HOTLINE, Mercer Street CRISIS County Penning CHAT, and New ton, NJ TxtToday Jersey 08534 Programs , Inc. ------------------------------------------------------------------------ Monetary CONTACT P.O. Box $3,500 5/14/2015 Crisis We 2376 Interventio Care, Westfie n for Inc. ld, NJ Nonprofessi 07091 onals for People Experiencin g Psychosis ------------------------------------------------------------------------ Monetary Court 1450 $15,000 11/13/2015 CASA of Appoin Parksid Mercer ted e County Specia Avenue, Child l Suite Advocacy Advoca 22 Program for tes Suite Abused and 22 Neglected Ewing, Children NJ 08638 ------------------------------------------------------------------------ Monetary Daytop 362 $2,500 12/10/2015 Daytop of NJ Villag Sunset at Crawford e Of Rd House--work New Skillma readiness Jersey n, NJ initiative , Inc. 08558 ------------------------------------------------------------------------ Monetary Deborah 212 $2,000 11/3/2015 Women's Hospit Trenton Heart al Road Health Founda Browns Symposium tion Mills, NJ 08015 ------------------------------------------------------------------------ Monetary Delawar 14 $300 8/19/2015 Costs e Michael associated River McCorri with 2015 Steamb stin Janssen oat Road Cares Floati Hamilto Volunteer ng n, NJ Activity Classr 08690 oom, Inc. ------------------------------------------------------------------------ Monetary Delawar 14 $4,900 11/16/2015 Environmenta e Michael l education River McCorri for Steamb stin underfunded oat Road and Floati Hamilto underserved ng n, NJ schools and Classr 08690 youth oom, groups Inc. ------------------------------------------------------------------------ Monetary Denver 3501 E $75 2/6/2015 Employee Rescue 46th directed Missio Avenue donation in n Denver, lieu of CO company 80216 holiday gift ------------------------------------------------------------------------ Monetary Depress C/O $1,000 6/4/2015 DBSA NJ ion David Annual and Mizenko Conference Bipola 5 for Support r Village Group Suppor Ct Participant t Lawrenc s Allian eville, ce NJ 08648 ------------------------------------------------------------------------ Monetary Depress C/O $1,000 6/4/2015 DBSA NJ ion David Mutual Aid and Mizenko Support Bipola 5 Group r Village Facilitator Suppor Ct Training t Lawrenc Allian eville, ce NJ 08648 ------------------------------------------------------------------------ Monetary Desert 1695 N. $3,500 7/28/2015 Quality of Aids Sunrise life Projec Way services t Palm for Springs patients , CA with 92262 schizophren ia and schizo- affective disorders ------------------------------------------------------------------------ Monetary Detroit 10 $5,000 7/16/2015 InSHAPE Centra Peterbo Program l City ro (Individual Commun Detroit ized Self ity , MI Health Mental 48201 Action Plan Health for , Inc. Empowerment ) ------------------------------------------------------------------------ Monetary Detroit 645 $750 2/9/2015 Employee Metrop Griswol directed olitan d, donation in Bar Suite lieu of Associ 1356 company ation Detroit holiday Founda , MI gift tion 48226 ------------------------------------------------------------------------ Monetary Diabete 13 $15,000 10/21/2015 Medical s Sunflow Assistance Founda er and Patient tion Avenue, Support Suite Services 1010 Paramus , NJ 07652 ------------------------------------------------------------------------ Monetary Diabete 13 $5,000 12/11/2015 Medical s Sunflow Assistance Founda er and Patient tion Avenue, Support Suite Services 1010 Paramus , NJ 07652 ------------------------------------------------------------------------ Monetary Diabete 319 N. $20,000 12/1/2015 DiabetesSist s Weber ers' Sister Road, Minority s pmb Initiative #163 Bolingb rook, IL 60490 ------------------------------------------------------------------------ Monetary Dress 3131 $9,000 11/16/2015 Roads to for Princet Success: Succes on The Latina s Pike, Literacy Buildin Mobile g 4, Program. Suite 209 Lawrenc eville, NJ 08648 ------------------------------------------------------------------------ Monetary Emory Rollins $10,000 12/23/2015 Emory Latino Univer School Diabetes sity of Education Public Program Health (ELDEP) 1518 Clifton Rd, NE Room 606 Atlanta , GA 30322 ------------------------------------------------------------------------ Monetary Emory Rollins $12,500 12/23/2015 Emory Latino Univer School Diabetes sity of Education Public Program Health (ELDEP) 1518 Clifton Rd, NE Room 606 Atlanta , GA 30322 ------------------------------------------------------------------------ Monetary Enable, 13 $7,500 11/12/2015 Connect with Inc. Roszel Enable Road, Suite B110 Princet on, NJ 08540 ------------------------------------------------------------------------ Monetary Every Fred $9,000 11/16/2015 Every Child Child Vereen, Valued Valued Jr. After A NJ Communi School Nonpro ty Program fit Center Corpor 175 ation Johnson Avenue Lawrenc eville, NJ 08648 ------------------------------------------------------------------------ Monetary Everybo PO Box $4,000 11/16/2015 Coming Up dy 3127 for AIRTM Loves Princet Kenny on, NJ Projec 08543 t, Inc. ------------------------------------------------------------------------ Monetary Family 1931 $9,000 6/4/2015 Outpatient Guidan Notting Mental ce ham Way Health Center Hamilto Treatment Corpor n, NJ for the ation 08619 Chronically Mentally Ill ------------------------------------------------------------------------ Monetary Family 1931 $300 6/26/2015 Costs Guidan Notting associated ce ham Way with 2015 Center Hamilto Janssen Corpor n, NJ Cares ation 08619 Volunteer Activity ------------------------------------------------------------------------ Monetary Family 1931 $300 9/24/2015 Costs Guidan Notting associated ce ham Way with 2015 Center Hamilto Janssen Corpor n, NJ Cares ation 08619 Volunteer Activity September ------------------------------------------------------------------------ Monetary Family 1 AAA $10,000 10/2/2015 Get FIT @ Resour Dr. YMCA ce Suite Networ 203 k Trenton , NJ 08691 ------------------------------------------------------------------------ Monetary Family 4 $9,500 11/16/2015 Nursing Servic Corners services at e tone the Associ Drive emergency ation Langhor homelss of ne, PA shelter Bucks 19047 County ------------------------------------------------------------------------ Monetary Family 790 Park $4,000 4/16/2015 STEPS to Servic Avenue Wellness e Hunting program League ton, NY , Inc. 11743 ------------------------------------------------------------------------ Monetary Federat One $1,000 4/16/2015 Big Nosh ion of Farming Vocational Organi dale Services zation Road s West Babylon , NY 11704 ------------------------------------------------------------------------ Monetary Feed Central $75 1/14/2015 Employee More, Virgini directed Inc. a Food donation in Bank lieu of 1415 company Rhoadmi holiday ller gift Street Richmon d, VA 23220 ------------------------------------------------------------------------ Monetary Feed 333 N. $75 2/25/2015 Employee the Meridia directed Childr n donation in en, Avenue lieu of Inc. Oklahom company a City, holiday OK gift 73107 ------------------------------------------------------------------------ Monetary Forsyth 61 $75 11/19/2015 Employee Humane Miller directed Societ Street donation in y Winston- lieu of Salem, Company NC Holiday 21704 gift ------------------------------------------------------------------------ Monetary Foundat 2381 $2,000 11/16/2015 Fundraising ion of Lawrenc event Morris eville support to Hall/ Road benefit St. Lawrenc general Lawren eville, mission of ce NJ organizatio 08648 n ------------------------------------------------------------------------ Monetary Foundat 2381 $7,500 11/16/2015 Communicatin ion of Lawrenc g for Morris eville Success Hall/ Road St. Lawrenc Lawren eville, ce NJ 08648 ------------------------------------------------------------------------ Monetary Fountai 425 West $1,000 3/30/2015 Silver n 47th sponsor House Street Fountain New House York, Wellness NY Campaign 10036 and One in Four 5K ------------------------------------------------------------------------ Monetary Fountai 425 West $5,000 10/13/2015 Fundraising n 47th event House Street support to New benefit York, general NY mission of 10036 organizatio n ------------------------------------------------------------------------ Monetary Gateway 11901 $7,500 7/16/2015 Support for Homes, Reedy an Inc. Branch Occupationa Road l Therapist Chester field, VA 23238 ------------------------------------------------------------------------ Monetary Georgia 246 $1,500 7/1/2015 Consumer Mental Sycamor scholarship Health e St. s to attend Consum Suite the 24th er 260 Annual Networ Decatur Statewide k , GA Consumer 30030 Conference ------------------------------------------------------------------------ Monetary Girl 1171 $2,000 12/3/2015 GSHNJ Scouts Route Robotics Heart 28 Program of New North Expansion-- Jersey Branch, Make It and , Inc. NJ Take It 08876 ------------------------------------------------------------------------ Monetary Greater 16 W. $100,000 12/22/2015 Greater Trento Lafayet Trenton n te St. Initiative Trenton operating , NJ activities 08608 in support of its strategic plan for 2015 and 2016 ------------------------------------------------------------------------ Monetary Grounds 80 $7,200 12/15/2015 Supporting for Sculpto Wellness Sculpt rs Way Walks for ure Hamilto Low Income n, NJ Seniors 08619 ------------------------------------------------------------------------ Monetary Habitat 601 N $7,500 11/16/2015 Community for Clinton Development Humani Ave Grant for 7- ty--Tr Trenton Plex Build enton , NJ Area 08638- 3446 ------------------------------------------------------------------------ Monetary Habitat 31 Oak $4,000 11/16/2015 Women Build for Ave Homes and Humani Chalfon Strong ty of t, PA Families Greate 18914 r Bucks ------------------------------------------------------------------------ Monetary Habitat 212 Yost $300 8/24/2015 Costs for Bouleva associated Humani rd with 2015 ty of Suite A Janssen Greate Pittsbu Cares r rgh, PA Volunteer Pittsb 15221 Activity urgh ------------------------------------------------------------------------ Monetary Hamilto 1315 $15,000 12/15/2015 Healthy n Area Whiteho Living YMCA rse- Programs: Mercerv Diabetes ille Prevention Road Program Hamilto ($7,500.00) n, NJ , ACT 08619 ($7,500.00) ------------------------------------------------------------------------ Monetary Heart 1325 G $20,000 1/19/2015 Improving Rhythm Street Health Societ NW, Literacy y, Suite and Health Inc. 400 Information Washing in Atrial ton, DC Fibrillatio 20005 n and Stroke Patients ------------------------------------------------------------------------ Monetary Heartla 4750 N. $7,500 7/16/2015 Pathways nd Sherida Home, Health n Road supportive Outrea Chicago housing ch , IL program for 60640 those living with mental health conditions ------------------------------------------------------------------------ Monetary Henders 4740 $5,800 8/5/2015 Mental on North Health Behavi State First Aid: oral Road 7 Helping Health Lauderd Persons in ale Need Lakes, FL 33319 ------------------------------------------------------------------------ Monetary HiTops, 21 $6,000 11/12/2015 HiTops' Inc. Wiggins Adolescent Street Women and Princet Girls' on, NJ Sexual 08540 Health Programming ------------------------------------------------------------------------ Monetary Homecar 240 $100 8/5/2015 Memorial e and North donation Hospic Radnor- e -Cheste Founda r Road, tion Suite 100 Radnor, PA 19087- 5174 ------------------------------------------------------------------------ Monetary HomeFro 1880 $365 7/10/2015 Costs nt Princet associated on Ave. with 2015 Lawrenc Janssen eville, Cares NJ Volunteer 08648 Activity ------------------------------------------------------------------------ Monetary HomeFro 1880 $9,000 10/13/2015 Huchet House nt Princet on Ave. Lawrenc eville, NJ 08648 ------------------------------------------------------------------------ Monetary Hopewel 35 $750 11/16/2015 Hopewell l Princet Elementary Elemen on Science tary Avenue Fair 2016 School Hopewel Parent l, NJ Teache 08525 r Organi zation , Inc. ------------------------------------------------------------------------ Monetary Hopewel P.O. Box $750 12/21/2015 ``aMAZing l 145 Pumpkin Valley Hopewel Carve'' Arts l, NJ Exhibition Counci 08525 l, Inc. ------------------------------------------------------------------------ Monetary Hopewel PO Box $5,400 7/27/2015 Scholarship l 553 for a Valley Penning Hopewell Educat ton, NJ Valley ion 08534 Regional Founda School tion District graduating student ($1,000), district- wide workshops on childhood mental health ($4,400) ------------------------------------------------------------------------ Monetary Hopewel 48 $2,500 2/12/2015 Hopewell l Orchard Valley Valley Avenue Rides Senior Penning Founda ton, NJ tion 08534 ------------------------------------------------------------------------ Monetary Humane 1201 $75 2/3/2015 Employee Societ Macklin directed y of d donation in Missou Avenue lieu of ri St. company Louis, holiday MO gift 63110 ------------------------------------------------------------------------ Monetary Hunterd 1410 $300 8/19/2015 Costs on Route associated County 22 West with 2015 YMCA Annanda Janssen le, NJ Cares 08801 Volunteer Activity ------------------------------------------------------------------------ Monetary Hunterd 1410 $2,500 10/13/2015 Fundraising on Route event County 22 West support to YMCA Annanda benefit le, NJ general 08801 mission of organizatio n ------------------------------------------------------------------------ Monetary Hunterd 8 Main $10,000 4/20/2015 Prescription on Street Drug Abuse Drug Fleming Education Awaren ton, NJ and ess 08822 Evaluation Progra Project. m, Inc. ------------------------------------------------------------------------ Monetary Hunterd 111 Mine $1,000 12/8/2015 Stewardship on Street of the Land Fleming Hunterdon Trust ton, NJ Land 08822 Trust's Dvoor Farm Preserve ------------------------------------------------------------------------ Monetary Institu P.O. Box $3,500 10/2/2015 Nursing te of 7869 Experiences Wonder West hip Program ful Trenton Women , NJ Workin 08628 g For Empowe rment ------------------------------------------------------------------------ Monetary Interfa 3635 $15,000 11/13/2015 Neighbors ith Quakerb Helping Caregi ridge Neighbors vers Rd. Program Trento Suite n, 16 Inc. Hamilto n, NJ 08619 ------------------------------------------------------------------------ Monetary Isles, 10 Wood $7,500 11/16/2015 Healthy Inc. Street Homes Trenton Training to , NJ Reduce 08618 Asthma and Lead ------------------------------------------------------------------------ Monetary Jewish 707 $300 7/14/2015 Costs Family Alexand associated and er with 2015 Childr Road, Janssen en's Suite Cares Servic 102 Volunteer e of Princet Activity Greate on, NJ r 08540 Mercer County ------------------------------------------------------------------------ Monetary Jewish 707 $7,500 12/15/2015 Mercer Family Alexand County and er Caregiver Childr Road, Help Line en's Suite and Servic 102 Caregiver e of Princet Services Greate on, NJ 2016 r 08540 Mercer County ------------------------------------------------------------------------ Monetary Jewish 707 $10,000 12/15/2015 Fundraising Family Alexand event and er support to Childr Road, benefit en's Suite general Servic 102 mission of e of Princet organizatio Greate on, NJ n r 08540 Mercer County ------------------------------------------------------------------------ Monetary Johnson One $6,000,000 6/29/2015 Funding to & Johnson support the Johnso & Johnson & n Johnson Johnson Patien Plaza Patient t New Assistance Assist Brunswi Foundation ance ck, NJ (JJPAF) to Founda 08933 help fund tion their mission to provide pharmaceuti cal product to needy patients on a nondiscrimi natory basis without charge ------------------------------------------------------------------------ Monetary Junior 4365 $5,850 9/25/2015 2016 J&J Achiev Route 1 Pharma Day ement South, Program of New 2nd Jersey flr. Princet on, NJ 08540 ------------------------------------------------------------------------ Monetary Kansas 1919 $450 1/10/2015 Employee Foodba East directed nk Douglas donation in Wareho Wichita lieu of use , KS company 67211 holiday gift ------------------------------------------------------------------------ Monetary Kidsbri 4556 $7,500 9/28/2015 Kidsbridge dge, South Anti- Inc. Broad Bullying St, 2nd Life Skills Floor Program for Trenton At-Risk , NJ Children in 08620 Trenton at the Elementary School Level ------------------------------------------------------------------------ Monetary Lawrenc PO Box $2,500 11/16/2015 WaterBotics: e 6531 17 An Townsh Philips underwater ip Ave. robotics Educat Lawrenc program for ion eville, 6th grade Founda NJ students in tion, 08648 Lawrence Inc. Township Public Schools ------------------------------------------------------------------------ Monetary Leyden 10001 W $5,000 6/23/2015 Peer Support Family Grand Center Servic Ave e and Frankli Mental n Park, Health IL Center 60131 ------------------------------------------------------------------------ Monetary Literac 55 $2,500 11/12/2015 Early y And Primros Childhood-- Life, e Building Inc. Circle Blocks for Princet the Future on, NJ Program 08540 ------------------------------------------------------------------------ Monetary Literac 121 $5,000 9/28/2015 Adult y New Chestnu Literacy Jersey t Program , Inc. Street Suite 203 Roselle , NJ 07203 ------------------------------------------------------------------------ Monetary Literac 120 $4,000 12/1/2015 Let's Talk y Findern About Volunt e Ave-- Health eers Box 7 Literacy of Bridgew Somers ater, et NJ County 08807 ------------------------------------------------------------------------ Monetary Main 8 $2,500 4/16/2015 Serious Street Marcell Mental Counse a Disorders: ling Avenue Improving Center West Access to Orange, Treatment NJ Without 07052 Insurance As an Obstacle ------------------------------------------------------------------------ Monetary Massach 15 $4,000 2/25/2015 Changing usetts Vernon Minds and Clubho Street Improving use Waltham Lives of Coalit , MA People with ion 02453 Mental Illness Project ------------------------------------------------------------------------ Monetary McCarte 91 $12,000 12/15/2015 OnStage r Univers Seniors: A Theatr ity Community e Place Project of Compan Princet McCarter y on, NJ Theatre 08450 ------------------------------------------------------------------------ Monetary Meals 5 Walter $300 8/20/2015 Costs On Foran associated Wheels Blvd with 2015 In Suite Janssen Hunter 2006 Cares don, Fleming Volunteer Inc. ton, NJ Activity 08822 ------------------------------------------------------------------------ Monetary Meals 320 $15,000 10/2/2015 Meals on on Hollowb Wheels Wheels rook Program of Drive Trento Ewing, n NJ Ewing 08638 ------------------------------------------------------------------------ Monetary Mental 2000 N. $90,000 12/17/2015 It's My Health Beaureg Life: Americ ard St. Social Self a 6th Directed Floor Care Alexand ria, VA 22311 ------------------------------------------------------------------------ Monetary Mental 2221 $15,000 7/27/2015 School Health Norfolk Behavioral Americ , Suite Health a of 810 Initiative Greate Houston r , TX Housto 77098 n ------------------------------------------------------------------------ Monetary Mental 2323 W $10,000 8/6/2015 Get Health 5th Connected Americ Ave. program a of Suite Frankl 160 in Columbu County s, OH 43204 ------------------------------------------------------------------------ Monetary Mental 205 $1,500 9/4/2015 2015 Montana Health Haggert Mental Americ y Lane, Health a of Suite Policy Montan 170 Summit a Bozeman , MT 59715 ------------------------------------------------------------------------ Monetary Mental 1210 San $2,500 8/10/2015 Mental Health Antonio Health Americ , Suite Education a of 200 and Texas Austin, Advocacy TX Campaign 78701 ------------------------------------------------------------------------ Monetary Mental 100 W. $1,000 4/16/2015 Bronze Health 10th sponsor Associ St. 2015 E- ation Ste. Racing the in 600 Blues for Delawa Wilming Mental re ton, DE Health 19801 ------------------------------------------------------------------------ Monetary Mental 100 W. $1,500 9/25/2015 Annual Health 10th Community Associ St. Mental ation Ste. Health in 600 Conference- Delawa Wilming -Understand re ton, DE ing Mental 19801 Wellness ------------------------------------------------------------------------ Monetary Mental 617 $2,500 5/22/2015 Support of Health Garden the Mental Associ Street Wellness ation Santa Center in Barbara Santa , CA Barbar 93101 a County ------------------------------------------------------------------------ Monetary Mental 3701 $7,500 6/4/2015 ParentVOICE: Health Latrobe Bringing Associ Drive, Hope to ation Suite Families in of 140 Need Centra Charlot l te, NC Caroli 28211 nas, Inc. ------------------------------------------------------------------------ Monetary Mental 1301 $10,000 7/27/2015 Equitable Health York Access to Associ Road, Effective ation Suite Care of 505 Project--(p Maryla Lutherv rint, web, nd, ille, media, Inc. MD salaries) 21093 ------------------------------------------------------------------------ Monetary Mental 580 $1,000 2/25/2015 Supporting Health White sponsor Associ Plains 2015 MHA on ation Road the Move: of Suite Run/Walk Westch 510 ester Tarryto wn, NY 10591 ------------------------------------------------------------------------ Monetary Mental 1870 $2,000 4/16/2015 Costs Health South associated Associ Boulder with Peer ation Avenue Outreach Oklaho Tulsa, Services ma OK program 74119 ------------------------------------------------------------------------ Monetary Mental 555 N $4,000 6/22/2015 MHA Housing Health Woodlaw Initiative: Associ n, Ste. Ensuring ation 3105 Housing for Reside Wichita Our Most ntial , KS Vulnerable Care, 67208 Populations Inc. ------------------------------------------------------------------------ Monetary Mental 3809 $10,000 7/28/2015 Outreach and Illnes Rosewoo Behavioral s d Drive Healthcare Recove PO Box for ry 4246 Homeless Center Columbi Individuals , Inc. a, SC with Mental 29240 Illness ------------------------------------------------------------------------ Monetary Mercer 3150 $8,000 11/16/2015 Integrating Allian Brunswi housing and ce to ck Pike healthcare End Lawrenc access for Homele eville, veteran and ssness NJ senior 08648- homeless 2420 populations in the Trenton/ Mercer CEASE HOMELESSNES S System ------------------------------------------------------------------------ Monetary Mercer PO Box $19,500 12/15/2015 Supporting County 17202 STEM Commun Trenton Education: ity , NJ Making Colleg 08690 Physics e Available Founda to Students tion at the James Kerney Campus at Trenton ------------------------------------------------------------------------ Monetary Mercer 151 $300 7/10/2015 Costs Street Mercer associated Friend Street with 2015 s Trenton Janssen , NJ Cares 08611 Volunteer Activity ------------------------------------------------------------------------ Monetary Mercer 151 $20,000 10/23/2015 Food Bank- Street Mercer Food Friend Street Distributio s Trenton n Programs , NJ 08611 ------------------------------------------------------------------------ Monetary Middle P.O. Box $15,000 11/24/2015 Outreach Earth 8045 Program and 520 Community North Youth Bridge Centers Street Bridgew ater, NJ 08807 ------------------------------------------------------------------------ Monetary MIDJers 1A $1,500 11/23/2015 Urban Youth ey Quakerb Employment Center ridge Initiative for Plaza Econom Drive, ic Suite 2 Develo Hamilto pment n, NJ 08619 ------------------------------------------------------------------------ Monetary Midland 60 $7,500 10/6/2015 Midland Adult Industr Meals on Servic ial Wheels es, Parkway Employment Inc. PO Box Training 5026 Program North Branch, NJ 08876 ------------------------------------------------------------------------ Monetary Mighty 10th and $100 5/14/2015 Memorial Rivers Poplar Donation Region Cairo, al IL Worshi 62914 p Center ------------------------------------------------------------------------ Monetary Millhil 101 $15,000 10/2/2015 Millhill l Oakland Trenton Child Street PEERS and Trenton Family , NJ 08618 ------------------------------------------------------------------------ Monetary Millhil 101 $5,000 10/2/2015 Trenton Area l Oakland Stakeholder Child Street s and Trenton Family , NJ 08618 ------------------------------------------------------------------------ Monetary Minding 2083 $5,000 6/4/2015 Minding Our Our Lawrenc Business Busine eville Summer ss, Road Program: A Inc. Lawrenc Bridge to eville, the Future NJ for Mercer 08648 County Low- Income Youth ------------------------------------------------------------------------ Monetary Morven 55 $5,000 9/28/2015 Morven Museum Stockto Museum and and n Garden Garden Street Summer Princet Internship on, NJ Program for 08540 Isles of Trenton Youths ------------------------------------------------------------------------ Monetary Mount 73 North $15,000 11/2/2015 Mount Carmel Carmel Clinton Guild Home Guild Avenue Health Trenton Nursing , NJ Program 08609 ------------------------------------------------------------------------ Monetary NAMI--C 1904 $2,000 4/10/2015 Community VA Byrd Mental Centra Avenue, Health l Suite Education Virgin 207 and Social ia's (POB Inclusion Voice 18086) on Richmon Mental d, VA Illnes 23230 s ------------------------------------------------------------------------ Monetary Nami 1401 I- $1,000 7/1/2015 Bronze Alabam 85 sponsor a Parkway 2015 NAMI , Suite Alabama A Walk Montgom ery, AL 36106 ------------------------------------------------------------------------ Monetary NAMI 2400 W. $1,000 2/12/2015 Bronze Delawa 4th St. sponsor re Wilming 2015 ton, DE NAMIWalks 19805 Delaware ------------------------------------------------------------------------ Monetary NAMI 3371 $9,500 8/18/2015 Education Mercer Brunswi and Support NJ ck Programs Pike, Suite 124 Lawrenc eville, NJ 08648 ------------------------------------------------------------------------ Monetary NAMI 85 N. $1,000 8/6/2015 Bronze New State sponsor Hampsh Street 2015 ire Concord NAMIWalks , NH New 03301 Hampshire ------------------------------------------------------------------------ Monetary NAMI of 2100 $7,500 7/28/2015 Living Room- DuPage Manches Peer to County ter Rd, Peer Illino Bldg B, program is Suite 925 Wheaton , IL 60187 ------------------------------------------------------------------------ Monetary NAMI of One $1,500 7/1/2015 Start to Lake Victori Finish County a Sq., sponsor Ste. 2015 260 Strides for Painesv Awareness ille, Walk OH 44077 ------------------------------------------------------------------------ Monetary NAMI of One $2,000 7/1/2015 Supporting Lake Victori Families County a Sq., and Ste. Individuals 260 Impacted by Painesv Schizophren ille, ia: NAMI OH Family-to- 44077 Family Education ------------------------------------------------------------------------ Monetary NAMI of 100 W. $1,000 2/13/2015 Bronze PA Main sponsor Montgo Street 2015 mery Suite Greater County 204 Philadelphi Lansdal a NAMIWalk e, PA 19446 ------------------------------------------------------------------------ Monetary NAMI of 6122 E $1,000 12/15/2015 Bronze Southe 22nd St sponsor rn Tucson, 2016 Arizon AZ Southern a 85711 Arizona NAMIWalks ------------------------------------------------------------------------ Monetary NAMI 1750 S. $1,000 2/27/2015 Bronze St. Brentwo sponsor Louis od 2015 St. Blvd. Louis Suite NAMIWalks 511 St. Louis, MO 63144 ------------------------------------------------------------------------ Monetary NAMI 150 $1,000 5/14/2015 Bronze Summit Cross sponsor County Street, 2015 Akron NAMIWalks Ohio 44311 PO Box 462, Cuyahog a Falls, Ohio 44222 Akron, OH 44311 ------------------------------------------------------------------------ Monetary NAMI 5251 $1,000 3/13/2015 Bronze Ventur Verdugo sponsor a Way, #K 2015 County (PO Box NAMIWalk 1613) Ventura Camaril County lo, CA 93011 ------------------------------------------------------------------------ Monetary NAMI 217 $1,000 6/10/2015 Bronze Waukes Wiscons sponsor ha in Ave 2015 Suite NAMIWalks 300 in Waukesha Waukesh a, WI 53186 ------------------------------------------------------------------------ Monetary Nationa 90 Park $2,500 8/10/2015 27th Annual l Avenue New York Allian 16 Mental ce for Floor Health Resear New Research ch on York, Symposium Schizo NY phreni 10016 a and Depres sion ------------------------------------------------------------------------ Monetary Nationa 90 Park $2,500 9/13/2015 Meet the l Avenue Scientist: Allian 16 A Virtual ce for Floor Q&A Webinar Resear New Series ch on York, Schizo NY phreni 10016 a and Depres sion ------------------------------------------------------------------------ Monetary Nationa 100 $1,000 1/20/2015 Bronze l Clearbr sponsor Allian ook 2015 NAMI ce for Drive Walks the Elmsfor Westchester Mental d, NY ly Ill 10523 ------------------------------------------------------------------------ Monetary Nationa 576 $1,000 1/20/2015 Bronze l Farming sponsor Allian ton 2015 NAMI ce for Avenue Connecticut the Hartfor Walk Mental d, CT ly Ill 06105 ------------------------------------------------------------------------ Monetary Nationa 3250 $1,000 2/13/2015 Bronze l Wilshir sponsor Allian e 2015 ce for Blvd., NAMIWalk the Suite Los Angeles Mental 1501 County ly Ill Los Angeles , CA 90010 ------------------------------------------------------------------------ Monetary Nationa 309 W. $1,000 2/25/2015 Bronze l Millbro sponsor Allian ok 2015 ce for Road, NAMIWalks the Suite Mental 121 ly Ill Raleigh , NC 27609 ------------------------------------------------------------------------ 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$5,000 5/14/2015 Crisis l Wilshir Interventio Allian e n Team ce for Blvd., training the Suite for Custody Mental 1501 Program for ly Ill Los Los Angeles Angeles County , CA Sheriff's 90010 Department ------------------------------------------------------------------------ Monetary Nationa 1225 $10,000 5/14/2015 2015 State l Dublin Conference Allian Road, ce for Suite the 125 Mental Columbu ly Ill s, OH 43215 ------------------------------------------------------------------------ Monetary Nationa 1 Bangor $1,000 6/10/2015 Supporter l Street sponsor Allian Augusta 2015 NAMI ce for , ME Maine the 04330 Annual Mental Awareness ly Ill Walk Walk the Walk to Start the Talk ------------------------------------------------------------------------ Monetary Nationa 3440 $1,000 6/10/2015 Bronze l Viking sponsor Allian Drive 2016 ce for Suite Northern the 104 California Mental Sacrame NAMI Walk ly Ill nto, CA 95827 ------------------------------------------------------------------------ Monetary Nationa PO Box $1,000 7/15/2015 Platinum l 550039 level Allian Birming sponsor ce for ham, AL NAMI the 35255- Birmingham Mental 0039 2015 Walk ly Ill for Mental Health ------------------------------------------------------------------------ Monetary Nationa 808 $1,000 7/15/2015 2015 Annual l Montice Conference, Allian llo ``Shatterin ce for Street g the the Somerse Stigma--Fac Mental t, KY ts vs. ly Ill 42501 Fiction--Ho w Much Do You Know?'' ------------------------------------------------------------------------ Monetary Nationa 1536 W $6,000 7/16/2015 Coming out l Chicago Proud Allian Chicago Program ce for , IL the 60642 Mental ly Ill ------------------------------------------------------------------------ Monetary Nationa PO Box $1,000 7/20/2015 2015 Mental l 4096 Health Allian 2206 N. 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State Mental Box Conference ly Ill 22697 Indiana polis, IN 46222 ------------------------------------------------------------------------ Monetary Nationa 1562 $2,500 9/25/2015 Healing l Route Ourselves, Allian 130 Healing ce for North Others: the Brunswi NAMI NJ Mental ck, NJ 2015 Annual ly Ill 08902 Conference ------------------------------------------------------------------------ Monetary Nationa 3803 N. $75,000 12/17/2015 NAMI l Fairfax Helpline Allian Drive ce for Suite the 100 Mental Arlingt ly Ill on, VA 22203 ------------------------------------------------------------------------ Monetary Nationa 3803 N. $50,000 12/17/2015 NAMI l Fairfax Multicultur Allian Drive al Action ce for Suite Center the 100 Mental Arlingt ly Ill on, VA 22203 ------------------------------------------------------------------------ Monetary Nationa 2012 $1,000 6/10/2015 Bronze l West sponsor Allian 25th NAMIWalks ce for Street, 2015 the #600 Mental Clevela ly nd, OH Ill--G 44113 reater Clevel and ------------------------------------------------------------------------ Monetary Nationa 2012 $2,000 6/23/2015 Mental l West Illness Allian 25th Peer ce for Street, Support and the #600 Education Mental Clevela programs ly nd, OH Ill--G 44113 reater Clevel and ------------------------------------------------------------------------ Monetary Nationa 2753 $1,000 2/13/2015 Bronze l West sponsor Allian Central 2015 NAMI ce for Avenue Walk the Toledo, Mental OH ly Ill 43606 of Greate r Toledo ------------------------------------------------------------------------ Monetary Nationa 505 8th $1,000 2/25/2015 Bronze l Avenue, sponsor Allian Ste 2015 ce for 1103 NAMIWalks the New NYC Mental York, ly Ill NY of New 10018 York City ------------------------------------------------------------------------ Monetary Nationa 1981 $1,000 11/17/2015 Bronze l Marcus sponsor Allian Ave, 2016 Long ce for C117 Island/ the Lake Queens/ Mental Success NAMIWalks ly Ill , NY Queens/ 11042 Nassau ------------------------------------------------------------------------ Monetary Nationa 5963 $1,000 7/27/2015 Bronze l Boymel sponsor Allian Dr. 2015 ce on Fairfie National Mental ld, OH Alliance on Illnes 45014 Mental s Illness of Butler County NAMIWAlk ------------------------------------------------------------------------ Monetary Nationa 324A $1,000 1/9/2015 Gold sponsor l Springf of the 2015 Allian ield NAMI-WM ce on Street Annual Mental Agawam, Walkathon: Illnes MA A Journey s 01001 of Hope and Wester Recovery n Mass., Inc. ------------------------------------------------------------------------ Monetary Nationa PO Box $6,000 4/16/2015 28 Annual l Art 350891 National Exhibi Miami, Art tions FL Exhibition of the 33135 by the Mental Mentally ly Ill Ill, Inc. ------------------------------------------------------------------------ Monetary Nationa 110 N $30,000 12/1/2015 MY BLOOD l Washing CLOT--An Blood ton St. Online Clot Suite Resource Allian 328 for ce Rockvil Patients le, MD and 20850 Caregivers Managing Life with VTE ------------------------------------------------------------------------ Monetary Nationa 1400 K $75,000 12/17/2015 2016 Policy l Street Action Counci NW, Center l for Suite Behavi 400 oral Washing Health ton, DC 20005 ------------------------------------------------------------------------ Monetary Nationa 1400 K $75,000 12/17/2015 Early Onset l Street Psychosis Counci NW, Project l for Suite Behavi 400 oral Washing Health ton, DC 20005 ------------------------------------------------------------------------ Monetary Nationa 1400 K $75,000 12/17/2015 Health l Street Justice Counci NW, Learning l for Suite Initiative Behavi 400 oral Washing Health ton, DC 20005 ------------------------------------------------------------------------ Monetary Nationa 949 W. $7,500 11/16/2015 Academic l State Creative Junior Street Engagement Tennis Trenton (ACE) and and , NJ STEM Pilot Learni 08618 Program ng of Trento n ------------------------------------------------------------------------ Monetary Nationa 9707 E $100 11/3/2015 Memorial l Easter Donation Stroke Lane, Associ Suite B ation Centenn ial, CO 80112 ------------------------------------------------------------------------ Monetary Nationa 9707 E $15,000 12/3/2015 Navigator l Easter training, Stroke Lane, program Associ Suite B development ation Centenn , services ial, CO delivered, 80112 participant materials and resources, and outcomes measurement . ------------------------------------------------------------------------ Monetary Nationa 9707 E $35,000 12/4/2015 Develop a l Easter multi- Stroke Lane, channel Associ Suite B marketing ation Centenn plan ial, CO 80112 ------------------------------------------------------------------------ Monetary New P.O. 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AmeriCa 88 $897,021 12/8/2015 Product res Hamilto donation Founda n Ave for tion Stamfor humanitaria d, CT n 06902 assistance in Armenia, Nicaragua, Peru, US ------------------------------------------------------------------------ Product AmeriCa 88 $48,945 12/21/2015 Product res Hamilto donation Founda n Ave for tion Stamfor humanitaria d, CT n 06902 assistance in USA ------------------------------------------------------------------------ Product AmeriCa 88 $2,005,526 12/21/2015 Product res Hamilto donation Founda n Ave for tion Stamfor humanitaria d, CT n 06902 assistance in USA ------------------------------------------------------------------------ Product Catholi 100 Wall $812,025 3/10/2015 Product c Street, donation Medica 9th for l Floor humanitaria Missio New n n York, assistance Board NY in Haiti, 10005 Honduras, Jamaica, Nicaragua ------------------------------------------------------------------------ Product Catholi 100 Wall $105,683 3/10/2015 Product c Street, donation Medica 9th for l Floor humanitaria Missio New n n York, assistance Board NY in Haiti, 10005 Jamaica ------------------------------------------------------------------------ Product Catholi 33-01 $275,375 6/4/2015 Product c Elevent donation Medica h for l Street humanitaria Missio Long n n Island assistance Board City, in Jamaica, NY Armenia, Guatemala ------------------------------------------------------------------------ Product Catholi 33-01 $313,574 6/29/2015 Product c Elevent donation Medica h for l Street humanitaria Missio Long n n Island assistance Board City, in El NY Salvador ------------------------------------------------------------------------ Product Catholi 100 Wall $1,612,989 10/9/2015 Product c Street, donation Medica 9th for l Floor humanitaria Missio New n n York, assistance Board NY in 10005 Guatemala, Honduras, Haiti ------------------------------------------------------------------------ Product Catholi 100 Wall $563,598 10/9/2015 Product c Street, donation Medica 9th for l Floor humanitaria Missio New n n York, assistance Board NY in 10005 Guatemala, Honduras, Haiti ------------------------------------------------------------------------ Product Catholi 33-01 $8,754 11/4/2015 Product c Elevent donation Medica h for l Street humanitaria Missio Long n n Island assistance Board City, in NY Dominican Republic, El Salvador, Guyana, Nicaragua ------------------------------------------------------------------------ Product Catholi 33-01 $343,347 12/18/2015 Product c Elevent donation Medica h for l Street humanitaria Missio Long n n Island assistance Board City, in El NY Salvador, Dominican Republic, Sierra Leone, Uganda, Guatemala, Guyana, Philippines ------------------------------------------------------------------------ Product Direct 27 S. La $2,014,130 3/10/2015 Pharmaceutic Relief Patera al Product Lane Donation Goleta, for CA Humanitaria 93117 n Aid in Dominican Republic, El Salvador, Guatemala, Haiti, US ------------------------------------------------------------------------ Product Direct 27 S. La $274,761 3/10/2015 Product Relief Patera donation Lane for Goleta, humanitaria CA n 93117 assistance in Dominican Republic, Ghana, Guatemala, Nicaragua, US ------------------------------------------------------------------------ Product Direct 27 S. La $17,185 4/2/2015 Pharmaceutic Relief Patera al Product Lane Donation Goleta, for CA Humanitaria 93117 n Aid in Paraguay ------------------------------------------------------------------------ Product Direct 27 S. La $13,131 5/4/2015 Product Relief Patera donation Lane for Goleta, humanitaria CA n 93117 assistance in Nepal (2015 earthquake relief) ------------------------------------------------------------------------ Product Direct 27 S. La $10,680 5/5/2015 Product Relief Patera donation Lane for Goleta, humanitaria CA n 93117 assistance in Congo, Malawi, Mali, Somalia, Tanzania, Zambia (obstetric fistula program) ------------------------------------------------------------------------ Product Direct 27 S. La $187,713 5/20/2015 Product Relief Patera donation Lane for Goleta, humanitaria CA n relief in 93117 El Salvador, Guatemala, Dominican Republic, United States ------------------------------------------------------------------------ Product Direct 27 S. La $852,327 6/4/2015 Product Relief Patera donation Lane for Goleta, humanitaria CA n 93117 assistance in Paraguay, El Salvador, Nicaragua ------------------------------------------------------------------------ Product Direct 27 S. La $9,636,065 6/29/2015 Product Relief Patera donation Lane for Goleta, humanitaria CA n 93117 assistance in Haiti, India, Jamaica, Paraguay, Armenia, Dominican Republic, Ghana, Guatemala, Hondorus, US ------------------------------------------------------------------------ Product Direct 27 S. La $20,976 8/4/2015 Product Relief Patera donation Lane for Goleta, humanitaria CA n 93117 assistance in Paraguay ------------------------------------------------------------------------ Product Direct 27 S. La $13,878 8/5/2015 Product Relief Patera donation Lane for Goleta, humanitaria CA n 93117 assistance in Africa ------------------------------------------------------------------------ Product Direct 27 S. La $198,318 9/11/2015 Product Relief Patera donation Lane for Goleta, humanitaria CA n 93117 assistance: disaster relief preparednes s ------------------------------------------------------------------------ Product Direct 27 S. La $5,543,118 10/12/2015 Product Relief Patera donation Lane for Goleta, humanitaria CA n 93117 assistance in Nicaragua, Sierra Leone, Ghana, US and for disaster preparednes s modules ------------------------------------------------------------------------ Product Direct 27 S. La $918,456 10/12/2015 Product Relief Patera donation Lane for Goleta, humanitaria CA n 93117 assistance in Ghana, Sierra Leone, Nicaragua, US ------------------------------------------------------------------------ Product Direct 27 S. La $81,702 11/4/2015 Product Relief Patera donation Lane for Goleta, humanitaria CA n 93117 assistance in Cambodia, Guatemala, Haiti, Honduras, India, Paraguay ------------------------------------------------------------------------ Product Direct 27 S. La $27,755 11/25/2015 Product Relief Patera donation Lane for Goleta, humanitaria CA n 93117 assistance in Africa (obstetric fistula program) ------------------------------------------------------------------------ Product Direct 27 S. La $186,387 12/7/2015 Product Relief Patera donation Lane for Goleta, humanitaria CA n 93117 assistance in Ecuador, Ghana, Mexico, Jamaica ------------------------------------------------------------------------ Product Heart 13250 W $4,874,474 10/6/2015 Product To 98th donation Heart Street for Intern Lenexa, humanitaria ationa KS n l 66215 assistance in Dominican Republic, Papua New Guinea ------------------------------------------------------------------------ Product Heart 13250 W $1,148,070 10/6/2015 Product To 98th donation Heart Street for Intern Lenexa, humanitaria ationa KS n l 66215 assistance in Dominican Republic ------------------------------------------------------------------------ Product Johnson One $299,754,483 12/31/2015 Patient & Johnson Assistance Johnso & Product n Johnson Donation Patien Plaza t New Assist Brunswi ance ck, NJ Founda 08933 tion ------------------------------------------------------------------------ Product MAP 4700 $2,230,112 2/20/2015 Pharmaceutic Intern Glynco al Product ationa Parkway Donation to l Brunswi support the ck, GA Medical 31525 Mission Pack+ Program ------------------------------------------------------------------------ Product MAP 4700 $1,312,483 7/20/2015 Global Intern Glynco Public ationa Parkway Health l Brunswi programs in ck, GA Sub Saharan 31525 Africa (HIV) ------------------------------------------------------------------------ Product MAP 4700 $46,453 9/11/2015 Product Intern Glynco donations ationa Parkway for l Brunswi humanitaria ck, GA n 31525 assistance: Medical Mission Pack Plus replenishme nt ------------------------------------------------------------------------ Product MAP 4700 $35,015 11/25/2015 Product Intern Glynco donation ationa Parkway for l Brunswi humanitaria ck, GA n 31525 assistance and medical mission pack + program ------------------------------------------------------------------------ Product MAP 4700 $951,077 12/15/2015 Product Intern Glynco donation ationa Parkway for l Brunswi humanitaria ck, GA n 31525 assistance (medical mission pack + program) ------------------------------------------------------------------------ Product US 1300 PA $29,310,000 12/17/2015 Global Agency Avenue. Public for , NW, Health Intern SA-44 programs--B ationa Rm 475- edaquiline l J Donation Develo Washing Program pment ton, DC 20523 ------------------------------------------------------------------------ Updated March 24, 2016 Janssen Therapeutics, Division of Janssen Products, LP, Monetary and Product Contributions to U.S.-based Charitable Organizations Full Year 2015 (Payments made from January 1, 2015 to December 31, 2015) ------------------------------------------------------------------------ Project Donation Payee Payee Payment Amount Payment Title/ Type Address (USD) Date Description ------------------------------------------------------------------------ Monetary Aboundi 2311 $5,000 5/8/2015 Project ng Martin CONNECT Prospe Luther rty, King Inc. Blvd Dallas, TX 75215 ------------------------------------------------------------------------ Monetary Aboundi 2311 $15,000 11/13/2015 Confidential ng Martin and Mature Prospe Luther Explanation rty, King s (C-ME): Inc. Blvd HCV Dallas, Awareness TX for At-Risk 75215 Adults in South Dallas ------------------------------------------------------------------------ Monetary Aboundi 2311 $30,000 12/22/2015 Project TEST ng Martin Prospe Luther rty, King Inc. Blvd Dallas, TX 75215 ------------------------------------------------------------------------ Monetary Acercam 827 $7,000 5/8/2015 ContraSIDA iento Wildwoo (Againsts Hispan d Ave, AIDS) o de Suite Caroli 200 na del Columbi Sur a, SC 29203 ------------------------------------------------------------------------ Monetary ADAP PO Box $5,000 3/16/2015 ADAP Advoca 15275 Directory cy Physica l:312 11th Avenue, #21g, New York, NY 10001 Washing ton, DC 20003 ------------------------------------------------------------------------ Monetary Aid For 515 $10,000 7/13/2015 Case AIDS Greenwi Management Intern ch St Program ationa New l, York, Inc. NY 10013 ------------------------------------------------------------------------ Monetary AID 811 $18,259 12/22/2015 Project Upstat Pendlet Healthy e on Pink Parts Street Bldg. #10 Greenvi lle, SC 29601 ------------------------------------------------------------------------ Monetary AIDS 75 Amory $15,000 11/13/2015 Viral Action Street Hepatitis Commit Boston, Access to tee of MA Care Massac 02119 Project: husett Access to s treatment ------------------------------------------------------------------------ Monetary AIDS 995 $5,000 7/27/2015 Bridges Care Northwe Project Servic st e, Bouleva Inc. rd Winston Salem, NC 27101 ------------------------------------------------------------------------ Monetary AIDS 575 8th $20,000 7/13/2015 HIV Health Commun Ave, Literacy ity Suite Education Resear 502 New and ch York, Training Initia NY for Service tive 10018 Providers of Working Americ with a Vulnerable ACRIA Populations ------------------------------------------------------------------------ Monetary AIDS 6260 $3,000 5/27/2015 Supportive Founda Westpar Services tion k Drive Housto Suite n, 100 Inc. Houston , TX 77057 ------------------------------------------------------------------------ Monetary AIDS 200 W. $40,000 5/20/2015 Road to Founda Jackson Health: tion Blvd., Promoting of Suite Successful Chicag 2100 Implementat o Chicago ion of , IL Health Care 60606 Reform for People Living with HIV/AIDS in Illinois ------------------------------------------------------------------------ Monetary AIDS 400 N $5,000 3/12/2015 Case Outrea Beach Management ch Street, Program for Center Suite People 100 Ft. Living with Worth, HIV TX 76111 ------------------------------------------------------------------------ Monetary AIDS 1320 $28,020 12/22/2015 Transcend Projec Webster t of Street the oakland East , CA Bay 96612 ------------------------------------------------------------------------ Monetary AIDS 1424 K $150,000 11/17/2015 Disseminatio United Street, n of Access NW, to Care and Ste. Retention 200 in Care Washing Best ton, DC Practices 20005 ------------------------------------------------------------------------ Monetary AIDS Box 3068 $5,000 3/13/2015 Latino Walk San Services San Diego, Diego CA 92163 ------------------------------------------------------------------------ Monetary Alexian 825 W. $5,000 7/15/2015 Transitional Brothe Welling Living rs ton Program for Bonave Chicago Homeless nture , IL Adults with House 60657 HIV/AIDS Case Management Services ------------------------------------------------------------------------ Monetary Alivene 3808 $5,000 5/27/2015 Health and ss Nicolle Wellness Projec t Ave Program: t, Minneap Aging with Inc. olis, HIV/AIDS MN 55409 ------------------------------------------------------------------------ Monetary Allianc 825 $3,000 5/27/2015 Nurse Case e For Colorad Management Housin o for g And Blvd., Residential Healin Suite Care g 100 Los Facility Angeles Serving , CA Homeless 90041 Persons with HIV/ AIDS ------------------------------------------------------------------------ Monetary Atlanta P.O. Box $32,000 4/16/2015 Comprehensiv Harm 92670 e HIV and Reduct Atlanta HCV ion , GA treatment Coalit 30314 for IDUs ion ------------------------------------------------------------------------ Monetary BASIC 432 $5,000 5/15/2015 Fully NWFL, Magnoli Committed INC. a Avenue Panama City, FL 32401 ------------------------------------------------------------------------ Monetary BASIC 432 $29,250 12/22/2015 FULLY NWFL, Magnoli COMMITTED: INC. a Improving Avenue Linkage to Panama Care and City, Retention FL among Young 32401 MSM of Color Living with HIV ------------------------------------------------------------------------ Monetary Bay 701 Oak $5,000 12/21/2015 Patient Peer Area Street Navigation Young San Positi Francis ves co, CA 94117 ------------------------------------------------------------------------ Monetary Brockto 500 $5,000 3/24/2015 HIV/AIDS n Area Belmont Case Multi- Street Management Servic Ste 300 Initiative es, Brockto and Inc. n, MA Hepatitis C 02301 Support Group. ------------------------------------------------------------------------ Monetary Bronx 540 East $40,000 3/10/2015 Improving AIDS Fordham Care and Servic Rd Treatment es, Bronx, for People Inc. NY who Inject 10458 Drugs (PWID) who are Living with HIV and/or Hepatitis C ------------------------------------------------------------------------ Monetary Caring PO Box $40,000 5/20/2015 Hepatitis C Ambass 1748 Program adors Oregon Support Progra City, m, OR Inc. 97045 ------------------------------------------------------------------------ Monetary Center 900 $25,000 3/10/2015 Hepatitis for Avila and HIV Health Street, Navigation Justic Suite Project--RF e 301, A Los Angeles , CA 90012 ------------------------------------------------------------------------ Monetary Central 1785 $5,000 10/12/2015 Increasing Louisi Jackson Timely ana Street Access to Aids Alexand HIV Care, Suppor ria, LA Testing and t 71301 Prevention Servic Services es, Inc. (CLASS ) ------------------------------------------------------------------------ Monetary Coaliti 127 W $50,000 12/21/2015 Hepatitis C on On 127th Education Positi street and ve Suite Services Health 208 New Project Empowe York, rment, NY Inc. 10027 ------------------------------------------------------------------------ Monetary Coastal 400 Mann $40,000 3/24/2015 Hepatitis Bend Street, Education AIDS Suite Program Founda 800 (HEP) tion Corpus Christi , TX 78401 ------------------------------------------------------------------------ Monetary Communi 677 Ala $7,500 10/3/2015 Integrating ty Moana Hepatitis Health #226 Care Outrea Honolul Coordinatio ch u, HI n into Work 96813 Hawaii AIDS To Service Preven Organizatio t Aids ns ------------------------------------------------------------------------ Monetary Desert 1695 N. $5,000 3/16/2015 Get Tested Aids Sunrise Coachella Projec Way Valley t Palm Springs , CA 92262 ------------------------------------------------------------------------ Monetary Exponen 2 $5,000 11/16/2015 HEPAware ts, Washing Project Inc. ton Street, Fourth Floor New York, NY 10004 ------------------------------------------------------------------------ Monetary Gay 446 W $15,000 10/3/2015 HIV Men's 33rd St Community Health New Education Crisis York, and NY Treatment 10001 Adherence Support ------------------------------------------------------------------------ Monetary Gay 446 W $30,000 12/22/2015 Peer Men's 33rd St Navigation Health New Services Crisis York, for HIV- NY positive 10001 Transgender and Gender Non- Conforming Individuals ------------------------------------------------------------------------ Monetary Harm 22 West $30,000 6/5/2015 Hepatitis C Reduct 27th and ion Street Injection Coalit 5th Drug Use ion Floor Initiative New York, NY 10001 ------------------------------------------------------------------------ Monetary Hips HIPS $30,000 12/22/2015 Treatment Center Plus: Peer for Based Health Community and Health Achieve Worker ment Support to 906 H Improve St., NE Health Washing Outcomes ton, DC for Highly 20002 Marginalize d Transgender Women ------------------------------------------------------------------------ Monetary Housing 301 West $7,500 12/8/2015 Hepatitis C Works, 37th Peer Inc. Street, Navigator #3 New Program York, NY 10018 ------------------------------------------------------------------------ Monetary Jackson P.O. Box $5,000 8/27/2015 JASMYN ville 380103 Safety Net Area 923 Program Sexual Peninsu Expansion Minori lar ty Place Youth Jackson Networ ville, k, FL Inc. 32205 (JASMY N) ------------------------------------------------------------------------ Monetary Legacy 4054 $5,000 12/21/2015 Counseling Counse McKinne services to ling y individuals Center Avenue, living with Suite HIV/AIDS 102 Dallas, TX 75204 ------------------------------------------------------------------------ Monetary Long 2740 $30,000 12/22/2015 Pride for Island Martin Youth POZ Crisis Ave Night Center Bellmor , Inc. e, NY 11710 ------------------------------------------------------------------------ Monetary Macedon 1835 $5,000 3/24/2015 Peer ia Centre Navigator Family Avenue, for And Suite Prevention/ Commun 285 Case ity Pittsbu Management Enrich rgh, PA Services ment 15219 Center ------------------------------------------------------------------------ Monetary Macedon 1835 $5,000 10/23/2015 Peer ia Centre Navigator Family Avenue, for And Suite Prevention/ Commun 285 Case ity Pittsbu Management Enrich rgh, PA Services ment 15219 Implementat Center ion ------------------------------------------------------------------------ Monetary MCCNY 446 West $30,000 12/23/2015 Trans in Charit 36th Action ies Street New York, NY 10018 ------------------------------------------------------------------------ Monetary Mendoci 148 $39,870 3/30/2015 Linkage and no Clara Support County Ave. Services AIDS Ukiah, for PWID's Volunt CA eer 95482 Networ k adba Mendoc ino County AIDS/ Viral Hepati tis Networ k ------------------------------------------------------------------------ Monetary Metropo 3251 3rd $30,000 12/23/2015 TransHealth litan Avenue Care Charit North Coordinatio ies, Suite#1 n Inc. 25 St Petersb urg, FL 33713 ------------------------------------------------------------------------ Monetary Minorit 5149 W. $7,500 4/30/2015 ``G.L.A.M.O. y AIDS Jeffers R.'' Projec on Blvd Getting t Los Linked And Angeles Managing , CA Our 90016 Regimen. It is The Missing Link. ------------------------------------------------------------------------ Monetary Missour 601 $18,000 3/24/2015 General i Busines Charitable Hepati s Loop Contributio tis C 70 n Allian West, ce Suite 134K, Columbi a, MO 65203- 2585 ------------------------------------------------------------------------ Monetary Montgom 820 W. $18,000 3/13/2015 Alabama ery Wouth eHealth AIDS Blvd., Access to Outrea Montgom Rural care ch ery, AL for HIV/ 36105 AIDS and Hepatitis C ------------------------------------------------------------------------ Monetary Nashvil 633 $18,000 12/22/2015 Brothers le Thompso United CARES, n Lane Network of Inc. Nashvil Tennessee: le, TN Mobilizatio 37204 n of Young African American MSM in Rural Middle and East Tennessee ------------------------------------------------------------------------ Monetary Nationa 2140 $5,000 7/15/2015 Brothers l AIDS Martin Like Us Educat Luther (B.L.U.) ion King Project and Jr. Servic Drive es for Atlanta Minori , GA ties 30310 ------------------------------------------------------------------------ Monetary Nationa 2140 $30,000 12/22/2015 Be Connected l AIDS Martin Mentoring Educat Luther Program ion King and Jr. Servic Drive es for Atlanta Minori , GA ties 30310 ------------------------------------------------------------------------ Monetary Nationa 580 $200,000 2/25/2015 Hepatitis C l AIDS Broadwa Project, Treatm y Suite HIV Too ent 1010 Advoca New cy York, Projec NY t 10012 ------------------------------------------------------------------------ Monetary Nationa National $150,000 11/17/2015 Affordable l Latino Care Act Allian AIDS (ACA), ce of Action Viral State Network Hepatitis, and and and Ryan Territ Nationa White/ADAP orial l Public AIDS Allianc Policy and Direct e of Technical ors State Assistance and Programs Territo rial AIDS Directo rs 444 N Capitol St Suite 339 Washing ton, DC 20001 ------------------------------------------------------------------------ Monetary Nationa Post $7,500 7/27/2015 Black LGBT l Office Health and Black Box Wellness Justic 71395 Initiative e Washing Coalit ton, DC ion, 20024 Inc. ------------------------------------------------------------------------ Monetary Nationa 1825 $35,000 3/10/2015 Strong l Connect Communities Minori icut : ty Avenue, Strengtheni AIDS NW ng Counci Washing connections l ton, DC between 20009- communities 5721 of color and the healthcare providers that serve them. ------------------------------------------------------------------------ Monetary New 44 South $5,000 8/27/2015 Support of Jersey Street case AIDS Morrist management Servic own, NJ es 07960 ------------------------------------------------------------------------ Monetary Next 99 $5,000 7/27/2015 Next Step Step Bishop Transitiona Fund, Allen l Support Inc. Drive for HIV+ Cambrid Teens and ge, MA Young 02139 Adults ------------------------------------------------------------------------ Monetary Our 2727 SE $5,000 3/13/2015 NHCP: House Alder Independent Of St. Living Portla Portlan Support for nd d, OR Individuals Incorp 97214 with HIV/ orated AIDS ------------------------------------------------------------------------ Monetary Philade 1233 $10,000 6/25/2015 End AIDS lphia Locust Summit/AIDS Fight St. Education Philade Month 2015 lphia, PA 19107 ------------------------------------------------------------------------ Monetary Project 273 $40,000 3/13/2015 The Support Inform Ninth Partnership Street San Francis co, CA 94103 ------------------------------------------------------------------------ Monetary Project 273 $65,000 6/12/2015 Mission Inform Ninth Support for Street Project San Inform Francis co, CA 94103 ------------------------------------------------------------------------ Monetary Project P.O. Box $5,000 10/3/2015 Transitional Transi 4826 Supportive tions, Austin, Housing Inc. TX Programs 78765 ------------------------------------------------------------------------ Monetary Resourc 2701 $3,000 5/27/2015 Valor e Reagan Latino--HIV Center Street Prevention of Dallas, Program Dallas TX , Inc. 75219 ------------------------------------------------------------------------ Monetary San 2508 $20,000 8/3/2015 Creating Diego Histori Circles of Human c Care Dignit Decatur y Road Founda Suite tion 160 San Diego, CA 92106 ------------------------------------------------------------------------ Monetary Set 8035 E. $5,000 10/3/2015 Phenomenal Apart R.L. Woman Aiming Thornto Program Victor n Frwy. (PWP) iously Suite To 424 Elimat Dallas, e TX Diseas 75228 es ------------------------------------------------------------------------ Monetary Sexual 410 7th $30,000 12/22/2015 Peer Minori st SE Education: ty Washing Empowering Youth ton, DC young MSM Assist 20003 of color to ance end HIV. League (SMYAL ) DBA: Suppor ting and Mentor ing Youth Advoca tes and Leader s ------------------------------------------------------------------------ Monetary Shanti 730 Polk $15,000 7/14/2015 Shanti's Hep Projec Street C Pilot t, 3rd Expansion Inc. Floor of our HIV San Services Francis Program co, CA 94109 ------------------------------------------------------------------------ Monetary Someone 1950 $30,000 12/22/2015 Improving Cares Spectru Linkage to Inc Of m Care and Atlant Circle Retention a Ste. among A145 Transgender Mariett Women and a, GA Gender 30067 Nonconformi ng People Living with HIV Project title: Transformin g, Renewing and Unifying Transgender Health Project (TRUTH) ------------------------------------------------------------------------ Monetary Southwe 300 $5,000 9/3/2015 HIV Care in st Southwe a Safety Boulev st Net Clinic ard Bouleva Setting Family rd Health Kansas Care, City, Inc. KS 66103 ------------------------------------------------------------------------ Monetary Southwe 1101 N. $4,500 5/15/2015 Hepatitis C st Central Education Center Avenue, and Support For Suite for High- HIV/ 200 risk AIDS, phoenix Populations Inc. , AZ 85004 ------------------------------------------------------------------------ Monetary St 808 W. $40,000 3/10/2015 South L.A. Johns 58th Mobile Well Street Health--Pee Child Los r Navigator And Angeles Program for Family , CA PWID Living Center 90037 with HIV , Inc. and/or Hepatitis C ------------------------------------------------------------------------ Monetary St. 1111 $75,000 12/22/2015 FINISH THE Luke's Amsterd JOB: Roosev am Ave Providing elt New HCV care to Hospit York, current or al NY former IV Center 10025 drug users previously diagnosed through governmenta l testing programs. ------------------------------------------------------------------------ Monetary The 17 Davis $65,000 7/14/2015 Ensuring AIDS Blvd. Adequate Instit Suite Funding for ute 403 Domestic Tampa, HIV/AIDS FL and 33606 Hepatitis Programs ------------------------------------------------------------------------ Monetary The Hep 1325 S. $25,000 5/20/2015 Hepatitis C C Colorad Testing and Connec o Linkage to tion Blvd., Care B-302 Denver, CO 80222 ------------------------------------------------------------------------ Monetary The PO Box $39,000 3/13/2015 The Open Open 99243 Door: Peer Door, Pittsbu Support for Inc. rgh, PA HIV 15233 Engagement and Retention in Care ------------------------------------------------------------------------ Monetary The 85 $15,000 5/15/2015 Women's HIV Well Norman Treatment Projec Avenue, Advocacy t Suite 1 Development Brookly Program n, NY 11222 ------------------------------------------------------------------------ Monetary The 85 $15,000 7/21/2015 Charitable Well Norman Donation Projec Avenue, for Online t Suite 1 Resources Brookly and Program n, NY Evaluation/ 11222 Outcome Measurement ------------------------------------------------------------------------ Monetary The 8101 $5,000 7/15/2015 Personal Wright Cameron Disease House Rd., Management Wellne Suite for HIV/ ss 105 AIDS and Center Austin, HepC , Inc. TX Clients 78754 ------------------------------------------------------------------------ Monetary TPA 5050 N. $20,000 10/8/2015 Peer Health Networ Broadwa Navigation k y Suite Services Incorp 300 orated Chicago Test , IL Positi 60640 ve Aware Networ k ------------------------------------------------------------------------ Monetary TPA 5050 N. $26,056 12/22/2015 Youth Networ Broadwa Investment k y Suite Incorp 300 orated Chicago Test , IL Positi 60640 ve Aware Networ k ------------------------------------------------------------------------ Monetary Treatme 261 $40,000 5/21/2015 Case Studies nt Fifth Action Ave Group, Suite Inc. 2110 New York, NY 10016 ------------------------------------------------------------------------ Monetary Univers UCSF $7,500 8/27/2015 Mission- ity of Allianc Based Califo e Support of rnia Health UCSF San Project Alliance Franci 1855 Health sco Folsom Project Street, Services Ste. for People 670 Box Living With 0884 or at Risk San of HIV/AIDS Francis co, CA 94143 ------------------------------------------------------------------------ Monetary Univers 51 $7,500 10/23/2015 The ity of Goodman Cincinnati Cincin Drive Exchange nati Suite Project: A 100, Public P.O. Health Box Initiative 19970 Cincinn ati, OH 45219- 0970 ------------------------------------------------------------------------ Monetary US 1300 PA $1,000,000 10/23/2015 Sirturo Agency Avenue. Donation for , NW, Program--US Intern SA-44 AID ationa Rm 475- Agreement l J Develo Washing pment ton, DC 20523 ------------------------------------------------------------------------ Monetary Vermont P. O. $40,000 3/10/2015 Expansion of Commit Box Vermont's tee 5248 Services to For Burling Improve Aids ton, VT Care for Resour 05402 PWID Living ces with HCV Educat ion and Servic es ------------------------------------------------------------------------ Monetary Warren- 511 Ruin $28,800 12/22/2015 Online Vance Creek Linkage and Commun Rd STE Retention ity 105 Project for Health Henders YMSM Center on, NC , Inc. 27536 ------------------------------------------------------------------------ Monetary Washing 566 West $40,000 3/13/2015 Engaging ton 181st High Risk Height Street, Active s Floor 2 Injection CORNER New Drug Users Projec York, in t NY Hepatitis C 10033 testing and Treatment in Northern Manhattan ------------------------------------------------------------------------ Monetary Wellnes 2921 NE $5,000 7/15/2015 Sister-to- s 6th Ave Sister Center Wilton of Manors, South FL Florid 33334 a, Inc. ------------------------------------------------------------------------ Monetary WORLD 449 15th $15,000 12/17/2015 2nd CHANCE Women St., (Creating a Organi Suite Healthy and zed to 303 Nurturing Respon Oakland Community d to , CA Environment Life- 94612 ) threat ening Diseas es ------------------------------------------------------------------------ Product Johnson One $13,174,000 3/15/2013 Patient & Johnson Assistance Johnso & Product n Johnson Donation Patien Plaza, t New Assist Brunswi ance ck, NJ Founda 08933 tion ------------------------------------------------------------------------ Product Johnson One $6,019,000 6/15/2013 Patient & Johnson Assistance Johnso & Product n Johnson Donation Patien Plaza, t New Assist Brunswi ance ck, NJ Founda 08933 tion ------------------------------------------------------------------------ Product Johnson One $59,199,000 9/15/2013 Patient & Johnson Assistance Johnso & Product n Johnson Donation Patien Plaza, t New Assist Brunswi ance ck, NJ Founda 08933 tion ------------------------------------------------------------------------ Product Johnson One $4,718,000 12/15/2013 Patient & Johnson Assistance Johnso & Product n Johnson Donation Patien Plaza, t New Assist Brunswi ance ck, NJ Founda 08933 tion ------------------------------------------------------------------------ Updated March 24, 2016 Janssen Biotech, Inc. Monetary and Product Contribution to U.S.-based Charitable Organizations Full Year 2016 (Payments made from January 1, 2016 to December 31, 2016) ------------------------------------------------------------------------ Project Donation Payee Payee Payment Amount Payment Title/ Type Address (USD) Date Description ------------------------------------------------------------------------ Monetary Aid For 12271 $300 9/19/2016 Costs Friend Townsen associated s d Rd with 2016 Philade Janssen lphia, Cares PA Volunteer 19154 Activity ------------------------------------------------------------------------ Monetary America 2310 $1,500 4/11/2016 2016 Run for n Route Dad, Cancer 34, Awareness Societ Suite Sponsor y Inc. 1D Manasqu an, NJ 08736 ------------------------------------------------------------------------ Monetary America 1626 $1,000 4/15/2016 Relay For n Locust Life of the Cancer Street Wissahickon Societ Philade Valley y Inc. lphia, PA 19103 ------------------------------------------------------------------------ Monetary Arthrit 1355 $200,000 6/3/2016 Renewal is Peachtr support of Founda ee Arthritis tion Street, Foundation Suite Run / Walk 600 series - Atlanta Walk to , GA Cure 30309 Arthritis and Jingle Bell Run ------------------------------------------------------------------------ Monetary Arthrit 1355 $100,000 4/11/2016 General is Peachtr Operating Founda ee Support tion Street, Suite 600 Atlanta , GA 30309 ------------------------------------------------------------------------ Monetary Arthrit 2280 $75 3/7/2016 Employee is South directed Founda Albion donation in tion, Street lieu of Great Denver, company West CO holiday Region 80222- gift , Inc. 4906 ------------------------------------------------------------------------ Monetary Bicol 21019 $1,425 3/8/2016 Employee Founda 47th directed tion Ave W donation in Lynnwoo lieu of d, WA company 98036 holiday gift ------------------------------------------------------------------------ Monetary Cancer 200 Kirk $2,000 8/17/2016 Paws 4 Life Suppor Road PO Dog Walk t Box Commun 3187 ity of Warmins Philad ter, PA elphia 18974 ------------------------------------------------------------------------ Monetary Cancer 200 Kirk $2,500 8/30/2016 Celebration Suppor Road PO of Hope t Box Commun 3187 ity of Warmins Philad ter, PA elphia 18974 ------------------------------------------------------------------------ Monetary Cancer 200 Kirk $900 9/13/2016 Costs Suppor Road PO associated t Box with 2016 Commun 3187 Janssen ity of Warmins Cares Philad ter, PA Volunteer elphia 18974 Activity ------------------------------------------------------------------------ Monetary Cancer 944 $3,500 8/5/2016 Cancer Suppor Marcon Support and t Blvd., Education Commun #110 Allentown, ity of Allento PA the wn, PA Greate 18109 r Lehigh Valley ------------------------------------------------------------------------ Monetary Canine PO Box $300 9/14/2016 Costs Partne 170 associated rs for Cochran with 2016 Life ville, Janssen PA Cares 19330 Volunteer Activity ------------------------------------------------------------------------ Monetary Center 1900 $5,000 5/27/2016 Project for for Cherry Medically Child Street Needy Advoca Philade Children tes lphia, PA 19103 ------------------------------------------------------------------------ Monetary Childre CHOP $5,000 4/12/2016 7th Annual n's Foundat Walk for Hospit ion Hope al of ATTN: benefiting Philad Holly pediatric elphia Hubbard/ Inflammator Founda Walk y Bowel tion for Disease Hope Research 2016 PO Box 40930 34th and Civic Center Blvd. Philade lphia, NJ 19107 ------------------------------------------------------------------------ Monetary Communi 300B $20,000 12/14/2016 Free medical ty Lawrenc and dental Volunt e Drive care eers West services in Chester for Medici , PA uninsured ne 19380 families in Chester County ------------------------------------------------------------------------ Monetary Crohn's 733 $135,000 2/26/2016 Take Steps and Third 2016 Walk Coliti Avenue Program s Suite Founda 510 New tion York, of NY Americ 10017 a, Inc. ------------------------------------------------------------------------ Monetary Crohn's 733 $5,000 6/13/2016 Disease and Third State Coliti Ave, Awareness s Suite (DSA) Word Founda 510 New Cloud tion York, Activity of NY Americ 10017 a, Inc. ------------------------------------------------------------------------ Monetary Crohn's 733 $18,000 6/13/2016 Camp Oasis and Third Coliti Ave, s Suite Founda 510 New tion York, of NY Americ 10017 a, Inc.- NY Chapte r ------------------------------------------------------------------------ Monetary Delawar 236 $5,000 3/21/2016 Teacher e Randell Development Valley Hall Program Scienc 3141 e Chestnu Fairs, t Inc. Street Philade lphia, PA 19104 ------------------------------------------------------------------------ Monetary Doernbe 1121 SW $75 3/21/2016 Employee cher Salmon directed Childr St #100 donation in en's Portlan lieu of Hospit d, OR company al 97205 holiday Founda gift tion ------------------------------------------------------------------------ Monetary Family 142 $25,000 9/30/2016 Family Reach Reach Berkele Foundation Founda y General tion Street, Support 4th Floor Boston, MA 02116 ------------------------------------------------------------------------ Monetary Family 142 $250,000 12/22/2016 Family Reach Reach Berkele Programmati Founda y c Support tion Street; 4th Floor Boston, MA 02116 ------------------------------------------------------------------------ Monetary Food 1501 $5,000 12/15/2016 Year Round Bank John Youth of Tipton Feeding South Blvd Programs Jersey Pennsau ken Townshi p, NJ 08110 ------------------------------------------------------------------------ Monetary Friends 113 West $3,000 12/26/2016 Outreach to Associ Chestnu Homeless ation t Families For Street Care West and Chester Protec , PA tion 19380 Of Childr en ------------------------------------------------------------------------ Monetary Georgia 560 $1,700 4/12/2016 Free Prosta Barnesl Prostate te ey Lane Cancer Cancer Alphare Screening Coalit tta, GA ion 30022 Inc. ------------------------------------------------------------------------ Monetary Girl 330 $4,000 10/10/2016 Girl Scouts Scouts Manor of Eastern of Road Pennsylvani Southe Miquon, a Science, astern PA Technology, Pennsy 19444 Engineering lvania , and Math (STEM) programming . ------------------------------------------------------------------------ Monetary Green 1368 $15,000 12/15/2016 Watershed Valley Prizer Science s Road Education Associ Pottsto Program ation wn, PA 19465 ------------------------------------------------------------------------ Monetary Habitat 1847 E $2,000 5/30/2016 Building for Lincoln communities Humani Hwy and ty of Coatesv changing Cheste ille, lives r PA County 19320 , Inc. ------------------------------------------------------------------------ Monetary Habitat 1829 N. $300 11/3/2016 Costs For 19th associated Humani Street with 2016 ty Philade Janssen Philad lphia, Cares elphia PA Volunteer Inc. 19121 Activity ------------------------------------------------------------------------ Monetary Habitat 1829 N. $5,000 12/26/2016 Diamond Park For 19th Phase 2-- Humani Street affordable ty Philade housing Philad lphia, elphia PA Inc. 19121 ------------------------------------------------------------------------ Monetary Hatboro- 229 $25,000 12/14/2016 STEM Horsha Meeting Programs m house for Hatboro- Educat Road Horsham ional Horsham Students Founda , PA tion 19044 ------------------------------------------------------------------------ Monetary Horsham PO Box $1,000 8/5/2016 K9 Program Neighb 621 Fit Out and ors Horsham National Associ , PA Night Out ation 19044 Celebration ------------------------------------------------------------------------ Monetary Junior 994 Old $7,500 8/18/2016 Junior Achiev Eagle Achievement ement School Whole Of Rd School Delawa Suite Initiative re 1014 Valley Wayne, PA 19087 ------------------------------------------------------------------------ Monetary Kids 26071 $3,000 8/30/2016 Support Connec Merit Groups for ted Circle, the #103 Children of Laguna Cancer Hills, Patients CA 92653- 7016 ------------------------------------------------------------------------ Monetary Melanom 250 $100 9/30/2016 Memorial a Maplefl Donation Intern ower ationa Road l Glenmoo Founda re, PA tion 19343 ------------------------------------------------------------------------ Monetary Metropo 2323 $25,000 12/16/2016 Medically litan Ranstea Appropriate Area d Meals for Neighb Street People with orhood Philade Critical Nutrit lphia, Illnesses ion PA Allian 19103 ce (MANNA ) ------------------------------------------------------------------------ Monetary Mitzvah 1561 $300 9/22/2016 Costs Circle Gehman associated Founda Road with 2016 tion Harleys Janssen ville, Cares PA Volunteer 19438 Activity ------------------------------------------------------------------------ Monetary Mitzvah 1561 $5,000 8/5/2016 Critical Circle Gehman Needs Founda Road Support for tion Harleys Individuals ville, and PA Families 19438 ------------------------------------------------------------------------ Monetary Montgom 340 $10,000 12/9/2016 The Study of ery DeKalb Psychology County Pike as a Guide Commun Blue to Peer ity Bell, Mentorship Colleg PA for BTE-- e 19422 Wissahickon Founda tion ------------------------------------------------------------------------ Monetary Montgom 340 $23,811 12/9/2016 Bridge to ery DeKalb Employment- County Pike -Wissahicko Commun Blue n ity Bell, Colleg PA e 19422 Founda tion ------------------------------------------------------------------------ Monetary Mt. One $50,000 10/18/2016 Overcoming Sinai Gustave the Medica L. Levy Barriers to l Place Clinical Center Box Care for 1049 Underserved New Multiple York, Myeloma NY Patients 10029 ------------------------------------------------------------------------ Monetary Multipl 383 Main $50,000 12/22/2016 MMRF e Avenue Endurance Myelom 5th Events a Floor Resear Norwalk ch , CT Founda 06851 tion ------------------------------------------------------------------------ Monetary Multipl 383 Main $100,000 12/22/2016 2017 MMRF e Avenue Team for Myelom 5th Cures 5K a Floor Walk/Run Resear Norwalk Program ch , CT Founda 06851 tion ------------------------------------------------------------------------ Monetary Multipl 383 Main $275,000 12/22/2016 MMy Ride for e Avenue a Cure Myelom 5th a Floor Resear Norwalk ch , CT Founda 06851 tion ------------------------------------------------------------------------ Monetary Multipl 383 Main $40,000 12/23/2016 MMRF Patient e Avenue Support Myelom 5th Center a Floor Resear Norwalk ch , CT Founda 06851 tion ------------------------------------------------------------------------ Monetary Multipl 51 Locus $100,000 2/23/2016 2016 MMRF e Avenue Team for Myelom Suite Cures 5K a 201 Walk/Run Resear Norwalk Program ch , CT Founda 06851 tion ------------------------------------------------------------------------ Monetary Multipl 383 Main $50,000 3/7/2016 2016 MMRF e Avenue Team for Myelom 5th Cures a Floor Endurance Resear Norwalk Events ch , CT Program Founda 06851 tion ------------------------------------------------------------------------ Monetary Nationa 4950 $2,500 4/15/2016 Run/Walk to l York Break the Ovaria Rd, Silence on n Unit Ovarian Cancer 631 Cancer Coalit Holicon ion g, PA Inc. 18928 ------------------------------------------------------------------------ Monetary Nationa 6600 SW $50,000 5/3/2016 2016 Team l 92nd NPF Walk Psoria Ave., sis #300 Founda Portlan tion d, OR 97223 ------------------------------------------------------------------------ Monetary NET 499 N. $1,125 3/4/2016 Employee Treatm 5th directed ent St., donation in Servic Suite A lieu of es Philade company lphia, holiday PA gift 19123 ------------------------------------------------------------------------ Monetary Philade 1729 $75,000 12/27/2016 STEAM Mural lphia Mount Initiative Mural Vernon Arts Street Progra Philade m lphia, PA 19130 ------------------------------------------------------------------------ Monetary Project 1515 $1,000 12/16/2016 Mental HOME Fairmou Health and nt Recovery Avenue Services Philade lphia, PA 19130 ------------------------------------------------------------------------ Monetary Prostat 7009 S. $30,000 5/20/2016 Prostate e Potomac Cancer Cancer Street Disparities Educat Suite Outreach ion 125 Program Counci Centenn l ial, CO 80112 ------------------------------------------------------------------------ Monetary Prostat 500 $50,000 2/8/2016 Partnerships e Victory for Health Road Education, Educat Quincy, Support and ion MA Outreach Networ 02170 k Inc. ------------------------------------------------------------------------ Monetary Reach 89 South $5,000 12/21/2016 Preparing Out Street, Families and Suite for School Read 201 Success Boston, MA 02111 ------------------------------------------------------------------------ Monetary Rebuild 4355 $5,000 4/12/2016 Mantua Block ing Orchard Build 2016 Togeth Street er Suite Philad 2R elphia Philade lphia, PA 19124 ------------------------------------------------------------------------ Monetary Regiona 30 $100 6/10/2016 Memorial l Milesto Donation Hospic ne Road e and Danbury Home , CT Care 06810 Center ------------------------------------------------------------------------ Monetary Retired 901 East $7,000 5/23/2016 RSVP's and 8th America Senior Street Reads/ Volunt Suite Writes and eer 200 Protege One- Progra King of on-One m of Prussia Mentoring Montgo , PA Programs. mery 19406 County ------------------------------------------------------------------------ Monetary Retired 901 East $10,000 12/15/2016 RSVP's and 8th Family Senior Street Literacy Volunt Suite Volunteer eer 200 Program Progra King of (FLVP) and m of Prussia My Free Montgo , PA Tutor (MFT) mery 19406 virtual County STEM tutoring and career awareness Program. ------------------------------------------------------------------------ Monetary Riverbe 1950 $6,000 8/5/2016 Outreach to nd Spring Children/ Enviro Mill Access to nmenta Road Nature/ l Gladwyn Norristown Educat e, PA Area School ion 19035 District Center ------------------------------------------------------------------------ Monetary Sandy 2010 $2,000 12/14/2016 Sandy Sprint Rollma West Superhero n Chester 5K or 10K Ovaria Pike, Run/Walk n Suite Cancer 410 Founda Haverto tion, wn, PA Inc. 19083 ------------------------------------------------------------------------ Monetary SARC 24 Frank $9,500 9/22/2016 General Lloyd Operating Wright Support--We Drive A/ bsite 3100 PO Box 406 Ann Arbor, MI 48105 ------------------------------------------------------------------------ Monetary Special 2800 $300 9/22/2016 Costs Equest Street associated rians Road with 2016 P.O. Janssen Box Cares 1001 Volunteer Warring Activity ton, PA 18976 ------------------------------------------------------------------------ Monetary Special 2800 $4,000 10/10/2016 Special Equest Street Equestrians rians Road Equine- P.O. Assisted Box Learning 1001 and Warring Therapeutic ton, PA Riding 18976 Program ------------------------------------------------------------------------ Monetary Starfin 4015 $10,000 4/19/2016 Starfinder's der Main Soccer, Founda Street Education, tion Philade and lphia, Leadership PA Development 19127 Programs for Youth ------------------------------------------------------------------------ Monetary The The $12,000 4/19/2016 Family Care Childr Childre Binder en's n's Program Hospit Hospita al of l of Philad Philade elphia lphia Founda Foundat tion ion Attn: Staci Carney, Associa te Directo r, Corpora te and Foundat ion Relatio ns 100 Penn Square East 8th Floor, Suite 8050 Philade lphia, PA 19107 ------------------------------------------------------------------------ Monetary The The $5,000 4/12/2016 Child Life, Childr Childre Education, en's n's and Hospit Hospita Creative al of l of Arts Philad Philade Therapy elphia lphia Program Founda Foundat tion ion Attn: Staci Carney, Associa te Directo r, Corpora te and Foundat ion Relatio ns 100 Penn Square East 8th Floor, Suite 8050 Philade lphia, PA 19107 ------------------------------------------------------------------------ Monetary The 222 $10,000 12/26/2016 Corporate Frankl North Membership in 20th Instit St. ute Philade lphia, PA 19103 ------------------------------------------------------------------------ Monetary The 622 $2,000 8/18/2016 General Giving Evans Operating Tree Road PO Support Box 823 with an Gwynedd emphasis on Valley, the Public PA Educational 19437 Giving Events ------------------------------------------------------------------------ Monetary The 2600 $10,000 3/24/2016 Hubert J.P. Melmar Wayland Schoemaker k Road Classic Charit Berwyn, able PA Founda 19312 tion ------------------------------------------------------------------------ Monetary The 400 $600 9/19/2016 Costs Pennsb Pennsbu associated ury ry with 2016 Societ Memoria Janssen y l Road Cares Morrisv Volunteer ille, Activity PA 19067 ------------------------------------------------------------------------ Monetary The 775 E $9,500 8/5/2016 Sarcoma Sarcom Blithed Alliance a ale General Allian #334 Support ce Mill Valley, CA 94941 ------------------------------------------------------------------------ Monetary Trustee 3025 $5,000 12/26/2016 WXPN s Of Walnut Musicians The Street On Call Univer Philade sity lphia, Of PA Pennsy 19104 lvania ------------------------------------------------------------------------ Monetary Turning 415 $5,000 4/12/2016 Families and Points South Schools For 15th Together Childr Street (FAST) en Philade Program lphia, PA 19146 ------------------------------------------------------------------------ Monetary United 1709 $245,879 12/19/2016 Impact Fund Way of Benjami Greater Southe n Philadelphi astern Frankli a, PA and Pennsy n Southern, lvania Parkway NJ Philade lphia, PA 19103 ------------------------------------------------------------------------ Monetary Youth 949 $5,000 12/9/2016 The Youth Rally Chestnu Rally--a Commit t Oak camp for tee Dr St. kids/teens Inc. Charles living with , MO conditions 63303 affecting the bowel (Crohn's Disease and UC) and bladder systems. ------------------------------------------------------------------------ Monetary Zero 2000 $50,000 4/21/2016 ZERO The Joseph Prostate Projec E Cancer Run/ t To Sanker Walk End BLVD National Prosta Norwood Series--Nat te , OH ionwide Cancer 45212 ------------------------------------------------------------------------ Janssen has also made financial donations to independent charitable foundations that assist patients who are underinsured and in financial need with treatment-related expenses. In keeping with our donor agreements and applicable regulatory guidance, we will only disclose aggregate data on our charitable giving and do not publicize information on donations to specific foundations and disease states. In 2016, we contributed $47 million in donations to independent charitable foundations, enabling them to provide assistance with medication-related copays to patients with cancer and autoimmune diseases. ---------------------------------------------------------------------------------------------------------------- ---------------------------------------------------------------------------------------------------------------- Product Johnson & Johnson One Johnson & $71,016,839 3/31/2016 Patient Assistance Patient Assistance Johnson Plaza New Product Donation Foundation Brunswick, NJ 08933 ---------------------------------------------------------------------------------------------------------------- Product Johnson & Johnson One Johnson & $58,963,086 6/30/2016 Patient Assistance Patient Assistance Johnson Plaza New Product Donation Foundation Brunswick, NJ 08934 ---------------------------------------------------------------------------------------------------------------- Product Johnson & Johnson One Johnson & $60,107,176 9/30/2016 Patient Assistance Patient Assistance Johnson Plaza New Product Donation Foundation Brunswick, NJ 08935 ---------------------------------------------------------------------------------------------------------------- Product Johnson & Johnson One Johnson & 99,129,337 $12/31/2016 Patient Assistance Patient Assistance Johnson Plaza New Product Donation Foundation Brunswick, NJ 08936 ---------------------------------------------------------------------------------------------------------------- Updated March 30, 2017 Janssen Pharmaceuticals, Inc. Monetary and Product Contribution to U.S.- based Charitable Organizations Full Year 2016 (Payments made from January 1, 2016 to December 31, 2016) ------------------------------------------------------------------------ Project Donation Payee Payee Payment Amount Payment Title/ Type Address (USD) Date Description ------------------------------------------------------------------------ Monetary 180 1 $1,000 12/15/2016 2NDFLOOR Turnin Bethany Youth g Road, Helpline Lives Buildin Hunterdon, Around g 3 Mercer, and Inc. Suite Somerset 42 Operations Hazlet, NJ 07730 ------------------------------------------------------------------------ Monetary Alzheim 225 N. $5,000 12/15/2016 Comfort Zone er's Michiga Program Associ n Support ation Avenue Chicago , IL 60601 ------------------------------------------------------------------------ Monetary America 4100 $20,000 12/7/2016 General n Alpha mission Diabet Road, support es Suite Associ 100 ation Dallas, TX 75244 ------------------------------------------------------------------------ Monetary America 1160 $10,000 7/11/2016 What Can I n Route Eat? Diabet 22 es East, Associ Suite ation 103 Bridgew ater, NJ 08807 ------------------------------------------------------------------------ Monetary America PO Box $30,000 12/23/2016 Atrial n 541 Fibrillatio Founda Greenwo n Patient tion od, TX Education For 76246 and Support Womens Health ------------------------------------------------------------------------ Monetary America 1 Union $5,000 12/23/2016 Garden State n Street Go Red For Heart Suite Women Associ 301 Luncheon ation- Robbins -New ville, Jersey NJ 08691 ------------------------------------------------------------------------ Monetary America 1000 $100,000 12/15/2016 Typical or n Wilson Troubled? Psychi Blvd, School- atric Suite Based Founda 1825 Mental tion Arlingt Health on, VA Education 22209 Program ------------------------------------------------------------------------ Monetary America 1000 $200,000 12/15/2016 Judges' and n Wilson Psychiatris Psychi Blvd, ts' atric Suite Leadership Founda 1825 Initiative tion Arlingt previously on, VA known as 22209 Judges' Leadership Initiative (JLI) ------------------------------------------------------------------------ Monetary America 1000 $35,000 12/15/2016 Partnership n Wilson for Psychi Blvd, Workplace atric Suite Mental Founda 1825 Health tion Arlingt on, VA 22209 ------------------------------------------------------------------------ Monetary America 150 $300 9/27/2016 Costs 's Pittsto associated Grow-A- wn Road with 2016 Row, Pittsto Janssen Inc. wn, NJ Cares 08867 Volunteer Activity ------------------------------------------------------------------------ Monetary Anchor 482 $743 1/19/2016 General House, Centre Operating Inc. Street Support Trenton , NJ 08611 ------------------------------------------------------------------------ Monetary Anderso PO Box $20,000 12/7/2016 Integrated n 134 532 Care House Route Management 523 Whiteho use Station , NJ 08889 ------------------------------------------------------------------------ Monetary Ann 595 W. $9,500 12/15/2016 Improving Silver State Patient man Street Self-Care Commun Doylest and ity own, PA Management Health 18901 of Chronic Clinic Illnesses at a Free Clinic for the Uninsured. ------------------------------------------------------------------------ Monetary Arbor 211 $75 5/17/2016 Employee Day North directed Founda 12th St donation in tion Lincoln lieu of , NE company 68508 holiday gift ------------------------------------------------------------------------ Monetary Arc of 141 $3,000 9/28/2016 Day Care Somers South subsidies et Main for at risk County Street children Manvill and e, NJ children 08835 with disabilitie s ------------------------------------------------------------------------ Monetary Asian 180 W $2,000 4/6/2016 Cardiovascul Health Washing ar Health Coalit ton St Screenings ion Suite for Low- 1000 Income at- Chicago risk Asians , IL Immigrants 60602 and Refugees in Chicago ------------------------------------------------------------------------ Monetary Bay 66 Canal $5,000 6/24/2016 Bay Cove Cove Street Wellness Human Boston, Center Servic MA es, 02114 Inc. ------------------------------------------------------------------------ Monetary Bear 1162 $750 12/15/2016 The Bear Tavern Bear Tavern Parent Tavern Science s Road Fair Associ Titusvi ation lle, NJ 08560 ------------------------------------------------------------------------ Monetary Bear 1162 $750 3/1/2016 Bear Tavern Tavern Bear Elementary Parent Tavern School s Road Science Associ Titusvi Fair ation lle, NJ 08560 ------------------------------------------------------------------------ Monetary Big 2875 $6,500 11/18/2016 STEM School Brothe York Mentoring rs Big Road Initiative Sister Jamison s of , PA Bucks 18929 County ------------------------------------------------------------------------ Monetary Big 535 East $7,500 11/18/2016 Youth Brothe Frankli Mentoring rs Big n Programs Sister Street s of Trenton Mercer , NJ County 08610 ------------------------------------------------------------------------ Monetary Boys 212 $20,000 12/15/2016 Extended Day and Centre Learning Girls Street Club Trenton of , NJ Trento 08611 n and Mercer County ------------------------------------------------------------------------ Monetary Bristol 120 $7,500 12/15/2016 ArtRageous Rivers Radclif Theatre ide fe Arts Theate Street Education r Co Bristol Program Inc. , PA 19007 ------------------------------------------------------------------------ Monetary Broward 305 SE $15,000 8/4/2016 Affordable County 18th Housing Commun Court program ity Fort Develo Lauderd pment ale, FL Corpor 33316 ation , Inc. ------------------------------------------------------------------------ Monetary Bucks 1069 $5,000 12/15/2016 Veterans County Jackson Housing Housin ville Assistance g Road Program Group Ivyland , PA 18974 ------------------------------------------------------------------------ Monetary Califor 2015 $25,000 4/11/2016 Using nia Steiner Community Pacifi Street Health c San Workers to Medica Francis increase l co, CA underserved Center 94115 patients' Founda ability to tion manage type 2 diabetes. ------------------------------------------------------------------------ Monetary Caminar 2600 S. $7,500 4/12/2016 Bridges to El Wellness Camino Real, Suite 200 San Mateo, CA 94403 ------------------------------------------------------------------------ Monetary Cardiov PO Box $5,000 3/31/2016 25th Annual ascula 54632 Lansdale r Philade Internation Instit lphia, al Spring ute of PA Festival Philad 19148 elphia ------------------------------------------------------------------------ Monetary Catholi 25 Ikea $4,000 12/22/2016 Catholic c Drive Charities, Charit Westham Diocese of ies pton, Trenton On NJ My Own-- 08060 Supportive Housing Program Services ------------------------------------------------------------------------ Monetary Catholi 25 Ikea $15,000 12/22/2016 Partners in c Drive Recovery Charit Westham program ies pton, NJ 08060 ------------------------------------------------------------------------ Monetary Catholi 212 $75 1/19/2016 Employee c Ninth directed Charit Street donation in ies Pittsbu lieu of Dioces rgh, company e of Pennsyl holiday Pittsb vania gift urgh 15222 ------------------------------------------------------------------------ Monetary Catholi 920 $4,000 11/18/2016 CYO's Broad c South St. Trenton Youth Broad Center Organi Street After zation Trenton School of , NJ Program Mercer 08611 (ASP) County Tutoring Project ------------------------------------------------------------------------ Monetary Catholi 920 $600 10/19/2016 Costs c South associated Youth Broad with 2016 Organi Street Janssen zation Trenton Cares of , NJ Volunteer Mercer 08611 Activity--( County 2 Activities) ------------------------------------------------------------------------ Monetary Center 11 $10,000 10/24/2016 Community for Minneak Based Work Educat oning Assessments ional Road Advanc Fleming ement ton, NJ 08822 ------------------------------------------------------------------------ Monetary Center 11 $300 11/3/2016 Costs for Minneak associated Educat oning with 2016 ional Road Janssen Advanc Fleming Cares ement ton, NJ Volunteer 08822 Activity ------------------------------------------------------------------------ Monetary Childre 635 $300 11/19/2016 Costs n's South associated Home Clinton with 2016 Societ Avenue Janssen y of Trenton Cares New , NJ Volunteer Jersey 08611 Activity ------------------------------------------------------------------------ Monetary Childre 635 $10,000 11/22/2016 CUNA and n's South Body and Home Clinton Soul Societ Avenue Prenatal y of Trenton Health New , NJ Education Jersey 08611 Program ------------------------------------------------------------------------ Monetary Clevela 9500 $25,000 8/19/2016 Diabetes nd Euclid Center Clinic Ave. Educational Educat Clevela Initiatives ional nd, OH at Founda 44195 Cleveland tion Clinic South Pointe Hospital ------------------------------------------------------------------------ Monetary College 50 Milk $20,000 12/21/2016 Establishing Diabet St 16th Best es Floor Practices, Networ Boston, Policies, k Inc. MA and 02109 Interventio ns ------------------------------------------------------------------------ Monetary College 2000 $20,000 11/22/2016 Nursing of New Penning Merit Jersey ton Scholarship Road s ($7,500) P.O. and Box Educational 7718 Opportunity Ewing, Fund NJ Promise 08628 Awards ($12,500) ------------------------------------------------------------------------ Monetary College 2000 $5,000 11/22/2016 TCNJ Stress of New Penning Management Jersey ton and Mental Road Health Days P.O. Box 7718 Ewing, NJ 08628 ------------------------------------------------------------------------ Monetary Colorad 915 E. $3,000 8/9/2016 Wellness o 9th Recovery Mental Avenue Action Wellne Denver, Planning ss CO Program Networ 80218 k ------------------------------------------------------------------------ Monetary Communi PO Box $5,000 12/15/2016 Rise Summer ty 88 116 Healthy Action North Food Servic Main Initiative e Street for low Center Hightst income , Inc. own, NJ youth. 08520 ------------------------------------------------------------------------ Monetary Communi 4059 $5,000 3/1/2016 Arts for ty Skyron Seniors Conser Drive ($3,000) vatory Doylest and Music of own, PA Therapy Music 18902 ($2,000) ------------------------------------------------------------------------ Monetary Communi PO Box $250,000 12/21/2016 Janssen ty 338 Pharmaceuti Founda Morrist cal tion own, NJ Companies of New 07963 Contributio Jersey n Fund ------------------------------------------------------------------------ Monetary Communi PO Box $60,000 12/21/2016 HealtheVoice ty 338 s Impact Founda Morrist Fund tion own, NJ of New 07963 Jersey ------------------------------------------------------------------------ Monetary Communi PO Box $125,000 12/7/2016 Healthcare ty 338 and Basic Founda Morrist Needs Fund tion own, NJ of New 07963 Jersey ------------------------------------------------------------------------ Monetary Communi 315 $75 5/27/2016 Employee ty Losher directed Founda Street donation in tion Suite lieu of of 100 Company Northw Hernand Holiday est o, MS gift Missis 38632 sippi ------------------------------------------------------------------------ Monetary Communi 959 $2,000 3/10/2016 General ty Route Operating Hope, 46 Support Inc. East, Suite 402 Parsipp any, NJ 07054 ------------------------------------------------------------------------ Monetary Communi 959 $15,000 11/15/2016 Hope for ty Route Veterans Hope, 46 and Valley Inc. East, Brook Suite Village for 402 Veterans Parsipp any, NJ 07054 ------------------------------------------------------------------------ Monetary Communi 959 $11,000 5/16/2016 Pathway to ty Route Recovery Hope, 46 Residential Inc. East, Programs Suite ($10,000) 402 The Annual Parsipp Forum and any, NJ Wellness 07054 Fair ($1,000) ------------------------------------------------------------------------ Monetary Compeer 259 $2,500 5/30/2016 Youth and Roches Monroe Family ter, Avenue Mentoring-- Inc. Rochest Family Peer er, NY Advocate 14607 Services ------------------------------------------------------------------------ Monetary Contact 60 South $1,000 10/20/2016 Fundraising of Main event Mercer Street support to County Penning benefit New ton, NJ general Jersey 08534 mission of Inc. organizatio n ------------------------------------------------------------------------ Monetary Contact 60 South $8,500 12/15/2016 Crisis and Of Main Suicide Mercer Street Prevention County Penning HOTLINES, New ton, NJ Telephone Jersey 08534 and Online: Inc. Crisis Chat and TxtToday ------------------------------------------------------------------------ Monetary CONTACT P.O. Box $3,500 4/12/2016 Training We 2376 Nonprofessi Care, Westfie onals in Inc. ld, NJ Crisis 07091 Interventio n for People Experiencin g Psychosis ------------------------------------------------------------------------ Monetary Court 1450 $15,000 12/15/2016 CASA of Appoin Parksid Mercer ted e County Specia Avenue, Child l Suite Advocacy Advoca 22 Program for tes Ewing, Abused and NJ Neglected 08638- Children 2946 ------------------------------------------------------------------------ Monetary Curtain 1483 $5,000 12/19/2016 Deaf and Up Rte. Hard of Produc 179 Hearing tions Lambert Access for Inc. ville, Curtain Up NJ Productions 08530 ------------------------------------------------------------------------ Monetary Daytop 80 West $2,000 11/15/2016 Work Villag Main St Readiness e Of Mendham New , NJ Jersey 07945 Inc. ------------------------------------------------------------------------ Monetary Deborah 212 $2,000 11/14/2016 2017 Women's Hospit Trenton Heart al Road Health Founda Browns Symposium tion Mills, NJ 08015 ------------------------------------------------------------------------ Monetary Delawar 14 $300 10/19/2016 Costs e Michael associated River McCorri with 2016 Steamb stin Janssen oat Road Cares Floati Hamilto Volunteer ng n, NJ Activity Classr 08690 oom, Inc. ------------------------------------------------------------------------ Monetary Depress C/O $750 3/1/2016 DBSA NJ ion David Annual and Mizenko Conference Bipola 5 for Support r Village Group Suppor Ct Participant t Lawrenc s--July, Allian eville, 2016 ce NJ 08648 ------------------------------------------------------------------------ Monetary Depress C/O $750 3/1/2016 DBSA NJ ion David Mutual Aid and Mizenko Support Bipola 5 Group r Village Facilitator Suppor Ct Training--M t Lawrenc arch, 2016 Allian eville, ce NJ 08648 ------------------------------------------------------------------------ Monetary Desert 1695 N. $3,500 5/16/2016 Quality of Aids Sunrise Life and Projec Way Wellness t Palm Interventio Springs ns for , CA Desert AIDS 92262 Project Clients Living with Schizophren ia or Schizoaffec tive Disorder ------------------------------------------------------------------------ Monetary Diabete 319 N. $24,000 12/22/2016 Diabetes s Weber Sisters' Sister Road, Minority s pmb Initiative #163 Program Bolingb rook, IL 60490 ------------------------------------------------------------------------ Monetary Direct 27 S. La $4,600 2/18/2016 Support to Relief Patera improve the Lane lives of Santa people Barbara affected by , CA poverty or 93117 emergency situations by mobilizing and providing essential medical resources needed for their care ------------------------------------------------------------------------ Monetary Dress 3131 $9,000 10/11/2016 Women's for Princet Empowerment Succes on Pike Programs s Bldg 4; Suite 209 Lawrenc eville, NJ 08648 ------------------------------------------------------------------------ Monetary Eden 2 $9,500 12/15/2016 Adult Autism Merwick Employment Servic Road Program es Princet Founda on, NJ tion 08540 ------------------------------------------------------------------------ Monetary Emory 49 Jesse $25,000 10/24/2016 Emory Latino Univer Hill Diabetes sity Jr. Dr Education Atlanta Program , GA (ELDEP) 30303 ------------------------------------------------------------------------ Monetary Enable, 13 $3,000 9/12/2016 Fundraising Inc. Roszel event Road, support to Suite benefit B110 general Princet mission of on, NJ organizatio 08540 n ------------------------------------------------------------------------ Monetary Enable, 13 $7,500 12/15/2016 Enable Inc. 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Plantat County--Nov ion, FL ember 12, 33317 2016 ------------------------------------------------------------------------ Monetary NAMI 8324 $1,000 3/21/2016 Bronze Cook Skokie sponsor County Blvd NAMI CCNS North 420 Walk--Septe Suburb Frontag mber 18, an e Road 2016 Northfi eld Skokie, IL 60077 ------------------------------------------------------------------------ Monetary NAMI 2400 W. $1,000 3/15/2016 Bronze Delawa 4th St. sponsor re Wilming NAMIWalks ton, DE Delaware--M 19805 ay 7, 2016 ------------------------------------------------------------------------ Monetary NAMI 3371 $2,500 3/1/2016 Silver Mercer Brunswi sponsor NJ ck 2016 NAMI Pike, Mercer Suite Walk--May 124 7, 2016 Lawrenc eville, NJ 08648 ------------------------------------------------------------------------ Monetary NAMI 3371 $10,000 9/15/2016 NAMI Mercer Mercer Brunswi Education NJ ck and Support Pike, Programs Suite 124 Lawrenc eville, NJ 08648 ------------------------------------------------------------------------ Monetary NAMI 85 N. $1,000 9/7/2016 Bronze New State sponsor Hampsh Street 2016 ire Concord NAMIWalks , NH New 03301 Hampshire-- October 2, 2016 ------------------------------------------------------------------------ Monetary NAMI of 115 $8,000 8/9/2016 Peer Support DuPage North Specialist County County Program Illino Farm is Road Wheaton , IL 60187 ------------------------------------------------------------------------ Monetary NAMI of 2701 $4,000 8/24/2016 General Johnso Rochest Program n er Support/ County Avenue Finds dba Iowa Friends/ Compee City, Volunteer r of IA Recruitment Johnso 52245 n County ------------------------------------------------------------------------ Monetary NAMI of One $1,500 8/4/2016 Start to Lake Victori Finish County a Sq., sponsor Ste. 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Nationa 3839 $1,000 3/15/2016 Bronze l Merle sponsor Allian Hay NAMIWalks ce for Road, Iowa--Septe the Suite mber 24, Mental 226 Des 2016 ly Moines, Ill--I IA owa 50310 ------------------------------------------------------------------------ Monetary Nationa 505 8th $1,000 3/15/2016 Bronze l Avenue, sponsor Allian Ste NAMIWalks ce for 1103 NYC--May 7, the New 2016 Mental York, ly Ill NY of New 10018 York City ------------------------------------------------------------------------ Monetary Nationa 1981 $1,000 11/11/2016 Bronze l Marcus sponsor Allian Ave NAMIWalks ce for Suite Long Island/ the C117 Queens May Mental Lake 6, 2017 ly Ill Success Queens/ , NY Nassau 11042 ------------------------------------------------------------------------ Monetary Nationa 5963 $1,000 7/20/2016 Bronze l Boymel sponsor Allian Dr. NAMIWalks ce on Fairfie Butler Mental ld, OH County--Oct Illnes 45014 ober 8, s 2016 ------------------------------------------------------------------------ Monetary Nationa 324A $1,000 3/15/2016 NAMI Walk-- l Springf May 15, Allian ield 2016 ce on Street Mental Agawam, Illnes MA s 01001 Wester n Mass., Inc. ------------------------------------------------------------------------ Monetary Nationa P O Box $6,000 5/3/2016 29th Annual l Art 350891 NAEMI Art Exhibi Miami, Exhibition tions FL of the 33135 Mental ly Ill, Inc. ------------------------------------------------------------------------ Monetary Nationa 1400 K $75,000 12/15/2016 Policy l St NW, Action Counci #400 Center l for Washing Behavi ton, DC oral 20005 Health ------------------------------------------------------------------------ Monetary Nationa 1400 K $75,000 12/15/2016 Early Onset l St NW, Psychosis Counci #400 Community l for Washing of Practice Behavi ton, DC oral 20005 Health ------------------------------------------------------------------------ Monetary Nationa 1400 K $75,000 12/15/2016 Health l St NW, Justice Counci #400 Learning l for Washing Collaborati Behavi ton, DC ve oral 20005 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------------------------------------------------------------------------ Product Catholi 100 Wall $26,039,346 12/1/2016 Product c Street, donation Medica 9th for l Floor humanitaria Missio New n n York, assistance Board NY in 10005 Guatemala, Haiti, Dominican Republic, El Salvador. ------------------------------------------------------------------------ Product Catholi 100 Wall $248,988 12/1/2016 Product c Street, donation Medica 9th for l Floor humanitaria Missio New n n York, assistance Board NY in Haiti. 10005 ------------------------------------------------------------------------ Product Catholi 100 Wall $381,604 12/1/2016 Product c Street, donation Medica 9th for l Floor humanitaria Missio New n n York, assistance Board NY in Haiti 10005 and Dominican Republic. ------------------------------------------------------------------------ Product Catholi 100 Wall $361,008 12/1/2016 Product c Street, donation Medica 9th for l Floor humanitaria Missio New n n York, assistance Board NY in 10005 Guatemala and Haiti. ------------------------------------------------------------------------ Product Catholi 33-01 $76,321 9/13/2016 Product c Elevent donation Medica h for l Street humanitaria Missio Long n n Island assistance Board City, in Haiti. NY ------------------------------------------------------------------------ Product Catholi 100 Wall $622,686 10/25/2016 Product c Street, donation Medica 9th for l Floor humanitaria Missio New n n York, assistance Board NY in El 10005 Salvador, Guatemala ------------------------------------------------------------------------ Product Catholi 100 Wall $482,784 10/25/2016 Product c Street, donation Medica 9th for l Floor humanitaria Missio New n n York, assistance Board NY in El 10005 Salvador and Guatemala. ------------------------------------------------------------------------ Product Catholi 100 Wall $16,848,000 10/25/2016 Product c Street, donation Medica 9th for l Floor humanitaria Missio New n n York, assistance Board NY in 10005 Guatemala. ------------------------------------------------------------------------ Product Catholi 33-01 $822,943 9/22/2016 Product c Elevent donation Medica h for l Street humanitaria Missio Long n relief in n Island Honduras. Board City, NY ------------------------------------------------------------------------ Product Catholi 33-01 $139,387 9/22/2016 Product c Elevent donation Medica h for l Street humanitaria Missio Long n n Island assistance Board City, in NY Honduras. ------------------------------------------------------------------------ Product Catholi 33-01 $732,675 9/22/2016 Product c Elevent donation Medica h for l Street humanitaria Missio Long n n Island assistance Board City, in NY Honduras. ------------------------------------------------------------------------ Product Catholi 33-01 $76,696 9/13/2016 Product c Elevent donation Medica h for l Street humanitaria Missio Long n n Island assistance Board City, in Haiti. NY ------------------------------------------------------------------------ Product Catholi 33-01 $30,737 9/13/2016 Product c Elevent Donation Medica h for l Street humanitaria Missio Long n n Island assistance Board City, in Haiti. NY ------------------------------------------------------------------------ Product Catholi 33-01 $75,546 9/13/2016 Product c Elevent donation Medica h for l Street humanitaria Missio Long n n Island assistance Board City, in Haiti. NY ------------------------------------------------------------------------ Product Catholi 33-01 $270,923 9/13/2016 Product c Elevent donation Medica h for l Street humanitaria Missio Long n n Island assistance Board City, in Haiti. NY ------------------------------------------------------------------------ Product Catholi 33-01 $151,003 9/13/2016 Product c Elevent donation Medica h for l Street humanitaria Missio Long n n Island assistance Board City, in Haiti. NY ------------------------------------------------------------------------ Product Catholi 100 Wall $275,235 8/1/2016 Product c Street, donation Medica 9th for l Floor humanitaria Missio New n n York, assistance Board NY in 10005 Guatemala and Nicaragua. ------------------------------------------------------------------------ Product Catholi 100 Wall $48,005 8/1/2016 Product c Street, donation Medica 9th for l Floor humanitaria Missio New n n York, assistance Board NY in 10005 Guatemala and Nicaragua. ------------------------------------------------------------------------ Product Catholi 100 Wall $208,481 8/1/2016 Product c Street, donation Medica 9th for l Floor humanitaria Missio New n n York, assistance Board NY in 10005 Guatemala and Nicaragua. ------------------------------------------------------------------------ Product Catholi 100 Wall $1,162,207 8/1/2016 Product c Street, donation Medica 9th for l Floor humanitaria Missio New n n York, assistance Board NY in 10005 Guatemala and Nicaragua. ------------------------------------------------------------------------ Product Catholi 100 Wall $4,168 8/1/2016 Product c Street, donation Medica 9th for l Floor humanitaria Missio New n n York, assistance Board NY in Jamaica. 10005 ------------------------------------------------------------------------ Product Catholi 100 Wall $952,711 8/1/2016 Product c Street, donation Medica 9th for l Floor humanitaria Missio New n n York, assistance Board NY in 10005 Guatemala and Nicaragua. ------------------------------------------------------------------------ Product Catholi 33-01 $15,673 6/8/2016 Product c Elevent donation Medica h for l Street humanitaria Missio Long n n Island assistance Board City, in NY Nicaragua ------------------------------------------------------------------------ Product Catholi 33-01 $884,080 6/9/2016 Product c Elevent donation Medica h for l Street humanitaria Missio Long n n Island assistance Board City, in NY Nicaragua ------------------------------------------------------------------------ Product Catholi 33-01 $294,990 6/9/2016 Product c Elevent donation Medica h for l Street humanitaria Missio Long n n Island assistance Board City, in NY Nicaragua. ------------------------------------------------------------------------ Product Catholi 33-01 $97,026 5/10/2016 Product c Elevent donation Medica h for l Street humanitaria Missio Long n n Island assistance Board City, in NY Nicaragua ------------------------------------------------------------------------ Product Catholi 33-01 $137,045 5/10/2016 Product c Elevent donation Medica h for l Street humanitaria Missio Long n n Island assistance Board City, in NY Nicaragua ------------------------------------------------------------------------ Product Catholi 33-01 $561,881 5/10/2016 Product c Elevent donation Medica h for l Street humanitaria Missio Long n n Island assistance Board City, in Armenia, NY Guatemala, Honduras, El Salvador ------------------------------------------------------------------------ Product Catholi 33-01 $3,165,318 5/10/2016 Product c Elevent donation Medica h for l Street humanitaria Missio Long n n Island assistance Board City, in NY Dominican Republic, El Salvador, Haiti, Jamaica ------------------------------------------------------------------------ Product Catholi 33-01 $439,527 4/27/2016 Product c Elevent donation Medica h for l Street humanitaria Missio Long n n Island assistance Board City, in NY Dominican Republic, Haiti, Jamaica, Honduras ------------------------------------------------------------------------ Product Catholi 33-01 $864,289 4/27/2016 Product c Elevent donation Medica h for l Street humanitaria Missio Long n n Island assistance Board City, in NY Dominican Republic, Armenia, Haiti, Jamaica, El Salvador ------------------------------------------------------------------------ Product Direct 27 S. La $1,970,703 4/27/2016 Product Relief Patera donation Lane for Santa humanitaria Barbara n , CA assistance 93117 in Ecuador, Guatemala, Honduras, Liberia, Paraguay, Peru, Dominican Republic, Ghana, Haiti ------------------------------------------------------------------------ Product Direct 27 S. La $2,216,643 4/27/2016 Product Relief Patera donation Lane for Santa humanitaria Barbara n , CA assistance 93117 in Ghana, Honduras, Jordan, Liberia, Malawi, Paraguay, Peru, Sierra Leone, Guatemala, Haiti ------------------------------------------------------------------------ Product Direct 27 S. La $68,096 4/4/2016 Product Relief Patera donation Lane for Santa disaster Barbara preparednes , CA s module 93117 ------------------------------------------------------------------------ Product Direct 27 S. La $571,913 4/27/2016 Product Relief Patera donation Lane for Santa humanitaria Barbara n , CA assistance 93117 in Nicaragua, Malawi, Ghana, US ------------------------------------------------------------------------ Product Direct 27 S. La $1,270,853 4/27/2016 Product Relief Patera donation Lane for Santa humanitaria Barbara n , CA assistance 93117 in Colombia, Ghana, Guatemala, Honduras,. Jordan, Paraguay ------------------------------------------------------------------------ Product Direct 27 S. La $172,405 6/8/2016 Product Relief Patera donation Lane for Santa humanitaria Barbara n , CA assistance 93117 in Dominican Republic, Ghana, Pakistan, Paraguay. ------------------------------------------------------------------------ Product Direct 27 S. La $3,702,692 5/10/2016 Product Relief Patera donation Lane for Santa humanitaria Barbara n , CA assistance 93117 in Guyana, Armenia ------------------------------------------------------------------------ Product Direct 27 S. La $114,204 5/10/2016 Product Relief Patera donation Lane for Santa humanitaria Barbara n , CA assistance 93117 in Guyana ------------------------------------------------------------------------ Product Direct 27 S. La $4,350,366 6/9/2016 Product Relief Patera donation Lane for Santa humanitaria Barbara n , CA assistance 93117 in Dominican Republic, Ghana, Jamaica, Pakistan, Paraguay, Liberia, and Honduras ------------------------------------------------------------------------ Product Direct 27 S. La $2,620,434 6/9/2016 Product Relief Patera donation Lane for Santa humanitaria Barbara n , CA assistance 93117 in Ghana, Haiti, Paraguay, Somaliland, Dominican Republic, Honduras, Jamaica, Malawi, Pakistan, Rwanda. ------------------------------------------------------------------------ Product Direct 27 S. La $20,006 8/2/2016 Product Relief Patera donation Lane for Santa humanitaria Barbara n , CA assistance 93117 in Haiti. ------------------------------------------------------------------------ Product Direct 27 S. La $91,508 9/7/2016 Product Relief Patera donation Lane for Santa humanitaria Barbara n , CA assistance 93117 in the Dominican Republic. ------------------------------------------------------------------------ Product Direct 27 S. La $1,368,726 9/7/2016 Product Relief Patera donation Lane for Santa humanitaria Barbara n , CA assistance 93117 in Dominican Republic, Guyana, Fiji. ------------------------------------------------------------------------ Product Direct 27 S. La $30,737 9/7/2016 Product Relief Patera donation Lane for Santa humanitaria Barbara n , CA assistance 93117 in Nicaragua. ------------------------------------------------------------------------ Product Direct 27 S. La $812,768 9/7/2016 Product Relief Patera donation Lane for Santa humanitaria Barbara n , CA assistance 93117 in Dominican Republic. ------------------------------------------------------------------------ Product Direct 27 S. La $300,317 9/7/2016 Product Relief Patera donation Lane for Santa humanitaria Barbara n , CA assistance 93117 in Dominican Republic and Guyana. ------------------------------------------------------------------------ Product Direct 27 S. La $572,406 9/7/2016 Product Relief Patera donation Lane for Santa humanitaria Barbara n , CA assistance 93117 in Dominican Republic and Guyana. ------------------------------------------------------------------------ Product Direct 27 S. La $423,969 9/7/2016 Product Relief Patera donation Lane for Santa humanitaria Barbara n , CA assistance 93117 in Dominican Republic and Honduras. ------------------------------------------------------------------------ Product Direct 27 S. La $996,184 11/16/2016 Product Relief Patera donation Lane for Santa humanitaria Barbara n , CA assistance 93117 in Ghana ------------------------------------------------------------------------ Product Direct 27 S. La $159,065 11/16/2016 Product Relief Patera donation Lane for Santa humanitaria Barbara n , CA assistance 93117 in Ghana ------------------------------------------------------------------------ Product Direct 27 S. La $296,198 11/16/2016 Product Relief Patera donation Lane for Santa humanitaria Barbara n , CA assistance 93117 in Ghana ------------------------------------------------------------------------ Product Direct 27 S. La $113,778 11/16/2016 Product Relief Patera donation Lane for Santa humanitaria Barbara n , CA assistance 93117 in Ghana ------------------------------------------------------------------------ Product Direct 27 S. La $70,614 11/16/2016 Product Relief Patera donation Lane for Santa humanitaria Barbara n , CA assistance 93117 in Ghana ------------------------------------------------------------------------ Product Direct 27 S. La $56,506 11/16/2016 Product Relief Patera donation Lane for Santa humanitaria Barbara n , CA assistance 93117 in Ghana ------------------------------------------------------------------------ Product Direct 27 S. La $801,421 11/16/2016 Product Relief Patera donation Lane for Santa humanitaria Barbara n , CA assistance 93117 in Ghana ------------------------------------------------------------------------ Product Direct 27 S. La $720,416 11/16/2016 Product Relief Patera donation Lane for Santa humanitaria Barbara n , CA assistance 93117 in Ghana ------------------------------------------------------------------------ Product Direct 27 S. La $848,095 11/16/2016 Product Relief Patera donation Lane for Santa humanitaria Barbara n , CA assistance 93117 in Ghana ------------------------------------------------------------------------ Product Direct 27 S. La $22,144 5/10/2016 Product Relief Patera donation Lane for Santa humanitaria Barbara n , CA assistance 93117 in USA ------------------------------------------------------------------------ Product Direct 27 S. La $1,151,659 10/24/2016 Product Relief Patera donation Lane for Santa humanitaria Barbara n , CA assistance 93117 in Haiti, Ghana, Sierra Leone. ------------------------------------------------------------------------ Product Direct 27 S. La $1,781,473 10/24/2016 Product Relief Patera donation Lane for Santa humanitaria Barbara n , CA assistance 93117 in Honduras ------------------------------------------------------------------------ Product Direct 27 S. La $49,798 11/22/2016 Product Relief Patera donation Lane for Santa humanitaria Barbara n , CA assistance 93117 in Jamaica. ------------------------------------------------------------------------ Product Direct 27 S. La $18,947 11/22/2016 Product Relief Patera donation Lane for Santa humanitaria Barbara n , CA assistance 93117 in Peru and Nicaragua. ------------------------------------------------------------------------ Product Direct 27 S. La $21,529 11/22/2016 Product Relief Patera donation Lane for Santa humanitaria Barbara n , CA assistance 93117 in Peru. ------------------------------------------------------------------------ Product Direct 27 S. La $152,642 11/22/2016 Product Relief Patera donation Lane for Santa humanitaria Barbara n , CA assistance 93117 in Jamaica and Nicaragua. ------------------------------------------------------------------------ Product Direct 27 S. La $244,221 11/22/2016 Product Relief Patera donation Lane for Santa humanitaria Barbara n , CA assistance 93117 in Jamaica, Guatemala, Colombia, Nicaragua ------------------------------------------------------------------------ Product Direct 27 S. La $54,936 11/22/2016 Product Relief Patera donation Lane for Santa humanitaria Barbara n , CA assistance 93117 in Peru, Nicaragua and Colombia. ------------------------------------------------------------------------ Product Direct 27 S. La $86,941 12/22/2016 Product Relief Patera donation Lane for Santa humanitaria Barbara n , CA assistance 93117 in Honduras and Afghanistan . ------------------------------------------------------------------------ Product Direct 27 S. La $381,882 12/22/2016 Product Relief Patera donation Lane for Santa humanitaria Barbara n , CA assistance 93117 in Haiti, Afghanistan , Honduras. ------------------------------------------------------------------------ Product Direct 27 S. La $64,354 12/22/2016 Product Relief Patera donation Lane for Santa humanitaria Barbara n , CA assistance 93117 in US ------------------------------------------------------------------------ Product Direct 27 S. La $145,709 12/22/2016 Product Relief Patera donation Lane for Santa humanitaria Barbara n , CA assistance 93117 in US ------------------------------------------------------------------------ Product Direct 27 S. La $57,146 12/22/2016 Product Relief Patera donation Lane for Santa humanitaria Barbara n , CA assistance 93117 in Lebanon and Honduras. ------------------------------------------------------------------------ Product Direct 27 S. La $53,183 12/22/2016 Product Relief Patera donation Lane for Santa humanitaria Barbara n , CA assistance 93117 in Afghanistan . ------------------------------------------------------------------------ Product Direct 27 S. La $45,277 12/22/2016 Product Relief Patera donation Lane for Santa humanitaria Barbara n , CA assistance 93117 in Afghanistan and Honduras. ------------------------------------------------------------------------ Product Direct 27 S. La $203,883 12/22/2016 Product Relief Patera donation Lane for Santa humanitaria Barbara n relief in , CA Honduras 93117 and US. ------------------------------------------------------------------------ Product Direct 27 S. La $241,908 12/22/2016 Product Relief Patera donation Lane for Santa humanitaria Barbara n , CA assistance 93117 in Haiti and US ------------------------------------------------------------------------ Product Direct 27 S. La $102,180 12/22/2016 Product Relief Patera donation Lane for Santa humanitaria Barbara n , CA assistance 93117 in the US ------------------------------------------------------------------------ Product Direct 27 S. La $126,300 12/22/2016 Product Relief Patera donation Lane for Santa humanitaria Barbara n , CA assistance 93117 in Haiti. ------------------------------------------------------------------------ Product Direct 27 S. La $8,017 11/28/2016 Product Relief Patera donation Lane for Santa humanitaria Barbara n , CA assistance 93117 in Peru. ------------------------------------------------------------------------ Product Direct 27 S. La $179,712 12/19/2016 Product Relief Patera donation Lane for Santa humanitaria Barbara n , CA assistance 93117 in Malawi. ------------------------------------------------------------------------ Product Heart 13250 W $8,017 11/28/2016 Product To 98th donation Heart Street for Intern Lenexa, humanitaria ationa KS n l 66215 assistance in Honduras. ------------------------------------------------------------------------ Product Heart 13250 W $199,190 11/28/2016 Product To 98th donation Heart Street for Intern Lenexa, humanitaria ationa KS n l 66215 assistance in Haiti. ------------------------------------------------------------------------ Product Heart 13250 W $190,802 11/28/2016 Product To 98th donation Heart Street for Intern Lenexa, humanitaria ationa KS n l 66215 assistance in Honduras ------------------------------------------------------------------------ Product Heart 13250 W $83,392 11/28/2016 Product To 98th donation Heart Street for Intern Lenexa, humanitaria ationa KS n l 66215 assistance in Dominican Republic, Honduras. ------------------------------------------------------------------------ Product Heart 13250 W $635,226 9/26/2016 Product To 98th donation Heart Street for Intern Lenexa, humanitaria ationa KS n l 66215 assistance in Haiti. ------------------------------------------------------------------------ Product Heart 13250 W $194,454 9/16/2016 Product To 98th donation Heart Street for Intern Lenexa, humanitaria ationa KS n l 66215 assistance in Haiti and Guatemala ------------------------------------------------------------------------ Product Heart 13250 W $1,327,428 9/16/2016 Product To 98th donation Heart Street for Intern Lenexa, humanitaria ationa KS n l 66215 assistance in Haiti, Guatemala and Honduras. ------------------------------------------------------------------------ Product Heart 13250 W $114,481 9/16/2016 Product To 98th donation Heart Street for Intern Lenexa, humanitaria ationa KS n l 66215 assistance in Haiti. ------------------------------------------------------------------------ Product Heart 13250 W $61,475 9/16/2016 Product To 98th donation Heart Street for Intern Lenexa, humanitaria ationa KS n l 66215 assistance in Guatemala and El Salvador. ------------------------------------------------------------------------ Product Heart 13250 W $128,184 9/16/2016 Product To 98th donation Heart Street for Intern Lenexa, humanitaria ationa KS n l 66215 assistance in Haiti and Guatemala. ------------------------------------------------------------------------ Product Heart 1021 $148,499 6/9/2016 Product to Pacific donation Heart Avenue for Intern Kansas humanitaria ationa City, n l KS assistance 66102 in Dominican Republic, Guatemala, Jamaica ------------------------------------------------------------------------ Product Heart 1021 $31,346 6/8/2016 Product to Pacific donation Heart Avenue for Intern Kansas humanitaria ationa City, n l KS assistance 66102 in Guatemala, Jamaica. ------------------------------------------------------------------------ Product Heart 13250 W $963,188 5/10/2016 Product To 98th donation Heart Street for Intern Lenexa, humanitaria ationa KS n l 66215 assistance in Dominican Republic ------------------------------------------------------------------------ Product Heart 13250 W $808,425 5/10/2016 Product To 98th donation Heart Street for Intern Lenexa, humanitaria ationa KS n l 66215 assistance in Swaziland ------------------------------------------------------------------------ Product Johnson One $84,928,778 3/31/2016 Patient and Johnson Assistance Johnso & Product n Johnson Donation Patien Plaza t New Assist Brunswi ance ck, NJ Founda 08933 tion ------------------------------------------------------------------------ Product Johnson One $86,415,842 6/31/2016 Patient & Johnson Assistance Johnso & Product n Johnson Donation Patien Plaza t New Assist Brunswi ance ck, NJ Founda 08934 tion ------------------------------------------------------------------------ Product Johnson One $68,286,613 9/30/2016 Patient & Johnson Assistance Johnso & Product n Johnson Donation Patien Plaza t New Assist Brunswi ance ck, NJ Founda 08935 tion ------------------------------------------------------------------------ Product Johnson One $77,655,085 12/31/2016 Patient & Johnson Assistance Johnso & Product n Johnson Donation Patien Plaza t New Assist Brunswi ance ck, NJ Founda 08936 tion ------------------------------------------------------------------------ Product MAP 4700 $168,361 10/21/2016 Product Intern Glynco donation ationa Parkway for l Brunswi disaster ck, GA response in 31525 Haiti. ------------------------------------------------------------------------ Product MAP 4700 $35,275 11/28/2016 Product Intern Glynco donation ationa Parkway for l Brunswi humanitaria ck, GA n 31525 assistance in Central America. ------------------------------------------------------------------------ Product MAP 4700 $1,600,598 12/14/2016 Product Intern Glynco donation ationa Parkway for l Brunswi Humanitaria ck, GA n 31525 assistance in Dominican Republic. ------------------------------------------------------------------------ Product MAP 4700 $1,816 12/14/2016 Product Intern Glynco donation ationa Parkway for l Brunswi humanitaria ck, GA n 31525 assistance in Dominican Republic ------------------------------------------------------------------------ Product MAP 50 Hurt $1,471,357 12/16/2016 Product Intern Plaza donation ationa Atlanta for l , GA humanitaria 30303 n assistance in Dominican Republic ------------------------------------------------------------------------ Updated March 30, 2017 Janssen Therapeutics, Division of Janssen Products, LP, Monetary and Product Contribution to U.S.-based Charitable Organizations Full Year 2016 (Payments made from January 1, 2016 to December 31, 2016) ------------------------------------------------------------------------ Project Donation Payee Payee Payment Amount Payment Title/ Type Address (USD) Date Description ------------------------------------------------------------------------ Monetary Acercam 827 $7,500 4/25/2016 ContraSIDA iento Wildwoo (Against Hispan d Ave, HIV/AIDS) o de Suite Caroli 200 na del Columbi Sur a, SC 29203 ------------------------------------------------------------------------ Monetary ADAP 312 11th $5,000 6/1/2016 Improving Advoca Avenue, Access to cy #21g Care Among New Transgender York, Men and NY Women 10001 Living with HIV/AIDS under the AIDS Drug Assistance Program (ADAP) ------------------------------------------------------------------------ Monetary ADAP 312 11th $5,000 2/29/2016 ADAP Advoca Avenue, Directory cy #21g New York, NY 10001 ------------------------------------------------------------------------ Monetary African- 1833 W. $200,000 12/6/2016 Certificatio Americ 8th n of the an St., U.S. HIV Aids Suite Workforce: Policy 200 Los A Project And Angeles to Increase Traini , CA HIV ng 90057 Literacy Instit and ute Competency ------------------------------------------------------------------------ Monetary AIDS 600 St. $26,700 8/24/2016 (RFA)--Healt Action Clair hy Start Coalit Avenue ion of P.O. Huntsv Box ille 2409 Huntsvi lle, AL 35801 ------------------------------------------------------------------------ Monetary AIDS 75 Amory $30,000 12/6/2016 Getting to Action Street Zero MA Commit Boston, tee of MA Massac 02119 husett s ------------------------------------------------------------------------ Monetary Aids 575 8th $15,000 7/13/2016 HIV Health Commun Ave, Literacy ity Suite Education Resear 502 New and ch York, Training Initia NY for Service tive 10018 Providers of Working Americ with a Vulnerable ACRIA Populations ------------------------------------------------------------------------ Monetary AIDS 200 W. $48,000 6/21/2016 Ensuring Founda Jackson Access to tion Blvd HIV of Suite Prevention Chicag 2100 and Care in o Chicago Illinois , IL through 60606 Policy Monitoring and Advocacy ------------------------------------------------------------------------ Monetary AIDS 400 N $5,000 2/29/2016 HIV Case Outrea Beach Management ch Street at AIDS Center Fort Outreach Worth, Center TX 76111 ------------------------------------------------------------------------ Monetary AIDS The $7,500 12/14/2016 HIV Access Projec David and Care t Los Geffen Coordinatio Angele Center n Program s 611 S. Kingsle y Dr. Los Angeles , CA 90005 ------------------------------------------------------------------------ Monetary AIDS 64 West $20,000 6/21/2016 Peer Servic 35th Education, e Street, Health Center 3rd Coaching, NYC Floor and Access New to Care York, programs NY 10001 ------------------------------------------------------------------------ Monetary AIDS P.O. Box $30,000 8/24/2016 (RFA)--Posit Servic 169 121 ive Living es College Coalit Street ion Hatties burg, MS 39401 ------------------------------------------------------------------------ Monetary AIDS 17982 $5,000 12/16/2016 HIV and Servic Sky Hepatitis C es Park Testing Founda Circle, Program tion Suite J Orange Irvine, County CA 92614 ------------------------------------------------------------------------ Monetary AIDS 17982 $5,000 2/29/2016 HIV and Servic Sky Hepatitis C es Park Testing Founda Circle, Program tion Suite J Orange Irvine, County CA 92614 ------------------------------------------------------------------------ Monetary AIDS 7215 $5,000 1/18/2016 HIV Case Servic Cameron Management es of Road Austin Austin, Inc. TX 78752 ------------------------------------------------------------------------ Monetary AIDS 7215 $2,500 12/14/2016 Palateria Servic Cameron Cart es of Road Austin Austin, Inc. TX 78752 ------------------------------------------------------------------------ Monetary AIDS 7215 $30,000 8/8/2016 (RFA)--Risin Servic Cameron g Star es of Road University Austin Austin, Inc. TX 78752 ------------------------------------------------------------------------ Monetary AIDS 1424 K $300,000 12/19/2016 Transgender United Street, Leadership NW Demonstrati Suite on Project 200 Washing ton, DC 20005-2 411 ------------------------------------------------------------------------ Monetary Alexian 825 W. $5,000 6/20/2016 Transitional Brothe Welling Living rs ton Program for Bonave Chicago Homeless nture , IL Adults with House 60657 HIV/AIDS ------------------------------------------------------------------------ Monetary Allianc 825 $3,000 12/14/2016 Continuum-of- e For Colorad Care Housin o Services g And Blvd., for Multi- Healin Suite Diagnosed g 100 Los Persons Angeles with HIV/ , CA AIDS 90041 ------------------------------------------------------------------------ Monetary America Greater $3,000 8/25/2016 Ask the n New Experts: Liver York Hepatitis C/ Founda Divisio HIV Co- tion n 39 infection Broadwa Seminar y Suite 2700 New York, NY 10006 ------------------------------------------------------------------------ Monetary Atlanta P.O. Box $15,000 2/16/2016 Hepatitis C Harm 92670 Prevention Reduct Atlanta Program ion , GA Coalit 30314 ion ------------------------------------------------------------------------ Monetary Bienest 5326 E $25,000 12/6/2016 Bienestar ar Beverly HIV Blvd Programs Los and Angeles Services , CA 90022 ------------------------------------------------------------------------ Monetary Brother 2714 $28,500 8/24/2016 (RFA)--EMPOW hood, Canal ER NOLA Inc. Street Suite 503A New Orleans , LA 70119 ------------------------------------------------------------------------ Monetary Caring PO Box $40,000 3/24/2016 Hepatitis C Ambass 1748 Program adors Oregon Support--SH Progra City, APE and m Inc. OR CHOICES 97045 ------------------------------------------------------------------------ Monetary Catholi 119 $5,000 3/14/2016 The Home c Dameron Place Charit Avenue ies of Knoxvil East le, TN Tennes 37917 see Inc. ------------------------------------------------------------------------ Monetary Central 1785 $5,000 2/29/2016 Free On-Site Louisi Jackson Neighborhoo ana Street d Testing, Aids Alexand Counseling, Suppor ria, LA and t 71301 Prevention Servic Program es Inc. (CLASS ) ------------------------------------------------------------------------ Monetary Christi 2440 $10,000 7/13/2016 Integrated e's Third Services Place Ave San for Women, Inc. Diego, Children CA and 92101 Families ------------------------------------------------------------------------ Monetary Christi 2440 $20,000 2/18/2016 CHANGE for e's Third Women Place Ave San Inc. Diego, CA 92101 ------------------------------------------------------------------------ Monetary Coaliti 127 W $50,000 12/6/2016 Strengthenin on On 127th g Patient Positi Street Education ve Suite through Health 208 New Technology Empowe York, and Social rment NY Media Inc. 10027 ------------------------------------------------------------------------ Monetary Coastal 5633 $15,000 10/7/2016 HEP: Bend South Hepatitis Wellne Staples Education ss , Suite Program Founda 700 tion Corpus Christi , TX 78411 ------------------------------------------------------------------------ Monetary Communi 714 East $5,000 6/24/2016 Patient ty Sahara Wellness Counse Ave. Education ling Suite Center 103 Las Vegas, NV 89104 ------------------------------------------------------------------------ Monetary Communi 2409 $29,633 8/24/2016 (RFA)--Safe ty Murchis Spaces Health on Rd Ambassador Interv Fayette Program ention ville, s and NC Sickle 28301 Cell Agency Incorp orated ------------------------------------------------------------------------ Monetary Communi 60 $30,000 2/29/2016 Transgender ty Madison Linkage to Health Avenue, Care care 5th Networ floor k New York, NY 10010 ------------------------------------------------------------------------ Monetary Compreh 142 S. $25,000 8/24/2016 (RFA)--Proje ensive Brunswi ct IRIS Aids ck (Improving Resour Street Retention ce Suite B In the Encoun P.O. South) ter Box 552 Inc. Jesup, GA 31545 ------------------------------------------------------------------------ Monetary Crisis 1218 $75 7/12/2016 Employee Shelte West directed r of State donation in Lawren Street lieu of ce New company County Castle, holiday PA gift 16101- 2021 ------------------------------------------------------------------------ Monetary Desert 1695 N. $5,000 6/1/2016 Get Tested AIDS Sunrise Coachella Projec Way Valley t Palm Linkage to Springs Care for , CA Newly 92262 Diagnosed HIV- Positive Persons ------------------------------------------------------------------------ Monetary Frannie 30 $5,000 9/13/2016 Integrated Peabod Danfort Access to y h St. Care for Center Suite People Inc. 311 Living with Portlan HIV/AIDS d, ME 04101 ------------------------------------------------------------------------ Monetary Harm 22 West $25,000 7/13/2016 Hepatitis C Reduct 27th Project ion Street Coalit 5th ion Floor New York, NY 10001 ------------------------------------------------------------------------ Monetary Health 1211 $5,000 12/14/2016 Pennsylvania Federa Chestnu Ryan White tion t Part C/D Of Street, Collaborati Philad Suite ve elphia 801 Philade lphia, PA 19107 ------------------------------------------------------------------------ Monetary HealthH 2000 S $30,000 2/18/2016 Do You Know IV Street Me?: NW Engaging Washing and ton, DC Retaining 20009 Young MSM of Color in HIV Care ------------------------------------------------------------------------ Monetary Heart 3600 $5,000 3/16/2016 BROTHA--Brot Health Broadwa hers and y West Responding Healin Palm Openly to g Beach, HIV/AIDS Minist FL (Ujima ries 33407 Men's Inc. Collective) ------------------------------------------------------------------------ Monetary Hepatit 35 East $22,000 2/18/2016 The is C 38th Hepatitis C Mentor Street, Education And Suite and Support Suppor #4G New Group t York, Assistance Group NY Program Inc. 10016 ------------------------------------------------------------------------ Monetary Hepatit 1261 S. $35,000 3/14/2016 Case is Jackson management Educat St. ($25,000); ion Suite King County Projec 201 Jail t Seattle Hepatitis , WA Education 98144 ($10,000) ------------------------------------------------------------------------ Monetary Hepatit 8121 $5,000 5/6/2016 Call To is Georgia Action: A Founda Avenue National tion Suite Response Intern 350 for ationa Silver Hepatitis C l Inc. Spring, Treatment MD among the 20910 Hard to Reach, Hard to Treat. Proposal ------------------------------------------------------------------------ Monetary Jackson P.O. Box $30,000 8/8/2016 (RFA)--#AIDS ville 380103 FreeJax Area Jackson Linkage to Sexual ville, Care (L2C) Minori FL Program--a ty 32205 Comprehensi Youth ve HIV/AIDS Networ Linkage to k, Care Inc. Program for (JASMY African N) American YMSM, ages 13-23 ------------------------------------------------------------------------ Monetary Legacy 4054 $5,000 12/14/2016 Legacy Counse McKinne Counseling ling y Center Center Avenue Counseling Suite and Walk-In 102 Crisis Dallas, Clinic TX Program for 75204 People Living with HIV/AIDS ------------------------------------------------------------------------ Monetary Make-A- 2880 $450 2/8/2016 Employee Wish Slater directed Founda Road, donation in tion Suite lieu of of 108 company Easter Morrisv holiday n ille, gift North NC Caroli 27560 na ------------------------------------------------------------------------ Monetary MCCNY 446 West $10,000 12/6/2016 Linkage to Charit 36th Care for ies Street LGBTQI New Homeless York, Youth NY 10018 ------------------------------------------------------------------------ Monetary Minorit 5149 W. $7,500 4/12/2016 The Missing y AIDS Jeffers Link Projec on Blvd ``G.L.A.M.O t Los .R.'' Angeles (Getting , CA Linked And 90016 Managing Our Regimen) ------------------------------------------------------------------------ Monetary Missour 601 $9,650 8/9/2016 Hep C i Busines Education Hepati s Loop and tis C 70 West Testing--Th Allian Suite e Texas ce 138 Project Columbi a, MO 65203 ------------------------------------------------------------------------ Monetary Nationa 580 $175,000 3/7/2016 NATAP HIV l AIDS Broadwa and HCV Treatm y Suite Information ent 1010 and Advoca New Education cy York, Project Projec NY t 10012 ------------------------------------------------------------------------ Monetary Nationa 444 N. $150,000 12/19/2016 Health l Capitol Systems Allian St., NW Integration ce of Suite , Ryan State 339 White/ADAP, and Washing and Viral Territ ton, DC Hepatitis orial 20001 Public AIDS Policy and Direct Technical ors Assistance Programs ------------------------------------------------------------------------ Monetary Nationa 1000 $50,000 12/15/2016 Strong l Vermont Communities Minori Avenue : Social ty NW Drivers of AIDS Suite HIV Counci 200 l Washing ton, DC 20005 ------------------------------------------------------------------------ Monetary Nationa 1000 $30,000 2/16/2016 Strong l Vermont Communities Minori Avenue : ty NW Strengtheni AIDS Suite ng Counci 200 connections l Washing between ton, DC LGBT 20005 communities of color and the providers that serve them ------------------------------------------------------------------------ Monetary New 44 South $5,000 2/29/2016 Community Jersey Street Based AIDS Morrist Services Servic own, NJ es 07960 ------------------------------------------------------------------------ Monetary Next 99 $5,000 6/20/2016 Expansion of Step Bishop Next Step's Fund Allen Year-round Inc. Drive Programming Cambrid for teens ge, MA and young 02139 adults living with HIV. ------------------------------------------------------------------------ Monetary Our 2727 SE $5,000 8/23/2016 Neighborhood House Alder Housing and of St. Care Portla Portlan Program nd d, OR (NHCP) Incorp 97214 orated ------------------------------------------------------------------------ Monetary Palmett 2638 Two $7,500 5/6/2016 HIV Care o AIDS Notch Coordinatio Life Road, n Program Suppor Suite t 108 Servic Columbi es a, SC 29204 ------------------------------------------------------------------------ Monetary Positiv 785 $2,500 12/16/2016 Employment e Market and Resour Street, Benefits ce 10th Education Center Floor San Francis co, CA 94103 ------------------------------------------------------------------------ Monetary Project 273 $60,000 10/6/2016 Policy Inform Ninth Initiatives Street to Improve San Access to Francis Care and co, CA Treatment 94103 ------------------------------------------------------------------------ Monetary Project 273 $20,000 7/15/2016 Hepatitis C Inform Ninth Education Street and Linkage San to Care Francis co, CA 94103 ------------------------------------------------------------------------ Monetary Project 273 $30,000 12/19/2016 The Support Inform Ninth Partnership Street San Francis co, CA 94103 ------------------------------------------------------------------------ Monetary Project 273 $70,000 5/19/2016 Mission Inform Ninth Support for Street Project San Inform Francis co, CA 94103 ------------------------------------------------------------------------ Monetary Project 273 $40,000 2/18/2016 The Support Inform Ninth Partnership Street San Francis co, CA 94103 ------------------------------------------------------------------------ Monetary RAIN, 601 E. $30,000 8/8/2016 (RFA)--Impro Inc. 5th ving Street, Retention Suite in Care and 470 Access to Charlot Treatment te, NC for African 28202 Americans Living with HIV in Charlotte Metropolita n area ------------------------------------------------------------------------ Monetary RAIN, 601 E. $5,000 4/25/2016 Medical Case Inc. 5th Management Street, for Youth, Suite Adults and 470 Seniors Charlot with HIV/ te, NC AIDS 28202 ------------------------------------------------------------------------ Monetary Recover 3423 $75,000 4/15/2016 The Healthy y Covingt Start Consul on Program tants Drive, Of Suite B Atlant Decatur a , GA Incorp 30032 orated ------------------------------------------------------------------------ Monetary Resourc 5750 $3,000 12/14/2016 Valor Latino e Cedar Project Center Springs of Road Dallas Dallas, , Inc. TX 75235-6 805 ------------------------------------------------------------------------ Monetary Sero PO Box $15,000 2/29/2016 HIV is Not a Projec 1233 Crime t Inc. Milford regional , PA and 18337 national conferences and webinar trainings ------------------------------------------------------------------------ Monetary Shanti 730 Polk $10,000 7/13/2016 Shanti HIV Projec Street, Services t Inc. 3rd Program/HCV Floor Services San Francis co, CA 94109 ------------------------------------------------------------------------ Monetary South 601 $7,500 6/27/2016 West Centra Bland Virginia l Street Infection Educat P.O. Disease ional Box Coalition Develo 4322 pment Bluefie ld, WV 24701 ------------------------------------------------------------------------ Monetary Southwe 1101 N. $5,000 12/14/2016 General st Central mission Center Avenue support For Suite HIV/ 200 AIDS Phoenix Inc. , AZ 85004 ------------------------------------------------------------------------ Monetary Step-Up 850 N. $5,000 12/16/2016 Indianapolis Incorp Meridia Men orated n Advancing Street Prevention First (IMAP) Floor Indiana polis, IN 46204 ------------------------------------------------------------------------ Monetary The 17 Davis $65,000 12/6/2016 Ensuring Aids Blvd. Adequate Instit Suite Funding for ute 403 Domestic Tampa, HIV/AIDS FL and 33606 Hepatitis Programs ------------------------------------------------------------------------ Monetary The 429 E. $75 2/8/2016 Employee Health Vermont directed Founda Street, donation in tion Suite lieu of of 400 company Greate Indiana holiday r polis, gift Indian IN apolis 46202 ------------------------------------------------------------------------ Monetary The Hep 1325 S. $15,000 7/12/2016 HCV Patient C Colorad Linkage to Connec o Care and tion Blvd., Navigation B-302 Denver, CO 80222 ------------------------------------------------------------------------ Monetary The PO Box $30,000 8/24/2016 (RFA)--``Rep Open 99243 '' Door, Pittsbu presenting Inc. rgh, PA the 15233 solution for optimal health outcomes and housing stability for African American ``payees'' living with HIV/AIDS ------------------------------------------------------------------------ Monetary The San 3909 $5,000 3/7/2016 Latin@ Diego Centre Services LGBT St San program Commun Diego, ity CA Center 92103 ------------------------------------------------------------------------ Monetary The 85 $30,000 3/24/2016 Support Well Norman Information Projec Avenue, , t Suite 1 Community, P.O. Advocacy Box and 220410 Evaluation Brookly n, NY 11222 ------------------------------------------------------------------------ Monetary The 1331 $30,000 8/24/2016 (RFA)--Enhan Women' Rhode cements of s Island Community Collec Avenue Health tive NE Worker Washing Program ton, DC 20018 ------------------------------------------------------------------------ Monetary Tourett 4240 $75 5/4/2016 Donation in e Bell lieu of Associ Blvd., company ation Suite holiday of 205 gift Americ Bayside a , NY 11361 ------------------------------------------------------------------------ Monetary TPA 5050 N. $5,000 6/1/2016 Healthy Networ Broadwa Aging with k y Suite HIV Incorp 300 orated Chicago Test , IL Positi 60640 ve Aware Networ k ------------------------------------------------------------------------ Monetary TPA 5050 N. $25,000 10/6/2016 Total Care Networ Broadwa Portal k y Suite Incorp 300 orated Chicago Test , IL Positi 60640 ve Aware Networ k ------------------------------------------------------------------------ Monetary Treatme 261 $25,000 5/19/2016 Case Studies nt Fifth Action Ave Group, Suite Inc. 2110 New York, NY 10016 ------------------------------------------------------------------------ Monetary Univers UCSF $7,500 6/20/2016 Mission- ity of Allianc Based Califo e Support of rnia Health UCSF San Project Alliance Franci 1855 Health sco Folsom Project Street, Services Ste. for People 670 Box Living With 0884 or at Risk San of HIV/AIDS Francis co, CA 94143 ------------------------------------------------------------------------ Monetary Univers 5801 S. $20,741 3/7/2016 4 Her by Her ity of Ellis Chicag Avenue o Chicago , IL 60637 ------------------------------------------------------------------------ Monetary US 1300 PA $500,000 8/5/2016 Bedaquiline Agency Avenue. Donation for , NW SA- Program in Intern 44 Rm support of ationa 475-J World l Washing Health Develo ton, DC Organizatio pment 20523 n's END TB Strategy for 2016- 2035 ------------------------------------------------------------------------ Monetary Venice 604 Rose $5,000 12/16/2016 Venice Family Ave. Family Clinic Venice, Clinic's CA Common 90291 Ground ------------------------------------------------------------------------ Monetary Vermont 187 $5,000 6/1/2016 Vermont HIV Commit Saint Transportat tee Paul ion Support For Street Aids Burling Resour ton, VT ces 05401 Educat ion and Servic es ------------------------------------------------------------------------ Monetary Washing 566 West $30,000 3/24/2016 Engaging ton 181st High Risk Height Street, Active s Floor 2 Injection CORNER New Drug Users Projec York, in t NY Hepatitis C 10033 Testing and Treatment in Northern Manhattan ------------------------------------------------------------------------ Monetary Women 417 $7,500 4/25/2016 SafetyPIN On Welshwo Mainta od ining Drive, Educat Suite ion 303 And Nashvil Nutrit le, TN ion 37211- 4248 ------------------------------------------------------------------------ Monetary Womens 4615 $2,500 3/23/2016 She's Still Challe Harrier Got It nge Way educational Inc. Belcamp initiative , MD 21017 ------------------------------------------------------------------------ Monetary WORLD 389 30th $15,000 12/14/2016 Community Women St Researchers Organi Oakland Engaging zed to , CA Women Respon 94609 (CREW) III d to Life- threat ening Diseas es ------------------------------------------------------------------------ ---------------------------------------------------------------------------------------------------------------- ---------------------------------------------------------------------------------------------------------------- Product Johnson & Johnson One Johnson & $ 3,700,026 3/31/2016 Patient Assistance Patient Assistance Johnson Plaza New Product Donation Foundation Brunswick, NJ 08933 ---------------------------------------------------------------------------------------------------------------- Product Johnson & Johnson One Johnson & $ 3,459,402 6/30/2016 Patient Assistance Patient Assistance Johnson Plaza New Product Donation Foundation Brunswick, NJ 08934 ---------------------------------------------------------------------------------------------------------------- Product Johnson & Johnson One Johnson & $ 2,280,117 9/30/2016 Patient Assistance Patient Assistance Johnson Plaza New Product Donation Foundation Brunswick, NJ 08935 ---------------------------------------------------------------------------------------------------------------- Product Johnson & Johnson One Johnson & $ 3,874,808 12/31/2016 Patient Assistance Patient Assistance Johnson Plaza New Product Donation Foundation Brunswick, NJ 08936 ---------------------------------------------------------------------------------------------------------------- Product Partnership for 1616 Fort Myer $ 6,123,407 10/3/2016 Product donation Supply Chain Drive, 12th Floor for humanitarian Management Arlington, VA 22209- assistance. 3100 ---------------------------------------------------------------------------------------------------------------- Product US Agency for 1300 PA Avenue., NW, $ 44,580,000 12/1/2016 Bedaquiline product International SA-44 Rm 475-J donation Development Washington, DC 20523 ---------------------------------------------------------------------------------------------------------------- Updated March 30, 2018 Janssen Biotech, Inc. Monetary and Product Contribution to U.S.-based Charitable Organizations Full Year 2017 (Payments made from January 1, 2017 to December 31, 2017) ------------------------------------------------------------------------ Project Donation Payee Payee Payment Amount Payment Title/ Type Address (USD) Date Description ------------------------------------------------------------------------ Monetary AAUW 7511 $1,000 12/14/2017 Annual Makefi Germant Girl's eld own Recognition Area Avenue Reception Branch Philade and PA lphia, Scholarship Inc. PA Awards 19119 American Association of University Women--Make field Branch ------------------------------------------------------------------------ Monetary Aid For 12271 $300 11/16/2017 Costs Friend Townsen associated s d Rd. with Philade Janssen lphia, Cares PA Volunteer 19154 Activity--S eptember 27, 2017 ------------------------------------------------------------------------ Monetary Aid For 12271 $300 11/16/2017 Costs Friend Townsen associated s d Rd. with Philade Janssen lphia, Cares PA Volunteer 19154 Activity--O ctober 6, 2017 ------------------------------------------------------------------------ Monetary America 250 $9,500 2/2/2017 General n William Operating Cancer s Support Societ Street y NW (HDQTS Atlanta ) , GA 30303 ------------------------------------------------------------------------ Monetary America Atlanta $300 10/25/2017 Costs n Hope associated Cancer Lodge with Societ 1552 Janssen y Inc. Shoup Cares Ct Volunteer Decatur Activity , GA 30033 ------------------------------------------------------------------------ Monetary America 1626 $1,000 4/21/2017 Relay For n Locust Life of the Cancer Street Wissahickon Societ Philade Valley y Inc, lphia, Philad PA elphia 19103 , PA ------------------------------------------------------------------------ Monetary Arthrit 1355 $200,000 5/24/2017 Walk To Cure is Peachtr Arthritis Founda ee and Jingle tion Street, Bell Run Suite 600 Atlanta , GA 30309 ------------------------------------------------------------------------ Monetary Arthrit 1355 $200,000 12/21/2017 Walk To Cure is Peachtr Arthritis Founda ee and Jingle tion Street, Bell Run Suite 600 Atlanta , GA 30309 ------------------------------------------------------------------------ Monetary Artz 1229 $7,500 11/30/2017 ``ARTZ in Philad Chestnu the elphia t Neighborhoo Street, d: A #188 Community- Philade Based lphia, Program'' PA 19107 ------------------------------------------------------------------------ Monetary Breathi 600 West $5,000 12/25/2017 Program and ng Avenue, Family Room P.O. Services--B Founda Box 287 reathing tion Jenkint Room own, PA Foundation 19046-2 729 ------------------------------------------------------------------------ Monetary Cancer 3 $5,000 3/30/2017 Oncology Suppor Crossro Support t ads Groups Commun Drive ity Bedmins Centra ter, NJ l New 07921 Jersey ------------------------------------------------------------------------ Monetary Cancer 1200 Old $5,000 5/19/2017 Voice of the Suppor Henders Patient: t on Distress Commun Columbu Screening ity s, OH and Support Centra 43220 for Cancer l Ohio Patients and Survivors ------------------------------------------------------------------------ Monetary Cancer 200 Kirk $2,000 7/31/2017 Paws 4 Life Suppor Road Dog Walk t Warmins Commun ter, PA ity of 18974 Philad elphia ------------------------------------------------------------------------ Monetary Cancer 200 Kirk $300 11/30/2017 Costs Suppor Road associated t Warmins with Commun ter, PA Janssen ity of 18974 Cares Philad Volunteer elphia Activity--S eptember 28 2017 ------------------------------------------------------------------------ Monetary Cancer 200 Kirk $300 11/30/2017 Costs Suppor Road associated t Warmins with Commun ter, PA Janssen ity of 18974 Cares Philad Volunteer elphia Activity--S eptember 28 2017 ------------------------------------------------------------------------ Monetary Center 1617 $5,000 9/4/2017 Project for for John F. Medically Child Kennedy Needy Advoca Bouleva Children tes rd Philade lphia, PA 19103 ------------------------------------------------------------------------ Monetary Central 2500 $300 11/30/2017 Costs Bucks Lower associated Family State with YMCA Road Janssen Doylest Cares own, PA Volunteer 18901 Activity--O ctober 3 2017 ------------------------------------------------------------------------ Monetary Chester 100 $5,000 12/1/2017 Outreach County North Programs Art Bradfor Associ d ation Avenue West Chester , PA 19382 ------------------------------------------------------------------------ Monetary Chester 790 East $6,000 12/22/2017 Certified County Market Nurse Opport Street, Assistant unitie Suite (CNA) s 100 Program Indust West rializ Chester ation , PA Center 19382 ------------------------------------------------------------------------ Monetary Chestnu 1710 $2,500 11/30/2017 General t Hill Bethleh Operating Meals em Pike Support on Flourto Wheels wn, PA 19031 ------------------------------------------------------------------------ Monetary Childre 100 Penn $12,000 6/28/2017 Family Care n's Square Binder Hospit East Program al of 8th Philad Floor, elphia Suite Founda 8050 tion Philade lphia, PA 19107 ------------------------------------------------------------------------ Monetary Childre 100 Penn $6,000 4/13/2017 Walk for n's Square Hope Hospit East Benefiting al of 8th Pediatric Philad Floor, Inflammator elphia Suite y Bowel Founda 8050 Disease tion Philade Research at lphia, CHOP PA 19107 ------------------------------------------------------------------------ Monetary Communi 300B $25,000 12/21/2017 Provision of ty Lawrenc free Volunt e Drive medical and eers West dental in Chester healthcare Medici , PA to the ne 19380 uninsured in Chester County ------------------------------------------------------------------------ Monetary Crohn's 733 3rd $18,000 6/13/2017 Camp Oasis and Avenue Coliti Suite s 510 New Founda York, tion-- NY NY 10017 Chapte r ------------------------------------------------------------------------ Monetary Crohn's 733 3rd $100,000 10/30/2017 Take Steps and Avenue for Crohn's Coliti Suite and Colitis s 510 New Walks Founda York, tion-- NY NY 10017 Chapte r ------------------------------------------------------------------------ Monetary Delawar 236 $5,000 5/22/2017 Teacher e Randell Development Valley Hall Program Scienc 3141 e Chestnu Fairs, t Inc. Street Philade lphia, PA 19104 ------------------------------------------------------------------------ Monetary Emmanue 67 $3,500 12/21/2017 Pediatric l Walnut Cancer Cancer Ave. Family Founda Suite Financial tion 107 Assistance Clark, Fund NJ 07040 ------------------------------------------------------------------------ Monetary Family 142 $250,000 12/15/2017 Family Reach Reach Berkele Financial Founda y Assistance tion Street; and 4th Resource Floor Navigation Boston, Programs MA 02116 ------------------------------------------------------------------------ Monetary For 620 West $1,000 5/15/2017 7th Annual Pete's Germant For Pete's Sake own Sake, Walk! Cancer Pike at Citizens Respit Suite Bank Park e 250 Founda Plymout tion h Meeting , PA 19462 ------------------------------------------------------------------------ Monetary Friends 113 West $5,000 12/14/2017 Outreach to Associ Chestnu Homeless ation t Families For Street Care West and Chester Protec , PA tion 19380 Of Childr en ------------------------------------------------------------------------ Monetary Georgia 560 $2,500 5/11/2017 Free Prosta Barnesl Prostate te ey Lane Cancer Cancer Alphare Screening Coalit tta, GA ion 30022 Inc. ------------------------------------------------------------------------ Monetary Girl 330 $4,000 11/21/2017 Science, Scouts Manor Technology, of Road Engineering Southe Miquon, , and Math astern PA Outreach Pennsy 19444-1 Programming lvania 741 ------------------------------------------------------------------------ Monetary Global 515 N. $25,000 12/21/2017 Puerto Rico Health Midland Rheumatolog y Ave y Relief Living Upper Founda Nyack, tion, NY Inc. 10960 ------------------------------------------------------------------------ Monetary Habitat 1847 E $2,500 12/18/2017 Cambria for Lincoln Housing Humani Hwy Development ty of Coatesv -providing Cheste ille, decent r PA affordable County 19320 housing , Inc. options in Chester County Pa. ------------------------------------------------------------------------ Monetary Habitat 1829 N. $5,000 12/13/2017 Diamond Park For 19th Humani Street ty Philade Philad lphia, elphia PA Inc. 19121 ------------------------------------------------------------------------ Monetary Hatboro- 229 $25,000 12/1/2017 STEM Horsha Meeting Programs m house for Hatboro- Educat Road Horsham ional Horsham Students Founda , PA tion 19044 ------------------------------------------------------------------------ Monetary Jack 3282 $25,000 5/31/2017 WOW! And Northsi Experience Jill de Late Parkway Stage , NW Cancer Suite Founda 100 tion Atlanta Inc. , GA 33327 ------------------------------------------------------------------------ Monetary Joy of 580 $525 4/11/2017 Employee Sox Lindsey directed Dr., donation in Ste 150 lieu of Radnor, company PA holiday 19087 gift ------------------------------------------------------------------------ Monetary Kids 26071 $3,000 11/21/2017 Support Connec Merit Groups for ted Circle, the #103 Children of Laguna Cancer Hills, Patients CA 92653-7 016 ------------------------------------------------------------------------ Monetary Lenape 500 N. $ 300 11/30/2017 Costs Valley West associated Founda Street with tion Doylest Janssen own, PA Cares 18901 Volunteer Activity--S eptember 29 2017 ------------------------------------------------------------------------ Monetary Metropo 420 N $30,000 12/1/2017 Medical litan 20th Nutrition Area Street for People Neighb Philade with Severe orhood lphia, Illnesses Nutrit PA ion 19103 Allian ce (MANNA ) ------------------------------------------------------------------------ Monetary Mitzvah 1561 $5,000 11/28/2017 Critical Circle Gehman Needs for Founda Rd. Families tion Harleys and ville, Individuals PA 19438 ------------------------------------------------------------------------ Monetary Montgom 340 $33,660 10/27/2017 Bridge to ery Dekalb Employment County Pike Extension-- Commun Blue Wissahickon ity Bell, High School Colleg PA e 19422 Founda tion ------------------------------------------------------------------------ Monetary NAMI of 100 W, $2,500 10/4/2017 Mental PA Main health Montgo St. education, mery Suite support and County 204 advocacy Lansdal programs as e, PA well as 19446 support of Ending the Silence program ------------------------------------------------------------------------ Monetary NAMI of 100 W, $1,000 12/25/2017 NAMIWalks PA Main Greater Montgo St. Philadelphi mery Suite a County 204 Lansdal e, PA 19446 ------------------------------------------------------------------------ Monetary Nationa 1107 $2,500 5/31/2017 National l Lakevie Cancer Cancer w Dr, Survivors Surviv Suite Day 2017 ors C1 Day Frankli Founda n, TN tion 37067 ------------------------------------------------------------------------ Monetary Nationa 4950 $2,500 7/31/2017 19th Annual l York Break the Ovaria Rd, Silence on n Unit Ovarian Cancer 631 Cancer Run/ Coalit Holicon Walk ion g, PA Inc. 18928 ------------------------------------------------------------------------ Monetary Nationa 6600 SW $50,000 3/16/2017 2017 Team l 92nd NPF Walk Psoria Ave., sis #300 Founda Portlan tion d, OR 97223 ------------------------------------------------------------------------ Monetary Nationa 6600 SW $20,000 12/5/2017 Patient l 92nd 2017 Education Psoria Ave., Initiative: sis #300 Phase Three Founda Portlan tion d, OR 97223 ------------------------------------------------------------------------ Monetary North P.O. Box $5,000 12/4/2017 Project Penn 103 16 Learn Valley Susqueh Homework Boys anna Program and Avenue Girls Lansdal Club e, PA Inc. 19446 ------------------------------------------------------------------------ Monetary One P.O. Box $75 4/11/2017 Employee Days 18071 directed Wages Seattle donation in , WA lieu of 98118 company holiday gift ------------------------------------------------------------------------ Monetary Patient 700 12TH $5,000 3/31/2017 Patients s ST NW Rising Rising Ste. University: Inc. 700 Spotlight Washing Rheumatoid ton, DC Arthritis 20005 ------------------------------------------------------------------------ Monetary Philade 325 $5,000 1/24/2017 Summer READS lphia Chestnu Reads t Street- -Suite 903 Philade lphia, PA 19106 ------------------------------------------------------------------------ Monetary Project 1515 $2,000 11/30/2017 Ending Home Fairmou Homelessnes nt s in Avenue Philadelphi Philade a Through lphia, Supportive PA Housing 19130 ------------------------------------------------------------------------ Monetary Prostat 7009 S. $30,000 6/2/2017 Prostate e Potomac Cancer Cancer Street Disparities Educat Suite Outreach ion 125 Program Counci Centenn l ial, CO 80112 ------------------------------------------------------------------------ Monetary Quest 461 Cann $4,000 5/25/2017 Hippotherapy Therap Rd. (Equine- eutic West PAssisted Servic Chester Therapy) es , PA Program Inc. 19382 Support to Serve Children with Special Needs ------------------------------------------------------------------------ Monetary Rebuild 4355 $5,000 3/22/2017 Belmont ing Orchard Block Build Togeth Street 2017 er Suite Philad 2R elphia Philade lphia, PA 19124 ------------------------------------------------------------------------ Monetary Retired 901 East $7,000 5/31/2017 RSVP's and 8th America Senior Street Reads/ Volunt Suite Writes and eer 200 Protege Progra King of Programs m of Prussia Montgo , PA mery 19406 County ------------------------------------------------------------------------ Monetary Retired 901 East $10,000 12/13/2017 RSVP's My and 8th Free Tutor Senior Street (MFT) Volunt Suite Program and eer 200 Family Progra King of Literacy m of Prussia Volunteer Montgo , PA Program mery 19406 (FLVP) County ------------------------------------------------------------------------ Monetary Riverbe 1950 $6,000 7/31/2017 Philadelphia nd Spring Children Enviro Mill Access nmenta Road Nature l Gladwyn Program Educat e, PA ion 19035 Center ------------------------------------------------------------------------ Monetary Sandy 2010 $2,000 11/21/2017 Sandy Sprint Rollma West Superhero n Chester 5K or 10K Ovaria Pike, Run/Walk n Suite and Canine Cancer 410 Sprint Founda Haverto tion, wn, PA Inc. 19083 ------------------------------------------------------------------------ Monetary Sarcoma 9899 $2,500 11/16/2017 Race to Cure Founda Main SarcomaT 5K tion Street, Walk/Run of #204 Series Americ Damascu a s, MD 20872 ------------------------------------------------------------------------ Monetary Special 2800 $4,000 11/21/2017 Special Equest Street Equestrians rians Road Equine- P.O. Assisted Box Learning 1001 and Warring Therapeutic ton, PA Riding 18976 Program ------------------------------------------------------------------------ Monetary Starfin 4015 $10,000 5/24/2017 Starfinder's der Main Senior Founda Street Leaders tion Philade Program lphia, PA 19127 ------------------------------------------------------------------------ Monetary The 222 $10,000 12/22/2017 Corporate Frankl North Membership in 20th Instit Street ute Philade lphia, PA 19103 ------------------------------------------------------------------------ Monetary The PO Box $2,000 7/31/2017 General Giving 823 Operating Tree, Gwynedd Support Gwyned Valley, d PA Valley 19437 , PA ------------------------------------------------------------------------ Monetary The 3 $250,000 4/12/2017 FY 2018 Leukem Interna Light the ia and tional Night Lympho Drive National ma Suite Sponsor Societ 200 Rye y Brook, NY 10573 ------------------------------------------------------------------------ Monetary The 123 $7,500 12/14/2017 Master Class Mann South Artist Center Broad Residency for Street the Suite Perfor 815 ming Philade Arts lphia, PA 19109 ------------------------------------------------------------------------ Monetary The 2600 $10,000 4/25/2017 Hubert J.P. Melmar Wayland Schoemaker k Road Classic Charit Berwyn, able PA Founda 19312 tion Berwyn , PA ------------------------------------------------------------------------ Monetary Travis 164 E $5,000 12/13/2017 Character Manion State Does Matter Founda Street tion Doylest own, PA 18901 ------------------------------------------------------------------------ Monetary Trustee 3025 $6,000 12/14/2017 WXPN s of Walnut Musicians the Street On Call Univer Philade sity lphia, of PA Pennsy 19104 lvania ------------------------------------------------------------------------ Monetary Turning 415 $5,000 4/20/2017 Families and Points South Schools For 15th Together Childr Street (FAST) en Philade lphia, PA 19146 ------------------------------------------------------------------------ Monetary United 8085 $2,017 8/8/2017 General Mitoch Saltsbu mission ondria rg Road support l Suite Diseas 201 e Pittsbu Founda rgh, PA tion 15239 ------------------------------------------------------------------------ Monetary Us Too 2720 $1,000 5/25/2017 13th Annual Intern South SEA Blue ationa River Prostate l Inc. Road Cancer Walk #112 & Run Des Plaines , IL 60018 ------------------------------------------------------------------------ Monetary ZERO--T 515 King $1,250 8/1/2017 ZERO he End Street, Prostate of Ste 420 Cancer Run/ Prosta Alexand Walk te ria, VA Austin, TX Cancer 22314 ------------------------------------------------------------------------ Monetary ZERO--T 515 King $1,250 8/1/2017 ZERO he End Street, Prostate of Ste 420 Cancer Run/ Prosta Alexand Walk te ria, VA Columbus, Cancer 22314 OH ------------------------------------------------------------------------ Monetary ZERO--T 515 King $1,250 8/1/2017 ZERO he End Street, Prostate of Ste 420 Cancer Run/ Prosta Alexand Walk te ria, VA Charleston, Cancer 22314 SC ------------------------------------------------------------------------ Monetary ZERO--T 515 King $1,250 8/1/2017 ZERO he End Street, Prostate of Ste 420 Cancer Run/ Prosta Alexand Walk te ria, VA Boston, MA Cancer 22314 ------------------------------------------------------------------------ Monetary ZERO--T 515 King $1,250 8/1/2017 ZERO he End Street, Prostate of Ste 420 Cancer Run/ Prosta Alexand Walk te ria, VA Cleveland, Cancer 22314 OH ------------------------------------------------------------------------ Monetary ZERO--T 515 King $1,250 8/1/2017 ZERO he End Street, Prostate of Ste 420 Cancer Run/ Prosta Alexand Walk te ria, VA Birmingham, Cancer 22314 AL ------------------------------------------------------------------------ Monetary ZERO--T 515 King $1,250 8/1/2017 ZERO he End Street, Prostate of Ste 420 Cancer Run/ Prosta Alexand Walk San te ria, VA Diego, CA Cancer 22314 ------------------------------------------------------------------------ Monetary ZERO--T 515 King $1,250 8/1/2017 ZERO he End Street, Prostate of Ste 420 Cancer Run/ Prosta Alexand Walk San te ria, VA Antonio, TX Cancer 22314 ------------------------------------------------------------------------ Monetary ZERO--T 515 King $1,250 8/1/2017 ZERO he End Street, Prostate of Ste 420 Cancer Run/ Prosta Alexand Walk te ria, VA Sacramento, Cancer 22314 CA ------------------------------------------------------------------------ Monetary ZERO--T 515 King $1,250 8/1/2017 ZERO he End Street, Prostate of Ste 420 Cancer Run/ Prosta Alexand Walk te ria, VA Oklahoma Cancer 22314 City, OK ------------------------------------------------------------------------ Monetary ZERO--T 515 King $1,250 8/1/2017 ZERO he End Street, Prostate of Ste 420 Cancer Run/ Prosta Alexand Walk East te ria, VA Lansing, MI Cancer 22314 ------------------------------------------------------------------------ Monetary ZERO--T 515 King $1,250 8/1/2017 ZERO he End Street, Prostate of Ste 420 Cancer Run/ Prosta Alexand Walk Kansas te ria, VA City, KS Cancer 22314 ------------------------------------------------------------------------ Monetary ZERO--T 515 King $1,250 8/1/2017 ZERO he End Street, Prostate of Ste 420 Cancer Run/ Prosta Alexand Walk te ria, VA Jacksonvill Cancer 22314 e, FL ------------------------------------------------------------------------ Monetary ZERO--T 515 King $1,250 8/1/2017 ZERO he End Street, Prostate of Ste 420 Cancer Run/ Prosta Alexand Walk te ria, VA Harrisburg, Cancer 22314 PA ------------------------------------------------------------------------ Monetary ZERO--T 515 King $1,250 8/1/2017 ZERO he End Street, Prostate of Ste 420 Cancer Run/ Prosta Alexand Walk te ria, VA Greensboro, Cancer 22314 NC ------------------------------------------------------------------------ Monetary ZERO--T 515 King $1,250 8/1/2017 ZERO he End Street, Prostate of Ste 420 Cancer Run/ Prosta Alexand Walk Des te ria, VA Moines, IA Cancer 22314 ------------------------------------------------------------------------ Monetary ZERO--T 515 King $1,250 8/1/2017 ZERO he End Street, Prostate of Ste 420 Cancer Run/ Prosta Alexand Walk te ria, VA Dayton, OH Cancer 22314 ------------------------------------------------------------------------ Monetary ZERO--T 515 King $1,250 8/1/2017 ZERO he End Street, Prostate of Ste 420 Cancer Run/ Prosta Alexand Walk Dallas/ te ria, VA Fort Worth, Cancer 22314 TX ------------------------------------------------------------------------ Monetary ZERO--T 515 King $1,250 8/1/2017 ZERO he End Street, Prostate of Ste 420 Cancer Run/ Prosta Alexand Walk Corpus te ria, VA Christi, TX Cancer 22314 ------------------------------------------------------------------------ Monetary ZERO--T 515 King $1,250 8/1/2017 ZERO he End Street, Prostate of Ste 420 Cancer Run/ Prosta Alexand Walk te ria, VA Virginia Cancer 22314 Beach, VA ------------------------------------------------------------------------ Monetary ZERO--T 515 King $1,250 8/1/2017 ZERO he End Street, Prostate of Ste 420 Cancer Run/ Prosta Alexand Walk Tyler, te ria, VA TX Cancer 22314 ------------------------------------------------------------------------ Monetary ZERO--T 515 King $1,250 8/1/2017 ZERO he End Street, Prostate of Ste 420 Cancer Run/ Prosta Alexand Walk St. te ria, VA Louis, MO Cancer 22314 ------------------------------------------------------------------------ Monetary ZERO--T 515 King $1,250 8/1/2017 ZERO he End Street, Prostate of Ste 420 Cancer Run/ Prosta Alexand Walk Puget te ria, VA Sound, WA Cancer 22314 ------------------------------------------------------------------------ Monetary ZERO--T 515 King $1,250 8/1/2017 ZERO he End Street, Prostate of Ste 420 Cancer Run/ Prosta Alexand Walk San te ria, VA Francisco, Cancer 22314 CA ------------------------------------------------------------------------ Monetary ZERO--T 515 King $1,000 8/1/2017 ZERO he End Street, Prostate of Ste 420 Cancer Run/ Prosta Alexand Walk Napa te ria, VA Valley, CA Cancer 22314 ------------------------------------------------------------------------ Monetary ZERO--T 515 King $1,250 8/1/2017 ZERO he End Street, Prostate of Ste 420 Cancer Run/ Prosta Alexand Walk te ria, VA Minneapolis Cancer 22314 , MN ------------------------------------------------------------------------ Monetary ZERO--T 515 King $1,250 8/1/2017 ZERO he End Street, Prostate of Ste 420 Cancer Run/ Prosta Alexand Walk te ria, VA Hollywood, Cancer 22314 FL ------------------------------------------------------------------------ Monetary ZERO--T 515 King $1,250 8/1/2017 ZERO he End Street, Prostate of Ste 420 Cancer Run/ Prosta Alexand Walk te ria, VA Asheville, Cancer 22314 NC ------------------------------------------------------------------------ Monetary ZERO--T 515 King $1,250 8/1/2017 ZERO he End Street, Prostate of Ste 420 Cancer Run/ Prosta Alexand Walk te ria, VA Augusta, SC Cancer 22314 ------------------------------------------------------------------------ Monetary ZERO--T 515 King $1,250 8/1/2017 ZERO he End Street, Prostate of Ste 420 Cancer Run/ Prosta Alexand Walk Towson/ te ria, VA Baltimore, Cancer 22314 MD ------------------------------------------------------------------------ Monetary ZERO--T 515 King $1,250 8/1/2017 ZERO he End Street, Prostate of Ste 420 Cancer Run/ Prosta Alexand Walk El te ria, VA Paso, TX Cancer 22314 ------------------------------------------------------------------------ Monetary ZERO--T 515 King $1,250 8/1/2017 ZERO he End Street, Prostate of Ste 420 Cancer Run/ Prosta Alexand Walk te ria, VA Hartford, Cancer 22314 CT ------------------------------------------------------------------------ Monetary ZERO--T 515 King $1,250 8/1/2017 ZERO he End Street, Prostate of Ste 420 Cancer Run/ Prosta Alexand Walk te ria, VA Wichita, KS Cancer 22314 ------------------------------------------------------------------------ Monetary ZERO--T 515 King $1,250 8/1/2017 ZERO he End Street, Prostate of Ste 420 Cancer Run/ Prosta Alexand Walk te ria, VA Capital Cancer 22314 Area/ Arlington, VA ------------------------------------------------------------------------ Monetary ZERO--T 515 King $1,250 8/1/2017 ZERO he End Street, Prostate of Ste 420 Cancer Run/ Prosta Alexand Walk te ria, VA Syracuse, Cancer 22314 NY ------------------------------------------------------------------------ Monetary ZERO--T 515 King $1,250 8/1/2017 ZERO he End Street, Prostate of Ste 420 Cancer Run/ Prosta Alexand Walk Salt te ria, VA Lake City, Cancer 22314 UT ------------------------------------------------------------------------ Monetary ZERO--T 515 King $1,250 8/1/2017 ZERO he End Street, Prostate of Ste 420 Cancer Run/ Prosta Alexand Walk te ria, VA Raleigh, NC Cancer 22314 ------------------------------------------------------------------------ Monetary ZERO--T 515 King $1,250 8/1/2017 ZERO he End Street, Prostate of Ste 420 Cancer Run/ Prosta Alexand Walk te ria, VA Portland, Cancer 22314 OR ------------------------------------------------------------------------ Monetary ZERO--T 515 King $1,250 8/1/2017 ZERO he End Street, Prostate of Ste 420 Cancer Run/ Prosta Alexand Walk Los te ria, VA Angeles, CA Cancer 22314 ------------------------------------------------------------------------ Monetary ZERO--T 515 King $1,250 8/1/2017 ZERO he End Street, Prostate of Ste 420 Cancer Run/ Prosta Alexand Walk te ria, VA Lincoln, NE Cancer 22314 ------------------------------------------------------------------------ Monetary ZERO--T 515 King $1,250 8/1/2017 ZERO he End Street, Prostate of Ste 420 Cancer Run/ Prosta Alexand Walk Lehigh te ria, VA Valley, PA Cancer 22314 ------------------------------------------------------------------------ Monetary ZERO--T 515 King $20,000 6/16/2017 Printed News he End Street, Resource of Ste 420 for Men Prosta Alexand Living with te ria, VA Advanced Cancer 22314 Disease ------------------------------------------------------------------------ Product Johnson One $497,856,557 12/31/2017 Patient & Johnson Assistance Johnso & Product n Johnson Donation Patien Plaza t Kilmer Assist Square, ance Suite Founda 130 New tion Brunswi ck, NJ 08933 ------------------------------------------------------------------------ Janssen has also made financial donations to independent charitable foundations that assist patients who are underinsured and in financial need with treatment-related expenses. In keeping with our donor agreements and applicable regulatory guidance, we will only disclose aggregate data on our charitable giving and do not publicize information on donations to specific foundations and disease states. In 2017, we contributed approximately $61 million in donations to independent charitable foundations, enabling them to provide assistance with medication-related copays to patients with cancer and autoimmune diseases.Updated Updated March 30, 2018 Janssen Pharmaceuticals, Inc. Monetary and Product Contribution to U.S.- based Charitable Organizations Full Year 2017 (Payments made from January 1, 2017 to December 31, 2017) ------------------------------------------------------------------------ Project Donation Payee Payee Payment Amount Payment Title/ Type Address (USD) Date Description ------------------------------------------------------------------------ Monetary 180 1 $2,500 12/5/2017 2NDFLOOR Turnin Bethany Youth g Road, Helpline--H Lives Buildin unterdon, Around g 3 Mercer, , Inc. Suite Somerset 42 Operations Hazlet, NJ 07730 ------------------------------------------------------------------------ Monetary Adult 872 E. $300 11/6/2017 Costs Day Main associated Center Street with of Bridgew Janssen Somers ater, Cares et NJ Volunteer County 08807 Activity--O ctober 4, 2017 ------------------------------------------------------------------------ Monetary Allianc 2021 K $20,000 12/28/2017 ``Living e For Street with Atrial Aging N.W. Fibrillatio Resear Suite n'' Stroke ch 305 Prevention Washing PSA ton, DC Campaign 20006 ------------------------------------------------------------------------ Monetary Allies, 1262 $7,500 11/6/2017 Project Grow Inc. Whiteho rse Hamilto n Square Rd. Hamilto n, NJ 08690 ------------------------------------------------------------------------ Monetary Alterna 600 $300 9/29/2017 Costs tives First associated Ave. with Raritan Janssen , NJ Cares 08869 Volunteer Activity #2--Septemb er 12, 2017 ------------------------------------------------------------------------ Monetary Alterna 600 $300 9/29/2017 Costs tives First associated Ave. with Raritan Janssen , NJ Cares 08869 Volunteer Activity #1--Septemb er 12, 2017 ------------------------------------------------------------------------ Monetary Alterna 600 $7,500 12/13/2017 Fundraising tives First event Ave. support to Raritan benefit , NJ general 08869 mission of organizatio n ------------------------------------------------------------------------ Monetary America 900 Fort $10,000 5/2/2017 Stop n Street Diabetes @ Diabet Mall, Work es Suite Associ 940 ation Honolul u, HI 96813 ------------------------------------------------------------------------ Monetary America PO Box $30,000 12/22/2017 Atrial n 541 Fibrillatio Founda Greenwo n Patient tion od, TX Education For 76246 Conference, Women' AF Patient s Treatment Health and Stroke Prevention Decision- Making Tool, and AF Community Screening Pilot ------------------------------------------------------------------------ Monetary America 7272 $30,000 12/28/2017 Raising n Greenvi Awareness Heart lle Ave on the Dallas, Effects and TX Consequence 75231 s of Untreated Type 2 Diabetes ------------------------------------------------------------------------ Monetary America 7272 $30,000 12/28/2017 Increasing n Greenvi Awareness Heart lle Ave of Deep Dallas, Vein TX Thrombosis/ 75231 Venous Thromboembo lism in General Population and At-Risk Patients ------------------------------------------------------------------------ Monetary America One $300 9/29/2017 Costs n Union associated Heart Street with Associ Suite Janssen ation- 301 Cares -New Robbins Volunteer Jersey ville, Activity--O NJ ctober 7, 08691 2017 ------------------------------------------------------------------------ Monetary America One $5,000 12/4/2017 16th Annual n Union Garden Heart Street State Go Associ Suite Red For ation- 301 Women -New Robbins Luncheon Jersey ville, NJ 08691 ------------------------------------------------------------------------ Monetary America 1000 $200,000 12/12/2017 Judges and n Wilson Psychiatris Psychi Blvd, ts atric Suite Leadership Founda 1825 Initiative tion Arlingt (JPLI) on, VA 22209 ------------------------------------------------------------------------ Monetary America 1000 $100,000 12/12/2017 Typical or n Wilson Troubled? Psychi Blvd, School atric Suite Mental Founda 1825 Health tion Arlingt Education on, VA Program 22209 ------------------------------------------------------------------------ Monetary America 1000 $35,000 12/12/2017 Center for n Wilson Workplace Psychi Blvd, Mental atric Suite Health Founda 1825 (formerly tion Arlingt the on, VA Partnership 22209 for Workplace Mental Health) ------------------------------------------------------------------------ Monetary America 88 $600 11/28/2017 Donation In res Hamilto Lieu of Founda n Ave. Gift tion Stamfor d, CT 06902 ------------------------------------------------------------------------ Monetary America 150 $300 9/29/2017 Costs 's Pittsto associated Grow-A- wn Road with Row, Pittsto Janssen Inc. wn, NJ Cares 08867 Volunteer Activity--S eptember 27, 2017 ------------------------------------------------------------------------ Monetary America 150 $300 9/29/2017 Costs 's Pittsto associated Grow-A- wn Road with Row, Pittsto Janssen Inc. wn, NJ Cares 08867 Volunteer Activity--O ctober 6, 2017 ------------------------------------------------------------------------ Monetary Anchor 482 $300 9/29/2017 Costs House, Centre associated Inc. Street with Trenton Janssen , NJ Cares 08611 Volunteer Activity--S eptember 28, 2017 ------------------------------------------------------------------------ Monetary Anchor 482 $8,000 12/12/2017 Anchor House House, Centre Shelter Inc. Street Trenton , NJ 08611 ------------------------------------------------------------------------ Monetary Ann 595 W. $9,500 12/12/2017 Increasing Silver State Access to man Street Comprehensi Commun Doylest ve ity own, PA Healthcare Health 18901 for Low- Clinic Income, Uninsured Bucks County residents ------------------------------------------------------------------------ Monetary Arm In 123 E. $15,000 10/30/2017 Improving Arm, Hanover Food Inc. St. Security Trenton and Housing , NJ Stability 08608 ------------------------------------------------------------------------ Monetary Bear 1162 $750 12/12/2017 2018 Bear Tavern Bear Tavern Parent Tavern Elementary s Road Science Associ Titusvi Fair ation lle, NJ 08560 ------------------------------------------------------------------------ Monetary Big 2875 $6,500 10/30/2017 STEM School Brothe York Mentoring rs Big Road Initiative Sister Jamison s of , PA Bucks 18929 County ------------------------------------------------------------------------ Monetary Big 535 East $10,000 8/23/2017 Fundraising Brothe Frankli event rs Big n support to Sister Street benefit s of Trenton general Mercer , NJ mission of County 08610 organizatio n ------------------------------------------------------------------------ Monetary Big 535 East $7,500 10/16/2017 Youth Brothe Frankli Mentoring rs Big n Programs Sister Street s of Trenton Mercer , NJ County 08610 ------------------------------------------------------------------------ Monetary Boys 212 $20,000 10/30/2017 Extended Day and Centre Learning Girls Trenton Club , NJ of 08611 Trento n and Mercer County ------------------------------------------------------------------------ Monetary Bristol 120 $7,500 11/6/2017 ArtRageous Rivers Radclif Theatre ide fe Arts Theate Street Education r Co P.O. Program Inc. Box 1250 Bristol , PA 19007 ------------------------------------------------------------------------ Monetary Britesi 16 Sand $300 11/15/2017 Costs de Hill associated Adult Road with Day Fleming Janssen Center ton, NJ Cares s, 08822 Volunteer Inc. Activity--S eptember 22, 2017 ------------------------------------------------------------------------ Monetary Broward 305 SE $15,000 6/28/2017 Affordable County 18th Housing Commun Court ity Fort Develo Lauderd pment ale, FL Corpor 33316 ation, Inc. ------------------------------------------------------------------------ Monetary Bucks 400 $300 9/20/2017 Costs County Freedom associated Associ Drive with ation Newtown Janssen For , PA Cares The 18940 Volunteer Blind Activity--S And eptember Visual 26, 2017 ly Impair ed ------------------------------------------------------------------------ Monetary Bucks 626 $5,000 12/18/2017 Veterans County Jackson Housing Housin ville Assistance g Road Program Group Suite 140 Warmins ter, PA 18974 ------------------------------------------------------------------------ Monetary Bucks 100 $10,000 12/21/2017 Economic County Doyle Self- Opport Street Sufficiency unity Doylest Program Counci own, PA l, 18901 Inc. ------------------------------------------------------------------------ Monetary Caminar 2600 S. $7,500 8/11/2017 Bridges to El Wellness Camino Program Real, Suite 200 San Mateo, CA 94403 ------------------------------------------------------------------------ Monetary Capital PO Box $8,000 2/1/2017 ``I Am City 1743 Trenton!'': Commun Trenton Positive ity , NJ Images Founda 08607-1 Campaign tion 743 ------------------------------------------------------------------------ Monetary Catholi 920 $5,000 12/5/2017 CYO's Broad c South St. Trenton Youth Broad Center's Organi St. After zation Trenton School of , NJ Program Mercer 08611 Tutoring County Project ------------------------------------------------------------------------ Monetary Center 151 $10,000 10/13/2017 Community- for Lawrenc Based Altern e Health ative Street Services Senten 3rd for Justice- cing Floor Involved and Brookly Adults with Employ n, NY Schizophren ment 11201 ia Servic es (CASES ) ------------------------------------------------------------------------ Monetary Central 2500 $5,000 10/3/2017 Diabetes Bucks Lower Prevention Family State Program YMCA Road Doylest own, PA 18901 ------------------------------------------------------------------------ Monetary Child 204 N. $3,000 3/8/2017 Upper Bucks Home West Area Young and Street Parent Commun #101 Initiative ity Doylest own, PA 18901 ------------------------------------------------------------------------ Monetary Childre 635 $10,000 11/20/2017 CUNA and n's South Body and Home Clinton Soul Societ Avenue Prenatal y of Trenton Health New , NJ Education Jersey 08611 for Low- Income Women ------------------------------------------------------------------------ Monetary CIT 111 S. $5,000 8/15/2017 CIT Intern Highlan Internation ationa d St. al l, Box 71 Conference Inc. Memphis 2017 , TN 38111 ------------------------------------------------------------------------ Monetary Clevela 9500 $20,000 10/25/2017 Diabetes nd Euclid Center Clinic Ave., Educational Founda DV4 Initiatives tion Clevela at nd, OH Cleveland 44195 Clinic South Pointe Hospital ------------------------------------------------------------------------ Monetary College 50 Milk $20,000 12/28/2017 Campus Diabet St 16th Quality es Floor Improvement Networ Boston, : Diabetes k MA and Higher (CDN) 02109 Education ------------------------------------------------------------------------ Monetary College 2000 $20,000 11/20/2017 Nursing of New Penning Merit Jersey ton Scholarship Road s $7,500; P.O. and Box Educational 7718 Opportunity Ewing, Fund (EOF) NJ Promise 08628 Awards $12,500 ------------------------------------------------------------------------ Monetary Communi P.O. Box $5,000 12/5/2017 Rise Summer ty 88 116 Healthy Action North Food Servic Main Initiative e Street for Low- Center Hightst Income , Inc. own, NJ Youth 08520- 9804 ------------------------------------------------------------------------ Monetary Communi 4059 $5,000 3/8/2017 Arts for ty Skyron Seniors Conser Drive ($3,000) vatory Doylest and Music of own, PA Therapy Music 18902 ($2,000) ------------------------------------------------------------------------ Monetary Communi 4059 $4,500 11/6/2017 Making the ty Skyron Arts Conser Drive Accessible vatory Doylest for Seniors of own, PA and Persons Music 18902 with Disabilitie s: Music Therapy and Arts for Seniors ------------------------------------------------------------------------ Monetary Communi P.O. Box $60,000 12/18/2017 HealtheVoice ty 338 sTM Impact Founda Morrist Fund tion own, NJ of New 07963- Jersey 0338 ------------------------------------------------------------------------ Monetary Communi P.O. Box $75,000 12/18/2017 Healthcare ty 338 and Basic Founda Morrist Needs Fund tion own, NJ of New 07963- Jersey 0338 ------------------------------------------------------------------------ Monetary Communi P.O. Box $14,000 7/17/2017 ``Each One, ty 15176 Teach Health 407 One'': Coalit Crutchf Community ion, ield Empowerment Inc. Street Diabetes Durham, Self- NC Management 27704 Education Program ------------------------------------------------------------------------ Monetary Communi 959 $11,000 6/14/2017 Pathway to ty Route Recovery Hope, 46 East Residential Inc. Suite Programs/ 402 The Annual Parsipp Forum and any, NJ Wellness 07054 Fair ------------------------------------------------------------------------ Monetary Communi 959 $15,000 10/16/2017 Hope for ty Route Veterans Hope, 46 East and Valley Inc. Suite Brook 402 Village for Parsipp Veterans any, NJ 07054 ------------------------------------------------------------------------ Monetary Communi 310 W. $5,000 12/18/2017 Basic Needs: ty State Legal Justic Street, Services e 3rd Center Floor , Inc. Trenton , NJ 08618 ------------------------------------------------------------------------ Monetary Compeer 259 $2,500 5/31/2017 Caregiver Roches Monroe Support ter, Avenue Inc. Rochest er, NY 14607 ------------------------------------------------------------------------ Monetary Contact 60 S. $8,500 12/4/2017 Emotional Of Main Support and Mercer St. Crisis County Penning Services: New ton, NJ HOTLINE, Jersey 08628 Crisis Chat Inc. and TxtToday ------------------------------------------------------------------------ Monetary CONTACT P.O. Box $4,000 10/4/2017 Training We 2376 Nonprofessi Care, Westfie onals in Inc. ld, NJ Crisis 07091 Interventio n for People Experiencin g Psychosis ------------------------------------------------------------------------ Monetary Court 1450 $300 8/29/2017 Costs Appoin Parksid associated ted e with Specia Avenue, Janssen l Suite Cares Advoca 22 Volunteer tes Ewing, Activity--S NJ eptember 08638- 12, 2017 2946 ------------------------------------------------------------------------ Monetary Court 1450 $15,000 11/20/2017 General Appoin Parksid mission ted e support Specia Avenue, l Suite Advoca 22 tes Ewing, NJ 08638- 2946 ------------------------------------------------------------------------ Monetary Deborah 212 $5,000 12/22/2017 2018 Women's Hospit Trenton Heart al Road Health Founda Browns Educational tion Mills, Expo NJ 08015 ------------------------------------------------------------------------ Monetary Delawar 14 $4,500 11/6/2017 Environmenta e Michael l education River McCorri for Steamb stin underfunded oat Road and Floati Hamilto underserved ng n, NJ schools and Classr 08690 youth oom, groups Inc. ------------------------------------------------------------------------ Monetary Depress 5 $1,000 3/8/2017 DBSA NJ ion Village Mutual Aid and Ct. Support Bipola Lawrenc Group r eville, Facilitator Suppor NJ Training t 08648 Allian ce ------------------------------------------------------------------------ Monetary Diabete 14652 $5,000 3/23/2017 The Diabetes s Corkwoo UnConferenc Collec d Drive e tive, Tampa, Inc. FL 33626 ------------------------------------------------------------------------ Monetary Dress 3131 $10,000 10/16/2017 Women's for Princet Empowerment Succes on Pike Programs s Buildin g 4, Suite 209 Lawrenc eville, NJ 08648 ------------------------------------------------------------------------ Monetary Eden 2 $10,000 10/16/2017 Adult Autism Merwick Employment Servic Road Program es Princet Founda on, NJ tion 08540 ------------------------------------------------------------------------ Monetary Eden 2 $10,000 12/18/2017 Eden Dreams Autism Merwick Sponsorship Servic Road es Princet Founda on, NJ tion 08540 ------------------------------------------------------------------------ Monetary Emory 550 $3,500 7/3/2017 Atrial Univer Peachtr Fibrillatio sity ee n Support Street Group 6th Fl, Meeting Suite 4300 Atlanta , GA 30308 ------------------------------------------------------------------------ Monetary Enable, 13 $7,500 12/12/2017 Connect with Inc. Roszel Enable--Div Road, ersity Suite Drive B110 Princet on, NJ 08540 ------------------------------------------------------------------------ Monetary Every Fred $9,000 12/4/2017 Every Child Child Vereen, Valued Valued Jr. (ECV) After A NJ Communi School Nonpro ty Program fit Center Corpor 175 ation Johnson Avenue Lawrenc eville, NJ 08648 ------------------------------------------------------------------------ Monetary Everybo 707 $7,500 12/4/2017 Coming Up dy Alexand for AIRTM Loves er Kenny Road, Projec Suite t Inc. 208 Princet on, NJ 08540 ------------------------------------------------------------------------ Monetary Familie 320 N. $3,500 8/29/2017 DBT-Based s and Goodman Coping Friend St., Skills for s of Suite Families the 102 Mental Rochest ly Ill er, NY and 14607 Emotio nally Distur bed, Inc, dba NAMI- Roches ter ------------------------------------------------------------------------ Monetary Family 1931 $300 8/24/2017 Costs Guidan Notting associated ce ham Way with Center Hamilto Janssen Corpor n, NJ Cares ation 08619 Volunteer Activity--S eptember 28, 2017 ------------------------------------------------------------------------ Monetary Family 1931 $10,000 10/27/2017 Outpatient Guidan Notting mental ce ham Way health Center Hamilto treatment Corpor n, NJ for ation 08619 homeless women and children. ------------------------------------------------------------------------ Monetary Family 1 AAA Dr $12,500 11/20/2017 Caregiver Resour Suite Wellness ce 203 Series Networ Trenton k , NJ 08691 ------------------------------------------------------------------------ Monetary Family 4 $14,000 12/4/2017 Nurse Servic Corners Educator at e tone Bucks Associ Drive County ation Langhor Emergency of ne, PA Homeless Bucks 19047 Shelter County ------------------------------------------------------------------------ Monetary Federat One $2,500 5/31/2017 Big Nosh ion of Farming Vocational Organi dale Services zation Road Program s West Babylon , NY 11704 ------------------------------------------------------------------------ Monetary Feed Central $75 2/24/2017 Employee More, Virgini directed Inc. a Food donation in Bank lieu of 1415 company Rhoadmi holiday ller gift Street Richmon d, VA 23220 ------------------------------------------------------------------------ Monetary Florida 2525 $1,500 10/13/2017 2017 Florida Coalit Saint Institute ion Lucie on for Avenue Homelessnes the Vero s and Homele Beach, Supportive ss, FL Housing Inc. 32960 ------------------------------------------------------------------------ Monetary Forsyth 4881 $75 4/11/2017 Employee Humane Country directed Societ Club donation in y Rd. lieu of Winston company Salem, holiday NC gift 27104 ------------------------------------------------------------------------ Monetary Foundat 2381 $2,500 12/5/2017 Funding ion of Lawrenc support for Morris eville the 2018 Hall/ Road Philly Pops St. Lawrenc Benefit Lawren eville, Concert ce NJ 08648 ------------------------------------------------------------------------ Monetary Foundat 2381 $7,000 12/5/2017 It's Never 2 ion of Lawrenc Late Morris eville Hall/ Road St. Lawrenc Lawren eville, ce NJ 08648 ------------------------------------------------------------------------ Monetary Fountai 425 West $2,500 10/16/2017 Danny Zorn n 47th Scholarship House Street Fund New York, NY 10036 ------------------------------------------------------------------------ Monetary Fountai 425 West $6,000 10/16/2017 Mad About n 47th Art Auction House Street and Benefit New York, NY 10036 ------------------------------------------------------------------------ Monetary Fountai 425 West $1,000 3/23/2017 Fountain n 47th House One- House Street in-Four 5K New York, NY 10036 ------------------------------------------------------------------------ Monetary Friends P.O. Box $10,125 11/20/2017 Project Of 395 Hopewell Hopewe Penning Healthy ll ton, NJ Habitats Valley 08534 Open Space ------------------------------------------------------------------------ Monetary Friends P.O. Box $2,500 10/27/2017 Fundraising Of 395 event Hopewe Penning support to ll ton, NJ benefit Valley 08534 general Open mission of Space organizatio n ------------------------------------------------------------------------ Monetary Friends 6 Lilly $3,600 12/18/2017 Giving Voice of Street Through Lamber Lambert Film tville ville, Librar NJ y, 08530 Inc. ------------------------------------------------------------------------ Monetary Friends 57 $300 10/16/2017 Costs Of Mountai associated Prince n with ton Avenue Janssen Open Princet Cares Space on, NJ Volunteer 08540 Activity--S eptember 13, 2017 ------------------------------------------------------------------------ Monetary Gateway 4901 $10,000 8/29/2017 Outpatient Homes, Libbie Clinical Inc. Mill Services to East Support Bouleva Individuals rd with Suite Schizophren 210 ia and Richmon Schizoaffec d, VA tive 23230 Disorder ------------------------------------------------------------------------ Monetary Georgia 246 $2,000 8/21/2017 26th Annual Mental Sycamor Statewide Health e St. Consumer Consum Suite Conference er 260 Networ Decatur k , GA 30030 ------------------------------------------------------------------------ Monetary Globalg 1110 $825 11/30/2017 Donation In iving Vermont Lieu of Founda Ave. NW Gift tion, Suite Inc. 550 Washing ton, DC 20005 ------------------------------------------------------------------------ Monetary Good 38 Elm $5,000 12/18/2017 Nights of Grief, Street Support--Pr Inc. Morrist inceton own, NJ Center 07960 ------------------------------------------------------------------------ Monetary Greater 102 $150,000 2/2/2017 Greater Trento Barrack Trenton n Street Initiative Trenton , NJ 08608 ------------------------------------------------------------------------ Monetary Grounds 80 $7,500 12/4/2017 Wellness for Sculpto Walks Sculpt rs Way ure Hamilto n, NJ 08534 ------------------------------------------------------------------------ Monetary Habitat 530 $300 12/18/2017 Costs for Route associated Humani 38 E with ty of Maple Janssen Burlin Shade, Cares gton NJ Volunteer County 08052 Activity--O and ctober 6, Greate 2017 r Trento n- Prince ton ------------------------------------------------------------------------ Monetary Habitat 530 $300 12/18/2017 Costs for Route associated Humani 38 E with ty of Maple Janssen Burlin Shade, Cares gton NJ Volunteer County 08052 Activity--O and ctober 4, Greate 2017 r Trento n- Prince ton ------------------------------------------------------------------------ Monetary Habitat 530 $300 12/18/2017 Costs for Route associated Humani 38 E with ty of Maple Janssen Burlin Shade, Cares gton NJ Volunteer County 08052 Activity--S and eptember Greate 29, 2017 r Trento n- Prince ton ------------------------------------------------------------------------ Monetary Habitat 530 $300 12/18/2017 Costs for Route associated Humani 38 E with ty of Maple Janssen Burlin Shade, Cares gton NJ Volunteer County 08052 Activity--S and eptember 8, Greate 2017 r Trento n- Prince ton ------------------------------------------------------------------------ Monetary Habitat 530 $5,000 12/18/2017 Affordable for Route Homeownersh Humani 38 E ip Program ty of Maple Burlin Shade, gton NJ County 08052 and Greate r Trento n- Prince ton ------------------------------------------------------------------------ Monetary Habitat 31 Oak $7,500 11/6/2017 Women Build for Avenue, and Safe at Humani Suite Home Repair ty of 100 Clinics Greate Chalfon r t, PA Bucks 18914 ------------------------------------------------------------------------ Monetary Heart 1325 G $30,000 12/22/2017 HRS-WebMD: Rhythm Street Atrial Societ NW, Fibrillatio y, Suite n and How Inc. 400 to Reduce Washing Your Risk ton, DC of Stroke 20005 ------------------------------------------------------------------------ Monetary Heartla 4750 N. $7,500 8/11/2017 Pathways nd Sherida Home Health n Road Outrea Chicago ch , IL 60640 ------------------------------------------------------------------------ Monetary Henders 4740 $7,500 5/31/2017 Helping on North Individuals Behavi State Live Longer oral Road 7 (HILL) Health Lauderd ale Lakes, FL 33319 ------------------------------------------------------------------------ Monetary HiTOPS, 21 $9,000 12/12/2017 HiTOPS Inc. Wiggins Comprehensi Street ve Princet Sexuality on, NJ Interventio 08540 ns for Youth-at- Risk ------------------------------------------------------------------------ Monetary HomeFro 1880 $300 10/30/2017 Costs nt Princet associated on with Avenue Janssen Lawrenc Cares eville, Volunteer NJ Activity--O 08648 ctober 20, 2017 ------------------------------------------------------------------------ Monetary HomeFro 1880 $300 10/30/2017 Costs nt Princet associated on with Avenue Janssen Lawrenc Cares eville, Volunteer NJ Activity--S 08648 eptember 27, 2017 ------------------------------------------------------------------------ Monetary HomeFro 1880 $300 10/30/2017 Costs nt Princet associated on with Avenue Janssen Lawrenc Cares eville, Volunteer NJ Activity--S 08648 eptember 20, 2017 ------------------------------------------------------------------------ Monetary HomeFro 1880 $10,000 11/20/2017 Helping nt Princet Homeless on Families Avenue Break the Lawrenc Cycle of eville, Poverty NJ 08648 ------------------------------------------------------------------------ Monetary Hopewel 35 $750 12/12/2017 2018 l Princet Hopewell Elemen on Elementary tary Avenue School School Hopewel Science Parent l, NJ Fair Teache 08525 r Organi zation Inc. ------------------------------------------------------------------------ Monetary Hopewel PO Box $6,446 12/4/2017 Scholarship l 553 Support: Valley Penning $1,000; Educat ton, NJ STEM ion 08534 Education Founda and tion Sustainabil ity Education at Hopewell Elementary and Stony Brook Elementary Schools : $5446 ------------------------------------------------------------------------ Monetary Hopewel 48 $1,500 12/4/2017 Mobility for l Orchard Homebound Valley Ave PO Residents Senior Box 567 of the Founda Penning Hopewell tion ton, NJ Valley 08534 ------------------------------------------------------------------------ Monetary Hopewel P.O. Box $2,525 12/18/2017 Scholarship l 159 16 Fund Valley Seminar Youth y Choral Avenue, e, Suite C Inc. Hopewel l, NJ 08525 ------------------------------------------------------------------------ Monetary Hunterd 7 Lower $7,500 12/4/2017 Open Studio/ on Art Center Open Center Street Hearts: Clinton Artistic , NJ Expressions 08809 and Art with Heart ------------------------------------------------------------------------ Monetary Hunterd 1410 $2,500 11/6/2017 Fundraising on Route event County 22 West sponsorship YMCA Annanda to benefit le, NJ general 08801 mission of organizatio n ------------------------------------------------------------------------ Monetary Hunterd 111 Mine $300 9/29/2017 Costs on Street associated Land Fleming with Trust ton, NJ Janssen 08822 Cares Volunteer Activity--S eptember 14, 2017 ------------------------------------------------------------------------ Monetary Hunterd 111 Mine $2,500 12/4/2017 Promotion on Street and Land Fleming Protection Trust ton, NJ of 08822 Preserves ------------------------------------------------------------------------ Monetary Interfa 3635 $15,000 10/30/2017 Neighbors ith Quakerb Helping Caregi ridge Neighbors vers Road, Trento Suite n, #16 Inc. Hamilto n, NJ 08619 ------------------------------------------------------------------------ Monetary Isles, 10 Wood $300 9/29/2017 Costs Inc. Street associated Trenton with , NJ Janssen 08618 Cares Volunteer Activity--S eptember 20, 2017 ------------------------------------------------------------------------ Monetary Isles, 10 Wood $9,000 12/12/2017 Trenton Inc. Street Healthy Trenton Homes , NJ 08618 ------------------------------------------------------------------------ Monetary Jewish 707 $300 9/29/2017 Costs Family Alexand associated and er Road with Childr Suite Janssen en's 102 Cares Servic Princet Volunteer e of on, NJ Activity--S Greate 08540 eptember r 28, 2017 Mercer County ------------------------------------------------------------------------ Monetary Jewish 707 $15,000 12/18/2017 Senior Family Alexand Outreach and er Road Service Childr Suite (SOS) PLUS en's 102 ($12,000); Servic Princet Caregiver e of on, NJ Program Greate 08540 ($3,000) r Mercer County ------------------------------------------------------------------------ Monetary Jewish 150-A $5,000 10/30/2017 Expanding Family West Horizons Servic High e of St. Somers Somervi et lle, NJ Hunter 08876 don and Warren Counti es Inc. ------------------------------------------------------------------------ Monetary Johnson One $5,500,000 7/3/2017 General & Johnson mission Johnso & support n Johnson Patien Plaza t Kilmer Assist Square ance Suite Founda 130 New tion Brunswi Inc. ck, NJ 08933 ------------------------------------------------------------------------ Monetary Johnson One $15,500,000 9/28/2017 General & Johnson mission Johnso & support n Johnson Patien Plaza t Kilmer Assist Square ance Suite Founda 130 New tion Brunswi Inc. ck, NJ 08933 ------------------------------------------------------------------------ Monetary Johnson One $2,400,000 12/18/2017 General & Johnson mission Johnso & support n Johnson Patien Plaza t Kilmer Assist Square ance Suite Founda 130 New tion Brunswi Inc. ck, NJ 08933 ------------------------------------------------------------------------ Monetary Junior 360 Pear $7,150 10/30/2017 STEMCivics Achiev Blossom High School ement Drive Heroes JA of New Edison, Day Jersey NJ 08837 ------------------------------------------------------------------------ Monetary Kidsbri 999 $10,000 10/16/2017 Bullying dge, Lower Prevention Inc. Ferry and Rd Diversity Ewing, Appreciatio NJ n Life 08628 Skills Program for At-Risk Middle School Students in Trenton ------------------------------------------------------------------------ Monetary Kidsbri 999 $9,500 2/1/2017 Bullying dge, Lower Prevention Inc. Ferry and Rd Diversity Ewing, Appreciatio NJ n Life 08628 Skills Program for At-Risk Elementary/ Middle School Students in Trenton ------------------------------------------------------------------------ Monetary Latin 669 $5,000 12/12/2017 FUTURO Americ Chamber an s Legal Street, Defens Suite B e and Trenton Educat , NJ ional 08611 Fund Inc. ------------------------------------------------------------------------ Monetary Leyden 10001 W $25,000 12/12/2017 Transitional Family Grand Living Servic Ave Program e and Frankli Expansion Mental n Park, Health IL Center 60131 ------------------------------------------------------------------------ Monetary LifeTie 2205 $8,000 12/18/2017 Programs to s, Penning Serve Inc. ton Chronically Road Ill and Ewing, Abused and NJ Neglected 08638 Older Youth Transitioni ng Into Adulthood. ------------------------------------------------------------------------ Monetary Literac 100 $5,000 12/12/2017 Women y New Menlo Empowered Jersey Park (WE) , Inc. Drive, Suite 314 Edison, NJ 08837 ------------------------------------------------------------------------ Monetary Literac 120 $4,000 12/12/2017 Health y Findern Literacy Volunt e for All eers Avenue of Box 7 Somers Bridgew et ater, County NJ 08807 ------------------------------------------------------------------------ Monetary Main 8 $1,000 5/31/2017 Crisis Street Marcell Interventio Counse a n Team ling Avenue Training Center West for Essex Orange, County Law NJ Enforcement 07052 ------------------------------------------------------------------------ Monetary Main 8 $5,000 6/12/2017 Accessible Street Marcell Mental Counse a Health Care ling Avenue for Center West Individuals Orange, Suffering NJ From 07052 Schizoaffec tive Disorder ------------------------------------------------------------------------ Monetary Massach 15 $3,500 2/6/2017 Changing usetts Vernon Minds and Clubho Street Expanding use Waltham Employment Coalit , MA Campaign ion 02453 ------------------------------------------------------------------------ Monetary McCarte 91 $10,000 11/20/2017 OnStage r Univers Seniors: A Theatr ity Community e Place Project of Center Princet McCarter on, NJ Theatre 08540 ------------------------------------------------------------------------ Monetary Meals 320 $300 9/29/2017 Costs on Hollowb associated Wheels rook with of Drive Janssen Trento Ewing, Cares n NJ Volunteer Ewing 08638 Activity--O ctober 4, 2017 ------------------------------------------------------------------------ Monetary Meals 320 $15,000 11/6/2017 Subsidized on Hollowb Meal Wheels rook Program of Drive (SMP) Trento Ewing, n NJ Ewing 08638 ------------------------------------------------------------------------ Monetary Mental 500 $50,000 9/21/2017 General Health Montgom mission Americ ery St. support a Suite 820 Alexand ria, VA 22314 ------------------------------------------------------------------------ Monetary Mental 500 $100,000 12/12/2017 Social Self- Health Montgom Directed Americ ery St. Care (SSDC) a Suite 820 Alexand ria, VA 22314 ------------------------------------------------------------------------ Monetary Mental 2211 $7,500 10/20/2017 Mental Health Norfolk Health Americ , Suite Advocacy a of 810 Greate Houston r , TX Housto 77098 n ------------------------------------------------------------------------ Monetary Mental 2323 W $10,000 5/24/2017 Get Health 5th Connected Americ Ave. a of Suite Frankl 160 in Columbu County s, OH 43204 ------------------------------------------------------------------------ Monetary Mental 1210 San $2,500 4/24/2017 Mental Health Antonio Health Americ , Suite Education a of 200 and Texas Austin, Advocacy TX Campaign 78701 ------------------------------------------------------------------------ Monetary Mental 100 W. $2,000 10/13/2017 Community Health 10th Mental Associ St. Health ation Ste. Conference in 600 2017 Delawa Wilming re ton, DE 19801 ------------------------------------------------------------------------ Monetary Mental 100 W. $1,000 10/3/2017 E-Racing the Health 10th Blues for Associ St. Mental ation Ste. Health Run/ in 600 Walk Delawa Wilming re ton, DE 19801 ------------------------------------------------------------------------ Monetary Mental 617 $2,500 5/31/2017 Operating Health Garden Support for Associ Street the ation Santa Fellowship in Barbara Club Santa , CA Barbar 93101 a County ------------------------------------------------------------------------ Monetary Mental 3701 $7,500 5/31/2017 ParentVOICE Health Latrobe Associ Drive, ation Suite of 140 Centra Charlot l te, NC Caroli 28211 nas, Inc. ------------------------------------------------------------------------ Monetary Mental 580 $1,000 5/31/2017 Get On Your Health White Mat For Associ Plains Mental ation Road Health of Suite Westch 510 ester Tarryto wn, NY 10591 ------------------------------------------------------------------------ Monetary Mental 3809 $12,500 8/30/2017 Outreach and Illnes Rosewoo Behavioral s d Drive Healthcare Recove P.O. for ry Box Homeless Center 4246 Individuals , Inc. Columbi with Mental a, SC Illness 29240 ------------------------------------------------------------------------ Monetary Mercer 1001 $15,000 12/19/2017 Addressing Allian Spruce Young Adult ce to Street Homelessnes End Suite s, through Homele 205 planning, ssness Trenton assertive , NJ engagement, 08638 housing, and healthcare access ------------------------------------------------------------------------ Monetary Mercer P.O. Box $6,500 11/6/2017 Miscellaneou County 17202 s medical Commun Trenton equipment ity , NJ ($1,000), Colleg 08690 and work e study Founda student tion mentors ($3,500) to provide academic enrichment for health profession students success ------------------------------------------------------------------------ Monetary Mercer 3 Creek $1,000 11/20/2017 Mercer Scienc Rim Science e And Drive Fair 2018 Engine Titusvi ering lle, NJ Club 08560 ------------------------------------------------------------------------ Monetary Mercer 151 $300 8/24/2017 Costs Street Mercer associated Friend Street with s Trenton Janssen , NJ Cares 08611 Volunteer Activity--O ctober 4, 2017 ------------------------------------------------------------------------ Monetary Mercer 151 $300 8/24/2017 Costs Street Mercer associated Friend Street with s Trenton Janssen , NJ Cares 08611 Volunteer Activity--S eptember 14, 2017 ------------------------------------------------------------------------ Monetary Mercer 151 $25,000 10/30/2017 Mercer Street Mercer Street Friend Street Friends s Trenton Food Bank , NJ 08611 ------------------------------------------------------------------------ Monetary Middle P.O. Bos $15,000 10/16/2017 Outreach Earth 8045 Program and 520 Community North Youth Bridge Center Street Bridgew ater, NJ 08807 ------------------------------------------------------------------------ Monetary MIDJers 423 $5,000 8/16/2017 City of ey Rivervi Trenton--Su Center ew mmer Youth for Plaza Employment Econom Trenton Program ic , NJ Develo 08611 pment ------------------------------------------------------------------------ Monetary Midland 60 $6,500 8/16/2017 Midland Adult Industr Meals on Servic ial Wheels es, Parkway Employment Inc. P.O. Training Box Program 5026 North Branch, NJ 08876 ------------------------------------------------------------------------ Monetary Midland 94 $300 9/13/2017 Costs Founda Reading associated tion ton with Road Janssen P.O. Cares Box Volunteer 5026 Activity--O North ctober 3, Branch, 2017 NJ 08876 ------------------------------------------------------------------------ Monetary Millhil 101 $5,000 10/30/2017 Trenton Area l Oakland Stakeholder Child Street s and Trenton Family , NJ Develo 08618 pment ------------------------------------------------------------------------ Monetary Millhil 101 $15,000 10/30/2017 Millhill l Oakland Trenton Child Street PEERS and Trenton Family , NJ Develo 08618 pment ------------------------------------------------------------------------ Monetary Morven 55 $5,000 11/6/2017 Internships Museum Stockto for At-Risk and n Youth Garden Street Princet on, NJ 08540 ------------------------------------------------------------------------ Monetary Mount 73 North $15,000 10/27/2017 In Home Carmel Clinton Nursing Guild Avenue Services Trenton , NJ 08609 ------------------------------------------------------------------------ Monetary NAMI 7500 $3,000 10/4/2017 Educational Greenwo and od Ave Training N Programs Seattle , WA 98103 ------------------------------------------------------------------------ Monetary NAMI--C 1904 $2,500 8/14/2017 Education VA Byrd and support Centra Avenue programs l Suite and Virgin 207 HelpLine ias (POB Voice 18086) On Richmon Mental d, VA Illnes 23230 s ------------------------------------------------------------------------ Monetary NAMI 107 $5,000 8/29/2017 NAMI Ending Geauga South the Silence County Street; # 5 Chardon , OH 44024 ------------------------------------------------------------------------ Monetary NAMI 107 $2,000 8/29/2017 NAMI Geauga South Connection County Street; and Peer-to- # 5 Peer Chardon Collaborati , OH on A Peer- 44024 led Support and Education Program ------------------------------------------------------------------------ Monetary NAMI 4161 NW $1,000 5/31/2017 NAMIWalks Browar 5 St. Broward d Suite County County 203 , Inc. Plantat ion, FL 33317 ------------------------------------------------------------------------ Monetary NAMI 8324 $1,000 3/20/2017 NAMI CCNS 5k Cook Skokie Run/Walk County Blvd 2017 North Skokie, Suburb IL an 60077 ------------------------------------------------------------------------ Monetary NAMI 2400 W. $1,000 3/20/2017 2017 Delawa 4th NAMIWalks re Street Delaware Wilming ton, DE 19805 ------------------------------------------------------------------------ Monetary NAMI P.O. Box $2,500 10/4/2017 Support Hernan 5613 Services do Spring and CARE Hill, Line FL 34609 ------------------------------------------------------------------------ Monetary NAMI 1235 $10,000 10/16/2017 Education Mercer Whiteho and Support NJ rse Programs Mercerv for Mental ille Health Road Consumers Bldg. and Family C, Members Suite 303 Hamilto n, NJ 08619 ------------------------------------------------------------------------ Monetary NAMI 1235 $2,500 3/8/2017 Silver Mercer Whiteho sponsor NJ rse 2017 Mercerv NAMIWalks ille Mercer Road County, NJ Bldg. May 6, 2017 C, Suite 303 Hamilto n, NJ 08619 ------------------------------------------------------------------------ Monetary NAMI 85 N. $1,000 10/5/2017 NAMIWalks NH New State 2017 Hampsh Street ire Concord , NH 03301 ------------------------------------------------------------------------ Monetary NAMI 1538 $7,500 8/29/2017 1-on-1 New Louisia Education Orlean na Ave. for People s New Living with Orleans Schizoaffec , LA tive 70115 Disorder/ Schizophren ia and Their Loved Ones/ Caregivers ------------------------------------------------------------------------ Monetary NAMI of 115 $8,000 10/3/2017 Living Room DuPage North Program County County Illino Farm is Road Wheaton , IL 60187 ------------------------------------------------------------------------ Monetary NAMI of 2701 $3,000 10/13/2017 Compeer Johnso Rochest connects n er Ave. with Local County Iowa Businesses dba City, to Increase Compee IA Volunteeris r of 52245 m and Johnso Visibility n County ------------------------------------------------------------------------ Monetary NAMI of One $3,000 9/29/2017 NAMI Peer-to- Lake Victori Peer County a Sq., Recovery Ste. Education 260 Program Painesv ille, OH 44077 ------------------------------------------------------------------------ Monetary NAMI of One $1,500 8/11/2017 NAMI Lake Lake Victori County County a Sq., Strides for Ste. Awareness 260 NAMI Walk Painesv ille, OH 44077 ------------------------------------------------------------------------ Monetary NAMI of 100 W, $1,000 1/31/2017 Bronze PA Main sponsor Montgo St. NAMIWalks mery Suite Greater County 204 Philadelphi Lansdal a May 6, e, PA 2017 19446 ------------------------------------------------------------------------ Monetary NAMI of 4055 $3,500 9/29/2017 Hope for Southw Executi Recovery est ve Park Ohio Drive, Suite 450 Cincinn ati, OH 45241 ------------------------------------------------------------------------ Monetary NAMI 3037 NW $1,000 5/9/2017 NAMI Walks Oklaho 63RD, Oklahoma ma SUITE 104W Oklahom a City, OK 73116 ------------------------------------------------------------------------ Monetary NAMI 1750 S. $1,000 5/4/2017 2017 St. Brentwo NAMIWALKS Louis od St. Louis Blvd. Suite 511 St. Louis, MO 63144 ------------------------------------------------------------------------ Monetary NAMI P.O. Box $1,000 9/7/2017 13th Annual Summit 462, NAMIWalks County Cuyahog Summit a Falls County 2017 OH 44222 Akron, OH 44311 ------------------------------------------------------------------------ Monetary NAMI 5251 $1,000 5/31/2017 NAMIWalks Ventur Verdugo event in a Way, #K Ventura County P.O. County, CA Box 1613 Camaril lo, CA 93011 ------------------------------------------------------------------------ Monetary NAMI 217 $1,000 8/30/2017 NAMIWalks Waukes Wiscons Waukesha ha in Ave Suite 300 Waukesh a, WI 53186 ------------------------------------------------------------------------ Monetary NAMI 217 $1,000 8/11/2017 Crisis Waukes Wiscons Interventio ha in Ave n Training Suite for Law 300 Enforcement Waukesh a, WI 53186 ------------------------------------------------------------------------ Monetary Nationa 1851 $2,500 5/31/2017 2017 NAMI l Heritag California Allian e Way, Annual ce for Suite Conference the 150 Mental Sacrame ly Ill nto, CA 95815 ------------------------------------------------------------------------ Monetary Nationa 576 $1,500 3/20/2017 2017 NAMI l Farming Connecticut Allian ton Walk ce for Avenue the Hartfor Mental d, CT ly Ill 06105 ------------------------------------------------------------------------ Monetary Nationa 5095 $1,000 3/20/2017 NAMIWalks/ l Murphy Run San Allian Canyon Diego ce for Road, County the Suite Mental 320 San ly Ill Diego, CA 92123 ------------------------------------------------------------------------ Monetary Nationa 1562 $1,000 1/31/2017 Bronze l Route sponsor Allian 130 2017 ce for North NAMIWalks the Brunswi New Jersey Mental ck, NJ ``Building ly Ill 08902 Better Lives''--Ma y 13, 2017 ------------------------------------------------------------------------ Monetary Nationa 800 $3,500 8/29/2017 Project ADD l Transfe Advocating Allian r Road for Dual ce for #31 St. Diagnosis the Paul, Mental MN ly Ill 55114 ------------------------------------------------------------------------ Monetary Nationa 3440 $1,000 4/21/2017 NAMIWalks l Viking Northern Allian Drive, California ce for Suite the 104A Mental Sacrame ly Ill nto, CA 95827 ------------------------------------------------------------------------ Monetary Nationa PO Box $1,000 8/29/2017 NAMI l 550039 Birmingham Allian Birming 2017 Walk ce for ham, AL for Mental the 35255- Health Mental 0039 ly Ill ------------------------------------------------------------------------ Monetary Nationa 3803 N. $50,000 10/3/2017 General l Fairfax mission Allian Drive support ce for Suite the 100 Mental Arlingt ly Ill on, VA 22203 ------------------------------------------------------------------------ Monetary Nationa 1801 W $8,000 11/16/2017 Honest, l Warner Open, Allian Ave, Proud: ce for Suite Addressing the 202 Stigma Mental Chicago Among the ly Ill , IL Incarcerate 60613 d Population ------------------------------------------------------------------------ Monetary Nationa 1562, $2,500 10/13/2017 Annual l Route Conference- Allian 130 -Honoring ce for North The Past, the Brunswi Embracing Mental ck, NJ The ly Ill 08902 Present, Looking To The Future ------------------------------------------------------------------------ Monetary Nationa 3200 S. $1,000 1/31/2017 Bronze l 3rd sponsor Allian Street, 2017 NAMI ce for Unit 6 Walk of the Milwauk Greater Mental ee, WI Milwaukee-- ly Ill 53207 May 20, 2017 ------------------------------------------------------------------------ Monetary Nationa 218 West $5,000 10/19/2017 NAMI l Lawrenc Illinois--G Allian e rassroots ce for Springf Advocacy the ield, Capacity Mental IL Project ly Ill 62704 ------------------------------------------------------------------------ Monetary Nationa P.O. Box $1,000 10/11/2017 Mental l 4096 Health Allian Alvin, Education ce for TX Conference- the 77512 -May 2018 Mental ly Ill ------------------------------------------------------------------------ Monetary Nationa 3803 N. $75,000 12/18/2017 NAMI 2018 l Fairfax CIT/ Allian Drive Criminal ce for Suite Justice the 100 Enhancement Mental Arlingt Initiative ly Ill on, VA 22203 ------------------------------------------------------------------------ Monetary Nationa 3803 N. $50,000 12/18/2017 NAMI l Fairfax HelpLine Allian Drive 2018 ce for Suite the 100 Mental Arlingt ly Ill on, VA 22203 ------------------------------------------------------------------------ Monetary Nationa 99 Pine $5,000 10/27/2017 Intervention l St. , Allian Suite Engagement, ce for 105 Implementat the Albany, ion: Three Mental NY Pronged ly Ill 12207 Approach to Sustainable Mental Health Recovery ------------------------------------------------------------------------ Monetary Nationa P.O. Box $1,000 10/19/2017 12th Annual l 24128 NAMI Allian 117 Lowcountry ce for William Walk the Hilton Mental Parkway ly Ill , Suite K Hilton Head Island, SC 29925 ------------------------------------------------------------------------ Monetary Nationa 4701 SE $2,500 8/23/2017 NAMI Oregon l 24th Mental Allian Ave., Health ce for Suite E Education the Portlan and Support Mental d, OR Programs ly Ill 97202 for Recovery and Wellness ------------------------------------------------------------------------ Monetary Nationa 10630 $1,000 5/9/2017 2017 NAMI l Little Walks Allian Patuxen Maryland ce for t the Parkway Mental Columbi ly Ill a, MD 21044 ------------------------------------------------------------------------ Monetary Nationa 2059 $2,000 5/31/2017 Dane County l Atwood Crisis Allian Ave, Interventio ce for Floor 4 n Team the Madison (CIT) Mental , WI Program ly Ill 53704 ------------------------------------------------------------------------ Monetary Nationa 2059 $1,000 5/31/2017 NAMIWalks l Atwood Dane County Allian Ave, 2017 ce for Floor 4 the Madison Mental , WI ly Ill 53704 ------------------------------------------------------------------------ Monetary Nationa 309 West $1,000 5/5/2017 NAMI Walks l Millbro North Allian ok Rd, Carolina ce for Suite the 121 Mental Raleigh ly Ill , NC 27609 ------------------------------------------------------------------------ Monetary Nationa 2012 $5,000 8/29/2017 Mental l West Illness Allian 25th Peer ce for Street, Support and the #600 Education Mental Clevela ly nd, OH Ill--G 44113 reater Clevel and ------------------------------------------------------------------------ Monetary Nationa 2012 $1,000 8/29/2017 NAMIWalks l West 2017 Allian 25th ce for Street, the #600 Mental Clevela ly nd, OH Ill--G 44113 reater Clevel and ------------------------------------------------------------------------ Monetary Nationa 505 8th $1,000 5/4/2017 NAMIWalks l Avenue, NYC 2017 Allian Ste. Walk/Run ce for 1103 for Mental the New Health Mental York, ly Ill NY of New 10018 York City ------------------------------------------------------------------------ Monetary Nationa 154 $1,000 10/2/2017 NAMIWalks l Waterma Rhode Allian n St., Island 2017 ce of Suite Mental 5B Illnes Provide s nce, RI 02906 ------------------------------------------------------------------------ Monetary Nationa 5963 $1,000 8/11/2017 NAMIWalks l Boymel Butler Allian Dr. County ce on Fairfie Mental ld, OH Illnes 45014 s ------------------------------------------------------------------------ Monetary Nationa P.O. Box $6,000 4/21/2017 General l Art 350891 mission Exhibi Miami, support tions FL of the 33135 Mental ly Ill, Inc. ------------------------------------------------------------------------ Monetary Nationa 8321 Old $30,000 12/28/2017 TakeIt2Heart l Courtho TM--An e- Blood use Rd. Health Clot Suite Anticoagula Allian 255 110 tion ce N. Management Washing Education ton Program St., Focused on Suite AFib 255 Awareness Rockvil and le, MD Lifestyle 20850 Issues Vienna, Encountered VA by AFib 22182 Patients and their Non-Medical Caregivers ------------------------------------------------------------------------ Monetary Nationa 1100 $10,000 10/25/2017 2017 Science l 17th and Coalit Street, Leadership ion NW Symposium for Suite Women 500 with Washing Heart ton, DC Diseas 20036 e, Inc. ------------------------------------------------------------------------ Monetary Nationa 1400 K $85,000 12/18/2017 Medication l Street Adherence Counci NW Learning l for Washing Community Behavi ton, DC oral 20005 Health ------------------------------------------------------------------------ Monetary Nationa 1400 K $85,000 12/18/2017 Policy l Street Action Counci NW Center l for Washing Behavi ton, DC oral 20005 Health ------------------------------------------------------------------------ Monetary Nationa 949 West $7,500 12/4/2017 ACE and STEM l State Program, Junior St. plus tennis Tennis Trenton and , NJ Learni 08618 ng of Trento n ------------------------------------------------------------------------ Monetary Nationa 9707 E $25,000 12/22/2017 National l Easter Stroke Stroke Lane, Awareness Associ Suite B Month ation Centenn ial, CO 80112 ------------------------------------------------------------------------ Monetary New 275 Rt. $4,000 5/24/2017 NJPC Jersey 10 East Professiona Parent Suite l Parent s 220-414 Advocacy Caucus Succasu Training nna, NJ 07876 ------------------------------------------------------------------------ Monetary North 368 $10,000 12/22/2017 NATF Spring Americ Boylsto Patient an n St. Program Thromb Brookli osis ne, MA Forum 02445 ------------------------------------------------------------------------ Monetary North 368 $20,000 12/22/2017 VTE Support Americ Boylsto Group an n St. Project Thromb Brookli osis ne, MA Forum 02445 ------------------------------------------------------------------------ Monetary Northea 2900 $2,500 4/4/2017 Day of st Conner Restoration Guidan Avenue, ce Buildin Center g A Detroit , MI 48215 ------------------------------------------------------------------------ Monetary Passage P.O. Box $7,500 12/4/2017 Support for Theatr 967 Passage e Trenton Theatre's Compan , NJ Education y, 08605 programming Inc. the State Street Project ------------------------------------------------------------------------ Monetary Peggie 93 $75 3/9/2017 Employee and Patrici directed Paul a Place donation in Shevli Media, lieu of n PA company Family 19063 holiday Founda gift tion ------------------------------------------------------------------------ Monetary PEI 231 $17,500 10/16/2017 Comprehensiv Kids Lawrenc e Juvenile e Road Offenders Lawrenc Outreach eville, Services NJ (CJOOS) 08648 Program ------------------------------------------------------------------------ Monetary PEI 231 $300 9/29/2017 Costs Kids Lawrenc associated e Road with Lawrenc Janssen eville, Cares NJ Volunteer 08648 Activity--O ctober 13, 2017 ------------------------------------------------------------------------ Monetary People 295 $2,500 12/5/2017 Reading And Eggerts Deeply in Storie Crossin Community: s--Gen g Road A te Y Lawrenc Literature Cuento eville, Project for s, NJ Mercer Inc. 08648 County Youth and Seniors ------------------------------------------------------------------------ Monetary PlanSma 118 West $3,500 3/8/2017 2017 rt NJ State Corporate PlanSma membership rt NJ renewal Trenton donation to , NJ support 08608 efforts around sound land use planning ------------------------------------------------------------------------ Monetary Princet P.O. Box $2,500 12/4/2017 Afterschool on 134 190 Music Girl Nassau Outreach Choir Street Program Princet on, NJ 08542 ------------------------------------------------------------------------ Monetary Princet 45 $4,000 12/12/2017 Supporting on Stockto Family Senior n St Caregivers Resour Princet ce on, NJ Center 08540 ------------------------------------------------------------------------ Monetary Princet P.O. Box $4,000 12/12/2017 PSO BRAVO! on 250, TRENTON Sympho 575 Youth ny Ewing Education Orches Street Initiative tra Princet on, NJ 08540 ------------------------------------------------------------------------ Monetary Princet 13 $7,500 12/5/2017 Summer on- Roszel Bridge Blairs Road 2018--Trent town Suite on Center C204A , Inc. Princet on, NJ 08540 ------------------------------------------------------------------------ Monetary Printma 440 $15,000 12/18/2017 Combat Paper king River NJ Center Road of New Branchb Jersey urg, NJ 08876 ------------------------------------------------------------------------ Monetary Public 825 $7,500 7/25/2017 NJTV's In Media Eighth Your NJ, Avenue Neighborhoo Inc. New d Trenton York, NY 10019 ------------------------------------------------------------------------ Monetary Rainier 12020 $750 4/20/2017 Employee Therap 123rd directed eutic Ave. SE donation in Riding Rainier lieu of Rainier company , WA holiday 98576 gift ------------------------------------------------------------------------ Monetary Raritan P.O. Box $7,000 12/5/2017 WaterWays Headwa 273 Environment ters Gladsto al Associ ne, NJ Education ation 07934 Program ------------------------------------------------------------------------ Monetary Raritan 118 $20,000 10/30/2017 Nursing Valley Lamingt Scholarship Commun on Rd. s ity Branchb ($12,500); Colleg urg, NJ Galileo e 08876 Scholars Program ($5,000); Textbook Scholarship s ($2,500) ------------------------------------------------------------------------ Monetary Regions 640 $15,000 5/24/2017 Make It OK Hospit Jackson al Street, Founda MS tion 11202C St. Paul, MN 55101 ------------------------------------------------------------------------ Monetary Rescue 98 $25,000 10/16/2017 Emergency Missio Carroll Services n of Street Program Trento P.O. n Box 790 Trenton , NJ 08605- 0790 ------------------------------------------------------------------------ Monetary Rider 2083 $19,500 10/30/2017 Summer STEM Univer Lawrenc ($12,000); sity eville Scholarship Rd. Support Lawrenc ($5,000); eville, Shakespeari NJ an at Rider 08648 ($2,500) ------------------------------------------------------------------------ Monetary Riverbe P.O. Box $5,000 8/14/2017 InSHAPE nd 2032 Program Commun Concord ity , NH Mental 03302- Health 2032 , Inc. ------------------------------------------------------------------------ Monetary Riversi P.O. Box $10,000 12/4/2017 Riverside de 650 Symphonia Sympho Lambert Senior nia, ville, Outreach Inc. NJ Program 08530 ------------------------------------------------------------------------ Monetary Robert One $8,500 12/18/2017 Girls to Wood Hamilto Women: Myth Johnso n vs. Reality n Health Hamilt Place on Hamilto Founda n, NJ tion 08690 ------------------------------------------------------------------------ Monetary Rush 2000 $2,500 10/16/2017 Fox Valley Copley Ogden Heart Fund Founda Ave. tion Aurora, IL 60504 ------------------------------------------------------------------------ Monetary Rutgers 7 $300 9/29/2017 Costs Univer College associated sity Avenue with Founda Winants Janssen tion Hall Cares New Volunteer Brunswi Activity--S ck, NJ eptember 08901 20, 2017 ------------------------------------------------------------------------ Monetary Rutgers 4 $8,546 12/18/2017 Corporate Univer Hunting Social sity ton Responsibil School Street ity of New Fellowship Commun Brunswi icatio ck, NJ n, 08901-1 Inform 071 ation and Librar y Studie s ------------------------------------------------------------------------ Monetary SAFE in 46 East $300 9/29/2017 Costs Hunter Main associated don Street with Fleming Janssen ton, NJ Cares 08822 Volunteer Activity--S eptember 19, 2017 ------------------------------------------------------------------------ Monetary SAFE in 46 East $300 9/29/2017 Costs Hunter Main associated don Street with Fleming Janssen ton, NJ Cares 08822 Volunteer Activity--S eptember 18, 2017 ------------------------------------------------------------------------ Monetary San P.O. Box $5,000 8/15/2017 Behavioral Franci 410836 Health sco San Court's Genera Francis Motivationa l co, CA l Hospit 94110 Incentives al Program Founda tion ------------------------------------------------------------------------ Monetary SAVE A 900 $300 9/29/2017 Costs Friend Herront associated to own with Homele Road Janssen ss Princet Cares Animal on NJ Volunteer s 08540 Activity--S eptember 22, 2017 ------------------------------------------------------------------------ Monetary Schizop P.O. Box $15,000 12/12/2017 HVoS hrenia 94122 (Hearing And Houston Voices of Relate , TX Support) d 77094 Perception Disord Changing ers Experientia Allian l ce Of Installatio Americ n and a Scientific Briefing ------------------------------------------------------------------------ Monetary SERV 20 $5,000 10/16/2017 SERV 15th Founda Scotch Annual tion, Road Wellness Inc. Ewing, and NJ Development 08628 Conference ------------------------------------------------------------------------ Monetary SERV 20 $7,500 10/16/2017 SERV Founda Scotch Foundation tion, Road Scholarship Inc. Ewing, Fund NJ 08628 ------------------------------------------------------------------------ Monetary SERV 20 $300 8/24/2017 Costs Founda Scotch associated tion, Road with Inc. Ewing, Janssen NJ Cares 08628 Volunteer Activity--A ugust 20, 2017 ------------------------------------------------------------------------ Monetary Shannon 36 $500 12/5/2017 Shannon Daley Indian Daley Memori Run Memorial al P.O. Fund Fund Box Charity 1271 Events Whiteho use Station , NJ 08889 ------------------------------------------------------------------------ Monetary The 1920 $2,500 8/14/2017 1920 Club Sharin 10th Art Program g Avenue Place, South Inc. P.O. Box 59455 Birming ham, AL 35255 ------------------------------------------------------------------------ Monetary Sisters 1201 $5,000 10/30/2017 Pearl Grace Networ Hamilto Memorial k of n Golf Centra Street Tournament l New Somerse Jersey t, NJ 08873 ------------------------------------------------------------------------ Monetary Somerse 190 Lord $300 8/24/2017 Costs t Stirlin associated County g Road with Park Basking Janssen Founda Ridge, Cares tion NJ Volunteer 07920 Activity--S eptember 15, 2017 ------------------------------------------------------------------------ Monetary Special 1 Eunice $7,500 12/12/2017 Special Olympi Kennedy Olympics cs New Shriver New Jersey-- Jersey Way Camp Lawrenc Shriver e Townshi p, NJ 08648 ------------------------------------------------------------------------ Monetary St. One $20,000 12/4/2017 Providing Mary Summit Food for Medica Square, Underserved l Suite Children in Center 300 Bucks Founda 1717 County: The tion Langhor St. Mary ne- Backpacks Newtown for Kids Rd. Program Langhor ne, PA 19047 ------------------------------------------------------------------------ Monetary Stony 31 Titus $15,000 12/18/2017 StreamWatch: Brook Mill Citizen Millst Road Scientists one Penning Monitoring Waters ton, NJ Water hed 08534 Quality in Associ Central New ation Jersey ------------------------------------------------------------------------ Monetary TASK, 72\1/2\ $25,000 10/30/2017 Meal Service Inc. Escher Program Street Trenton , NJ 08609 ------------------------------------------------------------------------ Monetary The Arc 180 $5,000 12/18/2017 The Arc Mercer Ewingvi Mercer and lle Medina Road Community Ewing, Clinic NJ 08683 ------------------------------------------------------------------------ Monetary The Paul $5,000 10/27/2017 Communiversi Arts Robeson ty ArtsFest Counci Center 2018 l of for the Prince Arts ton 102 Withers poon Street Princet on, NJ 08542 ------------------------------------------------------------------------ Monetary The Paul $10,000 10/27/2017 Arts Council Arts Robeson of Counci Center Princeton l of for the Community Prince Arts Outreach ton 102 Programs Withers poon Street Princet on, NJ 08542 ------------------------------------------------------------------------ Monetary The Paul $300 9/29/2017 Costs Arts Robeson associated Counci Center with l of for the Janssen Prince Arts Cares ton 102 Volunteer Withers Activity--S poon eptember Street 11, 2017 Princet on, NJ 08542 ------------------------------------------------------------------------ Monetary The 2020 $2,000 11/6/2017 Art Classes Center Burnt for for Mills Children Contem Road with Autism porary Bedmins Spectrum Art ter, NJ Disorder 07882 and Other Special Needs ------------------------------------------------------------------------ Monetary The 19B $300 8/24/2017 Costs Center Dellwoo associated For d Lane with Great Somerse Janssen Expect t, NJ Cares ations 08873 Volunteer Activity--S eptember 19, 2017 ------------------------------------------------------------------------ Monetary The 19B $12,000 9/15/2017 Adult Center Dellwoo Women's For d Lane Program Great Somerse Expect t, NJ ations 08873 ------------------------------------------------------------------------ Monetary The 205 $7,500 10/30/2017 The Edinburg Edinbu Burling Center Jail rg ton Diversion Center Road Program Lexingt on, MA 01730 ------------------------------------------------------------------------ Monetary The 401 $1,000 5/4/2017 8th Annual Mental Cypress Run/Walk Health Street for Mental Center Manches Health Of ter, NH Greate 03103 r Manche ster ------------------------------------------------------------------------ Monetary The 400 $300 9/29/2017 Costs Pennsb Pennsbu associated ury ry with Societ Memoria Janssen y l Rd. Cares Morrisv Volunteer ille, Activity--S PA eptember 19067 25, 2017 ------------------------------------------------------------------------ Monetary The P.O. Box $9,000 12/5/2017 Opera for Prince 2063 All ton Princet Festiv on, NJ al 08543 ------------------------------------------------------------------------ Monetary The 243 $5,000 12/14/2017 Sensory Roxey North Friendly Ballet Union Performance Compan Street s at y, Lambert Trenton Inc. ville, Psychiatric NJ Hospital 08530 and The College of New Jersey ------------------------------------------------------------------------ Monetary The 4101 $20,000 9/26/2017 MindStrong Thresh North olds Ravensw ood Avenue Chicago , IL 60613 ------------------------------------------------------------------------ Monetary The 100 $10,000 8/30/2017 Farm Based Willia Gould Psychiatric m J. Road Rehabilitat Gould P.O. ion and Associ Box 157 Recovery ates, Montere Inc. y, MA 01245 ------------------------------------------------------------------------ Monetary Thomas 111 West $15,000 12/18/2017 Scholarships Edison State for Nursing State Street Students Colleg Trenton Enrolled in e , NJ the Founda 08608 Accelerated tion Second Degree BSN Program at the W. Cary Edwards School of Nursing at Thomas Edison State University. ------------------------------------------------------------------------ Monetary TPTO 51 South $1,500 10/30/2017 2018 Inc--T Timberl Timberlane imberl ane Science and ane Drive Engineering Parent Penning Fair Teache ton, NJ r 08534 Organi zation ------------------------------------------------------------------------ Monetary Trenton 471 $7,500 12/18/2017 Trenton Childr Parkway Children's en's Avenue Chorus Chorus Trenton , Inc. , NJ 08618 ------------------------------------------------------------------------ Monetary Trenton P.O. Box $8,500 11/6/2017 Second Commun 5206 Semester ity Trenton Programs, Music , NJ Trenton School 08638 Music Makers ------------------------------------------------------------------------ Monetary Trenton 635 $5,000 12/4/2017 Trenton Educat South Education ion Clinton Dance Dance Avenue Institute Instit Trenton (TEDI) ute , NJ 08611 ------------------------------------------------------------------------ Monetary Trenton 218 $19,000 10/27/2017 Wheels to Health North Wellness Team Broad Inc. Street Trenton , NJ 08608 ------------------------------------------------------------------------ Monetary Trinity 22 $7,500 10/30/2017 TCS General Counse Stockto Counseling ling n and Servic Street Prevention es Princet Programming on, NJ 08540 ------------------------------------------------------------------------ Monetary Tuscalo P.O. Box $1,000 5/4/2017 Hot Hundred osa 2322 2017 Mental Tuscalo Health osa, AL Allian 35403 ce ------------------------------------------------------------------------ Monetary Twiligh P.O. Box $7,500 10/30/2017 Simple Needs t Wish 1042 Wish Founda Doylest Granting tion own, PA Program 18901 ------------------------------------------------------------------------ Monetary UIH 4 North $10,000 12/18/2017 Healthy Family Broad Relationshi Partne Street ps, Healthy rs Suite Choices 2R Trenton , NJ 08608 ------------------------------------------------------------------------ Monetary UIH 4 North $20,000 12/18/2017 Community of Family Broad Health for Partne Street Men, Year 4 rs Suite 2R Trenton , NJ 08608 ------------------------------------------------------------------------ Monetary United 60 Park $7,500 10/30/2017 UNCF Negro Place Scholarship Colleg Suite e Fund 406 Newark, NJ 07102 ------------------------------------------------------------------------ Monetary United 413 Hood $85,000 9/29/2017 Fresh Way of Blvd Connect Bucks Fairles program County s Hills, PA 19030 ------------------------------------------------------------------------ Monetary United 413 Hood $42,500 9/29/2017 Emergency Way of Blvd Needs Bucks Fairles program County s Hills, PA 19030 ------------------------------------------------------------------------ Monetary United 3150 $85,000 10/30/2017 United Way Way of Brunswi of Greater Greate ck Pike Mercer r Suite County Mercer 230 Minority County Lawrenc and eville, Multicultur NJ al Health 08648 Initiative ------------------------------------------------------------------------ Monetary United 3150 $920 12/4/2017 Costs Way of Brunswi associated Greate ck Pike with r Suite Janssen Mercer 230 Cares County Lawrenc Volunteer eville, Activity--S NJ eptember 08648 26, 2017 ------------------------------------------------------------------------ Monetary UrbanPr 801 West $2,770 12/12/2017 Mindfulness omise State Pilot Intern Street Program ationa Trenton l, , NJ Inc. 08618 ------------------------------------------------------------------------ Monetary Valeo 5401 SW $3,500 9/19/2017 Vocational Behavi 7th Empowerment oral Street Photovoice Health Topeka, Care, KS Inc. 66606 ------------------------------------------------------------------------ Monetary Visions 49 $7,500 12/12/2017 Street-Smart and Brahma HIV/AIDS Pathwa Ave. ys Bridgew ater, NJ 08807 ------------------------------------------------------------------------ Monetary Visions 49 $300 11/6/2017 Costs and Brahma associated Pathwa Ave. with ys Bridgew Janssen ater, Cares NJ Volunteer 08807 Activity ------------------------------------------------------------------------ Monetary Volunte 12 $9,000 12/1/2017 SkillsConnec er Stockto t Connec n t Street Princet on, NJ 08540 ------------------------------------------------------------------------ Monetary Washing P.O. Box $750 10/16/2017 Revolutionar ton 83 y War Crossi Titusvi Weekend ng lle, NJ Park 08560 Associ ation, Inc. ------------------------------------------------------------------------ Monetary We Care 3035 $1,500 5/31/2017 ArtWORK Arts Wilming ton Pike Ketteri ng, OH 45429 ------------------------------------------------------------------------ Monetary West P.O. Box $5,000 12/5/2017 Excellence Windso 280 in r West Education, Plains Windsor and boro , NJ Innovation Educat 08550 Fair 2018 ion Founda tion ------------------------------------------------------------------------ Monetary Westmor 100 $75 3/22/2017 Employee eland Devonsh directed County ire donation in Food Drive lieu of Bank, Delmont company Inc. , PA holiday 15626- gift 1607 ------------------------------------------------------------------------ Monetary Womansp 1530 $7,500 12/5/2017 Safe House ace Brunswi (Emergency ck Ave. Shelter) Lawrenc and eville, Barbara's NJ House 08648 (Transition al Housing): Supporting Women and Children Impacted by Domestic Violence ------------------------------------------------------------------------ Monetary Womansp 1530 $300 9/29/2017 Costs ace Brunswi associated ck Ave. with Lawrenc Janssen eville, Cares NJ Volunteer 08648 Activity--O ctober 2, 2017 ------------------------------------------------------------------------ Monetary Womansp 1530 $300 9/29/2017 Costs ace Brunswi associated ck Ave. with Lawrenc Janssen eville, Cares NJ Volunteer 08648 Activity--O ctober 5, 2017 ------------------------------------------------------------------------ Monetary Woods 40 $4,000 12/12/2017 Yoga at Servic Martin Woods es Gross Services: A Founda Drive, Recreationa tion P.O. l Program Box 36 for People Langhor with ne, PA Special 19047 Needs ------------------------------------------------------------------------ Monetary Young 349 W. $3,500 12/18/2017 Early Schola State Literacy rs' St Engagement Instit Trenton and ute , NJ Development 08618 ------------------------------------------------------------------------ Product AmeriCa 88 $493,168 1/3/2017 Product res Hamilto donation Founda n Ave. for tion Stamfor humanitaria d, CT n 06902 assistance in Dominican Republic, Nicaragua, West Bank, and U.S. ------------------------------------------------------------------------ Product AmeriCa 88 $145,709 1/6/2017 Product res Hamilto donation Founda n Ave. for tion Stamfor humanitaria d, CT n 06902 assistance in Nicaragua, Dominican Republic, West Bank, and U.S. ------------------------------------------------------------------------ Product AmeriCa 88 $257,792 1/9/2017 Product res Hamilto donation Founda n Ave. for tion Stamfor humanitaria d, CT n 06902 assistance in Nicaragua, Dominican Republic, West Bank, and U.S. ------------------------------------------------------------------------ Product AmeriCa 88 $100,065 2/16/2017 Product res Hamilto donation Founda n Ave. for tion Stamfor humanitaria d, CT n 06902 assistance in St. Lucia, Nicaragua, Republic, and Lebanon ------------------------------------------------------------------------ Product AmeriCa 88 $1,185,644 2/16/2017 Product res Hamilto donation Founda n Ave. for tion Stamfor humanitaria d, CT n 06902 assistance in U.S. clinics ------------------------------------------------------------------------ Product AmeriCa 88 $4,640 3/13/2017 Product res Hamilto donation Founda n Ave. for tion Stamfor humanitaria d, CT n 06902 assistance in Puerto Rico ------------------------------------------------------------------------ Product AmeriCa 88 $1,281,296 3/20/2017 Product res Hamilto donation Founda n Ave. for tion Stamfor humanitaria d, CT n 06902 assistance in Tanzania, West Bank, Gaza, St. Lucia, Lebanon, Dominican Republic, Colombia, Nicaragua, and U.S. ------------------------------------------------------------------------ Product AmeriCa 88 $91,239 3/20/2017 Product res Hamilto donation Founda n Ave. for tion Stamfor humanitaria d, CT n 06902 assistance in Nicaragua and Colombia ------------------------------------------------------------------------ Product AmeriCa 88 $1,077,988 4/11/2017 Product res Hamilto donation Founda n Ave. for tion Stamfor humanitaria d, CT n 06902 assistance in Gaza, West Bank, Colombia, and U.S. ------------------------------------------------------------------------ Product AmeriCa 88 $181,140 4/11/2017 Product res Hamilto donation Founda n Ave. for tion Stamfor humanitaria d, CT n 06902 assistance in St. Lucia, Afghanistan , and Colombia ------------------------------------------------------------------------ Product AmeriCa 88 $191,031 5/23/2017 Product res Hamilto donation Founda n Ave. for tion Stamfor humanitaria d, CT n 06902 assistance in Nicaragua, Dominican Republic, and St. Lucia ------------------------------------------------------------------------ Product AmeriCa 88 $72,844 5/23/2017 Product res Hamilto donation Founda n Ave. for tion Stamfor humanitaria d, CT n 06902 assistance in Nicaragua. ------------------------------------------------------------------------ Product AmeriCa 88 $871,110 6/22/2017 Product res Hamilto donation Founda n Ave. for tion Stamfor humanitaria d, CT n 06902 assistance in Dominican Republic, St. Lucia, and West Bank ------------------------------------------------------------------------ Product AmeriCa 88 $185,347 6/22/2017 Product res Hamilto donation Founda n Ave. for tion Stamfor humanitaria d, CT n 06902 assistance in Dominican Republic, and West Bank ------------------------------------------------------------------------ Product AmeriCa 88 $9,583,716 7/17/2017 Product res Hamilto donation Founda n Ave. for tion Stamfor humanitaria d, CT n 06902 assistance in Kyrgyzstan ------------------------------------------------------------------------ Product AmeriCa 88 $149,758 7/19/2017 Product res Hamilto donation Founda n Ave. for tion Stamfor humanitaria d, CT n 06902 assistance in St. Lucia ------------------------------------------------------------------------ Product AmeriCa 88 $91,601 8/21/2017 Product res Hamilto donation Founda n Ave. for tion Stamfor humanitaria d, CT n 06902 assistance in United States ------------------------------------------------------------------------ Product AmeriCa 88 $259,213 8/21/2017 Product res Hamilto donation Founda n Ave. for tion Stamfor humanitaria d, CT n 06902 assistance in United States ------------------------------------------------------------------------ Product AmeriCa 88 $383,085 9/27/2017 Pharmaceutic res Hamilto al product Founda n Ave. Donation tion Stamfor for d, CT humanitaria 06902 n aid in Gaza, St. Lucia, and Peru ------------------------------------------------------------------------ Product AmeriCa 88 $134,651 9/27/2017 Product res Hamilto donation Founda n Ave. for tion Stamfor humanitaria d, CT n aid for 06902 El Salvador, Peru and St. Lucia ------------------------------------------------------------------------ Product AmeriCa 88 $2,013,098 10/10/2017 Product for res Hamilto humanitaria Founda n Ave. n and tion Stamfor disaster d, CT response in 06902 Houston, Florida and Puerto Rico ------------------------------------------------------------------------ Product AmeriCa 88 $65,375 10/10/2017 Product res Hamilto donation Founda n Ave. for tion Stamfor humanitaria d, CT n and 06902 disaster relief in Houston, Florida, and Puerto Rico ------------------------------------------------------------------------ Product AmeriCa 88 $75,473 10/20/2017 Product res Hamilto donation Founda n Ave. for tion Stamfor humanitaria d, CT n aid in 06902 Nicaragua and US Clinics ------------------------------------------------------------------------ Product AmeriCa 88 $82,469 11/15/2017 Product res Hamilto donation Founda n Ave. for tion Stamfor humanitaria d, CT n aid in US 06902 Clinic Network ------------------------------------------------------------------------ Product AmeriCa 88 $442,409 11/15/2017 Product res Hamilto donation Founda n Ave. for tion Stamfor humanitaria d, CT n aid in 06902 Sierra Leone ------------------------------------------------------------------------ Product AmeriCa 88 $816,348 8/31/2017 Product res Hamilto Donation Founda n Ave. for tion Stamfor Disaster d, CT Response--H 06902 urricane Harvey ------------------------------------------------------------------------ Product AmeriCa 88 $1,320,624 11/17/2017 Product res Hamilto donation Founda n Ave. for tion Stamfor humanitaria d, CT n 06902 assistance in U.S ------------------------------------------------------------------------ Product AmeriCa 88 $504,595 12/5/2017 Product res Hamilto donation Founda n Ave. for tion Stamfor humanitaria d, CT n 06902 assistance in the Dominican Republic ------------------------------------------------------------------------ Product AmeriCa 88 $971,862 12/5/2017 Product for res Hamilto humanitaria Founda n Ave. n tion Stamfor assistance d, CT in the 06902 Dominican Republic ------------------------------------------------------------------------ Product AmeriCa 88 $4,298,976 12/5/2017 Product res Hamilto donation Founda n Ave. for tion Stamfor humanitaria d, CT n 06902 assistance in US Clinic Networks ------------------------------------------------------------------------ Product Catholi 100 Wall $432,510 11/16/2017 Product c Street, donation Medica 9th for l Floor humanitaria Missio New n n York, assistance Board NY in: 10005 Dominican Republic, Haiti and Guatemala ------------------------------------------------------------------------ Product Catholi 100 Wall $566,919 11/16/2017 Product c Street, donation Medica 9th for l Floor humanitaria Missio New n n York, assistance Board NY in: 10005 Dominican Republic, Haiti, and Guatemala ------------------------------------------------------------------------ Product Catholi 100 Wall $68,662 10/20/2017 Product c Street, donation Medica 9th for l Floor humanitaria Missio New n n York, assistance Board NY in the 10005 Dominican Republic, Guatemala and Haiti ------------------------------------------------------------------------ Product Catholi 100 Wall $47,020 9/27/2017 Product c Street, donation Medica 9th for l Floor humanitaria Missio New n aid in n York, the Board NY Dominican 10005 Republic ------------------------------------------------------------------------ Product Catholi 33-01 $1,626,679 7/19/2017 Product c Elevent donation Medica h for l Street humanitaria Missio Long n n Island assistance Board City, in NY Guatemala, Haiti, Dominican Republic, and Nicaragua ------------------------------------------------------------------------ Product Catholi 33-01 $2,839,769 7/19/2017 Product c Elevent donation Medica h for l Street humanitaria Missio Long n n Island assistance Board City, in NY Guatemala, Haiti, Dominican Republic, and Nicaragua ------------------------------------------------------------------------ Product Catholi 100 Wall $129,896 8/21/2017 Product c Street, donation Medica 9th for l Floor humanitaria Missio New n n York, assistance Board NY in 10005 Dominican Republic, and Nicaragua ------------------------------------------------------------------------ Product Catholi 100 Wall $2,091,213 8/21/2017 Product c Street, donation Medica 9th for l Floor humanitaria Missio New n n York, assistance Board NY in 10005 Dominican Republic, Haiti, and Nicaragua ------------------------------------------------------------------------ Product Catholi 33-01 $698,911 6/22/2017 Product c Elevent donation Medica h for l Street humanitaria Missio Long n n Island assistance Board City, in NY Guatemala, El Salvador, Nicaragua, Haiti, and Jamaica ------------------------------------------------------------------------ Product Catholi 33-01 $537,473 6/22/2017 Product c Elevent donation Medica h for l Street humanitaria Missio Long n n Island assistance Board City, in NY Dominican Republic, Haiti, Guatemala, Jamaica, and El Salvador ------------------------------------------------------------------------ Product Catholi 33-01 $597,003 4/10/2017 Product c Elevent donation Medica h for l Street humanitaria Missio Long n n Island assistance Board City, in El NY Salvador, Haiti, and Nicaragua ------------------------------------------------------------------------ Product Catholi 33-01 $565,051 4/10/2017 Product c Elevent donation Medica h for l Street humanitaria Missio Long n n Island assistance Board City, in El NY Salvador, Haiti, Honduras, Nicaragua, and Guatemala ------------------------------------------------------------------------ Product Catholi 33-01 $610,715 5/23/2017 Product c Elevent donation Medica h for l Street humanitaria Missio Long n n Island assistance Board City, in NY Tanzania, Guatemala, Jamaica, and Dominican Republic ------------------------------------------------------------------------ Product Catholi 33-01 $716,298 5/23/2017 Product c Elevent donation Medica h for l Street humanitaria Missio Long n n Island assistance Board City, in NY Dominican Republic, Tanzania, and Guatemala ------------------------------------------------------------------------ Product Catholi 33-01 $1,336,614 3/20/2017 Product c Elevent donation Medica h for l Street humanitaria Missio Long n n Island assistance Board City, in NY Guatemala, El Salvador, and Haiti ------------------------------------------------------------------------ Product Catholi 33-01 $102,932 3/20/2017 Product c Elevent donation Medica h for l Street humanitaria Missio Long n n Island assistance Board City, in NY Guatemala and Haiti ------------------------------------------------------------------------ Product Catholi 33-01 $117,953 2/15/2017 Product c Elevent donation Medica h for l Street humanitaria Missio Long n n Island assistance Board City, in Haiti, NY El Salvador and Honduras ------------------------------------------------------------------------ Product Direct 27 S. La $1,051,504 3/20/2017 Product Relief Patera donation Lane for Santa humanitaria Barbara n , CA assistance 93117 in Honduras, Liberia, Haiti and El Salvador. ------------------------------------------------------------------------ Product Direct 27 S. La $91,239 3/20/2017 Product Relief Patera donation Lane for Santa humanitaria Barbara n , CA assistance 93117 in Haiti and Liberia. ------------------------------------------------------------------------ Product Direct 27 S. La $23,107 2/16/2017 Product Relief Patera donation Lane for Santa humanitaria Barbara n , CA assistance 93117 in Honduras. ------------------------------------------------------------------------ Product Direct 27 S. La $378,636 2/16/2017 Product Relief Patera donation Lane for Santa humanitaria Barbara n , CA assistance 93117 in Honduras. ------------------------------------------------------------------------ Product Direct 27 S. La $2,390,729 4/11/2017 Product Relief Patera donation Lane for Santa humanitaria Barbara n , CA assistance 93117 in Colombia, Sierra Leone, Vanuatu, Ghana, Malawi, Haiti, Nicaragua and U.S. ------------------------------------------------------------------------ Product Direct 27 S. La $249,548 4/11/2017 Product Relief Patera donation Lane for Santa humanitaria Barbara n , CA assistance 93117 in Ghana, Malawi, Sierra Leone, Liberia, Pakistan and U.S. ------------------------------------------------------------------------ Product Direct 27 S. La $804,308 5/23/2017 Product Relief Patera donation Lane for Santa humanitaria Barbara n , CA assistance 93117 in Malawi and Sierra Leone ------------------------------------------------------------------------ Product Direct 27 S. La $209,508 5/23/2017 Product Relief Patera donation Lane for Santa humanitaria Barbara n , CA assistance 93117 in Colombia, Pakistan, Ghana, Malawi, Sierra Leone and Liberia. ------------------------------------------------------------------------ Product Direct 27 S. La $500,169 6/22/2017 Product Relief Patera donation Lane for Santa humanitaria Barbara n , CA assistance 93117 in Jamaica, Nicaragua, Pakistan, and Liberia ------------------------------------------------------------------------ Product Direct 27 S. La $710,949 6/22/2017 Product Relief Patera donation Lane for Santa humanitaria Barbara n , CA assistance 93117 in Jamaica ------------------------------------------------------------------------ Product Direct 27 S. La $1,405,277 7/19/2017 Product Relief Patera donation Lane for Santa humanitaria Barbara n , CA assistance 93117 in Honduras, Colombia, and Pakistan ------------------------------------------------------------------------ Product Direct 27 S. La $1,152,189 7/19/2017 Product Relief Patera Donation Lane for Santa humanitaria Barbara n , CA assistance 93117 in Honduras, Colombia, Pakistan, and USA. ------------------------------------------------------------------------ Product Direct 27 S. La $271,063 9/27/2017 Product Relief Patera donation Lane for Santa humanitaria Barbara n , CA assistance 93117 in Ghana ------------------------------------------------------------------------ Product Direct 27 S. La $61,205 9/27/2017 Product Relief Patera donation Lane for Santa humanitaria Barbara n , CA assistance 93117 in Ghana ------------------------------------------------------------------------ Product Direct 27 S. La $373,326 8/21/2017 Product Relief Patera donation Lane for Santa Humanitaria Barbara n , CA assistance 93117 in the United States ------------------------------------------------------------------------ Product Direct 27 S. La $259,561 8/21/2017 Product Relief Patera donation Lane for Santa Humanitaria Barbara n , CA assistance 93117 in the United States ------------------------------------------------------------------------ Product Direct 27 S. La $239,304 10/23/2017 Product Relief Patera donation Lane for Santa humanitaria Barbara n , CA assistance 93117 in US Clinics ------------------------------------------------------------------------ Product Direct 27 S. La $571,784 12/5/2017 Product Relief Patera donation Lane for Santa humanitaria Barbara n , CA assistance 93117 in Syria ------------------------------------------------------------------------ Product Direct 27 S. La $62,628 10/2/2017 Product Relief Patera donation Lane for Santa humanitaria Barbara n , CA assistance 93117 in Houston, Florida, and Puerto Rico ------------------------------------------------------------------------ Product Direct 27 S. La $3,961,872 11/17/2017 Product Relief Patera donation Lane for Santa humanitaria Barbara n , CA assistance 93117 in Syria ------------------------------------------------------------------------ Product Direct 27 S. La $3,482,171 12/1/2017 Product Relief Patera donation Lane for Santa humanitaria Barbara n , CA assistance 93117 in Syria ------------------------------------------------------------------------ Product Direct 27 S. La $82,127 9/7/2017 Product Relief Patera Donation Lane for Santa Disaster Barbara response--H , CA urricane 93117 Harvey ------------------------------------------------------------------------ Product Direct 27 S. La $494,813 11/16/2017 Product Relief Patera donation Lane for Santa humanitaria Barbara n , CA assistance 93117 in Syria ------------------------------------------------------------------------ Product Direct 27 S. La $224,506 11/16/2017 Product Relief Patera donation Lane for Santa humanitaria Barbara n , CA assistance 93117 in Syria ------------------------------------------------------------------------ Product Direct 27 S. La $161,977 11/16/2017 Product Relief Patera donation Lane for Santa humanitaria Barbara n , CA assistance 93117 in Syria ------------------------------------------------------------------------ Product Direct 27 S. La $31,448 11/16/2017 Product Relief Patera donation Lane for Santa humanitaria Barbara n , CA assistance 93117 in US ------------------------------------------------------------------------ Product Direct 27 S. La $505,634 11/16/2017 Product Relief Patera donation Lane for Santa humanitaria Barbara n , CA assistance 93117 in US Clinics ------------------------------------------------------------------------ Product Heart 1021 $61,205 9/27/2017 Product to Pacific donation Heart Avenue for Intern Kansas humanitaria ationa City, n l KS assistance 66102 in the Dominican Republic ------------------------------------------------------------------------ Product Heart 1021 $224,044 9/27/2017 Product to Pacific donation Heart Avenue for Intern Kansas humanitaria ationa City, n l KS assistance 66102 in the Dominican Republic ------------------------------------------------------------------------ Product Heart 1021 $979,095 6/22/2017 Product to Pacific donation Heart Avenue for Intern Kansas humanitaria ationa City, n l KS assistance 66102 in Honduras. ------------------------------------------------------------------------ Product Heart 1021 $126,867 6/22/2017 Product to Pacific Donation Heart Avenue for Intern Kansas humanitaria ationa City, n l KS assistance 66102 in Honduras. ------------------------------------------------------------------------ Product Heart 1021 $436,536 4/10/2017 Product to Pacific donation Heart Avenue for Intern Kansas humanitaria ationa City, n l KS assistance 66102 in Dominican Republic, Honduras and Papua New Guinea. ------------------------------------------------------------------------ Product Heart 1021 $62,476 4/10/2017 Product to Pacific donation Heart Avenue for Intern Kansas humanitaria ationa City, n l KS assistance 66102 in Honduras and Dominican Republic. ------------------------------------------------------------------------ Product Johnson One $338,315,809 12/31/2017 Patient & Johnson Assistance Johnso & Product n Johnson Donation Patien Plaza t Kilmer Assist Square, ance Suite Founda 130 New tion Brunswi ck, NJ 08933 ------------------------------------------------------------------------ Product MAP 4700 $13,197 2/15/2017 Product Intern Glynco donation ationa Parkway for l Brunswi humanitaria ck, GA n 31525 assistance (Medical Mission Packs). ------------------------------------------------------------------------ Product MAP 4700 $125,592 2/14/2017 Product Intern Glynco donation ationa Parkway for l Brunswi humanitaria ck, GA n 31525 assistance in Sierra Leone ------------------------------------------------------------------------ Product MAP 4700 $108,127 11/16/2017 Product Intern Glynco donation ationa Parkway for l Brunswi humanitaria ck, GA n 31525 assistance in the Eastern Caribbean ------------------------------------------------------------------------ Product MAP 4700 $19,241 7/31/2017 Product Intern Glynco donation ationa Parkway for medical l Brunswi mission ck, GA program 31525 ------------------------------------------------------------------------ Product MAP 4700 $868,191 6/22/2017 Product Intern Glynco donation ationa Parkway for l Brunswi humanitaria ck, GA n 31525 assistance in Haiti, Dominican Republic, and Guatemala. ------------------------------------------------------------------------ Monetary Acercam P.O. Box $5,000 4/26/2017 ContraSIDA iento 3820 Hispan Columbi o de a, SC Caroli 29230 na del Sur ------------------------------------------------------------------------ Monetary ADAP P.O. Box $5,000 4/4/2017 ADAP Advoca 15275 Directory cy Washing ton, DC 20003 ------------------------------------------------------------------------ Monetary ADAP P.O. Box $5,000 10/16/2017 Improving Advoca 15275 Access to cy Washing Care Among ton, DC Formerly 20003 Incarcerate d Populations with HIV/ AIDS under the AIDS Drug Assistance Program (ADAP) ------------------------------------------------------------------------ Monetary African- 1833 $75,000 7/20/2017 Black Americ West Treatment an 8th Advocates Aids Street Network Policy Suite (BTAN) And 200 Los Advanced Traini Angeles Development ng , CA Program Instit 90057 ute ------------------------------------------------------------------------ Monetary AIDS 6260 $3,000 4/4/2017 Linkage to Founda Westpar Care tion k Drive Housto Suite n, 100 Inc. Houston , TX 77057 ------------------------------------------------------------------------ Monetary AIDS 200 W. $50,000 3/1/2017 Ensuring Founda Jackson Access to tion Blvd., HIV of Suite Prevention Chicag 2100 and Care in o Chicago Illinois , IL through 60606 Policy Monitoring and Advocacy ------------------------------------------------------------------------ Monetary AIDS 400 $5,000 4/4/2017 HIV Case Outrea North Management ch Beach at AIDS Center Street Outreach Fort Center Worth, TX 76111 ------------------------------------------------------------------------ Monetary AIDS 820 N. $5,000 8/17/2017 Driving Resour Plankin Innovation ce ton in HIV Center Ave. Healthcare of Milwauk Via ARCW Wiscon ee, WI HIV Medical sin 53203 Centers ------------------------------------------------------------------------ Monetary AIDS 17982 $2,000 5/8/2017 HIV and Servic Sky Hepatitis C es Park Testing Founda Circle, Program tion Suite J Orange Irvine, County CA 92614 ------------------------------------------------------------------------ Monetary AIDS 1101 $200,000 12/19/2017 Transgender United 14th Leadership Street, Initiative NW Suite 300 Washing ton, DC 20005 ------------------------------------------------------------------------ Monetary Alexian 825 W. $5,000 8/17/2017 Transitional Brothe Welling Living rs ton Program for Bonave Chicago Homeless nture , IL Adults with House 60657 HIV/AIDS ------------------------------------------------------------------------ Monetary Alivene 3808 $1,000 7/31/2017 Integrative ss Nicolle Therapies Projec t Ave for People t, Minneap Living with Inc. olis, HIV MN 55409 ------------------------------------------------------------------------ Monetary Aunt 1101 N. $2,500 7/11/2017 Project Rita's Central HIVAZ Founda Ave. tion Suite 212 Phoenix , AZ 85004 ------------------------------------------------------------------------ Monetary Caring PO Box $40,000 3/20/2017 General Ambass 1748 Hepatitis C adors Oregon Program Progra City, Support m, Inc OR 97045 ------------------------------------------------------------------------ Monetary Catholi 119 $5,000 4/4/2017 The Home c Dameron Place Charit Avenue ies of Knoxvil East le, TN Tennes 37917 see, Inc. ------------------------------------------------------------------------ Monetary Center 1115 E. $3,500 10/23/2017 HIV For 12th Prevention Health St. Access and Empowe Austin, Linkage to rment TX Care (CHE) 78702 ------------------------------------------------------------------------ Monetary Central 1785 $5,000 11/13/2017 HIV Testing, Louisi Jackson Counseling, ana Street and Aids Alexand Prevention Suppor ria, LA for African t 71301 American Servic Teens and es Inc Young (CLASS Adults ) ------------------------------------------------------------------------ Monetary Communi 1930 $20,000 12/18/2017 Equal Access ty Martin Educat Luther ion King Jr Group Avenue SE Washing ton, DC 20020 ------------------------------------------------------------------------ Monetary Communi 1930 $20,000 3/13/2017 Access Tools ty Martin Linking All Educat Luther to Services ion King Jr (ATLAS). Group Avenue SE Washing ton, DC 20020 ------------------------------------------------------------------------ Monetary Communi 575 8th $15,000 7/20/2017 HIV Health ty Avenue, Literacy Resear Suite Education ch 502 New and Initia York, Training tive NY for Service on 10018 Providers AIDS, Working Inc. with Vulnerable Populations ------------------------------------------------------------------------ Monetary Frannie 30 $5,000 11/13/2017 Supportive Peabod Danfort Pathways y h St. Along the Center Suite Care Inc. 311 Continuum Portlan (SPACC) d, ME 04101 ------------------------------------------------------------------------ Monetary Gay 446 W. $30,000 12/19/2017 Peer Men's 33rd Navigation Health Street for high- Crisis New risk and York, HIV- NY positive 10001 transgender people ------------------------------------------------------------------------ Monetary Gay 446 W. $30,000 3/1/2017 Peer Men's 33rd Navigation Health Street for high- Crisis New risk and York, HIV- NY positive 10001 transgender people ------------------------------------------------------------------------ Monetary Hepatit 35 East $20,000 2/7/2017 The is C 38th Hepatitis C Mentor Street, Education and Suite and Support Suppor #4G New Group t York, Assistance Group NY Program Inc. 10016 ------------------------------------------------------------------------ Monetary Hepatit 1261 S. $35,000 2/8/2017 General is Jackson Program Educat St., Support ion Suite Projec 201 t Seattle , WA 98144 ------------------------------------------------------------------------ Monetary Howard 4025 N. $25,000 9/29/2017 Patient Brown Sherida Assistance Health n Clinic Center Chicago (PAC): , IL Medication 60613 Therapy Management for Underserved Patients ------------------------------------------------------------------------ Monetary Interna 2200 $75,000 3/1/2017 Conversation tional Pennsyl Maps: Associ vania Patient ation Avenue, Empowerment of NW 4th through HIV Physic Floor Peer ians East Dialogue in in Washing Five U.S. AIDS ton, DC Fast-Track Care 20037 Cities Inc. ------------------------------------------------------------------------ Monetary Legacy 4054 $5,000 4/26/2017 Grace Counse McKinne Project ling y Ave., Program for Center Suite Women 102 Living with Dallas, HIV/AIDS TX 75204 ------------------------------------------------------------------------ Monetary Legal 17 N. $5,000 8/23/2017 Communities Counci State of Color l for Street, Outreach Health Suite Program Justic 900 e Chicago , IL 60602 ------------------------------------------------------------------------ Monetary Lifelon P.O. Box $3,000 3/20/2017 Living g Aids 80547 Positively Allian Seattle ce , WA 98108 ------------------------------------------------------------------------ Monetary Minorit 5149 W. $7,500 4/4/2017 S.T.E.P. y AIDS Jeffers Program Projec on Blvd Strengtheni t Los ng Angeles Treatment , CA Education 90016 for People Living with HIV/AIDS ------------------------------------------------------------------------ Monetary Nationa 580 $175,000 3/16/2017 NATAP HIV l AIDS Broadwa and HCV Treatm y Suite Information ent 1010 and Advoca New Education cy York, Project Projec NY t 10012 ------------------------------------------------------------------------ Monetary Nationa 580 $175,000 12/18/2017 NATAP HIV l AIDS Broadwa and Treatm y Suite Hepatitis ent 1010 Information Advoca New and cy York, Education Projec NY Project t 10012 ------------------------------------------------------------------------ Monetary Nationa 444 $150,000 12/19/2017 Affordable l North Care Act Allian Capitol (ACA), Ryan ce of Street White/ADAP, State NW #339 Public and Washing Policy and Territ ton, DC Technical orial 20001 Assistance, AIDS and the Direct Minority ors Leadership Programs ------------------------------------------------------------------------ Monetary NovaSal 2946 $2,500 11/15/2017 ``Increasing ud, Sleepy Testing and Inc. Hollow Improving Rd. Retention Falls in Care and Church, Access to VA Treatment 22044 for People at Risk or Currently Living with HIV'' ------------------------------------------------------------------------ Monetary Palmett 2638 Two $7,500 7/11/2017 HIV Care o AIDS Notch Coordinatio Life Road, n Program Suppor Suite t 108 Servic Columbi es a, SC 29204 ------------------------------------------------------------------------ Monetary Positiv 785 $2,500 11/13/2017 Integrated e Market Support Resour Street, Services ce 10th Center Floor San Francis co, CA 94103 ------------------------------------------------------------------------ Monetary PowerSo P.O. Box $2,500 10/23/2017 Bridging the urce 12354 Gap Tucson Tucson, , Inc. AZ 85732 ------------------------------------------------------------------------ Monetary Project 273 $10,000 12/18/2017 Mission Inform Ninth Support Street San Francis co, CA 94103 ------------------------------------------------------------------------ Monetary Project 273 $10,000 6/26/2017 Mission Inform Ninth Support for Street Project San Inform Francis co, CA 94103 ------------------------------------------------------------------------ Monetary Project 273 $25,000 6/26/2017 HIV Care Inform Ninth Linkage, Street Retention San and Re- Francis engagement co, CA 94103 ------------------------------------------------------------------------ Monetary Project 273 $25,000 6/26/2017 Policy Inform Ninth Advocacy to Street Protect HIV San Treatment Francis and Care co, CA 94103 ------------------------------------------------------------------------ Monetary Project 2929 NE $5,000 10/16/2017 ``Surviving Link 6TH and of Avenue Thriving; South Wilton Long-term Florid Manors, Survivors a, FL workshops, Inc. 33334 for Gay Men 50 and Over Living with HIV,'' and for our ``Long-term Survivor'' support group. ------------------------------------------------------------------------ Monetary RAIN, 601 E. $20,000 9/29/2017 Free On-Site Inc. 5th Mental Street, Health Suite Services 470 PO for People Box Living with 37190 HIV Charlot te, NC 28202 ------------------------------------------------------------------------ Monetary San 1035 $25,000 6/27/2017 TransLife Franci Market HIV Care sco Street, and Support AIDS Suite Founda 400 San tion Francis co, CA 94103 ------------------------------------------------------------------------ Monetary Service 305 7th $5,000 4/21/2017 SAGEPositive s and Avenue, Advoca 15th cy For Floor Gay New Lesbia York, n NY Bisexu 10001 al and Transg ender Elders Inc. ------------------------------------------------------------------------ Monetary The 17 Davis $65,000 7/20/2017 Ensuring AIDS Bouleva Adequate Instit rd, Funding for ute Suite Domestic 403 HIV/AIDS Suite Programs 403 Tampa, FL 33606 ------------------------------------------------------------------------ Monetary The 17 Davis $65,000 12/19/2017 2018 Federal AIDS Bouleva and State Instit rd, HIV/AIDS ute Suite Policy 403 Issues Suite 403 Tampa, FL 33606 ------------------------------------------------------------------------ Monetary The 64 West $4,000 9/18/2017 ID Inspired Allian 35th Challenge ce for Street, Positi 3rd ve Floor Change New York, NY 10001 ------------------------------------------------------------------------ Monetary The 99 $5,000 7/11/2017 Expansion of Next Bishop Next Step's Step Allen Year-round Fund, Drive Programming Inc. Cambrid for teens ge, MA and young 02138 adults living with HIV. ------------------------------------------------------------------------ Monetary The San P.O. Box $2,500 8/18/2017 Youth Diego 3357 Services LGBT San Commun Diego, ity CA Center 92163 ------------------------------------------------------------------------ Monetary The San P.O. Box $5,000 7/19/2017 HIV services Diego 3357 LGBT San Commun Diego, ity CA Center 92163 ------------------------------------------------------------------------ Monetary The 85 $30,000 12/18/2017 Building Well Norman H.O.P.E. Projec Avenue (Hopeful t P.O. Outreach Box and 220410 Positive Brookly Engagement n, NY for Women 11222 Living with HIV) ------------------------------------------------------------------------ Monetary The 85 $30,000 3/1/2017 HIV Disease Well Norman Awareness/ Projec Avenue Information t P.O. , Community Box Support, 220410 Advocacy Brookly and n, NY Capacity 11222 Building ------------------------------------------------------------------------ Monetary Treatme 90 Broad $15,000 6/26/2017 Ending the nt Street, Epidemic Action Suite Group, 2503 Inc. New York, NY 10004 ------------------------------------------------------------------------ Monetary Univers UCSF $15,000 9/29/2017 UCSF ity Of Allianc Alliance Califo e Health rnia Health Project San Project Mission- Franci 1855 Based sco Folsom Support--Co Street, mmunity Ste. Based 670 Box Intensive 0884 Case San Management Francis for People co, CA Living With 94143 HIV/AIDS ------------------------------------------------------------------------ Monetary Univers 620 W. $2,500 11/13/2017 JACQUES ity Of Lexingt Initiative Maryla on St. Community nd 2nd Outreach Baltim floor Program ore Baltimo Founda re, MD tion, 21201 Inc. ------------------------------------------------------------------------ Monetary US 1300 PA $725,000 12/19/2017 Global Agency Avenue. Public for , NW SA- Health Intern 44 Rm Programs: ationa 475-J Infection l Washing Control Develo ton, DC ($250,000), pment 20523 Anti- Microbial Resistance ($300,000), Pharmacovig ilance ($175,000) ------------------------------------------------------------------------ Monetary Wellnes 2929 NE $2,000 10/16/2017 Prevention s 6 for HIV Center Avenue, Positive of Suite B Heterosexua South Wilton l/Minority Florid Manors, Outreach a, FL Program Inc. 33334 ------------------------------------------------------------------------ Monetary Young 4164 $5,000 7/19/2017 TruEvolution Schola Brockto Community rs For n Ave Wellness Academ Riversi Center ic de, CA Empowe 92501 rment ------------------------------------------------------------------------ Product Johnson One $14,933,212 12/31/2017 Patient & Johnson Assistance Johnso & Product n Johnson Donation Patien Plaza t Kilmer Assist Square, ance Suite Founda 130 New tion Brunswi ck, NJ 08933 ------------------------------------------------------------------------ Product Partner 1616 $1,018,932 3/31/2017 Product ship Fort Donation for Myer for New Supply Drive, Horizons Chain 12th global Manage Floor public ment Arlingt health on, VA program 22209- 3100 ------------------------------------------------------------------------ Product Partner 1616 $124,669 9/8/2017 Product ship Fort donation for Myer for New Supply Drive, Horizons Chain 12th Global Manage Floor Public ment Arlingt Health on, VA Program 22209- 3100 ------------------------------------------------------------------------ Product US 1300 $302,250,000 12/18/2017 Product Agency Pennsyl donation for vania for global Intern Avenue, public ationa N.W. health l Washing programs Develo ton, DC pment 20523 ------------------------------------------------------------------------ Actelion Pharmaceuticals US, Inc. Contribution Payments Made in 2018 ------------------------------------------------------------------------ Organization Information Project Title Paid Amount Paid ------------------------------------------------------------------------ Westchester Medical Girls' Night Out $2,000.00 20180326 Center Foundation ------------------------------------------------------------------------ Scleroderma Research CONQUER Registry $500,000.00 20180125 Foundation Project ------------------------------------------------------------------------ Multiple Sclerosis The Latest MS $12,000.00 20180424 Association of America Research Updates ------------------------------------------------------------------------ Have a Ball Foundation 14th Annual ``Have a $5,000.00 20180309 Ball'' Golf Tournament ------------------------------------------------------------------------ CMDAT Research Foundation Free seminars on $1,400.00 20180411 pulmonary arterial hypertension and Gaucher disease in the Greater Denver area ------------------------------------------------------------------------ Echo Hill Outdoor School Echo Hill Outdoor $5,000.00 20180410 Heart Camp 2018 School Heart Camp 2018 ------------------------------------------------------------------------ Pulmonary Hypertension Chicago Area Trivia $3,200.00 20180510 Association Night ------------------------------------------------------------------------ American Lung Association St. Louis Lung Force $1,500.00 20180524 in Missouri Expo ------------------------------------------------------------------------ Pulmonary Hypertension Thirsting for a Cure $6,000.00 20180725 Association ------------------------------------------------------------------------ UPHill Journeys 11th Annual Northern $2,000.00 20180710 New England PH Forum ------------------------------------------------------------------------ Pulmonary Hypertension Steps for Stripes Fun $1,500.00 20180925 Association Walk ------------------------------------------------------------------------ American Heart Ann Arbor-Jackson $5,000.00 20181025 Association Heart Ball ------------------------------------------------------------------------ phaware global PHAWARE CHARITY $2,500.00 20181116 association POKER TOURNAMENT ------------------------------------------------------------------------ Pulmonary Hypertension Georgia Fun Walk $2,500.00 20181010 Association ------------------------------------------------------------------------ American Lung Association St. Louis Lung Force $1,500.00 20181010 in Missouri Expo ------------------------------------------------------------------------ Actelion has also made financial donations to independent charitable foundations that assist patients who are underinsured and in financial need with treatment-related expenses. In keeping with our donor agreements and applicable regulatory guidance, we will only disclose aggregate data on our charitable giving and do not publicize information on donations to specific foundations and disease states. In 2018, we contributed approximately $50.2 million in donations to independent charitable foundations, enabling them to provide assistance with medication-related copays to patients with pulmonary hypertension. ______ Submitted by Hon. John Thune, a U.S. Senator From South Dakota 340B Health 1101 15th Street NW, Suite 910 Washington, DC 20005 Phone: 202-552-5850 FAX: 202-552-5868 www.340bhealth.org 340B is a Small Share of the Drug Market and Does Not Increase Drug Prices New data show drug manufacturers provided $6.1 billion in total drug discounts in 2015 under the 340B Program. The 340B discount is less than 2 percent of the total U.S. drug market and is dwarfed by other segments of the drug industry. 340B does not increase drug prices. 340B reduces costs for safety net providers, allowing them to provide affordable drugs and services to low-income patients. [GRAPHIC(S) NOT AVAILABLE IN TIFF FORMAT] Compared to other segments of the market, the total 340B discount is: Less than 2 percent of total U.S. drug spending. 3.6 percent of all discounts and rebates offered by manufacturers. 4 percent of the specialty drug spending. 89 percent less than the rebates manufacturers provide to health plans and PBMs. 78 percent less than what manufacturers spend on advertising. 57 percent less than what brand-name manufacturers have lost from patent expirations. Nearly one third of the total 340B discount is due a penalty enforced against drug manufacturers for raising the price of drugs higher than the rate of inflation or voluntarily providing a discount lower than the 340B price. Manufacturers could avoid this penalty by not increasing their drug prices at such high rates. Total 340B Discount, $6.1 Billion ------------------------------------------------------------------------ ------------------------------------------------------------------------ Required by 340B Statute, $4.2 Billion Inflationary Penalty, $1.9 Billion ------------------------------------------------------------------------ The full analysis by Dobson Davanzo is available here: http:// www.340bhealth.org/files/340B_Financial_Impact_7_17.pdf. ______ Prepared Statement of Hon. Ron Wyden, a U.S. Senator From Oregon Prescription drugs did not become outrageously expensive by accident. It's not the result of a system too complicated for Americans to comprehend. Drug prices are astronomically high because that's where pharmaceutical companies and their investors want them. The brakes have come off pharmaceutical pricing, and American families are hurtling along in the passenger seat terrified of what comes next. Today the committee will hear uplifting stories about miracle cures, but it is morally repugnant when patients can't afford them. It is morally repugnant when ailing patients are forced to choose between filling that next prescription or putting food on the table, because they can't afford both. It is morally repugnant when patients are forced to skip doses. You Pharma executives are here because the way you do business is unacceptable and unsustainable. Ten companies accounted for half of all profts in the health-care sector last fall. Nine of those ten were drug manufacturers. All but one of today's witnesses represent companies on that list. Drug makers behave as if patients and taxpayers are unlocked ATMs full of cash to be extracted, and their shareholders are the customers they value above all else. Let's look at concrete examples, starting with AbbVie. AbbVie manufactures the top-selling prescription drug in America, the arthritis medication Humira. Over 6 years, the company doubled the price of a 12-month supply from $19,000 to $38,000. Can patients opt for a less-expensive alternative? No they cannot, because AbbVie protects the exclusivity of Humira like Gollum with his ring: thick cobwebs of patents, legal tricks, and shadowy deals with other drug makers, all to keep the cash flowing. I also want to address troubling information the committee recently uncovered. I'm holding AbbVie's proxy statement, a document every publicly traded company must file with the SEC. Page 37 shows that in 2017, a portion of CEO Richard Gonzalez's multi-million-dollar bonus was directly tied to sales of Humira. It appears the same incentive was in place in 2015 and 2016. In fact, the committee's review shows that all of AbbVie's top executives had the same arrangement. Mr. Gonzalez is welcome to respond, but the implication of that incentive ought to be clear. From top down, AbbVie's leadership had reason to keep pushing prices and sales upward. Now on to Pfizer. Pfizer gets first prize for emptiest gesture on pricing in 2018. After stern Trump tweets last year, Pfizer said it would temporarily freeze prices. But once the President got his splashy headlines, his gaze turned elsewhere, and Pfizer's former CEO told investors it was back to ``business as normal.'' Another round of price hikes in 2019, including on its pain medication Lyrica. Lyrica's price has increased 163 percent since 2012. With this one drug, Pfizer raked in $4.5 billion in 2017. Merck: Merck gets second prize for emptiest gesture on pricing in 2018. It made sweet-sounding promises after coming under criticism, but it cut prices for drugs that provide essentially no revenue to the company. Left untouched were the cash cows Keytruda and Januvia, which account for more than a quarter of Merck's revenue. It's like promising car shoppers a great deal, except the only discounted model on the lot is an Edsel. Sanofi: A company wringing more and more cash out of people with an incurable disease. In 2010, a vial of Sanofi insulin cost less than $100. In 2018 it cost nearly $300, and the company raised prices again in 2019. Considering that the landmark breakthrough on insulin came early in the roaring twenties, nothing could justify that sudden price increase nearly a century later. Diabetics who can't afford the costs are self-rationing and endangering their lives, but at least the investors are happy. AstraZeneca: A lesson in saying the quiet part out loud. In an interview earlier this year, CEO Pascal Soriot complained that his $12- million salary made him ``the lowest-paid CEO in the whole industry.'' He said it was ``annoying to some extent.'' His company, meanwhile, continues to raise the price of Symbicort, its $3-billion asthma drug. For some asthmatics, being able to breathe costs hundreds of dollars a month. Johnson & Johnson: A record-setting flip-flop. This January 7th, at the JP Morgan Healthcare Conference, CEO Alex Gorsky said that the pharmaceutical industry needed to self-police on pricing. Sounds good, but it didn't last long. Three days later, his company hiked the prices of hundreds of its drugs, including drugs that account for billions in Medicare spending. Bristol-Myers-Squibb: In 2017, the company spent roughly $11.5 billion on dividends, stock buybacks, marketing, sales, and administrative costs. That's roughly triple the amount it spent on R&D. This is all a stark illustration of drug makers' profiteering and two-faced scheming. The central argument that the committee will hear in response is that the fault is everybody else's. The health plans are at fault. The PBMs are at fault. Regulators are at fault. They always point the finger elsewhere. We'll also hear that list prices don't matter; that the true costs are complicated. But companies don't set and raise list prices for fun. Those prices are directly tied to the amount patients pay out-of-pocket at the pharmacy window. They are directly tied to what taxpayers spend on health-care programs. Next, drug makers point fingers at the middlemen, pharmacy benefit managers. I've said for years that PBMs are wasteful and secretive, taking their cut without proving their worth to anybody. They will have their day before this committee. But PBMs don't set list prices; manufacturers do. Furthermore, manufacturers don't offer rebates for nearly 40 percent of Part D brand-name drugs. Those prices continue to rise. That's on the drug companies, not on PBMs. Next, drug makers say changes in the status quo will hurt R&D. A quick look at these companies' finances, on both sides of the balance sheet, shows that isn't the case. Revenue generated from American patients alone dwarfs what they spend on R&D worldwide. Drug makers also spend as much, if not more, on flashy TV ads and office-to-office salesmen as they spend on R&D. And if lower prices would diminish R&D, why don't costly dividends? Why don't stock buybacks? Is the stock price more important than inventing the next miracle cure? Even if you buy the specious argument that a drug's list price at launch is driven by the cost of R&D, what could justify arbitrary price increases year after year, long after the R&D spending is done? Finally, companies say they help patients afford drugs with ``coupons`` or patient assistance programs. But if these programs are so widely generous, why can't drug makers instead simply lower prices across the board? Because it's just more slick branding--ploys that allow companies to maintain the status quo. One final point. I was there when seven Big Tobacco CEOs testifed in a committee room like this one, and they lied. The chairman and I expect better this morning. Your profits are outsized compared to others in the industry, you receive a massive portion of your revenue from American taxpayers, and you bear none of the consequences of high drug prices. It's past time to get beyond the excuses and make prescription drugs affordable. ______ Communications ---------- AARP 601 E Street, NW Washington, DC 20049 202-434--2277 | 1-888-OUR-AARP | 1-888-687-2277 | TTY: 1-877-434-7598 www.aarp.org | twitter: @aarp | facebook.com/aarp | youtube.com/aarp February 26, 2019 The Honorable Chuck Grassley The Honorable Ron Wyden Chairman Ranking Member Committee on Finance Committee on Finance U.S. Senate U.S. Senate 219 Dirksen Senate Office Building 219 Dirksen Senate Office Building Washington, DC 20510 Washington, DC 20510 Dear Chairman Grassley and Ranking Member Wyden: AARP appreciates your focus on prescription drug prices and the challenges that increasing drug costs pose for seniors, and we thank you for holding the hearing on February 26, 2019, to highlight rising prescription drug prices. AARP, with its nearly 38 million members in all 50 states, the District of Columbia, and the U.S. territories is a nonpartisan, nonprofit, nationwide organization that helps people turn their goals and dreams into real possibilities, strengthens communities and fights for the issues that matter most to families such as healthcare, employment and income security, retirement planning, affordable utilities and protection from financial abuse. Prescription drug prices are a high priority for AARP and all older Americans, as older adults are particularly vulnerable to high prescription drug prices. Medicare Part D enrollees take an average of 4.5 prescriptions per month, and over two-thirds have two or more concurrent chronic illnesses. When older Americans talk about the impact of high prescription drug prices, they are often talking about costs that they will face every year for the rest of their lives. Most Medicare beneficiaries live on modest incomes, with an annual median of just over $26,000. One-quarter have incomes of just over $15,000. One-quarter have less than $15,000 in savings. This is not a population that has the resources to absorb rapidly escalating prescription drug prices, and many are simply unable to afford the medications they need. Unfortunately, older Americans have seen their prescription drug prices skyrocket in recent years. About 30 years ago, the public was outraged over a drug that cost less than $10,000 per year. We now have drugs with prices approaching $1 million per year. In 2015, the average annual cost for a single specialty drug used on a chronic basis was $52,486--which is only slightly less than the median household income in the United States.\1\ We strongly support efforts to bring new treatments to market, but innovation is meaningless if patients cannot afford to use the treatment. --------------------------------------------------------------------------- \1\ https://www.aarp.org/content/dam/aarp/ppi/2017/11/full-report- trends-in-retail-prices-of-specialty-prescription-druqs-widely-used-by- older-americans.pdf. AARP has been tracking the prices of widely-used prescription drugs since 2004. Our most recent Rx Price Watch Report focused on brand-name drugs and found that their retail prices increased by an average of 8.4% in 2017--four times the rate of inflation. AARP's report also examined how drug companies' relentless price increases add up over time and found that the average annual cost of one brand-name drug--now around $6,800--would have been just under $2,200 in 2017 if retail price changes had been limited to general inflation between 2006 and 2017.\2\ --------------------------------------------------------------------------- \2\ https://www.aarp.org/content/dam/aarp/ppi/2018/09/trends-in- retail-prices-of-brand-name-prescription-druqs-year-end-update.pdf The average annual price increases for brand name drugs have exceeded the corresponding rate of inflation every year since at least 2006. More importantly, this problem goes beyond a few bad actors: virtually --------------------------------------------------------------------------- all of the manufacturers we track raise their prices every single year. As a result, it is hardly surprising that our members consistently tell us they cannot afford the medications they need and are forced to make difficult choices as a result. Even less surprising is that they want this situation to change. Last year, in AARP's 2018 Mid-Term Voter Issues Survey, 92 percent of voters age 50 and older told us that candidates' positions on lowering drug costs was important to them, with 74 percent saying ``very important.'' Moreover, in a Kaiser 2018 Health Tracking Poll, prescription drug prices topped the list of the public's priorities, with 90 percent calling it an important priority, and 52 percent listing it as a ``top priority.'' In that poll, a large majority (80 percent) of the public reported perceiving prescription drug costs as ``unreasonable,'' a share that has increased since 2015. Today it seems that prescription prices are in a never-ending race to the top. High priced specialty drug approvals have exceeded traditional drug approvals since 2010, and the number of people using such drugs is growing. Meanwhile, the research pipeline is full of products like orphan drugs, biologics, and personalized medicines that face little competition and will undoubtedly command even higher prices. We have also seen massive increases in Medicare spending on prescription drugs. Between 2005 and 2016, Medicare Part B drug spending more than doubled from $12 billion to $29 billion. Total Medicare Part D spending is approaching $150 billion. These escalating costs will eventually result in higher taxes, cuts to vitally important public programs, or both. Current prescription drug price trends are simply not sustainable. High and growing drug prices are affecting all Americans in some way. Their cost is passed along to everyone with health coverage through increased health care premiums, deductibles, and other forms of cost-sharing. They are also driving larger cost increases for a variety of taxpayer- funded programs. Meanwhile, drug companies are working very hard to try to shift the blame to others in the health care system, leaving them free to set incredibly high prices and increase them with little restraint. It is long past time for Congress to take action to rein in high drug prices. Thoughtful bipartisan efforts to help reduce prescription drug prices could save tens of billions of dollars for patients, taxpayers and the U.S. health care system. More importantly, they will help ensure that all Americans have affordable access to the drugs that they need to get and stay healthy. We look forward to working with this Committee to find solutions that will lower prescription drug prices and costs for older Americans. If you have any additional questions, feel free to contact me or have your staff contact Amy Kelbick on our Government Affairs staff at [email protected] or 202-434-2648. Sincerely, Joyce A. Rogers Senior Vice President Government Affairs ______ American Society of Health-System Pharmacists (ASHP) 4500 East West Highway, Suite 900 Bethesda, MD 20814 Email: [email protected] Phone: 301-664-8692 ASHP (American Society of Health-System Pharmacists) respectfully submits the following statement for the record to the Senate Committee on Finance hearing on ``Drug Pricing in America: A Prescription for Change, Part II.'' ASHP represents pharmacists who serve as patient care providers in acute and ambulatory settings. The organization's nearly 50,000 members include pharmacists, student pharmacists, and pharmacy technicians. For more than 75 years, ASHP has been at the forefront of efforts to improve medication use and enhance patient safety. ASHP's vision is that medication use will be optimal, safe, and effective for all people all of the time. A primary tenet of that vision includes access to affordable medications needed to save or sustain lives. Addressing the issue of skyrocketing drug prices, including excessive price increases on commonly used generic medications, is one of ASHP's highest and longstanding public policy priorities. According to a Kaiser Health Tracking Poll, 1 in 4 Americans cannot afford their medications.\1\ Poor access to medications can lead to increased morbidity and mortality, and can cause healthcare costs to increase. --------------------------------------------------------------------------- \1\ DiJulio, Bianca, et al. ``Kaiser Health Tracking Poll: August 2015.'' The Henry J. Kaiser Family Foundation, 20 Aug. 2015, www.kff.org/health-costs/poll-finding/kaiser-health-tracking-poll- august-2015/. Accessed February 10, 2019. ASHP has been proactively addressing challenges related to the rapid increase of prescription drug pricing on several fronts, including working with like-minded stakeholders and educating members of Congress about the unsustainable burdens faced by patients, healthcare --------------------------------------------------------------------------- providers, and the entire healthcare system. ASHP is a lead member of the Steering Committee of the Campaign for Sustainable Rx Pricing (CSRxP), a coalition of prominent national organizations representing physicians, consumers, payers, hospitals, health systems, and patient advocacy groups. CSRxP has developed a policy platform promoting market based solutions supported by three pillars: competition, value, and transparency. The goal of the campaign is to identify policy options that have bipartisan support and, therefore, a greater likelihood of passage. To that end, CSRxP focuses on policies to incentivize a more competitive marketplace to help stimulate lower drug prices. The campaign has also expressed support for efforts to loosen restrictions that prevent generic drug companies from obtaining the samples necessary to manufacture a competing product. The price increases have placed enormous budgetary pressure on healthcare organizations, including hospitals and health systems. ASHP, along with the American Hospital Association (AHA) and the Federation of American Hospitals (FAH), recently released a report on the impact that the cost of and access to prescription drugs are having on hospital budgets and operations. Specifically, the report showed that: Average total drug spending per hospital admission increased by 18.5% between fiscal years (FY) 2015 and FY2017. Outpatient drug spending per admission increased by 28.7%, while inpatient drug spending per admission increased by 9.6%, between FY2015 and FY2017. Hospitals experienced price increases of over 80% across different classes of drugs, including those for anesthetics, parenteral solutions, and chemotherapy. Over 90% of surveyed hospitals reported having to identify alternative therapies to manage spending. One in 4 hospitals had to cut staff to mitigate budget pressures.\2\ --------------------------------------------------------------------------- \2\ NORC at the University of Chicago. ``Recent Trends in Hospital Drug Spending and Manufacturer Shortages'' (2019), https://www.aha.org/ system/files/2019-01/aha-drug-pricing-study-report-01152019_1.pdf. Accessed 25 Feb. 2019. ASHP does not collect, store, or report drug pricing information. However, we continually hear from pharmacy leaders in hospitals and health systems that sudden, inexplicable, and unpredictable price increases in connection with some of the most commonly used, long standing generic medications are becoming more prevalent--and are --------------------------------------------------------------------------- occurring on a nationwide basis. As there is no single solution to spikes in the prices of certain drugs, there is no single cause either. In this statement, we address four additional issues as they relate to drug pricing: competition, Risk Evaluation and Mitigation Strategies (REMS), Direct and Indirect Remuneration (DIR Fees), and the 340B Drug Pricing Program. COMPETITION In particular, ASHP would like to learn more about the marketplace dynamics that could contribute to this issue, as we have worked diligently to address the issue of drug shortages for nearly 15 years. Although drug shortages are caused by a number of factors, we have observed that drugs in short supply made by only one or two manufacturers often result in higher-than-normal prices. If, for example, there is a lack of competition in the generic market place, we urge the committee to look at ways to stimulate more marketplace presence. ASHP supports bills such as S. 64, the ``Preserve Access to Affordable Generics and Biosimilars Act.'' This bipartisan bill would potentially increase competition by prohibiting companies from engaging in ``pay-to-delay'' tactics to stifle generic and biosimilar entry into the market. RISK EVALUATION AND MITIGATION STRATEGY (REMS) ASHP recognizes that there may be limited circumstances in which constraints on the traditional drug supply system may be appropriate for reasons of patient safety, including through the use of manufacturer-driven REMS. However, we believe that REMS should never be used to artificially inflate drug prices, nor should REMS interfere with the professional practice of pharmacists, physicians, nurses, and other providers. We believe that there may be current cases in which a manufacturer- driven REMS using restricted distribution is causing higher prices for those drugs, having adverse effects on patient access, and delaying treatment. In some cases, there may be evidence to suggest that the use of restricted or limited distribution channels has resulted in the inability of a potential competitor to acquire enough of a drug to conduct the required testing to bring a generic competitor to market. For this reason, ASHP thanks Chairman Grassley for introducing S. 340, the ``Creating and Restoring Equal Access to Equivalent Samples (CREATES) Act of 2019.'' The CREATES Act will help ensure that brand- name pharmaceutical companies cannot manipulate regulatory rules to prevent competition, which is essential for patient access to affordable medications. Additionally, we recommend that Congress require the Food and Drug Administration (FDA) to investigate restricted distribution under a REMS as a means to artificially increase drug prices and limit access to critical medications. Restricting distribution of medications is often a means to push patients to a specific purchasing channel, which in some cases increases not only their out-of-pocket costs, but also systemic costs. Further, restricted distribution networks can complicate patient access to critical medications, potentially disrupting care. DIRECT AND INDIRECT REMUNERATION FEES (DIR FEES) Many factors contribute to high drug product costs; addressing the problem is made difficult by lack of transparency about the marketplace for those products. For example, DIR fees and other rebates negotiated by pharmacy benefit managers (PBMs) make it difficult to determine the actual cost of a drug. DIR fees are a growing nationwide concern among pharmacies that dispense medications in a community pharmacy or outpatient clinic setting. Created under the Medicare Part D Program, DIR fees were originally intended as a way for CMS to account for the true cost of the drug dispensed, including any manufacturer rebates. Often these rebates were unknown until the drug was dispensed and the claim adjudicated. Moreover, the fees themselves, which are often arbitrary in nature, have mushroomed over the past decade, to the point that pharmacies regularly see annual DIR totals in the tens of thousands of dollars. Recently, a concerning trend has emerged in which pharmacy benefit managers (PBMs) have begun to charge DIR fees to their pharmacy providers. Under this scenario, PBMs are inappropriately applying their own plan performance measures as a way to assess fees on pharmacies. This is problematic for the following reasons: It is an arbitrary and unintended application of quality measures meant for total plan performance as opposed to pharmacy-level metrics. The quality measures applied tend to be based on maintenance medications such as blood pressure medications or medications used to treat diabetes. These measures were never intended to be applied to specialty medications or to other specialized disease states such as oncology, yet PBMs assess DIR fees against the gross reimbursement for all prescriptions received by pharmacy providers, not just maintenance medication s. Pharmacy providers are essentially being penalized with backdoor fees without any requirement that PBMs define, justify, or explain these charges to providers and to CMS. DIR fees assessed on pharmacies providing specialty medications have been especially hard-hit, due to the fee structure. Fees could be a flat rate of per dollar per claim or a percentage (typically 3-9%) of the total reimbursement per claim. Using the percentage-based structure, the fees would increase markedly for specialty drugs, which are typically much more expensive than maintenance medications, sometimes resulting in thousands of dollars. A 9% fee on a drug costing $100,000 is $9,000. Additionally, these fees are assessed retroactively, sometimes months after the claim has been adjudicated, providing no recourse for the pharmacy impacted by the assessment. The result of imposing DIR fees has led to higher cost-sharing responsibilities for Medicare beneficiaries, which have, in turn, caused more of these beneficiaries to enter the Part D donut hole, where the patient is solely responsible for the cost of the drug. Along with the higher costs absorbed by patients, adherence rates tend to be lower among Medicare beneficiaries who are in the donut hole and may not have the financial resources to pay for their medications. This is in stark contrast to the very reason DIR fees targeting manufacturer rebates were created--so that savings could be passed on to patients. Pharmacies are not alone in their concern. In January 2017, CMS published a fact sheet expressing concern over DIR fees and cited those fees as contributing to increased drug costs, which, in turn, increased patients' out-of-pocket spending and Medicare spending overall.\3\ Additionally, questions remain as to whether Part D plan sponsors have the authority to assess these fees on pharmacies. There are no references to DIR fees collected on pharmacies in either the Part D statute or corresponding CMS regulations. --------------------------------------------------------------------------- \3\ Fact sheet, ``Medicare Part D--Direct and Indirect Remuneration (DIR).'' Centers for Medicare and Medicaid Services, 19 January. 2017, https://www.cms.gov/newsroom/fact-sheets/medicare-part-d-direct-and- indirect-remuneration-dir. Accessed February 10, 2019 --------------------------------------------------------------------------- ASHP's professional policy on DIR fees is as follows: To advocate that payers and pharmacy benefit managers be prohibited from recovering direct and indirect remuneration fees from pharmacies on adjudicated dispensing claims; further, To oppose the application of plan-level quality measures on specific providers, such as participating pharmacies.\4\ --------------------------------------------------------------------------- \4\ ASHP Policy 1814, ``Direct and Indirect Remuneration Fees.'' --------------------------------------------------------------------------- THE 340B DRUG PRICING PROGRAM For 25 years, the federal 340B program has allowed safety-net hospitals ``to stretch scarce Federal resources as far as possible, reaching more eligible patients and providing more comprehensive services.'' This program has been essential to expanding access to lifesaving prescription drugs and comprehensive healthcare services to low-income and uninsured individuals, at no cost to the federal government. The federal 340B program is not causing high drug prices. The program accounts for less than 5% of annual drug purchases in the United States, while safety-net providers give 30% of the care. There are many contributing factors to higher drug costs, but there is no objective evidence that the program has increased overall drug pricing. In fact, the 340B program is revenue-neutral, benefiting patients without increasing costs for federal payors. The federal 340B program enables these hospitals to serve their communities by providing vital care such as: Free or lower-cost medications to patients. Programs to increase medication adherence, including clinical pharmacy services to high-risk patients who are on multiple and/or complex medications. Increased access to primary care. Screenings and preventive care services to detect health problems early and decrease morbidity and mortality, as well as to decrease healthcare costs and hospital admissions. The federal 340B program is at risk because of a recent change in Medicare payment policy that reduces payment from average sales price plus 6 percent to average sales price minus 22.5 percent. Cuts of this magnitude undermine the intent of the program, reducing resources that hospitals use to expand access to care and services to vulnerable communities. Given the increasingly high cost of pharmaceuticals, the federal 340B program provides critical support to the entities eligible to participate in the program. CONCLUSION ASHP thanks the Committee on Finance for holding this important hearing. ASHP remains committed to working with Congress and industry stakeholders to ensure that patients have affordable access to lifesaving and life-sustaining medications. ______ Coalition for Affordable Prescription Drugs U.S. Senate Committee on Finance Dirksen Senate Office Bldg. Washington, DC 20510-6200 Tuesday, February 26, 2019 The Coalition for Affordable Prescription Drugs (CAPD) appreciates the opportunity to submit the following statement for the record. Overview CAPD is a diverse group of employers, unions, public sector employees and retirees and the pharmacy benefit managers (PBMs) they partner with to provide more affordable prescription drug coverage for millions of Americans. Today, too many patients and families are struggling to pay for the medications they need. It's no surprise that a recent Politico/Harvard Chan School of Public Health poll showed that 80 percent of Americans see high prescription drug prices as a top priority for the new Congress and the Administration. The Role of PBMs in Lowering Costs In the face of rising drug prices, PBMs partner with employers, unions, public sector retirees and other organizations who purchase health care to help manage prescription drug coverage for millions of Americans. By negotiating with drug companies and providing patient-centered tools to improve care and help lower out-of-pocket costs, PBMs save over $900 per person each year. In addition, PBMs are expanding visibility into drug prices by enabling doctors and patients to see the price of various medicines at the point of prescribing, based on the individual's specific drug benefits. With this information, physicians switch to a more affordable medicine nearly 20 percent of the time when clinically equivalent alternatives are offered through UnitedHealth Group's RTBT, PreCheck MyScript. In another example, CVS Health's Real Time Benefits tool has saved patients an average of $120 to $130 per fill. Drug Company Prices Are the Problem Although there have been many ideas proffered about how to address the rising prices of medicines, CAPD believes that we first need to address the root problem: prices set by drug makers. Drug companies alone set their prices and they are rising at an unsustainable rate. In fact, drug companies have raised prices already in 2019 on hundreds of medicines. And, what's worse is that this is repeat behavior. Drug companies often raise those prices multiple times a year for the exact same product. Over the last five years, prices increased on the top 20 most prescribed brand-name drugs for seniors by an average of 12 percent each year, which is significantly above the annual rate of inflation. The truth is simple: Drug companies hike their prices because they can. When they do so, millions of patients pay more at the counter. Drug companies, hoping to avoid scrutiny and sustain high profits, are pointing the finger at every other industry except themselves. According to drug companies, the reason why drug prices are so high isn't because they keep raising prices, or abuse the patent system, or make by far the highest profits in health care--it's everyone else's problem, not theirs. In today's testimony, we will likely hear a common refrain from drug companies: part of the reason that drug prices are so high are because of the rebates that they are forced to give to PBMs. But the problem with this argument is that, according to a recent study, there is little correlation between prices drug companies set for their drugs and the rebates negotiated by PBMs across 23 major drug categories. What's more, in Medicare Part D, even after accounting for rebates, the costs of brand name drugs still increased 62% from 2011 to 2015. All parties need to come to the table to make prescriptions more affordable and accessible to the patients who need them--but nothing will be done if pharma refuses to even pull up a chair and address the problem where it starts: their high prices. We hope Congress will use this hearing as an opportunity to ask the pharmaceutical industry to answer for these increases. Pharma's Gamesmanship Reducing Competition to Keep Prices High One way to meaningfully lower drug prices for patients is to stop the gamesmanship of the patent and regulatory systems that drug companies use to maintain their monopoly pricing power and keep lower-cost generic alternatives from entering the market. Brand drug manufacturers exploit the FDA Risk Evaluation and Mitigation Strategies (REMS) program to prevent generic drug makers from accessing needed samples, costing the U.S. health care system $5.4B each year. The CREATES Act, which passed out of the Senate Judiciary Committee last year, is a targeted, market-based, bipartisan solution to the longstanding problem of brand name pharmaceutical companies denying generic manufacturers access to the samples they require to conduct necessary equivalence testing to bring their product to market. Another way brand drug manufacturers game the patent and regulatory system is through ``pay-for-delay'' deals, in which drug makers engage in anticompetitive patent settlements with potential generic competitors, resulting in $3.58 in higher drug costs each year. In the most high-profile example of these abuses, drug maker AbbVie last year reached agreements with Amgen, Samsung Bioepis and Mylan to delay entry of a lower-cost biosimilar version of the drug to 2023 in the United States. A third example of gamesmanship by brand drug manufacturers is evergreening, in which generic competition is delayed by additional patents on minor variations of the original drug for the clear purpose of extending monopoly protection. While these tweaks often do not convey enhanced clinical benefits to the patient, they do extend the time period during which drug manufacturers can continue to control pricing by preventing competition. For example, best selling drug Humira to treat rheumatoid arthritis and psoriasis is protected by over 100 patents and the product may not face any competition until as late as 2034. We encourage Congress to explore proposals that target patent and regulatory abuses by drug companies in order to lower drug prices for patients. Conclusion Simply put, a patient cannot be helped by a drug they cannot afford. We ask today that Congress once and for all refuse to accept drug manufacturers' excuses for high prices and take steps to put an end to the patent and regulatory abuses that keep prices artificially high. We believe the time to act is now. CAPD is committed to working with Congress and other stakeholders on this and other solutions to meaningfully lower prescription drug prices for all Americans. We look forward to supporting this critical effort. Debra Barrett Executive Director, Coalition for Affordable Prescription Drugs Contact: Meghan Scott Spokesperson, Coalition for Affordable Prescription Drugs [email protected] (202) 341-2060 What They're Saying: Don't Let Pharma Off the Hook On January 29, the Senate Finance Committee held a hearing, ``Drug Pricing in America: A Prescription for Change.'' During the hearing, both Senators and witnesses discussed drug companies' high prices and their anti-competitive actions. DRUG COMPANIES' HIGH PRICES Chairman Chuck Grassley (R-Iowa): ``I've also heard from seniors who have seen their prescriptions increase month after month for no apparent reason. And I've heard stories about people reducing their life-saving medicines...to save money. This is unacceptable. . . . But other drugs are creating problems as well, that is why tackling high prescription drug costs is one of Senator Wyden's and my first priority on this committee.'' Ranking Member Ron Wyden (D-Oregon): ``So there's no shortage of evidence about what the problems are. The companies have unchecked powers to set prices on their own, and often it's to meet Wall Street's expectations rather than meet demand in the market.'' Mark Miller, The Arnold Foundation: ``The revenues that come out of the United States exceed R&D by something like 70, 75 percent. . . . So the first point is when people say R&D is driving these prices, there is a big disconnect in there. . . . We found many companies in which they're spending much more on advertising, marketing and other administrative expenses than they are on R&D.'' Peter Bach, Memorial Sloan Kettering: ``Prices for monopoly goods such as these are determined by the market in which they are sold, not the other way around. . . . Please realize that these drugs do not inherently cost $1 million any more than they inherently cost $1.'' Kathy Sego, mother of a child with diabetes: ``As a mother, I would probably say to them--I hope you know that there are people who are going without their medication, and because they're going without their medication they're at risk of dying. And how can you be OK with that? . . . That should never be a decision that a person needs to make. And unfortunately, it is.'' GAMESMANSHIP AND ANTICOMPETITIVE PRACTICES Douglas Holtz-Eakin, American Action Forum: ``We have some very isolated instances of cost associated with off-patent sole-source drugs. And in those circumstances, it appears that firms are able to take advantage of their market power and raise the prices of drugs sharply. This strikes me as a fundamental anti-competitive act that ought to be investigated.'' Senator Robert Menendez (D-New Jersey): ``Manufacturer coupons, many suggest, distort spending. . . . Who's winning with these coupons?'' Peter Bach: ``I can assure you we know who's winning and it's the people who are printing the coupons . . . the reality is they're artificial price supports.'' Senator Maggie Hassan (D-New Hampshire): ``We've seen a lot of bad actors gaming the system over the years, really to pad their pockets. There are countless ways drug companies take advantage of loopholes and taxpayers end up footing the bill.'' Mark Miller: ``We need to curb the anticompetitive behaviors of manufacturers and inject competition back into the marketplace. Manufacturers benefit from taxpayer-funded NIH research and from government granted monopolies. And naturally, they devote resources to protecting those monopolies.'' AffordablePrescriptionDrugs.org ______ Letter Submitted by Linda George March 4, 2019 U.S. Senate Committee on Finance Dirksen Senate Office Bldg. Washington, DC 20510-6200 RE: ``Drug Pricing in America,'' Senate hearing held on February 26, 2019 Dear Finance Committee: On Wednesday January 23, 2019, I gave myself my last weekly injection of Humira, which had helped my mobility due to psoriatic arthritis. I have done very well for the past two years with this drug--one typically requiring a biweekly 40mg syringe injection. But I just started a new medication, an infusion administered in my doctor's office by an outsourced nurse who's not part of the practice. I needed to switch to the infused medication because on March 1st-- when I became eligible for Medicare--Humira would increase from $5/ monthly under our previous private insurer, Anthem Blue Cross, to a prohibitive $800+ per injection with Medicare Part D coverage. Bottom line: Medicare does not cover self-injections. Because an infusion would be administered in my rheumatologist's office, it is 100% covered as a medical procedure through Part B via Medicare. Now, I understand why Humira's advertisements, invading my television screen no matter what time or what channel I watch, always feature younger people engaged in various physical activities. When I needed information about how to navigate this insurance morass, I called my Humira ambassador, an AbbVie employee who serves as a liaison between the consumer and the company. She assured me that I may be covered if I submitted my tax returns to the company's foundation. Evidently if I make less than $65,000, through the company's assistance program, the parent company's foundation pays a portion of the thousands needed to offset consumers' exorbitant cost of this drug; however, regardless of my income, I have a huge problem submitting my tax statements to anyone--except to my trusted accountant and the IRS. It seems AbbVie puts some big money into tiers of bureaucracy through advertising, marketing, and supporting a foundation based on employees forced to donate a percentage of their income. In addition, whenever a consumer needs to have the simplest question answered by the company, instead of AbbVie offering an 800 phone number, that consumer must first enroll in the ``Ambassador Program,'' then wait for their designated ambassador to return the call. I've had two ambassadors so far, and each seems more than willing to keep me on the phone for an extended time, asking all kinds of questions, as if padding their own positions by calling consumers on a monthly basis. I'd much prefer that these ambassadors work to figure out ways to reduce the drug's cost, so consumers like me can afford it. Switching to new medication certainly had caused me some angst. I had no sense of how I will respond to the new infusion. Based on history, I've had my share of side effects during the 38 years I've been dealing with arthritis. I have trouble with drugs that are ingested through the GI tract. I also have had two different cancers, a risk accompanying many of the biologic arthritis medications. In addition, I've had some serious adverse reactions to medications, requiring hospitalization. Lucky for me, the new infusion, 100% covered by Medicare Part B, seems to be working well. Despite having this ailment, I consider myself to be healthy, doing whatever possible to maintain whatever I can do to stay well to overcome arthritis' swelling, fatigue, and pain that has challenged me physically and mentally. I probably have had more knee aspirations and steroid injections than some Olympic athletes. My Fitbit gets a daily workout. Even after trying many alternative treatments in search of a solution, Humira seemed to help me resume a normal life. And for that, I was grateful. AbbVie Chairman and CEO Richard A Gonzalez stated at the U.S. Senate Finance Committee on February 26, 2019, ``We believe it is important that discussions about access and affordability include a focus on how to alleviate Medicare Part D out-of-pocket burdens above and beyond just lowering list prices.'' I must raise the question to AbbVie: What is the company doing internally to cut costs for consumers? I am hoping that you will help address the mounting bureaucratic issues surrounding health care in America that make it challenging for consumers to afford and navigate. Please feel free to reach out to me if you need more information or assistance in any way. Yours, Linda George cc: Senator Patrick Toomey Senator Bob Casey Attorney General Josh Shapiro ______ Statement of Robin K. Huszagh February 26, 2019 After listening to the hearing today on C-SPAN, I wanted to share my situation with you as a patient being forced to pay the full ``negotiated'' price for Humira and Enbrel. My husband and I are self- employed and self-insured. We must purchase health insurance through the independent ``retail'' market. I specifically renewed a grandfathered ``retail'' PPO health insurance policy we've had since 2010 for our family of 3, now priced at $2,166.00/month, so that could get the specialty formulary I needed to treat my Rheumatoid Arthritis at an affordable price and continue to see my doctors. To my distress, the Insurer (BCBS) and Pharmacy Benefit Manager (Prime Therapeutics) altered the PPO plan's pharmacy benefits (cost sharing details) after the plan commenced, leaving me with an expensive policy that no longer covers my expensive specialty formulary at an affordable price. Unlike typical commercial employer-based group policies, once I needed the expensive specialty formulary, my independent retail PPO policy was switched into a restricted pharmacy network with only one mail-order supplier and an ``Accumulator Adjustment Program.'' The Insurer/PBM also blocked the use of drug manufacturer's discount coupons and programs completely (worth $12,000 to $16,000 per year in my case) so that a drug that used to cost me $5.00 to $10.00 per month with a manufacturer's coupon now costs between $5356 to $6652 per month, the negotiated contract rate between the insurer and the drug manufacturer. My deductible was raised from $2600 to $5200 for a 20% coinsurance responsibility and $11,200 out-of-pocket max for full benefits. The insurer added a second review process in 2019 for any drug with a contract rate of $5000/month or higher, in addition to the one put in place in 2018 as part of a ``step therapy'' restriction/review. In 2019 the price for both Humira and Enbrel jumped to over $5000 per month and the insurer has stated their ``secondary review'' would allow them to deny benefits for these drugs even though the policy states they are approved formularies. At the current premium rate, paying for insurance and an expensive formulary has been financially challenging to say the least and has caused us to take an early withdrawal from our IRA. I contacted the Illinois Department of Insurance and asked why insurers can change pharmacy benefits mid-year and weren't required to document the specific cost-sharing and pharmacy details on all insurance policy documents, so benefits are locked in for the year. I was told those details are NOT a requirement for retail plans, and pharmacy benefit changes are allowed to occur throughout the life of the contract which also includes medication price changes. So, if a consumer buys a policy based on access and pricing for a particular drug, there is no guarantee the terms will remain in effect for the full contract year. I was never notified of the changes even after contacting the insurer. I hadn't realized any changes until I went to the pharmacy to pick up a prescription and hit the payment ``brick wall''! The Network Transparency Act of 2019 was passed in Illinois, however that only set policy guidelines for ``notification requirements'' to the policy holder if a particular provider pulls out of a network but doesn't address the insurer's ability to change a policy's pharmacy benefits mid-year, leaving the policy holder with a shocking bill. The contract price for Humira went up 9% in January, the cost of my PPO policy went up 9% in 2019, and now I'm required to pay a higher premium, higher out-of-pocket max, and the full price for Humira without the use of manufacturer's discount programs. Patients with employer-based group plans who are already benefiting from employer cost-sharing perks are allowed the use of discount programs and coupons at the point of sale (the pharmacy) because the insurer and the employer never know the coupon is being used as a form of payment at the retail pharmacy location. The coupon value pays for the drug and that hidden payment is applied to the user's deductible. Those who benefit from these programs do not care what the list price or the negotiated price is for a high-priced drug because they never have to actually pay it, the insurer pays for it because deductibles and out- of-pocket limits are met early in the year. Those with commercial group plans obtain specialty formularies for $5 to $10 per month. I have to pay the full price. The change in my PPO policy was intentionally made by the insurer to ensure I personally pay the full cost of the drug for as long as possible. They do not want me to get assistance from Pharma to reach my deductible or maximum. There is no relief in sight for the independently insured who have no employer or government subsidies and actually pay the full high price for each medication and monthly insurance premiums. With the majority of Americans getting health insurance perks from their employer and using drug coupons, there is no incentive for drug manufacturers to ever lower list prices. ______ Interfaith Center on Corporate Responsibility (ICCR) 475 Riverside Drive, Suite 1842 New York, NY 10115 (212) 870-2295 www.iccr.org March 12, 2019 Mr. Chairman, Ranking Member and Members of the Committee: ICCR is a coalition of over 300 global institutional investors representing more than $400 billion in managed assets. Leveraging our equity ownership in some of the world's largest and most powerful companies, ICCR members regularly engage management to identify and mitigate social and environmental risks resulting from corporate operations and policies. While ICCR members never shy away from making the moral case for action, our fundamental proposition as investors is that responsible and sustainable business practices--and a strong corporate culture of ethics--are in the long-term interest of companies, investors and communities. ICCR members have a long-standing history of engagement with pharmaceutical companies on issues of price restraint, equitable pricing strategies, anti-competitive practices, marketing policies and practice, as well as disclosure of R&D expenditures (e.g., report on the number of products in the R&D pipeline that are new versus enhanced versions of existing products) and lobbying/political activities with agendas that may restrict the access and affordability of medicines. For decades, ICCR members have pressed drug companies for greater disclosures on pricing structures as a way to promote greater access to medicines. A lack of transparency around how drug prices are determined has led to an industry-wide ethos of ``whatever the market will bear,'' which can lead to predatory pricing. We have asked companies to disclose the rates of price increases year-to-year of their top selling branded prescriptions drugs and to disclose the rationale and criteria used for these price increases. We have also asked the companies to assess the legislative, reputational and financial risks these increases represent for the companies. However, that lack of transparency still prevails. Most recently, we have become increasingly concerned about pharmaceutical companies' governance structures and their Boards' ability to proactively mitigate risk related to high drug prices. A 2017 Credit Suisse analyst report stated that ``US drug price rises contributed 100% of industry EPS growth in 2016'' and characterized that fact as ``the most important issue for a Pharma investor today.'' In response to this, in 2018 ICCR members filed resolutions at the companies highlighted in the 2017 Credit Suisse report asking ``the Compensation Committee (the `Committee') to report annually to shareholders on the extent to which risks related to public concern over drug pricing strategies are integrated into [company's] incentive compensation policies, plans and programs (`arrangements') for senior executives. The report should include, but need not be limited to, discussion of whether (i) incentive compensation arrangements reward, or not penalize, senior executives for adopting pricing strategies, or making and honoring commitments about pricing, that incorporate public concern regarding prescription drug prices; and (ii) such concern is taken into account when setting financial targets for incentive compensation arrangements.'' In other words, are executives incentivized to simply increase the price of drugs with no added benefit in clinical efficacy simply to meet short-term revenue targets? In particular, we are seeking better articulation of the goal-setting process and the translation of those goals into incentive pay targets. We would strongly encourage you, as members of the Senate Finance Committee, to also seek written answers to the following questions: How assumptions about price changes are incorporated when revenue goals are set; Whether any policy or guideline exists regarding the preferred proportion of revenue growth derived from price increases; Whether any policy exists regarding unplanned price increases that would enable revenue goals or compensation revenue targets to be met and whether the board has to approve such increases; and How the compensation committee uses revenue goals or estimates to produce the various target levels (e.g., minimum, target and maximum) used to determine incentive payouts. Mirroring Senator Wyden's concern that AbbVie's CEO's bonus is directly tied to the sales of Humira, we have also been asking why Humira sales are an appropriate measure for AbbVie's short-term incentive plan (STIP), and whether the company considers pricing increases when awarding STIP? AbbVie uses net revenue, income before taxes and Humira sales as metrics for the annual bonus and earnings per share (EPS) as a metric for certain long-term incentive awards to senior executives. For Pfizer, it is concerning to investors that the company publicly states that ``innovation in medicine has been and continues to be the cornerstone of the company,'' yet no pipeline metrics are included in the executive incentive agreements. In addition to increased disclosure on incentive structures, we have also asked companies to formalize board oversight of prescription drug pricing risk. For example, what is Pfizer's board oversight of drug pricing, or lack thereof, which may have led to the settlement of the co-pay kickback investigation and drug shortages due to manufacturing or market issues. A 2018 Credit Suisse report highlighted AbbVie as among the companies most at risk from specialty pricing pressures in commercial insurance. Humira, which accounted for 65% of AbbVie's revenues in 2017 now faces competition in Europe from biosimilars, which are expected to cost less. Therefore, robust board oversight of risks related to drug pricing would provide a valuable outside perspective and help ensure that those risks are being managed for the long term. Lastly, we also recognize that the strategy to expand monopolies without any meaningful new science is an unsustainable business model that exacts a heavy cost on patients and on the systems in which they seek care, and therefore, encourage companies to refrain from engaging in anti-competitive practices. As investors, we want the companies in which we invest to be successful in the long term, with sustainable business models that deliver value to customers and stakeholders. Because pharmaceutical companies derive their social license to operate from their contribution to public health, it is critical that their businesses--including their executive incentives structures--reinforce, not undermine, that social contract. After many years of investor engagement in an effort to promote greater access and affordability of medicines, today we seriously question the value pharmaceutical companies are delivering to their shareholders and to the greater public. If you have any questions, please contact, Meg Jones-Monteiro, Program Director--Health Equity, at [email protected] or (212) 870-2984. APPENDIX: 2019 ICCR EXECUTIVE INCENTIVES AND DRUG PRICING RISK RESOLUTIONS 2018 Companies: AbbVie, Amgen, Biogen, Bristol-Meyers Squibb, Eli Lilly 2019 Companies: AbbVie, Biogen, Bristol-Meyers Squibb, Celgene, Johnson & Johnson, Merck & Co, Pfizer, Vertex Example 2019 Resolutions: AbbVie (ABBV) _______________________________________________________________________ RESOLVED, that shareholders of AbbVie Inc. (``AbbVie'') urge the Compensation Committee (the ``Committee'') to report annually to shareholders on the extent to which risks related to public concern over drug pricing strategies are integrated into AbbVie's incentive compensation policies, plans and programs (together, ``arrangements'') for senior executives. The report should include, but need not be limited to, discussion of whether (i) incentive compensation arrangements reward, or not penalize, senior executives for adopting pricing strategies, or making and honoring commitments about pricing, that incorporate public concern regarding the level or rate of increase in prescription drug prices; and (ii) such concern is considered when setting financial targets for incentive compensation arrangements. Supporting Statement: As long-term investors, we believe that senior executive incentive compensation arrangements should reward the creation of sustainable long-term value. To that end, it is important that those arrangements align with company strategy and encourage responsible risk management. A key risk facing pharmaceutical companies is potential backlash against high drug prices. Societal anger over exorbitant prices and pressure over limited patients' access due to unaffordability may force price rollbacks and harm corporate reputation. We applaud AbbVie for committing not to increase prices by more than 10% for 2018, yet we are unaware of a like commitment for 2019 or beyond. Moreover, we are concerned that the incentive compensation arrangements applicable to AbbVie's senior executives may undermine any such commitment. AbbVie uses net revenue, income before taxes and Humira sales as metrics for the annual bonus and earnings per share (EPS) as a metric for certain long-term incentive awards to senior executives (2018 Proxy Statement, at 31). A 2017 Credit Suisse analyst report stated that ``US drug price rises contributed 100% of industry EPS growth in 2016'' and characterized that fact as ``the most important issue for a Pharma investor today.'' The report identified AbbVie as a company where price increases accounted for at least 100% of EPS growth in 2016 (Global Pharma and Biotech Sector Review: Exploring Future US Pricing Pressure, Apr. 18, 2017, at 1). It has been noted that the company's 2018 9.7% price increase for Humira could add $1.2 billion to the U.S. healthcare system (https://www.fiercepharma.com/pharma/drug-price-hikes-a-few-bad- actors-or-widespread-pharma?mkt_tok=eyJpljoiWWpZeFlt RTBOMIZoTkRJNSlslnQiOiJhckk2UONqNXBxNOx2UCtvdVdldzZVZXRIUHIrSOx ZOVRBNXdTV1FOeVNBSDMxb3NWUGJsRWtNcFROZmlPYmM5d2hXd3VuVOkld GICelBTYmk2). In our view, excessive dependence on drug price increases is a risky and unsustainable strategy, especially when price hikes drive large senior executive payouts. We believe that the company's strategy to use ``nursing support,'' which the California Department of Insurance claims in its suit against the company to be largely a kickback scheme to boost Humira sales, may have been better managed by leadership if Humira sales were not an explicit part of the payment incentive plan (https://www.law360.com/articles/1084008). The disclosure we request would allow shareholders to better assess the extent to which compensation arrangements encourage senior executives to responsibly manage risks relating to drug pricing and contribute to long-term value creation. We urge shareholders to vote for this Proposal. Merck & Co. (MRK) _______________________________________________________________________ RESOLVED, that shareholders of Merck & Co., Inc. (``Merck'') urge the Compensation and Benefits Committee to report annually to shareholders on the extent to which risks related to public concern over drug pricing strategies are integrated into Merck's incentive compensation policies, plans and programs (``arrangements'') for senior executives. The report should include, but need not be limited to, discussion of whether (i) incentive compensation arrangements reward, or not penalize, senior executives for adopting pricing strategies, or making and honoring commitments about pricing, that incorporate public concern regarding prescription drug prices; and (ii) such concern is considered when setting financial targets for incentive compensation arrangements. Supporting Statement: As long-term investors, we believe that senior executive incentive compensation arrangements should reward the creation of sustainable value. To that end, it is important that those arrangements align with company strategy and encourage responsible risk management. We are concerned that the incentive compensation arrangements applicable to Merck's senior executives may discourage them from taking actions that result in lower short-term financial performance even when those actions may be in Merck's best long-term interests. Merck has committed to limit average price increases of its drugs to no more than the rate of inflation (https://www.marketwatch.com/story/merck-to- lower-price-of-hep-c-treatment-zepatier-by-60-commits-to-responsible- pricing-2018-07-19), but incentive compensation arrangements may be inconsistent with that commitment. Merck uses revenue and pre-tax income as metrics for the annual bonus, and earnings per share (EPS) is a metric for performance share units granted after January 1, 2017 (2018 Proxy Statement, at 51, 61). A 2017 Credit Suisse analyst report identified Merck as a company where U.S. net price increases accounted for at least 100% of 2016 net income growth (Global Pharma and Biotech Sector Review: Exploring Future US Pricing Pressure, Apr. 18, 2017, at 22). In our view, risks to long-term value arise when large senior executive payouts can be driven by price hikes. Attention may focus on both high senior executive payouts and drug pricing, fueling public outrage. Ovid Therapeutics CEO Jeremy Levin has argued that incentives to boost short-term performance, such as EPS, lead executives to raise prices (and rebates to middlemen), starve research and development and buy back shares (https://www.biocentury.com/biocentury/strategy/2016-09-19/ why-jeremy-levin-says-executive-compensation-and-drug-pricing-must-). Incentives may have societal implications, as one critic of high pay for healthcare executives has noted: ``[I]f the most influential executives of these companies are being paid to keep that [cost] trajectory up, that's money that's being taken away from education or infrastructure or other parts of the economy that may not be growing as quickly, and maybe that we'd want to grow more quickly'' (https:// www.npr.org/sections/health-shots/2017/07/26/539518682/as-cost-of-u-s- heaIth-care-skyrockets-so-does-pay-of-heaIth-care-ceos). The disclosure we request would allow shareholders to better assess the extent to which compensation arrangements encourage senior executives to responsibly manage risks relating to drug pricing and contribute to long-term value creation. For example, it would be useful for investors to know whether incentive compensation target amounts reflect consideration of pricing pressures. We urge shareholders to vote for this Proposal. Pfizer (PFE) _______________________________________________________________________ RESOLVED, that shareholders of Pfizer Inc. (``Pfizer'') urge the Compensation Committee (the ``Committee'') to report annually to shareholders on the extent to which risks related to public concern over drug pricing strategies are integrated into Pfizer's incentive compensation policies, plans and programs (``arrangements'') for senior executives. The report should include, but need not be limited to, discussion of whether (i) incentive compensation arrangements reward, or not penalize, senior executives for adopting pricing strategies, or making and honoring commitments about pricing, that incorporate public concern regarding prescription drug prices; and (ii) such concern is considered when setting financial targets for incentive compensation arrangements. Supporting Statement: As long-term investors, we believe that senior executive incentive compensation arrangements should reward the creation of sustainable value. To that end, it is important that those arrangements align with company strategy and encourage responsible risk management. A key risk facing pharmaceutical companies is potential backlash against high drug prices. Pfizer has been criticized for repeated price increases, and in July 2018 President Trump called out ``Pfizer and others'' in a tweet, saying they ``should be ashamed that they have raised drug prices for no reason''; Pfizer then postponed planned increases. We are concerned that the incentive compensation arrangements applicable to Pfizer's senior executives may discourage them from taking actions, like foregoing price increases that result in lower short-term financial performance even when those actions may be in Pfizer's best long-term interests. Pfizer uses revenue and earnings per share (EPS) as metrics for the annual bonus and operating income as a metric for performance share awards (2018 Proxy Statement, at 66, 68). A 2017 Credit Suisse analyst report identified Pfizer as a company where U.S. net price increases accounted for at least 100% of 2016 net income growth (Global Pharma and Biotech Sector Review: Exploring Future US Pricing Pressure, Apr. 18, 2017, at 22). In its 2018 report, Credit Suisse characterized Pfizer's 2017 10% net price increase as above average for the industry and noted that its list price increases were the second highest (Global Pharmaceuticals: Scoring Sensitivity to Trump's Reforms, May 25, 2018, at 15, 20). In our view, excessive dependence on drug price increases is a risky and unsustainable strategy, especially when price hikes appear to drive large senior executive payouts. Highlighting this connection, a March 2018 article carried the headline, ``Pfizer CEO Gets 61% Pay Raise--to $27.9 Million--As Drug Prices Continue to Climb'' (https:// arstechnica.com/science/2018/03/amid-drug-price-increases-pfizer-ceo- gets-61-pay-raise-to-27-9-million/; see also https://www.usnews.com/ opinion/articles/2017-08-30/bernie-sanders-take-on-big-pharma-and- lower-prescription-drug-prices). We are concerned that large payouts based on financial metrics that can be affected by pricing create risks for Pfizer. The disclosure we request would allow shareholders to better assess the extent to which compensation arrangements encourage senior executives to responsibly manage risks relating to drug pricing and contribute to long-term value creation. For example, it would be useful for investors to know whether incentive compensation target amounts reflect consideration of pricing pressures. We urge shareholders to vote for this Proposal. ______ National Association of Free and Charitable Clinics 1800 Diagonal Road, Suite 600 Alexandria, VA 22314 Nicole Lamoureux, President and Chief Executive Officer Chairman Grassley, Ranking Member Wyden and Members of the Committee, my name is Nicole Lamoureux and I am the President and Chief Executive Officer of the National Association of Free and Charitable Clinics. Last month, I was sitting in the hearing room as the pharma executives testified. While I applaud Congress for finally getting these executives to speak, I noticed some important gaps in the conversation. During the hearing, both Congress and the pharmaceutical executives focused on a specific group of Americans: those with health insurance. Senate Finance Committee Chairman Grassley opened the hearing by describing how high list prices hurt ``those with high deductibles'' and ``taxpayers,'' but did not mention the uninsured. While we understand that the committee's focus remains largely on health programs within your jurisdiction that require significant federal investments, we believe that by not addressing the high cost of medication for the uninsured as well as the insured, the overall cost of health care will continue to increase. When medication costs are too high, uninsured individuals must forgo their medication or split doses, and often end up needing the emergency department for both the repercussions of missed prescriptions and for primary care. Research shows that 75 percent of all emergency department visits not resulting in admission are for non-emergencies that should be treated outside of the emergency room (Hwang et al. 2012). Patients who lack insurance and access to primary care are often forced to use the emergency room for routine medical needs. These emergency room visits are expensive, contribute to overcrowding, and drive up healthcare costs for everyone. Currently, there are 27 million Americans without insurance--about 1 in 12 people--and that number is growing. I know this group well. These are the people who receive access to health care and medication from the 1,400 free and charitable clinics in our country. Free and Charitable Clinics are safety-net health care organizations that utilize a volunteer/staff model to provide a range of medical, dental, pharmacy, vision and/or behavioral health services to economically disadvantaged individuals. Such clinics are 501(c)(3) tax-exempt organizations or operate as a program component or affiliate of a 501(c)(3) organization. Free or Charitable Clinics restrict eligibility for their services to individuals who are uninsured, underinsured and/ or have limited or no access to primary, specialty or prescription health care. Additionally, Free and Charitable Clinics receive little to no state funding and no federal funding, do not receive HRSA 330 funds, and are not Federally Qualified Health Centers or Rural Health Centers. Therefore, these clinics rely heavily on the generosity of individual donors, foundations and grants as funding sources. Even though our organizations do not receive federal funding, we are impacted by every decision that is made at the federal level, especially when it comes to medication affordability. In 2018, the 1,400 free and charitable clinics served 2 million Americans, with a total of 6.3 million patient visits. In the most recent data reported by our members, the number one concern for both our patient population and their providers is the high cost of medication. I understand why Medicaid and Medicare patients were the main focus of the testimony, but the needs of millions of uninsured Americans are also critical to the conversation about solving the pricing issues and inequities of the current healthcare system. When Congress asked the seven executives, ``Who pays list price?'' Merck CEO Ken Frazier responded by saying, ``There's a small percentage of people who have no insurance who could actually be charged the list price.'' He also said that in our current system, ``The poorest and the sickest are subsidizing others.'' Senator Daines summarized the issue this way: "So the people who can afford it the least, arguably, are paying the list price?'' Those who are paying the list price are our patients, the uninsured and underinsured in this country. The current minimum price of $150 for a vial of insulin is not affordable for a mother making the choice between putting food on her table or paying for her prescription. Our patients have no choice but to ration medications, taking lower doses of them or stopping them altogether. We have no shortage of these stories, from young adults eating less than they should to reduce the amount of insulin they need to parents starving themselves to afford insulin for their children. In our network of clinics, this is a lived reality. In a time when few issues are truly bipartisan, and health care continues to become ever more divisive, the exponential growth of drug prices is a rare issue that crosses the aisle. Needing insulin isn't red or blue, nor is using an EpiPen or depending on an inhaler to breathe. We need to harness this rare moment of unity and push for true progress. I know that Congress realizes how important it is to have the conversation to make medication more affordable once and for all, so we can fix this broken system. I want to make sure we get it right this time around. America's free and charitable clinics try to catch the people who slip through the cracks. If we don't stop this unchecked rise in the cost of medications, these cracks will widen until they threaten the foundation of our health care system. I appreciate the opportunity to submit my comments to the hearing record on behalf of the 2 million Americans who receive care at free and charitable clinics and look forward to answering any questions that the committee might have. Works Cited: Hwang, Liao, Griffin, and Foley. ``Do Free Clinics Reduce Unnecessary Emergency Department Visits?'' The Virginian Experience Journal of Health Care for the Poor and Underserved 23 (2012): 1189-1204. ______ National Business Group on Health 20 F Street, NW, Suite 200 Washington, DC 20001 202-558-3000 Fax 202-628-9244 www.businessgrouphealth.org Chairman Grassley, Ranking Member Wyden and members of the Senate Committee on Finance, thank you for the opportunity to submit a statement for the record on the large employers' perspective on drug pricing. The National Business Group on Health (NBGH or the ``Business Group''), whose members include 437 of the nation's largest employers, commend the Committee's effort to take a holistic look at the root causes of high and escalating drug prices. In addition to these, we anticipate submitting comments on subsequent hearings within the Committee's series on drug pricing. Along with the government, taxpayers and families, employers have a vested interest in improving the efficiency and effectiveness of health care delivery, which includes the delivery of pharmaceuticals. According to NBGH's 2019 Large Employers' Health Care Strategy and Plan Design Survey, almost half, 49% of respondents are taking an activist role in driving delivery system change.\1\ As part of this, more employers are scrutinizing the role of the pharmaceutical supply chain, as specialty pharmacy costs remain one of the top drivers of overall health care trend. Particularly as the growth of high-deductible plans over the past decade has put a spotlight on drug prices, employers have become increasingly frustrated by complexity within the supply chain, which could be described as a ``rebate-driven'' contracting model. --------------------------------------------------------------------------- \1\ 2019 Large Employers' Health Care Strategy and Plan Design Survey, National Business Group on Health. Nearly all employers believe the pharmaceutical supply chain model needs to change: 14% believe it needs to be more transparent. 35% believe rebates need to be reduced. 49% believe the model needs to be overhauled and simplified. Regarding the use of rebates as a mechanism to control drug costs: 75% do not believe drug manufacturer rebates are an effective tool for helping to drive down pharmaceutical costs. 91% would welcome an alternative to the rebate-driven approach to managing drug costs. The rapid pace at which reforms are being considered within the marketplace and by both legislative and regulatory bodies at the federal and state levels is encouraging. A focus of the hearing, the Administration's proposals to implement changes to how pharmaceutical reimbursement and contracting is administered within Medicare Part Band Part D illuminates the need and possibility that there are likely to be multiple solutions that improve upon the current model within the private and public sector. NBGH supports a model marked by transparency, and one that removes incentives to consistently increase prescription drug prices. However, we also urge cautious, thoughtful, and analytical approaches that comprehensively evaluate the impact to market dynamics for all supply chain stakeholders. Below, we highlight NBGH's perspectives on two of the widely discussed proposals. Our full comments on the International Pricing Index (IPI) model can be found online. Additionally, we intend to provide full comments on the rebate proposal by the April 8th deadline. International Pricing Index (IPI) Model \2\ --------------------------------------------------------------------------- \2\ ``International Pricing Index (IPI) Model,'' Center for Medicare and Medicaid Innovation, accessed March 11, 2019. --------------------------------------------------------------------------- We must take a broad perspective to assure that public policy decisions contribute to overall cost control and quality improvement for all Americans. We commend the Administration's commitment to lowering the cost of prescription drugs and encourage it to seek solutions. However, we strongly recommend that whatever CMS adopts, part of the consideration and criteria for evaluating the results must be the impact on the private market and the 170 plus million people covered by employers and insurers and not limited to the impact on Medicare alone. If we as a nation are to succeed in controlling health care costs, we must ensure that public policy decisions do not merely ``squeeze the cost balloon'' in one area only for it to expand and exacerbate the problem in another area. Our chief concern centers on the ANPRM's proposal to link reimbursement rates to other nations' prices. Apart from the fact that these nations determine prices differently, have different patent and exclusivity models, and often vastly different incentives for biosimilar utilization, we are concerned that the impact on prices for the same pharmaceuticals in the US may rise in the private sector and the market for biosimilars may be adversely impacted if Medicare adopts this approach. Rebate Reform Proposal \3\ --------------------------------------------------------------------------- \3\ ``Fraud and Abuse; Removal of Safe Harbor Protection for Rebates Involving Prescription Pharmaceuticals and Creation of New Safe Harbor Protection for Certain Point-of-Sale Reductions in Price on Prescription Pharmaceuticals and Certain Pharmacy Benefit Manager Service Fees'' (Federal Register, February 6, 2019). --------------------------------------------------------------------------- Many large employers have already begun evaluating the utility of point-of-sale rebates as part of their benefit design and a subset (29 percent) have them in place today. Thus, HHS's proposal picks up on the momentum from large employers and, more importantly, underscores the inefficiency of the pharmaceutical supply chain. Given the market momentum on this issue, to both lower out-of-pocket costs for patients and evaluate ways to simplify a complex system, the Business Group is in favor of market-based solutions relative to point-of-sale rebates. NBGH has the following serious concerns about proposals around rebates. While the stated goal of these proposals is to lower prescription drug prices and out-of-pocket costs for consumers by encouraging PBMs to pass discounts from drug manufacturers directly on to consumers and bring transparency to prescription drug market, we have various concerns with the proposals including but not limited to the following: The proposals focus on out-of-pocket costs only. The intent of the proposed rule and companion legislation is to lower out-of-pocket costs at the pharmacy counter and add needed pricing transparency to the market. While we support the proposed increased transparency and pricing relief for patients, we urge policy makers to avoid ``quick fixes'' that focus only on out-of-pocket costs, as opposed to total cost to the system. Focusing on out-of-pocket costs only has the potential to mask root causes of price increases, potentially lead to even higher increases over time, and drive the escalating trend on drug expenditures. Any changes in supply-chain contracting should not result in a net increase in drug costs to any payor, nor windfall to any supply chain stakeholder. Medicaid and CHIP Payment and Access, the Congressional Budget Office Commission (MACPAC) staff have noted that the CMS Office of the Actuary (OACT) estimated a net increase in Medicaid drug spending of $200 million over 10 years if the proposed rebate rule is finalized. A large chunk, if not the largest chunk, of this expected increase would come from the decline in inflation-based rebates.\4\ Further, manufacturer claim liabilities through the coverage gap discount program (CGDP) would be lower, which would produce an overall substantial savings for manufacturers.\5\, \6\ While savings is expected, that savings should be realized comprehensively across both the supply and demand sides of the pharmaceutical supply chain. --------------------------------------------------------------------------- \4\ ``Proposed Safe Harbor Regulation Impact'' (Office of the Actuary, August 30, 2018). \5\ Manufacturer payments through the CGDP are expected to be about $2 billion per year lower on average. When POS costs are lower, it takes longer for he costs to accumulate toward the initial coverage limit (ICL) and the TrOOP threshold. CGDP payments would be lower as fewer members would be calculated as a percentage of a lower POS cost, but the impact would vary by manufacturer and by plan sponsor. \6\ ``Impact of Potential Changes to the Treatment of Manufacturer Rebates'' (Milliman, Inc., January 31, 2019). The proposals do nothing to address list prices. The proposed rule ``intends'' and speculates that manufacturers might lower list prices, but there is little assurance that manufacturers will offset rebates with price reductions. In fact, at the hearing, not all CEOs in attendance would affirmatively state this would be the case at all, due to antitrust case law.\7\ --------------------------------------------------------------------------- \7\ ``Foley Hoag LLP white paper, ``Antitrust Implications of a Proposed HHS Rule to Limit Manufacturer Rebates,'' accessed March 11, 2019. The proposed timeline within the HHS proposal is arguably too aggressive. PBMs have largely already concluded negotiations on price concessions for plan year 2020 and are in the middle of actuarial analysis to prepare bids. There is no way to renegotiate in time to know the associated costs in order to bid properly, and it would be --------------------------------------------------------------------------- impossible to retool the supply chain in such a short period of time. Premiums will increase. The proposals are projected to increase the cost of healthcare for those who don't use drugs having rebates, through premium increases, while disproportionately decreasing costs for those who do use drugs with discounts. Thus, while we agree that the rebate-driven model is ripe for reform and ineffective at controlling drug prices, we are concerned about the unintended consequences associated with the proposals as written. In addition to contracting concerns within the rebate-driven model, there remains substantial opportunity for policy change relative to prescription drug prices, most of which would encourage a more competitive and dynamic market with correspondingly more affordable prices. Advance Policies to Promote More Affordable, Financially Sustainable Prescription Drug Pricing While many of the recommendations below are directed toward various agencies in the Administration, several of them require Congressional action. All of these policy recommendations are highlighted in the National Business Group on Health's Issue Brief on Policy Recommendations to Promote Sustainable, Affordable Pricing for Specialty Pharmaceuticals. Remove Uncertainties Surrounding Risk-based and Value-Oriented Contracting and Implement Indication Specific Pricing and Reference Pricing in Public Programs: - Consider exemptions for value-based contracts from Medicaid best price requirements and clarify how drug makers and payers can conceive of value-based contracts without triggering broader Medicaid best price program implications. - Allow for variable pricing, where the price better reflects the evidence for benefit. - Evaluate the usefulness and application of the existing developed value frameworks and their potential to impact drug pricing in public programs, as well as their overall utility to the health care system. - Directly link reimbursement and improved patient outcomes. - Consider how drug makers and payers can enter into other types of innovative VBP arrangements, such as indication-specific pricing. - Implement reference pricing policies supported by clinical evidence consistently across public programs, where possible. Limit Reach of Medicare Part D Protected Classes: - Following the MedPAC's recommendations, the Congress and CMS should limit legislative and regulatory restrictions on formulary design within protected classes by modifying the Medicare Part D rules to remove those protected classes where enough generic competition exists, a change that would give private plans more freedom to control their formularies and negotiate for expanded manufacturer rebates. - Specifically, CMS should resubmit its proposal to remove antidepressants, antipsychotics, and immunosuppressants for transplant rejection from the list of protected classes because, in these classes, price reductions have been more closely linked with the availability of generics than to their status as ``protected'' and stand firm against industry-funded campaigns that seek to undermine the agency's data- driven proposal to increase competitive pricing. - At a minimum, policy makers should evaluate the potential anticompetitive influence of protected classes on the commercial market, and specifically, evaluate the limitations imposed on private payers' ability to negotiate competitive prices for drugs in the protected classes due to market spillover. Eliminate Perverse Payment Incentives Under Medicare Part B: - Eliminate financial incentives for prescribing more expensive medicines, in more expensive settings. - Establish direct links between reimbursement and improved patient outcomes. - Encourage manufacturers to assume some financial risk for use of high-priced drugs. Encourage the Uptake of Biosimilars: - Consider the utility of having an ``interchangeability'' distinction and potential alignment with the European biosimilars model, which has no such distinction. - Work with stakeholders to disseminate provider and patient education to firmly establish the safety and efficacy of biosimilar drugs to their reference products, recognizing that key successes to the uptake of biosimilar medicines in other countries was predicated on the creation of trust and confidence among all the stakeholders involved, such as prescribers, pharmacists, and patients. - Maintain payer autonomy to implement utilization management tools for specialty pharmaceuticals, including tools that pertain to biosimilar products. Reform Permissive Patent and Exclusivity Protocols: - Reduce the market exclusivity period for biologics from 12 years to 7 years. - Eliminate or limit additive patent extensions and exclusivity periods that serve only to extend monopoly power, especially where there is limited, or no additional company investment or patient value produced. - Develop sound policy that would discourage patent abuses such as ``evergreening'' and ``product hopping.'' These policies may include financial penalties, loss of exclusivity periods and/or reduced patent terms for other products. - Refine the biosimilars patent dance to effectively incentivize the use of the section 351(1) patent dispute resolution provisions. Reject anticompetitive ``quick fixes'': - As consumers find themselves paying more of their drug costs, it's tempting to be lured into new policies which may only further contribute to an anticompetitive climate. These policies may include specialty drug price caps, out-of-pocket payment caps, limitations on utilization management tools and mandated disclosure of propriety information. - Additionally, a federal law permitting importation nationwide could lead to some price reductions for both payors and patients in the short-term but, as markets adapt, it is unclear what the long-term effect on prices would be. It would also likely require a significant boost in resources for the Food and Drug Administration (FDA) to monitor imports and assure safety. The National Business Group on Health, representing 437, primarily large, employers (including 70 of the Fortune 100) who voluntarily provide valued health benefits and other health programs to over 55 million American employees, retirees, and their families, looks forward to working with you on our shared goals for health care: lower costs, improved access, and higher quality--umbrella goals we consider inclusive of prescription drugs. Please contact Steven Wojcik, the National Business Group on Health's Vice President of Public Policy, at (202) 558-3012, if you would like to discuss our comments in more detail or if we can provide additional information as the Committee continues its evaluation of drug pricing. Sincerely, Brian J. Marcotte President and CEO ______ National Coordinating Committee for Multiemployer Plans 815 16th Street, NW Washington, DC 20006 Telephone: (202) 737-5315 Michael Scott, Executive Director The National Coordinating Committee for Multiemployer Plans (the ``NCCMP'') appreciates the opportunity to provide comments to the Committee on the issue of prescription drug pricing and the challenges that multiemployer group health plans face in today's environment. We also appreciate the efforts of the Committee to promote discussion of solutions to America's problem of the high cost of prescription medications. Background on the Multiemployer Plans and the NCCMP Multiemployer plans are a product of the collective bargaining process, where at least one labor organization and two or more employers provide health, pension and a variety of other employee benefits through negotiated contributions to trust funds that are required by law to be maintained for the ``sole and exclusive benefit'' of plan participants. Multiemployer plans are jointly trusted by both labor and management and are subject to applicable provisions of the Taft-Hartley Act, ERISA, and the Internal Revenue Code. The NCCMP is the only national organization devoted exclusively to protecting the interests of the over 20 million active and retired American workers and their families who rely on multiemployer plans for retirement, health, and other benefits. The NCCMP is a nonprofit, non-partisan organization with members, plans, and contributing employers in a broad range of industries, including agriculture, building and construction, bakery and confectionary, entertainment, health care, hospitality, longshore, maritime, mining, retail food, service, steel, and trucking. The NCCMP's purpose is to assure an environment in which multiemployer plans continue their vital role in providing benefits to working men and women. Multiemployer health plans are often self-insured and plan sponsors contract with both medical and pharmacy benefit managers to provide administrative services. These plans provide benefits to both active workers and their families, and to retirees. Consequently, multiemployer plans will often contract with a Medicare Part D Prescription Drug Plan or Medicare Advantage plan to provide prescription drug and other benefits to retired participants. Prescription Drug Prices Continue to Rise Most multiemployer health plans provide prescription drug coverage to active employees, dependents, and retirees. Prescription drug costs are a significant part of health plan expenses. Multiemployer plan sponsors have looked to a variety of means to lower drug prices. Strategies include increased use of step therapy, prior authorization, quantity limits, formularies (which exclude certain drugs) and other utilization management techniques. However, prescription drug cost increases are primarily driven by price increases, not increased utilization.\1\ Drug price inflation is a significantly greater component of projected prescription drug price trend than utilization. In addition, specialty drug price increases are projected to be in the double digits for 2019, a significant and concerning pattern because specialty drugs now account for as much as 35 percent of total pharmacy spending.\2\ New specialty brand drugs to treat serious illnesses contribute to the cost increase, and there are limited opportunities to substitute generic drugs in therapeutic classes dominated by single-source specialty brand drugs. Consequently, plan sponsors cannot effectively control prices through utilization controls alone. --------------------------------------------------------------------------- \1\ 2019 Segal Health Plan Cost Trend Survey, available at http:// www2.segalco.com/me-trend-survey-20l9.pdf. \2\ Id. --------------------------------------------------------------------------- Areas for Congressional and/or Regulatory Inquiry and Action The NCCMP recommends that the Committee take action to promote transparency in the rebate system while ensuring that action taken on the rebate side of the pricing equation results in lower--not higher-- drug prices paid by plan sponsors and consumers. In addition, we emphasize the NCCMP's commitment to eliminating the tax that penalizes plan sponsors and workers for the high costs of health care (including drug costs) beyond their control. Rebates and Transparency Rebates account for a substantial portion of the drug pricing equation. Rebate offsets that are passed through to multiemployer plan sponsors from pharmacy benefit managers (PBMs) help to lower net plan cost trends. However, multiemployer plans must aggressively monitor PBMs to assure that rebates are actually passed through to the plan, and in many cases, the rebate structure is opaque and impenetrable. Pricing structures also change frequently, as can be seen by some of the PBMs ``market pricing'' strategies, which adjust prices, rebates, and participant cost sharing based on market price variations for certain drugs. State legislators are increasingly attempting to rein in drug costs by passing laws requiring greater transparency. However, those laws may not be effective, either because the states cannot tackle the problem alone, or the laws will be subject to multiple challenges by pharmaceutical manufacturers and PBMs. As a core principle of ERISA, employee benefit plan fiduciaries need information concerning all compensation to be received by a service provider and any conflicts of interest that may adversely affect the service provider's performance under the contract or arrangement. In 2014, the NCCMP provided supporting testimony to the ERISA Advisory Council, which was studying PBM Compensation and Fee Disclosure.\3\ At that time, we suggested that plan fiduciaries would be well served if PBMs were required to disclose all instances in which they receive financial remuneration from drug manufacturers, retail pharmacy providers, and data managers. The disclosures need to be sufficient to allow trustees to assess whether, and to what extent, the services offered by the PBMs are in the best interest of plan participants, rather than simply furthering the financial interests of the PBM. Transparency continues to be a concern to plan sponsors and efforts of the Committee to increase transparency for rebates and financial arrangements between PBMs and pharmaceutical manufacturers would assist multiemployer plans in efforts to control prescription drug prices. --------------------------------------------------------------------------- \3\ https://www.dol.gov/sites/default/files/ebsa/about-ebsa/about- us/erisa-advisory-council/2014-pbm-compensation-and-fee-disclosure.pdf. More attention is being paid of late to the rebate system and the important role that it plays in determining the prices that plan sponsors and consumers pay for prescription drugs. But rebates are only part of the equation. The list price that drug manufacturers set for their prescription drugs is the starting point for the negotiation between manufacturers and PBMs over rebates. More transparency in the setting of list prices could help to put some downward pressure on those prices. But if list prices continue to go up while rebates go down, plan sponsors and consumers will end up paying more. As a result, it is essential that any action taken to address the rebate structure not have the unintended consequence of actually increasing what plan sponsors and consumers pay for prescription drugs. Eliminating the Unfair Tax on Health Plan Coverage For decades before the enactment of the Patient Protection and Affordable Care Act (ACA), the majority of Americans with health coverage received their coverage through employment. This has remained the case well after the ACA first went into effect. Today, over 181 million Americans have employment-based health coverage, which includes coverage under multiemployer plans. The 40 percent excise tax under Internal Revenue Code section 49801, enacted as part of the ACA, threatens these hard-working Americans with a steep and unfair tax on their health coverage. Sometimes popularly (although inappropriately) referred to as the ``Cadillac plan'' tax, the original intent of the tax was to impact plans with ``gold-plated coverage.'' In actuality, however, the tax will have a much broader impact on even modest plans as a result of underlying medical inflation. Employers understand that quality health care is an investment in employees and not simply a monetary benefit. At the same time, both employers and employees recognize that the cost of health care cannot become so great that it makes employers non-competitive. This marketplace reality is the reason that the vast majority of private plan sponsors have utilized cost containment strategies for decades to manage and stretch finite compensation dollars as much as possible. Unfortunately, the high and ever-increasing health care costs faced by the private sector are directly amplified by the U.S. Government through its own health care programs, statutes, and regulatory requirements. As the largest provider and purchaser of health care in the U.S. through Medicare and Medicaid, programs that collectively spend more than $1.2 trillion annually,\4\ the U.S. Government's longstanding policy of significantly under-compensating health care providers results in these providers charging more to their private sector clients in order to recoup their uncompensated federal expenses. In this way, the private sector subsidizes Medicare, Medicaid, and the U.S. Government by absorbing these uncompensated expenses through higher costs and premiums. --------------------------------------------------------------------------- \4\ In 2017, Medicare spending grew 4.2% to $705.9 billion in 2017 and Medicaid spending grew 2.9% to $581.9; https://www.cms.gov/ research-statistics-data-and-systems/statistics-trends-and-reports/ nationalhealthexpenddata/nhe-fact-sheet.html. The simple fact is that the high costs of employment-based health plans and medical inflation are not driven by employment based health plans themselves, but by other factors, including the actions (and inactions) of the U.S. Government. Congress should continue to work to address medical care inflation, including rising drug costs, while maintaining good health care outcomes and quality of care. Congress should not penalize employers, health plans, or employees and their families through unfair taxes. If the excise tax is imposed, the end result will not be an overall reduction in health care costs, lower medical inflation or higher federal tax revenue; rather it will be borne by hardworking Americans through cost-shifting and foregoing needed care. Additionally, as employment based healthcare is penalized, it will become increasingly unavailable to those currently covered, which will increase federal spending on subsidies and Medicare as a significant portion of the currently covered workforce is eligible for these --------------------------------------------------------------------------- programs. NCCMP appreciates the actions Congress has taken in the past to help prevent the imposition of the 40 percent excise tax by delaying it twice, so that the effective date is now pushed back to 2022. Delays, however, are not sufficient to prevent the harmful impact of this tax. In calling for repeal, NCCMP joins the voices of a large, diverse group, as evidenced by a recent letter to Congress signed by over 550 organizations representing such interests as public and private sector employers across a wide range of industries, non-profit organizations, chambers of commerce, unions, and patient groups. We support the bi- partisan Middle Class Health Benefits Tax Repeal Act of 2019, recently introduced in the Senate by Senators Heinrich (D-NM) and Rounds (R-SD) and co-sponsored by many others, including members of this Committee. We also support the House version of the bill, which was introduced in January and which as of this writing has 229 co-sponsors, with growing numbers. The NCCMP recommends fully and immediately repealing the 40% excise tax on employer sponsored health coverage and also opposes any efforts to tax employees on their health care benefits. ______ Oxfam America 1101 17th Street, NW, Suite 1300 Washington, DC 20036 Tel +1 (202) 496-1180 | Fax +1 (202) 496-1190 | www.oxfamamerica.org February 26, 2019 Mr. Chairman, Ranking Member and Members of the Committee, Oxfam appreciates the Committee's sincere intention to ensure affordable and accessible medicines for all who need them. We would like to take this opportunity to bring the Committee's attention to our recent investigation, Prescription for Poverty,\1\ illustrating how four major pharmaceutical firms (three of whom are testifying before the Committee at this hearing) may well be underpaying their US taxes to the tune of $2.3 billion annually by systematically stashing their profits in overseas tax havens. On top of these tax losses from offshore tax avoidance, these companies likely benefitted significantly from the Tax Cuts and Jobs Act (TCJA).\2\ --------------------------------------------------------------------------- \1\ Oxfam, ``Prescription for Poverty: Drug companies as tax dodgers, price gougers, and influence peddlers,'' Sept. 2018 at https:/ /www.oxfamamerica.org/explore/research-publications/prescription-for- poverty/. \2\ Report of the Senate Finance Committee Democratic Staff, ``Trump Tax Law and the Health Care Industry: A $100 Billion Bonanza,'' April 17, 2018. Here in the US and around the world, in rich and poor countries alike, high drug prices are causing too many people to sacrifice their savings or worse--their lives--to enrich executives at highly profitable and --------------------------------------------------------------------------- influential drug companies. As is well known, these drug companies' very business model depends to a large degree on American taxpayer dollars: to pay for essential front-end drug research, to protect patents and intellectual property, and to purchase their drugs through Medicare, and the Veteran's Administration. Yet, these same companies are undermining public trust (and their very own business model) by steadily under-paying their taxes, in the US and around the world. Scouring the companies' financials, we've found that four major pharmaceutical firms--Abbott, Johnson & Johnson (JNJ), Merck (MRK), and Pfizer (PFE)--alone appear to have deprived rich and poor countries alike of around $3.7 billion of vital revenue that could have been spent on vaccines, midwives, or health clinics. Because the companies reveal little financial information about their subsidiaries, Oxfam's investigation barely scratches the surface. Yet even a small sampling reveals a striking degree of tax avoidance through profit- shifting. As the largest market for the four pharmaceutical companies, the United States is the biggest loser from tax avoidance by these companies, to the tune of an estimated $2.3 billion a year: $1 billion by JNJ, $589 million by Pfizer, $533 million by Merck, and $143 million by Abbott. Together, this is enough to pay for health insurance for nearly a million low-income children in the US. How are companies avoiding their tax responsibilities? Oxfam examined publicly available data on subsidiaries of four of the largest US drug companies and found a striking pattern. In the countries analyzed with standard corporate tax rates, the companies reported low pre-tax profits--7 percent profits on average in high- income countries, and 5 percent on average in seven low- and middle- income countries. In contrast, these corporations reported annual global profits of up to 30 percent. So, where were these companies reporting such sky-high profits? Tax havens. In four countries which charge very low or no corporate tax rates, these companies posted 31 percent profit margins--suggesting that the companies are artificially shifting their profits to avoid paying taxes in countries with higher tax rates. In the case of the pharmaceutical giants, the ploy may involve ``domiciling'' their patent, not in the corporation's home country where the drug was actually developed, but in a tax haven-where a company's presence may be as little as a mailbox. That subsidiary then charges hefty licensing fees to subsidiaries in other countries. The fees are a tax deductible expense in the normal jurisdictions, meaning that they can be used to offset any earnings and thereby lower the reported profits. At the same time, the fee income accrues to the subsidiary in the tax haven, where it is taxed lightly or not at all. The company's overall tax payment then is lowered, sometimes significantly. Another technique many companies have used is to sell their production or services not directly to the countries where they will be consumed, but to ``pivot'' companies in low tax jurisdictions that then resell them at a profit to affiliated distributors. This practice creates an artificial profit that remains in the tax haven. Most of the time, these are only paper transactions--the goods are shipped straight from the factory in the production country to the warehouse in the consumption country--but the transactions allow profits to move from one country to another almost tax-free. Because companies refuse to release their full country-by-country financial reports to the public, and many governments have yet to make these reports public, the information on tax dodging is far from complete. Yet, the pattern of Big Pharma's tax practices is consistent: this is either an astounding coincidence or the result of using accounting tricks to deliberately shift profits from where they are actually earned to tax havens. Pfizer, Merck, and Abbott are among the 20 US corporations with the greatest number of subsidiaries in tax havens; Johnson & Johnson is not far behind. While profits can vary from country to country for any number of legitimate reasons, it is highly unlikely that these explanations can fully account for the consistent pattern of much higher profits being posted in countries with very low tax rates where these corporations do not sell the majority of their medicines. Tax injustice and price gouging are two sides of the same coin Tax avoidance and price gouging are not, in fact, completely independent phenomena. Today's hearing provides a timely opportunity to connect the dots between high drug prices and unjust tax avoidance practices which deprive the US Treasury of precious public revenue needed to fund essential public health programs in the US. Every tax dollar avoided means a tax dollar less for new drug research at the National Institutes of Health, and for essential health insurance programs like Medicaid, Medicare and the Child's Health Insurance Program. What's more, as we detail in our report cited above, a cornerstone of these companies' business model--the intellectual property rules protecting many of these pharmaceutical companies' most profitable products--is a central factor in allowing these companies to drive up drug prices, while driving down their tax payments. And conversely, our tax system at present incentivizes price hikes in a variety of ways. While the specific solutions to drug pricing and tax avoidance are distinct, there are some essential common approaches in our view. Global companies should be transparent about where they earn and spend their money, they should pay tax in alignment with actual economic activity rather than abuse our tax system in a variety of ways, and they should use their political influence responsibly, rather than undermining governments' efforts to provide essential medicines and healthcare for us all. ------------------------------------------------------------------------ ------------------------------------------------------------------------- In this context, we would encourage the Senate Committee to raise the following questions to JNJ, PFE and MRK during the February 26th hearing: 1. According to evidence received, your companies systematically report low pre-tax profits in high-tax countries, and high pre-tax profits in low-tax countries: reportedly resulting in billions of dollars of lost revenue in the US which could have been spent on new drug research or to fund essential healthcare. Can you explain why these aggressive tax planning practices serve the public interest? 2. Is your company involved in offshore tax avoidance? If so, please explain why you believe this is acceptable practice. Can you commit to publicly releasing your company's country-by-country financial reports to show and prove your tax practices meet social expectations? 3. How has your company invested the fresh cash resulting from the passage of the TCJA? Very concretely, can you explain how these expenditures are working to drive down drug prices? If they are not doing so, why not? ------------------------------------------------------------------------ For any questions, please contact Nicholas J. Lusiani, Senior Advisor at [email protected], or (202) 777-2912. ______ Patients for Affordable Drugs Now Statement by David Mitchell, Founder Chairman Grassley, Ranking Member Wyden, and members of the Senate Finance Committee, Thank you for your leadership to address the problem of high drug prices in America. U.S. patients and taxpayers spend more than $450 billion \1\ each year on prescription drugs. By some estimates, nearly one-fifth \2\ of all health care costs go toward prescription drugs. The main driver of prescription drug spending is patent-protected brand-name drugs, which make up only about 10 percent \3\ of prescriptions but account for three-quarters of drug spending.\4\ --------------------------------------------------------------------------- \1\ https://www.finance.senate.gov/imo/media/doc/ 29JAN2019MILLERSTMNT.pdf \2\ https://www.ncbi.nlm.nih.gov/pubmed/27552619. \3\ https://docs.house.gov/meetings/GO/G000/20190129/108817/HHRG- 116-GOOO-Wstate-KesselheimA-20190129.pdf. \4\ https://docs.house.gov/meetings/GO/G000/20190129/108817/HHRG- 116-GOOO-Wstate-KesselheimA-20190129.pdf. That's why today's hearing is so important. You have called CEOs of seven major drug corporations before the Senate Finance Committee to explain their pricing practices, patent thickets and the fact that American patients and taxpayers pay anywhere from two to six times \5\ more than the rest of the world for brand name prescription drugs. --------------------------------------------------------------------------- \5\ https://www.cnn.com/2015/09/28/health/us-pays-more-for-drugs/ index.html. We hear every day from patients suffering under the high cost of prescription drugs--cutting pills in half, choosing between groceries --------------------------------------------------------------------------- and medication, and simply going without. Patients have questions for the CEOs in front of you today, and we hope Congress will ask them. AbbVie Inc, About AbbVie: AbbVie's anti-inflammatory drug Humira is the top-selling \6\ drug in the world. The drug company doubled the price \7\ from about $19,000 per year in 2012 to $38,000 per year in 2018. AbbVie secured over 100 patents \8\ on Humira, ensuring that patent thickets will keep competition off the U.S. market, while the company cut the price in Europe by 80 percent \9\ for the exact same drug. --------------------------------------------------------------------------- \6\ https://www.nytimes.com/2018/01/06/business/humira-drug- prices.html. \7\ https://www.nytimes.com/2018/01/06/business/humira-drug- prices.html. \8\ https://www.bloomberg.com/news/articles/2017-09-07/this-shield- of-patents-protects-the-world-s-best-selling-drug. \9\ https://www.axios.com/abbvie-cuts-humira-price-europe- biosimilars-cc2d3d61-5782-4042-8c24-b322ea8285b4.html. Questions: Is it fair that Europeans have access to a less expensive biosimilar competitor for Humira, but your company bragged \10\ about blocking that competition in the U.S.? --------------------------------------------------------------------------- \10\ https://www.nbcnews.com/nightly-news/video/world-s-best- selling-drug-costs-five-times-more-in-u-s-than-europe-1445064259924. --------------------------------------------------------------------------- Do you partake in pay for delay or deals for delay? Do you support the Preserve Access to Affordable Generics and Biosimilars Act (S. 64)? Since Humira has already been very successful with more sales than the revenue of eBay,\11\ will you commit to holding the price of Humira steady until a biosimilar comes to market? --------------------------------------------------------------------------- \11\ https://www.axios.com/humira-2018-revenues-drug-prices- eb637e1f-09ae-479a-91ca-870edf7f5b4a.htm. Patient Stories: James Baer from Aurora, CO: ``I have seropositive degenerative rheumatoid arthritis, and am on a regimen of high cost drugs. Humira is the most expensive, at $4,500-$6,500 a month. My insurance, Humana, is refusing to pay for it starting next month. My doctor says I need it to win my fight against this genetic defect.'' Jacquie from Iowa: ``Since my Crohn's diagnosis, I've taken Lialda and Humira. Both drugs would have been astronomical if I hadn't been for my good insurance and eligibility for the pharmacy savings programs for each. I have been lucky. But I am always constantly worried about no longer being able to work due to my health, or losing my health insurance, making these essential drugs unaffordable.'' Sherry from North Carolina: ``I am unable to afford the biologic Humira even on Medicare. My monthly copay went from $5/month to $1,200/ month.'' Pfizer About Pfizer: Pfizer's history of price hikes is as staggering as it is long. Here's a look at the last three years: In 2017,\12\ Pfizer raised the price of 91 drugs by 20 percent--that was nearly 10 times the rate of inflation. In mid-2018,\13\ Pfizer announced price hikes on about 100 prescription drugs. After temporary freezes, Pfizer raised the raised the price of 40 drugs in January 2019.\14\ --------------------------------------------------------------------------- \12\ https://www.ft.com/contenUb2eOdd80-47ab-11e7-8519- 9f94ee97d996. \13\ https://medcitynews.com/2018/07/pfizer-increases-prices-on- 100-drugs/. \14\ https://www.cnn.com/2018/11/16/business/pfizer-drug-prices/ index.html. --------------------------------------------------------------------------- Questions: Will you commit to limiting the increase in list price of your drugs to the rate of inflation? Will you commit to submitting to this committee at the end of this year (2019) a report of the ways you have utilized the $10 billion stock buyback \15\ to serve patients? --------------------------------------------------------------------------- \15\ https://www.axios.com/pharma-share-buyback-tax-reform- 40a30b93-6149-4c67-bd6cd50-5ee814215.htm. --------------------------------------------------------------------------- Patient Stories: Helen Sgarlat from Kingston, PA: ``Because of the $600 price tag, I had to switch medications. I switched from Spiriva to one that's not working as well, Singulair. This is outrageous.'' Sharon from Iowa: ``I can't eat any more! My Keppra costs $460, Pradaxa $400, Lyrica $360. If drug prices came down, I would be able to eat again.'' Susan from Nevada: ``My sister has metastatic breast cancer taking Ibrance. Her co-pay is $2,290/month! Without this [drug] her cancer will spread! She received a short term grant to help but has to reapply to keep receiving. This is a lifesaving drug . . . must be more affordable!'' Sanofi About Sanofi: Almost 30 million\16\ Americans live with diabetes and 6 million need insulin to survive. From 2010 to 2015, Sanofi raised the price of the lifesaving diabetes drug Lantus by 168 percent.\17\ --------------------------------------------------------------------------- \16\ https://www.cbsnews.com/news/insulin-prices-rise-yet-again- causing-diabetics-to-cry-foul/. \17\ https://www.nytimes.com/2016/02/21/opinion/sunday/break-up- the-insulin-racket.html. --------------------------------------------------------------------------- Questions: If PBM rebates were eliminated, would you lower your list prices? Will you commit to undoing the dozens of times you've raised the price of Lantus and lower the list price this year? As the Chairman of the lobbying group, PhRMA, your organization spent $27.5 million on lobbying in 2018.\18\ Next year, will you agree to take half that money and use it to lower drug prices across the board for patients? --------------------------------------------------------------------------- \18\ https://www.statnews.com/2019/01/22/phrma-spent-a-record- breaking-27-5-million-on-lobbying-in-2018-new-filings-show/. --------------------------------------------------------------------------- Patient Stories: Jerraline Krawetzki from Berlin Heights, OH: ``Because of diabetes type 2, Lantus and Humalog are required. Because of the increased costs of these medications, after filling the first prescriptions, already IN the donut hole. This means a one month prescription of these 2 drugs, will cost over $600 per month. Senior citizens on a fixed income cannot afford this.'' David from Nevada: ``I have to take Lantus and Januvia for my Diabetes and Xeralto for my AFIB and many other medications for my heart, blood pressure, cholesterol, and BPH. These medications are very expensive and I can't afford them after I reach the Medicare Part D donut hole. Medicare prohibits free medications or discounts so living on social security means I will eventually die from lack of medicine.'' Jeannie from Kansas: ``I am a type 2 diabetic. I take Lantus insulin. One month supply is $128 with insurance. I am single and on Social Security of $942 a month. How am I to pay for the insulin that keeps me alive?'' Merck & Co. Inc. About Merck: Merck is no stranger to drug price increases. From January 2017 to mid-2018, Merck raised the price of Januvia by nearly 20 percent.\19\ In November 2018, the corporation raised the price on five drugs,\20\ including top-selling Gardasil and Keytruda. --------------------------------------------------------------------------- \19\ https://www.latimes.com/business/hiltzik/la-fi-hiltzik-drug- prices-20181206-story.html. \20\ https://www.reuters.com/article/us-merck-co-drugprices/merck- raised-prices-five-drugs-including-keytruda-in-november-idUSKCN1NX2ZN. --------------------------------------------------------------------------- Questions: Will you submit, for the record, the cost of research and development for the drug Keytruda, which reaped \21\ a total of $1.89 billion the third quarter of 2018 alone--an increase of 80% since 2017? --------------------------------------------------------------------------- \21\ https://www.bloomberg.com/news/articles/2018-10-25/merck- plans-10-billion-buyback-as-cancer-drug-tops-estimates. --------------------------------------------------------------------------- Your company recently spent $10 billion on stock buybacks.\22\ This year, will you commit to decreasing drug prices by that same amount? --------------------------------------------------------------------------- \22\ https://www.bloomberg.com/news/articles/2018-10-25/merck- plans-10-billion-buyback-as-cancer-drug-tops-estimates. --------------------------------------------------------------------------- Patient Stories: Stephen Hadfield from Charlotte, NC: ``I am on very expensive insulin for my diabetes. My Januvia is $400 a month and my Lantus is $350 every three weeks. If it was not for insurance, I would not be able to afford these drugs.'' Yvonne from Georgia: ``I can't afford the medicines I need to treat my diabetes. Januvia costs over $200, and with my other medications too I am in the donut hole, making it hard to manage my disease.'' Mark from Louisiana: ``I have extremely high cholesterol and I am allergic to statins. The only medication that I can take would be Zetia which costs $800 for 3 month supply after insurance coverage. The same drug is available in Canada for $150 for a 3 month supply and no insurance coverage!'' Johnson & Johnson About Johnson & Johnson: Since 2012, Johnson & Johnson has raised the price of its blockbuster drug Xarelto by 87 percent.\23\ In January of 2019, the company raised the price on about two dozen drugs.\24\ --------------------------------------------------------------------------- \23\ https://www.i-mak.org/wp-content/uploads/2018/08/I-MAK- Overpatented-Overpriced-Report.pdf. \24\ https://www.reuters.com/article/us-johnson-johnson- drugpricing/jj-raises-u-s-prices-on-around-two-dozen drugs- idUSKCN1P42VY. --------------------------------------------------------------------------- Questions: Will you commit to holding your price increases to inflation each year? Will you commit to striking a deal with the New York Drug Utilization Review Board if they deem it necessary to decrease the cost of Remicade for state taxpayers? Patient Stories: Sarah Pekarske from Texas: ``I have Lupus and I have had 3 blood clot episodes. I take Xarelto. In August of last year it was suddenly $100/month. It has cost $150/month since September! This is too expensive for me.'' Diane from Georgia: ``I have been on Remicade since 2013, but when I retire I won't be able to take it anymore because of change in insurance and higher co-pays. I don't know what I'll do.'' Patricia from Texas: ``I am on fixed income because I am disabled with rheumatoid arthritis. I need infusions for Simponi Aria I cannot afford. Even with help to pay for the infusion, my part is going to be over $500 per month. That is half of my income every month.'' Bristol-Myers Squibb Co. About Bristol-Myers Squibb: Over the last eight years, Bristol-Myers Squibb has spent over $25 million \25\ in lobbying expenditures and $1.75 million \26\ in campaign contributions, according to Open Secrets. The company raised the price of its blockbuster drug Eliquis by 6 percent \27\ in January 2019. Last year alone, U.S. Patients' paid Bristol-Myers Squibb $3.8 billion \28\ for Eliquis, a 30 percent \29\ year-over-year increase. --------------------------------------------------------------------------- \25\ https://www.opensecrets.org/orgs/ summary.php?id=D000000149&cycle=2018. \26\ https://www.opensecrets.org/orgs/ summary.php?id=D000000149&cycle=2018. \27\ https://www.foxbusiness.com/healthcare/meet-the-big-pharma- ceos-who-will-testify-in-the-senate. \28\ https://www.foxbusiness.com/healthcare/meet-the-big-pharma- ceos-who-will-testify-in-the-senate. \29\ https://www.foxbusiness.com/healthcare/meet-the-big-pharma- ceos-who-will-testify-in-the-senate. --------------------------------------------------------------------------- Questions: Will you commit to donating 50% less to candidates for public office in 2020 and investing that money toward research and development or decreasing price for patients? With your recent acquisition of Celgene, will you commit to ending Celgene's use of the REMS program to prevent a generic from coming to market for its blockbuster drug, Revlimid? Do you support the CREATES Act? Patient Stories: Elizabeth from New Jersey: ``The greed of Bristol-Myers-Squibb is horrible. Now I have to decide if I should just take asprin each day and hope I don't have a stroke or pay the high cost each month for Eliquis for $145 per month.'' Gail from Michigan: ``I didn't have coverage for a year and the Eliquis I need costs $400 per month. It's a crying shame that these drugs are so expensive. I had to stretch the script out by taking them every other day.'' Tara from Kansas: ``Drug prices are killing me faster than the disease. When I first started taking my blood thinner a few years ago, I thought $400 a month was terrible. Now, I wonder how I can possibly afford the next dose of Opdivo. I can't. Without it I die. With it I go broke. What kind of choice is that? No one should ever be put in this position. No one should make this choice ever.'' AstraZeneca About AstraZeneca: AstraZeneca has a history of charging cancer patients high prices. Here are three examples: Imfinzi costs $180,000 per year \30\ for lung cancer, Lynparza costs around $15,000 for 112 pills \31\ for ovarian cancer, and Iressa costs $8,000for 30 pills \32\ lung cancer. And before AstraZeneca faced a generic competitor for its high cholesterol drug, Crestor, the company raised prices multiple times, including by about 15 percent \33\ right before a generic competitor came to market. --------------------------------------------------------------------------- \30\ https://professionals.optumrx.com/content/dam/optum3/ professional-optumrx/news/rxnews/drug-approvals/ drugapprovals_imfinzi_2017-0502.pdf. \31\ https://www.goodrx.com/lynparza/medicare-coverage. \32\ https://www.goodrx.com/iressa. \33\ https://www.marketwatch.com/story/big-pharma-games-the-system- to-make-generic-drugs-more-expensive-2018-07-27. --------------------------------------------------------------------------- Question: Will you submit for the record the following information: the amount you have spent on research and development vs. AstraZeneca's yearly budget for marketing and advertising? Patient Stories: Teresa Bianco from Elyria, OH said: ``We have a family history of dangerously high cholesterol levels. My sister and I have been on every medicine out there. The only one that lowers us into the high 200's is Crestor. It is not covered by our insurances and thus is out of our reach. Sadly, we are both RNs and see others also go through this. We are college educated, helping people, always gainfully employed full time, but we are apparently disposable.'' Linda Schoene from Pikesville, MD said: ``I have GERD and am prescribed Nexium. On Medicare Part D, my copay is a little over $100 per month. I can't afford that. So I go without which causes me sharp pains in my stomach when I have a flair. I sometimes buy the over the counter version, but it is half the strength of what I am prescribed and doesn't treat my symptoms.'' Silvio from Pennsylvania: ``I was taking Crestor but the prices kept rising and because I am on Medicare I was not eligible for a discount. So I had to stop taking it. Next time I got a blood test my bad cholesterol skyrocketed.'' ______ Pharmaceutical Care Management Association 325 7th Street, NW, Suite 900 Washington, DC, 20004 Introduction The Pharmaceutical Care Management Association (PCMA) is the national association representing America's pharmacy benefit managers (PBMs), which administer prescription drug plans for more than 266 million Americans with health coverage provided through Fortune 500 employers, health insurers, labor unions, Medicare, Medicaid, and the Federal Employees Health Benefits Program (FEHBP). PBMs are the primary advocate for consumers and health plans in the fight to keep prescription drugs accessible and affordable. PBMs negotiate on behalf of consumers, and work to keep a lid on overall costs for prescription drugs with market-based tools that encourage competition among drug manufacturers and pharmacies, and incentivize consumers to take the most cost effective and clinically appropriate medication. By leveraging competition among manufacturers, PBMs save patients and health plans $123 per prescription, and will negotiate prescription drug costs down $654 billion over the ten years ending 2025.\1\ --------------------------------------------------------------------------- \1\ Visante, ``Pharmacy Benefit Managers (PBMs): Generating Savings for Plan Sponsors and Consumers,'' February 2016, https:// www.pcmanet.org/wp-content/uploads/2016/08/visante-pbm-savings-feb- 2016.pdf. PBMs manage Medicare Part D drug benefits through insurers, either as contractual service providers to stand-alone Prescription Drug Plans (PDPs) or Medicare Advantage plans that offer prescription drug --------------------------------------------------------------------------- coverage (MA-PDs). PBMs are proud of their performance in Part D. PBMs and Part D sponsors have kept overall program costs 30 percent below original government projections, offered beneficiaries lower-than-expected premiums, and generated high levels of generic utilization while providing broad choice of drugs and access to over 60,000 pharmacies, all while attaining a continually high rate of beneficiary satisfaction. PBMs Negotiate to Keep Drug Spending Manageable The most recent available data, which is for years 2016 and 2017, show that the overall growth in spending for all prescription drugs has been low.\2\ tallying 1.4% and -0.3% for 2016 and 2017, respectively. Drug industry stakeholders rightly trumpet such figures to show the success of private-sector negotiation in bringing spending discipline to the prescription drug market. --------------------------------------------------------------------------- \2\ KFF, ``What Are the Recent and Forecasted Trends in Prescription Drug Spending?'', February 20, 2019, https:// www.healthsystemtracker.org/chart-collection/recent-forecasted-trends- prescription-drug-spending/#item-start. However, the totals mask the dynamics at work in different sectors of the prescription drug market. Spending on generic drugs has actually been declining, while spending on brands has been increasing. According to a November 2018 analysis, for the previous year, spending on brands increased 4% while spending on generics decreased 3%.\3\ --------------------------------------------------------------------------- \3\ Blue Cross Blue Shield Association, ``Prescription Drug Cost Trend Update,'' November 14, 2018, https://www.bcbs.com/the-health-of- america/reports/prescription-drug-costs-trend-update. Further, the report indicates that while brand drugs made up only 17% of total prescriptions, they accounted for 79% of overall drug spending in the previous year.\4\ --------------------------------------------------------------------------- \4\ BCBSA, Op. Cit. Data underlying the overall spending figures shows that manufacturers have been increasing the prices they set for their drugs rapidly. According to IQVIA data, for the 5-year period ending 2017, brand invoice price grew at an average annual rate of 10.5%, while overall inflation in the economy, as measured by CPI-U, grew at an average annual rate of 1.3%.\5\ These trends are mirrored in a study conducted on drugs most used by the elderly. A 2018 AARP analysis found retail prices for 113 chronic-use brand name drugs on the market since at least 2006 increased cumulatively over 12 years by an average of 214 percent, compared with the cumulative general inflation rate of 25 percent from 2006 to 2017.\6\ --------------------------------------------------------------------------- \5\ https://www.iqvia.com/institute/reports/medicine-use-and- spending-in-the-us-review-of-2017-outlook-to-2022. \6\ AARP, ``No End in Sight for Skyrocketing Prescription Drug Prices,'' September 26, 2018. The near-flat overall trend for spending on all drugs, despite rising prices and spending for brands, illustrates the work that PBMs do as advocates for patients and their client health plans to hold the line on prescription drug costs. Drug Manufacturers Alone Set and Raise Prescription Drug Prices As the Committee continues its work with respect to prescription drug costs, one thing is clear: only manufacturers have the power to set or change prices. In recent years, brand manufacturers and their allies have attempted to deflect blame for the prices they set by blaming other parties in the drug supply chain,\7\ including pharmacies, PBMs, and wholesalers. While much has been said and written, research studies show that there is no correlation between the prices manufacturers set and the rebates PBMs negotiate with manufacturers. --------------------------------------------------------------------------- \7\ See, e.g., https://www.phrma.org/press-release/new-report- shows-how-supply-chain-shapes-brand-name-medicine-prices. A 2018 study found no correlation between the prices that brand drug manufacturers set for individual drugs and the rebates that they negotiate with PBMs on those products (see chart below).\8\ The data in the scatter plot below show that increasing list prices over a 5-year period were not correlated with changes in rebates (R\2\=0.016), as shown with the horizontal blue line. Additionally, there are prominent cases of higher-than-average price increases on brand drugs where rebates stayed the same or declined (e.g., Humulin). --------------------------------------------------------------------------- \8\ Visante, ``Increasing Prices Set by Drugmakers Not Correlated With Rebates: An Analysis Prepared by Visante on Behalf of PCMA,'' June 2017. [GRAPHIC(S) NOT AVAILABLE IN TIFF FORMAT] At the same time, separate research confirmed that negotiated rebates are correlated with competition-that the size of drug rebates is positively correlated with the extent to which a given brand drug faces competition in the market.\9\ --------------------------------------------------------------------------- \9\ Credit Suisse Equity Research, ``Global Pharma and Biotech,'' April 18, 2017. Other research sponsored in part by a multinational brand drug manufacturing firm reports that, for every $100 spent in the drug supply chain on branded drugs, manufacturers capture $58. This contrasts sharply with the amounts captured by pharmacies ($3), PBMs ($2), and wholesalers ($1).\10\ These results show that it is the manufacturers who benefit far more than any other party in the drug supply chain, and any rhetoric to the contrary is a smokescreen. --------------------------------------------------------------------------- \10\ Sood, N. et al. ``The Flow of Money Through the Pharmaceutical Distribution System,'' University of Southern California, Leonard D. Schaeffer Center for Health Policy and Economics, June 2017, https:// healthpolicy.usc.edu/wp-content/uploads/2017/06/USC_Flow-of-Money WhitePaper_Final_Spreads.pdf. Further illustrating the lack of any connection of manufacturer list prices to negotiated rebates is the chart below containing Part B pricing data. Drugs under Medicare Part B typically carry no rebates. The chart shows that several unrebated branded drugs have posted price increases vastly outpacing the rate of inflation, as well as the rate of price increases among most drugs. Moreover, unrebated drugs in Medicare are not unique to Part B--HHS's Office of the Inspector General finds a full 39% of branded drugs in Part D carry no rebatex.\11\ --------------------------------------------------------------------------- \11\ HHS Office of the Inspector General, ``Increases in Reimbursement for Brand-Name Drugs in Part D,'' June 2018. Selected Part B Drugs With High Price Increases From 2017 to 2018 ---------------------------------------------------------------------------------------------------------------- Estimated Estimatied 2012 Price 2017 Price % Price 2018 Price % Price Brand Name per Part B per Part B Increase per Part B Increase Prescription Prescription* 2012-17 Prescription 2012-17 ---------------------------------------------------------------------------------------------------------------- Miacalcin $461 $16,375 3,449% $19,266 18% Krystexxa $2,717 $19,163 605% $21,127 10% Teflaro $110 $399 263% $439 10% Bicillin $41 $106 159% $120 13% Rituxan $5,125 $6,890 34% $7,416 8% Orencia $1,636 $2,849 74% $3,020 6% ---------------------------------------------------------------------------------------------------------------- * Estimated inflation adjusted price = 2012 price * weighted average manufacturer increase in list price per unit. Not affected by changes in numbers of units per claim, or mix of doses/dosage forms. Estimated 2018 price through Q3 2018. During study years PBMs were not involved in Medicare Part B program, so no PBM rebates were involved. Analysis included drugs with Part B spending data for full period 2012-16. Source: Visante and PCMA analysis of data from CMS and SSR Health, 2019. In sum, the research record is clear: drug manufacturers alone are responsible for the prices they set and neither PBM-negotiated rebates, nor any other party nor factor in the supply chain affects the list price of a brand drug. Managing Drug Cost Growth Is Challenging, but Policy Changes Could Improve Competition PBMs have an established record of negotiating with manufacturers and pharmacies to reduce costs for patients, either in the form of lower premiums for all participants in a plan, or through lower costs at the pharmacy, and usually both. The key to reducing prescription drug costs is increasing and encouraging competition. PBMs are best able to negotiate when competition exists, and PCMA's member companies support a number of ideas for increasing competition and building upon market-based tools to improve the Part D program. These include: Remove Part D's protected classes. Designating ``classes of clinical concern'' where all or substantially all drugs in a class must be covered allows drug manufacturers to virtually name their price. Indeed, a recent Milliman analysis showed that the average brand rebate (for drugs that had any rebate) in Part D was 30%, while the average rebate for brand drugs in protected classes was 14%.\12\ CMS already applies careful plan formulary coverage checks to assure proper coverage. A pending CMS plan only to lessen the effect of protected classes-not eliminate them-would save $2 billion over 10 years. --------------------------------------------------------------------------- \12\ Milliman, ``Prescription Drug Rebates and Part D Drug Costs: Analysis of Historical Medicare Part D Drug Prices and Manufacturer Rebates,'' July 16, 2018, https://www.ahip.org/wp-content/uploads/2018/ 07/AHIP-Part-D-Rebates-20180716.pdf. Encourage greater use of generics for Part D LIS enrollees. MedPAC recommended allowing the Secretary to lower cost-sharing on generics and raise it for brands that have generic competition. Allowing plans to lower generic cost-sharing for these beneficiaries would save money for beneficiaries, taxpayers, and the Medicare --------------------------------------------------------------------------- program. Modify the requirement for two drugs per class. The requirement that Part D plans cover two drugs per class is outmoded. It has encouraged manufacturers to argue for ever more granular classes and reduced competition, increasing Part D costs. Modifying the requirement by requiring plans to ensure access to therapies based on conditions or disease states instead would reduce costs without reducing access to needed drugs. Build on existing efforts to apply Part D management tools to Part B drugs. PBM tools such as value-based formularies, manufacturer negotiation, and prior authorization have proven indispensable for improving patient safety and lowering costs in outpatient prescription drug plans like Part D. Adding Part D management tools to the Medicare fee-for-service program and building on efforts in Medicare Advantage for Part B drugs would make drugs more affordable on Medicare's medical side. Encourage use of mail-order pharmacy in Part D. Mail-order pharmacy: vastly reduces errors in dispensing; increases convenience for beneficiaries on maintenance medications; improves adherence; and offers a lower cost-sharing option to beneficiaries in most cases. With much of the public using home- delivery for a wide range of goods and with many Medicare beneficiaries home-bound, CMS should take further steps to encourage home delivery of maintenance medications. Repeal any willing pharmacy provisions. Requirements that all pharmacies be included in Part D networks drives up costs and are unnecessary, given the network adequacy requirements. Congress should repeal the provision. One study showed that greater use of limited network pharmacies in Part D could generate $35 billion in savings over 10 years.\13\ --------------------------------------------------------------------------- \13\ Visante, ``How Pharmacy Networks Could Save Medicare, Medicaid, and Commercial Payers $115 Billion,'' January 2013, https:// www.pcmanet.org/wp-content/uploads/2016/10/visante-pcma-pharmacy- networks-study-1-13.pdf. Give Part D plans meaningful access to Part A and B claims data. To coordinate care and make the best coverage decisions for beneficiaries, plans need to be able to use medical data as well as Rx data. Existing prohibitions on using A and B data to inform coverage design and decisions are misguided and keep plans from using claims data to improve care coordination and coverage. Researchers suggest combined data sets of Parts A, B, and D claims can be a ``rich --------------------------------------------------------------------------- resource'' for comparative effectiveness data. The following list of additional solutions would further increase competition in the marketplace. While these proposals are outside the Finance Committee's jurisdiction, they should help to bring balance back to the drug marketplace and enhance competition. Eliminate use of Risk Evaluation and Mitigation Strategies (REMS) to delay competition. Some manufacturers have used REMS to prevent generic or biosimilar developers from getting sufficient quantities of a drug or biologic to develop a competitor to the innovator product. REMS were never intended for this purpose; this practice should be prohibited. S. 340, ``Creating and Restoring Equal Access to Equivalent Samples Act of 2019'' or the ``CREATES Act of 2019'' would address these abuses. Stop anticompetitive product adjustments, i.e., ``evergreening.'' Drug manufacturers sometimes use tactics such as ``product hopping'' or ``evergreening,'' submitting applications to the FDA for approval of a ``new'' product that is essentially the same as the original product. These product lifecycle management tactics artificially extend drug exclusivity periods and delay the take-up of lower-cost generics. End orphan drug exclusivity abuses. Orphan drug exclusivities are meant to encourage research on rare diseases, but manufacturers have gamed the policy to apply it to blockbuster drugs with script volume in the tens of millions. Orphan exclusivity periods should only apply to those drugs originally approved by FDA under an orphan indication and only for the orphan indication itself. Eliminate ``pay-for-delay'' agreements. Patent settlements, or ``pay-for- delay'' agreements, allow drug patent holders to pay off potential competitors who would otherwise produce a competing generic or biosimilar drug. These anticompetitive agreements should be eliminated. S. 64, The Preserve Access to Affordable Generics and Biosimilars Act, would greatly ameliorate these concerns. Allow for FDA accelerated approval of brand drugs based on increasing competition. Accelerated review is granted to new drug applications that address ``unmet need.'' The economic need for competition to lower prices, or what some call ``financial toxicity,'' should be a criterion of unmet need. Revisit and improve biosimilar labeling and naming. Substitutable biosimilars should bear identical names and labels to their innovator analogs. Use of different names will confuse patients and providers and inhibit prescribing of biosimilars. Reduce innovator biologic exclusivity to 7 years. Seven years of data exclusivity would still provide a sufficient return to manufacturers, while also speeding more affordable biosimilars to market. These policies and some of the specific bills that contain them can help lower costs in Part D and the wider prescription drug market. Part D Should Work for All Enrollees, but the Administration's Proposed Rule Ending Drug Rebates Is Counterproductive In addition to the suggested policy changes above, specific interventions to help Part D beneficiaries who have high out-of-pocket spending are needed. Fourteen years into the program, it remains a great success with high enrollee satisfaction, however, policymakers should consider how best to balance the needs of all Part D enrollees. With respect to the Administration's recently proposed rule to end the drug rebate safe harbor, there is grave concern that this proposed rule would increase premiums for Medicare beneficiaries and costs for taxpayers. While the Administration's goals are well intentioned, the proposed rule does nothing to reduce the prices drug manufacturers set. To the contrary, it would cause substantial increases in seniors' Part D premiums, as well as the cost to taxpayers. The Administration's proposal also includes an unprecedented six different cost impact estimates by three different actuarial groups, including the independent HHS Office of the Actuary (OACT). The range of impact for cost to the federal government across the six estimates is an immense $300 billion. The great uncertainty surrounding the proposal should give the Committee pause. Americans deserve clarity on how such a proposal will affect those who rely on Medicare and Medicaid, and commercial coverage. Given OACT's skill and institutional independence from the agency, it is likely they have the most accurate estimates. Under the Administration's proposal, according to OACT, Part D premiums could rise by as much as 25 percent for 2020 to reach $47.66, marking the largest average premium increase in the program's history. Such a large increase could cause many seniors and disabled Americans to drop the prescription drug coverage they need to protect their health and financial security, or never sign up in the first place. Healthier beneficiaries (i.e., those who need fewer drugs) would drop coverage first, causing premiums to increase further and potentially destabilizing the Part D program, as increasingly those eligible for enrollment would find Part D coverage unaffordable. Additionally, OACT estimates that the proposal would cost the federal government an extra $196 billion over the next 10 years. If finalized, this could make the proposed rule among the costliest in U.S. history.\14\ --------------------------------------------------------------------------- \14\ American Action Forum, ``Mandating Talking Cars: Costliest and Most Beneficial?'', December 16, 2016. This article describes what were at the time, the two costliest proposed regulations in U.S. history. The OACT cost estimate for the Administration's proposal is in excess of these two, https://www.americanactionforum.org/regulation-review/ mandating-talking-cars-costliest-beneficial/. PCMA urges the Committee to encourage the Administration to withdraw, or at the very least significantly delay the implementation of, the proposed rule until its impact on beneficiaries and on Part D can be better understood and managed. Conclusion In the search for solutions to address high drug costs, the Committee and Congress would be best served in pursuing policies that foster and encourage competition to keep prescription drug costs and pharmacy benefits more affordable for employers, enrollees, taxpayers, and government programs. Unfortunately, the rule recently proposed by the Administration will not accomplish this goal, since it does nothing to encourage manufacturers to bring down the drug prices they alone set. PCMA member companies welcome continuing discussion among all stakeholders to create a robust, sustainable market that will continue to deliver needed cures and treatments for patients who suffer through disease and chronic illness. ______ Letter Submitted by Debra L. Raffle February 27, 2019 U.S. Senate Committee on Finance Dirksen Senate Office Bldg. Washington, DC 20510-6200 RE: The Escalating and Unsustainable Rising Cost of Insulin for Insulin-Dependent Diabetics Chairman Grassley and the Committee: I hope I am not too late and will be read at least. I only received this notification a few days ago from the American Diabetes Association, but I see you continue to have hearings, so I am revising and resending my letter. I have type 1 diabetes. I am an insulin-dependent diabetic, which means there's not one hour of every single day of my life that I MUST have insulin, or I will die. It's that simple. I was diagnosed around 9-11, sadly that it makes it easy to remember. I was an adult diagnosed with a mostly childhood disease and had a lot to learn! The cost of insulin that I need to stay alive 24 hours a day has escalated from $70 per 1000 ml vial to nearly $300 a bottle. The same bottle of Novolog sells for $47.99 in Canada. I just had to pay $2300 out of pocket for 3 months of insulin (and that was with a supposed discount)! The insurance I have through my employer has an extremely high deductible and high copays and some items are not covered at all. If my insulin pump supplies are not covered, I simply cannot afford them. If I can't afford to manage my diabetes the way my doctor and I have been doing successfully through pump therapy all these years, I will likely get sick, get a complication or two and then die. And no one seems to care! Certainly not the insurance companies or the pharmacies. People need to care. It will cost far more with the complications that will arise if I don't get my insulin and if I can't afford to pay it, other tax payers will ultimately bear those costs when all of this can be avoided. Again, I feel that most insurance companies and certainly the pharmacies prefer their profits over actual health care and effective management and if we can't afford the astronomical prices they are putting on once affordable drugs and supplies, then they would prefer we die and let someone else pay. This is insane to me! I should be able to afford my insulin and pump supplies, as in the past, but due to escalating prices of medications, insulin and insurance costs (so they can all make their profits) it is becoming unsustainable. I can't afford it and am very healthy and have a good paying job. I would like to join in the battle to fight insurance companies who seem to think we can do without these drugs--insulin is not even a drug, it's something my body quit making almost 20 years ago and that most of you all take for granted, but without it, I will, in fact, die within a few days/possibly lingering a few weeks in a coma. I didn't ask for this, however, if I am able to get what I need, what my doctor prescribes for me and have that covered by my insurance, I remain healthy. I am a working, productive, tax paying citizen and if you allow me to get insulin and medical supplies at a sustainable price, I can continue to be a productive tax paying citizen. If you don't I become unable to work, pay taxes and get sicker and die. Diabetes is a completely manageable disease and it's disheartening that the insurance companies, the pharmacies and the United States Government seem to have such low regard for those of us who were unfortunate to contract a disease where we have NO OPTION but to buy insulin at escalating prices. They keep raising the price of insulin higher and higher and higher, because they have a captive audience they are holding hostage. I really wish someone would take a stand on this and I would be willing to help, testify, or whatever it takes to help this situation. In addition, I also take a medication called Symlin that allows me to utilize my insulin more efficiently. It decreases my insulin intake about 30%. This helps me maintain a healthy weight. More insulin means more weight and more weight means taking more insulin. It's a vicious circle. I am a type 1 so I have never been over weight and I struggle to maintain my weight for the reasons I have listed above. If I can maintain my weight, not only will I be healthier, but I can take slightly less insulin to help combat the astronomical cost of something that I MUST HAVE EVERY SINGLE DAY OF MY LIFE. By reducing my intake by 10 units a day, I may get another day or two out each vial and that's a lot! It certainly will NOT help my overall health to put on extra pounds! Anyhow, my new insurance will not cover Symlin at all and they tell me it will cost $5800 for a 3 month's supply that I used to pay $70 co-pay when I had Premera. I have been on this drug about 10 years. This is ridiculous and clearly, I cannot afford this, so I get to go off it cold turkey, increase my insulin intake and pay more than I ever have for the same insulin! I don't think they understand how this all works nor do insurance companies and administrators care, but if you give us the tools (medications and supplies) to manage our diseases with, we will not have as many costly complications. So, it is cost-effective to give us what we need now to avoid higher costs of complications later! To date, since I was diagnosed as a type 1 in 2001 and having been on an insulin pump for 17-18 years, I have never had any complications due to my diabetes and would like to keep it that way. I am so disgusted with insurance companies and I want to know what we can do to get things changed. Can I go up to Canada and purchase my insulin? Can I testify and be a witness? I am willing to do whatever I can to help! What can I do to lower my medication and durable medical equipment costs? The insurance company cannot even tell me what things cost until I purchase them, which is ridiculous since I don't want to pay for things I clearly cannot afford. I'm lost and feeling desperate. I look to your committee to make this manageable disease financially manageable. It is manageable if we can afford what we need to survive and there's NO reason for the price to quadruple in the last 10 years, NONE except for greed and profits. I spent over $6.5K last year on out pocket medical costs, mostly insulin and pump supplies. I had no surgeries, I had no illnesses, I had no procedures. This is becoming very difficult to afford. I don't think I should have to struggle to afford groceries and lose my home or just make simple choices because I can't afford my insulin and supplies. Please do something about the escalating cost of health care, specifically common insulin, Novolog in my case, and do what you have promised for many years! This is unsustainable as it currently is! Thank you for listening. Debra L. Raffle ______ Letter Submitted by Laura T. Ricci March 4, 2019 U.S. Senate Committee on Finance Dirksen Senate Office Building Washington, DC 20510-6200 RE: February 26, 2019, ``Drug Pricing in America: A Prescription for Change, Part II'' To the Senate Committee on Finance, Thank you for beginning to tackle the outrageous prices of prescription drugs in America. I've watched many of the meetings and also the Congressional Oversight meeting with Congressman Cummings. I watched this meeting again and took notes. What I find interesting is several of the ``Magnificent Seven'' are foreigners. These are CEOs that have come to America to use Americans and the American healthcare system as pawns for their profits. I do think that it is a multi-layered problem and the American healthcare system is to blame for a lot of it. The first thing that the senate and congress need to do is regulate this industry so these people have to abide by stricter laws. All of the levels need to abide by stricter laws. I come to you as a mother of a type 1 diabetic, 20 years old, who will soon be on his own. What will happen to him if he has to enter a high deductible healthcare plan one day? Will he be the next Alec Smith or Antavia Worsham? I would like to see this system fixed before he has to cross that road. I am lucky enough to live in the Commonwealth of Massachusetts, where he is eligible for Masshealth benefits so I am not taxed in my wallet for his insulin. But one day, under the current system, he may be. What if he ever wants to move out of Massachusetts? What kind of healthcare plan will he be forced into? The current system is designed for failure for a T1 diabetic. The only way T1s can get their insulin for free or cheap is to make less than $16,000 or just work a part-time job so you will qualify financially. What kind of contribution to society is that? Will he ever be able to use the college degree he will earn? He might end up living at home for the rest of his life to be able to afford insulin because he will never be able to afford $324.00 for a bottle of insulin or the ridiculous copays assessed and high deductibles. High deductible healthcare plans need to be abolished. High deductible healthcare plans are only for the really healthy, they're not for anyone who needs to use the system, the only system in place. T1s are forced to use the system because insulin is not available over the counter like a loaf of bread is. My son can't buy and eat the bread if he doesn't have the insulin to go with it. Why does America not allow insulin to be purchased over the counter without a prescription? Why does America not trust Americans to use insulin correctly? I want insulin to be able to be purchased over the counter, maybe with a prescription, but no insurance attached to it. When you look at the supply chain of food, there's a manufacturer, a warehouse and distributor, the supermarket and then the consumer. When you look at the supply chain of medicine, there's the manufacturer, the warehouse and distributor, the pharmacy (supermarket), the consumer and then the PBMS and insurance companies. If the PBMS and insurance companies were eliminated from this chain, then the prices would come down because there would be no clawbacks and rebates involved. Is there a rebate for bread? No. My son was diagnosed with T1 diabetes in 2007. I was looking at some of my old receipts. I looked at one from 2010. The price that Blue Cross paid was $390.13 for 6 bottles of humalog. I had a $60 copay. That was $75.00 a bottle, but I only paid $10.00 a bottle with the copay. The lantus insulin was $152.48 that the insurance paid, and I paid $60.00. I got 3 bottles. So that was $212.48 divided by 3 is $70.82. I paid $20.00 for each bottle with the $60.00 copay. Today, I see the receipt from Walgreen's, and the cash price is $974.89 for 3 bottles of humalog. That's $324.96 each. That is what the Commonwealth of Massachusetts must pay because he is covered under Masshealth. Does Massachusetts pay that much? I have a feeling they do because Medicaid is not allowed to negotiate prices with drug companies. The budget for Massachusetts is 40% healthcare. Former Gov. Mitt Romney put this mandatory healthcare in place. This should have been used as the template for the ACA. Did the ACA cause these high deductible healthcare plans? Some people think it did. That's a question I have for you. Did the ACA cause high deductible plans? High deductible plans are bankrupting Americans. They're causing people to have to pay upwards to $25,000.00 sometimes for drug coverage before insurance will pay anything. It's unaffordable. People are selling their houses, taking out second and third mortgages, moving back home with mom and dad, and even living on the streets. You've heard the stories about people rationing insulin and dying. I don't want that to happen to my son. T1 diabetes will never go away. There is no cure. The pharmaceutical companies know there is no cure and know we are at their mercy. The American lawmakers allow them to carry on. You need to regulate this industry and put the brakes on their practices. Utilities, food, tobacco, guns, are all regulated. It's time for pharmaceutical companies to be held accountable so they will stop using Americans as pawns for profit. As said in the hearing, they make money on their drugs in Germany. If they didn't, they would say goodbye to Germany. When people can go to Mexico and buy the insulin for $30.00 a bottle, Canada for $35-45.00 a bottle, then that tells you that the price to produce it is low. I read an article that showed a study that said it only costs $3-6.00 to produce a bottle of insulin. It's just like the EpiPen. Heather Bresch, the CEO of Mylan, she told the Senate that it costs Mylan $1.00 to make it, they sell it for $60.00 and it retailed for $300.00! That's nuts. A lot of EpiPens never even get used. They're there for an emergency. Insulin is used anywhere from 4-10 times a day because you need to take it every time you eat. You don't need an EpiPen every time you eat. The equivalent to an EpiPen for a diabetic is a device called a glucagon injection. It is also very expensive and is often never used. It's an injection that will revive you from a low blood sugar if you pass out and may have a seizure. According to GoodRX website, the glucagon retails for $292.81 which is 19% off the retail price of $364.50. This is another device that often goes unused, but people pay for it because they want it in case of emergency. There are no coupons available to get it for free. I would like to know how much it really costs to manufacture a glucagon kit. The other thing that people are doing to get insulin is they're taking out gofundme accounts. They try to raise money to pay for the copays. They don't always succeed in raising the money and still end up dead, which is the case with a man named Shane Patrick Boyle. People then have to take out gofundme accounts to bury their loved ones because once you are diagnosed with T1 diabetes, you have a lot of difficulty in getting life insurance. You're a threat to insurance companies. They only want to bring money in, they don't want to pay it out. But they pay it out to CEOs in the form of huge salaries. All of the CEOs at every level of the supply chain make a lot of money. David Ricks, CEO of Eli Lilly, he makes $40,000.00 a day in salary. $5,000.00 an hour. Some people don't make $40K in two years. The CEOs of CVS, Walgreen's, Rite Aid, Kroger and all the insurance companies, like United Healthcare and Blue Cross, they also make millions. Why? Why is that allowed? They've all created monopolies. I've watched their stocks and they've all skyrocketed and I see a new CVS store in many towns around where I live. They've closed the old stores and built these fancy new buildings that are full of expensive products. I only get my son's insulin at Walgreen's because I am forced to get it locally, Medicaid will not allow you to use a 90 day pharmacy service. And insulin isn't the only thing that diabetics need to use for daily management of diabetes. They need test strips, meters, pump supplies, Dexcom supplies, glucose tablet s, ketone test strips, alcohol wipes, and sometimes they have to eat special food if they also end up with Celiac Disease. There are at least 80 autoimmune diseases. There is no cure for any of them. Do you think the pharmaceutical companies think there is a cure on the horizon, a vaccine? Is that why they're raping American's to get their profits before people don't need insulin anymore? Nicole Smith-Holt, the mother from Minnesota that lost her son Alec to rationing insulin said this in a Minnesota Roundtable: ``Before insulin was invented, diabetes was a death sentence. Now diabetes is a death sentence again because insulin is no longer affordable.'' Let that sit with you. I have a change.org petition going around asking Congress to subpoena the CEOs of the insulin companies. One of the signers of the petition posted that this is the new AMERICAN GENOCIDE. Let that sit with you. I like what Senator Wyden said about these CEOs using patients and taxpayers as ``unlocked ATMS.'' It's the truth. I also like what he said when he said ``drug prices are astronomically high because that's where pharmaceutical companies and investors want them, and diabetics who can't afford the costs self-ration and endanger their lives but the investor s are happy.'' It's the truth. The CEOs were asked `'What keeps you up at night?'' None of them answered that they were concerned about anyone dying because they can't afford their medicines. They all answered that they were more concerned about their drugs being put on formularies. That brings me to another problem. The formularies. The PBMS play games all the time with the switching in and out of the type of insulin that the insurance company will pay for. This means that people often end up getting a physician's override to be able to continue using the insulin of their choice. The formulary dictates to the diabetic what they can and cannot use. They limit your choices or make you fight for the kind of insulin you want to use. Do you have the choice to buy Pepperidge Farm bread or store brand bread? Yes. So why doesn't the diabetic or person in need of medication, have the ability to choose the one that works right for them and not have to argue and fight for it? If the industry was regulated, we may have the ability to choose what is right for us, the patient and consumer. Another problem I see and have stated this before, is that Congress has to pass legislation stopping these pharmaceutical companies from advertising on TV. They did it with tobacco. The last advertisement for tobacco was for a Virginia Slims ad on December 31, 1970 on the Johnny Carson show. Congress did that. So they need to do it again for pharmaceutical. American and New Zealand are the only countries that allow them to spend their profits on advertising. If they want to advertise, they should only be able to advertise for medicines that don't require a prescription. And I'm also tired of seeing advertisements on TV for erectile dysfunction. Doctors: Doctors need to inform patients of alternatives to getting insulin and not having to use insurance. People are already buying insulin from Canadian Pharmacies and going to Mexico if they can. The State of Utah will actually pay their state employees $500.00 to cross the Mexican border and get their medicines there instead of having to put the burden on the state's budget to pay for expensive medicines in the U.S. Isn't that crazy? Why should that happen? If medicines were affordable, the drug companies wouldn't have to give so much away for free. The burden would be shared equally and the money would stay in America. And I don't buy the insulin companies' stories about the fact that the insulin supply chain is not protected in Mexico like it is in the U.S. If the insulin in Mexico were tainted, people would be dying from it and it would be in the news that people are dying from it there, and dying in foreign countries from it. So that is just a scare tactic to get you to continue to pay high prices to support the high CEO salaries. Soriot--He said he was annoyed that he was the lowest paid CEO. Give me a break. That is all part of the GREED before NEED and PROFITS before PATIENTS. The FDA--Mr. Gottlieb, the commissioner, he is a part of the problem behind insulin as well. Insulin was classified as a DRUG. He went and changed the classification to a BIOLOGIC. That's just a term for a liquid medicine. So then that created the new biosimilar insulins. After thinking about this, I figured out that the biosimilars didn't make insulin a generic, all it did was allow these insulin companies to take out new patents, patents that will have maybe a 20 year life span under the Hatch-Waxman Act. So what does that do? It creates even more of a monopoly. Why, after almost 100 years, is there no generic insulin available? No one has an answer to that. The patent for humalog is long since expired. All these insulin companies have to do is tweak an amino acid in the insulin and they get a new patent. That's ridiculous to me. Today, March 4, 2019, there was a news article issued about Eli Lilly: https://investor.lilly.com/news-releases/news-release-details/lilly- introduce-lower-priced-insulin. In this article, Eli Lilly said they were going to make a ``generic'' humalog and the list price of it would be $137.35 for a vial and $265.20 for a box of 5 pens. That is ridiculous to me. First, how do we know that Eli Lilly won't just use the humalog as it is now and just put it in a new bottle with a different color and change the name on it? Are they only doing this to appease the senate and Ms. DeGette's investigation into these high prices? Plus, they already have their BLINK HEALTH system, which is like a GoodRX, that allows you to get a vial of insulin at $178.90 and if you don't have insurance, you can get insulin from GoodRX for $177.87. These prices are lower than the $324.00, but they still aren't the $30.00 or $45.00 that Mexicans and Canadians reap the benefits from. Canada would never allow insulin to be price gouged because it was invented there by Sir Frederick Banting who has probably rolled over in his grave a million times by now. I told my congressman, James McGovern, that insulin wasn't supposed to be a FOR-PROFIT business. He turned around to me, looked me in the eyes, and said: ``Well, it is''! The other thing about the financial aid that Eli Lilly offers, is you have to be really poor to be able to qualify for it. So only the poor, nonworking people in America can get it for free. They wouldn't have to give it out for free if it was affordable and accessible over the counter at the pharmacy. They also give a lot of insulin way to camps. Another thing that doctors don't tell people about is the 340B program. That's like a big secret, just like the other secrets that revolve around this industry. Many state attorney general's already have their own investigations going on to find out what is going on behind closed doors. What I heard from some of these CEOs, especially Caforio, was that they ``need America's help and support'' to fix this problem. I heard that from several of them. So they are asking YOU, the congress and the senate, those that write the laws, to help them figure it out because they know the system is unsustainable as it is and they will only continue to do what they are doing because there are no laws saying they can't do it. That's where my new hashtag comes into play-- #thepowerofthepen. Lawmakers are voted in with the power of the pen and lawmakers can pick up the pen and write laws to protect Americans from the greed of this industry. I write to my congressman, James McGovern, and my senator, Elizabeth Warren, and share with them what I am sharing with you. I share that they need to take action and write better laws and regulate this industry. They also have to stop taking money from the pharmaceutical companies and lobbyists and don't fall for their antics. These people are crooked and have the thief mentality. Mr. Frazier stated that he couldn't walk away from the U.K. even though they give lower prices because he believes it is immoral. But it's okay. that he price gouges Americans and that's not immoral? I read in a recent article about Mr. Brandicourt, that he fought to keep any generic insulins out of the market and actually took out more patents to prevent it. So why is that allowed? That's crookedness. That is another case of Greed before Need. Companies like his, Sanofi, they give out coupons for their lantus insulin. They wouldn't have to give out coupons for people to get it for cheap or free if they just lowered the prices and made them affordable. NovoNordisk also gives out coupons and the same applies to them. Why can they let you have insulin for $25.00 with the coupon, but you can't go to the pharmacy and get the insulin for $25.00 without the coupon? So you know the price to make insulin is cheap if they are able to give out coupons for you to get it for free or cheap. Senator Isakson, he had quite the story. He has Parkinson's disease and takes 8 medicines. His story about all the ways he could get his medicines for cheaper were right on target. The options: Don't use insurance, use coupons, get rebates or just pay CASH. People could just pay cash if they didn't have to pay and arm and a leg for medicines that are supposed to keep you alive, not kill you because you can't afford them. And his story about his staff member's 2nd child being diagnosed with T1 diabetes was heartbreaking. T1 diabetes is an epidemic. There is never anything shared on TV about the signs and symptoms of T1 diabetes. Kids die from it after being misdiagnosed with strep throat or the flu. T1 diabetes mimics the flu. My son had strep throat when he was diagnosed. And it's not caused by vaccines. T1 diabetes has been around for over 4500 years and no vaccines were invented then. People just died from it before insulin was invented in 1921. My personal story is this: I have epilepsy. I take 3 medications for it. One of them was invented in 1914. It's older than insulin. When my husband had a great job with great insurance, I paid $3.96 for a 90 day supply. When my husband lost his job, I was eligible to get on Medicare because I am on disability. When I went to get my medicine at the pharmacy, I was hit with a $114.41 bill. YIKES! This stuff is cheaper than aspirin and here I am paying $114.41. The Medicare system, the Part D, they put the medicine on the most expensive tier. So what am I supposed to do? I have to pay it or my head goes nuts. Another medicine I take, the patent doesn't expire until 2022, so there is no generic for it. I just had to pay $1,200.00 for this medicine at the beginning of the year. Ouch! My disability benefits are $1,600.00 a month. Do the math. I wish I had never started to take it. The next time I get the prescription filled, it will be $800.00 for it. I will never meet the deductible set on my Part D plan because it is set so high that I never reach it. So I pay over $300/year for my Part D plan, over 1,200.00/ year for my Part B, and even though the deductibles are lower than a high deductible plan like a Blue Cross plan, it still hurts the wallet every time I need to refill these prescriptions. I'd like to share with you some stories of people that have children with T1 diabetes. 1. This lady had a child die from T1 diabetes after the girl was kicked off of BCMH at the age of 21. The girl rationed her insulin and was found dead at home. The lady also has a second daughter that has T1 diabetes. She started a foundation and is on the warpath to make sure people don't die from insulin rationing and get kicked off of health plans. She just shared a story about her daughter being denied the Dexcom continuous glucose monitor. People like her are always fighting with insurance and distributors, especially Edgepark Medical Supply, to get their supplies. This is a problem created by insurance companies that ``don't want to pay.'' They will do everything in their power to deny you and now people are turning to Costco to get this Dexcom device and get out of the insurance loop to get it, and get it cheaper than it costs to use their insurance. Yet, these people are still paying their premiums and they can't use the insurance. 2. This lady and her son, they live in Tennessee. Tennessee, as I found out, is one of the states that did not adopt the Medicaid expansion. The son is 24 years old. He is a T1 diabetic as well. He was working at a Hardee's burger place. He lost his job after getting sick with diabeticketoacidosis (OKA). He was in the hospital and couldn't work so they fired him. He had no access to insulin and started taking the ``WALMART'' insulin. This isn't the right kind of insulin for a T1 diabetic to take. He ended up with a big sore on his arm from injecting the insulin in the same spot all the time. He ended up with a bad MRSA infection. He went to the hospital and was not taken care of very well and he checked himself out. He wanted something to drink and was denied water. The mother didn't know how to navigate the politics to get help in the state. She tried to get a social worker to get her son on Medicaid. She was told NO, that he didn't qualify because he wasn't pregnant, wasn't a single parent, and was over the age of 21. So the message from the state of Tennessee is ``JUST GO DIE'' if you can't work and get private insurance and you're over the age of 21. ``We don't want to take care of you anymore even though you have a life threatening disease.'' So I contacted the governor there and got his office to contact TennCare, the Medicaid office, and was able to at least get him set up to get insulin, but he still has no doctor to report to because he was denied care at a medical center there because he missed three appointments and they won't take him because of a long wait list. The option of moving out of the state is out of the question I was told. So here is a man that will end up living with his mother the rest of his life because he can't hold a job due to his diabetes. 3. A family from Texas. The father has a decent job but they live paycheck to paycheck. They also have a T1 diabetic child. The father was offered a TWENTY CENT raise. That means he would make $416.00 more per year. Guess what? The twenty cent raise put his family over the income qualifications to be able to continue to get CHIP benefits so they can afford the insulin for the diabetic. The family would be forced to take the insurance from the place of work. The insurance would cost them $400.00 per month out of their paycheck. That means they would lose $2.50 an hour if they took the twenty cent raise. Does that make sense to you? The father ended up signing a waiver and not accept the raise so he won't lose the CHIP benefits so he can keep his child alive and not have to go get another job or try to come up with the money for insulin one way or another? If insulin was affordable and accessible over the counter, the $416.00 a year raise might pay for it. But that's not the case. So much for a raise. I told the mother to tell the company to give him a gift card for $400.00 that she can use on groceries. 4. A United States citizen moved to the U.K. so she could get her insulin to stay alive. What in the world? Are you kidding me? Cases like this are what take money out of the U.S. economy. 5. A mother was on vacation, she only took one bottle of insulin with her. The insulin got dropped on the floor. She came running to Facebook to see if anyone could supply her with insulin because she couldn't get a hold of her doctor to see if she could get her prescription filled where she was. She couldn't just walk into any pharmacy and say she wanted to buy the insulin her child used. She could do that if she needed a bottle of water, but she can't do that with insulin. She was frantic, thinking, how am I going to keep my child alive? The pharmacist was not allowed to give her insulin without a prescription. There was no emergency system in place. The pharmacist had no authorization to give an emergency supply of insulin to this desperate mother. In the end, she was finally able to get her doctor to call her back and call in a prescription to the pharmacy to get a bottle of insulin. That should never happen in America. So I see people pay for premiums out of their paychecks, they pay for copays at the doctor's office, they pay outrageous amounts of money in high deductibles, and what do they end up with? They end up in debt, end up with their own health problems because they are going crazy wondering where in the world they are going to get this money from and not have to lose everything they have. Senator Stabenow was in a hearing that I watched and she actually said she took people over the border to Canada herself to get cheaper medicines. What does that tell you? That tells you that she's a great person that will do whatever she has to do to make sure people don't die at the hands of the current system. Our system is broken, it's old, it out of date, and I am not 100% sure if this is all because of the Affordable (Unaffordable) Care Act. I find that the people that make these laws are not the people that actually have children with life- threatening diseases and they have no idea what the cost of managing the diseases consists of. If America is going to allow the pharmaceutical industry to dictate to them how the system should be run, then that is the wrong way of doing business. I do think that the Senate Finance Committee and congress have to subpoena these other pharmaceutical CEOs and get them to answer and be transparent about how much it costs them to make their products. I have a change.org petition going around getting signatures to ask congress to subpoena them. You can't just invite them. An invitation can be ignored and turned down, but not a subpoena. Heather Bresch had to come to Washington to be transparent, so don't let the rest of them off the hook. Another thing about Eli Lilly: I read in the news that they were going to buy an $8Billion oncology company. If they have $8B to buy an oncology company, then why are they killing people with the high costs of insulin, literally killing people because they just can't afford their outrageous prices? They should not be able to buy a company like that until insulin is affordable and accessible to everyone, not just in America, but even in Africa. Why isn't insulin available in Africa? People die from having no access to insulin there as well. Diabetes is a global disease. You can't eradicate it. There is a genetic component to it. People are living longer now with the invention of insulin so they are passing the genes along to their offspring who ultimately pass it on to the next generation. March 5, 2019: This morning, as I continue to write and finish this, I see a news article about Senator Durbin's response to Eli Lilly's announcement yesterday. He acknowledges in there that insulin is as low as $38.00 in Canada, but charging Americans four times the amount of what Canadians pay it not an outpouring of gratitude. Canadians pay less because their government negotiates the prices with these insulin companies (http://www.kfvs12.com/2019/03/05/lawmaker-weighs- annoucement-by-drug-maker-sell-lower-cost-insulin/). When will the United States do the same thing? Why do you have to have a National Health Care system to do it? Just regulate the industry, like gas and electric, and start setting limits on the prices they can charge. And the article says that Senator Durbin is urging the FDA to approve lower cost drugs. There is no generic insulin. Why, after almost 100 years, is there no generic insulin? Generic insulin is not the solution to this dilemma. Just lower the cost. They've made their money over the years, the patent for humalog is long since expired. Like I said, Eli Lilly can just take humalog, stick it in a different bottle, relabel it, and tell you it's a generic. The FDA can't regulate prices. Let them be in charge of making sure drugs are safe, but don't leave them in charge of this. Mr. Gottlieb went and changed the category from a drug to a biologic--that didn't lower the price, it only created new patent s. If there was a regulated industry, the price would still be controlled on new patents. Recap: The drug industry needs to be regulated. These companies need to be saved from themselves. They don't know how to do it on their own. Insulin needs to be available over the counter without a prescription. (Kevin's Law has been passed in many states to authorize pharmacies to give an emergency, up to 30 day, supply of insulin and the pharmacy and insurance can catch up with paperwork afterwards.) The United States needs to trust citizens to use insulin correctly. It's available over the counter in Mexico. The United States needs to find out exactly how much it costs to make insulin. The U.S. found out how much it costs to make an epipen. PBMs need to be abolished. High deductible healthcare plans need to be abolished. If insulin is not accessible over the counter without a prescription, then it should be exempt from any and all deductibles on healthcare plans, as should any prescription medications. No diabetic in America should be denied healthcare (#medicare4all). People shouldn't have to take out gofundme accounts to raise money for their medicines. People shouldn't have to take out home equity loans and second mortgages to pay for their medicines. People shouldn't have to turn to the black market and Facebook to find insulin. People shouldn't have to go out of the country to get affordable insulin (#insulin4all). People shouldn't have to share insulin with family members. People shouldn't have to revert to using the ``WALMART'' insulin which is going to kill them if not used correctly. People shouldn't have to rely on coupons and scrounge around for ways to get discounts on insulin and other drugs. People shouldn't have to feel they are a burden to their family and ration insulin. Companies that price gouge should be held accountable, fined and sued so they will stop being so greedy. CEOs shouldn't be making so much money while people are dying. Insurance companies shouldn't be able to dictate which medicines and insulin they want us to use. We should be able to choose the one that works for us. That's how the PBMs work. They tell us which insulin they will pay for. If insulin was available over the counter, the PBMs wouldn't be able to dictate which kind of insulin I want to use, just like they can't decide what kind of bread I want to eat or if I want to buy Mobil or Shell gasoline for my car. The Hatch-Waxman Act is being abused. The V.A. can negotiate prices for drugs and medical care, but only Medicare Parts A and B can negotiate prices. Medicare part D needs to be able to negotiate prices in an unregulated industry. You have the power, use it. Insulin doesn't need new R&D. Using that as a reason for high prices is a bad excuse for high prices. Television ads for prescription drugs has to stop, just as tobacco ads stopped. Politicians have to stop taking money from big pharmaceuticals. The pharmaceutical companies are like the mafia. If financial aid is going to remain available, the income requirements need to be adjusted to keep up with inflation and keep up with the times. People that make a decent, living wage, should be able to get some relief if these high deductible plans continue to exist. If you just got rid of high deductibles and the prices got lowered, we wouldn't be talking about this. Be proactive, not reactive. Right now we are in a reactive position. A sick person will always use the system since most want to live. Those that don't want to live will commit suicide. More teaching needs to take place in our country on what Type 1 Diabetes really is. It is often mixed up with Type 2 diabetes. They are not the same disease. The PBMs need to be hired by the U.S. government to do the negotiating for lower prices, not be employees of the insurance companies. That creates a racket and secrets. Listen to more REAL stories of the burdens placed on Americans. Let the Americans tell you what they need and want, not allow the pharmaceutical companies to run their own agenda. Without sick people, they wouldn't even be in business. Put the brakes on big pharma. List prices work against the patient. Either set lower list prices or pass on the discounts to the patient. Patients don't care about pharmaceutical's position on the formularies, they care about being well. Stop the ``Happy Talk''; get down to business and pick up the pen (#thepowerofthepen). Lawmakers work for the citizens of the United States and get paid by our tax dollars. It's time for lawmakers to listen to citizens and not big pharma. Soriot's wise words: VBP--It used to be a system that was fit for purpose. Now it's no longer fit for purpose. No one in the system can fix it for themselves. The government has to step up and change the rules. #painpassionpurpose: Three words uttered to Nette Worsham by Congressman Cummings on January 29, 2019. CEOs from the two other insulin manufacturers, Eli Lilly and NovoNordisk need to be subpoenaed. They have been invited too many times and never accept the invite. Don't send letters asking for CEOs to tell you how much it costs them to make their drugs, make them come to Washington to tell you so the public can hear their lame excuses as well. Thank you, and I look forward to the next showdown with the PBMs and insurance companies. They are part of the problem, not part of the solution. The United States government is the entity that is part of the solution. Sincerely, Laura T. Ricci Statement of Rhonda Rowland R2 Communications, LLC Atlanta, GA March 5, 2019 U.S. Senate Committee on Finance Dirksen Senate Office Bldg. Washington, DC 20510-6200 To whom it may concern: This is in reference to the ``Drug Pricing in America: A Prescription for Change, Part II'' hearing held on February 26, 2019. As a person living with a rare disease and an advocate, I'm submitting the attached articles that provide background on the discovery/ development of two old, cheap drugs that pharma has raised prices on, and the impact on patients. Best regards, Rhonda Rowland R2 Communications, LLC [email protected] RhondaRowland.com 404-680-9053 High drug costs: the tale of 4 women In 2016, Berna Heyman testified before a U.S. Senate committee about her personal experience with sudden and dramatic increases in drug prices. She was forced to switch drugs to treat her chronic genetic disease, which was not the ideal option for her. ``The only reason I changed was the cost,'' Berna testified. Her health had been stable while taking the drug Syprine, which removes excess copper in people with Wilson disease (WD) to prevent potentially fatal poisoning. ``My doctor and I made the change only under duress.'' Valeant Pharmaceuticals (now Bausch Health) acquired the rights to Syprine in 2010 and began increasing the price. It's an old drug that was developed in the 1960s by British physician Dr. John Walshe, who made it in his laboratory and distributed it for free for many years. ``It was cheap to make,'' he told me. The generic name for it is trientine. As a librarian at the College of William and Mary in Virginia for 34 years, Berna had good health insurance and drug coverage. Her WD went undiagnosed for 60 years, making her one of the oldest patients to be diagnosed. The first sign of her disease was cirrhosis of the liver that was picked up incidentally by a radiologist. Upon retirement, she was insured through Medicare and supplementary insurance. ``By 2014 my projected co-pay exceeded $10,000 per year with my insurance paying over $260,000,'' Berna testified. ``That is untenable. Something has to be done.'' At the hearing, Valeant executives expressed regret and admitted to being too aggressive with their pricing strategies. When questioned by Senators, they said they'd lower their prices. For 3 years, Berna has waited. But Bausch Health has yet to lower prices. ``I left the hearing feeling hopeful, and anticipated changes by Valeant,'' Berna told me. ``It's very disappointing. It's the same old, same old.'' Therapist kept patients out of the system, but drug company put her in it Rose was completing her college degree in mechanical engineering when she noticed that she drooled while reading. Then she began forgetting math formulas, so she'd write them on her arm. As a straight-A student, she was bewildered that she had to re-read book chapters because she forgot what she'd read. She was on the crew team, but her fatigue got so bad that she couldn't keep up. ``I left college and went home,'' said Rose, who asked that her name be changed for privacy. After seeing more than a dozen doctors in New York and not getting a diagnosis, she went to an ophthalmologist who told her that some diseases can be diagnosed through the eye. He was right; an exam revealed Rose had rust-colored rings in her eyes, known as Kayser-Fleischer rings which are commonly seen in WD patients. Once diagnosed, Rose began taking the de-coppering drug, penicillamine. Her condition improved and she returned to college. But her WD left her with some memory loss and she couldn't remember her calculus formulas. She switched majors and got a degree in occupational therapy. Rose moved to Arizona and worked full-time as an occupational therapist for 20 years. ``Then one day I went to the pharmacy to pick up my WD drugs and was told my co-pay was $12,000! I was a single mom raising two kids and I couldn't afford it,'' said Rose. ``I felt totally screwed.'' She had been prescribed Cuprimine, the brand name version of penicillamine--also made by Bausch Health. Penicillamine was discovered in 1955, also by Dr. John Walshe. ``It's easy to make if you're a good chemist,'' Dr. Walshe told me. Rose tried zinc supplements, an inexpensive, alternate treatment for WD, but they made her violently ill. Without her daily dose of Cuprimine, her fatigue returned and depression set in. She could only work part-time, so she lost her health insurance. Her WD symptoms worsened, so she could no longer work and applied for disability benefits. ``As an occupational therapist I was contributing to the system, and keeping others out of the system,'' said Rose. ``Then the drug company put me into the system.'' Importing drugs from Canada and overseas After going without medication for months, Rose's uncle found a way for her to get affordable penicillamine through a Canadian pharmaceutical broker. At first, her supply came from England. ``The medicine looked and smelled like what I had taken for years, although the brands were different,'' said Rose. ``But then a shipment came from India that didn't smell right.'' She looked for another option and found Duane, a prescription drug broker in the Midwest who could get her drugs shipped directly from Australia. She needed a doctor's prescription and paid about $200 for a 3-month supply. ``We operate in a loophole,'' Duane said. ``Individuals are allowed to bring in a three-month supply of prescription drugs from other countries.'' What Duane told me is partly true: It's illegal for individuals to import prescription drugs in most circumstances, because the FDA can't ensure the drugs' safety. And anyone who facilitates the importation is also liable. But in reality, the FDA looks the other way. So, it's tempting to take the risk. Duane imports an AIDS medication for a client who had a $25,000 co-pay. ``I can get it for him for $1,200 a month.'' With exorbitant drug prices and patients' growing inability to pay them, there's momentum to make such drug imports legal. Five bills are before Congress that would allow prescription drug imports, primarily from Canada. Staying at poverty level to get prescription drugs Ashley Williams was about to start classes at Kansas State when she was diagnosed with WD and had to quit school to go to work instead. She was grateful to have a diagnosis for the hospitalizations and unnecessary surgeries she experienced the previous 2 years. ``I needed health insurance, so I took a full-time job with a technology company,'' said Ashley. ``I worked my way up from `coffee girl' to project manager and was working 70-80 hours a week.'' Even though she was taking Syprine, her health deteriorated. She thinks it was due to working too hard, to prove she wasn't sick. For medical reasons she got laid off and applied for disability benefits. Now with Medicare and supplemental insurance to cover her health care, she can't afford her Syprine co-pays. ``This year, I was told that the funds for Wilson disease were already gone!'' said Ashley. ``The $1,200 co-pay for my 30 days of trientine took my entire Social Security check.'' ``A health insurance broker advised me to look into the PAN Foundation,'' said Ashley. ``I qualified and get $10,000 a year to cover the cost of my co-pay.'' The Patient Access Network Foundation relies on donations to help people who are underinsured with medication costs. Patients have to reapply every January for the PAN Foundation's drug benefit. ``But this year, I was told that the funds for Wilson disease were already gone!'' said Ashley. ``The $1,200 co-pay for my 30 days of trientine took my entire Social Security check.'' Teva Pharmaceuticals introduced the first generic trientine in 2018 to compete with Bausch's Syprine. Generic competition hasn't lowered the drug cost . . . yet Dawn, who was diagnosed with WD at age 37 after her liver failed, was shocked when she picked up her prescription for trientine in January. The list price was $38,365.09. Her insurance co-pay was only $15. Still, she's not taking her good fortune for granted, and is stockpiling her drugs. ``I'm scared to take them all,'' said Dawn, who asked that her real name not be used. ``I went without my drugs for 3 years because we couldn't pay for them when the costs spiked.'' Ultimately, the drug saved her life. But they went bankrupt in the process. Her husband had taken a new job just before she was diagnosed with WD. And then, just as their new insurance was coming through, ``the suckers fired him,'' Dawn says. ``They knew I needed a liver transplant and was really sick.'' She had no choice but to take Syprine, and ultimately, the drug saved her life. But they went bankrupt in the process. Bausch currently offers patient assistance programs to insured and uninsured WD patients in the US who need Syprine or Cuprimine. ``Our first priority is that every patient has access to the medicines they need,'' a Bausch Health spokesperson said in a statement. Dawn tried to get help from the drug company previously, but couldn't. The inexpensive alternative, zinc therapy, made her sick. Her husband eventually found a job that provided health insurance--700 miles from their home, in another state. ``He works 70 hours a week hauling chemicals in extreme weather on treacherous roads. It aged him so much.'' Dawn's liver healed enough so she could be taken off the transplant list. Still, she's furious with the drug company for making the drug's cost out of reach for 3 years. And, she's fearful it could happen again. How does the tale end for the 4 women? Berna Heyman is encouraged that the problem of high drugs costs is still a major discussion. ``That's the bright side,'' she said. However, since she was forced to switch her WD medication, tests show copper has reaccumulated in her liver. Her doctor advised a low-copper diet for several months, but that didn't help. ``I may have to start taking trientine again.'' Rose credits Duane for saving her life with the drug imports. But fear of her supply line drying up led her to enroll in a clinical trial testing a new drug for Wilson disease so she can get her life-saving medication at no cost for the next five years. ``I hope the new drug works,'' she said. Fear over the uncertainty of being able to pay for her drugs also led Ashley Williams to enroll in the new WD drug trial. By chance, she was put in the ``standard of care'' arm of the trial. That means she continued on trientine for a year and paid the drug's cost. ``Starting in April, I will be taking the new study drug,'' she said. That means she pays the $1,200 co-pay for her trientine for another month. ``It's scary to think that I have to stay in a drug trial to get my medication paid for,'' Ashley said. Even though Syprine saved Dawn's life, she's fearful that the drug's cost could make it out of reach for her again. Her solution: Rationing her drugs. Perhaps this will be the year that the Wilson disease drugs Dr. John Walshe discovered and developed more than 50 years ago will be affordable again. But, the human toll and cost to society that the drugs' price spikes caused, remains. ______ 98-year-old drug inventor chastises pharma for ``behaving badly'' I've spent my career reporting medical news. It's an important topic to me because I live with my own health challenge: A rare, genetic condition called Wilson disease that allows copper--an essential dietary mineral--to build up in the liver and brain, leading to copper poisoning that can be fatal. It caused my liver to fail when I was a college student. But I was lucky--I was diagnosed, there was a treatment, and it worked. Before 1955, my disease was fatal. Then, through a series of chance events and serendipities, an English physician, Dr. John Walshe, discovered a drug that turned Wilson disease (WD) into one that could be treated and managed. The drug is known by its generic name, penicillamine, and the brand names, Cuprimine and Depen. While doing research for a book I'm writing on WD, I discovered that Dr. Walshe is still very much alive and well at age 98. So I traveled to Cambridge, England to thank him for saving my life and talk to him about his drug discovery. He invited me to his home, which is a William and Mary style house built in the late 1600s, in the riverside village of Hemingford Grey, near Cambridge. Talking in Dr. Walshe's quintessential English garden, it didn't take him long to attack the pharmaceutical industry that now sells the drug that he discovered and tested. ``The way they're charging for it now is absolutely immoral. There is no other word for it,'' Dr. Walshe told me. ``It is totally immoral. It is business at its worst!'' For more than 20 years I took Cuprimine and never paid more than $60 a month for it. Today, it costs $31,426 a month making it the 13th most expensive prescription drug in 2018. Discovering the first treatment for Wilson disease Listening to the story of Dr. Walshe's drug discovery, it's easy to understand why he's incredulous about its cost. The story began in 1954, when Dr. Walshe traveled to the United States for a Fulbright Fellowship in Boston. ``I was working with Charlie Davidson who was a liver doctor, and we were asked to see a Wilson disease patient who had gone into liver failure,'' said Dr. Walshe. They couldn't do anything to help the patient then, but crossing the ``bridge'' from what was then Boston City Hospital where the patient was being cared for, back to Thorndike Laboratory where he worked, Dr. Walshe had what he calls as inspiration: ``I said to Charlie Davidson, `You know what this chap really needs is penicillamine.' And Charlie Davidson said `What's that?' I told him I discovered this new amino acid that had never been seen in human urine before,'' said Dr. Walshe. Previously, while working in London during the early 1950s, Dr. Walshe had studied laboratory samples from people who were given the antibiotic penicillin. He observed that penicillamine--a derivative of penicillin--binds with copper. It's a process called chelation. His theory was that penicillamine could search out the excess copper in people with Wilson disease, bind with it, and then remove it from the body through urination. Proving his idea To test his theory, Dr. Walshe obtained some penicillamine from a chemist at MIT. Then, he did what would be unheard of today--he tried it on himself first. ``It didn't do me any harm and the next day I was alive and well,'' he said. ``I decided if it was safe for me, it was safe for the patient.'' Dr. Walshe gave penicillamine to the WD patient--who was in liver failure at Boston City Hospital--and as he predicted, it got copper out. When his fellowship in Boston ended, he returned to London with a small supply of penicillamine to continue his experiments there. ``My father was England's leading neurologist at the time, and I asked him to find some Wilson disease patients for me to try it out on,'' said Dr. Walshe. His father came through with a handful of patients, and in 1956 Dr. Walshe reported in the American Journal of Medicine that his drug discovery worked. After that, Dr. Walshe searched for chemical companies willing to make penicillamine so the new treatment could be made available to WD patients as soon as possible. This was years before the start of the current FDA drug approval process that requires costly and extensive testing before a drug can be considered for marketing. Developing an alternative As word spread that there was a treatment for Wilson disease, doctors started prescribing penicillamine for their patients. However, as more patients took it, they found that some developed severe side effects. So, Dr. Walshe looked for a second option. ``We had run into trouble with penicillamine, and I wanted an alternative treatment,'' said Dr. Walshe. By this time he was working at the University of Cambridge, and one morning he ran into a biochemist named Dr. Hal Dixon. Dr. Walshe explained his predicament, and Dr. Dixon pulled a chemical called triethylene tetramine off his laboratory shelf. ``He said it was non-toxic and known to bind with copper,'' said Dr. Walshe. ``He told me to try it, and that's how we got the drug trientine. It was Hal Dixon's idea, and my work proving that it worked and it was safe.'' Walshe made the drug himself For years, Dr. Walshe and his assistant made trientine in their laboratory until they could no longer keep up with demand.Dr. Dixon had explained how to purify the chemical so it would be safe to use in people. So, as he had done with penicillamine, Dr. Walshe searched for a chemical company to make and distribute trientine. In 1985, trientine became the fifth drug approved through the Orphan Drug Act. ``The trouble now is the people who make trientine behave so badly about pricing,'' said Dr. Walshe. ``No doubt about it, they have behaved appallingly badly about pricing.'' Univar Europe charges the UK's National Health Service the equivalent of $96,000 to treat a patient for a year. Because of the high cost, the NHS debated whether or not it could continue paying for the drug in 2019. The North American company Valeant Pharmaceuticals--now Bausch Health--charges even more for its brand-name version, Syprine. Investigating high drug costs In 2016, Senator Susan Collins (R-Maine) launched a bipartisan investigation into the extreme spikes that were being seen in drugs that were off-patent. ``For example, the price of a Valeant drug that is used to treat Wilson disease,'' said Collins, ``increased from $652 per month to more than $21,000 per month. That's more than a 3,000 percent increase in price with no justification.'' ``It's monstrous, it's iniquitous what they're charging for it,'' said Dr. Walshe. For several years he made trientine in his laboratory. ``I sent it out for free on my basic laboratory expense allowance without upsetting it. It was cheap!'' In the United States, Bausch Health now markets Syprine (the brand-name version of trientine) as well as Cuprimine.The company acquired both drugs in 2010 and, soon after, boosted the prices astronomically. Despite extensive adverse publicity, a Congressional hearing, and the addition of generic equivalents the company has yet to lower the drugs' unjustified cost. Walshe never profited from his drug discoveries It's been almost 65 years since Dr. John Walshe had his ``inspiration'' while walking across the bridge at Harvard. I asked him where the idea came from. He simply pointed to the sky and posed the rhetorical question: ``Where do ideas come from?'' Dr. Walshe's discovery of penicillamine and the development of trientine turned Wilson disease from a death sentence into a treatable disease. Today, the challenge for patients is not finding treatment, but being able to pay for it. Dr. Walshe says he never made any money from the two drugs, instead devoting his medical career to helping people with WD. His idea saved my life. Now with the prices being charged for his discoveries, will others be so lucky?