[Senate Hearing 116-39]
[From the U.S. Government Publishing Office]



                                                         S. Hrg. 116-39

                       DRUG PRICING IN AMERICA: 
                   A PRESCRIPTION FOR CHANGE, PART II

=======================================================================

                                HEARING

                               before the

                          COMMITTEE ON FINANCE
                          UNITED STATES SENATE

                     ONE HUNDRED SIXTEENTH CONGRESS

                             FIRST SESSION

                               __________

                           FEBRUARY 26, 2019

                               __________

                                     
             [GRAPHIC(S) NOT AVAILABLE IN TIFF FORMAT]                             


            Printed for the use of the Committee on Finance
            



                                    ________
                       
                       U.S. GOVERNMENT PUBLISHING OFFICE
                
37-143 PDF                       WASHINGTON: 2019


                          
                          
                          
                          COMMITTEE ON FINANCE

                     CHUCK GRASSLEY, Iowa, Chairman

MIKE CRAPO, Idaho                    RON WYDEN, Oregon
PAT ROBERTS, Kansas                  DEBBIE STABENOW, Michigan
MICHAEL B. ENZI, Wyoming             MARIA CANTWELL, Washington
JOHN CORNYN, Texas                   ROBERT MENENDEZ, New Jersey
JOHN THUNE, South Dakota             THOMAS R. CARPER, Delaware
RICHARD BURR, North Carolina         BENJAMIN L. CARDIN, Maryland
JOHNNY ISAKSON, Georgia              SHERROD BROWN, Ohio
ROB PORTMAN, Ohio                    MICHAEL F. BENNET, Colorado
PATRICK J. TOOMEY, Pennsylvania      ROBERT P. CASEY, Jr., Pennsylvania
TIM SCOTT, South Carolina            MARK R. WARNER, Virginia
BILL CASSIDY, Louisiana              SHELDON WHITEHOUSE, Rhode Island
JAMES LANKFORD, Oklahoma             MAGGIE HASSAN, New Hampshire
STEVE DAINES, Montana                CATHERINE CORTEZ MASTO, Nevada
TODD YOUNG, Indiana

             Kolan Davis, Staff Director and Chief Counsel

              Joshua Sheinkman, Democratic Staff Director

                                  (ii)
                                  
                                  
                                  
                                  
                            C O N T E N T S

                              ----------                              

                           OPENING STATEMENTS

                                                                   Page
Grassley, Hon. Chuck, a U.S. Senator from Iowa, chairman, 
  Committee on Finance...........................................     1
Wyden, Hon. Ron, a U.S. Senator from Oregon......................     3

                               WITNESSES

Gonzalez, Richard A., chairman and chief executive officer, 
  AbbVie Inc., North Chicago, IL.................................     6
Soriot, Pascal, chief executive officer, AstraZeneca, Wilmington, 
  DE.............................................................     8
Caforio, Giovanni, M.D., chairman of the board and chief 
  executive officer, Bristol-Myers Squibb Company, New York, NY..     9
Taubert, Jennifer, executive vice president, worldwide chairman, 
  Janssen Pharmaceuticals, Johnson & Johnson, New Brunswick, NJ..    11
Frazier, Kenneth C., chairman and chief executive officer, Merck 
  and Company, Inc., Kenilworth, NJ..............................    12
Bourla, Albert, DVM, Ph.D., chief executive officer, Pfizer, New 
  York, NY.......................................................    14
Brandicourt, Olivier, M.D., chief executive officer, Sanofi, 
  Bridgewater, NJ................................................    15

               ALPHABETICAL LISTING AND APPENDIX MATERIAL

Bourla, Albert, DVM, Ph.D.:
    Testimony....................................................    14
    Prepared statement...........................................    63
    Responses to questions from committee members................    66
Brandicourt, Olivier, M.D.:
    Testimony....................................................    15
    Prepared statement...........................................   134
    Responses to questions from committee members................   144
Caforio, Giovanni, M.D.:
    Testimony....................................................     9
    Prepared statement...........................................   474
    Responses to questions from committee members................   475
Frazier, Kenneth C.:
    Testimony....................................................    12
    Prepared statement...........................................   495
    Responses to questions from committee members................   497
Gonzalez, Richard A.:
    Testimony....................................................     6
    Prepared statement...........................................   527
    Responses to questions from committee members................   528
Grassley, Hon. Chuck:
    Opening statement............................................     1
    Prepared statement...........................................   704
Soriot, Pascal:
    Testimony....................................................     8
    Prepared statement...........................................   705
    Responses to questions from committee members................   713
Taubert, Jennifer:
    Testimony....................................................    11
    Prepared statement...........................................   839
    Responses to questions from committee members................   845
Thune, Hon. John:
    Submission, 340B Health...................................... 1,053
Wyden, Hon. Ron:
    Opening statement............................................     3
    Prepared statement........................................... 1,054

                             Communications

AARP............................................................. 1,057
American Society of Health-System Pharmacists.................... 1,058
Coalition for Affordable Prescription Drugs...................... 1,062
George, Linda.................................................... 1,064
Huszagh, Robin K................................................. 1,065
Interfaith Center on Corporate Responsibility.................... 1,066
National Association of Free and Charitable Clinics.............. 1,070
National Business Group on Health................................ 1,072
National Coordinating Committee for Multiemployer Plans.......... 1,076
Oxfam America.................................................... 1,078
Patients for Affordable Drugs Now................................ 1,080
Pharmaceutical Care Management Association....................... 1,084
Raffle, Debra L.................................................. 1,089
Ricci, Laura T................................................... 1,091
Rowland, Rhonda.................................................. 1,099




 
                        DRUG PRICING IN AMERICA:
                   A PRESCRIPTION FOR CHANGE, PART II

                              ----------                              


                       TUESDAY, FEBRUARY 26, 2019

                                       U.S. Senate,
                                      Committee on Finance,
                                                    Washington, DC.
    The hearing was convened, pursuant to notice, at 10:15 
a.m., in room SD-215, Dirksen Senate Office Building, Hon. 
Chuck Grassley (chairman of the committee) presiding.
    Present: Senators Roberts, Enzi, Cornyn, Thune, Isakson, 
Portman, Toomey, Scott, Cassidy, Lankford, Daines, Young, 
Wyden, Stabenow, Cantwell, Menendez, Carper, Cardin, Brown, 
Bennet, Casey, Whitehouse, Hassan, and Cortez Masto.
    Also present: Republican staff: Chris Allen, Senior Advisor 
for Benefits and Exempt Organizations; Brett Baker, Health 
Policy Advisor; Stuart Portman, Health Care Policy Advisor; 
Karen Summar, Chief Health Policy Advisor; and Jeff Wrase, 
Deputy Chief of Staff and Chief Economist. Democratic staff: 
Michael Evans, General Counsel; Peter Gartrell, Investigator; 
Matt Kazan, Senior Health Policy Advisor; Kristen Lunde, 
Winston Fellow; and Joshua Sheinkman, Staff Director.

 OPENING STATEMENT OF HON. CHUCK GRASSLEY, A U.S. SENATOR FROM 
              IOWA, CHAIRMAN, COMMITTEE ON FINANCE

    The Chairman. I want to welcome and to thank our witnesses 
for being here. We know that you put a lot of hard work into 
it, and staffs and the Senators have done the same thing.
    The information that these witnesses will share will help 
inform the committee as it addresses the issues of high 
prescription drug prices. America has a problem with the high 
cost of prescription medicines.
    Whether it is about EpiPen, insulin, or other 
prescriptions, in the thousands of letters that I have 
received, Iowans have made clear that high drug prices are 
hurting. I have heard from people about skipping doses of their 
prescription drugs to make them last until the next paycheck.
    Of course, I am not a doctor, but rationing one medicine 
does not sound like the safe prescription for health and 
wellness that Americans want. Others have told me about leaving 
their prescription on the pharmacy counter because it costs too 
much.
    There is no question that researchers and doctors have 
developed treatments and cures for diseases where there were 
once no such cures or treatments. And such innovations take 
time and money. I think all of us at this table--and most 
people who are not at this table--if they study at all the 
pharmaceutical industry and the FDA process, they know it takes 
time and money. But we are all trying to understand the sticker 
shock that many drugs generate, especially when some of these 
drugs have been around for a long, long time.
    There is a balance then between incentivizing innovation 
and keeping prices affordable for consumers and taxpayers. And 
the taxpayers are involved, because the Federal Government is a 
great purchaser of drugs through a lot of health programs.
    Like all systems, things can get out of balance. The good 
news is that we are here to discuss solutions. And we thank all 
of you for cooperating with us in that effort today.
    In fact, we are here today thanks to a system of checks and 
balances that is within our Constitution. Congress has a 
constitutional responsibility to be a meaningful check on the 
spending of taxpayers' money. That responsibility includes not 
just holding hearings, but also holding the private sector and 
the government accountable through oversight, just like a 
doctor. That doctor has to properly diagnose a disease before 
it can be treated. Congress needs to understand what is going 
on in the drug pricing supply chain in order to respond in a 
measured and effective way.
    As part of that fact-finding, as of the last Friday Ranking 
Member Wyden and I launched an inquiry into the high cost of 
insulin. This hearing is not about scapegoating any one group 
regarding high drug costs. That is why we are holding a series 
of bipartisan hearings on this issue.
    Without a doubt, drug pricing is a complex issue. But I 
think we should also be asking whether or not it is too complex 
or whether it should be so complex. We cannot allow anyone to 
hide behind the current complexities to shield the true cost of 
drugs. And we should not turn a blind eye to industry practices 
that thwart laws and regulations designed to promote 
competition and generic drug entries into the marketplace.
    Health and Human Services Secretary Alex Azar, FDA 
Commissioner Scott Gottlieb, and the Federal Trade Commission 
have identified a number of tactics that undermine competition, 
like withholding samples, pay-for-delay, product hopping, and 
rebate bundling. And that just names a few. While these 
agencies are taking enforcement action or looking at regulatory 
changes, we here in Congress are exploring legislative options 
to deter companies from engaging in these practices that keep 
drug prices high for patients.
    Today we expect open, honest answers from the 
pharmaceutical industry to figure out how we got where we are 
today and to see what ideas they have to make things better.
    One of the first things that we need to talk about is 
pretty simple: list price. Now you folks are probably going to 
tell us it is not that simple. Secretary Azar has said that 
pharmaceutical companies believe that the list price is 
meaningless. In fact, some of your testimony today will echo 
that.
    However, for a patient taking a drug that has no 
competition, the list price then becomes very meaningful. For 
seniors on Part D or paying coinsurance as a percentage of list 
price, then for that person, list price is very meaningful. For 
people who have high-
deductible plans and pay thousands of dollars towards the list 
price, then for those people, the list price is very 
meaningful.
    For pharmacy benefit managers, providing drugs with a high 
list price can be more attractive than providing a less 
expensive drug. Therefore, for the taxpayers then, the list 
price becomes very meaningful.
    We have all seen the finger-pointing. Every link in the 
supply chain has gotten skilled at that finger-pointing. But 
like most Americans, I at least--I think like most members of 
Congress--am sick and tired of the blame game.
    It is time then for solutions. One way or another, we are 
going to get some clarity. The American people deserve straight 
answers and real solutions.
    On that note, I want to remind each of our witnesses that 
it is a crime under title 18, section 101 to provide false 
testimony to Congress. I thank you all for coming.
    [The prepared statement of Chairman Grassley appears in the 
appendix.]
    The Chairman. Senator Wyden?

             OPENING STATEMENT OF HON. RON WYDEN, 
                   A U.S. SENATOR FROM OREGON

    Senator Wyden. Thank you very much, Mr. Chairman.
    And I just want to note, at the outset, our focus on 
bipartisanship. We began that with our effort to go after price 
gouging with hepatitis C. Recently we have gone after 
manufacturers ripping off Medicaid. You noted our investigation 
to look at insulin prices that just soar and soar and soar some 
more. So I just very much appreciate the fact that we are 
tackling this in a bipartisan way.
    Colleagues, prescription drugs did not become outrageously 
expensive by accident. It is not the result of a system too 
complicated for Americans to understand. Drug prices are 
astronomically high because that is where pharmaceutical 
companies and their investors want them. The brakes have come 
off pharmaceutical pricing, and American families are hurtling 
along in the passenger seat terrified about what comes next.
    Today the committee is going to hear about uplifting 
stories and miracle cures. Yet it is morally repugnant when 
patients cannot afford those miracles. It is morally repugnant 
when ailing patients are forced to choose between filling the 
next prescription or putting food on the table because they 
cannot afford both. It is morally repugnant when patients are 
forced to skip doses.
    Pharma executives, all of you who are here today, are here 
because the way you have been doing business is unacceptable. 
Ten companies accounted for half of all the profits in the 
health-care sector last year. Nine of them were drug 
manufacturers. All but one of today's witnesses represent 
companies on this list.
    Drugmakers behave as if the patients and the taxpayers are 
unlocked ATMs full of cash to be extracted, and their 
shareholders are the customers whom they value above anybody 
else. So I am going to go through a short list of examples 
starting with AbbVie, which manufactures the top-selling 
prescription drug in America, the arthritis medication Humira.
    Over 6 years, the company doubled the price of a 12-month 
supply from $19,000 to $38,000. Can the patients opt for a less 
expensive alternative? They cannot, because AbbVie protects the 
exclusivity of Humira like Gollum with his ring--thick cobwebs 
of patents and legal tricks and shadowy deals with other 
drugmakers. All of them are in place to keep the cash flowing.
    Now I also want to address some very troubling information 
we just got from AbbVie's proxy statement. It is a document 
every publicly traded company has to file with the SEC. Page 37 
shows that in 2017, a portion of CEO Richard Gonzalez's multi-
million-dollar bonus was directly tied to sales of Humira. It 
appears the same incentive was in place in 2015 and 2016. In 
fact, the committee's review shows that all of AbbVie's top 
executives have the same arrangement.
    Mr. Gonzalez is welcome to respond, but the implication 
ought to be clear. From top down, AbbVie's leadership had 
reason to keep pushing prices and sales up.
    Now Pfizer, that company gets first prize for the emptiest 
pricing gesture in 2018. After stern Trump tweets, Pfizer said 
it would temporarily freeze the prices. But once the President 
got his flashy headlines, his gaze went elsewhere. Pfizer's 
former CEO told investors it was back to normal, another round 
of price hikes in 2019, including the pain medication Lyrica. 
Lyrica has increased 163 percent in price since 2012. Just one 
drug allowed Pfizer to pull in $4.5 billion in 2017.
    Merck gets second prize for emptiest pricing gesture of 
2018. They made sweet-sounding promises after coming under 
criticism, but they cut prices for drugs that essentially 
produce no revenue for the company. Left untouched were the 
cash cows Keytruda and Januvia, which account for more than a 
quarter of the company's revenue. It is like promising car 
shoppers a great deal, except the only discounted model on the 
lot is an Edsel.
    Sanofi--this is a company wringing more and more cash out 
of people with an incurable disease. In 2010, a vial of this 
insulin cost less than $100. In 2018, it cost nearly $300. The 
company raised prices again in 2019. Considering the landmark 
breakthrough on insulin came early in the roaring 20s, nothing 
could justify this sudden price hike a century later. Diabetics 
who cannot afford the cost now self-ration and endanger their 
lives. But you know what? Investors are happy.
    AstraZeneca--a lesson in saying the quiet part out loud. In 
an interview earlier, the CEO complained that his $12-million 
salary made him the lowest-paid CEO in the whole industry, and 
he said it was annoying to some extent. His company, meanwhile, 
continues to raise the price of Symbicort, its $3-billion 
asthma drug. For some asthmatics, being able to breathe costs 
hundreds of dollars a month.
    And Johnson & Johnson gets the record today for flip-
flopping. This January 7th at the JP Morgan Health Conference, 
the CEO said the pharmaceutical industry needs self-policing on 
prices. That sounded good, but 3 days later the company hiked 
the prices of hundreds of its drugs, including drugs that 
account for billions in Medicare spending.
    And finally, there is Bristol-Myers Squibb. In 2017, the 
company spent roughly $11 billion on dividends, stock buybacks, 
marketing, sales, and administrative costs that roughly triple 
the amount spent on R&D.
    Now I am going to close by saying that I want us to compare 
these concrete examples of two-faced scheming and profiteering 
with the central arguments that we are going to get this 
morning. The central argument from pharma is basically, the 
fault is always somebody else's. The health plans are at fault, 
the pharmaceutical benefit managers are at fault, regulators 
are at fault. What we know for certain is the history that 
pharma CEOs always say somebody else is at fault.
    We are also going to hear that the list price does not 
matter, that the true costs are just so complicated. But 
companies do not set and raise list prices for fun. Those 
prices are directly tied to the amount patients pay out-of-
pocket at pharmacy windows from sea to shining sea. They are 
directly tied to what taxpayers spend on health-care programs.
    Then drugmakers point the finger at middlemen, the pharmacy 
benefit managers. I have said for years these pharmacy managers 
are wasteful and secretive, and take their cut without proving 
their worth to anybody. They are going to have their day before 
the committee too. But those pharmacy managers do not set list 
prices. The manufacturers do.
    And by the way, the manufacturers do not offer rebates for 
nearly 40 percent of Part D brand-name drugs. Those prices are 
going up. That is on the drug companies, not on the pharmacy 
managers.
    We are also going to hear that any changes in business as 
usual hurt research and development. A quick look at company 
finances shows that that is a fable. Revenue generated from 
American patients alone dwarfs what they spend on R&D 
worldwide.
    Drugmakers spend as much, if not more, on those 
exhilarating TV ads and office-to-office salesmen as they spend 
on research and development. And if lower prices would diminish 
R&D, why don't costly dividends? Why don't stock buybacks? Is 
the stock price more important than inventing that next miracle 
cure? Even if you buy the specious argument that a drug's list 
price at launch is driven by research costs, what could justify 
arbitrary price increases year after year, long after the 
research and development spending is done?
    Finally, we are going to hear about how patients can get 
coupons. But if this was so generous, why can't drug companies 
just lower prices across the board? I believe it is just more 
slick branding, branding that allows companies to keep the 
status quo cash cow rolling along.
    I will close with this. I was there when seven big tobacco 
CEOs testified in a committee room just like this one. They 
lied that day. This committee, the chairman and I, expect 
better than that this morning.
    Your profits are outsized compared to others in the 
industry. You get a massive portion of your revenue from 
American taxpayers, and you bear none of the consequences of 
these skyrocketing prices. It is long past time to drop the 
excuses and take concrete action to make medicine in America 
more affordable.
    Thank you, Mr. Chairman.
    [The prepared statement of Senator Wyden appears in the 
appendix.]
    The Chairman. Now I will introduce our seven witnesses, but 
once again, thank you for participating in this very important 
hearing on a very important topic. We are grateful for your 
participation and cooperation with our committee.
    The first witness is Richard Gonzalez, chairman and chief 
executive officer of AbbVie, Incorporated. Then we will hear 
from Pascal Soriot, DVM, executive director and chief executive 
officer of AstraZeneca. Then we will hear from Giovanni 
Caforio, M.D., chairman of the board and chief executive 
officer, Bristol-Myers Squibb; then Jennifer Taubert, executive 
vice president and worldwide chairman of pharmaceuticals for 
Johnson & Johnson; Kenneth C. Frazier, chairman and chief 
executive officer of Merck and Company; Albert Bourla, DVM, 
Ph.D., chief executive officer of Pfizer; and Dr. Olivier 
Brandicourt, M.D., chief executive officer of Sanofi.
    We welcome all of you, and we will start in that direction. 
And you have been given 5 minutes. I do not gavel you down at 
the end of 5 minutes, but I wish when the red light would come 
on, you would start to summarize, if you have not finished.
    So we will start with Mr. Gonzalez.

STATEMENT OF RICHARD A. GONZALEZ, CHAIRMAN AND CHIEF EXECUTIVE 
            OFFICER, ABBVIE INC., NORTH CHICAGO, IL

    Mr. Gonzalez. Thank you, Chairman Grassley, Ranking Member 
Wyden, and members of the committee.
    I am Richard Gonzalez, and I am the chief executive officer 
of AbbVie, a company dedicated to developing new innovative 
medicines for some of health care's most challenging diseases, 
such as cancer, Alzheimer's, viral infections, and autoimmune 
diseases.
    Since our inception in 2013, AbbVie has invested 
approximately $50 billion in pursuit of that goal. However, 
because we were tackling some of medicine's most challenging 
problems, solutions do not come easily, nor without significant 
risks.
    Where we have succeeded, we have been able to provide cures 
for fatal diseases like hepatitis C and significantly alter the 
disease progression for certain cancers, lessening the burden 
of illness on patients and on the health-care system. This is 
what the 30,000 employees of AbbVie are dedicated to doing.
    We agree that access to life-saving medicines is a critical 
issue, and we look forward to sharing our perspectives with 
you. There is no one solution to this complex issue, but AbbVie 
is committed to working with the committee and others on how we 
can better partner in your efforts to address pharmaceutical 
pricing and access. AbbVie and the rest of our industry must 
play a role in solving these issues and be prepared to work 
together with the insurance industry, the administration, and 
you to find a better path for American patients.
    My remarks today will focus on one aspect of this inquiry, 
the Medicare Part D benefit design, which, even after 
pharmaceutical list prices are lowered, still contributes to 
making innovative therapies cost-prohibitive for many Medicare 
patients.
    In general, the Medicare Part D program has worked well. 
Its market-based structure and utilization of formularies 
encourages competitive price discounts that have yielded 
significant savings to the government since the Part D benefit 
went into place back in 2006. However, despite these cost 
savings, Part D patient out-of-pocket costs have significantly 
increased. Some would blame that solely on high drug prices, 
and we agree that price should be part of the discussion. But 
it is also important to acknowledge that science has enabled us 
to advance the standard of care far beyond what was possible 
when the Part D benefit was originally designed.
    Many of today's specialty medicines offer significant 
advancements in treating or curing serious chronic or life-
threatening conditions and save significant amounts of money 
for the health-care system by decreasing overall health-care 
costs. Yet these therapies are also costly.
    Due to the structure of the Part D benefit design, patients 
are charged out-of-pocket costs on a medicine's list price, 
which does not reflect the market-based rebates or discounts 
that Medicare receives. We are encouraged by the proposed rule 
that would reflect manufacturer's discounts in patient's Part D 
out-of-pocket payments. This is an important step in the right 
direction, but we believe more must still be done to help Part 
D patients.
    Let me give you a recent real-world example that 
demonstrates the challenge with the current Part D benefit 
design, and why the focus solely on list price does not fully 
address the access challenges. An uninsured hepatitis C 
infection leads to downstream medical costs for surgery, 
chemotherapy, and radiation for patients who progress to 
needing a liver transplant or having liver cancer. Today we can 
cure hepatitis C with drugs. This cure is highly cost-effective 
for the overall health-care system.
    In 2017, AbbVie launched Mavyret, a highly effective cure 
for HCV. At the time, the list prices for the competitive 
alternatives were as high as $94,500 for the most commonly 
prescribed treatment duration. We launched Mavyret at a list 
price that was 72 percent lower. But even though we cut the 
list price of an HCV cure--for most patients by 72 percent--
Medicare Part D patients' out-of-pocket obligations are still 
too high for many patients to access this medicine.
    We believe it is important that discussions about access 
and affordability include a focus on how to alleviate Medicare 
Part D out-of-pocket burdens above and beyond just lowering 
list price. We are prepared to step up and discuss how 
companies like ours can shoulder more of the burden of the 
patient out-of-pocket expense as we do in other areas.
    We believe AbbVie, the rest of the pharmaceutical industry, 
and the insurance providers should come together with the 
administration and you to work towards solutions that make 
life-changing medicines more affordable to Part D patients. I 
can assure you AbbVie is committed to doing its part, and we 
look forward to working with you.
    Thank you.
    [The prepared statement of Mr. Gonzalez appears in the 
appendix.]
    The Chairman. Mr. Soriot?

     STATEMENT OF PASCAL SORIOT, CHIEF EXECUTIVE OFFICER, 
                  ASTRAZENECA, WILMINGTON, DE

    Mr. Soriot. Chairman Grassley, Ranking Member Wyden, and 
members of the committee, good morning. I appreciate the 
invitation to address concerns regarding the pricing of 
medicines in the United States.
    My name is Pascal Soriot, and I am the CEO of AstraZeneca. 
Our company is dedicated to science and innovation. And in 
2018, we invested nearly $6 billion in research and 
development, 28 percent of our product sales, which is well 
above the industry average.
    In the past 2 years, our commitment to R&D has resulted in 
18 significant FDA approvals and 5 breakthrough designations. 
However, I know that these statistics are meaningless unless 
patients can actually afford our medicines and those medicines 
reduce overall health-care costs.
    I am here to discuss how we can work with other 
stakeholders to take specific actions that address pricing 
concerns. My first proposal is that we move away from the 
current rebate system while continuing to work with payers and 
PBMs to ensure robust negotiations.
    The current system is built on high list prices coupled 
with rebates. This is not sustainable, and all of us have a 
role to play. For example, the estimates for 2018 show that 
across our medicines, our average rebate is nearly 50 percent 
of our gross revenues in the U.S. Despite this, in recent years 
in our primary care portfolio, we have seen flat to declining 
net effective prices for most of our medicines. As a company 
dependent upon government action for eliminating rebates in 
commercial and in Part D, we are prepared to reduce our list 
prices by an equivalent amount of rebates, less the appropriate 
market-based fees, to those in the supply chain. This will 
actually reduce overall costs not only for patients, but also 
for the government.
    My second proposal is that if a change of the current 
system is not possible, a portion of discounts and rebates 
could be used to create out-of-pocket caps for Medicare 
patients. This approach is used successfully in some other 
countries. Actually, it gives patients greater certainty in 
their out-of-pocket cost.
    Third, I believe that value-based agreements have the 
potential to transform how medicines are priced and reimbursed 
in the U.S. In our own value-based agreements, the price of a 
medicine is directly linked to the value it provides to 
patients, to payers, and to the health-care system.
    For example, last month we announced an agreement for 
University of Pittsburgh Medical Center Medicare patients who 
are prescribed Brilinta. This innovative contract directly 
reduces the cost for patients, and it ties price to clinical 
value, basing our payments on patient outcome. These types of 
agreements can be especially effective for medicines where 
there is limited competition. As an example, for one of our 
oral oncology medicines we agreed to reimburse a large payer 
for discontinued use because patients did not respond to 
treatment. And we have reimbursed the payer under those 
agreements 20 percent of the time.
    To that end, I appreciate the support of Senator Warner and 
Senator Cassidy for value-based agreements, as demonstrated by 
their request for input on the Patient Affordability, Value, 
and Efficiency, the PAVE Act.
    My fourth proposal is that we must encourage biosimilars 
and eliminate policy and commercial barriers to their greater 
use. Biologics are actually making very important contributions 
to medicine, and I believe a vigorous biosimilar market would 
reduce costs like generics do for small molecules. In fact, 
biosimilars have gained up to 85 percent market share in the 5 
largest countries in Europe, and the average biosimilar 
discount is between 40 and 80 percent.
    In closing, I would like to emphasize my strong commitment 
to addressing the concerns raised by the committee. I believe 
that we can work together to find solutions that continue to 
allow manufacturers to innovate, while creating a more 
efficient and more affordable system.
    There are no easy answers, it is very clear, but we want to 
be a constructive partner. Thank you, and I look forward to the 
discussion.
    [The prepared statement of Mr. Soriot appears in the 
appendix.]
    The Chairman. Dr. Caforio?

STATEMENT OF GIOVANNI CAFORIO, M.D., CHAIRMAN OF THE BOARD AND 
  CHIEF EXECUTIVE OFFICER, BRISTOL-MEYERS SQUIBB COMPANY, NEW 
                            YORK, NY

    Dr. Caforio. Chairman Grassley, Ranking Member Wyden, and 
members of the committee, good morning, and thank you for the 
opportunity to be here today on behalf of the 24,000 employees 
of Bristol-Myers Squibb. I look forward to working together to 
align incentives to ensure all Americans have access to the 
medicines they need.
    I am a physician. I joined the pharmaceutical industry 30 
years ago because of the impact companies like ours have on 
patients.
    We should all be proud that American companies lead our 
industry. Our researchers have contributed to the development 
of medicines that have reduced mortality from cardiovascular 
disease, helped transform HIV/AIDS into a chronic disease, and 
are now making significant progress with the treatment of 
cancer.
    Just 10 years ago, the idea of harnessing the immune system 
to treat cancer was viewed with great skepticism. But our 
researchers saw the promise of that approach and ignited an era 
of scientific innovation that has changed survival expectations 
in multiple tumors. Prior to the availability of immuno-
oncology treatments, only 25 percent of patients diagnosed with 
metastatic melanoma were alive after 1 year. Today, thanks to 
immuno-oncology therapies, that number has increased to 74 
percent.
    The potential of this approach has also been seen in lung 
cancer, kidney cancer, and many other difficult-to-treat 
tumors. These patients now have a chance for quality and long-
term survival.
    But not all patients respond to current immunotherapies. 
And so we must do more. We recently opened a new facility 
dedicated to investigating what we call immuno-oncology 
resistance. And we continuously seek external innovation to 
augment our pipeline. In fact, in this context, we recently 
announced our plans to acquire Celgene. Our goal is to bring 
together the drive and dedication of two science-driven 
companies to do even more for patients.
    As a physician, I do recognize that medicines are only 
helpful if patients and health-care systems can afford them. We 
share the committee's concern with escalating health-care costs 
and believe that our responsibility extends to ensuring that 
patients have access to and can afford our medicines. For this 
reason, the average net pricing across our U.S. portfolio of 
medicines increased by 5 percent or less year-over-year for the 
last 5 years. Importantly, it did not increase at all in 2018. 
And we expect that it will not increase in 2019.
    Despite this fact, we do recognize that patients' out-of-
pocket costs continue to increase. We believe it is possible to 
work together to realign incentives to ensure patients can 
afford medicines without stifling scientific innovation. So 
what are the solutions? We are supportive of the proposed rule 
aimed at reforming the rebate system with a focus on what is 
best for patients.
    We need to ensure more generics are available whenever 
permissible under our system. We support value-based purchasing 
arrangements that tie payments to value. These models can 
reduce costs, improve access and patient adherence, and 
contribute to better outcomes.
    We applaud efforts by Health and Human Services and this 
committee in all of these areas. We do believe the U.S. should 
not adopt policies that stifle innovation in other countries. 
Outside of the U.S., reimbursement of new medicines often takes 
more than 2 years. For example, nearly 4 years ago our Opdivo 
and Yervoy regimen was first approved to treat metastatic 
melanoma in the U.S. Today, 6 of the 16 countries included in 
the international price index proposal still do not provide 
reimbursement for this combination, which is the standard of 
care for the treatment of this cancer. This is why we do not 
support the proposed international price index model for 
Medicare Part B drugs.
    I would like to leave you with a few thoughts. First, we 
recognize the need for change. We are witnessing a historic era 
in biomedical innovation. American research-based companies are 
leading the way to help patients whose diseases cannot be 
adequately treated with today's medicines. But we must ensure 
that patients have affordable access to new innovations. And we 
should work on policies that support and reward access and 
these investments. I look forward to working together to 
implement real change that broadens access to innovative 
medicines for patients.
    In closing, on behalf of my colleagues at Bristol-Myers 
Squibb and the patients we serve, my sincere thanks for your 
time and attention today.
    The Chairman. Thank you very much.
    [The prepared statement of Dr. Caforio appears in the 
appendix.]
    The Chairman. Now, Ms. Taubert?

   STATEMENT OF JENNIFER TAUBERT, EXECUTIVE VICE PRESIDENT, 
WORLDWIDE CHAIRMAN, JANSSEN PHARMACEUTICALS, JOHNSON & JOHNSON, 
                       NEW BRUNSWICK, NJ

    Ms. Taubert. Chairman Grassley, Ranking Member Wyden, 
members of the committee, thank you for the opportunity to be 
here today. I am Jennifer Taubert, and I lead the Janssen 
Pharmaceutical Companies of Johnson & Johnson. We focus on 
discovering and developing transformational medicines for some 
of the world's most challenging diseases, including multiple 
myeloma, prostate cancer, HIV, schizophrenia, and Crohn's 
disease, among others.
    Like many of you, I know what it is like when a loved one 
faces serious illness. My own mother died of lung cancer while 
in her 40s, and at that time there was very little that could 
be done for her. I have committed my career to bringing 
families hope: hope for years of life, for the chance to be 
there for a daughter's wedding or for a grandson's birth.
    Janssen invested $8.4 billion in research and development 
last year in the search for medical breakthroughs, making us 
one of the world's top R&D investors in any industry. In fact, 
our investment in R&D last year was 86 percent more than we 
spent on sales and marketing. And this substantial investment 
is changing lives. It has helped turn HIV from a death sentence 
to a manageable disease. Our targeted cancer medicines have 
helped patients with some of the most deadly cancers live 
longer, in some cases for many years.
    Medicines not only help patients and families. They also 
help lower overall health-care costs by keeping people well, 
preventing the need for expensive procedures and 
hospitalizations. But medicines cannot make a difference if the 
patients who need them cannot afford them. We understand the 
concerns about the cost of health care.
    Our approach recognizes our responsibility to patients 
today and patients tomorrow. Patients today need access to our 
medicines. Patients tomorrow count on us to deliver cures and 
treatments for the most challenging diseases. When we price our 
medicines, we balance the value to patients, the importance of 
affordable access, and the importance of developing future 
breakthroughs. The list price is a starting point that is 
reduced by required discounts to government programs and 
rebates to payers so they will grant patients access to our 
medicines.
    Last year our discounts and rebates amounted to $21 billion 
and our net price decreased 6.8 percent. Unfortunately, while 
our overall price decreased for the past 2 years, patients have 
seen their out-of-pocket costs go up. One reason is increased 
enrollment in health plans that require patients to pay more 
for their prescriptions. As one recent analysis shows, patients 
are required to pay 13 percent of overall pharmaceutical costs, 
versus only 3 percent of hospital costs, even though medicine 
can help keep patients out of the hospital.
    Above all, we need an American solution to this American 
challenge. We must ensure that today's medicines are 
affordable, while at the same time preserving the innovation 
that has delivered so much and promises even more. We must 
maintain the hallmarks that make American health care 
remarkable: access to innovative therapies, personal choice, 
and doctors and patients making decisions based on what is 
right for each individual.
    At Janssen, we are committed to being a part of the 
solution. We believe open dialogue is essential. That is why in 
2016, we began issuing the Janssen Transparency Report, sharing 
information about how we invest our resources, price our 
medicines, and help people access them. And we recently 
announced our plan to include list price and potential patient 
out-of-pocket costs in our direct-to-consumer TV advertising. 
In the same spirit of open dialogue, we have consistently 
brought forward ideas and perspectives to both Congress and the 
administration to fix what is not working while preserving what 
is.
    We have included more details in our submitted testimony, 
but I want to touch on a few points today. First, while 
Medicare Part D is working for many seniors and has been 
effective in containing costs, we believe an out-of-pocket cap 
is a needed protection.
    Second, in Medicare Part B, we have proposed options that 
would allow Medicare to continue to achieve negotiated savings 
through market competition while reducing costs.
    And third, we support rebate reforms that ensure patients 
benefit from the negotiated rebates and discounts--$150 billion 
in total in 2017 alone--and as a result, have patients see 
lower out-of-pocket costs at the pharmacy.
    We are on the verge of extraordinary progress that could 
change our lives and the lives of our children and 
grandchildren. At Janssen, we are committed to bringing that 
promise to life.
    Thank you very much.
    The Chairman. Thank you.
    [The prepared statement of Ms. Taubert appears in the 
appendix.]
    The Chairman. Mr. Frazier?

 STATEMENT OF KENNETH C. FRAZIER, CHAIRMAN AND CHIEF EXECUTIVE 
        OFFICER, MERCK AND COMPANY, INC., KENILWORTH, NJ

    Mr. Frazier. Mr. Chairman, Ranking Member Wyden, and 
members of the committee, thank you for the opportunity to 
appear here today.
    Merck's mission is to save and improve lives around the 
world by bringing forward breakthrough medicines and vaccines. 
Research is at the core of Merck. Last year we invested $10 
billion in R&D, 23 percent of product sales. And we have 
invested nearly $70 billion over the past decade.
    Over the last 5 years, we have also made capital 
investments of over $5 billion in the United States, and we 
plan to invest more than $9 billion more over the next few 
years to increase manufacturing capacity and to open two new 
research centers in the United States.
    We go where the science leads us, which means we do not 
focus only on diseases in wealthier countries. For example, we 
are proud to have deployed 70,000 doses of our experimental 
Ebola vaccine in the Congo, working in partnership with the 
United States government. The goal is to save lives even where 
no viable commercial opportunity exists. We do all this to 
serve patients.
    We fully understand that U.S. patients are having a harder 
and harder time affording the medicines they need. While 
medicine costs are growing at the slowest rate in years, our 
patients are too often being asked to pay more out of pocket. I 
am here to suggest some ways that together we can address this 
problem. First, we want to be clear that our industry has a 
duty to be responsible in our pricing practices and to 
contribute to solutions that address patient affordability.
    Merck has a history of responsible pricing. We publish 
information about our prices, and the rebates and discounts we 
provide to payers. Last year we pledged that we will not 
increase our average net prices across our portfolio by more 
than the rate of inflation annually
    Second, we must ensure that patients get the benefit of 
these large rebates and discounts. The incentives in the 
current system are badly misaligned with the growing gap 
between list and net prices, creating incentives to favor 
products with higher list prices. This misalignment hurts 
patients because their cost sharing is often based on the list 
price of a drug. We urge you to support action to ensure that 
patients benefit from these discounts.
    Third, we can significantly reduce drug spending for 
patients in the health-care system by ensuring that we have a 
viable biosimilars market in the United States. We urge 
Congress to encourage and support greater biosimilar 
utilization.
    Fourth, we believe that prices can better align with a 
drug's value, when manufacturers and payers are able to 
negotiate innovative contracts that base payment on a drug's 
benefit. We need to move to this type of system, but there 
remain major regulatory and operational obstacles to such 
value-based arrangements, which we urge Congress to address. We 
agree that manufacturers should be rewarded based on the value 
that our therapies deliver.
    Fifth, we support efforts to encourage generic competition. 
A version of Chairman Grassley's CREATES Act and similar 
policies could make needed reforms to encourage generic 
competition and ensure there is no inappropriate gaming of the 
system. We also support eliminating coupons in cases where 
brand name generic competition exists.
    Finally, we would like to work with the committee to find 
ways to end price gouging by some who excessively increase off-
patent drug prices where there is no competition. These high 
prices hurt patients, and they do not create incentives for 
research. These changes could bring real relief to today's 
patients while preserving the incentives to invest in 
tomorrow's breakthroughs. Decades of research investment are 
now yielding life-changing discoveries. If we damage the 
biomedical ecosystem that thrives on these investments, we will 
surely limit what can be achieved for patients and society.
    The single most important thing we do at Merck is to 
persist in making large and risky investments in R&D that allow 
our thousands of researchers to sit at their lab benches to try 
to create something transformative despite the overwhelming 
odds that their efforts will not succeed, since more than 9 out 
of 10 compounds fail.
    I would like to end on a brief personal note. My mother 
died when I was a child, and my siblings and I were raised by 
my father. He was a giant in my life, and I was devastated when 
Alzheimer's took him away from us.
    Last year, after spending many years and over $1 billion, 
Merck had to end development of a promising Alzheimer's therapy 
because it did not work. Yet we continue on, seeking better 
approaches, and I truly believe that Merck or one of the other 
companies at this table will find a medicine that will avoid 
the pain of seeing a loved one taken away from them in this 
way.
    This vital work depends on having a U.S. market that is 
free, competitive, and predictable. We must work together to 
solve the affordability challenges of today's patients without 
jeopardizing the hopes of those waiting for tomorrow's cures. 
The changes I have discussed today have the potential to vastly 
improve the market while lessening the financial hardships many 
people face.
    I am here to pledge Merck's cooperation with you in 
creating such changes. Thank you very much.
    The Chairman. Thank you, Mr. Frazier.
    [The prepared statement of Mr. Frazier appears in the 
appendix.]
    The Chairman. Now, Dr. Bourla?

            STATEMENT OF ALBERT BOURLA, DVM, Ph.D., 
         CHIEF EXECUTIVE OFFICER, PFIZER, NEW YORK, NY

    Dr. Bourla. Good morning. Chairman Grassley, Ranking Member 
Wyden, and members of the committee, thank you for the 
invitation. My name is Albert Bourla. I have been with Pfizer 
26 years and just last month became its chief executive 
officer.
    I have to say that today I am particularly humbled to take 
part in such an important policy discussion within the United 
States Senate. When I immigrated into the United States 18 
years ago, I could never have imagined such an honor.
    In that frightening moment when you hear that you or a 
loved one has been diagnosed with a serious disease, one 
question comes to mind: is there a treatment available? The 
answer to this question will change your life. Happily the 
answer, increasingly, is ``yes.''
    New breakthroughs are coming quickly to treat many 
difficult and devastating diseases. But these breakthroughs 
will not do anyone any good if patients cannot afford them. And 
unfortunately, the horribly misaligned incentives within our 
health-care system often make medicines unaffordable for 
American patients. We need to fix this. Today, we would like to 
propose four ideas to drive meaningful savings for patients.
    The first idea is passing all rebates to patients. Pfizer 
supports a system in which transparent up-front discounts 
directly benefit patients, rather than the system where rebates 
are swallowed up by the supply chain. In the current system, 
for example, none of the approximately $12 billion that Pfizer 
paid in rebates, in 2018, found its way to American patients. 
If the proposed rule to share rebates with consumers at the 
point of sale is finalized, we estimate that seniors taking 
Pfizer medicines could save hundreds of dollars a year, on 
average.
    The second idea is less volume, less pay. Imagine a system 
where Pfizer gets paid based on the number of heart attacks we 
prevent, rather than on the number of pills we sell. In such a 
system, if our medicines do not produce good results, we should 
be paid less. And if they do, we should be paid more.
    Such value-based payment arrangements, if done correctly, 
can align the interests of patients, insurance companies, and 
biopharmaceutical companies around one shared goal, ensuring 
positive health outcomes for patients. I understand that 
several members of this committee are working on legislation to 
pave the way for these types of arrangements. And we applaud 
this effort.
    The third idea is around capping seniors' out-of-pocket 
medicine costs. Patients are increasingly being required to 
take on a disproportionately higher share of their medicines' 
costs. Today patients pay on average 14 percent of the cost of 
their medicines, but they pay only 3 percent of the cost 
associated with hospital stays, for example. This is forcing 
patients to forego taking needed medications or to limit their 
doses. This is bad, not only for patients, but also for overall 
system costs. Patients who do not take their medicines often 
end up in the hospital, costing much more to the system. An 
important first step is capping out-of-pocket costs seniors 
experience in the medical drug program.
    And the fourth idea is to knock down barriers to lower-cost 
biosimilars. Others have spoken about it. Adverse incentives 
that favor higher-cost biologics are keeping biosimilars from 
reaching patients. In many cases, insurance companies declined 
to include lower-cost biosimilars in their formularies because 
they would risk losing the rebates from covering higher-cost 
medicines. I cannot think of a more concerning example of a 
broken system, and we need to do something about it.
    In closing, Pfizer is all about breakthroughs that change 
patients' lives. This is why our more than 90,000 colleagues, 
many of whom work in laboratories and manufacturing plants in 
States represented by members of this committee, come to work 
every day. And it is why we are here today, to work with you 
and all stakeholders to find ways to ensure that we can 
continue to discover medicines that can change patients' lives.
    The Chairman. Thank you.
    [The prepared statement of Dr. Bourla appears in the 
appendix.]
    The Chairman. Now to Dr. Brandicourt.

    STATEMENT OF OLIVIER BRANDICOURT, M.D., CHIEF EXECUTIVE 
                OFFICER, SANOFI, BRIDGEWATER, NJ

    Dr. Brandicourt. Chairman Grassley, Ranking Member Wyden, 
and members of the committee, thank you for the opportunity to 
appear before the Senate Committee on Finance to discuss 
pharmaceutical pricing, affordability, and patient access. I am 
Olivier Brandicourt, the chief executive officer of Sanofi. I 
understand the anger about rising out-of-pocket costs for many 
medicines, including insulins.
    I appreciate the confusion as to why patient costs continue 
to rise, even when the amount that PBMs and health plans pay 
declines. This situation is unacceptable and unsustainable for 
too many patients. My goal today is to have an honest 
discussion about how the system works, and how it can be 
improved. As you may know, 2 years ago Sanofi announced our 
progressive and industry-leading principles.
    First, we made a pledge to keep price increases at or below 
the U.S. national health expenditure projected growth rates. 
Second, we committed to providing a clear rationale for pricing 
when we launch new medicines. And third, we have increased 
transparency by providing each year information about our list 
and net prices across all of our medicines.
    In 2018, the average aggregate least-price increase across 
all Sanofi medicines in the U.S. was 4.6 percent, while the 
average aggregate net price--that is the price actually paid to 
Sanofi--declined by 8 percent. So declining average aggregate 
net price in 2018 represents a third consecutive year in which 
the amount paid by payers across all of our medicines went 
down.
    I feel a special obligation to address the pressing issues 
around access and affordability of our insulins. Insulin is a 
clear example of the growing gap between list and net prices. 
Since 2012, the net price of Sanofi insulins has declined 25 
percent. Yet patient out-of-pocket costs have continued to 
rise. If you take Lantus, for instance, our most prescribed 
insulin, the net price has fallen by 30 percent since 2012. Yet 
over the same period, average out-of-pocket costs have risen 
approximately 60 percent for patients with commercial insurance 
and Medicare. It is my belief that declining net prices should 
result in lower out-of-pocket costs for patients. But clearly, 
this is not always the case.
    Addressing these prices alone will not be sufficient to 
solve the problem of patients' out-of-pocket costs. As we look 
for solutions, we must have protections for patients and link 
responsible pricing to both access and affordability. Every 
actor in the system has a role to play, and Sanofi takes this 
call to action seriously. There are different ways to 
accomplish these goals, and Sanofi could support options that 
align to our core principles. First, changes to the drug 
pricing and reimbursement system must be holistic, factoring in 
all actors in the system. And the majority of benefits should 
accrue to patients.
    And second, to maintain a strong environment for innovation 
in the United States, the government should not directly 
control the price of medicines, either through Federal 
Government price controls, or worse, outsourcing price 
decisions to other countries.
    To ensure that responsible pricing translates to better 
access and affordability for patients, Sanofi supports the 
policy solutions outlined in my written testimony, including 
several policies introduced by members of this committee, such 
as the CREATES Act, the C-THRU Act, and the SPIKE Act.
    So thank you for the invitation to speak with you today, 
and I look forward to answering your questions.
    The Chairman. I thank all of you for your testimony.
    [The prepared statement of Dr. Brandicourt appears in the 
appendix.]
    The Chairman. And I think I heard from each of you that you 
are willing to work with us and people in the administration to 
find solutions to these problems. I welcome that sort of 
cooperation and just implore you that that cooperation will 
have to go on weeks beyond this hearing, because we would not 
expect to get all the information we need just at this hearing.
    Now, we will go to questioning. Do not start my clock yet. 
I have not asked my questions yet. [Laughter.]
    Before I ask questions, if I could have--obviously, we have 
a very important meeting here. We have seven witnesses. We have 
24 or 25 members of this committee.
    I think I am fairly liberal in letting people ask 
questions. But I want to repeat something I have said before, 
and that is that if you will take your 5 minutes, and if there 
are a few seconds left, you ask a question then--hopefully, it 
is a short question at that point, and hopefully there is a 
short answer at that point.
    What irritates me about that process is when somebody 
thinks they can have back and forth for 3 or 4 minutes after 
you ask your last question. So I am asking you, if you would 
please be tolerant towards people who abide by the 5 minutes, 
to be respectful of that so that everybody gets a chance to ask 
questions.
    Now my 5 minutes starts. [Laughter.]
    I want to thank those of you who are here who said you 
would be supportive of legislation that I have been backing for 
a long period of time: CREATES, which is sponsored by Senator 
Leahy and this Senator, and Pay-for-Delay by Senator Klobuchar 
and this Senator. So those are bipartisan bills.
    One other bipartisan bill that you probably do not know 
about yet--it was introduced by Senator Wyden and me a couple 
weeks ago--is called the Right Rebate Act, which would close a 
loophole that was exploited by Mylan in the EpiPen case.
    So leading to my questions, starting off, Ranking Member 
Wyden and I have been working--before I became chairman of this 
committee again, we investigated a lot about Gilead's pricing 
decisions for hepatitis C drugs. During that investigation, we 
acquired a document that listed some factors that Gilead 
considered when it priced those drugs.
    Those factors included the risk of ``public outcry'' or 
``the likelihood of a letter from Congress'' or the 
``likelihood of a congressional hearing.'' So taking off from 
that point, here is a very simple question to answer, I think. 
So I want a ``yes'' or ``no'' from each of you.
    When your company prices its drugs, do you consider the 
risk of negative public opinion in the pricing of that drug? We 
will start with AbbVie.
    Mr. Gonzalez. Senator----
    The Chairman. Can you answer ``yes'' or ``no''?
    Mr. Gonzalez. Yes, we do.
    The Chairman. Yes, you do. Okay.
    What about AstraZeneca?
    Mr. Soriot. Yes, we do, Senator. Amongst other factors, of 
course, but we do.
    The Chairman. Okay.
    What about Bristol-Myers?
    Dr. Caforio. Yes, we do, Senator, among many factors.
    The Chairman. Okay.
    Johnson & Johnson?
    Ms. Taubert. Yes, we do, Senator, as well as affordable 
access to the medicines for the patients.
    The Chairman. Okay.
    What about Merck?
    Mr. Frazier. Yes, we do, among other factors.
    The Chairman. Okay.
    And what about Pfizer?
    Dr. Bourla. Yes, we do, among other factors.
    The Chairman. And what about Sanofi?
    Dr. Brandicourt. Yes, we do, among other factors.
    The Chairman. Okay. Thank you.
    Another ``yes'' or ``no'' question: when determining list 
price, do you consider the likelihood of a congressional 
inquiry? Let's start with AbbVie.
    Mr. Gonzalez. No, we do not.
    The Chairman. What about AstraZeneca?
    Mr. Soriot. No, we do not, Senator.
    The Chairman. What about Bristol-Myers?
    Dr. Caforio. No, Senator, we do not.
    The Chairman. And what about Johnson & Johnson?
    Ms. Taubert. No, Senator, we do not.
    The Chairman. Okay; and Merck?
    Mr. Frazier. Not explicitly.
    I would say we do care what the public thinks.
    The Chairman. Okay.
    And what about Pfizer?
    Dr. Bourla. No, we do not think----
    The Chairman. Okay. What about Sanofi?
    Dr. Brandicourt. Same, Senator; we do not.
    The Chairman. Okay.
    Then I would have another ``yes'' or ``no'' question. When 
your company prices its drugs, do you take into account the 
fact that a key player is the Federal Government?
    Let us start with AbbVie.
    Mr. Gonzalez. We evaluate all the channels when we make 
determinations on price and affordability.
    The Chairman. Okay.
    So that obviously would include the Federal Government.
    Mr. Gonzalez. Correct.
    The Chairman. AstraZeneca?
    Mr. Soriot. Yes, we use the same approach, and of course 
the Federal Government is a very key aspect of our 
deliberations.
    The Chairman. Okay.
    Bristol-Myers?
    Dr. Caforio. Yes, Senator, because the Federal Government 
is a large part of our----
    The Chairman. Okay.
    Johnson & Johnson?
    Ms. Taubert. Yes, we take into account the value to 
patients, the health-care system, and society, and the 
government is a key part of that.
    The Chairman. Okay.
    And Merck?
    Mr. Frazier. Yes.
    The Chairman. Okay.
    And Pfizer?
    Dr. Bourla. Absolutely.
    The Chairman. And then Sanofi?
    Dr. Brandicourt. Yes.
    The Chairman. Okay.
    My last question. ``Yes'' or ``no'': some of you have 
voiced support for the recent rebate rule proposed by the 
administration. Should the administration finalize this rule, 
will you commit to lowering your drug prices?
    Mr. Gonzalez. Mr. Chairman, we are supportive of the rule. 
We would like to see it in its final form, obviously, to make a 
final decision. But we are supportive of taking the discount to 
the patient at the point of sale.
    The Chairman. Okay.
    AstraZeneca?
    Mr. Soriot. The same for us, Senator. I would go one step 
further: if the rebates were removed from the commercial sector 
as well, we would definitely reduce our list prices.
    The Chairman. Okay.
    And Bristol-Myers?
    Dr. Caforio. We have the same position, sir.
    The Chairman. Okay.
    And Johnson & Johnson?
    Ms. Taubert. Yes, we are supportive, and that definitely 
would be my goal. We would just need to see the final 
legislation, provided that there are not additional fees that 
are added into the system to compensate for the rebates.
    The Chairman. Okay.
    Merck?
    Mr. Frazier. I would expect that our prices would go down 
if we change the system, again, on the commercial side as well 
as the Medicare side.
    The Chairman. Okay.
    Pfizer?
    Dr. Bourla. It is our very clear intention that we will not 
keep a single dollar from these rebates. We will try to move 
every single penny to the patients. And we think if this goes 
also to the commercial plans, that would be even better for 
more patients.
    The Chairman. Okay.
    Sanofi?
    Dr. Brandicourt. Lowering list price has to be linked to 
better access and affordability at the counter for the 
patients.
    The Chairman. Okay.
    I want fellow colleagues to know that I stopped at 5 
minutes and 26 seconds.
    Senator Wyden?
    Senator Wyden. Thank you, Mr. Chairman.
    Let me start, if I could, with you, Mr. Bourla, on this 
list price question. And I want to see if we can do a couple of 
``yes'' or ``no'' questions.
    Is it correct that your company, and nobody else, sets the 
starting price for all drugs sold by Pfizer? That is a ``yes'' 
or ``no.''
    Dr. Bourla. It is a negotiation with PBMs, and they are 
very powerful.
    Senator Wyden. But you still get to set the list price?
    Dr. Bourla. Yes, but we set----
    Senator Wyden. Okay.
    Dr. Bourla [continuing]. The list price and the rebates 
based on----
    Senator Wyden. Is it correct when a hypothetical patient--
let us call her Mrs. Jones--goes to pay for her drug at the 
pharmacy counter, her coinsurance is based on the price of the 
drug you set?
    Dr. Bourla. It is correct in many cases.
    Senator Wyden. Okay.
    I just want you all to know that the number one reason 
consumers are getting hammered is because these list prices--
and you have the last word with respect to where they are--are 
unaffordable. And the high prices are tied to what the consumer 
pays at the pharmacy counter. And all this other stuff you talk 
about--the rebates and the discounts and the coupons--all this 
other stuff is window dressing, all of it. And the fact is on 
Part D, 40 percent of the drugs do not even have a rebate.
    So I want it understood--particularly, because I have asked 
you, Dr. Bourla--I think you and others in the industry are 
stonewalling on the key issue, which is actually lowering list 
prices. And reducing those list prices is the easiest way for 
American consumers to pay less at the pharmacy counter.
    Now, Mr. Gonzalez, I want to ask you some questions 
relating to the international pricing situation. Drug prices 
are much higher in the United States than in other developed 
countries, on average 40 percent higher. In 2017, AbbVie made 
$9.9 billion in revenue outside the United States.
    So my first question to you is, do you make a profit on the 
drugs that you sell in Germany or in France?
    Mr. Gonzalez. Yes, we do.
    Senator Wyden. So if you do, and you have said that that is 
the case, if you can turn a profit in a country with 
dramatically lower prices, you can do the same thing in the 
United States. How is that not gouging the American consumer 
with high prices, even though you are giving other people in 
Western industrialized countries a better deal?
    Mr. Gonzalez. Senator, it is a great question. And the 
reality is--and I do not think it is just unique to AbbVie--
that prices vary dramatically around the world. There is no 
question, at least in AbbVie's business for the most part, the 
U.S. has some of the highest prices in the world.
    That is not universally true. The government has some 
relatively low prices in comparison. But I think the 
fundamental issue is this: our system is built around a variety 
of pricing around the world, but that overall system supports 
our R&D model.
    If a market the size of the United States were to collapse 
to the lower end of that pricing model, then I can just tell 
you AbbVie would not be able to invest the level of R&D that it 
invests today. So that is the reality.
    Senator Wyden. Well, I think time is short.
    As I noted in my opening statement, global R&D spending is 
far less than the revenue you make in America. American 
patients bring in more than enough revenue to cover your R&D 
costs.
    I mean, I am going to have town meetings in a few days at 
home, and people will say, ``Ron, this is ridiculous that we 
are getting gouged when people around the world are getting a 
better deal.'' And what you have told me today is: (a) they are 
getting a better deal and you can make a profit; and (b) it is 
somehow tied to research and development. And the fact is that 
research and development is less than the revenue that you are 
making in this country, and that is why people are so angry.
    And I would also like to note that a Humira biosimilar was 
launched in Europe last year, and due to AbbVie's anti-
competitive behavior in the United States, that same biosimilar 
will not be available here until 2023. You have a double 
standard. You are willing to sit by and hose the American 
consumer and give the breaks to people overseas.
    So I am going to wrap up and stick to the chairman's time 
limit by asking you for a response in writing. So that we can 
better understand the situation for the drugs you sell in other 
countries, I would like to know, for the drugs you sell in 
other Western industrialized countries--just the Western 
industrialized countries--does your company make or lose money? 
Can you get that to me in writing within 10 days?
    Mr. Gonzalez. I can give it to you right now.
    Senator Wyden. Okay.
    Mr. Gonzalez. We make money in any country that we sell in 
unless we choose to donate the product into those countries. 
And we do that in certain countries that cannot afford it, but 
not the Western----
    Senator Wyden. I would like it in writing.
    Mr. Gonzalez. Okay.
    One thing I would like to point out that I do not think is 
totally accurate that you described, at least for AbbVie, is we 
spend $5.2 billion dollars in R&D. We make $5.6 billion dollars 
in earnings.
    So our R&D is almost equivalent to what our earnings are.
    Senator Wyden. Well----
    The Chairman. I am going to----
    Senator Wyden. We will continue that.
    The Chairman. I am going to list four names at a time. 
Roberts will be next, and then Stabenow, and then Enzi, and 
then Cantwell. So if you are irritated about how you might be 
on this list, take it out with one of your colleagues on the 
committee, because I am reading it just the way the staff gave 
it to me.
    So, Senator Roberts?
    Senator Roberts. Thank you, Mr. Chairman. I will try to be 
timely.
    This whole situation reminds me of when Mark Twain, i.e., 
Samuel Clemens, went to Missouri--that was his first mistake--
and made some remarks to a small town. The mayor afterwards 
said, ``Well now, we have the tar and the feathers and a rail. 
We would like to ride you out of town on a rail.'' He said, 
``If it was not for the honor of it, I'd just as soon not do 
that.''
    And I think in some ways that is where you are sitting 
right now. I worry about the cost. I worry about the access. I 
worry about the value. I worry about the fact that when I go--I 
did just last night, and all of a sudden I found out that the 
prescription I had cost twice as much. I still have not quite 
figured that out. I do not know which one of you to blame.
    But at any rate, I worry about HHS. I worry about CMS. I 
worry about the Federal Government taking over with regards to 
the decisions that you make. I also worry about what the 
distinguished Senator from Oregon described as a terrified 
public, and certainly we do not want any liars.
    I want to ask you one simple question. Staff has arranged 
about seven good questions. I will submit them for the record.
    Under the banner of certainty and predictability, what 
keeps you up at night? In other words, if in fact we invited 
you back and you could come back--well, let me put it another 
way. What would happen if you ran into some things that were 
unprecedented and you would not be here? We would not have the 
Magnificent Seven, if in fact that's why we won a ``W.''
    What I want to know is, what is the thing that keeps you up 
at night, so you could be a viable company now and down the 
road to achieve what we all want in terms of access and cost? 
And I am going to start with Dr. Brandicourt, because I want to 
go from right to left for a change.
    Dr. Brandicourt. Thank you, Senator. What keeps me up at 
night is ensuring that I have a pipeline of new products which 
is innovative enough to alleviate, you know, some of the 
disease burdens in the countries where we are. So it is making 
our company meaningful and delivering what we are supposed to 
do best.
    Senator Roberts. Thank you.
    Dr. Bourla. Mr. Senator, the reason we exist is to bring 
breakthroughs that change patients' lives. And this is what 
keeps me up, and this is the reason why our employees come to 
work. This is the reason why our investors invest in us.
    If our pipeline will not deliver on the promise--and this 
is very challenging, because you are dealing with very 
difficult diseases to crack--then we will not be able to 
fulfill our promise to society and will not be able to fulfill 
our promise to investors.
    Senator Roberts. Mr. Frazier, thank you for your five-point 
plan. What say you?
    Mr. Frazier. I would say, Senator, the thing that keeps me 
most up at night is the concern that we will not have a viable, 
predictable market that will allow people to continue to put 
the very large amounts of money at risk for a long period of 
time in an attempt to find solutions to some of the hardest 
problems, like Alzheimer's, that have evaded solutions.
    And what really concerns me is when we do not treat these 
issues as systemic issues and the public thinks that they have 
to have outrageous solutions to the problem where, in the 
future, we will not get these drugs.
    So I would hope that we could talk about these things 
systemically and try to come up with the kinds of solutions 
that will, in fact, make patients have access to medicines 
today while allowing tomorrow's breakthroughs to happen. Thank 
you.
    Senator Roberts. Thank you.
    Ms. Taubert?
    Ms. Taubert. Senator, the easy diseases have largely been 
solved. It gets harder and harder as we go after new treatments 
and new cures for ever more challenging diseases.
    So from our perspective, what keeps me up at night is that 
investment in innovation and the ability to continue to invest 
to be able to go after the cures and the diseases that we 
really want to solve.
    Senator Roberts. Thank you.
    Dr. Caforio?
    Dr. Caforio. Mr. Senator, I am a physician, as I said 
earlier. What keeps me up at night is our patients who still do 
not have an opportunity for their cancer to be treated. And as 
a result of that, I am really focused on, first, continuing to 
invest in R&D together with the 7,000 scientists at Bristol-
Myers Squibb, and also making sure that every patient who needs 
one of our medicines has access to it.
    Senator Roberts. Mr. Soriot?
    Mr. Soriot. Senator, two things, actually. One is making 
sure we have the best science, the best scientists, and an 
environment that stimulates their innovation. The second is 
really to come up with ways to demonstrate the value of our 
products. I believe that medicines are actually part of the 
solution, not part of the problem. And it is sad that we are 
talking about those difficulties patients are facing.
    In the last 15 years, the mortality for cardiovascular 
disease has declined by 35 percent. Most of this is due to good 
treatments for hypertension, cholesterol. And in fact, it is 
cost-effective. We keep patients out of the hospital.
    So the one thing that really keeps me up at night is, how 
do we demonstrate the value we bring, and how do we reduce 
overall health-care costs?
    Senator Roberts. Mr. Gonzalez, I am out of time.
    The Chairman. No, he can answer. You asked your question.
    Go ahead.
    Senator Roberts. Thank you for being so liberal. 
[Laughter.]
    Mr. Gonzalez. Thank you, Senator.
    There are two things that keep me up at night. The first is 
we, like many around this table, are working on some of the 
toughest diseases that are out there, which takes on tremendous 
amount of risk--I am sure you heard that many, many times.
    But the reality is, when we work on these diseases, like 
Alzheimer's as an example, when someone comes up with a 
beneficial treatment for Alzheimer's, it is going to change the 
lives of patients, families, and it is going to reduce 
dramatically health-care costs. But not necessarily the cost of 
medicine.
    The cost of medicine is going to go up. The cost of nursing 
homes is going to go down. And systems have a very difficult 
time trying to measure that benefit, but the reality is, when 
you are working in these areas with these kind of intractable 
diseases, that is the ultimate payback that the system has to 
be able to evaluate.
    Senator Roberts. Thank you.
    The Chairman. Senator Stabenow?
    Senator Stabenow. Thank you very much, Mr. Chairman and 
Ranking Member.
    Thank you for being here. I will tell you what keeps people 
in Michigan up late at night. It is the cost of life-saving 
medicine for themselves, their children, their parents. And so 
that is why it is important that we are here, and I am glad we 
are talking about research, because I would like to step back a 
moment and talk about who basically is funding research, and I 
hope you will say ``thank you'' to the American taxpayer, 
because American families fund the National Institutes of 
Health.
    A recent report found that NIH-funded research contributed 
to every single one of the 210 new drugs approved by the FDA 
from 2010 to 2016, and that American taxpayers contributed more 
than $200 billion in grants--$200 billion in grants to your 
companies and others. Grants, not loans; grants to develop 
these drugs.
    That is about 200,000 years of accumulated research. And I 
support that, because the basic research is something that I 
believe we all need to share in. At the same time, when you 
then go from there and are doing R&D, you can write that off 
your taxes, so American taxpayers subsidize you again.
    Now, according to the most recent SEC filings, the seven 
companies--all of you here today--have spent about $80 billion 
on selling, marketing, and administrative expenses last year, 
which was $22 billion more than you spent on R&D.
    So let us just be clear on this: American taxpayers, we are 
happy to help you be able to develop these drugs, but I can 
tell you, people in Michigan just feel that the bargain ought 
to be that they ought to be able to afford the medicine after 
they have helped to develop it.
    Between 2006 and 2015, the largest 25 drug companies 
enjoyed an average annual profit of between 15 and 20 percent. 
Most other large Fortune 500 companies saw between 4 and 9 
percent.
    I know the auto industry would love to get the kind of 
profits that you have. But the reality is that, if people do 
not buy a car, they do not buy furniture, their life is not 
threatened. If they cannot buy your product, it may be. So that 
is why this is so important today.
    And, Mr. Gonzales, I want to specifically start with you, 
because Humira is the world's best-selling drug. It treats 
arthritis, Crohn's disease as we know, also ulcerative colitis. 
And you introduced the drug in 2003, and in 2017 it generated 
$18.4 billion in revenue. And if Humira was its own company, it 
would be among the Fortune 500 companies all by itself.
    So let us talk about this, because the average person on 
Medicare is earning $26,000 a year. The price of your drug 
started high and has gone higher, to a point now where it is as 
much as $50,000 a year.
    So, Mr. Gonzales, your primary patent expired in the U.S. 
in 2016. Is that correct?
    Mr. Gonzalez. That is correct.
    Senator Stabenow. And you have more than a hundred other 
kinds of patents for processes and techniques and so on. In 
fact, according to a report, ``Broad U.S. Humira Patent 
Estate,'' some of the patents go up to 2034, which gives you 
about 31 years of patent protection. That is a pretty good deal 
on this successful drug.
    When we look at what is happening around--well, let me 
first ask this. Has the drug itself gotten any better with all 
the new patents?
    Mr. Gonzalez. I think as you look at the evolution of the 
patent portfolio that is around Humira, it is important to keep 
in perspective that that patent portfolio evolved as we 
discovered and learned new things about Humira, in particular, 
as we discovered that this particular molecule could be 
utilized across a large number of different disease states.
    Senator Stabenow. And I am going to, unfortunately, in the 
interest of time--I appreciate that and would want to follow up 
in writing, but as I understand it, the chemical formula is the 
same. And so it is a question of how we use the patent system.
    But to look at, in Europe, when your patents expired in the 
fall of 2018 and biosimilars came out on the market, your 
prices there were already lower than in the U.S., but now you 
are offering, I understand, up to 80 percent discounts to be 
able to continue to compete in Europe. Why do you not--with all 
of the support from American taxpayers on this drug, why do you 
not offer the same low price to American families?
    Mr. Gonzalez. Because Humira plays a very important role in 
AbbVie's overall funding of R&D. And I think it is 
fundamentally underpinned by the fact that if you look at these 
inventions that we have created, that were patented, as I said, 
they included a number of different diseases for which Humira 
was effective, and they evolved over time.
    We think we have struck a reasonable balance. We have now 
licensed seven biosimilar players to the entire portfolio. So 
they can use that portfolio to go out and copy Humira. We have 
given licenses to them, and they will all enter the market in 
2023.
    The earliest patent to expire in that portfolio is June of 
2022. So, literally seven biosimilars will come within a year.
    Senator Stabenow. Mr. Gonzales, I know my time is up. Let 
me just say, I think that you charge more here because you can. 
And American taxpayers are subsidizing all of you to be able to 
have incredibly high profits, the fastest-growing part of the 
health-care system. And I think the people in Michigan and 
across the country deserve better. They need to be able to 
afford the medicine and not have to go to another country to 
get it.
    The Chairman. Senator Cantwell?
    Senator Cantwell. Thank you, Mr. Chairman.
    I wanted to get feedback on the market-type mechanisms and 
whether they would drive down costs to purchasers and to 
consumers. So concepts like allowing States to negotiate on 
behalf of a population for health-care plans, like the basic 
health plan in New York--do they drive down cost?
    [No response.]
    Senator Cantwell. No one wants to take that on?
    Mr. Frazier. Thank you, Senator. I did not know who the 
question was addressed to.
    I think first of all, it is important to recognize that 
there is no single market for drugs in this country. So for 
example----
    Senator Cantwell. We are on limited time, and I appreciate 
the chairman's great efforts. No, I am just trying to get 
``yes'' and ``no'' answers whether these concepts drive down 
costs--whether you believe they do. If it is a hard question to 
answer, it just tells me something about how willing you are 
going to be to help us with this problem.
    So my point is this. States negotiating on drug prices on 
behalf of a group of citizens, does it drive down prices for 
consumers in your opinion, ``yes'' or ``no''?
    Mr. Frazier. I would have to say, depending on the system, 
it could very well do that. But I think it will do that at the 
expense of a system, for example, our Medicare system that has 
come in at 50 percent of what it was projected to be.
    I want to come back to an issue that was raised at the 
beginning about the affordability, if you will just allow me. A 
significant issue in our system is that patients pay 13 percent 
against the list price for drugs when they pay 3 percent 
against a lower negotiated price for other medical services.
    I think the primary issue in our country now is out-of-
pocket costs--13 percent is much higher than 3 percent. And if 
we were designing a system, we would never design a system that 
actually taxes the sicker people to pay for the healthy people.
    Senator Cantwell. Okay.
    I am asking a really basic question. Like the VA's ability 
to negotiate on drug prices, do you think that States having 
that same ability drives down price?
    Mr. Frazier. I would say that the VA would get a lower 
price and the States would get a lower price if you are willing 
to go into an environment where that could be imposed by 
States.
    Senator Cantwell. Well, or the Federal Government. But in 
one example--which I think you are familiar with, because I do 
think you are involved with hepatitis C drugs--Washington's 
Medicaid program is continuing to think about a Netflix model 
where you buy the best, the lowest per-unit costs, and cover 
more people. Do you think that model works in driving down 
costs to consumers?
    Mr. Frazier. I think that could work to drive down cost to 
consumers, no question, as long as you have the State 
``negotiating.'' I would object to the word. Very frequently, 
when we deal with governments outside the United States, people 
use the word ``negotiations.'' Those prices are imposed.
    Senator Cantwell. Well, someone who is negotiating on 
behalf of the patients they are trying to cover negotiates with 
you or other drug companies on whether they are going to meet 
that discount. They are using market forces of bundling up and 
leverage. I call it a Costco model. If you buy in bulk, you get 
a discount. We are clearly doing it with the VA.
    The question debated here is whether we should spread that 
out to cover more Federal programs, which is what is being done 
in Canada, and whether we should use those same market forces 
in allowing States to negotiate, at least for the working poor 
in this country, a better deal than they can get because they 
work for employers that do not cover them.
    So I think if you guys cannot even agree that these basic 
market functions that allow people to buy in bulk and get a 
discount are good ideas for consumers, then I do not think you 
are going to come up with anything we are going to agree on 
here, because these are market functions, basic market 
functions.
    Does anybody else want to add whether they believe in these 
market functions?
    Mr. Gonzalez. Yes, Senator. I would just illustrate one 
point.
    I think your point is a valid one for the overall system 
costs, but I think what Mr. Frazier was describing is a 
critical issue.
    There are two affordability issues here. There is the 
affordability to the system, and there is the affordability to 
the patient. Both have challenges, but the affordability to 
patients now has really gotten out of hand.
    I will give you an example, my HCV example. We cut the 
price by 72 percent, the list price by 72 percent. The out-of-
pocket cost in Medicare is $3,250. The same patient who could 
not afford the out-of-pocket cost at $7,000, unfortunately 
cannot afford $3,250.
    Senator Cantwell. Well, I will tell you what is absurd is 
the fact that you got a $6.3-billion tax break in the last tax 
bill and you cannot even say that you are for basic market 
functions like giving people discounts when they are bundled 
and you get volume.
    So I guess we will have a tough time coming to something--
but I know people here are going to want basic market functions 
to drive down costs for consumers.
    Thank you, Mr. Chairman.
    The Chairman. Senator Cornyn?
    Senator Cornyn. Thank you, Mr. Chairman.
    Mr. Gonzalez, I want to focus on Humira. Obviously it 
generates about $18 billion of revenue for your company each 
year. Is that right?
    Mr. Gonzalez. That is correct.
    Senator Cornyn. Please understand that I get it. We want to 
make sure that we maintain the most innovative pharmaceutical 
drug companies in the world, because we want to provide 
lifesaving cures for our people. And I get the idea that that 
is the purpose of the patent system, which is to protect the 
exclusivity of that drug that you have sunk a lot of money into 
the research and development for. And I support our patent 
system. I think it is very important.
    But what I do not understand is, according to my 
information here, Humira has 247 patents. And some of those 
patents do not expire until 2034. As Senator Stabenow pointed 
out, Humira first was sold to patients in 2003.
    So is it your company's position that it should have an 
exclusive monopoly on that medication for 31 years?
    Mr. Gonzalez. Senator, no, it is not. It is essentially 
that the patents cover innovations that we created. And I think 
one of the things that has been lost here is, it does not 
matter how many patents you have--and those are applications 
that you described, not actual patents. But there is a large 
portfolio of patents. It has 136 patents, and together----
    Senator Cornyn. So you have 247 patent applications, but 
you have 61 patents? How many patents do you----
    Mr. Gonzalez. No. I am sorry. A hundred and thirty-six 
patents.
    Senator Cornyn. A hundred and thirty six patents on one 
drug?
    Mr. Gonzalez. But well, remember, Humira is like 9 
different drugs or 10 different drugs. So----
    Senator Cornyn. I thought you said to Senator Stabenow it 
was the same molecule.
    Mr. Gonzalez. It is the same molecule, but it treats 
different conditions. And if you look at that patent 
portfolio----
    Senator Cornyn. So you use the same molecule to treat 
different conditions, and you can get a patent on that 
treatment?
    Mr. Gonzalez. Certainly. Now, an example of one of the 
areas that got a significant number of patents is inflammatory 
bowel disease. After we developed it for RA, we realized that 
Humira might work in that area. That was an area that was 
under-treated. Most drugs had failed.
    We did 20 clinical trials to determine how to make Humira 
work in those patients. And we were issued a large number of 
patents for the discovery work that we did in that area.
    But in the end, the number of patents is not something that 
protects a product. If a competitor wants to make a generic 
version of a product--there are patents everywhere. The 
question is, does the invention stop the biosimilar player from 
making the product? If the invention does not, the patent is 
meaningless. If the invention and----
    Senator Cornyn. The patent gives you an exclusive right to 
produce a drug.
    Mr. Gonzalez. No, we do not block any biosimilars. 
Biosimilars can make the product----
    Senator Cornyn. No, no. Maybe you misunderstood. A patent, 
during its term, gives you exclusive rights to produce a drug. 
Correct?
    Mr. Gonzalez. No.
    Senator Cornyn. No?
    Mr. Gonzalez. No. The composition-of-matter patent would 
give you exclusive rights to produce the drug. But the patents 
that are covered in this portfolio are for individual 
innovations that were created. And in many cases, when we go 
into an area, there are always patents. The first thing you do 
is, you look to see, can I design around those patents?
    If ultimately you determine you cannot design around those 
patents, then you go to the player who has the patent and you 
negotiate a license. And we have now given license to virtually 
every single biosimilar player--with the exception of one--and 
we have done it literally 10 years before the last patent 
expires in that portfolio.
    So we have tried to strike what we think is a reasonable 
balance. I realize it may not be popular, but I think it is a 
reasonable balance. Those----
    Senator Cornyn. But what I am concerned about is--as I told 
you at the outset, I support drug companies covering a profit, 
based on their R&D and their development of innovative drugs. 
But at some point, that patent has to end, that exclusivity has 
to end so that the patients get access to those drugs at a much 
cheaper cost.
    It is true that you, your company, blocked Amgen for a 
number of years from seeking to produce a Humira biosimilar or 
equivalent; correct?
    Mr. Gonzalez. Amgen has a license in the United States 
right now to be able to produce----
    Senator Cornyn. But you blocked them for 5 years, right?
    Mr. Gonzalez. No, we did not block them.
    Senator Cornyn. You sued them.
    Mr. Gonzalez. They came to us, and they wanted access to 
the portfolio that we had. And we licensed them.
    Senator Cornyn. Did you sue them?
    Mr. Gonzalez. We did, yes.
    Senator Cornyn. And you entered into an agreement with them 
that accommodated both your needs and their needs, I assume.
    Mr. Gonzalez. We licensed them a patent portfolio. They pay 
us a royalty on the patent portfolio when they come to market, 
and that is essentially just like any other license.
    Senator Wyden. Mr. Chairman, I do not want to interrupt. 
Senator Cornyn is dead right, and that is exactly the same 
point I was going to make.
    Senator Cornyn. Mr. Chairman, could I just make a 
suggestion that----
    The Chairman. Go ahead.
    Senator Cornyn. I know this topic is within the 
jurisdiction of the Finance Committee, but those of us like you 
and me who are also on the Judiciary Committee, which has 
jurisdiction over the patent system, I think this is an area 
that we need to look into through our Judiciary Committee 
authorities as well.
    The Chairman. Why don't you take that up with Senator 
Graham, and I will make sure that I back you up on it.
    Senator Cornyn. I will look forward to your back-up.
    The Chairman. And let me know what your conversation 
produces.
    Senator Cornyn. Thank you.
    The Chairman. The next four would be Menendez, Thune, 
Carper, and Isakson.
    Senator Menendez?
    Senator Menendez. Thank you, Mr. Chairman.
    Let me say a few words before asking some questions. To the 
New Jersey companies here today, thank you for coming. I am 
proud our State is at the forefront of innovation.
    But even in New Jersey, where the pharmaceutical industry 
and related fields like medical research employ hundreds of 
thousands of people, the overwhelming majority of the more than 
9 million New Jerseyans believe drug prices are too high. And 
so I think we all have to be responsive to that challenge 
collectively.
    Americans everywhere reject the notion that reducing 
prescription drug costs means reducing innovation. They are 
uniting around this issue. And it is not a Democratic or 
Republican priority. It is bipartisan. Maybe it is for 
political reasons, but President Trump is talking more and more 
about executive action.
    A Republican chairman of the Finance Committee, Senator 
Grassley, has convened this hearing today, the second of two on 
prescription drugs. And reducing prescription drug prices has 
become a focal point of virtually every Democratic presidential 
campaign.
    So consider it a friendly warning from someone who believes 
in the hope that you provide patients in need of new cures and 
treatments: it is time to be proactive, because if you do not 
make the meaningful action to reduce prescription drug prices, 
policymakers are inevitably going to do it for you. So I just 
hope you will take that to heart.
    Let me ask you, many corporations--not just pharmaceutical 
ones--received a huge windfall from the Trump tax bill. Your 
companies spent well over $40 billion buying back your own 
stock in the past year. Going down the row, can you just give 
me the ballpark number? Did any of you use your tax breaks to 
lower the costs of any of your prescription drugs?
    Mr. Gonzalez. We did not use our tax break to lower the 
cost of prescription drugs. We used it for other aspects of 
trying to stimulate the economy and invest further in the 
United States.
    Senator Menendez. No, you did not use it to lower the cost.
    Mr. Soriot. Senator, the tax break for us, being based in 
the UK, had a very marginal impact on our profitability. So I 
think the question is----
    Senator Menendez. The question is--it is a simple ``yes'' 
or ``no.'' Whatever the tax break was, did you use any part of 
it to lower the cost of prescription drugs?
    Mr. Soriot. Well, the cost of our prescription drugs on the 
net basis has been declining for many years now. Senator Wyden 
took----
    Senator Menendez. I am sorry to interrupt you, Mr. Soriot. 
It is a simple question. Did you use any part of the tax break 
that you got to lower the cost of your prescription drugs?
    Mr. Soriot. In a roundabout way, yes, we did, because the 
minimal tax benefit we got helped us sustain our profitability 
at the same time as our prices were declining.
    Senator Menendez. Dr. Caforio?
    Dr. Caforio. We did not.
    Ms. Taubert. Hello, Senator. It provided us the opportunity 
to invest an incremental $30 billion in R&D and capital 
investments in the U.S. over the next 4 years. We think that 
that is the best way for us to be able to deliver for patients.
    Senator Menendez. Mr. Frazier?
    Mr. Frazier. Senator, our effective tax rate went up from 
19.1 to 19.8 percent.
    Dr. Bourla. We did use this tax break to do many things, 
among them reduce our prices. Prices in 2018, for the first 
time since I remember, went down at Pfizer.
    Dr. Brandicourt. As a French company headquartered in 
Paris, we did not get much from the tax break. On the GAAP 
basis, we lowered our global tax rate by 1.5 percent.
    Senator Menendez. All right.
    Now, in November 2017, FDA Commissioner Scott Gottlieb 
called on pharmaceutical companies to ``end the shenanigans 
when it comes to the ability of potential competitors to 
purchase branded doses at full market price.'' He stated, ``I 
see this clearly, for example, in steps branded companies 
sometimes take to make it hard, or altogether impossible, for 
generic firms to get access to the doses of the branded 
companies needed in order to complete bioequivalence studies 
that the FDA requires for a generic approval.''
    I have co-sponsored legislation called CREATES that ends 
the gamesmanship by certain companies, where they prevent 
generic manufacturers from accessing the necessary samples they 
need to develop generics. Last year the FDA published its first 
list of medicines that generic companies have had trouble 
accessing. That list includes more than 170 complaints covering 
50 medicines.
    So can you go down the line and tell me, ``yes'' or ``no,'' 
does your company in any way restrict access to, or block the 
purchase of samples at full market price?
    Mr. Gonzalez. No, we do not.
    Mr. Soriot. No, we do not.
    Dr. Caforio. We do not. We support the current version of 
the CREATES Act.
    Ms. Taubert. No, we do not.
    Mr. Frazier. No, we do not.
    Dr. Bourla. No, we do not, and we support CREATES.
    Dr. Brandicourt. No, we do not, and we support CREATES too.
    Senator Menendez. I have other questions. I am going to 
submit them for the record. Thank you.
    The Chairman. Thank you.
    Senator Carper?
    Senator Carper. Thanks to each of you for joining us today. 
My wife lost her mother when she was 11 years old. My wife said 
it put a hole in her heart. She has never gotten over it. My 
own mother, her mother, and her grandmother, by the time they 
were 80, they did not know who they were, or where they were, 
or who we were.
    For all of us this is personal, and it is political, and it 
is economic. When we have a hearing of this nature, one of the 
things I like to do with disparate witnesses like these--you 
are all from the same industry, but you have different views, 
come from different parts of the world. But I am going to, in a 
minute, give you--what I am looking for is consensus. What I 
think we are looking for is consensus agreement on what is the 
right thing to do to make sure that what we are producing is 
effective and affordable for us, for the government, for our 
constituents.
    I am going to give you three items and ask you to tell us 
what you think. If we do nothing else, those three items, we 
can all agree on those. Okay, and I will give them to you right 
now.
    The first is eliminating rebates to PBMs. That is the first 
one: eliminating rebates to PBMs. The second is value-based 
arrangements. And the third is increasing transparency 
industry-wide on how you set your prices--increasing 
transparency industry-wide on how you set your prices.
    If you would like to take a moment--and we would just start 
with you, Mr. Gonzalez. We will just start with this question 
first and see if we have time to get it done. I hope we do, 
those three.
    Mr. Gonzalez. I would say that we clearly support providing 
the discount at the patient level, so eliminating rebates, 
essentially.
    We absolutely support value-based pricing, because that is 
the business we are in and the kinds of diseases we are trying 
to treat and cure.
    And we absolutely support transparency. And I would say 
transparency even more broadly across the entire system, 
including everyone that is in the supply chain. And that would 
also include where government rebates are, such as the 340B 
program. We would support total transparency across that.
    Senator Carper. Thank you. I would ask each of our other 
witnesses to also keep your responses short.
    Mr. Soriot?
    Mr. Soriot. Senator, I would give the same responses. We 
support all three items.
    I would go one step beyond, which is if the rebates--as I 
said earlier--were to be removed from Part D and the commercial 
sector, we would actually reduce our list prices by the 
rebates' amount, less the fees that are probably single-digit 
type fees to be paid to wholesalers and other stakeholders in 
the system.
    Since you talked about a disease that is very common and 
becoming more common and a tragedy for people who suffer from 
it, Senator, I would just like to say that, as Mr. Frazier said 
a bit earlier, his company spent a billion dollars on 
developing a drug for Alzheimer's. Our company together with 
Lilly, we spent $900 million to try to develop an Alzheimer's 
drug that failed.
    And that is a really good reminder of the risks that we 
take as an industry. We spent $900 million, many years of work, 
and at the end of the day, nothing.
    Senator Carper. Thank you.
    Dr. Caforio?
    Dr. Caforio. Yes, Senator. First of all, I am very sorry--
--
    Senator Carper. Please be very brief.
    Dr. Caforio. I would say that not only do we support all 
three elements that you mentioned, but I do believe those three 
elements together with the continued effort to develop a 
generic and biosimilar market would mean significant change, 
and would clearly alleviate the concerns that patients have 
today.
    Senator Carper. Great. Thank you, sir.
    Ms. Taubert?
    Ms. Taubert. Senator, first of all, I am very sorry for 
your wife's family and also for your family. It underscores----
    Senator Carper. While I said that, everybody in this room 
could probably point to similar experiences. All of us have had 
them.
    Ms. Taubert. Absolutely.
    Senator Carper. Thank you.
    Ms. Taubert. We are very supportive of all three elements 
that you outlined. So the elimination of----
    Senator Carper. That is all I need.
    Ms. Taubert. Perfect.
    Senator Carper. Thank you.
    Mr. Frazier?
    Mr. Frazier. We too support all three.
    Senator Carper. Thank you.
    Dr. Bourla. Senator, all three elements are 
transformational for our industry, will disrupt it. However, we 
do agree that these are the three things that need to be done, 
and also I believe that they will have significant, meaningful 
results if we do them.
    Senator Carper. Thank you, sir.
    Dr. Brandicourt. We strongly support the three, Senator, 
but we want to keep in mind at the end of the chain, the 
patient has to benefit. So if rebates are removed, it has to be 
to the benefit of patients.
    Senator Carper. Good. Thanks.
    Mr. Chairman, I am going to do a follow-up question in 
writing, asking your responses, your reaction to what is going 
on in Germany on this front--what do you like about it, what 
concerns you might have about it. But that is a different 
question, but it relates to this discussion.
    Thank you.
    The Chairman. Before Senator Thune goes, can I ask Dr. 
Caforio, did you say you support the CREATES Act as well?
    Dr. Caforio. I did, Chairman Grassley.
    The Chairman. Thank you. As sponsor of that, I appreciate 
that very much.
    Dr. Caforio. Thanks for your work in that area.
    The Chairman. Senator Thune?
    Senator Thune. Thank you, Mr. Chairman.
    I would like to ask unanimous consent to insert for the 
record a one-page document from 340B Health that shows that 
manufacturer discounts account for less than 2 percent of the 
total drug market.
    The Chairman. Without objection, so ordered.
    [The document appears in the appendix on p. 1,053.]
    Senator Thune. Thank you.
    Each of you has referenced the recently proposed rebate 
rule, which outlined several different scenarios of how drug 
companies and others would react, as well as the impact on Part 
D premiums.
    Mr. Frazier and Dr. Bourla, if the rule were finalized, 
could you please discuss how you would set list price and how 
your negotiations would work with others in the supply chain?
    Mr. Frazier. Okay, assuming that--as I said when I answered 
the question before, assuming that we do change the systems on 
the commercial side and the Medicare side so that no one 
company faces a disadvantage, we would be lowering list prices.
    We have been asked to lower list prices. We have lowered 
list prices in the past and found that it creates a financial 
disadvantage for the company, and it does not get us more 
volume because of the incentives in the system. So if we change 
all the incentives at one time, then list prices can come down.
    Senator Thune. Dr. Bourla?
    Dr. Bourla. Fifty percent of the American people are in 
commercial plans, and these rebate rules apply to Medicare. If 
the rules apply to all, definitely the list price will go down.
    But also, during the Medicare-only application, we pledge 
and we commit that every single dollar will go to the patients.
    As the chairman said, the list price is not irrelevant. It 
is very relevant for a lot of people, because they have to pay 
list price during the deductible period. However, if the rebate 
rule is applied, then it becomes irrelevant because the 
patients will not be paying the list price at the purchase 
point. And this is a significant win.
    What I want to say is that, even if we do not move it to 
commercial, which I overwhelmingly support, I think it is a 
significant win for the American people if we do it even in 
Medicare only.
    Senator Thune. So Medicare-only would be an improvement, 
but you pointed out in your testimony the challenges associated 
with the bifurcated market with respect to rebate reform. So 
how would manufacturers respond if the rebate rule were 
finalized for government programs? I mean, what does that mean 
for the commercial market?
    Dr. Bourla. Senator, as I said before, all these proposals 
we are discussing, including eliminating the rebate rule, are 
transformational and will disrupt the way we do business. I do 
not know exactly how the system will evolve, and I really do 
not favor a bifurcated system. I would like to have a 
transparent, single system across both parts. So we need to see 
how the whole thing will evolve.
    Senator Thune. Okay.
    You have each expressed support, and this was alluded to 
earlier by Senator Carper, for paying for value as well as the 
value your medicines bring to the health-care system. I am a 
believer in value-based insurance design as a way to lower the 
overall health-care costs, and I have worked on legislation to 
advance this principle.
    As we drive toward paying for value, how do we make sure 
that you as drug manufacturers still have the incentives to 
keep your prices low and that we are not just shifting money 
around in the system?
    Dr. Bourla. I think by definition that a value-based 
arrangement will align the incentives, not only of us, but 
those of the insurance companies, around one common goal: the 
good for the patient, clinical outcomes, measurable clinical 
outcomes for the patient and the health-care system.
    In this case, if we fail to produce drugs through our 
research efforts that will have meaningful clinical benefits 
for the patients, yes, we will not be paid. And this system 
also will ensure the medicines that do not add value will be 
paid much much less. So to create space for medicines that do 
create value is the best way of aligning the incentives of 
everyone around the interest of the patients.
    Senator Thune. Does anybody else want to react to that?
    Mr. Soriot. Yes, Senator, if you allow me.
    We have an example that I quoted before. We have a product 
that is used for the treatment of patients who have experienced 
a heart attack.
    If you experience a heart attack, when you are discharged 
from the hospital, your chance of getting a second heart attack 
is pretty high. So we contracted with an organization and 
committed to reducing the percentage of patients who have a 
second heart attack.
    In return, the University of Pittsburgh Medical Center, for 
these Medicare patients, committed to ask these patients to pay 
a very low co-pay to make sure they were complying with their 
treatment. And that actually delivers value to the system, 
because patients are kept healthy. Of course, good for them, 
but also they do not go back to the hospital. This is how we 
deliver value.
    Senator Thune. Okay. Thanks.
    Mr. Gonzalez. Senator, I would just add one point. I think 
your point is a valid one. Look, an innovative pharmaceutical 
cannot capture 100 percent of the value that it saves. It has 
to capture less than that.
    And I think the way that will evolve the best is if there 
is strong market competition. I remember back in HCV, if you 
look at the health economic data around that drug, it would 
have suggested that you could justify a price well north of 
$100,000 per patient. And the prices were relatively close to 
that when there was one player in the market. Today prices have 
gravitated down to about $25,000-$26,000 per patient.
    It is the market force that created that, the market 
competition of more than one player being in that market and 
competing on an active basis. We were obviously part of that 
competition that drove those prices in that direction.
    So I do not think it is realistic to assume that a 
pharmaceutical, just because it can save $150,000, as an 
example, that it can charge $150,000. It has to charge less 
than that so that the overall system can benefit from the value 
of that medicine. But it has to be able to charge a price that 
is reasonable enough to be able to achieve and continue to fund 
the programs going forward.
    The Chairman. Senator Isakson, and then Senator Cardin.
    Senator Isakson. Thank you, Mr. Chairman.
    I thank all of you for being here. This is a terrific 
hearing, and we are going to have a lot of hearings on this 
subject. I told my staff a couple of weeks ago, I said, ``You 
know, I have been a solid supporter of the pharmaceutical 
industry all my career,'' and I have, and I appreciate all that 
you do.
    I go to work every day because of levodopa. I would not be 
able to be here today if it was not for the pharmaceutical 
industry, and I have Parkinson's disease. But I can function 
every day and do my job because of that, and I appreciate it 
every day.
    My first chief of staff called me Sunday night from 
Children's Hospital in Atlanta to say his youngest son had just 
been diagnosed with juvenile diabetes. His first child, a 
daughter, had juvenile diabetes 12 years ago. But the thing he 
said was, ``At least I know that you can live a normal, happy 
life because of insulin and because of pharmaceutical care.'' 
So I am not softening you up, but I am softening you up, 
because those are good stories that we cannot forget. And that 
is the value of innovation and research development, and we 
appreciate it.
    However, when you cannot explain it and you are elected to 
the U.S. Senate--and I appreciate your comment about how 
honored you are to be in the U.S. Senate, Dr. Bourla--but the 
fact of the matter is, when I cannot explain it, it is tough. 
And I cannot explain the cost increases I have seen a lot of 
recently.
    One medicine I take--I take eight a day--one of the ones I 
take every day went up. When I went to get my new prescription 
in January, it was $90 more than it was at the end of last 
year.
    I just said, ``How can that be?'' And the guy said this and 
that and the other. But he said, ``Let me call you back.'' He 
said, ``I will call you in the next hour and see if I cannot 
find a better price.''
    In an hour's time he had four prices for the same 
pharmaceutical. If I did not use insurance, it was one price. 
If I used cash, it was another price. If I took discounts, it 
was another price. If you had coupons, it was another price.
    I do not remember the name of all of them, but I know it 
was very complicated, and it reminded me of my business. When I 
sold real estate, the price of a mortgage was not just the 
interest rate that you paid and the sticker price, but you take 
the effect of discount points and rebates and other things that 
go into the annual percentage rate return of the product, and 
that is what you are doing with discounts and with rebates, I 
assume. And it is going into the cost and ultimately into your 
product, which caused me to ask this question: who sets the 
discount and who sets the rebate?
    Pardon my finger. We will start with you, Mr. Gonzalez.
    Mr. Gonzalez. Thank you, Senator.
    I think the best way to illustrate what you are describing 
is to give you an example.
    Senator Isakson. A short example, please.
    Mr. Gonzalez. Okay.
    Humira--we raised the price in 2019 6.2 percent. The actual 
fall-through to the company, the realized increase in 2019, 
will be .9 percent. So the part in between there is rebates 
that have gone up and channel mix, primarily. But it does give 
you some idea of the massive change that can occur between list 
and realized price.
    We raised the price to try to offset inflation, merit 
increases that we give our employees, and increases in R&D----
    Senator Isakson. So you set the discount or the rebate?
    Mr. Gonzalez. Well, we negotiate with payers. So managed 
care----
    Senator Isakson. You are a supplier, though. So you 
negotiate with the PBMs and those people? Is that right?
    Mr. Gonzalez. Correct, and they negotiate aggressively.
    Senator Isakson. Is that pretty much true, everybody, that 
they are the major component between the end retail consumer 
price and the origin of the product?
    Mr. Gonzalez. Yes, Senator.
    Senator Isakson. Well, that seems like some place we ought 
to focus, because that is where the distorted numbers come in.
    Johnson & Johnson--and I'm sorry. Janssen, is that right? 
Is that the subsidiary?
    Ms. Taubert. Yes, Janssen; correct.
    Senator Isakson. In your testimony you talk about your 
average list price of 8.1 percent up, but an average net price 
change of only 4.6 percent. So, while your gross went up 8.6, 
your net went down 4.6 in the same pricing period.
    How does that happen? How does it not go up on the bottom?
    Ms. Taubert. Yes, and in fact in 2018, our net price 
actually declined 8.6 percent, so even more than that. So the 
intermediaries in the system are very very effective 
negotiators.
    Senator Isakson. Tell me who the intermediaries are.
    Ms. Taubert. Those would be the PBMs and the insurers.
    Senator Isakson. And the insurance companies?
    Ms. Taubert. Right, and they set the formularies for 
patients.
    Senator Isakson. And they are not the same, because they 
are two different people?
    Ms. Taubert. Yes, correct.
    And so what they do----
    Senator Isakson. Excuse me for interrupting Ms. Taubert. I 
want to make sure I get all of this in. And I apologize. You 
are a nice lady, and I am being ugly to do that. But I am 
sorry.
    Ms. Taubert. I am fine.
    Senator Isakson. All right. We have the PBMs and we have 
the insurance companies.
    Ms. Taubert. Yes.
    Senator Isakson. Is there anybody else between the 
wholesale price by the manufacturer at the beginning and the 
retail price it is sold for at the end, at the drugstore? Is 
there anybody else that contributes to the cost, other than the 
discount and the rebate?
    Dr. Brandicourt. Several actors, Senator, in the supply 
chain are rewarded on the listing price: wholesalers 
themselves, and----
    Senator Isakson. Is that a consumption bonus? Is that a 
sales bonus? They are rewarded for doing what?
    Dr. Brandicourt. Well, to be a wholesaler and distribute 
our products. What we need to do in order to realign the 
incentive is to get rid of the reward being based on a listing 
price.
    Senator Isakson. I have to stop, because the chairman is 
mean and he will cut me off the next time.
    So I will end by saying this. You answered my question, but 
it does point out that the one person who is not benefiting 
from the rebates, not benefiting from the cost negotiation, is 
the customer. And we are here for the customer today. We 
represent them. So we have to get to the bottom of this so we 
can have something we can explain, and they can experience.
    I apologize, Mr. Chairman.
    The Chairman. I let the Senator go because he was echoing 
my beliefs.
    Go ahead, Senator Cardin.
    Senator Cardin. Thank you, Mr. Chairman. And let me thank 
all of our witnesses. I also want to say how proud I am of the 
results of the pharmaceutical industry and the discoveries that 
you have made, innovations that you have brought to market, the 
impact you have had on quality of life and on cost, overall 
cost of health care, by the discoveries that you have been able 
to advance.
    The challenge that we all have is, why should Americans be 
shouldering the lion's share of the cost and burden of research 
and development and bringing new drugs to market? You talk 
about burden-sharing, you talk about the fact that there should 
be a fair allocation on the global market--and by the way, also 
within our domestic market, we know that a lot of people are 
being denied access to these innovative drugs because of the 
pricing mechanisms within the United States.
    So let me try to drill down on those points. Really, am I 
defending an administration policy? So let me break with my 
normal tradition and talk about the international pricing 
mechanism that the Trump administration is proposing that would 
set target prices or international pricing indexes over a 5-
year period for Part B drugs pinned to the price in comparable 
industrial nations, phasing it in over a period of time and 
allowing a cushion for even higher prices in the United States.
    So if, in fact, these drugs are already priced 
competitively, that should not be a problem. But as I 
understand it, there are so many drugs that we pay, American 
consumers pay, a lot more for than consumers in other 
industrial nations. So why not move towards a process in which 
American consumers share a similar price as consumers in other 
industrial nations in the world, particularly on the Part B 
program? I think it could also be extended to Part D.
    The only explanation I have heard is that in some 
countries, it takes a little bit longer to get new drugs 
admitted. We are not talking about new drugs. We are talking 
here about drugs that already have an existing price mechanism. 
Or do you support it?
    Dr. Caforio. Senator, thanks for your question.
    I did mention this in my opening remarks. So I am happy to 
elaborate further. I think it is a very important point.
    So we take the perspective that we should always start from 
patient access to medicines.
    Senator Cardin. I am going to try to drill down, because I 
only have 2 minutes.
    Dr. Caforio. Thank you.
    Senator Cardin. So what is wrong with a model of comparing 
U.S. prices to prices in other industrial nations?
    Dr. Caforio. So 55 percent of new cancer medicines that are 
available to American patients are not reimbursed in at least--
--
    Senator Cardin. We are talking about where there is a 
market price in another country, because if there is no target 
price, there is no price to compare it to. So there has to be a 
price in another country. So we are talking about drugs that 
are commonly available.
    Dr. Caforio. I believe, Senator, many of the most recently 
introduced drugs are not available in----
    Senator Cardin. Then that would not apply. If I understand, 
it only deals with prices where there is a target price that 
already exists. If the drug is not on the market, it is not 
going to have a target price. But if the drug is on the market, 
you have a target price, and as I understand it, that would 
bring down the cost here in the United States.
    Dr. Caforio. I believe, Senator, it would be very important 
for us to be thinking about policies that continue to reward 
innovation.
    We do need your support to make sure that----
    Senator Cardin. So you are basically saying we overpay on 
available drugs so that you can make more profit from the 
American consumer to underwrite R&D which benefits the global 
community. That is basically, as I understand that point--to me 
that is a disconnect in the pricing mechanism.
    I want to ask, Ms. Taubert, you are the one who mentioned 
the advantages of the free market in negotiations under Part D. 
So let me just change the equation. Suppose you were on the 
other side of the table. Why not allow the Health Secretary to 
combine the entire Medicare market in order to negotiate a 
larger market share to bring down costs for Medicare?
    Ms. Taubert. Yes, so we really believe that open 
competition and a free market are the right way to go for 
patients.
    Senator Cardin. But isn't market share that you can offer, 
as a person seeking the cost, a driver for bringing down costs?
    Ms. Taubert. So the PBMs and the insurers are 
extraordinarily effective negotiators. And they do negotiate 
now on behalf of Part D members quite aggressively.
    In fact, I mentioned our $21 billion----
    Senator Cardin. And my question is, is it not true that the 
larger the market share, the better the price you are going to 
get?
    Ms. Taubert. The larger the market share, the better the 
price? It depends on a number of factors, including the number 
of competitors and the companies that are bidding to try to 
get----
    Senator Cardin. If you control more of the market, isn't 
that going to bring down your price? I learned that in 
Economics 101.
    The Chairman. Answer the question, and then we will go to 
Senator Hassan.
    Ms. Taubert. Yes; I am not sure I understand the last piece 
of that question.
    Senator Cardin. With a larger consumer base on a drug, 
because you represent all the Medicare market, are you not in a 
stronger negotiating position? Yes, you are.
    Ms. Taubert. I think conceptually you could be. I would say 
that the PBMs and insurers are pretty darn effective right now.
    The Chairman. Senator Hassan?
    Senator Hassan. Well, thank you, Mr. Chairman. And I want 
to thank you and Ranking Member Wyden for this hearing today.
    I want to thank all of the witnesses for being here today 
as well. A couple of observations; one is that breakthroughs 
are not breakthroughs if people cannot afford the medicine that 
produces the breakthrough.
    Secondly, as you have all mentioned the importance of a 
viable and predictable system, it has to be a viable and 
predictable system for patients. And right now it is so 
convoluted and so non-transparent that my constituents cannot 
figure out what the price of their medication is going to be 
day to day. And despite a wonderful staff, I feel like I need a 
Ph.D. in prescription drug pricing to understand how the heck 
this industry works. And that should not be the way we proceed 
in this country to get these breakthroughs to people.
    But I want to talk about a slightly different aspect of 
your industry right now. We have been talking about drug 
pricing, which is one part of how drug companies make money. 
The other part is how you maximize sales.
    So, Ms. Taubert, I would like to focus on how your company 
maximizes sales for a particular class of drugs--opioids. Can 
you define for me please, Ms. Taubert, what pseudo-addiction 
is?
    Ms. Taubert. I am sorry. I am not sure. I am not familiar 
with that term.
    Senator Hassan. Let me fill you in, then. Pseudo-addiction 
is an unproven and dubious concept that asserts that certain 
patients present signs of addiction because they were 
prescribed insufficient doses of opioids. Those peddling this 
pseudo-addiction concept say that instead of providing 
addiction treatment when somebody shows the signs of addiction, 
the doctor should increase their opioid doses. Even one of the 
original doctors who pushed this theory now admits it was ``an 
excuse to give patients more drugs.''
    He has told us that Janssen promoted this made-up concept 
of pseudo-addiction on a website that it approved and funded 
that was called ``Let's Talk Pain.'' Since then, your company 
has repeatedly said that your action ``in the marketing and 
promotion of our opioid pain medicines was appropriate and 
responsible.'' So, Ms. Taubert, how can you possibly claim that 
promoting the theory of pseudo-addiction--the doctor should 
prescribe more opioids to patients showing signs of addiction--
was appropriate and responsible?
    Ms. Taubert. Senator, thank you so much for that question. 
Abuse and addiction, particularly opioid abuse and addiction, 
are very serious public health concerns, and we recognize the 
impact on the American public.
    Senator Hassan. So then the question is--and again like 
everybody else, I have only a few minutes here. The question 
is, looking back at what your company did promoting pseudo-
addiction--an unproven theory that was just used to maximize 
sales of a deadly drug--why is that something that you are 
calling appropriate and responsible?
    Ms. Taubert. So, I am sorry. I am not familiar with the 
term.
    What I can say is, on behalf of our company, opioids 
represent less than 1 percent of our product.
    Senator Hassan. All right, let me stop you right there, 
because my constituents do not care about the percentage. They 
care about the behavior to maximize sales in an industry.
    Do you know how many Americans died from drug overdoses in 
2017?
    Ms. Taubert. Far too many.
    Senator Hassan. It was 70,237. In 1 year, more Americans 
died from drug overdoses than died fighting the entire war in 
Vietnam. And the vast majority of those overdose deaths, about 
50,000, were from opioids.
    My constituents are dying. Nearly 500 people in New 
Hampshire died from overdoses last year. And nearly 500 the 
year before that. And companies like Janssen and Purdue Pharma 
fueled this epidemic, employing deceptive and truly 
unconscionable marketing tactics despite the known risks so you 
could sell more drugs to maximize your profits.
    And now you are refusing to take responsibility for your 
company's role in this crisis. So one more time, do you truly 
think that Janssen's opioid marketing practices were 
appropriate and responsible, or will you finally take 
responsibility for your company's role in helping create this 
crisis that is killing more than 100 Americans every day?
    Ms. Taubert. Everything that I have seen leads me to 
conclusively believe that everything that we have done with our 
products, when we promoted opioid products, which we stopped 
marketing a long time ago, was very appropriate and 
responsible.
    However, that being said, we do believe that we have a 
leadership position to take in helping with this. And so we are 
doing a number of things in terms of mothers and babies, and 
physician and patient education to help----
    Senator Hassan. So let me--again----
    [Simultaneous speech.]
    Ms. Taubert. We recognize we all play a part in trying to 
help this, because we realize that----
    Senator Hassan. Our time is done, but right now it is hard 
for me to take the industry's goal here as promoting good 
health seriously when its behavior to maximize sales of opioids 
created an epidemic.
    The Chairman. Senator Lankford?
    Senator Lankford. Thank you, Mr. Chairman.
    Thank you all for being here. And there are people alive in 
the United States, around the world right now, because of your 
companies and the work they have done with R&D along with the 
National Institutes of Health. And I fully acknowledge that, 
and I am grateful to the people who are researching and working 
right now, who are not watching this hearing because their face 
is in a microscope actually going through things to be able to 
research today and what they are doing.
    With that said--it is all of us who acknowledge that. We 
are trying to figure out the issue on drug pricing, because 
people in my State, whether they are on insulin or whether on 
Parkinson's drugs, or whether my own family or other people in 
my neighborhood, it is a very significant issue for them to try 
to figure out how to be able to manage this. So we have to get 
to the bottom of how we manage this.
    All of you have mentioned that the rebate issue has been a 
problem and that insurance companies and PBMs are very 
effective negotiators. Part of the challenge of this is, health 
insurance companies pay their PBM based on the quality of their 
negotiation skills, cutting a price off the list price. And so, 
if a list price is higher and a rebate is higher, that also 
gives preference to them. So the difficulty is, as you raise 
list price and the rebate gets larger, the insurance company 
gives that preference, making it harder for biosimilars. Am I 
tracking this correctly?
    So the challenge that we have with this is, how do we 
figure out how to break this down? Because we have insurance 
companies, PBMs, your companies that are creating the list 
prices, and then the biosimilars trying to be able to get into 
this.
    So, Mr. Frazier, you mentioned this, in particular about 
biosimilars and the difficulty of trying to be able to break 
into the market. Would you identify why it is hard for 
biosimilars to get into the market, which are inherently less 
expensive?
    Mr. Frazier. I would make two suggestions very quickly, 
because I know you only have a little bit of time here. One is, 
I think we have to educate physicians and other health-care 
providers about the value of biosimilars. I think, secondly, it 
would be very helpful if we could relieve patients of their 
obligation to pay copays for the cheaper biosimilars.
    Those would be two specific recommendations that I would 
make.
    Senator Lankford. Thank you. I appreciate that. For the 
Part B drugs, those physicians are paid a percentage of the 
drug costs. So a biosimilar, when it comes into the market in 
the Part B world, is, on its own, less attractive to a 
physician because a physician gets a higher percentage amount 
prescribing the more expensive drug, which then feeds down to 
the patient and the taxpayers, right?
    Mr. Frazier. That is correct.
    Senator Lankford. How do we break that chain?
    Mr. Frazier. I think that we--there are many ways that we 
would have to look at it. I do not have a specific suggestion 
here.
    I do think educating physicians is important here, and I 
think relieving patients, but we also have to look at the 
incentives.
    Dr. Bourla. Maybe I can----
    Senator Lankford. Dr. Bourla, please jump in, because you 
had mentioned this in your testimony as well.
    Dr. Bourla. I did, Senator, and thank you for giving me the 
opportunity.
    Let me give you a statistic that I think will present the 
magnitude of the problem. Here in the U.S., the penetration of 
biosimilars is much lower than in other places, but it is 
disproportional to different parts of the U.S. health-care 
system.
    For example, in open systems, systems where the decision-
maker is a PBM, one biosimilar or two has a market of 5 percent 
in the U.S. In closed systems, in systems like Kaiser, for 
example, with their integrated health-care systems--where the 
one who decides has the whole cost of the health-care system in 
its interest--we have 73 percent. Five percent versus 73 
percent for the same product.
    I agree with what Mr. Frazier said, that we need to create 
incentives, but I would add also that we need to break this 
rebate trap that creates significant disincentives for 
providers, and the health-care system, and insurance companies.
    Senator Lankford. Does anybody else want to jump in on 
that?
    Dr. Brandicourt. I can give you an example, Senator.
    The insulin market has a reputation of not being very 
competitive. In fact, it is, and we have biosimilars which have 
reached the market and have grabbed a very significant market 
share.
    We believe that when insulin will not be treated as a drug, 
but will be considered a biologic and can be submitted to 
biosimilar regulation in 2020, the biosimilar market share and 
penetration will be even higher.
    Senator Lankford. Thank you.
    My State, in particular, is working very hard on our 
Medicaid side, working on value-based pricing. I know that is 
something that several of you have mentioned before. It is the 
grand challenge of not pricing a drug based on the fact that it 
would be more expensive to do surgery and so we want to be 
slightly under the cost of surgery.
    We do have to be able to break through that model. Of 
course surgery would be more expensive than most of our 
treatments, but I think there is a benefit that we continue to 
experiment with if the drug is effective and we have a reducing 
price on it. And we can get a chance to be able to work through 
that, as we have done in our State.
    Mr. Frazier. We would support that.
    Senator Lankford. Well, we will continue to be able to work 
through other creative mechanisms. At the end, we cannot just 
have the taxpayer pay more and the consumer pay less, because 
that is really the consumer still paying. It just moves it to 
another spot.
    Mr. Chairman, thank you.
    The Chairman. Senator Cassidy?
    Senator Cassidy. First, think of innovation. As a doctor, I 
have seen cures for hepatitis C and therapies to control HIV, 
other inflammatory conditions, cancers that 30 years ago, when 
I graduated from medical school, were either death sentences or 
were a ticket to a lifetime of morbidity and complications. So 
I thank you for that. But I also say that some of my patients 
could not afford the medicine. And for them, it is as if the 
innovation never took place. And that is one concern.
    Secondly, another concern is, I think in some cases we do 
not have value. Now, Ms. Taubert, you suggested that PBMs are 
very effective negotiators. One drug that I want to bring up is 
Duexis, which is a combination of over-the-counter generic 
ibuprofen and Pepcid. Now, if I were to take this--and this is 
not the cheapest I could find it--in the doses that are used 
for Duexis, it would cost me 200 bucks a month. But it lists at 
over $2,400 to $2,600 a month.
    Now, that does not seem like very good negotiations on 
behalf of the PBM. And if the taxpayer is paying that money for 
something which over the counter is 200 bucks a month, and we 
are paying $2,600 a month, it is almost as if the taxpayer has 
``stupid'' written on their face, which they should not. That 
is unfair.
    This is not your medicine, but I use it to make the point 
that, right now, Medicare has a very limited ability to 
negotiate based on marginal value. And I think that is one of 
the fundamental problems in this.
    So that said, all things considered, since Medicare does 
have this very low ability, Ms. Taubert, do you think that 
Medicare should have the ability--if the PBM's negotiation does 
not work--should Medicare have the ability to negotiate based 
on value?
    Ms. Taubert. So we are very supportive of the notion of 
value-based contracting and results and----
    Senator Cassidy. This is a little bit different though, 
because we have been describing, on value-based contracting, is 
the cancer cured or not, is the hepatitis C cured or not? This 
is, my gosh, you are taking two generic medicines and charging 
ten times what they would cost over the counter.
    Ms. Taubert. Yes, and I agree that that example does not 
make any sense.
    Senator Cassidy. So is it reasonable then to ask that 
Medicare would have the ability to make some sort of judgment 
based upon relative value of a therapy?
    Ms. Taubert. I think, as we have talked about, if the PBMs 
are very effective in negotiating, we do not know that the 
government would be as effective in negotiating as the 
professional negotiators.
    Senator Cassidy. We do not know. I agree with that, but on 
the other hand it does--I have limited time. I do not mean to 
be rude. I do apologize. But there is this kind of shining 
example of where the PBM is not an effective negotiator. Yes, 
sir, Mr. Frazier?
    Mr. Frazier. I think this is where Chairman Grassley's 
opening statements about transparency come in. I think one of 
the keys of transparency is, it empowers patients and it 
empowers other payers to actually make informed choices about 
which of those two medicines makes sense.
    Senator Cassidy. Now, let me ask, because someone brought 
up the fact that Humira is now sold at an 80-percent discount 
in Denmark. And there is a Bernstein analysis which states that 
AbbVie still makes a profit because marginal cost in 
manufacturing is only about 5 percent of the manufacturing.
    So would this same entity have the ability to look not just 
at value, but at comparable drugs and at that which would bring 
value, because clearly biosimilars have had a much greater 
penetration in Europe, and the United States continues to pay 
top dollar for the same class of drugs. Something is 
fundamentally broken in our system when the Danes get an 80-
percent discount and we do not.
    Yes, sir?
    Mr. Frazier. I think we have to look at the way in which 
generic penetration happens outside the biosimilars market. 
When a drug goes off-patent----
    Senator Cassidy. Well, hang on, Mr. Frazier. I am sorry. I 
just get limited time, and I am going to hold you on that. 
Okay, I do not mean to--one of the things I have heard is that, 
if there is some limit on that profit, it may have a negative 
impact upon R&D. I think that has been a message here.
    But, Dr. Brandicourt, France has a committee on 
transparency which evaluates the relative added clinical 
benefit of a new drug. Price is then negotiated based upon that 
added benefit as well as other drugs in the market.
    Is it safe to say that your company has found that it still 
pays to innovate and to do R&D in France and to offer them 
access to the best cutting-edge drugs?
    Dr. Brandicourt. As a global company, we do have R&D in 
France. However, I would not use the French system as the 
benchmark of a good system.
    Senator Cassidy. But they do have access to these--I have 
limited time. I am sorry. They do have access to these drugs?
    Dr. Brandicourt. Well, that is a very good point. Some 
drugs are not put on the market because you do not get to the 
right pricing and therefore the right----
    Senator Cassidy. But if I am--I will finish with this. I do 
not mean to be rude. I apologize.
    In the international pricing index, we may quibble about 
the details, but if the U.S. would be paying 1.3 times a market 
basket of developed countries--a Germany, a France, a Canada, 
not smaller countries--we would still be paying more than they, 
but it would still have some relationship to reasonableness. 
And right now, it seems as if Medicare--in the absence of the 
ability to judge value--is almost a price taker when it should 
not be, as the largest purchaser.
    Dr. Brandicourt. You would ask countries where there is no 
negotiation, where prices are imposed, to set up your U.S. 
pricing. And I do not think that would be good policy.
    Senator Cassidy. It is imposed now, but it is imposed from 
the other side.
    The Chairman. Of the people who are still here, Bennet 
would be next, and then Whitehouse, and then Cortez Masto.
    Go ahead, Senator Bennet.
    Senator Bennet. Thank you, Mr. Chairman. Thank you so much 
for holding this hearing.
    There is not a town hall in Colorado where I do not hear 
how expensive drugs are forcing people to choose between life-
saving treatments or food and utilities. In our last hearing 
here, we heard from a mother whose son ate once a day in order 
to ration his insulin, because the full cost of the monthly 
treatment was $1,700. I do not think anybody here understands 
how that could be the case, but it is the case.
    And there has been a lot said here today about the 
important research and development that is going on in this 
country. And I, for one--and I know others share this view--
want to keep that in the United States. Having said that, I am 
trying to understand how Federal spending goes into 
prescription drug development, distribution, treatment, and 
pricing and yet Americans cannot afford their medications.
    The estimates of annual spending on prescription drugs 
range from $320 to $480 billion a year. The fact that we cannot 
even get a more precise number than that tells you something 
right off the bat, but those numbers include almost $100 
billion in Medicare Part D spending never paid for. Of that, 
$25 billion is in Medicare Part B. Medicaid spends almost $60 
billion on prescription drugs. This is what the taxpayer spends 
every year on prescription drugs.
    DoD and VA spending is about $11 billion. That number alone 
dwarfs the R&D budgets of some of your companies. Over 6 
years--slightly different point--but over 6 years between 2010 
and 2016, more than $100 billion was spent in NIH funding 
toward research that contributed to drug patents. Between $1 
and $2 billion is claimed annually through the orphan tax 
credit for drugs that treat rare diseases. Another $1 billion 
is annually claimed through the research and development tax 
credit. About $12 billion dollars is claimed annually through 
the direct-to-consumer advertising tax credit.
    I would ask you guys if I missed anything, but I think that 
is a pretty complete list of what we have. Yet notwithstanding 
that almost $500 billion, half a trillion dollars--by the way 
Medicare, you know, to spend all that money in Medicare, we are 
spending $2 for every dollar we are collecting. That delta is 
largely because of drug prices in the unfunded part of Medicare 
Part D.
    And here is what Coloradans have recently reported. In a 
recent survey on high drug prices, 22 percent did not fill a 
prescription, and 20 percent reported cutting pills in half or 
skipping doses. 
Seventy-four percent believe drug companies are charging too 
much money, and 91 percent believe the government should 
authorize the Attorney General to take legal action to prevent 
price gouging or unfair prescription drug price hikes--over 90 
percent.
    And that does not necessarily give you their legal 
judgment, but that is how keenly they are feeling the problem. 
And 90 percent believe the government should require drug 
companies to provide advance notice of price increases and 
information to justify those increases.
    So, I would ask all of you, or anybody who would care to 
answer, this question: how do we explain to our constituents on 
the one hand that we have this massive outlay of Federal funds, 
it is their taxpayer funds, and the on the other hand, the 
drugs they are buying are not affordable?
    And I realize there are all kinds of layers to this. I 
accept that. You know, there are the higher co-pays that you 
guys mentioned earlier from the insurance companies. That is a 
huge issue too.
    But I think that in a world where opacity or opaqueness has 
been, from the public's point of view, a business model for 
everybody in health care, whether it is the Federal Government 
or drug companies or insurance companies or doctors, nobody 
knows what anything actually costs. Nobody knows what anything 
will pay.
    My question, I guess, is, how do we better align the 
incentives here so that that huge outlay of money every year 
comes with affordable drugs at the end of the process?
    Mr. Gonzalez, thank you.
    Mr. Gonzalez. Senator, I can just tell you there is 
probably not anybody at this table who does not agree not a 
single American should go without drugs that they need. And I 
can tell you, that is the case at AbbVie.
    We do a lot of things to try to provide drugs for patients 
who cannot afford them. But there are certain patients whom we 
are unable to do that for based on the laws and the 
regulations, and in particular, most of Medicare Part D falls 
into that situation.
    And so I believe fundamentally we have to do two things. 
There are substantial discounts or rebates that are going into 
this system. Take Humira as an example. In the United States, 
there are rebates or discounts on that product that range from 
87 percent down to 26 percent. Okay, and it is the Federal 
Government that gets the highest form of discount or rebate on 
Humira, even though it represents a relatively small percentage 
of the volume, less than 20 percent of the overall volume.
    Now that does not mean that we could not do more. But what 
we are asking is, we do believe that there is a situation now 
where the co-pays for patients are such that it is extremely 
difficult for them to afford it. And what we are asking for 
is--``we,'' meaning AbbVie and I am sure others here, would 
like to do more. There is more we can do to help patients 
afford their medicines, but we have to eliminate some barriers 
that are blocking that.
    Today we give away to 81,000 patients free drugs; half of 
those are Humira. Of those Humira patients, half of them are 
Medicare Part D. They are patients who make less than 500 
percent of poverty, so they make less than $128,000 per year 
for a family of four.
    Those patients we can provide free drug for. Anybody above 
that, we cannot. It is considered an inducement.
    And when you look at the copay for a drug like Humira, 
commercial patients, Medicaid patients, the low-income subsidy 
patients in Medicare, pay less than $100 per year of copay for 
Humira. A standard Part D patient pays $5,500. They make 
$26,000, so they cannot afford it.
    Senator Bennet. I apologize. I know I am out of time. Thank 
you.
    The Chairman. Senator Whitehouse?
    Senator Bennet. Could I, Sheldon, just make one point, 
which is, I think what we ought to be doing is figuring out how 
people do not have to cut their prescription drugs in half, and 
that would be a worthy goal for this committee and the people 
on this panel.
    The Chairman. Senator Whitehouse?
    Senator Whitehouse. I would like to ask about a particular 
segment of the pharmaceutical market. Chairman Grassley opened 
his remarks by talking about patients taking a drug that has no 
competition as being a cause for concern.
    Mr. Frazier, your testimony included the statement that 
price gouging by those who jack up the prices of off-patent 
drugs that have no competition is a problem. Let me ask if 
there is anyone on this panel who disagrees, who disagrees that 
there are de facto off-patent monopolies now in the 
pharmaceutical market? Does anybody disagree with that as a 
fact?
    Mr. Frazier. I do not disagree.
    Senator Whitehouse. In fact it is true.
    Mr. Frazier. There are.
    Senator Whitehouse. There are.
    Mr. Frazier. That is what I was saying.
    Senator Whitehouse. And indeed, is it also not true that 
sometimes these off-patent monopolies are used to impose 
monopoly pricing?
    Mr. Frazier. It is true, and I think the most egregious 
examples that we have seen recently have been exactly in that 
situation.
    Senator Whitehouse. Does anybody disagree with that? 
Everybody agrees.
    Now are there, among those entities that are in that 
category with off-patent monopolies that are extracting 
monopoly pricing by virtue of that, entrants who are not even 
really in the pharmaceutical industry?
    Mr. Frazier. Absolutely there are.
    Senator Whitehouse. They invest nothing in R&D.
    Mr. Frazier. Exactly.
    Senator Whitehouse. They do not even come from the 
pharmaceutical industry.
    Mr. Frazier. Yes.
    Senator Whitehouse. They are more or less corporate raiders 
who have bought something in order to jack up prices and take 
advantage of monopoly rents. Correct?
    Mr. Frazier. There are many people like that.
    Senator Whitehouse. There are many people like that. Does 
anybody disagree that that is a feature right now within the 
pharmaceutical market? Everybody agrees?
    Dr. Bourla. And I would add also, Senator, that they are 
not allowed to be part of the Pharma Association.
    Senator Whitehouse. So here is the problem: it is not 
difficult, in my view as a lawyer of many years and a 
prosecutor of many years, to prove the existence of a monopoly. 
We have been proving the existence of de facto monopolies in 
courtrooms and in regulatory proceedings for decades.
    So we can identify where these monopolies exist, even if 
you let all the ties go to the runner so that, wherever there 
is a real question, you throw that one out. There still would 
remain a significant population of entities where it is beyond 
dispute that they are pricing based on monopoly power. And as I 
look around, there is no place to address that. There is no 
organization in the Federal Government that is taking an 
interest in that, and it is the scandal, I view, of the 
pharmaceutical industry. And you guys take a hit for it.
    Here is the problem: when we try to do anything about that, 
the people you pay to lobby us here in Congress come out and 
say, ``Nope, we cannot do anything like that. That might look 
like price control.'' We are not interested in taking any look 
at this monopoly problem in your industry. I should not even 
say it is in your industry, because I think a lot of these 
people are raiders into your industry who are not really part 
of your industry. They do not really develop drugs.
    I see a lot of head-nodding here. So help us solve at least 
that problem. You know, there are lots of other problems that 
we are going to have to look through with your pricing. Help us 
solve at least that problem. Turn off your lawyers and your 
lobbyists as antagonists when we try to solve that problem.
    Mr. Frazier. We will. Senator----
    Senator Whitehouse. In fact, switch them on and say, let us 
figure out how we deal with these modern monopolists who are 
not even really in the pharmaceutical industry.
    Mr. Frazier. I could not agree more. These people are at 
best tone-deaf, at worse abusive.
    I would also point out that there are companies here--I 
know, for example, my company. There is a very important cancer 
drug called TICE BCG. It was an invention of Merck. It has been 
off-patent for many many years. It is an incredibly essential 
drug for bladder cancer patients.
    A number of companies that were making it went out of the 
business. And so now we have had to double supply. Over the 
last nearly 12 years the cost of that drug has increased by 
$16. That is not how we make money at Merck. We make money at 
Merck by inventing new drugs that did not exist before.
    It is those people, I think, that contributed to the 
villainizing of an industry. The public cannot distinguish 
those people from the research-based companies.
    Senator Whitehouse. You all say that here. There is a lot 
of head-nodding here. There is a lot of agreement here.
    When your lobbyists come, everybody is in and they are not 
going to let anybody lose in all of this. We have to at least 
cut off these people.
    Mr. Frazier. Thank you for telling me that, because I never 
knew that our lobbyists were opposed to that.
    Senator Whitehouse. We have no support for working against 
these monopoly raiders.
    Dr. Brandicourt. Well, Senators, the message is very clear. 
And we are going to take that very seriously as a task.
    The Chairman. Senator Brown came back. So you will go ahead 
of the Senator from Nevada.
    Go ahead.
    Senator Brown. Thank you, Mr. Chairman. Thank you for doing 
this hearing.
    Thank you all for joining us. I want to thank Senator 
Hassan for her questions on opioids. Eleven people a day die in 
my State from opioid addiction, and there is a responsibility 
shared more widely than we sometimes say.
    I so appreciated Chairman Grassley's ``yes'' or ``no'' 
questions, and I appreciated the seven of you going along with 
his ``yes'' or ``no.'' And I would like to ask a series of 
``yes'' or ``no'' questions, and please keep it to ``yes'' or 
``no.'' They really are ``yes'' or ``no'' questions.
    Mr. Gonzales, let's start with you. Is it true that the 
pharmaceutical industry benefits from U.S. taxpayer-funded 
research? ``Yes'' or ``no''?
    Mr. Gonzalez. It is, yes.
    Senator Brown. Across, each of you.
    Mr. Soriot. Yes.
    Dr. Caforio. Yes.
    Ms. Taubert. Yes.
    Mr. Frazier. Yes.
    Dr. Bourla. Yes.
    Dr. Brandicourt. Yes.
    Senator Brown. Okay. Thank you.
    Is it true that no other nation invests more taxpayer 
dollars in basic research that directly and indirectly benefits 
the industry?
    Mr. Gonzalez. Yes.
    Mr. Soriot. Yes.
    Dr. Caforio. Yes.
    Ms. Taubert. Yes.
    Mr. Frazier. Yes.
    Dr. Bourla. I am not sure I understood the question.
    Senator Brown. Is it true that no other nation on earth 
invests more taxpayer dollars in basic research?
    Dr. Bourla. Yes.
    Dr. Brandicourt. Is it proportional to GDP, Senator?
    Senator Brown. I am not asking that, but that is close 
enough. Thank you.
    Is it true that the U.S. Government allows drug companies 
the longest period of exclusivity on biologics?
    Mr. Gonzalez?
    Mr. Gonzalez. I believe that is true.
    Mr. Soriot. I believe that is true.
    Dr. Caforio. I believe that is true.
    Ms. Taubert. Yes.
    Mr. Frazier. Yes.
    Dr. Bourla. Yes.
    Dr. Brandicourt. Yes.
    Senator Brown. We know Medicare limits prices with doctors 
and hospitals. Is it true that Medicare cannot negotiate to 
lower prices with drug companies?
    Mr. Gonzalez. That is true directly.
    Mr. Soriot. Yes.
    Dr. Caforio. Yes.
    Ms. Taubert. Yes; other agents work on their behalf to 
negotiate, but they do not negotiate directly.
    Mr. Frazier. Yes, they cannot negotiate directly.
    Dr. Bourla. Yes.
    Dr. Brandicourt. Yes.
    Senator Brown. Thank you.
    Is it true U.S. taxpayers subsidize pharmaceutical 
advertising and marketing activities through the tax code's 
business expense deduction?
    Mr. Gonzalez?
    Mr. Gonzalez. Yes.
    Mr. Soriot. Yes.
    Dr. Caforio. Yes.
    Ms. Taubert. Yes.
    Mr. Frazier. Yes, no different from any other advertising, 
but yes.
    Dr. Bourla. Yes.
    Dr. Brandicourt. Yes.
    Senator Brown. Thank you.
    We note the United States is the world's largest market for 
pharmaceuticals. Is it true that we pay the highest--in the 
overwhelming number of cases, is it true that we pay the 
highest drug prices in the world?
    Mr. Gonzalez?
    Mr. Gonzalez. The average government price would--that 
would not be the case.
    Senator Brown. No, that we as Americans individually pay 
the highest drug prices in the world?
    Mr. Gonzalez. As an average, that would be true.
    Mr. Soriot. I am not sure that it would be true, Senator, 
because the generic prices are some of the lowest in the world, 
and government prices, for many of our drugs even before patent 
expiry, are sometimes as low as Europe or lower.
    So on average, probably it is true, but there are many many 
different kinds of----
    Senator Brown. I know there are exceptions. I am looking 
for an average.
    Dr. Caforio?
    Dr. Caforio. Yes, on average I would say.
    Senator Brown. Ms. Taubert?
    Ms. Taubert. I would say that the list prices are higher, 
but the net price in the United States is more comparable to 
much of the pricing outside the U.S.
    Senator Brown. Mr. Frazier?
    Mr. Frazier. Yes, outside Medicaid and other things, yes.
    Senator Brown. Okay.
    Dr. Bourla. Nine out of 10 products in the U.S. are 
generics. So the pricing of the generic products is much lower 
in the U.S. than other countries.
    Senator Brown. Yes, but generics----
    Dr. Bourla. But you are right about branded----
    Senator Brown. Do not confuse generic numbers of drugs sold 
with cost in the aggregate? Your answer?
    Dr. Bourla. But nine out of 10, I am telling you--you are 
right that in the innovation, the prices outside the U.S. in 
many cases are much higher.
    Dr. Brandicourt. So I would agree with that: patented 
drugs, yes, generics, no.
    Senator Brown. Okay. Thank you. Last question.
    Is it true that drug manufacturers set the--what Ms. 
Taubert talked about--list prices? Is it true that you, the 
drug manufacturers, set those list prices?
    Mr. Gonzalez. That is correct.
    Mr. Soriot. That is correct, but of course, there is a 
negotiation that takes place with PBMs and insurers about the 
price and the rebate level.
    Senator Brown. Dr. Caforio?
    Dr. Caforio. It is true for list price, but the delta 
between list and net price is the highest in the U.S.
    Senator Brown. Ms. Taubert?
    Ms. Taubert. Correct. Yes, we set the list price.
    Senator Brown. Mr. Frazier?
    Mr. Frazier. Yes, we set list price.
    Senator Brown. Dr. Bourla?
    Dr. Bourla. Actually, I would not agree that we set the 
list price. It is the result of a major negotiation. And I have 
to say that the problem in the U.S. health-care system it is 
that everything is geared around list price, a lot of 
incentives, which creates a hydraulic effect for the list 
prices to go down.
    I would be very happy to have much less list prices and the 
same net.
    Senator Brown. Dr. Brandicourt?
    Dr. Brandicourt. Ultimately, we set the listing price.
    Senator Brown. Okay. Thank you.
    So taxpayers subsidize your research, subsidize your 
marketing, and you continue to raise drug list prices on them. 
The median income of a person on Medicare is $26,000 a year, 
while the average annual cost for a single specialty medication 
was more than $52,000 in 2015. Americans cannot afford to pay 
for prescription drugs that cost more money than they make in a 
year. We cannot continue to give big pharma the blank check 
that you have had to pay for high-priced prescription drugs.
    But I guess it is not surprising that big drug companies 
take all the taxpayer money they can. What is so troubling is 
that this Congress continues, because of the lobbyists that 
Senator Whitehouse talked about and other pressures, that this 
Congress continues to allow you to do so.
    Thank you for answers.
    The Chairman. The Senator from Nevada.
    Senator Cortez Masto. Thank you for being here. Thank you, 
Mr. Chairman and Ranking Member, for this important hearing, 
one of four.
    Let me follow up on Senator Brown's line of questioning. Do 
any of you invest more in R&D than you spend on marketing and 
administration? If we could start ``yes'' or ``no'' to the 
right here.
    Dr. Brandicourt. No.
    Dr. Bourla. No.
    Mr. Frazier. Spend more on R&D versus marketing?
    Senator Cortez Masto. More in R&D than you spend on 
marketing and administration. Do you invest more in R&D than 
you do on marketing?
    Mr. Frazier. On marketing, but not if you include general 
administration, facilities, and all of that stuff. But yes, 
more than marketing.
    Senator Cortez Masto. Okay.
    Dr. Bourla. I would correct my answer also if it is only 
marketing. Yes, we spend more on R&D.
    Senator Cortez Masto. Let us just do marketing.
    Dr. Brandicourt [indicating agreement with Dr. Bourla].
    Ms. Taubert. Yes, we spend 86 percent more on R&D than we 
do on sales and marketing.
    Senator Cortez Masto. Okay.
    Dr. Caforio. Yes, we do more on R&D.
    Mr. Soriot. Same, more than marketing, but excluding 
administrative costs.
    Mr. Gonzalez. Significantly more in R&D than sales and 
marketing.
    Senator Cortez Masto. But if you included administration 
with the marketing, that would be the reverse. Is that correct?
    Mr. Gonzalez. That is correct.
    Senator Cortez Masto. Yes from the rest of you?
    Mr. Frazier. It is about tied at Merck.
    Senator Cortez Masto. Okay.
    So let me just ask this question. Apart from New Zealand, 
nowhere else in the world will you see drug ads on television--
and I have asked this question for some of you. My 
understanding is--the answer that I have been given is that you 
maintain that television ads are a critical public health tool 
that helps patients identify their symptoms and seek treatment.
    Would you all agree with that? Is that a ``yes''? ``No''? 
Why do we have television ads when it----
    Dr. Brandicourt. Yes, you are right.
    Senator Cortez Masto. Is that why? Is that a ``yes''?
    Dr. Brandicourt. Yes.
    Dr. Bourla. Yes.
    Mr. Frazier. Yes.
    Ms. Taubert. Yes.
    Dr. Caforio. Yes.
    Mr. Soriot. Yes.
    Mr. Gonzalez. Yes.
    Senator Cortez Masto. Okay. So if you maintain that 
television ads are a critical public health tool, then how can 
that be if our health outcomes are not significantly better 
than in those countries where it is outlawed?
    Dr. Bourla. Thank you, and you are raising a very good 
point.
    I think that the health-care outcomes and life expectancy--
there are a lot of factors that influence them. For example, 
exercise, diet, lifestyle, and I feel that our Nation needs to 
improve a lot in many of these cases. But I can assure you, 
Senator, that if you get cancer or another serious disease, you 
want to be treated in this country.
    Senator Cortez Masto. Okay.
    Dr. Bourla. There is no comparison.
    Senator Cortez Masto. All right. So let me jump back then 
to this discussion on authorized generics. And I am trying to 
understand this, I think, along with all of my colleagues, to 
address how we reduce the cost and get the drugs in the hands 
of the people who need them--where the R&D came in, where they 
were created--for individuals who actually need the drugs.
    I want to ask about the concept of authorized generics. 
Those, as you know, are the drugs that are identical to the 
brand, manufactured by the brand, but marketed without the 
brand on its label.
    Yet the companies, my understanding is, keep selling the 
higher-cost brand drug to consumers who, according to press 
reports, do not realize that the same product from the same 
company is available at a better price.
    All of you manufacture authorized generics to maintain your 
market share once your patent expires. Is that true?
    Dr. Brandicourt. No.
    Senator Cortez Masto. That is not true?
    Dr. Bourla. We do have authorized generics.
    Dr. Brandicourt. We do have authorized generics, but do not 
do it with the goal that you just highlighted.
    Senator Cortez Masto. So you do have authorized generics? 
Do all of you have authorized generics?
    Mr. Frazier. For some brands.
    Senator Cortez Masto. Okay.
    Ms. Taubert. Very selectively.
    Dr. Caforio. Very selectively.
    Mr. Soriot. We do not.
    Senator Cortez Masto. You do not?
    Mr. Gonzalez. I do not believe we do.
    Senator Cortez Masto. You do not have authorized generics? 
So for those of you who have authorized generics, explain to 
me, if you do have those, why do you continue selling the 
brand?
    Mr. Frazier. Okay, so in our case when we have had 
authorized generics, we have allowed a third-party to bring a 
generic product to market. The issue that you are really 
getting to, again, is the issue that Senator Cassidy talked 
about, which is transparency.
    At the end of the day, if patients really understood what 
their options were, they would not make these choices. But we 
have an opaque system, which is something that I think we have 
to change. We have to empower patients to be able to choose the 
cheapest medication. And Merck strongly supports generics.
    What I said in my introduction is, we will never use 
coupons when there is a generic.
    Senator Cortez Masto. What are you doing to empower the 
patients? What are you doing to empower the patients to 
understand that the generics are out there?
    Mr. Frazier. It is very hard. We do not connect with the 
patients in all those situations. That is why there is 
legislation saying, for example, that pharmacists must tell 
patients at the counter what the cheapest alternative is for 
them at the counter. We do not----
    Senator Cortez Masto. So you rely on others to tell----
    Mr. Frazier. Yes. We do not meet them at the counter, 
Senator.
    Senator Cortez Masto. Okay. Let me ask one final question, 
because I am running out of time here. I want to get a sense 
from all of you what types of policies you could support. I 
have heard some of those, but let me ask you this. Democrats 
have proposed to require manufacturers to submit advanced 
justification for price hikes that outpace inflation and make 
that information public.
    Given that many of you have already committed to tapering 
price hikes, is this something you could support, ``yes'' or 
``no''?
    Dr. Brandicourt. We can support such legislation, yes.
    Dr. Bourla. Yes.
    Senator Cortez Masto. Thank you.
    Dr. Caforio. Yes.
    Ms. Taubert. We are very supportive of increased pricing 
transparency. Advance notification can cause problems in the 
supply chain and could cause outages for certain States. So we 
are very supportive of the notion of transparency. Advance 
notification can be problematic.
    Senator Cortez Masto. Okay.
    Dr. Caforio. We disclose our price increases.
    Senator Cortez Masto. Okay.
    Mr. Soriot. We support it.
    Mr. Gonzalez. We support it, but we would like to see 
consistency. As you probably know, California has that right 
now, but if we had a consistent standard that we operated with, 
that would certainly be helpful.
    Senator Cortez Masto. Thank you. Thank you very much.
    The Chairman. Senator Daines?
    Senator Daines. It is very clear from what is going on 
today that there are ultimately not any silver bullets to cure 
the high cost of prescription drugs. I am pleased that we can 
have this discussion. My hope is that we can truly find some 
ways to incentivize the system here to deliver a lower price, 
ultimately, for the consumer as well as incentivizing 
innovation.
    As manufacturers, you are responsible for setting this list 
price, this ethereal list price. But the more I hear what is 
going on here today, I am convinced we probably should call 
this the asking price. I am sure ``list price'' is a bit of a 
misnomer, because after hearing all about coupons, rebates, 
discounts, the pricing volatility--yes, I spent 13 years at 
Procter and Gamble, and once upon a time we drove a business 
with a lot of coupons, with rebates, pricing incentives. It was 
a very elastic pricing model. Oftentimes, we had a high-margin 
business. There is elasticity in the pricing, and you are an 
example of that.
    I spent 12 years in the cloud computing business after 
that. The margins were even higher. We saw great volatility in 
pricing and elasticity in pricing. We eventually, years ago of 
course, went to the everyday low price, EDLP, model. It, again, 
may or may not apply to Pharma. But it was just trying to take 
out all of that in between the manufacturer and the consumer 
nonsense that was going on, that was lacking transparency.
    And ultimately, I think the consumer was not winning in 
that equation, because the prices--they were not seeing really 
the true everyday low price. There are a lot of perverse 
incentives in the system today, as best I can tell. So my 
question is, who pays list price?
    Dr. Brandicourt. Unfortunately, the patient at the end, at 
the pharmacy counter, is probably one of the few paying the 
list price.
    Mr. Frazier. There is a small percentage of people who have 
no insurance who could actually be charged the list price.
    Senator Daines. So the people who can afford it the least, 
arguably, are paying list price.
    Mr. Frazier. Senator, that to me is what I meant by saying, 
in some ways the reimbursement system here is regressive. The 
people who can least afford it are paying the most.
    Senator Daines. Do you think that that is a good system?
    Mr. Frazier. I do not. I can tell you that is, to me, the 
biggest problem that we have as a country, that we now have a 
system where the poorest and the sickest are subsidizing 
others.
    Senator Daines. Okay. So with insurance companies that now 
own the PBMs and the supply chain from the time you list the 
price until the consumer eventually gets it, is it fair to say 
the list price is really a starting point for, then, a 
negotiation?
    Mr. Frazier. Yes.
    Senator Daines. Does anybody disagree with that premise?
    Ms. Taubert. No.
    Senator Daines. So what are some of the incentives? And 
maybe we will start with Mr. Frazier. What are the incentives 
that contribute to high list prices that are being paid by 
those who can afford them least?
    Mr. Frazier. The real answer, Senator, is, if you went back 
a few years ago when we negotiated to get our drugs on 
formulary, our goal was to have the lowest copay for patients.
    Today the goal is to pay into the supply chain the biggest 
rebate. And so that actually puts the patient at a 
disadvantage, since they are the only ones who are paying a 
portion of the list price. The list price is actually working 
against the patient.
    Senator Daines. So why do we have a system today where you 
all are setting--I will just say very very high list prices, 
which is our starting point for negotiation? Why?
    Dr. Brandicourt. Senator, we are trying to get formulary 
position with those high list prices, high rebates. It is a 
preferred position. Unfortunately, the preferred position does 
not automatically ensure affordability at the end of the day.
    Mr. Frazier. And, Senator, if you bring a product to the 
market with a low list price in this system, you get punished 
financially and you get no uptake, because everyone in the 
supply chain makes money as a result of a higher list price.
    Senator Daines. Chairman Grassley, if I could just ask a 
follow-up question here. And that is, the GAO report said that 
generics might fall 20 percent for each new generic entrant 
into the market.
    I appreciate the chairman's efforts here with the CREATES 
Act. It is going to crack down on some of these bad actors who 
block or delay competing generic drugs from entering the 
market. I have co-sponsored the bill, and I think that will 
help us provide better access to low-cost generics.
    Here is my question: has your company ever withheld samples 
from generic manufacturers?
    Dr. Brandicourt. No.
    Dr. Bourla. No.
    Mr. Frazier. No.
    Ms. Taubert. No.
    Dr. Caforio. No.
    Mr. Soriot. No.
    Mr. Gonzalez. No.
    Senator Daines. Right. Do you believe the CREATES Act would 
be a positive step forward, ensuring generics enter the market 
in a timely fashion? I would love to poll the team here.
    Mr. Frazier. I said in my testimony, legislation like the 
CREATES Act would be positive in that regard.
    Dr. Bourla. Yes.
    Dr. Brandicourt. Yes.
    Dr. Caforio. Yes.
    Mr. Soriot. Yes.
    Mr. Gonzalez. We are supportive.
    Ms. Taubert. We are supportive of efforts to make sure that 
there are no abuses of that sample system.
    Senator Daines. All right; I am out a time now. Thank you.
    The Chairman. Senator Young?
    Senator Young. Thank you, Mr. Chairman.
    I want to move to the issue of Medicaid best price. In the 
Trump administration's blueprint, they suggest that because 
drug manufacturers have to give Medicaid the best price drugs, 
there is no incentive to offer deeper discounts to other 
payers, both government and commercial, than what is already 
offered under the Medicaid drug rebate program.
    So first of all, I would ask each of you, is the Trump 
administration's assessment accurate?
    Mr. Gonzalez. In concept, I would say I understand the 
concept. In other words, if you have best price, you obviously 
have to be conscious of where that price is going, because it 
is going to be compared against that.
    I would tell you in practice, because of the negotiation 
that occurs in the formula around Medicaid, I do not believe 
that that is actually, today, resulting in higher prices in the 
Medicare program.
    Senator Young. You have anticipated my follow-up question. 
So I appreciate that.
    So the best price requirement does not encourage 
manufacturers to increase initial prices? You have thoughts on 
that?
    Mr. Gonzalez. I would say it does not necessarily encourage 
you to set a higher list price. I think what happens with list 
price is this negotiation you have heard of, going forward, 
where you are looking for a certain amount of impact to fall 
through, but the rebates and the other aspects of the value 
chain in between absorb a large chunk of that, which drives 
list prices, increases up higher.
    Senator Young. Okay. Others?
    Mr. Frazier. I think where best price really is an issue 
is, again, it is a barrier to the kind of value-based pricing 
that we want to have within the marketplace, where if, for 
example, a drug did not work, you might reimburse that payer 
for that unit, where that becomes a problem for value-based 
pricing.
    Dr. Brandicourt. Another example, Senator, is when you want 
to put on the market a second NDC, like we did recently where 
it had a much lower list price, then the best price potentially 
becomes a problem because it is calculated with the other 
version, the higher list price version, which has stayed on the 
market. So that is something to pay attention to.
    Senator Young. What changes, if any--if I could pivot a 
bit--would you suggest making to the program?
    Dr. Caforio. Senator, I believe that flexibility with 
value-based arrangements is really important, because I think 
we have all expressed a strong support for a system where we 
are paid based on the clinical results that our medicines 
produce in patients and having greater flexibility to do that.
    It would be very, very important. It would be very valuable 
for patients. It would reduce health-care costs overall.
    Senator Young. General agreement?
    Ms. Taubert. Yes, we agree.
    Mr. Frazier. Yes.
    Senator Young. Okay.
    So would you be willing to work with the administration on 
a different model, one you regard as more optimal?
    Ms. Taubert. Absolutely.
    Senator Young. Very good. Thank you.
    With respect to reducing drug prices and the subsidies that 
U.S. payers provide with respect to research and development to 
much of the rest of the wealthy world, the President and the 
administration have gone so far as to issue proposals, like the 
international pricing index, which we all are familiar with, to 
bring down prescription drug prices.
    So with the increased scrutiny of the industry and of the 
drug supply chain as a whole in the U.S., have any of your 
companies re-evaluated your business strategy in foreign 
countries?
    Mr. Frazier. That is a common question that we get asked. 
And the answer to that question is, we do everything in our 
power to ensure that there is less freeloading by governments 
outside the United States. But the reality of the world is, the 
greatest opportunity we have is to walk away.
    And that is really challenging when you have the kinds of 
essential medicines that make a big difference to people's 
lives. And frankly, they know that. They know that they can 
establish a price, and that ultimately what we have is an 
option to walk away, leaving patients behind.
    I would also make the point that has been made several 
times here, that in the course of negotiating for 
reimbursement, often those countries take a very deliberate 
approach, such that these medicines are available many years 
later than they are here.
    So they not only negotiate on a low price, but they 
actually provide very few of these medicines early on to their 
populations. If you look at, for example, lung cancer, where in 
this country now, there is data showing that certain medicines 
can reduce the risk of death by 50 percent in newly diagnosed 
lung cancer patients, compare that to the UK, where people die 
regularly of lung cancer because they do not have these 
medicines.
    Mr. Soriot. Senator, I think it is important to keep in 
mind that all these investments, number one, create a lot of 
very good jobs in the U.S. and economic value that really 
benefits the country. And second, they allow patients to get 
access to important new medicines much, much, much earlier than 
in Europe, for instance, sometimes 3, 4 years before.
    And I share Mr. Frazier's comment here. I have many 
examples that I could share where medicines that save lives are 
available here. We are still waiting in Europe.
    The Chairman. Just three more questions. One from--if some 
of you want to answer yet, I did not mean to interrupt you. Go 
ahead.
    Mr. Gonzalez. The only thing I would add is, if we could 
develop a model where, as in the early days of HIV when 
countries ultimately shared the burden, knowing that you would 
have to provide HIV treatments at a very low cost in certain 
countries, there was a tiered pricing system that came through 
where, yes, the U.S. paid the highest price, but the Europeans 
paid a fairly significant price for very important specialty 
medicines. If we could negotiate through trade or other 
mechanisms, we would be able to get a more balanced sharing of 
the investment that is made, not keeping all of that burden on 
the U.S., because the U.S. does bear the bulk of the burden of 
innovation in our business. That is absolutely true.
    Senator Young. So that is a really interesting idea. If you 
or your team are aware of any academic paper you might bring to 
my attention----
    The Chairman. Okay. That is the end.
    Senator Young. Thank you, Mr. Chairman.
    The Chairman. Yes.
    Now we have three questions, one from Senator Wyden, then 
Senator Cassidy, then me. And then that will be it.
    Senator Wyden. Thank you very much, Mr. Chairman.
    This is going to be one question and then a very brief 
closer. And the question is for you, Mr. Gonzalez.
    I have the company's proxy statement here. And financial 
disclosures show that you were paid $22.6 million in 2017, and 
that included a $4.3-million bonus. That is what I want to look 
at.
    On page 37 in this proxy statement, it says your bonus was 
tied to the financial performance of Humira. And it seems that 
was the case in 2015 and 2016. That strikes me as problematic, 
since AbbVie reported that the higher prices in the U.S. were 
responsible for increasing sales of Humira.
    Would you make a smaller bonus if you dropped the price of 
Humira?
    Mr. Gonzalez. Humira was one element of a set of financial 
factors that were evaluated as part of my compensation. It is 
obviously a very significant product for us. So it is clear 
that it would be a part of that evaluation.
    Senator Wyden. I would like that in writing. It looks to me 
like you would be making a smaller bonus if you dropped the 
price of Humira. I would like that in writing within 10 days.
    My last point--Mr. Chairman, I appreciate being able to do 
this for a closer--is that I have heard a lot of happy talk 
this morning, things like, well, if you get rid of rebates, 
drug prices are going to go down. But what people are taking 
away from this hearing is--I have seen it said and reported--
well, no firm commitments have been made to lower list prices.
    So I am just going to tell you what I would like in writing 
is, I would like an answer in writing to the question, if 
rebates go away, will you support a black letter law that 
requires that you reduce list prices by the amount of the 
rebate?
    I am going to get that to you right away. I would like an 
answer within 10 days, because that is right at the heart of 
this issue, and after the ``happy talk'' is over, that is what 
is really going to help people at pharmacy counters from sea to 
shining sea.
    Thank you, Mr. Chairman.
    The Chairman. Senator Cassidy?
    Senator Cassidy. Thank you, Mr. Chairman.
    Thank you, again. This has been incredibly provocative. And 
if there is a tension here, the tension is, how do we support 
innovation, but at the same time make it that the patient can 
afford that innovation?
    Mr. Frazier, you may have guessed that--it seems like we 
have a mirror image, in my mind. Either the plans impose a 
price or the government imposes a price. But either way, the 
side having it imposed upon them is not very wild about that.
    And you just mentioned to Todd Young that you can walk 
away. If France offers you too low a price, you just walk away 
from France. The UK does not have a deal right now. But in some 
areas, Medicare cannot walk away. So it is back to that mirror 
image. And you started to say something and I was out of time. 
But my question is, in the six protected classes--and if there 
is a new drug, like Sovaldi was at the beginning, right now the 
commercials can walk away, the commercials can delay, but 
Medicare cannot.
    So help me resolve this. How do we give the patient, the 
taxpayer, the same sort of tools that--and by the way, CBO says 
unless you can walk away, negotiations will not lower prices.
    Mr. Frazier. So my point was, for all practical purposes, 
we cannot walk away from our European colleagues, even though 
they give us low prices, because we think it would be immoral 
to leave those patients----
    Senator Cassidy. Now some of your colleagues have, because 
there are drugs not yet available in the UK.
    Mr. Frazier. Well, the problem with the UK is that they 
delay. Just like they can set the price, they delay when they 
put the drug on the market. It is the UK's delay, it is not our 
delay. So I want to clarify that point.
    But coming back to your six protected classes, those 
protected classes are there because many, many sick vulnerable 
people need medicines in those classes. And we believe that 
there are ways of lowering the prices, stimulating innovation, 
without violating the compact that was around those six 
protected classes, because patients are particularly needing 
those medicines.
    Senator Cassidy. Well, we will have to leave it there, but 
I am not sure that is--you know, that seems almost status quo. 
And status quo is kind of not working.
    But again, thank you all very much, and I thank you again 
for your innovation.
    Dr. Bourla. I would add, Senator, I believe the 
administration should try, through trade agreements, to protect 
the American innovation, because by and large the 
pharmaceutical innovation is happening in this country. And 
right now, I think rightly, these price control mechanisms are 
for multiple well-developed countries. It is in reality free-
riding on American innovation.
    Senator Cassidy. Okay.
    Well, thank you.
    The Chairman. My last question is very general, but I would 
like to know if there are any policies affecting Medicaid or 
Medicare that are in your control to change? In other words, 
from the company level, is there anything in your control that 
you could change on Medicare or Medicaid?
    I will start with you on my right here.
    Dr. Brandicourt. I do not think we can change directly any 
policy, Senator, on Medicare or Medicaid. We can talk about 
different solutions, but I do not think we can change. We have 
no power to change.
    The Chairman. But if you lowered your list price, it would 
help. That is one thing you could do.
    Dr. Brandicourt. If we were able to lower our list price, 
that would certainly help, again, the patient at the end, at 
the pharmacy, to have a copay which they could afford.
    However, we could not do that independently of a major 
reform because we would lose formulary placement if we were 
doing that in isolation, and especially in very competitive 
areas where you do have, you know, brands and generics. And 
again, I am referring to the insulin market, which has become 
extremely, extremely competitive. That would not work.
    The Chairman. Do you have anything?
    Dr. Bourla. Mr. Chairman, I think the most impactful thing 
I can do right now it is to make the pledge that, as leader of 
this company, Pfizer, I would be taking very seriously the 
responsible pricing of our products. This is something that we 
have already started.
    Pricing at Pfizer in the past was growing in the mid-single 
digits, even more in some cases. This is not something that we 
continued doing. Pricing at Pfizer went down last year, went 
down this year.
    And when I spoke to our investors, not to the Senate, to 
our investors, I made it very clear that pricing will not be a 
growth driver for this company now or in the years to come. Why 
do I think this is the most important? Because I think the tone 
is set from the top.
    The Chairman. Mr. Frazier?
    Mr. Frazier. Senator, I understand the dissatisfaction with 
our industry. I understand why patients are frustrated, because 
they need these medicines and they cannot afford them.
    I would pledge to do everything that we could, but I would 
urge you to recognize that the system itself is complex, and it 
is interdependent. And no one company can unilaterally lower 
list prices without running into financial and operating 
disadvantages that make it impossible to do that. But if we 
bring all the parties together around the table with the goal 
of doing what is best for the patient, I think we can come up 
with a system that works for all Americans.
    Thank you for giving us the time today.
    The Chairman. I did not mean to--for the rest of you, 
before you answer, I did not mean to say list price. I just 
said, well, that is kind of obvious. Yes, I did not want to 
concentrate just on that.
    Ms. Taubert?
    Ms. Taubert. We really want to be a part of the solution, 
and we want patients to be able to access and pay for the 
medicines that they so desperately need. So we do strongly 
advocate for rebate reforms that would allow us to lower our 
list prices that would then end up helping patients get access.
    The Chairman. Dr. Caforio?
    Dr. Caforio. Mr. Chairman, I would echo. Our perspective is 
that it starts with a very responsible and thoughtful approach 
to pricing and price increases. That is what Bristol-Myers 
Squibb does.
    The second point that I would like to make is that, today 
we have discussed a number of very concrete policies, from 
addressing the issue of rebates to value-based pricing to 
supporting the development of a generic and biosimilar market. 
And you have my commitment that our company is looking forward 
to working with this committee and the administration to make 
sure that many of those policies can be enacted, because they 
would make a very big difference for our patients.
    The Chairman. Mr. Soriot?
    Mr. Soriot. Senator, we actually cannot influence policy. 
What we can do is, indeed, apply reasonable pricing and also 
continue pushing for value-based pricing. But I would like to 
make a general comment, which is that hopefully--you know, 
hopefully my colleagues will share this. This view is that I 
really do not think we are blaming anybody in the system. In 
his introduction, Senator Wyden thought that we were placing 
the blame on PBMs and others. I really do not think we are 
doing this.
    I think what it is is that we are in a system that used to 
be fit for purpose and really drove enormous savings over the 
last few years but is no longer fit for purpose. And it is one 
of those situations where nobody in the system can do anything, 
can fix it by themselves. The government has to step up and 
change the rules, and those rebates have to go.
    The Chairman. Mr. Gonzalez?
    Mr. Gonzalez. I think I would agree with many of the points 
that were already raised. We as an industry have to continue to 
do everything we can to be responsible about pricing in both 
how we set pricing and price increases over time. I think we 
have seen a positive trend in that area. But ultimately, the 
final fixes here to realign the system appropriately would 
require legislative-type changes.
    The only other thing I would say is, as I mentioned a 
moment ago, we are absolutely committed that no patient goes 
without medicine of ours that they need. And we have an 
extensive patient assistance program, but we are talking about 
how we more broadly ensure all patients understand they can get 
that support from us if they cannot afford their medicines.
    The Chairman. I want to inform all members of the committee 
that I will set a deadline of March 12th if you have questions 
you want to submit to the panel for answers in writing. And 
then for you folks, after you get those questions, I hope you 
can get back to us very quickly.
    And so, all of the people besides the witnesses who have 
attended either here or off-site for this hearing, I thank you 
for your interest in this issue. And I want to once again thank 
our witnesses for being here today and sharing your knowledge 
and expertise. And I indicated that this is the start of a 
dialogue I hope to have with you so that we can correct some of 
these things that have been pointed out at this committee 
meeting that we think need to be corrected.
    Thank you all very much.
    Meeting adjourned.
    [Whereupon, at 1:25 p.m., the hearing was concluded.]

                            A P P E N D I X

              Additional Material Submitted for the Record

                              ----------                              


           Prepared Statement of Albert Bourla, DVM, Ph.D., 
                    Chief Executive Officer, Pfizer
    Chairman Grassley, Ranking Member Wyden, and members of the 
committee, thank you for the opportunity to speak with you today. My 
name is Albert Bourla. I have been with Pfizer for 26 years, and just 
last month had the honor of becoming its chief executive officer.

    Today, I am pleased to take part in such an important policy 
discussion within the United States Senate. Pfizer shares an important 
goal with this committee: to ensure that America remains the leader 
when it comes to innovative medicines, and that our citizens have 
affordable access to these modern miracles when they need them.

    In that frightening moment when you hear that you or a loved one 
has been diagnosed with a serious disease, one question comes to mind: 
``Is there a cure or treatment available?'' The answer can change your 
life. And happily, the answer to that question increasingly is ``yes.''

    Breakthrough medicines are coming quickly across a wide range of 
conditions. Most of them are discovered here, by the American 
Biopharmaceutical Industry, which is the crown jewel of innovation. Let 
me share a few examples. In 2015, Pfizer launched a life-changing new 
treatment for metastatic breast cancer that can delay the progression 
of the disease two times longer than previous treatments. Thanks to our 
meningitis B vaccine, parents can send their teens to college confident 
in the knowledge that being vaccinated helps protect them in the event 
of an outbreak on campus. In 2018, we brought 4 new cancer treatments 
to the market to treat varying forms of breast cancer, lung cancer and 
leukemia. And we are currently working on a non-opioid alternative with 
the potential to address the serious unmet needs of the more than 27 
million Americans living with osteoarthritis and the more than 33 
million suffering chronic low back pain.

    But all of these breakthroughs won't do anyone any good if patients 
can't afford them.

    That's why at Pfizer we are so committed to our purpose: 
breakthroughs that change patients' lives. Pfizer's more than 90,000 
colleagues around the world come to work every day focused not only on 
creating breakthrough medicines, but also on making sure those 
medicines get into the hands of the patients who need them.

    To create solutions that make medicines affordable for patients and 
our entire health-care system, I believe that all players in the 
industry must come together and play a part. Whether it's hospitals or 
providers, pharmacy benefit managers or insurance companies, or 
biopharmaceutical companies, we all have a role to play. The series of 
hearings being held by Congress can be a catalyst for this much-
needed collaboration.

    There are two indisputable truths that make this the exact right 
moment for change:

        1.  Medicines alleviate human suffering and reduce overall 
        system costs.

        2.  The horribly misaligned incentives within our health-care 
        system often prevent medicines from getting into the hands of 
        patients.

    Our health-care system is broken, and we need to fix it. The system 
needs to be simpler and more transparent. It needs to incentivize 
innovation while simultaneously ensuring access. Simply put, it needs 
to put patients--and their health--first.

    How will we know when the health-care system is fixed? When 
patients feel real relief at the pharmacy counter--the kind of relief 
that means cost will no longer be a determining factor in whether 
someone picks up, and adheres to, their prescription. Too often, 
Americans are forced to choose between buying a medication that will 
improve, extend or save their lives or paying their bills. Too often, 
they fill their prescriptions, but take less than the prescribed dose 
in an effort to save money. Too often, lower-cost, FDA-approved generic 
and biosimilar alternatives are not made available to patients who 
desperately need them.

    We must take bold actions to ensure these scenarios do not play out 
time and time again across America.

    Pfizer intends to be a productive participant in this policy making 
and has come to the table with solutions. As such, we would like to 
propose four ideas to drive meaningful reductions in costs for 
patients.
                    passing all rebates to patients
    Today's current drug rebate system is good for two things: driving 
up both drug list prices and consumer out-of-pocket costs. In fact, in 
2018, the average net price of Pfizer's medicines in the United States 
declined 1 percent. However, I am certain that patients using our 
medicines had a very different experience at the pharmacy counter since 
their costs in the current system are more closely related to the list 
price than the net price. This is impactful when patients pay a 
coinsurance or are in the deductible phase of their benefits coverage. 
In these instances, patients are being asked to pay an average of 10 
percent to 20 percent or more out of their own pockets for many Pfizer 
products.

    There are two reasons for this disconnect: changes in benefit 
designs are pushing more and more of the medicines' cost to the pockets 
of the patients, and none of the close to $12 billion of rebates that 
Pfizer paid in 2018 found their way to American patients. As long as 
rebates serve as profit drivers, we will continue to see a major 
disconnect between list prices and prices people pay at the counter.

    Pfizer supports reforms that would create a system in which 
transparent, up-front discounts benefit patients at the pharmacy 
counter, rather than a system driven by rebates that are swallowed up 
by companies in the supply chain.

    The way to alleviate sticker shock at the pharmacy counter is by 
changing the incentives in the supply chain so that more of the $150 
billion in negotiated rebates and discounts actually reach patients. 
This can be accomplished by applying the discounts paid by the 
pharmaceutical manufacturer to the price actually paid by patients at 
the pharmacy. In 2019, Pfizer expects to pay billions in rebates to 
ensure patients with pharmacy benefits coverage in Medicare Part D and 
patients in commercial plans have access to our medicines. If the 
proposed rule to share rebates with consumers at the point of sale is 
finalized, we estimate that seniors taking Pfizer medicines could save 
$270 on average per year, and up to $574 per year for certain Pfizer 
medicines, through lower cost sharing--and that would outweigh any 
premium increases.

    Research also shows that sharing discounts at the pharmacy counter 
could reduce total health-care spending, and that reductions in overall 
out-of-pocket costs would outweigh any premium increases.

    We realize that the transition away from rebates toward a point-of-
sale discount model will result in a lowering of our net prices. 
Despite this potential negative financial impact, we support efforts to 
eliminate rebates because we believe the new model will be good for 
patients.

    Importantly, we believe any reform should apply to all market 
segments as this will also lead to further reduction in list prices. A 
bifurcated market in which we eliminate rebates in government programs 
but maintain rebates for commercial plans will make it difficult for 
manufacturers to reduce list prices because it applies to all markets.

    We will work with other leaders in the healthcare sector to advance 
these reforms, and we're committed to lowering list prices if the 
rebate rule applies to the commercial market.
                          less value, less pay
    Pfizer supports the move to value-based health care and is prepared 
to stand behind the benefits that our medicines deliver to patients and 
to the United States health-care system.

    Medical science is advancing so rapidly that payment models simply 
haven't been able to keep up. That's why Pfizer is focusing not only on 
scientific innovation, but also on commercial innovations that will 
allow us to get breakthrough medicines into the hands of patients, 
while simultaneously holding all participants in the system--including 
Pfizer--accountable for the health outcomes they help produce.

    This will require a fundamental shift in the way we think about the 
value that medicines deliver and how all participants in the system are 
reimbursed with regard to that value. It will also require the 
evolution of insurance designs to advance value-based insurance plans 
that removebarriers to high-value treatments.

    Imagine a system in which hospitals are rewarded for keeping 
patients from being readmitted; where physicians get paid more to 
prevent disease than they do to simply treat it; and where companies 
like Pfizer get paid based on the number of strokes we prevent or the 
number of cancer patients who go into full remission, rather than the 
number of pills we sell.

    In such a system, if our medicines do not produce results, we would 
be paid less. And if they do produce results, we would be paid more. If 
done correctly, these arrangements--focused on the appropriate 
therapeutic areas--can align the interests of patients, health plans 
and biopharmaceutical companies around one shared goal: ensuring 
positive health outcomes for the patient.

    To make this a reality, we need Congress's help to remove the 
roadblocks in the current system for the good of patients. I understand 
several members of this committee are drafting a legislative effort to 
pave the way for broader adoption of outcomes-based arrangements, and 
we applaud these efforts.
             capping seniors' out-of-pocket medicine costs
    Patients are increasingly being required to take on a bigger share 
of their medicines' costs, and that is particularly true when it comes 
to innovative and expensive treatments. Today, patients are made to pay 
on average 14 percent of the cost of their medicines, but only 3 
percent of the costs associated with hospital stays.

    This is forcing patients to forgo taking needed medications, to cut 
their pills in half, or to limit their doses in ways that are not 
medically prescribed. In fact, there is evidence that at least a 
quarter of new Medicare Part D prescriptions are abandoned at the 
pharmacy counter if beneficiaries are asked to pay $50 or more, which 
unfortunately is often the case. This number can exceed 50 percent for 
new prescriptions.

    This is bad not only for patients, but also for overall health-care 
system cost. Patients who do not take their medications often end up in 
the hospital, costing the health-care system much more. This needs to 
be fixed.

    Excessive cost-sharing is one of the greatest barriers to patient 
adherence and leads to more frequent discontinuation of therapy. While 
spending on medicines has been growing at a slower rate than in prior 
years, the number of patients with high deductible plans and high co-
insurance are growing rapidly. Since 2009, enrollment in high 
deductible plans has grown 250 percent, and since 2010 the number of 
patients exposed to high specialty tiers has grown 60 percent. In fact, 
I've heard from several members of this committee that their 
constituents--or they themselves--have recently gone to the pharmacy 
counter only to be shocked by an excessively high co-pay. That's why 
the time is now to review cost-sharing burdens in the Medicare 
prescription drug program and to take steps to ensure seniors don't 
have to make the difficult decision of forgoing their needed 
prescription.

    We commit to working with the committee on meaningful policy 
solutions that remove the burdens seniors face in paying for their 
medicines, and we believe an important first step is capping the out-
of-pocket costs seniors experience in the Medicare drug program.
            knocking down barriers to lower-cost biosimilars
    Medicines are the only segment of the health-care system with a 
built-in cost containment mechanism. When a medicine's patent expires, 
lower-cost generics are made available, often at just 5 percent of the 
cost of the original branded product.

    This system is working well for generic drugs. In fact, nine out of 
10 drugs sold in the U.S. today are lower-cost generics. However, the 
system is not yet working in the biologics space where the adoption of 
biosimilars is facing resistance.

    Establishing a robust biosimilars market can help to lower the 
overall health-care costs in the United States, and Pfizer is committed 
to bringing these more affordable treatment options to patients. That's 
why we must incentivize the use of biosimilars, which can be as much as 
40 percent less expensive than the branded biologic for Medicare 
patients.

    Unfortunately, adverse incentives that favor higher-cost originator 
biologics are keeping biosimilars from reaching patients. In many 
cases, payers decline to include lower-cost biosimilars or generics in 
their formularies because they would risk losing the rebates they can 
get by covering higher-cost medicines. I can't think of a more 
concerning example of a broken U.S. healthcare system that is directly 
impacting the pocketbooks of Americans.

    We have also witnessed exclusionary contracting or misleading 
marketing practices that mischaracterize important elements of 
biosimilar criteria. This creates doubt and confusion among patients, 
and it must end. Interestingly, the rebate reform I referenced earlier 
would go a long way toward removing the perverse incentives that lead 
to such exclusionary contracts.

    At Pfizer, we believe there are several solutions that could help 
patients and providers share savings associated with biosimilars and 
reduce costs to the Medicare program. Let me touch on two:

          A Shared Savings Biosimilars Model: Congress could direct 
        the CMS Innovation Center (CMMI) to test a biosimilar ``shared 
        savings'' approach in which Medicare savings associated with 
        prescribing a biosimilar, as compared to a reference 
        biological, would be shared with providers.

          Reduced Patient Cost Sharing for Biosimilars: CMS could 
        provide reduced or zero-dollar cost sharing for biosimilars for 
        patients for a certain period.
                                closing
    In 2018, we estimate \1\ that Pfizer vaccines protected more than 
65 million babies and elderly patients; our medicines helped reduce the 
risk of heart attack or stroke for more than 48 million cardiovascular 
patients; and oncologists used our therapies to treat more than 1.2 
million people battling cancer.
---------------------------------------------------------------------------
    \1\ Patient counts are estimates derived from multiple data 
sources.

    Overall more than 784 million people around the world used a Pfizer 
medicine or vaccine to improve their health and, in many cases, save 
---------------------------------------------------------------------------
their lives.

    These are staggering and humbling numbers. More important, they 
represent real people; real people who rely on our innovations. They 
also serve as a reminder that we--like our industry peers--are among 
the biggest contributors of good to humanity.

    This is why we come to work every day. It's why the researchers in 
our labs in California, Connecticut, Massachusetts and New York work 
day-in and day-out to perfect a formula. It's why our manufacturing 
colleagues in Georgia, Kansas, Michigan, Missouri, North Carolina, 
Ohio, Pennsylvania and Wisconsin--many of whom are represented by 
members of this committee--work to ensure the reliable supply and 
highest standards of quality of our products.

    And it's why we are here today to work with our peers, other 
participants in the healthcare system, and Congress to find ways to 
ensure the patients who need our medicines can access them so our 
industry's breakthroughs can continue to change patients' lives.

                                 ______
                                 
    Questions Submitted for the Record to Albert Bourla, DVM, Ph.D.
               Questions Submitted by Hon. Chuck Grassley
    Question. At the hearing, you testified that Pfizer does not 
withhold samples from generic manufacturers in order to block generic 
versions of your drug from entering the market. You also expressed your 
support for the ``Creating and Restoring Equal Access to Equivalent 
Samples Act,'' also known as the CREATES Act.

    However, the FDA has a list on its website which identifies 
reference listed drug (RLD) access inquiries where brand manufacturers 
may have prevented generic companies from obtaining samples of products 
necessary to support FDA approval. Pfizer is on this FDA list. This 
would appear to contradict your testimony at the hearing that Pfizer 
has not withheld samples of their products to delay generic 
competition.

          Could you please explain in detail why Pfizer is on the FDA 
        list?
          Could you please explain in detail the discrepancy between 
        your testimony and the FDA list?
          Has Pfizer ever blocked access to samples?

    Answer. As a patient-focused company and leading manufacturer of 
innovative, generic, and biosimilar medicines, Pfizer supports 
innovation and a strong, competitive marketplace. Consistent with these 
values, Pfizer does not block generic manufacturers from purchasing our 
products, and it has never been our policy to do so. Generic 
manufacturers are treated the same as any other customer seeking to 
purchase our products. Pfizer is not aware of any current, unfulfilled 
requests from a generic manufacturer to purchase a Pfizer product.

    Generic manufacturers seeking to purchase Pfizer products should 
request the product from Pfizer's authorized distributors or, if the 
product is not available at a distributor, from Pfizer directly, the 
same as any other Pfizer customers. Pfizer's website includes a list of 
our authorized distributors, from which customers (including generic 
companies) may purchase most Pfizer products (see https://www.
pfizer.com/products/medicine-distributors). For products that are not 
available via our authorized distributors and that are not in extreme 
drug shortage or unavailable due to a recall, customers can contact 
Pfizer's Customer Service center at 1-800-TRY-FIRST (1-800-879-3477) to 
purchase product directly from Pfizer. The telephone number for 
Pfizer's Customer Service center is also included on our website at 
https://www.pfizer.com/contact. Pfizer makes its products available for 
sale to appropriately licensed entities at Pfizer's listed price and on 
Pfizer's standard terms of sale. We do not have any agreements with 
authorized distributors that block the sale of Pfizer's products to 
generic manufacturers.

    Regarding the FDA List (the List), while Pfizer supports FDA's (the 
agency) goal of providing transparency, Pfizer is concerned that the 
List lacks certain key information and context and, as currently 
presented, may create the misleading impression that all products on 
the List are the result of bad faith attempts to block generic 
manufacturer access to samples. The appearance of a product on the FDA 
List means only that a generic manufacturer informed the agency at some 
point in time that it was having difficulty purchasing the listed 
product. FDA's own disclaimer states that the agency has not 
independently investigated or confirmed whether a generic manufacturer 
actually made a request to purchase product, and to whom.\1\ The FDA 
List also lacks several important pieces of information that would 
enable a New Drug Application (NDA) holder to investigate its 
appearance on the List. The List does not include: (1) which generic 
manufacturer made the request; (2) when and to whom the generic 
manufacturer made the request (e.g., to a wholesaler or directly to the 
NDA holder); (3) whether the generic manufacturer that made the inquiry 
was thereafter able to obtain product; and (4) any reason(s) why a 
generic manufacturer may not have been able to obtain product (e.g., a 
recall). Finally, Pfizer notes that FDA does not currently inform an 
NDA holder in real time when a generic manufacturer notifies the agency 
that it is having difficulty obtaining product. Had the agency informed 
Pfizer at the time it received the inquiries noted on the FDA List, 
Pfizer could have then undertaken its own efforts to resolve the issue. 
Pfizer communicated its concerns about the FDA List to the agency in 
May 2018. For your information we have included Pfizer's letter to FDA 
on this topic and the agency's response (see Exhibits 1 and 2 in the 
Appendix).
---------------------------------------------------------------------------
    \1\ (https://www.fda.gov/Drugs/DevelopmentApprovalProcess/
HowDrugsareDevelopedandAp
proved/ApprovalApplications/AbbreviatedNewDrugApplicationANDAGenerics/
ucm607738.htm).

    There are three new drug applications owned by Pfizer on the FDA 
List: Embeda (NDA 022321), Tikosyn (NDA 020931) and Hemabate (NDA 
017989). Embeda offers a good example of the List's shortcomings. 
Pfizer acquired King Pharmaceuticals (the previous NDA holder of 
Embeda) in March 2011, and two weeks later determined that Embeda 
needed to be recalled from the U.S. market due to stability issues. 
After diligently addressing the issues that led to the recall, Pfizer 
relaunched Embeda to the U.S. market in January 2015, and it is 
available for purchase via Pfizer's authorized distributors. However, 
one consequence of the recall was that Embeda was not available in the 
U.S. market for almost 4 years which may explain why a generic 
manufacturer had a problem obtaining it during those years. The FDA 
List does not specify when the generic manufacturer's inquiry regarding 
Embeda was made nor does the FDA List indicate that several generic 
applications for Embeda had been submitted to FDA in 2010 (which means 
that before the recall, several generic manufacturers were successfully 
able to purchase Embeda, conduct the necessary testing, and file 
Abbreviated New Drug Applications (ANDAs)). Pfizer has not identified 
any recent inquiries from generic manufacturers seeking to purchase 
---------------------------------------------------------------------------
Embeda that have not been fulfilled.

    The circumstances around Tikosyn also illustrate the List's 
shortcomings. Pfizer was able to identify a single inquiry made by a 
generic manufacturer directly to Pfizer to purchase Tikosyn in 2014. At 
that time, Tikosyn was subject to an FDA imposed Risk Evaluation and 
Mitigation Strategies (REMS) with Elements to Assure Safe Use 
(``ETASU'') that restricted distribution, so Pfizer responded by asking 
the manufacturer to obtain written confirmation from the FDA that 
Pfizer's provision of the product to the generic manufacturer would not 
be considered a violation of its REMS. The generic manufacturer did not 
contact Pfizer further, and Pfizer never received any written 
correspondence from the agency. FDA subsequently removed the REMS for 
Tikosyn in 2016, and multiple generic versions of Tikosyn are now 
approved, the first generic approval occurring in June 2016. This 
context is not reflected in FDA's List.

    Finally, with respect to Hemabate, this product was previously 
subject to certain restrictions on distribution (i.e., it was sold only 
to customers with medical and surgical intensive care centers) to 
ensure its safe and appropriate use. This distribution approach was 
established by the previous NDA holder (Pharmacia) and it continued 
following Pfizer's acquisition of Pharmacia in 2003. Pfizer 
discontinued this approach in early 2018 after determining that it was 
no longer necessary, and this product is now available through our 
authorized distributors. During the time when Hemabate was under 
restricted distribution, it was not available at Pfizer's authorized 
distributors, but had a generic manufacturer approached Pfizer's 
Customer Service center directly, we would have been able to address 
the inquiry. Pfizer's Customer Service was not able to identify any 
specific requests from a generic manufacturer to purchase Hemabate that 
have not been fulfilled.

    We hope that this information explains the apparent discrepancy 
between Mr. Bourla's testimony and the appearance of these Pfizer 
products on the FDA List, and demonstrates Pfizer's diligence on these 
issues and commitment to a competitive marketplace.

    Question. The Department of Health and Human Services' proposed 
rule, ``Fraud and Abuse; Removal of Safe Harbor Protection for Rebates 
Involving Prescription Pharmaceuticals and Creation of New Safe Harbor 
Protection for Certain Point-of-Sale Reductions in Price on 
Prescription Pharmaceuticals and Certain Pharmacy Benefit Manager 
Service Fees,'' envisions that drug manufacturers will offer up-front 
discounts rather than the back-end rebates that are now commonly 
provided. Some observers argue that a 1996 court case called into 
question whether manufacturers could offer up-front discounts, 
resulting in today's rebate-based system. I've heard differing opinions 
as to whether the issues related to the initial court case are still 
relevant. If the HHS proposed rule is finalized, can you assure the 
committee that your company will offer up-front discounts? If not, why?

    Answer. Yes, if finalized, price concessions negotiated with 
intermediaries, including Pharmacy Benefit Managers (PBMs) and plan 
sponsors, will be provided as discounts that will be applied at the 
point of sale. These discounts will lower patient out-of-pocket costs 
since the net price will be used to determine the cost to the patient 
when they are in the deductible, co-insurance, and coverage gap phases 
of their benefits.

    Question. Please describe how you expect your company to respond to 
the HHS proposed rule to eliminate safe harbor protection for back-end 
rebates in Medicare Part D that is referenced above if it is finalized. 
Assuming you are confident that antitrust laws do not prevent your 
company from offering up-front discounts, specifically, do you envision 
that your company lowers the list price of a drug to the current after-
rebate net price, offer discounts equal to the current rebate amount, 
or a combination of both?

    Answer. If finalized, the rule will result in lower out-of-pocket 
patient costs at the pharmacy counter and help address the perverse 
incentives in the system that have been contributing to higher list 
prices for medicines. We realize that the transition away from rebates 
toward a point-of-sale discount model will result in a lowering of our 
net prices. Despite this potential negative financial impact, we 
support efforts to eliminate rebates because we believe the new model 
will be good for patients.

    As currently written, the proposed rule only applies to the 
Medicare and Medicaid managed care segments of the market. It will be 
important to have any rebate reform apply to both government programs 
and the commercial market as that will also lead to a lowering of list 
prices as well. A bifurcated market will make it more challenging for 
manufacturers to reduce list price since the commercial market covers 
more than 50 percent of Americans with insurance and represents over 
half of the business for most manufacturers.

    If the proposed rule is modified to apply to all market segments, 
we would evaluate the best options to arrive at a net price that 
ensures patients have access to our medicines. Decisions would be made 
on a product by product basis given that each therapeutic class has its 
own set of competitive and access dynamics. As such, we expect to use 
both list price reductions and up-front discounts to achieve these 
lower net prices. To ensure these benefits reach patients, it will be 
important for Congress to ensure that plans do not create new barriers 
or restrictions that hinder patient access and undermine the spirit of 
the rule.

    Question. To what extent are the back-end rebates your company 
currently offers contingent on the amount of market share realized for 
your drugs as a result of Part D plan formulary placement and other 
techniques?

    Answer. Pfizer's contracts with Part D Health Plans and PBMs 
negotiating on their behalf do not make rebates contingent on market 
share.

    Question. Please provide a breakdown of percentage of sales that go 
to each payer (including Medicare, Medicaid, private pay, other) and a 
similar percentage by volume of the total number of each drug compared 
to total volume. Please provide this data for the most recent year 
available.

    Answer. Pfizer's prescription pharmaceutical products are sold 
principally to wholesalers, and therefore the Company does not have 
sufficient visibility into wholesaler distribution at the channel level 
to provide responses as requested. We welcome the opportunity to 
discuss with your committee staff the confidential information 
requested and what we maintain in the ordinary course of business.

    Question. Do your companies hire consultants or lobbyists to 
promote products at State Medicaid Pharmacy and Therapeutics 
Committees?

    Answer. No.

    Question. To whom do you disclose advocacy activities surrounding 
State Medicaid programs, if at all?

    Answer. Pfizer is committed to the principle of transparency--the 
disclosure of activities reflecting participation in efforts of public 
interest. These activities include such areas as funding for 
educational activities, the status of Pfizer's U.S. pharmaceutical 
post-marketing commitments, Pfizer's pipeline of experimental 
medicines, the registration and reporting of results of clinical 
trials, political contributions in the United States and payments to 
U.S. health care professionals. The information we report includes 
grants to support independent medical education, support for 
fellowship, scholarship and visiting professorship programs, grants to 
patient organizations, medical and scientific associations, and 
academic or other medical centers, charitable contributions, health 
care-related support to civic organizations and health care-related 
non-promotional sponsorships to organizations. For descriptions of 
types of support, please visit https://www.pfizer.com/purpose/
independent-grants/transparency-in-grants. Any Medicaid specific 
advocacy funding we provide would be captured in these reports.

    Question. Please describe how the costs of programs are accounted 
for within your company's financial statements. Please also describe 
the types of market information, such as prescribing and use patterns, 
that your company collects from different types of patient assistance 
programs and patient hub services.

    Answer. Pfizer's patient assistance program is a charitable free 
drug program that provides commercially available Pfizer medicines free 
of charge to financially eligible uninsured and underinsured patients. 
Separate from the Pfizer patient assistance program, Pfizer also offers 
patient support programs, which are limited access reimbursement 
support offerings to patients to assist with obtaining access to and 
coverage of a prescribed Pfizer medicine.

    The product and administrative costs for the patient assistance 
program are charged against Pfizer's Selling, General and 
Administrative Expenses line in the income statement.

    Pfizer gathers data in the course of providing free drugs to 
patients via the patient assistance program. We can bucket data 
collection in several ways:

        (1)  Transactional data--Utilized to determine patient 
        eligibility to receive free access to a physician-prescribed 
        therapy.

        (2)  Operational data--The operational data is utilized to 
        provide free access to medicines to the eligible patient and 
        the following is reported at an aggregated level: (i) program 
        utilization trends; (ii) application processing trends; (iii) 
        patient coverage trends; (iv) channel utilization (distribution 
        versus pharmacy); (v) fulfillment and order processing days; 
        and (vi) call metrics.

    Pfizer gathers the following two categories of data when providing 
patient support programs:

        (1)  Transactional--Utilized to assist in accessing prescribed 
        therapy and to determine insurance coverage for the patient. 
        This information contains data such as the outcome of a 
        benefits investigation, information to determine the financial 
        need and eligibility for patient support, and disposition of 
        the patient case (i.e., sent to a specialty pharmacy for 
        fulfillment, sent to Pfizer patient assistance program, triaged 
        to other financial options, or rejected/denied).

        (2)  Operational--These fields could include primary and 
        secondary payers, out-of-pocket costs borne by the patient, 
        turnaround time to obtain insurance approval, prior 
        authorization requirements, number of cases requiring appeals, 
        and other data elements on access dynamics. In addition to 
        these elements, Pfizer will collect relevant adverse events as 
        required by Pfizer drug safety.

    Question. Please provide a list of all contributions since January 
1, 2014, that your company has made to any tax exempt organizations 
working on issues related to drugs within your product lines, including 
but not limited to patient groups, disease awareness groups, medical or 
professional societies, universities or hospitals, industry 
associations or leagues. For each contribution, please provide the name 
of the organization that received the donation, the date the donation 
was made, the amount of the donation, and a description of the purpose 
of the contribution (i.e., was the contribution for the general fund, a 
specific purpose to a specific program, or continuing medical 
education). Please also note whether the contribution was unrestricted 
or restricted; if it was restricted, please explain all restrictions. 
Finally, if your company maintains a foundation or other separate 
charitable arm, please provide the name of all such entities, and list 
all donations made from that entity or entities.

    Answer. Information about Pfizer's charitable giving is listed on 
Pfizer.com. Please see the annual reports dating back to 2008 available 
at https://www.pfizer.
com/purpose/independent-grants/transparency-in-grants, which include 
the recipient name, the contribution amount and the annual quarter in 
which it was made, and a description of the relevant program or 
project. This data is updated each quarter. Data from Q4 2018 is 
currently being analyzed and will be available at the end of March 
2019. The annual reports include various funding types and recipient 
types. However, in collating this data, Pfizer does not characterize 
the organizations as working on issues related to drugs within product 
lines, or contributions as restricted or unrestricted. Consequently, 
the requested data is not available in that format.

    Note that information regarding charitable contributions from the 
Pfizer Foundation is not included in these reports, so Pfizer has 
included a Pfizer Foundation Grant Summary as Exhibit 3. The Pfizer 
Foundation has been working to expand health-care access to people 
around the world for nearly 65 years. The impact of this work is 
significant and far-reaching, helping underserved individuals from 
diverse backgrounds in remote corners of the globe. Through the Pfizer 
Foundation's global health strategy, we provide grant and investment 
funding to support organizations and social entrepreneurs in an effort 
to improve health care delivery in low-and middle-income countries and 
increase access to health care for underserved communities.

    Question. Pay for delay agreements cost consumers and taxpayers 
billions in higher drug costs every year. The FTC has gone after drug 
companies that enter into these settlements where the brand pays the 
generic company to keep its lower cost alternative off the market. I'm 
the lead Republican sponsor of S. 64, the ``Preserve Access to 
Affordable Generics and Biosimilars Act,'' which would help put an end 
to these deals.

    Do you agree that these pay-off agreements keep drug costs high for 
patients because they delay competition?

    Answer. Pfizer wants to work with you on this issue because we 
agree that gaming the patent system is unacceptable. The company's 
patent settlements do not involve ``pay for delay.'' On the contrary, 
when Pfizer settles patent litigation with generic firms, it does so on 
terms that generally enable entry of generic competition earlier than 
the expiration of its patents and that do not involve unlawful reverse 
payments. Pfizer's patent settlements thus involve lawful compromises 
that accelerate patient access to lower cost generics relative to the 
expiration of its patents.

    Question. Has your company ever entered into these kinds of 
settlements with a generic company?

    Answer. No. On the contrary, when Pfizer settles patent litigation 
with generic firms, it does so on terms that generally enable entry of 
generic competition earlier than the expiration of its patents and that 
do not involve unlawful reverse payments. Pfizer's patent settlements 
thus involve lawful compromises that appropriately resolve patent 
disputes and accelerate patient access to lower cost generics relative 
to the expiration of its patents. While Pfizer has been the target of 
plaintiff lawyer driven class action lawsuits challenging certain of 
its settlements with generic companies, we believe these lawsuits are 
without merit and are vigorously asserting the pro-competitive nature 
of these settlements in court.

    Question. Do you support the pay for delay bill?

    Answer. Pfizer agrees that gaming the patent system is 
unacceptable. We hope to work with you on legislation that prohibits 
anticompetitive patent settlements that is prospective, clearly defines 
violations and what is deemed to be an improper settlement and does not 
presume all patent settlement agreements are per se illegal and 
anticompetitive. Laws or actions to restrict certain kinds of 
pharmaceutical patent settlements could prevent some pro-consumer 
settlements that bring generics to market prior to patent expiration--
patent settlements often include an agreement that enables generics to 
enter the market earlier than the date of patent expiration, speeding 
patient access to more affordable generic options.
                           rebate traps/walls
    Question. I'm increasingly concerned about the effect of so-called 
``rebate traps'' or ``rebate walls'' on patients' access to quality, 
lower cost medicine. I understand there is ongoing litigation 
challenging these practices as anti-competitive.

    Does your company engage in the bundling of rebates over multiple 
products? If so, why? And what benefit does the consumer gain from 
that?

    Answer. Pfizer does currently bundle rebates over multiple 
products. Pfizer does offer bundling arrangements to obtain formulary 
positions that allow patients to access our medicines that otherwise 
might be restricted.

    Question. Does your company view these practices as anticompetitive 
or harmful to patients' access to quality, lower cost medicine?

    Answer. Pfizer does not believe bundling is inherently 
anticompetitive and in certain circumstances can be procompetitive. 
However, Pfizer does not tie bundled rebates to blocking lower cost 
competitive agents and believes that when a firm with monopoly power 
uses such practices to block lower cost alternatives the conduct is 
anticompetitive.

    Question. If a policy were adopted to eliminate rebates, or to 
require that rebate savings be passed on to the consumer, would that in 
and of itself solve the issue of rebate ``traps'' and ``walls''? And 
would consumers benefit from such a policy?

    Answer. A policy that moves rebates to discounts would not in and 
of itself eliminate the ability of a market leader to block a lower 
priced medicine. In both Medicare and commercial, the Health Plan is 
still responsible for the majority of the drug cost and would therefore 
receive the majority of the discount. The Health Plan or PBM would 
still need to transition patients from the higher priced market leader 
to the lower priced product in order to realize the savings from the 
discount. Based on internal analysis, Pfizer expects that moving from a 
rebate to a discount model will weaken a market leader's ability to 
restrict other less expensive products, but it would not eliminate the 
possibility.
                              drug pricing
    Question. When setting the list price of a drug, does your company 
consider regulatory costs or compliance? If so, how specifically do 
those factors affect the list price of a drug? Please provide at least 
one specific example, if applicable, from your current product 
portfolio.

    Answer. The Food and Drug Administration is the primary regulatory 
body for the pharmaceutical industry and is largely focused on the 
safety, quality, and efficacy of medicines. The price of a new medicine 
is most directly influenced by the value that the medicine may bring to 
patients and society. Inherent in the value any product Pfizer brings 
to the market are the quality, safety, delivery, efficacy, and 
reliability of our medicines. These regulatory and compliance factors 
are part of the underlying investments to identify a product's value 
and are amongst the many factors we consider when we determine a launch 
price or make a decision to change a price.

    Question. When setting the list price of a drug, does your company 
consider the risk of liability or litigation? If so, how specifically 
do those factors affect the list price of a drug? Please provide at 
least one specific example, if applicable, from your current product 
portfolio.

    Answer. Liability and litigation are not primary considerations 
when setting the list price of a medicine; the value that a product may 
bring to patients and society is the most important factor considered.

                                 ______
                                 
                Questions Submitted by Hon. Pat Roberts
    Question. What role do you see value-based agreements (VBAs) 
playing in the effort to reduce prescription drug costs? What potential 
do these arrangements have to find the ``sweet spot'' between 
controlling costs to patients and encouraging innovation of new drugs?

    Answer. Value-based agreements (VBA) provide a framework for 
manufacturers to be compensated based on a product's value to patients 
and the overall health-care system. Although there are different 
constructs for VBAs, the basic premise is that the net price for a 
product will ultimately be derived based on an agreed upon performance 
metric (e.g., clinical, financial, adherence, etc.). Therefore, VBAs 
can play a role in reducing prescription drug costs by ensuring that 
net prices are linked to value.

    As we shift to a system that rewards value, manufacturers will be 
incentivized to focus research and development (R&D) investments in 
disease areas where there are unmet needs, to focus on best in class or 
first in class medicines, and to design trials that provide the 
necessary evidence to demonstrate the value of a medicine beyond the 
regulatory standards of safety and efficacy to include the evidence to 
support reimbursement. If manufacturers deliver medicines of value, the 
system will reward the manufacturer which encourages innovation of new 
drugs.

    Question. How can VBAs help lower what patients pay out-of-pocket?

    Answer. Value-based agreements (VBA) provide a framework for 
manufacturers to be compensated based on a product's value to patients 
and the overall health-care system. There are many different types of 
VBAs including those based on clinical and/or financial performance 
metrics for a product. Based on the outcomes achieved, payers use this 
information to inform how they cover products. Products that perform 
better should be covered in a more favorable manner which often 
includes lower out-of-pockets costs for patients which is a benefit to 
patients in the near term. In the long term, patients can also benefit 
from other savings either directly, (e.g., reducing spending on other 
medications, lowering medical costs from reduced hospitalizations, 
doctor's visits, etc.), or indirectly through lower premiums based on 
reductions in total cost of care.

    Question. Can Congress do more to allow for and encourage the use 
of VBAs?

    Answer. VBAs are in the very early stages of development in the 
United States. Many payers and manufacturers have tested different 
concepts, but to date VBAs have not achieved scale. There are multiple 
reasons why VBAs represent a small fraction of manufacturer/payer 
contracts (e.g., access to data, difficult and costly to administer, 
etc.). There are certain aspects of the current U.S. regulatory 
landscape that are perceived by many as not only complicating VBA 
implementation but in some cases limiting their rapid uptake. 
Stakeholders have frequently identified two key regulatory hurdles as 
limiting the expanded adoption of VBAs: (i) the Anti-Kickback Statute 
and (ii) the Medicaid Best Price calculation requirement. While these 
regulations serve important roles within the current volume-based 
reimbursement system they do not contemplate innovative value-based 
arrangements which have resulted in a lack of clarity on how to account 
for these under the current regulatory framework. Ultimately, an 
expansion of VBAs will require reforms to existing regulations that 
enable more flexibility in designing VBAs.

                                 ______
                                 
              Questions Submitted by Hon. Michael B. Enzi
    Question. More than 10 years ago, I worked on a bipartisan basis 
with my good friends Ted Kennedy and Orrin Hatch to develop a 
biosimilars approval pathway. One of the difficult things was 
accounting for the differences between biosimilars and generics. I have 
said before that if a drug was a three-bedroom, two-bath home, a 
biologic would be a skyscraper. The size and complexity of the items 
are just that different. I understand that it is much harder to build a 
skyscraper without blueprints than a house. Even though the science has 
come a long way since then, there aren't as many biosimilars on the 
market as we might have hoped. Do you think the incentives in the law 
appropriately account for the differences between biosimilars and 
generics?

    Answer. The Biologics Price Competition and Innovation Act (BPCIA) 
created an abbreviated pathway for the licensure of biosimilars, 
including interchangeable biologic products, and created the framework 
biosimilar applicants and reference product sponsors use to resolve 
patent disputes. There are currently seven biosimilars on the market in 
the United States, and there are a number of biosimilars currently in 
development. The FDA has approved a total of 18 biosimilars to date. 
Nevertheless, the success of the BPCIA lies in the increased use of 
these products, which will provide savings to both the patient and the 
taxpayer.

    To date, there have been two key policies that have helped support 
the biosimilars marketplace: 340B pass-through status for biosimilars 
and the separate billing/J code policy for biosimilars.

    The separate billing/J code policy for biosimilars has aided in the 
prompt reimbursement of biosimilars for physicians, which is critical 
in supporting uptake of biosimilars. The separate billing/J code also 
provides Congress and CMS with transparency on the average sales price 
of the biosimilar versus the reference biologic. Below is a table 
outlining the latest Medicare published average sales prices for the 
reference biologic Remicade and both of the biosimilars on the market 
for Remicade, Pfizer's Inflectra and Merck's Renflexis.\2\ It is 
important to note that the average sales price (ASP) for both 
biosimilars is lower than the ASP of the reference biologic. Yet, the 
market share of the Inflectra biosimilar remains at 6 percent in open 
systems (which excludes the VA and Kaiser, which are closed systems 
where the insurer is the payer, the prescriber and the provider).
---------------------------------------------------------------------------
    \2\ https://www.cms.gov/Medicare/Medicare-Fee-for-Service-Part-B-
Drugs/McrPartBDrugAvg
SalesPrice/2019ASPFiles.html.


------------------------------------------------------------------------
                                   Q4 2018 CMS  Q1 2019 CMS  Q2 2019 CMS
                       HCPCS Code      ASP          ASP          ASP
------------------------------------------------------------------------
Remicade (reference         J1745      $743.71      $723.10      $677.60
 biologic)
------------------------------------------------------------------------
Inflectra                   Q5103      $569.01      $529.37      $502.72
 (biosimilar)
------------------------------------------------------------------------
Renflexis                   Q5104      $599.20      $575.64      $552.00
 (biosimilar)
------------------------------------------------------------------------

    The 340B pass-through policy for biosimilars has been another 
positive policy to support uptake of biosimilars in 340B hospitals. The 
340B pass-through policy provides a temporary ``level playing field'' 
for the biosimilar and the reference biologic. Under the reimbursement 
model of ASP + x%, providers are incentivized to use a higher cost 
product to drive a higher ``+ x%'' reimbursement. As in the case of 
biosimilars, when the biosimilar has a lower ASP the reimbursement is 
lower to the health-care provider/340B hospital. The pass-through 
policy provides temporary reimbursement parity for lower cost 
biosimilars. This policy has encouraged 340B hospitals to adopt 
biosimilars and gain experience and confidence in using them.

    Despite these current policies, other adverse incentives that favor 
higher-cost originator biologics are keeping biosimilars from reaching 
patients. In many cases, payers decline to include lower-cost 
biosimilars or generics in their formularies because they would risk 
losing the rebates they could receive by covering higher-cost 
medicines.

    Question. I know there are proposals to essentially pay more for 
biosimilars to make them more attractive, but that is not exactly what 
we were intending when we wrote the law. Can you talk about adverse 
incentives in the market and any barriers to market penetration that we 
might address to help improve patient access to these lower cost 
products?

    Answer. Ninety percent of the medicines Americans take are generics 
and competition from these drugs keeps prices low in most cases. The 
biologics market, where some of the most expensive drugs exist, needs 
similar competition. The market today has already seen demonstrated 
savings as high as 40 percent relative to the branded product. In 
Europe, biosimilars have obtained a market share of over 60 percent on 
some products. However, in the United States, our biosimilar, 
Inflectra, has captured only 6 percent, despite the fact that its 
average selling price (ASP) is more than 25 percent lower than the 
originator product. With more competition, Pfizer hopes even further 
savings can be realized. We believe some of the adverse incentives and 
barriers to market penetration include:

        1.  The Rebate Trap: Brand-name biologic companies are using 
        maneuvers to block biosimilar competition such as higher 
        rebates and exclusionary contracts.

        2.  Misinformation: We believe that some physician and patient-
        directed materials created by brand companies mischaracterize 
        biosimilars, creating doubt and confusion about the safety and 
        efficacy of biosimilars. As defined by statute, an approved 
        biosimilar must be highly similar to and have no clinically 
        meaningful differences from the reference product and must have 
        the same mechanism of action (to the extent the mechanism(s) of 
        action of the reference product are known) as the reference 
        product. Thus, by definition, biosimilars are safe and 
        efficacious treatments relative to the reference product and 
        must work in the same way as the reference product. Any 
        information disseminated by reference product sponsors to 
        suggest or imply otherwise should be promptly addressed by the 
        FDA.

        3.  Need for incentives: Legislative ideas to promote 
        biosimilar uptake could include a shared savings biosimilar 
        model; reduced patient cost sharing for biosimilars.

           Although the biosimilar market in the United States is still 
        relatively new, Pfizer's experience has been that 
        anticompetitive conduct by brand-name biologic manufacturers, 
        combined with the lack of policy measures to support 
        appropriate uptake of biosimilars, have contributed to a slow 
        uptake. Therefore, we encourage you to consider measures to 
        help incentivize the use of biosimilars, which can 
        substantially lower Medicare costs with demonstrated savings to 
        date as high as nearly 40 percent relative to the branded 
        biologic.

           In addition to stopping anticompetitive behavior (either 
        through government enforcement or in the courts through private 
        litigation), some key policy initiatives we believe will 
        support the uptake of biosimilars in the United States include:

            Waiver of Part B Patient Coinsurance for Biosimilars for a 
        certain period of time. CMS should waive Part B patient 
        coinsurance amounts for biosimilars. Cost-sharing changes could 
        be applied at the Healthcare Common Procedure Coding System 
        (HCPCS) level. This would not change the overall payment for a 
        biosimilar; however, it would change the beneficiary's payment 
        percentage.

            CMS should pursue a CMMI model designed to increase access 
        to biosimilars, including a ``shared savings'' model whereby 
        Medicare savings associated with prescribing a biosimilar, as 
        compared to a reference biological, would be shared with 
        providers.

            CMS should maintain the current biosimilar pass-through 
        status as this provides biosimilars with a ``level playing 
        field'' with their higher priced reference biologic 
        competitors.

            CMS should create payment incentives for plans by 
        contracting with a measure developer for a biosimilar use 
        measure for the STARS program, which would correct other 
        adverse incentives for biosimilar uptake for Medicare Advantage 
        plans.

                                 ______
                                 
                Questions Submitted by Hon. John Cornyn
    Question. We continue to hear that rebates negotiated off of the 
list price of a drug are both good and bad.

    Pharmacy benefit managers and plans have argued that rebates are 
used to lower premiums across the board and that it is the best way to 
seek a price concession on otherwise expensive drugs.

    Your industry argues that these payers are insisting on higher 
rebates that can only be achieved by raising list prices.

    But patients often lose under this system, with out of pocket costs 
being tied to list price. Insulin patients appear to be routinely 
impacted by this perversity in the system.

    Please explain to the committee how your company would reduce list 
prices if rebates were no longer a part of the equation?

    Answer. If finalized, the rule would result in lower out-of-pocket 
patient costs at the pharmacy counter and help address the perverse 
incentives in the system that have been contributing to higher list 
prices for medicines.

    In 2019, Pfizer expects to pay billions of dollars in rebates to 
ensure patients with pharmacy benefits coverage in Medicare Part D and 
patients in commercial plans have access to our medicines. If the 
proposed rule to share rebates with consumers at the point of sale is 
finalized, we estimate that seniors taking Pfizer medicines could save 
$270 on average per year, and up to $574 per year for certain Pfizer 
medicines, through lower cost sharing--and that would outweigh any 
premium increases.

    As currently written, the proposed rule only applies to the 
Medicare and Medicaid managed care segments of the market. It will be 
important to have rebate reform changes apply to both government 
programs and the commercial market. A bifurcated market will make it 
more challenging for manufacturers to reduce list price since the 
commercial market covers more than 50 percent of Americans with 
insurance and represents over half of the business for most 
manufacturers.

    If the proposed reform is modified to apply to all market segments, 
we would evaluate the best options to arrive at a net price that 
ensures patients have access to our medicines. Decisions would be made 
on a product by product basis given that each therapeutic class has its 
own set of competitive and access dynamics.

    Question. What assurance can you provide that you would in fact 
lower your prices?

    Answer. If the rule is finalized consistent with the aforementioned 
concerns, Pfizer is confident patients will benefit from savings of any 
price concessions at the point of sale.

    Question. What actions should be taken to ensure that patients are 
actually seeing the benefits of lower out of pocket costs?

    Answer. We strongly support ensuring that patients receive the 
benefit of rebates at the pharmacy counter and look forward to working 
with Congress and HHS on this issue. We encourage Congress to ensure 
that plans do not impose new barriers or restrictions to access that 
undermine the spirit of the rule and prevent patients from benefiting 
from the savings.

    Question. If rebates are driving high list prices for drugs as drug 
manufacturers' claim, why do you think that Part B drugs, which have no 
PBM rebates, are also seeing significant price increases? Whose fault 
is that?

    There are rebates involved with infusion medicines (Medicare Part B 
drugs), and Pfizer is willing to engage with your staff in general 
terms to explain the relationship and negotiations between 
manufacturers and payers such as insurers and PBMs for drugs in this 
space.

    Pfizer also believes there are other ways to reform the Part B 
payment system to move away from incentivizing the use of more costly 
drugs. One solution we support for reforming Part B is a Competitive 
Acquisition Program (CAP) to allow vendors to deliver and bill Medicare 
for drugs, starting in a few cities. We believe this will inject 
competition into the program.

    Biosimilars are another solution. Pfizer is fully committed to the 
goals set by Congress to bring new biosimilars to market, ensuring that 
patients have access to a wide range of treatment options at a 
competitive, affordable price. The market today has already seen 
demonstrated savings as high as 40 percent relative to the branded 
product. With more competition, we hope even further savings can be 
realized.
                              rebate traps
    Question. Pfizer's biosimilar to Janssen's Remicade has struggled 
to gain market share, despite being priced at a significant discount to 
the biologic.

     Please explain the market challenges you are seeing with this 
product. How does the practice of drug companies ``bundling'' the 
prices of product portfolios and rebates associated with these drugs 
limit competition and access to lower-cost biosimilars?

    Answer. As more fully laid out in Exhibit 4, the primary barrier to 
Inflectra's uptake is an anticompetitive contracting scheme that 
targets both the payer (i.e., insurer) channel and the health-care 
provider (i.e., hospitals, clinics and doctors) channel. The 
centerpiece of the scheme is the ``rebate trap'' that uses pricing 
penalties (i.e., the loss of significant rebates) to coerce insurers to 
enter into exclusive deals that cover Remicade while effectively 
blocking Inflectra from coverage. Multi-
product bundling is just one aspect of the conduct. Despite bringing a 
lower-cost version of Remicade to market, this biosimilar has captured 
less than 10 percent of the market.

    Question. Do you attribute this to exclusionary contracts or 
``paying for position'' to keep your product off formularies? Please 
explain this practice and how it keeps lower-cost drugs out of the 
hands of patients.

    Answer. Pfizer attributes low uptake to an anticompetitive 
contracting scheme as described above in response to Question 1.

    This is particularly concerning not only because of the direct 
impact regarding the health-care system's spend, but also because it 
could become the playbook by which innovator biologics thwart entry by 
biosimilars in the future. This could inhibit significant competition 
to biologics going forward and act as a disincentive for companies to 
invest in developing biosimilars.

                                 ______
                                 
                Questions Submitted by Hon. Steve Daines
    Question. As an advocate for improving Montanans' access to low-
cost medications, I've been a champion of the Creating and Restoring 
Equal Access to Equivalent Samples (CREATES) Act, which would combat 
anticompetitive practices used by some brand-name pharmaceutical 
companies to block or delay competing generic drugs from entering the 
market.

    During the hearing when I asked if your company had ever withheld 
samples from generic manufacturers, you answered emphatically no. Yet, 
according to the Food and Drug Administration (FDA), generic drug 
makers have made inquiries with the agency claiming they were unable to 
access samples provided by Pfizer and AstraZeneca that are needed to 
conduct studies to produce low-cost generic drugs.

    Do you agree that denying generic drug manufacturers access to 
samples keeps drug costs high for patients due to lack of competition?

    Has your company refused to sell samples or placed any barriers in 
the way of generic drug makers acquiring samples?

    Are you aware of any outstanding requests for samples?

    How does your company work to prevent abuses in the sample system?

    Answer. As a patient-focused company and leading manufacturer of 
innovative, generic, and biosimilar medicines, Pfizer supports 
innovation and a strong, competitive marketplace. Consistent with these 
values, Pfizer does not block generic manufacturers from purchasing our 
products, and it has never been our policy to do so. Generic 
manufacturers are treated the same as any other customer seeking to 
purchase our products. Pfizer is not aware of any current, unfulfilled 
requests from a generic manufacturer to purchase a Pfizer product.

    Generic manufacturers seeking to purchase Pfizer products should 
request the product from Pfizer's authorized distributors or, if the 
product is not available at a distributor, from Pfizer directly, the 
same as any other Pfizer customers. Pfizer's website includes a list of 
our authorized distributors, from which customers (including generic 
companies) may purchase most Pfizer products (see https://www.
pfizer.com/products/medicine-distributors). For products that are not 
available via our authorized distributors and that are not in extreme 
drug shortage or unavailable due to a recall, customers can contact 
Pfizer's Customer Service center at 1-800-TRY-FIRST (1-800-879-3477) to 
purchase product directly from Pfizer. The telephone number for 
Pfizer's Customer Service center is also included on our website at 
https://www.pfizer.com/contact. Pfizer makes its products available for 
sale to appropriately licensed entities at Pfizer's listed price and on 
Pfizer's standard terms of sale. We do not have any agreements with 
authorized distributors that block the sale of Pfizer's products to 
generic manufacturers.

    Regarding the FDA List (the List), while Pfizer supports FDA's (the 
agency) goal of providing transparency, Pfizer is concerned that the 
List lacks certain key information and context and, as currently 
presented, may create the misleading impression that all products on 
the List are the result of bad faith attempts to block generic 
manufacturer access to samples. The appearance of a product on the FDA 
List means only that a generic manufacturer informed the agency at some 
point in time that it was having difficulty purchasing the listed 
product. FDA's own disclaimer states that the agency has not 
independently investigated or confirmed whether a generic manufacturer 
actually made a request to purchase product, and to whom.\3\ The FDA 
List also lacks several important pieces of information that would 
enable a New Drug Application (NDA) holder to investigate its 
appearance on the List. The List does not include: (1) which generic 
manufacturer made the request; (2) when and to whom the generic 
manufacturer made the request (e.g., to a wholesaler, directly to the 
NDA holder); (3) whether the generic manufacturer that made the inquiry 
was thereafter able to obtain product; and (4) any reason(s) why a 
generic manufacturer may not have been able to obtain product (e.g., a 
recall). Finally, Pfizer notes that FDA does not currently inform an 
NDA holder in real time when a generic manufacturer notifies the agency 
that it is having difficulty obtaining product. Had the agency informed 
Pfizer at the time it received the inquiries noted on the FDA List, 
Pfizer could have then undertaken its own efforts to resolve the issue. 
Pfizer communicated its concerns about the FDA List to the agency in 
May 2018. For your information we have included Pfizer's letter to FDA 
on this topic and the agency's response (see Exhibits 1 and 2 in the 
Appendix).
---------------------------------------------------------------------------
    \3\ (https://www.fda.gov/Drugs/DevelopmentApprovalProcess/
HowDrugsareDevelopedandAp
proved/ApprovalApplications/AbbreviatedNewDrugApplicationANDAGenerics/
ucm607738.htm).

    There are three new drug applications owned by Pfizer on the FDA 
List: Embeda (NDA 022321), Tikosyn (NDA 020931) and Hemabate (NDA 
017989). Embeda offers a good example of the List's shortcomings. 
Pfizer acquired King Pharmaceuticals (the previous NDA holder of 
Embeda) in March 2011, and two weeks later determined that Embeda 
needed to be recalled from the U.S. market due to stability issues. 
After diligently addressing the issues that led to the recall, Pfizer 
relaunched Embeda to the U.S. market in January 2015, and it is 
available for purchase via Pfizer's authorized distributors. However, 
one consequence of the recall, was that Embeda was not available in the 
U.S. market for almost 4 years which may explain why a generic 
manufacturer had a problem obtaining it during those years. The FDA 
List does not specify when the generic manufacturer's inquiry regarding 
Embeda was made nor does the FDA List indicate that several generic 
applications for Embeda had been submitted to FDA in 2010 (which means 
that before the recall, several generic manufacturers were successfully 
able to purchase Embeda, conduct the necessary testing, and file 
Abbreviated New Drug Applications (ANDAs)). Pfizer has not identified 
any recent inquiries from generic manufacturers seeking to purchase 
---------------------------------------------------------------------------
Embeda that have not been fulfilled.

    The circumstances around Tikosyn also illustrate the List's 
shortcomings. Pfizer was able to identify a single inquiry made by a 
generic manufacturer directly to Pfizer to purchase Tikosyn in 2014. At 
that time, Tikosyn was subject to an FDA imposed Risk Evaluation and 
Mitigation Strategies (REMS) with Elements to Assure Safe Use 
(``ETASU'') that restricted distribution, so Pfizer responded by asking 
the manufacturer to obtain written confirmation from the FDA that 
Pfizer's provision of the product to the generic manufacturer would not 
be considered a violation of its REMS. The generic manufacturer did not 
contact Pfizer further, and Pfizer never received any written 
correspondence from the agency. FDA subsequently removed the REMS for 
Tikosyn in 2016, and multiple generic versions of Tikosyn are now 
approved, the first generic approval occurring in June 2016. This 
context is not reflected in FDA's List.

    Finally, with respect to Hemabate, this product was previously 
subject to certain restrictions on distribution (i.e., it was sold only 
to customers with medical and surgical intensive care centers) to 
ensure its safe and appropriate use. This distribution approach was 
established by the previous NDA holder (Pharmacia) and it continued 
following Pfizer's acquisition of Pharmacia in 2003. Pfizer 
discontinued this approach in early 2018 after determining that it was 
no longer necessary, and this product is now available through our 
authorized distributors. During the time when Hemabate was under 
restricted distribution, it was not available at Pfizer's authorized 
distributors, but had a generic manufacturer approached Pfizer's 
Customer Service center directly, we would have been able to address 
the inquiry. Pfizer's Customer Service was not able to identify any 
specific requests from a generic manufacturer to purchase Hemabate that 
have not been fulfilled.

    We hope that this information explains the apparent discrepancy 
between Mr. Bourla's testimony and the appearance of these Pfizer 
products on the FDA List, and demonstrates Pfizer's diligence on these 
issues and commitment to a competitive marketplace.

                                 ______
                                 
                 Questions Submitted by Hon. Todd Young
         re-evaluating business strategies in foreign countries
    Question. Since taking office, President Trump has made reducing 
drug prices one of his highest priorities--and has repeatedly spoken 
about his frustration with the U.S. subsidizing the costs of 
pharmaceuticals for the rest of the world. He has gone so far as to 
issue proposals, like the International Pricing Index (IPI) Model, in 
an attempt to bring down prescription drug prices.

    With the increased scrutiny of the industry and of the drug supply 
chain as a whole in the United States, have any of your companies re-
evaluated your business strategy in foreign countries?

    Answer. Pfizer's purpose is breakthroughs that change patients' 
lives; all aspects of Pfizer's business model are infused with this 
purpose. It is Pfizer's priority to make our medicines and vaccines 
available and accessible to all patients who need them, regardless of 
where they live.

    Proposals to implement international reference pricing for the U.S. 
market would have far-reaching consequences to patient access, 
innovation and our business strategies both in the United States and in 
foreign countries.

    If the United States were to implement the proposed International 
Price Indexing (IPI) model, we believe that a change of this scale 
could be very disruptive, challenging our ability to reach patients 
both inside and outside of the United States in a timely manner while 
fulfilling commitments to our shareholders and further investing in 
R&D.

    Question. If not, then why?

    Answer. Pfizer agrees that more must be done to address foreign 
pricing differentials. We want to continue to work with policymakers on 
solutions to ensure other countries appropriately recognize the value 
of innovation. Pfizer supports the concept of ``shared value for 
innovation'' because it promotes global fairness. This means that all 
nations recognize the importance and benefits of medicines to patients 
and society and the significant investments required to develop them, 
and that all patients should benefit, no matter where they live.

    If foreign countries were to increase their support for shared 
value for innovation, American patients would benefit based on 
increased innovation, drug launches, competition and more access to new 
medicines.

    Question. If a proposal, like IPI, were implemented, would it force 
your companies to potentially ``walk away from the negotiating table 
when other countries demand low prices subsidized by America's 
seniors,'' as HHS Senior Advisor for Drug Pricing Reform John O'Brien 
has said?

    Answer. While the IPI could lead to potential situations in which a 
company would ``walk away'' as noted by John O'Brien, pricing is not 
the only determinant of reimbursement negotiations in foreign 
countries, many of which employ access controls, restricting patients' 
ability to receive new innovative medicines.

    We have concerns with the IPI model. The use of reference pricing 
is strongly associated with market and patient access delays in 
countries that have adopted reference pricing, among other cost-
containment mechanisms. Pfizer works with governments and health 
systems around the world to support patients' access to the medicines 
they need. We strongly believe that flexibility in our ability to set 
global prices improves access to medicines.

    Question. What are some of your ideas on how we can ensure 
Americans aren't shouldering the full cost of pharmaceuticals?

    Answer. Pfizer believes that developed countries have an important 
role to play in supporting global innovation ecosystems. As such, we 
would encourage the United States Government to continue to elevate the 
innovation agenda in multilateral discussions, with an emphasis on 
rewarding innovation in health-care delivery, science policy and 
pharmaceutical breakthroughs (e.g., through the G7). U.S. trade 
negotiations, such as those with Japan, also provide important 
opportunities for the United States to secure robust commitments that 
ensure countries protect intellectual property, provide fair market 
access for U.S. companies, and appropriately recognize the value of 
innovation.

    Pfizer also believes that there are other ways to reform the Part B 
payment system to move away from incentivizing the use of more costly 
drugs. One solution we support for reforming Part B is a Competitive 
Acquisition Program (CAP) to allow vendors to deliver and bill Medicare 
for drugs, starting in a few cities. We believe this will inject 
competition into the program.

    Biosimilars are another solution. Pfizer is fully committed to the 
goals set by Congress to bring new biosimilars to market, ensuring that 
patients have access to a wide range of treatment options at a 
competitive, affordable price. The market today has already seen 
demonstrated savings as high as 40 percent relative to the branded 
product. With more competition, Pfizer hopes even further savings can 
be realized.
              foreign countries' pricing and reimbursement
    Question. President Trump and Secretary Azar have both repeatedly 
described their frustrations with ``foreign freeloading'' of U.S. drugs 
in the last year.

    ``When foreign governments extort unreasonably low prices from U.S. 
drug makers, Americans have to pay more to subsidize the enormous cost 
of research and development. . . . It's unfair and it's ridiculous, and 
it's not going to happen any longer.''

    Do you agree that because of foreign countries' pricing and 
reimbursement systems, U.S. patients and innovators are shouldering the 
burden for financing medical advances?

    Answer. Pfizer agrees that more must be done to address foreign 
pricing differentials. Wealthy countries should reimburse innovative 
medicines based on fair value. As stated above, ``foreign free-
loading'' has a significant impact on the U.S. biopharmaceutical 
industry's investments in continued innovation. If the United States 
secures agreements that ensure countries protect intellectual property, 
provide fair market access for U.S. companies, and appropriately 
recognize the value of innovation, this will help ensure U.S. patients 
continue to have access to innovative medicines.

    Question. How do foreign countries' pricing and reimbursement 
systems affect our prescription drug costs?

    Answer. The U.S. health-care system offers patients more choice and 
faster availability of innovative medicines. While government-run 
health systems aim to provide care to their people, they are often 
challenged to provide fast and easy access to the latest innovations. 
These governments often have to make choices between paying for health 
care and other government priorities.

    The United States allows companies and providers to set prices that 
reflect the benefits to patients and societies. This includes ensuring 
that health-care professionals and patients have choices for 
individualized care, that there is competition among companies, and 
that their expectations for access to the latest medical advances are 
met.

    Some developed countries rely on price controls and other 
government regulations to set the prices of health care, including 
medicines. This may result in some lower prices but can also result in 
restrictions on who is eligible to receive a covered medicine. A recent 
op-ed in The Wall Street Journal pointed out that of the 45 new drugs 
that FDA approved in 2015, all were covered by Medicare in the United 
States in 2017, but only 19 in France, 13 in Canada and 11 in 
Australia.\4\
---------------------------------------------------------------------------
    \4\ https://www.wsj.com/articles/how-to-reduce-prescription-drug-
prices-first-do-no-harm-1155
0100537.

    However, prices are not always higher in the United States. Nine 
out of ten drugs that patients pick up at the pharmacy are generics, 
and these drugs are less expensive than they are in Europe, Japan, 
China or many countries around the world. The U.S. system is the most 
---------------------------------------------------------------------------
efficient system for delivering lower-cost generics to patients.

    Pfizer supports the concept of ``shared value for innovation'' 
because it promotes global fairness. This means that all nations 
recognize the importance and benefits of medicines to patients and 
society and the significant investments required to develop them, and 
that all patients should benefit, no matter where they live.

    If foreign countries were to increase their support for shared 
value for innovation, American patients would benefit based on 
increased innovation, drug launches, competition and more access to new 
medicines.

    Question. Are foreign governments taking note of the concerns being 
raised by the Trump administration and have they responded in any way?

    Answer. Pfizer believes that other governments are indeed taking 
note of the administration's focus on health-care spending.

    Question. Has there been any noticeable change in any of our trade 
agreements since these concerns have been raised by the Trump 
administration?

    Answer. The Trump administration recently signed the U.S.-Mexico-
Canada Agreement (USMCA), which includes important commitments that 
will help companies like Pfizer continue to innovate to bring new 
therapies to patients. For example, the agreement includes a commitment 
to provide 10 years of regulatory data protection for biologics. This 
commitment had not been included in any trade agreement negotiated 
prior to USMCA and is an important achievement. The Trump 
administration is also pursuing new bilateral trade negotiations with 
Japan, the EU, and the UK; because the negotiations have not yet 
concluded, however, it is premature to comment on how those agreements 
may compare to other U.S. trade deals.
                  medicaid closed formulary proposals
    Question. In an attempt to bring down drug costs, various States 
have been exploring whether to exclude certain drugs from its Medicaid 
program. For example, the State of Massachusetts' recently asked CMS 
for permission to create a closed formulary where the State Medicaid 
program would pick at least one drug per therapeutic class. CMS denied 
their waiver request citing violation of Federal law, but this proposal 
does bring up important questions on how to contain drug prices in 
State Medicaid programs.

    If the principles of the Medicare Part D program--including the 
necessary patient protections--were applied to State Medicaid programs, 
do you think it lower drugs costs while ensuring access to patients?

    Answer. Pfizer supports efforts to ensure patients have access to 
medicines. Studies suggest that allowing more choice of medications has 
positive results for patients: lowering the chances of drug 
interactions and adverse events and increasing the efficacy of 
treatment.\5\ Years of research have also shown that limiting 
formularies correlates to poor medication adherence outcomes.\6\ 
Studies featuring Medicaid recipients with severe health conditions 
indicate that in many instances, these restrictions can result in 
negative health outcomes and other outcomes (such as increased 
incarceration rates) without generating program savings or other 
intended benefits (and sometimes increasing overall State costs).\7\
---------------------------------------------------------------------------
    \5\ See, e.g., DiMasi, ``Competitiveness in follow-on drug R&D: a 
race or imitation?'', 10 Nat. Rev. Discov. 23-27 (Jan. 2011); Turner 
et. al, ``Parsing Interindividual Drug Variability: An Emerging Role 
for Systems Pharmacology,'' Wiley Interdiscip. Rev. Syst. Biol. Med. 
221-41 (2015); Mullins et. al, ``Persistence, Switching, and 
Discontinuation Rates Among Patients Receiving Sertraline, Paroxetine, 
and Citalopram,'' 25 Pharmacotherapy 660-67 (2005).
    \6\ See, e.g., Happe et. al, ``A Systematic Literature Review 
Assessing the Directional Impact of Managed Care Formulary Restrictions 
on Medication Adherence, Clinical Outcomes, Economic Outcomes, and 
Health Care Resource Utilization,'' 20 Manag. Care Spec. Pharm. 677-84 
(2014).
    \7\ See, e.g., U.S.C. Schaffer, ``Medicaid Access Restrictions on 
Psychiatric Drugs: Penny-Wise or Pound Foolish?'', (Feb. 2015), http://
healthpolicy.usc.edu/documents/USC%20Issue%20Brief
%20No.%202%20Final.pdf (indicating increased incarceration rates 
associated with certain access restrictions); Lu, et. al, ``Unintended 
Impacts of a Medicaid Prior Authorization Policy on Access to 
Medications for Bipolar Illness,'' 48 Medical Care 4 (Jan. 2010) 
(finding that while a prior authorization policy in Maine Medicaid was 
associated with a marked decrease in rates of initiation of bipolar 
treatments associated with reduction in initiation of nonpreferred 
agents, the policy had no discernable impact on rates of switching 
therapy among patients currently on treatment); Farley, et al., 
``Retrospective Assessment of Medicaid Step-Therapy Prior Authorization 
Policy for Atypical Antipsychotic Medications,'' 30 Clinical 
Therapeutics 1524 (April 2008) (showing, for a group of Medicaid 
patients with schizophrenia who were subject to a prior authorization 
policy for atypical antipsychotic medications, significant increases in 
per member per month outpatient expenditures far exceeded the 
associated savings in atypical antipsychotic expenditures).
---------------------------------------------------------------------------
                        medicaid ``best price''
    Question. In the Trump administration's Blueprint, they suggested 
that because drug manufactures have to give Medicaid the ``best price'' 
on drugs, there is no incentive to offer deeper discounts to other 
payers--both government and commercial--than what is already offered 
under the Medicaid Drug Rebate Program.

    Does the Medicaid ``best price'' requirement encourage 
manufacturers to increase initial prices?

    Answer. Medicaid Best Price is not a factor in setting our launch 
prices.

    Question. What, if any, changes would you suggest we make to the 
program?

    Answer. Pfizer encourages HHS to consider how to address the 
challenges that Medicaid Best Price poses for value-based agreement 
(VBAs). Specifically, we recommend that:

          To allow for innovative approaches and risk sharing, a poor 
        outcome should not set a new price for Medicaid. This would 
        allow manufacturers to share more risk with commercial health 
        plans.

          Approaches to reporting VBAs should be as simple as 
        possible. This would help avoid creating operational challenges 
        for companies that may prevent development of innovative 
        approaches.

          Manufacturers should continue to have flexibility to make 
        reasonable assumptions in their price reporting, so that 
        reporting approaches can evolve to reflect changes in the 
        dynamic market and contracting environment.
                        outcomes-based contracts
    Question. In almost all of your testimonies, you highlight your 
support of outcomes-based contracts and how we need to be shifting our 
system toward that approach.

    How will these contracts lower drug costs for patients in both the 
near term and long-term?

    Answer. Value-based agreements (VBA) provide a framework for paying 
for medicines based on their value to patients and the overall health-
care system. There are many different types of VBAs including those 
based on clinical and/or financial performance metrics for a product. 
Based on the outcomes achieved, payers use this information to inform 
how they cover products. Products that perform better should be covered 
in a more favorable manner which often includes lower out-of-pockets 
costs for patients which is a benefit to patients in the near term. In 
the long term, patients can also benefit from other savings either 
directly, (e.g., reducing spending on other medications, lowering 
medical costs from reduced hospitalizations, doctor's visits, etc.), or 
indirectly through lower premiums based on reductions in total cost of 
care.

    Question. How will they lower overall health-care costs for our 
Federal programs?

    Answer. VBAs can be implemented in Federal programs so that the 
benefits described above can accrue to the Federal programs.

    Question. What have the preliminary results looked like so far?

    Answer. VBAs are in the very early stages of development in the 
United States. Many payers and manufacturers have tested different 
concepts but to date, VBAs have not achieved scale. There are multiple 
reasons why VBAs represent a small fraction of manufacturer/payer 
contracts (e.g., access to data, difficult and costly to administer, 
etc.). There are certain aspects of the current U.S. regulatory 
landscape that are perceived by many as not only complicating VBA 
implementation but in some cases limiting their rapid uptake. 
Stakeholders have frequently identified two key regulatory hurdles as 
limiting the expanded adoption of VBAs: (i) the Anti-Kickback Statute 
and (ii) the Medicaid Best Price calculation requirement. While these 
regulations serve important roles within the current volume-based 
reimbursement system they do not contemplate innovative value-based 
arrangements which has resulted in a lack of clarity on how to account 
for these under the current regulatory framework. Ultimately, an 
expansion of VBAs will require reforms to existing regulations that 
enable more flexibility in designing VBAs.
                       transparency/point of sale
    Question. In almost all of your testimonies, you express your 
support for the Trump administration's proposal to allow manufacturers 
to provide PBMs up-front discounts that are passed onto patients at the 
point of sale.

    Do you feel like this proposal will make the transactions within 
the drug supply chain more transparent?

    Answer. Pfizer acknowledges that providing discounts pursuant to 
the safe harbor for point-of-sale price discounts will enhance 
transparency of net pricing strategies and potentially drive downward 
pressure on net prices. Nonetheless, Pfizer believes that the proposed 
safe harbors are good for patients and lay the groundwork for the 
systemic change needed to create a simpler, more cost effective, and 
more transparent U.S. health-care system, and we are fully committed to 
operating in this new system. We are concerned, however, that plans and 
PBMs could impose new formulary restrictions and utilization barriers 
to make up for lost rebates that undermine the spirit of the rule and 
create new access challenges to patients. For patients to receive the 
benefits of the rule, we urge policymakers to ensure that no new access 
barriers are created as a way to compensate for lost rebate.

    Question. If so, would this transparency bring down drug costs--
overall and for specialty drugs?

    Answer. Only through such transparency can Pfizer and other 
industry players ensure that discounts and other price reductions 
directly benefit the patient, which is a critical factor driving 
Pfizer's support for the Proposed Rule.
         the relationship between wholesalers and manufacturers
    Question. When talking about the pharmaceutical supply chain, a lot 
of focus has been placed on the Pharmacy Benefit Manager. But there's 
another side of the equation that I'd like to ask about: how do 
wholesalers negotiate pricing with manufacturers?

    Answer. Wholesalers pay list price for our products. They may 
receive prompt pay discounts, which would reduce their net price. 
Wholesalers also can earn bona fide service fees based on performing 
services that are important to pharmaceutical manufacturers.

    Question. What impact does this have on drug costs?

    Answer. These discounts and fees are relatively consistent across 
products and do not significantly impact drug costs.

    Question. What incentives or disincentives do they have to contain 
price increases?

    Answer. As a result of the competitive nature of their business, 
wholesalers do have an incentive to contain price increases.

                                 ______
                                 
                 Questions Submitted by Hon. Ron Wyden
                          proposed rebate rule
    Question. As has been done in many other settings, drug 
manufacturers said during the hearing that one reason list prices for 
drugs are high is that pharmaceutical benefit managers (PBMs) demand 
larger and larger rebates in order for the drug to receive favorable 
placement on a formulary. You and your colleagues who testified during 
the hearing stated if the administration's proposal on changes to the 
anti-kickback safe harbor for pharmaceutical rebates took effect, your 
company would likely lower list price.

    Like many Oregonians, I am skeptical drug manufacturers would 
voluntarily lower their prices. Therefore, would you support 
legislation that would (1) make similar changes the administration has 
put forward related to Part D and Medicaid managed care, (2) change the 
rebate system in a similar way to the proposal for the commercial 
market, and (3) require drug makers to lower the list price of their 
drugs equal to the amount of rebates provided today?

    Answer. Pfizer would support legislation that reforms the current 
system of rebating to one in which payers are required to use 
manufacturer provided discounts to ensure that the patient gets the 
benefit of the discount at the point of sale. We support this reform 
across all segments of the market where private sector negotiations 
result in lower net prices including Medicare Part D, Medicaid managed 
care and the commercial markets.

    We realize that the transition away from rebates toward a point-of-
sale discount model will result in a lowering of our net prices. 
Despite this potential negative financial impact, we support efforts to 
eliminate rebates because we believe the new model will be good for 
patients.

    As currently written, the proposed rule only applies to the 
Medicare and Medicaid managed care segments of the market. It will be 
important to have any rebate reform apply to both government programs 
and the commercial market as that will also lead to a lowering of list 
prices as well. A bifurcated market will make it more challenging for 
manufacturers to reduce list price since the commercial market covers 
more than 50 percent of Americans with insurance and represents over 
half of the business for most manufacturers.

    If the proposed rule is modified to apply to all market segments, 
we would evaluate the best options to arrive at a net price that 
ensures patients have access to our medicines. Decisions would be made 
on a product by product basis given that each therapeutic class has its 
own set of competitive and access dynamics. To ensure these benefits 
reach patients, it will be important for policymakers to ensure that 
plans do not create new barriers or restrictions that hinder patient 
access and undermine the spirit of the rule.
                      medicaid drug rebate program
    Question. The Medicaid Drug Rebate Program (MDRP) requires 
manufacturers to provide a basic rebate and an additional inflationary 
rebate for both brand and generic drugs. The inflationary rebate is an 
increasingly substantial part of total rebates due in large part to 
large increases in drug prices that exceed inflation. Under current 
law, this inflationary rebate is capped at 100 percent of Average 
Manufacturer Price (AMP). This is the case even when manufacturers 
continue to raise their prices well above inflation.

    Please provide a list of all of your pharmaceutical products that 
have reached the Medicaid AMP rebate cap in any of the 20 quarters from 
January 1, 2014 through December 31, 2018.

    For each drug listed in response to question 1, please also provide 
a list of which quarters and years each drug hit the cap.

    Answer. Given the highly confidential nature of the information 
requested, we would need to discuss the scope of this request with your 
staff.
                medicaid drug rebate program compliance
    Question. I am concerned about recent reports and legal settlements 
surrounding drug manufacturers' failure to comply fully with the 
requirements of the MDRP. For example, an analysis by the U.S. 
Department of Health and Human Services Office of Inspector General 
found that between 2012 and 2016 taxpayers may have overpaid by as much 
as $1.3 billion for 10 potentially misclassified drugs. That is why I 
introduced the Right Rebate Act with Chairman Grassley to prevent drug 
manufacturers from manipulating Medicaid to increase their profits. 
However, I continued to be concerned about oversight and manufacturer 
compliance with the requirements of the Medicaid Drug Rebate Program. 
Accordingly, please describe the following: your company's current 
compliance plan and procedures used to ensure compliance with the 
requirements of the Medicaid Drug Rebate Program including internal 
audits or other checks you use to identify compliance vulnerabilities; 
any past or ongoing issues of non-compliance; any corrective actions 
taken to address identified problems or issues of non-compliance with 
the MDRP and how such steps were communicated to the Centers for 
Medicare and Medicaid Services; and any steps taken to improve 
compliance and ensure that all Medicaid drug rebates owed to the 
Federal Government and the States are paid in full.

    Answer. It is Pfizer's policy to comply with all legislation, 
regulations, provisions, requirements, terms and conditions of the 
MDRP.

    In order for its outpatient drugs to be covered by the Medicaid 
program, a manufacturer must enter into a national rebate agreement 
with the Secretary of HHS. This agreement generally requires 
manufacturers to offer Medicaid agencies the mandated discounts for 
covered prescription drugs. Pfizer is responsible for calculating and 
reporting to the Federal Government on a monthly and quarterly basis 
various metrics for each of Pfizer's products and, ultimately, for 
paying corresponding rebates based on Medicaid recipients' purchases of 
the company's covered drugs. In return for these rebates, State 
Medicaid agencies must pay for all of the drug company's covered drugs 
(with certain limited exceptions). If the price of the manufacturer's 
drug rises faster than the inflation rate, States may require an 
additional rebate. Pfizer and/or its predecessor entities have signed a 
Rebate Agreement with HHS for all Pfizer labeler codes and Pfizer 
remains vigilant of its obligations under the Medicaid Drug Rebate 
Program.

    The Company has robust policies and procedures to ensure compliance 
with government price calculations, certification and reporting under 
MDRP including Pfizer's certification, reporting, payment obligations, 
records retention and audit obligations. The Company's policies and 
procedures are also meant to impart to Pfizer employees an 
understanding of the government pricing metrics calculated under the 
MDRP. Consistent with Pfizer's policies and procedures and available 
CMS guidance, if Pfizer becomes aware of any instances of non-
compliance with the MDRP, Pfizer reports and/or communicates with CMS. 
Based on our current information and belief, Pfizer complies with CMS 
regulations and interacts with CMS to take corrective action as 
instructed.
                 bonus payments tied to specific drugs
    Question. I am concerned by the potential for employee financial 
incentives to encourage high launch prices and price increases for 
prescription drugs.

    Is your salary, bonus, or other compensation tied to sales or 
revenue targets of a single product your company sells? Has it ever 
been? If yes, please state the product or products to which your 
salary, bonus or other compensation was tied.

    Answer. No. Dr. Bourla's salary, bonus, or other compensation is 
not nor has ever been tied to the sales or revenue targets of a single 
product.

    Question. Is your salary, bonus, or other compensation tied to 
either revenue or net income of the company as a whole? Has it ever 
been? If yes, please explain what assumptions about price increases are 
used when the compensation committee sets revenue or net income goals. 
Does the compensation committee provide any guidance to executives in 
regards to the amount of revenue that the company will generate from 
price increases versus volume growth?

    Answer. Dr. Bourla, along with over approximately 48,000 other 
colleagues, participates in Pfizer's annual bonus plan, Pfizer's Global 
Performance Plan (GPP), which is funded annually based on Pfizer's 
performance measured against three financial metrics: revenue, adjusted 
earnings per share and cash flow from operations and has been since 
2008.

    Therefore, any annual bonuses through Pfizer's GPP, determined by 
the Compensation Committee of the Board of Directors and ratified by 
the independent members of the Board, is in part based on company 
revenue and net income as adjusted earnings per share is derived from 
net income. In determining Dr. Bourla's bonus, the Compensation 
Committee also takes into account other factors such as his individual 
performance against his annual performance objectives and overall 
company performance (e.g., pipeline). Neither Dr. Bourla's salary nor 
other compensation is tied to revenue or net income of the company as a 
whole.

    In setting the corporate financial goals for compensation purposes, 
the Compensation Committee uses the company's annual budget as the 
starting point and it is adjusted accordingly based on the final 
business plan discussion which accounts for various factors, including 
access, rebates, losses of exclusivity and expected price adjustments.

    The Compensation Committee does not provide any guidance with 
regard to the amount of revenue that the company will generate from 
price increases versus volume growth.
                               net prices
    Question. In your testimony, you stated, ``In 2018, the average net 
price of Pfizer's medicines in the United States declined 1 percent.'' 
Please describe how the company's year-over-year aggregate net price is 
calculated.

    Answer. The Net Sales Price impact versus the Prior Year reflects 
the year-over-year change in average net selling price (calculated as 
net sales / units) multiplied by the current year's units. This 
calculation is performed at a product NDC level, and then aggregated up 
to the product and then the total business level.

    The company's aggregate year-over-year impact of price on growth is 
the summation of the sales price impact versus prior year from all 
products in dollars, divided by the prior year's total net revenues. In 
2018, the year-over-year impact on price on growth for the U.S. 
pharmaceutical business was negative 1 percent.

    Question. How many products are included in the calculation of the 
average net price change? What was the median net price change?

    Answer. For 2018, there are a total of 399 products included in the 
U.S. portfolio; median net price impact on growth is negative 4 
percent.

    Question. Is net price weighted? If so, how? For example, in 
determining the aggregate net price does the company assign different 
weights to different products based on volume or other factors? Are 
``on patent'' and ``off patent'' drugs weighted identically? Are other 
statistical weights used or are all products treated equally?

    Answer. Aggregate change in net price is weighted based on product 
volume (units) and mix. All products--both ``on patent'' and ``off 
patent''--are treated identically.

    Question. Does the figure that you provided during your testimony 
account for U.S. prices, international prices, or both? Generally 
speaking, when your company reports net price changes, does it 
differentiate between U.S. and international prices?

    Answer. The figure of negative 1 percent price impact on growth 
provided during the testimony is for the United States. Generally 
speaking, when we respond to inquiries on the impact of price on 
growth, we have responded on a global basis, a U.S. only basis, or 
both, dictated by how the inquiry is posed.

    Question. Please list the five drugs your company sold in the U.S. 
that had the greatest year-over-year net price increase in 2018, noting 
the increase for each drug by dollar figure and percentage.

    Answer. The following products had the greatest positive impact of 
sales price on growth in the United States in 2018: Prevnar, Lyrica, 
Chantix, Pristiq, Relpax.

    Question. Please list the five drugs your company sold in the U.S. 
that had the lowest year-over-year net price increase (and/or the 
greatest decrease) in 2018, noting the increase (or decrease) for each 
drug by dollar figure and percentage.

    Answer. The following products had the greatest negative impact of 
sales price on growth in the United States in 2018: Xeljanz, Viagra, 
Inflectra, Ibrance, Celebrex.

    Question. For 2018, what was the average net price change in the 
U.S. market for (1) drugs with no competition, (2) drugs with only 
branded competition, and (3) drugs with generic competition?

    Answer. The 2018 impact of price on growth from branded products in 
the United States was 2 percent. 2018 impact of price on growth from 
remainder of portfolio (excluding Branded Products) in the United 
States was negative 5 percent.

    Question.Pfizer has lost exclusivity for several products in recent 
years, including Viagra, Zyvox, Relpax, Tygacil, and Pristiq. For each 
of these products, please provide the percentage and dollar change in 
the average net price from (1) the last full year in which Pfizer 
maintained product exclusivity to the (2) first full year in which 
generic competition was present in the market.

    Answer. Pfizer has lost exclusivity on several products in recent 
years, including: 2014: Detrol, Rapamune, Celebrex; 2015: Zyvox; 2016: 
Relpax, Tygacil; and 2017: Viagra, Pristiq.

    In all but one case, the net price impact of the branded products 
listed above was negative the year after exclusivity was lost, 
reflecting market dynamics and the competitive environment.

                                 ______
                                 
              Questions Submitted by Hon. Robert Menendez
    Question. During the hearing, when I asked whether your company 
engaged in tactics to delay generic production of your products, you 
answered ``no''. However, Pfizer appears on the FDA's list of companies 
who have access complaints against them. Can you explain the 
discrepancy between your answer and the FDA list? The FDA list can be 
found here: https://www.fda.gov/Drugs/DevelopmentApproval
Process/HowDrugsareDevelopedandApproved/ApprovalApplications/
Abbreviated
NewDrugApplicationANDAGenerics/ucm607738.htm.

    Answer. As a patient-focused company and leading manufacturer of 
innovative, generic, and biosimilar medicines, Pfizer supports 
innovation and a strong, competitive marketplace. Consistent with these 
values, Pfizer does not block generic manufacturers from purchasing our 
products, and it has never been our policy to do so. Generic 
manufacturers are treated the same as any other customer seeking to 
purchase our products. Pfizer is not aware of any current, unfulfilled 
requests from a generic manufacturer to purchase a Pfizer product.

    Generic manufacturers seeking to purchase Pfizer products should 
request the product from Pfizer's authorized distributors or, if the 
product is not available at a distributor, from Pfizer directly, the 
same as any other Pfizer customers. Pfizer's website includes a list of 
our authorized distributors, from which customers (including generic 
companies) may purchase most Pfizer products (see https://www.
pfizer.com/products/medicine-distributors). For products that are not 
available via our authorized distributors and that are not in extreme 
drug shortage or unavailable due to a recall, customers can contact 
Pfizer's Customer Service center at 1-800-TRY-FIRST (1-800-879-3477) to 
purchase product directly from Pfizer. The telephone number for 
Pfizer's Customer Service center is also included on our website at 
https://www.pfizer.com/contact. Pfizer makes its products available for 
sale to appropriately licensed entities at Pfizer's listed price and on 
Pfizer's standard terms of sale. We do not have any agreements with 
authorized distributors that block the sale of Pfizer's products to 
generic manufacturers.

    Regarding the FDA List (the List), while Pfizer supports FDA's (the 
agency) goal of providing transparency, Pfizer is concerned that the 
List lacks certain key information and context and, as currently 
presented, may create the misleading impression that all products on 
the List are the result of bad faith attempts to block generic 
manufacturer access to samples. The appearance of a product on the FDA 
List means only that a generic manufacturer informed the agency at some 
point in time that it was having difficulty purchasing the listed 
product. FDA's own disclaimer states that the agency has not 
independently investigated or confirmed whether a generic manufacturer 
actually made a request to purchase product, and to whom.\8\ The FDA 
List also lacks several important pieces of information that would 
enable a New Drug Application (NDA) holder to investigate its 
appearance on the List. The List does not include: (1) which generic 
manufacturer made the request; (2) when and to whom the generic 
manufacturer made the request (e.g., to a wholesaler, directly to the 
NDA holder); (3) whether the generic manufacturer that made the inquiry 
was thereafter able to obtain product; and (4) any reason(s) why a 
generic manufacturer may not have been able to obtain product (e.g., a 
recall). Finally, Pfizer notes that FDA does not currently inform an 
NDA holder in real time when a generic manufacturer notifies the agency 
that it is having difficulty obtaining product. Had the agency informed 
Pfizer at the time it received the inquiries noted on the FDA List, 
Pfizer could have then undertaken its own efforts to resolve the issue. 
Pfizer communicated its concerns about the FDA List to the agency in 
May 2018. For your information we have included Pfizer's letter to FDA 
on this topic and the agency's response (see Exhibits 1 and 2 in the 
Appendix).
---------------------------------------------------------------------------
    \8\ (https://www.fda.gov/Drugs/DevelopmentApprovalProcess/
HowDrugsareDevelopedandAp
proved/ApprovalApplications/AbbreviatedNewDrugApplicationANDAGenerics/
ucm607738.htm).

    There are three new drug applications owned by Pfizer on the FDA 
List: Embeda (NDA 022321), Tikosyn (NDA 020931) and Hemabate (NDA 
017989). Embeda offers a good example of the List's shortcomings. 
Pfizer acquired King Pharmaceuticals (the previous NDA holder of 
Embeda) in March 2011, and two weeks later determined that Embeda 
needed to be recalled from the U.S. market due to stability issues. 
After diligently addressing the issues that led to the recall, Pfizer 
relaunched Embeda to the U.S. market in January 2015, and it is 
available for purchase via Pfizer's authorized distributors. However, 
as a consequence of the recall, Embeda was not available in the U.S. 
market for almost 4 years which may explain why a generic manufacturer 
had a problem obtaining it during those years. The FDA List does not 
specify when the generic manufacturer's inquiry regarding Embeda was 
made nor does the FDA List indicate that several generic applications 
for Embeda had been submitted to FDA in 2010 (which means that before 
the recall, several generic manufacturers were successfully able to 
purchase Embeda, conduct the necessary testing, and file Abbreviated 
New Drug Applications (ANDAs)). Pfizer has not identified any recent 
inquiries from generic manufacturers seeking to purchase Embeda that 
---------------------------------------------------------------------------
have not been fulfilled.

    The circumstances around Tikosyn also illustrate the List's 
shortcomings. Pfizer was able to identify a single inquiry made by a 
generic manufacturer directly to Pfizer to purchase Tikosyn in 2014. At 
that time, Tikosyn was subject to an FDA imposed Risk Evaluation and 
Mitigation Strategies (REMS) with Elements to Assure Safe Use 
(``ETASU'') that restricted distribution, so Pfizer responded by asking 
the manufacturer to obtain written confirmation from the FDA that 
Pfizer's provision of the product to the generic manufacturer would not 
be considered a violation of its REMS. The generic manufacturer did not 
contact Pfizer further, and Pfizer never received any written 
correspondence from the agency. FDA subsequently removed the REMS for 
Tikosyn in 2016, and multiple generic versions of Tikosyn are now 
approved, the first generic approval occurring in June 2016. This 
context is not reflected in FDA's List.

    Finally, with respect to Hemabate, this product was previously 
subject to certain restrictions on distribution (i.e., it was sold only 
to customers with medical and surgical intensive care centers) to 
ensure its safe and appropriate use. This distribution approach was 
established by the previous NDA holder (Pharmacia) and it continued 
following Pfizer's acquisition of Pharmacia in 2003. Pfizer 
discontinued this approach in early 2018 after determining that it was 
no longer necessary, and this product is now available through our 
authorized distributors. During the time when Hemabate was under 
restricted distribution, it was not available at Pfizer's authorized 
distributors, but had a generic manufacturer approached Pfizer's 
Customer Service center directly, we would have been able to address 
the inquiry. Pfizer's Customer Service was not able to identify any 
specific requests from a generic manufacturer to purchase Hemabate that 
have not been fulfilled.

    We hope that this information explains the apparent discrepancy 
between Mr. Bourla's testimony and the appearance of these Pfizer 
products on the FDA List, and demonstrates Pfizer's diligence on these 
issues and commitment to a competitive marketplace.

    Question. When new products enter the market, do drug companies set 
high initial rebates and then provide deep rebates in order to gain 
access to insurance plan's formularies?

    Answer. Launch pricing is driven by a multitude of factors, the 
most important being the medicine's impact on patients and their 
health. We also may consider other factors like the medicine's 
potential to reduce other health-care costs, such as hospital stays; 
the availability of other treatments and generic options; affordability 
for patients, insurers and governments; and investments to maintain the 
quality, safety, delivery, and reliability of our medicines.

    Given the consolidation that has taken place in the U.S. market, 
the vast majority of retail prescriptions are managed by a few large 
PBMs. Pharmaceutical manufacturers must successfully negotiate with 
these PBMs to gain access to their formularies or risk having their 
products disadvantaged or even excluded from coverage.

    The system has evolved in a manner where rebates play a significant 
role in how the PBM business is transacted and in the decisions 
regarding product placement on formularies. PBMs often win or lose 
business on the basis of rebate guarantees and are therefore 
incentivized to favor products with high list prices and deep rebates 
assuming comparable safety and efficacy. Because the PBMs have enormous 
leverage and depend on rebates to attract and retain clients, many 
manufacturers will enter the market with higher list prices and deeper 
rebates in order to ensure patients have access to their medicines.

    Question. If CMS finalizes the rebate rule, do you anticipate 
future products entering the market with significantly lower initial 
list prices?

    Answer. Launch pricing will be driven by product value and 
competitive intensity of the specific therapeutic category. 
Importantly, if finalized, the rule could result in lower out-of-pocket 
patient costs at the pharmacy counter and help address the perverse 
incentives in the system that have been contributing to higher list 
prices for medicines.

                                 ______
                                 
              Questions Submitted by Hon. Thomas R. Carper
    Question. What are your recommendations for lowering prices for the 
40 percent of drugs that do not offer rebates in Medicare Part D? In 
the health insurance plans that you offer your employees, do you ask 
your insurers to pass through the full manufacturer rebates to the 
beneficiaries?

    Answer. It is unclear if the 40 percent of drugs that do not offer 
rebates in Medicare Part D are brand medicines or generics. However, 
Pfizer pledges to bring more affordable treatment options to the 
market. Our mid-to late-stage pipeline contains five biosimilar 
candidates expected to launch in the next 2 to 3 years. Ninety percent 
of medicines Americans take are generics, and competition from these 
drugs keeps prices low in most cases. We need to bring similar 
competition to the biologics market, where some of the most expensive 
drugs exist. The market today has already seen demonstrated savings as 
high as 40 percent relative to the branded product. With more 
competition, we hope even further savings can be realized.

    Pfizer's plan design is generous and corresponding employee cost 
sharing for prescription drugs is already very limited--in fact, for 
many products, Pfizer employees experience no cost sharing at all. 
Given this, the terms of contract with our PBM for our employee 
benefits does not include a requirement to pass on rebates to Pfizer 
employees at the point of sale.

    Question. The systems for pricing and distributing drugs are opaque 
and difficult to understand. What are your recommendations for 
increasing transparency in how your companies set the list prices for 
drugs, and for improving transparency in the supply chain for 
prescription drugs? Would you support Federal standards for 
transparency in setting the list prices for drugs?

    Answer. Pfizer supports system-wide price transparency that is 
thoughtful, purpose-driven, and that can result in improved patient 
care, an enhanced understanding of the comparative value of all medical 
services, and a more patient-centered use of health-care resources.

    We would be interested in exploring with the committee ways to 
ensure transparency across the health care system, including hospitals, 
plans, PBMs, etc., so that we can make informed judgments about the 
root of cost inflators in the system. We are also committed to ensuring 
that patients, health-care professionals and payers understand our 
commitment to pricing our medicines responsibly.

    Regarding a Federal transparency standard, we believe that an 
appropriately crafted, balanced piece of Federal legislation that 
applies to all stakeholders in the health care system and preempts 
future State laws could be beneficial for patients. However, Pfizer 
believes that mandating disclosure of research and development, 
manufacturing, or marketing costs to assess the value of medicines is 
inconsistent with purpose-driven transparency.

    Question. In nearly every sector of the health-care industry, 
Medicare, Medicaid, employers, and insurers are moving away from fee-
for-service payments to reimbursements based on value and performance. 
Prescription drugs and medical devices were the glaring exceptions to 
this trend until recently. How many of your drugs are included in 
value-based contracts and how many patients are benefiting from them?

    Answer. Patient outcomes should determine our reimbursement and 
Pfizer pledges that we will aggressively pursue value-based 
arrangements. We should not be rewarded for treatments that do not 
work.

    Currently, Pfizer has value-based contracts for twelve drugs in our 
portfolio.

    The agreements are in place with commercial and Medicare payers 
with millions of covered lives. In addition, Pfizer has a multi-product 
innovative agreement that has been offered to the majority of States 
for the Medicaid program, but currently only a small number of States 
compromising less than five million lives have taken or are actively 
considering the offer.

    Question. How do these value-based contracts work to lower drug 
prices for both patients and taxpayers?

    Answer. Value-based agreements (VBA) provide a framework for 
manufacturers to be compensated based on a product's value to patients 
and the overall health-care system. There are many different types of 
VBAs but the optimal structure of a VBA includes clinical and/or 
financial performance metrics for a product. Based on the outcomes 
achieved, payers use this information to inform how they cover 
products. Products that perform better should be covered in a more 
favorable manner which often includes lower out-of-pockets costs for 
patients which is a benefit to patients in the near term. In the long 
term, patients can also benefit from other savings either directly, 
(e.g., reducing spending on other medications, lowering medical costs 
from reduced hospitalizations, doctor's visits, etc.), or indirectly 
through lower premiums based on reductions in total cost of care.

    VBAs can be implemented in Federal and State programs so that the 
benefits described above can accrue to the Federal programs thereby 
benefitting taxpayers.

    Question. Last year, Senator Portman and I did an investigation on 
the pricing of an opioid overdose reversal drug called EVZIO, 
manufactured by Kaleo. Kaleo increased the price of EVZIO from $575 in 
2014 to $4,100 in 2017. We found that the best price Medicare was able 
to get for EVZIO, about $4,000, was much higher than the price other 
Federal programs and private insurers were able to get. It seemed that 
Kaleo was able to get this higher price of $4,000 from Medicare by 
helping doctors fill out paperwork showing that the drug was medically 
necessary, even though there are cheaper alternatives on the market. As 
a result of the investigation, Kaleo announced it will bring a generic 
version of the drug to market at only $168 per pack. Are any of your 
companies providing medical necessity paperwork to doctors in order to 
get your drugs covered by Medicare?

    Answer. Consistent with industry practice, Pfizer provides a sample 
statement of medical necessity and appeals letters through our patient 
support programs for patients, their caregivers and prescribing 
physicians to help guide these individuals in gaining access to certain 
Pfizer medicines after a physician has determined that a Pfizer product 
is right for a patient and a prescription has been written. These 
sample letters are generally PDF documents that describe the type of 
information payers require to approve access/coverage of a particular 
medication based upon the payers' formulary requirements, such as step 
therapy (therapeutic agents that must be tried first), proof of 
diagnosis or other common utilization management techniques that payers 
determine. Pfizer does not customize these letters, and patients, 
caregivers and physicians are advised that they are responsible for the 
accuracy of the information that they submit to the payer to obtain 
coverage and/or reimbursement. Sample letters are available from 
Pfizer's third-party call centers which specialize in product access 
triage with payers, field based reimbursement specialists and Pfizer 
product websites. Pfizer sales representatives do not provide this 
information to physicians.

    Question. In 2017, the Rand Corporation estimated that biosimilar 
drugs, which are competitors to complex, biologic drugs, could save the 
United States more than $50 billion over the next decade. Some of you 
have also argued that increasing the use of biosimilar drugs would help 
lower drugs costs for consumers and taxpayers. What is delaying the 
uptake of biosimilar drugs in the United States? What policies do you 
recommend to increase the development of biosimilar drugs?

    Answer. Pfizer believes that some of the adverse incentives and 
barriers to market penetration include:

        1.  The Rebate Trap: Brand-name biologic companies are using 
        maneuvers to block biosimilar competition such as higher 
        rebates and exclusionary contracts.

        2.  Misinformation: Some physician and patient-directed 
        materials created by brand companies mischaracterize 
        biosimilars, creating doubt and confusion about the safety and 
        efficacy of biosimilars. As defined by statute, an approved 
        biosimilar must be highly similar to and have no clinically 
        meaningful differences from the reference product and must have 
        the same mechanism of action (to the extent the mechanism(s) of 
        action of the reference product are known) as the reference 
        product; thus, by definition, biosimilars are safe and 
        efficacious treatments relative to the reference product and 
        must work in the same way as the reference product. Any 
        information disseminated by reference product sponsors to 
        suggest or imply otherwise should be promptly addressed by FDA.

        3.  Need for incentives: Legislative ideas to promote 
        biosimilar uptake could include a shared savings biosimilar 
        model; reduced patient cost sharing for biosimilars. More 
        detail is provided below.

    Although the biosimilars market in the United States is still 
relatively new, our experience has been that anticompetitive conduct by 
brand-name biologic manufacturers, combined with the lack of policy 
measures to support appropriate uptake of biosimilars, have contributed 
to a slow uptake. Therefore, we encourage you to consider measures to 
help incentivize the use of biosimilars, which can substantially lower 
Medicare costs with demonstrated savings to date as high as nearly 40 
percent relative to the branded biologic.

    Some key policy initiatives we believe will support the uptake of 
biosimilars in the United States are the following:

          Waiver of Part B Patient Coinsurance for Biosimilars for a 
        certain period of time:

              CMS should waive Part B patient coinsurance 
        amounts for biosimilars. Cost-sharing changes could be applied 
        at the HCPCS level. This would not change the overall payment 
        for a biosimilar; however, it would change the beneficiary's 
        payment percentage.

          CMS should pursue a CMMI model designed to increase access 
        to biosimilars, including a ``shared savings'' model whereby 
        Medicare savings associated with prescribing a biosimilar, as 
        compared to a reference biological, would be shared with 
        providers.

          CMS should maintain the current biosimilar pass-through 
        status as this provides biosimilars with a ``level playing 
        field'' with their higher priced reference biologic 
        competitors.

          CMS should create payment incentives for plans by 
        contracting with a measure developer for a biosimilar use 
        measure for the STARS program, which would correct other 
        adverse incentives for biosimilar uptake for Medicare Advantage 
        plans.

                                 ______
                                 
             Questions Submitted by Hon. Benjamin L. Cardin
    Question. The United States is one of the only countries in the 
world to allow prescription drug manufacturers to advertise directly to 
consumers through magazines, billboards, radio, and television 
commercials. While I will not argue that it is beneficial to educate 
consumers about an unfamiliar disease and encourage them to seek 
medical help, most commercials from all of your companies recommend 
asking about a specific brand name drug, not a medical condition. 
Furthermore, even if your advertisements follow all FDA rules and list 
medication side effects, they also almost always list these while a 
smiling, apparently healthy person is walking on a beach.

    Researchers say that this type of imagery, combined with viewing 
hours of drug commercials each month, leads consumers to underestimate 
the risks associated with medications. For the past decade, studies 
have shown that aggressive direct-to-consumer advertising is associated 
with rising drug prices and an increase in inappropriate drug 
prescriptions.

    Since researchers have concluded that consumers are 
misunderstanding the benefits and risks described in your ads, what 
further policies could help you and your colleagues ensure that you are 
educating patients in a clear manner?

    Answer. Pfizer wants patients to have access to our drugs and part 
of this is making sure patients have the information they need. Pfizer 
believes that direct-to-
consumer (DTC) advertising should be, first and foremost, a tool 
through which we can provide patients with useful information to inform 
them about their medical conditions, and the potential benefits and 
risks of available treatment options so they can have a discussion with 
their doctors and take an active role in managing their health.

    The Office of Prescription Drug Promotion at the FDA, which has 
responsibility for reviewing prescription drug advertising and 
promotional labeling to ensure that the information contained in them 
is not false or misleading, studies advertising so that regulations are 
grounded in evidence on how best to ensure ads are accurate, balanced 
and not misleading. The FDA's website describes in detail the many ways 
that its Office of Prescription Drug Promotion ensures that DTC 
advertising is not misleading.\9\
---------------------------------------------------------------------------
    \9\ https://www.fda.gov/aboutfda/centersoffices/
officeofmedicalproductsandtobacco/cder/ucm
090142.htm.

    DTC advertising is of significant educational importance to 
patients, especially as the provision of health care becomes more 
patient-centric. Over the last 2 decades, consumer research sponsored 
by the industry and the FDA has underscored that clear, relevant 
communication allows DTC advertising, when executed thoughtfully, to 
have a positive impact on public health. For example, in 2004, a study 
by FDA found that ``DTC ads help patients have better discussions with 
their physicians and provide greater awareness of treatments. The study 
demonstrated that when a patient asked about a specific drug, 88 
percent of the time they had the condition that the drug treated. And 
80 percent of physicians believed their patients understood what 
---------------------------------------------------------------------------
condition the advertised drug treats.''

    More recently, according to a 2017 survey, conducted by Princeton 
Survey Research Associates International on behalf of PhRMA, Americans 
overwhelmingly reported that DTC advertisements help inform people 
about new treatments (88 percent), alert people to symptoms that are 
related to a medical condition they may already have (81 percent), and 
allow people to be more involved in their health care (79 percent).\10\ 
Similarly, a research survey published in 2017 with 4,481 U.S. adults 
and sponsored by a working group of pharmaceutical companies has shown 
DTC advertising conveys useful information.\11\ DTC ads raise awareness 
about medications and effectively communicate potential risks and 
benefits, but they also increase concern about potential side effects.
---------------------------------------------------------------------------
    \10\ 2017 Direct to Consumer Advertising Survey Results, presented 
by Princeton Survey Research Associates International, prepared for 
PhRMA, https://www.phrma.org/report/2017-direct-to-consumer-
advertising-survey-results.
    \11\ DIA, Therapeutic and Regulatory Science, https://
journals.sagepub.com/doi/abs/10.1177/2168479017708226iii, https://
www.fda.gov/AboutFDA/CentersOffices/OfficeofMedicalProducts
andTobacco/CDER/ucm090276.htm#Completed.

    Pfizer believes that PhRMA, individual companies, academics and FDA 
should continue to study DTC advertising to ensure that pharmaceutical 
consumer communications are achieving their intended goals to educate, 
inform information-seeking consumers and facilitate better discussions 
with health-care professionals.
           pharmaceutical companies continue to raise prices
    Question. As you are well aware, high prescription drug prices are 
the number one concern for Americans and their families. According to 
the Organization for Economic Cooperation and Development, the average 
American spends around $1,208 annually on prescription drugs. There 
have been several instances where brand name or even generic drugs that 
have been on the market for years continue to increase in price.

    One of the most well-known examples is Mylan's increase of the 
price of EpiPen from less than $100 in 2007 to more than $600 in 2016. 
Another example, is the ever-increasing price of insulin. Sanofi 
increased the price of a vial of Lantus from $88.20 in 2007 to $307.20 
in 2017. And those are just a small sample of price increases.

    Why don't we see price decreases for drugs that have been on the 
market for years without new formulations or added benefit?

    Answer. There are a number of reasons that the price of medicines 
can change over time. While these reasons often include more obvious 
changes such as discovery of new indications and new formulations, they 
can also include less obvious changes such as improvements in the 
manufacturing and supply chain and market-based factors.

    Pfizer has reduced the price of many of our older off-patent 
medicines in the United States, and we are committed to bringing more 
affordable treatment options to the market to induce competition, 
including generic and biosimilar medicines. Competition is the best way 
to promote affordable access to quality, safe and effective medicines; 
competition means more and better medicines, more options for patients, 
and more affordable drugs.
                             pay for delay
    Question. Pay for delay is a tactic that more and more branded drug 
manufacturers have been using to stifle competition from lower-cost 
generic manufacturers. This allows you to sidestep competition by 
offering patent settlements that pay generic companies not to bring 
lower-cost alternatives to market.

    These ``pay-for-delay'' patent settlements benefit both brand-name 
pharmaceutical companies by helping them avoid costly patent litigation 
and general manufacturers by rewarding them a hefty sum to delay 
entering the market with a cheaper drug alternative. However, these 
deals do not benefit consumers. According to an FTC study, these 
anticompetitive deals cost consumers and taxpayers $3.5 billion in 
higher drug costs every year.

    Does your company partake in pay-for-delay settlements?

    Answer. No. On the contrary, when Pfizer settles patent litigation 
with generic firms, we do so on terms that generally enable entry of 
generic competition earlier than the expiration of its patents and that 
do not involve unlawful reverse payments. Pfizer's patent settlements 
thus involve lawful compromises that appropriately resolve patent 
disputes and accelerate patient access to lower cost generics relative 
to the expiration of its patents. While Pfizer has been the target of 
plaintiff lawyer driven class action lawsuits challenging certain of 
its settlements with generic companies, we believe these lawsuits are 
without merit and are vigorously asserting the pro-competitive nature 
of these settlements in court.

    Question. Why would a pharmaceutical company enter into a pay-for-
delay agreement?

    Answer. Pfizer does not enter into these types of settlements and 
cannot speculate on why others might.

    Question. Do you think these agreements stifle competition and 
prevent generic alternatives to your branded medications?

    Answer. Pfizer's patent settlements do not ``stifle competition'' 
or ``prevent generic alternatives.'' On the contrary, when Pfizer 
settles patent litigation with generic firms, it does so on terms that 
generally enable entry of generic competition earlier than the 
expiration of its patents and that do not involve unlawful reverse 
payments. Pfizer's patent settlements thus involve lawful compromises 
that accelerate patient access to lower cost generics relative to the 
expiration of its patents.
                            drug rebate rule
    Question. In January, the Department of Health and Human Services' 
(HHS) Office of Inspector General (OIG) promulgated a new regulation to 
remove regulatory safe harbor protections under the Anti-Kickback 
Statute (AKS) for rebates on prescription drugs rebates paid by 
manufactures to PBMs under Medicare Part D and for Medicaid managed 
care organizations (MCOs). The OIG proposal attempts to ban most 
rebates by eliminating their regulatory protections.

    The rule is predicted to increase net drug costs in its early 
years. The CMS actuaries estimate it would cost $196 billion over 10 
years. Despite this high price tag, the beneficiary benefits are 
limited. The proposed rule notes that under the CMS Actuary's analysis, 
the majority of beneficiaries would see an increase in their total out-
of-pocket payments and premium costs; reductions in total cost sharing 
will exceed total premium increases.

    I wanted to ask a question about the administration's rebate rule, 
which I understand that many of the drug manufacturers, and your main 
trade association, strongly support. According to an analysis of the 
rule by the Office of Actuaries at CMS, drug manufacturers are likely 
to initially retain 15 percent of the current rebates as higher net 
drug prices.

    Given that estimate, can you provide the committee with any 
assurances that prices will not increase under this proposed rule?

    Answer. If finalized, the rule could result in lower out-of-pocket 
patient costs at the pharmacy counter and help address the perverse 
incentives in the system that have been contributing to higher list 
prices for medicines. In 2019, Pfizer expects to pay billions of 
dollars in rebates to ensure patients with pharmacy benefits coverage 
in Medicare Part D and patients in commercial plans have access to our 
medicines. If the proposed rule to share rebates with consumers at the 
point of sale is finalized, we estimate that seniors taking Pfizer 
medicines could save $270 on average per year, and up to $574 per year 
for certain Pfizer medicines, through lower cost sharing.

    Importantly, we believe any reform should apply to all market 
segments as this could also lead to further reduction in list prices. A 
bifurcated market in which we eliminate rebates in government programs 
but maintain rebates for commercial plans will make it difficult for 
manufacturers to reduce list prices because a single list price applies 
to all markets.

                                 ______
                                 
               Questions Submitted by Hon. Sherrod Brown
    Question. According to an article recently published in the Journal 
of the American Medical Association, medical marketers spent nearly $30 
billion dollars in 2016, up from $17 billion in 1997. Direct-to-
Consumer (DTC) advertising had the biggest percentage increase: from 
$2.1 billion, or 11.9 percent of all medical marketing, in 1997 to $9.6 
billion, or 32 percent of total spending, in 2016.

    Can each of you please provide what your ratio of spending on sales 
and marketing to research and development is today?

    Answer. In order to fulfill Pfizer's mission to create breakthrough 
medicines that change patients' lives, we invest in several areas to 
ensure an innovative pipeline, top-quality manufacturing, and education 
of patients and physicians to ensure they have the information they 
need to make knowledgeable decisions about patient care.

    In 2018, Pfizer spent approximately $6.9 billion on direct sales 
and marketing and approximately $8 billion on research and development 
globally.
                        biosimilars/rebate traps
    Question. In many of your testimonies, you mention that encouraging 
the development of generics and biosimilars will help bring down the 
cost of drugs. However, while 17 biosimilars are now approved in the 
US, only 7 are actually on the market and available to patients. There 
are growing concerns about rebate traps, which are ways of gaming the 
system to ensure a biosimilar is not able to enter the market.

    Dr. Bourla, in your testimony, you said: ``Adverse incentives that 
favor higher cost originator biologics are keeping biosimilars from 
reaching patients. In many cases, payers decline to include lower cost 
biosimilars or generics in their formularies because they would risk 
losing the rebates they can get by covering higher cost medicines.'' 
Your company has filed lawsuits challenging rebate traps as antitrust 
violations. What do you think should be done about these rebate 
practices?

    Answer. Anticompetitive conduct should be stopped through 
government enforcement of the antitrust laws and in the courts. Brand-
name biologic companies should not be permitted to abuse the rebate 
system to effectively block lower-cost biosimilars from coverage

    For more details, see Pfizer's Exhibit 4 attached.
                             price-gouging
    Question. Sanofi, as I understand it, has made a pledge to the 
public to limit its price increases to the national health expenditures 
growth projection.

    Would your company commit to a cap on annual price increases as 
part of your PhRMA membership criteria?

    Answer. We are unable to answer this question as it requires 
analysis under the antitrust laws.

    Question. What policies would you propose to help ensure lower 
launch prices for new drugs?

    Answer. At Pfizer, we are committed to our purpose: breakthroughs 
that change patients' lives. Pfizer's more than 90,000 colleagues 
around the world come to work every day focused not only on creating 
breakthrough medicines, but also on making sure those medicines get 
into the hands of the patients who need them.

    The launch prices for our medicines reflect the value that they 
bring to patients and society. The relationship between the price of a 
medicine and a patient's out-of-pocket cost is not always clear. Out-
of-pocket costs continue to rise due to insurance designs that place a 
disproportionate burden on consumers who use medicines than other 
interventions. Consumers on average pay 15 percent of medicine costs 
but only 2 percent of hospitalization and other health-care costs. We 
encourage Congress to continue its efforts to understand the complexity 
of the pricing and reimbursement system in the United States, and to 
identify ways in which patient out-of-pocket expenditures can be 
reduced.
                              transparency
    Question. In many of your testimonies, you mentioned that the 
current system of pharmacy benefit manager (PBM) back-end rebates do 
not rarely results in a scenario where the PBM passes on savings to 
consumers at the point of sale (POS). The administration recently 
proposed a rule to eliminate the anti-kickback statute safe harbor 
protections for these drug rebates.

    Do you agree that greater transparency should be required to 
understand how manufacturers and PBMs are negotiating prices and 
rebates to ensure that savings are passed down to beneficiaries?

    Answer. Pfizer is committed to working toward greater transparency 
along the supply chain, so patients can better understand what they are 
paying for and why. We believe pricing transparency policies should 
seek to inform consumers about the costs of health-care items and 
services across the industry and should promote a definition of value 
that considers impact to health and costs over time and across all 
industry stakeholders.

    Pfizer believes that the proposed safe harbors lay the groundwork 
for the systemic change needed to create a simpler, more cost 
effective, and more transparent U.S. health-care system, and we are 
committed to operating in this new system.

    Question. Senator Thune asked if this administration rule would 
lead you to lowering list prices. Both of you answered that you would 
be likely to lower your prices. However, if this rule were finalized 
tomorrow as proposed, would any of your companies be required to lower 
the list price of any of your drugs?

    Answer. As long as rebate reform extends to both the commercial 
market and government programs, there could be a reduction in list 
prices. The commercial market covers more than 50 percent of Americans 
with insurance, and the safe harbor will not affect it at all. However, 
in Medicare, the rebate rule will make list prices less relevant 
because the entire rebate will be converted to a point of sale discount 
so that patient out-of-pocket costs, when they are in the deductible, 
coinsurance, and coverage gap phases of the benefit, will be based off 
the lower net price. If we ensure that rebates paid out to commercial 
plans find their way to patients, the patients will see savings of 
hundreds of dollars.
                                  pbms
    Question. An Axios article from March 7, 2019 highlights the fact 
that, while ``pharmaceutical companies put a lot of the blame for high 
drug prices on pharmacy benefit managers,'' many large pharmaceutical 
companies ``rely on PBMs to manage their own health-care benefits.''

    In your role as an employer, does your company contract with a 
pharmaceutical benefit manager (PBM) to administer the prescription 
drug benefits for your employees and negotiate lower drug costs on your 
behalf?

    Answer. Yes, we contract with a PBM to administer our prescription 
drug benefits and we work with them to establish criteria for 
negotiating lower drug costs on our employees' behalf.

    Question. For those of you who do use a PBM to help manage the 
prescription drug benefit for your employees, how do you utilize the 
rebates your PBM negotiates to lower health-care costs or drug costs 
for your employee plans, and what does your company do with that 
savings? Specifically, do the savings go toward lowering premiums?

    Answer. Pfizer's medical and prescription drug coverage is generous 
in terms of what we subsidize as an employer; therefore we work to 
ensure that our employees benefit from our investment in our workforce 
and any savings in the form of affordable plan premiums and 
substantially lower cost sharing responsibilities for prescription 
drugs.

    Question. For those of you who do use a PBM to help manage the 
prescription drug benefit for your employees, does your PBM offer 
point-of-sale rebates to your employees?

    Answer. Pfizer's plan design is generous and corresponding employee 
cost sharing responsibility for prescription drugs is already very 
limited--in fact, for many products, Pfizer employees experience no 
cost sharing at all. Given this, the terms of contract with our PBM for 
our employee benefits does not include a requirement to pass on rebates 
to Pfizer employees at the point of sale.

                                 ______
                                 
             Questions Submitted by Hon. Sheldon Whitehouse
    Question. Please describe any policy changes you support that would 
result in your company lowering the list prices of its drugs.

    Answer. Pfizer would support legislation that reforms the current 
system of rebating to one in which payers are required to use 
manufacturer provided discounts to ensure that the patient gets the 
benefit of the discount at the point of sale. We support this reform 
across all segments of the market where private sector negotiations 
result in lower net prices including Medicare Part D, Medicaid managed 
care and the commercial markets. It is important to understand that 
even if rebates are prohibited, manufacturers will still negotiate 
discounts with plans consistent with safe harbors in exchange for 
formulary access, though those discounts will be reflected in lowered 
drug prices at the pharmacy counter rather than retrospective payments 
benefitting plans or their PBM instead of the beneficiaries who are 
underwriting premiums for others.

    To ensure these benefits reach patients, it will be important for 
Congress and the administration to ensure that plans do not create new 
barriers or restrictions that hinder patient access and undermine the 
spirit of the rule.

    Question. How much does your company's research and development 
portfolio rely on taxpayer-funded research conducted by the National 
Institutes of Health (NIH)?

    Answer. The biopharmaceutical industry is one of the most research-
intensive industries in the United States. In 2017, NIH had a budget of 
$39.2 billion, only a fraction of which, $3.2 billion, was dedicated to 
drug discovery. The industry invested over $90 billion in R&D--almost 
30 times more. For Pfizer alone, we invested approximately $8 billion 
in R&D last year.

    NIH's strength is its focus on important basic scientific research 
and the industry does derive important insights from basic scientific 
research conducted by NIH-funded researchers and scientists worldwide. 
There is, however, a large gap between understanding basic scientific 
principles and the discovery, development, and delivery of medicines to 
patients. For example, the initial NIH-funded basic science discovery 
of cell division and cell signaling proteins in yeast led researchers 
to identify similar proteins in humans. This early research later 
informed the thinking of Pfizer scientists and helped pave the way for 
the discovery and development of targeted cancer drugs like 
palbociclib, a new treatment for breast cancer.

    The discovery of cell division in yeast is a long way from 
discovering and developing a drug that prevents cancer tumors from 
growing. As stated above, the government plays a role in advancing 
basic science such as identifying cellular pathways underlying disease. 
However, the ability to translate knowledge about biological processes 
into a medicine or vaccine, with appropriate drug-like properties and a 
clinically meaningful benefit, remains the primary function of the 
biopharmaceutical industry. The drug discovery and development process 
involves harnessing existing knowledge of underlying disease biology to 
chart and execute a research agenda that often encompasses ten to 15 
years of discovery research, preclinical testing, clinical development 
(for dosing, safety, and efficacy) and pharmaceutical science to ensure 
the quality of the compound to be delivered. Disciplines like medicinal 
chemistry, process and formulation chemistry and formulation, drug 
metabolism, pharmacokinetics and safety sciences are practiced at a 
scale and expertise in the biopharmaceutical industry that extends well 
beyond government and academic research endeavors to deliver life-
savings therapies for patients.

    Question. How many of your company's products are based, at least 
in part, on NIH research, and how many are the result of research 
funded solely by your company?

    Answer. We have not identified readily available information in 
response to this request that is maintained in the ordinary course of 
business. We would need to discuss the scope and terms of this question 
with your staff to respond appropriately.

    Question. In each of the last 5 years, how much has your company 
spent on research and development versus the advertising and marketing 
of your products?

    Answer. In order to fulfill Pfizer's mission to create breakthrough 
medicines that change patients' lives, we invest in several areas to 
ensure an innovative pipeline, top-quality manufacturing, and education 
of patients and physicians to ensure they have the information they 
need to make knowledgeable decisions about patient care.

    Over the last 5 years, Pfizer spent approximately $34 billion on 
advertising and marketing and approximately $40 billion on R&D 
globally. Advertising and marketing expenses include advertising, 
promotion and field selling.

    Question. During the hearing, you mentioned that your company would 
be likely to lower the list prices of its drugs if the recent proposal 
by the Trump administration to change the current system of rebates was 
extended to the private market.

    If the policy was extended to the private market, how large would 
the list price reductions be relative to the size of the rebates your 
company is currently providing?

    Answer. The size of any list price reductions relative to the size 
of rebates Pfizer is currently providing would depend on all components 
of the final rule and how the point of sale discount model that 
replaces rebates will function.

    Question. How will this proposal affect how your company sets the 
list prices for new drug products?

    Answer. At Pfizer, we are committed to our purpose: breakthroughs 
that change patients' lives. Pfizer's more than 90,000 colleagues 
around the world come to work every day focused not only on creating 
breakthrough medicines, but also on making sure those medicines get 
into the hands of the patients who need them.

    Launch pricing is driven by a multitude of factors, the most 
important being the medicine's impact on patients and their health. We 
also may consider other factors like the medicine's potential to reduce 
other health-care costs, such as hospital stays; the availability of 
other treatments and generic options; affordability for patients, 
insurers and governments; and investments to maintain the quality, 
safety, delivery and reliability of our medicines.

    Question. If the proposal is finalized and not extended to the 
private market, will your company make any list price reductions? If 
so, how large would the reductions be relative to the size of the 
rebates your company is currently providing?

    Answer. Because there is no specific requirement for plans and PBMs 
to shift away from negotiating contracted rebates in the commercial 
market, it is possible that a bifurcated market, with the same perverse 
incentives and the same mechanism to drive list prices higher, will 
result. If reform does extend to the commercial marketplace, it could 
result in lowering of list prices. However, we cannot speculate on the 
amounts until we see the specifics of the rule and the changes that are 
made to the supply chain.

                                 ______
                                 
                Question Submitted by Hon. Maggie Hassan
    Question. In June of 2018, the Medicaid and CHIP Payment and Access 
Commission (MACPAC) unanimously recommended under Recommendation 1.1 in 
their annual report to Congress that Congress remove the statutory 
requirement that manufacturers blend the average manufacturer price 
(AMP) of a brand drug and its authorized generic.\12\
---------------------------------------------------------------------------
    \12\ MACPAC: ``Improving Operations of the Medicaid Drug Rebate 
Program,'' https://www.macpac.gov/wp-content/uploads/2018/06/Improving-
Operations-of-the-Medicaid-Drug-Rebate-Program.pdf.

    This requirement created an unintended loophole. Rather than use 
the price of the authorized generic, drug companies can sell its 
authorized generic to a corporate subsidiary at an artificially lower 
price, and use that lower price to bring down the AMP, which in turn 
---------------------------------------------------------------------------
lowers the rebate obligation.

    Does your company engage in this practice? Has your company ever 
engaged in this practice in the past?

    Answer. Pfizer has a number of Authorized Generics (AGs) 
arrangements, both with affiliates and non-affiliates. CMS's Medicaid 
Covered Outpatient Drugs Final Rule, 81 Fed. Reg. 5170 (Feb. 1, 2016) 
(the ``Final Rule'') included an extensive discussion of when a primary 
manufacturer should include or exclude sales of AGs to secondary 
manufacturers in its average manufacturer price (AMP). Pfizer has 
developed reasonable assumptions that it believes are consistent with 
the guidance CMS set forth in the Final Rule for purposes of 
determining when to include or exclude sales of AGs in its AMP 
calculation. Pfizer disclosed its assumptions with respect to its 
approach both in written correspondence and in an onsite meeting with 
CMS representatives. In addition, Pfizer disclosed its assumptions to 
the OIG in response to a January 2018 survey.

                                 ______
                                 
           Questions Submitted by Hon. Catherine Cortez Masto
    Question. According to public filings, in 2015 Pfizer collected 
U.S. revenues that were more than double the amount you invested in 
R&D. Is this still true--do you collect more in revenue in the U.S. 
alone than you invest in R&D?

    Answer. The biopharmaceutical industry is one of the most research-
intensive industries in the United States In 2017, NIH had a budget of 
$39.2 billion, only a fraction of which, $3.2 billion, was dedicated to 
drug discovery. The industry invested over $90 billion in R&D--almost 
30 times more. For Pfizer alone, we invested approximately $8 billion 
in R&D last year.

    Pfizer's number one priority is always the care of our patients, 
and we are proud of the investments Pfizer makes to insure we continue 
to bring new, innovative cures to patients. These responsibilities 
require investments in R&D, manufacturing and other areas to accomplish 
our mission of creating breakthrough medicines that change people's 
lives.

    In 2018, Pfizer spent approximately $20 billion on global R&D and 
manufacturing. This includes investing in state-of-the-art labs so we 
can attract the finest scientists in the world and continuing to invest 
in innovative, high-tech manufacturing to ensure the high quality of 
our products. Pfizer's revenues in the United States in 2018 totaled 
approximately $25 billion.

    Question. As a portion of your revenue, for what percentage of the 
drugs in your portfolio do you offer no rebates? Based on the drugs in 
your pipeline, do you foresee that portion growing? For those drugs is 
your list price equal to your net price?

    Answer. Approximately one third of Pfizer's revenue comes from 
products that are not Medicare Part D eligible. This product group 
includes generics, vaccines, and physician administered products. Of 
the remaining two thirds of our revenue, 92 percent comes from products 
that offer Medicare Part D or commercial rebates. The remaining 8 
percent is from products that have lost patent exclusivity, have 
generic alternatives, and offer no rebates. It is not possible to 
determine at this time whether that portion will increase because 
rebating on future products will be based on numerous factors, 
including product value and the competitive intensity of the 
therapeutic area. For products that do not rebate, there are additional 
deductions from sales such as prompt payment fees and distribution 
service fees resulting in the net price being lower than list price.

    Question. Do you invest more in R&D than you generate in U.S. sales 
revenue? Please include specific figures.

    Answer. The biopharmaceutical industry is one of the most research-
intensive industries in the United States In 2017, NIH had a budget of 
$39.2 billion, only a fraction of which, $3.2 billion, was dedicated to 
drug discovery. The industry invested over $90 billion in R&D--almost 
30 times more. For Pfizer alone, we invested approximately $8 billion 
in R&D last year.

    Pfizer's number one priority is always the care of our patients, 
and we are proud of the investments Pfizer makes to insure we continue 
to bring new, innovative cures to patients. These responsibilities 
require investments in R&D, manufacturing and other areas to accomplish 
our mission of creating breakthrough medicines that change people's 
lives.

    In 2018, Pfizer's revenues in the United States totaled 
approximately $25 billion and Pfizer spent approximately $20 billion on 
global R&D and manufacturing. This includes investing in state-of-the-
art labs so we can attract the finest scientists in the world and 
continuing to invest in innovative, high-tech manufacturing to ensure 
the high quality of our products.

    Question. Do you invest more in R&D than you spend on marketing and 
administration? What company functions do you consider to be included 
in administration? Please include specific figures.

    Answer. In order to fulfill Pfizer's mission to create breakthrough 
medicines that change patients' lives, we invest in several areas to 
ensure an innovative pipeline, top-quality manufacturing, and education 
of patients and physicians to ensure they have the information they 
need to make knowledgeable decisions about patient care.

    In 2018, Pfizer spent approximately $14 billion on selling, 
informational and administrative expenses and approximately $8 billion 
on R&D. Selling, informational and administrative costs are expensed as 
incurred. Among other things, these expenses include the internal and 
external costs of marketing, advertising, shipping and handling, 
information technology and legal defense.

    Question. Do you invest more in R&D than you spend on marketing and 
sales? What company functions do you consider to be included in sales? 
Please include specific figures.

    Answer. In order to fulfill Pfizer's mission to create breakthrough 
medicines that change patients' lives, we invest in several areas to 
ensure an innovative pipeline, top-quality manufacturing, and education 
of patients and physicians to ensure they have the information they 
need to make knowledgeable decisions about patient care.

    In 2018, Pfizer spent approximately $6.9 billion on direct sales & 
marketing and approximately $8 billion on R&D globally. Direct sales 
and marketing expenses include, among other things: direct promotion or 
sale of the company's products.

    Question. Why do you advertise for the drugs you manufacture? What 
factors do you consider in choosing which drugs you advertise?

    Answer. Pfizer believes that direct-to-consumer (DTC) advertising 
should be, first and foremost, a tool through which we can provide 
patients with useful information about their medical conditions, the 
availability of treatments and the potential benefits and risks of 
available treatment options so they can have a discussion with their 
doctors and take an active role in managing their health. Research has 
confirmed that this communication channel delivers on this goal.\13\
---------------------------------------------------------------------------
    \13\ See 2017 Direct to Consumer Advertising Survey Results, 
presented by Princeton Survey Research Associates International, 
prepared for PhRMA, https://www.phrma.org/report/2017-direct-to-
consumer-advertising-survey-results; DIA, Therapeutic and Regulatory 
Science, https://journals.sagepub.com/doi/abs/10.1177/2168479017708226; 
https://www.fda.gov/AboutFDA/CentersOffices/
OfficeofMedicalProductsandTobacco/CDER/ucm090276.htm#Completed.

    We may consider several factors when making decisions about our 
consumer communications. Some of these may include the information 
needs of patients who might benefit from one of our medicines and/or 
the extent to which a health condition is un- and under-diagnosed and 
---------------------------------------------------------------------------
treated.

                                 ______
                                 
                              Pfizer Inc.

                             500 Arcola Rd.

                         Collegeville, PA 19426

                  Tel: 484-865-8937  Fax: 484-865-0090

                             www.pfizer.com

                       Peter Honig, M.D., M.P.H.

                         Senior Vice President

                    Worldwide Safety and Regulatory

May 30, 2018

Scott Gottlieb, M.D.
Commissioner
Food and Drug Administration
10903 New Hampshire Avenue
Silver Spring, MD 20993-0002
[email protected]

Re:  Reference Listed Drug (RLD) Access Inquiries Website and NDA 
022321 for Embeda (morphine sulfate; naltrexone hydrochloride) 
Extended-
Release Capsules; NDA 017989 for Hemabate (carboprost tromethamine) 
Injection; and NDA 020931 for Tikosyn (dofetilide) Capsules

Dear Dr. Gottlieb:

We write in reference to the newly posted page on the FDA website 
entitled ``Reference Listed Drug (RLD) Access Inquiries.'' \1\ We note 
that several new drug applications (NDAs) owned by Pfizer Inc. or 
wholly-owned subsidiaries of Pfizer (collectively, ``Pfizer'') are 
included in the list published on this site (``List''):
---------------------------------------------------------------------------
    \1\ https://www.fda.gov/Drugs/DevelopmentApprovalProcess/
HowDrugsareDevelopedandAp
proved/ApprovalApplications/AbbreviatedNewDrugApplicationANDAGenerics/
ucm607738.htm.

    1.  Embeda (morphine sulfate; naltrexone hydrochloride), NDA 
022321;
    2.  Hemabate (carboprost tromethamine), NDA 01 7989; and
    3.  Tikosyn (dofetilide), NDA 020931.

We write to the Agency for several reasons. First, we wish to inform 
the Agency about Pfizer's internal practice for handling drug 
purchasing inquiries from prospective generic applicants, as well as 
provide some context for why the Agency may have received inquiries 
about these particular products, and Pfizer's diligence in addressing 
these issues. We believe that this information demonstrates Pfizer's 
commitment to supporting innovation and a competitive marketplace. 
Second, we wish to provide our suggestions on additional, non-
confidential information to add to the List in order to provide context 
critical to understanding the List and its value. Additionally, we wish 
to express our concerns that the Agency's announcement surrounding the 
new webpage and how the information is currently presented implies that 
the companies listed have engaged in ``gaming'' or anti-competitive 
behavior, which is untrue with respect to Pfizer, and not supported by 
the facts currently included in the List.

Pfizer was surprised and disappointed to discover that FDA had been 
informed by prospective generic applicants that they had difficulty 
obtaining some of our products to conduct the testing necessary to 
support submission of an abbreviated new drug application (ANDA). 
However, we note that the Agency included a disclaimer on the webpage 
stating that ``[w]e note that FDA has not independently investigated or 
confirmed the access limitations described in the inquiries received.'' 
\2\ As discussed in more detail below, without having any additional 
information about these inquiries, Pfizer is unable to confirm whether 
those inquiries were made to Pfizer, and if so, whether they were 
handled in accordance with Pfizer's practice to make its drug products 
available to applicants for purchase.
---------------------------------------------------------------------------
    \2\ https://www.fda.gov/Drugs/DevelopmentApprovalProcess/
HowDrugsareDevelopedandAp
proved/ApprovalApplications/AbbreviatedNewDrugApplicationANDAGenerics/
ucm607738.htm.

Following publication of the List, Pfizer conducted internal due 
diligence to identify whether Pfizer was contacted by prospective 
generic applicants for the listed products, and whether Pfizer was able 
to provide those customers with the requested drug product. By way of 
background, our standard approach is to ensure that drug product is 
available to licensed generic manufacturers at the listed price and on 
Pfizer's standard terms of sale.\3\ The vast majority of Pfizer's 
products are available through traditional wholesale channels (i.e., 
available through one or more of Pfizer's authorized distributors). If 
Pfizer receives an inquiry about a product that is available at 
wholesale, Pfizer will refer a prospective buyer to a publicly 
available list of its authorized distributors, and indicate that the 
prospective buyer should obtain product from an authorized distributor 
on that list. For the limited number of products that are not available 
at wholesale, requests made to Pfizer by a generic manufacturer wishing 
to purchase drug samples should be fulfilled in accordance with 
Pfizer's standard practice. If such requests involve a product with a 
REMS that restricts distribution, Pfizer's position is that a Safety 
Determination Letter (SDL) needs to be provided prior to sale. Pfizer 
developed an internal process to handle such requests in early 2015, 
upon realizing that such requests come into Pfizer via multiple 
departments and colleagues.
---------------------------------------------------------------------------
    \3\ If a drug product is in critical short supply, Pfizer will ship 
products to fulfill orders for dispensing to patients before fulfilling 
orders for product for testing.
---------------------------------------------------------------------------

Tikosyn

The List indicated that the Agency had received four inquiries 
regarding Tikosyn. To the best of its knowledge, Pfizer is aware of 
only one request for Tikosyn from a prospective generic applicant. At 
the time of that request, Tikosyn was approved with a REMS with 
elements to assure safe use (ETASU) that restricted distribution. When 
contacted by the applicant, Pfizer requested that the applicant provide 
us with written confirmation from the Agency that Pfizer's sale of the 
product to the applicant would not be considered a violation of our 
REMS. The applicant did not contact Pfizer further and Pfizer never 
received any written correspondence from the Agency. The Agency removed 
the REMS in 2016, and Pfizer notes that the Access Inquiries Webpage 
indicates that FDA never issued any SDLs for this drug product.

We note despite the inquiries submitted to the Agency identified in the 
List, ANDAs have been submitted and approved for the drug product. 
There are three approved ANDAs for the drug product, with the first 
approved on June 6, 2016,\4\ and two additional ANDAs approved in 
2018.\5\ Additionally, the Agency's paragraph IV certification list 
indicates that the first ANDA containing a paragraph IV certification 
was submitted on May 1, 2014, when the REMS was still in place.\6\ This 
additional information indicates that applicants were able to obtain 
product, submit ANDAs, and obtain approval from the approval even while 
the REMS was in place.
---------------------------------------------------------------------------
    \4\ ANDA 207058, see https://www.accessdata.fda.gov/scripts/cder/
ob/results_product.cfm?Ap
pl_Type=A&Appl_No=207058, accessed May 23, 2018.
    \5\ ANDA 208625, see https://www.accessdata.fda.gov/scripts/cder/
ob/results_product.cfm?Ap
pl_Type=A&Appl_No=208625, accessed May 23, 2018; ANDA 207746, see 
https://www.
accessdata.fda.gov/scripts/cder/ob/
results_product.cfm?Appl_Type=A&Appl_No=207746, accessed May 23, 2018.
    \6\ See https://www.fda.gov/downloads/Drugs/
DevelopmentApprovalProcess/HowDrugsareDe
velopedandApproved/ApprovalApplications/
AbbreviatedNewDrugApplicationANDAGenerics/UC
M293268.pdf.

As the REMS has been removed by the Agency, Pfizer now makes Tikosyn 
available at wholesale through its authorized distributors.

Embeda

The List indicated that the Agency received one inquiry regarding 
Embeda. We note that despite the inquiry submitted to the Agency, ANDAs 
containing a paragraph IV certification were submitted to the Agency 
for Embeda from May 3, 2010, through May 28, 2010, covering five of the 
six approved strengths of Embeda.\7\ Pfizer acquired King 
Pharmaceuticals (and with it, Ernbeda) on March 1, 2011. Two weeks 
later, Pfizer recalled Embeda from the market due to stability issues 
with the product. Pfizer spent the next several years diligently 
addressing the issues that led to the recall, and Pfizer was able to 
re-launch the product in January 2015. However, as a result of these 
issues, from March 2011 through January 2015, there was no Embeda 
product available for sale in the U.S. market.
---------------------------------------------------------------------------
    \7\ See https://www.fda.gov/downloads/Drugs/
DevelopmentApprovalProcess/HowDrugsareDe
velopedandApproved/ApprovalApplications/
AbbreviatedNewDrugApplicationANDAGenerics/UC
M293268.pdf.

Pfizer was not able to identify any request from a generic applicant to 
purchase Embeda. Embeda is now available at wholesale through Pfizer's 
authorized distributors.

Hemabate

Finally, the List indicated that FDA had received one inquiry for 
Hemabate, an older drug owned by Pharmacia and Upjohn Co., which was 
acquired by Pfizer in 2003. Pharmacia, and later Pfizer, limited 
Hemabate distribution to customers with medical and surgical intensive 
care facilities to help ensure the drug product was used in accordance 
with the product's labeling. While this limited distribution may have 
prevented a prospective generic applicant from acquiring the drug 
product from a wholesaler, it would not have prevented an applicant 
from contacting Pfizer directly to buy the drug product. Pfizer ceased 
the limited distribution of Hemabate to ensure patients and healthcare 
professionals had appropriate access to the drug product. The product 
is now available at wholesale through Pfizer's authorized distributors 
since January 2018. Pfizer was not able to identify any request from a 
generic applicant to purchase Hemabate.

Proposed Revisions to the List

We encourage the Agency, in accordance with its goal ``[t]o help 
address this issue and to provide transparency regarding these 
inquiries,'' \8\ to add further information to the List. The 
information Pfizer suggests the Agency include will provide critical 
context to help clarify to the stakeholders involved, i.e., the 
American public, the United States Government, and industry, whether an 
NDA bolder may be preventing generic applicants from obtaining the drug 
products necessary to support submission of an ANDA Without this 
information, stakeholders may come away with the false impression that 
every company on the List has impeded access, as demonstrated by the 
news coverage of the List and FDA's statements.\9\
---------------------------------------------------------------------------
    \8\ https://www.fda.gov/Drugs/DevelopmentApprovalProcess/
HowDrugsareDevelopedandAp
proved/ApprovalApplications/AbbreviatedNewDrugApplicationANDAGenerics/
ucm607738.htm.
    \9\ See, e.g., Sara Koblitz, FDA's Version of the Scarlet Letter, 
FDA Law Blog (May 23, 2018), http://www.fdalawblog.net/2018/05/fdas-
version-of-the-scarlett-letter/; Sheila Kaplan, ``F.D.A. Names and 
Shames Drug Makers to Encourage Generic Competition,'' The New York 
Times (May 17, 2018), https://www.nytimes.com/2018/05/17/health/drug-
prices-generics-fda.html; Sy Mukherjee, ``The FDA Is Naming and Shaming 
Companies Accused of Blocking Cheap Generic Drugs,'' Fortune (May 17, 
2018), http://fortune.com/2018/05/17/fda-database-generic-drug-delays/.

---------------------------------------------------------------------------
We recommend that the List include:

      The date the inquiry was made to FDA, and if furnished by the 
prospective generic applicant, the date(s) the applicant attempted to 
acquire the drug product and failed;
      If available, whether the prospective generic applicant directly 
approached the NDA holder or manufacturer , and was unable to obtain 
product that way;
      The identity of the NDA holder at the time the inquiry was made;
      Whether there are approved generic products for the drug 
product, and when those were approved;
      Whether and when an applicant submitted an ANDA with paragraph 
IV certification; and
      Whether a particular inquiry for a product with a REMS with 
ETASU restricting distribution included a protocol, and whether the 
Agency issued an SDL relating to that inquiry.

While the Agency includes a disclaimer on the Access Inquiries Webpage 
that it has not investigated or confirmed the access limitations 
described in the inquiries it received,\10\ the Agency's statements, 
both on its website and in public statements, strongly suggest that the 
Agency endorses the claim that access to biosamples was blocked for all 
products on the list. In reality, however, the only certain fact about 
the inquiries on the List is that a prospective applicant complained to 
FDA that it was unable to obtain the drug product. Neither Pfizer nor 
the FDA knows whether that is in fact the case, or, if it is, whether 
there are reasons the applicant did not obtain product that are not the 
result of ``gaming'' or anti-competitive tactics by NDA holders. For 
example, the drug may not be available due to a drug shortage, recall 
(as in the case of Embeda), or because the generic applicant did not 
actually try all avenues to obtain the drug product, such as contacting 
the NOA holder or manufacturer directly.
---------------------------------------------------------------------------
    \10\ https://www.fda.gov/Drugs/DevelopmentApprovalProcess/
HowDrugsareDevelopedandAp
proved/ApprovalApplications/AbbreviatedNewDrugApplicationANDAGenerics/
ucm607738.
htm.

Including this additional information in the List will shed light on 
the reasons the generic applicant may have been w1able to obtain the 
drug product, as well as indicate whether generic applicants were able 
to obtain the drug product, despite the inquiries received by FDA. For 
example, knowing the dates the inquiries were made could indicate 
whether the requests came during a time when the drug product was not 
being marketed, as in a recall situation, or when a REMS with ETASU 
that restricted distribution was in place that may have triggered the 
need for a review of the prospective generic applicant's protocol. And, 
knowing those dates will help industry perform its own due diligence to 
identify whether a request for drug product was inappropriately denied. 
Likewise, noting whether the prospective generic applicant stated 
whether it contacted the NDA holder or manufacturer will indicate 
whether the applicant reached out to a party that could provide the 
drug product, and will assist a company in determining whether its 
policy on providing drug product, such as Pfizer's, was appropriately 
---------------------------------------------------------------------------
followed.

Additionally, providing the identity of the NDA holder at the time of 
the inquiry will help clarify whether the company that currently owns 
the NDA could potentially be responsible for the failure to provide 
drug product, or whether that failure, if any, could be attributable to 
the prior holder of the NDA. For example, without knowing when the 
inquiry was made or who the NDA holder was at the time of the inquiry, 
Pfizer cannot tell for two of its products on the List (Embeda and 
Hemabate) whether those inquiries came before or after Pfizer's 
acquisition of the companies that originally owned those 
products.Accordingly, Pfizer cannot adequately respond to allegations 
that it may have inappropriately restricted access to its drug 
products.

Including the dates of generic entry would also demonstrate to 
stakeholders whether generic competition was impeded, or if in fact, 
one or more generic applicants were able to obtain the product needed 
in order to obtain approval from the Agency. While we recognize that 
the Agency may be unable to identify who made the inquiry to FDA, even 
if that applicant has an ANDA approved later, to the extent that 
information can be provided, it would demonstrate whether a particular 
generic applicant was blocked from obtaining product.

Additionally, providing more information related to products with REMS 
that restrict distribution, e.g., whether an applicant has submitted a 
protocol to the Agency, and whether a particular inquiry on the List 
correlates to the issuance of an SOL, will also indicate whether the 
generic applicant who made the inquiry provided its protocol to the 
Agency, and whether the Agency determined that the protocol contained 
safety protections comparable to the REMS. Currently, there is no 
indication as to whether an applicant who complained about not having 
access to such drug product took appropriate steps to facilitate its 
access to the product when there was such a REMS in place for the drug 
product.

Finally, we also note that the Agency does not inform an NOA holder in 
real time when an applicant has had difficulty obtaining product. Given 
Pfizer's policy to provide drug product when requested, if the Agency 
had informed Pfizer that it had received such an inquiry on a specific 
date, Pfizer could have then undertaken its own efforts to resolve the 
issue.

We appreciate the Agency's consideration of the issues raised in this 
letter, and reiterate our commitment to competition and innovation in 
the biopharmaceutical industry.

Sincerely,

Peter Honig, M.D., M.P.H.
Senior Vice President, Worldwide Safety and Regulatory

cc:  Janel Woodcock, M.D., Janet [email protected]
   Theresa Toigo, [email protected]
   Kathleen Uhl, M.D., [email protected]
   Maryll Toufanian, [email protected]

                                 ______
                                 
                U.S. Food and Drug Administration (FDA)
July 19, 2018

Peter Honig , M.D., M.P.H.
Senior Vice President, Worldwide Safety and Regulatory
Pfizer Inc.
Email: [email protected]

Dear Dr. Honig:

Thank you for your letter of May 30, 2018, regarding FDA's Reference 
Listed Drug (RLD) Access Inquiries webpage. Your letter informs FDA 
about Pfizer's internal practice for handling inquiries about samples 
from prospective generic applicants, provides suggestions about 
additional information to add to the RLD Access Inquiries webpage, and 
expresses concern about the Agency's announcement surrounding the 
webpage (Letter at 1-2). The Commissioner referred your letter to the 
Center for Drug Evaluation and Research (CDER) for response.

    1.  Pfizer's internal practice for handling drug purchasing 
inquiries from prospective generic applicants

Your letter provides a synopsis of Pfizer's internal practices for 
handling the inquiries that it receives related to RLD access to its 
products and the circumstances surrounding the Pfizer products that 
appear on the RLD Access Inquiries webpage (Letter at 2-3). We 
appreciate the insight provided by Pfizer on its internal processes. As 
you are aware, inclusion on the list of products on the RLD Access 
Inquiries webpage signifies that FDA has received an RLD access inquiry 
related to limited distribution of the product. As we state on the 
webpage, FDA has not independently investigated or confirmed the access 
limitations as described in the inquiries received.

You also state that FDA ``does not inform an NDA holder in real time 
when an applicant has had difficulty obtaining product'' and that ``if 
[FDA] had informed Pfizer that it had received such an inquiry on a 
specific date, Pfizer could have then undertaken its own efforts to 
resolve the issue.'' As the webpage explains (and as also described in 
the draft guidance for industry How to Obtain a Letter from FDA Stating 
that Bioequivalence Study Protocols Contain Safety Protections 
Comparable to Applicable REMS for RLD (How to Obtain a Letter 
Guidance)), FDA does notify certain RLD sponsors, after the prospective 
generic applicant has provided appropriate disclosure authorization to 
the Agency. However, to the extent that Pfizer has a process for 
prospective generic applicants to obtain samples, we encourage Pfizer 
to consider making that process public to help ensure both that 
interested developers know what process to use, and that Pfizer has 
access to as much information as possible about any access issues.

    2.  Suggestions for additional information Pfizer believes FDA 
should add to the RLD Access Inquiries webpage

Your letter also contains a list of six points of information Pfizer 
recommends be added to the RLD Access web page (Letter at 4):

          1.  The date the inquiry was made to FDA, and (if furnished 
        by the prospective generic applicant), the date(s) the 
        applicant attempted to acquire the product and failed;
          2.  If available, whether the prospective generic applicant 
        directly approached the NDA bolder or manufacturer, and was 
        unable to obtain product that way;
          3.  The identity of the NDA holder at the time the inquiry 
        was made;
          4.  Whether there are approved generic products for the drug 
        product, and when those were approved;
          5.  Whether and when an applicant submitted an ANDA with a 
        paragraph IV certification; and
          6.  Whether a particular inquiry for a product with a REMS 
        with ETASU impacting distribution included a protocol, and 
        whether the Agency issued a Safety Determination Letter (SDL) 
        relating to that inquiry.

We note that two of these items (``[t]he identity of the NDA holder at 
the time the inquiry was made,'' and ``whether the Agency issued a 
[Safety Determination Letter] relating to [an] inquiry'') are already 
included on the RLD Access Inquiries webpage. The webpage identifies 
the RLD sponsor associated with each inquiry, and clarifies that this 
is the RLD sponsor that was listed in the Approved Drug Products with 
Therapeutic Equivalence Evaluations (the Orange Book) at the time FDA 
received the inquiry (see footnote on the chart of inquiries). The web 
page also identifies whether FDA issued a Safety Determination Letter 
in connection with a particular RLD access inquiry (and explains that 
receipt of such a letter is preceded by FDA' s review of bioequivalence 
study protocols to assess whether they contain safety protections 
comparable to those in the applicable REMS for the RLD).

Two of the other points of information (``[w]hether there are approved 
generic products for the drug product, and when those were approved'' 
and ``[w]hether an applicant submitted an ANDA with a paragraph IV 
certification'') are already publicly available on FDA's website (via 
the Orange Book or Drugs@FDA and the Paragraph IV Certifications List, 
respectively).\1\ For the remaining points of information, to the 
extent FDA has access to the information you describe, we will take 
your feedback (along with feedback from other stakeholders) into 
account as we consider whether any changes to the RLD Access Inquiries 
webpage should be made in order to best address and improve 
transparency about this topic.
---------------------------------------------------------------------------
    \1\  See http://www.accessdata.fda.gov/scripts/cder/ob/index.cfm, 
http://www.accessdata.fda.
gov/scripts/cder/daf/index.cfm and https://www.fda.gov/downloads/Drugs/
DevelopmentApprovalProcess/HowDrugsareDevelopedandApproved/
ApprovalApplications/Abbre
viatedNewDrugApplicationANDAGenerics/UCM293268.pdf, respectively.

    3.  Concerns relating to the Agency's announcement surrounding the 
---------------------------------------------------------------------------
RLD Access Inquiries webpage

Your letter also indicates that FDA's presentation of information about 
this topic ``strongly suggest that the Agency endorses the claim that 
access to biosamples was blocked for all products on the list'' (Letter 
at 4). As you note, however, the RLD Access webpage makes clear that 
FDA has not independently investigated or confirmed the access 
limitations described in the inquiries the Agency received. The webpage 
is one effort under the FDA's Drug Competition Action Plan to provide 
transparency about the potential impact of this important issue. If 
generic companies are unable to purchase the samples they need to 
support their applications, this slows down, or entirely impedes, the 
generic drug development process--leading to delays in bringing 
affordable generic alternatives to patients in need. FDA is committed 
to advancing policies to help bring more competition to the 
prescription drug market, and we will continue to consider how we can 
best advance this goal, including whether any changes to the RLD Access 
Inquiries webpage should be made. We appreciate your feedback on this 
issue.

Thank you again for contacting us.

            Sincerely,

            Janet Woodcock, M.D.
            Director
            Center for Drug Evaluation and Research

                                 ______
                                 

                    PFIZER FOUNDATION GRANT SUMMARY

                               2015-2018

                           TOTAL: $45,877,000

GLOBAL HEALTH PROGRAMMING

NOTE: This report includes information for recipient both U.S. and ex-
U.S. recipient organizations. Certain Pfizer Foundation grants to non-
U.S. grantees are facilitated through U.S.-based donor-advised funds 
that specialize in vetting and processing grants to non-U.S. grant 
recipients.


           IMPROVING HEALTHCARE DELIVERY AND LOCAL INNOVATION
------------------------------------------------------------------------
    DATE BOARD
     APPROVED          PARTNER             DESCRIPTION          AMOUNT
------------------------------------------------------------------------
November 2015      Swasth           Global Health Innovation  $1,500,000
                    Foundation,      Grants support
                    Afya Research,   organizations that are
                    Jacaranda        advancing innovative
                    Heath,           health models in low
                    Northstar        and middle income
                    Alliance,        countries. The goal of
                    Penda Health,    this portfolio is to
                    World Health     improve healthcare
                    Partners,        delivery for
                    Clinicas del     underserved populations
                    Azucar,          and support local
                    Saluno, APOPO,   innovation in key
                    Ayzh, Last       countries: India,
                    Mile Health,     Kenya, Mozambique,
                    LifeNet          Mexico, Tanzania,
                    International,   India, Liberia, Uganda,
                    One Family       Rwanda, and South
                    Health,          Africa. The grants
                    Operation ASHA   support projects that
                    and Sevamob      align to the
                                     Foundation's 4
                                     strategic elements:
                                     primary healthcare
                                     delivery, women and
                                     children's health,
                                     health technologies for
                                     low resource settings
                                     and innovative
                                     financing mechanisms.
                                     The Foundation
                                     supported $100,000
                                     grants to fifteen
                                     organizations in 10
                                     countries.
------------------------------------------------------------------------
December 2016      Swasth           SECOND CYCLE: The          2,000,000
                    Foundation,      Foundation supported
                    Afya Research,   $100,000 grants to
                    Jacaranda        twenty organizations in
                    Heath,           10 countries.
                    Northstar
                    Alliance,
                    Penda Health,
                    World Health
                    Partners,
                    Clinicas del
                    Azucar,
                    Saluno, Ayzh,
                    Last Mile
                    Health,
                    LifeNet
                    International,
                    One Family
                    Health,
                    Operation ASHA
                    and Sevamob,
                    Purple Source,
                    Unjani,
                    AccuHealth,
                    Bive, Salud
                    Cercana,
                    2020MicroClini
                    c
------------------------------------------------------------------------
March 2018         Swasth           THIRD CYCLE: The           2,000,000
                    Foundation,      Foundation supported
                    Afya Research,   $100,000 grants to
                    Jacaranda        twenty organizations in
                    Heath,           12 countries.
                    Northstar
                    Alliance,
                    World Health
                    Partners,
                    Clinicas del
                    Azucar,
                    Saluno, Ayzh,
                    Last Mile
                    Health,
                    LifeNet
                    International,
                    One Family
                    Health,
                    Operation ASHA
                    and Sevamob,
                    Purple Source,
                    Unjani, Bive,
                    2020MicroClini
                    c, MUSO,
                    Possible, UE
                    Life Sciences
------------------------------------------------------------------------
March 2018         Acumen           The Foundation provided      500,000
                                     catalytic funding to
                                     Acumen America, an
                                     early-stage
                                     philanthropic venture
                                     fund that invests in
                                     companies that are
                                     improving the lives of
                                     low-income Americans
                                     and advancing
                                     innovative solutions to
                                     issues of poverty in
                                     America. Through this
                                     grant, Acumen will grow
                                     its portfolio of health
                                     investments that
                                     transform services for
                                     the poor in the US,
                                     including programs that
                                     will increase access to
                                     care, including
                                     lowering the financial
                                     and time burden of
                                     health and wellness on
                                     low-income individuals,
                                     improve quality of care
                                     to make care more
                                     effective, and improve
                                     patient experience of
                                     care to drive patient
                                     engagement & adherence.
                                     Portfolio companies
                                     include approaches to
                                     use technology to
                                     address and reduce
                                     health disparities for
                                     underserved and
                                     multicultural
                                     populations.
------------------------------------------------------------------------


                    IMPACT INVESTING CATALYTIC GRANTS
------------------------------------------------------------------------
    DATE BOARD
     APPROVED          PARTNER             DESCRIPTION          AMOUNT
------------------------------------------------------------------------
July 2015          PharmAccess      The Foundation provided   $1,500,000
                                     a grant to support the
                                     development and roll
                                     out of PharmAccess'
                                     innovative healthcare
                                     financing, funding
                                     which will help scale
                                     PharmAccess's mobile
                                     health (mHealth)
                                     wallet, a mobile health
                                     payment platform linked
                                     to M-Pesa in Kenya. The
                                     goal of the
                                     Foundation's grant is
                                     to support user roll-
                                     out of the platform and
                                     increase the number of
                                     people who use the
                                     platform, demonstrating
                                     its usability and
                                     collecting data. The
                                     Foundation's grant will
                                     target 100,000 low
                                     income, urban mothers
                                     who will be enrolled
                                     and receive a financial
                                     subsidy through the
                                     mHealth wallet to pay
                                     for healthcare services
                                     and products for their
                                     children under 5 years
                                     old.
------------------------------------------------------------------------
July 2015          PATH             The Foundation provided      350,000
                                     a grant to support the
                                     expansion of PATH's
                                     Global Health
                                     Innovation Hub in South
                                     Africa, in partnership
                                     with the South Africa
                                     Medical Research
                                     Council. The Hub's
                                     mission is to
                                     accelerate access to
                                     the most promising
                                     technology innovations
                                     by building the
                                     capacity of local
                                     innovators to develop,
                                     manufacture, and deploy
                                     global health
                                     technologies for
                                     vulnerable groups,
                                     leveraging PATH's
                                     expertise and network
                                     in global health and
                                     product development.
                                     The grant will support
                                     activities to build and
                                     accelerate local
                                     innovations and
                                     identify and prioritize
                                     local technologies that
                                     can deliver global
                                     health impact.
------------------------------------------------------------------------
July 2015          UNITUS           The Foundation provided      650,000
                                     a grant to support the
                                     expansion of
                                     `StartHealth,' a health
                                     technology jump-starter
                                     designed to accelerate
                                     the pace of development
                                     of bottom of the
                                     pyramid focused health-
                                     tech startups in India.
------------------------------------------------------------------------
July 2015          Global           The Foundation provided      500,000
                    Partnerships     a grant to this impact
                                     investment fund, which
                                     focuses on providing
                                     products and services
                                     using market based
                                     approaches in Latin
                                     America. This includes
                                     efforts to pilot and
                                     validate high potential
                                     health modes for last
                                     mile and underserved
                                     populations, with a
                                     focus on woman and
                                     children.
------------------------------------------------------------------------


 SUPPORT INNOVATIVE APPROACHES TO ENHANCING NON-COMUNICABLE DISEASE CARE
------------------------------------------------------------------------
   DATE BOARD
    APPROVED         PARTNER             DESCRIPTION            AMOUNT
------------------------------------------------------------------------
November 2015    FHI360          The Foundation provided a    $1,000,000
                                  grant to support the
                                  ``Suc Khoe Doi Dao''
                                  project that will
                                  establish a community-
                                  based, integrated NCD
                                  prevention and control
                                  program in Vietnam.
------------------------------------------------------------------------
November 2015    George          This partnership will         1,000,000
                  Institute of    pilot implementation of a
                  Global Health   novel primary care
                                  platform to support
                                  communities and
                                  healthcare providers in
                                  the prevention and
                                  management of NCDs in
                                  Indonesia and India.
------------------------------------------------------------------------
April 2016       PATH            As part of Pfizer               500,000
                                  Foundation's work to
                                  advance oncology care,
                                  the Foundation provided
                                  support to PATH in Peru
                                  to reduce the growing
                                  burden of illness and
                                  death from breast cancer
                                  for underserved
                                  populations through early
                                  detection linked to
                                  service and treatment.
------------------------------------------------------------------------
April 2016       Susan G Komen   As part of Pfizer               500,000
                  Breast Cancer   Foundation's work to
                  Foundation      advance oncology care,
                                  the Foundation provided
                                  support to Susan G Komen
                                  Breast Cancer Foundation
                                  in Northeast Brazil to
                                  integrate breast cancer
                                  patient support, early
                                  detection and timely/
                                  quality diagnosis into
                                  existing primary care
                                  services with the goal of
                                  improving health access
                                  and delivery for
                                  underserved women.
------------------------------------------------------------------------
April 2016       Partners in     As part of Pfizer               500,000
                  Health          Foundation's work to
                                  advance oncology care,
                                  the Foundation provided
                                  support to Partners in
                                  Health to increase
                                  accessibility of
                                  treatment for breast
                                  cancer for underserved
                                  patients and document and
                                  disseminate lessons
                                  learned to inform cancer
                                  care in Rwanda.
------------------------------------------------------------------------
April 2016       Indiana         As part of Pfizer               500,000
                  University      Foundation's work to
                  Center for      advance oncology care,
                  Global Health   the Foundation partnered
                                  with AMPATH, through the
                                  Indiana University Center
                                  for Global Health, to
                                  improve breast cancer
                                  services for underserved
                                  women in Kenya including
                                  screening, early
                                  diagnosis, treatment and
                                  palliative and
                                  survivorship care.
------------------------------------------------------------------------
April 2017       FHI360          The Foundation provided         300,000
                                  additional funding of the
                                  ``Abundant Health''
                                  project to support
                                  routine prevention,
                                  screening and management
                                  of hypertension and
                                  diabetes care in five
                                  commune health stations
                                  in Tan Phu district in Ho
                                  Chi Minh City, Vietnam.
------------------------------------------------------------------------
April 2017       PATH            The Foundation provided         350,000
                                  additional funding of the
                                  ``Community Based Program
                                  for Breast Health''
                                  project in Peru.
------------------------------------------------------------------------
August 2018      FHI360          The Foundation provided         437,000
                                  additional funding/phase
                                  two of the ``Abundant
                                  Health'' project to
                                  support routine
                                  prevention, screening and
                                  management of
                                  hypertension (HTN) and
                                  diabetes (DM) care at the
                                  community level.
------------------------------------------------------------------------
August 2018      PATH            The Foundation provided         230,000
                                  additional funding of the
                                  ``Community Based Program
                                  for Breast Health''
                                  project in Peru.
------------------------------------------------------------------------
August 2018      Indiana         The Foundation provided         250,000
                  University      additional funding to
                  Center for      AMPATH, through the
                  Global Health   Indiana University Center
                                  for Global Health, to
                                  improve breast cancer
                                  services for underserved
                                  women in Kenya including
                                  screening, early
                                  diagnosis, treatment and
                                  palliative and
                                  survivorship care.
------------------------------------------------------------------------
August 2018      George          The Foundation additional       150,000
                  Washington      funding to help improve
                  American        health outcomes and
                  Cancer          reduce health disparities
                  Institute       for African-American,
                                  Latina and LGBT women.
------------------------------------------------------------------------


    PROVIDING CRITICAL SUPPORT FOR PRESSING U.S. PUBLIC HEALTH NEEDS
------------------------------------------------------------------------
   DATE BOARD
    APPROVED        PARTNER              DESCRIPTION            AMOUNT
------------------------------------------------------------------------
April 2016       American        As part of Pfizer            $1,000,000
                  Cancer          Foundation's work to
                  Society         advance oncology care,
                                  the Foundation partnered
                                  with the American Cancer
                                  Society in Los Angeles,
                                  California and Hamptons
                                  Roads, Virginia to
                                  develop a patient
                                  navigation model that
                                  links community health
                                  advisors with federally-
                                  qualified health center
                                  (FQHC) screening and in-
                                  hospital navigation.
------------------------------------------------------------------------
April 2016       George          As part of Pfizer             1,000,000
                  Washington      Foundation's work to
                  American        advance oncology care,
                  Cancer          the Foundation provided
                  Institute       support to George
                                  Washington University
                                  Cancer Institute to help
                                  improve health outcomes
                                  and reduce health
                                  disparities for African-
                                  America, Latina and LGBT
                                  women.
------------------------------------------------------------------------
December 2017    West Virginia   The Foundation provided a       500,000
                  Department of   grant to support opioid
                  Health and      addiction prevention and
                  Human           education programming in
                  Resources       West Virginia.
------------------------------------------------------------------------
December 2017    New Hampshire   The Foundation provided a       500,000
                  Department of   grant to support opioid
                  Education       addiction prevention and
                                  education programming in
                                  New Hampshire.
------------------------------------------------------------------------
December 2017    Office of Drug  The Foundation provided a       500,000
                  Control         grant to support opioid
                  Policy          addiction prevention and
                                  education programming in
                                  Kentucky.
------------------------------------------------------------------------
December 2017    New Mexico      The Foundation provided a       500,000
                  Department of   grant to support opioid
                  Health          addiction prevention and
                                  education programming in
                                  New Mexico.
------------------------------------------------------------------------
December 2017    Utah            The Foundation provided a       500,000
                  Department of   grant to support opioid
                  Health          addiction prevention and
                                  education programming in
                                  Utah.
------------------------------------------------------------------------
December 2017    Commonwealth    The Foundation provided a       500,000
                  of              grant to support opioid
                  Massachusetts   addiction prevention and
                  Department of   education programming in
                  Public Health   Massachusetts.
------------------------------------------------------------------------
December 2017    Rhode Island    The Foundation provided a       500,000
                  Department of   grant to support opioid
                  Health          addiction prevention and
                                  education programming in
                                  Rhode Island.
------------------------------------------------------------------------
December 2017    Foundation for  The Foundation provided a       500,000
                  Appalachian     grant to support opioid
                  Ohio            addiction prevention and
                                  education programming in
                                  Ohio.
------------------------------------------------------------------------
December 2017    Department of   The Foundation provided a       500,000
                  Public Health   grant to support opioid
                                  addiction prevention and
                                  education programming in
                                  CT.
------------------------------------------------------------------------
December 2017    Delaware        The Foundation provided a       500,000
                  Health and      grant to support opioid
                  Social          addiction prevention and
                  Services        education programming in
                                  Delaware.
------------------------------------------------------------------------


             ADDRESSING KEY BARRIERS FOR WOMEN AND CHILDREN
------------------------------------------------------------------------
   DATE BOARD
    APPROVED         PARTNER            DESCRIPTION            AMOUNT
------------------------------------------------------------------------
July 2015        Save the        The Foundation provided a      $500,000
                  Children        grant to support a pilot
                                  program offering an
                                  integrated approach to
                                  delivering immunization
                                  and family planning
                                  services. The grant
                                  supported development of
                                  materials and tools for
                                  healthcare workers to
                                  engage women on family
                                  planning services,
                                  including formal
                                  evaluation.
------------------------------------------------------------------------
November 2015    CARE            The Foundation provided a     1,000,000
                                  grant to support
                                  increased access to
                                  family planning and
                                  immunization in Benin by
                                  integrating both services
                                  into comprehensive
                                  delivery and
                                  strengthening of clinical
                                  skills and outreach.
------------------------------------------------------------------------
November 2015    FHI360          The Foundation provided a     1,000,000
                                  grant to support to
                                  develop a global
                                  monitoring and evaluation
                                  framework to assess task
                                  shifting in the delivery
                                  of family planning
                                  products and demonstrate
                                  the effectiveness and
                                  safety of using Community
                                  Health Workers to
                                  administer products.
------------------------------------------------------------------------
November 2015    IRC             The Foundation provided a     1,200,000
                                  grant to support
                                  increased access to
                                  family planning and
                                  immunization in Ethiopia
                                  and Uganda by integrating
                                  both services into
                                  comprehensive delivery
                                  and male engagement. The
                                  project focused on last
                                  mile and hard to reach
                                  communities.
------------------------------------------------------------------------
November 2015    PSI             The Foundation provided a     1,000,000
                                  grant to support
                                  increased access to and
                                  demand for contraception
                                  and reproductive health
                                  services in Uganda for
                                  women and adolescent
                                  girls
------------------------------------------------------------------------
November 2015    U.S. Fund for   The Foundation provided a     1,000,000
                  UNICEF          grant to support
                                  expanding national mobile
                                  health platforms that
                                  improve immunization
                                  coverage and delivery in
                                  Indonesia, Laos and
                                  Uganda in partnership
                                  with MOH.
------------------------------------------------------------------------
November 2015    World Vision    The Foundation provided a     1,000,000
                                  grant to support
                                  increased access to
                                  family planning and
                                  immunization in Kenya by
                                  integrating both services
                                  into comprehensive
                                  delivery, community
                                  mobilization and male
                                  engagement.
------------------------------------------------------------------------
August 2016      World Vision    The Foundation partnered      1,000,000
                                  with World Vision in
                                  Zimbabwe to identify gaps
                                  in immunization coverage
                                  for children, adolescents
                                  and adults and support
                                  efforts to develop a life
                                  course approach to
                                  immunization with the
                                  Ministry of Health. The
                                  focus of the project was
                                  to increase access to and
                                  use of basic childhood
                                  immunizations for
                                  children from birth to
                                  age 5, and HPV
                                  immunization for girls as
                                  well as maternal
                                  immunizations for
                                  pregnant women. In
                                  addition World Vision
                                  worked with the Ministry
                                  of Health to address
                                  adult immunization needs,
                                  barriers and gaps in
                                  community service.
                                  Activities included
                                  training village health
                                  workers, health facility
                                  staff and community and
                                  faith leaders to educate
                                  and mobilize their
                                  communities around
                                  immunization and promote
                                  vaccination. This project
                                  also supported the
                                  development of a national
                                  life course approach.
------------------------------------------------------------------------
August 2016      U.S. Fund for   The Foundation provided a     1,000,000
                  UNICEF          grant to help UNICEF
                                  improve immunization
                                  coverage in urban
                                  underserved communities
                                  in Asia (Cambodia,
                                  Myanmar, Mongolia and the
                                  Philippines), and to
                                  support UNICEF in
                                  conducting operational
                                  research to assess the
                                  feasibility of using
                                  current newborn
                                  immunization delivery
                                  programs to support life
                                  course immunization
                                  strategies and reach
                                  female populations with
                                  additional immunizations
                                  and reproductive health
                                  services. A centerpiece
                                  of this work is
                                  supporting the roll out
                                  of technology platforms
                                  that track immunization
                                  coverage and population
                                  registries.
------------------------------------------------------------------------
August 2016      UN FOUNDATION   The Foundation partnered      1,000,000
                                  with the UN Foundation's
                                  Shot@Life program to
                                  pilot a life course
                                  immunization approach
                                  with a focus on rubella.
                                  Activities include the
                                  development of culturally
                                  specific local
                                  communication materials
                                  on the importance of
                                  vaccination and answering
                                  concerns parents may have
                                  about immunization and
                                  life-long impacts, as
                                  well as an integrated
                                  marketing program
                                  featuring social media,
                                  digital assets and a U.S.-
                                  based media campaign.
------------------------------------------------------------------------
April 2017       IRC             The Foundation provided         800,000
                                  additional funding to
                                  existing programs in
                                  Uganda and Ethiopia to
                                  advance integrated
                                  immunization and family
                                  planning program.
------------------------------------------------------------------------
April 2017       Save the        The Foundation provided         250,000
                  Children        additional funding to
                                  existing programs in
                                  Malawi to advance
                                  integrated immunization
                                  and family planning
                                  program.
------------------------------------------------------------------------
July 2017        CARE            The Foundation provided         250,000
                                  additional funding to an
                                  existing program in Benin
                                  to advance integrated
                                  immunization and family
                                  planning program.
------------------------------------------------------------------------
July 2017        World Vision    The Foundation provided         300,000
                                  additional funding to an
                                  existing program in Kenya
                                  focused on integrated
                                  immunization and family
                                  planning.
------------------------------------------------------------------------
March 2018       CARE            The Foundation provided       1,000,000
                                  additional funding to
                                  support work in Benin,
                                  where mortality of
                                  mothers and children is
                                  high. The project works
                                  in 20 public health
                                  clinics to increase the
                                  uptake of two live saving
                                  interventions, childhood
                                  vaccinations and family
                                  planning, through
                                  integration of the two
                                  services. The project
                                  addresses two main
                                  challenges at the same
                                  time: a weak healthcare
                                  system and sociocultural
                                  barriers in the
                                  community, which both
                                  need to be overcome for
                                  women and children to
                                  have access to quality
                                  health services.
------------------------------------------------------------------------
March 2018       IRC             The Foundation provided       1,500,000
                                  additional funding to
                                  permit the IRC to expand
                                  their work with health
                                  partners in Ethiopia and
                                  Uganda to increase the
                                  use of immunization and
                                  family planning by
                                  reaching women with
                                  information and services
                                  at a critical time--the
                                  12 months following
                                  birth.
------------------------------------------------------------------------
March 2018       Save the        The Foundation provided       1,000,000
                  Children        additional funding to an
                                  existing program in
                                  Malawi to advance
                                  integrated immunization
                                  and family planning
                                  program with Save the
                                  Children.
------------------------------------------------------------------------
March 2018       World Vision    The Foundation provided       1,000,000
                                  funding for the second
                                  phase of this project,
                                  Increasing Use of Family
                                  Planning (FP) and
                                  Immunization Services in
                                  Kenya.
------------------------------------------------------------------------


                        DISASTER RELIEF RESPONSE
------------------------------------------------------------------------
    DATE BOARD
     APPROVED            PARTNER            DESCRIPTION         AMOUNT
------------------------------------------------------------------------
April 2015         American Red Cross   Cyclone Pam              $10,000
------------------------------------------------------------------------
June 2016          American Red Cross   West Virginia             25,000
                                         relief efforts
------------------------------------------------------------------------
June 2016          American Red Cross   Ecuador Earthquake        75,000
------------------------------------------------------------------------
June 2016          International        Ecuador Earthquake        75,000
                    Medical Corp.
------------------------------------------------------------------------
Sept-Oct 2016      American Red Cross   West Virginia             25,000
                                         relief efforts
------------------------------------------------------------------------
Sept-Oct 2016      American Red Cross   Ecuador Earthquake        75,000
------------------------------------------------------------------------
Sept-Oct 2016      International        Ecuador Earthquake        75,000
                    Medical Corp.
------------------------------------------------------------------------
Sept-Oct 2016      American Red Cross   Louisiana flooding        25,000
------------------------------------------------------------------------
Sept-Oct 2016      Direct Relief        Louisiana flooding        25,000
                    International
------------------------------------------------------------------------
Sept-Oct 2016      One SC Fund          Hurricane Matthew         50,000
                                         in SC
------------------------------------------------------------------------
Sept-Oct 2016      Direct Relief        Hurricane Matthew         50,000
                    International        in the US
------------------------------------------------------------------------
Sept-Oct 2016      Project Hope         Hurricane Matthew         50,000
                                         in Haiti
------------------------------------------------------------------------
Sept-Oct 2016      World Vision         Hurricane Matthew         50,000
                                         in Haiti
------------------------------------------------------------------------
Sept-Oct 2016      PSI                  Zika virus relief        100,000
                                         efforts
------------------------------------------------------------------------
Sept-Oct 2016      The CDC Foundation   Zika virus relief        500,000
                                         efforts
------------------------------------------------------------------------
Sept-Oct 2016      The CDC Foundation   Zika virus relief        500,000
                                         efforts
------------------------------------------------------------------------
Sept-Oct 2016      PAHO Foundation      Zika virus relief      1,000,000
                                         efforts
------------------------------------------------------------------------
Sept-Oct 2016      Florida State Dept   Zika virus relief      1,000,000
                    of Health            efforts
------------------------------------------------------------------------
Sept-Oct 2016      Texas Dept of        Zika virus relief      1,000,000
                    Health               efforts
------------------------------------------------------------------------
December 2016      American Red Cross   Louisiana flooding        25,000
------------------------------------------------------------------------
December 2016      Pinebelt Foundation  Mississippi               25,000
                                         flooding
------------------------------------------------------------------------
December 2016      American Red Cross   Peru and Colombia        100,000
                                         mudslide
------------------------------------------------------------------------
December 2016      UNICEF               Peru and Colombia        100,000
                                         mudslide
------------------------------------------------------------------------
Sept-Oct 2017      Americares           Hurricane Harvey--       125,000
                                         TX and LA
------------------------------------------------------------------------
Sept-Oct 2017      World Vision         Hurricane Harvey--       125,000
                                         TX and LA
------------------------------------------------------------------------
Sept-Oct 2017      American Red Cross   Hurricane Harvey--       250,000
                                         TX and LA
------------------------------------------------------------------------
Sept-Oct 2017      One America Appeal   Hurricane Irma--TX       500,000
                                         and FL
------------------------------------------------------------------------
Sept-Oct 2017      American Red Cross   Hurricane Irma--         400,000
                                         Puerto Rico/U.S.
                                         Virgin Islands
------------------------------------------------------------------------
Sept-Oct 2017      IFRC                 Hurricane Irma--         100,000
                                         Caribbean
------------------------------------------------------------------------
Sept-Oct 2017      American Red Cross   Hurricane Maria--        250,000
                                         Puerto Rico
------------------------------------------------------------------------
Sept-Oct 2017      American Red Cross   Mexico Earthquake        250,000
------------------------------------------------------------------------
Sept-Oct 2017      UNICEF               Mexico Earthquake        250,000
------------------------------------------------------------------------
Sept-Oct 2018      American Red Cross   California                50,000
                                         Wildfires
------------------------------------------------------------------------
Sept-Oct 2018      United Way of North  Hurricane Florence       100,000
                    Carolina
------------------------------------------------------------------------
Sept-Oct 2018      Central Carolina     Hurricane Florence       100,000
                    Community
                    Foundation
------------------------------------------------------------------------
Sept-Oct 2018      International        Hurricane Florence       200,000
                    Medical Corp.
------------------------------------------------------------------------
Sept-Oct 2018      American Red Cross   Hurricane Florence       100,000
------------------------------------------------------------------------
Sept-Oct 2018      International        Hurricane Michael        100,000
                    Medical Corp.
------------------------------------------------------------------------
Sept-Oct 2018      Florida Disaster     Hurricane Michael        100,000
                    Fund
------------------------------------------------------------------------
Sept-Oct 2018      Save the Children    Indonesia Tsunami        100,000
------------------------------------------------------------------------
Sept-Oct 2018      Direct Relief        Indonesia Tsunami        100,000
                    International
------------------------------------------------------------------------
Sept-Oct 2018      World Vision         Indonesia Tsunami        100,000
------------------------------------------------------------------------
Sept-Oct 2018      Physicians for a     California               100,000
                    Healthy California   Wildfires
------------------------------------------------------------------------


                                 ______
                                 

                      UNITED STATES DISTRICT COURT

                    EASTERN DISTRICT OF PENNSYLVANIA

PFIZER INC., Plaintiff,             Case No.
v.                                  JURY TRIAL DEMANDED
JOHNSON & JOHNSON and JANSSEN 
BIOTECH, INC., Defendants.

                               COMPLAINT

    For its Complaint, plaintiff Pfizer Inc. (``Pfizer'') alleges 
against defendants Johnson & Johnson and Janssen Biotech, Inc. 
(collectively, ``J&J''), as follows:

                         PRELIMINARY STATEMENT

    1. It is accepted national policy to promote price competition 
among pharmaceutical manufacturers after an originator firm's patent 
protection has expired. This policy extends to biologics, a unique 
category of medications that are derived from living organisms. As one 
lawmaker put it when adopting applicable legislation, such competition 
``is good for patient safety, consumer choice . . . and the healthcare 
system at large.'' This case is about J&J's efforts to suppress that 
competition and deprive society of those benefits by, among other 
things, imposing a web of exclusionary contracts on both health 
insurers and healthcare providers (e.g., hospitals and clinics) to 
maintain its stranglehold in respect of an important biologic, brand 
named Remicade, also known by its generic name, infliximab.

    2. For many patients suffering from chronic diseases such as 
rheumatoid arthritis, plaque psoriasis, and Crohn's disease, the best--
and sometimes the only--option for treatment is infusion therapy with 
infliximab. As these conditions are chronic in nature, patients often 
require long-term treatment and multiple infusions per year.

    3. J&J owned patents protecting infliximab and has been amply 
rewarded for its invention: Between 1998 and 2016, Remicade was the 
only infliximab product on the market. This position allowed Remicade 
to become J&J's best-selling drug by far, generating about $4.8 billion 
in U.S. sales in 2016 alone. In fact, Remicade is among the best 
selling drugs in the world. For most uses, at list price Remicade sells 
for about $4,000 per infused dose and about $26,000 for a full year of 
treatment. When Pfizer introduced its competing biologic Inflectra 
(infliximab-dyyb) in 2016, J&J deployed improper exclusionary tactics 
to maintain the dominance of its flagship product.

    4. Inflectra received marketing approval under the Biologics Price 
Competition and Innovation Act (``BPCIA''). Congress recognized the 
growing importance of biologics, as well as the growing costs 
associated with them, and passed the BPCIA in 2010. The purpose of the 
BPCIA, as its name suggests, is to foster meaningful price competition 
for long-entrenched branded biologic products--with the ultimate goal 
of lowering healthcare costs. To facilitate price competition, the 
BPCIA provides an abbreviated FDA approval pathway for ``biosimilar'' 
versions of branded biologic drugs. Biosimilars are products that the 
FDA has determined to have ``no clinically meaningful differences'' 
from the already approved biologic (sometimes referred to as the 
``reference listed drug'' or ``RLD'') in terms of safety, purity, and 
potency. Although the BPCIA was enacted in 2010, FDA procedures for 
implementing the Act did not become effective until a few years later, 
and biosimilars are only recently beginning to come onto the market, 
with the first biosimilar approval in 2015.

    5. On April 5, 2016, Inflectra received FDA approval as the first 
biosimilar to Remicade. Pfizer began shipping Inflectra in November 
2016 and set its initial list price, often referred to as the wholesale 
acquisition cost (or ``WAC''), at 15 percent below the then-current WAC 
of Remicade.\1\
---------------------------------------------------------------------------
    \1\ WAC is the manufacturer's published list price to wholesalers 
or direct purchasers, not including prompt pay or other discounts, 
rebates, or reductions in price.

    6. The threat from Inflectra did not go unnoticed by J&J. Within 
weeks of Inflectra's launch, J&J began to deploy what it publicly has 
termed its ``Biosimilar Readiness Plan.'' The core features of the plan 
are exclusionary contracts that foreclose Pfizer's access to an 
overwhelming share of consumers, coupled with anticompetitive bundling 
and coercive rebate policies designed to block both insurers from 
reimbursing, and hospitals and clinics from purchasing, Inflectra or 
---------------------------------------------------------------------------
other biosimilars of Remicade despite their lower pricing.

    7. J&J's actions with respect to Remicade exclude competition at 
multiple levels:

    8. Exclusive contracts with insurance company payers. Insurer 
decisions regarding reimbursement policies have a dramatic impact on 
which infliximab product will be stocked by healthcare providers such 
as hospitals and clinics. Because providers administer infliximab on 
site (it is an infusion product), they must use their own funds to 
stock the product, purchasing it for later use and relying upon 
subsequent reimbursement from insurers to recoup their expenses. Given 
the cost of biologic drugs generally, and Remicade in particular, there 
is almost no chance that providers will pay for a product that is not 
widely covered by insurers for fear of stocking a product that will not 
be reimbursed after the provider administers it to a patient, as even a 
single unreimbursed dose may cost the provider in excess of $4,000.

     Recognizing this, J&J has induced insurers to enter into 
contracts that require an explicit commitment not to cover Inflectra at 
all or to do so only in the rarest of circumstances--in effect, to make 
Remicade the only covered infliximab. As a direct result of these 
exclusive dealing contractual commitments, Inflectra is either not 
listed on the insurance company's medical policy--a published listing 
of the drugs approved for reimbursement under the insurer's medical 
benefit--or is designated reimbursable only in so-called ``fail first'' 
cases. The ``fail first'' exception, which requires that Remicade has 
been tried by and failed with respect to a given patient before a 
biosimilar infliximab can be reimbursed, is medically inappropriate and 
illusory in practice. If Remicade, which is an infliximab product, does 
not work for a patient, a physician would turn to a non-infliximab 
drug, not to Inflectra, which also is an infliximab product and has no 
clinically meaningful differences from Remicade. The spurious nature of 
J&J's ``fail first'' restriction is illustrated by the fact that in 
early 2017, before J&J's contracts took hold, the major insurers listed 
Inflectra at parity with Remicade--indicating that they saw no medical 
reason to favor one over the other.

     J&J's ``fail first'' contractual restrictions therefore have the 
same practical effect as pure exclusive contracts: both operate to 
exclude Inflectra from qualifying for reimbursement under the insurers' 
plans; both prevent the insurer from freely reimbursing for Inflectra 
or another biosimilar without breaching the contracts; and both 
foreclose Inflectra from competing for patients covered by those plans. 
J&J has entered into such contracts with all or nearly all national 
health insurance companies. These ``biosimilar-exclusion'' contracts, 
on their own, have foreclosed Inflectra's ability to vie for at least 
70 percent of commercially insured patients in the United States, 
including a significant number of commercially insured patients who 
reside in the Philadelphia area. But the foreclosure effects of those 
insurer contracts go well beyond the immediate impact on patients 
covered by the affected plans, as discussed below.

    9. Exclusionary rebates and bundling arrangements with insurance 
company payers. A key to J&J's ability to coerce insurers into 
accepting its exclusionary commitments is its denial of rebates to 
insurers that decline J&J's exclusivity commitments, thereby imposing a 
substantial financial penalty. In effect, J&J says to insurers, ``If 
you want to receive attractive rebates on Remicade for all your 
existing Remicade patients''--rebates which, for some insurers, run 
into the tens of millions of dollars annually--``you must agree to not 
reimburse for Inflectra, or to do so in the most limited of 
circumstances.'' In short, insurers that decline J&J's offer face a 
substantial financial penalty, and those that accept receive a payoff 
(multimillion dollar rebate payments) in return for their commitment to 
exclude biosimilars.

     J&J's threatened financial penalty is effective because there is 
a substantial base of patients across the country who are already 
controlling their diseases with Remicade and thus are unlikely to 
switch to a lower-priced biosimilar once available. Although 
biosimilars have no clinically meaningful differences in safety, 
purity, and potency from the biologic originator, they are not 
substitutable without the prescriber's approval (unlike generics for 
non-biologic drugs approved under the Hatch-Waxman structure, which are 
substitutable without a new prescription). And, although the FDA's 
approval permits physicians to switch from the originator to the 
biosimilar, and Pfizer believes they should consider doing so in 
appropriate circumstances, as a practical matter, existing-patient 
Remicade demand is economically incontestable, that is, not a realistic 
candidate for biosimilar firms to compete for. As the head of J&J's 
pharmaceuticals business told investors, ``the 70 percent of patients 
who are [already] stable on Remicade are highly unlikely to switch.'' 
\2\ J&J bundles this economically ``incontestable'' demand for Remicade 
with the portion of demand that is ``contestable'' for biosimilar 
firms-- new patients starting therapy with infliximab--by threatening 
to deny rebates on all Remicade prescriptions if any infliximab 
biosimilar prescriptions are reimbursed, effectively meaning insurers 
would have to forfeit their rebates and pay J&J's ever increasing price 
for the incontestable patients.
---------------------------------------------------------------------------
    \2\ Johnson & Johnson, Q3 2016 Results Earnings Call Transcript 
(Oct. 14, 2016), available at https://seekingalpha.com/search/
transcripts?term=johnson+%26+Johnson+biosimilar.

     J&J also bundles rebates on multiple different products, such 
that insurers that refuse to grant exclusivity to Remicade would be 
forced to pay higher prices and/or forego enhanced portfolio rebates. 
The net effect of these anticompetitive bundling practices is that the 
insurers subject to them have no real choice but to agree to J&J's 
exclusivity conditions. Insurers have made it clear to Pfizerthat its 
net cost for Inflectrawould need to be low enough to offset the loss of 
J&J rebates. Pfizer and other biosimilar firms cannot feasibly make up 
the difference for the J&J rebates (on the existing Remicade patient 
base) that insurers would lose if they declined J&J's conditions. 
Insurers have stated a desire to support biosimilars--and the lower 
per-unit prices they bring--but realistically cannot do so without 
incurring a substantial financial penalty imposed by J&J and thus 
potentially placing themselves at a disadvantage relative to insurers 
---------------------------------------------------------------------------
accepting J&J's rebates.

    10. J&J-engineered coverage restrictions impact provider purchasing 
behavior and thus magnify foreclosure. The foreclosure created by J&J's 
exclusionary insurer-level contracts goes well beyond the patients 
covered by these health insurers: Inflectra's coverage status has a 
spillover effect on the purchasing decisions of healthcare providers 
(as noted, the clinics, hospitals, and other institutions that purchase 
and administer infliximab) as well as the prescribing decisions of 
physicians affiliatedtherewith. Given the widespread gaps in 
Inflectra's insurance coverage--engineered by J&J--providers have 
overwhelmingly chosen to stock only Remicade (which is essentially 
universally covered given its long tenure and dominant position) rather 
than deal with the risk of possible denials of coverage for Inflectra. 
Thus, providers have declined to purchase Inflectra across the board, 
even for patients covered by insurance plans that do cover the product. 
To take one example, even though Inflectra is covered by Medicare and 
other government programs, providers have been unwilling to stock 
Inflectra even for potential use with such government-insured patients. 
As a result, not only is the federal government forced to continue 
reimbursing for Remicade, the more expensive product, but the effective 
foreclosure of biosimilars is expanded well beyond the 70 percent of 
commercially insured patients directly foreclosed by J&J's insurer 
contracts. Indeed, as of September 1, 2017, about 90 percent of 
healthcare provider accounts using infliximab had purchased no 
Inflectra at all. J&J has stoked providers' reluctance to purchase 
Inflectra by touting with providers the very lack of coverage for 
Inflectra created by J&J's own exclusionary contracts.

    11. Exclusionary rebates and bundling arrangements with healthcare 
providers. Beyond the spillover impact described above, J&J has also 
extended its practices of multi-product bundling and bundling of 
contestable and incontestable demand in contracts with healthcare 
providers.

    12. J&J's exclusionary plan has been remarkably effective at 
stifling competition: Today, almost no national commercial health 
insurer provides coverage for Inflectra (except under the spurious 
``fail first'' scenario), and the vast bulk of healthcare provider 
accounts using infliximab (approximately 90 percent) have not purchased 
Inflectra at all. Despite some coverage by regional and government 
plans, Inflectra has secured less than 4 percent of total infliximab 
unit sales in the U.S. as of September 1, 2017.

    13. The harm to Pfizer and to competition as a whole--and, 
ultimately, to consumers, businesses, and the U.S. government, who bear 
the brunt of rising healthcare costs nationwide--is manifest. In 
response to a new entrant offering lower prices for a product deemed to 
have ``no clinically meaningful differences'' from the incumbent's 
brand, basic economics would predict that market-wide prices would 
fall. Instead, the opposite has occurred. Since the time the FDA 
approved Inflectra and J&J implemented its publicly-stated plan to 
block biosimilars like Inflectra, J&J has raised the list price of 
Remicade by close to 9 percent and increased the amount the U.S. 
government reimburses for Remicade by more than $190 per infused dose. 
J&J's list price increases are not overcome by increased rebates and 
discounts: Remicade's ``average selling price'' (``ASP'')--which by 
federal law is an average of a drug's pricing after taking into account 
discounts, rebates, and other price concessions--actually has increased 
since Inflectra's entry. As of September 2017, Remicade's ASP was more 
than 10 percent higher than Inflectra's ASP. Pfizer has offered to 
guarantee clients that Inflectra would be less expensive unit-for-unit 
than Remicade during a contract term. Despite Inflectra's lower per-
unit prices, and J&J's escalating prices, Remicade has not lost any 
substantial volume or share of sales to Inflectra, even though FDA 
determined there to be no clinically meaningful differences between the 
two products.

    14. In July, J&J extolled the success of its scheme, noting that it 
had not ``seen much of an impact'' from Inflectra's entrance, and that 
J&J is ``especially well-
prepared to manage through the Remicade biosimilars.'' \3\ J&J also 
said it was confident that it could fend off even subsequent biosimilar 
entrants this year because of its exclusionary contracts: ``[W]e have 
our contracting in place with all the managed care organizations [e.g., 
health insurers].'' \4\ The net result is that patients (along with 
healthcare providers and the U.S. Government) have fewer choices and 
pay more than they should.
---------------------------------------------------------------------------
    \3\ Johnson & Johnson, Q2 2017 Results Earnings Call Transcript 
(July 18, 2017), available at https://seekingalpha.com/search/
transcripts?term=johnson+$26+Johnson+biosimilar.
    \4\ Id.

    15. Major stakeholders at every level of the healthcare marketplace 
---------------------------------------------------------------------------
are suffering as a result of J&J's competition-reducing actions:

      Most importantly, consumers suffer in the form of artificially 
inflated prices (including higher coinsurance payments, insurance 
premiums, and taxes), as well as reduced choice.

      Government programs, including Medicare--and ultimately 
taxpayers--suffer by having to pay artificially higher prices for the 
vast majority of their infliximab utilization.

      Pfizer, of course, suffers loss of sales, investment, and 
reputation as a result of J&J's success in securing commitments to 
disadvantage Inflectra.

    16. Pfizer brings this action under the antitrust laws of the 
United States to challenge J&J's anticompetitive conduct. If J&J's 
conduct is allowed to continue, its ``Biosimilar Readiness Plan'' will 
become the playbook for biologic originator firms seeking to preserve 
their dominance in the face of biosimilar competition--thus subverting 
the competition-enhancing objectives of the BPCIA.

    17. Allegations relating to Pfizer's conduct are based on personal 
knowledge; other allegations are based on Pfizer's research, publicly 
available sources, feedback from customers, and information and belief.

                              THE PARTIES

    18. Plaintiff Pfizer is a corporation organized and existing under 
the laws of Delaware. Pfizer's principal place of business in the 
United States is located at 235 East 42nd Street, New York, New York 
10017. Pfizer is a research-based international pharmaceutical company 
which researches, develops, manufactures, and sells pharmaceutical 
products across the spectrum, from branded innovator products to 
generics and over-the-counter medications. Pfizer is also committed to 
developing biosimilar medications to bring competition, lower prices, 
and choice to patients.

    19. Pfizer has commercialized Inflectra, a biosimilar to J&J's 
Remicade, through its partnership with Celltrion, the holder of the 
drug product's Biologics License Application. The FDA approved 
Inflectraas a biosimilar to Remicade on April 5, 2016.

    20. Defendant Johnson & Johnson is a corporation organized and 
existing under the laws of New Jersey. Johnson & Johnson's principal 
place of business in the United States is located at One J&J Plaza, New 
Brunswick, New Jersey 08933. Johnson & Johnson is an international 
pharmaceutical company--one of the largest in the world--and was the 
sole supplier of infliximab, marketed as Remicade, between 1998 and 
2016, when Inflectra came to market.

    21. Defendant Janssen Biotech, Inc. (``Janssen'') is a wholly owned 
subsidiary of Johnson & Johnson. Janssen is a corporation organized and 
existing under the laws of Pennsylvania. Janssen's corporate 
headquarters are located at 800 Ridgeview Drive, Horsham, Pennsylvania 
19044. Janssen co-owns or has licenses to the Remicade patents and 
performs the marketing for Remicade in the United States.

              JURISDICTION, VENUE, AND INTERSTATE COMMERCE

    22. This action arises under the antitrust laws of the United 
States, including Section 1 of the Sherman Act, 15 U.S.C. Sec. 1, 
Section 2 of the Sherman Act, 15 U.S.C. Sec. 2, Section 3 of the 
Clayton Act, 15 U.S.C. Sec. 14, and Sections 4 and 16 of the Clayton 
Act, 15 U.S.C. Sec. Sec. 15 and 26.

    23. Subject matter jurisdiction is founded on 28 U.S.C. 
Sec. Sec. 1331 and 1337(a).

    24. Johnson & Johnson may be found, transacts business, and is 
subject to personal jurisdiction in this judicial district.

    25. Janssen maybe found, transacts business, and is subject to 
personal jurisdiction in this judicial district.

    26. The violations of law alleged in this Complaint took place, in 
part, in this judicial district and have injured Pfizer in this 
district. Venue is therefore appropriate in the Eastern District of 
Pennsylvania under Section 12 of the Clayton Act, 15 U.S.C. Sec. 22, 
and under 28 U.S.C. Sec. Sec. 1391(b) and (c).

    27. The creation, marketing, sale, and distribution of Remicade and 
Inflectra, and the actions complained of in this Complaint, occur in 
and substantially affect interstate commerce.

                   FACTUAL AND REGULATORY BACKGROUND

          A. Biologics

    28. Biologics are treatments derived from living systems such as 
microorganisms or plant or animal cells. As the FDA explains: 
``Biological products include a wide range of products such as 
vaccines, blood and blood components, allergenics, somatic cells, gene 
therapy, tissues, and recombinant therapeutic proteins. Biologics can 
be composed of sugars, proteins, or nucleic acids or complex 
combinations of these substances, or maybe living entities such as 
cells and tissues. Biologics are isolated from a variety of natural 
sources--human, animal, or microorganism--and may be produced by 
biotechnology methods and other cutting-edge technologies. Gene-based 
and cellular biologics, for example, often are at the forefront of 
biomedical research, and may be used to treat a variety of medical 
conditions for which no other treatments are available.'' \5\ In 
contrast to most drugs, which are chemically synthesized and whose 
structure is known, most biologics are complex mixtures that are not 
easily identified or characterized.\6\
---------------------------------------------------------------------------
    \5\ See U.S. Food & Drug Administration, What Are ``Biologics'' 
Questions and Answers, https://www.fda.gov/aboutfda/centersoffices/
officeofmedicalproductsandtobacco/cber/ucm133077.htm (last visited 
Sept. 18, 2017).
    \6\ Id.

          B.  Congress Enacts the Biologics Price Competition and 
---------------------------------------------------------------------------
Innovation Act to Spur Price Competition for Biologic Medications

    29. Congress has made clear that competition in pharmaceuticals is 
to be encouraged, and, to that end, in 1984 enacted the Hatch-Waxman 
Act (``Hatch-Waxman''), which established an abbreviated pathway for 
approval of generic counterparts to non-biologic branded drug products. 
Before Hatch-Waxman, a generic applicant had to conduct the same kinds 
of safety and efficacy studies (including large clinical trials and the 
like) as the originating drug manufacturer. Such a process, which can 
cost hundreds of millions of dollars and take years to complete, was 
prohibitive for would-be generic entrants and led to the near absence 
of generic competition to branded drug products. Hatch-Waxman 
eliminated this hurdle; it allowed generic firms to rely upon the 
originator's safety and efficacy studies. Generic applicants need only 
show that their products use the same active pharmaceutical ingredient 
as the originator, and that their products are bioequivalent (e.g., 
that the generic product's uptake into the body is equivalent to the 
branded drug). A principal goal of Hatch-Waxman was to trigger price 
competition with originator products, many of which had enjoyed 
longstanding exclusivity. That goal has been achieved: According to the 
FDA, the competition spurred by Hatch-Waxman has saved more than $1.6 
trillion for patients and the healthcare system.\7\
---------------------------------------------------------------------------
    \7\ See Kathleen ``Cook'' Uhl, 2016: A Record-Setting Year for 
Generic Drugs, U.S. Food & Drug Administration (Feb. 24, 2017), 
available at https://blogs.fda.gov/fdavoice/index.php/2017/02/2016-a-
record-setting-year-for-generic-drugs/ (noting that ``2016 was a 
record-setting year for FDA's generic drug program,'' and that ``[o]ver 
the last 10 years, generic drugs have saved the U.S. healthcare system 
about $1.68 trillion'').

    30. However, for a number of reasons, biologic products generally 
are not covered by the Hatch-Waxman procedures. Nevertheless, given the 
success of Hatch-
Waxman in spurring competition for non-biologic medicines, Congress and 
nearly all stakeholders in the healthcare system have recognized the 
great desirability of having an analogous system for biologics.\8\
---------------------------------------------------------------------------
    \8\ See U.S. Food & Drug Administration, Implementation of the 
Biologics Price Competition and Innovation Act of 2009 (Feb. 12, 2016), 
available at https://www.fda.gov/drugs/
guidancecomplianceregulatoryinformation/ucm215089.htm (``The goal of 
the BPCI Act is similar, in concept, to that of the Drug Price 
Competition and Patent Term Restoration Act of 1984 (a.k.a. the `Hatch-
Waxman Act') which created abbreviated pathways for the approval of 
drug products under Federal Food, Drug, and Cosmetic Act (FFD&C 
Act).'').

    31. In 2009, Congress addressed the need for competition in the 
biologics marketplace by introducing the BPCIA, which was signed into 
law in 2010. The Act furthers the ``FDA's longstanding policy of 
permitting appropriate reliance on what is already known about a drug, 
thereby saving time and resources and avoiding unnecessary duplication 
of . . . testing.'' \9\
---------------------------------------------------------------------------
    \9\ U.S. Food & Drug Administration, Implementation of the 
Biologics Competition and Innovation Act of 2009, https://www.fda.gov/
Drugs/GuidanceComplianceRegulatoryInformation/ucm215089.htm (last 
visited Sept. 18, 2017).

    32. A principal purpose of the Act--as reflected in its very name 
(i.e., the Biologics Price Competition and Innovation Act)--was to spur 
---------------------------------------------------------------------------
price competition in biologic drug products:

          ``We have to find a way to introduce competition into [the 
        biosimilar] market,'' including balancing ``giving incentives 
        for development of new products but bringing about the benefits 
        of competition in the marketplace.'' (Hon. Henry Waxman, United 
        States Representative from California)

          ``Legislation to facilitate the development of biosimilars 
        should promote competition and lower prices[.]'' (Hon. Anna G. 
        Eshoo, United States Representative from California)

          ``We want to foster a robust biosimilar market.'' (Hon. Joe 
        Barton, United States Representative from Texas)

          ``[C]ompetition [from biosimilars] is good for patient 
        safety, consumer choice, and drive[s] savings for consumers and 
        the healthcare system at large.'' (Hon. Gene Green, United 
        States Representative from Texas)

    33. The BPCIA provides an abbreviated regulatory approval pathway 
for the introduction of biosimilars. A biosimilar applicant may rely on 
the clinical studies of the reference listed drug if it can show: (a) 
that the proposed biosimilar is ``highly similar to the [originator 
product, or RLD] notwithstanding minor differences in clinically 
inactive components''; and (b) that ``there are no clinically 
meaningful differences between the [proposed biosimilar] and the [RLD] 
in terms of safety, purity, and potency'' (42 U.S.C. Sec. 262(i)(2)).

    34. Although biosimilars have no clinically meaningful differences 
in safety, purity, and potency from the RLD, they are not automatically 
substitutable with the RLD (unlike Hatch-Waxman generics). Thus, if a 
doctor prescribes the RLD, a pharmacist cannot substitute a biosimilar 
unless that product has been designated as interchangeable by FDA and 
the relevant state law permits substitution of interchangeable 
biologics.\10\ This allows originator firms to retain the bulk of their 
existing patient bases, which typically is not possible for a branded 
firm to do when a Hatch-Waxman generic enters (because state 
substitution laws permit prescriptions for the brand to be 
automatically substituted with the Hatch-Waxman generic by the 
pharmacist without the need for physician intervention). This 
difference enables biologic originator firms to leverage their 
monopolies over existing patients to extract anticompetitive 
commitments from insurers and providers.
---------------------------------------------------------------------------
    \10\ The BPCIA does provide for an ``interchangeable'' designation, 
but FDA published draft guidelines for establishing interchangeability 
only this year. U.S. Food and Drug Administration, Considerations in 
Demonstrating Interchangeability With a Reference Product (Draft 
Guidance) (Jan. 17, 2017). And while Pfizer believes that Inflectra can 
be safely and effectively substituted for Remicade (indeed, studies 
have shown that switching patients can be done safely and effectively, 
and Pfizer has supported and/or taken part in some of these studies), 
it will be years before Inflectra or any other biologic receives a 
formal ``interchangeability'' designation from FDA in the United 
States. Nonetheless, neither the BPCIA nor FDA contemplates that 
biosimilars should be prevented from competing in themarketplace--i.e., 
that consumers should be denied access to them--until they are 
designated interchangeable.

---------------------------------------------------------------------------
          C. Infliximab

    35. Infliximab is a tumor necrosis factor (``TNF'')-inhibiting 
biologic drug used to treat a range of immune-mediated diseases, 
including Crohn's disease, ulcerative colitis, rheumatoid arthritis, 
psoriatic arthritis, ankylosingspondylitis, and plaque psoriasis.

    36. As a biologic, infliximab is not synthesized in a laboratory, 
but rather derived from a living organism. Infliximab is a chimeric 
IgG1k monoclonal antibody (composed of human constant and murine 
variable regions) specific for human tumor necrosis factor-alpha. 
Infliximab is produced by a recombinant cell line cultured by 
continuous perfusion and is purified by a series of steps that includes 
measures to inactivate and remove viruses.

    37. Infliximab is an infusion therapy, meaning it is administered 
intravenously. Thus, infliximab patients must (in most cases) visit 
clinics, hospitals, or other medical facilities to receive the therapy 
from healthcare professionals. As a result, patients rarely purchase 
infliximab themselves at retail pharmacies. Instead, infusion centers, 
clinics, and hospitals purchase infliximab, and after administration, 
seek reimbursement from the patient's insurer or a government payer 
(e.g., Medicare). Infliximab is an important medicine that has provided 
life-changing benefits to millions of patients.

          D. J&J's Remicade

    38. J&J introduced the first infliximab product in the United 
States in 1998, under the brand name Remicade.

    39. Remicade is widely used: An estimated 475,000 patients in the 
U.S. receive at least one dose of Remicade annually. This fact, 
combined with the cost (approximately $4,000 per infused dose at list 
price), makes administering Remicade a major expense item for insurers 
and healthcare providers.

    40. J&J's list price increases for Remicade and other pricing 
actions have resulted in consistent increases in Remicade's ASP. J&J 
has increased the price of Remicade without experiencing a loss of 
sales to other therapies. Instead, Remicade sales have increased 
steadily since it was introduced. Indeed, J&J has been able to continue 
raising the price of Remicade notwithstanding the arrival of Inflectra.

    41. Since 1998, J&J has made billions of dollars in profit on 
Remicade.

          E. Pfizer's Inflectra

    42. Beginning in 2008, Celltrion undertook to develop a biosimilar 
to Remicade and move it through the intensive FDA review process. The 
Biologics License Application for Inflectra was filed with FDA in 2014. 
After rigorous scientific review, FDA approved infliximab-dyybon April 
5, 2016. In the FDA news release announcing its approval of Inflectra, 
the director of FDA's Center for Drug Evaluation and Research 
reiterated that approval as a biosimilar reflects a determination of 
``no clinically meaningful differences'' from the originator, and 
stated that ``[p]atients and the health care community can be confident 
that biosimilar products are high quality and meet the agency's 
rigorous scientific standards.'' \11\
---------------------------------------------------------------------------
    \11\ See U.S. Food and Drug Administration, FDA Approves Inflectra, 
A Biosimilar to Remicade (Apr. 5, 2016), https://www.fda.gov/
newsevents/newsroom/pressannouncements/ucm494227.
htm.

    43. J&J claimed patent protection over Remicade--as noted, making 
it the sole provider of infliximab for nearly two decades--and thus 
Pfizer and Celltrion were forced to defend against J&J's patent suit in 
parallel with FDA's regulatory review of the Inflectra application. On 
August 17, 2016, J&J's patent covering the infliximab antibody was 
ruled invalid by the United States District Court for the District of 
Massachusetts, a ruling which confirmed that J&J had no valid right to 
exclude Pfizer (or other potential biosimilar entrants). The Court held 
that the antibodies covered by J&J's Remicade patent had been disclosed 
and claimed in an earlier patent.\12\ Just a few months after the 
district court ruling, the U.S. Patent and Trademark Office issued a 
final decision in a re-examination of the same patent, holding that the 
patent was invalid.\13\
---------------------------------------------------------------------------
    \12\ Janelle Lawrence, J&J Remicade Patent Found Invalid in U.S. 
Victory for Pfizer, Bloomberg (Aug. 17, 2016), https://
www.bloomberg.com/news/articles/2016-08-17/j-j-patent-on-remicade-
expiring-in-2018-invalid-judge-rules.
    \13\ Id.

    44. After overcoming these hurdles, and after a 180-day notice 
period required by the BPCIA, Pfizer began selling Inflectra in 
---------------------------------------------------------------------------
November 2016.

    45. Inflectra is approved for all the same indications as Remicade, 
except pediatric ulcerative colitis, as to which J&J continues to enjoy 
an FDA-granted period of exclusivity because of the indication's status 
as an ``orphan'' indication (established on proof that the number of 
people affected by the disease or condition for which the drug is to be 
developed is fewer than 200,000 persons), which is scheduled to end in 
2018. On that date, Inflectra will be eligible to seek approval for 
pediatric ulcerative colitis. In any event, this indication accounted 
for less than 5 percent of overall infliximab utilization in 2016.

    46. Pfizer introduced Inflectra with a list price 15 percent lower 
than Remicade's, and, in negotiations with insurers and providers, 
offered substantial additional pricing concessions in the form of 
discounts and/or rebates that in some instances were more than 40 
percent below Inflectra's list price. The goal and effect was to offer 
Inflectra for less than J&J was offering Remicade; indeed, for many 
customers, Pfizer committed to ensure that Inflectra would have a lower 
net per-unit price than Remicade.

    47. Given that it was charging a lower price for Inflectra than J&J 
was charging for Remicade, Pfizer was optimistic that it would have an 
opportunity to compete, to secure a reasonable share of the business, 
particularly for new patients, and to bring the benefits of price 
competition to consumers, providers, insurers, and the U.S. government. 
However, due to J&J's exclusionary conduct, competition has been 
foreclosed. J&J maintains its monopoly and has continued to capture 
over 96 percent of infliximab sales even while maintaining prices far 
above competitive levels.

          F.  The Importance of Insurance Coverage for Infliximab 

    48. Most patients who are prescribed Remicade have some form of 
insurance coverage or qualify for patient assistance. The sources of 
insurance coverage are (a) private insurance, accounting for about 60 
percent of patients nationally, and (b) government insurance programs 
(principally Medicare and Medicaid), accounting for the remaining 40 
percent. Insurance coverage and reimbursement are therefore key to the 
adoption of the product by patients and healthcare providers alike. If 
a product as expensive as Remicade is not widely reimbursed, it will 
not be significantly utilized.

    49. Because Remicade is not dispensed in a retail pharmacy but 
rather administered intravenously in a clinic or other institutional 
setting, it generally is not included under the ``pharmacy benefit'' of 
most health plans. In the pharmacy benefit setting, physicians 
prescribe a drug and the patient procures the medication him or herself 
at the pharmacy, paying for it with a combination of insurance coverage 
(either private or government-sponsored) and out-of-pocket payment 
(usually, a co-pay). In the pharmacy benefit context, neither the 
prescribing physician nor the institution with which the physician is 
affiliated bears financial risk with respect to the drug selected, 
i.e., the drug is not purchased and stocked in advance by providers at 
their own cost. The pharmacy buys the drug, dispenses it, and is 
reimbursed.

    50. In contrast, ``medical benefit'' products such as Remicade are 
administered at a clinic or other healthcare provider site, and the 
provider itself first purchases the drug product for use in the 
infusion treatment of patients, and then later seeks reimbursement for 
the drug from a third party payer (a practice commonly referred to as 
``buy and bill''). When a treatment is administered, the provider must 
secure payment for the service, including the cost of the product 
dispensed (which the provider had to pay up front with its own funds). 
In this context, the provider has a strong interest in utilizing drugs 
that are widely covered by insurance, particularly by the major 
national commercial health insurers and significant regional insurers 
active in its area. If a drug product is not widely covered, such that 
there is a risk that coverage might be denied, and providers thus would 
be burdened with a potential financial loss for what they paid for the 
product, providers are much less likely to purchase that product--a 
response that is in line with the providers' economic interests (to be 
reimbursed).

    51. Many of the facilities administering infusion services of the 
type at issue here are physician-owned. Thus, the physicians themselves 
have both prescribing authority and a strong financial incentive to 
avoid products that are not widely covered.

    52. Commercial insurers typically publish medical policies 
enumerating the drug products they will cover under the medical benefit 
and the terms under which they will do so. For example, medical 
policies may exclude drugs from coverage, or they may dictate 
restrictions on use. Drug manufacturers compete, usually with rebates 
or other price concessions, to obtain coverage under insurer medical 
policies and to have either fewer restrictions on reimbursement than 
their competitors--or, at a minimum, to achieve ``parity'' whereby the 
competing products have the same restrictions on reimbursement and the 
patient and/or doctor can choose between them. Securing at least parity 
placement is critical, especially for new products seeking to gain 
traction in the marketplace, and particularly with large insurers, 
which have tens of millions of covered patients.

          G. The Importance of Access at the Provider Level

    53. As discussed above, providers (hospitals, clinics, etc.) are 
the market actors that actually purchase infliximab for use with their 
infusion services for patients. J&J's agreements and conduct have the 
effect of foreclosing this essential source of distribution.

    54. Providers do not want to risk being unable to secure 
reimbursement for any drug used to treat a patient after having already 
paid for the product. Because it can be costly to monitor coverage 
status across myriad insurers and implement procedures to match product 
use to a patient's coverage, gaps in reimbursement policies give ``buy 
and bill'' provider accounts reasons to stock only products with 
universal (or near-universal) coverage. Here, due to J&J's 
anticompetitive contracts at the insurer level, J&J has succeeded in 
preventing biosimilar competitors from achieving the same status.

                       J&J'S EXCLUSIONARY SCHEME

    55. Not content with its nearly 2 full decades of exclusivity with 
Remicade, and the billions of dollars of profits that such exclusivity 
enabled, J&J hatched a multifaceted scheme to ensure that biosimilars 
would never become viable competitors--a scheme embodied, at least in 
part, in its ``Biosimilar Readiness Plan.'' J&J revealed the existence 
of the plan, and at least some specifics thereof, during a recent 
investor call and presentation.\14\ And a J&J consultant bragged at a 
recent health conference that his firm helped design the plan to 
realize J&J's goal of ensuring that biosimilars never gain a foothold.
---------------------------------------------------------------------------
    \14\ Johnson & Johnson, Q3 2016 Results Earnings Call Transcript 
(Oct. 14, 2016), available at https://seekingalpha.com/search/
transcripts?term=johnson+%26+Johnson+biosimilar.

    56. J&J's conduct has not gone unnoticed in the industry. For 
example, an analyst at a prominent securities firm (Bernstein Research) 
recently summarized key aspects of J&J's scheme, observing that J&J 
has: (a) ``negotiated with [insurers]'' and set up ``exclusive 
contracts . . . in nearly half the market,'' thereby making providers 
unwilling to purchase Inflectra; (b) ``offered up deeper discounts to 
large independent infusion centers [i.e., major providers], which are 
more economically sensitive''; and (c) ``bundled several drugs and 
medical devices [together] for larger hospitals.'' \15\ The analyst 
also noted that a key to J&J's strategy was the ``long `tail' of 
[patients] remaining on the brand'' \16\--the incontestable demand--
which gives J&J leverage to extract commitments from insurers not to 
cover Inflectra.\17\ Another industry observer, commenting on the 
Bernstein survey, noted that J&J's ``fail first'' requirements with 
insurers ``force hospitals and clinics to buy Remicade.'' The observer 
also noted that:
---------------------------------------------------------------------------
    \15\ Aaron Gal, Biosimilars: So, Why Has Remicade Biosimilar Not 
Gotten Much Traction in the U.S., Bernstein Research, at 1 (July 20, 
2017).
    \16\ Id.
    \17\  While the Bernstein survey suggests that Pfizer has offered 
only a `` `low single digit' discount off of the ASP'' of Inflectra, 
that is not accurate. As set forth herein, Pfizer has offered Inflectra 
at a significantdiscount (to list price as well as ASP), but continues 
to be foreclosed by J&J's anticompetitive contracts. J&J, meanwhile, 
has raised the price of Remicade since Inflectra's entry. The Bernstein 
survey also speculates that with the entry of a third biosimilar in 
mid-2019, ``we would likely [sic] see one of the biosimilars crossing 
the Rubicon and offering the required discounts.'' Gal, supra note 15, 
at 1. However, as set forth herein, J&J's exclusive contracts and 
bundling practices foreclose all new biosimilar entrants, including 
Pfizer, from competing with Remicade on price and, if not stopped, will 
allow J&J to continue to maintain the monopoly power it currently 
exercises with Remicade.

        J&J has had yet another advantage--an ability and willingness 
        to bundle different medicines as part of a package deal. By 
        offering discounts and rebates for several drugs, J&J can 
        secure contracts and crowd out rivals. And discounts are also 
        appealing to physicians who run their own infusion centers.\18\
---------------------------------------------------------------------------
    \18\ Ed Silverman, J&J Now Has Two Competitors for A Pricey 
Blockbuster. Will That Finally Drive Down Prices?, Stat News (July 25, 
2017), https://www.statnews.com/pharmalot/2017/07/25/merck-samsung-
biosimilar-pfizer-johnson/.

---------------------------------------------------------------------------
    57. J&J's scheme is set forth in more detail below:

          A.  J&J Bars Access to Insurer Reimbursement Through Improper 
Exclusive Contracts and Anticompetitive Bundling Practices

                1.  J&J's Exclusive Contracts with Health Insurers

    58. A centerpiece of J&J's strategy to block competition from 
biosimilars has been to secure contractual commitments from commercial 
insurance companies to exclude biosimilars from coverage under their 
plans, making Remicade the exclusive infliximab available to patients 
covered by those plans. Such contractual commitments have taken various 
forms. Some insurers have entered into contracts with J&J that required 
them simply to exclude biosimilars from their medical policies and/or 
drug formularies altogether. Other J&J contracts have imposed a 
spurious requirement that the biosimilar could be reimbursed only after 
a patient first tried and failed on Remicade (the ``fail first'' 
requirement), which virtually ensures that the biosimilar will never be 
prescribed and never be reimbursed. If a patient fails on Remicade, it 
would defy sound medical judgment for a physician to switch to the 
therapeutically equivalent biosimilar, which works in exactly the same 
way, rather than another therapy, to which a patient may potentially 
respond differently.\19\ Regardless of their specific form, these 
contracts all had the same effect--to exclude biosimilars from coverage 
and (as one analyst recently confirmed) grant an ``exclusive'' to 
Remicade.\20\
---------------------------------------------------------------------------
    \19\ The notion that attempting treatment with a biosimilar after 
its reference listed drug has first failed would defy medical judgment 
recently has been reinforced in the European League Against Rheumatism 
rheumatoid arthritis management recommendations. In those 
recommendations, ``[t]he Task Force reiterated its position that if a 
TNF-inhibitor fails, another TNF-inhibitor--but not a biosimilar of the 
same molecule!--can be as effective as changing the mode of action.'' 
Smolen, J.S., et al., EULAR Recommendations for the Management of 
Rheumatoid Arthritis with Synthetic and Biological Disease-Modifying 
Antirheumatic Drugs: 2016 Update, Annals of the Rheumatic Diseases 
2017:0:1-18 (Mar. 6, 2017).
    \20\ Gal, supra note 15, at 1.

    59. J&J has induced most major health insurers, covering at least 
70 percent of commercially insured patients in the United States, to 
adopt these improper contractual exclusivity restrictions and to impose 
outright bans on Inflectra's coverage or so-called ``fail first'' 
requirements. These insurers include (in decreasing order of patients 
---------------------------------------------------------------------------
covered):

    National insurers:

    (a)  UnitedHealthcare: UnitedHealthcare adopted the ``fail first'' 
requirement. United Healthcare has approximately 30.6 million covered 
commercial medical patients across all 50 states.

    (b)  Anthem: Anthem excluded Inflectra from coverage altogether. 
Anthem has approximately 30.4 million covered commercial medical 
patients concentrated in 14 states.

    (c)  Aetna: Aetna adopted a complex set of indication specific 
conditions which operate in practice as ``fail first'' requirements. 
Aetna has approximately 17.9 million covered commercial medical 
patients in all or nearly all states and territories in the United 
States.

    (d)  Cigna: Cigna adopted the ``fail first'' requirement. Cigna has 
approximately 13 million covered commercial medical patients across all 
50 states.

    Regional insurers:

    (a)  HealthNet (Centene): HealthNet adopted a complex set of 
indication specific conditions which operate in practice as ``fail 
first'' requirements. HealthNet (as part of its acquisition by Centene) 
has approximately 12 million covered commercial medical patients 
concentrated in 28 states.

    (b)  CareFirst/Blue Cross Blue Shield: CareFirst adopted the ``fail 
first'' requirement. Indeed, CareFirst agreed with J&J that Inflectra 
would be non-preferred, meaning it cannot be reimbursed unless there 
are ``clinical circumstances that would exclude the use of . . . 
preferred products,'' including Remicade. CareFirst has approximately 
3.2 million covered commercial medical patients principally found in 
Maryland, Virginia, and the District of Columbia.

    (c)  Blue Cross Blue Shield of North Carolina: BCBS of North 
Carolina adopted the ``fail first'' requirement. BCBS of North Carolina 
has approximately 2.7 million covered commercial medical patients 
concentrated in North Carolina.

    (d)  Blue Cross Blue Shield of Tennessee: BCBS of Tennessee adopted 
the ``fail first'' requirement. BCBS of Tennessee has approximately 1.6 
million covered commercial medical patients concentrated in Tennessee.

    (e)  Blue Cross Blue Shield of Louisiana: BCBS of Louisiana adopted 
the ``fail first'' requirement. BCBS of Louisiana has approximately 1.6 
million covered commercial medical patients principally concentrated in 
Louisiana.

    (f)  Excellus Blue Cross Blue Shield: Excellus BCBS adopted the 
``fail first'' requirement. Excellus has approximately 1.2 million 
covered commercial medical patients concentrated in New York.

    (g)  Independence Blue Cross: Independence Blue Cross adopted the 
``fail first'' requirement. Independence Blue Cross is the leading 
health insurer in Philadelphia.

These contracts alone affect approximately 114 million covered 
commercial medical patients of the over approximately 214 million 
patients covered by commercial medical insurance in the United States. 
Pfizer has reason to believe there are more.

    60. While exclusive contracts can--in certain circumstances--be 
perfectly appropriate, the exclusivity provisions described in 
Paragraphs 8, 9, and 58 serve no legitimate or procompetitive purpose 
and were not earned through simple price competition. After Inflectra's 
FDA approval in April 2016, and before J&J implemented its exclusionary 
contracts, health insurers undertook reviews to determine whether there 
was a medical reason not to reimburse Inflectra or to disfavor it 
relative to other therapies. Following these reviews, several major 
health insurance companies--including at least Aetna, Anthem, and 
UnitedHealthcare-- classified Inflectra at parity with Remicade. This 
confirmed that there was no medical reason justifying a restrictive 
reimbursement policy toward Inflectra. It also meant that, for the time 
being, Inflectra would be reimbursed without restriction. As a result, 
the stage was set for Inflectra to begin competing head-to-head with 
Remicade on a level playing field--and for patients to begin receiving 
the benefits of greater choice and lower prices.

    61. But this initial state of affairs was short lived. As a result 
of J&J's anticompetitive conduct, insurers began to reverse course and 
restrict coverage of Inflectra.

    62. For example, in October 2016, UnitedHealthcare, the nation's 
largest health insurer, with over 30 million covered commercial medical 
patients, published an update to its medical and site of care policies 
classifying Inflectra at parity with Remicade for the approved 
indications (with an effective date of November 1, 2016). This meant 
that, for UnitedHealthcare, Inflectra would be reimbursed freely and 
would not be disfavored relative to Remicade. Just weeks later, 
however, UnitedHealthcare reversed course. UnitedHealthcare classified 
Remicade as its ``preferred'' product, and instructed that Inflectra 
would be eligible for reimbursement only in circumstances so limited as 
to be practically non-existent. Under UnitedHealthcare's new policy, 
Inflectra could be reimbursed only where the following conditions are 
met: (a) the patient must show a minimal clinical response, or an 
intolerance or adverse reaction, to Remicade; (b) the physician must 
attest that Inflectra would not lead to the same adverse responses; and 
(c) the patient must show no loss of favorable response in established 
maintenance therapy with Remicade, and must not have developed 
neutralizing antibodies to any infliximab biosimilar product that has 
made the therapy less effective. As a practical matter, this meant that 
Inflectra would not be reimbursed for UnitedHealthcare's more than 30 
million commercial medical members, and that Remicade would be the 
exclusive infliximab with UnitedHealthcare--despite the lack of any 
medical basis for denying those members access to a lower-priced 
alternative to Remicade.

    63. UnitedHealthcare's reversal, of course, did not happen by 
chance. J&J induced UnitedHealthcare to enter into an exclusive deal by 
threatening to penalize UnitedHealthcare with the loss of significant 
rebates unless UnitedHealthcare agreed to deny coverage of Inflectra.

    64. J&J has employed the same approach to secure exclusive deals 
with most or all of the major insurers identified above. In most cases 
these coercive biosimilar-exclusion contracts were the only 
economically viable option for insurers--as adopting any alternative 
would require the insurer to incur a substantial penalty (i.e., 
foregone rebates to existing Remicade patients) that could not be 
offset by the per-unit cost savings available on the number of patients 
likely to use the biosimilar, at least in the near term.

             2. J&J's Bundling Tactics with Health Insurers

    65. J&J's threatened penalties are effective because they leverage 
the large base of existing patients already stabilized on Remicade. 
Given that J&J has offered the only infliximab option in the United 
States for nearly two decades, its base of existing Remicade patients 
is substantial, amounting to hundreds of thousands of patients across 
the country. And, in part driven by J&J's marketing efforts to secure 
this outcome, existing Remicade patients are likely to stay on 
Remicade. Thus, the demand for Remicade associated with this existing 
base of patients is, as a practical and economic matter, incontestable. 
This is so despite the fact that switching is within the scope of FDA's 
approval for use of biosimilars and thus appropriate when medically 
directed--something Pfizer discusses with clients. The situation is 
different for new patients who may be candidates for infliximab. In 
light of this, Pfizer has focused, among other things, on competing for 
a substantial share of new patient starts (the ``contestable'' demand) 
by pricing Inflectra competitively with both insurers and providers on 
a unit-for-unit basis. The fact that Inflectra's ASP is lower than 
Remicade's underscores the cost savings it offers.

    66. By threatening to withhold attractive rebates on all Remicade 
prescriptions-- including those for existing patients as well as new 
ones--unless an insurer agrees to exclusivity, J&J is able to leverage 
the incontestable demand for Remicade to exclude competition for the 
contestable demand, i.e., it bundles the contestable and incontestable 
demand. Even if Pfizer offers a significantly lower price for Inflectra 
unit-for-unit, as it has done, insurers will agree to J&J's exclusive 
deals to avoid losing rebates on the substantial base of existing 
Remicade patients who are not likely to switch to Inflectra despite the 
presence of the lower-priced biosimilar. A recent article by two Yale 
Medical School professors in the Journal of the American Medical 
Association illustrates how the kind of leverage J&J has over existing, 
stable Remicade patients allows it to extract commitments to exclude 
the biosimilar:

        If a biosimilar manufacturer intends to upend the preferred 
        position of the brand by offering a substantial price discount 
        to the [insurer], the branded manufacturer can respond by 
        withdrawing the rebate on the [branded] biologic, creating a 
        ``rebate trap.'' For any patient continuing the [branded] 
        biologic, a payer's cost for that patient will double once the 
        rebate is withdrawn. . . . Even in [an] optimistic scenario, in 
        which the price of the biosimilar is 60 percent less than the 
        price of the brand after rebates and discounts, if the payer is 
        only able to convert 50 percent of its patient users to the 
        biosimilar [because existing patients will tend to stay on the 
        original branded product], the rebate trap ensures that payer 
        total costs actually increase relative to costs prior to 
        biosimilar availability.

                              *    *    *

        To avoid the rebate trap, any strategy to reduce spending on 
        biologics through adoption of biosimilars requires a near-
        complete switch of patient users from the branded biologic to 
        the biosimilar. However, for many chronic diseases, the 
        proportion of patients new to a given biological therapy is 
        less than 20 percent of the total patients taking that drug in 
        a given year. The remainder represents a stable base of 
        patients whose disease is well-maintained while they are using 
        current therapy and thus are unlikely to switch [to the 
        biosimilar].\21\
---------------------------------------------------------------------------
    \21\ Aaron Hakim and Joseph S. Ross, ``Obstacles to the Adoption of 
Biosimilars for Chronic Diseases,'' Journal of the American Medical 
Association (May 1, 2017), available at http://jamanetwork.com/
journals/jama/article-abstract/2625049 (emphasis added).

    67. J&J has further insulated its contracts with insurers from 
competition by bundling rebates for Remicade with rebates on other 
products in return for commitments not to cover Inflectra. J&J made it 
no secret that it would leverage other products as part of its 
``Biosimilar Readiness Plan.'' As J&J's Worldwide Chair for 
Pharmaceuticals made clear on a recent earnings call, ``We are fully 
prepared to execute our focused biosimilar readiness plan,'' including 
``developing innovative contracts . . . [to] utilize the full breadth 
of our portfolio.'' \22\ The ``full breadth of [J&J's] portfolio'' 
includes several drugs for which Pfizer does not offer any directly 
competing alternative. These include drugs such as Simponi (used for 
rheumatoid arthritis, psoriatic arthritis, ankylosingspondylitis, and 
ulcerative colitis), Simponi Aria (used for rheumatoid arthritis), and 
Stelara (used for plaque psoriasis, psoriatic arthritis, and Crohn's 
disease). These products are widely used, with Simponi/Simponi Aria 
generating for J&J approximately $1.7 billion in 2016 and Stelara 
generating for J&J approximately $3.2 billion in 2016. J&J has 
threatened insurers with the loss of rebates on these other drugs, as 
well as Remicade, if they do not agree to exclude Inflectra from 
coverage.
---------------------------------------------------------------------------
    \22\ Johnson & Johnson, Q3 2016 Results Earnings Call Transcript 
(Oct. 14, 2016), available at https://seekingalpha.com/search/
transcripts?term=johnson+%26+Johnson+biosimilar.

    68. J&J's multi-product bundling, along with its bundling of 
contestable demand (i.e., new patients) and incontestable demand (i.e., 
existing Remicade patients), have amplified the anticompetitive effects 
of J&J's exclusive contracts, and made the exclusivity provided by 
those contracts even more durable. Insurers have made it clear to 
Pfizer that its net cost for Inflectra would need to be low enough to 
offset the loss of J&J rebates. But, because of the combined effect of 
these bundles, Pfizer cannot offset the financial penalties that J&J 
threatens to impose on insurers who do not agree to exclusivity. As a 
result, Pfizer is economically prohibited from competing for coverage 
by the major insurers--even when their exclusive contracts with J&J 
expire. J&J can use the same bundling strategies to ensure continuation 
---------------------------------------------------------------------------
of the exclusionary pattern.

          B.  J&J's Improper Insurer-Level Contracts Deter Hospitals 
and Clinics from Purchasing Inflectra, Thus Amplifying Foreclosure

    69. Providers are unwilling to stock a drug product where there is 
significant uncertainty about whether it will be reimbursed by health 
insurers; because they administer infliximab onsite, providers must 
expend funds for the product in the first instance, then seek 
reimbursement after providing treatment. The provider has theoretical 
recourse against the patient where coverage is denied, but the prospect 
of securing payment in full from the patient is bleak, especially for 
drugs as costly as Remicade. As a result, where a significant portion 
of a provider's patients are insured by plans that have agreed to 
exclude Inflectra--pursuant to the types of contracts described above--
the provider is unlikely to offer Inflectra for any of its patients, to 
avoid being caught with no reimbursement.

    70. As a recent article in Bloomberg stated:

        Ascension Health, a nearly 23,000-bed nonprofit hospital system 
        based in St. Louis, spends $55 million a year on Remicade, more 
        than any other drug. Using Inflectra, part of a new class of 
        medicines called biosimilars, would save it at least $10 
        million annually, according to Ascension's chief pharmacist, 
        Roy Guharoy. He met with Pfizer and planned to integrate 
        Inflectra into care more often until learning that insurers 
        preferred to stay with Remicade. ``This we did not expect,'' 
        Guharoy said. ``If the insurance companies force us to use the 
        branded product, of course our hands are tied.'' \23\
---------------------------------------------------------------------------
    \23\ Jared S. Hopkins, What's Harder Than Making Copycat Biotech 
Drugs? Selling Them, Bloomberg (Aug. 15, 2017).

In short, provider purchases are driven by the coverage stated by 
---------------------------------------------------------------------------
commercial insurers.

    71. Having created reimbursement concerns through its exclusionary 
contracts with health insurers, J&J touts the excluded status of 
Inflectra in its marketing communications, knowing that doing so will 
discourage providers from stocking the new biosimilar. As this brochure 
shows, J&J markets the ``fail first'' requirement as a selling point 
despite the fact that such a provision is medically inappropriate and 
despite FDA's determination that there are no clinically meaningful 
differences between the two products. Thus the brochure touts that 
Remicade is ``Preferred Over Inflectra . . . Inflectra requires trial 
and failure on Remicade prior to [Inflectra] utilization.''

[GRAPHIC(S) NOT AVAILABLE IN TIFF FORMAT]  


    72. Given the widespread gaps in Inflectra's insurance coverage--
caused by J&J--providers using infliximab have overwhelmingly chosen to 
stock only Remicade (which is essentially universally covered given its 
long tenure and dominant position) rather than deal with the risk of 
possible denials of coverage for Inflectra. Thus, providers have 
declined to purchase Inflectra across the board, even for patients 
covered by commercial or government insurance plans that do cover the 
product. The effective foreclosure of biosimilars thereby is expanded 
well beyond the 70 percent of commercially insured patients directly 
foreclosed by J&J's insurer contracts. Indeed, as of September 1, 2017, 
about 90 percent of healthcare provider accounts using infliximab had 
purchased no Inflectra at all.

          C.  J&J Has Further Barred Access Through Exclusionary 
Contracts with Providers

    73. To further amplify Inflectra's foreclosure--even beyond the 
population of patients covered by insurance plans that have agreed to 
J&J's exclusivity terms, and the spillover effect on providers 
discussed above--J&J has imposed exclusionary contracts on providers 
themselves (e.g., clinics, hospitals, etc.).

    74. After Inflectra's introduction, J&J began offering certain 
large providers additional rebates and/or discounts on Remicade, but 
only if the provider committed to buy Remicade for nearly all of its 
infliximab needs. To be eligible for rebates, J&J required providers to 
maintain purchase levels for Remicade at very close to the levels of 
the year before Inflectra's launch--when Remicade was the only 
infliximab option. With about 30 percent of prescriptions in any year 
representing new patients (and a certain percentage of existing 
patients exiting therapy each year), this condition also requires 
providers to use Remicade for new patients if they wish to secure 
payment from J&J, thus bundling contestable and incontestable demand 
for Remicade. Like its insurer-level contracts, these contracts as a 
practical matter make Remicade the exclusive infliximab with the 
participating providers.

    75. J&J has also used multi-product bundling in its provider-level 
contracts. As one analyst reported, ``J&J bundled several drugs and 
medical devices for larger hospitals, making Inflectra less 
economical.'' \24\ Conditioning rebates linked to other J&J products 
upon a promise not to do business with Inflectra only exacerbates the 
exclusionary nature of J&J's contracts.
---------------------------------------------------------------------------
    \24\ Gal, supra note 15, at 1.

    76. Pfizer was and is prepared to negotiate with providers to make 
Inflectra the lower-priced infliximab option on a per-unit basis, and 
has even offered to guarantee that Inflectra would be less expensive 
unit-for-unit than Remicade. But as with insurer contracts, to secure 
the right to deal freely as to Inflectra (i.e., principally as to new 
patients), the providers would lose significant J&J rebates on their 
---------------------------------------------------------------------------
existing Remicade patient bases.

    77. For Pfizer to make up the J&J rebates/discounts that insurers 
and providers would lose on their existing Remicade patients, Pfizer 
would have to price Inflectra below its own average variable cost. This 
is because the lost J&J rebates/discounts are based on the much larger 
base of existing Remicade patients, whereas Pfizer would be serving a 
much smaller group of new patients, at least in the near term.

    78. When the total amount of discounts and rebates that J&J offers 
to insurers and providers under the contracts described herein, 
including multi-product bundle contracts, is attributed to the portion 
of Remicade sales that is contestable by a biosimilar like Inflectra, 
J&J is pricing Remicade below its own average variable cost. As a 
result, biosimilar competition to Remicade is foreclosed.

    79. The combined effect of J&J's multifaceted exclusionary scheme 
has been to foreclose Inflectra from approximately 90 percent of the 
provider account distribution channel essential to connecting Inflectra 
with patients of any kind.

             J&J HAS MONOPOLY POWER IN THE RELEVANT MARKETS

    80. Monopoly power is the ability of a single seller to raise 
prices above the competitive price level without losing significant 
business.

    81. For years before Inflectra's entry, J&J's ASP for Remicade 
increased, yet Remicade did not lose business. Between 2007 and 2017, 
Remicade's ASP increased more than 62 percent. Despite Remicade's price 
hikes, unit sales of Remicade have actually grown 15 percent during the 
period from 2012 to 2016.

    82. Inflectra's introduction has done nothing to erode Remicade's 
monopoly power: Since Inflectra was launched, Remicade's ASP has 
continued to increase without impacting Remicade's market position. Ten 
months after Inflectra was introduced, Remicade still accounts for over 
96 percent of all infliximab sales. Indeed, J&J has confirmed that 
``biosimilar competition'' has had ``very little impact'' on 
Remicade.\25\
---------------------------------------------------------------------------
    \25\ Johnson & Johnson, Q1 2017 Results Earnings Call Transcript 
(Apr. 18, 2017), available at https://seekingalpha.com/search/
transcripts?term=johnson+%26+Johnson+biosimilar.

    83. As noted, infliximab is an infusion-administered TNF-inhibiting 
immunosuppressant with FDA approved indications for rheumatoid 
arthritis, psoriatic arthritis, ankylosing spondylitis, ulcerative 
colitis, Crohn's disease, and plaque psoriasis (together, the 
---------------------------------------------------------------------------
``Relevant Indications'').

    84. The broadest appropriate relevant product market is infusion-
administered drugs whose approved labeling from the FDA (a) encompasses 
one or more of the Relevant Indications, and (b) is without restriction 
for the applicable Relevant Indication, that is to say, the labeling 
does not specify that the drug may be used for the applicable Relevant 
Indication only after the patient has not responded to another therapy 
(the ``Relevant Product Market'').\26\ Remicade enjoys a share of over 
60 percent in the Relevant Product Market, nearly the same share it had 
before Inflectra entered.
---------------------------------------------------------------------------
    \26\ For example, the FDA approved Rituxan for the treatment of 
moderate to severe active rheumatoid arthritis in adults only after 
treatment with at least one other TNF antagonist has been used and did 
not work well enough.

    85. The following infusion-administered therapies have been 
---------------------------------------------------------------------------
approved as unrestricted therapies for the Relevant Indications:

          Rheumatoid Arthritis:

              Remicade (infliximab) (J&J) (TNF-
        inhibitingimmuno-suppressant)

              Simponi Aria (golimumab) (J&J) (TNF-
        inhibiting immuno-suppressant)

              Inflectra (infliximab) (Pfizer) (TNF-
        inhibitingimmuno-suppressant)

              Renflexis (infliximab) (Merck) (TNF-
        inhibitingimmuno-suppressant)

              Orencia IV (abatacept) (Bristol-Myers Squibb) 
        (synthetic recombinant DNA technology immune-suppressant)

              Actemra IV (tocilizumab) (Roche) 
        (interleukin-6 blocker) (IL-6 blocker)

          Psoriatic Arthritis:

              Remicade (infliximab) (J&J) (TNF-
        inhibitingimmuno-suppressant)

              Stelara IV (ustekinumab) (J&J) (human 
        interleukin-12 and -23 antagonist)

              Inflectra (infliximab) (Pfizer) (TNF-
        inhibitingimmuno-suppressant)

              Renflexis (infliximab) (Merck) (TNF-
        inhibitingimmuno-suppressant)

              Orencia IV (abatacept) (Bristol-Myers Squibb) 
        (synthetic recombinant DNA technology immuno-suppressant)

          Ankylosing Spondylitis:

              Remicade (infliximab) (J&J) (TNF-
        inhibitingimmuno-suppressant)

              Inflectra (infliximab) (Pfizer) (TNF-
        inhibitingimmuno-suppressant)

              Renflexis (infliximab) (Merck) (TNF-
        inhibitingimmuno-suppressant)

          Plaque Psoriasis:

              Remicade (infliximab) (J&J) (TNF-
        inhibitingimmuno-suppressant)

              Stelara IV (ustekinumab)(J&J) (human 
        interleukin-12 and -23 antagonist)

              Inflectra (infliximab) (Pfizer) (TNF-
        inhibitingimmuno-suppressant)

              Renflexis (infliximab) (Merck) (TNF-
        inhibitingimmuno-suppressant)

          Crohn's Disease:

              Remicade (infliximab) (J&J) (TNF-
        inhibitingimmuno-suppressant)

              Stelara IV (ustekinumab) (J&J) (human 
        interleukin-12 and -23 antagonist)

              Inflectra (infliximab) (Pfizer) (TNF-
        inhibitingimmuno-suppressant)

              Renflexis (infliximab) (Merck) (TNF-
        inhibitingimmuno-suppressant)

              Entyvio (vedolizumab) (Takeda) (integrin 
        receptor antagonist monoclonal antibody)

          Ulcerative Colitis:

              Remicade (infliximab) (J&J) (TNF-
        inhibitingimmuno-suppressant)

              Inflectra (infliximab) (Pfizer) (TNF-
        inhibitingimmuno-suppressant)

              Renflexis (infliximab) (Merck) (TNF-
        inhibitingimmuno-suppressant)

              Entyvio (vedolizumab) (Takeda) (integrin 
        receptor antagonist monoclonal antibody)

These infusion therapies are referred to collectively as the ``Relevant 
Products.''

    86. Certain non-infusion drugs are also indicated to treat the 
Relevant Indications. None of those drugs, however, is a reasonable 
substitute for the infusion-
administered products. None significantly constrains the prices J&J is 
able to charge for Remicade.

    87. The non-infusion products approved for the Relevant Indications 
include oral medications (e.g., Xeljanz) and self-injectables (e.g., 
Humira, Enbrel). These products are patient-administered. Infusion 
drugs, by contrast, must be delivered by healthcare professionals in a 
clinical setting (e.g., hospitals or infusion centers) during infusion 
sessions that take upwards of two hours.

    88. Physicians are not likely to switch from prescribing their 
patients infliximab to prescribing those non-infusion products in 
response to a small but significant non-transitory change in the price 
of infliximab.

    89. Not only are the infusion and non-infusion treatments different 
kinds of therapies, but they are most often sold to different buyers, 
on different contracts, and are distributed by different means:

          Infliximab is, as described above, sold primarily to 
        hospitals and clinics and is almost never stocked by retail 
        pharmacies (only rarely being stocked by certain specialty 
        pharmacies). After administering the infusion treatments to 
        their patients, the hospitals and clinics seek reimbursement 
        from the patients' insurers or government payers.

          By contrast, non-infusion drugs such as Xeljanz, Humira, and 
        Enbrel are primarily sold to and distributed in the pharmacy 
        channels. Physicians who prescribe these non-infusion drugs 
        generally do not administer the treatments and do not bear 
        financial risk with respect to the drug selected.

          Non-infusion drugs are also typically covered by insurance 
        through a pharmacy benefit plan. These are products that 
        insured patients obtain using their ``pharmacy'' cards. Such 
        drugs are put out for bid periodically by insurers and/or 
        pharmacybenefit managers. The bidding process generally does 
        not even include infusion and other therapies not stocked in a 
        retail pharmacy.

          By contrast, infusion therapies generally are treated as 
        part of the basic medical coverage provided by health insurers. 
        Infusion therapies are thus generally put out for bid 
        separately from self-administered therapies.

    90. Beyond the medical reasons physicians may have for prescribing 
an infusion therapy as opposed to a non-infusion therapy, patients 
exhibit strong preferences for one form of therapy over another. 
Patients with active lifestyles often prefer self-administered 
treatments. Infusion therapy, on the other hand, is often preferred by 
patients with needle aversions, or by patients who prefer to have their 
treatments administered by medical professionals.

    91. In addition, infusion and non-infusion therapies are offered at 
very different price points: On an annual basis, Enbrel and Humira 
(which are self-administered therapies) at list price are at least 
twice as expensive as Remicade (which is an infusion therapy) for 
patients stabilized on them.

    92. Because of these various factors, a small but significant non-
transitory increase in price of infusion therapies would not have a 
meaningful impact on the demand for non-infusion therapies, and vice-
versa.

    93. As noted, the Relevant Product Market includes certain segments 
that qualify themselves as Relevant Markets, in which J&J also 
possesses monopolypower. For example:

    94. Specific-use product markets. Specific-use product markets are 
predicated on infusion-administered therapies for the Relevant 
Indications. A small but significant nontransitory increase in price 
for an infusion product in each of these specific-use product markets 
would not cause substitution to non-infusion medicines approved for the 
same indication. In each category, Remicade has been the dominant 
infusion-administered therapy. The categories are as follows:

          Infusion-administered therapies for Crohn's disease. 
        Remicade accounts for over 70 percent of prescriptions to 
        patients of infusion-based drugs indicated for Crohn's disease.

          Infusion-administered therapies for rheumatoid arthritis. 
        Remicade accounts for nearly 55 percent of prescriptions to 
        patients of infusion-based drugs indicated for rheumatoid 
        arthritis. When combined with the share of its product Simponi 
        Aria, J&J commands an aggregate of nearly 65 percent of 
        prescriptions to patients in this category.

          Infusion-administered therapies for ulcerative colitis. 
        Remicade accounts for nearly 70 percent of prescriptions to 
        patients of infusion-based drugs indicated for ulcerative 
        colitis.

          Infusion-administered therapies for psoriatic arthritis. 
        Remicade accounts for over 95 percent of prescriptions to 
        patients of infusion-based drugs indicated for psoriatic 
        arthritis.

          Infusion-administered therapies for ankylosing spondylitis. 
        Remicade accounts for over 95 percent of prescriptions to 
        patients of infusion-based drugs indicated for ankylosing 
        spondylitis.

          Infusion-administered therapies for plaque psoriasis. 
        Remicade accounts for over 95 percent of prescriptions to 
        patients of infusion-based drugs for plaque psoriasis.

    95. Clinic-based product market. The Relevant Product Market 
encompasses a submarket consisting of sales of the Relevant Products to 
non-hospital clinics (including freestanding clinics and physician 
offices with infusion chairs) that administer infusion therapies to 
patients. Such a submarket is properly treated as a relevant submarket 
among other reasons because J&J is able to price discriminate between 
hospitals and non-hospital clinics. The U.S. antitrust enforcement 
agencies and economists recognize that relevant antitrust product 
markets can be based on categories of customers against whom sellers 
can exercise price discrimination, i.e., differential pricing.\27\ Non-
hospital clinics are subject to successful price discrimination by J&J. 
J&J can and does identify and target clinics for differential pricing. 
There are significant differences in the rebates and discounts J&J 
makes available to non-hospital clinics as compared to hospital 
customers. Moreover, a small but significant non-transitory increase in 
the price of Remicade or other Relevant Products will not induce 
infusion clinics to switch to self-administered therapies. A very 
substantial percentage of provider accounts that purchase infliximab 
are non-hospital clinics.
---------------------------------------------------------------------------
    \27\  See, e.g., U.S. Department of Justice and Federal Trade 
Commission Horizontal Merger Guidelines (2010), Sec. 3.

    96. Product markets for new and existing patients. As described 
above, J&J has a substantial base of existing Remicade patients, the 
substantial majority of whom are not likely to switch to another 
therapy, even a biosimilar, if they have achieved relief with 
Remicade--even in response to a small but significant non-
transitory increase in price for Remicade. By contrast, for new 
patients who are candidates for infusion-administered therapies for the 
Relevant Indications, Inflectra is a reasonable substitute for 
Remicade. Thus, there is a distinct product market for sales of 
Relevant Products to new patients in need of infusion-administered 
therapies for the Relevant Indications. There is also a distinct 
product market for patients already stabilized on Remicade--a market 
dominated by Remicade. As described above, J&J's scheme has bundled its 
control over the latter market (for patients stabilized on Remicade) to 
thwart competition in the former market (for new patients in need of 
---------------------------------------------------------------------------
infusion therapy).

    97. Infliximab product market. After discovery, the data may also 
support an infliximab-only product market. Among other things, J&J has 
been able to raise prices for Remicade consistently without losing 
significant sales to other branded drug products. Both J&J and Pfizer 
consider Remicade and Inflectra to be particularly close substitutes. 
For example, J&J's marketing materials focus on comparisons of price 
and clinical effectiveness between Remicade and infliximab biosimilars, 
and do not reference any other therapies, and its ``Biosimilar 
Readiness Plan'' similarly ignores other therapies, focusing instead on 
the unique competitive threat posed by biosimilars. Inflectra's 
marketing materials likewise focus on Remicade, not on other therapies.

    98. Barriers to entry. Substantial barriers to entry exist to 
developing other infusion-administered drug therapies for the Relevant 
Indications generally, and infusion-administered TNF inhibitors 
specifically. The development of a new therapy requires tens if not 
hundreds of millions of dollars and substantial risk, as any new 
product must survive years of research and development, clinical 
trials, and FDA approval. If left unchecked, J&J's conduct will serve 
as an additional barrier to entry, as potential new entrants will 
recognize that they will be unable to break J&J's ``rebate trap'' and 
thus to profitably enter the Relevant Markets--and consequently will 
not invest the resources necessary to develop biosimilars.

    99. While a second biosimilar to Remicade has been approved--called 
Renflexis, sponsored by Merck and Samsung--the sponsoring firms had to 
overcome just the kind of substantial burdens noted above, and began 
the effort long before J&J commenced its scheme to exclude biosimilar 
competition. J&J itself has expressed confidence in maintaining its 
Remicade dominance despite the potential entry of Renflexisbased on its 
exclusionary contracting strategy. Pfizer has received marketplace 
feedback that Renflexis will face the same access challenges from J&J's 
scheme as Inflectra.

    100. J&J's scheme--including coercive contracts bundling the 
incontestable demand (existing patients) with contestable demand (new 
patients), and promoting the results of its exclusionary insurer-level 
contracts to create uncertainty about Inflectra among providers--has 
led directly, with J&J's active encouragement, to nearly all provider 
accounts that use infliximab declining to purchase Inflectra at all. 
Even if some portion of a provider's patient base may be covered, 
providers are unwilling to risk using Inflectra only to ultimately be 
denied coverage. A single denied claim can cost a provider in excess of 
$4,000, whereas the typical provider savings in product acquisition 
cost for a covered Inflectra claim is $200-300. Because Remicade is 
nearly universally covered, providers have taken the ``safe'' option 
and stocked Remicade over Inflectra, thus increasing the already-
substantial foreclosure caused by J&J's exclusionary contracts. Thus, 
as a practical matter, J&J's scheme has foreclosed Inflectra from 
approximately 90 percent of provider accounts using infliximab, the 
essential channel of distribution for infliximab. And, as noted, in 
terms of sales, Remicade continues to control over 96 percent of 
infliximab unit sales.

    101. Geographic market. The relevant geographic market for the 
Relevant Markets alleged herein is the United States of America and its 
possessions and territories, as these products are marketed and sold on 
a national basis.

J&J's CONDUCT HAS STIFLED COMPETITION IN THE RELEVANT MARKETS, THEREBY 
   MAINTAINING AND ENHANCING ITS MONOPOLY POWER AND INJURING PFIZER 

    102. J&J's scheme has led to the near total foreclosure of 
Inflectra with patients across the country. First, its exclusionary 
contracts with health insurers alone--including with most of the 
largest health insurers in the country--have foreclosed Pfizer's 
ability to compete for at least 70 percent of patients covered by 
commercial health insurance plans in the United States. Second, J&J's 
exclusionary contracts with certain providers have foreclosed Pfizer's 
ability to compete even for patients covered by plans that do provide 
reimbursement for Inflectra. And, as discussed, the reimbursement 
challenges (created by J&J) have led most provider accounts to decline 
to purchase Inflectra at all, with approximately 90 percent of provider 
accounts that use infliximab across the country not stocking Inflectra 
at all. As of September 2017, J&J maintained over 96 percent share of 
infliximab unit sales in the U.S.

    103. Despite vigorous efforts to compete--including offering 
guarantees that Inflectra would be less expensive unit-for-unit than 
Remicade--Pfizer has been foreclosed from gaining a competitive 
foothold as a direct result of J&J's scheme. In the absence of 
Remicade's exclusionary practices, Inflectra's growth in the Relevant 
Markets would be substantially greater than it has been, and would be 
substantially larger in the future. J&J's conduct has deprived Pfizer 
of (a) past profits; (b) future profits; and (c) the value of invested 
capital from unrealized efforts to enter and expand in the Relevant 
Markets. Further, Pfizer's current and prospective customer 
relationships and goodwill have been, and will continue to be, 
impaired. J&J's conduct, if allowed to continue, will also dampen the 
incentives of Pfizer and other biosimilar developers to invest the 
substantial resources needed to bring biosimilars to the market. Thus, 
the aims of the BPCIA will have been thwarted.

    104. J&J's activities have not only harmed Pfizer, they have caused 
substantial harm to the competitive process as well as to government 
payers and to consumers, who have been deprived of the principal 
benefits of competition--more choices and lower prices. The 
anticompetitive effects of J&J's conduct are evident in its pricing of 
Remicade since Inflectra's entry. Despite the fact that Pfizer has 
offered substantial discounts and a lower ASP to compete for business 
with insurers and healthcare providers, J&J has been able to increase 
the price of Remicade without losing any significant share or volume of 
sales to Pfizer (or any other competitor). J&J's prices for Remicade 
have been increasing by every measure. J&J has increased Remicade list 
prices twice since FDA approval of Inflectra. These increases alone 
raised Remicade's list price nearly 9 percent. Remicade's actual ASP 
(which, as noted above, is net of discounts, rebates, and other price 
concessions) has also increased since Inflectra's entry-- negating any 
claim that J&J's rebates qualify as meaningful price competition.

    105. There is no efficiency or cost-reducing justification for 
J&J's coercive and exclusionary insurer- or provider-level contract 
terms. J&J has not achieved improved production costs, or economies of 
scale or scope through its contracting strategies. J&J also has 
achieved no improvements in the Remicade treatment through its 
contracting strategies.

    106. If J&J's conduct is not prohibited, it will be adopted by 
other originator biologics firms aiming to preserve their dominant 
positions. As the first major biosimilar approval, this case will be a 
bellwether for the success of Congress's biosimilars initiative, as 
embodied in the BPCIA.

                           CLAIMS FOR RELIEF

                         FIRST CLAIM FOR RELIEF

                     Violation of 15 U.S.C. Sec. 2

                 Monopolization of All Relevant Markets

    107. Pfizer repeats and realleges Paragraphs 1 through 106 as set 
forth herein.

    108. J&J has monopolized the Relevant Markets in violation of 
Section 2 of the Sherman Act.

    109. J&J has monopoly power in the Relevant Markets.

    110. Through the scheme described above, and other conduct likely 
to be revealed in discovery, J&J has willfully and unlawfully 
maintained and enhanced its monopoly power in violation of Section 2 of 
the Sherman Act. J&J's scheme constitutes exclusionary conduct within 
the meaning of Section 2 of the Sherman Act.

    111. J&J's scheme has stifled competition in the Relevant Markets 
and thwarted Congress's purpose in enacting the BPCIA.

    112. Among other things, given that (a) J&J imposed explicit 
conditions that insurers and providers eliminate (or almost completely 
curtail) their dealings with infliximab biosimilars, and (b) J&J's ASP 
for Remicade has actually increased since the biosimilar entered, J&J's 
pricing is not the clearly predominant means by which competition has 
been foreclosed in the Relevant Markets.

    113. Even if price were deemed to be the clearly predominant means 
by which competition has been foreclosed, when the total amount of 
discounts and rebates that J&J offers to insurers and providers under 
the contracts described herein, including multi-product bundle 
contracts, is attributed to the portion of Remicade sales that is 
contestable by a biosimilar like Inflectra, J&J is pricing Remicade 
below its own average variable cost.

    114. As a result of J&J's conduct, and the harm to competition 
caused by that conduct, Pfizer has suffered substantial and continuing 
injuries.

                        SECOND CLAIM FOR RELIEF

                     Violation of 15 U.S.C. Sec. 2

            Attempted Monopolization of All Relevant Markets

    115. Pfizer repeats and realleges Paragraphs 1 through 114 as set 
forth herein.

    116. J&J has attempted to monopolize the Relevant Markets in 
violation of Section 2 of the Sherman Act.

    117. J&J is violating Section 2 of the Sherman Act by attempting to 
implement the anticompetitive scheme set forth above with the specific 
intent to monopolize the Relevant Markets. J&J's scheme constitutes 
exclusionary conduct within the meaning of Section 2 of the Sherman 
Act.

    118. There is a dangerous probability that J&J will succeed in 
monopolizing the Relevant Markets through its anticompetitive scheme.

119. J&J's scheme has stifled competition in the Relevant Markets and 
thwarted Congress's purpose in enacting the BPCIA.

    120. Among other things, given that (a) J&J imposed explicit 
conditions that insurers and providers eliminate (or almost completely 
curtail) their dealings with infliximab biosimilars, and (b) J&J's ASP 
for Remicade has actually increased since the biosimilar entered, J&J's 
pricing is not the clearly predominant means by which competition is 
dangerously likely to be foreclosed in the Relevant Markets.

    121. Even if price were deemed to be the clearly predominant means 
by which competition is dangerously likely to be foreclosed, when the 
total amount of discounts and rebates that J&J offers to insurers and 
providers under the contracts described herein, including multi-product 
bundle contracts, is attributed to the portion of Remicade sales that 
is contestable by a biosimilar like Inflectra, J&J is pricing Remicade 
below its own average variable cost.

    122. As a result of J&J's conduct, and the harm to competition 
caused by that conduct, Pfizer has suffered substantial and continuing 
injuries.

                         THIRD CLAIM FOR RELIEF

                     Violation of 15 U.S.C. Sec. 14

Sale on Condition to Exclude Inflectra and Other Infliximab Biosimilars 
or Impose a Fail First Requirement and to Force Use of Remicade in All 
                            Relevant Markets

    123. Pfizer repeats and realleges Paragraphs 1 through 122 as set 
forth herein.

    124. J&J has entered into agreements with insurers (which reimburse 
Remicade) and providers (which purchase Remicade), whereby it has 
conditioned the availability of discounts, rebates, and/or other price 
concessions on insurers and/or providers eliminating or drastically 
curtailing their dealings with Inflectra (or any other infliximab 
biosimilar).

    125. J&J's agreements function as exclusive agreements, what are 
for all practical purposes sole-source agreements, the effect of which 
is to foreclose substantially competition from rivals, such as Pfizer, 
in the sale of the infliximab to medical providers, in violation of 
Section 3 of the Clayton Act.

    126. The essence of the J&J-insurer contracts is to pay the 
insurers to exclude biosimilar alternatives from their prescription 
drug or medical benefits coverage, whereby the insurers either deny 
coverage altogether or restrict coverage to only the rarest of 
circumstances. The insurers, as the payers for the treatment, have the 
ability to exclude selected drugs from coverage and as a result, 
patients and providers do not have a practical ability to choose 
Inflectra or other infliximab biosimilars over Remicade where coverage 
is not available. Moreover, because insurers wield power over providers 
with the ability to grant or withhold coverage for treatment, and 
because providers are risk-averse when it comes to buying and stocking 
medications such as infliximab, the providers are effectively compelled 
to stock Remicade exclusively.

    127. The intent and effect of the insurers' performance of these 
contracts is to cause providers to forgo alternatives and to drive all 
treatment sales to J&J. The result of the J&J insurer contracts thus is 
the amplification of foreclosure, such that Inflectra and other 
biosimilars are denied access to approximately 90 percent of provider 
accounts and foreclosed from competition in the Relevant Markets.

    128. Because providers and insurers are the gateway for the 
distribution and sale of the Relevant Products, there are no viable 
alternative means of distribution or sale and substantial foreclosure 
exists. Biosimilar competitors to J&J have no practical alternative 
means of selling infliximab to patients.

    129. These de facto exclusive arrangements are in effect durable 
long-term agreements because the incentives J&J has exploited are not 
likely to change. So long as J&J's contracts remain in place, 
biosimilars will not be able to dent J&J's base of existing patients, 
and the incentives underlying J&J's contracts will remain. No insurer 
can practically walk away from and not continue to perform under the 
J&J agreement due to the above-discussed penalties.

    130. The effect of each such agreement is and has been to 
substantially lessen competition in the Relevant Markets. The aggregate 
impact of such agreements is and has been to substantially lessen 
competition or tend to create a monopoly in the Relevant Markets.

    131. By imposing such conditional contracts, J&J is directly and 
proximately foreclosing Pfizer and other competitors from a substantial 
portion of the Relevant Markets.

    132. J&J's conduct has had anticompetitive effects in the Relevant 
Markets, including, without limitation, the effects described above in 
Paragraphs 102 through 106.

    133. As a result of J&J's conduct, and the harm to competition 
caused by that conduct, Pfizer has suffered substantial and continuing 
injuries.

                        FOURTH CLAIM FOR RELIEF

                     Violation of 15 U.S.C. Sec. 1

        Agreements in Restraint of Trade in All Relevant Markets

    134. Pfizer repeats and realleges Paragraphs 1 through 133 as set 
forth herein.

    135. J&J has entered into agreements with insurers and providers of 
Remicade with the purpose and effect of unreasonably restraining trade 
and commerce in the Relevant Markets.

    136. J&J's solicitation and enforcement of the exclusionary 
contracts described above constitute unlawful agreements, contracts, 
and concerted activity that unreasonably restrain trade in the Relevant 
Markets in violation of Section 1 of the Sherman Act.

    137. J&J's conduct has had anticompetitive effects in the Relevant 
Markets, including, without limitation, the effects described above in 
Paragraphs 102 through 106.

    138. Among other things, given that (a) J&J imposed explicit 
conditions that insurers and providers eliminate (or almost completely 
curtail) their dealings with infliximab biosimilars, and (b) J&J's ASP 
for Remicade has actually increased since the biosimilar entered, J&J's 
pricing is not the clearly predominant means by which competition has 
been foreclosed in the Relevant Markets.

    139. Even if price were deemed to be the clearly predominant means 
by which competition has been foreclosed, when the total amount of 
discounts and rebates that J&J offers to insurers and providers under 
the contracts described herein, including multi-product bundle 
contracts, is attributed to the portion of Remicade sales that is 
contestable by a biosimilar like Inflectra, J&J is pricing Remicade 
below its own average variable cost.

    140. As a result of J&J's conduct, and the harm to competition 
caused by that conduct, Pfizer has suffered substantial and continuing 
injuries.

                           PRAYER FOR RELIEF

    141. WHEREFORE, Pfizer respectfully prays that the Court enter 
judgment against J&J and in favor of Pfizer, as follows:

              a.  Awarding Pfizer money damages, trebled pursuant to 
        law, in an amount in excess of $150,000.00 (exclusive of 
        interest and costs);

              b.  Awarding Pfizer the costs of the lawsuit, including 
        its reasonable attorneys' fees and court costs;

              c.  Declaring J&J's conduct unlawful and in violation of 
        the above-
        referenced statutes;

              d.  Entering appropriate preliminary and permanent 
        injunctive relief barring J&J from continuing to undertake its 
        anticompetitive scheme, including its exclusionary contracts; 
        and

              e.  Ordering such other and further relief as the Court 
        may deem just, proper, and equitable.

                          JURY TRIAL DEMANDED

    142.  Pfizer demands a trial by jury for all issues triable by 
jury.

Dated:  September 20, 2017 .        Respectfully submitted,
Philadelphia, PA

                                    Robert Fiebach, Esq. (PA 02812)
                                    Peter M. Ryan, Esq. (PA 81816)
                                    Cozen O' Connor
                                    One Liberty Place
                                    1650 Market Street, Suite 2800
                                    Philadelphia, PA 19103
                                    Tel: +1 215 665 4166
                                    Fax: +1 215 665 2013
                                    [email protected]
                                    [email protected]

                                    Robert A. Milne, Esq. (Pro Hac Vice 
                                    forthcoming)
                                    Michael J. Gallagher, Esq. (Pro Hac 
                                    Vice forthcoming)
                                    Bryan D. Gant, Esq. (Pro Hac Vice 
                                    forthcoming)
                                    White & Case LLP
                                    1221 Avenue of the Americas
                                    New York, NY 10025-1095
                                    Tel: (212) 819-8200
                                    Fax: (212) 354-8113
                                    [email protected]
                                    [email protected]
                                    [email protected]

                                    Elliott E. Dionisio, Esq. (Pro Hac 
                                    Vice forthcoming)
                                    White & Case LLP
                                    555 S. Flower Street, Suite 2700
                                    Los Angeles, CA 90071 2433
                                    Tel: (213) 620-7700
                                    Fax: (213) 452-2329
                                    [email protected]

                                    Counsel for Pfizer Inc.

                                 ______
                                 
           Prepared Statement of Olivier Brandicourt, M.D., 
                    Chief Executive Officer, Sanofi
    Chairman Grassley, Ranking Member Wyden, and members of the 
committee, thank you for the opportunity to appear before the Senate 
Committee on Finance to discuss pharmaceutical pricing, affordability, 
and patient access in the United States. I am Dr. Olivier Brandicourt, 
the chief executive officer of Sanofi.

    At Sanofi, we work passionately every day to understand and address 
the health care needs of patients around the world. We are dedicated to 
solving patients' most serious health challenges in numerous 
therapeutic areas, including diabetes, cardiovascular disease, 
immunology, oncology, multiple sclerosis (MS), rare diseases, and rare 
blood disorders. We are also devoted to preventing diseases through the 
research, development, and delivery of vaccines. And we contribute to 
improving the health of people around the world through our broad 
portfolio of consumer health products.

    Sanofi's U.S. subsidiaries have a rich history in the United States 
dating back over 100 years. We currently employ more than 13,000 
professionals across the United States in a broad range of critical 
roles, including business operations, research and development, and 
manufacturing, with our most significant presence in Massachusetts, 
where we are the largest employer in the life sciences industry, and 
major centers of operation in New Jersey, Pennsylvania, and Tennessee.

    Last year, Sanofi spent almost $7 billion on research and 
development, an increase of approximately 7 percent from 2017, which 
reflects our commitment to bringing better therapies to patients. 
Sanofi plans to maintain this level of R&D investment through 2021, and 
our R&D pipeline now contains 81 projects, including 33 new molecular 
entities in clinical development, and 35 projects that are in Phase III 
or have been submitted to regulatory authorities. This investment means 
that Sanofi potentially will seek approval for nine new medications in 
the next three years, primarily in therapeutic areas where Sanofi sees 
the greatest nexus between our expertise and patient need: diabetes, 
vaccines, oncology, immunology, rare diseases, and rare blood 
disorders.

    Our work in R&D includes more than a dozen compounds for the 
treatment of various kinds of cancers, and we are employing cutting-
edge approaches in an effort to make significant advances for patients. 
Our research includes potential treatments to help the body's own 
immune system fight cancer, and antibody drug conjugates that we 
believe can deliver cytotoxic drugs to tumors while sparing normal 
tissue. Earlier this month, we announced successful results with one 
such candidate in a mid-stage trial in lung cancer, and we intend to 
initiate a pivotal study later this year.
                      i. rising costs for patients
    While the research and development landscape has fundamentally 
changed, the landscape in which patients access medications has also 
fundamentally changed, and not for the better. Affordability of 
medicines is a real and growing challenge for too many Americans. We 
understand the anger of patients who cannot afford the medicines they 
or their loved ones need due to rising out-of-pocket drug costs.

    There is no single root cause to the problem of rising patient out-
of-pocket costs, and in order to develop meaningful solutions for 
patients, it is critical to take a comprehensive look at what is 
driving rising costs for patients. Given the number of factors that 
contribute to determining out-of-pocket costs for patients, every part 
of the supply chain, including manufacturers, has a role to play in 
solving this problem.

    We want everyone--including patients, providers, payers, pharmacy 
benefit managers (PBMs), policy makers, and regulators--to understand 
why we set prices as we do, and to reaffirm our commitment to our core 
principles of access, affordability and innovation. An important 
component of pricing includes the intersection between the list prices 
of our medicines, the net prices we actually receive after accounting 
for all rebates and other discounts, and out-of-pocket costs.

    While list prices often receive the most attention, they reflect 
the initial price we set for our medicines. They are not the amount 
Sanofi receives nor the prices typically paid by government and 
commercial insurers, employers, or PBMs. Under the current system, 
players within the supply chain--including PBMs, plans, wholesalers, 
distributors, and group purchasing organizations--receive either 
rebates and/or fees based on a percentage of the list price. Their 
economic incentives are therefore directly linked to the list price. 
And as long as the net price grows at a predictable rate, the greater 
the list price, the greater the economic returns for many players in 
the supply chain. Manufacturers, in turn, must account for anticipated 
rebates and other discounts when setting their list price.

    Thus, list price is the starting point for negotiations with 
payers, and it is often the basis for patient out-of-pocket costs. But 
focusing solely on the list price does not tell the whole story. In the 
current system, manufacturers pay significant rebates as a percentage 
of the list price to both government and private payers, as well as 
other intermediaries, in an effort to improve access for patients. In 
2018, 55 percent of Sanofi's gross sales were given back to payers as 
rebates, including $4.5 billion in mandatory rebates to government 
payers and $7.3 billion in discretionary rebates. As described later in 
my testimony, due to these rebates, the average aggregate net price of 
our products, including our insulin products, actually has declined 
over the last number of years.

    Sanofi provides rebates to PBMs and health plans to improve patient 
access to, and affordability for, Sanofi medicines. We want these 
rebates, which lower net prices, to benefit patients. Unfortunately, 
under the current system, savings from rebates are not consistently 
passed through to patients in the form of lower deductibles, co-
payments or coinsurance amounts.

    For some patients, out-of-pocket costs are calculated based on a 
medicine's list price. However, based on variability in plan design, 
the list price alone does not explain patients' increasing 
affordability issues.

     Sanofi and Sanofi Genzyme U.S. Gross to Net 2018 Breakdown * 
     
[GRAPHIC(S) NOT AVAILABLE IN TIFF FORMAT]  


------------------------------------------------------------------------
 
-------------------------------------------------------------------------
* Below are the summarized categories (by type) for various
 transactions:
Mandatory Rebates: Medicaid, VA-DOD, Tricare, 340B, Medicare Coverage
 Gap
Discretionary Rebates: Commercial, Medicare, Managed Medicaid, Medicaid
 Supplemental, GPO, Institutional Discounts
Government Purchasing Organization (GPO) Fees & Coupons: Fees paid for
 administration of Sanofi's agreements with Group Purchasing
 Organizations on behalf of their members and various copay assistance
 programs
DPA Fees: Performance based fees earned by wholesalers for providing
 complete sales information and maintaining targeting inventory rates
Cash Discounts: Trade discounts offered to wholesalers for prompt
 payment of invoices
Sales Returns: Netted with Clawback, Other Corrections/Credit Memos
------------------------------------------------------------------------


    For instance, in some cases, affordability issues are the result of 
changes in health plan designs, such as the increase in the number of 
high deductible health plans. Among those with private health 
insurance, enrollment in high deductible health plans (HDHPs) has 
generally increased since 2010. The design of these plans generally 
requires patients to pay the full list price of medicines during the 
deductible phase of the program, rather than the negotiated drug price 
available when the insurance portion kicks in.

[GRAPHIC(S) NOT AVAILABLE IN TIFF FORMAT]  


    In other cases, affordability issues are caused by changes in 
insurance design which increasingly ask patients to pay higher cost-
sharing for their medicines, even when the price of those medicines has 
stayed relatively flat or has declined for the health plan. For 
example, as noted later in my testimony, the average net price of 
Lantus, our most prescribed insulin, has declined by over 30 percent 
since 2012, while the average out-of-pocket burden for patients with 
commercial insurance and Medicare has increased by approximately 60 
percent over that same period. In this case, not only are discounts 
apparently not being passed on to patients, but patients are in fact 
being asked to pay more when PBMs and health plans are paying less for 
the medicine. This situation defies logic and should not happen.

    Increasing out-of-pocket costs also can result from changes to 
prescription drug formularies, which have a significant impact on the 
amount of out-of-pocket costs a patient will be asked to pay. A recent 
opinion piece in The New York Times \1\ powerfully highlights how 
changes to prescription drug formularies not only can create confusion 
and frustration for providers and patients, but also ultimately 
increase costs for patients when the medicines they need are not 
covered on a formulary's preferred tier.
---------------------------------------------------------------------------
    \1\ See https://www.nytimes.com/2019/01/18/opinion/cost-insurance-
diabetes-insulin.html.

    The impact of the role each of these factors plays in out-of-pocket 
costs for any individual patient is highly variable, thus compounding 
the complexity of this issue. Out-of-pocket costs for a medicine for 
any particular patient depend on a number of factors in addition to 
list price, including: (1) what portion, if any, of a manufacturer's 
rebates a PBM or payer passes through to the patient, (2) the benefit 
design of the patient's health plan, and (3) the level of reimbursement 
negotiated between the patient's plan and the particular pharmacy. Each 
of these factors varies significantly among plans and pharmacies--even 
within the same health insurance company or PBM receiving the same 
---------------------------------------------------------------------------
manufacturer rebate--creating confusion and frustration for patients.

    Given the complexity in the system and number of factors that 
impact out-of-
pocket costs, every part of the health-care system has an obligation to 
work to solve this problem. I am grateful that this Committee--and 
others--are taking a holistic approach to collecting information both 
on what is causing the problem for patients, and also on solutions to 
address patient access and affordability without undermining the 
incentives and rewards for scientific risk-taking and discovery that 
are the hallmark of the United States ecosystem and economy.

    I am here today to share Sanofi's story, the actions we have taken 
to improve patient access and affordability, and our ideas about what 
more can be done.
     ii. sanofi actions to improve patient access and affordability
    As a global health-care leader, Sanofi has a long-standing 
commitment to promoting health-care systems and policies that make our 
treatments accessible and affordable to patients in need. We believe we 
can play an important role in the development of constructive solutions 
that will benefit both patients and the health-care system as a whole. 
I will address some of our ongoing initiatives and recommendations for 
solutions in my testimony.

    Sanofi's ultimate goal, detailed below, is to encourage a 
transition to a value-
driven health-care system that provides incentives for continued 
improvements in patient care while increasing access and affordability. 
Given the complexities of the current system, changes must be 
approached thoughtfully, with a focus on establishing processes that 
will both enable affordable access to treatment and protect innovation 
in an era of potentially transformative scientific advancements.

    Sanofi is--and will continue to be--an industry leader in helping 
to address this challenge. While many factors, including decisions 
affecting patient out-of-pocket spending and insurance coverage, are 
influenced or controlled by others in the health-care system, including 
other manufacturers, we recognize that there are actions we can take to 
help improve access and affordability for patients. For our part, we 
recognize that we must price our medicines transparently and according 
to their value, while at the same time contributing to broader 
solutions that improve patient outcomes and the financial 
sustainability of the U.S. health-care system.

    Policy changes are required across the entire health care system. 
But we are not waiting for systemic change to arrive before taking 
action. Sanofi has adopted a variety of approaches to work within the 
current system to improve access and affordability for patients. 
Whether it has been launching new medicines in multiple sclerosis and 
rheumatoid arthritis at disruptively low prices, limiting price 
increases to an external benchmark of overall medical spending, or 
lowering the net price of a medicine, Sanofi has approached the 
challenge of access and affordability not with words, but with actions.
               iii. sanofi pricing principles and actions
    Two years ago, Sanofi announced our progressive and industry-
leading pricing principles to help stakeholders understand our pricing 
decisions and to advance a more informed discussion of issues related 
to the pricing of medicines.\2\
---------------------------------------------------------------------------
    \2\ See https://www.sanofi.us/-/media/Project/One-Sanofi-Web/
Websites/North-America/Sanofi-US/Home/corporateresponsibility/
Prescription_Medicine_Pricing_2019.pdf.

    These principles include a pledge to keep annual list price 
increases at or below the projected U.S. National Health Expenditure 
(NHE) growth rate, an estimate of medical spending calculated by the 
Centers for Medicare and Medicaid Services (CMS) and often used as a 
measure of healthcare inflation. These principles apply to all of our 
prescription medicines if a pricing decision results in more than a $15 
annual increase in the price of the medication. In addition, we 
committed to making both our average aggregate list and net price 
changes across our portfolio transparent to help illustrate how revenue 
accrues to Sanofi versus other parts of the pharmaceutical supply 
---------------------------------------------------------------------------
chain.

    In 2018, all of our price increases were consistent with our 
policy, as are all pricing actions we have taken in 2019. Across our 
entire portfolio of medicines, the average aggregate list price 
increase was 4.6 percent while the average aggregate net price--that 
is, the actual price paid to Sanofi--declined by 8.0 percent.

    The declining average aggregate net price in 2018 represents the 
third consecutive year the amount that health plans and PBMs pay Sanofi 
for our medicines has declined.

         U.S. Portfolio Annual Average Aggregate Price Changes *
------------------------------------------------------------------------
                          Average Aggregate List   Average Aggregate Net
          Year                    Price                    Price
------------------------------------------------------------------------
2016                     4.0% Increase            2.1% Decrease
------------------------------------------------------------------------
2017                      1.6% Increase           8.4% Decrease
------------------------------------------------------------------------
2018                      4.6% Increase            8.0% Decrease
------------------------------------------------------------------------
* Average aggregate across Sanofi's prescription product portfolio.


    Specific to insulin, the average aggregate net price across all 
Sanofi insulin products has declined over the past four years. For our 
entire insulin portfolio, the average net price is 25 percent lower 
today than it was in 2012.\3\
---------------------------------------------------------------------------
    \3\ Based on internal review of pricing actions and payer 
contracting.

[GRAPHIC(S) NOT AVAILABLE IN TIFF FORMAT]  


    In addition to our pledge to limit price increases in the U.S., 
Sanofi's pricing policy includes a commitment to transparency in how we 
price new medicines coming to the market for the first time. When we 
set the price of a new medicine, we hold ourselves to a rigorous and 
structured process that includes consultation with external 
---------------------------------------------------------------------------
stakeholders and considers four factors:

        (1)  A holistic assessment of value, including (a) clinical 
        value and outcomes, or the benefit the medicine delivers to 
        patients, and how well it works compared to a standard of care; 
        (b) economic value, or how the medicine reduces the need--and 
        therefore costs--of other health care interventions; and (c) 
        social value, or how the medicine contributes to quality of 
        life and productivity. Our assessments rely on a range of 
        internal and external methodologies, including health 
        technology assessment (HTA) approaches and other analyses that 
        help define or quantify value and include patient perspectives 
        and priorities.

        (2)  Similar treatment options available or anticipated at the 
        time of launch in order to understand the competitive landscape 
        within the disease areas in which the medicine may be used.

        (3)  Affordability, including the steps we must take to promote 
        access for patients and contribute to a more sustainable system 
        for payers and health-care delivery systems.

        (4)  Unique factors specific to the medicine at the time of 
        launch. For example, we may need to support ongoing clinical 
        trials to provide additional critical information on the value 
        of the product (e.g., longer-term outcomes studies), implement 
        important regulatory commitments, or develop sophisticated 
        patient support tools that improve care management and help 
        decrease the total cost of care.

    Using this approach, Sanofi has launched a number of highly 
innovative products at prices well below the competition, some even 
before our principles were officially adopted.

          In 2012, Sanofi launched Aubagio ', a medicine 
        used to treat relapsing forms of MS, at a list price more than 
        25 percent below the other approved oral MS medication on the 
        market at the time.

          In 2017, we launched Kevzara ', a second line 
        medication used to treat certain types of rheumatoid arthritis 
        (RA), at a list price 30 percent below other leading treatments 
        for RA. After completing a head to head study against the 
        market-leading anti-TNF, Kevzara was found superior in RA 
        patients.

          In 2017, we launched Dupixent ', the first drug 
        of its kind for moderate to severe atopic dermatitis, 
        specifically within the cost-effectiveness range provided by 
        the Institute for Clinical and Economic Review (ICER) of 
        $37,000, compelling the Chief Medical Officer for a leading PBM 
        to say ``this is how pricing should work.'' While we have 
        concerns about ICER's methodology in many of their drug 
        reviews, our willingness to work with ICER is further 
        demonstration to our commitment to price our medicines based on 
        the value they provide with consideration of input from a 
        third-party analysis.

          In 2018, we launched Admelog ' at the lowest list 
        price of any mealtime insulin.

          In February 2019, Sanofi and Regeneron announced that 
        Praluent ' will be made available at a new reduced 
        U.S. list price. Beginning in early March, new U.S. National 
        Drug Code (NDC) option will be available at approximately 60 
        percent less than the original list price for the drug. This 
        action follows our earlier announcement in March 2018, when 
        Sanofi and Regeneron committed to lowering the U.S. net price 
        for payers in return for reducing burdensome access barriers 
        for appropriate patients.\4\ Sanofi and Regeneron took the 
        additional step of announcing a new NDC to further assist 
        patients, particularly in Part D, who still face cost-sharing 
        linked to the list price, and who were thus not helped by the 
        earlier net price reduction. With the new lower-priced 
        Praluent, most Medicare Part D patients are expected to save as 
        much as $345 per month, depending on their insurance plan.
---------------------------------------------------------------------------
    \4\ See http://www.news.sanofi.us/2018-03-10-Sanofi-and-Regeneron-
announce-plans-to-make-Praluent-R-more-accessible-and-affordable-for-
patients-with-the-greatest-health-risk-and-unmet-need.

    With the right incentives in the system, our approach to setting 
launch prices for these new medicines would have had the effect of 
ensuring affordable access for patients. Unfortunately, because of the 
way the U.S. health care system is currently constructed, our 
experience has shown that pricing medicines at lower list prices has 
failed to result in adequate access or affordability for most patients. 
For instance, since Dupixent was launched, rebates have been required 
in most cases to secure access for patients. Despite the responsible 
list price and subsequent rebates, 8 commercial and 2 Medicaid plans 
nevertheless implemented a step edit requiring patients to try 
immunosuppressant therapy first before using Dupixent. They implemented 
this step edit notwithstanding the fact that immunosuppressant therapy 
is not FDA approved for use in atopic dermatitis and is referenced as a 
worst-case scenario for patients in practice guidelines due to its 
questionable benefit-risk profile.
              iv. sanofi's insulin products: a case study
    We feel a special obligation to address the pressing issues around 
access and affordability of insulin products. In my time as CEO, Sanofi 
has made a concerted effort to improve both system sustainability and 
patient affordability in our approach to our portfolio of insulin 
products, which includes six different products to meet individualized 
patient needs. And it is important to note the evolution and innovation 
of insulin, as we are often asked if anything has changed in the last 
100 years that warrants pricing action.

    Sanofi's groundbreaking discovery of insulin glargine, and its 
development of a novel pre-filled disposable injection pen to deliver 
insulin glargine, have profoundly improved the lives of millions of 
patients living with diabetes in the United States and worldwide. 
Sanofi's insulin glargine drug products are sold under the trade names 
Lantus ', Lantus SoloSTAR ', Toujeo SoloSTAR 
', and Toujeo Max SoloSTAR ', each of which 
represents a significant leap forward in the treatment of diabetes. 
Sanofi has been awarded patents for its innovative technologies on each 
of these products.

    These novel drug products began with Sanofi's discovery of insulin 
glargine. Despite having ``insulin'' in its name, Sanofi's insulin 
glargine is markedly different from prior insulin products, which had a 
relatively short duration of action and required patients to inject 
themselves multiple times a day and wake up at night for injections in 
order to control blood glucose levels. Each injection of prior insulin 
products caused a sharp spike in the patient's insulin levels, which 
could cause symptoms of low blood sugar ranging from shakiness and 
confusion to, in the extreme, coma or death. Injections also had to be 
timed before every meal, disrupting patient's lives, sleep times, and 
ability to eat with friends and family. As such, the consistent goals 
of insulin therapy over the last century have included reducing the 
frequency of insulin administration and flattening the post-
administration peak of insulin in the bloodstream. Prior attempts to 
achieve these goals included cumbersome mechanical pumps that had to be 
worn on the body for constant infusion, and NPH insulin, which had an 
intermediate duration of action but still caused a pronounced peak in 
insulin levels.

    Glargine changed all of that. Sanofi scientists, in a remarkable 
feat of protein engineering, succeeded in fundamentally altering the 
human insulin molecule at the amino acid level, changing its 
pharmacological characteristics to give patients a steady release of 
insulin with just a single daily administration. Unlike anything that 
came before it, glargine forms tiny solid crystals upon injection that 
dissipate over time to provide a flatter, stable, long-lasting effect 
that mimics the flat profile of insulin release from a healthy pancreas 
and reduces the risks caused by low blood sugar. The once-daily 
administration of glargine also proved a significant boon to patient 
lifestyles.

    Insulin is also an excellent example of list prices not reflecting 
the actual prices paid by insurance companies, and out-of-pocket costs 
that continue to rise despite lower net prices. The net price of our 
insulin product Lantus ', for example, has fallen over 30 
percent since 2012; yet, over this same period, average out-of-pocket 
costs for patients with commercial insurance and Medicare--before the 
benefit of any Sanofi financial assistance program--has risen 60 
percent.
               v. sanofi's financial assistance programs
    Our commitment to affordability for patients extends beyond 
responsible launch pricing, limited price increases, and transparency. 
We offer a suite of traditional and innovative patient assistance 
programs to enable appropriate patient access and to help patients 
afford the Sanofi medicines prescribed to them. We publicize our 
programs in a number of ways to ensure patients and providers are aware 
of our offerings, including through advertising online, on television, 
as well as in provider office settings and at pharmacies.

    As noted previously in my testimony, rising out-of-pocket costs for 
patients is a complex problem with many causes. In some cases, access 
issues are linked to lack of insurance. But having insurance is no 
longer a guarantee of affordable care, and Sanofi believes it is also 
critical to address the needs of patients who may be exposed to 
excessive cost-sharing based on insurance plan design or other 
deficiencies in the system.

    Because patient situations are different, we have carefully 
tailored our assistance programs for insulin products to meet a variety 
of patient needs:

          Commercially insured patients qualify for our co-pay 
        assistance program, which reduces the financial burden for 
        insulin products. Through this program, over 90 percent of 
        participating commercially insured patients pay either $10 or 
        $0 per month for their Sanofi-manufactured insulin products. 
        Last year, our co-pay assistance programs for commercially 
        insured patients provided more than 400,000 eligible patients 
        with $342 million in patient savings.

          For diabetes patients who do not qualify for one of our co-
        pay assistance programs, we created the Insulins ValYOU Savings 
        Program in 2018. The purpose of this program is to provide 
        relief for those patients who currently pay high variable 
        retail prices for insulin and do not qualify for other 
        assistance programs. Through this program, eligible individuals 
        can access all Sanofi insulins for $99 per 10 mL vial or $149 
        for a pack of SoloStar pens, approximately a one-month supply 
        of insulin,\5\ at a discount of up to 60 percent discount below 
        the list price, resulting in potential savings of up to $3,000 
        per year. There are no income requirements and the program is 
        available at U.S. pharmacies. Last year (its first year), the 
        program resulted in $6.2 million in patient savings.
---------------------------------------------------------------------------
    \5\ Patients with type 1 diabetes require insulin replacement with 
both long-acting (basal) and mealtime (bolus) insulin. An average adult 
with type 1 diabetes who weighs 70 kg (155 pounds) should be taking 
anywhere from 0.5-1.0 u/kg/day--depending upon activity levels, and 
meal choices. Using the higher daily dose of 1.0 u/kg/day, this patient 
would need a total of 70 units/day of insulin, of which approximately 
half should be mealtime (bolus) insulin and half should be long-acting 
(basal) insulin. For this average patient, one vial of long-acting 
(basal) and one vial of mealtime (bolus) insulin could provide a 
monthly supple of insulin.
    Many patients with type 2 diabetes require long-acting (basal) 
insulin only. Our internal data shows the average daily dose is 
approximately 45 units per day, resulting in a monthly requirement of 
1350 units of long-acting (basal) insulin per month. Lantus SoloSTAR 
' pack contains 1500 units of insulin (5 pens x 300 units 
per pen) and Toujeo SoloSTAR ' pack contains 1350 units of 
insulin (3 pens x 450 units per pen). For the average patient with type 
2 diabetes, the ValYOU Savings Program would meet the monthly insulin 
requirement with one payment of $149. Patients on lower doses of Lantus 
may opt for the 10ml vial, which would meet the monthly insulin 
requirement with one payment of $99.

          For eligible low-income patients, Sanofi offers many of our 
        medicines, including our insulin products, at no charge through 
        its Sanofi Patient Connection patient assistance program. We 
        are proud that, in 2018, more than 93,000 patients participated 
        in the Sanofi Patient Connection program, receiving free 
---------------------------------------------------------------------------
        medicine valued at $508 million.

    While Sanofi alone cannot eliminate the issue of patient 
affordability, no matter how comprehensive or innovative our patient 
assistance programs, we believe that our efforts can make a meaningful 
difference for many patients. We are committed to maintaining these 
programs and raising awareness of these options to the patients who 
need them.
                          vi. policy proposals
    Over the past few years, we have led by example and made decisions 
to help improve access and affordability for patients. I am here today 
to tell you that I know our actions, while well-intentioned, have not 
been enough. I hope we can all agree on market-based policy solutions 
that will incentivize a high-value, sustainable health-care system that 
improves the affordability of innovative medicines in the U.S.

    Based on our experience, targeting list price controls alone will 
not be sufficient to address patient access and affordability. That is 
why the solution to drug pricing must include protections for patients, 
tying responsible pricing to both access and affordability for 
patients.

    There are obviously a variety of ways to accomplish this, and 
Sanofi could support any number of options that align to our core 
principles:

        (1)  The U.S. should continue to maintain a strong ecosystem 
        for innovation. As such, any policy proposals should strictly 
        avoid directly and artificially controlling the price of 
        medicines, either through price controls set by the Federal 
        Government, or worse, outsourcing that decision to foreign 
        governments. Policy proposals that we believe would 
        fundamentally undermine the unique innovation ecosystem of the 
        United States include reference pricing, importation, or price 
        controls set by CMS. Based on our experience, these approaches 
        may be effective at controlling budgets for central payers but 
        come at a steep cost for patients--namely limiting access to 
        innovative treatments. Additionally, given that the U.S. is the 
        world's leader in science and innovation--and the jobs that 
        come with it--these approaches pose additional risks to the 
        U.S. economy and future scientific discovery. Finally, and most 
        importantly, given the differences between systems, these 
        approaches may do little to improve access and affordability 
        for patients.

            As we have experienced, within the current system, 
        declining prices for payers or new treatments priced at 
        responsibly lower list prices are no guarantee that those 
        actions will translate to affordability or access for patients.

        (2)  Changes to the pricing system must be holistic, and the 
        majority of benefits should accrue to patients. As noted 
        previously, simply enacting price controls--either set by a 
        State, Federal, or foreign government--will not solve the 
        problem of access and affordability for patients. We believe 
        system incentives need to change to encourage smaller list 
        price increases, or even list price reductions, by requiring 
        health plans to cover those medicines that meet these standards 
        at an affordable co-pay level and only allow access 
        restrictions consistent with the label and accepted evidence-
        based best clinical practice.

            If policies are enacted that solely target the list price 
        of medicines without these common-sense patient protections, 
        our shared goal of lowering drug costs--for both government and 
        patients while maintaining the engine of innovation in the 
        United States to bring new innovative medicines to patients 
        will not be fully achieved. To appropriately accomplish this 
        objective, Sanofi is willing to trade price for access and 
        affordability and share accountability for offsetting the 
        financial impact on the Medicare programs.

            Sanofi supports and recommends several policy solutions to 
        incentivize responsible pricing behavior. To ensure that these 
        changes do not create a windfall for manufacturers or health 
        plans and PBMs, Sanofi recommends applying these policies only 
        to medicines that satisfy certain limits on price increases. 
        This approach will shift the current incentives in the system 
        to reward ``good'' behavior in a manner that truly helps 
        patients. Several of the solutions outlined below are also 
        priorities for Chairman Grassley, Ranking Member Wyden and 
        other members of this committee and I look forward to the 
        opportunity to work with you on advancing these and other 
        policy initiatives:

            First, reducing out-of-pocket costs for patients is our top 
        priority. As we have experienced, limiting list price of 
        medicines alone is not sufficient to fully solve this problem. 
        Sanofi has identified a number of ways to effectively reduce 
        out-of-pocket costs for consumers and broadly supports 
        tradeoffs between price and access to help patients, including:

             Implementation of the Anti-Kickback Safe Harbor rebate 
        proposed rule in a manner that directly lowers out-of-pocket 
        costs for patients without creating loopholes that would 
        undermine the proposed rule's intent.

             Requiring a portion of the discounts and rebates paid by 
        manufacturers to reduce costs for patients at the pharmacy 
        counter.

             Changing government price reporting rules and the Anti-
        Kickback statute in a manner that would promote value-based 
        contracting.

             Implementing an annual out-of-pocket cap for Medicare 
        beneficiaries.

             Allowing manufacturers to offer co-pay assistance to 
        Medicare beneficiaries.

             Changing or clarifying government price reporting rules 
        to make it easier to reduce list prices on medicines that have 
        been on the market for a long time--namely by (1) making clear 
        that the government pricing metrics for the new, lower list 
        price drug do not have to be averaged with the metrics for 
        older, higher list price drug and (2) permitting a company to 
        treat the new lower price drug as a new product for purposes of 
        Medicaid rebate calculations, which will help to link the 
        rebate liability for the new drug to the new drug's lower price 
        as opposed to the higher price for the old drug.

            Second, Sanofi supports policies that cultivate a highly 
        competitive free market system and rewards the type of 
        entrepreneurial risk-taking necessary to the discovery and 
        development of life-saving new medicines. A key element of that 
        system is a strong and predictable intellectual property 
        system. However, after a reasonable period of time--which I 
        believe is already reflected in U.S. law--generic and 
        biosimilar medicines should quickly enter the market to offer 
        long-term access at lower costs. To help accomplish these 
        goals, Sanofi supports:

             Legislation that promotes competition, such as the 
        CREATES Act, and prohibitions on ``reverse payment'' 
        agreements. While some changes may be needed to avoid 
        unintended consequences, we support moving forward with 
        policies that limit manufacturers' ability to unfairly avoid 
        competition. At Sanofi, we make product supply available to 
        generic and biosimilar manufacturers developing data necessary 
        for FDA applications for their products. We do this in a timely 
        manner and on reasonable terms.

             Increased system-wide transparency, which would improve 
        competition across health care by making relevant information 
        available to patients and policymakers. Providing more 
        information about what is driving costs in the system and how 
        money is flowing through the system will allow for increased 
        competition and better-informed decision making. Policies like 
        the SPIKE Act, which appropriately include a threshold for 
        reporting to incentivize responsible pricing behavior and the 
        C-THRU Act, are potential approaches.
                            vii. conclusion
    I look forward to having a productive conversation about the 
complexities of the current prescription drug pricing system and 
proposals to improve affordable patient access to high quality, 
innovative medications to drive optimal health outcomes.

    Thank you for the invitation to speak with you today and I look 
forward to working with you.

                                 ______
                                 
    Questions Submitted for the Record to Olivier Brandicourt, M.D.
               Questions Submitted by Hon. Chuck Grassley
    Question. The Department of Health and Human Services' proposed 
rule, ``Fraud and Abuse; Removal of Safe Harbor Protection for Rebates 
Involving Prescription Pharmaceuticals and Creation of New Safe Harbor 
Protection for Certain Point-of-Sale Reductions in Price on 
Prescription Pharmaceuticals and Certain Pharmacy Benefit Manager 
Service Fees,'' envisions that drug manufacturers will offer up-front 
discounts rather than the back-end rebates that are now commonly 
provided. Some observers argue that a 1996 court case called into 
question whether manufacturers could offer up-front discounts, 
resulting in today's rebate-based system. I've heard differing opinions 
as to whether the issues related to the initial court case are still 
relevant. If the HHS proposed rule is finalized, can you assure the 
committee that your company will offer up-front discounts? If not, why?

    Answer. As the question notes, one of the practical implications of 
the Proposed Rule is to incentivize a shift from back-end rebate 
payments to up-front discounts that are passed through at the point-of-
service to the patient (at least in part). We understand that some in 
the health care industry have raised concerns that the nation's 
antitrust laws, specifically the Robinson-Patman Act, and long-running 
antitrust litigation involving drug manufacturers, wholesalers, and 
pharmacies could prevent or reduce discounting under a pricing 
structure without rebates. But, the Robinson-Patman Act focuses on 
price discrimination--involving any dimension of price--and it does not 
distinguish between up-front discounts and rebates. In addition, the 
referenced litigation, In re Brand Name Prescription Drugs Antitrust 
Litigation, did not result in any change in the ability of a 
prescription drug manufacturer to offer an up-front discount. 
Consequently, because Sanofi's view is that the antitrust laws apply 
equally to up-front discounts and back-end rebates, we do not believe 
that they present any impediment to offering up-front discounts to 
patients at the point of sale. Sanofi is committed to working with 
other stakeholders to lower patient out-of-pocket costs, and the 
company will carefully review any final rule issued by HHS regarding 
the Anti-Kickback Statute and its safe harbor regulations--with the 
goal of providing point-of-sale discounts to patients in a compliant 
manner to help lower patient out-of-pocket costs.

    Question. Please describe how you expect your company to respond to 
the HHS proposed rule to eliminate safe harbor protection for back-end 
rebates in Medicare Part D that is referenced above if it is finalized. 
Assuming you are confident that antitrust laws do not prevent your 
company from offering up-front discounts, specifically, do you envision 
that your company lowers the list price of a drug to the current after-
rebate net price, offer discounts equal to the current rebate amount, 
or a combination of both?

    Answer. Sanofi is committed to working with other stakeholders to 
lower patient out-of-pocket costs, and the company will carefully 
review any final rule issued by HHS regarding the Anti-Kickback Statute 
and its safe harbor regulations--with the goal of providing point-of-
sale discounts to patients in a compliant manner to help lower patient 
out-of-pocket costs.

    With respect to list price, if (1) the proposed changes to the 
anti-kickback statute safe harbors were codified, and (2) Congress 
implemented similar changes to the commercial insurance market, Sanofi 
would lower the list prices of its prescription medications for 
products in competitive categories for which there is currently a 
material difference between list price and net price on the assumption 
that patient access and affordability would be improved. Sanofi also 
supports policy changes that would de-link other payments in the 
pharmaceutical supply chain from list price.

    We support extending the intent behind the anti-kickback statute 
safe harbor proposed rule to the commercial market so that incentives 
are aligned across the marketplace. Together, we believe these changes 
would facilitate Sanofi's ability to lower our list prices. However, we 
recommend a step-wise approach, implementing changes to the commercial 
market after the safe harbor rule is implemented on January 1, 2020. 
Such an approach would provide an opportunity for stakeholders and the 
government to identify unintended consequences, and address them, prior 
to extending these policies to the commercial market.

    We want to ensure that the new system achieves its goal of 
improving affordability for patients. For instance, CMS should monitor 
and evaluate how the new system affects formulary access, utilization 
management, and patient cost-sharing, particularly with respect to 
medicines with a lower list price. We also have concerns that changes 
to the rebate system may lead to new fees, which simply require 
manufacturers to pay previous rebate values in new ways, rather than 
creating savings for patients.

    Without a better understanding of how these policy changes 
ultimately would affect the competitive marketplace, patient access, 
and affordability, we are unable to quantify the amount of up-front 
discounts or any potential list price reduction.

    Question. To what extent are the back-end rebates your company 
currently offers contingent on the amount of market share realized for 
your drugs as a result of Part D plan formulary placement and other 
techniques?

    Answer. Sanofi negotiates rebates with PBMs and Part D plans to 
secure better formulary position for our products, which in turn 
provides the best possible access and cost sharing for the majority of 
Medicare Part D beneficiaries. When evaluating what level of rebates to 
offer, Sanofi considers the potential business impact of such 
arrangements.

    Question. Please provide a breakdown of percentage of sales that go 
to each payer (including Medicare, Medicaid, private pay, other) and a 
similar percentage by volume of the total number of each drug compared 
to total volume. Please provide this data for the most recent year 
available.

                         Primary Care Products

                                    Percentage of Sales by Payer Channel \1\
----------------------------------------------------------------------------------------------------------------
                                                                      Channel
----------------------------------------------------------------------------------------------------------------
                                                                                   FSS Others
             Product              Commercial  Medicare  Medicaid  Tricare   340B      \2\      Institutional \3\
----------------------------------------------------------------------------------------------------------------
Lantus                                   25%       36%       10%       0%     5%          19%                 4%
----------------------------------------------------------------------------------------------------------------
Toujeo                                   47%       39%        7%       0%     4%           2%                 0%
----------------------------------------------------------------------------------------------------------------
Soliqua 100/33                           77%       15%        3%       0%     3%           1%                 0%
----------------------------------------------------------------------------------------------------------------
Apidra                                   16%        1%       66%       0%     8%           7%                 2%
----------------------------------------------------------------------------------------------------------------
Admelog                                   0%        0%       91%       0%     9%           0%                 0%
----------------------------------------------------------------------------------------------------------------
Multaq                                   24%       57%        2%       0%     3%          12%                 2%
----------------------------------------------------------------------------------------------------------------
Praluent                                 22%       32%        1%       0%     2%           5%               38%
----------------------------------------------------------------------------------------------------------------
\1\ Based on gross sales.
\2\ This category includes the VA, DOD, and other purchases through Sanofi US's Federal Supply Schedule (FSS).
\3\ This category includes Hospital/GPO, Long-Term Care, Outpatient, and Staff Model.


                                      Percentage by Volume by Payer Channel
----------------------------------------------------------------------------------------------------------------
                                                                      Channel
----------------------------------------------------------------------------------------------------------------
             Product               Commercial  Medicare  Medicaid  Tricare   340B   FSS Others    Institutional
----------------------------------------------------------------------------------------------------------------
Lantus                                    25%       36%       10%       0%     5%          19%                4%
----------------------------------------------------------------------------------------------------------------
Toujeo                                    47%       39%        7%       0%     4%           2%                0%
----------------------------------------------------------------------------------------------------------------
Soliqua 100/33                            77%       15%        3%       0%     3%           1%                0%
----------------------------------------------------------------------------------------------------------------
Apidra                                    16%        1%       67%       0%     7%           7%                2%
----------------------------------------------------------------------------------------------------------------
Admelog                                    0%        0%       91%       0%     9%           0%                0%
----------------------------------------------------------------------------------------------------------------
Multaq                                    24%       57%        2%       0%     3%          12%                2%
----------------------------------------------------------------------------------------------------------------
Praluent                                  22%       32%        1%       0%     2%           5%               38%
----------------------------------------------------------------------------------------------------------------

                        Specialty Care Products

                                    Percentage of Sales by Payer Channel \4\
----------------------------------------------------------------------------------------------------------------
                                                                           Channel
----------------------------------------------------------------------------------------------------------------
                                              Commercial/               Medicaid/VA /             Non-Contracted
                  Product                    Managed Care    Medicare    DOD/Tricare    PHS/340B       Sales
----------------------------------------------------------------------------------------------------------------
Cerdelga                                                0%        12%              6%         4%             78%
----------------------------------------------------------------------------------------------------------------
Cerezyme                                                0%        15%             15%        22%             48%
----------------------------------------------------------------------------------------------------------------
Aldurazyme                                              0%         6%             29%        23%             42%
----------------------------------------------------------------------------------------------------------------
Fabrazyme                                               0%        13%             10%        26%             51%
----------------------------------------------------------------------------------------------------------------
Myozyme                                                 0%        18%             15%        31%             36%
----------------------------------------------------------------------------------------------------------------
Thyrogen                                                0%         4%              5%        25%             66%
----------------------------------------------------------------------------------------------------------------
Caprelsa                                                0%         6%             10%         0%             84%
----------------------------------------------------------------------------------------------------------------
Aubagio                                                47%        33%             11%         2%              7%
----------------------------------------------------------------------------------------------------------------
Lemtrada                                                0%        35%             10%        41%             14%
----------------------------------------------------------------------------------------------------------------
Kevzara                                                69%        15%              4%         3%              9%
----------------------------------------------------------------------------------------------------------------
Dupixent                                               75%         9%              6%         3%              7%
----------------------------------------------------------------------------------------------------------------
Eloctate                                                0%         5%             33%        37%             25%
----------------------------------------------------------------------------------------------------------------
Alprolix                                                0%         5%             27%        39%             29%
----------------------------------------------------------------------------------------------------------------
Jevtana                                                 0%        70%              1%        30%              0%
----------------------------------------------------------------------------------------------------------------
Zaltrap                                                 0%         0%              0%         0%            100%
----------------------------------------------------------------------------------------------------------------
Elitek                                                  0%        15%              1%         7%             77%
----------------------------------------------------------------------------------------------------------------
Mozobil                                                 0%        25%              6%        45%             24%
----------------------------------------------------------------------------------------------------------------
Thymoglobulin                                           0%         0%              0%         4%             96%
----------------------------------------------------------------------------------------------------------------
\4\ The data used to derive this information is contracted sales data. Because many of these products are
  purchased through non-contracted sales, Sanofi has a limited view regarding through which channels these
  products are purchased. Percentage by volume by channel results in similar percentages to percentage by sales
  so a separate chart is not provided.


    Question. Do your companies hire consultants or lobbyists to 
promote products at State Medicaid Pharmacy and Therapeutics 
Committees? To whom do you disclose advocacy activities surrounding 
State Medicaid programs, if at all?

    Answer. Sanofi does not hire external consultants or lobbyists to 
advocate for coverage of our products at State Medicaid Pharmacy and 
Therapeutics Committees. Sanofi employees do attend State Medicaid 
Pharmacy and Therapeutics Committees meetings. Relevant advocacy 
activities to support Medicaid access and coverage of our medicines, if 
any, are disclosed to States in accordance with individual State laws.

    Question. Please describe how the costs of patient assistance 
programs are accounted for within your company's financial statements. 
Please also describe the types of market information, such as 
prescribing and use patterns, that your company collects from different 
types of patient assistance programs and patient hub services.

    Answer. Within Sanofi's financial statements, Sanofi includes the 
administrative costs of the company's co-pay assistance programs, other 
point-of-sale programs, and free drug patient assistance program 
(Sanofi Patient Connection) in the ``Selling and general expenses'' 
line item. For co-pay assistance and other point-of-sale programs, 
Sanofi records the pharmacy reimbursement amount paid by the company as 
a reduction in sales. Sanofi records free product provided through 
Sanofi Patient Connection within ``Cost of Sales.'' Sanofi Care North 
America, the 501(c)(3) operating foundation that donates free product 
to Sanofi Patient Connect, records the free goods as a ``Contribution'' 
when received from Sanofi and as a ``Donation'' when donated to Sanofi 
Patient Connection.

    With regard to market information associated with its patient 
assistance programs and hub services, Sanofi generally collects data 
that aids in the efficient administration and operation of these 
programs. For example, the vendors operating Sanofi Patient Connection 
and the hubs collect information provided by patients on enrollment 
forms, including patient and provider demographic information, patient 
insurance information, patient diagnosis, and prescription information 
necessary to evaluate patient program eligibility and/or administer the 
program. (Sanofi does not itself receive patient protected health 
information except in very limited circumstances, such as when a 
patient reaches out to Sanofi directly when they do not agree with 
their patient assistance eligibility determination or when Sanofi 
monitors vendor calls for compliance with company policies and 
procedures.) With respect to Sanofi Patient Connection, Sanofi does not 
use this information for purposes other than administering the patient 
assistance program. With respect to hub services, in addition to using 
this information to administer hub programs, Sanofi may use this data 
to develop market and business insights.

    With respect to Sanofi's point-of-sale patient assistance programs, 
Sanofi also receives anonymized program utilization data, including 
information about patient out-of-pocket costs, the average amounts that 
Sanofi reimburses pharmacies through the program, abandonment rates, 
dispensing pharmacies, and the prescribers writing the prescriptions 
associated with program utilization. This information is used to 
administer the program. Sanofi may also use this data to develop market 
and business insights.

    Question. Please provide a list of all contributions since January 
1, 2014, that your company has made to any tax exempt organizations 
working on issues related to drugs within your product lines, including 
but not limited to patient groups, disease awareness groups, medical or 
professional societies, universities or hospitals, industry 
associations or leagues. For each contribution, please provide the name 
of the organization that received the donation, the date the donation 
was made, the amount of the donation, and a description of the purpose 
of the contribution (i.e., was the contribution for the general fund, a 
specific purpose to a specific program, or continuing medical 
education). Please also note whether the contribution was unrestricted 
or restricted; if it was restricted, please explain all restrictions. 
Finally, if your company maintains a foundation or other separate 
charitable arm, please provide the name of all such entities, and list 
all donations made from that entity or entities.

    Answer. In the attached documents, we have provided information for 
the period January 1, 2015 through December 31, 2018 regarding payments 
made by Sanofi US to tax-exempt organizations.\5\ The information is 
provided in a number of documents consistent with how Sanofi maintains 
this information. In some cases, this information may be over-inclusive 
and include non-tax exempt organizations (e.g., contributions for 
independent medical education into both non-profit and other entities). 
The information includes contributions and sponsorships to various tax-
exempt health-care-oriented organizations, including patient groups. 
The information also includes contributions made for independent 
medical education grants, and to teaching hospitals for investigator-
sponsored trials and for physician fellowship payments. On March 8, 
2018, Sanofi acquired Bioverativ, Inc., a biopharmaceutical company 
focused on therapies for hemophilia and other rare blood disorders. The 
attached documents also describe the monetary contributions to tax 
exempt organizations made by Bioverativ since March 8, 2018.
---------------------------------------------------------------------------
    \5\ These contributions may not relate to particular drug products. 
Sanofi US supports programs and initiatives of external, independent, 
not-for-profit organizations that align with Sanofi US's corporate 
vision and values. These organizations are generally healthcare-
oriented and focus on one or more therapeutic areas in which Sanofi US 
is actively involved. The attached information focuses on Sanofi US 
entities that manufacture and sell drug products and does not include 
entities that manufacturer and sell consumer health products or 
vaccines. Contribution information prior to 2015 is archived in 
databases and systems that Sanofi does not currently maintain and which 
are not easily accessible. The information available does not 
distinguish between restricted and unrestricted grants.

    With respect to any foundations or charitable arms of Sanofi, from 
January 1, 2014 through the end of 2017, Sanofi maintained an entity 
called Sanofi Foundation of North America, a 501(c)(3) nonprofit 
operating foundation that was closed at the end of 2017. Donations made 
from that entity are included in the attachments described above. 
Currently, Sanofi maintains an entity called Sanofi Cares North 
America, which is a 501(c)(3) nonprofit operating foundation that makes 
donations of Sanofi products free of charge to eligible financially-
needy uninsured and underinsured patients through a program known as 
the Sanofi Patient Connection. Sanofi Cares North America also donates 
product to five non-governmental organization partners for the purpose 
of emergency disaster relief--Americares, DirectRelief, Heart to Heart 
International, MAP International, and Project Hope, and to 
approximately one hundred summer camps with 501(c)(3) status for 
---------------------------------------------------------------------------
children with diabetes.

    Question. Pay for delay agreements cost consumers and taxpayers 
billions in higher drug costs every year. The FTC has gone after drug 
companies that enter into these settlements where the brand pays the 
generic company to keep its lower cost alternative off the market. I'm 
the lead Republican sponsor of S. 64, the ``Preserve Access to 
Affordable Generics and Biosimilars Act,'' which would help put an end 
to these deals.

    Do you agree that these pay-off agreements keep drug costs high for 
patients because they delay competition?

    Answer. With respect to patent litigation, Sanofi believes it is 
inappropriate to presume that any settlement of patent litigations 
related to pharmaceutical products is anticompetitive. Patent 
settlements are often the most efficient and effective way to resolve 
disputes regarding patented drugs, and they often lead to the earliest 
appropriate entry of generic products into the market, which benefits 
patients. In fact, settlements permit entry of a generic alternative 
into the market earlier than expiration of the relevant branded 
product's patent. Each patent litigation and potential settlement 
presents unique factors and must be considered individually and in 
light of the relevant circumstances.

    Question. Has your company ever entered into these kinds of 
settlements with a generic company?

    Answer. No, Sanofi does not enter into ``pay for delay'' or 
``reverse payment'' agreements that prohibit generic drug or biosimilar 
development after the expiration of a patent. Sanofi has reached 
settlements in patent infringement cases, and these agreements have 
allowed the generic company to commercialize its product before the 
expiration of the branded product's patent(s).

    Question. Do you support the pay for delay bill?

    Answer. We support the intent behind this legislation to promote 
competition, including prohibitions on ``reverse payment'' agreements. 
However, we have significant concerns with the way that this bill is 
drafted, and therefore we do not support this particular legislation.

    We believe that it is inappropriate to make settlements of patent 
litigations presumptively illegal or to classify such settlements as 
anticompetitive. Such settlements can be the most efficient and 
effective way to resolve legitimate disputes regarding patented drugs, 
and they often lead to the earliest appropriate entry of generic 
products into the market, which in turn benefits patients. As stated 
above, each patent litigation and potential settlement presents unique 
factors and must be considered individually and in light of the 
relevant circumstances.

    Additionally, we have concerns that this bill could apply 
retroactively to agreements entered into after June 17, 2013. For 
clarity and certainty in the marketplace, any new legislation governing 
the settlement of patent litigation should apply prospectively only.
                           rebate traps/walls
    Question. I'm increasingly concerned about the effect of so-called 
``rebate traps'' or ``rebate walls'' on patients' access to quality, 
lower cost medicine. I understand there is ongoing litigation 
challenging these practices as anti-competitive.

    Does your company engage in the bundling of rebates over multiple 
products? If so, why? And what benefit does the consumer gain from 
that?

    Answer. Sanofi offers discounts in bundled sales arrangements only 
in limited circumstances. For example, Sanofi may offer bundled 
discounts on its products Toujeo' and Lantus' to 
ensure that both products attain a formulary position that benefits 
patients. This is especially important because the products may serve 
patients with different medical needs.

    Question. Does your company view these practices as anticompetitive 
or harmful to patients' access to quality, lower cost medicine?

    Answer. Sanofi prioritizes patient access to medications at a 
reasonable cost. Sanofi's arrangements with individual PBMs or insurers 
promote this goal by maintaining stability of supply at affordable 
prices. In competitive drug markets, Sanofi may enter into arrangements 
with particular PBMs or insurers that permit Sanofi to further reduce 
its prices on one or more medications in exchange for greater certainty 
regarding the amount of those medications it will sell over a specified 
term. These arrangements promote patient access to quality, affordable 
medications, are procompetitive, and comply with the antitrust laws.

    Moreover, in competitive drug markets Sanofi's ability to ensure 
patient access to affordable medications is affected both by PBMs and 
insurers (who may have considerable negotiating leverage over 
manufacturers) and by other manufacturers (who may respond to 
competition from Sanofi in a variety of ways). While some manufacturers 
may respond by building ``rebate walls'' or ``rebate traps'' around 
their products, Sanofi shares the Committee's concern about practices 
that are harmful to patients' access to quality, affordable medication.

    Question. If a policy were adopted to eliminate rebates, or to 
require that rebate savings be passed on to the consumer, would that in 
and of itself solve the issue of rebate ``traps'' and ``walls''? And 
would consumers benefit from such a policy?

    Answer. The elimination of safe harbor protection for rebates would 
remove incentives for manufacturers to attempt to influence formulary 
placement through such discounts. It is also possible that competitive 
products would be launched at lower list prices and more readily 
incorporated into formularies on the basis of their clinical benefits 
in a world without rebates. This would benefit the system overall, 
including consumers.
                              drug pricing
    Question. When setting the list price of a drug, does your company 
consider regulatory costs or compliance? If so, how specifically do 
those factors affect the list price of a drug? Please provide at least 
one specific example, if applicable, from your current product 
portfolio.

    Answer. The primary factors that Sanofi considers in setting list 
price include the value of the product, the competitive environment, 
patient affordability and access, investment in further product 
development or needs to reinvest in R&D more generally. In certain 
limited cases, Sanofi also will consider regulatory costs when setting 
the list price of a product. These factors may be considered, for 
example, where ongoing clinical trials are needed for a particular 
therapy or when the FDA mandates a Risk Evaluation and Mitigation 
Strategy (``REMS'') for a product--such as with Sanofi's drug 
Lemtrada. Sanofi does not, however, consider our routine and ongoing 
regulatory compliance efforts within the cost of our products. Rather, 
those efforts are considered part of Sanofi's operating costs.

    Question. When setting the list price of a drug, does your company 
consider the risk of liability or litigation? If so, how specifically 
do those factors affect the list price of a drug? Please provide at 
least one specific example, if applicable, from your current product 
portfolio.

    Answer. When conducting its pricing analysis for a new drug, Sanofi 
does not specifically consider the risk of liability or litigation 
associated with such product.

                                 ______
                                 
                Questions Submitted by Hon. Pat Roberts
    Question. What role do you see Value Based Arrangements (VBAs) 
playing in the effort to reduce prescription drug costs? What potential 
do these arrangements have to find the ``sweet spot'' between 
controlling costs to patients and encouraging innovation of new drugs?

    How can VBAs help lower what patients pay out-of-pocket?

    Can Congress do more to allow for and encourage the use of VBAs?

    Answer. Sanofi believes that encouraging an environment that is 
supportive of value-based arrangements would help promote drug 
affordability, increase patient access to medicines, and improve 
patient adherence and outcomes. Although there are different types of 
these agreements, value-based contracts generally tie prices and 
payments to the value of a particular prescription drug product--while 
potentially reducing patient out-of-pocket costs and providing patients 
with better access to the most innovative drug products. A manufacturer 
could, for example, condition payment for a product on its success in 
meeting a predefined clinical outcome, and this type of arrangement 
could make drugs more affordable and lower healthcare costs throughout 
the system.

    Facilitating value-based arrangements also could encourage new drug 
innovation, control costs for such new products, and recognize the full 
value of complex and personalized treatments. Nevertheless, despite the 
promise of these arrangements, industry stakeholders--including 
manufacturers and payers--need better legal and regulatory clarity. For 
example, we support the creation of a safe harbor from Anti-Kickback 
Statute liability to protect value-based agreements. We also are 
supportive of any legislation that would facilitate value-based 
arrangements and protect them from legal enforcement, such as the 
Patient Affordability, Value, and Efficiency Act (PAVE Act).

                                 ______
                                 
                Questions Submitted by Hon. John Cornyn
    Question. We continue to hear that rebates negotiated off of the 
list price of a drug are both good and bad.

    Pharmacy benefit managers and plans have argued that rebates are 
used to lower premiums across the board and that it is the best way to 
seek a price concession on otherwise expensive drugs.

    Your industry argues that these payers are insisting on higher 
rebates that can only be achieved by raising list prices.

    But patients often lose under this system, with out of pocket costs 
being tied to list price. Insulin patients appear to be routinely 
impacted by this perversity in the system.

    Please explain to the committee how your company would reduce list 
prices if rebates were no longer a part of the equation?

    What assurance can you provide that you would in fact lower your 
prices?

    What actions should be taken to ensure that patients are actually 
seeing the benefits of lower out of pocket costs?

    Answer. If (1) the proposed changes to the anti-kickback statute 
safe harbors were codified, and (2) Congress implemented similar 
changes to the commercial insurance market, Sanofi would lower the list 
prices of its prescription medications for products in competitive 
categories for which there is currently a material difference between 
list price and net price on the assumption that patient access and 
affordability would be improved. Sanofi also supports policy changes 
that would de-link other payments in the pharmaceutical supply chain 
from list price.

    We support extending the intent behind the anti-kickback statute 
safe harbor proposed rule to the commercial market so that incentives 
are aligned across the marketplace. Together, we believe these changes 
would facilitate Sanofi's ability to lower its list prices. However, we 
recommend a step-wise approach, implementing changes to the commercial 
market after the safe harbor rule is implemented on January 1, 2020. 
Such an approach would provide an opportunity for stakeholders and the 
government to identify unintended consequences, and address them, prior 
to extending these policies to the commercial market.

    We want to ensure that the new system achieves its goal of 
improving affordability for patients. For instance, CMS should monitor 
and evaluate how the new system affects formulary access, utilization 
management, and patient cost-sharing, particularly with respect to 
medicines with a lower list price. We also have concerns that changes 
to the rebate system may lead to new fees, which simply require 
manufacturers to pay previous rebate values in new ways, rather than 
creating savings for patients.

    Without a better understanding of how these policy changes 
ultimately would affect the competitive marketplace, patient access, 
and affordability, we are unable to quantify the amount of any 
potential list price reduction.

    With respect to actions that should be taken to ensure patients are 
seeing the benefit of lower out-of-costs, we support legislation that 
would incentivize manufacturers to lower list prices by connecting 
better patient access and affordability to such pricing actions.

    Question. If rebates are driving high list prices for drugs as drug 
manufacturers' claim, why do you think that Part B drugs, which have no 
PBM rebates, are also seeing significant price increases? Whose fault 
is that?

    Answer. Sanofi considers a variety of factors when setting or 
raising its list prices. These factors include the value of the 
product, the competitive environment, patient affordability and access, 
investment in further product development or needs to reinvest in R&D 
more generally. Within this framework, any list price increase is made 
consistent with our pricing principles, including our commitment to 
limit the total annual increase to a level at or below the NHE 
projected growth rate, as estimated by CMS.

    Although we agree that one factor in price increases across the 
industry may be the increased demand for rebates at the PBM and health 
plan level, that is not the only factor. In fact, Sanofi believes that 
reducing incentives for high prices throughout the supply chain by 
delinking payments from list price would have a meaningful impact on 
price and patient costs. This is true, for example, with group 
purchasing organizations (GPOs) that negotiate pricing for Part B 
providers. As with PBMs, these GPOs negotiate rebates and 
administrative fees that are linked to the list price of the product. 
These structures thus create the same misalignment of interests as in 
the PBM setting. It is important to note, as well, that the current 
average sales price (ASP)-based system for Medicare Part B works to 
moderate price growth because reimbursement reflects the weighted 
average of discounts given to providers, payers, and other commercial 
purchasers. This means that the Medicare program and its beneficiaries 
benefit from the discounts health plans and providers negotiate on 
these drugs. Due to this market-based competition, ASP reimbursement 
rates often are substantially lower than list prices.
                     biosimilar competition/insulin
    Question. Biosimilars have been much anticipated as a solution to 
the drug pricing crisis. In particular, the FDA is moving to make 
insulin a biologic that would be subject to biosimilar competition in 
the future.

    But we are hearing from all of you that the biosimilar market 
doesn't work and the benefit of these cheaper but equally effective 
alternatives are really not available to U.S. patients.

    Can a biosimilar version of insulin be part of the solution for 
diabetes patients?

    If so, what changes need to be made to the system so that patients 
and the taxpayer can realize the benefit of biosimilars? (Merck gave up 
on pursuing a biosimilar to Sanofi's Lantus.) \6\
---------------------------------------------------------------------------
    \6\ https://www.fiercepharma.com/pharma/merck-ditches-biosimilar-
lantus-but-will-ease-path-for-mylan-s-rival-insulin-product.

    Answer. Sanofi believes that biosimilars currently--and will 
continue to--result in increased competition. In fact, this type of 
competition has grown among insulin manufacturers in recent years, and 
we expect that it will continue to lower prices for patients with 
diabetes. For example, in 2016, Eli Lilly introduced a follow-on 
biologic to Sanofi's drug Lantus. Additionally, in 2018, Sanofi 
introduced Admelog, a follow-on biologic of Humalog, at a list price 
that was 15% lower than the reference product. Mylan also is developing 
a second follow-on insulin glargine that references Lantus, and Sanofi 
is developing a biosimilar insulin aspart, a rapid-acting insulin, 
which we expect to introduce in 2021. Sanofi expects that the already 
highly competitive diabetes drug market will become increasingly robust 
over time--including with the anticipated introduction of 
---------------------------------------------------------------------------
interchangeable biosimilar basal and rapid acting insulins.

    There are changes already in place that will help patients and 
taxpayers realize the benefit of biosimilars. Specifically, in March 
2020, certain biologics that are currently regulated as drugs, 
including long acting insulins, will be regulated as biologics and 
therefore will be subject to the existing biosimilars pathway. We 
expect the change in insulin regulation to spur the continued 
development of substitutable or interchangeable insulin products, and 
to increase competition in this space generally.

                                 ______
                                 
                 Questions Submitted by Hon. Todd Young
         re-evaluating business strategies in foreign countries
    Question. Since taking office, President Trump has made reducing 
drug prices one of his highest priorities--and has repeatedly spoken 
about his frustration with the U.S. subsidizing the costs of 
pharmaceuticals for the rest of the world. He has gone so far as to 
issue proposals, like the International Pricing Index (IPI) Model, in 
an attempt to bring down prescription drug prices.

    With the increased scrutiny of the industry and of the drug supply 
chain as a whole in the United States, have any of your companies re-
evaluated your business strategy in foreign countries? If not, then 
why?

    Answer. No, Sanofi has not reevaluated its business strategy in 
foreign countries. Other countries have implemented systems, such as 
price controls or reference price regimes, to directly and artificially 
regulate the price of medicines. In our experience, there is not an 
opportunity for Sanofi to negotiate prices with these foreign 
government payers. Sanofi's only choice is to accept the government-
mandated price, or to not sell the pharmaceutical in that country, 
which not only hurts a company financially, but more importantly harms 
patients.

    We note that, although these systems may be effective at 
controlling budgets for central payers, they come at a steep cost for 
patients, including severe access restrictions and rationing. For 
instance, one analysis of the report released to justify the 
International Pricing Index found that 96 percent of new cancer 
medicines are available in the U.S. compared to 71 percent in the 
United Kingdom and 65 percent in France.\7\
---------------------------------------------------------------------------
    \7\ http://phrma-docs.phrma.org/download.cfm?objectid=0C19E240-
19C7-11E9-87D20050569A4
B6C.

    As a Sanofi specific example, Dupixent is the first drug to be 
approved for moderate to severe atopic dermatitis (eczema) in the US. 
FDA granted Breakthrough Therapy designation to Dupixent as preliminary 
clinical evidence indicated that ``the drug may demonstrate substantial 
improvement over available therapy on clinically significant 
endpoint(s).'' Dupixent was approved by FDA in March 2017 under 
Priority Review, which means that FDA's goal is to take action on this 
application within 6 months (compared to 10 months under standard 
review). Within 24 hours of FDA approval, Sanofi shipped orders for 
Dupixent to be made available to U.S. patients. In contrast, Health 
Canada approved Dupixent in November 2017. However, Dupixent is still 
---------------------------------------------------------------------------
not publicly reimbursed in Canada.

    Question. If a proposal, like IPI, were implemented, would it force 
your companies to potentially ``walk away from the negotiating table 
when other countries demand low prices subsidized by America's 
seniors,'' as HHS Senior Advisor for Drug Pricing Reform John O'Brien 
has said?

    Answer. In our experience, there is not an opportunity for 
manufacturers to negotiate with a government. Sanofi's only choice is 
to accept the government-mandated price, or to not sell the product in 
that country, which, as noted above, not only hurts Sanofi financially, 
but more importantly harms patients.

    Question. What are some of your ideas on how we can ensure 
Americans aren't shouldering the full cost of pharmaceuticals?

    Answer. While we understand the concern that Americans are 
shouldering more than their fair share of the cost of innovation in the 
pharmaceutical sector, the list price discrepancy between the U.S. and 
other countries is due, in primary part, to the different health care 
systems. Because Sanofi pays significant rebates to payers and PBMs, 
the difference between the price in other developed countries and the 
net price in the U.S. is not nearly as large.

    Sanofi's top priority is reducing out-of-pocket costs for patients. 
We believe that there need to be reforms to the current system to 
better align incentives, including market-based approaches to pricing 
that promote competition and ensure patients have affordable and 
sustainable access to innovative medicines. Currently, payers and PBMs 
inconsistently pass through the growing savings that they receive from 
increased negotiated rebates. Accordingly, despite increasing rebates 
and lower net prices, out-of-pocket costs for many patients have 
continued to grow. Sanofi supports policies that pass PBM and payer 
rebate savings to patients at the pharmacy counter through lower copays 
and coinsurance. Sanofi would also support policies that would 
incentivize responsible pricing by tying smaller list price increases, 
or even list price reductions, to both access and affordability for 
patients.
              foreign countries' pricing and reimbursement
    Question. President Trump and Secretary Azar have both repeatedly 
described their frustrations with ``foreign freeloading'' of U.S. drugs 
in the last year.

    ``When foreign governments extort unreasonably low prices from U.S. 
drug makers, Americans have to pay more to subsidize the enormous cost 
of research and development. . . . It's unfair and it's ridiculous, and 
it's not going to happen any longer.''

    Do you agree that because of foreign countries' pricing and 
reimbursement systems, U.S. patients and innovators are shouldering the 
burden for financing medical advances?

    Answer. It is true that the U.S. is the main engine in 
pharmaceutical and biotechnology innovation in the world. Although 
U.S.-based manufacturers manage clinical trials globally, there are 
substantially more research and development dollars invested in the 
U.S. than in any other country. To illustrate, in 2015, PhRMA member 
companies spent over $47 billion in domestic R&D and only $12 billion 
in R&D abroad. For Sanofi, in 2018, we spent nearly $7 billion on R&D 
globally--a substantial portion of which in the U.S.--and we expect 
that our annual R&D spend will be consistent through 2021. These 
investments in research, in turn, create significant and important job 
opportunities in the United States.

    However, it is important to note that while other countries' 
pricing and reimbursement systems may help to contain costs in those 
countries, they come at a steep cost for patients, including severe 
access restrictions and rationing. For instance, one analysis of the 
report released to justify the International Pricing Index found that 
96 percent of new cancer medicines are available in the U.S. compared 
to 71 percent in the United Kingdom and 65 percent in France.\8\ 
Moreover, the list price discrepancy between the U.S. and other 
countries is due, in part, to the different health-care systems. 
Because Sanofi pays significant rebates to payers and PBMs, the 
difference between the price in other developed countries and the net 
price in the U.S. is not nearly as large.
---------------------------------------------------------------------------
    \8\ http://phrma-docs.phrma.org/download.cfm?objectid=0C19E240-
19C7-11E9-87D20050569A4
B6C.

    Question. How do foreign countries' pricing and reimbursement 
---------------------------------------------------------------------------
systems affect our prescription drug costs?

    Answer. Pricing and reimbursement systems in other countries do not 
affect how Sanofi prices its medicines in the United States. Consistent 
with our pricing principles, when Sanofi sets the price of a new 
medicine in the U.S., we hold ourselves to a rigorous and structured 
process that includes consultation with external stakeholders. In our 
view, an objective measure of a new product's value considers the 
benefit to patients, compared to a standard of care; the reduced need--
and therefore costs--of other health-care interventions; and any 
increase in quality of life and productivity. We believe our pricing 
reflects these factors. We also consider factors such as the 
affordability for patients and any unique factors specific to the 
medicine, like the need to support ongoing clinical trials, implement 
important regulatory commitments, or develop sophisticated patient 
support tools that improve care management and help decrease the total 
cost of care. Additionally, under our pricing principles, we have 
pledged to limit price increases at or below the National Health 
Expenditure (NHE), which is the projected annual health-care spending 
growth rate as estimated by CMS.

    Question. Are foreign governments taking note of the concerns being 
raised by the Trump administration and have they responded in any way?

    Answer. Sanofi is not aware of any responses by foreign governments 
to U.S. drug pricing policy proposals advanced by the Trump 
administration.

    Question. Has there been any noticeable change in any of our trade 
agreements since these concerns have been raised by the Trump 
administration?

    Answer. Sanofi is not aware of any such changes.

                  medicaid closed formulary proposals
    Question. In an attempt to bring down drug costs, various States 
have been exploring whether to exclude certain drugs from their 
Medicaid program. For example, the State of Massachusetts recently 
asked CMS for permission to create a closed formulary where the State 
Medicaid program would pick at least one drug per therapeutic class. 
CMS denied their waiver request citing violation of Federal law, but 
this proposal does bring up important questions on how to contain drug 
prices in State Medicaid programs.

    If the principles of the Medicare Part D program--including the 
necessary patient protections--were applied to State Medicaid programs, 
do you think it would lower drugs costs while ensuring access to 
patients?

    Answer. The Part D program encourages strong competition in the 
marketplace, including by providing beneficiaries with choice of 
different plans and encouraging drug manufacturers to compete for 
formulary position to support broad access to their medicines (in part 
by securing lower cost-sharing obligations for patients in preferred 
formulary tiers). By contrast, State Medicaid programs are obligated, 
as a condition of a manufacturer's participation in the Medicaid Drug 
Rebate Program, to cover company's products (subject to certain narrow 
exceptions). Consequently, although we believe that increased 
competition in the Medicaid program could help to lower drug prices, 
including if Medicaid implemented certain of the Part D program's 
principles, it is not immediately clear how these changes would further 
enhance patient access.
                        medicaid ``best price''
    Question. In the Trump administration's Blueprint, they suggested 
that because drug manufactures have to give Medicaid the ``best price'' 
on drugs, there is no incentive to offer deeper discounts to other 
payers--both government and commercial--than what is already offered 
under the Medicaid Drug Rebate Program.

    Does the Medicaid ``best price'' requirement encourage 
manufacturers to increase initial prices?

    Answer. The Medicaid Rebate Act, and CMS's corresponding rules, 
require drug manufacturers to pay rebates to the State Medicaid 
Programs for units of drug dispensed to their beneficiaries. Medicaid 
``Best Price'' generally is defined as the lowest price offered to 
commercial purchasers in the United States, and it is one of two key 
metrics used for setting the level of rebates that manufacturers must 
pay to each state Medicaid program for Medicaid beneficiary 
utilization. Best Price does not, therefore, reflect a price point at 
which manufacturers sell products to Medicaid, and Sanofi does not view 
the Medicaid Best Price requirements as encouraging manufacturers to 
set higher initial prices. However, Medicaid Best Price considerations 
are a factor in assessing whether to offer higher rebate amounts to our 
commercial (Best Price-eligible) customers.

    Question. What, if any, changes would you suggest we make to the 
program?

    Answer. With regard to the Medicaid Drug Rebate Program and the 
determination of Best Price, the Trump administration's Pricing 
Blueprint highlights the impediments that exist under current rules 
with regard to value-based discounting arrangements. Sanofi would like 
to pursue more innovative product discounting strategies--including 
arrangements in which we would stand behind the value or outcomes that 
our products provide to patients and to the healthcare system 
generally. But, current Medicaid rebate calculation rules regarding 
bundled discount arrangements, and the manner in which manufacturers 
must account for discounts that are incurred over long periods of time, 
present significant obstacles to adopting these arrangements. If the 
rules for the Medicaid Drug Rebate Program were amended to permit 
manufacturers to exclude certain appropriately-structured value-based 
discounts from their Best Price calculation, it is likely that Sanofi 
could adopt more innovative value-based discount contracts, and that 
these arrangements in turn could result in significant savings for 
patients and the system.
                        outcomes-based contracts
    Question. In almost all of your testimonies, you highlight your 
support of outcomes-based contracts and how we need to be shifting our 
system toward that approach.

    How will these contracts lower drug costs for patients in both the 
near term and long-term?

    How will they lower overall health-care costs for our Federal 
programs?

    What have the preliminary results looked like so far?

    Answer. Sanofi believes that encouraging an environment that is 
supportive of value-based arrangements would help promote drug 
affordability, increase patient access to medicines, and improve 
patient adherence and outcomes. Specifically, value-based arrangements 
tie prices and payments to value while reducing patient out-of-pocket 
costs and providing patients with better access to the most innovative 
drug products. For example, value-based arrangements can be premised 
upon the effectiveness of a manufacturer's product, which may help to 
secure payer coverage for new and innovative therapies. Where payment 
to a manufacturer is conditioned on the value or clinical outcomes of a 
product, value-based arrangements also may help to improve patient 
cost-sharing challenges. Additionally, value-based arrangements could 
encourage new drug innovation while controlling costs for such new 
products by aligning the price of the drug to the value the drug brings 
to the patient.

    Recently, Sanofi has executed value-based contracts related to 
Soliqua 100/33, Praluent, and Kevzara. These arrangements are in their 
nascent stages, and we do not have sufficient information to assess the 
results.

    Despite the promise of these and similar arrangements, Sanofi 
strongly believes that better legal and regulatory clarity would 
facilitate greater proliferation of value-based contracts. For example, 
we support the creation of a safe harbor from Anti-Kickback Statute 
liability to expressly protect value-based agreements. We also are 
supportive of legislation that would remove Best Price-barriers to 
value-based contracts, such as the Patient Affordability, Value, and 
Efficiency Act (PAVE Act).
                       transparency/point of sale
    Question. In almost all of your testimonies, you express your 
support for the Trump Administration's proposal to allow manufacturers 
to provide PBMs up-front discounts that are passed onto patients at the 
point-of-sale.

    Do you feel like this proposal will make the transactions within 
the drug supply chain more transparent?

    If so, would this transparency bring down drug costs--overall and 
for specialty drugs?

    Answer. Because the proposed rule would require manufacturer 
discounts to be provided at the pharmacy counter, the proposal will 
facilitate increased transparency with respect to the arrangements 
between manufacturers and PBMs, and with respect to the discounts 
manufacturers offer on their medicines. We believe such increased 
transparency would result in lower patient costs.

    However, Sanofi believes that HHS's proposal does not go far enough 
in creating the kind of systemic change needed to create a more 
transparent drug supply chain throughout the entire U.S. health-care 
system. We believe that increased, system-wide transparency, that 
appropriately protects competitively sensitive information, would 
improve competition by making relevant information available to 
patients and policymakers. Providing more information about what is 
driving costs in the system, and taking steps to curtail misaligned 
incentives related to the flow of money through the system, for 
instance through legislation like the C-THRU Act, would allow for 
increased competition and better-informed decision making.
         the relationship between wholesalers and manufacturers
    Question. When talking about the pharmaceutical supply chain, a lot 
of focus has been placed on the Pharmacy Benefit Manager. But there's 
another side of the equation that I'd like to ask about.

    How do wholesalers negotiate pricing with manufacturers?

    What impact does this have on drug costs?

    What incentives or disincentives do they have to contain price 
increases?

    Answer. Wholesalers do not typically negotiate pricing with 
manufacturers. Wholesalers are merchant-middlemen in the supply chain, 
and they generally facilitate the efficient distribution of drugs and 
biologicals to end customers (such as pharmacies or clinics). While 
Sanofi may offer a prompt pay discount to wholesalers, wholesalers 
generally purchase product at Wholesale Acquisition Cost (i.e., list 
price) and they facilitate the acquisition of products by end 
purchases--frequently at prices that are negotiated between Sanofi and 
the end purchaser. If wholesalers sell to end purchasers at a loss 
based on the negotiated price, wholesalers will issue a ``chargeback'' 
to the manufacturer for the difference. In addition, Sanofi pays 
service fees to wholesalers to operationalize this distribution and 
chargeback process, and those fees typically are based on a percent of 
WAC. As with fees paid to PBMs, Sanofi's view is that flat pricing for 
wholesaler administrative services could exert downward pressure on 
drug prices by delinking list price from fee payments.

                                 ______
                                 
                 Questions Submitted by Hon. Ron Wyden
                          proposed rebate rule
    Question. As has been done in many other settings, drug 
manufacturers said during the hearing that one reason list prices for 
drugs are high is that pharmaceutical benefit managers (PBMs) demand 
larger and larger rebates in order for the drug to receive favorable 
placement on a formulary. You and your colleagues who testified during 
the hearing stated if the administration's proposal on changes to the 
anti-kickback safe harbor for pharmaceutical rebates took effect, your 
company would likely lower list price.

    Like many Oregonians, I am skeptical drug manufacturers would 
voluntarily lower their prices. Therefore, would you support 
legislation that would (1) make similar changes the administration has 
put forward related to Part D and Medicaid managed care, (2) change the 
rebate system in a similar way to the proposal for the commercial 
market, and (3) require drug makers to lower the list price of their 
drugs equal to the amount of rebates provided today?

    Answer. If (1) the proposed changes to the anti-kickback statute 
safe harbors were codified, and (2) Congress implemented similar 
changes to the commercial insurance market, Sanofi would lower the list 
prices of its prescription medications for products in competitive 
categories for which there is currently a material difference between 
list price and net price on the assumption that patient access and 
affordability would be improved. Sanofi also supports policy changes 
that would de-link other payments in the pharmaceutical supply chain 
from list price.

    We support extending the intent behind the anti-kickback statute 
safe harbor proposed rule to the commercial market so that incentives 
are aligned across the marketplace. Together, we believe these changes 
would facilitate Sanofi's ability to lower our list prices. However, we 
recommend a step-wise approach, implementing changes to the commercial 
market after the safe harbor rule is implemented on January 1, 2020. 
Such an approach would provide an opportunity for stakeholders and the 
government to identify unintended consequences, and address them, prior 
to extending these policies to the commercial market.

    We want to ensure that the new system achieves its goal of 
improving affordability for patients. For instance, CMS should monitor 
and evaluate how the new system affects formulary access, utilization 
management, and patient cost-sharing, particularly with respect to 
medicines with a lower list price. We also have concerns that changes 
to the rebate system may lead to new fees, which simply require 
manufacturers to pay previous rebate values in new ways, rather than 
creating savings for patients.

    Without a better understanding of how these policy changes 
ultimately would affect the competitive marketplace, patient access, 
and affordability, we are unable to quantify the amount of any 
potential list price reduction.

    We support legislation that would incentivize manufacturers to 
lower list prices by connecting better patient access and affordability 
to such pricing actions. The U.S. market-based approach to drug pricing 
has been successful in reducing net prices, but in the current system, 
that value is not being passed on to patients. We expect that the 
reforms we note above would address that issue while preserving a 
market-based approach that promotes competition and ensures patients 
have affordable and sustainable access to innovative medicines.
                      medicaid drug rebate program
    Question. The Medicaid Drug Rebate Program (MDRP) requires 
manufacturers to provide a basic rebate and an additional inflationary 
rebate for both brand and generic drugs. The inflationary rebate is an 
increasingly substantial part of total rebates due in large part to 
large increases in drug prices that exceed inflation. Under current 
law, this inflationary rebate is capped at 100 percent of Average 
Manufacturer Price (AMP). This is the case even when manufacturers 
continue to raise their prices well above inflation.

    Please provide a list of all of your pharmaceutical products that 
have reached the Medicaid AMP rebate cap in any of the 20 quarters from 
January 1, 2014 through December 31, 2018.

    For each drug listed in response to question 1, please also provide 
a list of which quarters and years each drug hit the cap.

    Answer. Sanofi takes steps to ensure that it complies with all 
applicable laws related to the Medicaid Drug Rebate Program, including 
that it is paying rebates to the state Medicaid programs in accordance 
with law. Sanofi sells NDCs in 29 product families for which it pays 
Medicaid rebates at 100 percent of AMP. Respectfully, Sanofi's view is 
that the detailed information requested by this question is 
confidential and proprietary. We would be happy to work with the 
Committee to provide this information in a way that mitigates against 
competitive harms that could arise from public disclosure of this 
information.
                medicaid drug rebate program compliance
    Question. I am concerned about recent reports and legal settlements 
surrounding drug manufacturers' failure to comply fully with the 
requirements of the MDRP. For example, an analysis by the U.S. 
Department of Health and Human Services Office of Inspector General 
found that between 2012 and 2016 taxpayers may have overpaid by as much 
as $1.3 billion for 10 potentially misclassified drugs. That is why I 
introduced the Right Rebate Act with Chairman Grassley to prevent drug 
manufacturers from manipulating Medicaid to increase their profits. 
However, I continued to be concerned about oversight and manufacturer 
compliance with the requirements of the Medicaid Drug Rebate Program. 
Accordingly, please describe the following:

    Your company's current compliance plan and procedures used to 
ensure compliance with the requirements of the Medicaid Drug Rebate 
Program including internal audits or other checks you use to identify 
compliance vulnerabilities.

    Answer. Sanofi takes steps to ensure that it complies with all 
applicable laws related to its participation in the Medicaid Drug 
Rebate Program (MDRP). These steps include, for example, documenting 
Medicaid rebate calculation methodologies, processes, and reasonable 
assumptions as appropriate. Sanofi's government price reporting 
personnel also hold weekly meetings with the Sanofi legal department, 
including with support from outside counsel as needed, to ensure that 
compliance questions are discussed and addressed in a timely manner. 
Sanofi's MDRP compliance is tested through several audits, including 
biannual Sarbanes-Oxley Act audits, biannual external audits, 
conversations with an external consultant government pricing advisory 
team, and annual calculation audits of Average Manufacturer Price and 
Best Price.

    Question. Any past or ongoing issues of non-compliance.

    Answer. Given the complexity of the MDRP and applicable law and 
guidance, Sanofi routinely reviews its calculation methodologies and 
reasonable assumptions. In the normal course of business, questions may 
arise as to specific Sanofi compliance processes for the MDRP. When 
such questions arise, Sanofi takes prompt steps to engage with CMS 
about appropriate next steps, including a restatement of any of the 
components of the Medicaid rebate calculation if needed. Such 
restatements are administrative in nature and expressly contemplated by 
the CMS regulations.

    Question. Any corrective actions taken to address identified 
problems or issues of noncompliance with the MDRP and how such steps 
were communicated to the Centers for Medicare & Medicaid Services.

    Answer. As noted above, in the event that Sanofi identifies any 
compliance questions that it believes warrant review by CMS, Sanofi 
promptly engages with CMS. This may occur, for example, in the event of 
statutory or regulatory changes, or if CMS releases new sub-regulatory 
guidance.

    Question. Any steps taken to improve compliance and ensure that all 
Medicaid drug rebates owed to the federal government and the states are 
paid in full.

    Answer. Sanofi's government price reporting team routinely works 
with in-house and outside counsel regarding compliance with the 
Medicaid Drug Rebate Act and CMS rules. As part of this continuing 
compliance, the company assesses its calculation processes and 
reasonable assumptions for purposes of calculating Average Manufacturer 
Price, Best Price, and Unit Rebate Amount. In certain cases, moreover, 
Sanofi engages directly with CMS to seek the agency's view of Sanofi's 
reasonable assumptions or compliance processes. In any instance in 
which Sanofi would determine that the State Medicaid Programs were 
underpaid rebates, Sanofi would engage with CMS to determine the 
appropriate way forward, including restating pricing metrics and paying 
additional rebates to the States.
                 bonus payments tied to specific drugs
    Question. I am concerned by the potential for employee financial 
incentives to encourage high launch prices and price increases for 
prescription drugs.

    Is your salary, bonus or other compensation tied to sales or 
revenue targets of a single product your company sells? Has it ever 
been? If yes, please state the product or products to which your 
salary, bonus or other compensation was tied.

    Is your salary, bonus or other compensation tied to either revenue 
or net income of the company as a whole? Has it ever been? If yes, 
please explain what assumptions about price increases are used when the 
compensation committee sets revenue or net income goals. Does the 
compensation committee provide any guidance to executives in regards to 
the amount of revenue that the company will generate from price 
increases versus volume growth?

    Answer. The Sanofi board of directors, acting on the recommendation 
of the Compensation Committee, sets the compensation for the chief 
executive officer (CEO). That compensation structure includes fixed 
compensation, variable compensation, options, performance shares, and 
benefits in kind.

    Sanofi's overall compensation policy is designed to motivate and 
reward performance by ensuring that a significant portion of 
compensation is contingent on the attainment of financial, operational, 
and extra-financial criteria aligned with the corporate interest and 
with the creation of shareholder value. Therefore, in 2017 (the most 
current year in which public information is available), as Sanofi's 
CEO, Dr. Brandicourt was eligible for up to 250 percent of his target 
fixed compensation in variable compensation. Several factors are 
considered in determining his variable compensation; 40 percent is 
based on financial indicators, and 60 percent is based on specific 
individual objectives, including external growth, product launches, 
operational transformation, organization and staff relations, and new 
product pipeline.

    Dr. Brandicourt's compensation package also includes equity-based 
compensation, which is medium-term and aims to align the interests of 
the CEO with those of the shareholders and other stakeholders. In 2017, 
he received a set number of options to subscribe for shares, based on 
performance conditions measured over a 3-year period, as well as 
performance shares based on business net income, return on assets, and 
total shareholder return.
                               net prices
    Question. In your testimony, you stated, ``we have increased 
transparency by providing, each year, information about our list and 
net prices across all of our medicines,'' and that ``in 2018, the 
average aggregate list price increase across all Sanofi medicines in 
the U.S. was 4.6 percent . . . the price actually paid to Sanofi, 
declined by 8 percent. So declining average aggregate net price in 
[2018] represents the third consecutive year in which the amount paid 
by payers across all of our medicines went down.'' Please describe how 
the company's year-over-year aggregate net price is calculated. Please 
also specifically address the following questions.

    Answer. Sanofi calculates the aggregate net price as follows: Brand 
net sales are divided by common units for the appropriate period. This 
amount--``net price per unit''--is then compared to the prior period. 
This amount establishes any increase or decrease for the brand for the 
period being calculated. Once this is done for all brands, the 
increase/decrease is weighted by gross sales (i.e., volume) to show the 
aggregate net price impacts for Sanofi's portfolio of medicines.

    Question. How many products are included in the calculation of the 
average net price change? What was the median net price change?

    Answer. This analysis is done on 79 separate products, covering 76 
brands. Some brands have multiple product forms with different prices; 
Sanofi separates these product forms when calculating average net 
price.

    The median net price change in 2018 was zero percent across all 
products. Removing products with no net price change, the median net 
price change in 2018 is -1.0%. This calculation is not weighted by 
gross sales.

    Question. Is net price weighted? If so, how? For example, in 
determining the aggregate net price does the company assign different 
weights to different products based on volume or other factors? Are 
``on patent'' and ``off patent'' drugs weighted identically? Are other 
statistical weights used or are all products treated equally?

    Answer. All products are weighted by gross sales (i.e., volume), 
irrespective of whether Sanofi has any current patents related to the 
product. No other statistical weights were used.

    Question. Does the figure that you provided during your testimony 
account for U.S. prices, international prices, or both? Generally 
speaking, when your company reports net price changes, does it 
differentiate between U.S. and international prices?

    Answer. The data Dr. Brandicourt provided regarding average 
aggregate list price and average aggregate net price accounted for U.S. 
prices. Sanofi's annual pricing report \9\ and related reporting on net 
price consider U.S. prices only.
---------------------------------------------------------------------------
    \9\ https://mediaroom.sanofi.com/-/media/Project/One-Sanofi-Web/
Websites/Global/Sanofi-COM/mediaroom/pdf/2019/
Prescription_Medicine_Pricing_2019.pdf.

    Question. Please list the five drugs your company sold in the U.S. 
that had the greatest year-over-year net price increase in 2018, noting 
the increase for each drug by dollar figure and percentage. Please list 
the five drugs your company sold in the U.S. that had the lowest year-
over-year net price increase (and/or the greatest decrease) in 2018, 
noting the increase (or decrease) for each drug by dollar figure and 
---------------------------------------------------------------------------
percentage.


     Products with Greatest Average Net Price Increases in 2018 \10\
------------------------------------------------------------------------
                                       YOY Percentage    YOY U.S. Dollar
               Product                     Change        Change by Unit
------------------------------------------------------------------------
Renvela \11\                                      40%             $1.00
------------------------------------------------------------------------
Imovax \12\                                       15%             30.10
------------------------------------------------------------------------
Caprelsa \13\                                     12%          1,536.60
------------------------------------------------------------------------
Hectorol \14\                                     11%              0.03
------------------------------------------------------------------------
Zaltrap \15\                                       9%              0.60
------------------------------------------------------------------------
\10\ We have excluded products that were discontinued/divested in 2018,
  have no sales in 2018, or if the reason for net price increase was due
  to changes in prior accounting estimates or assumptions (as opposed to
  changes in rebates and discounts).
\11\ Sanofi did not take any list price increases on Renvela in 2018.
  The net price increase is due to (1) changes in prior accounting
  estimates/assumptions, and (2) increasing use of generics in class,
  resulting in (i) change in the mix of business, and (ii) a reduction
  in rebate payments.
\12\ Sanofi took a 5-percent list price increase on Imovax in 2018.
\13\ Sanofi took a 5-percent list price increase on Caprelsa in 2018.
\14\ Sanofi reduced the list price of Hectorol by 47 percent in October
  2018. The net price increase was due to a reduction in rebate
  payments.
\15\ Sanofi did not take any list price increases on Zeltrap in 2018.


     Products with Greatest Average Net Price Decreases in 2018 \16\
------------------------------------------------------------------------
                                       YOY Percentage    YOY U.S. Dollar
               Product                     Change        Change by Unit
------------------------------------------------------------------------
Renvela AG                                       -74%             -1.57
------------------------------------------------------------------------
Zolpidem CR                                      -68%             -0.26
------------------------------------------------------------------------
Leflunomide                                      -63%             -0.59
------------------------------------------------------------------------
Clolar                                           -48%           -894.26
------------------------------------------------------------------------
Priftin                                          -26%             -0.54
------------------------------------------------------------------------
\16\ We have excluded products that were discontinued/divested, have no
  sales in 2018, or if the reason for net price decline was due to
  changes in prior accounting estimates or assumptions (as opposed to
  changes in rebates and discounts).


    Question. For 2018, what was the average net price change in the 
U.S. market for (1) drugs with no competition, (2) drugs with only 
branded competition, and (3) drugs with generic competition?

    Answer. (1) Drugs with no competition:\17\ 0.0%.
---------------------------------------------------------------------------
    \17\ We define a product as having no competition if there are no 
other products in the therapeutic class.

    (2) Drugs with only branded competition:\18\ -2.1%.
---------------------------------------------------------------------------
    \18\ We define a product as having only branded competition if 
there is no generic, follow-on biologic, or biosimilar product in the 
therapeutic class.

    (3) Drugs with AB-rated generic/follow-on biologic/biosimilar 
---------------------------------------------------------------------------
competition: -13.5%.

    Question. In its most recent pricing report, Sanofi states that it 
``increased the price of 35 of our 76 prescription medicines'' in the 
United States. This statement appears to be in regards to list price. 
How many of these medicines had their net price increase?

    Answer. Seventeen of the 35 prescription medicines with list price 
increases also had average net price increases.

    Question. In its most recent pricing report, Sanofi states that 
``in 2018, 55 percent of our gross sales were given back to payers as 
rebates, including $4.5 billion in mandatory rebates to government 
payers and $7.3 billion in discretionary rebates.'' For each product, 
please disclose the gross sales and the amount of rebates paid.

    Answer. Product-level rebate information is confidential and 
proprietary information for competitive reasons and falls within the 
definition of ``trade secret'' under the Trade Secrets Act, 18 U.S.C. 
Sec. 1905, Exemption 4 of the Freedom of Information Act, 5 U.S.C. 
Sec. 552(b)(4), and the Defend Trade Secrets Act of 2016, 18 U.S.C. 
Sec. 1836. Public disclosure of this information would cause 
significant harm to Sanofi and Sanofi's customers, and competitors 
would gain unfair competitive advantage if they were to obtain this 
information through public disclosure.

    We note that congressional and executive agencies have historically 
expressed concern that disclosure of such information could inhibit 
competition. For example, in 2007 when then-chairman Waxman asked 
several Medicare Part D prescription drug plans (``PDPs'') to submit to 
the House Oversight and Government Reform Committee information on the 
negotiated price discounts, rebates and other price concessions that 
they obtained from drug manufacturers, the CBO issued a report 
concluding that public disclosure of that information could reduce the 
rebates that PDPs received and thus raise Medicare costs.\19\ 
Specifically, the CBO found that the disclosure of rebate data could 
cause the variation in rebates among purchasers to decline. Because 
PDPs generally secure rebates that are somewhat larger than the average 
rebates observed in commercial health plans, the disclosure of Part D 
rebates to competitors could create pressure to reduce those rebate 
amounts, which in turn could increase costs for the Medicare program 
and, on average, the costs for Medicare beneficiaries.\20\ 
Specifically, the CBO found that the disclosure of rebate data could 
cause the variation in rebates among purchasers to decline. Second, CBO 
concluded that disclosure of rebates could facilitate tacit collusion 
among the manufacturers of competing brand-name drugs, reducing the 
rebates to PDPs and thus increasing net drug prices.\21\ Similarly, the 
Federal Trade Commission (``FTC'') has cited concerns regarding the 
anti-competitive effects of disclosing net pricing and other price-
sensitive information. In the context of the healthcare industry 
generally, the FTC noted:
---------------------------------------------------------------------------
    \19\  CBO, Letter to the Hon. Joe Barton and the Hon. Jim McCrery 
(March 12, 2007), available at https://www.cbo.gov/system/
files?file=2018-10/03-12-drug-rebates.pdf; see also CBO, ``Increasing 
Transparency in the Pricing of Health Care Services and 
Pharmaceuticals'' (June 5, 2008), available at https://www.cbo.gov/
sites/default/files/110th-congress-2007-2008/reports/06-05-
pricetransparency.pdf.
    \20\ Id., at 3.
    \21\ Id., at 4.

        [Price transparency] can actually harm competition and 
        consumers. Some types of information are not particularly 
        useful to consumers, but are of great interest to competitors. 
        We are especially concerned when information disclosures allow 
        competitors to figure out what their rivals are charging, which 
        dampens each competitor's incentive to offer a low price, or 
        increases the likelihood that they can coordinate on higher 
        prices.\22\
---------------------------------------------------------------------------
    \22\ FTC, Office of Policy Planning, ``Price Transparency or TMI?'' 
(July 2, 2015), available at https://www.ftc.gov/news-events/blogs/
competition-matters/2015/07/price-transparency-or-tmi.

    Moreover, in describing its concerns about a New York state bill 
that would have required pharmacy benefit managers (``PBMs'') to 
disclose their rebate arrangements with drug manufacturers, the FTC 
explained that disclosure of this information could ``facilitate 
collusion, raise prices, and harm the patients the Bill is supposed to 
protect.'' \23\ The FTC further explained that, without knowledge of 
such competitor rebate information:
---------------------------------------------------------------------------
    \23\ FTC, Office of Policy Planning, Bureau of Competition and 
Bureau of Economics, Letter to Hon. James L. Seward re: New York Senate 
Bill 58, at 5 (March 31, 2009), available at https://www.ftc.gov/sites/
default/files/documents/advocacy--documents/ftc-staff-comment-
honorable-james-l.seward-concerning-new-york-senate-bill-58-pharmacy-
benefit-managers-pbms/v090006newyorkpbm.pdf.

        [M]anufacturers have powerful incentives to bid aggressively 
        for formulary position, because preferential formulary 
        treatment may yield increased sales. Unprotected disclosures 
        thus may raise the price that New York consumers pay for 
        pharmaceutical coverage by undermining competition among 
        pharmaceutical companies for preferred formulary treatment.\24\
---------------------------------------------------------------------------
    \24\ Id. See, also, FTC, Office of Policy Planning, Bureau of 
Competition, and Bureau of Economics, to Assemblyman Greg Aghazarian 
re: California Assembly Bill No. 1960 (September 7, 2004) (concluding 
that, if manufacturers learn the exact amount of the rebates offered by 
their competitors through required PBM disclosures, then tacit 
collusion among manufacturers is more feasible, which may lead to 
higher prices for PBM services and drugs), available at https://
www.ftc.gov/sites/default/files/documents/advocacy_documents/ftc-
comment-hon.greg-aghazarian-concerning-ca.b.1960-requiring-pharmacy-
benefit-managers-make-disclosures-purchasers-and-prospective-
purchasers/v040027.pdf.

    For these reasons, in public settings, we have provided rebate 
information at an aggregate level only, to prevent reverse engineering 
by competitors to learn our net pricing information for specific 
products. We would be happy to work with the committee to provide this 
information in a way that mitigates against competitive harms that 
---------------------------------------------------------------------------
could arise from public disclosure of this information.

                                 ______
                                 
              Questions Submitted by Hon. Robert Menendez
    Question. When new products enter the market, do drug companies set 
high initial prices and then provide deep rebates in order to gain 
access to insurance plan's formularies?

    Answer. We can only speak for Sanofi. Consistent with our pricing 
principles, when Sanofi sets the price of a new medicine, we hold 
ourselves to a transparent, rigorous, and structured process that 
includes consultation with external stakeholders. In our view, an 
objective measure of a new product's value considers the benefit to 
patients, compared to a standard of care; the reduced need--and 
therefore costs--of other health care interventions; and any increase 
in quality of life and productivity. We believe our pricing reflects 
these factors. We also consider factors such as the affordability for 
patients and any unique factors specific to the medicine, like the need 
to support ongoing clinical trials, implement important regulatory 
commitments, or develop sophisticated patient support tools that 
improve care management and help decrease the total cost of care. 
Additionally, under our pricing principles, we limit annual list price 
increases to the National Health Expenditure, which is CMS's projected 
annual health-care spending growth rate. Since we established our 
pricing principles in 2017, all price increases for our insulin 
products have been at or below NHE.

    Sanofi offers rebates to health plans and PBMs in order to help 
secure and maintain favorable formulary positions. Our aim in these 
negotiations is to establish affordable access to patients. Currently, 
however, payers and PBMs inconsistently pass through to patients the 
growing savings they receive from increased negotiated rebates and 
discounts. Accordingly, despite increasing rebates and lower net 
prices, out-of-pocket costs for many patients have continued to grow. 
Sanofi supports policies that would pass through PBM rebate savings to 
patients at the pharmacy counter in the form of lower cost-sharing.

    Question. If CMS finalizes the rebate rule, do you anticipate 
future products entering the market with significantly lower initial 
list prices?

    Answer. We can only speak for Sanofi. If (1) the proposed changes 
to the anti-kickback statute safe harbors were codified, and (2) 
Congress implemented similar changes to the commercial insurance 
market, Sanofi would lower the list prices of its prescription 
medications for products in competitive categories for which there is 
currently a material difference between list price and net price on the 
assumption that patient access and affordability would be improved. 
Sanofi also supports policy changes that would de-link other payments 
in the pharmaceutical supply chain from list price.

    We support extending the intent behind the anti-kickback statute 
safe harbor proposed rule to the commercial market so that incentives 
are aligned across the marketplace. Together, we believe these changes 
would facilitate Sanofi's ability to lower our list prices. However, we 
recommend a step-wise approach, implementing changes to the commercial 
market after the safe harbor rule is implemented on January 1, 2020. 
Such an approach would provide an opportunity for stakeholders and the 
government to identify unintended consequences, and address them, prior 
to extending these policies to the commercial market.

    We want to ensure that the new system achieves its goal of 
improving affordability for patients. For instance, CMS should monitor 
and evaluate how the new system affects formulary access, utilization 
management, and patient cost-sharing, particularly with respect to 
medicines with a lower list price. We also have concerns that changes 
to the rebate system may lead to new fees, which would simply require 
manufacturers to pay previous rebate values in new ways, rather than 
creating savings for patients.

    Without a better understanding of how these policy changes 
ultimately would affect the competitive marketplace, patient access, 
and affordability, we are unable to quantify the amount of any 
potential list price reduction. When setting the price of a new 
medicine, Sanofi's decision making will continue to be guided by our 
pricing principles framework, which are discussed in Part 1 of this 
response.

                                 ______
                                 
              Questions Submitted by Hon. Thomas R. Carper
    Question. What are your recommendations for lowering prices for the 
40 percent of drugs that do not offer rebates in Medicare Part D? In 
the health insurance plans that you offer your employees, do you ask 
your insurers to pass through the full manufacturer rebates to the 
beneficiaries?

    Answer. To address prices of drugs that are not subject to rebates 
in Medicare Part D, Sanofi supports policies that would incentivize 
responsible pricing by tying smaller list price increases, or even list 
price reductions, to both access and affordability for patients. Sanofi 
also believes that value-based discounting arrangements could drive 
down the price of prescription drugs in all contexts, regardless of the 
existence of rebates, including for Medicare Part D. Sanofi favors 
reforms in applicable statutes and regulations to permit manufacturers 
and payers to adopt these arrangements more broadly than is the case 
today.

    The Sanofi medical plan is self-insured; as such, the company pays 
the majority (approximately 80 percent) of the health-care claims that 
are incurred by our employees and their dependents. Sanofi does not, 
therefore, pass rebates through to members. Importantly, the Sanofi PPO 
medical/Rx plan, which covers 90 percent of our employees who elect 
medical coverage, maintains very low member cost-sharing for 
prescriptions. For example, members incur no cost ($0 co-pays) for 
Sanofi and partner prescription drugs. For non-Sanofi prescriptions, 
the out-ofpocket expense varies for generic ($15/prescription), 
preferred brand ($25/prescription) and non-
preferred brand ($40/prescription).

    Question. The systems for pricing and distributing drugs are opaque 
and difficult to understand. What are your recommendations for 
increasing transparency in how your companies set the list prices for 
drugs, and for improving transparency in the supply chain for 
prescription drugs? Would you support federal standards for 
transparency in setting the list prices for drugs?

    Answer. Sanofi supports increased system-wide transparency, which 
would improve competition by making relevant information available to 
patients and policymakers. Two years ago, Sanofi announced our 
progressive and industry-leading pricing principles to help 
stakeholders understand our pricing decisions and to advance a more 
informed discussion of issues related to the pricing of medicines.\25\
---------------------------------------------------------------------------
    \25\ https://mediaroom.sanofi.com/en/articles/2017/sanofi-pricing-
principles-for-the-u-s/.

    Sanofi's pricing policy includes a commitment to transparency in 
how we price new medicines coming to the market for the first time. 
When Sanofi sets the price of a new medicine, we hold ourselves to a 
transparent, rigorous, and structured process that includes 
consultation with external stakeholders. In our view, an objective 
measure of a new product's value considers the benefit to patients, 
compared to a standard of care; the reduced need--and therefore costs--
of other health care interventions; and any increase in quality of life 
and productivity. We believe our pricing reflects these factors. We 
also consider factors such as the affordability for patients and any 
unique factors specific to the medicine, like the need to support 
ongoing clinical trials, implement important regulatory commitments, or 
develop sophisticated patient support tools that improve care 
---------------------------------------------------------------------------
management and help decrease the total cost of care.

    Tied to our pledge to keep annual list price increases at or below 
the projected U.S. National Health Expenditure growth rate, Sanofi has 
committed to providing its rationale should Sanofi increase any list 
price above the NHE growth rate, highlighting clinical value, real 
world evidence, regulatory change, new data, or other circumstances 
that support our decision. Sanofi also has committed to disclose 
annually our aggregate U.S. gross and net price changes from the prior 
calendar year. These data may help illustrate how pricing changes 
accrue to manufacturers versus others in the value chain, highlighting 
our discrete role in the broader U.S. health care system.

    We support Federal standards for transparency in the rationale for 
price increases above a certain threshold, provided that there are 
appropriate guardrails. Sanofi believes that increased transparency 
should accomplish three goals:

        (1)  Preempt similar state laws, as was done with the Sunshine 
        Act, to create a consistent reporting process.

        (2)  Ensure information that if released publically could be 
        anti-competitive is kept confidential.

        (3)  Take a holistic approach to transparency, such as 
        requiring PBMs to disclose when the net price of a medicine has 
        declined and whether the increased rebates are used to lower 
        costs for patients or for other reasons.

    We would be willing to work with this Committee on appropriate 
policy solutions.

    Question. In nearly every sector of the health-care industry, 
Medicare, Medicaid, employers, and insurers are moving away from fee-
for-service payments to reimbursements based on value and performance. 
Prescription drugs and medical devices were the glaring exceptions to 
this trend until recently. How many of your drugs are included in 
value-based contracts and how many patients are benefiting from them? 
How do these value-based contracts work to lower drug prices for both 
patients and taxpayers?

    Answer. At this time, Sanofi has entered into value-based 
arrangements involving three Sanofi products: Soliqua 100/33, Praluent, 
and Kevzara. At present, we are not able to identify the specific 
number of patients who benefit from these arrangements.

    Sanofi believes that encouraging an environment that is supportive 
of value-based arrangements would help promote drug affordability, 
increase patient access to medicines, and improve patient adherence and 
outcomes. Specifically, although there are different types of these 
agreements, value-based contracts generally tie prices and payments to 
the value of a particular prescription drug product--while potentially 
reducing patient out-of-pocket costs and providing patients with better 
access to the most innovative drug products. A manufacturer could, for 
example, condition payment for a product on its success in meeting a 
predefined clinical outcome, and this type of arrangement could make 
drugs more affordable and lower costs throughout the system.

    Question. Last year, Senator Portman and I did an investigation on 
the pricing of an opioid overdose reversal drug called EVZIO, 
manufactured by Kaleo. Kaleo increased the price of EVZIO from $575 in 
2014 to $4,100 in 2017. We found that the best price Medicare was able 
to get for EVZIO, about $4,000, was much higher than the price other 
Federal programs and private insurers were able to get. It seemed that 
Kaleo was able to get this higher price of $4,000 from Medicare by 
helping doctors fill out paperwork showing that the drug was medically 
necessary, even though there are cheaper alternatives on the market. As 
a result of the investigation, Kaleo announced it will bring a generic 
version of the drug to market at only $168 per pack. Are any of your 
companies providing medical necessity paperwork to doctors in order to 
get your drugs covered by Medicare?

    Answer. No. Sanofi does not provide patient-specific clinical or 
medical necessity information to physicians in furtherance of the 
Medicare coverage of any of Sanofi's products for particular patients. 
Consistent with guidance from the Department of Health and Human 
Services Office of Inspector General (OIG), Sanofi typically provides 
physicians with a copy of an applicable blank prior authorization form, 
or in some cases, the form with only the physician's demographic 
information filled out, along with separate instructions for filling 
out the form. Also, in keeping with OIG guidance, Sanofi provides 
physicians with template appeals letter for instances in which a 
physician needs to appeal non-coverage for a Sanofi product. These 
template letters do not include any patient medical information, and 
instead are provided only as a guide for physicians to describe the 
reasons that the patient requires his or her prescribed Sanofi 
product.\26\ Similarly, Sanofi provides physicians with template 
letters of medical necessity, which do not offer medical information on 
specific patients. Instead, these documents provide a general framework 
pursuant to which physicians may prepare their own, patient-specific 
letters of medical necessity.\27\ These measures comply with the OIG 
guidance in that they provide ``limited support'' in connection with a 
purchase or prescribing decision for a Sanofi product.
---------------------------------------------------------------------------
    \26\ See, e.g., https://www.visitspconline.com/servlet/
servlet.FileDownload?file=00P3600000Q1T
boEAF. 
    \27\ See, e.g., https://www.visitspconline.com/servlet/
servlet.FileDownload?file=00P3600000Q1T
byEAF.

    Question. In 2017, the Rand Corporation estimated that biosimilar 
drugs, which are competitors to complex, biologic drugs, could save the 
United States more than $50 billion over the next decade. Some of you 
have also argued that increasing the use of biosimilar drugs would help 
lower drugs costs for consumers and taxpayers. What is delaying the 
uptake of biosimilar drugs in the United States? What policies do you 
---------------------------------------------------------------------------
recommend to increase the development of biosimilar drugs?

    Answer. Sanofi supports the entry of biosimilar medicines in the 
market after a reasonable period of time after the innovator biologic 
is developed, which we believe is already reflected in U.S. law. There 
are changes already in place that will help patients and taxpayers 
realize the benefit of biosimilars. Specifically, in March 2020, 
certain biologics that are currently regulated as drugs, including long 
acting insulins, will be regulated as biologics and therefore will be 
subject to the existing biosimilars pathway. We expect the change in 
regulation to spur the continued development of substitutable or 
interchangeable products, and to increase competition in this space 
generally. Further, we believe that as health-care providers become 
more familiar with biosimilars, the uptake of biosimilar drugs will 
increase. Findings from a recent review show that there is an overall 
lack of biosimilar familiarity among U.S. and European health-care 
providers, leading to low prescribing comfort as well as safety and 
efficacy concerns.\28\ The study concludes that, to realize the full 
cost-saving potential of biosimilar medicines, clinician-directed 
biosimilar education is necessary to address the gaps in biosimilar 
knowledge, facilitate prescribing changes, and ultimately increase 
biosimilar use.
---------------------------------------------------------------------------
    \28\ See ``Factors Affecting Health Care Provider Knowledge and 
Acceptance of Biosimilar Medicines: A Systematic Review,'' 25 J. 
Managed Care & Specialty Pharm. 102-112 (Jan. 2019), available at 
https://www.jmcp.org/doi/10.18553/jmcp.2019.25.1.102.

                                 ______
                                 
             Questions Submitted by Hon. Benjamin L. Cardin
    Question. The United States is one of the only countries in the 
world to allow prescription drug manufacturers to advertise directly to 
consumers through magazines, billboards, radio, and television 
commercials. While I will not argue that it is beneficial to educate 
consumers about an unfamiliar disease and encourage them to seek 
medical help, most commercials from all of your companies recommend 
asking about a specific brand name drug, not a medical condition. 
Furthermore, even if your advertisements follow all FDA rules and list 
medication side effects, they also almost always list these while a 
smiling, apparently healthy person is walking on a beach.

    Researchers say that this type of imagery, combined with viewing 
hours of drug commercials each month, leads consumers to underestimate 
the risks associated with medications. For the past decade, studies 
have shown that aggressive direct-toconsumer advertising is associated 
with rising drug prices and an increase in inappropriate drug 
prescriptions.

    Since researchers have concluded that consumers are 
misunderstanding the benefits and risks described in your ads, what 
further policies could help you and your colleagues ensure that you are 
educating patients in a clear manner?

    Answer. Sanofi believes DTC advertisements can play an important 
role in both raising awareness about a disease and educating patients 
about their treatment options. The benefits of DTC advertisements are 
reflected in the results of a recent survey conducted by Princeton 
Survey Research Associates International, which found that DTC 
advertisements often prompt conversations about alternatives such as 
generics or lifestyle changes, and prompt positive behaviors, such as 
information-seeking and medicine adherence.\29\
---------------------------------------------------------------------------
    \29\ https://www.phrma.org/report/2017-direct-to-consumer-
advertising-survey-results.

    When DTC advertisements solely discuss a particular disease or 
condition without mentioning or alluding to a specific drug, FDA 
considers the advertisements disease awareness communications. Disease 
awareness communications are not considered promotional labeling or 
advertising, and thus such communications are not subject to the 
requirements of the Federal, Food, Drug and Cosmetic Act (FDCA) or FDA 
regulations. In contrast, DTC advertisements that make claims about a 
drug are subject to requirements governing disclosure of risk and other 
information, including a statutory requirement to include a brief 
summary relating to side effects, contraindications, and effectiveness. 
FDA's prescription drug advertising regulations distinguish between 
print and broadcast advertisements, which require a ``brief summary'' 
for print advertisements and what is referred to as a ``major 
statement'' of risks for broadcast advertisements. FDA regulations also 
set forth additional requirements for information to be included in 
both print and broadcast advertisements. Certain broadcast 
advertisements, including the initial television advertisement for a 
prescription drug and all television advertisements for prescription 
drugs subject to a Risk Evaluation Mitigation Strategy with elements to 
assure safe use, are subject to pre-dissemination review by FDA. Even 
where a television advertisement is not subject to mandatory review, 
sponsors may elect to voluntarily submit the advertisement to FDA for 
---------------------------------------------------------------------------
advisory review.

    While the time-limited nature of broadcast DTC advertisements can 
present challenges in ensuring a drug advertisement presents all 
information required by the FDCA and FDA regulations in a manner easily 
digestible to a consumer, or even HCP, audience, Sanofi strives to 
disseminate balanced DTC advertisements that clearly and effectively 
communicate a product's benefits and risks. To that end, prior to 
airing any DTC television advertisement, Sanofi submits each 
advertisement to FDA for pre-dissemination review and incorporates 
FDA's comments, even when such review is not required for the 
advertisement in question. To further the objective of ensuring that 
DTC advertisements educate consumers about potential treatment options 
in a non-misleading manner, we believe industry would benefit from a 
regulatory framework that allows for greater flexibility in the risk 
and other information required to be included in broadcast 
advertisements, including, for example, the flexibility to focus on 
select significant risks in the advertisement itself while directing 
consumers to a website for a more fulsome discussion of a product's 
risks. FDA has acknowledged that its regulations provide ``only limited 
flexibility'' for risk disclosure in broadcast advertisements. Thus, 
allowing for greater flexibility in content control in DTC 
advertisements would likely require amending existing FDA regulations, 
as well as potentially the underlying statutory provisions governing 
the information required to be disclosed in advertisements.
           pharmaceutical companies continue to raise prices
    Question. As you are well aware, high prescription drug prices are 
the number one concern for Americans and their families. According to 
the Organization for Economic Cooperation and Development, the average 
American spends around $1,208 annually on prescription drugs. There 
have been several instances where brand name or even generic drugs that 
have been on the market for years continue to increase in price.

    One of the most well-known examples is Mylan's increase of the 
price of EpiPen from less than $100 in 2007 to more than $600 in 2016. 
Another example, is the ever-increasing price of insulin. Sanofi 
increased the price of a vial of Lantus from $88.20 in 2007 to $307.20 
in 2017. And those are just a small sample of price increases.

    Why don't we see price decreases for drugs that have been on the 
market for years without new formulations or added benefit?

    Answer. Current regulations, including price reporting 
requirements, create uncertainty about the implications of lowering a 
list price. We are working with CMS on alternatives that could enable 
us to put lower list price versions of our products on the market. 
Until such system changes are implemented, we are working to improve 
the affordability of our products for those who are uninsured or 
underinsured through our many patient support programs.

    It is important to note, as well, that revenues from existing 
therapies are used to fund future R&D across therapeutic areas. 
Sanofi's R&D strategy is to allocate resources to priority therapeutic 
areas based both on scientific opportunity and unmet medical need, 
leveraging multiple therapeutic modalities and accelerating early 
development. Our R&D pipeline currently contains 81 projects, including 
33 new molecular entities in clinical development, and 35 projects are 
in Phase III or have been submitted to regulatory authorities. From 
2008 to 2017, Sanofi invested over $55 billion dollars globally in R&D. 
Last year we invested almost $7 billion globally, or approximately 24% 
of our gross profits, in our research and development activities. We 
expect to continue to spend around the same on R&D in the coming years.
                             pay for delay
    Question. Pay for delay is a tactic that more and more branded drug 
manufacturers have been using to stifle competition from lower-cost 
generic manufacturers. This allows you to sidestep competition by 
offering patent settlements that pay generic companies not to bring 
lower-cost alternatives to market.

    These ``pay-for-delay'' patent settlements benefit both brand-name 
pharmaceutical companies by helping them avoid costly patent litigation 
and general manufacturers by rewarding them a hefty sum to delay 
entering the market with a cheaper drug alternative. However, these 
deals do not benefit consumers. According to an FTC study, these 
anticompetitive deals cost consumers and taxpayers $3.5 billion in 
higher drug costs every year.

    Does your company partake in pay-for-delay settlements?

    Answer. No, Sanofi does not enter into ``pay for delay'' agreements 
that prohibit generic drug or biosimilar development after the 
expiration of a patent. Sanofi has reached settlements in patent 
infringement cases, and these agreements have allowed the generic 
company to commercialize its product before the expiration of the 
applicable patent covering Sanofi's innovator product.

    Question. Why would a pharmaceutical company enter into a pay-for 
delay agreement?

    Answer. We can only speak for Sanofi, and we do not enter into 
``pay-for-delay'' settlement agreements.

    Question. Do you think these agreements stifle competition and 
prevent generic alternatives to your branded medications?

    Answer. With respect to patent litigation, generally, Sanofi 
believes it is inappropriate to presume that any settlement of patent 
litigations related to pharmaceutical products is anticompetitive. Such 
settlements are often the most efficient and effective way to resolve 
disputes regarding patented drugs. Additionally, they often lead to the 
earliest appropriate entry of generic products into the market thereby 
benefiting patients--earlier than expiration of the relevant patents. 
Each patent litigation and potential settlement presents unique factors 
and must be considered individually and in light of the relevant 
circumstances.
                            drug rebate rule
    Question. In January, the Department of Health and Human Services' 
(HHS) Office of Inspector General (OIG) promulgated a new regulation to 
remove regulatory safe harbor protections under the Anti-Kickback 
Statute (AKS) for rebates on prescription drugs rebates paid by 
manufactures to PBMs under Medicare Part D and for Medicaid managed 
care organizations (MCOs). The OIG proposal attempts to ban most 
rebates by eliminating their regulatory protections.

    The rule is predicted to increase net drug costs in its early 
years. The CMS actuaries estimate it would cost $196 billion over 10 
years. Despite this high price tag, the beneficiary benefits are 
limited. The proposed rule notes that under the CMS Actuary's analysis, 
the majority of beneficiaries would see an increase in their total out-
of-pocket payments and premium costs; reductions in total cost sharing 
will exceed total premium increases.

    I wanted to ask a question about the administration's rebate rule, 
which I understand that many of the drug manufacturers, and your main 
trade association, strongly support. According to an analysis of the 
rule by the Office of Actuaries at CMS, drug manufacturers are likely 
to initially retain 15 percent of the current rebates as higher net 
drug prices.

    Given that estimate, can you provide the committee with any 
assurances that prices will not increase under this proposed rule?

    Answer. At this time, it is difficult to predict the effect of the 
administration's proposed rule. It is our expectation that it will 
result in lower out-of-pocket costs for patients by protecting only 
manufacturer rebates to Medicare Part D and Medicaid MCO plans and 
their PBMs that are reflected in the point-of-sale price. Without a 
better understanding of how these policy changes ultimately would 
affect the competitive marketplace, patient access, and affordability, 
however, we are unable to provide assurances regarding how prices might 
change.

    We want to ensure that the new system achieves its goal of 
improving affordability for patients. For instance, CMS should monitor 
and evaluate how the new system affects formulary access, utilization 
management, and patient cost-sharing, particularly with respect to 
medicines with a lower list price. We also have concerns that changes 
to the rebate system may lead to new fees, which simply require 
manufacturers to pay previous rebate values in new ways, rather than 
creating savings for patients.

                                 ______
                                 
               Questions Submitted by Hon. Sherrod Brown
    Question. According to an article recently published in the Journal 
of the American Medical Association, medical marketers spent nearly $30 
billion dollars in 2016, up from $17 billion in 1997. Direct-to-
Consumer (DTC) advertising had the biggest percentage increase: from 
$2.1 billion, or 11.9% of all medical marketing, in 1997 to $9.6 
billion, or 32% of total spending, in 2016.

    Can each of you please provide what your ratio of spending on sales 
and marketing to research and development is today?

    Answer. In 2018, Sanofi's global ratio of spending on sales and 
marketing \30\ to research and development was approximately 117 
percent.
---------------------------------------------------------------------------
    \30\ ``Sales and marketing'' includes, but is not limited to: sales 
force, promotion, and marketing management.
---------------------------------------------------------------------------
                             price-gouging
    Question. Sanofi, as I understand it, has made a pledge to the 
public to limit its price increases to the national health expenditures 
growth projection.

    As the chair of the board of directors at PhRMA would you support 
membership requirements that would cap annual price increases for drugs 
sold as part of Medicare, similar to what Sanofi has pledged?

    Given that PhRMA members are considering creating higher standards 
for themselves, would you support an industry-wide standard on annual 
price increases that applies to all pharmaceutical corporations, 
whether or not they are members of PhRMA?

    Answer. Dr. Brandicourt appeared before the committee on behalf of 
Sanofi; we cannot speak on behalf of PhRMA or any other company. We 
note that pricing discussions among PhRMA members, or pharmaceutical 
manufacturers more generally, could implicate federal antitrust laws 
and therefore would be inappropriate.

    Two years ago, Sanofi announced our progressive and industry-
leading pricing principles, which include a pledge to keep annual list 
price increases at or below the projected U.S. National Health 
Expenditure (NHE) growth rate, as calculated by CMS. In 2018, all of 
Sanofi's price increases across its medicines were consistent with 
those pricing principles, as are all pricing actions taken in 2019.

    Question. What policies would you propose to help ensure lower 
launch prices for new drugs?

    Answer. For Sanofi, the key requirement for any policy solution is 
that it should result in improved access and lower prescription out-of-
pocket drug costs for patients, while maintaining incentives for 
innovations. To reform the current misaligned incentives in the current 
system, Sanofi supports de-linking payments to PBMs, payers and others 
in the supply chain from the list price. Additionally, we support 
policies that would incentivize lower launch prices, smaller list price 
increases, or even list price reductions, by requiring health plans to 
cover those medicines at an affordable co-pay level and only allow 
access restrictions consistent with the label and accepted best 
clinical practice.
                              transparency
    Question. In many of your testimonies, you mentioned that the 
current system of pharmacy benefit manager (PBM) back-end rebates do 
not rarely results in a scenario where the PBM passes on savings to 
consumers at the point of sale (POS). The Administration recently 
proposed a rule to eliminate the anti-kickback statute safe harbor 
protections for these drug rebates.

    Do you agree that greater transparency should be required to 
understand how manufacturers and PBMs are negotiating prices and 
rebates to ensure that savings are passed down to beneficiaries?

    Answer. Yes. Sanofi supports policies, such as those proposed in 
the C-THRU Act, that would encourage or require PBMs and payers to be 
transparent regarding how they use manufacturer rebates and pass 
through manufacturer rebates to patient at point of sale in the form of 
lower out-of-pocket costs.

    As part of our pricing principles, Sanofi voluntarily discloses 
annually our aggregate U.S. gross and net price changes from the prior 
calendar year. These data help illustrate how pricing changes accrue to 
manufacturers versus others in the value chain, highlighting our 
discrete role in the broader U.S. health care system.
                                  pbms
    Question. An Axios article from March 7, 2019 highlights the fact 
that, while ``pharmaceutical companies put a lot of the blame for high 
drug prices on pharmacy benefit managers,'' many large pharmaceutical 
companies ``rely on PBMs to manage their own health-care benefits.''

    In your role as an employer, does your company contract with a 
pharmaceutical benefit manager (PBM) to administer the prescription 
drug benefits for your employees and negotiate lower drug costs on your 
behalf?

    Answer. Yes, we do.

    Question. For those of you who do use a PBM to help manage the 
prescription drug benefit for your employees, how do you utilize the 
rebates your PBM negotiates to lower health-care costs or drug costs 
for your employee plans and what does your company do with that 
savings? Specifically, do the savings go toward lowing premiums?

    Answer. The Sanofi medical plan is self-insured; as such, the 
company pays the majority (approximately 80 percent) of the health-care 
claims that are incurred by our employees and their dependents. 
Therefore, Sanofi uses rebates to defray the overall cost of its health 
plan, which allows us to keep plan costs stable for all participants.

    We offer our employees generous healthcare coverage and have been 
able to keep the deductibles of our PPO, which covers 90% of our 
employees who elect medical coverage, at $200 for single coverage and 
$400 for family coverage over the past few years. With respect to our 
PPO prescription drug benefit, members incur no cost ($0 co-pays) for 
Sanofi and partner prescription drugs. For non-Sanofi prescriptions, 
the out-of-pocket expense varies for generic ($15/prescription), 
preferred brand ($25/prescription) and non-preferred brand ($40/
prescription). The Sanofi plan's actuarial value is around 90%, which 
puts it at the ``platinum'' level.

    Question. For those of you who do use a PBM to help manage the 
prescription drug benefit for your employees, does your PBM offer 
point-of-sale rebates to your employees?

    Answer. Yes, our PBM does offer point-of-sale rebates, however only 
around 8 percent of its clients currently are enrolled in point-of-sale 
rebates.

                                 ______
                                 
             Questions Submitted by Hon. Sheldon Whitehouse
    Question. Please describe any policy changes you support that would 
result in your company lowering the list prices of its drugs.

    Answer. For Sanofi, the key requirement for any policy solution is 
that it should result in improved access and lower prescription out-of-
pocket drug costs for patients, while maintaining incentives for 
innovations. To reform the current misaligned incentives in the current 
system, Sanofi supports de-linking payments to PBMs, payers and others 
in the supply chain from the list price. Additionally, we support 
policies that would incentivize lower launch prices, smaller list price 
increases, or even list price reductions, by requiring health plans to 
cover those medicines at an affordable co-pay level and only allow 
access restrictions consistent with the label and accepted best 
clinical practice.

    Sanofi also supports the intent behind legislation like the SPIKE 
Act, which would impose price transparency requirements on companies 
that increase the list price of a particular drug over a certain 
threshold. We believe that increased transparency should accomplish 
three goals: (1) preempt similar state laws, as was done with the 
Sunshine Act, to create a consistent reporting process; (2) ensure 
information that if released publically could be anti-competitive is 
kept confidential; and (3) take a holistic approach to transparency, 
such as requiring PBMs to disclose when the net price of a medicine has 
declined and whether the increased rebates are used to lower costs for 
patients or for other reasons.

    Question. How much does your company's research and development 
portfolio rely on taxpayer-funded research conducted by the National 
Institutes of Health (NIH)? How many of your company's products are 
based, at least in part, on NIH research, and how many are the result 
of research funded solely by your company?

    Answer. In identifying targets for new drugs, Sanofi relies on 
global science, which often includes NIH-funded research. Sanofi has 
collaborated with NIH on various research and development (R&D) 
initiatives on projects related to HIV, 
Epstein-Barr virus, influenza, and respiratory syncytial virus.

    While there is no question that NIH plays a vital role in basic 
research and early discovery, the majority of Sanofi's current 
portfolio of products in the pre-development to development phases do 
not rely on NIH funding. Sanofi reinvests a significant portion of its 
revenue into the R&D of new or improved medicines and vaccines. Last 
year, Sanofi globally spent almost $7 billion on R&D globally, an 
increase of approximately 7 percent from 2017, which reflects our 
commitment to bringing better therapies to patients. Sanofi plans to 
maintain this level of R&D investment through 2021, and our R&D 
pipeline now contains 81 projects, including 33 new molecular entities 
in clinical development, and 35 projects that are in Phase III or have 
been submitted to regulatory authorities. This investment means that 
Sanofi potentially will seek approval for nine new medications in the 
next three years, primarily in therapeutic areas where Sanofi sees the 
greatest nexus between our expertise and patient need: diabetes, 
vaccines, oncology, immunology, rare diseases, and rare blood 
disorders.

    Question. In each of the last 5 years, how much has your company 
spent on research and development versus the advertising and marketing 
of your products?

    Answer.


------------------------------------------------------------------------
                                        Research and     Advertising and
              USD \31\                   Development     Marketing \32\
------------------------------------------------------------------------
2018                                    $6,954,920,000    $4,519,400,000
------------------------------------------------------------------------
2017                                    $6,238,080,000    $3,764,280,000
------------------------------------------------------------------------
2016                                    $5,689,200,000    $3,006,300,000
------------------------------------------------------------------------
2015                                    $5,590,200,000    $2,773,100,000
------------------------------------------------------------------------
2014                                    $6,160,440,000    $2,673,000,000
------------------------------------------------------------------------
\31\ Sanofi reports its financials in Euros. All financial figures
  reported in this document have been converted from Euros into U.S.
  dollars. These are Sanofi global financial figures.
\32\ Includes global spending on ``promotion'' and ``marketing
  management.''


    Question. During the hearing, you mentioned that your company would 
be likely to lower the list prices of its drugs if the recent proposal 
by the Trump administration to change the current system of rebates was 
extended to the private market.

    If the policy was extended to the private market, how large would 
the list price reductions be relative to the size of the rebates your 
company is currently providing?

    Answer. If (1) the proposed changes to the anti-kickback statute 
safe harbors were codified, and (2) Congress implemented similar 
changes to the commercial insurance market, Sanofi would lower the list 
prices of its prescription medications for products in competitive 
categories for which there is currently a material difference between 
list price and net price on the assumption that patient access and 
affordability would be improved. Sanofi also supports policy changes 
that would de-link other payments in the pharmaceutical supply chain 
from list price.

    We support extending the intent behind the anti-kickback statute 
safe harbor proposed rule to the commercial market so that incentives 
are aligned across the marketplace. Together, we believe these changes 
would facilitate Sanofi's ability to lower its list prices. However, we 
recommend a step-wise approach, implementing changes to the commercial 
market after the safe harbor rule is implemented on January 1, 2020. 
Such an approach would provide an opportunity for stakeholders and the 
government to identify unintended consequences, and address them, prior 
to extending these policies to the commercial market.

    We want to ensure that the new system achieves its goal of 
improving affordability for patients. For instance, CMS should monitor 
and evaluate how the new system affects formulary access, utilization 
management, and patient cost-sharing, particularly with respect to 
medicines with a lower list price. We also have concerns that changes 
to the rebate system may lead to new fees, which simply require 
manufacturers to pay previous rebate values in new ways, rather than 
creating savings for patients.

    Without a better understanding of how these policy changes 
ultimately would affect the competitive marketplace, patient access, 
and affordability, we are unable to quantify the amount of any 
potential list price reduction.

    Question. How will this proposal affect how your company sets the 
list prices for new drug products?

    Answer. When setting the price of a new medicine, Sanofi's decision 
making will continue to be guided by our pricing principles framework. 
When Sanofi sets the price of a new medicine in the U.S., we hold 
ourselves to a rigorous and structured process that includes 
consultation with external stakeholders. In our view, an objective 
measure of a new product's value considers the benefit to patients, 
compared to a standard of care; the reduced need--and therefore costs--
of other health-care interventions; and any increase in quality of life 
and productivity. We believe our pricing reflects these factors. We 
also consider factors such as the affordability for patients and any 
unique factors specific to the medicine, like the need to support 
ongoing clinical trials, implement important regulatory commitments, or 
develop sophisticated patient support tools that improve care 
management and help decrease the total cost of care.

    To the extent reform of the anti-kickback statute safe harbors 
results in changes in the competitive marketplace, patient access, and 
affordability, the rule is likely to affect our pricing of new 
medicines.

    Question. If the proposal is finalized and not extended to the 
private market, will your company make any list price reductions? If 
so, how large would the reductions be relative to the size of the 
rebates your company is currently providing?

    Answer. Sanofi is committed to working with other stakeholders to 
lower patient out-of-pocket costs, and the company will carefully 
review any final rule issued by HHS regarding the Anti-Kickback Statute 
and its safe harbor regulations--with the goal of providing point-of-
sale discounts to patients, in accordance with law, to lower their out-
of-pocket costs.

    Without addressing the currently misaligned incentives across all 
payer channels, it is unclear the extent to which Sanofi would be able 
to lower list prices. We would need a better understanding of how the 
rule ultimately would affect the competitive marketplace, patient 
access, and affordability in both the government and commercial 
insurance markets in order to quantify the amount of any potential list 
price reduction.

                                 ______
                                 
                Question Submitted by Hon. Maggie Hassan
    Question. In June of 2018, the Medicaid and CHIP Payment and Access 
Commission (MACPAC) unanimously recommended under Recommendation 1.1 in 
their annual report to Congress that Congress remove the statutory 
requirement that manufacturers blend the average manufacturer price 
(AMP) of a brand drug and its authorized generic.\33\
---------------------------------------------------------------------------
    \33\ MACPAC, ``Improving Operations of the Medicaid Drug Rebate 
Program,'' https://www.macpac.gov/wp-content/uploads/2018/06/Improving-
Operations-of-the-Medicaid-Drug-Rebate-Program.pdf.

    This requirement created an unintended loophole. Rather than use 
the price of the authorized generic, drug companies can sell its 
authorized generic to a corporate subsidiary at an artificially lower 
price, and use that lower price to bring down the AMP, which in turn 
---------------------------------------------------------------------------
lowers the rebate obligation.

    Does your company engage in this practice? Has your company ever 
engaged in this practice in the past?

    Answer. Sanofi currently markets authorized generic versions of 
certain of its products, through corporate affiliates, under separate 
National Drug Codes (``NDC''). Sanofi's general approach for these 
products has been that if two products share the same drug, dosage 
form, and strength, and both are sold by the same corporate entity or 
Sanofi business unit, then their sales are blended for the calculation 
of AMP and Best Price.

                                 ______
                                 
           Questions Submitted by Hon. Catherine Cortez Masto
    Question. In October you were asked by a reporter whether you would 
lower the price of insulin if point-of-sale rebates were enacted. Your 
response was, ``We realize that some medicines remain economically out 
of reach for some patients. We take this issue seriously and will 
continue to seek innovative solutions to help make insulins more 
affordable for patients.'' Please answer that question more 
specifically: will you lower your list price in response to the rebate 
rule?

    Answer. If (1) the proposed changes to the anti-kickback statute 
safe harbors were codified, and (2) Congress implemented similar 
changes to the commercial insurance market, Sanofi would lower the list 
prices of its prescription medications for products in competitive 
categories for which there is currently a material difference between 
list price and net price on the assumption that patient access and 
affordability would be improved. Sanofi also supports policy changes 
that would de-link other payments in the pharmaceutical supply chain 
from list price.

    We support extending the intent behind the anti-kickback statute 
safe harbor proposed rule to the commercial market so that incentives 
are aligned across the marketplace. Together, we believe these changes 
would facilitate Sanofi's ability to lower its list prices. However, we 
recommend a step-wise approach, implementing changes to the commercial 
market after the safe harbor rule is implemented on January 1, 2020. 
Such an approach would provide an opportunity for stakeholders and the 
government to identify unintended consequences, and address them, prior 
to extending these policies to the commercial market.

    We want to ensure that the new system achieves its goal of 
improving affordability for patients. For instance, CMS should monitor 
and evaluate how the new system affects formulary access, utilization 
management, and patient cost-sharing, particularly with respect to 
medicines with a lower list price. We also have concerns that changes 
to the rebate system may lead to new fees, which simply require 
manufacturers to pay previous rebate values in new ways, rather than 
creating savings for patients.

    Without a better understanding of how these policy changes 
ultimately would affect the competitive marketplace, patient access, 
and affordability, we are unable to quantify the amount of any 
potential list price reduction.

    Question. As a portion of your revenue, for what percentage of the 
drugs in your portfolio do you offer no rebates? Based on the drugs in 
your pipeline, do you foresee that portion growing? For those drugs is 
your list price equal to your net price?

    Answer. When considering rebates paid by Sanofi in any form, 
including those that are government-mandated, Sanofi offers rebates on 
all of its products at some point in the distribution channel. We do 
not expect that this will change based on the company's pipeline.

    Question. Do you invest more in R&D than you generate in U.S. sales 
revenue? Please include specific figures.

    Answer. In 2018, Sanofi spent $6,954,920,000 globally on R&D, a 7-
percent increase over 2017 and approximately 24 percent of its global 
gross profits. In 2018, Sanofi's U.S. net sales were $13,617,200,000.

    Answer. Do you invest more in R&D than you spend on marketing and 
administration? What company functions do you consider to be included 
in administration? Please include specific figures.

    Answer. Yes. In 2018, Sanofi spent $6,954,920,000 globally on R&D, 
and $6,921, 880,000 globally on marketing and administration. 
``Administration'' includes, but is not limited to: finance, human 
resources, external affairs, legal, business services, business 
development, and internal audit.

    Question. Do you invest more in R&D than you spend on marketing and 
sales? What company functions do you consider to be included in sales? 
Please include specific figures.

    Answer. In 2018, Sanofi spent $6,954,920,000 globally on R&D, and 
$8,154,980,000 globally on marketing and sales. The primary function 
included in ``sales'' is the sales force.

    Question. Why do you advertise for the drugs you manufacture? What 
factors do you consider in choosing which drugs you advertise?

    Answer. Sanofi believes that advertising is an important tool to 
inform and educate the public about its medicines, while raising 
general awareness of diseases that are frequently surrounded by stigma. 
We are committed to ensuring that our advertisements provide accurate, 
accessible, and useful health information to patients and consumers. 
Our communications are designed to educate patients and consumers about 
serious health conditions and the availability of treatments, and to 
encourage them to seek guidance from their healthcare professionals 
about appropriate treatment. We consider a variety of factors in 
determining whether and how to advertise a product, including patient 
needs and the unique aspects of an individual product or disease state.

                                 ______
                                 

                                      Independent Medical Education Grants
                                           1st Jan 2015-30th June 2015
    Sanofi US and its affiliate Genzyme Corporation are committed to supporting independent medical education
  activities in therapeutic areas in which the Company is involved, for healthcare professionals, patients, and
   consumers to improve patient care and health outcomes in therapeutic areas in which the Company is engaged.
        Sanofi US and Genzyme Corporation are part of the Sanofi Group, a global pharmaceutical company.
----------------------------------------------------------------------------------------------------------------
                                                                                                 Funding Amount
        Recipient Name(s) \1\                              Activity Title                             \2\
----------------------------------------------------------------------------------------------------------------
Academic CME, LLC Postgraduate         Incorporating Advancements in Monoclonal Antibody            $298,600.04
 Institute for Medicine                 Therapeutics into Patient Management Strategies                        Collaboration \3\
                                        within Dyslipidemia
 
Academy of Managed Care Pharmacy       The unmet needs of multiple sclerosis, and the                    $6,500
                                        principles and current evidence in the use of DMTs
 
Admin of the Tulane Educational Fund   7th Annual Tulane Symposium on Thyroid And Parathyroid        $10,000.00
 on behalf of TUHSC CCE                 Diseases                                                               Collaboration \3\
AKH Inc. Advancing Knowledge and       American Society for Preventive Cardiology: Annual            $10,000.00
 Healthcare                             Cardiovascular Disease Prevention Conference
 
American Academy of Physician          AAPA Conference 2015--Neurology Track                          $5,000.00
 Assistants
 
American Academy of Physician          AAPA Conference 2015--Endocrinology Track                      $5,000.00
 Assistants
 
American Academy of Physician          AAPA Conference 2015--Nephrology Track                         $3,500.00
 Assistants
 
American Association of Clinical       Georgia-AACE 2015 Annual Meeting                               $7,500.00
 Endocrinologists
 
American Association of Clinical       Lipids Sessions at Endocrine University: Disease               $5,000.00
 Endocrinologists                       Management and Technology Skills for Endocrinology
                                        Fellows In Training
 
American Association of Clinical       Southern States--AACE 2015 Annual Meeting                      $7,500.00
 Endocrinologists
 
American Association of Clinical       Diabetes Sessions At Endocrine University: Disease            $25,000.00
 Endocrinologists                       Management and Technology for Endocrinology Fellows
                                        in Training
 
American Association of Clinical       AACE 24th Annual Scientific & Clinical Congress               $47,350.00
 Endocrinologists                       (Thyroid Sessions)
 
American Association of Clinical       AACE 24th Annual Scientific & Clinical Congress               $47,350.00
 Endocrinologists                       (Diabetes Session)
 
American Association of Clinical       Diabetes Sessions at AACE 24th Annual Scientific And          $47,350.00
 Endocrinologists                       Clinical Congress
 
American Association of Clinical       Mid Atlantic Chapter of The American Association of            $7,500.00
 Endocrinologists                       Clinical Endocrinologists 13th Annual Meeting &
                                        Symposium
 
American Association of Clinical       Mid Atlantic Chapter of the American Association of            $7,500.00
 Endocrinologists                       Clinical Endocrinologists 13th Annual Meeting 7
                                        Symposium
 
American Association of Clinical       California Chapter of The American Association of             $20,000.00
 Endocrinologists                       Clinical Endocrinologists Presents: Hot Topics in
                                        Diabetes and Endocrinology for Primary Care
 
American Association of Clinical        LDL-C Reduction in the High-Risk Patient: How Low           $261,057.00
 Endocrinologists Medtelligence, LLC    Should We Go?                                                          Collaboration \3\
 
Association of Diabetes Educators      Diabetes Education and People with Diabetes: Partners         $15,000.00
                                        in the Winners Circle, New York American State
                                        Regional Conference
 
American Association of Diabetes       AADE 2015--Rumor has It? Demystifying the Use of Basal       $321,895.00
 Educators                              Insulin in Type 2 Diabetes Management
 
American College of Cardiology         ACC Rise and Shine Series: Just The Facts--An                 $55,000.00
 Foundation                             Objective Overview of PCSK9 Inhibitors                                 Collaboration \3\
 
American College of Cardiology          Lipid Management Today: Unanswered Questions and            $125,000.00
 Foundation Med-IQ, LLC                 Unquestioned Answers                                                   Collaboration \3\
 
American College of Surgeons American  36th Annual Meeting of the American Association of             $5,000.00
 Association of Endocrine Surgeons      Endocrine Surgeons
 
American Diabetes Association          2015 Professional Educator Conference                          $5,000.00
 
American Diabetes Association          ADA Inside: The Intelligent Use of Insulin Inspiring         $387,602.00
                                        System Improvement with Diabetes Education
 
American Diabetes Association          Diabetes is Primary                                          $166,545.00
 
American Health Resources, Inc.        Focus on the Patient with Diabetes: Managing Co-               $6,000.00
                                        Morbidities and Improving Outcomes
 
American Health Resources, Inc.        Identification and Resolution of Injection Technique          $12,600.00
                                        Barriers in Patients with Diabetes
 
American Nephrology Nurses'            The Questions, Myths, and Facts Regarding the                $160,000.00
 Association Rockpointe Corporation     Management Of CKD-MBD
 
American Neurological Association      2015 American Neurological Association 140th Annual           $25,000.00
                                        Meeting
 
American Society of Nephrology         ASN Highlights 2015                                           $15,000.00
 
American Society of Nephrology         AST/ASN Transplant Nephrology Core Curriculum                 $15,000.00
 
Ann & Robert H. Lurie Children's       Lysosomal Storage Disease Training Program for Genetic        $75,000.00
 Hospital of Chicago                    Counselors
 
Annenberg Center for Health Sciences   Diabetes Monitor Conference Coverage (ADA 2015)               $50,000.00
 at Eisenhower
 
Association of Black Cardiologists,    Lipid Management and Cardiovascular Risk Reduction:          $380,000.00
 Inc. National Association for          The Evolving Treatment Paradigm                                        Collaboration \3\
 Continuing Education
 
Association of Family Practice         Chronic Kidney Disease                                         $4,000.00
 Physician Assistants
 
Association of Family Practice         Joint Injection                                                $6,100.00
 Physician Assistants
 
Association of Family Practice         Diabetes--What Do I Prescribe After Metformin?                 $3,150.00
 Physician Assistants
 
Baylor University Medical Center dba   New Treatment Paradigms for Castrate Resistant                $15,330.00
 A. Webb Roberts Center CancerNet,      Prostate Cancer
 LLC
 
Baylor University Medical Center dba   New Treatment Paradigms for Castrate Resistant                $15,330.00
 A. Webb Roberts Center CancerNet,      Prostate Cancer
 LLC
 
BIDDM                                  Beth Israel Deaconess Medical Center Renal Division            $5,500.00
                                        Grand Rounds and Renal Biology Conference Series
 
Board of Regents of the University of  18th Annual Primary Care Update                                $6,000.00
 Oklahoma Health Science
 
Brigham and Women's Hospital Workshop  Kidney Disease Screening And Awareness Program (KDSAP)        $29,000.00
                                        New Chapters Training Workshop
 
California Academy of Family           The Family Medicine Clinical Forum                            $20,000.00
 Physicians
 
Cardiovascular Institute of Sarasota   11th Annual Cardiovascular Symposium Cardiology Update        $10,000.00
 Foundation for Education Florida       2015: Time to Focus on Early Cardiovascular Disease                    Collaboration \3\
 Medical Association                    Prevention
 
Children Health and Research           Fellowship in Inherited Metabolic Disorders and               $75,000.00
 Foundation, Inc.                       Lysosomal Storage Disorders
 
Children's Hospital of Philadelphia    Genetic Counselor Fellowship in lysosomal storage             $75,000.00
 Foundation                             disorders
 
Cincinnati Children's Hospital         Genetic Counseling Fellowship in the Lysosomal Storage        $74,987.00
 Medical Center                         Disorders
 
Cleveland Clinic Educational           Nephrology Update2015                                         $10,000.00
 Foundation
 
Cleveland Clinic Educational           Diabetes and Thyroid Update--A Multidisciplinary              $10,000.00
 Foundation                             Symposium on Diabetes and Thyroid Diseases
 
Cleveland Clinic Educational           2015 Diabetes Day 20th Annual Symposium: Diabetes             $10,000.00
 Foundation                             Through The Ages
 
Cleveland Clinic Educational           18th Annual Intensive Review of Endocrinology and             $20,000.00
 Foundation                             Metabolism
 
Cleveland Clinic Educational           Mellen Center Update In Multiple Sclerosis                     $5,000.00
 Foundation
 
Colorado Foundation for Medical Care   3rd Annual Convention of The Cardio Renal Society of          $30,000.00
 Cardio Renal Society of America        America
 
CME Outfitters, LLC                    Risky Business: Understanding and Attenuating Risk           $207,090.00
                                        Associated with Disease-Modifying Therapy in
                                        Relapsing-Remitting Multiple Sclerosis
 
Consortium of Multiple Sclerosis       Expert Debates in Multiple Sclerosis: Opposing Views         $125,000.00
 Centers                                in Management
 
Consortium of Multiple Sclerosis       PatientGPS TM: Clinical Paths to Explore Treatment           $100,000.00
 Centers                                Options and Individualize Therapy in Multiple
                                        Sclerosis
 
Consortium of Multiple Sclerosis       A Practical Guide to Rehabilitation in MS (an AIMS           $190,765.00
 Centers                                Primer)
 
Creative Educational Concepts, Inc.    Achieving Equilibrium in Diabetes with GLP-1 Receptor        $142,875.00
                                        Agonists: Avoiding Hypoglycemia When Treating
                                        Postprandial Hyperglycemia
 
Duke University                        Residency in Medical Genetics                                 $70,853.52
 
Educational Concepts Group, LLC        Advances in The Management Of GU Cancers: Highlights          $22,000.00
                                        From the 2015 Genitourinary Cancers Symposium
 
Educational Review Systems National    Effective Management of Gaucher Disease? A Primer for         $35,000.00
 Home Infusion Association              Home and Specialty Infusion Clinicians
 
Emory Genetics Laboratory              Multidisciplinary Extramural LSD Educational Talks on         $24,200.00
                                        Lysosomal Storage Diseases
 
Emory Genetics Laboratory              The Paul M. Fernhoff Genetic Counseling Fellowship in         $75,000.00
                                        the Lysosomal Storage Disorders
 
Emory University                       Emory Latino Diabetes Education Program                      $241,455.00
 
Endometriosis Association Inc.         Adhesion Awareness for Doctors and Patients:                  $54,591.48
                                        Communicating the Significance of Adhesion Disease
 
Fabry Support & Information Group      Eyes On Fabry-Illinois College of Optometry--Chicago           $2,550.00
 
Fabry Support & Information Group      Eyes on Fabry Southern College of Optometry Memphis,           $2,500.00
                                        TN
 
Florida Academy of Physician           The Good, the Bad, and the Latrogenic: Renal                   $9,000.00
 Assistants                             Medication Dosing?
 
Foundation for Care Management         Diabetes Mellitus: Detecting and Treating Type I & II         $50,000.00
                                        Patients in a Type II Global Epidemic
 
Glens Falls Association for the Blind  Interesting Cases - Lessons Learned the Hard Way              $23,352.24
 
Horizon CME, Inc.                      PCSK9 Inhibitors: Where Do They Fit in The Treatment         $163,300.00
                                        of Dyslipidemia?                                                       Collaboration \3\
 
Hospital for Special Surgery           Neurological Directions 2015: Update in Neuromuscular          $5,000.00
                                        Medicine
 
Humboldt-Del Norte Consortium for      Multiple Sclerosis                                             $4,100.00
 Continuing Medical Education
 
Icahn School of Medicine at Mount      Multiple Sclerosis and its Mimics                              $1,920.00
 Sinai
 
Imedex, LLC                            Unraveling The Complexities of Treating Metastatic           $198,856.00
                                        Colorectal Cancer with Anti-Angiogenesis Agents                        Collaboration \3\
                                        Across Multiple Lines of Therapy
 
Institute for Medical and Nursing      New Developments in Insulin Therapy: Expert Answers To       $222,519.33
 Education                              Your Clinical Questions--A Regional Meeting Series
 
Johns Hopkins University               The 11th Annual Johns Hopkins Multiple Sclerosis             $210,000.00
                                        Symposium Series
 
Johns Hopkins University Advanced      The Future of Lipid Management: New Perspectives &           $174,400.00
 Studies in Medicine                    Targets For LOWERING LDL-C
 
Johns Hopkins University Medical       Innovations in Prandial Glucose Control for Patients         $133,000.00
 Logix, LLC                             with Type 2 Diabetes
 
Kidneys for Life Fund Raising for      4th Update on Fabry Nephropathy; Manchester UK, June 1-       $75,000.00
 MINT                                   2, 2015
 
Joslin Diabetes Center, Inc.           Complementary Treatments To Enhance Insulin Efficacy:        $392,463.00
 Integrated Learning Partners, LLC      Theory And Strategies
 
Letters & Sciences University of       MS Leadership Summit 2015-2016                               $205,000.00
 North Texas Health Science Center at
 Fort Worth
 
Medical Education Resources CMEology,  Shifting the Treatment Paradigm for Multiple                 $100,000.00
 LLC                                    Sclerosis: Advances in Pathophysiology and Emergence
                                        of Novel Disease Modifying Therapies
 
Medical Education Resources Tarsus     Best of the Cardiometabolic Health Congress: Regional         $80,000.00
 Cardio Inc. dba Health Science Media   Conference Series and Virtual Highlights Activity
                                        with Extended Distribution on Medscape Education
 
Medical Education Resources Tarsus     Best of the Cardiometabolic Health Congress: Regional         $65,000.00
 Cardio Inc. dba Health Science Media   Conference Series and Virtual Highlights Activity
                                        with Extended Distribution on Medscape Education
 
Medical Education Resources Tarsus     Novel Therapies for LDL-C Lowering in the Fight              $250,000.00
 Cardio Inc. dba Health Science Media   Against Residual ASCVD Risk
 
Medical Learning Institute, Inc.       Understanding the Evolution of MS Care: Optimizing            $43,186.00
                                        Therapeutic Decision Making
 
Medical University of South Carolina   10th Annual Symposium on the Nephrology Update for             $2,500.00
                                        Primary Care and Hospital Medicine
 
Med-IQ, LLC                            The Top 10 Challenges in Managing High Risk Prostate         $192,276.00
                                        Cancer
 
Med-IQ, LLC                            Advancing the Management of Gaucher's Disease                $200,957.00
 
Med-IQ, LLC                            The Evolving Therapeutic Landscape In Gaucher's              $147,963.00
                                        Disease
 
Med-IQ, LLC                            The Evolution of Science, Medicine and Patient               $315,090.00
                                        Centered Care in CKD-MBD
 
Med-IQ, LLC                            Medical Insiders: Emerging Science for the Management        $100,000.00
                                        of Metastatic Castration-Resistant Prostate Cancer
 
Med-IQ, LLC                            Moving Beyond the Guidelines in the Management of            $135,207.00
                                        Castration-Resistant Prostate Cancer
 
Med-IQ, LLC                            New Horizons In Dyslipidemia Management: An                  $121,862.00
                                        Interactive Digital Publication                                        Collaboration \3\
 
Med-IQ, LLC Taking Control of Your     New and Emerging Insulins: The Top 10 Things You Need        $568,909.00
 Diabetes                               to Know About Biosimilars and Other Novel Insulins on
                                        the Therapeutic Horizon
 
Med-IQ, LLC Taking Control of Your     Practical Strategies to Address Postprandial                 $722,362.00
 Diabetes                               Hyperglycemia in Type 1 and Type 2 Diabetes: An                        Collaboration \3\
                                        Important Aspect of Overall Diabetes Care
 
Med-IQ, LLC Taking Control of Your     Making the Connection: Advancing Clinical Care and           $200,000.00
 Diabetes                               Improving Adherence for Patients with Diabetes
 
Medscape, LLC                          Advances in Ultra Rapid-Acting Insulin                       $732,600.00
 
Medscape, LLC                          A Balancing Act in CKD-MBD: Managing Hyperphosphatemia       $377,300.00
                                        and Cardiovascular Disease
 
Medscape, LLC                          Anti-Vegf Therapy in Metastatic Colorectal Cancer:            $99,000.00
                                        Where Are We and What Do We Know?                                      Collaboration \3\
 
Medscape, LLC                          The Future of Basal Insulin: Improving Patient               $200,000.00
                                        Outcomes by Addressing Unmet Needs
 
Medscape, LLC                          Combination Therapy in The Modern T2D Era                    $170,000.00
 
Medscape, LLC                          Long-Term Efficacy and Safety of Phosphate Binders for       $209,500.00
                                        Hyperphosphatemia in CKD-MBD
 
Medscape, LLC                          Comprehensive Management of CKD-MBD: Hands-on Case           $192,000.00
                                        Studies
 
Medscape, LLC                          An Update on LDL-C Management: Current Guidelines,           $450,000.00
                                        Treatment, and Future Recommendations
 
Medscape, LLC                          Highlights on Multiple Sclerosis Management From AAN         $100,000.00
                                        2015
 
Michigan Council of Nurse              Update in Arthritis Medication: Clearing Up the                $1,600.00
 Practitioners                          Confusion Michigan Council of Nurse Practitioners
                                        Annual Conference
 
Michigan State Medical Society         2015 Diabetes and Lipid Updates                                $5,000.00
 
Minnesota Optometric Association        Eyes on Fabry Minnesota Optometric Association's              $5,100.00
 Fabry Support & Information Group      Metro Society
 
Montefiore Medical Center              Multiple Sclerosis: Exploring Treatment Options and           $85,000.00
                                        Individualizing Therapy
 
National Association of Managed Care   Individualizing Treatment Strategies to Improve               $57,000.00
 Physicians, Inc.                       Patient Outcomes in the Management of Type 2 Diabetes
                                        (T2DM)
 
National Committee for Quality         Strategies for Success As A Patient-Centered Medical         $100,000.00
 Assurance (NCQA) Med-IQ, LLC           Home--Diabetes
 
National Committee for Quality         Strategies for Success As A Patient-Centered Medical         $250,000.00
 Assurance (NCQA) Med-IQ, LLC           Home--Dyslipidemia                                                     Collaboration \3\
 
National Comprehensive Cancer          NCCN 20th Annual Conference General Session: Advancing        $50,000.00
 Network, Inc.                          the Standard of Cancer CareTM
 
National Kidney Foundation             Getting Ahead of Metabolic and Mineral Disturbances in       $350,850.00
                                        the Management of CKD-MBD: A Focus on Management
                                        Strategies
 
National Kidney Foundation             Kidney Disease Outcomes Quality Initiative (KDOQI)            $10,000.00
                                        2015
 
National Kidney Foundation, Inc.       24th Annual Fellows Research Forum                             $5,000.00
 
National Kidney Foundation, Inc.       Charlotte Patient Empowerment Workshop                         $3,500.00
 
National Lipid Association             Lipid Academy Course Series of 3                              $15,000.00
 
National Lipid Association             Masters in Lipidology Course Series of 3                      $15,000.00
 
National Lipid Association             National Lipid Association's 2015 Scientific Meeting          $55,000.00
                                        Series
 
National Lipid Association             National Lipid Association's 2015 Scientific Meeting          $70,000.00
                                        Series                                                                 Collaboration \3\
 
National Lipid Association             2015 National Lipid Association's Masters in                  $30,000.00
                                        Lipidology and Lipid Academy Course Series                             Collaboration \3\
 
National Lipid Association Continuing  Dyslipidemia: New Challenges and Emerging Options in         $248,160.00
 Education Alliance, LLC                Lowering CVD RISK                                                      Collaboration \3\
 
National Tay-Sachs & Allied Diseases   NTSAD Science Symposium & Workshop For Researchers &          $10,000.00
 Association, Inc.                      Healthcare Professionals
 
Nebraska Academy of Physician          Renal Medication Dosing: The Good, the Bad and the             $4,000.00
 Assistants                             Latrogenic
 
New Jersey Academy of Family           The Future of Basal Insulin: Improving Patient               $399,550.00
 Physicians Medscape, LLC               Outcomes by Addressing Unmet Needs
 
New Mexico Optometric Association      Genetics, Gene Therapy and Stem Cell Therapy in Eye            $2,500.00
 Inc.                                   Care--The Future is Here
 
North American Center for Continuing   (CRS 2015) Therapeutic Advances in                           $310,100.00
 Medical Education, LLC Horizon CME,    Hypercholesterolemia: Examining the Role of PCSK-9                     Collaboration \3\
 Inc.                                   Inhibitors in Addressing Unmet Needs
 
North American Center for Continuing   Overcoming Systemic Barriers To Optimized                    $274,805.00
 Medical Education, LLC Horizon CME,    Hematopoeitic Stem Cell Transplants
 Inc.
 
Nurse Practitioner Alternatives        Caring for the Patient 2015                                  $118,400.00
 International Organization of
 Multiple Sclerosis Nurses
 
Oakstone Publishing, LLC PeerVoice     When Statins Are Not Enough: State of the Science in         $256,350.00
 America Limited                        Targeting Residual CV Risk                                             Collaboration \3\
 
Ohio State University                  Neuromuscular Fellowship Program                              $75,000.00
 
Penn State University Antidote         15th Annual Diabetes Symposium                                $18,000.00
 Education Company
 
Penn State University PeerView         Peerview Inplay: ``A Game-Based Approach to Patient-         $199,300.00
 Institute for Medical Education,       Centered Hypercholesterolemia Management''                             Collaboration \3\
 Inc.
 
Penn State University PeerView         Peerview Video In session, ``Approved Disease-               $139,375.00
 Institute for Medical Education,       Modifying Therapies For Multiple Sclerosis
 Inc.                                   Management: What Can We Learn From Recently Presented
                                        Data?''
 
Penn State University PeerView         Peerview Select-A-Scenario Live, ``Applying The Latest        $74,210.00
 Institute for Medical Education,       Evidence To Guide Treatment Decision-Making in CRPC:
 Inc.                                   Real Cases, Difficult Choices--You Make the Call''
 
Pharmacy Times Office of Continuing    Overcoming Challenges and Optimizing Insulin Therapy         $216,040.00
 Professional Education                 in Type 2 Diabetes
 
Pharmacy Times Office of Continuing    A Guide to Optimizing Insulin Therapy in Type 2              $175,730.00
 Professional Education                 Diabetes in the Managed Care Setting: Guidelines, New
                                        and Emerging Insulin Analogs, and Challenges in
                                        Management a Satellite Symposium at the 2015 AMCP
                                        Annual Meeting
 
Pharmacy Times Office of Continuing    Overcoming Challenges of Insulin Therapy in Type 2           $128,495.00
 Professional Education                 Diabetes: Exploring Emerging Options
 
Physicians' Education Resource, LLC    8th Annual Interdisciplinary Prostate Cancer Congress        $15,000.00
                                        and Other Genitourinary Malignancies
 
Postgraduate Institute for Medicine C- New Frontiers and Treatment Advances for Atopic              $350,000.00
 MEducation Resources, LLC              Dermatitis: Focus on the Role of Established and                       Collaboration \3\
                                        Evolving Biologic Therapies for Patients with
                                        Moderate-to-Severe and Treatment-Resistant Atopic
                                        Dermatitis
 
Postgraduate Institute for Medicine    20th Anniversary Scottsdale Prostate Cancer Symposium         $15,000.00
 Diversified Conference Management,
 Inc.
 
Postgraduate Institute for Medicine    Differentiating Therapeutic Approaches for Relapsing          $50,000.00
 Enquiring Minds LLC                    Multiple Sclerosis
 
Primary Care Education Consortium      Managing Postprandial Hyperglycemia in Type 2                $230,465.30
                                        Diabetes: Combining Basal Insulin and Glucagon-Like
                                        Peptide-1 Receptor Agonists
 
Primary Care Education Consortium      Strategies for Intensifying Insulin Management in Type       $275,955.15
                                        2 Diabetes
 
PRIME Education Inc. (PRIME)           Shifting Paradigms in Lipid Management                       $215,850.00
                                                                                                               Collaboration \3\
 
PRIME Education Inc. (PRIME)           New Therapies and Evidence for Patient-Centered              $205,000.00
                                        Hypercholesterolemia Care--Evolving Roles for                          Collaboration \3\
                                        Pharmacists
 
PRIME Education Inc. (PRIME)           Evidence-Based Decisions and a Mock P&T: The Role of         $161,020.00
                                        New LDL-C Reduction Therapy
 
Pri-Med Institute, LLC (d/b/a pmiCME)  Optimizing Insulin Therapy for Patients with Type 2          $805,275.00
                                        Diabetes: Existing Challenges and New Opportunities
                                        for Improved Care
 
Pri-Med Institute, LLC (d/b/a pmiCME)  Evolving Insulin Therapy: Optimizing Care Through            $812,950.00
 Horizon CME, Inc.                      Proper Selection & Use
 
Pri-Med Institute, LLC (d/b/a pmiCME)  Combining GLP-1 Receptor Agonists With Basal Insulin:        $797,090.00
 Horizon CME, Inc.                      Realizing the Potential in Type 2 Diabetes
 
ProCE, Inc.                            Safe Use of Concentrated Insulin: Helping Patients to         $87,575.00
                                        Get It Right
 
Purdue University Medikinetics LLC     Addressing Postprandial Glucose Excursions in Type 2         $363,648.00
                                        Diabetes with Inhaled Insulin
 
Purdue University PeerView Institute   Peerview Video Inexchange, ``Contemporary Multiple            $38,000.00
 for Medical Education, Inc.            Sclerosis Management: Identifying and Overcoming
                                        Challenges in the Managed Care Setting''
 
Regents of the University of           5th Annual UC Irvine Health Neuromuscular Colloquium          $20,000.00
 California
 
Regents of the University of Colorado  Practical Ways to Achieve Targets in Diabetes Care           $200,000.00
 
Regents of the University of Colorado  Aspen Lung Conference Asthma 2015: Mechanisms to               $5,000.00
                                        Personalized Medicine/Thomas Petty Aspen Lung                          Collaboration \3\
                                        Conference
 
Regents of the University of           Pharmacotherapy of Inherited Metabolic Diseases PharmD        $75,000.00
 Minnesota                              Post-Doctoral Fellowship
 
Regents of the University of           Transplant Immunosuppression 2015: Improving Outcomes         $50,000.00
 Minnesota
 
Research To Practice                   Data + Perspectives: Clinical Investigators Review Key       $100,000.00
                                        Publications And Current Cases in Advanced Prostate
                                        Cancer? An Independent Satellite Symposium (ISS)
                                        Series Held as Ancillary Events During The 2015
                                        Genitourinary Cancers Symposium
 
Rush University Medical Center         Rush University Medical Center Thyroid Cancer                 $20,000.00
                                        Symposium
 
Saint Joseph's Regional Medical        Chronic Kidney Disease for the Excellent Internist             $2,700.00
 Center
 
Saint Louis University School of       Role of Inflammation in Neurologic & Psychiatric               $5,850.00
 Medicine                               Diseases: Implications for Clinical Practice
 
Scripps Health                         Type 2 DM-Emerging Therapeutic Trends in OADS and            $330,257.00
                                        Insulin Combinations 2015: ADA Symposium
 
Scripps Health                         Scripps' 35th Annual Conference: Clinical Hematology          $15,000.00
                                        and Oncology 2015
 
Scripps Health                         Advanced Therapeutic Interventions to Optimize Obesity        $50,000.00
                                        and DM Care
 
Scripps Health                         Emerging Therapeutic Trends to Optimize Diabetes Care         $50,000.00
 
Society for Urologic Nurses and        Expert Perspectives in Advanced Prostate Cancer:              $30,000.00
 Associates (SUNA) Plexus               Practical Issues And Considerations for Nurses
 Communications
 
Southeastern Regional Genetics         Lysosomal Storage Disease Workgroup Meeting                    $2,000.00
 Groups, Inc. (SERGG)
 
Southern Alliance for Physician        Comprehensive Management of Thyroid and Parathyroid            $8,500.00
 Specialties CME                        Diseases
 
St. Dominic-Jackson Memorial Hospital  Managing the Diabetes Spectrum in the Pediatric and           $10,000.00
                                        Adult Populations: Pre-Diabetes, Type 1 and Type 2
 
Stony Brook University                 Hands on Cadaver Training in Colon And Rectal Diseases         $5,000.00
                                        Robotics, Laparoscopy, Endoscopy, Abdominal Wall
                                        Reconstruction
 
Swedish Medical Center Foundation      Thyroid Cancer and Parathyroid Disease - A Practical           $8,000.00
                                        Approach
 
Texas Academy of Family Physicians     Management of Chronic Kidney Disease in Primary Care           $3,000.00
                                        At The 2015 C. Frank Webber Lectureship
 
The Board of Trustees of the           Fabry Nephrology Fellowship                                   $75,000.00
 University of Alabama for the
 University of Alabama at Birmingham
 
The Board of Trustees of the UA for    Mini-Symposium on Fabry Disease: Prospects for                $17,536.00
 the UA at Birmingham                   Improved Care
 
The Children's Mercy Hospital          12th Annual Great Plains Pediatric and Adult Endocrine         $3,000.00
                                        Symposium
 
The Endocrine Society                  Overcoming Barriers in Diabetes Management with              $512,978.00
                                        Individualized Treatment Strategies
 
The Endocrine Society                  PCSK9 Inhibition--A Revolution in Cholesterol Therapy        $272,029.00
                                                                                                               Collaboration \3\
 
The Endocrine Society                  Endo 2015 Thyroid Cancer Sessions                             $73,000.00
                                                                                                               Collaboration \3\
 
The Endocrine Society                  Endo 2015 Diabetes Sessions                                   $50,000.00
 
The Endocrine Society                  Maximizing Benefits of Incretin-Based Therapy in Type        $135,056.00
                                        2 Diabetes
 
The Endocrine Society American         Diabetes Masters Series 2015--Solving The Puzzle:            $235,867.00
 Association of Diabetes Educators      Current Approaches to Providing Quality T2DM Care
 
The France Foundation American         Diabetes: Making the Right Choice in a Sea of                $121,080.00
 Academy of Physician Assistants        Treatment Options
 
The France Foundation                  MS Clinical Dialogs: A Peer Discussion on Optimal             $76,547.00
                                        Treatment (Phase 2)
 
The Medical College of Wisconsin,      The Eighth Annual Diabetes Symposium of Wisconsin              $5,000.00
 Inc.
 
The Ohio State University,             Endocrine Update 2015                                         $10,000.00
 
The University of Texas MD Anderson    6th Current Concepts in the Management of Thyroid &           $20,000.00
 Cancer Center                          Parathyroid Neoplasms
 
The University of Texas Southwestern   37th Annual Carrell-Krusen Neuromuscular Symposium            $20,000.00
 Medical Center at Dallas
 
The University of Texas Southwestern   Neuromuscular Medicine Fellowship                             $74,100.00
 Medical Center at Dallas
 
The University of Toledo               Outcomes of Myeloma: The Optimizing Sequenxe of                $3,000.00
                                        Treatments Including Transplant
 
Trustees of Columbia University in     Renal Biopsy in Medical Diseases of the Kidneys                $3,500.00
 the City of New York
 
UC Regents                             Diabetes Update and Advances In Endocrinology And              $7,500.00
                                        Metabolism
 
UC Regents                             LSD Genetic Counseling Fellowship                             $75,000.00
 
Ultimate Medical Academy, LLC dba      Cutting Edge Of Transplantation 2015                          $30,000.00
 Global Education Group American
 Society of Transplantation
 
University of California Irvine        Genetic Neuromuscular Diseases Fellowship                     $75,000.00
 
University of California, San Diego    34th Annual Advanced Nephrology: Nephrology for the           $10,000.00
                                        Consultant
 
University of California, San Diego    20th International Conference on Advances in Critical          $5,000.00
 CRRT Inc.                              Care Nephrology--AKI & CRRT 2015
 
University of Cincinnati CORE Medical  Navigating the Evolving Therapeutic Landscape in              $65,500.00
 Education, LLC.                        Advanced Prostate Cancer
 
University of Cincinnati Paradigm      Multidisciplinary Approach to Charting a Treatment            $94,650.00
 Medical Communications, LLC            Course for Men with Metastatic Castration-Resistant
                                        Prostate Cancer
 
University of Cincinnati Paradigm      Advancing Treatment Strategies in Metastatic                  $95,000.00
 Medical Communications, LLC            Castration-Resistant Prostate Cancer: The Urologist's
                                        Role
 
University of Florida                  Pediatric Neuromuscular Fellowship                            $75,000.00
 
University of Florida Foundation       Southern Salt, Water, and Kidney Club 56th Annual              $5,000.00
                                        Scientific Meeting
 
University of Kansas Endowment         Neuromuscular Review Course Series 2015                       $60,000.00
 Association
 
University of Massachusetts Medical    MS Practice Update: Managing Walking Impairment,              $30,000.00
 School                                 Neurogenic Bladder, Bowel and Sexual Dysfunction in
                                        Multiple Sclerosis
 
University of Massachusetts Medical    Understanding and Applying New Advances in Basal             $303,080.00
 School C-MEducation Resources, LLC     Insulin Therapy
 
University of Massachusetts Medical    The IQ&A Interactive Diabetes Intelligence Zone: Focus       $152,000.00
 School C-MEducation Resources, LLC     on Inhaled Insulin, Combination Regimens, and
                                        Postprandial Hyperglycemia
 
University of Massachusetts Medical    Novel Mechanisms and Advancing Therapeutic Paradigms         $336,000.00
 School C-MEducation Resources, LLC     for Optimizing LDL--Focused Management and                             Collaboration \3\
                                        Cardioprotection in the Diabetic Patient
 
University of Massachusetts Medical    New Frontiers and Treatment Advances for Atopic              $366,000.00
 School C-MEducation Resources, LLC     Dermatitis: Focus on the Role of Established and                       Collaboration \3\
                                        Evolving Biologic Therapies for Patients with
                                        Moderate-to-Severe and Treatment-Resistant Atopic
                                        Dermatitis
 
University of Massachusetts Medical    New Frontiers and Treatment Advances in Rheumatoid           $345,000.00
 School C-MEducation Resources, LLC     Arthritis: Focus on Mechanisms of Action, Cytokine-                    Collaboration \3\
                                        Mediated Inflammation and the Evidence for Safe and
                                        Effective Therapy for RA Through Inhibition of the IL-
                                        6 Cytokine and Other Signaling Systems
 
University of Massachusetts Medical    Novel Mechanisms and Advancing Therapeutic Paradigms         $465,900.00
 School C-MEducation Resources, LLC     for Optimizing LDL-Focused Management of Primary and                   Collaboration \3\
                                        Familial Hypercholesterolemia
 
University of Massachusetts Medical    Understanding and Applying New Advances in Basal             $971,000.00
 School C-M Education Resources, LLC    Insulin Therapy
 
University of Massachusetts Medical    New Frontiers and Emerging Treatment Paradigms for           $347,000.00
 School C-MEducation Resources, LLC     Optimizing LDL-Targeted Cardiovascular Risk Reduction                  Collaboration \3\
 
University of Miami                    Pediatric Nephrology Seminar XLII and Renal Pathology         $10,000.00
                                        Course
 
University of Pittsburgh               Seventh Annual Multidisciplinary Thyroid Cancer                $3,250.00
                                        Symposium: Integrating the New ATA Guidelines into
                                        Clinical Practice
 
University of Rochester, School of     2015 Society for Investigative Dermatology Annual             $10,000.00
 Medicine and Dentistry Society of      Meeting                                                                Collaboration \3\
 Investigative Dermatology
 
University of Southern California      37th Thyroid Symposium 2015: Practical Solutions To           $10,000.00
                                        Complex Clinical Problems
 
University of the Pacific Horizon      Basal Insulin Therapy in the Treatment of Insulin            $223,275.00
 CME, Inc.                              Resistant Type 2 Diabetes: The Role of the Pharmacist
                                        in Ensuring Their Safe and Effective Use
 
University of Virginia                 The 39th Annual Fitz-Hugh Symposium: Contemporary             $10,000.00
                                        Management and Cutting Edge Advances in
                                        Otolaryngology--Head & Neck Surgery (Special Emphasis
                                        on Laryngology and Head & Neck Endocrine Surgery)
 
USF Health Professions Conferencing    12th Annual Rocky Mountain Metabolic Syndrome                  $5,000.00
 Corporation CEConsultants, LLC         Symposium
 
VHA Inc.                               Treating Elevated LDL-C: Beyond Statins                       $85,000.00
                                                                                                               Collaboration \3\
 
Wellmont Health System                 13th Annual Diabetes Symposium                                 $4,000.00
 
Yale University                        Diabetes 2015                                                 $50,000.00
 
Yale University                        2015 New England Thyroid Club Program                         $10,000.00
----------------------------------------------------------------------------------------------------------------
\1\ Applicant names are provided by the requestor. If applicants apply as a group for a single educational
  activity; all applicants may be not be identified above. The Company funds other educational activities
  (including fellowships and non-physician and patient education); all of which do not appear on this report,
  but appear on other reports on this site.
\2\ ``Funding Amount'' is the amount that the Company funded during Q3, 2015 identified above based upon an
  agreement. Recipients are required to return any unused funds. Information on unused funds returned by the
  applicant on activities are not reported. ``Funding Amount'' does not include funds that may have been
  provided by other affiliated Sanofi Company Entities (e.g., Sanofi Pasteur).
\3\ Collaboration (Shared) Funding--is the full amount of a grant funded under an agreement with Regeneron, some
  or all of which may be shared between the collaborating entities.



                                      Independent Medical Education Grants
                                           1st Jul 2015-30th Sep 2015
    Sanofi US and its affiliate Genzyme Corporation are committed to supporting independent medical education
  activities in therapeutic areas in which the Company is involved, for healthcare professionals, patients, and
   consumers to improve patient care and health outcomes in therapeutic areas in which the Company is engaged.
        Sanofi US and Genzyme Corporation are part of the Sanofi Group, a global pharmaceutical company.
----------------------------------------------------------------------------------------------------------------
                                                                                                 Funding Amount
        Recipient Name(s) \1\                              Activity Title                           ($) \2\
----------------------------------------------------------------------------------------------------------------
Academic CME, LLC                      APPLYING ADVANCED TREATMENT STRATEGIES WITHIN                    326,430
                                        RHEUMATOID ARTHRITIS                                                   Collaboration \3\
 
AKH Inc. Advancing Knowledge and       FLORIDA SOCIETY OF RHEUMATOLOGY 2015 ANNUAL CME                    5,000
 Healthcare Florida Society of          CONFERENCE
 Rheumatology
 
American Academy of Continuing         TRANSLATING CLINICAL DATA INTO NEPHROLOGY PRACTICE IN            149,800
 Medical Education, Inc.                THE MANAGEMENT OF HYPERPHOSPHATEMIA
 
American Association of Clinical       HEARTLAND-AACE 6TH ANNUAL MEETING                                  7,500
 Endocrinologists
 
American Association of Clinical       ILLINOIS CHAPTER OF THE AMERICAN ASSOCIATION OF                    5,000
 Endocrinologists                       CLINICAL ENDOCRINOLOGISTS 5TH ANNUAL METING
 
American Association of Diabetes       INHALED INSULIN A BREATH OF FRESH AIR FOR THE                     62,800
 Educators Horizon CME, Inc.            TREATMENT OF DIABETES
 
American Diabetes Association          30TH ANNUAL CLINICAL CONFERENCE ON DIABETES: BEYOND               25,000
                                        THE NUMBERS
 
American Diabetes Association          DIABETES AND ENDOCRINE DISORDERS FOR THE GENERALIST                5,000
                                        AND SPECIALIST
 
American Diabetes Association          TRANSITIONS OF CARE THROUGH THE DIABETES LIFESPAN                  5,000
 
American Society of Nephrology         ASN BOARD REVIEW COURSE AND UPDATE                                15,000
 
American Society of Nephrology         CALCIUM OR NO CALCIUM: THAT IS THE QUESTION                      125,825
 
American Urological Association        ESTABLISHING AN ADVANCED PROSTATE CANCER CLINIC: A                60,000
 Education & Research, Inc.             PRACTICAL GUIDE FOR THE UROLOGY CLINIC
 
Association of Family Practice         JOINT ASPIRATION/INJECTION WORKSHOP                                5,300
 Physician Assistants
 
Cardiovascular Society of Buffalo and  UNDERSTANDIJG FABRY DISEASE FROM A CARDIAC PERSPECTIVE             7,000
 Western NY SUNY AT BUFFALO CME
 OFFICE
 
Cleveland Clinic Educational           CURRENT AND FUTURE THERAPEUTIC OPTIONS TARGETING                  80,000
 Foundation                             RESIDUAL CVD RISK: EMERGING THERAPIES FOR THE                          Collaboration \3\
                                        TREATMENT OF DYSLIPIDEMIA
 
CME Outfitters, LLC                    RISKY BUSINESS: UNDERSTANDING AND ATTENUATING RISK               207,090
                                        ASSOCIATED WITH DISEASE-MODIFYING THERAPY IN
                                        RELAPSING-REMITTING MULTIPLE SCLEROSIS
 
Consortium of Multiple Sclerosis       EXPERT DEBATES IN MULTIPLE SCLEROSIS: OPPOSING VIEWS             125,000
 Centers Nurse Practitioner             IN MANAGEMENT
 Alternatives
 
Consortium of Multiple Sclerosis       PATIENTGPS?: CLINICAL PATHS TO EXPLORE TREATMENT                 100,000
 Centers Nurse Practitioner             OPTIONS AND INDIVIDUALIZE THERAPY IN MULTIPLE
 Alternatives                           SCLEROSIS
 
Dignity Health MandatoryCE LLC         2ND ANNUAL NEW MEXICO REGIONAL DIABETES SYMPOSIUM                 45,000
 
FORE                                   2015 ORTHOPAEDICS FOR THE PRIMARY CARE PRACTITIONER &              4,000
                                        REHABILITATION THERAPIST
 
Humboldt-Del Norte Consortium for      MULTIPLE SCLEROSIS                                                 4,100
 Continuing Medical Education
 
Icahn School of Medicine at Mount      MULTIPLE SCLEROSIS AND ITS MIMICS                                  1,920
 Sinai
 
Icahn School of Medicine at Mount      ADVANCES IN PEDIATRIC FOOD ALLERGY                                15,000
 Sinai
 
Institute for the Advancement of       LEARNER-DIRECTED CME: WHAT DO PRIMARY CARE PROVIDERS              49,500
 Human Behavior Answers in CME, Inc.    NEED TO KNOW ABOUT THE LATEST ADVANCES IN THE
                                        TREATMENT HYPERCHOLESTEROLEMIA
 
Johns Hopkins University Advanced      THE 11TH ANNUAL JOHNS HOPKINS MULTIPLE SCLEROSIS                 210,000
 Studies in Medicine                    SYMPOSIUM SERIES
 
Johns Hopkins University Advanced      COMPREHENSIVE CARE FOR PATIENTS WITH GAUCHER DISEASE:            195,100
 Studies in Medicine                    EMERGING CONCEPTS FOR IMPROVED OUTCOMES
 
Johns Hopkins University Medical       MANAGEMENT OF PERSISTENT HYPERGLYCEMIA IN TYPE 2                  81,750
 Logix, LLC                             DIABETES: BEYOND STARTING DOSES OF BASAL INSULIN
 
Medical Education Resources Tarsus     THE EVOLUTION OF INSULIN THERAPY: NEW DEVELOPMENTS IN            100,000
 Cardio Inc. dba Health Science Media   TREATMENT, TECHNOLOGY, AND METHODS OF ADMINISTRATION
 
Medical Learning Institute, Inc.       PEERVIEW INREVIEW, RISING TO THE CHALLENGE: FOSTERING            100,000
 PeerView Institute for Medical         EFFECTIVE PATIENTPROVIDER COMMUNICATION THROUGHOUT
 Education, Inc.                        THE COURSE OF POMPE DISEASE
 
Medical University of South Carolina   1ST ANNUAL NEPHROLOGY TRANSPLANT SYMPOSIUM FOR                     2,500
                                        NEPHROLOGISTS, PRIMARY CARE AND HOSPITALISTS
 
Med-IQ, LLC                            TARGETING MODERATE-TO-SEVERE ATOPIC DERMATITIS:                   99,896
                                        EVOLVING TREATMENT STRATEGIES TO ADDRESS A KEY UNMET                   Collaboration \3\
                                        MEDICAL NEED
 
Med-IQ, LLC                            CASE SIMULATIONS IN TUMOR LYSIS SYNDROME: AGGRESSIVE             100,000
                                        PROPHYLAXIS STRATEGIES TO PREVENT ADVERSE PATIENT
                                        OUTCOMES
 
Med-IQ, LLC                            UPDATE FOR CLINICIANS: THE POTENTIAL OF IL-6                     104,578
                                        INHIBITORS TO REVOLUTIONIZE RHEUMATOID ARTHRITIS                       Collaboration \3\
                                        TREATMENT
 
Medscape, LLC                          A PRACTICAL GUIDE TO THE PREVENTION OF SURGICAL                  160,000
                                        ADHESIONS
 
Medscape, LLC                          IDENTIFYING AND ADDRESSING INADEQUATELY MANAGED                  138,500
                                        OSTEOARTHRITIS PAIN
 
Medscape, LLC                          GLP-1 RECEPTOR AGONISTS IN T2D MANAGEMENT: THE MODERN            105,100
                                        INJECTABLE
 
Missouri Academy of Physician          THE GOOD, THE BAD, AND THE IATROGENIC?                             3,500
 Assistants
 
Missouri Academy of Physician          JOINT INJECTIONS                                                   5,000
 Assistants
 
Montefiore Medical Center PlatformQ    A COMPREHENSIVE PERSPECTIVE ON INSULIN REPLACEMENT FOR           100,000
 Health Education, LLC                  TYPE 2 DIABETES
 
Montefiore Medical Center PlatformQ    MULTIPLE SCLEROSIS: EXPLORING TREATMENT OPTIONS AND               85,000
 Health Education, LLC                  INDIVIDUALIZING THERAPY
 
National Association of Managed Care   ADVANCES IN THE MANAGEMENT OF MULTIPLE SCLEROSIS: A               57,000
 Physicians, Inc.                       CLOSER LOOK AT NOVEL THERAPIES
 
National Association of Managed Care   INDIVIDUALIZING TREATMENT STRATEGIES FOR EFFECTIVE A1C            57,000
 Physicians, Inc.                       REDUCTION AND IMPROVED OUTCOMES IN TYPE 2 DIABETES
 
National Jewish Health California      CSAAI 23RD ANNUAL EDUCATIONAL MEETING                             10,000
 Society of Allergy, Asthma and                                                                                Collaboration \3\
 Immunology
 
National Kidney Foundation, Inc.       GREENSBORO PATIENT EMPOWERMENT WORKSHOP                            3,500
 
National Kidney Foundation, Inc.       CHRONIC KIDNEY DISEASE & THE PRIMARY CARE                         25,000
                                        PRACTITIONER: EARLY SCREENING AND PREVENTION FOR THE
                                        AT-RISK PATIENT
 
National Kidney Foundation, Inc.       11TH ANNUAL JOINT MEETING OF THE UPSTATE AND WESTERN               5,000
                                        NEW YORK COUNCILS ON RENAL NUTRITION
 
National Medical Association           NEW TYPE 2 DIABETES GUIDELINES AND THE TREND TOWARD              100,000
                                        NEWER PHARMACOLOGICAL TREATMENT
 
North American Center for Continuing   IMPLEMENTING BEST PRACTICES FOR TUMOR LYSIS SYNDROME             100,000
 Medical Education, LLC Horizon CME,
 Inc.
 
Not-For-Profit Hospital Corporation    CHRONIC KIDNEY DISEASE: STATE OF THE ART 2015                      1,900
 
Pennsylvania Academy of Family         PA ACADEMY OF FAMILY PHYSICIANS FOUNDATION A1C                   150,000
 Physicians Foundation                  CHALLENGE
 
Pennsylvania Society of Physician      THYROID MASSES                                                     8,400
 Assistants
 
Pharmacy Times Office of Continuing    CONVENIENT CARE OPPORTUNITIES TO OPTIMIZING INSULIN               48,689
 Professional Education                 THERAPY IN TREATMENT OF TYPE 2 DIABETES
 
Pharmacy Times Office of Continuing    AJPB QUALITY FORUM: IMPLEMENTATION OF QUALITY MEASURES            50,000
 Professional Education PQA, Inc.       TO IMPROVE OUTCOMES IN DYSLIPIDEMIA                                    Collaboration \3\
 
Pharmacy Times Office of Continuing    AJPB QUALITY FORUM: AIMING FOR A FIVE-STAR RATING IN              50,000
 Professional Education PQA, Inc.       DIABETES CARE: MANAGED CARE PLANS AND COMMUNITY
                                        PHARMACIST COLLABORATION
 
Postgraduate Healthcare Education,     ADDRESSING HYPOGLYCEMIA IN TYPE 2 DIABETES MELLITUS:              30,000
 LLC Medical Logix, LLC                 THE PHARMACISTS ROLE IN OPTIMIZING PATIENT OUTCOMES
 
Postgraduate Institute for Medicine C- NOVEL MECHANISMS AND ADVANCING THERAPEUTIC PARADIGMS             379,000
 MEducation Resources, LLC              FOR OPTIMIZING LDL-FOCUSED MANAGEMENT AND                              Collaboration \3\
                                        CARDIOPROTECTION IN THE DIABETIC PATIENT
 
Postgraduate Institute for Medicine C- THE IQ&A INTERACTIVE CARDIOVASCULAR INTELLIGENCE ZONE:           238,100
 MEducation Resources, LLC              NEW FRONTIERS IN LDL-TARGETED CV RISK REDUCTION                        Collaboration \3\
 
Preventive Cardiovascular Nurses       2015 FALL LEARNING SERIES                                         35,000
 Association
 
PRIME Education Inc. (PRIME)           CASE-BASED DEBATES ABOUT UTILITY OF PCSK9 INHIBITORS             123,000
                                        IN PATIENT POPULATIONS FOR LIPID REDUCTION                             Collaboration \3\
 
PRIME Education Inc. (PRIME)           INTERNATIONAL INSIGHTS ON TREATMENT ADVANCES FOR                 166,077
                                        RHEUMATOID ARTHRITIS                                                   Collaboration \3\
 
PRIME Education Inc. (PRIME)           NEW CHALLENGES IN THE PREVENTION AND MANAGEMENT OF                78,810
                                        TUMOR LYSIS SYNDROME IN PATIENTS WITH CHRONIC
                                        LYMPHOCYTIC LEUKEMIA
 
Pri-Med Institute, LLC (d/b/a pmiCME)  DYSLIPIDEMIA IN PRIMARY CARE: NEW GUIDELINE                      250,000
 Horizon CME, Inc.                      RECOMMENDATIONS AND TREATMENT OPTIONS                                  Collaboration \3\
 
ProCE, Inc. Institute for Safe         CONCENTRATED INSULIN: SAFE USE IN THE HOSPITAL AND               102,233
 Medication Practices                   TRANSITIONS OF CARE
 
Projects In Knowledge, Inc.            MULTIPLE SCLEROSIS @ POINT OF CARE                               200,000
 
Regents of the University of Colorado  RENAL DISEASE & ELECTROLYTE DISORDERS COURSE                       3,000
 
Regents of the University of Colorado  PEDIATRIC AND ADULT DIFFERENTIATED THYROID CANCER, ARE            75,000
 American Thyroid Association           THEY DIFFERENT?
 
Regents, University of California      THIRD ANNUAL UCLA REVIEW OF CLINICAL NEUROLOGY                    15,000
 
Rush University Medical Center Plexus  DEVELOPING AN INTEGRATIVE APPROACH TO METASTATIC                  65,000
 Communications                         PROSTATE CANCER: MAKING IT PERSONAL TO IMPROVE
                                        CLINICAL OUTCOMES
 
Rutgers, The State University of New   8TH ANNUAL PERSPECTIVES IN RHEUMATIC DISEASES,                    10,000
 Jersey Global Academy for Medical      PRESENTED BY RHEUMATOLOGY NEWS, INTERNAL MEDICINE                      Collaboration \3\
 Education, LLC                         NEWS, FAMILY PRACTICE NEWS
 
South Dakota Academy of Physician      DIABETIC MANAGEMENT                                                3,500
 Assistants
 
Tennessee Academy of Physician         FALLFEST 2015-RENAL DISEASE                                        2,500
 Assistants
 
Texas A&M University System Health     11TH ANNUAL DIABETES CONFERENCE                                   10,000
 Science Center Coastal Be
 
The Boston Home                        CARING FOR THE PATIENT WITH ADVANCED MULTIPLE                     10,000
                                        SCLEROSIS
 
The Endocrine Society                  UPDATE IN BASAL INSULINS: YOUR QUESTIONS ANSWERED                129,040
 
The Endocrine Society                  2015 CLINICAL ENDOCRINOLOGY UPDATE                                25,000
 
The Endocrine Society                  2015 CLINICAL ENDOCRINOLOGY UPDATE                                25,000
 
The France Foundation                  MS CLINICAL DIALOGS: A PEER DISCUSSION ON OPTIMAL                 76,547
                                        TREATMENT (PHASE 2)
 
The France Foundation National         A MULTI-DISCIPLINARY APPROACH TO LIMB-GIRDLE MUSCLE              240,794
 Society of Genetic Counselors          WEAKNESS DYSTROPHY AND RELATED CONDITIONS MANAGEMENT
 
The Medical College of Wisconsin,      INTERACTIVE UPDATES IN USE OF STEM CELL MOBILIZATION             120,000
 Inc. Carden Jennings Publishing Co.,   FOR THE TREATMENT OF BLOOD RELATED CANCERS
 Ltd.
 
Ultimate Medical Academy, LLC dba      IMPROVING OUTCOMES IN RHEUMATOID ARTHRITIS: TREATING             162,588
 Global Education Group Integritas      TO TARGET, IL-6-DIRECTED THERAPIES, AND EVOLVING                       Collaboration \3\
 Communications, LLC                    MANAGEMENT ALGORITHMS
 
UMA MLG, LLC                           THE CHANGING LANDSCAPE OF DYSLIPIDEMIA TREATMENT                 198,900
                                                                                                               Collaboration \3\
 
UMA MLG, LLC                           A 3-DIMENSIONAL VIEW INTO THE ROLE OF GLP1 IN TYPE-2              30,000
                                        DIABETES: EXPLORING EVIDENCE-BASED GUIDELINES AS
                                        PATIENT-CENTERED THERAPY
 
University of California, San Diego    PROMOTING BEHAVIOR CHANGE IN DIABETES: A SKILL                    50,000
 Behavioral Diabetes Institute          BUILDING PROGRAM FOR HEALTH CARE PROFESSIONALS A
 
University of Cincinnati Global        THE KNEE COURSE 2015                                              19,500
 Academy for Medical Education, LLC
 
University of Virginia Renal           RENAL PHYSICIANS ASSOCIATION 2015 ADVANCED                        12,500
 Physicians Association                 PRACTITIONER CONFERENCE
----------------------------------------------------------------------------------------------------------------
\1\ Applicant names are provided by the requestor. If applicants apply as a group for a single educational
  activity; all applicants may be not be identified above. The Company funds other educational activities
  (including fellowships and non-physician and patient education); all of which do not appear on this report,
  but appear on other reports on this site.
\2\ ``Funding Amount'' is the amount that the Company funded during Q3, 2015 identified above based upon an
  agreement. Recipients are required to return any unused funds. Information on unused funds returned by the
  applicant on activities are not reported. ``Funding Amount'' does not include funds that may have been
  provided by other affiliated Sanofi Company Entities (e.g., Sanofi Pasteur).
\3\ Collaboration (Shared) Funding--is the full amount of a grant funded under an agreement with Regeneron, some
  or all of which may be shared between the collaborating entities.


                                      Independent Medical Education Grants
                                           1st Oct 2015-31st Dec 2015
    Sanofi US and its affiliate Genzyme Corporation are committed to supporting independent medical education
  activities in therapeutic areas in which the Company is involved, for healthcare professionals, patients, and
   consumers to improve patient care and health outcomes in therapeutic areas in which the Company is engaged.
        Sanofi US and Genzyme Corporation are part of the Sanofi Group, a global pharmaceutical company.
----------------------------------------------------------------------------------------------------------------
                                                                                                 Funding Amount
        Recipient Name(s) \1\                              Activity Title                           ($) \2\
----------------------------------------------------------------------------------------------------------------
American Academy of Physician          2015 ADULT HOSPITAL MEDICINE BOOT CAMP                             2,500
 Assistants
 
American Association of Clinical       NEW ENGLAND CHAPTER OF AACE 7TH ANNUAL MEETING                     5,000
 Endocrinologists
 
American Association of Clinical       DIABETES DAY FOR PRIMARY CARE CLINICIANS EDUCATIONAL              50,000
 Endocrinologists                       SERIES
 
American Neurological Association      2015 AMERICAN NEUROLOGICAL ASSOCIATION 140TH ANNUAL               25,000
                                        MEETING
 
ANNA Chapter 125, 126, and 133         ANNA NJ COLLABORATIVE 2015                                         3,000
 
Annenberg Center for Health Sciences   INITIATING AND ADVANCING MULTIPLE SCLEROSIS THERAPIES:           125,000
 at Eisenhower Postgraduate Institute   IMPROVING PATIENT CARE AND HEALTH OUTCOMES
 for Medicine
 
Baylor University Medical Center dba   FOLLOWING THE EVIDENCE A PRACTICAL, CASE BASED                    45,975
 A. Webb Roberts Center MedNet, LLC     APPROACH TO PERSONALIZED TREATMENT OPTIONS FOR
                                        MULTIPLE SCLEROSIS
 
California Optometric Association      2015 MONTEREY SYMPOSIUM                                            7,416
 
Cedars-Sinai Medical Center            5TH ANNUAL SYMPOSIUM ON LYSOSOMAL STORAGE DISORDERS               26,010
 
Consortium of Multiple Sclerosis       4TH CONFERENCE OF THE INTERNATIONAL MS COGNITION                  56,280
 Centers Nurse Practitioner             SOCIETY IN COLLABORATION WITH THE CONSORTIUM OF
 Alternatives                           MULTIPLE SCLEROSIS CENTERS
 
Harris County Optometric Society       EYES ON FABRY HARRIS COUNTY OPTOMETRIC SOCIETY                     7,000
 Fabry Support & Information Group
 
Horizon CME, Inc.                      STRATEGIES FOR SELECTION AND OPTIMAL SEQUENCING OF                85,000
                                        CURRENT TREATMENT OPTIONS FOR METASTATIC CASTRATION-
                                        RESISTANT PROSTATE CANCER
 
Icahn School of Medicine at Mount      3RD NY MASTERS COURSE IN ENDOCRINOLOGY AND ENDOCRINE              15,000
 Sinai                                  SURGERY
 
Indiana Academy of Physician           THE GOOD, THE BAD AND THE IATROGENIC (RENAL MEDICATION             3,250
 Assistants                             DOSING)
 
Letters & Sciences                     ADVANCES IN MS RESEARCH & PRACTICE 2015 ANNUAL                    70,000
                                        CONFERENCE
 
Medical Education Resources Tarsus     2015 CMHC SYMPOSIUM: NOVEL THERAPIES FOR LDL-C                    40,000
 Cardio Inc. dba Health Science Media   LOWERING IN THE FIGHT AGAINST RESIDUAL ASCVD RISK
 
Medical Learning Institute, Inc.       PEERVIEW IN EXCHANGE, ESTABLISHING BEST PRACTICES FOR            140,325
 PeerView Institute for Medical         THE PERSONALIZED CARE OF PATIENTS WITH MULTIPLE
 Education, Inc.                        SCLEROSIS: A TIMELY DISCUSSION AMONG ADVANCED
                                        PRACTICE CLINICIANS?
 
Medical Learning Institute, Inc.       PEERVIEW VIDEO IN SESSION, CLINICAL HIGHLIGHTS FROM              134,450
 PeerView Institute for Medical         BARCELONA: AN UP-TO-DATE REVIEW OF NEW DATA ON
 Education, Inc.                        APPROVED DISEASE-MODIFYING THERAPIES FOR MULTIPLE
                                        SCLEROSIS MANAGEMENT?
 
Medical Learning Institute, Inc.       2016 ACMG--PEERVIEW LIVE, ENSURING THE RAPID                     239,950
 PeerView Institute for Medical         IDENTIFICATION AND INDIVIDUALIZED MANAGEMENT OF
 Education, Inc.                        GAUCHER DISEASE TYPE 1: KEY PRINCIPLES AND STRATEGIES
 
Med-IQ,                                LLC NEW THERAPIES FOR GAUCHER'S DISEASE: TALK TO YOUR            147,396
                                        PHARMACIST
 
Med-IQ, LLC                            EARLIER RECOGNITION AND TREATMENT OF GAUCHER'S DISEASE           135,728
                                        IN HEMATOLOGY CLINICS
 
Med-IQ, LLC                            RECOGNIZING THE UNLIKELY: IMPROVING IDENTIFICATION AND           246,977
                                        CARE OF FABRY DISEASE
 
Michigan State Medical Society         CARDIOVASCULAR DISEASE IN PATIENTS WITH RENAL DISEASE              2,500
 
National Jewish Health                 38TH ANNUAL PULMONARY AND ALLERGY UPDATE                          10,000
                                                                                                               Collaboration \3\
 
National Jewish Health Western         WSAAI 54TH ANNUAL SCIENTIFIC SESSION                              10,000
 Society of Allergy, Asthma and                                                                                Collaboration \3\
 Immunology (WSAAI)
 
National Kidney Foundation, Inc.       NATIONAL KIDNEY FOUNDATION'S 47TH ANNUAL MEDICAL                   2,500
                                        SYMPOSIUM
 
National Multiple Sclerosis Society    Research Symposium 2015: MS Research Discoveries:                  3,000
 New York Chapter                       Wellness and Treatments for Living Your Best Life
 
Pennsylvania Society of Physician      RENAL MEDICATION DOSING: THE GOOD, THE BAD, AND THE                4,000
 Assistants                             IATROGENIC
 
PESI, Inc. Metabolic Endocrine         13TH ANNUAL WORLD CONGRESS ON INSULIN RESISTANCE,                 15,000
 Education Foundation                   DIABETES AND CARDIOVASCULAR DISEASE--WCIRDC                            Collaboration \3\
 
Postgraduate Institute for Medicine    FAILURE IS NOT AN OPTION: SELECTING OPTIMAL STEM CELL            205,195
 AXIS Medical Education, Inc.           MOBILIZATION STRATEGIES FOR MULTIPLE MYELOMA AND NON-
                                        HODGKIN LYMPHOMA
 
Postgraduate Institute for Medicine    1,800 SECONDS? IN DIABETES MANAGEMENT WITH A GLP-1                75,000
 Catamount Medical Education, LLC       RECEPTOR AGONIST AND BASAL INSULIN
 
Projects In Knowledge, Inc. MedPage    CLINICAL CONTEXT: MULTIPLE SCLEROSIS                             131,000
 Today, LLC
 
Rutgers, The State University of New   THE FOURTH EVIDENCE-BASED PEDIATRIC UPDATE SYMPOSIUM               5,000
 Jersey
 
Rutgers, The State University of New   SKIN DISEASE EDUCATION FOUNDATION'S 16TH ANNUAL LAS                5,000
 Jersey Global Academy for Medical      VEGAS DERMATOLOGY SEMINAR, FEATURING THE 12TH ANNUAL                   Collaboration \3\
 Education, LLC                         PSORIASIS FORUM
 
Society of Nuclear Medicine            SNMMI 2015-2016 THYROID IMAGING AND THERAPY                      108,730
                                        EDUCATIONAL OUTREACH FOR REFING PHYSICIANS AND
                                        IMAGING PHYSICIANS
 
Swedish Medical Center Foundation      FIFTH ANNUAL INTENSIVE UPDATE IN NEUROLOGY                        10,000
 
Swedish Medical Center Foundation      DIABETES MANAGEMENT UPDATE 2015                                    8,000
 
The Board of Trustees of the UA for    SPECIAL NEPHROLOGY RESEARCH AND TRAINING CENTER                   15,000
 the UA at Birmingham                   SYMPOSIUM--11/9/15
 
The University of Texas Southwestern   NEUROTHERAPEUTICS UPDATE                                           5,000
 Medical Center at Dallas
 
Tufts University School of Medicine    IMPROVING CARE FOR HEART FAILURE PATIENTS: AN UPDATE               5,000
                                        FOR HEALTHCARE PROVIDERS - THE 8TH ANNUAL NEW ENGLAND
                                        HEART FAILURE AND TRANSPLANT NETWORK CONFERENCE
 
University of Massachusetts Medical    NEW FRONTIERS AND EMERGING TREATMENT PARADIGMS FOR               347,000
 School C-MEducation Resources, LLC     OPTIMIZING LDLTARGETED CARDIOVASCULAR RISK REDUCTION                   Collaboration \3\
 
University of Massachusetts Medical    THE IQ&A INTERACTIVE RHEUMATOID ARTHRITIS INTELLIGENCE           189,000
 School C-MEducation Resources, LLC     ZONE: FOCUS ON THE EVIDENCE BASIS FOR RA MANAGEMENT                    Collaboration \3\
                                        THROUGH INHIBITION OF THE IL-6 CYTOKINE AND OTHER
                                        FOUNDATION SIGNALING SYSTEMS
 
University of Massachusetts Medical    NEW FRONTIERS AND TREATMENT ADVANCES FOR ATOPIC                  360,000
 School C-MEducation Resources, LLC     DERMATITIS: FOCUS ON THE ROLE OF ESTABLISHED AND                       Collaboration \3\
                                        EVOLVING BIOLOGIC THERAPIES FOR PEDIATRIC AND ADULT
                                        PATIENTS WITH MODERATE-TO-SEVERE AND TREATMENT-
                                        RESISTANT ATOPIC DERMATITIS
 
University of Texas Health Science     AMDA INTERNATIONAL PATIENT AND SCIENTIFIC CONFERENCE--            60,000
 Center at San Antonio Acid Maltase     PAST, PRESENT, FUTURE
 Deficiency Association, Inc.
 
Vindico Medical Education, LLC         IN SEARCH OF THE GUIDING LIGHT: RE-VISITING THE USE OF           372,524
                                        ORAL AND HIGHEFFICACY THERAPIES IN A MODERN ERA OF
                                        MULTIPLE SCLEROSIS TREATMENT
 
----------------------------------------------------------------------------------------------------------------
\1\ Applicant names are provided by the requestor. If applicants apply as a group for a single educational
  activity; all applicants may be not be identified above. The Company funds other educational activities
  (including fellowships and non-physician and patient education); all of which do not appear on this report,
  but appear on other reports on this site.
\2\ ``Funding Amount'' is the amount that the Company funded during Q4, 2015 identified above based upon an
  agreement. Recipients are required to return any unused funds. Information on unused funds returned by the
  applicant on activities are not reported. ``Funding Amount'' does not include funds that may have been
  provided by other affiliated Sanofi Company Entities (e.g., Sanofi Pasteur).
\3\ Collaboration (Shared) Funding--is the full amount of a grant funded under an agreement with Regeneron, some
  or all of which may be shared between the collaborating entities.


                                      Independent Medical Education Grants
                                           1st Jan 2016-31th Mar 2016
    Sanofi US and its affiliate Genzyme Corporation are committed to supporting independent medical education
  activities in therapeutic areas in which the Company is involved, for healthcare professionals, patients, and
   consumers to improve patient care and health outcomes in therapeutic areas in which the Company is engaged.
        Sanofi US and Genzyme Corporation are part of the Sanofi Group, a global pharmaceutical company.
----------------------------------------------------------------------------------------------------------------
                                                                                                 Funding Amount
        Recipient Name(s) \1\                              Activity Title                           ($) \2\
----------------------------------------------------------------------------------------------------------------
Admin of the Tulane Educa Fund on      8TH ANNUAL TULANE SYMPOSIUM ON THYROID AND PARATHYROID             7,500
 behalf of TUHSC CCE                    DISEASES
 
AKH Inc Advancing Knowledge and        2016 SOUTH BEACH SYMPOSIUM: CLINICAL DERMATOLOGY                   5,000
 Healthcare                             SYMPOSIUM                                                              Collaboration \3\
 
AKH Inc Advancing Knowledge and        NOVEL MECHANISMS AND ADVANCING THERAPEUTIC PARADIGMS             336,000
 Healthcare C-MEducation Resources,     FOR OPTIMIZING LDLFOCUSED MANAGEMENT AND CV RISK                       Collaboration \3\
 LLC                                    REDUCTION IN THE DIABETIC PATIENT
 
American Academy of Continuing         INCREASING ACCESS TO KIDNEY TRANSPLANTATION: NOVEL               104,000
 Medical Education, Inc. Spire          STRATEGIES TO EXPAND LIVING DONATION
 Learning
 
American Association of Clinical       THYROID SESSIONS AT ENDOCRINE UNIVERSITYr: DISEASE                30,000
 Endocrinologists                       MANAGEMENT & TECHNOLOGY SKILLS FOR ENDOCRINOLOGY
                                        FELLOWS IN TRAINING
 
American Association of Clinical       NEVADA AACE THYROID CANCER SYMPOSIUM                               5,000
 Endocrinologists
 
American Association of Clinical       LDL-C REDUCTION IN THE PATIENT WITH DIABETES: HOW LOW            267,758
 Endocrinologists Medtelligence, LLC    SHOULD WE GO AND HOW SHOULD WE GET THERE?                              Collaboration\3\
 
American College of Cardiology         DYSLIPIDEMIA COMBO-THERAPY: A FRAMEWORK FOR CLINICAL              75,000
 Foundation                             DECISION-MAKING                                                        Collaboration\3\
 
American College of Rheumatology       2016 ACR RHEUMATOLOGY COURSES                                    150,000
                                                                                                               Collaboration \3\
 
American Health Resources, Inc.        EXAMINING THE ROLE OF PCSK9 INHIBITORS IN DYSLIPIDEMIA             4,200
                                        MANAGEMENT                                                             Collaboration \3\
 
American Kidney Fund                   AMERICAN KIDNEY FUND 2016 CLINICAL SCIENTIST IN                   75,000
                                        NEPHROLOGY PROGRAM
 
American Society of Transplant         ASTS 16TH ANNUAL STATE OF THE ART WINTER SYMPOSIUM:               50,000
 Surgeons                               LIMITED SUPPLY, INCREASING DEMAND: EXPANDING ORGAN
                                        DONATION
 
Annenberg Center for Health Sciences   EXPERTS IN RESIDENCE: BRIDGING THE GAP FROM KNOWLEDGE            110,000
 at Eisenhower                          TO PRACTICE IN CASTRATION-RESISTANT PROSTATE CANCER
 
Association of Black Cardiologists,    EVOLVING STRATEGIES FOR CARDIOVASCULAR RISK REDUCTION:           350,000
 Inc. National Association for          BEYOND STATIN THERAPY                                                  Collaboration \3\
 Continuing Education
 
Cardiovascular Center of Sarasota      12TH ANNUAL CARDIOVASCULAR SYMPOSIUM CARDIOLOGY UPDATE             5,000
 Foundation for Research and Florida    2016: FROM INTERVENTION TO PREVENTION TIME TO FOCUS                    Collaboration \3\
 Medical Association                    ON EARLY CARDIOVASCULAR HEALTH
 
Cardio Renal Society of America        4th ANNUAL CARDIO-RENAL METABOLIC CONFERENCE                       6,000
 
CME Outfitters, LLC                    IMPLEMENTING PERSONALIZED ACTION PLANS FOR PATIENTS             99,867.5
                                        WITH ATOPIC DERMATITIS                                                 Collaboration \3\
 
Consortium of Multiple Sclerosis       CLINICIAN-PATIENT SHARED DECISION MAKING IN MS: AN               100,860
 Centers Nurse Practitioner             ESSENTIAL STEP TOWARD BETTER OUTCOMES
 Alternatives
 
Emory University                       EVALUATION OF THE LGMD DIAGNOSTIC TESTING PROGRAM:                 5,850
                                        PROGRAM UPDATES, OPPORTUNITIES AND FUTURE WORK
 
Forefront Collaborative National       CURRENT CONTROVERSIES IN DYSLIPIDEMIA MANAGEMENT: A               85,000
 Lipid Association                      POINT-COUNTERPOINT DISCUSSION                                          Collaboration \3\
 
Medical Learning Institute, Inc.       UNDERSTANDING THE EVOLUTION OF MS CARE: OPTIMIZING                43,186
                                        THERAPEUTIC DECISION MAKING
 
Medical Learning Institute, Inc.       PEERVIEW INCLINIC, ``MAXIMIZING CARE FOR INDIVIDUALS             145,000
 PeerView Institute for Medical         WITH MULTIPLE SCLEROSIS: THE ROLE OF
 Education, Inc.                        INTERPROFESSIONAL EDUCATION''
 
Medical Learning Institute, Inc.       PEERVIEW LIVE, "DISRUPTING DISEASE WORSENING IN                  296,820
 PeerView Institute for Medical         PATIENTS WITH MS: HOW CAN WE HARNESS THE FULL
 Education, Inc                         POTENTIAL OF AVAILABLE DISEASE-MODIFYING
 
Med-IQ, LLC                            WHEN INSULIN ALONE ISN'T THE ANSWER: A FOCUSED LOOK AT           257,768
                                        COMBINING BASAL INSULIN AND GLP-1 RECEPTOR AGONISTS
 
Med-IQ, LLC                            HOW EARLY IS EARLY? WHEN TO START ERT AND OTHER                  160,522
                                        CONSIDERATIONS FOR OPTIMIZING TREATMENT OF FABRY
                                        DISEASE
 
National Association of Managed Care   EFFECTIVE A1C REDUCTION IN TYPE 2 DIABETES: A CLOSER              75,000
 Physicians, Inc.                       LOOK AT COMBINATION INSULIN THERAPY
 
National Kidney Foundation, Inc.       CKD-MBD: STATE-OF-THE-ART CONSIDERATIONS FOR OPTIMAL             253,850
 University of Illinois at Chicago      OUTCOMES
 
National Lipid Association             NATIONAL LIPID ASSOCIATION 2016 MASTERS IN LIPIDOLOGY             20,000
                                        COURSE SERIES                                                          Collaboration \3\
 
National Lipid Association             NATIONAL LIPID ASSOCIATION 2016 LIPID ACADEMY COURSE              20,000
                                        SERIES                                                                 Collaboration \3\
 
Nebraska Academy of Physician          JOINT INJECTION WORKSHOP                                           5,100
 Assistants
 
Nevada System of Higher Education      2016 WINTER CLINICAL DERMATOLOGY CONFERENCE--HAWAII               50,000
 Foundation for Research and                                                                                   Collaboration \3\
 Education in Dermatology
 
North American Center for Continuing   MEETING THE UNMET NEEDS OF PATIENTS WITH                         415,000
 Medical Education, LLC Horizon CME,    HYPERCHOLESTEROLEMIA: A FOCUS ON PCSK9 INHIBITORS                      Collaboration \3\
 Inc.
 
NYU School of Medicine                 SEMINAR IN ADVANCED RHEUMATOLOGY                                  20,000
                                                                                                               Collaboration \3\
 
NYU School of Medicine                 41ST ANNUAL COMPREHENSIVE REVIEW OF PHYSICAL MEDICINE              5,000
                                        AND REHABILITATION
 
Pharmacy Times Office of Continuing    COST-EFFECTIVENESS OF DISEASE-MODIFYING THERAPIES IN              89,160
 Professional Education                 MULTIPLE SCLEROSIS: A MANAGED CARE PERSPECTIVE
 
Pharmacy Times Office of Continuing    INNOVATION AND CLINICAL ADVANCES IN ACHIEVING GLYCEMIC           240,728
 Professional Education                 CONTROL: EVALUATING THE EFFICACY OF COMPLIMENTARY
                                        AGENTS
 
Pharmacy Times Office of Continuing    THE ROLE OF THE PHARMACIST IN ACHIEVING TIGHT GLYCEMIC            53,346
 Professional Education                 CONTROL IN TYPE 2 DIABETES: PROMOTING PATIENT SELF-
                                        MONITORING AND AGGRESSIVE TREATMENT
 
Physicians' Education Resource, LLC    2016 NEW YORK GUTM: 9TH ANNUAL INTERDISCIPLINARY                  75,000
                                        PROSTATE CANCER CONGRES
 
Postgraduate Healthcare Education,     OPTIMIZED APPROACHES TO INSULIN THERAPY AND GLUCOSE              301,000
 LLC                                    CONTROL IN TYPE 2 DIABETES
 
Postgraduate Institute for Medicine C- NEW THERAPEUTIC ADVANCES AND PRACTICAL STRATEGIES FOR            309,500
 MEducation Resources, LLC              COMPLEMENTARY BASAL INSULIN PLUS INCRETIN SYSTEM-
                                        TARGETED THERAPY TO OPTIMIZE GLUCOSE CONTROL
 
Postgraduate Institute for Medicine C- NEW THERAPEUTIC ADVANCES AND PRACTICAL STRATEGIES FOR            331,000
 MEducation Resources, LLC              COMPLEMENTARY BASAL INSULIN PLUS INCRETIN SYSTEM-
                                        TARGETED THERAPY IN COMPLEX PATIENTS WITH
 
Primary Care Education Consortium      COMBINING A GLUCAGON-LIKE PEPTIDE-1 RECEPTOR AGONIST             309,985
                                        WITH BASAL INSULIN: THE WHY AND HOW
 
PRIME Education Inc (PRIME)            NEW TREATMENT GUIDELINES, EVIDENCE, AND AGENTS IN                249,505
                                        RHEUMATOID ARTHRITIS                                                   Collaboration \3\
 
Pri-Med Institute, LLC (d/b/a pmiCME)  HOW TO SELECT AND INITIATE INSULIN THERAPY IN THE TYPE           998,500
 Horizon CME, Inc.                      2 DIABETES PATIENT
 
Pri-Med Institute, LLC (d/b/a pmiCME)  GLP-1 RECEPTOR AGONISTS AND BASAL INSULIN COMBINATION:           977,000
 Horizon CME, Inc.                      AN COMPLEMENTARY STRATEGY FOR TYPE 2 DIABETES
                                        TREATMENT INTENSIFICATION
 
Projects In Knowledge, Inc.            MEDIMAGE CASES: MULTIPLE SCLEROSIS                               125,000
 
Rhode Island Hospital, CME             ENDOCRINE GRAND ROUNDS                                            10,000
 
Rutgers, The State University of New   SKIN DISEASE EDUCATION FOUNDATION'S 40TH ANNUAL HAWAII            10,000
 Jersey Global Academy for Medical      DERMATOLOGY SEMINAR                                                    Collaboration \3\
 Education, LLC
 
ScientiaCME, LLC Specialty Pharma      PROSTATE CANCER: ADVANCES IN PATIENT MANAGEMENT &                 14,875
 Education Center                       TREATMENT OPTIONS
 
Scripps Health                         SCRIPPS WHITTIER DIABETES INSTITUTE'S PROJECT DULCE               50,000
 
The Endocrine Society Advanced         THE EFFECTIVE USE OF INSULIN IN TYPE 2 DIABETES: A               329,613
 Studies in Medicine                    FOCUS ON TREATMENT ADVANCES
 
The Endocrine Society Institute for    DIABETES MASTERS SERIES 2016: INITIATING THE                   237,055.5
 Medical and Nursing Education          CONVERSATION: SHARING PERSPECTIVES ON ADVANCES IN
                                        T2DM TREATMENT TO IMPROVE PATIENT-CENTERED CARE
 
The Endocrine Society Scripps Health   NEW COMPLEMENTARY INSULIN COMBINATIONS TO ACHIEVE                361,515
                                        HBA1C TARGETS: 2016 ENDOCRINE SOCIETY ANNUAL
                                        CONVENTION SATELLITE SYMPOSIUM
 
The Massachusetts General Hospital     CLINICAL ENDOCRINOLOGY 2016                                        5,000
 
The Medical College of Wisconsin,      NEW TITORY FOR THE UROLOGIST: OPTIMAL MONITORING AND             150,000
 Inc. Paradigm Medical                  TREATMENT SELECTION FOR MCRPC
 Communications, LLC
 
The Medical College of Wisconsin,      OPTIMIZING STEM CELL MOBILIZATION STRATEGIES TO                  299,980
 Inc. PeerView Institute for Medical    ENHANCE SUCCESS OF AUTOLOGOUS HEMATOPOIETIC STEM CELL
 Education, Inc.                        TRANSPLANTATION
 
The Vitamin D Workshop Inc.            THE 19TH WORKSHOP ON VITAMIN D                                     5,000
 
Trustees of Boston University          PCE DIRECTED LEARNING ECOURSE: A MULTIMODAL APPROACH             152,105
 Continuing Education Alliance, LLC     TO MANAGING KNEE OSTEOARTHRITIS
 
Trustees of the University of          2016 THYROID MASTER CLASS: MANAGEMENT OF ADVANCED                 10,000
 Pennsylvania/CME                       (PROGRESSIVE MEDULLARY AND RAI-REFRACTORY
                                        DIFFERENTIATED) THYROID CANCER AND UPDATE IN THYROID/
                                        PARATHYROID ULTRASOUND IMAGING
 
University of Cincinnati PeerView      PEERVIEW INREVIEW, ``ACHIEVING RAPID CONTROL OF                   68,700
 Institute for Medical Education,       DISEASE ACTIVITY IN PATIENTS WITH MULTIPLE SCLEROSIS:
 Inc.                                   THE INCREASINGLY IMPORTANT ROLE OF DISEASEMODIFYING''
 
University of Massachusetts Medical    THE PHYSIOLOGIC BASIS FOR OPTIMIZING GLYCEMIC CONTROL            331,000
 School C-MEducation Resources, LLC     WITH BASAL INSULIN IN COMPLEX PATIENTS WITH DIABETES
 
University of Massachusetts Medical    THE FOUNDATIONAL ROLE AND PHYSIOLOGIC BASIS FOR                  305,600
 School C-MEducation Resources, LLC     OPTIMIZING GLYCEMIC CONTROL WITH LONG-ACTING
                                        INSULINS: FOCUS ON THE SAFETY-EFFICACY PROFILES OF
                                        NEW
 
University of Massachusetts Medical    NEW FRONTIERS AND CLINICAL ADVANCES IN IMMUNOTHERAPY             389,000
 School C-MEducation Resources, LLC     FOR ASTHMA: FOCUS ON BIOLOGICS-BASED MANAGEMENT OF                     Collaboration \3\
                                        MODERATE-TO-SEVERE ASTHMA IN PATIENTS
 
University of Virginia                 RENAL PHYSICIANS ASSOCIATION 2016 ANNUAL MEETING                  25,000
 
University of Virginia                 RENAL PHYSICIANS ASSOCIATION ADVANCED PRACTITIONER                 7,500
                                        CONFERENCE
 
Yale University Research To Practice   CURRENT STRATEGIES AND ONGOING RESEARCH IN THE                    80,000
                                        MANAGEMENT OF ADVANCED PROSTATE CANCER--AN
                                        INDEPENDENT SATELLITE SYMPOSIUM (ISS) HELD AS AN
 
----------------------------------------------------------------------------------------------------------------
\1\ Applicant names are provided by the requestor. If applicants apply as a group for a single educational
  activity; all applicants may be not be identified above. The Company funds other educational activities
  (including fellowships and non-physician and patient education); all of which do not appear on this report,
  but appear on other reports on this site.
\2\ ``Funding Amount'' is the amount that the Company funded during Q1, 2016 identified above based upon an
  agreement. Recipients are required to return any unused funds. Information on unused funds returned by the
  applicant on activities are not reported. ``Funding Amount'' does not include funds that may have been
  provided by other affiliated Sanofi Company Entities (e.g., Sanofi Pasteur).
\3\ Collaboration (Shared) Funding--is the full amount of a grant funded under an agreement with Regeneron, some
  or all of which may be shared between the collaborating entities.


                                      Independent Medical Education Grants
                                           1st Apr 2016-30th Jun 2016
    Sanofi US and its affiliate Genzyme Corporation are committed to supporting independent medical education
  activities in therapeutic areas in which the Company is involved, for healthcare professionals, patients, and
   consumers to improve patient care and health outcomes in therapeutic areas in which the Company is engaged.
        Sanofi US and Genzyme Corporation are part of the Sanofi Group, a global pharmaceutical company.
----------------------------------------------------------------------------------------------------------------
                                                                                                 Funding Amount
        Recipient Name(s) \1\                              Activity Title                           ($) \2\
----------------------------------------------------------------------------------------------------------------
Academic CME, LLC                      STRATEGIES FOR IMPROVING OUTCOMES IN PATIENTS WITH                20,000
                                        MULTIPLE SCLEROSIS
 
AKH Inc., Advancing Knowledge and      NOVEL MECHANISMS AND ADVANCING THERAPEUTIC PARADIGMS             350,000
 Healthcare C-MEducation Resources,     FOR OPTIMIZING REAL WORLD MANAGEMENT OF                                Collaboration \3\
 LLC                                    HYPERCHOLESTEROLEMIA: APPLYING LDLTARGETED THERAPIES
                                        FOR CV RISK REDUCTION TO THE FRONT LINES OF
                                        CARDIOVASCULAR, DIABETES, AND INTERNAL MEDICINE
                                        PRACTICE
 
AKH Inc Advancing Knowledge and        NAVIGATING THE COMPLEX MAZE OF LDL-LOWERING THERAPIES:           378,700
 Healthcare C-MEducation Resources,     A REAL WORLD ROADMAP FOR THE CARDIOVASCULAR                            Collaboration \3\
 LLC                                    SPECIALIST
 
American Academy of Physician          AAPA CONFERENCE 2016--ENDOCRINOLOGY TRACK                         12,500
 Assistants
 
American Academy of Physician          AAPA CONFERENCE 2016--NEPHROLOGY TRACK                             6,000
 Assistants
 
American Academy of Physician          AAPA CONFERENCE 2016--ORTHOPAEDICS TRACK                           7,500
 Assistants
 
American Association of Clinical       AACE 25TH ANNUAL MEETING AND CLINICAL CONGRESS--                  5,0000
 Endocrinologists                       DIABETES SESSIONS
 
American Association of Clinical       CALIFORNIA CHAPTER OF THE AMERICAN ASSOCIATION OF                 20,000
 Endocrinologists                       CLINICAL ENDOCRINOLOGISTS PRESENTS: HOT TOPICS IN
                                        DIABETES AND ENDOCRINOLOGY FOR PRIMARY CARE 2016
 
American Association of Diabetes       AADE 2016: DOES THE SHOE FIT? MATCHING THE RIGHT                 321,194
 Educators Institute for Medical and    INSULIN COMBINATION TO INDIVIDUAL PATIENTS WITH T2DM
 Nursing Education
 
American Association of Nurse          SECONDARY PREVENTION OF ASCVD: NOVEL THERAPIES TO                 75,000
 Practitioners (AANP) Medical           IMPROVE OUTCOMES IN PATIENTS WITH                                      Collaboration \3\
 Communications Media, Inc.             HYPERCHOLESTEROLEMIA
 
American College of Allergy, Asthma &  EAC 2016 - UPDATE IN ALLERGY, ASTHMA & IMMUNOLOGY                 10,000
 Immunology Eastern Allergy                                                                                    Collaboration \3\
 Conference
 
American Diabetes Association          DIABETES IS PRIMARY                                              133,595
 
American Diabetes Association          31ST ANNUAL CLINICAL CONFERENCE ON DIABETES                       32,000
 
American Society of Gene Therapy       ASGCT 19TH ANNUAL MEETING                                         26,000
 
American Society of Health-System      THE CHANGING LANDSCAPE OF HYPERCHOLESTEROLEMIA: THE              117,215
 Pharmacists                            EMERGING ROLE OF NON-STATIN THERAPIES                                  Collaboration \3\
 
American Thoracic Society              ATS 2016 INTERNATIONAL CONFERENCE--SELECTED SESSIONS              20,178
                                        IN ASTHMA                                                              Collaboration \3\
 
Baylor University Medical Center dba   UPDATE ON GLP-1 RECEPTOR AGONISTS IN THE MANAGEMENT OF            20,000
 A. Webb Roberts Center MedNet, LLC     TYPE 2 DIABETES MELLITUS
 
Carolinas Healthcare System/Charlotte  30TH ANNUAL MEETING OF THE GLOMERULAR DISEASE                      3,000
 AHEC                                   COLLABORATIVE NETWORK
 
Children's Hospital Corporation        BOSTON CHILDREN'S HOSPITAL, DIVISION OF NEPHROLOGY                 5,500
                                        WEEKLY SEMINAR SERIES
 
Consortium of Multiple Sclerosis       2016 SCIENCE OF MS MANAGEMENT                                     69,225
 Centers Nurse Practitioner
 Alternatives
 
Foundation of the Consortium of MS     2016 MS MENTORSHIP FORUM                                          25,000
 Centers
 
Horizon CME, Inc.                      GLP-1 RECEPTOR AGONISTS: AN ALTERNATIVE TO PRANDIAL              265,190
                                        INSULIN
 
Horizon CME, Inc.                      ACHIEVING LDL GOALS IN PATIENTS WITH                             187,395
                                        HYPERCHOLESTEROLEMIA: APPLYING PCSK9 INHIBITORS IN                     Collaboration \3\
                                        PRACTICE
 
Horizon CME, Inc.                      CURRENT THERAPIES FOR PROSTATE CANCER                             24,000
 
Johns Hopkins University Medical       PATIENT-CENTERED CARE IN ADVANCED PROSTATE CANCER                 60,000
 Communications Media, Inc.
 
Johns Hopkins University Medical       MULTIPLE SCLEROSIS IN THE AGE OF ENHANCED THERAPEUTIC            100,000
 Logix, LLC                             OPTIONS
 
Johns Hopkins University Medscape,     REAL-LIFE SCENARIOS: SIMULATION IN MCRPC                          50,000
 LLC
 
Medical Education Resources Tarsus     PATIENT-FOCUSED LDL-C MANAGEMENT AND RISK REDUCTION IN           200,000
 Cardio Inc. dba Cardiometabolic        CLINICAL PRACTICE: THE UTILITY OF PCSK9 INHIBITORS                     Collaboration \3\
 Health Congress
 
Med-IQ, LLC                            RECENT UPDATES IN CKD-MBD: MERGING SCIENCE AND PATIENT-           84,883
                                        CENTERED CARE
 
Med-IQ, LLC Taking Control of Your     PRACTICAL STRATEGIES FOR ADVANCING INSULIN THERAPY:            995,246.5
 Diabetes                               FROM TIMELY INITIATION AND APPROPRIATE TITRATION OF
                                        BASAL INSULIN TO ADDRESSING POST PRANDIAL GLUCOSE
                                        CONTROL
 
Medscape, LLC                          KEY CONCEPTS IN CKD-MBD: ESSENTIALS FOR IMPROVING                199,500
                                        OUTCOMES
 
Medscape, LLC                          ADVANCES IN BASAL INSULIN                                        829,075
 
Medscape, LLC                          CME-TV: INDIVIDUALIZING T2D INSULIN THERAPY UTILZIING            816,000
                                        COMPLIMENTARY MECHANISMS OF ACTION
 
Medscape, LLC                          CASE CONSIDERATIONS: HOW TO REDUCE CV RISK IN                    225,100
                                        DYSLIPIDEMIA?                                                          Collaboration \3\
 
Medscape, LLC                          2016 UPDATE: CLINICAL ADVANCEMENTS IN MODERATE TO                640,000
                                        SEVERE ATOPIC DERMATITIS                                               Collaboration \3\
 
Medscape, LLC                          WHAT DO WE KNOW ABOUT LDL-C?: A 2016 UPDATE                      242,190
                                                                                                               Collaboration\3\
 
Medscape, LLC                          A PATIENT JOURNEY THROUGH STATIN INTOLERANCE: WHAT               249,215
                                        HAVE WE LEARNED?                                                       Collaboration \3\
 
Medscape, LLC                          AN ENDOCRINOLOGY CLINIC IN DYSLIPIDEMIA: SOLVING                 237,915
                                        CHALLENGING CASES                                                      Collaboration \3\
 
Medscape, LLC                          RHEUMATOID ARTHRITIS: FOUNDATIONS IN PATHOPHYSIOLOGY,            249,825
                                        TARGETS, AND TREATMENT                                                 Collaboration \3\
 
Medscape, LLC                          WATERSHEDS IN RHEUMATOID ARTHRITIS: A CONCISE GUIDE TO            99,500
                                        MAJOR CONFERENCES IN 2016                                              Collaboration \3\
 
Michigan State Medical Society         DIABETES AND LIPID UPDATES                                         5,000
 
MidEastern Chapter of the Society of   46TH ANNUAL SPRING MEETING AND EXHIBITION OF THE                   7,500
 Nuclear Medicine                       MIDEASTERN CHAPTER OF THE SOCIETY OF NUCLEAR MEDICINE
                                        AND MOLECULAR IMAGING
 
Missouri Academy of Physician          DIABETES UPDATE FOR THE PRIMARY CARE PROVIDER                      5,000
 Assistants
 
Montefiore Medical Center PlatformQ    EVOLVING TREATMENT PARADIGMS IN METASTATIC CASTRATION-            75,000
 Health Education, LLC                  RESISTANT PROSTATE CANCER
 
National Association of Managed Care   BEST PRACTICES IN THE TREATMENT AND MANAGEMENT OF                 57,000
 Physicians, Inc.                       RELAPSING MULTIPLE SCLEROSIS
 
National Association of Managed Care   ADVANCES IN LDL-C REDUCTION: A STRATEGIC LOOK AT THE              25,000
 Physicians, Inc.                       EFFECTIVENESS OF PCSK9 INHIBITORS                                      Collaboration \3\
 
National Comprehensive Cancer          NCCN 2016 ONCOLOGY CASE MANAGER AND MEDICAL DIRECTOR              25,000
 Network, Inc.                          PROGRAM
 
National Comprehensive Cancer          2016-2017 MONTHLY ONCOLOGY TUMOR BOARDS: A                        25,000
 Network, Inc.                          MULTIDISCIPLINARY APPROACH TO INDIVIDUALIZED PATIENT
                                        CARE
 
National Jewish Health                 EVALUATION AND TREATMENT OF SEVERE ASTHMA: THE ROLE OF          94,011.5
                                        BIOLOGIC AND DIRECTED THERAPIES                                        Collaboration \3\
 
National Jewish Health Prova           ATOPIC DERMATITIS: DEFINING ITS PATHOGENESIS,                    224,850
 Education, Inc.                        TARGETING ITS TREATMENT                                                Collaboration \3\
 
National Kidney Foundation, Inc.       PATHOGENESIS AND MANAGEMENT OF FABRY DISEASE                     166,485
 
National MS Society Greater New        NEW HAMPSHIRE LIVING WELL WITH MS CONFERENCE                       1,500
 England Chapter
 
National Lipid Association             TRANSLATION OF THE LDL RECEPTOR: A NATIONAL LIPID                125,000
                                        ASSOCIATION CORE CURRICULUM INTENSIVE PROGRAM                          Collaboration \3\
 
New Jersey Academy of Family           MANAGING T2DM IN SPECIAL POPULATIONS                               6,000
 Physicians
 
North American Center for Continuing   GRAND ROUNDS IN CARDIOLOGY: PCSK9 INHIBITORS WITHIN              499,838
 Medical Education, LLC                 THE TARGETED TREATMENT APPROACH TO                                     Collaboration \3\
                                        HYPERCHOLESTEROLEMIA
 
Nurse Practitioner Alternatives        IMPROVING CARE IN MULTIPLE SCLEROSIS: A NURSING                  100,000
 International Organization of          PERSPECTIVE
 Multiple Sclerosis Nurses
 
Nurse Practitioner Alternatives        MULTIPLE SCLEROSIS 2016: WHAT NURSES NEED TO KNOW                 57,900
 International Organization of
 Multiple Sclerosis Nurses
 
Nurse Practitioner Alternatives        2016 MS COUNSELING POINTS:HIGHLIGHTING THE ROLE OF                35,625
 International Organization of          NURSES IN MULTIDISCIPLINARY MANAGEMENT OF MS
 Multiple Sclerosis Nurses
 
Oakstone Publishing, LLC PeerVoice     ADVANCEMENTS IN CARE FOR PATIENTS WITH                            29,725
 America Limited                        HYPERCHOLESTEROLEMIA AND RESIDUAL CV RISK: EMERGING                    Collaboration \3\
                                        DATA, EVOLVING STRATEGIES
 
Oregon Health & Science University     ON THE HORIZON: UPDATES IN MULTIPLE SCLEROSIS                      9,930
 Foundation
 
Penn State University i3 Health        GUIDELINE UPDATES AND EVOLVING CLINICAL PARADIGMS IN              23,500
                                        DIFFERENTIATED THYROID CANCER
 
Penn State University PeerView         PEERVIEW SELECT-A-SCENARIO LIVE: TRANSFORMING PROSTATE           120,510
 Institute for Medical Education,       CANCER CARE IN A RAPIDLY EVOLVING TREATMENT LANDSCAPE
 Inc.
 
Penn State University PeerView         PEERVIEW SELECT-A-SCENARIO LIVE: ``CRITICAL                      150,000
 Institute for Medical Education,       DISCUSSIONS IN PROSTATE CANCER: HOW TO SELECT AND
 Inc.                                   SEQUENCE THERAPIES THROUGHOUT THE DISEASE CONTINUUM''
 
Pharmacy Times Office of Continuing    ACHIEVING GLYCEMIC CONTROL: PROMOTING PATIENT SELF-               57,000
 Professional Education                 MONITORING AND EXPLORING INNOVATIVE TREATMENT
                                        STRATEGIES IN THE CONVENIENT CARE SETTING
 
Pharmacy Times Office of Continuing    MANAGING HYPERLIPIDEMIA: A NEW CHARGE FOR SPECIALTY               32,000
 Professional Education                 PHARMACY WITH THE ADVENT OF PCSK9 INHIBITORS                           Collaboration \3\
 
Pharmacy Times Office of Continuing    OPTIMIZING TREATMENT REGIMENS FOR MS: THE PHARMACIST?S            35,000
 Professional Education                 ROLE IN ADVANCING PATIENT CARE
 
Pharmacy Times Office of Continuing    MANAGING ATOPIC DERMATITIS: A PHARMACIST'S OPPORTUNITY            86,450
 Professional Education                 TO INTERVENE                                                           Collaboration \3\
 
Physicians' Education Resource, LLC    CANCER SUMMARIES AND COMMENTARIE: UPDATE FROM CHICAGO:            40,000
                                        ADVANCES IN THE TREATMENT OF GENITOURINARY CANCERS
 
Pna Centers For Neurological Research  RRNMF COURSE ON POMPE'S DISEASE RECOGNITION AND                   25,000
                                        THERAPY
 
Postgraduate Healthcare Education,     THE CHANGING LANDSCAPE IN THE TREATMENT OF RHEUMATOID             52,500
 LLC                                    ARTHRITIS: AN UPDATE FOR PHARMACISTS                                   Collaboration \3\
 
Postgraduate Institute for Medicine C- IQ&A INTERACTIVE DIABETES INTELLIGENCE ZONE: GLYCEMIC            191,000
 MEducation Resources, LLC              REGULATION THROUGH COMBINATION THERAPY--FOCUS ON
                                        SAFETY, CONVENIENCE, METABOLIC EFFECTS, HA1C CONTROL,
                                        AND EFFICACY OF COMBINATION BASAL INSULIN-GLP-1 RA
                                        REGIMENS FOR FPG AND PPG CONTROL
 
Postgraduate Institute for Medicine    WHY AREN'T THEY TAKING THEIR MEDS? PATIENT-CENTERED               33,000
 Enquiring Minds LLC                    APPROACHES TO NON-ADHERENCE IN MS
 
Primary Care Education Consortium      REMOVING THE COMPLEXITY AND CONCERNS OF INSULIN                   78,595
                                        MANAGEMENT IN TYPE 2 DIABETES, 4-HOUR WORKSHOPS TO BE
                                        HELD DURING THE METABOLIC AND ENDOCRINE DISEASE
                                        SUMMITS 2016
 
PRIME Education Inc (PRIME)            PRACTICAL SKILLS IN MEDICATION MANAGEMENT WITH NEWER             415,000
                                        CHOLESTEROL THERAPIES: CAN WE ACHIEVE PATIENT AND                      Collaboration \3\
                                        MANAGED CARE HOMEOSTASIS?
 
PRIME Education Inc (PRIME)            GME-CME ADVANCED PRACTICE SEMINAR IN MULTIPLE                    150,329
                                        SCLEROSIS: FOCUSED TRAINING FOR EFFECTIVE
                                        INDIVIDUALIZED TREATMENT DECISION-MAKING
 
PRIME Education Inc (PRIME)            RHEUMATOLOGY HOUSE CALLS--ENGAGING PATIENTS AND                  172,845
                                        PROVIDERS IN RHEUMATOID ARTHRITIS COLLABORATIVE                        Collaboration \3\
                                        LEARNING
 
PRIME Education Inc (PRIME)            NEW TARGETS IN THE THERAPEUTIC LANDSCAPE FOR ADULTS              291,095
                                        WITH ATOPIC DERMATITIS                                                 Collaboration \3\
 
Pri-Med Institute, LLC (d/b/a pmiCME)  OSTEOARTHRITIS OF THE KNEE: A MULTI-MODAL APPROACH TO            160,000
                                        PAIN MANAGEMENT
 
Pri-Med Institute, LLC (d/b/a pmiCME)  HOW LOW DO YOU GO? CLINICAL UPDATES IN LOW-DENSITY               490,479
                                        LIPOPROTEINCHOLESTEROL MANAGEMENT                                      Collaboration \3\
 
Purdue University Focus Medical        2016 ARTHROS CITY ROUNDS SERIES                                   10,000
 Communications, LLC                                                                                           Collaboration \3\
 
Research Foundation of SUNY            MEASURING QUALITY OF LIFE (QOL) IN ESRD                            5,000
 
Research To Practice                   YEAR IN REVIEW--A FOUR-PART MULTI-TUMOR REGIONAL CME              60,000
                                        SYMPOSIA SERIES FOCUSED ON THE APPLICATION OF
                                        EMERGING RESEARCH INFORMATION TO THE CARE OF PATIENTS
                                        WITH COMMON CANCERS: GENITOURINARY CANCERS MODULE
 
San Francisco Neurological Society     CALIFORNIA NEUROLOGY SOCIETY - UPDATES IN NEUROLOGY                3,000
 Association of California              2016
 Neurologists Foundation
 
Scripps Health                         ANNUAL NEW APPROACHES TO OPTIMIZE REAL-WORLD DIABETES             50,000
                                        CARE: SPRING CONFERENCE
 
Society for Urologic Nurses and        COMPETENCE IN ADVANCED PROSTATE CANCER REGIONAL ONS               30,000
 Associates (SUNA)                      CHAPTER NURSING FORUMS. DEVELOPING STRATEGIES FOR
                                        SEQUENCING AND COMBINING THERAPIES: NURSING
                                        CONSIDERATIONS FOR IMPLEMENTING A TAILORED TREATMENT
                                        APPROACH
 
Society of Nuclear Medicine            61ST ANNUAL MEETING OF THE SOUTHWESTERN CHAPTER, SNMMI             2,000
 Southwestern Chapter of the Society
 of Nuclear Medicine
 
Swedish Medical Center Foundation      SIXTH ANNUAL INTENSIVE UPDATE IN NEUROLOGY                         3,000
 
Texas A&M University System Health     12TH ANNUAL DIABETES CONFERENCE: 'DIABETES HEAD TO                10,000
 Science Center Coastal Be              TOE'
 
The Endocrine Society                  ENDO 2016 GENYZME THYROID SESSIONS                               100,000
 
The Omnia-Prova Education              MANAGEMENT OF RA: GLOBAL OUTLOOK AND LATIN AMERICAN              311,067
 Collaborative, Inc. Prova Education,   IMPLICATIONS                                                           Collaboration \3\
 Inc.
 
Trustees of Boston University          KEYS TO ACHIEVING OPTIMAL GLUCOSE CONTROL: EARLY                 375,000
 Continuing Education Alliance, LLC     INSULIN INITIATION AND CONTROL OF POSTPRANDIAL
                                        GLUCOSE
 
Trustees of Boston University          IMPLEMENTING NEW THERAPIES FOR REFRACTORY                        350,000
 Continuing Education Alliance, LLC     DYSLIPIDEMIA: PRACTICAL CONSIDERATIONS FOR CLINICAL                    Collaboration \3\
                                        PRACTICE
 
Ultimate Medical Academy, LLC dba      IMPROVING OUTCOMES IN SEVERE ASTHMA: A NEW ERA IN                185,333
 Global Education Group Integritas      PRECISION MEDICINE                                                     Collaboration \3\
 Communications, LLC
 
UMA MLG, LLC                           COMPREHENSIVE DYSLIPIDEMIA MANAGEMENT: A VIRTUAL                 249,825
                                        REALITY TOUR BEYOND STATIN MONOTHERAPY                                 Collaboration\3\
 
University of Chicago Intelligent      INSIDE DYSLIPIDEMIA MANAGEMENT: IMPROVING RISK                   285,734
 Medical Decisions, Inc.                ASSESSMENT, REFERRALS AND LIPID GOAL ATTAINMENT FOR                    Collaboration \3\
                                        HIGH-RISK CV PATIENTS INSPIRING SYSTEM IMPROVEMENT
                                        WITH DATA-DRIVEN EDUCATION
 
University of Cincinnati Advances in   MAUIDERM NP+PA SUMMER 2016                                        25,000
 Cosmetic and Medical Dermatology                                                                              Collaboration \3\
 
University of Kansas Endowment         NEUROMUSCULAR REVIEW COURSE SERIES 2016                           15,000
 Association
 
University of Massachusetts Medical    PIVOTAL TREATMENT ADVANCES IN BIOLOGIC THERAPY FOR               376,000
 School C-MEducation Resources, LLC     ATOPIC DERMATITIS (AD): FOCUS ON THE                                   Collaboration \3\
                                        IMMUNOPATHOBIOLOGY OF AD AND ROLE OF EVOLVING
                                        BIOLOGIC THERAPIES FOR OPTIMIZING OUTCOMES IN
                                        PATIENTS WITH MODERATE-TO-SEVERE AND TREATMENT-
                                        RESISTANT AD
 
University of Rochester Society of     2016 SOCIETY FOR INVESTIGATIVE DERMATOLOGY ANNUAL                 50,000
 Investigative Dermatology              MEETING                                                                Collaboration \3\
 
University of Southern California      VAN DER MEULEN SYMPOSIUM: MULTIPLE SCLEROSIS UPDATE               20,000
 
University of Tennessee Advanced       ONCOLOGY PHARMACY CONSULTS: UPDATES ON THE MANAGEMENT             45,000
 Studies in Medicine                    OF PROSTATE CANCER
 
University of Texas Health Science     AMERICAN SOCIETY OF CLINICAL ONCOLOGY (ASCO) 2016                  3,500
 Center at San Antonio                  REVIEW
 
University of Vermont and State        NEW ENGLAND THYROID CONFERENCE                                    10,000
 Agricultural College
 
USF Health Professions Conferencing    13TH ANNUAL ROCKY MOUNTAIN METABOLIC SYNDROME                      5,000
 Corporation CEConsultants, LLC         SYMPOSIUM
 
Wellmont Health System                 14TH ANNUAL DIABETES SYMPOSIUM                                     4,000
 
Yale University                        INAUGURAL 1-95 INFILTRATIVE CARDIOMYOPATHY CONFERENCE              5,000
----------------------------------------------------------------------------------------------------------------
\1\ Applicant names are provided by the requestor. If applicants apply as a group for a single educational
  activity; all applicants may be not be identified above. The Company funds other educational activities
  (including fellowships and non-physician and patient education); all of which do not appear on this report,
  but appear on other reports on this site.
\2\ ``Funding Amount'' is the amount that the Company funded during Q2, 2016 identified above based upon an
  agreement. Recipients are required to return any unused funds. Information on unused funds returned by the
  applicant on activities are not reported. ``Funding Amount'' does not include funds that may have been
  provided by other affiliated Sanofi Company Entities (e.g., Sanofi Pasteur).
\3\ Collaboration (Shared) Funding--is the full amount of a grant funded under an agreement with Regeneron, some
  or all of which may be shared between the collaborating entities.


                                      Independent Medical Education Grants
                                           1st July 2016-30th Sep 2016
    Sanofi US and its affiliate Genzyme Corporation are committed to supporting independent medical education
  activities in therapeutic areas in which the Company is involved, for healthcare professionals, patients, and
   consumers to improve patient care and health outcomes in therapeutic areas in which the Company is engaged.
        Sanofi US and Genzyme Corporation are part of the Sanofi Group, a global pharmaceutical company.
----------------------------------------------------------------------------------------------------------------
                                                                                                 Funding Amount
        Recipient Name(s) \1\                              Activity Title                           ($) \2\
----------------------------------------------------------------------------------------------------------------
American Association of Clinical       ORR-AACE 18TH ANNUAL MEETING                                       5,000
 Endocrinologists
 
American Association of Clinical       MID ATLANTIC-AACE 14TH ANNUAL MEETING                              2,500
 Endocrinologists
 
American Association of Clinical       TEXAS-AACE ANNUAL MEETING & TEXAS ENDOCRINE SURGICAL               5,000
 Endocrinologists                       SYMPOSIUM
 
American Association of Clinical       NEVADA AACE ENDOCRINOLOGY FOR THE NON ENDOCRINOLOGISTS             5,000
 Endocrinologists                       AND ANNUAL MEETING
 
American Association of Clinical       NEVADA-AACE ENDOCRINOLOGY FOR THE NON ENDOCRINOLOGISTS             7,500
 Endocrinologists                       AND ANNUAL MEETING
 
American Association of Nurse          BEST PRACTICES IN ACHIEVING OPTIMAL A1C TARGETS AND              141,980
 Practitioners (AANP)                   POST PRANDIAL GLYCEMIC CONTROL
 
American Diabetes Association          14TH ANNUAL PROFESSIONAL EDUCATION SYMPOSIUM, AN                  10,000
                                        AFTERNOON WITH DIABETES EXPERTS: DIABETES DISTRESS,
                                        PHYSICAL ACTIVITY, MEDICATIONS, AND UPDATES TO THE
                                        STANDARDS
 
American Health Resources, Inc.        EXAMINING NEW OPTIONS IN THE MANAGEMENT OF INSULIN                 4,600
                                        RESISTANT TYPE 2 DIABETES: A FOCUS ON BASAL INSULIN
                                        THERAPY
 
American Society for Blood and Marrow  2017 ASBMT/SANOFI NEW INVESTIGATOR AWARD                          65,000
 Transplantation
 
Antidote Education Company             MANAGING DIABETES IN OLDER POPULATIONS                            50,000
 
California Academy of Physician        MANAGEMENT OF OSTEOARTHRITIS IN THE PRIMARY SETTING                4,000
 Assistants
 
California Academy of Physician        2016 ANNUAL MEETING OF THE CALIFORNIA ACADEMY OF                   4,000
 Assistants                             PHYSICIAN ASSISTANTS (CAPA): UPDATES IN TYPE 2
                                        DIABETES CARE
 
Cardiovascular Research Foundation     BEST MANAGEMENT FOR COMPLEX PATIENTS WITH COMPLEX                 58,100
                                        DISEASE: THE NEXT FRONTIER BEYOND REVASCULARIZATION
 
Consortium of Multiple Sclerosis       2016 CMSC ANNUAL MEETING SCIENTIFIC PROGRAM                       25,000
 Centers Nurse Practitioner
 Alternatives
 
Consortium of Multiple Sclerosis       MS AT THE CUTTING EDGE: A 5-PART WEBINAR SERIES                   56,700
 Centers Nurse Practitioner
 Alternatives
 
Dignity Health MandatoryCE LLC         5TH ANNUAL ARIZONA DIABETES SYMPOSIUM                             50,000
 
Dignity Health MandatoryCE LLC         2016 ARKANSAS DIABETES SYMPOSIUM: FOCUS ON PREVENTION,            35,000
                                        CURRENT TREATMENTS, AND COMORBIDITIES
 
Elsevier Office of Continuing Medical  ECTRIMS 2016: OPTIMALLY MANAGING PATIENTS WITH                    85,000
 Education Academic CME, LLC            MULTIPLE SCLEROSIS THROUGH INDIVIDUALIZED TREATMENT
                                        OPTIONS
 
Emory University                       9TH WORLD CONGRESS ON PREVENTION OF DIABETES AND ITS              50,000
                                        COMPLICATIONS
 
Florida Academy of Physician           EVALUATING KIDNEY DISEASE: KIDNEY KASES                            5,000
 Assistants
 
Florida Academy of Physician           JOINT INJECTIONS                                                   5,500
 Assistants
 
Foundation for Orthopaedic Research    ORTHOPAEDICS FOR THE PRIMARY CARE PRACTITIONER &                   5,000
 and Education, Inc.                    REHABILITATION THERAPIST
 
Horizon CME, Inc.                      GLP-1 RECEPTOR AGONIST AND BASAL INSULIN: AN EMERGING             53,253
                                        STANDARD FOR TYPE DIABETES TREATMENT
 
Horizon CME, Inc.                      ULTRALONG-ACTING BASAL INSULINS: WHERE DO THEY FIT?               53,253
 
Integritas Communications, LLC         CLINICAL UPDATES IN THE MANAGEMENT OF SEVERE ASTHMA:               5,000
 Ultimate Medical Academy, LLC dba      NEW STRATEGIES TO INDIVIDUALIZE LONG-TERM CARE                         Collaboration \3\
 Global Education Group
 
LeBonheur Children's Hospital          BACK TO SCHOOL DIABETES CONFERENCE                                 3,828
 
Medical Education Resources Tarsus     COMBINING GLP-1RAS WITH INSULIN TO IMPROVE GLUCOSE               159,650
 Cardio Inc. dba Cardiometabolic        CONTROL
 Health Congress
 
Medical Learning Institute, Inc.       PEERVIEW VIDEO INSESSION AT AAN 2016, ``STAYING                  131,530
 PeerView Institute for Medical         CURRENT WITH THE LATEST UPDATES ON APPROVED DISEASE-
 Education, Inc.                        MODIFYING THERAPIES FOR MULTIPLE SCLEROSIS
                                        MANAGEMENT: CLINICAL HIGHLIGHTS FROM VANCOUVER''
 
Med-IQ, LLC                            SEQUENCING TREATMENT FOR METASTATIC CASTRATION-                  158,565
                                        RESISTANT PROSTATE CANCER: HOW TO MATCH PATIENTS TO
                                        THE RIGHT THERAPY
 
Med-IQ, LLC                            THE EVOLVING THERAPEUTIC LANDSCAPE FOR MODERATE-TO-               88,759
                                        SEVERE ATOPIC DERMATITIS                                               Collaboration \3\
 
National Association for Continuing    POSTPRANDIAL HYPERGLYCEMIA AND GLP-1 RECEPTOR                    150,000
 Education                              AGONISTS: EFFECTIVE STRATEGIES TO ACHIEVE GOALS
 
National Association of Managed Care   NEW PERSPECTIVES AND EMERGING TREATMENT PARADIGMS IN              57,000
 Physicians, Inc.                       THE MANAGEMENT OF RELAPSING MULTIPLE SCLEROSIS
 
National Association of Managed Care   CLINICAL ADVANCES IN ATOPIC DERMATITIS: NOVEL                     57,000
 Physicians, Inc.                       THERAPIES FOR IMPROVED PATIENT OUTCOMES
 
National Association of Managed Care   IMPROVING PATIENT OUTCOMES WITH INDIVIDUALIZED THERAPY            57,000
 Physicians, Inc.                       IN THE MANAGEMENT OF TYPE 2 DIABETES
 
National Kidney Foundation, Inc.       25TH ANNUAL FELLOWS RESEARCH FORUM                                 3,500
 
National Kidney Foundation, Inc.       CHRONIC KIDNEY DISEASE-MINERAL BONE DISORDER:                    149,420
 University of Illinois at Chicago      IMPLICATIONS FOR CARDIAC OUTCOMES
 
National Medical Association           STRATEGIES TO ACHIEVE BETTER CLINICAL OUTCOMES IN TYPE           200,000
                                        2 DIABETES AND ITS THERAPEUTIC COMPLICATIONS
 
Penn State University Antidote         16TH ANNUAL DIABETES SYMPOSIUM                                    15,000
 Education Company
 
Penn State University Medical          STRATEGIES FOR IMPROVING OUTCOMES IN PATIENTS WITH MS             15,000
 Communications Media, Inc.
 
Pennsylvania Society of Physician      NEW TREATMENT OPTIONS IN DIABETES MELLITUS                         8,000
 Assistants
 
Potomac Center for Medical Education   EXPANDING DMD TREATMENT OPTIONS FOR PATIENTS WITH MS             205,000
 Rockpointe Corporation
 
Primary Care Network, Inc. PlatformQ   THE EVOLUTION OF BASAL INSULINS: ONE SMALL STEP OR A             100,000
 Health Education, LLC                  GIANT LEAP?
 
Projects In Knowledge MedPage Today,   NEUROLOGY MASTERY IN MULTIPLE SCLEROSIS                          120,000
 LLC
 
Regents of the University of           6TH ANNUAL UC IRVINE HEALTH NEUROMUSCULAR COLLOQUIUM              20,000
 California
 
Regents of the University of Colorado  PRACTICAL WAYS TO ACHIEVE TARGETS IN DIABETES CARE               200,000
 
Regents, University of California      THE 4TH ANNUAL UCLA DIABETES SYMPOSIUM                            10,000
 
Scripps Health                         ANNUAL NEW APPROACHES TO OPTIMIZE REAL-WORLD DIABETES             70,000
                                        CARE: FALL CONFERENCE AND ENDURING MATERIALS
 
The Board of Trustees of the UA for    SPECIAL NEPHROLOGY RESEARCH AND TRAINING CENTER                   15,000
 the UA at Birmingham                   SYMPOSIUM--11/9/15
 
The Medical College of Wisconsin,      2016 ASBMT CLINICAL RESEARCH TRAINING COURSE                      25,000
 Inc. American Society for Blood and
 Marrow Transplantation
 
University of California, San Diego--  PROMOTING BEHAVIOR CHANGE IN DIABETES: A SKILL                    50,000
 Behavioral Diabetes Institute          BUILDING PROGRAM FOR HEALTH CARE PROFESSIONALS
 
University of California, San Diego    ADDRESSING THE NATURAL HISTORY OF TYPE 2 DIABETES:               142,899
 Taking Control of Your Diabetes        PRACTICAL APPROACHES TO CONTROLLING FASTING AND POST-
                                        PRANDIAL GLUCOSE LEVELS
 
University of Cincinnati Global        HE METABOLIC & ENDOCRINE DISEASE SUMMIT (MEDS) 2016               25,000
 Academy for Medical Education, LLC T
 
----------------------------------------------------------------------------------------------------------------
\1\ Applicant names are provided by the requestor. If applicants apply as a group for a single educational
  activity; all applicants may be not be identified above. The Company funds other educational activities
  (including fellowships and non-physician and patient education); all of which do not appear on this report,
  but appear on other reports on this site.
\2\ ``Funding Amount'' is the amount that the Company funded during Q3, 2016 identified above based upon an
  agreement. Recipients are required to return any unused funds. Information on unused funds returned by the
  applicant on activities are not reported. ``Funding Amount'' does not include funds that may have been
  provided by other affiliated Sanofi Company Entities (e.g., Sanofi Pasteur).
\3\ Collaboration (Shared) Funding--is the full amount of a grant funded under an agreement with Regeneron, some
  or all of which may be shared between the collaborating entities.


                                      Independent Medical Education Grants
                                           1st Oct 2016-31th Dec 2016
    Sanofi US and its affiliate Genzyme Corporation are committed to supporting independent medical education
  activities in therapeutic areas in which the Company is involved, for healthcare professionals, patients, and
   consumers to improve patient care and health outcomes in therapeutic areas in which the Company is engaged.
        Sanofi US and Genzyme Corporation are part of the Sanofi Group, a global pharmaceutical company.
----------------------------------------------------------------------------------------------------------------
                                                                                                 Funding Amount
        Recipient Name(s) \1\                              Activity Title                           ($) \2\
----------------------------------------------------------------------------------------------------------------
American Academy of Pas                2016 ADULT HOSPITAL MEDICINE BOOT CAMP                             5,000
 
American Association of Clinical       CALIFORNIA CHAPTER OF THE AMERICAN ASSOCIATION OF                  5,000
 Endocrinologists                       CLINICAL ENDOCRINOLOGISTS (CA AACE) 16TH ANNUAL
                                        MEETING & SYMPOSIUM
 
American Association of Clinical       DIABETES DAY FOR PRIMARY CARE CLINICIANS ADVANCES IN              75,000
 Endocrinologists                       DIABETES CARE
 
American College of Allergy, Asthma &  PLENARY SESSION: MODERN THERAPIES FOR ALLERGIC SKIN               35,000
 Immunology                             DISEASES                                                               Collaboration \3\
 
American Health Resources, Inc.        NEW COMPLEMENTARY COMBINATION THERAPY FOR DIABETES:               21,800
                                        FIXED DOSE BASAL INSULINS AND GLP-1 RECEPTOR AGONISTS
 
American Nephrology Nurses'            IMPROVING PATIENT OUTCOMES IN CKD-MBD: INDIVIDUALIZED            139,250
 Association                            MANAGEMENT AND ENHANCED PATIENT ENGAGEMENT
 
American Society of Nephrology         CKD-MBD GUIDELINES: A CRITICAL APPRAISAL OF RECENT               181,790
                                        STUDIES
 
American Society of Transplantation    AST FELLOWS SYMPOSIUM ON TRANSPLANTATION (2016)                   35,000
 
American Thyroid Association, Inc.     3RD ANNUAL E. CHESTER RIDGWAY TRAINEE CONFERENCE                  25,000
 University of Colorado School of
 Medicine
 
American Thyroid Association, Inc.     86TH ANNUAL MEETING OF THE AMERICAN THYROID                       50,000
 University of Colorado School of       ASSOCIATION
 Medicine
 
American Urological Association        ADVANCEMENTS IN UROLOGY 2017, AN AUA/JUA SYMPOSIUM                15,000
 
American Urological Association        ADVANCED PROSTATE CANCER: MANAGING THE SPECTRUM OF THE            60,000
 Education & Research, Inc.             DISEASE
 
Annenberg Center for Health Sciences   EXPERTPERSPECTIVES: SHIFTING PARADIGMS, EMERGING                 224,355
 at Eisenhower                          TREATMENTS IN MODERATE TO SEVERE ATOPIC DERMATITIS                     Collaboration \3\
 
Annenberg Center for Health Sciences   DEVELOPMENT OF SPANISH LANGUAGE VERSION OF: ANIMATED              75,000
 at Eisenhower Postgraduate Institute   MULTIPLE SCLEROSIS (MS) PATIENT AN ANIMATED PATIENTS
 for Medicine Prime Medic               GUIDE TO MS/ANIMADAS DE ESCLEROSIS MULTIPLE (EM)
                                        PACIENTE GUIA DEL PACIENTES ANIMADA A EM
 
Augusta University                     NEUROLOGY FOR THE NON-NEUROLOGIST                                  5,000
 
AXIS Medical Education, Inc.           AUTOLOGOUS HEMATOPOIETIC STEM CELL TRANSPLANTATION AND            74,580
                                        MOBILIZATION IN MULTIPLE MYELOMA: CURRENT DEBATE AND
                                        DEVELOPMENTS
 
Baylor Scott & White Health Baylor     3RD ANNUAL SYMPOSIUM ON INDIVIDUALIZED NOVEL DISEASE-             40,000
 University Medical Center dba A.       MODIFYING TREATMENT OPTIONS FOR MULTIPLE SCLEROSIS
 Webb Roberts Center MedNet, LLC
 
Baylor Scott & White Health MedNet     EMERGING BIOLOGICAL THERAPIES FOR ATOPIC DERMATITIS IN            35,000
                                        CHILDREN AND ADULTS                                                    Collaboration \3\
 
California Optometric Association      FABRY DISEASE--OPHTHALMIC MANIFESTATIONS AND RECENT                9,650
                                        ADVANCES
 
Cleveland Clinic Educational           MULTIPLE SCLEROSIS CASE-BASED ONLINE MONOGRAPH                    25,000
 Foundation
 
Clinical Care Options, LLC             NEW DIRECTIONS IN GU CANCERS: HIGHLIGHTS FROM THE 2017            25,000
 Postgraduate Institute for Medicine    GENITOURINARY CANCERS SYMPOSIUM
 
C-MEducation Resources, LLC AKH Inc    NEW FRONTIERS AND PIVOTAL CLINICAL ADVANCES IN                   297,000
 Advancing Knowledge and Healthcare     PATHOIMMUNOBIOLOGY OF ATOPIC DERMATITIS: THE                           Collaboration \3\
                                        TRANSLATIONAL PATH IN ATOPIC DERMATITIS AND
                                        IMPLICATIONS FOR DERMATOLOGY PRACTICE
 
Consortium of Multiple Sclerosis       ADDRESSING COMORBIDITIES IN THE DIAGNOSIS AND                     85,000
 Centers Nurse Practitioner             MANAGEMENT OF PATIENTS WITH MULTIPLE SCLEROSIS: A
 Alternatives                           RESOURCE GUIDE FOR CLINICIANS
 
Consortium of Multiple Sclerosis       CLINICAL CONSULT: CASES AND COMPREHENSIVE CARE IN MS             115,200
 Centers Nurse Practitioner
 Alternatives
 
Consortium of Multiple Sclerosis       MONITORING AND FOLLOW-UP IN MULTIPLE SCLEROSIS                    60,725
 Centers Nurse Practitioner             COMPREHENSIVE CARE
 Alternatives
 
Continuing Education Alliance, LLC     TARGETED THERAPIES IN MODERATE TO SEVERE ATOPIC                   92,550
 Board of Regents for University of     DERMATITIS: EMERGING OPTIONS                                           Collaboration \3\
 Nebraska
 
Creative Educational Concepts, Inc.    ADVANCED PROSTATE CANCER: SEARCHING FOR OPTIMAL                   15,000
                                        THERAPY SEQUENCE AND ASSESSING EMERGING TREATMENT
                                        OPTIONS
 
Delaware Academy of Physician          MULTIPLE SCLEROSIS                                                 2,200
 Assistants Inc.
 
Elsevier Office of Continuing Medical  CLINICAL ADVANCES IN RHEUMATOID ARTHRITIS: A FOCUS ON            350,000
 Education Advanced Studies in          IMPROVING PATIENT OUTCOMES
 Medicine
 
Elsevier Office of Continuing Medical  SPOTLIGHT ON FABRY DISEASE: DIAGNOSIS, GENOTYPE-                 200,000
 Education Excerpta Medica              PHENOTYPE CORRELATION, AND MULTIDISCIPLINARY PATIENT
                                        CARE
 
Elsevier Office of Continuing Medical  ESMO2016: A THERAPEUTIC UPDATE ON THE MANAGEMENT OF               90,000
 Education Excerpta Medica BV           PATIENTS WITH PROSTATE CANCER
 
Excel Continuing Education             MULTIPLE SCLEROSIS: MANAGING THE DISEASE, ITS SYMPTOMS             7,000
                                        AND QUALITY OF LIFE (PART OF THE SOUTH FLORIDA
                                        NEUROLOGY SYMPOSIUM: IMPROVING PATIENT OUTCOMES)
 
Excel Continuing Education             NEW DIRECTIONS IN THE MANAGEMENT OF POMPE DISEASE                 64,120
 
Florida Academy of Physician           MULTIPLE SCLEROSIS                                                 5,000
 Assistants Inc.
 
Foundation of the Consortium of MS     2016-2017 ROBERT LISAK, MD MEDICAL STUDENT RESEARCH                8,000
 Centers                                SCHOLARSHIP
 
Global Academy for Medical Education   SKIN DISEASE EDUCATION FOUNDATION'S 17TH ANNUAL LAS               25,000
 Postgraduate Institute for Medicine    VEGAS DERMATOLOGY SEMINAR FEATURING THE 13TH ANNUAL                    Collaboration \3\
 Rutgers, the State University          PSORIASIS FORUM
 
Global Academy for Medical Education   16TH ANNUAL CARIBBEAN DERMATOLOGY SYMPOSIUM                       20,000
 Rutgers Biomedical and Health                                                                                 Collaboration \3\
 Sciences
 
Global Academy for Medical Education   SKIN DISEASE EDUCATION FOUNDATION'S 41ST ANNUAL HAWAII            50,000
 University of Louisville Research      DERMATOLOGY SEMINAR                                                    Collaboration \3\
 Foundation
 
Haymarket Medical Education            BASAL INSULIN PLUS GLP-1 RAS: THERAPEUTIC SYNERGIES TO           146,788
                                        OPTIMIZE PATIENT OUTCOMES: 4 VIDEO ``HOUSE CALLS''
                                        DISCUSSIONS AMONG EXPERTS
 
Illinois Academy of Physician          JOINT INJECTABLES                                                  4,000
 Assistants
 
Illinois Academy of Physician          CHRONIC KIDNEY DISEASE                                             5,000
 Assistants
 
Indiana Academy of Physician           ``WHAT IS CHRONIC KIDNEY DISEASE (CKD) AND END STAGE               6,500
 Assistants                             RENAL DISEASE (ESRD)?''
 
Indiana Neurological Society Indiana   DEMYELINATING DISEASES: WHAT TO DO WHEN THE INSULATION             5,000
 State Medical Association              BEGINS TO FRAY
 
Integritas Communications Global       LOOKING BENEATH THE SURFACE IN ATOPIC DERMATITIS:                361,807
 Education Group                        TARGETING IMMUNE DYSREGULATION AND DELIVERING                          Collaboration \3\
                                        COMPREHENSIVE CARE
 
Integritas Communications, LLC UMA      ATOPIC DERMATITIS: NEW PERSPECTIVES ON MANAGING A               267,480
 Education, Inc. dba Global Education   CHRONIC INFLAMMATORY DISEASE                                           Collaboration \3\
 Group
 
Integritas Communications, LLC UMA     CLINICAL ADVANCES IN ATOPIC DERMATITIS: EXPERT                   202,218
 Education, Inc. dba Global Education   INSIGHTS INTO NEW AND EMERGING THERAPIES                               Collaboration \3\
 Group
 
Integritas Communications, LLC UMA     CLINICAL UPDATES IN RHEUMATOID ARTHRITIS: NEW                    249,900
 Education, Inc. dba Global Education   STRATEGIES TO TARGET REMISSION AND INDIVIDUALIZE                       Collaboration \3\
 Group                                  COMPREHENSIVE CARE
 
International Eczema Council           PSORIASIS AND ATOPIC DERMATITIS: TWO DISEASES OR ONE             100,000
 International Psoriasis Council        SPECTRUM?                                                              Collaboration \3\
 
International Organization of MS       NP CONNECTIONS: THE ROLE OF THE NURSE PRACTITIONER IN             75,000
 Nurses Nurse Practitioner              MULTIPLE SCLEROSIS CARE
 Alternatives
 
Kentucky Academy of Physician          JOINT INJECTION WORKSHOP                                           5,000
 Assistants
 
Medical Learning Institute Inc. PVI    PEERVIEW LIVE AT CMSC 2017, GUIDING PATIENTS THROUGH             345,810
 Peerview Institute for Medical         THE RISKS AND BENEFITS OF DISEASE-MODIFYING THERAPY:
 Education Inc.                         PATIENT STORIES OF SHARED DECISION-MAKING THROUGHOUT
                                        THE COURSE OF MULTIPLE SCLEROSIS
 
Medical Learning Institute Inc. PVI     PEERVIEW LIVE AT ACMG 2017 STRENGTHENING THE GENETICS-          219,430
 Peerview Institute for Medical         HEMATOLOGY PARTNERSHIP TO SHORTEN THE PATH TO
 Education Inc.                         DIAGNOSIS & TREATMENT OF GAUCHER DISEASE TYPE 1: A
                                        PATIENT STORY
 
Medical Learning Institute Inc. PVI,   PEERVIEW VIDEO INPLAY NOVEL OPTIONS AND PATIENT                  169,480
 PeerView for Medical Education Inc.    PERSPECTIVES IN RHEUMATOID ARTHRITIS: INDIVIDUALIZING                  Collaboration \3\
                                        CARE FOR THERAPEUTIC SUCCESS
 
Medical Learning Institute Inc. PVI,   PEERVIEW VIDEO INREVIEW: ASSESSING THE COMPARATIVE                60,000
 PeerView Institute for Medical         EFFECTIVENESS OF DISEASE-MODIFYING THERAPIES: WHAT
 Education                              CAN BE LEARNED FROM HEAD-TO-HEAD CLINICAL TRIALS AND
                                        RECENT NUMBER-NEEDED-TO-TREAT ANALYSES?
 
Medical Learning Institute, Inc.       PEERVIEW IN REVIEW, ``DELAYING DISABILITY PROGRESSION            106,800
 PeerView Institute for Medical         IN THE MULTIPLE SCLEROSIS PATIENT: WHAT CAN WE LEARN
 Education, Inc.                        FROM AVAILABLE DATA ON APPROVED DISEASE-MODIFYING
                                        THERAPY?''
 
Medical Learning Institute, Inc.       PEERVIEW TALKS: HIGHLY EFFECTIVE DISEASE-MODIFYING                65,000
 PeerView Institute for Medical         THERAPIES FOR MULTIPLE SCLEROSIS: WHEN AND IN WHOM
 Education, Inc.                        SHOULD THEY BE USED?
 
Medical Learning Institute, Inc.       NEW DEVELOPMENTS IN THE TREATMENT OF ATOPIC                      156,480
 PeerView Institute for Medical         DERMATITIS: CLINICAL HIGHLIGHTS FROM VIENNA                            Collaboration \3\
 Education, Inc.
 
Med-IQ, LLC                            DIFFERENTIATING GAUCHER DISEASE FROM OTHER HEMATOLOGIC           290,043
                                        CONDITIONS: EVERY DAY COUNTS
 
Med-IQ, LLC                            LYSOSOMAL STORAGE DISEASES: NEWBORN SCREENING UPDATES            261,483
                                        AND IMPLICATIONS FOR LONG-TERM CARE
 
Med-IQ, LLC                            FABRY DISEASE : WHEN TO TREAT                                    100,000
 
Michigan State Medical Society         CARING FOR PATIENTS WITH A FOCUS ON THE KIDNEYS                    5,000
 
MS Views And News Inc.                 2016 NEUROLOGICAL ASPECTS OF MS AND BEYOND--SYMPOSIUM             17,500
 
MSWorld Inc.                           2016 MSWORLD-HOSTED TALKS SERIES                                  35,000
 
National Association of Managed Care   NEW HORIZONS IN THE TREATMENT AND MANAGEMENT OF                   70,000
 Physicians, Inc.                       MULTIPLE SCLEROSIS: BEST PRACTICES FOR IMPROVED
                                        PATIENT OUTCOMES
 
National Association of Managed Care   NEW HORIZONS IN THE TREATMENT AND MANAGEMENT OF ATOPIC            90,000
 Physicians, Inc.                       DERMATITIS (AD): HOW NOVEL THERAPIES ARE CHANGING THE                  Collaboration \3\
                                        TREATMENT PARADIGM
 
National Jewish Health                 THE 39TH ANNUAL NATIONAL JEWISH HEALTH PULMONARY &                20,000
                                        ALLERGY UPDATE                                                         Collaboration \3\
 
National Kidney Foundation             12TH ANNUAL JOINT MEETING OF THE UPSTATE AND WESTERN               7,500
                                        NEW YORK COUNCILS ON RENAL NUTRITION
 
National Kidney Foundation             STRATEGIES TO IMPROVE PATIENT OUTCOMES IN CKD-MBD                243,260
                                        MANAGEMENT
 
Neurologic Disease Foundation          21ST FALL MS SEMINAR--OPTIMIZING MANAGEMENT OF MS                  5,995
 
New England Section American           85TH ANNUAL MEETING NEW ENGLAND SECTION OF THE                    10,000
 Urological Assn American Urological    AMERICAN UROLOGICAL ASSOCIATION
 Association Education and Research,
 Inc.
 
Not-For-Profit Hospital Corporation    THYROID CANCER MANAGEMENT? AN OVERVIEW AND UPDATE OF               2,750
                                        NEW TREATMENT OPTIONS
 
Not-For-Profit Hospital Corporation    END STAGE RENAL DISEASE FOR THE NON-NEPHROLOGIST                   1,910
 
PeerVoice America Limited Oakstone     EMERGING PARADIGMS IN ATOPIC DERMATITIS: TARGETING THE           492,850
 Publishing, LLC.                       UNDERLYING PATHOLOGY                                                   Collaboration \3\
 
Penn State College of Medicine         CASES FROM THE COMMUNITY: CLINICAL INVESTIGATORS                  80,000
 Research To Practice                   PROVIDE THEIR PERSPECTIVES ON EMERGING RESEARCH AND
                                        ACTUAL PATIENTS WITH ADVANCED PROSTATE CANCER]AN
                                        INDEPENDENT SATELLITE SYMPOSIUM (ISS) HELD AS A
                                        PREMIUM ANCILLARY EVENT DURING THE 2017 GENITOURINARY
                                        CANCERS SYMPOSIUM
 
Penn State University                  PENN STATE HERSHEY CANCER INSTITUTE: CONTEMPORARY                  3,500
                                        TOPICS IN THYROID CANCER
 
Pennsylvania Society of Physician      MULTIPLE SCLEROSIS: A PRIMARY CARE PERSPECTIVE                     4,500
 Assistants
 
Pharmacy Times Continuing Education    AN AMERICAN JOURNAL OF MANAGED CARE SYMPOSIUM:                    92,358
                                        APPLYING MANAGED CARE STRATEGIES TO THE ADVANCING
                                        LANDSCAPE OF MULTIPLE SCLEROSIS
 
Pharmacy Times Office of Continuing    MANAGING ATOPIC DERMATITIS: A PHARMACIST'S OPPORTUNITY            23,200
 Professional Education                 TO INTERVENE                                                           Collaboration \3\
 
Postgraduate Institute for Medicine    BEST PRACTICES FOR MANAGING ADVERSE EVENTS ASSOCIATED             40,000
 Clinical Care Options, LLC             WITH NOVEL THERAPIES FOR PATIENTS WITH HEMATOLOGIC
                                        MALIGNANCIES
 
Potomac Center for Medical Education   NOVEL INSIGHTS IN ATOPIC DERMATITIS: PATHWAYS,                   469,900
 Rockpointe Corporation                 BIOMARKERS, AND PHENOTYPES FOR A TARGETED APPROACH
 
President and Fellows of Harvard       DIABETES AND CARDIOMETABOLIC SYNDROME IN PRIMARY CARE             10,000
 College Beth Israel Deaconess
 Department of Medicine
 
President and Fellows of Harvard       18TH BIENNIAL HARVARD UROLOGIC CANCER COURSE                      50,000
 College Dana Farber Cancer Institute
 
President and Fellows of Harvard       SURGERY OF THE THYROID AND PARATHYROID GLANDS                     10,000
 College Massachusetts Eye and Ear
 Infirmary Depart of Otolaryngology
 
PRIME Education Inc. (PRIME)           ADVANCING OUR UNDERSTANDING OF THE IMMUNOLOGY AND                289,785
                                        TREATMENT CONSIDERATIONS IN ATOPIC DERMATITIS
 
ProCE, Inc. Wild Iris Medical          EVOLUTION OF MULTIPLE SCLEROSIS MANAGEMENT: PHARMACY'S           119,975
 Education, Inc.                        ROLE
 
Purdue University CiME LLC             APPLYING EVIDENCE BASED MANAGEMENT STRATEGIES FOR                 62,792
                                        PATIENTS WITH MS: AN EDUCATIONAL DATA CONTINUUM
 
Regents, University of California      FOURTH ANNUAL UCLA REVIEW OF CLINICAL NEUROLOGY                    5,000
 
Rheumatology Nurses Society American   RHEUMATOLOGY NURSES SOCIETY 2016 ANNUAL CONFERENCE                25,000
 Academy of Continuing Medical
 Education, Inc.
 
RMEI Postgraduate Institute for        A LEARNING PATHWAY IN ATOPIC DERMATITIS: ACHIEVING               989,750
 Medicine                               SUCCESS IN ASSESSMENT AND MANAGEMENT TO IMPROVE                        Collaboration \3\
                                        PATIENT OUTCOMES
 
RMEI The Omnia-Prova Education         TARGETING THE CYTOKINE PATHWAY IN RA MANAGEMENT:                 199,610
 Collaborative (TOPEC)                  IMPLICATIONS FOR NOVEL AND EMERGING IL-6 AGENTS                        Collaboration \3\
 
Robert Michael Educational Institute,  THE FUTURE OF ASTHMA MANAGEMENT: PRECISION THERAPY               212,340
 LLC                                    WITH EMERGING CYTOKINE INHIBITORS                                      Collaboration \3\
 
Sanford Medical Center Fargo           2016 SANFORD HEALTH NEPHROLOGY, DIALYSIS, TRANSPLANT               3,000
                                        SYMPOSIUM
 
Sidney Kimmel Medical College at       5TH ANNUAL DIABETES SYMPOSIUM: NEW ADVANCES & TRENDS              10,000
 Thomas Jefferson University
 
Society of Urologic Nurses and         EMERGING PRACTICE PATTERNS FOR THE UROLOGY NURSE IN               50,000
 Associates Plexus Communications       MANAGING PATIENTS WITH ADVANCED PROSTATE CANCER:
                                        CHALLENGES AND BEST PRACTICES WITH SYSTEMIC THERAPY
 
Southern Alliance for Physician        40TH ANNUAL SOUTHEASTERN CONSORTIUM FOR DERMATOLOGY               10,000
 Specialties CME                        UPDATES IN PSORIASIS AND INFLAMMATORY DISORDERS                        Collaboration \3\
 
Southern Salt, Water, and Kidney Club  57TH ANNUAL SCIENTIFIC MEETING                                     2,500
 
The Medical College of Wisconsin,      25TH ANNUAL PERSPECTIVES IN UROLOGY: POINT                        15,000
 Inc. Carden Jennings Publishing Co.,   COUNTERPOINT (PCP 25)
 Ltd.
 
Trustees of Boston University          2016 PCE ONCOLOGY SYMPOSIA SERIES FOR ADVANCED                   150,000
 Continuing Education Alliance          PRACTICE PROVIDERS SPECIALIZED IN ONCOLOGY: CHOOSING
                                        INITIAL THERAPY FOR METASTATIC PROSTATE CANCER: A NEW
                                        DIRECTION
 
Trustees of Boston University          PRACTICING CLINICIANS EXCHANGE (PCE) 2016 PRIMARY CARE            50,000
 Continuing Education Alliance, LLC     SYMPOSIA SERIES 3 FOR NURSE PRACTITIONERS & PHYSICIAN                  Collaboration \3\
                                        ASSISTANTS: RHEUMATOID ARTHRITIS: TREATING TO TARGET
                                        IN PRIMARY CARE
 
UMA Education, Inc. dba Global         SCRATCHING BENEATH THE SURFACE OF ATOPIC DERMATITIS               25,000
 Education Group                                                                                               Collaboration \3\
 
UMA Education, Inc. dba Global         METASTATIC PROSTATE CANCER: CURRENT TRENDS AND FUTURE             53,000
 Education Group Applied Clinical       LANDSCAPE
 Education
 
UMA MLG, LLC                           MANAGING MODERATE-TO-SEVERE ATOPIC DERMATITIS IN                 169,430
                                        ADULTS: PATHOLOGY-BASED, TARGETED THERAPIES                            Collaboration \3\
 
University of Cincinnati               INNOVATIVE TECHNIQUES: THE KNEE COURSE 2016                        5,000
 
University of Cincinnati CORE Medical  PRACTICE CHANGING ADVANCES: EXPANDING THE ATOPIC                 112,825
 Education, LLC                         DERMATITIS ARMAMENTARIUM                                               Collaboration\3\
 
University of Cincinnati CORE Medical  TYPE 2 DIABETES: MASTERING COMBINATION THERAPIES TO               42,825
 Education, LLC                         INDIVIDUALIZE AND OPTIMIZE OUTCOMES
 
University of Cincinnati Robert        TAILORING APPROACHES TO MANAGEMENT IN PATIENTS WITH              247,170
 Michael Educational Institute, LLC     RHEUMATOID ARTHRITIS: WHAT'S NEW?                                      Collaboration \3\
 
University of Nevada, Reno School of   2016 FALL CLINICAL DERMATOLOGY CONFERENCE                        125,000
 Medicine Foundation for Research and                                                                          Collaboration \3\
 Education in Dermatology
 
University of Tennessee Advanced       LYSIS CRISIS: PHARMACIST'S ROLE AND RESPONSIBILITY IN             70,000
 Studies in Medicine                    THE MANAGEMENT OF TUMOR LYSIS SYNDROME
 
University of Vermont and State        NORTHERN NEW ENGLAND NEUROLOGICAL SOCIETY ANNUAL                   5,000
 Agricultural College                   MEETING
 
WebMD Global LLC                       2016 CLINICAL COURSE ON NEW DEVELOPMENTS IN ATOPIC               144,200
                                        DERMATITIS                                                             Collaboration \3\
 
World Allergy Organization             WAO INTERNATIONAL SCIENTIFIC CONFERENCE 2016                      30,000
                                                                                                               Collaboration \3\
----------------------------------------------------------------------------------------------------------------
\1\ Applicant names are provided by the requestor. If applicants apply as a group for a single educational
  activity; all applicants may be not be identified above. The Company funds other educational activities
  (including fellowships and non-physician and patient education); all of which do not appear on this report,
  but appear on other reports on this site.
\2\ ``Funding Amount'' is the amount that the Company funded during Q4, 2016 identified above based upon an
  agreement. Recipients are required to return any unused funds. Information on unused funds returned by the
  applicant on activities are not reported. ``Funding Amount'' does not include funds that may have been
  provided by other affiliated Sanofi Company Entities (e.g., Sanofi Pasteur).
\3\ Collaboration (Shared) Funding--is the full amount of a grant funded under an agreement with Regeneron, some
  or all of which may be shared between the collaborating entities.


                                      Independent Medical Education Grants
                                           1st Jan 2017-31th Mar 2017
    Sanofi US and its affiliate Genzyme Corporation are committed to supporting independent medical education
  activities in therapeutic areas in which the Company is involved, for healthcare professionals, patients, and
   consumers to improve patient care and health outcomes in therapeutic areas in which the Company is engaged.
        Sanofi US and Genzyme Corporation are part of the Sanofi Group, a global pharmaceutical company.
----------------------------------------------------------------------------------------------------------------
                                                                                                 Funding Amount
        Recipient Name(s) \1\                              Activity Title                           ($) \2\
----------------------------------------------------------------------------------------------------------------
AcademicCME, LLC.                      Applying Newer Biologic Therapies to Improve Outcomes         324,370.00
                                        in Patients with Atopic Dermatitis                                     Collaboration \3\
 
Academy for Continued Healthcare       Current and Emerging Approaches to Customize Prostate          50,000.00
 Learning                               Cancer Treatment: an eNewsletter Series
 
Academy of Managed Care Pharmacy       Management of Rare and Orphan Diseases for Improved            34,500.00
 (AMCP)                                 Patient and Payer Outcomes
 
Advanced Studies in Medicine Elsevier  Hawaii Dermatology Seminar: A Therapeutic Update on           131,590.00
 Office of Continuing Medical           the Management of Patients with Atopic Dermatitis                      Collaboration \3\
 Education
 
Advancing Knowledge in Healthcare      Overcoming the Clinical Challenges of Basal Insulin           167,340.00
 Medtelligence                          Usage in Type 2 Diabetes
 
American Academy of PAs                AAPA 2017--Rheumatology Track                                   5,000.00
                                                                                                               Collaboration \3\
 
American Association of Clinical       Using Insulin When, Where, and How It's Needed: Type 2        204,570.00
 Endocrinologists                       Diabetes Treatment in the Modern Age
 
American Association of Clinical       AACE 2017--Treatment Advances for Challenging Patients        329,620.00
 Endocrinologists ASiM                  with Type 2 Diabetes: The Role of Emerging Insulin
                                        Combinations
 
American Association of Clinical       Endocrine University--Thyroid Sessions                         10,000.00
 Endocrinologists
 
American Association of Diabetes       Improving Adherence with New Fixed-Dose Insulin               864,525.00
 Educators Medscape                     Combination Therapy
 
American College of Cardiology         Recent Trends in Combination Therapy: Managing                 50,000.00
 Foundation                             Cholesterol Even in the Most Resistant                                 Collaboration \3\
 
American College of Medical Genetics   Genzyme/ACMG Foundation Clinical Genetics Fellowships          75,000.00
 Foundation                             in Medical Biochemical Genetics
 
American College of Rheumatology       2017 ACR Rheumatology Courses                                 150,000.00
                                                                                                               Collaboration \3\
 
American Society of Transplantation    2017 AST Cutting Edge of Transplantation: One                  38,000.00
                                        Transplant for Life, Many Pathways to Success
 
American Urological Association        2017 CRPC Live Forum for Urology Residents and Fellows         60,000.00
 
American Urological Association        2017 AUA Annual Meeting: Highlights in Advanced                75,000.00
                                        Prostate Cancer
 
Annenberg Center for Health Sciences   Chronic Kidney Disease-Mineral and Bone Disorder-              67,905.00
 at Eisenhower                          Translating Evidence Into Practice
 
Annenberg Center for Health Sciences   Expert Discussions: Recent Advances in Metastatic             100,000.00
 at Eisenhower Clinical Care Options,   Prostate Cancer Treatment
 LLC
 
Annenberg Center for Health Sciences   Dana Farber Master Class for Oncologists--                     25,000.00
 at Eisenhower                          Genitourinary Cancers Track
 
AXIS Medical Education                 Integrating Shared Decision Making and Guideline               40,000.00
                                        Recommendations for Prostate Cancer Treatment
 
AXIS Medical Education ReachMD         Advancing Interdisciplinary Care in Prostate Cancer:          143,090.00
                                        Clinical Updates for Urology and Oncology Healthcare
                                        Professionals
 
Boston University School of Medicine-- PCE Series 2: Decision Points--Considerations for             399,897.00
 Office of CME Continung Education      Using New Complementary GLP-1 Receptor Agonist-
 Alliance, LLC Institute for Medical    Insulin Combinations in Patients with T2DM
 and Nursing Education, Inc.
 
Boston University School of Medicine   PCE 2017 Primary Care Symposia Series 3: Joint                100,000.00
 Practicing Clinicians Exchange         Management: The Role of Primary Care in Rheumatoid                     Collaboration \3\
                                        Arthritis
 
Catamount Medical Education, LLC       MS4: Sequencing, Switching, Escalation, and Symptom           150,000.00
 Postgraduate Institute for Medicine    Management
 
Cedars-Sinai Medical Center            6th Annual Symposium on Lysosomal Storage Disorders            15,000.00
 
Children's Hospital of Philadelphia    Genetic Counselor Fellowship in Lysosomal Storage              75,000.00
 Foundation                             Disorders
 
Conquer Cancer Foundation of the       2017 Genitourinary (GU) Cancers Symposium: Translating         28,000.00
 American Society of Clinical           Research to Value-Based and Patient-Centric Care
 Oncology American Society of
 Clinical Oncology, Inc.
 
Consortium of Multiple Sclerosis       The Science of MS Management: 2017                             70,775.00
 Centers Nurse Practitioner
 Alternatives
 
Consortium of Multiple Sclerosis       Advances In Multiple Sclerosis (AIMS) 2016: A 360             125,000.00
 Centers Nurse Practitioner             Approach to Translating Data into Optimal Practice
 Alternatives The France Foundation
 
Duke University                        Fellowship in Medical Biochemical Genetics                     75,000.00
 
Elesevier Office of Continuing         Clinical Issues in Severe Asthma: Consensus and               271,605.00
 Education Integritas Communications    Controversies on the Road to Precision Medicine                        Collaboration \3\
 
Elsevier Office of Continuing Medical  Perspectives from the American Academy of Dermatology         131,590.00
 Education ASiM                         2017 Meeting: Clinical Strategies and Scientific                       Collaboration3
                                        Advances in Atopic Dermatitis
 
Emory Genetics Laboratory              Paul M. Fernhoff Genetic Counselor Fellowship in               75,000.00
                                        Lysosomal Storage Diseases
 
Endocrine Society                      ENDO 2017 Thyroid Sessions                                     75,000.00
 
Enquiring Minds, LLC Postgraduate      Multiple Sclerosis in Pediatric Patients: Expert               60,000.00
 Institute for Medicine                 Guidance on Overcoming Challenges in Diagnosis and
                                        Treatment
 
Evolve Medical Education, LLC          From Symptom Control to Target Treatment: The Shifting        201,325.00
                                        Paradigm of Atopic Dermatitis                                          Collaboration \3\
 
Excerpta Medica BV Elsevier Office of  2017 Genitourinary Cancers Symposium: A Therapeutic            65,795.00
 Continuing Medical Education           Update on the Management of Patients with Prostate
                                        Cancer
 
Foundation of the Consortium of MS     2017 FCMSC Medical Resident Annual Meeting (CMSC)              24,700.00
 Centers                                Scientific Scholarships
 
Foundation of the Consortium of MS     2017-2018 Medical Student Research Scholarships                34,000.00
 Centers
 
Haymarket Medical Education            Physiologic Approaches to Optimizing Glycemic Control:        309,519.00
                                        A Pecha Kucha-Inspired CME Symposium on Long-Acting
                                        Insulins
 
Horizon CME                            Fixed-Ratio GLP-1RA and Basal Insulin Formulations:           182,100.00
                                        How and When to Use Them?
 
Horizon CME                            GLP-1 RA and Basal Insulin Combinations: New Options          212,645.00
                                        for Treatment Intensification
 
Integrity Continuing Education, Inc.   Overcoming Barriers to the Early Recognition and              149,000.00
                                        Diagnosis of Rheumatoid Arthritis in Real-World                        Collaboration \3\
                                        Practice: Strategies to Expedite Treatment to
                                        Remission
 
Integrity Continuing Education, Inc.   2017 AAFP State Society CME Meetings and Publication          198,500.00
                                        in Action Enduring Material Initiative--Evaluating                     Collaboration \3\
                                        Newer Targeted Therapies for Patients with Rheumatoid
                                        Arthritis: Addressing Unmet Needs in the Primary Care
                                        Practice
 
International Psoriasis Council        Evolving Perspectives on Psoriasis and Atopic                 100,000.00
                                        Dermatitis: Are They Two Diseases or One Spectrum?                     Collaboration \3\
 
Lysosomal and Rare Disorders Research  Genetic, Rare and Immune Disorders Symposium (GRIDS)           30,000.00
 and Treatment Center Professional      2016
 Education Services Group
 
Med Learning Group                     Actionable Pathologic Targets in Rheumatoid Arthritis:        169,700.00
                                        Modifying the Dysregulation of the Immune Response to                  Collaboration \3\
                                        Self to Optimize Patient Outcomes
 
Medical Learning Institute Inc. PVI    ``Insights Into the Pathophysiology of Atopic                 290,600.00
 Peerview Institute for Medical         Dermatitis: Setting the Stage for Novel Treatment                      Collaboration \3\
 Education Inc.                         Options''
 
Medical Learning Institute Inc. PVI    ``Addressing Unmet Needs in Rheumatoid Arthritis              156,730.00
 Peerview Institute for Medical         Through Novel Treatment Options and Enhanced                           Collaboration \3\
 Education Inc.                         Physician-Patient Collaboration''
 
Medical Learning Institute Inc. PVI,   PeerView Video in Exchange, ``Establishing a                   98,750.00
 PeerView Institute for Medical         Therapeutic Alliance in the Management of Multiple
 Education                              Sclerosis: How Can We Better Align Treatment
                                        Preferences and Goals among Patients and
                                        Practitioners?''
 
Med-IQ, LLC                            Newborn Screening for Lysosomal Storage Disorders:            197,866.00
                                        Recent Progress and Unanswered Questions
 
Med-IQ, LLC                            Medical Insiders: Targeting IL-6 Signaling in the             125,000.00
                                        Treatment of Rheumatoid Arthritis                                      Collaboration3
 
Med-IQ, LLC                            Tumor Lysis Syndrome in a Rapidly Evolving Treatment          142,099.00
                                        Landscape
 
Med-IQ, LLC                            Insulin Intensification with GLP-1 Receptor Agonists:         251,110.00
                                        Clinical Evidence and Real World Perspectives
 
Med-IQ, LLC                            Viewpoints on Atopic Dermatitis: How Emerging                 169,995.00
                                        Treatments May Change the Management of Moderate to                    Collaboration \3\
                                        Severe Disease
 
Medscape                               Osteoarthritis of the Knee: A Patient-Simulation              250,000.00
                                        Approach to Assessment and Management
 
Medscape LLC                           Managing Patients With Rheumatoid Arthritis in the            250,000.00
                                        Virtual Clinic Setting                                                 Collaboration \3\
 
Medscape LLC                           A Lipid Clinic in Action: How Would You Treat?                225,000.00
                                                                                                               Collaboration \3\
 
Medscape LLC Close Concerns            Improving Outcomes in Diabetes: Glucose Monitoring,            75,000.00
                                        Adherence, and Individualized Treatment
 
Medscape, LLC                          Autologous Stem Cell Transplantation in Multiple              182,500.00
                                        Myeloma: Who, When, and How?
 
Mount Sinai School of Medicine         International Center for Fabry Disease                        150,000.00
 
MS Cure Fund, Inc.                     1st Quarter 2017 Multiple Sclerosis Lifestyle                  19,750.00
                                        Management Patient Education Programs
 
National Association of Managed Care   Managing Castration-Resistant Prostate Cancer:                 45,000.00
 Physicians                             Understanding the Therapeutic Landscape
 
National Association of Managed Care   What's New in the Evolving Treatment Landscape for             57,000.00
 Physicians, Inc.                       Moderate-to-Severe Atopic Dermatitis (AD)                              Collaboration \3\
 
National Jewish Health                 Personalized Medicine in Severe Asthma: Applying              120,044.00
                                        Emerging Data and Treatments to Everyday Clinical                      Collaboration \3\
                                        Practice
 
National Jewish Health Western         WSAAI 55th Annual Scientific Session                           15,000.00
 Society of Allergy, Asthma and                                                                                Collaboration \3\
 Immunology (WSAAI)
 
National Lipid Association Robert      Navigating the Challenges of Prescribing PCSK9                249,835.00
 Michael Educational Institute (RMEI)   Inhibitors in Persistent Elevated LDL-C                                Collaboration \3\
 
National Society of Genetic            New Lysosomal Storage Disease Healthcare Advocate              28,000.00
 Counselors (NSGC) Emory University     Workshop
 
New York University--Langone School    Department of Neurology, Division of Neurogenetics             75,000.00
 of Medicine
 
North American Center for Continuing   Fixed-Ratio GLP-1 RA and Basal Insulin Combinations: A        173,365.00
 Medical Education Horizon CME          Complementary Approach to Treatment Intensification
 
Norton Healthcare Foundation           Celebrating MS Innovations 2017                                10,000.00
 
NYU Post-Graduate Medical School       NYU Seminar In Advanced Rheumatology                           10,000.00
                                                                                                               Collaboration \3\
 
Organ Donation and Transplantation     2017 National Donor Management Summit                           5,000.00
 Alliance
 
Penn State College of Medicine MCM     Evolving Standards of Care in Metastatic Prostate             138,400.00
 Education                              Cancer
 
Penn State College of Medicine PVI     ``PeerView Master Class and Practicum Live--Urologists        150,000.00
 Peerview Institute for Medical         at the Intersection of Evidence-Based and Patient-
 Education Inc.                         Centric Prostate Cancer Care: Practical Guidance for
                                        Everyday Practice''
 
Penn State College of Medicine, MCM    Rheumatoid Arthritis: Improving Quality of Care               100,000.00
 Education                                                                                                     Collaboration \3\
 
Pharmacy Times Continuing Education    Managing Diabetes with Insulin/ GLP-1 Receptor Agonist        251,500.00
                                        Combinations: A Clinical Discussion of Safety and
                                        Efficacy Data
 
Pharmacy Times Continuing Education    Information for Pharmacists: Counseling on                     36,000.00
                                        Dermatologic Conditions                                                Collaboration \3\
 
Pharmacy Times Continuing Education    Advances in the Treatment of Moderate to Severe Atopic         59,867.00
                                        Dermatitis: Practice and Management Essentials for                     Collaboration \3\
                                        Specialty Pharmacists
 
Pharmacy Times Continuing Education    Medical Crossfirer: Value-Based Diabetes: Managing            187,400.00
                                        Costs Yet Improving Outcomes
 
Pharmacy Times Continuing Education    Treatment Advances in Diabetes: Evaluating the Safety          68,000.00
                                        and Efficacy of Insulin/GLP-1 Receptor Agonist
                                        Combinations
 
Pharmacy Times Continuing Education    Atopic Dermatitis: Focusing on the Patient Care                74,000.00
                                        Strategy in the Managed Care Setting                                   Collaboration \3\
 
Ponce Medical School Foundation, Inc.  The Role of the Primary Care Providers with Chronic            10,000.00
                                        Kidney Disease Patients.
 
Postgraduate Healthcare Education,     Working Together Against Clinical Inertia: Using              126,075.00
 LLC                                    Combination Injectable Therapies in Type 2 Diabetes
 
Postgraduate Institute for Medicine    Best Practice Roadmaps and Clinical Rationale for Use         968,000.00
 CMEducation Resources                  of Complementary Insulin plus GLP-1 Receptor Agonist
                                        Combination Therapy To Optimize PAN-Glycemic HA1c
                                        Target Goal Attainment in T2D: The Physiologic and
                                        Mechanistic Basis for New Basal Insulin plus Short-
                                        Acting GLP-1 RA Fixed-Ratio, Combination Formulations
                                        for Controlling FPG and Postprandial Hyperglycemia
                                        (PPG): Optimizing Glucose Control and Reducing Risks
                                        of Hypoglycemia and Weight Gain
 
Postgraduate Institute for Medicine    Best Practice Roadmaps and Clinical Rationale for Use         319,000.00
 CMEducation Resources                  of Complementary Insulin plus GLP-1 Receptor Agonist
                                        Combination Therapy To Optimize PAN-Glycemic HA1c
                                        Target Goal Attainment in T2D: The Physiologic and
                                        Mechanistic Basis for New Basal Insulin plus Short-
                                        Acting GLP-1 RA Fixed-Ratio, Combination Formulations
                                        for Controlling FPG and Postprandial Hyperglycemia
                                        (PPG): Optimizing Glucose Control and Reducing Risks
                                        of Hypoglycemia and Weight Gain
 
Postgraduate Institute for Medicine    New Fixed-Ratio Combination Insulin Regimens for              341,000.00
 CMEducation Resources                  Optimizing Comprehensive Glycemic Management In
                                        Challenging Patients with T2D: The Rationale,
                                        Evidence, and Mechanistic Basis for Fixed Ratio,
                                        Complementary Insulin plus GLP-1 RA Combinations for
                                        Achieving FPG and PPG Target Goals-Focus on Pan-
                                        Glycemic Control While Mitigating Risks of
                                        Hypoglycemia and Weight Gain
 
Practicing Clinicians Exchange         Practicing Clinicians Exchange (PCE) Directed Learning        138,800.00
 Continuing Education Alliance          eCourse: Updates on the Management of Knee
                                        Osteoarthritis in Primary Care: The Role of
                                        Viscosupplementation
 
President and Fellows of Harvard       New England Thyroid Club                                        1,500.00
 College acting through Harvard
 Medical School Depart. of Contin Edu
 Beth Israel Deaconess Medical Center
 
President and Fellows of Harvard       Clinical Endocrinology 2017                                     5,000.00
 College acting through the Harvard
 Medical School Department of Con The
 Massachusetts General Hospital
 
PRIME Education, LLC                   GME-CME Today Advanced Practice in Multiple Sclerosis:         92,938.00
                                        Focused Training for Effective Individualized
                                        Treatment Decision-Making
 
PRIME Education, LLC                   Implications of Cardiovascular Outcomes Trials on             228,145.00
                                        Lipid-Lowering Therapies                                               Collaboration \3\
 
PRIME Education, LLC                   Applying Evidence and Lessons Learned in the                  295,270.00
                                        Management of Moderate-to-Severe Atopic Dermatitis                     Collaboration \3\
 
Pri-Med Institute, LLC Horizon CME     Practical Strategies to Using Novel GLP-1 RA and Basal        972,120.00
                                        Insulin Combinations in Clinical Practice
 
Pri-Med Institute, LLC Horizon CME     Integrating Newer Basal Insulins in Primary Care: A           956,499.91
                                        Case-based Review
 
Projects In Knowledge @Point of Care   Rheumatologic Diseases @Point of Care                         150,000.00
                                                                                                               Collaboration \3\
 
Projects In Knowledge @Point of Care   Multiple Sclerosis @Point of Care                             133,225.00
 
Prostate Cancer Foundation              MARS2 Retreat (Mission: Androgen Receptor Splice              10,000.00
                                        Variant)
 
PVI Peerview Institute for Medical     PeerView Video inSession, ``Examining the Clinical             66,240.00
 Education Inc. Medical Learning        Implications of Late-Breaking Data on Approved and
 Institute Inc.                         Emerging Disease Modifying Therapies for Multiple
                                        Sclerosis Management: What Are the Key Learnings From
                                        Boston?''
 
Regents of the University of           5th Annual UC San Diego Essentials and Advances in              5,000.00
 California                             Apheresis
 
Regents of the University of           Transplant Immunosuppression 2017: Achieving Long-Term         35,000.00
 Minnesota                              Success
 
Research To Practice                   What Urologists Want to Know: Addressing Current               85,000.00
                                        Questions and Controversies in the Management of
                                        Early and Advanced Prostate Cancer--An Independent
                                        Satellite Symposium (ISS) Held in Conjunction with
                                        the 2017 American Urological Association (AUA) Annual
                                        Meeting
 
Rocky Mountain MS Center               MS 101 2017 Programs                                           10,000.00
 
Rush University Medical Center Plexus  Realizing Improved Outcomes in Advanced Prostate               80,000.00
 Communications                         Cancer through Evolving Research and Emerging
                                        Treatment Paradigms: Challenges and Opportunities
 
Rush University Medical Center Plexus  VHA Oncology Clinical Forums: ``Current Treatment             100,000.00
 Communications                         Strategies for Advanced Prostate Cancer: Sequencing
                                        Therapies and Incorporating Novel Approaches''
 
Society for Inherited Metabolic        2016 North American Metabolic Academy                          20,000.00
 Disorders
 
St. Joseph's Regional Medical Center   Introduction to Clinical Transplantation; Renal                 1,500.00
                                        Transplantation--An Overview
 
The France Foundation                  State Chapter Meetings: A Physiological Approach to           357,120.00
                                        Combination Therapies: Improving Glycemic Control in
                                        T2DM
 
The France Foundation                  A Bright Outlook on New and Emerging RA Management            145,330.00
                                        Options: What Would You Do?                                            Collaboration \3\
 
The France Foundation Calibre          Famous People with Diabetes: A Case Study Exploring           552,210.00
 Institute for Quality Medical          the Use of New and Emerging Basal Insulins
 Education
 
The Medical College of Wisconsin,      27th International Prostate Cancer Update                      20,000.00
 Inc. Carden Jennings Publishing Co.,
 Ltd.
 
The Medical College of Wisconsin,      Optimizing Stem Cell Mobilization for Autologous              223,000.00
 Inc. Carden Jennings Publishing Co.,   Transplantation in Myeloma
 Ltd.
 
The National Multiple Sclerosis        The Living Well with MS Conference (North Florida)              3,500.00
 Society, North Florida Chapter
 
The Trustees of the University of      Lysosomal Storage Disease Fellowship                           75,000.00
 Pennsylvania
 
The University of Chicago              22nd Annual University of Chicago Developmental                 5,000.00
                                        Therapeutics Symposium
 
The University of Texas MD Anderson    7th Current Concepts in the Management of Thyroid &            25,000.00
 Cancer Center                          Parathyroid Neoplasms
 
Tufts Medical Center                   Hypertrophic Cardiomyopathy--A Contemporary and                20,000.00
                                        Treatable Disease: Diagnosis, Heart Failure
                                        Management, and Prevention of Sudden Death
 
UC Irvine                              University of California, Irvine Lysosomal Storage             56,857.68
                                        Diseases Patient and Family Educational Grant
 
UCI Office of Continuing Medical       Nephrology Grand Rounds                                         2,000.00
 Education University of California
 Irvine
 
UMA Education Inc., dba Global         Optimizing Outcomes in Atopic Dermatitis                      106,250.00
 Education Group, Physicians'                                                                                  Collaboration \3\
 Education Resource
 
University of Alabama at Birmingham    2017 Fabry Fellowship                                          75,000.00
 
UMA Education, Inc.: dba Global        Going Deeper on Atopic Dermatitis: Pathophysiology to         239,640.92
 Education Integritas Communications    the Management of Moderate-to-Severe Disease                           Collaboration \3\
 
University of Arkansas for Medical     Tackling Type 2 Diabetes at the Community Level: A             90,000.00
 Sciences MedIQ                         Focused QI Initiative to Overcome Local Challenges to
                                        Patient Health
 
University of Cincinnati Advances in   MauiDerm 2017                                                  45,000.00
 Cosmetic and Medical Dermatology                                                                              Collaboration \3\
 
University of Kansas Medical Center/   Neuromuscular Review Course 2017                               20,000.00
 Kansas Endowment Association
 
University of Kansas School of         Neuromuscular Medicine Fellowship                              75,000.00
 Medicine
 
University of Massachusetts Medical    The Physiologic and Mechanistic Rationale for                 341,000.00
 School CMEducation Resources           Achieving HA1c Target Goals with Basal Insulin In
                                        Vulnerable Patients with Type 2 Diabetes: Focus on
                                        the Safety-Efficacy Equation, Patient Selection,
                                        Switching, Dosing and Physiologic, PK/PD Profiles of
                                        Long-Acting Basal Insulin Formulations
 
University of Massachusetts Medical    The iQ&A Case-By-Case interactive Diabetes                    178,000.00
 School CMEducation Resources           Intelligence Zone: Practical, Real World Strategies
                                        for Deploying Fixed-Ratio Insulin Combinations in T2D-
                                        National Experts in Diabetes Focus on Patient
                                        Identification, Dose Titration, Pan-Glycemic (FPG and
                                        PPG) Control, Mechanistic Complementarity, and
                                        Optimizing the Safety-Weight-Efficacy Equation in
                                        Patients with Diabetes
 
University of Massachusetts Medical    The iQ&A Case-By-Case Interactive Diabetes                    178,000.00
 School CMEducation Resources           Intelligence Zone: Focus on Practical Aspects of
                                        Using Physiologic, Long-Acting Basal Insulin to
                                        Optimize Glycemic Management in T2D
 
University of Rochester School of      2017 Society for Investigative Dermatology Annual              50,000.00
 Medicine and Dentistry Society for     Meeting                                                                Collaboration \3\
 Investigative Dermatology
 
University of Massachusetts Medical    The iQ&A Case-By-Case Interactive Diabetes                    178,000.00
 School CMEducation Resources           Intelligence Zone: Focus on Practical Aspects of
                                        Using Physiologic, Long-Acting Basal Insulin to
                                        Optimize Glycemic Management in T2D
 
University of Rochester School of      2017 Society for Investigative Dermatology Annual              50,000.00
 Medicine and Dentistry Society for     Meeting                                                                Collaboration3
 Investigative Dermatology
 
University of Vermont and State        The 28th Annual Eastern Winter Dermatology Conference                   Collaboration \3\
 Agricultural Colle                     10,000.00
 
UT Southwestern Medical Center         39th Annual Carrell-Krusen Neuromuscular Symposium              5,000.00
                                                                                                               Collaboration \3\
 
World Allergy Organization             Collaboration on Severe Asthma (COSA)                          35,000.00
                                                                                                               Collaboration \3\
----------------------------------------------------------------------------------------------------------------
\1\ Applicant names are provided by the requestor. If applicants apply as a group for a single educational
  activity; all applicants may be not be identified above. The Company funds other educational activities
  (including fellowships and non-physician and patient education); all of which do not appear on this report,
  but appear on other reports on this site.
\2\ ``Funding Amount'' is the amount that the Company funded during Q1, 2017 identified above based upon an
  agreement. Recipients are required to return any unused funds. Information on unused funds returned by the
  applicant on activities are not reported. ``Funding Amount'' does not include funds that may have been
  provided by other affiliated Sanofi Company Entities (e.g., Sanofi Pasteur).
\3\ Collaboration (Shared) Funding--is the full amount of a grant funded under an agreement with Regeneron, some
  or all of which may be shared between the collaborating entities.


                                      Independent Medical Education Grants
                                          1st April 2017-30th June 2017
    Sanofi US and its affiliate Genzyme Corporation are committed to supporting independent medical education
  activities in therapeutic areas in which the Company is involved, for healthcare professionals, patients, and
   consumers to improve patient care and health outcomes in therapeutic areas in which the Company is engaged.
        Sanofi US and Genzyme Corporation are part of the Sanofi Group, a global pharmaceutical company.
----------------------------------------------------------------------------------------------------------------
                                                                                                 Funding Amount
        Recipient Name(s) \1\                              Activity Title                           ($) \2\
----------------------------------------------------------------------------------------------------------------
AKH Inc., Advancing Knowledge in       A Multidisciplinary Approach to the Treatment of              149,125.00
 Healthcare Center of Excellence        Prostate Cancer: Providing Therapies that Improve
 Media, LLC--An affiliate of The Lynx   Overall Survival and Quality of Life
 Group
 
AKH Inc., Advancing Knowledge in       Endocrine Nurses Society Symposium 2017 Thyroid                 5,000.00
 Healthcare Endocrine Nurses Society    Sessions
 
American Academy of Dermatology The    The Future is Finally Here--Targets of the New Atopic          75,000.00
 France Foundation                      Dermatitis Drugs                                                       Collaboration \3\
 
American Academy of PAs                AAPA 2017--Orthopaedics Track                                  10,000.00
 
American Association of Clinical       Current Landscape in Medullary Thyroid Cancer: Updates        198,425.00
 Endocrinologists                       for Clinicians
 
American Association of Clinical       Georgia-AACE April Dinner Program: New Developments in          3,276.00
 Endocrinologists                       Thyroid Cancer
 
American College of Allergy, Asthma &  EAC 2017 Update in Allergy, Asthma & Immunology                10,000.00
 Immunology Eastern Allergy                                                                                    Collaboration \3\
 Conference
 
American College of Allergy, Asthma &  Society of Allergy, Asthma & Immunology CSAAI 2017 A           10,000.00
 Immunology; California                 Midsummer Night's Wheeze
 
American College of Medical Genetics   Genzyme/ACMG Foundation Clinical Genetics Fellowships          75,000.00
 Foundation                             in Biochemical Genetics
 
American Society of Clinical           Oncology 2017 ASCO Annual Meeting Genitourinary Cancer         28,000.00
 Oncology, Inc. Conquer Cancer          Tracks Bundle--Prostate and Nonprostate
 Foundation of the American Society
 of Clinical
 
American Thoracic Society              ATS 2017 International Conference--Selected Sessions           20,000.00
                                        in Asthma                                                              Collaboration \3\
 
Ann & Robert H. Lurie Children's       Lysosomal Storage Disease Training Program for Genetic         75,000.00
 Hospital of Chicago                    Counselors
 
Med Learning Group                     Novel Formulations of Basal Insulins for Patients with        249,050.00
                                        Diabetes: A New Opportunity to Optimize Outcomes
 
Med Learning Group                     A Virtual Reality View of Biologic Agents: Targeted           375,000.00
                                        Therapies for the Management of Moderate-to-Severe                     Collaboration \3\
                                        Atopic Dermatitis in Adults
 
Medical Learning Institute Inc. PVI     Enhancing Autologous Hematopoietic Stem Cell                 108,050.00
 Peerview Institute for Medical         Transplantation Through Individualized Stem Cell
 Education Inc.                         Mobilization Strategies
 
Medical Learning Institute Inc. PVI     PeerView Video in Session ``New Developments in              154,980.00
 Peerview Institute for Medical         Inflammatory Dermatologic and Respiratory Diseases:                    Collaboration \3\
 Education Inc.                         Clinical Highlights From Helsinki''
 
Medscape LLC                           Basal Insulin in Today's Clinical Practice                    500,000.00
                                        Environment: Improving Use for Better Patient
                                        Outcomes
 
Medscape LLC                           Clinical Advances in Atopic Dermatitis                        950,000.00
                                                                                                               Collaboration \3\
 
Medscape LLC                           A Medscape Studio Series on Modern Approaches for             125,000.00
                                        Optimizing Care in MS
 
Michigan State Medical Society         Rheumatology Update                                             5,000.00
                                                                                                               Collaboration \3\
 
MSWorld Inc.                           Comprehensive Proposal for 2017 MS World Conference            50,000.00
                                        Coverage
 
MSWorld Inc.                           2017 ``MSWorld Talks'' Series                                  55,000.00
 
Muscular Dystrophy Association         MDA Care Center Open House at Nemours Children's                  500.00
                                        Hospital
 
National Association of Managed Care   Individualizing Treatment in the Management of Type 2          57,000.00
 Physicians, Inc.                       Diabetes: Novel Therapies for Improved Patient
                                        Outcomes
 
National Comprehensive Cancer Network  Prostate Cancer Patient Management Simulator                   35,000.00
 
National Lipid Association Vindico     Back to the Future: Clinical Experience with and               50,000.00
 Medical Education                      Access to Lipid-Lowering Agents of the Past, Present,                  Collaboration \3\
                                        and Future--A National Lipid Association Expert
                                        Discussion and Town Hall
 
National Medical Association           Endocrinology, Diabetes, and Metabolism Symposium             250,000.00
                                        Current and Emerging Interventions: Saving Lives and
                                        Limbs by Improving Diabetes Care
 
National Medical Association           MODERN ERA DIAGNOSIS, TREATMENT AND MANAGEMENT OF              15,000.00
                                        PATIENTS WITH PROSTATE CANCER
 
National Multiple Sclerosis Society    National MS Society Monthly Email Newsletter                   75,000.00
 
National Society for Cutaneous         2017 Real World Dermatology for Residents                      40,000.00
 Medicine                                                                                                      Collaboration \3\
 
OhioHealth                             OhioHealth Multiple Sclerosis Symposium                         5,000.00
 
Oncology Nursing Society               42nd ONS Annual Congress and two Oncology Updates              25,000.00
                                        Regional Programs
 
Oregon Health & Science University     7th International Symposium on Gait & Balance in               13,108.00
                                        Multiple Sclerosis: Neuroplasticity and
                                        Rehabilitation in MS
 
Palm Beach County Medical Society      Managing Thyroid Disease for the Primary Care Provider          5,000.00
 Services Palm Beach Diabetes &
 Endocrine Specialists, P.A.
 
Penn State College of Medicine i3      Selecting Optimal Therapeutic Strategies for Patients          50,000.00
 Health                                 With Differentiated and Medullary Thyroid Cancer
 
Penn State College of Medicine PVI     ``Science and Stories: Making the Most of the Complex         146,030.00
 PPerview Institute for Medical         Treatment Landscape in Prostate Cancer''
 Education Inc.
 
Pharmacy Times Continuing Education    Reaching Out: A Pharmacist's Curriculum to Optimize           251,240.00
                                        Insulin Therapy Through Patient Engagement and
                                        Management
 
Postgraduate Healthcare Education,     How Specialty Pharmacists Can Enhance Patient-Driven           58,000.00
 LLC Postgraduate Institute for         Care in Multiple Sclerosis
 Medicine
 
Postgraduate Healthcare Education,     Providing Relief to Patients with Atopic Dermatitis:          137,250.00
 LLC Postgraduate Institute for         How Pharmacists Can Help                                               Collaboration \3\
 Medicine
 
Potomac Center for Medical Education   MULTIPLE SCLEROSIS CARE IN THE HOSPITAL SETTING: Novel         75,000.00
 Rockpointe Corporation                 Neuroimaging Techniques, Individualized Treatment
                                        Strategies, and Management of Comorbidities
 
Practicing Clinicians Exchange Boston  New and Emerging Strategies in T2DM Using Basal               375,000.00
 University School of Medicine          Insulin
 
PRIME Education, LLC                   Advances in Psoriatic Diseases and Atopic Dermatitis          150,000.00
                                        for Clinicians in Federal and Public Healthcare                        Collaboration \3\
                                        Settings
 
PRIME Education, LLC                   When Statin Therapy Isn't Enough                              192,435.00
                                                                                                               Collaboration \3\
 
ProCE Inc.                             Atopic Dermatitis: A Specialty Pharmacy 360-Degree             42,250.00
                                        View of the Patient                                                    Collaboration \3\
 
Projects In Knowledge                  MedImages Cases: Multiple Sclerosis                           125,000.00
 
Purdue University MCM Education        Managing Type 2 Diabetes: The Role of Insulin                 175,000.00
 
Regents of the University of Colorado  Practical Ways to Achieve Targets in Diabetes Care            150,000.00
 
Regents of the University of           Pharmacotherapy of Inherited Metabolic Diseases Post-          75,000.00
 Minnesota                              Doctoral PharmD Fellowship
 
Society for Translational Oncology     Conference Perspectives: Lessons Learned                       40,000.00
 
St. Vincent Neuroscience Institute,    MS: A Personal Approach                                         3,000.00
 St. Vincent Hospital, Indianapolis
 
The University of Chicago MCM          Evolving Paradigms for Insulin Therapy of Type 2              150,000.00
 Education                              Diabetes
 
Tisch Multiple Sclerosis Research      Tisch MS Research Center 20th Annual MS Patient                50,000.00
 Center of New York                     Symposium
 
UMA Education Inc., dba Global         Coalition United for Better Eczema Care (CUBE-C)              320,000.00
 Education Group FactoRx Health                                                                                Collaboration \3\
 Advocacy Partners National Eczema
 Association Med Ed Consulting
 
UMA Education Inc., dba Global         R.A.P.I.D.--Rheumatoid Arthritis: A Primary Care             150,000.00
 Education Group FactoRx MedEd          Initiative for Improved Diagnosis and Outcomes                         Collaboration \3\
 Consulting Improve CME, LLC Indegene
 
UMA Education Inc., dba Global         The Role of Concentrated Insulins and Insulin                 127,500.00
 Education Group Physicians'            Combinations in Overcoming Insulin Resistance and
 Education Resource                     Improving Adherence A Patient Centered
                                        Multidisciplinary Approach
 
UMA Education Inc., dba Global         Medical Crossfirer: Advances in Atopic Dermatitis: A          157,000.00
 Education Group Physicians'            Multidisciplinary, Patient-Centered Approach to
 Education Resources                    Addressing Unmet Therapeutic Needs
 
UMA Education Inc., dba Global         Effective Management of Atopic Dermatitis: New                 99,585.00
 Education Group Physicians'            Approaches to Guiding Everyday Practice                                Collaboration \3\
 Education Resources
 
UMA Education Inc., dba Global         Getting Beneath the Surface in Atopic Dermatitis: A           164,330.00
 Education Group Physicians'            Patient-Centered Approach to Optimize Outcomes                         Collaboration \3\
 Education Resources
 
UMA Education, Inc. dba Global         Best Practices: Efficient and Cost Effective                  155,884.00
 Education Group Tarsus Cardio Inc.     Management of the Authorization Process                                Collaboration \3\
 dba Cardiometabolic Health Congress
----------------------------------------------------------------------------------------------------------------
\1\ Applicant names are provided by the requestor. If applicants apply as a group for a single educational
  activity; all applicants may be not be identified above. The Company funds other educational activities
  (including fellowships and non-physician and patient education); all of which do not appear on this report,
  but appear on other reports on this site.
\2\ ``Funding Amount'' is the amount that the Company funded during Q2, 2017 identified above based upon an
  agreement. Recipients are required to return any unused funds. Information on unused funds returned by the
  applicant on activities are not reported. ``Funding Amount'' does not include funds that may have been
  provided by other affiliated Sanofi Company Entities (e.g., Sanofi Pasteur).
\3\ Collaboration (Shared) Funding--is the full amount of a grant funded under an agreement with Regeneron, some
  or all of which may be shared between the collaborating entities.


                                      Independent Medical Education Grants
                                          1st July 2017--30th Sep 2017
    Sanofi US and its affiliate Genzyme Corporation are committed to supporting independent medical education
  activities in therapeutic areas in which the Company is involved, for healthcare professionals, patients, and
   consumers to improve patient care and health outcomes in therapeutic areas in which the Company is engaged.
        Sanofi US and Genzyme Corporation are part of the Sanofi Group, a global pharmaceutical company.
----------------------------------------------------------------------------------------------------------------
                                                                                                 Funding Amount
        Recipient Name(s) \1\                              Activity Title                           ($) \2\
----------------------------------------------------------------------------------------------------------------
American Academy of PAs                2017 Adult Hospital Medicine Boot Camp                          5,490.00
 
American Association of Clinical       Current Landscape in Medullary Thyroid Cancer: Updates        147,769.00
 Endocrinologists                       for Clinicians
 
American Association of Clinical       Illinois-AACE 7th Annual Meeting                                5,000.00
 Endocrinologists
 
American Association of Clinical       New Jersey Chapter of the American Association of               5,000.00
 Endocrinologists                       Clinical Endocrinologists
 
American College of Allergy, Asthma &  Thursday Morning Session: Atopic Dermatitis Yardstick          40,000.00
 Immunology                                                                                                    Collaboration \3\
 
American College of Medical Genetics   Genzyme ACMG Foundation Clinical Genetics Fellowships          75,000.00
 Foundation                             in Biochemical Genetics
 
American Society of Transplant         11th Annual Surgical Fellows Symposium                         44,500.00
 Surgeons
 
American Society of Transplantation    2017 Fellows Symposium on Transplantation                      40,000.00
 
American Urological Association        Practical Management of Metastatic Prostate Cancer:            75,000.00
                                        Guidelines and Beyond
 
Ann & Robert H. Lurie Children's       Lysosomal Storage Disease Training Program for Genetic         75,000.00
 Hospital of Chicago                    Counselors
 
Ascendant Limited Albert Einstein      The Team-based Approach to Diagnosing and Managing            134,868.75
 College of Medicine and Montefiore     African American Patients with MS: A Quality
 Medical Center, Center for CME         Improvement Curriculum
 
Carden Jennings Publishing Co., Ltd.   27th International Prostate Cancer Update                      20,000.00
 The Medical College of Wisconsin,
 Inc.
 
Cleveland Clinic Educational           Pitfalls in Diagnosis of Multiple Sclerosis                    25,000.00
 Foundation
 
Clinical and Patient Educators         Oncology Emergency Essentials: Addressing Tumor Lysis         117,394.90
 Association                            Syndrome in Your Practice
 
Carden Jennings Publishing Co., Ltd.   27th International Prostate Cancer Update                      20,000.00
 The Medical College of Wisconsin,
 Inc.
 
Cleveland Clinic Educational           Pitfalls in Diagnosis of Multiple Sclerosis                    25,000.00
 Foundation
 
CMEducation Resources Postgraduate     Optimizing Insulin-Based Glycemic Control in Type 2           500,000.00
 Institute for Medicine                 Diabetes: The Foundational Role and Physiologic
                                        Rationale for Long-Acting Insulin: An Evidence-Based
                                        Roadmap for Clinical Success-Focus on the Safety-
                                        Efficacy and PK/PD Profiles of New Long-Acting
                                        Physiologic Insulin Formulations
 
Connecticut Pharmacists Association    Current and Emerging Therapies in Multiple Sclerosis           10,000.00
 
Continuing Education Alliance          PCE Interactive eCourse Series: New Pathways in Atopic        149,534.00
 Practicing Clinicians Exchange         Dermatitis: Novel Therapies for Optimizing Outcomes                    Collaboration \3\
 
Dignity Health MandatoryCE             2017 Arkansas Diabetes Symposium: Focus on Treatment           25,000.00
                                        Advances, Nutrition Therapy, Obesity and Metabolic
                                        Syndrome
 
DKBmed The Johns Hopkins University    The Johns Hopkins University School of Medicine               120,000.00
 School of Medicine                     eDiabetes Review Volume 3
 
Duke University                        Duke Solid Organ Transplant Summit                             30,000.00
 
E&S MedEd Group, Inc. American         Zeroing In on A1C Targets: Pinpointing the Optimal            284,660.00
 Association of Diabetes Educators      Basal Insulin Strategy in Every Patient with Type 2
                                        Diabetes
 
Elsevier Office of Continuing          Evolving Treatment Paradigms for Rheumatoid Arthritis:         75,000.00
 Education Integritas Communications    Translating Comprehensive Patient Evaluations Into                     Collaboration \3\
                                        Personalized Therapy
 
Elsevier Office of Continuing Medical  MS Paris 2017: Clinical Updates on Disease Modifying          161,920.00
 Education AcademicCME                  Therapies to Improve Outcomes for Patients with
                                        Multiple Sclerosis
 
Enquiring Minds, LLC Postgraduate      Are My Patients Taking Their Meds as Prescribed?              106,205.00
 Institute for Medicine                 Addressing Suboptimal Therapeutic Response Among
                                        Patients with MS
 
Euforea IVZW                           European Summit on the Prevention and Self-Management          10,676.50
                                        of Airway Diseases
 
Excel Continuing Education             Expanding Horizons in ASMD/Niemann-Pick Disease                68,175.00
 
Focus Medical Communications, LLC      2017 International Coalition of Rheumatology Education        100,000.00
 Siyemi Learning                        Providers Initiative
 
Foundation for Orthopaedic Research &  2017 Orthopaedics for the Primary Care Practitioner &           5,000.00
 Education (FORE)                       Rehabilitation
 
Global Academy Medical Education       Innovative Techniquesr: The Knee, Hip and Shoulder             25,000.00
 University of Cincinnati               Course
 
Haymarket Medical Education Haymarket  Race to Remission: Timely Diagnosis and Early,                273,823.00
 Media/MIMS                             Intensive Treatment in Rheumatoid Arthritis Care: A                    Collaboration \3\
                                        Patient-Centered Global Curriculum Aligning With the
                                        Spirit of World Arthritis Day
 
Indiana Academy of Physician           ``Multiple sclerosis 2017--Update on diagnostic                 5,000.00
 Assistants                             criteria, clinical descriptors, and treatments''
 
International Niemann-Pick Disease     Support for the development and management of the             117,706.45
 Registry                               International Niemann Pick Disease Registry
 
Kentucky Academy of Physician          Joint Injection Workshop                                        5,000.00
 Assistants
 
Letters & Sciences                     Advances in Multiple Sclerosis Research & Practice,            69,000.00
                                        Annual CNE Conference Hosted by Columbia University,
                                        MS Clinical Care and Research Center
 
Mattel Children's Hospital UCLA        Post Doc Fellowship                                            63,000.00
 
Med Learning Group                     Pathologic Targets in Rheumatoid Arthritis: Modifying         288,350.00
                                        the Immune Response to Optimize Patient Outcomes                       Collaboration3
 
Med Learning Group                     A 3-Dimensional View of Recent Advances in                    353,460.00
                                        Personalized Treatment for the Management of                           Collaboration \3\
                                        Uncontrolled Asthma
 
Med-IQ, LLC                            Clinical and Translational Insights in Pompe Disease:         189,407.00
                                        Disease Pathology, Patient Identification, and
                                        Treatment
 
Medscape LLC                           CME LIVE: A Late-Breaking Update on PCSK9 Inhibitors          500,000.00
                                        and Cardiovascular Outcomes                                            Collaboration \3\
 
Medscape LLC                           Advances in Rheumatoid Arthritis 2017: What's the              99,500.00
                                        Conference Buzz?                                                       Collaboration \3\
 
MedStar Georgetown University          4th Annual Current Issues in the Care of Dialysis and          10,000.00
 Hospital                               Transplant Patients
 
Montefiore Medical Center MRCME, LLC   PCSK9 Inhibitor Therapy for Dyslipidemia: Implications        399,845.00
                                        of Outcome Trial Results and a Look to the Future                      Collaboration\3\
 
MS Views and News                      The 2017 Multiple Sclerosis Symposium of South Florida-        20,000.00
                                         The Neurological Aspects of MS and Beyond                             Collaboration \3\
 
National Association for Continuing    Utilizing Concentrated Insulins: A New Strategy for           260,000.00
 Education                              the Insulin Resistant Patient
 
National Association of Managed Care   New Targets in the Therapeutic Landscape for Moderate-         57,000.00
 Physicians, Inc.                       to-Severe Atopic Dermatitis (AD): What Does Managed                    Collaboration \3\
                                        Care Need to Know?
 
National Gaucher Foundation, Inc.      Medical Diagnostic/Testing Program                            150,000.00
                                                                                                               Collaboration \3\
 
National Multiple Sclerosis Society    Life-Changing Breakthroughs: African American                  10,000.00
                                        Education Conference
 
National Organization for Rare         NORD Continuing Medical Education                              80,000.00
 Disorders University of
 Massachusetts Medical School
 
Oregon Health & Science University     17th Annual Pacific Northwest Prostate Cancer                  20,000.00
                                        Conference
 
Penn State College of Medicine MCM     Contemporary Management of Type 2 Diabetes                    166,694.00
 Education
 
Penn State College of Medicine PVI     PeerView In Session, ``Analyzing the Latest Evidence          151,480.00
 Peerview Institute for Medical         in Atopic Dermatitis: Clinical Updates From Geneva''                   Collaboration \3\
 Education Inc.
 
Pennsylvania Society of Physician      ``Joint Injections''                                            5,500.00
 Assistants                                                                                                    Collaboration \3\
 
Pharmacy Times Continuing Education    Advances in Insulin and Insulin Combination Therapies:         68,300.00
                                        Opportunities for Convenient Care Providers to
                                        Improve Patient Outcomes
 
PlatformQ Health Education, LLC        From Novice to Expert: A Series in Multiple Sclerosis         100,000.00
 Consortium of Multiple Sclerosis       Management
 Centers Nurse Practitioner
 Alternatives
 
Postgraduate Healthcare Education,     Understanding the Mechanisms of DMARD Therapy in               53,500.00
 LLC Postgraduate Institute for         Patients with Rheumatoid Arthritis                                     Collaboration \3\
 Medicine
 
Postgraduate Institute for Medicine    The Importance of Early Diagnosis and Timely Access to        349,850.00
 Global Academy for Medical Education   Treatment of RA                                                        Collaboration \3\
 
Postgraduate Institute for Medicine    Defining Personalized Care Plans in Metastatic                 60,000.00
 i3 Health                              Castration-Resistant Prostate Cancer
 
Postgraduate Institute for Medicine    Managing Multiple Sclerosis: Current Treatment and            150,000.00
 Impact Education, LLC                  Care Management Strategies for Managed Care
 
PRIME Education, LLC                   Scaling-Up Shared Decision-Making in Multiple                 162,382.50
                                        Sclerosis Treatment
 
Projects in Knowledge                  The Art & Science of Multiple Sclerosis Management            175,000.00
 
Projects in Knowledge @Point of Care   Atopic Dermatitis @Point of Care                              200,000.00
                                                                                                               Collaboration \3\
 
Regents of the University of Michigan  Pompe Disease Patient Educational Booklet                       2,777.00
                                                                                                               Collaboration \3\
 
Regents University of California Los   Educational Seminars for Patients, Families, and               20,000.00
 Angeles                                Friends 2017-2018
 
Research To Practice                   Year in Review--A Four-Part Multi-tumor Regional CME           40,000.00
                                        Symposia Series Focused on the Application of
                                        Emerging Research Information to the Care of Patients
                                        with Common Cancers: Genitourinary Cancers Module
 
Rheumatology Nurses Society            RNS 2017 Annual Conference                                     25,000.00
                                                                                                               Collaboration \3\
 
RMEI Postgraduate Institute for        Achieving Success in RA Assessment and Management: A          349,547.00
 Medicine                               Learner Pathway to Improve Patient Outcomes                            Collaboration \3\
 
Suffolk Academy of Medicine Long       The Long Island Allergy & Asthma Society 24th Annual           10,000.00
 Island Allergy & Asthma Society        Scientific Meeting                                                     Collaboration \3\
 
Suffolk Academy of Medicine Long       The Long Island Allergy & Asthma Society 24th Annual           10,000.00
 Island Allergy & Asthma Society        Scientific Meeting                                                     Collaboration3
 
The Regents of UC/Office of Cont Med   UCLA Review of Clinical Neurology                               2,500.00
 Educ
 
Tufts University School of Medicine    Severe Asthma: Inspiring Change                               216,712.50
 DKBmed                                                                                                        Collaboration \3\
 
UMA Education, Inc. dba Global         Closing the Gap Created by Clinical Inertia: New              207,845.00
 Education Group Tarsus Cardio Inc.     Strategies for T2DM Treatment
 dba Cardiometabolic Health Congress
 
Universitatsmedizin Rostock, Albrecht- Recent advances in rare diseases: Gaucher disease as a         25,000.00
 Kossel-Institute for                   model (RARD 2017)
 Neuroregeneration (AKos)
 
University of Louisville Research      10th Annual Perspectives in Rheumatic Diseases                 12,500.00
 Foundation Global Academy for          presented by Rheumatology News, Internal Medicine                      Collaboration \3\
 Medical Education, LLC Postgraduate    News & Family Practice News
 Institute for Medicine
 
University of Nevada, Reno School of   2017 Fall Clinical Dermatology Conference                     125,000.00
 Medicine Foundation for Research and
 Education in Dermatology
 
Vindico Medical Education, LLC         When Severe Asthma is Out of Control: Examining               137,340.00
                                        Phenotypic Approaches to Treatment                                     Collaboration \3\
 
Yale New Haven Hospital                New and Emerging Multiple Sclerosis Therapies                  15,000.00
 
Yale School of Medicine                The Yale-Cambridge Transplantation Symposium: Donor            20,000.00
                                        Decision-Making in an Era of Advanced Medical
                                        Complexity
 
----------------------------------------------------------------------------------------------------------------
\1\ Applicant names are provided by the requestor. If applicants apply as a group for a single educational
  activity; all applicants may be not be identified above. The Company funds other educational activities
  (including fellowships and non-physician and patient education); all of which do not appear on this report,
  but appear on other reports on this site.
\2\ ``Funding Amount'' is the amount that the Company funded during Q3, 2017 identified above based upon an
  agreement. Recipients are required to return any unused funds. Information on unused funds returned by the
  applicant on activities are not reported. ``Funding Amount'' does not include funds that may have been
  provided by other affiliated Sanofi Company Entities (e.g., Sanofi Pasteur).
\3\ Collaboration (Shared) Funding--is the full amount of a grant funded under an agreement with Regeneron, some
  or all of which may be shared between the collaborating entities.


                                      Independent Medical Education Grants
                                           1st Oct 2017-31th Dec 2017
    Sanofi US and its affiliate Genzyme Corporation are committed to supporting independent medical education
  activities in therapeutic areas in which the Company is involved, for healthcare professionals, patients, and
   consumers to improve patient care and health outcomes in therapeutic areas in which the Company is engaged.
        Sanofi US and Genzyme Corporation are part of the Sanofi Group, a global pharmaceutical company.
----------------------------------------------------------------------------------------------------------------
                                                                                                 Funding Amount
        Recipient Name(s) \1\                              Activity Title                           ($) \2\
----------------------------------------------------------------------------------------------------------------
AcademicCME, LLC.                      Applying Individualized Therapeutic Strategies of              98,000.00
                                        Switching and Sequencing to Improve Outcomes for
                                        Patients with Multiple Sclerosis: The Right Treatment
                                        at the Right Time for the Right Patient
 
Albert Einstein College of Medicine/   Atopic Dermatitis (Eczema) Challenges: Recognition and        108,682.50
 Montefiore Medical Center M2           Assessment in Primary Care                                             Collaboration \3\
 Communications
 
American Association of Clinical       New Jersey-AACE January Dinner Program: Treatment of            2,591.00
 Endocrinologists                       Advanced Thyroid Cancer
 
American Association of Clinical       Minnesota/Midwest Chapter of the American Association           5,000.00
 Endocrinologists                       of Clinical Endocrinologists 8th Annual Meeting
 
American College of Allergy, Asthma &  Biologics in Atopic Dermatitis Workshop                        25,320.00
 Immunology
 
American College of Allergy, Asthma &  WSAAI 2018: 56th Annual Scientific Session                     20,000.00
 Immunology Western Society of                                                                                 Collaboration \3\
 Allergy, Asthma & Immunology
 
Annenberg Center for Health Sciences   10th Annual Linda Morgante MS Nurse Leadership Program         35,000.00
 at Eisenhower Academy for Continued
 Healthcare Learning (ACHL)
 
Association pulmonaire du Quebec       Biennale de l'Espace francophone de la pneumologie             12,150.00
 
Boston University School of Medicine   Management of Knee Osteoarthritis in Primary Care: The        200,000.00
 Practicing Clinicians Exchange         Case for Viscosupplementation
 Continuing Education Alliance LLC
 
California Optometric Association      2017 Monterey Symposium                                        10,400.00
 
Cedars-Sinai Medical Center            7th Annual Symposium on Lysosomal Storage Disorders            15,000.00
 
Children's Hospital of Philadelphia    Lysosomal Storage Disease (LSD) Fellowship                     75,000.00
 Foundation
 
Cleveland Clinic--Lou Ruvo Center for  Advancing Therapeutics for Multiple Sclerosis                   5,000.00
 Brain Health
 
Cleveland Clinic Center for            Clinical Updates on Fabry Disease: Diagnosis Through          159,750.00
 Continuing Medical Education           Treatment
 Medscape LLC
 
Cleveland Clinic Educational           Medical Dermatology Therapy Update: Autoimmune                 10,000.00
 Foundation                             Diseases, Chronic Inflammatory and Advanced
                                        Malignancies
 
Cleveland Clinic Educational           6th Annual Basic & Clinical Immunology for the Busy            25,000.00
 Foundation                             Clinician
 
CME Outfitters, LLC                    Peeking Beneath the Surface of Atopic Dermatitis:             200,000.00
                                        Testing Your Skills from Pathogenesis to Treatment
 
Division of Medical Genetics and       Better Outcomes of Lysosomal Diseases (BOLD)                   75,000.00
 Genomic Medicine                       Fellowship
 
Elsevier Office of Continuing Medical  THE LSD DEBATE: OPTIMIZING DIAGNOSIS AND FUTURE               248,465.00
 Education Excerpta Medica BV           MANAGEMENT
 
Elsevier Office of Continuing Medical  Clinical Issues in Severe Asthma: Debates and                 628,867.00
 Education Integritas Communications    Discussions About Personalizing Patient Management
 
Elsevier Office of Continuing Medical  Clinical Issues in Atopic Dermatitis: Discussions and         784,641.50
 Education Integritas Communications    Debates on Managing Moderate-to-Severe Disease                         Collaboration \3\
 
Emory University                       The Paul M. Fernhoff Genetic Counseling Fellowship in          75,000.00
                                        the Lysosomal Storage and Other Genetic Disorders
 
EUFOREA IVZW                           European Rhinology Research Forum                              18,000.00
 
European Respiratory Society           ERS Satellites                                                 72,000.00
 
European Society for Dermatological    47th ESDR Meeting 2017                                         44,400.00
 Research
 
Excel Continuing Education             Responding to the Challenge of Pompe Disease                  100,165.00
                                        (satellite symposium at 2018 World Congress)
 
George Washington University (GW)      American Contact Dermatitis Society-Frontiers in               10,000.00
 Office of Continuing Education in      Dermatitis 2017                                                        Collaboration \3\
 the Health Profession (CEHP)
 American Contact Dermatitis Society
 
Global Education Group Integritas      Clinical Issues in Atopic Dermatitis: Discussions and         177,074.00
 Communications                         Debates on Managing Moderate-to-Severe Disease                         Collaboration \3\
 
Icahn School of Medicine at Mount      4th NY Masters Course in Endocrinology and Endocrine           10,000.00
 Sinai                                  Surgery                                                                Collaboration \3\
 
Icahn School of Medicine at Mount      20th Annual Mount Sinai Winter Symposium ``Advances in         20,000.00
 Sinai                                  Medical & Surgical Dermatology''
 
Indiana Academy of Physician           ``Anterior Knee Pain and Osteoarthritis''                       5,000.00
 Assistants
 
Institute for Medical and Nursing      MEDS 2018: Going Flat-Out for Glycemic Control: The           381,055.00
 Education, Inc.                        Role of New Basal Insulins in Patient-Centered T2DM
                                        Management
 
Institute for Medical and Nursing      MEDS 2018: Rationale, Recognition, and                        354,830.00
 Education, Inc.                        Recommendations: Expert Perspectives on Combining
                                        Basal Insulin and GLP-1 RAs to Intensify Treatment of
                                        T2DM
 
Kidney Disease Improving Global        KDIGO Controversies Conference on Glomerular Diseases          25,000.00
 Outcomes (KDIGO)
 
Med Learning Group                     Recognizing the Connection: A View into the Parallels         225,000.00
                                        between Asthma and Nasal Polyps
 
Medical Education Resources, Inc.      Basic concepts in eczema diagnosis and management              20,000.00
 Dermveda Inc.
 
Medical Learning Institute Inc. PVI,   PeerView ``Ascertaining the Potential Clinical                 80,000.00
 Peerview Institute for Medical         Implications of The Latest Data on Approved and
 Education Inc.                         Emerging Disease Modifying Therapies for Multiple
                                        Sclerosis Management: A Recap from Paris''
 
Medical Learning Institute Inc. PVI,   PeerView in Session, ``Exploring the Latest Data in            74,490.00
 PeerView Institute for Medical         the Treatment of Uncontrolled Persistent Asthma:                       Collaboration \3\
 Education, Inc.                        Clinical Highlights from San Diego''
 
Medical Learning Institute PVI,        PeerView Talks, ``A Patient-Centered Approach to the          153,580.00
 PeerView Institute for Medical         Diagnosis and Treatment of Atopic Dermatitis in                        Collaboration \3\
 Education                              Adults: An Expert's Story''
 
Med-IQ, LLC                            Pragmatic Approaches to Improving Insulin Introduction        254,623.00
                                        and Integration in T2DM:Patient Simulations For
                                        Frontline Providers
 
Med-IQ, LLC                            Addressing Bone Manifestations of GD: The Latest              382,736.00
                                        Evidence in Evaluation and Treatment
 
Medscape LLC                           Updates and Perspectives in Diabetic Dyslipidemia:            246,500.00
                                        2017 in Review                                                         Collaboration \3\
 
Medscape LLC                           Addressing Disease Burden in Asthma and Comorbidities:        400,000.00
                                        From Pathophysiology to Targeted Treatments
 
Medstar Georgetown University          Multiple Sclerosis Patient Education Day                        7,500.00
 Hospital
 
Mount Sinai School of Medicine         The Icahn School of Medicine at Mount Sinai NP                 75,000.00
                                        Fellowship Program in Lysosomal Storage Disease
 
National Association For Continuing    Atopic Dermatitis: New Insights, New Therapies                150,000.00
 Education
 
National Committee for Quality         A Patient-Centered Approach to Severe Asthma                  232,325.00
 Assurance NACCME, LLC                  Management: Embracing Diversity and Improving                          Collaboration \3\
                                        Outcomes with Emerging Therapies
 
NCCN Foundation                        NCCN Guidelines for Patients: Prostate Cancer                  25,000.00
 
Nurse Practitioner Alternatives        Advances In Multiple Sclerosis (AIMS) Primer: Third            59,150.00
 Consortium of Multiple Sclerosis       Edition
 Centers
 
Nurse Practitioner Alternatives        1,800 SecondsTM in MS Management: An Online                    92,000.00
 Consortium of Multiple Sclerosis       Educational Series for MS Clinicians
 Centers
 
Oakstone Publishing, LLC PeerVoice     A New Treatment Paradigm in Atopic Dermatitis: Expert         268,700.00
 America Limited                        Insights on Incorporating Biologic Therapy Among
                                        Available Options
 
Oakstone Publishing, LLC PeerVoice     Optimizing Systemic Therapy for Atopic Dermatitis:            268,700.00
 America Limited                        Practical Strategies to Ensure Patient Safety
 
Oregon Health and Science University   Annual OHSU Colloquium on Neuromuscular Disorders               5,000.00
 
PEERVOICE AMERICA LIMITED Oakstone     ``Practical Strategies for Managing Inadequate                193,250.00
 Publishing, LLC                        Responders to Atopic Dermatitis Treatment''                            Collaboration \3\
 
Penn State College of Medicine         Beyond the Guidelines: Investigator Perspectives on           100,000.00
 Research To Practice                   Current Clinical Issues and Ongoing Research in the
                                        Management of Advanced Prostate Cancer
 
PESG Lysosomal And Rare Disorders      GRIDS2017: A workshop on immune aspects of Lysosomal           55,000.00
 Research And Treatment Center Inc.     Storage Disorders: From pathology to therapy
 
Pharmacy Times Continuing Education    A Specialty Pharmacy Update on PCSK9 Inhibitor Therapy         10,000.00
                                        for Hypercholesterolemia                                               Collaboration \3\
 
Pharmacy Times Continuing Education    An American Journal of Managed Care Webinar:                   75,255.00
                                        Evaluating Novel Therapies for Atopic Dermatitis
 
Physician's Education Resource, LLC    Provider and Caregiver Connection--Getting Beneath the        167,850.00
                                        Surface: Addressing Patient Concerns In Moderate to
                                        Severe Atopic Dermatitis
 
Postgraduate Institute for Medicine    Early Detection and New Approaches to the Management          150,000.00
 Catamount Medical Education, LLC       of Atopic Dermatitis in the Family Medicine Setting                    Collaboration3
 
Postgraduate Institute for Medicine    The Role of Specialty Pharmacy and the Challenge of           150,000.00
 Impact Education, LLC                  Managing Moderate-to-Severe Atopic Dermatitis                          Collaboration \3\
 
Postgraduate Institute for Medicine    The Management of Atopic Dermatitis: Entering a New           200,000.00
 Impact Education, LLC                  Paradigm
 
Postgraduate Institute for Medicine    Rheumatoid Arthritis Management Strategies: New               150,000.00
 Impact Education, LLC                  Insights for Managed Care
 
Postgraduate Institute for Medicine    The Learning Pathway in Atopic Dermatitis: Optimizing         382,947.00
 Robert Michael Educational Institute   Management Approaches in Patients with Moderate-to-                    Collaboration \3\
 LLC                                    Severe Disease
 
Potomac Center for Medical Education   Targeting Improved Outcomes In Atopic Dermatitis:             449,955.00
 Rockpointe Corporation                 Strategies for Achieving Personalized Treatment Goals                  Collaboration \3\
 
Potomac Center for Medical Education   Achieving New Treatment Goals In Multiple Sclerosis:          176,000.00
 Rockpointe Corporation Nurse           Strategies for Initial Treatment Selection and
 Practitioner Alternatives              Patient Engagement
 
PRIME Education, LLC                   Aligning Managed Care Decision-Making with the Latest         272,543.00
                                        Evidence for Targeted Asthma Treatment
 
PRIME Education, LLC                   Navigating the Intersection of Uncontrolled Asthma and        354,188.00
                                        Related Comorbidities: Implications of Novel
                                        Mechanisms of Action for Managed Care
 
PRIME Education, LLC                   Advancing Specialty Pharmacy Decision-Making to               242,011.00
                                        Optimize Therapy Selection and Access in Uncontrolled
                                        and Severe Asthma
 
PRIME Education, LLC                   Solving the Problem of Choice in Treatment Decisions          182,535.00
                                        for Patients with Rheumatoid Arthritis: Evidence-
                                        Based, Guideline-Directed, and Patient-Centered
                                        Strategies
 
Pri-Med Institute, LLC                 Viscosupplementation for Osteoarthritis of the Knee:          149,499.92
                                        Who, When, and How?
 
Projects In Knowledge                  Asthma--Practical Applications from ATS 2018: A Video          50,000.00
                                        Roundtable
 
Rutgers, The State University of New   Cognitive Dysfunction and Fatigue in Multiple                   3,011.00
 Jersey                                 Sclerosis
 
Sidney Kimmel Medical College at       Thyroid Cancer 2017: New Advances in Diagnosis &               10,000.00
 Thomas Jefferson                       Treatment
 
Society for Inherited Metabolic        2017 North American Metabolic Academy                          20,000.00
 Disorders
 
St. Joseph's Regional Medical Center   Multiple Sclerosis: A Changing Landscape                        1,300.00
 
The France Foundation                  Achieving Better Control of Severe Asthma: New                262,700.00
                                        Understandings in Asthma Pathophysiology and Targeted
                                        Therapies
 
The France Foundation                  Are You Ready? Recent Effective Atopic Dermatitis             240,720.00
                                        Therapy Considerations
 
The Regents of the University of       Post Doc Fellowship                                            63,000.00
 California--UCLA Division of
 Nephrology
 
UC Regents                             Genetic Neuromuscular Diseases Fellowship                      75,000.00
 
UMA Education, Inc. dba Global         Beyond the Flare: A Practical Overview of the Newest           25,000.00
 Education Group Tarsus Cardio dba      Concepts in Atopic Dermatitis Pathogenesis and                         Collaboration \3\
 South Beach Symposium                  Treatment
 
UMA Education, Inc. dba Global         2018 Masters of Pediatric Dermatology Symposium                20,000.00
 Education Group Tarsus Cardio Inc.,                                                                           Collaboration \3\
 dba South Beach Symposium
 
University Neurology, Inc.             The 2017 New York State Multiple Sclerosis Consortium           5,000.00
                                        (NYSMSC) Annual Professional Research and Education
                                        Meeting
 
University of Alabama at Birmingham    2017 Fabry Fellowship                                          73,714.12
 
University of California, San Diego    Challenges in Pompe                                             4,800.00
 San Diego Neurology Society
 
University of Colorado School of       87th Annual Meeting of the American Thyroid                    50,000.00
 Medicine American Thyroid              Association
 Association
 
University of Louisville School of     Visiting Professor and Endocrine Grand Rounds                   3,320.00
 Medicine
 
University of Louisville Global        Skin Disease Education Foundation's 18th Annual Las            25,000.00
 Academy for Medical Education          Vegas Dermatology Seminar featuring the 14th Annual                    Collaboration \3\
 Postgraduate Institute for Medicine    Psoriasis Forum
 
University of Louisville Postgraduate  17th Annual Caribbean Dermatology Symposium                    50,000.00
 Institute of Medicine Global Academy                                                                          Collaboration \3\
 for Medical Education
 
University of Louisville Postgraduate  Skin Disease Education Foundation's 42nd Annual Hawaii         50,000.00
 Institute of Medicine Global Academy   Dermatology Seminar                                                    Collaboration \3\
 for Medical Education
 
University of Massachusetts Medical    New Frontiers and Pivotal Investigation-Based Advances        369,000.00
 School CMEducation Resources           in the Pathoimmunobiology and Management of Atopic                     Collaboration \3\
                                        Dermatitis
 
Vindico Medical Education, LLC         Shutting Down MS: New Insights on Induction,                  196,378.58
                                        Escalation, Oral Agents, and Monitoring
 
WEBMD Global                           Advancing the Care of Patients With Atopic Dermatitis-        301,000.00
                                        International Perspectives for OUS MDS: An Initiative
                                        developed in partnership with the University of
                                        Sheffield Medical School, Dermatology Research
 
----------------------------------------------------------------------------------------------------------------
\1\ Applicant names are provided by the requestor. If applicants apply as a group for a single educational
  activity; all applicants may be not be identified above. The Company funds other educational activities
  (including fellowships and non-physician and patient education); all of which do not appear on this report,
  but appear on other reports on this site.
\2\ ``Funding Amount'' is the amount that the Company funded during Q4, 2017 identified above based upon an
  agreement. Recipients are required to return any unused funds. Information on unused funds returned by the
  applicant on activities are not reported. ``Funding Amount'' does not include funds that may have been
  provided by other affiliated Sanofi Company Entities (e.g., Sanofi Pasteur).
\3\ Collaboration (Shared) Funding--is the full amount of a grant funded under an agreement with Regeneron, some
  or all of which may be shared between the collaborating entities.


 
                  Organization Name                          Amount
 
Acid Maltase Deficiency Association INC.                       $5,000.00
 
Allergy & Asthma Network Mothers of Asthmatics, INC           $50,000.00
 
Allergy & Asthma Network Mothers of Asthmatics, INC.         $117,000.00
 
Allergy & Asthma Network Mothers of Asthmatics, INC.          $25,000.00
 
Allergy & Asthma Network Mothers of Asthmatics, INC.          $25,000.00
 
Allergy & Asthma Network Mothers of Asthmatics, INC.          $25,000.00
 
Allergy & Asthma Network Mothers of Asthmatics, INC.          $25,000.00
 
Allergy & Asthma Network Mothers of Asthmatics, INC.          $60,000.00
 
Allergy & Asthma Network Mothers of Asthmatics, INC.          $75,000.00
 
Alliance for the Adoption of Innovations in Medicine          $50,000.00
 
American Association Of Kidney Patients Inc.                 $362,293.31
 
American Association Of Kidney Patients Inc.                  $10,000.00
 
American College of Allergy, Asthma & Immunology               $6,000.00
 
American College of Allergy, Asthma & Immunology              $30,000.00
 
American College of Allergy, Asthma & Immunology              $70,000.00
 
American College of Allergy, Asthma & Immunology             $100,000.00
 
American College of Allergy, Asthma & Immunology              $60,000.00
 
American College of Allergy, Asthma & Immunology              $55,000.00
 
American College of Allergy, Asthma & Immunology              $95,000.00
 
American College of Allergy, Asthma & Immunology             $165,000.00
 
American College of Allergy, Asthma & Immunology              $35,000.00
 
American College of Allergy, Asthma & Immunology              $30,000.00
 
American College of Allergy, Asthma & Immunology             $150,000.00
 
American College of Allergy, Asthma & Immunology             $175,000.00
 
American Kidney Fund Inc.                                     $40,000.00
 
American Kidney Fund Inc.                                     $10,000.00
 
APFED (American Partnership for Eosinophilic                  $15,000.00
 Disorders)
 
Arthritis Foundation                                         $100,000.00
 
Arthritis Foundation                                          $25,000.00
 
Arthritis Foundation                                          $25,000.00
 
Arthritis Foundation                                           $3,500.00
 
Arthritis Foundation                                           $1,250.00
 
Arthritis Foundation                                           $5,000.00
 
Arthritis Foundation                                          $10,000.00
 
Arthritis Foundation                                           $3,500.00
 
Arthritis Foundation                                         $250,000.00
 
Arthritis Foundation                                         $250,000.00
 
Arthritis Foundation                                          $30,000.00
 
Arthritis Foundation                                         $100,000.00
 
Arthritis Foundation                                         $100,000.00
 
Arthritis Foundation Inc.                                      $2,500.00
 
Arthritis Foundation of NENY                                   $5,000.00
 
Association For Glycogen Storage Disease                       $3,000.00
 
Asthma and Allergy Foundation of America                     $150,000.00
 
Asthma and Allergy Foundation of America                      $24,200.00
 
Asthma and Allergy Foundation of America                      $50,000.00
 
Asthma and Allergy Foundation of America                      $75,000.00
 
Asthma and Allergy Foundation of America                     $100,000.00
 
Asthma and Allergy Foundation of America, New England         $20,000.00
 Chapter
 
Aubrey Rose Foundation                                        $25,000.00
 
Barbara Ann Karmanos Cancer Institute                         $10,000.00
 
Be The Match Foundation                                       $40,000.00
 
Berkshire Resource Project                                     $1,500.00
 
Berkshire Resource Project                                     $1,500.00
 
Beyond the Diagnosis                                          $10,000.00
 
Can Do Multiple Sclerosis                                      $8,000.00
 
Can Do Multiple Sclerosis                                     $40,000.00
 
Can Do Multiple Sclerosis                                     $26,000.00
 
Can Do Multiple Sclerosis                                     $10,000.00
 
Can Do Multiple Sclerosis                                     $10,000.00
 
Can Do Multiple Sclerosis                                     $20,000.00
 
Can Do Multiple Sclerosis                                     $20,000.00
 
Can Do Multiple Sclerosis                                     $30,000.00
 
Can Do Multiple Sclerosis                                     $40,000.00
 
Can Do Multiple Sclerosis                                     $70,000.00
 
Can Do Multiple Sclerosis                                     $30,000.00
 
Community Oncology Alliance                                   $75,000.00
 
CrowdCare Foundation                                          $45,000.00
 
Cure GM1 Incorporated                                          $5,000.00
 
Cure GM1 Incorporated                                          $5,000.00
 
Cystic Fibrosis Foundation                                    $10,000.00
 
EveryLife Foundation for Rare Diseases                        $10,000.00
 
EveryLife Foundation for Rare Diseases                        $30,000.00
 
EveryLife Foundation for Rare Diseases                         $5,000.00
 
EveryLife Foundation for Rare Diseases                        $30,000.00
 
EveryLife Foundation for Rare Diseases                        $15,000.00
 
EveryLife Foundation for Rare Diseases                        $25,000.00
 
EveryLife Foundation for Rare Diseases                        $20,000.00
 
Fabry Support & Information Group                             $22,000.00
 
Fabry Support & Information Group                              $1,500.00
 
Fabry Support & Information Group                             $50,000.00
 
Fabry Support & Information Group                             $30,000.00
 
Fabry Support & Information Group                            $100,000.00
 
Florida Hemophilia Association                                 $3,000.00
 
Foundation Fighting Blindness Inc.                             $5,000.00
 
Fundacion de Esclerosis Multiple de Puerto Rico               $15,000.00
 
Global Alliance for Patient Access                           $115,000.00
 
Global Alliance for Patient Access                            $30,000.00
 
Global Healthy Living Foundation, Inc.                       $100,000.00
 
Global Healthy Living Foundation, Inc.                        $50,000.00
 
Global Parents for Eczema Research, a project of              $47,438.00
 Heluna Health
 
Great Lakes Hemophilia Foundation Inc.                         $2,500.00
 
Hemophilia Foundation of Northern California                   $5,000.00
 
Hemophilia of Iowa                                             $1,500.00
 
Hemophilia of Iowa                                             $1,000.00
 
Hemophilia of North Carolina                                   $5,000.00
 
Hermansky-Pudlak Syndrome Network                             $24,935.00
 
Holy Name Health Care MS Center                                $2,500.00
 
Holy Name Health Care MS Center                                $2,500.00
 
Hope for Hemophilia                                           $15,000.00
 
Hope for Hemophilia                                           $15,000.00
 
International Myeloma Foundation                              $75,000.00
 
International Myeloma Foundation                              $50,000.00
 
International Myeloma Foundation                              $75,000.00
 
International Society For Mannosidosis & Related              $30,000.00
 Disease Inc.
 
Kessler Foundation                                             $5,000.00
 
Leukemia & Lymphoma Society--MA Chapter                       $20,000.00
 
Light of Life Foundation                                       $5,000.00
 
Little Miss Hannah Foundation                                  $1,000.00
 
Lone Star Chapter of the National Hemophilia                  $15,000.00
 Foundation
 
Lymphoma Research Foundation                                  $20,000.00
 
March of Dimes Foundation                                     $10,000.00
 
March of Dimes Foundation                                     $15,000.00
 
Mercy Foundation                                              $20,000.00
 
Mid America MS Achievement Center                              $5,000.00
 
Mid America MS Achievement Center                              $5,000.00
 
MLD Foundation                                                $12,000.00
 
MLD Foundation                                                $12,000.00
 
MS Bright Spots of Hope                                        $2,500.00
 
MS Cure Fund                                                   $3,000.00
 
MS Cure Fund                                                   $5,250.00
 
MS Cure Fund                                                   $2,500.00
 
MS Dream Center--RI, Inc.                                      $3,000.00
 
MS HOPE FOR A CURE INC.                                       $10,000.00
 
MS Views and News                                             $25,000.00
 
MS Views and News                                             $50,000.00
 
MS Views and News                                             $30,000.00
 
MS Views and News                                             $30,000.00
 
MS Views and News                                             $10,000.00
 
MS Views and News                                             $40,000.00
 
MS Views and News                                             $25,000.00
 
MSWorld, Inc.                                                  $4,000.00
 
Multiple Myeloma Cure Seeker Society                           $5,000.00
 
Multiple Sclerosis Association of America                    $200,000.00
 
Multiple Sclerosis Association of America                     $30,000.00
 
Multiple Sclerosis Association of America                     $25,000.00
 
Multiple Sclerosis Association of America                     $50,000.00
 
Multiple Sclerosis Association of America                     $50,000.00
 
Multiple Sclerosis Association of America                     $46,031.00
 
Multiple Sclerosis Center of Georgia                          $10,000.00
 
Multiple Sclerosis Center of Georgia                           $7,000.00
 
Multiple Sclerosis Foundation                                 $30,000.00
 
Multiple Sclerosis Foundation                                 $20,000.00
 
Multiple Sclerosis Foundation                                 $50,000.00
 
Multiple Sclerosis Resources of Central New York, Inc.         $7,500.00
 
Muscular Dystrophy Association                                $20,000.00
 
Muscular Dystrophy Association                               $430,000.00
 
National Bone Marrow Transplant Link                           $3,000.00
 
National Eczema Association                                  $100,000.00
 
National Eczema Association                                   $85,000.00
 
National Eczema Association                                  $100,000.00
 
National Eczema Association                                   $75,000.00
 
National Eczema Association                                  $100,000.00
 
National Fabry Disease Foundation                            $100,000.00
 
National Fabry Disease Foundation                            $100,000.00
 
National Fabry Disease Foundation                             $40,000.00
 
National Gaucher Foundation                                $1,500,000.00
 
National Gaucher Foundation                                  $650,000.00
 
National Gaucher Foundation                                  $200,000.00
 
National Gaucher Foundation                                $1,900,000.00
 
National Hemophilia Foundation                                $37,500.00
 
National Hemophilia Foundation                               $100,000.00
 
National Hemophilia Foundation                                 $9,479.00
 
National Kidney Foundation                                     $3,700.00
 
National Kidney Foundation                                    $10,000.00
 
National Kidney Foundation                                    $10,000.00
 
National MPS Society                                             $500.00
 
National MPS Society                                          $20,000.00
 
National MPS Society                                         $100,000.00
 
National MS Society                                            $5,000.00
 
National Multiple Sclerosis Society                          $780,000.00
 
National Multiple Sclerosis Society                           $65,000.00
 
National Multiple Sclerosis Society                           $15,000.00
 
National Multiple Sclerosis Society                            $2,500.00
 
National Multiple Sclerosis Society                           $15,000.00
 
National Multiple Sclerosis Society                          $750,000.00
 
National Multiple Sclerosis Society                          $150,000.00
 
National Multiple Sclerosis Society New York City              $2,500.00
 Chapter
 
National Multiple Sclerosis Society New York City              $1,100.00
 Chapter
 
National Multiple Sclerosis Society New York City             $15,000.00
 Chapter
 
National Multiple Sclerosis Society New York City            $122,100.00
 Chapter
 
National Multiple Sclerosis Society New York City              $5,000.00
 Chapter
 
National Multiple Sclerosis Society New York City              $1,250.00
 Chapter
 
National Multiple Sclerosis Society New York City                $300.00
 Chapter
 
National Multiple Sclerosis Society New York City              $1,000.00
 Chapter
 
National Multiple Sclerosis Society New York City              $5,000.00
 Chapter
 
National Multiple Sclerosis Society New York City              $5,000.00
 Chapter
 
National Niemann-Pick Disease Foundation                      $40,000.00
 
National Organization for Rare Disorders, Inc.                $50,000.00
 
National Organization for Rare Disorders, Inc.                 $5,000.00
 
National Organization for Rare Disorders, Inc.                $25,000.00
 
National Organization for Rare Disorders, Inc.               $100,000.00
 
National Organization for Rare Disorders, Inc.                $75,000.00
 
National Organization for Rare Disorders, Inc.                $50,000.00
 
National Tay-Sachs & Allied Diseases Association, Inc.        $20,000.00
 
National Tay-Sachs & Allied Diseases Association, Inc.        $10,000.00
 
National Tay-Sachs & Allied Diseases Association, Inc.        $10,000.00
 
New England Hemophilia Association                             $5,000.00
 
New England Hemophilia Association                            $10,000.00
 
New England Hemophilia Association                             $2,500.00
 
New England Hemophilia Association                             $7,500.00
 
Next Step Fund Inc.                                           $10,000.00
 
OhioHealth Corporation                                        $25,000.00
 
Osteogenesis Imperfecta Foundation                             $5,000.00
 
Patient Access Network Foundation                            $300,000.00
 
Patient Empowerment Network                                   $20,000.00
 
Patient Empowerment Network                                   $20,000.00
 
Patient Services, Inc.                                       $662,500.00
 
Patient Services, Inc.                                     $2,381,250.00
 
Patient Services, Inc.                                     $4,797,500.00
 
Patient Services, Inc.                                     $1,418,750.00
 
Patient Services, Inc.                                     $1,365,000.00
 
PKD Foundation                                                $50,000.00
 
PKD Foundation                                                $20,000.00
 
PKD Foundation                                                $25,000.00
 
Prostate Cancer Foundation                                   $300,000.00
 
Prostate Health Education Network Inc.                        $20,000.00
 
Quinn Madeleine Inc.                                           $5,000.00
 
Rare Disease United Foundation                                $15,000.00
 
Rare New England, INC.                                         $4,000.00
 
Rare New England, INC.                                         $4,000.00
 
Rare New England, INC.                                         $4,000.00
 
Rocky Mountain Multiple Sclerosis Center                       $2,500.00
 
Rocky Mountain Multiple Sclerosis Center                       $5,000.00
 
Rocky Mountain Multiple Sclerosis Center                       $5,000.00
 
Rocky Mountain Multiple Sclerosis Center                       $2,500.00
 
Rocky Mountain Multiple Sclerosis Center                       $3,000.00
 
Sofia Sees Hope                                               $22,000.00
 
Swiss Hemophilia Society (Schweizerische Hemophilie            $2,600.00
 Gesellschaft)
 
The Assistance Fund, Inc.                                 $10,000,000.00
 
The Leukemia & Lymphoma Society Eastern PA Chapter            $10,000.00
 
ThyCa: Thyroid Cancer Survivors' Association, Inc.             $5,000.00
 
ThyCa: Thyroid Cancer Survivors' Association, Inc.             $3,000.00
 
ThyCa: Thyroid Cancer Survivors' Association, Inc.             $5,000.00
 
ThyCa: Thyroid Cancer Survivors' Association, Inc.            $10,000.00
 
Tisch Multiple Sclerosis Research Center of New York,         $15,000.00
 Inc.
 
Tisch Multiple Sclerosis Research Center of New York,          $2,500.00
 Inc.
 
Transplant Life Foundation                                    $12,000.00
 
Tri-State Multiple Sclerosis Association                       $2,500.00
 
United Pompe Foundation                                       $50,000.00
 
United Pompe Foundation                                       $42,500.00
 
United Pompe Foundation                                       $30,000.00
 
United States Bone and Joint Initiative, NFP                  $80,000.00
 
United States Bone and Joint Initiative, NFP                  $30,000.00
 
United States Bone and Joint Initiative, NFP                  $25,000.00
 
University of Minnesota Foundation                             $5,000.00
 
Us TOO International                                           $2,500.00
 
Us TOO International                                          $30,000.00
 
Wylder Nation Foundation                                       $5,000.00
 
Wylder Nation Foundation                                      $15,000.00
 


                              Program/Event
 
 
 
PCMA of Texas's Pull     Telehealth 2018          Patient Awareness
 for Pompe                                         Program
 
Understanding Severe     2018 USAsthma Summit     Corporate Council 2018
 Asthma Program
 
2018 Allergy & Asthma    2018 Asthma Bloggers     Understanding Severe
 Awareness Day            Conference               Asthma Guide
 
Webinars on              Medical Education        Education Project
 Dermatological
 Conditions in the
 Workplace
 
Eczema Online Program    Patient Awareness        Patient Awareness
                          Program                  Program
 
Fellow-in-Training       Severe Atopic            2018 Corporate Council
 Travel Scholarships      Dermatitis Toolkit       Membership
                          Program
 
Biologics Education      Severe Asthma Allergist  Webinar Education
 Program                  and Patient Education    Program
 
Severe Asthma Patient    Practice Management      Educational Tools for
 Education                Center: Expansion and    Allergists and
                          Enhancement              Patient Education
                                                   Campaign
 
Patient Education        Proposal Request in      Annual Patient
 Program                  Support of 360 Degrees   Education Conference
                          of Care
 
Patient Voice Access     Arthritis Foundation     2018 Arthritis
 Project                  Patient Engagement at    Foundation Conference
                          ACR                      of Champions
 
2018 Bone Bash           Silver Ball Fundraiser   Evening of Honors
 Fundraiser                                        Fundraiser
 
Freedom of Movement      San Francisco Bone Bash  2018 Jingle Bell Run
 Fundraiser               Fundraiser
 
Walk to Cure Arthritis   Arthritis Industry       Patient Awareness
                          Forum (AIF)              Program
 
Patient Education and    2018 Bone Bash           Albany Commitment to a
 Awareness Program        Fundraiser               Cure Fundraiser
 
Annual GSD Conference    Patient Education        Patient Access Program
                          Program
 
My Life With AD          AAFA's Patient Support   My Kids' Life With
                          Center                   Asthma
 
Be Smart and Breathe     Medical Resources for    8th Annual Prostate
 Easy Patient Education   Children: An             Cancer Symposium
                          Invaluable Database
 
Be The Match 2018        Patient Education and    Patient Education
 National Walk+Run        Awareness Program        Program
 Series
 
Operating Support        Patient Awareness        2019 SKI for MS
                          Program
 
2019 JUMPSTART Program   2018 MS Global Patient   9th Annual Can Do
 Exhibits                 Programs                 Month
 
2018 Young               2018 JUMPSTART Program   2018 Online Programs
 Professionals Program    Exhibition               Sponsorship
 
2018 CAN DO Program      2018 JUMPSTART Program   2018 Can Do On Demand
 
2018 COA Corporate       Patient Awareness        2nd GM1 Research
 Sponsorship              Program                  Symposium
 
TORCH award donation     Fundraiser event         Patient Awareness
                                                   Program
 
RareVoice Awards         Rare Disease Scientific  RARE on the Road
                          Workshop                 Leadership Series
 
Patient Awareness        Rare Disease Week        Community Congress
 Program                  Sponsorship
 
FSIG Patient Meetings    2018 Fun Run/Walk        2018 FSIG Expert Fabry
                                                   Conference
 
Patient Assistance       Operating Support        35th Annual Florida
 Program                                           Bleeding Disorders
                                                   Conference
 
Boston VisionWalk        Managing MS: A           European RA patient
                          multidisciplinary        online program
                          approach
 
European Alliance for    Patient Education and    50-State Network
 Patient Access RA        Awareness Program        Patient Advocacy
 Stakeholders Workshop
 
Assessing and            2018 Wisconsin Bleeding  BLeaders
 Communicating the        Disorders Conference
 Impact of AD on
 Patients and Families
 
Annual Meeting           Teen Program             Family Education
 Sponsorship                                       Program
 
Research Program         2018 MS Awards           21st Annual Spring
                          Reception                Fling for MS
 
Superhero Run/Walk--     2018 Superhero Hope Run/ Long Term Care
 Covington                Walk--Wichita            Survivors Initiative
 
2018 IMF Patient IMF     9th Annual               6th Glycoproteinoses
 Patient and Family       International Myeloma    International
 Seminars and Regional    Working Group Summit     Conference--Atlanta--
 Community Workshops                               USA
 
Kessler Foundation's     Light The Night Boston   Light of Life
 2018 Stroll 'N Roll                               Foundation 2018
 Walk                                              Patient Activities
 
3rd Annual Vegas Cares   Texas Bleeding           Research Program
 About Rare Kids 5K       Disorders Conference
                          2018
 
Fundraising Event        Boston March for Babies  Multiple Sclerosis
                                                   Achievement Center
                                                   Wellness Education
                                                   programs
 
Eat Bid Laugh 7 Program  Race to Nowhere 2018     RUSP Roundtable
                                                   Program
 
RUSP Roundtable Program  MS Bright Spots Evening  6th ANNUAL MS ADAPTIVE
                          of Hope                  SKI DAY--THRIVING
                                                   BEYOND MS!
 
Relapse Management and   MS ALPINE ADVENTURES    Exhibit Sponsorship
 Rehabilitation Program   2018 ADAPTIVE SKI DAY
 
2018 MS Hope Day         Patient Education and    Patient Education and
                          Awareness Program        Awareness Program
 
Patient Education and    Patient Education and    2018 Champions
 Awareness Program        Awareness Program        Tackling MS Awards
                                                   Dinner
 
Patient Education and    Patient Education and    2018 ``MSWorld Talks''
 Awareness Program        Awareness Program        Cleveland Clinic:
                                                   Display Table
 
2018 Defeat Multiple     Patient Assistance       A Better Understanding
 Myeloma Run/Walk         Program                  of MS within the
                                                   Hispanic Community
 
Patient Education and    2018 Multiple Sclerosis  MS Awareness Month
 Awareness Program        Summit: A Community      2018
                          Conference and
                          Exposition
 
2018 Needs Assessment    MS Fest for Patients     Health, Hope & Hops
 
MS Focus' Homecare       MS Focus' Assistive      National MS Education
 Assistance Grant         Technology Program       and Awareness Month
 Program                                           2018
 
2018 Mission Steps Walk  Congress Sponsorship     Community Education
 and MS Awareness Days                             and Engagement
                                                   Support
 
Resource Guide of        Eczema Awareness Month-  The Face of Atopic
 Helpful Organizations    Unhide Eczema Campaign   Dermatitis in America
 
Eczema Expo '18          Atopic Dermatitis Teen   Educational Webcasts
                          Commitment Campaign      for Patients &
                                                   Caregivers
 
Operating Support        2018 Fabry Community     Community support
                          Support and Education    programs
                          programs
 
Patient Assistance       Patient Education and    Patient Education and
 Program                  Awareness Program        Awareness Program
 
Patient Assistance       NHF 2018 Bleeding        UNITE for Bleeding
 Program                  Disorders Conference     Disorders National
                                                   Walk 2018
 
NHF Bleeding Disorders   Congress Sponsorship     New York City Kidney
 Conference 2018                                   Walk
 
The Big Ask The Big      In-Kind Donation         National MPS Society
 Give                                              National Run Program
 
2018--15th               Bike MS: City to Shore   National sponsorship
 International            Ride                     of Walk MS and local
 Symposium on MPS and                              sponsorship of select
 Related Diseases                                  Bike MS events
 
MS Breakthroughs         2018 National MS         Women on the Move--
 Program                  Society Leadership       Pittsburgh
                          Conference
 
Everyday Matters:        National MS Society      Fellowship Program
 Living Your Best Life    National Event
 with MS                  Sponsorship
 
Knoxville Fall Crush     40th Annual Ambassadors  Mood Changes In MS
                          Fundraiser
 
Alliance Industry Forum  On the Move Luncheon--   Women on the Move
 2018                     New Orleans              Luncheon and Fashion
                                                   Show--Cincinnati
 
Women On the Move--      2018 On the Move         On The Move Luncheon-
 Washington, D.C.         Luncheon--St Louis       Houston
 
2017 On The Move         Patient Education and    Patient Assistance
 Luncheon--Dallas TXH     Awareness Program        Program
 
Running for Rare         2018 Corporate Council   Patient Education and
                          Membership--Corporate    Awareness Program
                          Product Member
 
2018 Rare Diseases and   2018 Rare Impact Awards  Imagine & Believe
 Orphan Product                                    Program
 Breakthrough Summit
 
Voices of                40th Annual Family       Congress Sponsorship
 Determination, An        Conference
 Evening to Benefit
 NTSAD
 
Family Camp              Massachusetts Advocacy   New England Hemophilia
                          Days                     Association 9th
                                                   Annual Walk
 
Face Forward             OhioHealth Multiple      Conference Sponsorship
 Campference and Year-    Sclerosis Wellness
 Round Programming for    Program
 Youth With Rare
 Genetic Disorders
 
Patient Assistance       Multiple Myeloma         2018 Myeloma Patient
 Program                  Community Meetings       Cafe
 
Patient Assistance       Patient Assistance       Patient Assistance
 Program                  Program                  Program
 
Patient Assistance       Patient Assistance       Walk for PKD
 Program                  Program
 
2018 Boston Walk for     2018 PKD Connect         25th Annual Scientific
 PKD                      National Conference      Retreat
 
PHEN Rally Against       TORCH award donation     Beyond the Diagnosis
 Prostate Cancer
 
Rare New England Inc.    RNE Honors Rare Disease  Patient Education and
                          Day Speakers Series      Awareness Program
                          2019
 
2018 RMMSC Annual        2018 MS4MS (Multiple     Rocky Mountain MS
 Fundraiser               Summits for MS)          Center's Spring
                                                   Education Summit
 
2018 Conversations on    2018 Webinar Series      LCA and IRD Community
 MS                                                Outreach and
                                                   Education
 
70th NHF Bleeding        Patient Assistance       LLS Light The Night
 Disorders Conference     Program                  Events
 
Website Update Project   Congress Sponsorship     21st International
                                                   Thyroid Cancer
                                                   Survivors' Conference
 
Patient Education and    Patient Education and    2018 Future Without MS
 Awareness Program        Awareness Program        Fundraiser
 
Donate Life Transplant   Autumn Walks             Fiscal Year 2018
 Games
 
Patient Meeting          Patient Meeting          Experts in Arthritis
                                                   Program
 
Access Program           Corporate Sponsorship    Marrow on the Move
 
14th Annual SEA Blue     Us TOO Prostate Cancer   TORCH award donation
 Prostate Cancer Walk &   Regional Educational
 Run                      Symposiums
 
5th Annual Living Like
 a Warrior Gala
 


                                      Independent Medical Education Grants
                                           1st Jan 2018-31th Mar 2018
    Sanofi US and its affiliate Genzyme Corporation are committed to supporting independent medical education
  activities in therapeutic areas in which the Company is involved, for healthcare professionals, patients, and
   consumers to improve patient care and health outcomes in therapeutic areas in which the Company is engaged.
        Sanofi US and Genzyme Corporation are part of the Sanofi Group, a global pharmaceutical company.
----------------------------------------------------------------------------------------------------------------
                                                                                                 Funding Amount
        Recipient Name(s) \1\                              Activity Title                           ($) \2\
----------------------------------------------------------------------------------------------------------------
University of Kansas Continuing        2017 Muscle Study Group Scientific annual Meeting--               25,000
 Education & Professional Development   Neuromuscular Therapeutics: Bench to Bedside and
                                        Beyond
 
National Jewish Health PVI Peerview    PeerView inPlay and inClinic: ``Optimizing Asthma                209,000
 institute for Medical Education Inc.   Control Through Accurate Identification, Evidence-
                                        Based Management and Targeted Therapeutic Options''
 
Aventura Hospital                      Miami Thyroid Oncology Symposium                                  10,000
 
AcademicCME, LLC.                      ASCO GU 2018: A Clinical Analysis of Optimal                      82,300
                                        Therapeutics to Improve Outcomes in Patients with
                                        Prostate Cancer
 
The Medical College of Wisconsin,      PeerView Live at BMT 2018, ``Integrated Myeloma                   88,555
 Inc. PVI, PeerView Institute for       Management & Enhanced Patient Outcomes: The
 Medical Education, Inc.                Conjunction of Novel Therapeutic Platforms,
                                        Innovative Agents, and Stem Cell Transplant''
 
American Society of Transplant         18th Annual State of the Art Winter Symposium The                 75,000
 Surgeons                               Future Is Now: Saving More Lives Through
                                        Transplantation
 
The Medical College of Wisconsin,      Optimal Use of Stem Cell Mobilization in Patients with           305,000
 Inc. Carden Jennings Publishing        Multiple Myeloma and Non-Hodgkin's Lymphoma
 
Medical Learning Institute PVI,        PeerView inReview, ``Assessing the Potential Impact of           104,250
 PeerView Institute for Medical         New Consensus Recommendations and Ongoing Clinical
 Learning                               Trials of Emerging Therapies on the Diagnosis and
                                        Treatment of Acid Sphingolmyelinase Deficiency''
 
National Society of Genetic            New Lysosomal Storage Disease Healthcare Advocate                 42,637
 Counselors (NSGC)                      Workshop 2018
 
American Society of Clinical           2018 Genitourinary (GU) Cancers Symposium: Translating            30,000
 Oncology, Inc. Conquer Cancer          Evidence to Multidisciplinary Care
 Foundation of the American Society
 of Clinical Oncology
 
American Association of Clinical       Advances in Medical & Surgical Management of Thyroid              15,000
 Endocrinologists                       Cancer
 
ScientiaCME LLC                        Atopic Dermatitis (AD): Best Practices, Barriers to               19,100
                                        Care, and Emerging Therapies in Medication Management
 
Potomac Center for Medical Education   Risk-Benefit Analysis and Personalized Treatment in              100,000
 Rockpointe Corporation                 Multiple Sclerosis: Basing Treatment Goals on the
                                        Latest Evidence
 
Elsevier Office of Continuing Medical  Moving from Treating Atopic Dermatitis Symptoms to               165,000
 Education ASiM CE, LLC                 Treating Underlying Pathology
 
University of Cincinnati Advances in   MauiDerm 2018                                                     50,000
 Cosmetics and Medical Dermatology
 
Postgraduate Institute for Medicine    The Rheumatoid Arthritis Vital Education Initiative:             264,800
                                        New Horizons in Therapeutic Options (RAVE: New
                                        Horizons)
 
American Society for Blood and Marrow  American Society for Blood and Marrow Transplantation             65,000
 Transplantation                        New Investigator Award
 
UT Southwestern Medical Center         40th Annual Carrell-Krusen Neuromuscular Symposium                 5,000
 
Regents of the University of           6th Annual UC San Diego Essentials and Advances in                 5,000
 California                             Apheresis
 
Physicians' Education Resource         Multiple Sclerosis: A Treatment Paradigm Shift when               85,100
                                        Time is Brain
 
Physicians' Education Resource, LLC    2018 New York GUTTM: 11th Annual Interdisciplinary                50,000
 (PER)                                  Prostate Cancer Congress
 
National Comprehensive Cancer Network  NCCN 23rd Annual Conference: Improving the Quality,               25,000
                                        Effectiveness, and Efficiency of Cancer CareTM
 
UNTHSC                                 Overcoming Persistent Barriers to Effective Management            72,500
                                        of Atopic Dermatitis
 
Cleveland Clinic Educational           2018 Nephrology Update                                            10,000
 Foundation
 
Medical Learning Institute, Inc. PVI,  PeerView in Session, ``New Developments in Allergic              168,730
 PeerView Institute for Medical         and Inflammatory Diseases: Clinical Updates From San
 Education, Inc.                        Diego and Orlando''
 
Penn State College of Medicine PVI,    Science and Stories: Navigating the Prostate Cancer               90,000
 PeerView Institute for Medical         Landscape: Urologists at the Intersection of Emerging
 Education Inc.                         Evidence and Patient Centric Care
 
UMA Education Inc., dba Global         Cutting Edge of Transplantation 2018: Breaking through            40,000
 Education Group American Society of    Regulatory Barriers to Unleash Transplant Innovation
 Transplantation                        to Success
 
American College of Rheumatology       2018 ACR Rheumatology Courses                                     75,000
 
PRIME Education, LLC                   Global Perspectives on Current and Emerging Biologic             151,341
                                        Therapies for Rheumatoid Arthritis
 
The Medical College of Wisconsin,      The 28th Annual International Prostate Cancer Update              10,000
 Inc. Carden Jennings Publishing Co.,   (IPCU 28)
 Ltd.
 
NYU Post-Graduate Medical School       NYU Langone Seminar in Advanced Rheumatology                      20,000
 
AcademicCME, LLC.                      Individualizing Treatment Plans to Reduce Disease                 75,000
                                        Activity in Patients with Rheumatoid Arthritis
 
Physicians' Education Resource, LLC    Medical Crossfire: Personalizing Care for Multiple               75,000
 (PER)                                  Myeloma Patients: Current and Future Sequencing
                                        Strategies
 
American College of Surgeons           The changing face of thyroid cancer management for                40,900
                                        surgeons: real-life applications of the new ATA
                                        guidelines
 
Penn State College of Medicine PVI,    PeerView Live at ASCO 2018: ``How I Think, How I                  75,000
 PeerView Institute for Medical         Treat: A Personal Look at Innovative Therapy and
 Education, Inc.                        Meeting Patient Needs in Multiple Myeloma''
 
UMA Education Inc., LLC dba: Global    Evolving Management Strategies for Moderate-to-Severe            346,647
 Education Group (GLOBAL)               Atopic Dermatitis: Looking Beyond Barriers to
                                        Optimized Therapy
 
Physicians' Education Resource, LLC    Advances InT Supportive Care: An Onco-Nurses Guide to             50,000
 (PER)                                  Managing Cancer Treatment-Related Toxicities
 
National Association of Managed Care   Exploring the Challenges of Severe Asthma:                        45,000
 Physicians                             Implementing Personalized Treatment Plans for
                                        Improved Patient Outcomes
 
National Association for Continuing    Conversations in Dermatology The Evolving Paradigm in             59,000
 Education                              Atopic Dermatitis: Integrating Evolving Treatments to
                                        Improve Outcomes
 
Eastern Virginia Medical School        Multiple Sclerosis Symposium 2018                                  5,000
 
University of Kansas Medical Center    Neuromuscular Review Course                                       25,000
 
American Academy of Pas Medical        Moving Toward Improved Outcomes in MS: How PAs Can                50,000
 Logix, LLC                             Make a Difference
 
Med-IQ, LLC                            Preventing Tumor Lysis Syndrome: Risk Assessment and              75,000
                                        Appropriate Prophylaxis
 
Cleveland Clinic Educational           Cleveland Clinic Neurological Institute Summit 2018:              50,000
 Foundation                             MS Treatment Strategies
 
Johns Hopkins University School of     14th Annual Advances in the Diagnosis and Treatment of            30,000
 Medicine                               the Rheumatic Diseases
 
National Association of Managed Care   Implementing Newer Biologic Therapies to Improve                  57,000
 Physicians                             Economic and Clinical Outcomes in Patients with
                                        Moderate to Severe Atopic Dermatitis
 
Annenberg Center for Health Sciences   Master Class for Oncologists                                      30,000
 at Eisenhower Dana Farber Cancer
 Institute
 
Elsevier Office of Continuing Medical  Rising to the Challenge: Diagnosis and Optimal                   124,000
 Education ASiM CE LLC Dannemiller      Management of Atopic Dermatitis in the Primary Care
                                        Setting
 
National Association of Managed Care   Novel Treatment Advances and Approaches in Rheumatoid             45,000
 Physicians                             Arthritis: Personalizing Therapy for Improved
                                        Clinical and Economic Outcomes
 
National Kidney Foundation             Managing the Life-Long Impact of Fabry Disease                   265,995
 
Annenberg Center for Health Sciences   Optimal Treatment sequencing in Metastatic Castration-            65,000
 at Eisenhower PlatformQ Health         Resistant Prostat Cancer: Expert Analysis through
 Education, LLC                         Case Studies
 
Michael J Fox Foundation               MDS-PAS Movement Disorders School for Neurology                   20,000
                                        Residents
 
Penn State College of Medicine PVI,    Science and Stories at ASCO 2018: Making an Impact in            100,000
 PeerView Institute for Medical         Prostate Cancer--Using Expert Experience and Evidence
 Education, Inc.                        to Personalize the Complex Treatment Landscape
 
Purdue University Clinical Care        Advancing Care in Prostate Cancer: Aligning Your                  80,000
 Options, LLC                           Practice With Rapidly Evolving Standards of Care
                                        Throughout the Disease Continuum
 
Continuing Education Alliance          2018 PCE Oncology Symposia Series Segment: Sequencing            125,000
                                        Therapy in Patients with Castration-Resistant
                                        Prostate Cancer
 
University of Chicago                  At the Forefront of Hepatology                                     5,000
 
National Association of Managed Care   The Value of Personalized Treatment Sequencing for                45,000
 Physicians                             Castration-Resistant Prostate Cancer
 
Vindico Medical Education, LLC         Immunology Bootcamp                                              100,000
 
American Urological Association        2018 Evidence-based Clinical Management of Advanced              100,000
                                        and Castration-Resistant Prostate Cancer
 
International Transplant Nurses        European Transplant Nursing Symposium                             10,000
 Society
 
UMA Education Inc., dba Global         R.A.P.I.D.--Rheumatoid Arthritis: A Primary Care                200,000
 Education Group FACTORx MedEd          Initiative for Improved Diagnosis and Outcomes
 Consulting Improve CME, LLC NACE Pri-
 Med Indegene, Inc.
 
Postgraduate Institute for Medicine    The Learning Pathway in Atopic Dermatitis: Maximizing            362,310
                                        Positive Outcomes for Your Patients
 
American Urological Association        AUA 2018 Highlights in Advanced and Castration-                   80,000
                                        Resistant Prostate Cancer
 
PESI Inc.                              15th Annual World Congress on Insulin Resistance,                 50,000
                                        Diabetes & Cardiovascular Disease
 
Horizon CME                            Improving the Quality of Care in Patients with                   237,900
                                        Diabetes through a Simulated QI Experience
 
Joslin Diabetes Center                 Long-acting Insulins in Treatment of Type 2 Diabetes:            324,500
                                        Aligning Provider and Patient Perspectives to Address
                                        Therapeutic Barriers
 
Boston University School of Medicine   Balancing Glycemic Control and Hypoglycemia in T2DM:             435,000
 Practicing Clinicians Exchange (PCE)   the Role of long-acting Basal Insulin Analogues
 
Physicians' Education Resource         Physiologic Insulin Replacement: Practical Strategies            105,650
                                        for Insulin Initiation and Titration of Long-Acting
                                        Insulins
 
University of Massachusetts Medical    The Foundational role of Physiologic, long-acting                341,000
 School CMEducation Resources           Basal Insulin: Optimizing the safety-efficacy
                                        equation in vulnerable patients with T2D
 
Postgraduate Institute for Medicine    Targeting diabetic patients for Physiologic, long-               496,200
 CMEducation Resources                  acting Basal Insulin therapy--A best practice roadmap
                                        to clinical success
 
The Endocrine Society Institute for    Diabetes Masters Series 2018: Getting to the heart of            249,885
 Medical and Nursing Education, Inc.    the matter: Multidisciplinary perspectives on patient-
                                        centered care in T2DM
 
American Association of Diabetes       Leveraging CDEs to Improve Individualized Management           1,024,440
 Educators                              of T2D: Focus on Injectable Therapies
 
Pharmacy Times Continuing Education    An American Journal of Managed Care Medical Crossfire:           202,150
                                        Evaluating New Generation Basal Insulin Therapy
 
American Association of Nurse          The I's Have It: Improving Insulin Initiation Inertia            358,557
 Practitioners                          A Nurse Practitioner-Led Quality Initiative
 
Pri-Med Institute, LLC                 Newer Long-acting Insulins: A Physiologic Approach to            721,504
                                        Glucose Control
 
National Association for Continuing    Clinical Updates for NPs and PAs: 2018--Advances in              244,585
 Education                              Insulin Therapy: Another Step Closer to a More
                                        Physiological Strategy
 
Institute for Medical and Nursing      AAFP 2018: Building Basal Knowledge: Establishing a              374,867
 Education, Inc.                        Solid Foundation for Using New Options in Basal
                                        Insulin for T2DM
 
NACCME, LLC                            Incorporating Long-Acting Insulin Therapy into the               180,565
                                        Physiologic Approach to Diabetes Management
 
Postgraduate Institute for Medicine    Multi-Mechanistic, Insulin-Based Approaches for                  347,000
 CMEducation Resources                  Achieving HA1c/PPG Targets and Optimizing Safety in
                                        Challenging Patients with T2D
 
Pharmacy Times Continuing Education    Emerging Strategies for the Safe and Effective                    81,303
                                        Treatment of Uncontrolled Diabetes: The Application
                                        of Fixed Ratio Combination Insulin/GLP-1 RA Options
 
Boston University School of Medicine   Type 2 Diabetes: New Treatment Combinations for Early            870,000
 Practicing Clinicians Exchange         and Aggressive Glucose Control
 
Postgraduate Institute for Medicine    Complementary insulin-based approaches for achieving             935,000
 CMEducation Resources                  HA1c/PPG targets and optimizing safety in patients
                                        with T2D: A best practice roadmap
 
American Academy of PAs                Achieving Quality Measures in T2DM: Addressing                   199,600
                                        Clinical Inertia and Patient Needs with Complementary
                                        Insulin-Based Therapies
 
National Association for Continuing    Clinical Updates for NPs and PAs: 2018--Combination              244,585
 Education                              Basal Insulin and GLP-1 RA Therapy: A Physiologic
                                        Approach to Diabetes Care
 
North Carolina Academy of Family       Ready, set, action: An intervention to combat clinical           372,477
 Physicians Med-IQ, LLC                 inertia and reduce prolonged hyperglycemia in T2DM
 
Pharmacy Times Continuing Education    The Advent of Insulin/GLP-1 RA Fixed-Ratio Agents for            129,020
                                        Uncontrolled Diabetes: Moving Past the Barriers of
                                        Clinical Inertia
 
Pri-Med Institute, LLC                 Treatment Intensification in T2DM: A Pathophysiologic            721,504
                                        Approach to Combining GLP-1 Receptor Agonists with
                                        Basal Insulin
 
American Association of Clinical       Endocrine University: Lipids Module                                4,000
 Endocrinologists
 
Elsevier Office of Continuing Medical  Raising the Bar by Lowering the Target: Integrating              419,083
 Education Integritas Communications    PCSK9 Inhibitors into Hypercholesterolemia Management
 
University of Tennessee College of     Breaking Barriers to Diabetes Control with GLP-1RA/              165,000
 Pharmacy                               Insulin Combination Agents: Opportunities for the
                                        Community Pharmacist
 
American Association of Nurse          Advances in Diabetes Management: Titratable Fixed-               235,873
 Practitioners                          Ratio Combination Therapy and its Role in T2DM
                                        Treatment
 
University of California, San Diego    Comparing and Contrasting Basal Insulin Strategies in            481,775
                                        Type 1 and Type 2 Diabetes
 
University of Massachusetts Medical    The Mechanistic and Therapeutic Rationale for Dual               342,750
 School CMEducation Resources           SGLT1/2 Inhibition in Adults with Type 1 Diabetes                      Collaboration \4\
 
American Association of Clinical       AACE 2018--Reflecting on the Data Pool: Emerging Roles           357,151
 Endocrinologists Institute for         for SGLT1 and SGLT2 Inhibition in T1DM                                 Collaboration \4\
 Medical and Nursing Education, Inc.
 
American Association of Diabetes       Reducing Glycemic Variability in Type 1 Diabetes: An             333,715
 Educators E&S MedEd Group, Inc.        Exploration of Non-Insulin Treatment Options                           Collaboration \4\
 
Medscape LLC                           Maximizing Medical Management of Knee Osteoarthritis:            174,500
                                        Use of Injectable Therapy
 
Oakstone Publishing, LLC. PeerVoice    Reducing Cardiovascular Risk in Patients With                    374,288
 America Limited                        Dyslipidemia: What Do We Know Now? (And What Should                    Collaboration \3\
                                        We Do About It?)
 
Pharmacy Times Continuing Education    Managing Hypercholesterolemia: Clinical Updates for               85,201
                                        Specialty Pharmacists on PCSK9 Inhibitor Therapy                       Collaboration \3\
 
Postgraduate Institute for Medicine    The Landmark Evidence and Clinical Rationale for PCSK9           486,800
 CMEducation Resources                  Inhibition in the diabetic patient                                     Collaboration \3\
 
Preventive Cardiovascular Nurses       2018 PCNA Dyslipidemia Campaign                                   60,000
 Association                                                                                                   Collaboration \3\
 
Oakstone Publishing, LLC. PeerVoice    Modern Management of Lipid-Related Cardiovascular Risk           375,000
 America Limited                        in Patients With Dyslipidemia                                          Collaboration \3\
 
UMA Education, Inc. dba Global         Mastering the Prior Authorization Process to Meet                275,000
 Education Group                        Patient Needs                                                          Collaboration \3\
----------------------------------------------------------------------------------------------------------------
\1\ Applicant names are provided by the requestor. If applicants apply as a group for a single educational
  activity; all applicants may be not be identified above. The Company funds other educational activities
  (including fellowships and non-physician and patient education); all of which do not appear on this report,
  but appear on other reports on this site.
\2\ ``Funding Amount'' is the amount that the Company funded during Q1, 2018 identified above based upon an
  agreement. Recipients are required to return any unused funds. Information on unused funds returned by the
  applicant on activities are not reported. "Funding Amount" does not include funds that may have been provided
  by other affiliated Sanofi Company Entities (e.g., Sanofi Pasteur).
\3\ Collaboration (Shared) Funding--is the full amount of a grant funded under an agreement with Regeneron, some
  or all of which may be shared between the collaborating entities.
\4\ Collaboration (Shared) Funding--is the full amount of a grant funded under an agreement with Lexicon, some
  or all of which may be shared between the collaborating entities.


                                      Independent Medical Education Grants
                                          1st April 2018-30th June 2018
    Sanofi US and its affiliate Genzyme Corporation are committed to supporting independent medical education
  activities in therapeutic areas in which the Company is involved, for healthcare professionals, patients, and
   consumers to improve patient care and health outcomes in therapeutic areas in which the Company is engaged.
        Sanofi US and Genzyme Corporation are part of the Sanofi Group, a global pharmaceutical company.
----------------------------------------------------------------------------------------------------------------
                                                                                                 Funding Amount
        Recipient Name(s) \1\                              Activity Title                           ($) \2\
----------------------------------------------------------------------------------------------------------------
Med-IQ, Inc.                           Getting Social About Multiple Sclerosis: Tools for                75,000
                                        Newly Diagnosed Patients and Their Care Teams
 
National Association of Managed Care   Building a Better Understanding in Asthma Management:             57,000
 Physicians                             Best Practices for Treatment and Control
 
Excel Continuing Education             Exploring the Genetics and Management of Fabry Disease            69,720
 
The Trustees of Columbia University    The Columbia Renal Biopsy Course                                   5,000
 in the City of New York
 
Rheumatology Nurses Society Medscape   Updates in RA, PsA, and Biosimilars: A Pipeline View              50,000
 Education                              for the Clinical Nurse
 
University of Illinois at Chicago      Illinois Transplant Pharmacists Association Symposium              8,000
 College of Pharmacy
 
Rush University Medical Center Plexus  Northern California Genitourinary Malignancy                      10,000
 Communications                         Symposium: Translating Clinical Advancements to
                                        Practical Patient Care
 
Medscape, LLC                          Managing Multiple Myeloma: What's Next?                          116,000
 
University of Louisville Research      11th Annual Perspectives in Rheumatic Diseases,                   30,000
 Foundation Inc. Global Academy for     presented by Rheumatology News, Internal Medicine
 Medical Education Postgraduate         News, Family Practice News
 Institute for Medicine
 
AKH Inc, Advancing Knowledge in        Focusing on the Patient Voice: Utilizing Components of           100,000
 Healthcare 47-Consultants in Medical   a Patient Coach Module Contextually within Patient-
 Education                              Centric CME Activities
 
University of Colorado Denver          Forty-fifth annual Renal Disease and Electrolyte                   5,000
                                        Disorders Course
 
Annenberg Center for Health Sciences   Advancing Knowledge to Practice: Optimizing Severe               200,000
 at Eisenhower                          Asthma Care in the Age of Biologics
 
USF Health i3 Health                   Challenges and Opportunities in Metastatic Castration-            90,000
                                        Resistant Prostate Cancer: A CME/CE/CPE-Certified VA/
                                        DoD Meeting Series
 
Projects In Knowledge @Point of Care   Multiple Sclerosis @Point of Care                                 75,000
 
New Jersey Academy of Family           Ascertaining the Role of the Primary Care Clinician in             5,000
 Physicians                             the Recognition and Management of Patients With
                                        Multiple Sclerosis in the Modern Era
 
Med Learning Group                     Pathology-Based, Targeted Therapies--Managing Moderate-          124,745
                                        to-Severe Atopic Dermatitis in Adults
 
Annenberg Center for Health Sciences   2018 SUNA Advanced Prostate Cancer Grant                          30,000
 at Eisenhower Prostate Cancer
 Education Council
 
Consortium of Multiple Sclerosis       Immune Dysfunction in Multiple Sclerosis: Modern                  75,000
 Centers Catamount Medical Education    Considerations in Treatment and Management
 
Dallas County Optometric Society       Eyes on Fabry Dallas County Optometric Society                     9,266
 Fabry Support & Information Group
 
Association of Reproductive Health     Snap, Crackle and Pop: Provider Education and Targeted            52,000
 Professionals                          Training to Improve the Diagnosis and Therapeutic
                                        Management of Rheumatoid Arthritis in Female Patients
 
AcademicCME                            Improving Individualized Outcomes in Asthma with                  45,000
                                        Evidence-based Treatment Strategies
 
Integrity Continuing Education, Inc.   2018 Asthma State Society CME Meetings and BioDigital            319,350
                                        Human On-demand Simulation Activity--Improving Severe
                                        Asthma Control through Comprehensive Patient
                                        Assessment and Tailored Treatment Selection
 
UMA MLG, LLC                           Targeted Therapies for the Management of Moderate-to-            249,975
                                        Severe Atopic Dermatitis in Adults--Animated
                                        Whiteboard View
 
Society for Investigative Dermatology  Neuro-Immunology of Skin Symposia                                 75,000
 
Penn State College of Medicine PVI,    PeerView Live: ``Unraveling the Complex Treatment                 60,000
 PeerView Institute for Medical         Landscape for Prostate Cancer: Guidance for
 Education, Inc.                        Delivering Evidence-Based, Patient-Centered Care''
 
Medscape, LLC                          Minimizing the Effects of TLS and CRS in Patients with            74,000
                                        Hematologic Malignances
 
Excel Continuing Education             Unraveling the Genetics and Management of MPS 1                   55,565
 
Hereditary Disease Foundation          Hereditary Disease Foundation's ``Milton Wexler                   10,000
                                        Celebration of Life'' Symposium of international
                                        Huntington's disease researchers
 
Medscape LLC                           Targeted Therapies for the Management of Severe                  261,500
                                        Asthma: Surveying an Evolving Landscape
 
Seattle Children's Hospital            PLUGS Summit 2018: Clinical Laboratory Stewardship:                8,000
                                        Where Patient Safety and Financial Responsibility
                                        Meet
 
University of Cincinnati Global        Skin Disease Education Foundation's 14th Women's &                10,000
 Academy for Medical Education          Pediatric Dermatology Seminar
 Postgraduate Institute for Medicine
 
Physicians' Education Resource, LLC    2018 ASH Symposium: ``D'' is for Diagnosis: Solving              250,000
 (PER)                                  the Mystery of Rare Hematologic Disorders
 
Boston University School of Medicine,  Practical Approach to Electromyography and                         7,500
 CME                                    Neuromuscular Disorders Conference
 
Specialty Pharma Education Center      Renal Transplantation: Overview of Advances in                    49,750
                                        Clinical Understandings, Guidelines, and Treatment &
                                        Management Strategies
 
University of California Irvine        8th Annual UC Irvine Neuromuscular Colloquium                     20,000
 
Physicians' Education Resource, LLC    Oncology BriefingsTM: Current Perspectives on                     50,000
 (PER)                                  Preventing and Managing Tumor Lysis Syndrome
 
UMA Education Inc., dba Global         Nursing Management of Treatment-Related Side Effects             120,000
 Education Group MCM Education          in Metastatic Prostate Cancer
 
UMA Education Inc., dba Global         A Quality Improvement (QI) Educational Pilot on                  107,155
 Education Group Q Synthesis, LLC       Enhancing Prostate Cancer Management in Urology
                                        Practice
 
Med Learning Group                     Evolving Therapeutic Options for Moderate-to-Severe              274,785
                                        Asthma: A Comprehensive 3-Dimensional Study
 
University of Cincinnati               2018 International Rare Lung Diseases Research                    10,000
                                        Conference
 
Consortium of Multiple Sclerosis       Therapeutic Decision-Making for Disease Modification              49,288
 Centers Inc. Delaware Media Group      in MS: 2018 Update
 
Excel Continuing Education             Unraveling a Therapeutic Conundrum: ASMD Niemann Pick            106,790
                                        Disease
 
University of Cincinnati Advances in   MauiDerm NP+PA Summer 2018                                        25,000
 Cosmetic and Medical Dermatology
 
American Thoracic Society              ATS 2018 International Conference - Selected Sessions             20,000
                                        in Asthma
 
Creighton University Physicians        Skin of Color Seminar Series 2018 (SOCSS 2018)                    15,000
 Continuing Education, Corporation
 
UMA MLG, LLC                           Treating a Chronic Autoimmune Inflammatory Disease:              214,500
                                        Targeting Pathophysiologic Cytokines in the
                                        Management of Rheumatoid Arthritis--Animated
                                        Whiteboard View
 
Tarrant County Organization Society    Eyes on Fabry Tarrant County Optometric Society                    7,998
 Fabry Support & Information Group
 
University of Nevada, Reno School of   2018 Real World Dermatology for PAs and NPs                       25,000
 Medicine Dermatology University LLC
 
American Society of Clinical           2018 ASCO Annual Meeting Genitourinary Cancer Tracks              40,000
 Oncology, Inc. Conquer Cancer          Bundle (Prostate and Nonprostate)
 Foundation of the American Society
 of Clinical Oncology
 
Postgraduate Institute for Medicine    Clinical Care Team Exchange: The Role of New Biologics           425,170
                                        for Optimal RA Management
 
PRIME Education, LLC                   Driving Practice Change in Systems-Based Care of                 344,805
                                        Patients with Atopic Dermatitis
 
The Medical College of Wisconsin,      The 23rd Annual Southwest Prostate Cancer Symposium                5,000
 Inc. Carden Jennings Publishing Co.,   (SPCS 23)
 Ltd
 
St. Joseph's Regional Medical Center   Acute Rejection of the Allograft--New Concepts and Old             1,810
 
MS Cure Fund, Inc.                     2018 Q1 Lifestyle Management Patient Education                    20,000
                                        Programs for individuals diagnosed with multiple
                                        sclerosis, and their support team.
 
Alaska Regional Hospital               Wheezin', Sneezin' & Itchin' in Alaska                             5,000
 
American Academy of PAs                AAPA 2018--Rheumatology Track                                      5,000
 
Postgraduate Institute for Medicine    The Specialty Pharmacy Review BoardTM--Examining                 235,000
 Impact Education, LLC                  Emerging Biologics for Difficult-to-treat or Severe
                                        Asthma
 
National Association of Managed Care   Individualizing Therapy in the Management of Relapsing            45,000
 Physicians                             Multiple Sclerosis: Expert Switching and Sequencing
                                        Strategies
 
Consortium of Multiple Sclerosis       Nursing Care in Multiple Sclerosis: Evidence-Based                75,000
 Centers Inc. International             Practice
 Organization of MS Nurses
 
The Annenberg Center for Health        How I Treat Advanced Prostate Cancer: Making Sense of            100,000
 Sciences at Eisenhower prIME           the Ever-Increasing Options
 Oncology, LLC
 
Elsevier Office of Continuing Medical  Clinical Issues in Atopic Dermatitis: Discussions and            784,642
 Education Integritas Communications    Debates on Managing Moderate-to-Severe Disease
 
Horizon CME, Inc.                      How to Select and Start Insulin in Patients with Type             59,925
                                        2 Diabetes: A Hands-on Workshop
 
National Assocation For Continuing     Getting Comfortable with Insulin: New Approaches to              355,396
 Education                              Getting Patients Safely to Target
 
Medscape LLC                           Improving Use of Basal Insulin for Better Diabetes               800,000
                                        Outcomes
 
Pri-Med Institute, LLC (d/b/a pmiCME)  The Southern Diabetes Initiative: Individualizing Care           400,000
                                        in the 21st Century
 
Elsevier Office of Continuing Medical  Emerging Strategies for Achieving Glycemic Control in            179,950
 Education                              Adults with Type 1 Diabetes                                            Collaboration \4\
 
The France Foundation                  When Insulin Isn't Enough: Exploring Dual SGLT1 and              153,900
                                        SGLT2 Inhibition in T1DM                                               Collaboration \4\
 
NACCME, LLC.                           Integrating Emerging Evidence in Adjunctive Therapies            432,535
                                        Into Team-Based Management Strategies in Type 1                        Collaboration \4\
                                        Diabetes
 
Med-IQ, LLC                            Evolving Evidence in Type 1 Diabetes Management:                 238,281
                                        Evaluating the Role of SGLT Inhibition                                 Collaboration \4\
 
UMA Education Inc., dba Global         Type 1 Diabetes: New and Emerging Therapeutic                    511,628
 Education Group                        Strategies to Address Unmet Needs                                      Collaboration \4\
 
Haymarket Medical Education            GLP-1 Receptor Agonists: Injecting More Confidence in             49,950
                                        Achieving Glycemic Control for Patients With T2DM The
                                        my CME Town Wall: A Live Clinical Forum for Multiple
                                        Viewpoints on a Virtual Stage
 
Medscape LLC                           Novel Treatments for T1D                                         499,000
                                                                                                               Collaboration \4\
 
Med-IQ, Inc.                           Initiating Insulin in Patients Who Fear Needles: Using           297,385
                                        Evolving Basal Insulins to Improve Adoption
 
National Association of Managed Care   The Role of PCSK9 Inhibitors in Lowering LDL-C in                 95,000
 Physicians                             Patients with Dyslipidemia: What Managed Care Needs                    Collaboration \3\
                                        to Know
 
Allina Health Minneapolis Heart        PCSK9 Inhibitors--Science, Selection and Access                    5,000
 Institute Foundation                                                                                          Collaboration \3\
 
Medscape LLC                           PCSK9 Inhibitors and Cardiovascular Outcomes: ACC 2018           237,125
                                        Data You Cannot Afford to Miss                                         Collaboration \3\
 
Postgraduate Institute for Medicine    The Landmark trial-based evidence and rationale for              398,000
 CMEducation Resources, LLC             PCSK9 inhibition to prevent and treat Atherosclerotic                  Collaboration \3\
                                        Cardiovascular Disease (ASCVD)
 
National Lipid Association Horizon     PCSK9 Inhibitors in Practice: Real-World Challenges              261,335
 CME, Inc.                              and Solutions                                                          Collaboration \3\
 
National Lipid Association             The New Era of Preventive Cardiology: Applying PCSK9             153,000
                                        Inhibitor Therapeutics to Prevent Heart Attack and                     Collaboration \3\
                                        Stroke
 
Postgraduate Institute for Medicine    New Evidence-Based, Therapeutic Strategies for                   397,000
 CMEducation Resources, LLC             applying CV outcome and trialbased evidence for PCSK9                  Collaboration \3\
                                        inhibition to the front lines of CAD Prevention and
                                        Treatment
 
Med Learning Group                     A Virtual Reality Tour of Nonstatin LDL-C-lowering               573,725
                                        Agents that Decrease Cardiovascular Risk for Patients                  Collaboration \3\
                                        with Persistent Hypercholesterolemia
 
Potomac Center for Medical Education   Role of Interventional Cardiologists in Secondary                198,450
                                        Prevention of Myocardial Infarction: Redefining                        Collaboration \3\
                                        Clinical Practice
 
North American Center for Continuing   Cardiology Grand Rounds: Overcoming Access Barriers              476,838
 Medical Education, LLC                 and Practice Challenges to PCSK9 Inhibitor                             Collaboration \3\
                                        Implementation
 
PRIME Education, LLC                   Applying the Latest Cardiovascular Outcomes Trial                146,740
                                        Evidence to PCSK9 Inhibitor Decision-Making in Lipid                   Collaboration \3\
                                        Management
 
Pri-Med Institute, LLC (d/b/a pmiCME)  Translating Evidence to Practice: Improving Outcomes             575,150
 Horizon CME, Inc.                      in Patients with ASCVD with PCSK9 Inhibitors                           Collaboration \3\
 
Med Learning Group                     A Virtual Reality In Practice View: Maximizing                   174,400
                                        Clinical Benefit Through Optimal LDL-C Reductions in                   Collaboration \3\
                                        Patients With Atherosclerotic Disease
 
Physicians' Education Resource         2018 New York Multidisciplinary Cardio-Endo-Renal                 35,000
                                        Collaborative: Access to PCSK9i: Updates on                            Collaboration \3\
                                        Guidelines, Emerging Cardiovascular Benefits and
                                        Overcoming Barriers to Access
 
PRIME Education, LLC                   Integrating Evidence from the Latest Cardiovascular              459,799
                                        Outcomes Data into Managed Care Decision-Making in                     Collaboration \3\
                                        Lipid Management
 
The Academy for Continued Healthcare   Improving Outcomes and Expanding Opportunities for the           180,420
 Learning                               Treatment of Hyperlipidemia                                            Collaboration \3\
----------------------------------------------------------------------------------------------------------------
\1\ Applicant names are provided by the requestor. If applicants apply as a group for a single educational
  activity; all applicants may be not be identified above. The Company funds other educational activities
  (including fellowships and non-physician and patient education); all of which do not appea r on this report,
  but appear on other reports on this site.
\2\ ``Funding Amount'' is the amount that the Company funded during Q2, 2018 identified above based upon an
  agreement. Recipients are required to return any unused funds. Information on unused funds returned by the
  applicant on activities are not reported. ``Funding Amount'' does not include funds that may have been
  provided by other affiliated Sanofi Company Entities (e.g., Sanofi Pasteur).
\3\ Collaboration (Shared) Funding--is the full amount of a grant funded under an agreement with Regeneron, some
  or all of which may be shared between the collaborating entities.
\4\ Collaboration (Shared) Funding--is the full amount of a grant funded under an agreement with Lexicon, some
  or all of which may be shared between the collaborating entities.


                                      Independent Medical Education Grants
                                          1st July 2018-30th Sept 2018
    Sanofi US and its affiliate Genzyme Corporation are committed to supporting independent medical education
  activities in therapeutic areas in which the Company is involved, for healthcare professionals, patients, and
   consumers to improve patient care and health outcomes in therapeutic areas in which the Company is engaged.
        Sanofi US and Genzyme Corporation are part of the Sanofi Group, a global pharmaceutical company.
----------------------------------------------------------------------------------------------------------------
                                                                                                 Funding Amount
        Recipient Name(s) \1\                              Activity Title                           ($) \2\
----------------------------------------------------------------------------------------------------------------
Integrity Continuing Education, Inc.   Advancing Diagnosis and Management of Atopic                     318,450
                                        Dermatitis in Children and Adolescents--
                                        Practitioner's Edge State Society Meeting Series,
                                        CaseScribe On-demand Activity, and Mobile Coach
                                        Platform
 
Penn State College of Medicine PVI,    PeerView inSession, ``An Expert Analysis of New Data              76,740
 PeerView Institute for Medical         for Uncontrolled Persistent Asthma Treatments:
 Education, Inc.                        Clinical Updates From Paris''
 
Medscape LLC                           Advances in Severe Asthma Management: Conference                 219,500
                                        Highlights and Perspectives
 
PRIME Education, LLC                   4th Annual Regional Meetings for Providers in Federal            188,000
                                        and Public Healthcare Sectors: Interprofessional
                                        Education on Psoriatic Diseases, Atopic Dermatitis,
                                        and Rheumatoid Arthritis
 
Medscape LLC                           Guide to Atopic Dermatitis: Clinical Pearls for                  198,400
                                        Dermatologists and Allergists
 
MediCom Worldwide, Inc.                2018 ASH Meeting on Hematologic Malignancies: The Art             25,000
                                        and Science of Relapsed/Refractory Multiple Myeloma:
                                        A Practical Guide to Complex Therapeutic Choices
 
Medscape LLC                           The Pediatrician's Role in Atopic Dermatitis                     458,225
 
Integrity Continuing Education, Inc.   Strategies to Provide Individualized Treatment in                360,900
                                        Moderate-to-Severe Atopic Dermatitis--Practitioner's
                                        Edge State Society Meeting Series and Publication in
                                        Action On-demand Activity
 
Regents of the University of           Frontiers in Autosomal Dominant Polycystic Kidney                 10,000
 California                             Disease (ADPKD)
 
National Association of Managed Care   Optimizing Clinical and Economic Outcomes in the                  57,000
 Physicians                             Management of Moderate to Severe Atopic Dermatitis:
                                        Taking a Closer Look at the Role of Biologic
                                        Therapies
 
National Jewish Health Catamount       What is Multiple Myeloma? A Game-Based Learning                   75,000
 Medical Education, LLC                 Experience on Novel Treatment Strategies for
                                        MultipleMyeloma
 
Medical Learning Institute, Inc. PVI,  PeerView inVision, Expert Insights on Available and              122,250
 PeerView Institute for Medical         Emerging Therapies for the Management Pompe Disease
 Education, Inc.
 
ScientiaCME LLC                        Treatment strategies in Fabry disease                             17,800
 
UMA MLG, LLC                           Utilizing the Molecular/Physiologic Phenotype to                 289,400
                                        Direct Asthma Therapy: A Comprehensive Infographic
                                        View
 
CME Outfitters, LLC                    Atopic Dermatitis: You Can't Improve What You Don't              279,850
                                        Measure
 
The University of Kansas Medical       The Changing Landscape of Neuromuscular Disease: The              40,000
 Center--Continuing Medical Education   Future is Here
 
Oakstone Publishing, LLC.              Getting Under the Skin with Targeted Therapy to                  170,000
                                        Improve Atopic Dermatitis Management
 
University of Cincinnati Global        14th Annual Coastal Dermatology Symposium                         10,000
 Academy for Medical Education
 Postgraduate Institute For Medicine
 
MediCom Worldwide, Inc.                2018 Meeting Highlights of the 4th International                  12,500
                                        Conference on Multiple Myeloma
 
National Comprehensive Cancer Network  NCCN 13th Annual Congress: Hematologic MalignanciesTM             25,000
 
Boston Children's Hospital/Division    Metabolism Conference Series                                      10,000
 of Genetics and Genomics
 
Postgraduate Institute for Medicine    Incorporating New Agents into the Management of Atopic           375,400
 PlatformQ Health Education, LLC        Dermatitis
 Asthma and Allergy Foundation of
 America
 
Purdue University MCM Education        Improving the Management of Severe Asthma in Patients            125,000
                                        with Type 2 Inflammation
 
Cedars-Sinai                           8th Annual Symposium on Lysosomal Storage Disorders               20,000
 
AMERICAN UROLOGICAL ASSOCIATION        Use of Novel Hormonal Agents and Systemic Therapy in              50,000
                                        Advanced Prostate Cancer
 
Med Learning Group                     In Pursuit of Clinical Remission: Optimizing the                 249,850
                                        Pharmacologic Management of Rheumatoid Arthritis
 
Physicians' Education Resource, LLC    Cancer Summaries and CommentariesT: Report from San               50,000
 (PER)                                  Diego on Advancements in Multiple Myeloma
 
Physicians' Education Resource, LLC    2019 ASCO GU Symposium: Prostate Cancer Tumor Board:             100,000
 (PER)                                  Integration of Recent Data Sets Across Lines of Care
 
University of Pittsburgh               2018 Pittsburgh International Lung Conference--                   10,000
                                        Pulmonary Medicine: Basic Biology and Novel Therapies
 
American College of Chest Phys         Update on Moderate-to-Severe Asthma for Specialists:             500,000
                                        Conference Coverage from CHEST 2018
 
American Academy of Physician          10th Annual Allergy, Asthma & ENT CME Conference                   5,000
 Assistants in Allergy, Asthma &
 Immunology
 
Oakstone Publishing, LLC Answers in    Strategies for Success in Rheumatoid Arthritis                   170,000
 CME Inc.                               Treatment: Integrating the Patient Voice
 
American College of Allergy, Asthma &  An interactive Case Discussion of a Young Adult with              40,000
 Immunology                             Severe Atopic Dermatitis: Insights from the Expert
 
UT Southwestern Medical Center         Treatment Approaches and Therapies for Highly Active              83,350
 Medical Logix, LLC                     Multiple Sclerosis: Implementing Updated MS
                                        Guidelines
 
National Association of Managed Care   Implementing Personalized Therapeutic Strategies of               45,000
 Physicians                             Switching and Sequencing to Improve Patient Outcomes
                                        in the Management of Multiple Sclerosis
 
Projects In Knowledge                  MedImage Cases: Multiple Sclerosis                                75,000
 
American Society of Transplant         12 Annual Surgical Fellows Symposium                             110,000
 Surgeons
 
Medscape LLC                           Management Challenges in Rheumatoid Arthritis: A                 250,000
                                        Virtual Simulation Approach
 
Michael J. Fox Foundation For          MDS-PAS Movement Disorders School for Neurology                   20,000
 Parkinson's Research                   Residents
 
Society for Inherited Metabolic        2018 North American Metabolic Academy                             25,000
 Disorders
 
Duke University                        2018 Duke Solid Organ Transplant Summit                           15,000
 
American Society of Nephrology         Fabry Disease for the Nephrologist: Present and Future           125,000
 University of Minnesota
 
American College of Allergy, Asthma &  Thursday Morning Session: Biologic Therapies in Your              77,875
 Immunology                             Practice
 
Physicians' Education Resourcer        Advances inTM Therapies for Patients with Multiple                60,000
 (PER)                                 Myeloma: More Options. More Decisions. Better
                                        Outcomes
 
Oakstone Publishing, LLC Answers in    Making the Case for Stepping Up Therapy for Atopic               185,000
 CME Inc.                               Dermatitis
 
Oakstone Publishing, LLC Answers in    Assessing the Impact of AD: Physical and Beyond                  170,000
 CME Inc.
 
Postgraduate Institute for Medicine    Recognizing and Managing Suboptimal Therapeutic                   35,000
 Enquiring Minds, LLC                   Response in MS: Expert Guidance on Challenging Cases
 
JPatible                               JPatible Jewish Genetic Screening and Couple                      77,500
                                        Compatibility Matching Program
 
Illinois Academy of Physician          Multiple Sclerosis                                                 6,500
 Assistants
 
American Society for Reconstructive    Vascularized Composite Tissue Allografts: What it                 30,152
 Transplantation                        Takes to Succeed
 
Massachusetts Association of           ``Multiple Sclerosis''                                             4,800
 Physician Assistants
 
i3 Health                              Castration-Resistant Prostate Cancer: Implementing New            86,975
                                        Data and Evolving Standards
 
Mayo Clinic College of Medicine and    International Myeloma Society Educational Workshop                50,000
 Science SPARGO Inc. on behalf of the
 International Myeloma Society
 
UCSF Office of CME                     UCSF TRANSPLANT 2018: Pioneering Advances in                       5,000
                                        Transplantation
 
The University of Texas MD Anderson    Emerging Therapeutic Strategies for Relapsed and                  50,000
 Cancer Center ASiM CE, LLC             Refractory Multiple Myeloma: Highlights from ASH 2018
 
Regents of the University of Colorado  88th Annual Meeting of the American Thyroid                       75,000
 American Thyroid Association           Association and the 2018 Annual Ridgway Trainee
                                        Conference
 
National Assocation For Continuing     Matching Pathogenesis and Treatment in Atopic                     92,800
 Education                              Dermatitis: The Evolving Science
 
The Medical College of Wisconsin PVI,  PeerView Live at the 2019 TCT Meetings--``Innovative             119,477
 PeerView Institute for Medical         Therapies and Concepts in Transplant-Eligible
 Education                              Patients With Myeloma: Advancing Toward More
                                        Effective Care Across Treatment Settings''
 
Physicians' Education Resource, LLC    Medical Crossfire: How Can We Best Leverage the Use              50,000
 (PER)                                  of MRD to Optimize Outcomes in the Management of
                                        Hematologic Malignances?
 
Postgraduate Healthcare Education,     Identification and Management of Atopic Dermatitis:              154,500
 LLC Postgraduate Institute for         Applying Advances to Improve Outcomes A PHE/Power-Pak
 Medicine (PIM)                         Initiative Program 2: Treatment and Emerging
                                        Therapies in Moderate-to-Severe Atopic Dermatitis
 
Physicians' Education Resource, LLC    Optimizing Outcomes Through Stem Cell Mobilization:              300,000
 (PER) The Medical College of           Applying Evidence to Patients with Multiple Myeloma
 Wisconsin, Inc.                        and Non-Hodgkin's Lymphoma
 
Continuing Education Alliance          PCE Directed Learning eCourse plus eMinders and                  148,275
                                        Reinforcements: Changing Pathways in Moderate to
                                        Severe Atopic Dermatitis
 
American Academy of CME, Inc.          Reversing the Trend in Living Kidney Donation:                   122,875
                                        Improving Risk Assessment and Increasing Access
 
Postgraduate Institute for Medicine    Applying Precision Medicine in Severe and Difficult-to-          322,100
                                        Treat Asthma.
 
Penn State College of Medicine         Consensus or Controversy? Clinical Investigators                  95,000
 Research To Practice                   Provide Perspectives on the Current and Future
                                        Management of Patients with Prostate Cancer--An
                                        Independent Satellite Symposium (ISS) Held as a
                                        Premium Ancillary Educational Event During the 2019
                                        Genitourinary Cancers Symposium
 
Excel Continuing Education             Newborn Screening for Rare Disorders: Focusing on                 77,575
                                        Pompe Disease and Gaucher Disease
 
Excel Continuing Education             ``Multiple Sclerosis: Treating and Managing Symptoms''             5,000
 
Medical Learning Institute, Inc. PVI,  PeerView inSession, Taking Stock of Late-Breaking Data            50,000
 PeerView Institute for Medical         on Disease-Modifying Therapies for the Treatment of
 Education, Inc.                        Multiple Sclerosis: What Are the Key Learnings from
                                        Berlin?
 
UMA MLG, LLC                           A 3D View: Moderate-to-Severe Atopic Dermatitis in the           425,000
                                        Pediatric Population: Long-term Treatment and Managed
                                        Care Issues
 
Postgraduate Institute for Medicine    A Learning Pathway for Clinicians in Multiple                     50,000
 RMEI                                   Sclerosis: Practical Strategies for Early Diagnosis
                                        and Informed Management
 
Postgraduate Institute for Medical     Atopic Dermatitis: A Specialist Perspective on                   300,000
 Education Global Academy for Medical   Diagnosis and Management Across the Age Spectrum
 Education
 
American Academy of CME, Inc           Crucial Conversations in Rare & Orphan Disease:                   36,000
                                        Challenges of Diagnosing Rare Diseases: A Focus on
                                        Gaucher Disease
 
Consortium of Multiple Sclerosis       Improving Multiple Sclerosis Care: Integrating Patient-           60,000
 Centers PlatformQ Health Education,    Provider Perspectives
 LLC
 
Postgraduate Healthcare Education      The Pharmacist's Role in Managing Disease-Modifying               30,000
 Spire Learning                         Therapies in Adults With Multiple Sclerosis
 
Integrity Continuing Education, Inc.   Improving Diagnosis and Treatment of Atopic Dermatitis           299,800
                                        through Collaborative Primary & Specialist Care--
                                        Practitioner's Edge State Society Meeting Series and
                                        CME Audit and Feedback Practice Assessment
 
Regents of the University of Colorado  Practical Ways to Achieve Targets in Diabetes Care                25,000
                                        (ATDC)                                                                 Collaboration \4\
 
Regents of the University of Colorado  Practical Ways to Achieve Targets in Diabetes Care                50,000
                                        (ATDC)
 
Regents of the University of Colorado  Practical Ways to Achieve Targets in Diabetes Care                75,000
                                        (ATDC)
 
Horizon CME, Inc.                      Can We Do It Better: Improving Outcomes in the                   165,100
                                        Management of Patients with Atrial Fibrillation
 
Integrity Continuing Education, Inc.   2019 AAFP State Society CME Meetings, Hands-on                   160,000
                                        Workshop And BioDigital Human On-demand Simulation
                                        Activity: Overcoming Barriers to Initiating or
                                        Intensifying Insulin Therapy: Best Practices for the
                                        Family Physician
 
NACCME, LLC.                           Cardiology Grand Rounds: Diagnostic and                          221,710
                                        Pharmacotherapeutic Strategies for the Individualized
                                        Management of Atrial Fibrillation
 
University of Cincinnati               New Developments in Type 2 Diabetes Treatment to                 275,000
                                        Decrease the Risk of Hypoglycemia
 
Medscape LLC                           Lipid Clinic Considerations: What Would You Do? A Live           447,220
                                        Patient Simulation                                                     Collaboration \3\
 
PRIME Education, LLC                   Patients, Payers, Providers Opine: When to Treat with            445,879
                                        PCSK9s                                                                 Collaboration \3\
 
Boston University School of Medicine   2018 PCE Series 3 Live and Enduring Home Study with              225,000
 Practicing Clinicians Exchange (PCE)   Eminders and Reinforcement Activities--Evolution of                    Collaboration \3\
                                        Dyslipidemia Management: The Expanding Role of PCSK9
                                        Inhibitors
 
Association of Black Cardiologists,    Managing Lipids and Cardiovascular Risk: Using the               250,000
 Inc.                                   Data to Optimize Care                                                  Collaboration \3\
 
Pharmacy Times Continuing Education    An American Journal of Managed Care (AJMC) Payor and              51,850
                                        Specialty Pharmacy Forum: Discussing Clinical Updates                  Collaboration \3\
                                        and Outcomes Data for PCSK9 Inhibitors
 
Med-IQ, Inc.                           Exploring Treatment Intensification in Type 2                    250,050
                                        Diabetes: Focus on the Provider-Patient Collaborative
 
UMA MLG, LLC                           An In Practice View: Moving Beyond Statins To Decrease           178,150
                                        Cardiovascular Events in Patients With                                 Collaboration \3\
                                        Atherosclerotic Disease
 
Oakstone Publishing, LLC Answers in    Putting Cardiovascular Outcomes Data Into Context: How           170,000
 CME Inc.                               Will the Latest Information on PCSK9 Inhibitors                        Collaboration \3\
                                        Change Practice?
----------------------------------------------------------------------------------------------------------------
\1\ Applicant names are provided by the requestor. If applicants apply as a group for a single educational
  activity; all applicants may be not be identified above. The Company funds other educational activities
  (including fellowships and non-physician and patient education); all of which do not appear on this report,
  but appear on other reports on this site.
\2\ ``Funding Amount'' is the amount that the Company funded during Q3, 2018 identified above based upon an
  agreement. Recipients are required to return any unused funds. Information on unused funds returned by the
  applicant on activities are not reported. ``Funding Amount'' does not include funds that may have been
  provided by other affiliated Sanofi Company Entities (e.g., Sanofi Pasteur).
\3\ Collaboration (Shared) Funding--is the full amount of a grant funded under an agreement with Regeneron, some
  or all of which may be shared between the collaborating entities.
\4\ Collaboration (Shared) Funding--is the full amount of a grant funded under an agreement with Lexicon, some
  or all of which may be shared between the collaborating entities.


                                      Independent Medical Education Grants
                                           1st Oct 2018--31st Dec 2018
    Sanofi US and its affiliate Genzyme Corporation are committed to supporting independent medical education
  activities in therapeutic areas in which the Company is involved, for healthcare professionals, patients, and
   consumers to improve patient care and health outcomes in therapeutic areas in which the Company is engaged.
        Sanofi US and Genzyme Corporation are part of the Sanofi Group, a global pharmaceutical company.
----------------------------------------------------------------------------------------------------------------
                                                                                                 Funding Amount
        Recipient Name(s) \1\                              Activity Title                           ($) \2\
----------------------------------------------------------------------------------------------------------------
NACCME, LLC Horizon CME                Clinical and Cost Considerations for Value-Based                  74,875
                                        Multiple Sclerosis Care
 
AKH, Inc. Catalyst Medical Education,  Improving Care for Patients with Pompe Disease: A Look           239,740
 LLC                                    at Emerging Therapies and Multidisciplinary
                                        Management Strategies
 
Medical Education Resources Impact     Managing Clinical and Cost Outcomes in Multiple                   75,000
 Education, LLC                         Sclerosis: Expert Insights
 
i3 Health                              Current Trends in the Management of Castration-                   47,530
                                        Resistant Prostate Cancer
 
Oakstone Publishing, LLC Answers in    A Breath of Fresh Air: Exploring Pathophysiology and             340,000
 CME Inc.                               Novel Therapeutic Options to Improve Outcomes in
                                        Moderate-to-Severe Asthma
 
ANA NY, ISONG                          2018 ISONG Congress--Building Connections to Genomic               2,500
                                        Health
 
Affinity CE/PESG LDRTC                 Genetic Rare and Immune Disorders Symposium-GRIDS 2018            50,000
                                        GRIDS 2018 title: Late and Attenuated Presentations
                                        of Lysosomal Storage Disorders
 
UMA MLG, LLC                           A Virtual Reality Experience--Pediatric Atopic                   230,950
                                        Dermatitis: Treatment and Management
 
UMA MLG, LLC                           A Virtual Reality View--Long-term Management of Atopic           449,550
                                        Dermatitis: New and Emerging Targeted Systemic
                                        Therapies
 
UMA Education, Inc. dba Global         Clinical Issues in Atopic Dermatitis: Discussions and            168,203
 Education Group Integritas             Debates on Improving Outcomes for Moderate-to Severe
 Communications                         Disease
 
National Kidney Foundation             Evidence-Based New Insights on the Management of Fabry           145,000
                                        Disease
 
UMA Education Inc., dba Global         Looking Ahead: Optimizing Management Strategies in               393,362
 Education Group Integritas             Moderate-to-Severe Atopic Dermatitis
 Communications
 
Postgraduate Healthcare Education,     Type 1 Gaucher Disease: Optimizing Treatment and                  63,950
 LLC Postgraduate Institute for         Management Approaches
 Medicine (PIM)
 
The France Foundation                  Severe Asthma Science: Endotypes and Precision                   292,680
                                        Medicine Presidential Case Studies
 
UMA Education, Inc dba Global          Clearing the Air in Severe Asthma Management:                    549,981
 Education Group Integritas             Improving Patient Outcomes Through Shared Clinical
 Communications                         Decision Making
 
AKH Inc. Advancing Knowledge in        Masters of Pediatric Dermatology                                  20,000
 Healthcare Tarsus Cardio dba South
 Beach Symposium
 
PRIME Education, LLC                   Atopic Dermatitis Across the Life Cycle: Taking the              199,700
                                        Long View on Diagnostic, Treatment, and Management
                                        Strategies
 
PRIME Education, LLC                   Linking Patients, Providers, and Payers in Coordinated           316,500
                                        Approaches to Severe Asthma Treatment
 
AKH Inc., Advancing Knowledge in       17th Annual South Beach Symposium                                 20,000
 Healthcare Tarsus Cardio
 
PRIME Education, LLC                   Stepping Up Managed Care and Specialty Pharmacy                  499,075
                                        Decision-Making to Support Integration of New
                                        Evidence and Mechanisms in Asthma Treatment
 
Academy of Managed Care Pharmacy       AMCP Specialty Connect--Focus on Gene Therapy                     35,000
 (AMCP)
 
UMA MLG, LLC                           The Unique Role of the Community Pharmacist in the               199,550
                                        Management of Moderate-to-Severe Atopic Dermatitis in
                                        the Pediatric Population
 
Rush University Medical Center Plexus  Applying the Latest Clinical Data and Emerging                    60,000
 Communications                         Therapeutic Approaches in the Management of Prostate
                                        Cancer Throughout the Disease Spectrum
 
Purdue University College of Pharmacy  PeerView Live, ``Unraveling the Complexities of                  109,387
 PVI, PeerView Institute for Medical    Prostate Cancer Management: Focus on Therapeutic
 Education, Inc.                        Decisions for Early Stage Disease and the
                                        Implications for Later Stage Disease''
 
Rush University Medical Center Plexus  Community Uro-Oncology Forums: Understanding the                  80,000
 Communications                         Disease Continuum and Navigating the Evolving
                                        Treatment Paradigms in Prostate Cancer
 
American Health Resources, LLC         Updates in Myeloma Therapeutics: Bone Health,                      8,000
                                        Smoldering Disease, and CAR-T Cells
 
Siyemi Learning                        Action Eczema: Global Atopic Dermatitis Educational              383,320
                                        Resource Center
 
ScientiaCME                            Genetic Disorders: Updates from The 15th Annual World             17,800
                                        Symposium
 
NERGG, Inc.                            NERGG 2018 Annual Meeting                                          6,000
 
UMA MLG, LLC                           The CATALYST Initiative--A 3D View--Targeting                    348,275
                                        Inflammatory Cytokines: Addressing Articular and
                                        Systemic Pathology in Patients with Moderate-to-
                                        Severe Rheumatoid Arthritis
 
University of Nevada, Reno School of   2018 Fall Clinical Dermatology Conferencer and Beyond:           150,000
 Medicine Foundation for Research and   Practical Approaches to Patient Management--Focus on
 Education in Dermatology               Atopic Dermatitis
 
Trustees of Boston University Talem    Talem ACO Summit Series--Atopic Dermatitis: Improving            198,555
 Health, LLC                            Outcomes Through a Patient-Centered Approach
 
Cleveland Clinic Educational           7th Annual Basic & Clinical Immunology for the Busy               15,000
 Foundation                             Clinician
 
University of Nebraska Medical Center  Rural Health Summit Series: Updates in Atopic                    201,343
 The Board of Regents of the            Dermatitis for the Rural Primary Care Physician
 University of Nebraska dba the
 University of Nebraska Medical
 Center
 
International Eczema Council           Atopic Dermatitis Phenotypes and Biomarkers                       11,500
 
Excel Continuing Education             Fabry Disease: Role of the Genetic Counselor in an                81,900
                                        Ever-Changing Landscape; The Role of the Genetic
                                        Counselor in Pompe Disease
 
Specialty Pharma Education Center      Advancing Care in Prostate Cancer: Clinical                       49,750
                                        Understandings & Evolving Treatment and Management
                                        Approaches
 
Massachusetts Eye And Ear Infirmary,   Surgery of the Thyroid and Parathyroid Glands                     15,000
 Department of Otolaryngology
 President and Fellows of Harvard
 College
 
Rush University Medical Center Plexus  VHA UroOncology Clinical Forums ``Advancing Strategies            90,000
 Communications                         in Prostate Cancer: Individualizing Treatment Plans
                                        Based on the Rapidly Evolving Landscape and Disease
                                        Continuum''
 
Physicians' Education Resource, LLC    ``D'' is for Diagnosis: Solving the Mystery of                   100,000
 (PER)                                  Lysosomal Storage Disorders
 
Muscular Dystrophy Association         Medical Education Tactics for the Physician and Care             211,525
                                        Center Community: Hot Topics in NMD Webcast and MDA
                                        Speaker Slides
 
Med-IQ, Inc.                           Bridging the Gap Between Research and Clinical                   245,887
                                        Advances in Gaucher Disease Type 3
 
Medical Education Resources, Inc.      Managing Multiple Sclerosis: A Guide for Specialty                75,000
 Impact Education, LLC                  Pharmacy Professionals
 
Med Learning Group                     A Multiple Sclerosis Virtual Reality Experience:                  50,000
                                        Reaching Diagnosis, Delivering Treatment, and Setting
                                        Goals for Long-Term Success
 
Integrity Continuing Education, Inc.   2019 AAFP State Society CME Meetings and BioDigital              299,000
                                        Human On-demand Simulation Activity--Ensuring Early
                                        Diagnosis and Targeting Treatment to Remission in
                                        Patients with Rheumatoid Arthritis: Recommendations
                                        for Primary Care Clinicians
 
Yale School of Medicine                2019 Update: What's New in the Field of Multiple                  15,000
                                        Sclerosis
 
Annenberg Center for Health Sciences   11th Annual Linda Morgante MS Nurse Leadership Program            45,000
 at Eisenhower Academy for Continued
 Healthcare Learning
 
Physicians' Education Resource, LLC    2019 ACTRIMS: An Interactive, Case-Based Discussion:             212,000
 (PER)                                  Interpreting the Therapeutic Landscape in Multiple
                                        Sclerosis
 
The Medical College of Wisconsin,      29th Annual International Prostate Cancer Update (IPCU            15,000
 Inc. Carden Jennings Publishing Co.,   29)
 Ltd.
 
UMA MLG, LLC                           In Pursuit of the Best Outcomes in Rheumatoid                    194,680
                                        Arthritis: Inhibiting Inflammatory Pathology
 
NJ State Society of Physician          Focus on the Future                                               21,000
 Assistants College of Saint
 Elizabeth
 
Postgraduate Institute for Medicine    Lysomal Storage Disorders--Common Presetations of                 99,885
 Enquiring Minds, LLC                   Uncommon Diseases: Expert Guidance on Early
                                        Identification and Therapeutic Optimization
 
Greenwood Genetic Center               Spring 2019 and Spring 2020 educational program:                  82,003
                                        Enhancing genetic understanding of lysosomal storage
                                        diseases for practicing Physician Assistants (PA) and
                                        PA students
 
ThinkGenetic Foundation                Closing the Genetics Gap: A Lecture for Healthcare                 9,320
                                        Advocates on Lysosomal Storage Diseases Designed to
                                        Increase Access to Genetics Services in Medically
                                        Underserved Parishes of Louisiana
 
National Association for Continuing    Conversations in Primary Care 2019 Live Virtual                   64,000
 Education                              Symposium Series Individualizing Asthma Care:
                                        Addressing Type 2 Inflammation
 
Excel Continuing Education             Newborn Screening for Fabry Disease: What                         86,735
                                        Neonatologists and Pediatricians Needs to Know
 
Excel Continuing Education             Exploring the Genetic Counselor's Role in Gaucher                 42,330
                                        Disease (satellite symposium at NSGC)
 
Mayo Clinic Arizona                    Mayo Clinic 2019 Multiple Sclerosis & Autoimmune                   7,500
                                        Neurology Update
 
UT Southwestern Medical Center         41st Annual Carrell Krusen Neuromuscular Symposium                 5,000
 
Medscape LLC                           Improving Appropriate Use of PCSK9 Inhibitors in                 736,125
                                        Interventional Cardiology: Patient-Centered Care                       Collaboration \3\
                                        Perspectives Post-MI
 
Postgraduate Institute for Medicine    The iQ&A Case-by-Case, PCSK9 Cardiovascular Medicine             488,000
                                        Intelligence zone: from trials to treatment-How Do                     Collaboration \3\
                                        Recent Guidelines and CV Outcome Trials Help Identify
                                        High Risk Patients (Elevated LDL-C, Recent ACS,
                                        Advanced ASCVD, PCI, Statin Intolerance and
                                        Resistance, and Diabetes) Who Are Optimal Candidates
                                        for PCSK9 Inhibitor-Mediated Therapy
----------------------------------------------------------------------------------------------------------------
\1\ Applicant names are provided by the requestor. If applicants apply as a group for a single educational
  activity; all applicants may be not be identified above. The Company funds other educational activities
  (including fellowships and non-physician and patient education); all of which do not appear on this report,
  but appear on other reports on this site.
\2\ ``Funding Amount'' is the amount that the Company funded during Q4, 2018 identified above based upon an
  agreement. Recipients are required to return any unused funds. Information on unused funds returned by the
  applicant on activities are not reported. ``Funding Amount'' does not include funds that may have been
  provided by other affiliated Sanofi Company Entities (e.g., Sanofi Pasteur).
\3\ Collaboration (Shared) Funding--is the full amount of a grant funded under an agreement with Regeneron, some
  or all of which may be shared between the collaborating entities.
\4\ Collaboration (Shared) Funding--is the full amount of a grant funded under an agreement with Lexicon, some
  or all of which may be shared between the collaborating entities.


                            Organization Name
------------------------------------------------------------------------
 
------------------------------------------------------------------------
Hawaii Chapter--National Hemophilia  The Coalition for Hemophilia B
 Foundation
 
Hemophilia of North Carolina         Virginia Hemophilia Foundation
 
Hemophilia Foundation of Greater     West Virginia Chapter National
 Florida                              Hemophilia Foundation
 
The Coalition for Hemophilia B       Brandywine Valley Hemophilia
 Annual Reqests                       Foundation
 
Arizona Hemophilia Association       Hemophilia Association of the
                                      Capital Area
 
Central California Hemophilia        National Hemophilia Foundation,
 Foundation                           Colorado Chapter
 
Hemophilia Foundation of Arkansas,   Hemophilia Foundation of Northern
 Inc.                                 California
 
United Hemophilia Foundation, Inc.   Lone Star Chapter of the National
                                      Hemophilia Foundation
 
Lone Star Chapter of the National    Mississippi Hemophilia Foundation
 Hemophilia Foundation
 
Lone Star Chapter of the National    Lone Star Chapter of the National
 Hemophilia Foundation                Hemophilia Foundation
 
Utah Hemophilia Foundation           Hemophilia Association of the
                                      Capital Area
 
Florida Hemophilia Association       Great Lakes Hemophilia Foundation
 
Bleeding Disorders Alliance          Gateway Hemophilia Association
 Illinois
 
Arizona Hemophilia Association       Tennessee Hemophilia and Bleeding
                                      Disorders Foundation
 
Hemophilia Foundation of Northern    Nebraska Chapter of the National
 California                           Hemophilia Foundation
 
Hemophilia Association of the        Northern Ohio Hemophilia Foundation
 Capital Area
 
Hemophilia Foundation of Southern    Hemophilia Foundation of Southern
 California                           California
 
Hemophilia Alliance of Maine         Bleeding Disorders Association of
                                      Northeastern New York, Inc.
 
Connecticut Hemophilia Society,      Idaho Chapter of the National
 Inc.                                 Hemophilia Foundation
 
Hemophilia Foundation of Minnesota/  Hemophilia Foundation of Michigan
 Dakotas
 
Oklahoma Hemophilia Foundation       Hemophilia and Bleeding Disorders
                                      of Alabama, Inc.
 
Cooley's Anemia Foundation           Oklahoma Hemophilia Foundation
 
Louisiana Hemophilia Foundation      Gateway Hemophilia Association
 
Virginia Hemophilia Foundation       Virginia Hemophilia Foundation
 
Utah Hemophilia Foundation           Alaska Hemophilia Association
 
Nevada Chapter of the National       Utah Hemophilia Foundation
 Hemophilia Foundation
 
Alaska Hemophilia Association        Hemophilia of South Carolina
 
Hemophilia Foundation of Oregon      Tennessee Hemophilia and Bleeding
                                      Disorders Foundation
 
Tennessee Hemophilia and Bleeding    Hemophilia Foundation of Greater
 Disorders Foundation                 Florida
 
Hemophilia of Indiana, Inc.          Hemophilia Foundation of Maryland,
                                      Inc.
 
Hemophilia Foundation of Maryland    Northern Ohio Hemophilia Foundation
 Inc.
 
National Hemophilia Foundation,      National Hemophilia Foundation,
 Colorado Chapter                     Colorado Chapter
 
New England Hemophilia Association   Hemophilia Foundation of Arkansas,
                                      Inc.
 
New England Hemophilia Association   New York City Hemophilia Chapter
 
Hemophilia Foundation of WNY, INC.   The Coalition for Hemophilia B
                                      Woman's Retreat
 
Arizona Hemophilia Association       Hemophilia Foundation of Greater
                                      Florida
 
The Bleeding Disorder Foundation of  National Hemophilia Foundation
 Washington
 
The Hemophilia Association of New    Great Lakes Hemophilia Foundation
 Jersey
 
The Hemophilia Association of New    Texas Central Hemophilia
 Jersey                               Association
 
National Hemophilia Foundation,      Hemophilia Association of San Diego
 Colorado Chapter                     County
 
Kentucky Hemophilia Foundation       Kentucky Hemophilia Foundation
 (KHF)                                (KHF)
 
Kentucky Hemophilia Foundation       Central California Hemophilia
 (KHF)                                Foundation
 
West Virginia Chapter of the         Foundation for Sickle Cell Disease
 National Hemophilia Foundation       Research
 
Federation of American Societies     Gateway Hemophilia Association
 for Experimental Biology
 
Great Lakes Hemophilia Foundation    Hemophilia Foundation of Southern
                                      California
 
United Hemophilia Foundation, Inc.   Florida Hemophilia Association
 
Hemophilia Foundation of Southern    Nevada Chapter of the National
 California                           Hemophilia Foundation
 
Nevada Chapter of the National       Hemophilia of North Carolina
 Hemophilia Foundation
 
Hemophilia of North Carolina         Hemophilia of Indiana, Inc.
 
Hemophilia of Indiana, Inc.          Hemophilia of Indiana, Inc.
 
Hemophilia Association of San Diego  Hawaii Chapter--National Hemophilia
 County                               Foundation
 
Oklahoma Hemophilia Foundation       Disabled Adventure Outfitters
 
National Hemophilia Foundation,      Hawaii Chapter--NHF
 Colorado Chapter
 
Rocky Mountain Hemophilia &          Rocky Mountain Hemophilia &
 Bleeding Disorders Association       Bleeding Disorders Association
 
Virginia Hemophilia Foundation       Hemophilia Association of the
                                      Capital Area
 
Hemophilia Association of the        The Western Pennsylvania Chapter of
 Capital Area                         the National Hemophilia Foundation
 
Lone Star Chapter of the National    Central Ohio Chapter, NHF
 Hemophilia Foundation
 
Bleeding Disorders Alliance          Central California Hemophilia
 Illinois                             Foundation
 
Hemophilia Alliance of Maine         New England Hemophilia Asssociation
 
Alaska Hemophilia Association        FAMOHIO, Inc.
 
FOUNDATION HOPE AND LIFE USA CORP.   National Hemophilia Foundation
 
Midwest Hemophilia Association       Great Lakes Hemophilia Foundation
 
Hemophilia Foundation of WNY, INC.   Utah Hemophilia Foundation
 
Hope for Hemophilia                  Hope for Hemophilia
 
West Virginia Chapter of the         Hemophilia of Iowa, Inc.
 National Hemophilia Foundation
 
New York City Hemophilia Chapter     New England Hemophilia Association
 
Association of Pediatric Hematology  SISTERS AND CAREGIVERS BLEEDING
 Oncology Nurses                      DISORDER NETWORK, INC DBA BLOOD B
 
National Hemophilia Foundation,      Colorado Chapter, National
 Colorado Chapter                     Hemophilia Foundation
 
American Society of Hematology       Hemophilia Association of the
                                      Southern Tier, Inc.
 
Mississippi Hemophilia Foundation    New York City Hemophilia Chapter
 
Comprehensive Health Education       New England Hemophilia Association
 Services
 
Northern Ohio Hemophilia Foundation  Hemophilia Association of the
                                      Capital Area
 
Global Genes                         Mary M. Gooley Hemophilia Center,
                                      Inc.
 
Midwest Hemophilia Association       Hemophilia of South Carolina
 
Arizona Hemophilia Association       Sickle Cell Disease Association of
                                      America, Inc.
 
Hemostasis and Thrombosis Research   Greater Boston Sickle Cell Disease
 Society, Inc.                        Association, Inc.
 
Bleeding Disorders Alliance          Hope for Hemophilia
 Illinois
 
Central Ohio Chapter National        New York City Hemophilia Chapter
 Hemophilia Foundation
 
New York City Hemophilia Chapter     The Hemophilia Association of New
                                      Jersey
 
Arizona Hemophilia Association       Nebraska Chapter of the National
                                      Hemophilia Foundation
 
Nevada Chapter of the National       Sickle Cell Disease Association of
 Hemophilia Foundation                America, Michigan Chapter
 
Hemophilia of South Carolina         Hemophilia of Iowa, Inc.
 
Empowering Women with Bleeding and   Tennessee Hemophilia and Bleeding
 Clotting Disorders (Global Blood     Disorders Foundation
 Disorder Foundation)
 
Hemophilia Foundation of Oregon      The Hemophilia Association of New
                                      Jersey
 
Hemophilia Foundation of Arkansas,   Connecticut Hemophilia Society,
 Inc.                                 Inc.
 
Bleeding Disorders Advocacy Network  National Hemophilia Foundation,
                                      West Virginia Chapter
 
New England Hemophilia Association   Western Pennsylvania Chapter of the
                                      National Hemophilia Foundation
 
Virginia Hemophilia Foundation       Hemophilia Foundation of Greater
                                      Florida
 
Hemophilia Foundation of Greater     National Hemophilia Foundation,
 Florida                              West Virginia Chapter
 
Idaho Chapter of the National        Tri-State Bleeding Disorder
 Hemophilia Foundation                Foundation
 
Northwest Ohio Hemophilia            New York City Hemophilia Chapter
 Foundation
 
Hemophilia Association of the        Hemophilia Foundation of Southern
 Capital Area                         California
 
Hemophilia of North Carolina         Oklahoma Hemophilia Foundation
 
Bleeding Disorders Association of    Louisiana Hemophilia Foundation
 Northeastern New York, Inc.
 
Eastern Pennsylvania Chapter of the  Sangre De Oro, Inc.
 National Hemophilia Foundation
 
National Hemophilia Foundation       Midwest Hemophilia Association
 
United Hemophilia Foundation, Inc.   Texas Central Hemophilia
                                      Association
 
Hemophilia Foundation of Northern    Central Ohio Chapter, NHF
 California
 
The Bleeding Disorder Foundation of  Nebraska Chapter of the National
 Washington                           Hemophilia Foundation
 
The Coalition for Hemophilia B       Northern Ohio Hemophilia Foundation
 
West Virginia Chapter of the         Hemophilia and Bleeding Disorders
 National Hemophilia Foundation       of Alabama, Inc.
 
Academia Medica del Sur, Inc.        Hemophilia Association of New York,
                                      Inc.
 
Texas Central Hemophilia             New York City Hemophilia Chapter
 Association
 
Tri-State Bleeding Disorder          Hemophilia Alliance of Maine
 Foundation
 
Nevada Chapter of the National       FOUNDATION HOPE AND LIFE USA CORP.
 Hemophilia Foundation
 
Central California Hemophilia        American Society of Gene & Cell
 Foundation                           Therapy
 
The Coalition for Hemophilia B       Virginia Hemophilia Foundation
 
Nevada Chapter of the National       Hemophilia Association of the
 Hemophilia Foundation                Capital Area
 
Hemophilia Council of California     Hemophilia Foundation of Maryland,
                                      Inc.
 
Tri-State Bleeding Disorder          Hemophilia Foundation of Southern
 Foundation                           California
 
United Hemophilia Foundation, Inc.   The Bleeding Disorder Foundation of
                                      Washington
 
The Bleeding Disorder Foundation of  Rocky Mountain Hemophilia &
 Washington                           Bleeding Disorders Association
 
New England Hemophilia Association   Arizona Hemophilia Association
 
Hemophilia Foundation of Maryland    Western Pennsylvania Chapter of the
                                      National Hemophilia Foundation
 
Western Pennsylvania Chapter of the  Hemophilia Foundation of Arkansas,
 National Hemophilia Foundation       Inc.
 
Virginia Hemophilia Foundation       Virginia Hemophilia Foundation
 
Hemophilia Foundation of Southern    Hemophilia Council of California
 California
 
Hemophilia Foundation of Maryland,   The Western Pennsylvania Chapter of
 Inc.                                 the National Hemophilia Foundation
 
New England Hemophilia Association   Arizona Hemophilia Association
 
Hawaii Chapter--National Hemophilia  Hawaii Chapter--National Hemophilia
 Foundation                           Foundation
 
Hemophilia Foundation of Southern    Arizona Hemophilia Association
 California
 
Hemophilia of North Carolina         Virginia Hemophilia Foundation
 
Connecticut Hemophilia Society,      Idaho Chapter of the National
 Inc.                                 Hemophilia Foundation
 
Hemophilia Association of New        Bleeding Disorders Alliance of
 Jersey                               North Dakota
 
Hemophilia Foundation of Oregon
------------------------------------------------------------------------


------------------------------------------------------------------------
                                         Payment amount
             Project name                  (in (USD))      Payment date
------------------------------------------------------------------------
Industry Symposium                             $7,500.00       3/13/2018
------------------------------------------------------------------------
The Coalition for Hemophilia B 12th           $20,000.00       3/14/2018
 Annual Symposium
------------------------------------------------------------------------
2018 HNC Walks in Charlotte & Raleigh          $7,500.00       3/14/2018
------------------------------------------------------------------------
Family Weekend                                 $2,500.00       3/16/2018
------------------------------------------------------------------------
Gainesville Clot Trot                          $2,500.00       3/17/2018
------------------------------------------------------------------------
WVNHF Men's and Women's Day                    $3,000.00       3/20/2018
------------------------------------------------------------------------
The Coalition for Hemophilia B 2018            $8,000.00       3/20/2018
 Annual Sponsorship Run
------------------------------------------------------------------------
Big Red Run 2018                               $1,500.00       3/20/2018
------------------------------------------------------------------------
FAME Phoenix and Tucson                        $3,000.00       3/20/2018
------------------------------------------------------------------------
Infusion Classes                               $1,000.00       3/20/2018
------------------------------------------------------------------------
World Hemophilia Day                           $1,000.00       3/22/2018
------------------------------------------------------------------------
Educations Days 2018                           $5,000.00       3/22/2018
------------------------------------------------------------------------
Northwest Arkansas Educational Day             $1,500.00       3/22/2018
------------------------------------------------------------------------
World Hemophilia Day                           $2,500.00       3/23/2018
------------------------------------------------------------------------
Annual Meeting & Family Education              $3,000.00       3/26/2018
 Dinner
------------------------------------------------------------------------
Hill Country Family Education Day              $1,000.00       3/26/2018
------------------------------------------------------------------------
Southeast Texas Family Education Day           $1,000.00       3/26/2018
------------------------------------------------------------------------
Men's Retreat                                  $2,500.00       3/26/2018
------------------------------------------------------------------------
Texas Bleeding Disorders Conference            $6,000.00       3/27/2018
 Exhibit
------------------------------------------------------------------------
Texas Bleeding Disorders Conference           $50,000.00       3/27/2018
------------------------------------------------------------------------
Women and Bleeding Disorders                   $1,500.00       3/27/2018
 Conference
------------------------------------------------------------------------
Family Education Day                           $2,500.00       3/27/2018
------------------------------------------------------------------------
8th Annual Walk in the Jungle                  $5,000.00       3/27/2018
------------------------------------------------------------------------
Family Camp                                    $1,000.00       3/28/2018
------------------------------------------------------------------------
BDAI 2018 Statewide Family Education           $2,500.00       3/28/2018
 Weekend & World
------------------------------------------------------------------------
2018 Bleeding Disorder Walk                    $1,000.00       3/28/2018
------------------------------------------------------------------------
Camp HONOR                                     $1,000.00       3/29/2018
------------------------------------------------------------------------
Be A Factor 5 k                                  $500.00       3/29/2018
------------------------------------------------------------------------
Unite for Bleeding Disorders Health            $2,500.00       3/30/2018
 Fair
------------------------------------------------------------------------
Family Education Weekend                       $3,000.00       3/30/2018
------------------------------------------------------------------------
Family Education Weekend                       $2,000.00        4/3/2018
------------------------------------------------------------------------
Spring Wellness Program                        $1,500.00        4/4/2018
------------------------------------------------------------------------
Teen Leadership Summit                         $1,000.00        4/4/2018
------------------------------------------------------------------------
Family Information Day                         $5,000.00        4/4/2018
------------------------------------------------------------------------
Annual Meeting                                 $5,000.00        4/5/2018
------------------------------------------------------------------------
Unite for Bleeding Disorders Walk              $2,500.00        4/5/2018
------------------------------------------------------------------------
Spring Social                                  $1,500.00        4/5/2018
------------------------------------------------------------------------
Victory for Women                              $2,800.00        4/5/2018
------------------------------------------------------------------------
HFMD Annual Members Meeting                    $1,500.00        4/6/2018
------------------------------------------------------------------------
HFM's 2018 National Conference for           $100,000.00        4/6/2018
 Women with Bleeding Disorders
------------------------------------------------------------------------
OHF Camp Independence                          $4,000.00        4/9/2018
------------------------------------------------------------------------
Camp Clot Not                                  $2,500.00        4/9/2018
------------------------------------------------------------------------
2018 CAF Care Walk                             $7,500.00        4/9/2018
------------------------------------------------------------------------
2018 ``Unite for Bleeding Disorders''          $2,500.00        4/9/2018
 Health Fair and Walk
------------------------------------------------------------------------
2018 Camp Globeclotters                        $2,500.00        4/9/2018
------------------------------------------------------------------------
2018 Camp Notaclotamongus                      $1,250.00       4/10/2018
------------------------------------------------------------------------
Teen/Young Adult Program                      $15,000.00       4/10/2018
------------------------------------------------------------------------
Annual State Educational Meeting               $3,500.00       4/10/2018
------------------------------------------------------------------------
Website ad and direct mailing                  $4,000.00       4/11/2018
------------------------------------------------------------------------
Youth Leadership Weekend 2018                    $500.00       4/11/2018
------------------------------------------------------------------------
Camp Independent Firefly                       $1,000.00       4/11/2018
------------------------------------------------------------------------
Utah Hemophilia Foundation's Family            $2,000.00       4/11/2018
 Resource Fair
------------------------------------------------------------------------
Camp Frozen Chozen                             $3,500.00       4/11/2018
------------------------------------------------------------------------
HELLO- State Annual Meeting and                $2,500.00       4/16/2018
 Educational Conference
------------------------------------------------------------------------
2018 Oregon Unite for Bleeding                 $2,500.00       4/16/2018
 Disorders Walk
------------------------------------------------------------------------
2018 Race for Ian                                $500.00       4/17/2018
------------------------------------------------------------------------
2018 48th Annual Meeting                       $3,000.00       4/17/2018
------------------------------------------------------------------------
17th Annual Family Education Program           $2,800.00       4/19/2018
------------------------------------------------------------------------
Camp Brave Eagle                               $1,500.00       4/19/2018
------------------------------------------------------------------------
Race to Stop the Bleeding                      $4,000.00       4/19/2018
------------------------------------------------------------------------
HFM Family Educational Dinner and              $4,000.00       4/19/2018
 Display Night
------------------------------------------------------------------------
Gears for Good Charity Bike Ride               $1,000.00       4/19/2018
------------------------------------------------------------------------
Colorado Family Camp 2018                      $1,500.00       4/20/2018
------------------------------------------------------------------------
Spanish Program: Greeley                       $1,000.00       4/20/2018
------------------------------------------------------------------------
Family Camp                                    $5,000.00       4/20/2018
------------------------------------------------------------------------
Eighth Annual Center for Bleeding              $1,500.00       4/20/2018
 Disorders Conference
------------------------------------------------------------------------
9th Annual Walk                               $10,000.00       4/20/2018
------------------------------------------------------------------------
NYC Unite for Bleeding Disorders Walk          $5,000.00       4/20/2018
 2018
------------------------------------------------------------------------
New Patient Summer Social                      $1,000.00       4/20/2018
------------------------------------------------------------------------
The Coalition for Hemophilia B Fall           $72,500.00       4/20/2018
 Woman's Retreat
------------------------------------------------------------------------
Community Education Days                       $7,500.00       4/20/2018
------------------------------------------------------------------------
Tampa Superhero Walk For Bleeding              $2,500.00       4/20/2018
 Disorders
------------------------------------------------------------------------
Western Washington Spring Education            $1,500.00       4/20/2018
 Day
------------------------------------------------------------------------
2018 New Jersey Hemophilia Walk                $4,000.00       4/23/2018
------------------------------------------------------------------------
7th Annual Hemophilia Awareness Walk           $2,500.00       4/30/2018
------------------------------------------------------------------------
2018 Wisconsin Bleeding Disorders              $4,000.00        5/1/2018
 Conference
------------------------------------------------------------------------
Hemophilia Association Annual Meeting          $5,000.00       5/15/2018
------------------------------------------------------------------------
2018 TexCen Annual Meeting and Summer          $3,000.00       5/20/2018
 Education Day
------------------------------------------------------------------------
Social Factor: Colorado Spring                 $1,000.00       5/21/2018
------------------------------------------------------------------------
2018 Industry Symposium                        $3,500.00       5/22/2018
------------------------------------------------------------------------
2018 Kentucky Unite for Bleeding               $2,500.00        6/5/2018
 Disorders Walk
------------------------------------------------------------------------
2018 Annual Education Meeting                  $1,750.00        6/5/2018
------------------------------------------------------------------------
2018 KHF Camp Discovery--Summer Camp           $2,000.00        6/5/2018
 Program for Children and Teens
------------------------------------------------------------------------
Unite for Bleeding Disorders Walk              $1,000.00        6/7/2018
------------------------------------------------------------------------
WVNHF Industry Symposium                       $3,000.00        6/7/2018
------------------------------------------------------------------------
12th Annual Sickle Cell Disease                $5,000.00       6/11/2018
 Research and Educational
------------------------------------------------------------------------
FASEB Conference on ``Genome                   $2,000.00       6/13/2018
 Engineering: Cutting-Edge
------------------------------------------------------------------------
2018 Family Education Weekend                  $2,000.00       6/14/2018
------------------------------------------------------------------------
Camp Klotty Pine 2018                          $1,000.00       6/14/2018
------------------------------------------------------------------------
Camp Blood Brothers and Sisters                $2,000.00       6/17/2018
------------------------------------------------------------------------
Family Education Conference                    $5,000.00       6/17/2018
------------------------------------------------------------------------
35th Annual Florida Bleeding Disorders         $6,000.00       6/17/2018
 Conference (Formerly known as the
 ``Family Education Symposium'')
------------------------------------------------------------------------
Familia de Sangre                             $50,000.00       6/18/2018
------------------------------------------------------------------------
Northern Nevada Family Education Day           $1,500.00       6/18/2018
------------------------------------------------------------------------
Unite For Bleeding Disorders                   $1,000.00       6/18/2018
------------------------------------------------------------------------
Union Latina (Latin Union) Educational         $2,500.00       6/18/2018
 Retreat
------------------------------------------------------------------------
Men's Educational Retreat                      $1,500.00       6/18/2018
------------------------------------------------------------------------
2018 Hemophilia of Indiana Annual              $4,000.00       6/19/2018
 Meeting
------------------------------------------------------------------------
2018 Unite For Bleeding Disorders Walk         $3,500.00       6/19/2018
------------------------------------------------------------------------
Doug Thompson Teen Leadership Camp             $1,500.00       6/19/2018
------------------------------------------------------------------------
2018 Teen Camp                                 $2,000.00       6/20/2018
------------------------------------------------------------------------
Hawaii Teen Summit                             $7,500.00       6/20/2018
------------------------------------------------------------------------
OHF Annual Meeting 2018                        $3,500.00       6/20/2018
------------------------------------------------------------------------
Teen Adventure Camp                            $2,500.00       6/20/2018
------------------------------------------------------------------------
Mile High Summer Camp 2018                     $1,000.00       6/20/2018
------------------------------------------------------------------------
Koko Ohana Family Camp                         $2,500.00       6/20/2018
------------------------------------------------------------------------
RMHBDA Walk for Bleeding Disorders             $1,500.00       6/21/2018
------------------------------------------------------------------------
RMHBDA BIG SKY FAMILY CAMP                     $1,000.00       6/21/2018
------------------------------------------------------------------------
Camp Youngblood--Summer Camp                   $1,000.00       6/21/2018
------------------------------------------------------------------------
Summer Camp                                    $1,000.00       6/21/2018
------------------------------------------------------------------------
HACA Fall Festival and Walk                    $7,500.00       6/21/2018
------------------------------------------------------------------------
Western Pennsylvania Walk, Run, and            $2,000.00       6/21/2018
 Cornhole Tournament
------------------------------------------------------------------------
Unite for Bleeding Disorders Walk              $3,000.00       6/22/2018
------------------------------------------------------------------------
COC-New Patient Orientstion                    $1,750.00       6/22/2018
------------------------------------------------------------------------
BDAI 2018 Unite Walk for Bleeding              $2,500.00       6/25/2018
 Disorders Sponsorship
------------------------------------------------------------------------
Family Education Day                           $5,500.00       6/26/2018
------------------------------------------------------------------------
Hike4HAM                                       $2,500.00       6/27/2018
------------------------------------------------------------------------
Women's Retreat                                $2,000.00       6/27/2018
------------------------------------------------------------------------
Alaska Bleeding Disorder Walk--Exhibit         $1,750.00       6/27/2018
------------------------------------------------------------------------
FAMOHIO Annual Meeting and Educational        $12,500.00       6/27/2018
 Symposium
------------------------------------------------------------------------
Back to School Educational Event               $2,500.00       6/28/2018
------------------------------------------------------------------------
NHF 2018 Bleeding Disorders Conference       $237,000.00       6/29/2018
 Sponsorships
------------------------------------------------------------------------
MHA UNITE for Bleeding Disorders Walk-         $2,500.00        7/2/2018
 a-Thon
------------------------------------------------------------------------
2018 Wisconsin Unite for Bleeding              $5,000.00        7/2/2018
 Disorders Walk
------------------------------------------------------------------------
``In my Blood'' Bleeding Disorders             $2,000.00        7/2/2018
 Awareness Walk
------------------------------------------------------------------------
Camp Valor 2018                                $6,000.00        7/2/2018
------------------------------------------------------------------------
Superhero Run/Walk--Covington, LA              $5,000.00        7/3/2018
------------------------------------------------------------------------
Superhero HOPE Run/Walk--Wichita, KS           $5,000.00        7/3/2018
------------------------------------------------------------------------
WVNHF Family Camp                              $3,000.00        7/5/2018
------------------------------------------------------------------------
Annual Meeting                                 $1,500.00        7/5/2018
------------------------------------------------------------------------
Kids Day Camp                                  $7,000.00        7/6/2018
------------------------------------------------------------------------
BLeaders Teen Retreat                          $5,000.00       7/15/2018
------------------------------------------------------------------------
BITS AND PIECES OF Pediatric                   $1,000.00       7/16/2018
 Hematology, Oncology & BM
------------------------------------------------------------------------
BBBDN Back to School Educating for             $5,000.00       7/16/2018
 Success
------------------------------------------------------------------------
Western Slope Social Factor                    $1,000.00       7/17/2018
------------------------------------------------------------------------
Colorado Unite for Bleeding Disorders          $1,500.00       7/17/2018
 Walk
------------------------------------------------------------------------
ASH Corporate Friends                         $35,000.00       7/17/2018
------------------------------------------------------------------------
Annual BDAST 2018 Hike Fundraiser              $3,000.00       7/17/2018
------------------------------------------------------------------------
Family Retreat                                 $4,000.00       7/17/2018
------------------------------------------------------------------------
NYCHC 2018 Women's Retreat                    $10,000.00       7/23/2018
------------------------------------------------------------------------
National LadyBugs Womens Summit               $50,000.00        8/2/2018
------------------------------------------------------------------------
Hispanic Heritage Symposium                    $3,500.00        8/2/2018
------------------------------------------------------------------------
UNITE for Bleeding Disorders Walk              $2,500.00        8/2/2018
------------------------------------------------------------------------
Women's Retreat                                $2,000.00        8/2/2018
------------------------------------------------------------------------
2018 Patient Advocacy Summit                  $33,000.00        8/7/2018
------------------------------------------------------------------------
2018 Finger Lakes Triathlon                    $5,000.00        8/7/2018
------------------------------------------------------------------------
MHA Family Education Weekend--                 $2,000.00        8/8/2018
 Connecting the Bleeding
------------------------------------------------------------------------
Educational Family Camp and Adult              $3,000.00       8/10/2018
 Retreat
------------------------------------------------------------------------
NACCHO 2019                                  $180,000.00       8/13/2018
------------------------------------------------------------------------
46th Annual SCDAA National Convention         $25,000.00       8/14/2018
------------------------------------------------------------------------
HTRS Corporate Colleague--Sustaining          $10,000.00       8/16/2018
 Member
------------------------------------------------------------------------
Walk for Sickle Cell Disease                   $5,000.00       8/20/2018
------------------------------------------------------------------------
Community Liaison Project                      $5,000.00       8/22/2018
------------------------------------------------------------------------
2018 HOPE Conference                          $15,000.00       8/23/2018
------------------------------------------------------------------------
Unite for Bleeding Disorders 5K                $2,500.00       8/28/2018
------------------------------------------------------------------------
TORCH Teen Retreat                             $7,000.00       8/29/2018
------------------------------------------------------------------------
Bilingual Back to School Event                 $5,000.00       8/29/2018
------------------------------------------------------------------------
Hemophilia Association of New Jersey           $2,500.00       8/29/2018
 (HANJ) Fall Education
------------------------------------------------------------------------
Annual Statewide Meeting                      $10,000.00       8/29/2018
------------------------------------------------------------------------
Unite for Bleeding Disorder Walk               $1,000.00        9/4/2018
------------------------------------------------------------------------
Fall Fam Jam                                   $1,000.00        9/5/2018
------------------------------------------------------------------------
Sickle CELLebration                            $3,000.00        9/5/2018
------------------------------------------------------------------------
The Turkey Trot 5k Walk for Hemophilia         $2,500.00        9/6/2018
 and Bleeding Disorders
------------------------------------------------------------------------
Unite for Bleeding Disorder Walk               $1,500.00        9/6/2018
------------------------------------------------------------------------
Empowering Women with Bleeding and             $3,500.00        9/7/2018
 Clotting Disorders
------------------------------------------------------------------------
Blazin for Bleeders 5k/walk                    $1,000.00        9/7/2018
------------------------------------------------------------------------
2018 HFO Insurance Forum                       $3,000.00        9/7/2018
------------------------------------------------------------------------
2018 PACT Workshop                            $15,000.00        9/8/2018
------------------------------------------------------------------------
2018 Family Retreat/Annual Meeting             $3,500.00       9/10/2018
------------------------------------------------------------------------
Annual Meeting                                 $1,500.00       9/10/2018
------------------------------------------------------------------------
2018 BDAN Fall Family Retreat                  $2,500.00       9/10/2018
------------------------------------------------------------------------
Spokes Men for Bleeders                          $500.00       9/11/2018
------------------------------------------------------------------------
Fall Fest                                      $5,000.00       9/11/2018
------------------------------------------------------------------------
WPCNHF'S Erie Educational Event                $2,000.00       9/11/2018
------------------------------------------------------------------------
Unite for Bleeding Disorders Walk              $5,000.00       9/11/2018
------------------------------------------------------------------------
Orlando Creepy Crawl 5K and Vampire            $3,000.00       9/11/2018
 Mile
------------------------------------------------------------------------
Jacksonville Creepy Crawl 5K and               $3,000.00       9/11/2018
 Vampire Mile
------------------------------------------------------------------------
Unite for Bleeding Disorders--Annual           $2,500.00       9/17/2018
 Walk
------------------------------------------------------------------------
Unite for Bleeding Disorders Walk              $1,000.00       9/17/2018
------------------------------------------------------------------------
TSBDF Annual Meeting                           $1,500.00       9/17/2018
------------------------------------------------------------------------
Unite for Bleeding Disorders Walk              $1,000.00       9/17/2018
------------------------------------------------------------------------
Latino Retreat                                $10,000.00       9/17/2018
------------------------------------------------------------------------
Spanish-Language Education Event               $1,500.00       9/17/2018
------------------------------------------------------------------------
Inaugural Health Fair                          $2,500.00       9/18/2018
------------------------------------------------------------------------
2018 Adult Retreat                             $1,500.00       9/19/2018
------------------------------------------------------------------------
OHF Family Education Retreat                   $1,000.00       9/20/2018
------------------------------------------------------------------------
Annual Meeting                                 $2,000.00       9/21/2018
------------------------------------------------------------------------
42nd Annual Meeting and Educational            $5,500.00       9/26/2018
 Symposium
------------------------------------------------------------------------
Trick or Trot Family Walk                      $3,000.00       9/26/2018
------------------------------------------------------------------------
Patient and Family Education Weekend           $2,500.00       10/5/2018
------------------------------------------------------------------------
2018 Bleeding Disorders Conference            $35,000.00       10/8/2018
 Final Night Event
------------------------------------------------------------------------
Wichita Education Day                          $1,500.00       10/9/2018
------------------------------------------------------------------------
Winter Education Meeting and Holiday           $3,500.00       10/9/2018
 Festival
------------------------------------------------------------------------
8th Annual Unite for Bleeding                  $2,500.00       10/9/2018
 Disorders Walk and Fun Race
------------------------------------------------------------------------
Family Education Day                           $2,500.00      10/11/2018
------------------------------------------------------------------------
COC-Education Retreat                          $3,250.00      10/11/2018
------------------------------------------------------------------------
Eastern Washington Annual Meeting 2018         $1,500.00      10/11/2018
------------------------------------------------------------------------
Nebraska Industry Symposium                    $5,000.00      10/16/2018
------------------------------------------------------------------------
The Coalition for Hemophilia B                 $3,000.00      10/16/2018
 Meetings on the Road
------------------------------------------------------------------------
NOHF Annual Education Meeting                  $5,500.00      10/16/2018
------------------------------------------------------------------------
Annual Meeting                                 $3,000.00      10/17/2018
------------------------------------------------------------------------
Camp Harvest                                   $6,000.00      10/18/2018
------------------------------------------------------------------------
Issues and Challenges in the                   $2,500.00      10/22/2018
 Management of Hemophilia
------------------------------------------------------------------------
Steven Margolies, MD Family                    $6,000.00      10/22/2018
 Educational Conference
------------------------------------------------------------------------
2018 TexCen Chapter Winter Education           $3,000.00       11/1/2018
 Day
------------------------------------------------------------------------
NYCHC Annual Education Day                     $7,500.00       11/2/2018
------------------------------------------------------------------------
TSBDF Education Dinner                         $2,000.00       11/5/2018
------------------------------------------------------------------------
Winterfest                                     $1,500.00       11/6/2018
------------------------------------------------------------------------
Annual Family Conference                       $2,250.00      11/19/2018
------------------------------------------------------------------------
Holiday Educational Program                    $2,000.00       12/6/2018
------------------------------------------------------------------------
College and Career Fair                        $1,500.00      12/11/2018
------------------------------------------------------------------------
ASGCT Patient Education Videos                 $5,000.00      12/13/2018
------------------------------------------------------------------------
The Coalition for Hemophilia B Patient        $10,000.00      12/18/2018
 Survey
------------------------------------------------------------------------
Advocacy Training                              $2,500.00      12/18/2018
------------------------------------------------------------------------
Grassroots Advocacy Project                    $5,000.00      12/19/2018
------------------------------------------------------------------------
State Advocacy Training                          $500.00        1/3/2019
------------------------------------------------------------------------
Annual Silver-level Corporate                 $15,000.00        1/4/2019
 Sponsorship
------------------------------------------------------------------------
Annual Meeting and Family Educational         $10,000.00        1/7/2019
 Dinner
------------------------------------------------------------------------
TSBDF Winter Program-Journey Around            $1,500.00        1/7/2019
 the World
------------------------------------------------------------------------
4th Annual Industry Forum                      $5,000.00       1/11/2019
------------------------------------------------------------------------
Advocacy Education and Training                $5,000.00       1/15/2019
 Seminar
------------------------------------------------------------------------
Latino Group Weekend 2019                      $1,500.00       1/16/2019
------------------------------------------------------------------------
Winter Education Day 2019                      $1,500.00       1/16/2019
------------------------------------------------------------------------
RMHBDA EDUCATION WEEKEND AND ANNUAL            $2,000.00       1/16/2019
 MEETING
------------------------------------------------------------------------
New England Hemophilia Association             $1,500.00       1/16/2019
 Winter Camp
------------------------------------------------------------------------
Purpose Driven Leadership Program              $2,500.00       1/16/2019
------------------------------------------------------------------------
Maryland Advocacy Days                         $5,000.00       1/21/2019
------------------------------------------------------------------------
WPCNHF's New Parent Network                    $4,000.00       1/21/2019
------------------------------------------------------------------------
WPCNHF's Semi-Annual Education Weekend         $5,000.00       1/21/2019
------------------------------------------------------------------------
Men In Action/Infusing Love Group's            $1,500.00       1/21/2019
 Valentine Event
------------------------------------------------------------------------
Medial Symposium                               $5,000.00       1/21/2019
------------------------------------------------------------------------
Women's Retreat                                $5,000.00       1/21/2019
------------------------------------------------------------------------
emPOWERment Forum                              $2,500.00       1/22/2019
------------------------------------------------------------------------
2018 Corporate Program Sponsorship--           $1,875.00        2/4/2019
 Silver
------------------------------------------------------------------------
Four Bioverativ Branded Educational            $1,250.00        2/4/2019
 Dinners
------------------------------------------------------------------------
WPCNHF's New Parent Network                    $1,000.00        2/4/2019
------------------------------------------------------------------------
Consumer Medical Symposium                     $3,000.00       2/12/2019
------------------------------------------------------------------------
Zoo Walk 2019                                  $4,000.00       2/12/2019
------------------------------------------------------------------------
Hawaii Future Leaders                          $2,500.00       2/13/2019
------------------------------------------------------------------------
Hawaii Ohana Education Weekend 2019            $7,500.00       2/13/2019
------------------------------------------------------------------------
Women's Retreat                                $3,500.00       2/13/2019
------------------------------------------------------------------------
Bleeding Disorder Awareness Kick Off           $1,500.00       2/13/2019
------------------------------------------------------------------------
2019 Annual Meeting                            $2,000.00       2/13/2019
------------------------------------------------------------------------
Teen--Young Adult Program                     $15,000.00       2/13/2019
------------------------------------------------------------------------
15th Annual CHS Alpine Walk                    $2,000.00       2/20/2019
------------------------------------------------------------------------
Victory for Women                              $2,800.00        3/7/2019
------------------------------------------------------------------------
Winter Membership Gathering                    $5,000.00        3/7/2019
------------------------------------------------------------------------
2019 Annual Meeting                            $3,000.00       3/13/2019
------------------------------------------------------------------------
YETI--Youth Effectively Transitioning          $5,000.00       3/18/2019
 to Independence
------------------------------------------------------------------------


                             2015 SANOFI US
------------------------------------------------------------------------
      Legal Name                 Project Title            Payment Amount
------------------------------------------------------------------------
A R M S Inc.            Homecoming & Project Little            $5,000.00
                         Soldier
 
Academy of Managed      Improving patient outcomes and        $45,000.00
 Care Pharmacy           management of hyperlipidem
 
ACS Organic Chemistry   Graduate Research Symposium            $1,000.00
 Division
 
AHIP Foundation         Executive Leadership Program          $55,000.00
 
Alabama Kidney          2015 Huntsville Kidney Walk            $1,000.00
 Foundation
 
Alabama Kidney          2015 Birmingham Kidney Walk            $1,000.00
 Foundation
 
Alabama Kidney          Dothan Kidney Walk                     $1,000.00
 Foundation
 
Albany American         Saratoga Springs Tour de Cure          $5,000.00
 Diabetes Association
 
ALL IN TOGETHER         All in Together Campaign:             $37,500.00
 CAMPAIGN INC.           Advancing and Empowering Women
 
Allergy & Asthma        US Anaphylaxis Summit                 $30,000.00
 Network Mothers of
 Asthmatics
 
Allergy & Asthma        AAP Anaphylaxis Champions            $100,000.00
 Network Mothers of      Program
 Asthmatics
 
Allergy & Asthma        Allergy & Asthma Day Capitol          $50,000.00
 Network Mothers of      Hill 2015
 Asthmatics
 
Alliance For A          Alliance for a Healthier              $25,000.00
 Healthier Generation    Generation
 Inc.
 
Alliance for Aging      2015 Aging in Motion Coalition        $15,000.00
 Research
 
Amerian Diabetes        American Diabetes Association          $2,500.00
 Association             Diabetes Health and Wellness
                         Expo
 
American Academy of     American Academy of Pediatrics        $35,000.00
 Pediatrics-Key Cards    Key Card Sponsorship
 
AMERICAN ASSOCIATION    2015 AACR Annual Meeting MICR         $10,000.00
 FOR CANCER RESEARCH     Networking and Resource Center
 
AMERICAN ASSOCIATION    2015 AACR Network Hubs                $25,000.00
 FOR CANCER RESEARCH     Sponsorship
 
American Cancer         ACS CAN Seattle Research               $2,500.00
 Society                 Breakfast and ACS CAN advocacy
                         activities
 
American Cancer         ACS CAN CA Research Events and         $5,000.00
 Society                 ACS CAN advocacy activities
 
American Cancer         ACS CAN's advocacy activities          $1,500.00
 Society                 in Arkansas and nationwide
 
American Cancer         ACS CAN Virginia Research              $1,000.00
 Society                 Breakfast and advocacy
                         activities
 
American Cancer         ACS CAN's advocacy activities          $1,000.00
 Society                 in Louisiana and nationwide
 
American Cancer         ACS CAN Mississippi Health             $1,000.00
 Society                 Forum and ACS CAN advocacy
                         activities
 
American Cancer         ACS CAN Iowa Research Event and        $2,000.00
 Society                 ACS CAN advocacy activities
 
American Cancer         2015 Minnesota Policy Breakfast        $1,000.00
 Society                 and ACS CAN advocacy
                         activities
 
American Cancer         2015 Oklahoma Policy Forums              $750.00
 Society
 
American Cancer         2015 Pennsylvania Advocacy             $1,000.00
 Society                 Event
 
American Cancer         2015 Maryland Advocacy                 $1,000.00
 Society                 Breakfast
 
American Cancer         Gemson Awards                          $2,500.00
 Society
 
American Cancer         Nationwide Hope Lodge                 $25,000.00
 Society Inc.            Partnership
 
American Chemical       Division of Medicinal Chemistry        $2,500.00
 Society Division of     Program 250th ACS national me
 Medicinal Chemistry
 
American College of     American College of Allergy,          $53,000.00
 Allergy, Asthma &       Asthma & Immunology FIT Bowl
 Immunology-FIT Bowl
 
American College of     2015 Patient Engagement               $25,000.00
 Cardiology              Pavilion
 
American College of     Sanofi/Regeneron Meeting              $10,412.60
 Cardiology
 
American College of     Moving to the Quadruple Aim:         $280,369.00
 Physicians, Inc.        ACP Quality Connect: Diabetes
 
American Diabetes       Step Out: Walk to Stop Diabetes        $5,000.00
 Assocation
 
American Diabetes       Central Iowa Tour de Cure              $5,000.00
 Association
 
American Diabetes       Tour de Cure Southeast                 $1,500.00
 Association             Wisconsin (Grafton)
 
American Diabetes       Tour de Cure Madison                   $1,500.00
 Association
 
American Diabetes       2015 American Diabetes                 $2,000.00
 Association             Association--WI Gala
 
American Diabetes       Father of the Year/Camp Sugar          $2,000.00
 Association             Falls
 
American Diabetes       Father of the Year Awards              $5,000.00
 Association
 
American Diabetes       Stop Diabetes Through Advocacy         $2,000.00
 Association             Workshop
 
American Diabetes       Boston Step Out Walk to STOP           $5,000.00
 Association             Diabetes
 
American Diabetes       Central MA Step Out Walk to            $5,000.00
 Association             STOP Diabetes
 
American Diabetes       2015 Kiss a Pig Gala                   $2,500.00
 Association
 
American Diabetes       2015 Rochester Tour de Cure            $2,500.00
 Association
 
American Diabetes       Step Out: Walk to Stop Diabetes        $5,000.00
 Association
 
American Diabetes       Portland Father of the Year            $2,500.00
 Association             Awards Dinner
 
American Diabetes       Jim Hansen, MD Memorial                $3,500.00
 Association             Symposium Series
 
American Diabetes       St. Louis Tour de Cure                   $500.00
 Association
 
American Diabetes       Diabetes Awareness and                $50,000.00
 Association             Intervention--via Step Out:
                         Walk to St
 
American Diabetes       2015 World Diabetes Day                $5,000.00
 Association
 
American Diabetes       75th Anniversary & Awards             $50,000.00
 Association             Celebration
 
American Diabetes       Step Out Walk to STOP Diabetes         $2,500.00
 Association
 
American Diabetes       American Diabetes Expo--Exhibit/      $57,000.00
 Association Expo-       Speaker/Booth Signage/Program
 Exhibit/Speaker/
 BoothSignage/Program
 
AMERICAN DIABETES       Diabetes Hospitality Days: Stop       $75,000.00
 ASSOCIATION INC.        Diabetes In Boston
 
AMERICAN DIABETES       2015 Pathways to Stop Diabetes     $2,500,000.00
 ASSOCIATION INC.
 
AMERICAN DIABETES       Step Out: Walk to Stop Diabetes        $5,000.00
 ASSOCIATION INC.
 
AMERICAN DIABETES       Step Out: Walk to Stop Diabetes        $2,500.00
 ASSOCIATION INC.
 
AMERICAN DIABETES       Father of the Year Awards Gala         $5,000.00
 ASSOCIATION INC.
 
American Diabetes       2015 Tour de Cure                      $5,000.00
 Association, Indiana
 Indiana
 
American Diabetes       ADA Indiana's Josiah Kirby            $15,000.00
 Association, Indiana    Lilly Sr. Distinguished
                         Service Award
 
American Diabetes       Father of the Year Gala                $5,000.00
 Associaton
 
American Heart          AMERICAN HEART ASSOCIATION--          $75,000.00
 Association             MOBILE APP
 
American Heart          2015 Walking Challenge               $100,000.00
 Association
 
American Heart          American Heart Association            $50,000.00
 Association             Advertising Space (Key Cards)
 
American Heart          2015 Heart Innovation Forum           $15,000.00
 Association
 
American National Red   2015-2016 General Blood               $25,000.00
 Cross                   Services Support and High
                         School Sc
 
American Pharmacists    Emerging Insulins                     $79,000.00
 Association
 
American Society for    Second Regional Bone Marrow           $12,700.00
 Blood and Marrow        Transplant conference for
 Transplantation         Nurses
 
American Society of     2015 ASN Abstract CD                  $80,000.00
 Nephrology              Sponsorship
 
American Society of     2015 Sponsorship Opportunities        $50,000.00
 Transplantation
 
Americares Foundation   US Disaster Assistance                $10,000.00
 Inc.
 
America's Health        CMO Roundtable                        $45,000.00
 Insurance Plans
 
APhA Foundation         Primary Care and Patient             $249,550.00
                         Empowerment through Diabetes
                         Patie
 
Arizona Diabetes        Diabetes: A Prescription for           $5,000.00
 Foundation              Care
 
Arrow Lake Foundation   Arrow Lake Foundation                 $50,000.00
                         Activities Plan
 
Arthritis Foundation    Research Update Events                $10,000.00
 Northeast Region,
 Inc.
 
Arthritis Foundation    Advocacy Program and Advocacy         $15,000.00
 Northeast Region,       Training Series
 Inc.
 
Association for         IQ/AAALAC International Global         $5,000.00
 Assessment and          3Rs Awards
 Accreditation of
 Laboratory Animal Ca
 
Association of          32 National Oncology Conference       $50,000.00
 Community Cancer
 Centers
 
Association of          2015 Membership Dues                   $6,250.00
 Corporate
 Contributions
 Professionals
 
Asthma & Allergy        Advocacy Day                           $1,000.00
 Foundation of
 America, St. Louis
 Chapter
 
Asthma & Allergy        Allertrain Master Trainer              $1,500.00
 Foundation of           Program
 America, St. Louis
 Chapter
 
Asthma and Allergy      2015 KFA Anaphylaxis Patient          $33,000.00
 Foundation of America   Education
 
Asthma and Allergy      2015 Anaphylaxis Awareness           $250,000.00
 Foundation of America   Campaign
 
ASTS Foundation         ASTS Program Support                  $75,000.00
 
Autoimmune Advocacy     Living with Autoimmunity--3            $2,500.00
 Alliance                separate events
 
Bay Area Association    Help! I Just Learned I have            $1,200.00
 of Kidney Patients      Chronic Kidney Disease! What
                         do I do?
 
Bay Area Bioscience     CALBIO 2015                           $10,000.00
 Association
 
Baylor Health Care      STEEEP Academy Lectureship           $135,000.00
 System Foundation       Series
 
Be The Match            Quick Reference Guidelines--          $90,000.00
 Foundation              Transplant Consultation and
                         Post-Transplant
 
BHCAG FOUNDATION        MNBTE Recognition Event                $5,000.00
 
Bill, Hillary, and      Program Support--CHMI                $100,000.00
 Chelsea Clinton
 Foundation
 
Bill, Hilary, and       National Health Transformation        $50,000.00
 Chelsea Clinton
 Foundation
 
Biocom                  Global Life Science Partnering        $10,000.00
                         Conference
 
BIONJ INC.              Bio NJ Sponsorship event              $10,000.00
 
BIONJ INC.              BIONJ INC. BioPartnering               $3,000.00
 
BIONJ INC.              CEO Summit                             $7,500.00
 
Blood and Marrow        Survivorship Symposium Pre-Plan        $5,000.00
 Transplant
 Information Network
 
Blood and Marrow        Ask the Multiple Myeloma Expert        $7,500.00
 Transplant
 Information Network
 
Blood and Marrow        Transplant 101: An introduction        $7,500.00
 Transplant              to hematopoietic cell
 Information Network     transplant
 
Blood and Marrow        Caregiver 101: The Role of             $7,500.00
 Transplant              Caregiver in Support of Bone
 Information Network     Marrow
 
Blood and Marrow        Enhancing the Power of Peer            $7,500.00
 Transplant              Support
 Information Network
 
Blood and Marrow        BMT InfoNet Web Site Redesign--       $75,000.00
 Transplant              Phase 1
 Information Network
 
Bringing Hope Home      General Operating Support             $10,000.00
 Inc.
 
Buffalo American        Buffalo Niagara Tour de Cure           $5,000.00
 Diabetes Association
 
Cambridgeport           2015 Summer Programs at                $5,000.00
 Neighborhood            Magazine Beach Park
 Association, Inc.
 
Camp Nejeda Foundation  Helping Children with type 1          $20,000.00
                         diabetes live happier,
                         healthier lives
 
Cancer Resource         Boston Prostate Cancer Walk Run        $5,000.00
 Foundation
 
Cancer Support          Celebration of Hope: A Free,           $5,000.00
 Community Greater       Full-Day, Educational and
 Philadelphia            Inspirational
 
Cardio Renal Society    Path to Wellness National Pilot      $100,000.00
 of America
 
Center for Healthcare   Diversity, Inclusion, & Life           $9,500.00
 Innovation              Sciences Symposium
 
Central New Jersey      Leaders of Tomorrow (LOT)             $10,000.00
 Chapter Of The          Program
 National Black Mba
 Association
 
CEO Roundtable On       Project Data Sphere initiative     $1,000,000.00
 Cancer, Inc.
 
Chicago Hispanic        Vive tu Vida/Get Up! Get               $1,000.00
 Health Coalition        Moving! Health and Wellness
                         Fair
 
Children with Diabetes  Platinum Sponsorship--Children        $75,000.00
                         With Diabetes--Friends for
                         Life
 
Children with Diabetes  Gold Level sponsorship of the        $100,000.00
                         Children with Diabetes Friends
                         for Life
 
Childrens Inn At NIH    Sanofi US Legacy Endowment Fund    $1,000,000.00
 Inc.                    at The Children's Inn at NIH
 
Children's Medical      Food Allergy Camp                      $5,000.00
 Center Foundation
 
Chordoma Foundation     New York Regional Chordoma             $2,500.00
                         Community Conference
 
Chris4Life Colon        5th Annual Blue Hope Bash              $3,000.00
 Cancer Foundation
 
Christ the King Prep    Corporate Work Study Program          $57,000.00
 
Cleveland Clinic        Advances in Organ                    $134,276.00
                         Transplantation--Annual
                         Fellows Conference
 
CNY American Diabetes   2015 CNY Tour de Cure                  $4,000.00
 Association
 
Coastal Area Health     Community Health Worker Core          $25,000.00
 Education Center Inc.   Consensus (C3) Project
 
Colon Cancer Alliance   Blue Star Concert                      $1,000.00
 
Committee Encouraging   2015 Membership Dues                  $15,000.00
 Corporate
 Philanthropy
 
Community Oncology      2015 Community Oncology Payer         $25,000.00
 Alliance                Exchange Summit III Oncology
 
Conquer Cancer Fdn Of   Conquer Cancer Foundation             $50,000.00
 The American Society    General Mission Support
 Of Clinical Oncology
 
Council on Foundations  2015 Membership Dues                  $15,000.00
 
CT Coalition for Organ  Premier Charity of the Hartford        $1,500.00
 and Tissue Donation,    Marathon
 dba, Donate Life
 Connect
 
Dallas Fort Worth       DFWBGH 11th Annual Benefits            $5,000.00
 Business Group on       Forum
 Health
 
DaVita Village Trust    2015 Tour DaVita                       $2,500.00
 
Deirdre O Brien Child   Clinical Counseling Program           $10,000.00
 Advocacy Center Inc.
 
Diabetes Care and       DCE NewsFlash and 2 e-Blasts          $21,500.00
 Education with the
 Academy of Nutrition
 and Diete
 
Diabetes Education and  2015 Industry Partners Advisory       $15,000.00
 Camping Association     Council (IPAC)
 
Diabetes Foundation     Dancing for Diabetes Awards           $10,000.00
 Inc.                    Dinner
 
Diabetes Hands          Online Community for People           $12,500.00
 Foundation              with Diabetes
 
Diabetes Hands          DHF--Hero Sponsorship                 $25,000.00
 Foundation
 
DiabetesSisters         2015 DiabetesSisters' PODS            $20,000.00
                         Meetup Program
 
Diplomacy Matters       Spotlighting Humanitarian              $2,500.00
 Institute               Innovation & Patents for
                         Humanity
 
Direct Relief           Auvi-Q epinephrine injections        $75,000.00
                         for students throughout
                         California
 
Direct Relief           U.S. Hurricane/All Hazards            $10,000.00
                         preparedness Program
 
Employers Health        Employer Health 2015 Annual            $6,500.00
 Coalition, Inc.         Symposium
 
Epilepsy Foundation of  Parent Advocacy toolkit                $8,000.00
 NC
 
Federal Circuit Bar     Global Series: 2015 Shanghai          $10,000.00
 Association             Conference
 Charitable and
 Educational Fund
 
Federation of Clinical  FOCIS 2015 Annual Meeting             $14,500.00
 Immunology Societies
 
Fight Colorectal        Patient Resource Guide for             $5,000.00
 Cancer                  Stage III and IV
 
Finger Lakes American   2015 Finger Lakes Tour de Cure         $4,000.00
 Diabetes Association
 
Florida Health Care     Seeking Value in Cancer Care           $5,000.00
 Coalition
 
Florida Health Care     Health Care Purchasers as              $7,500.00
 Coalition               Consumers: Smart Shopping for
                         Health Care
 
Food Allergy &          FAACT Education Programs             $150,000.00
 Anaphylaxis
 Connection Team
 
Food Allergy Research   FARE National Food Allergy            $25,000.00
 Education               Conference
 
Food Allergy Research   FARE Teen Summit                      $25,000.00
 Education
 
Food Allergy Research   THE FOOD ALLERGY BALL                 $25,000.00
 Education
 
Food Allergy Research   FAREWalk for Food Allergies          $200,000.00
 Education
 
Food Bank of Somerset   Back Pack Program                      $5,000.00
 County Inc.
 
Foundation for          FBR Educational Programs--Bench       $10,000.00
 Biomedical Research     to Bedside, Social Ambassadors
 
Foundation For Prader   Multiple Projects                      $1,000.00
 Willi Research
 
Fundacion Centro        Diabetes Summer Camp 2015             $10,000.00
 Pediatrico de
 Diabetes
 
Fundacion Centro        XIV Gala                               $3,500.00
 Pediatrico de
 Diabetes
 
Fundacion Centro        8th World Diabetes Month               $5,000.00
 Pediatrico de           Celebration
 Diabetes
 
Garden State Equality   Teach and Affirm Students in           $2,500.00
 Education Fund Inc.     New Jersey
 
Global Healthy Living   Managed Care Organization             $24,000.00
 Foundation              Education (Overview)
 
Gordon Research         Gordon Research Atherosclerosis       $20,000.00
 Conference              Meeting
 
Governors Books From    Tennessee's Imagination Library        $2,500.00
 Birth Foundation        Program
 
Greater New England     Economic Development                   $4,000.00
 Minority Supplier
 Development Council
 
Health Action Council   Annual Conference                      $4,200.00
 
Healthcare              Woman of the Year                     $18,150.00
 Businesswomen's
 Association
 
HEART OF FLORIDA        SP 2014 United Way Campaign            $2,269.50
 UNITED WAY              Payout
 
Heart To Heart          US Crisis Readiness & Response        $10,000.00
 International Inc.
 
Idaho Immunization      Immunization Summit                    $2,000.00
 Coalition
 
Illinois Diabetes       Illinois Diabetes Caucus               $3,500.00
 Caucus Foundation       Foundation
 
Illinois                Business Day & Annual Lunch            $1,000.00
 Manufacturers'          Sponsorships
 Association
 
International Chinese   2015 International Chinese             $2,000.00
 Statistical             Statistical Association (ICSA)/
 Association             Graybi
 
International Eczema    International Eczema Council         $100,000.00
 Council
 
International Isotope   Sponsorship of 12th                    $3,250.00
 Society, Inc.           International Symposium on the
                         Synthesis
 
International Myeloma   9th Annual Comedy Celebration          $5,000.00
 Foundation              benefiting the Peter Boyle
                         Research Fund
 
International Myeloma   6th Annual International              $35,000.00
 Foundation              Myeloma Working Group Summit
 
International Myeloma   Patient Programs 2015                $100,000.00
 Foundation
 
International Society   RSG DREAM Conference                  $10,000.00
 for Computational
 Biology
 
International Society   25th ISHC Congress                     $1,000.00
 of Heterocyclic
 Chemistry
 
International Society   ACoP6                                  $5,000.00
 of Pharmacometrics
 
JDRF                    Imagine Gala                         $100,000.00
 
JDRF                    JDRF One Walk Philadelphia and         $2,500.00
                         Bucks County
 
JDRF                    JDRF One Walk                          $7,500.00
 
JDRF                    JDRF Central AR One Walk               $2,500.00
 
JDRF--Eastern PA        JDRF One Walk Moosic, Poconos,         $2,500.00
 Chapter                 Lehigh Valley and Berks County
 
JDRF Greater Dallas     JDRF One Walk, Dallas                  $2,500.00
 
JDRF International      JDRF One Walk Boston 2015             $10,000.00
 
JDRF International      JDRF OneWalk                           $5,000.00
 
JDRF International      JDRF Research Updates                  $2,000.00
 
Jefferson University    Quality and Safety Leadership        $100,000.00
 (School of Population   Series
 Health)
 
Jefferson University    Supporting Patient Access to          $79,700.00
 (School of Population   Diabetes Care: Follow-on to
 Health)                 Janua
 
Jersey Battered Womens  Vocational Development Program         $5,000.00
 Service
 
Joslin Diabetes         A Taste of Ginger                     $25,000.00
 Center, Inc.
 
Joslin Diabetes         National Diabetes Month/High          $50,000.00
 Center, Inc.            Hopes Gala
 
Juvenile Diabetes       Rock the Cure                          $1,000.00
 Research Foundation
 
Kean University         2015 Group Summer Scholars            $15,000.00
 Foundation Inc.         Research Program
 
Keystone Symposia on    Cancer Immunotherapy: Immunity        $25,000.00
 Molecular and           and Immunosuppression Meds
 Cellular Biology
 
Kidney Health Alliance  Share Your Spare 5k for Get              $750.00
 of KY                   Healthy Get Transplanted
 
Kids Corporation li     Kids Corp General Operating           $10,000.00
 
Lagrant Foundation      Internship Program                    $25,000.00
 
Large Urological Group  LUGPA Annual Meeting Gold Level       $85,000.00
 Practice Association    Membership
 LUGPA
 
Leukemia & Lymphoma      Man & Woman of the Year               $3,500.00
 Society
 
Living Well Cancer      General Operating Support              $2,500.00
 Resource Center
 
MA Conference for       MA Conference for Women               $20,000.00
 Women Inc.
 
Map International       United States Disaster Relief         $10,000.00
 
March of Dimes          Supporting NICU Babies and            $86,000.00
 Foundation              Families
 
Maryland Health Care    Specialty Rx Forum                     $7,500.00
 Coalition DBA
 MidAtlantic Business
 Group on Health Care
 
Massachusetts           Annual Conference. Payment             $2,000.00
 Association of Health   Reform--Three Years Later
 Plans
 
MedStar Washington      MedStar Washington Medical             $3,000.00
 Hospital Center         Center--Current Issues in the
                         Care
 
Mended Hearts           Patient Advocacy Network             $100,000.00
 
Mended Hearts           2015 Mended Hearts National           $50,000.00
                         Education and Training
                         Conference
 
Michigan Biosciences    MichBio Conference Description         $1,500.00
 Industry Association
 
Mid Atlantic Lifespan,  Senior Care Providers                  $4,000.00
 Inc.                    Roundtables With Local
                         Hospitals
 
Midland Adult Services  Midland Meals on Wheels               $10,000.00
 Inc.                    Employment Training Program
 
Migrant Clinicians      Health Champions: Reducing               $500.00
 Network                 Disease to Improve Health
 
Milken Institute        The Research Acceleration and         $10,000.00
                         Innovation Network (TRAIN)
 
Milken Institute        2015 Milken Institute              $1,000,000.00
                         Conference Sponsorships &
                         Engagement
 
Minnesota Society of    MSHP Corporate Sponsorship             $6,000.00
 Health-System
 Pharmacists
 
MIT                     13th US-Japan Symposium on Drug        $7,000.00
                         Delivery Systems
 
MIT                     14th Annual Koch Institute             $5,000.00
                         Summer Symposium ``CANCER
                         COMMITTEE''
 
MIT $100K Competition   MIT $100K Competition                 $25,000.00
 
Multiple Myeloma        Advances in Minimal Residual          $25,000.00
 Research Foundation     Disease Testing in Myeloma
 
Multiple Myeloma        Advances in Minimal Residual          $25,000.00
 Research Foundation     Disease Testing in Myeloma
 
NATIONAL ACADEMY OF     Forum on Drug Discovery,              $85,000.00
 SCIENCES                Development and Translation
 
National Alliance of    11th Annual Meeting                    $5,000.00
 State Prostate Cancer
 Coalitions
 
National Arbor Day      Chippewa National Forest tree          $4,138.00
 Foundation              planting
 
National Association    Childhood Obesity                     $10,000.00
 for the Advancement
 of Colored People
 
National Committee for  NCQA's 25th Anniversary               $10,000.00
 Quality Assurance
 (``NCQA'')
 
National Consumers      Health Policies for Better             $5,000.00
 League                  Outcomes and Balanced Budgets
 
National Eczema         The Decade of Eczema: Roadmap        $200,000.00
 Association             to Advocacy
 
National Forum for      13th Annual Meeting of the            $25,000.00
 Heart Disease and       National Forum for Heart
 Stroke Prevention       Disease and Stoke Prevention
 Inc.
 
National Foundation     TB Trials Consortium                 $671,292.00
 For The Ctrs For
 Disease Contr &
 Prevention Inc.
 
National Health         Voluntary Health Leadership           $20,000.00
 Council                 Conference
 
National Health         Policy Development Fund               $70,000.00
 Council
 
National Kidney         Patient Empowerment Workshop           $2,000.00
 Foundation
 
National Kidney         Kansas City Kidney Walk                $1,000.00
 Foundation
 
National Kidney         Wichita Kidney Walk                      $250.00
 Foundation
 
National Kidney         2015 Boston Kidney Walk               $15,000.00
 Foundation
 
National Kidney         Champion of Hope Tribute Dinner        $1,000.00
 Foundation of
 Michigan
 
National Kidney         Gift of Life Gala                      $1,500.00
 Foundation of West
 Tennessee
 
National Kidney         NKF of West Tennessee Wolf Mash          $250.00
 Foundation of West      Dash 5K
 Tennessee
 
National Kidney         2015 New York City Kidney Walk        $25,000.00
 Foundation, Inc.
 
National Kidney         NKF Cares 2015                        $25,000.00
 Foundation, Inc.
 
National Kidney         NKF Peers 2015                        $25,000.00
 Foundation, Inc.
 
National Kidney         Eight Annual Mid-Atlantic First        $5,000.00
 Foundation, Inc.        Year Renal Fellowship
                         Symposium
 
National Kidney         7th Annual Central New Jersey          $1,000.00
 Foundation, Inc.        Kidney Walk
 
National Kidney         Philadelphia Kidney Walk                 $500.00
 Foundation, Inc.
 
National Kidney         Chester County Kidney Walk               $500.00
 Foundation, Inc.
 
National Kidney         Wilmington Kidney Walk                   $500.00
 Foundation, Inc.
 
National Kidney         Pittsburgh Kidney Walk                   $500.00
 Foundation, Inc.
 
National Kidney         Northeast Ohio Kidney Walk             $1,000.00
 Foundation, Inc.
 Serving Ohio
 
National Kidney         2015 Patient Symposium                 $1,000.00
 Foundation, Inc.
 Serving Ohio
 
National Patient        NPAF Policy Consortium                $20,000.00
 Advocate Foundation
 
National Press          Training Journalists on               $40,000.00
 Foundation              Advances in Biologics and
                         Biosimilars
 
National TB             2015 National TB Conference:             $500.00
 Controllers             Sponsorship Request
 Association
 
National Transitions    National Transition of Care          $250,000.00
 of Care Coalition       Coalition
 
NBCH                    Hypoglycemia Action Brief             $17,500.00
 
NBCH                    Annual Conference                      $3,500.00
 
NBCH                    ASCVD Action Brief                    $17,500.00
 
NCOMS                   NC Oncology Management Society         $5,000.00
 
NEHI                    New Policy: Better Use of             $25,000.00
                         Medicines in Diabetes
 
Neuropathy Action       9th Annual ``Neuropathy Action         $2,500.00
 Foundation              Awareness Day''
 
 New Jersey Hall of     Mobile Museum                          $2,500.00
 Fame
 
New Jersey Public       NJPHA Sponsorship                      $5,000.00
 Health Association
 
New York Stem Cell      NYSCF 10th Annual Translational        $2,000.00
 Foundation, Inc.        Stem Cell Research Conference
 
NJ SEEDS                College Scholars Program              $10,000.00
 
North Coast Health      Celebration of Caring                  $2,500.00
 
Northeast Business      eValue8 - Health Plan                  $9,000.00
 Group on Health         Performance Review
 
Northeast Business      Specialty Pharmacy Conference          $5,000.00
 Group on Health
 
Northeastern Section    German Exchange Program                $2,000.00
 of the American
 Chemical Society
 
NSHMBA Foundation       NSHMBA New Jersey Annual               $5,000.00
                         Partnership
 
Oklahoma Center for     The transformation of                  $3,500.00
 Healthcare              Healthcare
 Improvement
 
Opportunity Through     Arizona Pavilion at BIO 2015           $1,000.00
 Entrepreneurship
 Foundation
 
Organization for        OFII Annual Dinner                    $15,000.00
 International
 Investment
 
Partnership For         2016 Membership Dues                  $19,000.00
 Quality Medical
 Donations
 
Patient Advocate        Prostate and CRC Co-Pay Relief       $550,000.00
 Foundation              Fund
 
PATIENT EMPOWERMENT     The Latest News on Advanced           $20,000.00
 NETWORK                 Prostate Cancer Research and
                         Treatment
 
PCMA                    2015 sPCMA Business Forum             $60,000.00
                         Sponsorship
 
PCMA                    2015 Annual Meeting                   $75,000.00
                         Presidential Sponsorship
 
Pediatric Cancer        NHL 2015 Pediatric Sponsorship        $10,000.00
 Research Foundation
 
Pennsylvania            CBO Dinner                             $5,000.00
 Biotechnology
 Association
 
Perimeter Bicycling     2015 El Tour de Tucson                $15,000.00
 Association of
 America, Inc.
 
Pharmaceutical          PhRMA Foundation Grants and          $100,000.00
 Research and            Fellowships
 Manufacturers of
 America Foundation
 
Premier Cares           Premier Cares Foundation               $1,500.00
 Foundation              Prostate Cancer Walk
 
Preventive              Cholesterol Patient Education        $100,000.00
 Cardiovascular Nurses
 Association
 
PRIDE                   PRIDE Conference                       $6,000.00
 
Project Hope The        Responding to the Nepal               $10,000.00
 People To People        Earthquake
 Health Foundation
 Inc.
 
Prostate Cancer         22nd Annual Scientific Retreat       $300,000.00
 Foundation
 
Raritan Valley          Galileo Scholarships: Providing       $17,500.00
 Community College       Access to STEM Education
 Foundation
 
Raritan Valley          Preparing for the Next                $10,000.00
 Community College       Generation Science Standards
 Foundation
 
Regents of the          V-BID Summit 2015: A Decade of        $40,000.00
 University of           Transforming the Health Care
 Michigan
 
Renal Support Network   KidneyTalk Podcast                     $1,000.00
 
Renal Support Network   Live & Give Newsletter                 $1,500.00
 
Renal Support Network   CKD Patient Education Meetin           $1,500.00
 
Renal Support Network   13th Annual Patient Essay              $1,000.00
                         Contest
 
Resource Center of      Transitional Housing Program           $5,000.00
 Somerset Inc.
 
Rutgers University      Vets 4 Warriors                       $10,000.00
 Foundation
 
RVCC Foundation         STEM Education: Equity Issues         $10,000.00
                         and Workforce Pipeline
 
RVCC Foundation         College Campus Experience Day          $3,000.00
                         for STEM High School Students
 
Sage Bionetworks         2015 Paris Assembly                  $15,000.00
 
Sanofi US Matching      Sanofi US Matching Gifts--Q2         $277,628.31
 Gifts--2015             2015
 
Sanofi US Matching      Sanofi US Matching Gifts--Q1         $427,531.29
 Gifts--2015             2015
 
SARSEF-SOUTHERN         The Future of Biomedical               $5,000.00
 ARIZONA RESEARCH        Research
 SCIENCE AND
 ENGINEERING
 
Scripps Translational   The Future of Genomic Medicine        $10,000.00
 Science Institute       VIII
 
Society of Toxicologic  2015 ACVP/ASVCP/STP Combined           $2,500.00
 Pathology               Annual Meeting
 
Society of Toxicology   Society of Toxicology Annual          $10,000.00
                         Meeting
 
Somerset County         SCBP 2015 program of work             $20,000.00
 Business Partnership
 
Somerset Medical        Fun 'N Fit                            $25,000.00
 Center Foundation
 Inc.
 
Somerset Medical        EMS Program                            $5,000.00
 Center Foundation
 Inc.
 
Somerset Medical        El Poder Sobre La Diabetes            $10,000.00
 Center Foundation
 Inc.
 
South Dakota Diabetes   Virtual Nurse Model: School            $5,100.00
 Coalition               Project
 
 St. Louis Children's   Food Allergy Management and           $75,000.00
 Hospital Foundation     Education
 
Stop Hunger Now Inc.    Stop Hunger Now Program               $10,000.00
                         Expansion to New York City
                         Metro
 
Stowe Weekend of Hope   Stowe Weekend of Hope                  $5,000.00
 
T. Leroy Jefferson      2015 Community Health Fair             $2,500.00
 Medical Society
 
Taking Control of Your  The 9th Annual Diabetes Forum         $10,000.00
 Diabetes
 
Tennessee Kidney        2015 Gift of Life Walk/5K              $2,000.00
 Foundation
 
Tennessee Kidney        Spring Soiree 2015                     $2,500.00
 Foundation
 
Teratology Society      Teratology Society 55th Annual         $1,500.00
                         Meeting
 
The American            Major Symposia--Roots and             $10,000.00
 Association of          Mechanisms of Human Autoimmun
 Immunologists, Inc.
 
The American College    ACVP/ASVCP/STP Combined Annual         $6,000.00
 of Veterinary           Meeting
 Pathologists
 
The American Fallen     Portrait Sponsorship                  $25,000.00
 Soldiers Project Inc.
 
The American Kidney     A Pairing for Prevention 2015          $5,000.00
 Fund, Inc.
 
The American Kidney     The Hope Affair 2015                  $50,000.00
 Fund, Inc.
 
The American Kidney     9th Annual New York Spring             $1,500.00
 Fund, Inc.              Event
 
The Bus Stops Here      Hall Of Fame Induction for            $35,000.00
 Foundation              Jerome Bettis
 
The Center For Great    Adult Women's Program                 $10,000.00
 Expectations Inc.
 
The Childrens Health    Medical Home Initiative              $665,000.00
 Fund
 
The Cleveland Clinic    A Celebration of Survivorship          $5,000.00
 Foundation-BMT          An Educational Symposium for
 Cleveland Clinic        BM
 Sponsorship
 
The Council of State    Bowhay Institute for                   $5,000.00
 Government, Ltd.        Legislative Leadership
                         Development
 
The Diabetes Coalition  Giving Diabetes the Blues              $2,500.00
 of Mississippi/
 Mississippi Rural
 Health Association
 
The FH Foundation       CASCADE FH Registry                  $500,000.00
 
The Flood Sisters       7th Annual Love.Give.Life.             $2,000.00
 Kidney Foundation of    Fashion Show/Gala
 America
 
The Friends of Matheny  Matheny Center of Medicine and         $5,000.00
                         Dentistry
 
The Life Raft Group     Research Team Meeting                  $5,000.00
 
The Salvation Army      Healthy Food Pantry Program            $5,000.00
 
The University of       First Annual Immuno-Oncology in       $25,000.00
 Texas Foundation,       Myeloma 2015 Workshop
 Inc.
 
Trustees of Boston      Boston University's 15th Annual        $1,500.00
 University              CMD Symposium on Molecular
                         Discovery
 
Trustees of the         Research Training in                  $20,000.00
 University of           Pharmacoepidemiology
 Pennsylvania
 
Tufts Medical Center    CEVR Database Subscription            $35,000.00
 
TULANE CANCER CENTER    NOLA Bluedoo Party/Walk/Run            $1,000.00
 
Tuskegee Human And      Donation for Public Education          $5,000.00
 Civil Rights
 Multicultural Center
 
UCSF Cancer Center (c/  2015 HDFCCC Symposium:                 $5,000.00
 o UCSF Foundation)      Breakthroughs in Cancer
                         Immunotherapy
 
United Network for      Transplant Living Program             $25,000.00
 Organ Sharing
 
United States Soccer    Soccer for Success--Paterson,         $10,000.00
 Federation Foundation   NJ
 Inc.
 
United Way of Greater   Merial--Duluth 2014 United Way        $23,984.25
 Atlanta                 Campaign
 
United Way of Hall      2014 United Way Campaign Match--       $2,841.50
 County Inc.             Merial Select
 
United Way of           SP 2014 United Way Campaign            $7,221.00
 Lackawanna and Wayne    Payout
 Counties
 
United Way of           Sanofi Pasteur 2014 United Way           $521.00
 Massachusetts Bay       Campaign Payout
 Inc.
 
United Way of Monroe    SP 2014 United Way Campaign           $56,881.53
 County                  Match
 
United Way of           2014 United Way Campaign--             $5,000.00
 Northeast Georgia       Merial Athens
 
United Way of Northern  Caregivers Coalition                 $100,000.00
 New Jersey
 
Unitio Inc.             T1D Education Event Series            $45,000.00
 
Univeristy of Arizona    Alternative Muscle Club               $2,700.00
 Foundation for the      meeting
 benefit of Univeristy
 of Arizona
 
University of Arizona   Support for the Undergraduate          $3,000.00
 Foundation              Biology Research Program
                         Conference
 
University of Arizona   Applied Biosciences GIDP Merit         $5,000.00
 Foundation              Scholarship
 
University of Arizona   Keep Engaging Youth in Science         $6,400.00
 Foundation              (KEYS) High School Summer
                         Internships
 
University of           UCSF Diabetes Center 15th              $5,000.00
 California, San         Anniversary Symposium
 Francsico Foundation
 
University of Florida   New Developments in Clinical           $1,000.00
 Foundation, Inc.        Pharmacy and Clinical
                         Pharmacology
 
UNIVERSITY OF MARYLAND  M-Cersi Conference on Patient         $10,000.00
 BALTIMORE FOUNDATION    Focused Drug Development
 INC.
 
University of North     Pharmacoepidemiology Program          $20,000.00
 Carolina at Chapel      Donation
 Hill
 
University of Southern  USC/UCLA/UCSF Tri-Institutional        $3,000.00
 California              Retreat
 
University of Southern  National Unity 2015 Conference:        $5,000.00
 Mississippi             Community Health Workers
 Foundation
 
US China Health Summit  5th US-China Health Summit at         $70,000.00
 Inc.                    Harvard University
 
Us TOO International    Us TOO 25th Anniversary               $10,000.00
                         Educational Symposium & Gala
                         Celebration
 
Vision y Compromiso     13th Annual Promotoras and            $10,000.00
                         Community Health Workers
                         Conference
 
Washington Legal        2015 General Operating Support        $25,000.00
 Foundation
 
Washington Policy       WPC's 2015 Annual Dinner               $3,500.00
 Center
 
Wellness Community of   School-Based Support Groups           $15,000.00
 Central New Jersey
 
Winter Urologic Forum   Winter Urologic Forum (WUF)           $15,000.00
 (WUF)                   Symposia Timeslot
 
WomenHeart: The         WomenHeart Science & Leadership       $50,000.00
 National Coalition      Symposium
 for Women with Heart
 Disease
 
WomenHeart: The         National Science & Policy             $25,000.00
 National Coalition      Summit on Women's Heart Health
 for Women with Heart
 Disease
 
Women's Venture Fund    Highest Leaf Awards                   $15,000.00
 
YMCA of Greater Boston  YMCA's Diabetes Prevention             $5,000.00
                         Program
 
ZERO--The End of        ZERO Prostate Cancer Run/Walk          $1,500.00
 Prostate Cancer         Delaware
------------------------------------------------------------------------


                    Payments made by Sanofi US (2016)
------------------------------------------------------------------------
      Legal Name         Payment Amount           Project Title
------------------------------------------------------------------------
AMERICAN DIABETES              $48,070   American Diabetes Association
 ASSOCIATION EXPOS                        EXPO
------------------------------------------------------------------------
American Society of            $35,000   AMERICAN ASSOCIATION FOR CANCER
 Transplant Surgeons                      RESEARCH--Networking Hub
------------------------------------------------------------------------
American Society of            $35,000   American Society of Transplant
 Transplant Surgeons                      Surgeons--Bronze Level Support
------------------------------------------------------------------------
Taking Control of Your        $200,000   Taking Control of Your
 Diabetes                                 Diabetes--Gold Sponsorship
------------------------------------------------------------------------
Children with Diabetes         $35,000   2016 Children with Diabetes
                                          (CWD) Sponsorship
------------------------------------------------------------------------
MedStar Washington              $3,000   MedStar Washington Hospital
 Medical Center                           Center--Current Issues in the
                                          Care of Dialysis and
                                          Transplant Patient
------------------------------------------------------------------------
Joslin Diabetes                $25,000   A Taste of Ginger
 Center, Inc.
------------------------------------------------------------------------
Massachusetts General           $5,000   Collaborative Novel-Novel
 Hospital                                 Combination Therapies Workshop
------------------------------------------------------------------------
Greater New England             $7,000   Economic Development
 Minority Supplier
------------------------------------------------------------------------
Healthy Capital                 $2,500   Diabetes Community Resource
 District Initative                       Guide
------------------------------------------------------------------------
American Diabetes               $2,500   Get Moving Challenge
 Association
------------------------------------------------------------------------
American Diabetes               $2,500   Tour de Cure
 Association
------------------------------------------------------------------------
American Diabetes               $2,500   2016 Step Out: Walk to Stop
 Association                              Diabetes
------------------------------------------------------------------------
AMERICAN DIABETES               $2,500   Father of the Year Awards Gala
 ASSOCIATION INC.
------------------------------------------------------------------------
Buffalo American                $2,500   2016 Buffalo Niagara Tour de
 Diabetes Association                     Cure
------------------------------------------------------------------------
CNY American Diabetes           $2,500   2016 Tour de Cure
 Association
------------------------------------------------------------------------
Albany American                 $2,500   Saratoga Springs Tour de Cure
 Diabetes Association
------------------------------------------------------------------------
American Diabetes               $2,500   Tour de Cure Michigan
 Association
------------------------------------------------------------------------
American Diabetes               $2,000   2016 Finger Lakes Tour de Cure
 Association Inc.
------------------------------------------------------------------------
American Diabetes              $10,000   2016 High Risk Community
 Association                              Initiatives for Southwest
                                          Florida
------------------------------------------------------------------------
American Diabetes               $2,500   Charlotte Step Out: Walk to
 Association                              Stop Diabetes
------------------------------------------------------------------------
American Diabetes               $2,500   Tour de Cure Hawaii
 Association
------------------------------------------------------------------------
American Diabetes               $2,500   Step Out: Walk to Stop Diabetes
 Association                              Upstate, SC
------------------------------------------------------------------------
American Diabetes               $2,500   American Diabetes Association's
 Association                              Boston Step Out Walk to STOP
                                          Diabetes
------------------------------------------------------------------------
American Diabetes               $2,500   American Diabetes Association's
 Association                              Connecticut Step Out Walk to
                                          STOP Diabetes
------------------------------------------------------------------------
American Diabetes               $2,500   American Diabetes Association's
 Association                              Central Massachusetts Step Out
                                          Walk to STOP Diabetes
------------------------------------------------------------------------
American Diabetes               $2,500   2016 New Orleans Father of the
 Association                              Year
------------------------------------------------------------------------
American Diabetes               $2,500   2016 Indiana Tour de Cure
 Association, Indiana
------------------------------------------------------------------------
AMERICAN DIABETES              $75,000   Diabetes Hospitality Days: Stop
 ASSOCIATION INC                          Diabetes in New Orleans
------------------------------------------------------------------------
National Kidney                $25,000   NKF Patient Programs 2016
 Foundation, Inc.
------------------------------------------------------------------------
Asthma and Allergy            $100,000   AAFA Patient Education and
 Foundation of America                    Outreach
------------------------------------------------------------------------
Asthma and Allergy             $10,000   KFA Strides for Safe Kids Mall
 Foundation of America                    Walk and Expo
------------------------------------------------------------------------
Asthma and Allergy             $15,000   KFA Patient Education and
 Foundation of America                    Outreach
------------------------------------------------------------------------
Northeast Business             $20,000   eValue8--Health Plan
 Group on Health                          Performance Review
------------------------------------------------------------------------
Food Allergy Research         $100,000   FOOD ALLERGY 101 Online
 Education                                Training Component and School
                                          Action Campaign Grassroots
                                          Advocacy
------------------------------------------------------------------------
American Heart                  $2,000   Peoria Heart and Stroke Ball
 Association |                            and Peoria and Bloomington
 American Stroke                          Heart Walk
 Association
------------------------------------------------------------------------
American Heart                 $15,000   2016 Heart Innovation Forum
 Association
------------------------------------------------------------------------
American Heart                  $2,000   Springfield Heart Ball
 Association |
 American Stroke
 Association
------------------------------------------------------------------------
ATS Foundation Inc             $25,000   Eighth Annual ATS Foundation
                                          Research Program Benefit
------------------------------------------------------------------------
BHCAG FOUNDATION                $2,500   Employer Leadership Summit
------------------------------------------------------------------------
National Alliance of            $5,000   11th Annual Meeting
 State Prostate Cancer
 Coalitions
------------------------------------------------------------------------
New York Stem Cell              $2,000   The NYSCF Conference
 Foundation, Inc.
------------------------------------------------------------------------
Opportunity Through             $1,000   Arizona Pavilion at BIO 2016
 Entrepreneurship
 Foundation
------------------------------------------------------------------------
Somerset Health Care            $1,000   Healthier Somerset
 Foundation
------------------------------------------------------------------------
Diabetes Foundation            $10,000   25th Anniversary Awards Dinner
 Inc.                                     & Talent Competition
------------------------------------------------------------------------
JDRF                            $2,500   One Walk Philadelphia
------------------------------------------------------------------------
JDRF                            $2,500   JDRF One Promise Gala
                                          Allentown--Passport to a Cure
------------------------------------------------------------------------
JDRF                            $2,500   Rockin' Docs for Diabetes Cure
------------------------------------------------------------------------
JDRF                            $2,500   2016 JDRF Poconos One Walk
------------------------------------------------------------------------
JDRF                           $12,000   JDRF One Promise Gala
                                          Philadelphia
------------------------------------------------------------------------
JDRF                            $2,500   2016 JDRF Moosic One Walk
------------------------------------------------------------------------
JDRF                            $2,500   2016 JDRF Reading One Walk
------------------------------------------------------------------------
JDRF                            $2,500   One Walk Newtown
------------------------------------------------------------------------
JDRF                            $2,500   2016 JDRF Lehigh Valley One
                                          Walk
------------------------------------------------------------------------
JDRF                            $2,500   ACE For A Cure
------------------------------------------------------------------------
JDRF Central PA                 $2,500   JDRF One Walk--Lancaster
 Chapter
------------------------------------------------------------------------
JDRF New York City             $15,000   44th Annual Promise Ball
 Chapter
------------------------------------------------------------------------
JDRF International              $2,500   34th Annual Boston Gala
------------------------------------------------------------------------
JDRF INTERNATIONAL             $50,000   2016 TypeOneNation Summits
------------------------------------------------------------------------
JDRF INTERNATIONAL             $50,000   2016 JDRF Government Day
------------------------------------------------------------------------
JDRF Greater Dallas             $2,500   JDRF One Walk, Dallas
------------------------------------------------------------------------
Juvenile Diabetes               $2,500   Rock the Cure
 Research Foundation
------------------------------------------------------------------------
JDRF                           $10,000   JDRF Imagine Gala
------------------------------------------------------------------------
National Comprehensive         $10,000   Emerging Issues in Oncology--An
 Cancer Network                           NCCN Roundtable Discussion
------------------------------------------------------------------------
American Society for            $2,500   ASN Annual Meeting
 Neurochemistry
------------------------------------------------------------------------
American Orthopaedic           $50,000   Early Osteoarthritis/Prevention
 Society for Sports                       of Disease Progression
 Medicine
------------------------------------------------------------------------
Diabetes Foundation of          $2,000   LIVE-A-BETES: Learning To Live
 Mississippi                              Well With Diabetes
------------------------------------------------------------------------
Renal Physicians               $10,000   RPA Kidney Quality Improvement
 Association                              Registry
------------------------------------------------------------------------
New York & New Jersey           $8,000   Annual Sponsorship
 Minority Supplier
 Development Council
------------------------------------------------------------------------
Gordon Research                 $3,000   2016 Gordon Research Conference
 Conference                               (GRC) entitled Autophagy in
                                          Stress, Development, and
                                          Disease: From the basics to
                                          therapeutic targets
------------------------------------------------------------------------
Gordon Research                 $2,000   Drug Carriers in Medicine and
 Conference                               Biology
------------------------------------------------------------------------
Gordon Research                $10,000   Gordon Research Conference
 Conference                               Antibody Biology & Engineering
                                          March 2016
------------------------------------------------------------------------
PATIENT EMPOWERMENT            $20,000   2016 Town Meeting for Advanced
 NETWORK                                  Prostate Cancer Patients
------------------------------------------------------------------------
PATIENT EMPOWERMENT            $25,000   Online Advanced Prostate News
 NETWORK                                  Coverage for Patients
------------------------------------------------------------------------
Bioscience Association          $1,500   WV Bioscience Summit 2016
 of WV
------------------------------------------------------------------------
Arthritis Foundation            $2,000   Sponsorship for Arthritis
                                          Foundation Crystal Ball
------------------------------------------------------------------------
National Transitions          $125,000   NTOCC
 of Care Coalition
------------------------------------------------------------------------
American Medical               $50,000   AMSSM Foundation Research Grant
 Society for Sports                       Awards
 Medicine Foundation,
 Inc.
------------------------------------------------------------------------
Biocom                         $10,000   Global Life Science Partnering
                                          Conference
------------------------------------------------------------------------
Biocom                         $10,000   Global Life Science Partnering
                                          Conference
------------------------------------------------------------------------
Taking Control of Your        $200,000   Taking Control Of Your Diabetes
 Diabetes                                 Conferences and Health Fairs
------------------------------------------------------------------------
Prescription Drug               $1,000   Legislative Reception and
 Assistance Foundation                    Celebration of Access
------------------------------------------------------------------------
The Cleveland Clinic           $95,275   Advances in Organ
 Foundation                               Transplantation--Annual
                                          Fellows Conference
------------------------------------------------------------------------
Employers Health                $6,500   Employer Health 2016 Annual
 Coalition, Inc.                          Symposium
------------------------------------------------------------------------
Respiratory Health                $750   Lung Health Education
 Association
------------------------------------------------------------------------
Us TOO International           $15,000   Prostate Cancer News You Can
                                          Use
------------------------------------------------------------------------
Us TOO International            $5,000   Prostate Cancer Educational
                                          Webinar
------------------------------------------------------------------------
Us TOO International            $5,000   Us TOO Prostate Cancer Business
                                          Leadership Council
------------------------------------------------------------------------
Blood and Marrow               $25,000   Celebrating a Second Chance at
 Transplant                               Life 2016 Survivorship
 Information Network                      Symposium
------------------------------------------------------------------------
Blood and Marrow                $7,500   2016 BMT InfoNet Transplant
 Transplant                               Webinar Series
 Information Network
------------------------------------------------------------------------
PCMA                           $80,000   2016 sPCMA Business Forum
------------------------------------------------------------------------
PCMA                           $95,000   2016 Annual Meeting
                                          Presidential Sponsorship
------------------------------------------------------------------------
Regents of the                 $40,000   V-BID Summit 2016
 University of
 Michigan
------------------------------------------------------------------------
Minnesota Society of            $6,000   MSHP 2016 Corporate Business
 Health-System                            Partnership Program
 Pharmacists
------------------------------------------------------------------------
Be The Match                   $25,000   National Sponsorship for Be The
 Foundation                               Match Walk+Run
------------------------------------------------------------------------
Mid-America Coalition           $5,000   4th Annual Workforce &
 on Health Care                           Community Well-Being Forum
------------------------------------------------------------------------
Global Virus Network,          $10,000   8th International Global Virus
 Inc.                                     Network Meeting
------------------------------------------------------------------------
CrowdCare Foundation,          $10,000   Muscles for Myeloma
 Inc.
------------------------------------------------------------------------
PRIDE                           $6,000   PRIDE Conference
------------------------------------------------------------------------
The diaTribe                  $100,000   d16 Executive Forum
 Foundation
------------------------------------------------------------------------
US China Health Summit         $70,000   5th US-China Health Summit at
 Inc.                                     Harvard University
------------------------------------------------------------------------
Greater Philadelphia            $5,000   GPBCH 2016 Annual Conference
 Business Coalition on
 Health
------------------------------------------------------------------------
Food Allergy &                $100,000   FAACT Education Programs
 Anaphylaxis
 Connection Team
------------------------------------------------------------------------
Deep South Cancer               $5,000   2016 Cycliad Charity Bicycle
 Foundation                               Ride
------------------------------------------------------------------------
California Life                 $2,500   CLSA Life Sciences Academy
 Sciences Association
------------------------------------------------------------------------
Globalization of                $3,500   GPEN2016
 Pharmaceutics
 Education Network,
 Inc.
------------------------------------------------------------------------
American Association           $20,000   Public Policy Forum 2016
 of Diabetes Educators
------------------------------------------------------------------------
Federation of American          $5,000   FASEB conference on Muscle
 Societies for                            Satellite Cells and
 Experimental Biology                     Regeneration
 (FASEB)
------------------------------------------------------------------------
Teratology Society              $1,500   Teratology Society 56th Annual
                                          Meeting
------------------------------------------------------------------------
Biotechnology                 $145,000   BIO International Convention
 Innovation
 Organization
------------------------------------------------------------------------
Biotechnology                  $40,000   BIO Europe Spring and BIO
 Innovation                               Europe International
 Organization                             Partnering Conference
------------------------------------------------------------------------
Maryland Black Caucus           $2,000   Maryland Black Caucus
 Foundation, Inc.                         Foundation, Inc.
------------------------------------------------------------------------
American Cancer                $25,083   2016 ACS CAN Fundraising Events
 Society Cancer Action                    and ACS CAN advocacy
 Network                                  activities
------------------------------------------------------------------------
Mid Atlantic Lifespan,          $4,000   Senior Care Providers
 Inc.                                     Roundtables With Local
                                          Hospitals
------------------------------------------------------------------------
ACS Organic Chemistry           $1,500   ACS-DOC Graduate Research
 Division                                 Symposium
------------------------------------------------------------------------
Society of Toxicology          $10,000   Society of Toxicology Annual
                                          Meeting
------------------------------------------------------------------------
NATIONAL ACADEMY OF            $50,000   Forum on Neuroscience and
 SCIENCES                                 Nervous System Disorders
------------------------------------------------------------------------
NATIONAL ACADEMY OF            $85,000   Forum on Drug Discovery,
 SCIENCES                                 Development and Translation
------------------------------------------------------------------------
Allergy & Asthma              $100,000   AAP Asthma, Allergy &
 Network Mothers of                       Anaphylaxis Champion Program
 Asthmatics
------------------------------------------------------------------------
Virginia Bio                    $1,500   Legislative Reception
------------------------------------------------------------------------
AMGA Foundation Inc           $200,000   Together 2 Goal
------------------------------------------------------------------------
International Society          $70,000   World Kidney Day 2016
 of Nephrology
------------------------------------------------------------------------
Florida Health Care             $7,500   ``The Health Care Revolution:
 Coalition                                Building the Health Rosetta''
------------------------------------------------------------------------
Florida Caucus of               $2,000    Scholarship
 Black State
 Legislators
------------------------------------------------------------------------
Fundacion Centro               $15,000   Diabetes Summer Camp 2016
 Pediatrico de
 Diabetes
------------------------------------------------------------------------
American Drug                  $15,000   American Drug Utilization
 Utilization Review                       Review Symposium
 Society
------------------------------------------------------------------------
The University of              $25,000   Second Annual Immuno-Oncology
 Texas Foundation,                        and Myeloma Workshop
 Inc.
------------------------------------------------------------------------
El Paso Diabetes                $2,500   2016 Diabetes Walk/Run
 Association, Inc.
------------------------------------------------------------------------
National TB                     $2,500   Using the Stories and Voices of
 Controllers                              TB Survivors for Patient
 Association                              Education, Building a
                                          Supportive Community, and
                                          Advocacy
------------------------------------------------------------------------
French American                 $1,000    FACS XVI
 Chemical Society
------------------------------------------------------------------------
Texas Tech Foundation,        $286,000   Community Health Worker (CHW)
 Inc.                                     Core Consensus Project 2016:
                                          Increasing Stakeholder
                                          Engagement and Endorsement,
                                          Defining CHW Roles and Skills
                                          in Clinical and Community
                                          Settings, and CHW Skill
                                          Assessment Approaches and
                                          Tools
------------------------------------------------------------------------
Houston Business                $6,000   The Employer's Specialty
 Coalition on Health                      Pharmaceutical Dilemma--
                                          Challenges & Opportunities
------------------------------------------------------------------------
UNM Comprehensive               $1,000   Hoops4Hope
 Cancer Center
------------------------------------------------------------------------
University of Utah             $50,000   Western Atrial Fibrillation
                                          Symposium
------------------------------------------------------------------------
WithinReach                     $5,000   Improving Health Access and
                                          Immunization Policy
------------------------------------------------------------------------
NASPA                           $5,000   NASPA Leadership Conference
                                          Awareness Walk
------------------------------------------------------------------------
National Eczema               $300,000   Roadmap to Advocacy
 Association
------------------------------------------------------------------------
American Society on             $5,000   2016 Aging in America
 Aging                                    Conference
------------------------------------------------------------------------
Milken Institute              $500,000   2016 Milken Institute
                                          Conference Engagement
------------------------------------------------------------------------
International Myeloma         $100,000   IMF Patient Programs 2016
 Foundation
------------------------------------------------------------------------
International Myeloma           $5,000   IMF 10th Annual Comedy
 Foundation                               Celebration benefitting the
                                          Peter Boyle Research
                                          Foundation
------------------------------------------------------------------------
International Myeloma          $35,000   7th Annual Internaltional
 Foundation                               Myeloma Working Group Summit
------------------------------------------------------------------------
California Center for           $2,500   Pre-diabetes Epidemic in
 Public Health                            California--What Now?
 Advocacy
------------------------------------------------------------------------
Out & Equal                    $25,000   2016 Out & Equal Workplace
                                          Summit
------------------------------------------------------------------------
GLBTQ Legal Advocates           $3,000   GLAD 2016 Summer Party
 & Defenders
------------------------------------------------------------------------
Gay Men's Health                $5,000   AIDS Walk New York
 Crisis, Inc
------------------------------------------------------------------------
The Children's Aid             $25,000   The Children's Aid Society 5th
 Society                                  Annual KTP Gala
------------------------------------------------------------------------
Jersey Battered                 $7,000   JBWS Grand Tastings XXII
 Women's Service, Inc.
------------------------------------------------------------------------
Community Hope, Inc.           $10,000   2016 Silver Corporate Partner
------------------------------------------------------------------------
RESOURCES USA INC               $7,500   French Talks
------------------------------------------------------------------------
Court Appointed                 $1,000   Night of a Thousand Stars Gala
 Special Advocates of
 Mercer County, Inc.
------------------------------------------------------------------------
Machestic Dragons               $5,000   10th Annual ``Paddle for Pink''
                                          Community Dragon Boat Festival
------------------------------------------------------------------------
American Lebanese              $10,000   St. Jude Gourmet Gala
 Syrian Associated
 Charities, Inc.
------------------------------------------------------------------------
National Kidney                 $1,000   Champion of Hope Tribute Dinner
 Foundation of
 Michigan
------------------------------------------------------------------------
National Congressional         $25,000   Gold Membership
 Award Foundation
------------------------------------------------------------------------
Research!America               $25,000   20th Annual Advocacy Awards
                                          Dinner
------------------------------------------------------------------------
Society for Women's            $10,000   2016 SWHR Annual Gala Dinner
 Health Research
------------------------------------------------------------------------
American Cancer                 $2,500   Relay For Life of Bridgewater
 Society Cancer Action
 Network
------------------------------------------------------------------------
University of Arizona           $3,000   Sponsorship of the 28th Annual
 Foundation                               Undergraduate Biology Research
                                          Program Conference
------------------------------------------------------------------------
Diabetes Hands                 $37,500   Online Community for People
 Foundation                               with Diabetes
------------------------------------------------------------------------
Boston University               $2,500   Boston University School of
 School of Public                         Public Health 40th Anniversary
 Health                                   Gala
------------------------------------------------------------------------
Pro Bono Partnership           $10,000   Pro Bono Partnership 2016 Gala
------------------------------------------------------------------------
Christ The King                 $5,000   8th Annual President's Gala
 Preparatory School of
 Newark NJ Corp.
------------------------------------------------------------------------
Children's Health Fund         $25,000   2016 Annual Benefit
------------------------------------------------------------------------
The Children's Aid             $25,000   The Children's Aid Society's
 Society                                  Keeping the Promise Benefit
------------------------------------------------------------------------
The American Heart              $5,000   Heart & Stroke Ball
 Association
------------------------------------------------------------------------
Good Grief Inc.                 $2,500   2016 Great Pumpkin Ball
------------------------------------------------------------------------
United Way of Northern            $500   Pathways for Caregivers 2016
 New Jersey                               Reprint
------------------------------------------------------------------------
Easterseals New Jersey          $1,350   46th Annual Raritan Valley
                                          Workshop Dinner Dance
------------------------------------------------------------------------
Safe+Sound Somerset            $10,000   Soaring to New Heights
------------------------------------------------------------------------
Deirdre O'Brien Child           $2,000   Gala Sponsorship
 Advocacy Center Inc.
------------------------------------------------------------------------
The Center For Great            $5,000   2016 Gift of Hope Gala
 Expectations Inc
------------------------------------------------------------------------
Somerset County                   $500   Second Annual Workplace Health
 Business Partnership                     & Wellness Expo 2016
------------------------------------------------------------------------
RESOURCES USA INC.              $5,000   Bastille Day 2016
------------------------------------------------------------------------
RESOURCES USA INC               $5,000   Bastille Day events
------------------------------------------------------------------------
CANCER SUPPORT                  $5,000   Inspiring Hope
 COMMUNITY CENTRAL NEW
 JERSEY
------------------------------------------------------------------------
Auxiliary of the                $5,000   57th Annual Auxiliary Autumn
 Robert Wood Johnson                      Ball
 University Hospital
------------------------------------------------------------------------
Pocono Mountains                $6,000   Pocono Mountains Community
 Community Challenge                      Fundraiser
 Fund
------------------------------------------------------------------------
The American Kidney            $50,000   2016 The Hope Affair
 Fund, Inc.
------------------------------------------------------------------------
Partnership for a               $4,500   PHA Fit to Celebrate Gala
 Healthier America
 Inc.
------------------------------------------------------------------------
American Society of            $75,000   2017 Corporate Sponsor
 Transplant Surgeons
 Foundation
------------------------------------------------------------------------
Vision y Compromiso             $5,000   Hacia Una Vida y Sana, the 13th
                                          Annual Promotoras and
                                          Community Health Workers
                                          Conference
------------------------------------------------------------------------
Turn 2 Foundation Inc.         $15,000   Turn 2 Foundation 20th Annual
                                          Dinner
------------------------------------------------------------------------
AAALAC International            $5,000   IQ/AAALAC International Global
                                          3Rs Award Program
------------------------------------------------------------------------
Asthma & Allergy                $1,000   Fall 2016 AAFA-STL Printed
 Foundation of                            Newsletter
 America, St. Louis
 Chapter
------------------------------------------------------------------------
Autoimmune Advocacy             $2,500   A Grapevine Grows
 Alliance
------------------------------------------------------------------------
Operation Warrior               $7,500   Warrior Wishes 2016 Army/Navy
 Wishes Foundation                        Game
------------------------------------------------------------------------
Washington Legal               $30,000   2016 General Operating Support
 Foundation
------------------------------------------------------------------------
Maryland Black Caucus           $2,500   Legislative Weekend
 Foundation, Inc.
------------------------------------------------------------------------
Research!America               $10,000   National Health Research Forum
------------------------------------------------------------------------
Friends of Cancer              $25,000   Friends of Cancer Research 20th
 Research                                 Anniversary Cancer Leadership
                                          Awards Dinner
------------------------------------------------------------------------
Project Hope The               $10,000   2016 Project HOPE Gala
 People To People
 Health Foundation
 Inc.
------------------------------------------------------------------------
The Virginia Public               $700   Lighten Up, It's Just Politics
 Access Project
------------------------------------------------------------------------
AMGA Foundation Inc.           $10,000   AMGA Foundation 50th
                                          Anniversary Gala
------------------------------------------------------------------------
CEO Roundtable on             $500,000   Project Data Sphere initiative
 Cancer
------------------------------------------------------------------------
Conference of Western           $5,000   CWAG 2016 Winter Dinner
 Attorneys General                        Sponsorship
------------------------------------------------------------------------
Western Governors'             $10,000   WGA Annual Contribution
 Foundation
------------------------------------------------------------------------
Colon Cancer Alliance           $3,500   2016 Blue Hope Bash
------------------------------------------------------------------------
American Statistical            $9,500   Breiamn Award
 Association
------------------------------------------------------------------------
Washington Policy               $4,000   2016 Annual Dinner
 Center
------------------------------------------------------------------------
NEHI (Network for              $75,000   Health Care Without Walls
 Excellence in Health
 Innovation)
------------------------------------------------------------------------
Cheshire Health                 $1,000   Cheshire Stepping Out for
 Foundation                               Diabetes Walk
------------------------------------------------------------------------
Massachusetts General           $5,000   The Role of Tumor
 Hospital                                 Microenvironment: a 40-year
                                          Journey
------------------------------------------------------------------------
Massachusetts General           $5,000   Massachusetts General Hospital
 Hospital                                 Immunology Seminar Series
------------------------------------------------------------------------
YMCA of Greater Boston         $10,000   YMCA's Diabetes Prevention
                                          Program
------------------------------------------------------------------------
MIT 100K                       $25,000   MIT 100K Entrepreneurship
 Entrepreneurship                         Competition
 Competition
------------------------------------------------------------------------
Joslin Diabetes                $10,000   High Hopes Gala
 Center, Inc.
------------------------------------------------------------------------
Joslin Diabetes                 $2,500   Ritmos de salud (healthy
 Center, Inc.                             rhythms)
------------------------------------------------------------------------
Multi Regional                 $50,000   Multi Regional Clinical Trials
 Clinical Trials                          Center of Brigham and Women's
 Center of Brigham and                    Hospital and Harvard
 Women's Hospital and
 Harvard
------------------------------------------------------------------------
Foundation for                 $12,500   Animal Research Communications
 Biomedical Research                      Campaign
------------------------------------------------------------------------
Foundation for                 $20,000   Public Education to Advance
 Biomedical Research                      Understanding of Animal
                                          Research
------------------------------------------------------------------------
Massachusetts Society           $2,500   The MSMR Annual Meeting of
 for Medical Research,                    Members
 Inc.
------------------------------------------------------------------------
Children's Hospital            $10,000   PCMM Retreat
 Corporation
------------------------------------------------------------------------
Foundation for                  $5,000   Scientific Symposium in honor
 Neurologic Diseases,                     Vijay K. Kuchroo
 Inc.
------------------------------------------------------------------------
Lake Norman Community           $1,000   Sunset and Sandals
 Health Clinic
------------------------------------------------------------------------
Multiple Myeloma               $50,000   Multiple Myeloma Educational
 Research Foundation                      Programming
------------------------------------------------------------------------
American Diabetes               $2,500   CNY Diabetes Community Forum
 Association Inc.
------------------------------------------------------------------------
American Diabetes               $5,000   Community Awareness Training
 Association
------------------------------------------------------------------------
American Diabetes               $2,500   Step Out Walk to Stop Diabetes--
 Association                              Phoenix
------------------------------------------------------------------------
American Diabetes               $2,500   2016 Kiss a Pig Gala
 Association
------------------------------------------------------------------------
American Diabetes               $2,500   American Diabetes Association's
 Association                              Connecticut Tour de Cure
------------------------------------------------------------------------
American Diabetes               $5,000   American Diabetes Association
 Association                              New England Classic Multi-Day
                                          Tour de Cure
------------------------------------------------------------------------
American Diabetes               $2,500   American Diabetes Association's
 Association                              Kennebunks Tour de Cure
------------------------------------------------------------------------
American Diabetes               $2,500   American Diabetes Association's
 Association                              Ocean State Tour de Cure
------------------------------------------------------------------------
American Diabetes               $2,500   American Diabetes Association's
 Association                              North Shore Tour de Cure
------------------------------------------------------------------------
American Diabetes              $10,000   ADA Indiana's Josiah Kirby
 Association, Indiana                     Lilly Sr. Distinguished
                                          Service Award Gala
------------------------------------------------------------------------
American Diabetes               $2,500   2016 Father of the Year Awards
 Association                              Dinner
------------------------------------------------------------------------
American Diabetes              $50,000   Diabetes Awareness and
 Association                              Intervention--via Step Out:
                                          Walk to Stop Diabetes, the Red
                                          Rider/Red Strider Program and
                                          the Annual Diabetes Conference
                                          in NJ
------------------------------------------------------------------------
American Diabetes               $2,500   2016 World Diabetes Day Summit
 Association
------------------------------------------------------------------------
American Diabetes              $20,000   Unmasking Diabetes Gala &
 Association                              Awards
------------------------------------------------------------------------
American Diabetes               $2,500   Step Out Walk to Stop Diabetes
 Association                              of the Triangle
------------------------------------------------------------------------
American Diabetes               $2,500   Tour De Cure + Step Out: Walk
 Association                              to Stop Diabetes
------------------------------------------------------------------------
American Diabetes               $2,500   Father of the Year Awards
 Association
------------------------------------------------------------------------
National Health               $100,000   The Patient Perspective on the
 Council                                  Value of Treatments
------------------------------------------------------------------------
National Health                $95,000   Health Technology Assessments
 Council                                  and Value: The Patient
                                          Perspective
------------------------------------------------------------------------
National Kidney                $50,000   2016 New York City Kidney Walk
 Foundation, Inc.                         and Patient Journeys
------------------------------------------------------------------------
National Kidney                $15,000   2016 Boston Kidney Walk
 Foundation
------------------------------------------------------------------------
Organization for               $15,000   2016 OFII Annual Dinner
 International
 Investment
------------------------------------------------------------------------
Healthcare                      $8,850   HBA Woman of the Year Elite
 Businesswomen's                          Table
 Association
------------------------------------------------------------------------
United States Bone and         $20,000   Burden of Musculoskeletal
 Joint Initiative, NFP                    Diseases in the United States
                                          (BMUS) Report
------------------------------------------------------------------------
United States Bone and         $80,000   Experts in Arthritis (EIA)
 Joint Initiative, NFP
------------------------------------------------------------------------
American College of           $150,000   LDL Address the Risk Think Tank
 Cardiology
------------------------------------------------------------------------
The Leukemia &                  $2,500   Lowcountry Light The Night Walk
 Lymphoma Society
------------------------------------------------------------------------
The Leukemia &                 $16,000   Light The Night Sponsorship
 Lymphoma Society
------------------------------------------------------------------------
THE LEUKEMIA &                 $50,000   Band Against Cancer: The Sarah
 LYMPHOMA SOCIETY                         Cannon Tour
------------------------------------------------------------------------
Moses E. Cheeks Slam            $2,500   Moses E. Cheeks Slam Dunk for
 Dunk for Diabetes                        Diabetes Basketball Camp
------------------------------------------------------------------------
American Foundation            $25,000   2016 Get in Rhythm. Stay in
 for Women's Health                       Rhythm. Atrial Fibrillation
 (dbaStopAfib.org)                        Patient Conference
------------------------------------------------------------------------
National Alliance of            $5,000   Advanced Prostate Cancer
 State Prostate Cancer                    Laminate
 Coalitions
------------------------------------------------------------------------
National Alliance of            $5,000   12th Annual Meeting of the
 State Prostate Cancer                    National Alliance of State
 Coalitions                               Prostate Cancer Coalitions
------------------------------------------------------------------------
Colorectal Cancer              $10,000   Guide in the Fight for Late
 Coalition Inc                            Stage CRC Patients
------------------------------------------------------------------------
Myotonic Dystrophy              $3,000   MDF Annual Conference
 Foundation
------------------------------------------------------------------------
New Jersey Association          $1,000   3Rs Sharing Conference V
 for Biomedical
 Research, Inc.
------------------------------------------------------------------------
Academy of Managed             $15,000   AMCP 2016 Partnership Forum:
 Care Pharmacy                            Enabling the Exchange of
                                          Clinical and Economic Data Pre-
                                          FDA Approval
------------------------------------------------------------------------
Academy of Managed             $18,000   AMCP Oncology Management
 Care Pharmacy                            Partnership Forum
------------------------------------------------------------------------
BIONJ INC.                     $10,000   Annual Dinner
------------------------------------------------------------------------
Community Oncology             $15,000   Oncology Care Model Filming
 Alliance
------------------------------------------------------------------------
Community Oncology              $7,500   Community Oncology Alliance CMS
 Alliance                                 Oncology Care Model Payer
                                          Session
------------------------------------------------------------------------
Community Oncology             $25,000   2016 Community Oncology Payer
 Alliance                                 Exchange Summit V Oncology
                                          Payment Reform
------------------------------------------------------------------------
JDRF International              $2,500   JDRF One Walk 2016
------------------------------------------------------------------------
JDRF                            $5,000   JDRF One Walk Pittsburgh
------------------------------------------------------------------------
JDRF                            $5,000   JDRF One Walk Westmoreland
------------------------------------------------------------------------
Juvenile Diabetes               $2,500   JDRF One Walk Rochester
 Research Foundation
------------------------------------------------------------------------
Juvenile Diabetes               $2,500   JDRF One Walk Southern Tier
 Research Foundation
------------------------------------------------------------------------
JDRF NENY                       $2,500   JDRF Saratoga One Walk
------------------------------------------------------------------------
JDRF--Western New York          $2,500   JDRF Buffalo One Walk
 Chapter
------------------------------------------------------------------------
JDRF International              $2,500   JDRF One Walk Boston 2016
------------------------------------------------------------------------
American Society of            $10,000   Mambo for Myeloma ASH
 Hematology                               Sponsorship
------------------------------------------------------------------------
The American Kidney             $5,000   2016 A Pairing For Prevention
 Fund, Inc.
------------------------------------------------------------------------
The American Kidney            $75,000   New To Dialysis Campaign
 Fund, Inc.
------------------------------------------------------------------------
THE TRANSPLANTATION            $50,000   TTS Transplantation Leadership
 SOCIETY                                  Series
------------------------------------------------------------------------
PROMIS Health                  $10,000   PROMIS: Measuring Health
 Organization (PHO)                       Outcomes Around the World
------------------------------------------------------------------------
The Foundation for              $5,000   International Research
 Peripheral Neuropathy                    Symposium/Advances in
                                          Neuropathy--Emerging Therapies
------------------------------------------------------------------------
PQA, Inc.                       $5,000   PQA Leadership Summit 2016
------------------------------------------------------------------------
PQA, Inc.                      $25,000   PQA Insulin Adherence Committee
------------------------------------------------------------------------
MMORE: Multiple                 $5,000   MoveMMORE Seattle 2016
 Myeloma Opportunities
 for Research &
 Education
------------------------------------------------------------------------
International Society           $5,000   ACoP7 meeting
 of Pharmacometrics
------------------------------------------------------------------------
The Galien Foundation          $15,000   The Galien Forum
------------------------------------------------------------------------
MassChallenge, Inc.             $4,000   2016 MC Awards
------------------------------------------------------------------------
MassChallenge, Inc.            $40,000   MassChallenge
------------------------------------------------------------------------
Alliance for                    $5,000   Cell & Gene Meeting on the Mesa
 Regenerative Medicine
------------------------------------------------------------------------
Oklahoma Center for             $3,000   Transformation of Healthcare:
 Healthcare                               CPC Learning Session
 Improvement
------------------------------------------------------------------------
Health Literacy               $225,000   The Blue Ribbon Online
 Missouri                                 Clearinghouse of Kidney
                                          Transplantation and Living
                                          Donation Resources (BROC)
------------------------------------------------------------------------
Health Literacy                $50,000   My Transplant Coach Application
 Missouri                                 Development Project
------------------------------------------------------------------------
Center for Medical             $40,000   GPC--Real World Evidence
 Technology Policy
------------------------------------------------------------------------
Center for Healthcare           $7,500   2016 Diversity, Inclusion, &
 Innovation                               Life Sciences Symposium
------------------------------------------------------------------------
BIO Ventures for               $10,000   2016 BIO International
 Global Health (BVGH)                     Convention Africa Pavilion
------------------------------------------------------------------------
National Transitions           $50,000   NTOCC Mission Support
 of Care Coalition
------------------------------------------------------------------------
The American College            $6,000   2016 ACVP/ASVCP Concurrent
 of Veterinary                            Annual Meeting
 Pathologists
------------------------------------------------------------------------
South Dakota Diabetes           $1,000   Third Annual Sweet Success
 Coalition                                Extravaganza
------------------------------------------------------------------------
T. Leroy Jefferson              $2,000   2016 Community Health Fair:
 Medical Society                          Healthy Children for a Healthy
                                          Future
------------------------------------------------------------------------
North Coast Health              $1,000   Celebration of Caring 2016
------------------------------------------------------------------------
Academy of Nutrition           $18,000   DCE On the Cutting Edge
 and Dietetics on                         newsletter
 behalf of Diabetes
 Care and Education
------------------------------------------------------------------------
America's Health               $55,000   Executive Leadership Program
 Insurance Plans
------------------------------------------------------------------------
American Liver                  $2,500   Diabetes and NASH Webinar
 Foundation
------------------------------------------------------------------------
Us TOO International            $2,500   12th Annual SEA Blue Chicago
                                          Prostate Cancer Walk & Run
------------------------------------------------------------------------
Blood and Marrow                $2,500   BMT InfoNet Resource Directory
 Transplant                               update and reprint
 Information Network
------------------------------------------------------------------------
Chicago Hispanic                $1,000   10th Annual Vive tu Vida/Get
 Health Coalition                         Up! Get Moving! Health and
                                          Wellness Fair
------------------------------------------------------------------------
The Council of State            $5,000   Bowhay Institute
 Government, Ltd.
------------------------------------------------------------------------
National Bone Marrow            $5,000   Update, Edit and Transplant
 Transplant Link                          Survivors' Guide for Bone
                                          Marrow, Stem Cell and Cord
                                          Blood Transplant
------------------------------------------------------------------------
International Society           $8,000   Corporate Membership
 for                                      Application
 Pharmacoepidemiology
------------------------------------------------------------------------
Be The Match                   $90,000   Quick Reference Guidelines--
 Foundation                               Transplant Consultation and
                                          Post-Transplant Care
------------------------------------------------------------------------
American Society of            $10,000   Meet the Faculty Networking
 Transplantation                          Session @ 2016 AST Fellows
                                          Symposium on Transplantation
------------------------------------------------------------------------
Iowa Pharmacy                  $10,000   2016 Leadership in Pharmacy
 Association                              advocacy program
 Foundation
------------------------------------------------------------------------
Mid-America Coalition           $4,000   Type 2 Diabetes in Kansas City:
 on Health Care                           A Collaborative Approach
------------------------------------------------------------------------
St. Louis Children's           $50,000   Food Allergy Management and
 Hospital Foundation                      Education (FAME)
------------------------------------------------------------------------
Missouri Biotechnology          $1,000   BIO Benchmarking Program
 Association
------------------------------------------------------------------------
Metabolic Endocrine            $25,000   14th Annual World Congress on
 Education Foundation                     Insulin Resistance Diabetes
                                          and Cardiovascular Disease
                                          (WCIRDC)
------------------------------------------------------------------------
The diaTribe                    $5,000   10th Annual Diabetes Forum
 Foundation
------------------------------------------------------------------------
Greater Philadelphia            $1,000   GPBCH Annual Wellness Summit
 Business Coalition on
 Health
------------------------------------------------------------------------
Project Access of                 $500   Diabetic Walk
 Howard County
------------------------------------------------------------------------
National Diabetes              $14,000   Access to Insulin Patient
 Volunteer Leadership                     Advocacy Study
 Council
------------------------------------------------------------------------
Keystone for                    $5,000   Foundation2016 Conference
 Incubating Innovation
 in Life sciences
 Network (KiiLN)
------------------------------------------------------------------------
ALL IN TOGETHER                $25,000   All In Together Campaign Women
 CAMPAIGN INC                             in Healthcare Policy Forum
------------------------------------------------------------------------
Washington Health               $6,600   2016 Alliance Membership
 Alliance
------------------------------------------------------------------------
IIT Association of              $2,500   2016 PanIIT Leadership
 Greater New England                      Conference
------------------------------------------------------------------------
California Life                 $7,500   2016 Life Sciences Academy
 Sciences Association
------------------------------------------------------------------------
The Kansas Chamber                $884   Corporate Membership
------------------------------------------------------------------------
Delaware Diabetes               $2,500   Delaware Diabetes Coalition
 Coalition                                2016 EXPO
------------------------------------------------------------------------
American Legislative           $10,000    Life Sciences Academy
 Exchange Council
------------------------------------------------------------------------
Biotechnology                  $10,000   ODTC White Paper
 Innovation
 Organization
------------------------------------------------------------------------
Biotechnology                  $20,000   State Policy Maker Round Tables
 Innovation                               on Value of Biopharmaceutical
 Organization (BIO)                       Industry
------------------------------------------------------------------------
American Association           $50,000   Sustaining Sponsorship
 of Pharmaceutical
 Scientists
------------------------------------------------------------------------
Society for Women's            $10,000   National Conference on Women's
 Health Research                          Health Research--Diabetes/
                                          Metabolism
------------------------------------------------------------------------
International                  $33,000   IPEC-Americas 2016 Membership
 Pharmaceutical                           Dues
 Excipients Council of
 the Americas (IPEC-
 Americas)
------------------------------------------------------------------------
FSH Society                     $2,500   FSHD Connect Conference
------------------------------------------------------------------------
International Society          $10,000   RECOMB/ISCB Conference on
 for Computational                        Regulatory and Systems
 Biology, Inc.                            Genomics with DREAM Challenges
------------------------------------------------------------------------
WomenHeart: The                $25,000   Access NOW! Campaign
 National Coalition
 for Women with Heart
 Disease
------------------------------------------------------------------------
Springboard 2000               $15,000   Health Innovation Hub
 Enterprises, Inc.
------------------------------------------------------------------------
American Cancer                 $1,000   2016 ACS CAN Michigan Forum and
 Society Cancer Action                    ACS CAN advocacy activities
 Network                                  nationwide
------------------------------------------------------------------------
APhA Foundation               $168,870   Consensus Consortium on Patient
                                          Self-Management Credentialing
                                          (PSMC) and Value-Based Health
                                          Benefit Design Considerations
                                          in Patient-Centered, Team-
                                          Based Care
------------------------------------------------------------------------
Society of Toxicology           $2,500   The Use of Cardiomyocytes for
                                          the Assessment of
                                          Proarrhythmic Risk
------------------------------------------------------------------------
Camp Holiday Trails             $2,500   Family Diabetes Camp and Summer
                                          Camperships
------------------------------------------------------------------------
Women In Government             $5,000   2016 Healthcare Summit Diabetes
 Foundation, Inc.                         Programming
------------------------------------------------------------------------
Women In Government            $20,000   Diabetes Campaign--Phase II
 Foundation, Inc.
------------------------------------------------------------------------
Patient Advocate               $35,000   Understanding What Patients
 Foundation                               Value and What and Matters to
                                          Them During Their Treatment:
                                          The Prostate Cancer Research
                                          Program (PCRP)
------------------------------------------------------------------------
Organ Donation and              $4,500   National Critical Issues Forum
 Transplantation
 Alliance
------------------------------------------------------------------------
Arthritis Foundation,          $40,000   ICER Survey
 Inc.
------------------------------------------------------------------------
Georgia Life Sciences           $1,500   Georgia Life Sciences Coalition
 Coalition
------------------------------------------------------------------------
International Cytokine         $15,000   4TH ANNUAL MEETING OF THE
 and Interferon                           INTERNATIONAL CYTOKINE AND
 Society Inc.                             INTERFERON SOCIETY (ICIS)
------------------------------------------------------------------------
American Association           $25,000   AACE Diabetes Resource Center,
 of Clinical                              2016-17
 Endocrinologists
------------------------------------------------------------------------
ZERO--The End of                $5,000   ZERO Prostate Cancer Community
 Prostate Cancer                          Advocacy Events
------------------------------------------------------------------------
The Diabetes Coalition          $2,500   Giving Diabetes the Blues
 of Mississippi/
 Mississippi Rural
 Health Association
------------------------------------------------------------------------
University of Southern          $5,000   National Unity 2016 Conference:
 Mississippi                              Community Health Workers -
 Foundation                               Social Change Agents Advancing
                                          Health Equity and Improving
                                          Outcomes
------------------------------------------------------------------------
NBCH                           $25,000   High Value Health: Making the
                                          Dream a Reality
------------------------------------------------------------------------
Fundacion Centro                $5,000   World Diabetes Month
 Pediatrico de                            Celebration 2016
 Diabetes
------------------------------------------------------------------------
Fundacion Centro                $3,500   XV Annual Gala Dinner
 Pediatrico de
 Diabetes
------------------------------------------------------------------------
TULANE CANCER CENTER            $1,000   NOLA Bluedoo Run/Walk
------------------------------------------------------------------------
NCSL Foundation for             $7,500   NCSL LegisBrief Sponsorship
 State Legislatures
------------------------------------------------------------------------
Arizona Diabetes                $2,500   Arizona Diabetes Foundation
 Foundation
------------------------------------------------------------------------
Federation of Clinical         $10,000   FOCIS 2016 Annual Meeting
 Immunology Societies
------------------------------------------------------------------------
Society of Dermatology         $30,000   SDPA 14th Annual Fall
 Physician Assistants                     Dermatology Conference
------------------------------------------------------------------------
Colon Cancer Alliance          $10,000   2016 Live Your Best Life mCRC
                                          Patient Symposium
------------------------------------------------------------------------
National Eczema               $100,000   Leaders in Eczema Forum Series
 Association
------------------------------------------------------------------------
Congress of California          $1,500   Script Your Future Senior
 Seniors Education and                    Leader Education
 Research Fund
------------------------------------------------------------------------
Association of Black           $20,000   Improving Access to Innovative
 Cardiologists                            Therapies in High-Risk
                                          Populations
------------------------------------------------------------------------
Lymphoma Research               $3,000   Understanding Transplantation
 Foundation                               and Lymphoma Patient Guide
------------------------------------------------------------------------
Prostate Cancer               $250,000   23rd Annual Scientific Retreat
 Foundation
------------------------------------------------------------------------
                            $8,708,932
Product Donations made
 by Sanofi US to the
 Sanofi Foundation for
 North America *
 (estimate)
                          $343,602,000
------------------------------------------------------------------------


        Donations made by the Sanofi Foundation for North America
------------------------------------------------------------------------
      Legal Name         Payment Amount           Project Title
------------------------------------------------------------------------
Trustees of Boston            $125,000   National CHW Association
 University
------------------------------------------------------------------------
Tufts Center for the           $12,500   Assessing the Use of Real World
 Study of Drug                            Evidence to Support Regulated
 Development                              Medical Research and Post-
                                          Marketing Safety Monitoring
------------------------------------------------------------------------
Cambridge Arts Council          $5,000   2016 Summer Programs for
 Fund                                     Magazine Beach Park
------------------------------------------------------------------------
Americares                     $25,000   Disaster Relief--Hurricane
                                          Matthew
------------------------------------------------------------------------
Americares                      $5,000   AmeriCares Airlift Benefit
------------------------------------------------------------------------
Americares                     $25,000   Ecuador Earthquake Response
------------------------------------------------------------------------
Americares                     $10,000   U.S. Disaster Assistance
------------------------------------------------------------------------
Christ The King                $59,000   Corporate Work Study Program
 Preparatory School of
 Newark NJ Corp
------------------------------------------------------------------------
NAACP                          $10,000   Childhood Obesity
------------------------------------------------------------------------
AMERICAN DIABETES           $2,500,000   Pathway to Stop Diabetes
 ASSOCIATION INC
------------------------------------------------------------------------
National Kidney                 $5,000   New Jersey Kidney Transplant
 Foundation, Inc.                         Workshop
------------------------------------------------------------------------
March of Dimes                 $86,000   Supporting NICU Babies and
 Foundation                               Families
------------------------------------------------------------------------
Heritage of Pride,              $2,899   NYC Pride March
 Inc.
------------------------------------------------------------------------
Children's Health Fund          $5,000   Baton Rouge--Emergency Response
------------------------------------------------------------------------
The Salvation Army             $10,000   Healthy Food Pantry Program
------------------------------------------------------------------------
Columbia Univeristy           $100,000   Project on Non-Communicable
 Mailman School of                        Diseases
 Public Health
------------------------------------------------------------------------
THE LEUKEMIA &                 $19,640   Fiscal Year 2017 Myeloma
 LYMPHOMA SOCIETY                         Patient Education
------------------------------------------------------------------------
Stop Hunger Now Inc.           $10,000   Stop Hunger Now Disaster Ready
                                          Response
------------------------------------------------------------------------
Garden State Equality           $5,000   Pledge and Protect LGBT Seniors
 Education Fund Inc.
------------------------------------------------------------------------
Camp Nejeda Foundation         $10,000   Camp Nejeda: Helping Kids with
                                          Type 1 Diabetes Live Happier,
                                          Healthier Lives
------------------------------------------------------------------------
Matheny School and             $10,000   Matheny Center of Medicine and
 Hospital Inc.                            Dentistry
------------------------------------------------------------------------
United Way of Northern        $100,000   Caregivers Coalition
 New Jersey
------------------------------------------------------------------------
Jersey Battered                 $5,000   Community Counseling Services
 Women's Service, Inc.
------------------------------------------------------------------------
Food Bank of Somerset          $10,000   Back Pack Program
 County Inc.
------------------------------------------------------------------------
Community Hope, Inc.           $25,000   Residential Recovery Programs
                                          for Homeless Veterans and
                                          Disabled Individuals
------------------------------------------------------------------------
Hyacinth Foundation, A         $15,000   Hyacinth Psychosocial Support
 New Jersey Non-profit                    Services
 Corporation
------------------------------------------------------------------------
Kean University                $15,000   2016 Group Summer Scholars
 Foundation Inc                           Research Program
------------------------------------------------------------------------
Visiting Nurse                 $10,000   Hospice Care and Adult Day Club
 Association of                           Services
 Somerset Hills
------------------------------------------------------------------------
NJ SEEDS                       $10,000   Young Scholars Program--Health
                                          Sessions
------------------------------------------------------------------------
Somerset Health Care           $30,000   Fun n' Fit
 Foundation
------------------------------------------------------------------------
Somerset Health Care            $5,000   Quality CPR Saves Lives
 Foundation
------------------------------------------------------------------------
Somerset Health Care           $10,000   El poder
 Foundation
------------------------------------------------------------------------
Deirdre O'Brien Child          $10,000   Clinical Counseling
 Advocacy Center Inc
------------------------------------------------------------------------
Midland Adult Services         $10,000   Midland Helping Hands
 Inc                                      Employment Training Program
                                          and Midland Meals on Wheels
                                          Employment Training Program
------------------------------------------------------------------------
The Center For Great           $10,000   Adult Women & their Children
 Expectations Inc.
------------------------------------------------------------------------
Dress For Success              $10,000   Dress for Success Morris County
 Morris County Inc.                       Transforming Lives Gala
------------------------------------------------------------------------
Dress For Success              $10,000   FOUNDATIONS OF SUCCESS
 Morris County Inc.                       WORKSHOPS
------------------------------------------------------------------------
The Partnership for            $10,000   Community of Practice
 Quality Medical
 Donations
------------------------------------------------------------------------
Raritan Valley                  $3,000   College Campus Experience Day
 Community College                        for STEM High School Students
 Foundation
------------------------------------------------------------------------
Raritan Valley                 $10,000   Preparing for the Next
 Community College                        Generation Science Standards
 Foundation
------------------------------------------------------------------------
Raritan Valley                  $7,500   Galileo Scholarships: Expanding
 Community College                        Access to STEM Education
 Foundation
------------------------------------------------------------------------
Rutgers University             $10,000   Vets4Warriors
 Foundation
------------------------------------------------------------------------
The American Fallen            $15,000   Portrait Sponsorship
 Soldiers Project Inc.
------------------------------------------------------------------------
Strengthen Orlando d/b/         $5,000   OneOrlando Fund
 a OneOrlando Fund
------------------------------------------------------------------------
Alliance For A                 $25,000   America's Healthiest Schools
 Healthier Generation
 Inc.
------------------------------------------------------------------------
Diabetes Scholars              $10,000   Diabetes Scholars Foundation
 Foundation                               College Scholarships
------------------------------------------------------------------------
Map International              $10,000   US Disaster Relief
------------------------------------------------------------------------
Head and Neck Cancer            $1,000   Research on Xerostomia in HNC
 Alliance                                 patients
------------------------------------------------------------------------
United States Soccer           $10,000   Soccer for Success--Camden
 Federation Foundation
 Inc.
------------------------------------------------------------------------
Camp Quality USA dba           $10,000   Camp Quality NJ
 Camp Quality NJ
------------------------------------------------------------------------
Operation Warrior               $5,000   Warrior Wishes 2016 Mission
 Wishes Foundation
------------------------------------------------------------------------
National Transitions           $25,000   NTOCC Program Support
 of Care Foundation
------------------------------------------------------------------------
Sheltered Yoga                  $5,000   Sheltered Yoga Curriculum and
                                          Programming
------------------------------------------------------------------------
Dare to Dream Ranch             $1,000   The Dare to Dream Ranch
------------------------------------------------------------------------
Provention Health             $106,790   LDL Management Forum
 Foundation Inc.
------------------------------------------------------------------------
Heart To Heart                 $50,000   Hurricane Matthew Response
 International Inc.
------------------------------------------------------------------------
Heart To Heart                  $5,000   Louisiana Flood Reponse
 International Inc.
------------------------------------------------------------------------
Heart To Heart                 $10,000   U.S. Disaster Relief
 International Inc.
------------------------------------------------------------------------
American Society for            $1,265   General Operating Support
 Blood and Marrow
 Transplantation
------------------------------------------------------------------------
Pharmaceutical                $270,000   PhRMA Foundation Grants &
 Research and                             Fellowships
 Manufacturers of
 America Foundation
------------------------------------------------------------------------
Georgetown University         $100,000   Health Promotion and Chronic
                                          Illness: An Educational
                                          Approach
------------------------------------------------------------------------
Patient Advocate              $550,000   Metastatic Prostate &
 Foundation                               Metastatic CRC Fund
------------------------------------------------------------------------
University of North            $20,000   Pharmacoepidemiology Program
 Carolina at Chapel
 Hill
------------------------------------------------------------------------
United Way of Greater          $23,226   2016 Merial United Way Campaign
 Atlanta                                  Sanofi Foundation Match
------------------------------------------------------------------------
United Way of Greater          $24,000   Merial 2016 UW Campaign Match
 Atlanta
------------------------------------------------------------------------
UNITED WAY OF                   $5,000   Merial 2016 UW Campaign Match
 NORTHEAST GEORGIA
 INC.
------------------------------------------------------------------------
UNITED WAY OF                   $5,000   Merial Athens 2015 UW Campaign
 NORTHEAST GEORGIA INC                    Match
------------------------------------------------------------------------
UNITED WAY OF HALL              $4,000   2016 Merial United Way Campaign
 COUNTY INC.                              Sanofi Foundation Match
------------------------------------------------------------------------
UNITED WAY OF HALL              $3,615   2015 Merial United Way Campaign
 COUNTY INC.
------------------------------------------------------------------------
University of Arizona           $5,000   Applied Biosciences Graduate
 Foundation for the                       Interdisciplinary Programs
 benefit of GIDP                          Merit Scholarship
------------------------------------------------------------------------
Direct Relief                  $25,000   Hurricane Matthew Response in
                                          Haiti
------------------------------------------------------------------------
Direct Relief                   $5,000   Louisiana Flood Response
------------------------------------------------------------------------
Cancer Support                  $8,000   Bringing Multiple Myeloma
 Community                                Journey Partners to the Cancer
                                          Support Community
------------------------------------------------------------------------
Partners in Research           $25,000   Sanofi Biogenius Canada
 Canada
------------------------------------------------------------------------
Sanofi US Matching            $116,524   Sanofi US Matching Gifts--Q4
 Gifts--2015                              (December) 2015 Match
------------------------------------------------------------------------
Tufts Medical Center           $35,000   CEVR Database Subscription
------------------------------------------------------------------------
Multiple Myeloma               $19,640   Mambo for Myeloma
 Research Foundation
------------------------------------------------------------------------
Children's Health Fund         $25,000   Flint Emergency Response & Long
                                          Term Need
------------------------------------------------------------------------
Children's Health Fund        $665,000   Medical Home Initiative
------------------------------------------------------------------------
Volunteers of America           $5,000   Agape House
 Delaware Valley
------------------------------------------------------------------------
Cancer Support                 $15,000   School-Based Support Groups
 Community Central New
 Jersey
------------------------------------------------------------------------
Trustees of the                $20,000   Research Training in
 University of                            Pharmacoepidemiology
 Pennsylvania
------------------------------------------------------------------------
Foundation Fighting           $100,000   Supporting Research to Find
 Blindness                                Preventions, Treatments and
                                          Cures for Retinal Diseases
------------------------------------------------------------------------
Raritan Valley                 $15,000   Galileo Scholarships: Providing
 Community College                        Access to STEM Education
 Foundation
------------------------------------------------------------------------
Raritan Valley                 $10,000   Preparing for the Next
 Community College                        Generation Science Standards
 Foundation
------------------------------------------------------------------------
Arbor Day Foundation            $5,305   Trees in Celebration-Green
                                          Printing Initiative
------------------------------------------------------------------------
Rutgers University            $125,000   Health Outcomes, Policy, and
 Foundation                               Economics
------------------------------------------------------------------------
Arrow Lake Foundation         $146,722   General Mission Support
------------------------------------------------------------------------
Bill, Hillary, and             $50,000   National Health Transformation
 Chelsea Clinton
 Foundation
------------------------------------------------------------------------
Regents of the                 $25,000   V-BID
 University of
 Michigan
------------------------------------------------------------------------
The Medical College of          $1,265   CIBMTR General Operating
 Wisconsin, Inc.                          Support
------------------------------------------------------------------------
ALL IN TOGETHER                $37,500   All in Together Campaign:
 CAMPAIGN INC.                            Advancing and Empowering Women
                                          Leaders
------------------------------------------------------------------------
Childrens Inn at NIH          $500,000   Sanofi US Legacy Endowment Fund
 Inc.                                     at The Children's Inn at NIH
------------------------------------------------------------------------
Kids Corporation II            $10,000   Kids Corp General Operating
------------------------------------------------------------------------
American Cancer                $25,000   Nationwide Hope Lodge
 Society Cancer Action                    Partnership
 Network
------------------------------------------------------------------------
Boy Scouts of America,          $1,000   STEM Scouts, BSA
 Catalina Council
------------------------------------------------------------------------
Kino Learning Center            $2,000   STEM Funding
 Inc.
------------------------------------------------------------------------
SARSEF-SOUTHERN                 $5,000   Finding the Next Generation of
 ARIZONA RESEARCH                         STEM Researchers
 SCIENCE AND
 ENGINEERING
 FOUNDATION
------------------------------------------------------------------------
International Myeloma          $19,640   International Myeloma
 Foundation                               Foundation Mission Support
------------------------------------------------------------------------
International Myeloma           $2,000   MMJP Donation to Support the
 Foundation                               International Myeloma
                                          Foundation
------------------------------------------------------------------------
                            $6,715,031
 
    Total 2016 Sanofi     $352,310,932
     US
------------------------------------------------------------------------


                    Payments made by Sanofi US (2017)
------------------------------------------------------------------------
      Legal Name         Payment Amount            Project Title
------------------------------------------------------------------------
AAALAC International          $2,500.00   IQ Consortium/AAALAC
                                           International Global 3Rs
                                           Awards Program
------------------------------------------------------------------------
Academy of Managed           $30,000.00   2017 AMCP Partnership Forums
 Care Pharmacy
------------------------------------------------------------------------
Academy of Nutrition         $18,000.00   DCE On the Cutting Edge
 and Dietetics on                          newsletter
 behalf of Diabetes
 Care and Education
------------------------------------------------------------------------
ALL IN TOGETHER              $25,000.00   National Women's Leadership
 CAMPAIGN INC.                             Initiative
------------------------------------------------------------------------
Alliance for Patient        $150,000.00   Keep My Rx Campaign
 Access
------------------------------------------------------------------------
Alliance for the             $50,000.00   Webinars on Nonmedical
 Adoption of                               Switching of Diabetes
 Innovations in                            Patients
 Medicine (Aimed
 Alliance)
------------------------------------------------------------------------
Alliance for the             $42,000.00   Campaign to End Nonmedical
 Adoption of                               Switching of Diabetes
 Innovations in                            Patients
 Medicine (Aimed
 Alliance)
------------------------------------------------------------------------
American Academy of         $250,000.00   Practice Management Center
 Dermatology Inc
------------------------------------------------------------------------
American Association         $25,000.00   AACE 26th Annual Scientific &
 of Clinical                               Clinical Congress General
 Endocrinologists                          Support
------------------------------------------------------------------------
American Association        $150,035.00   AACE Multi-Site Proposal to
 of Clinical                               Extend the
 Endocrinologists                          Transculturalization of
                                           Diabetes Care
------------------------------------------------------------------------
American Association         $75,000.00   AADE Access and Affordability
 of Diabetes                               Forum
 Educators
------------------------------------------------------------------------
American Association         $20,000.00   2017 Public Policy Forum
 of Diabetes
 Educators
------------------------------------------------------------------------
American Cancer               $2,500.00   RUN FOR DAD
 Society
------------------------------------------------------------------------
American Cancer              $10,000.00   ACS CAN State Government
 Society Cancer                            Relations Director Training
 Action Network                            and Advocacy Activities
                                           Nationwide
------------------------------------------------------------------------
American Cancer              $25,000.00   2017 ACS CAN Fundraising
 Society Cancer                            Events and ACS CAN advocacy
 Action Network                            activities
------------------------------------------------------------------------
American Cancer               $2,500.00   Relay For Life of Bridgewater
 Society Inc.
------------------------------------------------------------------------
American Chemical             $3,000.00   Division of Medicinal
 Society Division of                       Chemistry Program 253rd ACS
 Medicinal Chemistry                       national meeting
------------------------------------------------------------------------
American Chemical             $2,500.00   ACS MEDI-EFMC Frontiers in
 Society Division of                       Medicinal Chemistry 2017
 Medicinal Chemistry
------------------------------------------------------------------------
American Chemical             $3,000.00   Division of Medicinal
 Society Division of                       Chemistry Program 254th ACS
 Medicinal Chemistry                       National Meeting
------------------------------------------------------------------------
American College of         $100,000.00   Heart House Roundtable:
 Cardiology                                Effective Prior Authorization
 Foundation
------------------------------------------------------------------------
American College of         $100,000.00   ACC's 2017 LDL: Address the
 Cardiology                                Risk Think Tank
 Foundation
------------------------------------------------------------------------
American College of          $20,000.00   Donald C. Jones Leadership and
 Endocrinology                             Endocrine Excellence Award
------------------------------------------------------------------------
American College of           $2,000.00   Expand the body of knowledge
 Laboratory Animal                         in the fields of laboratory
 Medicine                                  animal science and medicine
------------------------------------------------------------------------
American College of           $1,500.00   2017 ACT Corporate Membership
 Toxicology
------------------------------------------------------------------------
American Diabetes             $2,500.00   Tour de Cure Hawaii--Hele On
 Association                               Hawaii
------------------------------------------------------------------------
American Diabetes             $2,500.00   American Diabetes Month--
 Association                               Malama Ohana
------------------------------------------------------------------------
American Diabetes             $2,500.00   2017 RVA Tour de Cure &
 Association                               Fitness Walk
------------------------------------------------------------------------
AMERICAN DIABETES         $2,000,000.00   Pathway to Stop Diabetes
 ASSOCIATION INC.
------------------------------------------------------------------------
American Drug                $20,000.00   American Drug Utilization
 Utilization Review                        Review Symposium
 Society
------------------------------------------------------------------------
American Foundation          $25,000.00   2017 Get in Rhythm. Stay in
 for Women's Health                        Rhythm. Atrial Fibrillation
 (dba StopAfib.org)                        Patient Conference
------------------------------------------------------------------------
American Friends of          $15,000.00   Scholarship Fundraising Event--
 Toulouse School of                        Toulouse School of Economics
 Economics Inc                             Gala Event
------------------------------------------------------------------------
American Heart               $25,000.00   2017 National Health Tech &
 Association                               Innovation Forum
------------------------------------------------------------------------
American Heart               $30,000.00   Boston Heart & Stroke Ball
 Association                               Sponsor
------------------------------------------------------------------------
American Heart               $15,000.00   Heart Innovation Forum
 Association Inc
------------------------------------------------------------------------
American Medical             $50,000.00   AMSSM Research Grant Awards
 Society for Sports                        Program
 Medicine Foundation,
 Inc.
------------------------------------------------------------------------
American Medical             $25,000.00   Multi-Site CRN OA Grant with
 Society for Sports                        Shark Tank competition
 Medicine Foundation,
 Inc.
------------------------------------------------------------------------
American Orthopaedic         $55,000.00    Early Osteoarthritis and
 Society for Sports                        Prevention of OA Progression
 Medicine
------------------------------------------------------------------------
American Pharmacists         $75,000.00    Osteoarthritis Pharmacist-
 Association                               Patient Companion Guide
------------------------------------------------------------------------
American Pharmacists         $80,000.00   Osteoarthritis Pharmacist Quiz
 Association                               Platform
------------------------------------------------------------------------
American Society for         $10,000.00   4th Annual ASBMT Fall Clinical
 Blood and Marrow                          Education Conference
 Transplantation
------------------------------------------------------------------------
American Society for          $2,500.00   ASN Annual Meeting
 Neurochemistry
------------------------------------------------------------------------
American Society for          $1,500.00   Myelin Satellite Meeting
 Neurochemistry
------------------------------------------------------------------------
American Society for         $70,000.00   2017 Town Hall Presentation
 Preventive                                Series
 Cardiology
------------------------------------------------------------------------
American Society of          $35,000.00   Kidney Week 2017--Sponsorships
 Nephrology
------------------------------------------------------------------------
American Society of          $75,000.00   2018 Corporate Sponsor
 Transplant Surgeons
 Foundation
------------------------------------------------------------------------
American Statistical          $1,000.00   ASA Princeton-Trenton chapter
 Association of                            2017 Spring Symposium
 Princeton-Trenton
 Chapter
------------------------------------------------------------------------
Americans for Medical         $7,500.00   Raising Voices, Saving Lives
 Progress Educational
 Foundation
------------------------------------------------------------------------
Americares                   $12,000.00   Air Lift Benefit Sponsorship
                                           2017
------------------------------------------------------------------------
Americares                   $70,000.00   Sanofi Solar Power Puerto Rico
                                           Concept
------------------------------------------------------------------------
AMGA Foundation Inc         $175,000.00   Together 2 Goal diabetes
                                           campaign
------------------------------------------------------------------------
Amigos Together For           $5,000.00   Domino Night Gala for After
 Kids, Inc. d/b/a                          School Program, Nurturing
 Amigos For Kids                           Parent Program and Blue
                                           Ribbon Campaign
------------------------------------------------------------------------
Arizona Diabetes              $3,000.00   Diabetes: A Prescription for
 Foundation                                Care
------------------------------------------------------------------------
Arkansas Pharmacy             $1,000.00   Immunization Summit
 Foundation
------------------------------------------------------------------------
Arthritis Foundation          $1,200.00   2017 Delaware Bone Bash
------------------------------------------------------------------------
Asian American Legal         $10,000.00   2017 Justice in Action Awards
 Defense and                               Gala
 Education Fund
------------------------------------------------------------------------
Association of                $7,500.00   Sponsorship of Health
 American Medical                          Workforce Research Conference
 Colleges
------------------------------------------------------------------------
Association of Black         $25,000.00   Improving Healthcare Access
 Cardiologists                             for Minority and High Risk
                                           Population Gala Dinner
------------------------------------------------------------------------
Association of Black        $100,000.00   ABC Advocacy Training Program
 Cardiologists
------------------------------------------------------------------------
Association of                $5,000.00   AUTM 2017 Annual Meeting
 University                                Sponsorship
 Technology Managers
 Inc.
------------------------------------------------------------------------
Asthma & Allergy              $1,000.00   Asthma Coalition Meeting
 Foundation of
 America, St. Louis
 Chapter
------------------------------------------------------------------------
Austin Black                  $2,500.00   Austin Black Physicians
 Physicians                                Association Scholarship
 Association                               Fundraiser
------------------------------------------------------------------------
Autoimmune Advocacy           $2,500.00   Living with Autoimmunity
 Alliance
------------------------------------------------------------------------
Be The Match                 $37,500.00   Be The Match Walk+Run National
 Foundation                                Sponsorship
------------------------------------------------------------------------
Biocom                       $10,000.00   Global Life Science Partnering
                                           Conference
------------------------------------------------------------------------
BIONJ INC.                   $10,000.00   2017 Annual Dinner Meeting
------------------------------------------------------------------------
BIONJ INC.                    $2,500.00   2017 bioNJ BioPartnering
                                           Conference
------------------------------------------------------------------------
Biotechnology               $195,000.00   2017 BIO International
 Innovation                                Convention Sponsorship
 Organization
------------------------------------------------------------------------
Biotechnology                $25,000.00   2017 BIO Europe Spring
 Innovation                                Sponsorship
 Organization
------------------------------------------------------------------------
Biotechnology                $25,000.00   2017 BIO Europe Sponsorship--
 Innovation                                November
 Organization
------------------------------------------------------------------------
Biotechnology                $10,000.00   2017 BIO Patient and Health
 Innovation                                Advocacy Summit
 Organization
------------------------------------------------------------------------
Biotechnology                $57,500.00   2018 BIO International
 Innovation                                Convention
 Organization
------------------------------------------------------------------------
Blood and Marrow             $25,000.00   Celebrating a Second Chance at
 Transplant                                Life 2017 Survivorship
 Information Network                       Symposium
------------------------------------------------------------------------
Brigham and Women's           $2,000.00   PKD symposium
 Hospital
------------------------------------------------------------------------
Cancer Support                $8,000.00   Bringing Multiple Myeloma
 Community                                 Journey Partners to the
                                           Cancer Support Community
------------------------------------------------------------------------
CANCER SUPPORT                $5,000.00   2017 Wings of Hope
 COMMUNITY CENTRAL
 NEW JERSEY
------------------------------------------------------------------------
CANCER SUPPORT                $2,500.00   Inspiring Hope Advocate
 COMMUNITY CENTRAL                         Sponsorship
 NEW JERSEY
------------------------------------------------------------------------
CASSS                         $2,500.00   6th International Symposium on
                                           Higher Order Structure of
                                           Protein Therapeutics (HOS
                                           2017)
------------------------------------------------------------------------
CASSS                         $2,500.00   WCBP 2017: 21st Symposium on
                                           the Interface of Regulatory
                                           and Analytical Sciences for
                                           Biotechnology Health Products
------------------------------------------------------------------------
CASSS                         $2,500.00   Advances in the Biotechnology
                                           & Pharmaceutical Industries:
                                           19th Symposium on the
                                           Practical Applications for
                                           the Analysis of Proteins,
                                           Nucleotides and Small
                                           Molecules
------------------------------------------------------------------------
CASSS                         $2,500.00   14th Symposium on the
                                           Practical Application of Mass
                                           Spectrometry in the
                                           Biotechnology Industry
------------------------------------------------------------------------
CASSS                         $2,500.00   Analytical Technologies in the
                                           Biopharmaceutical Industry
                                           (AT Europe 2017)
------------------------------------------------------------------------
CASSS                         $2,500.00   Bioassays 2017
------------------------------------------------------------------------
Catalyst Inc.                $13,500.00   Catalyst International Women's
                                           Day Gala Dinner
------------------------------------------------------------------------
Chicago Hispanic                $500.00   Vive tu Vida!Get up! Get
 Health Coalition                          moving! Health and Wellness
                                           Fair
------------------------------------------------------------------------
Children's Health            $30,000.00   Children's Health Fund 2017
 Fund                                      Annual Benefit
------------------------------------------------------------------------
Children's Health           $665,000.00   Medical Home Initiative
 Fund
------------------------------------------------------------------------
Children's Health           $665,000.00   Medical Home Initiative
 Fund
------------------------------------------------------------------------
Children's Hospital          $10,000.00   2017 PCMM Scientific Retreat
 Corporation
------------------------------------------------------------------------
Children's Hospital             $500.00   Boston Postdoctoral
 Corporation                               Association Symposium on
                                           Careers and Collaboration in
                                           Science
------------------------------------------------------------------------
Christ the King               $5,000.00   Annual President's Gala
 Preparatory School
 of Newark NJ Corp
------------------------------------------------------------------------
CISCRP                       $25,000.00   AWARE for All: Clinical
                                           Research Education Day
------------------------------------------------------------------------
CISCRP                      $160,000.00   AWARE for All Campaign
------------------------------------------------------------------------
Coalition for                 $5,000.00   Health RX: Building
 Affordable Health                         Affordability & Access event
 Coverage                                  sponsorship
------------------------------------------------------------------------
Coastal Volunteers in         $1,000.00   Care & Management of Diabetic
 Medicine                                  Patients
------------------------------------------------------------------------
Cold Spring Harbor           $15,000.00   Cold Spring Harbor Laboratory
 Laboratory                                Corporate Sponsor Program
                                           2017
------------------------------------------------------------------------
College Diabetes             $55,000.00   CDN Political Advocacy for
 Network Inc.                              Young Adults Guide
------------------------------------------------------------------------
College Diabetes             $20,000.00   2017 Corporate Membership
 Network Inc.
------------------------------------------------------------------------
Colorado Business             $7,000.00   Corporate Membership
 Group on Health
------------------------------------------------------------------------
Community Health              $2,500.00   ``Patient-Centered and
 Coalition, Inc.                           Population Health for Us''
------------------------------------------------------------------------
Community Health Task           $500.00   2017 World Diabetes Day 5th
 Force, Inc.                               Annual BridgeWalk for
                                           Diabetes Awareness and Care
------------------------------------------------------------------------
Community Hope, Inc.          $4,800.00   Veterans Pre-Holiday Dinner
                                           and Gift Cards
------------------------------------------------------------------------
Community Hope, Inc.         $10,000.00   2017 Corporate Partner Program
------------------------------------------------------------------------
Community Oncology           $25,000.00   2017 Payer Exchange Summit VII
 Alliance
------------------------------------------------------------------------
Conference of Western         $5,000.00   CWAG 2017 Chair Initiative
 Attorneys General                         Sponsorship
------------------------------------------------------------------------
Congress of                   $2,500.00   Adherence Outreach and
 California Seniors                        Education with Seniors =
 Education and                             Script your Future
 Research Fund
------------------------------------------------------------------------
Council for the              $60,000.00   10th World Conference of
 Advancement of                            Science Journalists
 Science Writing,
 Inc.
------------------------------------------------------------------------
CrowdCare Foundation,        $20,000.00   Muscles for Myeloma
 Inc.
------------------------------------------------------------------------
CSweetener                   $25,000.00   CSweetener Mentoring Program
------------------------------------------------------------------------
Deep South Cancer             $5,000.00   Cycliad 2017
 Foundation
------------------------------------------------------------------------
Deirdre O'Brien Child         $5,000.00   21st Annual Gala Solicitation
 Advocacy Center Inc.
------------------------------------------------------------------------
Diabetes Foundation           $1,000.00   Tastings & Tapas Fundraiser
 Inc.
------------------------------------------------------------------------
Diabetes Foundation           $2,500.00   Live-A-Betes: Living Well with
 of Mississippi                            Diabetes
------------------------------------------------------------------------
Diversity Alliance            $5,500.00   DA4S East Coast 2017
 for Science, Inc.
------------------------------------------------------------------------
Diversity Alliance            $3,500.00   DA4S West Coast 2017
 for Science, Inc.
------------------------------------------------------------------------
Donate Life America          $26,025.00   Mission Support
------------------------------------------------------------------------
Donate Life Northwest        $10,000.00   Part II. Removing Barriers
                                           through Knowledge: An
                                           Educational Series for
                                           Providers of Dialysis and
                                           ESRD Patients
------------------------------------------------------------------------
Dress For Success            $15,000.00   Transforming Lives Celebration
 Northern New Jersey--
 10 Counties, Inc.
------------------------------------------------------------------------
Employers Health              $7,500.00   2017 Employers Health
 Coalition, Inc.                           Innovations in Employee
                                           Benefits Conference
------------------------------------------------------------------------
Endocrine Society           $150,000.00   Hypoglycemia Quality
                                           Improvement Program
------------------------------------------------------------------------
Families of SMA DBA           $5,000.00   2017 Annual SMA Conference
 Cure SMA
------------------------------------------------------------------------
Federal Circuit Bar           $2,500.00   Major Regional Program--Boston
 Association
 Charitable and
 Educational Fund
------------------------------------------------------------------------
Federation of                 $2,000.00   FASEB SRC on the Biology of
 American Societies                        Cilia and Flagella
 for Experimental
 Biology (FASEB)
------------------------------------------------------------------------
Federation of                $25,000.00   FOCIS 2017 Annual Meeting
 Clinical Immunology
 Societies
------------------------------------------------------------------------
Florida Health Care           $5,000.00   FLHCC 24th Annual National
 Coalition                                 Conference: Getting to Better
                                           Care and Improved Outcomes
------------------------------------------------------------------------
Florida International       $170,000.00   Expert Workshop State of the
 University                                Art Pertussis Prevention and
 Foundation Inc.                           Control in Latin America and
                                           the Caribbean
------------------------------------------------------------------------
Florida International        $60,000.00   LATIN AMERICAN AND CARIBBEAN
 University                                DIABETES NETWORK: A FRAMEWORK
 Foundation Inc                            FOR ACTION
------------------------------------------------------------------------
Florida International        $60,000.00   Assesment of acellular
 University                                vaccination programs in
 Foundation Inc.                           Mexico, Costa Rica and Panama
------------------------------------------------------------------------
Florida International        $25,000.00   Develop Guidelines for
 University                                Antimicrobial Stewardship For
 Foundation Inc.                           Latin America and Caribbean
                                           region
------------------------------------------------------------------------
Florida International        $62,000.00   REVIEW OF NATIONAL
 University                                IMMUNIZATION CALENDARS OF THE
 Foundation Inc.                           EXPANDED PROGRAM OF
                                           IMMUNIZATION (EPI) IN
                                           COUNTRIES OF LATIN AMERICA
                                           AND THE CARIBBEAN.
                                           PRELIMINARY OBSERVATIONS ON
                                           FINANCIAL AND FUNDING
                                           MECHANISMS OF THE NATIONAL
                                           IMMUNIZATION PROGRAMS.
------------------------------------------------------------------------
Food Allergy Research        $50,000.00   FARE Patient Registry
 & Education, Inc.
------------------------------------------------------------------------
Foundation Fighting         $100,000.00   Research to Overcome Retinal
 Blindness                                 Degenerative Diseases
------------------------------------------------------------------------
Foundation for                $7,500.00   ANIMAL RESEARCH HELPS ANIMALS
 Biomedical Research                       CAMPAIGN
------------------------------------------------------------------------
Foundation of the            $20,000.00   Foundation of the National
 National Lipid                            Lipid Association Young
 Association                               Investigator Abstract Award
                                           Program
------------------------------------------------------------------------
French-American               $2,500.00   FACC Corporate Membership
 Chamber of Commerce
 in the United
 States, Inc.--New
 York Chapter
------------------------------------------------------------------------
Friends of Cancer            $25,000.00   Exploring New Biomarkers for
 Research                                  Immunology
------------------------------------------------------------------------
Friends of Cancer            $50,000.00   2017 Mission Support
 Research
------------------------------------------------------------------------
George Washington           $130,000.00   The George Washington
 University                                University Forum on Arbovirus
                                           Infections
------------------------------------------------------------------------
GLBTQ Legal Advocates         $3,000.00   18th Annual Spirit of Justice
 & Defenders                               Award Dinner
------------------------------------------------------------------------
Good Grief Inc.               $7,500.00   2017 Golf ``Fore'' the Kids
------------------------------------------------------------------------
Good Grief Inc.               $5,000.00   Great Pumpkin Ball Sponsorship
------------------------------------------------------------------------
Gordon Research              $10,000.00   GRC: Pancreatic Diseases
 Conference                                ``Exocrine and Endocrine
                                           Pancreas: Molecules to
                                           Human''
------------------------------------------------------------------------
Gordon Research               $1,000.00   High Throughput Chemistry and
 Conference                                Chemical Biology GRC
------------------------------------------------------------------------
Gordon Research               $2,500.00   The Enduring Potential of
 Conference                                Heterocycles as Synthetic
                                           Targets, Cellular Probes, and
                                           Drug Candidates
------------------------------------------------------------------------
Gordon Research               $2,000.00   2017 Gordon Research
 Conference                                Conference on Natural
                                           Products & Bioactive
                                           Compounds
------------------------------------------------------------------------
Gordon Research               $3,000.00   2017 Gordon Research
 Conference                                Conference on Medicinal
                                           Chemistry
------------------------------------------------------------------------
Gordon Research               $3,000.00   Gordon Research Conference and
 Conference                                Seminar on ``Lysosomal
                                           Diseases''
------------------------------------------------------------------------
Gordon Research               $5,000.00   Gordon Research Conference
 Conference                                (GRC) entitled ``Neuroimmune
                                           communication in health and
                                           disease''
------------------------------------------------------------------------
Gordon Research               $5,000.00   2018 Biology of Spirochetes
 Conference                                Gordon Research Conference
                                           and Gordon Research Seminar
------------------------------------------------------------------------
Greater Detroit Area          $7,000.00   2017 GDAHC Membership Dues
 Health Council, Inc.
------------------------------------------------------------------------
Greater New England           $4,000.00   Economic Development
 Minority Supplier                         Sponsorship opportunities
 Development Council
------------------------------------------------------------------------
Health Action Council         $4,500.00   Health Action Council Annual
 Ohio                                      Event Sponsorship
------------------------------------------------------------------------
HealthCare 21                $25,000.00   Data Impact: Evaluating the
 Business Coalition                        Impact of Formulary Exclusion
                                           on Pharmacy Data
------------------------------------------------------------------------
Healthcare                    $3,000.00   2017 Woman of the Year event
 Businesswomen's
 Association
------------------------------------------------------------------------
Healthcare                   $10,000.00   2017 HBA Woman of the Year
 Businesswomen's                           event sponsorship
 Association
------------------------------------------------------------------------
Heart To Heart               $15,000.00   25th Anniversary Gala
 International Inc.
------------------------------------------------------------------------
Heart To Heart                $8,500.00   Rutgers Fellows Volunteer
 International Inc.                        Service Trip
------------------------------------------------------------------------
Hereditary Disease            $2,000.00   2017 Celebration of Discovery
 Foundation                                Symposium and Gala
------------------------------------------------------------------------
Horton's Kids, Inc.          $15,000.00   Home Runs for Horton's Kids:
                                           Comprehensive Programming for
                                           At-Risk Children
------------------------------------------------------------------------
Hunterdon Medical             $5,000.00   2017 Crystal Ball Sponsorship
 Center Foundation
------------------------------------------------------------------------
Hyacinth Foundation A         $1,000.00   Hyacinth Gala & Silent Auction
 New Jersey Nonprofit
 Corporation
------------------------------------------------------------------------
Hyacinth Foundation A         $2,500.00   Hyacinth Gala & Silent Auction
 New Jersey Nonprofit
 Corporation
------------------------------------------------------------------------
Icahn School of               $5,000.00   ISMMS-Sanofi Quantitative
 Medicine at Mount                         Systems Pharmacology
 Sinai                                     Symposium
------------------------------------------------------------------------
ILSI Health and              $99,074.00   2017 HESI Membership and
 Environmental Health                      Committee Assessments
 Institute
------------------------------------------------------------------------
Institute for Cancer         $10,000.00   2017 In Vino Vita Sponsorship
 Research dba The                          Request
 Research Institute
 of Fox Chase Cancer
 Center
------------------------------------------------------------------------
Institute for Safe            $1,000.00   20th Annual ISMP Cheers Awards
 Medication Practices
------------------------------------------------------------------------
International                 $5,000.00   NIH Oxford-Cambridge 2017
 Biomedical Research                       Global Doctoral Partnerships
 Alliance                                  Annual Workshop
------------------------------------------------------------------------
International                 $5,000.00   NIH Oxford-Cambridge 2016
 Biomedical Research                       Global Doctoral Partnerships
 Alliance                                  Annual Workshop
------------------------------------------------------------------------
International Myeloma        $50,000.00   8th International Myeloma
 Foundation                                Working Group (IMWG) Summit,
                                           Madrid, Spain
------------------------------------------------------------------------
International Myeloma        $50,000.00   2017 IMF Patient Programs
 Foundation
------------------------------------------------------------------------
International Myeloma        $50,000.00   International Myeloma
 Foundation                                Foundation 2017 Asian Myeloma
                                           Network (AMN) Summit
------------------------------------------------------------------------
Iowa Pharmacy                $10,000.00   2017 Leadership Pharmacy
 Association                               leadership training program
 Foundation
------------------------------------------------------------------------
JDRF                          $2,500.00   2017 One Walk Allentown
------------------------------------------------------------------------
JDRF                          $2,500.00   2017 One Walk Bucks County
------------------------------------------------------------------------
JDRF                          $2,500.00   2017 One Walk Reading
------------------------------------------------------------------------
JDRF                          $2,500.00   JDRF Passport to a Cure Gala
------------------------------------------------------------------------
JDRF                          $2,500.00   Rockin' Docs for Diabetes Cure
------------------------------------------------------------------------
JDRF                          $2,500.00   2017 One Walk Stroudsburg
------------------------------------------------------------------------
JDRF                          $2,500.00   2017 One Walk Moosic
------------------------------------------------------------------------
JDRF                          $2,500.00   2017 One Walk Philadelphia
------------------------------------------------------------------------
JDRF                          $1,500.00   2017 JDRF One Walk Maine
------------------------------------------------------------------------
JDRF                          $5,000.00   2017 Triangle Eastern NC
                                           OneWalk
------------------------------------------------------------------------
JDRF                         $10,000.00   2017 Triangle Eastern NC Hope
                                           Gala
------------------------------------------------------------------------
JDRF                          $5,000.00   JDRF One Promise Gala
                                           Philadelphia
------------------------------------------------------------------------
JDRF                          $5,000.00   JDRF One Walk Westmoreland
------------------------------------------------------------------------
JDRF                          $2,500.00   JDRF One Walk
------------------------------------------------------------------------
JDRF                          $5,000.00   25th Anniversary JDRF Promise
                                           Gala
------------------------------------------------------------------------
JDRF                          $2,500.00   JDRF TypeOneNation Summit
------------------------------------------------------------------------
JDRF                          $5,000.00   JDRF Imagine Gala
------------------------------------------------------------------------
JDRF--Western New             $3,000.00   Journey to A Cure Gala
 York Chapter
------------------------------------------------------------------------
JDRF--Western New             $2,500.00   Buffalo JDRF One Walk 2017
 York Chapter
------------------------------------------------------------------------
JDRF--Western New             $5,000.00   Journey to a Cure Gala
 York Chapter
------------------------------------------------------------------------
JDRF Greater Dallas           $2,500.00   JDRF One Walk, Dallas
------------------------------------------------------------------------
JDRF International            $2,500.00   JDRF One Walk 2017
------------------------------------------------------------------------
JDRF International            $5,000.00   JDRF 35th Annual Boston Gala
------------------------------------------------------------------------
JDRF INTERNATIONAL           $50,000.00   2017 JDRF Government Day
------------------------------------------------------------------------
JDRF International            $5,000.00   2017 JDRF One Walk Las Vegas
------------------------------------------------------------------------
JDRF NENY                     $2,500.00   JDRF Saratoga One Walk
------------------------------------------------------------------------
JDRF NENY                     $2,500.00   JDRF Albany One Walk
------------------------------------------------------------------------
JDRF New York City           $10,000.00   45th annual Promise Ball
 Chapter
------------------------------------------------------------------------
Jersey Battered              $14,000.00   Grand Tastings XXIII
 Women's Service,
 Inc.
------------------------------------------------------------------------
Joslin Diabetes              $10,000.00   2017 High Hopes Gala
 Center, Inc.
------------------------------------------------------------------------
Joslin Diabetes              $10,000.00   A Taste of Ginger
 Center, Inc.
------------------------------------------------------------------------
Junior Achievement of         $5,000.00   Empowering NJ Students for
 New Jersey, Inc.                          Success
------------------------------------------------------------------------
Juvenile Diabetes             $5,000.00   2018 Hope for a Cure Gala
 Research Foundation
------------------------------------------------------------------------
Juvenile Diabetes             $2,500.00   2017 JDRF One Walk Southern
 Research Foundation                       Tier
------------------------------------------------------------------------
Juvenile Diabetes             $2,500.00   2017 Hope for a Cure Gala
 Research Foundation
------------------------------------------------------------------------
Juvenile Diabetes             $2,500.00   JDRF One Walk Rochester
 Research Foundation
------------------------------------------------------------------------
Juvenile Diabetes             $2,500.00   2017 Rock the Cure
 Research Foundation
------------------------------------------------------------------------
Juvenile Diabetes             $2,500.00    One Walk, Yonkers
 Research Foundation
 International
------------------------------------------------------------------------
Keystone Symposia on         $50,000.00   Keystone Symposia Directors'
 Molecular and                             Fund
 Cellular Biology
------------------------------------------------------------------------
Keystone Symposia on         $25,000.00   Keystone Symposia Directors'
 Molecular and                             Fund
 Cellular Biology
------------------------------------------------------------------------
Lake Norman Community         $2,500.00   Sunset and Sandals
 Health Clinic
------------------------------------------------------------------------
Lymphoma Research             $2,000.00   10th Annual Love to Find a
 Foundation                                Cure Dinner
------------------------------------------------------------------------
Machestic Dragons             $5,000.00   2017 Machestic Dragons ``
                                           `Paddle for Pink' Community
                                           Dragon Boat Festival''
------------------------------------------------------------------------
Machestic Dragons               $500.00   2017 Machestic Dragons ``
                                           `Paddle for Pink' Community
                                           Dragon Boat Festival''
------------------------------------------------------------------------
Map International            $10,000.00   Bill Foege Event Sponsorship
------------------------------------------------------------------------
March of Dimes                $2,500.00   Signature Chefs--Seattle
 Foundation
------------------------------------------------------------------------
Massachusetts General         $1,500.00   18th Annual Paul S. Russell
 Hospital--Transplant                      Lecture in Transplantation
 Center
------------------------------------------------------------------------
Massachusetts                 $5,000.00   Immune Engineering Symposium
 Institute of                              2017
 Technology
------------------------------------------------------------------------
Massachusetts                 $5,000.00   Immune Engineering Symposium
 Institute of                              2017
 Technology
------------------------------------------------------------------------
Massachusetts                 $5,000.00   Koch Institute Summer
 Institute of                              Symposium 2017
 Technology
------------------------------------------------------------------------
Massachusetts Society         $1,000.00   MSMR Annual Meeting of Members
 for Medical
 Research, Inc.
------------------------------------------------------------------------
MassChallenge, Inc.          $50,000.00   PULSE@MassChallenge 2018
                                           Sanofi Gold Sponsorship
------------------------------------------------------------------------
Medical Foundation of        $10,000.00   Osteoarthritis Action Alliance
 North Carolina Inc                        (OAAA) Community mini-grant
                                           Program
------------------------------------------------------------------------
Men's Health Network         $25,000.00   Men's Health Month Sponsorship
------------------------------------------------------------------------
Mercy Health                  $2,500.00   Stick it to Diabetes
 Foundation Joplin
------------------------------------------------------------------------
Mercy Health                  $2,500.00   Mercy Gala of Hope
 Foundation--Springfi
 eld
------------------------------------------------------------------------
Metabolic Endocrine          $25,000.00   15th Annual World Congress on
 Education Foundation                      Insulin Resistance Diabetes
                                           and Cardiovascular Disease
                                           WCIRDC
------------------------------------------------------------------------
Metabolic Endocrine         $100,000.00   1st Annual Congress--Heart in
 Education Foundation                      Diabetes (HiD)
------------------------------------------------------------------------
Metabolic Endocrine          $25,000.00   15th Annual World Congress on
 Education Foundation                      Insulin Resistance Diabetes
                                           and Cardiovascular Disease--
                                           WCIRDC = Request 2
------------------------------------------------------------------------
Mid-America Coalition         $5,000.00   5th Annual Workforce &
 on Health Care                            Community Well-Being Forum
------------------------------------------------------------------------
Middle Atlantic               $1,000.00   Bradford award/student career
 Reproduction and                          event
 Teratology
 Association (MARTA)
------------------------------------------------------------------------
Moses E. Cheeks Slam          $2,500.00   Chicago Camp Slam Dunk for
 Dunk for Diabetes                         Diabetes
------------------------------------------------------------------------
Multiple Myeloma             $20,000.00   Stem Cell Care Package Program
 Research Foundation                       and Re Birthday Program
------------------------------------------------------------------------
Multiple Myeloma             $20,000.00   Multiple Myeloma Patient
 Research Foundation                       Summits
------------------------------------------------------------------------
Myotonic Dystrophy            $3,000.00   2017 MDF Conference
 Foundation                                Sponsorship
------------------------------------------------------------------------
NASPA                         $5,000.00   OA Mobility Discussion and
                                           Event
------------------------------------------------------------------------
NATIONAL ACADEMY OF          $50,000.00   Forum on Neuroscience and
 SCIENCES                                  Nervous System Disorders
------------------------------------------------------------------------
NATIONAL ACADEMY OF          $85,000.00   Forum on Drug Discovery,
 SCIENCES                                  Development and Translation
------------------------------------------------------------------------
National Alliance of         $17,000.00   Supporting Employers to
 Healthcare Purchaser                      Effectively Manage Rheumatoid
 Coalitions                                Arthritis Action Brief
------------------------------------------------------------------------
National Alliance of          $2,000.00   13th Annual Meeting of NASPCC
 State Prostate
 Cancer Coalitions
------------------------------------------------------------------------
National Bone Marrow          $5,000.00   PEER SUPPORT FOR BONE MARROW,
 Transplant Link                           STEM CELL TRANSPLANT
                                           COMMUNITY
------------------------------------------------------------------------
National Bone Marrow          $2,500.00   Resource Directory
 Transplant Link
------------------------------------------------------------------------
National Committee           $10,000.00    NCQA's Quality Talks 2017
 for Quality
 Assurance
 (``NCQA''')
------------------------------------------------------------------------
National                     $10,000.00   NCCN 12th Annual Congress:
 Comprehensive Cancer                      Hematologic Malignancies
 Network                                   Patient Advocacy Pavilion
------------------------------------------------------------------------
National Eczema              $50,000.00   National Eczema Association's
 Association                               Grassroots Advocacy Program
------------------------------------------------------------------------
National Forum for           $25,000.00   National Forum Cholesterol
 Heart Disease and                         Initiative (Phase 3)
 Stroke Prevention
 Inc.
------------------------------------------------------------------------
National Forum for           $25,000.00   National Forum Value & Access
 Heart Disease and                         Initiative
 Stroke Prevention
 Inc.
------------------------------------------------------------------------
National Health             $130,000.00   Patient Perspective on the
 Council                                   Value of Treatments
------------------------------------------------------------------------
National Hispanic             $5,000.00   Diabetes and Renal Disease
 Medical Association                       among Latino Patients
                                           Conference
------------------------------------------------------------------------
National Kidney               $1,000.00   2017 Champion of Hope Tribute
 Foundation of                             Dinner
 Michigan
------------------------------------------------------------------------
National Kidney              $50,000.00   Connecting Diabetes,
 Foundation, Inc.                          Cardiovascular Disease, and
                                           Kidney Disease `` Patient
                                           Awareness Campaign
------------------------------------------------------------------------
National Lipid               $30,000.00   Expansion of Discovering the
 Association                               Barriers to Access of PCSK9
                                           Inhibitors: an NLA Assessment
------------------------------------------------------------------------
National Minority            $25,000.00   Diabetes Working Group: Vision
 Quality Forum                             20/20
------------------------------------------------------------------------
National TB                   $5,000.00   Sponsorship for the 2017
 Controllers                               National TB Conference:
 Association                               Poster Discussion
------------------------------------------------------------------------
NCSL Foundation for           $7,500.00   NCSL LegisBrief Sponsorship
 State Legislatures
------------------------------------------------------------------------
New England                   $5,000.00   New England Immunology
 Immunology                                Conference
 Conference, Inc.
------------------------------------------------------------------------
New Jersey Public               $500.00   New Jersey Public Health
 Health Association                        Association 2017 Annual
                                           Conference
------------------------------------------------------------------------
New Jersey Society of         $5,000.00   Sponsorship/Membership
 Oncology Managers
------------------------------------------------------------------------
New York & New Jersey        $10,000.00   Annual Event Sponsorship
 Minority Supplier
 Development Council
------------------------------------------------------------------------
NewYorkBIO                    $8,000.00   NewYorkBIO 2017 Annual
                                           Conference
------------------------------------------------------------------------
NJ AIDS Services              $2,500.00   New Jersey AIDS Walk
------------------------------------------------------------------------
North Eastern Section         $2,000.00   6th Advances in Chemical
 Of American Chemical                      Sciences
 Society
------------------------------------------------------------------------
NorthCrest Medical            $2,500.00   NorthCrest Gala
 Center Foundation
------------------------------------------------------------------------
Northeast Business           $20,000.00   eValue8--Health Plan
 Group on Health                           Performance Assessment
------------------------------------------------------------------------
NYU School of                 $5,000.00   The Skirball Institute 18th
 Medicine, an                              Symposium Honoring Dan
 administrative unit                       Littman, MD
 of New York
 University
------------------------------------------------------------------------
Ohio Chamber of               $1,250.00   2017 Salt Fork Policy
 Commerce                                  Conference
------------------------------------------------------------------------
Operation Jersey                $500.00   Gala of Giving II
 Cares
------------------------------------------------------------------------
Operation Warrior            $10,000.00   2017 Army Navy Game
 Wishes Foundation
------------------------------------------------------------------------
Oregon State                  $7,500.00   OSU College of Pharmacy,
 University                                Pharmacy Partners Program
 Foundation
------------------------------------------------------------------------
Organization for             $15,000.00   2017 OFII Annual Dinner
 International
 Investment
------------------------------------------------------------------------
Out & Equal                  $25,000.00   2017 Workplace Summit
------------------------------------------------------------------------
Patient Advocate              $5,000.00   16th Annual A Promise of Hope
 Foundation                                Affair
------------------------------------------------------------------------
Patient Advocate            $250,000.00   Patient Advocate Foundation Co-
 Foundation                                Pay Relief Program Oncology
                                           Donation
------------------------------------------------------------------------
PATIENT EMPOWERMENT          $25,000.00   Virtual Town Meeting for
 NETWORK                                   Advanced Prostate Cancer
                                           Patients
------------------------------------------------------------------------
Patient Services Inc.         $5,000.00   PSI Advocacy Day and
                                           Congressional Reception
------------------------------------------------------------------------
PCMA                         $80,000.00   2017 sPCMA Business Forum
                                           Sponsorship, Presidential
------------------------------------------------------------------------
PCMA                         $95,000.00   2017 Annual Meeting
                                           Presidential Sponsorship
------------------------------------------------------------------------
Pharmaceutical              $270,000.00   PhRMA Foundation Grants &
 Research and                              Fellowships
 Manufacturers of
 America Foundation
------------------------------------------------------------------------
PQA, Inc.                     $7,500.00   PQA 2017 Leadership Summit:
                                           Connecting the Dots to
                                           Enhance Patient Care
------------------------------------------------------------------------
PQA, Inc                    $100,000.00   An Accelerated Strategy for
                                           Advancing an Insulin
                                           Adherence/Persistence Quality
                                           Measure
------------------------------------------------------------------------
Preventive                   $50,000.00   Access to Innovative Medicine
 Cardiovascular                            Campaign
 Nurses Association
------------------------------------------------------------------------
Pro Bono Partnership         $15,000.00   Pro Bono Partnership 2017 Gala
------------------------------------------------------------------------
Project Hope The             $10,000.00   2017 Gala--Project HOPE: A
 People To People                          Voice for Global Health
 Health Foundation
 Inc.
------------------------------------------------------------------------
Prostate Cancer              $10,000.00   Chemotherapy Patient Education
 Education Council
------------------------------------------------------------------------
Prostate Cancer              $25,000.00   Interactive Patient Education
 Education Council                         Programs
------------------------------------------------------------------------
Prostate Cancer             $300,000.00   24th Annual Scientific Retreat
 Foundation
------------------------------------------------------------------------
Public Health                 $5,000.00   Building Health Equity in
 Advocates                                 Diabetes Prevention and
                                           Treatment Conference
------------------------------------------------------------------------
Raritan Valley                $3,000.00   College Campus Experience
 Community College                         Sessions for STEM High School
 Foundation                                Students
------------------------------------------------------------------------
Raritan Valley               $10,000.00   Preparing for the Next
 Community College                         Generation Science Standards--
 Foundation                                District Partnership Program
------------------------------------------------------------------------
Raritan Valley              $125,000.00   Sanofi Nursing Simulation Lab:
 Community College                         Preparing Nursing Students to
 Foundation                                Meet the Community's Health
                                           Care Needs
------------------------------------------------------------------------
Raritan Valley               $25,000.00   Galileo Scholarships:
 Community College                         Providing Access to STEM
 Foundation                                Education
------------------------------------------------------------------------
Raritan Valley               $46,100.00   Sanofi US Corporate Mentor
 Community College                         Program at RVCC
 Foundation
------------------------------------------------------------------------
Raritan Valley                $3,250.00   An Evening of Elegance for
 Community College                         Education
 Foundation
------------------------------------------------------------------------
Raritan Valley               $10,000.00   Preparing for the Next
 Community College                         Generation Science Standards
 Foundation
------------------------------------------------------------------------
Raritan Valley               $15,000.00   Galileo Scholarships:
 Community College                         Providing Access to STEM
 Foundation                                Education
------------------------------------------------------------------------
Regents University of        $10,000.00    March Kidney Fair, March 26,
 California Los                            2017
 Angeles
------------------------------------------------------------------------
Research!America             $10,000.00   National Health Research Forum
------------------------------------------------------------------------
Research!America             $25,000.00   Advocacy Awards Dinner
------------------------------------------------------------------------
RESOURCES USA INC            $10,000.00   Bastille Day 2017--Washington
                                           DC--Celebrates the Franco-
                                           American relationship
------------------------------------------------------------------------
RESOURCES USA INC.            $5,000.00   Bastille Day 2017--Boston
------------------------------------------------------------------------
Rutgers University           $20,000.00   The Sanofi US Scholarship for
 Foundation                                Veterans in the Rutgers
                                           Business School Executive
                                           Education Program
------------------------------------------------------------------------
Rutgers University            $5,000.00   Andrew Giovanni Woman in
 Foundation                                Neuroscience Endowed Travel
                                           Scholarship
------------------------------------------------------------------------
SDHB Pheo-Para                $9,900.00   SDHB Pheo-Para Coalition Gala
 Coalition, Inc.
------------------------------------------------------------------------
Seeding Labs                  $2,000.00   Positively Instrumental: 2017
                                           Instrumental Access Launch &
                                           Donor Recognition Event
------------------------------------------------------------------------
Society for                  $25,000.00   Trainee Professional
 Neuroscience                              Development Awards at
                                           Neuroscience 2017
------------------------------------------------------------------------
Society of Toxicology        $10,000.00   Society of Toxicology (SOT)
                                           Annual Meeting
------------------------------------------------------------------------
SOME INC.                     $5,000.00   2017 SOME Gala
------------------------------------------------------------------------
Somerset Alliance for         $1,000.00   NJ Smart Workplace Recognition
 the Future d.b.a                          Breakfast
 RideWise
------------------------------------------------------------------------
Somerset Health Care          $2,500.00   Healthier Somerset
 Foundation
------------------------------------------------------------------------
Springboard 2000             $25,000.00   Health Innovation Hub 2017
 Enterprises, Inc.
------------------------------------------------------------------------
State University of           $2,500.00   Wellstone Family Conference
 Iowa Foundation                           2017
------------------------------------------------------------------------
T1 Today, Inc., dba          $29,625.00   Round Table on Impact of Non-
 Children with                             Medical Switching of Insulin
 Diabetes
------------------------------------------------------------------------
T1 Today, Inc., dba          $48,500.00   Forced Non-Medical Switching
 Children with                             Awareness--November 2017
 Diabetes
------------------------------------------------------------------------
T1 Today, Inc., dba          $20,000.00   Friends for Life Orlando
 Children with                             Supporting Sponsorship
 Diabetes
------------------------------------------------------------------------
T1 Today, Inc., dba          $49,500.00   Round Table on Impact of Non-
 Children with                             Medical Switching of Insulin--
 Diabetes                                  San Diego
------------------------------------------------------------------------
Taking Control of            $25,000.00   Educating Patients and Their
 Your Diabetes                             Caregivers About The Role Of
                                           Treatments In Diabetes
                                           Management
------------------------------------------------------------------------
Taking Control of            $60,000.00   Taking Control Of Your
 Your Diabetes                             Diabetes 2017
------------------------------------------------------------------------
Taking Control of            $20,000.00   ONE: The Ultimate Conference &
 Your Diabetes                             Retreat for Adult Type 1's
------------------------------------------------------------------------
TBA Foundation               $15,000.00   Pat's Myeloma Survival School
------------------------------------------------------------------------
Teratology Society            $1,500.00   Teratology Society 57th Annual
                                           Meeting
------------------------------------------------------------------------
THE ALBERT B SABIN          $300,000.00   Arbovirus Surveillance
 VACCINE INSTITUTE                         Strengthening Phase II
 INC.
------------------------------------------------------------------------
The American Fallen           $5,700.00   2018 Portrait Donation
 Soldiers Project Inc
------------------------------------------------------------------------
The American Heart           $25,000.00   American Heart Association
 Association                               Multicultural Initiatives
------------------------------------------------------------------------
The American Heart           $50,000.00   Go Red for Women; Health
 Association                               Education Symposium
------------------------------------------------------------------------
The American Heart           $25,000.00   Heart and Stroke Ball Campaign
 Association                               2017
------------------------------------------------------------------------
The American Kidney          $50,000.00   The Hope Affair 2017--Imagine
 Fund, Inc.                                the Possibilities
------------------------------------------------------------------------
The American Kidney           $5,000.00   2017 A Pairing For Prevention
 Fund, Inc.
------------------------------------------------------------------------
The American Kidney          $20,000.00   The Hope Affair Sponsorship
 Fund, Inc.
------------------------------------------------------------------------
THE BIOBREAK                  $5,000.00   BioBreak Industry Sponsorship
 ORGANIZATION INC.
------------------------------------------------------------------------
The Broad Institute,          $2,000.00   Glom-NExT3 Symposium
 Inc.
------------------------------------------------------------------------
The Center For Great          $5,000.00   2017 Gift of Hope Gala
 Expectations Inc.
------------------------------------------------------------------------
The Children's Aid           $25,000.00   Children's Aid Keeping the
 Society                                   Promise Benefit
------------------------------------------------------------------------
The Children's                $2,000.00   2017 Conference on Clinical
 Hospital of                               Trial Readiness in the
 Philadelphia                              Leukodystrophies
------------------------------------------------------------------------
The Children's                $2,000.00   2017 Conference on Clinical
 Hospital of                               Trial Readiness in the
 Philadelphia                              Leukodystrophies
------------------------------------------------------------------------
The Children's Inn at        $10,000.00   An Evening for Hope
 NIH, Inc.
------------------------------------------------------------------------
The Council of State          $5,000.00   Bowhay Institute for
 Government, Ltd.                          Legislative Leadership
                                           Development
------------------------------------------------------------------------
The Diabetes                  $2,500.00   Giving Diabetes the Blues
 Coalition of
 Mississippi/
 Mississippi Rural
 Health Association
------------------------------------------------------------------------
The diaTribe                 $50,000.00   Consensus Conference Glycemic
 Foundation                                Outcomes Beyond A1C
------------------------------------------------------------------------
The diaTribe                 $20,000.00   11th Annual Diabetes Forum
 Foundation
------------------------------------------------------------------------
The diaTribe                 $90,000.00   Follow Up for d17: Executive
 Foundation                                Innovation Lab in Diabetes
                                           and Prediabetes
------------------------------------------------------------------------
The Economic Alliance         $2,500.00   EAM Health Purchaser Forum
 for Michigan
------------------------------------------------------------------------
The FH Foundation           $250,000.00   The CASCADE FHTM Registry
------------------------------------------------------------------------
The FH Foundation           $100,000.00   Advocates for Awareness
------------------------------------------------------------------------
The FH Foundation            $75,000.00   2017 FH Global Summit
------------------------------------------------------------------------
The Galien Foundation        $15,000.00   PRIX GALIEN USA GALIEN FORUM
------------------------------------------------------------------------
The Health                    $5,000.00   Inspire Sponsorship
 Collaborative
------------------------------------------------------------------------
THE LEUKEMIA &               $50,000.00   Blood and Marrow Stem Cell
 LYMPHOMA SOCIETY                          Transplantation Booklet and
                                           Guide
------------------------------------------------------------------------
The Medical College          $10,000.00   2017 BMT Tandem Meetings--
 of Wisconsin, Inc.                        Administrative Directors
                                           Reception
------------------------------------------------------------------------
The Mended Hearts,           $25,000.00   Patient Advocacy Network (PAN)
 Inc.                                      Training
------------------------------------------------------------------------
The Mended Hearts,           $10,000.00   National Education & Training
 Inc.                                      Conference
------------------------------------------------------------------------
The Mesothelioma              $2,000.00   Sponsorship--Clinical Trial
 Applied Research                          Awareness
 Foundation
------------------------------------------------------------------------
The New York Academy          $5,000.00   Challenge 2030: Tomorrow's
 of Science                                innovators tackle today's
                                           grand challenges
------------------------------------------------------------------------
The Ohio State               $25,000.00   Pharmacy Patient Counseling
 University                                Education
 Foundation
------------------------------------------------------------------------
The Ohio State                $1,000.00   Pharmathon 5k
 University
 Foundation
------------------------------------------------------------------------
The Partnership for           $5,000.00   PQMD London Educational Forum
 Quality Medical
 Donations
------------------------------------------------------------------------
The Pennsylvania            $150,000.00   SARP SUPPLEMENTAL FUNDING
 State University                          AGREEMENT
------------------------------------------------------------------------
THE TRANSPLANTATION           $7,500.00   The 14th Congress of the
 SOCIETY                                   International
                                           Xenotransplantation
                                           Association
------------------------------------------------------------------------
THE TRANSPLANTATION          $15,000.00   9th Congress of the
 SOCIETY                                   International Pediatric
                                           Transplant
------------------------------------------------------------------------
The Virginia Public             $700.00   Lighten Up, It's Just Politics
 Access Project
------------------------------------------------------------------------
The World Orphan Fund           $500.00   2017 Annual Wisconsin Gala
 Inc.
------------------------------------------------------------------------
Thomas Jefferson             $65,000.00   Population Health Leadership
 University                                Series (formerly Quality and
                                           Safety Leadership Series)
------------------------------------------------------------------------
Thomas Jefferson            $100,000.00   Quality and Safety Leadership
 University                                Series
------------------------------------------------------------------------
Tree Canada                  $14,089.00   Operation ReLeaf Fort McMurray
------------------------------------------------------------------------
Trustees of Boston           $65,000.00   National Association of
 University                                Community Health Workers
                                           Communications and
                                           Organizational Development
                                           Project
------------------------------------------------------------------------
Trustees of Boston            $1,000.00   Boston University's 16th
 University                                Annual CMD Symposium on
                                           Molecular Discovery: From
                                           Chemical Synthesis to
                                           Biological Applications
------------------------------------------------------------------------
Trustees of Boston           $20,000.00   iHEA's 12th World Congress in
 University                                Health Economics
------------------------------------------------------------------------
Trustees of                   $5,000.00   Translational Retinal Research
 University of                             & Therapies 2017 Symposium
 Pennsylvania
------------------------------------------------------------------------
Tufts Center for the         $30,000.00   Tufts CSDD 2017 Sponsorship
 Study of Drug
 Development c/o
 Trustees of Tufts
 College
------------------------------------------------------------------------
TULANE CANCER CENTER          $2,500.00   NOLA Bluedoo 2017
------------------------------------------------------------------------
University of Florida         $5,000.00   11th Annual Clinical Pharmacy
 Foundation                                and Pharmacology Symposium
------------------------------------------------------------------------
University of                 $5,000.00   UMN John S. Najarian Lecture &
 Minnesota Foundation                      50 Years of Pancreas
                                           Symposium
------------------------------------------------------------------------
University of New             $1,000.00   2017 Hoops4Hope Legislative
 Mexico Foundation =                       Basketball Game
 Hoops for Hope
------------------------------------------------------------------------
University of North          $20,000.00   Pharmacoepidemiology Program
 Carolina at Chapel
 Hill
------------------------------------------------------------------------
University of                $10,000.00   Unity 2017 Conference
 Southern Mississippi
 Foundation
------------------------------------------------------------------------
University of Texas          $50,000.00   Third Annual International
 Foundation-UT Austin                      Immuno-Therapy in Myeloma
                                           Scientific Workshop
------------------------------------------------------------------------
University of Utah           $50,000.00   2017 Western Atrial
                                           Fibrillation Symposium
------------------------------------------------------------------------
Us TOO International         $15,000.00   Prostate Cancer Support Group
                                           Meeting Webcast
------------------------------------------------------------------------
Us TOO International         $20,000.00   Prostate Cancer News You Can
                                           Use
------------------------------------------------------------------------
Virginia Bio                  $3,000.00   Women Building Bio--the XX
                                           Factor
------------------------------------------------------------------------
Virginia Quality              $1,000.00   VQHN Eighteenth Annual Wrap Up
 Healthcare Network                        Event
------------------------------------------------------------------------
Vision y Compromiso          $10,000.00   Vision y Compromiso's 15th
                                           Annual Conference for
                                           Promotoras and CHWs,
                                           ``Resiliency: Our Strength in
                                           Times of Change''
------------------------------------------------------------------------
Waltham West Suburban         $6,000.00   Waltham West Suburban Chamber
 Chamber of Commerce,                      of Commerce Sponsorship
 Inc.                                      Opportunities
------------------------------------------------------------------------
Washington Legal             $30,000.00   2017 General Operating Support
 Foundation
------------------------------------------------------------------------
Washington Policy             $3,500.00   2017 Annual Dinner
 Center
------------------------------------------------------------------------
Western Governors'           $10,000.00   2017-2018 Bi-annual
 Foundation                                Conferences
------------------------------------------------------------------------
Women In Government           $5,000.00   2017 Healthcare Summit--
 Foundation, Inc.                          Inspiration Station
------------------------------------------------------------------------
Women In Government          $65,000.00   2017 Healthcare Summit--
 Foundation, Inc.                          Diabetes PSAs
------------------------------------------------------------------------
WomenHeart: The              $25,000.00   2017 Wenger Awards
 National Coalition
 for Women with Heart
 Disease
------------------------------------------------------------------------
WomenHeart: The              $45,000.00   Access NOW! Key Opinion
 National Coalition                        Leaders Thought Workshop &
 for Women with Heart                      Congressional Briefing
 Disease
------------------------------------------------------------------------
Wyoming Congressional         $5,000.00   WY Congressional Award
 Award Council                             Council's Spring Awards
                                           ceremony
------------------------------------------------------------------------
ZERO--The End of              $8,000.00   Chemotherapy and Immunotherapy
 Prostate Cancer                           Sequencing in Prostate Cancer
                                           Webinar
------------------------------------------------------------------------
                        $13,245,248.00
------------------------------------------------------------------------
Product Donations          $594,228,133
 made by Sanofi US to
 the Sanofi
 Foundation for North
 Americaestimate as
 of March 2018)
------------------------------------------------------------------------


        Donations made by the Sanofi Foundation for North America
------------------------------------------------------------------------
      Legal Name         Payment Amount           Project Title
------------------------------------------------------------------------
American Cancer              $5,000.00   Hope Lodge of Framingham
 Society Inc.                             Operating Support
------------------------------------------------------------------------
American Cancer             $25,000.00   Nationwide American Cancer
 Society Inc.                             Society Hope Lodge
------------------------------------------------------------------------
American National Red       $25,000.00   2017-2018 American Red Cross
 Cross                                    Biomedical Services
------------------------------------------------------------------------
American Recreational        $3,200.00   Project Homecoming
 Military Services
------------------------------------------------------------------------
American Red Cross          $10,000.00   Disaster Relief & Home Fire
                                          Preparedness Campaign
------------------------------------------------------------------------
American Red Cross         $177,422.00   Disaster Relief--special
                                          employee match
------------------------------------------------------------------------
American Society of          $5,000.00   Daniel R. Salomon Frontiers in
 Transplantation                          Transplantation Endowment
                                          (FITE)
------------------------------------------------------------------------
Americares                  $50,000.00   Hurricane Maria Response
------------------------------------------------------------------------
Americares                 $100,000.00   Hurricane Harvey Response
------------------------------------------------------------------------
Americares                  $10,000.00   U.S. Disaster Assistance
------------------------------------------------------------------------
Camp Nejeda Foundation       $5,000.00   Camp Nejeda Campership Program
------------------------------------------------------------------------
Camp Nejeda Foundation      $10,000.00   Camp Nejeda: Helping Kids with
                                          Type 1 Diabetes Live Happier,
                                          Healthier Lives
------------------------------------------------------------------------
Camp Quality USA dba        $10,000.00   Camp Quality USA dba Camp
 Camp Quality NJ                          Quality NJ
------------------------------------------------------------------------
CANCER SUPPORT              $15,000.00   Teens Connect School Based
 COMMUNITY CENTRAL NEW                    Support Groups
 JERSEY
------------------------------------------------------------------------
Children's Health Fund      $30,000.00   Asthma Video
------------------------------------------------------------------------
Children's Health Fund     $665,000.00   Medical Home Initiative
------------------------------------------------------------------------
Children's Health Fund     $665,000.00   Medical Home Initiative
------------------------------------------------------------------------
Christ the King             $59,000.00   Christ the King Corporate Work
 Preparatory School of                    Study Program
 Newark NJ Corp.
------------------------------------------------------------------------
Christopher & Dana           $5,000.00   Reeve Patient Care & Cures--NJ
 Reeve Foundation
------------------------------------------------------------------------
Coastal Bend Food Bank       $1,000.00   Diabetes Hands On
------------------------------------------------------------------------
Deirdre O'Brien Child       $10,000.00   Advocacy Program for Child
 Advocacy Center Inc.                     Victims of Abuse and/or
                                          Neglect
------------------------------------------------------------------------
Direct Relief              $100,000.00   Hurricane Harvey Response
------------------------------------------------------------------------
Direct Relief               $50,000.00   Responding to Hurricane Maria
                                          in Puerto Rico
------------------------------------------------------------------------
Direct Relief               $10,000.00   Emergency Prep Programs
------------------------------------------------------------------------
Dress For Success            $5,000.00   General Operating Expenses
 Northern New Jersey--
 10 Counties, Inc.
------------------------------------------------------------------------
Food Bank of Somerset       $12,500.00   Back Pack Program
 County Inc.
------------------------------------------------------------------------
Heart To Heart              $25,000.00   Hurricane Relief Maria
 International Inc.
------------------------------------------------------------------------
Heart To Heart              $10,000.00   US Crisis Relief
 International Inc.
------------------------------------------------------------------------
Heart To Heart              $25,000.00   Hurricane Harvey Response
 International Inc.
------------------------------------------------------------------------
Hyacinth Foundation A       $10,000.00   General Support-Sanofi in Our
 New Jersey Nonprofit                     Communities, Celebrating
 Corporation                              Diversity
------------------------------------------------------------------------
Hyacinth Foundation A       $10,000.00   General Support
 New Jersey Nonprofit
 Corporation
------------------------------------------------------------------------
International Myeloma       $18,950.00   International Myeloma
 Foundation                               Foundation Mission Support
------------------------------------------------------------------------
Jersey Battered              $5,000.00   General Operating
 Women's Service, Inc.
------------------------------------------------------------------------
Kids Corporation II         $10,000.00   Kids Corp General Operating
------------------------------------------------------------------------
Map International           $10,000.00   MAP's Domestic Medicine Program
------------------------------------------------------------------------
March of Dimes              $86,000.00   Supporting NICU Babies and
 Foundation                               Family's
------------------------------------------------------------------------
Matheny School and           $5,000.00   Matheny Center for Medicine and
 Hospital Inc.                            Dentistry
------------------------------------------------------------------------
Matheny School and           $5,000.00   Matheny School STEM Program
 Hospital Inc.
------------------------------------------------------------------------
Midland Adult Services       $5,000.00   Midland Helping Hands & Midland
 Inc.                                     Meals on Wheels Employment
                                          Training Programs
------------------------------------------------------------------------
Multiple Myeloma            $18,950.00   Mambo for Myeloma
 Research Foundation
------------------------------------------------------------------------
NJ SEEDS                    $10,000.00   Young Scholars Program--Health
                                          Sessions
------------------------------------------------------------------------
NJ Sharing Network           $5,000.00   Multicultural Outreach
 Foundation                               Initiative
------------------------------------------------------------------------
Partners in Research        $25,000.00   Sanofi Biogenius Canada
 Canada
------------------------------------------------------------------------
PATIENT EMPOWERMENT         $25,000.00   ASCO, AUA Coverage for Advanced
 NETWORK                                  Prostate Cancer Patients
------------------------------------------------------------------------
Rise Against Hunger          $7,500.00   Rise Against Hunger Disaster
                                          Ready Response Program
------------------------------------------------------------------------
Rutgers University          $10,000.00   Vets4Warriors
 Foundation
------------------------------------------------------------------------
Safe + Sound Somerset       $10,000.00   Residential Children's Program
------------------------------------------------------------------------
Sheltered Yoga               $5,000.00   Sheltered Yoga NJ Programming
------------------------------------------------------------------------
Somerset County YMCA         $6,000.00   Somerville YMCA/Annual Campaign
------------------------------------------------------------------------
Somerset Health Care         $5,000.00   Quality CPR Saves Lives
 Foundation
------------------------------------------------------------------------
Somerset Health Care        $10,000.00   El poder
 Foundation
------------------------------------------------------------------------
Somerset Health Care        $10,000.00   El poder
 Foundation
------------------------------------------------------------------------
Somerset Health Care        $18,560.00   1st Healthcare Conference for
 Foundation                               the LGBT Community
------------------------------------------------------------------------
Somerset Health Care         $5,000.00   Quality CPR Saves Lives
 Foundation
------------------------------------------------------------------------
The Center For Great        $10,000.00   Adult Women & their Children
 Expectations Inc.
------------------------------------------------------------------------
The Center For Great        $10,000.00   Adult Women & their Children
 Expectations Inc.
------------------------------------------------------------------------
The Children's Inn at      $500,000.00   Sanofi US Legacy Endowment Fund
 NIH, Inc.                                at The Children's Inn at NIH
                                          Sanofi US Legacy Endowment
                                          Fund at The Children's Inn at
                                          NIH
------------------------------------------------------------------------
The Children's Inn at      $500,000.00   Sanofi US Legacy Endowment Fund
 NIH, Inc.                                at The Children's Inn at NIH
------------------------------------------------------------------------
The Children's Inn at      $500,000.00   Sanofi US Legacy Endowment Fund
 NIH, Inc.                                at The Children's Inn at NIH
------------------------------------------------------------------------
THE LEUKEMIA &              $18,950.00   Fiscal Year 2017 Myeloma
 LYMPHOMA SOCIETY                         Patient Education
------------------------------------------------------------------------
The Partnership for          $5,000.00   General Support for PQMD
 Quality Medical
 Donations
------------------------------------------------------------------------
The Salvation Army          $10,000.00   Healthy Food Pantry Program
------------------------------------------------------------------------
Trustees of University      $20,000.00   Research Training in
 of Pennsylvania                          Pharmacoepidemiology
------------------------------------------------------------------------
Tyler Clementi               $5,000.00   New Jersey Programs
 Foundation Inc
------------------------------------------------------------------------
United Way of Monroe        $59,069.70   SP 2017 UW Campaign Match
 County
------------------------------------------------------------------------
United Way of Northern      $75,000.00   Caregivers Coalition
 New Jersey
------------------------------------------------------------------------
Visiting Nurse              $10,000.00   General Operating
 Association of
 Somerset Hills
------------------------------------------------------------------------
                         $3,682,101.70
------------------------------------------------------------------------
    Grand Total            $16,927,350
------------------------------------------------------------------------


                 Sponsorships and Charitable Donations
                       1st Jan 2015-31st Dec 2015
    Sanofi US and its affiliate Genzyme Corporation are committed to
   supporting sponsorships for specific activities and initiatives of
    healthcare organizations and institutions, independent medical or
professional societies, trade organizations and organized patient groups
  to improve patient care and provide information to the medical and/or
  patient communities. The goal of our charitable giving approach is to
 fund general operational support for patient/disease organizations, or
program support for community-based organizations. Sanofi US and Genzyme
    Corporation are part of the Sanofi Group, a global pharmaceutical
                                company.
 Applicant names are provided by the requestor. If applicants apply as a
  group for a single activity; all applicants may be not be identified
 above. ``Funding Amount'' is the amount that the Company funded during
  2015 identified above. ``Funding Amount'' does not include funds that
   may have been provided by other affiliated Sanofi Company Entities
                         (e.g., Sanofi Pasteur).
 
   Recipient Name(s)             Activity Title          Funding Amount
 
Acacia In Kenya          Volunteer Match                       $1,000.00
 
Acacia In Kenya          Volunteer Match                       $1,000.00
 
Accelerated Cure         MS Discovery: The Podcast of        $102,400.00
 Project                  the MS Discovery Forum
 
Accelerated Cure         Data Visualizations in               $89,400.00
 Project                  Multiple Sclerosis
 
Acid Maltase Deficiency  AMDA Patient Education               $35,000.00
 Association Inc.         Programs
 
Acid Maltase Deficiency  The 2015 AMDA/IPA                    $20,000.00
 Association Inc.         International Pompe Patient
                          and Scientific Conference
 
Acid Maltase Deficiency  AMDA Patient Education               $12,000.00
 Association Inc.         Programs
 
Acid Maltase Deficiency  Pull for Pompe Event                  $3,000.00
 Association Inc.
 
ALD Connect Inc.         ALD Connect Meeting                   $4,000.00
 
Alport Syndrome          2015 International Workshop           $2,500.00
 Foundation, Inc.         on Alport Syndrome
 
American Academy of      2015 Palatucci Advocacy              $50,000.00
 Neurology Institute      Leadership Forum
 
American Academy of      Fellows Scholarship Program          $20,000.00
 Neurology Institute
 
American Academy of      Residents Scholarship Program        $20,000.00
 Neurology Institute
 
American Academy of      2014-2015 Emerging Leaders           $17,500.00
 Neurology Institute      Forum
 
American Academy of      Brain Health Fair                    $10,000.00
 Neurology Institute
 
American Association of  2015 Pan-American Scientific         $50,000.00
 Clinical                 Symposia on Clinical
 Endocrinologists         Endocrinology in Latin
                          America
 
American Autoimmune and  50 Cents for 50 Million               $5,000.00
 Related Diseases         Campaign AND Fight For
 Association              Immunity Comedy Show
 
American Chemical        ACS BIOT 2015 Annual Meeting          $5,000.00
 Society Merck And Co
 Inc.
 
American College of      Summer Genetics Scholars             $75,000.00
 Medical Genetics         Program
 Foundation
 
American Physiological   Experimental Biology 2015             $3,000.00
 Society
 
American Red Cross of    Women Who Care, A Leadership          $5,000.00
 Massachusetts            Breakfast
 
American Society of      ASGCT 18th Annual Meeting             $5,000.00
 Gene Therapy
 
American Society of      ASN Kidney Week 2015                 $30,000.00
 Nephrology               Exhibitor Spotlight
 
Andrew's Buddies         FightSMA Annual Research              $3,000.00
 Corporation dba          Conference 2015
 FightSMA
 
ANERA (American Near     ANERA (American Near East             $5,000.00
 East Refugee Aid)        Refugee Aid) Annual Dinner
 
Ann & Robert H. Lurie    MPS Patient and Family                $2,000.00
 Children's Hospital of   Conference
 Chicago
 
Arizona Kidney           16th Annual Southwest                 $6,000.00
 Foundation               Nephrology Conference
 
Ashland Fire Department  Community Support for Ashland        $40,000.00
 Association              Fire Department Association
 
Assistance Fund Inc.     Multiple Sclerosis Disease        $5,300,000.00
                          Patient Assistance Fund
                          Program
 
Assistance Fund Inc.     Multiple Sclerosis Disease          $500,000.00
                          Patient Assistance Fund
                          Program
 
Association For          Annual Conference; Family             $6,000.00
 Glycogen Storage         Assistance; The Ray
 Disease
 
Beauty Bus Foundation    6th Annual Beauty Drive for           $3,000.00
                          Patients and Caregivers
 
Berkshire Resource       2015 Annual Gala                      $5,000.00
 Project, Inc.
 
Big Brothers Big         Big Brothers Big Sisters             $10,000.00
 Sisters of Central       Central Mass/Metrowest
 Mass Metrowest Inc.      (BBBSCM) STEM Institute
 
Biomedical Science       Evening of Hope: To support          $75,000.00
 Careers Program          underrepresented minority
                          students/fellows interested
                          in science
 
Biomedical Science       Hope Scholarship 2015-2016            $7,500.00
 Careers Program
 
Boston Health Care For   Life Essentials Community            $25,000.00
 The Homeless Program     Support Program
 Inc.
 
Boston Plan For          Boston Teacher Residency: A          $15,000.00
 Excellence in the        High-Quality Pipeline for
 Public Schools           Boston Public Schools' STEM
 Foundation               Teachers
 
Boston Private Industry  2015 Corporate Contribution's        $15,000.00
 Council                  Campaign
 
Boston Private Industry  Volunteer Match                       $1,000.00
 Council
 
Bottom Line              Boston STEM Success Program          $15,000.00
 
Boys and Girls Clubs of  Staffing & Transportation for        $25,000.00
 MetroWest                Increased Membership at
                          BGCMW's Framingham Clubhouse
 
Boys and Girls Clubs of  2015 Bids for Kids Auction &         $10,000.00
 MetroWest                Gala
 
Boys and Girls Clubs of  Volunteer Match                       $4,000.00
 MetroWest
 
Boys and Girls Clubs of  The 2015 Great Pumpkin Glow           $5,000.00
 Middlesex County Inc.
 
Breakthrough Greater     Full STEAM (Science                  $10,000.00
 Boston                   Technology, Engineering,
                          Arts, and Math) Ahead
                          Program
 
Cambridge Family &       2015 Circle of Friends Gala &         $5,000.00
 Children's Service       Auction
 
Cambridge School         Volunteer Match                       $1,000.00
 Volunteers, Inc.
 
Camp Korey               Metabolic Disorders Family            $5,000.00
                          Weekend
 
Can Do Multiple          2015 TAKE CHARGE Program             $55,000.00
 Sclerosis
 
Can Do Multiple          Can Do Program                       $50,000.00
 Sclerosis
 
Can Do Multiple          2015 JUMPSTART Program               $50,000.00
 Sclerosis
 
Can Do Multiple          Can Do 2015 Online                   $40,000.00
 Sclerosis                Programming
 
Can Do Multiple          Vertical Express for Can Do          $25,000.00
 Sclerosis                MS Events
 
Canavan Foundation       Jewish Genetic Disease                $4,500.00
                          Leadership Database
                          Expansion Project
 
Case Management Society  CMSA 25th Annual Conference &        $14,000.00
 of America               Expo
 
Case Management Society  CMSA 25th Annual Conference &         $4,800.00
 of America               Expo (Booth)
 
Case Management Society  Case Management Society of            $1,000.00
 of New England           New England's 26th Annual
                          Conference and Exhibitor
                          Expo
 
CASSS--An International  CMC Strategy Forums                   $2,500.00
 Separation Science
 Society
 
Charcot-Marie-Tooth      CMTA's Boston Patient/Family          $5,000.00
 Association              Conference
 
Charcot-Marie-Tooth      CMTA's Boston Patient/Family          $2,000.00
 Association              Conference
 
Children's Hospital      Global Pediatric Innovation          $20,000.00
 Boston                   Summit + Awards 2015
 
Children's Hospital      La Gala de Milagros para              $5,000.00
 Corporation              Ninos
 
Church Hillers Inc.      Volunteer Match                       $1,000.00
 
City Sprouts, Inc.       After School Ecology Clubs            $7,000.00
 
Colon Cancer Coalition   Volunteer Match                       $2,000.00
 
Community Boating, Inc.  Universal Access Program             $15,000.00
                          2015--Patient Assistance
                          Program
 
Community Farms          Fresh Food Access Program            $12,000.00
 Outreach
 
Community Rowing, Inc.   Let's Row Boston                     $15,000.00
 
Community Servings,      Pie in the Sky                       $10,000.00
 Inc.
 
Consortium of Multiple   29th Annual Meeting of the           $52,000.00
 Sclerosis Centers        Consortium of Multiple
                          Sclerosis Centers Breakfast
 
Council on Renal         Patient Empowerment Workshop          $1,000.00
 Nutrition of Western
 PA
 
Courage to Make a        Courage: Living life without          $1,000.00
 Difference Inc.          limit patient videos
 
Cradles to Crayons Inc.  Ready for School and Backpack-       $20,000.00
                          a-Thon
 
Cystic Fibrosis          Uncork the Cure Event                $10,000.00
 Foundation
 
DEAF, Inc.--             Deaf-Accessible Medical Case         $10,000.00
 Developmental            Management and Health
 Evaluation and           Education
 Adjustment Facilities,
 Inc.
 
Deliver The Dream Inc.   Community Champions Awards            $2,500.00
 
Department of Neurology  Shop to Stop Multiple                $10,000.00
 Multiple Sclerosis       Sclerosis
 Center of Excellence
 
Dimock Community Health  Building the Road to                $150,000.00
 Center                   Recovery--Expanding and
                          Renovating Acute Treatment
                          Services
 
DISARM Education FUND,   Combating Rare Diseases and          $20,000.00
 INC.                     Raising Awareness in the
                          Developing World
 
East End House Inc.      Generating and Evaluating New        $20,000.00
                          Adventures in Science After
                          School (GENASAS)
 
East End House Inc.      Volunteer Match                       $2,000.00
 
Emory Genetics           LSDC Patient Meetings                $27,390.00
 Laboratory
 
Engineering Conferences  Integrated Continuous                $10,000.00
 International            Biomanufacturing II
                          Conference
 
EveryLife Foundation     Rare Voice Awards Gala               $20,000.00
 for Rare Diseases
 
EveryLife Foundation     EveryLife Foundation Annual          $10,000.00
 for Rare Diseases        Rare Disease Scientific
                          Workshop: Patient Engagement
                          in the Clinical Development
                          Process
 
Fabry Support &          FSIG Expert Fabry Conference         $50,000.00
 Information Group        2015
 
Fabry Support &          FSIG Patient Assistance Fund         $40,000.00
 Information Group
 
Fabry Support &          FSIG Patient Assistance Fund         $40,000.00
 Information Group
 
Fabry Support &          Rapid Assistance Funds--             $30,000.00
 Information Group        Patient Assistance Program
 
Fabry Support &          FSIG Newsletter                      $12,000.00
 Information Group
 
Fabry Support &          2015 FSIG Fabry Fun Run/Walk          $1,500.00
 Information Group        & FSIG Fabry Get Together
                          Meeting
 
Family Promise           Keep the Promise: An evening          $2,500.00
 Metrowest Inc.           of food tasting to benefit
                          families that are homeless
 
Foundation of the        2016 CMSC Annual Meeting--          $414,000.00
 Consortium of Multiple   Celebrating 30 Years of MS
 Sclerosis Centers        Care
 
Foundation of the        FCMSC 2015-2016 Pilot                $44,000.00
 Consortium of Multiple   Research Grant Award in
 Sclerosis Centers        Multiple Sclerosis
 
Foundation of the        NARCOMS Now Patient Quarterly        $33,358.00
 Consortium of Multiple   Magazine
 Sclerosis Centers
 
Foundation of the        2015-2016 FCMSC Medical              $22,000.00
 Consortium of Multiple   Resident Annual Meeting
 Sclerosis Centers        Scientific Scholarships
 
Foundation of the        2015-2016 Workforce of the           $22,000.00
 Consortium of Multiple   Future: Medical Student
 Sclerosis Centers        Scholarships
 
Framingham Townwide PTO  Volunteer Match                       $1,000.00
 Council
 
Franciscan Children's    Adaptive Sports Program for          $10,000.00
 Hospital and             Children with Disabilities
 Rehabilitation Center
 
Friends of Hopkinton     Community Support for general         $4,000.00
 SPEAC                    operating
 
Friends of Resiliency    Academic Support component of        $10,000.00
 for Life Inc.            Resiliency for Life (RFL)
 
Friends of Resiliency    Volunteer Match                       $1,000.00
 for Life Inc.
 
Friends of the           Community Support for Friends        $16,000.00
 Hopkinton Seniors        group to raise funds for
                          nutrition programs
 
FSH Society, Inc.        FSH Society                           $2,000.00
                          Facioscapulohumeral Muscular
                          Dystrophy [FSHD] 2015
                          International Research
                          Consortium & Research
                          Planning Meetings
 
Fundacion de Esclerosis  MS Community Educational             $20,000.00
 Multiple de Puerto       Conferences
 Rico
 
Fundacion de Esclerosis  Abrazarte a la vida Patient           $2,500.00
 Multiple de Puerto       Fundraising Event
 Rico
 
Gateway Area Chapter     Community Walk MS 2015                $5,000.00
 
Gateway Area Chapter     Women on the Move Luncheon            $2,500.00
                          2015
 
Generation Citizen Inc.  Generation Citizen Spring             $5,000.00
                          2015 Civics Day
 
Georgia Chapter of the   Non-AAP industry/foundation           $3,500.00
 American Academy of      symposium
 Pediatrics
 
Girl Scouts of Eastern   Girls Building Self-esteem           $10,000.00
 Massachusetts Inc.
 
Global Genes             4th Annual RARE Tribute to           $25,000.00
                          Champions Event
 
Global Genes             Global Genes RARE Patient            $25,000.00
                          Advocacy Summit
 
Global Genes             Global Genes Corporate               $15,000.00
                          Alliance Program
 
Global Genes             Give RARE Disease Giving Day         $10,000.00
 
Global Genes             Pixar's The Good Dinosaur--          $10,000.00
                          Exclusive Screening &
                          Fundraiser
 
Global Genes             Tribute to Champions--                $7,460.00
                          Expression of Hope Art
                          Exhibit
 
Global Genes             RARE Toolkit & Educational            $5,000.00
                          Podcast Programs
 
Gordon Research          Lysosomal Diseases Gordon             $5,000.00
 Conferences              Research Conference and
                          Gordon Research Seminar
 
Gordon Research          2015 CAG Repeat Disorders             $2,000.00
 Conferences              Gordon Research Conference
 
Greater Boston Chamber   Chamber's 2015 Annual Meeting        $10,000.00
 of Commerce
 
Habitat For Humanity     Holliston Build Project              $15,000.00
 Metrowest--Greater
 Worcester Inc.
 
Habitat For Humanity     Volunteer Match                       $2,000.00
 Metrowest--Greater
 Worcester Inc.
 
Health Care For All      Ethnic Media and Grassroots          $10,000.00
 Inc.                     Outreach to Improve Health
                          Coverage Access in
                          Framingham
 
Health Technology        HTAI Annual Meeting 2015             $20,000.00
 Assessment
 International
 
Hearts & Noses Hospital  Ongoing Hospital Clown Visits        $15,000.00
 Clown Troupe Inc.        to Ill and Disabled Children
                          in Greater Boston
 
Holy Name Health Care    18th Annual Spring Fashion           $15,000.00
 Foundation Inc.          Fling for MS
 
Horizons for Homeless    17th Annual Women's Breakfast         $3,500.00
 Children
 
Huntington Study Group   HSG 2015: Building Our Future         $1,500.00
 Ltd.
 
Huntington's Disease     Huntington's Disease Society          $2,500.00
 Society of America       of America 30th Annual
                          Convention
 
Icahn School of          13th Annual Gala in Support          $25,000.00
 Medicine at Mount        of the Corinne Goldsmith
 Sinai                    Dickinson Center for
                          Multiple Sclerosis at Mount
                          Sinai
 
Icahn School of          13th Annual Gala in Support          $12,000.00
 Medicine at Mount        of the Corinne Goldsmith
 Sinai                    Dickinson Center for
                          Multiple Sclerosis at Mount
                          Sinai
 
International            2015 MS Perspectives                 $75,000.00
 Organization of          Publication
 Multiple Sclerosis
 Nurses
 
International            2015 Annual Meeting IOMSN            $30,000.00
 Organization of          Dinner
 Multiple Sclerosis
 Nurses
 
International Society    Glycoproteinoses: Fourth              $5,000.00
 For Mannosidosis &       International Conference on
 Related Disease Inc.     Advances in Pathogenesis and
                          Therapy
 
International Society    31st International Conference         $2,000.00
 For                      on Pharmacoepidemiology
 Pharmacoepidemiology
 
International Society    ISN Forefronts                        $3,500.00
 of Nephrology            ``Immunomodulation of Cardio-
                          Renal Function--A focus on
                          cardio-renal pathophysiology
                          and immunity'' (Oct 22-25,
                          2015, Shenzhen, China)
 
Italian Home For         City Lights Gala                      $5,000.00
 Children Inc.
 
Japan Society of Boston  2015 Japan Society of Boston          $5,000.00
                          Annual Dinner
 
Jewish Federation of     Expanding Footprint of Jewish        $10,000.00
 southern New Jersey      Genetic Disease Awareness in
                          South Jersey
 
Jewish Genetic Disease   Jewish Genetic Disease                $5,000.00
 Consortium (JGDC)        Consortium Screening
                          Awareness Program
 
Jewish Genetic Diseases  PHOENIX--Our Heritage and our           $980.00
 Center of Greater        Health--Ashkenazi Jewish
 Phoenix                  Genetics Disease and the
                          Founder Effect
 
Jewish Genetic Diseases  TUCSON--Our Heritage and our            $950.00
 Center of Greater        Health--Ashkenazi Jewish
 Phoenix                  Genetic Disease and the
                          Founder Effect
 
Joseph M. Smith          JMSCHS's Prenatal Program            $15,000.00
 Community Health
 Center, Inc.
 
Kidney Foundation of     24th Annual Wine Affair Event         $1,000.00
 Northwest Ohio           for Disease Awareness
 
Kidney Foundation of     Kilometers for Kidneys                  $500.00
 Northwest Ohio
 
Light of Life            Light of Life Foundation 2015        $25,000.00
 Foundation               Patient Support Activities
 
Light of Life            Light of Life Foundation             $20,000.00
 Foundation               Patient Awareness Program
 
Light of Life            Light of Life Foundation              $1,000.00
 Foundation               Night of Comedy Fundraiser
 
Little Brothers/Friends  Medical Escort/Transport and          $7,500.00
 of the Elderly           Prescription Escort Patient
                          Assistance Program
 
Little Miss Hannah       Little Miss Hannah Foundation         $8,000.00
 Foundation               General Operating Support
 
Little Miss Hannah       Little Miss Hannah's Rainbows         $1,000.00
 Foundation               in the Wind Festival
 
Lysosomal and Rare       Towards a patient-centered           $10,000.00
 Disorders Research and   disease registry; Connecting
 Treatment Center Inc.    the patches for Gaucher
                          Disease
 
March of Dimes           March for Babies                     $15,000.00
 
March of Dimes           Black Ties for Babies Gala           $10,000.00
 
March of Dimes           Volunteer Match                       $2,000.00
 
March of Dimes           Volunteer Match                       $1,000.00
 
March of Dimes           Volunteer Match                       $1,000.00
 
Margaret Fuller          Scholarships for Port/Area IV        $15,000.00
 Neighborhood House       Youth to Attend Summer Camp
                          at Margaret Fuller House
 
Mass Insight Education   College Success Program              $15,000.00
 and Research Institute
 Inc.
 
Massachusetts Bay        STEM Mentor Program                  $26,500.00
 Community College
 Foundation
 
Massachusetts            Patient Advocacy Summit--Live        $10,000.00
 Biotechnology Council    & Breathe: Building a
                          Patient Centered Biotech
 
Massachusetts            BioTeach Life Sciences               $50,000.00
 Biotechnology            Student Program
 Education Foundation
 Inc.
 
Massachusetts Institute  Cambridge Science Festival            $5,000.00
 of Technology
 
Massachusetts Outdoor    DFW Plymouth Red-bellied              $5,000.00
 Heritage Foundation      Cooter Head-starting Program
 Inc.
 
Massachusetts Outdoor    Volunteer Match                       $1,000.00
 Heritage Foundation
 Inc.
 
Massachusetts State      Massachusetts State Science &        $50,000.00
 Science and              Engineering Fair
 Engineering Fair, Inc.
 
Mercy Foundation         Mercy Multiple Sclerosis (MS)        $20,000.00
                          Achievement Center Wellness
                          Programs
 
Metrowest Free Medical   Chronic Disease Patient              $10,000.00
 Program Inc.             Assistance Program
 
Mid America MS           The Race to Nowhere 2015              $5,000.00
 Achievement Center
 
Mid America MS           The Race to Nowhere 2015              $2,500.00
 Achievement Center
 
Mid America MS           Eat Bid Laugh Event                   $2,500.00
 Achievement Center       benefiting the Mid-America
                          Multiple Sclerosis
                          Achievement Center (MSAC) in
                          Kansas City
 
Milwaukee Synagogue for  Gaucher Disease Education             $5,000.00
 Russian Jews             Program
 
MLD Foundation           RUSP Roundtable                       $4,000.00
 
MS Cure Fund             Women Thriving With MS              $125,000.00
 
MS Cure Fund             Risks & Benefits Program            $103,700.00
 
MS Cure Fund             Resource Information Database        $12,360.00
                          Conversion and Website
                          Integration
 
MS Cure Fund             MS Cure Newsletter                   $10,000.00
 
MS Cure Fund             Lifestyle Management Programs         $8,250.00
                          Fall 2015
 
MS Hope for a Cure Inc.  2015 MS Cycle for a Cure--A           $5,000.00
                          Ride for Research (6 event
                          sites)
 
MS Views and News Inc.   2015--MS Symposium SERIES--          $64,491.00
                          ``The Neurological Aspects
                          of MS''
 
MS Views and News Inc.   Empowering MS Communities in         $46,000.00
                          America's Heartland series--
                          2
 
MS Views and News Inc.   BRING IT ON!--``Everything           $27,835.00
                          You Want to Know about MS''
                          a Q&A program
 
MS Views and News Inc.   Empowering MS Communities in         $22,000.00
                          America's Hearthland series
 
MS Views and News Inc.   Women's Health Issues with           $16,924.75
                          Multiple Sclerosis
 
MS Views and News Inc.   New and Emerging Therapies           $15,925.00
                          plus Invisible Symptoms of
                          MS
 
MS Views and News Inc.   New and Emerging Treatment           $14,750.00
                          Options plus Invisible
                          Symptoms of MS--Chicago
 
MS Views and News Inc.   BRING IT ON!--Everything you         $12,295.00
                          want to Know about MS--Q&A
 
MS Views and News Inc.   Women's Health with Multiple          $9,582.00
                          Sclerosis
 
MS Views and News Inc.   Men's Health Issues with              $9,178.50
                          Multiple Sclerosis
 
MS Views and News Inc.   2015 Renewal of Annual                $7,900.00
                          Display Sponsorship
 
MS Views and News Inc.   MS Views and News--5th Annual         $3,000.00
                          Bowlathon Fundraiser to
                          Benefit MS Education and
                          Stem Cell Research
 
MSWorld, Inc.            2015 MSWorld Conference              $20,000.00
                          Coverage
 
MSWorld, Inc.            2015 MSWorld ``Wellness              $20,000.00
                          Unleashed Program''
 
Multiple Sclerosis       Crossfire: The Science and          $436,320.00
 Association of America   Emotion of Risk
 
Multiple Sclerosis       MSAA MRI Patient Assistance         $350,000.00
 Association of America   Fund
 
Multiple Sclerosis       Hot Topics in Multiple              $217,941.00
 Association of America   Sclerosis: An Interactive
                          Series of MS Patient
                          Education Programs
 
Multiple Sclerosis       Swim for MS In Person Program        $58,985.00
 Association of America   Pilot Series
 
Multiple Sclerosis       MSAA's 2015 Improving Lives          $15,000.00
 Association of America   Benefit
 
Multiple Sclerosis       MS Festival Program                  $10,000.00
 Center of Georgia
 
Multiple Sclerosis       Health, Hope & Hops Program           $7,000.00
 Center of Georgia
 
Multiple Sclerosis       Foundation's Assistive               $50,000.00
 Foundation               Technology Program
 
Multiple Sclerosis       Support Group News quarterly         $27,300.00
 Foundation               informational newsletter
 
Multiple Sclerosis       African Americans with MS--          $20,000.00
 Foundation               The Medical, Cultural and
                          Psychological Differences
 
Multiple Sclerosis       Resource Website                    $117,367.00
 International            Communications Support
 Federation Foundation
 Inc.
 
Multiple Sclerosis       Middle East Patient Awareness        $78,245.00
 International            Program
 Federation Foundation
 Inc.
 
Multiple Sclerosis       Arab Region Patient Awareness        $60,117.00
 International            Program
 Federation Foundation
 Inc.
 
Multiple Sclerosis       World MS Day 2015 Campaign           $46,947.00
 International
 Federation Foundation
 Inc.
 
Multiple Sclerosis       Latin America Resource               $41,950.00
 International            Analysis Project
 Federation Foundation
 Inc.
 
Multiple Sclerosis       Global Patient Awareness             $39,122.00
 International            Program
 Federation Foundation
 Inc.
 
Multiple Sclerosis       MSQLP's 9th Annual Walk 'n            $1,500.00
 Quality of Life          Roll Fundraiser
 Project Corporation
 
Multiple Sclerosis       2015 Mission Steps Wak & MS           $8,000.00
 Resources of Central     Awareness Day
 New York, Inc.
 
Muscular Dystrophy       Muscle Walk 2015                      $1,000.00
 Association--Lake
 Mary, FL
 
Muscular Dystrophy       2015 MDA Muscle Summit                $8,000.00
 Association--Alameda,
 CA
 
Muscular Dystrophy       MDA Newsletter                        $2,000.00
 Association--Albany,
 NY
 
Muscular Dystrophy       2015 MDA Research Seminar             $2,000.00
 Association--Albany,
 NY
 
Muscular Dystrophy       New Mexico MDA Muscle Walk            $1,000.00
 Association--Albuquerq
 ue, NM
 
Muscular Dystrophy       2015 MDA Muscle Summit                $8,000.00
 Association--Allentown
 , PA
 
Muscular Dystrophy       Muscle Walk Greater Lehigh            $1,000.00
 Association--Allentown   Valley
 , PA
 
Muscular Dystrophy       17th Annual Black and Blue            $5,000.00
 Association--Ark         Ball
 Valley, Richmond, VA
 
Muscular Dystrophy       Muscle Walk Greater Fort              $1,000.00
 Association--Ark         Wayne
 Valley, Richmond, VA
 
Muscular Dystrophy       Muscle Walk Ft Myers, FL              $1,000.00
 Association--Ark
 Valley, Richmond, VA
 
Muscular Dystrophy       Muscle Walk Pittsburgh                $1,000.00
 Association--Ark
 Valley, Richmond, VA
 
Muscular Dystrophy       Muscle Walk Springfield, MO           $1,000.00
 Association--Ark
 Valley, Richmond, VA
 
Muscular Dystrophy       Muscle Walk Richmond, VA              $1,000.00
 Association--Ark
 Valley, Richmond, VA
 
Muscular Dystrophy       Muscle Walk Central Texas             $1,000.00
 Association--Austin,
 TX
 
Muscular Dystrophy       2015 Muscular Dystrophy               $1,000.00
 Association--Billings,   Summer Camp of Montana
 MT
 
Muscular Dystrophy       Muscle Walk Montana                   $1,000.00
 Association--Billings,
 MT
 
Muscular Dystrophy       MDA Health Patient Care               $1,000.00
 Association -            Services Program
 Birmingham, AL
 
Muscular Dystrophy       MDA Idaho Summer Camp                 $1,000.00
 Association--Boise, ID
 
Muscular Dystrophy       MDA Superhero Muscle Walk and         $1,000.00
 Association--Boise, ID   5k Fun Run
 
Muscular Dystrophy       Muscle Walk of Chattanooga            $2,500.00
 Association--Brentwood
 , TN
 
Muscular Dystrophy       Muscle Walk of Nashville              $1,000.00
 Association--Brentwood
 , TN
 
Muscular Dystrophy       2015 Nashville Muscle Team            $1,000.00
 Association--Brentwood   Gala
 , TN
 
Muscular Dystrophy       Muscle Walk of Nashville              $1,000.00
 Association--Brentwood
 , TN
 
Muscular Dystrophy       Muscle Walk of Greater                $1,000.00
 Association--Brookfiel   Milwaukee
 d, WI
 
Muscular Dystrophy       Muscle Walk of Greater                $1,000.00
 Association--Brookfiel   Madison
 d, WI
 
Muscular Dystrophy       Muscle Walk 2015                      $1,000.00
 Association--Broomall,
 PA
 
Muscular Dystrophy       Muscle Walk Quad Cities               $1,000.00
 Association--Cedar
 Rapids, IA
 
Muscular Dystrophy       Muscle Walk Des Moines                $1,000.00
 Association--Cedar
 Rapids, IA
 
Muscular Dystrophy       Muscle Walk Iowa City                 $1,000.00
 Association--Cedar
 Rapids, IA
 
Muscular Dystrophy       Muscle Walk Iowa City                 $1,000.00
 Association--Cedar
 Rapids, IA
 
Muscular Dystrophy       Muscle Walk Waterloo                  $1,000.00
 Association--Cedar
 Rapids, IA
 
Muscular Dystrophy       Muscle Walk Des Moines                $1,000.00
 Association--Cedar
 Rapids, IA
 
Muscular Dystrophy       Mucscle Walk Morgantown               $1,000.00
 Association--Charlesto
 n, WV
 
Muscular Dystrophy       Muscle Walk 2015                      $1,000.00
 Association--Charlotte
 , NC
 
Muscular Dystrophy       MDA--LGMD Genetic Testing           $700,000.00
 Association--Chicago,    Program
 IL
 
Muscular Dystrophy       MDA Pompe Testing Program            $60,000.00
 Association--Chicago,
 IL
 
Muscular Dystrophy       2015 Muscle Summit                    $8,000.00
 Association--Chicago,
 IL
 
Muscular Dystrophy       MDA Illinois Muscle Summit            $8,000.00
 Association--Chicago,
 IL
 
Muscular Dystrophy       Muscular Dystrophy                    $2,000.00
 Association--Chicago,    Association, Third Quarter
 IL                       Newsletter
 
Muscular Dystrophy       Muscle Walk 2015                      $1,000.00
 Association--Chicago,
 IL
 
Muscular Dystrophy       MDA-ALS Muscle Walk                   $1,000.00
 Association--Chicago,
 IL
 
Muscular Dystrophy       2015 Southern Ohio Muscular           $1,000.00
 Association--Cincinnat   Dystrophy Association Summer
 i, OH                    Camp
 
Muscular Dystrophy       Muscle Walk of Greater                $1,000.00
 Association--Cincinnat   Cincinnati
 i, OH
 
Muscular Dystrophy       Muscle Walk of Greater                $1,000.00
 Association--Cleveland   Cleveland
 , OH
 
Muscular Dystrophy       MDA Winter Newsletter                 $2,500.00
 Association--Columbia,
 SC
 
Muscular Dystrophy       Road Map to Independence for          $2,000.00
 Association--Columbia,   Young Adults Resource
 SC                       Program
 
Muscular Dystrophy       MDA Fall Newsletter                   $2,000.00
 Association--Columbia,
 SC
 
Muscular Dystrophy       Muscle Walk                           $1,000.00
 Association--Columbia,
 SC
 
Muscular Dystrophy       Muscle Walk of Denver                 $1,000.00
 Association--Denver,
 CO
 
Muscular Dystrophy       Muscle Walk of Chicagoland &          $2,000.00
 Association--Downers     Muscle Walk of Rockford
 Grove, IL
 
Muscular Dystrophy       Muscle Walk 2015                      $1,000.00
 Association--El Paso,
 TX
 
Muscular Dystrophy       Muscle Walk Greater Mishawaka         $1,000.00
 Association--Fort
 Wayne, IN
 
Muscular Dystrophy       Muscle Walk of Greater                $1,000.00
 Association--Fort        Mishawaka
 Wayne, IN
 
Muscular Dystrophy       Muscle Walk Western Colorado          $1,000.00
 Association--Grand
 Junction, CO
 
Muscular Dystrophy       Partners in Progress: an MDA          $5,000.00
 Association--Green       Muscle Symposium
 Bay, WI
 
Muscular Dystrophy       Muscle Walk of Green Bay              $1,000.00
 Association--Green
 Bay, WI
 
Muscular Dystrophy       Muscle Walk 2015                      $1,000.00
 Association--Greenvill
 e, SC
 
Muscular Dystrophy       Limb-Girdle Muscular                 $10,000.00
 Association--Harrisbur   Dystrophy Education Program,
 g, PA                    First Quarter, 2015
 
Muscular Dystrophy       2015 Central PA MDA Muscle            $8,000.00
 Association--Harrisbur   Summit
 g, PA
 
Muscular Dystrophy       Muscle Walk Central PA                $1,000.00
 Association--Harrisbur
 g, PA
 
Muscular Dystrophy       Muscle Walk Hawaii                    $1,500.00
 Association--Honolulu,
 HI
 
Muscular Dystrophy       Muscle Walk Houston                   $1,000.00
 Association--Houston,
 TX
 
Muscular Dystrophy       Patient and Family Healthcare         $2,000.00
 Association--Jacksonvi   Newsletter
 lle, FL
 
Muscular Dystrophy       Muscle Walk 2015                      $1,000.00
 Association--Knoxville
 , TN
 
Muscular Dystrophy       Muscle Walk                           $1,000.00
 Association--Knoxville
 , TN
 
Muscular Dystrophy       Family Engagement Events              $1,000.00
 Association--Knoxville
 , TN
 
Muscular Dystrophy       Muscle Walk                           $1,000.00
 Association--Las
 Vegas, NV
 
Muscular Dystrophy       Muscle Walk of Little Rock            $1,000.00
 Association--Little
 Rock, AR
 
Muscular Dystrophy       MDA Summer Camp                       $5,000.00
 Association--Los
 Angeles, CA
 
Muscular Dystrophy       Muscle Walk Louisville                $1,000.00
 Association--Louisvill
 e, KY
 
Muscular Dystrophy       Muscle Walk                           $1,000.00
 Association--Louisvill
 e, KY
 
Muscular Dystrophy       MDA Conference                        $1,500.00
 Association--Mancheste
 r, NH
 
Muscular Dystrophy       Muscle Walk St Louis                  $1,000.00
 Association--Maryland
 Heights, MO
 
Muscular Dystrophy       2015 Central New Jersey MDA           $8,000.00
 Association--Maywood,    Muscle Summit
 NJ
 
Muscular Dystrophy       2nd Quarter/4th Quarter Print         $2,000.00
 Association--Maywood,    Newsletters 2015
 NJ
 
Muscular Dystrophy       Muscle Walk                           $1,000.00
 Association--Memphis,
 TN
 
Muscular Dystrophy       Muscle Walk 2015                      $1,000.00
 Association--Metairie,
 LA
 
Muscular Dystrophy       Muscle Walk Baton Rouge               $1,000.00
 Association--Metairie,
 LA
 
Muscular Dystrophy       MDA South Alabama Chapter             $2,000.00
 Association--Montgomer   Quarterly Family Newsletter
 y, AL
 
Muscular Dystrophy       Muscular Dystrophy                    $2,000.00
 Association--New         Association 2015 2nd Quarter
 Haven, CT                Newsletter
 
Muscular Dystrophy       Muscle Walk Metro NY                  $1,000.00
 Association--New York,
 NY
 
Muscular Dystrophy       Muscular Dystrophy                    $2,000.00
 Association--North       Association 1st Quarter 2015
 Haven, CT                Newsletter
 
Muscular Dystrophy       18th Annual MDA Black and             $2,000.00
 Association--North       Blue Ball
 Haven, CT
 
Muscular Dystrophy       Muscular Dystrophy                    $1,500.00
 Association--North       Association 2015 3rd Quarter
 Haven, CT                Newsletter
 
Muscular Dystrophy       2015 Mohegan Sun Southern New         $1,000.00
 Association--North       England MDA Muscle Walk
 Haven, CT
 
Muscular Dystrophy       Muscle Walk of Greater                $1,000.00
 Association--Okemos,     Lansing Area
 MI
 
Muscular Dystrophy       Muscle Walk                           $1,000.00
 Association--Okemos,
 MI
 
Muscular Dystrophy       Muscle Walk 2015                      $1,000.00
 Association--Omaha, NE
 
Muscular Dystrophy       Muscle Walk Medford                   $1,000.00
 Association--Portland,
 OR
 
Muscular Dystrophy       Muscle Walk                           $1,000.00
 Association--Portland,
 OR
 
Muscular Dystrophy       Muscle Walk Raleigh                   $1,000.00
 Association--Raleigh,
 NC
 
Muscular Dystrophy       Muscle Walk 2015                      $1,000.00
 Association--Reston,
 VA
 
Muscular Dystrophy       Fall 2015 Newsletter                  $1,200.00
 Association--Rochester
 , NY
 
Muscular Dystrophy       Muscle Walk 2015                      $1,000.00
 Association--Salt Lake
 City, UT
 
Muscular Dystrophy       Muscle Walk Salt Lake City            $1,000.00
 Association--Salt Lake
 City, UT
 
Muscular Dystrophy       Muscle Walk San Antonio & 5K          $1,000.00
 Association--San         Fun Run
 Antonio, TX
 
Muscular Dystrophy       Muscle Walk Twin Cities               $1,500.00
 Association--Shrevepor
 t, LA
 
Muscular Dystrophy       Patient Newsletter                    $1,500.00
 Association--Southfiel
 d, MI
 
Muscular Dystrophy       MDA Summer Camp 2015                  $1,000.00
 Association--Spokane,
 WA
 
Muscular Dystrophy       Muscle Walk Spokane                   $1,000.00
 Association--Spokane,
 WA
 
Muscular Dystrophy       MDA Summer Camp 2015                  $1,000.00
 Association--St
 Petersburg, FL
 
Muscular Dystrophy       MDA Summer Camp 2015                  $1,000.00
 Association--St
 Petersburg, FL
 
Muscular Dystrophy       Muscle Walk Tampa Bay                 $1,000.00
 Association--St
 Petersburg, FL
 
Muscular Dystrophy       MDA Muscle Walk--Exhibit              $1,000.00
 Association--Tempe, AZ   Booth for Patient Education
 
Muscular Dystrophy       MDA Muscle Walk Tucson--              $1,000.00
 Association--Tempe, AZ   Exhibit Booth for Patient
                          Education
 
Muscular Dystrophy       Muscle Walk of Baltimore              $1,000.00
 Association--Towson,
 MD
 
Muscular Dystrophy       Muscle Walk Ark-La-Tex                $1,000.00
 Association--Tucson,
 AZ
 
Muscular Dystrophy       Muscle Walk Central New               $1,000.00
 Association--Tucson,     Jersey
 AZ
 
Muscular Dystrophy       MDA 4th Quarter Newsletter            $2,000.00
 Association--Warwick,
 RI
 
Muscular Dystrophy       Newsletter-CAMP                       $2,000.00
 Association--Westborou
 gh, MA
 
Muscular Dystrophy       Volunteer Match                       $1,000.00
 Association--Westborou
 gh, MA
 
Muscular Dystrophy       Quarterly Newsletter                  $3,000.00
 Association--Westbrook
 , ME
 
Muscular Dystrophy       Pompe Support Dinner                  $2,000.00
 Association--Westbrook
 , ME
 
Muscular Dystrophy       Pompe Awareness and Education         $1,500.00
 Association--Westbrook   Day
 , ME
 
Muscular Dystrophy       Pompe Awareness and                   $1,000.00
 Association--Westbrook   EducationDay
 , ME
 
Muscular Dystrophy       Limb-Girdle Support Group             $1,000.00
 Association--Westbrook
 , ME
 
Muscular Dystrophy       Muscle Walk Maine                     $1,000.00
 Association--Westbrook
 , ME
 
Muscular Dystrophy       2015 MDA Muscle Walk and              $2,000.00
 Association--Wilmingto   Educational Symposium
 n, NC
 
Muscular Dystrophy       Muscle Walk of Greenville and         $1,500.00
 Association--Wilmingto   Patient Educational
 n, NC                    Symposium
 
Muscular Dystrophy       Muscle Walk of Central Ohio           $1,000.00
 Association--Worthingt
 on, OH
 
Muscular Dystrophy       Muscle Walk                           $1,000.00
 Association--Worthingt
 on, OH
 
Muscular Dystrophy       Muscle Walk                           $1,000.00
 Association--Westborou
 gh, MA
 
Museum of Science        Genzyme/Museum of Science            $66,980.00
                          Teacher Sabbatical Program
                          2014
 
Museum of Science        The Science Behind the Stars         $10,000.00
                          Event
 
National Fabry Disease   2015 NFDF Education and              $45,000.00
 Foundation               Community Patient Assistance
                          Program
 
National Fabry Disease   2015 NFDF Core Patient               $40,000.00
 Foundation               Assistance Program
 
National Fabry Disease   2015 NFDF Core Patient               $40,000.00
 Foundation               Assistance Program
 
National Fabry Disease   2015 Fabry Family Camp and           $25,000.00
 Foundation               Annual Educational
                          Conference
 
National Fabry Disease   2015 Fabry Family Camp and           $25,000.00
 Foundation               Annual Educational
                          Conference
 
National Fabry Disease   2015 Fabry Family Camp and           $25,000.00
 Foundation               Annual Educational
                          Conference
 
National Fabry Disease   2015 Fabry Educational               $14,000.00
 Foundation               Meetings
 
National Fabry Disease   2015 Fabry Emergency                 $10,000.00
 Foundation               Assistance and Ancillary
                          Expense Support
 
National Fabry Disease   2015 Fabry Emergency                 $10,000.00
 Foundation               Assistance and Ancillary
                          Expense Support
 
National Fabry Disease   2015 Family Patient                   $5,000.00
 Foundation               Assistance Program
 
National Fabry Disease   2015 Family Patient                   $5,000.00
 Foundation               Assistance Program
 
National Family          RareCaregivers.org: Caring           $10,000.00
 Caregivers Association   for Rare Disease Caregivers
 DBA Caregiver Action
 Network
 
National Family          Creating the Voice: A                 $5,000.00
 Caregivers Association   Celebration of Family
 DBA Caregiver Action     Caregiving Event
 Network
 
National Gaucher         CARE Program--Patient             $1,250,000.00
 Foundation               Assistance Program
 
National Gaucher         NGF Education, Awareness and        $400,000.00
 Foundation               Resources Program for
                          Patients
 
National Gaucher         2015 National Gaucher                $25,000.00
 Foundation               Conference
 
National Kidney          Louisville Kidney Walk                $1,000.00
 Foundation Inc.
 
National Kidney          Great Chefs of the West Gala            $200.00
 Foundation Inc.
 
National Kidney          Evansville Kidney Walk                  $500.00
 Foundation of Indiana
 
National Kidney          Northwest Kidney Walk                   $500.00
 Foundation of Indiana
 
National Kidney          Northeast Indiana Kidney Walk           $500.00
 Foundation of Indiana
 
National Kidney          2015 Mardi Gras Kidney Ball           $1,000.00
 Foundation of Michigan
 
National MPS Society     National MPS Society 29th            $20,000.00
                          Annual Family Conference
 
National MPS Society     National MPS Society 29th            $15,000.00
                          Annual Family Conference
 
National MPS Society     National MPS Society 5K Walk/        $10,000.00
                          Run
 
National Multiple        Southern New York Chapter's         $100,000.00
 Sclerosis Society--New   Walk MS 2015
 York, NY
 
National Multiple        Chapter Women Against MS              $1,000.00
 Sclerosis Society--      Luncheon
 Arizona
 
National Multiple        Spring Fling/Fall Ball               $10,000.00
 Sclerosis Society--New   Socialization Programs for
 York, NY                 People with MS
 
National Multiple        Moving Forward: An                    $3,000.00
 Sclerosis Society--New   Educational Program for
 York, NY                 Those Newly Diagnosed with
                          Multiple Sclerosis
 
National Multiple        The National Multiple                 $2,500.00
 Sclerosis Society--      Sclerosis Society, Alabama--
 Alabama-Mississippi      Mississippi Chapter's MS
 Chapter                  Dinner of Champions
 
National Multiple        MS Symposium                          $1,000.00
 Sclerosis Society--
 Alabama-Mississippi
 Chapter
 
National Multiple        Arizona Chapter's Walk MS            $10,000.00
 Sclerosis Society--      2015
 Arizona Chapter
 
National Multiple        Women Against MS Luncheon--           $2,500.00
 Sclerosis Society--      Patient Wellness Program
 Brentwood, TN
 
National Multiple        Newly Diagnosed with MS               $1,150.00
 Sclerosis Society--      Meeting
 Brentwood, TN
 
National Multiple        Women's Day Out: Health,                $450.00
 Sclerosis Society--      Beauty, Wellness and MS
 Brentwood, TN
 
National Multiple        Central Virginia Chapter's           $15,000.00
 Sclerosis Society--      Walk MS 2015
 Central Virginia
 Chapter
 
National Multiple         Women on the Move Luncheon           $2,500.00
 Sclerosis Society--
 Central Virginia
 Chapter
 
National Multiple        Mind and Body Wellness                $1,000.00
 Sclerosis Society--      Educational Symposium
 Central Virginia
 Chapter
 
National Multiple         Colorado-Wyoming Chapter's          $15,000.00
 Sclerosis Society--      Walk MS 2015
 Colorado-Wyoming
 Chapter
 
National Multiple         I Ride with MS at Bike MS           $10,000.00
 Sclerosis Society--      Colorado Event
 Colorado-Wyoming
 Chapter
 
National Multiple        2015 SH & Patient Support             $8,610.00
 Sclerosis Society--      Groups
 Colorado-Wyoming
 Chapter
 
National Multiple        Optimal Health with MS--              $8,350.00
 Sclerosis Society--      Integrating Lifestyle,
 Colorado-Wyoming         Alternative & Conventional
 Chapter                  Medicine
 
National Multiple        Fitness as a Lifestyle 2015--         $4,710.00
 Sclerosis Society--      Patient Wellness Program
 Colorado-Wyoming
 Chapter
 
National Multiple        National MS Society                  $25,000.00
 Sclerosis Society--      Scholarship Program
 Denver, CO
 
National Multiple        Navigator Patient Resource           $15,000.00
 Sclerosis Society--      Program
 Gateway Area Chapter
 MS
 
National Multiple        Walk MS 2015                          $5,000.00
 Sclerosis Society--
 Gateway Area Chapter
 
National Multiple        Walk MS                              $50,000.00
 Sclerosis Society--
 Greater Illinois
 Chapter
 
National Multiple        MuckFest MS Chicago Race             $15,000.00
 Sclerosis Society--
 Greater Illinois
 Chapter
 
National Multiple        7th Annual Women on the Move          $7,000.00
 Sclerosis Society--      Luncheon
 Greater Illinois
 Chapter
 
National Multiple        Walk MS Boston                       $25,000.00
 Sclerosis Society--
 Greater New England
 Chapter
 
National Multiple        Muckfest MS Boston                   $25,000.00
 Sclerosis Society--
 Greater New England
 Chapter
 
National Multiple        Bike MS Ride the Vineyard            $10,000.00
 Sclerosis Society--
 Greater New England
 Chapter
 
National Multiple        National MS Walks Worcester           $2,000.00
 Sclerosis Society--      and Boston
 Greater New England
 Chapter
 
National Multiple        Maine Living Well with MS             $1,500.00
 Sclerosis Society--      Program
 Greater New England
 Chapter
 
National Multiple        Vermont Living Well with MS           $1,250.00
 Sclerosis Society--      Conference
 Greater New England
 Chapter
 
National Multiple        Hidden Symptoms of MS                 $1,250.00
 Sclerosis Society--      Conference
 Greater New England
 Chapter
 
National Multiple        New Hampshire Spring                  $1,250.00
 Sclerosis Society--      Education Conference
 Greater New England
 Chapter
 
National Multiple        Rhode Island Living Well with         $1,250.00
 Sclerosis Society--      MS Spring Conference
 Greater New England
 Chapter
 
National Multiple        Connecticut Walk MS 2015              $2,500.00
 Sclerosis Society--
 Hartford, CT
 
National Multiple        National MS Society South            $20,000.00
 Sclerosis Society--      Central Region BP 150 Bike
 Houston, TX              Race Event
 
National Multiple        North Texas Walk MS 2015             $18,000.00
 Sclerosis Society--
 Houston, TX
 
National Multiple        Tulsa & Central, OK Walk MS          $10,000.00
 Sclerosis Society--      2015
 Houston, TX
 
National Multiple        San Antonio MS Walk 2015             $10,000.00
 Sclerosis Society--
 Houston, TX
 
National Multiple        2015 Oklahoma Leadership             $10,000.00
 Sclerosis Society--      Events
 Houston, TX
 
National Multiple        Lydia Emily Project                  $10,000.00
 Sclerosis Society--      supporting BP 150 Bike Race
 Houston, TX              Event
 
National Multiple        North Texas Bike MS 2015              $7,500.00
 Sclerosis Society--
 Houston, TX
 
National Multiple        On The Move Luncheon program          $5,000.00
 Sclerosis Society--      to raise funds and awareness
 Houston, TX              for Multiple Sclerosis
 
National Multiple        I Ride With MS Oklahoma Bike          $5,000.00
 Sclerosis Society--      Event
 Houston, TX
 
National Multiple        Louisiana--New Orleans,               $3,500.00
 Sclerosis Society--      Shreveport, and Baton Rouge
 Houston, TX              Walk MS 2015
 
National Multiple        Bike MS Event--Midland                $3,000.00
 Sclerosis Society--
 Houston, TX
 
National Multiple        On The Move Luncheon Baton            $2,500.00
 Sclerosis Society--      Rouge
 Houston, TX
 
National Multiple        Ohio Buckeye Chapter's Walk           $5,000.00
 Sclerosis Society--      MS 2015
 Independence, OH
 
National Multiple        North Florida Walk MS 2015            $7,500.00
 Sclerosis Society--
 Jacksonville, FL
 
National Multiple        MS On the Move Luncheon               $2,500.00
 Sclerosis Society--
 Jacksonville, FL
 
National Multiple        MS On the Move Luncheon               $1,000.00
 Sclerosis Society--
 Jacksonville, FL
 
National Multiple        MS Awareness Mural                   $10,000.00
 Sclerosis Society--
 Kentucky-Southeast
 Indiana Chapter
 
National Multiple        Walk MS Kentucky                     $10,000.00
 Sclerosis Society--
 Kentucky-Southeast
 Indiana Chapter
 
National Multiple        Moving Mountains For MS: 2015         $7,500.00
 Sclerosis Society--      Family Weekend Retreat
 Kentucky-Southeast
 Indiana Chapter
 
National Multiple        Crystal Boots & Silver Spurs          $5,000.00
 Sclerosis Society--      Fundraising Event
 Kentucky-Southeast
 Indiana Chapter
 
National Multiple        Best of Louisville 2015               $3,000.00
 Sclerosis Society--      Patient Resources Event
 Kentucky-Southeast
 Indiana Chapter
 
National Multiple        Women on the Move--Patient            $1,000.00
 Sclerosis Society--      Awareness Program
 Kentucky-Southeast
 Indiana Chapter
 
National Multiple        Long Island Walk MS 2015              $5,000.00
 Sclerosis Society--
 Long Island Chapter
 
National Multiple        10th Annual Spring into               $3,000.00
 Sclerosis Society--      Awareness Luncheon
 Long Island Chapter
 
National Multiple        Southern California & Nevada         $25,000.00
 Sclerosis Society--Los   Chapter's Walk MS 2015
 Angeles, CA
 
National Multiple        40th Annual Dinner of                 $5,000.00
 Sclerosis Society--Los   Champions
 Angeles, CA
 
National Multiple        Program on Fueling Impact in          $4,000.00
 Sclerosis Society--Los   MS Research
 Angeles, CA
 
National Multiple        Lydia Emily ``Make Your Mark          $2,500.00
 Sclerosis Society--Los   on MS'' Mural Project that
 Angeles, CA              will provide hope to the
                          local MS community and
                          greatly increase public
                          awareness of MS
 
National Multiple        Dinner of Champions Northern          $2,500.00
 Sclerosis Society--Los   Nevada
 Angeles, CA
 
National Multiple        Maryland Walk MS 2015                 $7,500.00
 Sclerosis Society--
 Maryland Chapter
 
National Multiple        Walk MS 2015                          $5,000.00
 Sclerosis Society--MI
 Chapter
 
National Multiple        The 37th Annual Ambassadors          $25,000.00
 Sclerosis Society--      Ball
 National Capital
 Chapter
 
National Multiple        National Capital Chapter's           $10,000.00
 Sclerosis Society--      Walk MS 2015
 National Capital
 Chapter
 
National Multiple        National Capital Chapter's            $5,000.00
 Sclerosis Society--      Walk MS 2015
 National Capital
 Chapter
 
National Multiple        11th Annual Women On The Move         $5,000.00
 Sclerosis Society--      Luncheon
 National Capital
 Chapter
 
National Multiple        Bike MS Ride the Vine Event           $5,000.00
 Sclerosis Society--
 National Capital
 Chapter
 
National Multiple        A Day for Men Living with MS          $1,500.00
 Sclerosis Society--      Program
 National Capital
 Chapter
 
National Multiple        Bike MS 'I Ride with MS'            $600,000.00
 Sclerosis Society--New   Program
 York, NY
 
National Multiple        The International Progressive       $100,000.00
 Sclerosis Society--New   MS Alliance 2015
 York, NY
 
National Multiple        National MS Society E-               $75,000.00
 Sclerosis Society--New   Communications Program
 York, NY
 
National Multiple        North American Education             $35,000.00
 Sclerosis Society--New   Program for people with MS
 York, NY                 and their families
 
National Multiple        Knowledge is Power 2015 at           $35,000.00
 Sclerosis Society--New   Home Educational series
 York, NY
 
National Multiple        MS Navigator: Information            $25,000.00
 Sclerosis Society--New   Program
 York, NY
 
National Multiple        National MS Society                  $25,000.00
 Sclerosis Society--New   educational video
 York, NY                 programming for people with
                          MS and their families
                          through ``MS Learn Online''
 
National Multiple        2015 National MS Society,            $15,000.00
 Sclerosis Society--New   Southern NY Chapter
 York, NY                 Scholarship Program
 
National Multiple        2015 Women on the Move               $12,000.00
 Sclerosis Society--New   Program
 York, NY
 
National Multiple        2015 Gala/Dinner of Champions        $12,000.00
 Sclerosis Society--New
 York, NY
 
National Multiple        Research Symposium 2015: MS           $3,000.00
 Sclerosis Society--New   Research Discoveries:
 York, NY                 Wellness and Treatments for
                          Living Your Best Life
 
National Multiple        Medical Student Clinical              $1,500.00
 Sclerosis Society--New   Summer Fellowship
 York, NY
 
National Multiple        MS Awareness and Education           $15,000.00
 Sclerosis Society--NJ    Newsletter
 Metro Chapter
 
National Multiple        New Jersey Metro Chapter's           $10,000.00
 Sclerosis Society--NJ    Walk MS 2015
 Metro Chapter
 
National Multiple        Northern California Chapter's        $25,000.00
 Sclerosis Society--      Walk MS 2015
 Northern California
 
National Multiple        Chapter DuskBuster 5k Race            $2,500.00
 Sclerosis Society--      Event
 Northern California
 
National Multiple        Ohio Valley Chapter's Walk MS        $10,000.00
 Sclerosis Society--      2015
 Ohio Valley Chapter
 
National Multiple        Women on the Move Luncheon            $2,500.00
 Sclerosis Society--      and Fashion Show
 Ohio Valley Chapter
 
National Multiple        Lydia Emily ``Make Your Mark         $33,554.00
 Sclerosis Society--      on MS'' Mural Project that
 Oregon Chapter           will provide hope to the
                          local MS community and
                          greatly increase public
                          awareness of MS
 
National Multiple        Oregon Chapter's Walk MS 2015        $10,000.00
 Sclerosis Society--
 Oregon Chapter
 
National Multiple        Bike MS 2015: Willamette              $5,000.00
 Sclerosis Society--      Valley
 Oregon Chapter
 
National Multiple        Gala MS 2015                          $5,000.00
 Sclerosis Society--
 Oregon Chapter
 
National Multiple        Relationship Matters--Spring          $5,000.00
 Sclerosis Society--      2015
 Oregon Chapter
 
National Multiple        Greater Delaware Valley and           $7,500.00
 Sclerosis Society--      Delaware Chapter's Walk MS
 Philadelphia, PA         2015
 
National Multiple        Women Against MS Luncheon--           $2,500.00
 Sclerosis Society--      Patient Wellness Program
 Philadelphia, PA
 
National Multiple        Pennsylvania Keystone                $25,000.00
 Sclerosis Society--      Chapter's Walk MS Champaign
 Pittsburgh, PA           (to include 23 Walk Events)
 
National Multiple        Walk MS 2015                         $10,000.00
 Sclerosis Society--
 Rochester, NY
 
National Multiple        2015 National MS Society,             $7,000.00
 Sclerosis Society--      Upstate NY Chapter
 Rochester, NY            Scholarship Program
 
National Multiple        Bike MS Event                         $5,000.00
 Sclerosis Society--
 Rochester, NY
 
National Multiple        2015 MS Research Nights               $5,000.00
 Sclerosis Society--
 Rochester, NY
 
National Multiple        Champions On the Move                 $3,000.00
 Sclerosis Society--      Luncheon
 Rochester, NY
 
National Multiple        8th Annual Hudson Valley              $3,000.00
 Sclerosis Society--      Multiple Sclerosis Symposium
 Rochester, NY
 
National Multiple        2015 Health and Wellness Fair         $2,000.00
 Sclerosis Society--
 Rochester, NY
 
National Multiple        Everyday Matters: Living Your         $2,000.00
 Sclerosis Society--      Best Life with MS Program
 Rochester, NY
 
National Multiple        On the Move Luncheon program          $1,500.00
 Sclerosis Society--      to raise funds and awareness
 Rochester, NY            for Multiple Sclerosis
 
National Multiple        MS Service Day--Patient               $1,000.00
 Sclerosis Society--      Assistance Program
 Rochester, NY
 
National Multiple        Free From Falls--Patient                $750.00
 Sclerosis Society--      Wellness Program
 Rochester, NY
 
National Multiple        Utah-Southern Idaho Walk MS          $15,000.00
 Sclerosis Society--      2015
 Salt Lake City, UT
 
National Multiple        Women on the Move Luncheon            $2,500.00
 Sclerosis Society--      and Fashion Show 2015
 Salt Lake City, UT
 
National Multiple        Walk MS San Diego                    $15,000.00
 Sclerosis Society--San
 Diego, CA
 
National Multiple        28th Annual MS Dinner Charity        $10,000.00
 Sclerosis Society--San   Auction
 Diego, CA
 
National Multiple        MS Dinner Auction Hawaii              $5,000.00
 Sclerosis Society--San
 Diego, CA
 
National Multiple        UC Irvine Lunch & Learn               $4,000.00
 Sclerosis Society--San   Symposium
 Diego, CA
 
National Multiple        Challenge Walk MS                     $2,500.00
 Sclerosis Society--San
 Diego, CA
 
National Multiple        South Florida Chapter's Walk         $25,000.00
 Sclerosis Society--      MS 2015
 South Florida Chapter
 
National Multiple        MS Gala Luncheon 2015                $10,000.00
 Sclerosis Society--
 South Florida Chapter
 
National Multiple        Festival Hispano 2015--               $4,000.00
 Sclerosis Society--      Patient Awareness Program
 South Florida Chapter
 
National Multiple        Mind, Body & Soul--ESTERO             $1,500.00
 Sclerosis Society--      Event
 South Florida Chapter
 
National Multiple        Mind, Body & Soul--Boca Raton         $1,500.00
 Sclerosis Society--      Event
 South Florida Chapter
 
National Multiple        Walk MS: North Dakota Walks,          $5,500.00
 Sclerosis Society--      South Dakota Walks, and Twin
 Upper Midwest Chapter    Cities Challenge Walk
 
National Multiple        Upper Midwest Chapter's Walk          $5,000.00
 Sclerosis Society--      MS 2015
 Upper Midwest Chapter
 
National Multiple        Taste of Generosity Gala              $2,500.00
 Sclerosis Society--      Dinner
 Upper Midwest Chapter
 
National Multiple        St. Cloud MS Walk 2015                $1,000.00
 Sclerosis Society--
 Upper Midwest Chapter
 
National Multiple        Wisconsin Chapter's Walks MS         $10,000.00
 Sclerosis Society--      2015 (to include 20 Walk
 Wisconsin Chapter        Events)
 
National Multiple        Georgia Chapter's Walk MS             $5,000.00
 Sclerosis Society--      2015
 Georgia Chapter
 
National Multiple        Bike MS Cape Cod Getaway, the        $50,000.00
 Sclerosis Society--      largest MS ride in New
 Greater New England      England
 Chapter
 
National Multiple        MileStones 2015 Program Ad            $5,000.00
 Sclerosis Society-
 Greater New England
 Chapter
 
National Multiple        Greater Northwest Chapter's          $25,000.00
 Sclerosis Society-       Walk MS Events
 Greater Northwest
 Chapter
 
National Multiple        Bike MS Race Event: I Ride           $10,000.00
 Sclerosis Society-       with MS
 Greater Northwest
 Chapter
 
National Multiple        Mood & Cognition in MS: What          $8,230.00
 Sclerosis Society-       you can do--Patient Wellness
 Greater Northwest        Program
 Chapter
 
National Multiple        Northwest Chapter's Dinner of         $2,500.00
 Sclerosis Society-       Champions Gala
 Greater Northwest
 Chapter
 
National Multiple        Indiana Chapter's Walk MS             $8,500.00
 Sclerosis Society        2015
 Indiana State Chapter
 
National Multiple        Society's Financial Patient           $5,000.00
 Sclerosis Society        Assistance Program
 Indiana State Chapter
 
National Multiple        MS Navigator: Information             $5,000.00
 Sclerosis Society        Program
 Indiana State Chapter
 
National Multiple        39th Annual Dinner of                 $5,000.00
 Sclerosis Society--Los   Champions
 Angeles, CA
 
National Multiple        Everyday Matters Patient                $909.00
 Sclerosis Society--      Wellness Program
 Upstate New York
 Chapter
 
National Niemann-Pick    Hope is on the Horizon Family        $30,000.00
 Disease Foundation       Patient Services Program
 
National Organization    Portraits of Courage 2015            $50,000.00
 for Rare Disorders
 
National Organization    Volunteer Match                       $9,000.00
 for Rare Disorders
 
National Organization    Rare Disease Day Relay                $6,000.00
 for Rare Disorders
 
National Organization    NORD's Rare Diseases and             $50,000.00
 for Rare Disorders,      Orphan Products Breakthrough
 Inc.                     Summit
 
National Tay-Sachs &     Imagine & Believe 2015 Event         $10,000.00
 Allied Diseases
 Association, Inc.
 
National Tay-Sachs &     37th Annual Family Conference         $5,000.00
 Allied Diseases
 Association, Inc.
 
National Tay-Sachs &     Raising Awareness of                  $1,200.00
 Allied Diseases          Ashkenazi Jewish Genetic
 Association, Inc.        Diseases through the
                          Forward's annual genetics
                          issue
 
Nebraska Kidney          Patient & Family Education              $500.00
 Association              Day
 
Neurologic Disease       MS: Today and Tomorrow                $5,995.00
 Foundation               Caregiver Wellness Program
 
Neurologic Disease       Newly Diagnosed MS Patient            $4,995.00
 Foundation               Educational Series 2015
 
Neuropathy Action        9th Annual Neuropathy Action          $2,500.00
 Foundation               Awareness Day
 
New England Healthcare   The Nick Littlefield Health          $25,000.00
 Institute                Policy Fellowship
 
New England Healthcare   Innovators in Health Awards          $25,000.00
 Institute
 
Next Step Fund Inc.      Expansion of year-round              $10,000.00
                          programming in Song.Studio
                          and the Media Lab for youth
                          with rare genetic disorders
 
Norton Healthcare        2015 Neuro Expo                      $10,000.00
 Foundation, Inc.
 
OhioHealth Corporation   OhioHealth Multiple Sclerosis        $20,000.00
                          Patient Education Program
 
Oligonucleotide          11th Annual Meeting of the            $2,500.00
 Therapeutic Society      Oligonucleotide Therapeutics
                          Society
 
Operation Warm Inc.      Community support for Boston         $15,000.00
                          Warmth in Winter
 
Oregon Health & Science  At the Frontier & Beyond: MS          $8,850.00
 University               2015
 
Oregon Health & Science  On the Horizon: Updates in            $8,700.00
 University               Multiple Sclerosis
 
Our Space Inc.           Volunteer Match                       $1,000.00
 
Partners Healthcare      World Medical Innovation             $50,000.00
 System, Inc.             Forum--Neurosciences
 
Patient Access Network   Patient Assistance Program          $260,000.00
 Foundation               for Homozygous Familial
                          Hypercholesterolemia (HoFH)
                          Patients
 
Patient Access Network   Patient Assistance Program          $125,000.00
 Foundation               for Patients with Thyroid
                          Cancer
 
Patient Access Network   Patient Assistance Program           $50,000.00
 Foundation               for Homozygous Familial
                          Hypercholesterolemia (HoFH)
                          Patients
 
Patient Access Network   Patient Assistance Program           $50,000.00
 Foundation               for Homozygous Familial
                          Hypercholesterolemia (HoFH)
                          Patients
 
Patient Services Inc.    Fabry Financial Patient           $3,150,000.00
                          Assistance Program
 
Patient Services Inc.    Pompe Patient Assistance            $237,422.00
                          Program
 
Patient Services Inc.    Pompe Patient Assistance            $237,422.00
                          Program
 
Patient Services Inc.    MPS1 Patient Assistance             $212,778.00
                          Program
 
Patient Services Inc.    Patient Assistance Program          $212,378.00
                          for Gauchers Disease
 
Peer Health Exchange     Peer Health Exchange:                 $5,000.00
 Inc.                     Empowering Boston Youth to
                          Make Healthy Decisions
 
Perkins School for the   Perkins eLearning: Accessible        $20,000.00
 Blind                    Science Education
 
Pharmacy Quality         Development of Quality               $75,000.00
 Alliance                 Measurement Strategy for
                          Multiple Sclerosis Program
 
Phillips Brooks House    Put on a Helmet!                      $5,755.76
 Association
 Incorporated
 
Portland VA Research     PDX Patient Workshop                  $4,000.00
 Foundation Inc.
 
Pro Player Foundation    Flavors of Austin hosted by           $5,000.00
                          Earl Campbell
 
Project Eden Inc.        Volunteer Match                       $1,000.00
 
Race--Run Against        Super Sunday 5K Sponsorship          $10,000.00
 Cancer Events
 
Race to Erase MS         22nd Annual Race to Erase MS         $60,000.00
 
Resolve Community        Volunteer Match                       $1,000.00
 Counseling Center,
 Inc.
 
Rhode Island Rare        World Rare Disease Dar Art            $5,000.00
 Disease Foundation       Exhibit 2015
 
Rhode Island Rare        Beyond the Diagnosis Art              $2,500.00
 Disease Foundation       Exhibit
 
Rocky Mountain Multiple  Rocky Mountain MS Center              $5,000.00
 Sclerosis Center         Annual Gala
 
Room to Grow             Clinical Community Support            $5,000.00
                          Program
 
S S Cosmas & Damian      88th Annual East Cambridge            $2,500.00
 Society Inc.             Festival
 
Samaritans of Greater    Community Support for Youth          $25,000.00
 Boston                   Suicide Prevention Program
 
Science Club For Girls   Campus Chapters Supporting K-        $10,000.00
 Inc.                     12 Science Clubs
 
Science From Scientists  69th Annual Boston Citywide          $10,000.00
 Inc.                     Science Fair
 
Seattle Children's       MPS Family Day 2015                   $6,000.00
 Hospital Foundation
 
Special Olympics         Bio-Ball 2015                         $2,000.00
 Massachusetts Inc.
 
Stop Hunger Now, Inc.    Meal Packaging Event--Take            $3,044.08
                          Our Sons & Daughters to Work
                          Day
 
Student Clubs of HBS,    12th Annual Healthcare                $1,500.00
 Inc.                     Conference at Harvard
                          Business School
 
Temple University        Genzyme Allston/Brighton              $5,000.00
                          Biotechnology College
                          Scholarship
 
Terrapinn Inc.           World Orphan Drug Congress           $50,000.00
                          USA 2015
 
Texas Neurological       TNS 18th Annual Winter                $5,000.00
 Society                  Conference
 
THANC Foundation, Inc.   A Starry Night to benefit the         $5,000.00
                          THANC (Thyroid, Head and
                          Neck Cancer) Foundation
                          honoring R. Michael Tuttle,
                          MD
 
THANC Foundation, Inc.   A Starry Night to benefit the         $5,000.00
                          THANC (Thyroid, Head and
                          Neck Cancer) Foundation
                          honoring R. Michael Tuttle,
                          MD
 
The Boston Home, Inc.    B.Fit! Day Wellness Program          $18,000.00
 
The Boston Home, Inc.    iPads Communication System           $12,000.00
                          for Wheelchair Users--
                          Patient Assistance Program
 
The Boston Home, Inc.    The Boston Home Art Program          $10,000.00
 
The Boston Home, Inc.    Volunteer Match                       $1,000.00
 
The Community Art        Community Teen Media Program         $10,000.00
 Center
 
The Familial             FH Patient Speakers Bureau           $25,000.00
 Hypercholesterolemia     Program
 Foundation
 
The Familial             Homozygous Familial                  $20,000.00
 Hypercholesterolemia     Hypercholesterolemia (HoFH)
 Foundation               Community Program
 
The FH Foundation        2015 FH Global Summit                $25,000.00
 
The Forsyth Institute    The ForsythKids School Oral          $10,000.00
                          Health Program: Expansion to
                          serve Homeless Youth in
                          Cambridge
 
The Friends of the       Community Support of The              $4,000.00
 Hopkinton Public         Friends of the Hopkinton
 Library                  Public Library
 
The Life Sciences        Leadership Mid-Term Funding          $50,000.00
 Foundation               for Educational Programs
 
The McCourt Foundation   MS Educational Update Program        $20,000.00
 
The McCourt Foundation   McCourt Foundation Gala &            $15,000.00
                          Auction
 
The McCourt Foundation   Tour de South Shore Bike             $10,000.00
                          Event
 
The McCourt Foundation   The Immune System and The             $5,000.00
                          Brain With a Focus on MS
 
The National Cancer      Gaucher's Disease Relief              $5,000.00
 Coalition, Inc.          Patient Assistance Program
 
The Oak Clinic           2015 Diamond Run for MS               $5,000.00
 
The Posse Foundation     Community Support for Posse          $20,000.00
                          Boston's Students Program
 
Thompson Island Outward  Connections--STEM learning to        $10,000.00
 Bound Education Center   empower urban youth
 Inc.
 
Thyca Thyroid Cancer     18th International Thyroid           $30,000.00
 Survivors Association    Cancer Survivors' Conference
 Inc.
 
Thyca Thyroid Cancer     Informational Resource                $7,875.00
 Survivors Association    Support for ``After the
 Inc.                     Diagnosis, Medullary Thyroid
                          Cancer Memoirs'' to all
                          ThyCa Support Group
 
Tisch Multiple           18th Annual Patient Symposium        $30,000.00
 Sclerosis Research
 Center of New York,
 Inc.
 
Tisch Multiple           Healing MS Patient Newsletter        $15,000.00
 Sclerosis Research
 Center of New York,
 Inc.
 
Trustees of Boston       Genzyme Youth Science &               $5,050.00
 University               Engineering Workshop
                          Scholarships for U-Design
                          Program at Boston University
 
Trustees of Boston       Genzyme Allston/Brighton              $2,000.00
 University               Biotechnology College
                          Scholarship
 
Trustees of Boston       Genzyme Allston/Brighton              $2,000.00
 University               Biotechnology College
                          Scholarship
 
Trustees of Tufts        Genzyme Allston/Brighton              $5,000.00
 College                  Biotechnology College
                          Scholarship
 
Tutoring Plus of         Science & Math Enrichment             $5,000.00
 Cambridge, Inc.          Programs
 
Tutoring Plus of         Volunteer Match                       $1,000.00
 Cambridge, Inc.
 
United Pompe Foundation  Pompe Community Support              $46,500.00
                          Programs
 
United Pompe Foundation  Duke Late Onset Pompe Patient        $20,000.00
                          Meeting
 
United Way of Tri        Volunteer Match                       $1,000.00
 County Inc.
 
University of Florida    8th International Conference          $2,000.00
                          on Unstable Microsatellites
                          and Human Disease
 
University of            Massachusetts STEM Summit            $10,000.00
 Massachusetts            2015: Promising Practices,
                          Proven Results
 
University of            Student Success Program for         $200,000.00
 Massachusetts            UMass Boston, College of
 Foundation Inc.          Science and Mathematics
 
University of Southern   Genzyme Allston/Brighton              $5,000.00
 California               Biotechnology College
                          Scholarship
 
Urban Kidney Alliance,   Prescription Medication                 $500.00
 Inc.                     Assistance Program (PMAP)
 
Veterans Inc.            Volunteer Match                       $1,000.00
 
Visiting Nurse           Heroes in Health Care Gala           $10,000.00
 Association of Boston
 & Affiliates
 
Weill Medical College    Talk MS Program                      $10,000.00
 of Cornell University
 
West County MS Center    10th Annual Trivia and                $7,500.00
                          Auction
 
West End House Boys and  Volunteer Match                       $1,000.00
 Girls Club
 
WGBH                     WGBH Pledge Night                    $12,000.00
 
Whitehead Institute for  Whitehead Institute's 2015           $10,000.00
 Biomedical Research      CampBio Program
 
Whitehead Institute for  Whitehead Institute's 2016           $10,000.00
 Biomedical Research      CampBio Program
 
Women's Lunch Place      Community Support for Meals          $35,000.00
                          Program
 
Worcester County Food    Volunteer Match                       $1,000.00
 Bank Inc.
 
Worcester Polytechnic    Genzyme Allston/Brighton              $1,000.00
 Institute                Biotechnology College
                          Scholarship
 
WriteBoston              STEM Teacher Excellence:             $10,000.00
                          Powered By Genzyme
 
Wylder Nation            2nd Annual Living Like a             $10,000.00
 Foundation               Warrior Gala
 
YMCA of Greater Boston   Oak Square YMCA--Summer Day          $15,000.00
                          Camp Scholarship
 


                  Sponsorships and Charitable Donations
                       1st Jan 2016-31st Dec 2016
    Sanofi US and its affiliate Genzyme Corporation are committed to
   supporting sponsorships for specific activities and initiatives of
    healthcare organizations and institutions, independent medical or
professional societies, trade organizations and organized patient groups
  to improve patient care and provide information to the medical and/or
  patient communities. The goal of our charitable giving approach is to
 fund general operational support for patient/disease organizations, or
program support for community-based organizations. Sanofi US and Genzyme
    Corporation are part of the Sanofi Group, a global pharmaceutical
                                company.
 Applicant names are provided by the requestor. If applicants apply as a
  group for a single activity; all applicants may be not be identified
 above. ``Funding Amount'' is the amount that the Company funded during
  2015 identified above. ``Funding Amount'' does not include funds that
   may have been provided by other affiliated Sanofi Company Entities
                         (e.g., Sanofi Pasteur).
 
   Recipient Name(s)             Activity Title          Funding Amount
 
Acid Maltase Deficiency  General Operating Support            $48,000.00
 Association Inc.
 
ACTRIMS                  Congress Sponsorships                $30,000.00
 
Allston Brighton         Feastworthy: Pilot Prepared          $15,000.00
 Community Development    Meals Delivery Program
 Corporation
 
American Academy of      Congress Sponsorships               $482,897.00
 Neurology Institute
 
American Academy of      Palatucci Advocacy Leadership        $50,000.00
 Neurology Institute      Forum
 
American Academy of      Brain Health Fair                     $7,500.00
 Neurology Institute
 
American Academy of      Fellows Scholarship Fund             $20,000.00
 Neurology Institute
 
American Academy of      Residents Scholarship Fund           $20,000.00
 Neurology Institute
 
American Academy of      Emerging Leaders Program             $20,000.00
 Neurology Institute
 
American Association of  Congress Sponsorships                 $4,300.00
 Clinical
 Endocrinologists
 
American Association of  Fabry Family Member Testing         $164,970.00
 Kidney Patients          and Education Project
 
American Autoimmune and  50 Cents for 50 Million               $5,000.00
 Related Diseases         Laughs Campaign
 Association
 
American Brain           Patient Advocacy Organization         $5,000.00
 Coalition                Membership Sponsorship
 
American Cancer Society  Volunteer Match                       $1,000.00
 
American Cancer Society  Volunteer Match                      $11,000.00
 
American Chemical        Recovery of Biological                $5,000.00
 Society Merck and Co     Products XVII Conference
 Inc.
 
American Chemical        Biochemical Technology ACS            $5,000.00
 Society Merck and Co     National Meeting
 Inc.
 
American College of      Congress Sponsorships                $50,875.00
 Medical Genetics and
 Genomics
 
American Red Cross of    American Red Cross Blood              $5,000.00
 Massachusetts            Services
 
American Red Cross of    American Red Cross of                 $5,000.00
 Massachusetts            Massachusetts Women Who Care
                          Breakfast
 
American Thyroid         Congress Sponsorships                 $3,000.00
 Association
 
American Thyroid         Congress Sponsorships                $15,000.00
 Association
 
ANERA (American Near     ANERA Annual Dinner                   $5,000.00
 East Refugee Aid)
 
Angel's Hands            Family Assistance Program             $5,000.00
 Foundation
 
Ann & Robert H. Lurie    MPS Patient and Family                $2,000.00
 Children's Hospital of   Conference
 Chicago
 
Arthritis Foundation     Orange County & Inland Empire         $2,500.00
                          Jingle Bell Run
 
Assistance Fund Inc.     Patient Assistance Program        $7,750,000.00
                          for MS
 
Association For          Annual Conference; Family             $6,000.00
 Glycogen Storage         Assistance; The Ray
 Disease                  (newsletter)
 
Association For          Annual Conference; Family             $6,000.00
 Glycogen Storage         Assistance; The Ray
 Disease                  (newsletter)
 
Barth Syndrome           Barth Syndrome Foundation             $2,000.00
 Foundation               Conference
 
Batten Disease Support   NCL Congress Boston                   $5,000.00
 And Research
 Association
 
Berkshire Resource       8th Annual GALA Fundraiser            $5,000.00
 Project
 
Berkshire Resource       When IWalk - An MS Story              $8,000.00
 Project
 
Big Brothers Big         MySTEM--Mentoring Youth in           $10,000.00
 Sisters Of Central       Science, Technology,
 Mass Metrowest Inc.      Engineering, and Mathematics
 
Biomedical Science       Hope Scholarship                      $7,500.00
 Careers Program
 
Biomedical Science       Evening of Hope                      $75,000.00
 Careers Program
 
Biotechnology            BIO Patient and Health               $10,000.00
 Innovation               Advocacy Summit
 Organization
 
Boston Area Rape Crisis  Community Program                    $25,000.00
 Center
 
Boston Area Rape Crisis  Advocacy Program                     $25,000.00
 Center
 
Boston College Trustees  Allston Brighton College              $2,000.00
                          Scholarship
 
Boston College Trustees  Allston Brighton College              $4,000.00
                          Scholarship
 
Boston Educational       Boston Public Schools Science        $10,000.00
 Development              Fair
 Foundation, Inc.
 
Boston Health Care For   Life Essentials for Homeless         $35,000.00
 The Homeless Program     Patients
 Inc.
 
Boston Health Care For   Volunteer Match                       $1,000.00
 The Homeless Program
 Inc.
 
Boston Health Care For   General Operating Support            $10,000.00
 The Homeless Program
 Inc.
 
Boston Partners in       Power Lunch Program                   $6,000.00
 Education, Inc.
 
Boston Private Industry  Corporate Contributions              $15,000.00
 Council                  Campaign
 
Boston Private Industry  Volunteer Match                       $1,000.00
 Council
 
Bottom Line              Boston STEM Success Program          $15,000.00
 
Bottom Line              Volunteer Match                       $1,000.00
 
Boys and Girls Clubs of  Staffing & Transportation for        $25,000.00
 MetroWest                Membership at BGCMW's
                          Framingham Clubhouse
 
Boys and Girls Clubs of  Volunteer Match                       $1,000.00
 MetroWest
 
Boys and Girls Clubs of  Volunteer Match                       $4,000.00
 MetroWest
 
Boys and Girls Clubs of  Volunteer Match                       $1,000.00
 MetroWest
 
Boys and Girls Clubs of  Bids for Kids Auction & Gala         $10,000.00
 MetroWest
 
Boys and Girls Clubs Of  Great Pumpkin Glow                    $6,000.00
 Middlesex County Inc.
 
BPE                      Boston Teacher Residency:            $15,000.00
                          Putting Students at the
                          Center of STEM Teacher
                          Training
 
Breakthrough Greater     Full STEAM Ahead Program With        $10,000.00
 Boston                   Low-Income Students
 
Brian J. Honan           Brian Honan 5K Road Race              $2,500.00
 Charitable Fund
 
California Association   Congress Sponsorships                 $1,500.00
 of Physician Groups
 (CAPG)
 
California Association   Congress Sponsorships                 $1,000.00
 of Physician Groups
 (CAPG)
 
California District      Congress Sponsorships                 $3,000.00
 American Academy of
 Pediatrics
 
California Pharmacists   Congress Sponsorships                 $1,500.00
 Association
 Educational Foundation
 
Cambridge Chamber of     Women in Business Programming         $4,350.00
 Commerce                 Series Sponsor
 
Cambridge Health         Volunteer Match                       $1,000.00
 Alliance Foundation
 Inc.
 
Cambridge School         Volunteer Match                       $1,000.00
 Volunteers, Inc.
 
Cambridge School         Volunteer Match                      $15,825.00
 Volunteers, Inc.
 
Cambridge School         Volunteer Match                      $13,755.00
 Volunteers, Inc.
 
Cambridge School         Community Program                    $11,000.00
 Volunteers, Inc.
 
Cambridge School         Community Program                    $11,000.00
 Volunteers, Inc.
 
Camp Korey               Metabolic Disorders Family            $5,000.00
                          Weekend Camp
 
Can Do Multiple          JUMPSTART Programs                  $60,000.00
 Sclerosis
 
Can Do Multiple          Annual Autumn Benefit for Can         $5,000.00
 Sclerosis                Do Multiple Sclerosis
 
Can Do Multiple          Vertical Express for Can Do          $30,000.00
 Sclerosis                MS
 
Can Do Multiple          Annual Autumn Benefit                $10,000.00
 Sclerosis
 
Can Do Multiple          CAN DO Program                      $60,000.00
 Sclerosis
 
Can Do Multiple          TAKE CHARGETM Program                $37,500.00
 Sclerosis
 
Case Management Society  CMSA 26th Annual Conference &         $4,650.00
 of America               Expo
 
Case Management Society   Congress Sponsorships               $14,000.00
 of America
 
Case Management Society  Congress Sponsorships                 $5,500.00
 of America
 
Case Management Society  New Frontiers of                      $1,050.00
 of New England           Technological Advancement
                          Program
 
Case Management Society  Corporate Sponsorship of              $1,250.00
 of New England           CMSNE
 
Case Management Society  Creativity, Inspiration &             $1,000.00
 of New England           Collaboration: Building
                          Blocks of Successful
                          Leadership
 
CASSS--An International  WCBP--20th Symposium                  $7,500.00
 Separation Science
 Society
 
Charles River Community  Mom & Baby Program                   $15,000.00
 Health
 
Charles River            Volunteer Match                       $1,000.00
 Conservancy
 
Charles River            Volunteer Match                       $4,000.00
 Conservancy
 
Chelsea Jewish Nursing   ALS & MS Walk for Living              $2,500.00
 Home Foundation, Inc.
 
Childrens Gaucher        Gaucher Related Research Fund        $75,000.00
 Research Fund
 
Children's Hospital      La Gala de Milagros para              $5,000.00
 Boston                   Ninos
 
Children's Hospital      Volunteer Match                       $1,000.00
 Boston
 
Children's Hospital of   Lysosomal Day at The                 $16,370.33
 Philadelphia             Philadelphia Zoo
 Foundation
 
Chronic Disease Fund,    Medullary Thyroid Cancer            $300,000.00
 Inc DBA Good Days from   Patient Assistance Program
 CDF
 
Chronic Disease Fund,    Medullary Thyroid Cancer            $150,000.00
 Inc DBA Good Days from   Patient Assistance Program
 CDF
 
Church Hillers Inc.      Volunteer Match                       $1,000.00
 
Cincinnati Children's    Meeting for Patients with             $5,000.00
 Hospital Medical         Fabry Disease
 Center
 
Citizen Schools          Expanding STEM Learning at           $15,000.00
                          Boston Schools
 
Citizen Schools          Deepening the Impact of STEM         $15,000.00
                          Education
 
City Sprouts, Inc.       CitySprouts Middle School             $8,000.00
                          Program in Cambridge
 
City Sprouts, Inc.       CitySprouts Middle School             $8,000.00
                          Program
 
Cleveland Clinic         Multiple Sclerosis (MS)              $10,125.00
 Foundation               Promoting Wellness and
                          Healthy Lifestyle
 
Community Boating, Inc.  Universal Access Program 2016        $15,000.00
 
Community Farms          Fresh Food Access Program            $15,000.00
 Outreach
 
Community Living and     The Giving Tree Campaign              $6,500.00
 Support Services, Inc.
 
Community Rowing, Inc.   Let's Row Boston                     $10,000.00
 
Community Servings,      Pie in the Sky                       $10,000.00
 Inc.
 
Consortium of MS         Congress Sponsorships                 $5,000.00
 Centers
 
Courageous Parents       Patient Education and                 $7,000.00
 Network                  Awareness Program
 
Cradles To Crayons Inc.  Ready for School                     $20,000.00
 
Cradles To Crayons Inc.  General Operating Support            $10,000.00
 
Cradles To Crayons Inc.  Volunteer Match                       $1,000.00
 
Cystic Fibrosis          Volunteer Match                       $4,000.00
 Foundation
 
Cystic Fibrosis          Uncork the Cure                      $10,000.00
 Foundation
 
Damon Runyon Cancer      General Operating Support             $5,000.00
 Research Foundation
 
DEAF, Inc.--             Community Program                    $10,000.00
 Developmental
 Evaluation and
 Adjustment Facilities,
 Inc.
 
Dimock Community Health  29th Annual Steppin' Out for         $25,000.00
 Center                   The Dimock Center
 
Dimock Realty            Building the Road to Recovery        $50,000.00
 Corporation              Campaign
 
Direct Relief            Patient Assistance Fund for          $10,000.00
 International            Rare Diseases
 
Direct Relief            Patient Assistance Fund for           $5,000.00
 International            Rare Diseases
 
DPC Education Center     Fabry Disease Newsletter             $25,000.00
                          Support
 
Duke University          Patient Assistance Program          $400,000.00
 
Duke University          Hospitals Patient Assistance        $224,000.00
                          Program
 
East End House Inc.      Generating and Evaluating New        $20,000.00
                          Adventures in Science After
                          School (GENASAS)
 
East End House Inc.      Generating and Evaluating New        $20,000.00
                          Adventures in Science After
                          School (GENASAS)
 
Engineering Conferences  Cell Culture Engineering XV          $10,000.00
 International            Conference
 
EveryLife Foundation     Community Congress                   $15,000.00
 for Rare Diseases
 
EveryLife Foundation     Rare Disease Advocacy Program        $20,000.00
 for Rare Diseases
 
EveryLife Foundation     Rare Voice Awards                    $15,000.00
 for Rare Diseases
 
EveryLife Foundation     Patient Education and                 $5,000.00
 for Rare Diseases        Awareness Program
 
EveryLife Foundation     Community Congress                    $5,000.00
 for Rare Diseases
 
Fabry Support &          Fabry Support &Information           $30,000.00
 Information Group        Group Patient Assistance
                          Fund Program
 
Fabry Support &          Fabry Support & Information         $100,000.00
 Information Group        Group General Operating
                          Support
 
Fabry Support &          Fun Run/Walk St. Louis, MO            $1,500.00
 Information Group
 
Fabry Support &          FSIG Expert Fabry Conference         $50,000.00
 Information Group
 
Families of SMA          Annual SMA Conference                $10,000.00
 
Family Promise           Keep the Promise, Food                $2,500.00
 Metrowest Inc.           Program for the Homeless
 
Florida Society of       Congress Sponsorships                $15,000.00
 Rheumatology
 
Food For Free            Community Program                     $1,000.00
 Committee, Inc.
 
Foundation Fighting      Volunteer Match                       $2,000.00
 Blindness Inc.
 
Framingham Townwide Pto  Volunteer Match                       $1,000.00
 Council
 
Franciscan Hospital For  Adaptive Sports Program              $10,000.00
 Children Inc.
 
Friends of Resiliency    Community Program                    $10,000.00
 for Life Inc.
 
Friends of Resiliency    Volunteer Match                       $1,000.00
 for Life Inc.
 
Generation Citizen Inc.  Spring and Fall Civics Day            $5,000.00
 
Genetic Alliance Inc.    Industry Program                     $20,000.00
 
Girl Scouts of Eastern   Girls Building Self-eSTeEM           $10,000.00
 Massachusetts Inc.
 
Girl Scouts of Eastern   Volunteer Match                       $1,000.00
 Massachusetts Inc.
 
Girl Scouts of Eastern   Volunteer Match                       $1,000.00
 Massachusetts Inc.
 
Global Genes             RARE Tribute To Champions of         $25,000.00
                          Hope
 
Global Genes             RARE Webinars & RARE Toolkits        $30,000.00
 
Global Genes             Patient Assistance Program           $20,000.00
 
Global Genes             RARE Patient Advocacy Summit         $25,000.00
 
Gordon Research          Barriers of the Central               $2,000.00
 Conferences              Nervous System Gordon
                          Research Conference
 
Greater Boston Chamber   Annual Meeting                       $10,000.00
 of Commerce
 
Habitat For Humanity     Home Build for Four Low-             $20,000.00
 Metrowest--Greater       Income Families Program
 Worcester Inc.
 
Habitat For Humanity     Volunteer Match                       $1,000.00
 Metrowest--Greater
 Worcester Inc.
 
Habitat For Humanity     Volunteer Match                       $1,500.00
 Metrowest--Greater
 Worcester Inc.
 
Habitat For Humanity     Volunteer Match                       $2,000.00
 Metrowest--Greater
 Worcester Inc.
 
Habitat For Humanity     High Heels and Hard Hats              $7,500.00
 Metrowest - Greater      Auction and Gala
 Worcester Inc.
 
Harvard College          Allston Brighton College              $2,000.00
                          Scholarship
 
Health Care For All      Public Education Campaign to         $15,000.00
 Inc.                     Improve Access to Health
                          Care in Framingham
 
Health Resources In      The Leaders through                  $20,000.00
 Action Inc.              Education, Action and Hope
                          (LEAH) Project
 
Health Resources in      The Leaders through                  $20,000.00
 Action Inc.              Education, Action, and Hope
                          (LEAH) Project
 
Hearts & Noses Hospital  Hospital Clown Visits to Ill         $15,000.00
 Clown Troupe Inc.        and Disabled Children in
                          Greater Boston
 
Hereditary Disease       Milton Wexler Celebration of          $5,000.00
 Foundation               Life Symposium
 
Holy Name Health Care    MS Awards Reception                   $2,500.00
 Foundation Inc.
 
Holy Name Health Care    19th Annual spring Fling to           $5,000.00
 Foundation Inc.          benefit MS
 
Holy Name Health Care    MS Awards Reception                   $5,000.00
 Foundation Inc.
 
Horizons for Homeless    18th Annual Women's Breakfast         $5,000.00
 Children
 
Huntington's Disease     Patient Education and                 $5,000.00
 Society of America       Awareness Program
 
Huntington's Disease     Huntington's Disease Society          $2,000.00
 Society of America       of America 31st Annual
                          Convention
 
International Institute  Patient Navigation Services          $10,000.00
 of New England           for Refugees in Boston
 
International Institute  Golden Door Award Gala               $10,000.00
 of New England
 
International            Stress--You Can't Avoid It,          $10,000.00
 Organization of          But You Can Manage It!
 Multiple Sclerosis
 Nurses
 
International            Annual Meeting IOMSN Dinner          $30,000.00
 Organization of
 Multiple Sclerosis
 Nurses
 
International            MS Perspectives                      $75,000.00
 Organization of
 Multiple Sclerosis
 Nurses
 
Italian Home For         Annual Gala                           $5,000.00
 Children Inc.
 
Jewish Family Service    Patient Navigator Program            $15,000.00
 of Metrowest Inc.
 
Jewish Family Service    Patient Navigator Program            $15,000.00
 of Metrowest Inc.
 
Jewish Genetic Disease   Community and Rabbinic                  $500.00
 Consortium (JGDC)        Education for Jewish Genetic
                          Diseases
 
Just-A-Start             St. Patrick's Fund                    $5,000.00
 Corporation
 
Just-A-Start             Biomedical Careers Program           $22,950.00
 Corporation
 
LGMD2D Foundation        Patient Assistance Program          $650,000.00
 
LGMD2D Foundation        Patient Assistance Program          $600,000.00
 
Light of Life            Light of Life Foundation             $40,000.00
 Foundation               Program
 
Little Brothers/Friends  Community Program                     $7,500.00
 of the Elderly
 
Louisiana Association    Congress Sponsorships                 $5,285.00
 of Health Plans
 
MagellanRx Management    Congress Sponsorships                 $5,000.00
 
Manchaug Pond            Volunteer Match                       $1,000.00
 Association
 
March of Dimes           Volunteer Match                       $2,000.00
 
March of Dimes           Black Ties for Babies                $10,000.00
 
March of Dimes           March for Babies                     $15,000.00
 
Margaret Fuller          Please Help a Crumbling              $20,000.00
 Neighborhood House       Community Resource
 
Margaret Fuller          Margaret Fuller Kids Summer          $15,000.00
 Neighborhood House       Explorations Program
 
Mass Insight Education   Advanced Placement (AP)              $15,000.00
 and Research Institute   Science, Technology,
 Inc.                     Engineering, and Math (STEM)
                          and English Program
 
Massachusetts Bay        STEM Mentor Program (SMP)            $37,000.00
 Community College
 Foundation
 
Massachusetts            Congress Sponsorships                $25,000.00
 Biotechnology Council
 
Massachusetts            Patient Advocacy Summit              $10,000.00
 Biotechnology Council
 
Massachusetts            MassBio Annual Meeting               $10,000.00
 Biotechnology Council
 
Massachusetts            2016 MassBio Policy                   $5,000.00
 Biotechnology Council    Leadership Breakfast
 
Massachusetts            Volunteer Match                       $1,000.00
 Biotechnology
 Education Foundation
 Inc.
 
Massachusetts            BioTeach                             $50,000.00
 Biotechnology
 Education Foundation
 Inc.
 
Massachusetts            Volunteer Match                       $1,000.00
 Biotechnology
 Education Foundation
 Inc.
 
Massachusetts            Champions for Biotechnology           $2,500.00
 Biotechnology            Education Program
 Education Foundation
 Inc.
 
Massachusetts Black      Massachusetts Black Women             $5,000.00
 Women Attorneys          Attorneys 35th Anniversary
 Foundation Inc.          Celebration
 
Massachusetts College    Next Generation of Women             $10,000.00
 of Pharmacy and Health   Leaders in STEM
 Sciences
 
Massachusetts Institute  Cambridge Science Festival            $5,000.00
 of Technology
 
Massachusetts Outdoor    Volunteer Match                       $1,000.00
 Heritage Foundation
 Inc.
 
Massachusetts State      Massachusetts State Science &        $50,000.00
 Science and              Engineering Fair
 Engineering Fair, Inc.
 
Mattel Children's        Educational Seminars for             $59,000.00
 Hospital UCLA            Patients with Fabry Disease
 
Mercy Foundation         Multiple Sclerosis                   $25,000.00
                          Achievement Center Wellness
                          Education Programs
 
Metrowest Free Medical   Expanding Access to Women's          $10,000.00
 Program Inc.             Health Care and Health
                          Education in Framingham
 
Miami Childrens Health   Education and Outreach                $5,000.00
 System Foundation Inc.   Activities of Jewish Genetic
                          and Pan-Ethnic Diseases
 
Mid America MS           The Race to Nowhere                   $5,000.00
 Achievement Center
 
Mid America MS           Your MS Depression Toolkit            $8,210.00
 Achievement Center
 
Mint For Mounts Inc.     Volunteer Match                       $1,000.00
 
MITS Inc.                STEM Professional Development        $20,000.00
                          Institutes for teachers
 
MITS Inc.                Professional Development             $20,000.00
                          Institutes for teachers
 
MS Cure Fund             Women Thriving with MS--How         $125,000.00
                          to be a partner, a mother, a
                          woman--FIRST
 
MS Cure Fund             Lifestyle Management Programs        $13,500.00
                          Spring
 
MS Cure Fund             eNewsletter                          $24,000.00
 
MS Cure Fund             Patient Education and                $22,580.00
                          Awareness Program
 
MS Hope for a Cure Inc.  MS Hope Day                          $10,000.00
 
MS Views and News Inc.   Wheelchairs for Charity               $6,000.00
 
MS Views and News Inc.   Effective Communication              $19,775.00
                          Program
 
MS Views and News Inc.   Champions Tackling MS Awards          $5,000.00
                          Dinner Gala
 
MS Views and News Inc.   Congress Sponsorships                 $7,900.00
 
MS Views and News Inc.   MS Views and News 6th Annual          $3,500.00
                          Bowlathon Fundraiser
 
MS Views and News Inc.   Patient Education and                $10,406.75
                          Awareness Program
 
MS Views and News Inc.   The Evolution of MS Care--           $14,200.00
                          Making Impacts on Health and
                          Wellness
 
MS Views And News Inc.   Patient Education and                $26,910.75
                          Awareness Program
 
MSWorld, Inc.            MSWorld Conference Coverage          $12,000.00
 
Multiple Sclerosis       Patient Assistance Program          $125,000.00
 Association of America
 
Multiple Sclerosis       MSAA Cooling Equipment               $15,000.00
 Association of America   Distribution Program
 
Multiple Sclerosis       Patient Assistance Program           $50,000.00
 Association of America
 
Multiple Sclerosis       Navigating MS Program                $75,000.00
 Association of America
 
Multiple Sclerosis       ``MS Health and Wellness''           $20,000.00
 Association of America   Program
 
Multiple Sclerosis       Patient Education and               $105,000.00
 Association of America   Awareness Program
 
Multiple Sclerosis       MSAA's Improving Lives               $10,000.00
 Association of America   Benefit
 
Multiple Sclerosis       MSAA Annual Healthcare               $24,887.00
 Association of America   Advisory Council Summit
 
Multiple Sclerosis       Patient Education and                $17,409.50
 Association of America   Awareness Program
 
Multiple Sclerosis       MS Fest                              $10,000.00
 Center of Georgia
 
Multiple Sclerosis       Health, Hope & Hops                   $7,000.00
 Center of Georgia
 
Multiple Sclerosis       Health, Hope & Hops                   $7,000.00
 Center of Georgia
 
Multiple Sclerosis       Multiple Sclerosis                   $50,000.00
 Foundation               Foundation's Assistive
                          Technology Program
 
Multiple Sclerosis       EmpowerSource Support Group          $28,000.00
 Foundation               Newsletter
 
Multiple Sclerosis       Chapter Meetings Support              $7,000.00
 Foundation
 
Multiple Sclerosis       National March MS Education          $40,000.00
 Foundation               and Awareness Monthr 2016
 
Multiple Sclerosis       MS Dinner of Hope                     $1,500.00
 Resources of Central
 New York, Inc.
 
Multiple Sclerosis       Mission Steps Walk & MS               $8,000.00
 Resources of Central     Awareness Day
 New York, Inc.
 
Muscular Dystrophy       MDA Summer Camp                       $3,500.00
 Association
 
Muscular Dystrophy       Volunteer Match                       $1,000.00
 Association
 
Muscular Dystrophy       Care Services Program                 $1,500.00
 Association
 
Muscular Dystrophy       Live Unlimited Program               $30,000.00
 Association
 
Muscular Dystrophy       Patient Assistance Program          $700,000.00
 Association
 
Muscular Dystrophy       MDA MuscleWalk Fresno                 $1,000.00
 Association
 
Muscular Dystrophy       Muscular Dystrophy                    $2,000.00
 Association              Association, Second Quarter
                          Newsletter
 
Muscular Dystrophy       Muscular Dystrophy                    $2,000.00
 Association              Association 2nd Quarter
                          Newsletter
 
Muscular Dystrophy       Quarterly Newsletter                  $5,000.00
 Association
 
Muscular Dystrophy       Kids Art Auction                      $1,500.00
 Association
 
Muscular Dystrophy       Patient Assistance Program            $2,000.00
 Association
 
Muscular Dystrophy       Patient, Provider and Family          $2,000.00
 Association              Healthcare Newsletter
 
Muscular Dystrophy       Muscular Dystrophy                    $2,500.00
 Association              Association of Montana
                          Summer Camp
 
Muscular Dystrophy       MDA Summer Camp                       $2,500.00
 Association
 
Muscular Dystrophy       MDA Summer Camp                       $2,500.00
 Association
 
Muscular Dystrophy       Newsletter                            $2,500.00
 Association
 
Muscular Dystrophy       Muscular Dystrophy                    $2,000.00
 Association              Association Quarter
                          Newsletter
 
Muscular Dystrophy       Patient Education and                 $1,000.00
 Association              Awareness Program
 
Muscular Dystrophy       MDA Black N Blue comedy event         $2,500.00
 Association
 
Muscular Dystrophy       MDA MuscleWalk Dayton                 $1,000.00
 Association
 
Muscular Dystrophy       MDA MuscleWalk Albany                 $1,000.00
 Association
 
Muscular Dystrophy       MDA Wisconsin Muscle Summit           $8,000.00
 Association
 
Muscular Dystrophy       MDA MuscleWalk MA                     $1,000.00
 Association
 
Muscular Dystrophy       MDA Central Texas MuscleWalk          $1,000.00
 Association
 
Muscular Dystrophy       MDA MuscleWalk of Greater             $1,000.00
 Association              Cincinnati
 
Muscular Dystrophy       MDA MuscleWalk MN                     $1,000.00
 Association
 
Muscular Dystrophy       MDA MuscleWalk of Green Bay           $1,000.00
 Association
 
Muscular Dystrophy       MDA MuscleWalk Knoxville              $1,000.00
 Association
 
Muscular Dystrophy       MDA MuscleWalk Omaha                  $1,000.00
 Association
 
Muscular Dystrophy       MDA MuscleWalk Jacksonville           $1,000.00
 Association
 
Muscular Dystrophy       MDA MuscleWalk Hawaii                 $1,000.00
 Association
 
Muscular Dystrophy       Passport to a Cure Program            $1,500.00
 Association
 
Muscular Dystrophy       MDA MuscleWalk St. George             $1,000.00
 Association              Utah
 
Muscular Dystrophy       MDA MuscleWalk Miami                  $1,000.00
 Association
 
Muscular Dystrophy       MDA Muscle Team                       $3,000.00
 Association
 
Muscular Dystrophy       3rd and 4th Quarter                   $3,000.00
 Association              Newsletter
 
Muscular Dystrophy       MDA of Maine MuscleWalk               $1,000.00
 Association
 
Muscular Dystrophy       MDA MuscleWalk Kansas City            $1,000.00
 Association
 
Muscular Dystrophy       Fourth Quarter Newsletter             $2,000.00
 Association
 
Muscular Dystrophy       MDA MuscleWalk Northwest              $1,000.00
 Association              Indiana
 
Muscular Dystrophy       MDA MuscleWalk Tucson                 $1,000.00
 Association
 
Muscular Dystrophy       MDA MuscleWalk Houston                $1,000.00
 Association
 
Muscular Dystrophy       MDA MuscleWalk of Metro NY            $1,000.00
 Association
 
Muscular Dystrophy       MDA MuscleWalk NH                     $1,000.00
 Association
 
Muscular Dystrophy       MDA MuscleWalk of Raleigh             $1,000.00
 Association
 
Muscular Dystrophy       MDA MuscleWalk of Northwest           $1,000.00
 Association              Arkansas
 
Muscular Dystrophy       3rd Quarter Newsletter                $3,000.00
 Association
 
Muscular Dystrophy       MDA MuscleWalk of Columbia            $1,000.00
 Association
 
Muscular Dystrophy       3rd Quarter Newsletter                $5,000.00
 Association
 
Muscular Dystrophy       MDA MuscleWalk of Greater             $1,000.00
 Association              Madison
 
Muscular Dystrophy       MDA MuscleWalk FL                     $1,000.00
 Association
 
Muscular Dystrophy       MDA MuscleWalk Amarillo               $1,000.00
 Association
 
Muscular Dystrophy       MDA MuscleWalk of Manasota            $1,000.00
 Association
 
Muscular Dystrophy       MDA MuscleWalk MO                     $1,000.00
 Association
 
Muscular Dystrophy       Northern California Muscle            $8,000.00
 Association              Summit
 
Muscular Dystrophy       MDA MuscleWalk of Palm Beach          $1,000.00
 Association
 
Muscular Dystrophy       MDA MuscleWalk FL                       $500.00
 Association
 
Muscular Dystrophy       MDA MuscleWalk WA                     $1,000.00
 Association
 
Muscular Dystrophy       2nd Annual Nashville Muscle           $1,000.00
 Association              Team Gala
 
Muscular Dystrophy       MDA MuscleWalk Hartford/New           $1,000.00
 Association              Haven
 
Muscular Dystrophy       MDA MuscleWalk of Colorado            $1,000.00
 Association              Springs
 
Muscular Dystrophy       MDA MuscleWalk of San Diego           $1,000.00
 Association
 
Muscular Dystrophy       MDA MuscleWalk Tri-Cities             $1,000.00
 Association
 
Muscular Dystrophy       MDA MuscleWalk Chattanooga            $1,000.00
 Association
 
Muscular Dystrophy       MDA MuscleWalk Greater Lehigh         $1,000.00
 Association              Valley
 
Muscular Dystrophy       MDA MuscleWalk Midland                $1,000.00
 Association
 
Muscular Dystrophy       MDA MuscleWalk Lubbock                $1,000.00
 Association
 
Muscular Dystrophy       MDA MuscleWalk Orlando                $1,000.00
 Association
 
Muscular Dystrophy       MDA MuscleWalk South Alabama          $1,000.00
 Association
 
Muscular Dystrophy       MDA MuscleWalk of Peoria              $1,000.00
 Association
 
Muscular Dystrophy       MDA MuscleWalk of Greater             $1,000.00
 Association              Baton Rouge
 
Muscular Dystrophy       MDA MuscleWalk of Greater New         $1,000.00
 Association              Orleans
 
Muscular Dystrophy       MDA MuscleWalk of Central New         $1,000.00
 Association              Jersey
 
Muscular Dystrophy       MDA MuscleWalk Central                $1,000.00
 Association              Illinois
 
Muscular Dystrophy       MDA MuscleWalk of Omaha               $1,000.00
 Association
 
Muscular Dystrophy       MDA MuscleWalk of Little Rock         $1,000.00
 Association
 
Muscular Dystrophy       MDA MuscleWalk of Baltimore           $1,000.00
 Association
 
Muscular Dystrophy       MDA MuscleWalk of Jackson             $1,000.00
 Association
 
Muscular Dystrophy       MDA MuscleWalk Spokane                $1,000.00
 Association
 
Muscular Dystrophy       MDA MuscleWalk CA                     $1,000.00
 Association
 
Muscular Dystrophy       MDA MuscleWalk of Rockford            $1,000.00
 Association
 
Muscular Dystrophy       MDA Summer Newsletter                 $1,500.00
 Association
 
Muscular Dystrophy       MDA MuscleWalk of Greater             $1,000.00
 Association              Tulsa
 
Muscular Dystrophy       MDA MuscleWalk of Chicagoland         $1,000.00
 Association              & Rockford
 
Muscular Dystrophy       MDA MuscleWalk Pittsburgh             $1,000.00
 Association
 
Muscular Dystrophy       MDA MuscleWalk of San Antonio         $1,000.00
 Association
 
Muscular Dystrophy       MDA MuscleWalk of Tampa Bay           $1,000.00
 Association
 
Muscular Dystrophy       MDA MuscleWalk Jacksonville           $1,000.00
 Association
 
Muscular Dystrophy       MDA MuscleWalk of Greater             $1,000.00
 Association              Fort Wayne
 
Muscular Dystrophy       MDA MuscleWalk Salt Lake City         $1,000.00
 Association
 
Muscular Dystrophy       MDA MuscleWalk Warwick RI             $1,000.00
 Association
 
Muscular Dystrophy       MDA MuscleWalk Portland OR            $1,000.00
 Association
 
Muscular Dystrophy       MDA MuscleWalk Eugene                 $1,000.00
 Association
 
Muscular Dystrophy       MuscleWalk: Portland                  $1,000.00
 Association
 
Muscular Dystrophy       MDA MuscleWalk of St. Louis           $1,000.00
 Association
 
Muscular Dystrophy       MDA MuscleWalk of Greater             $1,000.00
 Association              Indianapolis
 
Muscular Dystrophy       MDA Muscle Walk of Wichita            $1,000.00
 Association
 
Muscular Dystrophy       MDA MuscleWalk of Greater             $1,000.00
 Association              Cleveland
 
Muscular Dystrophy       MDA MuscleWalk of                     $1,000.00
 Association              Springfield, MO
 
Muscular Dystrophy       MDA MuscleWalk Missoula               $1,000.00
 Association
 
Muscular Dystrophy       MDA MuscleWalk Montana                $1,000.00
 Association
 
Muscular Dystrophy       MDA MuscleWalk Twin Cities            $1,000.00
 Association
 
Muscular Dystrophy       MDA MuscleWalk Charleston             $1,000.00
 Association
 
Muscular Dystrophy       MDA MuscleWalk of Greater             $1,000.00
 Association              Milwaukee
 
Muscular Dystrophy       MDA MuscleWalk of Los Angeles         $1,000.00
 Association
 
Muscular Dystrophy       MDA MuscleWalk LA                     $1,000.00
 Association
 
Muscular Dystrophy       MDA MuscleWalk of Iowa City           $1,000.00
 Association
 
Muscular Dystrophy       Northeast PA Muscle Summit            $4,000.00
 Association
 
Muscular Dystrophy       MDA MuscleWalk of Waterloo            $1,000.00
 Association
 
Muscular Dystrophy       MDA MuscleWalk of Des Moines          $1,000.00
 Association
 
Muscular Dystrophy       MDA MuscleWalk of the Quad            $1,000.00
 Association              Cities
 
Muscular Dystrophy       MDA MuscleWalk of Denver              $1,000.00
 Association
 
Muscular Dystrophy       MDA MuscleWalk Western                $1,000.00
 Association              Colorado
 
Muscular Dystrophy       MDA MuscleWalk VA                     $1,000.00
 Association
 
Museum of Science        Science Teacher Sabbatical           $66,980.00
                          Program
 
Museum of Science        Stars of STEM                        $10,000.00
 
National Fabry Disease   Volunteer Match                       $1,000.00
 Foundation
 
National Fabry Disease   Philadelphia Fabry Family             $2,200.00
 Foundation               Meeting
 
National Fabry Disease   Family Assistance Program            $10,000.00
 Foundation
 
National Fabry Disease   Conference and Camp Part 2           $70,000.00
 Foundation
 
National Fabry Disease   NFDF 2016 Fabry Family               $15,000.00
 Foundation               Educational Meetings
 
National Fabry Disease   Urgent and Unmet Needs               $40,000.00
 Foundation               Program
 
National Fabry Disease   NFDF Core Program                    $50,000.00
 Foundation
 
National Fabry Disease   Fabry Conference and Camp            $50,000.00
 Foundation
 
National Fabry Disease   NFDF Core Program                    $50,000.00
 Foundation
 
National Fabry Disease   Volunteer Match                       $7,000.00
 Foundation
 
National Gaucher         Patient Assistance CARE           $1,200,000.00
 Foundation, Inc.         Program
 
National Gaucher         Patient Assistance Program          $400,000.00
 Foundation, Inc.
 
National Gaucher         Optimal Health Initiative &         $225,000.00
 Foundation, Inc.         Education/Awareness
 
National Kidney          South Bend Indiana Kidney             $2,500.00
 Foundation               Program
 
National Kidney          Nutrition Program for Chronic         $1,000.00
 Foundation               Kidney Disease, Diabetes and
                          Hypertension
 
National Kidney          Indianapolis Kidney Health            $1,500.00
 Foundation               Awareness Program
 
National Kidney          Kidney Health Awareness               $1,500.00
 Foundation               Program
 
National Kidney          Evansville Kidney Health              $1,500.00
 Foundation               Awareness Program
 
National Kidney          Kidney Health Awareness               $1,500.00
 Foundation               Program
 
National Kidney          Patient Education and                $77,000.00
 Foundation               Awareness Program
 
National Kidney          NKF Clinical Bulletin on             $95,775.00
 Foundation               Fabry Disease
 
National MPS Society     Family Support Programs              $30,000.00
 
National MPS Society     Symposium funding                     $4,000.00
 
National MPS Society     National MPS Society                 $24,000.00
                          Conferences
 
National MPS Society     National MPS Society                 $24,000.00
                          Conferences
 
National MPS Society     Congress Sponsorships                $50,000.00
 
National MPS Society     National Run--National MPS           $10,000.00
                          Society
 
National Multiple        Volunteer Match                       $4,000.00
 Sclerosis Society
 
National Multiple        National MS Society                  $15,000.00
 Sclerosis Society        Nationwide Connection
                          Programs
 
National Multiple        Everyday Matters: Living Your        $25,000.00
 Sclerosis Society        Best Life with MS
 
National Multiple        Volunteer Match                      $25,000.00
 Sclerosis Society
 
National Multiple        Information Resource Center          $25,000.00
 Sclerosis Society
 
National Multiple        North American Education             $35,000.00
 Sclerosis Society        Program
 
National Multiple        Knowledge is Power                   $35,000.00
 Sclerosis Society
 
National Multiple        Volunteer Match                       $9,000.00
 Sclerosis Society
 
National Multiple        MS Care Management Program            $5,000.00
 Sclerosis Society
 
National Multiple        Free From Falls                       $1,000.00
 Sclerosis Society
 
National Multiple        MS Service Day                        $3,000.00
 Sclerosis Society
 
National Multiple        Day at the Bay                        $3,500.00
 Sclerosis Society
 
National Multiple        MS Exercise/Wellness Program          $5,000.00
 Sclerosis Society
 
National Multiple        Scholarship Program                  $10,000.00
 Sclerosis Society
 
National Multiple        41st annual Dinner of                 $2,500.00
 Sclerosis Society        Champions
 
National Multiple        Bike MS: I Ride with MS               $5,000.00
 Sclerosis Society        Greater NW
 
National Multiple        Bike MS Cape Cod Getaway             $50,000.00
 Sclerosis Society
 
National Multiple        National MS Society E-               $75,000.00
 Sclerosis Society        Communications Program
 
National Multiple        Muckfest MS Boston                   $25,000.00
 Sclerosis Society
 
National Multiple        Dinner of Champions Seattle          $10,000.00
 Sclerosis Society
 
National Multiple        Bike MS Ride the Vineyard            $10,000.00
 Sclerosis Society
 
National Multiple        Walk MS Walks MT                      $5,000.00
 Sclerosis Society
 
National Multiple        Walk MS Southern California &        $25,000.00
 Sclerosis Society        Nevada
 
National Multiple        MS Walks Pacific                     $10,000.00
 Sclerosis Society
 
National Multiple        Walk MS Boston                       $25,000.00
 Sclerosis Society
 
National Multiple        Fast Forward Research                $75,000.00
 Sclerosis Society        Showcase Meeting
 
National Multiple        Bike MS ``I Ride With MS'' NY       $350,000.00
 Sclerosis Society
 
National Multiple        Walk MS Phoenix                       $5,000.00
 Sclerosis Society
 
National Multiple        National MS Society Tykeson          $10,000.00
 Sclerosis Society        Fellows Conference
 
National Multiple        National MS Society                  $50,000.00
 Sclerosis Society        Leadership Conference
 
National Multiple        Bike MS Coastal Challenge Los        $10,000.00
 Sclerosis Society        Angeles
 
National Multiple        Dinner of Champions Las Vegas         $2,500.00
 Sclerosis Society
 
National Multiple        Are You What You Eat?:                $5,000.00
 Sclerosis Society        Studying Diet and
                          Supplements in Multiple
                          Sclerosis
 
National Multiple        National MS Society                  $15,000.00
 Sclerosis Society        Leadership Conference
 
National Multiple        Live Fully, LiveWell:                $15,000.00
 Sclerosis Society        Discover Your Personal Path
                          to Living Your Best Life
                          with MS
 
National Multiple        Chicago Symposium                     $5,000.00
 Sclerosis Society
 
National Multiple        MS Walks Greater Houston Area        $10,000.00
 Sclerosis Society
 
National Multiple        Moving Forward: Annual                $5,000.00
 Sclerosis Society        Meeting and Resource Fair
 
National Multiple        Bike MS NYC                           $6,000.00
 Sclerosis Society
 
National Multiple        Dallas On The Move Luncheon           $5,000.00
 Sclerosis Society
 
National Multiple        MuckFest MS                           $3,000.00
 Sclerosis Society
 
National Multiple        Gala MS                               $2,500.00
 Sclerosis Society
 
National Multiple        Bike MS: City to Shore Ride           $5,000.00
 Sclerosis Society
 
National Multiple        Crystal Boots & Silver Spurs          $2,400.00
 Sclerosis Society
 
National Multiple        Bike MS--Northern California          $5,000.00
 Sclerosis Society
 
National Multiple        MS Auction Hawaii                     $3,500.00
 Sclerosis Society
 
National Multiple        Orange Country MS Research            $2,500.00
 Sclerosis Society        Symposium
 
National Multiple        MS Walks Central Texas                $2,500.00
 Sclerosis Society
 
National Multiple        Ambassadors Ball                     $25,000.00
 Sclerosis Society
 
National Multiple        Weekend Escape VA                     $5,000.00
 Sclerosis Society
 
National Multiple        Cooling Shirts Gel Packs              $4,500.00
 Sclerosis Society
 
National Multiple        Bike MS Willamette Valley             $5,000.00
 Sclerosis Society
 
National Multiple        Smarty Pants Trivia Night             $2,500.00
 Sclerosis Society
 
National Multiple        Spellbound on the Farm                $1,500.00
 Sclerosis Society
 
National Multiple        Bike MS                               $5,000.00
 Sclerosis Society
 
National Multiple        MS On the Move Luncheon               $2,500.00
 Sclerosis Society
 
National Multiple        Women Against MS (WAMS)               $5,000.00
 Sclerosis Society        Luncheon PA
 
National Multiple        Walk MS Jones Beach                   $5,000.00
 Sclerosis Society
 
National Multiple        On The Move Luncheon New              $5,000.00
 Sclerosis Society        Orleans
 
National Multiple        Women on the Move Luncheon            $6,000.00
 Sclerosis Society
 
National Multiple        Walk MS PA                            $5,000.00
 Sclerosis Society
 
National Multiple        Women on the Move Program             $2,500.00
 Sclerosis Society
 
National Multiple        Walk MS Greater Illinois             $50,000.00
 Sclerosis Society
 
National Multiple        Walk MS Knoxville                       $750.00
 Sclerosis Society
 
National Multiple        Walk MS Michigan Chapter              $5,000.00
 Sclerosis Society
 
National Multiple        Walk MS Rochester NY                  $2,500.00
 Sclerosis Society
 
National Multiple        Walk MS Denver                       $20,000.00
 Sclerosis Society
 
National Multiple        MS Walks Minnesota, Dakotas          $15,500.00
 Sclerosis Society
 
National Multiple        Women on the Move Luncheon MO         $5,000.00
 Sclerosis Society
 
National Multiple        Walk MS Clarksville                     $750.00
 Sclerosis Society
 
National Multiple        MS Walk Indiana                      $12,000.00
 Sclerosis Society
 
National Multiple        MS Walks Iowa                         $2,500.00
 Sclerosis Society
 
National Multiple        Walk MS Wisconsin                    $10,000.00
 Sclerosis Society
 
National Multiple        20th Anniversary: Books for a        $20,000.00
 Sclerosis Society        Better Life Awards
 
National Multiple        MS Walks PA                          $10,000.00
 Sclerosis Society
 
National Multiple        Walk MS Chattanooga                     $750.00
 Sclerosis Society
 
National Multiple        Walk MS NJ                           $10,000.00
 Sclerosis Society
 
National Multiple        Walk MS MO                            $5,000.00
 Sclerosis Society
 
National Multiple        Walk MS Northern California          $25,000.00
 Sclerosis Society
 
National Multiple        MS Walks Utah & Southern             $20,000.00
 Sclerosis Society        Idaho
 
National Multiple        Walk MS CT                            $2,500.00
 Sclerosis Society
 
National Multiple        Walk MS OR                           $10,000.00
 Sclerosis Society
 
National Multiple        Walk MS Middle Tennessee                $750.00
 Sclerosis Society
 
National Multiple        Walk MS Kentucky                     $10,000.00
 Sclerosis Society
 
National Multiple        Walk MS NY                          $100,000.00
 Sclerosis Society
 
National Multiple        Walk MS OH                            $5,000.00
 Sclerosis Society
 
National Multiple        Walk MS Jacksonville                  $7,500.00
 Sclerosis Society
 
National Multiple        Walk MS Arkansas                      $3,000.00
 Sclerosis Society
 
National Multiple        Walk MS New Mexico                    $2,500.00
 Sclerosis Society
 
National Multiple        Walk MS Oklahoma                     $10,000.00
 Sclerosis Society
 
National Multiple        Walk MS Washington DC                $10,000.00
 Sclerosis Society
 
National Multiple        Walk MS Cincinnati                   $10,000.00
 Sclerosis Society
 
National Multiple        Walk MS Memphis                         $750.00
 Sclerosis Society
 
National Multiple        Walk MS Louisiana                     $5,000.00
 Sclerosis Society
 
National Multiple        Walk MS San Diego                    $20,000.00
 Sclerosis Society
 
National Multiple        Women on the Move Louisville          $1,000.00
 Sclerosis Society
 
National Multiple        On The Move Luncheon--Houston         $5,000.00
 Sclerosis Society
 
National Multiple        Walk MS Atlanta                       $5,000.00
 Sclerosis Society
 
National Multiple        Walk MS San Antonio                  $10,000.00
 Sclerosis Society
 
National Multiple        On the Move Luncheon                  $3,000.00
 Sclerosis Society
 
National Multiple        Runway for MS--Fashion Show           $2,500.00
 Sclerosis Society        Luncheon
 
National Multiple        Michigan Chapter's Annual             $2,500.00
 Sclerosis Society        Meeting & Recognition
                          Breakfast
 
National Multiple        MS Walks Arizona                     $24,000.00
 Sclerosis Society
 
National Multiple        Walk MS Alabama Mississippi           $7,500.00
 Sclerosis Society
 
National Multiple        On The Move Luncheon--Baton           $2,500.00
 Sclerosis Society        Rouge
 
National Multiple        Walk MS Ft. Lauderdale               $15,000.00
 Sclerosis Society
 
National Multiple        Women Against MS Luncheon TN          $2,500.00
 Sclerosis Society
 
National Multiple        Health Issues in Multiple             $9,000.00
 Sclerosis Society        Sclerosis Hawaii
 
National Multiple        6th Annual Festival Hispano           $4,000.00
 Sclerosis Society
 
National Multiple        MS Gala Luncheon                      $5,000.00
 Sclerosis Society
 
National Multiple        New Jersey Metro Chapter             $10,000.00
 Sclerosis Society        Volunteer Program
 
National Multiple        Annual Meeting and Education          $8,500.00
 Sclerosis Society        Conferences
 
National Multiple        MuckFest MS Houston                   $2,500.00
 Sclerosis Society
 
National Multiple        Women Against MS Luncheon             $3,000.00
 Sclerosis Society        (WAMS)
 
National Multiple        Fall Crush Nashville                  $2,500.00
 Sclerosis Society
 
National Multiple        Walk MS Houston                      $20,000.00
 Sclerosis Society
 
National Multiple        FallCrush Nashville                   $2,500.00
 Sclerosis Society
 
National Multiple        Symposium Educational                 $7,500.00
 Sclerosis Society        Programs
 
National Multiple        MuckFest MS                           $5,000.00
 Sclerosis Society
 
National Multiple        Team Finish MS at the                 $3,000.00
 Sclerosis Society        Hartford Marathon
 
National Multiple        Bike MS Louisiana                     $5,000.00
 Sclerosis Society
 
National Multiple        Bike MS: City to Shore Ride           $5,000.00
 Sclerosis Society        PA
 
National Multiple        San Antonio Bike MS                  $10,000.00
 Sclerosis Society
 
National Multiple        New Hampshire Living Well             $1,500.00
 Sclerosis Society        with MS Conference
 
National Multiple        Chapter Annual Meeting and            $5,000.00
 Sclerosis Society        Education Program:
                          Contemporary Issues in MS
 
National Multiple        Moving Mountains for MS--            $10,000.00
 Sclerosis Society        Family Weekend Retreat
 
National Multiple        Relationship Matters                  $5,000.00
 Sclerosis Society
 
National Multiple        MOVING FORWARD                        $1,500.00
 Sclerosis Society
 
National Multiple        Men with MS Elevation                $10,000.00
 Sclerosis Society        Conference
 
National Multiple        Children's Hope for                   $3,800.00
 Sclerosis Society        Understanding Multiple
                          Sclerosis
 
National Multiple        MS Research Nights                    $5,000.00
 Sclerosis Society
 
National Multiple        Day of Discovery                      $7,500.00
 Sclerosis Society
 
National Niemann-Pick    Volunteer Match                       $1,000.00
 Disease Foundation
 
National Niemann-Pick    Staying Strong as we                 $50,000.00
 Disease Foundation       Persevere in our Quest for a
                          Cure
 
National Organization    Volunteer Match                       $9,000.00
 for Rare Disorders,
 Inc.
 
National Organization    Volunteer Match                       $6,000.00
 for Rare Disorders,
 Inc.
 
National Organization    Running For Rare                      $5,000.00
 for Rare Disorders,
 Inc.
 
National Organization    NORD's Rare Diseases and             $50,000.00
 for Rare Disorders,      Orphan Products Breakthrough
 Inc.                     Summit
 
National Organization    Rare Impact Awards                   $50,000.00
 for Rare Disorders,
 Inc.
 
National Tay-Sachs &     Raising Awareness of                  $1,100.00
 Allied Diseases          Ashkenazi Jewish Genetic
 Association, Inc.        Diseases
 
National Tay-Sachs &     Expand Family Support Through         $5,000.00
 Allied Diseases          Technology
 Association, Inc.
 
National Tay-Sachs &     Imagine & Believe                    $10,000.00
 Allied Diseases
 Association, Inc.
 
National Tay-Sachs &     38th Annual Family Conference         $5,000.00
 Allied Diseases
 Association, Inc.
 
NCCN Foundation          NCCN Guidelines for Patients:        $25,000.00
                          Thyroid Cancer
 
NEHI                     The Nick Littlefield Health          $25,000.00
                          Policy Fellowship
 
NEHI                     Innovators in Health Awards          $25,000.00
 
Nephcure Foundation      11th International Podocyte           $3,000.00
                          Conference
 
Neurologic Disease       21st Fall MS Seminar--                $5,995.00
 Foundation               Optimizing Management of MS
 
Neuropathy Action        General Patient Advocacy and          $2,500.00
 Foundation               Organizational Support
 
Next Step Fund Inc.      FaceForward Campference and          $10,000.00
                          general operating support
 
North American Vascular  19th International Vascular          $10,000.00
 Biology Organization     Biology Meeting
 Inc.
 
North Shore Community    Volunteer Match                       $1,000.00
 Health Inc.
 
Northeast Business       Congress Sponsorships                 $5,000.00
 group on Health
 
Northeastern University  Allston Brighton College              $2,000.00
                          Scholarship
 
Northwest Animal Rights  Volunteer Match                       $1,000.00
 Network
 
Northwest Animal Rights  Volunteer Match                       $1,000.00
 Network
 
Norton Healthcare        Moonlight & Moonshine Gala            $5,000.00
 Foundation, Inc.
 
Norton Healthcare        Neuroscience Expo                    $10,000.00
 Foundation, Inc.
 
Norton Healthcare        1-N-3 Gala                            $5,000.00
 Foundation, Inc.
 
Operation Warm Inc.      Boston Warmth in Winter              $18,000.00
 
OptumHealth Education    Congress Sponsorships                 $7,500.00
 
Oregon Health & Science  On the Horizon: Updates in            $9,930.00
 University Foundation    Multiple Sclerosis
 
Pan Massachusetts        Volunteer Match                      $11,000.00
 Challenge
 
Pan Massachusetts        Volunteer Match                      $11,000.00
 Challenge
 
Patient Access Network   Patient Assistance Program          $100,000.00
 Foundation               for Thyroid Cancer
 
Patient Access Network   Patient Assistance Program          $100,000.00
 Foundation               for Thyroid Cancer
 
Patient Access Network   Patient Assistance Fund for         $100,000.00
 Foundation               Thyroid Cancer
 
Patient Access Network   Patient Assistance Program           $50,000.00
 Foundation               for Thyroid Cancer
 
Patient Access Network   Patient Assistance Program           $50,000.00
 Foundation               for Homozygous Familial
                          Hypercholesterolemia
 
Patient Access Network   Patient Assistance Program          $125,000.00
 Foundation               for Homozygous Familial
                          Hypercholesterolemia
 
Patient Services Inc.    Patient Assistance Program        $4,440,000.00
                          for Fabry, Pompe, MPS1, and
                          Gaucher Disease
 
Patient Services Inc.    Patient Assistance Program        $2,000,000.00
 
Patient Services Inc.    Patient Assistance Program        $6,500,000.00
 
Peer Health Exchange     Peer Health Exchange:                 $5,000.00
 Inc.                     Empowering Boston Youth to
                          Make Healthy Decisions
 
Perkins School for the   Perkins eLearning: Enhancing         $20,000.00
 Blind                    Accessible Science Education
 
Phillips Brooks House    Community Program                     $5,000.00
 Association
 Incorporated
 
Phoenix Children's       MPS patient meeting                   $1,200.00
 Hospital Foundation
 
Portland VA Research     PDX Patient Workshops                 $3,150.00
 Foundation Inc.
 
President and Fellows    Community Program                    $20,000.00
 of Harvard College
 
President and Fellows    Patient Assistance Program           $50,000.00
 of Harvard College
 
Pro Player Foundation    Flavors of Austin                     $5,000.00
 
Pro Player Foundation    Flavors of Austin                     $5,000.00
 
Project Eden Inc.        Volunteer Match                       $1,000.00
 
Project Just Because,    211 Domestic Abuse/Emergency         $10,000.00
 Inc.                     Program & Keep A Family Warm
                          Program
 
Race to Erase MS         Race to Erase MS--MS Forum           $10,000.00
 
Race to Erase MS         23rd Annual Race to Erase MS         $50,000.00
 
Read to a Child, Inc.    Community Program                     $5,000.00
 
Read to a Child, Inc.    Community Program                     $2,500.00
 
Resolve Community        Volunteer Match                       $1,000.00
 Counseling Center,
 Inc.
 
Restore                  Volunteer Match                       $1,000.00
 
Rocky Mountain Multiple  KADEP (King Adult Day                 $5,000.00
 Sclerosis Center         Enrichment Program) Annual
                          Winter Community Gathering
 
Rocky Mountain Multiple  Rocky Mountain MS Center             $10,000.00
 Sclerosis Center         Annual Gala
 
Rocky Mountain Multiple  MS4MS Event                           $5,000.00
 Sclerosis Center
 
Rocky Mountain Multiple  KADEP Annual Holiday                  $5,000.00
 Sclerosis Center         Celebration
 
Rocky Mountain Multiple  Webinar Series                        $5,000.00
 Sclerosis Center
 
Room to Grow             Community Program                     $5,000.00
 
Runkle School Extended   Volunteer Match                       $1,000.00
 Day Program Inc.
 
S S Cosmas & Damian      Community Program                     $2,500.00
 Society Inc.
 
Saint Francis Hospital   International Symposium: The         $50,000.00
 and Medical Center       Multiple Sclerosis Brain--
 Foundation               Bridging the Gap
 
Salute the Ribbon        Meet, Greet n' Eat Luncheon           $1,000.00
 Incorporated             ``Opening Doors for Health
                          Care Access to Cancer Care''
 
Samaritans Inc.          Community Program                    $25,000.00
 
Science Club For Girls   Community Program                    $10,000.00
 Inc.
 
Science Club For Girls   Catalyst Awards                      $10,000.00
 Inc.
 
Science From Scientists  STEM enrichment program for          $25,000.00
 Inc.                     Boston Public Schools
 
Science From Scientists  In-School Module-Based (ISMB)        $20,000.00
 Inc.                     STEM enrichment program
 
Science From Scientists  70th Annual Boston Citywide          $10,000.00
 Inc.                     Science Fair
 
Sharp Rees-Stealy        Congress Sponsorships                 $5,000.00
 Medical Group Sharp
 Healthcare
 
Society for Inherited    North American Metabolic             $20,000.00
 Metabolic Disorders      Academy
 
Society of Nuclear       SNMMI Patient Education Day           $5,000.00
 Medicine and Molecular
 Imaging
 
Special Olympics         Bio-Ball                              $2,500.00
 Massachusetts Inc.
 
St. Francis House        Community Program                    $10,000.00
 
Stop Hunger Now, Inc.    Volunteer Match                       $2,944.08
 
Strongwater Farm         Riding group for individuals          $7,500.00
 Therapeutic Equestrian   living with MS
 Center
 
Temple Beth Sholom [The  Patient Education and                 $6,200.00
 Tribe]                   Awareness Program
 
Temple University        Allston Brighton College              $2,000.00
                          Scholarship
 
The Boston Home, Inc.    Volunteer Match                       $1,000.00
 
The Boston Home, Inc.    The Boston Home iPad InstaAid        $12,000.00
                          Program Expansion
 
The Boston Home, Inc.    The Boston Home Arts Program         $10,000.00
 
The Boston Home, Inc.    The Boston Home B.Fit                $18,000.00
                          Wellness Program
 
The Boston Home, Inc.    The Boston Home Resident             $10,000.00
                          Family Picnic
 
The Boston Home, Inc.    Finding Your Voice                    $5,000.00
 
The Community Art        Teen Media Program                   $15,000.00
 Center
 
The Discovery Museums    Genzyme Discovery Science            $15,000.00
 
The Discovery Museums    Discovery Science Program            $15,000.00
 
The Forsyth Institute    Community Program                    $10,000.00
 
The Greater Boston Food  Volunteer Match                       $2,000.00
 Bank Inc.
 
The Greater Boston Food  General Operating Support            $10,000.00
 Bank Inc.
 
The Greater Boston Food  Volunteer Match                       $1,000.00
 Bank Inc.
 
The Jewish Community     Our Heritage and Our Health--         $1,250.00
 Center of Greater        Ashkenazi Jewish Genetic
 Kansas City              Disease and the Founder
                          Effect
 
The Jewish P.O.C.E.T.    Greater Chicago Jewish                $3,240.00
                          Festival
 
The Leukemia & Lymphoma  Light The Night Walk                  $6,500.00
 Society Inc.
 
The Life Sciences        Leadership Mid-Term Funding          $50,000.00
 Foundation               for Educational Programs
 
The McCourt Foundation   Tour de South Shore                  $10,000.00
 
The McCourt Foundation   McCourt Gala                         $20,000.00
 
The McCourt Foundation   McCourt Foundation MS                $20,000.00
                          Educational Update
 
The Oak Clinic           Oak Clinic Acorn Run                  $3,500.00
 
The Oak Clinic           Diamond Run                           $5,000.00
 
The Posse Foundation     Community Program                    $25,000.00
 
The Possible Project     The Possible Project's               $10,000.00
                          Powering Possibilities
                          Annual Gala
 
The Salvation Army       Volunteer Match                       $2,000.00
 
Thompson Island Outward  Community Program                    $10,000.00
 Bound Education Center
 Inc.
 
Thompson Island Outward  Islands Expedition Gala               $5,000.00
 Bound Education Center
 Inc.
 
Thompson Island Outward  Thompson Island 4K Trail Run          $5,000.00
 Bound Education Center
 Inc.
 
ThyCa: Thyroid Cancer    Patient Education and                $15,000.00
 Survivors'               Awareness Program
 Association, Inc.
 
ThyCa: Thyroid Cancer    19th International Thyroid           $35,000.00
 Survivors'               Cancer Survivors' Conference
 Association, Inc.
 
Tisch Multiple           Tisch MS Research Center             $15,000.00
 Sclerosis Research       Newsletter
 Center of New York,
 Inc.
 
Tisch Multiple           Future Without MS Gala                $5,000.00
 Sclerosis Research
 Center of New York,
 Inc.
 
Tisch Multiple           Future Without MS Gala               $15,000.00
 Sclerosis Research
 Center of New York,
 Inc.
 
Tisch Multiple           Tisch MS Research Center 19th        $25,000.00
 Sclerosis Research       Annual MS Patient Symposium
 Center of New York,
 Inc.
 
Triangle, Inc.           Volunteer Match                       $1,000.00
 
Triangle, Inc.           Triangle's 45th Annual Spring         $5,000.00
                          Gala
 
Tri-State Multiple       Evansville Autumn Walk                $2,500.00
 Sclerosis Association
 
Tri-State Multiple       Owensboro Autumn Walk                 $2,500.00
 Sclerosis Association
 
Tri-State Multiple       Evening of Excellence                 $2,000.00
 Sclerosis Association
 
Tri-State Multiple       Tri-State Multiple Sclerosis          $4,500.00
 Sclerosis Association    Association Autumn Walks
 
Tutoring Plus of         STEAM Enrichment Programs             $7,500.00
 Cambridge, Inc.
 
Tutoring Plus of         Community Program                     $5,000.00
 Cambridge, Inc.
 
U C San Diego            UCSD Regional MS Expositions         $50,000.00
 Foundation
 
United Network for       Congress Sponsorship                  $7,800.00
 Organ Sharing
 
United Pompe Foundation  Duke Late Onset Pompe Patient        $19,000.00
                          Meeting
 
United Pompe Foundation  Pompe Patient Meeting                $19,000.00
 
United Pompe Foundation  General Operating Support            $50,000.00
 
United Rheumatology      Congress Sponsorship                 $60,000.00
 
United Way of Tri        Volunteer Match                       $1,000.00
 County Inc.
 
United Way of Tri        Volunteer Match                       $1,000.00
 County Inc.
 
United Way of Tri        Volunteer Match                       $1,000.00
 County Inc.
 
United Way of Tri        Volunteer Match                       $2,000.00
 County Inc.
 
University of            Student Success Program,            $200,000.00
 Massachusetts            UMass Boston, College of
 Foundation Inc.          Science and Mathematics
 
University of            Massachusetts STEM Summit             $5,000.00
 Massachusetts
 Foundation Inc.
 
University of Southern   Allston Brighton College              $4,000.00
 California               Scholarship
 
Visiting Nurse           Heroes in Health Care Gala           $10,000.00
 Association of Boston
 & Affiliates
 
VNA Care Hospice Inc.    Community Program                     $5,000.00
 
VNA Care Hospice Inc.    Community Program                     $5,000.00
 
Wentworth Institute of   Allston Brighton College              $2,000.00
 Technology               Scholarship
 
West End House Boys and  Volunteer Match                       $1,000.00
 Girls Club
 
West End House Boys and  Community Program                    $25,000.00
 Girls Club
 
West End House Boys and  Community Program                    $25,000.00
 Girls Club
 
WGBH                     Pledge Night Sponsorship             $12,000.00
 
Whitehead Institute for  Whitehead Institute's CampBio        $10,000.00
 Biomedical Research      Program
 
Women's Lunch Place      Meals Program                        $35,000.00
 
Women's Lunch Place      General Operating Support            $10,000.00
 
Women's Lunch Place      Community Program                    $10,000.00
 
World Unity Inc.         Volunteer Match                       $1,000.00
 
WriteBoston              Community Program                    $10,000.00
 
Wylder Nation            Patient Education and                $15,000.00
 Foundation               Awareness Program
 
Wylder Nation            3rd Annual Living Like a             $15,000.00
 Foundation               Warrior Gala
 
YMCA of Greater Boston   Oak Square YMCA--Summer Day          $15,000.00
                          Camp Scholarships
 
ziMS Foundation          ziMS STRIKE DOWN MS Event             $5,000.00
 


                  Sponsorships and Charitable Donations
                       1st Jan 2017-31st Dec 2017
    Sanofi US and its affiliate Genzyme Corporation are committed to
   supporting sponsorships for specific activities and initiatives of
    healthcare organizations and institutions, independent medical or
professional societies, trade organizations and organized patient groups
  to improve patient care and provide information to the medical and/or
  patient communities. The goal of our charitable giving approach is to
 fund general operational support for patient/disease organizations, or
program support for community-based organizations. Sanofi US and Genzyme
    Corporation are part of the Sanofi Group, a global pharmaceutical
                                company.
 Applicant names are provided by the requestor. If applicants apply as a
  group for a single activity; all applicants may be not be identified
 above. ``Funding Amount'' is the amount that the Company funded during
  2017 identified above. ``Funding Amount'' does not include funds that
   may have been provided by other affiliated Sanofi Company Entities
                         (e.g., Sanofi Pasteur).
 
   Recipient Name(s)             Activity Title          Funding Amount
 
American Academy of      Congress Sponsorship                 $35,317.50
 Neurology
 
Academy of Managed Care  Congress Sponsorship                  $1,000.00
 Pharmacy A New Jersey
 Nonprofit Corporation
 
Academy of Managed Care  Congress Sponsorship                 $26,500.00
 Pharmacy A New Jersey
 Nonprofit Corporation
 
Accelerated Cure         2017 Leadership Summit               $15,000.00
 Project
 
Acid Maltase Deficiency  Annual Fundraiser                     $3,000.00
 Association Inc.
 
Acid Maltase Deficiency  General Operating Support            $50,000.00
 Association, Inc.
 
Alabama Kidney           Patient Education Conferences         $2,500.00
 Foundation
 
Allergy & Asthma         Understanding Atopic                 $75,000.00
 Network Mothers of       Dermatitis Guide
 Asthmatics, Inc.
 
Allergy & Asthma         Patient Activation                  $200,000.00
 Network Mothers of       Measurement Study
 Asthmatics, Inc.
 
Allergy & Asthma         GlobalSkin Conference                 $3,000.00
 Network Mothers of
 Asthmatics, Inc.
 
Allergy & Asthma         Severe Asthma Awareness             $150,000.00
 Network Mothers of       Campaign
 Asthmatics, Inc.
 
Allergy & Asthma         Project Access Initiative            $25,000.00
 Network Mothers of
 Asthmatics, Inc.
 
Allergy & Asthma         Allergy & Asthma Awareness           $25,000.00
 Network Mothers of       Day
 Asthmatics, Inc.
 
Allergy & Asthma         Allergy & Asthma Network             $25,000.00
 Network Mothers of       Corporate Council 2017
 Asthmatics, Inc.
 
Alliance for Patient     2018 Membership                     $100,000.00
 Access
 
Allston Village Main     Taste of Allston Event                $1,000.00
 Streets, Inc.
 
American Academy of      Patient AccessDerm Program          $250,000.00
 Dermatology
 
American Academy of      President's Summit on                 $5,000.00
 Dermatology              Diversity in Dermatology
 
American Academy of      Congress Sponsorship                 $17,800.00
 Neurology
 
American Academy of      Congress Sponsorship                $432,935.00
 Neurology
 
American Academy of      Emerging Leaders Program             $20,000.00
 Neurology Institute
 
American Academy of      Women Leading in Neurology           $20,000.00
 Neurology Institute      Program
 
American Academy of      Clinical Research Training           $50,000.00
 Neurology Institute      Scholarship in Multiple
                          Sclerosis
 
American Academy of      Palatucci Advocacy Leadership        $50,000.00
 Neurology Institute      Forum
 
American Academy of      Residents Scholarship Fund           $20,000.00
 Neurology Institute
 
American Academy of      Fellows Scholarship Fund             $20,000.00
 Neurology Institute
 
American Academy of      Brain Health Fair                    $10,000.00
 Neurology Institute
 
American Academy of      Neurology Annual Meeting 2017       $208,632.90
 Neurology Institute
 
American Academy of      Transforming Leaders Program         $20,000.00
 Neurology Institute
 
American Association     AAAS 2017 Annual Meeting--           $25,000.00
 For The Advancement of   Family Science Days
 Science
 
American Association of  Congress Sponsorship                  $4,300.00
 Clinical
 Endocrinologists
 
American Association of  Congress Sponsorship                 $18,500.00
 Endocrine Surgeons
 
American Association of  Congress Sponsorship                 $67,600.00
 Neuromuscular &
 Electrodiagnostic
 Medicine
 
American Brain           Membership                           $20,000.00
 Coalition
 
American Cancer Society  25th Making Strides Against           $1,000.00
                          Breast Cancer Walk
 
American Cancer Society  Bicycles Battling Cancer 2017        $11,000.00
 
American Cancer Society  Bicycles Battling Cancer 2016        $11,000.00
 
American Cancer Society  10th Annual ACS CAN New              $10,000.00
 Cancer Action Network    England Research Breakfast
 
American College of      Shared Decision Making              $125,000.00
 Allergy, Asthma &        Toolkit for Severe Atopic
 Immunology               Dermatitis
 
American College of      Severe Pediatric Asthma              $60,000.00
 Allergy, Asthma &        Shared Decision Making
 Immunology               Toolkit
 
American College of      Shared Decision Making              $125,000.00
 Allergy, Asthma &        Toolkit for Severe Pediatric
 Immunology               Asthma
 
American College of      Practice Management Center          $240,000.00
 Allergy, Asthma &
 Immunology
 
American College of      Patient Education Brochure           $31,000.00
 Allergy, Asthma &
 Immunology
 
American College of      Atopic Dermatitis Yardstick         $145,000.00
 Allergy, Asthma &        Educational Manuscript
 Immunology
 
American College of      Membership                           $60,000.00
 Chest Physicians
 
American College of      Congress Sponsorship                  $2,000.00
 Rheumatology
 
American Lung            Membership                           $20,000.00
 Association
 
American Lung            Asthma Care Coverage Project         $75,000.00
 Association
 
American Optometric      Congress Sponsorship                  $3,150.00
 Association
 
American Red Cross of    Women Who Care Leadership             $5,000.00
 Massachusetts            Breakfast
 
American Society of      ASCO Annual Meeting                 $118,000.00
 Clinical Oncology
 
American Society of      59th Annual ASH Convention          $224,300.00
 Hematology
 
American Society of      Congress Sponsorship                 $56,600.00
 Hematology
 
American Society of      Congress Sponsorship                  $3,300.00
 Human Genetics
 
American Society of      Congress Sponsorship                 $35,000.00
 Nephrology
 
American Society of      Congress Sponsorship                 $20,950.00
 Nephrology
 
American Society of      Congress Sponsorship                 $40,000.00
 Nephrology
 
American Society of      Congress Sponsorship                 $35,000.00
 Transplant Surgeons
 
American Society of      Congress Sponsorship                  $6,000.00
 Transplant Surgeons
 
American Society of      Congress Sponsorship                 $35,000.00
 Transplantation
 
American Society of      Congress Sponsorship                 $35,000.00
 Transplantation
 
American Thoracic        Corporate Membership Program         $50,000.00
 Society
 
American Thyroid         Congress Sponsorship                 $11,950.00
 Association
 
American Thyroid         Congress Sponsorship                 $18,000.00
 Association
 
American Transplant      Congress Sponsorship                 $45,000.00
 Congress
 
Americas Committee for   Congress Sponsorship                 $15,000.00
 Treatment and Research
 in Multiple Sclerosis,
 Inc.
 
ANERA (American Near     Annual Dinner                         $5,000.00
 East Refugee Aid)
 
Ann & Robert H. Lurie    MPS Patient and Family Day            $2,500.00
 Children's Hospital of
 Chicago
 
Arizona Myeloma Network  Cancer Patient & Caregivers           $3,250.00
                          Outreach & Seminar Series
 
Arthritis Foundation--   37th Annual Silver Ball Gala          $1,250.00
 St. Louis, MO
 
Arthritis Foundation--   Arthritis Industry Forum             $25,000.00
 Atlanta, GA
 
Arthritis Foundation--   Casino Night Gala                     $2,500.00
 St. Paul, MN
 
Arthritis Foundation--   Patient Engagement Program           $25,000.00
 Atlanta, GA
 
Arthritis Foundation--   Taste of the Town Gala                $5,000.00
 Hawaii Chapter
 
Arthritis Foundation--   Freedom of Movement Gala              $5,000.00
 Chicago, IL
 
Arthritis Foundation--   Houston Bone Bash Gala               $10,000.00
 Houston, TX
 
Arthritis Foundation--   PREOP Training and Engagement       $250,000.00
 Atlanta, GA              Initiative
 
Arthritis Foundation--   Walk to Cure Arthritis and          $250,000.00
 Atlanta, GA              Jingle Bell Run
 
Arthritis Foundation--   Walk to Cure Arthritis                $3,500.00
 Green Bay, WI
 
Arthritis Foundation--   Walk to Cure Arthritis                $5,000.00
 Sacramento, CA
 
Arthritis Foundation--   Walk to Cure Arthritis                $2,500.00
 Irvine, CA
 
Arthritis Foundation--   Walk to Cure Arthritis                $1,000.00
 St. Paul, MN
 
Arthritis Foundation--   Ambassador Program                  $125,000.00
 Atlanta, GA
 
Arthritis Foundation--   Advocacy Summit                      $25,000.00
 Atlanta, GA
 
Arthritis Foundation--   Walk to Cure Arthritis                $5,000.00
 Boston, MA
 
Arthritis Foundation--   Walk to Cure Arthritis                $5,000.00
 Los Angeles, CA
 
Arthritis Foundation--   Patient Voice Accumulator            $50,000.00
 Atlanta, GA              Project
 
Arthritis Foundation--   51st Annual Knowles Lecture           $7,500.00
 Northern California
 
Arthritis Foundation--   Walk to Cure Arthritis                $1,000.00
 Hawaii Chapter
 
Arthritis Foundation--   Walk to Cure Arthritis                $2,500.00
 Chicago, IL
 
Arthritis Foundation--   Walk to Cure Arthritis                $2,500.00
 New England Chapter
 
Arthritis Foundation--   Walk to Cure Arthritis                $2,500.00
 New England Chapter
 
Arthritis Foundation--   Evening of Honors Event               $5,000.00
 New Jersey Chapter
 
ASCO                     Congress Sponsorship                  $5,495.00
 
Asembia Specialty        Asembia Specialty Pharmacy           $20,000.00
 Pharmacy Summit LLC      Summit
 
Assistance Fund Inc      Patient Assistance Program       $10,000,000.00
                          for MS
 
Association For          Annual Conference                     $7,000.00
 Glycogen Storage
 Disease
 
Association of           41st Annual APHON Conference          $6,850.00
 Pediatric Hematology/
 Oncology Nurses
 
Association of VA        13th Annual AVAHO Meeting            $10,000.00
 Hematology/Oncology
 
Asthma and Allergy       Strengthening the Asthma            $200,000.00
 Foundation of America    Community
 
Asthma and Allergy       Asthma Capitals Report              $125,000.00
 Foundation of America
 
Asthma and Allergy       Supporting Patients and             $110,000.00
 Foundation of America    Families Program
 
Asthma and Allergy       Research Project                    $200,000.00
 Foundation of America
 
Asthma and Allergy       Research Project                    $120,000.00
 Foundation of America
 
Barbara Ann Karmanos     Seventh Annual Prostate               $7,500.00
 Cancer Institute         Cancer Advocacy Symposium
 
Bendcare                 National Meeting                     $10,310.00
 
Bendcare                 Educational Conferences              $92,790.00
 
Berkshire Resource       People Living with MS that            $4,000.00
 Project                  have Impaired Vision Program
 
Berkshire Resource       Functional Ability Skills for         $3,500.00
 Project                  Everyday Living With
                          Multiple Sclerosis
 
Berkshire Resource       9th Annual Gala ``Let's Kiss          $5,000.00
 Project                  MS Goodbye''
 
Berkshire Resource       Coping With The Emotional             $4,000.00
 Project                  Aspects of MS Program
 
Big Brothers Big         MySTEM Program                       $15,000.00
 Sisters of Central
 Mass Metrowest Inc.
 
Biomedical Science       Evening of Hope 2017                $100,000.00
 Careers Program
 
Biomedical Science       Hope Scholarship 2017-2018            $7,500.00
 Careers Program
 
Blue Cross Blue Shield   Blues National Summit                $15,975.00
 Association
 
Boston Business          Boston Business Journal               $5,500.00
 Journal, Inc.            Corporate Citizenship Awards
 
Boston Health Care For   Charitable Contribution--Life        $35,000.00
 The Homeless Program,    Essentials for Homeless
 Inc.                     Patients
 
Boston Partners in       Power Lunch Program                   $6,000.00
 Education, Inc.
 
Boston Private Industry  2017 Corporate Contributions         $15,000.00
 Council                  Campaign
 
Boston Private Industry  Volunteer Match                       $1,000.00
 Council
 
Bottom Line              Boston STEM Success Program          $15,000.00
 
Boys & Girls Clubs of    Fall Flashback Festival               $5,000.00
 Medford and Somerville
 Inc.
 
Boys and Girls Clubs of  Volunteer Match                       $2,000.00
 MetroWest
 
Boys and Girls Clubs of  Volunteer Match                       $1,000.00
 MetroWest
 
Boys and Girls Clubs of  Bids for Kids Auction & Gala         $10,000.00
 MetroWest
 
Boys and Girls Clubs of  Membership                           $25,000.00
 MetroWest
 
Boys and Girls Clubs of  Volunteer Match                       $2,000.00
 MetroWest
 
BPE                      Boston Teacher Residency:            $15,000.00
                          Innovative STEM Educators
                          Program
 
Breakthrough Greater     Full STEAM Ahead Program             $15,000.00
 Boston
 
Breakthrough Greater     Full STEAM Ahead Program             $10,000.00
 Boston
 
California Life          CLSA Life Sciences Academy            $8,000.00
 Sciences Association
 
California rheumatology  Annual Meeting                       $50,000.00
 Alliance
 
Cambridge Chamber of     Lead Sponsorship                      $7,500.00
 Commerce
 
Cambridge Health         Volunteer Match                       $1,000.00
 Alliance Foundation,
 Inc.
 
Cambridge School         Volunteer Match                       $1,000.00
 Volunteers, Inc.
 
Cambridgeport            2017 Summer Programs for              $5,000.00
 Neighborhood             Magazine Beach Park Support
 Association, Inc.
 
Can Do Multiple          2018 SKI for MS                      $40,000.00
 Sclerosis
 
Can Do Multiple          2017 MS Global                       $10,000.00
 Sclerosis
 
Can Do Multiple          2017 TAKE CHARGE Program             $40,000.00
 Sclerosis
 
Can Do Multiple          8th Annual Can Do Day                $10,000.00
 Sclerosis
 
Can Do Multiple          2017 CAN DO Programs                 $50,000.00
 Sclerosis
 
Can Do Multiple          Can Do On Demand Program             $60,000.00
 Sclerosis
 
Can Do Multiple          2017 TAKE CHARGE and                 $16,500.00
 Sclerosis                JUMPSTART Programs
 
Can Do Multiple          2017 JUMPSTART Programs              $80,000.00
 Sclerosis
 
Can Do Multiple          2017 Ski for MS                      $30,000.00
 Sclerosis
 
Can Do Multiple          2017 Online Programs                 $45,000.00
 Sclerosis
 
Can Do Multiple          Can Do MS eNews: Your Best            $5,000.00
 Sclerosis                Life Update
 
Case Management Society  Annual Corporate Partnership          $5,500.00
 of America
 
Case Management Society  CMSA 2017 Conference                 $14,000.00
 of America
 
Case Management Society  CMSA 27th Annual Conference &         $1,725.00
 of America               Expo
 
Case Management Society  Focus on the Future--Keeping          $1,050.00
 of New England           a Keen Eye on Tomorrow
                          Program
 
Case Management Society  Corporate Sponsorship                 $1,250.00
 of New England
 
Case Management Society  Case Management Society of            $1,000.00
 of New England           New England Conference
 
Charles River Community  Mom and Baby Program                 $15,000.00
 Health
 
CheckOrphan              Rare Disease Page Sponsorship        $40,000.00
 
Chicago Rheumatism       Congress Sponsorship                  $4,500.00
 Society
 
Childrens Gaucher        Research Grant                       $75,000.00
 Research Fund
 
Children's Hospital      Milagros para Ninos 2017 Gala         $5,000.00
 Corporation
 
Chronic Disease Fund,    Patient Assistance Program          $350,000.00
 Inc. DBA Good Days
 from CDF
 
Cincinnati Children's    Congress Sponsorship                 $10,000.00
 Hospital Medical
 Center
 
Cleveland Clinic         Congress Sponsorship                 $15,000.00
 Educational Institute
 
Cleveland Clinic         5th Annual Basic & Clinical           $3,500.00
 Educational Institute    Immunology for the Busy
                          Clinician
 
Clevleand Clinic         Scott Hamilton and Friends            $5,000.00
                          Ice Show and Gala
 
Coalition of State       CSRO State Society Key               $37,500.00
 Rheumatology             Legislator Education Program
 Organizations
 
Coalition of State       Coalition of State                  $100,000.00
 Rheumatology             Rheumatology Organizations
 Organizations            Support
 
Community Boating, Inc.  Universal Access Program 2017        $15,000.00
 
Community Farms          Fresh Food Access                    $15,000.00
 Outreach
 
Community Farms          Volunteer Match                       $1,000.00
 Outreach
 
Community Oncology       Congress Sponsorship                 $33,000.00
 Alliance
 
Community Servings,      25th Anniversary Pie in the          $10,000.00
 Inc.                     Sky Fundraiser
 
Consortium of Multiple   North American Registry for         $200,000.00
 Sclerosis Centers        Care and Research in
                          Multiple Sclerosis Support
 
Consortium of Multiple   2017 CMSC Annual Meeting            $100,000.00
 Sclerosis Centers
 
Courageous Parents       Empowering parents and               $26,250.00
 Network                  caregivers of children with
                          MPS, Gaucher, Nieman-Pick
 
Cradles to Crayons       Ready for School Program             $20,000.00
                          Support
 
Cradles to Crayons       Volunteer Match                       $2,000.00
 
Cure GM1 Incorporated    TORCH Award                           $5,000.00
 
Cure Sanfilippo          TORCH Award                           $5,000.00
 Foundation
 
Cystic Fibrosis          Uncork the Cure                      $15,000.00
 Foundation
 
Cystic Fibrosis          Massachusetts CF Cycle for            $4,000.00
 Foundation               Life Fundraiser
 
DEAF, Inc.--             Deaf-Accessible Medical Case         $10,000.00
 Developmental            Management and Access to
 Evaluation and           Health Program
 Adjustment Facilities,
 Inc.
 
Department of            Congress Sponsorship                  $5,878.75
 Pediatrics, Tufts
 Medical Center
 
Dimock Community         Volunteer Match                       $1,000.00
 Foundation Inc.
 
Dimock Community         30th Anniversary Steppin' Out       $100,000.00
 Foundation Inc.          for The Dimock Center
 
DPC Education Center     Fabry Disease Education              $27,500.00
                          Program
 
Eastern Allergy          Congress Sponsorship                 $39,000.00
 Conference
 
Emerald Necklace         14th Anniversary Party in the         $6,500.00
 Conservancy, Inc.        Park
 
Emory University         JScreen Jewish Genetic              $216,089.00
                          Disease Education Initiative
 
Endocrine Society        Congress Sponsorship                 $24,500.00
 
EveryLife Foundation     2017 RareVoice Awards                $30,000.00
 for Rare Diseases
 
EveryLife Foundation     Emerging Technologies for            $15,000.00
 for Rare Diseases        Rare Diseases: Clinical &
                          Regulatory Case Studies and
                          Approval Pathways
 
EveryLife Foundation     Rare on the Road Leadership          $30,000.00
 for Rare Diseases        Tour
 
EveryLife Foundation     TORCH Award Donations                 $5,000.00
 for Rare Diseases
 
Fabry Support &          FSIG Fun Run/Walk                     $1,500.00
 Information Group
 
Fabry Support &          General Operating Support           $100,000.00
 Information Group
 
Fabry Support &          FSIG Annual Family Conference         $1,000.00
 Information Group
 
Fabry Support &          2017 FSIG Expert Fabry               $50,000.00
 Information Group        Conference
 
Family Promise           Fundraising Event                     $2,500.00
 Metrowest, Inc.
 
Florida Society of       Congress Sponsorship                 $35,000.00
 Rheumatology
 
Food For Free            A Nutrition Program for               $5,000.00
 Committee, Inc.          Seniors and People with
                          Disabilities
 
Foundation of the        Newsletter Support                    $6,500.00
 Consortium of MS
 Centers
 
Foundation of the        Annual Meeting                        $5,450.00
 Consortium of MS
 Centers
 
Foundation of the        Research Grant                       $42,000.00
 Consortium of MS
 Centers
 
Foundation of the        Multiple Sclerosis Workforce         $32,000.00
 Consortium of MS         of the Future 2018:Medical
 Centers                  Student Research
                          Scholarships
 
Foundation of the        NARCOMS NOW Patient Quarterly        $33,583.00
 Consortium of MS         Magazine
 Centers
 
Foundation of the        Congress Sponsorship                $432,000.00
 Consortium of MS
 Centers
 
Framingham Townwide Pto  Volunteer Match                       $1,000.00
 Council
 
Franciscan Hospital For  Adaptive Sports Program              $15,000.00
 Children, Inc.
 
Friends of Children      Celebrating Fatherhood Brunch         $2,500.00
 Trust Fund, Inc.
 
Friends of Resiliency    Resiliency's Academic Support        $10,000.00
 For Life, Inc.
 
Fundacion de Esclerosis  Hurricane Relief                      $3,334.00
 Multiple de Puerto
 Rico
 
Generation Citizen,      Massachusetts Spring 2017             $6,000.00
 Inc.                     Civics Day
 
Genetic Alliance, Inc.   30th Anniversary Conference          $30,000.00
                          and Celebration
 
Genetic Alliance, Inc.   30th Anniversary Conference          $30,000.00
                          and Celebration
 
Genetic Disease          Fabry disease (dbFGP) Support       $100,000.00
 Foundation
 
Georgia Chapter of the   Georgia AAP: Pediatrics on            $5,000.00
 American Academy of      the Parkway
 Pediatrics
 
Georgia Society of       Congress Sponsorship                  $2,000.00
 Rheumatology
 
Georgia Society of       Congress Sponsorship                  $8,000.00
 Rheumatology
 
Girl Scouts of Eastern   Girls Building Self-eSTeEM           $15,000.00
 Massachusetts Inc.       Program
 
Global Academy For       Congress Sponsorship                 $55,000.00
 Medical Education,
 Inc.
 
Global Alliance for      Membership                           $50,000.00
 Patient Access
 
Global Genes             RARE Tribute to Champions of         $25,000.00
                          Hope
 
Global Genes             RARE Patient Advocacy Summit         $25,000.00
 
Global Genes             Membership                           $25,000.00
 
Greater Boston Chamber   2017 Annual Meeting                  $10,000.00
 of Commerce
 
Habitat For Humanity     High Heels and Hard Hats             $10,000.00
 Metrowest--Greater       Auction and Gala
 Worcester, Inc.
 
Habitat For Humanity     Home Renovation Build Support        $20,000.00
 Metrowest--Greater
 Worcester, Inc.
 
Hadassah Greater         Our Heritage and Our Health--           $900.00
 Detroit                  Jewish Genetic Disorders and
                          Founder Effect Program
 
Health Care For All,     Public Education Campaign            $15,000.00
 Inc.
 
Health Literacy Media    MTC Educational Program              $50,000.00
 
Hearts & Noses Hospital  Ongoing Bedside Hospital             $15,000.00
 Clown Troupe, Inc.       Clown Visits Program
 
Hematology Oncology      Congress Sponsorship                  $7,500.00
 Managers of New York,
 Inc.
 
Holy Name Health Care    2017 MS Awards Reception              $2,500.00
 MS Center
 
Holy Name Medical        20th Annual Spring Fling to           $2,500.00
 Center                   Benefit MS
 
Hope and Comfort, Inc.   Hope and Comfort Program              $5,000.00
                          Support
 
Horizons for Homeless    19th Annual Women's Breakfast         $5,000.00
 Children
 
Houston Food Bank        Volunteer Match                       $1,000.00
 
Imedex, LLC              Congress Sponsorship                 $94,778.35
 
International Institute  Healthcare Navigation for            $15,000.00
 of New England           Refugees Program
 
International Institute  2017 Golden Door Award Gala          $10,000.00
 of New England
 
International Institute  Transport Costs for Bicycles            $100.00
 of New England           for Refugee Families
 
International            20th Anniversary IOMSN Dinner        $30,000.00
 Organization of
 Multiple Sclerosis
 Nurses
 
International            2017 MS Perspectives Digital         $40,000.00
 Organization of          Magazine
 Multiple Sclerosis
 Nurses
 
International Society    5th Glycoproteinoses                 $16,650.00
 For Mannosidosis &       International Conference
 Related Disease Inc.
 
Jewish Genetic Disease   General Operating Support             $5,000.00
 Consortium
 
Knect365 US, Inc.        Battle of the Biotech Bands           $5,000.00
                          Fundraiser
 
Kometa Serbian           Volunteer Match                       $1,000.00
 Childrens Program Inc.
 
Life Science Cares,      Life Science Cares Impact            $10,000.00
 Inc.                     Breakfast
 
Light of Life            Light of Life Foundation 2017        $40,000.00
 Foundation               Activities
 
Little Brothers/Friends  Medical Escort/Transportation         $7,500.00
 of the Elderly           Program
 
Little Miss Hannah       Vegas Cares About Rare Kids           $5,000.00
 Foundation               5K
 
Little Miss Hannah       Vegas Cares About Rare Kids           $2,500.00
 Foundation               5K
 
LUGPA                    LUGPA Annual Meeting                 $10,000.00
 
Lycee International De   ISB Benefit Gala                      $8,000.00
 Boston International
 School of Boston Inc.
 
MagellanRx Management    Congress Sponsorship                  $7,500.00
 
March of Dimes           Volunteer Match                       $2,000.00
 Foundation
 
March of Dimes           Boston March for Babies              $25,000.00
 Foundation               Fundraiser
 
March of Dimes           Volunteer Match                       $1,000.00
 Foundation
 
Margaret Fuller          Youth Development Programs           $15,000.00
 Neighborhood House
 
Mass Insight Education   STEM and English Program             $15,000.00
 and Research Institute
 Inc.
 
Massachusetts Bay        STEM Mentor Program                  $40,000.00
 Community College
 Foundation
 
Massachusetts            Patient Advocacy Summit              $10,000.00
 Biotechnology Council
 
Massachusetts            Congress Sponsorship                 $25,000.00
 Biotechnology Council
 
Massachusetts            MassBio Annual Meeting               $10,000.00
 Biotechnology Council
 
Massachusetts            Rare Disease Day 2017                 $1,000.00
 Biotechnology Council
 
Massachusetts            2017 Champions for                    $3,500.00
 Biotechnology            Biotechnology Awards
 Education Foundation,
 Inc.
 
Massachusetts            BioTeach Program                     $50,000.00
 Biotechnology
 Education Foundation,
 Inc.
 
Massachusetts            Life Sciences Workforce 2017,         $3,500.00
 Biotechnology            2nd Annual Conference
 Education Foundation,
 Inc.
 
Massachusetts College    Sanofi Genzyme Biotchnology           $7,000.00
 of Pharmacy and Health   College Scholarship
 Sciences
 
Massachusetts State      Advancing Science & Health           $50,000.00
 Science and              Education Programs
 Engineering Fair, Inc.
 
Mayo Clinic              Congress Sponsorship                  $2,000.00
 
MedImpact Healthcare     Congress Sponsorship                  $8,000.00
 Systems, Inc.
 
MetroWest Chamber of     Board of Directors Luncheon             $250.00
 Commerce
 
Metrowest Free Medical   Access to Women's Health Care        $15,000.00
 Program Inc.             for the Uninsured
 
Mid America MS           Eat Bid Laugh 6 Event                $10,000.00
 Achievement Center
 
Mid America MS           Race to Nowhere 19                    $5,000.00
 Achievement Center
 
Milwaukee Synagogue for  Education Program                     $5,000.00
 Russian Jews:
 Congregation Moshiach
 Now Inc.
 
Milwaukee Synagogue for  Education Program                     $5,000.00
 Russian Jews:
 Congregation Moshiach
 Now Inc.
 
MS Bright Spots of Hope  MS Evening of Hope                    $2,500.00
 
MS Cure Fund             Patient Education Programs           $25,000.00
 
MS Cure Fund             Late Summer Education                $25,000.00
                          Programs
 
MS Cure Fund             Lifestyle Management Programs        $15,000.00
                          Spring 2017
 
MS Cure Fund             2017 Spring MS Health Fair            $1,500.00
 
MS HOPE FOR A CURE INC.  2017 MS Hope Day                     $10,000.00
 
MS Views And News Inc.   MS Neuro TV                          $35,000.00
 
MS Views And News Inc.   Living Beyond MS--Effective          $20,000.00
                          Communication with Your
                          Healthcare Team
 
MS Views And News Inc.   The Compass To Care Program          $73,550.00
 
MS Views And News Inc.   2017 Display Sponsorship             $10,000.00
                          request
 
MS Views And News Inc.   Educational Programs                 $23,825.00
 
MS Views And News Inc.   Educational Programs                 $25,000.00
 
MS Views And News Inc.   2nd Annual Champions Tackling        $10,000.00
                          MS Awards Dinner Gala
 
MS Views And News Inc.   MS Views and News 2017                $1,000.00
                          Bowlathon
 
Multiple Myeloma Cure    Defeat Multiple Myeloma run/          $5,000.00
 Seeker Society           walk
 
Multiple Sclerosis       Navigating MS: Optimizing            $73,125.00
 Association of America
 
Multiple Sclerosis       MSAA MRI Access Fund                $125,000.00
 Association of America
 
Multiple Sclerosis       MSAA Improving Lives Benefit          $2,500.00
 Association of America   2017
 
Multiple Sclerosis       Educational Programs                 $60,000.00
 Association of America
 
Multiple Sclerosis       Understanding MS Progression         $39,000.00
 Association of America
 
Multiple Sclerosis       MS Fest                              $10,000.00
 Center of Georgia
 
Multiple Sclerosis       Health, Hope & Hops                   $7,000.00
 Center of Georgia
 
Multiple Sclerosis       MS Focus' EmpowerSource              $35,000.00
 Foundation               Newsleter
 
Multiple Sclerosis       Mind & Mobility                       $5,000.00
 Foundation
 
Multiple Sclerosis       Homecare Assistance Grant            $20,000.00
 Foundation               Program
 
Multiple Sclerosis       Assistive Technology Program         $30,000.00
 Foundation
 
Multiple Sclerosis       2017 National MS Education           $30,000.00
 Foundation               and Awareness Month
 
Multiple Sclerosis       30th Anniversary Gala                 $5,000.00
 Foundation               ``Bourbon & Blues''
 
Multiple Sclerosis       2017 Mission Steps Walks & MS         $8,000.00
 Resources of Central     Awareness Days
 New York, Inc.
 
Multiple Sclerosis       MS Awareness Expo                     $1,000.00
 Society of Colorado
 Springs, Inc.
 
Muscular Dystrophy       Muscle Walk                           $1,000.00
 Association--Pittsburg
 h, PA
 
Muscular Dystrophy       Muscle Walk                           $1,000.00
 Association--Denver,
 CO
 
Muscular Dystrophy       5th Annual Muscle Summit              $6,000.00
 Association--Harrisbur
 g, PA
 
Muscular Dystrophy       MDA Muscle Summit                     $8,000.00
 Association--Broomall,
 PA
 
Muscular Dystrophy       Muscle Walk                           $1,000.00
 Association--Shrevepor
 t, LA
 
Muscular Dystrophy       Muscle Walk                           $1,000.00
 Association--Deerfield
 Beach, FL
 
Muscular Dystrophy       Muscle Walk                           $1,000.00
 Association--Tallahass
 ee, FL
 
Muscular Dystrophy       Muscle Walk                           $1,000.00
 Association--Grand
 Rapids, MI
 
Muscular Dystrophy       Muscle Walk                           $1,000.00
 Association--Fort
 Wayne, IN
 
Muscular Dystrophy       Muscle Walk                           $1,000.00
 Association--Metairie,
 LA
 
Muscular Dystrophy       Muscle Walk                           $1,000.00
 Association--Deerfield
 Beach, FL
 
Muscular Dystrophy       Muscle Walk                           $1,000.00
 Association--Los
 Angeles, CA
 
Muscular Dystrophy       Muscle Walk                           $1,000.00
 Association--Shrevepor
 t, LA
 
Muscular Dystrophy       Muscle Walk                           $1,000.00
 Association--Harrisbur
 g, PA
 
Muscular Dystrophy       Muscle Walk                           $1,000.00
 Association--Allentown
 , PA
 
Muscular Dystrophy       Muscle Walk                           $2,000.00
 Association--Urbana,
 IL
 
Muscular Dystrophy       Muscle Walk                           $1,000.00
 Association--Billings,
 MT
 
Muscular Dystrophy       Muscle Walk                           $1,000.00
 Association--San
 Diego, CA
 
Muscular Dystrophy       Muscle Walk                           $1,000.00
 Association--Cincinnat
 i, OH
 
Muscular Dystrophy       Muscle Walk                           $1,000.00
 Association--Portland,
 MA
 
Muscular Dystrophy       Muscle Walk                           $1,000.00
 Association--Spokane,
 WA
 
Muscular Dystrophy       Muscle Walk                           $1,000.00
 Association--Salt Lake
 City, UT
 
Muscular Dystrophy       Muscle Walk                           $1,000.00
 Association--Louisvill
 e, KY
 
Muscular Dystrophy       Muscle Walk                           $1,000.00
 Association--Wilmingto
 n, NC
 
Muscular Dystrophy       Muscle Walk                           $1,000.00
 Association--Worthingt
 on, OH
 
Muscular Dystrophy       Muscle Walk                           $1,000.00
 Association--Dallas,
 TX
 
Muscular Dystrophy       Muscle Walk                           $1,000.00
 Association--Albany,
 NY
 
Muscular Dystrophy       Muscle Walk                           $1,000.00
 Association--Chicago,
 IL
 
Muscular Dystrophy       Muscle Walk                           $1,000.00
 Association--Greensbor
 o, NC
 
Muscular Dystrophy       Muscle Walk                           $1,000.00
 Association--Columbus,
 OH
 
Muscular Dystrophy       Muscle Walk                           $1,000.00
 Association--Albany,
 NY
 
Muscular Dystrophy       Muscle Walk                           $1,000.00
 Association--Cincinnat
 i, OH
 
Muscular Dystrophy       Muscle Walk                           $1,000.00
 Association--Portland,
 OR
 
Muscular Dystrophy       Muscular Dystrophy Summer             $2,000.00
 Association--North       Camp Program
 Haven, CT
 
Muscular Dystrophy       Montana Muscular Dystrophy            $2,000.00
 Association--Billings,   Association Summer Camp 2017
 MT
 
Muscular Dystrophy       MDA Limb Girdle Muscular            $900,000.00
 Association--Chicago,    Dystrophy (LGMD) Genetic
 IL                       Testing Program
 
Muscular Dystrophy       2017 Summer Camp                      $2,500.00
 Association--Spokane,
 WA
 
Muscular Dystrophy       Muscle Walk                           $1,000.00
 Association--Okemos,
 MI
 
Muscular Dystrophy       2017 MDA Summer Camp of               $2,500.00
 Association--Tulsa, OK   Oklahoma
 
Muscular Dystrophy       National Education and Impact       $400,000.00
 Association - Chicago,   Partner
 IL
 
Muscular Dystrophy       MDA Summer Newsletter                 $2,000.00
 Association--Columbia,
 SC
 
Muscular Dystrophy       2017 MDA Summer Camp                  $2,500.00
 Association--Cincinnat
 i, OH
 
Muscular Dystrophy       MDA Summer Camp                       $5,000.00
 Association--Mountlake
 Terrace, WA
 
Muscular Dystrophy       MDA Summer Camp                       $5,000.00
 Association--Denver,
 CO
 
Muscular Dystrophy       2017 MDA Summer Camp                  $2,500.00
 Association--Shrevepor
 t, LA
 
Muscular Dystrophy       2017 MDA Summer Camp                  $8,000.00
 Association--Dallas,
 TX
 
Muscular Dystrophy       MDA Summer Camp                       $2,500.00
 Association--Bolingbro
 ok, IL
 
Muscular Dystrophy       Muscle Walk                           $1,000.00
 Association--Denver,
 CO
 
Muscular Dystrophy       Muscle Walk                           $1,000.00
 Association--Denver,
 CO
 
Muscular Dystrophy       Muscle Walk                           $1,000.00
 Association--North
 Haven, CT
 
Muscular Dystrophy       Muscle Walk                           $1,000.00
 Association--Maywood,
 NJ
 
Muscular Dystrophy       Muscle Walk                           $1,000.00
 Association--Indianapo
 lis, IN
 
Muscular Dystrophy       Muscle Walk                           $1,000.00
 Association--Urbana,
 IL
 
Muscular Dystrophy       Muscle Walk                           $1,000.00
 Association--Louisvill
 e, KY
 
Muscular Dystrophy       Muscle Walk                           $1,000.00
 Association--Chicago,
 IL
 
Muscular Dystrophy       Muscle Walk                           $1,000.00
 Association--Edina, MN
 
Muscular Dystrophy       Muscle Walk                           $1,000.00
 Association--Metairie,
 LA
 
Muscular Dystrophy       Muscle Walk                           $1,000.00
 Association--Reston,
 VA
 
Muscular Dystrophy       Muscle Walk                           $1,000.00
 Association--Little
 Rock, AR
 
Muscular Dystrophy       Muscle Walk                           $1,000.00
 Association--Springfie
 ld, MO
 
Muscular Dystrophy       Muscle Walk                           $1,000.00
 Association--Cedar
 Rapids, IA
 
Muscular Dystrophy       Muscle Walk                           $1,000.00
 Association--Fort
 Myers, FL
 
Muscular Dystrophy       Muscle Walk                           $1,000.00
 Association--Bolingbro
 ok, IL
 
Muscular Dystrophy       Muscle Walk                           $1,000.00
 Association--Green
 Bay, WI
 
Muscular Dystrophy       Muscle Walk                           $1,000.00
 Association--Edina, MN
 
Muscular Dystrophy       Muscle Walk                           $1,000.00
 Association--Dallas,
 TX
 
Muscular Dystrophy       Quarterly Newsletter                  $3,000.00
 Association--Westbrook
 , ME
 
Muscular Dystrophy       TORCH Award                           $5,000.00
 Association--Midland,
 TX
 
Muscular Dystrophy       Muscle Walk                           $1,000.00
 Association--St.
 Petersburg, FL
 
Muscular Dystrophy       2017 MDA Muscle Walk of               $1,000.00
 Association--Jacksonvi   Jacksonville
 lle, FL
 
Muscular Dystrophy       Muscle Walk                           $1,000.00
 Association--Charlotte
 , NC
 
Muscular Dystrophy       Muscle Walk                           $1,000.00
 Association--Towson,
 MD
 
Muscular Dystrophy       Muscle Walk                           $1,500.00
 Association--Cedar
 Rapids, IA
 
Muscular Dystrophy       Muscle Walk & Fire Truck Pull         $1,000.00
 Association--Austin,
 TX
 
Muscular Dystrophy       Muscle Walk                           $1,500.00
 Association--Sacrament
 o, CA
 
Muscular Dystrophy       Muscle Walk                           $1,000.00
 Association--Cedar
 Rapids, IA
 
Muscular Dystrophy       Muscle Walk                           $1,000.00
 Association--Fort
 Wayne, IN
 
Muscular Dystrophy       Muscle Walk                           $1,000.00
 Association--Birmingha
 m, AL
 
Muscular Dystrophy       Muscle Walk                           $1,000.00
 Association--Edina, MN
 
Muscular Dystrophy       Muscle Walk                           $1,000.00
 Association--Salt Lake
 City, UT
 
Muscular Dystrophy       Muscle Walk                           $1,000.00
 Association--Lafayette
 , LA
 
Muscular Dystrophy       Spring Newsletter                     $1,500.00
 Association--Columbia,
 SC
 
Muscular Dystrophy       Muscle Walk                           $1,000.00
 Association--Memphis,
 TN
 
Muscular Dystrophy       Muscle Walk                           $1,000.00
 Association--Allentown
 , PA
 
Muscular Dystrophy       Muscle Walk                           $1,000.00
 Association--Cedar
 Rapids, IA
 
Muscular Dystrophy       Muscle Walk                           $1,000.00
 Association--Lafayette
 , LA
 
Muscular Dystrophy       Muscle Walk                           $1,000.00
 Association--Maryland
 Heights, MO
 
Muscular Dystrophy       1st Quarter Newsletter                $1,000.00
 Association--North
 Haven, CT
 
Muscular Dystrophy       Second Quarter Newsletter             $1,500.00
 Association--Chicago,
 IL
 
Muscular Dystrophy       Muscle Walk                           $1,000.00
 Association--Cleveland
 , OH
 
Muscular Dystrophy       Muscle Walk                           $1,000.00
 Association--Oklahoma
 City, OK
 
Muscular Dystrophy       Muscle Walk                           $1,000.00
 Association--Wilmingto
 n, NC
 
Muscular Dystrophy       Muscle Walk                           $1,000.00
 Association--San
 Antonio, TX
 
Muscular Dystrophy       Muscle Walk                           $1,000.00
 Association--Scottsdal
 e, AZ
 
Muscular Dystrophy       Muscle Walk                           $1,000.00
 Association--Montgomer
 y, AL
 
Muscular Dystrophy       First Quarter Newsletter              $2,500.00
 Association--Chicago,
 IL
 
Muscular Dystrophy       4th Quarter Newsletter                $1,500.00
 Association--North
 Haven, CT
 
Muscular Dystrophy       Muscle Walk                           $1,000.00
 Association--El Paso,
 TX
 
Muscular Dystrophy       Summer Camp 2017                      $8,000.00
 Association--Cypress,
 CA
 
Muscular Dystrophy       1st Quarter Newsletter                $3,000.00
 Association--North
 Haven, CT
 
Muscular Dystrophy       Kids Art Auction                      $2,000.00
 Association--Lake
 Mary, FL
 
Muscular Dystrophy       Muscle Walk                           $2,000.00
 Association--Westborou
 gh, MA
 
Muscular Dystrophy       Muscle Walk                           $1,000.00
 Association--Westborou
 gh, MA
 
Muscular Dystrophy       Muscle Walk                           $1,000.00
 Association--Brentwood
 , TN
 
Muscular Dystrophy       Muscle Walk                           $1,000.00
 Association--Lake
 Mary, FL
 
Muscular Dystrophy       Muscle Walk                           $1,000.00
 Association--Brookfiel
 d, WI
 
Muscular Dystrophy       Muscle Walk                           $1,000.00
 Association--Wichita,
 KS
 
Muscular Dystrophy       MA and RI Newsletters                $10,000.00
 Association--Westborou
 gh, MA
 
Museum of Fine Arts      Membership                           $20,000.00
 
Museum of Science        Sanofi Genzyme Teacher               $66,980.00
                          Sabbatical Program 2017-2018
 
Museum of Science        Stars of STEM 2017                   $10,000.00
 
National Bone Marrow     Caregiver Webinar Series              $2,500.00
 Transplant Link
 
National Comprehensive   Membership                          $210,000.00
 Cancer Network
 
National Eczema          Be Well, Mind + Body, Eczema        $100,000.00
 Association              Awareness Month Campaign
 
National Eczema          NEA Educational Webcast for          $15,000.00
 Association              Patients & Caregivers
 
National Eczema          Leaders in Eczema Forum             $100,000.00
 Association              Series
 
National Eczema          Health Care Provider                 $85,000.00
 Association              Engagement Program
 
National Eczema          Patient Engagement Program          $150,000.00
 Association
 
National Eczema          Ambassadors Program                 $100,000.00
 Association
 
National Fabry Disease   Fabry Family Conference               $6,500.00
 Foundation
 
National Fabry Disease   2017 Urgent and Unmet Needs          $40,000.00
 Foundation               Program
 
National Fabry Disease   2017 Annual Educational              $50,000.00
 Foundation               Conference and Fabry Family
                          Camp
 
National Fabry Disease   Annual Conference                    $70,000.00
 Foundation
 
National Fabry Disease   2018 NFDF Core Program Grant        $100,000.00
 Foundation
 
National Fabry Disease   Fabry Family Meeting                  $3,000.00
 Foundation
 
National Fabry Disease   Family Meeting                        $5,000.00
 Foundation
 
National Fabry Disease   2017 Family Assistance               $10,000.00
 Foundation               Program
 
National Gaucher         CARE Programs                       $800,000.00
 Foundation
 
National Gaucher         Optimal Health Initiative &         $900,000.00
 Foundation               Education and Awareness
 
National Gaucher         CARE Programs                     $1,500,000.00
 Foundation
 
National Gaucher         Optimal Health Initiative &         $400,000.00
 Foundation               Education and Awareness
 
National Kidney          Kidney Walk                          $25,000.00
 Foundation
 
National Kidney          Spring Clinical Meeting               $3,500.00
 Foundation
 
National Kidney          Kidney Health Risk Assessment         $1,500.00
 Foundation of Indiana    Program
 
National Kidney          Kidney Health Risk Assessment         $1,500.00
 Foundation of Indiana    Program
 
National Kidney          Kidney Health Risk Assessment         $1,500.00
 Foundation of Indiana    Program
 
National Kidney          Kidney Health Risk Assessment         $1,500.00
 Foundation of Indiana    Program
 
National Kidney          Kidney Walk                           $1,000.00
 Foundation of Michigan
 
National Kidney          31st Annual Gift of Life Gala         $2,500.00
 Foundation of Eastern
 Missouri, Metro East
 
National MPS Society     2018 International MPS              $100,000.00
                          Symposium
 
National MPS Society     National MPS Society Gala               $134.00
                          Silent Auction
 
National MPS Society     National MPS Society Family           $7,500.00
                          Conference Scholarships
 
National MPS Society     31st Annual Family Conference        $35,000.00
 
National MPS Society     National MPS Society 2017 Run/       $20,000.00
                          Walk Program
 
National Multiple        Free From Falls                       $1,150.00
 Sclerosis Society--
 Southern California &
 Nevada Chapter
 
National Multiple        Champions on the Move                 $5,000.00
 Sclerosis Society--
 Upstate New York
 Chapter
 
National Multiple        Spellbound In the Vineyard            $2,500.00
 Sclerosis Society--
 Upstate New York
 Chapter
 
National Multiple        2016 Annual Meeting                   $2,500.00
 Sclerosis Society--
 Greater Delaware
 Valley Chapter
 
National Multiple        Women on the Move Luncheon            $2,500.00
 Sclerosis Society--
 Greater Illinois
 Chapter
 
National Multiple        Life-Changing Breakthroughs:         $65,000.00
 Sclerosis Society--      MS Society Impact Series
 Colorado-Wyoming
 Chapter
 
National Multiple        Leadership Conference 2017           $15,000.00
 Sclerosis Society--
 Colorado-Wyoming
 Chapter
 
National Multiple        The Tykeson Fellows                  $15,000.00
 Sclerosis Society--      Conference
 Colorado-Wyoming
 Chapter
 
National Multiple        Moving Mountains for MS:             $10,000.00
 Sclerosis Society--      Family Weekend Retreat
 Kentucky-Southeast
 Indiana Chapter
 
National Multiple        Crystal Boots and Silver              $3,000.00
 Sclerosis Society--      Spurs
 Kentucky-Southeast
 Indiana Chapter
 
National Multiple        Nationwide MS Navigator              $50,000.00
 Sclerosis Society--      Services
 Colorado-Wyoming
 Chapter
 
National Multiple        On the Move Luncheon                  $2,500.00
 Sclerosis Society--
 Gateway Area Chapter
 
National Multiple        Walk MS--Lanyard Sponsorship         $10,000.00
 Sclerosis Society--New
 Jersey Metro Chapter
 
National Multiple        On the Move Luncheon                  $2,500.00
 Sclerosis Society--
 South Central Chapter
 
National Multiple        Annual Meeting & Day of               $7,500.00
 Sclerosis Society--Mid   Discovery
 Florida Chapter
 
National Multiple        Volunteer Program                    $10,000.00
 Sclerosis Society--New
 Jersey Metro Chapter
 
National Multiple        Fall Crush Knoxville                  $2,500.00
 Sclerosis Society--Mid
 South Chapter
 
National Multiple        Fall Crush Knoxville                  $2,500.00
 Sclerosis Society--Mid
 South Chapter
 
National Multiple        Women Against MS Luncheon             $3,000.00
 Sclerosis Society--New
 York City Chapter
 
National Multiple        Challenge Walk MS                     $5,000.00
 Sclerosis Society--New
 York City Chapter
 
National Multiple        On the Move Baltimore                 $3,500.00
 Sclerosis Society--New
 York City Chapter
 
National Multiple         Ambassadors Ball                    $10,000.00
 Sclerosis Society--New
 York City Chapter
 
National Multiple        Hispanic Outreach Initiative         $10,000.00
 Sclerosis Society--New
 York City Chapter
 
National Multiple        MS Scholarship Program               $15,000.00
 Sclerosis Society--New
 York City Chapter
 
National Multiple        2017 Weekend Escape                   $5,000.00
 Sclerosis Society--New
 York City Chapter
 
National Multiple        2017 Dinner of Champions              $2,500.00
 Sclerosis Society--
 Reno Chapter
 
National Multiple        Everyday Matters: Living Your        $20,000.00
 Sclerosis Society--New   Best Life with MS
 York City Chapter
 
National Multiple        International Progressive MS        $122,249.00
 Sclerosis Society--New   Alliance Industry Forum
 York City Chapter
 
National Multiple        2017 On The Move Luncheon             $2,500.00
 Sclerosis Society--New
 York City Chapter
 
National Multiple        Books for a Better Life              $20,000.00
 Sclerosis Society--New   Awards
 York City Chapter
 
National Multiple        Women on the Move Luncheon            $6,000.00
 Sclerosis Society--New
 York City Chapter
 
National Multiple        National ``Living with MS''         $600,000.00
 Sclerosis Society--New   Event
 York City Chapter
 
National Multiple        Walk MS 2017                         $25,000.00
 Sclerosis Society--
 South Florida Chapter
 
National Multiple        Festival Hispano                      $1,500.00
 Sclerosis Society--
 South Florida Chapter
 
National Multiple        MS Gala Luncheon 2017                 $2,500.00
 Sclerosis Society--
 South Florida Chapter
 
National Multiple        MS Walk West Virginia                 $7,500.00
 Sclerosis Society--
 Central Virginia
 Chapter
 
National Multiple        Patient Assistance Program            $5,000.00
 Sclerosis Society--
 Indiana State Chapter
 
National Multiple        Walk MS                               $5,000.00
 Sclerosis Society--
 Long Island Chapter
 
National Multiple        Women on the Move Luncheon &          $1,250.00
 Sclerosis Society--      Fashion Show
 Ohio Valley Chapter
 
National Multiple        2017 MS Neurology Dinner              $5,000.00
 Slcerosis Society--
 Pacific South Coast
 Chapter
 
National Multiple        Challenge Walk MS                     $2,500.00
 Slcerosis Society--
 Pacific South Coast
 Chapter
 
National Niemann-Pick    Reinvention of The National          $75,000.00
 Disease Foundation       Niemann Pick Disease
                          Foundation (NNPDF)
 
National Organization    Rare Disease Day Fundraiser          $10,000.00
 for Rare Disorders
 
National Organization    2017 Rare Diseases and Orphan        $50,000.00
 for Rare Disorders,      Product Breakthrough Summit
 Inc.
 
National Organization    Running for Rare                      $5,000.00
 for Rare Disorders,
 Inc.
 
National Organization    2017 Corporate Council               $25,000.00
 for Rare Disorders,
 Inc.
 
National Organization    2017 Rare Impact Awards              $50,000.00
 for Rare Disorders,
 Inc.
 
National Organization    Undiagnosed Diseases Network          $5,000.00
 for Rare Disorders,      Fund
 Inc.
 
National Organization    Orphan Drug Act Advocacy             $75,000.00
 for Rare Disorders,
 Inc.
 
National Parkinson       Moving Day--Boston 2016               $1,000.00
 Foundation
 
National Society of      36th Annual Education                 $2,800.00
 Genetic Counselors       Conference
 
National Tay-Sachs &     Imagine & Believe                    $20,000.00
 Allied Diseases
 Association, Inc.
 
National Tay-Sachs &     Raising Awareness of                  $1,100.00
 Allied Diseases          Ashkenazi Jewish Genetic
 Association, Inc.        Diseases
 
National Tay-Sachs &     39th Annual Family Conference        $10,000.00
 Allied Diseases
 Association, Inc.
 
National Tay-Sachs &     Family Support Resource Video         $5,000.00
 Allied Diseases          Series and Podcasts
 Association, Inc.
 
NEHI                     NEHI's Innovators in Health          $25,000.00
                          Awards
 
NEHI                     The Nick Littlefield Health          $25,000.00
                          Policy Fellowship
 
Neuroscience Centers of  How to Improve Physical and           $6,640.00
 Florida Foundation,      Psychological Health Program
 Inc.
 
Neuroscience Centers of  Maintaining Intimacy with             $3,895.72
 Florida Foundation,      Multiple Sclerosis
 Inc.
 
Next Step Fund, Inc.     Summer Campference Program           $10,000.00
 
Northeastern University  Biotchnology College                  $1,000.00
                          Scholarship
 
Northern California      Congress Sponsorship                 $10,000.00
 Rheumatology Society
 
Northern New England     Congress Sponsorship                  $2,000.00
 Clinical Oncology
 Society
 
Operation Warm, Inc.     Boston Coat Program                  $20,000.00
 
Operation Warrior        Wounded Military Event                  $798.00
 Wishes
 
Pan Massachusetts        Pan Mass Challenge                   $11,000.00
 Challenge
 
Patient Access Network   Patient Assistance Program          $460,000.00
 Foundation
 
Patient Access Network   Patient Assistance Program          $200,000.00
 Foundation
 
Patient Services, Inc.   Patient Assistance Program          $481,250.00
 
Patient Services, Inc.   Patient Assistance Program        $2,902,500.00
 
Patient Services, Inc.   Patient Assistance Program          $237,500.00
 
Patient Services, Inc.   Patient Assistance Program          $818,750.00
 
Patient Services, Inc.   Patient Assistance Program          $650,000.00
 
Patient Services, Inc.   Patient Assistance Program        $5,960,000.00
 
PCMA Pharmaceutical      Congress Sponsorship                 $60,000.00
 Care Management
 Association
 
Pediatric Endocinology   Congress Sponsorship                  $6,200.00
 Nursey Society
 
Pediatric Endocrine      Congress Sponsorship                 $27,500.00
 Society
 
Peer Health Exchange,    Peer Health Exchange Program          $5,000.00
 Inc.
 
Pennsylvania             Congress Sponsorship                 $10,000.00
 Rheumatology Society
 
Perkins School for the   Enhancing Accessible Science         $20,000.00
 Blind                    and Technology Education
                          eLearning Program
 
Philadelphia Rheumatism  5th Annual Ralph Schumacher           $2,250.00
 Society                  Lecture
 
Phillips Brooks House    Bridges Workshop                      $3,000.00
 Association
 Incorporated
 
President and Fellows    The Family Van Health Clinic         $50,000.00
 of Harvard College
 
Pro Player Foundation    Flavors of Austin Fundraiser          $5,000.00
 
Project HOPE             Project Hope Gala                    $10,000.00
 
Project Just Because,    211 Domestic Abuse/Emergency         $10,000.00
 Inc.                     Program & Keep A Family Warm
                          Program
 
Prostate Cancer Academy  Proscate Cancer Academy 2017          $7,500.00
 
Race to Erase MS         24th Annual Race to Erase MS         $15,000.00
 
Race to Erase MS         Race to Erase MS                     $10,000.00
 
Radiological Society of  103rd Scientific Assembly and         $3,500.00
 North America            Annual Meeting
 
Rare Disease United      14th Annual World Symposium--        $20,000.00
 Foundation               Lysosomal Diseases
 
Rare Genomics Institute  Patient Advoacy Leadership           $25,000.00
                          Awards and Rare Disease
                          Patient Advocate Teaching
                          Modules
 
Rare New England, Inc.   Improving Health Care                 $3,000.00
                          Experiences in the Rare
                          Disease Community
 
Read to a Child, Inc.    Read to a Child's Lunchtime           $5,000.00
                          Reading Program
 
Resolve Community        Volunteer Match                       $1,000.00
 Counseling Center,
 Inc.
 
Rheumatology             Congress Sponsorship                  $2,000.00
 Association of IOWA
 
Rheumatology             Congress Sponsorship                 $20,000.00
 Association of
 Minnesota and the
 Dakotas
 
Rheumatology             Congress Sponsorship                 $10,000.00
 Association of Nevada
 
Rheumatology Nurses      Immunology Webinar                   $50,000.00
 Society
 
Rheumatology Nurses      10th Rheumatology Nurses              $3,443.91
 Society                  Society Annual Conference
 
Rise Against Hunger      Volunteer Match                       $2,944.08
 
Rise Against Hunger      Volunteer Match                       $2,944.08
 
Rocky Mountain Multiple  MS4MS Fundraising Program             $5,000.00
 Sclerosis Center
 
Rocky Mountain Multiple  2017 Webinar Program Series           $5,000.00
 Sclerosis Center
 
Rocky Mountain Multiple  2016 Fall Education Summit            $5,000.00
 Sclerosis Center
 
Samaritans, Inc.         Youth Suicide Prevention             $25,000.00
                          Services
 
Saunders Health          2017 Night of Lights                  $2,500.00
 Services Foundation
 
Saunders Health          2016 Night of Lights                  $1,000.00
 Services Foundation
 
Save One Life, Inc.      Panel Discussion Donation               $250.00
 
Scholarship America,     TORCH Awards Program                 $11,600.00
 Inc.
 
Scholarship America,     Scholarship Program                  $39,900.00
 Inc.
 
Science Club For Girls,  10th Annual Catalyst Awards          $10,000.00
 Inc.
 
Science Club For Girls,  STEMinistas Program Expansion        $10,000.00
 Inc.
 
Society of Nuclear       Congress Sponsorship                  $1,250.00
 Medicine and Molecular
 Imaging
 
Society of Nuclear       Congress Sponsorship                  $2,200.00
 Medicine and Molecular
 Imaging
 
Society of Nuclear       Congress Sponsorship                  $7,790.00
 Medicine and Molecular
 Imaging
 
Society of Nuclear       Congress Sponsorship                  $1,800.00
 Medicine and Molecular
 Imaging
 
Special Olympics         Bio-Ball 2017                         $2,500.00
 Massachusetts Inc.
 
Sportsmen's Tennis &     Academic Enrichment Program          $12,500.00
 Enrichment Center
 
St. Francis House        Triage and Coordinated Care          $10,000.00
                          for the Poor and Homeless
                          Population
 
St. Mary's Center for    Women@Work Plus Program              $15,000.00
 Women and Children
 
State of Texas           Congress Sponsorships                $20,000.00
 Association of
 Rheumatologists
 
Temple Beth Sholom [The  Jewish Genetic Disease                $7,000.00
 Tribe]                   Awareness Screening
 
The American             Congress Sponsorship                 $20,000.00
 Association of
 Clinical
 Endocrinologists
 (AACE)
 
The American Society of  Congress Sponsorship                 $10,000.00
 Hematology
 
The Boston Home, Inc.    The Boston Home Arts Program          $5,000.00
 
The Boston Home, Inc.    Socialization & Wellness              $9,000.00
                          Program
 
The Boston Home, Inc.    Resident & Family 2017 Event         $10,000.00
                          Series
 
The Boston Home, Inc.    135 Anniversary Event                $10,000.00
 
The Community Art        Teen Media Program                   $15,000.00
 Center
 
The Community Art        General Operating Support            $10,000.00
 Center
 
The Forsyth Institute    Mobile Dental Program Service        $10,000.00
 
The Greater Boston Food  Volunteer Match                       $1,000.00
 Bank, Inc.
 
The Leukemia & Lymphoma  Light The Night Event                $10,000.00
 Society Eastern PA
 Chapter
 
The Leukemia & Lymphoma  Light The Night Event                $20,000.00
 Society, Inc.
 
The MAGIC Foundation     23rd Annual Convention                $5,000.00
 
The McCourt Foundation   Tour de South Shore--Bike/            $7,500.00
                          Walk
 
The McCourt Foundation   MS Educational Program Update        $20,000.00
 
The Menkes Foundation    The Rare Disease Film                 $3,000.00
                          Festival
 
The MS Center of St      12th Annual Trivia and               $15,000.00
 Louis                    Auction Benefit
 
The Oak Clinic           Wellness Thursday Nutrition          $21,000.00
                          for MS Seminars
 
The Oak Clinic           2017 Oak Clinic Acorn Run             $3,500.00
 
The Oak Clinic           2017 Diamond Run for MS               $5,000.00
 
The Oak Clinic           Wellness Wednesday Nutrition         $14,000.00
                          for MS Seminars
 
The Posse Foundation     STEM Posse Program                   $25,000.00
 
The Possible Project     Powering Possibilities Gala          $10,000.00
 
The Regents of the       Rare Disease Symposium               $10,000.00
 University of
 California, San
 Francisco
 
The University of Texas  Congress Sponsorship                 $10,000.00
 MD Anderson Cancer
 Center
 
Thompson Island Outward  Connections--Science                 $15,000.00
 Bound Education          Education for Boston Public
 Center, Inc.             School Students
 
Thompson Island Outward  Thompson Island 4K Trail Run          $5,000.00
 Bound Education
 Center, Inc.
 
ThyCa: Thyroid Cancer    Production and Distribution          $15,000.00
 Survivors'               of Educational Handbooks and
 Association, Inc.        Materials
 
ThyCa: Thyroid Cancer    20th International Thyroid           $35,000.00
 Survivors'               Cancer Survivors' Conference
 Association, Inc.
 
Tisch Multiple           2017 Future Without MS Gala          $10,000.00
 Sclerosis Research
 Center of New York,
 Inc.
 
Tisch Multiple           Healing MS: Online Newsletter         $8,000.00
 Sclerosis Research
 Center of New York,
 Inc.
 
Tri-State Multiple       Owensboro Autumn Walk                 $2,500.00
 Sclerosis Association
 
Tri-State Multiple       Evansville Autumn Walk                $2,500.00
 Sclerosis Association
 
Tutoring Plus of         STEAM Enrichment Programs             $7,500.00
 Cambridge, Inc.
 
UMASS Dartmouth          Allston Brighton College              $2,000.00
                          Scholarship
 
United Arizona           Congress Sponsorship                 $45,000.00
 Rheumatology Alliance
 
United Network For       Congress Sponsorship                  $8,400.00
 Organ Sharing
 
United Pompe Foundation  Reception and Early Onset            $30,000.00
                          Pompe Patient Meeting
 
United Pompe Foundation  Reception and Early Onset            $45,000.00
                          Pompe Patient Meeting
 
United Pompe Foundation  General Operating Support            $50,000.00
 
United Rheumatology      Congress Sponsorship                $130,000.00
 
United Rheumatology      Congress Sponsorship                $140,000.00
 
United States Bone and   General Program Support              $46,250.00
 Joint Initiative, NFP
 
United States Bone and   The Burden of Musculoskeletal        $25,000.00
 Joint Initiative, NFP    Diseases in the United
                          States
 
United States Bone and   Membership                           $20,000.00
 Joint Initiative, NFP
 
United States Bone and   Patient Education Programs           $80,000.00
 Joint Initiative, NFP
 
University Hospitals     40th Anniversary Bone Marrow          $5,000.00
 Health System, Inc.      Transplant Celebration
 
University Neurology,    2017 NYSMSC Annual Meeting            $5,000.00
 Inc.
 
University of            Sanofi Genzyme Biotchnology           $3,000.00
 Connecticut Foundation   College Scholarship
 
University of            Student Success Program             $200,000.00
 Massachusetts
 Foundation, Inc.
 
University of            Sanofi Genzyme Biotchnology           $4,000.00
 Massachusetts: Lowell    College Scholarship
 
University of Miami      Sanofi Genzyme Biotchnology           $1,000.00
                          College Scholarship
 
University of            Congress Sponsorship                 $23,500.00
 Minnesota--Department
 of Surgery
 
University of New        Sanofi Genzyme Biotchnology           $4,000.00
 Hampshire                College Scholarship
 
University of            Congress Sponsorship                  $2,500.00
 Pennsylvania
 
Us TOO International     13th Annual SEA Blue Prostate         $5,000.00
                          Cancer Walk & Run
 
VCU Hume-Lee Transplant  Congress Sponsorship                  $1,000.00
 Center
 
Visiting Nurse           Heroes in Health Care Gala           $10,000.00
 Association of Boston
 & Affiliates
 
VZW Sint-Aloysius Oud    Volunteer Match                       $2,000.00
 Scouts Geel
 
Washington University    Washington University Fellows         $1,500.00
 in St. Louis; Siteman    Program
 Cancer Center
 
Wentworth Institute of   Sanofi Genzyme Biotchnology             $500.00
 Technology               College Scholarship
 
West End House Boys and  Volunteer Match                       $1,000.00
 Girls Club
 
WGBH Educational         WGBH Pledge Night Event              $12,000.00
 Foundation
 
Whitehead Institute for  Expedition: Bio 2018 Program         $10,000.00
 Biomedical Research
 
Wisconsin Rheumatology   Congress Sponsorship                 $10,000.00
 Association
 
Women's Lunch Place      2017 Spaghetti Dinner                $10,000.00
 
Women's Lunch Place      Healthy Meals Program                $35,000.00
 
WORLD Symposium          Congress Sponsorship                 $40,000.00
 
WORLD Symposium          Congress Sponsorship                    $600.00
 
WORLD Symposium          Congress Sponsorship                  $1,200.00
 
WORLD Symposium          Congress Sponsorship                 $25,000.00
 
WORLD Symposium          Congress Sponsorship                 $63,000.00
 
WORLD Symposium          Congress Sponsorship                $210,000.00
 
WORLD Symposium          Congress Sponsorship                $160,000.00
 
WORLD Symposium          Congress Sponsorship                  $5,000.00
 
WriteBoston              Chelsea and WriteBoston              $18,000.00
                          Educational Programs
 
Wylder Nation            4th Annual Living Like a             $15,000.00
 Foundation               Warrior Gala
 
YMCA of Greater Boston   Summer Day Camp Scholarships         $15,000.00
                          for Low-Income Youth
 
Young Men's Christian    MS One Step Program                  $15,000.00
 Association of
 Montclair, NJ
 
ziMS Foundation          8th Annual UVA MS Event               $5,000.00
 
ziMS Foundation          7th Annual UVA MS Event               $5,000.00
 


     Sponsorships, Charitable Donations, Memberships and Fellowships
                        1st Jan 2018-31st Dec 2018
    Sanofi US and its affiliate Genzyme Corporation are committed to
   supporting sponsorships for specific activities and initiatives of
    healthcare organizations and institutions, independent medical or
professional societies, trade organizations and organized patient groups
  to improve patient care and provide information to the medical and/or
  patient communities. The goal of our charitable giving approach is to
 fund general operational support for patient/disease organizations, or
program support for community-based organizations. Sanofi US and Genzyme
    Corporation are part of the Sanofi Group, a global pharmaceutical
                                company.
 Applicant names are provided by the requestor. If applicants apply as a
  group for a single activity; all applicants may be not be identified
 above. ``Funding Amount'' is the amount that the Company funded during
  2018 identified above. ``Funding Amount'' does not include funds that
   may have been provided by other affiliated Sanofi Company Entities
                         (e.g., Sanofi Pasteur).
------------------------------------------------------------------------
   Recipient Name(s)             Activity Title          Funding Amount
------------------------------------------------------------------------
495 MetroWest            Membership                           $10,000.00
 Partnership
------------------------------------------------------------------------
ACMG                     Congress Sponsorship                 $33,000.00
------------------------------------------------------------------------
ACMG                     Congress Sponsorship                  $7,600.00
------------------------------------------------------------------------
ACMG                     Congress Sponsorship                    $500.00
------------------------------------------------------------------------
ACMG                     Congress Sponsorship                  $4,500.00
------------------------------------------------------------------------
ACTRIMS                  Congress Sponsorship                 $42,500.00
------------------------------------------------------------------------
Alabama Cancer Congress  Membership                            $4,000.00
------------------------------------------------------------------------
Alliance for             Membership                          $100,000.00
 Regenerative Medicine
------------------------------------------------------------------------
Allston Village Main     Community Event                       $1,000.00
 Streets Inc.
------------------------------------------------------------------------
American Academy of      DataDerm Program                    $350,000.00
 Dermatology
------------------------------------------------------------------------
American Academy of      Quality Innovation Center            $50,000.00
 Dermatology              (QIC) Program
------------------------------------------------------------------------
American Academy of      AccessDerm Program                  $250,000.00
 Dermatology
------------------------------------------------------------------------
American Academy of      2019 President's Fundraiser         $275,000.00
 Dermatology
------------------------------------------------------------------------
American Academy of      Practice Management Center          $100,000.00
 Dermatology              Program
------------------------------------------------------------------------
American Academy of      2018 President's Fundraiser         $275,000.00
 Dermatology
------------------------------------------------------------------------
American Academy of      Congress Sponsorship                  $1,000.00
 Neurology Institute
------------------------------------------------------------------------
American Academy of      Congress Sponsorship                    $500.00
 Neurology Institute
------------------------------------------------------------------------
American Academy of      Congress Sponsorship                    $500.00
 Neurology Institute
------------------------------------------------------------------------
American Academy of      Congress Sponsorship                 $15,000.00
 Neurology Institute
------------------------------------------------------------------------
American Academy of      Congress Sponsorship                 $81,000.00
 Neurology Institute
------------------------------------------------------------------------
American Academy of      Congress Sponsorship                $598,935.00
 Neurology Institute
------------------------------------------------------------------------
American Academy of      Women Leading in Neurology           $20,000.00
 Neurology Institute      Program
------------------------------------------------------------------------
American Academy of      Transforming Leaders Program         $25,000.00
 Neurology Institute
------------------------------------------------------------------------
American Academy of      Palatucci Advocacy Leadership        $30,000.00
 Neurology Institute      Forum
------------------------------------------------------------------------
American Academy of      2018 Industry Roundtable             $50,000.00
 Neurology Institute
------------------------------------------------------------------------
American Academy of      Diversity Leadership Program         $30,000.00
 Neurology Institute
------------------------------------------------------------------------
American Association     Congress Sponsorship                 $26,500.00
 for Pediatric
 Ophthalmology &
 Strabismus
------------------------------------------------------------------------
American Association of  Congress Sponsorship                    $100.00
 Clinical
 Endocrinologists
------------------------------------------------------------------------
American Association of  Congress Sponsorship                 $50,000.00
 Neuromuscular &
 Electrodiagnostic
 Medicine
------------------------------------------------------------------------
American Association of  Congress Sponsorship                  $2,100.00
 Neuromuscular &
 Electrodiagnostic
 Medicine
------------------------------------------------------------------------
American Association of  Congress Sponsorship                    $990.00
 Neuromuscular &
 Electrodiagnostic
 Medicine
------------------------------------------------------------------------
American City Business   Corporate Citizenship Awards          $5,500.00
 Journals, Inc.           2018
------------------------------------------------------------------------
American College of      Industry Advisory Council            $60,000.00
 Chest Physicians         2018
------------------------------------------------------------------------
American College of      Congress Sponsorship                  $7,600.00
 Medical Genetics and
 Genomics
------------------------------------------------------------------------
American College of      Congress Sponsorship                 $17,500.00
 Medical Genetics and
 Genomics
------------------------------------------------------------------------
American College of      Congress Sponsorship                 $10,000.00
 Medical Genetics and
 Genomics
------------------------------------------------------------------------
American College of      Fellowship Program                   $75,000.00
 Medical Genetics
 Foundation
------------------------------------------------------------------------
American College of      Fellowship Program                   $75,000.00
 Medical Genetics
 Foundation
------------------------------------------------------------------------
American College of      Congress Sponsorship                 $10,000.00
 Rheumatology
------------------------------------------------------------------------
American College of      Congress Sponsorship                 $15,000.00
 Rheumatology
------------------------------------------------------------------------
American Society for     Conference Sponsorship               $10,000.00
 Blood and Marrow
 Transplant
------------------------------------------------------------------------
American Society for     Sarah Cannon Blood Cancer            $10,000.00
 Blood and Marrow         Network Event
 Transplant
------------------------------------------------------------------------
American Society for     ASBMT Website Sponsorship            $15,000.00
 Blood and Marrow
 Transplant
------------------------------------------------------------------------
American Society of      Congress Sponsorship                $118,000.00
 Clinical Oncology
------------------------------------------------------------------------
American Society of      Congress Sponsorship                $358,750.00
 Clinical Oncology
------------------------------------------------------------------------
American Society of      Congress Sponsorship                $285,500.00
 Hematology
------------------------------------------------------------------------
American Society of      Congress Sponsorship                 $75,000.00
 Hematology
------------------------------------------------------------------------
American Society of      Congress Sponsorship                  $3,000.00
 Human Genetics
------------------------------------------------------------------------
American Society of      Congress Sponsorship                  $5,000.00
 Nephrology
------------------------------------------------------------------------
American Society of      Congress Sponsorship                  $3,600.00
 Nephrology
------------------------------------------------------------------------
American Society of      Congress Sponsorship                 $25,000.00
 Transplant Surgeons
------------------------------------------------------------------------
American Society of      Congress Sponsorship                 $36,750.00
 Transplant Surgeons
------------------------------------------------------------------------
American Thoracic        ATS 2018 Corporate Member            $50,000.00
 Society                  Program
------------------------------------------------------------------------
American Thyroid         Congress Sponsorship                  $5,000.00
 Association
------------------------------------------------------------------------
American Transplant      Congress Sponsorship                $153,000.00
 Congress
------------------------------------------------------------------------
Americas Committee for   Congress Sponsorship                 $42,500.00
 Treatment and Research
 in Multiple Sclerosis,
 Inc.
------------------------------------------------------------------------
Americas Committee for   Congress Sponsorship                 $12,480.00
 Treatment and Research
 in Multiple Sclerosis,
 Inc.
------------------------------------------------------------------------
Americas Committee for   Congress Sponsorship                 $19,000.00
 Treatment and Research
 in Multiple Sclerosis,
 Inc.
------------------------------------------------------------------------
America's Physician      Congress Sponsorship                  $4,500.00
 Groups
------------------------------------------------------------------------
ANERA (American Near     Anera 50th Anniversary               $10,000.00
 East Refugee Aid)        Fundraiser
------------------------------------------------------------------------
Ann & Robert H. Lurie    MPS Patient and Family Day            $2,500.00
 Children's Hospital of
 Chicago
------------------------------------------------------------------------
Ann & Robert H. Lurie    Fellowship Program                   $75,000.00
 Children's Hospital of
 Chicago
------------------------------------------------------------------------
Ann & Robert H. Lurie    Fellowship Program                   $75,000.00
 Children's Hospital of
 Chicago
------------------------------------------------------------------------
Arthritis Foundation     Congress Sponsorship                  $7,500.00
 Northern California
 Office
------------------------------------------------------------------------
Arts & Business Council  Battle of the Biotech Bands           $5,250.00
 of Greater Boston,
 Inc.
------------------------------------------------------------------------
ASCO Exhibits            Congress Sponsorship                  $5,495.00
 Management
------------------------------------------------------------------------
ASCO Exhibits            Congress Sponsorship                 $18,990.00
 Management
------------------------------------------------------------------------
Asembia Specialty        Congress Sponsorship                 $20,000.00
 Pharmacy Summit LLC
------------------------------------------------------------------------
Asembia Specialty        Congress Sponsorship                 $20,000.00
 Pharmacy Summit LLC
------------------------------------------------------------------------
Asembia Specialty        Congress Sponsorship                 $20,000.00
 Pharmacy Summit LLC
------------------------------------------------------------------------
ASN                      Congress Sponsorship                  $7,200.00
------------------------------------------------------------------------
ASN                      Congress Sponsorship                 $72,500.00
------------------------------------------------------------------------
ASPHO                    Congress Sponsorship                  $3,000.00
------------------------------------------------------------------------
Association of Managed   Congress Sponsorship                 $20,000.00
 Care Pharmacy (AMCP)
------------------------------------------------------------------------
Association of Northern  Membership                            $1,200.00
 California Oncologists
------------------------------------------------------------------------
Association of VA        Congress Sponsorship                 $10,000.00
 Hematology/Oncology
------------------------------------------------------------------------
Association of Women in  AWIR 2018 Corporate Program          $75,000.00
 Rheumatology
------------------------------------------------------------------------
Bendcare                 Congress Sponsorship                $180,000.00
------------------------------------------------------------------------
Bendcare                 Congress Sponsorship                $165,000.00
------------------------------------------------------------------------
Big Brothers Big         Mentoring Youth in Science           $15,000.00
 Sisters of Central       Technology Engineering and
 Mass Metrowest Inc.      Math (MySTEM)
------------------------------------------------------------------------
Biomedical Science       Evening of Hope 2018                 $75,000.00
 Careers Program
------------------------------------------------------------------------
Biomedical Science       Hope Scholarship 2018-2019            $7,500.00
 Careers Program
------------------------------------------------------------------------
Bleeding Disorders       Patient Education Program             $7,000.00
 Alliance Illinois
------------------------------------------------------------------------
Blue Cross Blue Shield   Congress Sponsorship                 $17,500.00
 Association
------------------------------------------------------------------------
Boston Area Rape Crisis  Medical Advocacy Program             $30,000.00
 Center
------------------------------------------------------------------------
Boston Area Rape Crisis  Medical Advocacy (MedAd)             $30,000.00
 Center                   Program
------------------------------------------------------------------------
Boston Children's        Fellowship Program                   $75,000.00
 Hospital Corporation
------------------------------------------------------------------------
Boston College           Membership                           $10,000.00
------------------------------------------------------------------------
Boston Educational       Boston Public Schools Science        $10,000.00
 Development              Fair
 Foundation, Inc.
------------------------------------------------------------------------
Boston Health Care For   Life Essentials Fund                 $35,000.00
 The Homeless Program
 Inc.
------------------------------------------------------------------------
Boston Partners in       Power Lunch, 2017-2018                $6,000.00
 Education, Inc.
------------------------------------------------------------------------
Boston Plan for          Boston Teacher Residency:            $15,000.00
 Excellence in The        Building a Diverse Pipeline
 Public Schools           of STEM Educators for BPS
 Foundation
------------------------------------------------------------------------
Boston Private Industry  2018 Corporate Contributions         $15,000.00
 Council                  Campaign
------------------------------------------------------------------------
Boston University        Congress Sponsorship                  $1,500.00
 Continuing Medical
 Education
------------------------------------------------------------------------
Bottom Line              Boston STEM Success Program          $15,000.00
------------------------------------------------------------------------
Boys and Girls Clubs of  2018 Bids for Kids Auction &         $10,000.00
 MetroWest                fundraising event
------------------------------------------------------------------------
Boys and Girls Clubs of  Operating Support                    $25,000.00
 MetroWest
------------------------------------------------------------------------
Breakthrough Greater     Full STEAM Ahead Support             $15,000.00
 Boston
------------------------------------------------------------------------
California Dermatology   Congress Sponsorship                 $15,000.00
 Physician Assistant
 Society
------------------------------------------------------------------------
California Rheumatology  Congress Sponsorship                 $50,000.00
 Alliance
------------------------------------------------------------------------
Cambridge Chamber of     Membership                            $7,250.00
 Commerce
------------------------------------------------------------------------
Cambridge Chamber of     2018 Visionary Awards                 $3,250.00
 Commerce
------------------------------------------------------------------------
Cambridge Chamber of     Community support program             $7,500.00
 Commerce
------------------------------------------------------------------------
Cambridge School         Fundraiser for Cambridge             $10,000.00
 Volunteers, Inc.         Schools
------------------------------------------------------------------------
Cambridge School         Fundraiser for Cambridge             $10,000.00
 Volunteers, Inc.         Schools
------------------------------------------------------------------------
Cambridge School         Reading Buddies--Fletcher            $16,818.00
 Volunteers, Inc.         Maynard Academy Support
------------------------------------------------------------------------
Cambridge School         Reading Buddies--Fletcher            $16,423.00
 Volunteers, Inc.         Maynard Academy Support
------------------------------------------------------------------------
Cancer Research          CRI's Webinar Series: Cancer         $25,000.00
 Institute                Immunotherapy and You
------------------------------------------------------------------------
Case Management Society  CMSA's 28th Annual Conference         $1,725.00
 of America               & Expo
------------------------------------------------------------------------
Case Management Society  CMSA's 28th Annual Conference        $14,000.00
 of America               & Expo
------------------------------------------------------------------------
Case Management Society  CMSA's 28th Annual Conference         $5,500.00
 of America               & Expo
------------------------------------------------------------------------
Case Management Society  Corporate Sponsorship of              $1,250.00
 of New England           CMSNE
------------------------------------------------------------------------
Case Management Society  Patient Education and                 $1,550.00
 of New England           Awareness Program
------------------------------------------------------------------------
Case Management Society  Patient Education and                 $1,000.00
 of New England           Awareness Program
------------------------------------------------------------------------
Center for               Congress Sponsorship                $133,900.00
 International Blood
 and Marrow Transplant
 Research
------------------------------------------------------------------------
CEO Roundtable on        Membership                           $40,000.00
 Cancer
------------------------------------------------------------------------
Charles River Community  Mom and Baby Program                 $15,000.00
 Health
------------------------------------------------------------------------
CheckOrphan              Rare Disease Page Sponsorship        $11,000.00
------------------------------------------------------------------------
Child Neurology Society  Congress Sponsorship                  $4,250.00
------------------------------------------------------------------------
Children Health and      Fellowship Program                   $75,000.00
 Research Foundation,
 Inc.
------------------------------------------------------------------------
Childrens Gaucher        Research: A novel iPSC-based         $75,000.00
 Research Fund            system to elucidate the
                          molecular mechanisms leading
                          to neuronopathic Gaucher
                          disease
------------------------------------------------------------------------
Children's Hospital      Fellowship Program                   $75,000.00
 Corporation
------------------------------------------------------------------------
Children's Hospital of   2019-2020 UCLA Intercampus           $75,000.00
 Orange County            Medical Biochemical Genetics
                          Training Program
------------------------------------------------------------------------
Children's Hospital of   Fellowship Program                   $75,000.00
 Philadelphia
------------------------------------------------------------------------
Citizen Schools          STEM Learning at Somerville's        $15,000.00
                          East Somerville Community
                          School
------------------------------------------------------------------------
Citizen Schools          STEM Learning for High-Need          $15,000.00
                          Middle School Students in
                          Somerville
------------------------------------------------------------------------
CitySprouts, Inc.        Middle School Program                 $8,000.00
------------------------------------------------------------------------
CitySprouts, Inc.        Middle School Program                 $8,000.00
------------------------------------------------------------------------
Cleveland Clinic         Congress Sponsorship                  $3,500.00
 Educational Foundation
------------------------------------------------------------------------
Coalition of Hematology  Membership                            $6,000.00
 Oncology Practices
------------------------------------------------------------------------
Collegium                32nd Symposium of the                $25,000.00
 Internationale           Collegium Internationale
 Allergologicum           Allergologicum
------------------------------------------------------------------------
Community Boating, Inc.  Operating Support                    $15,000.00
------------------------------------------------------------------------
Community Farms          Community Food Access                $15,000.00
 Outreach                 Programs
------------------------------------------------------------------------
Community Servings,      Pie in the Sky                       $10,000.00
 Inc.
------------------------------------------------------------------------
Community Servings,      General Operating Support            $30,000.00
 Inc.
------------------------------------------------------------------------
Community Servings,      Volunteer Match                       $1,000.00
 Inc.
------------------------------------------------------------------------
Community Servings,      Nutrition Program for                $30,000.00
 Inc.                     Individuals & Families
                          Affected by Multiple
                          Sclerosis and Other Acute
                          Life-Threatening Illnesses
------------------------------------------------------------------------
Consortium of Multiple   Congress Sponsorship                  $8,000.00
 Sclerosis Centers
------------------------------------------------------------------------
Consortium of Multiple   Congress Sponsorship                 $21,000.00
 Sclerosis Centers
------------------------------------------------------------------------
Consortium of Multiple   Congress Sponsorship                 $22,200.00
 Sclerosis Centers
------------------------------------------------------------------------
Consortium of Multiple   Congress Sponsorship                  $1,200.00
 Sclerosis Centers
------------------------------------------------------------------------
Consortium of Multiple   Congress Sponsorship                  $6,000.00
 Sclerosis Centers
------------------------------------------------------------------------
Consortium of Multiple   Congress Sponsorship                  $1,500.00
 Sclerosis Centers
------------------------------------------------------------------------
Consortium of Multiple   North American Registry for         $200,000.00
 Sclerosis Centers        Care and Research in
                          Multiple Sclerosis (NARCRMS)
                          2018 Support
------------------------------------------------------------------------
Cradles To Crayons Inc.  Ready for School Program             $20,000.00
------------------------------------------------------------------------
Critical Path Institute  Transplant Therapeutics              $55,000.00
                          Consortium
------------------------------------------------------------------------
DEAF, Inc.--             Deaf-Accessible Medical Case         $10,000.00
 Developmental            Management Program
 Evaluation and
 Adjustment Facilities,
 Inc.
------------------------------------------------------------------------
Deep South Cancer        2018 Magic City Cycliad               $5,000.00
 Foundation
------------------------------------------------------------------------
Dermatology Nurses       DNA 2018 Corporate Membership         $3,000.00
 Association
------------------------------------------------------------------------
Dimock Community         4th Annual Road to Wellness           $1,000.00
 Foundation Inc.          5K Walk/Run
------------------------------------------------------------------------
Dimock Community         31st Annual Fundraiser              $100,000.00
 Foundation Inc.
------------------------------------------------------------------------
Duke University          Fellowship Program                   $75,000.00
------------------------------------------------------------------------
East End House Inc.      Generating and Evaluating New        $20,000.00
                          Adventures in Science After
                          School (GENASAS)
------------------------------------------------------------------------
East End House Inc.      Generating and Evaluating New        $20,000.00
                          Adventures in Science After
                          School (GENASAS)
------------------------------------------------------------------------
Emory University         Fellowship Program                   $75,000.00
------------------------------------------------------------------------
Emory University         JScreen Jewish Genetic              $100,000.00
                          Disease Education Initiative
------------------------------------------------------------------------
Family Promise           Capital Campaign: A Place to         $25,000.00
 Metrowest Inc.           Call Home
------------------------------------------------------------------------
Florida Society of       Membership                           $25,000.00
 Clinical Oncology
------------------------------------------------------------------------
Florida Society of       Living with Prostate Cancer           $3,750.00
 Clinical Oncology
------------------------------------------------------------------------
Florida Society of       Congress Sponsorship                 $35,600.00
 Rheumatology
------------------------------------------------------------------------
Food For Free            Home Delivery--A Nutrition           $15,000.00
 Committee, Inc.          Program for Seniors and
                          People with Disabilities
------------------------------------------------------------------------
Foundation of the        Multiple Sclerosis Workforce         $31,225.00
 Consortium of MS         of the Future: Medical
 Centers                  Student Research
                          Scholarships
------------------------------------------------------------------------
Foundation of the        2018 FCMSC Neurology Resident        $10,000.00
 Consortium of MS         Annual Meeting Scientific
 Centers                  Scholarships
------------------------------------------------------------------------
Foundation of the        NARCOMS NOW 2018                     $15,000.00
 Consortium of MS
 Centers
------------------------------------------------------------------------
Foundation of the        Foundation of the Consortium         $10,000.00
 Consortium of MS         of Multiple Sclerosis
 Centers                  Centers 2018 Mission Support
------------------------------------------------------------------------
Framingham Townwide Pto  Barbieri school holiday gift          $1,000.00
 Council                  drive
------------------------------------------------------------------------
Franciscan Hospital For  Adaptive Sports Program              $15,000.00
 Children Inc.
------------------------------------------------------------------------
Friends of Resiliency    Dropout Prevention Academic          $10,000.00
 for Life Inc.            Services
------------------------------------------------------------------------
Generation Citizen Inc.  Generation Citizen                   $10,000.00
                          Massachusetts Civics Day
------------------------------------------------------------------------
Generation Citizen Inc.  Volunteer Match                       $1,000.00
------------------------------------------------------------------------
Georgia Dermatology of   Congress Sponsorship                 $35,000.00
 Physician Assistants
 (GDPA)
------------------------------------------------------------------------
Georgia Society of       Membership                            $6,000.00
 Clinical Oncology
------------------------------------------------------------------------
Georgia Society of       Congress Sponsorship                 $10,000.00
 Dermatology and
 Dermatologic Surgery
------------------------------------------------------------------------
Georgia Society of       Congress Sponsorship                 $10,000.00
 Rheumatology
------------------------------------------------------------------------
Georgia Society of       Congress Sponsorship                  $2,100.00
 Rheumatology
------------------------------------------------------------------------
Girl Scouts of Eastern   Girls Building Self-eSTeEM           $15,000.00
 Massachusetts Inc.
------------------------------------------------------------------------
Global Academy for       Congress Sponsorship                 $65,000.00
 Medical Education,
 Inc.
------------------------------------------------------------------------
Global Academy for       Congress Sponsorship                 $40,037.50
 Medical Education,
 Inc.
------------------------------------------------------------------------
Global Alliance for      Membership                           $50,000.00
 Patient Access
------------------------------------------------------------------------
Global Genes             In-kind donation                     $11,128.38
------------------------------------------------------------------------
Global Genes             Access Program                       $25,000.00
------------------------------------------------------------------------
Global Genes             2018 Patient Advocacy Summit:         $2,500.00
                          Advocacy Support
------------------------------------------------------------------------
Global Genes             2018 RARE Corporate Alliance         $25,000.00
------------------------------------------------------------------------
Global Genes             2018 Patient Advocacy Summit         $50,000.00
------------------------------------------------------------------------
Global Genes             RARE Global Advocacy                 $10,000.00
                          Leadership Symposium
------------------------------------------------------------------------
Global Genes             2018 RARE Education Programs         $25,000.00
------------------------------------------------------------------------
Global Genes             2018 Rare Disease Hub                 $5,000.00
------------------------------------------------------------------------
Global Genes             2019 Corporate Alliance              $25,000.00
------------------------------------------------------------------------
Gordon Research          Lysosomal storage diseases           $10,000.00
 Conferences              Program
------------------------------------------------------------------------
Greater Boston Chamber   Membership                            $4,000.00
 of Commerce
------------------------------------------------------------------------
Greenwood Genetic        Fellowship Program                   $74,764.00
 Center Inc.
------------------------------------------------------------------------
Greenwood Genetic        Fellowship Program                   $74,991.00
 Center Inc.
------------------------------------------------------------------------
Habitat For Humanity     Fundraiser Event                     $10,000.00
 Metrowest--Greater
 Worcester Inc.
------------------------------------------------------------------------
Habitat For Humanity     Affordable Home Build Program        $20,000.00
 Metrowest--Greater
 Worcester Inc.
------------------------------------------------------------------------
Habitat For Humanity of  Corporate Build Day                   $1,500.00
 North Central
 Massachusetts
------------------------------------------------------------------------
Harvard Medical School   Congress Sponsorship                  $2,500.00
 Global and Continuing
 Education
------------------------------------------------------------------------
Health Care For All      Framingham Area Health Care          $15,000.00
 Inc.                     Access Education and
                          Outreach Campaign
------------------------------------------------------------------------
Health Resources in      The Leaders through                  $25,000.00
 Action Inc.              Education, Action and Hope
                          (LEAH) Project
------------------------------------------------------------------------
Health Resources in      The Leaders through                     $866.75
 Action Inc.              Education, Action and Hope
                          (LEAH) Project
------------------------------------------------------------------------
Hearts & Noses Hospital  Ongoing Bedside Hospital             $15,000.00
 Clown Troupe Inc.        Clown Visits to Ill and
                          Disabled Children in Greater
                          Boston
------------------------------------------------------------------------
Hemostasis and           Membership                           $10,000.00
 Thrombosis Research
 Society
------------------------------------------------------------------------
Hope and Comfort Inc.    Hope and Comfort: Personal           $10,000.00
                          Hygiene Products to Low-
                          Income Individuals and
                          Families
------------------------------------------------------------------------
Horizons for Homeless    STEAM Education for Young            $10,000.00
 Children                 Homeless Children
------------------------------------------------------------------------
Illinois Society of      Congress Sponsorship                 $25,000.00
 Dermatology Physicians
 Assistants
------------------------------------------------------------------------
Imedex, LLC              Congress Sponsorship                 $99,900.00
------------------------------------------------------------------------
Institute for Cancer     2018 In Vino Vita Fundraising        $10,000.00
 Research dba The         Event
 Research Institute of
 Fox Chase Cancer
 Center
------------------------------------------------------------------------
International Eczema     Congress Sponsorship                $200,000.00
 Council
------------------------------------------------------------------------
International Institute  2018 Golden Door Award               $10,000.00
 of New England           Fundraiser
------------------------------------------------------------------------
International Institute  Healthcare Navigation for            $15,000.00
 of New England           Refugees in Boston
------------------------------------------------------------------------
International Myeloma    Congress Sponsorship                $450,000.00
 Workshop, c/o SPARGO,
 Inc.
------------------------------------------------------------------------
International            2018 MS Perspectives Program         $40,000.00
 Organization of
 Multiple Sclerosis
 Nurses
------------------------------------------------------------------------
International            2018 IOMSN Mission Support           $10,000.00
 Organization of
 Multiple Sclerosis
 Nurses
------------------------------------------------------------------------
International Society    Congress Sponsorship                 $11,799.99
 on Thrombosis and
 Haemostasis
------------------------------------------------------------------------
Italian Home For         Volunteer Match                       $1,000.00
 Children Inc.
------------------------------------------------------------------------
Italian Home For         Comprehensive Care for               $12,500.00
 Children Inc.            Children
------------------------------------------------------------------------
Jewish Family Service    Patient Navigator/Enhanced           $20,000.00
 of Metrowest Inc.        Medical Escort Program
------------------------------------------------------------------------
Jewish Genetic Disease   JGDC Website and Social Media         $5,000.00
 Consortium (JGDC)        Rebuild Phase Two and
                          Brochure Update
------------------------------------------------------------------------
Jewish Genetic Diseases  Our Heritage and our Health--           $975.00
 Center of Greater        Ashkenazi Jewish Genetic
 Phoenix                  Disease and the Founder
                          Effect
------------------------------------------------------------------------
Just-A-Start             Just-A-Start Biomedical              $25,000.00
 Corporation              Careers Program
------------------------------------------------------------------------
Just-A-Start             Biomedical Careers Program (&        $25,000.00
 Corporation              Mass Bio Membership)
------------------------------------------------------------------------
Kansas University        Fellowship Program                   $75,000.00
 Endowment Association
------------------------------------------------------------------------
Knect365 US, Inc.        Selections from DISORDER the         $15,000.00
                          Rare Disease Film Festival
                          at Biotech Week Boston
------------------------------------------------------------------------
Kometa Serbian           Volunteer Match                       $1,000.00
 Childrens Program Inc.
------------------------------------------------------------------------
Life Science Cares Inc.  2018 Impact Breakfast                $10,000.00
------------------------------------------------------------------------
Little Brothers/Friends  Medical Escort Program                $5,000.00
 of the Elderly
------------------------------------------------------------------------
Louisiana Association    Congress Sponsorship                  $5,285.00
 of Health Plans
------------------------------------------------------------------------
Lycee International De   Fundraiser Event                     $10,000.00
 Boston International
 School of Boston Inc.
------------------------------------------------------------------------
Lysosomal and Rare       Fellowship Program                   $75,000.00
 Disorders Research and
 Treatment Center Inc.
------------------------------------------------------------------------
Lysosomal and Rare       Fellowship Program                   $75,000.00
 Disorders Research and
 Treatment Center Inc.
------------------------------------------------------------------------
Magellan Rx Management   Congress Sponsorship                  $7,500.00
 Inc.
------------------------------------------------------------------------
Margaret Fuller          Margaret Fuller Neighborhood         $15,000.00
 Neighborhood House       House Youth Programs
------------------------------------------------------------------------
Mass Insight Education   Mass Insight's Advanced              $15,000.00
 and Research Institute   Placement (AP) STEM &
 Inc                      English Program
------------------------------------------------------------------------
Massachusetts Bay        STEM Mentor Program (SMP)            $43,000.00
 Community College
 Foundation
------------------------------------------------------------------------
Massachusetts            Congress Sponsorship                $100,000.00
 Biotechnology Council
------------------------------------------------------------------------
Massachusetts            Membership                           $30,800.00
 Biotechnology Council
------------------------------------------------------------------------
Massachusetts            Patient Advocacy Summit              $10,000.00
 Biotechnology Council
------------------------------------------------------------------------
Massachusetts            Conference Sponsorship                $5,000.00
 Biotechnology
 Education Foundation
 Inc.
------------------------------------------------------------------------
Massachusetts            2018 Champions for                    $5,000.00
 Biotechnology            Biotechnology Education
 Education Foundation     Program
 Inc.
------------------------------------------------------------------------
Massachusetts            Life Sciences Workforce 2018          $5,000.00
 Biotechnology
 Education Foundation
 Inc.
------------------------------------------------------------------------
Massachusetts            MassBioEd Mission                    $50,000.00
 Biotechnology
 Education Foundation
 Inc.
------------------------------------------------------------------------
Massachusetts Black      2018 Ida B. Wells Annual              $5,000.00
 Women Attorneys          Awards Event
 Foundation Inc.
------------------------------------------------------------------------
Massachusetts College    Next Generation of Women             $10,000.00
 of Pharmacy and Health   Leaders in STEM
 Sciences
------------------------------------------------------------------------
Massachusetts Life       Massachusetts Next Generation        $50,000.00
 Sciences Center          Initiative (MassNextGen)
------------------------------------------------------------------------
Massachusetts State      2018 Fair Operations & Sanofi        $50,000.00
 Science and              Genzyme Science Award
 Engineering Fair, Inc.
------------------------------------------------------------------------
Medical Oncology         Membership                           $10,000.00
 Association of
 Southern California,
 Inc.
------------------------------------------------------------------------
MedStar Health           Congress Sponsorship                  $2,500.00
------------------------------------------------------------------------
Metrowest Free Medical   Access to Women's Health Care        $15,000.00
 Program Inc.             Program
------------------------------------------------------------------------
Michigan Society of      Membership                           $12,000.00
 Hematology & Oncology
------------------------------------------------------------------------
Museum of Fine Arts      Membership                           $20,000.00
------------------------------------------------------------------------
Museum of Science        Sanofi Genzyme Teacher               $71,520.00
                          Sabbatical at the Museum of
                          Science Cohort Year 2018/19
------------------------------------------------------------------------
National Comprehensive   2019 NCCN Global Corporate           $15,000.00
 Cancer Network           Council Membership
------------------------------------------------------------------------
National Comprehensive   NCCN 13th Annual Congress:           $10,000.00
 Cancer Network           Hematologic MalignanciesTM:
                          Patient Advocacy Pavilion
------------------------------------------------------------------------
National Organization    Congress Sponsorship                  $3,000.00
 of Rheumatology
 Managers
------------------------------------------------------------------------
National Organization    Corporate Membership                 $30,000.00
 of Rheumatology
 Managers
------------------------------------------------------------------------
National Society of      Congress Sponsorship                  $2,500.00
 Genetic Counselors
------------------------------------------------------------------------
National Society of      Congress Sponsorship                  $2,500.00
 Genetic Counselors
------------------------------------------------------------------------
National Society of      Congress Sponsorship                    $375.00
 Genetic Counselors
------------------------------------------------------------------------
NEHI                     NEHI's 2018 Innovators in            $10,000.00
                          Health Awards
------------------------------------------------------------------------
New York University--    Fellowship Program                   $75,000.00
 Langone School of
 Medicine
------------------------------------------------------------------------
NJ Sharing Network       Congress Sponsorship                  $5,000.00
------------------------------------------------------------------------
NJ Society of Oncology   Membership                            $5,000.00
 Managers
------------------------------------------------------------------------
Nora's Home              Congress Sponsorship                  $5,000.00
------------------------------------------------------------------------
North Carolina Oncology  Membership                            $5,000.00
 Management Society
------------------------------------------------------------------------
Northeastern University  Community Student Scholarship         $4,000.00
                          Program
------------------------------------------------------------------------
Northern California      Congress Sponsorship                 $10,000.00
 Rheumatology Society
------------------------------------------------------------------------
Norton Healthcare        2018 Neuroscience Expo                $5,000.00
 Foundation, Inc.
------------------------------------------------------------------------
Norton Healthcare        2018 Celebrating MS                   $5,000.00
 Foundation, Inc.         Innovations
------------------------------------------------------------------------
NSGC                     Congress Sponsorship                  $6,600.00
------------------------------------------------------------------------
Ohio Hematology          Membership                            $5,000.00
 Oncology Society
------------------------------------------------------------------------
Operation Warm Inc.      2018 Boston Coat Program             $20,000.00
------------------------------------------------------------------------
Organ Donation &         2018 Corporate Sponsorship            $5,000.00
 Transplantation
 Alliance
------------------------------------------------------------------------
Pan American League of   Congress Sponsorship                $131,750.00
 Associations for
 Rheumatology
------------------------------------------------------------------------
PCMA Pharmaceutical      Congress Sponsorship                 $56,000.00
 Care Management
 Association
------------------------------------------------------------------------
PCMA Pharmaceutical      Congress Sponsorship                 $50,000.00
 Care Management
 Association
------------------------------------------------------------------------
PCMA Pharmaceutical      Congress Sponsorship                 $36,000.00
 Care Management
 Association
------------------------------------------------------------------------
PCMA Pharmaceutical      Congress Sponsorship                 $50,000.00
 Care Management
 Association
------------------------------------------------------------------------
Peer Health Exchange     Peer Health Exchange:                 $5,000.00
 Inc.                     Empowering Boston's Young
                          People to Make Healthy
                          Decisions
------------------------------------------------------------------------
Pennsylvania             Congress Sponsorship                 $10,000.00
 Rheumatology Society
------------------------------------------------------------------------
Perkins School for the   Technology for Success in            $20,000.00
 Blind                    STEM Learning
------------------------------------------------------------------------
Philadelphia Rheumatism  Membership                            $1,000.00
 Society
------------------------------------------------------------------------
Phillips Brooks House    Bridges Food Science and              $3,000.00
 Association              Physical Fitness Workshop
 Incorporated
------------------------------------------------------------------------
Phoenix Rheumatology     Congress Sponsorship                 $10,000.00
 Association
------------------------------------------------------------------------
Phoenix Rheumatology     Congress Sponsorship                 $30,000.00
 Association
------------------------------------------------------------------------
Phoenix Rheumatology     Membership                           $10,000.00
 Association
------------------------------------------------------------------------
Premier Oncology         Membership                            $5,000.00
 Hematology Management
 Society
------------------------------------------------------------------------
Premier Oncology         Membership                            $5,000.00
 Hematology Management
 Society
------------------------------------------------------------------------
Premier Specialty        Congress Sponsorship                 $15,000.00
 Network
------------------------------------------------------------------------
President and Fellows    The Family Van: Culturally-          $50,000.00
 of Harvard College       Competent Care for All
------------------------------------------------------------------------
President and Fellows    The Family Van: Increasing           $50,000.00
 of Harvard College       Healthcare Access to
                          Everyone
------------------------------------------------------------------------
Pri-Med Institute        Congress Sponsorship                 $66,750.00
------------------------------------------------------------------------
Pro Player Foundation    Patient Education and                 $5,000.00
                          Awareness Program
------------------------------------------------------------------------
Pro Player Foundation    Patient Education and                 $5,000.00
                          Awareness Program
------------------------------------------------------------------------
Project Just Because,    211 Domestic Abuse/Emergency         $10,000.00
 Inc.                     Program & Keep A Family Warm
                          Program
------------------------------------------------------------------------
Prostate Cancer Academy  Congress Sponsorship                  $7,500.00
------------------------------------------------------------------------
Read to a Child, Inc.    Read to a Child's Lunchtime           $5,000.00
                          Reading Program
------------------------------------------------------------------------
Regents of the           Fellowship Program                   $75,000.00
 University of
 California
------------------------------------------------------------------------
Regents of the           Lysosomal Storage Diseases           $57,059.40
 University of            Patient and Family
 California               Educational Grant
------------------------------------------------------------------------
Regents of the           Fellowship Program                   $75,000.00
 University of Michigan
------------------------------------------------------------------------
Regents of the           Fellowship Program                   $75,000.00
 University of
 Minnesota
------------------------------------------------------------------------
Rheumatology             Congress Sponsorship                  $7,500.00
 Association of Iowa
------------------------------------------------------------------------
Rheumatology             Congress Sponsorship                 $20,000.00
 Association of Iowa
------------------------------------------------------------------------
Rheumatology             Congress Sponsorship                 $10,000.00
 Association of
 Minnesota and the
 Dakotas
------------------------------------------------------------------------
Rheumatology             Congress Sponsorship                 $10,000.00
 Association of Nevada
------------------------------------------------------------------------
Rheumatology Nurses      Congress Sponsorship                  $2,000.00
 Society
------------------------------------------------------------------------
Rheumatology Nurses      Congress Sponsorship                 $45,000.00
 Society
------------------------------------------------------------------------
Rheumatology Nurses      Congress Sponsorship                  $3,655.00
 Society
------------------------------------------------------------------------
Rheumatology Nurses      Congress Sponsorship                 $33,575.00
 Society
------------------------------------------------------------------------
Rheumatology Nurses      Congress Sponsorship                  $1,700.00
 Society
------------------------------------------------------------------------
Rheumatology Nurses      National Advocacy Sponsorship        $50,000.00
 Society
------------------------------------------------------------------------
Rheumatology Nurses      Speed Advocacy Session of the         $7,500.00
 Society                  RNS Advocacy Experience Day
------------------------------------------------------------------------
Rheumatology Nurses      Corporate Sponsorship                $50,000.00
 Society
------------------------------------------------------------------------
Rhode Island Diabetes &  Congress Sponsorship                    $750.00
 Endocrine Society
------------------------------------------------------------------------
Run for Dad American     Run for Dad                           $3,000.00
 Cancer Society
------------------------------------------------------------------------
S S Cosmas & Damian      92nd Annual Feast of S.S.             $2,500.00
 Society Inc.             Cosmas and Damian
------------------------------------------------------------------------
Samaritans, Inc.         Youth Suicide Prevention             $25,000.00
                          Services
------------------------------------------------------------------------
Scholarship America,     Chart Your Own Course                $32,250.00
 Inc.                     Scholarship Program
------------------------------------------------------------------------
Scholarship America,     Sanofi Genzyme TORCH Awards          $11,600.00
 Inc.                     program
------------------------------------------------------------------------
Science Club For Girls   Science Clubs and Junior             $10,000.00
 Inc.                     Mentors Program
------------------------------------------------------------------------
Science From Scientists  In-School Module-Based (ISMB)        $30,000.00
 Inc.                     STEM Enrichment Program for
                          Boston Public Schools 2017-
                          18
------------------------------------------------------------------------
Science From Scientists  In-School Module-Based (ISMB)        $30,000.00
 Inc.                     STEM Enrichment Program for
                          Boston Public Schools 2018-
                          19
------------------------------------------------------------------------
Society for              Congress Sponsorship                 $20,000.00
 Investigative
 Dermatology
------------------------------------------------------------------------
Southern Oncology        Membership                            $5,000.00
 Association of
 Practices
------------------------------------------------------------------------
Southern Regional        Congress Sponsorship                  $2,000.00
 Genetics Group (SERGG)
------------------------------------------------------------------------
Special Olympics         2018 Bio-Ball                         $2,500.00
 Massachusetts Inc.
------------------------------------------------------------------------
Special Olympics         Special Olympics                      $7,500.00
 Massachusetts Inc.       Massachusetts Shrewsbury
                          Basketball Team to Compete
                          at Special Olympics World
                          Games in Abu Dhabi
------------------------------------------------------------------------
Sportsmen's Tennis &     School to Sportsmen's Program        $15,000.00
 Enrichment Center
------------------------------------------------------------------------
St. Francis House        Triage Program                       $10,000.00
------------------------------------------------------------------------
St. Mary's Center for    Women@Work Plus                      $15,000.00
 Women and Children
------------------------------------------------------------------------
State of Texas           Congress Sponsorship                 $40,000.00
 Association of
 Rheumatologists
------------------------------------------------------------------------
State of Texas           Congress Sponsorship                 $40,000.00
 Association of
 Rheumatologists
------------------------------------------------------------------------
The Administrators of    NOLA Bluedoo Run/Walk/                $7,500.00
 the Tulane Education     Celebration for Prostate
 Fund on behalf of        Cancer Research
 Tulane University
 Health Sciences
 Center, CCE
------------------------------------------------------------------------
The American Society of  Congress Sponsorship                 $10,000.00
 Hematology
------------------------------------------------------------------------
The American Society of  Congress Sponsorship                  $3,150.00
 Hematology
------------------------------------------------------------------------
The Boston Home, Inc.    B.Fit! Socialization and             $18,000.00
                          Wellness Day Program
------------------------------------------------------------------------
The Community Art        Community Art Center Youth           $15,000.00
 Center                   Programming
------------------------------------------------------------------------
The Community Art        Community Art Center School          $15,000.00
 Center                   Age Child Care and Teen
                          Programs
------------------------------------------------------------------------
The Discovery Museums    Sanofi Genzyme Discovery             $15,000.00
                          Science 2018
------------------------------------------------------------------------
The Discovery Museums    Fundraiser Event                      $5,000.00
------------------------------------------------------------------------
The Discovery Museums    Discovery Science: Framingham        $15,000.00
                          and Waltham
------------------------------------------------------------------------
The Endocrine Society    Congress Sponsorship                  $3,995.00
------------------------------------------------------------------------
The Forsyth Institute    Mobile Dental Program Service        $10,000.00
                          to the Youth on Fire Shelter
                          in Cambridge
------------------------------------------------------------------------
The Greater Boston Food  General Operating Support            $30,000.00
 Bank Inc.
------------------------------------------------------------------------
The Greater Boston Food  Volunteer Match                       $1,000.00
 Bank Inc.
------------------------------------------------------------------------
The Greater Boston Food  Volunteer Match                       $1,000.00
 Bank Inc.
------------------------------------------------------------------------
The Greater Boston Food  Emergency Food Distribution          $30,000.00
 Bank Inc.                Across Eastern Massachusetts
------------------------------------------------------------------------
The Jewish P.O.C.E.T.    Congress Sponsorship                  $2,500.00
------------------------------------------------------------------------
The Massachusetts        Everyday Amazing Race                 $5,000.00
 General Hospital
------------------------------------------------------------------------
The McCourt Foundation   Educational Update                   $20,000.00
------------------------------------------------------------------------
The McCourt Foundation   Tour de South Shore Athletic          $5,000.00
                          Festival
------------------------------------------------------------------------
The McCourt Foundation   MS Educational Update for            $20,000.00
                          Patients, Caregivers and
                          Family Members
------------------------------------------------------------------------
The Oak Clinic           2018 Oak Clinic Acorn Run             $4,500.00
------------------------------------------------------------------------
The Oak Clinic           Oak Clinic's Marvelous               $15,000.00
                          Monday's Wellness Programs
------------------------------------------------------------------------
The Oak Clinic           2018 Oak Clinic Diamond Run           $5,000.00
------------------------------------------------------------------------
The Posse Foundation     Posse Boston                         $25,000.00
 Inc.
------------------------------------------------------------------------
The Possible Project     The Possible Project 2018            $10,000.00
                          Event Series
------------------------------------------------------------------------
The Regents of the       Fellowship Program                   $75,000.00
 University of
 California, Irvine
------------------------------------------------------------------------
The Regents of the       Fellowship Program                   $75,000.00
 University of
 California, Los
 Angeles
------------------------------------------------------------------------
The Salvation Army       Volunteer Match                       $2,000.00
------------------------------------------------------------------------
The Salvation Army       Volunteer Match                       $6,000.00
------------------------------------------------------------------------
The UCLA Foundation      The UCLA Fabry Disease                $2,500.00
                          Program
------------------------------------------------------------------------
Thompson Island Outward  Connections Program                  $15,000.00
 Bound Education Center
 Inc.
------------------------------------------------------------------------
Thompson Island Outward  2018 Thompson Island 4k Trail         $5,000.00
 Bound Education Center   Run
 Inc.
------------------------------------------------------------------------
Trustees of Boston       Community Student Scholarship         $4,000.00
 University               Program
------------------------------------------------------------------------
Trustees of Boston       Community Student Scholarship           $825.00
 University               Program
------------------------------------------------------------------------
Trustees of the          The 19th International               $50,000.00
 University of            Vasculitis & ANCA Workshop
 Pennsylvania
------------------------------------------------------------------------
Tutoring Plus of         STEAM Programming                     $5,000.00
 Cambridge, Inc.
------------------------------------------------------------------------
Tutoring Plus of         Elementary and Middle School         $12,500.00
 Cambridge, Inc.          Programs
------------------------------------------------------------------------
UAB Division of          Fellowship Program                   $75,000.00
 Nephrology Attn:
 Jennifer Clendenin
------------------------------------------------------------------------
UConn Health             Congress Sponsorship                    $500.00
------------------------------------------------------------------------
United Arizona           Congress Sponsorship                 $25,000.00
 Rheumatology Alliance
------------------------------------------------------------------------
United Network For       Congress Sponsorship                  $9,100.00
 Organ Sharing
------------------------------------------------------------------------
United Network For       Congress Sponsorship                  $6,000.00
 Organ Sharing
------------------------------------------------------------------------
United Network For       Congress Sponsorship                  $8,000.00
 Organ Sharing
------------------------------------------------------------------------
United Rheumatology LLC  Congress Sponsorship                $135,000.00
------------------------------------------------------------------------
United Way of Tri-       Volunteer Match                       $1,000.00
 County
------------------------------------------------------------------------
University of Alabama    Fellowship Program                   $75,000.00
 at Birmingham
------------------------------------------------------------------------
University of Chicago    Congress Sponsorship                 $15,000.00
 Hospitals
------------------------------------------------------------------------
University of Colorado   Congress Sponsorship                 $20,000.00
 Anschutz Medical
 Campus
------------------------------------------------------------------------
University of Florida    Fellowship Program                   $75,000.00
 Foundation Inc.
------------------------------------------------------------------------
University of Florida    Fellowship Program                   $74,900.00
 Foundation Inc.
------------------------------------------------------------------------
University of Illinois   Congress Sponsorship                 $10,000.00
 at Chicago
------------------------------------------------------------------------
University of            Congress Sponsorship                 $10,000.00
 Louisville
------------------------------------------------------------------------
University of            Student Success Program,            $200,000.00
 Massachusetts            UMass Boston, College of
 Foundation Inc.          Science and Mathematics
------------------------------------------------------------------------
University of            TORCH award donations                 $5,000.00
 Mississippi Foundation
------------------------------------------------------------------------
Uplifting Athletes Inc.  Leadership Development               $38,000.00
                          Conference/Organizational
                          Support
------------------------------------------------------------------------
Uplifting Athletes Inc.  2019 Uplifting Athletes Young        $20,000.00
                          Investigator Draft
------------------------------------------------------------------------
Uplifting Athletes Inc.  Young Investigator Draft              $5,000.00
------------------------------------------------------------------------
Vanderbilt University    Fellowship Program                   $75,000.00
 School of Medicine
------------------------------------------------------------------------
VNA Care Hospice Inc.    Elizabeth Evarts de Rham              $5,000.00
                          Hospice Home at Chilton
                          Street
------------------------------------------------------------------------
Wade Institute for       Summer Professional                  $20,000.00
 Science Education        Development STEM Institutes
                          for teachers
------------------------------------------------------------------------
Wade Institute for       Summer Professional                  $20,000.00
 Science Education        Development Institutes for
                          Science Teachers 2019
------------------------------------------------------------------------
Washington State         Membership                            $5,000.00
 Medical Oncology
 Society
------------------------------------------------------------------------
Wentworth Institute of   Community Student Scholarship         $4,000.00
 Technology               Program
------------------------------------------------------------------------
West End House Boys and  Volunteer Match                       $1,000.00
 Girls Club
------------------------------------------------------------------------
West End House Boys and  Volunteer Match                       $1,000.00
 Girls Club
------------------------------------------------------------------------
West End House Boys and  West End House Expect More           $24,609.00
 Girls Club               Campaign: MakerZone
------------------------------------------------------------------------
West End House Boys and  West End House Annual                $25,000.00
 Girls Club               Celebration
------------------------------------------------------------------------
West End House Boys and  West End House Annual                $50,000.00
 Girls Club               Celebration
------------------------------------------------------------------------
Western States Regional  Congress Sponsorship                 $18,000.00
 Hemophilia Network
------------------------------------------------------------------------
Wheelchairs 4 Kids       Let's Roll Program                   $10,000.00
------------------------------------------------------------------------
Whitehead Institute for  Expedition: Bio 2019                 $10,000.00
 Biomedical Research
------------------------------------------------------------------------
Wisconsin Rheumatology   Congress Sponsorship                 $10,000.00
 Association
------------------------------------------------------------------------
Women's Dermatologic     Congress Sponsorship                  $2,500.00
 Society
------------------------------------------------------------------------
Women's Lunch Place      Healthy Meals Program                $45,000.00
------------------------------------------------------------------------
WORLD Symposium          Congress Sponsorship                  $1,000.00
------------------------------------------------------------------------
WORLD Symposium          Congress Sponsorship                  $1,000.00
------------------------------------------------------------------------
WORLD Symposium          Congress Sponsorship                  $1,000.00
------------------------------------------------------------------------
WORLD Symposium          Congress Sponsorship                 $67,000.00
------------------------------------------------------------------------
WORLD Symposium          Congress Sponsorship                $110,000.00
------------------------------------------------------------------------
WORLD Symposium          Congress Sponsorship                  $5,000.00
------------------------------------------------------------------------
WORLD Symposium          Congress Sponsorship                 $50,000.00
------------------------------------------------------------------------
WORLD Symposium          Congress Sponsorship                 $60,000.00
------------------------------------------------------------------------
WORLD Symposium          Congress Sponsorship                 $35,000.00
------------------------------------------------------------------------
WORLD Symposium          Congress Sponsorship                 $35,000.00
------------------------------------------------------------------------
WORLD Symposium          Congress Sponsorship                 $50,000.00
------------------------------------------------------------------------
WORLD Symposium          Congress Sponsorship                 $50,000.00
------------------------------------------------------------------------
WORLDSymposia            Congress Sponsorship                  $5,250.00
------------------------------------------------------------------------
WORLDSymposia            Congress Sponsorship                 $45,000.00
------------------------------------------------------------------------
WriteBoston              Aligning and Elevating               $18,000.00
                          Literacy Instruction across
                          the Chelsea Public Schools
------------------------------------------------------------------------
YMCA of Greater Boston   Scholarships for Low-Income          $15,000.00
                          Allston-Brighton Children
------------------------------------------------------------------------
ziMS Foundation          2018 ZIMS Strike Down MS Bowl-        $5,000.00
                          A-Thon
------------------------------------------------------------------------


 
  Proposal Type      Project Name        Legal Name          Amount
 
Corporate         Transplantation    Critical Path            $55,000.00
 Membership        Therapeutics       Institute
                   Membership
 
Corporate         Corporate          Endocrine Society        $11,000.00
 Membership        Membership
 
Corporate         Corporate          Colorado Business         $5,000.00
 Membership        Membership         Group on Health
 
Corporate         Corporate          Rheumatology            $200,000.00
 Membership        Membership         Research
                                      Foundation
 
Corporate         Corporate          National                 $25,000.00
 Membership        Membership         Governors
                                      Association
 
Corporate         Corporate          National                  $5,000.00
 Membership        Membership         Conference of
                                      Insurance
                                      Legislato
 
Corporate         CEVR Membership    Tufts Medical            $35,000.00
 Membership                           Center
 
Corporate         Corporate          American                 $20,000.00
 Membership        Membership         Association for
                                      Cancer Research
 
Corporate         Corporate          American                 $20,000.00
 Membership        Membership         Association for
                                      Cancer Research
 
Corporate         Corporate          American                 $25,000.00
 Membership        Membership         Association of
                                      Diabetes
                                      Educator
 
Corporate         Corporate          AMGA Foundation          $15,000.00
 Membership        Membership         Inc.
 
Corporate         2018 NEHI          NEHI                     $75,000.00
 Membership        Membership
 
Corporate         2018 Corporate     National Kidney          $10,000.00
 Membership        Membership         Foundation, Inc.
 
Corporate         Corporate          The Partnership          $19,000.00
 Membership        Membership Dues    for Quality
                   2018               Medical Donati
 
Corporate         STOP Obesity       George Washington        $25,000.00
 Membership        Alliance           University's
                                      STOP Obes
 
Corporate         Premium            Texas Business           $15,000.00
 Membership        Membership         Group on Health
 
Corporate         Health             University of            $50,000.00
 Membership        Organization       Louisville
                   Corporate          School of Public
                   Membership         Health
 
Corporate         Corporate          American                 $20,000.00
 Membership        Membership         Association of
                                      Nurse
                                      Practitioner
 
Corporate         Corporate          Georgia Chamber             $750.00
 Membership        Membership         of Commerce
 
Corporate         Corporate          American                 $20,000.00
 Membership        Membership         Association of
                                      Clinical
                                      Endocrinol
 
Corporate         Corporate          National Business        $16,500.00
 Membership        Membership         Group on Health
 
Corporate         PBSM Corporate     National Business        $15,000.00
 Membership        Membership         Group on Health
 
Corporate         Membership Dues    Florida Chamber           $2,000.00
 Membership                           of Commerce,
                                      Inc.
 
Corporate         2018 Membership    Buyers Health            $10,000.00
 Membership                           Care Action
                                      Group
 
Corporate         Chamber of         Montana Chamber             $280.00
 Membership        Commerce Dues      of Commerce
 
Corporate         Corporate          Business for             $33,000.00
 Membership        Membership         Social
                                      Responsibility
 
Corporate         2018 ACCP Annual   Association of            $6,250.00
 Membership        Membership         Corporate
                                      Contributions
                                      Pro
 
Corporate         Corporate          Society of                $2,500.00
 Membership        Membership         Toxicologic
                                      Pathology
 
Corporate         Corporate          Healthcare               $45,000.00
 Membership        Membership         Distribution
                                      Alliance HDA
 
Corporate         Tufts CSDD         Tufts Center for         $15,000.00
 Membership                           the Study of
                                      Drug Developm
 
Corporate         Affiliate          Massachusetts             $2,500.00
 Membership        Membership Dues    Association of
                                      Health Plans
 
Corporate         Corporate          National Health          $32,000.00
 Membership        Membership         Council
 
Corporate         Corporate          Illinois                  $2,500.00
 Membership        Membership         Manufacturers'
                                      Association
 
Corporate         NASPA 2018         NASPA                     $5,000.00
 Membership        Associate Member
                   Dues
 
Corporate         Corporate          National LGBT             $7,500.00
 Membership        Membership 2018    Chamber of
                                      Commerce
 
Corporate         Corporate          National LGBT             $7,500.00
 Membership        Membership 2018    Chamber of
                                      Commerce
 
Corporate         Corporate          International            $20,000.00
 Membership        Membership         Society for
                                      Medical
                                      Publicatio
 
Corporate         ACPA Corporate     American Chronic         $10,000.00
 Membership        Membership         Pain Association
 
Corporate         Corporate          Pharmaceutical          $397,832.00
 Membership        Membership         Research and
                                      Manufacture
 
Corporate         Corporate          Pharmaceutical                    -
 Membership        Memberhsip         Research and
                                      Manufacture
 
Corporate         Women's Heart      Tides Center             $75,000.00
 Membership        Alliance
                   Mebership
 
Corporate         Corporate          College Diabetes         $25,000.00
 Membership        Membership         Network Inc.
 
Corporate         Corp.              AIM--Associated          $10,000.00
 Membership                           Industries of
                                      Massachuset
 
Corporate         NLGA Corporate     National Lt.             $10,000.00
 Membership        Membership         Governors
                                      Association
 
Corporate         Corporate          Ohio Chamber of           $1,700.00
 Membership        Membership         Commerce
 
Corporate         Corporate          Somerset Health           $2,500.00
 Membership        Membership         Care Foundation
 
Corporate         Corporate          Academy of               $10,000.00
 Membership        Membership         Managed Care
                                      Pharmacy
 
Corporate         Corporate          HealthCare                $5,000.00
 Membership        Membership         Institute of NJ
 
Corporate         DA4S Corporate     Diversity                   $700.00
 Membership        Membership         Alliance for
                                      Science, Inc.
 
Corporate         Corporate          Healthcare               $23,500.00
 Membership        Membership         Businesswomen's
                                      Association
 
Corporate         National Quality   National Quality         $39,400.00
 Membership        Forum Membership   Forum
 
Corporate         WPEO Corporate     Women President           $5,000.00
 Membership        Membership         Educational
                                      Organization
 
Corporate         Corporate          Minnesota Society         $6,000.00
 Membership        Membership         of Health-System
                                      Pharm
 
Corporate         Corporate          The Medical Alley         $2,000.00
 Membership        Membership         Association
 
Corporate         2018 Membership    New York & New            $6,500.00
 Membership                           Jersey Minority
                                      Supplier D
 
Corporate         Corporate          Pittsburgh                $3,450.00
 Membership        Membership         Business Group
                                      on Health
 
Corporate         GDAHC Corporate    Greater Detroit           $7,000.00
 Membership        Membership         Area Health
                                      Council, Inc.
 
Corporate         Ruby Annual        US Business               $7,500.00
 Membership        Membership         Leadership
                                      Network
 
Corporate         Ruby Annual        US Business               $7,500.00
 Membership        Membership         Leadership
                                      Network
 
Corporate         2018 Corporate     Physician                $20,000.00
 Membership        Dues               Assistant
                                      Foundation of
                                      the Americas
 
Corporate         2018 Somerset      Somerset County          $15,000.00
 Membership        County Business    Business
                   Partnership dues   Partnership
 
Corporate         Annual Membership  Women in                 $20,000.00
 Membership                           Government
                                      Foundation, Inc.
 
Corporate         CLSA Sustaining    California Life          $76,000.00
 Membership        Membership         Sciences
                                      Association
 
Corporate         NaVOBA corporate   NaVOBA--National         $15,000.00
 Membership        membership         Veteran Owned
                                      Busines
 
Corporate         Corporate          Intellectual             $26,800.00
 Membership        Membership         Property Owners
                                      Association
 
Corporate         Annual Membership  Michigan Primary          $5,000.00
 Membership                           Care Consortium
 
Corporate         Annual Membership  National Alliance        $15,000.00
 Membership                           of Healthcare
                                      Purchaser
 
Corporate         Annual Membership  ISPOR                    $15,000.00
 Membership
 
Corporate         Corporate          The Antibody             $10,000.00
 Membership        Membership         Society
 
Corporate         Corporate          Michigan                  $2,500.00
 Membership        Membership         Association of
                                      Health
 
Corporate         Corporate          Life Science              $1,500.00
 Membership        Membership         Tennessee
 
Corporate         2018 Corporate     Association of           $75,000.00
 Membership        Membership         Community Cancer
                                      Centers
 
Corporate         Corporate          Texas Association         $5,000.00
 Membership        Membership         of Manufacturers
 
Corporate         Annual Membership  JDRF                     $30,000.00
 Membership                           International
 
Corporate         Corporate          AMDA--The Sociery         $2,584.00
 Membership        Membership         for Post-Acute
                                      and Long
 
Corporate         Corporate          Texas Healthcare          $5,000.00
 Membership        Membership         and Bioscience
                                      Institute
 
Corporate         Corporate          BioForward                $3,000.00
 Membership        Membership
 
Corporate         Annual Membership  National                $224,000.00
 Membership                           Association of
                                      Manufacturers
 
Corporate         2018 Business      The Health                  $450.00
 Membership        Partner            Collaborative
                   Membership
 
Corporate         OFII 2018          Organization for         $17,500.00
 Membership        Membership Dues    International
                                      Investment
 
Corporate         AMA Foundation     American Medical         $20,000.00
 Membership        dues               Association
                                      Foundation
 
Corporate         Corporate          National                $200,000.00
 Membership        Membership Dues    Pharmaceutical
                                      Council
 
Corporate         Corporate          National                $200,000.00
 Membership        Membership Dues    Pharmaceutical
                                      Council
 
Corporate         Corporate          National                 $50,000.00
 Membership        Membership Dues    Pharmaceutical
                                      Council
 
Corporate         Biocom Membership  Biocom                   $15,000.00
 Membership        Dues
 
Corporate         2018 Preferred     BIONJ Inc.               $30,000.00
 Membership        Membership
 
Corporate         2018 Membership    Healthcare              $200,000.00
 Membership        Dues               Leadership
                                      Council
 
Corporate         Corporate          Oregon Business &         $1,500.00
 Membership        Membership         Industry
                                      Association
 
Corporate         Membership Dues    American Society         $30,000.00
 Membership                           of
                                      Transplantation
 
Corporate         Patients Count     Milken Institute         $50,000.00
 Membership        Membership Dues
 
Corporate         Membership Dues    Rheumatology            $200,000.00
 Membership                           Research
                                      Foundation
 
Corporate         Membership Dues    The Kansas                  $993.00
 Membership                           Chamber
 
Corporate         Membership Dues    Lehigh Valley             $1,500.00
 Membership                           Business
                                      Coalition on
                                      Healthcare
 
Corporate         2018 BIO           Biotechnology           $718,851.00
 Membership        Membership         Innovation
                                      Organization
 
Corporate         2018 Membership    Northeast                $10,500.00
 Membership        Dues               Business Group
                                      on Health
 
Corporate         Corporate          Indiana Chamber             $650.00
 Membership        Membership         of Commerce
 
Corporate         Corporate          American Society         $35,000.00
 Membership        Membership Dues    of Hematology
 
Corporate         Corporate          HealthCare 21             $2,750.00
 Membership        Membership         Business
                                      Coalition
 
Corporate         MichiBio           Michigan                  $1,500.00
 Membership        Membership         Biosciences
                                      Industry
                                      Association
 
Corporate         Membership Dues    Virginia Bio              $2,300.00
 Membership
 
Corporate         Corporate          American                 $50,000.00
 Membership        Membership         Foundation for
                                      Women's Health
 
Corporate         PSTC Corporate     Critical Path            $35,000.00
 Membership        Membership         Institute
 
Corporate         Corporate          Research!America         $15,000.00
 Membership        Membership Dues
 
Corporate         Membership Dues    ILSI Health and          $15,000.00
 Membership                           Environmental
                                      Health Instit
 
Corporate         Membership Dues    ILSI Health and          $82,971.00
 Membership                           Environmental
                                      Health Instit
 
Corporate         Membership Dues    Washington Health         $6,930.00
 Membership                           Alliance
 
Corporate         Membership Dues    Employers Health          $1,000.00
 Membership                           Coalition, Inc.
 
Corporate         Membership Dues    State Legislative        $35,000.00
 Membership                           Leaders
                                      Foundation, Inc.
 
Corporate         Associate          Alliance for             $50,000.00
 Membership        Sustaining         Patient Access
                   Membership Dues
 
Corporate         2018 NewYorkBIO    NewYorkBIO                $2,500.00
 Membership        Membership
 
Corporate          Membership        Michigan Chamber          $1,950.00
 Membership        Renewal            of Commerce
 
Corporate         CAHF Associate     CA Assn of Health         $1,200.00
 Membership        Membership         Facilities
                   Renewal
 
Corporate         2018 Memebership   Alliance for a           $20,000.00
 Membership                           Stronger FDA
 
Corporate         Industry Advisory  The Foundation           $25,000.00
 Membership        Board              for Post-Acute &
                                      Long-Term
 
Corporate         DTA Membership     Digital                  $75,000.00
 Membership                           Therapeutics
                                      Alliance
 
Corporate         Corporate          Public Affairs           $12,900.00
 Membership        Membership         Council
                   Renewal
 
Corporate         2018 IPAC          Diabetes                 $15,000.00
 Membership        membership         Education and
                                      Camping
                                      Associatio
 
Corporate         Annual Membership  Evidence for            $100,000.00
 Membership                           Health Care
                                      Improvement d/b
 
Corporate         Consortium for     National Academy        $100,000.00
 Membership        Value and          of Sciences
                   Science
                   Membership
 
Corporate         HRPA Membership    HR Policy                $15,000.00
 Membership                           Association
 
Corporate         CPR Membership     International            $10,000.00
 Membership                           Institute for
                                      Conflict
                                      Preventio
 
Corporate         Corporate          American                $100,000.00
 Membership        Membership         Enterprise
                                      Institute for
                                      Public Policy
 
Corporate         Annual Membership  Louisiana                 $1,765.00
 Membership                           Association of
                                      Health Plans
 
Corporate         Corporate          U.S. Capitol             $10,000.00
 Membership        Committee          Historical
                   Membership 2018    Society
 
Corporate         2018 Memebership   Well-Being                $1,000.00
 Membership                           Collaborative of
                                      Ohio
 
Corporate         2018 Council       Virginia Center           $5,000.00
 Membership        Membership         for Health
                                      Innovation
 
Corporate         Corporate          Arkansas State            $1,000.00
 Membership        Membership         Chamber of
                                      Commerce/AIA
 
Corporate         Corporate          International             $8,000.00
 Membership        Membership         Society for
                                      Pharmacoepidemi
 
Corporate         AWB Membership     Association of            $2,500.00
 Membership                           Washington
                                      Business
 
Corporate         Membership dues    Pharmaceutical                    -
 Membership                           Research and
                                      Manufacture
 
Corporate         Annual Membership  Medical                   $5,000.00
 Membership                           Association of
                                      Georgia
 
Corporate         Annual Membership  New Jersey                $5,000.00
 Membership                           Association of
                                      Health Plans
 
Corporate         Annual Membership  CECP                     $15,000.00
 Membership
 
Corporate         Corporate          Kentuckiana               $1,500.00
 Membership        Membership         Health
                                      Collaborative
 
Corporate         2018 PQA           PQA, Inc.                $34,375.00
 Membership        Membership Dues
 
Corporate         2018 CIBMTR        The Medical              $30,000.00
 Membership        Corporate          College of
                   Membership         Wisconsin, Inc.
 
Corporate         Annual Membership  American                 $75,000.00
 Membership                           Thrombosis and
                                      Hemostasis
                                      Network
 
Corporate         Annual Membership  Missouri Chamber          $1,500.00
 Membership                           of Commerce and
                                      Indust
 
Corporate         Annual membership  Center Forward           $20,000.00
 Membership
 
Corporate         PACH Associate     Partnership for         $125,000.00
 Membership        Membership         the Advancement
                                      of Cardio
 
Corporate         HUBZone            HUBZone                   $2,495.00
 Membership        Contractors        Contractors
                   National Council   National
                                      Council, Inc.
 
Corporate         Annual Membership  Greater Las Vegas         $1,499.50
 Membership                           Chamber of
                                      Commerce
 
Corporate         GlobalWIN Annual   Global Women's           $20,000.00
 Membership        Support            Innovation
                                      Network
 
Corporate         FDLI Membership    Food and Drug Law        $13,750.00
 Membership                           Institute
 
Corporate         Annual Membership  Wisconsin                   $714.00
 Membership                           Manufacturers
                                      and Commerce
 
Corporate         Annual Membership  Midwest Business          $8,000.00
 Membership                           Group on Health
 
Corporate         Corporate          National                 $25,000.00
 Membership        Membership         Committee for
                                      Quality
                                      Assurance
 
Corporate         Affiliate Partner  Central Florida           $1,800.00
 Membership        dues               Health Care
                                      Coalition
 
Corporate         MRCT Clinical      Multi Regional           $50,000.00
 Membership        Trials             Clinical Trial
                   Membership         Center of Brigha
 
Corporate         MRCT Bioethics     Multi Regional           $25,000.00
 Membership        Membership         Clinical Trial
                                      Center of Brigha
 
Corporate         MOBIO Membership   Missouri                  $1,500.00
 Membership        2018               Biotechnology
                                      Association
 
Corporate         Corporate          National Hispanic        $25,000.00
 Membership        Membership         Health
                                      Foundation
 
Corporate         Annual Membership  West Virginia             $1,320.00
 Membership                           Chamber of
                                      Commerce, Inc.
 
Corporate         Annual Membership  New Jersey                $3,000.00
 Membership                           Alliance for
                                      Action
 
Corporate         Corporate          American College          $1,500.00
 Membership        Membership         of Toxicology
 
Corporate         2018 Memebership   National                  $9,960.00
 Membership                           Association of
                                      Chain Drug
                                      Stores
 
Corporate         Annual Membership  Business Council          $3,000.00
 Membership                           of Alabama
 
Corporate         Corporate          US Pain                  $20,000.00
 Membership        Membership         Foundation Inc.
 
Corporate         Corporate          South Carolina            $3,000.00
 Membership        Membership         Alliance of
                                      Health Plans
 
Corporate         Corporate          The Oklahoma              $2,400.00
 Membership        Membership         State Chamber of
                                      Commerc
 
Corporate         Corporate          American                  $5,000.00
 Membership        Membership         Legislative
                                      Exchange Council
 
Corporate         Corporate          American                 $12,000.00
 Membership        Membership         Legislative
                                      Exchange Council
 
Corporate         Corporate          American Society         $20,000.00
 Membership        Membership         of Nephrology
 
Corporate         Corporate          American Society         $10,000.00
 Membership        Membership         of Nephrology
 
Corporate         Annual Membership  Iowa                      $2,000.00
 Membership        Dues               Biotechnology
                                      Association
 
Corporate         CHOT Annual        University of            $50,000.00
 Membership        Membership         Louisville
                                      School of Public
                                      Health
 
Corporate         Corporate          Maryland Health           $5,000.00
 Membership        Membership         Care Coalition
                                      DBA MidAtlantic
 
Corporate         Corporate          NCSL Foundation          $12,500.00
 Membership        Membership         for State
                                      Legislatures
 
Corporate         Corporate          Associated                $3,865.00
 Membership        Membership         Industries of
                                      Missouri
 
Corporate         Annual Associate   Derma Care Access       $100,000.00
 Membership        Membership         Network
 
Corporate         Corporate          Wisconsin                 $3,750.00
 Membership        Membership         Collaborative
                                      for Healthcare
                                      Quality
 
Corporate         Corporate          Academy of               $15,000.00
 Membership        Membership         Integrative Pain
                                      Management
 
Corporate         Corporate          Association of            $3,000.00
 Membership        Membership         Military
                                      Surgeons of the
                                      Unit
 
Corporate         DPAC Corporate     Diabetes Patient         $25,000.00
 Membership        Membership         Advocacy
                                      Coalition
 
Corporate         HISCI Membership   Health Industry           $5,300.00
 Membership                           Distributors
                                      Association
 
Corporate         CCCC Corporate     California                $5,000.00
 Membership        Membership         Chronic Care
                                      Coalition
 
Corporate         Corporate          America's                $25,000.00
 Membership        Membership 2018-   Physician Groups
                   2019
 
Corporate         Corporate          Integrated               $33,450.00
 Membership        Membership         Benefits
                                      Institute, Inc.
 
Corporate         Corporate          Integrated                $7,814.00
 Membership        Membership         Benefits
                                      Institute, Inc.
 
Corporate         Corporate          Integrated                $8,736.00
 Membership        Membership         Benefits
                                      Institute, Inc.
 
Corporate         2019 Affiliate     Greater                   $5,000.00
 Membership        Membership Dues    Philadelphia
                                      Business
                                      Coalition on
                                      Health
 
Corporate         Maryland Tech      Maryland Tech             $1,800.00
 Membership        Council            Council
                   Membership
 
Corporate         Gender Parity      Healthcare               $30,000.00
 Membership        Collaborative      Businesswomen's
                   Membership         Association
 
Donations         Adult Day Center   Visiting Nurse           $10,000.00
                   Expanded           Association of
                   Therapeutic        Somerset Hills
                   Programing
                   Request
 
Donations         SARP Program       The Pennsylvania        $150,000.00
                   Support            State University
 
Donations         Katy's Place       The Center For            $5,000.00
                   Child              Great
                   Development        Expectations
                   Center             Inc.
 
Donations         Community          Operation Jersey            $600.00
                   Outreach to        Cares
                   Veterans
 
Donations         Sanofi US          Seattle                   $5,000.00
                   Empowering Life    Children's
                   Photo Contest      Hospital
                                      Foundation
 
Donations         Student Support    Drexel University         $5,000.00
                   for Drexel
                   Chemical and
                   Biological
                   Engineering
 
Donations         XTL Youth          Affirmations              $2,500.00
                   Programming--Emp
                   owering Life
                   Winner
 
Donations         COTA for CJ T--    COTA Children's           $2,500.00
                   Empowering Life    Organ Transplant
                   Winner             Associati
 
Donations         General Mission    The Partnership          $10,000.00
                   Support            for Quality
                                      Medical Donati
 
Donations         Research Training  Trustees of The          $20,000.00
                   in                 University of
                   Pharmacoepidemio   Pennsylvania
                   logy
 
Donations         Friends of Cancer  Friends of Cancer        $50,000.00
                   Research Mission   Research
                   Support
 
Donations         Cooley Landing     Grassroots               $25,000.00
                   Community-Based    Ecology
                   Baylands
                   Restoration
                   Project
 
Donations         Green Printing     Arbor Day                 $4,944.00
                   Initiative         Foundation
 
Donations         Veterans and       U.S. Naval                $1,000.00
                   Careers            Academy Alumni
                                      Association
 
Donations         Fellowship         Pharmaceutical          $270,000.00
                   Support            Research and
                                      Manufacture
 
Donations         General Mission    United Way of                $55.00
                   Support            Northern New
                                      Jersey
 
Donations         2018 Warrior       Operation Warrior        $10,000.00
                   Wishes Program     Wishes
                                      Foundation
 
Donations         General Mission    ASTS Foundation          $50,000.00
                   Support
 
Donations         General Operating  American College          $2,500.00
                   Support            of Laboratory
                                      Animal Medicine
 
Donations         Meals on Wheels    Midland Adult             $5,000.00
                                      Services Inc.
 
Donations         General Operating  Washington Legal         $30,000.00
                   Support            Foundation
 
Donations         Empowering young   Junior                   $50,000.00
                   people for         Achievement of
                   success in STEM    New Jersey, Inc.
                   careers
 
Donations         Get Active and     College Diabetes         $12,000.00
                   Make a             Network Inc.
                   Difference
                   Challenge
 
Donations         Get Active and     Junior                    $2,500.00
                   Make a             Achievement USA
                   Difference
                   Challenge
 
Donations         Get Active & Make  Boys & Girls              $2,500.00
                   a Difference       Clubs of America
                   Challenge
 
Donations         Residential        Safe + Sound             $10,000.00
                   Children's         Somerset
                   Program
 
Donations         Get Active and     March of Dimes            $8,000.00
                   Make a             Foundation
                   Difference
                   Challenge
 
Donations         Healthy Food       The Salvation            $10,000.00
                   Pantry Program     Army
 
Donations         Responding to      Direct Relief            $25,000.00
                   California
                   Wildfires
 
Donations         Vets4Warrios       Rutgers                   $2,000.00
                                      University
                                      Foundation
 
Donations         MAP's Domestic     Map International        $10,000.00
                   Disaster Relief
                   Prepardness
 
Donations         Midland Explores   Midland Adult             $5,000.00
                   Community          Services Inc.
                   Program
 
Donations         MAS Employment     Midland Adult             $5,000.00
                   Program            Services Inc.
 
Donations         Get Active and     Wounded Warrior          $40,000.00
                   Make a             Project, Inc.
                   Difference
                   Challenge
 
Donations         Advancing          Students 2              $250,000.00
                   Authentic STEM     Science
                   Education
 
Donations         Success By 6 with  United Way of            $37,000.00
                   Scholarship        Northern New
                   Support and STEM   Jersey
                   Enhancement
 
Donations         Get Active and     National Alliance         $2,500.00
                   Make A             for Caregiving
                   Difference
                   Challenge
 
Donations         General Operating  Food Bank of             $25,000.00
                   Support            Somerset County
                                      Inc.
 
Donations         Corporate Work-    Cristo Rey Newark        $60,000.00
                   Study Program      High School
                                      Corp.
 
Donations         U.S. Disaster      Americares               $25,000.00
                   Assitance
 
Donations         LGBT Staff         Somerset Health           $7,000.00
                   Sensitivity        Care Foundation
                   Training
 
Donations         US Disaster        Heart To Heart           $25,000.00
                   Readiness &        International
                   Response           Inc.
 
Donations         U.S. Emergency     Direct Relief            $25,000.00
                   Preparedness and
                   Response
 
Donations         Empowering Inner   Sheltered Yoga            $5,000.00
                   City Kids
                   Through Yoga &
                   Meditation
 
Donations         Comprehensive      NJ Sharing                $5,000.00
                   Family Support     Network
                                      Foundation
 
Donations         NCCN Foundation    NCCN Foundation          $25,000.00
                   Patient Advocacy
                   Collaboration
 
Donations         Advocacy and       Deirdre O'Brien           $5,000.00
                   Forensic           Child Advocacy
                   Interviewing of    Center Inc.
                   Child Victims of
                   Abuse
 
Donations         Genearl Operating  Camp Quality USA         $10,000.00
                   Support            dba Camp Quality
                                      NJ
 
Donations         General Operating  Jersey Battered           $5,000.00
                                      Women's Service,
                                      Inc.
 
Donations         Trainee            Society for              $25,000.00
                   Professional       Neuroscience
                   Development
                   Awards
 
Donations         Project Self       Family Promise of        $10,000.00
                   Sufficiency--San   Monroe County
                   ofi in our
                   Communities
 
Donations         Americares         Americares                $5,000.00
                   Airlift Benefit
 
Donations         Get Active and     Dress for Success         $2,500.00
                   Make a             Northern New
                   Difference         Jersey--10
                   Challenge
 
Donations         Young Scholars     NJ SEEDS                 $10,000.00
                   Program
 
Donations         Vets4Warriors      Rutgers                  $10,000.00
                                      University
                                      Foundation
 
Donations         Foundations of     Dress for Success        $10,000.00
                   Success            Northern New
                                      Jersey--10
 
Donations         US Disaster        Heart To Heart           $25,000.00
                   Relief--Hurrican   International
                   e Michael          Inc.
 
Donations         Hurricane Michael  Direct Relief            $50,000.00
                   Response
 
Donations         Hunterdon County   Hunterdon                $10,000.00
                   Food Back Pack     Healthcare
                   Program            Foundation
 
Donations         General Operating  Hyacinth                 $10,000.00
                   Support            Foundation: A
                                      New Jersey
                                      Nonprofit
 
Donations         HSF General        Hispanic                  $5,000.00
                   Operating          Scholarship Fund
                   Support
 
Donations         Hurricane Michael  Americares               $25,000.00
                   Response
 
Donations         General Operating  Good Grief Inc.           $5,000.00
                   Support
 
Donations         General Operating  Deirdre O'Brien           $5,000.00
                   Support            Child Advocacy
                                      Center Inc.
 
Donations         Valhalla's Hope    Valhalla Veterans        $10,000.00
                                      Services
 
Donations         Residential        Community Hope,          $25,000.00
                   Recovery           Inc.
                   Programs for
                   Homeless
                   Veterans and Dis
 
Donations         Sanofi Corporate   Raritan Valley           $10,000.00
                   Mentor Program     Community
                   at RVCC            College Foundat
 
Donations         PRIDE Connect      Hyacinth                  $3,500.00
                   Project Support    Foundation: A
                                      New Jersey
                                      Nonprofit
 
Donations         Trevor's Life-     Trevor Project            $3,500.00
                   Saving Programs    Inc.
                   for LGBTQ Youth
 
Donations         General Operating  Junior                    $5,000.00
                   Support            Achievement of
                                      Northeastern
                                      Pennsylvania
 
Donations         Camp Nejeda:       Camp Nejeda              $10,000.00
                   Helping Kids       Foundation
                   with type 1
                   diabetes live
                   happier
 
Donations         Advocacy Program   Deirdre O'Brien           $5,000.00
                   for Child          Child Advocacy
                   Victims of Abuse   Center Inc.
                   and or Neglect
 
Donations         California         Direct Relief           $100,000.00
                   Wildfires
 
Donations         SP 2018 UW         United Way of            $86,982.00
                   Campaign Match     Monroe County
 
Donations         Vets4Warrios       Rutgers                   $4,000.00
                                      University
                                      Foundation
 
Donations         Support4Families:  Cancer Support           $15,000.00
                   Teens Connect      Community
                   School-Based       Central
                   Support Group
 
Donations         Supporting         Students 2               $25,000.00
                   Environmental      Science
                   Science for High
                   School Students
 
Donations         Health for         Covenant House           $25,000.00
                   Homeless Youth     New Jersey Inc.
 
Donations         Medical Home       Children's Health       $198,000.00
                   Initiative 2019    Fund
 
Donations         Serving Local      Matheny School           $10,000.00
                   Patients With      and Hospital
                   Disabilities       Inc.
 
Donations         Matheny School     Matheny School           $10,000.00
                   STEM program       and Hospital
                                      Inc.
 
Donations         Support4Families:  Cancer Support            $5,000.00
                   Strengthening      Community
                   Our Schools        Central
 
Donations         Food, Health and   The Community            $25,000.00
                   Hope: An Answer    Food Bank of New
                   to Diabetes (FHH   Jersey
                   Diabetes)
 
Donations         Camp Quality USA   Camp Quality USA         $10,000.00
                   dba Camp Quality   dba Camp Quality
                   NJ                 NJ
 
Donations         General Operating  Visiting Nurse           $10,000.00
                   Support            Association of
                                      Somerset Hills
 
Donations         Steeple Chase      Somerset Health         $100,000.00
                   Cancer Center      Care Foundation
                   Patient
                   Assistance Fund
 
Donations         General            Hyacinth                 $10,000.00
                   Operational        Foundation: A
                   Support            New Jersey
                                      Nonprofit
 
Donations         Healthier          Somerset Health          $10,000.00
                   Somerset           Care Foundation
 
Donations         HSF STEM Summit    Hispanic                 $50,000.00
                                      Scholarship Fund
 
Donations         Nights of Support  Good Grief Inc.          $10,000.00
                   Program
 
Donations         General Operating  Dress for Success        $10,000.00
                   Support            Northern New
                                      Jersey--10
 
Donations         Trevor's Life-     Boys & Girls             $10,000.00
                   Saving Programs    Clubs of Union
                   for LGBTQ Youth    County
 
Donations         Camp Nejeda:       Camp Nejeda              $10,000.00
                   Education and      Foundation
                   Empowerment for
                   Children
 
Donations         Vets4Warriors      Rutgers                  $10,000.00
                                      University
                                      Foundation
 
Donations         HSF Scholarship    Hispanic                 $50,000.00
                   Fund               Scholarship Fund
 
Donations         General Operating  NJ SEEDS                 $10,000.00
                   Support for NJ
                   SEEDS
 
Donations         Banco de           Banco de                 $25,000.00
                   ALimentos de       Alimentos de
                   Puerto Rico        Puerto Rico
 
LOR               BCCNS Patient      BCCNS Alliance           $25,000.00
                   Project
 
LOR               Patient            Patients Rising,         $10,000.00
                   Engagement         Inc.
                   Sponsorship
 
LOR               Patient Education  Taking Control of        $40,000.00
                   Diabetes           Your Diabetes
                   Conferences and
                   Health Fairs
 
LOR               Biological         California               $15,000.00
                   Research           Institute of
                   Symposium          Technology
 
LOR               Patient Skin       American Cancer         $200,000.00
                   Cancer Education   Society
                   and Awareness
 
LOR               Populatoin Health  Thomas Jefferson         $60,000.00
                   Leadership         University
                   Series
 
LOR               nPOD Annual        University of            $15,000.00
                   Meeting            Florida
 
LOR               Diabetes Scholars  Diabetes Scholars        $10,000.00
                   Foundation         Foundation
                   College
                   Scholarships
 
LOR               2018 Annual        Health Action             $4,700.00
                   Symposium and      Council
                   Conference
 
LOR               Western Atrial     University of            $50,000.00
                   Fibrillation       Utah
                   Symposium 2018
 
LOR               Gordon Research    Gordon Research           $5,000.00
                   Conference on      Conferences
                   Myelin
 
LOR               Cell Culture       Engineering               $5,000.00
                   Engineering XVI    Conferences
                   Conference         International
 
LOR               2018 Alliance      Alliance for             $20,000.00
                   Industry Summitt   Continuing
                                      Education in the
                                      Health Sciences
 
LOR               Symposium on Drug  Massachusetts             $8,000.00
                   Delivery Systems   Institute of
                                      Technology
 
LOR               2nd Annual EPIC    Children's               $10,000.00
                   Diabetes           Diabetes
                   Conference         Foundation
 
LOR               ASN 48th Annual    American Society          $2,500.00
                   Meeting            for
                                      Neurochemistry
 
LOR               2018 BIO           Biotechnology           $334,500.00
                   International      Innovation
                   Convention         Organization
 
LOR               FOCIS 2018 Annual  Federation of            $25,000.00
                   Meeting            Clinical
                                      Immunology
                                      Societies
 
LOR               2018 BIO Europe    Biotechnology            $22,500.00
                   Spring             Innovation
                                      Organization
 
LOR               2018 BIO Europe    Biotechnology            $22,500.00
                   Fall               Innovation
                                      Organization
 
LOR               Annual Healthcare  MIT Sloan                 $5,000.00
                   Conference         Healthcare
                                      Conference and
                                      Club
 
LOR               SOT 2018 Annual    Society of               $10,000.00
                   Meeting            Toxicology
 
LOR               2018 Public        American                 $20,000.00
                   Policy Forum       Association of
                                      Diabetes
                                      Educator
 
LOR               Annual Gala        Asian American           $20,000.00
                   Dinner             Legal Defense
                                      and Educatio
 
LOR               JDRF Imagine Gala  JDRF                     $10,000.00
 
LOR               2018 Advocacy      Research!America         $25,000.00
                   Awards Dinner
 
LOR               JDRF Government    JDRF                     $50,000.00
                   Day                International
 
LOR               Immune Tolerance   Parker Institute         $10,000.00
                   Symposium          for Cancer
                                      Immunotherapy
 
LOR               Annual Forum on    National Academy         $85,000.00
                   Drug Discovery     of Sciences
                   and Development
 
LOR               Biomedical         Foundation for           $25,000.00
                   Research Program   Biomedical
                                      Research
 
LOR               Annual Symposium   CASSS                     $2,500.00
                   of Regulatory
                   and Analytical
                   Science
 
LOR               Analytical         CASSS                     $2,500.00
                   Technologies
                   Symposium
 
LOR               2018 Gordon        Gordon Research           $3,000.00
                   Research           Conferences
                   Conference on
                   Medicinal
                   Chemistry
 
LOR               2018 AMSSM         American Medical         $50,000.00
                   Foundation         Society for
                   Research Grant     Sports Medicine
                   Award Program
 
LOR               Patient            National Health         $130,000.00
                   Perspective        Council
                   Program
 
LOR               Annual Business    Waltham Chamber           $6,000.00
                   Meeting            of Commerce
 
LOR               Barriers of the    Gordon Research           $5,000.00
                   CNS Conference     Conferences
 
LOR               FARE Patient       Food Allergy             $50,000.00
                   Registry           Research &
                                      Education, Inc.
 
LOR               Wonder Women:      Center for Talent        $40,000.00
                   Flourishing and    Innovation
                   Thriving on the
                   Frontiers
 
LOR               Early              American                 $55,000.00
                   Osteoarthritis     Orthopaedic
                   and Prevention     Society for
                   of OA              Sports Medicine
                   Progression
 
LOR               Pharmacy           Iowa Pharmacy            $10,000.00
                   Leadership         Association
                   Training Program   Foundation
 
LOR               FIU Global Health  Florida                  $95,000.00
                   Conference         International
                                      University Board
                                      of Trustees
 
LOR               2018 Statewide     Florida Health           $15,000.00
                   Cardiac            Care Coalition
                   Collaborative
 
LOR               36 Annual JDRF     JDRF                      $2,500.00
                   Boston Gala        International
 
LOR               Innovative         Preventive              $150,000.00
                   Medicine           Cardiovascular
                   Campaign           Nurses
                                      Association
 
LOR               Women and Heart    WomenHeart: The          $50,000.00
                   Disease Program    National
                                      Coalition for
                                      Women With Heart
                                      Disease
 
LOR               Off to College     College Diabetes         $50,000.00
                   Sponsorship 2018   Network Inc.
 
LOR               Patient Education  Diabetes                  $2,000.00
                   Diabetes           Foundation of
                   Conference         Mississippi
 
LOR               Division of        ACS Division of           $3,000.00
                   Medicinal          Medicinal
                   Chemistry          Chemistry
                   Program ACS
                   National Meeting
 
LOR               Patient Centered   National Lipid           $16,060.00
                   Management of      Association
                   Dyslipidemia
 
LOR               2018 Annual SMA    Families of SMA           $5,000.00
                   Conference         DBA Cure SMA
 
LOR               2018 ZERO          ZERO--The End of          $2,000.00
                   Prostate Cancer    Prostate Cancer
                   Summit
 
LOR               DA4S West Coast    Diversity                 $3,000.00
                   2018               Alliance for
                                      Science, Inc.
 
LOR               Economic           Greater New               $4,000.00
                   Development =      England Minority
                   Corporate          Supplier
                   Sponsorship        Development
                   Renewal
 
LOR               2018 V-BID         Regents of the           $50,000.00
                   Summit: V-BID at   University of
                   the Big House      Michigan
 
LOR               AUTM 2018 Annual   Association of            $5,000.00
                   Meeting            University
                                      Technology Mana
 
LOR               2018 Annual        BIONJ Inc.               $10,000.00
                   Dinner Meeting
 
LOR               SOT Annual         Society of                $2,500.00
                   meeting            Toxicology
 
LOR               Forum Group on     George Washington        $70,000.00
                   Arbovirus          University
                   Infections
 
LOR               World Vitiligo     The Umass                 $2,500.00
                   Day 2018           Memorial
                   Conference         Foundation Inc.
 
LOR               Men's Health       Men's Health             $30,000.00
                   Month              Network
                   Sponsorship
 
LOR               OSU Pharmacy       Oregon State              $7,500.00
                   Partners Program   University
                                      Foundation
 
LOR               2018 Global        International             $5,000.00
                   Doctoral           Biomedical
                   Partnerships       Research
                   Annual Workshop    Alliance
 
LOR               2018 AAAS Annual   American                 $25,000.00
                   Meeting            Association for
                   Sponsorship        the Advancement
 
LOR               Cold Spring        Cold Spring              $15,000.00
                   Harbor Meetings    Harbor
                   and Courses        Laboratory
                   Program
 
LOR               2018 Annual Event  New York & New           $10,000.00
                   Sponsorship        Jersey Minority
                                      Supplier
                                      Development
 
LOR               2018 Greater New   American Diabetes        $10,000.00
                   York Tour de       Association
                   Cure & Wellness
                   Expo
 
LOR               National Minority  Make Well Known          $25,000.00
                   Cardiovascular     Foundation
                   Alliance
 
LOR               OASC Annual        Ohio Association          $1,000.00
                   Conference         of Senior
                                      Centers
 
LOR               2018 Flu Podcast   Women In                  $5,000.00
                   Campaign           Government
                                      Foundation, Inc.
 
LOR               25th Annual        Florida Health            $5,000.00
                   National           Care Coalition
                   Conference
 
LOR               State Lung Health  Respiratory                 $500.00
                   Education          Health
                   Program            Association
 
LOR               CWAG 2018 Annual   Conference of             $5,000.00
                   Meeting            Western
                                      Attorneys
                                      General
 
LOR               2018 Town Hall     American Society        $203,900.00
                   Meeting Support    for Preventive
                                      Cardiology
 
LOR               Get in Rhythm      American                 $25,000.00
                   Stay in Rhythm--   Foundation for
                   Afib Patient       Women's Health
                   Conference
 
LOR               PRISMS 10th Smith- PRISMS, Inc.              $2,500.00
                   Magenis Syndrome
                   Conference
 
LOR               Guidelines for     Florida                  $50,000.00
                   Antimicrobial      International
                   Stewardship        University
                                      Foundation
 
LOR               Latin American     Florida                  $70,000.00
                   and Caribbean      International
                   Diabetes           University
                   Network: A         Foundation
                   framework
 
LOR               Assesment of       Florida                  $60,000.00
                   acellular          International
                   vaccination        University
                   programs in        Foundation
                   Mexico, Costa
 
LOR               Bioorganic         Gordon Research           $1,000.00
                   Research           Conferences
                   Conference
 
LOR               National           Trustees of             $150,000.00
                   Community Health   Boston
                   Workers Project    University
 
LOR               Health Innovation  Springboard 2000         $25,000.00
                   Hub 2018           Enterprises,
                                      Inc.
 
LOR               Bill Foege Event   Map International        $10,000.00
                   Sponsorship
 
LOR               SDHB Pheo-Para     SDHB Pheo-Para           $10,000.00
                   Coalition Gala     Coalition, Inc.
 
LOR               9th International  University of             $2,000.00
                   Conference on      Florida
                   Unstable           Foundation, Inc.
                   Microsatellites
                   and Human
                   Disease
 
LOR               21st Annual        HealthCare 21             $3,000.00
                   Health &           Business
                   Productivity       Coalition
                   Forum
 
LOR               2018 Celebrating   Blood and Marrow         $25,000.00
                   a Second Chance    Transplant
                   at Life            Information
                   Survivorship
                   Sympos
 
LOR               Patient Education  Taking Control of        $40,000.00
                   Diabetes           Your Diabetes
                   Conferences and
                   Health Fairs
 
LOR               Patient Education  Taking Control of        $60,000.00
                   Diabetes           Your Diabetes
                   Conferences and
                   Health Fairs
 
LOR               2018 FH Global     The FH Foundation        $75,000.00
                   Summit
 
LOR               Chemical Biology   Northeastern              $1,000.00
                   in the Hub         Section of the
                   Symposium          American
                                      Chemical Society
 
LOR               2018 Champion of   National Kidney           $1,000.00
                   Hope Tribute       Foundation of
                   Dinner             Michigan
 
LOR               7th International  CASSS                     $2,500.00
                   Symposium on
                   Higher Order
                   Structure of
                   Protein
                   Therapeutics
 
LOR               Bioassays 2018:    CASSS                     $2,500.00
                   Scientific
                   Approaches &
                   Regulatory
                   Strategies
 
LOR               A Taste of Ginger  Joslin Diabetes          $10,000.00
                   Gala               Center, Inc.
 
LOR               2018 Annual        Western                  $10,000.00
                   Meeting            Governors'
                   Sponsorship        Foundation
 
LOR               Community Hope     Community Hope,          $10,000.00
                   Annual Dinner      Inc.
 
LOR               8th International  Florida                 $150,000.00
                   Conference on      International
                   Global Health      University
                                      Foundation
 
LOR               8th International  Florida                  $14,000.00
                   Conference on      International
                   Global Health      University
                                      Foundation
 
LOR               2018 Machestic     Machestic Dragons         $5,500.00
                   Dragons ``Paddle
                   for Pink''
                   Community Dragon
 
LOR               ``Visions of       Diabetes                  $2,500.00
                   Hope'' Awards      Foundation Inc.
                   Dinner
 
LOR               Stick It to        Mercy Health              $2,000.00
                   Diabetes           Foundation
                                      Joplin
 
LOR               2018               FSH Society               $2,000.00
                   International
                   Research
                   Conference
 
LOR               Teratology         Teratology                $1,500.00
                   Society 58th       Society
                   Annual Meeting
 
LOR               255th ACS          ACS Division of           $5,000.00
                   National Meeting   Biochemical
                   and Exposition     Technology
                   (BIOT Division)
 
LOR               Forum on           National Academy         $50,000.00
                   Neuroscience and   of Sciences
                   Nervous System
                   Disorders
 
LOR               2018 National      ACS Division of           $3,000.00
                   Medicinal          Medicinal
                   Chemistry          Chemistry
                   Symposium
 
LOR               Giving Diabetes    The Diabetes              $2,500.00
                   the Blues          Coalition of
                   Conference         Mississippi
 
LOR               Diabetes Care and  Academy of               $10,000.00
                   Dietetic           Nutrition and
                   Education          Dietetics
                   Program
 
LOR               2018 Heart &       The American             $25,000.00
                   Stroke Ball        Heart
                                      Association
 
LOR               RNA Therapeutics:  The Umass                $10,000.00
                   From Base Pairs    Memorial
                   to Bedsides        Foundation Inc.
 
LOR               2nd Annual Heart   Metabolic               $100,000.00
                   in Diabetes--HiD   Endocrine
                                      Education
                                      Foundation
 
LOR               Immuno-Therapy     The University of        $50,000.00
                   Scientific         Texas Foundation
                   Workshop
 
LOR               Cell Culture       Engineering               $2,500.00
                   Engineering XVI    Conferences
                   Conference         International
 
LOR               2018 LVBCH Annual  Lehigh Valley             $1,000.00
                   Conference         Business
                                      Coalition on
                                      Healthcare
 
LOR               Bowhay Institute   The Council of            $5,000.00
                                      State
                                      Government, Ltd.
 
LOR               2018 Lysosomes     Gordon Research           $2,000.00
                   and Endocytosis    Conferences
                   Gordon Research
                   Conference
 
LOR               South Sound JDRF   JDRF                      $1,000.00
                   One Walk           International--N
                                      orthwest Chapter
 
LOR               36th Annual        JDRF                      $2,500.00
                   Nordstrom Beat
                   the Bridge
 
LOR               Diabetes Under     American Diabetes         $1,000.00
                   the Dome Event     Association
 
LOR               2018 Wenger        WomenHeart: The          $25,000.00
                   Awards Dinner      National
                                      Coalition for
                                      Women With Heart
                                      Disease
 
LOR               CRI's              Cancer Research          $25,000.00
                   Immunotherapy      Institute Inc.
                   Patient Summit
                   Series
 
LOR               2018 HBA Woman of  Healthcare               $15,000.00
                   the Year Event     Businesswomen's
                                      Association
 
LOR               Transforming       Dress for Success        $15,000.00
                   Lives 20th year    Northern New
                   Celebration        Jersey--10
 
LOR               Recovery of        American Chemical        $10,000.00
                   Biological         Society,
                   Products XVIII     Division of
                   Conference         Biochemistry
 
LOR               Friends for Life   Children with            $25,000.00
                   Orlando 2018       Diabetes
                   Patient
                   Conference
 
LOR               2018 Orlando       Children with            $10,000.00
                   Fellows Program    Diabetes
 
LOR               Hypoglycemia       Endocrine Society       $150,000.00
                   Quality
                   Improvement/
                   Prevention
                   Project
 
LOR               2018 Annual Henry  The Henry Kunkel          $2,000.00
                   Kunkel Society     Society c/o The
                   Meeting            Rockefeller
 
LOR               GPEN 2018          Globalization of          $1,500.00
                   Scientific         Pharmaceutics
                   Meeting            Education
 
LOR               2018 Conference    Employers Health          $7,500.00
                   Sponsorship        Coalition, Inc.
 
LOR               RVCC's 50th        Raritan Valley           $25,000.00
                   Anniversary        Community
                   Golden Harvest     College Foundat
                   Gala
 
LOR               2018 PQA Annual    Healthcare                $6,100.00
                   Meeting            Businesswomen's
                                      Association
 
LOR               2018 PQA Annual    PQA, Inc.                $12,500.00
                   Meeting
 
LOR               eValue8 Project    Northeast                 $2,500.00
                                      Business Group
                                      on Health
 
LOR               Annual Good Grief  Good Grief Inc.           $3,500.00
                   Gala
 
LOR               8th Annual         Center for               $10,000.00
                   Diversity,         Healthcare
                   Inclusion, &       Innovation
                   Health Equity
                   Symposium
 
LOR               Real World         American Diabetes       $210,000.00
                   Evidence           Association
                   Generation and
                   Analysis
                   Research
                   Symposium
 
LOR               From Rare to       Keystone Symposia         $3,000.00
                   Care: Discovery,   on Molecular and
                   Modeling and       Cellular
                   Translation of
                   Rare Diseases
 
LOR               6th Annual         International            $15,000.00
                   Meeting of the     Cytokine and
                   International      Interferon
                   Cytokine &         Society
                   Interferon
 
LOR               Diabetes and CV    Icahn School of          $30,000.00
                   Risk Factors       Medicine at
                   Program            Mount Sinai
 
LOR               Prix Galien USA    The Galien               $15,000.00
                   Forum              Foundation
 
LOR               Learning Sessions  The Health                $5,000.00
                   Program            Collaborative
 
LOR               Horton's Kids      Horton's Kids,           $15,000.00
                   Comprehensive      Inc.
                   Programming for
                   At-Risk Children
 
LOR               Children's Health  Children's Health        $30,000.00
                   Fund 2018 Annual   Fund
                   Benefit
 
LOR               60th Anniversary   Project Hope The         $10,000.00
                   Project HOPE       People To People
                   Gala               Health
 
LOR               Structural         Harvard Medical           $2,500.00
                   Biology Meeting    School
 
LOR               PROMIS: Global     Harvard Medical           $2,500.00
                   Advances in        School
                   Methodology and
                   Clinical Science
 
LOR               68th Annual        Somerset County           $2,500.00
                   Outstanding        Business
                   Citizen of the     Partnership
                   Year Awards
                   Dinner
 
LOR               Annual Meeting     Somerset County           $2,500.00
                   Awards Luncheon    Business
                   2018               Partnership
 
LOR               Illinois Diabetes  Illinois Diabetes           $250.00
                   Caucus             Caucus
                   Fundraiser         Foundation
 
LOR               18th annual        The Virginia                $700.00
                   luncheon           Public Access
                                      Project
 
LOR               Grand Tastings     Jersey Battered          $15,000.00
                   XXIV               Women's Service,
                                      Inc.
 
LOR               d18 Executive      The diaTribe            $250,000.00
                   Innovation Lab     Foundation
                   on Diabetes and
                   Prediabetes
 
LOR               2018 Scientific    Children's               $10,000.00
                   Program in         Hospital
                   Cellular and       Corporation
                   Molecular
                   Medicine
 
LOR               JDRF One Walk,     JDRF                      $2,500.00
                   Washington, DC
 
LOR               WOCIP 2018-2019    Women of Color in        $20,000.00
                   Annual Meeting     Pharma
 
LOR               WOCIP 2018-2019    Women of Color in        $20,000.00
                   Annual Meeting     Pharma
 
LOR               Koch Institute     Massachusetts             $5,000.00
                   2018 Summer        Institute of
                   Symposium          Technology
 
LOR               Koch Institute     Massachusetts             $5,000.00
                   2018 Summer        Institute of
                   Symposium          Technology
 
LOR               Event Sponsorship- Discovering              $10,000.00
                   Discovering        Justice
                   Justice 20th
                   Anniversary Gala
 
LOR               Boston             Children's                $3,000.00
                   Postdoctoral       Hospital
                   Association        Corporation
                   Symposium on
                   Careers and
                   Collaboration in
                   Science
 
LOR               ONE: The Ultimate  Taking Control of        $20,000.00
                   Conference for     Your Diabetes
                   Adult Type 1
 
LOR               2018 Gordon        Gordon Research           $3,000.00
                   Research           Conferences
                   Conference on
                   Heterocycles
 
LOR               PDAF Fundraiser    Prescription Drug         $1,250.00
                   Sponsorship        Assistance
                                      Foundation
 
LOR               Generations Gala   Adult Day Center          $3,000.00
                   Event              of Somerset
                                      County
 
LOR               12th Annual        The diaTribe             $10,000.00
                   Diabetes Forum     Foundation
 
LOR               2018 Triangle      JDRF                     $10,000.00
                   Hope Glala
 
LOR               Lecture Series     The New York             $25,000.00
                   Program            Academy of
                                      Sciences
 
LOR               Division of        ACS Division of           $3,000.00
                   Medicinal          Medicinal
                   Chemistry          Chemistry
                   Program ACS
                   National Meeting
 
LOR               11th Annual        Brigham and               $2,000.00
                   Polycystic         Women's Hospital
                   Kidney Disease
                   Symposium
 
LOR               DA4S East Coast    Diversity                 $7,500.00
                   2018               Alliance for
                                      Science, Inc.
 
LOR               The Jessica        Dana Farber               $5,000.00
                   Ingram Lecture     Cancer Institute
                   Series
 
LOR               The Jessica        Dana Farber               $5,000.00
                   Ingram Lecture     Cancer Institute
                   Series
 
LOR               Key Initiatives    Prostate Cancer          $30,000.00
                   Program            Education
                                      Council
 
LOR               NEQCA Annual       New England               $5,000.00
                   Forum              Quality Care
                                      Alliance
 
LOR               MMRF 2018 Myeloma  Multiple Myeloma        $100,000.00
                   Patient and        Research
                   Caregiver          Foundation
                   Education
                   Program
 
LOR               National Forum     National Forum          $200,000.00
                   for Heart          for Heart
                   Disease            Disease and
                                      Stroke
 
LOR               TB Survivors for   National TB               $5,000.00
                   Patient            Controllers
                   Education          Association
 
LOR               9th Annual Spirit  Association of           $50,000.00
                   of the Heart       Black
                   Awards Dinner      Cardiologists
 
LOR               Change for Women   Catalyst Inc.            $15,000.00
                   in the Workplace
                   Program
 
LOR               2018 Annual        Washington Policy         $3,500.00
                   Dinner             Center
 
LOR               National           The Mended               $25,000.00
                   Education &        Hearts, Inc.
                   Training
                   Conference 2018
 
LOR               2018 ICSA          International             $3,000.00
                   Symposium          Chinese
                                      Statistical
                                      Association
 
LOR               BMT InfoNet        Blood and Marrow         $10,000.00
                   Patient Guide      Transplant
                   Reprint            Information
 
LOR               Research on        Harvard T.H. Chan       $200,000.00
                   Health             School of Public
                   Technology         Health
                   Assessment
 
LOR               DIA Inspires       Drug Information          $4,500.00
                   Award Dinner       Asssociation
                                      (DIA)
 
LOR               Diabetes           Fundacion Centro          $7,000.00
                   Education          Pediatrico de
                   Program for        Diabetes
                   School Personnel
                   and T1D Students
 
LOR               NCCN Guidelines    NCCN Foundation          $25,000.00
                   for Patients
                   guide
 
LOR               Fall Meeting       Middle Atlantic           $1,000.00
                   Sponsorship        Reproduction and
                                      Teratolog
 
LOR               PROMIS: Global     PROMIS Health            $15,000.00
                   Advances in        Organization
                   Methodology and    (PHO)
                   Clinical Science
 
LOR               Immunization       Idaho                     $2,500.00
                   Summit 2018        Immunization
                                      Coalition
 
LOR               Bob Langer 70th    Rutgers                  $20,000.00
                   Birthday Gala      University
                   and Symposium      Foundation
 
LOR               TMA Group Annual   Texas Medical             $1,200.00
                   Meeting            Association
 
LOR               Clinical Inertia   American Diabetes       $300,000.00
                   Campaign           Association
 
LOR               Life Sciences      Life Sciences PA            $250.00
                   Event June 2018
 
LOR               CE in the          CASSS                     $2,500.00
                   Biotechnology &
                   Pharmaceutical
                   Industries: 20th
                   Symposium
 
LOR               15th Symposium on  CASSS                     $2,500.00
                   the Practical
                   Applications of
                   Mass
                   Spectrometry
 
LOR               NCQA's Quality     National                 $10,000.00
                   Talks 2018         Committee for
                                      Quality
                                      Assurance
 
LOR               Gala of Giving     Operation Jersey          $3,000.00
                   Country Style      Cares
                   2018
 
LOR               Cell & Gene        CASSS                     $5,000.00
                   Therapy Products
                   (CGTP):
                   Manufacturing,
                   Quality
 
LOR               Newletter Funding  Skin Cancer             $100,000.00
                                      Foundation
 
LOR               Advocating for     Lupus Foundation          $5,000.00
                   Chronic Disease    of America Inc.
                   Patients
 
LOR               Inspiring Hope     Cancer Support            $2,500.00
                   Gala               Community
                                      Central
 
LOR               2018 National      Lung Cancer              $10,000.00
                   Advocacy Summit    Alliance
 
LOR               Bastille Day       Resources USA             $5,000.00
                   Boston 2018        Inc.
 
LOR               Bastille Day       Resources USA            $10,000.00
                   Washington DC      Inc.
                   2018
 
LOR               The Lancet Women   Icahn School of         $100,000.00
                   and                Medicine at
                   Cardiovascular     Mount Sinai
                   Disease
                   Commission
 
LOR               Northeast          CASSS                     $2,500.00
                   Regional Forum
                   October 2018
 
LOR               2018 National      Research!America         $25,000.00
                   Health Research
                   Forum
 
LOR               Promoting Nurses   Preventive               $25,000.00
                   as Leaders in      Cardiovascular
                   Prevention         Nurses
                   Program            Association
 
LOR               ACCC educational   Association of          $144,000.00
                   program funding    Community Cancer
                                      Centers
 
LOR               Patient Access     Alliance for             $75,000.00
                   Collaborative      Patient Access
 
LOR               NJMLA 2018 Annual  New Jersey Muslim         $1,250.00
                   Eid Gala           Lawyer
                                      Association
 
LOR               2018 Biomarkers    Foundation for            $2,500.00
                   Consortium         the National
                   meeting            Institutes of
                                      Health
 
LOR               Pro Bono           Pro Bono                 $25,000.00
                   Partnership 2018   Partnership
                   Gala
 
LOR               Tour de Cure       American Diabetes         $2,500.00
                   Hawaii             Association
 
LOR               19th Annual        Patient Advocate         $10,000.00
                   Patient Congress   Foundation
 
LOR               Patient Education  ZERO--The End of          $8,000.00
                   Webinar Funding    Prostate Cancer
 
LOR               2018 Diabetes      Joslin Diabetes           $5,000.00
                   Coalition          Center, Inc.
                   Conference
 
LOR               Mary's Center      Mary's Center            $30,000.00
                   2018 Symposium
 
LOR               2018 Safety        Safety                    $2,500.00
                   Pharmacology       Pharmacology
                   Society Annual     Society
                   meeting
 
LOR               Drugs for          Drugs for                $50,000.00
                   Neglected          Neglected
                   Diseases           Diseases
                   initiative         Initiative,
                   (DNDi)'s Making    North American
                   Medical History    Inc.
 
LOR               Drugs for          Drugs for                $25,000.00
                   Neglected          Neglected
                   Diseases           Diseases
                   initiative         Initiative North
                   (DNDi)'s Making    American Inc.
                   Medical History
 
LOR               Drugs for          Drugs for                $25,000.00
                   Neglected          Neglected
                   Diseases           Diseases
                   initiative         Initiative North
                   (DNDi)'s Making    American Inc.
                   Medical History
 
LOR               Pharmacy Alumni    The Ohio State            $1,000.00
                   Society            University
                   Pharmathon 5k      Foundation
                   Sponsorship
 
LOR               Diabetes Policy    Alliance for            $150,000.00
                   Advocacy           Patient Access
                   Initiatives
 
LOR               Yale               Yale University           $2,000.00
                   Immunobiology
                   Student
                   Symposium 2018
 
LOR               ConnecT1D Family   ConnecT1D                 $5,000.00
                   Camp 2018
 
LOR               2018 Alumni Hall   Hispanic                 $25,000.00
                   of Fame Gala       Scholarship Fund
                   Dinner
 
LOR               JDRF One Walk      JDRF                      $5,000.00
 
LOR               ACS CAN National   American Cancer          $35,000.00
                   Advocacy           Society Cancer
                   Activities         Action Network
 
LOR               American College   American College          $2,500.00
                   of Toxicology      of Toxicology
                   39th Annual
                   Meeting
 
LOR               Fall Advocacy Day  ASTS Foundation          $15,000.00
 
LOR               2018 OFII Annual   Organization for         $15,000.00
                   Dinner             International
                                      Investment
 
LOR               2018 Patient &     Biotechnology            $10,000.00
                   Health Advocacy    Innovation
                   Summit             Organization
 
LOR               2018 Indiana Tour  American Diabetes         $2,500.00
                   de Cure            Association,
                                      Indiana
 
LOR               2018 JDRF One      JDRF                      $5,000.00
                   Walk Syracuse      International
 
LOR               12th Annual Gala   International            $10,000.00
                   Celebration        Myeloma
                                      Foundation
 
LOR               14th Annual        National Alliance         $2,500.00
                   Meeting of         of State
                   NASPCC             Prostate Cancer
 
LOR               Translational      American                 $25,000.00
                   Cancer Research    Association for
                   for Basic          Cancer Research
                   Scientists
                   Workshop
 
LOR               Boston Heart Walk  American Heart            $5,000.00
                                      Association
 
LOR               JDRF One Walk      JDRF                      $5,000.00
                   2018               International
 
LOR               Airline Benefit    Americares               $12,000.00
                   Gala
 
LOR               Improving          National Minority       $125,000.00
                   Diabetes and       Quality Forum
                   Cardiovasular
                   Disease
                   Management
 
LOR               Digital Health     MassChallenge,          $100,000.00
                   Accellerator       Inc.
                   Program
 
LOR               Multiple Myeloma   Blood and Marrow          $3,750.00
                   Patient Survival   Transplant
                   Guide              Information
 
LOR               2018 ACS CAN       American Cancer          $25,000.00
                   State Events       Society Cancer
                   Program            Action Network
 
LOR               Healthcare         American College          $1,000.00
                   Leaders            of Healthcare
                   Educational        Executives
                   Events
 
LOR               36th Annual        President and            $10,000.00
                   Retreat for the    Fellows of
                   Harvard/MIT MD-    Harvard College
                   PhD Program
 
LOR               Moving the Needle  Healthcare                $1,000.00
                   on Gender Parity   Businesswomen's
                                      Association
 
LOR               Employer's Guide   Northeast                $17,500.00
                   to Digital         Business Group
                   Diabetes           on Health
                   Prevention and
                   Management
 
LOR               10th Annual        Prevent Cancer            $5,000.00
                   Health Fair and    Foundation
                   5k Walk/Run
 
LOR               16th Annual Gala   Fundacion Centro          $3,500.00
                   Dinner             Pediatrico de
                                      Diabetes
 
LOR               Advancement and    Cross-Company             $2,500.00
                   Challenges         Abuse Liability
                   Meeting            Council
 
LOR               Respiraory         Alliance for             $50,000.00
                   Therapy Access     Patient Access
                   Working Group
 
LOR               The Champions For  Skin Cancer              $25,000.00
                   Change Gala        Foundation
 
LOR               High Hopes Gala    Joslin Diabetes          $25,000.00
                                      Center, Inc.
 
LOR               Friends Annual     Friends of Cancer        $10,000.00
                   Cancer Research    Research
                   Leadership
                   Awards
 
LOR               Women Building     Virginia Bio              $3,000.00
                   Bio Sponsorship
 
LOR               NACHW              Trustees of              $20,000.00
                   Organizational     Boston
                   Launch             University
                   Announcement
                   Event
 
LOR               2018 PQA           PQA, Inc.                 $7,500.00
                   Leadership
                   Summit
 
LOR               High Level         Speak Up Africa d/       $25,000.00
                   Conference and     b/a The Access
                   Awards Event       Challenge
 
LOR               International      International            $90,000.00
                   Myeloma            Myeloma
                   Foundation         Foundation
                   Patient
                   Initiative
                   Programs
 
LOR               NCCN Innovation    National                 $40,000.00
                   Pilot Program      Comprehensive
                                      Cancer Network
 
LOR               Annual AMCP        Academy of               $18,000.00
                   meeting            Managed Care
                                      Pharmacy
 
LOR               Solvable Problems  The diaTribe             $48,000.00
                   in Diabetes        Foundation
                   Program
 
LOR               NESOT Annual       Society of                $1,500.00
                   Meeting            Toxicology
 
LOR               Patient Advocacy   Cancer Support           $75,000.00
                   Kit for Multiple   Community
                   Myeloma
 
LOR               Patient Education  National Kidney           $7,500.00
                   Brochure Big Ask   Foundation, Inc.
                   Big Give
 
LOR               Patient Awareness  National Hispanic        $25,000.00
                   and Education      Medical
                   Program for        Association
                   Hispanic Patient
 
LOR               Diabetes Family    Fundacion Centro          $5,000.00
                   Day Sponsorship    Pediatrico de
                                      Diabetes
 
LOR               Annual Promise     JDRF                     $20,000.00
                   Ball               International
 
LOR               Congress           American Society         $10,000.00
                   Sponsorship        of Hematology
 
LOR               Scientific Annual  Lupus Research           $10,000.00
                   Conference         Alliance
 
LOR               R3 Annual Forum    Multi Regional            $7,500.00
                                      Clinical Trial
                                      Center of
                                      Brigham
 
LOR               Diabetes           Public Health            $10,000.00
                   Prevention on      Advocates
                   the Ground in
                   California
                   Sponsorship
 
LOR               Northcrest Annual  NorthCrest                $2,500.00
                   Gala               Medical Center
                                      Foundation
 
LOR               19th Annual        GLBTQ Legal               $3,000.00
                   Spirit of          Advocates &
                   Justice Award      Defenders (GLAD)
                   Dinner
 
LOR               AUTM Annual        Association of            $5,000.00
                   Meeting            University
                                      Technology Mana
 
LOR               TCYOD Patient      Taking Control of        $75,000.00
                   Conferences and    Your Diabetes
                   Health Fairs
 
LOR               New Jersey Smart   RideWise, Inc.            $1,000.00
                   Workplace Annual
                   recognition
                   event
 
LOR               Breakfast          Women In                  $7,500.00
                   Sponsorship        Government
                                      Foundation, Inc.
 
LOR               Patient Education  Malecare                 $20,000.00
                   African American
                   Men with
                   Prostate Cancer
 
LOR               Patient Education  Malecare                 $15,000.00
                   Brochure: Simple
                   Cancer
 
LOR               ONE: The           Taking Control of        $75,000.00
                   Ultimaite          Your Diabetes
                   Conference and
                   Retreate for
                   Adults with Type
                   I
 
LOR               Women in           All in Together          $40,000.00
                   Healthcare         Campaign Inc.
                   Policy Forum
 
LOR               Innovation Labs    The diaTribe            $100,000.00
                   on Diabetes and    Foundation
                   Prediabetes
 
LOR               Annual Joe         Joe Andruzzi              $5,000.00
                   Andruzzi           Foundation Inc.
                   Foundation Gala
 
LOR               Corporate          AMGA                     $25,000.00
                   Sponsorship for
                   Institute for
                   Quality
                   Leadership
 
LOR               Patient Awareness  ZERO--The End of         $10,000.00
                   and Education      Prostate Cancer
                   Program
 
LOR               Congress           Metabolic                $50,000.00
                   Sponsorship        Endocrine
                                      Education
                                      Foundation
 
LOR               2018 Annual        PCMA                     $95,000.00
                   Meeting
                   Sponsorship
 
LOR               PCMA Business      PCMA                     $80,000.00
                   Forum
                   Sponsorship
 
LOR               Cardiovascular     Association of           $30,000.00
                   Risk Reduction     Black
                   Project            Cardiologists
 
LOR               Corporate          California Life           $8,500.00
                   Sponsorship for    Sciences
                   Institute for      Association
                   Life Sciences
                   Academy
 
LOR               Friends            Friends of Cancer        $50,000.00
                   ImmunoOncology     Research
                   Programs
 
LOR               Patient Education  Prostate Cancer          $20,000.00
                   Brochure:          Education
                   Chemotherary in    Council
                   Prosate Cancer
 
LOR               2018 Patient       BIONJ Inc.                $1,000.00
                   Advocacy Summit
                   Sponsorship
 
LOR               Patient Guide      Arizona Myeloma          $10,000.00
                   Living with        Network (AZMN)
                   Myeloma
 
LOR               Yellow Fever       Fondation Merieux        $10,000.00
                   Symposium          USA, Inc.
 
LOR               Patient Education  Blood and Marrow         $40,000.00
                   Brochure on        Transplant
                   Transplantation    Information
 
LOR               MBGH Sponsorship   Midwest Business         $20,000.00
                   Request            Group on Health
 
LOR               Patient Education  American Academy         $30,000.00
                   Brochure on SCC    of Dermatology
                                      Inc.
 
LOR               HBA Woman of the   Healthcare               $22,250.00
                   Year Luncheon      Businesswomen's
                                      Association
 
LOR               Corporate          Midwest Business         $30,000.00
                   Sponsorship        Group on Health
 


------------------------------------------------------------------------
  Date of                   Primary       Primary     Physician/Teaching
  Payment       Amount      Purpose       Nature     Hospital Name (NPI)
------------------------------------------------------------------------
11/10/2015    $75,000.00  Fellowship   Cash or Cash  Vanderbilt
                                        Equivalent    University
                                                      Hospital
------------------------------------------------------------------------
06/15/2015    $74,987.00  Fellowship   Cash or Cash  Childrens Hospital
                                        Equivalent    Medical Center
------------------------------------------------------------------------
02/24/2015    $75,000.00  Fellowship   Cash or Cash  Langley Porter
                                        Equivalent    Psychiatric
                                                      Hospital
------------------------------------------------------------------------
08/01/2015    $75,000.00  Fellowship   Cash or Cash  Emory University
                                        Equivalent    Hospital
------------------------------------------------------------------------
07/01/2015    $75,000.00  Fellowship   Cash or Cash  Uci Medical Center
                                        Equivalent    (.)
------------------------------------------------------------------------
05/26/2015    $75,000.00  Fellowship   Cash or Cash  Uci Medical Center
                                        Equivalent    (.)
------------------------------------------------------------------------
04/07/2015    $43,494.57  Fellowship   Cash or Cash  University of
                                        Equivalent    Alabama Hospital
------------------------------------------------------------------------
05/17/2016    $75,000.00  Fellowship   Cash or Cash  Vanderbilt
                                        Equivalent    University
                                                      Hospitals & Cl (.)
------------------------------------------------------------------------
06/21/2016    $75,000.00  Fellowship   Cash or Cash  Emory University
                                        Equivalent    Hospital (.)
------------------------------------------------------------------------
03/09/2016    $77,537.90  Fellowship   Cash or Cash  Emory University
                                        Equivalent    Hospital (.)
------------------------------------------------------------------------
06/07/2016    $77,317.00  Fellowship   Cash or Cash  Ann & Robert H.
                                        Equivalent    Lurie Childrens
                                                      Hos (.)
------------------------------------------------------------------------
03/01/2016    $63,000.00  Fellowship   Cash or Cash  Resnick
                                        Equivalent    Neuropsychiatric
                                                      Hospital At (.)
------------------------------------------------------------------------
06/07/2016    $75,000.00  Fellowship   Cash or Cash  University Of
                                        Equivalent    Alabama Hospital
                                                      (.)
------------------------------------------------------------------------
06/27/2017    $75,000.00  Fellowship   Cash or Cash  Ann & Robert H.
                                        Equivalent    Lurie Childrens
                                                      Hos (1497018154)
------------------------------------------------------------------------
03/02/2017    $75,000.00  Fellowship   Cash or Cash  Hospital Of The
                                        Equivalent    Univ Of Penna
                                                      (1003946153)
------------------------------------------------------------------------
07/01/2017    $75,000.00  Fellowship   Cash or Cash  Cooper University
                                        Equivalent    Hospital
                                                      (1053654749)
------------------------------------------------------------------------
07/01/2017    $75,000.00  Fellowship   Cash or Cash  Childrens Hospital
                                        Equivalent    Medical Center
                                                      (1083665137)
------------------------------------------------------------------------
07/01/2017    $75,000.00  Fellowship   Cash or Cash  Uci Medical Center
                                        Equivalent    (.)
------------------------------------------------------------------------
07/01/2017    $63,000.00  Fellowship   Cash or Cash  Resnick
                                        Equivalent    Neuropsychiatric
                                                      Hospital At
                                                      (1124327853)
------------------------------------------------------------------------
12/12/2017    $75,000.00  Fellowship   Cash or Cash  Emory University
                                        Equivalent    Hospital (.)
------------------------------------------------------------------------
12/12/2017    $63,000.00  Fellowship   Cash or Cash  Resnick
                                        Equivalent    Neuropsychiatric
                                                      Hospital At
                                                      (1124327853)
------------------------------------------------------------------------
12/17/2017    $75,000.00  Fellowship   Cash or Cash  Uci Medical Center
                                        Equivalent    (.)
------------------------------------------------------------------------
12/06/2017    $75,000.00  Fellowship   Cash or Cash  Vanderbilt
                                        Equivalent    University Medical
                                                      Center
                                                      (1104202761)
------------------------------------------------------------------------
03/02/2017    $75,000.00  Fellowship   Cash or Cash  Emory University
                                        Equivalent    Hospital (.)
------------------------------------------------------------------------
03/14/2017    $73,714.12  Fellowship   Cash or Cash  University Of
                                        Equivalent    Alabama Hospital
                                                      (.)
------------------------------------------------------------------------


------------------------------------------------------------------------
  Payment Report
  Recipient Type    Address Line 1       City          State       ZIP
------------------------------------------------------------------------
Teaching hospital  1211 MEDICAL      NASHVILLE     TN              37232
                    CENTER DRIVE
------------------------------------------------------------------------
Teaching hospital  3333 BURNET       CINCINNATI    OH              45229
                    AVENUE MLC
                    #4900
------------------------------------------------------------------------
Teaching hospital  405 PARNASUS      SAN           CA              94143
                                      FRANCISCO
------------------------------------------------------------------------
Teaching hospital  1364 CLIFTON      ATLANTA       GA              30302
                    ROAD
------------------------------------------------------------------------
Teaching hospital  101 CITY DRIVE    ORANGE        CA              92868
                    SOUTH
------------------------------------------------------------------------
Teaching hospital  101 CITY DRIVE    ORANGE        CA              92868
                    SOUTH
------------------------------------------------------------------------
Teaching hospital  619 SOUTH 19TH    BIRMINGHAM    AL              35233
                    STREET
------------------------------------------------------------------------
Teaching hospital  1211 MEDICAL      NASHVILLE     TN              37232
                    CENTER DRIVE
------------------------------------------------------------------------
Teaching hospital  1364 CLIFTON      ATLANTA       GA              30302
                    ROAD
------------------------------------------------------------------------
Teaching hospital  1364 CLIFTON      ATLANTA       GA              30302
                    ROAD
------------------------------------------------------------------------
Teaching hospital  225 EAST CHICAGO  CHICAGO       IL              60611
                    AVENUE
------------------------------------------------------------------------
Teaching hospital  150 UCLA MEDICAL  LOS ANGELES   CA              90095
                    PLAZA
------------------------------------------------------------------------
Teaching hospital  619 SOUTH 19TH    BIRMINGHAM    AL              35233
                    STREET
------------------------------------------------------------------------
Teaching hospital  225 EAST CHICAGO  CHICAGO       IL              60611
                    AVENUE
------------------------------------------------------------------------
Teaching hospital  3400 SPRUCE       PHILADELPHIA  PA              19104
                    STREET
------------------------------------------------------------------------
Teaching hospital  ONE COOPER PLAZA  CAMDEN        NJ              08103
------------------------------------------------------------------------
Teaching hospital  3333 BURNET       CINCINNATI    OH              45229
                    AVENUE MLC
                    #4900
------------------------------------------------------------------------
Teaching hospital  101 CITY DRIVE    ORANGE        CA              92868
                    SOUTH
------------------------------------------------------------------------
Teaching hospital  150 UCLA MEDICAL  LOS ANGELES   CA              90095
                    PLAZA
------------------------------------------------------------------------
Teaching hospital  1364 CLIFTON      ATLANTA       GA              30302
                    ROAD
------------------------------------------------------------------------
Teaching hospital  150 UCLA MEDICAL  LOS ANGELES   CA              90095
                    PLAZA
------------------------------------------------------------------------
Teaching hospital  101 CITY DRIVE    ORANGE        CA              92868
                    SOUTH
------------------------------------------------------------------------
Teaching hospital  1211 MEDICAL      NASHVILLE     TN              37232
                    CENTER DRIVE
------------------------------------------------------------------------
Teaching hospital  1364 CLIFTON      ATLANTA       GA              30302
                    ROAD
------------------------------------------------------------------------
Teaching hospital  619 SOUTH 19TH    BIRMINGHAM    AL              35233
                    STREET
------------------------------------------------------------------------


------------------------------------------------------------------------
   Date of
   Payment         Amount         Primary Purpose       Primary Nature
------------------------------------------------------------------------
08/11/2015        $124,572.50  Investigator          Cash or Cash
                                Sponsored Trial       Equivalent
------------------------------------------------------------------------
12/15/2015         $74,327.00  Investigator          Cash or Cash
                                Sponsored Trial       Equivalent
------------------------------------------------------------------------
10/20/2015        $174,088.90  Investigator          Cash or Cash
                                Sponsored Trial       Equivalent
------------------------------------------------------------------------
09/08/2015          $5,648.00  Investigator          Cash or Cash
                                Sponsored Trial       Equivalent
------------------------------------------------------------------------
09/08/2015          $7,060.00  Investigator          Cash or Cash
                                Sponsored Trial       Equivalent
------------------------------------------------------------------------
09/08/2015          $7,060.00  Investigator          Cash or Cash
                                Sponsored Trial       Equivalent
------------------------------------------------------------------------
09/08/2015          $5,648.00  Investigator          Cash or Cash
                                Sponsored Trial       Equivalent
------------------------------------------------------------------------
09/08/2015          $4,236.00  Investigator          Cash or Cash
                                Sponsored Trial       Equivalent
------------------------------------------------------------------------
09/08/2015            $350.00  Investigator          Cash or Cash
                                Sponsored Trial       Equivalent
------------------------------------------------------------------------
09/08/2015          $1,250.00  Investigator          Cash or Cash
                                Sponsored Trial       Equivalent
------------------------------------------------------------------------
09/08/2015          $1,086.00  Investigator          Cash or Cash
                                Sponsored Trial       Equivalent
------------------------------------------------------------------------
03/24/2015          $5,648.00  Investigator          Cash or Cash
                                Sponsored Trial       Equivalent
------------------------------------------------------------------------
03/24/2015          $2,824.00  Investigator          Cash or Cash
                                Sponsored Trial       Equivalent
------------------------------------------------------------------------
03/24/2015          $2,824.00  Investigator          Cash or Cash
                                Sponsored Trial       Equivalent
------------------------------------------------------------------------
03/24/2015          $9,775.00  Investigator          Cash or Cash
                                Sponsored Trial       Equivalent
------------------------------------------------------------------------
03/24/2015            $750.00  Investigator          Cash or Cash
                                Sponsored Trial       Equivalent
------------------------------------------------------------------------
10/27/2015          $7,234.45  Investigator          Cash or Cash
                                Sponsored Trial       Equivalent
------------------------------------------------------------------------
12/08/2015         $11,074.80  Investigator          Cash or Cash
                                Sponsored Trial       Equivalent
------------------------------------------------------------------------
09/08/2015          $6,698.00  Investigator          Cash or Cash
                                Sponsored Trial       Equivalent
------------------------------------------------------------------------
09/08/2015          $1,551.00  Investigator          Cash or Cash
                                Sponsored Trial       Equivalent
------------------------------------------------------------------------
01/06/2015        $127,160.70  Investigator          Cash or Cash
                                Sponsored Trial       Equivalent
------------------------------------------------------------------------
01/06/2015        $385,403.00  Investigator          Cash or Cash
                                Sponsored Trial       Equivalent
------------------------------------------------------------------------
10/27/2015        $137,506.80  Investigator          Cash or Cash
                                Sponsored Trial       Equivalent
------------------------------------------------------------------------
02/24/2015         $35,672.06  Investigator          Cash or Cash
                                Sponsored Trial       Equivalent
------------------------------------------------------------------------
03/17/2015         $36,130.95  Investigator          Cash or Cash
                                Sponsored Trial       Equivalent
------------------------------------------------------------------------
09/15/2015          $7,226.19  Investigator          Cash or Cash
                                Sponsored Trial       Equivalent
------------------------------------------------------------------------
02/10/2015        $325,000.00  Investigator          Cash or Cash
                                Sponsored Trial       Equivalent
------------------------------------------------------------------------
10/20/2015          $5,000.00  Investigator          Cash or Cash
                                Sponsored Trial       Equivalent
------------------------------------------------------------------------
07/21/2015          $5,000.00  Investigator          Cash or Cash
                                Sponsored Trial       Equivalent
------------------------------------------------------------------------
07/07/2015         $49,000.00  Investigator          Cash or Cash
                                Sponsored Trial       Equivalent
------------------------------------------------------------------------
07/21/2015         $16,089.68  Investigator          Cash or Cash
                                Sponsored Trial       Equivalent
------------------------------------------------------------------------
06/02/2015         $14,000.00  Investigator          Cash or Cash
                                Sponsored Trial       Equivalent
------------------------------------------------------------------------
02/10/2015          $5,000.00  Investigator          Cash or Cash
                                Sponsored Trial       Equivalent
------------------------------------------------------------------------
01/06/2015         $20,100.00  Investigator          Cash or Cash
                                Sponsored Trial       Equivalent
------------------------------------------------------------------------
03/24/2015          $1,412.00  Investigator          Cash or Cash
                                Sponsored Trial       Equivalent
------------------------------------------------------------------------
03/24/2015          $1,412.00  Investigator          Cash or Cash
                                Sponsored Trial       Equivalent
------------------------------------------------------------------------
03/24/2015          $1,412.00  Investigator          Cash or Cash
                                Sponsored Trial       Equivalent
------------------------------------------------------------------------
04/14/2015          $8,363.00  Investigator          Cash or Cash
                                Sponsored Trial       Equivalent
------------------------------------------------------------------------
09/08/2015          $7,760.00  Investigator          Cash or Cash
                                Sponsored Trial       Equivalent
------------------------------------------------------------------------
03/03/2015          $4,000.00  Investigator          Cash or Cash
                                Sponsored Trial       Equivalent
------------------------------------------------------------------------
10/27/2015         $28,585.85  Investigator          Cash or Cash
                                Sponsored Trial       Equivalent
------------------------------------------------------------------------
04/14/2015         $85,757.55  Investigator          Cash or Cash
                                Sponsored Trial       Equivalent
------------------------------------------------------------------------
10/20/2015         $28,585.85  Investigator          Cash or Cash
                                Sponsored Trial       Equivalent
------------------------------------------------------------------------
03/03/2015         $61,725.52  Investigator          Cash or Cash
                                Sponsored Trial       Equivalent
------------------------------------------------------------------------
03/03/2015         $11,176.62  Investigator          Cash or Cash
                                Sponsored Trial       Equivalent
------------------------------------------------------------------------
03/03/2015         $24,246.00  Investigator          Cash or Cash
                                Sponsored Trial       Equivalent
------------------------------------------------------------------------
10/13/2015        $125,000.00  Investigator          Cash or Cash
                                Sponsored Trial       Equivalent
------------------------------------------------------------------------
12/15/2015        $200,000.00  Investigator          Fees
                                Sponsored Trial
------------------------------------------------------------------------
01/13/2015         $39,771.64  Investigator          Cash or Cash
                                Sponsored Trial       Equivalent
------------------------------------------------------------------------
05/05/2015         $39,771.64  Investigator          Cash or Cash
                                Sponsored Trial       Equivalent
------------------------------------------------------------------------
06/09/2015         $39,771.65  Investigator          Cash or Cash
                                Sponsored Trial       Equivalent
------------------------------------------------------------------------
05/19/2015        $119,166.66  Investigator          Cash or Cash
                                Sponsored Trial       Equivalent
------------------------------------------------------------------------
05/26/2015        $185,900.01  Investigator          Cash or Cash
                                Sponsored Trial       Equivalent
------------------------------------------------------------------------
06/02/2015         $61,966.67  Investigator          Cash or Cash
                                Sponsored Trial       Equivalent
------------------------------------------------------------------------
07/28/2015         $61,966.66  Investigator          Cash or Cash
                                Sponsored Trial       Equivalent
------------------------------------------------------------------------
03/17/2015        $126,059.09  Investigator          Cash or Cash
                                Sponsored Trial       Equivalent
------------------------------------------------------------------------
03/17/2015        $126,059.09  Investigator          Cash or Cash
                                Sponsored Trial       Equivalent
------------------------------------------------------------------------
04/07/2015        $174,088.90  Investigator          Cash or Cash
                                Sponsored Trial       Equivalent
------------------------------------------------------------------------
01/06/2015         $59,187.50  Investigator          Cash or Cash
                                Sponsored Trial       Equivalent
------------------------------------------------------------------------
05/19/2015         $59,187.50  Investigator          Cash or Cash
                                Sponsored Trial       Equivalent
------------------------------------------------------------------------
04/14/2015         $11,120.67  Investigator          Cash or Cash
                                Sponsored Trial       Equivalent
------------------------------------------------------------------------
05/26/2015         $28,612.00  Investigator          Cash or Cash
                                Sponsored Trial       Equivalent
------------------------------------------------------------------------
06/16/2015         $28,612.00  Investigator          Cash or Cash
                                Sponsored Trial       Equivalent
------------------------------------------------------------------------
08/11/2015          $7,234.45  Investigator          Cash or Cash
                                Sponsored Trial       Equivalent
------------------------------------------------------------------------
03/24/2015         $28,830.75  Investigator          Cash or Cash
                                Sponsored Trial       Equivalent
------------------------------------------------------------------------
02/17/2015         $30,167.85  Investigator          Cash or Cash
                                Sponsored Trial       Equivalent
------------------------------------------------------------------------
03/17/2015         $24,228.75  Investigator          Cash or Cash
                                Sponsored Trial       Equivalent
------------------------------------------------------------------------
08/11/2015        $355,830.00  Investigator          Cash or Cash
                                Sponsored Trial       Equivalent
------------------------------------------------------------------------
05/26/2015         $28,777.00  Investigator          Cash or Cash
                                Sponsored Trial       Equivalent
------------------------------------------------------------------------
03/17/2015          $8,329.00  Investigator          Cash or Cash
                                Sponsored Trial       Equivalent
------------------------------------------------------------------------
04/14/2015          $9,229.00  Investigator          Cash or Cash
                                Sponsored Trial       Equivalent
------------------------------------------------------------------------
11/19/2015         $53,400.00  Investigator          Product
                                Sponsored Trial
------------------------------------------------------------------------
12/10/2015        $214,706.70  Investigator          Product
                                Sponsored Trial
------------------------------------------------------------------------
12/17/2015          $7,425.18  Investigator          Product
                                Sponsored Trial
------------------------------------------------------------------------
11/23/2015         $12,375.30  Investigator          Product
                                Sponsored Trial
------------------------------------------------------------------------
12/07/2015        $160,228.80  Investigator          Product
                                Sponsored Trial
------------------------------------------------------------------------
11/23/2015         $14,850.36  Investigator          Product
                                Sponsored Trial
------------------------------------------------------------------------
01/26/2016        $114,107.36  Investigator          Cash or Cash
                                Sponsored Trial       Equivalent
------------------------------------------------------------------------
01/12/2016        $250,000.00  Investigator          Cash or Cash
                                Sponsored Trial       Equivalent
------------------------------------------------------------------------
04/26/2016         $54,115.17  Investigator          Cash or Cash
                                Sponsored Trial       Equivalent
------------------------------------------------------------------------
05/17/2016        $174,088.90  Investigator          Cash or Cash
                                Sponsored Trial       Equivalent
------------------------------------------------------------------------
01/26/2016         $35,000.00  Investigator          Cash or Cash
                                Sponsored Trial       Equivalent
------------------------------------------------------------------------
06/02/2016         $18,334.48  Investigator          Cash or Cash
                                Sponsored Trial       Equivalent
------------------------------------------------------------------------
09/13/2016        $174,088.90  Investigator          Cash or Cash
                                Sponsored Trial       Equivalent
------------------------------------------------------------------------
06/28/2016        $224,593.02  Investigator          Cash or Cash
                                Sponsored Trial       Equivalent
------------------------------------------------------------------------
09/13/2016         $22,950.00  Investigator          Cash or Cash
                                Sponsored Trial       Equivalent
------------------------------------------------------------------------
02/09/2016         $50,279.75  Investigator          Cash or Cash
                                Sponsored Trial       Equivalent
------------------------------------------------------------------------
04/19/2016         $28,830.75  Investigator          Cash or Cash
                                Sponsored Trial       Equivalent
------------------------------------------------------------------------
01/12/2016         $24,228.75  Investigator          Cash or Cash
                                Sponsored Trial       Equivalent
------------------------------------------------------------------------
01/19/2016         $24,228.75  Investigator          Cash or Cash
                                Sponsored Trial       Equivalent
------------------------------------------------------------------------
04/26/2016         $33,332.00  Investigator          Cash or Cash
                                Sponsored Trial       Equivalent
------------------------------------------------------------------------
03/08/2016         $30,589.00  Investigator          Cash or Cash
                                Sponsored Trial       Equivalent
------------------------------------------------------------------------
07/19/2016          $7,234.45  Investigator          Cash or Cash
                                Sponsored Trial       Equivalent
------------------------------------------------------------------------
06/28/2016         $15,750.00  Investigator          Cash or Cash
                                Sponsored Trial       Equivalent
------------------------------------------------------------------------
09/27/2016         $42,502.00  Investigator          Cash or Cash
                                Sponsored Trial       Equivalent
------------------------------------------------------------------------
06/07/2016         $38,530.00  Investigator          Product
                                Sponsored Trial
------------------------------------------------------------------------
06/15/2016         $22,106.80  Investigator          Product
                                Sponsored Trial
------------------------------------------------------------------------
06/16/2016          $3,103.89  Investigator          Product
                                Sponsored Trial
------------------------------------------------------------------------
06/22/2016        $114,600.84  Investigator          Product
                                Sponsored Trial
------------------------------------------------------------------------
06/23/2016         $88,057.50  Investigator          Product
                                Sponsored Trial
------------------------------------------------------------------------
06/27/2016         $12,930.00  Investigator          Product
                                Sponsored Trial
------------------------------------------------------------------------
01/13/2016         $18,768.00  Investigator          Product
                                Sponsored Trial
------------------------------------------------------------------------
01/14/2016         $88,057.50  Investigator          Product
                                Sponsored Trial
------------------------------------------------------------------------
01/14/2016         $58,710.00  Investigator          Product
                                Sponsored Trial
------------------------------------------------------------------------
01/14/2016            $959.62  Investigator          Product
                                Sponsored Trial
------------------------------------------------------------------------
01/14/2016          $3,047.08  Investigator          Product
                                Sponsored Trial
------------------------------------------------------------------------
01/14/2016          $1,556.04  Investigator          Product
                                Sponsored Trial
------------------------------------------------------------------------
01/14/2016          $3,941.70  Investigator          Product
                                Sponsored Trial
------------------------------------------------------------------------
01/14/2016            $661.42  Investigator          Product
                                Sponsored Trial
------------------------------------------------------------------------
01/27/2016        $293,490.00  Investigator          Product
                                Sponsored Trial
------------------------------------------------------------------------
02/09/2016         $12,505.30  Investigator          Product
                                Sponsored Trial
------------------------------------------------------------------------
02/12/2016         $76,515.00  Investigator          Product
                                Sponsored Trial
------------------------------------------------------------------------
02/16/2016         $36,067.85  Investigator          Product
                                Sponsored Trial
------------------------------------------------------------------------
02/18/2016         $58,710.00  Investigator          Product
                                Sponsored Trial
------------------------------------------------------------------------
03/29/2016         $12,930.00  Investigator          Product
                                Sponsored Trial
------------------------------------------------------------------------
03/29/2016         $64,130.00  Investigator          Product
                                Sponsored Trial
------------------------------------------------------------------------
03/29/2016         $25,730.00  Investigator          Product
                                Sponsored Trial
------------------------------------------------------------------------
03/31/2016          $3,103.89  Investigator          Product
                                Sponsored Trial
------------------------------------------------------------------------
04/04/2016         $76,930.00  Investigator          Product
                                Sponsored Trial
------------------------------------------------------------------------
04/13/2016         $58,710.00  Investigator          Product
                                Sponsored Trial
------------------------------------------------------------------------
04/19/2016        $152,796.13  Investigator          Product
                                Sponsored Trial
------------------------------------------------------------------------
04/28/2016         $12,930.00  Investigator          Product
                                Sponsored Trial
------------------------------------------------------------------------
05/05/2016         $12,505.30  Investigator          Product
                                Sponsored Trial
------------------------------------------------------------------------
05/09/2016        $153,730.00  Investigator          Product
                                Sponsored Trial
------------------------------------------------------------------------
05/09/2016         $51,015.00  Investigator          Product
                                Sponsored Trial
------------------------------------------------------------------------
05/24/2016        $576,860.60  Investigator          Product
                                Sponsored Trial
------------------------------------------------------------------------
05/25/2016        $117,405.00  Investigator          Product
                                Sponsored Trial
------------------------------------------------------------------------
07/06/2016        $117,405.00  Investigator          Product
                                Sponsored Trial
------------------------------------------------------------------------
07/13/2016        $352,185.00  Investigator          Product
                                Sponsored Trial
------------------------------------------------------------------------
07/13/2016         $58,710.00  Investigator          Product
                                Sponsored Trial
------------------------------------------------------------------------
07/25/2016         $11,312.95  Investigator          Product
                                Sponsored Trial
------------------------------------------------------------------------
07/26/2016         $15,040.60  Investigator          Product
                                Sponsored Trial
------------------------------------------------------------------------
07/26/2016         $21,998.88  Investigator          Product
                                Sponsored Trial
------------------------------------------------------------------------
07/26/2016         $27,466.10  Investigator          Product
                                Sponsored Trial
------------------------------------------------------------------------
07/26/2016         $24,981.00  Investigator          Product
                                Sponsored Trial
------------------------------------------------------------------------
07/27/2016          $7,585.30  Investigator          Product
                                Sponsored Trial
------------------------------------------------------------------------
07/27/2016         $27,963.12  Investigator          Product
                                Sponsored Trial
------------------------------------------------------------------------
07/28/2016         $12,505.30  Investigator          Product
                                Sponsored Trial
------------------------------------------------------------------------
08/31/2016         $12,930.00  Investigator          Product
                                Sponsored Trial
------------------------------------------------------------------------
09/01/2016         $22,106.80  Investigator          Product
                                Sponsored Trial
------------------------------------------------------------------------
09/14/2016          $3,103.89  Investigator          Product
                                Sponsored Trial
------------------------------------------------------------------------
09/27/2016         $88,057.50  Investigator          Product
                                Sponsored Trial
------------------------------------------------------------------------
10/10/2016         $72,120.70  Investigator          Product
                                Sponsored Trial
------------------------------------------------------------------------
10/19/2016         $22,106.80  Investigator          Product
                                Sponsored Trial
------------------------------------------------------------------------
10/24/2016         $12,505.30  Investigator          Product
                                Sponsored Trial
------------------------------------------------------------------------
10/31/2016        $293,760.00  Investigator          Product
                                Sponsored Trial
------------------------------------------------------------------------
10/31/2016         $58,764.00  Investigator          Product
                                Sponsored Trial
------------------------------------------------------------------------
10/31/2016         $12,930.00  Investigator          Product
                                Sponsored Trial
------------------------------------------------------------------------
10/31/2016         $58,764.00  Investigator          Product
                                Sponsored Trial
------------------------------------------------------------------------
11/01/2016         $29,389.50  Investigator          Product
                                Sponsored Trial
------------------------------------------------------------------------
11/15/2016         $77,933.40  Investigator          Product
                                Sponsored Trial
------------------------------------------------------------------------
11/17/2016         $58,764.00  Investigator          Product
                                Sponsored Trial
------------------------------------------------------------------------
11/21/2016         $19,265.00  Investigator          Product
                                Sponsored Trial
------------------------------------------------------------------------
11/21/2016        $134,465.00  Investigator          Product
                                Sponsored Trial
------------------------------------------------------------------------
12/14/2016         $88,138.50  Investigator          Product
                                Sponsored Trial
------------------------------------------------------------------------
12/19/2016        $293,760.00  Investigator          Product
                                Sponsored Trial
------------------------------------------------------------------------
04/05/2016            $382.26  Investigator          Product
                                Sponsored Trial
------------------------------------------------------------------------
10/17/2016            $449.71  Investigator          Product
                                Sponsored Trial
------------------------------------------------------------------------
05/09/2016      $1,122,210.00  Investigator          Fees
                                Sponsored Trial
------------------------------------------------------------------------
12/08/2016      $1,122,209.00  Investigator          Fees
                                Sponsored Trial
------------------------------------------------------------------------
02/16/2016         $59,187.50  Investigator          Cash or Cash
                                Sponsored Trial       Equivalent
------------------------------------------------------------------------
10/18/2016         $67,970.00  Investigator          Cash or Cash
                                Sponsored Trial       Equivalent
------------------------------------------------------------------------
01/26/2016         $19,474.93  Investigator          Cash or Cash
                                Sponsored Trial       Equivalent
------------------------------------------------------------------------
06/02/2016         $47,400.50  Investigator          Cash or Cash
                                Sponsored Trial       Equivalent
------------------------------------------------------------------------
12/13/2016         $47,400.50  Investigator          Cash or Cash
                                Sponsored Trial       Equivalent
------------------------------------------------------------------------
01/04/2017            $862.56  Investigator          Product
                                Sponsored Trial
------------------------------------------------------------------------
01/10/2017         $12,930.00  Investigator          Product
                                Sponsored Trial
------------------------------------------------------------------------
01/11/2017          $6,317.65  Investigator          Product
                                Sponsored Trial
------------------------------------------------------------------------
01/16/2017            $862.56  Investigator          Product
                                Sponsored Trial
------------------------------------------------------------------------
01/18/2017         $29,362.50  Investigator          Product
                                Sponsored Trial
------------------------------------------------------------------------
01/24/2017         $11,247.95  Investigator          Product
                                Sponsored Trial
------------------------------------------------------------------------
01/24/2017            $288.66  Investigator          Product
                                Sponsored Trial
------------------------------------------------------------------------
01/24/2017         $11,247.95  Investigator          Product
                                Sponsored Trial
------------------------------------------------------------------------
01/24/2017          $1,108.73  Investigator          Product
                                Sponsored Trial
------------------------------------------------------------------------
01/24/2017         $19,945.80  Investigator          Product
                                Sponsored Trial
------------------------------------------------------------------------
01/24/2017          $4,538.12  Investigator          Product
                                Sponsored Trial
------------------------------------------------------------------------
01/24/2017         $13,549.36  Investigator          Product
                                Sponsored Trial
------------------------------------------------------------------------
01/24/2017          $3,112.08  Investigator          Product
                                Sponsored Trial
------------------------------------------------------------------------
01/24/2017         $24,916.00  Investigator          Product
                                Sponsored Trial
------------------------------------------------------------------------
01/24/2017            $810.52  Investigator          Product
                                Sponsored Trial
------------------------------------------------------------------------
02/08/2017            $884.54  Investigator          Product
                                Sponsored Trial
------------------------------------------------------------------------
03/01/2017            $884.54  Investigator          Product
                                Sponsored Trial
------------------------------------------------------------------------
03/13/2017         $25,730.00  Investigator          Product
                                Sponsored Trial
------------------------------------------------------------------------
03/16/2017         $58,710.00  Investigator          Product
                                Sponsored Trial
------------------------------------------------------------------------
03/29/2017          $6,317.65  Investigator          Product
                                Sponsored Trial
------------------------------------------------------------------------
03/30/2017        $145,308.00  Investigator          Product
                                Sponsored Trial
------------------------------------------------------------------------
04/06/2017         $58,710.00  Investigator          Product
                                Sponsored Trial
------------------------------------------------------------------------
05/01/2017         $58,710.00  Investigator          Product
                                Sponsored Trial
------------------------------------------------------------------------
05/08/2017         $45,402.40  Investigator          Product
                                Sponsored Trial
------------------------------------------------------------------------
05/18/2017         $29,362.50  Investigator          Product
                                Sponsored Trial
------------------------------------------------------------------------
05/25/2017         $29,362.50  Investigator          Product
                                Sponsored Trial
------------------------------------------------------------------------
06/08/2017         $22,766.20  Investigator          Product
                                Sponsored Trial
------------------------------------------------------------------------
06/12/2017         $22,766.20  Investigator          Product
                                Sponsored Trial
------------------------------------------------------------------------
06/15/2017         $29,362.50  Investigator          Product
                                Sponsored Trial
------------------------------------------------------------------------
06/15/2017         $29,362.50  Investigator          Product
                                Sponsored Trial
------------------------------------------------------------------------
06/29/2017         $14,980.36  Investigator          Product
                                Sponsored Trial
------------------------------------------------------------------------
07/05/2017         $58,710.00  Investigator          Product
                                Sponsored Trial
------------------------------------------------------------------------
07/13/2017         $58,710.00  Investigator          Product
                                Sponsored Trial
------------------------------------------------------------------------
07/17/2017         $58,710.00  Investigator          Product
                                Sponsored Trial
------------------------------------------------------------------------
07/25/2017         $58,710.00  Investigator          Product
                                Sponsored Trial
------------------------------------------------------------------------
07/25/2017         $19,945.80  Investigator          Product
                                Sponsored Trial
------------------------------------------------------------------------
07/25/2017         $10,129.40  Investigator          Product
                                Sponsored Trial
------------------------------------------------------------------------
07/25/2017         $10,194.40  Investigator          Product
                                Sponsored Trial
------------------------------------------------------------------------
07/25/2017         $24,916.00  Investigator          Product
                                Sponsored Trial
------------------------------------------------------------------------
07/25/2017          $2,413.36  Investigator          Product
                                Sponsored Trial
------------------------------------------------------------------------
08/02/2017         $58,710.00  Investigator          Product
                                Sponsored Trial
------------------------------------------------------------------------
08/15/2017         $15,220.80  Investigator          Product
                                Sponsored Trial
------------------------------------------------------------------------
08/24/2017        $440,227.50  Investigator          Product
                                Sponsored Trial
------------------------------------------------------------------------
09/20/2017         $30,311.60  Investigator          Product
                                Sponsored Trial
------------------------------------------------------------------------
09/21/2017         $14,980.36  Investigator          Product
                                Sponsored Trial
------------------------------------------------------------------------
10/18/2017         $58,710.00  Investigator          Product
                                Sponsored Trial
------------------------------------------------------------------------
10/30/2017        $305,489.41  Investigator          Product
                                Sponsored Trial
------------------------------------------------------------------------
11/29/2017          $6,855.86  Investigator          Product
                                Sponsored Trial
------------------------------------------------------------------------
11/29/2017         $40,810.16  Investigator          Product
                                Sponsored Trial
------------------------------------------------------------------------
12/18/2017        $162,934.69  Investigator          Product
                                Sponsored Trial
------------------------------------------------------------------------
12/20/2017      $1,163,061.00  Investigator          Fees
                                Sponsored Trial
------------------------------------------------------------------------
12/20/2017        $831,459.00  Investigator          Fees
                                Sponsored Trial
------------------------------------------------------------------------
04/12/2017        $140,654.12  Investigator          Fees
                                Sponsored Trial
------------------------------------------------------------------------
10/01/2017         $75,158.78  Investigator          Fees
                                Sponsored Trial
------------------------------------------------------------------------
10/25/2017         $53,668.90  Investigator          Fees
                                Sponsored Trial
------------------------------------------------------------------------
10/20/2017        $391,759.00  Investigator          Fees
                                Sponsored Trial
------------------------------------------------------------------------
11/21/2017         $76,900.00  Investigator          Fees
                                Sponsored Trial
------------------------------------------------------------------------
09/12/2017         $55,768.59  Investigator          Fees
                                Sponsored Trial
------------------------------------------------------------------------
07/18/2017         $77,522.30  Investigator          Cash or Cash
                                Sponsored Trial       Equivalent
------------------------------------------------------------------------
03/02/2017          $7,955.33  Investigator          Cash or Cash
                                Sponsored Trial       Equivalent
------------------------------------------------------------------------
07/06/2017         $43,280.58  Investigator          Cash or Cash
                                Sponsored Trial       Equivalent
------------------------------------------------------------------------
01/17/2017        $244,633.00  Investigator          Cash or Cash
                                Sponsored Trial       Equivalent
------------------------------------------------------------------------
01/17/2017         $37,134.00  Investigator          Cash or Cash
                                Sponsored Trial       Equivalent
------------------------------------------------------------------------
02/21/2017          $6,000.00  Investigator          Cash or Cash
                                Sponsored Trial       Equivalent
------------------------------------------------------------------------
04/04/2017          $7,234.45  Investigator          Cash or Cash
                                Sponsored Trial       Equivalent
------------------------------------------------------------------------
05/23/2017         $50,279.75  Investigator          Cash or Cash
                                Sponsored Trial       Equivalent
------------------------------------------------------------------------
08/15/2017         $92,654.93  Investigator          ...................
                                Sponsored Trial
                                Cash or Cash
                                Equivalent
------------------------------------------------------------------------
04/25/2017        $128,325.90  Investigator          Cash or Cash
                                Sponsored Trial       Equivalent
------------------------------------------------------------------------
07/18/2017        $128,325.90  Investigator          Cash or Cash
                                Sponsored Trial       Equivalent
------------------------------------------------------------------------
09/05/2017        $128,325.90  Investigator          Cash or Cash
                                Sponsored Trial       Equivalent
------------------------------------------------------------------------
11/07/2017        $128,325.90  Investigator          Cash or Cash
                                Sponsored Trial       Equivalent
------------------------------------------------------------------------
05/09/2017         $66,562.62  Investigator          Cash or Cash
                                Sponsored Trial       Equivalent
------------------------------------------------------------------------
07/06/2017         $66,562.62  Investigator          Cash or Cash
                                Sponsored Trial       Equivalent
------------------------------------------------------------------------
10/03/2017         $66,562.62  Investigator          Cash or Cash
                                Sponsored Trial       Equivalent
------------------------------------------------------------------------
05/02/2017         $80,715.00  Investigator          Cash or Cash
                                Sponsored Trial       Equivalent
------------------------------------------------------------------------
01/04/2017         $47,400.50  Investigator          Cash or Cash
                                Sponsored Trial       Equivalent
------------------------------------------------------------------------
01/04/2017         $47,400.97  Investigator          Cash or Cash
                                Sponsored Trial       Equivalent
------------------------------------------------------------------------
01/17/2017        $100,000.00  Investigator          Cash or Cash
                                Sponsored Trial       Equivalent
------------------------------------------------------------------------
03/02/2017         $26,701.00  Investigator          Cash or Cash
                                Sponsored Trial       Equivalent
------------------------------------------------------------------------
04/18/2017        $190,471.20  Investigator          Cash or Cash
                                Sponsored Trial       Equivalent
------------------------------------------------------------------------
08/15/2017          $2,100.00  Investigator          Cash or Cash
                                Sponsored Trial       Equivalent
------------------------------------------------------------------------
11/14/2017         $23,348.00  Investigator          Cash or Cash
                                Sponsored Trial       Equivalent
------------------------------------------------------------------------
05/30/2017        $140,654.12  Investigator          Cash or Cash
                                Sponsored Trial       Equivalent
------------------------------------------------------------------------
09/19/2017        $188,832.43  Investigator          Cash or Cash
                                Sponsored Trial       Equivalent
------------------------------------------------------------------------
12/05/2017          $2,835.71  Investigator          Cash or Cash
                                Sponsored Trial       Equivalent
------------------------------------------------------------------------
01/22/2018         $16,681.38  Investigator          Product
                                Sponsored Trial
------------------------------------------------------------------------
01/22/2018            $427.27  Investigator          Product
                                Sponsored Trial
------------------------------------------------------------------------
01/22/2018            $750.53  Investigator          Product
                                Sponsored Trial
------------------------------------------------------------------------
01/23/2018         $15,679.17  Investigator          Product
                                Sponsored Trial
------------------------------------------------------------------------
01/23/2018          $3,904.40  Investigator          Product
                                Sponsored Trial
------------------------------------------------------------------------
01/23/2018         $12,928.50  Investigator          Product
                                Sponsored Trial
------------------------------------------------------------------------
01/25/2018         $25,640.33  Investigator          Product
                                Sponsored Trial
------------------------------------------------------------------------
01/25/2018          $1,118.37  Investigator          Product
                                Sponsored Trial
------------------------------------------------------------------------
01/25/2018          $2,872.13  Investigator          Product
                                Sponsored Trial
------------------------------------------------------------------------
01/29/2018        $712,788.63  Investigator          Product
                                Sponsored Trial
------------------------------------------------------------------------
02/20/2018        $152,752.20  Investigator          Product
                                Sponsored Trial
------------------------------------------------------------------------
04/11/2018        $314,348.09  Investigator          Product
                                Sponsored Trial
------------------------------------------------------------------------
04/17/2018         $19,930.48  Investigator          Product
                                Sponsored Trial
------------------------------------------------------------------------
05/22/2018        $261,959.23  Investigator          Product
                                Sponsored Trial
------------------------------------------------------------------------
05/29/2018        $157,181.55  Investigator          Product
                                Sponsored Trial
------------------------------------------------------------------------
07/10/2018         $16,302.40  Investigator          Product
                                Sponsored Trial
------------------------------------------------------------------------
07/10/2018         $13,607.00  Investigator          Product
                                Sponsored Trial
------------------------------------------------------------------------
07/12/2018         $17,650.10  Investigator          Product
                                Sponsored Trial
------------------------------------------------------------------------
07/12/2018         $27,084.00  Investigator          Product
                                Sponsored Trial
------------------------------------------------------------------------
07/17/2018        $209,570.39  Investigator          Product
                                Sponsored Trial
------------------------------------------------------------------------
07/19/2018         $88,057.50  Investigator          Product
                                Sponsored Trial
------------------------------------------------------------------------
08/14/2018         $58,710.00  Investigator          Product
                                Sponsored Trial
------------------------------------------------------------------------
08/20/2018         $58,710.00  Investigator          Product
                                Sponsored Trial
------------------------------------------------------------------------
08/23/2018        $117,405.00  Investigator          Product
                                Sponsored Trial
------------------------------------------------------------------------
09/17/2018        $157,181.55  Investigator          Product
                                Sponsored Trial
------------------------------------------------------------------------
09/27/2018        $157,181.55  Investigator          Product
                                Sponsored Trial
------------------------------------------------------------------------
10/29/2018        $261,959.23  Investigator          Product
                                Sponsored Trial
------------------------------------------------------------------------
11/28/2018         $58,710.00  Investigator          Product
                                Sponsored Trial
------------------------------------------------------------------------
11/29/2018        $104,792.70  Investigator          Product
                                Sponsored Trial
------------------------------------------------------------------------
11/26/2018            $348.48  Investigator          Supplies
                                Sponsored Trial
------------------------------------------------------------------------
11/26/2018             $28.32  Investigator          Supplies
                                Sponsored Trial
------------------------------------------------------------------------
04/25/2018             $67.25  Investigator          Supplies
                                Sponsored Trial
------------------------------------------------------------------------
08/28/2018            $281.36  Investigator          Supplies
                                Sponsored Trial
------------------------------------------------------------------------
11/27/2018        $793,755.00  Investigator          Fees
                                Sponsored Trial
------------------------------------------------------------------------
09/24/2018        $277,130.00  Investigator          Investigator Fees
                                Sponsored Trial
------------------------------------------------------------------------
10/19/2018        $207,848.00  Investigator          Investigator Fees
                                Sponsored Trial
------------------------------------------------------------------------
03/20/2018         $26,125.00  Investigator          Cash or Cash
                                Sponsored Trial       Equivalent
------------------------------------------------------------------------
01/30/2018         $76,900.00  Investigator          Cash or Cash
                                Sponsored Trial       Equivalent
------------------------------------------------------------------------
06/12/2018         $29,796.00  Investigator          Cash or Cash
                                Sponsored Trial       Equivalent
------------------------------------------------------------------------
02/20/2018        $178,970.30  Investigator          Cash or Cash
                                Sponsored Trial       Equivalent
------------------------------------------------------------------------
01/16/2018        $244,633.00  Investigator          Cash or Cash
                                Sponsored Trial       Equivalent
------------------------------------------------------------------------
02/06/2018        $128,325.90  Investigator          Cash or Cash
                                Sponsored Trial       Equivalent
------------------------------------------------------------------------
09/06/2018        $128,325.90  Investigator          Cash or Cash
                                Sponsored Trial       Equivalent
------------------------------------------------------------------------
09/06/2018        $128,325.90  Investigator          Cash or Cash
                                Sponsored Trial       Equivalent
------------------------------------------------------------------------
04/19/2018         $66,562.62  Investigator          Cash or Cash
                                Sponsored Trial       Equivalent
------------------------------------------------------------------------
05/15/2018         $35,581.00  Investigator          Cash or Cash
                                Sponsored Trial       Equivalent
------------------------------------------------------------------------
05/15/2018         $30,030.00  Investigator          Cash or Cash
                                Sponsored Trial       Equivalent
------------------------------------------------------------------------
06/19/2018         $52,087.00  Investigator          Cash or Cash
                                Sponsored Trial       Equivalent
------------------------------------------------------------------------
07/23/2018         $31,131.00  Investigator          Cash or Cash
                                Sponsored Trial       Equivalent
------------------------------------------------------------------------
01/30/2018         $14,223.80  Investigator          Cash or Cash
                                Sponsored Trial       Equivalent
------------------------------------------------------------------------
04/03/2018        $144,601.03  Investigator          Cash or Cash
                                Sponsored Trial       Equivalent
------------------------------------------------------------------------
08/02/2018         $47,500.00  Investigator          Cash or Cash
                                Sponsored Trial       Equivalent
------------------------------------------------------------------------
08/02/2018        $148,734.45  Investigator          Cash or Cash
                                Sponsored Trial       Equivalent
------------------------------------------------------------------------
03/29/2018        $238,670.00  Investigator          Cash or Cash
                                Sponsored Trial       Equivalent
------------------------------------------------------------------------
04/05/2018        $104,418.67  Investigator          Cash or Cash
                                Sponsored Trial       Equivalent
------------------------------------------------------------------------
05/10/2018          $7,939.00  Investigator          Cash or Cash
                                Sponsored Trial       Equivalent
------------------------------------------------------------------------
11/26/2018         $14,624.00  Investigator          Cash or Cash
                                Sponsored Trial       Equivalent
------------------------------------------------------------------------
01/09/2018        $100,000.00  Investigator          Cash or Cash
                                Sponsored Trial       Equivalent
------------------------------------------------------------------------
01/02/2018         $53,668.90  Investigator          Cash or Cash
                                Sponsored Trial       Equivalent
------------------------------------------------------------------------
01/05/2018        $391,759.00  Investigator          Cash or Cash
                                Sponsored Trial       Equivalent
------------------------------------------------------------------------
05/08/2018         $28,610.89  Investigator          Cash or Cash
                                Sponsored Trial       Equivalent
------------------------------------------------------------------------
10/29/2018         $78,100.80  Investigator          Cash or Cash
                                Sponsored Trial       Equivalent
------------------------------------------------------------------------
08/21/2018         $29,796.00  Investigator          Cash or Cash
                                Sponsored Trial       Equivalent
------------------------------------------------------------------------
11/19/2018        $103,543.60  Investigator          Cash or Cash
                                Sponsored Trial       Equivalent
------------------------------------------------------------------------
11/19/2018         $97,510.18  Investigator          Cash or Cash
                                Sponsored Trial       Equivalent
------------------------------------------------------------------------
12/10/2018         $48,814.00  Investigator          Cash or Cash
                                Sponsored Trial       Equivalent
------------------------------------------------------------------------
11/19/2018         $72,000.00  Investigator          Cash or Cash
                                Sponsored Trial       Equivalent
------------------------------------------------------------------------


------------------------------------------------------------------------
  Physician/
   Teaching       Address
 Hospital Name    Line 1       City    State      ZIP     Name of Study
     (NPI)
------------------------------------------------------------------------
Montefiore      111 EAST     BRONX    NY         10467  A roadmap for
 Medical         210TH                                   the conversion
 Center          STREET                                  from sliding
                                                         scale to basal
                                                         insulin in the
                                                         long term care
                                                         setting.
------------------------------------------------------------------------
Langley Porter  405          SAN      CA         94143  A Phase I Study
 Psychiatric     PARNASUS     FRANCI                     of Cabazitaxel,
                              SCO                        Mitoxanthrone,
                                                         and Prednison
                                                         (CAMP) for
                                                         Patients with
                                                         Metastatic
                                                         Castration-
                                                         Resistant
                                                         Prostate Cancer
                                                         and no Prior
                                                         Chemotherapy
------------------------------------------------------------------------
Memorial        1275 YORK    NEW      NY         10065  An Exploratory
 Hospital for    AVENUE       YORK                       Randomized
 Cancer and                                              Phase II
 Allied                                                  Multicenter
 Diseases                                                Trial of
                                                         Abiraterone
                                                         Acetate with or
                                                         without
                                                         Cabazitaxel in
                                                         Treatment of
                                                         Metastatic
                                                         Castration
                                                         Resistant
                                                         Prostate Cancer
------------------------------------------------------------------------
University of   5841 SOUTH   CHICAGO  IL         60637  A study of the
 Chicago         MARYLAND                                effects of
 Hospital        AVENUE                                  Alemtuzumab on
                                                         Surrogate
                                                         Markers of
                                                         Disease
                                                         Activity and
                                                         Repair using
                                                         Advanced MRI
                                                         measures in
                                                         Subjects with
                                                         Relapsing
                                                         Remitting
                                                         Multiple
                                                         Sclerosis.
------------------------------------------------------------------------
University of   5841 SOUTH   CHICAGO  IL         60637  A study of the
 Chicago         MARYLAND                                effects of
 Hospital        AVENUE                                  Alemtuzumab on
                                                         Surrogate
                                                         Markers of
                                                         Disease
                                                         Activity and
                                                         Repair using
                                                         Advanced MRI
                                                         measures in
                                                         Subjects with
                                                         Relapsing
                                                         Remitting
                                                         Multiple
                                                         Sclerosis.
------------------------------------------------------------------------
University of   5841 SOUTH   CHICAGO  IL         60637  A study of the
 Chicago         MARYLAND                                effects of
 Hospital        AVENUE                                  Alemtuzumab on
                                                         Surrogate
                                                         Markers of
                                                         Disease
                                                         Activity and
                                                         Repair using
                                                         Advanced MRI
                                                         measures in
                                                         Subjects with
                                                         Relapsing
                                                         Remitting
                                                         Multiple
                                                         Sclerosis.
------------------------------------------------------------------------
University of   5841 SOUTH   CHICAGO  IL         60637  A study of the
 Chicago         MARYLAND                                effects of
 Hospital        AVENUE                                  Alemtuzumab on
                                                         Surrogate
                                                         Markers of
                                                         Disease
                                                         Activity and
                                                         Repair using
                                                         Advanced MRI
                                                         measures in
                                                         Subjects with
                                                         Relapsing
                                                         Remitting
                                                         Multiple
                                                         Sclerosis.
------------------------------------------------------------------------
University of   5841 SOUTH   CHICAGO  IL         60637  A study of the
 Chicago         MARYLAND                                effects of
 Hospital        AVENUE                                  Alemtuzumab on
                                                         Surrogate
                                                         Markers of
                                                         Disease
                                                         Activity and
                                                         Repair using
                                                         Advanced MRI
                                                         measures in
                                                         Subjects with
                                                         Relapsing
                                                         Remitting
                                                         Multiple
                                                         Sclerosis.
------------------------------------------------------------------------
University of   5841 SOUTH   CHICAGO  IL         60637  A study of the
 Chicago         MARYLAND                                effects of
 Hospital        AVENUE                                  Alemtuzumab on
                                                         Surrogate
                                                         Markers of
                                                         Disease
                                                         Activity and
                                                         Repair using
                                                         Advanced MRI
                                                         measures in
                                                         Subjects with
                                                         Relapsing
                                                         Remitting
                                                         Multiple
                                                         Sclerosis.
------------------------------------------------------------------------
University of   5841 SOUTH   CHICAGO  IL         60637  A study of the
 Chicago         MARYLAND                                effects of
 Hospital        AVENUE                                  Alemtuzumab on
                                                         Surrogate
                                                         Markers of
                                                         Disease
                                                         Activity and
                                                         Repair using
                                                         Advanced MRI
                                                         measures in
                                                         Subjects with
                                                         Relapsing
                                                         Remitting
                                                         Multiple
                                                         Sclerosis.
------------------------------------------------------------------------
University of   5841 SOUTH   CHICAGO  IL         60637  A study of the
 Chicago         MARYLAND                                effects of
 Hospital        AVENUE                                  Alemtuzumab on
                                                         Surrogate
                                                         Markers of
                                                         Disease
                                                         Activity and
                                                         Repair using
                                                         Advanced MRI
                                                         measures in
                                                         Subjects with
                                                         Relapsing
                                                         Remitting
                                                         Multiple
                                                         Sclerosis.
------------------------------------------------------------------------
University of   5841 SOUTH   CHICAGO  IL         60637  A study of the
 Chicago         MARYLAND                                effects of
 Hospital        AVENUE                                  Alemtuzumab on
                                                         Surrogate
                                                         Markers of
                                                         Disease
                                                         Activity and
                                                         Repair using
                                                         Advanced MRI
                                                         measures in
                                                         Subjects with
                                                         Relapsing
                                                         Remitting
                                                         Multiple
                                                         Sclerosis.
------------------------------------------------------------------------
University of   5841 SOUTH   CHICAGO  IL         60637  A study of the
 Chicago         MARYLAND                                effects of
 Hospital        AVENUE                                  Alemtuzumab on
                                                         Surrogate
                                                         Markers of
                                                         Disease
                                                         Activity and
                                                         Repair using
                                                         Advanced MRI
                                                         measures in
                                                         Subjects with
                                                         Relapsing
                                                         Remitting
                                                         Multiple
                                                         Sclerosis.
------------------------------------------------------------------------
University of   5841 SOUTH   CHICAGO  IL         60637  A study of the
 Chicago         MARYLAND                                effects of
 Hospital        AVENUE                                  Alemtuzumab on
                                                         Surrogate
                                                         Markers of
                                                         Disease
                                                         Activity and
                                                         Repair using
                                                         Advanced MRI
                                                         measures in
                                                         Subjects with
                                                         Relapsing
                                                         Remitting
                                                         Multiple
                                                         Sclerosis.
------------------------------------------------------------------------
University of   5841 SOUTH   CHICAGO  IL         60637  A study of the
 Chicago         MARYLAND                                effects of
 Hospital        AVENUE                                  Alemtuzumab on
                                                         Surrogate
                                                         Markers of
                                                         Disease
                                                         Activity and
                                                         Repair using
                                                         Advanced MRI
                                                         measures in
                                                         Subjects with
                                                         Relapsing
                                                         Remitting
                                                         Multiple
                                                         Sclerosis.
------------------------------------------------------------------------
University of   5841 SOUTH   CHICAGO  IL         60637  A study of the
 Chicago         MARYLAND                                effects of
 Hospital        AVENUE                                  Alemtuzumab on
                                                         Surrogate
                                                         Markers of
                                                         Disease
                                                         Activity and
                                                         Repair using
                                                         Advanced MRI
                                                         measures in
                                                         Subjects with
                                                         Relapsing
                                                         Remitting
                                                         Multiple
                                                         Sclerosis.
------------------------------------------------------------------------
Keck Hospital   1500 SAN     LOS      CA         90033  Detection of
 of USC          PABLO        ANGELE                     early end-organ
                 STREET       S                          damage by
                                                         endothelial
                                                         dysfunction
                                                         with reactive
                                                         hyperemia-
                                                         digital
                                                         peripheral
                                                         arterial
                                                         tonometry in
                                                         patients with
                                                         Fabry disease
------------------------------------------------------------------------
University of   619 SOUTH    BIRMING  AL         35233  Improved
 Alabama         19TH         HAM                        Detection,
 Hospital        STREET                                  Diagnosis, and
                                                         Management of
                                                         Fabry Disease
                                                         through Serial
                                                         Ophthalmic
                                                         Documentation
                                                         and Tear Fluid
                                                         Analysis
------------------------------------------------------------------------
University of   5841 SOUTH   CHICAGO  IL         60637  A study of the
 Chicago         MARYLAND                                effects of
 Hospital        AVENUE                                  Alemtuzumab on
                                                         Surrogate
                                                         Markers of
                                                         Disease
                                                         Activity and
                                                         Repair using
                                                         Advanced MRI
                                                         measures in
                                                         Subjects with
                                                         Relapsing
                                                         Remitting
                                                         Multiple
                                                         Sclerosis.
------------------------------------------------------------------------
University of   5841 SOUTH   CHICAGO  IL         60637  A study of the
 Chicago         MARYLAND                                effects of
 Hospital        AVENUE                                  Alemtuzumab on
                                                         Surrogate
                                                         Markers of
                                                         Disease
                                                         Activity and
                                                         Repair using
                                                         Advanced MRI
                                                         measures in
                                                         Subjects with
                                                         Relapsing
                                                         Remitting
                                                         Multiple
                                                         Sclerosis.
------------------------------------------------------------------------
Brigham and     75 FRANCIS   BOSTON   MA         02115  Effects of an
 Womens          STREET                                  Intensive
 Hospital                                                Intervention on
                                                         Medication
                                                         Adherence,
                                                         Glycemic
                                                         Control, and
                                                         Readmission
                                                         Rates in
                                                         Patients with
                                                         Type 2 Diabetes
------------------------------------------------------------------------
University of   2            SEATTLE  WA         98195  FLuctuation
 Washington                                              Reduction With
                                                         Insulin and GLP-
                                                         1 Added
                                                         Together (FLAT-
                                                         SUGAR)
------------------------------------------------------------------------
Beth Israel     330          BOSTON   MA         02215  Simplification
 Deaconess       BROOKLINE                               of diabetes
 Medical         AVENUE                                  regimen in
 Center                                                  elderly
                                                         patients using
                                                         glargine
------------------------------------------------------------------------
Dana-Farber     450          BOSTON   MA         02215  Phase I Study of
 Cancer          BROOKLINE                               Plerixafor
 Institute       AVE                                     (AMD3100) and
                                                         Bevacizumab for
                                                         recurrent high-
                                                         grade glioma
------------------------------------------------------------------------
Dana-Farber     450          BOSTON   MA         02215  Phase I/II Trial
 Cancer          BROOKLINE                               of Combination
 Institute       AVE                                     AMD3100 and
                                                         Bortezomib in
                                                         Relapsed or
                                                         Relapsed/
                                                         Refractory
                                                         Multiple
                                                         Myeloma
------------------------------------------------------------------------
Dana-Farber     450          BOSTON   MA         02215  Phase I/II Trial
 Cancer          BROOKLINE                               of Combination
 Institute       AVE                                     AMD3100 and
                                                         Bortezomib in
                                                         Relapsed or
                                                         Relapsed/
                                                         Refractory
                                                         Multiple
                                                         Myeloma
------------------------------------------------------------------------
Dana-Farber     450          BOSTON   MA         02215  Taxotere Plus
 Cancer          BROOKLINE                               Six-Month
 Institute       AVE                                     Androgen
                                                         Suppression and
                                                         Radiation
                                                         Therapy vs Six-
                                                         Month Androgen
                                                         Suppression and
                                                         Radiation
                                                         Therapy for
                                                         Patients with
                                                         High-Risk
                                                         Localized or
                                                         Locally
                                                         Advanced
                                                         Prostate
                                                         Cancer: A
                                                         Randomized
                                                         Controlled
                                                         Trial
------------------------------------------------------------------------
UT MD Anderson  1515         HOUSTON  TX         77030  Phase I/II Study
 Cancer Center   HOLCOMBE                                of Plerixafor
                 BLVD                                    and Clofarabine
                                                         in Previously
                                                         Untreated Older
                                                         (>= 60 years)
                                                         Adult Patients
                                                         with Acute
                                                         Myelogenous
                                                         Leukemia (AML)
                                                         for Whom
                                                         Standard
                                                         Induction
                                                         Chemotherapy is
                                                         Unlikely to be
                                                         of Benefit
------------------------------------------------------------------------
UT MD Anderson  1515         HOUSTON  TX         77030  G-CSF and
 Cancer Center   HOLCOMBE                                Plerixafor with
                 BLVD                                    Sorafenib for
                                                         Acute
                                                         Myelogenous
                                                         Leukemia with
                                                         FLT3(ITD)
                                                         mutations
------------------------------------------------------------------------
UT MD Anderson  1515         HOUSTON  TX         77030  Phase I/II Study
 Cancer Center   HOLCOMBE                                of Plerixafor
                 BLVD                                    and Clofarabine
                                                         in Previously
                                                         Untreated Older
                                                         (>= 60 years)
                                                         Adult Patients
                                                         with Acute
                                                         Myelogenous
                                                         Leukemia (AML)
                                                         for Whom
                                                         Standard
                                                         Induction
                                                         Chemotherapy is
                                                         Unlikely to be
                                                         of Benefit
------------------------------------------------------------------------
UT MD Anderson  1515         HOUSTON  TX         77030  G-CSF and
 Cancer Center   HOLCOMBE                                Plerixafor with
                 BLVD                                    Sorafenib for
                                                         Acute
                                                         Myelogenous
                                                         Leukemia with
                                                         FLT3(ITD)
                                                         mutations
------------------------------------------------------------------------
Langley Porter  405          SAN      CA         94143  A Phase III
 Psychiatric     PARNASUS     FRANCI                     Trial of
 Institute                    SCO                        Irinotecan/5-FU/
                                                         Leucovorin or
                                                         Oxaliplatin/5-
                                                         FU/leucovorin
                                                         with
                                                         Bevacizumab, or
                                                         Cetuximab
                                                         (C225) or with
                                                         the Combination
                                                         of Bevacizumab
                                                         and Cetuximab
                                                         for Patients
                                                         with Untreated
                                                         Metastatic
                                                         Adenocarcinoma
                                                         of the Colon or
                                                         Rectum
------------------------------------------------------------------------
U of U          50 NORTH     SALT     UT         84132  Phase I/II Study
 Hospitals &     MEDICAL      LAKE                       of Low-Dose
 Clinic          DRIVE        CITY                       Oral
                                                         Clofarabine for
                                                         the treatment
                                                         of IPSS INT-1,
                                                         INT-2 or HIGH
                                                         Myelodysplastic
                                                         Syndromes
                                                         (dysplastic
                                                         type) Patients
                                                         who have failed
                                                         Hypomethylating
                                                         Therapy
------------------------------------------------------------------------
Lehigh Valley   2100 MACK    ALLENTO  PA         18105  A Multicenter,
 (.)             BLVD. 4TH    WN                         Randomized,
                 FLOOR                                   Controlled
                 FINANCE                                 Trial
                                                         Evaluating the
                                                         Safety,
                                                         Efficacy and
                                                         Cost-
                                                         Effectiveness
                                                         of Seprafilm
                                                         Adhesion
                                                         Barrier
                                                         Following
                                                         Cesarean
                                                         Section
------------------------------------------------------------------------
University of   5841 SOUTH   CHICAGO  IL         60637  A study of the
 Chicago         MARYLAND                                effects of
 Hospital        AVENUE                                  Alemtuzumab on
                                                         Surrogate
                                                         Markers of
                                                         Disease
                                                         Activity and
                                                         Repair using
                                                         Advanced MRI
                                                         measures in
                                                         Subjects with
                                                         Relapsing
                                                         Remitting
                                                         Multiple
                                                         Sclerosis.
------------------------------------------------------------------------
University of   5841 SOUTH   CHICAGO  IL         60637  A study of the
 Chicago         MARYLAND                                effects of
 Hospital        AVENUE                                  Alemtuzumab on
                                                         Surrogate
                                                         Markers of
                                                         Disease
                                                         Activity and
                                                         Repair using
                                                         Advanced MRI
                                                         measures in
                                                         Subjects with
                                                         Relapsing
                                                         Remitting
                                                         Multiple
                                                         Sclerosis.
------------------------------------------------------------------------
University of   5841 SOUTH   CHICAGO  IL         60637  A study of the
 Chicago         MARYLAND                                effects of
 Hospital        AVENUE                                  Alemtuzumab on
                                                         Surrogate
                                                         Markers of
                                                         Disease
                                                         Activity and
                                                         Repair using
                                                         Advanced MRI
                                                         measures in
                                                         Subjects with
                                                         Relapsing
                                                         Remitting
                                                         Multiple
                                                         Sclerosis.
------------------------------------------------------------------------
University of   5841 SOUTH   CHICAGO  IL         60637  A study of the
 Chicago         MARYLAND                                effects of
 Hospital        AVENUE                                  Alemtuzumab on
                                                         Surrogate
                                                         Markers of
                                                         Disease
                                                         Activity and
                                                         Repair using
                                                         Advanced MRI
                                                         measures in
                                                         Subjects with
                                                         Relapsing
                                                         Remitting
                                                         Multiple
                                                         Sclerosis.
------------------------------------------------------------------------
University of   5841 SOUTH   CHICAGO  IL         60637  A study of the
 Chicago         MARYLAND                                effects of
 Hospital        AVENUE                                  Alemtuzumab on
                                                         Surrogate
                                                         Markers of
                                                         Disease
                                                         Activity and
                                                         Repair using
                                                         Advanced MRI
                                                         measures in
                                                         Subjects with
                                                         Relapsing
                                                         Remitting
                                                         Multiple
                                                         Sclerosis.
------------------------------------------------------------------------
Emory           1364         ATLANTA  GA         30302  Do the Benefits
 University      CLIFTON                                 Outweigh the
 Hospital        ROAD                                    Risks?
                                                         Assessing
                                                         Patients'
                                                         Perceptions of
                                                         Newborn
                                                         Screening for
                                                         Lysosomal
                                                         Storage
                                                         Diseases
------------------------------------------------------------------------
Massachusetts   FRUIT        BOSTON   MA         02114  Neuroimaging
 General         STREET                                  Characteristics
 Hospital                                                in Fabry
                                                         Disease:
                                                         Quantitation of
                                                         CNS White
                                                         Matter Lesions
------------------------------------------------------------------------
Massachusetts   FRUIT        BOSTON   MA         02114  Neuroimaging
 General         STREET                                  Characteristics
 Hospital                                                in Fabry
                                                         Disease:
                                                         Quantitation of
                                                         CNS White
                                                         Matter Lesions
------------------------------------------------------------------------
Massachusetts   FRUIT        BOSTON   MA         02114  Neuroimaging
 General         STREET                                  Characteristics
 Hospital                                                in Fabry
                                                         Disease:
                                                         Quantitation of
                                                         CNS White
                                                         Matter Lesions
------------------------------------------------------------------------
University of   2            SEATTLE  WA         98195  Podocyturia: A
 Washington                                              Non-Invasive
                                                         Biomarker of
                                                         Fabry
                                                         Nephropathy
------------------------------------------------------------------------
University of   2            SEATTLE  WA         98195  Podocyturia: A
 Washington                                              Non-Invasive
                                                         Biomarker of
                                                         Fabry
                                                         Nephropathy
------------------------------------------------------------------------
University of   619 SOUTH    BIRMING  AL         35233  Cognitive
 Alabama         19TH         HAM                        Function
 Hospital        STREET                                  Assessment in
                                                         Fabry Disease:
                                                         A Pilot
                                                         Feasibility
                                                         Study
------------------------------------------------------------------------
University of   619 SOUTH    BIRMING  AL         35233  Multi-center,
 Alabama         19TH         HAM                        Open-label
 Hospital        STREET                                  Study of the
                                                         Safety and
                                                         Efficacy of
                                                         Control of
                                                         Proteinuria
                                                         with ACE
                                                         Inhibitors and
                                                         ARBS in
                                                         Patients with
                                                         Fabry Disease
                                                         Who Are
                                                         Receiving
                                                         Fabrazyme?: The
                                                         Fabrazyme? +
                                                         Arbs + ACE
                                                         inhibitors
                                                         Treatments
                                                         (FAACET) Study:
                                                         The FAACET
                                                         Study.
------------------------------------------------------------------------
Rochester       1425         ROCHEST  NY         14621  A Study
 General         PORTLAND     ER                         Evaluating
 Hospital        AVENUE                                  Acute Otitis
                                                         Media and
                                                         Nasopharyngeal
                                                         Colonization
                                                         Caused by
                                                         Streptococcus
                                                         pneumoniae in
                                                         Healthy
                                                         Children
------------------------------------------------------------------------
Dana-Farber     450          BOSTON   MA         02215  Randomized Phase
 Cancer          BROOKLINE                               II Study of
 Institute       AVE                                     FOLFOX +/-
                                                         Aflibercept in
                                                         metastatic
                                                         esophagogastric
                                                         cancer
------------------------------------------------------------------------
Dana-Farber     450          BOSTON   MA         02215  Randomized Phase
 Cancer          BROOKLINE                               II Study of
 Institute       AVE                                     FOLFOX +/-
                                                         Aflibercept in
                                                         metastatic
                                                         esophagogastric
                                                         cancer
------------------------------------------------------------------------
Dana-Farber     450          BOSTON   MA         02215  Randomized Phase
 Cancer          BROOKLINE                               II Study of
 Institute       AVE                                     FOLFOX +/-
                                                         Aflibercept in
                                                         metastatic
                                                         esophagogastric
                                                         cancer
------------------------------------------------------------------------
UT MD Anderson  1515         HOUSTON  TX         77030  A Randomized
 Cancer Center   HOLCOMBE                                Study of Once
                 BLVD                                    Daily
                                                         Fludarabine-
                                                         Clofarabine vs
                                                         Fludarabine
                                                         Alone Combined
                                                         with IV
                                                         Busulfan
                                                         Followed by
                                                         Allogeneic
                                                         Hemopoietic
                                                         Stem Cell
                                                         Transplantation
                                                         for AML and MDS
------------------------------------------------------------------------
UT MD Anderson  1515         HOUSTON  TX         77030  A Randomized
 Cancer Center   HOLCOMBE                                Study of Once
                 BLVD                                    Daily
                                                         Fludarabine-
                                                         Clofarabine vs
                                                         Fludarabine
                                                         Alone Combined
                                                         with IV
                                                         Busulfan
                                                         Followed by
                                                         Allogeneic
                                                         Hemopoietic
                                                         Stem Cell
                                                         Transplantation
                                                         for AML and MDS
------------------------------------------------------------------------
UT MD Anderson  1515         HOUSTON  TX         77030  A Randomized
 Cancer Center   HOLCOMBE                                Study of Once
                 BLVD                                    Daily
                                                         Fludarabine-
                                                         Clofarabine vs
                                                         Fludarabine
                                                         Alone Combined
                                                         with IV
                                                         Busulfan
                                                         Followed by
                                                         Allogeneic
                                                         Hemopoietic
                                                         Stem Cell
                                                         Transplantation
                                                         for AML and MDS
------------------------------------------------------------------------
UT MD Anderson  1515         HOUSTON  TX         77030  A Randomized
 Cancer Center   HOLCOMBE                                Study of Once
                 BLVD                                    Daily
                                                         Fludarabine-
                                                         Clofarabine vs
                                                         Fludarabine
                                                         Alone Combined
                                                         with IV
                                                         Busulfan
                                                         Followed by
                                                         Allogeneic
                                                         Hemopoie
------------------------------------------------------------------------
UT MD Anderson  1515         HOUSTON  TX         77030  A phase II study
 Cancer Center   HOLCOMBE                                of cabazitaxel
                 BLVD                                    with or without
                                                         carboplatin in
                                                         patients with
                                                         metastatic
                                                         castration-
                                                         resistant
                                                         prostate cancer
                                                         previously
                                                         treated with
                                                         docetaxel-based
                                                         therapy.
------------------------------------------------------------------------
UT MD Anderson  1515         HOUSTON  TX         77030  A phase II study
 Cancer Center   HOLCOMBE                                of cabazitaxel
                 BLVD                                    with or without
                                                         carboplatin in
                                                         patients with
                                                         metastatic
                                                         castration-
                                                         resistant
                                                         prostate cancer
                                                         previously
                                                         treated with
                                                         docetaxel-based
                                                         therapy.
------------------------------------------------------------------------
Memorial        1275 YORK    NEW      NY         10065  An Exploratory
 Hospital For    AVENUE       YORK                       Randomized
 Center                                                  Phase II
                                                         Multicenter
                                                         Trial of
                                                         Abiraterone
                                                         Acetate with or
                                                         without
                                                         Cabazitaxel in
                                                         Treatment of
                                                         Metastatic
                                                         Castration
                                                         Resistant
                                                         Prostate Cancer
------------------------------------------------------------------------
Brigham And     75 FRANCIS   BOSTON   MA         02115  Assessment of
 Womens          STREET                                  Aubagio?s
 Hospital                                                neuroprotective
                                                         effect on the
                                                         development of
                                                         T1 black holes
------------------------------------------------------------------------
Brigham And     75 FRANCIS   BOSTON   MA         02115  Assessment of
 Womens Hosp     STREET                                  Aubagio?s
                                                         neuroprotective
                                                         effect on the
                                                         development of
                                                         T1 black holes
------------------------------------------------------------------------
Brigham And     75 FRANCIS   BOSTON   MA         02115  Post-partum MRI
 Womens Hosp     STREET                                  Changes in
                                                         Women with
                                                         Multiple
                                                         Sclerosis.
------------------------------------------------------------------------
Brigham And     75 FRANCIS   BOSTON   MA         02115  Post-partum MRI
 Womens Hosp     STREET                                  Changes in
                                                         Women with
                                                         Multiple
                                                         Sclerosis.
------------------------------------------------------------------------
Brigham And     75 FRANCIS   BOSTON   MA         02115  Post-partum MRI
 Womens Hosp     STREET                                  Changes in
                                                         Women with
                                                         Multiple
                                                         Sclerosis.
------------------------------------------------------------------------
Keck Hospital   1500 SAN     LOS      CA         90033  Detection of
 of USC          PABLO        ANGELE                     early end-organ
                 STREET       S                          damage by
                                                         endothelial
                                                         dysfunction
                                                         with reactive
                                                         hyperemia-
                                                         digital
                                                         peripheral
                                                         arterial
                                                         tonometry in
                                                         patients with
                                                         Fabry Disease
------------------------------------------------------------------------
Vanderbilt      1211         NASHVIL  TN         37232  Innovation in
 University      MEDICAL      LE                         the timely
 Hospital        CENTER                                  diagnosis and
                 DRIVE                                   multidiscipinar
                                                         y treatment of
                                                         Fabry disease
------------------------------------------------------------------------
Emory           1364         ATLANTA  GA         30302  A Prospective,
 University      CLIFTON                                 Multicenter
 Hospital        ROAD                                    Study Of Fabry
                                                         Disease
                                                         Clinical and
                                                         Biochemical
                                                         Findings in
                                                         Young Pediatric
                                                         Patients (The
                                                         MOPPET Study)
------------------------------------------------------------------------
Emory           1364         ATLANTA  GA         30302  Reproductive
 University      CLIFTON                                 Fitness in
 Hospital        ROAD                                    Individuals
                                                         Affected by
                                                         Fabry Disease
                                                         (FIT)
------------------------------------------------------------------------
UCI Medical     101 CITY     ORANGE   CA         92868  Investigating
 Center (.)      DRIVE                                   Pompe
                 SOUTH                                   Prevalence in
                                                         NEuromuscular
                                                         Medicine
                                                         Academic
                                                         Practices
                                                         (IPANEMA Study)
------------------------------------------------------------------------
Massachusetts   FRUIT        BOSTON   MA         02114  The Fabry Pain
 General         STREET                                  Inventory:
 Hospital                                                Validation of a
                                                         New Clinical
                                                         Tool to
                                                         Comprehensively
                                                         Capture the
                                                         Fabry Pain
                                                         Experience
------------------------------------------------------------------------
University of   2            SEATTLE  WA         98195  Effects of Fabry
 Washington                                              Disease on
                                                         Myelination in
                                                         the In Vivo
                                                         Adult Human
                                                         Brain
------------------------------------------------------------------------
University of   619 SOUTH    BIRMING  AL         35233  Improved
 Alabama         19TH         HAM                        Detection,
 Hospital        STREET                                  Diagnosis, and
                                                         Management of
                                                         Fabry Disease
                                                         through Serial
                                                         Ophthalmic
                                                         Documentation
                                                         and Tear Fluid
                                                         Analysis
------------------------------------------------------------------------
Dana-Farber     450          BOSTON   MA         02215  Phase II Study
 Cancer          BROOKLINE                               of Clofarabine
 Institute       AVE                                     in Patients
                                                         with Recurrent
                                                         or Refractory
                                                         Langerhans Cell
                                                         Histiocytosis
------------------------------------------------------------------------
Dana-Farber     450          BOSTON   MA         02215  Phase I/II Trial
 Cancer          BROOKLINE                               of Combination
 Institute       AVE                                     AMD3100 and
                                                         Bortezomib in
                                                         Relapsed or
                                                         Relapsed/
                                                         Refractory
                                                         Multiple
                                                         Myeloma
------------------------------------------------------------------------
The Nebraska    DEWEY        OMAHA    NE         68198  Leukine
 Medical         AVENUE AT                               (sargramostim)
 Center          42ND                                    for Parkinson's
                                                         disease
------------------------------------------------------------------------
Charleston      501 MORRIS   CHARLES  WV         25326  A Phase II Trial
 Area Medical    STREET       TON                        of GM-CSF
                                                         Protein plus
                                                         Ipilimumab in
                                                         Patients with
                                                         Advanced
                                                         Melanoma (ECOG
                                                         1608)
------------------------------------------------------------------------
City of Hope    1500 EAST    DUARTE   CA         91010  Phase II Study
 National        DUARTE                                  of Clofarabine
 Medical         ROAD                                    and High-Dose
 Center                                                  Melphalan
                                                         Conditioning
                                                         Prior to
                                                         Allogeneic
                                                         Heamtopoietic
                                                         Cell
                                                         Transplantation
                                                         for
                                                         Myelodysplasia
------------------------------------------------------------------------
The Christ      2139 AUBURN  CINCINN  OH         45219  A Phase II Trial
 Hospital        AVENUE       ATI                        of GM-CSF
                                                         Protein plus
                                                         Ipilimumab in
                                                         Patients with
                                                         Advanced
                                                         Melanoma (ECOG
                                                         1608)
------------------------------------------------------------------------
Ohsu Hospital   3181 SAM     PORTLAN  OR         97239  A Phase I/II
 and Clinics     JACKSON      D                          Trial of
 (.)             PARK ROAD                               Concurrent
                                                         Chemohormonal
                                                         Therapy Using
                                                         Enzalutamide
                                                         (MDV-3100) and
                                                         Cabazitaxel in
                                                         Patients with
                                                         Metastatic
                                                         Castration
------------------------------------------------------------------------
Memorial        1275 YORK    NEW      NY         10065  Creation of a
 Hospital for    AVENUE       YORK                       registry of
 Cancer and                                              patients
 Allied                                                  treated on
 Diseases                                                TAX3503
 (101317743)
------------------------------------------------------------------------
Dana-Farber     450          BOSTON   MA         02215  Phase I/II Trial
 Cancer          BROOKLINE                               of Combination
 Institute (.)   AVE                                     AMD3100 and
                                                         Bortezomib in
                                                         Relapsed or
                                                         Relapsed/
                                                         Refractory
                                                         Multiple
                                                         Myeloma
------------------------------------------------------------------------
Memorial        1275 YORK    NEW      NY         10065  An Exploratory
 Hospital for    AVENUE       YORK                       Randomized
 Cancer and                                              Phase II
 Allied                                                  Multicenter
 Diseases                                                Trial of
 (101317743)                                             Abiraterone
                                                         Acetate with or
                                                         without
                                                         Cabazitaxel in
                                                         Treatment of
                                                         Metastatic
                                                         Castration
------------------------------------------------------------------------
UT MD Anderson  1515         HOUSTON  TX         77030  A Randomized
 Cancer Center   HOLCOMBE                                Phase 2 study
 (1083730964)    BLVD                                    to Evaluate the
                                                         Efficacy of
                                                         Rasburicase in
                                                         Patients at
                                                         Risk for TLS
                                                         During Two
                                                         Cycles of
                                                         Chemotherapy
------------------------------------------------------------------------
The Miriam      164 SUMMIT   PROVIDE  RI         02906  Aflibercept
 Hospital (.)    AVENUE       NCE                        Maintenance for
                                                         patients with
                                                         resected or
                                                         ablated
                                                         metastatic
                                                         colorectal
                                                         cancer
------------------------------------------------------------------------
Memorial        1275 YORK    NEW      NY         10065  An Exploratory
 Hospital for    AVENUE       YORK                       Randomized
 Cancer and                                              Phase II
 Allied                                                  Multicenter
 Diseases                                                Trial of
 (101317743)                                             Abiraterone
                                                         Acetate with or
                                                         without
                                                         Cabazitaxel in
                                                         Treatment of
                                                         Metastatic
                                                         Castration
------------------------------------------------------------------------
Memorial        1275 YORK    NEW      NY         10065  A Multi-center
 Hospital for    AVENUE       YORK                       Randomized
 Cancer and                                              Phase II Study
 Allied                                                  of the Impact
 Diseases                                                of CD34+ Cell
 (101317743)                                             Dose on
                                                         Progression-
                                                         free Survival
                                                         Following High-
                                                         Dose Therapy
------------------------------------------------------------------------
Dana-Farber     450          BOSTON   MA         02215  Phase I Study of
 Cancer          BROOKLINE                               Plerixafor
 Institute (.)   AVE                                     (AMD3100) and
                                                         Bevacizumab for
                                                         Recurrent High-
                                                         grade Glioma
------------------------------------------------------------------------
Emory           1364         ATLANTA  GA         30302  A Prospective,
 University      CLIFTON                                 Multicenter
 Hospital        ROAD                                    Study Of Fabry
 (1073592747)                                            Disease
                                                         Clinical and
                                                         Biochemical
                                                         Findings in
                                                         Young Pediatric
                                                         Patients (The
                                                         MOPPET Study)
------------------------------------------------------------------------
Vanderbilt      1211         NASHVIL  TN         37232  Innovation in
 University      MEDICAL      LE                         the timely
 Hospitals &     CENTER                                  diagnosis and
 Clinic (.)      DRIVE                                   multidiscipinar
                                                         y treatment of
                                                         Fabry disease
------------------------------------------------------------------------
Emory           1364         ATLANTA  GA         30302  Reproductive
 University      CLIFTON                                 Fitness in
 Hospital        ROAD                                    Individuals
 (1073592747)                                            Affected by
                                                         Fabry Disease
                                                         (FIT)
------------------------------------------------------------------------
Emory           1364         ATLANTA  GA         30302  Reproductive
 University      CLIFTON                                 Fitness in
 Hospital        ROAD                                    Individuals
 (1073592747)                                            Affected by
                                                         Fabry Disease
                                                         (FIT)
------------------------------------------------------------------------
Massachusetts   FRUIT        BOSTON   MA         02114  MGH Fabry
 General         STREET                                  Screening
 Hospital (.)                                            Initiative
------------------------------------------------------------------------
Emory           1364         ATLANTA  GA         30302  A Comparison of
 University      CLIFTON                                 Pharmacological
 Hospital        ROAD                                    vs.
 (1073592747)                                            Psychological
                                                         Interventions
                                                         to Improve
                                                         Adaptive
                                                         Function in
                                                         Fabry Patients
                                                         Undergoing
                                                         Enzyme Replace
------------------------------------------------------------------------
USC Norris      1441         LOS      CA         90033  Detection of
 Cancer          EASTLAKE     ANGELE                     early end-organ
 Hospital (.)    AVE          S                          damage by
                                                         endothelial
                                                         dysfunction
                                                         with reactive
                                                         hyperemia-
                                                         digital
                                                         peripheral
                                                         arterial
                                                         tonometry in
                                                         patients with
                                                         Fabry Disease.
------------------------------------------------------------------------
Emory           1364         ATLANTA  GA         30302  Online Social
 University      CLIFTON                                 Networking Use
 Hospital (.)    ROAD                                    Among
                                                         Individuals
                                                         Affected with
                                                         Lysosomal
                                                         Storage
                                                         Diseases:
                                                         ``Friend'' or
                                                         Foe?
------------------------------------------------------------------------
Massachusetts   FRUIT        BOSTON   MA         02114  Characterization
 General         STREET                                  and analysis of
 Hospital                                                pathophysiology
 (1114196961)                                            of the
                                                         gastrointestina
                                                         l complications
                                                         of Fabry
                                                         disease.
------------------------------------------------------------------------
Univ of MI      2301         ANN      MI         48105  A Phase II Study
 Hospitals &     COMMONWEAL   ARBOR                      of VEGF-Trap
 Hlth Ctrs       TH BLVD                                 plus Modified
 (1043488760)                                            FOLFOX 6 in
                                                         Previously
                                                         Untreated
                                                         Patients with
                                                         Metastatic
                                                         Colorectal
                                                         Cancer
------------------------------------------------------------------------
Cleveland       9500 EUCLID  CLEVELA  OH         44195  A Randomized,
 Clinic          AVENUE       ND                         Controlled,
 Hospital (.)                                            open-labeled
                                                         Clinical Trial
                                                         of
                                                         Thymoglobulin
                                                         Induction and
                                                         Extended Delay
                                                         of Calcineurin
                                                         Inhibitor
                                                         Therapy for
                                                         Rena
------------------------------------------------------------------------
Washington      110 IRVING   WASHING  DC         20010  Comparison of I-
 Hospital        STREET NW    TON                        124 and I-131
 Center                                                  Radiopharmacoki
 (1184638959)                                            netics in
                                                         Patients who
                                                         have Well-
                                                         differentiated
                                                         Thyroid Cancer
                                                         and have been
                                                         Prepared with
                                                         Radioactive
                                                         Iodine 124
------------------------------------------------------------------------
OHSU Hospital   3181 SAM     PORTLAN  OR         97239  A Phase I/II
 And Clinics     JACKSON      D                          Trial of
 (.)             PARK ROAD                               Concurrent
                                                         Chemohormonal
                                                         Therapy Using
                                                         Enzalutamide
                                                         (MDV-3100) and
                                                         Cabazitaxel in
                                                         Patients with
                                                         Metastatic
                                                         Castration
------------------------------------------------------------------------
City Of Hope    1500 EAST    DUARTE   CA         91010  Phase II Study
 National        DUARTE                                  of Clofarabine
 Medical         ROAD                                    and High-Dose
 Center                                                  Melphalan
 (103343529)                                             Conditioning
                                                         Prior to
                                                         Allogeneic
                                                         Heamtopoietic
                                                         Cell
                                                         Transplantation
                                                         for
                                                         Myelodysplasia
------------------------------------------------------------------------
Massachusetts   FRUIT        BOSTON   MA         02114  Phase II Study
 General         STREET                                  of Aflibercept
 Hospital (.)                                            in Patients
                                                         with Advanced,
                                                         Progressive
                                                         Carcinoid
                                                         Tumors
------------------------------------------------------------------------
Vanderbilt      1211         NASHVIL  TN         37232  Epidemiology of
 University      MEDICAL      LE                         Diabetes
 Hospitals &     CENTER                                  Interventions
 Clinic          DRIVE                                   and
 (1104202761)                                            Complications
------------------------------------------------------------------------
City Of Hope    1500 EAST    DUARTE   CA         91010  Phase II Study
 National        DUARTE                                  of Clofarabine
 Medical         ROAD                                    and High-Dose
 Center                                                  Melphalan
 (103343529)                                             Conditioning
                                                         Prior to
                                                         Allogeneic
                                                         Heamtopoietic
                                                         Cell
                                                         Transplantation
                                                         for
                                                         Myelodysplasia
------------------------------------------------------------------------
Dana-Farber     450          BOSTON   MA         02215  Phase II Study
 Cancer          BROOKLINE                               of Clofarabine
 Institute (.)   AVE                                     in Patients
                                                         with Recurrent
                                                         or Refractory
                                                         Langerhans Cell
                                                         Histiocytosis
------------------------------------------------------------------------
Univ Of Iowa    200 HAWKINS  IOWA     IA         52242  Epidemiology of
 Hosp & Clinic   DRIVE 1353   CITY                       Diabetes
 (.)             JCP                                     Interventions
                                                         and
                                                         Complications
------------------------------------------------------------------------
Univ of         ONE          COLUMBI  MO         65212  Epidemiology of
 Missouri        HOSPITAL     A                          Diabetes
 Health Care     DRIVE                                   Interventions
 (1033499256)                                            and
                                                         Complications
------------------------------------------------------------------------
University Of   1959 NE      SEATTLE  WA         98195  Epidemiology of
 Washington      PACIFIC ST                              Diabetes
 Med Ctr (.)                                             Interventions
                                                         and
                                                         Complications
------------------------------------------------------------------------
Yale-New Haven  20 YORK      NEW      CT         06504  Epidemiology of
 Hospital (.)    STREET       HAVEN                      Diabetes
                                                         Interventions
                                                         and
                                                         Complications
------------------------------------------------------------------------
University Of   22 SOUTH     BATLIMO  MD         21201  Epidemiology of
 Maryland Med    GREENE       RE                         Diabetes
 Sys             STREET                                  Interventions
 (1023304888)                                            and
                                                         Complications
------------------------------------------------------------------------
City Of Hope    1500 EAST    DUARTE   CA         91010  Phase II Study
 National        DUARTE                                  of Clofarabine
 Medical         ROAD                                    and High-Dose
 Center                                                  Melphalan
 (103343529)                                             Conditioning
                                                         Prior to
                                                         Allogeneic
                                                         Heamtopoietic
                                                         Cell
                                                         Transplantation
                                                         for
                                                         Myelodysplasia
------------------------------------------------------------------------
Charleston      501 MORRIS   CHARLES  WV         25326  A Phase II Trial
 Area Medical    STREET       TON                        of GM-CSF
 Center Inc.                                             Protein plus
 (1124248752)                                            Ipilimumab in
                                                         Patients with
                                                         Advanced
                                                         Melanoma (ECOG
                                                         1608)
------------------------------------------------------------------------
Yale-New Haven  20 YORK      NEW      CT         06504  Eliglustat
 Hospital        STREET       HAVEN                      Tatrate Named
 (1003142225)                                            Patient Program
------------------------------------------------------------------------
Memorial        1275 YORK    NEW      NY         10065  Safety and
 Hospital For    AVENUE       YORK                       Efficacy Trial
 Cancer And                                              of Escalation
 Allied                                                  of Plerixafor
 Diseases                                                for
 (101317743)                                             Mobilization of
                                                         CD34+
                                                         Hematopoietic
                                                         Progenitor
                                                         Cells and
                                                         Evaluation of
                                                         Globin Gene
                                                         Traits
------------------------------------------------------------------------
Dana-Farber     450          BOSTON   MA         02215  Phase II Study
 Cancer          BROOKLINE                               of Clofarabine
 Institute (.)   AVE                                     in Patients
                                                         with Recurrent
                                                         or Refractory
                                                         Langerhans Cell
                                                         Histiocytosis
------------------------------------------------------------------------
Massachusetts   FRUIT        BOSTON   MA         02114  Phase II Study
 General         STREET                                  of Aflibercept
 Hospital (.)                                            in Patients
                                                         with Advanced,
                                                         Progressive
                                                         Carcinoid
                                                         Tumors
------------------------------------------------------------------------
Univ Of MI      2301         ANN      MI         48105  A Phase II Study
 Hospitals &     COMMONWEAL   ARBOR                      of VEGF-Trap
 Hlth Ctrs       TH BLVD                                 plus Modified
 (1043488760)                                            FOLFOX 6 in
                                                         Previously
                                                         Untreated
                                                         Patients with
                                                         Metastatic
                                                         Colorectal
                                                         Cancer
------------------------------------------------------------------------
University      445 LENOX    BROOKLY  NY         11203  A Phase II Study
 Hospital Of     ROAD         N                          of VEGF-Trap
 Brooklyn (.)                                            plus Modified
                                                         FOLFOX 6 in
                                                         Previously
                                                         Untreated
                                                         Patients with
                                                         Metastatic
                                                         Colorectal
                                                         Cancer
------------------------------------------------------------------------
Washington      110 IRVING   WASHING  DC         20010  Comparison of I-
 Hospital        STREET NW    TON                        124 and I-131
 Center                                                  Radiopharmacoki
 (1184638959)                                            netics in
                                                         Patients who
                                                         have Well-
                                                         differentiated
                                                         Thyroid Cancer
                                                         and have been
                                                         Prepared with
                                                         Radioactive
                                                         Iodine 124
------------------------------------------------------------------------
University      445 LENOX    BROOKLY  NY         11203  A Phase II Study
 Hospital Of     ROAD         N                          of VEGF-Trap
 Brooklyn (.)                                            plus Modified
                                                         FOLFOX 6 in
                                                         Previously
                                                         Untreated
                                                         Patients with
                                                         Metastatic
                                                         Colorectal
                                                         Cancer
------------------------------------------------------------------------
Dana-Farber     450          BOSTON   MA         02215  Phase II Study
 Cancer          BROOKLINE                               of Clofarabine
 Institute (.)   AVE                                     in Patients
                                                         with Recurrent
                                                         or Refractory
                                                         Langerhans Cell
                                                         Histiocytosis
------------------------------------------------------------------------
OHSU Hospital   3181 SAM     PORTLAN  OR         97239  A Phase I/II
 And Clinics     JACKSON      D                          Trial of
 (.)             PARK ROAD                               Concurrent
                                                         Chemohormonal
                                                         Therapy Using
                                                         Enzalutamide
                                                         (MDV-3100) and
                                                         Cabazitaxel in
                                                         Patients with
                                                         Metastatic
                                                         Castration
------------------------------------------------------------------------
Univ Of MI      2301         ANN      MI         48105  A Phase II Study
 Hospitals &     COMMONWEAL   ARBOR                      of VEGF-Trap
 Hlth Ctrs       TH BLVD                                 plus Modified
 (1043488760)                                            FOLFOX 6 in
                                                         Previously
                                                         Untreated
                                                         Patients with
                                                         Metastatic
                                                         Colorectal
                                                         Cancer
------------------------------------------------------------------------
Charleston      501 MORRIS   CHARLES  WV         25326  A Phase II Trial
 Area Medical    STREET       TON                        of GM-CSF
 Center Inc.                                             Protein plus
 (1124248752)                                            Ipilimumab in
                                                         Patients with
                                                         Advanced
                                                         Melanoma (ECOG
                                                         1608)
------------------------------------------------------------------------
Univ Of MI      2301         ANN      MI         48105  A Phase II Study
 Hospitals &     COMMONWEAL   ARBOR                      of VEGF-Trap
 Hlth Ctrs       TH BLVD                                 plus Modified
 (1043488760)                                            FOLFOX 6 in
                                                         Previously
                                                         Untreated
                                                         Patients with
                                                         Metastatic
                                                         Colorectal
                                                         Cancer
------------------------------------------------------------------------
Yale-New Haven  20 YORK      NEW      CT         06504  Eliglustat
 Hospital        STREET       HAVEN                      Tatrate Named
 (1003142225)                                            Patient Program
------------------------------------------------------------------------
Memorial        1275 YORK    NEW      NY         10065  A Multi-center
 Hospital For    AVENUE       YORK                       Randomized
 Cancer And                                              Phase II Study
 Allied                                                  of the Impact
 Diseases                                                of CD34+ Cell
 (101317743)                                             Dose on
                                                         Progression-
                                                         free Survival
                                                         Following High-
                                                         Dose Therapy
                                                         and Autologous
                                                         Stem-cell
                                                         Rescue
------------------------------------------------------------------------
 Lucile         725 WELCH    PALO     CA         94304  AML08: A Phase
 Packard         ROAD         ALTO                       III randomized
 Childrens                                               trial of
 Hospital                                                clofarabine
 (1003929852)                                            plus cytarabine
                                                         versus
                                                         conventional
                                                         induction
                                                         therapy and of
                                                         natural killer
                                                         cell
                                                         transplantation
------------------------------------------------------------------------
City Of Hope    1500 EAST    DUARTE   CA         91010  Phase II Study
 National        DUARTE                                  of Clofarabine
 Medical         ROAD                                    and High-Dose
 Center                                                  Melphalan
 (103343529)                                             Conditioning
                                                         Prior to
                                                         Allogeneic
                                                         Heamtopoietic
                                                         Cell
                                                         Transplantation
                                                         for
                                                         Myelodysplasia
------------------------------------------------------------------------
City Of Hope    1500 EAST    DUARTE   CA         91010  Phase II Study
 National        DUARTE                                  of Clofarabine
 Medical         ROAD                                    and High-Dose
 Center                                                  Melphalan
 (103343529)                                             Conditioning
                                                         Prior to
                                                         Allogeneic
                                                         Heamtopoietic
                                                         Cell
                                                         Transplantation
                                                         for
                                                         Myelodysplasia
------------------------------------------------------------------------
Texas           6621 FANNIN  HOUSTON  TX         77030  Phase II Study
 Childrens                                               of Clofarabine
 Hospital (.)                                            in Patients
                                                         with Recurrent
                                                         or Refractory
                                                         Langerhans Cell
                                                         Histiocytosis
------------------------------------------------------------------------
Univ Of Iowa    200 HAWKINS  IOWA     IA         52242  Epidemiology of
 Hosp & Clinic   DRIVE 1353   CITY                       Diabetes
 (.)             JCP                                     Interventions
                                                         and
                                                         Complications
------------------------------------------------------------------------
Rainbow Babies  11100        CLEVELA  OH         44106  Epidemiology of
 & Childrens     EUCLID       ND                         Diabetes
 Hospital        AVENUE                                  Interventions
 (1013954395)                                            and
                                                         Complications
------------------------------------------------------------------------
Univ Of         ONE          COLUMBI  MO         65212  Epidemiology of
 Missouri        HOSPITAL     A                          Diabetes
 Health Care     DRIVE                                   Interventions
 (1033499256)                                            and
                                                         Complications
------------------------------------------------------------------------
University Of   1959 NE      SEATTLE  WA         98195  Epidemiology of
 Washington      PACIFIC ST                              Diabetes
 Med Ctr (.)                                             Interventions
                                                         and
                                                         Complications
------------------------------------------------------------------------
Yale-New Haven  20 YORK      NEW      CT         06504  Epidemiology of
 Hospital (.)    STREET       HAVEN                      Diabetes
                                                         Interventions
                                                         and
                                                         Complications
------------------------------------------------------------------------
Mayo Clinic     1216 SECOND  ROCHEST  MN         55905  Epidemiology of
 Hospital        STREET SW    ER                         Diabetes
 Rochester (.)                                           Interventions
                                                         and
                                                         Complications
------------------------------------------------------------------------
University Of   22 SOUTH     BATLIMO  MD         21201  Epidemiology of
 Maryland Med    GREENE       RE                         Diabetes
 Sys             STREET                                  Interventions
 (1023304888)                                            and
                                                         Complications
------------------------------------------------------------------------
Charleston      501 MORRIS   CHARLES  WV         25326  A Phase II Trial
 Area Medical    STREET       TON                        of GM-CSF
 Center Inc.                                             Protein plus
 (1124248752)                                            Ipilimumab in
                                                         Patients with
                                                         Advanced
                                                         Melanoma (ECOG
                                                         1608)
------------------------------------------------------------------------
Massachusetts   FRUIT        BOSTON   MA         02114  Phase II Study
 General         STREET                                  of Aflibercept
 Hospital (.)                                            in Patients
                                                         with Advanced,
                                                         Progressive
                                                         Carcinoid
                                                         Tumors
------------------------------------------------------------------------
Cleveland       9500 EUCLID  CLEVELA  OH         44195  A Randomized,
 Clinic          AVENUE       ND                         Controlled,
 Hospital (.)                                            open-labeled
                                                         Clinical Trial
                                                         of
                                                         Thymoglobulin
                                                         Induction and
                                                         Extended Delay
                                                         of Calcineurin
                                                         Inhibitor
                                                         Therapy for
                                                         Renal Failure
------------------------------------------------------------------------
Washington      110 IRVING   WASHING  DC         20010  Comparison of I-
 Hospital        STREET NW    TON                        124 and I-131
 Center                                                  Radiopharmacoki
 (1184638959)                                            netics in
                                                         Patients who
                                                         have Well-
                                                         differentiated
                                                         Thyroid Cancer
                                                         and have been
                                                         Prepared with
                                                         Radioactive
                                                         Iodine 124
------------------------------------------------------------------------
City Of Hope    1500 EAST    DUARTE   CA         91010  Phase II Study
 National        DUARTE                                  of Clofarabine
 Medical         ROAD                                    and High-Dose
 Center                                                  Melphalan
 (103343529)                                             Conditioning
                                                         Prior to
                                                         Allogeneic
                                                         Heamtopoietic
                                                         Cell
                                                         Transplantation
                                                         for
                                                         Myelodysplasia
------------------------------------------------------------------------
Memorial        1275 YORK    NEW      NY         10065  Safety and
 Hospital For    AVENUE       YORK                       Efficacy Trial
 Cancer And                                              of Escalation
 Allied                                                  of Plerixafor
 Diseases                                                for
 (101317743)                                             Mobilization of
                                                         CD34+
                                                         Hematopoietic
                                                         Progenitor
                                                         Cells and
                                                         Evaluation of
                                                         Globin Gene
                                                         Traits
------------------------------------------------------------------------
Cleveland       9500 EUCLID  CLEVELA  OH         44195  A Randomized,
 Clinic          AVENUE       ND                         Controlled,
 Hospital (.)                                            open-labeled
                                                         Clinical Trial
                                                         of
                                                         Thymoglobulin
                                                         Induction and
                                                         Extended Delay
                                                         of Calcineurin
                                                         Inhibitor
                                                         Therapy for
                                                         Renal Failure
------------------------------------------------------------------------
Charleston      501 MORRIS   CHARLES  WV         25326  A Phase II Trial
 Area Medical    STREET       TON                        of GM-CSF
 Center Inc.                                             Protein plus
 (1124248752)                                            Ipilimumab in
                                                         Patients with
                                                         Advanced
                                                         Melanoma (ECOG
                                                         1608)
------------------------------------------------------------------------
City Of Hope    1500 EAST    DUARTE   CA         91010  Phase II Study
 National        DUARTE                                  of Clofarabine
 Medical         ROAD                                    and High-Dose
 Center                                                  Melphalan
 (103343529)                                             Conditioning
                                                         Prior to
                                                         Allogeneic
                                                         Heamtopoietic
                                                         Cell
                                                         Transplantation
                                                         for
                                                         Myelodysplasia
------------------------------------------------------------------------
Texas           6621 FANNIN  HOUSTON  TX         77030  Phase II Study
 Childrens                                               of Clofarabine
 Hospital (.)                                            in Patients
                                                         with Recurrent
                                                         or Refractory
                                                         Langerhans Cell
                                                         Histiocytosis
------------------------------------------------------------------------
Massachusetts   FRUIT        BOSTON   MA         02114  Phase II Study
 General         STREET                                  of Aflibercept
 Hospital (.)                                            in Patients
                                                         with Advanced,
                                                         Progressive
                                                         Carcinoid
                                                         Tumors
------------------------------------------------------------------------
Cook Childrens  901 SEVENTH  FORT     TX         76104  AML08: A Phase
 Medical         AVENUE       WORTH                      III randomized
 Center                                                  trial of
 (1215907530)                                            clofarabine
                                                         plus cytarabine
                                                         versus
                                                         conventional
                                                         induction
                                                         therapy and of
                                                         natural killer
                                                         cell
                                                         transplantation
------------------------------------------------------------------------
Texas           6621 FANNIN  HOUSTON  TX         77030  Phase II Study
 Childrens                                               of Clofarabine
 Hospital (.)                                            in Patients
                                                         with Recurrent
                                                         or Refractory
                                                         Langerhans Cell
                                                         Histiocytosis
------------------------------------------------------------------------
Ohsu Hospital   3181 SAM     PORTLAN  OR         97239  A Phase I/II
 And Clinics     JACKSON      D                          Trial of
 (.)             PARK ROAD                               Concurrent
                                                         Chemohormonal
                                                         Therapy Using
                                                         Enzalutamide
                                                         (MDV-3100) and
                                                         Cabazitaxel in
                                                         Patients with
                                                         Metastatic
                                                         Castration
------------------------------------------------------------------------
Texas           6621 FANNIN  HOUSTON  TX         77030  Phase II Study
 Childrens                                               of Clofarabine
 Hospital (.)                                            in Patients
                                                         with Recurrent
                                                         or Refractory
                                                         Langerhans Cell
                                                         Histiocytosis
------------------------------------------------------------------------
Univ Of Mi      2301         ANN      MI         48105  A Phase II Study
 Hospitals &     COMMONWEAL   ARBOR                      of VEGF-Trap
 Hlth Ctrs       TH BLVD                                 plus Modified
 (1043488760)                                            FOLFOX 6 in
                                                         Previously
                                                         Untreated
                                                         Patients with
                                                         Metastatic
                                                         Colorectal
                                                         Cancer
------------------------------------------------------------------------
Univ Of MI      2301         ANN      MI         48105  A Phase II Study
 Hospitals &     COMMONWEAL   ARBOR                      of VEGF-Trap
 Hlth Ctrs       TH BLVD                                 plus Modified
 (1043488760)                                            FOLFOX 6 in
                                                         Previously
                                                         Untreated
                                                         Patients with
                                                         Metastatic
                                                         Colorectal
                                                         Cancer
------------------------------------------------------------------------
Lucile Packard  725 WELCH    PALO     CA         94304  AML08: A Phase
 Childrens       ROAD         ALTO                       III randomized
 Hospital                                                trial of
 (1003929852)                                            clofarabine
                                                         plus cytarabine
                                                         versus
                                                         conventional
                                                         induction
                                                         therapy and of
                                                         natural killer
                                                         cell
                                                         transplantation
------------------------------------------------------------------------
City Of Hope    1500 EAST    DUARTE   CA         91010  Phase II Study
 National        DUARTE                                  of Clofarabine
 Medical         ROAD                                    and High-Dose
 Center                                                  Melphalan
 (103343529)                                             Conditioning
                                                         Prior to
                                                         Allogeneic
                                                         Heamtopoietic
                                                         Cell
                                                         Transplantation
                                                         for
                                                         Myelodysplasia
------------------------------------------------------------------------
Emory           1364         ATLANTA  GA         30302  Enhancing Anti-
 University      CLIFTON                                 Myeloma Vaccine
 Hospital        ROAD                                    Response after
 (1073837167)                                            Autologous Stem
                                                         Cell
                                                         Transplantation
------------------------------------------------------------------------
Emory           1364         ATLANTA  GA         30302  MTA for :
 University      CLIFTON                                 Enhancing Anti-
 Hospital (.)    ROAD                                    Myeloma Vaccine
                                                         Response after
                                                         Autologous Stem
                                                         Cell Transplant
------------------------------------------------------------------------
Rochester       1425         ROCHEST  NY         14621  A Study
 General         PORTLAND     ER                         Evaluating
 Hospital (.)    AVENUE                                  Acute Otitis
                                                         Media and
                                                         Nasopharyngeal
                                                         Colonization
                                                         Caused by
                                                         Streptococcus
                                                         pneumoniae in
                                                         Healthy
                                                         Children
------------------------------------------------------------------------
Rochester       1425         ROCHEST  NY         14621  A Study
 General         PORTLAND     ER                         Evaluating
 Hospital (.)    AVENUE                                  Acute Otitis
                                                         Media and
                                                         Nasopharyngeal
                                                         Colonization
                                                         Caused by
                                                         Streptococcus
                                                         pneumoniae in
                                                         Healthy
                                                         Children
------------------------------------------------------------------------
Brigham And     75 FRANCIS   BOSTON   MA         02115  Assessment of
 Womens          STREET                                  Aubagio?s
 Hospital (.)                                            neuroprotective
                                                         effect on the
                                                         development of
                                                         T1 black holes
------------------------------------------------------------------------
Brigham And     75 FRANCIS   BOSTON   MA         02115  miRNA profiling
 Womens          STREET                                  in
 Hospital                                                Teriflunomide
 (1013935550)                                            (Aubagio)
                                                         treated
                                                         patients
------------------------------------------------------------------------
Langley Porter  405          SAN      CA         94143  Long-term
 Psychiatric     PARNASUS     FRANCI                     Management of
 Hosptial (.)                 SCO                        ?Younger,
                                                         Active?
                                                         Patients with
                                                         Pain from Early
                                                         Knee
                                                         Osteoarthritis
                                                         with Synvisc-
                                                         One (hylan G-F
                                                         20)
------------------------------------------------------------------------
University Of   1959 NE      SEATTLE  WA         98195  Fluctuation
 Washington      PACIFIC ST                              Reduction With
 Med Ctr (.)                                             Insulin and GLP-
                                                         1 Added
                                                         Together (FLAT-
                                                         SUGAR)
------------------------------------------------------------------------
University Of   1959 NE      SEATTLE  WA         98195  Fluctuation
 Washington      PACIFIC ST                              Reduction With
 Med Ctr (.)                                             Insulin and GLP-
                                                         1 Added
                                                         Together (FLAT-
                                                         UGAR)
------------------------------------------------------------------------
Cleveland       9500 EUCLID  CLEVELA  OH         44195  A Randomized,
 Clinic          AVENUE       ND                         Controlled,
 Hospital                                                open-labeled
 (1043549397)                                            Clinical Trial
                                                         of
                                                         Thymoglobulin
                                                         Induction and
                                                         Extended Delay
                                                         of Calcineurin
                                                         Inhibitor
                                                         Therapy for
                                                         Renal Failure
------------------------------------------------------------------------
Massachusetts   FRUIT        BOSTON   MA         02114  Phase II Study
 General         STREET                                  of Aflibercept
 Hospital                                                in Patients
 (1114196961)                                            with Advanced,
                                                         Progressive
                                                         Carcinoid
                                                         Tumors
------------------------------------------------------------------------
Charleston      501 MORRIS   CHARLES  WV         25326  A Phase II Trial
 Area Medical    STREET       TON                        of GM-CSF
 Center Inc.                                             Protein plus
 (1124248752)                                            Ipilimumab in
                                                         Patients with
                                                         Advanced
                                                         Melanoma (ECOG
                                                         1608)
------------------------------------------------------------------------
Cleveland       9500 EUCLID  CLEVELA  OH         44195  A Randomized,
 Clinic          AVENUE       ND                         Controlled,
 Hospital                                                open-labeled
 (1043549397)                                            Clinical Trial
                                                         of
                                                         Thymoglobulin
                                                         Induction and
                                                         Extended Delay
                                                         of Calcineurin
                                                         Inhibitor
                                                         Therapy for
                                                         Renal Failure
------------------------------------------------------------------------
Mount Sinai     ONE GUSTAVE  NEW      NY         10029  Phase II Study
 Hospital        L. LEVY      YORK                       of Clofarabine
 (1003063280)    PLACE                                   in Patients
                                                         with Recurrent
                                                         or Refractory
                                                         Langerhans Cell
                                                         Histiocytosis
------------------------------------------------------------------------
Mayo Clinic     1216 SECOND  ROCHEST  MN         55905  Epidemiology of
 Hospital        STREET SW    ER                         Diabetes
 Rochester (.)                                           Interventions
                                                         and
                                                         Complications
------------------------------------------------------------------------
Mayo Clinic     1216 SECOND  ROCHEST  MN         55905  Epidemiology of
 Hospital        STREET SW    ER                         Diabetes
 Rochester (.)                                           Interventions
                                                         and
                                                         Complications
------------------------------------------------------------------------
University Of   200 HAWKINS  IOWA     IA         52242  Epidemiology of
 Iowa Hosp &     DRIVE 1353   CITY                       Diabetes
 Clinics         JCP                                     Interventions
 (1326474149)                                            and
                                                         Complications
------------------------------------------------------------------------
University Of   200 HAWKINS  IOWA     IA         52242  Epidemiology of
 Iowa Hosp &     DRIVE 1353   CITY                       Diabetes
 Clinics         JCP                                     Interventions
 (1326474149)                                            and
                                                         Complications
------------------------------------------------------------------------
Univ Of         ONE          COLUMBI  MO         65212  Epidemiology of
 Missouri        HOSPITAL     A                          Diabetes
 Health Care     DRIVE                                   Interventions
 (1033499256)                                            and
                                                         Complications
------------------------------------------------------------------------
Univ Of         ONE          COLUMBI  MO         65212  Epidemiology of
 Missouri        HOSPITAL     A                          Diabetes
 Health Care     DRIVE                                   Interventions
 (1033499256)                                            and
                                                         Complications
------------------------------------------------------------------------
Vanderbilt      1211         NASHVIL  TN         37232  Epidemiology of
 University      MEDICAL      LE                         Diabetes
 Medical         CENTER                                  Interventions
 Center          DRIVE                                   and
 (1104202761)                                            Complications
------------------------------------------------------------------------
Yale-New Haven  20 YORK      NEW      CT         06504  Epidemiology of
 Hospital        STREET       HAVEN                      Diabetes
 (1003142225)                                            Interventions
                                                         and
                                                         Complications
------------------------------------------------------------------------
University Of   22 SOUTH     BATLIMO  MD         21201  Epidemiology of
 Maryland Med    GREENE       RE                         Diabetes
 Sys             STREET                                  Interventions
 (1023304888)                                            and
                                                         Complications
------------------------------------------------------------------------
University Of   22 SOUTH     BATLIMO  MD         21201  Epidemiology of
 Maryland Med    GREENE       RE                         Diabetes
 Sys             STREET                                  Interventions
 (1023304888)                                            and
                                                         Complications
------------------------------------------------------------------------
Cleveland       9500 EUCLID  CLEVELA  OH         44195  A Randomized,
 Clinic          AVENUE       ND                         Controlled,
 Hospital                                                open-labeled
 (1043549397)                                            Clinical Trial
                                                         of
                                                         Thymoglobulin
                                                         Induction and
                                                         Extended Delay
                                                         of Calcineurin
                                                         Inhibitor
                                                         Therapy for
                                                         Renal Failure
------------------------------------------------------------------------
Cleveland       9500 EUCLID  CLEVELA  OH         44195  A Randomized,
 Clinic          AVENUE       ND                         Controlled,
 Hospital                                                open-labeled
 (1043549397)                                            Clinical Trial
                                                         of
                                                         Thymoglobulin
                                                         Induction and
                                                         Extended Delay
                                                         of Calcineurin
                                                         Inhibitor
                                                         Therapy for
                                                         Renal Failure
------------------------------------------------------------------------
Massachusetts   FRUIT        BOSTON   MA         02114  Phase II Study
 General         STREET                                  of Aflibercept
 Hospital                                                in Patients
 (1114196961)                                            with Advanced,
                                                         Progressive
                                                         Carcinoid
                                                         Tumors
------------------------------------------------------------------------
Texas           6621 FANNIN  HOUSTON  TX         77030  Phase II Study
 Childrens                                               of Clofarabine
 Hospital                                                in Patients
 (1013283159)                                            with Recurrent
                                                         or Refractory
                                                         Langerhans Cell
                                                         Histiocytosis
------------------------------------------------------------------------
Charleston      501 MORRIS   CHARLES  WV         25326  A Phase II Trial
 Area Medical    STREET       TON                        of GM-CSF
 Center Inc.                                             Protein plus
 (1124248752)                                            Ipilimumab in
                                                         Patients with
                                                         Advanced
                                                         Melanoma (ECOG
                                                         1608)
------------------------------------------------------------------------
Methodist       7700 FLOYD   SAN      TX         78229  A Multi-center
 Hospital        CURL DRIVE   ANTONI                     Randomized
 (1124074273)                 O                          Phase II Study
                                                         of the Impact
                                                         of CD34+ Cell
                                                         Dose on
                                                         Progression-
                                                         free Survival
                                                         Following High-
                                                         Dose Therapy
                                                         and Autologous
                                                         Stem-cell
                                                         Rescue
------------------------------------------------------------------------
Texas           6621 FANNIN  HOUSTON  TX         77030  Phase II Study
 Childrens                                               of Clofarabine
 Hospital                                                in Patients
 (1013283159)                                            with Recurrent
                                                         or Refractory
                                                         Langerhans Cell
                                                         Histiocytosis
------------------------------------------------------------------------
Massachusetts   FRUIT        BOSTON   MA         02114  Phase II Study
 General         STREET                                  of Clofarabine
 Hospital                                                in Patients
 (1114196961)                                            with Recurrent
                                                         or Refractory
                                                         Langerhans Cell
                                                         Histiocytosis
------------------------------------------------------------------------
Cleveland       9500 EUCLID  CLEVELA  OH         44195  A Randomized,
 Clinic          AVENUE       ND                         Controlled,
 Hospital                                                open-labeled
 (1013392125)                                            Clinical Trial
                                                         of
                                                         Thymoglobulin
                                                         Induction and
                                                         Extended Delay
                                                         of Calcineurin
                                                         Inhibitor
                                                         Therapy for
                                                         Renal Failure
------------------------------------------------------------------------
Texas           6621 FANNIN  HOUSTON  TX         77030  Phase II Study
 Childrens                                               of Clofarabine
 Hospital                                                in Patients
 (1013283159)                                            with Recurrent
                                                         or Refractory
                                                         Langerhans Cell
                                                         Histiocytosis
------------------------------------------------------------------------
Arkansas        1 CHILDRENS  LITTLE   AR         72202  Phase II Study
 Childrens       WAY          ROCK                       of Clofarabine
 Hospital                                                in Patients
 (1134155831)                                            with Recurrent
                                                         or Refractory
                                                         Langerhans Cell
                                                         Histiocytosis
------------------------------------------------------------------------
Cleveland       9500 EUCLID  CLEVELA  OH         44195  A Randomized,
 Clinic          AVENUE       ND                         Controlled,
 Hospital                                                open-labeled
 (1013392125)                                            Clinical Trial
                                                         of
                                                         Thymoglobulin
                                                         Induction and
                                                         Extended Delay
                                                         of Calcineurin
                                                         Inhibitor
                                                         Therapy for
                                                         Renal Failure
------------------------------------------------------------------------
Cleveland       9500 EUCLID  CLEVELA  OH         44195  A Randomized,
 Clinic          AVENUE       ND                         Controlled,
 Hospital                                                open-labeled
 (1013392125)                                            Clinical Trial
                                                         of
                                                         Thymoglobulin
                                                         Induction and
                                                         Extended Delay
                                                         of Calcineurin
                                                         Inhibitor
                                                         Therapy for
                                                         Renal Failure
------------------------------------------------------------------------
Texas           6621 FANNIN  HOUSTON  TX         77030  Phase II Study
 Childrens                                               of Clofarabine
 Hospital                                                in Patients
 (1013283159)                                            with Recurrent
                                                         or Refractory
                                                         Langerhans Cell
                                                         Histiocytosis
------------------------------------------------------------------------
Texas           6621 FANNIN  HOUSTON  TX         77030  Phase II Study
 Childrens                                               of Clofarabine
 Hospital                                                in Patients
 (1013283159)                                            with Recurrent
                                                         or Refractory
                                                         Langerhans Cell
                                                         Histiocytosis
------------------------------------------------------------------------
Charleston      501 MORRIS   CHARLES  WV         25326  A Phase II Trial
 Area Medical    STREET       TON                        of GM-CSF
 Center Inc.                                             Protein plus
 (1124248752)                                            Ipilimumab in
                                                         Patients with
                                                         Advanced
                                                         Melanoma (ECOG
                                                         1608)
------------------------------------------------------------------------
Phoenix         1919 E.      PHOENIX  AZ         85016  Phase II Study
 Childrens       THOMAS                                  of Clofarabine
 Hospital        ROAD                                    in Patients
 (1023475506)                                            with Recurrent
                                                         or Refractory
                                                         Langerhans Cell
                                                         Histiocytosis
------------------------------------------------------------------------
Texas           6621 FANNIN  HOUSTON  TX         77030  Phase II Study
 Childrens                                               of Clofarabine
 Hospital                                                in Patients
 (1013283159)                                            with Recurrent
                                                         or Refractory
                                                         Langerhans Cell
                                                         Histiocytosis
------------------------------------------------------------------------
Texas           6621 FANNIN  HOUSTON  TX         77030  Phase II Study
 Childrens                                               of Clofarabine
 Hospital                                                in Patients
 (1013283159)                                            with Recurrent
                                                         or Refractory
                                                         Langerhans Cell
                                                         Histiocytosis
------------------------------------------------------------------------
Texas           6621 FANNIN  HOUSTON  TX         77030  Phase II Study
 Childrens                                               of Clofarabine
 Hospital                                                in Patients
 (1013283159)                                            with Recurrent
                                                         or Refractory
                                                         Langerhans Cell
                                                         Histiocytosis
------------------------------------------------------------------------
Univ Of         ONE          COLUMBI  MO         65212  Epidemiology of
 Missouri        HOSPITAL     A                          Diabetes
 Health Care     DRIVE                                   Interventions
 (1033499256)                                            and
                                                         Complications
------------------------------------------------------------------------
Univ Of         ONE          COLUMBI  MO         65212  Epidemiology of
 Missouri        HOSPITAL     A                          Diabetes
 Health Care     DRIVE                                   Interventions
 (1033499256)                                            and
                                                         Complications
------------------------------------------------------------------------
Yale-New Haven  20 YORK      NEW      CT         06504  Epidemiology of
 Hospital        STREET       HAVEN                      Diabetes
 (1003142225)                                            Interventions
                                                         and
                                                         Complications
------------------------------------------------------------------------
University Of   22 SOUTH     BATLIMO  MD         21201  Epidemiology of
 Maryland Med    GREENE       RE                         Diabetes
 Sys             STREET                                  Interventions
 (1023304888)                                            and
                                                         Complications
------------------------------------------------------------------------
University Of   22 SOUTH     BATLIMO  MD         21201  Epidemiology of
 Maryland Med    GREENE       RE                         Diabetes
 Sys             STREET                                  Interventions
 (1023304888)                                            and
                                                         Complications
------------------------------------------------------------------------
Massachusetts   FRUIT        BOSTON   MA         02114  Phase II Study
 General         STREET                                  of Clofarabine
 Hospital                                                in Patients
 (1114196961)                                            with Recurrent
                                                         or Refractory
                                                         Langerhans Cell
                                                         Histiocytosis
------------------------------------------------------------------------
Cleveland       9500 EUCLID  CLEVELA  OH         44195  A Randomized,
 Clinic          AVENUE       ND                         Controlled,
 Hospital                                                open-labeled
 (1013392125)                                            Clinical Trial
                                                         of
                                                         Thymoglobulin
                                                         Induction and
                                                         Extended Delay
                                                         of Calcineurin
                                                         Inhibitor
                                                         Therapy for
                                                         Renal Failure
------------------------------------------------------------------------
City Of Hope    1500 E.      DUARTE   CA         91010  Phase II Study
 National        DUARTE                                  of Clofarabine
 Medical Cnt     ROAD                                    and High-Dose
 (1033435292)                                            Melphalan
                                                         Conditioning
                                                         Prior to
                                                         Allogeneic
                                                         Heamtopoietic
                                                         Cell
                                                         Transplantation
                                                         for
                                                         Myelodysplasia
------------------------------------------------------------------------
Cleveland       9500 EUCLID  CLEVELA  OH         44195  A Randomized,
 Clinic          AVENUE       ND                         Controlled,
 Hospital                                                open-labeled
 (1013392125)                                            Clinical Trial
                                                         of
                                                         Thymoglobulin
                                                         Induction and
                                                         Extended Delay
                                                         of Calcineurin
                                                         Inhibitor
                                                         Therapy for
                                                         Renal Failure
------------------------------------------------------------------------
Charleston      501 MORRIS   CHARLES  WV         25326  A Phase II Trial
 Area Medical    STREET       TON                        of GM-CSF
 Center Inc.                                             Protein plus
 (1124248752)                                            Ipilimumab in
                                                         Patients with
                                                         Advanced
                                                         Melanoma (ECOG
                                                         1608)
------------------------------------------------------------------------
Phoenix         1919 E.      PHOENIX  AZ         85016  Phase II Study
 Childrens       THOMAS                                  of Clofarabine
 Hospital        ROAD                                    in Patients
 (1023475506)                                            with Recurrent
                                                         or Refractory
                                                         Langerhans Cell
                                                         Histiocytosis
------------------------------------------------------------------------
Mount Sinai     ONE GUSTAVE  NEW      NY         10029  Clinical Trial
 Hospital (.)    L. LEVY      YORK                       of a Rapidly
                 PLACE                                   Cycling, Non-
                                                         Cross Reactive
                                                         Regimen of
                                                         Approved
                                                         Therapeutic
                                                         Agents to Treat
                                                         Prostate Cancer
------------------------------------------------------------------------
Cleveland       9500 EUCLID  CLEVELA  OH         44195  A Randomized,
 Clinic          AVENUE       ND                         Controlled,
 Hospital                                                open-labeled
 (1013392125)                                            Clinical Trial
                                                         of
                                                         Thymoglobulin
                                                         Induction and
                                                         Extended Delay
                                                         of Calcineurin
                                                         Inhibitor
                                                         Therapy for
                                                         Renal Failure
------------------------------------------------------------------------
Cleveland       9500 EUCLID  CLEVELA  OH         44195  A Randomized,
 Clinic          AVENUE       ND                         Controlled,
 Hospital                                                open-labeled
 (1013392125)                                            Clinical Trial
                                                         of
                                                         Thymoglobulin
                                                         Induction and
                                                         Extended Delay
                                                         of Calcineurin
                                                         Inhibitor
                                                         Therapy for
                                                         Renal Failure
------------------------------------------------------------------------
Ohsu Hospital   3181 SAM     PORTLAN  OR         97239  A Phase I/II
 And Clinics     JACKSON      D                          Trial of
 (.)             PARK ROAD                               Concurrent
                                                         Chemohormonal
                                                         Therapy Using
                                                         Enzalutamide
                                                         (MDV-3100) and
                                                         Cabazitaxel in
                                                         Patients with
                                                         Metastatic
                                                         Castration
------------------------------------------------------------------------
Rochester       1425         ROCHEST  NY         14621  A Study
 General         PORTLAND     ER                         Evaluating
 Hospital        AVENUE                                  Acute Otitis
 (1023105376)                                            Media and
                                                         Nasopharyngeal
                                                         Colonization
                                                         Caused by
                                                         Streptococcus
                                                         pneumoniae in
                                                         Healthy
                                                         Children
------------------------------------------------------------------------
Rochester       1425         ROCHEST  NY         14621  A Study
 General         PORTLAND     ER                         Evaluating
 Hospital        AVENUE                                  Acute Otitis
 (1023105376)                                            Media and
                                                         Nasopharyngeal
                                                         Colonization
                                                         Caused by
                                                         Streptococcus
                                                         pneumoniae in
                                                         Healthy
                                                         Children
------------------------------------------------------------------------
Emory           1364         ATLANTA  GA         30302  Glargine U300
 University      CLIFTON                                 Hospital Trial:
 Hospital (.)    ROAD                                    A Randomized
                                                         Controlled
                                                         Trial Comparing
                                                         Glargine U300
                                                         and Glargine
                                                         U100 for the
                                                         Inpatient and
                                                         Post-Hospital
                                                         Discharge
------------------------------------------------------------------------
Cleveland       9500 EUCLID  CLEVELA  OH         44195  Investigating
 Clinic          AVENUE       ND                         the efficacy of
 Hospital (.)                                            Synvisc-One
                                                         (Hylan-GF 20
                                                         6ml ) as
                                                         adjunctive
                                                         therapy for
                                                         patients with
                                                         knee osteo-
                                                         arthritis or
                                                         requiring
                                                         physical
                                                         therapy
------------------------------------------------------------------------
Massachusetts   FRUIT        BOSTON   MA         02114  Enzyme
 General         STREET                                  Replacement
 Hospital                                                Therapy and
 (1114196961)                                            Podocyte
                                                         Function
------------------------------------------------------------------------
Massachusetts   FRUIT        BOSTON   MA         02114  KINDRED--Kidney
 General         STREET                                  Information
 Hospital                                                Network for
 (1114196961)                                            Disease
                                                         Research and
                                                         Education
------------------------------------------------------------------------
Tufts Medical   800          BOSTON   MA         02111  The Prevalence,
 Center (.)      WASHINGTON                              Morphology,
                 ST                                      Clinical Course
                                                         and Management
                                                         of Patients
                                                         with Anderson-
                                                         Fabry Disease
                                                         Identified
                                                         Among a Large
                                                         Adult
                                                         Population
------------------------------------------------------------------------
University Of   619 SOUTH    BIRMING  AL         35233  Teriflunomide as
 Alabama         19TH         HAM                        a disease
 Hospital (.)    STREET                                  modifying anti-
                                                         inflammatory
                                                         therapy for a
                                                         severe animal
                                                         model of
                                                         chronic
                                                         inflammatory
                                                         demyelinating
                                                         polyneuropathy
------------------------------------------------------------------------
Langley Porter  405          SAN      CA         94143  A Phase I Study
 Psychiatric     PARNASUS     FRANCI                     of Cabazitaxel,
 Hosptial                     SCO                        Mitoxanthrone,
 (1417115031)                                            and Prednisone
                                                         (CAMP) for
                                                         Patients with
                                                         Metastatic
                                                         Castration-
                                                         Resistant
                                                         Prostate Cancer
------------------------------------------------------------------------
Brigham And     75 FRANCIS   BOSTON   MA         02115  Post-partum MRI
 Womens          STREET                                  Changes in
 Hospital                                                Women with
 (1013935550)                                            Multiple
                                                         Sclerosis.
------------------------------------------------------------------------
University Of   1959 NE      SEATTLE  WA         98195  Establishing an
 Washington      PACIFIC ST                              in-vitro Model
 Med Ctr (.)                                             of Fabry
                                                         Podocytopathy
------------------------------------------------------------------------
UCI Medical     101 CITY     ORANGE   CA         92868  Investigating
 Center (.)      DRIVE                                   Pompe
                 SOUTH                                   Prevalence in
                                                         NEuromuscular
                                                         Medicine
                                                         Academic
                                                         Practices
                                                         (IPANEMA Study)
------------------------------------------------------------------------
UCI Medical     101 CITY     ORANGE   CA         92868  Safety and
 Center (.)      DRIVE                                   Effectiveness
                 SOUTH                                   of Resistance
                                                         exercise
                                                         training in
                                                         late onset
                                                         Pompe disease
                                                         patients--a
                                                         pilot study
------------------------------------------------------------------------
Emory           1364         ATLANTA  GA         30302  Do the Benefits
 University      CLIFTON                                 Outweigh the
 Hospital (.)    ROAD                                    Risks?
                                                         Assessing
                                                         Patients'
                                                         Perceptions of
                                                         Newborn
                                                         Screening for
                                                         Lysosomal
                                                         Storage
                                                         Diseases
------------------------------------------------------------------------
USC Norris      1441         LOS      CA         90033  Detection of
 Cancer          EASTLAKE     ANGELE                     early end-organ
 Hospital        AVE          S                          damage by
 (1104096577)                                            endothelial
                                                         dysfunction
                                                         with reactive
                                                         hyperemia-
                                                         digital
                                                         peripheral
                                                         arterial
                                                         tonometry in
                                                         patients with
                                                         Fabry Disease
------------------------------------------------------------------------
Emory           1364         ATLANTA  GA         30302  A Prospective,
 University      CLIFTON                                 Multicenter
 Hospital (.)    ROAD                                    Study Of Fabry
                                                         Disease
                                                         Clinical and
                                                         Biochemical
                                                         Findings in
                                                         Young Pediatric
                                                         Patients (The
                                                         MOPPET Study)
------------------------------------------------------------------------
University Of   1959 NE      SEATTLE  WA         98195  Establishing an
 Washington      PACIFIC ST                              in-vitro Model
 Med Ctr (.)                                             of Fabry
                                                         Podocytopathy
------------------------------------------------------------------------
Cleveland       9500 EUCLID  CLEVELA  OH         44195  A Randomized,
 Clinic          AVENUE       ND                         Controlled,
 Hospital                                                open-labeled
 (1013392125)                                            Clinical Trial
                                                         of
                                                         Thymoglobulin?
                                                         Induction and
                                                         Extended Delay
                                                         of Calcineurin
                                                         Inhibitor
                                                         Therapy for
                                                         Renal
                                                         Protection
                                                         after Liver
                                                         Transplantation
                                                         A Multi-Center
                                                         Study
------------------------------------------------------------------------
Cleveland       9500 EUCLID  CLEVELA  OH         44195  A Randomized,
 Clinic          AVENUE       ND                         Controlled,
 Hospital                                                open-labeled
 (1013392125)                                            Clinical Trial
                                                         of
                                                         Thymoglobulin?
                                                         Induction and
                                                         Extended Delay
                                                         of Calcineurin
                                                         Inhibitor
                                                         Therapy for
                                                         Renal
                                                         Protection
                                                         after Liver
                                                         Transplantation
                                                         A Multi-Center
                                                         Study
------------------------------------------------------------------------
Cleveland       9500 EUCLID  CLEVELA  OH         44195  A Randomized,
 Clinic          AVENUE       ND                         Controlled,
 Hospital                                                open-labeled
 (1013392125)                                            Clinical Trial
                                                         of
                                                         Thymoglobulin?
                                                         Induction and
                                                         Extended Delay
                                                         of Calcineurin
                                                         Inhibitor
                                                         Therapy for
                                                         Renal
                                                         Protection
                                                         after Liver
                                                         Transplantation
                                                         A Multi-Center
                                                         Study
------------------------------------------------------------------------
Cleveland       9500 EUCLID  CLEVELA  OH         44195  A Randomized,
 Clinic          AVENUE       ND                         Controlled,
 Hospital                                                open-labeled
 (1013392125)                                            Clinical Trial
                                                         of
                                                         Thymoglobulin?
                                                         Induction and
                                                         Extended Delay
                                                         of Calcineurin
                                                         Inhibitor
                                                         Therapy for
                                                         Renal
                                                         Protection
                                                         after Liver
                                                         Transplantation
                                                         A Multi-Center
                                                         Study
------------------------------------------------------------------------
OHSU Hospital   3181 SAM     PORTLAN  OR         97239  A Phase I/II
 and Clinics     JACKSON      D                          Trial of
 (1053454645)    PARK ROAD                               Concurrent
                                                         Chemohormonal
                                                         Therapy Using
                                                         Enzalutamide
                                                         (MDV-3100) and
                                                         Cabazitaxel in
                                                         Patients with
                                                         Metastatic
                                                         Castration
                                                         Resistant
                                                         Prostate Cancer
------------------------------------------------------------------------
OHSU Hospital   3181 SAM     PORTLAN  OR         97239  A Phase I/II
 and Clinics     JACKSON      D                          Trial of
 (1053454645)    PARK ROAD                               Concurrent
                                                         Chemohormonal
                                                         Therapy Using
                                                         Enzalutamide
                                                         (MDV-3100) and
                                                         Cabazitaxel in
                                                         Patients with
                                                         Metastatic
                                                         Castration
                                                         Resistant
                                                         Prostate Cancer
------------------------------------------------------------------------
OHSU Hospital   3181 SAM     PORTLAN  OR         97239  A Phase I/II
 and Clinics     JACKSON      D                          Trial of
 (1053454645)    PARK ROAD                               Concurrent
                                                         Chemohormonal
                                                         Therapy Using
                                                         Enzalutamide
                                                         (MDV-3100) and
                                                         Cabazitaxel in
                                                         Patients with
                                                         Metastatic
                                                         Castration
                                                         Resistant
                                                         Prostate Cancer
------------------------------------------------------------------------
Mount Sinai     FIRST        NEW      NY         10003  Gaucher
 Beth Israel     AVENUE AT    YORK                       Generation--Cog
 (1003052200)    16 STREET                               nition, Motor
                                                         Control,
                                                         Imaging and
                                                         Pathologic
                                                         Biomarkers in
                                                         GBA1 Mutation
                                                         Carriers
------------------------------------------------------------------------
University Of   1959 NE      SEATTLE  WA         98195  Fluctuation
 Washington      PACIFIC ST                              Reduction with
 Med Ctr (.)                                             Insulin and
                                                         GLP--1 Added
                                                         Together (FLAT-
                                                         SUGAR)
------------------------------------------------------------------------
University Of   1959 NE      SEATTLE  WA         98195  Fluctuation
 Washington      PACIFIC ST                              Reduction with
 Med Ctr (.)                                             Insulin and GLP-
                                                         1 Added
                                                         Together (FLAT-
                                                         SUGAR)
------------------------------------------------------------------------
Brigham And     75 FRANCIS   BOSTON   MA         02115  miRNA profiling
 Womens          STREET                                  in
 Hospital                                                Teriflunomide
 (1013935550)                                            (Aubagio)
                                                         treated
                                                         patients
------------------------------------------------------------------------
Massachusetts   FRUIT        BOSTON   MA         02114  Factors
 General         STREET                                  influencing
 Hospital                                                patient
 (1114196961)                                            preferences for
                                                         oral versus
                                                         intravenous
                                                         (IV) enzyme
                                                         replacement
                                                         medication.
------------------------------------------------------------------------
University Of   1959 NE      SEATTLE  WA         98195  Localization of
 Washington      PACIFIC ST                              Globotriaosylce
 Med Ctr (.)                                             ramide (GL3)
                                                         Inclusions in
                                                         Fabry Podocytes
------------------------------------------------------------------------
Emory           1364         ATLANTA  GA         30302  Online Social
 University      CLIFTON                                 Networking Use
 Hospital (.)    ROAD                                    Among
                                                         Individuals
                                                         Affected with
                                                         Lysosomal
                                                         Storage
                                                         Diseases:
                                                         ``Friend'' or
                                                         Foe?
------------------------------------------------------------------------
University Of   619 SOUTH    BIRMING  AL         35233  Comparative
 Alabama         19TH         HAM                        Proteomics and
 Hospital (.)    STREET                                  Lipidomics of
                                                         Exosomes
                                                         Isolated from
                                                         Serum and Urine
                                                         in Fabry
                                                         Disease
------------------------------------------------------------------------
Emory           1364         ATLANTA  GA         30302  Glargine U300
 University      CLIFTON                                 Hospital Trial:
 Hospital (.)    ROAD                                    A Randomized
                                                         Controlled
                                                         Trial Comparing
                                                         Glargine U300
                                                         and Glargine
                                                         U100 for the
                                                         Inpatient and
                                                         Post-Hospital
                                                         Discharge
                                                         Management of
                                                         Medicine and
                                                         Surgery
                                                         Patients with
                                                         Type 2 Diabetes
------------------------------------------------------------------------
UC Davis        2315         SACRAME  CA         95817  A Selective
 Medical         STOCKTON     NTO                        Frontline
 Center (.)      BLVD                                    Jevtana
                                                         Therapeutic
                                                         Pathway for
                                                         Castration-
                                                         Resistant
                                                         Prostate Cancer
                                                         with Integrated
                                                         Biomarkers
------------------------------------------------------------------------
Cleveland       9500 EUCLID  CLEVELA  OH         44195  A Study of
 Clinic          AVENUE       ND                         Hematopoietic
 Hospital                                                Stem Cell
 (1013392125)                                            Supermobilizati
                                                         on in Patients
                                                         with Lymphoma
------------------------------------------------------------------------
UH Cleveland    11100        CLEVELA  OH         44106  Epidemiology of
 Medical         EUCLID       ND                         Diabetes
 Center          AVENUE                                  Interventions
 (1013954395)                                            and
                                                         Complications
------------------------------------------------------------------------
UH Cleveland    11100        CLEVELA  OH         44106  Epidemiology of
 Medical         EUCLID       ND                         Diabetes
 Center          AVENUE                                  Interventions
 (1013954395)                                            and
                                                         Complications
------------------------------------------------------------------------
UH Cleveland    11100        CLEVELA  OH         44106  Epidemiology of
 Medical         EUCLID       ND                         Diabetes
 Center          AVENUE                                  Interventions
 (1013954395)                                            and
                                                         Complications
------------------------------------------------------------------------
Univ Of         ONE          COLUMBI  MO         65212  Epidemiology of
 Missouri        HOSPITAL     A                          Diabetes
 Health Care     DRIVE                                   Interventions
 (1033499256)                                            and
                                                         Complications
------------------------------------------------------------------------
Univ Of         ONE          COLUMBI  MO         65212  Epidemiology of
 Missouri        HOSPITAL     A                          Diabetes
 Health Care     DRIVE                                   Interventions
 (1033499256)                                            and
                                                         Complications
------------------------------------------------------------------------
Yale-New Haven  20 YORK      NEW      CT         06504  Epidemiology of
 Hospital        STREET       HAVEN                      Diabetes
 (1003142225)                                            Interventions
                                                         and
                                                         Complications
------------------------------------------------------------------------
University Of   22 SOUTH     BATLIMO  MD         21201  Epidemiology of
 Maryland Med    GREENE       RE                         Diabetes
 Sys             STREET                                  Interventions
 (1023304888)                                            and
                                                         Complications
------------------------------------------------------------------------
University Of   22 SOUTH     BATLIMO  MD         21201  Epidemiology of
 Maryland Med    GREENE       RE                         Diabetes
 Sys             STREET                                  Interventions
 (1023304888)                                            and
                                                         Complications
------------------------------------------------------------------------
University Of   22 SOUTH     BATLIMO  MD         21201  Epidemiology of
 Maryland Med    GREENE       RE                         Diabetes
 Sys             STREET                                  Interventions
 (1023304888)                                            and
                                                         Complications
------------------------------------------------------------------------
UT MD Anderson  1515         HOUSTON  TX         77030  A Dynamic
 Cancer Center   HOLCOMBE                                Allocation
 (1053755272)    BLVD                                    Modular
                                                         Sequential
                                                         Trial of
                                                         Approved and
                                                         Promising
                                                         Therapies in
                                                         Men with
                                                         Metastatic
                                                         Castration-
                                                         Resistant
                                                         Prostate Cancer
------------------------------------------------------------------------
OHSU Hospital   3181 SAM     PORTLAN  OR         97239  A Phase I/II
 And Clinics     JACKSON      D                          Trial of
 (1033650353)    PARK ROAD                               Concurrent
                                                         Chemohormonal
                                                         Therapy Using
                                                         Enzalutamide
                                                         (MDV-3100) and
                                                         Cabazitaxel in
                                                         Patients with
                                                         Metastatic
                                                         Castration
------------------------------------------------------------------------
UT MD Anderson  1515         HOUSTON  TX         77030  A Dynamic
 Cancer Center   HOLCOMBE                                Allocation
 (1053755272)    BLVD                                    Modular
                                                         Sequential
                                                         Trial of
                                                         Approved And
                                                         Promising
                                                         Therapies in
                                                         Men with
                                                         Metastatic
                                                         Castration-
                                                         Resistant
                                                         Prostate Cancer
------------------------------------------------------------------------
Charleston      501 MORRIS   CHARLES  WV         25326  A Phase II Trial
 Area Medical    STREET       TON                        of GM-CSF
 Center Inc.                                             Protein plus
 (1124248752)                                            Ipilimumab in
                                                         Patients with
                                                         Advanced
                                                         Melanoma (ECOG
                                                         1608)
------------------------------------------------------------------------
UT MD Anderson  1515         HOUSTON  TX         77030  A Dynamic
 Cancer Center   HOLCOMBE                                Allocation
 (1053755272)    BLVD                                    Modular
                                                         Sequential
                                                         Trial of
                                                         Approved And
                                                         Promising
                                                         Therapies in
                                                         Men with
                                                         Metastatic
                                                         Castration-
                                                         Resistant
                                                         Prostate Cancer
------------------------------------------------------------------------
OHSU Hospital   3181 SAM     PORTLAN  OR         97239  A Phase I/II
 And Clinics     JACKSON      D                          Trial of
 (1033650353)    PARK ROAD                               Concurrent
                                                         Chemohormonal
                                                         Therapy Using
                                                         Enzalutamide
                                                         (MDV-3100) and
                                                         Cabazitaxel in
                                                         Patients with
                                                         Metastatic
                                                         Castration-
                                                         Resistant
                                                         Prostate Cancer
------------------------------------------------------------------------
Univ Of         ONE          COLUMBI  MO         65212  Epidemiology of
 Missouri        HOSPITAL     A                          Diabetes
 Health Care     DRIVE                                   Interventions
 (1033499256)                                            and
                                                         Complications
------------------------------------------------------------------------
Yale-New Haven  20 YORK      NEW      CT         06504  Epidemiology of
 Hospital        STREET       HAVEN                      Diabetes
 (1003142225)                                            Interventions
                                                         and
                                                         Complications
------------------------------------------------------------------------
UH Cleveland    11100        CLEVELA  OH         44106  Epidemiology of
 Medical         EUCLID       ND                         Diabetes
 Center          AVENUE                                  Interventions
 (1013954395)                                            and
                                                         Complications
------------------------------------------------------------------------
University Of   22 SOUTH     BATLIMO  MD         21201  Epidemiology of
 Maryland Med    GREENE       RE                         Diabetes
 Sys             STREET                                  Interventions
 (1023304888)                                            and
                                                         Complications
------------------------------------------------------------------------
OHSU Hospital   3181 SAM     PORTLAN  OR         97239  A Phase I/II
 And Clinics     JACKSON      D                          Trial of
 (1033650353)    PARK ROAD                               Concurrent
                                                         Chemohormonal
                                                         Therapy Using
                                                         Enzalutamide
                                                         (MDV-3100) and
                                                         Cabazitaxel in
                                                         Patients with
                                                         Metastatic
                                                         Castration-
                                                         Resistant
                                                         Prostate Cancer
------------------------------------------------------------------------
Texas           6621 FANNIN  HOUSTON  TX         77030  Phase II Study
 Childrens                                               of Clofarabine
 Hospital                                                in Patients
 (1013283159)                                            with Recurrent
                                                         or Refractory
                                                         Langerhans Cell
                                                         Histiocytosis
------------------------------------------------------------------------
Massachusetts   FRUIT        BOSTON   MA         02114  Phase II Study
 General         STREET                                  of Clofarabine
 Hospital                                                in Patients
 (1114196961)                                            with Recurrent
                                                         or Refractory
                                                         Langerhans Cell
                                                         Histiocytosis
------------------------------------------------------------------------
Texas           6621 FANNIN  HOUSTON  TX         77030  Phase II Study
 Childrens                                               of Clofarabine
 Hospital                                                in Patients
 (1013283159)                                            with Recurrent
                                                         or Refractory
                                                         Langerhans Cell
                                                         Histiocytosis
------------------------------------------------------------------------
Childrens       4650 SUNSET  LOS      CA         90027  Phase II Study
 Hospital Los    BOULEVARD    ANGELE                     of Clofarabine
 Angeles                      S                          in Patients
 (1003102781)                                            with Recurrent
                                                         or Refractory
                                                         Langerhans Cell
                                                         Histiocytosis
------------------------------------------------------------------------
UT MD Anderson  1515         HOUSTON  TX         77030  A Dynamic
 Cancer Center   HOLCOMBE                                Allocation
 (1053755272)    BLVD                                    Modular
                                                         Sequential
                                                         Trial of
                                                         Approved and
                                                         Promising
                                                         Therapies in
                                                         Men with
                                                         Metastatic
                                                         Castration-
                                                         Resistant
                                                         Prostate Cancer
------------------------------------------------------------------------
OHSU Hospital   3181 SAM     PORTLAN  OR         97239  A Phase I/II
 And Clinics     JACKSON      D                          Trial of
 (1033650353)    PARK ROAD                               Concurrent
                                                         Chemohormonal
                                                         Therapy Using
                                                         Enzalutamide
                                                         (MDV-3100) and
                                                         Cabazitaxel in
                                                         Patients with
                                                         Metastatic
                                                         Castration-
                                                         Resistant
                                                         Prostate Cancer
------------------------------------------------------------------------
UT MD Anderson  1515         HOUSTON  TX         77030  A Dynamic
 Cancer Center   HOLCOMBE                                Allocation
 (1053755272)    BLVD                                    Modular
                                                         Sequential
                                                         Trial of
                                                         Approved and
                                                         Promising
                                                         Therapies in
                                                         Men with
                                                         Metastatic
                                                         Castration-
                                                         Resistant
                                                         Prostate Cancer
------------------------------------------------------------------------
Texas           6621 FANNIN  HOUSTON  TX         77030  Phase II Study
 Childrens                                               of Clofarabine
 Hospital                                                in Patients
 (1013283159)                                            with Recurrent
                                                         or Refractory
                                                         Langerhans Cell
                                                         Histiocytosis
------------------------------------------------------------------------
OHSU Hospital   3181 SAM     PORTLAN  OR         97239  A Phase I/II
 And Clinics     JACKSON      D                          Trial of
 (1033650353)    PARK ROAD                               Concurrent
                                                         Chemohormonal
                                                         Therapy Using
                                                         Enzalutamide
                                                         (MDV-3100) and
                                                         Cabazitaxel in
                                                         Patients with
                                                         Metastatic
                                                         Castration-
                                                         Resistant
                                                         Prostate Cancer
------------------------------------------------------------------------
UT MD Anderson  1515         HOUSTON  TX         77030  IST-1L-
 Cancer Center   HOLCOMBE                                Smoldering
 (1053755272)    BLVD                                    myeloma-PT-IV
------------------------------------------------------------------------
UT MD Anderson  1515         HOUSTON  TX         77030  SAR650984--Anti-
 Cancer Center   HOLCOMBE                                CD38 naked mAb--
 (1053755272)    BLVD                                    isatuximab
------------------------------------------------------------------------
UT MD Anderson  1515         HOUSTON  TX         77030  IST-1L-
 Cancer Center   HOLCOMBE                                Smoldering
 (1053755272)    BLVD                                    myeloma-PT-IV
------------------------------------------------------------------------
UT MD Anderson  1515         HOUSTON  TX         77030  IST-1L-
 Cancer Center   HOLCOMBE                                Smoldering
 (1053755272)    BLVD                                    myeloma-PT-IV
------------------------------------------------------------------------
Rochester       1425         ROCHEST  NY         14617  A Study
 General         PORTLAND     ER                         Evaluating
 Hospital        AVENUE                                  Acute Otitis
 (1023105376)                                            Media and
                                                         Nasopharyngeal
                                                         Colonization
                                                         Caused by
                                                         Streptococcus
                                                         pneumoniae in
                                                         Healthy
                                                         Children
------------------------------------------------------------------------
KFH-Hawaii      3288         HONOLUL  HI         96819  Efficacy of
 (1306928254)    MOANALUA     U                          Flublok study
                 ROAD
------------------------------------------------------------------------
KFH-Hawaii      3288         HONOLUL  HI         96819  Vaccine
 (1306928254)    MOANALUA     U                          effectiveness
                 ROAD                                    of Flublok 18-
                                                         64
------------------------------------------------------------------------
University of   855 WEST     CHARLOT  VA         22908  IRB-HSR#14386
 Virginia        MAIN         TESVIL
 Medical Cente   STREET       L
 (.)
------------------------------------------------------------------------
Tufts Medical   800          BOSTON   MA         02111  The Prevalence,
 Center          WASHINGTON                              Morphology,
 (1114162013)    ST                                      Clinical Course
                                                         and Management
                                                         of Patients
                                                         with Anderson-
                                                         Fabry Disease
                                                         Identified
                                                         Among a Large
                                                         Adult
                                                         Population
------------------------------------------------------------------------
Massachusetts   FRUIT        BOSTON   MA         02114  Characterization
 General         STREET                                  and analysis of
 Hospital                                                pathophysiology
 (1114196961)                                            of the
                                                         gastrointestina
                                                         l complications
                                                         of Fabry
                                                         disease.
------------------------------------------------------------------------
Cleveland       9500 EUCLID  CLEVELA  OH         44195  Biomarkers of
 Clinic          AVENUE       ND                         Disease
 Hospital                                                Heterogeneity
 (1013392125)                                            in Multiple
                                                         Sclerosis:
                                                         Phase II
------------------------------------------------------------------------
UCI Medical     101 THE      SOUTH    CA         92868  Investigating
 Center (.)      CITY DRIVE   ORANGE                     Pompe
                                                         Prevalence in
                                                         NEuromuscular
                                                         Medicine
                                                         Academic
                                                         Practices
                                                         (IPANEMA Study)
------------------------------------------------------------------------
Cleveland       9500 EUCLID  CLEVELA  OH         44195  A Randomized,
 Clinic          AVENUE       ND                         Controlled,
 Hospital                                                open-labeled
 (1013392125)                                            Clinical Trial
                                                         of
                                                         Thymoglobulin?
                                                         Induction and
                                                         Extended Delay
                                                         of Calcineurin
                                                         Inhibitor
                                                         Therapy for
                                                         Renal Failure
------------------------------------------------------------------------
Cleveland       9500 EUCLID  CLEVELA  OH         44195  A Randomized,
 Clinic          AVENUE       ND                         Controlled,
 Hospital                                                open-labeled
 (1013392125)                                            Clinical Trial
                                                         of
                                                         Thymoglobulin?
                                                         Induction and
                                                         Extended Delay
                                                         of Calcineurin
                                                         Inhibitor
                                                         Therapy for
                                                         Renal Failure
------------------------------------------------------------------------
Cleveland       9500 EUCLID  CLEVELA  OH         44195  A Randomized,
 Clinic          AVENUE       ND                         Controlled,
 Hospital                                                open-labeled
 (1013392125)                                            Clinical Trial
                                                         of
                                                         Thymoglobulin?
                                                         Induction and
                                                         Extended Delay
                                                         of Calcineurin
                                                         Inhibitor
                                                         Therapy for
                                                         Renal Failure
------------------------------------------------------------------------
OHSU Hospital   3181 SAM     PORTLAN  OR         97239  A Phase I/II
 And Clinics     JACKSON      D                          Trial of
 (1033650353)    PARK ROAD                               Concurrent
                                                         Chemohormonal
                                                         Therapy Using
                                                         Enzalutamide
                                                         (MDV-3100) and
                                                         Cabazitaxel in
                                                         Patients with
                                                         Metastatic
                                                         Castration-
                                                         Resistant
                                                         Prostate Cancer
------------------------------------------------------------------------
Mount Sinai     1ST AVENUE@   NEW     NY         10003  Gaucher
 Beth Israel     16TH         YORK                       Generation--Cog
 (1003052200)    STREET                                  nition, Motor
                                                         Control,
                                                         Imaging and
                                                         Pathologic
                                                         Biomarkers in
                                                         GBA1 Mutation
                                                         Carriers
------------------------------------------------------------------------
Mount Sinai     1ST AVENUE@  NEW      NY         10003  Gaucher
 Beth Israel     16TH         YORK                       Generation--Cog
 (1003052200)    STREET                                  nition, Motor
                                                         Control,
                                                         Imaging and
                                                         Pathologic
                                                         Biomarkers in
                                                         GBA1 Mutation
                                                         Carriers
------------------------------------------------------------------------
Emory           1364         ATLANTA  GA         30302  Newborn
 University      CLIFTON                                 Screening XLSD
 Hospital (.)    ROAD                                    Pilot Study
------------------------------------------------------------------------
University of   619 SOUTH    BIRMING  AL         35233  Comparative
 Alabama         19TH         HAM                        Proteomics and
 Hospital (.)    STREET                                  Lipidomics of
                                                         Exosomes
                                                         Isolated from
                                                         Serum and Urine
                                                         in Fabry
                                                         Disease
------------------------------------------------------------------------
UT MD Anderson  1515         HOUSTON  TX         77030  Interest of CT
 Cancer Center   HOLCOMBE                                Morphological
 (1053755272)    BLVD                                    Evaluation in
                                                         Patients with
                                                         Metastatic
                                                         Colorectal
                                                         Cancer Treated
                                                         with ZIV-
                                                         Aflibercept
------------------------------------------------------------------------
Brigham And     75 FRANCIS   BOSTON   MA         02115  New England
 Womens          STREET                                  Multiple
 Hospital                                                Sclerosis
 (1013935550)                                            Pregnancy
                                                         Registry (PREG-
                                                         MS)
------------------------------------------------------------------------
Brigham and     75 FRANCIS   BOSTON   MA         02115  New England
 Womens          STREET                                  Multiple
 Hospital                                                Sclerosis
 (1013935550)                                            Pregnancy
                                                         Registry (PREG-
                                                         MS)
------------------------------------------------------------------------
Brigham And     75 FRANCIS   BOSTON   MA         02115  New England
 Womens          STREET                                  Multiple
 Hospital                                                Sclerosis
 (1013935550)                                            Pregnancy
                                                         Registry (PREG-
                                                         MS)
------------------------------------------------------------------------
Univ Of Mi      2301         ANN      MI         48105  Regulatory B
 Hospitals &     COMMONWEAL   ARBOR                      Lymphocytes as
 Hlth Ctrs       TH BLVD                                 Central
 (1043488760)                                            Mediators of
                                                         the Therapeutic
                                                         Effects of
                                                         Teriflunomide
                                                         in MS
------------------------------------------------------------------------
Univ Of Mi      2301         ANN      MI         48105  Regulatory B
 Hospitals &     COMMONWEAL   ARBOR                      Lymphocytes as
 Hlth Ctrs       TH BLVD                                 Central
 (1043488760)                                            Mediators of
                                                         the Therapeutic
                                                         Effects of
                                                         Teriflunomide
                                                         in MS
------------------------------------------------------------------------
OHSU Hospital   3181 SAM     PORTLAN  OR         97239  Bright tongue
 and Clinics     JACKSON      D                          sign in Pompe
 (1033650353)    PARK ROAD                               disease:
                                                         sensitivity and
                                                         specificity
------------------------------------------------------------------------
OHSU Hospital   3181 SAM     PORTLAN  OR         97239  Bright tongue
 And Clinics     JACKSON      D                          sign in Pompe
 (1033650353)    PARK ROAD                               disease:
                                                         sensitivity and
                                                         specificity
------------------------------------------------------------------------
Brigham And     75 FRANCIS   BOSTON   MA         02115  miRNA profiling
 Womens          STREET                                  in
 Hospital                                                Teriflunomide
 (1013935550)                                            (Aubagio)
                                                         treated
                                                         patients
------------------------------------------------------------------------
Massachusetts   FRUIT        BOSTON   MA         02114  Enzyme
 General         STREET                                  Replacement
 Hospital                                                Therapy and
 (1114196961)                                            Podocyte
                                                         Function
------------------------------------------------------------------------
Massachusetts   FRUIT        BOSTON   MA         02114  KINDRED--Kidney
 General         STREET                                  Information
 Hospital                                                Network for
 (1114196961)                                            Disease
                                                         Research and
                                                         Education
------------------------------------------------------------------------
Emory           1364         ATLANTA  GA         30302  ThinkGenetic
 University      CLIFTON                                 LSD: A project
 Hospital (.)    ROAD                                    to identify
                                                         educational
                                                         gaps in the
                                                         informational
                                                         needs of
                                                         individuals
                                                         with Pompe,
                                                         Fabry, Gaucher,
                                                         Mucopolysacchar
                                                         ide Diseases
------------------------------------------------------------------------
Cedars-Sinai    8700         LOS      CA         90048  A Pilot
 Medical         BEVERLY      ANGELE                     Randomized
 Center (.)      BLVD.        S                          Study to Assess
                                                         the Effect and
                                                         Safety Profile
                                                         of
                                                         Thymoglobulin?
                                                         in Primary
                                                         Cardiac
                                                         Transplant
                                                         Recipients: A
                                                         12-month,
                                                         single center
                                                         study
------------------------------------------------------------------------
Massachusetts   FRUIT        BOSTON   MA         02114  Characterization
 General         STREET                                  and analysis of
 Hospital                                                pathophysiology
 (1114196961)                                            of the
                                                         gastrointestina
                                                         l complications
                                                         of Fabry
                                                         disease.
------------------------------------------------------------------------
University Of   619 SOUTH    BIRMING  AL         35233  Teriflunomide as
 Alabama         19TH         HAM                        a disease
 Hospital (.)    STREET                                  modifying anti-
                                                         inflammatory
                                                         therapy for a
                                                         severe animal
                                                         model of
                                                         chronic
                                                         inflammatory
                                                         demyelinating
                                                         polyneuropathy
------------------------------------------------------------------------
USC Norris      1441         LOS      CA         90033  Assessing the
 Cancer          EASTLAKE     ANGELE                     induction of
 Hospital        AVE          S                          long-term
 (1104096577)                                            immune
                                                         regulation
                                                         following
                                                         treatment with
                                                         Lemtrada?
                                                         (Alemtuzumab).
------------------------------------------------------------------------
USC Norris      1441         LOS      CA         90033  Assessing the
 Cancer          EASTLAKE     ANGELE                     induction of
 Hospital        AVE          S                          long-term
 (1104096577)                                            immune
                                                         regulation
                                                         following
                                                         treatment with
                                                         Lemtrada?
                                                         (Alemtuzumab).
------------------------------------------------------------------------
Emory           1364         ATLANTA  GA         30302  Functional
 University      CLIFTON                                 Resolution of
 Hospital (.)    ROAD                                    Multi-loci
                                                         Pathogenic
                                                         Variants and
                                                         VUSs in Pompe
                                                         Disease
------------------------------------------------------------------------

Prepared Statement of Giovanni Caforio, M.D., Chairman of the Board and 
         Chief Executive Officer, Bristol-Myers Squibb Company
    Chairman Grassley, Ranking Member Wyden, and members of the 
committee, thank you for the opportunity to be here today on behalf of 
the 24,000 employees at Bristol-Myers Squibb, who are working every day 
to improve the lives of patients with serious diseases. I look forward 
to working together to align incentives to ensure all Americans have 
access to the medicines they need.

    I am a physician who joined the biopharmaceutical industry 30 years 
ago because of the impact companies like Bristol-Myers Squibb--and the 
others represented here today--have on patients with serious diseases. 
We should all be proud that American companies lead our industry.

    Bristol-Myers Squibb researchers have contributed to the 
development of medicines that have reduced mortality from 
cardiovascular disease, helped transform HIV/AIDS into a chronic 
disease, and are now making significant progress in the treatment of 
cancer.

    Just 10 years ago, the idea of harnessing the immune system to 
treat cancer was viewed with great skepticism. But Bristol-Myers Squibb 
researchers saw the promise of the approach and ignited an era of 
scientific innovation that has changed survival expectations in 
multiple tumor types.

    Prior to the availability of Immuno-Oncology treatments, only 25 
percent of patients diagnosed with metastatic melanoma survived 1 year. 
Today, thanks to Immuno-Oncology therapies, this has increased to 74 
percent.

    The potential of this approach has also been seen in lung cancer, 
kidney cancer, and many other difficult-to-treat tumors. Patients with 
these diseases now have a chance for quality, long-term survival.

    But not all patients respond to current immunotherapies, so we must 
do more. We recently opened a new discovery facility dedicated to 
investigating Immuno-
Oncology resistance, and we continuously seek external innovation to 
augment our pipeline across multiple therapeutic areas. In this 
context, we recently announced our plan to acquire Celgene, a natural 
next step for our company. Our goal is to bring together the drive and 
dedication of two science-driven organizations to do even more for 
patients.

    As a physician, I recognize that medicines are only helpful if 
patients and health-care systems can afford them. We share the 
committee's concern with escalating health-care costs and believe that 
our responsibility to patients extends to ensuring they can access and 
afford our medicines.

    The average net pricing across our U.S. portfolio of medicines 
increased by 5 percent or less per year during the last 5 years. In 
2018, it did not increase and we anticipate the same in 2019.

    Despite this fact, we recognize that patients' out-of-pocket costs 
continue to increase. We believe it is possible to work together to 
realign incentives to ensure patients can afford medicines without 
stifling scientific innovation.

    So what are the solutions?

          We are supportive of the proposed rule aimed at reforming 
        the rebate system with a focus on what is best for patients.

          We need to ensure more generics are available whenever 
        permissible under our system, and applaud Congress and the 
        administration's success with speeding the approval of 
        generics.

          We support value-based purchasing arrangements that tie 
        payments to value. These models can reduce costs, improve 
        access and adherence, and contribute to better outcomes. We 
        applaud efforts by Health and Human Services and the Committee 
        to remove regulatory barriers and facilitate greater use of 
        these arrangements.

    We do not believe the U.S. should adopt policies that stifle 
innovation in other countries, which could reduce a patient's access to 
new medicines. Outside of the U.S., reimbursement of new medicines can 
often take more than two years. Our Opdivo and Yervoy regimen was first 
approved in September 2015 to treat metastatic melanoma in the U.S. 
Today, six of the 16 countries included in the International Price 
Index proposal do not provide access to this combination, which is now 
considered the standard of care for this cancer.

    This exemplifies why Bristol-Myers Squibb does not support HHS's 
proposed International Price Index Model for Medicare Part B drugs.

    I would like to leave you with a few thoughts.

    We are witnessing a historic era in biomedical innovation. But we 
must ensure patients have affordable access to these innovations.

    We recognize the need for change, and we are committed to working 
with Congress to ensure every patient can benefit from today's medical 
innovations.

    American research-based companies are leading the next wave of 
biomedical innovation to help patients whose diseases cannot be 
adequately treated with today's medicines. We should work to ensure 
policies that support and reward these investments.

    On behalf of my colleagues at Bristol-Myers Squibb, and the 
patients we serve, my sincere thanks for your time and attention today. 
I look forward to working together to implement real change that 
broadens access to innovative medicines for patients.

                                 ______
                                 
      Questions Submitted for the Record to Giovanni Caforio, M.D.
               Questions Submitted by Hon. Chuck Grassley
    Question. At the hearing, you testified that Bristol-Myers Squibb 
does not withhold samples from generic manufacturers in order to block 
generic versions of your drug from entering the market. You also 
expressed your support for the ``Creating and Restoring Equal Access to 
Equivalent Samples Act,'' also known as the CREATES Act.

    As you know, the FDA has a list on its website which identifies 
reference listed drug (RLD) access inquiries where brand manufacturers 
may have prevented generic companies from obtaining samples of products 
necessary to support FDA approval. Celgene is on this FDA list. 
According to your testimony, Bristol-Myers Squibb is in the process of 
acquiring Celgene.

    Are you aware that Celgene is on the FDA list and that Celgene had 
multiple access inquiries?

    Answer. Yes.

    Question. Will you ensure that Bristol-Myers Squibb/Celgene will 
not block access to samples once the Celgene acquisition is final?

    Answer. As Dr. Caforio testified at the hearing, BMS does not 
withhold samples from generic manufacturers in order to block generic 
versions of the drug from entering the market. BMS believes it is 
important to ensure generics are made available whenever that is 
permissible under our system, and supports the administration's focus 
on increasing the approval of generics. As part of that system, it is 
important that generic companies perform the needed testing to ensure 
product quality and patient safety. BMS cannot comment on Celgene's 
practices in this area, but once the transaction closes, BMS's 
practices with regard to generic samples will govern the combined 
portfolio.

    Question. The Department of Health and Human Services' proposed 
rule, ``Fraud and Abuse; Removal of Safe Harbor Protection for Rebates 
Involving Prescription Pharmaceuticals and Creation of New Safe Harbor 
Protection for Certain Point-of-Sale Reductions in Price on 
Prescription Pharmaceuticals and Certain Pharmacy Benefit Manager 
Service Fees,'' envisions that drug manufacturers will offer up-front 
discounts rather than the back-end rebates that are now commonly 
provided. Some observers argue that a 1996 court case called into 
question whether manufacturers could offer up-front discounts, 
resulting in today's rebate-based system. I've heard differing opinions 
as to whether the issues related to the initial court case are still 
relevant. If the HHS proposed rule is finalized, can you assure the 
committee that your company will offer up-front discounts? If not, why?

    Answer. BMS supports the HHS proposed rule to eliminate safe harbor 
protection for back-end rebates under Medicare Part D and the rule's 
objective to ensure that patients benefit from price reductions that 
BMS provides on its drugs. As the proposed rule notes, there is 
uncertainty as to the strategic behavior changes that will occur if the 
rule is enacted, and therefore uncertainty as to precise mechanisms 
that will be available to meet the objectives of the rule. However, 
there is some risk that manufacturers would have to defend themselves 
against antitrust litigation if they were to offer up-front discounts 
instead of rebates if the proposed rule were finalized. In particular, 
there may be risk of claims being crafted under the Robinson-Patman 
Act, 15 U.S.C. Sec. 13. Any such claims would have to meet significant 
substantive requirements and be subject to important statutory 
defenses. Nonetheless, even if meritless, Robinson-Patman claims can be 
expensive and time consuming for manufacturers to defend against.

    In light of the potential for antitrust litigation, BMS recommends 
that the committee consider how best to address this risk as it 
considers the HHS proposal. Congress, could, for example, enact 
legislation that immunizes from liability under the Robinson-Patman Act 
drug manufacturers who offer up-front discounting under Medicare Part D 
in accordance with the fraud and abuse safe harbor created by the HHS 
rule.

    Question. Please describe how you expect your company to respond to 
the HHS proposed rule to eliminate safe harbor protection for back-end 
rebates in Medicare Part D that is referenced above if it is finalized. 
Assuming you are confident that antitrust laws do not prevent your 
company from offering up-front discounts, specifically, do you envision 
that your company lowers the list price of a drug to the current after-
rebate net price, offer discounts equal to the current rebate amount, 
or a combination of both?

    Answer. BMS supports the HHS proposed rule to eliminate safe harbor 
protection for back-end rebates in Medicare Part D, and we believe it 
would lead to lower out-of-pocket costs. This question rightly supposes 
that the goals of the proposed rule could be achieved through lower 
list prices, negotiated discounts at the point-of-sale, or some 
combination of these two approaches. While it is unclear how Part D 
plans and PBMs will react to the proposed rule, at this time, BMS 
envisions that we would offer point-of-sale discounts to Part D plans 
equivalent on average to the current contracted rebate amount and will 
continue to assess the possibility of lowering list price on a product-
by-product basis. Our ability to lower list prices, however, is 
constrained by the fact that the HHS proposed rule does not apply to 
the commercial insurance market, where we anticipate back-end rebates 
to continue for the foreseeable future.

    Please also see the answer to the previous question.

    Question. To what extent are the back-end rebates your company 
currently offers contingent on the amount of market share realized for 
your drugs as a result of Part D plan formulary placement and other 
techniques?

    Answer. The back-end rebates BMS currently offers pursuant to its 
Medicare Part D agreements are not contingent on the amount of market 
share realized for any of BMS's drugs as a result of Part D plan 
formulary placement or any other performance requirement.

    Question. Please provide a breakdown of percentage of sales that go 
to each payer (including Medicare, Medicaid, private pay, other) and a 
similar percentage by volume of the total number of each drug compared 
to total volume. Please provide this data for the most recent year 
available.

    Answer. This information is not available publicly and is 
competitively sensitive.

    Question. Do your companies hire consultants or lobbyists to 
promote products at State Medicaid Pharmacy and Therapeutics 
Committees? To whom do you disclose advocacy activities surrounding 
State Medicaid programs, if at all?

    Answer. BMS does not hire consultants or lobbyists to promote its 
products at State Medicaid P&T Committees. BMS complies with the 
applicable lobbying laws across all 50 States, Puerto Rico, and the 
District of Columbia. Many States require engagement with its Medicaid 
officials to be reported. We disclose required lobbying activities to 
each State in accordance with the individual State lobbying disclosure 
and ethics laws.

    Question. Please describe how the costs of patient assistance 
programs are accounted for within your company's financial statements. 
Please also describe the types of market information, such as 
prescribing and use patterns that your company collects from different 
types of patient assistance programs and patient hub services.

    Answer. For purposes of responding to this request, BMS interprets 
``patient assistance programs'' and ``patient hub services'' as BMS 
programs or services supporting education, access and/or treatment 
adherence for eligible patients who are prescribed a BMS medicine. 
Costs associated with these programs are accounted for in our financial 
statements as marketing, selling and administrative expenses or gross-
to-net sales adjustments, depending on the type of assistance offered.

    Data captured through the administration of patient support 
programs allows our program administrators to validate information 
provided directly from patients and providers in support of the 
specific program(s) for which assistance is being requested. This data 
capture includes, but may not be limited to: (1) information that 
supports determination of patient eligibility; (2) validation of 
licensed provider/prescriber; (3) prescription related information 
necessary to execute patient assistance available through program(s) 
(i.e., dosage and units being prescribed/dispensed); and, (4) insurance 
information.

    Question. Please provide a list of all contributions since January 
1, 2014, that your company has made to any tax exempt organizations 
working on issues related to drugs within your product lines, including 
but not limited to patient groups, disease awareness groups, medical or 
professional societies, universities or hospitals, industry 
associations or leagues. For each contribution, please provide the name 
of the organization that received the donation, the date the donation 
was made, the amount of the donation, and a description of the purpose 
of the contribution (i.e., was the contribution for the general fund, a 
specific purpose to a specific program, or continuing medical 
education). Please also note whether the contribution was unrestricted 
or restricted; if it was restricted, please explain all restrictions. 
Finally, if your company maintains a foundation or other separate 
charitable arm, please provide the name of all such entities, and list 
all donations made from that entity or entities.

    Answer. BMS refers the committee to the Corporate Giving page on 
the BMS website (https://www.bms.com/about-us/responsibility/corporate-
giving.html). This page includes comprehensive information about BMS' 
Corporate Giving policies and practices. It also includes comprehensive 
lists of IME Grants, Charitable Donations and Corporate Giving for 
calendar years 2016, 2017 and 2018. These grants are made for a variety 
of appropriate purposes, not limited to issues related to drugs within 
the BMS product line.

    BMS supports the BMS Patient Assistance Foundation (BMSPAF), a non-
profit organization that helps patients in the United States who need 
temporary help obtaining various BMS medications. In 2018, BMS donated 
over $1 billion worth of BMS medicines to the BMSPAF, and the BMSPAF 
provided free medicine to more than 75,000 patients.

    BMS also supports the Bristol-Myers Squibb Foundation, a non-profit 
organization that promotes health equity and seeks to improve the 
health outcomes of populations disproportionately affected by serious 
diseases by strengthening health-care worker capacity, integrating 
medical care and community based support services, and mobilizing 
communities to fight against disease. BMS views the activities of the 
BMS Foundation as outside the scope of this question.

    Question. Pay for delay agreements cost consumers and taxpayers 
billions in higher drug costs every year. The FTC has gone after drug 
companies that enter into these settlements where the brand pays the 
generic company to keep its lower cost alternative off the market. I'm 
the lead Republican sponsor of S. 64, the ``Preserve Access to 
Affordable Generics and Biosimilars Act,'' which would help put an end 
to these deals.

    Do you agree that these pay-off agreements keep drug costs high for 
patients because they delay competition?

    Answer. BMS agrees that patent settlement agreements that have 
substantial payments going from innovators to generics, and are solely 
intended to delay competition, are anticompetitive.

    Question. Has your company ever entered into these kinds of 
settlements with a generic company?

    Answer. BMS has not entered into patent settlements that have 
substantial payments going from innovator to generics and are solely 
intended to delay competition.

    Question. Do you support the pay for delay bill?

    Answer. In general, the ability to settle patent litigation, like 
any litigation, reflects a balancing of considerations by the involved 
parties and often leads to earlier generic entry than patent 
expiration. The current system provides the government with the ability 
to monitor and review these settlements, and has worked well.

    With regard to S. 64, BMS supports the goals of the legislation but 
has objections to the legislation as currently drafted. For example, 
the legislation should be revised: (1) only to apply prospectively and 
not retroactively to agreements already entered into; (2) eliminate the 
presumption that all settlements are presumptively anticompetitive; (3) 
eliminate restrictions on the arguments companies would be permitted to 
advance to defend agreements; and (4) include ``exclusions'' for 
certain types of agreements, such as those containing exclusive 
licenses, to name a few. BMS would be happy to follow up and provide 
further details to the committee.
                           rebate traps/walls
    Question. I'm increasingly concerned about the effect of so-called 
``rebate traps'' or ``rebate walls'' on patients' access to quality, 
lower cost medicine. I understand there is ongoing litigation 
challenging these practices as anti-competitive.

    Does your company engage in the bundling of rebates over multiple 
products? If so, why? And what benefit does the consumer gain from 
that?

    Answer. BMS does not have any Medicare Part D or any other payer 
contracts with bundling of rebates.

    Question. Does your company view these practices as anticompetitive 
or harmful to patients' access to quality, lower cost medicine?

    Answer. BMS believes that clinical treatment decisions should be 
made by physicians in consultation with patients. As noted, BMS does 
not have bundled payer agreements and without insight to the specific 
terms of other manufacturers' bundling agreements, it is difficult to 
assess the impact on patient access and healthcare costs. BMS does not 
support agreements that create barriers to patients' access to quality, 
lower cost medicines.

    Question. If a policy were adopted to eliminate rebates, or to 
require that rebate savings be passed on to the consumer, would that in 
and of itself solve the issue of rebate ``traps'' and ``walls''? And 
would consumers benefit from such a policy?

    Answer. BMS believes that requiring PBMs and payers to pass 
manufacturer rebates on to patients has the potential to lower patient 
out-of-pocket costs, and therefore benefit consumers. However, it is 
unclear how payers will adjust their benefit plan designs in response 
to this change and whether it would completely solve the issue of 
rebate ``traps'' and ``walls.'' It is possible, for example, that in 
response to such changes, PBM and payer business models might evolve, 
and thus we recommend implementing safeguards to protect consumers' 
access to medicines.
                              drug pricing
    Question. When setting the list price of a drug, does your company 
consider regulatory costs or compliance? If so, how specifically do 
those factors affect the list price of a drug? Please provide at least 
one specific example, if applicable, from your current product 
portfolio.

    Answer. BMS does not consider these costs in setting list price.

    Question. When setting the list price of a drug, does your company 
consider the risk of liability or litigation? If so, how specifically 
do those factors affect the list price of a drug? Please provide at 
least one specific example, if applicable, from your current product 
portfolio.

    Answer. BMS does not consider the risk of liability or litigation 
in setting list price.

                                 ______
                                 
                Questions Submitted by Hon. Pat Roberts
    Question. What role do you see Value Based Arrangements (VBAs) 
playing in the effort to reduce prescription drug costs? What potential 
do these arrangements have to find the ``sweet spot'' between 
controlling costs to patients and encouraging innovation of new drugs?

    Answer. Manufacturers and payers have been participating in Value 
Based Agreements (VBAs) with increasing frequency. These agreements can 
potentially reduce overall health-care costs by reducing costs for 
medicines, and importantly, improving outcomes for patients and 
reducing overall health-care costs. Although there are many types of 
VBAs, and the goals and impact of these arrangements differ by specific 
medicines and therapeutic areas, we believe that as the sophistication 
of these payer and manufacturer arrangements increase, and the capture, 
integrity and timeliness of health-care data improves, these agreements 
will evolve to the ``sweet spot'' between controlling costs and 
encouraging the innovation of new medicines.

    Question. How can VBAs help lower what patients pay out-of-pocket?

    Answer. VBAs may lower patient out-of-pocket costs where, as a 
result of the VBA, the drug is placed on a preferred or lower formulary 
tier. In addition, as explained above, VBAs can potentially reduce 
overall healthcare costs, including patient out-of-pocket costs, by 
improving outcomes for patients through the reduction or elimination of 
the need for additional medicines and/or healthcare services.

    Question. Can Congress do more to allow for and encourage the use 
of VBAs?

    Answer. Yes. Congress can do more to allow for and encourage the 
use of VBAs. For example, Congress could adopt an exception to the 
Anti-Kickback Statute and enact measures to avoid unintended 
consequences under Medicaid price reporting.

                                 ______
                                 
                Questions Submitted by Hon. John Cornyn
    Question. We continue to hear that rebates negotiated off of the 
list price of a drug are both good and bad. Pharmacy benefit managers 
and plans have argued that rebates are used to lower premiums across 
the board and that it is the best way to seek a price concession on 
otherwise expensive drugs. Your industry argues that these payers are 
insisting on higher rebates that can only be achieved by raising list 
prices. But patients often lose under this system, with out of pocket 
costs being tied to list price. Insulin patients appear to be routinely 
impacted by this perversity in the system.

    Please explain to the committee how your company would reduce list 
prices if rebates were no longer a part of the equation?

    Answer. BMS supports the HHS proposed rule to eliminate safe harbor 
protection for back-end rebates in Medicare Part D, and we believe it 
would lead to lower out-of-pocket costs. The goals of the proposed rule 
could be achieved through lower list prices, negotiated discounts at 
the point-of-sale, or some combination of these two approaches. While 
it is unclear how Part D plans and PBMs will react to the proposed 
rule, at this time, BMS envisions that we would offer point-of-sale 
discounts to Part D plans equivalent on average to the contracted 
rebate amount and will continue to assess the possibility of lowering 
list prices on a product-by-product basis. BMS would likely follow a 
similar approach if back-end rebates were eliminated from the 
commercial insurance market.

    Question. What assurance can you provide that you would in fact 
lower your prices?

    Answer. Please see answer to previous question.

    Question. What actions should be taken to ensure that patients are 
actually seeing the benefits of lower out of pocket costs?

    Answer. In order to ensure that patients receive the full benefits 
of manufacturer discounts, we support the proposed rule's requirement 
that manufacturer discounts be passed on to patients at the point-of-
sale. In addition, we recommend implementing safeguards to protect 
consumers' access to medicines, to prevent increases in patients' out-
of-pocket costs, and to ensure that patients' costs at the point-of-
sale fully reflect manufacturer discounts.

    Question. If rebates are driving high list prices for drugs as drug 
manufacturers' claim, why do you think that Part B drugs, which have no 
PBM rebates, are also seeing significant price increases? Whose fault 
is that?

    Answer. The price increases for BMS Part B drugs have been largely 
in line with Medical CPI. We cannot comment on the Part B price 
increase practices of other manufacturers.

                                 ______
                                 
                 Questions Submitted by Hon. Todd Young
         re-evaluating business strategies in foreign countries
    Question. Since taking office, President Trump has made reducing 
drug prices one of his highest priorities--and has repeatedly spoken 
about his frustration with the U.S. subsidizing the costs of 
pharmaceuticals for the rest of the world. He has gone so far as to 
issue proposals, like the International Pricing Index (IPI) Model, in 
an attempt to bring down prescription drug prices.

    With the increased scrutiny of the industry and of the drug supply 
chain as a whole in the United States, have any of your companies re-
evaluated your business strategy in foreign countries?

    Answer. Please see answer below.

    Question. If not, then why?

    Answer. Please see answer below.

    Question. If a proposal, like IPI, were implemented, would it force 
your companies to potentially ``walk away from the negotiating table 
when other countries demand low prices subsidized by America's 
seniors,'' as HHS Senior Advisor for Drug Pricing Reform John O'Brien 
has said?

    Answer. Please see answer below.

    Question. What are some of your ideas on how we can ensure 
Americans aren't shouldering the full cost of pharmaceuticals?

    Answer. BMS reviews its business strategies within and outside of 
the U.S. on a regular basis. BMS believes that all patients deserve 
access to life changing medicines. Because of these ethical 
considerations, BMS would not walk away from discussions about access 
to our medicines in foreign countries. We believe that the most likely 
outcome of IPI is further delays in access to life extending and 
innovative medicines within the referenced countries, resulting in, for 
example, lower cancer survival rates.

    The IPI proposal imposes price controls in the U.S. based on the 
policies of foreign countries with socialized health-care systems that 
often deny their citizens access to innovative medicines. Patients in 
many of the countries included in the reference basket wait 
significantly longer for new, life extending and innovative medicines 
to reach them. Outside of the U.S., reimbursement of new medicines can 
often take more than 2 years. In Greece, for example, only 8 percent of 
new cancer therapies are available, and on average it requires 32 
months for these products to be available to patients. In comparison, 
in the U.S., 96 percent of new cancer drugs are available within 3 
months of market approval. Eventually, the industry often accepts 
foreign prices which do not recognize the value and cost-effectiveness 
of our medicines because patients can wait no longer.

    BMS is committed to working with Congress and the administration to 
advance better, more effective ways to lower drug prices for patients. 
As an alternative to the IPI model, finalizing the proposed rebate rule 
would lower seniors' out-of-pocket costs at the pharmacy counter. 
Regulatory reforms at the FDA are leading to more medicine approvals 
and greater competition in the market. Value-based arrangements (VBAs) 
and indication-based pricing (IBP) can reduce the payer risk of 
exposure to failed outcomes, more closely associate drug costs and 
value, and make prescription medicines more affordable for patients.
              foreign countries' pricing and reimbursement
    Question. President Trump and Secretary Azar have both repeatedly 
described their frustrations with ``foreign freeloading'' of U.S. drugs 
in the last year.

    ``When foreign governments extort unreasonably low prices from U.S. 
drug makers, Americans have to pay more to subsidize the enormous cost 
of research and development. . . . It's unfair and it's ridiculous, and 
it's not going to happen any longer.''

    Do you agree that because of foreign countries' pricing and 
reimbursement systems, U.S. patients and innovators are shouldering the 
burden for financing medical advances?

    Answer. Please see answer below.

    Question. How do foreign countries' pricing and reimbursement 
systems affect our prescription drug costs?

    Answer. Please see answer below.

    Question. Are foreign governments taking note of the concerns being 
raised by the Trump administration, and have they responded in any way?

    Answer. Please see answer below.

    Question. Has there been any noticeable change in any of our trade 
agreements since these concerns have been raised by the Trump 
administration?

    Answer. Drug pricing in markets outside of the U.S. must take into 
account significant differences in economic status, cultural beliefs 
and values, as well as differences in the local processes for setting 
prices, which vary significantly from market-to-market. Countries vary 
significantly in their per capita gross domestic product (GDP), their 
willingness to invest in, and provide rapid access to, health-care 
innovation, their focus on a single best average treatment for a 
population versus focusing on patient heterogeneity and preserving 
consumer choice and provider autonomy, and their tolerance and 
acceptability for optimal patient care.

    The countries selected for international comparison through the IPI 
model are not economically comparable with the U.S. Many of the 
countries in the IPI model, most notably Greece, the Czech Republic, 
and Italy, do not have comparable economies as measured in per capita 
gross domestic product (GDP). The significant difference in drug costs 
between the U.S. and other countries referred to by CMS in the IPI 
proposal is also seen with the comparative cost of physician services, 
hospital care, diagnostics, and medical devices. For example, according 
to a recent report by the OECD, hospital services in the U.S. cost 150 
percent more than in Japan, France, Germany, Finland and Spain; 170 
percent higher than in UK, Greece, and Italy.

    Through the USMCA and other trade actions, the Trump administration 
has taken steps to crack down on foreign violations of U.S. 
intellectual property rights. There remain, however, several practices 
that undermine U.S. intellectual property and violate existing trade 
deals. We need to continue to negotiate better trade deals with better 
enforcement that protect American medical innovations.
                  medicaid closed formulary proposals
    Question. In an attempt to bring down drug costs, various States 
have been exploring whether to exclude certain drugs from its Medicaid 
program. For example, the State of Massachusetts' recently asked CMS 
for permission to create a closed formulary where the State Medicaid 
program would pick at least one drug per therapeutic class. CMS denied 
their waiver request citing violation of Federal law, but this proposal 
does bring up important questions on how to contain drug prices in 
State Medicaid programs.

    If the principles of the Medicare Part D program--including the 
necessary patient protections--were applied to State Medicaid programs, 
do you think it lower drugs costs while ensuring access to patients?

    Answer. It is unlikely that applying Part D principles to Medicaid 
would lower drug costs. Medicaid is already a lower-cost channel and 
patients have little to no copay obligations.
                        medicaid ``best price''
    Question. In the Trump administration's Blueprint, they suggested 
that because drug manufactures have to give Medicaid the ``best price'' 
on drugs, there is no incentive to offer deeper discounts to other 
payers--both government and commercial--than what is already offered 
under the Medicaid Drug Rebate Program.

    Does the Medicaid ``best price'' requirement encourage 
manufacturers to increase initial prices?

    Answer. For BMS, Medicaid ``best price'' is not a consideration in 
determining initial product pricing.

    Question. What, if any, changes would you suggest we make to the 
program?

    Answer. As clarification, prices offered to Medicare Part D plans 
are excluded from Medicaid ``best price,'' and therefore, manufacturers 
can offer deeper discounts to Part D without impacting Medicaid best 
price.

    More generally, BMS recommends the creation of an exemption from 
best price and AMP for select value based purchasing arrangements and 
greater clarity on best price and AMP reporting on issues related to 
such arrangements.
                        outcomes-based contracts
    Question. In almost all of your testimonies, you highlight your 
support of outcomes-based contracts and how we need to be shifting our 
system toward that approach.

    How will these contracts lower drug costs for patients in both the 
near term and long-term?

    Answer. The goal and design of outcome-based contracts will vary 
depending on the specific drug and the therapeutic area/disease State 
which is being evaluated. In general, outcome-based contracts are 
designed to demonstrate the efficacy, safety, clinical superiority, 
cost savings and/or improvement in overall patient health outcomes. To 
the extent that outcomes-based contracts demonstrate improvement in 
clinical outcomes and/or reduction in overall health-care costs and 
facilitate access to appropriate medicines, patients will benefit from 
improved outcomes and reduced out-of-pocket costs, and Federal health-
care programs will benefit from lower overall health-care costs.

    Question. How will they lower overall health-care costs for our 
Federal programs?

    Answer. Please see answer to previous question.

    Question. What have the preliminary results looked like so far?

    Answer. Eliquis has demonstrated a better safety profile than 
alternate therapies (less bleeding events) as proven through outcomes-
based contracts using real world data. Oncology patients have higher 
rates of diagnostic testing done to monitor disease progression (as 
recommended by guidelines), through our testing based value-based 
contract.
                       transparency/point of sale
    Question. In almost all of your testimonies, you express your 
support for the Trump administration's proposal to allow manufacturers 
to provide PBMs up-front discounts that are passed onto patients at the 
point-of-sale.

    Do you feel like this proposal will make the transactions within 
the drug supply chain more transparent?

    Answer. To the extent that discounts provided by manufacturers to 
PBMs and payers are passed through to the patients at the point-of-
sale, transactions within the drug supply chain will be more 
transparent.

    Question. If so, would this transparency bring down drug costs--
overall and for specialty drugs?

    Answer. In terms of bringing down drug costs, the result of passing 
discounts through to patients at the point-of-sale will likely vary 
depending on the individual drug. We anticipate that patients who are 
prescribed high-cost, highly discounted drugs, primarily specialty 
drugs, and are subject to high co-insurance costs, will experience the 
greatest reduction in drug costs.
         the relationship between wholesalers and manufacturers
    Question. When talking about the pharmaceutical supply chain, a lot 
of focus has been placed on the Pharmacy Benefit Manager. But there's 
another side of the equation that I'd like to ask about.

    How do wholesalers negotiate pricing with manufacturers?

    Answer. Wholesalers and manufacturers negotiate distribution 
service agreements that include terms and fees. The fees are typically 
a percentage of list price.

    Question. What impact does this have on drug costs?

    Answer. It is BMS's understanding that the fees negotiated by 
wholesalers and manufacturers do not have a material impact on drug 
costs.

    Question. What incentives or disincentives do they have to contain 
price increases?

    Answer. This question is best answered by wholesalers.

                                 ______
                                 
                 Questions Submitted by Hon. Ron Wyden
                          proposed rebate rule
    Question. As has been done in many other settings, drug 
manufacturers said during the hearing that one reason list prices for 
drugs are high is that pharmaceutical benefit managers (PBMs) demand 
larger and larger rebates in order for the drug to receive favorable 
placement on a formulary. You and your colleagues who testified during 
the hearing stated if the administration's proposal on changes to the 
anti-kickback safe harbor for pharmaceutical rebates took effect, your 
company would likely lower list price.

    Like many Oregonians, I am skeptical drug manufacturers would 
voluntarily lower their prices. Therefore, would you support 
legislation that would (1) make similar changes the administration has 
put forward related to Part D and Medicaid managed care, (2) change the 
rebate system in a similar way to the proposal for the commercial 
market, and (3) require drug makers to lower the list price of their 
drugs equal to the amount of rebates provided today?

    Answer. BMS supports the extension of rebate reforms to the 
commercial market. However, given the significant market change in the 
proposed Part D safe harbor change, we urge the committee to pursue an 
implementation timeline that will allow manufacturers, PBMs, plans, 
retail pharmacies, wholesalers, and other impacted parties to address 
the many operational challenges for the industry. We anticipate that 
the implementation of the safe harbor change in Part D will provide 
important learnings, but in order to extend these changes to the 
commercial market, industry will need additional lead time to do so.

    Given the many payers and channels in the health-care market, an 
individual drug has multiple net price points. Moreover, the goals of 
the proposed rebate rule can be achieved not only through lower list 
prices, but also through negotiated discounts at the point-of-sale, or 
through some combination of the two approaches. We believe the goals of 
the proposed rule can be best achieved by giving manufacturers the full 
range of options in their negotiations with plans and PBMs. 
Consequently, BMS would not support legislation that required drug 
makers to lower the list price of their drugs equal to the amount of 
rebates provided today.

    There may be instances where a reduction in product list price is 
warranted, but with or without a list price change, in order for 
patients to benefit fully from the changes, regulations would need to 
ensure that manufacturer discounts are passed through to patients at 
the point-of-sale and that patient out-of-pocket costs are based on 
product net price.
                      medicaid drug rebate program
    Question. The Medicaid Drug Rebate Program (MDRP) requires 
manufacturers to provide a basic rebate and an additional inflationary 
rebate for both brand and generic drugs. The inflationary rebate is an 
increasingly substantial part of total rebates due in large part to 
large increases in drug prices that exceed inflation. Under current 
law, this inflationary rebate is capped at 100 percent of Average 
Manufacturer Price (AMP). This is the case even when manufacturers 
continue to raise their prices well above inflation.

    Please provide a list of all of your pharmaceutical products that 
have reached the Medicaid AMP rebate cap in any of the 20 quarters from 
January 1, 2014 through December 31, 2018.

    Answer. Please see answer below.

    Question. For each drug listed in response to question 1, please 
also provide a list of which quarters and years each drug hit the cap.


                                 Answer
------------------------------------------------------------------------
           Product                              Quarter
------------------------------------------------------------------------
BARACLUDE TAB 0.5MG            Q3 2014, Q4 2014, Q1 2015, Q2 2015, Q3
                                2015, Q4 2015
------------------------------------------------------------------------
BARACLUDE TAB 1MG              Q3 2014, Q4 2014, Q1 2015, Q2 2015, Q3
                                2015, Q4 2015
------------------------------------------------------------------------
COUMADIN TAB 4MG               Q1 2014, Q2 2014, Q3 2014, Q4 2014, Q1
                                2015, Q2 2015, Q3 2015, Q4 2015, Q1
                                2016, Q2 2016, Q3 2016, Q4 2016, Q1
                                2017, Q2 2017, Q3 2017, Q4 2017, Q1
                                2018, Q2 2018, Q3 2018, Q4 2018
------------------------------------------------------------------------
COUMADIN TAB 4MG (1BTLX1000)   Q3 2014, Q4 2014, Q1 2015, Q2 2015
 US
------------------------------------------------------------------------
COUMADIN TAB 1MG               Q1 2014, Q2 2014, Q3 2014, Q4 2014, Q1
                                2015, Q2 2015, Q3 2015, Q4 2015, Q1
                                2016, Q2 2016, Q3 2016, Q4 2016, Q1
                                2017, Q2 2017, Q3 2017, Q4 2017, Q1
                                2018, Q2 2018, Q3 2018, Q4 2018
------------------------------------------------------------------------
COUMADIN TAB 2MG               Q1 2014, Q2 2014, Q3 2014, Q4 2014, Q1
                                2015, Q2 2015, Q3 2015, Q4 2015, Q1
                                2016, Q2 2016, Q3 2016, Q4 2016, Q1
                                2017, Q2 2017, Q3 2017, Q4 2017, Q1
                                2018, Q2 2018, Q3 2018, Q4 2018
------------------------------------------------------------------------
COUMADIN TAB 5MG               Q1 2014, Q2 2014, Q3 2014, Q4 2014, Q1
                                2015, Q2 2015, Q3 2015, Q4 2015, Q1
                                2016, Q2 2016, Q3 2016, Q4 2016, Q1
                                2017, Q2 2017, Q3 2017, Q4 2017, Q1
                                2018, Q2 2018, Q3 2018, Q4 2018
------------------------------------------------------------------------
COUMADIN TAB 7.5MG             Q1 2014, Q2 2014, Q3 2014, Q4 2014, Q1
                                2015, Q2 2015, Q3 2015, Q4 2015, Q1
                                2016, Q2 2016, Q3 2016, Q4 2016, Q1
                                2017, Q2 2017, Q3 2017, Q4 2017, Q1
                                2018, Q2 2018, Q3 2018, Q4 2018
------------------------------------------------------------------------
COUMADIN TAB 10MG              Q1 2014, Q2 2014, Q3 2014, Q4 2014, Q1
                                2015, Q2 2015, Q3 2015, Q4 2015, Q1
                                2016, Q2 2016, Q3 2016, Q4 2016, Q1
                                2017, Q2 2017, Q3 2017, Q4 2017, Q1
                                2018, Q2 2018, Q3 2018, Q4 2018
------------------------------------------------------------------------
COUMADIN TAB 2.5MG             Q1 2014, Q2 2014, Q3 2014, Q4 2014, Q1
                                2015, Q2 2015, Q3 2015, Q4 2015, Q1
                                2016, Q2 2016, Q3 2016, Q4 2016, Q1
                                2017, Q2 2017, Q3 2017, Q4 2017, Q1
                                2018, Q2 2018, Q3 2018, Q4 2018
------------------------------------------------------------------------
COUMADIN TAB 3MG               Q1 2014, Q2 2014, Q3 2014, Q4 2014, Q1
                                2015, Q2 2015, Q3 2015, Q4 2015, Q1
                                2016, Q2 2016, Q3 2016, Q4 2016, Q1
                                2017, Q2 2017, Q3 2017, Q4 2017, Q1
                                2018, Q2 2018, Q3 2018, Q4 2018
------------------------------------------------------------------------
COUMADIN TAB 6MG               Q1 2014, Q2 2014, Q3 2014, Q4 2014, Q1
                                2015, Q2 2015, Q3 2015, Q4 2015, Q1
                                2016, Q2 2016, Q3 2016, Q4 2016, Q1
                                2017, Q2 2017, Q3 2017, Q4 2017, Q1
                                2018, Q2 2018, Q3 2018, Q4 2018
------------------------------------------------------------------------
COUMADIN TAB 6MG US            Q1 2014, Q2 2014, Q3 2014, Q4 2014, Q1
                                2015
------------------------------------------------------------------------
AVAPRO TAB 75MG                Q1 2014, Q2 2014, Q3 2014, Q4 2014, Q1
                                2015, Q2 2015, Q3 2015
------------------------------------------------------------------------
AVAPRO TAB 150MG               Q1 2014, Q2 2014, Q3 2014, Q4 2014, Q1
                                2015, Q2 2015, Q3 2015, Q4 2015, Q1 2016
------------------------------------------------------------------------
AVAPRO TAB 300MG               Q1 2014, Q2 2014, Q3 2014, Q4 2014, Q1
                                2015, Q2 2015, Q3 2015, Q4 2015, Q1 2016
------------------------------------------------------------------------
AVALIDE TAB 150/12.5MG         Q1 2014, Q2 2014, Q3 2014, Q4 2014
------------------------------------------------------------------------
AVALIDE TAB 300/12.5MG         Q1 2014, Q2 2014
------------------------------------------------------------------------

                medicaid drug rebate program compliance
    Question. I am concerned about recent reports and legal settlements 
surrounding drug manufacturers' failure to comply fully with the 
requirements of the MDRP. For example, an analysis by the U.S. 
Department of Health and Human Services Office of Inspector General 
found that between 2012 and 2016 taxpayers may have overpaid by as much 
as $1.3 billion for 10 potentially misclassified drugs. That is why I 
introduced the Right Rebate Act with Chairman Grassley to prevent drug 
manufacturers from manipulating Medicaid to increase their profits. 
However, I continued to be concerned about oversight and manufacturer 
compliance with the requirements of the Medicaid Drug Rebate Program. 
Accordingly, please describe the following:

    Your company's current compliance plan and procedures used to 
ensure compliance with the requirements of the Medicaid Drug Rebate 
Program including internal audits or other checks you use to identify 
compliance vulnerabilities.

    Answer. The Company routinely assigns new employees working in the 
government pricing area formal training on U.S. government pricing and 
contracting. This training includes an overview of the Medicaid Program 
obligations and requirements. BMS also maintains policy and procedural 
documents which govern compliance relative to the Medicaid Drug Rebate 
Program. In addition, BMS periodically holds informal training sessions 
as part of departmental and other internal meetings, where compliance 
training is provided on topics relevant to the Medicaid Drug Rebate 
Program. BMS has also identified key controls related to the Medicaid 
Drug Rebate Program which are independently tested as part of the 
Company's Sarbanes-Oxley controls. As part of these controls, all 
Medicaid pricing submissions are reviewed and approved by the 
appropriate Company management. In addition, BMS Global Internal Audit 
and Assurance periodically conducts internal audits of the Company's 
operations, which include activities that support the Medicaid Drug 
Rebate Program.

    Question. Any past or ongoing issues of non-compliance.

    Answer. There are no ongoing issues of non-compliance with the 
Medicaid Drug Rebate Program, nor were there any within the past 5 
years. (BMS interprets the question as asking for a reasonable period 
in the past, and has selected 5 years).

    Question. Any corrective actions taken to address identified 
problems or issues of non-compliance with the MDRP and how such steps 
were communicated to the Centers for Medicare and Medicaid Services.

    Answer. There are no ongoing issues of non-compliance with the 
Medicaid Drug Rebate Program, nor were there any within the past 5 
years. (BMS interprets the question as asking for a reasonable period 
in the past, and has selected 5 years).

    Question. Any steps taken to improve compliance and ensure that all 
Medicaid drug rebates owed to the Federal Government and the States are 
paid in full.

    Answer. In addition to the compliance and audit activities already 
outlined, the BMS Government Pricing team conducts regular cross-
functional information sharing meetings in order to facilitate 
communication within the organization, to gather all relevant pricing 
and contracting information, and to provide education that is focused 
on ensuring compliance with our Medicaid reporting obligations. The 
Government Pricing team also conducts quarterly Medicaid Best Price 
review meetings with key members of the pricing and contracting 
organization and requires that leaders of key functions within the 
pricing and contracting organization sign-off on quarterly Medicaid 
Best Price information prior to the Company's final. Additionally, the 
Company has made significant investments in the systems which are used 
to support the calculation and payment of Medicaid rebates to help 
ensure greater compliance, standardization and automation of our 
processes. BMS also maintains a Compliance and Ethics hotline and 
encourages all employees to raise potential compliance concerns so that 
they can be investigated and addressed.

    More specifically with regard to the payment of Medicaid drug 
rebates, based on the current portfolio of active drugs, all BMS drugs 
are classified as Innovator Single Source or Innovator Multiple Source 
drugs which are subject to the higher basic rebate calculation. When 
BMS launches a new drug that is subject to Medicaid reporting, the drug 
classification is reviewed as part of the Medicaid submission approval 
process.

    To the extent that BMS has questions on MDRP compliance or on 
interpretative approaches to MDRP price reporting, we communicate with 
the Centers for Medicare and Medicaid Services.
                 bonus payments tied to specific drugs
    Question. I am concerned by the potential for employee financial 
incentives to encourage high launch prices and price increases for 
prescription drugs.

    Is your salary, bonus, or other compensation tied to sales or 
revenue targets of a single product your company sells? Has it ever 
been? If yes, please state the product or products to which your 
salary, bonus or other compensation was tied.

    Answer. No, Dr. Caforio's salary and bonus are not tied to sales or 
revenue targets for a single product. Dr. Caforio's compensation is 
tied in part to the revenue of the Company as a whole. Please see 
answer below.

    Question. Is your salary, bonus, or other compensation tied to 
either revenue or net income of the company as a whole? Has it ever 
been? If yes, please explain what assumptions about price increases are 
used when the compensation committee sets revenue or net income goals. 
Does the compensation committee provide any guidance to executives in 
regards to the amount of revenue that the company will generate from 
price increases versus volume growth?

    Answer. Dr. Caforio's compensation is tied in part to the revenue 
of the Company as a whole. The revenue metric is based on the overall 
Company target for the applicable performance period (annual for annual 
bonus and longer-term, 3 years for Performance Share Units), which 
typically includes assumptions concerning both price changes and volume 
growth. Over the last few years, BMS' revenue growth has been primarily 
attributable to increased volume arising from increased demand for our 
products rather than price increases.

    Dr. Caforio's compensation is reviewed and recommended by the 
Compensation and Management Development Committee, which is a committee 
consisting of only independent directors, and approved by at least 
three-fourths of the independent directors of our Board of Directors. 
The Compensation Management and Development committee annually 
completes a thoughtful and rigorous evaluation of the Company's 
executive compensation program to ensure that the program is aligned 
with our mission and delivers shareholder value, while not encouraging 
excessive or inappropriate risk-taking by our executives. When 
determining metrics and setting incentive plan targets each year and 
for 3 year performance period, the committee is aware of the risks 
associated with drug pricing, among other risks, and ensures our plans 
do not incentivize risky behavior in order to meet targets and goals.
                               net prices
    Question. In your testimony you stated, ``for this reason, the 
average net pricing across our U.S. portfolio of medicines increased by 
5 percent of the last year-over-year for the last 5 years. Importantly, 
it did not increase at all in 2018 and we expect that it will not 
increase in 2019.'' Please describe how the company's year-over-year 
aggregate net price is calculated. Please also specifically address the 
following questions.

    Answer. Dr. Caforio testified that BMS's average net pricing across 
the company's U.S. portfolio increased by 5 percent or less year-over-
year for the last 5 years. Please see the answer below for a 
description of how year-over-year net price is calculated.

    Question. How many products are included in the calculation of the 
average net price change? What was the median net price change?

    Answer. Approximately 20 products are included in the calculation 
of the average net price change. The median net price change over the 
last 5 years is 3.4% based on the following net price change per year:


 
     2018           2017           2016           2015          2014
 
(0.3%)         1.6%           5.2%           3.4%           4.0%
 


    Question. Is net price weighted? If so, how? For example, in 
determining the aggregate net price does the company assign different 
weights to different products based on volume or other factors? Are 
``on patent'' and ``off patent'' drugs weighted identically? Are other 
statistical weights used or are all products treated equally?

    Answer. Net price is weighted according to the product's sales 
relative to total BMS sales. Year-over-year change in Net Price = 
Change in List Price + Change in effective discount rate across all 
channels. Patent and off-patent drugs are treated equally in the 
calculation.

    Question. Does the figure that you provided during your testimony 
account for U.S. prices, international prices, or both? Generally 
speaking, when your company reports net price changes, does it 
differentiate between U.S. and international prices?

    Answer. The figure included in Dr. Caforio's testimony accounted 
for U.S. prices. Yes, BMS discloses by region (i.e., U.S., Europe, Rest 
of World) in our quarterly 10Q and Annual 10K filings. However, the 
only net price changes specifically outlined (i.e., in percentage 
terms) is for the U.S.

    Question. Please list the five drugs your company sold in the U.S. 
that had the greatest year-over-year net price increase in 2018, noting 
the increase for each drug by dollar figure and percentage. Please list 
the five drugs your company sold in the U.S. that had the lowest year-
over-year net price increase (and/or the greatest decrease) in 2018, 
noting the increase (or decrease) for each drug by dollar figure and 
percentage.

    Answer. This question calls for information that BMS does not 
disclose publicly and considers to be competitively sensitive.

    Question. For 2018, what was the average net price change in the 
U.S. market for (1) drugs with no competition, (2) drugs with only 
branded competition, and (3) drugs with generic competition?

    Answer. This questions calls for information that BMS does not 
disclose publicly and considers to be competitively sensitive.

    Question. You stated that average net price increased 5 percent in 
2017, but did not increase in 2018, and that you do not expect it to 
increase in 2019. What factors contributed to the change from 2017 to 
2018? What would the net price increase have been if your company 
excluded the impact of drugs like Reyataz and Sustiva, which lost 
exclusivity in the United States at the end of 2017, and Daklinza, 
which the company reported losing revenue on?

    Answer. Dr. Caforio testified that BMS's average net pricing across 
the Company's U.S. portfolio increased by 5 percent or less year-over-
year for the last 5 years. Average U.S. net price remained unchanged 
from 2017 to 2018 (i.e., 0 percent net price increase from 2017 to 
2018), because discounts across all channels increased at a rate higher 
than list price increased. If drugs which lost exclusivity, like 
Reyataz, Sustiva and Daklinza, were excluded, the net price change 
would still be 0 percent.

                                 ______
                                 
              Questions Submitted by Hon. Robert Menendez
    Question. When new products enter the market, do drug companies set 
high initial rebates and then provide deep rebates in order to gain 
access to insurance plan's formularies?

    Answer. BMS does not. We cannot comment on the pricing practices of 
other manufacturers.

    Question. If CMS finalizes the rebate rule, do you anticipate 
future products entering the market with significantly lower initial 
list prices?

    Answer. If CMS were to finalize the rebate rule, the impact on list 
prices of future products would likely differ by product depending on 
such factors as the clinical profile of the product, competition, 
market dynamics, and the channel into which the product is primarily 
sold. As noted above, the goals of the proposed rule could be achieved 
through lower list prices, negotiated discounts at the point-of-sale, 
or some combination of these two approaches.

                                 ______
                                 
              Questions Submitted by Hon. Thomas R. Carper
    Question. What are your recommendations for lowering prices for the 
40 percent of drugs that do not offer rebates in Medicare Part D?

    Answer. BMS believes that market-based reforms are the best way to 
lower costs and maintain the appropriate incentives for innovation. BMS 
supports policies that enable payers to negotiate innovative and 
flexible ways to pay for medicines, including value-based purchasing 
arrangements. Additionally, we need to ensure generics are available 
whenever permissible under our system. BMS notes also that even 
manufacturers pay coverage gap discounts for all Part D drugs 
regardless of whether a payer rebate is provided for that drug.

    Question. In the health insurance plans that you offer your 
employees, do you ask your insurers to pass through the full 
manufacturer rebates to the beneficiaries?

    Answer. Based on the contract negotiated with the PBM with which 
BMS has contracted, BMS has elected to reinvest the rebates we would 
otherwise have received from the PBM to reduce the per claim cost for 
brand drugs across the entire population of members we cover. BMS 
provides health care coverage to approximately 10,000 active employees, 
4,000 retirees and 18,000 spouses and other dependents.

    Under this reinvested model, those rebate dollars are applied to 
reduce the negotiated rate our enrollees pay for brand drugs. This 
means that the PBM charges the plan a lower negotiated rate for all 
branded drugs (not just those associated with specific rebates), 
benefiting a broader portion of our covered population. Since our 
health plan benefit design uses a coinsurance for member cost sharing, 
this lower negotiated drug cost enabled by the application of the 
rebate value, reduces the coinsurance amount our members pay for their 
medications at the pharmacy counter.

    Question. The systems for pricing and distributing drugs are opaque 
and difficult to understand. What are your recommendations for 
increasing transparency in how your companies set the list prices for 
drugs, and for improving transparency in the supply chain for 
prescription drugs? Would you support Federal standards for 
transparency in setting the list prices for drugs?

    Answer. BMS intends to provide added transparency around the list 
prices for its medicines. We are creating pricing pages for all of our 
advertised medicine websites to include list price and additional 
information on out-of-pocket costs and support programs. Any DTC TV ads 
will direct patients to the site through a web link. Our plan is to 
have this information available by April 15, 2019. We solicited 
feedback from the patient community to ensure the resources we provide 
about pricing are meaningful to patients. The research suggests 
patients may misinterpret list price information in a television 
advertisement without additional context.

    BMS is complying with the recently enacted California drug price 
transparency legislation and would like to work with the committee on 
similar legislation at the Federal level, or legislation similar to the 
SPIKE Act (S. 474), both of which are intended to require manufacturers 
to disclose price increases above a certain threshold.

    Question. In nearly every sector of the health-care industry, 
Medicare, Medicaid, employers, and insurers are moving away from fee-
for-service payments to reimbursements based on value and performance. 
Prescription drugs and medical devices were the glaring exceptions to 
this trend until recently. How many of your drugs are included in 
value-based contracts and how many patients are benefiting from them? 
How do these value-based contracts work to lower drug prices for both 
patients and taxpayers?

    Answer. Currently, BMS has value-based contracts for two products. 
Approximately 39 million patients are eligible for potential coverage 
under those contracts.

    The goal and design of outcome-based contracts will vary depending 
on the specific drug and the therapeutic area/disease state which is 
being evaluated. In general, outcome-based contracts are designed to 
demonstrate the efficacy, safety, clinical superiority, cost savings 
and/or improvement in overall patient health outcomes. To the extent 
that outcomes-based contracts demonstrate improvement in clinical 
outcomes and/or reduction in overall health-care costs, patients will 
benefit from improved outcomes and reduced costs, and the Federal 
programs will benefit from lower overall health-care costs.

    Question. Last year, Senator Portman and I did an investigation on 
the pricing of an opioid overdose reversal drug called EVZIO, 
manufactured by Kaleo. Kaleo increased the price of EVZIO from $575 in 
2014 to $4,100 in 2017. We found that the best price Medicare was able 
to get for EVZIO, about $4,000, was much higher than the price other 
Federal programs and private insurers were able to get. It seemed that 
Kaleo was able to get this higher price of $4,000 from Medicare by 
helping doctors fill out paperwork showing that the drug was medically 
necessary, even though there are cheaper alternatives on the market. As 
a result of the investigation, Kaleo announced it will bring a generic 
version of the drug to market at only $168 per pack. Are any of your 
companies providing medical necessity paperwork to doctors in order to 
get your drugs covered by Medicare?

    Answer. BMS offers patient support programs that help eligible 
patients who are prescribed our medicines obtain access to those 
medicines. This includes assisting patients in navigating the insurance 
approval process. Consistent with longstanding OIG guidance and common 
industry practices, BMS does provide the template forms required by 
insurers for use in making coverage determinations, but BMS does not 
provide medical necessity content. That content must be independently 
provided by the prescribing health-care provider.

    Question. In 2017, the Rand Corporation estimated that biosimilar 
drugs, which are competitors to complex, biologic drugs, could save the 
United States more than $50 billion over the next decade. Some of you 
have also argued that increasing the use of biosimilar drugs would help 
lower drugs costs for consumers and taxpayers. What is delaying the 
uptake of biosimilar drugs in the United States? What policies do you 
recommend to increase the development of biosimilar drugs?

    Answer. BMS does not have a biosimilar or a branded product with 
biosimilar competition, and consequently, is not in a position to offer 
first-hand insight.

                                 ______
                                 
             Questions Submitted by Hon. Benjamin L. Cardin
    Question. The United States is one of the only countries in the 
world to allow prescription drug manufacturers to advertise directly to 
consumers through magazines, billboards, radio, and television 
commercials. While I will not argue that it is beneficial to educate 
consumers about an unfamiliar disease and encourage them to seek 
medical help, most commercials from all of your companies recommend 
asking about a specific brand name drug, not a medical condition. 
Furthermore, even if your advertisements follow all FDA rules and list 
medication side effects, they also almost always list these while a 
smiling, apparently healthy person is walking on a beach.

    Researchers say that this type of imagery, combined with viewing 
hours of drug commercials each month, leads consumers to underestimate 
the risks associated with medications. For the past decade, studies 
have shown that aggressive direct-to-consumer advertising is associated 
with rising drug prices and an increase in inappropriate drug 
prescriptions.

    Question. Since researchers have concluded that consumers are 
misunderstanding the benefits and risks described in your ads, what 
further policies could help you and your colleagues ensure that you are 
educating patients in a clear manner?

    Answer. BMS engages in DTC TV advertising selectively and only when 
we think it will help educate patients. Our DTC TV advertising is 
submitted to the FDA for advisory comments prior to being broadcast in 
accordance with FDA guidance. BMS believes that our DTC advertising 
clearly and appropriately communicates the benefits and risks of our 
medicines.

    BMS believes responsible DTC communications play a critical role in 
educating patients and families about treatment options and encourages 
them to have an informed discussion with their physician about the best 
treatment for their needs. BMS would be open to considering any 
additional policy proposals that further facilitate the achievement of 
this goal.
           pharmaceutical companies continue to raise prices
    Question. As you are well aware, high prescription drug prices are 
the number one concern for Americans and their families. According to 
the Organization for Economic Cooperation and Development, the average 
American spends around $1,208 annually on prescription drugs. There 
have been several instances where brand name or even generic drugs that 
have been on the market for years continue to increase in price.

    One of the most well-known examples is Mylan's increase of the 
price of EpiPen from less than $100 in 2007 to more than $600 in 2016. 
Another example, is the ever-increasing price of insulin. Sanofi 
increased the price of a vial of Lantus from $88.20 in 2007 to $307.20 
in 2017. And those are just a small sample of price increases.

    Why don't we see price decreases for drugs that have been on the 
market for years without new formulations or added benefit?

    Answer. Although list prices for a drug without new formulations or 
added benefits may not decrease over time, in our experience, net 
prices generally decrease over time and/or volume decreases 
significantly as generics enter the market.
                             pay for delay
    Question. Pay for delay is a tactic that more and more branded drug 
manufacturers have been using to stifle competition from lower-cost 
generic manufacturers. This allows you to sidestep competition by 
offering patent settlements that pay generic companies not to bring 
lower-cost alternatives to market.

    These ``pay-for-delay'' patent settlements benefit both brand-name 
pharmaceutical companies by helping them avoid costly patent litigation 
and general manufacturers by rewarding them a hefty sum to delay 
entering the market with a cheaper drug alternative. However, these 
deals do not benefit consumers. According to an FTC study, these 
anticompetitive deals cost consumers and taxpayers $3.5 billion in 
higher drug costs every year.

    Does your company partake in pay-for-delay settlements?

    Answer. No.

    Question. Why would a pharmaceutical company enter into a pay-for 
delay agreement?

    Answer. As stated above, BMS does not enter into any pay-for-delay 
settlements. We cannot comment on the actions and motivations of other 
manufacturers.

    Question. Do you think these agreements stifle competition and 
prevent generic alternatives to your branded medications?

    Answer. BMS agrees that patent settlement agreements that have 
substantial payments going from innovators to generics, and are solely 
intended to delay competition, are anticompetitive. In contrast, 
agreements that do not contain such substantial payments and properly 
balance litigation considerations often lead to earlier generic entry 
than patent expiration.
                            drug rebate rule
    Question. In January, the Department of Health and Human Services' 
(HHS) Office of Inspector General (OIG) promulgated a new regulation to 
remove regulatory safe harbor protections under the Anti-Kickback 
Statute (AKS) for rebates on prescription drugs rebates paid by 
manufactures to PBMs under Medicare Part D and for Medicaid managed 
care organizations (MCOs). The OIG proposal attempts to ban most 
rebates by eliminating their regulatory protections.

    The rule is predicted to increase net drug costs in its early 
years. The CMS actuaries estimate it would cost $196 billion over 10 
years. Despite this high price tag, the beneficiary benefits are 
limited. The proposed rule notes that under the CMS Actuary's analysis, 
the majority of beneficiaries would see an increase in their total out-
of-pocket payments and premium costs; reductions in total cost sharing 
will exceed total premium increases.

    I wanted to ask a question about the administration's rebate rule, 
which I understand that many of the drug manufacturers, and your main 
trade association, strongly support. According to an analysis of the 
rule by the Office of Actuaries at CMS, drug manufacturers are likely 
to initially retain 15 percent of the current rebates as higher net 
drug prices.

    Given that estimate, can you provide the committee with any 
assurances that prices will not increase under this proposed rule?

    Answer. BMS supports HHS's proposed rule because BMS believes it 
will lower patient costs at the point-of-sale and ensure patients 
realize the benefit of manufacturer discounts. We do not anticipate 
that manufacturer average net prices will increase as a result of this 
rule.

                                 ______
                                 
               Questions Submitted by Hon. Sherrod Brown
    Question. According to an article recently published in the Journal 
of the American Medical Association, medical marketers spent nearly $30 
billion dollars in 2016, up from $17 billion in 1997. Direct-to-
Consumer (DTC) advertising had the biggest percentage increase: from 
$2.1 billion, or 11.9 percent of all medical marketing, in 1997 to $9.6 
billion, or 32 percent of total spending, in 2016.

    Can you please provide what your ratio of spending on sales and 
marketing to research and development is today?

    Answer. BMS does not disclose sales and marketing investments 
separately. In 2018, BMS marketing, selling and administrative expenses 
were $4.6 billion, which is inclusive of sales and marketing, and R&D 
expenses were $6.3 billion. That ratio is approximately 7 to 10.
                             price-gouging
    Question. Sanofi, as I understand it, has made a pledge to the 
public to limit its price increases to the national health expenditures 
growth projection.

    Would your company commit to a cap on annual price increases as 
part of your PhRMA membership criteria?

    Answer. It is BMS's understanding that a cap on annual price 
increases as part of PhRMA membership would raise significant antitrust 
concerns.

    Question. What policies would you propose to help ensure lower 
launch prices for new drugs?

    Answer. BMS does not believe that government policies should govern 
launch pricing of new drugs. Payers, providers, patients, and the 
marketplace should freely assess the value of new innovative therapies 
relative to their improvement in outcomes and impact to total cost of 
care. At BMS, we believe the prices of our medicines reflect the value 
they bring to patients, healthcare providers, payers, and society as a 
whole.
                              transparency
    Question. In many of your testimonies, you mentioned that the 
current system of pharmacy benefit manager (PBM) back-end rebates do 
not rarely results in a scenario where the PBM passes on savings to 
consumers at the point of sale (POS). The administration recently 
proposed a rule to eliminate the anti-kickback statute safe harbor 
protections for these drug rebates.

    Do you agree that greater transparency should be required to 
understand how manufacturers and PBMs are negotiating prices and 
rebates to ensure that savings are passed down to beneficiaries?

    Answer. Yes, BMS agrees that manufacturer's net prices should be 
transparent to and passed through to beneficiaries. BMS also believes 
that this transparency should be required for all entities in the 
health-care market.
                                  pbms
    Question. An Axios article from March 7, 2019 highlights the fact 
that, while ``pharmaceutical companies put a lot of the blame for high 
drug prices on pharmacy benefit managers,'' many large pharmaceutical 
companies ``rely on PBMs to manage their own health care benefits.''

    In your role as an employer, does your company contract with a 
pharmaceutical benefit manager (PBM) to administer the prescription 
drug benefits for your employees and negotiate lower drug costs on your 
behalf?

    Answer. Yes.

    Question. For those of you who do use a PBM to help manage the 
prescription drug benefit for your employees, how do you utilize the 
rebates your PBM negotiates to lower health care costs or drug costs 
for your employee plans and what does your company do with that 
savings? Specifically, do the savings go toward lowing premiums?

    Answer. BMS uses a PBM for our self-funded Pharmacy Benefit 
Program, which is part of our overall healthcare plan. The PBM offers 
the option of direct point-of-sale rebates, however, based on the 
contract negotiated with the PBM, BMS has elected to reinvest the 
rebates we would otherwise have received from the PBM to reduce the per 
claim cost for brand drugs. Under this reinvested model those rebate 
dollars are applied to reduce the negotiated rate our enrollees pay for 
branded drugs. This means that the PBM charges the plan a lower 
negotiated rate for all branded drugs (not just those associated with 
specific rebates). Since our health plan benefit design uses a 
coinsurance for beneficiary cost sharing, this lower negotiated drug 
cost enabled by the application of the rebate value, reduces the 
coinsurance amount our members pay for their medications at the 
pharmacy counter. Under this model, a greater number of participants 
benefit from the value of the rebates.

    Question. For those of you who do use a PBM to help manage the 
prescription drug benefit for your employees, does your PBM offer 
point-of-sale rebates to your employees?

    Answer. Please see answer to previous question.

                                 ______
                                 
             Questions Submitted by Hon. Sheldon Whitehouse
    Question. Please describe any policy changes you support that would 
result in your company lowering the list prices of its drugs.

    Answer. BMS supports the HHS proposed rule to eliminate safe harbor 
protection for back-end rebates in Medicare Part D, and we believe it 
would lead to lower out-of-pocket costs. The goals of the proposed rule 
could be achieved through lower list prices, negotiated discounts at 
the point-of-sale, or some combination of these two approaches. While 
it is unclear how Part D plans and PBMs will react to the proposed 
rule, at this time, BMS envisions that we would offer point-of-sale 
discounts to Part D plans equivalent to the contracted rebate amount 
and will continue to assess the possibility of lowering list price on a 
product-by-product basis. Our ability to lower list prices, however, is 
constrained by the fact that the HHS proposed rule does not apply to 
the commercial insurance market, where we anticipate back-end rebates 
to continue for the foreseeable future.

    Question. How much does your company's research and development 
portfolio rely on taxpayer-funded research conducted by the National 
Institutes of Health (NIH)? How many of your company's products are 
based, at least in part, on NIH research, and how many are the result 
of research funded solely by your company?

    Answer. Government institutions such as NIH and NCI do critically 
important basic research. However, the most significant investment 
behind any molecule is the clinical development program, which is 
usually when a pharmaceutical company comes into the development 
process. On average it takes 10 to 15 years and about $2.5 B to bring a 
medicine to patients, depending on the asset, therapeutic area, number 
of indications, and other factors. This is highly dependent on the 
stage of the molecule/asset when it comes to BMS. There is also 
considerable risk of failure given the complexity of clinical 
development. Only about 12 percent of drugs that make it to Phase 1 
clinical trials result in an approved product.

    Question. In each of the last 5 years, how much has your company 
spent on research and development versus the advertising and marketing 
of your products?

    Answer. BMS does not publicly disclose specific advertising and 
marketing expenditures. The figures below are for marketing, sales and 
administrative expenses, which includes advertising and marketing 
expenditures.

        2018 spend:
        Marketing, selling, and administrative expenses: $4.6 billion
        Research and development expenses: $6.3 billion

        2017 spend:
        Marketing, selling, and administrative expenses: $4.8 billion
        Research and development expenses: $6.5 billion

        2016 spend:
        Marketing, selling, and administrative expenses: $5.0 billion
        Research and development expenses: $5.0 billion

        2015 spend:
        Marketing, selling, and administrative expenses: $4.8 billion
        Research and development expenses: $5.9 billion

        2014 spend:
        Marketing, selling, and administrative expenses: $4.8 billion
        Research and development expenses: $4.5 billion

    Question. During the hearing, you mentioned that your company would 
be likely to lower the list prices of its drugs if the recent proposal 
by the Trump administration to change the current system of rebates was 
extended to the private market.

    If the policy was extended to the private market, how large would 
the list price reductions be relative to the size of the rebates your 
company is currently providing?

    Answer. While it is unclear how health plans and PBMs would react 
if the HHS proposed rule's policy were extended to the private market, 
at this time, BMS envisions that we generally would offer point-of-sale 
discounts to health plans equivalent on average to the contracted 
rebate amount and would continue to assess the possibility of lowering 
list price on a product-by-product basis. In the absence of list price 
reductions, the policy requirement that manufacturer discounts be 
passed on at the point-of-sale would accomplish the goal of reducing 
patient out-of-pocket costs.

    Question. How will this proposal affect how your company sets the 
list prices for new drug products?

    If the proposal is finalized and not extended to the private 
market, will your company make any list price reductions? If so, how 
large would the reductions be relative to the size of the rebates your 
company is currently providing?

    Answer. While it is unclear how health plans and PBMs would react 
if the HHS proposed rule were finalized and not extended to the private 
market, at this time, BMS envisions that we would offer point-of-sale 
discounts to Part D plans equivalent on average to the contracted 
rebate amount and would continue to assess the possibility of lowering 
list price on a product-by-product basis. In the absence of a list 
price reduction, the proposed rule's requirement that manufacturer 
discounts be passed through to patients at the point-of-sale would 
accomplish the goal of reducing patient out-of-pocket costs.

                                 ______
                                 
                Question Submitted by Hon. Maggie Hassan
    Question. In June of 2018, the Medicaid and CHIP Payment and Access 
Commission (MACPAC) unanimously recommended under Recommendation 1.1 in 
their annual report to Congress that Congress remove the statutory 
requirement that manufacturers blend the average manufacturer price 
(AMP) of a brand drug and its authorized generic.\1\
---------------------------------------------------------------------------
    \1\ MACPAC, ``Improving Operations of the Medicaid Drug Rebate 
Program,'' https://www.macpac.gov/wp-content/uploads/2018/06/Improving-
Operations-of-the-Medicaid-Drug-Rebate-Program.pdf.

    This requirement created an unintended loophole. Rather than use 
the price of the authorized generic, drug companies can sell its 
authorized generic to a corporate subsidiary at an artificially lower 
price, and use that lower price to bring down the AMP, which in turn 
---------------------------------------------------------------------------
lowers the rebate obligation.

    Does your company engage in this practice? Has your company ever 
engaged in this practice in the past?

    Answer. No. BMS does not have any authorized generics with its own 
corporate subsidiary.

                                 ______
                                 
           Questions Submitted by Hon. Catherine Cortez Masto
    Question. Dr. Caforio, your company has entered a merger agreement 
to acquire Celgene, which makes the cancer drug Remlivid. The price of 
Remlivid was hiked nearly 20 percent in 2017, 5 percent last year, and 
another 3.5 percent just last month.\2\ Remlivid was also high on a 
list of brands whose manufacturers have refused to provide generic 
companies with the samples they need to submit an FDA application. 
Celgene refused 13 such inquiries, despite FDA's assurance that they 
were safe to share.\3\, \4\ Today Remlivid stands as a 
$70,000 sole source drug with no competition.\5\ You mention increasing 
access to generics as a priority in your testimony. In a case were 
Remlivid falls under your purview, what specific actions will you take 
to promote generic competition of that drug?
---------------------------------------------------------------------------
    \2\ https://www.reuters.com/article/us-celgene-results/celgene-
profit-tops-expectations-will-limit-
future-price-hikes-idUSKBN1KG1IC.
    \3\ https://www.fda.gov/Drugs/DevelopmentApprovalProcess/
HowDrugsareDevelopedandApp
roved/ApprovalApplications/AbbreviatedNewDrugApplicationANDAGenerics/
ucm607738.htm
?utm_campaign=FDA%20publishes%20list%20of%20inquiries%20from%20generic%2
0drug%20
applicants%20about%20RLD%20access&utm_medium=email&utm_source=Eloqua.
    \4\ https://www.npr.org/sections/health-shots/2018/05/17/571986468/
how-a-drugmaker-gamed-the-system-to-keep-generic-competition-away.
    \5\ https://twitter.com/megtirrell/status/1016769284025016320.

    Answer. BMS believes it is important to ensure generics are made 
available whenever that is permissible under our system, and supports 
the administration's focus on increasing the approval of generics. As 
part of that system, it is important that generic companies perform the 
---------------------------------------------------------------------------
needed testing to ensure product quality and patient safety.

    Until the transaction closes, BMS and Celgene will continue to 
operate as separate companies. BMS thus does not know and cannot 
comment on Celgene's practices as they relate to generic manufacturers. 
Once the transaction closes, BMS' practices with regard to generic 
manufacturers, including the provision of samples, will govern the 
combined portfolio.

    Question. As a portion of your revenue, for what percentage of the 
drugs in your portfolio do you offer no rebates? Based on the drugs in 
your pipeline, do you foresee that portion growing? For those drugs is 
your list price equal to your net price?

    Answer. Although the level of rebates varies by product and 
channel, BMS pays rebates for all products in our portfolio.

    Question. Do you invest more in R&D than you generate in US sales 
revenue? Please include specific figures.

    Answer. BMS invested $6.3 billion in R&D in 2018, which includes 
the discovery and development of new medicines.

    U.S. sales for 2018 were $12.5 billion.

    Question. Do you invest more in R&D than you spend on marketing and 
administration? What company functions do you consider to be included 
in administration? Please include specific figures.

    Answer. BMS does not publicly disclose specific marketing and 
administration expenditures. The figures below are for marketing, sales 
and administrative expenses, which includes marketing and 
administration expenditures.

        2018 spend:
        Marketing, selling, and administrative expenses: $4.6 billion
        Research and development expenses: $6.3 billion

        2017 spend:
        Marketing, selling, and administrative expenses: $4.8 billion
        Research and development expenses: $6.5 billion

        2016 spend:
        Marketing, selling, and administrative expenses: $5.0 billion
        Research and development expenses: $5.0 billion

        2015 spend:
        Marketing, selling, and administrative expenses: $4.8 billion
        Research and development expenses: $5.9 billion

        2014 spend:
        Marketing, selling, and administrative expenses: $4.8 billion
        Research and development expenses: $4.5 billion

    Question. Do you invest more in R&D than you spend on marketing and 
sales? What company functions do you consider to be included in sales? 
Please include specific figures.

    Answer. BMS does not publicly disclose the functions included in 
sales nor specific marketing and sales expenditures. Please see the 
answer to the prior question for R&D and marketing, selling and 
administrative expenses.

    Question. Why do you advertise for the drugs you manufacture? What 
factors do you consider in choosing which drugs you advertise?

    Answer. BMS believes responsible DTC communications plays a 
critical role in educating patients and families about treatment 
options, and encourages them to have an informed discussion with their 
physician about the best treatment for their needs. As a company, BMS 
engages in DTC TV advertising selectively and only when we think it 
will help educate patients. Currently BMS is engaging in DTC TV 
advertising for one product (Eliquis).

                                 ______
                                 
        Prepared Statement of Kenneth C. Frazier, Chairman and 
            Chief Executive Officer, Merck and Company, Inc.
    Mr. Chairman, Senator Wyden, and members of the committee, thank 
you for the opportunity to appear today. Merck's mission is to save and 
improve lives around the world by bringing forward breakthrough 
medicines and vaccines, and ensuring they are available and affordable 
to patients who need them.

    Merck is a science-based company that exists to help solve the 
world's most vexing medical challenges. We have a long history of doing 
this, from the development of most of the common childhood vaccines, to 
bringing the first protease inhibitor to patients, turning AIDS from a 
death sentence to a chronic disease, to developing the first statin, 
which led to significant reductions in the negative health effects of 
high cholesterol. This legacy of invention continues today.

    Research is at the core of who we are and what we do. Last year, 
Merck invested nearly $10 billion in research and development toward 
our mission of preventing, treating, and curing disease, and since 2010 
we've invested nearly $70 billion in these efforts. Our more than 
12,000 researchers are focused on cancer, infectious diseases, and 
Alzheimer's, as well as other major health challenges that affect large 
numbers of people around the world. For our breakthrough immuno-
oncology drug Keytruda alone we have over 900 clinical trials under 
way.

    In pursuit of these efforts, we are also investing significantly in 
infrastructure here in the United States. We have invested more than $5 
billion in the last five years, and we plan to invest $9 billion more 
over the next few years to increase manufacturing capacity and open two 
new discovery research centers.

    Our mission is to go where the science leads us, which means we 
don't allocate resources only to addressing diseases in wealthy 
countries; we focus our efforts on conditions that significantly impact 
people living all over the world.

    For instance, we are proud to have deployed 70,000 doses of our 
experimental Ebola vaccine in the Democratic Republic of the Congo, 
working in partnership with the Centers for Disease Control and 
Prevention, the Biomedical Advanced Research and Development Authority, 
and the Department of Health and Human Services. For efforts such as 
this there is no commercial opportunity, but we pursue them because 
these are the challenges that Merck was created to tackle.

    At the end of the day we do all of this to serve patients. We 
understand that patients are having a harder and harder time affording 
their health care, including their prescription medicines. As a result 
of robust negotiation and competition in the marketplace, medicine 
costs are growing at the slowest rate in years, but the system is still 
not working for patients who are too often being asked to pay more out-
of-pocket due to the complex system of pricing, distribution, and 
insurance. I am here today to suggest a few ways that we can address 
this problem together.

    First, we want to be clear that our industry has a duty to be 
responsible in our pricing practices and contribute to solutions that 
address the affordability problems facing patients. We have all heard 
the egregious examples of irresponsible behavior. At Merck, we have a 
history of responsible pricing. To help increase transparency about our 
pricing practices, we publicly disclose information about our prices in 
the U.S. and the rebates and discounts we provide to payers--including 
insurers, pharmacy benefit managers, and the government. Last year, we 
pledged that we will not increase our average net prices for our 
portfolio by more than the rate of inflation annually.

    From 2010 to 2017, Merck's average net price increase across our 
portfolio each year has been in the low to mid-single digits. In fact, 
our average net price declined in 2017 by almost 2 percent. In 2017, 
the average discount for our medicines and vaccines was more than 45 
percent lower than the list price. Despite these very large discounts, 
patients do not see a commensurate benefit. In fact, patient out-of-
pocket costs continue to rise, and patients are being asked to shoulder 
more of their drug costs than other health-care services.

    Second, we must ensure that patients get the benefit of the large 
rebates and discounts that manufacturers are paying to PBMs and 
insurance companies.

    The incentives in the current system are badly misaligned. As a 
result, the current system of drug competition that depends on rebating 
is not working for patients. The growing gap between our list prices 
and our net prices that results from rebating has created incentives 
for supply chain entities to favor products with higher list prices. 
For instance, in 2016, we introduced our hepatitis C therapy, Zepatier, 
at a list price that was 42 percent below the price of the therapy that 
was the standard of care. However, due to the misaligned incentives in 
the supply chain that create a preference for higher priced products, 
we had difficulty gaining access for patients in certain market 
segments.

    This kind of misalignment can have a significant negative impact on 
patients because their cost-sharing is often based on the list price of 
a drug, even when insurance companies and PBMs are paying a fraction of 
that price. Our current system that incentivizes high list prices and 
large rebates as a mechanism to keep insurance premiums low means that 
sick patients are essentially subsidizing healthy patients. In this 
way, our insurance system is broken. We urge you to support action to 
make sure that all patients benefit from the discounts we make 
available.

    Third, we can significantly reduce spending on pharmaceuticals, 
especially for patients, by ensuring that we have a viable market for 
biosimilars in the United States. We believe, like with traditional 
small molecule medicines, generic competition after a reasonable period 
of exclusivity will create headroom for patients to afford the newest, 
most innovative medicines. Research shows that generics and biosimilars 
are expected to drive savings of $105 billion through 2022 in the 
U.S.\1\
---------------------------------------------------------------------------
    \1\ IQVIA Institute for Human Data Science. ``Medicine use and 
spending in the U.S.: A review of 2017 and outlook to 2022.'' https://
www.iqvia.com/institute/reports/medicine-use-and-spending-in-the-us-
review-of-2017-outlook-to-2022. Published April 19, 2018. Accessed 
April 2018.

    However, we share the concerns expressed by FDA Commissioner 
Gottlieb regarding the challenges biosimilars have experienced in 
penetrating the market. Merck introduced a biosimilar to the market 18 
months ago at a 35 percent discount to the originator product, yet we 
have captured only a tiny fraction of the market. In general, 
biosimilars competition thus far has resulted in moderation of prices, 
but actual utilization of the biosimilars remains modest at best. We 
fear that an environment where market entry of biosimilars brings value 
to the market, but little or none of that value accrues to the 
---------------------------------------------------------------------------
biosimilar, will not be sustainable.

    Therefore, we urge Congress to pursue policies to encourage and 
support biosimilar uptake and utilization in order to realize these 
potential savings for the system and patients. These could include 
reduced cost sharing in Medicare Part B.

    Fourth, we believe that prices can more align with a drug's value 
when manufacturers and payers are able to negotiate innovative 
contracts that base payment on a drug's benefits. Manufacturers should 
be rewarded based on the value that our therapies deliver. When we 
developed our breakthrough immuno-oncology treatment Keytruda, we 
incorporated a biomarker where clinically appropriate so that we could 
identify those patients most likely to benefit, but this is not always 
the case. We did this because we believe in giving the right medicine 
to the right patient at the right time. This is important both for 
therapeutic and economic reasons. If patients regularly take our 
medicines as they are prescribed, we are prepared to stand behind their 
effectiveness.

    Moving to a system where we are reimbursed for the value our 
medicines provide would be revolutionary. Yet there remain major 
regulatory and operational obstacles to value-based payment and 
contracting in the commercial and public markets, which we urge 
Congress to address.

    Fifth, we support efforts to encourage generic competition. A 
version of Chairman Grassley's CREATES Act could make some needed 
reforms to encourage generic competition, and there are likely other 
policies we should consider as well to ensure there is no inappropriate 
gaming of the system.

    We also support the idea of eliminating the use of drug company 
coupons in cases where a brand name drug now has generic competition. 
This slows the use of generics and violates the spirit of the Hatch-
Waxman drug price competition law.

    Finally, we would also like to work with the committee to find ways 
to end the price gouging pursued by those who jack up the prices of 
off-patent drugs that have no competition. These high prices hurt 
patients and do not create incentives for the kind of cutting edge 
research we pursue.

    These six changes could bring real relief to patients while 
preserving the incentives that allow us to invest billions in 
developing new medicines. These are exciting times, when decades of 
investment in scientific research are yielding life-changing 
discoveries. But it is the investment of today that fuels the 
innovations of tomorrow, and if we damage the ecosystem that drives 
those investments, we'll never know what we could have achieved for the 
patients we are all here to serve.

    The single most important contribution that we make at Merck--to 
economies, to health care, and to individual patients and their 
families--is to continue making the necessary costly and long-term 
investments in R&D and persuading thousands of brilliant researchers to 
sit at a lab bench and try to create something transformative--despite 
the overwhelming odds that their efforts will not succeed, since 9 out 
of 10 compounds that even start clinical trials will fail.

The solutions to health-care spending and out-of-pocket costs for 
patients must be achieved in a way that provides the balance necessary 
for innovation to occur. The innovation ecosystem includes academia, 
small biotechnology companies, large pharmaceutical companies, 
government, and patients and providers. It is incumbent on all of us to 
solve the affordability challenges of today's patients without 
compromising our ability to invent for tomorrow's patients.

    I'd like to end on a personal note. My mother died when I was a 
child and my siblings and I were raised by my dad who worked as a 
janitor in North Philadelphia. He was a giant in my life and it was 
devastating when Alzheimer's took him away from me and my family.

    Last year, after spending many years and over a billion dollars, 
Merck had to end development of a promising new Alzheimer's therapy 
because it simply didn't work. Yet we continue on, seeking better 
approaches. And I truly believe Merck or one of the other companies at 
this table can and will find a medicine that will ensure that no one 
will have to experience the pain of seeing a loved one taken from them 
in this way.

    But, our success depends on having a U.S. market that is free, 
competitive, and predictable. The changes I've discussed today have the 
potential to vastly improve that market and help patients survive and 
thrive without financial hardship. I am here to pledge our cooperation 
with you for creating such changes.

    Thank you.

                                 ______
                                 
        Questions Submitted for the Record to Kenneth C. Frazier
               Questions Submitted by Hon. Chuck Grassley
    Question. At the hearing, you testified that Merck does not 
withhold samples from generic manufacturers in order to block generic 
versions of your drug from entering the market. You also expressed your 
support for the ``Creating and Restoring Equal Access to Equivalent 
Samples Act,'' also known as the CREATES Act.

    However, the FDA has a list on its website which identifies 
reference listed drug (RLD) access inquiries where brand manufacturers 
may have prevented generic companies from obtaining samples of products 
necessary to support FDA approval. Cubist Pharmaceuticals is on this 
FDA list. According to news reports, Merck bought this company in 2014. 
If this is accurate, this would appear to contradict your testimony at 
the hearing that Merck has not withheld samples of their products to 
delay generic competition.

    Could you please explain in detail the discrepancy between your 
testimony and the FDA list?

    Has Merck ever blocked access to samples?

    Answer. Merck does not block generic companies from accessing 
samples. Your inquiry references FDA's website for reference listed 
drugs, or RLDs, which lists inquiries the agency has received from 
potential generic companies for samples of RLDs. Importantly, FDA's 
website also provides the following statement in describing the various 
inquiries related to the RLDs listed: ``We note that FDA has not 
independently investigated or confirmed the access limitations 
described in the inquiries received.''

    As FDA's website details, ENTEREG (alvimopan) has a restricted 
distribution requirement mandated by its FDA-approved Risk Evaluation 
and Mitigation Strategy (REMS). ENTEREG is the only Merck product 
subject to an FDA-approved REMS. Under this program, ENTEREG is 
available only to hospitals that perform surgeries that include a bowel 
resection and dispensed by pharmacies that are enrolled in the E.A.S.E. 
ENTEREG REMS Program. This program is designed to ensure that ENTEREG 
is used in accordance with the FDA-approved label.

    Merck acquired ENTEREG from Cubist Pharmaceuticals in 2015. Since 
acquiring ENTEREG, whenever Merck has received a request from a 
generics company to supply ENTEREG, we have directed them to the draft 
FDA Guidance which outlines how the generics company can obtain a 
letter from FDA stating that their study protocols contain the 
appropriate safety protections for products subject to this type of 
REMS. If provided with a copy of such a letter from FDA, Merck is happy 
to work with generics companies on supply arrangements. To date, we 
have not received any such letters. FDA's website also details that the 
agency has not issued any Safety Determination Letters for samples of 
ENTEREG.

    Question. The Department of Health and Human Services' proposed 
rule, ``Fraud and Abuse; Removal of Safe Harbor Protection for Rebates 
Involving Prescription Pharmaceuticals and Creation of New Safe Harbor 
Protection for Certain Point-of-Sale Reductions in Price on 
Prescription Pharmaceuticals and Certain Pharmacy Benefit Manager 
Service Fees,'' envisions that drug manufacturers will offer up-front 
discounts rather than the back-end rebates that are now commonly 
provided. Some observers argue that a 1996 court case called into 
question whether manufacturers could offer up-front discounts, 
resulting in today's rebate-based system. I've heard differing opinions 
as to whether the issues related to the initial court case are still 
relevant. If the HHS proposed rule is finalized, can you assure the 
committee that your company will offer up-front discounts? If not, why?

    Answer. Merck is aware that some in the industry have asked whether 
the antitrust laws as interpreted in the In re Brand Name Prescription 
Drugs Antitrust Litigation would limit the ability of manufacturers to 
offer point-of-sale discounts (as opposed to rebates). But, the U.S. 
antitrust laws, including the Robinson-Patman Act, apply to price 
discrimination in any context (including rebates), and nothing about In 
re Brand Name Prescription Drugs Antitrust Litigation changes this 
fact. As a result, Merck commits that, if the OIG's Proposed Rule is 
finalized, we will modify our contracts to comply with the new safe 
harbors and will provide discounts in a manner consistent with the new 
regulations.

    Question. Please describe how you expect your company to respond to 
the HHS proposed rule to eliminate safe harbor protection for back-end 
rebates in Medicare Part D that is referenced above if it is finalized. 
Assuming you are confident that antitrust laws do not prevent your 
company from offering up-front discounts, specifically, do you envision 
that your company lowers the list price of a drug to the current after-
rebate net price, offer discounts equal to the current rebate amount, 
or a combination of both?

    Answer. We expect that the robust negotiations that occur today 
will continue in the highly competitive Part D market, and we expect to 
realize the same level of net price that we do today. In fact, we 
expect that there could be additional pricing pressure under the new 
system, which could lead to lower net prices.

    Over time, we expect that our list prices will go down if the 
misaligned incentives across the system are addressed. We are currently 
working with other stakeholders in the system to solve the operational 
challenges that will enable these changes.

    But, it is also important to note that if the rule is implemented, 
Medicare beneficiaries' out-of-pocket costs will be reduced, 
independent of any lowering of list prices, since their cost-sharing 
will be based on the net price. Nonetheless, we believe the rebate rule 
will align incentives in a way that will restrain list prices.

    If this rule is implemented as written, it would only apply to our 
contracts with PBMs and health plans for Medicare Part D and Managed 
Medicaid. If PBMs and health plans maintain the rebate model in the 
commercial market, we would still have commercial contracts based on 
rebates, which would be subject to the existing constraints to lowering 
list price. We also would still need a mechanism to revalue drug in the 
distribution channel in a financially viable manner.

    Question. To what extent are the back-end rebates your company 
currently offers contingent on the amount of market share realized for 
your drugs as a result of Part D plan formulary placement and other 
techniques?

    Answer. Our contracts typically provide rebates to Part D plans in 
exchange for a specified formulary status. We are aware of only one 
current agreement that makes a Part D rebate contingent on reaching a 
certain market share.

    Question. Please provide a breakdown of percentage of sales that go 
to each payer (including Medicare, Medicaid, private pay, other) and a 
similar percentage by volume of the total number of each drug compared 
to total volume. Please provide this data for the most recent year 
available.

    Answer. The table below provides a proxy for volume by reporting 
percentages based on gross sales from 2018, given that there is no 
standard unit of volume measure that can be applied across our diverse 
product line (e.g., tablet products, injectable products, vaccines).

------------------------------------------------------------------------
                        Segment                            Gross/Volume
------------------------------------------------------------------------
CML+Specialty Pharm                                                  28%
------------------------------------------------------------------------
Hospital / GPO / 340B                                                23%
------------------------------------------------------------------------
Medicare Part D                                                      19%
------------------------------------------------------------------------
Medicare Part B                                                      12%
------------------------------------------------------------------------
Medicaid                                                             12%
------------------------------------------------------------------------
Federal                                                               6%
------------------------------------------------------------------------

        Notes: CML refers to private commercial payers; Medicare Part B 
        also encompasses Part B products sold through Medicare 
        Advantage Plans; Medicaid includes fee for service and managed 
        Medicaid; Federal includes the VA, DoD, Coast Guard, Public 
        Health Service and other similar purchasers.

    Question. Do your companies hire consultants or lobbyists to 
promote products at State Medicaid Pharmacy and Therapeutics 
Committees?

    Answer. No. While Merck does contract with lobbyists who may 
interact with individuals associated with State Medicaid programs, they 
do not promote products at State Pharmacy and Therapeutics Committees.

    Question. To whom do you disclose advocacy activities surrounding 
State Medicaid programs, if at all?

    Answer. Merck requires employees to adhere to State ethics law 
requirements for disclosing advocacy activity. Additionally, employees 
who attend Medicaid program meetings must comply with State public 
meeting law requirements pertaining to their attendance and 
participation.

    Question. Please describe how the costs of patient assistance 
programs are accounted for within your company's financial statements. 
Please also describe the types of market information, such as 
prescribing and use patterns, that your company collects from different 
types of patient assistance programs and patient hub services.

    Answer. For purposes of this question, we are interpreting 
``patient assistance programs'' to include the Merck Patient Assistance 
Program (Merck PAP), which provides free product to qualifying 
patients, Merck donations to independent patient assistance 
foundations, and Merck's patient coupon programs which help eligible 
privately insured patients afford their prescribed medications. Merck 
also makes available patient hub support programs to assist patients 
with accessing their prescribed medications.

    With respect to the company's financial statements, for Merck PAP 
and Merck's donations to independent patient assistance foundations, 
the costs are recorded to the ``Selling, general and administrative'' 
category on our Consolidated Statement of Income. The co-pay assistance 
made available to patients through Merck's coupon programs is treated 
as a reduction to Merck's gross sales for the applicable products and 
is included in the ``Sales'' line of our Consolidated Statement of 
Income. The expenses associated with administering Merck's coupon 
programs are recorded in the ``Selling, general and administrative'' 
category on our Consolidated Statement of Income. Similarly, the 
expenses associated with administering Merck's patient hub support 
programs are recorded in the ``Selling, general and administrative'' 
category of our Consolidated Statement of Income.

    Merck receives different types of market information in connection 
with the different programs identified above. For market information 
associated with the Merck PAP, the Merck PAP reviews data, such as 
patient insurance status and household income, to determine an 
individual's eligibility for PAP program enrollment. Merck PAP also 
tracks the number of prescriptions associated with the PAP for 
budgeting and planning purposes, but Merck PAP does not collect 
information associated with the courses of therapy for individual 
patients. With respect to Merck's donations to independent patient 
assistance foundations Merck does not receive any market information. 
Merck receives only a final report that confirms donations were 
received and spent in their totality for their intended purpose.

    With respect to Merck's patient coupon programs, Merck may receive 
certain market information to assist it with evaluating whether its 
coupons programs are functioning consistent with their intended purpose 
and whether the vendor is meeting its contractual obligations. The 
information also may be used to assist Merck with budgeting and 
planning. For example, Merck may receive information about: the product 
filled; the product dispensing date and site; the prescriber; the 
number of patients enrolled in the coupon program; the number of 
coupons redeemed; the patient out-of-pocket costs associated with the 
use of a Merck coupon; and the benefit amount Merck pays on behalf of 
privately-insured patients using a coupon.

    With respect to Merck's patient hub support programs, Merck may 
receive certain market information to assist it with evaluating whether 
its hub support programs are functioning consistent with their intended 
purpose and whether the vendor is meeting its contractual obligations. 
The information also may be used to assist Merck with budgeting and 
planning. For example, Merck may receive aggregate information about: 
call type, frequency, and vendor response times; the number of patients 
enrolled in the program; patient enrollment demographic and diagnosis 
information; patient benefit investigations; insurance coverage 
information for the applicable product; and pharmacy product 
fulfillment information.

    Merck's third-party contractors may receive additional, patient-
specific information that is not shared directly with Merck.

    Question. Please provide a list of all contributions since January 
1, 2014, that your company has made to any tax-exempt organizations 
working on issues related to drugs within your product lines, including 
but not limited to patient groups, disease awareness groups, medical or 
professional societies, universities or hospitals, industry 
associations or leagues. For each contribution, please provide the name 
of the organization that received the donation, the date the donation 
was made, the amount of the donation, and a description of the purpose 
of the contribution (i.e., was the contribution for the general fund, a 
specific purpose to a specific program, or continuing medical 
education). Please also note whether the contribution was unrestricted 
or restricted; if it was restricted, please explain all restrictions. 
Finally, if your company maintains a foundation or other separate 
charitable arm, please provide the name of all such entities, and list 
all donations made from that entity or entities.

    Answer. The information concerning our Philanthropic grants and 
charitable contributions, including contributions made through the 
Office of Corporate Responsibility, our company's Foundation, U.S. 
Global Human Health, and the MSD for Mothers Program can be found here: 
https://www.msdresponsibility.com/ethics-transparency/transparency-
disclosures/. Please note the website does not include grants or 
contributions from Merck's Research Laboratories or Merck's 
Manufacturing Division.

    In addition, the information concerning our grants of more than 
$500 provided by the company's Global Human Health division to U.S. 
organizations in support of independent, accredited educational 
programs for health-care professionals, as well as grants to patient 
organizations and other medical education or scientific societies and 
organizations in the United States, Europe, the Middle East, Africa and 
Canada can also be found at the website referenced above.

    Question. Pay for delay agreements cost consumers and taxpayers 
billions in higher drug costs every year. The FTC has gone after drug 
companies that enter into these settlements where the brand pays the 
generic company to keep its lower cost alternative off the market. I'm 
the lead Republican sponsor of S. 64, the Preserve Access to Affordable 
Generics and Biosimilars Act, which would help put an end to these 
deals.

    Do you agree that these pay-off agreements keep drug costs high for 
patients because they delay competition?

    Answer. Patent settlement agreements challenged by the FTC as anti-
competitive, in which brands pay generic companies to stay out of the 
market when it would otherwise be lawful for them to enter the market, 
could delay patient access to lower cost alternatives. In contrast, 
patent settlement agreements in which the brand, while not conceding 
the invalidity or non-infringement of the patents, but in the face of 
the uncertainties and costs associated with protracted litigation, 
settles cases in a manner that allows a generic to enter the market 
prior to expiry of the brand's patents could actually accelerate 
patient access to lower cost alternatives. Still, brands do not enter 
into such agreements lightly because they believe in the rights of 
patent holders to vigorously enforce their intellectual property rights 
in court. At the end of the day, these settlements do not delay entry 
or cause the loss of any lawful competition because entry prior to the 
expiry of these patents would be unlawful infringement unless and until 
the generic manufacturers prevailed in court.

    Question. Has your company ever entered into these kinds of 
settlements with a generic company?

    Answer. Merck has not entered into patent settlement agreements 
with generic companies to delay their entry past when it would 
otherwise be lawful for them to enter the market. Merck has been party 
to a number of patent settlement agreements that provide for generic 
market entry prior to patent expiry, including some that have provided 
some level of exclusivity for a limited time. These agreements allowed 
generic products to enter the market earlier than would have otherwise 
been the case. The FTC has not challenged as anti-competitive any of 
these types of agreements involving Merck.

    Question. Do you support the pay for delay bill?

    Answer. Merck does not support S. 64 in its present form. Merck 
believes that the development of the law through the judicial process 
is the most effective way to address the balance between antitrust law 
and patent law raised by settlement agreements. S. 64 upsets the 
careful balance embodied in a rule-of-reason analysis by creating a 
presumption that ``anything of value'' or an ``exclusive license'' are 
anticompetitive, thus denying an antitrust defendant the ability to 
present and rely on countervailing evidence of pro-competitive effects, 
such as the impact on competition by the entry of the generic product 
before the expiration of the patent or statutory exclusivity term. As 
noted by the Supreme Court in FTC v. Actavis:

        Given these factors, it would be incongruous to determine 
        antitrust legality by measuring the settlement's 
        anticompetitive effects solely against patent law policy, 
        rather than by measuring them against procompetitive antitrust 
        policies as well.\1\
---------------------------------------------------------------------------
    \1\ FTC v. Actavis, 570 U.S. 136, 148 (2013).

    S. 64 also seeks to insulate the FTC's fact finding from judicial 
review. Finally, the retroactive application of the provisions of the 
bill to June 2013 is unworkable. While there had been a split between 
the Circuit Courts over the proper analysis of reverse payment 
settlements, the Supreme Court's opinion in Actavis in 2013 settled 
that split by holding that patent settlements including those with 
reverse payments were subject to a rule-of-reason analysis. That 
decision did not provide hard and fast rules for the balance between 
antitrust and patent principles. To impose a process that alters that 
balance, and to do so retroactively, is imprudent and unfair.
                           rebate traps/walls
    Question. I'm increasingly concerned about the effect of so-called 
``rebate traps'' or ``rebate walls'' on patients' access to quality, 
lower cost medicine. I understand there is ongoing litigation 
challenging these practices as anti-competitive.

    Does your company engage in the bundling of rebates over multiple 
products? If so, why? And what benefit does the consumer gain from 
that?

    Answer. Merck understands this question to refer to certain 
concerns about contracting practices applied to contracts between 
manufacturers and PBMs or health plans. Merck offers rebates to payers 
on bundles of products within certain product families (e.g., JANUVIA 
and JANUMET, ASMANEX TWISTHALER and ASMANEX HFA). These bundled 
discounts benefit patients by ensuring that multiple therapies are 
maintained on a PBM or health plan formulary, thus ensuring wider 
patient access to our medicines at lower costs to the payer. Merck also 
offers discounts with respect to multiple bundled products outside of 
the PBM and health plan contracts, such as in the vaccine and hospital 
markets.

    Question. Does your company view these practices as anticompetitive 
or harmful to patients' access to quality, lower cost medicine?

    Answer. No. Merck believes the rebates it offers to payers on 
pharmaceutical products are procompetitive. Merck does not believe that 
its rebating practices are harmful to patients.

    Question. If a policy were adopted to eliminate rebates, or to 
require that rebate savings be passed on to the consumer, would that in 
and of itself solve the issue of rebate ``traps'' and ``walls''? And 
would consumers benefit from such a policy?

    Answer. Merck is very supportive of current efforts to change the 
system. We believe these efforts will remove misaligned incentives 
within the system, drive more transparency in the system and, most 
importantly, benefit patients by lowering out-of-pocket costs. It is 
difficult to predict whether these changes will solve all of the issues 
seen today, but Merck is committed to working toward additional 
solutions if issues remain after these changes are implemented.
                              drug pricing
    Question. When setting the list price of a drug, does your company 
consider regulatory costs or compliance? If so, how specifically do 
those factors affect the list price of a drug? Please provide at least 
one specific example, if applicable, from your current product 
portfolio.

    When setting the list price of a drug, does your company consider 
the risk of liability or litigation? If so, how specifically do those 
factors affect the list price of a drug? Please provide at least one 
specific example, if applicable, from your current product portfolio.

    Answer. In setting the list price for a drug, we do not 
specifically consider the regulatory costs or compliance or the risk of 
liability or litigation.

    Merck approaches pricing from the perspective of value. This 
approach looks at the value that a medicine provides through multiple 
lenses with the goal of reflecting its benefit to patients and to 
society, while at the same time paying an appropriate return on 
invested capital to our investors, to ensure that we are able to 
sustain R&D. While each individual situation varies based on factual 
circumstances and market dynamics, generally, we consider:

          Value provided to patients--to what extent does a new 
        medicine or vaccine establish a new standard of care that has 
        the potential to significantly extend and improve patient 
        lives?

          Value provided to health-care systems--to what extent does a 
        new medicine or vaccine reduce the costs associated with 
        hospitalization and other costly complications of disease if 
        not appropriately (or optimally) treated?

          Unmet need--does a new medicine or vaccine address a 
        critically unmet medical need, where few or no treatments 
        exist?

          Access--what is the ability of various customers around the 
        world--including national, regional or local institutional 
        payers, physicians, employers and patients--to pay for our 
        products?

          R&D sustainability--given the long-term risk and cost of 
        capital, can we appropriately compensate our investors to 
        ensure continued investment in the kind of risky and capital-
        intensive research and development that will bring forward 
        medically important breakthroughs?

          Competition--what are the costs of other treatments 
        currently on the market relative to the value provided by 
        Merck's products?

                                 ______
                                 
                Questions Submitted by Hon. Pat Roberts
    Question. What role do you see value-based arrangements (VBAs) 
playing in the effort to reduce prescription drug costs? What potential 
do these arrangements have to find the ``sweet spot'' between 
controlling costs to patients and encouraging innovation of new drugs?

    How can VBAs help lower what patients pay out-of-pocket?

    Can Congress do more to allow for and encourage the use of VBAs?

    Answer. For more than 10 years, Merck has worked with payers and 
health-care providers to advance alternative pricing and contracting 
arrangements, and Merck has publicly shared information about value-
based agreements (VBAs) it entered into with the payers Aetna and 
Cigna. We are continuously reviewing ways in which the company may 
enter into VBAs for our products, which we define as a contractual 
framework aimed at achieving a mutually agreed upon value objective 
that that drives greater value from health care spending. Merck is 
interested, where business and customer objectives align, to implement 
VBAs across the health care market, including Medicare Part D, Managed 
Medicaid, and Fee-For-Service Medicaid.

    By aligning payments for medicines more directly with their value 
in improving meaningful health outcomes and/or reducing the need for 
other health-care services (such as hospitalizations), VBAs make 
pharmaceutical manufacturers accountable for the results their products 
achieve in a concrete way and can help improve patients' health and 
maximize the benefits of health-care spending. A recent Avalere survey 
of payers found that 44 percent of payers engaged in outcomes-based 
contracts experienced improvements in patient outcomes.\2\
---------------------------------------------------------------------------
    \2\ Avalere Health. ``Outcomes-Based Contracts: Payer 
Perspectives.'' Avalere Policy 360. July 19, 2018.

    VBAs also can increase patient access to new therapies which could 
ultimately improve patient outcomes. A payer that might otherwise 
decline to cover a new medicine (or that would only cover the medicine 
with significant utilization management restrictions or high cost 
sharing) due to uncertainties about the expected percentage of its 
patient population who would benefit might increase access to the 
medicine if the manufacturer shared the risks of the medicine's 
performance. These agreements may make medicines more accessible to 
patients who will benefit from them and increase competition in 
relevant therapeutic classes.\3\ Researchers have found that value-
based arrangements can improve patient access to medicines.\4\
---------------------------------------------------------------------------
    \3\ Staley, L. ``A Drug's Worth: Why Federal Law Makes It Hard to 
Pay for Pharmaceutical Performance.'' Boston University Law Review. 
2018;98(1):303-334. (``Tying reimbursement to health outcomes presents 
new opportunities for competition with rival manufacturers. . . . [A] 
manufacturer that can demonstrate sustained health benefits in post-
market studies may distinguish itself from competitors.'').
    \4\ See, for example, description of Entresto and Repatha contracts 
in: Seely, E., and Kesselheim, A. ``Outcomes-Based Pharmaceutical 
Contracts: An Answer to High U.S. Drug Spending?'' Commonwealth Fund. 
Issue Brief. September 2017.

    While Merck has had some experience with VBAs, these efforts have 
not been as robust as they could be due to the challenges involved in 
developing and implementing them. In addition to infrastructure and 
data limitations, challenges include regulatory limitations such as 
government pricing frameworks (e.g., Medicaid Best Price (BP) rules, 
---------------------------------------------------------------------------
Medicare's Average Sales Price (ASP)) and Federal fraud and abuse laws.

    Accordingly, we support opportunities that would enable greater 
experimentation in the design, structure, and implementation of VBAs. 
Further innovation in this space is needed to support overall sponsor 
and plan learning, and to determine the range of potential benefits to 
diverse health systems and beneficiaries. To fully achieve these goals, 
however, the impacts of the current regulatory framework, including 
government pricing requirements, the Federal Anti-Kickback Statute 
(AKS), and overall environmental barriers, must be analyzed and 
addressed as appropriate. Policy solutions such as the Patient 
Affordability Value and Efficiency Act (PAVE), introduced by Senators 
Warner and Cassidy, could provide necessary regulatory flexibility for 
properly structured VBAs.

                                 ______
                                 
              Questions Submitted by Hon. Michael B. Enzi
    Question. More than 10 years ago, I worked on a bipartisan basis 
with my good friends Ted Kennedy and Orrin Hatch to develop a 
biosimilars approval pathway. One of the difficult things was 
accounting for the differences between biosimilars and generics. I have 
said before that if a drug was a three-bedroom, two-bath home, a 
biologic would be a skyscraper. The size and complexity of the items 
are just that different. I understand that it is much harder to build a 
skyscraper without blueprints than a house. Even though the science has 
come a long way since then, there aren't as many biosimilars on the 
market as we might have hoped. Do you think the incentives in the law 
appropriately account for the differences between biosimilars and 
generics?

    Answer. In general, biosimilars competition thus far has resulted 
in moderation of prices, but actual utilization of the biosimilars 
remains modest at best. We fear that an environment where market entry 
of biosimilars brings value to the market, but little or none of that 
value accrues to the biosimilar patient or the health-care system, will 
not be sustainable.

    Merck remains an advocate for rigorous biosimilarity standards 
globally, and we believe that all biosimilar product applicants should 
be required to demonstrate equivalence (i.e., biosimilarity) in safety 
(including immunogenicity) and efficacy, and no differences in purity 
and potency profiles between the originator reference product and the 
biosimilar candidate. We believe the FDA has instituted such a standard 
with its Totality of the Evidence approach, ``including structural and 
functional characterization, nonclinical evaluation, human PK and PD 
data, clinical immunogenicity data, and comparative clinical study(ies) 
data.'' \5\
---------------------------------------------------------------------------
    \5\ U.S. Food and Drug Administration. ``Scientific Considerations 
in Demonstrating Biosimilarity to a Reference Product Guidance for 
Industry.'' (Apr. 2015), https://www.fda.gov/downloads/drugs/guidances/
ucm291128.pdf.

    We are urging Congress to pursue policies to encourage and support 
biosimilar uptake and utilization in order to realize these potential 
savings for the system and patients. These policies could include 
---------------------------------------------------------------------------
reduced cost sharing in Medicare Part B.

    Question. I know there are proposals to essentially pay more for 
biosimilars to make them more attractive, but that is not exactly what 
we were intending when we wrote the law. Can you talk about adverse 
incentives in the market and any barriers to market penetration that we 
might address to help improve patient access to these lower cost 
products?

    Answer. Merck introduced a biosimilar to the market 18 months ago 
at a 35-
percent discount to the originator product, yet we have captured only a 
tiny fraction of the market. Uptake of the product was limited, we 
believe due to physician confusion regarding interchangeability and 
extrapolation, and a lack of physician, patient, and payer incentives. 
While we believe that the prescribing physician must always have the 
authority to designate exactly which biological product is dispensed to 
the patient, we believe there are market barriers that hamper 
appropriate adoption of biosimilars. Merck encountered the following 
market barriers that hampered uptake of RENFLEXIS:

          We have observed cases where Medicare Advantage plans seem 
        to be imposing utilization management controls that require 
        providers to first use the reference biologic before providing 
        coverage for the biosimilar. This is a significant disincentive 
        to biosimilar uptake in that setting, and we believe is 
        contrary to policy objectives to promote the uptake of 
        biosimilars.

          Some providers may be hesitant to adopt biosimilar products 
        due to overall confusion and the current lack of standardized 
        definitions of biosimilarity (including the concepts of 
        extrapolation and interchangeability). Currently, we lack 
        standardized definitions of interchangeability as it relates to 
        clinical significance, and concerns about the clinical 
        appropriateness of switching stable patients to a biosimilar 
        product have been contentious issues for some prescribers. 
        Further, prescribers may be comfortable with a single switch 
        (i.e., moving a stable patient from a reference product 
        treatment protocol to a biosimilar), but may have concerns 
        about switching a patient multiple times, absent the 
        interchangeability designation. We believe that regulatory 
        clarification of these terms and concepts could help mitigate 
        concerns for providers and support biosimilar product adoption.

    We suggest the following policy changes to help encourage and 
support prescriber biosimilar utilization:

          Consider options to reduce or eliminate patient cost sharing 
        in Medicare Part B for biosimilars. While some Part B 
        beneficiaries are already able to reduce their 20 percent cost 
        sharing via supplemental coverage, we believe eliminating cost 
        sharing will encourage many physicians to use biosimilars for 
        their patients. A similar approach in Part D and in Medicaid 
        for small-molecule generics has driven generic utilization up 
        to 90 percent.\6\
---------------------------------------------------------------------------
    \6\ Department of Health and Human Services. Office of Inspector 
General. ``Generic Drug Utilization in the Medicare Part D Program.'' 
(Nov. 2007), https://oig.hhs.gov/oei/reports/oei-05-07-00130.pdf.

          Create pathways for MA and Part D plans to receive bonus 
        payments and/or enhanced star ratings for achieving metrics 
        related to access to biosimilars. This will incentivize plans 
        to implement policies that drive additional utilization of 
---------------------------------------------------------------------------
        biosimilars.

          Consider alternative reimbursement methodologies that adjust 
        the current Part B reimbursement formula. The current structure 
        in Part B to reimburse at ASP + 6 percent of the reference 
        product's ASP ensures there is no reimbursement downside to 
        physicians for using biosimilars. But so far, the evidence does 
        not suggest the current reimbursement rate sufficiently 
        incentivizes providers to use biosimilar products. Congress 
        should consider alternatives to further incentivize physician 
        adoption of biosimilars.

                                 ______
                                 
                Questions Submitted by Hon. John Cornyn
    Question. We continue to hear that rebates negotiated off of the 
list price of a drug are both good and bad.

    Pharmacy benefit managers and plans have argued that rebates are 
used to lower premiums across the board and that it is the best way to 
seek a price concession on otherwise expensive drugs.

    Your industry argues that these payers are insisting on higher 
rebates that can only be achieved by raising list prices.

    But patients often lose under this system, with out of pocket costs 
being tied to list price. Insulin patients appear to be routinely 
impacted by this perversity in the system.

    Please explain to the committee how your company would reduce list 
prices if rebates were no longer a part of the equation?

    What assurance can you provide that you would in fact lower your 
prices?

    What actions should be taken to ensure that patients are actually 
seeing the benefits of lower out of pocket costs?

    Answer. As we stated when we reduced the list price of several of 
our products in July 2018, we will continue to look for opportunities 
to reduce our list prices. We think the proposed rule will help create 
those opportunities, but it can't happen overnight. We are currently 
working with other stakeholders in the system to solve the operational 
challenges that will enable these changes.

    It is important to note that if the proposed rule is implemented, 
Medicare beneficiaries' out-of-pocket costs will be reduced, 
independent of any lowering of list prices, since their cost-sharing 
will be based on the net price. Further actions to ensure patients 
actually see the benefit of lower out of pocket costs might include 
prohibitions on changes in benefit design by payers/PBMs that could 
allow payers/PBMs to defeat the intent of delivering savings to 
patients.

    Question. If rebates are driving high list prices for drugs as drug 
manufacturers' claim, why do you think that Part B drugs, which have no 
PBM rebates, are also seeing significant price increases? Whose fault 
is that?

    Answer. While the misaligned incentives of Part D are partly 
responsible for PBMs favoring high list prices, that is not the sole 
dynamic associated with price increases. There may be unique reasons 
for price increases on specific products given their individual 
circumstances, including competitive dynamics and the costs of clinical 
research and manufacturing improvements. In addition, while PBMs 
generally do not manage Part B benefits, this does not mean that 
discounts are not provided or applied on these products. Providers and 
commercial health plans do receive discounts, the average of which is 
passed along to patients through ASP-based reimbursement.

    The 20-percent coinsurance paid by a patient is based on the ASP, 
which reflects the average discounts received by providers and payers.
                     biosimilar competition/insulin
    Question. Biosimilars have been much anticipated as a solution to 
the drug pricing crisis. In particular, the FDA is moving to make 
insulin a biologic that would be subject to biosimilar competition in 
the future.

    But we are hearing from all of you that the biosimilar market 
doesn't work and the benefit of these cheaper but equally effective 
alternatives are really not available to U.S. patients.

    Can a biosimilar version of insulin be part of the solution for 
diabetes patients?

    If so, what changes need to be made to the system so that patients 
and the taxpayer can realize the benefit of biosimilars? (Merck gave up 
on pursuing a biosimilar to Sanofi's Lantus \7\)
---------------------------------------------------------------------------
    \7\ Arlene Weintraub. ``Merck Ditches Biosimilar Lantus, But Will 
That Ease the Path for Mylan's Rival Insulin Product?'' FiercePharma. 
(Oct. 12, 2018), https://www.fiercepharma.com/pharma/merck-ditches-
biosimilar-lantus-but-will-ease-path-for-mylan-s-rival-insulin-product.

    Answer. We believe there is potential for significant savings to 
national health-care systems if high quality biosimilars--including 
insulins--can be brought to the market and compete with those biologics 
---------------------------------------------------------------------------
that have exhausted their intellectual property protections.

    Biosimilar products are still the subject of a great deal of 
confusion, particularly among providers, regarding the scientific, 
regulatory, and clinical basis for extrapolation and interchangeability 
decisions made by the FDA. Merck has urged the FDA to expand its work 
in educating providers and other stakeholders on these topics.

    Beyond that, we believe Congress should consider policy changes to 
help encourage and support prescriber biosimilar utilization. In our 
Blueprint comments to HHS we recommended incentives targeting patients, 
health plans, and providers that we believe can move the needle in 
stimulating uptake. One idea is for Congress to consider options to 
reduce or eliminate patient cost sharing in Medicare Part B for 
biosimilars.

    As to the Lantus biosimilar, after a comprehensive assessment of 
the current and future market environment for insulin glargine, 
including biosimilars, which included an assessment of anticipated 
pricing and cost of production, we made the business decision to 
terminate our agreement on the commercialization of the Lusduna pen and 
vial. There is already one other biosimilar glargine on the market and 
others on the way. So, we concluded this space was, or soon will be, 
adequately covered. This will allow us to allocate resources to other 
products in development.

                                 ______
                                 
                 Questions Submitted by Hon. Todd Young
         re-evaluating business strategies in foreign countries
    Question. Since taking office, President Trump has made reducing 
drug prices one of his highest priorities--and has repeatedly spoken 
about his frustration with the U.S. subsidizing the costs of 
pharmaceuticals for the rest of the world. He has gone so far as to 
issue proposals, like the International Pricing Index (IPI) Model, in 
an attempt to bring down prescription drug prices.

    With the increased scrutiny of the industry and of the drug supply 
chain as a whole in the United States, have any of your companies re-
evaluated your business strategy in foreign countries?

    If not, then why?

    If a proposal, like IPI, were implemented, would it force your 
companies to potentially ``walk away from the negotiating table when 
other countries demand low prices subsidized by America's seniors,'' as 
HHS Senior Advisor for Drug Pricing Reform John O'Brien has said?

    What are some of your ideas on how we can ensure Americans aren't 
shouldering the full cost of pharmaceuticals?

    Answer. Merck continually reevaluates its business strategies in 
all markets, seeking in particular to make its vaccines and medicines 
accessible to patients while realizing their full value in foreign 
markets with regulatory schemes that do not recognize the full value of 
these products and artificially reduce prices. Nevertheless, in most 
markets there are very limited options for adjusting prices to 
recognize the full value of our medicines and vaccines. One-sided and 
onerous pricing and reimbursement schemes most often leave little room 
for negotiation.

    With regard to ``walking away from the negotiating table,'' Merck 
always reserves that option. However, we recognize the serious and 
negative implications on patient health and access, the company's 
ultimate mission, and other possible repercussions that would result 
from denying patient access to our medicines. Moreover, foreign 
governments can resort to compulsory licensing, essentially seizing 
patent rights, where a company refuses to market a product, which also 
makes it difficult to withdraw from a foreign market.

    Regarding ideas to ensure Americans aren't shouldering the full 
cost of pharmaceuticals, we believe appropriate U.S. trade strategies 
are a promising avenue to dealing with unreasonable foreign government 
action. Positive actions in the U.S. can also reduce prices in the 
U.S., including removing misaligned incentives that cause PBMs to favor 
more expensive products and lead to higher out-of-pocket costs for U.S. 
patients, like the administration's proposal regarding the rebate safe 
harbor. One potential proposal would be to create a special USTR 
negotiator specifically for drug pricing issues.
              foreign countries' pricing and reimbursement
    Question. President Trump and Secretary Azar have both repeatedly 
described their frustrations with ``foreign freeloading'' of U.S. drugs 
in the last year.

    ``When foreign governments extort unreasonably low prices from U.S. 
drug makers, Americans have to pay more to subsidize the enormous cost 
of research and development. . . . It's unfair and it's ridiculous, and 
it's not going to happen any longer.''

    Do you agree that because of foreign countries' pricing and 
reimbursement systems, U.S. patients and innovators are shouldering the 
burden for financing medical advances?

    How do foreign countries' pricing and reimbursement systems affect 
our prescription drug costs?

    Are foreign governments taking note of the concerns being raised by 
the Trump administration and have they responded in any way?

    Has there been any noticeable change in any of our trade agreements 
since these concerns have been raised by the Trump administration?

    Answer. We agree that foreign countries' pricing and reimbursement 
systems result in their not paying enough to support the 
biopharmaceutical innovation from which they benefit. This causes the 
U.S. to shoulder more than its fair share of financing medical 
advances. These pricing and reimbursement systems do not necessarily, 
however, affect prescription drug costs in the U.S. in any direct or 
algorithmic fashion. Rather, Merck approaches pricing from the 
perspective of value. This approach looks at the value that a medicine 
provides through multiple lenses with the goal of reflecting its 
benefit to patients and to society, while at the same time paying an 
appropriate return on invested capital to our investors, to ensure that 
we are able to sustain R&D. While each individual situation varies 
based on factual circumstances and market dynamics, generally, we 
consider:

          Value provided to patients--to what extent does a new 
        medicine or vaccine establish a new standard of care that has 
        the potential to significantly extend and improve patient 
        lives?

          Value provided to health-care systems--to what extent does a 
        new medicine or vaccine reduce the costs associated with 
        hospitalization and other costly complications of disease if 
        not appropriately (or optimally) treated?

          Unmet need--does a new medicine or vaccine address a 
        critically unmet medical need, where few or no treatments 
        exist?

          Access--what is the ability of various customers around the 
        world--including national, regional or local institutional 
        payers, physicians, employers and patients--to pay for our 
        products?

          R&D sustainability--given the long-term risk and cost of 
        capital, can we appropriately compensate our investors to 
        ensure continued investment in the kind of risky and capital-
        intensive research and development that will bring forward 
        medically important breakthroughs?

          Competition--what are the costs of other treatments 
        currently on the market relative to the value provided by 
        Merck's products?

    Prices in other countries often reflect different value systems and 
criteria. It is important to note that all components of the health 
care system, including hospital services, physician services, physician 
salaries, and medical devices are considerably less expensive in 
foreign countries than in the U.S. That said, we agree that foreign 
countries' pricing and reimbursement systems result in their not 
sufficiently supporting biopharmaceutical innovation. While foreign 
governments are generally aware of concerns raised by the Trump 
administration, we are not aware of any substantive response.

    There has been some change in trade agreements, but more work needs 
to be done. U.S. free trade agreements address discriminatory 
approaches to pricing and reimbursement and ensure fair treatment for 
innovative medicines through commitments established by trade partners. 
Free trade agreements can help advance innovation, versus approaches 
proposed by the administration such as the International Pricing Index 
that have the potential to stifle investment in R&D by driving down 
prices across markets.

    Here are three examples:

          A 2004 U.S. Department of Commerce study examining OECD 
        countries found that foreign price controls restrict the 
        ability to innovate in our sector and identified trade 
        agreements as a key lever. We strongly encourage the Trump 
        administration to update this report to reflect the impact of 
        continued price controls in OECD countries.

          The pharmaceutical pricing and reimbursement provisions in 
        the U.S.-
        Mexico-Canada Agreement commit governments to provide 
        transparency and due process protections in national 
        pharmaceutical reimbursement processes and decisions. This is a 
        step in the right direction, but more is needed to ensure that 
        many countries, such as Canada, appropriately recognize the 
        value of innovative medicines.

          The Trump administration has worked to ensure adherence to 
        commitments in pricing and reimbursement in the Korea-U.S. Free 
        Trade Agreement, and direct advocacy by the U.S. has also made 
        an impact in Japan to mitigate some approaches.

    There is clearly more work to be done in these areas, and trade 
tools such as a new U.S.-Japan Free Trade Agreement, are critical.
                  medicaid closed formulary proposals
    Question. In an attempt to bring down drug costs, various States 
have been exploring whether to exclude certain drugs from its Medicaid 
program. For example, the State of Massachusetts' recently asked CMS 
for permission to create a closed formulary where the State Medicaid 
program would pick at least one drug per therapeutic class. CMS denied 
their waiver request citing violation of Federal law, but this proposal 
does bring up important questions on how to contain drug prices in 
State Medicaid programs.

    If the principles of the Medicare Part D program--including the 
necessary patient protections--were applied to State Medicaid programs, 
do you think it lower drugs costs while ensuring access to patients?

    Answer. There are important differences in the population covered 
under Medicaid and the coverage options available that need to be 
considered. Medicaid beneficiaries remain some of the sickest and most 
complex populations of patients, with sometimes inconsistent 
relationships with health-care providers and other complicating factors 
that make accessing medical care already difficult. Many Medicaid 
patients have complex diseases for which there are not always 
therapeutically equivalent drugs available, so access to the specific 
drug providers prescribe is crucial.

    Part D is a highly competitive, successful program that has come in 
at nearly half the cost that was originally projected. It also has 
extremely high rates of beneficiary satisfaction--generally around 90 
percent. While Part D offers multiple plan options and levels of 
benefits such that patients can shop for plans that cover their 
medicines at varying levels of cost-sharing, patients in Medicaid do 
not have access to alternative coverage options. So, if a medicine they 
need is not available, they do not have the ability to switch plans or 
otherwise obtain access to the medicine.

    As a result, the use of restrictive formularies is likely to result 
in adverse effects on beneficiary outcomes and increased costs when 
applied in Medicaid. While the patient protections that exist in Part D 
may provide beneficiaries with an option to appeal formulary decisions, 
it would be complicated to navigate for Medicaid patients and their 
providers, who may have limited resources to take on the additional 
responsibility and may take time that patients with complex conditions 
may not have.

    Medicaid is already receiving the best price based on the statutory 
rebate and States have flexibility to exert utilization management 
controls to negotiate supplemental rebates. Given this, we believe that 
applying the principles of Medicare Part D in Medicaid is not likely to 
result in lower drug costs without significantly impacting access.
                        medicaid ``best price''
    Question. In the Trump administration's Blueprint, they suggested 
that because drug manufactures have to give Medicaid the ``best price'' 
on drugs, there is no incentive to offer deeper discounts to other 
payers--both government and commercial--than what is already offered 
under the Medicaid Drug Rebate Program.

    Does the Medicaid ``best price'' requirement encourage 
manufacturers to increase initial prices?

    What, if any, changes would you suggest we make to the program?

    Answer. We can speak only to Merck's practices, and Merck does not 
consider the Medicaid Best Price requirement when setting initial 
prices. Merck approaches pricing from the perspective of value. This 
approach looks at the value that a medicine provides through multiple 
lenses with the goal of reflecting its benefit to patients and to 
society, while at the same time paying an appropriate return on 
invested capital to our investors, to ensure that we are able to 
sustain R&D. While each individual situation varies based on factual 
circumstances and market dynamics, generally, we consider:

          Value provided to patients--to what extent does a new 
        medicine or vaccine establish a new standard of care that has 
        the potential to significantly extend and improve patient 
        lives?

          Value provided to health-care systems--to what extent does a 
        new medicine or vaccine reduce the costs associated with 
        hospitalization and other costly complications of disease if 
        not appropriately (or optimally) treated?

          Unmet need--does a new medicine or vaccine address a 
        critically unmet medical need, where few or no treatments 
        exist?

          Access--what is the ability of various customers around the 
        world--including national, regional or local institutional 
        payers, physicians, employers and patients--to pay for our 
        products?

          R&D sustainability--given the long-term risk and cost of 
        capital, can we appropriately compensate our investors to 
        ensure continued investment in the kind of risky and capital-
        intensive research and development that will bring forward 
        medically-important breakthroughs?

          Competition--what are the costs of other treatments 
        currently on the market relative to the value provided by 
        Merck's products?

    We recognize the value that the Medicaid program provides for 
patients who need it, and we do not believe the ``best price'' 
requirement encourages manufacturers to increase initial prices.

    Merck believes that the exclusion of value-based arrangements 
(VBAs) from the calculations of Best Price, Average Manufacturer Price, 
and Average Sales Price would facilitate VBA implementation, which 
would further align prices with the value that pharmaceutical products 
bring to the market.
                        outcomes-based contracts
    Question. In almost all of your testimonies, you highlight your 
support of outcomes-based contracts and how we need to be shifting our 
system toward that approach.

    How will these contracts lower drug costs for patients in both the 
near term and long-term?

    How will they lower overall health-care costs for our Federal 
programs?

    What have the preliminary results looked like so far?

    Answer. For more than 10 years, Merck has worked with payers and 
health-care providers to advance alternative pricing and contracting 
arrangements and Merck has publicly shared information about value-
based agreements (VBAs) it entered into with the payers Aetna and 
Cigna. We are continuously reviewing ways in which the company may 
enter into VBAs for our products, which we define as a contractual 
framework aimed at achieving a mutually agreed upon value objective 
that that drives greater value from health-care spending. Merck is 
interested, where business and customer objectives align, to implement 
VBAs across the health-care market, including Medicare Part D, Managed 
Medicaid, and Fee-For-Service Medicaid.

    By aligning payments for medicines more directly with their value 
in improving meaningful health outcomes and/or reducing the need for 
other health-care services (such as hospitalizations), VBAs make 
pharmaceutical manufacturers accountable for the results their products 
achieve in a concrete way and can help improve patients' health and 
maximize the benefits of health-care spending. A recent Avalere survey 
of payers found that 44 percent of payers engaged in outcomes-based 
contracts experienced improvements in patient outcomes.\8\
---------------------------------------------------------------------------
    \8\ Avalere Health. ``Outcomes-Based Contracts: Payer 
Perspectives.'' Avalere Policy 360. July 19, 2018.

    VBAs also can increase patient access to new therapies which could 
ultimately improve patient outcomes. A payer that might otherwise 
decline to cover a new medicine (or that would only cover the medicine 
with significant utilization management restrictions or high cost 
sharing) due to uncertainties about the expected percentage of its 
patient population who would benefit might increase access to the 
medicine if the manufacturer shared the risks of the medicine's 
performance. These agreements may make medicines more accessible to 
patients who will benefit from them and increase competition in 
relevant therapeutic classes.\9\ Researchers have found that value-
based arrangements can improve patient access to medicines.\10\
---------------------------------------------------------------------------
    \9\ Staley, L. ``A Drug's Worth: Why Federal Law Makes it Hard to 
Pay for Pharmaceutical Performance.'' Boston University Law Review. 
2018;98(1):303-334. (``Tying reimbursement to health outcomes presents 
new opportunities for competition with rival manufacturers. . . . [A] 
manufacturer that can demonstrate sustained health benefits in post-
market studies may distinguish itself from competitors.'').
    \10\ See, for example, description of Entresto and Repatha 
contracts in: Seely, E., and Kesselheim, A. ``Outcomes-Based 
Pharmaceutical Contracts: An Answer to High U.S. Drug Spending?'' 
Commonwealth Fund. Issue Brief. September 2017.

    While Merck has had some experience with VBAs, these efforts have 
not been as robust as they could be due to the challenges involved in 
developing and implementing them. In addition to infrastructure and 
data limitations, challenges include regulatory limitations such as 
government pricing frameworks (e.g., Medicaid Best Price (BP) rules, 
---------------------------------------------------------------------------
Medicare's Average Sales Price (ASP)) and Federal fraud and abuse laws.

    Accordingly, we support opportunities that would enable greater 
experimentation in the design, structure, and implementation of VBAs. 
Further innovation in this space is needed to support overall sponsor 
and plan learning, and to determine the range of potential benefits to 
diverse health systems and beneficiaries. To fully achieve these goals, 
however, the impacts of the current regulatory framework, including 
government pricing requirements, the Federal Anti-Kickback Statute 
(AKS), and overall environmental barriers, must be analyzed and 
addressed as appropriate. Policy solutions such as the Patient 
Affordability Value and Efficiency Act (PAVE), introduced by Senators 
Warner and Cassidy, could provide necessary regulatory flexibility for 
properly structured VBAs.
                       transparency/point of sale
    Question. In almost all of your testimonies, you express your 
support for the Trump administration's proposal to allow manufacturers 
to provide PBMs up-front discounts that are passed onto patients at the 
point-of-sale.

    Do you feel like this proposal will make the transactions within 
the drug supply chain more transparent?

    If so, would this transparency bring down drug costs--overall and 
for specialty drugs?

    Answer. We believe we must change the system to ensure that 
patients receive the benefit of the significant rebates and discounts 
that manufacturers like Merck pay to PBMs and plans. The proposed rule 
is a positive step in that direction. Based on our initial assessment 
of the proposal, we believe that it will remove misaligned incentives 
within the system, drive more transparency in the system, and most 
importantly, lower beneficiaries' out-of-pocket costs.
         the relationship between wholesalers and manufacturers
    Question. When talking about the pharmaceutical supply chain, a lot 
of focus has been placed on the Pharmacy Benefit Manager. But there's 
another side of the equation that I'd like to ask about.

    How do wholesalers negotiate pricing with manufacturers?

    What impact does this have on drug costs?

    What incentives or disincentives do they have to contain price 
increases?

    Answer. There are many entities supporting the distribution and 
dispensing of pharmaceutical products. Wholesalers purchase 
pharmaceutical products directly from manufacturers and subsequently 
sell those products to sites of care for dispensing. Downstream 
customers of the wholesalers include retail and specialty pharmacies, 
hospitals, clinics, and others. Those entities that purchase from the 
wholesalers ultimately dispense or administer the drug to patients.

    Many manufacturers typically offer a ``prompt pay'' discount to 
wholesalers in exchange for timely payment of invoices (2 percent for 
payment within 30 or 35 days is fairly standard in the industry).

    Manufacturers also contract with wholesalers for services that 
support the appropriate storage and distribution of product to 
appropriate customers within the supply chain. These ``Distribution 
Service Agreements'' provide wholesalers with an opportunity to earn 
fees based on performance against pre-defined metrics that are part of 
a set of standard services. These services include managing inventory 
levels, achieving defined service levels, consolidating receipt of 
inventory to a central location, and administering contract pricing and 
chargebacks. Although these distribution service fees manufacturers pay 
to wholesalers are commonly administered as a percent of the list 
price, they are negotiated at arm's length and are based on fair market 
value for the services rendered.

    The terms of wholesaler agreements with their downstream customers 
vary; however, in general, the prices they offer to their customers are 
set relative to a product's list prices. In general, fees paid to 
wholesalers by manufacturers are modest and wholesaler economics 
(including both buy and sell side) are not likely to influence the 
setting of a product's list price.

                                 ______
                                 
                 Questions Submitted by Hon. Ron Wyden
                          proposed rebate rule
    Question. As has been done in many other settings, drug 
manufacturers said during the hearing that one reason list prices for 
drugs are high is that pharmaceutical benefit managers (PBMs) demand 
larger and larger rebates in order for the drug to receive favorable 
placement on a formulary. You and your colleagues who testified during 
the hearing stated if the administration's proposal on changes to the 
anti-kickback safe harbor for pharmaceutical rebates took effect, your 
company would likely lower list price.

    Like many Oregonians, I am skeptical drug manufacturers would 
voluntarily lower their prices. Therefore, would you support 
legislation that would (1) make similar changes the administration has 
put forward related to Part D and Medicaid managed care, (2) change the 
rebate system in a similar way to the proposal for the commercial 
market, and (3) require drug makers to lower the list price of their 
drugs equal to the amount of rebates provided today?

    Answer. We believe we must change the system to ensure that 
patients receive the benefit of the significant rebates and discounts 
that manufacturers like Merck pay to PBMs and plans. The proposed rule 
is a positive step in that direction. Based on our initial assessment 
of the proposed rule, we believe that it will remove misaligned 
incentives within the system, drive more transparency in the system, 
and most importantly, lower beneficiaries' out-of-pocket costs. Merck 
supports the earliest possible implementation of the proposed rule that 
can be achieved without creating disruption for the beneficiaries who 
rely on Medicare for their drug coverage. We are committed to working 
with the PBMs and health plans and other intermediaries to make this 
happen.

    We do not support legislation to require manufacturers to lower 
their list price equal to the amount of rebates today. First, different 
purchasers receive different levels of discounts, based on 
individualized negotiations and the formulary positioning of Merck's 
products. So, there is not a uniform ``rebate amount'' that could 
reduce the list price. Moreover, we expect that the robust negotiations 
that occur today will continue in the highly competitive Part D market, 
and we expect to realize the same level of net price that we do today. 
In fact, we expect that there could be additional pricing pressure 
under the new system, which could lead to lower net prices.

    Over time, we expect that our list prices will go down if the 
misaligned incentives across the system are addressed. We are currently 
working with other stakeholders in the system to solve the operational 
challenges that will enable these changes.

    But, it is also important to note that if the rule is implemented, 
Medicare beneficiaries' out-of-pocket costs will be reduced, 
independent of any lowering of list prices, since their cost-sharing 
will be based on the net price. Nonetheless, we believe the rebate rule 
will align incentives in a way that will restrain list prices.

    As we stated when we reduced the list price of several of our 
products in July 2018, we have continued to look for opportunities to 
reduce our list prices. We think the proposed rule would help create 
those opportunities, but it can't happen overnight. All the players in 
the ecosystem will need to adjust to the new model. We are actively 
working to support the move to a contracting model in Part D that would 
change the incentives to support lower list prices.

    Lowering list prices is not an easy thing to do in our health-care 
system:

          One of the key challenges to lowering list prices is the 
        contractual arrangements that companies have with PBMs and 
        health plans, which are intended to ensure access to our 
        products. These contracts are often multi-year and are most 
        often written to provide a discount off of the list price, 
        which is paid as a rebate later.

          To reduce the list price without significant financial 
        consequences, all of these contracts would need to be modified 
        to maintain the same net price. Unless the entire system 
        changes, one manufacturer runs the risk of being disadvantaged 
        and losing formulary status or being required to pay the same 
        percentage discount on a lower list, which could be 
        unsustainable.

          In addition, drugs flow through a complex supply chain, from 
        the manufacturer, to the wholesaler, to a pharmacy or hospital 
        who dispenses the drug to patients. For any product but even 
        more so for a high volume primary care product that is flowing 
        through to all pharmacies and hospitals, there is not a 
        mechanism in place to readjust the value of the inventory being 
        held by all those parties.

    If the proposed rule is implemented as written, it would only apply 
to our contracts with PBMs and health plans for Medicare Part D and 
Managed Medicaid. If PBMs and health plans maintain the rebate model in 
the commercial market, we would still have commercial contracts based 
on rebates, which would be subject to the existing constraints to 
lowering list price. We also would still need a mechanism to revalue 
drug in the distribution channel in a financially viable manner.
                      medicaid drug rebate program
    Question. The Medicaid Drug Rebate Program (MDRP) requires 
manufacturers to provide a basic rebate and an additional inflationary 
rebate for both brand and generic drugs. The inflationary rebate is an 
increasingly substantial part of total rebates due in large part to 
large increases in drug prices that exceed inflation. Under current 
law, this inflationary rebate is capped at 100 percent of Average 
Manufacturer Price (AMP). This is the case even when manufacturers 
continue to raise their prices well above inflation.

    Please provide a list of all of your pharmaceutical products that 
have reached the Medicaid AMP rebate cap in any of the 20 quarters from 
January 1, 2014 through December 31, 2018.

    For each drug listed in response to question 1, please also provide 
a list of which quarters and years each drug hit the cap.

    Answer. Merck conforms to all statutory, regulatory, and sub-
regulatory guidance regarding its participation in the Medicaid Drug 
Rebate Program, including the payment of Medicaid rebates. The 
information requested by this question, however, is confidential, 
proprietary, and commercially and competitively sensitive. Merck would 
be happy to explore other means to share this information with the 
committee in a confidential fashion.
                medicaid drug rebate program compliance
    Question. I am concerned about recent reports and legal settlements 
surrounding drug manufacturers' failure to comply fully with the 
requirements of the MDRP. For example, an analysis by the U.S. 
Department of Health and Human Services Office of Inspector General 
found that between 2012 and 2016 taxpayers may have overpaid by as much 
as $1.3 billion for 10 potentially misclassified drugs. That is why I 
introduced the Right Rebate Act with Chairman Grassley to prevent drug 
manufacturers from manipulating Medicaid to increase their profits. 
However, I continued to be concerned about oversight and manufacturer 
compliance with the requirements of the Medicaid Drug Rebate Program. 
Accordingly, please describe the following:

    Your company's current compliance plan and procedures used to 
ensure compliance with the requirements of the Medicaid Drug Rebate 
Program including internal audits or other checks you use to identify 
compliance vulnerabilities.

    Answer. Merck's government price reporting team--in consultation 
with in-house attorneys, outside counsel, and third-party vendors as 
appropriate--maintains comprehensive and detailed government price 
reporting policies, procedures, and reasonable assumptions for 
compliance with all price reporting programs, including the Medicaid 
Drug Rebate Program (MDRP). Merck's policies are evaluated and updated, 
as needed, on an annual basis by the government price report team, in-
house attorneys, and outside counsel to ensure that they are consistent 
with current regulations and applicable guidance from the Centers for 
Medicare and Medicaid Services (CMS). Additionally, Merck's reasonable 
assumptions are evaluated and updated, as needed, on a monthly basis 
for Average Manufacturer Price and on a quarterly basis for Best Price 
by the government price reporting team, in-house attorneys, and outside 
counsel. Merck has a long history of transparency and communication 
with CMS regarding its MDRP compliance and reasonable assumptions, and 
company compliance personnel regularly oversee Merck's price reporting 
operations. Merck evaluates any new guidance issued by CMS to ensure 
that its price reporting calculations and processes are in compliance 
with the law.

    Question. Any past or ongoing issues of non-compliance.

    Answer. Merck maintains comprehensive and detailed reasonable 
assumptions for its MDRP participation. In situations in which Merck is 
uncertain about a calculation approach that is not clearly addressed in 
CMS rules or guidance, the company documents its approach in 
assumptions and/or discloses its intended approach to CMS. 
Additionally, given the complexity of the calculations, Merck may 
identify calculation mistakes or other issues that require correction. 
This may happen, for example, to the extent that Merck believes that 
any new CMS rules or guidance call into question a reasonable 
assumption that the company has previously maintained. In such cases, 
if Merck has any concern about its program compliance, it promptly 
communicates with CMS to seek the agency's guidance and potentially 
restate its prior MDRP reports.

    Question. Any corrective actions taken to address identified 
problems or issues of non-compliance with the MDRP and how such steps 
were communicated to the Centers for Medicare and Medicaid Services.

    Answer. As noted above, to the extent that Merck believes that any 
of its existing calculation or compliance processes for MDRP 
participation are not in keeping with current CMS rules or guidance, 
the Company would promptly engage with the agency to identify any 
necessary remedial steps and the appropriate way forward, including 
filing pricing restatements.

    Question. Any steps taken to improve compliance and ensure that all 
Medicaid drug rebates owed to the Federal Government and the States are 
paid in full.

    Answer. As noted above, Merck takes its government price reporting 
obligations very seriously, and the Company maintains robust, ongoing 
legal and compliance oversight of its price reporting team and its 
operations. As discussed above, we routinely review our policies, 
procedures, and reasonable assumptions to ensure compliance with 
current law. Merck also has an annual training requirement for 
government price reporting compliance. If Merck were to identify any 
potential noncompliance issue associated with the underpayment of 
rebates to the State Medicaid Programs, Merck immediately would 
identify this issue to CMS and would work with the agency to ensure the 
implementation of any appropriate remedy (including restating pricing 
metrics and reconciling rebate amounts with the States).
                 bonus payments tied to specific drugs
    Question. I am concerned by the potential for employee financial 
incentives to encourage high launch prices and price increases for 
prescription drugs.

    Is your salary, bonus, or other compensation tied to sales or 
revenue targets of a single product your company sells? Has it ever 
been? If yes, please state the product or products to which your 
salary, bonus, or other compensation was tied.

    Answer. My salary, bonus, or other compensation is not tied to 
sales or revenue targets of a single product that Merck sells. In 2011, 
a very small percentage of my annual bonus was tied to the net sales of 
3 new products (DULERA, SIMPONI, and VICTRELIS).

    Question. Is your salary, bonus, or other compensation tied to 
either revenue or net income of the company as a whole? Has it ever 
been? If yes, please explain what assumptions about price increases are 
used when the compensation committee sets revenue or net income goals. 
Does the compensation committee provide any guidance to executives in 
regards to the amount of revenue that the company will generate from 
price increases versus volume growth?

    Answer. Yes, a portion of my annual bonus is tied to revenue and 
pretax income (i.e., a variation of net income) of the company as a 
whole, with each contributing 40 percent (for a total of 80 percent) to 
the aggregate incentive target, and research and development 
productivity constituting the other 20 percent of the target. The final 
bonus that I receive is then calculated based on the company's actual 
performance for those three metrics.

    The Compensation and Benefits Committee of the Board sets annual 
targets for revenue and pretax income based upon the company's annual 
plan, as approved by the full Board of Directors.

    The company's annual plan includes U.S. pricing assumptions 
informed by several variables, including volume, price, and discount 
rates, which for 2019 are fully consistent with our July 19, 2018 
commitment to not increase net price across our product portfolio in 
the U.S. by more than inflation annually.

    Neither the board of directors as a whole, nor the Compensation and 
Benefits Committee specifically, provides guidance to executives with 
regard to the amount of revenue that the company will generate from 
price increases versus volume growth.
                               net prices
    Question. In your testimony, you stated, ``last year we pledged 
that we will not increase our average net prices for our portfolio by 
more than the rate of inflation annually,'' and that ``From 2010 to 
2017, Merck's average net price increase across our portfolio each year 
has been in the low to mid-single digits. In fact, our average net 
price declined in 2017 by almost 2 percent. In 2017, the average 
discount for our medicines and vaccines was more than 45 percent lower 
than the list price.'' Please describe how the company's year-over-year 
aggregate net price is calculated. Please also specifically address the 
following questions:

    Answer. Net Price Change represents the year-over-year change in 
average net price, which is Wholesale Acquisition Cost (WAC) less 
rebates, discounts, and returns. The annual percent change versus prior 
year was calculated at a product level and weighted across the 
company's U.S. Product Portfolio. U.S. Product Portfolio includes human 
health pharmaceutical and vaccine products marketed by the company, 
excluding partnered products. The product sales utilized in the 
analysis represent 97 percent of the total U.S. Product Portfolio in 
2010, increasing each year to approach 99.8 percent of coverage in 
2017.

    Question. How many products are included in the calculation of the 
average net price change? What was the median net price change?

    Answer. In 2017, 78 products were included. The median net price 
change was 0 percent.

    Question. Is net price weighted? If so, how? For example, in 
determining the aggregate net price does the company assign different 
weights to different products based on volume or other factors? Are 
``on patent'' and ``off patent'' drugs weighted identically? Are other 
statistical weights used or are all products treated equally?

    Answer. The Net Price Change percent for each product is weighted 
by its Net Sales relative to the Total Net Sales of the Product 
Portfolio for the current year. On and off patent drugs are calculated 
in the same fashion, and no other ``statistical weighting'' is applied.

    Question. Does the figure that you provided during your testimony 
account for U.S. prices, international prices, or both? Generally 
speaking, when your company reports net price changes, does it 
differentiate between U.S. and international prices?

    Answer. Only U.S. prices are used in the report.

    Question. Please list the five drugs your company sold in the U.S. 
that had the greatest year-over-year net price increase in 2018, noting 
the increase for each drug by dollar figure and percentage. Please list 
the five drugs your company sold in the U.S. that had the lowest year-
over-year net price increase (and/or the greatest decrease) in 2018, 
noting the increase (or decrease) for each drug by dollar figure and 
percentage.

    Answer. The product-specific information requested is competitively 
sensitive and Merck therefore cannot produce it in a public setting in 
which it could be accessed by competitors. However, Merck does report 
similar information in an aggregated format in its annual price 
transparency report, which we proactively make available on our 
corporate responsibility website:

    https://s3.amazonaws.com/msd18-assets/wp-content/uploads/2019/02/
281553
45/2018-US-PRICING-TRANSPARENCY-REPORT_02.2019.pdf

    The report sets forth the average annual list price changes across 
the Merck portfolio as well as other price related information 
concerning Merck medicines and vaccines. The report shows that in 2018 
the average annual list price across the Merck portfolio increased by 
5.5 percent--the lowest increase since 2010--as compared with a 6.6 
percent increase in 2017. In 2018, the Company's gross U.S. sales were 
reduced by 44.3% as a result of rebates, discounts and returns. The 
below chart reflects additional information about the price changes for 
Merck products.

                              U.S. Product Portfolio Percent Change vs. Prior Year
----------------------------------------------------------------------------------------------------------------
                                                   2010   2011   2012   2013   2014   2015   2016   2017    2018
----------------------------------------------------------------------------------------------------------------
List Price Change (WAC)                             7.4    9.5    9.2    9.6   10.5    9.8    9.6     6.6    5.5
----------------------------------------------------------------------------------------------------------------
Net Price                                           3.4    5.1    6.2    5.5    3.7    5.5    5.5   (1.9)   2.99
----------------------------------------------------------------------------------------------------------------
                                             U.S. Product Portfolio
----------------------------------------------------------------------------------------------------------------
Average Discount (%)                               27.3   28.9   29.9   32.1   37.0   38.2   40.9    45.1   44.3
----------------------------------------------------------------------------------------------------------------

    Question. For 2018, what was the average net price change in the 
U.S. market for (1) drugs with no competition, (2) drugs with only 
branded competition, and (3) drugs with generic competition?

    Answer. The product-specific information requested is competitively 
sensitive and Merck therefore cannot produce it in a public setting in 
which it could be accessed by competitors. However, Merck does report 
similar information in an aggregated format in its annual price 
transparency report, which we proactively make available on our 
corporate responsibility website:

    https://s3.amazonaws.com/msd18-assets/wp-content/uploads/2019/02/
281553
45/2018-US-PRICING-TRANSPARENCY-REPORT_02.2019.pdf

    The report sets forth the average annual list price changes across 
the Merck portfolio as well as other price related information 
concerning Merck medicines and vaccines. The report shows that in 2018 
the average annual list price across the Merck portfolio increased by 
5.5 percent--the lowest increase since 2010--as compared with a 6.6-
percent increase in 2017. In 2018, the company's gross U.S. sales were 
reduced by 44.3% as a result of rebates, discounts and returns. The 
below chart reflects additional information about the price changes for 
Merck products.

                              U.S. Product Portfolio Percent Change vs. Prior Year
----------------------------------------------------------------------------------------------------------------
                                                   2010   2011   2012   2013   2014   2015   2016   2017    2018
----------------------------------------------------------------------------------------------------------------
List Price Change (WAC)                             7.4    9.5    9.2    9.6   10.5    9.8    9.6     6.6    5.5
----------------------------------------------------------------------------------------------------------------
Net Price                                           3.4    5.1    6.2    5.5    3.7    5.5    5.5   (1.9)   2.99
----------------------------------------------------------------------------------------------------------------
                                             U.S. Product Portfolio
----------------------------------------------------------------------------------------------------------------
Average Discount (%)                               27.3   28.9   29.9   32.1   37.0   38.2   40.9    45.1   44.3
----------------------------------------------------------------------------------------------------------------

    Question. In Merck's most recent pricing transparency report, the 
company notes that the ``the average annual net price across our 
portfolio declined by 1.9 percent, reflecting specific in-year 
dynamics, including the impact of loss of patent protection for three 
major medicines.'' Please identify these medicines, and the net price 
change for each of them on a dollar and percentage basis for 2017. What 
was Merck's average net price increase/decrease in 2017 for drugs 
excluding these three medications?

    Answer. This information is confidential, proprietary, and 
commercially sensitive. Merck's average net price increase/decrease in 
2017 excluding the three drugs referred to is -0.6 percent.

    Question. In Merck's pricing transparency report, the company 
states that its net price is ``represents the year-over-year change in 
average net price, which is WAC less rebates, discounts and returns,'' 
while its average discount is ``weighted . . . [and] calculated by 
dividing annual rebates, discounts and returns by annual gross sales.'' 
Please clarify whether the company's average net price is weighted for 
purposes of complying with its publically stated pledge.

    Answer. Yes, the average net price is weighted.

                                 ______
                                 
              Questions Submitted by Hon. Robert Menendez
    Question. When new products enter the market, do drug companies set 
high initial rebates and then provide deep rebates in order to gain 
access to insurance plan's formularies?

    Answer. Merck approaches pricing from the perspective of value. 
This approach looks at the value that a medicine provides through 
multiple lenses with the goal of reflecting its benefit to patients and 
to society, while at the same time paying an appropriate return on 
invested capital to our investors, to ensure that we are able to 
sustain R&D. While each individual situation varies based on factual 
circumstances and market dynamics, generally, we consider:

          Value provided to patients--to what extent does a new 
        medicine or vaccine establish a new standard of care that has 
        the potential to significantly extend and improve patient 
        lives?

          Value provided to health-care systems--to what extent does a 
        new medicine or vaccine reduce the costs associated with 
        hospitalization and other costly complications of disease if 
        not appropriately (or optimally) treated?

          Unmet need--does a new medicine or vaccine address a 
        critically unmet medical need, where few or no treatments 
        exist?

          Access--what is the ability of various customers around the 
        world--including national, regional or local institutional 
        payers, physicians, employers and patients--to pay for our 
        products?

          R&D sustainability--given the long-term risk and cost of 
        capital, can we appropriately compensate our investors to 
        ensure continued investment in the kind of risky and capital-
        intensive research and development that will bring forward 
        medically important breakthroughs?

          Competition--what are the costs of other treatments 
        currently on the market relative to the value provided by 
        Merck's products?

    When the company launched ZEPATIER into the Hepatitis C market, 
Merck chose a low list price strategy, while competitors had a higher 
price with significant rebates. Unfortunately, we were unable to gain 
reasonable formulary status or resulting sales in certain market 
segments with this strategy. Positive actions in the U.S., such as the 
administration's proposal regarding the rebate safe harbor could 
provide incentives for lower initial list prices in the future.

    Question. If CMS finalizes the rebate rule, do you anticipate 
future products entering the market with significantly lower initial 
list prices?

    Answer. Over time, we expect that list prices will go down if you 
remove the misaligned incentives in the system. It is also important to 
note that if the rule is implemented, Medicare beneficiaries' out-of-
pocket costs will be reduced--independent of any lowering of list 
prices--since their cost-sharing will be based on the net price. But we 
believe the rebate rule will align incentives in a way that will 
restrain list prices.

    If this rule is implemented as written, it would only apply to our 
contracts with PBMs and health plans for Medicare Part D and Managed 
Medicaid. If PBMs and health plans maintain the rebate model in the 
commercial market, we would still have commercial contracts based on 
rebates, which would be subject to the existing constraints to lowering 
list price. We also would still need a mechanism to revalue drug in the 
distribution channel in a financially viable manner.

                                 ______
                                 
              Questions Submitted by Hon. Thomas R. Carper
    Question. What are your recommendations for lowering prices for the 
40 percent of drugs that do not offer rebates in Medicare Part D?

    Answer. Assuming the 40 percent reference is correct, we believe 
that the administration's rebate safe harbor proposal will lead to 
lower prices even for products which currently may offer no or minimal 
rebates in Medicare Part D. We believe the increasing transparency of 
prices will spur heightened competition even in classes and for 
products where rebating has been limited in the current system. 
Similarly, the fact that price concessions will be made directly 
available to patients will also create a price-reducing dynamic since 
price concessions will make products more affordable to patients, 
resulting potentially in greater adherence and appropriate use of 
prescribed medicines, clearly benefiting patients and encouraging 
manufacturers to offer price concessions. Additionally, assuming policy 
changes are made to further incentivize value-based contracts, we 
believe that value-based contracts can also help to restrain initial 
list prices by tying those prices to the value that the products bring 
to patients and the health-care system.

    Question. In the health insurance plans that you offer your 
employees, do you ask your insurers to pass through the full 
manufacturer rebates to the beneficiaries?

    Answer. Merck offers a generous health-care benefit for our 24,000 
U.S. employees. There is no deductible for medications covered under 
our pharmacy benefit, and employees never have to pay more than $50 for 
a retail prescription for a covered medication, and in most cases pay 
less. We contract with a PBM for management of the prescription drug 
benefits for our employees, and the benefit does not offer point-of-
sale rebates to our employees. Merck uses savings generated by rebates 
to lower overall costs for employees while ensuring low out-of-pocket 
costs.

    Question. The systems for pricing and distributing drugs are opaque 
and difficult to understand. What are your recommendations for 
increasing transparency in how your companies set the list prices for 
drugs, and for improving transparency in the supply chain for 
prescription drugs? Would you support Federal standards for 
transparency in setting the list prices for drugs?

    Answer. We are open and transparent about the factors we consider 
in setting prices. Merck approaches pricing from the perspective of 
value. This approach looks at the value that a medicine provides 
through multiple lenses with the goal of reflecting its benefit to 
patients and to society, while at the same time paying an appropriate 
return on invested capital to our investors, to ensure that we are able 
to sustain R&D. While each individual situation varies based on factual 
circumstances and market dynamics, generally, we consider:

          Value provided to patients--to what extent does a new 
        medicine or vaccine establish a new standard of care that has 
        the potential to significantly extend and improve patient 
        lives?

          Value provided to health-care systems--to what extent does a 
        new medicine or vaccine reduce the costs associated with 
        hospitalization and other costly complications of disease if 
        not appropriately (or optimally) treated?

          Unmet need--does a new medicine or vaccine address a 
        critically unmet medical need, where few or no treatments 
        exist?

          Access--what is the ability of various customers around the 
        world--including national, regional or local institutional 
        payers, physicians, employers and patients--to pay for our 
        products?

          R&D sustainability--given the long-term risk and cost of 
        capital, can we appropriately compensate our investors to 
        ensure continued investment in the kind of risky and capital-
        intensive research and development that will bring forward 
        medically important breakthroughs?

          Competition--what are the costs of other treatments 
        currently on the market relative to the value provided by 
        Merck's products?

    Question. In nearly every sector of the health-care industry, 
Medicare, Medicaid, employers, and insurers are moving away from fee-
for-service payments to reimbursements based on value and performance. 
Prescription drugs and medical devices were the glaring exceptions to 
this trend until recently. How many of your drugs are included in 
value-based contracts and how many patients are benefiting from them? 
How do these value-based contracts work to lower drug prices for both 
patients and taxpayers?

    Answer. Merck has been party to value-based discounting 
arrangements for four of its products. It is difficult to assess 
exactly how many patients have benefitted from them, however, since 
that information is not in Merck's possession under the arrangements.

    Merck agrees that value-based discounting strategies can benefit 
patients and the Federal health care programs by ensuring that payment 
aligns with the value or outcomes that a manufacturer's products bring 
to the system. If, for example, a value-based agreement demonstrates 
that a manufacturer's product helps patients to achieve meaningful 
clinical outcomes (or even to avoid more serious illness complications 
or comorbidities), the product would have demonstrated a savings to 
patients and taxpayers (for example, by avoiding hospitalization or 
further treatment for a particular condition). There are, however, 
significant impediments under current law regarding adopting this type 
of contract--including under the Anti-Kickback Statute and manufacturer 
government price reporting obligations--and Merck supports legislative 
or regulatory reforms to increase the proliferation of value- or 
outcomes-based discounting.

    Question. Last year, Senator Portman and I did an investigation on 
the pricing of an opioid overdose reversal drug called EVZIO, 
manufactured by Kaleo. Kaleo increased the price of EVZIO from $575 in 
2014 to $4,100 in 2017. We found that the best price Medicare was able 
to get for EVZIO, about $4,000, was much higher than the price other 
Federal programs and private insurers were able to get. It seemed that 
Kaleo was able to get this higher price of $4,000 from Medicare by 
helping doctors fill out paperwork showing that the drug was medically 
necessary, even though there are cheaper alternatives on the market. As 
a result of the investigation, Kaleo announced it will bring a generic 
version of the drug to market at only $168 per pack. Are any of your 
companies providing medical necessity paperwork to doctors in order to 
get your drugs covered by Medicare?

    Answer. In the United States, Merck provides limited reimbursement 
support for patients in connection with the purchase of certain of 
Merck's products following a physician's prescribing decision (in 
accordance with Department of Health and Human Services Office of 
Inspector General guidance). In certain cases, this support includes 
identifying--for patients and physicians--the appropriate forms and 
insurance processes attendant to securing insurance coverage for our 
products. But it is Merck's policy never to interfere with the 
physician-patient relationship or the decision about whether to seek 
insurance coverage.

    Question. In 2017, the Rand Corporation estimated that biosimilar 
drugs, which are competitors to complex, biologic drugs, could save the 
United States more than $50 billion over the next decade. Some of you 
have also argued that increasing the use of biosimilar drugs would help 
lower drugs costs for consumers and taxpayers. What is delaying the 
uptake of biosimilar drugs in the United States? What policies do you 
recommend to increase the development of biosimilar drugs?

    Answer. Merck agrees that we can significantly reduce spending on 
pharmaceuticals, especially for patients, by ensuring that we have a 
viable market for biosimilars in the United States. We believe, like 
with traditional small molecule medicines, generic competition after a 
reasonable period of exclusivity will create headroom for patients to 
afford the newest, most innovative medicines. In addition to the RAND 
data that you referenced, other research shows that generics and 
biosimilars are expected to drive savings of $105 billion through 2022 
in the U.S.\11\
---------------------------------------------------------------------------
    \11\ IQVIA. ``Medicine Use and Spending in the U.S.: A Review of 
2017 and Outlook to 2022.'' (Apr. 19, 2018), https://www.iqvia.com/
institute/reports/medicine-use-and-spending-in-the-us-review-of-2017-
outlook-to-2022.

    We suggest the following policy changes to help encourage and 
---------------------------------------------------------------------------
support prescriber biosimilar utilization:

          Consider options to reduce or eliminate patient cost sharing 
        in Medicare Part B for biosimilars. While some Part B 
        beneficiaries are already able to reduce their 20 percent cost 
        sharing via supplemental coverage, we believe eliminating cost 
        sharing will encourage many physicians to use biosimilars for 
        their patients. A similar approach in Part D and in Medicaid 
        for small-molecule generics has driven generic utilization up 
        to 90 percent.\12\
---------------------------------------------------------------------------
    \12\ Department of Health and Human Services. Office of Inspector 
General. ``Generic Drug Utilization in the Medicare Part D Program.'' 
(Nov. 2007), https://oig.hhs.gov/oei/reports/oei-05-07-00130.pdf.

          Create pathways for MA and Part D plans to receive bonus 
        payments and/or enhanced star ratings for achieving metrics 
        related to access to biosimilars. This will incentivize plans 
        to implement policies that drive additional utilization of 
---------------------------------------------------------------------------
        biosimilars.

          Consider alternative reimbursement methodologies that adjust 
        the current Part B reimbursement formula. The current structure 
        in Part B to reimburse at ASP + 6 percent of the reference 
        product ASP ensures there is no reimbursement downside to 
        physicians for using biosimilars. But so far, the evidence does 
        not suggest the current reimbursement rate sufficiently 
        incentivizes providers to use biosimilar products. The 
        administration should consider alternatives to further 
        incentivize physician adoption of biosimilars.

                                 ______
                                 
             Questions Submitted by Hon. Benjamin L. Cardin
    Question. The United States is one of the only countries in the 
world to allow prescription drug manufacturers to advertise directly to 
consumers through magazines, billboards, radio, and television 
commercials. While I will not argue that it is beneficial to educate 
consumers about an unfamiliar disease and encourage them to seek 
medical help, most commercials from all of your companies recommend 
asking about a specific brand name drug, not a medical condition. 
Furthermore, even if your advertisements follow all FDA rules and list 
medication side effects, they also almost always list these while a 
smiling, apparently healthy person is walking on a beach.

    Researchers say that this type of imagery, combined with viewing 
hours of drug commercials each month, leads consumers to underestimate 
the risks associated with medications. For the past decade, studies 
have shown that aggressive direct-to-consumer advertising is associated 
with rising drug prices and an increase in inappropriate drug 
prescriptions.

    Since researchers have concluded that consumers are 
misunderstanding the benefits and risks described in your ads, what 
further policies could help you and your colleagues ensure that you are 
educating patients in a clear manner?

    Answer. Merck believes that direct-to-consumer (DTC) advertising 
can be an important and helpful way to inform patients about diseases 
that may be relevant to them and therapeutic options they may want to 
discuss with their physician. Data demonstrate that DTC can have a 
positive impact on patient health in terms of diagnosis, treatment, and 
adherence to prescribed therapies. We recognize that DTC is one channel 
amongst many to help educate patients. Print materials, telephone, 
websites, and other channels are also used to provide more in-depth 
information to patients. The ultimate decision to prescribe a product 
for any specific patient remains with the physician following 
discussion with their patient.

    Merck adheres to FDA regulations and guidelines governing DTC 
promotion and has a long-standing policy to voluntarily submit new DTC 
broadcast advertising campaigns to FDA for pre-review. Merck also 
follows the PhRMA Guiding Principles for DTC Advertisements About 
Prescription Medicines. We are currently considering what additional 
information we can make available to consumers to ensure that they can 
make informed health care decisions.
           pharmaceutical companies continue to raise prices
    Question. As you are well aware, high prescription drug prices are 
the number one concern for Americans and their families. According to 
the Organization for Economic Cooperation and Development, the average 
American spends around $1,208 annually on prescription drugs. There 
have been several instances where brand name or even generic drugs that 
have been on the market for years continue to increase in price.

    One of the most well-known examples is Mylan's increase of the 
price of EpiPen from less than $100 in 2007 to more than $600 in 2016. 
Another example is the ever-increasing price of insulin. Sanofi 
increased the price of a vial of Lantus from $88.20 in 2007 to $307.20 
in 2017. And those are just a small sample of price increases.

    Why don't we see price decreases for drugs that have been on the 
market for years without new formulations or added benefit?

    Answer. List prices do not generally decline largely owing to many 
of the misaligned incentives that the administration's rebate safe 
harbor proposal is designed to address. Specifically, rebate contracts 
for commercial and Medicare Part D payers/PBMs are designed as set 
percentages from the list price. Lowering list prices while maintaining 
these same percentage discounts/rebates usually precludes the 
commercial viability of reducing list prices.

    We do in fact see price decreases for products that have been on 
the market for years--extremely large ones. They occur at the time of 
patent expiry, and often reduce prices by over 90 percent. This is 
unlike any other part of the health care system we are aware of, where 
prices drop massively after a specified period. If these massive one-
time price reductions occurred more gradually, it would be far more 
obvious that prices were decreasing. Even putting this aside, net 
prices on many products drop dramatically over time as competition from 
new products increases. For instance, the average net price of our 
anti-diabetes medicine Januvia is less today than it was when it was 
launched in 2007.
                             pay for delay
    Question. Pay for delay is a tactic that more and more branded drug 
manufacturers have been using to stifle competition from lower-cost 
generic manufacturers. This allows you to sidestep competition by 
offering patent settlements that pay generic companies not to bring 
lower-cost alternatives to market.

    These ``pay-for-delay'' patent settlements benefit both brand-name 
pharmaceutical companies by helping them avoid costly patent litigation 
and general manufacturers by rewarding them a hefty sum to delay 
entering the market with a cheaper drug alternative. However, these 
deals do not benefit consumers. According to an FTC study, these 
anticompetitive deals cost consumers and taxpayers $3.5 billion in 
higher drug costs every year.

    Does your company partake in pay-for-delay settlements?

    Answer. Merck has not entered into patent settlement agreements 
with generic companies to delay their entry past when it would 
otherwise be lawful for them to enter the market. Merck has been party 
to a number of patent settlement agreements that provide for generic 
market entry prior to patent expiry, including some that have provided 
some level of exclusivity for a limited time. These agreements allowed 
generic products to enter the market earlier than would have otherwise 
been the case. The FTC has not challenged as anti-competitive any of 
these types of agreements involving Merck.

    Question. Why would a pharmaceutical company enter into a pay-for-
delay agreement?

    Answer. Parties enter into settlements of patent litigation for all 
the same reasons parties settle other civil litigation. These include 
allocation of risk in the dispute, avoidance of litigation costs, or 
beneficial access to technology from cross-licensing of the litigant's 
patents. Merck would be speculating as to why litigants would enter 
into settlements with large unjustified reverse payments.

    Question. Do you think these agreements stifle competition and 
prevent generic alternatives to your branded medications?

    Answer. Merck believes that the patent settlements it has made did 
not stifle competition nor unlawfully prevent generic alternatives to 
our patented medications.

    Patent settlement agreements in which a brand settles cases in a 
manner that allows a generic to enter the market prior to expiry of the 
brand's patents could actually accelerate patient access to lower cost 
alternatives. These settlements do not delay entry or cause the loss of 
any lawful competition because entry prior to the expiry of these 
patents would be unlawful infringement unless and until the generic 
manufacturers prevailed in court.

    Merck works within the statutory framework set by Hatch-Waxman and 
BPCIA to protect its intellectual property. We believe that patent 
holders have a valid right to enforce legitimate patents and that the 
courts are an appropriate venue to resolve such disputes.

    Our patents are a direct result of the investment we have made in 
R&D. When others seek to commercialize our innovations, Merck has 
engaged in litigation to enforce our patents.

    Merck is a strong supporter of bringing more generics to the 
market. It is important to remember that generics all started as a 
branded medication. A period of patent protection is provided for all 
new medicines as an incentive to research-based biopharmaceutical 
companies for the costly and risky research that is undertaken to 
develop them. Following the loss of patent protection, the medicines 
become low-cost generics that are available for many years, often 
decades into the future.

    Merck is proud that more than 40 million Americans annually benefit 
from our science in the form of generic medicines. Several of our 
discoveries--including cholesterol-lowering, heart disease, 
osteoporosis, and asthma treatments--are now widely available to a 
patient as generics, including some for about $20 per year, bringing 
billions of dollars in savings to consumers and the health care system.
                            drug rebate rule
    Question. In January, the Department of Health and Human Services' 
(HHS) Office of Inspector General (OIG) promulgated a new regulation to 
remove regulatory safe harbor protections under the Anti-Kickback 
Statute (AKS) for rebates on prescription drugs rebates paid by 
manufactures to PBMs under Medicare Part D and for Medicaid managed 
care organizations (MCOs). The OIG proposal attempts to ban most 
rebates by eliminating their regulatory protections.

    The rule is predicted to increase net drug costs in its early 
years. The CMS actuaries estimate it would cost $196 billion over 10 
years. Despite this high price tag, the beneficiary benefits are 
limited. The proposed rule notes that under the CMS Actuary's analysis, 
the majority of beneficiaries would see an increase in their total out-
of-pocket payments and premium costs; reductions in total cost sharing 
will exceed total premium increases.

    I wanted to ask a question about the administration's rebate rule, 
which I understand that many of the drug manufacturers, and your main 
trade association, strongly support. According to an analysis of the 
rule by the Office of Actuaries at CMS, drug manufacturers are likely 
to initially retain 15 percent of the current rebates as higher net 
drug prices.

    Given that estimate, can you provide the committee with any 
assurances that prices will not increase under this proposed rule?

    Answer. Over time, we expect that list prices will go down if the 
misaligned incentives across the system are addressed. It is also 
important to note that if the rule is implemented, Medicare 
beneficiaries' out-of-pocket costs will be reduced, independent of any 
lowering of list prices, since their cost-sharing will be based on the 
net price. Nonetheless, we believe the rebate rule will align 
incentives in a way that will restrain list prices.

                                 ______
                                 
               Questions Submitted by Hon. Sherrod Brown
    Question. According to an article recently published in the Journal 
of the American Medical Association, medical marketers spent nearly $30 
billion dollars in 2016, up from $17 billion in 1997. Direct-to-
Consumer (DTC) advertising had the biggest percentage increase: from 
$2.1 billion, or 11.9% of all medical marketing, in 1997 to $9.6 
billion, or 32% of total spending, in 2016.

    Can you please provide what your ratio of spending on sales and 
marketing to research and development is today?

    Answer. In 2018, Merck incurred $9.8 billion in research and 
development costs globally, the vast majority of which was conducted in 
the U.S. Since 2010, Merck has invested nearly $70 billion in R&D to 
create new medicines and vaccines that address the greatest health 
challenges of our time--including antimicrobial resistance, Ebola, HIV, 
and cancer--to save and improve lives around the world. In 2018, Merck 
spent about $2.3 billion in the U.S. market on direct marketing and 
selling expenses. This number includes all sales and marketing 
expenses, including creative development of resources and headcount 
related to all marketing and sales activity in the U.S. market.
                             price-gouging
    Question. Sanofi, as I understand it, has made a pledge to the 
public to limit its price increases to the national health expenditures 
growth projection.

    Would your company commit to a cap on annual price increases as 
part of your PhRMA membership criteria?

    Answer. In July 2018, Merck pledged to not increase the average net 
price across our portfolio by more than inflation annually.

    Question. What policies would you propose to help ensure lower 
launch prices for new drugs?

    Answer. Merck approaches pricing from the perspective of value. 
This approach looks at the value that a medicine provides through 
multiple lenses with the goal of reflecting its benefit to patients and 
to society, while at the same time paying an appropriate return on 
invested capital to our investors, to ensure that we are able to 
sustain R&D. While each individual situation varies based on factual 
circumstances and market dynamics, generally, we consider:

          Value provided to patients--to what extent does a new 
        medicine or vaccine establish a new standard of care that has 
        the potential to significantly extend and improve patient 
        lives?

          Value provided to health-care systems--to what extent does a 
        new medicine or vaccine reduce the costs associated with 
        hospitalization and other costly complications of disease if 
        not appropriately (or optimally) treated?

          Unmet need--does a new medicine or vaccine address a 
        critically unmet medical need, where few or no treatments 
        exist?

          Access--what is the ability of various customers around the 
        world--including national, regional or local institutional 
        payers, physicians, employers and patients--to pay for our 
        products?

          R&D sustainability--given the long-term risk and cost of 
        capital, can we appropriately compensate our investors to 
        ensure continued investment in the kind of risky and capital-
        intensive research and development that will bring forward 
        medically important breakthroughs?

          Competition--what are the costs of other treatments 
        currently on the market relative to the value provided by 
        Merck's products?

    We believe the proper objective should be that launch prices 
appropriately reflect the true value of the medicine and are not 
distorted by any misaligned incentives in Medicare Part D or any other 
sector. We believe the administration's proposed rebate safe harbor, 
and similar changes in commercial plans, would address the misaligned 
incentives in the marketplace that favor high list prices and high 
rebates in competitive markets. In addition, addressing the misaligned 
incentives for the 340B program would allow for more flexibility in 
list prices.
                              transparency
    Question. In many of your testimonies, you mentioned that the 
current system of pharmacy benefit manager (PBM) back-end rebates do 
not rarely results in a scenario where the PBM passes on savings to 
consumers at the point of sale (POS). The administration recently 
proposed a rule to eliminate the anti-kickback statute safe harbor 
protections for these drug rebates.

    Do you agree that greater transparency should be required to 
understand how manufacturers and PBMs are negotiating prices and 
rebates to ensure that savings are passed down to beneficiaries?

    Answer. Yes. We believe there should be greater transparency of the 
financial arrangements between manufacturers and PBMs. In particular, 
we believe we must change the system to ensure that patients receive 
the benefit of the significant rebates and discounts that manufacturers 
like Merck pay to PBMs and plans. The administration's proposed rule is 
a positive step in that direction.

    Based on our initial assessment of the proposed rule, we believe 
that it will remove misaligned incentives within the system, drive more 
transparency in the system, and most importantly, lower beneficiaries' 
out-of-pocket costs.

    Question. Senator Thune asked if this administration rule would 
lead you to lowering list prices. Both of you answered that you would 
be likely to lower your prices. However, if this rule were finalized 
tomorrow as proposed, would any of your companies be required to lower 
the list price of any of your drugs?

    Answer. Under the proposed rule, there is no requirement to lower 
list prices. However, over time, we expect that our list prices will go 
down if the misaligned incentives across the system are addressed. It 
is also important to note that if the rule is implemented, Medicare 
beneficiaries' out-of-pocket costs will be reduced, independent of any 
lowering of list prices, since their cost-sharing will be based on the 
net price. Nonetheless, we believe the rebate rule will align 
incentives in a way that will restrain list prices.
                                  pbms
    Question. An Axios article from March 7, 2019 highlights the fact 
that, while ``pharmaceutical companies put a lot of the blame for high 
drug prices on pharmacy benefit managers,'' many large pharmaceutical 
companies ``rely on PBMs to manage their own health-care benefits.''

    In your role as an employer, does your company contract with a 
pharmaceutical benefit manager (PBM) to administer the prescription 
drug benefits for your employees and negotiate lower drug costs on your 
behalf?

    For those of you who do use a PBM to help manage the prescription 
drug benefit for your employees, how do you utilize the rebates your 
PBM negotiates to lower health care costs or drug costs for your 
employee plans and what does your company do with that savings? 
Specifically, do the savings go toward lowing premiums?

    For those of you who do use a PBM to help manage the prescription 
drug benefit for your employees, does your PBM offer point-of-sale 
rebates to your employees?

    Answer. Merck offers a generous health care benefit for our 24,000 
U.S. employees. There is no deductible for medications covered under 
our pharmacy benefit, and employees never have to pay more than $50 for 
a retail prescription for a covered medication, and in most cases pay 
less. We contract with a PBM for management of the prescription drug 
benefits for our employees, and the benefit does not offer point-of-
sale rebates to our employees. Merck uses savings generated by the PBM 
on rebates to lower overall costs for employees while ensuring low out-
of-pocket costs.

                                 ______
                                 
             Questions Submitted by Hon. Sheldon Whitehouse
    Question. Please describe any policy changes you support that would 
result in your company lowering the list prices of its drugs.

    Answer. Over time, we expect that our list prices will go down if 
the misaligned incentives across the system are addressed. Nonetheless, 
we believe the rebate rule will align incentives in a way that will 
restrain list prices.

    As we stated when we reduced the list price of several of our 
products in July 2018, we have continued to look for opportunities to 
reduce our list prices. We think the proposed rule would help create 
those opportunities, but it can't happen overnight. All of the players 
in the ecosystem will need to adjust to the new model.

    If the proposed rule is implemented as written, it would only apply 
to our contracts with PBMs and health plans for Medicare Part D and 
Managed Medicaid. If PBMs and health plans maintain the rebate model in 
the commercial market, we would still have commercial contracts based 
on rebates, which would be subject to the existing constraints to 
lowering list price. We also would still need a mechanism to revalue 
drug in the distribution channel in a financially viable manner.

    Question. How much does your company's research and development 
portfolio rely on taxpayer-funded research conducted by the National 
Institutes of Health (NIH)? How many of your company's products are 
based, at least in part, on NIH research, and how many are the result 
of research funded solely by your company?

    Answer. The U.S. leads the world in biomedical research thanks to a 
robust biomedical ecosystem comprised of important and unique 
contributions from the National Institutes of Health (NIH), academic 
institutions, and the biopharmaceutical industry. Historically, the 
NIH's focus has been on basic biomedical science and research 
concerning public health (including in the recent budget funding for 
drug and alcohol abuse prevention, reducing health-care disparities, 
and other important causes). Through this basic research, NIH seeks to 
understand the fundamental biological processes and leverage that 
understanding to determine which processes are involved in the 
development and progression of disease. There is significant basic 
research that in some respects contributes to all new medicines. Most 
of this is considered ``pre-competitive'' since the individual 
contributions are in themselves too small or too broad to lead directly 
to a new therapy, which takes considerable work to invent and develop.

    Merck also conducts basic research. However, where we use 
intellectual property that others have created, we are diligent in 
recognizing and agreeing on terms to use that property (including 
financial compensation), which may include with agencies of the U.S. 
government such as NIH. After this stage of basic research, our 
company's further role is to then engage in the most risky and costly 
part of discovery--to invent something that's never existed in the 
history of the world that will alter the targets that come from basic 
research and unlock treatments and cures for disease. This invention is 
then followed by extensive clinical trial programs to demonstrate 
safety and effectiveness.

    On occasion, we will rely on work by government agencies that is 
more advanced; however, we take the same approach of respecting 
intellectual property rights and agreeing on terms of use of that 
property. For example, Merck, along with Instituto Butantan, has 
licensed certain rights from National Institute of Allergy and 
Infectious Diseases (NIAID), part of NIH, for the development of live 
attenuated tetravalent vaccines (LATV).

    All parts of the ecosystem are needed to continue to lead in 
biomedical research: the portion of NIH's entire $33 billion budget 
that it devoted to biomedical research in 2017 as well as the $70 
billion the biopharmaceutical industry spent in 2017--$10 billion of 
which was spent by Merck--to invent and bring to market new treatments 
and cures.

    Question. In each of the last 5 years, how much has your company 
spent on research and development versus the advertising and marketing 
of your products?

    Answer. In 2018, Merck incurred $9.8 billion in research and 
development costs globally, the vast majority of which was conducted in 
the U.S. Since 2010, Merck has invested nearly $70 billion in R&D to 
create new medicines and vaccines that address the greatest health 
challenges of our time--including antimicrobial resistance, Ebola, HIV, 
and cancer--to save and improve lives around the world. In 2018, Merck 
spent about $2.3 billion in the U.S. on direct marketing and selling 
expenses. This number includes all sales and marketing expenses, 
including creative development of resources and headcount related to 
all marketing and sales activity in the U.S. market.

    For the remaining years, we spent the following:

          In 2017, Merck invested $10.3 billion in R&D and $2.5 
        billion in U.S. marketing and selling expenses.

          In 2016, Merck invested $10.3 billion in R&D and $2.5 
        billion on U.S. marketing and selling expenses.

          In 2015, Merck invested $6.8 billion in R&D and $2.4 billion 
        on U.S. marketing and selling expenses.

          In 2014, Merck invested $7.3 billion in R&D and $2 billion 
        on U.S. marketing and selling expenses.

    Question. During the hearing, you mentioned that your company would 
be likely to lower the list prices of its drugs if the recent proposal 
by the Trump administration to change the current system of rebates was 
extended to the private market.

    If the policy was extended to the private market, how large would 
the list price reductions be relative to the size of the rebates your 
company is currently providing?

    Answer. It is hard to predict an exact amount of list price 
reduction if the rule were implemented as described. However, we 
believe that removing the misaligned incentives from the system should 
result in downward pressure on list prices. It is also important to 
understand that different purchasers receive different levels of 
discounts, based on the access provided for patients. So, there is not 
a uniform ``rebate amount'' that could reduce the list price. Moreover, 
we expect that the robust negotiations that occur today will continue 
in the highly competitive Part D market, and we expect to realize the 
same level of net price that we do today. In fact, we expect that there 
could be additional pricing pressure under the new system, which could 
lead to lower net prices.

    Question. How will this proposal affect how your company sets the 
list prices for new drug products?

    Answer. Merck approaches pricing from the perspective of value. 
This approach looks at the value that a medicine provides through 
multiple lenses with the goal of reflecting its benefit to patients and 
to society, while at the same time paying an appropriate return on 
invested capital to our investors, to ensure that we are able to 
sustain R&D. While each individual situation varies based on factual 
circumstances and market dynamics, generally, we consider:

          Value provided to patients--to what extent does a new 
        medicine or vaccine establish a new standard of care that has 
        the potential to significantly extend and improve patient 
        lives?

          Value provided to health-care systems--to what extent does a 
        new medicine or vaccine reduce the costs associated with 
        hospitalization and other costly complications of disease if 
        not appropriately (or optimally) treated?

          Unmet need--does a new medicine or vaccine address a 
        critically unmet medical need, where few or no treatments 
        exist?

          Access--what is the ability of various customers around the 
        world--including national, regional or local institutional 
        payers, physicians, employers and patients--to pay for our 
        products?

          R&D sustainability--given the long-term risk and cost of 
        capital, can we appropriately compensate our investors to 
        ensure continued investment in the kind of risky and capital-
        intensive research and development that will bring forward 
        medically important breakthroughs?

          Competition--what are the costs of other treatments 
        currently on the market relative to the value provided by 
        Merck's products?

    We do not expect this approach to change based on the Trump 
administration's proposed rule.

    Question. If the proposal is finalized and not extended to the 
private market, will your company make any list price reductions? If 
so, how large would the reductions be relative to the size of the 
rebates your company is currently providing?

    Answer. We expect that the robust negotiations that occur today 
will continue in the highly competitive Part D and commercial markets, 
and we expect to realize the same level of net price that we do today. 
In fact, we expect that there could be additional pricing pressure 
under the new system, which could lead to lower net prices, but 
predicting the size of any such reductions is difficult.

                                 ______
                                 
                Question Submitted by Hon. Maggie Hassan
    Question. In June of 2018, the Medicaid and CHIP Payment and Access 
Commission (MACPAC) unanimously recommended under Recommendation 1.1 in 
their annual report to Congress that Congress remove the statutory 
requirement that manufacturers blend the average manufacturer price 
(AMP) of a brand drug and its authorized generic.\13\
---------------------------------------------------------------------------
    \13\ MACPAC. ``Improving Operations of the Medicaid Drug Rebate 
Program,'' https://www.macpac.gov/wp-content/uploads/2018/06/Improving-
Operations-of-the-Medicaid-Drug-Rebate-Program.pdf.

    This requirement created an unintended loophole. Rather than use 
the price of the authorized generic, drug companies can sell its 
authorized generic to a corporate subsidiary at an artificially lower 
price and use that lower price to bring down the AMP, which in turn 
---------------------------------------------------------------------------
lowers the rebate obligation.

    Does your company engage in this practice? Has your company ever 
engaged in this practice in the past?

    Answer. No. Merck does not engage in the practice of selling 
authorized products to a subsidiary and then blending the pricing data 
for the products. Merck does engage with third parties who act as our 
authorized generic partners. Merck has disclosed the methodology used 
to account for these transactions in AMP to CMS.

                                 ______
                                 
           Questions Submitted by Hon. Catherine Cortez Masto
    Question. As a portion of your revenue, for what percentage of the 
drugs in your portfolio do you offer no rebates? Based on the drugs in 
your pipeline, do you foresee that portion growing? For those drugs is 
your list price equal to your net price?

    Answer. Since Merck's entire product portfolio is covered within at 
least one government program that requires a mandated rebate or 
discount (such as Medicaid, 340B, Federal Supply Schedule), there are 
no Merck products that are not rebated or discounted. Merck also offers 
voluntary rebates or discounts on many of its products. We would expect 
similar rebates and discounts to be paid for our drugs in the pipeline, 
barring fundamental changes in the marketplace.

    Question. Do you invest more in R&D than you generate in US sales 
revenue? Please include specific figures.

    Answer. In 2018, Merck incurred $9.8 billion on research and 
development costs globally, the vast majority of which was conducted in 
the U.S. Since 2010, Merck has invested nearly $70 billion in R&D to 
create new medicines and vaccines that address the greatest health 
challenges of our time--including antimicrobial resistance, Ebola, HIV, 
and cancer--to save and improve lives around the world. In 2018, Merck 
had $18.2 billion in U.S. sales revenue.

    Question. Do you invest more in R&D than you spend on marketing and 
administration? What company functions do you consider to be included 
in administration? Please include specific figures.

    Answer. In 2018, Merck incurred $9.8 billion in research and 
development costs globally, the vast majority of which was conducted in 
the U.S. Since 2010, Merck has invested nearly $70 billion in R&D to 
create new medicines and vaccines that address the greatest health 
challenges of our time--including antimicrobial resistance, Ebola, HIV, 
and cancer--to save and improve lives around the world. In 2018, Merck 
spent about $10.1 billion on marketing, selling, and administration 
globally ($2.6 billion of which is directly attributed to the U.S. 
market). This number includes all sales and marketing expenses, 
including creative development of resources and headcount related to 
all marketing and sales activity, as well as administrative expenses 
associated with business support functions, including information 
technology, human resources, facilities, finance, legal, and others.

    Question. Do you invest more in R&D than you spend on marketing and 
sales? What company functions do you consider to be included in sales? 
Please include specific figures.

    Answer. In 2018, Merck incurred $9.8 billion on research and 
development costs globally, the vast majority of which was conducted in 
the U.S. Since 2010, Merck has invested nearly $70 billion in R&D to 
create new medicines and vaccines that address the greatest health 
challenges of our time--including antimicrobial resistance, Ebola, HIV, 
and cancer--to save and improve lives around the world. In 2018, Merck 
spent about $6.9 billion on direct marketing and selling expenses 
globally ($2.3 billion of which is directly attributable to the U.S. 
market). This number includes all sales and marketing expenses, 
including creative development of resources and headcount related to 
all marketing and sales activity in the U.S. market.

    Question. Why do you advertise for the drugs you manufacture? What 
factors do you consider in choosing which drugs you advertise?

    Answer. Merck believes that direct-to-consumer (DTC) advertising 
can be an important and helpful way to inform patients about diseases 
that may be relevant to them and therapeutic options they may want to 
discuss with their physician. Data demonstrate that DTC can have a 
positive impact on patient health in terms of diagnosis, treatment, and 
adherence to prescribed therapies. We recognize that DTC is one channel 
amongst many to help educate patients. Print materials, telephone, 
websites, and other channels are also used to provide more in-depth 
information to patients. The ultimate decision to prescribe a product 
for any specific patient remains with the physician following 
discussion with their patient.

    Merck adheres to FDA regulations and guidelines governing DTC 
promotion and has a long-standing policy to voluntarily submit new DTC 
broadcast advertising campaigns to FDA for pre-review. Merck also 
follows the PhRMA Guiding Principles for DTC Advertisements About 
Prescription Medicines. We are currently considering what additional 
information we can make available to consumers to ensure that they can 
make informed health care decisions.

                                 ______
                                 
              Prepared Statement of Richard A. Gonzalez, 
           Chairman and Chief Executive Officer, AbbVie Inc.
    I am Richard Gonzalez, and I am the chairman and chief executive 
officer of AbbVie, a company dedicated to developing new innovative 
medicines for some of healthcare's most challenging diseases, such as 
cancer, Alzheimer's, viral infections, and auto-immune diseases. Since 
our inception in 2013, AbbVie has invested approximately $50 billion in 
pursuit of that goal. However, because we are tackling medicine's most 
challenging problems, solutions do not come easily or without 
significant risk. Where we have succeeded, we have been able to provide 
cures for fatal diseases like hepatitis C and significantly alter the 
disease progression for certain cancers, lessening the burden of 
illness on patients and the health-care system. This is what the 30,000 
employees of AbbVie are dedicated to doing.

    We agree that access to lifesaving medicines is a critical issue 
and we look forward to sharing our perspectives with you. There is no 
one solution to this complex issue, but AbbVie is open to working with 
the committee on how we can commit our resources to better partner in 
your efforts to address pharmaceutical pricing and access. AbbVie and 
the rest of our industry must play a role in solving these issues and 
be prepared to work together with the insurance industry, the 
administration and you to find a better path forward for American 
patients.

    My remarks today will focus on one aspect of this inquiry--the 
Medicare Part D benefit design, which even after pharmaceutical list 
prices are lowered, still contributes to making innovative therapies 
cost-prohibitive for Medicare patients. In general, the Medicare Part D 
program has worked well. Its market-based structure and utilization of 
formularies encourages competitive price discounts that have yielded 
significant savings to the government since the Part D benefit was 
established in 2006. However, despite these cost savings, Part D 
patients' out-of-pocket costs have significantly increased. Some would 
blame that solely on high drug prices, and we agree that price should 
certainly be part of the discussion. But it's also important to 
acknowledge that science has enabled us to advance the standard of care 
far beyond what was possible when the Part D benefit was designed.

    Many of today's specialty medicines offer major advances in 
treating or curing serious chronic or life-threatening conditions and 
save significant amounts of money for the health-care system by 
decreasing overall health-care costs, yet these therapies are also 
costly. Due to the structure of the Part D benefit design, patients are 
charged out-of-pocket costs on a medicine's list price which does not 
reflect the 
market-based rebates that Medicare receives. We are encouraged by the 
proposed rule that would reflect manufacturer discounts in patients' 
Part D out-of-pocket payments. This is an important step in the right 
direction, but we believe more must still be done to help Part D 
patients.

    Let me give you a recent real-world example that demonstrates the 
challenge with the current Part D benefit design and why the focus 
solely on list prices does not fully address the access challenges. An 
uncured hepatitis C infection leads to downstream medical costs for 
surgery, chemotherapy, and radiation for patients who progress to 
needing a liver transplant or having liver cancer. Today we can cure 
hepatitis C with drugs. This cure is highly cost-effective for the 
overall health-care system.

    In 2017, AbbVie launched Mavyret, a highly effective cure for HCV. 
At the time, the list prices for the competitive alternatives were as 
high as $94,500 for their most commonly prescribed treatment duration. 
We launched Mavyret at a list price that is 72 percent lower. But even 
though we cut the list price of an HCV cure for most patients by 72 
percent, Medicare Part D patients' out-of-pocket obligations are still 
too high for many patients to access this medicine.

    We believe it is important that discussions about access and 
affordability include a focus on how to alleviate Medicare Part D out-
of-pocket burdens above and beyond just lowering list prices. We are 
prepared to step up and discuss how companies like ours can shoulder 
more of the burden of a patient's out-of-pocket expenses, as we do in 
other areas covered by commercial insurance. Additionally, we believe 
the discussion should also include the possibility of Medicare Part D 
beneficiaries being able to purchase insurance (as they do in other 
parts of the Medicare program) to cover more of their out-of-pocket 
expenses.

    We believe AbbVie, the rest of the pharmaceutical industry and 
insurance providers should come together with the administration and 
you to work toward solutions that make life-changing medicines more 
affordable to Part D beneficiaries. I can assure you AbbVie is 
committed to doing its part, and we look forward to working with you.

                                 ______
                                 
     Questions Submitted for the Record to Richard A. Gonzalez \1\
---------------------------------------------------------------------------
    \1\ Please note that these responses were prepared by and are from 
AbbVie Inc.
---------------------------------------------------------------------------
               Questions Submitted by Hon. Chuck Grassley
    Question. The Department of Health and Human Services' proposed 
rule, ``Fraud and Abuse; Removal of Safe Harbor Protection for Rebates 
Involving Prescription Pharmaceuticals and Creation of New Safe Harbor 
Protection for Certain Point-of-Sale Reductions in Price on 
Prescription Pharmaceuticals and Certain Pharmacy Benefit Manager 
Service Fees,'' envisions that drug manufacturers will offer up-front 
discounts rather than the back-end rebates that are now commonly 
provided. Some observers argue that a 1996 court case called into 
question whether manufacturers could offer up-front discounts, 
resulting in today's rebate-based system. I've heard differing opinions 
as to whether the issues related to the initial court case are still 
relevant. If the HHS proposed rule is finalized, can you assure the 
Committee that your company will offer up-front discounts? If not, why?

    Please describe how you expect your company to respond to the HHS 
proposed rule to eliminate safe harbor protection for back-end rebates 
in Medicare Part D that is referenced above if it is finalized. 
Assuming you are confident that antitrust laws do not prevent your 
company from offering up-front discounts, specifically, do you envision 
that your company lowers the list price of a drug to the current after-
rebate net price, offer discounts equal to the current rebate amount, 
or a combination of both?

    Answer. There has been significant discussion over the past several 
months about proposals to eliminate rebates from Medicare Part D, 
Medicaid, and the commercial market culminating in the administration's 
publication of a proposed rule to ``expressly exclud[e] from safe 
harbor protection under the Anti-Kickback Statute (AKS) rebates on 
prescription drugs paid by manufacturers to pharmacy benefit managers 
(PBMs), Part D plans, and Medicaid managed care organizations. The 
proposal would create a new safe harbor protecting discounts offered to 
patients at the pharmacy counter. Finally, the proposal would create 
new safe harbor protection for fixed fee services arrangements between 
manufacturers and PBMs.''

    AbbVie is encouraged by the goals of the proposed rule to ensure 
manufacturer discounts are reflected in and reduce patient cost sharing 
under Part D. While we believe the rule is an important step in the 
right direction, we also believe more should be done to help reduce the 
out-of-pocket cost burden on Medicare Part D patients.

    As for what the elimination of rebates might mean to the overall 
health-care system or pharmaceutical companies, it is premature to 
comment on these items until the administration's rule is finalized, 
implementation timelines are solidified, and there are specific details 
regarding how a new system without rebates will be structured and 
function.

    Question. To what extent are the back-end rebates your company 
currently offers contingent on the amount of market share realized for 
your drugs as a result of Part D plan formulary placement and other 
techniques?

    Answer. AbbVie does not have market-share based arrangements.

    Question. Please provide a breakdown of percentage of sales that go 
to each payer (including Medicare, Medicaid, private pay, other) and a 
similar percentage by volume of the total number of each drug compared 
to total volume. Please provide this data for the most recent year 
available.

    Answer. In 2018, on a U.S. dollars basis approximately 68 percent 
of AbbVie's U.S. net sales were to commercial payers and approximately 
32 percent were to government payers. AbbVie does not maintain this 
information on a volume basis across all products. For Humira, AbbVie's 
top product for sales, on a volume basis in the U.S. approximately 68 
percent of Humira sales were to commercial payers and approximately 32 
percent were to government payers. But on a U.S. dollars basis, 
approximately 83 percent of Humira sales were to commercial payers and 
only approximately 17 percent were to government payers.

    Question. Do your companies hire consultants or lobbyists to 
promote products at State Medicaid Pharmacy and Therapeutics 
Committees? To whom do you disclose advocacy activities surrounding 
State Medicaid programs, if at all?

    Answer. AbbVie does not hire consultants or lobbyists to promote 
products at State Medicaid Pharmacy and Therapeutics Committees. We 
adhere to individual State's laws and regulations with respect to 
advocacy disclosures.

    Question. Please describe how the costs of patient assistance 
programs are accounted for within your company's financial statements. 
Please also describe the types of market information, such as 
prescribing and use patterns, that your company collects from different 
types of patient assistance programs and patient hub services.

    Answer. The AbbVie Patient Assistance Program, which provides free 
drug to eligible individuals, falls under the administration portion of 
SG&A. AbbVie's commercial co-pay assistance costs are deducted from 
gross sales.

    The information that AbbVie collects through its patient support 
services varies by products but may include demographic information, 
diagnosis codes and prescription information, insurance information, 
and claim information. AbbVie collects a more limited set of this data 
through its Patient Assistance Program in order to assess patients for 
eligibility and distribute medication to patients.

    Question. Please provide a list of all contributions since January 
1, 2014, that your company has made to any tax exempt organizations 
working on issues related to drugs within your product lines, including 
but not limited to patient groups, disease awareness groups, medical or 
professional societies, universities or hospitals, industry 
associations or leagues. for each contribution, please provide the name 
of the organization that received the donation, the date the donation 
was made, the amount of the donation, and a description of the purpose 
of the contribution (i.e., was the contribution for the general fund, a 
specific purpose to a specific program, or continuing medical 
education). Please also note whether the contribution was unrestricted 
or restricted; if it was restricted, please explain all restrictions. 
Finally, if your company maintains a foundation or other separate 
charitable arm, please provide the name of all such entities, and list 
all donations made from that entity or entities.

    Answer. Attached as Exhibit 1 to this response is a list of all 
contributions AbbVie has made in the following categories from January 
1, 2014 through December 31, 2018: (1) charitable donations to non-
profit organizations; (2) donations for patient education and disease 
state diagnosis, treatment, and awareness; (3) educational grants; (4) 
fellowships and scholarships; and (5) sponsorships of non-profit 
organizations' events.

    The AbbVie Foundation is a separate non-profit entity that makes 
charitable donations and grants. Attached as Exhibit 2 is a list of all 
charitable donations and grants made by The AbbVie Foundation from 
January 1, 2014 through December 31, 2018.

    Question. Pay-for-delay agreements cost consumers and taxpayers 
billions in higher drug costs every year. The FTC has gone after drug 
companies that enter into these settlements where the brand pays the 
generic company to keep its lower cost alternative off the market. I'm 
the lead Republican sponsor of S. 64, the ``Preserve Access to 
Affordable Generics and Biosimilars Act,'' which would help put an end 
to these deals.

    Do you agree that these pay-off agreements keep drug costs high for 
patients because they delay competition?

    Has your company ever entered into these kinds of settlements with 
a generic company?

    Answer. ``Pay-for-delay'' is not a self-defining phrase. With 
respect to the term ``pay,'' patent litigation settlements, like all 
litigation settlements, involve compromise in which both sides believe 
they are getting value from the resolution. There is no definition 
explaining the circumstances under which that value would implicate the 
term ``pay'' in ``pay-for-delay'' for purposes of these questions. And 
with respect to ``delay'' virtually all patent settlements provide for 
the generic competitor to enter the market before the expiration of the 
patent at issue. So if the alternative resolution of a patent lawsuit 
would be the innovator company continuing to enforce its patent until 
expiration, then such a settlement, no matter what value is exchanged, 
would actually accelerate competition, not delay it.

    Question. Do you support the pay-for-delay bill?

    Answer. AbbVie supports the goals of the Preserve Access to 
Affordable Generics and Biosimilars Act and would likely support the 
bill upon clarification that enforcement only applies to agreements 
after the date of enactment.
                           rebate traps/walls
    Question. I'm increasingly concerned about the effect of so-called 
``rebate traps'' or ``rebate walls'' on patients' access to quality, 
lower-cost medicine. I understand there is ongoing litigation 
challenging these practices as anti-competitive.

    Does your company engage in the bundling of rebates over multiple 
products? If so, why? And what benefit does the consumer gain from 
that?

    Does your company view these practices as anticompetitive or 
harmful to patients' access to quality, lower cost medicine?

    Answer. Rebates are a form of price competition that results from 
the aggressive negotiations that occur between health plans (and their 
representative PBMs) and pharmaceutical companies to provide patients 
with access to medicines and treatments that can best help patients 
manage their medical conditions.

    Question. If a policy were adopted to eliminate rebates, or to 
require that rebate savings be passed on to the consumer, would that in 
and of itself solve the issue of rebate ``traps'' and ``walls''? And 
would consumers benefit from such a policy?

    Answer. There has been significant discussion over the past several 
months about proposals to eliminate rebates from Medicare Part D, 
Medicaid, and the commercial market culminating in the administration's 
publication of a proposed rule to ``expressly exclud[e] from safe 
harbor protection under the Anti-Kickback Statute (AKS) rebates on 
prescription drugs paid by manufacturers to pharmacy benefit managers 
(PBMs), Part D plans, and Medicaid managed care organizations. The 
proposal would create a new safe harbor protecting discounts offered to 
patients at the pharmacy counter. Finally, the proposal would create 
new safe harbor protection for fixed fee services arrangements between 
manufacturers and PBMs.''

    AbbVie is encouraged by the goals of the proposed rule to ensure 
manufacturer discounts are reflected in and reduce patient cost sharing 
under Part D. While we believe the rule is an important step in the 
right direction, we also believe more should be done to help reduce the 
out-of-pocket cost burden on Medicare Part D patients.

    As for what the elimination of rebates might mean to the overall 
health care system or pharmaceutical companies, it is premature to 
comment on these items until the administration's rule is finalized, 
implementation timelines are solidified, and there are specific details 
regarding how a new system without rebates will be structured and 
function.
                              drug pricing
    Question. When setting the list price of a drug, does your company 
consider regulatory costs or compliance? If so, how specifically do 
those factors affect the list price of a drug? Please provide at least 
one specific example, if applicable, from your current product 
portfolio.

    Answer. AbbVie does not consider regulatory costs or compliance 
when considering the list price of a medicine.

    Question. When setting the list price of a drug, does your company 
consider the risk of liability or litigation? If so, how specifically 
do those factors affect the list price of a drug? Please provide at 
least one specific example, if applicable, from your current product 
portfolio.

    Answer. AbbVie does not consider the risk of liability or 
litigation when considering the list price of a medicine.

                                 ______
                                 
                Questions Submitted by Hon. Pat Roberts
    Question. What role do you see value-based arrangements (VBAs) 
playing in the effort to reduce prescription drug costs? What potential 
do these arrangements have to find the ``sweet spot'' between 
controlling costs to patients and encouraging innovation of new drugs?

    How can VBAs help lower what patients pay out-of-pocket?

    Can Congress do more to allow for and encourage the use of VBAs?

    Answer. Value-based arrangements can be an effective and market-
based solution to managing overall health-care costs when driven by 
patient outcomes. Studies have found that 38 percent of payers with 
outcomes-based contracts experience improved patient outcomes and 33 
percent experience plan health-care cost savings. Additionally, plans 
with outcomes-based contracts have been found to have a 28 percent 
lower patient co-payment. All of these factors work towards moving 
payment for prescription medicines away from volume-based approaches to 
value-based models in a manner that appropriately balances patient 
access with the appropriate use of medications to lower overall health-
care costs.

    At AbbVie, we believe all our products provide value to patients 
and the larger health-care system and are interested in the 
possibilities that could arise through value-based contracting. To 
further foster value-based arrangements, we support the reforms 
included in the Patient Affordability, Value and Efficiency (PAVE) Act, 
introduced by Senators Cassidy (R-LA) and Warner (D-VA).

                                 ______
                                 
                Questions Submitted by Hon. John Cornyn
    Question. We continue to hear that rebates negotiated off of the 
list price of a drug are both good and bad.

    Pharmacy benefit managers and plans have argued that rebates are 
used to lower premiums across the board and that it is the best way to 
seek a price concession on otherwise expensive drugs.

    Your industry argues that these payers are insisting on higher 
rebates that can only be achieved by raising list prices.

    But patients often lose under this system, with out of pocket costs 
being tied to list price. Insulin patients appear to be routinely 
impacted by this perversity in the system.

    Please explain to the committee how your company would reduce list 
prices if rebates were no longer a part of the equation?

    What assurance can you provide that you would in fact lower your 
prices?

    Answer. There has been significant discussion over the past several 
months about proposals to eliminate rebates from Medicare Part D, 
Medicaid, and the commercial market culminating in the administration's 
publication of a proposed rule to ``expressly exclud[e] from safe 
harbor protection under the Anti-Kickback Statute (AKS) rebates on 
prescription drugs paid by manufacturers to pharmacy benefit managers 
(PBMs), Part D plans, and Medicaid managed care organizations. The 
proposal would create a new safe harbor protecting discounts offered to 
patients at the pharmacy counter. Finally, the proposal would create 
new safe harbor protection for fixed fee services arrangements between 
manufacturers and PBMs.''

    AbbVie is encouraged by the goals of the proposed rule to ensure 
manufacturer discounts are reflected in and reduce patient cost sharing 
under Part D. While we believe the rule is an important step in the 
right direction, we also believe more should be done to help reduce the 
out-of-pocket cost burden on Medicare Part D patients.

    As for what the elimination of rebates might mean to the overall 
health care system or pharmaceutical companies, it is premature to 
comment on these items until the administration's rule is finalized, 
implementation timelines are solidified, and there are specific details 
regarding how a new system without rebates will be structured and 
function.

    Question. What actions should be taken to ensure that patients are 
actually seeing the benefits of lower out-of-pocket costs?

    Answer. Providing discounts to the patient at the point of sale is 
an effective way of ensuring that patients can see lower out-of-pocket 
costs. However, this is just the start. AbbVie believes that more must 
be done.

    The Medicare Part D benefit design contributes to making innovative 
therapies cost-prohibitive for Medicare patients because patients are 
charged out-of-pocket costs based on a medicine's list price, which 
does not reflect the rebates that Medicare receives.

    AbbVie believes it is important to alleviate the burdens that 
patients face due to Medicare Part D out-of-pocket costs. AbbVie 
supports solutions like a patient out-of-pocket cap in Part D and 
smoothing patient out-of-pocket payments over a full year, so patients 
have some predictability with respect to their out-of-pocket costs.

    In addition, AbbVie is prepared to step up and discuss how 
companies like ours can shoulder more of the burden of a patient's out-
of-pocket expenses.

    As policymakers consider the impact of addressing out-of-pocket 
costs in Medicare Part D, questions may arise around whether it will 
lead to unnecessary utilization and wasteful spending. for specialty 
medicines, increased utilization should not be misunderstood as 
unnecessary or wasteful. Part D plans have tools, like step therapy 
requirements for patients to first try lower cost alternatives before a 
specialty medicine would be covered and prior authorization 
requirements before a specialty medicine would be covered, to manage 
the utilization of the majority of higher cost specialty medicines. 
These tools ensure patients try a less costly medication first and have 
met the clinical criteria for taking the specialty drug prescribed and 
serve the function that an out-of-pocket cost obligation on patients 
might serve to prevent unnecessary use.

    Question. If rebates are driving high list prices for drugs as drug 
manufacturers' claim, why do you think that Part B drugs, which have no 
PBM rebates, are also seeing significant price increases? Whose fault 
is that?

    Answer. Manufacturers do offer rebates on Part B products in the 
commercial market. Those rebates are included in the calculation of the 
Part B Average Sales Price (ASP) and are therefore reflected in the 
price Medicare pays for Part B drugs. AbbVie does, however, recognize 
that increased competition in Part B could lead to additional savings 
and welcomes the opportunity to engage in policy discussions that seek 
to increase competition in Part B.

                                 ______
                                 
               Question Submitted by Hon. Michael B. Enzi
    Question. The Food and Drug Administration's drug review process is 
known to many as the ``gold standard'' for evaluating medical products. 
I've long thought that it is critical that we maintain public 
confidence in their ability to ensure that drugs are safe and 
effective. There is a perception among some, however, that biosimilars 
might not be as safe as their reference products. That perception can 
undermine patient and provider confidence. Do you believe that when FDA 
approves a biosimilar, providers can be confident that it is safe and 
effective?

    Answer. Consistent with the US regulatory scheme for biosimilars, 
we recognize that FDA-approved biosimilars are highly similar to the 
reference product with no clinically meaningful differences.

    Unlike small molecule generics, however, biosimilars do not contain 
the identical active ingredient as their reference products and 
biosimilars are not substitutable at the pharmacy for the reference 
drug absent an FDA designation of interchangeability. As FDA has 
acknowledged, multiple exposures to slightly different biologics can 
prime the immune system to recognize subtle differences in structural 
features between products, triggering or increasing the overall immune 
response. Consequently, a finding of interchangeability must be 
supported by additional data demonstrating that the biosimilar is 
``expected to produce the same clinical result in any given patient,'' 
and that there is no risk to patients associated with alternating or 
switching between the biosimilar and the reference product. There is no 
requirement that two biosimilars found to be interchangeable with a 
single reference product must show that it is safe and effective to 
switch between the two interchangeable biosimilars, even though in 
practice this is likely to happen in the marketplace if biosimilars are 
treated like generic drugs. Different biosimilar products each found 
interchangeable with a single reference product will have subtle 
structural differences from each other. Indeed, there may be more 
structural differences--or different types of structural differences--
between the two biosimilar products than between either biosimilar and 
the reference product. As such, without clinical data assessing the 
effects of switching between two biosimilars of the same reference, 
there is no evidence to scientifically justify interchangeability or 
automatic substitution between them. AbbVie has raised this concern 
with FDA at a 2018 Part 15 Hearing held by the agency on the subject of 
biosimilarity and interchangeability.

    These fundamental distinctions between small molecule and biologic 
medicine regulation should not change the perception that FDA-approved 
biosimilars are safe and effective, but they are central to any 
understanding of the biologics market and the appropriate use of these 
complex products.

                                 ______
                                 
                 Questions Submitted by Hon. Todd Young
         re-evaluating business strategies in foreign countries
    Question. Since taking office, President Trump has made reducing 
drug prices one of his highest priorities--and has repeatedly spoken 
about his frustration with the U.S. subsidizing the costs of 
pharmaceuticals for the rest of the world. He has gone so far as to 
issue proposals, like the International Pricing Index (IPI) Model, in 
an attempt to bring down prescription drug prices.

    With the increased scrutiny of the industry and of the drug supply 
chain as a whole in the United States, have any of your companies re-
evaluated your business strategy in foreign countries?

    If not, then why?

    If a proposal, like IPI, were implemented, would it force your 
companies to potentially ``walk away from the negotiating table when 
other countries demand low prices subsidized by America's seniors,'' as 
HHS Senior Advisor for Drug Pricing Reform John O'Brien has said?

    Answer. The focus on U.S. versus ex-U.S. prices for pharmaceuticals 
creates an erroneous impression that medicines are the major driver of 
U.S. health care cost growth--ignoring that medicines account for a 
small share of overall health spending. Many countries impose price 
controls and restrict access to medicines in order to contain costs. 
That is not the system we have here in the United States; nor should it 
be. The U.S. fosters innovation and leads the world in drug discovery 
and development with PhRMA members conducting nearly 80 percent of 
their R&D in the United States. Importing or referencing price controls 
used in other countries in the U.S. would challenge the innovation 
model in a country the size of the U.S.

    The U.S. relies on its competitive marketplace to manage costs, 
while encouraging the development of new therapies. Because of the 
ecosystem that exists in the U.S., patients enjoy access to innovative 
medicines far earlier than patients in countries with centralized price 
controls. Furthermore, most crosscountry comparisons focus solely on 
the list prices of medicines and exclude from calculations the steep 
discounts that are required in U.S. public programs such as Medicaid 
and the rebates negotiated by insurers and pharmacy benefit managers in 
Medicare Part D and the commercial market. In addition, these 
comparisons often only include the list prices of brand-name medicines 
even when lower-cost generic versions are available and widely used.

    Instead of referencing price, AbbVie recommends policymakers focus 
on reforms that address foreign freeloading in new trade agreements or 
increasing enforcement of current agreements. We support enhancements 
to trade agreements to balance share of investment costs. The United 
States-Mexico-Canada Agreement (USMCA), while not yet implemented, 
contains improvements in intellectual property protections as well as 
provisions requiring transparency in pricing and reimbursement 
mechanisms. These elements are critical to ensuring trading partners 
like Mexico and Canada appropriately value innovation, allowing 
innovative biopharmaceutical companies to continue bringing new 
medicines to the market.

    Question. What are some of your ideas on how we can ensure 
Americans aren't shouldering the full cost of pharmaceuticals?

    Answer. Providing discounts to the patient at the point of sale is 
an effective way of ensuring that patients can see lower out-of-pocket 
costs. However, this is just the start. AbbVie believes that more must 
be done.

    The Medicare Part D benefit design contributes to making innovative 
therapies cost-prohibitive for Medicare patients because patients are 
charged out-of-pocket costs based on a medicine's list price, which 
does not reflect the rebates that Medicare receives.

    AbbVie believes it is important to alleviate the burdens that 
patients face due to Medicare Part D out-of-pocket costs. AbbVie 
supports solutions like a patient out-of-pocket cap in Part D and 
smoothing patient out-of-pocket payments over a full year, so patients 
have some predictability with respect to their out-of-pocket costs.

    In addition, AbbVie is prepared to step up and discuss how 
companies like ours can shoulder more of the burden of a patient's out-
of-pocket expenses.

    As policymakers consider the impact of addressing out-of-pocket 
costs in Medicare Part D, questions may arise around whether it will 
lead to unnecessary utilization and wasteful spending. for specialty 
medicines, increased utilization should not be misunderstood as 
unnecessary or wasteful. Part D plans have tools, like step therapy 
requirements for patients to first try lower cost alternatives before a 
specialty medicine would be covered and prior authorization 
requirements before a specialty medicine would be covered, to manage 
the utilization of the majority of higher cost specialty medicines. 
These tools ensure patients try a less costly medication first and have 
met the clinical criteria for taking the specialty drug prescribed and 
serve the function that an out-of-pocket cost obligation on patients 
might serve to prevent unnecessary use.

              foreign countries' pricing and reimbursement
    Question. President Trump and Secretary Azar have both repeatedly 
described their frustrations with ``foreign freeloading'' of U.S. drugs 
in the last year.

    ``When foreign governments extort unreasonably low prices from U.S. 
drug makers, Americans have to pay more to subsidize the enormous cost 
of research and development. . . . It's unfair and it's ridiculous, and 
it's not going to happen any longer.''

    Do you agree that because of foreign countries' pricing and 
reimbursement systems, U.S. patients and innovators are shouldering the 
burden for financing medical advances?

    How do foreign countries' pricing and reimbursement systems affect 
our prescription drug costs?

    Are foreign governments taking note of the concerns being raised by 
the Trump administration and have they responded in any way?

    Has there been any noticeable change in any of our trade agreements 
since these concerns have been raised by the Trump Administration?

    Answer. The focus on U.S. versus ex-U.S. prices for pharmaceuticals 
creates an erroneous impression that medicines are the major driver of 
U.S. health-care cost growth--ignoring that medicines account for a 
small share of overall health spending. Many countries impose price 
controls and restrict access to medicines in order to contain costs. 
That is not the system we have here in the United States; nor should it 
be. The U.S. fosters innovation and leads the world in drug discovery 
and development with PhRMA members conducting nearly 80% of their R&D 
in the United States. Importing or referencing price controls used in 
other countries in the U.S. would challenge the innovation model in a 
country the size of the U.S.

    The U.S. relies on its competitive marketplace to manage costs, 
while encouraging the development of new therapies. Because of the 
ecosystem that exists in the U.S., patients enjoy access to innovative 
medicines far earlier than patients in countries with centralized price 
controls. Furthermore, most crosscountry comparisons focus solely on 
the list prices of medicines and exclude from calculations the steep 
discounts that are required in U.S. public programs such as Medicaid 
and the rebates negotiated by insurers and pharmacy benefit managers in 
Medicare Part D and the commercial market. In addition, these 
comparisons often only include the list prices of brand-name medicines 
even when lower-cost generic versions are available and widely used.

    Instead of referencing price, AbbVie recommends policymakers focus 
on reforms that address foreign freeloading in new trade agreements or 
increasing enforcement of current agreements. We support enhancements 
to trade agreements to balance share of investment costs. The United 
States-Mexico-Canada Agreement (USMCA), while not yet implemented, 
contains improvements in intellectual property protections as well as 
provisions requiring transparency in pricing and reimbursement 
mechanisms. These elements are critical to ensuring trading partners 
like Mexico and Canada appropriately value innovation, allowing 
innovative biopharmaceutical companies to continue bringing new 
medicines to the market.
                  medicaid closed formulary proposals
    Question. In an attempt to bring down drug costs, various states 
have been exploring whether to exclude certain drugs from its Medicaid 
program. for example, the state of Massachusetts' recently asked CMS 
for permission to create a closed formulary where the state Medicaid 
program would pick at least one drug per therapeutic class. CMS denied 
their waiver request citing violation of federal law, but this proposal 
does bring up important questions on how to contain drug prices in 
state Medicaid programs.

    If the principles of the Medicare Part D program--including the 
necessary patient protections--were applied to state Medicaid programs, 
do you think it lower drugs costs while ensuring access to patients?

    Answer. Medicaid patients currently have broad access to medicines 
with nominal co-pay amounts in exchange for steep mandatory rebates 
provided by manufacturers. While the question does not specify what 
``principles of the Medicare Part D program'' or ``necessary patient 
protections'' are proposed to be applied to State Medicaid programs, 
depending on the specific details that might be proposed, exclusionary 
formularies could upset this broad patient access in Medicaid without 
achieving corresponding savings over the already-existing steep 
mandatory rebates.
                        medicaid ``best price''
    Question. In the Trump administration's Blueprint, they suggested 
that because drug manufactures have to give Medicaid the ``best price'' 
on drugs, there is no incentive to offer deeper discounts to other 
payers--both government and commercial--than what is already offered 
under the Medicaid Drug Rebate Program.

    Does the Medicaid ``best price'' requirement encourage 
manufacturers to increase initial prices?

    What, if any, changes would you suggest we make to the program?

    Answer. AbbVie has not found that best price requirements have 
created incentives in the system to increase initial prices.

                        outcomes-based contracts
    Question. In almost all of your testimonies, you highlight your 
support of outcomes-based contracts and how we need to be shifting our 
system toward that approach.

    How will these contracts lower drug costs for patients in both the 
near term and long-term?

    How will they lower overall health-care costs for our Federal 
programs?

    What have the preliminary results looked like so far?

    Answer. Value-based arrangements can be an effective and market-
based solution to managing overall health-care costs when driven by 
patient outcomes. Studies have found that 38 percent of payers with 
outcomes-based contracts experience improved patient outcomes and 33 
percent experience plan health-care cost savings. Additionally, plans 
with outcomes-based contracts have been found to have a 28 percent 
lower patient co-payment. All of these factors work towards moving 
payment for prescription medicines away from volume-based approaches to 
value-based models in a manner that appropriately balances patient 
access with the appropriate use of medications to lower overall health-
care costs.

    At AbbVie, we believe all our products provide value to patients 
and the larger health care system and are interested in the 
possibilities that could arise through value-based contracting. To 
further foster value-based arrangements, we support the reforms 
included in the Patient Affordability, Value and Efficiency (PAVE) Act, 
introduced by Senators Cassidy (R-LA) and Warner (D-VA).
                       transparency/point of sale
    Question. In almost all of your testimonies, you express your 
support for the Trump Administration's proposal to allow manufacturers 
to provide PBMs up-front discounts that are passed onto patients at the 
point-of-sale.

    Do you feel like this proposal will make the transactions within 
the drug supply chain more transparent?

    If so, would this transparency bring down drug costs--overall and 
for specialty drugs?

    Answer. There has been significant discussion over the past several 
months about proposals to eliminate rebates from Medicare Part D, 
Medicaid, and the commercial market culminating in the administration's 
publication of a proposed rule to ``expressly exclud[e] from safe 
harbor protection under the Anti-Kickback Statute (AKS) rebates on 
prescription drugs paid by manufacturers to pharmacy benefit managers 
(PBMs), Part D plans, and Medicaid managed care organizations. The 
proposal would create a new safe harbor protecting discounts offered to 
patients at the pharmacy counter. Finally, the proposal would create 
new safe harbor protection for fixed fee services arrangements between 
manufacturers and PBMs.''

    AbbVie is encouraged by the goals of the proposed rule to ensure 
manufacturer discounts are reflected in and reduce patient cost sharing 
under Part D. While we believe the rule is an important step in the 
right direction, we also believe more should be done to help reduce the 
out-of-pocket cost burden on Medicare Part D patients.

    As for what the elimination of rebates might mean to the overall 
health care system or pharmaceutical companies, it is premature to 
comment on these items until the Administration's rule is finalized, 
implementation timelines are solidified and there are specific details 
regarding how a new system without rebates will be structured and 
function.
         the relationship between wholesalers and manufacturers
    Question. When talking about the pharmaceutical supply chain, a lot 
of focus has been placed on the Pharmacy Benefit Manager. But there's 
another side of the equation that I'd like to ask about.

    How do wholesalers negotiate pricing with manufacturers?

    What impact does this have on drug costs?

    What incentives or disincentives do they have to contain price 
increases?

    Answer. Wholesalers provide efficiencies in the distribution of 
products for manufacturers, pharmacies and providers. They track supply 
needs and maintain inventory levels consistent with patient need. They 
also provide manufacturers with data and information related to both 
historical purchasing patterns and projected future need, allowing 
manufacturers to more accurately predict future supply needed in the 
market to determine production needs. Wholesalers are also a ``one-stop 
shop'' for sourcing medications and in some cases provide payer 
contracting efficiencies through their Pharmacy Services Administrative 
Organizations. This allows pharmacies to gain access to payer networks 
efficiently, without negotiating with individual payers.

    Manufacturers pay bona fide fees to wholesalers cover the costs of 
the services described above.

                                 ______
                                 
                 Questions Submitted by Hon. Ron Wyden
                          proposed rebate rule
    Question. As has been done in many other settings, drug 
manufacturers said during the hearing that one reason list prices for 
drugs are high is that pharmaceutical benefit managers (PBMs) demand 
larger and larger rebates in order for the drug to receive favorable 
placement on a formulary. You and your colleagues who testified during 
the hearing stated if the Administration's proposal on changes to the 
anti-kickback safe harbor for pharmaceutical rebates took effect, your 
company would likely lower list price.

    Like many Oregonians, I am skeptical drug manufacturers would 
voluntarily lower their prices. Therefore, would you support 
legislation that would (1) make similar changes the administration has 
put forward related to Part D and Medicaid managed care, (2) change the 
rebate system in a similar way to the proposal for the commercial 
market, and (3) require drug makers to lower the list price of their 
drugs equal to the amount of rebates provided today?

    Answer. There has been significant discussion over the past several 
months about proposals to eliminate rebates from Medicare Part D, 
Medicaid, and the commercial market culminating in the administration's 
publication of a proposed rule to ``expressly exclud[e] from safe 
harbor protection under the Anti-Kickback Statute (AKS) rebates on 
prescription drugs paid by manufacturers to pharmacy benefit managers 
(PBMs), Part D plans, and Medicaid managed care organizations. The 
proposal would create a new safe harbor protecting discounts offered to 
patients at the pharmacy counter. Finally, the proposal would create 
new safe harbor protection for fixed fee services arrangements between 
manufacturers and PBMs.''

    AbbVie is encouraged by the goals of the proposed rule to ensure 
manufacturer discounts are reflected in and reduce patient cost sharing 
under Part D. While we believe the rule is an important step in the 
right direction, we also believe more should be done to help reduce the 
out-of-pocket cost burden on Medicare Part D patients.

    As for what the elimination of rebates might mean to the overall 
health-care system or pharmaceutical companies, it is premature to 
comment on these items until the administration's rule is finalized, 
implementation timelines are solidified, and there are specific details 
regarding how a new system without rebates will be structured and 
function.
                      medicaid drug rebate program
    Question. The Medicaid Drug Rebate Program (MDRP) requires 
manufacturers to provide a basic rebate and an additional inflationary 
rebate for both brand and generic drugs. The inflationary rebate is an 
increasingly substantial part of total rebates due in large part to 
large increases in drug prices that exceed inflation. Under current 
law, this inflationary rebate is capped at 100 percent of Average 
Manufacturer Price (AMP). This is the case even when manufacturers 
continue to raise their prices well above inflation.

    Please provide a list of all of your pharmaceutical products that 
have reached the Medicaid AMP rebate cap in any of the 20 quarters from 
January 1, 2014 through December 31, 2018.

    For each drug listed in response to question 1, please also provide 
a list of which quarters and years each drug hit the cap.

    Answer.

------------------------------------------------------------------------
       PRODUCT NAME               NDC 11          QTR/YEAR of AMP CAPs
------------------------------------------------------------------------
Androgel 1%, 2.5 G Unit        00051-8425-30   Q1 2015
 Dose, 30'S
------------------------------------------------------------------------
Androgel 1%, 5.0 G Unit        00051-8450-30   Q1 2015
 Dose, 30'S
------------------------------------------------------------------------
Androgel 1.62% 2.5Gm Unit      00051-8462-30   Q2 2017, Q1 2018-Q3 2018
 Dose
------------------------------------------------------------------------
Androgel 1.62% 1.25Gm Unit     00051-8462-31   Q2 2017, Q1 2018-Q3 2018
 Dose
------------------------------------------------------------------------
Androgel 1.62% Pump            00051-8462-33   Q2 2017, Q1 2018-Q3 2018
------------------------------------------------------------------------
Biaxin, Filmtab Tablets,       00074-2586-60   Q3 2016-Q4 2016
 500 Mg, 60'S
------------------------------------------------------------------------
Biaxin XL, Filmtab Tab,        00074-3165-11   Q1 2014-Q4 2015
 500 Mg, 1010'S
------------------------------------------------------------------------
Biaxin XL 500Mg(114)          00074-3165-14   Q1 2014-Q4 2015
------------------------------------------------------------------------
Biaxin XL, Filmtab Tabs,       00074-3165-41   Q1 2014-Q4 2015
 500Mg, 414'S
------------------------------------------------------------------------
Biaxin XL, Filmtab             00074-3165-60   Q1 2014-Q4 2015
 Tablets, 500 Mg, 60'S
------------------------------------------------------------------------
Biaxin OS, 250Mg/5Ml,          00074-3188-13   Q2 2014-Q3 2014, Q1 2016-
 100ML                                          Q2 2018
------------------------------------------------------------------------
Biaxin OS 250Mg/5Ml, 50ML      00074-3188-50   Q2 2014-Q3 2014, Q1 2016-
                                                Q2 2018
------------------------------------------------------------------------
Biaxin Filmtab Tablets,        00074-3368-60   Q1 2014, Q3 2014, Q1 2015-
 250 Mg, 60'S                                   Q3 2015
------------------------------------------------------------------------
Cardizem LA , Tablets, 120     00074-3045-30   Q1 2014-Q3 2014
 Mg, 30'S
------------------------------------------------------------------------
Cardizem LA , Tablets, 120     00074-3045-90   Q1 2014-Q3 2014
 Mg, 90'S
------------------------------------------------------------------------
Cardizem LA , Tablets, 180     00074-3061-30   Q1 2014
 Mg, 30'S
------------------------------------------------------------------------
Cardizem LA , Tablets, 180     00074-3061-90   Q1 2014
 Mg, 90'S
------------------------------------------------------------------------
Cardizem LA , Tablets, 240     00074-3062-30   Q1 2014
 Mg, 30'S
------------------------------------------------------------------------
Cardizem LA , Tablets, 240     00074-3062-90   Q1 2014
 Mg, 90'S
------------------------------------------------------------------------
Cardizem LA , Tablets, 300     00074-3063-30   Q1 2014
 Mg, 30'S
------------------------------------------------------------------------
Cardizem LA , Tablets, 300     00074-3063-90   Q1 2014
 Mg, 90'S
------------------------------------------------------------------------
Cardizem LA , Tablets, 360     00074-3064-30   Q1 2014-Q2 2014
 Mg, 30'S
------------------------------------------------------------------------
Cardizem LA , Tablets, 360     00074-3064-90   Q1 2014-Q2 2014
 Mg, 90'S
------------------------------------------------------------------------
Cardizem LA , Tablets, 420     00074-3069-30   Q1 2014
 Mg, 30'S
------------------------------------------------------------------------
Cardizem LA, Tablets, 420      00074-3069-90   Q1 2014
 Mg, 90'S
------------------------------------------------------------------------
Depacon 500Mg (100Mg/1ML)      00074-1564-10   Q1 2016, Q4 2016-Q4 2017
 105ML SDV
------------------------------------------------------------------------
Depakene 250Mg 100Cap          00074-5681-13   Q1 2014, Q3 2014-Q4 2018
------------------------------------------------------------------------
Depakene OS 250Mg/5ML,         00074-5682-16   Q3 2014-Q4 2018
 16Oz
------------------------------------------------------------------------
Depakote ER 250Mg 1010Tab     00074-3826-11   Q1 2015, Q4 2018
------------------------------------------------------------------------
Depakote ER 250Mg 100Tab       00074-3826-13   Q1 2015, Q4 2018
------------------------------------------------------------------------
Depakote, Sprinkle             00074-6114-11   Q1 2015-Q4 2018
 Capsule, 125 Mg, 10-10
------------------------------------------------------------------------
Depakote Sprinkle Capsule,     00074-6114-13   Q1 2015-Q4 2018
 125Mg, 100
------------------------------------------------------------------------
Depakote 125Mg 100Tab          00074-6212-13   Q1 2014, Q3 2014-Q4 2018
------------------------------------------------------------------------
Depakote 250Mg 100Tab          00074-6214-13   Q1 2014, Q3 2014-Q4 2018
------------------------------------------------------------------------
Depakote 250Mg 500Tab          00074-6214-53   Q1 2014, Q3 2014-Q4 2018
------------------------------------------------------------------------
Depakote 500Mg 100Tab          00074-6215-13   Q1 2014, Q3 2014-Q4 2018
------------------------------------------------------------------------
Depakote 500Mg 500Tab          00074-6215-53   Q1 2014, Q3 2014-Q4 2018
------------------------------------------------------------------------
Depakote ER 500Mg 10X10Tab     00074-7126-11   Q4 2014-Q1 2015, Q1 2017-
                                                Q3 2017, Q4 2018
------------------------------------------------------------------------
Depakote ER 500Mg 100Tab       00074-7126-13   Q4 2014-Q1 2015, Q1 2017-
                                                Q3 2017, Q4 2018
------------------------------------------------------------------------
Depakote ER 500Mg 500Tab       00074-7126-53   Q4 2014-Q1 2015, Q1 2017-
                                                Q3 2017, Q4 2018
------------------------------------------------------------------------
Humira 40Mg/0.8ML (2           00074-3799-02   Q2 2016-Q4 2018
 Syringes)
------------------------------------------------------------------------
Humira Ped Crohns Starter      00074-3799-03   Q2 2016-Q4 2018
 Pack, 40Mg
------------------------------------------------------------------------
Humira Ped Crohns Starter      00074-3799-06   Q2 2016-Q4 2018
 Pack, 40Mg
------------------------------------------------------------------------
Humira 40Mg/0.8 ML (2          00074-4339-02   Q2 2016-Q4 2018
 Pens)
------------------------------------------------------------------------
Humira, Crohn's, 40Mg/0.8      00074-4339-06   Q2 2016-Q4 2018
 ML (6 Pens)
------------------------------------------------------------------------
Humira, Psoriasis, 40Mg/       00074-4339-07   Q2 2016-Q4 2018
 0.8ML (4 Pens)
------------------------------------------------------------------------
Humira, Single Dose            00074-6347-02   Q2 2016-Q4 2018
 Syringe, 10 Mg/0.2ML
------------------------------------------------------------------------
Humira 20Mg/0.4ML (2           00074-9374-02   Q2 2016-Q4 2018
 Syringes)
------------------------------------------------------------------------
K-Tab, Filmtabs, 8Meq,         00074-3058-41   Q3 2018
 600Mg, 100Ct
------------------------------------------------------------------------
K-Tab, Filmtabs, 8Meq,         00074-3058-46   Q3 2018
 600Mg, 1000Ct
------------------------------------------------------------------------
Marinol 2.5 Mg Capsules,       00051-0021-21   Q2 2016
 60'S
------------------------------------------------------------------------
Marinol 5 Mg Capsules,         00051-0022-21   Q3 2018
 60'S
------------------------------------------------------------------------
Marinol 10 Mg Capsules,        00051-0023-21   Q2 2014, Q3 2017
 60'S
------------------------------------------------------------------------
Mavik, Tablets, 1 Mg,          00074-2278-13   Q4 2014, Q2 2015
 100'S
------------------------------------------------------------------------
Niaspan, Tablets, 500 Mg,      00074-3074-90   Q1 2014, Q2 2015, Q1 2016-
 90'S                                           Q3 2016, Q1 2017-Q4 2018
------------------------------------------------------------------------
Niaspan, Tablets, 750 Mg,      00074-3079-90   Q1 2014, Q4 2014, Q2 2015-
 90'S                                           Q2 2016, Q4 2016-Q4 2018
------------------------------------------------------------------------
Niaspan, Tablets, 1000 Mg,     00074-3080-90   Q1 2014, Q1 2015-Q2 2015,
 90'S                                           Q1 2016-Q3 2016, Q1 2017-
                                                Q4 2018
------------------------------------------------------------------------
Niaspan, Tablets, 500Mg,       00074-3265-90   Q4 2017-Q4 2018
 90'S
------------------------------------------------------------------------
Niaspan, Tablets, 750Mg        00074-3274-90   Q1 2018-Q4 2018
 90'S
------------------------------------------------------------------------
Niaspan, Tablets, 1000Mg       00074-3275-90   Q4 2017-Q4 2018
 90'S
------------------------------------------------------------------------
Prometrium 100 Mg              00032-1708-01   Q2 2016-Q4 2018
 Capsules, 100'S
------------------------------------------------------------------------
Prometrium 200 Mg              00032-1711-01   Q2 2016-Q4 2018
 Capsules, 100'S
------------------------------------------------------------------------
Simcor 500Mg/20Mg, 90Tab       00074-3312-90   Q3 2014
------------------------------------------------------------------------
Simcor 1000Mg/20Mg, 90Tab      00074-3455-90   Q1 2014, Q3 2014
------------------------------------------------------------------------
Tarka ER 2Mg/180Mg, 100Tab     00074-3287-13   Q2 2015-Q4 2015, Q2 2016-
                                                Q4 2016, Q2 2017-Q4
                                                2017, Q2 2018-Q4 2018
------------------------------------------------------------------------
Tarka 1Mg/240Mg, 100Tab        00074-3288-13   Q2 2015-Q4 2015, Q2 2016-
                                                Q4 2018
------------------------------------------------------------------------
Tarka ER 2Mg/240Mg, 100Tab     00074-3289-13   Q1 2014, Q2 2015-Q4 2015,
                                                Q2 2016-Q4 2016, Q2 2017-
                                                Q4 2017, Q2 2018-Q4 2018
------------------------------------------------------------------------
Tarka ER 4Mg/240Mg, 100Tab     00074-3290-13   Q1 2014, Q1 2015-Q3 2015,
                                                Q1 2016-Q2 2016, Q4 2016-
                                                Q2 2017, Q4 2017-Q3 2018
------------------------------------------------------------------------
Tricor, Tablets, 145Mg,        00074-3189-90   Q3 2018
 90Ct Btl
------------------------------------------------------------------------
Tricor, Tablets, 48 Mg,        00074-6122-90   Q4 2014-Q1 2015
 90'S
------------------------------------------------------------------------
Tricor, Tablets, 145 Mg,       00074-6123-90   Q3 2018
 90'S
------------------------------------------------------------------------
Trilipix, Delayed Release      00074-3161-90   Q2 2017-Q4 2017, Q2 2018-
 Cap, 45Mg 90Ct                                 Q4 2018
------------------------------------------------------------------------
Trilipix, Delayed Release      00074-9189-90   Q3 2018-Q4 2018
 Cap, 135Mg 90'S
------------------------------------------------------------------------
Trilipix, Delayed Release      00074-9642-90   Q3 2014-Q4 2014, Q2 2015-
 Cap, 45Mg 90'S                                 Q3 2015, Q1 2016, Q3
                                                2016-Q4 2016, Q2 2017-Q4
                                                2017, Q2 2018-Q4 2018
------------------------------------------------------------------------
Zemplar, Capsules, 2 Mcg,      00074-4314-30   Q3 2014-Q1 2015, Q3 2015-
 30'S                                           Q4 2015, Q2 2016-Q4
                                                2016, Q2 2017, Q4 2017-
                                                Q4 2018
------------------------------------------------------------------------
Zemplar, Capsules, 4 Mcg,      00074-4315-30   Q2 2014-Q4 2015
 30'S
------------------------------------------------------------------------
Zemplar, Capsules, 1 Mcg,      00074-4317-30   Q4 2014, Q2 2015, Q4
 30'S                                           2015, Q2 2016, Q1 2018-
                                                Q4 2018
------------------------------------------------------------------------

                medicaid drug rebate program compliance
    Question. I am concerned about recent reports and legal settlements 
surrounding drug manufacturers' failure to comply fully with the 
requirements of the MDRP. for example, an analysis by the U.S. 
Department of Health and Human Services office of Inspector General 
found that between 2012 and 2016 taxpayers may have overpaid by as much 
as $1.3 billion for 10 potentially misclassified drugs. That is why I 
introduced the Right Rebate Act with Chairman Grassley to prevent drug 
manufacturers from manipulating Medicaid to increase their profits. 
However, I continued to be concerned about oversight and manufacturer 
compliance with the requirements of the Medicaid Drug Rebate Program. 
Accordingly, please describe the following:

    Your company's current compliance plan and procedures used to 
ensure compliance with the requirements of the Medicaid Drug Rebate 
Program including internal audits or other checks you use to identify 
compliance vulnerabilities.

    Answer. AbbVie has established and maintains a comprehensive 
compliance plan and procedures to ensure MDRP compliance, the core 
components of which include policies and procedures relating to MDRP 
issues, routine internal and external monitoring and auditing, and a 
dedicated governance team to monitor and address any potential MDRP 
issues.

    Question. Any past or ongoing issues of non-compliance.

    Answer. We are not aware of past or ongoing issues of non-
compliance with MDRP legal requirements.

    Question. Any corrective actions taken to address identified 
problems or issues of noncompliance with the MDRP and how such steps 
were communicated to the Centers for Medicare and Medicaid Services.

    Answer. We are not aware of past or ongoing issues of non-
compliance with MDRP legal requirements.

    Question. Any steps taken to improve compliance and ensure that all 
Medicaid drug rebates owed to the Federal Government and the States are 
paid in full.

    Answer. AbbVie conducts periodic reviews of its compliance plan and 
updates its policies, procedures, and monitoring plans as needed to 
ensure the company's continued implementation of MDRP legal 
requirements.
                 bonus payments tied to specific drugs
    Question. I am concerned by the potential for employee financial 
incentives to encourage high launch prices and price increases for 
prescription drugs.

    Is your salary, bonus, or other compensation tied to sales or 
revenue targets of a single product your company sells? Has it ever 
been? If yes, please state the product or products to which your 
salary, bonus or other compensation was tied.

    Is your salary, bonus, or other compensation tied to either revenue 
or net income of the company as a whole? Has it ever been? If yes, 
please explain what assumptions about price increases are used when the 
compensation committee sets revenue or net income goals. Does the 
compensation committee provide any guidance to executives in regards to 
the amount of revenue that the company will generate from price 
increases versus volume growth?

    Answer. To determine Mr. Gonzalez's 2018 annual incentive 
compensation (sometimes referred to as a bonus), net revenues, income 
before taxes, and Humira sales were three of several quantitative 
financial metrics that were considered in addition to qualitative 
factors. At most, a single quantitative financial metric had the 
potential to impact up to 3 percent of Mr. Gonzalez's total 
compensation, subject to additional qualitative and relative analyses. 
No other compensation element, beyond the annual incentive 
compensation, includes Humira sales, revenue, or net income as a 
performance metric. While some specific details have differed somewhat, 
the foregoing has generally been true in prior years as well.

                                 ______
                                 
              Questions Submitted by Hon. Robert Menendez
    Question. When new products enter the market, do drug companies set 
high initial rebates and then provide deep rebates in order to gain 
access to insurance plan's formularies?

    Answer. Over the last 2 years, AbbVie has brought Mavyret and 
Orilissa to patients. Mavyret is for the treatment of adults with 
chronic hepatitis C virus (HCV) infection across all major genotypes, 
and Orilissa is the first and only oral gonadotropin-releasing hormone 
antagonist specifically developed for women with moderate to severe 
endometriosis pain. Mavyret was introduced with a list price below 
competitive alternatives and Orilissa was introduced at a list price 
below the current standard of care.

    Rebates are a form of price competition that results from the 
aggressive negotiations that occur between health plans (and their 
representative PBMs) and pharmaceutical companies to provide patients 
with access to medicines and treatments that can best help patients 
manage their medical conditions. Plans/PBMs create formularies to list 
brand and generic medicines.

    Question. If CMS finalizes the rebate rule, do you anticipate 
future products entering the market with significantly lower initial 
list prices?

    Answer. There has been significant discussion over the past several 
months about proposals to eliminate rebates from Medicare Part D, 
Medicaid, and the commercial market culminating in the administration's 
publication of a proposed rule to ``expressly exclud[e] from safe 
harbor protection under the Anti-Kickback Statute (AKS) rebates on 
prescription drugs paid by manufacturers to pharmacy benefit managers 
(PBMs), Part D plans, and Medicaid managed care organizations. The 
proposal would create a new safe harbor protecting discounts offered to 
patients at the pharmacy counter. Finally, the proposal would create 
new safe harbor protection for fixed fee services arrangements between 
manufacturers and PBMs.''

    AbbVie is encouraged by the goals of the proposed rule to ensure 
manufacturer discounts are reflected in and reduce patient cost sharing 
under Part D. While we believe the rule is an important step in the 
right direction, we also believe more should be done to help reduce the 
out-of-pocket cost burden on Medicare Part D patients.

    As for what the elimination of rebates might mean to the overall 
health care system or pharmaceutical companies, it is premature to 
comment on these items until the Administration's rule is finalized, 
implementation timelines are solidified and there are specific details 
regarding how a new system without rebates will be structured and 
function.

                                 ______
                                 
              Questions Submitted by Hon. Thomas R. Carper
    Question. What are your recommendations for lowering prices for the 
40 percent of drugs that do not offer rebates in Medicare Part D?

    Answer. A majority of the discussion about the cost of prescription 
drugs has been focused on list prices. We agree that price should be 
part of the discussion, however we also know that solutions targeting 
list price alone are not enough. Our experience in launching a low list 
price HCV medicine made it clear to AbbVie and patients that list price 
reductions will not always address patient affordability and access.

    Providing discounts to the patient at the point of sale is an 
effective way of ensuring that patients can see lower out-of-pocket 
costs. However, this is just the start. AbbVie believes that more must 
be done.

    The Medicare Part D benefit design contributes to making innovative 
therapies cost-prohibitive for Medicare patients because patients are 
charged out-of-pocket costs based on a medicine's list price, which 
does not reflect the rebates that Medicare receives.

    AbbVie believes it is important to alleviate the burdens that 
patients face due to Medicare Part D out-of-pocket costs. AbbVie 
supports solutions like a patient out-of-pocket cap in Part D and 
smoothing patient out-of-pocket payments over a full year, so patients 
have some predictability with respect to their out-of-pocket costs.

    In addition, AbbVie is prepared to step up and discuss how 
companies like ours can shoulder more of the burden of a patient's out-
of-pocket expenses.

    As policymakers consider the impact of addressing out-of-pocket 
costs in Medicare Part D, questions may arise around whether it will 
lead to unnecessary utilization and wasteful spending. for specialty 
medicines, increased utilization should not be misunderstood as 
unnecessary or wasteful. Part D plans have tools, like step therapy 
requirements for patients to first try lower cost alternatives before a 
specialty medicine would be covered and prior authorization 
requirements before a specialty medicine would be covered, to manage 
the utilization of the majority of higher cost specialty medicines. 
These tools ensure patients try a less costly medication first and have 
met the clinical criteria for taking the specialty drug prescribed and 
serve the function that an out-of-pocket cost obligation on patients 
might serve to prevent unnecessary use.

    Question. In the health insurance plans that you offer your 
employees, do you ask your insurers to pass through the full 
manufacturer rebates to the beneficiaries?

    Answer. AbbVie's benefit plans are structured to ensure employees 
share in the cost of their prescription drugs but are also able to 
access and afford their medicines, with the goal of maximizing 
prescription drug adherence.

    Currently our maximum co-pays and out-of-pocket maximums ensure 
patient access and allow us to utilize rebates to reduce premiums. Our 
benefit includes a deductible and 25-percent co-pay for prescription 
medicines that is capped at $125 for a 30-day supply. For mail order or 
specialty pharmacy, there is a 20-percent co-pay that is capped at $250 
for a 90-day supply. Additionally, our benefit plans include an annual 
out-of-pocket maximum. Our prescription drug adherence levels are high 
year over year across many disease states.

    To increase transparency, members receive a receipt at retail or 
via mail/specialty pharmacies that reflects their share of the 
discounted price of the drug.

    AbbVie has considered the impact of passing through rebates to 
employees and have found a minimal impact on employee out-of-pocket 
expenses for all medicines, including specialty. We have found that it 
would only reduce employee spending if the rebate reduced the co-
payment obligation below $125 for drugs filled at retail or $250 for 
mail order or specialty drugs.

    Employees who would benefit the most in this scenario would be 
those in high deductible health plans before they meet their 
deductible, however it could slow the time in which they would reach 
their deductible.

    While we have found that providing rebates at point of sale is most 
beneficial to enrollees whose benefit design does not include a maximum 
co-pay and therefore may not be beneficial to AbbVie employees, we are 
continuing to assess the impact in a manner that ensures we can 
maintain the current employee costsharing levels in our benefit design 
that drive adherence.

    Question. The systems for pricing and distributing drugs are opaque 
and difficult to understand. What are your recommendations for 
increasing transparency in how your companies set the list prices for 
drugs, and for improving transparency in the supply chain for 
prescription drugs? Would you support federal standards for 
transparency in setting the list prices for drugs?

    Answer. AbbVie supports transparency that is accurate, timely, 
comprehensive and meaningful to patients as they make better-informed 
decisions about their health care. This includes broad transparency 
across the entire health-care system and consistent requirements, 
including for all entities in the drug supply chain, rather than a 
narrow focus on one individual sector. It is also important that any 
new transparency requirements are prospective and balanced with 
appropriate protections for confidential, proprietary information so as 
not to undermine competition in the marketplace. As Congress considers 
approaches to address transparency at the Federal level, AbbVie 
welcomes further discussion on this important topic.

    Question. In nearly every sector of the health-care industry, 
Medicare, Medicaid, employers, and insurers are moving away from fee-
for-service payments to reimbursements based on value and performance. 
Prescription drugs and medical devices were the glaring exceptions to 
this trend until recently. How many of your drugs are included in 
valuebased contracts and how many patients are benefiting from them? 
How do these valuebased contracts work to lower drug prices for both 
patients and taxpayers?

    Answer. Value-based arrangements can be an effective and market-
based solution to managing overall health-care costs when driven by 
patient outcomes. Studies have found that 38 percent of payers with 
outcomes-based contracts experience improved patient outcomes and 33 
percent experience plan health-care cost savings. Additionally, plans 
with outcomes-based contracts have been found to have a 28 percent 
lower patient co-payment. All of these factors work towards moving 
payment for prescription medicines away from volume-based approaches to 
value-based models in a manner that appropriately balances patient 
access with the appropriate use of medications to lower overall health-
care costs.

    At AbbVie, we believe all our products provide value to patients 
and the larger health care system and are interested in the 
possibilities that could arise through value-based contracting. To 
further foster value-based arrangements, we support the reforms 
included in the Patient Affordability, Value and Efficiency (PAVE) Act, 
introduced by Senators Cassidy (R-LA) and Warner (D-VA).

    Question. Last year, Senator Portman and I did an investigation on 
the pricing of an opioid overdose reversal drug called EVZIO, 
manufactured by Kaleo. Kaleo increased the price of EVZIO from $575 in 
2014 to $4,100 in 2017. We found that the best price Medicare was able 
to get for EVZIO, about $4,000, was much higher than the price other 
federal programs and private insurers were able to get. It seemed that 
Kaleo was able to get this higher price of $4,000 from Medicare by 
helping doctors fill out paperwork showing that the drug was medically 
necessary, even though there are cheaper alternatives on the market. As 
a result of the investigation, Kaleo announced it will bring a generic 
version of the drug to market at only $168 per pack. Are any of your 
companies providing medical necessity paperwork to doctors in order to 
get your drugs covered by Medicare?

    Answer. Unlike the scenarios raised in this question, AbbVie does 
not have a practice of completing medical necessity sections on any 
reimbursement forms, purporting to make medical necessity 
determinations that should be made by physicians, or submitting medical 
necessity forms to payors on behalf of patients or physicians.

    Question. In 2017, the Rand Corporation estimated that biosimilar 
drugs, which are competitors to complex, biologic drugs, could save the 
United States more than $50 billion over the next decade. Some of you 
have also argued that increasing the use of biosimilar drugs would help 
lower drugs costs for consumers and taxpayers. What is delaying the 
uptake of biosimilar drugs in the United States? What policies do you 
recommend to increase the development of biosimilar drugs?

    Answer. AbbVie believes that FDA's current, patient-centered and 
science-based approach to the development of standards governing the 
approval of biosimilars--including interchangeable biosimilars--helps 
to build a sustainable biosimilar market as patients and health care 
providers become more exposed to, and comfortable with, these products. 
The agency's approach best ensures the approval of quality, safe, and 
effective biosimilar products--products that will instill confidence 
among patients and prescribers. A robust and competitive biologic 
marketplace cannot survive without this stakeholder confidence and 
support.

    Any policies regarding the biologics market must take into 
consideration the fundamental differences between small molecule 
generics and biosimilars. Consequently, competition between biosimilars 
and their reference products will necessarily more closely resemble 
brand-to-brand competition. A key principle for encouraging appropriate 
market competition for biological products, then, is ensuring a level 
playing field for all biologic products. Artificially favoring either 
biosimilars or innovator biologics in coverage or reimbursement creates 
market inefficiencies by reducing incentives to compete on price. 
Moreover, policies designed to artificially drive usage of either the 
biosimilar or the reference biologic risk confusing stakeholders 
regarding the clear regulatory distinctions between biosimilars and 
small-molecule generics. Robust competition should therefore be driven 
by an increasing number of innovator and biosimilar products competing 
to treat disease at the lowest possible cost.

                                 ______
                                 
             Questions Submitted by Hon. Benjamin L. Cardin
    Question. The United States is one of the only countries in the 
world to allow prescription drug manufacturers to advertise directly to 
consumers through magazines, billboards, radio, and television 
commercials. While I will not argue that it is beneficial to educate 
consumers about an unfamiliar disease and encourage them to seek 
medical help, most commercials from all of your companies recommend 
asking about a specific brand name drug, not a medical condition. 
Furthermore, even if your advertisements follow all FDA rules and list 
medication side effects, they also almost always list these while a 
smiling, apparently healthy person is walking on a beach.

    Researchers say that this type of imagery, combined with viewing 
hours of drug commercials each month, leads consumers to underestimate 
the risks associated with medications. for the past decade, studies 
have shown that aggressive direct-toconsumer advertising is associated 
with rising drug prices and an increase in inappropriate drug 
prescriptions.

    Since researchers have concluded that consumers are 
misunderstanding the benefits and risks described in your ads, what 
further policies could help you and your colleagues ensure that you are 
educating patients in a clear manner?

    Answer. We believe it is unlikely that DTC advertising would lead 
to an ``increase in inappropriate prescriptions'' for AbbVie's largely 
specialty-product portfolio. Both commercial insurance and Part D plans 
have tools, like step therapy requirements for patients to first try 
lower cost alternatives before a specialty medicine would be covered 
and prior authorization requirements before a specialty medicine would 
be covered to manage the utilization of the majority of higher cost 
specialty medicines. These tools ensure patients try a less costly 
medication first and have met the clinical criteria for taking the 
specialty drug prescribed.

    Further, we believe that consumers understand the benefits and 
risks described in AbbVie's advertisements. AbbVie goes beyond the FDA 
regulations to ensure its advertising it accurate, truthful, not 
misleading, and reflects an appropriate balance between the risks and 
benefits of the drugs. This includes complying with PhRMA's voluntary 
principles on direct to consumer advertising.\2\ Some of the key 
principles addressing the issues of educating patients in a clear 
manner include:
---------------------------------------------------------------------------
    \2\ See http://phrmadocs.phrma.org/files/dmfile/PhRMA--Guiding--
Principles_2018.pdf.

          Companies that choose to feature actors in the roles of 
        health-care professionals in a DTC television or print 
        advertisement that identifies a particular product should 
        acknowledge in the advertisement that actors are being used. 
        Likewise, if actual health-care professionals appear in such 
        advertisements, the advertisement should include an 
        acknowledgment if the health-care professional is compensated 
---------------------------------------------------------------------------
        for the appearance.

          DTC television advertising that identifies a product by name 
        should clearly state the health conditions for which the 
        medicine is approved and the major risks associated with the 
        medicine being advertised.

          DTC television and print advertising should be designed to 
        achieve a balanced presentation of both the benefits and the 
        risks associated with the advertised prescription medicine. 
        Specifically, risks and safety information, including the 
        substance of relevant boxed warnings, should be presented with 
        reasonably comparable prominence to the benefit information, in 
        a clear, conspicuous and neutral manner, and without 
        distraction from the content. In addition, DTC television 
        advertisements should support responsible patient education by 
        directing patients to health care professionals as well as to 
        print advertisements and/or websites where additional benefit 
        and risk information is available.

          All DTC advertising should respect the seriousness of the 
        health conditions and the medicine being advertised.

    AbbVie believes these are important principles that all 
pharmaceutical advertisements should follow. Our approach of listening 
to, and learning from, consumers, caregivers, physicians and other 
health-care professionals continues to confirm our belief that 
accurate, balanced and timely information about our prescription 
medicines and the conditions they treat is an essential component of 
our commitment to putting patient health first.
           pharmaceutical companies continue to raise prices
    Question. As you are well aware, high prescription drug prices are 
the number one concern for Americans and their families. According to 
the Organization for Economic Cooperation and Development, the average 
American spends around $1,208 annually on prescription drugs. There 
have been several instances where brand name or even generic drugs that 
have been on the market for years continue to increase in price.

    One of the most well known examples is Mylan's increase of the 
price of EpiPen from less than $100 in 2007 to more than $600 in 2016. 
Another example, is the everincreasing price of insulin. Sanofi 
increased the price of a vial of Lantus from $88.20 in 2007 to $307.20 
in 2017. And those are just a small sample of price increases.

    Why don't we see price decreases for drugs that have been on the 
market for years without new formulations or added benefit?

    Answer. Price often does decrease for drugs that have been on the 
market for years. The U.S. has a robust and well-functioning system 
with fast entry of generic medicines following the expiration of patent 
and market exclusivities for brand medications. When generics medicines 
enter the market price reductions can be dramatic. In fact, GAO has 
found that prices are typically reduced by 20 percent for each new 
generic entrant to the market. From 2005 to 2013 prices of medicines 
commonly used to prevent cardiovascular disease dropped 92 percent. The 
daily cost of the top 10 therapeutic classes of medicines most commonly 
used by Medicare Part D enrollees dropped from $1.50 to $0.77 from 2006 
to 2013.

    In addition to dramatic decreases in price, generic uptake is swift 
in the U.S. When a generic version of a medicine becomes available for 
the first time, it captures an average of three-quarters of the market 
within 3 months. Some generics captures as much as 90 percent in that 
same time period. Utilization is also the highest in the U.S. when 
compared to uptake in other markets, such as the UK, France, Japan, 
Germany, and Australia. According to the 2018 Medicare Trustees Report, 
the generic utilization rate for Part D beneficiaries has steadily 
increased each year, from 75 percent in 2010 to 88 percent in 2017.

    Competition is also robust among branded products. From 2005 to 
2011, the time only one medicine was available in its class declined 
from a median of 10 years in the 1970s to close to 2 years from 2005-
2011. Half of second medicines were approved within 2.3 years and one 
quarter were approved within just 4 months. These competitive forces 
lead to manufacturers offering discounts. An analysis by IQVIA found 
that net prices for brands continued to increase more slowly than 
invoice prices from 2013 to 2016, with average price increases for 
brands at 9.2 percent (down from 12 percent in 2015) and net price 
growth increases at 3.5 percent. For the same year, the analysis found 
that rebates, discounts, and other price concessions offset price 
growth for brand medicines by 62 percent.
                             pay for delay
    Question. Pay for delay is a tactic that more and more branded drug 
manufacturers have been using to stifle competition from lower-cost 
generic manufacturers. This allows you to sidestep competition by 
offering patent settlements that pay generic companies not to bring 
lower-cost alternatives to market.

    These ``pay-for-delay'' patent settlements benefit both brand-name 
pharmaceutical companies by helping them avoid costly patent litigation 
and general manufacturers by rewarding them a hefty sum to delay 
entering the market with a cheaper drug alternative. However, these 
deals do not benefit consumers. According to an FTC study, these 
anticompetitive deals cost consumers and taxpayers $3.5 billion in 
higher drug costs every year.

    Does your company partake in pay-for-delay settlements?

    Why would a pharmaceutical company enter into a pay-for delay 
agreement?

    Do you think these agreements stifle competition and prevent 
generic alternatives to your branded medications?

    Answer. ``Pay-for-delay'' is not a self-defining phrase. With 
respect to the term ``pay,'' patent litigation settlements, like all 
litigation settlements, involve compromise in which both sides believe 
they are getting value from the resolution. There is no definition 
explaining the circumstances under which that value would implicate the 
term ``pay'' in ``pay-fordelay'' for purposes of these questions. And 
with respect to ``delay'' virtually all patent settlements provide for 
the generic competitor to enter the market before the expiration of the 
patent at issue. So if the alternative resolution of a patent lawsuit 
would be the innovator company continuing to enforce its patent until 
expiration, then such a settlement, no matter what value is exchanged, 
would actually accelerate competition, not delay it.
                            drug rebate rule
    Question. In January, the Department of Health and Human Services' 
(HHS) office of Inspector General (OIG) promulgated a new regulation to 
remove regulatory safe harbor protections under the Anti-Kickback 
Statute (AKS) for rebates on prescription drugs rebates paid by 
manufactures to PBMs under Medicare Part D and for Medicaid managed 
care organizations (MCOs). The OIG proposal attempts to ban most 
rebates by eliminating their regulatory protections.

    The rule is predicted to increase net drug costs in its early 
years. The CMS actuaries estimate it would cost $196 billion over 10 
years. Despite this high price tag, the beneficiary benefits are 
limited. The proposed rule notes that under the CMS Actuary's analysis, 
the majority of beneficiaries would see an increase in their total out-
of-pocket payments and premium costs; reductions in total cost sharing 
will exceed total premium increases.

    I wanted to ask a question about the administration's rebate rule, 
which I understand that many of the drug manufacturers, and your main 
trade association, strongly support. According to an analysis of the 
rule by the Office of Actuaries at CMS, drug manufacturers are likely 
to initially retain 15 percent of the current rebates as higher net 
drug prices.

    Given that estimate, can you provide the committee with any 
assurances that prices will not increase under this proposed rule?

    Answer. There has been significant discussion over the past several 
months about proposals to eliminate rebates from Medicare Part D, 
Medicaid, and the commercial market culminating in the administration's 
publication of a proposed rule to ``expressly exclude[e] from safe 
harbor protection under the Anti-Kickback Statute (AKS) rebates on 
prescription drugs paid by manufacturers to pharmacy benefit managers 
(PBMs), Part D plans, and Medicaid managed care organizations. The 
proposal would create a new safe harbor protecting discounts offered to 
patients at the pharmacy counter. Finally, the proposal would create 
new safe harbor protection for fixed fee services arrangements between 
manufacturers and PBMs.''

    AbbVie is encouraged by the goals of the proposed rule to ensure 
manufacturer discounts are reflected in and reduce patient cost sharing 
under Part D. While we believe the rule is an important step in the 
right direction, we also believe more should be done to help reduce the 
out-of-pocket cost burden on Medicare Part D patients.

    As for what the elimination of rebates might mean to the overall 
health care system or pharmaceutical companies, it is premature to 
comment on these items until the Administration's rule is finalized, 
implementation timelines are solidified and there are specific details 
regarding how a new system without rebates will be structured and 
function.

                                 ______
                                 
               Questions Submitted by Hon. Sherrod Brown
    Question. According to an article recently published in the Journal 
of the American Medical Association, medical marketers spent nearly $30 
billion dollars in 2016, up from $17 billion in 1997. Direct-to-
Consumer (DTC) advertising had the biggest percentage increase: from 
$2.1 billion, or 11.9 percent of all medical marketing, in 1997 to $9.6 
billion, or 32 percent of total spending, in 2016.

    Can each of you please provide what your ratio of spending on sales 
and marketing to research and development is today?

    Answer. AbbVie spends more on research and development than on 
global sales, marketing, and promotion costs. The global sales, 
marketing, and promotion spend in 2018 across all AbbVie products was 
$4.24 billion. This is less than the $5.26 billion AbbVie spent on 
research and development in 2018. And AbbVie's research and development 
spend does not include acquired inprocess research and development 
($424 million in 2018) or money invested externally for technology, 
pharmaceutical compounds, or acquisitions. for example, AbbVie acquired 
Pharmacyclics for $20.8 billion in 2015 and Stemcentrx for $6.4 billion 
in 2016. The acquisition of both companies enhanced AbbVie's pipeline, 
research and development, and clinical programs.

                             price-gouging
    Answer. Sanofi, as I understand it, has made a pledge to the public 
to limit its price increases to the national health expenditures growth 
projection.

    Would your company commit to a cap on annual price increases as 
part of your PhRMA membership criteria?

    Answer. With respect to the question's proposed collective 
agreement by PhRMA members to cap annual price increases, we note that 
in 1993, PhRMA (then known as PMA, the Pharmaceutical Manufacturers 
Association) sought review of such a proposal from the Antitrust 
Division of the Department of Justice. The Department of Justice opined 
that the proposed agreement for PhRMA members to collectively agree to 
limit their price increases would be per se unlawful under federal 
antitrust laws, even though the proposal was made ``in response to 
concerns about controlling health care costs.'' (Oct. 1, 1993 letter 
from Anne K. Bingaman, Assistant U.S. Attorney General, available at 
https://www.justice.gov/atr/response-pharmaceutical-manufacturers-
associationsrequest-business-review-letter (``The PMA proposal is an 
arrangement among competitors that limits individual pricing decisions 
on its face. . . . An agreement among independent competitors that 
interferes with free and open price competition by restraining 
individual pricing decisions is a per se violation of the Sherman 
Act.'').) The Department of Justice said it ``intend[ed] to bring suit 
to challenge the program if PMA and its members go forward with its 
proposal.'' AbbVie could not support a proposal that the Department of 
Justice is on record as saying is unlawful and against which it would 
file suit to block.

    As for individual action, the same Department of Justice opinion 
discussed above noted that, while collective agreements among 
competitors raised antitrust violations, an individual company's 
decision to limit its own price increases would not be problematic. 
AbbVie in January 2017 became one of the first pharmaceutical companies 
to commit to limiting increases of its list prices. AbbVie committed to 
not more than one, single-digit price increase annually. AbbVie has 
abided by that commitment.

    Question. What policies would you propose to help ensure lower 
launch prices for new drugs?

    Answer. A majority of the discussion about the cost of prescription 
drugs has been focused on list prices. We agree that price should be 
part of the discussion, however we also know that solutions targeting 
list price alone are not enough. Our experience in launching a low list 
price HCV medicine made it clear to AbbVie and patients that list price 
reductions will not always address patient affordability and access.

    Providing discounts to the patient at the point of sale is an 
effective way of ensuring that patients can see lower out-of-pocket 
costs. However, this is just the start. AbbVie believes that more must 
be done.

    The Medicare Part D benefit design contributes to making innovative 
therapies cost-prohibitive for Medicare patients because patients are 
charged out-of-pocket costs based on a medicine's list price, which 
does not reflect the rebates that Medicare receives.

    AbbVie believes it is important to alleviate the burdens that 
patients face due to Medicare Part D out-of-pocket costs. AbbVie 
supports solutions like a patient outof-pocket cap in Part D and 
smoothing patient out-of-pocket payments over a full year, so patients 
have some predictability with respect to their out-of-pocket costs.

    In addition, AbbVie is prepared to step up and discuss how 
companies like ours can shoulder more of the burden of a patient's out-
of-pocket expenses.

    As policymakers consider the impact of addressing out-of-pocket 
costs in Medicare Part D, questions may arise around whether it will 
lead to unnecessary utilization and wasteful spending. for specialty 
medicines, increased utilization should not be misunderstood as 
unnecessary or wasteful. Part D plans have tools, like step therapy 
requirements for patients to first try lower cost alternatives before a 
specialty medicine would be covered and prior authorization 
requirements before a specialty medicine would be covered, to manage 
the utilization of the majority of higher cost specialty medicines. 
These tools ensure patients try a less costly medication first and have 
met the clinical criteria for taking the specialty drug prescribed and 
serve the function that an out-of-pocket cost obligation on patients 
might serve to prevent unnecessary use.
                              transparency
    Question. In many of your testimonies, you mentioned that the 
current system of pharmacy benefit manager (PBM) back-end rebates 
rarely results in a scenario where the PBM passes on savings to 
consumers at the point of sale (POS). The administration recently 
proposed a rule to eliminate the anti-kickback statute safe harbor 
protections for these drug rebates.

    Do you agree that greater transparency should be required to 
understand how manufacturers and PBMs are negotiating prices and 
rebates to ensure that savings are passed down to beneficiaries?

    Answer. AbbVie supports price transparency across all stakeholders 
that is accurate, timely, comprehensive, and meaningful to patients as 
they make better-
informed decisions about their health care. This includes broad 
transparency across the entire health-care system and consistent 
requirements, including for all entities in the drug supply chain, 
rather than a narrow focus on one individual sector. It is also 
important that any new transparency requirements are prospective and 
balanced with appropriate protections for confidential, proprietary 
information so as not to undermine competition in the marketplace.
                                  pbms
    Question. An Axios article from March 7, 2019 highlights the fact 
that, while ``pharmaceutical companies put a lot of the blame for high 
drug prices on pharmacy benefit managers,'' many large pharmaceutical 
companies ``rely on PBMs to manage their own health-care benefits.''

    In your role as an employer, does your company contract with a 
pharmaceutical benefit manager (PBM) to administer the prescription 
drug benefits for your employees and negotiate lower drug costs on your 
behalf?

    For those of you who do use a PBM to help manage the prescription 
drug benefit for your employees, how do you utilize the rebates your 
PBM negotiates to lower health-care costs or drug costs for your 
employee plans and what does your company do with that savings? 
Specifically, do the savings go toward lowing premiums?

    For those of you who do use a PBM to help manage the prescription 
drug benefit for your employees, does your PBM offer point-of-sale 
rebates to your employees?

    Answer. AbbVie does use a PBM to manage pharmacy benefits for its 
employees in the U.S. AbbVie's benefit plans are structured to ensure 
employees share in the cost of their prescription drugs but are also 
able to access and afford their medicines, with the goal of maximizing 
prescription drug adherence.

    Currently our maximum co-pays and out-of-pocket maximums ensure 
patient access and allows us to utilize rebates to reduce premiums. Our 
benefit includes a deductible and 25-percent co-pay for prescription 
medicines that is capped per prescription at $125 for a 30-day supply. 
For mail order or specialty pharmacy, there is a 20-percent co-pay that 
is capped per prescription at $250 for a 90-day supply. Additionally, 
our benefit plans include an annual out-of-pocket maximum. Our 
prescription drug adherence levels are high year over year across many 
disease states.

    To increase transparency, members receive a receipt at retail or 
via mail/specialty pharmacies that reflects their share of the 
discounted price of the drug.

    AbbVie has considered the impact of passing through rebates to 
employees and have found a minimal impact on employee out-of-pocket 
expenses for all medicines, including specialty. We have found that it 
would only reduce employee spending if the rebate reduced the co-
payment obligation below $125 for drugs filled at retail or $250 for 
mail order or specialty drugs.

    Employees who would benefit the most in this scenario would be 
those in high deductible health plans before they meet their 
deductible, however it could slow the time in which they would reach 
their deductible.

    While we have found that providing rebates at point of sale is most 
beneficial to enrollees whose benefit design does not include a maximum 
co-pay and therefore may not be beneficial to AbbVie employees, we are 
continuing to assess the impact in a manner that ensures we can 
maintain the current employee cost-sharing levels in our benefit design 
that drive adherence.

                                 ______
                                 
             Questions Submitted by Hon. Sheldon Whitehouse
    Question. Please describe any policy changes you support that would 
result in your company lowering the list prices of its drugs.

    Answer. A majority of the discussion about the cost of prescription 
drugs has been focused on list prices. We agree that price should be 
part of the discussion, however we also know that solutions targeting 
list price alone are not enough. Our experience in launching a low list 
price HCV medicine made it clear to AbbVie and patients that list price 
reductions will not always address patient affordability and access.

    Providing discounts to the patient at the point of sale is an 
effective way of ensuring that patients can see lower out-of-pocket 
costs. However, this is just the start. AbbVie believes that more must 
be done.

    The Medicare Part D benefit design contributes to making innovative 
therapies cost-prohibitive for Medicare patients because patients are 
charged out-of-pocket costs based on a medicine's list price, which 
does not reflect the rebates that Medicare receives.

    AbbVie believes it is important to alleviate the burdens that 
patients face due to Medicare Part D out-of-pocket costs. AbbVie 
supports solutions like a patient out-of-pocket cap in Part D and 
smoothing patient out-of-pocket payments over a full year, so patients 
have some predictability with respect to their out-of-pocket costs.

    In addition, AbbVie is prepared to step up and discuss how 
companies like ours can shoulder more of the burden of a patient's out-
of-pocket expenses.

    As policymakers consider the impact of addressing out-of-pocket 
costs in Medicare Part D, questions may arise around whether it will 
lead to unnecessary utilization and wasteful spending. for specialty 
medicines, increased utilization should not be misunderstood as 
unnecessary or wasteful. Part D plans have tools, like step therapy 
requirements for patients to first try lower cost alternatives before a 
specialty medicine would be covered and prior authorization 
requirements before a specialty medicine would be covered, to manage 
the utilization of the majority of higher cost specialty medicines. 
These tools ensure patients try a less costly medication first and have 
met the clinical criteria for taking the specialty drug prescribed and 
serve the function that an out-of-pocket cost obligation on patients 
might serve to prevent unnecessary use.

    Question. How much does your company's research and development 
portfolio rely on taxpayer-funded research conducted by the National 
Institutes of Health (NIH)? How many of your company's products are 
based, at least in part, on NIH research, and how many are the result 
of research funded solely by your company?

    Answer. The NIH performs important basic research that helps 
scientific understanding. However, AbbVie spends its own money to do 
the vast majority of its drug development and clinical trial work, 
relying on the more than 8,000 people in research and development to 
understand complex diseases and advance medicine. for the eleven AbbVie 
drugs sold in the United States that have been approved since 2000, and 
the two AbbVie drugs currently under review by the FDA, only two 
received funding from the NIH for drug discovery. One of those drugs, 
Orilissa, was developed by Neurocrine. Neurocrine received NIH funding 
for drug development prior to AbbVie's collaboration with Neurocrine.

    For the second, Kaletra, AbbVie's predecessor Abbott Laboratories 
received an NIH discovery grant as part of an effort by the NIH to 
encourage collaborative research among pharmaceutical manufacturers and 
university research centers on protease inhibitors and to explore their 
potential to treat HIV, a then uncontrollable and fatal disease. This 
grant contributed to the development of one of the two active 
ingredients in the drug. This grant, however, represented less than 1 
percent of the total funding for Kaletra, with more than 99 percent of 
the funding coming from Abbott.

    In addition, for AbbVie's two oncology drugs--Venclexta and 
Imbruvica--AbbVie has worked cooperatively with the National Cancer 
Institute to conduct certain clinical trials. To date, these 
cooperative trials have not resulted in any FDA approved indications 
for these drugs.

    Question. In each of the last 5 years, how much has your company 
spent on research and development versus the advertising and marketing 
of your products?

    Answer. In each of the last four years, AbbVie has spent more on 
research and development than it has on sales and marketing.

----------------------------------------------------------------------------------------------------------------
                          2014               2015               2016               2017               2018
----------------------------------------------------------------------------------------------------------------
AbbVie Research      $3.297 billion     $4.285 billion     $4.385 billion     $5.007 billion     $5.259 billion
 and PDevelopment
----------------------------------------------------------------------------------------------------------------
Asset Impairments  .................  .................  .................  .................    $5.070 billion
----------------------------------------------------------------------------------------------------------------
Reported Research    $3.297 billion     $4.285 billion     $4.385 billion     $5.007 billion    $10.329 billion
 and Development
----------------------------------------------------------------------------------------------------------------
Acquired in-           $352 million       $150 million       $200 million       $327 million       $424 million
 process
 Presearch and
 development
----------------------------------------------------------------------------------------------------------------
Global Sales and     $3.652 billion     $3.800 billion     $3.674 billion     $3.830 billion    $4.239 billion
 PMarketing
----------------------------------------------------------------------------------------------------------------
* Sales and marketing includes the cost of AbbVie personnel in the sales and marketing field, related overhead,
  the cost to develop marketing and advertising materials, and the cost of placing advertisements.

    Question. During the hearing, you mentioned that your company would 
be likely to lower the list prices of its drugs if the recent proposal 
by the Trump administration to change the current system of rebates was 
extended to the private market.

    If the policy was extended to the private market, how large would 
the list price reductions be relative to the size of the rebates your 
company is currently providing?

    How will this proposal affect how your company sets the list prices 
for new drug products?

    If the proposal is finalized and not extended to the private 
market, will your company make any list price reductions? If so, how 
large would the reductions be relative to the size of the rebates your 
company is currently providing?

    Answer. There has been significant discussion over the past several 
months about proposals to eliminate rebates from Medicare Part D, 
Medicaid, and the commercial market culminating in the administration's 
publication of a proposed rule to ``expressly exclud[e] from safe 
harbor protection under the Anti-Kickback Statute (AKS) rebates on 
prescription drugs paid by manufacturers to pharmacy benefit managers 
(PBMs), Part D plans, and Medicaid managed care organizations. The 
proposal would create a new safe harbor protecting discounts offered to 
patients at the pharmacy counter. Finally, the proposal would create 
new safe harbor protection for fixed fee services arrangements between 
manufacturers and PBMs.''

    AbbVie is encouraged by the goals of the proposed rule to ensure 
manufacturer discounts are reflected in and reduce patient cost sharing 
under Part D. While we believe the rule is an important step in the 
right direction, we also believe more should be done to help reduce the 
out-of-pocket cost burden on Medicare Part D patients.

    As for what the elimination of rebates might mean to the overall 
health care system or pharmaceutical companies, it is premature to 
comment on these items until the administration's rule is finalized, 
implementation timelines are solidified, and there are specific details 
regarding how a new system without rebates will be structured and 
function.

                                 ______
                                 
                Question Submitted by Hon. Maggie Hassan
    Question. In June of 2018, the Medicaid and CHIP Payment and Access 
Commission (MACPAC) unanimously recommended under Recommendation 1.1 in 
their annual report to Congress that Congress remove the statutory 
requirement that manufacturers blend the average manufacturer price 
(AMP) of a brand drug and its authorized generic.\3\
---------------------------------------------------------------------------
    \3\ MACPAC. ``Improving Operations of the Medicaid Drug Rebate 
Program,'' https://www.macpac.gov/wpcontent/uploads/2018/06/Improving-
Operations-of-the-Medicaid-Drug-Rebate-Program.pdf. 

    This requirement created an unintended loophole. Rather than use 
the price of the authorized generic, drug companies can sell its 
authorized generic to a corporate subsidiary at an artificially lower 
price, and use that lower price to bring down the AMP, which in turn 
---------------------------------------------------------------------------
lowers the rebate obligation.

    Does your company engage in this practice? Has your company ever 
engaged in this practice in the past?

    Answer. AbbVie does not engage in this practice and has not engaged 
in this practice in the past. AbbVie only distributes, and has only 
distributed, authorized generic versions of certain of its branded 
products through authorized generic distribution and/or supply 
agreements with third-parties that are wholly unrelated to AbbVie, 
meaning a third-party entity that is not an affiliate or subsidiary of 
AbbVie or otherwise owned by, controlled by, or under common control 
with, in whole or in part, AbbVie. Those agreements are negotiated by 
AbbVie and the third-party at arms-length and in good faith.

                                 ______
                                 
           Questions Submitted by Hon. Catherine Cortez Masto
    Question. As a portion of your revenue, for what percentage of the 
drugs in your portfolio do you offer no rebates? Based on the drugs in 
your pipeline, do you foresee that portion growing? for those drugs is 
your list price equal to your net price?

    Answer. All of AbbVie's on-market medicines have some rebating/
discounting in one or multiple channels and we anticipate all of our 
pipeline medicines will be similar.

    Question. Do you invest more in R&D than you generate in US sales 
revenue? Please include specific figures.

    Answer. AbbVie spent $5.26 billion in research and development in 
2018. AbbVie's research and development spend does not include acquired 
in-process research and development ($424 million in 2018) or money 
invested externally for technology, pharmaceutical compounds or 
acquisitions. For example, AbbVie acquired Pharmacyclics for $20.8 
billion in 2015 and Stemcentrx for $6.4 billion in 2016. In 2018, the 
net revenues for products AbbVie sells in the United States was $21.52 
billion. This includes revenues that are split with Janssen for 
Imbruvica. While AbbVie's U.S net revenues are higher than its research 
and development expense, AbbVie's global net income since it became an 
independent company in 2013 is less than the over $50 billion it has 
invested in that same time period to bring drugs to market.

    Question. Do you invest more in R&D than you spend on marketing and 
administration? What company functions do you consider to be included 
in administration? Please include specific figures.

    Answer. AbbVie spends more on research and development than on 
global sales, marketing, and promotion costs. The global sales, 
marketing, and promotion spend in 2018 across all AbbVie products was 
$4.24 billion. This is less than the $5.26 billion AbbVie spent on 
research and development in 2018. And AbbVie's research and development 
spend does not include acquired inprocess research and development 
($424 million in 2018) or money invested externally for technology, 
pharmaceutical compounds or acquisitions. for example, AbbVie acquired 
Pharmacyclics for $20.8 billion in 2015 and Stemcentrx for $6.4 billion 
in 2016. However, adding the $3.16 billion spent in administration, 
which includes overhead costs such as corporate human resources, 
corporate finance, corporate ethics and compliance, corporate legal, 
and corporate information technology, as well as other expenses such as 
charitable donations, AbbVie spent a total of $7.4 billion in selling, 
marketing, promotion, and administrative expenses (SG&A).

    Question. Do you invest more in R&D than you spend on marketing and 
sales? What company functions do you consider to be included in sales? 
Please include specific figures.

    Answer. AbbVie spends more on research and development than on 
global sales, marketing, and promotion costs. The global sales, 
marketing, and promotion spend in 2018 across all AbbVie products was 
$4.24 billion. This is less than the $5.26 billion AbbVie spent on 
research and development in 2018. And AbbVie's research and development 
spend does not include acquired in-process research and development 
($424 million in 2018) or money invested externally for technology, 
pharmaceutical compounds or acquisitions. for example, AbbVie acquired 
Pharmacyclics for $20.8 billion in 2015 and Stemcentrx for $6.4 billion 
in 2016.

    Sales and marketing includes the cost of AbbVie personnel in the 
sales and marketing field, related overhead, the cost to develop 
marketing and advertising materials, and the cost of placing 
advertisements.

    Question. Why do you advertise for the drugs you manufacture? What 
factors do you consider in choosing which drugs you advertise?

    Answer. Our goal in advertising is to provide those living with the 
conditions that our drugs treat with the best information possible so 
they can have an informed discussion with their health-care provider. 
For many patients DTC ads are an important source of information about 
new medicines, and advertising also plays an important role in raising 
awareness of diseases, removing stigma from certain conditions, and 
encouraging discussions with their health-care providers.

                                 ______
                                 

                               Exhibit 1

                      Grants Donations Report--2014
    (Parentheses represent refunds of previously disclosed payments)
                         Updated as of 3/31/2018
------------------------------------------------------------------------
         Recipient             Payment Amount            Purpose
------------------------------------------------------------------------
100 Black Men of Atlanta,          $20,000.00   Corporate Sponsorship
 Inc.
A and R Educational Group,          $5,500.00   Corporate Sponsorship
 LLC
A Runners Love                      $5,000.00   Corporate Sponsorship
Academia Medica Del                 $(240.57)   Educational Grants
Academia Medica Del                 $(309.06)   Educational Grants
Academia Medica Del                $20,000.00   Educational Grants
Academia Medica Del                $15,000.00   Educational Grants
Academia Medica Del                 $8,800.00   Educational Grants
Academia Medica Del                $10,000.00   Educational Grants
Academia Medica Del                $10,000.00   Educational Grants
Academia Medica Del                $10,000.00   Educational Grants
Academia Medica Del                $10,000.00   Educational Grants
Academia Medica Del                $10,000.00   Educational Grants
Academia Medica Del                 $8,900.00   Educational Grants
Academia Medica Del                 $5,000.00   Educational Grants
Academia Medica Del                 $5,000.00   Educational Grants
Academia Medica Del                $10,000.00   Educational Grants
Academia Medica Del                $10,000.00   Educational Grants
Academia Medica Del                $20,000.00   Educational Grants
Academia Medica Del                $10,000.00   Educational Grants
Academia Medica Del                $10,000.00   Educational Grants
Academia Medica Del                 $5,000.00   Educational Grants
Academia Medica Del                $10,000.00   Educational Grants
Academia Medica Del               $(1,539.53)   Educational Grants
Academia Medica Del                $10,000.00   Educational Grants
Academia Medica Del                $15,000.00   Educational Grants
Academia Medica Del                $15,000.00   Educational Grants
Academia Medica Del                $15,000.00   Educational Grants
Academia Medica Del                $10,000.00   Educational Grants
Academia Medica Del                 $5,000.00   Educational Grants
Academia Medica Del                 $4,000.00   Educational Grants
Academia Medica Del                $10,000.00   Educational Grants
Academia Medica Del                 $5,000.00   Educational Grants
Academia Medica Del                 $5,000.00   Educational Grants
Academia Medica Del                 $5,000.00   Educational Grants
Academia Medica Del                $10,000.00   Educational Grants
Academia Medica Del                $15,000.00   Educational Grants
Academia Medica Del                $10,000.00   Educational Grants
Academia Medica Del                $10,000.00   Educational Grants
Academia Medica Del                $10,000.00   Educational Grants
Academia Medica Del                $20,000.00   Educational Grants
Academia Medica Del                $15,000.00   Educational Grants
Academia Medica Del                 $5,000.00   Educational Grants
Academy of Managed Care            $50,000.00   Corporate Sponsorship
 Pharmacy
Advances in Cosmetic and           $50,000.00   Corporate Sponsorship
 Medical Dermatology, Inc.
Advances in Cosmetic and           $50,000.00   Corporate Sponsorship
 Medical Dermatology, Inc.
Advances in Cosmetic and          $100,000.00   Corporate Sponsorship
 Medical Dermatology, Inc.
Advances in Targeted              $150,000.00   Corporate Sponsorship
 Therapies
Advocate Health and                 $2,500.00   Educational Grants
 Hospitals Corporation
AIDS Drug Assistance                $2,500.00   Corporate Sponsorship
 Programs Advocacy
 Association
AIDS Drug Assistance               $10,000.00   Educational Grants
 Programs Advocacy
 Association
AIDS Drug Assistance                $5,000.00   Corporate Sponsorship
 Programs Advocacy
 Association
AIDS Foundation of Chicago        $125,000.00   Charitable Donations
AIDS Foundation of Chicago          $7,500.00   Charitable Donations
AIDS Project Los Angeles            $5,000.00   Educational Grants
Alaska Kidney Patients              $1,500.00   Patient Support
 Association
Albert Einstein College of         $20,000.00   Educational Grants
 Medicine of Yeshiva
 University
Albert Einstein College of          $5,000.00   Educational Grants
 Medicine of Yeshiva
 University
Albert Einstein College of         $10,000.00   Educational Grants
 Medicine, Division of
 Dermatology Attending
 Association
Albert Einstein Healthcare          $2,500.00   Educational Grants
 Network
Albert Einstein Healthcare          $6,500.00   Corporate Sponsorship
 Network
Alchemy Communications             $50,000.00   Corporate Sponsorship
 Group, LLC
Alliance Foundation for            $75,000.00   Educational Grants
 Continuing Education in
 the Health Professions
Alzheimer's Association            $50,000.00   Corporate Sponsorship
American Academy of               $(8,842.31)   Educational Grants
 Continuing Medical
 Education, Inc.
American Academy of                $25,000.00   Educational Grants
 Continuing Medical
 Education, Inc.
American Academy of                $75,000.00   Corporate Sponsorship
 Dermatology
American Academy of                $50,000.00   Educational Grants
 Dermatology
American Academy of               $100,000.00   Corporate Sponsorship
 Dermatology
American Academy of                $35,000.00   Corporate Sponsorship
 Dermatology
American Academy of                $10,000.00   Charitable Donations
 Neurology Foundation
American Academy of                $45,000.00   Educational Grants
 Physician Assistants
American Academy of                $10,000.00   Educational Grants
 Physician Assistants
American Academy of Urology         $3,000.00   Educational Grants
 Institute--AANI
American Association for           $10,000.00   Educational Grants
 Cancer Research
American Association for           $10,000.00   Educational Grants
 Cancer Research
American Association for           $20,000.00   Charitable Donations
 Laboratory Animal Science
 Foundation
American Association for          $500,000.00   Charitable Donations
 the Study of Liver
 Diseases
American Association for            $7,000.00   Corporate Sponsorship
 the Study of Liver
 Diseases
American Association for          $500,000.00   Charitable Donations
 the Study of Liver
 Diseases
American Association for          $137,500.00   Corporate Sponsorship
 the Study of Liver
 Diseases
American Association of            $25,000.00   Educational Grants
 Clinical Endocrinologists
American Association of            $25,000.00   Educational Grants
 Clinical Endocrinologists
American Association of            $50,000.00   Educational Grants
 Kidney Patients
American Association of            $10,000.00   Patient Support
 Kidney Patients
American Association of            $25,000.00   Corporate Sponsorship
 Pharmaceutical Scientists
American Brain Tumor               $10,000.00   Corporate Sponsorship
 Association
American Chemical Society           $1,000.00   Educational Grants
American College of                 $7,500.00   Educational Grants
 Clinical Pharmacology
American College of               $321,900.00   Corporate Sponsorship
 Endocrinology
American College of               $100,000.00   Corporate Sponsorship
 Gastroenterology
American College of                $20,000.00   Corporate Sponsorship
 Gastroenterology
American College of                $85,000.00   Corporate Sponsorship
 Gastroenterology
American College of                $25,000.00   Charitable Donations
 Laboratory Animal Medicine
American College of                $55,000.00   Corporate Sponsorship
 Physicians Foundation
American College of                $55,000.00   Corporate Sponsorship
 Physicians Foundation
American College of                $55,000.00   Corporate Sponsorship
 Physicians Foundation
American College of               $100,000.00   Corporate Sponsorship
 Rheumatology
American College of               $200,000.00   Fellowships and
 Rheumatology                                    Scholarships
American College of                $75,000.00   Educational Grants
 Rheumatology
American College of                $50,000.00   Educational Grants
 Rheumatology
American College of                $25,000.00   Educational Grants
 Rheumatology
American College of                $25,000.00   Educational Grants
 Rheumatology
American College of               $100,000.00   Corporate Sponsorship
 Rheumatology
American College of             $2,000,000.00   Corporate Sponsorship
 Rheumatology Research and
 Education Foundation
American College of                 $5,000.00   Corporate Sponsorship
 Veterinary Pathologists
American                          $303,800.00   Educational Grants
 Gastroenterological
 Association Institute
American                            $7,000.00   Corporate Sponsorship
 Gastroenterological
 Association Institute
American                          $225,000.00   Educational Grants
 Gastroenterological
 Association Institute
American                          $100,000.00   Corporate Sponsorship
 Gastroenterological
 Association Institute
American Health Resources           $2,000.00   Educational Grants
American Kidney Fund                $5,000.00   Corporate Sponsorship
American Liver Foundation          $10,000.00   Charitable Donations
American Liver Foundation          $10,000.00   Corporate Sponsorship
American Liver Foundation           $5,000.00   Corporate Sponsorship
American Liver Foundation          $10,000.00   Corporate Sponsorship
American Liver Foundation           $6,000.00   Corporate Sponsorship
American Liver Foundation           $2,000.00   Corporate Sponsorship
American Liver Foundation           $5,000.00   Corporate Sponsorship
American Liver Foundation           $5,000.00   Corporate Sponsorship
American Liver Foundation           $5,000.00   Charitable Donations
American Liver Foundation          $10,000.00   Corporate Sponsorship
American Liver Foundation           $2,500.00   Corporate Sponsorship
American Liver Foundation           $5,000.00   Corporate Sponsorship
American Liver Foundation         $127,000.00   Corporate Sponsorship
American Liver Foundation         $106,000.00   Corporate Sponsorship
American Liver Foundation           $5,000.00   Educational Grants
American Liver Foundation           $2,500.00   Corporate Sponsorship
American Medical Group              $6,000.00   Corporate Sponsorship
 Association
American Medical Group              $6,000.00   Corporate Sponsorship
 Association
American Medical Group              $5,050.00   Corporate Sponsorship
 Association
American Medical Group              $5,050.00   Corporate Sponsorship
 Association
American Medical Group              $5,050.00   Corporate Sponsorship
 Association
American Medical Group              $5,050.00   Corporate Sponsorship
 Association
American Medical Group              $5,050.00   Corporate Sponsorship
 Association
American Nephrology Nurses          $2,500.00   Fellowships and
 Association                                     Scholarships
American Neurological              $25,000.00   Educational Grants
 Association
American Pancreatic                $15,000.00   Charitable Donations
 Association
American Pancreatic                $75,000.00   Educational Grants
 Association
American Pancreatic                $35,000.00   Corporate Sponsorship
 Association
American Parkinson Disease          $2,000.00   Educational Grants
 Association, Inc., Georgia
 Chapter
American Physiological              $2,000.00   Educational Grants
 Society
American Skin Association          $15,000.00   Corporate Sponsorship
American Society for                $7,000.00   Corporate Sponsorship
 Gastrointestinal Endoscopy
American Society for Mens          $27,000.00   Corporate Sponsorship
 Health, The
American Society for Mens          $50,000.00   Corporate Sponsorship
 Health, The
American Society for Mens          $60,000.00   Corporate Sponsorship
 Health, The
American Society for               $23,500.00   Corporate Sponsorship
 Microbiology
American Society for               $23,500.00   Corporate Sponsorship
 Microbiology
American Society of                 $5,000.00   Corporate Sponsorship
 Andrology
American Society of                $25,000.00   Educational Grants
 Clinical Oncology
American Society of                 $4,500.00   Corporate Sponsorship
 Clinical Rheumatologists
American Society of                $15,000.00   Educational Grants
 Hematology
American Society of                $75,000.00   Corporate Sponsorship
 Hematology
American Society of                $30,000.00   Educational Grants
 Nephrology
American Statistical                $4,225.00   Corporate Sponsorship
 Association
American Thyroid                   $25,000.00   Educational Grants
 Association, Inc.
American Uroligical                $12,300.00   Corporate Sponsorship
 Association, Northeastern
 Section
American Urological                $20,000.00   Educational Grants
 Association Education and
 Research, Inc.
American Urological                $70,000.00   Educational Grants
 Association Education and
 Research, Inc.
American Urological                $75,000.00   Educational Grants
 Association Education and
 Research, Inc.
American Urological                $50,000.00   Educational Grants
 Association Education and
 Research, Inc.
American Urological                $30,000.00   Educational Grants
 Association Education and
 Research, Inc.
American Urological                $10,000.00   Educational Grants
 Association Education and
 Research, Inc.
American Urological                $10,000.00   Educational Grants
 Association Education and
 Research, Inc.
American Urological                $25,000.00   Educational Grants
 Association Education and
 Research, Inc.
American Urological                $10,000.00   Educational Grants
 Association Education and
 Research, Inc.
American Urological                $25,000.00   Educational Grants
 Association Education and
 Research, Inc.
American Urological                $70,000.00   Corporate Sponsorship
 Association Foundation
American Urological                 $6,000.00   Corporate Sponsorship ,
 Association Inc. Southeast
 Section
American Urological                 $6,000.00   Corporate Sponsorship
 Association, Inc. North
 Central Section
American Urological                $10,000.00   Corporate Sponsorship
 Association, Inc. Western
 Section
American Urological                $10,000.00   Educational Grants
 Association, Mid-Atlantic
 Section, Education Fund,
 Inc.
American Urological                $10,000.00   Educational Grants
 Association, New England
American Urological                 $1,000.00   Corporate Sponsorship
 Association, New York
 Section
American Urological                 $6,000.00   Corporate Sponsorship
 Association, South Central
 Section
Americas Committee for             $10,000.00   Corporate Sponsorship
 Treatment And Research In
 Multiple Sclerosis
Anesthesia Patient Safety          $25,000.00   Charitable Donations
 Foundation
Angel Wings Foundation                $750.00   Corporate Sponsorship
Ann & Robert H. Lurie              $10,000.00   Corporate Sponsorship
 Children's Hospital of
 Chicago
Annenberg Center for Health        $50,000.00   Educational Grants
 Sciences at Eisenhower
Annenberg Center for Health       $125,000.00   Educational Grants
 Sciences at Eisenhower
Annenberg Center for Health        $35,000.00   Educational Grants
 Sciences at Eisenhower
Annenberg Center for Health        $65,000.00   Educational Grants
 Sciences at Eisenhower
Arthritis Foundation               $20,000.00   Corporate Sponsorship
Arthritis Foundation                $8,000.00   Corporate Sponsorship
Arthritis Foundation               $28,500.00   Corporate Sponsorship
Arthritis Foundation               $25,000.00   Corporate Sponsorship
Arthritis Foundation                $5,000.00   Charitable Donations
Arthritis Foundation                $5,000.00   Patient Support
Arthritis Foundation                $5,000.00   Charitable Donations
Arthritis Foundation                $5,000.00   Corporate Sponsorship
 Central, Pennsylvania
 Chapter
Arthritis Foundation New           $10,000.00   Corporate Sponsorship
 England
Arthritis Foundation,             $225,000.00   Corporate Sponsorship
 Alabama Chapter
Arthritis Foundation,             $250,000.00   Corporate Sponsorship
 Alabama Chapter
Arthritis Foundation,             $175,000.00   Corporate Sponsorship
 Alabama Chapter
Arthritis Foundation,              $65,000.00   Patient Support
 Alabama Chapter
Arthritis Foundation,              $17,000.00   Corporate Sponsorship
 Alabama Chapter
Arthritis Foundation,               $2,500.00   Corporate Sponsorship
 Alabama Chapter
Arthritis Foundation,             $259,000.00   Corporate Sponsorship
 Alabama Chapter
Arthritis Foundation,             $175,000.00   Corporate Sponsorship
 Alabama Chapter
Arthritis Foundation,              $35,000.00   Corporate Sponsorship
 Alabama Chapter
Arthritis Foundation,             $250,000.00   Corporate Sponsorship
 Alabama Chapter
Arthritis Foundation, Great         $3,000.00   Patient Support
 Lakes Region
Arthritis Foundation, Great         $2,500.00   Patient Support
 Lakes Region
Arthritis Foundation, Great         $2,500.00   Patient Support
 Lakes Region
Arthritis Foundation, Great        $35,500.00   Corporate Sponsorship
 Lakes Region
Arthritis Foundation, Great        $20,000.00   Charitable Donations
 Lakes Region
Arthritis Foundation, Great         $5,000.00   Charitable Donations
 Lakes Region
Arthritis Foundation, Great        $12,500.00   Charitable Donations
 Lakes Region
Arthritis Foundation, Great         $3,000.00   Charitable Donations
 Lakes Region
Arthritis Foundation, Great         $2,250.00   Patient Support
 Lakes Region
Arthritis Foundation, Great         $2,250.00   Patient Support
 Lakes Region
Arthritis Foundation, Great         $3,000.00   Patient Support
 Lakes Region
Arthritis Foundation, Great         $2,250.00   Patient Support
 Lakes Region
Arthritis Foundation, Great         $2,250.00   Patient Support
 Lakes Region
Arthritis Foundation, Great         $1,000.00   Patient Support
 Lakes Region
Arthritis Foundation, Great        $35,000.00   Corporate Sponsorship
 West Region
Arthritis Foundation, Great        $28,000.00   Corporate Sponsorship
 West Region
Arthritis Foundation, Great        $10,000.00   Charitable Donations
 West Region
Arthritis Foundation,              $21,000.00   Corporate Sponsorship
 Massachusetts Chapter
Arthritis Foundation,               $1,853.94   Patient Support
 Massachusetts Chapter
Arthritis Foundation,               $3,000.00   Corporate Sponsorship
 Massachusetts Chapter
Arthritis Foundation,               $3,000.00   Corporate Sponsorship
 Massachusetts Chapter
Arthritis Foundation, Mid          $15,000.00   Corporate Sponsorship
 Atlantic Region
Arthritis Foundation, Mid           $1,500.00   Educational Grants
 Atlantic Region
Arthritis Foundation, Mid           $1,000.00   Patient Support
 Atlantic Region
Arthritis Foundation, South        $14,000.00   Corporate Sponsorship
 Texas Chapter
Arthritis Foundation, South         $2,500.00   Charitable Donations
 Texas Chapter
Arthritis Foundation,              $65,000.00   Corporate Sponsorship
 Southern California
 Chapter
Arthritis Foundation,               $2,500.00   Charitable Donations
 Southern California
 Chapter
Arthritis Foundation,               $2,500.00   Charitable Donations
 Southern California
 Chapter
Arthritis Foundation,               $5,000.00   Corporate Sponsorship
 Southern California
 Chapter
Arthritis Foundation,               $7,000.00   Corporate Sponsorship
 Wisconsin Chapter
Arthritis Patient Services         $10,000.00   Educational Grants
Arthritis Patient Services         $25,000.00   Educational Grants
ASCO Cancer Foundation             $50,000.00   Charitable Donations
ASCO Cancer Foundation             $40,000.00   Fellowships and
                                                 Scholarships
ASCO Cancer Foundation             $28,000.00   Educational Grants
Asociacion de Reumatologos         $15,000.00   Corporate Sponsorship
 de Puerto Rico
Asociacion Nacional de              $4,000.00   Corporate Sponsorship
 Tecnicos de Farmacia, Inc.
Asociacion Puertorriquena           $1,200.00   Corporate Sponsorship
 de Ayuda al Paciente de
 Psoriasis
Association of Dermatology          $7,500.00   Corporate Sponsorship
 Administrators And
 Managers
Association of Nurses in           $15,000.00   Educational Grants
 AIDS Care, Chicago Chapter
Association of Physicians           $2,500.00   Corporate Sponsorship
 of Pakistani-Descent of
 North America
Balm In Gilead Inc.                $75,000.00   Corporate Sponsorship
Baylor College of Medicine          $5,000.00   Educational Grants
Baylor University Medical          $67,716.00   Educational Grants
 Center
Baylor University Medical          $29,340.00   Educational Grants
 Center
Beth Israel Deaconess              $50,000.00   Fellowships and
 Department of Medicine                          Scholarships
 Foundation
Beth Israel Deaconess             $(1,948.24)   Educational Grants
 Medical Center
Beth Israel Deaconess              $40,000.00   Fellowships and
 Medical Center                                  Scholarships
Billings Clinic                     $5,000.00   Corporate Sponsorship
Bioconnections, LLC                $15,000.00   Corporate Sponsorship
Biophysical Society                 $2,500.00   Educational Grants
Blank Children's Hospital           $2,500.00   Corporate Sponsorship
Board of Regents of the             $5,000.00   Educational Grants
 University of Wisconsin
 System
Board of Trustees of the            $1,500.00   Educational Grants
 University of Illinois
Board of Trustees of The           $40,000.00   Fellowships and
 University of Illinois,                         Scholarships
 The
Board of Trustees of The           $30,000.00   Fellowships and
 University of Illinois,                         Scholarships
 The
Boomer Esiason Foundation           $1,200.00   Corporate Sponsorship
Boomer Esiason Foundation         $100,000.00   Educational Grants
Boomer Esiason Foundation          $75,000.00   Charitable Donations
Boomer Esiason Foundation         $400,000.00   Corporate Sponsorship
Boomer Esiason Foundation          $25,000.00   Corporate Sponsorship
Boomer Esiason Foundation         $400,000.00   Corporate Sponsorship
Boston Society, Inc.                $4,000.00   Corporate Sponsorship
Boston Society, Inc.                $4,000.00   Corporate Sponsorship
Boston University School of       $124,943.00   Educational Grants
 Medicine
Brigham and Women's              $(50,000.00)   Fellowships and
 Hospital, Inc.                                  Scholarships
Brigham and Women's                $50,000.00   Fellowships and
 Hospital, Inc.                                  Scholarships
California Rheumatology            $30,000.00   Corporate Sponsorship
 Alliance
California Separation              $60,000.00   Corporate Sponsorship
 Science Society
California Society of               $3,000.00   Corporate Sponsorship
 Health System Pharmacists
California Society of               $5,000.00   Corporate Sponsorship
 Health System Pharmacists
California Society of               $3,000.00   Corporate Sponsorship
 Health System Pharmacists
Campaign for Public Health         $10,000.00   Charitable Donations
 Foundation
Cancer and Leukemia Group B        $20,000.00   Educational Grants
 Foundation
Cancer Molecular                    $5,000.00   Educational Grants
 Therapeutics
Case Western Reserve               $25,000.00   Educational Grants
 University
Cedars-Sinai Medical Center        $40,000.00   Educational Grants
Cedars-Sinai Medical Center        $10,000.00   Educational Grants
Cedars-Sinai Medical Center        $40,000.00   Fellowships and
                                                 Scholarships
Central Florida Pharmacy           $25,000.00   Educational Grants
 Council, Inc.
Central Ohio Parkinson             $20,000.00   Educational Grants
 Society DBA National
 Parkinson Foundation
 Central and Southeast Ohio
Chelsea Hutchinson                  $2,500.00   Corporate Sponsorship
 Foundation The
Children and Arthritis,             $5,000.00   Charitable Donations
 Inc.
Children's Digestive Health        $40,000.00   Fellowships and
 and Nutrition Foundation                        Scholarships
Children's Digestive Health        $25,000.00   Educational Grants
 and Nutrition Foundation
Children's Digestive Health        $40,000.00   Fellowships and
 and Nutrition Foundation                        Scholarships
Children's Digestive Health        $10,000.00   Corporate Sponsorship
 and Nutrition Foundation
Children's Hospital Medical        $20,000.00   Corporate Sponsorship
 Center
Children's Hospital Medical        $40,000.00   Fellowships and
 Center                                          Scholarships
Children's Hospital Medical        $20,000.00   Corporate Sponsorship
 Center
Children's Oncology                 $5,500.00   Corporate Sponsorship
 Services Inc.
Chimp Haven                        $50,000.00   Charitable Donations
Chris Dudley Foundation             $5,000.00   Corporate Sponsorship
Chronic Liver Disease             $211,000.00   Educational Grants
 Foundation
Chronic Liver Disease             $211,670.00   Educational Grants
 Foundation
Chronic Liver Disease           $1,300,000.00   Educational Grants
 Foundation
Chronic Liver Disease               $7,500.00   Corporate Sponsorship
 Foundation
Cleveland Clinic                  $(1,340.00)   Educational Grants
Cleveland Clinic                   $10,000.00   Educational Grants
 Educational Foundation,
 The
Cleveland Clinic                   $25,000.00   Educational Grants
 Educational Foundation,
 The
Cleveland Clinic                   $75,000.00   Educational Grants
 Educational Foundation,
 The
Cleveland Clinic                    $4,500.00   Educational Grants
 Educational Foundation,
 The
Cleveland Clinic                  $(2,033.31)   Educational Grants
 Educational Foundation,
 The
Cleveland Clinic                   $75,000.00   Educational Grants
 Educational Foundation,
 The
Cleveland Clinic                   $15,000.00   Educational Grants
 Educational Foundation,
 The
Cleveland Clinic                  $385,000.00   Educational Grants
 Educational Foundation,
 The
Cleveland Clinic                  $132,000.00   Educational Grants
 Educational Foundation,
 The
Cleveland Clinic                   $15,000.00   Educational Grants
 Educational Foundation,
 The
Cleveland Clinic                    $5,000.00   Educational Grants
 Educational Foundation,
 The
Cleveland Clinic                  $(2,638.82)   Educational Grants
 Educational Foundation,
 The
Cleveland Clinic                   $75,000.00   Educational Grants
 Educational Foundation,
 The
Cleveland Clinic                    $5,000.00   Educational Grants
 Educational Foundation,
 The
Cleveland Clinic Foundation        $50,000.00   Fellowships and
                                                 Scholarships
Cleveland Clinic Foundation        $50,000.00   Fellowships and
                                                 Scholarships
Clinical Care Options, LLC         $75,000.00   Educational Grants
Clinical Care Options, LLC        $150,000.00   Educational Grants
Clinical Care Options, LLC         $50,000.00   Educational Grants
Clinical Care Options, LLC         $25,000.00   Educational Grants
Clinical Care Options, LLC        $100,000.00   Educational Grants
Clinical Care Options, LLC        $209,000.00   Educational Grants
CME Incite, LLC                 $(175,000.00)   Educational Grants
Coalition for Prevention of         $5,000.00   Corporate Sponsorship
 Colorectal Cancer in
 Puerto Rico
Coalition on Positive             $125,000.00   Patient Support
 Health Empowerment
Colegio Medicos-Cirujanos          $20,000.00   Educational Grants
 P.R
Com & Co Sarl                       $3,550.00   Corporate Sponsorship
Community Health                   $10,000.00   Corporate Sponsorship
Community Initiatives              $10,000.00   Corporate Sponsorship
Community Liver Alliance            $3,000.00   Corporate Sponsorship
Community Liver Alliance            $1,000.00   Corporate Sponsorship
Community Liver Alliance            $5,000.00   Corporate Sponsorship
Community Liver Alliance          $150,000.00   Educational Grants
Complete Conference                $50,000.00   Educational Grants
 Management
Complete Conference                $75,000.00   Educational Grants
 Management
Complete Conference              $(75,000.00)   Educational Grants
 Management
Complete Conference              $(75,000.00)   Educational Grants
 Management
Consortium of Multiple             $25,000.00   Educational Grants
 Sclerosis Centers
Continuing Educational              $(703.13)   Educational Grants
 Alliance, LLC
Continuing Educational            $362,500.00   Educational Grants
 Alliance, LLC
Continuing Educational              $(210.66)   Educational Grants
 Alliance, LLC
Continuing Educational              $(258.18)   Educational Grants
 Alliance, LLC
Continuing Educational            $(1,696.48)   Educational Grants
 Alliance, LLC
Continuing Medical                 $85,000.00   Educational Grants
 Education Outfitters, LLC
Continuous Renal                   $10,000.00   Educational Grants
 Replacement Therapies,
 Inc. (CRRT)
Cornell University, Weill           $5,000.00   Educational Grants
 Medical College
Cornerstone Health, Inc.          $(3,664.00)   Educational Grants
Cornerstone Health, Inc.          $200,000.00   Educational Grants
Cornerstone Health, Inc.          $175,000.00   Educational Grants
Cornerstone Health, Inc.           $40,000.00   Educational Grants
Cornerstone Health, Inc.          $100,000.00    Educational Grants
Creighton University                $2,220.00   Charitable Donations
Crohn's and Colitis                 $2,500.00   Corporate Sponsorship
 Foundation of America
Crohn's and Colitis                $22,500.00   Corporate Sponsorship
 Foundation of America
Crohn's and Colitis               $350,000.00   Corporate Sponsorship
 Foundation of America
Crohn's and Colitis               $100,000.00   Corporate Sponsorship
 Foundation of America
Crohn's and Colitis                $20,000.00   Corporate Sponsorship
 Foundation of America
Crohn's and Colitis                 $9,000.00   Educational Grants
 Foundation of America
Crohn's and Colitis                 $6,000.00   Patient Support
 Foundation of America
Crohn's and Colitis                $80,000.00   Corporate Sponsorship
 Foundation of America
Crohn's and Colitis                 $9,000.00   Patient Support
 Foundation of America
Crohn's and Colitis                 $6,200.00   Patient Support
 Foundation of America
Crohn's and Colitis                 $4,000.00   Patient Support
 Foundation of America
Crohn's and Colitis               $(3,095.00)   Educational Grants
 Foundation of America
Crohn's and Colitis                $65,000.00   Educational Grants
 Foundation of America
Crohn's and Colitis                 $3,000.00   Educational Grants
 Foundation of America
Crohn's and Colitis                $10,000.00   Patient Support
 Foundation of America
Crohn's and Colitis                 $1,000.00   Corporate Sponsorship
 Foundation of America
Crohn's and Colitis                $25,000.00   Charitable Donations
 Foundation of America
Crohn's and Colitis                 $2,000.00   Corporate Sponsorship
 Foundation of America
Crohn's and Colitis               $100,000.00   Educational Grants
 Foundation of America
Crohn's and Colitis                 $8,000.00   Educational Grants
 Foundation of America
Crohn's and Colitis                 $2,000.00   Corporate Sponsorship
 Foundation of America
Crohn's and Colitis                 $5,000.00   Corporate Sponsorship
 Foundation of America
Crohn's and Colitis                 $2,500.00   Corporate Sponsorship
 Foundation of America
Crohn's and Colitis                 $3,500.00   Patient Support
 Foundation of America
Crohn's and Colitis               $100,000.00   Fellowships and
 Foundation of America                           Scholarships
Crohn's and Colitis                 $3,000.00   Patient Support
 Foundation of America
Crohn's and Colitis                 $5,000.00   Corporate Sponsorship
 Foundation of America
Crohn's and Colitis                 $1,500.00   Corporate Sponsorship
 Foundation of America
Crohn's and Colitis                $10,000.00   Educational Grants
 Foundation of America
Crohn's and Colitis                $65,000.00   Educational Grants
 Foundation of America
Crohn's and Colitis                $25,000.00   Charitable Donations
 Foundation of America
Crohn's and Colitis               $100,000.00   Educational Grants
 Foundation of America
Curatio CME Institute           $(100,000.00)   Educational Grants
Cystic Fibrosis--Reaching          $25,000.00   Charitable Donations
 Out Foundation
Cystic Fibrosis Foundation--        $5,000.00   Corporate Sponsorship
 Albany
Cystic Fibrosis Foundation--        $3,500.00   Corporate Sponsorship
 Albany
Cystic Fibrosis Foundation--        $1,000.00   Corporate Sponsorship
 Albany
Cystic Fibrosis Foundation--      $100,000.00   Charitable Donations
 Albany
Cystic Fibrosis Foundation--        $2,000.00   Corporate Sponsorship
 Albany
Cystic Fibrosis Foundation--        $5,000.00   Corporate Sponsorship
 Albany
Cystic Fibrosis Foundation--       $10,000.00   Corporate Sponsorship
 Albany
Cystic Fibrosis Foundation--        $4,000.00   Corporate Sponsorship
 Albany
Cystic Fibrosis Foundation--       $10,000.00   Corporate Sponsorship
 Albany
Cystic Fibrosis Foundation--        $2,000.00   Corporate Sponsorship
 Albany
Cystic Fibrosis Foundation--        $3,000.00   Corporate Sponsorship
 Albany
Cystic Fibrosis Foundation--        $1,000.00   Corporate Sponsorship
 Albany
Cystic Fibrosis Foundation--        $2,500.00   Corporate Sponsorship
 Albany
Cystic Fibrosis Foundation--        $1,500.00   Corporate Sponsorship
 Albany
Cystic Fibrosis Foundation--        $2,500.00   Corporate Sponsorship
 Albany
Cystic Fibrosis Foundation--        $2,500.00   Corporate Sponsorship
 Albany
Cystic Fibrosis Foundation--       $25,000.00   Corporate Sponsorship
 Albany
Cystic Fibrosis Foundation--        $1,500.00   Corporate Sponsorship
 Albany
Cystic Fibrosis Foundation--        $1,500.00   Corporate Sponsorship
 Albany
Cystic Fibrosis Foundation--        $1,000.00   Corporate Sponsorship
 Albany
Cystic Fibrosis Foundation--        $1,000.00   Corporate Sponsorship
 Albany
Cystic Fibrosis Foundation--       $15,000.00   Corporate Sponsorship
 Albany
Cystic Fibrosis Research,             $500.00   Corporate Sponsorship
 Inc.
Cystic Fibrosis Research,          $10,000.00   Educational Grants
 Inc.
Cystic Fibrosis Research,           $9,000.00   Patient Support
 Inc.
Cystic Fibrosis Research,           $5,000.00   Corporate Sponsorship
 Inc.
Cystic Fibrosis Research,           $5,000.00   Corporate Sponsorship
 Inc.
Cystic Fibrosis Research,          $15,000.00   Charitable Donations
 Inc.
Cystic Fibrosis Research,          $10,000.00   Corporate Sponsorship
 Inc.
Dade County Medical                $10,000.00   Educational Grants
 Association
Dallas fort Worth Business          $5,000.00   Corporate Sponsorship
 Group on Health
Davis Phinney Foundation           $30,000.00   Educational Grants
Davis Phinney Foundation           $75,000.00   Educational Grants
Davis Phinney Foundation           $15,000.00   Educational Grants
Davis Phinney Foundation           $30,000.00   Educational Grants
Decatur General Hospital            $2,500.00   Corporate Sponsorship
 Foundation
Dermatology Education              $15,000.00   Corporate Sponsorship
 Foundation
Dermatology Foundation             $50,000.00   Corporate Sponsorship
Diversity And Leadership            $5,000.00   Corporate Sponsorship
 Inc.
Duke University                     $6,550.00   Educational Grants
Duke University                   $250,000.00   Educational Grants
Duke University                   $150,000.00   Educational Grants
Duke University                    $50,000.00   Fellowships and
                                                 Scholarships
Duke University                   $(3,061.96)   Educational Grants
Educational Review Systems         $10,000.00   Educational Grants
Elizabeth Glaser Pediatric         $10,000.00   Charitable Donations
 AIDS Foundation
Elsevier, Inc.                     $70,000.00   Educational Grants
Employers Health Colition           $4,000.00   Corporate Sponsorship
 Inc.
Endocrine Education, Inc           $25,000.00   Educational Grants
Endocrine Nurses Society            $4,000.00   Corporate Sponsorship
Endocrine Society, The             $25,000.00   Educational Grants
Endocrine Society, The            $150,000.00   Educational Grants
Endometriosis Association          $10,000.00   Charitable Donations
Engineering Conferences             $1,000.00   Educational Grants
 International
Enzyme Mechanisms                   $1,500.00   Educational Grants
 Conference
Epilepsy Foundation                $80,000.00   Charitable Donations
ERA-Eurocongress, Ltd.             $25,000.00   Corporate Sponsorship
ERA-Eurocongress, Ltd.             $15,000.00   Corporate Sponsorship
Escuela De Medicina De             $10,000.00   Educational Grants
 Ponce
Escuela De Medicina De             $10,000.00   Educational Grants
 Ponce
European Society for              $250,000.00   Corporate Sponsorship
 Dermatological Research
European Society for               $10,000.00   Corporate Sponsorship
 Medical Oncology
Excel Continuing Education          $8,225.00   Educational Grants
Excellence in Rheumatology        $100,000.00   Corporate Sponsorship
 Education, LLC
Facing Our Risk of Cancer          $25,000.00   Charitable Donations
 Empowerement
Facing Our Risk of Cancer           $5,000.00   Corporate Sponsorship
 Empowerement (FORCE)
Federation of American              $1,500.00   Educational Grants
 Societies for Experimental
 Biology
Federation of American              $1,500.00   Educational Grants
 Societies for Experimental
 Biology
Federation of American              $5,000.00   Corporate Sponsorship
 Societies for Experimental
 Biology
Federation of Clinical             $20,000.00   Educational Grants
 Immunology Societies
Federation of Clinical             $15,000.00   Educational Grants
 Immunology Societies
Federation of Clinical             $20,000.00   Educational Grants
 Immunology Societies
Florida Academy of                  $8,300.00   Educational Grants
 Physician Assistants
Florida Health Care                 $1,500.00   Corporate Sponsorship
 Coalition
Foundation for Anesthesia          $20,000.00   Fellowships and
 Education and Research                          Scholarships
Foundation for Biomedical         $120,000.00   Charitable Donations
 Research
Foundation for Indiana              $2,220.00   Charitable Donations
 University of Pennsylvania
Foundation for Indiana              $2,220.00   Charitable Donations
 University of Pennsylvania
Foundation for Men's               $50,000.00   Corporate Sponsorship
 Health, Inc
Foundation for the National       $400,000.00   Corporate Sponsorship
 Institutes of Health
Friends of Prentice                $10,000.00   Corporate Sponsorship
Friends of the St. Louis           $50,000.00   Corporate Sponsorship
 University Liver Center
Fundacion Puertorriquena De         $7,500.00   Educational Grants
 Pacientes Con
 Endometriosis
Gastrointestinal Health           $150,000.00   Educational Grants
 Foundation, Inc.
Gastrointestinal Health            $50,000.00   Educational Grants
 Foundation, Inc.
Gastrointestinal Health            $75,000.00   Corporate Sponsorship
 Foundation, Inc.
Gastro-Intestinal Research         $15,000.00   Charitable Donations
 Foundation
Gastro-Intestinal Research          $1,000.00   Corporate Sponsorship
 Foundation
Gastro-Intestinal Research          $6,600.00   Corporate Sponsorship
 Foundation
Gastro-Intestinal Research          $1,500.00   Corporate Sponsorship
 Foundation
Gateway for Cancer Research         $6,000.00   Charitable Donations
Gay City Health Project            $10,000.00   Charitable Donations
Georgia ObGyn Society               $2,500.00   Corporate Sponsorship
Georgia Prostate Cancer             $4,000.00   Patient Support
 Coalition, The
Georgia Society of                  $3,000.00   Corporate Sponsorship
 Dermatology and
 Dermatologic Surgery
Gilda's Club Chicago               $10,000.00   Charitable Donations
Gilda's Club New York City         $50,000.00   Charitable Donations
Globalization of                   $10,000.00   Corporate Sponsorship
 Pharmaceutics Education
 Network
Gordon Research Conferences         $1,500.00   Educational Grants
Gordon Research Conferences         $1,500.00   Educational Grants
Gordon Research Conferences         $1,500.00   Educational Grants
Gordon Research Conferences         $1,500.00   Educational Grants
Gordon Research Conferences         $1,500.00   Educational Grants
Gordon Research Conferences         $1,500.00   Educational Grants
Gordon Research Conferences         $1,500.00   Educational Grants
Gordon Research Conferences         $1,500.00   Educational Grants
Gordon Research Conferences         $1,500.00   Educational Grants
Gordon Research Conferences         $1,500.00   Educational Grants
Gordon Research Conferences         $2,000.00   Educational Grants
Grupo de Apoyo de Ninos y           $3,000.00   Corporate Sponsorship
 Adolescentes con
 Reumatologia
Gynecologic Oncology Group,        $25,000.00   Educational Grants
 The
$7                                 $23,000.00   Educational Grants
Haymarket Center-Health             $5,000.00   Educational Grants
 Education
Haymarket Medical Education       $243,190.00   Educational Grants
Health Sciences Foundation          $2,500.00   Educational Grants
 dba South East AHEC
Healthcare Businesswomen's          $5,000.00   Corporate Sponsorship
 Association, Inc.
Healthcare Financial               $50,000.00   Corporate Sponsorship
 Management Association
Hep C Connection                   $50,000.00   Educational Grants
Hep C Connection                   $40,000.00   Patient Support
Hep C Connection                    $5,000.00   Corporate Sponsorship
Hepatitis C Association            $45,000.00   Educational Grants
Hepatitis C Mentor and             $10,000.00   Patient Support
 Support Group, The
Hepatitis Education Project       $100,000.00   Charitable Donations
HIV Treaters Medical               $10,000.00   Educational Grants
 Association of Puerto Rico
Hope Foundation, The               $10,000.00   Educational Grants
Housing Works, Inc.                $10,000.00   Charitable Donations
Howard Brown Health Center         $25,000.00   Corporate Sponsorship
Howard Center Inc.                 $10,000.00   Charitable Donations
Howard University Hospital         $10,000.00   Educational Grants
Hubbard Street Dance               $10,000.00   Educational Grants
 Chicago
Human Growth Foundation             $2,000.00   Corporate Sponsorship
IDSA Education and Research        $10,000.00   Fellowships and
 Foundation                                      Scholarships
Imedex, LLC                        $20,000.00   Educational Grants
Imedex, LLC                        $75,000.00   Educational Grants
Imedex, LLC                        $15,000.00   Educational Grants
Imedex, LLC                        $25,000.00   Educational Grants
Imedex, LLC                        $60,000.00   Educational Grants
Impact Education, LLC             $125,000.00   Educational Grants
Indiana Chamber of Commerce         $2,500.00   Corporate Sponsorship
Indiana Chamber of Commerce         $1,500.00   Corporate Sponsorship
Indiana University                  $2,500.00   Fellowships and
                                                 Scholarships
Induniv Research                    $2,000.00   Corporate Sponsorship
Infectious Diseases Society        $35,000.00   Educational Grants
 of America
Inflammatory Bowel Disease        $300,000.00   Educational Grants
 Support Foundation
Inflammatory Bowel Disease         $50,000.00   Educational Grants
 Support Foundation
Inflammatory Bowel Disease        $200,000.00   Educational Grants
 Support Foundation
Inflammatory Bowel Disease        $200,000.00   Educational Grants
 Support Foundation
Innovation Development            $250,000.00   Corporate Sponsorship
 Institute, Inc.
Institute for Medical and          $10,000.00   Educational Grants
 Nursing Education, Inc.
Integrated Benefits                $35,000.00   Corporate Sponsorship
 Institute, Inc.
Integrated Medical                 $50,000.00   Charitable Donations
 Foundation
Integrated Medical                  $5,000.00   Corporate Sponsorship
 Foundation
Integrated Medical                 $35,000.00   Charitable Donations
 Foundation
Interfaith House                    $2,000.00   Charitable Donations
Intermountain Dermatology          $20,000.00   Educational Grants
 Society
International AIDS Society--      $100,000.00   Educational Grants
 USA
International AIDS Society--      $100,000.00   Educational Grants
 USA
International AIDS Society--       $75,000.00   Educational Grants
 USA
International Alliance for          $3,000.00   Educational Grants
 Biologicals
International Association          $10,000.00   Educational Grants
 of Physicians in AIDS Care
International Association          $25,000.00   Educational Grants
 of Physicians in AIDS Care
International Chemical              $2,000.00   Educational Grants
 Biology Society
International Pelvic Pain           $7,500.00   Educational Grants
 Society
International Psoriasis           $100,000.00   Corporate Sponsorship
 Council, The
International Psoriasis            $50,000.00   Corporate Sponsorship
 Council, The
International Society for           $5,000.00   Educational Grants
 Antiviral Research
International Society for          $10,000.00   Corporate Sponsorship
 Medical Publication
 Professionals
International Society for           $3,000.00   Educational Grants
 the Study of Xenobiotics
International Society of           $50,000.00   Charitable Donations
 Nephrology
International Society of           $40,000.00   Charitable Donations
 Nephrology
International Society of          $175,000.00   Corporate Sponsorship
 Nephrology
Jefferson Medical College           $3,000.00   Corporate Sponsorship
 at Thomas Jefferson
 University
Jefferson Medical College          $30,000.00   Educational Grants
 at Thomas Jefferson
 University
Jefferson Medical College           $5,000.00   Educational Grants
 at Thomas Jefferson
 University
John Hopkins University           $(1,706.15)   Educational Grants
 School of Medicine
Johns Hopkins University          $225,000.00   Educational Grants
 School of Medicine
Johns Hopkins University           $25,000.00   Educational Grants
 School of Medicine
Johns Hopkins University         $(60,000.00)   Educational Grants
 School of Medicine
Johns Hopkins University           $30,000.00   Educational Grants
 School of Medicine
Johns Hopkins University           $50,000.00   Fellowships and
 School of Medicine                              Scholarships
Johns Hopkins University           $95,000.00   Educational Grants
 School of Medicine
Johns Hopkins University            $5,000.00   Educational Grants
 School of Medicine
Joint Township District             $4,064.00   Patient Support
 Memorial Hospital
Joint Township District           $(1,508.00)   Patient Support
 Memorial Hospital
JWC Covenant, Inc.                 $35,000.00   Educational Grants
Kansas University                  $25,000.00   Educational Grants
 Neurological Foundation
Kansas University                  $35,000.00   Educational Grants
 Neurological Foundation
Kelsey Research Foundation         $40,000.00   Fellowships and
                                                 Scholarships
Kenes International Ltd.           $35,000.00   Corporate Sponsorship
Kidney Disease Improving           $40,128.00   Corporate Sponsorship
 Global Outcomes
KnowledgePoint360 Group,           $94,785.30   Corporate Sponsorship
 LLC
Laboratorio Clinico Toledo          $2,460.00   Patient Support
Laboratorio Clinico Toledo            $795.00   Patient Support
Laboratorio Clinico Toledo            $345.00   Patient Support
Laboratorio Clinico Toledo          $2,760.00   Patient Support
Laboratorio Clinico Toledo          $2,145.00   Patient Support
Laboratorio Clinico Toledo            $615.00   Patient Support
Laboratorio Clinico Toledo          $2,160.00   Patient Support
Laboratorio Clinico Toledo          $2,115.00   Patient Support
Laboratorio Clinico Toledo          $1,380.00   Patient Support
Laboratorio Clinico Toledo          $4,260.00   Patient Support
Laboratorio Clinico Toledo          $2,070.00   Patient Support
Laboratorio Clinico Toledo          $1,650.00   Patient Support
Laboratorio Clinico Toledo          $1,500.00   Patient Support
Laboratorio Clinico Toledo          $1,395.00   Patient Support
Laboratorio Clinico Toledo          $1,380.00   Patient Support
Laboratorio Clinico Toledo          $1,290.00   Patient Support
Laboratorio Clinico Toledo          $1,200.00   Patient Support
Laboratorio Clinico Toledo            $996.00   Patient Support
Laboratorio Clinico Toledo            $825.00   Patient Support
Laboratorio Clinico Toledo            $804.00   Patient Support
Laboratorio Clinico Toledo          $4,455.00   Patient Support
Laboratorio Clinico Toledo            $945.00   Patient Support
Laboratorio Clinico Toledo            $690.00   Patient Support
Laboratorio Clinico Toledo          $1,530.00   Patient Support
Laboratorio Clinico Toledo          $1,335.00   Patient Support
Laboratorio Clinico Toledo          $1,065.00   Patient Support
Laboratorio Clinico Toledo            $975.00   Patient Support
Laboratorio Clinico Toledo          $2,250.00   Patient Support
Laboratorio Clinico Toledo          $2,250.00   Patient Support
Laboratorio Clinico Toledo            $825.00   Patient Support
Laboratorio Clinico Toledo            $720.00   Patient Support
Laboratorio Clinico Toledo            $510.00   Patient Support
Laboratorio Clinico Toledo          $1,500.00   Patient Support
Laboratorio Clinico Toledo          $1,500.00   Patient Support
Laboratorio Clinico Toledo          $1,500.00   Patient Support
Laboratorio Clinico Toledo          $1,365.00   Patient Support
Laboratorio Clinico Toledo          $1,185.00   Patient Support
Laboratorio Clinico Toledo          $1,125.00   Patient Support
Laboratorio Clinico Toledo          $1,110.00   Patient Support
Laboratorio Clinico Toledo          $1,095.00   Patient Support
Laboratorio Clinico Toledo            $855.00   Patient Support
Laboratorio Clinico Toledo            $765.00   Patient Support
Laboratorio Clinico Toledo            $750.00   Patient Support
Laboratorio Clinico Toledo            $525.00   Patient Support
Laboratorio Clinico Toledo          $1,230.00   Patient Support
Laboratorio Clinico Toledo          $1,185.00   Patient Support
Laboratorio Clinico Toledo          $1,110.00   Patient Support
Laboratorio Clinico Toledo            $960.00   Patient Support
Laboratorio Clinico Toledo            $300.00   Patient Support
Laboratorio Clinico Toledo          $1,500.00   Patient Support
Laboratorio Clinico Toledo          $1,230.00   Patient Support
Laboratorio Clinico Toledo            $720.00   Patient Support
Laboratorio Clinico Toledo            $570.00   Patient Support
Laboratorio Clinico Toledo          $1,035.00   Patient Support
Laboratorio Clinico Toledo            $990.00   Patient Support
Laboratorio Clinico Toledo            $810.00   Patient Support
Laboratorio Clinico Toledo            $705.00   Patient Support
Laboratorio Clinico Toledo            $705.00   Patient Support
Laboratorio Clinico Toledo          $1,095.00   Patient Support
Laboratorio Clinico Toledo            $750.00   Patient Support
Laboratorio Clinico Toledo            $675.00   Patient Support
Laboratorio Clinico Toledo            $255.00   Patient Support
Laboratorio Clinico Toledo          $1,470.00   Patient Support
Laboratorio Clinico Toledo          $1,275.00   Patient Support
Laboratorio Clinico Toledo          $1,230.00   Patient Support
Laboratorio Clinico Toledo          $1,095.00   Patient Support
Laboratorio Clinico Toledo            $900.00   Patient Support
Laboratorio Clinico Toledo            $585.00   Patient Support
Laboratorio Clinico Toledo          $1,890.00   Patient Support
Laboratorio Clinico Toledo          $1,380.00   Patient Support
Laboratorio Clinico Toledo          $1,185.00   Patient Support
Laboratorio Clinico Toledo            $975.00   Patient Support
Laboratorio Clinico Toledo          $2,190.00   Patient Support
Lake County Haven                   $5,000.00   Corporate Sponsorship
Large Urology Group                 66,400.00   Corporate Sponsorship
 Practice Association
Latinos Salud, Inc.                 $7,500.00   Charitable Donations
Legacy Counseling Center            $7,500.00   Charitable Donations
Leukemia and Lymphoma               $2,500.00   Educational Grants
 Society, The
Leukemia Research                   $2,500.00   Charitable Donations
 Foundation
Life Sciences Foundation           $30,000.00   Charitable Donations
Life Sciences Foundation           $30,000.00   Charitable Donations
Life Sciences Foundation           $30,000.00   Charitable Donations
Linking Leaders, LLC               $20,000.00   Corporate Sponsorship
Liver Institute and                $50,000.00   Educational Grants
 Foundation for Education
 and Research
Living Beyond Breast Cancer        $10,000.00   Corporate Sponsorship
Living Beyond Breast Cancer         $5,000.00   Corporate Sponsorship
Living Beyond Breast Cancer         $5,000.00   Corporate Sponsorship
Loma Linda University               $1,200.00   Fellowships and
 School of Medicine                              Scholarships
Malecare                           $12,000.00   Patient Support
Marsha Rivkin Center for            $2,500.00   Educational Grants
 Ovarian Cancer Research
Massachusetts General              $25,000.00   Fellowships and
 Hospital                                        Scholarships
Massachusetts Institute of          $2,220.00   Charitable Donations
 Technology
Massachusetts Institute of          $2,220.00   Charitable Donations
 Technology
Massachusetts Institute of          $5,000.00   Educational Grants
 Technology
Massachusetts Prostate              $5,000.00   Educational Grants
 Cancer Coalition, Inc.
May We Help                         $3,000.00   Corporate Sponsorship
May We Help                         $2,500.00   Corporate Sponsorship
May We Help                         $2,500.00   Corporate Sponsorship
Mayo Clinic                        $10,000.00   Educational Grants
Medical College of                 $10,000.00   Educational Grants
 Wisconsin
Medical College of                 $15,000.00   Educational Grants
 Wisconsin
Medical Learning Institute         $90,000.00   Educational Grants
Medical Learning Institute       $(90,000.00)   Educational Grants
Medical Learning Institute         $75,000.00   Educational Grants
Medicinal and Bioorganic            $5,000.00   Educational Grants
 Chemistry Foundation, The
Medscape, LLC                     $250,000.00   Educational Grants
Medscape, LLC                     $250,000.00   Educational Grants
Medscape, LLC                     $100,000.00   Educational Grants
Medscape, LLC                      $75,000.00   Educational Grants
Medscape, LLC                     $740,500.00   Educational Grants
Medscape, LLC                     $471,000.00   Educational Grants
Medscape, LLC                      $37,000.00   Educational Grants
Medscape, LLC                     $155,000.00   Educational Grants
Medscape, LLC                     $150,000.00   Educational Grants
Memorial Hermann Foundation        $40,000.00   Fellowships and
                                                 Scholarships
Memphis Business Group on           $4,820.00   Corporate Sponsorship
 Health
Mercer County Joint                 $2,646.00   Patient Support
 Township Community
 Hospital dba Mercer Health
Methodist Hospital, The            $25,000.00   Corporate Sponsorship
Michael J. Fox Foundation          $32,000.00   Educational Grants
Michael J. Fox Foundation          $25,000.00   Corporate Sponsorship
Michael J. Fox Foundation          $25,000.00   Corporate Sponsorship
Michigan Council of Nurse           $1,200.00   Educational Grants
 Practitioners
Michigan Institute of               $5,000.00   Corporate Sponsorship
 Urology
Mid Atlantic Business Group         $3,000.00   Corporate Sponsorship
 Health
Mid-America Coalition on            $1,000.00   Corporate Sponsorship
 Health Care
Miles for Cystic Fibrosis           $5,000.00   Corporate Sponsorship
Mississippi Kidney                  $2,000.00   Educational Grants
 Foundation
Missouri Hepatitis C               $20,000.00   Charitable Donations
 Alliance
Missouri Hepatitis C               $10,000.00   Patient Support
 Alliance
Montana Association of              $2,000.00   Corporate Sponsorship
 Health Care Purchaser
Mount Sinai School of              $40,000.00   Fellowships and
 Medicine                                        Scholarships
Mount Sinai School of             $240,000.00   Educational Grants
 Medicine
Mount Sinai School of              $10,000.00   Charitable Donations
 Medicine
Mount Sinai School of              $20,000.00   Educational Grants
 Medicine
Mount Sinai School of               $8,000.00   Educational Grants
 Medicine
Mount Sinai School of              $10,000.00   Educational Grants
 Medicine
Movement Disorder Society,         $12,000.00   Educational Grants
 The
Movement Disorder Society,        $234,000.00   Corporate Sponsorship
 The
National Academy of                $40,000.00   Educational Grants
 Sciences
National Academy of                $10,000.00   Charitable Donations
 Sciences
National Academy of                $85,000.00   Corporate Sponsorship
 Sciences
National AIDS Treatment           $300,000.00   Charitable Donations
 Advocacy Project
National Alliance of State        $100,000.00   Charitable Donations
 and Territorial AIDS
 Directors
National Association for          $100,000.00   Educational Grants
 Continuing Education
National Association of            $11,500.00   Corporate Sponsorship
 Chain Drug Stores, Inc.
National Association of            $25,000.00   Educational Grants
 Managed Care Physicians
National Association of            $35,000.00   Educational Grants
 Managed Care Physicians
National Association of            $10,000.00   Charitable Donations
 School Nurses, Inc.
National Commission on              $5,000.00   Educational Grants
 Correctional Health Care
National Committee for             $10,000.00   Corporate Sponsorship
 Quality Assurance
National Committee for            $150,000.00   Educational Grants
 Quality Assurance
National Committee for             $10,000.00   Corporate Sponsorship
 Quality Assurance
National Committee for            $125,000.00   Corporate Sponsorship
 Quality Assurance
National Comprehensive             $10,000.00   Educational Grants
 Cancer Network
National Comprehensive            $(1,492.41)   Educational Grants
 Cancer Network
National Comprehensive             $10,000.00   Educational Grants
 Cancer Network
National Comprehensive             $25,000.00   Charitable Donations
 Cancer Network
National Comprehensive             $10,000.00   Corporate Sponsorship
 Cancer Network
National Foundation for the       $500,000.00   Corporate Sponsorship
 Centers for Disease
 Control and Prevention
National Foundation for the        $37,500.00   Corporate Sponsorship
 Centers for Disease
 Control and Prevention
National Hispanic Council          $10,000.00   Charitable Donations
 on Aging
National Jewish Health            $151,840.00   Educational Grants
National Jewish Health             $75,000.00   Educational Grants
National Kidney Foundation            $500.00   Corporate Sponsorship
 of Louisiana, Inc.
National Kidney Foundation          $3,000.00   Patient Support
 of Northeast New York
National Kidney Foundation,         $5,000.00   Corporate Sponsorship
 Inc.
National Kidney Foundation,        $20,000.00   Educational Grants
 Inc.
National Kidney Foundation,       $333,333.33   Corporate Sponsorship
 Inc.
National Medical                    $5,000.00   Corporate Sponsorship
 Association
National Multiple Sclerosis        $10,000.00   Corporate Sponsorship
 Society
National Pancreas                   $6,000.00   Corporate Sponsorship
 Foundation
National Pancreas                 $200,000.00   Educational Grants
 Foundation
National Pancreas                  $50,000.00   Charitable Donations
 Foundation
National Pancreas                  $65,000.00   Educational Grants
 Foundation
National Parkinson                 $25,000.00   Corporate Sponsorship
 Foundation, Inc.
National Parkinson                 $40,000.00   Educational Grants
 Foundation, Inc.
National Parkinson                 $25,000.00   Educational Grants
 Foundation, Inc.
National Psoriasis                $125,000.00   Corporate Sponsorship
 Foundation
National Psoriasis                 $20,000.00   Educational Grants
 Foundation
National Psoriasis                $500,000.00   Corporate Sponsorship
 Foundation
National Psoriasis                 $20,000.00   Educational Grants
 Foundation
National Psoriasis                  $2,500.00   Corporate Sponsorship
 Foundation
National Psoriasis                 $50,000.00   Patient Support
 Foundation
National Psoriasis                 $15,000.00   Corporate Sponsorship
 Foundation
National Psoriasis                  $1,000.00   Corporate Sponsorship
 Foundation
National Psoriasis                $125,000.00   Corporate Sponsorship
 Foundation
National Society for               $50,000.00   Corporate Sponsorship
 Cutaneous Medicine
National Society for              $100,000.00   Corporate Sponsorship
 Cutaneous Medicine
National Society for              $100,000.00   Corporate Sponsorship
 Cutaneous Medicine
NephCure Foundation                 $5,000.00   Patient Support
Neuro Community Foundation          $2,000.00   Educational Grants
New England Baptist                 $5,000.00   Corporate Sponsorship
 Hospital
New Jersey Association for          $2,000.00   Educational Grants
 Biomedical Research
New York Academy of                 $2,000.00   Educational Grants
 Sciences
New York Academy of                 $5,000.00   Educational Grants
 Sciences
New York Academy of                 $2,500.00   Educational Grants
 Sciences
New York Medical College,           $2,000.00   Educational Grants
 office of Continuing
 Medical Education
New York State Rheumatology        $17,500.00   Corporate Sponsorship
 Society
New York University School          $5,000.00   Educational Grants
 of Medicine
New York University School         $40,000.00   Fellowships and
 of Medicine                                     Scholarships
New York University School          $5,000.00   Educational Grants
 of Medicine
New York University School          $5,800.00   Educational Grants
 of Medicine
New York University School         $55,000.00   Educational Grants
 of Medicine
New York University School         $15,000.00   Educational Grants
 of Medicine
New York University School          $5,000.00   Educational Grants
 of Medicine
Nicole Jarvis MD Parkinsons           $500.00   Corporate Sponsorship
 Research Foundation
NL Communications, Inc.            $35,000.00   Educational Grants
NL Communications, Inc.            $25,000.00   Educational Grants
NL Communications, Inc.            $50,000.00   Educational Grants
No AIDS Task force                  $2,000.00   Educational Grants
North American Center for         $252,250.00   Educational Grants
 Continuing Medical
 Education
North American Center for          $45,000.00   Educational Grants
 Continuing Medical
 Education
North American Center for         $124,975.00   Educational Grants
 Continuing Medical
 Education
North American Center for         $318,000.00   Educational Grants
 Continuing Medical
 Education
North American Center for          $95,000.00   Educational Grants
 Continuing Medical
 Education
North American Center for         $475,000.00   Educational Grants
 Continuing Medical
 Education
North American Center for         $200,000.00   Educational Grants
 Continuing Medical
 Education
North American Center for         $250,000.00   Educational Grants
 Continuing Medical
 Education
North American Center for          $99,500.00   Educational Grants
 Continuing Medical
 Education
North American Center for         $225,000.00   Educational Grants
 Continuing Medical
 Education
North American Society for         $20,000.00   Educational Grants
 Pediatric
 Gastroenterology,
 Hepatology, and Nutrition
North Carolina Rheumatology        $20,000.00   Corporate Sponsorship
 Association
North Dakota Academy of             $1,500.00   Educational Grants
 Physician Assistants
Northeast Business Group on         $8,000.00   Corporate Sponsorship
 Health
Northwest Arthritis and           $150,000.00   Educational Grants
 Osteoporosis Institute
Northwest Kidney Centers            $2,500.00   Corporate Sponsorship
Northwest Kidney Centers            $2,500.00   Corporate Sponsorship
Northwest Urological                $5,000.00   Corporate Sponsorship
 Society
Northwestern Lake forest              $984.00   Charitable Donations
 Hospital
Northwestern University             $2,220.00   Charitable Donations
Northwestern University             $2,220.00   Charitable Donations
Northwestern University            $40,000.00   Fellowships and
                                                 Scholarships
Northwestern University             $5,000.00   Educational Grants
Northwestern University            $40,000.00   Fellowships and
                                                 Scholarships
Northwestern University            $50,000.00   Fellowships and
                                                 Scholarships
Northwestern University             $5,000.00   Educational Grants
Northwestern University             $7,500.00   Educational Grants
Ohio Association of                $10,000.00   Corporate Sponsorship
 Rheumatology
Ohio Gastroenterology               $5,000.00   Corporate Sponsorship
 Society
Oregon Health & Science               $800.00   Educational Grants
 University
Osteoarthritis Research            $10,000.00   Educational Grants
 Society International
Pacific Dermatologic               $10,000.00   Corporate Sponsorship
 Association
PACK Health, LLC                  $135,875.00   Educational Grants
Pancreas Club, The                 $10,000.00   Educational Grants
Pancreatic Cancer Action            $2,500.00   Corporate Sponsorship
 Network, Inc.
Pancreatic Cancer Action            $2,500.00   Corporate Sponsorship
 Network, Inc.
Pancreatic Cancer Action            $5,000.00   Corporate Sponsorship
 Network, Inc.
Pancreatic Cancer Action            $5,000.00   Corporate Sponsorship
 Network, Inc.
Pancreatic Cancer Action            $5,000.00   Corporate Sponsorship
 Network, Inc.
Pancreatic Cancer Action            $5,000.00   Corporate Sponsorship
 Network, Inc.
Pancreatic Cancer Action            $5,000.00   Corporate Sponsorship
 Network, Inc.
Pancreatic Cancer Action          $147,600.00   Corporate Sponsorship
 Network, Inc.
Pancreatic Cancer Action            $5,000.00   Corporate Sponsorship
 Network, Inc.
Pancreatic Cancer Action            $5,000.00   Corporate Sponsorship
 Network, Inc.
Pancreatic Cancer Action            $5,000.00   Corporate Sponsorship
 Network, Inc.
Parkinson Association of            $7,500.00   Educational Grants
 the Rockies
Parkinson Foundation of the         $5,000.00   Educational Grants
 National Capital Area
Parkinson Research                 $10,000.00   Educational Grants
 Foundation
Parkinson Research                  $5,000.00   Educational Grants
 Foundation
Parkinson Research                  $5,000.00   Educational Grants
 Foundation
Parkinson Study Group               $8,000.00   Educational Grants
Parkinson Support Group of          $2,000.00   Educational Grants
 Upstate NY dba NPF Greater
 Rochester
Parkinson's Action Network         $35,000.00   Corporate Sponsorship
 Foundation
Parkinson's Action Network         $15,000.00   Corporate Sponsorship
 Foundation
Parkinson's Action Network         $25,000.00   Corporate Sponsorship
 Foundation
Parkinson's Disease                $20,000.00   Educational Grants
 Foundation
Parkinson's Disease                $50,000.00   Educational Grants
 Foundation
Parkinsons Resources of             $5,000.00   Educational Grants
 Oregon
Parkinsons Resources of             $5,000.00   Educational Grants
 Oregon
Parkinson's Unity Walk            $150,000.00   Corporate Sponsorship
Parkinsons Voice Project            $1,000.00   Corporate Sponsorship
Partners HealthCare System         $40,000.00   Educational Grants
Partnership for a Drug Free       $100,000.00   Charitable Donations
 America
Patient Empowerment Network        $20,000.00   Educational Grants
Patient Empowerment Network        $15,000.00   Educational Grants
Pediatric IBD Foundation           $15,000.00   Corporate Sponsorship
Peer Health Communications,        $50,000.00   Educational Grants
 LLC
Pennsylvania Prostate               $5,000.00   Educational Grants
 Cancer Coalition
Pennsylvania Society of            $11,400.00   Corporate Sponsorship
 Gastroenterology
Pennsylvania State                 $75,000.00   Educational Grants
 University
Pennsylvania State                $456,750.00   Educational Grants
 University
Pennsylvania State                  $5,000.00   Educational Grants
 University
Pharmaceutical Care                $50,000.00   Corporate Sponsorship
 Management Association
Pharmaceutical Care                $75,000.00   Corporate Sponsorship
 Management Association
Pharmaceutical Research and       $200,000.00   Charitable Donations
 Manufacturers of America
 Foundation
Pharmacy Quality Alliance          $15,000.00   Educational Grants
Pharmacy Quality Alliance          $12,500.00   Educational Grants
Pharmacy Times office of           $90,000.00   Educational Grants
 Continuing Professional
 Education
Pharmacy Times office of           $25,000.00   Educational Grants
 Continuing Professional
 Education
Physicians Education               $45,000.00   Educational Grants
 Resource
Pittsburgh Magazine                 $3,500.00   Corporate Sponsorship
Postgraduate Institute for        $245,035.00   Educational Grants
 Medicine
Potomac Center for Medical          $(550.00)   Educational Grants
 Education
President and Fellows of           $25,000.00   Corporate Sponsorship
 Harvard College
Prevent Cancer Foundation          $10,000.00   Corporate Sponsorship
Primary Care Network, Inc.        $142,375.00   Educational Grants
Prime Education, Inc.             $100,110.00   Educational Grants
Prime Education, Inc.             $148,780.00   Educational Grants
Prime Education, Inc.             $482,600.00   Educational Grants
Prime Education, Inc.             $138,850.00   Educational Grants
Prime Education, Inc.               $(769.00)   Educational Grants
Prime Education, Inc.             $315,393.00   Educational Grants
Prime Oncology, Inc.               $10,000.00   Educational Grants
Prime Oncology, Inc.               $35,000.00   Educational Grants
Prime Oncology, Inc.               $30,000.00   Educational Grants
Pri-Med Institute, LLC             $77,500.00   Educational Grants
Princeton University,              $50,000.00   Fellowships and
 Trustees                                        Scholarships
Project Inform, Inc.               $75,000.00   Educational Grants
Project Inform, Inc.               $75,000.00   Charitable Donations
Projects In Knowledge, Inc.       $125,000.00   Educational Grants
Projects In Knowledge, Inc.       $150,000.00   Educational Grants
Prostate Cancer Foundation          $5,000.00   Corporate Sponsorship
 Rodin Group
Prostate Cancer Research           $25,000.00   Educational Grants
 Institute
Prostate Cancer Research           $10,000.00   Corporate Sponsorship
 Institute
Prostate Conditions                 $2,500.00   Corporate Sponsorship
 Education Council
Prostate Health Education          $15,000.00   Patient Support
 Network
Prostate Health Education          $15,000.00   Educational Grants
 Network
Prostate Health                     $5,000.00   Corporate Sponsorship
 International
Puerto Rico Association of         $10,000.00   Educational Grants
 Gastroenterology
Puerto Rico Association of         $10,000.00   Educational Grants
 Gastroenterology
Purdue University                  $83,890.00   Educational Grants
Purdue University                 $400,000.00   Educational Grants
Purdue University                 $450,000.00   Educational Grants
Rector & Visitors of the           $25,000.00   Educational Grants
 University of Virginia
Regents of the University          $40,000.00   Fellowships and
 of California, The                              Scholarships
Regents of the University           $5,000.00   Educational Grants
 of California, The
Regents of the University          $12,000.00   Corporate Sponsorship
 of California, The
Regents of the University           $5,000.00   Educational Grants
 of California, The
Regents of the University           $8,000.00   Educational Grants
 of California, The
Regents of the University          $10,000.00   Educational Grants
 of California, The
Regents of the University          $10,000.00   Corporate Sponsorship
 of Michigan
Research America                   $25,000.00   Corporate Sponsorship
Rheumatology Alliance of           $25,000.00   Corporate Sponsorship
 Louisiana
Rheumatology Nurses Society        $50,000.00   Educational Grants
Rheumatology Nurses Society        $74,225.00   Educational Grants
Rheumatology Nurses Society        $50,000.00   Educational Grants
Rheumatology Nurses Society         $7,500.00   Corporate Sponsorship
Richmond University Medical         $1,100.00   Educational Grants
 Center
Robert Michael Educational         $70,000.00   Educational Grants
 Institute, LLC
Robert Michael Educational        $150,000.00   Educational Grants
 Institute, LLC
Rush University Medical            $40,000.00   Educational Grants
 Center
Rush University Medical             $5,000.00   Patient Support
 Center
Rush University Medical            $10,000.00   Educational Grants
 Center
Rutgers, The State                $125,000.00   Educational Grants
 University of New Jersey
Rutgers, The State                 $60,000.00   Educational Grants
 University of New Jersey
Rutgers, The State                 $75,000.00   Educational Grants
 University of New Jersey
Rutgers, The State                 $25,000.00   Educational Grants
 University of New Jersey
Sacramento Valley Society             $500.00   Corporate Sponsorship
 of Health System
 Pharmacists
Safety Pharmacology Society         $2,500.00   Educational Grants
Saint Anthony Hospital              $3,410.00   Patient Support
 Foundation
Saint Louis University              $5,000.00   Educational Grants
San Francisco AIDS                 $25,000.00   Corporate Sponsorship
 Foundation
San Juan Bautista Medical          $40,000.00   Fellowships and
                                                 Scholarships
Schneps Publications Inc.             $695.00   Corporate Sponsorship
 DBA Queens Courier
Scripps Health                    $150,000.00   Educational Grants
Sexual Medicine Society of         $55,000.00   Corporate Sponsorship
 North America, Inc.
Sexual Medicine Society of        $225,000.00   Corporate Sponsorship
 North America, Inc.
Shanti Project, Inc.               $20,000.00   Educational Grants
Skin Disease Education             $30,000.00   Corporate Sponsorship
 Foundation
Skin Disease Education             $80,000.00   Corporate Sponsorship
 Foundation
Skin Disease Education             $42,750.00   Corporate Sponsorship
 Foundation
Skin Disease Education             $46,250.00   Corporate Sponsorship
 Foundation
Smart Ride, The                    $20,000.00   Corporate Sponsorship
Smith Wholesale Drug                $9,000.00   Corporate Sponsorship
 Company
Sociedad Pr Endocrinologia        $(7,500.00)   Educational Grants
 Y Diabetologia
Sociedad Puertorriquena             $1,000.00   Educational Grants
 Pediatria
Society for Neuroscience            $2,500.00   Educational Grants
Society for Neuroscience,           $1,000.00   Educational Grants
 Chicago Chapter
Society for Surgery of The          $7,000.00   Corporate Sponsorship
 Alimentary Tract
Society of Dermatology             $20,000.00   Corporate Sponsorship
 Physician Assistants
Society of Toxicologic             $15,000.00   Corporate Sponsorship
 Pathology
Society of Toxicology               $5,000.00   Corporate Sponsorship
South Carolina Alliance of          $5,000.00   Corporate Sponsorship
 Health Plans
Southern California Society         $5,500.00   Corporate Sponsorship
 of Gastroenterologists
Southern California Society        $10,000.00   Educational Grants
 of Gastroenterology
Southern Illinois                   $3,000.00   Fellowships and
 University School of                            Scholarships
 Medicine
Spondylitis Association of         $40,000.00   Patient Support
 America
Spondylitis Association of         $19,084.50   Educational Grants
 America
St. Francis Hospital and           $20,000.00   Educational Grants
 Medical Center
State of Maryland                 $(1,308.80)   Educational Grants
State of Maryland                  $45,000.00   Fellowships and
                                                 Scholarships
State University of Iowa            $1,500.00   Educational Grants
States United for                   $5,000.00   Charitable Donations
 Biomedical Research
Super Jake Foundation, The         $25,000.00   Corporate Sponsorship
Teratology Society                  $1,500.00   Educational Grants
Test positive Aware Network         $2,500.00   Patient Support
Test positive Aware Network        $30,000.00   Corporate Sponsorship
Texas Association of Health         $1,500.00   Corporate Sponsorship
 Plans
Texas Urological Society            $6,000.00   Corporate Sponsorship
The Endocrine Society              $25,000.00   Educational Grants
The Hitchcock Foundation           $25,000.00   Educational Grants
The Reginald and Dionne             $5,000.00   Patient Support
 Smith Foundation, Inc.
The Reginald and Dionne             $5,000.00   Patient Support
 Smith Foundation, Inc.
Tides Center                       $10,000.00   Educational Grants
Tides Center                       $50,000.00   Educational Grants
Tides Center                       $50,000.00   Educational Grants
Trinitas Regional Medical           $1,800.00   Educational Grants
 Center
Triple Step Toward the Cure         $5,000.00   Corporate Sponsorship
Trustees of the University         $69,742.00   Educational Grants
 of Pennsylvania
Trustees of the University         $50,000.00   Educational Grants
 of Pennsylvania
Tufts Medical Center              $(3,825.00)   Educational Grants
Tufts Medical Center                $4,000.00   Fellowships and
                                                 Scholarships
Tufts University                    $8,000.00   Educational Grants
Twine Clinical Consulting         $158,000.00   Educational Grants
 LLC
UC Regents Maxillofacial           $20,000.00   Educational Grants
 Prosthetics Clinic
UC Regents Maxillofacial           $50,000.00   Fellowships and
 Prosthetics Clinic                              Scholarships
UC Regents Maxillofacial           $50,000.00   Fellowships and
 Prosthetics Clinic                              Scholarships
UC Regents Maxillofacial            $5,000.00   Educational Grants
 Prosthetics Clinic
UC Regents Maxillofacial           $20,000.00   Educational Grants
 Prosthetics Clinic
Ultimate Medical Academy           $90,000.00   Educational Grants
 Med Learning Group, LLC
Ultimate Medical Academy        $(125,000.00)   Educational Grants
 Med Learning Group, LLC
United States Adult Cystic          $6,000.00   Educational Grants
 Fibrosis Association, Inc.
United Way of Central               $5,000.00   Corporate Sponsorship
 Massachusetts
Universidad De Puerto Rico         $40,000.00   Fellowships and
                                                 Scholarships
Universidad De Puerto Rico          $6,325.00   Educational Grants
University Health Services         $25,000.00   Educational Grants
 at Stony Point, Inc.
University Health Services        $150,111.40   Educational Grants
 at Stony Point, Inc.
University Hospital of             $10,000.00   Educational Grants
 Brooklyn
University of Alabama at           $40,000.00   Fellowships and
 Birmingham                                      Scholarships
University of California            $5,000.00   Educational Grants
University of California--         $15,000.00   Corporate Sponsorship
 San Francisco
University of California--         $10,000.00   Educational Grants
 San Francisco
University of California--         $10,000.00   Educational Grants
 San Francisco
University of California           $30,000.00   Charitable Donations
 Berkeley
University of California           $40,000.00   Fellowships and
 Irvine                                          Scholarships
University of Chicago              $60,000.00   Educational Grants
University of Chicago              $28,961.64   Fellowships and
                                                 Scholarships
University of Chicago               $5,000.00   Educational Grants
University of Chicago             $204,525.00   Educational Grants
University of Chicago               $5,000.00   Educational Grants
University of Chicago             $150,000.00   Educational Grants
University of Chicago              $75,000.00   Educational Grants
University of Chicago             $100,000.00   Educational Grants
University of Chicago              $25,000.00   Charitable Donations
 Cancer Research Foundation
University of Cincinnati          $100,000.00   Corporate Sponsorship
University of Cincinnati           $75,000.00   Educational Grants
University of Cincinnati          $100,000.00   Educational Grants
University of Cincinnati           $75,000.00   Educational Grants
University of Cincinnati          $100,000.00   Educational Grants
University of Cincinnati           $50,000.00   Educational Grants
University of Cincinnati        $2,542,080.00   Educational Grants
University of Cincinnati           $50,000.00   Corporate Sponsorship
University of Cincinnati            $8,000.00   Educational Grants
University of Cincinnati           $10,000.00   Educational Grants
University of Connecticut          $12,000.00   Fellowships and
                                                 Scholarships
University of Florida             $142,709.00   Educational Grants
University of Florida              $65,000.00   Educational Grants
University of Florida              $50,000.00   Fellowships and
 Foundation                                      Scholarships
University of Illinois              $2,220.00   Charitable Donations
 Foundation
University of Illinois              $2,220.00   Charitable Donations
 Foundation
University of Louisville            $2,220.00   Charitable Donations
 Foundation
University of Louisville          $150,000.00   Educational Grants
 Research Foundation
University of Louisville           $35,000.00   Educational Grants
 Research Foundation
University of Louisville           $25,000.00   Educational Grants
 Research Foundation
University of Maryland             $10,000.00   Educational Grants
 Baltimore Foundation
University of Massachusetts        $10,000.00   Charitable Donations
 Medical School
University of Miami               $112,000.00   Educational Grants
University of Michigan              $(254.37)   Educational Grants
University of Minnesota             $2,220.00   Charitable Donations
University of Minnesota,            $5,000.00   Educational Grants
 Regents
University of Minnesota,            $(160.43)   Corporate Sponsorship
 Regents
University of Mississippi          $10,000.00   Charitable Donations
 Foundation
University of Nebraska              $5,000.00   Educational Grants
 Medical Center
University of Nebraska              $2,500.00   Educational Grants
 Medical Center
University of Nebraska             $15,000.00   Educational Grants
 Medical Center
University of New Mexico          $142,150.00   Educational Grants
 Health Sciences Center,
 Department of Pediatrics
 Neonatology Division
University of North                $50,000.00   Fellowships and
 Carolina at Chapel Hill                         Scholarships
University of North                 $5,000.00   Educational Grants
 Carolina at Chapel Hill
University of Notre Dame            $1,000.00   Educational Grants
University of Pittsburgh            $1,500.00   Fellowships and
                                                 Scholarships
University of Pittsburgh           $10,000.00   Educational Grants
University of Pittsburgh           $20,000.00   Educational Grants
University of Rochester            $40,000.00   Fellowships and
                                                 Scholarships
University of Rochester             $4,225.00   Educational Grants
University of Rochester           $(1,207.00)   Educational Grants
University of South Florida       $150,000.00   Educational Grants
 Health Professions
 Conferencing Corporation
University of Southern            $180,000.00   Educational Grants
 California
University of Southern              $1,500.00   Educational Grants
 California
University of Southern             $30,000.00   Educational Grants
 California
University of Texas Health         $25,000.00   Educational Grants
 Science Center at San
 Antonio
University of Texas Health         $10,000.00   Educational Grants
 Science Center at San
 Antonio
University of Texas Health         $10,000.00   Educational Grants
 Science Center at San
 Antonio
University of Texas M.D.           $20,000.00   Educational Grants
 Anderson Cancer Center
University of Texas M.D.           $10,000.00   Educational Grants
 Anderson Cancer Center
University of Utah                 $40,000.00   Fellowships and
                                                 Scholarships
University of Utah                  $2,200.00   Educational Grants
University of Washington           $50,000.00   Fellowships and
                                                 Scholarships
University of Washington           $40,000.00   Fellowships and
                                                 Scholarships
University of Wisconsin             $2,220.00   Charitable Donations
 Medical Foundation
University of Wisconsin             $2,000.00   Educational Grants
 Systems
University of Wisconsin             $(500.00)   Corporate Sponsorship
 Systems
University of Wisconsin-          $(1,857.88)   Educational Grants
 Madison
University of Wisconsin-            $2,000.00   Educational Grants
 Madison
Urological Association of           $2,500.00   Educational Grants
 Pennsylvania
Urology Center of Colorado          $7,500.00   Corporate Sponsorship
 Foundation
Us Too International               $15,000.00   Educational Grants
Us Too International                $5,000.00   Educational Grants
Us Too International               $25,000.00   Corporate Sponsorship
Us Too International                $5,000.00   Corporate Sponsorship
Us Too International                $1,000.00   Corporate Sponsorship
Valley Children's Hospital          $2,500.00   Patient Support
 Foundation
Venice Family Clinic               $10,000.00   Charitable Donations
Veritas Institute for            $(50,000.00)   Educational Grants
 Medical Education, Inc.
Vindico Medical Education         $337,509.00   Educational Grants
Virginia Commonwealth               $2,100.00   Patient Support
 University, School of
 Medicine
Wake forest University             $40,000.00   Fellowships and
                                                 Scholarships
Washington Hospital Center         $10,000.00   Educational Grants
 Corporation
Washington Rheumatology            $30,000.00   Corporate Sponsorship
 Alliance
Washington State Urology            $5,000.00   Corporate Sponsorship
 Society
Washington University in            $2,220.00   Charitable Donations
 St. Louis
Wayne State University              $2,220.00   Charitable Donations
We Care in Inflammatory            $50,000.00   Charitable Donations
 Bowel Disease
West Penn Allegheny Health          $6,000.00   Educational Grants
 System, Inc.
West Penn Allegheny Health        $(5,905.00)   Fellowships and
 System, Inc.                                    Scholarships
West Virginia University            $2,220.00   Charitable Donations
Western States Pharmacy             $7,500.00   Corporate Sponsorship
 Conference for Pharmacy
 Residents Fellowships and
 Preceptors
Why Me, Inc.                        $2,500.00   Charitable Donations
WINGS Program Inc.                 $25,000.00   Charitable Donations
Wisconsin Dairyland Chapter         $2,000.00   Corporate Sponsorship
 of Healthcare Information
 and Management Systems
 Society
Wisconsin Rheumatology             $10,000.00   Corporate Sponsorship
 Association
Wishes And Dreams for               $1,000.00   Corporate Sponsorship
 Cystic Fibrosis
Worcester Regional Research         $2,500.00   Corporate Sponsorship
 Bureau, Inc.
World Endometriosis                $18,000.00   Corporate Sponsorship
 Research Foundation
World Endometriosis Society       $150,000.00   Corporate Sponsorship
World Endometriosis Society       $150,000.00   Corporate Sponsorship
World Health                       $50,000.00   Educational Grants
 Communications, Ltd.
World Parkinson Coalition          $15,000.00   Educational Grants
 Inc.
World Senior Games                  $5,250.00   Corporate Sponsorship
Yale University School of           $5,000.00   Educational Grants
 Medicine
Yale University School of        $(10,000.00)   Educational Grants
 Medicine
Yale University School of          $10,000.00   Educational Grants
 Medicine
Young Survival Coalition            $5,000.00   Corporate Sponsorship
Zero, The Project to End            $7,500.00   Corporate Sponsorship
 Prostate Cancer
Zero, The Project to End          $210,800.00   Corporate Sponsorship
 Prostate Cancer
Zero, The Project to End           $15,000.00   Corporate Sponsorship
 Prostate Cancer
Zero, The Project to End            $2,500.00   Corporate Sponsorship
 Prostate Cancer
------------------------------------------------------------------------


                      Grants Donations Report--2015
    (Parentheses represent refunds of previously disclosed payments)
                         Updated as of 4/30/2018
------------------------------------------------------------------------
         Recipient             Payment Amount           Purpose
------------------------------------------------------------------------
A Runner's Love                     $5,000.00   Corporate Sponsorship
Academia Medica Del Sur            $12,000.00   Educational Grants
Academia Medica Del Sur             $8,000.00   Educational Grants
Academia Medica Del Sur            $15,000.00   Educational Grants
Academia Medica Del Sur            $15,000.00   Educational Grants
Academia Medica Del Sur            $10,000.00   Educational Grants
Academia Medica Del Sur            $10,000.00   Educational Grants
Academia Medica Del Sur             $9,000.00   Educational Grants
Academia Medica Del Sur            $12,000.00   Educational Grants
Academia Medica Del Sur            $14,000.00   Educational Grants
Academia Medica Del Sur            $10,000.00   Educational Grants
Academia Medica Del Sur            $10,000.00   Educational Grants
Academia Medica Del Sur            $15,000.00   Educational Grants
Academia Medica Del Sur             $5,000.00   Educational Grants
Academia Medica Del Sur            $15,000.00   Educational Grants
Academia Medica Del Sur            $10,000.00   Educational Grants
Academia Medica Del Sur             $5,000.00   Educational Grants
Academia Medica Del Sur             $7,500.00   Educational Grants
Academia Medica Del Sur            $12,000.00   Educational Grants
Academia Medica Del Sur            $10,000.00   Educational Grants
Academia Medica Del Sur             $7,500.00   Educational Grants
Academia Medica Del Sur            $10,000.00   Educational Grants
Academia Medica Del Sur            $10,000.00   Educational Grants
Academia Medica Del Sur            $15,000.00   Educational Grants
Academia Medica Del Sur            $10,000.00   Educational Grants
Academia Medica Del Sur            $12,000.00   Educational Grants
Academia Medica Del Sur            $15,000.00   Educational Grants
Academia Medica Del Sur            $15,000.00   Educational Grants
Academia Medica Del Sur            $10,000.00   Educational Grants
Academia Medica Del Sur            $10,000.00   Educational Grants
Academia Medica Del Sur            $15,000.00   Educational Grants
Academia Medica Del Sur            $10,000.00   Educational Grants
Academia Medica Del Sur            $15,000.00   Educational Grants
Academia Medica Del Sur            $10,000.00   Educational Grants
Academia Medica Del Sur            $10,000.00   Educational Grants
Academia Medica Del Sur             $9,000.00   Educational Grants
Academia Medica Del Sur            $10,000.00   Educational Grants
Academia Medica Del Sur            $15,000.00   Educational Grants
Academia Puertorriquena De          $8,500.00   Corporate Sponsorship
 Neurologia
Academy of Managed Care            $25,000.00   Corporate Sponsorship
 Pharmacy
Academy of Managed Care            $75,000.00   Corporate Sponsorship
 Pharmacy
Academy of Managed Care            $30,000.00   Corporate Sponsorship
 Pharmacy
Academy of Managed Care            $25,000.00   Corporate Sponsorship
 Pharmacy
Academy of Managed Care            $40,000.00   Corporate Sponsorship
 Pharmacy
Advances in Cosmetic and           $50,000.00   Corporate Sponsorship
 Medical Dermatology Inc.
Advances in Cosmetic and           $50,000.00   Corporate Sponsorship
 Medical Dermatology Inc.
Advances in Cosmetic and          $100,000.00   Corporate Sponsorship
 Medical Dermatology Inc.
Adventist Hlth System--            $15,000.00   Corporate Sponsorship
 Sunbelt Inc.
Advocate Health & Hospitals         $2,500.00   Educational Grants
 Corporation
Aids Drug Assistance                $5,000.00   Educational Grants
 Programs Advocacy Asoc
AIDS Action Committee               $5,000.00   Corporate Sponsorship
AIDS Foundation of Chicago        $125,000.00   Charitable Donation
AIDS Foundation of Chicago         $25,000.00   Corporate Sponsorship
AIDS Foundation of Chicago         $10,000.00   Corporate Sponsorship
Alabama Dermatology Society        $35,000.00   Corporate Sponsorship
Albany Medical Center              $10,000.00   Corporate Sponsorship
Albany Medical Center               $5,000.00   Educational Grants
Albert Einstein Colg of            $10,000.00   Educational Grants
 Medicine Div of
 Dermatology Attending Asoc
Albert Einstein Colg of            $85,000.00   Educational Grants
 Medicine of Yeshiva Univ
Albert Einstein Med Ctr.            $2,500.00   Educational Grants
Alliance for Clinical              $25,000.00   Educational Grants
 Trials in Oncology
 Foundation
Alliance for Safe Biologic        $100,000.00   Corporate Sponsorship
 Medicines
Alliance Foundation for            $50,000.00   Educational Grants
 Continuing Education In
 The Health Professions
American Academy of                $75,000.00   Educational Grants
 Continuing Medical
 Education
American Academy of              ($37,982.00)   Educational Grants
 Dermatology
American Academy of                $75,000.00   Educational Grants
 Dermatology
American Academy of                $40,000.00   Charitable Donation
 Dermatology
American Academy of                $35,000.00   Corporate Sponsorship
 Dermatology
American Academy of                $40,000.00   Educational Grants
 Dermatology
American Academy of                $20,000.00   Corporate Sponsorship
 Dermatology
American Academy of                $10,000.00   Corporate Sponsorship
 Dermatology
American Academy of                $35,000.00   Corporate Sponsorship
 Dermatology
American Academy of               $200,000.00   Corporate Sponsorship
 Dermatology
American Academy of Family         $38,000.00   Corporate Sponsorship
 Phys
American Academy of Family         $38,000.00   Corporate Sponsorship
 Phys
American Academy of                $38,500.00   Educational Grants
 Neurology Institute
American Academy of                $10,000.00   Educational Grants
 Neurology Institute
American Assoc for Lab             $20,000.00   Charitable Donation
 Animal Scnc Foundation
American Assoc for The             $50,000.00   Charitable Donation
 Study of Liver Diseases
American Assoc for The            $500,000.00   Charitable Donation
 Study of Liver Diseases
American Assoc for The            $130,000.00   Corporate Sponsorship
 Study of Liver Diseases
American Assoc of Phys of          $15,000.00   Corporate Sponsorship
 Indian Origin Arkansas
American Assoc of Phys of          $10,000.00   Corporate Sponsorship
 Indian Origin Arkansas
American Assoc of Phys of           $5,000.00   Corporate Sponsorship
 Indian Origin Arkansas
American Association for           $10,000.00   Educational Grants
 Cancer Research
American Association for           $35,000.00   Educational Grants
 Cancer Research
American Association for           $10,000.00   Educational Grants
 Cancer Research
American Association for            $5,000.00   Educational Grants
 Cancer Research
American Association for           $25,000.00   Educational Grants
 Cancer Research
American Association for           $10,000.00   Educational Grants
 Cancer Research
American Association for           $25,000.00   Educational Grants
 Cancer Research
American Association for           $10,000.00   Educational Grants
 Cancer Research
American Association for            $5,000.00   Educational Grants
 Laboratory Animal Science
 New England Branch
American Association of            $18,940.00   Educational Grants
 Clinical Endocrinologists
American Association of            $20,000.00   Educational Grants
 Clinical Endocrinologists
American Association of             $7,500.00   Educational Grants
 Clinical Endocrinologists
American Association of             $5,000.00   Educational Grants
 Clinical Endocrinologists
American Association of            $50,000.00   Corporate Sponsorship
 Pharmaceutical Scientists
American Association of             $3,150.00   Charitable Donation
 Pharmaceutical Scientists
American Autoimmune Related        $46,000.00   Corporate Sponsorship
American Autoimmune Related        $10,000.00   Corporate Sponsorship
American Autoimmune Related         $2,500.00   Corporate Sponsorship
American Autoimmune Related         $5,000.00   Corporate Sponsorship
American Autoimmune Related        $30,000.00   Corporate Sponsorship
American Brain Tumor               $10,000.00   Corporate Sponsorship
 Association
American Cancer Society            $10,000.00   Corporate Sponsorship
American Cancer Society             $2,000.00   Corporate Sponsorship
 Cancer Action Network
American Cancer Society             $7,000.00   Corporate Sponsorship
 Cancer Action Network
American Cancer Society             $5,000.00   Corporate Sponsorship
 Cancer Action Network
American Cancer Society             $2,500.00   Corporate Sponsorship
 Cancer Action Network
American Cancer Society             $1,000.00   Corporate Sponsorship
 Cancer Action Network
American Cancer Society            $10,000.00   Corporate Sponsorship
 Cancer Action Network
American Cancer Society             $2,500.00   Corporate Sponsorship
 Cancer Action Network
American Cancer Society             $1,000.00   Corporate Sponsorship
 Cancer Action Network
American Chem Socty                 $2,500.00   Educational Grants
American Chem Socty                 $1,000.00   Educational Grants
American Chem Socty                 $2,500.00   Educational Grants
American Chem Socty                 $2,500.00   Educational Grants
American Colg of                  $355,000.00   Corporate Sponsorship
 Endocrinology
American Colg of Lab Animal        $50,000.00   Charitable Donation
 Medicine
American Colg of                    $1,000.00   Corporate Sponsorship
 Obstetricians And
 Gynecologists District 1
American College of                 $1,000.00   Educational Grants
 Clinical Pharmacology
American College of                $90,000.00   Corporate Sponsorship
 Gastroenterology
American College of                $20,000.00   Corporate Sponsorship
 Gastroenterology
American College of                $25,000.00   Charitable Donation
 Gastroenterology
American College of               $100,000.00   Corporate Sponsorship
 Gastroenterology
American College of                $45,000.00   Corporate Sponsorship
 Gastroenterology
American College of                $90,000.00   Corporate Sponsorship
 Gastroenterology
American College of                $20,000.00   Corporate Sponsorship
 Gastroenterology
American College of                 $3,000.00   Corporate Sponsorship
 Healthcare Executives
 Wisconsin Chapter
American College of             $2,000,000.00   Corporate Sponsorship
 Rheumatology
American College of                 $5,000.00   Corporate Sponsorship
 Veterinary Pathologists
American Drug Utilization          $20,000.00   Corporate Sponsorship
 Review Society Adurs
American Enterprise                $10,000.00   Corporate Sponsorship
 Institute
American                          $153,517.00   Educational Grants
 Gastroenterological
 Association Institute
American                          $427,536.66   Educational Grants
 Gastroenterological
 Association Institute
American                           $25,000.00   Corporate Sponsorship
 Gastroenterological
 Association Institute
American                           $25,000.00   Corporate Sponsorship
 Gastroenterological
 Association Institute
American                          $133,200.00   Corporate Sponsorship
 Gastroenterological
 Association Institute
American                           $43,000.00   Corporate Sponsorship
 Gastroenterological
 Association Institute
American                           $25,000.00   Corporate Sponsorship
 Gastroenterological
 Association Institute
American Kidney Fund                $5,000.00   Corporate Sponsorship
American Legion                    $10,000.00   Corporate Sponsorship
American Legion National           $20,000.00   Corporate Sponsorship
 Headquarters
American Liver Foundation          $10,000.00   Corporate Sponsorship
American Liver Foundation           $4,500.00   Corporate Sponsorship
American Liver Foundation         $400,000.00   Corporate Sponsorship
American Liver Foundation        ($10,000.00)   Corporate Sponsorship
American Liver Foundation          $25,000.00   Corporate Sponsorship
American Liver Foundation           $5,000.00   Corporate Sponsorship
American Liver Foundation          $25,000.00   Corporate Sponsorship
American Liver Foundation           $5,000.00   Corporate Sponsorship
American Liver Foundation          $35,000.00   Corporate Sponsorship
American Medical Group             $24,700.00   Corporate Sponsorship
 Association
American Neurological              $25,000.00   Educational Grants
 Association
American Pancreatic                $75,000.00   Educational Grants
 Association, Inc.
American Pancreatic                $25,000.00   Corporate Sponsorship
 Association, Inc.
American Pancreatic                $15,000.00   Charitable Donation
 Association, Inc.
American Parkinson Disease          $5,350.00   Corporate Sponsorship
 Association, Inc.
American Parkinson Disease          $2,000.00   Corporate Sponsorship
 Association, Inc.
American Parkinson Disease         $15,000.00   Educational Grants
 Association, Inc.
American Parkinson Disease          $2,500.00   Corporate Sponsorship
 Association, Inc.
American Parkinson Disease         $40,000.00   Educational Grants
 Association, Inc.
American Parkinson Disease          $3,000.00   Corporate Sponsorship
 Association, Inc.
American Parkinson Disease            $500.00   Corporate Sponsorship
 Association, Inc.
American Parkinson Disease            $500.00   Corporate Sponsorship
 Association, Inc.
American Parkinson Disease          $1,000.00   Corporate Sponsorship
 Association, Inc.
American Parkinson Disease          $5,000.00   Corporate Sponsorship
 Association, Inc.
American Parkinson Disease          $1,000.00   Corporate Sponsorship
 Association, Inc.
American Parkinson Disease            $500.00   Corporate Sponsorship
 Association, Inc.
American Parkinson Disease          $1,000.00   Corporate Sponsorship
 Association, Inc.
American Parkinson Disease            $500.00   Corporate Sponsorship
 Association, Inc.
American Parkinson Disease          $1,000.00   Corporate Sponsorship
 Association, Inc.
American Peptide Society            $1,000.00   Educational Grants
American Pharmacists               $10,000.00   Corporate Sponsorship
 Association
American Society for Mens          $10,000.00   Corporate Sponsorship
 Health
American Society of                $15,000.00   Corporate Sponsorship
 Andrology
American Society of                $15,000.00   Educational Grants
 Clinical Oncology
American Society of                $25,000.00   Educational Grants
 Clinical Oncology
American Society of                $15,000.00   Educational Grants
 Clinical Oncology
American Society of                 $9,500.00   Corporate Sponsorship
 Clinical Rheumatologists
American Society of Health         $23,400.00   Corporate Sponsorship
 System Pharmacists
American Socty of                  $95,000.00   Corporate Sponsorship
 Hematology
American Socty of                   $2,550.00   Corporate Sponsorship
 Hematology
American Socty of                  $25,000.00   Corporate Sponsorship
 Hematology
American Socty of                  $60,000.00   Corporate Sponsorship
 Hematology
American Statistical                $2,500.00   Educational Grants
 Association
American Thyroid                   $45,000.00   Educational Grants
 Association, Inc.
American Uroligical Asoc           $11,500.00   Corporate Sponsorship
 Northeastern Section
American Urological Asoc           $10,000.00   Corporate Sponsorship
 Foundation
American Urological Asoc            $6,000.00   Corporate Sponsorship
 Inc. North Ctrl Section
American Urological Asoc           $10,000.00   Corporate Sponsorship
 Inc. Western Section
American Urological Asoc            $1,000.00   Corporate Sponsorship
 New York Section
American Urological Asoc            $6,000.00   Corporate Sponsorship
 South Ctrl Section
American Urological               $100,000.00   Corporate Sponsorship
 Association
American Urological                $25,000.00   Corporate Sponsorship
 Association
American Urological                $37,500.00   Corporate Sponsorship
 Association
American Urological                $41,000.00   Corporate Sponsorship
 Association
American Urological                $75,000.00   Educational Grants
 Association Education And
 Research, Inc.
American Urological                $50,000.00   Educational Grants
 Association Education And
 Research, Inc.
American Urological                $30,000.00   Educational Grants
 Association Education And
 Research, Inc.
American Urological                $10,000.00   Educational Grants
 Association Education And
 Research, Inc.
American Urological                $10,000.00   Educational Grants
 Association Education And
 Research, Inc.
American Urological                $10,000.00   Educational Grants
 Association Education And
 Research, Inc.
American Urological                $25,000.00   Educational Grants
 Association Education And
 Research, Inc.
American Urological                $10,000.00   Educational Grants
 Association Education And
 Research, Inc.
American Urological                 $8,000.00   Educational Grants
 Association Education And
 Research, Inc.
Americans for Medical             $110,000.00   Charitable Donation
 Progress Educational Found
Americares Foundation, Inc.        $10,000.00   Corporate Sponsorship
Anesthesia Patient Safety          $15,000.00   Charitable Donation
 Foundation
Annenberg Center for Health        $50,000.00   Educational Grants
 Science
Annenberg Center for Health       $140,000.00   Educational Grants
 Science
Annenberg Center for Health        $90,000.00   Educational Grants
 Science
Annenberg Center for Health       $641,628.00   Educational Grants
 Science
Annenberg Center for Health        $85,000.00   Educational Grants
 Science
Annenberg Center for Health        $75,000.00   Educational Grants
 Science
Annenberg Center for Health       ($5,000.00)   Educational Grants
 Science
Arizona United Rheum                $5,000.00   Corporate Sponsorship
 Alliance Aura
Arthritis Foundation, Inc.          $5,000.00   Corporate Sponsorship
Arthritis Foundation, Inc.          $5,000.00   Corporate Sponsorship
Arthritis Foundation, Inc.         $50,000.00   Educational Grants
Arthritis Foundation, Inc.         $30,000.00   Corporate Sponsorship
Arthritis Foundation, Inc.         $10,000.00   Educational Grants
Arthritis Foundation, Inc.          $2,500.00   Patient Support
Arthritis Foundation, Inc.         $30,000.00   Corporate Sponsorship
Arthritis Foundation, Inc.         $40,000.00   Patient Support
Arthritis Foundation, Inc.         $20,000.00   Corporate Sponsorship
Arthritis Foundation, Inc.         $12,500.00   Patient Support
Arthritis Foundation, Inc.         $25,000.00   Corporate Sponsorship
Arthritis Foundation, Inc.         $25,000.00   Corporate Sponsorship
Arthritis Foundation, Inc.          $1,500.00   Corporate Sponsorship
Arthritis Foundation, Inc.          $5,000.00   Corporate Sponsorship
Arthritis Foundation, Inc.          $5,000.00   Corporate Sponsorship
Arthritis Foundation, Inc.          $5,000.00   Corporate Sponsorship
Arthritis Foundation, Inc.          $2,000.00   Corporate Sponsorship
Arthritis Foundation, Inc.          $3,000.00   Corporate Sponsorship
Arthritis Foundation, Inc.          $1,000.00   Corporate Sponsorship
Arthritis Foundation, Inc.          $5,000.00   Corporate Sponsorship
Arthritis Foundation, Inc.          $2,000.00   Corporate Sponsorship
Arthritis Foundation, Inc.          $1,000.00   Corporate Sponsorship
Arthritis Foundation, Inc.          $2,500.00   Patient Support
Arthritis Foundation, Inc.          $5,000.00   Corporate Sponsorship
Arthritis Foundation, Inc.         $30,000.00   Corporate Sponsorship
Arthritis Foundation, Inc.        $250,000.00   Corporate Sponsorship
Arthritis Foundation, Inc.        $175,000.00   Corporate Sponsorship
Arthritis Foundation, Inc.        $300,000.00   Corporate Sponsorship
Arthritis Foundation, Inc.        $300,000.00   Corporate Sponsorship
Arthritis Foundation, Inc.        $259,000.00   Corporate Sponsorship
Arthritis Patient Services         $10,000.00   Educational Grants
Arthritis Patient Services         $25,000.00   Educational Grants
Asco Cancer Foundation             $50,000.00   Charitable Donation
Asco Cancer Foundation             $40,000.00   Fellowships or
                                                 Scholarships
Asco Cancer Foundation              ($689.37)   Fellowships or
                                                 Scholarships
Asociacion De Hematologia Y         $5,000.00   Corporate Sponsorship
 Oncologia Medica De Puerto
 Rico
Asociacion De Reumatologos         $22,500.00   Corporate Sponsorship
 De Puerto Rico
Asociacion De Salud                 $2,000.00   Corporate Sponsorship
 Primaria De Puerto Rico,
 Inc.
Asociacion Pr De                   $10,000.00   Corporate Sponsorship
 Gastroenterologia
Asociacion Pr De                   $40,000.00   Corporate Sponsorship
 Gastroenterologia
Asociacion Pr De                   $30,000.00   Corporate Sponsorship
 Gastroenterologia
Asociacion Puertorriquena           $2,500.00   Corporate Sponsorship
 De Ayuda Al Paciente De
 Psiorasis
Asociacion Puertorriquena          $15,000.00   Corporate Sponsorship
 De Medicina Fisica Y
 Rehabilitacion
Asociacion Puertorriquena           $6,000.00   Corporate Sponsorship
 De Medicina Fisica Y
 Rehabilitacion
Aspen Cancer Conference,            $7,500.00   Educational Grants
 Inc.
Association for Assessment          $5,000.00   Charitable Donation
 And Accreditation of
 Laboratory Animal Care
 International
Association of Physician           $10,000.00   Corporate Sponsorship
 Assistants In Oncology
 Inc.
Association of Women in            $30,000.00   Corporate Sponsorship
 Rheumatology
Association of Women in            $30,000.00   Corporate Sponsorship
 Rheumatology
At Point of Care, LLC             $150,000.00   Educational Grants
Autoimmune Advocacy                 $2,500.00   Corporate Sponsorship
 Alliance
Baehr Challenge Ltd.                $2,500.00   Corporate Sponsorship
Baehr Challenge Ltd.                $4,000.00   Corporate Sponsorship
Balm In Gilead Inc.                $75,000.00   Corporate Sponsorship
Baylor College of Medicine          $5,000.00   Educational Grants
Baylor College of Medicine          $5,000.00   Corporate Sponsorship
Baylor Health Care System          $40,000.00   Fellowships or
 Foundation                                      Scholarships
Baylor Univ Med Ctr.               $40,000.00   Educational Grants
Beth Israel Deaconess              $35,000.00   Fellowships or
 Medical Center                                  Scholarships
Beth Israel Deaconess              $40,000.00   Fellowships or
 Medical Center                                  Scholarships
Beth Israel Deaconess              $25,000.00   Fellowships or
 Medical Center                                  Scholarships
Beth Israel Deaconess               $8,000.00   Educational Grants
 Medical Center
Bioconnections LLC                $125,000.00   Corporate Sponsorship
Board of Trustees of The           $40,000.00   Fellowships or
 University of Illinois                          Scholarships
Board of Trustees of The            $1,500.00   Educational Grants
 University of Illinois
Boomer Esiason Foundation          $25,000.00   Corporate Sponsorship
Boomer Esiason Foundation         $400,000.00   Corporate Sponsorship
Borland Groover Foundation          $1,000.00   Corporate Sponsorship
Boston Univ School of              $70,000.00   Educational Grants
 Medicine
Boston Univ School of             $125,000.00   Educational Grants
 Medicine
Boston Univ School of               $1,500.00   Educational Grants
 Medicine
Boston Univ School of               $5,000.00   Corporate Sponsorship
 Medicine
Boston Univ School of              $10,000.00   Educational Grants
 Medicine
Boston University Mdcn            ($3,402.40)   Educational Grants
 Psychtry
Brandeis University                 $1,250.00   Charitable Donation
Breast Friends                      $1,500.00   Corporate Sponsorship
Business Hlth Coalition             $3,300.00   Corporate Sponsorship
 Foundation
Butler University                   $1,250.00   Charitable Donation
California Association for          $1,500.00   Corporate Sponsorship
 Nurse Practitioners
California Healthcare               $1,500.00   Corporate Sponsorship
 Institute
California Life Sciences            $5,000.00   Corporate Sponsorship
 Association
California Life Sciences            $1,500.00   Corporate Sponsorship
 Association
California Socty of                $10,000.00   Corporate Sponsorship
 Dermatology & Dermatology
 Surgry
Cancer Care                         $2,500.00   Educational Grants
Cancer Care                         $2,500.00   Educational Grants
Cancer Care                       ($2,500.00)   Educational Grants
Cancer Care                        $25,000.00   Educational Grants
Cancer Care                        $25,000.00   Educational Grants
Cancer Molecular                    $5,000.00   Educational Grants
 Therapeutics Research
 Association
Capital Meeting Planning            $2,000.00   Educational Grants
 Inc.
Caribe Gyn, Inc.                    $5,000.00   Corporate Sponsorship
Casa Lake County                   $10,000.00   Corporate Sponsorship
Catholic Charities of The           $8,500.00   Corporate Sponsorship
 Archdiocese of Chicago
Cedars-Sinai Medical Center        $40,000.00   Fellowships or
                                                 Scholarships
Cedars-Sinai Medical Center       ($4,000.00)   Educational Grants
Central Florida Pharmacy           $15,000.00   Patient Support
 Council
Central Savannah River Area         $1,000.00   Corporate Sponsorship
 Csra Parkinson Support
 Group
Chicago Help Initiative             $7,500.00   Charitable Donation
Childhood Arthritis And            $35,000.00   Corporate Sponsorship
 Rheumatology Research
 Alliance Carra
Children And Arthritis,             $4,500.00   Charitable Donation
 Inc.
Childrens Digestive Hlth           $40,000.00   Fellowships or
 And Nutrition Foundation                        Scholarships
Childrens Digestive Hlth         ($40,000.00)   Fellowships or
 And Nutrition Foundation                        Scholarships
Childrens Digestive Hlth           $56,000.00   Educational Grants
 And Nutrition Foundation
Childrens Digestive Hlth           $10,000.00   Corporate Sponsorship
 And Nutrition Foundation
Childrens Digestive Hlth            $2,500.00   Corporate Sponsorship
 And Nutrition Foundation
Chimp Haven, Inc.                  $25,000.00   Charitable Donation
Chronic Liver Disease           $1,000,000.00   Educational Grants
 Foundation
Chronic Liver Disease             $364,315.00   Educational Grants
 Foundation
Chronic Liver Disease           $1,513,875.00   Educational Grants
 Foundation
Chronic Liver Disease             ($2,700.00)   Educational Grants
 Foundation
Chronic Liver Disease             ($9,044.17)   Educational Grants
 Foundation
Chronic Liver Disease             ($9,045.00)   Educational Grants
 Foundation
Chronic Liver Disease              $27,500.00   Corporate Sponsorship
 Foundation
Chronic Lymphoytic Leukemia        $25,000.00   Charitable Donation
 Society, Inc.
Chronic Lymphoytic Leukemia        $25,000.00   Educational Grants
 Society, Inc.
Chronic Lymphoytic Leukemia        $10,000.00   Patient Support
 Society, Inc.
Cincinnati Childrens               $40,000.00   Educational Grants
 Hospital
Cincinnati Childrens               $22,500.00   Corporate Sponsorship
 Hospital Medical Center
 Pulmonary Medicine
Cleveland Clinic Foundation         $3,000.00   Educational Grants
Cleveland Clinic Foundation        $50,000.00   Fellowships or
                                                 Scholarships
Cleveland Clinic Foundation        $40,000.00   Fellowships or
                                                 Scholarships
Cleveland Clinic Minority           $5,000.00   Educational Grants
 Men's Health Center
Cleveland Clnc Educational          ($542.72)   Educational Grants
 Foundation The
Cleveland Clnc Educational         $50,000.00   Educational Grants
 Foundation The
Cleveland Clnc Educational         $50,000.00   Educational Grants
 Foundation The
Cleveland Clnc Educational        ($6,109.89)   Educational Grants
 Foundation The
Cleveland Clnc Educational        ($1,147.40)   Educational Grants
 Foundation The
Clinical Care Options, LLC         $75,000.00   Educational Grants
Clinical Care Options, LLC        $100,000.00   Educational Grants
Clinical Care Options, LLC         $75,000.00   Educational Grants
Clinical Care Options, LLC        $100,000.00   Educational Grants
Cll Global Research                $15,000.00   Educational Grants
 Foundation
Cll Global Research                $25,000.00   Educational Grants
 Foundation
Coalition for Prevention of         $5,000.00   Corporate Sponsorship
 Colorectal Cancer In
 Puerto Rico
Coalition for Prevention of         $3,000.00   Corporate Sponsorship
 Colorectal Cancer In
 Puerto Rico
Colegio De Medicos                 $20,000.00   Educational Grants
 Cirujanos De Puerto Rico
Columbia Univ Med Ctr               $1,250.00   Charitable Donation
Community Health                   $10,000.00   Corporate Sponsorship
Community Health                   $10,000.00   Corporate Sponsorship
Community Health                   $10,000.00   Corporate Sponsorship
Community Health And Men's          $5,000.00   Patient Support
 Promotion Summit
Community Initiatives               $5,000.00   Corporate Sponsorship
Community Initiatives              $57,000.00   Corporate Sponsorship
Community Initiatives              $50,000.00   Corporate Sponsorship
Community Liver Alliance            $5,000.00   Corporate Sponsorship
Complete Conference Mgmt            ($916.00)   Educational Grants
Connect1D                           $2,500.00   Corporate Sponsorship
Connecticut Academy of              $1,700.00   Corporate Sponsorship
 Physician Assistants
Connecticut Advocates for             $500.00   Corporate Sponsorship
 Parkinsons Inc.
Connecting To Cure Crohns           $5,000.00   Corporate Sponsorship
 And Colitis
Consortium of Multiple             $25,000.00   Educational Grants
 Sclerosis Centers
Continuing Education              $400,000.00   Educational Grants
 Alliance, LLC
Continuing Education              $350,000.00   Educational Grants
 Alliance, LLC
Continuing Education              ($1,972.99)   Educational Grants
 Alliance, LLC
Continuing Education              ($5,392.00)   Educational Grants
 Alliance, LLC
Continuing Education                ($723.11)   Educational Grants
 Alliance, LLC
Continuing Education              ($3,353.94)   Educational Grants
 Alliance, LLC
Continuing Education              $439,195.00   Educational Grants
 Alliance, LLC
Continuing Education              ($1,553.15)   Educational Grants
 Alliance, LLC
Continuing Education              ($1,523.00)   Educational Grants
 Alliance, LLC
Continuing Education                ($567.24)   Educational Grants
 Alliance, LLC
Cope Coalition On Positive         $20,000.00   Corporate Sponsorship
 Health Empowerment
Cope Coalition On Positive         $15,000.00   Corporate Sponsorship
 Health Empowerment
Core Foundation                    $10,000.00   Corporate Sponsorship
Cornell University Weill            $2,500.00   Educational Grants
 Cornell Medical College
Cornell University Weill            $2,500.00   Educational Grants
 Cornell Medical College
Cornerstones Health Inc.           $90,000.00   Educational Grants
Cornerstones Health Inc.         ($20,375.00)   Educational Grants
Cornerstones Health Inc.           $75,000.00   Educational Grants
Crape Myrtle Festival                 $300.00   Corporate Sponsorship
Creighton University                $7,500.00   Educational Grants
Crohn's and Colitis               $400,000.00   Corporate Sponsorship
 Foundation of America,
 Inc.
Crohn's and Colitis                $22,500.00   Corporate Sponsorship
 Foundation of America,
 Inc.
Crohn's and Colitis                 $5,000.00   Corporate Sponsorship
 Foundation of America,
 Inc.
Crohn's and Colitis             $1,200,000.00   Educational Grants
 Foundation of America,
 Inc.
Crohn's and Colitis               $180,000.00   Educational Grants
 Foundation of America,
 Inc.
Crohn's and Colitis                 $5,000.00   Corporate Sponsorship
 Foundation of America,
 Inc.
Crohn's and Colitis                 ($265.00)   Educational Grants
 Foundation of America,
 Inc.
Crohn's and Colitis                $50,160.00   Corporate Sponsorship
 Foundation of America,
 Inc.
Crohn's and Colitis                 $3,000.00   Corporate Sponsorship
 Foundation of America,
 Inc.
Crohn's and Colitis                 $2,500.00   Corporate Sponsorship
 Foundation of America,
 Inc.
Crohn's and Colitis                 $1,000.00   Corporate Sponsorship
 Foundation of America,
 Inc.
Crohn's and Colitis                $25,000.00   Charitable Donation
 Foundation of America,
 Inc.
Crohn's and Colitis                $25,000.00   Charitable Donation
 Foundation of America,
 Inc.
Crohn's and Colitis                $90,000.00   Corporate Sponsorship
 Foundation of America,
 Inc.
Crohn's and Colitis                $35,000.00   Educational Grants
 Foundation of America,
 Inc.
Crohn's and Colitis                 $2,500.00   Corporate Sponsorship
 Foundation of America,
 Inc.
Crohn's and Colitis                 $5,000.00   Corporate Sponsorship
 Foundation of America,
 Inc.
Crohn's and Colitis                 $1,500.00   Corporate Sponsorship
 Foundation of America,
 Inc.
Crohn's and Colitis                 $5,000.00   Corporate Sponsorship
 Foundation of America,
 Inc.
Crohn's and Colitis                $10,000.00   Corporate Sponsorship
 Foundation of America,
 Inc.
Crohn's and Colitis               $100,000.00   Fellowships or
 Foundation of America,                          Scholarships
 Inc.
Crohn's and Colitis                $32,500.00   Corporate Sponsorship
 Foundation of America,
 Inc.
Crohn's and Colitis                $10,000.00   Corporate Sponsorship
 Foundation of America,
 Inc.
Crohn's and Colitis                 $1,000.00   Corporate Sponsorship
 Foundation of America,
 Inc.
Crohn's and Colitis                 $1,500.00   Corporate Sponsorship
 Foundation of America,
 Inc.
Crohn's and Colitis                $90,000.00   Corporate Sponsorship
 Foundation of America,
 Inc.
Crohn's and Colitis                $10,000.00   Corporate Sponsorship
 Foundation of America,
 Inc.
Crohn's and Colitis               $400,000.00   Corporate Sponsorship
 Foundation of America,
 Inc.
Crohn's and Colitis                $22,500.00   Corporate Sponsorship
 Foundation of America,
 Inc.
Culinary Care                       $2,500.00   Corporate Sponsorship
Curatio Cme Inst                  ($3,261.00)   Educational Grants
Curatio Cme Inst                    ($180.00)   Educational Grants
Curatio Cme Inst                 ($50,000.00)   Educational Grants
Curatio Cme Inst                  ($8,855.73)   Educational Grants
Cure CF                               $500.00   Corporate Sponsorship
Cystic Fibrosis Foundation         $10,000.00   Corporate Sponsorship
Cystic Fibrosis Foundation          $5,000.00   Corporate Sponsorship
Cystic Fibrosis Foundation          $2,500.00   Corporate Sponsorship
Cystic Fibrosis Foundation          $3,000.00   Corporate Sponsorship
Cystic Fibrosis Foundation          $1,000.00   Corporate Sponsorship
Cystic Fibrosis Foundation          $1,500.00   Corporate Sponsorship
Cystic Fibrosis Foundation          $3,750.00   Corporate Sponsorship
Cystic Fibrosis Foundation        $500,000.00   Corporate Sponsorship
Cystic Fibrosis Foundation          $2,500.00   Corporate Sponsorship
Cystic Fibrosis Foundation        $100,000.00   Charitable Donation
Cystic Fibrosis Foundation          $2,500.00   Corporate Sponsorship
Cystic Fibrosis Foundation          $2,000.00   Corporate Sponsorship
Cystic Fibrosis Foundation          $1,500.00   Corporate Sponsorship
Cystic Fibrosis Foundation          $1,000.00   Corporate Sponsorship
Cystic Fibrosis Foundation          $1,000.00   Corporate Sponsorship
Cystic Fibrosis Foundation          $2,500.00   Corporate Sponsorship
Cystic Fibrosis Foundation          $2,000.00   Corporate Sponsorship
Cystic Fibrosis Foundation          $1,000.00   Corporate Sponsorship
Cystic Fibrosis Foundation          $5,000.00   Corporate Sponsorship
Cystic Fibrosis Foundation          $7,500.00   Corporate Sponsorship
Cystic Fibrosis Foundation          $3,000.00   Corporate Sponsorship
Cystic Fibrosis Foundation          $1,000.00   Corporate Sponsorship
Cystic Fibrosis Foundation         $10,000.00   Corporate Sponsorship
Cystic Fibrosis Foundation          $1,500.00   Corporate Sponsorship
Cystic Fibrosis Foundation         $50,000.00   Corporate Sponsorship
Cystic Fibrosis Foundation          $3,500.00   Corporate Sponsorship
Cystic Fibrosis Foundation          $1,500.00   Corporate Sponsorship
Cystic Fibrosis Foundation          $1,000.00   Corporate Sponsorship
Cystic Fibrosis Foundation          $2,000.00   Corporate Sponsorship
Cystic Fibrosis Foundation          $2,000.00   Corporate Sponsorship
Cystic Fibrosis Foundation          $1,000.00   Corporate Sponsorship
Cystic Fibrosis Foundation          $2,500.00   Corporate Sponsorship
Cystic Fibrosis Foundation          $2,500.00   Corporate Sponsorship
Cystic Fibrosis Foundation         $25,000.00   Corporate Sponsorship
Cystic Fibrosis Foundation         $15,000.00   Corporate Sponsorship
Cystic Fibrosis Foundation          $2,500.00   Corporate Sponsorship
Cystic Fibrosis Foundation          $1,000.00   Corporate Sponsorship
Cystic Fibrosis Foundation            $750.00   Corporate Sponsorship
Cystic Fibrosis Foundation          $1,000.00   Corporate Sponsorship
Cystic Fibrosis Foundation          $3,000.00   Corporate Sponsorship
Cystic Fibrosis Foundation          $2,000.00   Corporate Sponsorship
Cystic Fibrosis Foundation          $3,750.00   Corporate Sponsorship
Cystic Fibrosis Foundation        $750,000.00   Corporate Sponsorship
Cystic Fibrosis Foundation          $1,500.00   Corporate Sponsorship
Cystic Fibrosis Foundation         $16,000.00   Corporate Sponsorship
Cystic Fibrosis Foundation          $1,000.00   Corporate Sponsorship
Cystic Fibrosis Foundation          $2,500.00   Corporate Sponsorship
Cystic Fibrosis Foundation          $2,500.00   Corporate Sponsorship
Cystic Fibrosis Foundation          $2,500.00   Corporate Sponsorship
Cystic Fibrosis Foundation          $2,500.00   Corporate Sponsorship
Cystic Fibrosis Foundation          $2,500.00   Corporate Sponsorship
Cystic Fibrosis Foundation          $2,500.00   Corporate Sponsorship
Cystic Fibrosis Research            $5,000.00   Corporate Sponsorship
 Fund Emily's Entourage
Cystic Fibrosis Research            $1,250.00   Corporate Sponsorship
 Inc.
Cystic Fibrosis Research            $3,000.00   Corporate Sponsorship
 Inc.
Cystic Fibrosis Research           $15,000.00   Corporate Sponsorship
 Inc.
Cystic Fibrosis Research           $10,000.00   Corporate Sponsorship
 Inc.
Dallas Fort Worth Business          $5,000.00   Corporate Sponsorship
 Group on Health
Dava Oncology LP                   $95,000.00   Corporate Sponsorship
Davis Phinney Foundation           $30,000.00   Educational Grants
Davis Phinney Foundation           $30,000.00   Educational Grants
Davis Phinney Foundation           $40,000.00   Patient Support
Dermatology Education              $30,000.00   Corporate Sponsorship
 Foundation
Dermatology Foundation             $40,000.00   Fellowships or
                                                 Scholarships
Dermatology Foundation            $135,000.00   Charitable Donation
Dermatology Foundation             $50,000.00   Corporate Sponsorship
Dermatology Nurses                 $15,000.00   Educational Grants
 Association
Dermatology Nurses                 $23,270.00   Corporate Sponsorship
 Association
Dermatology Nurses                 $25,850.00   Corporate Sponsorship
 Association
Desert Aids Project Inc.            $2,000.00   Corporate Sponsorship
Digestive Disease Week             $55,000.00   Corporate Sponsorship
Digestive Disease Week              $3,500.00   Corporate Sponsorship
Digestive Health Foundation        $25,000.00   Corporate Sponsorship
Duke University                    $40,000.00   Fellowships or
                                                 Scholarships
Duke University                     ($780.00)   Educational Grants
Duke University Medical            $10,000.00   Fellowships or
 Center                                          Scholarships
East Hawaii IPA                     $8,000.00   Corporate Sponsorship
Efficient Collaborative            $28,100.00   Corporate Sponsorship
 Retail Marketing
Eicosanoid Research                 $2,000.00   Educational Grants
 Foundation
El Centro Regional Medical          $5,000.00   Corporate Sponsorship
 Center Foundation
El Centro Regional Medical          $5,000.00   Corporate Sponsorship
 Center Foundation
Elsevier Inc.                     $150,000.00   Educational Grants
Emory University                   $10,000.00   Corporate Sponsorship
Emory University                    $2,000.00   Corporate Sponsorship
Emory University                   $10,000.00   Corporate Sponsorship
Emory University School of         $25,000.00   Educational Grants
 Medicine
Employers Health Coalition          $4,000.00   Corporate Sponsorship
 Inc.
Endocrine Society                  $10,000.00   Corporate Sponsorship
Endocrine Society                  $15,000.00   Educational Grants
Endometriosis Foundation of         $2,500.00   Corporate Sponsorship
 America
Epilepsy Foundation                $15,000.00   Charitable Donation
Erie Family Health Center           $5,000.00   Sponsorship
                                             Corporate
Escuela De Medicina De              $8,000.00   Educational Grants
 Ponce
Escuela De Medicina San            $40,000.00   Fellowships or
 Juan Bautista                                   Scholarships
Evergreen Foundation of               $750.00   Corporate Sponsorship
 Western New York
Excellence In Rheumatology        $100,000.00   Corporate Sponsorship
 Education LLC
Facing Our Risk of Cancer          $15,000.00   Educational Grants
 Empowerement Force
Federation of American              $5,000.00   Corporate Sponsorship
 Societies for Experimental
 Biology
Federation of American              $1,500.00   Educational Grants
 Societies for Experimental
 Biology
Federation of American              $1,500.00   Educational Grants
 Societies for Experimental
 Biology
Federation of American              $1,500.00   Educational Grants
 Societies for Experimental
 Biology
Federation of American              $1,500.00   Educational Grants
 Societies for Experimental
 Biology
Federation of Clinical             $18,000.00   Educational Grants
 Immunology Societies
Federation of Clinical             $15,000.00   Educational Grants
 Immunology Societies
Florida Health Care                $10,000.00   Corporate Sponsorship
 Coalition
Florida Health Care                 $4,500.00   Corporate Sponsorship
 Coalition
Florida Society of                 $25,000.00   Corporate Sponsorship
 Rheumatology
Focus Medical                     $150,000.00   Corporate Sponsorship
 Communications LLC
Food Outreach                      $10,000.00   Corporate Sponsorship
force--Facing Our Risk of           $5,000.00   Corporate Sponsorship
 Cancer Emp
Foundation for Anesthesia          $15,000.00   Fellowships or
 Education And Research                          Scholarships
Foundation for Arthritis            $5,500.00   Corporate Sponsorship
 Treatment
Foundation for The National        $10,000.00   Corporate Sponsorship
 Institutes of Health
Foundation for Veterans            $25,000.00   Corporate Sponsorship
 Health Care
Foundation of Consortium of         $8,000.00   Charitable Donation
 Multiple Sclerosis Centers
 Cmsc
Foundcare Inc.                      $2,500.00   Corporate Sponsorship
Foundcare Inc.                      $2,500.00   Corporate Sponsorship
Friends of Cancer Research         $30,000.00   Corporate Sponsorship
Friends of Parkinsons               $2,500.00   Corporate Sponsorship
Friends of Prentice                $25,000.00   Charitable Donation
Fundacion De Investigacion         $25,000.00   Educational Grants
Gastro Intestinal Research         $50,000.00   Corporate Sponsorship
 Foundation
Gastro Intestinal Research         $25,000.00   Corporate Sponsorship
 Foundation
Gastrointestinal And Liver         $75,000.00   Educational Grants
 Association of The
 Americas Inc.
Gateway for Cancer Research         $6,000.00   Corporate Sponsorship
General Hospital                   $10,000.00   Educational Grants
 Corporation
Georgia Dermatology                 $7,500.00   Corporate Sponsorship
 Physician Assistants
Georgia Dermatology                $15,000.00   Corporate Sponsorship
 Physician Assistants
Georgia Health Sciences             $1,500.00   Educational Grants
 Foundation Inc.
Georgia Prostate Cancer             $5,000.00   Patient Support
 Coalition
Georgia Society of                  $3,000.00   Corporate Sponsorship
 Dermatology And
 Dermatologic Surgery
Gilda's Club Chicago               $25,000.00   Corporate Sponsorship
Global Academy for Medical         $72,000.00   Corporate Sponsorship
 Education
Global Academy for Medical         $35,000.00   Corporate Sponsorship
 Education
Global Academy for Medical         $18,000.00   Corporate Sponsorship
 Education
Global Academy for Medical         $72,000.00   Corporate Sponsorship
 Education
Global Academy for Medical         $72,000.00   Corporate Sponsorship
 Education
Global Academy for Medical         $45,000.00   Corporate Sponsorship
 Education
Global Alliance for Patient        $30,000.00   Corporate Sponsorship
 Access
Global Alliance for Patient        $50,000.00   Corporate Sponsorship
 Access
Global Alliance for Patient        $50,000.00   Corporate Sponsorship
 Access
Global Alliance for Patient       $250,000.00   Educational Grants
 Access
Global Healthy Living              $24,000.00   Corporate Sponsorship
 Foundation
Global Healthy Living              $25,000.00   Corporate Sponsorship
 Foundation
Gordon Research Conferences         $1,500.00   Educational Grants
Gordon Research Conferences         $1,500.00   Educational Grants
Gordon Research Conferences         $1,500.00   Educational Grants
Gordon Research Conferences         $1,500.00   Educational Grants
Gordon Research Conferences         $2,000.00   Educational Grants
Gordon Research Conferences         $2,500.00   Educational Grants
Gordon Research Conferences         $2,000.00   Educational Grants
Gordon Research Conferences         $1,500.00   Educational Grants
Gordon Research Conferences         $1,500.00   Educational Grants
Gordon Research Conferences         $1,500.00   Educational Grants
Gordon Research Conferences         $1,500.00   Educational Grants
Gordon Research Conferences         $1,000.00   Educational Grants
Gospel Heritage Foundation         $10,000.00   Corporate Sponsorship
Great Lakes Chapter of The          $1,000.00   Corporate Sponsorship
 American Society for
 Pharmacology And
 Experimental Therapeutics
Group of Research And              $15,000.00   Corporate Sponsorship
 Assessment of Psoriasis
 And Psoriatic Arthritis
Grupo De Apoyo De Ninos Y           $3,000.00   Corporate Sponsorship
 Adolescentes Con
 Reumatologia
Gynecologic Oncology Group         $25,000.00   Educational Grants
Gynecologic Oncology Group         $25,000.00   Educational Grants
Heals of The South, Inc.--          $5,000.00   Charitable Donation
 Hepatitis Education
 Awareness And Liver
 Support
Health Action Council Ohio          $3,780.00   Corporate Sponsorship
Healthcare 21 Business              $5,000.00   Corporate Sponsorship
 Coalition
Healthcare 21 Business              $5,000.00   Corporate Sponsorship
 Coalition
Healthcare Financial               $50,000.00   Corporate Sponsorship
 Management Association
 Hfma
Heather Robidoux                    $7,500.00   Corporate Sponsorship
Heb Grocery Company LP             $10,000.00   Corporate Sponsorship
Hep C Connection                   $75,000.00   Patient Support
Hep C Connection                    $5,000.00   Corporate Sponsorship
Hepatitis Education Project        $75,000.00   Charitable Donation
Hepatitis Education Project        $50,000.00   Corporate Sponsorship
Herbert Kosten Pancreatic           $2,000.00   Corporate Sponsorship
 Cancer Charitable Fund
Hitchcock Foundation               $25,000.00   Educational Grants
Hiv Treaters Med Asoc of           $10,000.00   Educational Grants
 Puerto Rico
HMP Communications LLC             $40,000.00   Corporate Sponsorship
Honor Health Virginia G               $800.00   Corporate Sponsorship
 Piper Cancer Center
Hope Foundation The                $20,000.00   Educational Grants
Houston Area Parkinson              $2,500.00   Corporate Sponsorship
 Society
Howard Brown Health Center         $20,000.00   Corporate Sponsorship
Howard Hanna Children's            $10,000.00   Charitable Donation
 Free Care Fund
Hubbard Street Dance               $10,000.00   Educational Grants
 Chicago
Hughes Healthcare                 $177,550.00   Educational Grants
 Disparities Group
Human Growth Foundation             $5,000.00   Corporate Sponsorship
Human Growth Foundation             $4,000.00   Corporate Sponsorship
Humboldt--Del Norte County          $4,000.00   Educational Grants
 Med Socty
Hyacinth Aids Foundation            $5,000.00   Corporate Sponsorship
Illinois African American          $10,000.00   Corporate Sponsorship
 Coalition
Illinois African American          $10,000.00   Corporate Sponsorship
 Coalition
Imedex, LLC                        $40,000.00   Educational Grants
Imedex, LLC                        $30,000.00   Educational Grants
Imedex, LLC                        $40,000.00   Educational Grants
Imedex, LLC                        $15,000.00   Corporate Sponsorship
Imedex, LLC                        $50,000.00   Educational Grants
Imedex, LLC                        $75,000.00   Educational Grants
Indiana University                  $4,100.00   Fellowships or
                                                 Scholarships
Infant Welfare Society of          $10,000.00   Charitable Donation
 Chicago
Infectious Diseases Society        $25,000.00   Charitable Donation
 of America
Infectious Diseases Society        $50,000.00   Educational Grants
 of America
Integrated Benefits                $25,000.00   Corporate Sponsorship
 Institute Inc.
Integrated Benefits                $25,000.00   Corporate Sponsorship
 Institute Inc.
Integrated Medical                 $35,000.00   Charitable Donation
 Foundation
Integrated Medical                  $2,000.00   Corporate Sponsorship
 Foundation
Integrated Medical                  $2,000.00   Corporate Sponsorship
 Foundation
Integrated Medical                  $1,000.00   Corporate Sponsorship
 Foundation
Interfaith House                    $2,000.00   Charitable Donation
International Aids Socty--        $200,000.00   Educational Grants
 USA
International Aids Socty--         $80,000.00   Educational Grants
 USA
International Aids Socty--         $75,000.00   Educational Grants
 USA
International Asoc for The          $2,500.00   Corporate Sponsorship
 Study of Lung Cancer IASLC
International Association          $10,000.00   Educational Grants
 of Providers of Aids Care
International Association          $10,000.00   Educational Grants
 of Providers of Aids Care
International Chinese               $3,000.00   Educational Grants
 Statistical Association
International Dermatology          $70,000.00   Corporate Sponsorship
 Outcome Measures
International Foot And              $2,000.00   Corporate Sponsorship
 Ankle Foundation
International League of            $20,000.00   Charitable Donation
 Association for
 Rheumatology
International Liver                $10,000.00   Educational Grants
 Transplantation Society
International Liver                $40,000.00   Educational Grants
 Transplantation Society
International Medical Corps         $5,000.00   Corporate Sponsorship
International Psoriasis           $100,000.00   Corporate Sponsorship
 Council
International Psoriasis            $50,000.00   Corporate Sponsorship
 Council
International Psoriasis            $50,000.00   Corporate Sponsorship
 Council
International Psoriasis            $50,000.00   Corporate Sponsorship
 Council
International Society for           $3,000.00   Educational Grants
 The Study of Xenbiotics
International Society of            $2,000.00   Educational Grants
 Biopharmaceutical
 Statistics
International Society of            $1,500.00   Educational Grants
 Heterocyclic Chemistry
Iowa Pharmacy Association           $5,000.00   Corporate Sponsorship
Johns Hopkins Univ School          $75,000.00   Educational Grants
 of Medicine
Johns Hopkins Univ School          $25,000.00   Corporate Sponsorship
 of Medicine
Johns Hopkins Univ School          $40,000.00   Fellowships or
 of Medicine                                     Scholarships
Johns Hopkins Univ School         ($5,646.02)   Educational Grants
 of Medicine
Johns Hopkins Univ School          $46,213.00   Educational Grants
 of Medicine
Johns Hopkins Univ School          $50,000.00   Educational Grants
 of Medicine
JWC Covenant, Inc.                 $20,000.00   Educational Grants
JWC Covenant, Inc.                 $25,000.00   Corporate Sponsorship
JWC Covenant, Inc.                  $2,500.00   Corporate Sponsorship
Kansas University Endowment           $500.00   Corporate Sponsorship
 Association
Keck Medical Center of USC         $25,000.00   Educational Grants
Kelsey Research Foundation         $35,000.00   Fellowships or
                                                 Scholarships
Ken Zebrowski Memorial Walk         $2,000.00   Corporate Sponsorship
Kidney Disease Improving          $200,000.00   Corporate Sponsorship
 Global Outcomes
Laboratorio Clinico Toledo            $900.00   Patient Support
Laboratorio Clinico Toledo          $1,365.00   Patient Support
Laboratorio Clinico Toledo          $1,200.00   Patient Support
Laboratorio Clinico Toledo            $615.00   Patient Support
Laboratorio Clinico Toledo            $720.00   Patient Support
Laboratorio Clinico Toledo          $1,275.00   Patient Support
Laboratorio Clinico Toledo          $1,365.00   Patient Support
Laboratorio Clinico Toledo          $1,365.00   Patient Support
Laboratorio Clinico Toledo          $2,040.00   Patient Support
Laboratorio Clinico Toledo          $1,500.00   Patient Support
Laboratorio Clinico Toledo          $1,500.00   Patient Support
Laboratorio Clinico Toledo          $1,365.00   Patient Support
Laboratorio Clinico Toledo            $945.00   Patient Support
Laboratorio Clinico Toledo          $1,320.00   Patient Support
Laboratorio Clinico Toledo          $3,600.00   Patient Support
Laboratorio Clinico Toledo          $1,800.00   Patient Support
Laboratorio Clinico Toledo          $1,500.00   Patient Support
Laboratorio Clinico Toledo          $1,245.00   Patient Support
Laboratorio Clinico Toledo          $4,125.00   Patient Support
Laboratorio Clinico Toledo          $2,220.00   Patient Support
Laboratorio Clinico Toledo          $2,160.00   Patient Support
Laboratorio Clinico Toledo          $1,605.00   Patient Support
Laboratorio Clinico Toledo          $2,040.00   Patient Support
Laboratorio Clinico Toledo          $1,500.00   Patient Support
Laboratorio Clinico Toledo          $1,500.00   Patient Support
Laboratorio Clinico Toledo          $1,455.00   Patient Support
Laboratorio Clinico Toledo          $1,650.00   Patient Support
Laboratorio Clinico Toledo          $1,365.00   Patient Support
Laboratorio Clinico Toledo            $360.00   Patient Support
Laboratorio Clinico Toledo            $876.00   Patient Support
Laboratorio Clinico Toledo          $1,110.00   Patient Support
Laboratorio Clinico Toledo          $1,470.00   Patient Support
Laboratorio Clinico Toledo          $2,715.00   Patient Support
Laboratorio Clinico Toledo          $1,140.00   Patient Support
Laboratorio Clinico Toledo          $1,770.00   Patient Support
Laboratorio Clinico Toledo          $1,500.00   Patient Support
Laboratorio Clinico Toledo          $1,485.00   Patient Support
Laboratorio Clinico Toledo          $1,455.00   Patient Support
Laboratorio Clinico Toledo          $1,335.00   Patient Support
Laboratorio Clinico Toledo          $1,095.00   Patient Support
Laboratorio Clinico Toledo          $1,500.00   Patient Support
Laboratorio Clinico Toledo          $1,500.00   Patient Support
Laboratorio Clinico Toledo          $1,380.00   Patient Support
Laboratorio Clinico Toledo          $1,500.00   Patient Support
Laboratorio Clinico Toledo          $1,215.00   Patient Support
Laboratorio Clinico Toledo            $975.00   Patient Support
Laboratorio Clinico Toledo            $945.00   Patient Support
Laboratorio Clinico Toledo            $825.00   Patient Support
Laboratorio Clinico Toledo          $1,140.00   Patient Support
Laboratorio Clinico Toledo          $2,730.00   Patient Support
Laboratorio Clinico Toledo          $1,065.00   Patient Support
Laboratorio Clinico Toledo            $990.00   Patient Support
Laboratorio Clinico Toledo          $1,980.00   Patient Support
Laboratorio Clinico Toledo          $2,610.00   Patient Support
Laboratorio Clinico Toledo          $1,650.00   Patient Support
Laboratorio Clinico Toledo          $2,190.00   Patient Support
Laboratorio Clinico Toledo            $855.00   Patient Support
Laboratorio Clinico Toledo          $1,785.00   Patient Support
Laboratorio Clinico Toledo            $276.00   Patient Support
Laboratorio Clinico Toledo          $1,680.00   Patient Support
Laboratorio Clinico Toledo            $510.00   Patient Support
Laboratorio Clinico Toledo          $1,200.00   Patient Support
Laboratorio Clinico Toledo            $525.00   Patient Support
Laboratorio Clinico Toledo          $1,335.00   Patient Support
Laboratorio Clinico Toledo          $1,650.00   Patient Support
Laboratorio Clinico Toledo            $630.00   Patient Support
Laboratorio Clinico Toledo            $990.00   Patient Support
Laboratorio Clinico Toledo          $1,020.00   Patient Support
Laboratorio Clinico Toledo          $1,275.00   Patient Support
Laboratorio Clinico Toledo          $1,395.00   Patient Support
Laboratorio Clinico Toledo            $315.00   Patient Support
Laboratorio Clinico Toledo          $1,500.00   Patient Support
Laboratorio Clinico Toledo          $1,290.00   Patient Support
Laboratorio Clinico Toledo          $1,275.00   Patient Support
Laboratorio Clinico Toledo            $525.00   Patient Support
Laboratorio Clinico Toledo            $510.00   Patient Support
Laboratorio Clinico Toledo            $315.00   Patient Support
Laboratorio Clinico Toledo          $1,035.00   Patient Support
Laboratorio Clinico Toledo            $240.00   Patient Support
Laboratorio Clinico Toledo          $1,065.00   Patient Support
Laboratorio Clinico Toledo            $660.00   Patient Support
Laboratorio Clinico Toledo          $1,500.00   Patient Support
Laboratorio Clinico Toledo            $900.00   Patient Support
Laboratorio Clinico Toledo            $900.00   Patient Support
Laboratorio Clinico Toledo            $810.00   Patient Support
Laboratorio Clinico Toledo          $1,020.00   Patient Support
Laboratorio Clinico Toledo          $1,200.00   Patient Support
Laboratorio Clinico Toledo          $3,000.00   Patient Support
Laboratorio Clinico Toledo          $1,500.00   Patient Support
Laboratorio Clinico Toledo          $2,400.00   Patient Support
Laboratorio Clinico Toledo            $465.00   Patient Support
Laboratorio Clinico Toledo          $1,500.00   Patient Support
Laboratorio Clinico Toledo          $1,410.00   Patient Support
Laboratorio Clinico Toledo            $825.00   Patient Support
Laboratorio Clinico Toledo            $525.00   Patient Support
Laboratorio Clinico Toledo            $444.00   Patient Support
Laboratorio Clinico Toledo            $645.00   Patient Support
Laboratorio Clinico Toledo          $1,125.00   Patient Support
Laboratorio Clinico Toledo          $1,185.00   Patient Support
Laboratorio Clinico Toledo          $1,320.00   Patient Support
Laboratorio Clinico Toledo          $2,160.00   Patient Support
Laboratorio Clinico Toledo          $1,740.00   Patient Support
Lake County Haven                  $10,000.00   Corporate Sponsorship
Large Urology Group                $20,000.00   Corporate Sponsorship
 Practice Association
Large Urology Group                $15,000.00   Corporate Sponsorship
 Practice Association
Large Urology Group                $66,400.00   Corporate Sponsorship
 Practice Association
Large Urology Group                $25,000.00   Corporate Sponsorship
 Practice Association
Leading Edge US LLC               $125,000.00   Educational Grants
Leukemia and Lymphoma               $5,000.00   Educational Grants
 Society
Leukemia and Lymphoma               $2,500.00   Educational Grants
 Society
Leukemia and Lymphoma              $15,000.00   Corporate Sponsorship
 Society
Leukemia and Lymphoma             $100,000.00   Corporate Sponsorship
 Society
Leukemia Research                  $10,000.00   Corporate Sponsorship
 Foundation
Leukemia Research                  $10,000.00   Corporate Sponsorship
 Foundation
Leukemia Research                  $20,000.00   Corporate Sponsorship
 Foundation
Leukemia Research                   $5,000.00   Corporate Sponsorship
 Foundation
Life Sciences Foundation           $30,000.00   Charitable Donation
Los Angeles Urological              $8,500.00   Corporate Sponsorship
 Society
Louisiana State Univ Hlth         ($9,779.71)   Fellowships or
 Scnc Ctr                                        Scholarships
Louisiana State Univ Hlth           $1,200.00   Corporate Sponsorship
 Scnc Foundation
Lupus Research Inst Inc.           $50,000.00   Corporate Sponsorship
Magellan Health Services           $35,000.00   Corporate Sponsorship
Main Line Health, Inc.              $2,500.00   Educational Grants
Map International                  $25,000.00   Corporate Sponsorship
Maryland Dermatologic Socty        $75,000.00   Corporate Sponsorship
Massachusetts Biotechnology         $5,000.00   Corporate Sponsorship
 Council
Massachusetts Institute of          $1,250.00   Charitable Donation
 Technology
Massachusetts Institute of          $1,250.00   Charitable Donation
 Technology
Massachusetts Prostate              $5,000.00   Educational Grants
 Cancer Coalition
Massachusetts Public Health         $2,500.00   Corporate Sponsorship
 Association
Massachusetts Public Health         $2,500.00   Corporate Sponsorship
 Association
Massachusetts Society for           $5,000.00   Educational Grants
 Medical Research
Max Foundation                     $45,000.00   Corporate Sponsorship
Medina Community Clinic             $1,000.00   Corporate Sponsorship
Med-IQ, LLC                       $200,000.00   Educational Grants
Med-IQ, LLC                       $156,924.00   Educational Grants
Medscape LLC                      $205,000.00   Educational Grants
Medscape LLC                        $1,000.00   Educational Grants
Medscape LLC                      $175,000.00   Educational Grants
Medscape LLC                      $300,000.00   Educational Grants
Medscape LLC                      $150,000.00   Educational Grants
Medscape LLC                      $150,000.00   Educational Grants
Medscape LLC                       $50,000.00   Educational Grants
Medscape LLC                      $190,000.00   Educational Grants
Medscape LLC                      $250,000.00   Educational Grants
Medscape LLC                       $60,000.00   Educational Grants
Medscape LLC                       $50,000.00   Educational Grants
Medscape LLC                        $8,000.00   Educational Grants
Medscape LLC                      $150,000.00   Educational Grants
Memorial Hermann Foundation        $35,000.00   Fellowships or
                                                 Scholarships
Memphis Business Group on           $5,120.00   Corporate Sponsorship
 Health
Memphis Business Group on           $6,500.00   Corporate Sponsorship
 Health
Men Educating Men, Inc.            $20,000.00   Patient Support
Mercer County Joint Twnshp          ($336.00)   Educational Grants
 Commty Hosp Dba Mercer
 Hlth
Mercer County Joint Twnshp          $3,000.00   Patient Support
 Commty Hosp Dba Mercer
 Hlth
Methodist Hosp The                 $25,000.00   Corporate Sponsorship
Mexican American                    $5,000.00   Corporate Sponsorship
 Legislative Leadership
 Foundation
Michael J Fox Foundation           $69,500.00   Educational Grants
Michael J Fox Foundation           $25,000.00   Corporate Sponsorship
Michael J Fox Foundation           $50,000.00   Corporate Sponsorship
Michael J Fox Foundation            $7,500.00   Corporate Sponsorship
Michigan Parkinson                  $2,000.00   Corporate Sponsorship
 Foundation
Michigan Rheumatism Society        $15,000.00   Corporate Sponsorship
Mid Atlantic Business Group         $7,500.00   Corporate Sponsorship
 Heatlh
Midwest Business Group on           $1,000.00   Corporate Sponsorship
 Health
Midwest Pediatric Endocrine         $6,300.00   Corporate Sponsorship
 Society
Military officers                  $10,000.00   Corporate Sponsorship
 Association of America
 Family Initiative
Minnesota Urological                $2,500.00   Corporate Sponsorship
 Society
Mississippi                         $1,000.00   Corporate Sponsorship
 Gastroenterology Society
Mississippi                         $1,500.00   Corporate Sponsorship
 Gastroenterology Society
Missouri Hepatitis C               $25,000.00   Educational Grants
 Alliance
Missouri Hepatitis C               $25,000.00   Educational Grants
 Alliance
Missouri Hepatitis C               $25,000.00   Charitable Donation
 Alliance
Montefiore Medical Center          $25,000.00   Educational Grants
Montefiore Medical Center          $75,000.00   Educational Grants
Montefiore Medical Center        ($10,457.00)   Educational Grants
Mount Sinai School of               $8,000.00   Corporate Sponsorship
 Medicine
Mount Sinai School of             $250,000.00   Educational Grants
 Medicine
Mount Sinai School of              $15,000.00   Educational Grants
 Medicine
Mount Sinai School of              $40,000.00   Educational Grants
 Medicine
Mount Sinai School of               $5,000.00   Educational Grants
 Medicine
Mount Sinai School of              $20,000.00   Educational Grants
 Medicine
Mount Sinai School of             $200,000.00   Educational Grants
 Medicine
Movement Disorder Socty The       $172,000.00   Corporate Sponsorship
Movement Disorder Socty The       $111,230.00   Educational Grants
Movement Disorder Socty The       $184,500.00   Corporate Sponsorship
Multiple Myeloma Research          $10,000.00   Educational Grants
 Foundation
My Gut Instinct Inc.                $1,500.00   Corporate Sponsorship
National Academy of                $30,000.00   Corporate Sponsorship
 Dermatology Nurse
 Practitioners
National Academy of                $30,000.00   Corporate Sponsorship
 Dermatology Nurse
 Practitioners
National AIDS Treatment           $150,000.00   Patient Support
 Advocacy Project
National AIDS Treatment           $300,000.00   Charitable Donation
 Advocacy Project
National Alliance of Mental         $5,000.00   Corporate Sponsorship
 Illness Michigan
National Alliance of Mental         $2,500.00   Corporate Sponsorship
 Illness Oregon
National Alliance of Mental         $2,500.00   Corporate Sponsorship
 Illness Washington
National Alliance of State         $30,000.00   Corporate Sponsorship
 And Territorial Aids
 Directors
National Alliance of State         $75,000.00   Charitable Donation
 And Territorial Aids
 Directors
National Animal Interest           $20,000.00   Charitable Donation
 Alliance
National Association of            $25,000.00   Corporate Sponsorship
 Latino Elected & Appointed
 officials Educational Fund
National Black Leadership           $6,000.00   Corporate Sponsorship
 Commission on AIDS
National Black Leadership           $5,000.00   Corporate Sponsorship
 Commission on AIDS
National Black Leadership          $14,000.00   Corporate Sponsorship
 Commission on AIDS
National Coalition for             $40,000.00   Corporate Sponsorship
 Cancer
National Coalition for              $2,500.00   Corporate Sponsorship
 Cancer
National Comprehensive             $25,000.00   Corporate Sponsorship
 Cancer Network
National Comprehensive              $7,196.32   Educational Grants
 Cancer Network
National Comprehensive             $50,000.00   Educational Grants
 Cancer Network
National Comprehensive             $50,000.00   Educational Grants
 Cancer Network
National Comprehensive            ($1,824.00)   Educational Grants
 Cancer Network, Inc.
National Family Caregivers         $30,000.00   Corporate Sponsorship
 Association
National Foundation for            $25,000.00   Corporate Sponsorship
 Celiac Awareness
National Hispanic Council          $30,000.00   Corporate Sponsorship
 on Aging
National Kidney Foundation            $500.00   Corporate Sponsorship
National Minority Quality          $20,000.00   Corporate Sponsorship
 forum Inc.
National Minority Quality           $5,000.00   Corporate Sponsorship
 forum Inc
National Multiple Sclerosis        $10,000.00   Corporate Sponsorship
 Society
National Multiple Sclerosis        $10,000.00   Corporate Sponsorship
 Society
National Multiple Sclerosis       $225,000.00   Corporate Sponsorship
 Society
National Pancreas                   $5,000.00   Corporate Sponsorship
 Foundation
National Pancreas                  $75,000.00   Charitable Donation
 Foundation
National Pancreas                  $75,000.00   Educational Grants
 Foundation
National Pancreas                   $6,000.00   Corporate Sponsorship
 Foundation
National Pancreas                  $25,000.00   Corporate Sponsorship
 Foundation
National Pancreas                 $200,000.00   Educational Grants
 Foundation
National Pancreas                   $2,000.00   Corporate Sponsorship
 Foundation
National Pancreas                   $1,000.00   Corporate Sponsorship
 Foundation
National Pancreas                   $1,500.00   Corporate Sponsorship
 Foundation
National Pancreas                   $2,500.00   Corporate Sponsorship
 Foundation
National Pancreas                   $2,500.00   Corporate Sponsorship
 Foundation
National Pancreas                   $2,500.00   Corporate Sponsorship
 Foundation
National Pancreas                   $1,500.00   Corporate Sponsorship
 Foundation
National Pancreas                   $6,000.00   Corporate Sponsorship
 Foundation
National Pancreas                     $500.00   Corporate Sponsorship
 Foundation
National Patient Advocate          $65,000.00   Corporate Sponsorship
 Foundation Inc.
National Psoriasis                 $30,000.00   Patient Support
 Foundation
National Psoriasis                 $15,000.00   Corporate Sponsorship
 Foundation
National Psoriasis                 $25,000.00   Corporate Sponsorship
 Foundation
National Psoriasis                 $40,000.00   Educational Grants
 Foundation
National Psoriasis                 $10,000.00   Corporate Sponsorship
 Foundation
National Psoriasis                $150,000.00   Corporate Sponsorship
 Foundation
National Psoriasis                 $50,000.00   Corporate Sponsorship
 Foundation
National Society for               $50,000.00   Corporate Sponsorship
 Cutaneous Medicine
National Society for              $125,000.00   Corporate Sponsorship
 Cutaneous Medicine
National Society for              $135,000.00   Corporate Sponsorship
 Cutaneous Medicine
Nationwide Childrens Hosp           $7,500.00   Corporate Sponsorship
 Foundation
Natl Commission On                 $20,000.00   Educational Grants
 Correctional Hlth Care
Natl Committee for Quality         $25,000.00   Corporate Sponsorship
 Assurance
Natl Comprehensive Cancer          $40,000.00   Charitable Donation
 Ntwrk
Natl Comprehensive Cancer          $25,000.00   Charitable Donation
 Ntwrk
Natl Multiple Sclerosis            $15,000.00   Corporate Sponsorship
 Socty Greater Illinois
 Chapter
Nebraska Gut Club                     $600.00   Corporate Sponsorship
Neuro Challenge Foundation          $5,000.00   Corporate Sponsorship
 Inc.
Neuropathy Action                   $2,500.00   Corporate Sponsorship
 Foundation
New Jersey Association for          $2,500.00   Educational Grants
 Biomedical Research
New Mexico Parkinsons               $3,000.00   Educational Grants
 Disease Coalition
New York Academy of                 $2,500.00   Educational Grants
 Sciences
New York State Rheumatology        $15,000.00   Corporate Sponsorship
 Society
New York Univ School of            $10,000.00   Educational Grants
 Medicine
New York Univ School of          ($40,000.01)   Fellowships or
 Medicine                                        Scholarships
New York Univ School of            $10,000.00   Educational Grants
 Medicine
Nicole Jarvis Md Parkinsons         $1,000.00   Corporate Sponsorship
 Research Foundation
Nl Communications Inc.             $20,000.00   Educational Grants
Nl Communications Inc.             $20,000.00   Educational Grants
Nl Communications Inc.             $50,000.00   Educational Grants
Nl Communications Inc.             $15,000.00   Educational Grants
North American Ctr for            $350,000.00   Educational Grants
 Continuing Med Education
North American Ctr for             $60,000.00   Educational Grants
 Continuing Med Education
North American Ctr for            $200,000.00   Educational Grants
 Continuing Med Education
North American Ctr for            $200,000.00   Educational Grants
 Continuing Med Education
North American Ctr for            $375,000.00   Educational Grants
 Continuing Med Education
North American Ctr for             $39,500.00   Educational Grants
 Continuing Med Education
North American Ctr for             $88,000.00   Educational Grants
 Continuing Med Education
Northeast Business Group on         $1,000.00   Corporate Sponsorship
 Health
Northeast Business Group on         $5,000.00   Corporate Sponsorship
 Health
Northwest Arthritis and           $120,000.00   Educational Grants
 Osteoporosis Institute
Northwest Arthritis and            $30,000.00   Educational Grants
 Osteoporosis Institute
Northwest Kidney Centers            $2,500.00   Corporate Sponsorship
Northwest Kidney Centers            $2,500.00   Corporate Sponsorship
Northwest Parkinson's               $4,500.00   Educational Grants
 Foundation
Northwest Parkinson's                 $550.00   Corporate Sponsorship
 Foundation
Northwestern University            $40,000.00   Fellowships or
                                                 Scholarships
Northwestern University            $40,000.00   Fellowships or
                                                 Scholarships
Northwestern University             $3,000.00   Educational Grants
Norton Healthcare                   $1,200.00   Corporate Sponsorship
 Foundation
Novation LLC                       $25,000.00   Corporate Sponsorship
Nyu Langone Medical Center          $3,000.00   Corporate Sponsorship
Ochsner Clinic Foundation           $2,000.00   Corporate Sponsorship
Ohio Association of                $10,000.00   Corporate Sponsorship
 Rheumatology
Ohio Gastroenterology               $5,000.00   Corporate Sponsorship
 Society
Oklahoma State Urological          $10,000.00   Corporate Sponsorship
 Association
Oncology Nursing Society            $5,000.00   Educational Grants
One Health Research                $50,000.00   Charitable Donation
Oregon Health And Science           $3,000.00   Corporate Sponsorship
 University
Oregon Health And Science          $12,000.00   Educational Grants
 University
Oregon Health And Science           $5,000.00   Educational Grants
 University
Oregon Health And Science           $3,000.00   Corporate Sponsorship
 University
Oregon State University             $7,500.00   Corporate Sponsorship
 Foundation
Orthopaedic Research                $5,000.00   Educational Grants
 Society
Pacific Dermatologic               $10,000.00   Corporate Sponsorship
 Association
Pacific Dermatologic               $20,000.00   Corporate Sponsorship
 Association
Pancreas Club The                  $10,000.00   Educational Grants
Pancreatic Cancer Action            $3,000.00   Corporate Sponsorship
 Network
Pancreatic Cancer Action            $3,000.00   Corporate Sponsorship
 Network
Pancreatic Cancer Action          $200,000.00   Corporate Sponsorship
 Network
Park Nicollet Foundation            $1,000.00   Corporate Sponsorship
Parkinson Alliance Inc.               $500.00   Corporate Sponsorship
Parkinson Alliance Inc.             $1,000.00   Corporate Sponsorship
Parkinson And Movement              $4,000.00   Corporate Sponsorship
 Disorder Alliance
Parkinson Association of            $2,500.00   Corporate Sponsorship
 Alabama
Parkinson Association of            $1,000.00   Corporate Sponsorship
 The Carolinas
Parkinson Association of            $8,000.00   Patient Support
 The Rockies
Parkinson Council                   $1,000.00   Corporate Sponsorship
Parkinson Foundation of               $500.00   Corporate Sponsorship
 Oklahoma
Parkinson Foundation of             $1,500.00   Corporate Sponsorship
 Oklahoma
Parkinson Foundation of The         $5,000.00   Educational Grants
 National Capital Area
Parkinson Foundation of The         $2,500.00   Corporate Sponsorship
 National Capital Area
Parkinson Foundation                $5,000.00   Corporate Sponsorship
 Western Pennsylvania
Parkinson Institute                $25,000.00   Corporate Sponsorship
Parkinson Society of                  $250.00   Corporate Sponsorship
 Greenville Area
Parkinson Support Group of          $2,000.00   Educational Grants
 Upstate NY
Parkinson Voice Project             $2,500.00   Corporate Sponsorship
Parkinsons Action Network           $1,000.00   Corporate Sponsorship
 Foundation
Parkinsons Action Network           $1,000.00   Corporate Sponsorship
 Foundation
Parkinsons Action Network           $2,500.00   Corporate Sponsorship
 Foundation
Parkinsons Action Network           $5,000.00   Corporate Sponsorship
 Foundation
Parkinsons And Movement             $2,000.00   Corporate Sponsorship
 Disorder Foundation
Parkinson's Disease                $50,000.00   Educational Grants
 Foundation
Parkinsons Disease Research         $1,000.00   Corporate Sponsorship
 Society
Parkinson's Resources of            $5,000.00   Patient Support
 Oregon
Parkinson's Resources of            $2,500.00   Corporate Sponsorship
 Oregon
Partnership for A Drug-Free        $50,000.00   Charitable Donation
 America
Patient Access Network          $3,000,000.00   Charitable Donation
 Foundation
Patient Access Network          $5,000,000.00   Charitable Donation
 Foundation
Patient Access Network          $5,000,000.00   Charitable Donation
 Foundation
Patient Access Network            $250,000.00   Charitable Donation
 Foundation
Patient Access Network            $387,500.00   Charitable Donation
 Foundation
Patient Access Network            $400,000.00   Charitable Donation
 Foundation
Patient Access Network            $500,000.00   Charitable Donation
 Foundation
Patient Empowerment Network         $9,000.00   Educational Grants
Patient Empowerment Network        $20,000.00   Patient Support
Patient Empowerment Network        $20,000.00   Educational Grants
Patient Empowerment Network        $35,000.00   Educational Grants
Pediatric Endocrinology             $5,000.00   Corporate Sponsorship
 Nursing Society
Pediatric Ibd Foundation           $15,000.00   Corporate Sponsorship
Pediatric Specialists of            $2,500.00   Corporate Sponsorship
 Virginia LLC
Pennsylvania Biotechnology          $3,000.00   Corporate Sponsorship
 Association
Pennsylvania Prostate               $5,000.00   Patient Support
 Cancer Coalition
Pennsylvania Society of            $15,000.00   Corporate Sponsorship
 Gastroenterology
Pennsylvania State Univ           $135,000.00   Educational Grants
Pennsylvania State Univ            $50,000.00   Educational Grants
Pennsylvania State Univ           ($3,067.00)   Educational Grants
Pennsylvania State Univ            $50,000.00   Educational Grants
Pennsylvania State Univ           ($9,660.00)   Educational Grants
Pennsylvania State Univ          ($32,062.00)   Educational Grants
Pennsylvania State Univ            $75,000.00   Educational Grants
Pennsylvania State Univ            $75,000.00   Educational Grants
Philadelphia Dermatological        $75,000.00   Corporate Sponsorship
 Society
Philadelphia Fight                  $5,000.00   Corporate Sponsorship
Philadelphia Fight                  $2,500.00   Corporate Sponsorship
Phmcy Quality Alliance             $10,000.00   Educational Grants
Phrmct Care Mgmt Asoc              $75,000.00   Corporate Sponsorship
Phrmct Care Mgmt Asoc              $60,000.00   Corporate Sponsorship
Phrmct Care Mgmt Asoc              $85,000.00   Corporate Sponsorship
Phrmct Care Mgmt Asoc              $70,000.00   Corporate Sponsorship
Physicians' Education              $40,000.00   Educational Grants
 Resource, LLC
Physicians' Education              $85,000.00   Educational Grants
 Resource, LLC
Pikes Peak Habitat for              $2,500.00   Charitable Donation
 Humanity
Premier Cares Foundation            $5,000.00   Corporate Sponsorship
Premier Cares Foundation            $5,000.00   Corporate Sponsorship
President and Fellows of            $3,000.00   Educational Grants
 Harvard College
President and Fellows of            $5,000.00   Educational Grants
 Harvard College
Prevent Cancer Foundation          $25,000.00   Corporate Sponsorship
Prevent Cancer Foundation          $10,000.00   Corporate Sponsorship
Prevent Cancer Foundation          $75,000.00   Corporate Sponsorship
Prime Education, Inc.             $198,011.00   Educational Grants
Prime Education, Inc.             $400,000.00   Educational Grants
Project Inform Inc.                $75,000.00   Patient Support
Project Inform Inc.                $75,000.00   Charitable Donation
Prostate Cancer Education           $2,500.00   Corporate Sponsorship
 Council
Prostate Cancer Foundation          $4,000.00   Corporate Sponsorship
 Chicago
Prostate Cancer Research           $25,000.00   Educational Grants
 Institute
Prostate Cancer Research           $10,000.00   Corporate Sponsorship
 Institute
Prostate Health Education          $15,000.00   Educational Grants
 Network, Inc.
Prostate Health Education          $15,000.00   Educational Grants
 Network, Inc.
Prostate Health                     $5,000.00   Corporate Sponsorship
 International
Prostate Health                     $5,000.00   Corporate Sponsorship
 International
Protein Society                     $1,500.00   Educational Grants
Puerto Rico Academy of              $5,000.00   Corporate Sponsorship
 Family Physician
Puerto Rico Community               $5,000.00   Educational Grants
 Network for Clinical
 Research On Aids Inc.
Puerto Rico                        $20,000.00   Educational Grants
 Gastroenterology
 Association
Puerto Rico                        $10,000.00   Educational Grants
 Gastroenterology
 Association
Purdue University                 $125,000.00   Educational Grants
Purdue University                 $200,000.00   Educational Grants
Purdue University                 $300,000.00   Educational Grants
PVI Peerview Institute for        $100,000.00   Educational Grants
 Medical Education
PVI Peerview Institute for          ($207.00)   Educational Grants
 Medical Education
Quinsigamond Community                $500.00   Charitable Donation
 College
Rectors And Visitors of The         $3,000.00   Educational Grants
 University of Virginia
Regents of The University          $40,000.00   Fellowships or
 of California                                   Scholarships
Regents of The University          $25,000.00   Educational Grants
 of California
Regents of The University           $5,000.00   Educational Grants
 of California
Regents of The University           $3,500.00   Educational Grants
 of California
Regents of The University           $5,000.00   Educational Grants
 of California
Regents of The University           $4,000.00   Educational Grants
 of California
Regents of The University          $10,000.00   Educational Grants
 of California
Regents of The University           $2,000.00   Educational Grants
 of Michigan
Regents of The University          $10,000.00   Educational Grants
 of Michigan
Regents of The University          $10,000.00   Corporate Sponsorship
 of Michigan
Regents University of              $40,000.00   Fellowships or
 California Los Angeles                          Scholarships
Regents University of              $10,000.00   Educational Grants
 California Los Angeles
Regents University of              $40,000.00   Fellowships or
 California Los Angeles                          Scholarships
Regents University of               $5,000.00   Educational Grants
 California Los Angeles
Respiratory Health                  $3,500.00   Corporate Sponsorship
 Association of
 Metropolitan Chicago
Respiratory Health                  $4,050.00   Corporate Sponsorship
 Association of
 Metropolitan Chicago
Rheumatism Society of The          $15,000.00   Corporate Sponsorship
 District of Columbia
Rheumatism Society of The           $5,000.00   Corporate Sponsorship
 District of Columbia
Rheumatology Alliance of           $25,000.00   Corporate Sponsorship
 Louisiana
Rheumatology Nurses Society        $29,700.00   Corporate Sponsorship
Rhode Island Pharmacy                 $600.00   Corporate Sponsorship
 Association
Riverside Medical Clinic            $7,500.00   Patient Support
 Charitable Foundation
Robert Michael Educational        $236,065.00   Educational Grants
 Institute LLC
Robert Michael Educational         $90,000.00   Educational Grants
 Institute LLC
Robert Michael Educational        $275,000.00   Educational Grants
 Institute LLC
Robert Michael Educational         $90,000.00   Educational Grants
 Institute LLC
Rock Hlth Inc.                     $15,000.00   Corporate Sponsorship
Rush University Medical            $15,000.00   Educational Grants
 Center
Rush University Medical             $5,000.00   Educational Grants
 Center
Rutgers University                  $1,250.00   Charitable Donation
 Foundation
Rutgers, The State                 $60,000.00   Educational Grants
 University of New Jersey
Rutgers, The State                 $25,000.00   Educational Grants
 University of New Jersey
Rutgers, The State                 $60,000.00   Educational Grants
 University of New Jersey
Rutgers, The State                 $25,000.00   Educational Grants
 University of New Jersey
Safety Pharmacology Society         $5,000.00   Educational Grants
Saint Francis Hospital And         $15,000.00   Educational Grants
 Medical Center
Saint Louis University             $50,000.00   Corporate Sponsorship
 Hospital
Scientists Center for               $2,500.00   Educational Grants
 Animal Welfare
Scott And White Healthcare            $300.00   Corporate Sponsorship
 Foundation
Scripps Health                     $75,000.00   Educational Grants
Scripps Research Institute          $2,000.00   Educational Grants
Scripps Research Institute          $2,000.00   Educational Grants
Sexual Medicine Society of         $25,000.00   Educational Grants
 North America
Sexual Medicine Society of        $225,000.00   Corporate Sponsorship
 North America
Shanti Project Inc.                $20,000.00   Patient Support
Smart Ride The                     $25,000.00
                                             Corporate
                                  Sponsorship
Sociedad Dermatologica De          $20,000.00   Corporate Sponsorship
 Puerto Rico
Sociedad Dermatologica De          $10,000.00   Corporate Sponsorship
 Puerto Rico
Sociedad Endocrinologia            $10,000.00   Corporate Sponsorship
 Metabolismo Y Diabetes Del
 Sur
Sociedad Puertorriquena De         $15,000.00   Corporate Sponsorship
 Endocronologia Y
 Diabetologia
Sociedad Puertorriquena De         $10,000.00   Corporate Sponsorship
 Endocronologia Y
 Diabetologia
Sociedad Puertorriquena De          $5,000.00   Corporate Sponsorship
 Pediatria
Sociedad Puertorriquena De          $5,000.00   Corporate Sponsorship
 Pediatria
Sociedad Puertorriquena De          $5,000.00   Corporate Sponsorship
 Pediatria
Society for Investigative          $20,000.00   Educational Grants
 Dermatology
Society for Leukocyte               $1,500.00   Educational Grants
 Biology
Society for Mucosal                $16,398.00   Corporate Sponsorship
 Immunology
Society for Neuroscience          ($2,500.00)   Educational Grants
Society for Neuroscience            $1,000.00   Educational Grants
Society for Neuroscience            $2,000.00   Educational Grants
Society for Translational          $15,000.00   Educational Grants
 Oncology
Society of Dermatology             $20,000.00   Corporate Sponsorship
 Physician Assistants
Society of Dermatology             $45,000.00   Corporate Sponsorship
 Physician Assistants
Society of Dermatology             $30,000.00   Corporate Sponsorship
 Physician Assistants
Society of Gastroenterology        $25,000.00   Educational Grants
 Nurses & Associates
Society of Neuro Oncology          $16,000.00   Corporate Sponsorship
Society of Nuclear Medicine         $4,000.00   Corporate Sponsorship
Society of Toxicologic             $15,000.00   Corporate Sponsorship
 Pathology
Socty of Toxicology                 $2,000.00   Fellowships or
                                                 Scholarships
Somos El Futuro, Inc.               $5,000.00   Corporate Sponsorship
South Carolina Alliance of          $5,000.00   Corporate Sponsorship
 Health Plans
Southern Illinois                   ($711.12)   Fellowships or
 University                                      Scholarships
Spondylitis Association of         $40,000.00   Educational Grants
 America
Spondylitis Association of         $19,000.00   Educational Grants
 America
Spondyloarthritis Research         $25,000.00   Corporate Sponsorship
 And Treatment Network
 Spartan
St. Christophers Foundation         $5,000.00   Corporate Sponsorship
 for Children
St. Lukes Regional Medical         $10,000.00   Corporate Sponsorship
 Center
St. Luke's-Roosevelt                $5,000.00   Educational Grants
 Hospital Center
Take A Breather Foundation         $10,000.00   Corporate Sponsorship
Tampa Bay Latin American            $3,000.00   Corporate Sponsorship
 Medical Society
Team Fox North Texas                  $500.00   Corporate Sponsorship
Tennessee Rheumatology              $7,500.00   Corporate Sponsorship
 Society
Teratology Society                  $2,000.00   Educational Grants
Test Positive Awareness            $30,000.00   Corporate Sponsorship
 Network
Texas Liver Inst The               $30,000.00   Corporate Sponsorship
Texas Osteopathic Medical           $1,000.00   Corporate Sponsorship
 Association
Texas Urological Society            $6,000.00   Corporate Sponsorship
Thomas Jefferson University       $500,000.00   Educational Grants
 Medical College
Thomas Jefferson University        $10,000.00   Educational Grants
 Medical College
Thomas Jefferson University         $2,500.00   Corporate Sponsorship
 Medical College
Torrington Area Parkinsons            $500.00   Corporate Sponsorship
 Support Group
Trustees of The University         $40,000.00   Educational Grants
 of Pennsylvania
Twine Clinical Consulting         $411,950.00   Educational Grants
 LLC
Ultimate Med Academy Med          ($3,550.00)   Educational Grants
 Learning Grp LLC
United States Adult Cystic          $7,500.00   Educational Grants
 Fibrosis Association
Univ Hlth Srvc At Stony            $20,000.00   Educational Grants
 Point Inc.
Univ of Colorado Denver             $2,500.00   Educational Grants
 School of Medicine
Universidad Central Del            $10,000.00   Educational Grants
 Caribe, Inc.
University At Buffalo               $1,250.00   Charitable Donation
 Foundation Inc.
University of Alabama At           $40,000.00   Fellowships or
 Birmingham                                      Scholarships
University of California--         $10,000.00   Educational Grants
 San Francisco
University of California           $30,000.00   Educational Grants
 Berkeley
University of California            $5,000.00   Educational Grants
 Irvine
University of Chicago            ($75,000.00)   Educational Grants
University of Chicago              $65,000.00   Educational Grants
University of Chicago               $5,000.00   Educational Grants
University of Chicago               $7,000.00   Educational Grants
University of Chicago             $157,000.00   Educational Grants
University of Chicago             ($4,249.00)   Educational Grants
University of Chicago             ($3,746.25)   Educational Grants
University of Chicago               $1,000.00   Corporate Sponsorship
University of Chicago             $400,000.00   Educational Grants
University of Chicago               $1,500.00   Educational Grants
University of Chicago            ($13,195.00)   Educational Grants
University of Cincinnati           $60,000.00   Educational Grants
University of Cincinnati         ($25,000.00)   Educational Grants
University of Cincinnati         ($50,000.00)   Educational Grants
University of Cincinnati         ($25,000.00)   Educational Grants
University of Cincinnati        $2,081,222.00   Educational Grants
University of Cincinnati            $5,000.00   Educational Grants
University of Cincinnati            $2,000.00   Educational Grants
University of Cincinnati           $30,000.00   Educational Grants
University of Cincinnati            $8,000.00   Educational Grants
University of Cincinnati           $75,000.00   Educational Grants
University of Connecticut          $40,000.00   Fellowships or
                                                 Scholarships
University of Connecticut          $12,000.00   Fellowships or
                                                 Scholarships
University of Florida             $125,875.00   Educational Grants
University of Florida             ($5,709.00)   Educational Grants
University of Florida               $1,500.00   Educational Grants
 Foundation Inc.
University of Florida              $40,000.00   Fellowships or
 Foundation Inc.                                 Scholarships
University of Illinois             $12,000.00   Corporate Sponsorship
University of Illinois             $12,000.00   Corporate Sponsorship
University of Louisville           $15,000.00   Educational Grants
 Research Foundation, Inc.
University of Maryland              $5,500.00   Educational Grants
University of Maryland             $10,000.00   Educational Grants
 Baltimore
University of Maryland              $1,250.00   Charitable Donation
 Baltimore Foundation
University of Massachusetts         $2,500.00   Charitable Donation
 Med School
University of Miami                $25,000.00   Educational Grants
University of Miami                $10,000.00   Educational Grants
University of Miami                $50,000.00   Corporate Sponsorship
 Department of Dermatology
University of Minnesota             $1,250.00   Charitable Donation
University of Minnesota             $1,250.00   Charitable Donation
University of Minnesota             $1,250.00   Charitable Donation
University of Missouri Dept           $500.00   Corporate Sponsorship
 of Neurology
University of Nebraska Med         $25,000.00   Educational Grants
 Ctr
University of Nebraska Med         $10,000.00   Educational Grants
 Ctr
University of Nebraska Med         $50,000.00   Educational Grants
 Ctr
University of Nebraska Med          $5,000.00   Educational Grants
 Ctr
University of North                $40,000.00   Fellowships or
 Carolina At Chapel Hill                         Scholarships
University of North                 $2,500.00   Educational Grants
 Carolina At Chapel Hill
University of Pittsburgh           $10,000.00   Educational Grants
University of Pittsburgh           $10,000.00   Educational Grants
University of Pittsburgh            $2,250.00   Educational Grants
University of Pittsburgh            $2,000.00   Educational Grants
University of Pittsburgh           $20,000.00   Educational Grants
University of Rochester,           $40,000.00   Fellowships or
 Center for Experiential                         Scholarships
 Learning
University of South Florida        $50,000.00   Educational Grants
 Hlth Professions
 Conferencing Corporation
University of South Florida        $10,000.00   Corporate Sponsorship
 Hlth Professions
 Conferencing Corporation
University of South Florida        $10,000.00   Corporate Sponsorship
 Hlth Professions
 Conferencing Corporation
University of Southern              $1,500.00   Educational Grants
 California
University of Southern           ($17,026.00)   Educational Grants
 California
University of Southern            ($2,974.00)   Educational Grants
 California
University of Southern             $71,800.00   Fellowships or
 California                                      Scholarships
University of Texas Hlth            $2,500.00   Educational Grants
 Scnc Ctr At San Antonio
University of Texas Hlth          $135,000.00   Corporate Sponsorship
 Scnc Ctr At San Antonio
University of Texas Hlth           $50,000.00   Educational Grants
 Scnc Ctr At San Antonio
University of Texas             ($100,000.00)   Educational Grants
 Southwestern Med Ctr
University of The                   $1,500.00   Corporate Sponsorship
 Philippines Med Alumni
 Socty In America Nevada
University of Toledo                $2,000.00   Educational Grants
University of Utah                 $40,000.00   Fellowships or
                                                 Scholarships
Urological Association of          $10,000.00   Corporate Sponsorship
 Physician Assistants
Urological Association of          $25,000.00   Corporate Sponsorship
 Physician Assistants
Urology Center of Colorado          $7,500.00   Corporate Sponsorship
 Foundation
US Pain Foundation, Inc.           $25,000.00   Corporate Sponsorship
US Pain Foundation, Inc.           $30,000.00   Corporate Sponsorship
US Pain Foundation, Inc.           $80,000.00   Corporate Sponsorship
Us Too International Inc.           $5,000.00   Corporate Sponsorship
Us Too International Inc.           $5,000.00   Corporate Sponsorship
Us Too International Inc.          $25,000.00   Corporate Sponsorship
USMD Health System                 $10,000.00   Corporate Sponsorship
Van Andel Research                  $5,000.00   Educational Grants
 Institute
Vanderbilt University Med          $25,000.00   Fellowships or
 Ctr                                             Scholarships
Vanderbilt University               $2,500.00   Educational Grants
 Medical Center
Vindico Medical Education         $146,000.00   Educational Grants
 LLC
Vindico Medical Education         $500,000.00   Educational Grants
 LLC
Vindico Medical Education          $35,000.00   Educational Grants
 LLC
Virginia Commonwealth Univ          $1,250.00   Charitable Donation
 School of Medicine
Virginia Commonwealth Univ          $1,000.00   Corporate Sponsorship
 School of Medicine
Wall Las Memorias                  $25,000.00   Corporate Sponsorship
Washington State Urology            $7,500.00   Corporate Sponsorship
 Society
Washington University               $5,000.00   Educational Grants
Washington University             ($1,248.95)   Fellowships or
                                                 Scholarships
WC Research Inc.                    $8,500.00   Corporate Sponsorship
Webmd Global LLC                  $430,600.00   Educational Grants
Webmd Global LLC                $1,165,500.00   Educational Grants
Well Project Inc.                  $20,000.00   Charitable Donation
Western States Phmcy               $10,000.00   Corporate Sponsorship
 Conference for Phmcy
 Residents Fellowships &
 Preceptors
Wheaton Franciscan                    $500.00   Corporate Sponsorship
 Healthcare Foundation
Wisconsin Academy of Phys           $4,000.00   Corporate Sponsorship
 Assistants
Wisconsin Collaborative for         $2,500.00   Corporate Sponsorship
 Healthcare Quality
Wisconsin Dairyland Chapter         $1,910.00   Corporate Sponsorship
 of HIMSS
Wisconsin Medical Society             $450.00   Corporate Sponsorship
Wisconsin Rheumatology              $5,000.00   Corporate Sponsorship
 Association
Wishes And Dreams for               $2,500.00   Corporate Sponsorship
 Cystic Fibrosis
Wj Weiser And Associates           $20,000.00   Corporate Sponsorship
Wj Weiser And Associates           $10,000.00   Corporate Sponsorship
World Parkinson Coalition          $15,000.00   Educational Grants
 Inc.
World Parkinson Coalition         $207,000.00   Corporate Sponsorship
 Inc.
Yale University                  ($10,000.00)   Educational Grants
Yale University                    $25,000.00   Educational Grants
Yale University                     $2,500.00   Educational Grants
Young Survival Coalition           $30,000.00   Corporate Sponsorship
Zebrafish Disease Models           $10,000.00   Educational Grants
 Society
Zero The End of Prostate           $10,000.00   Corporate Sponsorship
 Cancer
Zero The End of Prostate          $250,000.00   Corporate Sponsorship
 Cancer
Zero The End of Prostate           $15,000.00   Corporate Sponsorship
 Cancer
Zero The End of Prostate            $2,500.00   Corporate Sponsorship
 Cancer
------------------------------------------------------------------------


                      Grants Donations Report--2016
    (Parentheses represent refunds of previously disclosed payments)
                         Report as of 3/31/2017
------------------------------------------------------------------------
         Recipient             Payment Amount           Purpose
------------------------------------------------------------------------
50 Hoops                           $10,000.00   Educational Grants
A And R Educational Grp LLC         $4,000.00   Corporate Sponsorship
A Runners Love                      $5,000.00   Corporate Sponsorship
AAALAC International                $5,000.00   Educational Grants
Academy of Managed Care            $25,000.00   Corporate Sponsorship
 Phmcy
Academy of Managed Care            $25,000.00   Corporate Sponsorship
 Phmcy
Academy of Managed Care            $18,000.00   Corporate Sponsorship
 Phmcy
Academy of Managed Care            $40,000.00   Corporate Sponsorship
 Phmcy
Academy of Managed Care            $50,000.00   Corporate Sponsorship
 Phmcy
Advances in Cosmetic And           $75,000.00   Corporate Sponsorship
 Med Dermatology Inc.
Advances in Cosmetic And           $75,000.00   Corporate Sponsorship
 Med Dermatology Inc.
Advances in Cosmetic And          $100,000.00   Corporate Sponsorship
 Med Dermatology Inc.
Adventist Hlth System--            $15,000.00   Corporate Sponsorship
 Sunbelt Inc.
Adventist Hlth System--            $15,000.00   Corporate Sponsorship
 Sunbelt Inc.
Advocate Hlth And Hospitals         $2,000.00   Educational Grants
 Corporation
Advocate Hlth And Hospitals         $2,500.00   Educational Grants
 Corporation
Aesthetic Dermatology              $25,000.00   Corporate Sponsorship
 Symposia
AIDS Action Committee               $5,000.00   Corporate Sponsorship
Aids Drug Assistance                $5,000.00   Charitable Donations
 Programs Advocacy Asoc
AIDS Foundation of Chicago          $7,500.00   Corporate Sponsorship
AIDS Foundation of Chicago          $7,500.00   Corporate Sponsorship
AIDS Foundation of Chicago        ($7,500.00)   Corporate Sponsorship
AIDS Foundation of Chicago         $75,000.00   Charitable Donations
AIDS Institute                     $50,000.00   Corporate Sponsorship
AIDS Institute                     $50,000.00   Corporate Sponsorship
AIDS Institute                     $30,000.00   Corporate Sponsorship
AIDS Institute                     $75,000.00   Corporate Sponsorship
Alabama Asoc of Hlth Plans          $3,000.00   Corporate Sponsorship
Alabama Dermatology Socty          $35,000.00   Corporate Sponsorship
 The
Albany Med Colg                     $5,000.00   Educational Grants
Albany Med Colg                    $10,000.00   Corporate Sponsorship
Albert Einstein Colg of            $10,000.00   Educational Grants
 Medicine Div of
 Dermatology Attending Asoc
Albert Einstein College of         $20,000.00   Educational Grants
 Medicine of Yeshiva
 University
Albert Einstein College of         $10,000.00   Educational Grants
 Medicine of Yeshiva
 University
Albert Einstein College of          $5,000.00   Educational Grants
 Medicine of Yeshiva
 University
Albert Einstein College of          $5,000.00   Educational Grants
 Medicine of Yeshiva
 University
Albert Einstein Hlthcr              $5,750.00   Corporate Sponsorship
 Ntwrk
Alliance for Aging Research        $30,000.00   Corporate Sponsorship
Alliance for Aging Research        $25,000.00   Corporate Sponsorship
Alzheimers Asoc                    $15,000.00   Educational Grants
Alzheimers Asoc                     $2,500.00   Corporate Sponsorship
American Academy of                $40,000.00   Charitable Donations
 Dermatology
American Academy of                $20,000.00   Corporate Sponsorship
 Dermatology
American Academy of                $13,550.00   Charitable Donations
 Dermatology
American Academy of                $40,000.00   Educational Grants
 Dermatology
American Academy of              ($60,000.00)   Educational Grants
 Dermatology
American Academy of               $250,000.00   Corporate Sponsorship
 Dermatology
American Academy of                $50,000.00   Educational Grants
 Dermatology
American Academy of                $10,000.00   Charitable Donations
 Dermatology
American Academy of Family         $15,500.00   Educational Grants
 Phys
American Academy of                 $9,290.00   Educational Grants
 Neurology Institute
American Academy of                $80,000.00   Corporate Sponsorship
 Neurology Institute
American Academy of                $20,720.70   Corporate Sponsorship
 Neurology Institute
American Academy of                $24,700.00   Educational Grants
 Neurology Institute
American Academy of                $10,010.00   Corporate Sponsorship
 Neurology Institute
American Academy of                $50,000.00   Fellowships and
 Neurology Institute                             Scholarships
American Academy of                 $2,700.00   Corporate Sponsorship
 Neurology Institute
American Academy of                $22,616.70   Corporate Sponsorship
 Neurology Institute
American Academy of                 $6,500.00   Corporate Sponsorship
 Ophthalmology AAO
American Academy of                $15,000.00   Corporate Sponsorship
 Ophthalmology AAO
American Academy of Phys           $10,000.00   Educational Grants
 Assistants
American Assoc for Cancer          $50,000.00   Educational Grants
 Research
American Assoc for Cancer          $20,000.00   Fellowships and
 Research                                        Scholarships
American Assoc for Cancer          $10,000.00   Educational Grants
 Research
American Assoc for Cancer          $50,000.00   Educational Grants
 Research
American Assoc for Cancer          $10,000.00   Educational Grants
 Research
American Assoc for Cancer          $25,000.00   Charitable Donations
 Research
American Assoc for Cancer          $20,000.00   Educational Grants
 Research
American Assoc for Cancer          $10,000.00   Educational Grants
 Research
American Assoc for Cancer          $10,000.00   Educational Grants
 Research
American Assoc for Cancer          $15,000.00   Educational Grants
 Research
American Assoc for Cancer          $15,000.00   Educational Grants
 Research
American Assoc for Cancer          $15,000.00   Educational Grants
 Research
American Assoc for Cancer          $50,000.00   Educational Grants
 Research
American Assoc for Cancer          $15,000.00   Educational Grants
 Research
American Assoc for Cancer          $10,000.00   Educational Grants
 Research
American Assoc for Lab             $20,000.00   Charitable Donations
 Animal Scnc Fdtn
American Assoc for The             $85,000.00   Corporate Sponsorship
 Study of Liver Diseases
American Assoc of Clinical         $15,000.00   Educational Grants
 Endocrinologists New
 Jersey Chapter
American Assoc of Clinical         $25,000.00   Educational Grants
 Endocrinologists New
 Jersey Chapter
American Assoc of Clinical        $328,000.00    Corporate Sponsorship
 Endocrinologists New
 Jersey Chapter
American Assoc of Phys of          $10,000.00   Corporate Sponsorship
 Indian Origin Arkansas
American Asosc of Phys of           $5,000.00   Corporate Sponsorship
 Indian Origin Arkansas
American Association for          $500,000.00   Charitable Donations
 The Study of Liver
 Diseases (AASLD
 Foundation)
American Association of            $50,000.00   Corporate Sponsorship
 Pharmaceutical Scientists
American Brain Tumor Asoc           $7,500.00   Corporate Sponsorship
American Brain Tumor Asoc           $5,000.00   Corporate Sponsorship
American Brain Tumor Asoc           $5,000.00   Corporate Sponsorship
American Brain Tumor Asoc          $10,000.00   Educational Grants
American Brain Tumor Asoc           $7,000.00   Educational Grants
American Cancer Society             $5,000.00   Corporate Sponsorship
American Cancer Society             $2,500.00   Corporate Sponsorship
 Cancer Action Network
American Cancer Society            $25,000.00   Corporate Sponsorship
 Cancer Action Network
American Cancer Society             $2,500.00   Corporate Sponsorship
 Cancer Action Network
American Cancer Society             $2,500.00   Corporate Sponsorship
 Cancer Action Network
American Cancer Society             $2,500.00   Corporate Sponsorship
 Cancer Action Network
American Cancer Society             $5,000.00   Corporate Sponsorship
 Cancer Action Network
American Cancer Society             $3,500.00   Corporate Sponsorship
 Cancer Action Network
American Cancer Society             $1,000.00   Corporate Sponsorship
 Cancer Action Network
American Cancer Society             $7,000.00   Corporate Sponsorship
 Cancer Action Network
American Cancer Society             $5,000.00   Corporate Sponsorship
 Cancer Action Network
American Chem Socty                 $2,500.00   Educational Grants
American Chem Socty                 $2,500.00   Educational Grants
American Chem Socty                 $2,500.00   Educational Grants
American Chem Socty                 $1,000.00   Educational Grants
American Childhood Cancer           $2,500.00   Corporate Sponsorship
 Organization
American Colg of Gastro           $100,000.00   Corporate Sponsorship
American Colg of Gastro            $15,640.00   Corporate Sponsorship
American Colg of Gastro            $15,640.00   Corporate Sponsorship
American Colg of Gastro            $15,640.00   Corporate Sponsorship
American Colg of Gastro            $41,400.00   Corporate Sponsorship
American Colg of Gastro            $10,000.00   Educational Grants
American Colg of Gastro           $500,000.00   Corporate Sponsorship
American Colg of Gastro            $20,000.00   Corporate Sponsorship
American Colg of Lab Animal        $30,000.00   Charitable Donations
 Medicine
American Colg of                   $30,000.00   Corporate Sponsorship
 Obstetricians And
 Gynecologists
American Colg of                   $32,500.00   Corporate Sponsorship
 Obstetricians And
 Gynecologists
American Colg of                    $2,500.00   Corporate Sponsorship
 Obstetricians And
 Gynecologists District 1
American Colg of Rheumlgy       $2,000,000.00   Corporate Sponsorship
 Research And Education
 Fdtn
American Colg of Rheumlgy       $1,500,000.00   Corporate Sponsorship
 Research And Education
 Fdtn
American Colg of Toxicology         $1,000.00   Corporate Sponsorship
American College of                $50,000.00   Educational Grants
 Rheumatology
American College of                $75,000.00   Corporate Sponsorship
 Rheumatology
American College of                $95,000.00   Fellowships and
 Rheumatology                                    Scholarships
American College of                $50,000.00   Educational Grants
 Rheumatology
American College of                $35,000.00   Educational Grants
 Rheumatology
American College of                $25,000.00   Educational Grants
 Rheumatology
American Drug Utilization          $20,000.00   Corporate Sponsorship
 Review Society Adurs
American Drug Utilization           $6,666.67   Corporate Sponsorship
 Review Society Adurs
American Drug Utilization           $6,666.67   Corporate Sponsorship
 Review Society Adurs
American Drug Utilization           $6,666.66   Corporate Sponsorship
 Review Society Adurs
American Federation for Med         $2,000.00   Educational Grants
 Research
American Gastro Asoc Inst          $50,000.00   Educational Grants
American Gastro Asoc Inst         $250,000.00   Educational Grants
American Gastro Asoc Inst          $33,300.00   Corporate Sponsorship
American Kdny Fund                  $3,000.00   Corporate Sponsorship
American Legion National           $10,000.00   Corporate Sponsorship
American Legion National           $10,000.00   Corporate Sponsorship
 Headquarters
American Liver Fdtn                 $2,500.00   Corporate Sponsorship
American Liver Fdtn               $246,500.00   Corporate Sponsorship
American Liver Fdtn                $10,000.00   Corporate Sponsorship
American Liver Fdtn                 $2,500.00   Corporate Sponsorship
American Liver Fdtn                 $2,500.00   Corporate Sponsorship
American Liver Fdtn                 $5,000.00   Educational Grants
American Liver Foundation          $35,000.00   Corporate Sponsorship
American Med Asoc Fdtn             $20,000.00   Corporate Sponsorship
American Med Grp Asoc               $6,000.00   Corporate Sponsorship
American Military Partner           $5,000.00   Corporate Sponsorship
 Association
American Neuro Asoc                 $5,000.00   Educational Grants
American Neuro Asoc                $25,000.00   Educational Grants
American Osteopathic Colg          $15,000.00   Corporate Sponsorship
 of Dermatology
American Pancreatic Asoc           $75,000.00   Educational Grants
American Pancreatic Asoc           $15,000.00   Patient Support
American Pancreatic Asoc           $50,000.00   Corporate Sponsorship
American Parkinson Disease          $5,000.00   Corporate Sponsorship
 Association Arizona
 Chapter
American Parkinson Disease            $500.00   Corporate Sponsorship
 Association Arizona
 Chapter
American Parkinson Disease          $1,000.00   Corporate Sponsorship
 Association Arizona
 Chapter
American Parkinson Disease          $3,500.00   Corporate Sponsorship
 Association Arizona
 Chapter
American Parkinson Disease            $500.00   Corporate Sponsorship
 Association Arizona
 Chapter
American Parkinson Disease          $1,500.00   Corporate Sponsorship
 Association Arizona
 Chapter
American Parkinson Disease          $2,500.00   Corporate Sponsorship
 Association Arizona
 Chapter
American Parkinson Disease            $500.00   Corporate Sponsorship
 Association Arizona
 Chapter
American Parkinson Disease          $5,000.00   Corporate Sponsorship
 Association Arizona
 Chapter
American Parkinson Disease          $3,000.00   Corporate Sponsorship
 Association Arizona
 Chapter
American Parkinson Disease          $1,000.00   Corporate Sponsorship
 Association Arizona
 Chapter
American Parkinson Disease         $55,000.00   Corporate Sponsorship
 Association Arizona
 Chapter
American Pharmacists Asoc           $3,000.00   Corporate Sponsorship
American Pharmacists Asoc          $13,500.00   Corporate Sponsorship
American Red Cross of              $10,000.00   Charitable Donations
 Greater Chicago
American Red Cross of              $50,000.00   Charitable Donations
 Greater Chicago
American Society for                $1,500.00   Educational Grants
 Experimental
 Neurotherapeutics
American Socty for Matrix           $1,000.00   Educational Grants
 Biology
American Socty for Mens            $10,000.00   Corporate Sponsorship
 Hlth The
American Socty for                  $1,500.00   Educational Grants
 Pharmacology and
 Experimental Thrpt The
 Aspet
American Socty for                  $5,750.00   Corporate Sponsorship
 Reproductive Medicine
American Socty for                 $25,000.00   Educational Grants
 Reproductive Medicine
American Socty for                 $50,000.00   Corporate Sponsorship
 Reproductive Medicine
American Socty of                  $15,000.00   Corporate Sponsorship
 Anesthesiologists
American Socty of Clinical         $20,000.00   Educational Grants
 Oncology
American Socty of                  $52,500.00   Corporate Sponsorship
 Hematology
American Socty of                  $10,000.00   Educational Grants
 Hematology
American Socty of                  $40,000.00   Educational Grants
 Hematology
American Socty of                  $60,000.00   Corporate Sponsorship
 Hematology
American Socty of                  $10,000.00   Charitable Donations
 Hematology
American Socty of                  $50,000.00   Educational Grants
 Hematology
American Socty of Nphro            $40,000.00   Corporate Sponsorship
American Socty of Nphro             $8,700.00   Corporate Sponsorship
American Thyroid Asoc Inc.         $35,000.00   Educational Grants
American Thyroid Asoc Inc.         $10,000.00   Corporate Sponsorship
American Urological Asoc.          $50,000.00   Educational Grants
 Education and Research
 Inc.
American Urological Asoc.          $40,000.00   Corporate Sponsorship
 Education and Research
 Inc.
American Urological Asoc.          $25,000.00   Corporate Sponsorship
 Education and Research
 Inc.
American Urological Asoc.          $50,000.00   Charitable Donations
 Education and Research
 Inc.
American Urological Asoc.          $20,000.00   Educational Grants
 Education and Research
 Inc.
American Urological Asoc.          $75,000.00   Educational Grants
 Education and Research
 Inc.
American Urological Asoc.           $5,000.00   Corporate Sponsorship
 Fdtn
American Urological Asoc           $10,000.00   Charitable Donations
 Fdtn
American Urological Asoc            $6,000.00   Corporate Sponsorship
 Inc. North Ctrl Section
American Urological Asoc            $6,000.00   Corporate Sponsorship
 Inc. Southeast Section
American Urological Asoc           $10,000.00   Corporate Sponsorship
 Inc. Western Section
American Urological Asoc            $6,000.00   Corporate Sponsorship
 South Ctrl Section
Americans for Med Progress        $100,000.00   Charitable Donations
Americares Foundation, Inc.        $10,000.00   Charitable Donations
Americares Foundation, Inc.        $25,000.00   Charitable Donations
Angel Fdtn                          $5,000.00   Corporate Sponsorship
Annenberg Center for Health       $750,000.00   Educational Grants
 Sciences at Eisenhower
Annenberg Center for Health        $90,000.00   Educational Grants
 Sciences at Eisenhower
Annenberg Center for Health        $65,000.00   Educational Grants
 Sciences at Eisenhower
Annenberg Center for Health        $25,000.00   Educational Grants
 Sciences at Eisenhower
Annenberg Center for Health        $85,000.00   Educational Grants
 Sciences at Eisenhower
Annenberg Center for Health       $350,000.00   Educational Grants
 Sciences at Eisenhower
Annenberg Center for Health        $75,000.00   Educational Grants
 Sciences at Eisenhower
Annenberg Center for Health       $500,000.00   Educational Grants
 Sciences at Eisenhower
Annenberg Center for Health        $25,000.00   Educational Grants
 Sciences at Eisenhower
Annenberg Center for Health       $500,000.00   Educational Grants
 Sciences at Eisenhower
Annenberg Center for Health       $200,000.00   Educational Grants
 Sciences at Eisenhower
Annenberg Center for Health        $75,000.00   Educational Grants
 Sciences at Eisenhower
Arkansas State Rheumlgy            $10,000.00   Corporate Sponsorship
 Asoc
Arthritis Foundation                $1,000.00   Educational Grants
Arthritis Foundation               $35,000.00   Corporate Sponsorship
Arthritis Foundation               $35,000.00   Educational Grants
Arthritis Foundation               $22,500.00   Educational Grants
Arthritis Foundation               $30,000.00   Corporate Sponsorship
Arthritis Foundation               $20,000.00   Corporate Sponsorship
Arthritis Foundation               $30,000.00   Corporate Sponsorship
Arthritis Foundation               $10,000.00   Corporate Sponsorship
Arthritis Foundation               $15,000.00   Educational Grants
Arthritis Foundation                $1,500.00   Corporate Sponsorship
Arthritis Foundation               $25,000.00   Corporate Sponsorship
Arthritis Foundation                $2,500.00   Corporate Sponsorship
Arthritis Foundation                $5,000.00   Corporate Sponsorship
Arthritis Foundation               $10,000.00   Corporate Sponsorship
Arthritis Foundation               $25,000.00   Corporate Sponsorship
Arthritis Foundation                $2,500.00   Corporate Sponsorship
Arthritis Foundation               $20,000.00   Corporate Sponsorship
Arthritis Foundation               $40,000.00   Corporate Sponsorship
Arthritis Foundation               $30,000.00   Corporate Sponsorship
Arthritis Foundation               $35,000.00   Corporate Sponsorship
Arthritis Foundation               $25,000.00   Corporate Sponsorship
Arthritis Foundation              $300,000.00   Corporate Sponsorship
Arthritis Foundation              $259,000.00   Corporate Sponsorship
Arthritis Foundation              $250,000.00   Corporate Sponsorship
Arthritis Foundation              $300,000.00   Corporate Sponsorship
Arthritis Foundation              $175,000.00   Corporate Sponsorship
Arthritis Patient Srvc             $10,000.00   Charitable Donations
Arthritis Patient Srvc             $15,000.00   Educational Grants
Arthritis Patient Srvc             $40,000.00   Educational Grants
Asco Cancer Fdtn                  $100,000.00   Charitable Donations
Asco Cancer Fdtn                   $60,000.00   Fellowships and
                                                 Scholarships
Asco Cancer Fdtn                   $30,500.00   Corporate Sponsorship
Asco Cancer Fdtn                   $28,000.00   Educational Grants
Asco Cancer Fdtn                   $28,000.00   Educational Grants
ASCO Cancer Fdtn                   $28,000.00   Educational Grants
ASCO Cancer Fdtn                    $5,000.00   Educational Grants
ASCO Cancer Fdtn                   $25,000.00   Educational Grants
Asoc De Enfermeria                  $6,000.00   Corporate Sponsorship
 Oncologica Y Hematologica
 De Puerto Rico Inc.
Asoc De Reumatologos De            $30,000.00   Corporate Sponsorship
 Puerto Rico
Asoc Latina De Asistencia Y         $1,000.00   Educational Grants
 Prevencion Del Cancer De
 Mama
Asoc of Univ Tech Managers          $5,000.00   Corporate Sponsorship
Asociacion De Salud Publica         $5,000.00   Educational Grants
 De Puerto Rico
Aspen Cancer Conference             $7,500.00   Educational Grants
 Inc.
Association of Women in            $40,000.00   Corporate Sponsorship
 Rheumatology
Association of Women in            $40,000.00   Corporate Sponsorship
 Rheumatology
Atlanta Dermatological Asoc        $10,000.00   Corporate Sponsorship
Autoimmune Advocacy                 $2,500.00   Corporate Sponsorship
 Alliance
Baehr Challenge Ltd                 $2,500.00   Corporate Sponsorship
Balm In Gilead Inc.                $75,000.00   Corporate Sponsorship
Baylor Colg Medicine Inf          $100,000.00   Fellowships and
 Dis                                             Scholarships
Baylor Colg Medicine Inf            $3,500.00   Educational Grants
 Dis
Baylor Hlth Care System            $50,000.00   Fellowships and
 Fdtn                                            Scholarships
Baylor Scott And White             $20,000.00   Educational Grants
 Health
Baylor Univ Med Ctr                $25,000.00   Educational Grants
Baylor Univ Med Ctr                $25,000.00   Educational Grants
Baylor Univ Med Ctr                $20,000.00   Educational Grants
Beth Israel Deaconess Med          $40,000.00   Fellowships and
 Ctr                                             Scholarships
Beth Israel Deaconess Med          $30,000.00   Fellowships and
 Ctr                                             Scholarships
Beth Israel Deaconess Med          $27,000.00   Fellowships and
 Ctr                                             Scholarships
Beth Israel Deaconess Med           $7,500.00   Educational Grants
 Ctr
Beth Israel Deaconess Med           ($592.19)   Fellowships and
 Ctr                                             Scholarships
Bexar County Physician              $2,500.00   Corporate Sponsorship
 Assistant Society
Bioconnections LLC                 $30,000.00   Corporate Sponsorship
Black Hills Arthritis Asoc          $2,200.00   Educational Grants
Boomer Esiason Fdtn                $25,000.00   Corporate Sponsorship
Boomer Esiason Fdtn               $400,000.00   Corporate Sponsorship
Borland Groover Fdtn                  $500.00   Corporate Sponsorship
Boston Center for                   $5,000.00   Corporate Sponsorship
 Independent Living
Boston Socty Inc.                   $4,000.00   Corporate Sponsorship
Boston Socty Inc.                   $4,000.00   Corporate Sponsorship
Boston Univ Medcn Psychtry         $40,000.00   Fellowships and
                                                 Scholarships
Boston Univ Medcn Psychtry         $45,000.00   Educational Grants
Boston Univ Medcn Psychtry         $10,000.00   Educational Grants
Boston Univ Medcn Psychtry        $100,000.00   Educational Grants
Boston Univ Medcn Psychtry        ($2,482.00)   Educational Grants
Boston Univ Medcn Psychtry         $40,000.00   Fellowships and
                                                 Scholarships
Boston Univ Medcn Psychtry         $85,000.00   Educational Grants
Brian Grant Fdtn The               $25,000.00   Corporate Sponsorship
Brian Grant Fdtn The               $30,000.00   Educational Grants
Brian Grant Fdtn The               $10,000.00   Corporate Sponsorship
Brigham And Women's               $250,000.00   Educational Grants
 Hospital, Inc.
Brigham And Women's                $40,000.00   Fellowships and
 Hospital, Inc.                                  Scholarships
Bucks Montgomery Counties           $1,000.00   Corporate Sponsorship
 Oncology Nursing Socty
Business Hlth Coalition             $3,300.00   Corporate Sponsorship
 Fdtn
California Assn Physcn Grps        $20,000.00   Corporate Sponsorship
 Fnd
California Assn Physcn Grps        $10,000.00   Corporate Sponsorship
 Fnd
California Chronic Care            $35,000.00   Corporate Sponsorship
 Coalition
California Inst of Tech             $5,000.00   Fellowships and
                                                 Scholarships
California Issues forum            $15,000.00   Corporate Sponsorship
California Life Sciences            $3,000.00   Corporate Sponsorship
 Association
California Life Sciences            $5,000.00   Corporate Sponsorship
 Association
California Life Sciences            $1,500.00   Corporate Sponsorship
 Association
California Pacific Med Ctr          $2,000.00   Corporate Sponsorship
 Fdtn
California Rheumlgy                 $3,000.00   Corporate Sponsorship
 Alliance
California Socty of                $10,000.00   Corporate Sponsorship
 Dermatology and
 Dermatology Surgry
Cancer And Leukemia Grp B          $30,000.00   Educational Grants
 Fdtn
Cancer Awareness of Nevada          $1,000.00   Corporate Sponsorship
Cancer Care                        $10,000.00   Educational Grants
Cancer Care                        $25,000.00   Educational Grants
Cancer Care                        $50,000.00   Charitable Donations
Cancer Care                        $20,000.00   Educational Grants
Cancer Care                        $20,000.00   Educational Grants
Cancer Care                        $10,000.00   Educational Grants
Cancer Care                        $10,000.00   Educational Grants
Cancer Care                       $100,000.00   Corporate Sponsorship
Cancer Fdtn for New Mexico          $2,500.00   Corporate Sponsorship
Cancer Molecular Thrpt              $1,500.00   Educational Grants
Cancer Research Inst                $7,500.00   Educational Grants
Cancer Support Community           $50,000.00   Corporate Sponsorship
Cancer Wellness Center              $2,500.00   Corporate Sponsorship
Carden Jennings Publishing         $15,000.00   Corporate Sponsorship
Carden Jennings Publishing          $5,000.00   Corporate Sponsorship
Caribe Gyn                          $5,000.00   Corporate Sponsorship
Caring Ambassadors Program         $35,000.00   Corporate Sponsorship
Caring Ambassadors Program        $200,000.00   Charitable Donations
Caring Ambassadors Program          $2,500.00   Corporate Sponsorship
Cascade AIDS Project                $5,000.00   Corporate Sponsorship
CE Outcomes LLC                    $96,770.00   Educational Grants
Cedars--Sinai Med Ctr              $10,000.00   Educational Grants
Cedars--Sinai Med Ctr              $40,000.00   Fellowships and
                                                 Scholarships
Center for Healthcare               $5,000.00   Corporate Sponsorship
 Innovation
Central Brain Tumor                $20,000.00   Educational Grants
 Registry of The United
 States
Chesapeake Uro Asoc                 $5,500.00   Corporate Sponsorship
Chesapeake Uro Asoc                 $7,500.00   Corporate Sponsorship
Chicago Council On Scnc and        $20,000.00   Corporate Sponsorship
 Technologies
Chicago Council On Scnc and         $5,000.00   Corporate Sponsorship
 Technologies
Childrens Digestive Hlth           $85,000.00   Educational Grants
 and Nutrition Fdtn
Childrens Digestive Hlth           $40,000.00   Fellowships and
 and Nutrition Fdtn                              Scholarships
Childrens Hosp Corporation          $3,000.00   Corporate Sponsorship
Chimp Haven                        $25,000.00   Charitable Donations
Chris Elliott Fund                 $10,000.00   Charitable Donations
Chronic Liver Disease Fdtn         $75,000.00   Corporate Sponsorship
Chronic Liver Disease Fdtn        $500,000.00   Educational Grants
Chronic Liver Disease Fdtn         $25,000.00   Corporate Sponsorship
Chronic Liver Disease Fdtn       ($25,824.00)   Educational Grants
Chronic Lymphoytic Leukemia        $15,000.00   Educational Grants
 Society Inc.
Chronic Lymphoytic Leukemia        $75,000.00   Educational Grants
 Society Inc.
Chronic Lymphoytic Leukemia        $50,000.00   Charitable Donations
 Society Inc.
Chronic Lymphoytic Leukemia        $65,000.00   Educational Grants
 Society Inc.
Chronic Lymphoytic Leukemia        $10,000.00   Educational Grants
 Society Inc.
Cincinnati Childrens Hosp          $40,000.00   Fellowships and
 Medic                                           Scholarships
Cincinnati Childrens Hosp          $22,500.00   Corporate Sponsorship
 Medic
Cleveland Clnc                     $65,000.00   Educational Grants
Cleveland Clnc                     $57,000.00   Educational Grants
Cleveland Clnc                      $5,000.00   Educational Grants
Cleveland Clnc                     $50,000.00   Educational Grants--
Cleveland Clnc                      $5,000.00   Educational Grants
Cleveland Clnc                      $4,000.00   Educational Grants
Cleveland Clnc                      $5,000.00   Corporate Sponsorship
Cleveland Clnc                    ($6,743.76)   Educational Grants
Cleveland Clnc                      $7,500.00   Educational Grants
Cleveland Clnc                    ($6,093.50)   Educational Grants
Cleveland Clnc                      $5,000.00   Educational Grants
Cleveland Clnc                   ($13,210.68)   Educational Grants
Cleveland Clnc                      $5,000.00   Educational Grants
Cleveland Clnc Fdtn                $50,000.00   Fellowships and
                                                 Scholarships
Cleveland Clnc Fdtn                $40,000.00   Fellowships and
                                                 Scholarships
Clinical Care Optn LLC            $175,000.00   Educational Grants
Clinical Care Optn LLC             $85,000.00   Educational Grants
Clinical Care Optn LLC             $75,000.00   Educational Grants
Clinical Care Optn LLC             $25,000.00   Educational Grants
Clinical Care Optn LLC            $173,615.00   Educational Grants
Clinical Care Optn LLC             $95,000.00   Educational Grants
Clinical Care Optn LLC            $347,520.00   Educational Grants
Clinical Care Optn LLC            $126,385.00   Educational Grants
Clinical Care Optn LLC             $50,000.00   Educational Grants
Clinical Care Optn LLC             $25,000.00   Educational Grants
Clinical Care Optn LLC           ($75,000.00)   Educational Grants
Clinical Care Optn LLC             $75,000.00   Educational Grants
Coalicion Para El Control          $12,500.00   Corporate Sponsorship
 De Hepatitis En Puerto
 Rico
Coalition for Prevention of        $10,000.00   Corporate Sponsorship
 Colorectal Cancer In
 Puerto Rico
Coalition On Positive              $20,000.00   Corporate Sponsorship
 Health Empowerment
Coalition On Positive              $50,000.00   Charitable Donations
 Health Empowerment
Coalition On Positive              $10,000.00   Corporate Sponsorship
 Health Empowerment
Cockerell Educational              $15,000.00   Corporate Sponsorship
 Foundation
Cold Spring Harbor Lab              $5,000.00   Educational Grants
Cold Spring Harbor Lab              $1,500.00   Educational Grants
Colegio Medicos--Cirujanos         $10,000.00   Educational Grants
 Pr
Collegium Internationale           $10,000.00   Corporate Sponsorship
Colorado Dietetic Asoc              $1,500.00   Corporate Sponsorship
Colorado Gerontological             $5,000.00   Corporate Sponsorship
 Society
Colorado Retina Asoc               $15,000.00   Corporate Sponsorship
Columbia Univ Med Ctr              $15,000.00   Educational Grants
Commty Fdtn                         $5,000.00   Corporate Sponsorship
Commty Fdtn                         $5,000.00   Corporate Sponsorship
Commty Liver Alliance              $75,000.00   Educational Grants
Commty Liver Alliance               $5,000.00   Corporate Sponsorship
Community Access National           $2,500.00   Corporate Sponsorship
 Network
Community Health                   $10,000.00   Corporate Sponsorship
Community Initiatives              $75,000.00   Corporate Sponsorship
Community Initiatives              $25,000.00   Corporate Sponsorship
Community Initiatives              $30,000.00   Corporate Sponsorship
Community Liver Alliance            $9,000.00   Corporate Sponsorship
Community Liver Alliance           $25,000.00   Corporate Sponsorship
Community Liver Alliance           $19,400.00   Corporate Sponsorship
Complete Conference Mgmt           $80,000.00   Educational Grants
Connecticut Advanced Nurse          $5,000.00   Corporate Sponsorship
 Practitioner Socty
Connecticut Advocates for             $500.00   Corporate Sponsorship
 Parkinsons Inc.
Connecting To Cure Crohns          $20,000.00   Corporate Sponsorship
 And Colitis
Consortium of Multiple            $150,000.00   Educational Grants
 Sclerosis Centers
Consortium of Multiple             $40,000.00   Educational Grants
 Sclerosis Centers
Consortium of Multiple             $85,000.00   Educational Grants
 Sclerosis Centers
Consortium of Multiple             $60,000.00   Educational Grants
 Sclerosis Centers
Consortium of Multiple             $25,000.00   Educational Grants
 Sclerosis Centers
Consortium of Multiple            $150,000.00   Educational Grants
 Sclerosis Centers
Continuing Educational            ($2,537.67)   Educational Grants
 Alliance LLC
Continuing Educational            ($2,537.67)   Educational Grants
 Alliance LLC
Continuing Educational            $375,000.00   Educational Grants
 Alliance LLC
Continuing Educational            $200,000.00   Educational Grants
 Alliance LLC
Continuing Educational            $375,000.00   Educational Grants
 Alliance LLC
Continuing Educational            $375,000.00   Educational Grants
 Alliance LLC
Continuing Educational            ($1,250.00)   Educational Grants
 Alliance LLC
Continuing Educational             $75,000.00   Educational Grants
 Alliance LLC
Continuing Educational             $99,440.00   Educational Grants
 Alliance LLC
Cornell Univ Weill Med Colg         $1,500.00   Educational Grants
Cornell Univ Weill Med Colg        $15,000.00   Educational Grants
Cornell Univ Weill Med Colg         $3,000.00   Educational Grants
Cornerstone Hlth Inc.             $150,000.00   Educational Grants
Cornerstone Hlth Inc.             ($3,750.00)   Educational Grants
Cornerstone Hlth Inc.              $90,000.00   Educational Grants
Cornerstone Hlth Inc.              $40,000.00   Educational Grants
Cornerstone Hlth Inc.              $90,000.00   Educational Grants
Cornerstone Hlth Inc.              $75,000.00   Educational Grants
Creighton Univ                     $10,000.00   Educational Grants
Critical Path Inst                 $25,000.00   Corporate Sponsorship
Crohns And Colitis                $165,000.00   Corporate Sponsorship
 Foundation
Crohns And Colitis                $110,000.00   Educational Grants
 Foundation of America
Crohns And Colitis                $100,000.00   Educational Grants
 Foundation of America
Crohns And Colitis                $100,000.00   Educational Grants
 Foundation of America
Crohns And Colitis                $100,000.00   Educational Grants
 Foundation of America
Crohns and Colitis                $100,000.00   Educational Grants
 Foundation of America
Crohns and Colitis                 $31,000.00   Educational Grants
 Foundation of America
Crohns and Colitis                 $25,000.00   Charitable Donations
 Foundation of America
Crohns and Colitis                 $25,000.00   Charitable Donations
 Foundation of America
Crohns and Colitis                  $1,500.00   Corporate Sponsorship
 Foundation of America
Crohns and Colitis                    $800.00   Corporate Sponsorship
 Foundation of America
Crohns and Colitis                  $2,500.00   Corporate Sponsorship
 Foundation of America
Crohns and Colitis                 $10,000.00   Corporate Sponsorship
 Foundation of America
Crohns and Colitis                 $10,250.00   Corporate Sponsorship
 Foundation of America
Crohns and Colitis                 $50,000.00   Charitable Donations
 Foundation of America
Crohns and Colitis                  $5,000.00   Corporate Sponsorship
 Foundation of America
Crohns and Colitis                  $2,500.00   Corporate Sponsorship
 Foundation of America
Crohns and Colitis                  $1,500.00   Corporate Sponsorship
 Foundation of America
Crohns and Colitis                  $1,500.00   Corporate Sponsorship
 Foundation of America
Crohns and Colitis                 $47,000.00   Corporate Sponsorship
 Foundation of America
Crohns and Colitis                $114,000.00   Corporate Sponsorship
 Foundation of America
Crohns and Colitis                  $5,000.00   Corporate Sponsorship
 Foundation of America
Crohns and Colitis                  $2,500.00   Corporate Sponsorship
 Foundation of America
Crohns and Colitis                  $2,000.00   Corporate Sponsorship
 Foundation of America
Crohns and Colitis                  $2,500.00   Corporate Sponsorship
 Foundation of America
Crohns and Colitis                 $15,000.00   Corporate Sponsorship
 Foundation of America
Crohns and Colitis                 $10,000.00   Corporate Sponsorship
 Foundation of America
Crohns and Colitis                  $1,000.00   Corporate Sponsorship
 Foundation of America
Crohns and Colitis                 $15,000.00   Corporate Sponsorship
 Foundation of America
Crohns and Colitis                $250,000.00   Educational Grants
 Foundation of America
Crohns and Colitis                $100,000.00   Fellowships and
 Foundation of America                           Scholarships
Crohns and Colitis                $400,000.00   Corporate Sponsorship
 Foundation of America
Crohns and Colitis                 $80,000.00   Charitable Donations
 Foundation of America
Crohns and Colitis                 $40,000.00   Corporate Sponsorship
 Foundation of America
Crohns and Colitis                 $40,000.00   Educational Grants
 Foundation of America
Ctrl Florida Phmcy Council         $15,000.00   Educational Grants
 Inc.
Ctrl Savannah River Area            $1,000.00   Corporate Sponsorship
 Csra Parkinson Support Grp
Curatio Cme Inst                 ($33,640.17)   Educational Grants
Cure CF                             $1,500.00   Corporate Sponsorship
Curepsp Inc.                       $15,000.00   Educational Grants
Cystic Fibrosis Fdtn--              $1,000.00   Corporate Sponsorship
 Albany
Cystic Fibrosis Fdtn--                $750.00   Corporate Sponsorship
 Albany
Cystic Fibrosis Fdtn--              $7,500.00   Corporate Sponsorship
 Albany
Cystic Fibrosis Fdtn--              $1,750.00   Corporate Sponsorship
 Albany
Cystic Fibrosis Fdtn--              $1,500.00   Corporate Sponsorship
 Albany
Cystic Fibrosis Fdtn--              $1,000.00   Corporate Sponsorship
 Albany
Cystic Fibrosis Fdtn--              $2,500.00   Corporate Sponsorship
 Albany
Cystic Fibrosis Fdtn                $4,000.00   Corporate Sponsorship
 Maryland Chapter
Cystic Fibrosis Fdtn                $5,750.00   Corporate Sponsorship
 Maryland Chapter
Cystic Fibrosis Research            $5,000.00   Corporate Sponsorship
 Fund Emilys Entourage
Cystic Fibrosis Research           $18,000.00   Corporate Sponsorship
 Inc.
Cystic Fibrosis Research            $7,000.00   Corporate Sponsorship
 Inc.
Cystic Fibrosis Research           $10,000.00   Corporate Sponsorship
 Inc.
Cystic Fibrosis Research           $10,000.00   Corporate Sponsorship
 Inc.
Cystic Fibrosis Research            $5,000.00   Corporate Sponsorship
 Inc.
Cystic Fibrosis Research            $3,000.00   Corporate Sponsorship
 Inc.
Cystic Fibrosis Services              $500.00   Corporate Sponsorship
Cystic Fibrosis Services              $500.00   Corporate Sponsorship
Cystic Fibrosis Services            $3,500.00   Corporate Sponsorship
Cystic Fibrosis Services            $1,000.00   Corporate Sponsorship
Cystic Fibrosis Services            $2,500.00   Corporate Sponsorship
Cystic Fibrosis Services            $2,000.00   Corporate Sponsorship
Cystic Fibrosis Services            $1,000.00   Corporate Sponsorship
Cystic Fibrosis Services            $2,000.00   Corporate Sponsorship
Cystic Fibrosis Services            $1,500.00   Corporate Sponsorship
Cystic Fibrosis Services            $1,750.00   Corporate Sponsorship
Cystic Fibrosis Services            $3,250.00   Corporate Sponsorship
Cystic Fibrosis Services            $1,750.00   Corporate Sponsorship
Cystic Fibrosis Services            $1,500.00   Corporate Sponsorship
Cystic Fibrosis Services            $1,000.00   Corporate Sponsorship
Cystic Fibrosis Services            $5,000.00   Corporate Sponsorship
Cystic Fibrosis Services            $7,500.00   Corporate Sponsorship
Cystic Fibrosis Services            $7,500.00   Corporate Sponsorship
Cystic Fibrosis Services            $2,500.00   Corporate Sponsorship
Cystic Fibrosis Services            $2,000.00   Corporate Sponsorship
Cystic Fibrosis Services            $5,000.00   Corporate Sponsorship
Cystic Fibrosis Services            $1,750.00   Corporate Sponsorship
Cystic Fibrosis Services            $5,000.00   Corporate Sponsorship
Cystic Fibrosis Services           $35,000.00   Corporate Sponsorship
Cystic Fibrosis Services           $15,000.00   Corporate Sponsorship
Cystic Fibrosis Services            $5,000.00   Corporate Sponsorship
Cystic Fibrosis Services            $1,000.00   Corporate Sponsorship
Cystic Fibrosis Services            $2,500.00   Corporate Sponsorship
Cystic Fibrosis Services            $2,000.00   Corporate Sponsorship
Cystic Fibrosis Services            $1,000.00   Corporate Sponsorship
Cystic Fibrosis Services            $1,000.00   Corporate Sponsorship
Cystic Fibrosis Services            $3,000.00   Corporate Sponsorship
Cystic Fibrosis Services            $3,500.00   Corporate Sponsorship
Cystic Fibrosis Services            $1,000.00   Corporate Sponsorship
Cystic Fibrosis Services            $5,000.00   Corporate Sponsorship
Cystic Fibrosis Services            $3,000.00   Corporate Sponsorship
Cystic Fibrosis Services            $2,500.00   Corporate Sponsorship
Cystic Fibrosis Services            $5,000.00   Corporate Sponsorship
Cystic Fibrosis Services            $3,000.00   Corporate Sponsorship
Cystic Fibrosis Services            $1,000.00   Corporate Sponsorship
Cystic Fibrosis Services            $3,500.00   Corporate Sponsorship
Cystic Fibrosis Services            $2,500.00   Corporate Sponsorship
Cystic Fibrosis Services            $1,000.00   Corporate Sponsorship
Cystic Fibrosis Services            $2,000.00   Corporate Sponsorship
Cystic Fibrosis Services            $5,000.00   Corporate Sponsorship
Cystic Fibrosis Services            $1,000.00   Corporate Sponsorship
Cystic Fibrosis Services            $2,500.00   Corporate Sponsorship
Cystic Fibrosis Services            $1,500.00   Corporate Sponsorship
Cystic Fibrosis Services           $10,000.00   Corporate Sponsorship
Cystic Fibrosis Services            $6,500.00   Corporate Sponsorship
Cystic Fibrosis Services            $5,000.00   Corporate Sponsorship
Cystic Fibrosis Services            $3,000.00   Corporate Sponsorship
Cystic Fibrosis Services            $1,750.00   Corporate Sponsorship
Cystic Fibrosis Services            $1,000.00   Corporate Sponsorship
Cystic Fibrosis Services           $35,000.00   Corporate Sponsorship
Cystic Fibrosis Services          $750,000.00   Corporate Sponsorship
Cystic Fibrosis Services            $5,000.00   Corporate Sponsorship
Cystic Fibrosis Services            $7,500.00   Corporate Sponsorship
Cystic Fibrosis Services            $7,500.00   Corporate Sponsorship
Cystic Fibrosis Services            $7,500.00   Corporate Sponsorship
Cystic Fibrosis Services            $6,500.00   Corporate Sponsorship
Cystic Fibrosis Services            $5,000.00   Corporate Sponsorship
Cystic Fibrosis Services            $5,000.00   Corporate Sponsorship
Cystic Fibrosis Services            $2,500.00   Corporate Sponsorship
Cystic Fibrosis Services            $1,000.00   Corporate Sponsorship
Cystic Fibrosis Services           $10,000.00   Corporate Sponsorship
Cystic Fibrosis Services            $1,500.00   Corporate Sponsorship
Dallas fort Worth Business          $5,000.00   Corporate Sponsorship
 Grp On Hlth
Danville D Elegance Fdtn            $2,500.00   Corporate Sponsorship
Dava Oncology Lp                   $50,000.00   Corporate Sponsorship
Dava Oncology Lp                  $150,000.00   Corporate Sponsorship
David A Winston Health              $5,500.00   Corporate Sponsorship
 Policy
Davis Phinney Fdtn                 $30,000.00   Educational Grants
Davis Phinney Fdtn                 $30,000.00   Educational Grants
Davis Phinney Fdtn                 $20,000.00   Corporate Sponsorship
Davis Phinney Fdtn                 $30,000.00   Educational Grants
Davis Phinney Fdtn                 $60,000.00   Educational Grants
Davis Phinney Fdtn                 $30,000.00   Educational Grants
Davis Phinney Fdtn                 $40,000.00   Corporate Sponsorship
Dermatology Education Fdtn         $30,000.00   Corporate Sponsorship
Dermatology Fdtn                  $135,000.00   Charitable Donations
Dermatology Fdtn                   $50,000.00   Corporate Sponsorship
Dermatology Nurses Asoc            $10,000.00   Educational Grants
Dermatology Nurses Asoc            $25,850.00   Corporate Sponsorship
Digestive Disease Week             $55,000.00   Corporate Sponsorship
Digestive Disease Week             $55,000.00   Corporate Sponsorship
Digestive Health Foundation        $25,000.00   Corporate Sponsorship
Digestive Health Physicians       $100,000.00   Corporate Sponsorship
 Association
Direct Relief                      $50,000.00   Charitable Donations
East Hawaii IPA                     $8,500.00   Corporate Sponsorship
Elsevier Inc.                      $40,000.00   Educational Grants
Employers Hlth Colition             $4,000.00   Corporate Sponsorship
 Inc.
Endocrine Education Inc.           $25,000.00   Educational Grants
Endocrine Education Inc.           $25,000.00   Educational Grants
Engineering Conferences             $1,500.00   Educational Grants
 International
Enviormental Mutagen Socty          $2,500.00   Corporate Sponsorship
Enzyme Mechanism Conference         $1,500.00   Educational Grants
Epilepsy Association of             $5,000.00   Corporate Sponsorship
 Central Florida
Epilepsy Fnd of North-             $20,000.00   Corporate Sponsorship
 Central Illinois Iowa and
 Nebraska
Epilepsy Foundation of              $5,000.00   Corporate Sponsorship
 Flordia Inc.
Epilepsy Foundation of             $18,000.00   Corporate Sponsorship
 Michigan
Epilepsy Foundation of             $20,000.00   Corporate Sponsorship
 Michigan
Epilepsy Foundation of New         $17,000.00   Corporate Sponsorship
 Jersey
Escuela De Medicina De             $20,000.00   Educational Grants
 Ponce
Escuela De Medicina De             $10,000.00   Educational Grants
 Ponce
Event 360 Inc.                      $8,330.00   Corporate Sponsorship
Excel Continuing Education          $5,000.00   Educational Grants
Excellence in Gastro              $100,000.00   Corporate Sponsorship
 Education LLC
Excellence in Rheumlgy            $100,000.00   Corporate Sponsorship
 Education LLC
Family Med Ctr Bolingbrook         $13,000.00   Corporate Sponsorship
Family Med Ctr Bolingbrook          $5,500.00   Corporate Sponsorship
Fdtn for Biomedical                $25,000.00   Charitable Donations
 Research
Federation of American              $1,500.00   Educational Grants
 Socty
Federation of American              $1,500.00   Educational Grants
 Socty
Federation of American              $1,500.00   Educational Grants
 Socty
Federation of American              $1,500.00   Educational Grants
 Socty
Federation of American              $1,500.00   Educational Grants
 Socty
Federation of American              $1,500.00   Educational Grants
 Socty
Federation of Clinical             $20,000.00   Educational Grants
 Immunology Socty
Federation of Clinical             $25,000.00   Educational Grants
 Immunology Socty
Federation of Clinical             $12,500.00   Educational Grants
 Immunology Socty
Florida Hlth Care Coalition         $5,000.00   Corporate Sponsorship
Florida Socty of                   $20,000.00   Corporate Sponsorship
 Dermatology Phys
 Assistants Inc.
Florida Socty of Rheumlgy          $25,000.00   Corporate Sponsorship
Focus Med Communications          $100,000.00   Corporate Sponsorship
Force--Facing Our Risk of          $10,000.00   Corporate Sponsorship
 Cancer Emp
Force--Facing Our Risk of          $10,000.00   Charitable Donations
 Cancer Emp
Foster Ocular Immunology           $40,000.00   Corporate Sponsorship
 Socty
Foundation for Veterans            $20,000.00   Corporate Sponsorship
 Health Care
Foundation of Consortium of        $12,280.00   Fellowships and
 Multiple Sclerosis Centers                      Scholarships
 CMSC
Foundation of Consortium of        $25,000.00   Educational Grants
 Multiple Sclerosis Centers
 CMSC
Foundation of Consortium of        $10,000.00   Charitable Donations
 Multiple Sclerosis Centers
 CMSC
Friends of Cancer Research         $50,000.00   Corporate Sponsorship
Friends of Parkinsons               $1,000.00   Corporate Sponsorship
Friends of The St Louis            $50,000.00   Corporate Sponsorship
 Univ Liver Ctr
Fund for Public Hlth In New       $200,000.00   Educational Grants
 York
Fundacion Alfredo Ruiz              $5,000.00   Corporate Sponsorship
Fundacion Daledale Inc.             $3,000.00   Corporate Sponsorship
Fundacion De Esclerosis             $3,000.00   Corporate Sponsorship
 Multiple De Puerto Rico
Fundacion Puertorriquena De         $5,000.00   Corporate Sponsorship
 Enfermedades Reumaticas
Galien Foundation                  $22,500.00   Corporate Sponsorship
Galien Foundation                  $30,000.00   Corporate Sponsorship
Gastro--Intestinal Research        $25,000.00   Corporate Sponsorship
 Fdtn
Gastro--Intestinal Research        $50,000.00   Corporate Sponsorship
 Fdtn
Gastrointestinal And Liver         $75,000.00   Educational Grants
 Association of The
 Americas Inc.
Gateway for Cancer Research        $10,000.00   Charitable Donations
Georgetown Univ Hosp Phmcy         $50,000.00   Fellowships and
                                                 Scholarships
Georgia Dermatology Phys           $20,000.00   Corporate Sponsorship
 Assistants
Georgia Doty Hiv &                 $10,000.00   Educational Grants
 Hepatitis Commty Outreach
 Inc.
Georgia Prostate Cancer             $2,500.00   Educational Grants
 Coalition The
Georgia Society of Clinical        $25,000.00   Corporate Sponsorship
 Oncology
Georgia Socty of                    $8,000.00   Corporate Sponsorship
 Rhematology
Global Academy for Medical         $18,000.00   Corporate Sponsorship
 Education
Global Academy for Medical         $76,500.00   Corporate Sponsorship
 Education
Global Academy for Medical         $36,000.00   Corporate Sponsorship
 Education
Global Academy for Medical         $54,000.00   Corporate Sponsorship
 Education
Global Academy for Medical         $90,000.00   Corporate Sponsorship
 Education
Global Alliance for Medical        $10,000.00   Educational Grants
 Education
Global Alliance for Patient        $30,000.00   Corporate Sponsorship
 Access
Global Biological Standards         $2,000.00   Educational Grants
 Inst
Globalization of                   $10,000.00   Corporate Sponsorship
 Pharmaceutics Education
 Ntwrk
Good Grief                            $500.00   Corporate Sponsorship
Gordon Research Conferences         $1,500.00   Educational Grants
Gordon Research Conferences         $1,500.00   Educational Grants
Gordon Research Conferences        $10,000.00   Corporate Sponsorship
Gordon Research Conferences         $1,500.00   Educational Grants
Gordon Research Conferences         $1,500.00   Educational Grants
Gordon Research Conferences         $1,500.00   Educational Grants
Gordon Research Conferences         $1,500.00   Educational Grants
Gordon Research Conferences         $1,500.00   Educational Grants
Gordon Research Conferences         $1,500.00   Educational Grants
Gordon Research Conferences         $1,500.00   Educational Grants
Gordon Research Conferences         $1,500.00   Educational Grants
Gordon Research Conferences         $1,500.00   Educational Grants
Gordon Research Conferences         $1,500.00   Educational Grants
Gordon Research Conferences         $1,500.00   Educational Grants
Gordon Research Conferences         $1,500.00   Educational Grants
Gordon Research Conferences         $2,000.00   Educational Grants
Gordon Research Conferences         $1,500.00   Educational Grants
Gordon Research Conferences         $2,000.00   Educational Grants
Gordon Research Conferences         $2,000.00   Educational Grants
Gordon Research Conferences         $2,000.00   Educational Grants
Gordon Research Conferences         $2,000.00   Educational Grants
Great Lakes Chapter of The          $1,000.00   Corporate Sponsorship
 American Society for
 Pharmacology And
 Experimental Therapeutics
Gynecologic Oncology Grp           $35,000.00   Educational Grants
 The
Gynecologic Oncology Grp           $40,000.00   Educational Grants
 The
Gynecologic Oncology Grp           $40,000.00   Educational Grants
 The
Haymarket Med Education           ($2,553.09)   Educational Grants
Head for The Cure Fdtn              $7,500.00   Corporate Sponsorship
Healthcare Business Women's         $7,500.00   Corporate Sponsorship
 Association, Inc.
Healthcare Business Women's         $7,500.00   Corporate Sponsorship
 Association, Inc.
Healthwell Fdtn                   $507,000.00   Charitable Donations
Healthy Women                      $30,000.00   Corporate Sponsorship
Heart to Heart                     $10,000.00   Charitable Donations
 International Inc.
Heart to Heart                     $50,000.00   Charitable Donations
 International Inc.
Heb Grocery Company LP              $7,000.00   Corporate Sponsorship
Henry ford Hlth System              $2,000.00   Corporate Sponsorship
Henry M Jackson Fdtn                $5,559.67   Corporate Sponsorship
Henry M Jackson Fdtn                $5,559.67   Corporate Sponsorship
Henry M Jackson Fdtn                $5,559.66   Corporate Sponsorship
Henry M Jackson Fdtn               $10,000.00   Educational Grants
Hep C Connection                    $5,000.00   Corporate Sponsorship
Hep C Connection                   $25,000.00   Charitable Donations
Hep C Connection                    $5,000.00   Corporate Sponsorship
Hepatitis C Asoc                   $25,000.00   Educational Grants
Hepatitis Education Project        $75,000.00   Charitable Donations
Hepatitis Education Project        $24,000.00   Corporate Sponsorship
Hepatitis Education Project        $25,000.00   Corporate Sponsorship
Hepatitis Foundation              $250,000.00   Corporate Sponsorship
 International
Hepatitis Foundation                $5,000.00   Corporate Sponsorship
 International
Herbert Kosten Pancreatic           $2,000.00   Corporate Sponsorship
 Cancer Charitable Fund
Hidradenitis Suppurativa           $13,550.00   Charitable Donations
 Fdtn
Hitchcock Fdtn                      $8,000.00   Educational Grants
Hitchcock Fdtn                     $20,000.00   Educational Grants
HIV Treaters Med Asoc of           $10,000.00   Educational Grants
 Puerto Rico
Hlthcr Financial Mgmt Hfma         $50,000.00   Corporate Sponsorship
Hmp Communications                 $31,000.00   Corporate Sponsorship
Hmp Communications                 $50,000.00   Corporate Sponsorship
Hope Fdtn The                      $25,000.00   Educational Grants
Hope Healthcare Services              $600.00   Corporate Sponsorship
Houston Area Parkinson              $1,000.00   Corporate Sponsorship
 Society
Houston Business Coalition          $6,000.00   Corporate Sponsorship
 On Health
Howard Hanna Children's            $10,000.00   Charitable Donations
 Free Care Fund
Hubbard Street Dance               $10,000.00   Educational Grants
 Chicago
Human Growth Fdtn                   $5,000.00   Corporate Sponsorship
Human Growth Fdtn                  $10,000.00   Charitable Donations
Human Growth Fdtn                   $4,000.00   Corporate Sponsorship
Humboldt--Del Norte County          $1,100.00   Educational Grants
 Med Socty
Humboldt--Del Norte County          $4,000.00   Educational Grants
 Med Socty
Ibd Remedy Inc.                    $10,000.00   Charitable Donations
Illinois African American          $15,000.00   Corporate Sponsorship
 Coalition
Illinois Socty of                  $25,000.00   Corporate Sponsorship
 Dermatology Phys
 Assistants
Illinois Socty of                  $15,000.00   Corporate Sponsorship
 Dermatology Phys
 Assistants
Imedex LLC                         $50,000.00   Educational Grants
Imedex LLC                         $75,000.00   Educational Grants
Imedex LLC                         $75,000.00   Educational Grants
Imedex LLC                          $9,000.00   Educational Grants
Imedex LLC                         $25,000.00   Educational Grants
Imedex LLC                         $50,000.00   Educational Grants
Imedex LLC                          ($838.00)   Educational Grants
Imedex LLC                         $50,000.00   Educational Grants
Imedex LLC                         $75,000.00   Educational Grants
Improve Care Now Inc.              $15,000.00   Corporate Sponsorship
Indian Medical Association            $500.00   Corporate Sponsorship
 of New England
Indiana Parkinson Fdtn              $1,000.00   Corporate Sponsorship
Indiana Univ                        ($619.24)   Fellowships and
                                                 Scholarships
Indiana Univ Fdtn                  $50,000.00   Charitable Donations
Inflammatory Bowel Disease         $75,000.00   Educational Grants
 Support Fdtn
Inflammatory Bowel Disease        $200,000.00   Educational Grants
 Support Fdtn
Inflammatory Bowel Disease         $75,000.00   Educational Grants
 Support Fdtn
Innovation Development Inst       $250,000.00   Corporate Sponsorship
 Inc.
Integrated Benefits Inst           $25,000.00   Corporate Sponsorship
 Inc.
Integrated Med Fdtn                $15,000.00   Charitable Donations
Interfaith House                    $2,000.00   Charitable Donations
Intermountain Dermatology          $15,000.00   Educational Grants
 Socty
International Aids Socty--         $75,000.00   Educational Grants
 USA
International Aids Socty--         $75,000.00   Educational Grants
 USA
International Biometric             $4,925.00   Corporate Sponsorship
 Socty Eastern North
 American Region
International Chinese               $3,000.00   Corporate Sponsorship
 Statistical Asoc
International Dermatology         $250,000.00   Educational Grants
 Outcome Measures
International League of            $20,000.00   Charitable Donations
 Asoc for Rheumlgy
International Medical Corps        $50,000.00   Charitable Donations
International Organization        $145,000.00   Educational Grants
 of Multiple Sclerosis
 Nurses
International Organization         $60,000.00   Educational Grants
 of Multiple Sclerosis
 Nurses
International Parkinson And       $300,000.00   Corporate Sponsorship
 Movemen
International Socty for             $5,000.00   Educational Grants
 Antiviral Research
International Socty for The         $3,000.00   Educational Grants
 Study of Xenobiotics
International Socty for The         $2,500.00   Educational Grants
 Study of Xenobiotics
International Socty of             $40,000.00   Corporate Sponsorship
 Nphro
International Socty of              $1,500.00   Educational Grants
 Psychiatric Genetics
Iraq and Afghanistan               $15,000.00   Corporate Sponsorship
 Veterans
ISMPP--International Socty         $10,000.00   Corporate Sponsorship
 for Med
ISMPP--International Socty         $10,000.00   Corporate Sponsorship
 for Med
Jefferson Med Colg At               $3,000.00   Corporate Sponsorship
 Thomas Jefferson Univ
Jefferson Med Colg At               $3,000.00   Corporate Sponsorship
 Thomas Jefferson Univ
Jefferson Med Colg At               $7,500.00   Educational Grants
 Thomas Jefferson Univ
John P Mcgovern Museum of          $10,000.00   Corporate Sponsorship
 Health And Medical Science
Johns Hopkins Univ School          $50,000.00   Educational Grants
 of Medicine
Johns Hopkins Univ School          $20,000.00   Educational Grants
 of Medicine
Johns Hopkins Univ School           $1,500.00   Corporate Sponsorship
 of Medicine
Johns Hopkins Univ School          $40,000.00   Fellowships and
 of Medicine                                     Scholarships
Johns Hopkins Univ School          $99,750.00   Educational Grants
 of Medicine
Johns Hopkins Univ School          $35,000.00   Educational Grants
 of Medicine
Johns Hopkins Univ School           $7,000.00   Fellowships and
 of Medicine                                     Scholarships
Johns Hopkins Univ School          $90,000.00   Educational Grants
 of Medicine
Johns Hopkins Univ School          $50,000.00   Educational Grants
 of Medicine
JWC Covenant Inc.                  $25,000.00   Educational Grants
Kansas Univ Neuro Fdtn             $65,000.00   Educational Grants
Kelsey Research Fdtn               $35,000.00   Fellowships and
                                                 Scholarships
Kentuckiana Health                  $2,500.00   Corporate Sponsorship
 Collaborative
Kentucky Life Sciences              $5,000.00   Corporate Sponsorship
 Foundation
Keystone Symposia                  $25,000.00   Corporate Sponsorship
Laboratorio Clinico Toledo          $2,955.00   Patient Support
Laboratorio Clinico Toledo            $810.00   Patient Support
Laboratorio Clinico Toledo            $720.00   Patient Support
Laboratorio Clinico Toledo            $675.00   Patient Support
Laboratorio Clinico Toledo            $675.00   Patient Support
Laboratorio Clinico Toledo            $630.00   Patient Support
Laboratorio Clinico Toledo          $1,440.00   Patient Support
Laboratorio Clinico Toledo          $1,485.00   Patient Support
Laboratorio Clinico Toledo          $5,250.00   Patient Support
Laboratorio Clinico Toledo            $735.00   Patient Support
Laboratorio Clinico Toledo            $810.00   Patient Support
Laboratorio Clinico Toledo            $660.00   Patient Support
Laboratorio Clinico Toledo          $1,875.00   Patient Support
Laboratorio Clinico Toledo            $825.00   Patient Support
Laboratorio Clinico Toledo            $765.00   Patient Support
Laboratorio Clinico Toledo            $750.00   Patient Support
Laboratorio Clinico Toledo          $1,500.00   Patient Support
Laboratorio Clinico Toledo            $885.00   Patient Support
Laboratorio Clinico Toledo          $1,740.00   Patient Support
Laboratorio Clinico Toledo          $1,500.00   Patient Support
Laboratorio Clinico Toledo            $810.00   Patient Support
Laboratorio Clinico Toledo          $1,500.00   Patient Support
Laboratorio Clinico Toledo          $1,500.00   Patient Support
Laboratorio Clinico Toledo            $372.00   Patient Support
Laboratorio Clinico Toledo          $2,550.00   Patient Support
Laboratorio Clinico Toledo          $1,470.00   Patient Support
Laboratorio Clinico Toledo          $1,350.00   Patient Support
Laboratorio Clinico Toledo          $1,215.00   Patient Support
Laboratorio Clinico Toledo          $1,080.00   Patient Support
Laboratorio Clinico Toledo            $705.00   Patient Support
Laboratorio Clinico Toledo            $645.00   Patient Support
Laboratorio Clinico Toledo            $204.00   Patient Support
Laboratorio Clinico Toledo          $1,500.00   Patient Support
Laboratorio Clinico Toledo            $765.00   Patient Support
Laboratorio Clinico Toledo          $1,905.00   Patient Support
Laboratorio Clinico Toledo          $1,500.00   Patient Support
Laboratorio Clinico Toledo            $675.00   Patient Support
Laboratorio Clinico Toledo            $585.00   Patient Support
Laboratorio Clinico Toledo            $885.00   Patient Support
Laboratorio Clinico Toledo            $870.00   Patient Support
Laboratorio Clinico Toledo          $1,500.00   Patient Support
Laboratorio Clinico Toledo          $1,500.00   Patient Support
Laboratorio Clinico Toledo            $975.00   Patient Support
Laboratorio Clinico Toledo          $1,080.00   Patient Support
Laboratorio Clinico Toledo          $1,035.00   Patient Support
Laboratorio Clinico Toledo            $300.00   Patient Support
Laboratorio Clinico Toledo            $870.00   Patient Support
Laboratorio Clinico Toledo          $1,500.00   Patient Support
Laboratorio Clinico Toledo          $1,305.00   Patient Support
Laboratorio Clinico Toledo          $1,200.00   Patient Support
Laboratorio Clinico Toledo            $645.00   Patient Support
Laboratorio Clinico Toledo          $1,500.00   Patient Support
Laboratorio Clinico Toledo          $1,500.00   Patient Support
Laboratorio Clinico Toledo          $1,290.00   Patient Support
Laboratorio Clinico Toledo          $1,005.00   Patient Support
Laboratorio Clinico Toledo            $204.00   Patient Support
Laboratorio Clinico Toledo          $1,500.00   Patient Support
Laboratorio Clinico Toledo          $1,140.00   Patient Support
Laboratorio Clinico Toledo          $1,125.00   Patient Support
Laboratorio Clinico Toledo            $810.00   Patient Support
Laboratorio Clinico Toledo            $240.00   Patient Support
Laboratorio Clinico Toledo          $1,395.00   Patient Support
Laboratorio Clinico Toledo          $1,275.00   Patient Support
Laboratorio Clinico Toledo            $705.00   Patient Support
Laboratorio Clinico Toledo          $1,425.00   Patient Support
Laboratorio Clinico Toledo          $1,200.00   Patient Support
Laboratorio Clinico Toledo            $675.00   Patient Support
Laboratorio Clinico Toledo            $405.00   Patient Support
Laboratorio Clinico Toledo          $1,095.00   Patient Support
Laboratorio Clinico Toledo            $720.00   Patient Support
Laboratorio Clinico Toledo            $660.00   Patient Support
Laboratorio Clinico Toledo            $495.00   Patient Support
Laboratorio Clinico Toledo          $2,355.00   Patient Support
Laboratorio Clinico Toledo          $1,200.00   Patient Support
Laboratorio Clinico Toledo          $2,295.00   Patient Support
Laboratorio Clinico Toledo            $915.00   Patient Support
Lake County Haven                  $10,000.00   Charitable Donations
Large Uro Grp Prct Asoc            $20,000.00   Corporate Sponsorship
Large Uro Grp Prct Asoc            $25,000.00   Corporate Sponsorship
Large Uro Grp Prct Asoc            $25,000.00   Corporate Sponsorship
Large Uro Grp Prct Asoc            $25,000.00   Corporate Sponsorship
Large Uro Grp Prct Asoc            $66,400.00   Corporate Sponsorship
Large Uro Grp Prct Asoc            $25,000.00   Corporate Sponsorship
Lenox Hill Hosp                    $10,000.00   Educational Grants
Leukemia and Lymphoma              $10,000.00   Educational Grants
 Society
Leukemia and Lymphoma              $10,000.00   Corporate Sponsorship
 Society
Leukemia and Lymphoma              $15,000.00   Corporate Sponsorship
 Society
Leukemia and Lymphoma               $4,000.00   Corporate Sponsorship
 Society
Leukemia and Lymphoma             $100,000.00   Corporate Sponsorship
 Society
Leukemia and Lymphoma               $2,500.00   Corporate Sponsorship
 Society
Leukemia and Lymphoma             $100,000.00   Charitable Donations
 Society
Leukemia Research                   $5,000.00   Educational Grants
 Foundation Inc.
Leukemia Research                   $5,000.00   Corporate Sponsorship
 Foundation Inc.
Leukemia Research                   $5,000.00   Corporate Sponsorship
 Foundation Inc.
Leukemia Research                  $50,000.00   Fellowships and
 Foundation Inc.                                 Scholarships
Leukemia Research                   $5,000.00   Charitable Donations
 Foundation Inc.
Leukemia Research                   $5,000.00   Educational Grants
 Foundation Inc.
Leukemia Research                  $10,000.00   Corporate Sponsorship
 Foundation Inc.
Living Beyond Breast Cancer        $10,000.00   Corporate Sponsorship
Living Beyond Breast Cancer        $10,000.00   Corporate Sponsorship
Loyola Stritch School of            $2,000.00   Educational Grants
 Medicine Div of
 Dermatology
Lung Cancer Alliance               $25,000.00   Corporate Sponsorship
Lungevity Foundation               $25,000.00   Corporate Sponsorship
Lungevity Foundation               $25,000.00   Corporate Sponsorship
Lupus and Allied Diseases           $6,000.00   Corporate Sponsorship
 Association
Lymphoma Research                   $2,500.00   Corporate Sponsorship
 Foundation
Lymphoma Research                  $10,000.00   Corporate Sponsorship
 Foundation
Lymphoma Research                  $10,000.00   Corporate Sponsorship
 Foundation
Lymphoma Research                   $2,000.00   Corporate Sponsorship
 Foundation
Lymphoma Research                  $37,500.00   Corporate Sponsorship
 Foundation
Magee--Womens Research Inst        $10,000.00   Corporate Sponsorship
 And Fdtn
Magellan Rx Mgmt Inc.              $20,000.00   Corporate Sponsorship
Magic Fdtn                         $15,000.00   Educational Grants
Magic Fdtn                         $10,000.00   Charitable Donations
Massachusetts Association           $5,000.00   Corporate Sponsorship
 for Mental Health
Massachusetts Inst of Tech          $1,000.00   Charitable Donations
Massachusetts Prostate              $2,500.00   Educational Grants
 Cancer Coalition Inc.
Massachusetts Socty for Med         $5,000.00   Educational Grants
 Research
Massachusetts Socty for Med         $5,000.00   Educational Grants
 Research
Massachusetts Socty of              $5,000.00   Corporate Sponsorship
 Clinical Oncologists
Max Foundation                     $45,000.00   Corporate Sponsorship
Mayo Clnc                          $10,000.00   Educational Grants
Mayo Clnc                           $2,500.00   Educational Grants
Mccourt Fdtn Inc.                   $5,000.00   Educational Grants
Me Strong Inc.                      $2,500.00   Corporate Sponsorship
Med--LQ LLC                       $125,000.00   Educational Grants
Med--LQ LLC                       $185,000.00   Educational Grants
Med--LQ LLC                       $150,000.00   Educational Grants
Med--LQ LLC                       $167,933.00   Educational Grants
Med Colg of Wisconsin               $7,500.00   Educational Grants
Med Colg of Wisconsin              $85,000.00   Educational Grants
Med Colg of Wisconsin               $2,000.00   Corporate Sponsorship
Med Colg of Wisconsin              $10,000.00   Educational Grants
Med Conference Planners            $10,000.00   Corporate Sponsorship
Med Learning Inst                 $180,000.00   Educational Grants
Med Learning Inst                  $72,015.00   Educational Grants
Med Learning Inst                 $100,000.00   Educational Grants
Med Learning Inst                  $65,000.00   Educational Grants
Med Learning Inst                  $70,000.00   Educational Grants
Med Learning Inst                  $40,000.00   Educational Grants
Med Learning Inst                 $150,000.00   Educational Grants
Med Learning Inst                  $65,380.00   Educational Grants
Med Learning Inst                 $125,000.00   Educational Grants
Medicinal And Bioorganic            $5,000.00   Educational Grants
 Chemistry Fdtn The
Medscape LLC                      $450,000.00   Educational Grants
Medscape LLC                      $200,000.00   Educational Grants
Medscape LLC                      $189,500.00   Educational Grants
Medscape LLC                      $250,000.00   Educational Grants
Medscape LLC                      $252,350.00   Educational Grants
Medscape LLC                      $175,000.00   Educational Grants
Medscape LLC                      $135,000.00   Educational Grants
Medscape LLC                      $100,000.00   Educational Grants
Medscape LLC                      $385,000.00   Educational Grants
Medscape LLC                      $350,000.00   Educational Grants
Medscape LLC                      $150,000.00   Educational Grants
Medscape LLC                      $100,000.00   Educational Grants
Medscape LLC                      $165,000.00   Educational Grants
Medscape LLC                      $195,000.00   Educational Grants
Medscape LLC                       $65,000.00   Educational Grants
Medscape LLC                       $41,000.00   Educational Grants
Medscape LLC                      $250,000.00   Educational Grants
Medscape LLC                      ($2,000.00)   Educational Grants
Medscape LLC                      $300,000.00   Educational Grants
Medscape LLC                      $112,500.00   Educational Grants
Medstar Washington Hosp Ctr        $10,000.00   Educational Grants
Meeting Designs LLC                $25,000.00   Corporate Sponsorship
Memorial Sloan Kettering           $10,000.00   Educational Grants
 Cancer Ctr
Memphis Business Grp On             $5,120.00   Corporate Sponsorship
 Hlth
Memphis Business Grp On             $5,120.00   Corporate Sponsorship
 Hlth
Meridian Hospitals                    $400.00   Corporate Sponsorship
 Corporation
Methodist Hosp The                 $25,000.00   Corporate Sponsorship
Metropolitan Chicago Breast        $10,000.00   Charitable Donations
 Cancer
Michael J Fox Fdtn                  $1,000.00   Corporate Sponsorship
Michael J Fox Fdtn                 $25,000.00   Corporate Sponsorship
Michael J Fox Fdtn                 $50,000.00   Corporate Sponsorship
Michael J Fox Fdtn                 $15,000.00   Educational Grants
Michigan Parkinson                  $2,000.00   Corporate Sponsorship
 Foundation
Michigan Parkinson                  $4,000.00   Corporate Sponsorship
 Foundation
Michigan Parkinson                  $2,500.00   Corporate Sponsorship
 Foundation
Michigan Rheumatism Socty           $5,000.00   Corporate Sponsorship
Michigan Rheumatism Socty           $5,000.00   Corporate Sponsorship
Michigan Rheumatism Socty           $5,000.00   Corporate Sponsorship
Michigan State Univ                 $1,000.00   Charitable Donations
Michigan State Univ                 $1,000.00   Charitable Donations
Midwest Business Grp On             $5,000.00   Corporate Sponsorship
 Hlth
Midwest Pediatric Endocrine         $6,300.00   Corporate Sponsorship
 Socty
Miles for Cystic Fibrosis          $20,000.00   Charitable Donations
Miles for Cystic Fibrosis           $5,000.00   Corporate Sponsorship
Missouri Hepatitis C               $25,000.00   Charitable Donations
 Alliance
Montana Asoc of Hlth Care           $2,000.00   Corporate Sponsorship
 Purchaser
Montefiore Med Ctr                 $75,000.00   Educational Grants
Montefiore Med Ctr                 $50,000.00   Educational Grants
Montefiore Med Ctr                 $50,000.00   Educational Grants
Mount Sinai School of              $95,000.00   Educational Grants
 Medicine
Mount Sinai School of              $40,000.00   Educational Grants
 Medicine
Mount Sinai School of              $15,000.00   Educational Grants
 Medicine
Mount Sinai School of             $100,000.00   Educational Grants
 Medicine
Mount Sinai School of               $2,500.00   Educational Grants
 Medicine
Mount Sinai School of               $5,000.00   Educational Grants
 Medicine
Mount Sinai School of              $40,000.00   Educational Grants
 Medicine
Mount Sinai School of               $1,500.00   Educational Grants
 Medicine
Mount Sinai School of              $30,000.00   Corporate Sponsorship
 Medicine
Mount Sinai School of              $15,000.00   Educational Grants
 Medicine
Mount Sinai School of               $1,500.00   Educational Grants
 Medicine
Movement Disorder Socty The        $20,000.00   Corporate Sponsorship
Movement Disorder Socty The        $25,000.00   Corporate Sponsorship
Movement Disorder Socty The         $9,900.00   Corporate Sponsorship
Ms Cure Fund, Inc.                 $10,000.00   Educational Grants
Ms Cure Fund, Inc.                 $50,000.00   Educational Grants
Ms Cure Fund, Inc.                 $15,000.00   Educational Grants
Ms Views And News Inc.              $9,000.00   Educational Grants
Multiple Myeloma Research          $20,000.00   Educational Grants
 Fdtn Inc. The
Multiple Myeloma Research          $50,000.00   Educational Grants
 Fdtn Inc. The
Multiple Myeloma Research          $40,000.00   Corporate Sponsorship
 Fdtn Inc. The
Nashville Cares Inc.                $8,000.00   Corporate Sponsorship
National Alliance of Mental         $5,000.00   Corporate Sponsorship
 Illness Flordia
National Alliance of Mental        $15,000.00   Corporate Sponsorship
 Illness Michigan
National Alliance of Mental         $5,000.00   Corporate Sponsorship
 Illness Tennessee
National Alliance of Mental         $5,000.00   Corporate Sponsorship
 Illness Washington
National Alliance of State         $30,000.00   Corporate Sponsorship
 and Territorial AIDS
 Directors
National Association of             $6,750.00   Corporate Sponsorship
 Hispanic Nurses
National Association of             $6,750.00   Corporate Sponsorship
 Hispanic Nurses
National Association of            $25,000.00   Corporate Sponsorship
 Latino Elected & Appointed
 officials Educational Fund
National Brain Tumor               $15,000.00   Corporate Sponsorship
 Society (Nbts)
National Brain Tumor               $50,000.00   Charitable Donations
 Society (Nbts)
National Brain Tumor               $25,000.00   Corporate Sponsorship
 Society, Inc
National Coalition for             $40,000.00   Corporate Sponsorship
 Cancer
National Comprehensive             $15,000.00   Corporate Sponsorship
 Cancer Network
National Comprehensive             $10,000.00   Corporate Sponsorship
 Cancer Network
National Comprehensive             $15,000.00   Corporate Sponsorship
 Cancer Network
National Comprehensive             $10,000.00   Corporate Sponsorship
 Cancer Network
National Comprehensive             $15,000.00   Corporate Sponsorship
 Cancer Network
National Hemophlia                  $5,000.00   Corporate Sponsorship
 Foundation
National Minority Quality          $10,000.00   Corporate Sponsorship
 forum Inc.
National Ms Society Upper           $2,500.00   Corporate Sponsorship
 Midwest Chapter
National Multiple Sclerosis       $250,000.00   Corporate Sponsorship
 Society
National Parkinson                  $2,500.00   Corporate Sponsorship
 Foundation Minnesota
National Parkinson                  $2,500.00   Corporate Sponsorship
 Foundation Minnesota
National Parkinson                  $1,000.00   Corporate Sponsorship
 Foundation Minnesota
National Parkinson                  $2,500.00   Corporate Sponsorship
 Foundation Minnesota
Nationwide Childrens Hosp           $5,000.00   Corporate Sponsorship
 Fdtn
Natl Academy of Dermatology        $30,000.00   Corporate Sponsorship
 Nurse Practitioners
Natl Aids Treatment               $300,000.00   Charitable Donations
 Advocacy Project
Natl Alliance of State And        $100,000.00   Charitable Donations
 Territorial Aids Directors
Natl Asoc of Managed Care          $30,000.00   Educational Grants
 Phys
Natl Asoc of Managed Care          $45,000.00   Educational Grants
 Phys
Natl Asoc of Managed Care          $40,000.00   Educational Grants
 Phys
Natl Asoc of Managed Care          $25,000.00   Corporate Sponsorship
 Phys
Natl Asoc of Managed Care          $35,000.00   Educational Grants
 Phys
Natl Breast Cancer                  $5,000.00   Charitable Donations
 Coalition Fund
Natl Business Coalition On         $50,000.00   Corporate Sponsorship
 Hlth
Natl Commission On                 $10,000.00   Educational Grants
 Correctional Hlth Care
Natl Commission On                  $7,500.00   Corporate Sponsorship
 Correctional Hlth Care
Natl Commission On                  $7,500.00   Corporate Sponsorship
 Correctional Hlth Care
Natl Committee for Quality        $100,000.00   Corporate Sponsorship
 Assurance
Natl Committee for Quality         $95,000.00   Educational Grants
 Assurance
Natl Comprehensive Cancer          $50,000.00   Charitable Donations
 Ntwrk
Natl Comprehensive Cancer          $40,000.00   Corporate Sponsorship
 Ntwrk
Natl Comprehensive Cancer          $50,000.00   Educational Grants
 Ntwrk
Natl Comprehensive Cancer           $5,000.00   Educational Grants
 Ntwrk
Natl Comprehensive Cancer          $25,000.00   Educational Grants
 Ntwrk
Natl Comprehensive Cancer          $25,000.00   Charitable Donations
 Ntwrk
Natl Comprehensive Cancer          $50,000.00   Educational Grants
 Ntwrk
Natl Comprehensive Cancer          $50,000.00   Corporate Sponsorship
 Ntwrk
Natl Comprehensive Cancer          $50,000.00   Educational Grants
 Ntwrk
Natl Comprehensive Cancer          $40,000.00   Educational Grants
 Ntwrk
Natl Comprehensive Cancer         $240,000.00   Corporate Sponsorship
 Ntwrk
Natl Comprehensive Cancer          $75,000.00   Educational Grants
 Ntwrk
Natl Multiple Sclerosis            $10,000.00   Corporate Sponsorship
 Socty
Natl Organization of                $5,000.00   Corporate Sponsorship
 Rheumlgy Managers
Natl Pancreas Fdtn                $200,000.00   Educational Grants
Natl Pancreas Fdtn                 $85,000.00   Educational Grants
Natl Pancreas Fdtn                 $85,000.00   Charitable Donations
Natl Pancreas Fdtn                 $75,000.00   Charitable Donations
Natl Pancreas Fdtn                 $70,000.00   Educational Grants
Natl Pancreas Fdtn                  $1,000.00   Corporate Sponsorship
Natl Pancreas Fdtn                 $75,000.00   Corporate Sponsorship
Natl Pancreas Fdtn                  $7,500.00   Corporate Sponsorship
Natl Pancreas Fdtn                  $2,500.00   Corporate Sponsorship
Natl Pancreas Fdtn                $200,000.00   Educational Grants
Natl Pancreas Fdtn                 $25,000.00   Corporate Sponsorship
Natl Pancreas Fdtn                 $75,000.00   Corporate Sponsorship
Natl Parkinson Fdtn Inc.           $75,000.00   Corporate Sponsorship
Natl Parkinson Fdtn Inc.            $2,500.00   Corporate Sponsorship
Natl Parkinson Fdtn Inc.            $5,000.00   Corporate Sponsorship
Natl Parkinson Fdtn Inc.            $2,500.00   Corporate Sponsorship
Natl Parkinson Fdtn Inc.            $1,000.00   Corporate Sponsorship
Natl Parkinson Fdtn Inc.            $1,500.00   Corporate Sponsorship
Natl Parkinson Fdtn Inc.           $10,000.00   Corporate Sponsorship
Natl Parkinson Fdtn Inc.           $50,000.00   Educational Grants
Natl Parkinson Fdtn Inc.           $10,000.00   Corporate Sponsorship
Natl Parkinson Fdtn Inc.           $85,000.00   Corporate Sponsorship
Natl Psoriasis Fdtn                $25,000.00   Corporate Sponsorship
Natl Psoriasis Fdtn                $75,000.00   Educational Grants
Natl Psoriasis Fdtn                $50,000.00   Educational Grants
Natl Psoriasis Fdtn                $30,000.00   Educational Grants
Natl Psoriasis Fdtn                $26,000.00   Corporate Sponsorship
Natl Psoriasis Fdtn                $26,000.00   Corporate Sponsorship
Natl Psoriasis Fdtn                $26,000.00   Corporate Sponsorship
Natl Psoriasis Fdtn                $26,000.00   Corporate Sponsorship
Natl Psoriasis Fdtn                $20,000.00   Corporate Sponsorship
Natl Psoriasis Fdtn                $10,000.00   Corporate Sponsorship
Natl Psoriasis Fdtn                $13,550.00   Charitable Donations
Natl Psoriasis Fdtn                $50,000.00   Educational Grants
Natl Psoriasis Fdtn                $20,000.00   Corporate Sponsorship
Natl Psoriasis Fdtn                $50,000.00   Corporate Sponsorship
Natl Psoriasis Fdtn                $50,000.00   Corporate Sponsorship
Natl Psoriasis Fdtn                $40,000.00   Corporate Sponsorship
Natl Psoriasis Fdtn                 $2,500.00   Corporate Sponsorship
Natl Psoriasis Fdtn               $150,000.00   Corporate Sponsorship
Natl Psoriasis Fdtn                $20,000.00   Corporate Sponsorship
Natl Psoriasis Fdtn               $100,000.00   Corporate Sponsorship
Natl Psoriasis Fdtn                $40,000.00   Corporate Sponsorship
Natl Psoriasis Fdtn                $30,000.00   Corporate Sponsorship
Natl Psoriasis Fdtn                $20,000.00   Corporate Sponsorship
Natl Socty for Cutaneous           $50,000.00   Corporate Sponsorship
 Medicine
Natl Socty for Cutaneous           $75,000.00   Corporate Sponsorship
 Medicine
Natl Socty for Cutaneous          $135,000.00   Corporate Sponsorship
 Medicine
Natl Socty for Cutaneous          $135,000.00   Corporate Sponsorship
 Medicine
Neuro Challenge Foundation          $7,500.00   Educational Grants
 Inc.
Neurologic Disease                  $4,995.00   Educational Grants
 Foundation
New Jersey Academy of             $105,000.00   Educational Grants
 Family Phys
New Mexico Parkinsons               $3,500.00   Educational Grants
 Disease Coalition
New York Academy of Scnc            $1,500.00   Educational Grants
New York Academy of Scnc            $1,500.00   Educational Grants
New York Socty for                  $2,000.00   Corporate Sponsorship
 Gastrointestinal Endoscopy
New York State Council of          $11,500.00   Corporate Sponsorship
 Hlth-System Pharmacists
New York State Rheumlgy            $18,000.00   Corporate Sponsorship
 Socty
New York Univ School of            $20,000.00   Educational Grants
 Medicine
New York Univ School of            $10,000.00   Educational Grants
 Medicine
New York Univ School of             $5,000.00   Educational Grants
 Medicine
New York Univ School of             $5,000.00   Educational Grants
 Medicine
New York Univ School of            $10,000.00   Educational Grants
 Medicine
New York Univ School of            $10,000.00   Educational Grants
 Medicine
New York Univ School of            $20,000.00   Educational Grants
 Medicine
Nexus Global Grp Scnc              $10,000.00   Corporate Sponsorship
Nicole Jarvis Md Parkinsons         $1,000.00   Corporate Sponsorship
 Research Fdtn
NL Communications Inc.             $50,000.00   Educational Grants
NL Communications Inc.             $35,000.00   Educational Grants
NL Communications Inc.             $40,000.00   Educational Grants
NL Communications Inc.             $50,000.00   Educational Grants
NL Communications Inc.             $15,000.00   Educational Grants
NL Communications Inc.             $50,000.00   Educational Grants
NL Communications Inc.             $50,000.00   Educational Grants
NL Communications Inc.            $100,000.00   Educational Grants
NL Communications Inc.             $50,000.00   Educational Grants
NL Communications Inc.             $10,000.00   Educational Grants
NL Communications Inc.             $25,000.00   Educational Grants
NL Communications Inc.             $25,000.00   Educational Grants
NL Communications Inc.             $40,000.00   Educational Grants
NL Communications Inc.             $25,000.00   Educational Grants
NL Communications Inc.           ($40,000.00)   Educational Grants
NL Communications Inc.            $128,000.00   Educational Grants
NL Communications Inc.            $125,000.00   Educational Grants
NL Communications Inc.             $75,000.00   Educational Grants
NL Communications Inc.             $65,000.00   Educational Grants
NL Communications Inc.             $50,000.00   Educational Grants
NL Communications Inc.             $35,000.00   Educational Grants
NL Communications Inc.             $25,000.00   Educational Grants
NL Communications Inc.             $20,000.00   Educational Grants
North American Ctr for            $390,000.00   Educational Grants
 Continuing Med Education
 (NACCME, LLC)
North American Ctr for             $90,000.00   Educational Grants
 Continuing Med Education
 (NACCME, LLC)
North American Ctr for             $90,000.00   Educational Grants
 Continuing Med Education
 (NACCME, LLC)
North American Ctr for            $100,000.00   Educational Grants
 Continuing Med Education
 (NACCME, LLC)
North American Socty for           $31,000.00   Educational Grants
 Pediatric Gastro
 Hepatology And Nutrition
North American Socty for           $40,000.00   Fellowships and
 Pediatric Gastro                                Scholarships
 Hepatology And Nutrition
North Dakota Pharmacists            $2,500.00   Corporate Sponsorship
 Asoc
North Dakota Society of             $1,750.00   Corporate Sponsorship
 Health System Pharmacists
North Eastern Section of            $3,000.00   Corporate Sponsorship
 The American Chemical
 Society, Inc.
North Memorial Commty Fdtn          $2,500.00   Corporate Sponsorship
Northeast Business Grp On           $5,000.00   Corporate Sponsorship
 Hlth
Northeast Business Grp On           $5,000.00   Corporate Sponsorship
 Hlth
Northwest Health Law                $1,000.00   Corporate Sponsorship
 Advocates
Northwest Kdny Centers              $2,500.00   Corporate Sponsorship
Northwest Parkinsons Fdtn           $7,000.00   Educational Grants
Northwest Parkinsons Fdtn           $5,000.00   Corporate Sponsorship
Northwest Parkinsons Fdtn           $5,000.00   Educational Grants
Northwestern Memorial Fdtn          $8,000.00   Educational Grants
Northwestern Univ                  $25,000.00   Corporate Sponsorship
Northwestern Univ                  $50,000.00   Fellowships and
                                                 Scholarships
Northwestern Univ                   $5,000.00   Educational Grants
Northwestern Univ                   $5,000.00   Educational Grants
Northwestern Univ                   $2,000.00   Educational Grants
Norton Hlthcr Inc.                  $3,000.00   Corporate Sponsorship
Ocular Immunology And               $2,500.00   Corporate Sponsorship
 Uveitis Fdtn
Ohio Asoc of Rheumlgy              $10,000.00   Corporate Sponsorship
Ohio Gastro Socty                   $5,000.00   Corporate Sponsorship
Omnia Education Inc.               $95,000.00   Educational Grants
Oncology Nursing Socty             $15,000.00   Educational Grants
Oncology Nursing Socty             $38,500.00   Corporate Sponsorship
Open Doors Commty School            $2,000.00   Charitable Donations
Oregon Hlth & Scnc Univ            $10,000.00   Educational Grants
Oregon Hlth & Scnc Univ             $2,000.00   Educational Grants
Oregon Hlth & Scnc Univ             $5,000.00   Educational Grants
Oregon Hlth & Scnc Univ            $10,000.00   Educational Grants
Oregon State University             $7,500.00   Corporate Sponsorship
 Foundation
Organic Reactions Catalysis         $1,000.00   Educational Grants
 Socty
Ostomy Asoc of Greater              $1,000.00   Corporate Sponsorship
 Chicago
Ounce of Prevention Fund           $10,000.00   Charitable Donations
Pacific Dermatologic Asoc          $10,000.00   Corporate Sponsorship
Pacific Dermatologic Asoc          $20,000.00   Corporate Sponsorship
Pack Hlth LLC                      $91,375.00   Educational Grants
Pack Hlth LLC                     $175,000.00   Educational Grants
Pack Hlth LLC                     $127,800.00   Educational Grants
Pack Hlth LLC                     $108,875.00   Educational Grants
Pancreas Club The                  $10,000.00   Educational Grants
Pancreatic Cancer Action            $1,250.00   Corporate Sponsorship
 Ntwrk Inc.
Pancreatic Cancer Action            $1,250.00   Corporate Sponsorship
 Ntwrk Inc.
Pancreatic Cancer Action           $25,000.00   Corporate Sponsorship
 Ntwrk Inc.
Pancreatic Cancer Action          $234,000.00   Corporate Sponsorship
 Ntwrk Inc.
Park Nicollet                       $1,000.00   Corporate Sponsorship
Parkinson Alliance Inc.             $1,000.00   Corporate Sponsorship
Parkinson And Movement             $15,000.00   Educational Grants
 Disorder All
Parkinson And Movement              $1,250.00   Corporate Sponsorship
 Disorder All
Parkinson And Movement             $50,000.00   Educational Grants
 Disorder All
Parkinson Asoc of The               $8,000.00   Educational Grants
 Rockies
Parkinson Asoc of The               $6,000.00   Educational Grants
 Rockies
Parkinson Association of              $500.00   Corporate Sponsorship
 Alabama
Parkinson Association of              $500.00   Corporate Sponsorship
 Central Florida Inc.
Parkinson Council                  $20,000.00   Corporate Sponsorship
Parkinson Fdtn of The Natl         $10,000.00   Educational Grants
 Capital Area
Parkinson Foundation of             $1,000.00   Corporate Sponsorship
 Oklahoma
Parkinson Foundation of             $1,500.00   Corporate Sponsorship
 Oklahoma
Parkinson Institute                 $5,000.00   Corporate Sponsorship
Parkinson Ntwrk of Arizona          $2,500.00   Corporate Sponsorship
Parkinson Society of                  $500.00   Corporate Sponsorship
 Greenville Area
Parkinson Study Group              $10,000.00   Educational Grants
Parkinson Support Center of         $2,500.00   Corporate Sponsorship
 Kentuciana
Parkinson Support Center of         $5,000.00   Corporate Sponsorship
 Kentuciana
Parkinson Wellness Recovery         $1,000.00   Corporate Sponsorship
Parkinsons And Movement             $2,500.00   Corporate Sponsorship
 Disorder Foundation
Parkinsons Asoc of Western          $1,500.00   Corporate Sponsorship
 Michigan
Parkinsons Disease Fdtn            $25,000.00   Educational Grants
Parkinsons Disease Fdtn            $50,000.00   Educational Grants
Parkinsons Disease Fdtn             $7,500.00   Corporate Sponsorship
Parkinsons Outreach                 $1,000.00   Corporate Sponsorship
 Association
Parkinsons Resources of             $5,000.00   Corporate Sponsorship
 Oregon
Parkinsons Resources of             $5,000.00   Corporate Sponsorship
 Oregon
Parkinsons Unity Walk              $50,000.00   Corporate Sponsorship
Parkinsons Unity Walk              $64,000.00   Corporate Sponsorship
Partners Hlthcr System           ($10,000.00)   Educational Grants
Partnership for A Drug Free        $50,000.00   Charitable Donations
 America
Partnership for Quality Med         $2,000.00   Charitable Donations
 Donations Pqmd
Partnership for Quality Med         $1,000.00   Charitable Donations
 Donations Pqmd
Patient Access Ntwrk Fdtn       $8,400,000.00   Charitable Donations
Patient Access Ntwrk Fdtn         $260,000.00   Charitable Donations
Patient Access Ntwrk Fdtn         $557,000.00   Charitable Donations
Patient Empowerment Ntwrk          $75,000.00   Educational Grants
Patient Empowerment Ntwrk          $40,000.00   Educational Grants
Patient Empowerment Ntwrk          $22,500.00   Educational Grants
Patient Empowerment Ntwrk          $20,000.00   Educational Grants
Patient Empowerment Ntwrk          $22,500.00   Educational Grants
Patient Empowerment Ntwrk          $35,000.00   Educational Grants
Patient Empowerment Ntwrk          $20,000.00   Educational Grants
Patient Empowerment Ntwrk          $35,000.00   Educational Grants
Patient Empowerment Ntwrk          $10,000.00   Educational Grants
Patient Power LLC                  $90,000.00   Corporate Sponsorship
Pediatric Endocrinology             $6,000.00   Corporate Sponsorship
 Nursing Socty
Pediatric Endocrinology            $10,000.00   Charitable Donations
 Nursing Socty
Pediatric Splts of Virginia         $2,000.00   Corporate Sponsorship
 LLC
Pennsylvania Academy of            $13,550.00   Corporate Sponsorship
 Dermatology And
 Dermatologic Surgry
Pennsylvania Socty of              $10,000.00   Corporate Sponsorship
 Gastro
Pennsylvania State Univ            $15,000.00   Educational Grants
Pennsylvania State Univ            $15,000.00   Educational Grants
Pennsylvania State Univ          ($36,337.33)   Educational Grants
Pennsylvania State Univ            $20,000.00   Educational Grants
Phmcy Quality Alliance             $12,500.00   Educational Grants
Phoenix Childrens Hosp              $1,000.00   Corporate Sponsorship
Phys Education Resource            $25,000.00   Educational Grants
Phys Education Resource            $75,000.00   Educational Grants
Phys Education Resource            $25,000.00   Educational Grants
Phys Education Resource            $25,000.00   Educational Grants
Phys Education Resource            $25,000.00   Educational Grants
Phys Education Resource            $50,000.00   Educational Grants
Phys Education Resource            $50,000.00   Educational Grants
Phys Education Resource            $50,000.00   Educational Grants
Phys Education Resource            $75,000.00   Educational Grants
Phys Education Resource            $50,000.00   Educational Grants
Pins for Parkinsons                   $500.00   Corporate Sponsorship
Pittsburgh Business Grp On          $3,800.00   Corporate Sponsorship
 Hlth
Pittsburgh Business Grp On          $3,800.00   Corporate Sponsorship
 Hlth
President And Fellows of            $6,000.00   Educational Grants
 Harvard Colg
Prevent Cancer Fdtn                $25,000.00   Charitable Donations
Prime Education Inc.              $100,000.00   Educational Grants
Prime Education Inc.              $200,000.00   Educational Grants
Prime Education Inc.              $218,348.25   Educational Grants
Prime Education Inc.              $500,000.00   Educational Grants
Prime Education Inc.              $200,000.00   Educational Grants
Prime Oncology Inc.                $85,000.00   Educational Grants
Prime Oncology Inc.               $142,376.00   Educational Grants
Prime Oncology Inc.                $50,000.00   Educational Grants
Prime Oncology Inc.                $75,000.00   Educational Grants
Prime Oncology Inc.                $85,000.00   Educational Grants
Princeton Univ Trustees            $50,000.00   Fellowships and
                                                 Scholarships
Proce Inc.                         $15,000.00   Educational Grants
Project Access Now                  $3,500.00   Corporate Sponsorship
Project Inform Inc.                $75,000.00   Charitable Donations
Project Inform Inc.                $30,000.00   Corporate Sponsorship
Projects In Knowledge Inc.        $100,000.00   Educational Grants
Promedica International Cme        $15,000.00   Educational Grants
Promis Hlth Organization            $5,000.00   Educational Grants
Prostate Cancer Foundation          $4,000.00   Corporate Sponsorship
 Chicago
Prostate Cancer Research           $10,000.00   Educational Grants
 Inst
Prostate Cancer Research           $15,000.00   Corporate Sponsorship
 Inst
Prostate Hlth Education            $15,000.00   Educational Grants
 Ntwrk
Prostate Hlth Education            $10,000.00   Educational Grants
 Ntwrk
Prostate Net Inc. The              $15,000.00   Educational Grants
Prostaware                          $1,000.00   Corporate Sponsorship
Puerto Rico Academy of             $16,000.00   Corporate Sponsorship
 Family Phys
Puerto Rico Asoc of Gastro         $15,000.00   Educational Grants
Puerto Rico Asoc of Gastro         $30,000.00   Corporate Sponsorship
Puerto Rico Asoc of Gastro          $6,500.00   Educational Grants
Purdue Univ                       $200,000.00   Educational Grants
Purdue Univ                       $250,000.00   Educational Grants
Purdue Univ                      ($60,000.00)   Educational Grants
Regents of The Univ of             $10,000.00   Educational Grants
 California The
Regents of The Univ of              $5,000.00   Educational Grants
 California The
Regents of The Univ of             $40,000.00   Fellowships and
 California The                                  Scholarships
Regents of The Univ of              $5,000.00   Educational Grants
 California The
Regents of The Univ of             $15,000.00   Educational Grants
 California The
Regents of The Univ of             $50,000.00   Fellowships and
 California The                                  Scholarships
Regents of The Univ of              $2,500.00   Educational Grants
 California The
Regents of The Univ of             $10,000.00   Educational Grants
 California The
Regents of The Univ of              $5,000.00   Educational Grants
 Michigan
Regents of The Univ of             $10,000.00   Corporate Sponsorship
 Michigan
Regents of The Univ of              $1,000.00   Educational Grants
 Michigan
Regional Osteopathic Med          $165,000.00   Educational Grants
 Education
Renal Phys Asoc                    $30,000.00   Corporate Sponsorship
Respiratory Hlth Asoc of            $4,050.00   Corporate Sponsorship
 Metro Chicago
Rheumatism Socty of The            $15,000.00   Corporate Sponsorship
 District of Columbia The
Rheumatology Association of         $5,000.00   Corporate Sponsorship
 Nevada
Rheumlgy Alliance of               $25,000.00   Corporate Sponsorship
 Louisiana
Rheumlgy Nurses Socty              $80,000.00   Educational Grants
Rheumlgy Nurses Socty              $31,875.00   Corporate Sponsorship
Rheumlgy Nurses Socty               $5,000.00   Corporate Sponsorship
Rheumlgy Nurses Socty              $25,000.00   Educational Grants
Rheumlgy Nurses Socty              $44,625.00   Corporate Sponsorship
Riverside Medical Clinic            $7,500.00   Educational Grants
 Charitable Foundation
Robert Michael Educational        $123,500.00   Educational Grants
 Inst LLC
Robert Michael Educational         $80,000.00   Educational Grants
 Inst LLC
Rock Steady Boxing                    $500.00   Corporate Sponsorship
Rocky Mountain Ms Center            $5,000.00   Educational Grants
Rush Univ Med Ctr                  $50,000.00   Educational Grants
Rush Univ Med Ctr                  $75,000.00   Educational Grants
Rush Univ Med Ctr                  $35,000.00   Educational Grants
Rutgers The State Univ of          $60,000.00   Educational Grants
 New Jersey
Rutgers The State Univ of          $25,000.00   Educational Grants
 New Jersey
Rutgers The State Univ of          $50,000.00   Educational Grants
 New Jersey
Rutgers University                  $1,500.00   Educational Grants
 Foundation
Safety Pharmacology Socty           $2,000.00   Educational Grants
Saint Anthony Hosp Fdtn             $1,500.00   Educational Grants
San Francisco Neuro Socty           $1,500.00   Educational Grants
San Francisco Retina                $5,000.00   Educational Grants
 Foundation
San Juan Bautista Med              $40,000.00   Fellowships and
                                                 Scholarships
Scott And White Healthcare          $1,000.00   Corporate Sponsorship
 Foundation
Scripps Hlth                        $5,000.00   Educational Grants
Scripps Hlth                       $50,000.00   Educational Grants
Scripps Hlth                        $5,000.00   Educational Grants
Scripps Hlth                        $5,000.00   Educational Grants
Scripps Hlth                       $50,000.00   Educational Grants
Scripps Hlth                       $25,000.00   Educational Grants
Scripps Research Inst.              $5,000.00   Fellowships and
                                                 Scholarships
Scripps Research Inst.              $2,000.00   Educational Grants
Seattle Science Foundation          $7,500.00   Educational Grants
Sexual Medicine Socty of         ($25,000.00)   Educational Grants
 North Am
Sexual Medicine Socty of          $225,000.00   Corporate Sponsorship
 North America Inc.
Share                              $10,000.00   Patient Support
Sheknows LLC                       $43,000.00   Corporate Sponsorship
Smith Wholesale Drug                $9,000.00   Corporate Sponsorship
 Company
Sociedad Dermatologica De          $15,000.00   Corporate Sponsorship
 Puerto Rico
Sociedad Dermatologica De          $35,000.00   Corporate Sponsorship
 Puerto Rico
Sociedad Pr Endocrinologia         $15,000.00   Corporate Sponsorship
 Y Diabetologia
Sociedad Puertorriquena             $8,000.00   Corporate Sponsorship
 Pediatria
Society for Mucosal                 $1,500.00   Educational Grants
 Immunology
Society for Neuro-Oncology         $10,000.00   Educational Grants
Society for Neuro-Oncology        $107,400.00   Corporate Sponsorship
Society for Neuro-Oncology         $25,000.00   Corporate Sponsorship
Society of Nuclear Medicine         $5,000.00   Corporate Sponsorship
 and Molecular Imaging
Socty for Immunotherapy of          $5,000.00   Educational Grants
 Cancer
Socty for Leukocyte Biology         $1,500.00   Educational Grants
Socty for Neuroscience              $2,500.00   Educational Grants
Socty for Translational            $10,000.00   Educational Grants
 Oncology
Socty of Dermatology Phys          $45,000.00   Corporate Sponsorship
 Assistants
Socty of Dermatology Phys          $20,000.00   Corporate Sponsorship
 Assistants
Socty of Dermatology Phys          $40,000.00   Corporate Sponsorship
 Assistants
Socty of Investigative             $30,000.00   Educational Grants
 Dermatology
Socty of Toxicologic                $1,000.00   Corporate Sponsorship
 Pathology
Socty of Toxicologic               $15,000.00   Corporate Sponsorship
 Pathology
Socty of Toxicology                   $450.00   Corporate Sponsorship
Socty of Toxicology                 $2,500.00   Corporate Sponsorship
South Carolina Alliance of          $5,000.00   Corporate Sponsorship
 Hlth Plans
South Carolina                      $5,000.00   Corporate Sponsorship
 Dermatological Asoc
South Dakota Parkinson                $500.00   Corporate Sponsorship
 Foundation
South Texas Asoc of                $40,000.00   Corporate Sponsorship
 Rheumatologists
Southeastern Consortium for        $10,000.00   Corporate Sponsorship
 Dermatology
Splty Pharma Education Ctr         $49,750.00   Educational Grants
St Louise Regional Hosp           ($2,000.00)   Educational Grants
State of Maryland                  $40,000.00   Fellowships and
                                                 Scholarships
State of Maryland                   $5,500.00   Educational Grants
State of Maryland                  $23,000.00   Educational Grants
Super Jake Fdtn The                $25,000.00   Charitable Donations
Susan G Komen Philadelphia          $3,500.00   Educational Grants
Take A Breather Foundation         $10,000.00   Corporate Sponsorship
Take A Breather Foundation          $2,500.00   Corporate Sponsorship
Take A Breather Foundation         $15,000.00   Corporate Sponsorship
Tarsus Cardio Inc. Dba             $35,000.00   Corporate Sponsorship
 South Beach Symposium
Team Fox North Texas                $1,000.00   Corporate Sponsorship
Tennessee Dermatology Socty         $4,000.00   Corporate Sponsorship
Tennessee Disability                $5,000.00   Corporate Sponsorship
 Coalition
Tennessee Disability                $2,500.00   Corporate Sponsorship
 Coalition
Tennessee Nurses                    $6,000.00   Corporate Sponsorship
 Association
Teratology Socty                    $2,000.00   Corporate Sponsorship
Texas Academy of Family             $2,500.00   Corporate Sponsorship
 Physicians
Texas Medical Association           $3,000.00   Corporate Sponsorship
Texas Medical Association          $10,000.00   Corporate Sponsorship
Texas Neuro Socty                   $5,000.00   Corporate Sponsorship
Texas Osteopathic Medical           $3,000.00   Corporate Sponsorship
 Association
Texas Urological Socty              $4,500.00   Corporate Sponsorship
Texas Urological Socty              $4,500.00   Corporate Sponsorship
The Endocrine Socty                $25,000.00   Educational Grants
The Endocrine Socty                $25,000.00   Educational Grants
The Endocrine Socty                $25,000.00   Educational Grants
The International Psoriasis        $25,000.00   Educational Grants
 Council
Trinity Christian Colg Asoc         $1,000.00   Charitable Donations
Trustees of The Univ of            $10,000.00   Educational Grants
 Pennsylvania
Tufts Med Ctr                       $2,500.00   Corporate Sponsorship
Tufts Univ                        ($4,580.00)   Educational Grants
Tulane Univ Hlth Scnc Ctr          $20,000.00   Corporate Sponsorship
UC Regents Maxillofacial           $20,000.00   Educational Grants
 Prosthetics Clnc
UC Regents Maxillofacial           $10,000.00   Educational Grants
 Prosthetics Clnc
UC Regents Maxillofacial           $40,000.00   Fellowships and
 Prosthetics Clnc                                Scholarships
UC Regents Maxillofacial            $5,000.00   Educational Grants
 Prosthetics Clnc
UC Regents Maxillofacial           $15,000.00   Educational Grants
 Prosthetics Clnc
Ultimate Med Academy Med          $150,000.00   Educational Grants
 Learning Grp LLC
Ultimate Med Academy Med          $198,790.00   Educational Grants
 Learning Grp LLC
Ultimate Med Academy Med           $98,600.00   Educational Grants
 Learning Grp LLC
Ultimate Med Academy Med          $389,100.00   Educational Grants
 Learning Grp LLC
UMA Education Inc. DBA             $90,000.00   Educational Grants
 Global Education Grp
Umass Amherst                       $5,000.00   Corporate Sponsorship
Umass Fdtn                          $2,500.00   Charitable Donations
United Spinal Association          $75,000.00   Corporate Sponsorship
 Inc.
United States Adult Cystic          $7,500.00   Educational Grants
 Fibrosis Asoc Inc.
United Way of Ctrl                  $1,250.00   Corporate Sponsorship
 Massachusetts
United Way of Ctrl                  $5,000.00   Corporate Sponsorship
 Massachusetts
Univ Connecticut Derm              $12,000.00   Fellowships and
                                                 Scholarships
Univ Connecticut Derm               ($130.91)   Fellowships and
                                                 Scholarships
Univ Hlth Srvc At Stony            $20,000.00   Educational Grants
 Point Inc.
Univ Hosp Cleveland Med            $15,000.00   Fellowships and
                                                 Scholarships
Univ Hosp of Brooklyn              $16,000.00   Educational Grants
Univ of Alabama At                  $8,000.00   Educational Grants
 Birmingham
Univ of Alabama At                 $40,000.00   Fellowships and
 Birmingham                                      Scholarships
Univ of California--San            $50,000.00   Fellowships and
 Francisco                                       Scholarships
Univ of California--San             $5,000.00   Educational Grants
 Francisco
Univ of California--San            $10,000.00   Educational Grants
 Francisco
Univ of California Berkeley        $20,000.00   Educational Grants
Univ of California Berkeley        $45,000.00   Corporate Sponsorship
Univ of California Berkeley        $50,000.00   Corporate Sponsorship
Univ of California Irvine           $5,000.00   Fellowships and
                                                 Scholarships
Univ of California Irvine           $5,000.00   Educational Grants
Univ of Chicago                    $10,000.00   Charitable Donations
Univ of Chicago                    $10,000.00   Educational Grants
Univ of Cincinnati                 $85,000.00   Educational Grants
Univ of Cincinnati                 $75,000.00   Educational Grants
Univ of Cincinnati                 $60,000.00   Educational Grants
Univ of Cincinnati                $250,000.00   Educational Grants
Univ of Cincinnati                $130,000.00   Educational Grants
Univ of Cincinnati                 $30,000.00   Educational Grants
Univ of Colorado Denver             $3,500.00   Educational Grants
 School of Medicine
Univ of Florida                    $15,898.00   Educational Grants
Univ of Florida                    $75,000.00   Educational Grants
Univ of Florida Fdtn                  $500.00   Corporate Sponsorship
Univ of Florida Fdtn               $40,000.00   Fellowships and
                                                 Scholarships
Univ of Illinios                   $40,000.00   Fellowships and
                                                 Scholarships
Univ of Illinois Fdtn               $1,000.00   Charitable Donations
Univ of Illinois Fdtn               $1,000.00   Charitable Donations
Univ of Kansas Hosp                $50,000.00   Fellowships and
                                                 Scholarships
Univ of Kansas Hosp                $45,000.00   Educational Grants
Univ of Louisville Research        $75,000.00   Educational Grants
 Fdtn
Univ of Louisville Research        $15,000.00   Educational Grants
 Fdtn
Univ of Louisville Research         $5,000.00   Educational Grants
 Fdtn
Univ of Louisville Research         $1,500.00   Educational Grants
 Fdtn
Univ of Maryland Baltimore          $5,000.00   Fellowships and
                                                 Scholarships
Univ of Maryland Baltimore          $1,000.00   Charitable Donations
 Fdtn
Univ of Massachusetts Med           $1,000.00   Charitable Donations
 School
Univ of Massachusetts Med           $2,500.00   Educational Grants
 School
Univ of Minnesota Regents           $1,500.00   Educational Grants
Univ of Minnesota Regents           $1,000.00   Educational Grants
Univ of Nebraska Med Ctr           $20,000.00   Educational Grants
Univ of Nebraska Med Ctr            $7,500.00   Educational Grants
------------------------------------------------------------------------


                      Grants Donations Report--2017
    (Parentheses represent refunds of previously disclosed payments)
                         Report as of 3/31/2018
------------------------------------------------------------------------
         Recipient             Payment Amount            Purpose
------------------------------------------------------------------------
50 Hoops                           $10,000.00   Educational Grants
A and R Educational Group           $4,500.00   Corporate Sponsorships
 LLC
A and R Educational Group          $20,000.00   Corporate Sponsorships
 LLC
Academia Medica Del Sur             $8,000.00   Corporate Sponsorships
Academia Puertorriquena DE          $3,000.00   Corporate Sponsorships
 Neurologia
Academy of Managed Care            $25,000.00   Corporate Sponsorships
 Pharmacy
Academy of Managed Care            $15,000.00   Corporate Sponsorships
 Pharmacy
Academy of Physician                $2,500.00   Corporate Sponsorships
 Assistants, Tennessee
Advanced Urology Institute         $10,000.00   Corporate Sponsorships
 Education and General Fund
Advances in Cosmetic and           $75,000.00   Corporate Sponsorships
 Med Dermatology Inc.
Advances in Cosmetic and          $100,000.00   Corporate Sponsorships
 Med Dermatology Inc.
Advances in Cosmetic and           $75,000.00   Corporate Sponsorships
 Med Dermatology Inc.
Advocate Bromenn Medical            $2,000.00   Educational Grants
 Center
Advocate Bromenn Medical            $2,500.00   Educational Grants
 Center
Aesthetic Dermatology              $35,000.00   Corporate Sponsorships
 Symposia
Aesthetic Dermatology              $25,000.00   Corporate Sponsorships
 Symposia
AIDS Connecticut                    $2,500.00   Corporate Sponsorships
AIDS Connecticut                    $2,500.00   Corporate Sponsorships
AIDS Foundation of Chicago         $25,000.00   Charitable Donations
AIDS Institute                     $36,000.00   Corporate Sponsorships
Alabama Dermatology Society        $50,000.00   Corporate Sponsorships
Alabama Dermatology Society        $50,000.00   Corporate Sponsorships
Alaska Rheumatology                 $5,000.00   Corporate Sponsorships
 Alliance
Alliance for Aging Research         $5,000.00   Corporate Sponsorships
Alliance for Patient Access        $30,000.00   Corporate Sponsorships
Alzheimers Association             $10,000.00   Corporate Sponsorships
 Greater Illinois Chapter
Alzheimers Association              $2,500.00   Corporate Sponsorships
 Greater Illinois Chapter
Alzheimers Association              $5,000.00   Corporate Sponsorships
 Greater Illinois Chapter
Alzheimers Disease and            $133,750.00   Corporate Sponsorships
 Related Disorders
 Association Inc.
American Academy of                $50,000.00   Charitable Donations
 Dermatology
American Academy of                $65,000.00   Corporate Sponsorships
 Dermatology
American Academy of                $35,000.00   Corporate Sponsorships
 Dermatology
American Academy of                $25,000.00   Charitable Donations
 Dermatology
American Academy of                $40,000.00   Educational Grants
 Dermatology
American Academy of                $25,000.00   Corporate Sponsorships
 Dermatology
American Academy of                $15,000.00   Charitable Donations
 Dermatology
American Academy of                $37,500.00   Corporate Sponsorships
 Dermatology
American Academy of                $50,000.00   Educational Grants
 Dermatology
American Academy of               $300,000.00   Corporate Sponsorships
 Dermatology
American Academy of Family         $17,000.00   Educational Grants
 Physicians
American Academy of                $75,000.00   Corporate Sponsorships
 Neurology Institute
American Academy of                $30,000.00   Educational Grants
 Neurology Institute
American Academy of                $53,400.00   Corporate Sponsorships
 Neurology Institute
American Academy of                $50,000.00   Fellowships and
 Neurology Institute                             Scholarships
American Academy of                $30,000.00   Corporate Sponsorships
 Neurology Institute
American Academy of                $14,000.00   Corporate Sponsorships
 Pediatrics
American Academy of                $10,000.00   Educational Grants
 Physician Assistants
American Academy of                $16,000.00   Educational Grants
 Physician Assistants
American Association of            $20,000.00   Corporate Sponsorships
 Clinical Endocrinologists
 New Jersey Chapter
American Association of            $18,000.00   Educational Grants
 Clinical Endocrinologists
 New Jersey Chapter
American Association of            $10,000.00   Corporate Sponsorships
 Physicians of Indian
 Origin Arkansas
American Association of            $10,000.00   Corporate Sponsorships
 Physicians of Indian
 Origin Arkansas
American Association for          ($2,205.00)   Educational Grants
 Accreditation of
 Laboratory Animal Care
 International
American Association for           $25,000.00   Fellowships and
 Cancer Research                                 Scholarships
American Association for           $25,000.00   Educational Grants
 Cancer Research
American Association for           $25,000.00   Educational Grants
 Cancer Research
American Association for           $10,000.00   Educational Grants
 Cancer Research
American Association for           $25,000.00   Charitable Donations
 Cancer Research
American Association for           $10,000.00   Educational Grants
 Cancer Research
American Association for           $25,000.00   Educational Grants
 Cancer Research
American Association for           $25,000.00   Educational Grants
 Cancer Research
American Association for           $15,000.00   Educational Grants
 Cancer Research
American Association for           $15,000.00   Educational Grants
 Cancer Research
American Association for           $15,000.00   Educational Grants
 Cancer Research
American Association for           $15,000.00   Educational Grants
 Cancer Research
American Association for           $75,000.00   Educational Grants
 Cancer Research
American Association for           $20,000.00   Charitable Donations
 Laboratory Animal Science
American Association for            $5,000.00   Educational Grants
 Laboratory Animal Science
 New England Branch
American Association for            $3,150.00   Corporate Sponsorships
 The Study of Liver Disease
American Association of             $7,400.00   Corporate Sponsorships
 Gynecologic Laparoscopists
 Inc
American Association of            $59,500.00   Corporate Sponsorships
 Gynecologic Laparoscopists
 Inc
American Association of            $50,000.00   Corporate Sponsorships
 Pharmaceutical Scientists
American Autoimmune Related        $40,000.00   Corporate Sponsorships
American Brain Tumor               $30,000.00   Educational Grants
 Association
American Brain Tumor               $10,000.00   Educational Grants
 Association
American Brain Tumor               $15,000.00   Educational Grants
 Association
American Brain Tumor               $15,000.00   Corporate Sponsorships
 Association
American Brain Tumor                $7,500.00   Corporate Sponsorships
 Association
American Cancer Society            $10,000.00   Corporate Sponsorships
American Cancer Society             $1,500.00   Corporate Sponsorships
American Cancer Society             $3,500.00   Corporate Sponsorships
American Cancer Society            $50,000.00   Corporate Sponsorships
American Cancer Society             $5,000.00   Corporate Sponsorships
 Action Network Connecticut
American Cancer Society             $2,500.00   Corporate Sponsorships
 Action Network North
 Carolina
American Cancer Society             $5,000.00   Corporate Sponsorships
 Cancer Action Network
American Cancer Society             $5,000.00   Corporate Sponsorships
 Cancer Action Network
American Cancer Society            $10,000.00   Corporate Sponsorships
 Cancer Action Network
American Cancer Society             $5,000.00   Corporate Sponsorships
 Cancer Action Network
American Cancer Society             $2,500.00   Corporate Sponsorships
 Cancer Action Network
American Cancer Society            $10,000.00   Corporate Sponsorships
 Cancer Action Network
American Cancer Society             $5,000.00   Corporate Sponsorships
 Cancer Action Network
American Cancer Society             $2,500.00   Corporate Sponsorships
 Cancer Action Network
American Cancer Society             $3,000.00   Corporate Sponsorships
 Cancer Action Network
American Cancer Society             $2,500.00   Corporate Sponsorships
 Cancer Action Network
American Cancer Society             $7,500.00   Corporate Sponsorships
 Cancer Action Network
American Cancer Society             $2,500.00   Corporate Sponsorships
 Cancer Action Network
American Cancer Society             $2,500.00   Corporate Sponsorships
 Cancer Action Network
American Cancer Society             $7,000.00   Corporate Sponsorships
 Cancer Action Network
American Cancer Society            $10,000.00   Corporate Sponsorships
 Cancer Action Network
American Cancer Society             $3,000.00   Corporate Sponsorships
 Cancer Action Network
American Cancer Society            $25,000.00   Corporate Sponsorships
 Cancer Action Network
American Cancer Society             $2,500.00   Corporate Sponsorships
 Cancer Action Network
American Chemist Society            $2,500.00   Educational Grants
American Chemist Society            $1,000.00   Educational Grants
American Chemist Society            $3,000.00   Educational Grants
American College of Chest          $35,000.00   Educational Grants
 Physicians
American College of                 $5,000.00   Educational Grants
 Clinical Pharmacology
American College of                $10,000.00   Patient Support
 Endocrinology
American College of                $15,000.00   Educational Grants
 Gastroenterology
American College of               $100,000.00   Corporate Sponsorships
 Gastroenterology
American College of                $90,000.00   Corporate Sponsorships
 Gastroenterology
American College of                $30,000.00   Charitable Donations
 Laboratory Animal Medicine
American College of                 $5,000.00   Educational Grants
 Obstetricians and
 Gynecologists
American College of                $15,000.00   Corporate Sponsorships
 Osteopathic Obstetricians
 and Gynecologists
American College of                $15,000.00   Corporate Sponsorships
 Osteopathic Obstetricians
 and Gynecologists
American College of                $57,000.00   Corporate Sponsorships
 Physician Foundation
American College of                 $1,000.00   Corporate Sponsorships
 Physicians West Virginia
 Chapter
American College of                $10,000.00   Corporate Sponsorships
 Rheumatology
American College of                $80,000.00   Fellowships and
 Rheumatology                                    Scholarships
American College of                $25,000.00   Educational Grants
 Rheumatology
American College of                $20,000.00   Educational Grants
 Rheumatology
American College of                $37,500.00   Educational Grants
 Rheumatology
American College of                $17,600.00   Educational Grants
 Rheumatology
American College of               $150,000.00   Corporate Sponsorships
 Rheumatology
American College of             $2,000,000.00   Corporate Sponsorships
 Rheumatology Research and
 Education Foundation
American College of               $500,000.00   Corporate Sponsorships
 Rheumatology Research and
 Education Foundation
American Congress of               $10,500.00   Corporate Sponsorships
 Obstetricians and
 Gynecologists
American Congress of               $12,500.00   Corporate Sponsorships
 Obstetricians and
 Gynecologists
American Congress of               $12,500.00   Corporate Sponsorships
 Obstetricians and
 Gynecologists
American Congress of               $12,500.00   Corporate Sponsorships
 Obstetricians and
 Gynecologists
American Congress of               $13,250.00   Corporate Sponsorships
 Obstetricians and
 Gynecologists
American Congress of               $50,000.00   Educational Grants
 Obstetricians and
 Gynecologists
American Congress of                $5,000.00   Educational Grants
 Obstetricians and
 Gynecologists
American                           $12,500.00   Charitable Donations
 Gastroenterological
 Association Institute
American                            $5,000.00   Corporate Sponsorships
 Gastroenterological
 Association Institute
American                           $40,000.00   Educational Grants
 Gastroenterological
 Association Institute
American                           $75,000.00   Educational Grants
 Gastroenterological
 Association Institute
American Kidney Fund                $5,000.00   Corporate Sponsorships
American Legion National           $25,000.00   Corporate Sponsorships
American Liver Foundation         $275,000.00   Corporate Sponsorships
American Liver Foundation          $25,000.00   Corporate Sponsorships
American Liver Foundation          $10,000.00   Corporate Sponsorships
American Liver Foundation           $5,000.00   Educational Grants
American Liver Foundation           $5,000.00   Educational Grants
American Liver Foundation           $2,500.00   Corporate Sponsorships
American Liver Foundation           $1,000.00   Corporate Sponsorships
American Liver Foundation           $2,500.00   Corporate Sponsorships
American Liver Foundation           $2,500.00   Corporate Sponsorships
American Liver Foundation           $1,500.00   Corporate Sponsorships
American Lung Association         $100,000.00   Corporate Sponsorships
American Lung Association           $5,000.00   Corporate Sponsorships
 of The Northeast
American Lung Association           $5,000.00   Corporate Sponsorships
 of The Northeast
American Lung Association           $7,500.00   Corporate Sponsorships
 of The Northeast
American Med Group                 $10,000.00   Corporate Sponsorships
 Associate
American Med Group                 $10,000.00   Corporate Sponsorships
 Associate
American Med Group                 $20,000.00   Corporate Sponsorships
 Associate
American Med Group                  $4,940.00   Corporate Sponsorships
 Associate
American Med Group                  $4,940.00   Corporate Sponsorships
 Associate
American Med Group                  $4,940.00   Corporate Sponsorships
 Associate
American Med Group                  $4,940.00   Corporate Sponsorships
 Associate
American Med Group                  $4,940.00   Corporate Sponsorships
 Associate
American Med Group                  $4,940.00   Corporate Sponsorships
 Associate
American Med Group                  $4,940.00   Corporate Sponsorships
 Associate
American Med Group                  $4,940.00   Corporate Sponsorships
 Associate
American Med Group                  $4,940.00   Corporate Sponsorships
 Associate
American Med Group                  $4,940.00   Corporate Sponsorships
 Associate
American Neuro Associate           $40,000.00   Educational Grants
American Pancreatic                $25,000.00   Patient Support
 Associate
American Pancreatic                $75,000.00   Educational Grants
 Associate
American Parkinson Disease         $20,000.00   Educational Grants
 Association
American Parkinson Disease          $3,500.00   Corporate Sponsorships
 Association
American Parkinson Disease         $62,000.00   Corporate Sponsorships
 Association
American Parkinson Disease          $5,500.00   Corporate Sponsorships
 Association
American Parkinson Disease          $3,000.00   Corporate Sponsorships
 Association
American Parkinson Disease          $2,500.00   Corporate Sponsorships
 Association
American Parkinson Disease          $5,000.00   Corporate Sponsorships
 Association
American Red Cross of              $10,000.00   Charitable Donations
 Greater Chicago
American Society for                $2,000.00   Educational Grants
 Pharmacology and
 Experimental Therapeutics
American Society for               $10,000.00   Corporate Sponsorships
 Reproductive Medicine
American Society for                $3,000.00   Corporate Sponsorships
 Reproductive Medicine
American Society for               $15,000.00   Corporate Sponsorships
 Reproductive Medicine
American Society of Colon          $35,000.00   Educational Grants
 and Rectal Surgns
American Society of                $50,000.00   Fellowships and
 Hematology                                      Scholarships
American Society of                $20,000.00   Educational Grants
 Hematology
American Society of                $60,000.00   Educational Grants
 Hematology
American Society of                $50,000.00   Educational Grants
 Hematology
American Society of Nphro          $35,000.00   Corporate Sponsorships
American Society of Nphro         $160,000.00   Educational Grants
American Statistical                $2,000.00   Educational Grants
 Associate
American Statistical                $2,500.00   Educational Grants
 Associate
American Thyroid Associate         $30,000.00   Educational Grants
 Inc.
American Urological                $50,000.00   Charitable Donations
 Associate Education and
 Research Inc.
American Urological                $20,000.00   Educational Grants
 Associate Education and
 Research Inc.
American Urological                $50,000.00   Educational Grants
 Associate Education and
 Research Inc.
American Urological                $50,000.00   Educational Grants
 Associate Education and
 Research Inc.
American Urological                $13,500.00   Corporate Sponsorships
 Associate Inc Western
 Section
American Urological                $25,000.00   Charitable Donations
 Association
American Urological                 $6,000.00   Corporate Sponsorships
 Association
American Urological                 $2,000.00   Corporate Sponsorships
 Association
American Urological                $10,000.00   Corporate Sponsorships
 Association
American Urological                 $6,000.00   Corporate Sponsorships
 Association
American Urological                $10,000.00   Charitable Donations
 Association
American Urological                 $6,000.00   Corporate Sponsorships
 Association
American Urological                 $1,500.00   Corporate Sponsorships
 Association
Americans for Med Progress         $90,000.00   Charitable Donations
Americares Foundation              $12,000.00   Charitable Donations
American Hepato-Pancreato-         $30,000.00   Corporate Sponsorships
 Biliary Association
Angel Foundation                    $2,500.00   Corporate Sponsorships
Arizona State Association           $3,500.00   Corporate Sponsorships
 of Physician Assistants
Arizona United Rheumatology        $25,000.00   Corporate Sponsorships
 Alliance--Aura
Arkansas State Rheumatology        $10,000.00   Corporate Sponsorships
 Association Inc.
Arkansas Technology                 $1,000.00   Charitable Donations
 University Foundation
Arthritis Foundation                $5,000.00   Charitable Donations
Arthritis Foundation                $5,000.00   Educational Grants
Arthritis Foundation                $2,000.00   Corporate Sponsorships
Arthritis Foundation               $30,000.00   Corporate Sponsorships
Arthritis Foundation               $10,000.00   Corporate Sponsorships
Arthritis Foundation                $4,000.00   Educational Grants
Arthritis Foundation                $5,000.00   Educational Grants
Arthritis Foundation               $20,000.00   Educational Grants
Arthritis Foundation               $20,000.00   Educational Grants
Arthritis Foundation                $3,000.00   Educational Grants
Arthritis Foundation               $50,000.00   Corporate Sponsorships
Arthritis Foundation                $2,500.00   Educational Grants
Arthritis Foundation                $2,500.00   Corporate Sponsorships
Arthritis Foundation                $3,000.00   Corporate Sponsorships
Arthritis Foundation               $10,000.00   Corporate Sponsorships
Arthritis Foundation                $2,500.00   Corporate Sponsorships
Arthritis Foundation                $3,000.00   Corporate Sponsorships
Arthritis Foundation                $2,000.00   Corporate Sponsorships
Arthritis Foundation               $50,000.00   Corporate Sponsorships
Arthritis Foundation                $5,000.00   Educational Grants
Arthritis Foundation              $250,000.00   Corporate Sponsorships
Arthritis Foundation              $300,000.00   Corporate Sponsorships
Arthritis Foundation              $300,000.00   Corporate Sponsorships
Arthritis Foundation              $259,000.00   Corporate Sponsorships
Arthritis Foundation Inc.          $50,000.00   Corporate Sponsorships
Arthritis Patient Services          $2,400.00   Educational Grants
Arthritis Patient Services          $5,000.00   Educational Grants
Arthritis Patient Services         $65,000.00   Educational Grants
ARVO Foundation for Eye             $5,000.00   Fellowships and
 Research                                        Scholarships
ASCO Cancer Foundation            $100,000.00   Patient Support
ASCO Cancer Foundation             $20,000.00   Educational Grants
ASCO Cancer Foundation             $28,000.00   Educational Grants
ASCO Cancer Foundation             $10,000.00   Educational Grants
ASCO Cancer Foundation             $10,000.00   Educational Grants
ASCO Cancer Foundation             $15,000.00   Educational Grants
ASCO Cancer Foundation             $15,000.00   Educational Grants
ASCO Cancer Foundation             $15,000.00   Educational Grants
ASCO Cancer Foundation             $30,000.00   Educational Grants
ASCO Cancer Foundation             $30,000.00   Educational Grants
ASCO Cancer Foundation             $30,000.00   Educational Grants
ASCO Cancer Foundation             $56,000.00   Educational Grants
ASCO Cancer Foundation             $60,000.00   Educational Grants
ASCO Cancer Foundation             $75,000.00   Educational Grants
ASCO Cancer Foundation             $34,500.00   Corporate Sponsorships
ASCO Cancer Foundation             $13,275.00   Educational Grants
ASCO Cancer Foundation             $26,000.00   Educational Grants
Asembia                            $60,000.00   Corporate Sponsorships
ASHP Foundation                    $75,000.00   Fellowships and
                                                 Scholarships
Associate DE                       $10,000.00   Corporate Sponsorships
 Gastroenterologia Y
 Hepatologia Pediatrica DE
 Puerto Rico Aghppr
Associate DE Reumatologos           $7,500.00   Corporate Sponsorships
 DE Puerto Rico
Associate DE Reumatologos          $15,000.00    Corporate Sponsorships
 DE Puerto Rico
Associate of Physician             $25,000.00   Corporate Sponsorships
 Assistants in Oncology
 Inc.
Associate of Physician              $7,500.00   Corporate Sponsorships
 Assistants in Oncology
 Inc.
Associate of Physician              $7,500.00   Corporate Sponsorships
 Assistants in Oncology
 Inc.
Associate of Professors of         $50,000.00   Corporate Sponsorships
 Gyn and Obstetrician
Associate of Professors of          $5,000.00   Corporate Sponsorships
 Gyn and Obstetrician
Associate of Professors of         $75,000.00   Educational Grants
 Gyn and Obstetrician
Associate of Reproductive          $50,000.00   Educational Grants
 Health Professionals
Associate of Univ                   $5,000.00   Corporate Sponsorships
 Technology Managers
Association of Community           $15,000.00   Corporate Sponsorships
 Cancer Centers (ACCC)
Association of Community          $150,000.00   Corporate Sponsorships
 Cancer Centers (ACCC)
Association of Women in            $40,000.00   Corporate Sponsorships
 Rheumatology
Association of Women in            $30,000.00   Corporate Sponsorships
 Rheumatology
Association of Women in            $75,000.00   Corporate Sponsorships
 Rheumatology
Atlanta Dermatology and            $10,000.00   Corporate Sponsorships
 Pathology Associates, PC
Autoimmune Advocacy                 $3,000.00   Corporate Sponsorships
 Alliance
Auxiliary of Robert Wood            $5,000.00   Corporate Sponsorships
 Johnson University
 Hospital
Baehr Challenge Ltd                 $1,000.00   Corporate Sponsorships
Ball State University               $1,000.00   Charitable Donations
 Foundation
Baylor College Medicine             $5,000.00   Educational Grants
 Infusion Dis
Baylor College Medicine             $3,600.00   Fellowships and
 Infusion Dis                                    Scholarships
Baylor Health Care System          $40,000.00   Fellowships and
 Foundation                                      Scholarships
Baylor Scott and White              $5,000.00   Educational Grants
 Health
Baylor Scott and White             $30,000.00   Educational Grants
 Health
Bendcare                          $410,000.00   Corporate Sponsorships
Beth Israel Deaconess            ($16,526.70)   Educational Grants
 Medical Center
Beth Israel Deaconess              $40,000.00   Fellowships and
 Medical Center                                  Scholarships
Beth Israel Deaconess              $30,000.00   Fellowships and
 Medical Center                                  Scholarships
Beth Israel Deaconess              $35,000.00   Fellowships and
 Medical Center                                  Scholarships
Beth Israel Deaconess              $40,000.00   Fellowships and
 Medical Center                                  Scholarships
Beth Israel Deaconess               $3,000.00   Educational Grants
 Medical Center
Beth Israel Deaconess             ($1,751.70)   Educational Grants
 Medical Center
Beth Israel Med Center             $25,000.00   Fellowships and
                                                 Scholarships
Bioconnections LLC                 $50,000.00   Corporate Sponsorships
Biotechnology Industry              $8,000.00   Corporate Sponsorships
 Organization
Board of Trustees of The            $3,000.00   Corporate Sponsorships
 Leland Stanford Junior
 Univ
Board of Trustees of The            $1,500.00   Educational Grants
 Univ of Illinois
Bonnie J Addario Lung               $5,000.00   Corporate Sponsorships
 Cancer Foundation
Bonnie J Addario Lung              $25,000.00   Corporate Sponsorships
 Cancer Foundation
Boomer Esiason Foundation          $25,000.00   Corporate Sponsorships
Borland Groover Clinic              $1,000.00   Corporate Sponsorships
Borland Groover Clinic                $750.00   Corporate Sponsorships
Borland Groover Clinic              $1,000.00   Corporate Sponsorships
Boston College School of            $7,500.00   Corporate Sponsorships
 Nursing
Boston Society Inc.                 $3,000.00   Educational Grants
Boston Taiwanese                    $2,500.00   Educational Grants
 Biotechnology Association
 Inc.
Brain Support Network Inc.          $5,000.00   Educational Grants
Breast Friends                      $1,000.00   Corporate Sponsorships
Breastcancer.Org                    $5,000.00   Educational Grants
Brian Grant Foundation            $150,000.00   Educational Grants
Brian Grant Foundation              $1,500.00   Corporate Sponsorships
Brigham and Women's                 $7,000.00   Educational Grants
 Hospital, Inc.
Brigham and Women's                $40,000.00   Fellowships and
 Hospital, Inc.                                  Scholarships
Broad Institute                     $5,000.00   Corporate Sponsorships
California Associate of             $3,500.00   Corporate Sponsorships
 Physician Groups
California Associate of            $25,000.00   Corporate Sponsorships
 Physician Groups
California Chronic Care            $25,000.00   Corporate Sponsorships
 Coalition
California Chronic Care            $10,000.00   Corporate Sponsorships
 Coalition
California Life Sciences            $5,000.00   Corporate Sponsorships
 Association
California Life Sciences            $5,500.00   Corporate Sponsorships
 Association
California Neurology                $5,000.00   Educational Grants
 Society
California Neurology                $5,000.00   Educational Grants
 Society
California Society of              $10,000.00   Corporate Sponsorships
 Dermatology and
 Dermatology Surgry
California Society of              $10,000.00   Corporate Sponsorships
 Dermatology and
 Dermatology Surgry
California Society of              $10,000.00   Corporate Sponsorships
 Dermatology and
 Dermatology Surgry
Cancer and Leukemia Group B        $50,000.00   Educational Grants
 Foundation
Cancer and Leukemia Group B        $30,000.00   Educational Grants
 Foundation
Cancer and Leukemia Group B        $50,000.00   Educational Grants
 Foundation
Cancer Awareness of Nevada          $1,000.00   Corporate Sponsorships
Cancer Care                        $10,000.00   Educational Grants
Cancer Care                        $50,000.00   Charitable Donations
Cancer Care                        $15,000.00   Educational Grants
Cancer Care                        $25,000.00   Educational Grants
Cancer Care                       $100,000.00   Corporate Sponsorships
Cancer Care                       $150,000.00   Educational Grants
Cancer Care                       $150,000.00   Educational Grants
Cancer Care                        $90,000.00   Educational Grants
Cancer Care                        $50,000.00   Educational Grants
Cancer Care                       $100,000.00   Educational Grants
Cancer Care                        $65,000.00   Corporate Sponsorships
Cancer Molecular Thrpt              $5,000.00   Educational Grants
Cancer Support Community           $75,000.00   Educational Grants
Cancer Support Community           $25,000.00   Educational Grants
Cancer Support Community           $50,000.00   Educational Grants
Cancer Wellness Center              $5,000.00   Corporate Sponsorships
Cardinal Health                   $170,000.00   Corporate Sponsorships
Cardinal Health                    $60,000.00   Corporate Sponsorships
Caribe Gyn                          $5,000.00   Corporate Sponsorships
Caribe Gyn                         $17,000.00   Corporate Sponsorships
Caring Ambassadors Program         $75,000.00   Charitable Donations
 Inc.
Caring Ambassadors Program         $15,000.00   Patient Support
 Inc.
Carti Foundation                   $10,000.00   Corporate Sponsorships
Cascade AIDS Project                $5,000.00   Corporate Sponsorships
Cedars--Sinai Med Center           $40,000.00   Fellowships and
                                                 Scholarships
Cedars--Sinai Med Center           $10,000.00   Educational Grants
Central Brain Tumor                $25,000.00   Educational Grants
 Registry of The United
 States
Central Brain Tumor                $25,000.00   Educational Grants
 Registry of The United
 States
Central Savannah River Area         $1,000.00   Corporate Sponsorships
 Csra Parkinson Support
 Group
Chicago Urological Soctiey         $12,000.00   Corporate Sponsorships
Childrens Hospital Corp             $5,000.00   Educational Grants
Childrens Hospital of              $10,000.00   Corporate Sponsorships
 Philadelphia
Childrens Treehouse                $10,000.00   Patient Support
 Foundation
Chimp Haven                        $20,000.00   Charitable Donations
Chinese American Society of         $5,000.00   Corporate Sponsorships
 Nuclear Medicine and
 Molecular Imaging
Chris Elliott Fund                 $10,000.00   Charitable Donations
Chris Elliott Fund                 $10,000.00   Charitable Donations
Chris Elliott Fund                 $10,000.00   Charitable Donations
Chris Elliott Fund                  $5,000.00   Charitable Donations
Chris Elliott Fund                  $5,000.00   Charitable Donations
Chronic Liver Disease              $50,000.00   Corporate Sponsorships
 Foundation
Chronic Liver Disease             $300,000.00   Educational Grants
 Foundation
Chronic Liver Disease             $200,000.00   Educational Grants
 Foundation
Chronic Liver Disease             $247,350.00   Educational Grants
 Foundation
Chronic Liver Disease             $226,945.00   Educational Grants
 Foundation
Chronic Liver Disease              $25,000.00   Corporate Sponsorships
 Foundation
Chronic Lymphocytic                $75,000.00   Corporate Sponsorships
 Leukemia Society Inc.
Chronic Lymphoytic Leukemia        $22,825.00   Educational Grants
 Society Inc.
Chronic Lymphoytic Leukemia        $50,000.00   Charitable Donations
 Society Inc.
Chronic Lymphoytic Leukemia        $75,000.00   Educational Grants
 Society Inc.
Chronic Lymphoytic Leukemia        $50,000.00   Educational Grants
 Society Inc.
Chronic Lymphoytic Leukemia        $50,000.00   Educational Grants
 Society Inc.
Cincinnati Childrens               $40,000.00   Fellowships and
 Hospital Medical Center                         Scholarships
Cincinnati Childrens               $25,000.00   Corporate Sponsorships
 Hospital Medical Center
City of Hope National Med           $5,000.00   Corporate Sponsorships
 Center
Cleveland Clinic                   $65,000.00   Educational Grants
Cleveland Clinic                   $65,000.00   Educational Grants
Cleveland Clinic                    $5,000.00   Educational Grants
Cleveland Clinic                   $10,000.00   Corporate Sponsorships
Cleveland Clinic                   $50,000.00   Educational Grants
Cleveland Clinic                   $20,000.00   Corporate Sponsorships
Cleveland Clinic                    $5,000.00   Educational Grants
Cleveland Clinic                   $55,000.00   Fellowships and
                                                 Scholarships
Cleveland Clinic                   $40,000.00   Fellowships and
                                                 Scholarships
Cleveland Clinic                  ($4,853.56)   Educational Grants
 Educational Foundation
Cleveland Clinic                    $5,000.00   Educational Grants
 Educational Foundation
Cleveland Clinic                   $15,000.00   Educational Grants
 Educational Foundation
Cleveland Clinic                    $5,000.00   Educational Grants
 Educational Foundation
Cleveland Clinic                    $2,500.00   Educational Grants
 Educational Foundation
Cleveland Clinic                    $5,000.00   Educational Grants
 Educational Foundation
Cleveland Clinic                    $5,000.00   Educational Grants
 Educational Foundation
Cleveland Clinic                   $15,000.00   Educational Grants
 Educational Foundation
Cleveland Clinic                  ($6,652.23)   Educational Grants
 Educational Foundation
Cleveland Clinic                  ($5,410.94)   Educational Grants
 Educational Foundation
Cleveland Clinic                   $65,000.00   Educational Grants
 Educational Foundation
Cleveland Clinic Minority          $40,000.00   Fellowships and
 Mens Health Center                              Scholarships
Clinical Care Optn LLC             $50,000.00   Educational Grants
Clinical Care Optn LLC             $50,000.00   Educational Grants
Clinical Care Optn LLC             $60,000.00   Educational Grants
Clinical Care Optn LLC             $25,000.00   Educational Grants
Clinical Care Optn LLC             $95,560.00   Educational Grants
Clinical Care Optn LLC             $25,000.00   Educational Grants
Clinical Care Optn LLC             $75,000.00   Educational Grants
Clinical Care Optn LLC             $95,000.00   Educational Grants
Clinical Care Optn LLC            $150,000.00   Educational Grants
Cll Global Research                $35,000.00   Educational Grants
 Foundation
Cll Global Research                $20,000.00   Educational Grants
 Foundation
Cll Global Research                $35,000.00   Educational Grants
 Foundation
Coalition for Prevention of        $10,000.00   Corporate Sponsorships
 Colorectal Cancer in
 Puerto Rico
Coalition of Positive              $40,000.00   Educational Grants
 Health Empowerment
Coalition of Texans With            $5,000.00   Corporate Sponsorships
 Disabilities
Coalition On Positive               $5,000.00   Corporate Sponsorships
 Health Empower
Cockerell Educational              $25,000.00   Corporate Sponsorships
 Foundation
Cody Dieruf Benefit                 $5,000.00   Patient Support
 Foundation
Cold Spring Harbor                  $2,500.00   Educational Grants
 Laboratory
Collaborative Alliance for          $6,000.00   Fellowships and
 Pancreatic Education and                        Scholarships
 Research
Collaborative Alliance for         $30,000.00   Educational Grants
 Pancreatic Education and
 Research
Collaborative Alliance for          $1,750.00   Corporate Sponsorships
 Pancreatic Education and
 Research
Colorado Gerontological             $5,000.00   Corporate Sponsorships
 Society
Columbia Univ Med Center            $5,000.00   Educational Grants
Community Access National           $2,500.00   Corporate Sponsorships
 Network
Community Center                   $15,000.00   Corporate Sponsorships
Community Center                   $10,000.00   Corporate Sponsorships
Community Foundation                $5,000.00   Corporate Sponsorships
Community Foundation                $5,000.00   Corporate Sponsorships
Community Initiatives             $150,000.00   Corporate Sponsorships
Community Initiatives              $30,000.00   Corporate Sponsorships
Community Initiatives              $25,000.00   Corporate Sponsorships
Community Liver Alliance           $20,000.00   Corporate Sponsorships
Community Liver Alliance            $5,000.00   Corporate Sponsorships
Community Liver Alliance            $9,000.00   Corporate Sponsorships
Community Liver Alliance            $3,000.00   Corporate Sponsorships
Community Liver Alliance            $5,000.00   Corporate Sponsorships
Complex Mechanisms of               $1,500.00   Educational Grants
 Disease Aging and Trauma
 (Cmdat) Research
 Foundation
Connecticut Advanced Nurse          $2,000.00   Corporate Sponsorships
 Practitioner Society
Connecticut Advocates for           $2,500.00   Corporate Sponsorships
 Parkinsons
Connecticut Peer Review             $3,000.00   Corporate Sponsorships
 Organization--Qualidigm
Connecting To Cure Crohns          $10,000.00   Corporate Sponsorships
 and Colitis
Consortium of Multiple             $50,000.00   Educational Grants
 Sclerosis Centers
Consortium of Multiple             $55,000.00   Educational Grants
 Sclerosis Centers
Consortium of Multiple             $85,000.00   Educational Grants
 Sclerosis Centers
Continuing Educational             $95,000.00   Educational Grants
 Alliance LLC
Continuing Educational            $149,000.00   Educational Grants
 Alliance LLC
Continuing Educational             $99,550.00   Educational Grants
 Alliance LLC
Continuing Educational            ($1,050.00)   Educational Grants
 Alliance LLC
Continuing Educational            $200,000.00   Educational Grants
 Alliance LLC
Continuing Educational            $121,165.00   Educational Grants
 Alliance LLC
Continuing Med Education           $85,000.00   Educational Grants
 Outfitters LLC
Cornell Univ Weill Med             $15,000.00   Educational Grants
 College
Cornell Univ Weill Med              $3,000.00   Educational Grants
 College
Cornerstone Health                  $3,000.00   Corporate Sponsorships
 Enablement Strategic
 Solutions, LLC
Cornerstone Health Inc.            $75,000.00   Educational Grants
Cornerstone Health Inc.            $50,000.00   Educational Grants
Cradles To Crayons Inc.               $300.00   Charitable Donations
Creighton Univ                     $15,000.00   Educational Grants
Crohns and Colitis                 $25,000.00   Charitable Donations
 Foundation of America
Crohns and Colitis                 $25,000.00   Educational Grants
 Foundation of America
Crohns and Colitis                 $60,000.00   Educational Grants
 Foundation of America
Crohns and Colitis                 $80,000.00   Educational Grants
 Foundation of America
Crohns and Colitis                $200,000.00   Educational Grants
 Foundation of America
Crohns and Colitis                  $3,500.00   Corporate Sponsorships
 Foundation of America
Crohns and Colitis                  $5,000.00   Corporate Sponsorships
 Foundation of America
Crohns and Colitis                  $1,500.00   Corporate Sponsorships
 Foundation of America
Crohns and Colitis                  $3,000.00   Corporate Sponsorships
 Foundation of America
Crohns and Colitis                  $5,000.00   Corporate Sponsorships
 Foundation of America
Crohns and Colitis                 $12,500.00   Corporate Sponsorships
 Foundation of America
Crohns and Colitis                 $14,250.00   Corporate Sponsorships
 Foundation of America
Crohns and Colitis                 $10,000.00   Corporate Sponsorships
 Foundation of America
Crohns and Colitis                  $2,500.00   Corporate Sponsorships
 Foundation of America
Crohns and Colitis                  $1,500.00   Corporate Sponsorships
 Foundation of America
Crohns and Colitis                  $2,500.00   Corporate Sponsorships
 Foundation of America
Crohns and Colitis                 $20,000.00   Corporate Sponsorships
 Foundation of America
Crohns and Colitis                  $2,000.00   Corporate Sponsorships
 Foundation of America
Crohns and Colitis                  $2,500.00   Corporate Sponsorships
 Foundation of America
Crohns and Colitis                  $5,000.00   Corporate Sponsorships
 Foundation of America
Crohns and Colitis                  $2,000.00   Corporate Sponsorships
 Foundation of America
Crohns and Colitis                $150,000.00   Corporate Sponsorships
 Foundation of America
Crohns and Colitis                 $10,000.00   Corporate Sponsorships
 Foundation of America
Crohns and Colitis                  $1,500.00   Corporate Sponsorships
 Foundation of America
Crohns and Colitis                  $1,500.00   Corporate Sponsorships
 Foundation of America
Crohns and Colitis                 $25,000.00   Corporate Sponsorships
 Foundation of America
Crohns and Colitis                  $1,500.00   Corporate Sponsorships
 Foundation of America
Crohns and Colitis                  $2,000.00   Corporate Sponsorships
 Foundation of America
Crohns and Colitis                $100,000.00   Educational Grants
 Foundation of America
Crohns and Colitis                 $15,000.00   Fellowships and
 Foundation of America                           Scholarships
Crohns and Colitis                  $2,500.00   Corporate Sponsorships
 Foundation of America
Crohns and Colitis                 $20,000.00   Charitable Donations
 Foundation of America
Crohns and Colitis                  $2,500.00   Corporate Sponsorships
 Foundation of America
Crohns and Colitis                 $10,000.00   Educational Grants
 Foundation of America
Crohns and Colitis                $150,000.00   Educational Grants
 Foundation of America
Crohns and Colitis                 $25,000.00   Corporate Sponsorships
 Foundation of America
Crohns and Colitis                 $85,000.00   Corporate Sponsorships
 Foundation of America
Crohns and Colitis                $400,000.00   Corporate Sponsorships
 Foundation of America
Cure Cf                             $1,000.00   Corporate Sponsorships
Curepsp Inc.                       $30,000.00   Educational Grants
Curepsp Inc.                       $10,000.00   Educational Grants
Curepsp Inc.                       $20,000.00   Corporate Sponsorships
Curesearch for Childrens           $10,000.00   Charitable Donations
 Cancer
Curesearch for Childrens           $15,000.00   Corporate Sponsorships
 Cancer
Cystic Fibrosis Foundation          $2,500.00   Corporate Sponsorships
Cystic Fibrosis Foundation          $5,000.00   Corporate Sponsorships
Cystic Fibrosis Foundation          $2,500.00   Corporate Sponsorships
Cystic Fibrosis Foundation          $3,000.00   Corporate Sponsorships
Cystic Fibrosis Foundation          $2,000.00   Corporate Sponsorships
Cystic Fibrosis Foundation          $2,000.00   Corporate Sponsorships
Cystic Fibrosis Foundation          $2,500.00   Corporate Sponsorships
Cystic Fibrosis Foundation          $1,000.00   Corporate Sponsorships
Cystic Fibrosis Foundation          $2,000.00   Corporate Sponsorships
Cystic Fibrosis Foundation          $1,500.00   Corporate Sponsorships
Cystic Fibrosis Foundation          $1,000.00   Corporate Sponsorships
Cystic Fibrosis Foundation          $2,500.00   Corporate Sponsorships
Cystic Fibrosis Foundation          $2,500.00   Corporate Sponsorships
Cystic Fibrosis Foundation          $9,000.00   Corporate Sponsorships
Cystic Fibrosis Foundation          $3,500.00   Corporate Sponsorships
Cystic Fibrosis Foundation          $1,500.00   Corporate Sponsorships
Cystic Fibrosis Foundation          $1,500.00   Corporate Sponsorships
Cystic Fibrosis Foundation          $2,500.00   Corporate Sponsorships
Cystic Fibrosis Foundation          $5,000.00   Corporate Sponsorships
Cystic Fibrosis Foundation          $3,000.00   Corporate Sponsorships
Cystic Fibrosis Foundation          $3,000.00   Corporate Sponsorships
Cystic Fibrosis Foundation          $3,000.00   Corporate Sponsorships
Cystic Fibrosis Foundation          $1,000.00   Corporate Sponsorships
Cystic Fibrosis Foundation          $2,500.00   Corporate Sponsorships
Cystic Fibrosis Foundation          $2,500.00   Corporate Sponsorships
Cystic Fibrosis Foundation          $2,500.00   Corporate Sponsorships
Cystic Fibrosis Foundation          $1,000.00   Corporate Sponsorships
Cystic Fibrosis Foundation          $1,500.00   Corporate Sponsorships
Cystic Fibrosis Foundation            $250.00   Corporate Sponsorships
Cystic Fibrosis Foundation          $5,000.00   Corporate Sponsorships
Cystic Fibrosis Foundation          $5,000.00   Corporate Sponsorships
Cystic Fibrosis Foundation          $1,000.00   Corporate Sponsorships
Cystic Fibrosis Foundation          $1,500.00   Corporate Sponsorships
Cystic Fibrosis Foundation          $2,000.00   Corporate Sponsorships
Cystic Fibrosis Foundation            $500.00   Corporate Sponsorships
Cystic Fibrosis Foundation          $2,000.00   Corporate Sponsorships
Cystic Fibrosis Foundation          $6,500.00   Corporate Sponsorships
Cystic Fibrosis Foundation          $3,500.00   Corporate Sponsorships
Cystic Fibrosis Foundation          $5,000.00   Corporate Sponsorships
Cystic Fibrosis Foundation          $2,000.00   Corporate Sponsorships
Cystic Fibrosis Foundation          $7,500.00   Corporate Sponsorships
Cystic Fibrosis Foundation        $750,000.00   Corporate Sponsorships
Cystic Fibrosis Research            $5,000.00   Corporate Sponsorships
 Fund Emilys Entourage
Cystic Fibrosis Research           $10,000.00   Corporate Sponsorships
 Inc.
Cystic Fibrosis Research           $10,000.00   Corporate Sponsorships
 Inc.
Cystic Fibrosis Research           $10,000.00   Corporate Sponsorships
 Inc.
Cystic Fibrosis Research            $3,000.00   Corporate Sponsorships
 Inc.
Cystic Fibrosis Research            $5,000.00   Corporate Sponsorships
 Inc.
Cystic Fibrosis Research            $7,000.00   Corporate Sponsorships
 Inc.
Cystic Fibrosis Research           $18,000.00   Corporate Sponsorships
 Inc.
Cystic Fibrosis Research           $10,000.00   Corporate Sponsorships
 Inc.
Danville D Elegance                 $5,000.00   Corporate Sponsorships
 Foundation
Dava Oncology Lp                   $25,000.00   Corporate Sponsorships
Dava Oncology Lp                   $10,000.00   Corporate Sponsorships
Davis Phinney Foundation            $5,000.00   Corporate Sponsorships
Davis Phinney Foundation           $30,000.00   Educational Grants
Davis Phinney Foundation           $10,000.00   Corporate Sponsorships
Davis Phinney Foundation           $30,000.00   Educational Grants
Davis Phinney Foundation            $2,500.00   Corporate Sponsorships
Davis Phinney Foundation           $20,000.00   Educational Grants
Davis Phinney Foundation           $30,000.00   Educational Grants
DBC Pri-Med LLC                   $165,000.00   Corporate Sponsorships
Deep South Cancer                  $10,000.00   Corporate Sponsorships
 Foundation
Deep South Cancer                   $5,000.00   Corporate Sponsorships
 Foundation
Deep South Cancer                   $5,000.00   Corporate Sponsorships
 Foundation
Dermatology Education              $75,000.00   Corporate Sponsorships
 Foundation
Dermatology Education              $75,000.00   Corporate Sponsorships
 Foundation
Dermatology Education              $50,000.00   Corporate Sponsorships
 Foundation
Dermatology Education              $50,000.00   Corporate Sponsorships
 Foundation
Dermatology Education              $50,000.00   Corporate Sponsorships
 Foundation
Dermatology Foundation            $135,000.00   Charitable Donations
Dermatology Foundation             $50,000.00   Corporate Sponsorships
Dermatology Univ LLC               $75,000.00   Corporate Sponsorships
Digestive Disease Week             $31,500.00   Corporate Sponsorships
Digestive Health Foundation        $25,000.00   Corporate Sponsorships
Diversity and Leadership            $6,000.00   Corporate Sponsorships
 Inc.
Doctor Solomon Carter             ($4,919.07)   Fellowships and
 Fuller Mental Health                            Scholarships
 Center
Donate Life Coalition of           $10,000.00   Charitable Donations
 Michigan
Duke Univ                           $5,000.00   Educational Grants
Duke Univ                        ($16,360.00)   Educational Grants
Eastern Virginia Medical            $5,000.00   Educational Grants
 School
Economic Alliance for               $2,500.00   Corporate Sponsorships
 Michigan
Eicosanoid Research                 $2,500.00   Educational Grants
 Foundation
Eisenhower Desert                  $25,000.00   Educational Grants
 Orthopedic Center
Eisenhower Desert                 $250,000.00   Educational Grants
 Orthopedic Center
Eisenhower Desert                  $50,000.00   Educational Grants
 Orthopedic Center
Eisenhower Desert                  $85,000.00   Educational Grants
 Orthopedic Center
Eisenhower Desert                  $25,000.00   Educational Grants
 Orthopedic Center
Eisenhower Desert                  $30,000.00   Educational Grants
 Orthopedic Center
Eisenhower Desert                  $50,000.00   Educational Grants
 Orthopedic Center
Eisenhower Desert                 $500,000.00   Educational Grants
 Orthopedic Center
El Centro Regional Medical          $6,000.00   Corporate Sponsorships
 Center F
Elsevier Inc.                      $50,000.00   Educational Grants
Employers Health Coalition          $7,500.00   Corporate Sponsorships
Endocrine Society                  $25,000.00   Educational Grants
Endocrine Society                  $50,000.00   Educational Grants
Endocrine Society                  $50,000.00   Corporate Sponsorships
Endocrine Society                  $25,000.00   Educational Grants
Endometriosis Foundation of        $10,000.00   Charitable Donations
 America
Epilepsy Association of            $10,000.00   Corporate Sponsorships
 Central Florida
Epilepsy Foundation                 $5,000.00   Corporate Sponsorships
Escuela DE Medicina DE             $10,000.00   Educational Grants
 Ponce
Excellence in Rheumatology        $100,000.00   Corporate Sponsorships
 Education LLC
Family Med Center                   $7,500.00   Corporate Sponsorships
 Bolingbrook
Federation of American              $2,000.00   Educational Grants
 Society for Experimental
 Biology Faseb
Federation of American              $5,000.00   Corporate Sponsorships
 Society for Experimental
 Biology Faseb
Federation of American              $2,000.00   Corporate Sponsorships
 Society for Experimental
 Biology Faseb
Federation of American              $5,000.00   Corporate Sponsorships
 Society for Experimental
 Biology Faseb
Federation of Clinical             $20,000.00   Educational Grants
 Immunology Society
Federation of Clinical             $25,000.00   Educational Grants
 Immunology Society
Feinstein Institute for Med       $150,000.00   Educational Grants
 Research
Florida Cancer Specialists         $34,500.00   Corporate Sponsorships
 Foundation
Florida Chapter of America          $2,500.00   Corporate Sponsorships
 Academy of Pediatrics
Florida Chapter, American           $5,000.00   Corporate Sponsorships
 College of Phyician
 Services
Florida Hospital Orlando           $10,000.00   Corporate Sponsorships
Florida Society of                 $22,600.00   Corporate Sponsorships
 Dermatology and
 Dermatologic Surgry
Florida Society of                 $25,500.00   Corporate Sponsorships
 Dermatology and
 Dermatologic Surgery
Florida Society of                 $60,000.00   Corporate Sponsorships
 Dermatology Physician
 Assistants Inc.
Florida Society of                 $65,000.00   Corporate Sponsorships
 Dermatology Physician
 Assistants Inc.
Florida Society of                 $35,000.00   Corporate Sponsorships
 Rheumatology
Florida Society of                  $2,500.00   Corporate Sponsorships
 Rheumatology Inc.
Florida Society of                  $3,000.00   Corporate Sponsorships
 Rheumatology Inc.
Focus Med Communications          $150,000.00   Corporate Sponsorships
Focus Med Communications            $5,000.00   Corporate Sponsorships
Foster Ocular Immunology           $33,000.00   Corporate Sponsorships
 Society
Foundation for Biomedical          $50,000.00   Charitable Donations
 Research
Foundation of Consortium of         $5,450.00   Fellowships and
 Multiple Sclerosis Centers                      Scholarships
 Cmsc
Foundation of Consortium of        $32,000.00   Fellowships and
 Multiple Sclerosis Centers                      Scholarships
 Cmsc
Free To Breathe                    $25,000.00   Educational Grants
Free To Breathe                    $50,000.00   Corporate Sponsorships
Free To Breathe                    $40,000.00   Educational Grants
Friends of Cancer Research         $40,000.00   Corporate Sponsorships
Friends of The St Louis            $50,000.00   Corporate Sponsorships
 Univ Liver Center
Fundacion Alfredo Ruiz              $5,000.00   Corporate Sponsorships
Fundacion Daledale Inc.               $500.00   Corporate Sponsorships
Fundacion Puertorriquena DE        $12,500.00   Educational Grants
 Pacientes Consult
 Endometriosis
Funk Zitiello Foundation            $4,000.00   Corporate Sponsorships
Gastrointestinal Research          $50,000.00   Corporate Sponsorships
 Foundation
Gateway for Cancer Research        $10,000.00   Charitable Donations
Geneva Foundation                  $10,000.00   Educational Grants
George Washington Univ              $5,000.00   Corporate Sponsorships
George Washington Univ              $5,000.00   Corporate Sponsorships
 Hospital
George Washington Univ              $3,000.00   Corporate Sponsorships
 Hospital
George Washington Univ             $10,000.00   Corporate Sponsorships
 Hospital
Georgetown Univ                     $7,000.00   Educational Grants
Georgetown Univ                    $50,000.00   Fellowships and
                                                 Scholarships
Georgia Society of                 $50,000.00   Corporate Sponsorships
 Dermatology and
 Dermatologic Surgery
Gildas Club Chicago                $10,000.00   Charitable Donations
Give for A Smile                    $1,000.00   Corporate Sponsorships
Global Academy for Medical         $36,000.00   Corporate Sponsorships
 Education
Global Academy for Medical         $15,000.00   Corporate Sponsorships
 Education
Global Academy for Medical         $90,000.00   Corporate Sponsorships
 Education
Global Academy for Medical         $35,000.00   Corporate Sponsorships
 Education
Global Academy for Medical         $58,500.00   Corporate Sponsorships
 Education
Global Academy for Medical         $76,500.00   Corporate Sponsorships
 Education
Global Healthy Living              $75,000.00   Corporate Sponsorships
 Foundation
Global Healthy Living              $75,000.00   Corporate Sponsorships
 Foundation
Global Healthy Living             $150,000.00   Corporate Sponsorships
 Foundation
Global Oncology                     $5,000.00   Corporate Sponsorships
Global Resource for                $25,000.00   Educational Grants
 Advancing Cancer Education
Global Virus Network Inc.           $7,500.00   Educational Grants
Global Virus Network Inc.           $8,000.00   Educational Grants
Good Grief                            $500.00   Corporate Sponsorships
Gordon Research Conferences         $2,000.00   Educational Grants
Gordon Research Conferences         $2,000.00   Educational Grants
Gordon Research Conferences         $2,000.00   Educational Grants
Gordon Research Conferences         $2,500.00   Educational Grants
Gordon Research Conferences         $2,500.00   Educational Grants
Gordon Research Conferences         $2,500.00   Educational Grants
Gordon Research Conferences         $3,000.00   Educational Grants
Gordon Research Conferences         $2,000.00   Educational Grants
Gordon Research Conferences         $2,500.00   Educational Grants
Gordon Research Conferences         $2,500.00   Educational Grants
Gordon Research Conferences         $2,000.00   Educational Grants
Gordon Research Conferences         $2,500.00   Educational Grants
Gordon Research Conferences         $2,500.00   Educational Grants
Great Lakes Chapter of The          $1,000.00   Corporate Sponsorships
 American Society for
 Pharmacology and
 Experimental Therapeutics
Group for Research and             $15,000.00   Corporate Sponsorships
 Assessment of Psoriasis
 and Psoriatic Arthritis
Grupo de Apoyo de Ninos y           $1,000.00   Corporate Sponsorships
 Adolescentes Consult
 Reumatologia
Grupo de Apoyo de Ninos y           $3,000.00   Corporate Sponsorships
 Adolescentes Consult
 Reumatologia
Gynecologic Oncology Group         $40,000.00   Educational Grants
Gynecologic Oncology Group         $25,000.00   Educational Grants
H Lee Moffitt Cancer Center         $5,000.00   Educational Grants
 and Research Institute
H Lee Moffitt Cancer Center         $7,500.00   Educational Grants
 and Research Institute
Halo House Foundation               $5,000.00   Corporate Sponsorships
Harborside Press                   $38,000.00   Corporate Sponsorships
Harborside Press                   $20,000.00   Corporate Sponsorships
Healthcare 21 Business             $16,000.00   Corporate Sponsorships
 Coalition
Healthcare 21 Business              $1,000.00   Corporate Sponsorships
 Coalition
Healthy Women                      $30,000.00   Corporate Sponsorships
Healthy Women                      $45,000.00   Corporate Sponsorships
Heart to Heart                     $10,000.00   Charitable Donations
 International Inc.
Heb Grocery Co Lp                   $7,000.00   Corporate Sponsorships
Hematology Oncology                 $5,000.00   Educational Grants
 Pharmacy Associate
Hematology Oncology                 $5,000.00   Educational Grants
 Pharmacy Associate
Henry Ford Health System            $5,000.00   Educational Grants
Henry M Jackson Foundation         $10,000.00   Educational Grants
Hep C Connection                   $10,000.00   Corporate Sponsorships
Hepatitis C Association            $25,000.00   Educational Grants
Hepatitis C Association            $20,000.00   Educational Grants
Hepatitis C Mentor and             $10,000.00   Educational Grants
 Support Group The
Hepatitis Education Project       $100,000.00   Charitable Donations
Hidradenitis Suppurativa           $27,500.00   Corporate Sponsorships
 Foundation
Hitchcock Foundation              ($2,685.00)   Educational Grants
Hitchcock Foundation                $8,000.00   Educational Grants
Hitchcock Foundation               $20,000.00   Educational Grants
Hitchcock Foundation                $8,000.00   Educational Grants
HMP Communications                 $10,000.00   Corporate Sponsorships
HMP Communications                 $60,000.00   Corporate Sponsorships
Hope Foundation                    $40,000.00   Fellowships and
                                                 Scholarships
Hope Foundation                    $25,000.00   Educational Grants
Hospital of the University         $60,000.00   Educational Grants
 of Pennsylvania
Hospital of the University          $5,000.00   Educational Grants
 of Pennsylvania
Hospital of the University         $10,000.00   Educational Grants
 of Pennsylvania
Houston Area Parkinson              $5,000.00   Corporate Sponsorships
 Society
Houston Business Coalition         $11,000.00   Corporate Sponsorships
 On Health
Howard Brown Health Center          $2,500.00   Corporate Sponsorships
Howard Hanna Children's            $10,000.00   Charitable Donations
 Free Care Fund
Hubbard Street Dance               $20,000.00   Educational Grants
 Chicago
Human Growth Foundation            $10,000.00   Corporate Sponsorships
Human Growth Foundation            $10,000.00   Corporate Sponsorships
Humboldt--Del Norte County          $4,000.00   Educational Grants
 Medical Society
IBD Horizons                       $80,000.00   Educational Grants
IBD Horizons                        $4,000.00   Corporate Sponsorships
IBD Horizons                       $25,000.00   Corporate Sponsorships
IBD Horizons                       $25,000.00   Corporate Sponsorships
IBD Remedy Inc.                     $5,000.00   Fellowships and
                                                 Scholarships
IBD Remedy Inc.                    $20,000.00   Patient Support
Illinois Cancercare                 $3,000.00   Corporate Sponsorships
 Foundation
Illinois Society of                $40,000.00   Corporate Sponsorships
 Dermatology Physician
 Assistants
Illinois Society of                $20,000.00   Corporate Sponsorships
 Dermatology Physician
 Assistants
Imedex LLC                        $200,000.00   Educational Grants
Imedex LLC                         $10,000.00   Educational Grants
Imedex LLC                         $10,000.00   Educational Grants
Imedex LLC                         $50,000.00   Educational Grants
Imedex LLC                         $50,000.00   Educational Grants
Imedex LLC                         $50,000.00   Educational Grants
Imedex LLC                        ($3,596.00)   Educational Grants
Imedex LLC                          ($247.00)   Educational Grants
Imedex LLC                        $114,000.00   Corporate Sponsorships
Imedex LLC                         $45,750.00   Corporate Sponsorships
Impact Education LLC               $75,000.00   Educational Grants
Indian Doc Associate of             $2,500.00   Corporate Sponsorships
 Houston
Indiana Parkinson                   $2,500.00   Corporate Sponsorships
 Foundation
Indiana Parkinson                   $2,500.00   Corporate Sponsorships
 Foundation
Indiana Univ                       $65,000.00   Educational Grants
Indiana Univ                       $10,000.00   Charitable Donations
Indiana Urological                  $5,000.00   Corporate Sponsorships
 Association
Infectious Diseases Society        $10,000.00   Educational Grants
 of America
Inflammatory Bowel Disease         $50,000.00   Educational Grants
 Support Foundation
Innovation Foundation Inc.         $55,000.00   Corporate Sponsorships
Integra Life Science              $500,000.00   Educational Grants
 Service
Integrated Benefits                $25,000.00   Corporate Sponsorships
 Institute Inc.
Integrated Med Foundation          $15,000.00   Charitable Donations
Integrated Med Foundation           $5,000.00   Corporate Sponsorships
Integrated Med Foundation           $4,500.00   Corporate Sponsorships
International Aids Society--       $50,000.00   Educational Grants
 Usa
International Aids Society--       $75,000.00   Educational Grants
 Usa
International Alliance for          $5,000.00   Educational Grants
 Biological Standardization
International Association          $25,000.00   Corporate Sponsorships
 for The Study of Lung
 Cancer
International Association          $95,150.00   Corporate Sponsorships
 for The Study of Lung
 Cancer
International Association         $264,000.00   Corporate Sponsorships
 for The Study of Lung
 Cancer
International Association          $75,000.00   Corporate Sponsorships
 for The Study of Lung
 Cancer
International Association          $75,000.00   Corporate Sponsorships
 for The Study of Lung
 Cancer
International Cancer               $10,000.00   Corporate Sponsorships
 Advocacy Netwk
International Chinese              $10,000.00   Corporate Sponsorships
 Statistical Associate
International Dermatology          $70,000.00   Corporate Sponsorships
 Outcome Measures
International Dermatology         $150,000.00   Corporate Sponsorships
 Outcome Measures
International League of            $20,000.00   Charitable Donations
 Associate for Rheumlgy
International Medical Corps         $5,000.00   Charitable Donations
International Pelvic Pain          $21,000.00   Corporate Sponsorships
 Society
International Physician            $90,000.00   Corporate Sponsorships
 Ntwrk Dba International
 Oncology Ntwrk
International Physician            $50,000.00   Corporate Sponsorships
 Ntwrk Dba International
 Oncology Ntwrk
International Physician            $75,000.00   Corporate Sponsorships
 Ntwrk Dba International
 Oncology Ntwrk
International Society for           $5,000.00   Educational Grants
 Antiviral Research
International Society for           $3,000.00   Educational Grants
 The Study of Xenobiotics
International Society of           $86,420.00   Corporate Sponsorships
 Nephrology
Iraq And Afghanistan               $15,000.00   Corporate Sponsorships
 Veterans
Jefferson Med College at           $10,000.00   Educational Grants
 Thomas Jefferson Univ
Jefferson Med College at            $3,000.00   Corporate Sponsorships
 Thomas Jefferson Univ
Jefferson Med College at            $5,000.00   Educational Grants
 Thomas Jefferson Univ
Jewish Hospital                     $7,500.00   Corporate Sponsorships
Johns Hopkins Technology           $40,000.00   Fellowships and
 Ventures                                        Scholarships
Johns Hopkins Technology           $40,000.00   Fellowships and
 Ventures                                        Scholarships
Johns Hopkins Technology           $40,000.00   Fellowships and
 Ventures                                        Scholarships
Johns Hopkins Technology            $1,500.00   Corporate Sponsorships
 Ventures
Johns Hopkins Technology            $6,500.00   Fellowships and
 Ventures                                        Scholarships
Johns Hopkins Univ School          $25,000.00   Corporate Sponsorships
 of Medicine
Johns Hopkins Univ School          $20,000.00   Educational Grants
 of Medicine
Jonathan Wood and Associate        $10,000.00   Corporate Sponsorships
JWC Covenant Inc.                  $50,000.00   Educational Grants
Kansas Univ Endowment               $1,000.00   Charitable Donations
 Association
Keystone Symposia                  $25,000.00   Corporate Sponsorships
Keystone Symposia                  $25,000.00   Corporate Sponsorships
Kidney Foundation Inc..             $5,000.00   Corporate Sponsorships
 Northeast
Laboratorio Clinico Toledo            $735.00   Patient Support
Laboratorio Clinico Toledo          $1,185.00   Patient Support
Laboratorio Clinico Toledo          $1,500.00   Patient Support
Laboratorio Clinico Toledo            $450.00   Patient Support
Laboratorio Clinico Toledo            $750.00   Patient Support
Laboratorio Clinico Toledo            $270.00   Patient Support
Laboratorio Clinico Toledo          $1,545.00   Patient Support
Laboratorio Clinico Toledo            $552.00   Patient Support
Laboratorio Clinico Toledo            $375.00   Patient Support
Laboratorio Clinico Toledo            $375.00   Patient Support
Laboratorio Clinico Toledo            $675.00   Patient Support
Laboratorio Clinico Toledo          $1,095.00   Patient Support
Laboratorio Clinico Toledo          $2,085.00   Patient Support
Laboratorio Clinico Toledo          $6,000.00   Patient Support
Laboratorio Clinico Toledo            $375.00   Patient Support
Laboratorio Clinico Toledo            $375.00   Patient Support
Laboratorio Clinico Toledo            $705.00   Patient Support
Laboratorio Clinico Toledo          $2,250.00   Patient Support
Laboratorio Clinico Toledo            $375.00   Patient Support
Laboratorio Clinico Toledo            $375.00   Patient Support
Laboratorio Clinico Toledo            $390.00   Patient Support
Laboratorio Clinico Toledo            $525.00   Patient Support
Laboratorio Clinico Toledo            $750.00   Patient Support
Laboratorio Clinico Toledo          $1,035.00   Patient Support
Laboratorio Clinico Toledo          $1,125.00   Patient Support
Laboratorio Clinico Toledo          $1,185.00   Patient Support
Laboratorio Clinico Toledo          $1,500.00   Patient Support
Laboratorio Clinico Toledo          $1,515.00   Patient Support
Laboratorio Clinico Toledo            $750.00   Patient Support
Laboratorio Clinico Toledo          $1,500.00   Patient Support
Laboratorio Clinico Toledo          $1,950.00   Patient Support
Laboratorio Clinico Toledo            $735.00   Patient Support
Laboratorio Clinico Toledo            $735.00   Patient Support
Laboratorio Clinico Toledo            $555.00   Patient Support
Laboratorio Clinico Toledo          $1,125.00   Patient Support
Laboratorio Clinico Toledo            $375.00   Patient Support
Laboratorio Clinico Toledo            $750.00   Patient Support
Laboratorio Clinico Toledo            $855.00   Patient Support
Laboratorio Clinico Toledo          $1,020.00   Patient Support
Laboratorio Clinico Toledo          $1,125.00   Patient Support
Laboratorio Clinico Toledo            $375.00   Patient Support
Laboratorio Clinico Toledo            $375.00   Patient Support
Laboratorio Clinico Toledo            $990.00   Patient Support
Laboratorio Clinico Toledo          $1,125.00   Patient Support
Laboratorio Clinico Toledo          $1,500.00   Patient Support
Laboratorio Clinico Toledo          $3,000.00   Patient Support
Laboratorio Clinico Toledo            $360.00   Patient Support
Laboratorio Clinico Toledo            $375.00   Patient Support
Laboratorio Clinico Toledo            $510.00   Patient Support
Laboratorio Clinico Toledo            $600.00   Patient Support
Laboratorio Clinico Toledo            $750.00   Patient Support
Laboratorio Clinico Toledo          $2,595.00   Patient Support
Laboratorio Clinico Toledo            $750.00   Patient Support
Laboratorio Clinico Toledo            $375.00   Patient Support
Laboratorio Clinico Toledo            $450.00   Patient Support
Laboratorio Clinico Toledo            $825.00   Patient Support
Laboratorio Clinico Toledo          $1,035.00   Patient Support
Laboratorio Clinico Toledo          $1,500.00   Patient Support
Laboratorio Clinico Toledo          $1,860.00   Patient Support
Laboratorio Clinico Toledo          $1,080.00   Patient Support
Laboratorio Clinico Toledo          $1,500.00   Patient Support
Laboratorio Clinico Toledo            $750.00   Patient Support
Laboratorio Clinico Toledo            $750.00   Patient Support
Laboratorio Clinico Toledo          $1,005.00   Patient Support
Laboratorio Clinico Toledo          $1,125.00   Patient Support
Laboratorio Clinico Toledo          $1,500.00   Patient Support
Laboratorio Clinico Toledo            $750.00   Patient Support
Laboratorio Clinico Toledo          $1,500.00   Patient Support
Laboratorio Clinico Toledo          $1,500.00   Patient Support
Laboratorio Clinico Toledo          $1,500.00   Patient Support
Laboratorio Clinico Toledo            $900.00   Patient Support
Laboratorio Clinico Toledo          $1,290.00   Patient Support
Laboratorio Clinico Toledo            $450.00   Patient Support
Laboratorio Clinico Toledo            $525.00   Patient Support
Laboratorio Clinico Toledo            $600.00   Patient Support
Laboratorio Clinico Toledo            $750.00   Patient Support
Laboratorio Clinico Toledo          $1,050.00   Patient Support
Laboratorio Clinico Toledo          $1,380.00   Patient Support
Laboratorio Clinico Toledo            $750.00   Patient Support
Laboratorio Clinico Toledo            $750.00   Patient Support
Laboratorio Clinico Toledo            $690.00   Patient Support
Laboratorio Clinico Toledo            $720.00   Patient Support
Laboratorio Clinico Toledo            $739.00   Patient Support
Laboratorio Clinico Toledo            $750.00   Patient Support
Laboratorio Clinico Toledo            $885.00   Patient Support
Laboratorio Clinico Toledo          $1,035.00   Patient Support
Laboratorio Clinico Toledo          $3,000.00   Patient Support
Laboratorio Clinico Toledo            $240.00   Patient Support
Laboratorio Clinico Toledo          $2,220.00   Patient Support
Lake County Haven                  $10,000.00   Charitable Donations
Large Urology Group                $25,000.00   Corporate Sponsorships
 Practice Associate
Large Urology Group                $66,400.00   Corporate Sponsorships
 Practice Associate
Large Urology Group                $20,000.00   Corporate Sponsorships
 Practice Associate
Latino Center On Aging              $5,000.00   Corporate Sponsorships
Lenox Hill Hospital                $10,000.00   Educational Grants
Leukemia and Lymphoma           $1,267,000.00   Charitable Donations
 Society
Leukemia and Lymphoma              $50,000.00   Educational Grants
 Society
Leukemia and Lymphoma               $5,000.00   Corporate Sponsorships
 Society
Leukemia and Lymphoma              $25,000.00   Educational Grants
 Society
Leukemia and Lymphoma              $15,000.00   Corporate Sponsorships
 Society
Leukemia and Lymphoma              $50,000.00   Educational Grants
 Society
Leukemia and Lymphoma               $2,500.00   Corporate Sponsorships
 Society
Leukemia and Lymphoma              $75,000.00   Educational Grants
 Society
Leukemia and Lymphoma              $32,500.00   Corporate Sponsorships
 Society
Leukemia and Lymphoma              $50,000.00   Educational Grants
 Society
Leukemia and Lymphoma              $30,000.00   Corporate Sponsorships
 Society
Leukemia and Lymphoma             $100,000.00   Corporate Sponsorships
 Society
Leukemia and Lymphoma              $10,000.00   Corporate Sponsorships
 Society
Leukemia Research                  $50,000.00   Fellowships and
 Foundation                                      Scholarships
Leukemia Research                   $5,000.00   Patient Support
 Foundation
Leukemia Research                   $5,000.00   Educational Grants
 Foundation
Leukemia Research                   $3,000.00   Corporate Sponsorships
 Foundation
Liver Health Connection            $75,000.00   Fellowships and
                                                 Scholarships
Liver Health Connection             $5,000.00   Corporate Sponsorships
Livestrong Foundation              $10,000.00   Patient Support
Lone Star Parkinson Society           $500.00   Corporate Sponsorships
Louisiana Urological                $5,000.00   Corporate Sponsorships
 Society
Loyola Stritch School of            $1,000.00   Charitable Donations
 Medicine Division of
 Dermatology
Loyola Stritch School of            $1,000.00   Charitable Donations
 Medicine Division of
 Dermatology
Lung Cancer Alliance               $25,000.00   Corporate Sponsorships
Lung Cancer Alliance              $100,000.00   Corporate Sponsorships
Lung Cancer Alliance               $50,000.00   Corporate Sponsorships
Lung Cancer Alliance               $50,000.00   Corporate Sponsorships
Lung Cancer Research               $50,000.00   Charitable Donations
 Foundation
Lung Cancer Research               $25,000.00   Charitable Donations
 Foundation
Lungevity Foundation               $50,000.00   Educational Grants
Lungevity Foundation                $5,000.00   Corporate Sponsorships
Lungevity Foundation                $2,500.00   Corporate Sponsorships
Lungevity Foundation               $25,000.00   Corporate Sponsorships
Lungevity Foundation               $75,000.00   Corporate Sponsorships
Lupus and Allied Diseases           $6,000.00   Corporate Sponsorships
 Association
Lupus and Allied Diseases          $25,000.00   Corporate Sponsorships
 Association
Lupus and Allied Diseases          $35,000.00   Corporate Sponsorships
 Association
Lupus Foundation New                $5,000.00   Corporate Sponsorships
 England, Inc.
Lupus Foundation of Florida         $5,000.00   Corporate Sponsorships
 Inc.
Lupus Research Alliance,           $15,000.00   Corporate Sponsorships
 Inc.
Lymphoma Research                   $5,000.00   Corporate Sponsorships
 Foundation
Lymphoma Research                  $40,000.00   Corporate Sponsorships
 Foundation
Lymphoma Research                  $10,000.00   Corporate Sponsorships
 Foundation
Lymphoma Research                  $10,000.00   Corporate Sponsorships
 Foundation
MS Cure Fund Inc.                  $15,000.00   Educational Grants
Magellan Rx Management Inc.        $20,000.00   Corporate Sponsorships
March of Dimes Foundation           $5,000.00   Charitable Donations
Massachusetts Association           $4,000.00   Corporate Sponsorships
 for Mental Health
Massachusetts General              $40,000.00   Fellowships and
 Hospital                                        Scholarships
Massachusetts General              $10,000.00   Corporate Sponsorships
 Hospital for Children
Massachusetts General              $85,000.00   Corporate Sponsorships
 Hospital for Children
Massachusetts Prostate              $2,500.00   Educational Grants
 Cancer Coalition
Massachusetts Society for           $7,500.00   Educational Grants
 Med Research
Massachusetts Society of            $5,000.00   Corporate Sponsorships
 Clinical Oncologists
ME Strong Inc.                      $2,500.00   Corporate Sponsorships
Med--LQ LLC                        $50,000.00   Educational Grants
Med College of Wisconsin            $2,000.00   Corporate Sponsorships
Med College of Wisconsin            $1,000.00   Corporate Sponsorships
Med Univ of South Carolina          $5,000.00   Educational Grants
 Foundation
Medical Learning Institute         $33,790.00   Educational Grants
Medical Learning Institute         $75,000.00   Educational Grants
Medical Learning Institute         $42,300.00   Educational Grants
Medical Learning Institute        $116,850.00   Educational Grants
Medical Univ of South              $10,000.00   Educational Grants
 Carolina
Medina Community Clinic             $1,000.00   Corporate Sponsorships
Medscape LLC                       $50,000.00   Educational Grants
Medscape LLC                      $125,000.00   Educational Grants
Medscape LLC                      $175,000.00   Educational Grants
Medscape LLC                      $200,000.00   Educational Grants
Medscape LLC                      $212,000.00   Educational Grants
Medscape LLC                      $235,500.00   Educational Grants
Medscape LLC                      $565,100.00   Educational Grants
Medscape LLC                       $38,000.00   Educational Grants
Medscape LLC                       $52,500.00   Educational Grants
Medscape LLC                      $300,000.00   Educational Grants
Medscape LLC                       $33,500.00   Educational Grants
Memorial Sloan Kettering           $25,000.00   Educational Grants
 Cancer Center
Memphis Business Group On           $5,100.00   Corporate Sponsorships
 Health
Mens Health and Wellness            $1,500.00   Corporate Sponsorships
 Center
Mercy Med Center Inc.               $3,250.00   Corporate Sponsorships
Mercy Med Center Inc.               $3,250.00   Corporate Sponsorships
Methodist Hospital                 $25,000.00   Corporate Sponsorships
Methodist Hospital                  $1,000.00   Corporate Sponsorships
Michael J Fox Foundation            $1,000.00   Corporate Sponsorships
Michael J Fox Foundation           $50,000.00   Corporate Sponsorships
Michigan Institute of               $5,000.00   Corporate Sponsorships
 Urology, PC
Michigan Parkinson                 $10,000.00   Corporate Sponsorships
 Foundation
Michigan Parkinson                  $1,000.00   Corporate Sponsorships
 Foundation
Michigan Rheumatism Society        $25,000.00   Corporate Sponsorships
Mid America MS Achievement          $2,000.00   Corporate Sponsorships
 Center
Midwest Business Group on           $2,500.00   Corporate Sponsorships
 Health
Midwest Business Group on           $2,500.00   Corporate Sponsorships
 Health
Miles for Cystic Fibrosis           $2,500.00   Corporate Sponsorships
Minnesota Urological                $5,000.00   Corporate Sponsorships
 Society
Missouri Hepatitis C               $20,000.00   Educational Grants
 Alliance
Mount Sinai School of              $10,000.00   Educational Grants
 Medicine
Mount Sinai School of              $40,000.00   Fellowships and
 Medicine                                        Scholarships
Mount Sinai School of              $30,000.00   Corporate Sponsorships
 Medicine
Mount Sinai School of              $40,000.00   Educational Grants
 Medicine
Movement Disorder Society           $1,000.00   Corporate Sponsorships
Movement Disorder Society          $20,000.00   Educational Grants
Movement Disorder Society         $321,500.00   Corporate Sponsorships
Movement Disorder Society          $12,000.00   Educational Grants
Movement Disorder Society          $11,000.00   Corporate Sponsorships
MS Views and News Inc.              $5,000.00   Educational Grants
Multiple Myeloma Research          $10,000.00   Educational Grants
 Foundation Inc.
Multiple Myeloma Research          $25,000.00   Educational Grants
 Foundation Inc.
Multiple Myeloma Research          $15,000.00   Educational Grants
 Foundation Inc.
Multiple Myeloma Research          $50,000.00   Fellowships and
 Foundation Inc.                                 Scholarships
Multiple Sclerosis                  $5,000.00   Patient Support
 Foundation Inc.
Musella Foundation for             $25,000.00   Charitable Donations
 Brain Tumor Research and
 Information Inc.
Nashville Cares Inc.                $8,000.00   Corporate Sponsorships
National Academy of                $30,000.00   Corporate Sponsorships
 Dermatology Nurse
 Practitioners
National Aids Treatment           $300,000.00   Patient Support
 Advocacy Project
National Alliance of Mental         $5,000.00   Corporate Sponsorships
 Illness Flordia
National Alliance of Mental         $7,500.00   Corporate Sponsorships
 Illness Tennessee
National Alliance of State         $10,000.00   Corporate Sponsorships
 and Territorial AIDS
 Directors
National Alliance of State         $50,000.00   Charitable Donations
 and Territorial Aids
 Directors
National Animal Interest           $20,000.00   Charitable Donations
 Alliance
National Associate of              $45,000.00   Educational Grants
 Managed Care Physician
National Associate of              $10,500.00   Corporate Sponsorships
 Managed Care Physician
National Associate of              $20,000.00   Educational Grants
 Managed Care Physician
National Associate of              $25,000.00   Educational Grants
 Managed Care Physician
National Associate of              $45,000.00   Educational Grants
 Managed Care Physician
National Associate of              $20,000.00   Educational Grants
 Managed Care Physician
National Associate of              $35,000.00   Educational Grants
 Managed Care Physician
National Associate of              $10,500.00   Corporate Sponsorships
 Managed Care Physician
National Associate of              $10,000.00   Charitable Donations
 Pediatric Nurse
 Practitioners
National Association of             $2,500.00   Corporate Sponsorships
 Hispanic Nurses
National Association of            $25,000.00   Corporate Sponsorships
 Latino Elected and
 Appointed officials
 Education Fund
National Brain Tumor               $50,000.00   Patient Support
 Society (Nbts)
National Brain Tumor               $25,000.00   Corporate Sponsorships
 Society, Inc.
National Breast Cancer              $5,000.00   Patient Support
 Coalition Fund
National Business Coalition         $7,500.00   Corporate Sponsorships
 On Health
National Business Group On         $25,000.00   Corporate Sponsorships
 Health
National Coalition for             $40,000.00   Corporate Sponsorships
 Cancer
National Coalition for              $2,500.00   Corporate Sponsorships
 Cancer
National Commission On             $10,000.00   Educational Grants
 Correctional Health Care
National Committee of             $125,000.00   Corporate Sponsorships
 Quality Assurance
National Community                 $25,000.00   Corporate Sponsorships
 Dispensing Associate NCODA
National Community                 $30,000.00   Corporate Sponsorships
 Dispensing Associate NCODA
National Community                 $35,000.00   Corporate Sponsorships
 Dispensing Associate NCODA
National Comprehensive             $90,898.00   Educational Grants
 Cancer Network
National Comprehensive             $25,000.00   Educational Grants
 Cancer Network
National Comprehensive             $10,000.00   Educational Grants
 Cancer Network
National Comprehensive             $25,000.00   Educational Grants
 Cancer Network
National Comprehensive             $50,000.00   Educational Grants
 Cancer Network
National Comprehensive             $25,000.00   Educational Grants
 Cancer Network
National Comprehensive             $50,000.00   Educational Grants
 Cancer Network
National Comprehensive             $75,000.00   Educational Grants
 Cancer Network
National Comprehensive             $55,000.00   Educational Grants
 Cancer Network
National Comprehensive             $50,000.00   Charitable Donations
 Cancer Network
National Comprehensive             $15,000.00   Educational Grants
 Cancer Network
National Comprehensive             $75,000.00   Educational Grants
 Cancer Network
National Federation of              $5,000.00   Corporate Sponsorships
 Independent
National Foundation for The      ($81,525.67)   Educational Grants
 Centers for Disease
 Control and Prevention
National Hispanic Council          $25,000.00   Corporate Sponsorships
 On Aging
National Kdny Foundation          $292,054.00   Educational Grants
 Inc.
National Medical                    $7,500.00   Educational Grants
 Association
National Minority Quality          $25,000.00   Corporate Sponsorships
 forum
National Multiple Sclerosis        $10,000.00   Corporate Sponsorships
 Society
National Multiple Sclerosis         $2,500.00   Corporate Sponsorships
 Society
National Multiple Sclerosis         $2,000.00   Corporate Sponsorships
 Society
National Multiple Sclerosis        $25,000.00   Corporate Sponsorships
 Society-Greater Illinois
 Chapter
National Organization of            $5,000.00   Corporate Sponsorships
 Rheumatology Managers
National Pancreas                  $80,000.00   Charitable Donations
 Foundation
National Pancreas                  $80,000.00   Charitable Donations
 Foundation
National Pancreas                  $85,000.00   Educational Grants
 Foundation
National Pancreas                 $190,000.00   Educational Grants
 Foundation
National Pancreas                   $3,500.00   Corporate Sponsorships
 Foundation
National Pancreas                   $1,000.00   Corporate Sponsorships
 Foundation
National Pancreas                  $85,000.00   Charitable Donations
 Foundation
National Pancreas                  $85,000.00   Educational Grants
 Foundation
National Parkinson                  $2,500.00   Corporate Sponsorships
 Foundation Inc.
National Parkinson                  $1,250.00   Corporate Sponsorships
 Foundation Inc.
National Parkinson                 $85,000.00   Corporate Sponsorships
 Foundation Inc.
National Parkinson                 $45,000.00   Educational Grants
 Foundation Inc.
National Parkinson                 $50,000.00   Educational Grants
 Foundation Inc.
National Parkinson                  $5,000.00   Corporate Sponsorships
 Foundation Inc.
National Psoriasis                 $50,000.00   Corporate Sponsorships
 Foundation
National Psoriasis                 $25,000.00   Corporate Sponsorships
 Foundation
National Psoriasis                 $35,000.00   Corporate Sponsorships
 Foundation
National Psoriasis                 $50,000.00   Corporate Sponsorships
 Foundation
National Psoriasis                 $35,000.00   Corporate Sponsorships
 Foundation
National Psoriasis                 $15,000.00   Corporate Sponsorships
 Foundation
National Psoriasis                 $10,000.00   Educational Grants
 Foundation
National Psoriasis                 $75,000.00   Corporate Sponsorships
 Foundation
National Psoriasis                 $25,000.00   Educational Grants
 Foundation
National Psoriasis                 $15,000.00   Corporate Sponsorships
 Foundation
National Psoriasis                 $10,000.00   Educational Grants
 Foundation
National Psoriasis                 $15,000.00   Educational Grants
 Foundation
National Psoriasis                 $50,000.00   Educational Grants
 Foundation
National Psoriasis                 $35,000.00   Educational Grants
 Foundation
National Psoriasis                  $5,000.00   Corporate Sponsorships
 Foundation
National Psoriasis                 $50,000.00   Educational Grants
 Foundation
National Psoriasis                 $25,000.00   Corporate Sponsorships
 Foundation
National Psoriasis                $100,000.00   Corporate Sponsorships
 Foundation
National Psoriasis                $150,000.00   Corporate Sponsorships
 Foundation
National Psoriasis                 $20,000.00   Corporate Sponsorships
 Foundation
National Psoriasis                 $30,000.00   Corporate Sponsorships
 Foundation
National Psoriasis                 $30,000.00   Corporate Sponsorships
 Foundation
National Psoriasis                 $30,000.00   Corporate Sponsorships
 Foundation
National Psoriasis                 $35,000.00   Corporate Sponsorships
 Foundation
National Psoriasis                 $40,000.00   Corporate Sponsorships
 Foundation
National Society for               $50,000.00   Corporate Sponsorships
 Cutaneous Medicine
National Society for              $140,000.00   Corporate Sponsorships
 Cutaneous Medicine
National Society for              $150,000.00   Corporate Sponsorships
 Cutaneous Medicine
Neuro Challenge Foundation         $25,000.00   Corporate Sponsorships
 Inc.
Neurologic Disease                  $4,995.00   Educational Grants
 Foundation
New England Dermatological         $75,000.00   Corporate Sponsorships
 Society
New England Immunology              $2,000.00   Corporate Sponsorships
 Conference Inc.
New England Quality Care            $5,000.00   Corporate Sponsorships
 Alliance
New Venture Fund                   $10,000.00   Educational Grants
New York Academy of Science         $2,500.00   Educational Grants
New York Academy of Science         $5,000.00   Corporate Sponsorships
New York Med Colllege              $50,000.00   Educational Grants
 office of Continuing Med
 Education
New York Society for               $55,000.00   Corporate Sponsorships
 Gastrointestinal Endoscopy
New York State Rheumlgy            $18,000.00   Corporate Sponsorships
 Society
New York State Rheumlgy            $22,500.00   Corporate Sponsorships
 Society
Nexus Global Group Science          $5,000.00   Corporate Sponsorships
Nicole T. Jarvis, M.D.,             $2,500.00   Corporate Sponsorships
 PLLC
NL Communications Inc.             $50,000.00   Educational Grants
NL Communications Inc.             $35,000.00   Educational Grants
NL Communications Inc.             $35,000.00   Educational Grants
NL Communications Inc.             $35,000.00   Educational Grants
NL Communications Inc.             $40,000.00   Educational Grants
NL Communications Inc.             $20,000.00   Educational Grants
NL Communications Inc.             $40,000.00   Educational Grants
NL Communications Inc.             $20,000.00   Educational Grants
NL Communications Inc.             $65,000.00   Educational Grants
NL Communications Inc.             $75,000.00   Educational Grants
NL Communications Inc.             $50,000.00   Educational Grants
NL Communications Inc.             $30,000.00   Educational Grants
NL Communications Inc.             $75,000.00   Educational Grants
North American Center for         $375,025.00   Educational Grants
 Continuing Med Education
North American Center for          $90,000.00   Educational Grants
 Continuing Med Education
North American Society for         $15,000.00   Educational Grants
 Pediatric Gastroenterology
 Hepatology and Nutrition
North Carolina Biosciences          $2,000.00   Corporate Sponsorships
 Organization
North Dakota Pharmacists            $2,500.00   Corporate Sponsorships
 Association
Northeast Business Group On        $15,000.00   Corporate Sponsorships
 Health
Northeast Business Group On        $15,000.00   Corporate Sponsorships
 Health
Northeastern University             $1,000.00   Charitable Donations
Northern Illinois                   $1,000.00   Charitable Donations
 University Foundation
Northwest Health Law                $1,000.00   Corporate Sponsorships
 Advocates
Northwest Indiana                   $1,000.00   Corporate Sponsorships
 Parkinsons
Northwest Kidney Centers            $2,500.00   Corporate Sponsorships
Northwest Parkinsons                $5,000.00   Educational Grants
 Foundation
Northwest Parkinsons               $14,900.00   Corporate Sponsorships
 Foundation
Northwestern Univ                  $25,000.00   Corporate Sponsorships
Northwestern Univ                  $50,000.00   Fellowships and
                                                 Scholarships
Norton Healthcare                   $3,000.00   Corporate Sponsorships
 Foundation
Norwich University                  $1,000.00   Charitable Donations
NYU School of Medicine              $5,000.00   Educational Grants
NYU School of Medicine             $10,000.00   Educational Grants
NYU School of Medicine              $7,500.00   Educational Grants
NYU School of Medicine             $10,000.00   Educational Grants
NYU School of Medicine             $20,000.00   Educational Grants
Ocular Immunology and               $5,000.00   Corporate Sponsorships
 Uveitis Foundation
Ocular Immunology and              $15,000.00   Corporate Sponsorships
 Uveitis Foundation
Ohio Association of                $10,000.00   Corporate Sponsorships
 Rheumatology
Ohio Gastroenterology               $1,250.00   Corporate Sponsorships
 Society
Ohio Gastroenterology               $1,250.00   Corporate Sponsorships
 Society
Ohio Gastroenterology               $2,500.00   Corporate Sponsorships
 Society
Omnia Education Inc.               $98,000.00   Educational Grants
Omnia Education Inc.              $350,000.00   Educational Grants
Oncology Nursing Society           $20,200.00   Corporate Sponsorships
Oradian Inc.                       $75,000.00   Corporate Sponsorships
Oregon Health and Science           $3,500.00   Corporate Sponsorships
 Univ
Oregon Health and Science          $20,000.00   Educational Grants
 Univ
Oregon Health and Science           $5,000.00   Educational Grants
 Univ
Oregon Health and Science           $3,000.00   Educational Grants
 Univ
Oregon Health and Science          $20,000.00   Educational Grants
 Univ
Osmania Gandhi Kakatiya             $2,500.00   Corporate Sponsorships
 Medical Alumni Association
 of America
Pacific Dermatologic               $20,000.00   Corporate Sponsorships
 Association
Pacific Dermatologic               $20,000.00   Corporate Sponsorships
 Association
Pack Center LLC                    $22,575.00   Educational Grants
Pack Center LLC                   $175,000.00   Educational Grants
Pack Health LLC                   $119,750.00   Educational Grants
Pack Health LLC                    $80,000.00   Educational Grants
Pack Health LLC                    $79,750.00   Educational Grants
Pack Health LLC                    $50,000.00   Educational Grants
Pack Health LLC                    $42,875.00   Educational Grants
Pack Health LLC                    $42,875.00   Educational Grants
Pack Center LLC                   $100,000.00   Educational Grants
Pancreas Club                      $10,000.00   Educational Grants
Pancreatic Cancer Action           $50,000.00   Educational Grants
 Network
Pancreatic Cancer Action          $282,000.00   Corporate Sponsorships
 Network
Park Nicollet Foundation            $1,000.00   Corporate Sponsorships
Parkinson and Movement             $20,000.00   Educational Grants
 Disorder Alliance
Parkinson and Movement              $4,000.00   Corporate Sponsorships
 Disorder Alliance
Parkinson and Movement              $2,500.00   Corporate Sponsorships
 Disorder Alliance
Parkinson Association               $1,000.00   Corporate Sponsorships
Parkinson Association               $5,000.00   Corporate Sponsorships
Parkinson Council                  $25,000.00   Corporate Sponsorships
Parkinson Foundation                $2,500.00   Corporate Sponsorships
Parkinson Foundation                $5,000.00   Corporate Sponsorships
Parkinson Foundation               $10,000.00   Educational Grants
Parkinson Foundation                $2,500.00   Corporate Sponsorships
Parkinson Study Group              $20,000.00   Educational Grants
Parkinson Study Group              $15,000.00   Corporate Sponsorships
Parkinson Study Group               $2,716.00   Fellowships and
                                                 Scholarships
Parkinson Support Center of         $5,000.00   Corporate Sponsorships
 Kentuciana
Parkinson Support Center of         $5,000.00   Corporate Sponsorships
 Kentuciana
Parkinsons and Movement             $1,500.00   Corporate Sponsorships
 Disorder Foundation
Parkinsons Association              $1,000.00   Corporate Sponsorships
Parkinsons Association              $8,000.00   Educational Grants
Parkinsons Association              $8,000.00   Educational Grants
Parkinson's Awareness               $1,500.00   Corporate Sponsorships
 Association of Central
 Indiana
Parkinsons Disease                  $5,000.00   Corporate Sponsorships
 Foundation
Parkinsons Disease                 $10,000.00   Corporate Sponsorships
 Foundation
Parkinsons Institute                $5,000.00   Corporate Sponsorships
Parkinson's Nebraska                $1,000.00   Corporate Sponsorships
Parkinsons Outreach                 $1,000.00   Corporate Sponsorships
 Association
Partnership for Quality Med         $2,000.00   Charitable Donations
 Donations Pqmd
Patient Access Network            $287,000.00   Charitable Donations
 Foundation
Patient Access Network          $2,284,000.00   Charitable Donations
 Foundation
Patient Access Network         $10,000,000.00   Charitable Donations
 Foundation
Patient Access Network          $7,577,000.00   Charitable Donations
 Foundation
Patient Access Network         $15,000,000.00   Charitable Donations
 Foundation
Patient Empowerment Ntwrk          $40,000.00   Educational Grants
Patient Empowerment Ntwrk          $25,000.00   Educational Grants
Patient Empowerment Ntwrk          $30,000.00   Educational Grants
Patient Empowerment Ntwrk          $30,000.00   Educational Grants
Patient Empowerment Ntwrk          $30,000.00   Educational Grants
Patient Empowerment Ntwrk          $20,000.00   Educational Grants
Patient Empowerment Ntwrk          $15,000.00   Educational Grants
Patient Empowerment Ntwrk          $20,000.00   Educational Grants
Patient Empowerment Ntwrk          $35,000.00   Educational Grants
Pcec Prostrate Conditions           $2,500.00   Corporate Sponsorships
 Education Council
Pediatric Endocrine Society         $3,750.00   Corporate Sponsorships
Pediatric Endocrine Society        $50,000.00   Corporate Sponsorships
Pediatric Endocrinology             $2,500.00   Corporate Sponsorships
 Nursing Society
Pediatric Endocrinology            $17,000.00   Corporate Sponsorships
 Nursing Society
Pediatric Ibd Foundation           $10,000.00   Corporate Sponsorships
Peerview Institute for            ($2,000.00)   Educational Grants
 Medical Education
Pennsylvania Academy of            $10,000.00   Corporate Sponsorships
 Dermatology and
 Dermatologic Surgry
Pennsylvania Biotechnology          $3,000.00   Corporate Sponsorships
 Association
Pennsylvania Prostate               $5,000.00   Educational Grants
 Cancer Coalition
Pennsylvania Society of             $5,000.00   Corporate Sponsorships
 Gastroenterology
People To People Health            $20,000.00   Charitable Donations
 Foundation
People To People Health            $20,000.00   Charitable Donations
 Foundation
Performrx                           $5,000.00   Corporate Sponsorships
Pharmaceutical Research and        $20,000.00   Corporate Sponsorships
 Manufacturers of America
Philadelphia Research and           $5,500.00   Educational Grants
 Education Foundation
Phrmct Care Management             $73,000.00   Corporate Sponsorships
 Associate
Phrmct Care Management             $88,000.00   Corporate Sponsorships
 Associate
Phrmct Care Management             $73,000.00   Corporate Sponsorships
 Associate
Physicians Education               $25,000.00   Educational Grants
 Resource LLC
Physicians Education               $75,000.00   Educational Grants
 Resource LLC
Physicians Education               $50,000.00   Educational Grants
 Resource LLC
Physicians Education               $50,000.00   Educational Grants
 Resource LLC
Pink Door Nonprofit                 $2,400.00   Corporate Sponsorships
 Organization
Pins for Parkinsons                   $500.00   Corporate Sponsorships
Pittsburgh Business Group          $13,000.00   Corporate Sponsorships
 On Health
Pittsburgh Business Group          $13,000.00   Corporate Sponsorships
 On Health
Postgraduate Institute for         $59,725.00   Educational Grants
 Medicine
Presbyterian Healthcare             $5,000.00   Corporate Sponsorships
 Foundation
President and Fellows of            $1,500.00   Educational Grants
 Harvard College
Prevent Cancer Foundation          $25,000.00   Charitable Donations
Prevent Cancer Foundation         $100,000.00   Corporate Sponsorships
Prevent Cancer Foundation           $5,000.00   Corporate Sponsorships
Prime Education Inc.              $150,000.00   Educational Grants
Prime Education Inc.              $225,000.00   Educational Grants
Prime Education Inc.              $190,000.00   Educational Grants
Prime Education Inc.              $244,000.00   Educational Grants
Prime Education Inc.              $332,620.00   Educational Grants
Prime Education Inc.              $100,000.00   Educational Grants
Prime Education Inc.              $200,000.00   Educational Grants
Prime Education Inc.              $100,000.00   Educational Grants
Prime Education Inc.              $106,400.00   Educational Grants
Prime Education Inc.              $128,902.00   Educational Grants
Prime Oncology Inc.                $25,000.00   Educational Grants
Prime Oncology Inc.               $155,125.00   Educational Grants
Prime Oncology Inc.                $75,000.00   Educational Grants
Prime Oncology Inc.               $154,150.00   Educational Grants
Primo Education LLC                $50,000.00   Educational Grants
Princeton Univ Trustees            $50,000.00   Educational Grants
Project Inform                     $75,000.00   Charitable Donations
Project Inform, Inc.               $30,000.00   Corporate Sponsorships
Project Spark Foundation            $1,500.00   Corporate Sponsorships
Projects in Knowledge Inc.        $125,000.00   Educational Grants
Projects in Knowledge Inc.         $80,000.00   Educational Grants
Projects in Knowledge Inc.        $150,000.00   Educational Grants
Prostate Cancer Foundation          $4,000.00   Corporate Sponsorships
 Chicago
Prostate Cancer                     $5,000.00   Patient Support
 International
Prostate Cancer Research           $15,000.00   Corporate Sponsorships
 Instutute
Prostate Health Education           $7,500.00   Educational Grants
 Network
Prostate Health Education           $5,000.00   Educational Grants
 Network
Prostaware                          $1,500.00   Corporate Sponsorships
Psoriasis and Psoriatic           $100,000.00   Corporate Sponsorships
 Arthritis Clinics
 Multicenter Advancement
 Network
Psoriasis and Psoriatic           $100,000.00   Corporate Sponsorships
 Arthritis Clinics
 Multicenter Advancement
 Network
Puerto Rico Associate of           $20,000.00   Educational Grants
 Gastroenterology
Puerto Rico Associate of           $40,000.00   Corporate Sponsorships
 Gastroenterology
Puerto Rico Associate of           $10,000.00   Educational Grants
 Gastroenterology
Purdue Univ College of             $50,000.00   Educational Grants
 Pharmacy
Purdue Univ College of            $175,000.00   Educational Grants
 Pharmacy
Recovery Idaho                      $1,000.00   Corporate Sponsorships
Regents of The Univ of             $40,000.00   Fellowships and
 California                                      Scholarships
Regents of The Univ of             $55,000.00   Fellowships and
 California                                      Scholarships
Regents of The Univ of              ($658.85)   Educational Grants
 California
Regents of The Univ of              $5,000.00   Educational Grants
 California
Regents of The Univ of             $10,000.00   Educational Grants
 California
Regents of The Univ of              $5,000.00   Educational Grants
 California
Regents of The Univ of             $20,000.00   Educational Grants
 California
Regents of The Univ of              $5,000.00   Educational Grants
 Michigan
Regents of The Univ of             $20,000.00   Corporate Sponsorships
 Michigan
Regents of the University           $5,000.00   Educational Grants
 of Minnesota
Rehabilitation and                  $2,500.00   Corporate Sponsorships
 Community
Renal Physician Associate          $30,000.00   Corporate Sponsorships
Research Institute at               $7,500.00   Corporate Sponsorships
 Nationwide Childrens
 Hospital
Research Institute for Fox          $5,000.00   Corporate Sponsorships
 Chase Cancer Center
Rheumatology Association of         $7,500.00   Corporate Sponsorships
 Iowa
Rheumatology Association of         $5,000.00   Corporate Sponsorships
 Iowa
Rheumatology Association of         $7,500.00   Corporate Sponsorships
 Iowa
Rheumatology Association of        $10,000.00   Corporate Sponsorships
 Minnesota and The Dakotas
Rheumatology Nurses Society        $75,000.00   Educational Grants
Rheumatology Nurses Society        $20,000.00   Educational Grants
Rheumatology Nurses Society        $46,325.00   Corporate Sponsorships
Rheumatology Nurses Society        $75,000.00   Educational Grants
Rheumatology Nurses Society        $75,000.00   Educational Grants
Rheumatology Nurses Society        $21,250.00   Corporate Sponsorships
Rheumatology Nurses Society        $45,000.00   Corporate Sponsorships
Rheumlgy Alliance of               $25,000.00   Corporate Sponsorships
 Louisiana
Riverside Family Medicine           $2,500.00   Educational Grants
 Residency The
Riverside Medical Clinic           $10,000.00   Educational Grants
 Charitable Foundation
Robert Michael Educational        $150,000.00   Educational Grants
 Institute LLC
Rock Steady Boxing                    $500.00   Corporate Sponsorships
Rocky Mountain MS Center            $5,000.00   Educational Grants
Rocky Mountain MS Center           $10,000.00   Educational Grants
Rocky Mountain MS Center            $5,000.00   Educational Grants
Rocky Mountain MS Center            $5,000.00   Educational Grants
Rocky Mountain MS Center           $10,000.00   Educational Grants
Roger Williams Medical             $40,000.00   Fellowships and
 Center                                          Scholarships
Roger Williams Medical              $5,000.00   Educational Grants
 Center
Rotary Club of Downtown             $1,000.00   Corporate Sponsorships
 Macon
Rush Univ Medical Center            $5,000.00   Educational Grants
Rush Univ Medical Center            $7,500.00   Educational Grants
Rush Univ Medical Center           $75,000.00   Educational Grants
Rush Univ Medical Center            $5,000.00   Charitable Donations
Rush Univ Medical Center           $75,000.00   Educational Grants
Rush Univ Medical Center           $75,000.00   Educational Grants
Rutgers Univ Foundation             $1,000.00   Charitable Donations
Sacramento Gastrointestinal         $1,500.00   Corporate Sponsorships
 Education and Research
Safety Pharmacology Society         $5,000.00   Educational Grants
San Francisco Aids                 $10,000.00   Charitable Donations
 Foundation
San Francisco Public Center        $75,000.00   Charitable Donations
 Foundation
San Francisco Retina                $5,000.00   Educational Grants
 Foundation
San Francisco Retina                $5,000.00   Educational Grants
 Foundation
San Juan Bautista Medical          $40,000.00   Fellowships and
 Center                                          Scholarships
Scott and White Healthcare          $1,000.00   Corporate Sponsorships
 Foundation
Scripps Health                      $5,000.00   Educational Grants
Scripps Health                      $5,000.00   Educational Grants
Scripps Health                     $50,000.00   Educational Grants
Scripps Research Institute          $2,000.00   Educational Grants
Seattle Science Foundation          $2,500.00   Educational Grants
Seattle Science Foundation          $8,500.00   Educational Grants
Seton Family of Hospitals          $40,000.00   Fellowships and
                                                 Scholarships
Sexual Medicine Society of          $5,000.00   Corporate Sponsorships
 North America
 Foundation(Smsna)
Sexual Medicine Society of        $225,000.00   Corporate Sponsorships
 North America
 Foundation(Smsna)
Shanti Project Inc.                $10,000.00   Patient Support
Share                               $5,000.00   Educational Grants
Share                              $10,000.00   Charitable Donations
Sharsheret                         $10,000.00   Educational Grants
Sheknows LLC                      $102,500.00   Corporate Sponsorships
Sheknows LLC                       $57,500.00   Corporate Sponsorships
Sheknows LLC                      $200,000.00   Corporate Sponsorships
Sinai Health System                $10,000.00   Charitable Donations
Sociedad Dermatologica de          $35,000.00   Patient Support
 Puerto Rico
Sociedad PR Endocrinologia         $15,000.00   Corporate Sponsorships
 y Diabetologia
Sociedad Puertorriquena             $2,000.00   Corporate Sponsorships
 Pediatria
Sociedad Puertorriquena             $9,500.00   Corporate Sponsorships
 Pediatria
Sociedad Puertorriquena            $14,000.00   Corporate Sponsorships
 Pediatria
Society for Clinical               $15,000.00   Corporate Sponsorships
 Research Sites Inc.
Society for Clinical Trials         $2,000.00   Corporate Sponsorships
Society for Leukocyte               $2,500.00   Educational Grants
 Biology
Society for Mucosal                 $2,500.00   Educational Grants
 Immunology
Society for Neuro-Oncology         $50,000.00   Educational Grants
Society for Neuro-Oncology         $55,000.00   Corporate Sponsorships
Society for Neuroscience            $2,000.00   Educational Grants
Society for Neuroscience            $5,000.00   Educational Grants
Society for Womens Health          $15,000.00   Corporate Sponsorships
 Research
Society for Womens Health         $150,000.00   Corporate Sponsorships
 Research
Society of Dermatology             $40,000.00   Corporate Sponsorships
 Physician Assistants
Society of Dermatology             $45,000.00   Corporate Sponsorships
 Physician Assistants
Society of Dermatology             $40,000.00   Corporate Sponsorships
 Physician Assistants
Society of Dermatology             $40,000.00   Corporate Sponsorships
 Physician Assistants
Society of Investigative           $30,000.00   Educational Grants
 Dermatology
Society of Nuclear Medicine         $5,000.00   Corporate Sponsorships
 and Molecular Imaging
Socty for Gynecologic              $10,000.00   Corporate Sponsorships
 Investigation
Socty for Immunotherapy of         $50,000.00   Corporate Sponsorships
 Cancer
South Carolina Alliance of          $6,000.00   Corporate Sponsorships
 Health Plans
South Dakota Parkinson              $1,500.00   Corporate Sponsorships
 Foundation
South Texas Association of         $30,000.00   Corporate Sponsorships
 Rheumatologists
South Texas Association of         $40,000.00   Corporate Sponsorships
 Rheumatologists
Spondylitis Association of         $40,000.00   Educational Grants
 America
Spondylitis Association of         $20,000.00   Educational Grants
 America
Spondyloarthritis Research         $70,000.00   Corporate Sponsorships
 and Treatment Network
 Spartan
Stage One Family Theatre            $5,000.00   Corporate Sponsorships
State of Maryland                  $40,000.00   Educational Grants
State of Pennsylvania              $25,065.00   Educational Grants
State of Pennsylvania              $90,000.00   Educational Grants
State of Pennsylvania              $25,000.00   Educational Grants
State of Pennsylvania              $25,000.00   Educational Grants
Summit for Stem Cellular            $2,500.00   Corporate Sponsorships
 Foundation
Surviveit                          $10,000.00   Educational Grants
Susan G Komen Breast Cancer        $10,000.00   Charitable Donations
 Foundation Inc.
Swedish Medical Center              $5,000.00   Educational Grants
 First Hill Campus
Take A Breather Foundation          $5,000.00   Corporate Sponsorships
Take A Breather Foundation         $20,000.00   Corporate Sponsorships
Talem Health Inc.                 $150,000.00   Educational Grants
Tarsus Cardiology Inc. Dba         $35,000.00   Corporate Sponsorships
 South Beach Symposium
Tennessee Disability                $7,500.00   Corporate Sponsorships
 Coalition
Texas Academy of Family             $2,500.00   Corporate Sponsorships
 Physicians
Texas Neuro Society                 $5,000.00   Corporate Sponsorships
Texas Society for                   $2,000.00   Corporate Sponsorships
 Gastroenterology and
 Endoscopy
Texas Society for                   $2,000.00   Corporate Sponsorships
 Gastroenterology and
 Endoscopy
Texas Society for                   $2,000.00   Corporate Sponsorships
 Gastroenterology and
 Endoscopy
Texas Urological Society            $6,000.00   Corporate Sponsorships
Texas Urological Society            $6,000.00   Corporate Sponsorships
Thomas Jefferson University       ($4,242.75)   Educational Grants
Thomas Jefferson University         $5,000.00   Corporate Sponsorships
Transcelerate Biopharma         $1,500,000.00   Corporate Sponsorships
 Inc.
Trustees of Boston Univ D/B/      $200,000.00   Educational Grants
 A
Trustees of Boston Univ D/B/        $1,500.00   Educational Grants
 A
Trustees of Boston Univ D/B/       $10,000.00   Educational Grants
 A
Trustees of Dartmouth               $1,000.00   Charitable Donations
 College--Administration
Trustees of Tufts College           $1,000.00   Charitable Donations
Trustees of Tufts College           $1,000.00   Charitable Donations
Tufts Medical Center               $50,000.00   Fellowships and
                                                 Scholarships
Tufts Medical Center               $10,000.00   Educational Grants
UC Regents Maxillofacial           $10,000.00   Educational Grants
 Prosthetics Clinic
UC Regents Maxillofacial           $40,000.00   Fellowships and
 Prosthetics Clinic                              Scholarships
UC Regents Maxillofacial            $5,000.00   Educational Grants
 Prosthetics Clinic
UC Regents Maxillofacial           $15,000.00   Educational Grants
 Prosthetics Clinic
UCSF Medical Center at             $50,000.00   Educational Grants
 Parnassus
Ultimate Medical Academy          $225,000.00   Educational Grants
 LLC
Ultimate Medical Academy          $175,000.00   Educational Grants
 LLC
Ultimate Medical Academy          $225,000.00   Educational Grants
 LLC
Ultimate Medical Academy          $200,000.00   Educational Grants
 LLC
Ultimate Medical Academy          $213,500.00   Educational Grants
 LLC
Ultimate Medical Academy          $249,250.00   Educational Grants
 LLC
Ultimate Medical Academy          ($5,370.00)   Educational Grants
 LLC
Ultimate Medical Academy          $250,000.00   Educational Grants
 LLC
Ultimate Medical Academy          $149,000.00   Educational Grants
 LLC
Ultimate Medical Academy          $250,000.00   Educational Grants
 LLC
Ultimate Medical Academy          $213,500.00   Educational Grants
 LLC
Ultimate Medical Academy          $115,000.00   Educational Grants
 LLC
Ultimate Medical Academy          $289,810.00   Educational Grants
 LLC
UMA Education Inc. Dba            $375,000.00   Educational Grants
 Global Education Group
UMA Education Inc. Dba            $200,000.00   Educational Grants
 Global Education Group
UMA Education Inc. Dba             $38,800.00   Educational Grants
 Global Education Group
UMA Education Inc. Dba             $80,000.00   Educational Grants
 Global Education Group
UMASS Memorial Foundation           $2,500.00   Corporate Sponsorships
 Inc.
United Rheumatology                $36,000.00   Corporate Sponsorships
United Rheumatology               $205,000.00   Corporate Sponsorships
United States Adult Cystic          $5,000.00   Educational Grants
 Fibrosis Association Inc.
Univ Health Service at              $1,166.00   Corporate Sponsorships
 Stony Point Inc.
Univ Health Service at              $1,167.00   Corporate Sponsorships
 Stony Point Inc.
Univ Health Service at              $1,167.00   Corporate Sponsorships
 Stony Point Inc.
Univ Health Service at              $5,000.00   Educational Grants
 Stony Point Inc.
Univ Health Service at             $20,000.00   Educational Grants
 Stony Point Inc.
Univ Hospital of Brooklyn         ($5,527.00)   Educational Grants
Univ of California                 $30,000.00   Corporate Sponsorships
 Berkeley--Administration
Univ of California,                $55,000.00   Fellowships and
 Riverside Student Health                        Scholarships
 Services
Univ of Chicago                    $10,000.00   Educational Grants
Univ of Chicago                     $5,000.00   Educational Grants
Univ of Chicago                     $5,000.00   Educational Grants
Univ of Chicago                    $65,000.00   Educational Grants
Univ of Chicago                    $80,000.00   Educational Grants
Univ of Chicago                   $140,000.00   Educational Grants
Univ of Chicago                    $20,000.00   Corporate Sponsorships
Univ of Chicago                    $15,000.00   Charitable Donations
Univ of Chicago                    $10,000.00   Educational Grants
Univ of Chicago                    $30,000.00   Educational Grants
Univ of Cincinnati                 $60,000.00   Educational Grants
Univ of Cincinnati                 $75,000.00   Educational Grants
Univ of Cincinnati                $195,000.00   Educational Grants
Univ of Cincinnati                 $80,000.00   Educational Grants
Univ of Cincinnati                $250,000.00   Educational Grants
Univ of Cincinnati                $454,420.00   Educational Grants
Univ of Cincinnati                 $25,000.00   Educational Grants
Univ of Cincinnati                ($1,212.00)   Educational Grants
Univ of Cincinnati                 $60,000.00   Educational Grants
Univ of Cincinnati                 $75,000.00   Educational Grants
Univ of Cincinnati                  $5,000.00   Educational Grants
 Foundation--Sunflower Fund
Univ of Colorado Denver            $25,000.00   Fellowships and
 School of Medicine                              Scholarships
Univ of Colorado Denver             $4,000.00   Educational Grants
 School of Medicine
Univ of Florida Foundation          $5,000.00   Educational Grants
Univ of Florida Foundation            $500.00   Corporate Sponsorships
Univ of Florida Foundation         $55,000.00   Fellowships and
                                                 Scholarships
Univ of Illinios                    $2,000.00   Educational Grants
Univ of Illinois                    $1,000.00   Corporate Sponsorships
Univ of Illinois Foundation         $5,000.00   Corporate Sponsorships
Univ of Illinois Foundation         $5,000.00   Corporate Sponsorships
Univ of Illinois Foundation         $1,000.00   Charitable Donations
Univ of Louisville Research        $60,000.00   Educational Grants
 Foundation
Univ of Louisville Research        $98,000.00   Educational Grants
 Foundation
Univ of Louisville Research        $47,725.00   Educational Grants
 Foundation
Univ of Louisville Research         $1,000.00   Educational Grants
 Foundation
Univ of Maryland Baltimore         $10,000.00   Educational Grants
 Foundation Inc.
Univ of Maryland Baltimore         $10,000.00   Corporate Sponsorships
 Foundation Inc.
Univ of Miami                      $50,000.00   Fellowships and
                                                 Scholarships
Univ of Miami                      $10,000.00   Educational Grants
Univ of Miami Dept of              $10,000.00   Corporate Sponsorships
 Dermatology
Univ of Nebraska Med Center       $150,000.00   Educational Grants
Univ of Nebraska Med Center           $675.00   Corporate Sponsorships
Univ of Nebraska Med Center        $68,900.00   Educational Grants
Univ of Nebraska Med Center        $25,000.00   Educational Grants
Univ of Nebraska Med Center        $25,000.00   Educational Grants
Univ of Nebraska Med Center         $5,000.00   Educational Grants
Univ of Nebraska Med Center         $7,500.00   Educational Grants
Univ of Nebraska Med Center         $5,000.00   Corporate Sponsorships
Univ of New Mexico                  $5,000.00   Corporate Sponsorships
 Foundation
Univ of North Carolina at          $40,000.00   Fellowships and
 Chapel Hill                                     Scholarships
Univ of North Carolina at         ($5,463.46)   Educational Grants
 Chapel Hill
Univ of North Carolina at        ($40,000.00)   Fellowships and
 Chapel Hill                                     Scholarships
Univ of Pittsburgh                  $2,200.00   Educational Grants
Univ of Pittsburgh                 $10,000.00   Educational Grants
Univ of Pittsburgh                 $15,000.00   Educational Grants
Univ of Pittsburgh                  $2,500.00   Corporate Sponsorships
Univ of Pittsburgh                 $15,000.00   Educational Grants
Univ of Rhode Island                $2,500.00   Educational Grants
 Foundation
Univ of South Alabama               $1,500.00   Corporate Sponsorships
 College of Medicine
Univ of South Florida              $25,000.00   Educational Grants
 Health Professions
 Conferencing Corp
Univ of Southern California        $25,000.00   Educational Grants
Univ of Southern California        $50,000.00   Fellowships and
                                                 Scholarships
Univ of Southern California        $78,500.00   Fellowships and
                                                 Scholarships
Univ of Tennessee Obgyn           ($1,758.03)   Educational Grants
 Center
Univ of Tennessee Obgyn             $2,000.00   Corporate Sponsorships
 Center
Univ of Texas Health               $16,032.00   Corporate Sponsorships
 Science Center at San
 Antonio
Univ of Texas Health               $75,000.00   Educational Grants
 Science Center at San
 Antonio
Univ of Texas Health                $3,000.00   Educational Grants
 Science Center at San
 Antonio
Univ of Texas M D Anderson         $10,000.00   Educational Grants
 Cancer Center
Univ of Texas Southwestern         $55,000.00   Fellowships and
 Med Center                                      Scholarships
Univ of Texas Southwestern          $2,000.00   Educational Grants
 Med Center
Univ of Texas Southwestern         $55,000.00   Educational Grants
 Med Center
Univ of The State of New           $50,000.00   Educational Grants
 York Univ at Buffalo
Univ of Toledo                      $2,000.00   Educational Grants
Universidad Central Del             $7,500.00   Educational Grants
 Caribe School of Medicine
Universidad Central Del            $11,205.00   Educational Grants
 Caribe School of Medicine
Universidad Central Del            $12,000.00   Educational Grants
 Caribe School of Medicine
Universidad Central Del            $12,000.00   Educational Grants
 Caribe School of Medicine
Universidad Central Del             ($308.75)   Educational Grants
 Caribe School of Medicine
Universidad Central Del             $7,500.00   Educational Grants
 Caribe School of Medicine
Universidad Central Del            $15,000.00   Educational Grants
 Caribe School of Medicine
Universidad Central Del            $15,000.00   Educational Grants
 Caribe School of Medicine
Universidad Central Del            $24,939.25   Educational Grants
 Caribe School of Medicine
Universidad Central Del            $10,000.00   Educational Grants
 Caribe School of Medicine
Universidad Central Del            $15,000.00   Educational Grants
 Caribe School of Medicine
Universidad Central Del           ($3,795.00)   Educational Grants
 Caribe School of Medicine
Universidad Central Del           ($3,460.75)   Educational Grants
 Caribe School of Medicine
University of Alabama at            ($186.25)   Educational Grants
 Birmingham Hospital
University of Alabama at           $40,000.00   Fellowships and
 Birmingham Hospital                             Scholarships
University of California           $40,000.00   Fellowships and
 Irvine                                          Scholarships
University of California           $40,000.00   Fellowships and
 Irvine                                          Scholarships
University of Colorado              $1,000.00   Charitable Donations
 Foundation
University of Connecticut          $12,000.00   Fellowships and
 Health Science Center                           Scholarships
University of Connecticut          $40,000.00   Fellowships and
 Health Science Center                           Scholarships
University of Connecticut           ($774.73)   Fellowships and
 Health Science Center                           Scholarships
University of Edinburgh Usa         $1,000.00   Charitable Donations
 Development Trust Inc.
University of Illinois--           $82,092.00   Fellowships and
 office of Business and                          Scholarships
 Financial Services
University of Illinois--           $79,559.00   Fellowships and
 office of Business and                          Scholarships
 Financial Services
University of Rochester            $40,000.00   Fellowships and
                                                 Scholarships
University of Sheffield in          $1,000.00   Charitable Donations
 America Inc.
University of Washington           $40,000.00   Fellowships and
 Medical Center                                  Scholarships
University of Washington            ($255.67)   Educational Grants
 Medical Center
Upstage Lung Cancer                 $5,000.00   Charitable Donations
Urology Center of Colorado         $10,000.00   Corporate Sponsorships
 Foundation
US Too International               $25,000.00   Corporate Sponsorships
US Too International                $1,500.00   Corporate Sponsorships
Valley Childrens Hospital           $4,000.00   Educational Grants
 Foundation
Valley Medial Center                $5,000.00   Corporate Sponsorships
 Foundation
Vanderbilt Univ By and              $5,000.00   Corporate Sponsorships
 Through Its Medical Center
Vanderbilt Univ By and             $12,500.00   Fellowships and
 Through Its Medical Center                      Scholarships
Vanderbilt Univ By and              $5,000.00   Educational Grants
 Through Its Medical Center
Vanderbilt Univ By and             $10,000.00   Educational Grants
 Through Its Medical Center
VHA Inc.                           $35,000.00   Corporate Sponsorships
Vindico Med Education              $25,000.00   Educational Grants
Vindico Med Education              $50,000.00   Educational Grants
Vindico Med Education              $95,000.00   Educational Grants
Vindico Med Education              $75,000.00   Educational Grants
Vindico Med Education              $50,000.00   Educational Grants
Virginia Association of             $2,500.00   Corporate Sponsorships
 Health Plans
Virginia Commonwealth Univ          $2,500.00   Corporate Sponsorships
 School of Medicine
Washington and Lee                  $1,000.00   Charitable Donations
 University
Washington Hospital Center         $10,000.00   Educational Grants
 Corp
Washington Rheumatology            $50,000.00   Corporate Sponsorships
 Alliance
Washington Univ in St Louis         $5,000.00   Educational Grants
Washington Univ in St Louis         $1,600.00   Fellowships and
                                                 Scholarships
Washington Univ in St Louis        $40,000.00   Fellowships and
                                                 Scholarships
Webmd Global LLC                    ($500.00)   Educational Grants
Webmd Global LLC                   $75,000.00   Educational Grants
Webmd Global LLC                  $146,500.00   Educational Grants
Webmd Global LLC                  $340,000.00   Educational Grants
Webmd Global LLC                  $100,000.00   Educational Grants
Webmd Global LLC                  $150,000.00   Educational Grants
Webmd Global LLC                  $105,000.00   Educational Grants
Webmd Global LLC                   $90,000.00   Educational Grants
Webmd Global LLC                  $150,000.00   Educational Grants
Webmd Global LLC                  $300,000.00   Educational Grants
Webmd Global LLC                  $600,000.00   Educational Grants
Webmd Global LLC                  $250,000.00   Educational Grants
Western Pennsylvania                $5,000.00   Fellowships and
 Hospital forbes Regional                        Scholarships
 Campus
Western Pennsylvania              ($1,502.07)   Fellowships and
 Hospital forbes Regional                        Scholarships
 Campus
Western States Pharmacy             $3,250.00   Corporate Sponsorships
 Conference for Pharmacy
 Residents Fellowships and
 Preceptors
Wisconsin Chapter of The            $5,000.00   Corporate Sponsorships
 American College of
 Healthcare Executives
Wisconsin Collaborative for         $2,650.00   Corporate Sponsorships
 Healthcare Quality
Wisconsin Dairyland Chapter         $2,000.00   Corporate Sponsorships
 of Healthcare Information
 and Management Systems
 Society (HIMSS)
Wisconsin Rheumatology             $10,000.00   Corporate Sponsorships
 Association
Wj Weiser Association               $5,000.00   Corporate Sponsorships
 Management Inc.
World Parkinson Coalition           $5,000.00   Charitable Donations
 Inc.
Yale Univ                           $5,000.00   Educational Grants
Young Survival Coalition           $25,000.00   Corporate Sponsorships
Zebrafish Disease Models           $10,000.00   Educational Grants
 Society
Zero The Project To End           $270,000.00   Corporate Sponsorships
 Prostate Cancer
Zero The Project To End            $12,000.00   Corporate Sponsorships
 Prostate Cancer
------------------------------------------------------------------------


                    Grants and Donations Report--2018
    (Parentheses represent refunds of previously disclosed payments)
                         Report as of 3/31/3019
------------------------------------------------------------------------
         Recipient             Payment Amount            Purpose
------------------------------------------------------------------------
50 Hoops                           $25,000.00   Educational Grants
50 Hoops                           $10,000.00   Patient Support
A and R Educational Group          $80,350.00   Corporate Sponsorships
 LLC
A and R Educational Group           $4,500.00   Corporate Sponsorships
 LLC
AAPS                               $50,000.00   Corporate Sponsorships
Aasld Foundation (American        $500,000.00   Charitable Donations
 Association for The Study
 of Liver Disease)
Aasld Foundation (American        $250,000.00   Charitable Donations
 Association for The Study
 of Liver Disease)
Academia Puertorriquena DE          $4,500.00   Corporate Sponsorships
 Neurologia
Academic Cme LLC                   $45,000.00   Educational Grants
Academy of Managed Care            $40,000.00   Corporate Sponsorships
 Pharmacy
Academy of Managed Care            $27,000.00   Corporate Sponsorships
 Pharmacy
Academy of Managed Care            $32,000.00   Corporate Sponsorships
 Pharmacy
Academy of Managed Care            $30,000.00   Corporate Sponsorships
 Pharmacy
Advanced Medical Education          $2,500.00   Corporate Sponsorships
 Consultants, Corp.
Advanced Urology Institute         $10,000.00   Corporate Sponsorships
 Education and General Fund
Advances in Cosmetic and           $75,000.00   Corporate Sponsorships
 Med Dermatology Inc.
Advances in Cosmetic and           $75,000.00   Corporate Sponsorships
 Med Dermatology Inc.
Advances in Cosmetic and           $75,000.00   Corporate Sponsorships
 Med Dermatology Inc.
Adventist Health System--          $15,000.00   Corporate Sponsorships
 Sunbelt Inc.
Aesthetic Dermatology               $7,500.00   Corporate Sponsorships
 Symposia
AIDS Connecticut                    $5,000.00   Corporate Sponsorships
AIDS Foundation of Chicago         $10,000.00   Corporate Sponsorships
AIDS Foundation of Chicago         $10,000.00   Charitable Donations
AIDS Institute                     $10,000.00   Corporate Sponsorships
AIDS Institute                      $7,500.00   Corporate Sponsorships
AIDS Support Network                $2,000.00   Corporate Sponsorships
Aimed Alliance                     $20,000.00   Corporate Sponsorships
Alabama Academy of                  $1,200.00   Corporate Sponsorships
 Neurology
Alabama Associate of Center         $5,000.00   Corporate Sponsorships
 Plans
Alabama Dermatology Society        $50,000.00   Corporate Sponsorships
Alabama Society of                    $750.00   Corporate Sponsorships
 Dermatology Professionals
Albert Einstein College of         $10,000.00   Educational Grants
 Medicine Division of
 Dermatology
Albert Einstein College of         $50,000.00   Educational Grants
 Medicine of Yeshiva Univ
Albert Einstein College of         $45,000.00   Educational Grants
 Medicine of Yeshiva Univ
Alliance for Aging Research         $5,000.00   Corporate Sponsorships
Alsac St Jude Childrens            $15,000.00   Charitable Donations
 Research Hospital
Alzheimers Association              $2,500.00   Corporate Sponsorships
 Greater Illinois Chapter
Alzheimers Disease and            $100,000.00   Corporate Sponsorships
 Related Disorders
 Association Inc.
Alzheimers Disease and             $10,000.00   Charitable Donations
 Related Disorders
 Association Inc.
American Academy of                $40,000.00   Educational Grants
 Dermatology
American Academy of                $10,000.00   Charitable Donations
 Dermatology
American Academy of                 $7,500.00   Corporate Sponsorships
 Dermatology
American Academy of               $300,000.00   Corporate Sponsorships
 Dermatology
American Academy of                $50,000.00   Charitable Donations
 Dermatology
American Academy of                $50,000.00   Educational Grants
 Dermatology
American Academy of Family         $19,000.00   Educational Grants
 Physicians
American Academy of                $30,000.00   Educational Grants
 Neurology Institute
American Academy of                $40,050.00   Corporate Sponsorships
 Neurology Institute
American Academy of                $38,220.00   Corporate Sponsorships
 Neurology Institute
American Academy of               $100,000.00   Fellowships and
 Neurology Institute                             Scholarships
American Academy of                $16,470.00   Corporate Sponsorships
 Neurology Institute
American Academy of                $24,112.40   Corporate Sponsorships
 Ophthalmology Aao
American Academy of                $15,000.00   Corporate Sponsorships
 Pediatrics
American Academy of                $14,000.00   Corporate Sponsorships
 Pediatrics
American Academy of                $95,000.00   Educational Grants
 Physician Assistants
American Association of             $5,000.00   Educational Grants
 Clinical Endocrinologists
 New Jersey Chapter
American Association of            $18,000.00   Educational Grants
 Clinical Endocrinologists
 New Jersey Chapter
American Association for            $5,000.00   Educational Grants
 Accreditation of
 Laboratory Animal Care
 International (Aaalac
 International
American Association for           $40,000.00   Fellowships and
 Cancer Research                                 Scholarships
American Association for           $25,000.00   Patient Support
 Cancer Research
American Association for           $25,000.00   Educational Grants
 Cancer Research
American Association for           $10,000.00   Educational Grants
 Cancer Research
American Association for           $25,000.00   Charitable Donations
 Cancer Research
American Association for           $10,000.00   Educational Grants
 Cancer Research
American Association for           $20,000.00   Educational Grants
 Cancer Research
American Association for            $5,000.00   Educational Grants
 Cancer Research
American Association for           $10,000.00   Educational Grants
 Cancer Research
American Association for            $5,000.00   Educational Grants
 Cancer Research
American Association for            $5,000.00   Educational Grants
 Cancer Research
American Association for           $25,000.00   Educational Grants
 Cancer Research
American Association for           $25,000.00   Educational Grants
 Cancer Research
American Association for           $75,000.00   Educational Grants
 Cancer Research
American Association for           $20,000.00   Charitable Donations
 Laboratory Animal Science
American Association for           $10,000.00   Charitable Donations
 The Study of Liver Disease
American Association of           $200,000.00   Patient Support
 Clinical Endocrinologists
 Inc.
American Association of            $15,200.00   Corporate Sponsorships
 Gynecologic Laparoscopists
 Inc.
American Association of            $50,000.00   Educational Grants
 Nurse Practitioners
American Brain Tumor               $50,000.00   Fellowships and
 Association                                     Scholarships
American Brain Tumor                $2,500.00   Charitable Donations
 Association
American Brain Tumor               $10,000.00   Patient Support
 Association
American Brain Tumor               $10,000.00   Corporate Sponsorships
 Association
American Brain Tumor               $60,000.00   Corporate Sponsorships
 Association
American Brain Tumor                $3,400.00   Corporate Sponsorships
 Association
American Brain Tumor               $10,000.00   Patient Support
 Association
American Brain Tumor               $10,000.00   Patient Support
 Association
American Brain Tumor                $5,000.00   Corporate Sponsorships
 Association
American Brain Tumor               $50,000.00   Fellowships and
 Association                                     Scholarships
American Brain Tumor               $22,500.00   Corporate Sponsorships
 Association
American Brain Tumor               $25,000.00   Corporate Sponsorships
 Association
American Brain Tumor               $50,000.00   Corporate Sponsorships
 Association
American Cancer Society             $5,000.00   Corporate Sponsorships
American Cancer Society             $1,500.00   Corporate Sponsorships
American Cancer Society            $10,000.00   Corporate Sponsorships
American Cancer Society            $10,000.00   Charitable Donations
American Cancer Society             $2,500.00   Corporate Sponsorships
American Cancer Society            $10,000.00   Corporate Sponsorships
American Cancer Society             $5,000.00   Corporate Sponsorships
American Cancer Society             $2,500.00   Corporate Sponsorships
American Cancer Society             $5,000.00   Corporate Sponsorships
American Cancer Society            $10,000.00   Corporate Sponsorships
American Cancer Society             $5,000.00   Corporate Sponsorships
American Cancer Society             $5,000.00   Corporate Sponsorships
American Cancer Society             $2,500.00   Corporate Sponsorships
American Cancer Society             $2,500.00   Corporate Sponsorships
American Cancer Society             $2,500.00   Corporate Sponsorships
American Cancer Society             $2,500.00   Corporate Sponsorships
American Cancer Society             $2,500.00   Corporate Sponsorships
American Cancer Society             $2,500.00   Corporate Sponsorships
American Cancer Society             $5,000.00   Corporate Sponsorships
American Cancer Society            $12,000.00   Corporate Sponsorships
American Cancer Society             $3,500.00   Corporate Sponsorships
American Cancer Society            $10,000.00   Corporate Sponsorships
American Cancer Society            $50,000.00   Corporate Sponsorships
American Cancer Society            $50,000.00   Corporate Sponsorships
American Chemist Society            $3,000.00   Educational Grants
American Chemist Society            $2,500.00   Educational Grants
American Chemist Society            $1,500.00   Educational Grants
American Chemist Society            $3,000.00   Educational Grants
American College of                $10,000.00   Corporate Sponsorships
 Gastroenterology
American College of                $90,000.00   Corporate Sponsorships
 Gastroenterology
American College of                $90,000.00   Corporate Sponsorships
 Gastroenterology
American College of                $60,000.00   Corporate Sponsorships
 Gastroenterology
American College of                $60,000.00   Corporate Sponsorships
 Gastroenterology
American College of               $450,000.00   Charitable Donations
 Gastroenterology
American College of               $100,000.00   Corporate Sponsorships
 Gastroenterology
American College of               $125,000.00   Corporate Sponsorships
 Gastroenterology
American College of                $30,000.00   Charitable Donations
 Laboratory Animal Medicine
American College of                $32,500.00   Corporate Sponsorships
 Obstetricians and
 Gynecologists
American College of                $25,000.00   Corporate Sponsorships
 Osteopathic Family
 Physicians of California
American College of                $35,000.00   Corporate Sponsorships
 Osteopathic Obstetricians
 and Gynecologists
American College of                $57,000.00   Corporate Sponsorships
 Physician Foundation
American College of                $25,000.00   Educational Grants
 Rheumatology
American College of                $70,000.00   Corporate Sponsorships
 Rheumatology
American College of                $25,000.00   Educational Grants
 Rheumatology
American College of                $35,000.00   Educational Grants
 Rheumatology
American College of                $50,000.00   Educational Grants
 Rheumatology
American College of                $50,000.00   Corporate Sponsorships
 Rheumatology
American College of             $2,000,000.00   Corporate Sponsorships
 Rheumatology Research and
 Education Foundation
American Congress of                $3,000.00   Corporate Sponsorships
 Obstetricians and
 Gynecologists
American Congress of                $9,500.00   Corporate Sponsorships
 Obstetricians and
 Gynecologists
American Congress of               $10,000.00   Corporate Sponsorships
 Obstetricians and
 Gynecologists
American Congress of                $2,250.00   Corporate Sponsorships
 Obstetricians and
 Gynecologists
American Congress of               $25,000.00   Educational Grants
 Obstetricians and
 Gynecologists--Hawaii
 Section District Viii
American Congress of               $32,500.00   Corporate Sponsorships
 Obstetricians and
 Gynecologists--Hawaii
 Section District Viii
American Congress of               $15,000.00   Corporate Sponsorships
 Obstetricians and
 Gynecologists--Hawaii
 Section District Viii
American Congress of               $38,400.00   Corporate Sponsorships
 Obstetricians and
 Gynecologists--Hawaii
 Section District Viii
American Congress of                $2,500.00   Corporate Sponsorships
 Obstetricians and
 Gynecologists Montana
 Section
American                          $278,000.00   Educational Grants
 Gastroenterological
 Association Institute
American                           $46,325.00   Corporate Sponsorships
 Gastroenterological
 Association Institute
American                           $50,000.00   Corporate Sponsorships
 Gastroenterological
 Association Institute
American                           $90,000.00   Corporate Sponsorships
 Gastroenterological
 Association Institute
American                          $200,000.00   Educational Grants
 Gastroenterological
 Association Institute
American                           $40,000.00   Educational Grants
 Gastroenterological
 Association Institute
American Gastrointestinal         ($2,094.95)   Educational Grants
 Association
American Kdny Fund                  $5,000.00   Corporate Sponsorships
American Liver Foundation         $300,000.00   Corporate Sponsorships
American Liver Foundation           $1,000.00   Corporate Sponsorships
American Liver Foundation           $7,500.00   Corporate Sponsorships
American Liver Foundation           $2,500.00   Corporate Sponsorships
American Liver Foundation          $10,000.00   Educational Grants
American Liver Foundation           $2,500.00   Corporate Sponsorships
American Liver Foundation           $5,000.00   Corporate Sponsorships
American Liver Foundation          $50,000.00   Educational Grants
American Liver Foundation          $86,000.00   Corporate Sponsorships
American Liver Foundation          $25,000.00   Educational Grants
American Med Group                  $5,022.40   Corporate Sponsorships
 Associate
American Med Group                  $5,022.40   Corporate Sponsorships
 Associate
American Med Group                  $5,022.40   Corporate Sponsorships
 Associate
American Med Group                  $5,022.40   Corporate Sponsorships
 Associate
American Med Group                  $5,022.40   Corporate Sponsorships
 Associate
American Military Partner          $25,000.00   Corporate Sponsorships
 Association
American Military Partner          $25,000.00   Corporate Sponsorships
 Association
American National Red Cross         $1,000.00   Corporate Sponsorships
 and Its Constituent
 Chapters and Branches
American Neuro Associate           $40,000.00   Educational Grants
American Pancreatic                $25,000.00   Charitable Donations
 Associate
American Pancreatic                $75,000.00   Educational Grants
 Associate
American Pancreatic                $60,000.00   Corporate Sponsorships
 Associate
American Pancreatic                $70,000.00   Corporate Sponsorships
 Associate
American Parkinson Disease          $3,000.00   Corporate Sponsorships
 Association
American Parkinson Disease          $5,000.00   Corporate Sponsorships
 Association
American Parkinson Disease         $75,000.00   Corporate Sponsorships
 Association
American Parkinson Disease         $25,000.00   Corporate Sponsorships
 Association
American Parkinson Disease          $2,000.00   Corporate Sponsorships
 Association
American Parkinson Disease          $5,000.00   Corporate Sponsorships
 Association
American Parkinson Disease          $4,000.00   Corporate Sponsorships
 Association
American Parkinson Disease         $10,000.00   Educational Grants
 Association
American Pharmacists               $15,000.00   Corporate Sponsorships
 Association (Apha)
American Red Cross of              $10,000.00   Charitable Donations
 Greater Chicago
American Society for               $40,000.00   Corporate Sponsorships
 Reproductive Medicine
American Society for               $10,000.00   Corporate Sponsorships
 Reproductive Medicine
American Society for                $6,000.00   Corporate Sponsorships
 Reproductive Medicine
American Society of                $17,500.00   Corporate Sponsorships
 Anesthesiologists
American Society of                $15,000.00   Educational Grants
 Hematology
American Society of               $544,550.00   Corporate Sponsorships
 Hematology
American Society of                $60,000.00   Educational Grants
 Hematology
American Society of                $50,000.00   Fellowships and
 Hematology                                      Scholarships
American Society of                $20,000.00   Educational Grants
 Hematology
American Society of                $50,000.00   Educational Grants
 Hematology
American Statistical               $26,500.00   Corporate Sponsorships
 Associate
American Thyroid Associate         $30,000.00   Educational Grants
 Inc.
American Uroligical                 $3,500.00   Corporate Sponsorships
 Associate Northeastern
 Section
American Urological                $25,000.00   Corporate Sponsorships
 Associate Education and
 Research Inc.
American Urological                $50,000.00   Charitable Donations
 Associate Education and
 Research Inc.
American Urological                $20,000.00   Educational Grants
 Associate Education and
 Research Inc.
American Urological                $50,000.00   Educational Grants
 Associate Education and
 Research Inc.
American Urological                $10,000.00   Corporate Sponsorships
 Associate Inc. Western
 Section
American Urological                $35,000.00   Corporate Sponsorships
 Associate Inc. Western
 Section
American Urological                 $2,000.00   Corporate Sponsorships
 Association--New York
 Section
American Urological                $25,000.00   Corporate Sponsorships
 Association--Southeast
 Section
American Urological                 $5,800.00   Corporate Sponsorships
 Association--Southeast
 Section
American Urological                $10,000.00   Charitable Donations
 Association Foundation
Americans for Med Progress         $90,000.00   Charitable Donations
Americas Hepato--Pancreato--       $35,750.00   Corporate Sponsorships
 Biliary A
Angel Foundation                    $5,000.00   Corporate Sponsorships
Angel Foundation                   $10,000.00   Corporate Sponsorships
Angela Hospice Homecare             $2,500.00   Charitable Donations
Answer2cancer                       $3,000.00   Corporate Sponsorships
Arizona State Association           $3,500.00   Corporate Sponsorships
 of Physician Assistants
Arizona United Rheumatology        $10,000.00   Corporate Sponsorships
 Alliance--Aura
Arkansas Prostate Cancer            $2,000.00   Corporate Sponsorships
 Foundation
Arkansas Rheumatology              $10,000.00   Corporate Sponsorships
 Association
Arkansas Urology Society            $1,250.00   Corporate Sponsorships
Arthritis Foundation              $100,000.00   Fellowships and
                                                 Scholarships
Arthritis Foundation               $25,000.00   Corporate Sponsorships
Arthritis Foundation              $175,000.00   Corporate Sponsorships
Arthritis Foundation               $40,000.00   Corporate Sponsorships
Arthritis Foundation                $2,000.00   Corporate Sponsorships
Arthritis Foundation               $25,000.00   Corporate Sponsorships
Arthritis Foundation                $5,000.00   Charitable Donations
Arthritis Foundation                $2,500.00   Patient Support
Arthritis Foundation                $5,000.00   Patient Support
Arthritis Foundation               $30,000.00   Corporate Sponsorships
Arthritis Foundation               $25,000.00   Corporate Sponsorships
Arthritis Foundation               $10,500.00   Patient Support
Arthritis Foundation               $20,000.00   Patient Support
Arthritis Foundation               $10,000.00   Charitable Donations
Arthritis Foundation                $7,500.00   Patient Support
Arthritis Foundation               $30,000.00   Corporate Sponsorships
Arthritis Foundation                $2,500.00   Corporate Sponsorships
Arthritis Foundation               $10,000.00   Corporate Sponsorships
Arthritis Foundation                $1,595.00   Patient Support
Arthritis Foundation                $1,650.00   Corporate Sponsorships
Arthritis Foundation                $5,000.00   Corporate Sponsorships
Arthritis Foundation               $10,000.00   Corporate Sponsorships
Arthritis Foundation               $10,000.00   Corporate Sponsorships
Arthritis Foundation                $5,000.00   Corporate Sponsorships
Arthritis Foundation                $5,000.00   Corporate Sponsorships
Arthritis Foundation                $2,500.00   Corporate Sponsorships
Arthritis Foundation                  $300.00   Corporate Sponsorships
Arthritis Foundation                $2,500.00   Corporate Sponsorships
Arthritis Foundation                $3,000.00   Corporate Sponsorships
Arthritis Foundation                $5,000.00   Corporate Sponsorships
Arthritis Foundation              $250,000.00   Corporate Sponsorships
Arthritis Foundation              $400,000.00   Corporate Sponsorships
Arthritis Foundation                $5,000.00   Educational Grants
Arthritis Foundation               $40,000.00   Corporate Sponsorships
Arthritis Foundation               $25,000.00   Corporate Sponsorships
Arthritis Foundation              $259,000.00   Corporate Sponsorships
Arthritis Foundation              $100,000.00   Fellowships and
                                                 Scholarships
Arthritis Foundation                $2,000.00   Corporate Sponsorships
Arthritis Foundation              $175,000.00   Corporate Sponsorships
Arthritis Foundation              $300,000.00   Corporate Sponsorships
Arthritis Patient Services         $19,500.00   Charitable Donations
Arts of Healing Foundation          $2,500.00   Corporate Sponsorships
ASCO Conquer Cancer               $100,000.00   Charitable Donations
 Foundation
ASCO Conquer Cancer                $40,000.00   Educational Grants
 Foundation
ASCO Conquer Cancer                $60,000.00   Fellowships and
 Foundation                                      Scholarships
ASCO Conquer Cancer                $75,000.00   Fellowships and
 Foundation                                      Scholarships
ASCO Conquer Cancer                $30,000.00   Educational Grants
 Foundation
ASCO Conquer Cancer                $30,000.00   Fellowships and
 Foundation                                      Scholarships
ASCO Conquer Cancer                $10,000.00   Educational Grants
 Foundation
ASCO Conquer Cancer                $30,000.00   Educational Grants
 Foundation
ASCO Conquer Cancer                $30,000.00   Educational Grants
 Foundation
ASCO Conquer Cancer                $60,000.00   Educational Grants
 Foundation
ASCO Conquer Cancer                $50,000.00   Educational Grants
 Foundation
ASCO Conquer Cancer                $25,000.00   Educational Grants
 Foundation
ASCO Conquer Cancer               $100,000.00   Charitable Donations
 Foundation
ASCO Conquer Cancer                $30,000.00   Fellowships and
 Foundation                                      Scholarships
ASCO Conquer Cancer                $60,000.00   Fellowships and
 Foundation                                      Scholarships
ASCO Conquer Cancer                $75,000.00   Fellowships and
 Foundation                                      Scholarships
ASCO Conquer Cancer                $22,000.00   Educational Grants
 Foundation
ASHP Foundation                    $75,000.00   Fellowships and
                                                 Scholarships
Aspen Cancer Conference            $10,000.00   Educational Grants
 Inc.
Associate de Enfermeria             $6,700.00   Corporate Sponsorships
 Oncologica y Hematologica
 de Puerto Rico Inc.
Associate de                       $10,000.00   Corporate Sponsorships
 Gastroenterologia y
 Hepatologia Pediatrica de
 Puerto Rico Aghppr
Associate de Hematologia y          $5,000.00   Corporate Sponsorships
 Oncologia Medica de Puerto
 Rico
Associate de Hematologia y         $12,000.00   Corporate Sponsorships
 Oncologia Medica de Puerto
 Rico
Associate de Hematologia y          $3,000.00   Corporate Sponsorships
 Oncologia Medica de Puerto
 Rico
Associate de Hematologia y         $11,000.00   Corporate Sponsorships
 Oncologia Medica de Puerto
 Rico
Associate de Reumatologos          $15,000.00   Corporate Sponsorships
 de Puerto Rico
Associate Medicos Pediatras         $6,500.00   Corporate Sponsorships
 Region Este Ampre
Associate Medicos Pediatras         $6,500.00   Corporate Sponsorships
 Region Este Ampre
Associate of Physician              $2,950.00   Corporate Sponsorships
 Assistants in Oncology
 Inc.
Associate of Physician             $35,000.00   Corporate Sponsorships
 Assistants in Oncology
 Inc.
Associate of Professors of         $50,000.00   Corporate Sponsorships
 Gyn and Obstetrician
Association of Community           $30,000.00   Educational Grants
 Cancer Centers (Accc)
Association of                      $5,000.00   Corporate Sponsorships
 Frontotemporal
 Degeneration
Association of Idaho                $1,500.00   Corporate Sponsorships
 Rheumatologists Inc.
Association of Physicians           $1,500.00   Corporate Sponsorships
 of Pakistani Descent of
 North America (Appna)--New
 York Chapter
Association of VA                  $15,500.00   Corporate Sponsorships
 Hematology Oncology
Association of Women in            $40,000.00   Corporate Sponsorships
 Rheumatology
Association of Women in            $40,000.00   Corporate Sponsorships
 Rheumatology
Awesome Enablers LLC              $250,000.00   Corporate Sponsorships
Awesome Enablers LLC              $250,000.00   Corporate Sponsorships
Baylor College Medicine           $100,000.00   Fellowships and
 Infusion Dis                                    Scholarships
Baylor Scott and White              $5,000.00   Educational Grants
 Health
Bellaire Crohns and Colitis        $15,000.00   Corporate Sponsorships
 Foundation
Bellaire Crohns and Colitis         $5,000.00   Corporate Sponsorships
 Foundation
Bellaire Crohns and Colitis       $400,000.00   Corporate Sponsorships
 Foundation
Bendcare                          $434,000.00   Corporate Sponsorships
Beth Israel Deaconess              $40,000.00   Fellowships and
 Medical Center                                  Scholarships
Beth Israel Deaconess              $40,000.00   Fellowships and
 Medical Center                                  Scholarships
Beth Israel Deaconess               $3,500.00   Educational Grants
 Medical Center
Betty and Milton Katz               $1,500.00   Corporate Sponsorships
 Jewish Community Center
Bexar County Physician              $6,250.00   Corporate Sponsorships
 Assistant Society
Big Brothers Big Sisters of        $20,000.00   Charitable Donations
 Metro Chicago
Bio Ascend LLC                     $50,000.00   Corporate Sponsorships
Bio Ascend LLC                     $25,000.00   Corporate Sponsorships
Biomod Foundation                   $1,500.00   Corporate Sponsorships
Biotechnology Industry            $155,000.00   Corporate Sponsorships
 Organization
Biotechnology Industry            $290,000.00   Corporate Sponsorships
 Organization
Biotechnology Industry             $25,000.00   Corporate Sponsorships
 Organization
Biotechnology Industry             $56,000.00   Corporate Sponsorships
 Organization
Black Health Matters                $5,000.00   Corporate Sponsorships
Board of Trustees of The            $1,500.00   Corporate Sponsorships
 Univ of Illinois
Bonnie J Addario Lung              $50,000.00   Patient Support
 Cancer Foundation
Bonnie J Addario Lung               $5,000.00   Corporate Sponsorships
 Cancer Foundation
Borland Groover Clinic                $750.00   Corporate Sponsorships
Boston College School of           $10,000.00   Corporate Sponsorships
 Nursing
Boston Society Inc.                 $3,000.00   Educational Grants
Boston Taiwanese                    $2,500.00   Educational Grants
 Biotechnology Association
 Inc.
Brian Grant Foundation             $85,000.00   Educational Grants
Brian Grant Foundation             $15,000.00   Corporate Sponsorships
Brigham and Women's                 $7,000.00   Educational Grants
 Hospital, Inc.
Business Health Coalition           $5,000.00   Corporate Sponsorships
 Foundation
California Associate of            $10,000.00   Corporate Sponsorships
 Physician Groups
California Life Sciences           $20,000.00   Corporate Sponsorships
 Association
California Life Sciences            $1,500.00   Corporate Sponsorships
 Association
Cancer and Leukemia Group B        $30,000.00   Educational Grants
 Foundation
Cancer and Leukemia Group B        $50,000.00   Fellowships and
 Foundation                                      Scholarships
Cancer Care                        $25,000.00   Charitable Donations
Cancer Care                        $75,000.00   Charitable Donations
Cancer Care                        $25,000.00   Educational Grants
Cancer Care                        $25,000.00   Educational Grants
Cancer Care                       $100,000.00   Educational Grants
Cancer Care                       $100,000.00   Educational Grants
Cancer Foundation for New           $2,500.00   Corporate Sponsorships
 Mexico
Cancer Foundation for New           $2,500.00   Corporate Sponsorships
 Mexico
Cancer Molecular Thrpt              $5,000.00   Educational Grants
Cancer Research Institute          $10,000.00   Educational Grants
Cancer Research Institute          $40,000.00   Corporate Sponsorships
Cancer Support Community           $75,000.00   Educational Grants
Cancer Support Community           $75,000.00   Educational Grants
Cancer Wellness Center              $5,000.00   Corporate Sponsorships
Cancercare Co-Payment           $5,000,000.00   Charitable Donations
 Assistance Foundation
Captis Health                       $3,000.00   Corporate Sponsorships
Cardinal Health                   $100,000.00   Corporate Sponsorships
Cardinal Health                   $105,000.00   Corporate Sponsorships
Carevive Systems, Inc.             $75,000.00   Educational Grants
Carevive Systems, Inc.             $75,000.00   Educational Grants
Carevive Systems, Inc.             $75,000.00   Educational Grants
Carevive Systems, Inc.            $125,000.00   Educational Grants
Caring Ambassadors Program          $5,000.00   Corporate Sponsorships
 Inc.
Caring Ambassadors Program         $10,000.00   Corporate Sponsorships
 Inc.
Caring Ambassadors Program         $10,000.00   Corporate Sponsorships
 Inc.
Caring Ambassadors Program         $50,000.00   Charitable Donations
 Inc.
Caring Ambassadors Program         $10,000.00   Charitable Donations
 Inc.
Carti Foundation                   $10,000.00   Corporate Sponsorships
Cascade Aids Project                $5,000.00   Corporate Sponsorships
Case Western Reserve Univ          $20,000.00   Fellowships and
                                                 Scholarships
Cedar Rapids Metro                  $2,000.00   Corporate Sponsorships
 Parkinsons Association
Cedars--Sinai Med Center           $40,000.00   Fellowships and
                                                 Scholarships
Cedars--Sinai Med Center            $8,000.00   Educational Grants
Central Brain Tumor                $30,000.00   Educational Grants
 Registry of The United
 States
Central Savannah River Area         $1,000.00   Corporate Sponsorships
 Csra Parkinson Support
 Group
Chicago Gynecological               $8,000.00   Corporate Sponsorships
 Society
Chicago Urological Soctiey         $12,000.00   Corporate Sponsorships
Childrens Digestive Health         $42,428.00   Corporate Sponsorships
 and Nutrition Foundation
Childrens Hospital of               $2,000.00   Corporate Sponsorships
 Wisconsin
Children's Skin Disease               $600.00   Corporate Sponsorships
 Foundation
Childrens Treehouse                $10,000.00   Charitable Donations
 Foundation
Chimp Haven                        $15,000.00   Charitable Donations
Chinese American                    $3,600.00   Corporate Sponsorships
 Biopharmaceutical Society
Chris Elliott Fund                 $10,000.00   Charitable Donations
Chris Elliott Fund                 $10,000.00   Charitable Donations
Chris Elliott Fund                 $10,000.00   Charitable Donations
Chris Elliott Fund                 $25,000.00   Corporate Sponsorships
Chris Elliott Fund                 $50,000.00   Charitable Donations
Chris Elliott Fund                 $40,000.00   Educational Grants
Chris Elliott Fund                 $10,000.00   Corporate Sponsorships
Chris Elliott Fund                 $10,000.00   Corporate Sponsorships
Chris Elliott Fund                 $20,000.00   Corporate Sponsorships
Chris Elliott Fund                 $20,000.00   Corporate Sponsorships
Chris Elliott Fund                 $25,000.00   Corporate Sponsorships
Chris Elliott Fund                 $10,000.00   Corporate Sponsorships
Christ Hospital Foundation          $5,000.00   Corporate Sponsorships
Chronic Liver Disease             $450,000.00   Educational Grants
 Foundation
Chronic Liver Disease              $75,000.00   Corporate Sponsorships
 Foundation
Chronic Liver Disease              $75,000.00   Corporate Sponsorships
 Foundation
Chronic Liver Disease              $90,000.00   Corporate Sponsorships
 Foundation
Chronic Lymphoytic Leukemia        $50,000.00   Charitable Donations
 Society Inc.
Chronic Lymphoytic Leukemia        $25,075.00   Patient Support
 Society Inc.
Chronic Lymphoytic Leukemia        $75,000.00   Patient Support
 Society Inc.
Chronic Lymphoytic Leukemia        $50,000.00   Patient Support
 Society Inc.
Chronic Lymphoytic Leukemia        $35,000.00   Patient Support
 Society Inc.
Chronic Lymphoytic Leukemia        $75,000.00   Patient Support
 Society Inc.
Cincinnati Childrens               $40,000.00   Fellowships and
 Hospital Medical Center                         Scholarships
City of Hope National Med          $50,000.00   Educational Grants
 Center
Cleveland Clinic                  ($3,131.07)   Educational Grants
 Educational Foundation
Cleveland Clinic                    $5,000.00   Educational Grants
 Educational Foundation
Cleveland Clinic                 ($13,876.68)   Educational Grants
 Educational Foundation
Cleveland Clinic                   $50,000.00   Educational Grants
 Educational Foundation
Cleveland Clinic                  ($7,563.37)   Educational Grants
 Educational Foundation
Cleveland Clinic                   $50,000.00   Educational Grants
 Educational Foundation
Cleveland Clinic                   $20,000.00   Educational Grants
 Educational Foundation
Cleveland Clinic                    $5,000.00   Educational Grants
 Educational Foundation
Cleveland Clinic                   $50,000.00   Educational Grants
 Educational Foundation
Cleveland Clinic                   $50,000.00   Educational Grants
 Educational Foundation
Cleveland Clinic                   $25,000.00   Corporate Sponsorships
 Educational Foundation
Cleveland Clinic Foundation        $55,000.00   Fellowships and
                                                 Scholarships
Cleveland Clinic Minority          $25,000.00   Corporate Sponsorships
 Mens Health Center
Clinical Care Optn LLC              $5,000.00   Educational Grants
Clinical Care Optn LLC             $35,000.00   Educational Grants
Clinical Care Optn LLC             $75,000.00   Educational Grants
Clinical Care Optn LLC             $35,000.00   Educational Grants
Clinical Care Optn LLC             $50,000.00   Educational Grants
Clinical Care Optn LLC             $35,000.00   Educational Grants
Clinical Care Optn LLC           ($35,000.00)   Educational Grants
Clinical Care Optn LLC             $25,000.00   Educational Grants
Clinical Care Optn LLC             $75,000.00   Educational Grants
Clinical Care Optn LLC            $120,000.00   Educational Grants
Clinical Care Optn LLC             $25,000.00   Educational Grants
Clinical Care Optn LLC             $25,000.00   Educational Grants
Clinical Care Optn LLC             $50,000.00   Educational Grants
Clinical Care Optn LLC             $50,000.00   Educational Grants
Clinical Care Optn LLC             $75,000.00   Educational Grants
Clinical Care Optn LLC             $75,000.00   Educational Grants
Clinical Care Optn LLC             $95,000.00   Educational Grants
CLL Global Research                $35,000.00   Patient Support
 Foundation
CLL Global Research                $35,000.00   Educational Grants
 Foundation
Club DE oficiales DE LA               $495.00   Charitable Donations
 Policia DE Puerto Rico
 Inc.
Coalition for Prevention of         $5,000.00   Corporate Sponsorships
 Colorectal Cancer in
 Puerto Rico
Coalition of Texans With            $5,000.00   Corporate Sponsorships
 Disabilities
Coalition of Texans With            $5,000.00   Corporate Sponsorships
 Disabilities
Cockerell Educational              $25,000.00   Corporate Sponsorships
 Foundation
Cockerell Educational              $30,000.00   Corporate Sponsorships
 Foundation
Cody Dieruf Benefit                 $5,000.00   Charitable Donations
 Foundation
Colegio DE Farmaceuticos DE         $4,000.00   Corporate Sponsorships
 Puerto Rico
Colegio DE Farmaceuticos DE         $5,000.00   Corporate Sponsorships
 Puerto Rico
Colegio DE Profesionales DE         $2,000.00   Corporate Sponsorships
 LA Enfermeria DE Puerto
 Rico Inc.
Colegio DE Profesionales DE         $3,000.00   Corporate Sponsorships
 LA Enfermeria DE Puerto
 Rico Inc.
Colegio DE Profesionales DE         $3,000.00   Corporate Sponsorships
 LA Enfermeria DE Puerto
 Rico Inc.
Collaborative Alliance for         $30,000.00   Educational Grants
 Pancreatic Education and
 Research (Caper)
Collaborative Alliance for         $30,000.00   Fellowships and
 Pancreatic Education and                        Scholarships
 Research (Caper)
Collaborative Alliance for          $6,000.00   Fellowships and
 Pancreatic Education and                        Scholarships
 Research (Caper)
College of American                 $5,065.00   Corporate Sponsorships
 Pathologists
College of Lake County              $1,000.00   Charitable Donations
Colorado American Congress         $10,000.00   Corporate Sponsorships
 of Obstetrician Gyn
 Colorado Section
Columbia Univ Med Center            $5,000.00   Educational Grants
Columbia Univ Med Center           $75,000.00   Fellowships and
                                                 Scholarships
Community Center                   $10,000.00   Corporate Sponsorships
Community Center                   $10,000.00   Corporate Sponsorships
Community Foundation                $5,000.00   Corporate Sponsorships
Community Foundation                $1,500.00   Corporate Sponsorships
Community Initiatives              $40,000.00   Corporate Sponsorships
Community Initiatives              $25,000.00   Patient Support
Community Initiatives               $1,500.00   Charitable Donations
Community Liver Alliance           $15,000.00   Corporate Sponsorships
Community Liver Alliance              $500.00   Corporate Sponsorships
Community Liver Alliance            $1,500.00   Corporate Sponsorships
Community Oncology Alliance        $20,000.00   Corporate Sponsorships
Connecticut Dermatology             $3,722.25   Corporate Sponsorships
 Society
Connecticut Dermatology             $3,500.00   Corporate Sponsorships
 Society
Connecting To Cure Crohns          $10,000.00   Corporate Sponsorships
 and Colitis
Consortium of Multiple             $59,150.00   Educational Grants
 Sclerosis Centers
Consortium of Multiple              ($452.00)   Educational Grants
 Sclerosis Centers
Consortium of Multiple              ($341.36)   Educational Grants
 Sclerosis Centers
Continuing Educational            $350,000.00   Educational Grants
 Alliance LLC
Continuing Educational            $375,000.00   Educational Grants
 Alliance LLC
Continuing Educational              ($623.00)   Educational Grants
 Alliance LLC
Continuing Educational            $200,000.00   Educational Grants
 Alliance LLC
Continuing Educational             $75,000.00   Educational Grants
 Alliance LLC
Continuing Educational            $300,000.00   Educational Grants
 Alliance LLC
Cornell Univ Weill Med             $15,000.00   Educational Grants
 College
Cornell Univ Weill Med              $3,000.00   Educational Grants
 College
Cornerstone Health Inc.            $90,000.00   Educational Grants
Cornerstone Health Inc.            $50,000.00   Educational Grants
Cradles To Crayons Inc.               $300.00   Charitable Donations
Cristo Rey St Martin                $7,500.00   Corporate Sponsorships
 College Prep
Crohns and Colitis                  $2,500.00   Corporate Sponsorships
 Foundation of America
Crohns and Colitis                  $5,000.00   Corporate Sponsorships
 Foundation of America
Crohns and Colitis                  $1,500.00   Corporate Sponsorships
 Foundation of America
Crohns and Colitis                  $2,500.00   Corporate Sponsorships
 Foundation of America
Crohns and Colitis                  $5,000.00   Corporate Sponsorships
 Foundation of America
Crohns and Colitis                 $15,000.00   Corporate Sponsorships
 Foundation of America
Crohns and Colitis                 $10,000.00   Corporate Sponsorships
 Foundation of America
Crohns and Colitis                 $20,000.00   Charitable Donations
 Foundation of America
Crohns and Colitis                 $40,000.00   Patient Support
 Foundation of America
Crohns and Colitis                $150,000.00   Corporate Sponsorships
 Foundation of America
Crohns and Colitis                  $5,000.00   Corporate Sponsorships
 Foundation of America
Crohns and Colitis                 $90,000.00   Patient Support
 Foundation of America
Crohns and Colitis                $250,000.00   Educational Grants
 Foundation of America
Crohns and Colitis                  $2,500.00   Corporate Sponsorships
 Foundation of America
Crohns and Colitis                 $25,000.00   Corporate Sponsorships
 Foundation of America
Crohns and Colitis                  $1,000.00   Corporate Sponsorships
 Foundation of America
Crohns and Colitis                  $1,000.00   Corporate Sponsorships
 Foundation of America
Crohns and Colitis                  $2,500.00   Corporate Sponsorships
 Foundation of America
Crohns and Colitis                  $3,500.00   Corporate Sponsorships
 Foundation of America
Crohns and Colitis                  $3,000.00   Corporate Sponsorships
 Foundation of America
Crohns and Colitis                 $25,000.00   Educational Grants
 Foundation of America
Crohns and Colitis                 $25,000.00   Educational Grants
 Foundation of America
Crohns and Colitis                 $25,000.00   Educational Grants
 Foundation of America
Crohns and Colitis                 $10,000.00   Corporate Sponsorships
 Foundation of America
Crohns and Colitis                  $2,500.00   Corporate Sponsorships
 Foundation of America
Crohns and Colitis                  $5,000.00   Corporate Sponsorships
 Foundation of America
Crohns and Colitis                  $5,000.00   Corporate Sponsorships
 Foundation of America
Crohns and Colitis                  $2,500.00   Corporate Sponsorships
 Foundation of America
Crohns and Colitis                  $5,000.00   Corporate Sponsorships
 Foundation of America
Crohns and Colitis                  $7,500.00   Corporate Sponsorships
 Foundation of America
Crohns and Colitis                  $5,000.00   Corporate Sponsorships
 Foundation of America
Crohns and Colitis                  $5,000.00   Corporate Sponsorships
 Foundation of America
Crohns and Colitis                  $1,000.00   Corporate Sponsorships
 Foundation of America
Crohns and Colitis                 $25,000.00   Corporate Sponsorships
 Foundation of America
Crohns and Colitis                  $1,500.00   Corporate Sponsorships
 Foundation of America
Crohns and Colitis                  $2,500.00   Corporate Sponsorships
 Foundation of America
Crohns and Colitis                  $3,500.00   Corporate Sponsorships
 Foundation of America
Crohns and Colitis                  $2,500.00   Corporate Sponsorships
 Foundation of America
Crohns and Colitis                  $5,000.00   Corporate Sponsorships
 Foundation of America
Crohns and Colitis                  $7,500.00   Corporate Sponsorships
 Foundation of America
Crohns and Colitis                 $10,000.00   Corporate Sponsorships
 Foundation of America
Crohns and Colitis                 $10,000.00   Corporate Sponsorships
 Foundation of America
Crohns and Colitis                 $25,000.00   Corporate Sponsorships
 Foundation of America
Crohns and Colitis                $250,000.00   Educational Grants
 Foundation of America
Curators of The Univ of             $1,000.00   Charitable Donations
 Missouri
Curepsp Inc.                        $5,000.00   Corporate Sponsorships
Curepsp Inc.                        $2,500.00   Patient Support
Curepsp Inc.                       $30,000.00   Corporate Sponsorships
Curepsp Inc.                       $45,500.00   Corporate Sponsorships
Curepsp Inc.                       $30,000.00   Charitable Donations
Curesearch for Childrens           $15,000.00   Charitable Donations
 Cancer
Cystic Fibrosis Foundation          $1,500.00   Corporate Sponsorships
Cystic Fibrosis Foundation         $25,000.00   Corporate Sponsorships
Cystic Fibrosis Foundation          $2,000.00   Corporate Sponsorships
Cystic Fibrosis Foundation          $2,000.00   Corporate Sponsorships
Cystic Fibrosis Foundation          $1,750.00   Corporate Sponsorships
Cystic Fibrosis Foundation          $3,000.00   Corporate Sponsorships
Cystic Fibrosis Foundation          $5,000.00   Corporate Sponsorships
Cystic Fibrosis Foundation          $2,500.00   Corporate Sponsorships
Cystic Fibrosis Foundation          $2,500.00   Corporate Sponsorships
Cystic Fibrosis Foundation          $5,000.00   Corporate Sponsorships
Cystic Fibrosis Foundation          $1,500.00   Corporate Sponsorships
Cystic Fibrosis Foundation          $2,500.00   Corporate Sponsorships
Cystic Fibrosis Foundation          $2,500.00   Corporate Sponsorships
Cystic Fibrosis Foundation          $2,500.00   Corporate Sponsorships
Cystic Fibrosis Foundation          $1,000.00   Corporate Sponsorships
Cystic Fibrosis Foundation          $5,500.00   Corporate Sponsorships
Cystic Fibrosis Foundation          $2,500.00   Corporate Sponsorships
Cystic Fibrosis Foundation          $3,500.00   Corporate Sponsorships
Cystic Fibrosis Foundation            $500.00   Corporate Sponsorships
Cystic Fibrosis Foundation         $10,000.00   Charitable Donations
Cystic Fibrosis Foundation          $1,000.00   Corporate Sponsorships
Cystic Fibrosis Foundation          $2,500.00   Corporate Sponsorships
Cystic Fibrosis Foundation          $2,500.00   Corporate Sponsorships
Cystic Fibrosis Foundation          $6,000.00   Corporate Sponsorships
Cystic Fibrosis Foundation          $7,500.00   Corporate Sponsorships
Cystic Fibrosis Foundation          $7,500.00   Corporate Sponsorships
Cystic Fibrosis Foundation          $4,000.00   Corporate Sponsorships
Cystic Fibrosis Foundation            $250.00   Corporate Sponsorships
Cystic Fibrosis Foundation          $7,500.00   Corporate Sponsorships
Cystic Fibrosis Foundation          $2,500.00   Corporate Sponsorships
Cystic Fibrosis Foundation          $8,000.00   Corporate Sponsorships
Cystic Fibrosis Foundation         $12,500.00   Corporate Sponsorships
Cystic Fibrosis Foundation        $161,000.00   Corporate Sponsorships
Cystic Fibrosis Foundation          $5,000.00   Corporate Sponsorships
Cystic Fibrosis Foundation          $2,500.00   Corporate Sponsorships
Cystic Fibrosis Foundation          $2,500.00   Corporate Sponsorships
Cystic Fibrosis Foundation          $1,500.00   Corporate Sponsorships
Cystic Fibrosis Foundation          $1,000.00   Corporate Sponsorships
Cystic Fibrosis Foundation          $3,500.00   Corporate Sponsorships
Cystic Fibrosis Foundation          $5,000.00   Corporate Sponsorships
Cystic Fibrosis Foundation            $500.00   Corporate Sponsorships
Cystic Fibrosis Foundation            $750.00   Corporate Sponsorships
Cystic Fibrosis Foundation          $1,000.00   Corporate Sponsorships
Cystic Fibrosis Foundation          $2,500.00   Corporate Sponsorships
Cystic Fibrosis Foundation          $3,500.00   Corporate Sponsorships
Cystic Fibrosis Foundation         $10,000.00   Charitable Donations
Cystic Fibrosis Foundation        $750,000.00   Corporate Sponsorships
Cystic Fibrosis Research            $5,000.00   Corporate Sponsorships
 Fund Emilys Entourage
Cystic Fibrosis Research           $20,000.00   Corporate Sponsorships
 Inc.
Cystic Fibrosis Research            $3,000.00   Corporate Sponsorships
 Inc.
Cystic Fibrosis Research            $6,000.00   Corporate Sponsorships
 Inc.
Cystic Fibrosis Research            $7,000.00   Corporate Sponsorships
 Inc.
Cystic Fibrosis Research           $10,000.00   Corporate Sponsorships
 Inc.
Cystic Fibrosis Research           $12,000.00   Corporate Sponsorships
 Inc.
Cystic Fibrosis Research           $12,000.00   Corporate Sponsorships
 Inc.
Dade County Medical                 $5,000.00   Educational Grants
 Association
Dahshu                              $5,000.00   Corporate Sponsorships
Dallas Area Parkinsonism            $2,500.00   Corporate Sponsorships
 Society
Dana Farber Cancer                 $25,000.00   Educational Grants
 Institute
Dana Farber Cancer                $100,000.00   Corporate Sponsorships
 Institute, Inc.
Dava Oncology LP                   $37,500.00   Corporate Sponsorships
Davis Phinney Foundation           $30,000.00   Patient Support
Davis Phinney Foundation           $80,000.00   Corporate Sponsorships
Davis Phinney Foundation           $30,000.00   Patient Support
Davis Phinney Foundation           $15,000.00   Patient Support
Davis Phinney Foundation           $15,000.00   Educational Grants
Davis Phinney Foundation           $15,000.00   Educational Grants
Davis Phinney Foundation           $15,000.00   Educational Grants
Dermatologic Society of           $100,000.00   Corporate Sponsorships
 Greater New York
Dermatology Education              $50,000.00   Corporate Sponsorships
 Foundation
Dermatology Foundation            $135,000.00   Charitable Donations
Dermatology Foundation             $50,000.00   Corporate Sponsorships
Dermatology Nurses                 $18,000.00   Corporate Sponsorships
 Associate
Dermatology PA Foundation           $2,700.00   Corporate Sponsorships
Digestive Disease Week             $32,400.00   Corporate Sponsorships
Digestive Disease Week             $80,000.00   Corporate Sponsorships
Digestive Disease Week            $255,300.00   Corporate Sponsorships
Digestive Health Foundation        $50,000.00   Corporate Sponsorships
Direct Relief                      $25,000.00   Charitable Donations
Direct Relief                  $10,000,000.00   Charitable Donations
Direct Relief                  $25,000,000.00   Charitable Donations
Direct Relief                   $5,000,000.00   Charitable Donations
Direct Relief                  $10,000,000.00   Charitable Donations
Doctor Solomon Carter              $10,000.00   Educational Grants
 Fuller Mental Health
 Center
Doctor Solomon Carter              $50,000.00   Educational Grants
 Fuller Mental Health
 Center
Drew University Health              $2,500.00   Educational Grants
 Services
Drexel Unviersity                  $55,000.00   Fellowships and
                                                 Scholarships
Drugs for Neglected                $10,000.00   Charitable Donations
 Diseases Initiative North
 America Inc.
East Tennessee Foundation           $1,500.00   Corporate Sponsorships
Ecog Research and Education        $20,000.00   Educational Grants
 Foundation Inc.
Ecog Research and Education        $20,000.00   Educational Grants
 Foundation Inc.
Economic Alliance for               $5,000.00   Corporate Sponsorships
 Michigan
Eisenhower Desert                ($30,000.00)   Educational Grants
 Orthopedic Center
Eisenhower Desert                  $75,000.00   Educational Grants
 Orthopedic Center
Eisenhower Desert                 $300,000.00   Educational Grants
 Orthopedic Center
Eisenhower Desert                  $95,000.00   Educational Grants
 Orthopedic Center
Eisenhower Desert                  $90,000.00   Educational Grants
 Orthopedic Center
Eisenhower Desert                 $563,360.00   Educational Grants
 Orthopedic Center
Eisenhower Desert                  $50,000.00   Educational Grants
 Orthopedic Center
Eisenhower Desert                  $35,100.00   Educational Grants
 Orthopedic Center
Eisenhower Desert                 $250,000.00   Educational Grants
 Orthopedic Center
Eisenhower Desert                 $475,000.00   Educational Grants
 Orthopedic Center
Eisenhower Desert                  $50,000.00   Educational Grants
 Orthopedic Center
Embarcadero Lions Club of           $2,500.00   Corporate Sponsorships
 Sacramento
Employers Health Coalition          $5,000.00   Corporate Sponsorships
Endocrine Education Inc.           $25,000.00   Educational Grants
Endocrine Society                  $25,000.00   Educational Grants
Endocrine Society                  $25,000.00   Educational Grants
Endocrine Society                ($10,928.00)   Educational Grants
Endocrine Society                  $20,000.00   Educational Grants
Endometriosis Associate            $50,000.00   Charitable Donations
Endometriosis Foundation of        $30,000.00   Corporate Sponsorships
 America
Enzyme Mechanism Conference         $2,500.00   Educational Grants
Epilepsy Association of             $7,500.00   Corporate Sponsorships
 Central Florida
Epilepsy Foundation                $15,000.00   Corporate Sponsorships
Epilepsy Foundation of              $5,000.00   Corporate Sponsorships
 Florida
Epilepsy Foundation of             $10,000.00   Corporate Sponsorships
 Michigan
Ethiopian Community                 $2,000.00   Corporate Sponsorships
 Association of Greater
 Philadelphia
Excellence in                     $100,000.00   Corporate Sponsorships
 Gastroenterology Education
 LLC
Excellence in                     $110,000.00   Corporate Sponsorships
 Gastroenterology Education
 LLC
Excellence in Rheumatology        $100,000.00   Corporate Sponsorships
 Education LLC
Family Reach Foundation         $5,000,000.00   Charitable Donations
Federation of American              $2,000.00   Educational Grants
 Society for Experimental
 Biology Faseb
Federation of American              $2,000.00   Educational Grants
 Society for Experimental
 Biology Faseb
Federation of American              $2,000.00   Educational Grants
 Society for Experimental
 Biology Faseb
Federation of American              $2,000.00   Educational Grants
 Society for Experimental
 Biology Faseb
Federation of Clinical             $20,000.00   Educational Grants
 Immunology Society
Federation of Clinical             $20,000.00   Educational Grants
 Immunology Society
Federation of Clinical             $12,500.00   Educational Grants
 Immunology Society
Federation of Clinical             $20,000.00   Fellowships and
 Immunology Society                              Scholarships
Feed My Starving Children             $500.00   Charitable Donations
Feinstein Institute for Med       $243,900.00   Educational Grants
 Research
Fibroid Foundation                 $90,000.00   Charitable Donations
Fibroid Foundation                 $95,000.00   Charitable Donations
Florida Academy of Family          $18,000.00   Corporate Sponsorships
 Physicians
Florida Atlantic University         $1,000.00   Charitable Donations
 Foundation Inc.
Florida Coalition                  $10,000.00   Corporate Sponsorships
Florida Gastroenterological         $7,500.00   Corporate Sponsorships
 Society
Florida Society of                 $70,000.00   Corporate Sponsorships
 Dermatology Physician
 Assistants Inc.
Florida Society of                 $50,000.00   Corporate Sponsorships
 Rheumatology Inc.
Florida Society of                  $5,000.00   Corporate Sponsorships
 Rheumatology Inc.
Focus Med Communications           $35,000.00   Corporate Sponsorships
Focus Med Communications          $135,000.00   Corporate Sponsorships
Footsteps for Fertility             $1,000.00   Corporate Sponsorships
 Foundation
Force--Facing Our Risk of           $5,000.00   Charitable Donations
 Cancer Emp
Forsyth Area Striders Team            $500.00   Corporate Sponsorships
Foundation Fighting                 $2,500.00   Corporate Sponsorships
 Blindness
Foundation for Biomedical          $50,000.00   Charitable Donations
 Research
Foundation for The National         $5,000.00   Corporate Sponsorships
 Institute of Health
Foundation of Consortium of        $17,500.00   Fellowships and
 Multiple Sclerosis Centers                      Scholarships
 Cmsc
Foundation of Consortium of        $40,000.00   Educational Grants
 Multiple Sclerosis Centers
 Cmsc
Foundation of Consortium of        $32,875.00   Patient Support
 Multiple Sclerosis Centers
 Cmsc
Franklin and Marshall               $1,000.00   Charitable Donations
 College
French American Chemical            $3,000.00   Educational Grants
 Society
Friends of Cancer Research         $25,000.00   Charitable Donations
Friends of Cancer Research         $25,000.00   Corporate Sponsorships
Friends of Cancer Research         $25,000.00   Corporate Sponsorships
Friends of The St Louis            $50,000.00   Corporate Sponsorships
 Univ Liver Center
Fundacion Puertorriquena DE        $17,960.00   Educational Grants
 Pacientes Consult
 Endometriosis
Gastrointestinal and Liver        $150,000.00   Corporate Sponsorships
 Association of The
 Americas Inc.
Gastrointestinal Health            $90,000.00   Corporate Sponsorships
 Foundation Inc.
Gateway for Cancer Research        $10,000.00   Charitable Donations
Genesis Healthcare                  $3,000.00   Corporate Sponsorships
 Foundation
George Washington Univ              $3,000.00   Corporate Sponsorships
Georgia Academy of Family           $3,500.00   Corporate Sponsorships
 Physicians
Georgia Dermatology                $50,000.00   Corporate Sponsorships
 Physican Assistants
Georgia Society of                  $7,500.00   Corporate Sponsorships
 Dermatology and
 Dermatologic Surgery
Georgia Society of                 $75,000.00   Corporate Sponsorships
 Dermatology and
 Dermatologic Surgery
Gildas Club Chicago                $10,000.00   Charitable Donations
Global Academy for Medical         $20,000.00   Corporate Sponsorships
 Education
Global Academy for Medical         $43,750.00   Corporate Sponsorships
 Education
Global Academy for Medical         $40,500.00   Corporate Sponsorships
 Education
Global Academy for Medical         $76,500.00   Corporate Sponsorships
 Education
Global Academy for Medical         $58,500.00   Corporate Sponsorships
 Education
Global Academy for Medical         $76,500.00   Corporate Sponsorships
 Education
Global Healthy Living              $45,000.00   Corporate Sponsorships
 Foundation
Global Healthy Living              $75,000.00   Corporate Sponsorships
 Foundation
Global Oncology                     $5,000.00   Corporate Sponsorships
Good Grief                            $500.00   Corporate Sponsorships
Gordon Research Conferences         $2,500.00   Educational Grants
Gordon Research Conferences         $3,000.00   Educational Grants
Gordon Research Conferences         $1,000.00   Educational Grants
Gordon Research Conferences         $2,500.00   Educational Grants
Gordon Research Conferences         $3,000.00   Educational Grants
Gordon Research Conferences         $1,500.00   Educational Grants
Gordon Research Conferences         $2,000.00   Educational Grants
Gordon Research Conferences         $2,500.00   Educational Grants
Gordon Research Conferences         $2,000.00   Educational Grants
Gordon Research Conferences         $2,000.00   Educational Grants
Gordon Research Conferences         $2,000.00   Educational Grants
Gordon Research Conferences         $2,000.00   Educational Grants
Gordon Research Conferences         $1,000.00   Educational Grants
Gordon Research Conferences         $2,500.00   Educational Grants
Grand Traverse Area                 $1,500.00   Corporate Sponsorships
 Parkinsons Support Group
Gynecologic Oncology Group         $10,000.00   Educational Grants
Gynecologic Oncology Group         $25,000.00   Educational Grants
Gynecologic Oncology Group          $5,500.00   Educational Grants
Gynecologic Oncology Group         $40,000.00   Educational Grants
H Lee Moffitt Cancer Center         $7,500.00   Educational Grants
 and Research Institute
Halo House Foundation              $10,000.00   Corporate Sponsorships
Hamil Kerr Challenge                  $500.00   Corporate Sponsorships
Harborside Press                   $30,400.00   Corporate Sponsorships
Harborside Press                   $80,000.00   Corporate Sponsorships
Hartford Hospital                   $5,000.00   Corporate Sponsorships
Healthcare 21 Business              $1,500.00   Corporate Sponsorships
 Coalition
Healthwell Foundation             $220,000.00   Charitable Donations
Healthy Women                      $30,000.00   Corporate Sponsorships
Heart To Heart                     $15,000.00   Charitable Donations
 International Inc.
Heart To Heart                      $1,000.00   Charitable Donations
 International Inc.
Heart To Heart                      $5,000.00   Charitable Donations
 International Inc.
Henry M Jackson Foundation         $10,000.00   Educational Grants
Hepatitis C Association            $20,000.00   Educational Grants
Hepatitis C Mentor and             $20,000.00   Patient Support
 Support Group The
Hepatitis Education Project        $25,000.00   Corporate Sponsorships
Hermanas Carmelitas Teresas           $393.79   Charitable Donations
 DE San Jose, Inc.
Hidradenitis Suppurativa           $10,000.00   Charitable Donations
 Foundation
HIV Treaters Med Associate          $7,500.00   Corporate Sponsorships
 of Puerto Rico
HMP Communications                 $15,000.00   Corporate Sponsorships
HMP Communications                 $70,000.00   Corporate Sponsorships
Hope Foundation                    $25,000.00   Educational Grants
Hospital of the University         $10,000.00   Educational Grants
 of Pennsylvania
Hospital of the University         $75,000.00   Educational Grants
 of Pennsylvania
Hospital of the University          $5,000.00   Educational Grants
 of Pennsylvania
Hospital of the University         $10,000.00   Educational Grants
 of Pennsylvania
Howard Hanna Children's            $10,000.00   Charitable Donations
 Free Care Fund
Hubbard Street Dance               $10,000.00   Educational Grants
 Chicago
Human Growth Foundation             $5,000.00   Corporate Sponsorships
Human Growth Foundation             $2,000.00   Corporate Sponsorships
Hunt for A Cure                     $1,250.00   Corporate Sponsorships
Huntsman Cancer Foundation            $500.00   Corporate Sponsorships
Huntsman Cancer Foundation          $2,000.00   Corporate Sponsorships
Huntsman Cancer Foundation          $2,500.00   Corporate Sponsorships
IASLC Foundation                   $50,000.00   Fellowships and
                                                 Scholarships
IBD Horizons                        $2,500.00   Corporate Sponsorships
IBD Horizons                        $2,500.00   Corporate Sponsorships
IBD Horizons                       $50,000.00   Corporate Sponsorships
Illinois Academy of Family          $4,500.00   Educational Grants
 Physicians
Illinois Cancercare                 $2,500.00   Corporate Sponsorships
 Foundation
Illinois Society of                $65,000.00   Corporate Sponsorships
 Dermatology Physician
 Assistants
Imedex LLC                         $75,000.00   Educational Grants
Imedex LLC                        ($1,119.00)   Educational Grants
Imedex LLC                         $25,000.00   Educational Grants
Imedex LLC                         $30,000.00   Educational Grants
Imedex LLC                          ($991.00)   Educational Grants
Imedex LLC                         $40,000.00   Educational Grants
Imedex LLC                         $75,000.00   Educational Grants
Imedex LLC                         $40,000.00   Educational Grants
Imedex LLC                        $114,000.00   Corporate Sponsorships
Imerman Angels                      $1,500.00   Charitable Donations
Immune Deficiency                   $9,900.00   Corporate Sponsorships
 Foundation
Impact Education LLC               $75,000.00   Educational Grants
Impact Education LLC               $95,000.00   Educational Grants
Improve Care Now Inc.              $12,500.00   Corporate Sponsorships
Improve Care Now Inc.             $100,000.00   Patient Support
Improve Care Now Inc.              $12,500.00   Corporate Sponsorships
Improve Care Now Inc.              $12,500.00   Corporate Sponsorships
Improve Care Now Inc.              $12,500.00   Corporate Sponsorships
Indian Doc Associate of             $5,000.00   Corporate Sponsorships
 Houston
Indiana Parkinson                   $4,250.00   Corporate Sponsorships
 Foundation
Indy Hematology Education          $30,000.00   Corporate Sponsorships
 Inc.
Indy Hematology Education          $19,000.00   Corporate Sponsorships
 Inc.
Infectious Disease of              $10,000.00   Patient Support
 Puerto Rico
Innovation Foundation Inc.         $55,000.00   Corporate Sponsorships
Institute for Medical and          $15,000.00   Educational Grants
 Nursing Education
Integrated Med Foundation          $15,000.00   Charitable Donations
Integrated Med Foundation           $9,500.00   Corporate Sponsorships
Intellisphere LLC                   $7,000.00   Corporate Sponsorships
Intellisphere LLC                  $15,500.00   Corporate Sponsorships
Intellisphere LLC                  $10,500.00   Corporate Sponsorships
Intellisphere LLC                  $16,000.00   Corporate Sponsorships
Intellisphere LLC                  $18,500.00   Corporate Sponsorships
Intellisphere LLC                  $12,500.00   Corporate Sponsorships
Internaltional Society for         $17,500.00   Corporate Sponsorships
 Pharmacoeconomics and
 Outcomes Research
International Association         $311,000.00   Corporate Sponsorships
 for The Study of Lung
 Cancer
International Association          $15,000.00   Corporate Sponsorships
 for The Study of Lung
 Cancer
International Association          $75,000.00   Corporate Sponsorships
 for The Study of Lung
 Cancer
International Biometric             $3,875.00   Corporate Sponsorships
 Society Eastern North
 American Region
International Dermatology          $70,000.00   Corporate Sponsorships
 Outcome Measures
International Dermatology          $70,000.00   Corporate Sponsorships
 Outcome Measures
International Medical Corps         $5,000.00   Charitable Donations
International Meyoloma            $100,000.00   Corporate Sponsorships
 Foundation
International Meyoloma             $15,000.00   Corporate Sponsorships
 Foundation
International Meyoloma             $25,000.00   Charitable Donations
 Foundation
International Meyoloma             $10,000.00   Educational Grants
 Foundation
International Myeloma              $50,000.00   Corporate Sponsorships
 Society (IMS)
International Organization         $50,000.00   Patient Support
 of Multiple Sclerosis
 Nurses
International Pelvic Pain          $23,000.00   Corporate Sponsorships
 Society
International Pelvic Pain           $5,000.00   Corporate Sponsorships
 Society
International Physician            $75,000.00   Corporate Sponsorships
 Ntwrk Dba International
 Oncology Ntwrk
International Physician            $95,000.00   Corporate Sponsorships
 Ntwrk Dba International
 Oncology Ntwrk
International Physician            $75,000.00   Corporate Sponsorships
 Ntwrk Dba International
 Oncology Ntwrk
International Psoriasis            $25,000.00   Corporate Sponsorships
 Council
International Psoriasis            $50,000.00   Corporate Sponsorships
 Council
International Society for           $5,000.00   Educational Grants
 Antiviral Research
It Takes Guts                       $1,000.00   Corporate Sponsorships
Johns Hopkins Technology           $50,000.00   Educational Grants
 Ventures
Johns Hopkins Technology           $20,000.00   Educational Grants
 Ventures
Johns Hopkins Technology           $40,000.00   Fellowships and
 Ventures                                        Scholarships
Johns Hopkins Technology            $2,500.00   Corporate Sponsorships
 Ventures
Johns Hopkins Technology           $75,000.00   Educational Grants
 Ventures
Johns Hopkins Technology           $25,000.00   Educational Grants
 Ventures
Johns Hopkins Technology           $40,000.00   Fellowships and
 Ventures                                        Scholarships
Johns Hopkins Technology           $40,000.00   Fellowships and
 Ventures                                        Scholarships
Johns Hopkins Technology           $40,000.00   Fellowships and
 Ventures                                        Scholarships
Johns Hopkins Technology           $70,000.00   Corporate Sponsorships
 Ventures
Johns Hopkins Technology           $50,000.00   Fellowships and
 Ventures                                        Scholarships
Johns Hopkins Technology           $10,000.00   Educational Grants
 Ventures
Johns Hopkins University          ($3,916.11)   Educational Grants
Johns Hopkins University          ($2,784.14)   Educational Grants
JWC Covenant Inc.                  $50,000.00   Educational Grants
Kansas Univ Endowment              $40,000.00   Educational Grants
 Association
Kelsey Research Foundation         $40,000.00   Fellowships and
                                                 Scholarships
Kentucky Rural Health              $35,000.00   Corporate Sponsorships
 Association
Kentucky Rural Health              $25,000.00   Corporate Sponsorships
 Association
Kentucky Rural Health               $5,000.00   Corporate Sponsorships
 Association
Laboratorio Clinico Toledo            $900.00   Patient Support
Laboratorio Clinico Toledo          $1,095.00   Patient Support
Laboratorio Clinico Toledo            $900.00   Patient Support
Laboratorio Clinico Toledo          $2,250.00   Patient Support
Laboratorio Clinico Toledo          $5,325.00   Patient Support
Laboratorio Clinico Toledo            $465.00   Patient Support
Laboratorio Clinico Toledo          $1,500.00   Patient Support
Laboratorio Clinico Toledo            $750.00   Patient Support
Laboratorio Clinico Toledo          $1,500.00   Patient Support
Laboratorio Clinico Toledo            $315.00   Patient Support
Laboratorio Clinico Toledo            $705.00   Patient Support
Laboratorio Clinico Toledo          $2,295.00   Patient Support
Laboratorio Clinico Toledo            $348.00   Patient Support
Laboratorio Clinico Toledo            $435.00   Patient Support
Laboratorio Clinico Toledo            $750.00   Patient Support
Laboratorio Clinico Toledo          $1,050.00   Patient Support
Laboratorio Clinico Toledo            $372.00   Patient Support
Laboratorio Clinico Toledo            $255.00   Patient Support
Laboratorio Clinico Toledo            $600.00   Patient Support
Laboratorio Clinico Toledo            $600.00   Patient Support
Laboratorio Clinico Toledo            $825.00   Patient Support
Laboratorio Clinico Toledo            $345.00   Patient Support
Laboratorio Clinico Toledo            $600.00   Patient Support
Laboratorio Clinico Toledo            $750.00   Patient Support
Laboratorio Clinico Toledo          $1,200.00   Patient Support
Laboratorio Clinico Toledo          $1,500.00   Patient Support
Laboratorio Clinico Toledo          $1,125.00   Patient Support
Laboratorio Clinico Toledo            $255.00   Patient Support
Laboratorio Clinico Toledo            $480.00   Patient Support
Laboratorio Clinico Toledo            $750.00   Patient Support
Laboratorio Clinico Toledo          $1,500.00   Patient Support
Laboratorio Clinico Toledo            $705.00   Patient Support
Laboratorio Clinico Toledo            $885.00   Patient Support
Laboratorio Clinico Toledo          $1,695.00   Patient Support
Laboratorio Clinico Toledo            $480.00   Patient Support
Laboratorio Clinico Toledo            $525.00   Patient Support
Laboratorio Clinico Toledo            $915.00   Patient Support
Laboratorio Clinico Toledo          $1,200.00   Patient Support
Laboratorio Clinico Toledo            $600.00   Patient Support
Laboratorio Clinico Toledo            $675.00   Patient Support
Laboratorio Clinico Toledo          $1,200.00   Patient Support
Laboratorio Clinico Toledo          $3,000.00   Patient Support
Laboratorio Clinico Toledo            $900.00   Patient Support
Laboratorio Clinico Toledo            $360.00   Patient Support
Laboratorio Clinico Toledo          $1,290.00   Patient Support
Laboratorio Clinico Toledo            $900.00   Patient Support
Laboratorio Clinico Toledo          $1,200.00   Patient Support
Laboratorio Clinico Toledo            $750.00   Patient Support
Laboratorio Clinico Toledo          $1,500.00   Patient Support
Laboratorio Clinico Toledo          $1,500.00   Patient Support
Laboratorio Clinico Toledo            $930.00   Patient Support
Laboratorio Clinico Toledo          $1,200.00   Patient Support
Laboratorio Clinico Toledo            $675.00   Patient Support
Laboratorio Clinico Toledo            $600.00   Patient Support
Laboratorio Clinico Toledo            $750.00   Patient Support
Laboratorio Clinico Toledo            $525.00   Patient Support
Laboratorio Clinico Toledo            $750.00   Patient Support
Laboratorio Clinico Toledo            $360.00   Patient Support
Laboratorio Clinico Toledo          $1,680.00   Patient Support
Laboratorio Clinico Toledo            $525.00   Patient Support
Laboratorio Clinico Toledo            $600.00   Patient Support
Laboratorio Clinico Toledo            $375.00   Patient Support
Laboratorio Clinico Toledo            $990.00   Patient Support
Laboratorio Clinico Toledo          $1,830.00   Patient Support
Laboratorio Clinico Toledo            $600.00   Patient Support
Laboratorio Clinico Toledo            $600.00   Patient Support
Lahey Hospital and Medical          $3,000.00   Corporate Sponsorships
 Center
Lake County Crisis Center           $5,000.00   Charitable Donations
Lake County Haven                  $10,000.00   Charitable Donations
Large Urology Group                $66,400.00   Corporate Sponsorships
 Practice Associate
Large Urology Group                $20,000.00   Corporate Sponsorships
 Practice Associate
Large Urology Group                $20,000.00   Corporate Sponsorships
 Practice Associate
Large Urology Group                 $5,000.00   Corporate Sponsorships
 Practice Associate
Leukemia and Lymphoma              $50,000.00   Patient Support
 Society Inc.
Leukemia and Lymphoma               $5,000.00   Corporate Sponsorships
 Society Inc.
Leukemia and Lymphoma               $5,000.00   Corporate Sponsorships
 Society Inc.
Leukemia and Lymphoma             $100,000.00   Corporate Sponsorships
 Society Inc.
Leukemia and Lymphoma             $100,000.00   Educational Grants
 Society Inc.
Leukemia and Lymphoma               $2,000.00   Corporate Sponsorships
 Society Inc.
Leukemia and Lymphoma               $5,000.00   Corporate Sponsorships
 Society Inc.
Leukemia and Lymphoma              $95,000.00   Corporate Sponsorships
 Society Inc.
Leukemia and Lymphoma              $70,000.00   Corporate Sponsorships
 Society Inc.
Leukemia and Lymphoma              $50,000.00   Educational Grants
 Society Inc.
Leukemia and Lymphoma              $50,000.00   Educational Grants
 Society Inc.
Leukemia and Lymphoma               $3,500.00   Corporate Sponsorships
 Society Inc.
Leukemia Research                  $50,000.00   Fellowships and
 Foundation Inc.                                 Scholarships
Leukemia Research                  $10,000.00   Corporate Sponsorships
 Foundation Inc.
Leukemia Research                   $5,000.00   Charitable Donations
 Foundation Inc.
Leukemia Research                   $5,000.00   Educational Grants
 Foundation Inc.
Leukemia Research                  $50,000.00   Fellowships and
 Foundation Inc.                                 Scholarships
Linkage To Health Inc.             $25,000.00   Educational Grants
Liver Health Connection            $40,000.00   Educational Grants
Liver Health Connection             $5,000.00   Corporate Sponsorships
Livestrong Foundation              $10,000.00   Charitable Donations
Loma Linda University              $10,000.00   Educational Grants
 School of Medicine
Lung Cancer Alliance               $25,000.00   Corporate Sponsorships
Lung Cancer Research               $25,000.00   Charitable Donations
 Foundation
Lung Cancer Research               $20,000.00   Corporate Sponsorships
 Foundation
Lungevity Foundation                $5,000.00   Corporate Sponsorships
Lungevity Foundation               $25,000.00   Charitable Donations
Lungevity Foundation               $10,000.00   Corporate Sponsorships
Lungevity Foundation               $10,000.00   Educational Grants
Lupus and Allied Diseases          $15,000.00   Corporate Sponsorships
 Association, Inc.
Lymphoma Research                  $10,000.00   Corporate Sponsorships
 Foundation
Lymphoma Research                  $25,000.00   Corporate Sponsorships
 Foundation
Lymphoma Research                  $40,000.00   Corporate Sponsorships
 Foundation
Lymphoma Research                  $10,000.00   Corporate Sponsorships
 Foundation
Lymphoma Research                  $15,000.00   Corporate Sponsorships
 Foundation
Lymphoma Research                  $25,000.00   Corporate Sponsorships
 Foundation
Lymphoma Research                  $50,000.00   Corporate Sponsorships
 Foundation
Magellan Rx Management Inc.        $10,000.00   Corporate Sponsorships
March of Dimes Foundation           $5,000.00   Corporate Sponsorships
Massachusetts General              $30,000.00   Educational Grants
 Hospital
Massachusetts General              $40,000.00   Fellowships and
 Hospital                                        Scholarships
Massachusetts Society for          $10,000.00   Charitable Donations
 Med Research
Mayo Clinic                         $7,500.00   Corporate Sponsorships
Mayo Clinic Scottsdale              $8,000.00   Educational Grants
 Pharmacy
Mayo Clinic Scottsdale             $10,000.00   Educational Grants
 Pharmacy
Mckesson Specialty Health          $60,000.00   Corporate Sponsorships
 Pharmaceuticals and
 Biotechnology Solutions
Mckesson Specialty Health          $25,000.00   Corporate Sponsorships
 Pharmaceuticals and
 Biotechnology Solutions
Mckesson Specialty Health          $65,000.00   Corporate Sponsorships
 Pharmaceuticals and
 Biotechnology Solutions
ME Strong Inc.                      $5,000.00   Corporate Sponsorships
Med--LQ LLC                        $75,000.00   Educational Grants
Med--LQ LLC                        $75,000.00   Educational Grants
Med--LQ LLC                        $75,000.00   Educational Grants
Med Conference Planners             $7,500.00   Corporate Sponsorships
Med Educator Consortium            $10,000.00   Corporate Sponsorships
Med Univ of South Carolina          $2,500.00   Educational Grants
 Foundation
Medical Education Resources        $20,000.00   Corporate Sponsorships
Medical Learning Institute        $148,000.00   Educational Grants
Medical Learning Institute         $95,000.00   Educational Grants
Medical Learning Institute         $55,495.00   Educational Grants
Medical Learning Institute         $50,000.00   Educational Grants
Medical Learning Institute          ($715.00)   Educational Grants
Medical Oncology                   $20,000.00   Corporate Sponsorships
 Association of Southern
 California
Medical Univ of South               $1,250.00   Corporate Sponsorships
 Carolina
Medical Univ of South               $1,250.00   Corporate Sponsorships
 Carolina
Medical Univ of South               $7,500.00   Corporate Sponsorships
 Carolina
Medicinal and Bioorganic            $5,000.00   Educational Grants
 Chemistry Foundation The
Medina Community Clinic             $1,000.00   Corporate Sponsorships
Medscape LLC                      ($7,703.00)   Educational Grants
Medscape LLC                      ($2,475.00)   Educational Grants
Medscape LLC                        ($205.88)   Educational Grants
Medstar Georgetown                    $800.00   Corporate Sponsorships
 Transplant Institute
 Fairfax
Medstar Health Inc.                $10,000.00   Educational Grants
Meeting Designs LLC                $20,000.00   Corporate Sponsorships
Memorial Hermann Foundation         $1,500.00   Corporate Sponsorships
Memorial Hermann Foundation         $5,000.00   Corporate Sponsorships
Memorial Sloan Kettering           $25,000.00   Educational Grants
 Cancer Center
Merriam LLC Dba World Class        $73,085.00   Educational Grants
 Cme
Metavivor Research and              $4,000.00   Charitable Donations
 Support, Inc.
Methodist Dallas Med Center         $5,000.00   Corporate Sponsorships
 Irb
Methodist Hospital                 $25,000.00   Corporate Sponsorships
Metropolitan Chicago Breast         $5,000.00   Charitable Donations
 Cancer
Michael J Fox Foundation           $10,000.00   Corporate Sponsorships
Michael J Fox Foundation            $1,000.00   Corporate Sponsorships
Michael J Fox Foundation          $600,000.00   Corporate Sponsorships
Michael J Fox Foundation           $25,000.00   Corporate Sponsorships
Michael J Fox Foundation           $25,000.00   Corporate Sponsorships
Michigan Parkinson                  $5,000.00   Corporate Sponsorships
 Foundation
Michigan Parkinson                  $3,000.00   Corporate Sponsorships
 Foundation
Michigan Rheumatism Society        $25,000.00   Corporate Sponsorships
Midwest Business Group On           $3,000.00   Corporate Sponsorships
 Health
Midwest Parkinsons                  $1,000.00   Corporate Sponsorships
 Initiative
Miles for Cystic Fibrosis           $2,500.00   Corporate Sponsorships
Miles for Cystic Fibrosis          $15,000.00   Charitable Donations
Minnesota Urological                $5,000.00   Corporate Sponsorships
 Society
Mississippi Arthritis and          $10,000.00   Corporate Sponsorships
 Rheumatism Society
Missouri Hepatitis C               $25,000.00   Educational Grants
 Alliance
MIT Medical Obstetrics and         $10,000.00   Charitable Donations
 Gynecology
Montana Academy of                  $1,500.00   Corporate Sponsorships
 Ophthalmology
Montefiore Med Center              $40,000.00   Fellowships and
                                                 Scholarships
Mount Sinai School of               $2,500.00   Educational Grants
 Medicine
Mount Sinai School of              $30,000.00   Corporate Sponsorships
 Medicine
Mount Sinai School of              $10,000.00   Educational Grants
 Medicine
Mount Sinai School of              $40,000.00   Educational Grants
 Medicine
Mountain Area Center                $1,200.00   Corporate Sponsorships
 Education Center
Movement Disorder Society           $2,500.00   Educational Grants
Movement Disorder Society          $10,000.00   Educational Grants
Movement Disorder Society          $25,000.00   Corporate Sponsorships
Movement Disorder Society          $25,000.00   Corporate Sponsorships
Movement Disorder Society          $15,000.00   Corporate Sponsorships
Movement Disorder Society         $208,750.00   Corporate Sponsorships
Movement Disorder Society          $50,000.00   Corporate Sponsorships
Multiple Myeloma Research          $25,000.00   Patient Support
 Foundation Inc.
Multiple Myeloma Research          $50,000.00   Patient Support
 Foundation Inc.
Multiple Myeloma Research          $10,000.00   Patient Support
 Foundation Inc.
Multiple Myeloma Research          $20,000.00   Patient Support
 Foundation Inc.
Multiple Myeloma Research          $25,000.00   Corporate Sponsorships
 Foundation Inc.
Multiple Myeloma Research          $55,000.00   Fellowships and
 Foundation Inc.                                 Scholarships
Multiple Myeloma Research          $20,000.00   Educational Grants
 Foundation Inc.
Multiple Myeloma Research          $20,000.00   Educational Grants
 Foundation Inc.
Multiple Myeloma Research          $75,000.00   Educational Grants
 Foundation Inc.
Multiple Myeloma Research          $50,000.00   Educational Grants
 Foundation Inc.
Multiple Myeloma Research          $75,000.00   Educational Grants
 Foundation Inc.
Musella Foundation for             $10,000.00   Corporate Sponsorships
 Brain Tumor Research and
 Information Inc.
Nami Oregon                         $2,250.00   Corporate Sponsorships
Nami Oregon                         $2,250.00   Corporate Sponsorships
Nami Tennessee                      $2,500.00   Corporate Sponsorships
National Academy of                $30,000.00   Corporate Sponsorships
 Dermatology Nurse
 Practitioners
National Academy of Science        $85,000.00   Corporate Sponsorships
National AIDS Treatment           $300,000.00   Charitable Donations
 Advocacy Project (NATAP)
National Alliance of               $20,000.00   Corporate Sponsorships
 Healthcare Purchaser
 Coalitions
National Alliance of State        $100,000.00   Corporate Sponsorships
 and Territorial Aids
 Directors
National Alliance of State         $50,000.00   Charitable Donations
 and Territorial Aids
 Directors
National Animal Interest           $15,000.00   Charitable Donations
 Alliance
National Associate of              $45,000.00   Educational Grants
 Managed Care Physician
National Associate of              $20,000.00   Educational Grants
 Managed Care Physician
National Associate of              $45,000.00   Educational Grants
 Managed Care Physician
National Association of               $300.00   Charitable Donations
 Area Agencies On Aging
 (N4a)
National Association of             $6,600.00   Corporate Sponsorships
 Community Health Centers
 Nachc
National Association of            $10,000.00   Charitable Donations
 School Nurses Inc.
National Brain Tumor                $5,700.00   Charitable Donations
 Society Inc.
National Brain Tumor               $25,000.00   Corporate Sponsorships
 Society Inc.
National Brain Tumor               $50,000.00   Charitable Donations
 Society Inc.
National Brain Tumor               $50,000.00   Educational Grants
 Society Inc.
National Brain Tumor               $50,000.00   Corporate Sponsorships
 Society Inc.
National Coalition for             $50,000.00   Corporate Sponsorships
 Cancer Survivorship
National Coalition for              $2,500.00   Corporate Sponsorships
 Cancer Survivorship
National Coalition for              $2,500.00   Corporate Sponsorships
 Cancer Survivorship
National Coalition for             $25,000.00   Corporate Sponsorships
 Cancer Survivorship
National Coalition for             $25,000.00   Corporate Sponsorships
 Cancer Survivorship
National Community                 $80,000.00   Corporate Sponsorships
 Dispensing Associate Ncoda
National Comprehensive             $15,000.00   Corporate Sponsorships
 Cancer Network
National Comprehensive             $15,000.00   Corporate Sponsorships
 Cancer Network
National Comprehensive             $40,000.00   Corporate Sponsorships
 Cancer Network
National Comprehensive             $30,000.00   Educational Grants
 Cancer Network
National Comprehensive             $60,000.00   Educational Grants
 Cancer Network
National Comprehensive             $75,000.00   Educational Grants
 Cancer Network
National Comprehensive              $5,000.00   Corporate Sponsorships
 Cancer Network
National Comprehensive             $25,000.00   Educational Grants
 Cancer Network
National Comprehensive             $50,000.00   Educational Grants
 Cancer Network
National Comprehensive             $55,000.00   Educational Grants
 Cancer Network
National Comprehensive             $40,000.00   Patient Support
 Cancer Network Foundation
National Comprehensive            $100,000.00   Fellowships and
 Cancer Network Foundation                       Scholarships
National Comprehensive             $40,000.00   Patient Support
 Cancer Network Foundation
National Comprehensive             $25,000.00   Patient Support
 Cancer Network Foundation
National Comprehensive             $40,000.00   Patient Support
 Cancer Network Foundation
National Comprehensive             $50,000.00   Charitable Donations
 Cancer Network Foundation
National Comprehensive            $100,000.00   Fellowships and
 Cancer Network Foundation                       Scholarships
National Eczema Association        $10,000.00   Corporate Sponsorships
National Health Council            $50,000.00   Corporate Sponsorships
National Minority Quality          $75,000.00   Corporate Sponsorships
 forum Inc.
National Minority Quality          $75,000.00   Corporate Sponsorships
 forum Inc.
National Multiple Sclerosis        $10,000.00   Corporate Sponsorships
 Society
National Pancreas                 $150,000.00   Educational Grants
 Foundation
National Pancreas                  $75,000.00   Corporate Sponsorships
 Foundation
National Pancreas                  $75,000.00   Charitable Donations
 Foundation
National Pancreas                  $70,000.00   Corporate Sponsorships
 Foundation
National Partnership for            $5,000.00   Corporate Sponsorships
 Women and Families Inc.
National Psoriasis                 $50,000.00   Fellowships and
 Foundation                                      Scholarships
National Psoriasis                 $15,000.00   Corporate Sponsorships
 Foundation
National Psoriasis                 $25,000.00   Corporate Sponsorships
 Foundation
National Psoriasis                 $50,000.00   Corporate Sponsorships
 Foundation
National Psoriasis                  $5,000.00   Corporate Sponsorships
 Foundation
National Psoriasis                 $50,000.00   Educational Grants
 Foundation
National Psoriasis                 $35,000.00   Corporate Sponsorships
 Foundation
National Psoriasis                 $25,000.00   Educational Grants
 Foundation
National Psoriasis                $150,000.00   Corporate Sponsorships
 Foundation
National Psoriasis                 $30,000.00   Corporate Sponsorships
 Foundation
National Psoriasis                 $15,000.00   Corporate Sponsorships
 Foundation
National Psoriasis                 $50,000.00   Corporate Sponsorships
 Foundation
National Psoriasis                 $75,000.00   Fellowships and
 Foundation                                      Scholarships
National Psoriasis                 $30,000.00   Corporate Sponsorships
 Foundation
National Psoriasis                 $40,000.00   Corporate Sponsorships
 Foundation
National Psoriasis                 $40,000.00   Corporate Sponsorships
 Foundation
National Society for               $55,000.00   Corporate Sponsorships
 Cutaneous Medicine
National Society for               $80,000.00   Corporate Sponsorships
 Cutaneous Medicine
National Society for              $225,000.00   Corporate Sponsorships
 Cutaneous Medicine
National Society for              $160,000.00   Corporate Sponsorships
 Cutaneous Medicine
New England Immunology              $2,500.00   Corporate Sponsorships
 Conference Inc.
New Jersey Academy of             ($7,440.00)   Educational Grants
 Family Physicians
New York Academy of Science         $3,500.00   Educational Grants
New York Academy of Science         $5,000.00   Educational Grants
New York Academy of Science         $5,000.00   Educational Grants
New York Academy of Science         $2,500.00   Educational Grants
New York Cancer Foundation         $10,000.00   Corporate Sponsorships
New York University School        ($5,000.00)   Educational Grants
 of Medicine
Nikki Mitchell Foundation           $7,500.00   Corporate Sponsorships
NL Communications Inc.             $35,000.00   Educational Grants
NL Communications Inc.             $75,000.00   Educational Grants
NL Communications Inc.             $25,000.00   Educational Grants
NL Communications Inc.            $225,000.00   Educational Grants
NL Communications Inc.             $25,000.00   Educational Grants
NL Communications Inc.             $55,000.00   Educational Grants
NL Communications Inc.             $30,000.00   Educational Grants
NL Communications Inc.             $85,000.00   Educational Grants
NL Communications Inc.             $35,000.00   Educational Grants
NL Communications Inc.             $25,000.00   Educational Grants
NL Communications Inc.             $75,000.00   Educational Grants
NL Communications Inc.             $45,000.00   Educational Grants
NL Communications Inc.             $75,000.00   Educational Grants
NL Communications Inc.             $20,000.00   Educational Grants
NL Communications Inc.             $30,000.00   Educational Grants
NL Communications Inc.             $50,000.00   Educational Grants
NL Communications Inc.             $25,000.00   Educational Grants
NL Communications Inc.             $60,000.00   Educational Grants
NL Communications Inc.            $125,000.00   Educational Grants
NL Communications Inc.            $145,000.00   Educational Grants
North American Center for         $375,000.00   Educational Grants
 Continuing Med Education
North American Society for          $5,000.00   Corporate Sponsorships
 Pediatric and Adolescent
 Gynecology
North American Society for         $25,000.00   Educational Grants
 Pediatric Gastroenterology
 Hepatology and Nutrition
North Carolina Academy of         $235,500.00   Educational Grants
 Family Physcians
North Carolina Academy of          $10,000.00   Corporate Sponsorships
 Family Physcians
North Carolina Oncology             $5,000.00   Corporate Sponsorships
 Management Society
North Carolina Society of           $5,000.00   Corporate Sponsorships
 Eye Physicians and
 Surgeons
North Dakota Pharmacists            $2,500.00   Corporate Sponsorships
 Association
Northeast Business Group On        $10,000.00   Corporate Sponsorships
 Health
Northeast Business Group On         $7,500.00   Corporate Sponsorships
 Health
Northeast Kidney Foundation         $5,000.00   Corporate Sponsorships
 Inc.
Northern California Society        $20,000.00   Corporate Sponsorships
 for Clinical
 Gastroenterology
Northwell Health                   $10,000.00   Corporate Sponsorships
Northwest Parkinsons                $5,000.00   Patient Support
 Foundation
Northwest Parkinsons                $5,000.00   Patient Support
 Foundation
Northwestern Univ                  $50,000.00   Fellowships and
                                                 Scholarships
Northwestern Univ                   $5,000.00   Corporate Sponsorships
Northwestern Univ                   $5,000.00   Educational Grants
Northwestern Univ                   $3,000.00   Educational Grants
Northwestern Univ                   $3,000.00   Fellowships and
                                                 Scholarships
Northwestern Univ                  $10,000.00   Corporate Sponsorships
Nutrition4kids, LLC                $75,000.00   Patient Support
Nutrition4kids, LLC               $100,000.00   Patient Support
NYU School of Medicine              $7,500.00   Educational Grants
NYU School of Medicine             $40,000.00   Fellowships and
                                                 Scholarships
NYU School of Medicine             $10,000.00   Educational Grants
 Cardiothoracic Surgery
NYU School of Medicine              $7,500.00   Educational Grants
 Cardiothoracic Surgery
Ochsner Clinic Foundation          $10,000.00   Corporate Sponsorships
Ocular Immunology and              $65,000.00   Corporate Sponsorships
 Uveitis Foundation
Ohio Association of                 $1,300.00   Corporate Sponsorships
 Community Health Centers
Ohio Association of                $10,000.00   Corporate Sponsorships
 Rheumatology
Ohio Gastroenterology               $5,000.00   Corporate Sponsorships
 Society
Ohio Gastroenterology               $3,000.00   Corporate Sponsorships
 Society
Ohio State Univ                     $3,500.00   Educational Grants
Omnia Education Inc.              $231,475.00   Educational Grants
Oncology Nursing Society           $38,500.00   Corporate Sponsorships
Oncology Nursing Society            $9,100.00   Corporate Sponsorships
Oregon Health and Science           $3,000.00   Patient Support
 Univ
Oregon Health and Science          $12,000.00   Corporate Sponsorships
 Univ
Oregon Health and Science          $10,000.00   Educational Grants
 Univ
Our Brain Bank                     $50,000.00   Corporate Sponsorships
Pacific Business Group On          $15,000.00   Corporate Sponsorships
 Health
Pacific Business Group On           $6,250.00   Corporate Sponsorships
 Health
Pacific Business Group On           $6,250.00   Corporate Sponsorships
 Health
Pacific Business Group On           $6,250.00   Corporate Sponsorships
 Health
Pacific Business Group On           $6,250.00   Corporate Sponsorships
 Health
Pacific Dermatologic               $20,000.00   Corporate Sponsorships
 Association
Pacific Dermatologic               $30,000.00   Corporate Sponsorships
 Association
Pack Center LLC                   $242,750.00   Patient Support
Pack Center LLC                   $200,000.00   Patient Support
Pack Center LLC                    $13,100.00   Educational Grants
Pack Center LLC                   $125,500.00   Educational Grants
Pack Center LLC                   $110,225.00   Educational Grants
Pack Center LLC                   $151,700.00   Educational Grants
Pancreatic Cancer Action           $50,000.00   Educational Grants
 Network
Para LA Naturaleza Inc.               $500.00   Charitable Donations
Park Nicollet Foundation            $1,000.00   Corporate Sponsorships
Park Nicollet Foundation            $1,000.00   Corporate Sponsorships
Parkinson Alliance                  $1,000.00   Corporate Sponsorships
Parkinson and Movement             $10,000.00   Patient Support
 Disorder Alliance
Parkinson and Movement             $15,000.00   Patient Support
 Disorder Alliance
Parkinson and Movement             $50,000.00   Patient Support
 Disorder Alliance
Parkinson and Movement            $100,000.00   Corporate Sponsorships
 Disorder Alliance
Parkinson and Movement             $15,000.00   Patient Support
 Disorder Alliance
Parkinson and Movement             $10,000.00   Educational Grants
 Disorder Alliance
Parkinson Association of            $1,000.00   Corporate Sponsorships
 Alabama
Parkinson Association of            $1,250.00   Corporate Sponsorships
 Greater Daytona Beach
 Pagdb
Parkinson Association of            $1,000.00   Corporate Sponsorships
 Northern California
Parkinson Association of            $1,000.00   Corporate Sponsorships
 The Carolinas
Parkinson Association of            $1,000.00   Corporate Sponsorships
 The Carolinas
Parkinson Council                  $25,000.00   Corporate Sponsorships
Parkinson Foundation of             $1,000.00   Corporate Sponsorships
 Oklahoma
Parkinson Foundation of The        $10,000.00   Patient Support
 National Capital Area
Parkinson Foundation of The        $10,000.00   Patient Support
 National Capital Area
Parkinson Foundation of The         $2,500.00   Corporate Sponsorships
 National Capital Area
Parkinson Foundation                $5,000.00   Corporate Sponsorships
 Western Pennsylvania
Parkinson Ntwrk of Arizona            $500.00   Corporate Sponsorships
Parkinson Support Center of        $10,000.00   Corporate Sponsorships
 Kentuciana
Parkinson Support Center of         $2,500.00   Corporate Sponsorships
 Kentuciana
Parkinson's Association of          $1,000.00   Corporate Sponsorships
 San Diego
Parkinson's Association of         $17,000.00   Corporate Sponsorships
 San Diego
Parkinsons Association of           $7,500.00   Patient Support
 The Rockies
Parkinsons Awareness                $1,250.00   Corporate Sponsorships
 Association of Central
 Indiana
Parkinsons Disease                  $2,500.00   Corporate Sponsorships
 Foundation
Parkinsons Disease                  $5,000.00   Corporate Sponsorships
 Foundation
Parkinsons Disease                 $25,000.00   Corporate Sponsorships
 Foundation
Parkinsons Disease                  $5,000.00   Corporate Sponsorships
 Foundation
Parkinsons Disease                $135,000.00   Corporate Sponsorships
 Foundation
Parkinsons Disease                  $2,500.00   Corporate Sponsorships
 Foundation
Parkinsons Disease                 $10,000.00   Corporate Sponsorships
 Foundation
Parkinsons Disease                  $4,500.00   Corporate Sponsorships
 Foundation
Parkinson's Nebraska                $1,000.00   Corporate Sponsorships
Parkinson's Nebraska                $1,000.00   Corporate Sponsorships
Parkinsons Unity Walk              $54,000.00   Corporate Sponsorships
Partnership for A Drug Free        $75,000.00   Charitable Donations
 America
Partnership for Cures              $60,000.00   Patient Support
Partnership for Quality Med         $1,000.00   Charitable Donations
 Donations Pqmd
Partnership for Quality Med         $5,000.00   Charitable Donations
 Donations Pqmd
Patient Access Network          $1,200,000.00   Charitable Donations
 Foundation
Patient Access Network         $12,007,000.00   Charitable Donations
 Foundation
Patient Access Network          $5,000,000.00   Charitable Donations
 Foundation
Patient Access Network         $10,000,000.00   Charitable Donations
 Foundation
Patient Access Network         $11,200,000.00   Charitable Donations
 Foundation
Patient Access Network         $11,022,000.00   Charitable Donations
 Foundation
Patient Access Network         $30,000,000.00   Charitable Donations
 Foundation
Patient Empowerment Ntwrk          $20,000.00   Patient Support
Patient Empowerment Ntwrk          $40,000.00   Patient Support
Patient Empowerment Ntwrk          $10,000.00   Patient Support
Patient Empowerment Ntwrk          $10,000.00   Patient Support
Patient Empowerment Ntwrk          $20,000.00   Patient Support
Patient Empowerment Ntwrk          $20,000.00   Patient Support
Patient Empowerment Ntwrk          $30,000.00   Patient Support
Patient Empowerment Ntwrk          $10,000.00   Charitable Donations
Patient Empowerment Ntwrk          $20,000.00   Patient Support
PD Gladiators                      $10,000.00   Corporate Sponsorships
PD Gladiators                      $10,000.00   Charitable Donations
Pediatric Specialists of            $2,500.00   Corporate Sponsorships
 Virginia LLC
Peerview Institute for              $5,000.00   Educational Grants
 Medical Education
Pennsylvania Academy of            $10,000.00   Corporate Sponsorships
 Dermatology and
 Dermatologic Surgry
Pennsylvania Prostate               $1,000.00   Corporate Sponsorships
 Cancer Coalition
Pennsylvania Society of            $10,000.00   Corporate Sponsorships
 Gastroenterology
Pennsylvania Society of             $5,000.00   Corporate Sponsorships
 Gastroenterology
People To People Health            $15,000.00   Charitable Donations
 Foundation
People To People Health            $20,000.00   Charitable Donations
 Foundation
Pharmacy Benefit Management         $7,500.00   Corporate Sponsorships
 Institute
Pharmacy Benefit Management         $5,500.00   Corporate Sponsorships
 Institute
Phoenix Obgyn Society               $2,000.00   Corporate Sponsorships
Phoenix Rheumatology               $10,000.00   Corporate Sponsorships
 Association
Phrmct Care Management             $95,000.00   Corporate Sponsorships
 Associate
Physicians Continuing              $42,000.00   Corporate Sponsorships
 Education
Physicians Education               $42,550.00   Educational Grants
 Resource LLC
Physicians Education               $50,000.00   Educational Grants
 Resource LLC
Physicians Education               $85,000.00   Educational Grants
 Resource LLC
Physicians Education              $100,000.00   Educational Grants
 Resource LLC
Physicians Education               $40,000.00   Educational Grants
 Resource LLC
Physicians Education               $50,000.00   Educational Grants
 Resource LLC
Physicians Education               $75,000.00   Educational Grants
 Resource LLC
Pinnacle Clinical Research          $5,000.00   Corporate Sponsorships
Pins for Parkinsons                   $500.00   Corporate Sponsorships
Platformq Health Education,       $125,000.00   Educational Grants
 LLC
Postgraduate Healthcare            $25,000.00   Educational Grants
 Education LLC
Postgraduate Institute for         $50,000.00   Educational Grants
 Medicine
Postgraduate Institute for        $350,000.00   Educational Grants
 Medicine
Presbyterian Healthcare             $5,000.00   Corporate Sponsorships
 Foundation
President and Fellows of           $12,000.00   Educational Grants
 Harvard College
President and Fellows of           $20,000.00   Corporate Sponsorships
 Harvard College
President and Fellows of           $30,000.00   Educational Grants
 Harvard College
President and Fellows of           $11,500.00   Educational Grants
 Harvard College
President and Fellows of            $3,000.00   Educational Grants
 Harvard College
President and Fellows of         ($18,400.00)   Educational Grants
 Harvard College
Prevent Cancer Foundation          $25,000.00   Corporate Sponsorships
Prevent Cancer Foundation         $100,000.00   Corporate Sponsorships
Prime Education Inc.              $120,000.00   Educational Grants
Prime Education Inc.              $225,000.00   Educational Grants
Prime Education Inc.              $150,000.00   Educational Grants
Prime Education Inc.              $199,725.00   Educational Grants
Prime Education Inc.              $200,000.00   Educational Grants
Prime Education Inc.              $200,000.00   Educational Grants
Prime Education Inc.              $295,217.00   Educational Grants
Prime Education Inc.               $93,930.00   Educational Grants
Prime Education Inc.              $200,000.00   Educational Grants
Prime Education Inc.              $274,830.00   Educational Grants
Prime Education Inc.              $200,000.00   Educational Grants
Prime Education Inc.              $200,000.00   Educational Grants
Prime Oncology Inc.               $150,000.00   Educational Grants
Prime Oncology Inc.                $85,000.00   Educational Grants
Prime Oncology Inc.                $81,260.00   Educational Grants
Prime Oncology Inc.                $86,320.00   Educational Grants
Prime Oncology Inc.               $222,410.00   Educational Grants
Prime Oncology Inc.                $75,000.00   Educational Grants
Prime Oncology Inc.                $75,000.00   Educational Grants
Prime Oncology LLC               ($21,072.00)   Educational Grants
Primo Education LLC                $15,000.00   Corporate Sponsorships
Project Inform                     $50,000.00   Charitable Donations
Project Inform                     $10,000.00   Corporate Sponsorships
Projects in Knowledge Inc.        $125,000.00   Educational Grants
Projects in Knowledge Inc.         $78,000.00   Educational Grants
Promis Health Organization         $10,000.00   Educational Grants
Prostate Cancer Foundation          $1,400.00   Corporate Sponsorships
 Chicago
Prostate Cancer                     $5,000.00   Charitable Donations
 International
Prostate Cancer Research           $15,000.00   Corporate Sponsorships
 Instutute
Prostaware                          $1,500.00   Corporate Sponsorships
Prostaware                          $1,500.00   Corporate Sponsorships
Providence Health and              $20,000.00   Patient Support
 Services Southern
 California
Psoriasis and Psoriatic           $100,000.00   Corporate Sponsorships
 Arthritis Clinics
 Multicenter Advancement
 Network
Puerto Rico Associate of          ($1,088.60)   Educational Grants
 Gastroenterology
Puerto Rico Associate of            $5,000.00   Corporate Sponsorships
 Gastroenterology
Puerto Rico Associate of           $30,000.00   Corporate Sponsorships
 Gastroenterology
Puerto Rico Associate of           $20,000.00   Educational Grants
 Gastroenterology
Puerto Rico Nephrology              $3,500.00   Corporate Sponsorships
 Society Inc.
Puerto Rico Obstetrician            $1,400.00   Corporate Sponsorships
 and Gyn Inc.
Puerto Rico Obstetrician           $17,000.00   Corporate Sponsorships
 and Gyn Inc.
Puerto Rico Obstetrician            $5,000.00   Corporate Sponsorships
 and Gyn Inc.
Purdue Univ College of             $50,000.00   Educational Grants
 Pharmacy
Purdue Univ College of            $200,000.00   Educational Grants
 Pharmacy
Purdue Univ College of           ($18,852.35)   Educational Grants
 Pharmacy
Purdue Univ College of            $150,000.00   Educational Grants
 Pharmacy
Randolph College                    $1,000.00   Charitable Donations
Regents of The Univ of              $5,000.00   Educational Grants
 California
Regents of The Univ of             $40,000.00   Fellowships and
 California                                      Scholarships
Regents of The Univ of             $40,000.00   Fellowships and
 California                                      Scholarships
Regents of The Univ of             $17,612.00   Fellowships and
 California                                      Scholarships
Regents of The Univ of              $2,500.00   Patient Support
 California
Regents of The Univ of             $55,000.00   Fellowships and
 California                                      Scholarships
Regents of The Univ of             $40,000.00   Fellowships and
 California                                      Scholarships
Regents of The Univ of             $10,000.00   Educational Grants
 California
Regents of The Univ of             $25,000.00   Corporate Sponsorships
 California
Regents of The Univ of             $10,000.00   Educational Grants
 California
Regents of The Univ of             $20,000.00   Corporate Sponsorships
 Michigan
Regents of The Univ of              $1,000.00   Educational Grants
 Michigan
Regents of The Univ of              $1,000.00   Corporate Sponsorships
 Michigan
Respiratory Health                  $4,050.00   Corporate Sponsorships
 Association of
 Metropolitan Chicago
Respiratory Health                  $4,050.00   Corporate Sponsorships
 Association of
 Metropolitan Chicago
Respiratory Health                  $4,050.00   Corporate Sponsorships
 Association of
 Metropolitan Chicago
Revolutionizing Atopic             $35,000.00   Corporate Sponsorships
 Dermatitis
Rheumatology Association of        $10,000.00   Corporate Sponsorships
 Minnesota and The Dakotas
Rheumatology Nurses Society        $87,500.00   Educational Grants
Rheumlgy Alliance of               $25,000.00   Corporate Sponsorships
 Louisiana
Rheumnow                          $105,000.00   Corporate Sponsorships
Rheumnow                           $60,000.00   Corporate Sponsorships
Richmond County Medical             $2,500.00   Corporate Sponsorships
 Society
Riverside Medical Clinic           $10,000.00   Patient Support
 Charitable Foundation
Rocky Mountain MS Center            $5,000.00   Patient Support
Ronald Mcdonald House          $60,000,000.00   Charitable Donations
 Charities, Inc.
Ronald Mcdonald House          $20,000,000.00   Charitable Donations
 Charities, Inc.
Ronald Mcdonald House          $20,000,000.00   Charitable Donations
 Charities, Inc.
Roswell Park Alliance               $5,000.00   Educational Grants
 Foundation
Rotary Club of Downtown             $1,000.00   Corporate Sponsorships
 Macon
Runx1 Foundation                    $2,500.00   Educational Grants
Rush University Medical            $65,000.00   Educational Grants
 Center
Rush University Medical            $75,000.00   Educational Grants
 Center
Rush University Medical             $5,000.00   Charitable Donations
 Center
Rush University Medical               $300.00   Charitable Donations
 Center
Rush University Medical            $95,000.00   Educational Grants
 Center
Rush University Medical            $85,000.00   Educational Grants
 Center
Rush University Medical           $113,550.00   Educational Grants
 Center
Rush University Medical            $75,000.00   Educational Grants
 Center
Safety Pharmacology Society         $5,000.00   Educational Grants
Samaritan Daytop Village            $2,500.00   Corporate Sponsorships
San Francisco Aids                 $10,000.00   Charitable Donations
 Foundation
San Francisco Public Center       $100,000.00   Charitable Donations
 Foundation
San Francisco Retina                $5,000.00   Educational Grants
 Foundation
San Juan Bautista Medical          $40,000.00   Fellowships and
 Center                                          Scholarships
Scripps Health                     $10,000.00   Corporate Sponsorships
Scripps Health                     $66,500.00   Corporate Sponsorships
Scripps Health                     $20,000.00   Educational Grants
Seattle Science Foundation          $8,500.00   Educational Grants
Shanti                             $10,000.00   Charitable Donations
Share                               $7,500.00   Charitable Donations
Sociedad Dermatologica de          $20,000.00   Corporate Sponsorships
 Puerto Rico
Sociedad Dermatologica de          $15,000.00   Corporate Sponsorships
 Puerto Rico
Sociedad PR Endocrinologia         $15,000.00   Corporate Sponsorships
 y Diabetologia
Sociedad Puertorriquena             $5,000.00   Corporate Sponsorships
 Pediatria
Society for Clinical Trials         $2,000.00   Corporate Sponsorships
Society for Leukocyte               $2,000.00   Educational Grants
 Biology
Society for Neuro-Oncology         $50,000.00   Corporate Sponsorships
Society for Neuro-Oncology         $20,000.00   Educational Grants
Society for Neuro-Oncology         $39,140.00   Educational Grants
Society for Neuro-Oncology         $58,000.00   Educational Grants
Society for Neuro-Oncology         $50,000.00   Corporate Sponsorships
Society for Physician              $10,000.00   Charitable Donations
 Assistants in Pediatrics
Society for Womens Health          $25,000.00   Corporate Sponsorships
 Research
Society of Dermatology             $50,000.00   Corporate Sponsorships
 Physician Assistants
Society of Dermatology             $40,000.00   Corporate Sponsorships
 Physician Assistants
Society of Gynecologic             $27,500.00   Corporate Sponsorships
 Surgeons
Society of Investigative           $30,000.00   Educational Grants
 Dermatology
Socty for Gynecologic              $10,000.00   Corporate Sponsorships
 Investigation
Socty for Immunotherapy of         $50,000.00   Corporate Sponsorships
 Cancer
Socty for Immunotherapy of          $5,000.00   Educational Grants
 Cancer
Socty for Immunotherapy of         $25,000.00   Corporate Sponsorships
 Cancer
South Carolina Alliance of          $6,000.00   Corporate Sponsorships
 Health Plans
South Dakota Parkinson              $2,500.00   Corporate Sponsorships
 Foundation
South Dakota Parkinson              $1,000.00   Corporate Sponsorships
 Foundation
South Sound Care Foundation         $3,250.00   Corporate Sponsorships
Southern California Society       $100,000.00   Corporate Sponsorships
 of Gastroenterology
Spondylitis Association of         $20,000.00   Patient Support
 America
Spondylitis Association of         $40,000.00   Patient Support
 America
Spondylitis Association of         $17,750.00   Educational Grants
 America
Spondyloarthritis Research         $70,000.00   Corporate Sponsorships
 and Treatment Network
 Spartan
St. Barnabas Hospital               $1,300.00   Fellowships and
                                                 Scholarships
St. Jude Childrens Research    $30,000,000.00   Charitable Donations
 Hospital
St. Jude Childrens Research    $20,000,000.00   Charitable Donations
 Hospital
St. Lukes Hospital                  $2,500.00   Corporate Sponsorships
State of West Virginia              $2,500.00   Corporate Sponsorships
 Rheumatology Society
Super Jake Foundation The          $25,000.00   Charitable Donations
Susan G Komen Colorado              $5,000.00   Corporate Sponsorships
Susan G Komen Colorado              $5,000.00   Corporate Sponsorships
Talem Health Inc.                  $95,000.00   Educational Grants
Talem Health Inc.                 $235,820.00   Educational Grants
Tarsus Cardiology Inc. Dba         $35,000.00   Corporate Sponsorships
 South Beach Symposium
Texas Academy of Family             $2,500.00   Corporate Sponsorships
 Physicians
Texas Academy of Family             $2,500.00   Corporate Sponsorships
 Physicians Foundation
Texas Healthcare and                $5,000.00   Corporate Sponsorships
 Bioscience
Texas Indo-American                 $5,000.00   Corporate Sponsorships
 Physicians Society
Texas Medical Association           $5,000.00   Corporate Sponsorships
Texas Osteopathic Medical           $3,000.00   Corporate Sponsorships
 Association Foundation
Thomas Jefferson University         $5,000.00   Educational Grants
Thomas Jefferson University         $3,000.00   Corporate Sponsorships
Thomas Jefferson University         $3,000.00   Corporate Sponsorships
Thomas Jefferson University         $3,000.00   Corporate Sponsorships
Thomas Jefferson University         $5,000.00   Corporate Sponsorships
Translational Research in           $5,000.00   Educational Grants
 Oncology US Inc.
Trinity International               $1,000.00   Charitable Donations
 College
Tufts Medical Center              ($1,190.13)   Educational Grants
Tufts Medical Center                ($513.14)   Educational Grants
UC Regents Maxillofacial           $10,000.00   Educational Grants
 Prosthetics Clinic
UC Regents Maxillofacial           $40,000.00   Fellowships and
 Prosthetics Clinic                              Scholarships
UC Regents Maxillofacial           $15,000.00   Educational Grants
 Prosthetics Clinic
Ultimate Medical Academy          ($4,043.06)   Educational Grants
 LLC
Ultimate Medical Academy          $174,700.00   Educational Grants
 LLC
Ultimate Medical Academy           $50,000.00   Educational Grants
 LLC
Ultimate Medical Academy          ($2,344.80)   Educational Grants
 LLC
Ultimate Medical Academy          $150,000.00   Educational Grants
 LLC
Ultimate Medical Academy          $100,000.00   Educational Grants
 LLC
Ultimate Medical Academy          $125,000.00   Educational Grants
 LLC
Ultimate Medical Academy          ($5,138.86)   Educational Grants
 LLC
Ultimate Medical Academy          ($3,284.05)   Educational Grants
 LLC
Ultimate Medical Academy          ($2,134.44)   Educational Grants
 LLC
Ultimate Medical Academy          ($9,000.00)   Educational Grants
 LLC
Ultimate Medical Academy            ($885.32)   Educational Grants
 LLC
Ultimate Medical Academy          $245,000.00   Educational Grants
 LLC
Ultimate Medical Academy           $95,000.00   Educational Grants
 LLC
Ultimate Medical Academy          $500,000.00   Educational Grants
 LLC
Ultimate Medical Academy          $349,450.00   Educational Grants
 LLC
UMA Education Inc. Dba             $50,000.00   Educational Grants
 Global Education Group
UMA Education Inc. Dba            $375,000.00   Educational Grants
 Global Education Group
UMA Education Inc. Dba            $225,000.00   Educational Grants
 Global Education Group
UMA Education Inc. Dba             $43,358.00   Educational Grants
 Global Education Group
UMA Education Inc. Dba            $163,000.00   Educational Grants
 Global Education Group
UMA Education Inc. Dba            $166,000.00   Educational Grants
 Global Education Group
UMA Education Inc. Dba             $10,000.00   Educational Grants
 Global Education Group
UMASS Memorial Foundation           $2,500.00   Corporate Sponsorships
 Inc.
United Medical Center               $2,280.00   Educational Grants
United Rheumatology               $225,000.00   Corporate Sponsorships
United Spinal Association          $12,500.00   Corporate Sponsorships
 Inc.
United Spinal Association          $12,500.00   Corporate Sponsorships
 Inc.
United States Adult Cystic          $5,000.00   Patient Support
 Fibrosis Association Inc.
United States and Canadian         $30,000.00   Corporate Sponsorships
 Academy of Pathology
United States Renal Care           $20,000.00   Corporate Sponsorships
 Inc.
Unity Health Care, Inc.             $7,500.00   Corporate Sponsorships
Univ Connecticut                  ($2,054.94)   Educational Grants
 Dermatology
Univ Connecticut                   $40,000.00   Fellowships and
 Dermatology                                     Scholarships
Univ Health Service at             $20,000.00   Educational Grants
 Stony Point Inc.
Univ Health Service at            $120,000.00   Corporate Sponsorships
 Stony Point Inc.
Univ Health Service at            $120,000.00   Corporate Sponsorships
 Stony Point Inc.
Univ of Chicago                     $8,000.00   Educational Grants
Univ of Chicago                    $50,000.00   Patient Support
Univ of Chicago                    $10,000.00   Educational Grants
Univ of Chicago                    $15,000.00   Educational Grants
Univ of Chicago                    $25,000.00   Educational Grants
Univ of Chicago                   ($2,097.00)   Educational Grants
Univ of Chicago                   $125,000.00   Educational Grants
Univ of Chicago                     $5,000.00   Corporate Sponsorships
Univ of Chicago                    $10,000.00   Corporate Sponsorships
Univ of Chicago                     $5,000.00   Educational Grants
Univ of Chicago                     $5,000.00   Corporate Sponsorships
Univ of Chicago                    $20,000.00   Corporate Sponsorships
Univ of Chicago                    $18,000.00   Educational Grants
Univ of Chicago                   ($7,232.53)   Educational Grants
Univ of Chicago                     $1,000.00   Charitable Donations
Univ of Chicago                    $10,000.00   Educational Grants
Univ of Chicago                    $45,000.00   Educational Grants
Univ of Chicago                    $10,000.00   Educational Grants
Univ of Cincinnati               ($68,461.18)   Educational Grants
Univ of Cincinnati                 $25,000.00   Corporate Sponsorships
Univ of Cincinnati                 $60,000.00   Educational Grants
Univ of Cincinnati                 $60,000.00   Educational Grants
Univ of Cincinnati                 $75,000.00   Educational Grants
Univ of Colorado Denver            $20,000.00   Fellowships and
 School of Medicine                              Scholarships
Univ of Connecticut Health         $12,000.00   Fellowships and
 Center, John Dempsey                            Scholarships
 Hospital
Univ of Florida Foundation         $60,000.00   Fellowships and
                                                 Scholarships
Univ of Illinois Foundation         $1,000.00   Charitable Donations
Univ of Louisville                 $15,000.00   Corporate Sponsorships
Univ of Louisville Research        $60,000.00   Educational Grants
 Foundation
Univ of Louisville Research        $50,000.00   Educational Grants
 Foundation
Univ of Louisville Research        $60,000.00   Educational Grants
 Foundation
Univ of Maryland Baltimore         $10,000.00   Patient Support
 Foundation Inc.
Univ of Maryland Baltimore          $5,000.00   Educational Grants
 Foundation Inc.
Univ of Massachusetts Med           $2,500.00   Corporate Sponsorships
 School
Univ of Miami                      $20,000.00   Corporate Sponsorships
Univ of Miami                      $40,000.00   Fellowships and
                                                 Scholarships
Univ of Miami                      $10,000.00   Corporate Sponsorships
Univ of Minnesota Regents           $2,000.00   Educational Grants
Univ of Nebraska Med Center       $100,000.00   Corporate Sponsorships
Univ of Nebraska Med Center        $50,000.00   Educational Grants
Univ of Nebraska Med Center        $35,000.00   Educational Grants
Univ of Nebraska Med Center       $150,000.00   Educational Grants
Univ of Nebraska Med Center       $125,000.00   Educational Grants
Univ of Nebraska Med Center       $128,860.00   Educational Grants
Univ of Nebraska Med Center           $600.00   Corporate Sponsorships
Univ of Nebraska Med Center        $10,000.00   Corporate Sponsorships
Univ of Nebraska Med Center        $25,000.00   Corporate Sponsorships
Univ of Nebraska Med Center        $30,000.00   Educational Grants
Univ of Nebraska Med Center         $7,500.00   Educational Grants
Univ of New Mexico Health          $10,000.00   Educational Grants
 Science Center Dept of
 Pediatrics Neonatology
 Division
Univ of Pittsburgh                 $15,000.00   Educational Grants
Univ of Pittsburgh                  $2,200.00   Educational Grants
Univ of Pittsburgh                 $20,000.00   Educational Grants
Univ of South Florida Board        $37,500.00   Fellowships and
 of Trustees                                     Scholarships
Univ of South Florida              $25,000.00   Educational Grants
 Health Professions
 Conferencing Corp
Univ of Southern California         $1,500.00   Educational Grants
Univ of Southern California        $25,000.00   Educational Grants
Univ of Southern California         $7,097.77   Fellowships and
                                                 Scholarships
Univ of Southern California        $81,500.00   Fellowships and
                                                 Scholarships
Univ of Texas at Austin             $5,000.00   Educational Grants
Univ of Texas Health               $16,032.00   Corporate Sponsorships
 Science Center at San
 Antonio
Univ of Texas Health               $75,000.00   Educational Grants
 Science Center at San
 Antonio
Univ of Toledo                      $2,000.00   Patient Support
Univ of Utah                       $40,000.00   Fellowships and
                                                 Scholarships
Univ of Wisconsin--Madison          $1,500.00   Educational Grants
Univeristy of Chicago              $15,000.00   Charitable Donations
 Cancer Research Foundation
Universidad Central Del           ($2,283.00)   Educational Grants
 Caribe School of Medicine
Universidad DE Puerto Rico         $30,000.00   Fellowships and
                                                 Scholarships
Universidad DE Puerto Rico         $59,783.50   Corporate Sponsorships
Universidad DE Puerto Rico         $30,000.00   Fellowships and
                                                 Scholarships
University Health Services         $75,000.00   Educational Grants
University Health Services          $5,000.00   Educational Grants
University Health Services         $25,000.00   Educational Grants
University of Alabama at           $40,000.00   Fellowships and
 Birmingham Hospital                             Scholarships
University of California           $40,000.00   Fellowships and
 Irvine                                          Scholarships
University of California            $6,000.00   Corporate Sponsorships
 San Francisco Foundation
University of Illinois--           $15,821.60   Fellowships and
 Office of Business and                          Scholarships
 Financial Services
University of Illinois--           $75,138.40   Fellowships and
 Office of Business and                          Scholarships
 Financial Services
University of North                $40,000.00   Fellowships and
 Carolina at Chapel Hill                         Scholarships
University of North                 $1,000.00   Charitable Donations
 Carolina at Chapel Hill
University of Rochester             $5,000.00   Educational Grants
University of South Florida       ($9,615.55)   Educational Grants
 Foundation
University of Texas                $55,000.00   Fellowships and
 Southwestern Medical                            Scholarships
 Center
University of Texas                $75,000.00   Fellowships and
 Southwestern Medical                            Scholarships
 Center
University of Washington           $40,000.00   Fellowships and
 Medical Center                                  Scholarships
University of Wisconsin LA          $1,000.00   Charitable Donations
 Crosse Foundation Inc.
Urogpo, LLC                        $35,000.00   Corporate Sponsorships
Urological Association of          $10,000.00   Corporate Sponsorships
 Physician Assistants
Urology Center of Colorado         $10,000.00   Corporate Sponsorships
 Foundation
US Too International                $1,500.00   Corporate Sponsorships
US Too International               $25,750.00   Corporate Sponsorships
Vanderbilt Univ By and            $190,000.00   Educational Grants
 Through Its Medical Center
Vanderbilt Univ By and             $10,000.00   Educational Grants
 Through Its Medical Center
Vanderbilt Univ By and              $5,000.00   Educational Grants
 Through Its Medical Center
Vanderbilt Urology Society          $3,000.00   Corporate Sponsorships
Veritas Meeting Solutions           $4,500.00   Corporate Sponsorships
VHA Inc.                           $35,000.00   Corporate Sponsorships
Vida Global Foundation              $1,500.00   Corporate Sponsorships
Vietnamese American                 $3,000.00   Corporate Sponsorships
 Healthcare Professionals
 Association of Georgia
Vindico Med Education              $50,000.00   Educational Grants
Vindico Med Education             $200,000.00   Educational Grants
Vindico Med Education              $50,000.00   Educational Grants
Vindico Med Education              $75,000.00   Educational Grants
Vindico Med Education              $50,000.00   Educational Grants
Vindico Med Education              $49,000.00   Educational Grants
Vindico Med Education              $50,000.00   Educational Grants
Vindico Med Education              $50,000.00   Educational Grants
Virginia Academy of                 $1,750.00   Corporate Sponsorships
 Physician Assistants
Virginia Commonwealth               $7,500.00   Corporate Sponsorships
 University School of
 Medicine
Virginia Council of Nurse           $1,493.94   Corporate Sponsorships
 Practitioners
Wake Forest Univ                   $40,000.00   Fellowships and
                                                 Scholarships
Wall Las Memorias                  $10,000.00   Corporate Sponsorships
Wartburg College                    $1,000.00   Charitable Donations
Washington International            $2,500.00   Corporate Sponsorships
 Trade Foundation
Washington International            $2,500.00   Corporate Sponsorships
 Trade Foundation
Washington International            $2,500.00   Corporate Sponsorships
 Trade Foundation
Washington International            $2,500.00   Corporate Sponsorships
 Trade Foundation
Washington Univ in St Louis         ($263.21)   Fellowships and
                                                 Scholarships
Washington Univ in St Louis         $6,000.00   Educational Grants
Washington Univ in St Louis         $1,500.00   Corporate Sponsorships
Washington Univ in St Louis         $1,600.00   Fellowships and
                                                 Scholarships
Washington Univ in St Louis      ($17,777.79)   Educational Grants
We Care in Inflammatory            $25,000.00   Charitable Donations
 Bowel Disease
WebMD Global LLC                   $90,000.00   Educational Grants
WebMD Global LLC                  $209,983.00   Educational Grants
WebMD Global LLC                  $209,983.00   Educational Grants
WebMD Global LLC                  $209,983.00   Educational Grants
WebMD Global LLC                   $50,000.00   Educational Grants
WebMD Global LLC                   $63,500.00   Educational Grants
WebMD Global LLC                   $81,500.00   Educational Grants
WebMD Global LLC                   $95,000.00   Educational Grants
WebMD Global LLC                  $348,000.00   Educational Grants
WebMD Global LLC                  $151,000.00   Educational Grants
WebMD Global LLC                  $172,000.00   Educational Grants
WebMD Global LLC                  $200,000.00   Educational Grants
WebMD Global LLC                   $75,000.00   Educational Grants
WebMD Global LLC                  ($1,500.00)   Educational Grants
WebMD Global LLC                  ($1,142.14)   Educational Grants
WebMD Global LLC                  $100,000.00   Educational Grants
WebMD Global LLC                   $65,000.00   Educational Grants
WebMD Global LLC                  $182,500.00   Educational Grants
WebMD Global LLC                  $150,000.00   Educational Grants
WebMD Global LLC                   $75,000.00   Educational Grants
WebMD Global LLC                  $350,000.00   Educational Grants
WebMD Global LLC                  $100,000.00   Educational Grants
WebMD Global LLC                  $113,500.00   Educational Grants
WebMD Global LLC                  $200,000.00   Educational Grants
WebMD Global LLC                  $227,000.00   Educational Grants
WebMD Global LLC                  $150,000.00   Educational Grants
WebMD Global LLC                  $350,000.00   Educational Grants
WebMD Global LLC                  $120,000.00   Educational Grants
WebMD Global LLC                  $136,150.00   Educational Grants
WebMD Global LLC                  $215,000.00   Educational Grants
WebMD Global LLC                  $319,770.00   Educational Grants
West Virginia Community             $5,000.00   Corporate Sponsorships
 Voices
Wisconsin Collaborative for         $3,750.00   Corporate Sponsorships
 Healthcare Quality
Wisconsin Rheumatology             $10,000.00   Corporate Sponsorships
 Association
Wisconsin Rheumatology             $10,000.00   Corporate Sponsorships
 Association
Wisconsin Section American          $2,000.00   Corporate Sponsorships
 Congress Obstetrics and
 Gynecologist Acog
Women in Government                 $2,500.00   Corporate Sponsorships
 Foundation Ltd
Women in Government                 $2,500.00   Corporate Sponsorships
 Foundation Ltd
Women in Government                 $5,000.00   Corporate Sponsorships
 Foundation Ltd
Women in Government                 $5,000.00   Corporate Sponsorships
 Foundation Ltd
Women in Government                 $7,500.00   Corporate Sponsorships
 Foundation Ltd
Women in Government                 $7,500.00   Corporate Sponsorships
 Foundation Ltd
Women in Government                 $5,000.00   Corporate Sponsorships
 Foundation Ltd
Women in Government                 $5,000.00   Corporate Sponsorships
 Foundation Ltd
Women in Government                 $5,000.00   Corporate Sponsorships
 Foundation Ltd
Women in Government                 $5,000.00   Corporate Sponsorships
 Foundation Ltd
Women in Government                $10,000.00   Corporate Sponsorships
 Foundation Ltd
Women in Government                $10,000.00   Corporate Sponsorships
 Foundation Ltd
Women in Government                 $2,500.00   Corporate Sponsorships
 Foundation Ltd
Women in Government                 $2,500.00   Corporate Sponsorships
 Foundation Ltd
Women in Government                 $2,500.00   Corporate Sponsorships
 Foundation Ltd
Women in Government                 $5,000.00   Corporate Sponsorships
 Foundation Ltd
Women in Government                 $7,000.00   Corporate Sponsorships
 Foundation Ltd
Women in Government                 $2,500.00   Corporate Sponsorships
 Foundation Ltd
Women in Government                $10,000.00   Corporate Sponsorships
 Foundation Ltd
World Parkinson Coalition          $50,000.00   Fellowships and
 Inc.                                            Scholarships
Worldwide Endomarch                 $5,000.00   Corporate Sponsorships
Worldwide Endomarch                 $3,000.00   Corporate Sponsorships
Yale Univ                           $5,000.00   Educational Grants
Zebrafish Disease Models            $5,000.00   Educational Grants
 Society
Zero The Project To End            $15,000.00   Corporate Sponsorships
 Prostate Cancer
Zero The Project To End           $270,000.00   Corporate Sponsorships
 Prostate Cancer
Zero The Project To End            $10,000.00   Corporate Sponsorships
 Prostate Cancer
Zero The Project To End            $12,000.00   Corporate Sponsorships
 Prostate Cancer
Zero The Project To End           $270,000.00   Corporate Sponsorships
 Prostate Cancer
------------------------------------------------------------------------


                                                                        Exhibit 2
--------------------------------------------------------------------------------------------------------------------------------------------------------
                      Organization Legal Name                              2014             2015             2016             2017             2018
--------------------------------------------------------------------------------------------------------------------------------------------------------
ALBERT B. SABIN VACCINE INSTITUTE, INC.                                   203,302.00                        835,251.00
--------------------------------------------------------------------------------------------------------------------------------------------------------
ALS THERAPY DEVELOPMENT FOUNDATION INC.                                                      5,159.91
--------------------------------------------------------------------------------------------------------------------------------------------------------
ALZHEIMER'S DISEASE AND RELATED DISORDERS ASSOCIATION, INC.                                                  10,000.00        10,000.00
--------------------------------------------------------------------------------------------------------------------------------------------------------
AMERICAN CANCER SOCIETY, INC.                                                                                 1,000.00
--------------------------------------------------------------------------------------------------------------------------------------------------------
AMERICAN RED CROSS                                                         50,000.00        20,000.00        80,000.00     1,425,000.00       775,000.00
--------------------------------------------------------------------------------------------------------------------------------------------------------
AMERICARES FOUNDATION, INC.                                               100,000.00        50,000.00        25,000.00       250,000.00       400,000.00
--------------------------------------------------------------------------------------------------------------------------------------------------------
APNA GHAR, INC. (OUR HOME)                                                                                                                     50,000.00
--------------------------------------------------------------------------------------------------------------------------------------------------------
ASIAN UNIVERSITY FOR WOMEN SUPPORT FOUNDATION                              50,000.00        50,000.00        50,000.00        50,000.00        50,000.00
--------------------------------------------------------------------------------------------------------------------------------------------------------
ASTRAEA FOUNDATION, INC.                                                                                                                       75,000.00
--------------------------------------------------------------------------------------------------------------------------------------------------------
BAYLOR COLLEGE OF MEDICINE INTERNATIONAL PEDIATRIC AIDS INITIATIVE      2,220,337.00     2,477,111.00     1,660,000.00     1,610,000.00     1,610,000.00
--------------------------------------------------------------------------------------------------------------------------------------------------------
BEACON PLACE NFP                                                                           100,000.00       100,000.00       125,000.00       150,000.00
--------------------------------------------------------------------------------------------------------------------------------------------------------
BERNARD P. FLORIANI FOUNDATION                                                              50,000.00        75,000.00       110,000.00       420,000.00
--------------------------------------------------------------------------------------------------------------------------------------------------------
BIG BROTHERS BIG SISTERS OF METROPOLITAN CHICAGO                                                                                               40,000.00
--------------------------------------------------------------------------------------------------------------------------------------------------------
BOYS AND GIRLS CLUB OF LAKE COUNTY                                                          10,000.00        10,000.00        10,000.00        25,000.00
--------------------------------------------------------------------------------------------------------------------------------------------------------
CARING AMBASSADORS PROGRAM, INC.                                          253,282.00
--------------------------------------------------------------------------------------------------------------------------------------------------------
CASA LAKE COUNTY                                                                            25,000.00        25,000.00        25,000.00        25,000.00
--------------------------------------------------------------------------------------------------------------------------------------------------------
CATALYSIS LLC                                                                                                                                          -
--------------------------------------------------------------------------------------------------------------------------------------------------------
CENTER FOR NEIGHBORHOOD ENTERPRISE                                                                           50,000.00
--------------------------------------------------------------------------------------------------------------------------------------------------------
CENTRAIDE OF GREATER MONTREAL (Matching Grants--Canada)                                                      11,000.00        11,000.00        19,600.00
--------------------------------------------------------------------------------------------------------------------------------------------------------
CHICAGO CARES INC.                                                                         314,504.00        18,000.00        15,000.00
--------------------------------------------------------------------------------------------------------------------------------------------------------
CHICAGO HORTICULTURAL SOCIETY                                                                                                                  50,000.00
--------------------------------------------------------------------------------------------------------------------------------------------------------
CHICAGO HOUSE AND SOCIAL SERVICE AGENCY                                                                                                        25,000.00
--------------------------------------------------------------------------------------------------------------------------------------------------------
CHICAGO TOOLBANK                                                                                                               5,000.00
--------------------------------------------------------------------------------------------------------------------------------------------------------
CHINESE AMERICAN SERVICE LEAGUE                                                                                                                50,000.00
--------------------------------------------------------------------------------------------------------------------------------------------------------
CHOCOLATE CHIPS ASSOCIATION                                                                                                                    10,000.00
--------------------------------------------------------------------------------------------------------------------------------------------------------
CITY OF NORTH CHICAGO                                                                                         5,000.00
--------------------------------------------------------------------------------------------------------------------------------------------------------
COMMUNITY ACTION PARTNERSHIP OF LAKE COUNTY                                                                 150,400.00       141,875.00
--------------------------------------------------------------------------------------------------------------------------------------------------------
CRADLES TO CRAYONS, INC.                                                                                                                      515,000.00
--------------------------------------------------------------------------------------------------------------------------------------------------------
CRISTO REY ST. MARTIN COLLEGE PREP                                                                                                             50,000.00
--------------------------------------------------------------------------------------------------------------------------------------------------------
DAVIS PHINNEY FOUNDATION                                                                                        120.00
--------------------------------------------------------------------------------------------------------------------------------------------------------
IDIRECT RELIEF                                                          1,865,000.00     1,941,111.00     1,325,000.00     2,115,000.00       850,000.00
--------------------------------------------------------------------------------------------------------------------------------------------------------
DRESS FOR SUCCESS WORLDWIDECENTRAL                                                                                                             90,000.00
--------------------------------------------------------------------------------------------------------------------------------------------------------
ERIE FAMILY HEALTH CENTER, INC.                                           100,000.00        55,000.00        50,000.00        50,000.00        50,000.00
--------------------------------------------------------------------------------------------------------------------------------------------------------
FAMILY REACH FOUNDATION                                                    100,00.00       300,000.00       320,000.00       300,000.00       300,000.00
--------------------------------------------------------------------------------------------------------------------------------------------------------
FEEDING AMERICA                                                                                                              225,000.00        25,000.00
--------------------------------------------------------------------------------------------------------------------------------------------------------
FIELD MUSEUM OF NATURAL HISTORY                                                                                                                30,000.00
--------------------------------------------------------------------------------------------------------------------------------------------------------
FISHER HOUSE FOUNDATION, INC.                                                                                                                 750,000.00
--------------------------------------------------------------------------------------------------------------------------------------------------------
FONDOS UNIDOS DE PUERTO RICO, INC.                                                                                                            136,400.00
--------------------------------------------------------------------------------------------------------------------------------------------------------
FOOD BANK OF EASTERN MICHIGAN                                                                                10,000.00
--------------------------------------------------------------------------------------------------------------------------------------------------------
GILDA'S CLUB CHICAGO                                                                                                          25,000.00        25,000.00
--------------------------------------------------------------------------------------------------------------------------------------------------------
GLOBAL HEALTH CORPS                                                        50,000.00       100,000.00       100,000.00       100,000.00       100,000.00
--------------------------------------------------------------------------------------------------------------------------------------------------------
GLOBEMED NFP                                                               50,000.00        75,000.00        75,000.00        75,000.00        75,000.00
--------------------------------------------------------------------------------------------------------------------------------------------------------
HABITAT FOR HUMANITY INTERNATIONAL                                                                                                            530,200.00
--------------------------------------------------------------------------------------------------------------------------------------------------------
HABITAT FOR HUMANITY, LAKE COUNTY IL, INC.                                                                                                    125,000.00
--------------------------------------------------------------------------------------------------------------------------------------------------------
HANDS ON ORLANDO, INC                                                                                                                         150,000.00
--------------------------------------------------------------------------------------------------------------------------------------------------------
HEALTHREACH, INC.
--------------------------------------------------------------------------------------------------------------------------------------------------------
HEART TO HEART INTERNATIONAL, INC.                                                                           35,000.00       535,000.00       310,000.00
--------------------------------------------------------------------------------------------------------------------------------------------------------
HISPANIC SCHOLARSHIP FUND                                                                                                                      50,000.00
--------------------------------------------------------------------------------------------------------------------------------------------------------
ILLINOIS SCIENCE AND TECHNOLOGY INSTITUTE                                                                    70,000.00        40,000.00        80,000.00
--------------------------------------------------------------------------------------------------------------------------------------------------------
IMPACTING VETERANS LIVES, INC.--MIDWEST VETERANS CLOSET                                                                                        50,000.00
--------------------------------------------------------------------------------------------------------------------------------------------------------
IMSA FUND FOR ADVANCEMENT OF EDUCATION                                    133,000.00       133,000.00        40,000.00
--------------------------------------------------------------------------------------------------------------------------------------------------------
INDIANA UNIVERSITY                                                      1,150,000.00     1,100,000.00     1,100,000.00     1,100,000.00     1,100,000.00
--------------------------------------------------------------------------------------------------------------------------------------------------------
INTERNATIONAL MEDICAL CORPS                                               100,000.00       350,000.00        25,000.00       450,000.00       550,000.00
--------------------------------------------------------------------------------------------------------------------------------------------------------
JK GROUP, INC. (Matching Grants)
--------------------------------------------------------------------------------------------------------------------------------------------------------
JUNIOR ACHIEVEMENT OF CHICAGO                                                                                33,500.00        50,000.00        50,000.00
--------------------------------------------------------------------------------------------------------------------------------------------------------
KABOOM!                                                                                                                      342,582.00       397,081.00
--------------------------------------------------------------------------------------------------------------------------------------------------------
KIDS RANK                                                                                                                                      25,000.00
--------------------------------------------------------------------------------------------------------------------------------------------------------
KOHL CHILDREN'S MUSEUM                                                                                      495,500.00
--------------------------------------------------------------------------------------------------------------------------------------------------------
KOHL CHILDREN'S MUSEUM OF GREATER CHICAGO                                  44,615.00                                         154,000.00       154,300.00
--------------------------------------------------------------------------------------------------------------------------------------------------------
LAKE COUNTY CARES                                                                           22,145.00        22,000.00
--------------------------------------------------------------------------------------------------------------------------------------------------------
LAKE COUNTY CRISIS CENTER FOR THE PREVENTION AND TREATMENT OF                               10,000.00        10,000.00        10,000.00        25,000.00
 DOMESTIC VIOLENCE, INC.
--------------------------------------------------------------------------------------------------------------------------------------------------------
LAKE COUNTY VETERANS AND FAMILY SERVICES FOUNDATION                                                                                            50,000.00
--------------------------------------------------------------------------------------------------------------------------------------------------------
MAP INTERNATIONAL                                                         313,800.00       412,907.00       460,000.00       510,000.00       325,000.00
--------------------------------------------------------------------------------------------------------------------------------------------------------
MASSACHUSETTS BIOTECHNOLOGY EDUCATION FOUNDATION                           40,000.00
--------------------------------------------------------------------------------------------------------------------------------------------------------
MEMORIAL SLOAN KETTERING CANCER CENTER                                    100,000.00       100,000.00       100,000.00       100,000.00       100,000.00
--------------------------------------------------------------------------------------------------------------------------------------------------------
MIDWEST ATHLETES AGAINST CHILDHOOD CANCER, INC                                                                  865.00
--------------------------------------------------------------------------------------------------------------------------------------------------------
MOTHERS TRUST FOUNDATION                                                                                                                       25,000.00
--------------------------------------------------------------------------------------------------------------------------------------------------------
NATIONAL AUDUBON SOCIETY, INC.                                            12 ,500.00
--------------------------------------------------------------------------------------------------------------------------------------------------------
NATIONAL INVENTORS HALL OF FAME, INC.                                     225,000.00       225,000.00       153,900.00       176,000.00       259,725.00
--------------------------------------------------------------------------------------------------------------------------------------------------------
NATIONAL MULTIPLE SCLEROSIS SOCIETY                                                                             350.00
--------------------------------------------------------------------------------------------------------------------------------------------------------
NICASA, NFP
--------------------------------------------------------------------------------------------------------------------------------------------------------
NORTH CHICAGO COMMUNITY PARTNERS                                          246,833.00       237,889,00       642,500.00       730,000.00       750,000.00
--------------------------------------------------------------------------------------------------------------------------------------------------------
NORTH CHICAGO COMMUNITY UNIT SCHOOL DISTRICT 187                                           100,600.00       165,000.00                        828,430.00
--------------------------------------------------------------------------------------------------------------------------------------------------------
NORTHERN ILLINOIS FOOD BANK                                                14,400.00        15,000.00        25,000.00        30,000.00        55,000.00
--------------------------------------------------------------------------------------------------------------------------------------------------------
PADS LAKE COUNTY, INC.                                                     10,000.00        10,000.00        10,000.00        10,000.00        25,000.00
--------------------------------------------------------------------------------------------------------------------------------------------------------
PARTNERS IN HEALTH                                                        100,000.00                        300,000.00       383,335.00       688,925.00
--------------------------------------------------------------------------------------------------------------------------------------------------------
POINTS OF LIGHT FOUNDATION                                                                                  545,800.00       708,000.00       954,000.00
--------------------------------------------------------------------------------------------------------------------------------------------------------
PRAIRIE STATE LEGAL SERVICES, INC.                                                          25,000.00        25,000.00        25,000.00        25,000.00
--------------------------------------------------------------------------------------------------------------------------------------------------------
PROJECT HOPE--THE PEOPLE-TO-PEOPLE HEALTH FOUNDATION, INC.                                                                   250,000.00       100,000.00
--------------------------------------------------------------------------------------------------------------------------------------------------------
READING POWER, INC.                                                        10,000.00        40,000.00        58,000.00       260,000.00       300,000.00
--------------------------------------------------------------------------------------------------------------------------------------------------------
ROSALIND FRANKLIN UNIVERSITY OF MEDICINE AND SCIENCE                       10,000.00        65,120.00
--------------------------------------------------------------------------------------------------------------------------------------------------------
SHEDD AQUARIUM                                                                                                                50,000.00        50,000.00
--------------------------------------------------------------------------------------------------------------------------------------------------------
SIEMPRE UNIDOS                                                             60,000.00
--------------------------------------------------------------------------------------------------------------------------------------------------------
SILICON VALLEY COMMUNITY FOUNDATION (Matching Grants)                   2,763,823.52     3,059,133.44       504,232.72
--------------------------------------------------------------------------------------------------------------------------------------------------------
STRENGTHEN ORLANDO, INC.                                                                                      6,515.00
--------------------------------------------------------------------------------------------------------------------------------------------------------
TAPROOT FOUNDATION                                                                                                                            200,000.00
--------------------------------------------------------------------------------------------------------------------------------------------------------
TEAM RUBICON                                                                                                                                  375,000.00
--------------------------------------------------------------------------------------------------------------------------------------------------------
TEXAS CHILDREN'S HOSPITAL                                                                                                     50,000.00
--------------------------------------------------------------------------------------------------------------------------------------------------------
THE ALS ASSOCIATION GREATER CHICAGO CHAPTER                                                                                                     5,000.00
--------------------------------------------------------------------------------------------------------------------------------------------------------
THE FULLER CENTER FOR HOUSING HERO PROJECT LAKE COUNTY                                                                                         60,000.00
--------------------------------------------------------------------------------------------------------------------------------------------------------
THE HEART OF AMERICA FOUNDATION                                           726,910.00     1,019,652.00     1,327,500.00     2,050,000.00     1,993,300.00
--------------------------------------------------------------------------------------------------------------------------------------------------------
THE SCRIPPS RESEARCH INSTITUTE                                                                                                                290,000.00
--------------------------------------------------------------------------------------------------------------------------------------------------------
TPA NETWORK INCORPORATED                                                                                      2,285.00
--------------------------------------------------------------------------------------------------------------------------------------------------------
TRAVIS MANION FOUNDATION                                                                                                                      100,000.00
--------------------------------------------------------------------------------------------------------------------------------------------------------
UNITED WAY OF CENTRAL MASSACHUSETTS                                                                          44,000.00        45,000.00        61,000.00
--------------------------------------------------------------------------------------------------------------------------------------------------------
UNITED WAY OF LAKE COUNTY                                                  80,000.00        80,000.00        70,000.00
--------------------------------------------------------------------------------------------------------------------------------------------------------
UNIVERSTIY OF CHICAGO                                                   1,000,000.00     1,000,000.00     1,000,000.00     1,000,000.00     1,000.000.00
--------------------------------------------------------------------------------------------------------------------------------------------------------
UNIVERSITY OF NOTRE DAME                                                                                                                       50,000.00
--------------------------------------------------------------------------------------------------------------------------------------------------------
WARRIORS AND QUIET WATERS FOUNDATION, INC.                                                                                                     50,000.00
--------------------------------------------------------------------------------------------------------------------------------------------------------
WILLIAM MARSH RICE UNIVERSITY                                              94,300.00
--------------------------------------------------------------------------------------------------------------------------------------------------------
WOUNDED WARRIOR PROJECT                                                                                                                       750,000.00
--------------------------------------------------------------------------------------------------------------------------------------------------------
WPS60                                                                                                       110,000.00
--------------------------------------------------------------------------------------------------------------------------------------------------------
YBLC, INC.                                                                 15,000.00        15,000.00        15,000.00
--------------------------------------------------------------------------------------------------------------------------------------------------------
YOUR CAUSE HOLDINGS, LLC (Matching Grants)                                                                2,805,067.87     4,120,115.28     7,012,295.67
--------------------------------------------------------------------------------------------------------------------------------------------------------
                                                                       12,292,102.52    13,593,332.35    15,187,786.59    19,856.907.28    26,850,256.67
--------------------------------------------------------------------------------------------------------------------------------------------------------
Note: Matching Grants are listed by Organizations that manage the program and not by the ultimate re

              Prepared Statement of Hon. Chuck Grassley, 
                        a U.S. Senator From Iowa
    I want to welcome the witnesses and thank them for being here.

    The information they share will help inform the committee as it 
addresses the issue of high prescription drug prices.

    America has a problem with the high cost of prescription medicines.

    Whether it's about the EpiPen, insulin, or other prescriptions, in 
the thousands of letters I've received, Iowans have made clear that 
high drug prices are hurting them.

    I've heard about people skipping doses of their prescription drugs 
to make them last until the next paycheck.

    I'm not a doctor, but rationing one's medicine doesn't sound like a 
safe prescription for health and wellness.

    Others have told me about leaving their prescription on the 
pharmacy counter because it cost too much.

    There is no question that researchers and doctors have developed 
treatments and cures for diseases where there were once none.

    And, such innovations take time and money.

    But, we're all trying to understand the sticker shock that many 
drugs generate. Especially when some of those drugs have been around 
for a long time.

    There is a balance between incentivizing innovation and keeping 
prices affordable for consumers and taxpayers.

    Like all systems, things can get out of balance.

    The good news is, we are here to discuss solutions.

    In fact, we are here today thanks to our system of checks and 
balances.

    Congress has a constitutional responsibility to be a meaningful 
check on the spending of taxpayer money.

    That responsibility includes not just holding hearings, but also 
holding the private sector and the government accountable through 
oversight.

    Just like a doctor has to properly diagnose a disease before it can 
be treated, Congress needs to understand what's going on in the drug 
pricing supply chain in order to respond in a measured and effective 
way.

    As a part of that fact-finding, as of last Friday, Ranking Member 
Wyden and I launched an inquiry into the high cost of insulin.

    This hearing is not about scapegoating any one group regarding high 
drug costs.

    That's why we're holding a series of bipartisan hearings on the 
issue.

    Without a doubt, drug pricing is a complex issue.

    But I think we should all be asking: Should it be so complex?

    We cannot allow anyone to hide behind the current complexities to 
shield the true cost of a drug.

    And, we shouldn't turn a blind eye to industry practices that 
thwart the laws and regulations designed to promote competition and 
generic drug entry in the market.

    Health and Human Services Secretary Alex Azar, FDA Commissioner 
Scott Gottlieb and the Federal Trade Commission have identified a 
number of tactics that undermine competition--like withholding samples, 
pay for delay, product-hopping, and rebate bundling, just to name a 
few.

    While these agencies are taking enforcement action or looking at 
regulatory changes, we here in Congress are exploring legislative 
options to deter companies from engaging in these practices that keep 
drug prices high for patients.

    Today, we expect open, honest answers from the pharmaceutical 
industry to figure out how we got here and see what ideas they have to 
make things better.

    One of the first things we need to talk about is list price.

    Secretary Azar has said that pharmaceutical companies believe that 
the list price is meaningless.

    In fact, some of your testimony today will echo that.

    However, for a patient taking a drug that has no competition, the 
list price is meaningful.

    For seniors on Part D who are paying co-insurance as a percentage 
of list price, the list price is meaningful.

    For people who have high deductible plans and pay thousands of 
dollars towards list price, the list price is meaningful.

    For pharmacy benefit managers, providing drugs with a high list 
price can be more attractive than providing a less expensive drug.

    Therefore, for taxpayers, the list price is meaningful.

    We've all seen the finger pointing. Every link in the supply chain 
has gotten skilled at that.

    But, like most Americans, I'm sick and tired of the blame game.

    It's time for solutions.

    One way or another, we're going to get some clarity.

    The American people deserve straight answers and real solutions.

    On that note, I want to remind each of you that it's a crime under 
title 18, U.S. Code, section 1001 to provide false testimony to 
Congress.

    Thank you for coming. I look forward to your testimony.

                                 ______
                                 
                 Prepared Statement of Pascal Soriot, 
                  Chief Executive Officer, AstraZeneca
                              i. overview
    AstraZeneca appreciates the opportunity to engage with the 
committee on the important topic of drug pricing in the United States. 
We would like to emphasize our commitment to addressing these 
challenges and the important issues raised by the committee regarding 
drug pricing and affordability.

    AstraZeneca is a global, science-led biopharmaceutical company that 
focuses on the discovery, development and commercialization of 
prescription medicines, primarily for the treatment of diseases in 
three main therapy areas: Oncology; Cardiovascular; Renal and 
Metabolism; and Respiratory. We are also selectively active in the 
areas of autoimmunity, neuroscience, and infection. We are proud to 
call Wilmington, DE home to our North American headquarters. We are 
equally proud that one of our three global Research and Development 
(``R&D'') headquarters is located in Gaithersburg, MD.

    We are honored to contribute to improving the lives of millions of 
patients in the U.S. and across the globe. This statement is focused on 
four points explaining AstraZeneca's purpose, core values, and vision 
for the future:

          First, we are a science-led organization, as reflected in 
        our continued investment in R&D and our success in introducing 
        new treatments. Continuing to develop treatments that deliver 
        long-term benefits to patients and the overall health of the 
        U.S. population requires society's commitment to supporting 
        investment in innovation through purchasing our medicines for 
        the duration of patent protection at a responsible price that 
        allows for the recoupment of the investment and risk associated 
        with innovation.

          Second, we believe medicines are part of the solution to 
        controlling health-care costs. They not only improve patient 
        outcomes and increase quality of life, but also reduce 
        downstream costs by keeping people healthy and out of the 
        hospital. This contribution to reducing overall health-care 
        costs should be considered when discussing drug pricing.

          Third, we recognize that we are only able to improve the 
        lives of patients if they are able to take our medicines as 
        prescribed. To that end, we are committed to sustaining and 
        improving patient access and affordability.

          Fourth, we recognize that the current state of drug pricing 
        in the U.S. health-care system is not sustainable and that 
        patients are facing increasingly high out-of-pocket costs. We 
        believe that these issues must be addressed urgently, and we 
        hope to be a constructive partner in finding solutions.
               ii. benefits of innovation and r&d funding
    Science is at the core of what we do, and we are focused on being 
at the forefront of scientific innovation to deliver tomorrow's 
treatments and cures. Since 2017, the Food and Drug Administration 
(``FDA'') has approved 18 AstraZeneca products or significant 
indications, and five of our products have received breakthrough 
therapy designation. Breakthrough therapy designation is designed 
specifically for the expedited development and review of drugs for 
serious or life-threatening conditions, and these designations 
highlight how critical our work is to patient health in the U.S. For 
example, our oncology medicine CALQUENCE was granted breakthrough 
therapy designation for certain patients with mantle cell lymphoma and 
tezepelumab received such a designation for certain patients with 
severe asthma.

    In order to achieve these results, we reinvest a significant 
percentage of our revenues in research to identify the next generation 
of life-changing medicines. Over the past several years, we have worked 
tirelessly to rebuild our R&D pipeline. We now have approximately 8,900 
employees in our R&D organization working at sites across the world. 
Our financial commitment to R&D has been significant. In 2018 alone, we 
spent nearly $6 billion on R&D, or 28 percent of our total product 
sales--a commitment to R&D that well exceeds the average spending of 
our research-based peers.\1\ Over the past six years, even as our 
revenues declined, we continued to make substantial investments in both 
R&D and acquiring products for our pipeline. In 2018, these investments 
have only just started to contribute to growth of our company.
---------------------------------------------------------------------------
    \1\ Pharmaceutical Research and Manufacturers of America (PhRMA). 
PhRMA Annual Membership Survey (2018). https://www.phrma.org/report/
2018-phrma-annual-membership-survey.

    These results are possible only if society makes a commitment to 
support innovation so that treatments can be developed to the benefit 
---------------------------------------------------------------------------
of society as a whole for years to come.

    The development of new drug therapies requires society to make an 
up-front investment through purchasing our medicines during the patent 
protection period at a responsible price we charge, and then at a very 
substantially reduced price for an indefinite period after patent 
expiry when generics are introduced. Thus, long-term improvements in 
healthcare derived from new medicines can only be achieved if society 
is willing to pay a responsible price for a certain number of years 
that allows for the recoupment of the investment and risk involved in 
pharmaceutical innovation. Improvements in patient health and reduction 
of overall health-care costs over the long term are a direct result of 
this commitment to support innovation.

    For example, in the U.S., we have seen incredible progress in 
reducing cardiovascular disease morbidity and mortality. Between 2000 
and 2014, age-adjusted mortality rates for cardiovascular and heart 
disease declined by approximately 35 percent; several factors have 
contributed to this decline, but the development of new medicines, 
including cholesterol-lowering medicines like statins, has played an 
important role.\2\ To take an AstraZeneca example, CRESTOR, a statin, 
was approved by the FDA in 2003. A study of CRESTOR showed that it 
reduced cardiovascular mortality and morbidity over the lifetime of the 
patient compared to the standard of care, resulting in economic 
value.\3\
---------------------------------------------------------------------------
    \2\ Sidney S, Quesenberry CP, Jr, Jaffe MG, Sorel M, et al. Recent 
trends in cardiovascular mortality in the United States and public 
health goals. JAMA Cardiol. 2016;1(5):594-599. doi: 10.1001/
jamacardio.2016.1326.
    \3\ Ohsfeldt RL, Gandhi SK, Smolen LJ, et al. Cost effectiveness of 
rosuvastatin in patients at risk of cardiovascular disease based on 
findings from the JUPITER trial. J Med Econ. 2010;13(3):428-37. doi: 
10.3111/13696998.2010.499758.

    It is important to note that there are significant risks involved 
in developing new therapies. Only approximately 12 percent of therapies 
entering clinical study are approved, and the average cost of 
development approaches $2.6 billion.\4\ In 2018, return on R&D 
investment among larger biopharmaceutical manufacturers fell to 1.9 
percent, its lowest point since 2010.\5\ If we are not successful, we 
lose our investment in the therapy. Although we are proud of our 
success rate, we know that setbacks are inevitable when pushing the 
boundaries of science. For example, in 2018, we announced with our 
partner Lilly the discontinuation of Phase III clinical trials of 
lanabecestat, an investigational treatment for Alzheimer's disease. 
Such results are disappointing, but are an integral part of the nature 
of scientific discovery.
---------------------------------------------------------------------------
    \4\ DiMasi JA, Grabowski HG, Hansen RA. Innovation in the 
pharmaceutical industry: new estimates of R&D costs. J Health Econ. 
2016;47:20-33. doi: 10.1016/j.jhealeco.2016.01.012.
    \5\ Deloitte Centre for Health Solutions. Unlocking R&D 
Productivity: Measuring the return from pharmaceutical innovation 2018. 
https://www2.deloitte.com/us/en/pages/life-sciences-and-health-care/
articles/measuring-return-from-pharmaceutical-innovation.html.

    Given the risks involved in developing a medicine, strong 
intellectual property (``IP'') protections and exclusivity for 
innovator products are a key component to ensuring that manufacturers 
continue to develop therapies that benefit society as a whole. While 
they create incentives to innovate, it is important to note that IP 
protections and exclusivity for innovator therapies do not generally 
prevent other competitor therapies from entering a given class, 
allowing robust competition to exist; for example, there are seven 
---------------------------------------------------------------------------
different statin molecules approved in the marketplace.

    Once these protections expire, generic and biosimilar competitors 
can enter the market, which further increases competition. Again, 
taking CRESTOR as example, since 2016 when it lost exclusivity, over 16 
generic forms have been approved and are available in the market today, 
driving prices down very substantially. We strongly support this 
construct and policy efforts to encourage competition. We describe 
these proposals in section V of this statement.

    Finally, it is also worth noting that a significant portion of our 
R&D occurs here in the U.S. We invest more than $2.7 billion annually 
in U.S.-based R&D work, employing approximately 2,700 people in our 
science units within our R&D centers in Maryland, Massachusetts, and 
California. Our approach to R&D is consistent with our broader and 
long-standing commitment to U.S. jobs in research and manufacturing. 
Our largest footprint is in this country, with 12,800 employees 
throughout the U.S. Additionally, we recently completed a $200 million 
expansion in our Frederick, MD facility where biologics, including 
FASENRA for certain patients with severe asthma, and our immuno-
oncology therapy, IMFINZI, are manufactured. This sustained investment 
in R&D leads to the creation of high-quality jobs and generates 
economic value in the U.S.

    To summarize, because we have put science and research at the 
center of our company, we have had more success in our R&D pipeline 
than ever before, delivering long-term healthcare benefits. This 
success, however, is only possible if society remains committed to 
supporting investment in innovation.
                        iii. value of medicines
    The investments we make in researching and developing new therapies 
cannot occur in a vacuum. We must also ensure that our medicines bring 
value to patients, payers, and the health-care system as a whole.

    We are only able to stand behind the value of our medicines if that 
value is carefully and appropriately defined. In the health-care 
industry and as part of policymaking, there is frequent reflection on 
the meaning of ``value.'' We believe value must be assessed 
holistically and include all costs related to the treatment of a given 
condition. In particular, we must consider improvements in clinical 
outcomes and quality of life as well as reduction of hospitalizations 
and other medical costs.

    Additionally, the future savings that prescription medicines can 
bring to the healthcare system by preventing more costly interventions 
should not be overlooked as their value is considered. A recent study 
in Health Affairs of total Medicare spending per beneficiary from 1999 
to 2012 found that the spending growth rate slowed to just 1.1 percent 
per year on average since 2005. The study found that half of the total 
slowdown was attributable to reduced spending growth on cardiovascular 
diseases and events, like heart attacks and related conditions. 
Increased medication use for conditions like hypertension, high 
cholesterol, and diabetes explained half of that effect. The authors 
noted that while large, even this impact of medications is likely to be 
understated.\6\
---------------------------------------------------------------------------
    \6\ Cutler D, Ghosh K, et al., Explaining the Slowdown in Medical 
Spending Growth Among the Elderly, 1999-2012. Health Affairs. February 
2019. doi: 10.1377/hlthaff.2018.05372.

    One of our own therapies--BRILINTA--is an example of a medicine 
used in the cardiovascular setting that brings value to both patients 
and the broader health-care system. This oral antiplatelet therapy is 
indicated to reduce the rate of cardiovascular death, heart attack, and 
stroke in patients with acute coronary syndrome (``ACS'') or a history 
of heart attacks. For at least the first 12 months following the 
diagnosis of ACS, BRILINTA has been shown to be superior to 
clopidogrel, a generic oral antiplatelet. In addition, in patients with 
ACS, BRILINTA in combination with aspirin resulted in 21 percent 
reduction in cardiovascular mortality compared to clopidogrel in 
combination with aspirin.\7\
---------------------------------------------------------------------------
    \7\ Wallentin L, Becker RC, Budaj A, et al. Ticagrelor versus 
clopidogrel in patients with acute coronary syndromes. N Engl J Med. 
2009;361(11):1045-57. doi: 10.1056/NEJMoa0904327.

    In addition, BRILINTA in combination with aspirin also resulted in 
lower medical care costs compared to clopidogrel in combination with 
aspirin. The lower medical costs are driven primarily by fewer hospital 
readmissions and cardiovascular revascularization interventions--
resulting in medical care cost offsets of approximately $1,000 per 
patient per year.\8\ This represents countless hours of patient time 
better spent with family and friends than in the hospital.
---------------------------------------------------------------------------
    \8\ Data on file. 2134602; AstraZeneca Pharmaceuticals LP.

    Another example of the value that medicines can provide relates to 
the relationship between diabetes and heart failure. In 2015, an 
estimated 30.2 million adults in the U.S. had diabetes, with the vast 
majority (90-95 percent) having type 2 diabetes.\9\ Up to 50 percent of 
patients with type 2 diabetes may develop heart failure.\10\ The 
prevalence of heart failure in the U.S. is expected to increase from 
5.8 million in 2012 to 8.5 million in 2030.\11\ The total cost of heart 
failure, which includes direct and indirect costs, is projected to 
increase from $31 billion in 2012 to $70 billion in 2030, with the 
majority of these costs (80 percent) related to hospitalization.\12\
---------------------------------------------------------------------------
    \9\ Centers for Disease Control and Prevention (CDC). National 
Diabetes Statistics Report, 2017. https://www.cdc.gov/diabetes/pdfs/
data/statistics/national-diabetes-statistics-report.pdf.
    \10\ American Diabetes Association. CV Disease and risk management: 
standards of medical care in diabetes--2019. Diabetes Care. 
2019;42(Suppl 1);S103-S123. doi: 10.2337/dc19-S010.
    \11\ Heidenreich P, Albert N, Allen L, et al. Forecasting the 
impact of heart failure in the United States: a policy statement from 
the American Heart Association. Circ Heart Fail. 2013;6:606-619. doi: 
10.1161/HHF.0b013e318291329a.
    \12\ Id.

    Our oral type 2 diabetes product FARXIGA is a sodium-glucose 
cotransporter 2 (SGLT2) inhibitor. This newest class of oral diabetes 
medication has consistently demonstrated cardiovascular benefits for 
diabetes patients that are absent in older diabetes treatments, further 
supporting the importance of biopharmaceutical innovation. A recent 
cardiovascular outcomes trial demonstrated that FARXIGA significantly 
reduced the risk for hospitalization for heart failure or 
cardiovascular death.\13\ With initial hospitalizations and 
readmissions for heart failure in the Medicare population exceeding 
$10,000 for each event in the U.S., it can be readily observed where 
these new therapies can help further reduce total cost of care in the 
most at-risk patient populations.\14\
---------------------------------------------------------------------------
    \13\ Wiviott SD, Raz I, Bonaca MP, et al. for the DECLARE-TIMI 58 
Investigators. Dapagliflozin and cardiovascular outcomes in type 2 
diabetes [published online ahead of print November 10, 2018]. N Engl J 
Med. 2018. http://dx.doi.org/10.1056/NEJMoa1812389. Accessed November 
10, 2018.
    \14\ Ziaeian B, Heidenreich PA, Xu H, et al. Medicare expenditures 
by race/ethnicity after hospitalization for heart failure with 
preserved ejection fraction. JACC Heart Fail. 2018;6:388-97. doi: 
10.1016/j.jchf.2017.12.007.

    In highly complex conditions, the measure of value and 
effectiveness can be more multifaceted. In cancer, for example, there 
are several end-points to measure effectiveness, such as progression-
free survival and overall survival. To account for this complexity, 
cost-effectiveness studies for cancer therapies can measure the value 
in providing the medication earlier in the course of treatment. An 
example from our portfolio is IMFINZI--currently the only FDA-approved 
immunotherapy for the treatment of patients with unresectable stage III 
non-small cell lung cancer whose cancer has not progressed following 
platinum-based concurrent chemoradiation therapy. Before IMFINZI, 
patients in this setting underwent a period of ``watch and wait'' after 
chemoradiation,\15\ and for up to 89 percent of these patients their 
cancer was likely to spread further.\16\ Based on the PACIFIC trial, 
IMFINZI may reduce the risk of death for these patients by nearly a 
third.\17\
---------------------------------------------------------------------------
    \15\ Postmus PE, Kerr KM, Oudkerk M, et al. Early and locally 
advanced non-small-cell lung cancer (NSCLC): ESMO Clinical Practice 
Guidelines for diagnosis, treatment and follow-up. Annals of Oncol. 
Published online July 1, 2017. doi: 10.1093/annonc/mdx222.
    \16\ Albain KS, Swann RS, Rusch VW, et al. Radiotherapy Plus 
Chemotherapy With or Without Surgical Resection for Stage III Non-Small 
Cell Lung Cancer. Lancet. Published online August 1, 2009. doi: 0.1016/
S0140-6736(09)60737-6.
    \17\ Antonia SJ, Villegas A, Daniel D, et al. Overall survival with 
durvalumab after chemoradiotherapy in stage III NSCLC. N Engl J Med. 
2018;379(24):2342-2350. doi: 10.1056/NEJMoa1809697. Epub 2018 Sep 25.

    In a recent analysis, use of IMFINZI was found to be cost-effective 
in comparison to the previous ``watch and wait'' approach to treatment. 
This cost-effectiveness analysis, published in the Journal of the 
American Medical Association in December 2018, indicates that although 
IMFINZI consolidation therapy increased national cancer spending, 
treating earlier in the course of cancer progression may provide 
significant value.\18\
---------------------------------------------------------------------------
    \18\ Criss SD, Mooradian MJ, Sheehan DF, et al. Cost-effectiveness 
and Budgetary Consequence Analysis of Durvalumab Consolidation Therapy 
vs. No Consolidation Therapy After Chemoradiotherapy in Stage III Non-
Small Cell Lung Cancer in the Context of the U.S. Health Care System. 
JAMA Oncol. Published online December 13, 2018. doi: 10.1001/
jamaoncol.2018.5449.

    For a drug therapy to bring the most value to patients and the 
health-care system, it is imperative that the therapy is reaching the 
right patients at the right point in their treatment journeys. At 
AstraZeneca, we are focused on improving outcomes for patients on a 
personalized level by identifying the most appropriate treatments. 
Approximately 90 percent of our pipeline now has a precision medicine 
approach and reflects the broad range of cutting-edge technologies, 
tissue diagnostics, next-generation sequencing and point of care 
diagnostics we have introduced. By more precisely matching patients 
with the right medicine, we bring greater value to payers and the 
health-care system and help to ensure that patients receive the 
---------------------------------------------------------------------------
specific therapy that is most appropriate for their treatment needs.

    Finally, the concept of value is a key component in our pricing 
determinations. AstraZeneca has always taken a thoughtful approach to 
pricing, and we continue to do so, considering many factors. In 
addition to our significant R&D investments, we consider clinical 
value, size of patient population, government/payer coverage 
requirements, patient affordability, competition and other market 
conditions. We remain committed to pricing responsibly and making our 
medicines available and affordable to patients.
           iv. commitment to patient access and affordability
    Although we are thoughtful in our approach to pricing, we know that 
patients continue to face challenges at the pharmacy counter. We fully 
recognize that drug therapies cannot bring value to the health-care 
system or to patients unless they can access the medicines they need.

    Our commitment to affordable access translates into a number of 
resources and programs that have helped make our medicines available to 
patients.
A. AstraZeneca Savings and Affordability Programs
    To ensure that patients in the U.S. are aware of our affordability 
programs, we were the first company to include messages about these 
programs in all of our U.S. television advertisements. Since 2005, 
every televised advertisement has reminded viewers: ``If you can't 
afford your medication, AstraZeneca may be able to help.''

    We stand behind this statement. Forty years ago, we were one of the 
first manufacturers in our industry to establish a patient assistance 
program to help low-
income patients obtain certain medicines free of charge. Through our 
``AZ&Me'' program, we have provided prescription drug savings to more 
than four million patients in the U.S. and Puerto Rico between 2008 and 
2018.

    In addition to AZ&Me, we offer extensive copay savings programs to 
help eligible, commercially insured patients reduce copay costs at the 
pharmacy. These copay savings programs are unfortunately not available 
to Part D patients and this has created challenges for this population, 
reducing adherence to important lifesaving or life-improving 
treatments.
B. Value-Based Agreements
    We are also working closely with payers and health systems to 
explore innovative solutions to improve access and affordability that 
demonstrate the value our medicines bring to patients and the health-
care system. For several years, AstraZeneca has been exploring these 
types of solutions through value-based agreements where we are willing 
to work with health-care stakeholders to tie payment to patient 
outcomes.

    To date, we have entered into approximately 40 value-based 
agreements across our therapeutic areas with a variety of payers, 
making AstraZeneca a leader in the field of value-based agreements. As 
an example, AstraZeneca agreed with Express Scripts that for IRESSA, an 
oral treatment for certain types of lung cancer, we will fully 
reimburse Express Scripts for discontinued use before the third fill, 
including if discontinuation occurs because patients did not respond to 
treatment.

    While most of these agreements have been focused on securing 
patient access to our medicines and delivering better patient outcomes, 
where payers are willing, we are also looking to more directly address 
patient out-of-pocket affordability through these innovative 
arrangements.

    As an example, last month, we announced the initiation of a value-
based agreement for University of Pittsburgh Medical Center (``UPMC'') 
Medicare patients who are prescribed BRILINTA. This value-based 
contract, which was effective as of January 1, 2019, is groundbreaking 
in two ways. First, the contract lowers the out-of-pocket costs for a 
UPMC Medicare Part D patient to approximately $10 for a 30-day supply. 
Second, what UPMC pays for BRILINTA will vary based on patient 
outcomes, tying the cost of the drug to its real-world clinical 
performance.

    We are currently exploring another value-based agreement in 
Medicare Part D. In addition to having a significant outcomes-based 
component, this arrangement would reduce patient out-of-pocket costs. 
This type of agreement allows patients to access their medicines at a 
lower out-of-pocket cost and payers to control their overall health-
care costs through paying for outcomes.

    However, there remain significant operational and regulatory 
hurdles to the broader implementation of value-based agreements. 
Operational challenges include capturing appropriate data and other 
capabilities on the part of payers that are needed to successfully 
execute these arrangements. For example, value-based agreements 
typically require plans to have systems in place to report measures 
like adherence and readmissions. While many payers and health systems 
are evolving to meet the needs of the changing health-care environment, 
greater investments need to be made in data capabilities. In addition, 
policy and regulations must advance to support value-based agreements 
in becoming a standard approach to reimbursement.

    We believe that there are steps the government can take to address 
these challenges to help encourage the timely adoption of value-based 
agreements, including in public sector programs like Medicare. These 
recommendations are described in more detail in section V of this 
statement. Through the partnership of payers and policymakers, we look 
forward to a future where implementation of value-based agreements 
across public and private payers is widespread.
C. Discounts and Rebates
    Finally, we negotiate rebates and discounts with payers and 
pharmacy benefit managers (``PBMs'')--including in Medicare Part D--to 
help ensure that our therapies have the most robust access possible. 
Without providing these discounts and rebates, many life-savings 
medicines would not be placed on plan formularies and therefore would 
be largely unavailable to the patients who need them most. Our 
estimates for 2018 show that across our products, our average rebate is 
nearly 50 percent of our gross revenues in the U.S. Taking BRILINTA as 
an example, approximately one third of gross revenue is provided back 
in rebates. For most of our diabetes therapies, rebates well exceed 50 
percent of gross revenues.

    Over the past several years, discounts and rebates for our 
therapies have increased overall, both in the commercial sector and 
Part D. In recent years, in our primary care portfolio, which includes 
the majority of our therapies, we have seen flat to declining net 
effective prices to AstraZeneca for most of our products. Taking 
CRESTOR as an example, in the 5-year period before it lost exclusivity, 
even though list price increased, in 2011, CRESTOR's average net 
effective price earned by AstraZeneca was $2.52 per day (one pill per 
day). In 2016 when CRESTOR lost exclusivity, the average net effective 
price was again $2.52.

    However, discounts and rebates do not necessarily translate to 
lower cost-sharing for patients. There are a series of factors that 
impact a patient's out-of-pocket costs, including individual insurance 
plan benefit design (copayments, coinsurance, and deductibles), 
formulary placement, provider access, and assistance programs or 
savings offers. As a science-led, patient-focused company, the fact 
that many patients struggle with out-of-pocket costs despite the 
discount and rebates we provide stands counter to our mission of 
improving patient health.
            v. the path forward: evolving the current system
    Despite rapidly increasing rebate amounts, affordability of drug 
therapies is an increasingly significant public policy and public 
health issue. We agree that the current system is not sustainable--for 
patients, payers, and society as a whole--and we are committed to 
engaging across stakeholders to develop a new paradigm that improves 
affordability and access for patients while ensuring that manufacturers 
can continue to develop innovative therapies.

    To achieve these goals of improving affordability and supporting 
innovation, we must progress from a volume-based to a value-based 
health-care system. We continue to be forward-leaning in this regard, 
and we encourage other stakeholders to join us in the effort to deliver 
and pay for health care, including drug therapies, in a more 
affordable, efficient, and effective way.

    An important step is to evolve the current system of paying for and 
delivering drug therapies to one in which patients more directly 
benefit from the discounts and rebates we provide. Specifically, we 
believe that patient cost-sharing should be more aligned to a product's 
net price as opposed to its list price, as is the case today.

    However, as we look ahead to the future, even more must be done to 
improve patient affordability and to truly build a health-care system 
based on the value of therapies provided to patients.
A. Value-Based Agreements Should Be the Future Standard
    First, in a future system, the default approach should be that 
pricing and reimbursement for drug therapies are tied to patient 
outcomes and the value the particular therapy provides. As such, it is 
imperative that manufacturers and payers--including Part D plans--
engage in value-based agreements similar to the IRESSA and BRILINTA 
examples referenced previously. Policies to encourage these 
arrangements and to reduce or eliminate existing challenges will be 
essential to their long-term success. To that end, AstraZeneca 
appreciates the support of Senators Warner and Cassidy for value-based 
agreements, as demonstrated by their requests for input on the Patient 
Affordability Value and Efficiency (``PAVE'') Act. This draft 
legislation would promote the development of value-based agreements by 
offering increased flexibility for manufacturers to enter into such 
arrangements, including with Medicare Part D plans.

    In addition to the policies outlined in the PAVE Act, there are 
other ways that the government could facilitate value-based agreements. 
For example, the Department of Health and Human Services (``HHS'') 
should consider how its recent proposed rule regarding PBM rebates can 
be structured to protect existing and future value-based agreements. We 
appreciate that HHS solicited comments on this topic, and we look 
forward to sharing our perspective in our written comments to the 
proposal. In addition, to encourage utilization of agreements that best 
address the government's goals, we recommend that HHS develop a 
prioritized list of clinical outcomes measures for manufacturers and 
payers to consider when developing outcomes-based agreements.

    Over the past several years, we have engaged with HHS, and 
specifically the Center for Medicare and Medicaid Innovation 
(``CMMI''), to advance specific models involving our therapies in the 
Medicare program. To date, we have not been able to execute on a model 
with HHS or CMMI and the feedback we have received is that company-
specific models are challenging to implement. We look forward to 
continued dialogue on these issues, and we hope to work with HHS, CMMI 
and other stakeholders to develop a scalable framework in which 
innovative models can be implemented in an appropriate way.
B. All Patients, Including Medicare Patients, Should Benefit From 
        Reduced Cost-Sharing
    Second, a future system should be designed to ensure that all 
patients benefit from lower cost-sharing, including those patients 
taking drug therapies on the Part D specialty tier. A recent study 
found that rates of prescription abandonment and delayed initiation of 
oral cancer therapies increase as cost-sharing amounts rise.\19\ Such a 
result reflects the need for a restructuring of the current benefit 
design for specialty products.
---------------------------------------------------------------------------
    \19\ Doshi JA, Li P, Petit AR, et al. Association of Patient Out-
of-Pocket Costs With Prescription Abandonment and Delay in Fills of 
Novel Oral Anticancer Agents. J Clin Oncol. 2018; 36(5): 476-482. doi: 
10.1200/JCO.2017.74.5091.

    Under one potential approach, a portion of manufacturer discounts 
could be used to fund a reduction in cost-sharing for patients facing 
the highest cost-sharing amounts. This could be accomplished by 
establishing a monthly or annual out-of-pocket cap, which would give 
patients greater certainty in the total amount of out-of-pocket costs 
they could face. The cap would provide a safety-net for patients that 
could be funded by a portion of the discounts provided across all Part 
D products. Such an approach would help ensure that more patients 
benefit from the discounts manufacturers provide.
C. Use of Biosimilars Should Be Supported
    Third, we believe that competition is a key component to reducing 
costs, and that is why we support expanded use of biosimilars in the 
U.S. As a global company, we operate in countries, particularly those 
in the European Union, where biosimilar competition is particularly 
robust. We support a similarly vigorous biosimilars market in the U.S.

    We therefore appreciate the efforts of the FDA to increase the 
availability of biosimilars in the U.S., including the FDA's 
development of a Biosimilars Action Plan. We support efforts to 
streamline and improve the efficiency of the biosimilars approval 
pathway for the benefit of patients.

    We also support reimbursement policies that facilitate the uptake 
of biosimilars. Such policies include Medicare reimbursement rates that 
ensure that biosimilars can compete on equal footing with innovator 
products.
            d. market-based competition should be maintained
    Finally, it is imperative to maintain market-based competition 
between manufacturers and between plans. Market-based competition plays 
an important role in keeping costs down. This is how the lifecycle of 
innovator therapies works today when competitors enter the market and 
generic medicines become available over time.

    The competitive market in the U.S. also provides patients with 
access to innovative medicines faster. For example, American patients 
have access to cancer medicines about 2 years earlier than patients in 
other countries, including Germany, France, and the U.K.\20\ This 
timely access to new cancer therapies is correlated with improved 
survival rates; from 1997 to 2012, rates of cancer mortality fell by 20 
percent in the U.S., compared to a 15 percent reduction in the U.K.\21\ 
Additionally, nearly 90 percent of newly launched medicines from 2011 
to 2017 were available in the U.S., compared to just two-thirds in the 
U.K., half in Canada and France, and one-third in Australia; and of 14 
new diabetes medicines launched over that period, only one was 
available in France.\22\ Given the benefits brought to patients by new 
antidiabetic agents such as SGLT2 inhibitors (reduction in heart 
failure and hospitalizations for heart failure), U.S. patients and 
payers greatly benefit from the earlier introduction of these 
innovative medicines.
---------------------------------------------------------------------------
    \20\ PhRMA analysis of IMS Consulting Group ``Patient Access to 
Innovative Oncology Medicines Across Developed Markets.'' June 2016.
    \21\ World Health Organization (WHO). WHO mortality database. 
http://www.who.int/healthinfo/mortality_data/en. PhRMA analysis of WHO 
mortality database, using age--specific death rates.
    \22\ PhRMA analysis of IQVIA Analytics.

    While the current system needs reform, some of the benefits to the 
current structure are the speed of access and reimbursement of new 
medicines and the robust nature of the negotiations between 
manufacturers and PBMs, which in turn creates competition between 
manufacturers. As the system evolves, it is important that this ability 
to compete is maintained. Therefore, there must be flexibility to 
continue to negotiate net price by product and indication, among other 
---------------------------------------------------------------------------
factors.

    This flexibility is necessary not only to maintain competition, but 
also to facilitate additional innovations in the way drugs are priced 
and reimbursed. For example, variable discounts could be used to reduce 
cost-sharing for patients over time as they remain adherent to their 
medications. Additionally, we support the concept of indication-based 
pricing, which recognizes that the value of a drug therapy with more 
than one indication may vary based on indication. Indication-based 
pricing would allow greater competition among manufacturers based on 
the clinical efficacy of their therapies on an indication-by-indication 
basis. Allowing discounts to vary based on the indication for which a 
therapy is prescribed will be key to facilitating indication-based 
pricing.

    Finally, we would like to acknowledge that the coverage and 
reimbursement policies in Medicare Part B have been criticized for not 
sufficiently encouraging price competition for physician-administered 
drug therapies. We are supportive of reforms in the Medicare Part B 
program to address these concerns. Such reforms could include an 
inflation penalty if a manufacturer's price increase exceeds a certain 
threshold, as well as steps to ensure that the government and Medicare 
patients more directly benefit from the discounts and rebates provided 
in the commercial sector. Similar to the suggestion above on creating a 
Part D out-of-pocket cap funded by a portion of manufacturer discounts, 
the savings generated from an inflation penalty and increased 
competition in Part B could be used to fund an out-of-pocket cap for 
Medicare Part B patients.

    Competition is a fundamental requirement to reducing costs over 
time, both in Medicare Part B and Part D. Flexibility in the future 
system will be necessary to maintain competition and to explore 
additional innovations in the pricing and reimbursement of drug 
therapies. We must also be willing to work together to improve the 
efficiency of the Part B program. We look forward to working with 
policymakers and other stakeholders to shape the future system to 
accomplish these goals.
                             vi. conclusion
    Although there is no single solution to the challenges we face, we 
welcome the opportunity to speak with you about ways to evolve our 
health-care system. We share your concern that many patients are facing 
challenges with out-of-pocket costs, and we are committed to working 
towards solutions that support patient access and affordability while 
sustaining innovation. AstraZeneca, along with many others in the 
pharmaceutical industry, is innovating to discover and develop 
tomorrow's cures and treatments, and we know we need to be a 
constructive partner to find solutions to ensure that patients benefit 
from the therapies we develop.

                                 ______
                                 
          Questions Submitted for the Record to Pascal Soriot
               Questions Submitted by Hon. Chuck Grassley
    Question. At the hearing, you testified that AstraZeneca does not 
withhold samples from generic manufacturers in order to block generic 
versions of your drug from entering the market. You also expressed your 
support for the ``Creating and Restoring Equal Access to Equivalent 
Samples Act,'' also known as the CREATES Act. However, the FDA has a 
list on its website which identifies reference listed drug (RLD) access 
inquiries where brand manufacturers may have prevented generic 
companies from obtaining samples of products necessary to support FDA 
approval. AstraZeneca is on this FDA list. This would appear to 
contradict your testimony at the hearing that AstraZeneca has not 
withheld samples of their products to delay generic competition.

    Could you please explain in detail why AstraZeneca is on the FDA 
list?

    Answer. AstraZeneca appreciates the opportunity to address the 
question of one of our medicines, BRILINTA (ticagrelor) appearing on 
the Reference Listed Drug Access Inquiries list (RLD List). We would 
first like to state that AstraZeneca supports allowing generic 
manufacturers access to samples. Withholding or otherwise blocking such 
access is inconsistent with that position. Our internal review has not 
identified any unanswered, delayed, or outstanding requests for samples 
of BRILINTA by any generic manufacturers.

    It is our understanding that BRILINTA was included on the RLD List 
based on a single inquiry received by the FDA. Unfortunately, the RLD 
List does not identify the company that reportedly requested 
information (or samples) from AstraZeneca, the date the information was 
requested, or any other information that would allow AstraZeneca to 
better understand or further investigate the circumstances of this 
inquiry. On its website, the FDA does advise that it has ``not 
independently investigated or confirmed the access limitations 
described in the inquiries received.'' \1\ Given this limitation, the 
listing of an inquiry on the RLD List does not mean that the FDA has in 
fact determined that access to samples by generic manufacturers was 
limited or withheld for the medicines identified. Indeed, based on our 
internal review, we have not identified any circumstances that 
substantiate the inquiry received by the FDA relating to BRILINTA.
---------------------------------------------------------------------------
    \1\ Reference Listed Drug (RLD) Access Inquiries, U.S. Food and 
Drug Administration, https://www.fda.gov/Drugs/
DevelopmentApprovalProcess/HowDrugsareDevelopedandApproved/
ApprovalApplications/AbbreviatedNewDrugApplicationANDAGenerics/
ucm607738.htm (last updated Feb. 7, 2019).

    Question. Could you please explain in detail the discrepancy 
---------------------------------------------------------------------------
between your testimony and the FDA list?

    Answer. AstraZeneca is not aware of any instances where the company 
has withheld or otherwise blocked access to samples by generic 
manufacturers. Based on our internal review, AstraZeneca is not aware 
of any unanswered, delayed, or outstanding requests for samples of 
BRILINTA by any generic manufacturers.

    In addition, BRILINTA is and has always been available via normal 
commercial distribution channels (i.e., wholesalers) since its U.S. 
launch. It has never had a restricted distribution program.

    Finally, more than 15 generic manufacturers have applied for 
regulatory approval from the FDA for the manufacture of generic 
ticagrelor and some, like Watson/Teva, have received tentative 
approvals from the FDA. Because conducting bioequivalence studies with 
the branded medicine is an FDA pre-approval requirement, it is clear 
that these generic manufacturers are not having difficulty accessing 
branded ticagrelor for their studies.

    In light of the context provided above, it is unclear why any 
generic manufacturer would be unable to obtain a sample of BRILINTA for 
their purposes or why an inquiry was lodged with the FDA related to 
this medicine.

    Question. Has AstraZeneca ever blocked access to samples?

    Answer. AstraZeneca is not aware of instances where the company has 
refused to sell samples or has otherwise blocked access to samples by 
generic manufacturers.

    Question. The Department of Health and Human Services' proposed 
rule, ``Fraud and Abuse; Removal of Safe Harbor Protection for Rebates 
Involving Prescription Pharmaceuticals and Creation of New Safe Harbor 
Protection for Certain Point-of-Sale Reductions in Price on 
Prescription Pharmaceuticals and Certain Pharmacy Benefit Manager 
Service Fees,'' envisions that drug manufacturers will offer up-front 
discounts rather than the back-end rebates that are now commonly 
provided. Some observers argue that a 1996 court case called into 
question whether manufacturers could offer up-front discounts, 
resulting in today's rebate-based system. I've heard differing opinions 
as to whether the issues related to the initial court case are still 
relevant.

    If the HHS proposed rule is finalized, can you assure the committee 
that your company will offer up-front discounts? If not, why?

    Answer. If the HHS proposed rule is finalized largely as proposed, 
AstraZeneca intends to comply with its requirements and use point-of-
sale discounts.

    Question. Please describe how you expect your company to respond to 
the HHS proposed rule to eliminate safe harbor protection for back-end 
rebates in Medicare Part D that is referenced above if it is finalized. 
Assuming you are confident that antitrust laws do not prevent your 
company from offering up-front discounts, specifically, do you envision 
that your company lowers the list price of a drug to the current after-
rebate net price, offer discounts equal to the current rebate amount, 
or a combination of both?

    Answer. Assuming the HHS rebate rule is finalized largely as 
proposed, AstraZeneca intends to comply with its requirements and use 
point-of-sale discounts. Our goal is to maintain net prices broadly in 
line with today, recognizing our ability to do so may be dependent on 
external factors and market response such as how plans evolve their 
benefit design and the total degree of transparency under the new 
model.

    AstraZeneca would plan to reduce list prices, pending reforms 
across all payers, including in the commercial sector in addition to 
Part D, as the current construct does not allow for two separate list 
prices (i.e., one list price for Part D and a different list price for 
the commercial sector). Therefore, we also support efforts to eliminate 
rebates in the commercial sector, and recommend that Congress explore 
such legislation. While eliminating rebates is an important step, 
benefit designs must also be evaluated.

    Question. To what extent are the back-end rebates your company 
currently offers contingent on the amount of market share realized for 
your drugs as a result of Part D plan formulary placement and other 
techniques?

    Answer. Our arrangements in Part D do not include a market share 
component.

    Question. Please provide a breakdown of percentage of sales that go 
to each payer (including Medicare, Medicaid, private pay, other) and a 
similar percentage by volume of the total number of each drug compared 
to total volume. Please provide this data for the most recent year 
available.

    Answer. Below you will find our estimated relative payer split of 
Gross Product Sales in the U.S., for the year ending December 31, 2018.

------------------------------------------------------------------------
       Total Products
-----------------------------   Sales $ Millions     Proportion of Total
            Payer                                         Business
------------------------------------------------------------------------
Medicaid                                 1,826,337                 11.0%
------------------------------------------------------------------------
Fed Gov't (VA, DOD, CDC,                 2,986,585                 18.1%
 PHS)
------------------------------------------------------------------------
GPO/LTC                                  1,362,663                  8.2%
------------------------------------------------------------------------
Commercial                               5,019,907                 30.4%
------------------------------------------------------------------------
Medicare Part D                          3,514,858                 21.3%
------------------------------------------------------------------------
Tricare                                     70,799                  0.4%
------------------------------------------------------------------------
Non-Contracted Sales/Other               1,756,851                 10.6%
------------------------------------------------------------------------
    Total                               16,538,000               100.0%
------------------------------------------------------------------------

    Question. Do your companies hire consultants or lobbyists to 
promote products at State Medicaid Pharmacy and Therapeutics 
Committees? To whom do you disclose advocacy activities surrounding 
State Medicaid programs, if at all?

    Answer. AstraZeneca does not utilize consultants or lobbyists to 
promote medicines at State Pharmacy and Therapeutics (P&T) Committees. 
However, AstraZeneca Medical Affairs personnel may engage in peer-to-
peer medical discussions with members of the medical community 
including Medicaid P&T committee members.

    AstraZeneca has comprehensive internal policies that oversee 
interactions between AstraZeneca employees and government officials. 
Federal and state laws and regulations also govern lobbying activities, 
and AstraZeneca complies with the attendant disclosure requirements.

    Question. Please describe how the costs of patient assistance 
programs are accounted for within your company's financial statements. 
Please also describe the types of market information, such as 
prescribing and use patterns, that your company collects from different 
types of patient assistance programs and patient hub services.

    Answer. AZ&MeTM Prescription Savings Program (Patient 
Assistance Program):

    In furtherance of its objective of ensuring patient access, 
AstraZeneca was one of the first manufacturers in the industry to 
establish a patient assistance program to facilitate access to certain 
medicines for uninsured and underinsured low-income patients. This 
program, known as AZ&Me, provides eligible patients with medicines at 
no cost.

    We account for the costs of medicines provided through the AZ&Me 
program as a component of our Operating Expenses.

    In connection with the AZ&Me program, AstraZeneca collects general 
program enrollment data such as number of patients in the program and 
medicine provided.

    Access 360TM (Patient Hub):

    AstraZeneca's patient hub, Access 360, is a reimbursement support 
program that provides patients and their healthcare providers with 
limited access and reimbursement support for AstraZeneca specialty care 
medicines. Access 360 collects patient, provider and payer coverage 
data in conjunction with appropriate patient opt-ins to administer the 
limited reimbursement services offered by the program.

    Question. Please provide a list of all contributions since January 
1, 2014, that your company has made to any tax exempt organizations 
working on issues related to drugs within your product lines, including 
but not limited to patient groups, disease awareness groups, medical or 
professional societies, universities or hospitals, industry 
associations or leagues. For each contribution, please provide the name 
of the organization that received the donation, the date the donation 
was made, the amount of the donation, and a description of the purpose 
of the contribution (i.e., was the contribution for the general fund, a 
specific purpose to a specific program, or continuing medical 
education). Please also note whether the contribution was unrestricted 
or restricted; if it was restricted, please explain all restrictions. 
Finally, if your company maintains a foundation or other separate 
charitable arm, please provide the name of all such entities, and list 
all donations made from that entity or entities.

    Answer. Our commitment to improving the lives of patients goes 
beyond our innovative medicines. We place significant value on 
collaboration and partnerships, including work done by non-profits, 
patient advocates, medical professionals, and researchers. To that end, 
we provide support for eligible programs through corporate 
contributions, research support, fellowships, and medical education 
grants. We also support conferences and initiatives for healthcare 
professionals and scientists.

    AstraZeneca believes in providing information to the public about 
our company, our medicines and about how we do business. In 2008, we 
began publishing biannual reports of our contributions to nonprofit 
organizations. We use contributions as our umbrella term for financial 
support to nonprofit organizations contributing to the public good 
(e.g., donations, sponsorships, and partnerships).

    The below data reflects the total value of contributions made by 
AstraZeneca to nonprofit organizations in the U.S. in the years 2014-
2018. A full list of contributions, including the recipient 
organization, associated program name, and amount of each contribution, 
can be found here: https://www.astrazeneca-us.com/sustainability/
Corporate-transparency/grants-and-contributions-disclosure.html.

          2018: $18.3 million

          2017: $5.5 million

          2016: $10.9 million

          2015: $19.8 million

          2014: $15.5 million

    In addition, in 1993, AstraZeneca founded the AstraZeneca 
HealthCare Foundation, a 501(c)(3) entity. The AstraZeneca HealthCare 
Foundation aims to promote public awareness surrounding healthcare 
issues, further public education and medical knowledge, and support 
charitable and qualified exempt organizations whose work aligns with 
the Foundation's charitable goals.

    In furtherance of AstraZeneca's commitment to improving health, in 
2010 the AstraZeneca HealthCare Foundation launched the Connections for 
Cardiovascular HealthSM (CCH) program. With the mission of 
improving cardiovascular health in the U.S., CCH awards grants to U.S.-
based nonprofit organizations whose work supports CCH's mission. Since 
its launch, CCH has awarded nearly $23 million to 52 organizations 
working to prevent cardiovascular disease.

    The below data reflects the approximate total value of grants made 
by CCH per year between 2014 and 2018. A full list of grants, including 
the recipient organization, associated program name, and amount of each 
contribution, can be found here: https://www.astrazeneca-us.com/
sustainability/healthcare-foundation/connections-for-cardiovascular-
health.html#past-grant-awardees--0.

          2018: $1.2 million

          2017: $993,880

          2016: $1.8 million

          2015: $1.9 million

          2014: $2.6 million

    AstraZeneca also awards medical education grants and scientific 
sponsorships. These grants are offered to support independent medical 
education, scientific sponsorships, and fellowship or healthcare 
professionalin-training. Grants are offered for conduct of programs, 
are awarded on the basis of individual applications through our medical 
education grants process, and are not conditioned on services. This 
process and all grant decisions are managed independently within our 
Medical Affairs group and have no connection to our sales and marketing 
departments.

    The below data reflects the approximate total value of medical 
education grants made by AstraZeneca per year, since 2014. A full list 
of medical education grants offered to non-profit organizations, 
including the recipient organization, associated program name, date, 
and amount of each contribution, can be found in Appendix A.

          2018: $28.9 million

          2017: $17.5 million

          2016: $11.6 million

          2015: $24.9 million

          2014: $14.8 million

    Question. Pay-for-delay agreements cost consumers and taxpayers 
billions in higher drug costs every year. The FTC has gone after drug 
companies that enter into these settlements where the brand pays the 
generic company to keep its lower cost alternative off the market. I'm 
the lead Republican sponsor of S. 64, the Preserve Access to Affordable 
Generics and Biosimilars Act, which would help put an end to these 
deals.

    Do you agree that these pay-off agreements keep drug costs high for 
patients because they delay competition?

    Answer. AstraZeneca has confidence in patents that protect our 
medicines and, where appropriate, we file lawsuits to protect our 
intellectual property.

    AstraZeneca does not enter into ``pay-off agreements,'' if those 
are understood to include settlements that pay generic competitors to 
delay entry into the market. AstraZeneca engages in patent settlements 
but we do not believe these resolutions contribute to increased prices. 
In the absence of a settlement, a generic would not necessarily prevail 
in the patent litigation and therefore would not be able to enter the 
market. Indeed, AstraZeneca has entered into many early-entry patent 
settlements that allow generic manufacturers to license innovator 
patents and thereby permit generic competition before expiration of 
AstraZeneca's patent rights.

    Settlement agreements that permit entry of generic drugs before 
expiration of relevant patent rights do not stifle competition but 
instead permit early entry by resolving patent disputes that would 
otherwise prevent generic alternatives to branded medication.

    All of AstraZeneca's patent settlements fully comply with the law. 
These settlements provide increased clarity and stability to both 
parties, allowing innovators like AstraZeneca to continue investing 
substantially in new medicines for patients and frequently allowing 
generic competitors to enter the market before expiration of 
AstraZeneca's patent rights.

    Question. Has your company ever entered into these kinds of 
settlements with a generic company?

    Answer. AstraZeneca does not enter into settlements that pay 
generic competitors to delay entry into the market.

    Question. Do you support the pay for delay bill?

    Answer. While AstraZeneca supports efforts to curb patent 
settlement abuses, we have concerns about the Preserve Access to 
Affordable Generics and Biosimilars Act in its current form. For 
example, the proposed legislation would be retroactive to 2013 and 
would unfairly subject to potential scrutiny lawful settlements entered 
into based on the then existing legal construct. As a general matter, 
AstraZeneca believes that patent settlement agreements are pro-
competitive because they can permit entry of generic drugs before 
expiration of relevant patent rights.
                           rebate traps/walls
    Question. I'm increasingly concerned about the effect of so-called 
``rebate traps'' or ``rebate walls'' on patients' access to quality, 
lower cost medicine. I understand there is ongoing litigation 
challenging these practices as anti-competitive.

    Does your company engage in the bundling of rebates over multiple 
products? If so, why? And what benefit does the consumer gain from 
that?

    Answer. AstraZeneca offers portfolio discount arrangements to 
improve patient access and affordability across multiple medicines, 
thus ensuring the right medicine can be prescribed for the right 
patient. Portfolio discounting allows manufacturers and plans another 
mechanism to negotiate for formulary access for the patient, in 
addition to single-medicine discounts and rebates. Irrespective of the 
approach to discounting, AstraZeneca also ensures discounts are 
appropriately reported in government price reporting metrics (e.g., 
Best Price, Average Manufacturer Price, and Average Sales Price).

    Question. Does your company view these practices as anticompetitive 
or harmful to patients' access to quality, lower cost medicine?

    Answer. AstraZeneca does not view these practices as 
anticompetitive or harmful to patients' access. In fact, AstraZeneca 
offers portfolio discount arrangements to improve patient access and 
affordability.

    Question. If a policy were adopted to eliminate rebates, or to 
require that rebate savings be passed on to the consumer, would that in 
and of itself solve the issue of rebate ``traps'' and ``walls''? And 
would consumers benefit from such a policy?

    Answer. AstraZeneca believes that evolving the current system of 
paying for and delivering drug therapies to one in which patients more 
directly benefit from the discounts and rebates that AstraZeneca 
provides is an important step towards improving affordability and 
supporting innovation. This can best be accomplished by eliminating 
rebates in Medicare Part D and the commercial sector, which would 
create competition between manufacturers on net price instead of rebate 
amounts, thereby helping to eliminate rebate ``traps'' and ``walls.''

    AstraZeneca also believes that patient cost-sharing should be more 
aligned to a medicine's net price, and that eliminating rebates and 
moving to a point-of-sale discount model should help accomplish this 
goal. Additionally, it is important to note that lowering list prices 
in the U.S. without addressing broader challenges, including benefit 
design, will not improve affordability for many patients. While 
eliminating rebates is an important step, benefit designs must also be 
evaluated.
                              drug pricing
    Question. When setting the list price of a drug, does your company 
consider regulatory costs or compliance? If so, how specifically do 
those factors affect the list price of a drug? Please provide at least 
one specific example, if applicable, from your current product 
portfolio.

    Answer. AstraZeneca does not directly consider regulatory or 
compliance costs when setting the list price of a drug. AstraZeneca's 
approach to pricing across all medicines is driven by a number of 
factors, including clinical value, patient access and affordability, 
patient population, government and payer coverage requirements, RandD 
expenditures, manufacturing costs, and competitive dynamics. 
AstraZeneca is mindful of healthcare costs and is continuously 
exploring innovative opportunities and solutions to deliver medicines 
while considering cost and value. In setting drug prices, AstraZeneca 
takes into account both the budget impact to payers (including Medicare 
and pharmacy benefit managers (PBMs)) as well as patient out-of-pocket 
costs to maintain patient access to needed medication. AstraZeneca has 
also been a leading innovator in developing alternate payment 
structures for its medicines. In particular, AstraZeneca has emphasized 
value-based agreements, which, broadly speaking, seek to link access, 
reimbursement or price, to a demonstrated clinical benefit or outcome.

    Question. When setting the list price of a drug, does your company 
consider the risk of liability or litigation? If so, how specifically 
do those factors affect the list price of a drug? Please provide at 
least one specific example, if applicable, from your current product 
portfolio.

    Answer. AstraZeneca does not consider the risk of liability or 
litigation when setting the list price for a particular drug.

                                 ______
                                 
                Questions Submitted by Hon. Pat Roberts
    Question. What role do you see value-based arrangements (VBAs) 
playing in the effort to reduce prescription drug costs? What potential 
do these arrangements have to find the ``sweet spot'' between 
controlling costs to patients and encouraging innovation of new drugs?

    Answer. We believe medicines are part of the solution to 
controlling health-care costs. They not only improve patient outcomes 
and increase quality of life, but also reduce downstream costs. Value-
based agreements allow us to reimburse the health-care system if our 
medicines do not deliver as intended. This solution demonstrates our 
willingness to stand behind the value of our medicines.

    AstraZeneca is working closely with payers and health systems to 
explore innovative solutions to improve access and affordability that 
demonstrate the value our medicines bring to patients and the health-
care system. Our value-based agreements aim to manage the totality of 
treatment costs and keep people healthy and out of the hospital. For 
several years, AstraZeneca has been exploring these types of solutions 
through value-based agreements where we are willing to work with 
health-care stakeholders to tie payment to patient outcomes.

    To date, we have entered into approximately 40 value-based 
agreements across our therapeutic areas with a variety of payers, 
making AstraZeneca a leader in the field of value-based agreements.

    As an example, and as noted in the written testimony submitted to 
the Senate Committee on Finance, AstraZeneca agreed with Express 
Scripts that for IRESSA, an oral treatment for certain types of lung 
cancer, we will fully reimburse Express Scripts for discontinued use 
before the third fill, including if discontinuation occurs because 
patients did not respond to treatment.

    Question. How can VBAs help lower what patients pay out-of-pocket?

    Answer. While most of these agreements have been focused on 
securing patient access to our medicines and delivering better patient 
outcomes, where payers are willing, we are also looking to more 
directly address patient out-of-pocket affordability through these 
innovative arrangements.

    Our ambition is that these agreements will evolve to enable 
reimbursement back to a payer to be shared with the patient when 
medicines do not perform as expected.

    As an example where a value-based agreement directly reduced out-
of-pocket costs for patients, we recently announced the initiation of a 
value-based agreement for University of Pittsburgh Medical Center 
(UPMC) Medicare patients who are prescribed BRILINTA. This value-based 
contract, which was effective as of January 1, 2019, is groundbreaking 
in two ways. First, the contract lowers the out-of-pocket costs for a 
UPMC Medicare Part D patient to approximately $10 for a 30-day supply. 
Second, what UPMC pays for BRILINTA will vary based on patient 
outcomes, tying the cost of the medicine to its real-world clinical 
performance.

    We are currently exploring another value-based agreement in 
Medicare Part D. In addition to having a significant outcomes-based 
component, this arrangement would reduce patient out-of-pocket costs. 
This type of agreement allows patients to access their medicines at a 
lower out-of-pocket cost and payers to control their overall healthcare 
costs through paying for outcomes.

    Question. Can Congress do more to allow for and encourage the use 
of VBAs?

    Answer. We believe that there are steps the government can take to 
address challenges and help encourage the timely adoption of value-
based agreements, including in public sector programs like Medicare.

    For example, at this time, the current Anti-Kickback Safe Harbor 
(AKS) regulations do not expressly address value-based agreements. 
Accordingly, manufacturers must seek to structure value-based 
agreements to meet the requirements of existing safe harbors from the 
AKS, such as the discount safe harbor and personal services safe 
harbor, that were created for purposes other than value-based 
agreements. Although we believe that value-based agreements can 
strongly benefit patients and the health-care system overall, the lack 
of clarity in application of the safe harbors to value-based agreements 
creates regulatory uncertainty that discourages broader implementation 
of value-based agreements in public-sector programs.

    In addition to the risk of AKS liability, value-based agreements 
present other regulatory challenges that manufacturers must navigate. 
For example, manufacturers must manage complex government price 
reporting calculations that may not account for price fluctuations over 
time that may be associated with a value-based agreement.

    In a future system, the default approach should be that pricing and 
reimbursement for drug therapies are tied to patient outcomes and the 
value the particular therapy provides. As such, it is imperative that 
manufacturers and payers--including Medicare plans--engage in value-
based agreements similar to the IRESSA and BRILINTA examples referenced 
previously.

    Policies to encourage these arrangements and to reduce or eliminate 
existing challenges will be essential to their long-term success. To 
that end, AstraZeneca appreciates the support of Senators Warner and 
Cassidy for value-based agreements, as demonstrated by their requests 
for input on the Patient Affordability Value and Efficiency (PAVE) Act. 
This draft legislation would promote the development of value-based 
agreements by offering increased flexibility for manufacturers to enter 
into such arrangements, including with Medicare Part D plans by 
addressing AKS and government pricing concerns.

    This legislation is particularly important given the 
administration's proposal to eliminate PBM rebates under the discount 
safe harbor. Currently, many value-based agreements are structured 
using a rebate agreement, under which the terms of a discount are based 
on clinical or cost outcomes measures. Therefore, the elimination of 
discount safe harbor protection for rebates without an exception for 
value-based agreements could inadvertently reduce incentives for value-
based agreements, which we do not believe is the administration's 
intent. We have therefore recommended to HHS that value-based 
agreements are exempt from the proposed changes to the discount safe 
harbor and we encourage members of Congress to support this exemption.

    Through the partnership of payers and policymakers, we look forward 
to a future where implementation of value-based agreements across 
public and private payers is widespread.

                                 ______
                                 
                Questions Submitted by Hon. John Cornyn
    Question. We continue to hear that rebates negotiated off of the 
list price of a drug are both good and bad. Pharmacy benefit managers 
and plans have argued that rebates are used to lower premiums across 
the board and that it is the best way to seek a price concession on 
otherwise expensive drugs. Your industry argues that these payers are 
insisting on higher rebates that can only be achieved by raising list 
prices. But patients often lose under this system, with out of pocket 
costs being tied to list price. Insulin patients appear to be routinely 
impacted by this perversity in the system.

    Please explain to the committee how your company would reduce list 
prices if rebates were no longer a part of the equation?

    Answer. Assuming the HHS rebate rule is finalized largely as 
proposed, AstraZeneca intends to comply with its requirements and use 
point-of-sale discounts. Our goal is to maintain net prices broadly in 
line with today, recognizing our ability to do so may be dependent on 
external factors and market response such as how plans evolve their 
benefit design and the total degree of transparency under the new 
model.

    AstraZeneca would plan to reduce list prices, pending reforms 
across all payers, including in the commercial sector in addition to 
Part D, as the current construct does not allow for two separate list 
prices (i.e., one list price for Part D and a different list price for 
the commercial sector). Therefore, we also support efforts to eliminate 
rebates in the commercial sector, and recommend that Congress explore 
such legislation. While eliminating rebates is an important step, 
benefit designs must also be evaluated.

    Question. What assurance can you provide that you would in fact 
lower your prices?

    Answer. Assuming the HHS rebate rule is finalized largely as 
proposed, AstraZeneca intends to comply with its requirements and use 
point-of-sale discounts. Our goal is to maintain net prices broadly in 
line with today, recognizing our ability to do so may be dependent on 
external factors and market response such as how plans evolve their 
benefit design and the total degree of transparency under the new 
model.

    AstraZeneca would plan to reduce list prices, pending reforms 
across all payers, including in the commercial sector in addition to 
Part D, as the current construct does not allow for two separate list 
prices (i.e., one list price for Part D and a different list price for 
the commercial sector). Therefore, we also support efforts to eliminate 
rebates in the commercial sector and recommend that Congress explore 
such legislation. While eliminating rebates is an important step, 
benefit designs must also be evaluated.

    Question. What actions should be taken to ensure that patients are 
actually seeing the benefits of lower out-of-pocket costs?

    Answer. In the absence of rebates, the market incentives for the 
differential between list and net price should be reduced because 
manufacturers will be competing on the basis of net price instead of 
rebate amounts. Because Part D patient cost-sharing is currently based 
on list price and not net price, this change may also result in lower 
cost-sharing for patients. Additionally, it is important to note that 
lowering list prices in the U.S. without addressing broader challenges, 
including benefit design, will not improve affordability for many 
patients. While eliminating rebates is an important step, benefit 
designs must also be evaluated.

    AstraZeneca also supports monthly and annual out-of-pocket caps in 
Medicare Part D to further ensure that patients see the benefits of 
lower out-of-pocket costs.

    Question. If rebates are driving high list prices for drugs as drug 
manufacturers' claim, why do you think that Part B drugs, which have no 
PBM rebates, are also seeing significant price increases? Whose fault 
is that?

    Answer. For our Part B products, price increases are modest and 
generally in line with inflation. We are supportive of competition, 
including policies that support more widespread use of biosimilars.

                                 ______
                                 
                Questions Submitted by Hon. Steve Daines
    Question. As an advocate for improving Montanans' access to low-
cost medications, I've been a champion of the Creating and Restoring 
Equal Access to Equivalent Samples (CREATES) Act, which would combat 
anticompetitive practices used by some brand-name pharmaceutical 
companies to block or delay competing generic drugs from entering the 
market. During the hearing when I asked if your company had ever 
withheld samples from generic manufacturers, you answered emphatically 
no. Yet, according to the Food and Drug Administration (FDA), generic 
drug makers have made inquiries with the agency claiming they were 
unable to access samples provided by Pfizer and AstraZeneca that are 
needed to conduct studies to produce low-cost generic drugs.

    Do you agree that denying generic drug manufacturers access to 
samples keeps drug costs high for patients due to lack of competition?

    Answer. AstraZeneca is supportive of allowing generic manufacturers 
to have access to samples.

    Question. Has your company refused to sell samples or placed any 
barriers in the way of generic drug makers acquiring samples?

    Answer. AstraZeneca is not aware of instances where the company has 
refused to sell samples or has otherwise blocked access to samples by 
generic manufacturers.

    Question. Are you aware of any outstanding requests for samples?

    Answer. AstraZeneca is not aware of any unanswered, delayed, or 
outstanding requests for samples of our medicines by generic 
manufacturers.

    It is our understanding that one of our medicines, BRILINTA, was 
included on the Reference Listed Drug Access Inquiries List (RLD List) 
based on a single inquiry received by the FDA. However, BRILINTA has 
always been available via normal commercial distribution channels 
(i.e., wholesalers) and has never had a restricted distribution 
program.

    Unfortunately, the RLD List does not identify the company that 
reportedly requested information (or samples) from AstraZeneca, the 
date the information was requested, or any other information that would 
allow AstraZeneca to better understand or further investigate the 
circumstances of this inquiry. On its website, the FDA does advise that 
it has ``not independently investigated or confirmed the access 
limitations described in the inquiries received.'' Given this 
limitation, the listing of an inquiry on the RLD List does not mean 
that the FDA has in fact determined that access to samples by generic 
manufacturers was limited or withheld for the medicines identified. 
Indeed, based on our internal review, we have not identified any 
circumstances that substantiate the inquiry received by the FDA 
relating to BRILINTA.

    Question. How does your company work to prevent abuses in the 
sample system?

    Answer. AstraZeneca is supportive of allowing generic manufacturers 
to have access to samples and is not aware of instances that would be 
considered abuse of the samples system.

                                 ______
                                 
                 Questions Submitted by Hon. Todd Young
         re-evaluating business strategies in foreign countries
    Question. Since taking office, President Trump has made reducing 
drug prices one of his highest priorities--and has repeatedly spoken 
about his frustration with the U.S. subsidizing the costs of 
pharmaceuticals for the rest of the world. He has gone so far as to 
issue proposals, like the International Pricing Index (IPI) Model, in 
an attempt to bring down prescription drug prices. With the increased 
scrutiny of the industry and of the drug supply chain as a whole in the 
United States, have any of your companies re-evaluated your business 
strategy in foreign countries?

    Answer. We continuously evaluate our business approaches in all 
markets and adjust our strategies accordingly based on many factors, 
including the overall environment.

    Question. If not, then why?

    Answer. See response above.

    Question. If a proposal, like IPI, were implemented, would it force 
your companies to potentially ``walk away from the negotiating table 
when other countries demand low prices subsidized by America's 
seniors,'' as HHS Senior Advisor for Drug Pricing Reform John O'Brien 
has said?

    Answer. If the IPI model were put into effect as proposed, where an 
identified average international price would be derived from 16 
countries, this would impact our ability to sell our medicines in some 
of the identified markets.

    The IPI model was issued as an Advanced Notice of Proposed 
Rulemaking (ANPRM). Important details such as the medicines that would 
be included in the model, the final list of nations included as 
reference countries, and the timing of reimbursement changes are still 
unknown. We look forward to engaging with policymakers on this 
proposal.

    Question. What are some of your ideas on how we can ensure 
Americans aren't shouldering the full cost of pharmaceuticals?

    Answer. We agree that out-of-pocket costs are unsustainable in the 
U.S., but the answer is not to move to a system found in other 
countries or to link pricing in the U.S. to the International Pricing 
Index.

    It is critical to recognize that while price controls are the 
default in many other countries, these price controls result in reduced 
access to important medicines. In the 16 countries referenced in the 
International Pricing Index model proposal, only 55 percent of new 
cancer medicines are available, compared to 96 percent in the U.S. In 
those countries, it also takes more than a year longer for the 
medicines to become available and this can have significant impacts on 
patients. For example, in 2018, the Food and Drug Administration (FDA) 
and the European Medicines Agency (EMA) approved a new indication for 
LYNPARZA for ovarian cancer. However, the U.K.'s National Institute for 
Health and Care Excellence (NICE) has not recommended that the U.K.'s 
National Health System (NHS) reimburse for LYNPARZA in this indication, 
resulting in limited access for patients in the U.K.

    Instead of international reference pricing, we should focus on 
market-based solutions. We believe that there are several steps that 
lawmakers can take to ensure that drug prices are affordable for 
Americans, while ensuring that innovation in the biopharmaceutical 
sector can continue to flourish in the U.S. Our suggestions fall in 
five main categories, described in more detail below:

          Rebate Reform: The current pharmacy benefit manager (PBM) 
        rebate system does not fully benefit patients and has resulted 
        in a lack of transparency across the supply chain. We support 
        the current proposed rule to eliminate rebates in Medicare Part 
        D and Medicaid managed care. We also support efforts to 
        eliminate rebates in the commercial sector as well, which will 
        likely require legislation. We therefore recommend that 
        Congress explore legislation that would eliminate rebates in 
        the commercial market.

          Value-Based Agreements: As described in detail in our 
        written testimony to the Senate Committee on Finance hearing, 
        we are also working closely with payers and health systems to 
        explore innovative solutions to improve access and 
        affordability that demonstrate the value our medicines bring to 
        patients and the health-care system. For several years, 
        AstraZeneca has been exploring these types of solutions through 
        value-based agreements where we are willing to work with 
        health-care stakeholders to tie payment to patient outcomes. To 
        date, we have entered into approximately 40 value-based 
        agreements across our therapeutic areas with a variety of 
        payers, making AstraZeneca a leader in the field of value-based 
        agreements.

           We believe that there are steps the government can take to 
        address certain regulatory challenges to the broader 
        implementation of value-based agreements and help encourage the 
        timely adoption of value-based agreements, including in public-
        sector programs like Medicare. To that end, AstraZeneca 
        appreciates the support of Senators Warner and Cassidy for 
        value-based agreements, as demonstrated by their requests for 
        input on the Patient Affordability Value and Efficiency (PAVE) 
        Act. This draft legislation would promote the development of 
        value-based agreements by offering increased flexibility for 
        manufacturers to enter into such arrangements, including with 
        Medicare Part D plans.

          Biosimilars: We also encourage Congress to consider policies 
        to encourage greater use of biosimilars in the U.S. We believe 
        that competition is a key component to reducing costs, and that 
        is why we support expanded use of biosimilars in the U.S. As a 
        global company, we operate in countries, particularly those in 
        the European Union, where biosimilar competition is 
        particularly robust. We support a similarly vigorous 
        biosimilars market in the U.S.

           We therefore appreciate the efforts of the FDA to increase 
        the availability of biosimilars in the U.S., including the 
        FDA's development of a Biosimilars Action Plan. We support 
        efforts to streamline and improve the efficiency of the 
        biosimilars approval pathway for the benefit of patients. Such 
        efforts could include increased transparency into the patents 
        applicable to biologic medicines.

           We also support cost-sharing and reimbursement policies that 
        facilitate the uptake of biosimilars. Such policies include 
        Medicare reimbursement rates that ensure that biosimilars can 
        compete on equal footing with innovator medicines, and 
        reductions to cost-sharing amounts for biosimilars.

          Out-of-Pocket Caps for Medicare Patients: In the commercial 
        market, it is common for patients to have a cap on total out-
        of-pocket amounts. However, such a construct does not exist in 
        the Medicare program. Because of the way the Part D benefit is 
        designed, for example, cost-sharing can be particularly high in 
        the first months of the plan year and/or in the first months of 
        therapy. A recent study found that rates of prescription 
        abandonment and delayed initiation of oral cancer therapies 
        increase as cost-sharing amounts rise. Such a result reflects 
        the need for a restructuring of the current benefit design, 
        which could be accomplished by establishing a monthly or annual 
        out-of-pocket cap. This would give patients greater certainty 
        in the total amount of out-of-pocket costs they could face.

          Transparency: We support greater transparency across the 
        biopharmaceutical supply chain, which includes greater 
        transparency into drug pricing. To that end, we generally 
        support the policies included in the current versions of the 
        SPIKE and C-THRU Acts. There are a variety of State-level drug 
        pricing transparency laws and regulations. We believe that 
        having a consistent, Federal standard for drug pricing 
        transparency requirements, like those included in the SPIKE 
        Act, should pre-empt state transparency laws to reduce 
        confusion and compliance burden.

           We also support transparency efforts to ensure that patients 
        and prescribers have meaningful information on out-of-pocket 
        costs at the point of prescribing, so that they can make 
        informed decisions about the most appropriate and affordable 
        therapy.
              foreign countries' pricing and reimbursement
    Question. President Trump and Secretary Azar have both repeatedly 
described their frustrations with ``foreign freeloading'' of U.S. drugs 
in the last year. ``When foreign governments extort unreasonably low 
prices from U.S. drug makers, Americans have to pay more to subsidize 
the enormous cost of research and development. . . . It's unfair and 
it's ridiculous, and it's not going to happen any longer.''

    Do you agree that because of foreign countries' pricing and 
reimbursement systems, U.S. patients and innovators are shouldering the 
burden for financing edical advances?

    Answer. We agree that many foreign countries' pricing and 
reimbursement systems do not adequately recognize innovation in the 
biopharmaceutical sector. In many other countries, the government 
utilizes price controls for drug therapies, and in many cases these 
price controls result in reduced or delayed access to therapy for 
patients in those countries. The U.S. benefits from an open-market 
system that supports competition and innovation and accordingly 
Americans place high value on both choice and access to the latest 
medicines. For patients in the U.S., it is not a question of when an 
important treatment will be available, but rather how they will access 
that medicine. It is in this context that AstraZeneca continues to 
engage with other stakeholders regarding possible solutions and 
specific actions that can be taken to address pricing concerns, which 
we describe in greater detail in our written testimony. These 
approaches must balance the need to improve access and affordability 
while fostering innovation. Pricing controls as well as access and 
reimbursement practices in other countries are a challenge.

    Question. How do foreign countries' pricing and reimbursement 
systems affect our prescription drug costs?

    Answer. We do not take into account foreign market pricing in 
setting U.S. prices.

    Question. Are foreign governments taking note of the concerns being 
raised by the Trump administration and have they responded in any way?

    Answer. While these matters have been widely reported on globally, 
we do not have insights into actions being taken by other health 
authorities directly in response to the Trump administration's efforts 
in this area.

    Question. Has there been any noticeable change in any of our trade 
agreements since these concerns have been raised by the Trump 
administration?

    Answer. AstraZeneca and the biopharmaceutical industry have 
consistently advocated for trade agreements that support strong 
intellectual property rights and protect market access. We believe our 
trade partners should be fair and transparent so that patients around 
the world can benefit from U.S. innovation.
                  medicaid closed formulary proposals
    Question. In an attempt to bring down drug costs, various States 
have been exploring whether to exclude certain drugs from its Medicaid 
program. For example, the State of Massachusetts recently asked CMS for 
permission to create a closed formulary where the State Medicaid 
program would pick at least one drug per therapeutic class. CMS denied 
their waiver request citing violation of Federal law, but this proposal 
does bring up important questions on how to contain drug prices in 
State Medicaid programs.

    If the principles of the Medicare Part D program--including the 
necessary patient protections--were applied to State Medicaid programs, 
do you think it [would] lower drugs costs while ensuring access to 
patients?

    Answer. Under the current construct in Medicaid, manufacturers 
provide mandatory rebates and in turn, States are required to cover all 
of the manufacturer's drugs. This ensures that Medicaid patients have 
access to the full range of available therapies. We support increased 
flexibility for State Medicaid agencies in managing their Medicaid 
programs, but only so long as there are robust protections that ensure 
that Medicaid patients can continue to access the medicines they need.
                        medicaid ``best price''
    Question. In the Trump administration's Blueprint, they suggested 
that because drug manufactures have to give Medicaid the ``best price'' 
on drugs, there is no incentive to offer deeper discounts to other 
payers--both government and commercial--than what is already offered 
under the Medicaid Drug Rebate Program.

    Does the Medicaid ``best price'' requirement encourage 
manufacturers to increase initial prices?

    Answer. We do not believe that the Medicaid Best Price requirement 
encourages manufacturers to increase their initial list price. However, 
the requirement does impact decisions regarding the size of rebates and 
discounts offered in the commercial sector because setting a new Best 
Price can result in significantly increased Medicaid rebate and 340B 
liability. Additionally, manufacturers may be hesitant to offer very 
aggressive value-based agreements due to the risk of setting a new Best 
Price.

    Question. What, if any, changes would you suggest we make to the 
program?

    Answer. We recommend an exemption from Best Price for value-based 
agreements, which is a policy included in Senator Grassley's and 
Senator Warner's draft version of the PAVE Act.
                        outcomes-based contracts
    Question. In almost all of your testimonies, you highlight your 
support of outcomes-based contracts and how we need to be shifting our 
system toward that approach.

    How will these contracts lower drug costs for patients in both the 
near term and long-term?

    Answer. While most value-based agreements have been focused on 
securing patient access to our medicines and delivering better patient 
outcomes, where payers are willing, AstraZeneca is also looking to more 
directly address patient out-of-
pocket affordability through these innovative arrangements.

    As an example, we recently announced the initiation of a value-
based agreement for University of Pittsburgh Medical Center (UPMC) 
Medicare patients who are prescribed BRILINTA. This value-based 
contract, which was effective as of January 1, 2019, is groundbreaking 
in two ways. First, the contract lowers the out-of-pocket costs for a 
UPMC Medicare Part D patient to approximately $10 for a 30-day supply. 
Second, what UPMC pays for BRILINTA will vary based on patient 
outcomes, tying the cost of the medicine to its real-world clinical 
performance.

    We are currently exploring another value-based agreement in 
Medicare Part D. In addition to having a significant outcomes-based 
component, this arrangement would reduce patient out-of-pocket costs. 
This type of agreement allows patients to access their medicines at a 
lower out-of-pocket cost and payers to control their overall healthcare 
costs through paying for outcomes.

    Question. How will they lower overall health-care costs for our 
Federal programs?

    Answer. We believe medicines are part of the solution to 
controlling health-care costs. They not only improve patient outcomes 
and increase quality of life, but also reduce downstream costs. Value-
based agreements have the potential to increase efficiencies in the 
health-care system, including government programs, by ensuring that 
payment is based on value rather than reimbursement based on volume. 
These agreements support patients receiving the most appropriate 
treatment, ensure appropriate patient behaviors and, most importantly, 
tie reimbursement to improved patient outcomes.

    In many cases value-based agreements encourage a focus on important 
patient behaviors such as adherence and persistence as well as improved 
emphasis on patient education to promote healthier lifestyles and 
choices. These agreements broaden payer focus to the total cost of care 
and quality outcomes. It is important that we look at all aspects 
related to the cost of care to find efficiencies that drive greater 
value in the health-care system. These opportunities exist in both the 
commercial and government sectors.

    We support value-based agreements because they allow us to 
reimburse the health-care system if our medicines do not deliver as 
intended. This solution demonstrates our willingness to stand behind 
the value of our medicines.

    Through the partnership of payers and policymakers, we look forward 
to a future where implementation of value-based agreements across 
public and private payers is widespread.

    Question. What have the preliminary results looked like so far?

    Answer. We are frequently asked if we have ever had to ``pay out'' 
on a value-based agreement, and the answer is ``yes.'' For example, we 
have entered into an agreement for one of our oncology medicines with a 
large payer. We have reimbursed the payer for more than 20 percent of 
patients on that medicine. Of course, we also have examples where we 
have seen the medicine perform as well or better than our clinical 
data. This is good for patients and good for the payer and health 
system overall in that, by providing access to that medicine, they have 
seen improved patient outcomes.
                       transparency/point of sale
    Question. In almost all of your testimonies, you express your 
support for the Trump administration's proposal to allow manufacturers 
to provide PBMs up-front discounts that are passed onto patients at the 
point of sale.

    Do you feel like this proposal will make the transactions within 
the drug supply chain more transparent?

    Answer. Yes, the Trump administration's rebate proposal should make 
transactions more transparent because cost-sharing will reflect point-
of-sale discounts and, therefore, net prices. We encourage the 
administration and Congress to closely assess the impact of such 
increased transparency on patients and the biopharmaceutical supply 
chain more broadly.

    Question. If so, would this transparency bring down drug costs--
overall and for specialty drugs?

    Answer. In general, we believe that increased transparency due to 
point-of-sale discounts will in turn lead to greater competition and 
reduced costs overall. However, the impact of transparency on the 
prices of specific drugs will vary based on the competitive landscape 
for that medicine.
         the relationship between wholesalers and manufacturers
    Question. When talking about the pharmaceutical supply chain, a lot 
of focus has been placed on the pharmacy benefit manager. But there's 
another side of the equation that I'd like to ask about. How do 
wholesalers negotiate pricing with manufacturers?

    Answer. In general, wholesalers do not negotiate pricing with 
manufacturers. Wholesalers receive service fees from manufacturers for 
bona fide services they provide.

    Question. What impact does this have on drug costs?

    Answer. In general, wholesalers do not negotiate pricing with 
manufacturers.

    Question. What incentives or disincentives do they have to contain 
price increases?

    Answer. Wholesalers receive service fees from manufacturers for 
bona fide services they provide. Certain fees across the supply chain--
including with wholesalers--are based on a percentage of the list 
price. We support efforts to ``de-link'' such fees from the list price 
across the supply chain, as this would align incentives across the 
supply chain to lower prices.

                                 ______
                                 
                 Questions Submitted by Hon. Ron Wyden
                          proposed rebate rule
    Question. As has been done in many other settings, drug 
manufacturers said during the hearing that one reason list prices for 
drugs are high is that pharmaceutical benefit managers (PBMs) demand 
larger and larger rebates in order for the drug to receive favorable 
placement on a formulary. You and your colleagues who testified during 
the hearing stated if the administration's proposal on changes to the 
anti-kickback safe harbor for pharmaceutical rebates took effect, your 
company would likely lower list price. Like many Oregonians, I am 
skeptical drug manufacturers would voluntarily lower their prices.

    Therefore, would you support legislation that would (1) make 
similar changes the administration has put forward related to Part D 
and Medicaid managed care, (2) change the rebate system in a similar 
way to the proposal for the commercial market, and (3) require drug 
makers to lower the list price of their drugs equal to the amount of 
rebates provided today?

    Answer. Assuming the HHS rebate rule is finalized largely as 
proposed, AstraZeneca intends to comply with its requirements and use 
point-of-sale discounts. Our goal is to maintain net prices broadly in 
line with today, recognizing our ability to do so may be dependent on 
external factors and market response such as how plans evolve their 
benefit design and the total degree of transparency under the new 
model.

    AstraZeneca would plan to reduce list prices, pending reforms 
across all payers, including in the commercial sector in addition to 
Part D, as the current construct does not allow for two separate list 
prices (i.e., one list price for Part D and a different list price for 
the commercial sector). Therefore, we also support efforts to eliminate 
rebates in the commercial sector and recommend that Congress explore 
such legislation. While eliminating rebates is an important step, 
benefit designs must also be evaluated.
                      medicaid drug rebate program
    Question. The Medicaid Drug Rebate Program (MDRP) requires 
manufacturers to provide a basic rebate and an additional inflationary 
rebate for both brand and generic drugs. The inflationary rebate is an 
increasingly substantial part of total rebates due in large part to 
large increases in drug prices that exceed inflation. Under current 
law, this inflationary rebate is capped at 100 percent of Average 
Manufacturer Price (AMP). This is the case even when manufacturers 
continue to raise their prices well above inflation.

    Please provide a list of all of your pharmaceutical products that 
have reached the Medicaid AMP rebate cap in any of the 20 quarters from 
January 1, 2014 through December 31, 2018.

    Answer. Please see Appendix B.

    Question. For each drug listed in response to question 1, please 
also provide a list of which quarters and years each drug hit the cap.

    Answer. Please see Appendix B.
                medicaid drug rebate program compliance
    Question. I am concerned about recent reports and legal settlements 
surrounding drug manufacturers' failure to comply fully with the 
requirements of the MDRP. For example, an analysis by the U.S. 
Department of Health and Human Services Office of Inspector General 
found that between 2012 and 2016 taxpayers may have overpaid by as much 
as $1.3 billion for 10 potentially misclassified drugs. That is why I 
introduced the Right Rebate Act with Chairman Grassley to prevent drug 
manufacturers from manipulating Medicaid to increase their profits. 
However, I continued to be concerned about oversight and manufacturer 
compliance with the requirements of the Medicaid Drug Rebate Program.

    Accordingly, please describe the following:

    Your company's current compliance plan and procedures used to 
ensure compliance with the requirements of the Medicaid Drug Rebate 
Program including internal audits or other checks you use to identify 
compliance vulnerabilities.

    Answer. All aspects of AstraZeneca's compliance with the 
requirements of the Medicaid Drug Rebate Program, including Statutory 
Pricing (average manufacturer price (AMP) and Best Price) and Medicaid 
Rebate payments, are covered by AstraZeneca's compliance framework. 
This compliance plan includes a robust review process, including 
Sarbanes-Oxley testing, self-auditing, and formal audits by internal 
and external audit.

    Question. Any past or ongoing issues of non-compliance.

    Answer. Since the implementation of AstraZeneca's compliance 
framework, we are not aware of any compliance issues that have been 
identified via this internal and external audit process.

    Question. Any corrective actions taken to address identified 
problems or issues of non-compliance with the MDRP and how such steps 
were communicated to the Centers for Medicare and Medicaid Services.

    Answer. As noted above, to date, no compliance issues have been 
identified via this internal and external audit process.

    Question. Any steps taken to improve compliance and ensure that all 
Medicaid drug rebates owed to the Federal Government and the States are 
paid in full.

    Answer. AstraZeneca has a comprehensive compliance framework that 
includes Sarbanes-Oxley testing, self-auditing, and formal audits by 
internal and external audit. Additionally, as it relates to Medicaid 
drug rebates owed to the Federal Government and States, AstraZeneca 
performs additional reviews of claims-level data, ensuring the 
completeness and accuracy of both the payments made by manufacturers as 
well as claims submitted to manufacturers. This process has identified 
duplicate pharmacy claims submitted to State Medicaid Agencies 
resulting in overpayment by both States and manufacturers. Clearly, 
these overpayments disadvantage both the States and manufacturers like 
AstraZeneca.
                 bonus payments tied to specific drugs
    Question. I am concerned by the potential for employee financial 
incentives to encourage high launch prices and price increases for 
prescription drugs.

    Is your salary, bonus, or other compensation tied to sales or 
revenue targets of a single product your company sells? Has it ever 
been? If yes, please state the product or products to which your 
salary, bonus or other compensation was tied.

    Answer. The CEO's compensation as well as the compensation of other 
senior leaders is directly based on three areas of performance that are 
generally weighted equally: development and delivery of innovative 
science, our aggregate sales, and other important financial metrics.

    AstraZeneca understands that executive pay is a closely scrutinized 
issue. As part of our compensation decisions, we are mindful of the 
sensitivity of this issue as we determine how best to incentivize, 
reward and retain executives capable of leading a global pharmaceutical 
company in a highly competitive market.

    Question. Is your salary, bonus, or other compensation tied to 
either revenue or net income of the company as a whole? Has it ever 
been? If yes, please explain what assumptions about price increases are 
used when the compensation committee sets revenue or net income goals. 
Does the compensation committee provide any guidance to executives in 
regards to the amount of revenue that the company will generate from 
price increases versus volume growth?

    Answer. The CEO's compensation as well as the compensation of other 
senior leaders is directly based on three areas of performance that are 
generally weighted equally: development and delivery of innovative 
science, our aggregate sales, and other important financial metrics. 
AstraZeneca's Remuneration Committee does not provide any guidance on 
price increases.
        provision of rebates in exchange for formulary placement
    Question. In today's system, drug makers receive a limited time 
window to sell their drug without competition. After that period has 
expired, low-cost generics should become available. However, drug 
makers often prevent access to these cheaper generic drugs in Medicare. 
Researchers have found that 72 percent of Medicare Part D plans charged 
lower cost-sharing for a brand name drug compared to its generic 
equivalent. This means seniors were charged less out of pocket for 
brand name drugs compared to generics that are on average four times 
cheaper than the brand-named drug. This happens because drug makers pay 
a rebate to the Part D plans in order to give the more expensive drug 
better treatment than a generic. As a result, Medicare spending 
increases due to the current structure of the Part D benefit.

    Has your company ever paid a rebate to a Part D plan so that a 
brand name drug would get preferential treatment (i.e., lower cost-
sharing or less utilization management) compared to a cheaper generic?

    Answer. In certain instances, AstraZeneca enters into arrangements 
under which a branded agent is discounted at or below the net cost of 
the generic(s) in the market, therefore benefiting the plan and the 
beneficiary. AstraZeneca typically enters into these types of 
arrangements for medicines already existing on formulary. These 
arrangements benefit patients by ensuring greater affordability for the 
branded medicine and by ensuring continuity of treatment if a patient 
has already been prescribed a branded medicine. These arrangements also 
support competition because they provide the opportunity for multiple 
competitors and medicine options to compete on price and other factors. 
We have had several such arrangements in Medicare Part D (see Appendix 
C).

    Question. If so, please provide:

    A list of the drugs for which your company has done this since 
January 1, 2014.

    Answer. A list providing this information is attached as Appendix 
C.

    Question. The number of Part D plans in which this type of rebate 
was given for each drug in each year.

    Answer. A list of the relevant Part D plans is included in Appendix 
C.
                               net prices
    Question. During your testimony, you stated, ``The estimates for 
2018 show that across our medicines, our average rebate is nearly 50 
percent of our gross revenues in the U.S. Despite this, in recent 
years, in our primary cap portfolio, we have seen flat to declining net 
effective prices for most of our medicines.''

    Please describe how the company's year-over-year aggregate net 
price is calculated.

    Answer. The analysis discussed during the hearing on February 26, 
2019 was completed by brand; the change in Net Price was calculated at 
the brand level, and then weighted based on Net Sales for each brand as 
a percent of Total Net Product Sales for 2018.\2\
---------------------------------------------------------------------------
    \2\ Net Product Sales reflect the invoiced amount less movements in 
estimated accruals for rebates and chargebacks given to managed-care 
and other customers. Cash discounts for prompt payment are also 
deducted from sales. Average Net Price per Unit excludes product 
returns, and the figures were arrived at using the conventional Net 
Price calculation, that is, before deducting cost of goods sold, 
royalties, and variable selling expenses.

---------------------------------------------------------------------------
    Question. Please also specifically address the following questions:

    How many products are included in the calculation of the average 
net price change? What was the median net price change?

    Answer. The analysis discussed during the hearing on February 26, 
2019 included 26 brands that represent 98 percent of annual Net Product 
Sales in the United States for the period ending December 31, 2018.

    The Median Price Change (prior to weighting) was a Net Price 
decrease of 1 percent.

    Question. Is net price weighted? If so, how? For example, in 
determining the aggregate net price does the company assign different 
weights to different products based on volume or other factors? Are 
``on patent'' and ``off patent'' drugs weighted identically? Are other 
statistical weights used or are all products treated equally?

    Answer. The analysis discussed during the hearing on February 26, 
2019 was completed by brand; the change in Net Price was calculated at 
the brand level, and then weighted based on Net Sales for each brand as 
a percent of Total Net Product Sales for 2018 irrespective of whether 
the medicines are on or off patent.

    Question. Does the figure that you provided during your testimony 
account for U.S. prices, international prices, or both? Generally 
speaking, when your company reports net price changes, does it 
differentiate between U.S. and international prices?

    Answer. The analysis discussed during the hearing on February 26, 
2019 referred to 26 brands that represent 98 percent of annual Net 
Product Sales in the United States for the period ending December 31, 
2018.

    Question. Please list the five drugs your company sold in the U.S. 
that had the greatest year-over-year net price increase in 2018, noting 
the increase for each drug by dollar figure and percentage. Please list 
the five drugs your company sold in the U.S. that had the lowest year-
over-year net price increase (and/or the greatest decrease) in 2018, 
noting the increase (or decrease) for each drug by dollar figure and 
percentage.

    Answer. In 2018, we experienced a Weighted Average Net price 
decline in our hyper-competitive respiratory and diabetes therapeutic 
areas, with declines of 2.4 percent and 1.9 percent, respectively. Our 
Weighted Average Net prices in oncology remained flat. Brand-specific 
pricing information is competitively sensitive information.

    Question. For 2018, what was the average net price change in the 
U.S. market for (1) drugs with no competition, (2) drugs with only 
branded competition, and (3) drugs with generic competition?

    Answer. For 2018, the Weighted Average Net price change in the 
United States market for:

          Medicines with no competition was an increase of 0.6 
        percent;

          Branded ``on patent'' medicines without generic equivalents 
        was a decrease of 4.7 percent;

          ``Off patent'' medicines with generic equivalent competition 
        was an increase of 4.6 percent.

    With respect to the last category of medicines described above, we 
note by way of context that once generic options enter the market, our 
market share rapidly erodes, as many PBMs, insurers, and government 
agencies to which AstraZeneca offers rebates and discounts replace our 
branded medicines on their formularies with these generic competitors. 
Accordingly, the mix of business for medicines with generic competition 
shifts towards programs whereby health plans/PBMs chose to list our 
branded medicines on their formularies given a lower net cost versus 
generics, and to individual patients who chose to pay for branded 
agents over generic agents, resulting in a higher average net effective 
price across all distribution channels.

    Question. You state that ``the estimates for 2018 show that across 
our medicines, our average rebate is nearly 50 percent of our gross 
revenues in the U.S.'' For each product, please disclose the gross 
revenue and the amount of rebates paid.

    Answer. The table below reflects our Product Sales in the U.S. for 
the period ending December 31, 2018, including the proportion of Gross 
Sales allocated to estimated amounts we expect to pay to third-party 
managed care organizations, hospitals, long-term care facilities, group 
purchasing organizations, and various Federal or State programs. The 
percentage of Gross Product Sales column reflects our effective rebate 
rate per channel, a combination of mix of business in that channel and 
related rebate rate.

------------------------------------------------------------------------
                                           USD (in         % of Gross
                                          millions)       Product Sales
------------------------------------------------------------------------
Gross Product Sales                        $16,538,000
------------------------------------------------------------------------
Chargebacks                               $(2,224,000)              -13%
------------------------------------------------------------------------
Regulatory--Medicaid and State            $(1,304,000)               -8%
 programs
------------------------------------------------------------------------
Contractual--Managed-care and             $(4,600,000)              -28%
 Medicare
------------------------------------------------------------------------
Cash and other discounts                    $(286,000)               -2%
------------------------------------------------------------------------
Customer returns                            $(119,000)               -1%
------------------------------------------------------------------------
U.S. Branded Pharmaceutical Fee             $(140,000)               -1%
------------------------------------------------------------------------
Other                                       $(989,000)               -6%
------------------------------------------------------------------------
Net Product Sales                           $6,876,000
------------------------------------------------------------------------
Brand-specific pricing information is competitively sensitive
  information.


                                 ______
                                 
              Questions Submitted by Hon. Robert Menendez
    Question. During the hearing, when I asked whether your company 
engaged in tactics to delay generic production of your products, you 
answered ``no.'' However, AstraZeneca appears on the FDA's list of 
companies who have access complaints against them.

    Can you explain the discrepancy between your answer and the FDA 
list? The FDA list can be found here: https://www.fda.gov/Drugs/
DevelopmentApprovalProcess/HowDrugsareDevelopedandApproved/
ApprovalApplications/AbbreviatedNewDrug
ApplicationANDAGenerics/ucm607738.htm.

    Answer. AstraZeneca appreciates the opportunity to address the 
question of one of our medicines (BRILINTA) appearing on the Reference 
Listed Drug Access Inquiries list (RLD List). We would first like to 
state that AstraZeneca supports allowing generic manufacturers access 
to samples. Withholding or otherwise blocking such access is 
inconsistent with that position. Our internal review has not identified 
any unanswered, delayed, or outstanding requests for samples of 
BRILINTA (ticagrelor) by any generic manufacturers.

    It is our understanding that BRILINTA was included on the RLD List 
based on a single inquiry received by the FDA. Unfortunately, the RLD 
List does not identify the company that reportedly requested 
information (or samples) from AstraZeneca, the date the information was 
requested, or any other information that would allow AstraZeneca to 
better understand or further investigate the circumstances of this 
inquiry. On its website, the FDA does advise that it has ``not 
independently investigated or confirmed the access limitations 
described in the inquiries received.'' Given this limitation, the 
listing of an inquiry on the RLD List does not mean that the FDA has in 
fact determined that access to samples by generic manufacturers was 
limited or withheld for the medicines identified. Indeed, based on our 
internal review, we have not identified any circumstances that 
substantiate the inquiry received by the FDA relating to BRILINTA.

    BRILINTA is and has always been available via normal commercial 
distribution channels (i.e., wholesalers) since its U.S. launch. It has 
never had a restricted distribution program.

    Finally, more than 15 generic manufacturers have applied for 
regulatory approval from the FDA for the manufacture of generic 
ticagrelor and some, like Watson/Teva, have received tentative 
approvals from the FDA. Because conducting bioequivalence studies with 
the branded medicine is an FDA preapproval requirement, it is clear 
that these generic manufacturers are not having difficulty accessing 
branded ticagrelor for their studies.

    In light of the context provided above, it is unclear why any 
generic manufacturer would be unable to obtain a sample of BRILINTA for 
their purposes or why an inquiry was lodged with the FDA related to 
this medicine.

    Question. When new products enter the market, do drug companies set 
high initial rebates and then provide deep rebates in order to gain 
access to insurance plan's formularies?

    Answer. No, this is not AstraZeneca's general practice. We 
negotiate rebates and discounts with payers and pharmacy benefit 
managers (PBMs)--including in Medicare Part D--to help ensure that 
patients have the most robust access possible to our therapies. Without 
these discounts and rebates, many lifesaving medicines would not be 
placed on plan formularies and therefore would be largely unavailable 
to the patients who need them most.

    The current rebate system creates misaligned incentives. This 
results in a growing differential between list and net prices. We 
support reforms of this system that include the elimination of rebates 
in the commercial sector and in Medicare Part D, which will result in 
the reduction of the differential between list and net prices and which 
would allow manufacturers to ensure that the initial list price of a 
drug reflects its net value.

    Question. If CMS finalizes the rebate rule, do you anticipate 
future products entering the market with significantly lower initial 
list prices?

    Answer. We believe that eliminating rebates across Medicare Part D 
and commercial will generally result in lower initial list prices than 
in the absence of reform, although the impact on specific medicines 
will vary based on the competitive dynamics for that medicine. Reform 
only in Part D and not commercial is unlikely to impact initial list 
price setting practices, as the current structure does not allow for 
two separate list prices (i.e., one list price for Part D and a 
different list price for the commercial sector).

                                 ______
                                 
              Questions Submitted by Hon. Thomas R. Carper
    Question. What are your recommendations for lowering prices for the 
40 percent of drugs that do not offer rebates in Medicare Part D? In 
the health insurance plans that you offer your employees, do you ask 
your insurers to pass through the full manufacturer rebates to the 
beneficiaries?

    Answer. All of our medicines are rebated under the statutory 
requirements of Medicaid, Federal Supply Schedule, 340B, and the Part D 
coverage gap discount program. For our highly innovative, targeted 
therapies, we do not typically provide additional rebates other than 
through our value-based agreements, where such discounts are based on 
patient outcomes.

    In general, medicines with minimal rebates are the newest and most 
innovative on the market. Expanded use of value-based agreements is a 
key component to lowering costs and improving access to these medicines 
that are currently not in highly rebated therapeutic classes. Under 
such arrangements, manufacturers may contract to reimburse plans if the 
medicine does not work as expected, lowering risks for the payer. This 
also results in competition across manufacturers of medicines in these 
classes by facilitating competition across clinical results and 
outcomes.

    As we stated before the Senate Committee on Finance, AstraZeneca 
has put forward several proposals in addition to value-based agreements 
to address drug pricing:

          Moving away from the current rebate system, while continuing 
        to work with payers and PBMs to ensure robust negotiations;

          Using a portion of discounts and rebates to create out-of-
        pocket caps for Medicare patients;

          Encouraging biosimilars and eliminating policy and 
        commercial barriers to their greater use.

    AstraZeneca also supports increased transparency across the 
biopharmaceutical supply chain, including transparency with respect to 
drug pricing. To that end, we generally support the policies included 
in the current versions of the SPIKE and C-THRU Acts. There are a 
variety of state-level drug pricing transparency laws and regulations. 
We believe that having a consistent, federal standard for drug pricing 
transparency requirements, like those included in the SPIKE Act, should 
pre-empt state level laws to reduce confusion and compliance burden.

    We also support transparency efforts to ensure that patients and 
prescribers have meaningful information on out-of-pocket costs at the 
point of prescribing, so that they can make informed decisions about 
the most appropriate and affordable therapy.

    AstraZeneca wants to be a constructive partner in identifying 
solutions that continue to allow manufacturers to innovate while 
creating a more efficient and more affordable system.

    AstraZeneca provides generous health-care benefits to its 
employees. Today, we provide a point-of-sale discount on prescription 
medicines in the form of low out-of-pocket costs for our employees. We 
cap our employees' out-of-pocket costs on prescription medicines at $50 
per fill to ensure they do not forgo their prescriptions due to high 
out-of-pocket costs.

    Question. The systems for pricing and distributing drugs are opaque 
and difficult to understand.

    What are your recommendations for increasing transparency in how 
your companies set the list prices for drugs, and for improving 
transparency in the supply chain for prescription drugs? Would you 
support Federal standards for transparency in setting the list prices 
for drugs?

    Answer. We do believe that greater transparency is needed for 
manufacturers as well as other entities in the supply chain. We 
therefore would generally support transparency requirements such as 
those included in the SPIKE and C-THRU Acts. Any transparency 
requirements should consider the need to protect competitively 
sensitive information to ensure robust competition in the market.

    There are a variety of State-level drug pricing transparency laws 
and regulations. We believe that having a consistent, Federal standard 
for drug pricing transparency requirements, like those included in the 
SPIKE Act, should pre-empt State-level laws to reduce confusion and 
compliance burden.

    Question. In nearly every sector of the health-care industry, 
Medicare, Medicaid, employers, and insurers are moving away from fee-
for-service payments to reimbursements based on value and performance. 
Prescription drugs and medical devices were the glaring exceptions to 
this trend until recently.

    How many of your drugs are included in value-based contracts and 
how many patients are benefiting from them? How do these value-based 
contracts work to lower drug prices for both patients and taxpayers?

    Answer. We believe medicines are part of the solution to 
controlling health-care costs. They not only improve patient outcomes 
and increase quality of life, but also reduce downstream costs. Value-
based agreements allow us to reimburse the health-care system if our 
medicines do not deliver as intended. This solution demonstrates our 
willingness to stand behind the value of our medicines.

    AstraZeneca is working closely with payers and health systems to 
explore innovative solutions to improve access and affordability that 
demonstrate the value our medicines bring to patients and the health-
care system. Our value-based agreements aim to manage the totality of 
treatment costs and keep people healthy and out of the hospital. For 
several years, AstraZeneca has been exploring these types of solutions 
through value-based agreements where we are willing to work with 
health-care stakeholders to tie payment to patient outcomes.

    To date, we have entered into approximately 40 value-based 
agreements for 15 medicines across our therapeutic areas with a variety 
of payers, making AstraZeneca a leader in the field of value-based 
agreements. Tens of thousands of patients have benefited from improved 
access as part of these agreements.

    As an example, and as noted in our written testimony submitted to 
the Senate Committee on Finance, AstraZeneca agreed with Express 
Scripts that for IRESSA, an oral treatment for certain types of lung 
cancer, we will fully reimburse Express Scripts for discontinued use 
before the third fill, including if discontinuation occurs because 
patients did not respond to treatment.

    While most of these agreements have been focused on securing 
patient access to our medicines and delivering better patient outcomes, 
where payers are willing, we are also looking to more directly address 
patient out-ofpocket affordability through these innovative 
arrangements.

    As an example, we recently announced the initiation of a value-
based agreement for University of Pittsburgh Medical Center (UPMC) 
Medicare patients who are prescribed BRILINTA. This value-based 
contract, which was effective as of January 1, 2019, is groundbreaking 
in two ways. First, the contract lowers the out-of-pocket costs for a 
UPMC Medicare Part D patient to approximately $10 for a 30-day supply. 
Second, what UPMC pays for BRILINTA will vary based on patient 
outcomes, tying the cost of the medicine to its real-world clinical 
performance.

    We are currently exploring another value-based agreement in 
Medicare Part D. In addition to having a significant outcomes-based 
component, this arrangement would reduce patient out-of-pocket costs. 
This type of agreement allows patients to access their medicines at a 
lower out-of-pocket cost and payers to control their overall health-
care costs through paying for outcomes.

    Question. Last year, Senator Portman and I did an investigation on 
the pricing of an opioid overdose reversal drug called EVZIO, 
manufactured by Kaleo. Kaleo increased the price of EVZIO from $575 in 
2014 to $4,100 in 2017. We found that the best price Medicare was able 
to get for EVZIO, about $4,000, was much higher than the price other 
federal programs and private insurers were able to get. It seemed that 
Kaleo was able to get this higher price of $4,000 from Medicare by 
helping doctors fill out paperwork showing that the drug was medically 
necessary, even though there are cheaper alternatives on the market. As 
a result of the investigation, Kaleo announced it will bring a generic 
version of the drug to market at only $168 per pack.

    Are any of your companies providing medical necessity paperwork to 
doctors in order to get your drugs covered by Medicare?

    Answer. AstraZeneca policies prohibit completing medical necessity 
paperwork for doctors or their staff as described in your inquiry.

    Question. In 2017, the Rand Corporation estimated that biosimilar 
drugs, which are competitors to complex, biologic drugs, could save the 
United States more than $50 billion over the next decade. Some of you 
have also argued that increasing the use of biosimilar drugs would help 
lower drugs costs for consumers and taxpayers.

    What is delaying the uptake of biosimilar drugs in the United 
States? What policies do you recommend to increase the development of 
biosimilar drugs?

    Answer. AstraZeneca believes that competition is a key component to 
reducing costs, and that is why we support the expanded use of 
biosimilars in the U.S. As a global company, we operate in countries, 
particularly those in the European Union, where biosimilar competition 
is particularly robust. We support a similarly vigorous biosimilars 
market in the U.S.

    There are several challenges to biosimilar uptake in the U.S., 
including contracting and rebating dynamics and difficulty in obtaining 
interchangeability status. We therefore appreciate the efforts of the 
FDA to increase the availability of biosimilars in the U.S., including 
the FDA's development of a Biosimilars Action Plan. We support efforts 
to streamline and improve the efficiency of the biosimilars approval 
pathway for the benefit of patients. Such efforts could include 
increased transparency into the patents applicable to biologic 
medicines.

    We also support reimbursement policies that facilitate the uptake 
of biosimilars. Such policies include Medicare reimbursement rates that 
ensure that biosimilars can compete on equal footing with innovator 
medicines, and reductions to cost-sharing amounts for biosimilars. We 
also believe the elimination of rebates will help biosimilars compete 
with innovator medicines.

                                 ______
                                 
             Questions Submitted by Hon. Benjamin L. Cardin
    Question. The United States is one of the only countries in the 
world to allow prescription drug manufacturers to advertise directly to 
consumers through magazines, billboards, radio, and television 
commercials. While I will not argue that it is beneficial to educate 
consumers about an unfamiliar disease and encourage them to seek 
medical help, most commercials from all of your companies recommend 
asking about a specific brand name drug, not a medical condition. 
Furthermore, even if your advertisements follow all FDA rules and list 
medication side effects, they also almost always list these while a 
smiling, apparently healthy person is walking on a beach. Researchers 
say that this type of imagery, combined with viewing hours of drug 
commercials each month, leads consumers to underestimate the risks 
associated with medications. For the past decade, studies have shown 
that aggressive direct-to-consumer advertising is associated with 
rising drug prices and an increase in inappropriate drug prescriptions.

    Since researchers have concluded that consumers are 
misunderstanding the benefits and risks described in your ads, what 
further policies could help you and your colleagues ensure that you are 
educating patients in a clear manner?

    Answer. Our advertising complies with regulatory requirements 
governing direct-toconsumer (DTC) advertising and AstraZeneca believes 
that DTC advertising is important to raising brand and disease 
awareness, fostering patient education, and enhancing the dialogue 
between patients and their physicians. Unfortunately, these positive 
impacts of health-care communication efforts are often left out of the 
DTC debate.
           pharmaceutical companies continue to raise prices
    Question. As you are well aware, high prescription drug prices are 
the number one concern for Americans and their families. According to 
the Organization for Economic Cooperation and Development, the average 
American spends around $1,208 annually on prescription drugs. There 
have been several instances where brand name or even generic drugs that 
have been on the market for years continue to increase in price. One of 
the most well-known examples is Mylan's increase of the price of EpiPen 
from less than $100 in 2007 to more than $600 in 2016. Another example, 
is the ever-increasing price of insulin. Sanofi increased the price of 
a vial of Lantus from $88.20 in 2007 to $307.20 in 2017. And those are 
just a small sample of price increases.

    Why don't we see price decreases for drugs that have been on the 
market for years without new formulations or added benefit?

    Answer. As an initial matter, it is important to note the 
distinction between list and net prices. Over the past several years, 
discounts and rebates for our therapies have increased overall, both in 
the commercial sector and Part D. In recent years, in our primary care 
portfolio, which includes the majority of our therapies, we have seen 
flat to declining net effective prices to AstraZeneca for most of our 
medicines. Flat to declining net prices is a trend across the industry.

    However, the current system makes list price decreases challenging.

    Therefore, to accomplish meaningful change in terms of lowering 
list price, the system must be restructured to eliminate rebates. 
Assuming the HHS rebate rule is finalized largely as proposed, 
AstraZeneca intends to comply with its requirements and use point-of-
sale discounts. Our goal is to maintain net prices broadly in line with 
today, recognizing our ability to do so may be dependent on external 
factors and market response such as how plans evolve their benefit 
design and the total degree of transparency under the new model.

    AstraZeneca would plan to reduce list prices, pending reforms 
across all payers, including in the commercial sector in addition to 
Part D, as the current construct does not allow for two separate list 
prices (i.e., one list price for Part D and a different list price for 
the commercial sector). Therefore, we also support efforts to eliminate 
rebates in the commercial sector, and recommend that Congress explore 
such legislation. While eliminating rebates is an important step, 
benefit designs must also be evaluated.
                             pay for delay
    Question. Pay for delay is a tactic that more and more branded drug 
manufacturers have been using to stifle competition from lower-cost 
generic manufacturers. This allows you to sidestep competition by 
offering patent settlements that pay generic companies not to bring 
lower-cost alternatives to market. These ``pay-for-delay'' patent 
settlements benefit both brand-name pharmaceutical companies by helping 
them avoid costly patent litigation and general manufacturers by 
rewarding them a hefty sum to delay entering the market with a cheaper 
drug alternative. However, these deals do not benefit consumers. 
According to an FTC study, these anticompetitive deals cost consumers 
and taxpayers $3.5 billion in higher drug costs every year.

    Does your company partake in pay-for-delay settlements?

    Answer. AstraZeneca does not enter into settlements that pay 
generic competitors to delay entry into the market. In the absence of a 
settlement, a generic would not necessarily prevail in the patent 
litigation and therefore would not be able to enter the market. Indeed, 
AstraZeneca has entered into many early-entry patent settlements that 
permit generic competitors to enter the market before expiration of 
AstraZeneca's patent rights by allowing generic manufacturers to 
license innovator patents.

    All of AstraZeneca's patent settlements fully comply with the law. 
These settlements provide increased clarity and stability to both 
parties, allowing innovators like AstraZeneca to continue investing 
substantially in new medicines for patients and frequently allowing 
generic competitors to enter the market before expiration of 
AstraZeneca's patent rights.

    Question. Why would a pharmaceutical company enter into a pay-for-
delay agreement?

    Answer. AstraZeneca does not enter into agreements that pay generic 
competitors to delay entry into the market.

    Question. Do you think these agreements stifle competition and 
prevent generic alternatives to your branded medications?

    Answer. AstraZeneca does not enter into agreements that pay generic 
competitors to delay entry into the market. However, AstraZeneca has 
entered into many early-entry patent settlements that permit generic 
competitors to enter the market before expiration of AstraZeneca's 
patent rights by allowing generic manufacturers to license innovator 
patents. These do not stifle competition but instead permit early entry 
by resolving patent disputes that would otherwise prevent generic 
alternatives to branded medication.
                          value-based pricing
    Question. One idea I wanted to get your thoughts on today, is the 
idea of value-based pricing. This is an idea where a company could link 
the single price it charges for a given drug to an assessment of how 
well it works. Some value-based pricing arrangements could allow 
insurers and patients to receive rebates from drug manufacturers if a 
drug failed to work (outcome-based pricing). Another version would 
involve ``indication-based pricing'' in which drug companies charge 
different prices for the same drug when it is used to treat different 
conditions.

    Dr. Soriot, we have heard that AstraZeneca has been participating 
in a value-based program in collaboration with the University of 
Pittsburgh Medical Center.

    Could you talk more about your research in value-based pricing and 
how you believe this could be possible solution to some of the high 
drug prices?

    Answer. We believe medicines are part of the solution to 
controlling health-care costs. They not only improve patient outcomes 
and increase quality of life, but also reduce downstream costs. Value-
based agreements allow us to reimburse the health-care system if our 
medicines do not deliver as intended. This solution demonstrates our 
willingness to stand behind the value of our medicines.

    AstraZeneca is working closely with payers and health systems to 
explore innovative solutions to improve access and affordability that 
demonstrate the value our medicines bring to patients and the health-
care system. Our value-based agreements aim to manage the totality of 
treatment costs and keep people healthy and out of the hospital. For 
several years, AstraZeneca has been exploring these types of solutions 
through value-based agreements where we are willing to work with 
health-care stakeholders to tie payment to patient outcomes.

    To date, we have entered into approximately 40 value-based 
agreements across our therapeutic areas with a variety of payers.

    Our research in value-based agreements has been focused on 
addressing the comprehensive value of a medicine in terms of medical 
cost offsets and the economic impact of achieving certain health 
benefits with a medicine in a specific population. Our experience in 
this area consists of health economics and outcomes research (HEOR) and 
real-world evidence (RWE) studies which correlate improved outcomes and 
overall better health to a direct, positive economic impact, realized 
by both the payer and the patient. We use HEOR and RWE data to 
establish the metrics of the value-based agreement. Another important 
part of our value-based agreement research is how we measure the impact 
of a value-based agreement, so we can learn what works and what does 
not work for future iterations of value-based agreements.

    In addition, by aligning payments for medicines more directly with 
their value in improving health outcomes and/or reducing the need for 
other healthcare services (such as hospitalizations), value-based 
arrangements make pharmaceutical manufacturers accountable for the 
results our medicines achieve and can help improve patients' health and 
maximize the benefits of healthcare spending. Over time, proliferation 
of value-based agreements can shift utilization toward medicines with 
greater clinical value and greater ability to reduce hospitalizations 
and other costly services, resulting in better health outcomes and 
lower overall healthcare spending.

    As manufacturers develop more complex, personalized, and promising 
treatments--such as gene therapies, cell therapies, or immuno-
therapies--it will be increasingly important for health plans to enter 
into value-based agreements so that they and our healthcare system may 
recognize the full value of those treatments and make them available to 
patients at affordable out-of-pocket amounts. Value-based agreements 
serve an important role in linking the price of a medicine to 
beneficiaries' demonstrated real world outcomes using that medicine.

    While most of these agreements have been focused on securing 
patient access to our medicines, some have also helped payers identify 
which patient types are most likely to benefit from our medicines and 
deliver improved patient outcomes. Partnering to drive this type of 
clarity can reduce overall drug spend in meaningful ways. Where payers 
are willing, we are also looking to more directly address patient out-
of-pocket affordability through these innovative arrangements.

    As you mention, we recently announced the initiation of a value-
based agreement for University of Pittsburgh Medical Center (UPMC) 
Medicare patients who are prescribed BRILINTA. This value-based 
contract, which was effective as of January 1, 2019, is groundbreaking 
in two ways. First, the contract lowers the out-of-pocket costs for a 
UPMC Medicare Part D patient to approximately $10 for a 30-day supply. 
Second, what UPMC pays for BRILINTA will vary based on patient 
outcomes, tying the cost of the medicine to its real-world clinical 
performance.

    Through the partnership of payers and policymakers, we look forward 
to a future where implementation of value-based agreements across 
public and private payers is widespread. Value-based agreements are one 
proactive solution; they are not the only solution.
                            drug rebate rule
    Question. In January, the Department of Health and Human Services' 
(HHS) Office of Inspector General (OIG) promulgated a new regulation to 
remove regulatory safe harbor protections under the Anti-Kickback 
Statute (AKS) for rebates on prescription drugs rebates paid by 
manufactures to PBMs under Medicare Part D and for Medicaid managed 
care organizations (MCOs). The OIG proposal attempts to ban most 
rebates by eliminating their regulatory protections. The rule is 
predicted to increase net drug costs in its early years. The CMS 
actuaries estimate it would cost $196 billion over 10 years. Despite 
this high price tag, the beneficiary benefits are limited. The proposed 
rule notes that under the CMS Actuary's analysis, the majority of 
beneficiaries would see an increase in their total out-of-pocket 
payments and premium costs; reductions in total cost sharing will 
exceed total premium increases.

    I wanted to ask a question about the administration's rebate rule, 
which I understand that many of the drug manufacturers, and your main 
trade association, strongly support. According to an analysis of the 
rule by the Office of Actuaries at CMS, drug manufacturers are likely 
to initially retain 15 percent of the current rebates as higher net 
drug prices.

    Given that estimate, can you provide the committee with any 
assurances that prices will not increase under this proposed rule?

    Answer. Assuming the HHS rebate rule is finalized largely as 
proposed, AstraZeneca intends to comply with its requirements and use 
point-of-sale discounts. Our goal is to maintain net prices broadly in 
line with today, recognizing our ability to do so may be dependent on 
external factors and market response such as how plans evolve their 
benefit design and the total degree of transparency under the new 
model.

    AstraZeneca would plan to reduce list prices, pending reforms 
across all payers, including in the commercial sector in addition to 
Part D, as the current construct does not allow for two separate list 
prices (i.e., one list price for Part D and a different list price for 
the commercial sector). Therefore, we also support efforts to eliminate 
rebates in the commercial sector, and recommend that Congress explore 
such legislation. While eliminating rebates is an important step, 
benefit designs must also be evaluated.

                                 ______
                                 
               Questions Submitted by Hon. Sherrod Brown
    Question. According to an article recently published in the Journal 
of the American Medical Association, medical marketers spent nearly $30 
billion dollars in 2016, up from $17 billion in 1997. Direct-to-
Consumer (DTC) advertising had the biggest percentage increase: from 
$2.1 billion, or 11.9 percent of all medical marketing, in 1997 to $9.6 
billion, or 32 percent of total spending, in 2016.

    Can you please provide what your ratio of spending on sales and 
marketing to research and development is today?

    Answer. In 2018, we spent $5.9 billion on RandD and $6.1 billion on 
Sales and Marketing, globally. Our Sales and Marketing figures include 
all costs incurred in selling, marketing, promoting, and distributing 
our products.
                             price-gouging
    Question. Sanofi, as I understand it, has made a pledge to the 
public to limit its price increases to the national health expenditures 
growth projection.

    Would your company commit to a cap on annual price increases as 
part of your PhRMA membership criteria?

    Answer. Our decisions around pricing would always need to remain 
independent of PhRMA membership criteria.

    Question. What policies would you propose to help ensure lower 
launch prices for new drugs?

    Answer. As we stated at the Senate Committee on Finance hearing, 
AstraZeneca has put forward a number of proposals to address drug 
pricing, including:

          Moving away from the current rebate system, while continuing 
        to work with payers and PBMs to ensure robust negotiations; and

          Encouraging biosimilars and eliminating policy and 
        commercial barriers to their greater use.

           As described below, we also support efforts to increase 
        transparency in the biopharmaceutical supply chain and drug 
        pricing specifically.
                              transparency
    Question. In many of your testimonies, you mentioned that the 
current system of pharmacy benefit manager (PBM) back-end rebates do 
not rarely results in a scenario where the PBM passes on savings to 
consumers at the point of sale (POS). The administration recently 
proposed a rule to eliminate the anti-kickback statute safe harbor 
protections for these drug rebates.

    Do you agree that greater transparency should be required to 
understand how manufacturers and PBMs are negotiating prices and 
rebates to ensure that savings are passed down to beneficiaries?

    Answer. Yes, AstraZeneca agrees that greater transparency is 
needed. We therefore generally support the policies included in the 
current versions of the SPIKE and C-THRU Acts.

    There are a variety of State-level drug pricing transparency laws 
and regulations. We believe that having a consistent, federal standard 
for drug pricing transparency requirements, like those included in the 
SPIKE Act, should pre-empt state level laws to reduce confusion and 
compliance burden.
                                  pbms
    Question. An Axios article from March 7, 2019 highlights the fact 
that, while ``pharmaceutical companies put a lot of the blame for high 
drug prices on pharmacy benefit managers,'' many large pharmaceutical 
companies ``rely on PBMs to manage their own health-care benefits.''

    In your role as an employer, does your company contract with a 
pharmaceutical benefit manager (PBM) to administer the prescription 
drug benefits for your employees and negotiate lower drug costs on your 
behalf?

    Answer. AstraZeneca prescription drug benefits are managed by 
Express Scripts.

    Question. For those of you who do use a PBM to help manage the 
prescription drug benefit for your employees, how do you utilize the 
rebates your PBM negotiates to lower health-care costs or drug costs 
for your employee plans and what does your company do with that 
savings? Specifically, do the savings go toward lowing premiums?

    Answer. AstraZeneca provides generous healthcare benefits to its 
employees. Today, we provide a point-of-sale discount on prescription 
medicines in the form of low out-of-pocket costs for our employees. We 
cap our employees' out-of-pocket costs on prescription medicines at $50 
per fill to ensure they do not forgo their prescriptions due to high 
out-ofpocket costs.

    Question. For those of you who do use a PBM to help manage the 
prescription drug benefit for your employees, does your PBM offer 
point-of-sale rebates to your employees?

    Answer. While AstraZeneca does not currently offer point-of-sale 
rebates to employees, we are exploring opportunities to evolve our 
benefits in the future.

                                 ______
                                 
             Questions Submitted by Hon. Sheldon Whitehouse
    Question. Please describe any policy changes you support that would 
result in your company lowering the list prices of its drugs.

    Answer. The current rebate construct is the key challenge in 
reducing list prices and we would support legislation that would 
eliminate rebates in Part D and the commercial sector. Assuming the HHS 
rebate rule is finalized largely as proposed, AstraZeneca intends to 
comply with its requirements and use point-of-sale discounts. Our goal 
is to maintain net prices broadly in line with today, recognizing our 
ability to do so may be dependent on external factors and market 
response such as how plans evolve their benefit design and the total 
degree of transparency under the new model.

    AstraZeneca would plan to reduce list prices, pending reforms 
across all payers, including in the commercial sector in addition to 
Part D, as the current construct does not allow for two separate list 
prices (i.e., one list price for Part D and a different list price for 
the commercial sector). Therefore, we also support efforts to eliminate 
rebates in the commercial sector, and recommend that Congress explore 
such legislation. While eliminating rebates is an important step, 
benefit designs must also be evaluated.

    Question. How much does your company's research and development 
portfolio rely on taxpayer-funded research conducted by the National 
Institutes of Health (NIH)? How many of your company's products are 
based, at least in part, on NIH research, and how many are the result 
of research funded solely by your company?

    Answer. We collaborate with the National Institutes of Health and 
the National Cancer Institute, and these partnerships can lead to 
important advances for patients. However, biopharmaceutical companies 
conduct the vast majority of R&D needed to bring new medicines to 
patients and they bear the associated costs and risks.

    Question. In each of the last 5 years, how much has your company 
spent on research and development versus the advertising and marketing 
of your products?

    Answer. Last year alone, we invested nearly $6 billion in R&D, 
which represents 28 percent of our total product sales, well above the 
industry average.

    Our Sales and Marketing figures include all costs incurred in 
selling, marketing, promoting, and distributing our products.

------------------------------------------------------------------------
              Year                 R&D Investment   Sales and Marketing
------------------------------------------------------------------------
2018                                  $5.9 billion          $6.1 billion
------------------------------------------------------------------------
2017                                  $5.8 billion          $5.6 billion
------------------------------------------------------------------------
2016                                  $5.9 billion          $5.8 billion
------------------------------------------------------------------------
2015                                  $6.0 billion          $6.6 billion
------------------------------------------------------------------------
2014                                  $5.6 billion          $7.1 billion
------------------------------------------------------------------------

    Question. During the hearing, you mentioned that your company would 
be likely to lower the list prices of its drugs if the recent proposal 
by the Trump administration to change the current system of rebates was 
extended to the private market.

    If the policy was extended to the private market, how large would 
the list price reductions be relative to the size of the rebates your 
company is currently providing?

    Answer. Assuming the HHS rebate rule is finalized largely as 
proposed, AstraZeneca intends to comply with its requirements and use 
pointof-sale discounts. Our goal is to maintain net prices broadly in 
line with today, recognizing our ability to do so may be dependent on 
external factors and market response such as how plans evolve their 
benefit design and the total degree of transparency under the new 
model.

    AstraZeneca would plan to reduce list prices, pending reforms 
across all payers, including in the commercial sector in addition to 
Part D, as the current construct does not allow for two separate list 
prices (i.e., one list price for Part D and a different list price for 
the commercial sector). Therefore, we also support efforts to eliminate 
rebates in the commercial sector, and recommend that Congress explore 
such legislation. While eliminating rebates is an important step, 
benefit designs must also be evaluated.

    Question. How will this proposal affect how your company sets the 
list prices for new drug products?

    Answer. We believe that eliminating rebates across Medicare Part D 
and commercial will generally result in lower initial list prices than 
in the absence of reform, although the impact on specific medicines 
will vary based on the competitive dynamics for that medicine. Reform 
only in Part D and not commercial is unlikely to impact initial list 
price setting practices, as the current structure does not allow for 
two separate list prices (i.e., one list price for Part D and a 
different list price for the commercial sector).

    Question. If the proposal is finalized and not extended to the 
private market, will your company make any list price reductions? If 
so, how large would the reductions be relative to the size of the 
rebates your company is currently providing?

    Answer. AstraZeneca would plan to reduce list prices, pending 
reforms across all payers, including in the commercial sector in 
addition to Part D, as the current construct does not allow for two 
separate list prices (i.e., one list price for Part D and a different 
list price for the commercial sector). Therefore, we also support 
efforts to eliminate rebates in the commercial sector, and recommend 
that Congress explore such legislation. While eliminating rebates is an 
important step, benefit designs must also be evaluated.

                                 ______
                                 
                Question Submitted by Hon. Maggie Hassan
    Question. In June of 2018, the Medicaid and CHIP Payment and Access 
Commission (MACPAC) unanimously recommended under Recommendation 1.1 in 
their annual report to Congress that Congress remove the statutory 
requirement that manufacturers blend the average manufacturer price 
(AMP) of a brand drug and its authorized generic.\3\ This requirement 
created an unintended loophole. Rather than use the price of the 
authorized generic, drug companies can sell its authorized generic to a 
corporate subsidiary at an artificially lower price, and use that lower 
price to bring down the AMP, which in turn lowers the rebate 
obligation.
---------------------------------------------------------------------------
    \3\ MACPAC, ``Improving Operations of the Medicaid Drug Rebate 
Program,'' https://www.macpac.gov/wp-content/uploads/2018/06/Improving-
Operations-of-the-Medicaid-Drug-Rebate-Program.pdf.

    Does your company engage in this practice? Has your company ever 
---------------------------------------------------------------------------
engaged in this practice in the past?

    Answer. No. In limited circumstances, AstraZeneca has made 
authorized generics available, but does so through a third-party 
distributor, not an AstraZeneca subsidiary.

                                 ______
                                 
           Questions Submitted by Hon. Catherine Cortez Masto
    Question. As a portion of your revenue, for what percentage of the 
drugs in your portfolio do you offer no rebates? Based on the drugs in 
your pipeline, do you foresee that portion growing? For those drugs, is 
your list price equal to your net price?

    Answer. All of our medicines are rebated under the statutory 
requirements of Medicaid, Federal Supply Schedule, 340B, and the Part D 
coverage gap discount program. For our highly innovative, targeted 
therapies, we do not typically provide additional rebates other than 
through our value-based agreements, where such discounts are based on 
patient outcomes. Therefore, due to statutory rebates and other fees 
and discounts, the net price is lower than list price for all 
medicines.

    Question. Do you invest more in R&D than you generate in U.S. sales 
revenue? Please include specific figures.

    Answer. In 2018, AstraZeneca's U.S. revenue was $6.88 billion. We 
invested $5.9 billion in R&D, globally.

    Question. Do you invest more in R&D than you spend on marketing and 
administration? What company functions do you consider to be included 
in administration? Please include specific figures.

    Answer. In 2018, we spent $5.9 billion on R&D and $10 billion on 
Selling, General and Administrative (SG&A) costs globally, which is 
inclusive of Sales and Marketing costs of $6.1 billion.

    Selling, General and Administrative expenses are defined as fixed 
costs of selling products and services and costs of central services 
and administration, which are not included in inventory values.

    General and administrative costs include costs of central services 
and administration, such as: Human Resources, Finance, Facilities, 
Purchasing, Strategy and Business Development, Legal, Corporate 
Affairs, and other corporate expenses.

    Our Sales and Marketing figures include all costs incurred in 
selling, marketing, promoting, and distributing our products.

    Question. Do you invest more in R&D than you spend on marketing and 
sales? What company functions do you consider to be included in sales? 
Please include specific figures.

    Answer. In 2018, we spent $5.9 billion on R&D and $6.1 billion on 
Sales and Marketing, globally.

    Our Sales and Marketing figures include all costs incurred in 
selling, marketing, promoting, and distributing our products.

    Question. Why do you advertise for the drugs you manufacture? What 
factors do you consider in choosing which drugs you advertise?

    Answer. We consider many factors when making decisions regarding 
the advertising of our medicines, including the opportunity to raise 
brand and disease awareness, patient education, and the enhancement of 
the patient/physician dialogue.

    We believe that health-care communications efforts can have a 
positive impact on patient health. AstraZeneca made a decision several 
years ago to use our direct-to-consumer (DTC) advertisements to share 
another important message with patients: We were the first company to 
include messages about our affordability programs in all of our DTC TV 
advertisements, making clear to patients that if they cannot afford 
their medicines, AstraZeneca may be able to help. We continue this 
practice today, which we believe is reflective of AstraZeneca's 
commitment to patient access and affordability.

                                 ______
                                 

                               Appendix A
------------------------------------------------------------------------
      Organization          Program Title        Date         Amount
------------------------------------------------------------------------
CARDIOVASCULAR RESEARCH  Chronic Total        01/07/2014       $5,000.00
 FOUNDATION               Occlusion and
                          Left Main Summit
                          2014: A Live
                          Demonstration
                          Course
------------------------------------------------------------------------
TORRANCE MEMORIAL        Cardiology Update    01/08/2014       $2,500.00
 MEDICAL CENTER           2014:
                          Conventional
                          Wisdom and Beyond
------------------------------------------------------------------------
SCRIPPS HEALTH           Grand Rounds in      01/09/2014       $8,027.93
                          Cardiovascular
                          Diseases
------------------------------------------------------------------------
UNIVERSITY OF CHICAGO    Sixth Annual         01/12/2014       $3,000.00
                          Morton Arnsdorf
                          Cardiovascular
                          Research Day at
                          the University of
                          Chicago
------------------------------------------------------------------------
FLORIDA OSTEOPATHIC      15th Annual          01/15/2014       $5,000.00
 MEDICAL ASSOCIATION      Cardiovascular
 DISTRICT SOCIETY 2       and Medicine
                          Symposium
------------------------------------------------------------------------
AMERICAN COLLEGE OF      25th Annual          01/16/2014       $5,000.00
 CARDIOLOGY--PUERTO       Meeting ACC
 RICO CHAPTER             Puerto Rico
                          Chapter
------------------------------------------------------------------------
NATIONAL ASSOCIATION OF  Improving Patient    01/23/2014      $25,000.00
 MANAGED CARE             Outcomes: Updated
 PHYSICIANS               Treatment
                          Strategies in the
                          Management of
                          Acute Coronary
                          Syndrome (ACS)
------------------------------------------------------------------------
UNIVERSITY MEDICAL       6th Annual           01/23/2014       $5,000.00
 CENTER OF SOUTHERN       Cardiovascular
 NEVADA                   and Stroke
                          Symposium
------------------------------------------------------------------------
SAINT JOSEPH'S           Antithrombotic       01/23/2014       $2,737.62
 HOSPITAL--ATLANTA        Protocol for
                          Acute Coronary
                          Sndrome
------------------------------------------------------------------------
GORDON RESERACH          Gordon Research      01/26/2014       $1,700.00
 CONFRENCE                Seminar--``Lipopr
                          otein
                          Metabolism''
------------------------------------------------------------------------
CLEVELAND CLINIC         Rheumatology Best    01/26/2014       $9,795.58
 EDUCATIONAL FOUNDATION   Practices 6th
                          Annual
                          Rheumatology
                          Highlights
                          Report--``Transla
                          ting an
                          International
                          Meeting into
                          Clinical
                          Practice''
------------------------------------------------------------------------
KERN ASPEN LIPID         Evolving Concepts    01/26/2014       $7,000.00
 CONFERENCE               of HDL Function
                          in
                          Cardiometabolic
                          Diseases and
                          Beyond
------------------------------------------------------------------------
ST. JOSEPH'S REGIONAL    Acute Coronary       01/27/2014       $2,225.00
 MEDICAL CENTER           Syndrome:
                          Evidence-Based
                          Management in the
                          Present Era
------------------------------------------------------------------------
NATIONAL LIPID           Lipid Academy        01/28/2014      $20,000.00
 ASSOCIATION              Series of 2
------------------------------------------------------------------------
NATIONAL LIPID           Masters in           01/28/2014      $20,000.00
 ASSOCIATION              Lipidology Series
                          of 2
------------------------------------------------------------------------
REGENTS OF THE           Rheumatology Grand   01/29/2014       $5,000.00
 UNIVERSITY OF            Rounds
 CALIFORNIA
------------------------------------------------------------------------
DUKE UNIVERSITY          Overview of the      01/29/2014       $5,439.84
                          Duke Health
                          Systems Acute
                          Coronary
                          Syndromes
                          suggested
                          algorithm of care
------------------------------------------------------------------------
PENNSYLVANIA ACADEMY OF  PAFP/F Smoking       01/29/2014      $13,666.00
 FAMILY PHYSICIANS        Cessation and
 FOUNDATION               Asthma Outcomes
                          CME
------------------------------------------------------------------------
JOHNS HOPKINS            Advances in the      01/30/2014      $30,000.00
 UNIVERSITY               Diagnosis and
                          Treatment of the
                          Rheumatic
                          Diseases
------------------------------------------------------------------------
EMORY UNIVERSITY         Emory Symposium on   01/30/2014       $5,000.00
                          Coronary
                          Atherosclerosis
                          Prevention and
                          Education
                          (ESCAPE)
------------------------------------------------------------------------
NURSE PRACTITIONER       Clinical Pearls      01/30/2014       $5,000.00
 ASSOCIATES FOR           for COPD
 CONTINUING EDUCATION
------------------------------------------------------------------------
NATIONAL ASSOCIATION OF  Practical            01/30/2014      $25,000.00
 MANAGED CARE             Strategies to
 PHYSICIANS               Improve Patient
                          Outcomes in the
                          Prevention and
                          Treatment of COPD
------------------------------------------------------------------------
ST. JOSEPH'S REGIONAL    COPD                 02/04/2014       $2,200.00
 MEDICAL CENTER
------------------------------------------------------------------------
AMERICAN ASSOCIATION OF  AACE 23rd Annual     02/04/2014      $16,130.00
 CLINICAL                 Scientific and
 ENDOCRINOLOGISTS         Clinical Congress
------------------------------------------------------------------------
NURSE PRACTITIONER       Cardiovascular       02/04/2014       $5,000.00
 ASSOCIATES FOR           Pharmacology:
 CONTINUING EDUCATION     Latest Updates in
                          Caring for the
                          Cardiac Patient
------------------------------------------------------------------------
MIDWEST CARDIOVASCULAR   Cardiology at the    02/04/2014       $5,000.00
 RESEARCH FOUNDATION      Bix
------------------------------------------------------------------------
AMERICAN COLLEGE OF      ACCs 63rd Annual     02/05/2014     $100,000.00
 CARDIOLOGY FOUNDATION    Scientific
                          Session (ACC.14)
                          Prevention
                          Learning Pathway
                          and Prevention
                          Pilot Program
------------------------------------------------------------------------
LA BIOMED                Cardiology Grand     02/05/2014       $5,000.00
                          Rounds: Updates
                          in ACS
------------------------------------------------------------------------
NEBRASKA ACADEMY OF      Ten Things You       02/05/2014       $5,500.00
 PHYSICIAN ASSISTANTS     Didn't Learn
                          About COPD in
                          Class (Even If
                          You Were Paying
                          Attention
------------------------------------------------------------------------
MINNESOTA SOCIETY OF     MSHP Annual          02/05/2014       $2,533.00
 HEALTH-SYSTEM            Meeting 2014:
 PHARMACISTS              Evidenced-based
                          Updates in the
                          Management of
                          Dyslipidemia
------------------------------------------------------------------------
CARDIOVASCULAR RESEARCH  20th Annual          02/05/2014      $15,000.00
 FOUNDATION               Interventional
                          Cardiology
                          Fellows Course
------------------------------------------------------------------------
AMERICAN COLLEGE OF      Best of ACC.14:      02/05/2014      $50,000.00
 CARDIOLOGY FOUNDATION    Take Home
                          Messages for the
                          Clinicians
------------------------------------------------------------------------
ENDOCRINE SOCIETY        ENDO 2014            02/06/2014      $40,000.00
                          Educational
                          Sessions
------------------------------------------------------------------------
ALL NYC EMERGENCY        All NYC Emergency    02/06/2014       $5,000.00
 MEDICINE CONFERENCE,     Medicine
 INC.                     Conference; In
                          the Footsteps of
                          Giants
------------------------------------------------------------------------
AMERICAN COLLEGE OF      Annual Scientific    02/09/2014      $10,000.00
 PHYSICIANS; PUERTO       Meeting
 RICO CHAPTER
------------------------------------------------------------------------
CARDIOVASCULAR RESEARCH  Optimizing PCI       02/09/2014       $5,000.00
 FOUNDATION               Outcomes: A
                          Vision for 2014
------------------------------------------------------------------------
INTERNATIONAL            14th Annual          02/10/2014      $12,500.00
 ASSOCIATION FOR THE      Targeted
 STUDY OF LUNG CANCER     Threapies of Lung
                          Cancer Meeting
------------------------------------------------------------------------
TENNESSEE ACADEMY OF     Breast and Ovarian   02/10/2014       $6,000.00
 PHYSICIAN ASSISTANTS     Cancer
------------------------------------------------------------------------
PURDUE UNIVERSITY        A 2014 National      02/12/2014      $30,000.00
                          Educational
                          Initiative on
                          Therapeutics and
                          Rheumatology for
                          Rheumatology
                          State Societies
------------------------------------------------------------------------
WEST PENN ALLEGHENY      Cardiovascular       02/17/2014      $10,000.00
 HEALTH SYSTEM, INC.      Medicine Update
------------------------------------------------------------------------
MEDSTAR WASHINGTON       12th International   02/18/2014      $25,000.00
 HOSPITAL CENTER          Congress on
                          Targeted
                          Anticancer
                          Therapies (TAT)
------------------------------------------------------------------------
THE BIBIKHAN FOUNDATION  7th Annual           02/18/2014       $5,000.00
                          Cardiovascular
                          Update--``A
                          Practical
                          Tutortial''
------------------------------------------------------------------------
SOCIETY OF GYNECOLOGIC   SGO 45th Annual      02/19/2014      $25,000.00
 ONCOLOGY                 Meeting on
                          Women's Cancer
------------------------------------------------------------------------
GORDON RESEARCH          Gordon Research      02/19/2014       $5,000.00
 CONFERENCES              Conferences on
                          Cardiac
                          Regulatory
                          Mechanisms
------------------------------------------------------------------------
BAYLOR UNIVERSITY        Emerging             02/20/2014      $17,460.00
 MEDICAL CENTER DBA A.    Therapeutic
 WEBB ROBERTS CENTER      Options for
                          Medullary Thyroid
                          Cancer and
                          Differentiated
                          Thyroid Cancer
------------------------------------------------------------------------
ACADEMIA MEDICA DEL SUR- Cardiometabolic      02/20/2014      $20,000.00
 FONDO EDUCACION MEDICA   Health Congress
 CONTINUADA               2014
------------------------------------------------------------------------
DUKE UNIVERSITY MEDICAL  13th Annual          02/25/2014       $5,498.41
 CENTER                   Southeastern
                          Fellows Research
                          Skills Retreat
------------------------------------------------------------------------
THE UNIVERSITY OF        19th Annual          02/25/2014       $5,000.00
 CHICAGO                  University of
                          Chicago Phase II
                          Consortium (UC
                          P2C) Symposium
------------------------------------------------------------------------
INTERNATIONAL SOCIETY    60th Annual          02/25/2014      $25,000.00
 ON THROMBOSIS AND        Meeting of the
 HAEMOSTASIS              Scientific and
                          Standardization
                          Committee (SSC)
                          of the
                          International
                          Society on
                          Thrombosis and
                          Haemostasis
                          (ISTH)
------------------------------------------------------------------------
THE UNIVERSITY OF        Making Sense of      02/25/2014       $5,000.00
 CHICAGO                  the Sequence:
                          Genomics Primer
                          for Clinical
                          Cancer Genetic
                          Practitioners
------------------------------------------------------------------------
WEST VIRGINIA ACADEMY    Dyslipidemia and     02/25/2014       $2,500.00
 OF FAMILY PHYSICIANS     Atherosclerosis--
                          Reducing the Risk
------------------------------------------------------------------------
AMERICAN ACADEMY OF      PediaLink            02/26/2014      $37,800.00
 PEDIATRICS               Influenza Course
                          Series
------------------------------------------------------------------------
PREVENTIVE               20th Annual          02/26/2014      $15,000.00
 CARDIOVASCULAR NURSES    Symposium
 ASSOCIATION
------------------------------------------------------------------------
NATIONAL ASSOCIATION OF  2014 NAFC Annual     02/27/2014      $30,000.00
 FREE and CHARITABLE      Summit
 CLINICS
------------------------------------------------------------------------
VANDERBILT UNIVERSITY    Cardiology 2014:     02/27/2014       $5,000.00
                          Advances in
                          Science and
                          Practice
------------------------------------------------------------------------
THE BOARD OF REGENTS OF  Cardiovascular       02/27/2014       $5,000.00
 THE UNIVERSITY OF        Medicine and
 WISCONSIN SYSTEM         Prevention Update
                          for Primary Care
------------------------------------------------------------------------
SOCIETY FOR VASCULAR     Society for          03/02/2014       $5,000.00
 MEDICINE                 Vascular Medicine
                          25th Anniversary
                          and Scientific
                          Sessions
------------------------------------------------------------------------
AMERICAN ASSOCIATION     94th Annual          03/04/2014      $10,000.00
 FOR THORACIC SURGERY     Meeting American
                          Association for
                          Thoracic Surgery
------------------------------------------------------------------------
CHI ST. LUKE'S HEALTH    Cardiology Grand     03/05/2014       $3,857.58
                          Rounds
------------------------------------------------------------------------
MIDWEST CARDIOVASCULAR   Cardiovascular       03/05/2014       $5,000.00
 RESEARCH FOUNDATION      Interventions and
                          Practice
                          Guidelines
------------------------------------------------------------------------
UNIVERSITY OF ROCHESTER  27th Cardiology      03/05/2014       $4,805.00
                          Spring Update
                          2014
------------------------------------------------------------------------
UNIVERSITY OF            Clinical             03/05/2014       $4,000.00
 WASHINGTON               Cardiology Pearls
                          for Primary Care
                          Providers
------------------------------------------------------------------------
AMERICAN ACADEMY OF      Faces and Cases:     03/06/2014      $50,000.00
 PAIN MANAGEMENT          Assessing and
                          Managing People
                          With Complex
                          Chronic Pain
------------------------------------------------------------------------
PRESIDENT AND FELLOWS    Pediatric Asthma     03/06/2014       $5,000.00
 OF HARVARD COLLEGE       and Allergy
                          Updates for
                          Primary Care
                          Providers
------------------------------------------------------------------------
PRESIDENT AND FELLOWS    Boston Bacterial     03/06/2014       $2,500.00
 OF HARVARD COLLEGE       Meeting 2014
------------------------------------------------------------------------
CARDIOVASCULAR RESEARCH  TCTMD 2014 Post      03/09/2014     $100,000.00
 FOUNDATION               Conference Web
                          Cast Series
------------------------------------------------------------------------
CARDIOVASCULAR RESEARCH  DAPT Dilemmas: A     03/09/2014      $66,913.46
 FOUNDATION               Case-based
                          Roundtable
                          Tutorial
------------------------------------------------------------------------
ASSOCIATION OF BLACK     40th Anniversary     03/11/2014      $20,000.00
 CARDIOLOGISTS            Annual Scientific
                          Sessions The
                          Ecology of
                          Cardiovascular
                          Disease in 2014:
                          Trends,
                          Challenges and
                          Targets for 2025
------------------------------------------------------------------------
THE HOPE FOUNDATION      Spring 2014 SWOG     03/18/2014      $10,000.00
                          Group Meeting
------------------------------------------------------------------------
AMERICAN LUNG            ALASD Asthma         03/18/2014       $2,500.00
 ASSOCIATION OF THE       Educator
 UPPER MIDWEST            Institute
------------------------------------------------------------------------
AMERICAN SOCIETY OF      Getting to Goal:     03/19/2014       $5,950.00
 CONSULTANT PHARMACISTS   The Pharmacist's
 FL CHAPTER               Role in Managing
                          Dyslipidemia and
                          Atherosclerosis
------------------------------------------------------------------------
THE RESEARCH FOUNDATION  Cal For Grants CGA   03/19/2014       $2,000.00
                          CV 1404--Time
                          Critical
                          Diagnosis (TCD)
                          Symposium
------------------------------------------------------------------------
EMORY UNIVERSITY         Emory Practical      03/19/2014       $3,000.00
                          Intervention
                          Course (EPIC
                          2014)
------------------------------------------------------------------------
GORDON RESEARCH          Gordon Research      03/20/2014       $5,000.00
 CONFERENCES              Conference and
                          Seminar on
                          Hemostasis
------------------------------------------------------------------------
PENNSYLVANIA ALLERGY     2014 Annual          03/20/2014       $5,000.00
 AND ASTHMA ASSOCIATION   Meeting of the
                          Pennsylvania
                          Allergy and
                          Asthma
                          Association
------------------------------------------------------------------------
ONCOLOGY NURSING         Oncology Nursing     03/20/2014      $25,000.00
 SOCIETY                  Society 39th
                          Annual Congress
------------------------------------------------------------------------
RICHMOND UNIVERSITY      Lipid Management     03/20/2014       $1,400.00
 MEDICAL CENTER           2014 Guidelines
                          and Beyond
------------------------------------------------------------------------
JOHNS HOPKINS            5th Annual Johns     03/23/2014       $2,500.00
 UNIVERSITY               Hopkins
                          Cardiovascular
                          Research Retreat
------------------------------------------------------------------------
AMERICAN ACADEMY OF      Fall 2014            03/23/2014       $5,000.00
 ALLERGY ASTHMA AND       Symposium of the
 IMMUNOLOGY               Los Angeles
                          Society of
                          Allergy, Asthma
                          and Clinical
                          Immunology
------------------------------------------------------------------------
UNIVERSITY OF FLORIDA    Vascular Biology     03/23/2014      $15,000.00
                          Working Group US
                          Chapter Meeting
------------------------------------------------------------------------
THE SOCIETY FOR          2014 SCAI            03/23/2014      $15,000.00
 CARDIOVASCULAR           Transradial
 ANGIOGRAPHY AND          Interventional
 INTERVENTIONS            Program (TRIP)
                          Series
------------------------------------------------------------------------
ASPEN LUNG CONFERENCE    Thomas L. Petty      03/24/2014       $5,000.00
                          Aspen Lung
                          Conference:
                          Rebuilding the
                          Injured Lung
------------------------------------------------------------------------
INTERNATIONAL SOCIETY    ISHIB 2014 Annual    03/24/2014      $10,000.00
 ON HYPERTENSION IN       Conference-
 BLACKS INC.              Medical and
                          Social
                          Determinants of
                          Cardiometabolic
                          Health
------------------------------------------------------------------------
ARKANSAS ACADEMY OF      67th Annual          03/24/2014       $3,000.00
 FAMILY PHYSICIANS        Scientific
                          Assembly of the
                          Arkansas Academy
                          of Family
                          Physicians
------------------------------------------------------------------------
TRUSTEES OF THE          Current Advances     03/24/2014       $5,000.00
 UNIVERSITY OF            in Cardiovascular
 PENNSYLVANIA             Care 2014
------------------------------------------------------------------------
ST. PETER'S HOSPITAL     Cardiology           03/25/2014       $3,000.00
                          Teaching Day
------------------------------------------------------------------------
CHARLES R. DREW          18th Annual          03/26/2014      $25,000.00
 UNIVERSITY OF MEDICINE   Conference
 and SCIENCE
------------------------------------------------------------------------
GORDON RESEARCH          2014 GRC on          03/27/2014       $2,500.00
 CONFERENCES              Heterocyclic
                          Compounds
------------------------------------------------------------------------
THE ROCKEFELLER          Leptin and           03/30/2014      $25,000.00
 UNIVERSITY               Metabolic
                          Disease: A
                          Special Symposium
                          on the 20th
                          Anniversary of
                          the Discovery of
                          Leptin
------------------------------------------------------------------------
AMERICAN COLLEGE OF      CSAAI's A            03/30/2014       $5,000.00
 ALLERGY, ASTHMA AND      Midsummer Night's
 IMMUNOLOGY               Wheeze 2014
------------------------------------------------------------------------
UNIVERSITY OF NEW        PeerView Live,       04/01/2014     $353,000.00
 MEXICO                   Using Evidence-
                          Based Treatment
                          to Optimize
                          Control of
                          Elevated Serum
                          Triglycerides
                          (150202699)
------------------------------------------------------------------------
THOMAS JEFFERSON         Jefferson Critical   04/01/2014       $5,000.00
 UNIVERSITY               Care Symposium: A
                          Multidisciplinary
                          Review of Current
                          Evidence and
                          Controversies
------------------------------------------------------------------------
AMERICAN ASSOCIATION OF  35th Annual          04/01/2014       $3,000.00
 ENDOCRINE SURGEONS       Meeting of the
                          American
                          Association of
                          Endocrine
                          Surgeons
------------------------------------------------------------------------
GORDON RESEARCH          2014 Bioorganic      04/02/2014       $1,000.00
 CONFERENCES              Chemistry Gordon
                          Research
                          Conference
------------------------------------------------------------------------
THE NEW YORK             Seventh Annual       04/03/2014       $3,050.00
 CARDIOLOGICAL SOCIETY,   Cardiac Care
 INC.                     Associate
                          Symposium 2014
------------------------------------------------------------------------
CLEVELAND CLINIC         15th Annual          04/03/2014       $4,706.02
 EDUCATIONAL FOUNDATION   Intensive Review
                          of Cardiology
------------------------------------------------------------------------
WASHINGTON UNIVERSITY    Cardiology Update    04/06/2014       $4,000.00
------------------------------------------------------------------------
DIGNITY HEALTH ST.       16th Annual          04/06/2014       $6,000.00
 BERNARDINE MEDICAL       Cardiac Symposium
 CENTER
------------------------------------------------------------------------
CONQUER CANCER           2014 Conquer         04/09/2014      $24,000.00
 FOUNDATION OF THE        Cancer Foundation
 AMERICAN SOCIETY OF      of ASCO Merit
 CLINICAL ONCOLOGY        Awards
------------------------------------------------------------------------
MUNSTER MEDICAL          New Frontiers in     04/09/2014       $4,200.00
 RESEARCH FOUNDATION      Cardiovascular
 DBA COMMUNITY HOSPITAL   Disease 2014
------------------------------------------------------------------------
GORDON RESEARCH          2014 Gordon          04/09/2014       $2,000.00
 CONFERENCES              Research
                          Conference:
                          Enzymes CoEnzymes
                          and Metabolic
                          Pathways
------------------------------------------------------------------------
AMERICAN COLLEGE         2014 Mississippi/    04/09/2014       $5,000.00
 PHYSICIANS--MISSISSIPP   Louisiana ACP
 I CHAPTER                Educational and
                          Scientific
                          Meeting
------------------------------------------------------------------------
ICHAN SCHOOL OF          Live Symposium of    04/10/2014      $10,000.00
 MEDICINE AT MOUNT        Complex Coronary,
 SINAI                    Valvular and
                          Vascular Cases
------------------------------------------------------------------------
NATIONAL FOUNDATION FOR  Clinical             04/13/2014      $25,000.00
 INFECTIOUS DISEASES      Vaccinology
                          Course
------------------------------------------------------------------------
AMERICAN ACADEMY OF      The AAPA 2014        04/13/2014       $7,500.00
 PHYSICIAN ASSISTANTS     Annual
                          Conference--Cardi
                          ology Track
------------------------------------------------------------------------
NEW JERSEY ACADEMY OF    Cardiovascular       04/13/2014       $5,000.00
 FAMILY PHYSICIANS        Controversies
                          JNC8 and
                          Cholesterol
                          Treatment
                          Guidelines (2014
                          Scientific
                          Assembly)
------------------------------------------------------------------------
HUMBOLDT-DEL NORTE       Asthma Update        04/14/2014       $4,000.00
 COUNTY MEDICAL SOCIETY
------------------------------------------------------------------------
DANNEMILLER, INC.        Contemporary         04/16/2014      $50,000.00
                          Perspectives in
                          COPD: A
                          Pulmonologist's
                          Guide to
                          Individualized
                          Patient Care
------------------------------------------------------------------------
OKLAHOMA UNIVERSITY      17th Annual          04/16/2014       $3,000.00
 HEALTH SCIENCE CENTER--  Primary Care
 OUHSC                    Update
------------------------------------------------------------------------
CONQUER CANCER           2014 Conquer         04/17/2014      $60,000.00
 FOUNDATION OF THE        Cancer Foundation
 AMERICAN SOCIETY OF      of ASCO Young
 CLINICAL ONCOLOGY        Investigator
                          Award (YIA)
------------------------------------------------------------------------
CLEVELAND CLINIC         6th Annual E-        04/17/2014       $9,352.86
 EDUCATIONAL FOUNDATION   Journal Club: The
                          Insights on
                          Biologics and New
                          Agents for
                          Rheumatic
                          Diseases
------------------------------------------------------------------------
NATIONAL FOUNDATION FOR  17th Annual          04/21/2014      $15,000.00
 INFECTIOUS DISEASES      Conference on
                          Vaccine Research
------------------------------------------------------------------------
ECOG RESEARCH AND        2014 ECOG-ACRIN      04/21/2014       $5,000.00
 EDUCATION FOUNDATION     Spring Group
                          Meeting
------------------------------------------------------------------------
METABOLIC ENDOCRINE      Contemporary T2DM    04/21/2014     $229,200.00
 EDUCATION FOUNDATION     Management: Focus
                          on Safety and
                          Efficacy
------------------------------------------------------------------------
THE CHEST FOUNDATION     The CHEST            04/21/2014      $35,000.00
                          Foundation
                          Diversity
                          Research/Women's
                          Respiratory
                          Health Awards
                          Program
------------------------------------------------------------------------
MISSOURI ACADEMY OF      Hyperlipidemia       04/21/2014       $5,000.00
 PHYSICIAN ASSISTANTS
------------------------------------------------------------------------
REGENTS OF THE           Lipidomics Impact    04/22/2014       $2,500.00
 UNIVERSITY OF            on Cell Biology,
 CALIFORNIA, SAN DIEGO    Inflammation and
                          Metabolic Disease
------------------------------------------------------------------------
NATIONAL MINORITY        11th Annual          04/23/2014      $30,000.00
 QUALITY FORUM            National Summit
                          on Health
                          Disparities
------------------------------------------------------------------------
DUKE UNIVERSITY          2014 Carolinas       04/24/2014      $20,000.00
                          COPD Symposium
------------------------------------------------------------------------
MICHIGAN STATE MEDICAL   Rheumatology         04/24/2014       $3,000.00
 SOCIETY FOUNDATION       Update
------------------------------------------------------------------------
MAIN LINE HEALTH         Atherosclerosis:     04/24/2014       $5,000.00
                          Prevention of
                          Progression
------------------------------------------------------------------------
CASE MANAGEMENT SOCIETY  CMSA 2014 Annual     04/27/2014      $15,000.00
 OF AMERICA               Conference and
                          Expo
------------------------------------------------------------------------
NATIONAL COMPREHENSIVE   NCCN 2014 Monthly    04/27/2014      $25,000.00
 CANCER NETWORK, INC.     Oncology Tumor
                          Boards: A
                          Multidisciplinary
                          Approach to
                          Individualized
                          Patient Care
------------------------------------------------------------------------
AMERICAN HEART           Arteriosclerosis,    04/27/2014      $20,000.00
 ASSOCIATION, INC.        Thrombosis, and
                          Vascular Biology
                          Scientific
                          Sessions 2014
------------------------------------------------------------------------
SCRIPPS HEALTH           25th Annual          04/27/2014       $5,000.00
                          Cardiovascular
                          Interventions
------------------------------------------------------------------------
AMERICAN COLLEGE OF      Interventional       04/27/2014       $5,000.00
 CARDIOLOGY FOUNDATION    Cardiology Board
                          Preparatory
                          Educational
                          Package
------------------------------------------------------------------------
TEXAS ONE VOICE: A       Designing            04/28/2014       $1,000.00
 COLLABORATIVE FOR        Healthcare in
 HEALTH AND HUMAN         Texas How the
 SERVICES                 Past and Present
                          will Guide the
                          Future
------------------------------------------------------------------------
TRUSTEES OF THE          Cardiology Update    04/28/2014      $10,000.00
 UNIVERSITY OF            2014: A Patient
 PENNSYLVANIA             Management
                          Approach
------------------------------------------------------------------------
CONQUER CANCER           2014 ASCO Annual     05/04/2014      $56,000.00
 FOUNDATION OF THE        Meeting Lung
 AMERICAN SOCIETY OF      Cancer Track
 CLINICAL ONCOLOGY
------------------------------------------------------------------------
FOUNDATION FOR CARE      Dyslipidemia and     05/06/2014      $25,000.00
 MANAGEMENT               New Cholesterol
                          Guidelines: What
                          the Primary Care
                          Provider Needs to
                          Know
------------------------------------------------------------------------
AMERICAN COLLEGE OF      Update in Allergy,   05/06/2014      $10,000.00
 ALLERGY, ASTHMA AND      Asthma and
 IMMUNOLOGY               Immunology
------------------------------------------------------------------------
FLORIDA ACADEMY OF       Update in the        05/06/2014       $5,000.00
 PHYSICIAN ASSISTANTS     Management of
                          Dyslipidemia
------------------------------------------------------------------------
VASSAR BROTHERS MEDICAL  44th Annual          05/06/2014       $5,000.00
 CENTER                   Cardiology
                          Education Day
------------------------------------------------------------------------
ZOE ROSE MEMORIAL        2014 Preemie         05/06/2014      $10,000.00
 FOUNDATION DBA PREEMIE   Parent Summit
 PARENT ALLIANCE
------------------------------------------------------------------------
AMERICAN ASSOCIATION OF  AACE 23rd Annual     05/07/2014      $25,000.00
 CLINICAL                 Scientific and
 ENDOCRINOLOGISTS         Clinical Congress
------------------------------------------------------------------------
LOUISIANA SOCIETY OF     LSAAI 41st Annual    05/07/2014       $5,000.00
 ALLERGY, ASTHMA AND      Meeting
 IMMUNOLOGY
------------------------------------------------------------------------
AMERICAN ACADEMY OF      AAFP Assembly 60     05/07/2014      $13,000.00
 FAMILY PHYSICIANS        Minute Lecture
                          titled Chronic
                          Obstructive
                          Pulmonary
                          Disorder (COPD)
                          and Pulmonary
                          Function Testing
------------------------------------------------------------------------
COLUMBUS COMMUNITY       2014 ASCO REVIEW     05/08/2014       $5,000.00
 CLINICAL ONCOLOGY
 PROGRAM
------------------------------------------------------------------------
AMERICAN COLLEGE OF      Aspen Allergy        05/08/2014      $10,000.00
 ALLERGY, ASTHMA AND      Conference
 IMMUNOLOGY
------------------------------------------------------------------------
AMERICAN DIABETES        29th Annual          05/11/2014      $20,000.00
 ASSOCIATION              Clinical
                          Conference on
                          Diabetes--Reducin
                          g Risks: Primary
                          and Secondary
------------------------------------------------------------------------
REGENTS OF THE           20th Annual UCLA     05/11/2014       $5,000.00
 UNIVERSITY OF            Symposium
 CALIFORNIA               Pulmonary
                          Function and
                          Exercise Testing:
                          Practical
                          Approaches for
                          the Healthcare
                          Practitioner
------------------------------------------------------------------------
AMERICAN COLLEGE OF      The Changing         05/11/2014       $5,000.00
 ALLERGY, ASTHMA AND      Allergy Practice
 IMMUNOLOGY
------------------------------------------------------------------------
AMERICAN COLLEGE OF      Caribbean Congress   05/12/2014       $5,000.00
 EMERGENCY PHYSICIANS,    on Emergency
 PUERTO RICO CHAPTER      Medicine
------------------------------------------------------------------------
CLEVELAND CLINIC         19th Annual          05/13/2014       $6,613.34
 EDUCATIONAL FOUNDATION   Diabetes Day:
                          Diabetes Therapy
------------------------------------------------------------------------
THE REGENTS UNIVERSITY   UCLA Family          05/13/2014       $7,500.00
 OF CALIFORNIA            Medicine
                          Refresher Course
------------------------------------------------------------------------
CLEVELAND CLINIC         ASCO Review          05/13/2014       $4,000.00
 EDUCATIONAL FOUNDATION
------------------------------------------------------------------------
SOCIEDAD PUERTORRIQUENA  Puerto Rican         05/14/2014      $10,000.00
 DE ENDOCRINOLOGIA Y      Endocrinology and
 DIABETOLOGIA             Diabetes Society
                          Scientific
                          Meeting
------------------------------------------------------------------------
NATIONAL MEDICAL         Asthma as a Model    05/14/2014      $25,000.00
 ASSOCIATION              Chronic Illness
------------------------------------------------------------------------
GORDON RESEARCH          2014 Lipoprotein     05/14/2014       $2,500.00
 CONFERENCES              Metabolism Gordon
                          Research
                          Conference
------------------------------------------------------------------------
ONCOLOGY NURSING         Pharmacology         05/14/2014       $5,000.00
 SOCIETY                  Update:Integratin
                          g Advances into
                          Practice
------------------------------------------------------------------------
AMERICAN ASSOCIATION OF  2014 National        05/14/2014       $5,000.00
 SERVICE COORDINATORS     Service
                          Coordinator
                          Conference
------------------------------------------------------------------------
MAYO CLINIC ARIZONA      Cardiology Update    05/15/2014      $10,000.00
                          2014: The Heart
                          of the Matter
------------------------------------------------------------------------
AMERICAN CHEMICAL        2014 ACS National    05/18/2014       $1,000.00
 SOCIETY--DIVISION OF     Medicinal
 MEDICINAL CHEMISTRY      Chemistry
                          Symposium
------------------------------------------------------------------------
CHICAGO ASTHMA           Emergency            05/18/2014       $2,000.00
 CONSORTIUM               Management of
                          Asthma
------------------------------------------------------------------------
SUFFOLK ACADEMY OF       31st Update in       05/19/2014       $3,000.00
 MEDICINE                 Allergy and
                          Immunology
                          Symposium
------------------------------------------------------------------------
EMORY UNIVERSITY         Discussing Cases     05/19/2014      $20,000.00
                          with Diabetes
                          Experts
------------------------------------------------------------------------
NATIONAL MEDICAL         Evidence-Based       05/19/2014      $23,405.00
 ASSOCIATION              Diagnosis and
                          Management of
                          Asthma and COPD:
                          Practical Tools
                          to Improve
                          Patient Care
------------------------------------------------------------------------
NORTH SHORE LONG ISLAND  Post American        05/19/2014       $3,000.00
 JEWISH HEALTH SYSTEM     Society of
                          Clinical Oncology
                          Update 2014
------------------------------------------------------------------------
LAHEY CLINIC HOSPITAL,   Cardiovascular       05/19/2014       $6,000.00
 INC.                     Disease: State of
                          the Art 2014
------------------------------------------------------------------------
AMERICAN COLLEGE OF      2014                 05/19/2014       $5,000.00
 CARDIOLOGY FOUNDATION    Cardiovascular
                          Board Review for
                          Certification and
                          Recertification
                          Educational
                          Package
------------------------------------------------------------------------
NEW JERSEY ACADEMY OF    The Current          05/21/2014       $2,500.00
 FAMILY PHYSICIANS        Standards Of Care
                          and Treatment of
                          Diabetes (2014
                          Scientific
                          Assembly)
------------------------------------------------------------------------
CONQUER CANCER           2014 Conquer         05/21/2014     $250,000.00
 FOUNDATION OF THE        Cancer Foundation
 AMERICAN SOCIETY OF      of ASCO Career
 CLINICAL ONCOLOGY        Development Award
                          (CDA)
------------------------------------------------------------------------
NORTHWESTERN UNIVERSITY  16th Annual Lynn     05/21/2014      $10,000.00
                          Sage Breast
                          Cancer Symposium
------------------------------------------------------------------------
PENNSYLVANIA SOCIETY OF  Lipid Management     05/21/2014       $5,000.00
 PHYSICIAN ASSISTANTS     The Skinny on the
                          Fat
------------------------------------------------------------------------
DUKE UNIVERSITY          1st Annual Duke      05/29/2014      $10,000.00
                          Preventive
                          Cardiology
                          Symposium
------------------------------------------------------------------------
ALZHEIMER'S ASSOCIATION  2014 Alzheimer's     05/29/2014      $95,000.00
                          Association
                          International
                          Conference
------------------------------------------------------------------------
TRUSTEES OF THE          2014 Updates in      05/29/2014       $5,000.00
 UNIVERSITY OF            Oncology: With
 PENNSYLVANIA             Proceedings from
                          International
                          Medical Meetings
------------------------------------------------------------------------
SOCIETY FOR              Young Investigator   06/01/2014      $25,000.00
 NEUROSCIENCE             Award
------------------------------------------------------------------------
METABOLIC ENDOCRINE      The Role of the      06/03/2014     $149,025.00
 EDUCATION FOUNDATION     Kidney in Glucose
                          Homeostasis and
                          Diabetes
------------------------------------------------------------------------
VIVA PHYSICIANS          VIVA 14: Vascular    06/03/2014      $20,000.00
                          InterVentional
                          Advances
------------------------------------------------------------------------
SOCIETY OF TOXICOLOGIC   Translational        06/04/2014       $3,000.00
 PATHOLOGY                Pathology:
                          Relevance of
                          Toxicologic
                          Pathology to
                          Human Health
------------------------------------------------------------------------
UHS PROFESSIONAL         Gout and             06/04/2014     $100,825.00
 EDUCATION PROGRAMS,      Hyperuricemia--Cl
 INC.                     inical Spectrum
                          and Management
                          Update
------------------------------------------------------------------------
AMERICAN ACADEMY OF      AAFP Assembly 60     06/04/2014      $10,000.00
 FAMILY PHYSICIANS        Minute Lecture
                          titled Acute
                          Coronary Syndrome
                          and Angina
                          (Fundamentals)
------------------------------------------------------------------------
AMERICAN ACADEMY OF      AAFP Assembly 60     06/04/2014      $10,000.00
 FAMILY PHYSICIANS        Minute Lecture
                          titled Acute
                          Coronary Syndrome
                          and Angina
                          (Advanced)
------------------------------------------------------------------------
THE NEPHCURE FOUNDATION  10th International   06/04/2014       $5,000.00
                          Podocyte
                          Conference
------------------------------------------------------------------------
ICAHN SCHOOL OF          Mount Sinai          06/09/2014       $2,500.00
 MEDICINE AT MOUNT        Division of
 SINAI                    Occupational
                          Medicine seminar
                          series
------------------------------------------------------------------------
SWEDISH MEDICAL CENTER   Cardiology Update    06/09/2014       $5,000.00
 FOUNDATION               for Primary Care
------------------------------------------------------------------------
JOSLIN DIABETES CENTER   The Institute of     06/11/2014      $15,000.00
                          Lifestyle
                          Medicine 2014
                          Educational
                          Activities
------------------------------------------------------------------------
CARDIOVASCULAR RESEARCH  ACS/STEMI: Focus     06/11/2014      $60,000.00
 FOUNDATION               on Acute Care
------------------------------------------------------------------------
PENN STATE COLLEGE OF    20th Annual          06/18/2014       $7,000.00
 MEDICINE                 Pennsylvania
                          Immunization
------------------------------------------------------------------------
AMERICAN SOCIETY FOR     ASPMN 24th           06/18/2014      $10,000.00
 PAIN MANAGEMENT          National
 NURSING                  Conference
------------------------------------------------------------------------
AMERICAN PHARMACISTS     APhA Pharmacy-       06/18/2014       $2,500.00
 ASSOCIATION              Based
                          Immunization
                          Delivery
------------------------------------------------------------------------
WASHINGTON UNIVERSITY    Mentors in           06/22/2014      $50,000.00
                          Medicine
------------------------------------------------------------------------
PONCE MEDICAL SCHOOL     Advances in          06/24/2014       $5,000.00
 FOUNDATION INC.          Dyslipidemia and
                          Atherosclerosis
                          Management
------------------------------------------------------------------------
AMERICAN COLLEGE OF      Cardiovascular       06/25/2014      $15,000.00
 EMERGENCY PHYSICIANS     Disease Track at
                          ACEP 2014
                          Scientific
                          Assembly
------------------------------------------------------------------------
THE BRIGHAM AND WOMEN'S  BWH Thyroid          06/26/2014       $3,000.00
 HOSPITAL INC.            Visiting
                          Professor and
                          Endocrine Grand
                          Rounds Speaker
------------------------------------------------------------------------
WASHINGTON UNIVERSITY    Clinical Allergy     06/26/2014       $5,000.00
                          for the
                          Practicing
                          Physician
------------------------------------------------------------------------
PREVENTIVE               Fall Programs        06/26/2014       $5,000.00
 CARDIOVASCULAR NURSES
 ASSOCIATION
------------------------------------------------------------------------
GORDON RESEARCH          2014 Gordon          06/26/2014         $500.00
 CONFERENCES              Research Seminar
                          on Synaptic
                          Transmission
------------------------------------------------------------------------
GREENWOOD LEFLORE        Call for Grants:     06/29/2014       $2,500.00
 HOSPITAL                 CGA Educating the
                          Delta on
                          Asthmatic
                          Patients
------------------------------------------------------------------------
GORDON RESEARCH          Gordon Research      06/29/2014       $2,000.00
 CONFERENCE               Conference on
                          Multi-Drug Efflux
                          Systems
------------------------------------------------------------------------
GORDON RESEARCH          Gordon Research      06/29/2014       $2,000.00
 CONFERENCES              Conference: DNA
                          Topoisomerases in
                          Biology and
                          Medicine
------------------------------------------------------------------------
ALBANY COLLEGE OF        Heart to Heart:      06/30/2014      $14,000.00
 PHARMACY AND HEALTH      Updates on
 SCIENCES                 Cardiovascular
                          Disease and the
                          Management of
                          Cholesterol and
                          Hypertension
------------------------------------------------------------------------
CANCER MOLECULAR         Molecular            06/30/2014       $5,000.00
 THERAPEUTICS RESEARCH    Therapeutics of
 ASSOCIATION              Cancer Conference
                          2014
------------------------------------------------------------------------
VANDERBILT UNIVERSITY    Vanderbilt           07/08/2014       $3,000.00
                          University
                          Hematology
                          Oncology
                          Educational
                          Symposium
------------------------------------------------------------------------
CHILDREN'S HOSPITAL      Translating Neural   07/08/2014       $3,000.00
 CORPORATION              Circuits and
                          Pathways into
                          Treatments
------------------------------------------------------------------------
PENNSYLVANIA SOCIETY OF  Breast Cancer-       07/09/2014       $3,000.00
 PHYSICIAN ASSISTANTS     Fight Like a Girl
------------------------------------------------------------------------
PROMEDICA ACADEMIC       After the            07/09/2014       $2,500.00
 HEALTH CENTER            Diagnosis:
 CORPORATION              Helping
                          Cardiopulmonary
                          Patients Succeed--
                          Approaches to
                          Stay Ahead of the
                          Curve
------------------------------------------------------------------------
CONQUER CANCER           2014 Breast Cancer   07/09/2014      $10,000.00
 FOUNDATION OF THE        Symposium
 AMERICAN SOCIETY OF
 CLINICAL ONCOLOGY
------------------------------------------------------------------------
NURSE PRACTITIONER       Hyperlipidemia and   07/09/2014       $5,000.00
 ASSOC. FOR CONTINUING    Hypertension in
 EDUCATION                2014: What's New
                          in Treatment
                          Guidelines
------------------------------------------------------------------------
DIABLO SOCIETY OF        Cost-Effective       07/10/2014       $5,600.00
 HEALTH SYSTEM            Genotype-Guided
 PHARMACISTS              Antiplatelet
                          Therapy with
                          Ticagrelor
------------------------------------------------------------------------
ALAMO CITY CANCER        12th Annual Breast   07/10/2014       $1,500.00
 COUNCIL                  Cancer Conference
                          Update
------------------------------------------------------------------------
UNIVERSITY OF TEXAS      37TH Annual San      07/10/2014      $10,000.00
 HEALTH SCIENCE CENTER    Antonio Breast
 SAN ANTONIO SCHOOL OF    Cancer Symposium
 MEDICINE
------------------------------------------------------------------------
NATIONAL ASSOCIATION OF  Best Practices in    07/15/2014      $25,000.00
 MANAGED CARE             the Prevention
 PHYSICIANS               and Management of
                          Chronic
                          Obstructive
                          Pulmonary Disease
                          (COPD)
------------------------------------------------------------------------
CEDARS-SINAI MEDICAL     Advances in Care     07/17/2014       $3,000.00
 CENTER                   for the New
                          Millennium: 20th
                          Anniversary BRCA
                          Gene Symposium
------------------------------------------------------------------------
NATIONAL ASSOCIATION OF  Current Treatments   07/17/2014      $25,000.00
 MANAGED CARE             and Novel
 PHYSICIANS               Strategies in the
                          Management of
                          Acute Coronary
                          Syndrome (ACS)
------------------------------------------------------------------------
MARSHA RIVKIN CENTER     10th Biennial        07/22/2014       $5,000.00
 FOR OVARIAN CANCER       Ovarian Cancer
 RESEARCH                 Research
                          Symposium
------------------------------------------------------------------------
FLORIDA ASSOCIATION OF   Optimizing Oral      07/22/2014       $9,600.00
 CONSULTANT PHARMACISTS   Antiplatelet
                          Therapy in Acute
                          Coronary Syndrome
------------------------------------------------------------------------
AMERICAN COLLEGE OF      Foundations for      07/22/2014      $10,000.00
 CARDIOLOGY FOUNDATION    Practice
                          Excellence: Core
                          Curriculum for
                          the
                          Cardiovascular
                          Clinician 2014
------------------------------------------------------------------------
METABOLIC ENDOCRINE      12th Annual World    07/23/2014     $100,000.00
 EDUCATION FOUNDATION     Congress on
                          Insulin
                          Resistance
                          Diabetes and
                          Cardiovascular
                          Disease--WCIRDC
------------------------------------------------------------------------
AMERICAN ASSOCIATION OF  Program Title        07/23/2014       $3,000.00
 ENDOCRINE SURGEONS       Masters Course in
 FOUNDATION               Endocrine Surgery
------------------------------------------------------------------------
CARDIOVASCULAR RESEARCH  Acute Coronary       07/24/2014      $20,000.00
 FOUNDATION               Syndromes,
                          Pharmacotherapy
                          and Shock/
                          Hemodynamic
                          Support
------------------------------------------------------------------------
CARDIOVASCULAR RESEARCH  Town Hall and        07/24/2014      $20,000.00
 FOUNDATION FDA           Clinical Trial
                          Design and
                          Interpretation
------------------------------------------------------------------------
MINNESOTA PHARMACISTS    MPhA Annual          07/24/2014       $2,150.00
 ASSOCIATION              Meeting: MTM in
                          Cardiology Clinic
------------------------------------------------------------------------
AMERICAN ACADEMY OF      6th Annual           07/29/2014       $5,000.00
 PHYSICIAN ASSISTANTS     Allergy, Asthma
 IN ALLERGY, ASTHMA AND   and ENT CME
 IMMUNOLOGY               Conference
------------------------------------------------------------------------
AMERICAN COLLEGE OF      Severe Asthma        07/29/2014      $22,000.00
 ALLERGY, ASTHMA AND      Workshop at the
 IMMUNOLOGY               2014 ACAAI Annual
                          Scientific
                          Meeting
------------------------------------------------------------------------
INTERNATIONAL            16th World           07/29/2014      $30,000.00
 ASSOCIATION FOR THE      Conference on
 STUDY OF LUNG CANCER     Lung Cancer
------------------------------------------------------------------------
AMERICAN COLLEGE OF      The Affordable       07/29/2014      $22,000.00
 ALLERGY, ASTHMA AND      Care Act and
 IMMUNOLOGY               Asthma Control
------------------------------------------------------------------------
DANA-FARBER CANCER       Dana-Farber Cancer   07/31/2014       $2,400.00
 INSTITUTE                Institute's 10th
                          Annual
                          Postdoctoral and
                          Graduate Student
                          Retreat
------------------------------------------------------------------------
NATIONAL ASSOCIATION     2014 NAHQ 39th       07/31/2014      $15,000.00
 FOR HEALTHCARE QUALITY   Annual
                          Educational
                          Conference
------------------------------------------------------------------------
ICAHN SCHOOL OF          2014 Top Ten         07/31/2014      $10,000.00
 MEDICINE AT MOUNT        Advances in
 SINAI                    Clinical
                          Cardiology
------------------------------------------------------------------------
AMERICAN COLLEGE OF      COPD/Asthma Track    07/31/2014      $25,800.00
 CHEST PHYSCIANS          at CHEST 2014
------------------------------------------------------------------------
DREXEL UNIVERSITY        Hypertension         08/03/2014       $5,000.00
                          HighLights-ASH
                          2014
------------------------------------------------------------------------
ASSOCIATION OF           No Gout About It:    08/03/2014       $9,500.00
 REPRODUCTIVE HEALTH      Targeted Provider
 PROFESSIONALS            Education and
                          Training to
                          Screen,
                          Diagnosis, and
                          Manage Gout among
                          Female Patients
------------------------------------------------------------------------
AMERICAN ASSOCIATION     AACR Tumor           08/03/2014      $10,000.00
 FOR CANCER RESEARCH      Immunology and
                          Immunotherapy: A
                          New Chapter
------------------------------------------------------------------------
THE OHIO STATE           Sixth Annual         08/05/2014       $5,000.00
 UNIVERSITY               Contemporary
                          Multidisciplinary
                          Cardiovascular
                          Conference
------------------------------------------------------------------------
WAYNE STATE UNIVERSITY   Update in            08/05/2014       $5,000.00
                          Rheumatology
------------------------------------------------------------------------
AMERICAN COLLEGE OF      COPD Interactive     08/06/2014      $20,000.00
 CHEST PHYSICIANS         Educational Game
------------------------------------------------------------------------
NATIONAL ASSOCIATION OF  Updates in the       08/06/2014      $25,000.00
 MANAGED CARE             Treatment of
 PHYSICIANS, INC.         Hypertriglyceride
                          mia: A Closer
                          Look at the Role
                          of Omega-3 Fatty
                          Acids
------------------------------------------------------------------------
NATIONAL JEWISH HEALTH   19th Annual Allied   08/07/2014       $2,500.00
                          Health Regional
                          Conference
------------------------------------------------------------------------
WESTERN SOCIETY OF       WSAAI 53rd Annual    08/07/2014      $15,000.00
 ALLERGY, ASTHMA AND      Scientific
 IMMUNOLOGY               Session
------------------------------------------------------------------------
DELAWARE ACADEMY OF      Acute Coronary       08/07/2014       $3,500.00
 PHYSICIAN ASSISTANTS     Syndromes: Acute
                          Myocardial
                          Infarction and
                          Unstable Angina
------------------------------------------------------------------------
AMERICAN PHARMACISTS     Addressing Racial    08/10/2014      $25,000.00
 ASSOCIATION              and Ethnic
                          Healthcare
                          Disparities in
                          Diabetes
------------------------------------------------------------------------
THOMAS JEFFERSON         Current Issues in    08/10/2014      $10,000.00
 UNIVERSITY               Coronary and
                          Structural Heart
                          Disease: A
                          Multidisciplinary
                          Approach
------------------------------------------------------------------------
UNIVERSITY OF            University of        08/11/2014       $5,000.00
 WASHINGTON CME OFFICE    Washington Topics
                          in Allergy and
                          Immunology
                          Teaching Series
                          2014-2015
------------------------------------------------------------------------
FOUNDATION OF THE        The Foundation of    08/11/2014      $50,000.00
 NATIONAL LIPID           the National
 ASSOCIATION              Lipid Association
                          Hunninghake FH
                          Abstract Award
------------------------------------------------------------------------
NATIONAL ASSOCIATION OF  NANN 30th Annual     08/13/2014      $10,000.00
 NEONATAL NURSES          Educational
                          Conference
------------------------------------------------------------------------
AMERICAN SOCIETY FOR     ASTRO 56th Annual    08/17/2014       $3,000.00
 RADIATION ONCOLOGY       Meeting
 (ASTRO)
------------------------------------------------------------------------
AMERICAN SOCIETY OF      SGLT2 Inhibitor      08/17/2014     $170,000.00
 NEPHROLOGY               Therapy in
                          Patients with
                          Mild to Moderate
                          Diabetic Kidney
                          Disease
------------------------------------------------------------------------
PRESIDENT AND FELLOWS    Multidisciplinary    08/17/2014       $4,500.00
 OF HARVARD COLLEGE       Breast Rounds
------------------------------------------------------------------------
METABOLIC ENDOCRINE      Contemporary T2DM    08/17/2014     $376,125.00
 EDUCATION FOUNDATION     Management: Focus
                          on Safety and
                          Efficacy (Live
                          Program)
------------------------------------------------------------------------
MISSISSIPPI HEALTHCARE   STEMI Protocols      08/17/2014       $1,464.83
 ALLIANCE
------------------------------------------------------------------------
AMERICAN ASSOCIATION OF  Practical            08/19/2014     $144,399.00
 DIABETES EDUCATORS       Applications of
                          Pramlintide in
                          Type 1 Diabetes
------------------------------------------------------------------------
AMERICAN SOCIETY OF      Novel Treatments     08/19/2014     $252,000.00
 HEALTH-SYSTEM            for the
 PHARMACISTS              Management of
                          Type 2 Diabetes:
                          Focus on SGLT2
                          Inhibitors
------------------------------------------------------------------------
THE SOCIETY FOR          SCAI 2014            08/19/2014      $50,000.00
 CARDIOVASCULAR           Interventional
 ANGIOGRAPHY AND          Cardiology
 INTERVENTIONS            Fellows Courses
------------------------------------------------------------------------
OLIGONUCLEOTIDE          10th Annual          08/19/2014      $10,000.00
 THERAPEUTICS SOCIETY     Meeting of the
                          Oligonucleotide
                          Therapeutics
                          Society
------------------------------------------------------------------------
SOCIETY FOR THE          Advances in Cancer   08/19/2014      $75,000.00
 IMMUNOTHERAPY OF         Immunotherapy--Se
 CANCER                   ries of 5
                          Regional Programs
------------------------------------------------------------------------
AMERICAN ACADEMY OF      The Sixth Annual     08/19/2014       $7,500.00
 PHYSICIAN ASSISTANTS     Hospital Medicine
                          Boot Camp
------------------------------------------------------------------------
UNIVERSITY OF            CAll for Grants      08/21/2014      $25,800.00
 CINCINNATI               Application (CGA)
                          CV14-1st Annual
                          Cincinnati
                          Collaborative
                          Cardiovascular
                          Consortium (C4):
                          Practical and
                          Contemporary
                          Cardiology 2014
------------------------------------------------------------------------
WAYNE STATE UNIVERSITY   Pulmonary,           08/27/2014       $3,000.00
                          Critical Care and
                          Sleep Medicine
                          Update 2014
------------------------------------------------------------------------
INTERNATIONAL SOCIETY    ISAM Textbook of     08/27/2014      $10,000.00
 FOR AEROSOLS IN          Aerosol Medicine
 MEDICINE
------------------------------------------------------------------------
NURSE PRACTITIONER       Asthma and COPD      08/27/2014       $5,000.00
 ASSOCIATES FOR           2014
 CONTINUING EDUCATION
 (NPACE)
------------------------------------------------------------------------
AMERICAN COLLEGE OF      CHEST 2014 Lung      08/27/2014      $24,150.00
 CHEST PHYSCIANS          Cancer Track
------------------------------------------------------------------------
THE UNIVERSITY OF TEXAS  Medical Oncology     08/28/2014       $3,000.00
 MD ANDERSON CANCER       and Hematology
 CENTER                   2014:
                          Multidisciplinary
                          Approaches that
                          Improve
                          Coordination of
                          Care
------------------------------------------------------------------------
NATIONAL JEWISH HEALTH   37th Annual          08/28/2014       $5,000.00
                          Pulmonary and
                          Allergy Update
------------------------------------------------------------------------
NOT-FOR-PROFIT HOSPITAL  Management and       08/28/2014       $2,400.00
 CORPORATION              Prevention of
                          Acute
                          Exacerbation of
                          COPD (AECOPD)
------------------------------------------------------------------------
AMERICAN ASSOCIATION OF  New Jersey--AACE     08/31/2014       $5,000.00
 CLINICAL                 7th Annual
 ENDOCRINOLOGISTS         Meeting
------------------------------------------------------------------------
WILLIAM BEAUMONT         Practical and        08/31/2014       $2,000.00
 HOSPITAL                 Progressive
                          Updates in
                          Primary Care
                          Medicine
------------------------------------------------------------------------
AMERICAN COLLEGE OF      47th Annual New      08/31/2014      $15,000.00
 CARDIOLOGY FOUNDATION    York
                          Cardiovascular
                          Symposium: Major
                          Topics in
                          Cardiology Today
------------------------------------------------------------------------
INTERNATIONAL            IASLC Fellowships    09/02/2014      $43,000.00
 ASSOCIATION FOR THE
 STUDY OF LUNG CANCER
------------------------------------------------------------------------
RUTGERS, THE STATE       Update in            09/02/2014       $7,500.00
 UNIVERSITY OF NEW        Rheumatology 2014
 JERSEY
------------------------------------------------------------------------
CHILDREN'S HEALTHCARE    Respiratory Update   09/02/2014       $3,000.00
 OF ATLANTA               2014
------------------------------------------------------------------------
UNIVERSITY OF MARYLAND,  Patient-Focused      09/02/2014      $10,000.00
 BALTIMORE FOUNDATION     Drug Development
------------------------------------------------------------------------
THE ANGIOGENESIS         World Congress on    09/02/2014       $5,000.00
 FOUNDATION               Angiogenesis
------------------------------------------------------------------------
JOHNS HOPKINS            New Therapeutic      09/02/2014      $20,000.00
 UNIVERSITY               Insights/Advances
                          in Allergic
                          Diseases
------------------------------------------------------------------------
GORDON RESEARCH          Mammalian DNA        09/02/2014       $5,000.00
 CONFERENCES              Repair Gordon
                          Research
                          Conference and
                          Seminar 2015
------------------------------------------------------------------------
ILLINOIS ACADEMY OF      Health Care Reform   09/04/2014       $2,000.00
 FAMILY PHYSICIANS        and Care
                          Coordination
------------------------------------------------------------------------
EXCELLENCE IN            Rheumatology         09/04/2014      $25,000.00
 RHEUMATOLOGY EDUCATION   Winter Clinical
                          Symposium 2015
------------------------------------------------------------------------
SOCIETY OF INFECTIOUS    Society of           09/04/2014       $5,000.00
 DISEASES PHARMACISTS     Infectious
                          Diseases
                          Pharmacists
                          Research Grant
                          Program
------------------------------------------------------------------------
CARDIOVASCULAR           CVIs 21st Annual     09/09/2014      $10,000.00
 INSTITUTE OF             Cardiology
 PHILADELPHIA             Update: Clinical
                          Management of
                          Heart Disease
                          2014
------------------------------------------------------------------------
PROVIDENCE HOLY CROSS    Acute Coronary       09/09/2014       $1,900.00
 MEDICAL CENTER           Syndrome
------------------------------------------------------------------------
DUKE UNIVERSITY          14th Annual          09/14/2014      $10,000.00
                          Southeastern
                          Fellows Research
                          Skills and
                          Training Workshop
------------------------------------------------------------------------
PHILLIPS GILMORE         Atlanta Lung         09/14/2014       $3,000.00
 ONCOLOGY                 Cancer Symposium
 COMMUNICATIONS, INC.     2014
------------------------------------------------------------------------
ECOG RESEARCH AND        2014 ECOG-ACRIN      09/14/2014       $5,000.00
 EDUCATION FOUNDATION     Fall Group
                          Meeting
------------------------------------------------------------------------
THE NEW YORK ACADEMY OF  Pharmacologic        09/14/2014      $10,000.00
 SCIENCES                 Resolution of
                          Inflammation as a
                          Novel Therapeutic
                          Approach
------------------------------------------------------------------------
MEDICAL COLLEGE OF       8th Annual           09/15/2014       $3,000.00
 WISCONSIN                Translational
                          Oncology Research
                          Symposium
------------------------------------------------------------------------
FRIENDS OF CANCER        Friends of Cancer    09/15/2014     $100,000.00
 RESEARCH                 Research 2014
                          programs
------------------------------------------------------------------------
UNIVERSITY OF FLORIDA    Vascular Biology     09/15/2014      $15,000.00
                          Working Group
                          Global Chapter
                          Meting
------------------------------------------------------------------------
ORLANDO HEALTH           Advancements in      09/15/2014       $3,000.00
                          the Early
                          Detection and
                          Treatment of
                          Breast and
                          Gynecologic
                          Malignancies
------------------------------------------------------------------------
YALE UNIVERSITY          Severe Asthma        09/17/2014       $5,000.00
                          2014: A
                          Personalized
                          Approach To
                          Treatment
------------------------------------------------------------------------
EAST TENNESSEE STATE     Asthma and Allergy   09/17/2014       $3,000.00
 UNIVERSITY RESEARCH      2014: What's New,
 FOUNDATION               What's Hot
------------------------------------------------------------------------
AMERICAN COLLEGE OF      2014 ACG             09/17/2014      $25,000.00
 GASTROENTEROLOGY         Presidential
                          Poster Award
------------------------------------------------------------------------
PARTNERS HEALTHCARE      2014 Personalized    09/17/2014      $15,000.00
 SYSTEM INC.              Medicine
                          Conference
------------------------------------------------------------------------
PERSONALIZED MEDICINE    Turning the Tide     09/17/2014       $5,000.00
 COALITION                Against Cancer
                          2014 National
                          Conference
------------------------------------------------------------------------
CEDARS-SINAI MEDICAL     Rheumatology Grand   09/21/2014       $5,000.00
 CENTER                   Rounds 2014
------------------------------------------------------------------------
AMERICAN THYROID         Early Riser          09/21/2014     $125,900.00
 ASSOCIATION              Symposium:
                          Medullary Thyroid
                          Cancer
------------------------------------------------------------------------
SAFETY PHARMACOLOGY      14th Annual Safety   09/21/2014       $3,000.00
 SOCIETY                  Pharmacology
                          Society Annual
                          Meeting
------------------------------------------------------------------------
AMERICAN SOCIETY OF      19th Annual ASHP     09/23/2014      $10,000.00
 HEALTH-SYSTEM            Conference for
 PHARMACISTS              Leaders in Health-
                          System Pharmacy
------------------------------------------------------------------------
AMERICAN ASSOCIATION OF  Scenes and           09/23/2014      $35,000.00
 CLINICAL                 Seminars on
 ENDOCRINOLOGISTS         Hypoglycemia
                          Management:
                          Multidisciplinary
                          Approaches to
                          Improving Safety
                          for Patients with
                          Diabetes
------------------------------------------------------------------------
NATIONAL COMPREHENSIVE   2014 NCCN Congress   09/23/2014      $25,000.00
 CANCER NETWORK, INC.     Series: Utilizing
                          Guidelines to
                          Customize Patient
                          Care in Non-Small
                          Cell Lung Cancer
------------------------------------------------------------------------
CITY OF HOPE NATIONAL    Multidisciplinary    09/25/2014       $3,000.00
 MEDICAL CENTER           Approaches to
                          Cancer Symposium
------------------------------------------------------------------------
THE DEUEL CONFERENCE ON  The 2015 Deuel       09/30/2014      $15,000.00
 LIPIDS                   Conference on
                          Lipids
------------------------------------------------------------------------
AMERICAN COLLEGE OF      2014 ACR/ARHP        09/30/2014      $50,000.00
 RHEUMATOLOGY             Annual Meeting
                          Gout Educational
                          Track
------------------------------------------------------------------------
NORTH AMERICAN SOCIETY   NASPGHAN Research    09/30/2014       $4,000.00
 FOR PEDIATRIC            Skills Workshop
 GASTROENTEROLOGY,
 HEPATOLOGY AND
 NUTRITION
------------------------------------------------------------------------
SOCIETY FOR THE          SITC Workshop on     10/03/2014     $100,000.00
 IMMUNOTHERAPY OF         Combination
 CANCER                   Immunotherapy:
                          Where Do We Go
                          From Here?
------------------------------------------------------------------------
LETTERS and SCIENCES     PARP Inhibition      10/07/2014     $275,478.44
                          for BRCA 1/2
                          Mutation-
                          Associated
                          Cancers and
                          Triple Negative
                          BC Advances in
                          Risk Reduction
                          and Treatment
------------------------------------------------------------------------
CHILDREN'S HOSPITAL      Taking on            10/07/2014       $5,000.00
 CORPORATION              Tomorrow: Global
                          Pediatric
                          Innovation Summit
                          and Awards 2014
------------------------------------------------------------------------
ENZYME MECHANISMS        24th Enzyme          10/07/2014       $3,000.00
 CONFERENCE, INC.         Mechanisms
                          Conference
------------------------------------------------------------------------
NAMI MARYLAND            2014 NAMI Maryland   10/07/2014       $5,000.00
                          Annual Education
                          Conference
------------------------------------------------------------------------
GORDON RESEARCH          Inhibition in the    10/07/2014       $5,000.00
 CONFERENCES              CNS Gordon
                          Research
                          Conference and
                          Seminar
------------------------------------------------------------------------
AMERICAN COLLEGE OF      Cardiometabolic      10/08/2014     $150,000.00
 CARDIOLOGY FOUNDATION    Clinical
                          Community on
                          CardioSource/
                          ACC.org
------------------------------------------------------------------------
NATIONAL ASSOCIATION     Managing Pain in     10/09/2014      $25,000.00
 DIRECTORS OF NURSING     LTC Residents:
 ADMINISTRATION/LTC,      Addressing
 INC.                     Opioiod-Induced
                          Constipation
------------------------------------------------------------------------
AMERICAN HEART           Heart Innovation     10/09/2014      $15,000.00
 ASSOCIATION              Forum
------------------------------------------------------------------------
MEDICAL SOCIETY OF NEW   Medical Society of   10/09/2014       $2,500.00
 JERSEY                   New Jersey 2015
                          Physician
                          Advocacy
                          Conference
------------------------------------------------------------------------
PEDIATRIC ENDOCRINE      PES Parent,          10/13/2014      $50,000.00
 SOCIETY                  Patient and
                          Physician WEB
                          Education Program
                          for Lipodystrophy
                          in Children,
                          Adolescents, and
                          Adults
------------------------------------------------------------------------
TRUSTEES OF THE          7th Focus on Lung    10/13/2014       $3,000.00
 UNIVERSITY OF            Cancer Conference
 PENNSYLVANIA             and 4rd
                          CANPrevent Lung
                          Cancer
------------------------------------------------------------------------
SOCIETY FOR              Merrill J. Egorin    10/13/2014      $10,000.00
 TRANSLATIONAL ONCOLOGY   Workshop in
                          Cancer
                          Therapeutics and
                          Drug Development
------------------------------------------------------------------------
SOCIETY FOR              The Oncologist CME   10/13/2014      $10,000.00
 TRANSLATIONAL ONCOLOGY   Online Journal
                          Curriculum: Lung
                          Cancer
------------------------------------------------------------------------
PERSONALIZED MEDICINE    Integrating          10/15/2014       $5,000.00
 COALITION                Personalized
                          Medicine into
                          Health Care:
                          Solutions Summit
                          2015
------------------------------------------------------------------------
BIOMEDICAL SCIENCE       Hope Scholarship     10/16/2014       $7,500.00
 CAREERS PROGRAM          2015-2016
------------------------------------------------------------------------
AMERICAN COLLEGE OF      Fact vs Fact: The    10/21/2014      $25,000.00
 CARDIOLOGY FOUNDATION    Cholesterol
                          Guidelines Debate
------------------------------------------------------------------------
A. WEBB ROBERTS CENTER   The 41st Annual      10/22/2014       $5,000.00
 OF BAYLOR HEALTH CARE    Williamsburg
 SYSTEM, DALLAS           Conference on
                          Heart Disease
------------------------------------------------------------------------
NATIONAL ASSOCIATION OF  COPD: What NPs in    10/22/2014      $20,000.00
 NURSE PRACTITIONERS IN   Women's Health
 WOMEN'S HEALTH           Need to Know
------------------------------------------------------------------------
SOCIETY FOR THE          SITC 29th Annual     10/22/2014      $10,000.00
 IMMUNOTHERAPY OF         Meeting
 CANCER
------------------------------------------------------------------------
DAIBETES TECHNOLOGY      Diabetes             10/22/2014      $10,000.00
 SOCIETY                  Technology
                          Meeting 2014
------------------------------------------------------------------------
AMERICAN ASSOCIATION OF  2014-2015 AAPS       10/30/2014      $45,000.00
 PHARMACEUTICAL           Sustaining
 SCIENTISTS               Sponsorship
------------------------------------------------------------------------
AMERICAN PSYCHIATRIC     APNA 28th Annual     10/30/2014       $5,000.00
 NURSES ASSOCIATION       Conference-
                          Building
                          Connections: PMH
                          Nursing
                          Perspectives
------------------------------------------------------------------------
PEDIATRIC ENDOCRINE      PES Consensus        10/30/2014      $92,200.00
 SOCIETY                  statement on the
                          Management of
                          Lipodystrophy in
                          Children,
                          Adolescents, and
                          Adults
------------------------------------------------------------------------
LETTERS AND SCIENCES     Ovarian Cancer--     10/30/2014     $287,365.00
                          Evolution and
                          Evidence of
                          Emerging
                          Strategies (ISSS)
------------------------------------------------------------------------
THE CVA MEDICAL          Cardiovascular       11/02/2014       $5,000.00
 EDUCATION FOUNDATION     Update 2015
------------------------------------------------------------------------
UNIVERSITY OF MICHIGAN   Vaccines: Past,      11/04/2014      $10,000.00
                          Present, and
                          Future
------------------------------------------------------------------------
SOCIETY OF TOXICOLOGY    Society of           11/04/2014       $2,000.00
                          Toxicology Annual
                          Meeting
------------------------------------------------------------------------
NATIONAL COMMISSION FOR  CCMEP                11/04/2014      $10,000.00
 THE CERTIFICATION OF     Certification
 CME PROFESSIONALS        Exam for
                          Healthcare CE
                          Professionals
------------------------------------------------------------------------
MEDSTAR WASHINGTON       Cardiovascular       11/05/2014      $50,000.00
 HOSPITAL CENTER          Research
                          Technologies CRT
                          2015
------------------------------------------------------------------------
NATIONAL KIDNEY          Primary Care         11/05/2014      $50,000.00
 FOUNDATION               Practitioner
                          (PCP) Attitudes
                          and Practices:
                          Testing Type-2
                          Diabetic Patients
                          for Chronic
                          Kidney Disease
                          (CKD) Survey
------------------------------------------------------------------------
AMERICAN DIABETES        Pathway To Stop      11/07/2014   $2,500,000.00
 ASSOCIATION              Diabetes
------------------------------------------------------------------------
AMERICAN PHARMACISTS     Optimizing the       11/10/2014      $11,250.00
 ASSOCIATION              Management of
                          Acute Coronary
                          Syndromes through
                          the Transitions
                          of Care
------------------------------------------------------------------------
TEMPLE UNIVERSITY        43rd Annual          11/10/2014       $5,000.00
                          Philadelphia
                          Workshop on
                          Hemostasis,
                          Thrombosis and
                          Atherosclerosis
------------------------------------------------------------------------
NOT-FOR-PROFIT HOSPITAL  Recognizing and      11/11/2014       $3,400.00
 CORPORATION              Treating Acute
                          Coronary Syndrome-
                          Current Guideline
                          Based Management
------------------------------------------------------------------------
CARDIOVASCULAR RESEARCH  Chronic Total        11/11/2014      $10,000.00
 FOUNDATION               Occlusion Summit
                          2015: A Live
                          Demonstration
                          Course
------------------------------------------------------------------------
INTERNATIONAL            IASLC                11/12/2014      $16,000.00
 ASSOCIATION FOR THE      International
 STUDY OF LUNG CANCER     Mentorship
                          Program
------------------------------------------------------------------------
INTERNATIONAL            15th Annual          11/12/2014      $25,000.00
 ASSOCIATION FOR THE      Targeted
 STUDY OF LUNG CANCER     Therapies of Lung
 (IASLC)                  Cancer meeting
------------------------------------------------------------------------
AMERICAN HEART           Scientific           11/13/2014      $30,000.00
 ASSOCIATION, INC.        Sessions 2014
                          Acute Coronary
                          Syndrome Track
------------------------------------------------------------------------
THE JOHNS HOPKINS        The Johns Hopkins    11/13/2014     $138,261.57
 UNIVERSITY               University
                          Allergy and
                          Clinical
                          Immunology
                          Fellowship
                          Program
------------------------------------------------------------------------
REGENTS OF THE           The 2nd Annual       11/16/2014       $5,000.00
 UNIVERSITY OF            UCLA Diabetes
 CALIFORNIA               Symposium
------------------------------------------------------------------------
AMERICAN ASSOCIATION     AACR Annual          11/17/2014      $50,000.00
 FOR CANCER RESEARCH      Meeting--2015
------------------------------------------------------------------------
AMERICAN SOCIETY OF      American Society     11/17/2014      $25,000.00
 HEMATOLOGY               of Hematolgoy
                          Scholar Awards
------------------------------------------------------------------------
AMERICAN SOCIETY OF      The American         11/17/2014      $25,000.00
 HEMATOLOGY               Society of
                          Hematology's
                          Bridge Award
                          Program
------------------------------------------------------------------------
AMERICAN ACADEMY OF      2015 AAAAI Annual    11/18/2014      $30,000.00
 ALLERGY, ASTHMA AND      Meeting Allied
 IMMUNOLOGY (AAAAI)       Health
                          Programming
------------------------------------------------------------------------
AMERICAN PSYCHIATRIC     Psychiatric          11/21/2014      $60,400.00
 NURSES ASSOCIATION       Nursing E Series:
                          Bipolar Disorder
                          Across the
                          Lifespan
------------------------------------------------------------------------
AMERICAN ASSOCIATION OF  New Paradigms in     12/01/2014       $2,500.00
 CLINICAL                 the Practice of
 ENDOCRINOLOGISTS PR      Endocrinology
 CHAPTER
------------------------------------------------------------------------
NATIONAL ASSOCIATION OF  Improving Outcomes   12/01/2014      $25,000.00
 MANAGED CARE             through Evidence-
 PHYSICIANS               Based Diagnosis
                          and Management of
                          Chronic
                          Obstructive
                          Pulmonary Disease
                          (COPD)
------------------------------------------------------------------------
THE GYNECOLOGIC          3rd Semi Annual      12/02/2014      $10,000.00
 ONCOLOGY GROUP           Meeting of NRG
                          ONCOLOGY
                          (Formerly GOG,
                          NSABP, RTOG)
------------------------------------------------------------------------
FLORIDA ALLERGY, ASTHMA  Florida Allergy,     12/02/2014      $10,825.00
 AND IMMUNOLOGY SOCIETY   Asthma and
                          Immunology
                          Society 2015
                          Annual CME
                          Conference
------------------------------------------------------------------------
INTERNATIONAL            16th World           12/02/2014     $200,000.00
 ASSOCIATION FOR THE      Conference on
 STUDY OF LUNG CANCER     Lung Cancer--ISS
 (IASLC)                  Association fee
------------------------------------------------------------------------
NATIONAL ASSOCIATION OF  Evidence-based       12/02/2014      $23,795.71
 SCHOOL NURSES, INC.      asthma care in
                          schools
------------------------------------------------------------------------
THE METHODIST HOSPITAL   Cardiovascular       12/03/2014      $15,000.00
                          Fellows' Bootcamp
                          Laying the
                          Foundation
------------------------------------------------------------------------
NATIONAL COMPREHENSIVE   NCCN 20th Annual     12/03/2014      $85,000.00
 CANCER NETWORK, INC.     Conference
                          General Session:
                          Advancing the
                          Standard of
                          Cancer CareTM
------------------------------------------------------------------------
NATIONAL COMPREHENSIVE   Advances in the      12/03/2014     $100,000.00
 CANCER NETWORK, INC.     Treatment of
                          Ovarian and
                          Cervical Cancers:
                          Expert-
                          Facilitated Small
                          Group Discussions
                          of Challenging
                          Cases
------------------------------------------------------------------------
THE MOUNT SINAI          Complex Coronary     12/03/2014      $10,000.00
 HOSPITAL                 Cases
------------------------------------------------------------------------
JOHNS HOPKINS            The Johns Hopkins    12/03/2014     $150,000.00
 UNIVERSITY               University School
                          of Medicine
                          eDiabetes Review
                          Volume 2
------------------------------------------------------------------------
ROME FOUNDATION          Rome IV: The         12/04/2014     $100,000.00
                          Functional
                          Gastrointestinal
                          Disorders
------------------------------------------------------------------------
UNIVERSITY OF KENTUCKY   9th Platelet         12/04/2014      $10,000.00
 COLLEGE OF MEDICINE      Colloquium
------------------------------------------------------------------------
CONQUER CANCER           2015 Conquer         12/04/2014      $30,000.00
 FOUNDATION OF THE        Cancer Foundation
 AMERICAN SOCIETY OF      of ASCO Merit
 CLINICAL ONCOLOGY        Awards
------------------------------------------------------------------------
CONQUER CANCER           2015 Conquer         12/04/2014      $25,000.00
 FOUNDATION OF THE        Cancer Foundation
 AMERICAN SOCIETY OF      of ASCO
 CLINICAL ONCOLOGY        International
                          Innovation Grant
------------------------------------------------------------------------
NATIONAL COMPREHENSIVE   2015 Annual          12/04/2014      $10,000.00
 CANCER NETWORK NCCN      Nursing Program:
                          Advancing
                          Oncology Nursing
                          at the 20th NCCN
                          Annual Conference
------------------------------------------------------------------------
NATIONAL COMPREHENSIVE   2015 NCCN Oncology   12/04/2014      $10,000.00
 CANCER NETWORK, INC.     Fellows Program:
                          New Horizons in
                          Quality Cancer
                          Care at the 20th
                          Annual Conference
------------------------------------------------------------------------
STENO DIABETES CENTER A/ 28th European        12/04/2014      $20,000.00
 S                        Diabetic
                          Nephropathy Study
                          Group Annual
                          Meeting
------------------------------------------------------------------------
AMERICAN SOCIETY OF      Improving Patient    12/04/2014     $110,000.00
 HEALTH-SYSTEM            Outcomes:
 PHARMACISTS              Maximizing the
                          Role of the GLP-1
                          Based Therapies
                          in Our Patients
                          with Type 2
                          Diabetes
------------------------------------------------------------------------
ENDOCRINE SOCIETY        ENDO 2015 Thyroid    12/04/2014      $55,000.00
                          Sessions
------------------------------------------------------------------------
UNIVERSITY OF TEXAS      XVI Curso            12/07/2014      $10,000.00
 SOUTHWESTERN MEDICAL     Intensivo de
 CENTER                   Diabetes,
                          Endocrinologia y
                          Enfermedades
                          Metabolicas
------------------------------------------------------------------------
AMERICAN ASSOCIATION OF  Advances in          12/07/2014      $10,000.00
 CLINICAL                 Medical and
 ENDOCRINOLOGISTS         Surgical
                          Management of
                          Thyroid Cancer
------------------------------------------------------------------------
AMERICAN PAIN SOCIETY    2015 Fundamentals    12/07/2014      $35,000.00
                          of Pain
                          Management: An
                          Interdisciplinary
                          Primer
------------------------------------------------------------------------
HEMATOLOGY/ONCOLOGY      2015 HOPA 11th       12/07/2014      $25,000.00
 PHARMACY ASSOCIATION     Annual Conference
------------------------------------------------------------------------
LUMEN FOUNDATION         Lumen Global 2015    12/08/2014      $75,000.00
------------------------------------------------------------------------
NATIONAL ASSOCIATION OF  Mentoring Program    12/08/2014      $10,000.00
 NEONATAL NURSES          Toolkit for
                          Novice Nurse
                          Practitioners
------------------------------------------------------------------------
CONQUER CANCER           2015 Conquer         12/08/2014     $250,000.00
 FOUNDATION OF THE        Cancer Foundation
 AMERICAN SOCIETY OF      of ASCO Career
 CLINICAL ONOCLOGY        Development Award
                          (CDA)
------------------------------------------------------------------------
CONQUER CANCER           2015 Conquer         12/08/2014      $10,500.00
 FOUNDATION OF THE        Cancer Foundation
 AMERICAN SOCIETY OF      of ASCO
 CLINICAL ONCOLOGY        International
                          Development and
                          Education Award
                          (IDEA)
------------------------------------------------------------------------
THE ENDOCRINE SOCIETY    Applying the         12/08/2014     $525,980.00
                          Evidence for GLP-
                          1 Receptor
                          Agonists in Type
                          2 Diabetes:
                          Practice
                          Perspectives
------------------------------------------------------------------------
FORCE--FACING OUR RISK   Joining FORCEs       12/08/2014      $50,000.00
 OF CANCER EMPOWERED      Against
                          Hereditary Cancer
                          Conference
------------------------------------------------------------------------
AMERICAN COLLEGE OF      Lipid Management     12/08/2014      $50,000.00
 CARDIOLOGY FOUNDATION    Today: Unanswered
                          Questions and
                          Unquestioned
                          Answers--Live
                          Clinical Focus
                          Session at ACC.15
------------------------------------------------------------------------
AMERICAN PHARMACISTS     Access to Care:      12/09/2014      $11,250.00
 ASSOCIATION              Addressing Health
                          Literacy in
                          Diabetes
------------------------------------------------------------------------
THE ENDOCRINE SOCIETY    Diabetes Diagnosis   12/09/2014      $50,000.00
                          and Management
                          2015
------------------------------------------------------------------------
ENDOCRINE SOCIETY        Endocrine Fellows    12/09/2014      $70,000.00
                          Conference: Type
                          1 Diabetes Care
                          and Management
------------------------------------------------------------------------
CLINICAL AND PATIENT     Clinical Issues in   12/09/2014     $368,966.00
 EDUCATORS ASSOCIATION    Type 2 Diabetes:
                          Discussions and
                          Debates Around
                          GLP-1 Receptor
                          Agonists
------------------------------------------------------------------------
AMERICAN COLLEGE OF      ACCs 64th Annual     12/09/2014     $100,000.00
 CARDIOLOGY FOUNDATION    Scientific
                          Session--ACC.15
                          Acute Coronary
                          Syndromes
                          Clinical Learning
                          Pathway
------------------------------------------------------------------------
CONQUER CANCER           2015 Conquer         12/10/2014      $60,000.00
 FOUNDATION OF THE        Cancer Foundation
 AMERICAN SOCIETY OF      Young
 CLINICAL ONCOLOGY        Investigator
                          Award
------------------------------------------------------------------------
ENDOCRINE SOCIETY        Diabetes Masters     12/10/2014     $235,867.00
                          Series 2015 :
                          Solving the
                          Puzzle: Putting
                          the Pieces
                          Together to
                          Provide Quality
                          T2DM Care
------------------------------------------------------------------------
CONQUER CANCER           2015 ASCO Annual     12/10/2014     $112,000.00
 FOUNDATION OF THE        Meeting Lung
 AMERICAN SOCIETY OF      Cancer Track
 CLINICAL ONCOLOGY
------------------------------------------------------------------------
INSTITUTE FOR MEDICAL    Who s on First?      12/10/2014     $316,029.80
 AND NURSING EDUCATION    What s on Second?
                          Identifying a
                          Line-up of Newer
                          Agents to
                          Individualize
                          Care for Your
                          Patient with T2DM
------------------------------------------------------------------------
PENNSYLVANIA STATE       Controlling Severe   12/11/2014     $236,659.94
 UNIVERSITY               Asthma Today and
                          Tomorrow
------------------------------------------------------------------------
CHILDREN'S HOSPITAL      2015 Weinstein       12/11/2014       $5,000.00
 CORPORATION              Cardiovascular
                          Development
                          Conference
------------------------------------------------------------------------
NATIONAL COMPREHENSIVE   2015-2016 Monthly    12/11/2014      $35,000.00
 CANCER NETWORK, INC      Oncology Tumor
                          Boards: A
                          Multidisciplinary
                          Approach to
                          Individualized
                          Patient Care
------------------------------------------------------------------------
ENDOCRINE SOCIETY        ENDO 2015 Diabetes   12/14/2014      $30,000.00
                          Sessions
------------------------------------------------------------------------
AMERICAN ASSOCIATION OF  Case Challenges in   12/14/2014     $181,705.00
 CLINICAL                 T2D: Applying the
 ENDOCRINOLOGISTS         AACE Algorithm to
                          Practice
------------------------------------------------------------------------
THE CHEST FOUNDATION     The CHEST            12/15/2014     $180,000.00
                          Foundation COPD
                          Research Grant
                          Program
------------------------------------------------------------------------
JOSLIN DIABETES CENTER,  SGLT-2 Inhibitors    12/15/2014     $321,885.00
 INC.                     in Type 2
                          Diabetes:
                          Incorporating New
                          Approaches Into
                          Practice Through
                          an
                          Interdisciplinary
                          Exploration
------------------------------------------------------------------------
AMERICAN OSTEOPATHIC     The Path to Better   12/15/2014     $263,394.54
 ASSOCIATION              T2DM Outcomes, A
                          Coordinated
                          Approach to
                          Patient-centered
                          Care
------------------------------------------------------------------------
UNIVERSITY OF            Optimizing           12/21/2014      $62,825.00
 CINCINNATI               Outcomes in Type
                          2 Diabetes:
                          Integrating
                          Longer Acting GLP-
                          1 Receptor
                          Agonists
------------------------------------------------------------------------
RICHMOND UNIVERSITY      Treatment-           12/22/2014       $1,100.00
 MEDICAL CENTER           Refractory Gout
------------------------------------------------------------------------
DUKE UNIVERSITY SCHOOL   Regional Systems     01/04/2015   $3,500,000.00
 OF MEDICINE              Accelerator:
                          Implementation of
                          The American
                          Heart
                          Associations
                          Mission: Lifeline-
                          AMI Discharge and
                          Follow Up
                          Demonstration
                          Project
------------------------------------------------------------------------
AMERICAN COLLEGE OF      You Say Do, I Say    01/06/2015     $150,000.00
 CARDIOLOGY FOUNDATION    Don t:
                          Controversial
                          Debates in ACS--
                          Live Clinical
                          Focus Session at
                          ACC.15
------------------------------------------------------------------------
AMERICAN COLLEGE OF      ACC.15 Prevention    01/07/2015      $75,000.00
 CARDIOLOGY FOUNDATION    Learning Pathway
------------------------------------------------------------------------
AMERICAN HEART           American Heart       01/08/2015   $2,000,000.00
 ASSOCIATION, INC.        Association
                          Cardiovascular
                          Genome Phenome
                          Study (CV-GPS)
------------------------------------------------------------------------
AMERICAN HEART           American Heart       01/11/2015   $6,000,000.00
 ASSOCIATION, INC.        Association s
                          Guideline
                          Transformation
                          and Optimization
                          (GTO) Program
------------------------------------------------------------------------
CARDIOVASCULAR RESEARCH  Post Conference      01/14/2015     $100,000.00
 FOUNDATION               CME Webcast
                          Series 2015
------------------------------------------------------------------------
GASTROINTESTINAL AND     The 2015 US GI and   01/14/2015      $35,000.00
 LIVER ASSOCIATION OF     Liver Association
 THE AMERICAS (GALA)      of the Americas
                          (GALA) Conference
                          Series
------------------------------------------------------------------------
AMERICAN COLLEGE OF      ACCs 64th Annual     01/14/2015      $25,000.00
 CARDIOLOGY FOUNDATION    Scientific
                          Session (ACC.15)
                          TCT@ACC-i2
                          Learning Pathway
------------------------------------------------------------------------
GORDON RESEARCH          2015 Gordon          01/14/2015       $5,000.00
 CONFERENCES              Research
                          Conference on the
                          Molecular and
                          Cellular Biology
                          of Lipids
------------------------------------------------------------------------
GEORGIA ASSOCIATION OF   Cardiology Track--   01/14/2015       $5,000.00
 PHYSICIAN ASSISTANTS     How PAs Can
                          Impact Patient
                          Outcomes Across
                          Cardiovascular
                          Diseases (Part of
                          GAPA 2015 Spring
                          Conference)
------------------------------------------------------------------------
AMERICAN ASSOCIATION OF  Endocrine            01/15/2015       $5,000.00
 CLINICAL                 University:
 ENDOCRINOLOGISTS         Disease
                          Management and
                          Technology Skills
                          for Fellows-in-
                          Training (Thyroid
                          Module)
------------------------------------------------------------------------
UNIVERSITY OF TEXAS      16th Annual          01/15/2015       $3,000.00
 HEALTH SCIENCE CENTER    Practical
 SAN ANTONIO SCHOOL OF    Applications of
 MEDICINE                 New Agents in
                          Oncology
------------------------------------------------------------------------
NATIONAL LIPID           National Lipid       01/15/2015      $15,000.00
 ASSOCIATION              Association 2015
                          Lipid Academy
------------------------------------------------------------------------
NATIONAL LIPID           2015 Masters in      01/15/2015      $15,000.00
 ASSOCIATION              Lipidology
------------------------------------------------------------------------
EMORY UNIVERSITY         Atlanta Clinical     01/18/2015      $15,000.00
                          Cardiology Update
------------------------------------------------------------------------
SOCIETY FOR              SCAI 2015            01/27/2015      $85,000.00
 CARDIOVASCULAR           Scientific
 ANGIOGRAPHY AND          Sessions
 INTERVENTIONS
------------------------------------------------------------------------
ENDOCRINE SOCIETY        Thyroid Endocrine    01/28/2015      $10,000.00
                          Self-Assessment
                          Program 2015
------------------------------------------------------------------------
SCRIPPS HEALTH           Scripps 35th         01/29/2015       $5,000.00
                          Annual
                          Conference:
                          Clinical
                          Hematology and
                          Oncology 2015
------------------------------------------------------------------------
NORTHEASTERN UNIVERSITY  Boston Symposium     01/29/2015       $2,500.00
                          on Organic and
                          Bioorganic
                          Chemistry (BSOBC)
------------------------------------------------------------------------
CARDIOVASCULAR RESEARCH  ACS/STEMI: Focus     01/29/2015      $60,000.00
 FOUNDATION               on Acute Care at
                          SCAI 2015
------------------------------------------------------------------------
NATIONAL ASSOCIATION OF  Exploring Optimal    01/29/2015      $25,000.00
 MANAGED CARE             Antiplatelet
 PHYSICIANS               Therapies in the
                          Management of
                          Acute Coronary
                          Syndrome (ACS)
------------------------------------------------------------------------
CARDIOVASCULAR RESEARCH  21st Annual          01/29/2015      $25,000.00
 FOUNDATION               Interventional
                          Cardiology
                          Fellows Course
------------------------------------------------------------------------
UNIVERSITY OF FLORIDA    Vascular Biology     01/29/2015      $15,000.00
                          Working Group US
                          Chapter Meeting
------------------------------------------------------------------------
IOWA PHYSICIAN           Update on Lipid      01/29/2015       $6,500.00
 ASSISTANT SOCIETY        Management
------------------------------------------------------------------------
PREVENTIVE               Cardiovascular       02/01/2015      $25,000.00
 CARDIOVASCULAR NURSES    Risk Reduction:
 ASSOCIATION              Leading the Way
                          in Prevention
                          (21st Annual
                          Symposium)
------------------------------------------------------------------------
PRIMARY CARE NETWORK,    Are Gout Goals       02/02/2015     $619,095.00
 INC.                     Achievable? The
                          Provider/ Patient
                          Alliance
------------------------------------------------------------------------
PREVENTIVE               PCNA-Triglycerides   02/02/2015     $179,540.00
 CARDIOVASCULAR NURSES
 ASSOCIATION
------------------------------------------------------------------------
NATIONAL LIPID           National Lipid       02/02/2015     $120,000.00
 ASSOCIATION              Association 2015
                          Scientific
                          Meeting Series
------------------------------------------------------------------------
AMERICAN HEART           Chest Pain           02/02/2015      $15,000.00
 ASSOCIATION              Coordinator Boot
                          Camp
------------------------------------------------------------------------
THE BOARD OF REGENTS OF  Cardiovascular       02/08/2015       $5,000.00
 THE UNIVERSITY OF        Medicine and
 WISCONSIN SYSTEM         Prevention Update
                          for Primary Care
------------------------------------------------------------------------
UNIVERSITY OF KANSAS     6th Expert           02/09/2015       $5,000.00
 MEDICAL CENTER           Strategies in
                          Endoscopy,
                          Gastrointestinal
                          and Liver
                          Disorders
------------------------------------------------------------------------
TRUSTEES OF THE          2nd Cardiovascular   02/11/2015       $5,000.00
 UNIVERSITY OF            Symposium
 PENNSYLVANIA/CME
------------------------------------------------------------------------
AMERICAN PHARMACISTS     APhA2015 Rise in     02/11/2015      $22,500.00
 ASSOCIATION              Oral Oncologic
                          Medications
                          Creates New
                          Challenges in
                          Adherence
------------------------------------------------------------------------
EMORY UNIVERSITY         EPIC SEC Emory       02/11/2015      $25,000.00
                          Practical
                          Intervention
                          Course Southeast
                          Consortium
------------------------------------------------------------------------
NATIONAL COMPREHENSIVE   Advances in the      02/11/2015     $232,693.00
 CANCER NETWORK           Treatment of
                          Ovarian and
                          Cervical Cancers:
                          Expert-
                          Facilitated Small
                          Group Discussions
                          of Challenging
                          Cases
------------------------------------------------------------------------
REGENTS OF THE           Moores Cancer        02/12/2015       $3,000.00
 UNIVERSITY OF            Center 11th
 CALIFORNIA               Industry/Academia
                          Translational
                          Oncology
                          Symposium
------------------------------------------------------------------------
SCRIPPS HEALTH           The Future of        02/12/2015      $10,000.00
                          Genomic Medicine
                          VIII
------------------------------------------------------------------------
DELAWARE ACADEMY OF      Hyperlipidemia       02/12/2015       $2,780.00
 PHYSICIAN ASSISTANTS
------------------------------------------------------------------------
THE MASSACHUSETTS        29th Harvard         02/17/2015       $5,000.00
 GENERAL HOSPITAL         Critical Issues
                          in Tumor
                          Microenvironment:
                          Angiogenesis
                          Metastasis and
                          Immunology Course
------------------------------------------------------------------------
KERN ASPEN LIPID         Emerging Therapies   02/17/2015      $10,000.00
 CONFERENCE               for
                          Cardiovascular
                          Diseases: A
                          Dialogue Between
                          Academic and
                          Pharmaceutical
                          Research
------------------------------------------------------------------------
FLORIDA ASSOCIATION OF   Acute Coronary       02/17/2015       $8,325.00
 CONSULTANT PHARMACISTS   Syndrome;
                          Strategies to
                          Optimize
                          Transitions in
                          Care and Reduce
                          Readmissions
------------------------------------------------------------------------
ST. JOSEPH'S REGIONAL    COPD                 02/18/2015       $1,900.00
 MEDICAL CENTER
------------------------------------------------------------------------
CARDIOVASCULAR RESEARCH  Issues with DAPT     02/18/2015      $50,000.00
 FOUNDATION               Series 2015
------------------------------------------------------------------------
NURSE PRACTITIONER       The Challenges of    02/19/2015       $5,000.00
 ASSOCIATES FOR           Asthma and COPD
 CONTINUING EDUCATION     in Primary Care
 (NPACE)
------------------------------------------------------------------------
NORTHWESTERN UNIVERSITY  The 8th Annual       02/19/2015       $2,500.00
                          Womens
                          Cardiovascular
                          Health Symposium
------------------------------------------------------------------------
AMERICAN HEART           Atlanta Mission:     02/19/2015       $2,500.00
 ASSOCIATION              Lifeline Meeting
------------------------------------------------------------------------
AMERICAN ASSOCIATION OF  How to Talk to       02/22/2015     $231,590.00
 NURSE PRACTITIONERS      Your Patients
                          about Opioid-
                          induced
                          Constipation: A
                          Dialogue about
                          New Advances
------------------------------------------------------------------------
AMERICAN THYROID         American Thyroid     02/22/2015      $25,000.00
 ASSOCIATION              Association
                          Satellite
                          Symposium: ATA
                          Guidelines on
                          Medullary Thyroid
                          Cancer and
                          Pediatric Thyroid
                          Cancer
                          Highlights,
                          Controversies a
------------------------------------------------------------------------
THOMAS JEFFERSON         3rd Annual           02/22/2015       $3,000.00
 UNIVERSITY               Jefferson Lung
                          Cancer Symposium
                          2015
------------------------------------------------------------------------
AMERICAN COLLEGE OF      What's New in        02/22/2015      $95,085.00
 CHEST PHYSICIANS         Asthma/COPD
                          Syndrome
------------------------------------------------------------------------
WEST PENN ALLEGHENY      Cardiovascular       02/22/2015      $10,000.00
 HEALTH SYSTEM            Medicine Update
                          2015
------------------------------------------------------------------------
AMERICAN DIABETES        62nd Annual          02/23/2015      $10,000.00
 ASSOCIATION              Advanced
                          Postgraduate
                          Course 2015
------------------------------------------------------------------------
SOCIETY OF GYNECOLOGIC   SGO Annual Meeting   02/23/2015      $50,000.00
 ONCOLOGY                 on Women's Cancer
------------------------------------------------------------------------
BAYLOR UNIVERSITY        The 18th Annual      02/23/2015       $3,000.00
 MEDICAL CENTER DBA A.    Tyler Breast
 WEBB ROBERTS CENTER      Cancer Conferecne
                          2015
------------------------------------------------------------------------
PENNSYLVANIA ACADEMY OF  PAFP/F Live and      02/23/2015       $5,000.00
 FAMILY PHYSICIANS        Enduring CME
 FOUNDATION               Primary and
                          Secondary
                          Prevention of
                          ASCVD
------------------------------------------------------------------------
ONCOLOGY NURSING         Oncology Nursing     02/23/2015      $25,000.00
 SOCIETY                  Society 40th
                          Annual Congress
------------------------------------------------------------------------
AMERICAN ASSOCIATION OF  2015-2016 AAPS       02/23/2015      $50,000.00
 PHARMACEUTICAL           Sustaining
 SCIENTISTS               Sponsorship
------------------------------------------------------------------------
ASPEN LUNG CONFERENCE    Thomas L. Petty      02/24/2015      $15,000.00
                          Aspen Lung
                          Conference:Asthma
                          2015: Mechanisms
                          to Personalized
                          Medicine
------------------------------------------------------------------------
ST. FRANCIS HOSPITAL--   Intravascular        02/26/2015       $7,000.00
 U.S. CATHOLIC            Coronary Imaging
 CONFERENCE               and Physiology
                          2015: A Clinical
                          Workshop
------------------------------------------------------------------------
NATIONAL ASSOCIATION OF  NAPNAP Conference    02/26/2015       $7,500.00
 PEDIATRIC NURSE          Sponsorship
 PRACTITIONERS
------------------------------------------------------------------------
AMERICAN ASSOCIATION     95th Annual          02/26/2015      $10,000.00
 FOR THORACIC SURGERY     Meeting American
                          Association for
                          Thoracic Surgery
------------------------------------------------------------------------
NATIONAL KIDNEY          Session Support:     02/26/2015      $20,000.00
 FOUNDATION INC.          CKD MANAGEMENT
                          ALONG THE
                          CONTINUUM: FROM
                          PREDIALYSIS TO
                          POLICY
------------------------------------------------------------------------
CITY OF HOPE NATIONAL    15th Annual          03/01/2015       $5,000.00
 MEDICAL CENTER           Rachmiel Levine
                          Diabetes and
                          Obesity Symposium
------------------------------------------------------------------------
AMERICAN THORACIC        ATS 2015             03/01/2015      $25,000.00
 SOCIETY                  International
                          Conference,
                          Fellows Track
                          Symposium
------------------------------------------------------------------------
AMERICAN THORACIC        2015 International   03/01/2015      $10,000.00
 SOCIETY ATS              Conference--Selec
                          ted Topics in
                          Asthma
------------------------------------------------------------------------
NATIONAL JEWISH HEALTH   Improving the        03/01/2015      $10,000.00
                          Quality of Care
                          for Patients with
                          Asthma
------------------------------------------------------------------------
ST. JOSEPH'S REGIONAL    Year in Review in    03/01/2015       $3,700.00
 MEDICAL CENTER           Acute Coronary
                          Syndromes
------------------------------------------------------------------------
THE BOARD OF REGENTS OF  COPD9USA             03/02/2015      $40,000.00
 THE UNIVERSITY OF
 NEBRASKA DBA THE
 UNIVERSITY OF NEBRASKA
 MEDICAL CENTER
------------------------------------------------------------------------
AMERICAN THORACIC        ATS 2015             03/02/2015      $72,919.82
 SOCIETY                  International
                          Conference--Selec
                          ted Topics in
                          COPD
------------------------------------------------------------------------
NATIONAL JEWISH HEALTH   Best Practices in    03/02/2015      $72,161.00
                          Managing Patients
                          with COPD:
                          Emerging
                          Therapies and
                          Patient Education
                          Strategies
------------------------------------------------------------------------
CARDIOVASCULAR RESEARCH  DAPT Dilemmas: A     03/02/2015      $69,100.00
 FOUNDATION               Case-Based
                          Roundtable
                          Tutorial
------------------------------------------------------------------------
ALZHEIMER'S ASSOCIATION  2015 Alzheimers      03/02/2015      $50,000.00
                          Association
                          Research
                          Roundtable
------------------------------------------------------------------------
CONQUER CANCER           2015 ASCO Annual     03/02/2015      $56,000.00
 FOUNDATION OF THE        Meeting
 AMERICAN SOCIETY OF      Gynecologic
 CLINICAL ONCOLOGY        Cancer Track:
                          Scientific and
                          Educational
                          Program
------------------------------------------------------------------------
AMERICAN ACADEMY OF      AAPA Conference      03/02/2015       $5,000.00
 PHYSICIAN ASSISTANTS     2015--CardiologyT
                          rack
------------------------------------------------------------------------
PREVENTIVE               The Post-ACS         03/04/2015     $100,000.00
 CARDIOVASCULAR NURSES    Patient:
 ASSOCIATION              Adherence to
                          Critical
                          Therapies in the
                          Short- and Long-
                          Term
------------------------------------------------------------------------
NATIONAL ASSOCIATION OF  2015 Charitable      03/04/2015      $30,000.00
 FREE AND CHARITABLE      Health Care
 CLINICS                  Education and
                          Training
                          Symposium
------------------------------------------------------------------------
GORDON RESEARCH          High Throughput      03/04/2015       $2,500.00
 CONFERENCES              Chemistry and
                          Chemical Biology
------------------------------------------------------------------------
NEW YORK ACADEMY OF      Non-Motor            03/04/2015       $2,000.00
 SCIENCES                 Symptoms:
                          Unraveling the
                          ``Invisible''
                          Face of Parkinson
                          s Disease
------------------------------------------------------------------------
SOCIETY FOR PHYSICIAN    SPAP's 9th Annual    03/08/2015       $1,500.00
 ASSISTANTS IN            Conference
 PEDIATRICS
------------------------------------------------------------------------
JDRF INTERNATIONAL       TypeOneNation        03/08/2015       $4,500.00
                          Research Summit
------------------------------------------------------------------------
GORDON RESEARCH          Solving Knowledge    03/08/2015       $3,000.00
 CONFERENCE               Gaps in Drug
                          Metabolism and
                          Pharmacokinetic
                          Prediction,
                          Improving
                          Translational
                          Medicine
------------------------------------------------------------------------
NURSE PRACTITIONER       Clinical Pearls in   03/09/2015       $2,500.00
 ASSOCIATES FOR           Managing Diabetes
 CONTINUING EDUCATION     in 2015
 (NPACE)
------------------------------------------------------------------------
PRESIDENT AND FELLOWS    Cardiovascular       03/09/2015      $11,500.00
 OF HARVARD COLLEGE       Medicine 2015:
                          Updates for the
                          Practitioner
------------------------------------------------------------------------
AMERICAN ASSOCIATION OF  Diabetes Sessions    03/10/2015      $25,000.00
 CLINICAL                 at Endocrine
 ENDOCRINOLOGISTS         University:
                          Disease
                          Management and
                          Technology Skills
                          for Endocrinology
                          Fellows in
                          Training
------------------------------------------------------------------------
NEBRASKA ACADEMY OF      Gout 2015            03/10/2015       $1,500.00
 PHYSICIAN ASSISTANTS
------------------------------------------------------------------------
NATIONAL COMPREHENSIVE   NCCN 2015 Oncology   03/10/2015      $20,000.00
 CANCER NETWORK, INC.     Case Manager and
                          Medical Director
                          Program
------------------------------------------------------------------------
GORDON RESEARCH          Preclinical Form     03/11/2015         $500.00
 CONFERENCES              and Formulation
                          for Drug
                          Discovery GRC/GRS
------------------------------------------------------------------------
AMERICAN ASSOCIATION     AACR Annual          03/12/2015      $25,000.00
 FOR CANCER RESEARCH      Meeting--2015
------------------------------------------------------------------------
THE HOPE FOUNDATION      2015 SWOG Group      03/12/2015       $5,000.00
                          Meetings
------------------------------------------------------------------------
AMERICAN HEAD AND NECK   American Head and    03/12/2015      $10,000.00
 SOCIETY                  Neck Society 2015
                          Annual Meeting
------------------------------------------------------------------------
BOSTON CHILDREN'S        Pediatric Asthma     03/16/2015       $3,000.00
 HOSPITAL                 and Allergy
                          Updates for
                          Primary Care
                          Providers
------------------------------------------------------------------------
NURSE PRACTITIONER       Managing Asthma      03/16/2015       $1,500.00
 ASSOCIATES FOR           and COPD in 2015
 CONTINUING EDUCATION
 (NPACE)
------------------------------------------------------------------------
HEALTHCARE ALLIANCE FOR  Essentials in        03/16/2015       $8,400.00
 MEDICAL EDUCATION        Primary Care
------------------------------------------------------------------------
WEST VIRGINIA ACADEMY    Opioid Induced       03/17/2015       $3,000.00
 OF FAMILY PHYSICIANS     Constipation
------------------------------------------------------------------------
ECOG RESEARCH AND        2015 ECOG-ACRIN      03/18/2015       $5,000.00
 EDUCATION FOUNDATION,    Spring Group
 INC.                     Meeting
------------------------------------------------------------------------
CONQUER CANCER           2015 ASCO Annual     03/18/2015      $84,000.00
 FOUNDATION OF THE        Meeting Breast
 AMERICAN SOCIETY OF      Cancer Track:
 CLINICAL ONCOLOGY        Scientific and
                          Educational
                          Program
------------------------------------------------------------------------
AMERICAN COLLEGE OF      Diabetes is          03/19/2015      $15,000.00
 OSTEOPATHIC FAMILY       Primary
 PHYSICIANS               Addressing
                          Primary Care
                          Clinical Gaps in
                          Diabetes
                          Management by
                          Partnering With
                          Experts
------------------------------------------------------------------------
MERCY HEALTH SYSTEM      Care Transitions     03/19/2015       $5,000.00
 SEPA                     Conference
------------------------------------------------------------------------
THE MEDICAL UNIVERSITY   10th Annual          03/19/2015       $5,000.00
 OF SOUTH CAROLINA        Symposium
                          entitled the
                          Nephrology Update
                          for Primary Care
                          and Hospital
                          Medicine
------------------------------------------------------------------------
ALZHEIMER'S ASSOCIATION  2015 Alzheimer's     03/23/2015      $95,000.00
                          Association
                          International
                          Conference
------------------------------------------------------------------------
SOCIETY FOR              2015 Annual          03/23/2015      $25,000.00
 TRANSLATIONAL ONCOLOGY   Meeting
------------------------------------------------------------------------
SWEDISH MEDICAL CENTER   Thyroid Cancer and   03/24/2015       $3,000.00
 FOUNDATION               Parathyroid
                          Disease--A
                          Practical
                          Approach
------------------------------------------------------------------------
ASSOCIATION OF WOMEN'S   AWHONN Annual        03/24/2015       $7,500.00
 HEALTH, OBSTETRIC AND    Convention
 NEONATAL NURSES
 (AWHONN)
------------------------------------------------------------------------
GORDON RESEARCH          2015 Proteins        03/24/2015       $3,000.00
 CONFERENCES              Gordon Conference
------------------------------------------------------------------------
AMERICAN ASSOCIATION OF  AACE 24th Annual     03/25/2015      $30,000.00
 CLINICAL                 Scientifc and
 ENDOCRINOLOGISTS         Clinical Congress
                          (Diabetes
                          portion)
------------------------------------------------------------------------
THE ASSOCIATION FOR      AFTD's Annual        03/25/2015       $1,000.00
 FRONTOTEMPORAL           Education
 DEGENERATION (AFTD)      Conference
------------------------------------------------------------------------
TRINITAS REGIONAL        Lung Cancer          03/25/2015       $1,750.00
 MEDICAL CENTER
------------------------------------------------------------------------
INSTITUTE FOR PATIENT    2015 Premature       03/25/2015     $125,000.00
 ACCESS                   Infant Health
                          Summit
------------------------------------------------------------------------
SOCIETY FOR              Young Investigator   03/25/2015      $25,000.00
 NEUROSCIENCE             Award
------------------------------------------------------------------------
ST. DOMINIC--JACKSON     STOP STEMI and       03/25/2015      $25,000.00
 MEMORIAL HOSPITAL        STOP STROKE
                          program by
                          Pulsara
------------------------------------------------------------------------
AMERICAN ASSOCIATION     Anti-cancer Drug     03/26/2015      $10,000.00
 FOR CANCER RESEARCH      Action and Drug
                          Resistance:
------------------------------------------------------------------------
YALE UNIVERSITY          2015 New England     03/26/2015       $3,000.00
                          Thyroid Club
                          Program
------------------------------------------------------------------------
AMERICAN ASSOCIATION OF  AACE 24th Annual     03/26/2015      $25,000.00
 CLINICAL                 Scientific and
 ENDOCRINOLOGISTS         Clinical Congress
                          (Thyroid
                          sessions)
------------------------------------------------------------------------
CLEVELAND CLINIC         Cleveland Breast     03/26/2015       $5,000.00
 EDUCATIONAL FOUNDATION   Cancer 2015:
                          Collaborating For
                          A Cure
------------------------------------------------------------------------
OKLAHOMA HEART RESEARCH  26th Annual Update   03/26/2015       $2,500.00
 AND EDUCATION            in Cardiology
 FOUNDATION
------------------------------------------------------------------------
CEDARS-SINAI MEDICAL     3rd Annual           03/29/2015       $5,000.00
 CENTER                   Experimental
                          Therapeutics in
                          Oncology: The
                          Road to
                          Personalized
                          Medicine
------------------------------------------------------------------------
CASE MANAGEMENT SOCIETY  CMSA 2015            03/29/2015      $15,000.00
 OF AMERICA               Conference and
                          Expo
------------------------------------------------------------------------
SOCIETY FOR              SCAI Complex         03/29/2015      $15,000.00
 CARDIOVASCULAR           Peripheral
 ANGIOGRAPHY AND          Vascular
 INTERVENTIONS            Interventions
 FOUNDATION               Course
------------------------------------------------------------------------
AMERICAN COLLEGE OF      Bringing Science     03/29/2015      $50,000.00
 CARDIOLOGY FOUNDATION    to Clinical
                          Practice: Best of
                          ACC 2015
------------------------------------------------------------------------
ICAHN SCHOOL OF          Live Symposium of    03/29/2015      $10,000.00
 MEDICINE AT MOUNT        Complex Coronary
 SINAI                    Valvular and
                          Vascular Cases
------------------------------------------------------------------------
ASOCIACION               Metabolic Syndrome   03/30/2015       $1,500.00
 PUERTORRIQUENA DE        Update:
 GRADUADOS DE             Challenges in
 UNIVERSIDADES            Preventive
 ESPANOLAS-APGUE          Medicine
------------------------------------------------------------------------
UNIVERSITY OF            Breast Symposium     03/30/2015       $3,250.00
 PITTSBURGH               2015: Updates in
                          the Management of
                          Breast Cancer/
                          Breast Disease
------------------------------------------------------------------------
JOHNS HOPKINS            6th Annual Johns     03/30/2015       $2,500.00
 UNIVERSITY               Hopkins
                          Cardiovascular
                          Research Retreat
------------------------------------------------------------------------
SOCIETY FOR VASCULAR     Society for          03/30/2015       $5,000.00
 MEDICINE                 Vascular Medicine
                          26th Annual
                          Scientific
                          Sessions
------------------------------------------------------------------------
NURSE PRACTITIONER       Updates in COPD      03/30/2015       $3,200.00
 ASSOCIATES FOR           2015
 CONTINUING EDUCATION
 (NPACE)
------------------------------------------------------------------------
THE CHRIST HOSPITAL      The FETCH            03/31/2015       $5,000.00
                          Conference
------------------------------------------------------------------------
THE CHEST FOUNDATION     The CHEST            03/31/2015      $30,000.00
                          Foundation Lung
                          Cancer Clinical
                          Research Grant
                          Program
------------------------------------------------------------------------
NEW YORK MEDICAL         Systemic Treatment   03/31/2015       $2,500.00
 COLLEGE                  of Lung Cancer
------------------------------------------------------------------------
THE CENTER OF            8th Annual           03/31/2015       $5,000.00
 EXCELLENCE IN            Cardiovascular
 EDUCATION                Update- A
                          Practical
                          Tutorial
------------------------------------------------------------------------
ST. JOSEPH'S HOSPITAL    4th Annual Arizona   04/01/2015      $15,000.00
 AND MEDICAL CENTER       Diabetes Series:
                          Focus on
                          Treatment
                          Advances, Patient-
                          Centered Care,
                          Obesity and Other
                          Comorbidities
------------------------------------------------------------------------
THE UNIVERSITY OF TEXAS  Annual Meeting of    04/01/2015       $5,000.00
 MD ANDERSON CANCER       the Felix
 CENTER                   Rutledge Society
------------------------------------------------------------------------
GOUT AND URIC ACID       Gout and Uric Acid   04/01/2015      $70,000.00
 EDUCATION SOCIETY        Education Society
                          Roundtable:
                          Elevating the
                          Severity of Gout
                          and Improving
                          Access to Public
                          Education and
                          Treatment
------------------------------------------------------------------------
VIVA PHYSICIANS          VIVA 15: Vascular    04/01/2015      $20,000.00
                          InterVentional
                          Advances
------------------------------------------------------------------------
UNIVERSITY OF            University of        04/02/2015      $20,000.00
 WASHINGTON               Washington
                          Allergy and
                          Immunology
                          Fellowship
------------------------------------------------------------------------
WASHINGTON ACADEMY OF    26th Annual          04/06/2015       $1,500.00
 PHYSICIAN ASSISTANTS     Recertification
                          Review Course and
                          Spring Conference
------------------------------------------------------------------------
CLEVELAND CLINIC         Advances in Lung     04/07/2015       $5,000.00
 EDUCATIONAL FOUNDATION   Cancer: A
                          Multidisciplinary
                          Approach
------------------------------------------------------------------------
FEDERATION OF AMERICAN   Molecular,           04/08/2015      $10,000.00
 SOCIETIES FOR            Structural and
 EXPERIMENTAL BIOLOGY     Clinical Aspects
                          of VK and VK-
                          Dependent
                          Proteins
------------------------------------------------------------------------
FEDERATION OF AMERICAN   FASEB conference     04/08/2015       $5,000.00
 SOCIETIES FOR            on Genetic
 EXPERIMENTAL BIOLOGY     Recombination and
                          Genome
                          Rearrangements
------------------------------------------------------------------------
SCRIPPS WHITTIER         Emerging             04/09/2015      $30,000.00
 DIABETES INSTITUTE       Therapeutic
                          Trends to
                          Optimize Diabetes
                          Care
------------------------------------------------------------------------
AMERICAN COLLEGE OF      2015                 04/09/2015       $5,000.00
 CARDIOLOGY FOUNDATION    Interventional
                          Cardiology Board
                          Preparatory
                          Course
------------------------------------------------------------------------
AMERICAN FEDERATION FOR  2015 Eastern         04/12/2015       $2,500.00
 MEDICAL RESEARCH         Regional Meeting
                          of the American
                          Federation for
                          Medical Research
------------------------------------------------------------------------
PONCE MEDICAL SCHOOL     Overcoming           04/12/2015      $10,000.00
 FOUNDATION INC.          Obstacles to
                          Reduce Acute
                          Coronary Syndrome
------------------------------------------------------------------------
SOUTH CAROLINA ASTHMA    Midlands Regional    04/12/2015       $3,000.00
 ALLIANCE                 Asthma Conference
------------------------------------------------------------------------
PHARMACY QUALITY         Measuring What       04/13/2015      $12,500.00
 ALLIANCE (PQA, INC.)     Matters:
                          Improving Care
                          and Driving the
                          Next Generation
                          of Performance
                          Measures
------------------------------------------------------------------------
METABOLIC ENDOCRINE      The Comprehensive    04/13/2015     $283,155.00
 EDUCATION FOUNDATION     Management of DM--
                          Focus on SGLT2
                          Inhibitors and
                          Combination
                          Therapy--Emerging
                          Concepts of Renal
                          Effects
------------------------------------------------------------------------
ASTHMA AND ALLERGY       Wheezin', Sneezin'   04/14/2015       $5,000.00
 FOUNDATION OF AMERICA,   and Itchin' in
 ALASKA CHAPTER           Alaska
------------------------------------------------------------------------
NATIONAL ASSOCIATION OF  Individualizing      04/14/2015      $25,000.00
 MANAGED CARE             Treatment
 PHYSICIANS, INC.         Strategies to
                          Improve Patient
                          Outcomes in the
                          Management of
                          Type 2 Diabetes
                          (T2DM)
------------------------------------------------------------------------
MIDMICHIGAN MEDICAL      Valley Diabetes      04/15/2015       $2,500.00
 CENTER--MIDLAND          Symposium
------------------------------------------------------------------------
TRUSTEES OF BOSTON       Opioid Induced       04/15/2015     $117,200.00
 UNIVERSITY DBA BOSTON    Constipation: A
 UNIVERSITY SCHOOL OF     Neglected
 MEDICINE                 Complication
------------------------------------------------------------------------
PARTNERS HEALTHCARE      World Medical        04/15/2015      $50,000.00
 SYSTEM                   Innovation Forum
------------------------------------------------------------------------
MASSACHUSETTS INSTITUTE  CANCER COMPLEXITY:   04/15/2015       $5,000.00
 OF TECHNOLOGY            Heterogeneity in
                          Tumor Progression
                          and Drug Response
------------------------------------------------------------------------
AMERICAN SOCIETY OF      ASN Kidney Week--    04/16/2015      $55,000.00
 NEPHROLOGY               CKD Learning
                          Pathway Support
------------------------------------------------------------------------
NATIONAL ASSOCIATION     Leading Care         04/19/2015      $15,000.00
 FOR HEALTHCARE QUALITY   Transitions:
                          Improving Quality
                          in Safety Across
                          the Healthcare
                          Continuum
------------------------------------------------------------------------
FEDERATION OF AMERICAN   12th FASEB Summer    04/19/2015       $7,000.00
 SOCIETIES FOR            Research
 EXPERIMENTAL BIOLOGY     Conference on
                          ``Proteases in
                          Hemostasis and
                          Vascular
                          Biology''
------------------------------------------------------------------------
AMERICAN SOCIETY FOR     ASPMN 25th           04/20/2015      $20,000.00
 PAIN MANAGEMENT          National
 NURSING                  Conference
------------------------------------------------------------------------
REGENTS OF THE           5th International    04/20/2015       $3,000.00
 UNIVERSITY OF            Symposium on Lung-
 CALIFORNIA               Sparing Therapies
                          for Malignant
                          Pleural
                          Mesothelioma
------------------------------------------------------------------------
GORDON RESEARCH          2015 Medicinal       04/20/2015       $3,000.00
 CONFERENCES              Chemistry Gordon
                          Research
                          Conference
------------------------------------------------------------------------
AMERICAN THORACIC        ATS 2015             04/21/2015      $50,000.00
 SOCIETY                  International
                          Conference--Selec
                          ted Topics in
                          Lung Cancer
------------------------------------------------------------------------
OKLAHOMA UNIVERSITY      18th Annual          04/21/2015       $1,500.00
 HEALTH SCIENCES CENTER   Primary Care
                          Update 2015
                          Asthma
------------------------------------------------------------------------
OKLAHOMA UNIVERSITY      18th Annual          04/21/2015       $1,500.00
 HEALTH SCIENCE CENTER    Primary Care
 COLLEGE OF MEDICINE      Update 2015-
                          Ovarian Cancer
------------------------------------------------------------------------
REGENTS OF THE           LIPID MAPS           04/21/2015       $7,500.00
 UNIVERSITY OF            Meeting:
 CALIFORNIA               Lipidomics Impact
                          on Cancer,
                          Metabolic and
                          Inflammatory
                          Diseases
------------------------------------------------------------------------
CARDIOVASCULAR RESEARCH  Knights of the       04/21/2015      $50,000.00
 FOUNDATION               Roundtable 2015:
                          Challenging AMI
                          Therapies
------------------------------------------------------------------------
HOUSTON METHODIST        Cardiovascular       04/21/2015      $15,000.00
 HOSPITAL                 Fellows' Bootcamp-
                          Laying the
                          Foundation
------------------------------------------------------------------------
UNIVERSITY OF            Seventh Annual       04/22/2015       $3,250.00
 PITTSBURGH               Multidisciplinary
                          Thyroid Cancer
                          Symposium:
                          Integrating the
                          New ATA
                          Guidelines into
                          Clinical Practice
------------------------------------------------------------------------
AMERICAN ASSOCIATION OF  36th Annual          04/22/2015       $3,000.00
 ENDOCRINE SURGEONS       Meeting of the
                          American
                          Association of
                          Endocrine
                          Surgeons
------------------------------------------------------------------------
DUKE UNIVERSITY HEALTH   Closing the Gap on   04/22/2015      $20,000.00
 SYSTEM                   Medication
                          Management,
                          Discharge
                          Preparedness and
                          Readmissions
------------------------------------------------------------------------
CLEVELAND CLINIC         ASCO Review          04/23/2015       $3,000.00
 EDUCATIONAL FOUNDATION
------------------------------------------------------------------------
SWEDISH MEDICAL CENTER   Annual Oncology      04/23/2015       $3,000.00
 FOUNDATION               Symposium:
                          Personalized
                          Medicine--Genetic
                          Testing, Targeted
                          Molecular Therapy
                          and WHole Patient
                          Care
------------------------------------------------------------------------
OKLAHOMA UNIVERSITY      18th Annual          04/23/2015       $1,500.00
 HEALTH SCIENCE CENTER    Primary Care
 COLLEGE OF MEDICINE      Update: COPD
------------------------------------------------------------------------
WASHINGTON UNIVERSITY    Update on            04/23/2015       $4,000.00
                          Gynecologic
                          Cancer
------------------------------------------------------------------------
WASHINGTON UNIVERSITY    Cardiology Update    04/23/2015       $4,000.00
 SCHOOL OF MEDICINE,
 ST. LOUIS
------------------------------------------------------------------------
NEW YORK ACADEMY OF      Emerging             04/27/2015       $5,000.00
 SCIENCES                 Approaches to
                          Cancer
                          Immunotherapy
------------------------------------------------------------------------
LYMPHOMA RESEARCH        Lymphoma Research    04/27/2015      $15,000.00
 FOUNDATION               Foundation Immune
                          Checkpoint
                          Inhibitor
                          Workshop
------------------------------------------------------------------------
YALE UNIVERSITY          Yale Cancer Center   04/28/2015       $5,000.00
                          Oncology Series--
                          2015
------------------------------------------------------------------------
MOUNT CARMEL HEALTH      2015 ASCO REVIEW     04/28/2015       $3,000.00
 SYSTEM
------------------------------------------------------------------------
COLUMBIA UNIVERSITY      Breast Cancer        04/28/2015       $3,000.00
 DEPARTMENT OF SURGERY    Management 2015
------------------------------------------------------------------------
NORTHWESTERN UNIVERSITY  4th Annual Chicago   04/28/2015       $6,000.00
                          Cardiovascular
                          Update
------------------------------------------------------------------------
DIGNITY HEALTH ST.       17th Annual          04/29/2015       $6,000.00
 BERNARDINE MEDICAL       Cardiac
 CENTER                   Symposium:
                          Advances in
                          Cardiovascular
                          Disease 2015
------------------------------------------------------------------------
GORDON RESEARCH          2015 Gordon          04/29/2015       $2,500.00
 CONFERENCES              Conference on
                          Heterocyclic
                          Compounds
------------------------------------------------------------------------
INTERNATIONAL SOCIETY    Regulatory and       04/29/2015       $2,500.00
 FOR COMPUTATIONAL        Systems Genomics,
 BIOLOGY INC.             with DREAM
                          Challenges
                          Conference
------------------------------------------------------------------------
YALE UNIVERSITY          Yale ASCO Review     04/30/2015       $3,000.00
                          2015
------------------------------------------------------------------------
UNIVERSITY OF VERMONT    OBESITY AND          04/30/2015       $5,000.00
 AND STATE AGRICULTURAL   METABOLISM: An
 COLLEGE                  Emerging Frontier
                          in Lung Health
                          and Disease
------------------------------------------------------------------------
SWEDISH MEDICAL CENTER   The Transradial      04/30/2015       $5,000.00
 FOUNDATION               Approach: A Case-
                          based and Hands-
                          on Training
                          Course
------------------------------------------------------------------------
MONTEFIORE MEDICAL       Achieving Balance:   05/03/2015     $161,500.00
 CENTER                   Practical
                          Management
                          Strategies for
                          Opioid-Induced
                          Constipation
------------------------------------------------------------------------
CALIFORNIA SOCIETY OF    CSAAI 23rd Annual    05/05/2015       $3,000.00
 ALLERGY, ASTHMA, AND     Educational
 IMMUNOLOGY               Meeting
------------------------------------------------------------------------
TRUSTEES OF THE          Advanced Thyroid     05/06/2015       $5,000.00
 UNIVERSITY OF            Master Class
 PENNSYLVANIA
------------------------------------------------------------------------
CANCER MOLECULAR         Molecular            05/06/2015       $5,000.00
 THERAPEUTICS RESEARCH    Therapeutics of
 ASSOCIATION              Cancer
                          Conference, 2015
------------------------------------------------------------------------
NORTH SHORE LONG ISLAND  Post American        05/07/2015       $3,000.00
 JEWISH HEALTH SYSTEM     Society of
 INC.                     Clinical Oncology
                          2015
------------------------------------------------------------------------
AMERICAN COLLEGE OF      Update in Allergy,   05/12/2015       $5,000.00
 ALLERGY, ASTHMA AND      Asthma and
 IMMUNOLOGY               Immunology
------------------------------------------------------------------------
ALBERT EINSTEIN          Complex              05/14/2015       $5,000.00
 HEALTHCARE NETWORK       Angioplasty
                          Symposium
                          Exchange
                          Philadelphia
------------------------------------------------------------------------
SOCIETY FOR              The Oncologist CME   05/17/2015      $10,000.00
 TRANSLATIONAL ONCOLOGY   Online Journal
                          Curriculum:
                          Breast Cancer
------------------------------------------------------------------------
ANENBERG CENTER FOR      PosterPerspectives   05/18/2015      $25,000.00
 HEALTH SCIENCES AT       : Research
 EISENHOWER               Developments in
                          NSCLC / 2015 ASCO
------------------------------------------------------------------------
WESTERN ASSOCIATION      Hitting the          05/18/2015      $12,500.00
 GYNECOLOGIOC             targets in
 ONCOLOGISTS              Gynecologic
                          Cancer
------------------------------------------------------------------------
AMERICAN THYROID         ATA Early Riser      05/19/2015     $129,500.00
 ASSOCIATION              Symposium: New
                          Modalities to
                          Treat Medullary
                          Thyroid Cancer
------------------------------------------------------------------------
CARDIOVASCULAR RESEARCH  Issues with DAPT:    05/19/2015      $25,000.00
 FOUNDATION               A Case-based
                          Roundtable with
                          the Experts
------------------------------------------------------------------------
LAHEY CLINIC HOSPITAL,   Cardiovascular       05/19/2015       $6,000.00
 INC.                     Disease State of
                          the Art 2015
------------------------------------------------------------------------
AMERICAN COLLEGE OF      ACC Cardiovascular   05/19/2015       $5,000.00
 CARDIOLOGY FOUNDATION    Board Review for
                          Certification and
                          Recertification
------------------------------------------------------------------------
CANCER RESEARCH          Immunotherapy for    05/19/2015      $75,000.00
 INSTITUTE                the Oncology
                          Nurse
------------------------------------------------------------------------
GORDON RESEARCH          Gordon Research      05/20/2015       $5,000.00
 CONFERENCES              Conference;
                          Hormone dependent
                          cancer
------------------------------------------------------------------------
NORTHEASTERN UNIVERSITY  Boston Symposium     05/21/2015       $3,500.00
                          on Organic and
                          Bioorganic
                          Chemistry (BSOBC)
------------------------------------------------------------------------
AMERICAN SOCIETY OF      Anemia,              05/21/2015     $190,000.00
 NEPHROLOGY               Erythropoeisis,
                          and the
                          Nephrologist
------------------------------------------------------------------------
CANCER RESEARCH          2015 International   05/24/2015      $50,000.00
 INSTITUTE                Cancer
                          Immunotherapy
                          Conference
------------------------------------------------------------------------
ZOE ROSE MEMORIAL        2015 Preemie         05/24/2015      $10,000.00
 FOUNDATION               Parent Summit
------------------------------------------------------------------------
THE GOG FOUNDATION INC   4th Semi Annual      05/26/2015      $20,000.00
                          Meeting of NRG
                          Oncology
                          (formerly GOG,
                          NSABP, RTOG)
------------------------------------------------------------------------
CLINICAL CARE OPTIONS    Immunotherapy for    05/26/2015      $25,000.00
                          Cancer Track: CCO
                          Independent
                          Conference
                          Highlights of the
                          2015 ASCO Annual
                          Meeting
------------------------------------------------------------------------
ACADEMIA MEDICA DEL SUR  Non-Small Cell       05/26/2015       $3,000.00
                          Lung Cancer:
                          Current Therapy
                          and Promising New
                          Regimens
------------------------------------------------------------------------
AMERICAN                 ANMS 10th            05/26/2015       $6,400.00
 NEUROGASTROENTEROLOGY    Postgraduate
 AND MOTILITY SOCIETY     Course in
                          Gastroenterology
                          and
                          Neurogastroentero
                          logy in Clinical
                          Practice
------------------------------------------------------------------------
CEO ROUNDTABLE ON        Prostate Cancer      05/27/2015      $30,000.00
 CANCER, INC.             DREAM Challenge
                          Winning Teams
                          Educational Grant
------------------------------------------------------------------------
C-CHANGE                 Big Data in Cancer   05/27/2015      $25,000.00
                          Care
------------------------------------------------------------------------
THE GOG FOUNDATION       Rational             05/27/2015      $10,000.00
                          Combination
                          Targeted
                          Therapies for
                          Gynecologic
                          Cancers
------------------------------------------------------------------------
TRUSTEES OF COLUMBIA     Lung Cancer 2015:    05/27/2015       $3,000.00
 UNIVERSITY IN THE CITY   New Discoveries,
 OF NEW YORK              New Directions
------------------------------------------------------------------------
NOT-FOR-PROFIT HOSPITAL  Lung Cancer          05/27/2015       $1,900.00
 CORPORATION              Screening in 2015
------------------------------------------------------------------------
OLIGONUCLEOTIDE          11th Annual          05/31/2015       $7,500.00
 THERAPEUTICS SOCIETY     Meeting of the
                          Oligonucleotide
                          Therapeutics
                          Society
------------------------------------------------------------------------
CONQUER CANCER           2015 Best of ASCO    05/31/2015      $15,000.00
 FOUNDATION OF THE        Meetings
 AMERICAN SOCIETY OF
 CLINICAL ONCOLOGY
------------------------------------------------------------------------
AMERICAN ASSOCIATION OF  Improving Outcomes   06/02/2015     $101,800.00
 DIABETES EDUCATORS       for Women With
                          Type 2 Diabetes
                          Individualizing
                          Evidence-Based
                          Care
------------------------------------------------------------------------
NATIONAL KIDNEY          Chronic Kidney       06/02/2015      $75,000.00
 FOUNDATION               Disease and the
                          Primary Care
                          Practitioner:
------------------------------------------------------------------------
UNIVERSITY OF MARYLAND   17th Annual          06/02/2015      $15,000.00
 BALTIMORE FOUNDATION,    International
 INC.                     Meeting of the
                          Institute of
                          Human Virology
------------------------------------------------------------------------
TRUSTEES OF THE          2015 Updates in      06/03/2015       $5,000.00
 UNIVERSITY OF            Oncology: With
 PENNSYLVANIA             Proceedings from
                          International
                          Medical Meetings
------------------------------------------------------------------------
MELANOMA RESEARCH        Melanoma Research    06/03/2015     $112,280.00
 FOUNDATION               Foundation CURE
                          OM Junior
                          Fellowship
------------------------------------------------------------------------
AMERICAN OSTEOPATHIC     Optimizing Anti-     06/04/2015     $357,790.00
 ASSOCIATION              platelet Therapy
                          and Secondary
                          Prevention
                          Strategies in
                          Acute Coronary
                          Syndromes The
                          Role of the
                          Primary Care
                          Practice
                          (150203494)
------------------------------------------------------------------------
INTERNATIONAL SOCIETY    Workshop on          06/09/2015      $30,000.00
 FOR STEM CELL RESERACH   Clinical
                          Translation
------------------------------------------------------------------------
NURSE PRACTITIONER       The Latest in        06/10/2015       $5,000.00
 ASSOCIATES FOR           Asthma and COPD
 CONTINUING EDUCATION
 (NPACE)
------------------------------------------------------------------------
AMERICAN PHARMACISTS     IMPACT Care          06/10/2015      $74,987.00
 ASSOCIATION FOUNDATION   Transformation
                          Institute
------------------------------------------------------------------------
AMERICAN ASSOCIATION     Advances in Breast   06/11/2015      $10,000.00
 FOR CANCER RESEARCH      Cancer Research
------------------------------------------------------------------------
AMERICAN ASSOCIATION     Advances in          06/11/2015      $10,000.00
 FOR CANCER RESEARCH      Ovarian Cancer
                          Research
------------------------------------------------------------------------
AMERICAN COLLEGE OF      Symposium--Asthma,   06/11/2015      $50,000.00
 ALLERGY, ASTHMA AND      COPD and Asthma-
 IMMUNOLOGY               COPD Overlap
                          Syndrome (ACOS)
------------------------------------------------------------------------
CASE MANAGEMENT SOCIETY  Improving            06/11/2015       $6,265.00
 OF AMERICA               Medication
                          Adherence in the
                          COPD Patient
                          through Greater
                          Patient
                          Engagement
------------------------------------------------------------------------
AMERICAN ASSOCIATION OF  California Chapter   06/16/2015      $20,000.00
 CLINICAL                 of the American
 ENDOCRINOLOGISTS         Association of
                          Clinical
                          Endocrinologists
                          Presents: Hot
                          Topics in
                          Diabetes and
                          Endocrinology for
                          Primary Care
------------------------------------------------------------------------
FLORIDA ACADEMY OF       Update on COPD and   06/16/2015       $4,300.00
 PHYSICIAN ASSISTANTS     Asthma Management
 INC.
------------------------------------------------------------------------
AMERICAN ACADEMY OF      2015 AAFP FMX        06/16/2015      $13,000.00
 FAMILY PHYSICIANS        Assembly 60
                          Minute Lecture
                          titled Acute
                          Coronary Syndrome
                          and Angina
------------------------------------------------------------------------
AMERICAN COLLEGE OF      ACEP Pediatric       06/17/2015       $2,500.00
 EMERGENCY PHYSICAINS     Emergency
                          Medicine Special
                          Interest Section
                          Annual Meeting
------------------------------------------------------------------------
FOUNDATION FOR           FGO Genetics         06/18/2015      $35,000.00
 GYNECOLOGIC ONCOLOGY     Summit
------------------------------------------------------------------------
FRIENDS OF CANCER        2015 Friends of      06/22/2015     $100,000.00
 RESEARCH                 Cancer Research
                          Programs
------------------------------------------------------------------------
DIVISION OF MEDICINAL    Division of          06/23/2015       $2,500.00
 CHEMISTRY                Medicinal
                          Chemistry Program
                          American Chemical
                          Society 250th
                          National Meeting
------------------------------------------------------------------------
RECTOR AND VISITORS OF   Vasculata 2015       06/24/2015      $10,000.00
 THE UNIVERSITY OF
 VIRGINIA
------------------------------------------------------------------------
AMERICAN COLLEGE OF      Preventing           06/24/2015      $48,000.00
 CHEST PHYSICIANS         Exacerbations of
                          COPD
------------------------------------------------------------------------
ASSOCIATION OF ASTHMA    The Asthma Team:     06/24/2015       $5,000.00
 EDUCATORS                Making Wishes
                          Come True
------------------------------------------------------------------------
THE MASSACHUSETTS        30th Annual          06/24/2015       $5,000.00
 GENERAL HOSPITAL         Critical Issues
                          In Tumor
                          Microenvironment:
                          Angiogenesis,
                          Metastasis and
                          Immunology
------------------------------------------------------------------------
NATIONAL MEDICAL         The National         06/24/2015       $3,000.00
 ASSOCIATION              Medical
                          Association
                          Asthma Update:
                          Evidence-Based
                          Diagnosis and
                          management of
                          Asthma--Practical
                          Tools to Improve
                          Patient Care
------------------------------------------------------------------------
NATIONAL ASSOCIATION OF  Reducing             06/25/2015      $12,500.00
 MANAGED CARE             Exacerbations in
 PHYSICIANS               the Treatment and
                          Management of
                          Chronic
                          Obstructive
                          Pulmonary Disease
                          (COPD)
------------------------------------------------------------------------
ONCOLOGY NURSING         Pharmacology         06/30/2015      $15,000.00
 SOCIETY                  Updates in
                          Oncology Practice
                          Conference
------------------------------------------------------------------------
UC BERKELEY FOUNDATION   IGI CRISPR           06/30/2015      $10,000.00
                          Workshop: Routes
                          to Designer
                          Biology
------------------------------------------------------------------------
METABOLIC ENDOCRINE      13th Annual World    07/01/2015     $100,000.00
 EDUCATION FOUNDATION     Congress on
                          Insulin
                          Resistance
                          Diabetes and
                          Cardiovascular
                          Disease--WCIRDC
------------------------------------------------------------------------
PARTNERS HEALTHCARE      2015 Personalized    07/02/2015      $25,000.00
 PERSONALIZED MEDICINE    Medicine
                          Conference
------------------------------------------------------------------------
NATIONAL ASSOCIATION OF  Improving Patient    07/02/2015      $25,000.00
 MANAGED CARE             Outcomes with
 PHYSICIANS, INC.         Novel Treatments
                          in the Management
                          of
                          Hypertriglyceride
                          mia
------------------------------------------------------------------------
NEW YORK CITY SOCIETY    Practical            07/07/2015       $9,500.00
 OF HEALTH- SYSTEM        considerations
 PHARMACISTS              for using novel
                          oral antiplatelet
                          agents in
                          patients with
                          acute coronary
                          syndromes
------------------------------------------------------------------------
INTERNATIONAL            EGFR Diagnostic      07/09/2015     $201,000.00
 ASSOCIATION FOR THE      Expert Consensus
 STUDY OF LUNG CANCER     meeting
------------------------------------------------------------------------
UB FOUNDATION            Recent Advances in   07/09/2015       $2,500.00
 ACTIVITIES, INC.         the
                          pathophysiology
                          and management of
                          type 2 diabetes
------------------------------------------------------------------------
AMERICAN PHARMACISTS     APhA's Pharmacist    07/14/2015      $25,000.00
 ASSOCIATION              and Patient
                          Centered Diabetes
                          Care Certificate
                          Training Program
                          National
                          Offerings
------------------------------------------------------------------------
AMERICAN ASSOCIATION     AACR-NCI-EORTC       07/14/2015      $25,000.00
 FOR CANCER RESEARCH      Molecular Targets
                          and Cancer
                          Therapeutics
------------------------------------------------------------------------
JOHNS HOPKINS            Mid-Atlantic         07/14/2015      $49,381.58
 UNIVERSITY SCHOOL OF     Nephrology Young
 MEDICINE                 Investigators'
                          Forum
------------------------------------------------------------------------
SOUTH DAKOTA ACADEMY OF  COPD: diagnosis      07/14/2015       $3,500.00
 PHYSICIAN ASSISTANTS     and optimum
                          treatment
------------------------------------------------------------------------
SOUTHERN SOCIETY FOR     15th Annual SSCI     07/15/2015      $43,940.49
 CLINICAL INVESTIGATION   Nephrology Young
                          Investigators'
                          Forum
------------------------------------------------------------------------
YALE UNIVERSITY          2015 London          07/16/2015       $5,000.00
                          Cardiovascular
                          Device Innovation
                          Summit
------------------------------------------------------------------------
REGENTS OF THE           Updates in           07/19/2015       $5,000.00
 UNIVERSITY OF            Rheumatology 2015
 CALIFORNIA
------------------------------------------------------------------------
REGENTS OF THE           13th Annual          07/21/2015      $34,698.53
 UNIVERSITY OF            Nephrology Young
 CALIFORNIA               Investigator's
                          Forum
------------------------------------------------------------------------
SOCIETY FOR              2015 SITC            07/22/2015      $50,000.00
 IMMUNOTHERAPY OF         International
 CANCER                   Symposium on
                          Cancer
                          Immunotherapy
------------------------------------------------------------------------
SOCIETY FOR              SITC 2015 Global     07/22/2015      $25,000.00
 IMMUNOTHERAPY OF         Regulatory Summit
 CANCER
------------------------------------------------------------------------
NATIONAL COMPREHENSIVE   NCCN/SCCA 2015       07/26/2015      $10,000.00
 CANCER NETWORK, INC.     Thoracic Oncology
                          Symposium
------------------------------------------------------------------------
SOCIETY FOR              Named Postdoctoral   07/26/2015     $120,000.00
 IMMUNOTHERAPY OF         Cancer
 CANCER                   Immunotherapy in
                          NSCLC Clinical
                          Fellowship Award
------------------------------------------------------------------------
NATIONAL ASSOCIATION     Gout: Bridging       07/26/2015     $163,946.00
 FOR CONTINUING           Knowledge Gaps in
 EDUCATION                Diagnosis and
                          Treatment
------------------------------------------------------------------------
NATIONAL COMPREHENSIVE   2015 NCCN Immuno-    07/26/2015      $35,000.00
 CANCER NETWORK, INC.     Oncology Webinar
                          Series for
                          Pharmacists
------------------------------------------------------------------------
AMERICAN COLLEGE OF      EPC--Updates in      07/28/2015      $10,000.00
 ALLERGY, ASTHMA AND      Pulmonary
 IMMUNOLOGY               Disease: Current,
                          Relevant and
                          Interactive
------------------------------------------------------------------------
NATIONAL KIDNEY          11th Annual          07/29/2015      $50,000.00
 FOUNDATION               National Young
                          Investigator's
                          Forum
------------------------------------------------------------------------
JOHNS HOPKINS            Immuno-Oncology: A   07/29/2015      $30,000.00
 UNIVERSITY SCHOOL OF     Revolution in
 MEDICINE                 Cancer Treatment
------------------------------------------------------------------------
GEORGIA CHAPTER OF THE   2015 Scientific      07/30/2015       $5,000.00
 AMERICAN COLLEGE OF      Meeting
 CARDIOLOGY
------------------------------------------------------------------------
NATIONAL ASSOCIATION OF  Improving Outcomes   08/02/2015      $25,000.00
 MANAGED CARE             with
 PHYSICIANS, INC.         Individualized
                          Treatment
                          Strategies in the
                          Management of
                          Advanced Non
                          Small-Cell Lung
                          Cancer (NSCLC)
------------------------------------------------------------------------
HACKENSACK UNIVERSITY    Fifth Annual Heart   08/03/2015       $5,000.00
 MEDICAL CENTER           and Vascular
                          Symposium
------------------------------------------------------------------------
METABOLIC ENDOCRINE      Early Intervention   08/06/2015     $149,515.00
 EDUCATION FOUNDATION     in The Continuum
                          of Hyperglycemia--
                          The Role of
                          Initial
                          Combination
                          Therapy
------------------------------------------------------------------------
SOCIETY FOR              Primer on Tumor      08/10/2015      $15,000.00
 IMMUNOTHERAPY OF         Immunology and
 CANCER                   Cancer
                          Immunotherapy
------------------------------------------------------------------------
NATIONAL COMPREHENSIVE   NCCN/SCCA 2015       08/11/2015      -$2,005.40
 CANCER NETWORK, INC.     Thoracic Oncology
                          Symposium
------------------------------------------------------------------------
CONQUER CANCER           2015 Breast Cancer   08/11/2015      $10,000.00
 FOUNDATION OF THE        Symposium:
 AMERICAN SOCIETY OF      Enhancing
 CLINICAL ONCOLOGY        Clinical Care
                          through
                          Collaboration
------------------------------------------------------------------------
AMERICAN ACADEMY OF      Management of        08/11/2015     $242,009.00
 FAMILY PHYSICIANS        Gout:
                          Individualizing
                          the Approach
------------------------------------------------------------------------
BREATHE CALIFORNIA OF    Advancing the        08/16/2015       $3,000.00
 LOS ANGELES COUNTY       diagnosis and
                          management of
                          COPD with a focus
                          on COPD
                          exacerbations
------------------------------------------------------------------------
GLOBAL ACADEMY FOR       8th Annual           08/17/2015      $35,000.00
 MEDICAL EDUCATION        Perspectives in
                          Rheumatic
                          Diseases
                          presented by
                          Rheumatology
                          News, Internal
                          Medicine News,
                          Family Practice
                          News
------------------------------------------------------------------------
NORTHWESTERN UNIVERSITY  17th Annual Lynn     08/17/2015      $10,000.00
                          Sage Breast
                          Cancer Symposium
------------------------------------------------------------------------
AMERICAN COLLEGE OF      Cardiovascular       08/17/2015      $10,000.00
 EMERGENCY PHYSICIANS     Disease Track at
                          ACEP 2015
                          Scientific
                          Assembly
------------------------------------------------------------------------
NATIONAL ASSOCIATION OF  NANN 31st Annual     08/19/2015      $10,000.00
 NEONATAL NURSES          Educational
                          Conference
------------------------------------------------------------------------
UNIVERSITY OF            2nd Annual           08/19/2015      $25,000.00
 CINCINNATI               Cincinnati
                          Collaborative
                          Cardiovascular
                          Symposium (C4)
------------------------------------------------------------------------
AMERICAN ASSOCIATION OF  AACE/ACE             08/20/2015      $99,804.71
 CLINICAL                 Scientific and
 ENDOCRINOLOGISTS         Clinical Review
                          of DKA and the
                          Effects of SGLT2
                          Inhibitors
------------------------------------------------------------------------
AMERICAN COLLEGE OF      TAS: Allergy,        08/23/2015       $1,000.00
 ALLERGY, ASTHMA AND      Asthma and
 IMMUNOLOGY               Immunology
                          Conference
------------------------------------------------------------------------
NAMI MARYLAND            NAMI Maryland 2015   08/25/2015       $5,000.00
                          Annual Education
                          Conference
------------------------------------------------------------------------
CONNECTICUT PHARMACISTS  Insights, Pearls,    08/25/2015       $5,000.00
 ASSOCIATION              and Perspectives--
                          An Update in the
                          Management of
                          Chronic
                          Obstructive
                          Pulmonary Disease
------------------------------------------------------------------------
AMERICAN COLLEGE OF      Plenary Session--    08/25/2015      $50,000.00
 ALLERGY, ASTHMA AND      Updates in Severe
 IMMUNOLOGY               Asthma
------------------------------------------------------------------------
UNIVERSITY OF FLORIDA    Vascular Biology     08/26/2015      $10,000.00
                          Working Group
                          Global Chapter
                          Meeting
------------------------------------------------------------------------
PENN STATE UNIVERSITY    Skin, Bones,         08/26/2015       $5,000.00
                          Hearts and
                          Private Parts
------------------------------------------------------------------------
AMERICAS HEALTH          Roundtable           08/27/2015      $37,462.15
 FOUNDATION               Discussion on
                          Decreasing the
                          Burden of
                          Influenza in
                          Latin America
------------------------------------------------------------------------
DANA-FARBER CANCER       11th Annual          08/27/2015       $2,500.00
 INSTITUTE INC.           Postdoctoral and
                          Graduate Student
                          Retreat
------------------------------------------------------------------------
IOWA PHYSICIAN           COPD Board Review    08/27/2015       $2,000.00
 ASSISTANT SOCIETY        Track
------------------------------------------------------------------------
BAYLOR COLLEGE OF        Breast Cancer        08/30/2015       $3,000.00
 MEDICINE                 Research and
                          Education Program
------------------------------------------------------------------------
BAYLOR COLLEGE OF        Metastatic Breast    08/30/2015       $3,500.00
 MEDICINE                 Cancer Conference
------------------------------------------------------------------------
ICAHN SCHOOL OF          Top Ten Advances     08/30/2015      $10,000.00
 MEDICINE AT MOUNT        in Clinical
 SINAI                    Cardiology
------------------------------------------------------------------------
ASSOCIATION OF           In the Era of        09/01/2015     $125,000.00
 COMMUNITY CANCER         Value: The
 CENTERS                  Importance of
                          Patient
                          Navigation,
                          Psychosocial
                          Distress
                          Screening, and
                          Survivorship Care
                          Planning Programs
                          in the Community
                          C
------------------------------------------------------------------------
PENNSYLVANIA STATE       Constipation:        09/02/2015     $142,387.00
 UNIVERSITY               Improving
                          Outcomes With
                          Individualized,
                          Evidence-based
                          Treatment
------------------------------------------------------------------------
SIDNEY KIMMEL MEDICAL    2nd Annual Current   09/03/2015       $5,000.00
 COLLEGE AT THOMAS        Issues in
 JEFFERSON UNIVERSITY     Coronary and
                          Structural Heart
                          Disease: A
                          Multidisciplinary
                          Approach
------------------------------------------------------------------------
AMERICAN COLLEGE OF      48th Annual New      09/08/2015      $15,000.00
 CARDIOLOGY FOUNDATION    York
                          Cardiovascular
                          Symposium: Major
                          Topics in
                          Cardiology Today
------------------------------------------------------------------------
AMERICAN SOCIETY FOR     ASTRO's 57th         09/09/2015      $10,000.00
 RADIATION ONCOLOGY       Annual Meeting
------------------------------------------------------------------------
NATIONAL JEWISH HEALTH   38th Annual          09/14/2015       $5,000.00
                          Pulmonary and
                          Allergy Update
------------------------------------------------------------------------
ST. JOSEPH'S REGIONAL    Acute Myocardial     09/14/2015       $1,700.00
 MEDICAL CENTER           Infarction:
                          Guidelines,
                          Controversies and
                          Updates
------------------------------------------------------------------------
TRUSTEES OF BOSTON       Head and Neck        09/15/2015       $3,000.00
 UNIVERSITY               Cancer Symposium:
                          From Pathways to
                          Therapies
------------------------------------------------------------------------
UNIVERSITY OF TEXAS      Cancer Genetics:     09/15/2015       $3,000.00
 SOUTHWESTERN MEDICAL     Going Beyond the
 CENTER                   Guidelines
------------------------------------------------------------------------
THE UNIVERSITY OF TEXAS  38TH Annual San      09/15/2015      $25,000.00
 HEALTH SCIENCE CENTER    Antonio Breast
 AT SAN ANTONIO           Cancer Symposium
------------------------------------------------------------------------
BAYLOR UNIVERSITY        The 42nd Annual      09/15/2015       $8,500.00
 MEDICAL CENTER           Williamsburg
                          Conference on
                          Heart Disease
------------------------------------------------------------------------
UNIVERSITY OF            Comprehensive        09/15/2015       $3,500.00
 WASHINGTON               Hematology and
                          Oncology Review
------------------------------------------------------------------------
NATIONAL COMMITTEE FOR   NCQA Quality Talks   09/15/2015      $25,000.00
 QUALITY ASSURANCE        and 25th
                          Anniversary
------------------------------------------------------------------------
ICAHN SCHOOL OF          Acute Myocardial     09/15/2015       $1,400.00
 MEDICINE AT MOUNT        Infarction:
 SINAI                    Guidelines,
                          Controversies and
                          Updates
------------------------------------------------------------------------
CONQUER CANCER           2015 Breast Cancer   09/16/2015      $25,000.00
 FOUNDATION OF THE        Symposium
 AMERICAN SOCIETY OF      Proceedings
 CLINICAL ONCOLOGY
------------------------------------------------------------------------
UT HEALTH SCIENCE        38th Annual San      09/16/2015      $35,000.00
 CENTER SAN ANTONIO       Antonio Breast
                          Cancer Symposium--
                          Basic Science
                          Forum/Poster
                          Discussion
                          Session
------------------------------------------------------------------------
AULTMAN HOSPITAL         Aultman Hospital's   09/17/2015       $2,500.00
                          15th Annual
                          Cancer Conference
------------------------------------------------------------------------
AMERICAN COLLEGE OF      Recognizing          09/20/2015     $209,619.96
 EMERGENCY PHYSICIANS     Diabetic
                          Emergencies: Will
                          You Be Ready?
------------------------------------------------------------------------
INTERNATIONAL            Best of the World    09/21/2015      $10,000.00
 ASSOCIATION FOR THE      Conference on
 STUDY OF LUNG CANCER     Lung Cancer
------------------------------------------------------------------------
CONQUER CANCER           CancerLinQ: Real-    09/21/2015     $400,000.00
 FOUNDATION OF THE        time Learning
 AMERICAN SOCIETY OF      Intelligence
 CLINICAL ONCOLOGY        Network for
                          Quality
------------------------------------------------------------------------
LUNG CANCER INITIATIVE   Advanced             09/22/2015       $3,000.00
 OF NC                    Laboratory
                          Testing Across
                          Cancer Types:
                          Everything you
                          need to know
------------------------------------------------------------------------
CAROLINAS HEALTHCARE     27th Annual Fall     09/22/2015       $3,000.00
 SYSTEM                   Foliage Cancer
                          Conference
                          ``Update on Lung
                          Cancer''
------------------------------------------------------------------------
SCRIPPS HEALTH           TRANSFORMING         09/23/2015       $2,000.00
                          MEDICINE:
                          Evidence-Driven
                          mHealth
------------------------------------------------------------------------
WESTERN SOCIETY OF       WSAAI 54th Annual    09/23/2015      $10,000.00
 ALLERGY, ASTHMA AND      Scientific
 IMMUNOLOGY               Session
------------------------------------------------------------------------
CONQUER CANCER           2016 Conquer         09/23/2015     $120,000.00
 FOUNDATION OF THE        Cancer Foundation
 AMERICAN SOCIETY OF      of ASCO Young
 CLINICAL ONCOLOGY        Investigator
                          Award (YIA)
------------------------------------------------------------------------
ASSOCIATION OF AMERICAN  2015 AACI/CCAF       09/28/2015      $10,000.00
 CANCER INSTITUTES        Annual Meeting
------------------------------------------------------------------------
CONQUER CANCER           2016 Conquer         09/29/2015      $40,000.00
 FOUNDATION OF THE        Cancer Foundation
 AMERICAN SOCIETY OF      of ASCO Merit
 CLINICAL ONCOLOGY        Awards
------------------------------------------------------------------------
NATIONAL ASSOCIATION OF  2016 NAHN            09/29/2015      $10,000.00
 HISPANIC NURSES          Leadership
                          Meeting
------------------------------------------------------------------------
AMERICAN ACADEMY OF      2015 AAFP FMX        09/30/2015       $5,000.00
 FAMILY PHYSICIANS        Assembly 60
                          Minute Lecture
                          titled Chronic
                          Obstructive
                          Pulmonary Disease
                          (COPD) and
                          Pulmonary
                          Function Testing
------------------------------------------------------------------------
NORTHWESTERN UNIVERSITY  2nd Annual Case-     09/30/2015       $5,000.00
                          Based Coronary
                          and Structural
                          Heart
                          Intervention
                          Update
------------------------------------------------------------------------
TRUSTEES OF THE          44th Annual          10/04/2015       $5,000.00
 UNIVERSITY OF            Philadelphia
 PENNSYLVANIA             Workshop on
                          Hemostasis,
                          Thrombosis and
                          Artherosclerosis
------------------------------------------------------------------------
ECOG RESEARCH AND        ECOG-ACRIN Fall      10/05/2015       $5,000.00
 EDUCATION FOUNDATION,    2015 Group
 INC.                     Meeting
------------------------------------------------------------------------
PHARMACY QUALITY         Getting to the       10/05/2015       $3,500.00
 ALLIANCE (PQA, INC)      Core: Building
                          and Implementing
                          Core Measures
------------------------------------------------------------------------
BAYLOR UNIVERSITY        Immune Checkpoint    10/07/2015       $5,000.00
 MEDICAL CENTER           Inhibitors in the
                          Treatment of
                          Selected Tumor
                          Types: A New
                          Prospective
------------------------------------------------------------------------
CEDARS SINAI MEDICAL     4th Annual New       10/07/2015       $5,000.00
 CENTER                   Therapeutics in
                          Oncology: The
                          Road to
                          Personalized
                          Medicine
------------------------------------------------------------------------
PENN STATE UNIVERSITY    Skin, Bones,         10/07/2015       $5,000.00
                          Hearts and
                          Private Parts
                          (two conferences)
------------------------------------------------------------------------
INDIANA UNIVERSITY       Performance          10/07/2015       $5,000.00
                          Improvement with
                          Point of Care
                          Clinical Decision
                          Making App in non-
                          ST segment
                          elevation
                          myocardial
                          infarction
                          (NSTEMI) patients
------------------------------------------------------------------------
MEDSTAR WASHINGTON       Update In            10/08/2015      $15,000.00
 HOSPITAL CENTER          Rheumatology
                          2015: New
                          Diagnostic Tests
                          and Treatments
                          for Clinical
                          Practice
------------------------------------------------------------------------
NEW YORK STATE           New York State       10/08/2015       $2,500.00
 OSTEOPATHIC MEDICAL      Osteopathic
 SOCIETY                  Medical Students
                          Health Policy
                          Initiative
------------------------------------------------------------------------
THE UNIVERSITY OF TEXAS  2015 Oncologic       10/11/2015       $5,000.00
 MD ANDERSON CANCER       Emergency
 CENTER                   Medicine
                          Conference
------------------------------------------------------------------------
AMERICAN PANCREATIC      46th Annual          10/11/2015      $10,000.00
 ASSOCIATION              Meeting of the
                          American
                          Pancreatic
                          Association
------------------------------------------------------------------------
WAYNE STATE UNIVERSITY   2nd Annual Update    10/15/2015       $3,000.00
 SCHOOL OF MEDICINE       in Rheumatology
------------------------------------------------------------------------
WAYNE STATE UNIVERSITY   State of the Art     10/15/2015       $3,000.00
                          Management of
                          Lung Cancer
                          Symposium
------------------------------------------------------------------------
MEDICAL UNIVERSITY OF    2nd Annual           10/18/2015      $10,000.00
 SOUTH CAROLINA           Comprehensive
                          Stroke and
                          Cerebrovascular
                          Update
------------------------------------------------------------------------
AMERICAN COLLEGE OF      2015                 10/19/2015      $25,000.00
 RHEUMATOLOGY             Musculoskeletal
                          Ultrasound Course
                          for
                          Rheumatologists
------------------------------------------------------------------------
LOUISIANA STATE          LSUHSC               10/20/2015       $3,500.00
 UNIVERSITY HEALTH        Cardiovascular
 SCIENCES CENTER IN NEW   Centers Joint
 ORLEANS                  Retreat
------------------------------------------------------------------------
AMERICAN ASSOCIATION OF  Achieving            10/20/2015     $389,000.00
 DIABETES EDUCATORS       Partnerships and
                          Improving
                          Outcomes in Your
                          Diabetes Patients
------------------------------------------------------------------------
THE ENDOCRINE SOCIETY    The Truth of the     10/21/2015     $284,438.73
                          Matter: An
                          Evidence-Based
                          Review of the
                          Newer
                          Antihyperglycemic
                          Agents for T2DM:
                          a hot seat
                          Program
------------------------------------------------------------------------
GORDON RESEARCH          2016 Basal Ganglia   10/21/2015       $2,500.00
 CONFERENCES              Gordon Research
                          Conference:
                          Emerging Views of
                          Cellular and
                          Circuit Diversity
                          Within the Basal
                          Ganglia
------------------------------------------------------------------------
MEDSTAR WASHINGTON       Lung Cancer 2015:    10/22/2015       $3,000.00
 HOSPITAL CENTER          A Shifting
                          Management
                          Paradigm with
------------------------------------------------------------------------
NATIONAL QUALITY FORUM   NQF Measure          10/22/2015     $100,000.00
                          Incubator
------------------------------------------------------------------------
GORDON RESEARCH          2016 Gordon          10/26/2015       $2,500.00
 CONFERENCES              Research
                          Conference on
                          Heterocyclic
                          Compounds
------------------------------------------------------------------------
AMERICAN HEART           Scientific           10/26/2015      $30,000.00
 ASSOCIATION, INC.        Sessions 2015
                          Dedicated Track
                          on Acute Coronary
                          Syndrome: Current
                          and Emerging
                          Interventions and
                          Future Directions
------------------------------------------------------------------------
INOVA HEALTH CARE        Inova Heart and      11/03/2015      $15,000.00
 SERVICES                 Vascular
                          Institute 2016
                          Interventional
                          Cardiology
                          Symposium
------------------------------------------------------------------------
AMERICAN ASSOCIATION OF  17th Annual          11/04/2015      $20,000.00
 CLINICAL                 Intensive Course
 ENDOCRINOLOGISTS         on Diabetes,
                          Endocrinology,
                          and Metabolic
                          Diseases
------------------------------------------------------------------------
WORLDWIDE INITIATIVE     Novel Therapies in   11/05/2015      $77,050.00
 FOR DIABETES EDUCATION   Type 2 Diabetes
                          Mellitus
------------------------------------------------------------------------
AMERICAN ASSOCIATION OF  AACE/ACE             11/05/2015      $79,500.00
 CLINICAL                 Comprehensive
 ENDOCRINOLOGISTS         Diabetes
                          Algorithm 2015
                          Mobile App
------------------------------------------------------------------------
GORDON RESEARCH          GRC Mutagenesis      11/05/2015       $3,500.00
 CONFERENCE               meeting 2016
------------------------------------------------------------------------
ONCOLOGY NURSING         InPractice           11/09/2015      $49,000.00
 SOCIETY                  Oncology Nursing
------------------------------------------------------------------------
PARTNERS HEALTHCARE      World Medical        11/22/2015      $50,000.00
 SYSTEM INC.              Innovation Forum
------------------------------------------------------------------------
AMERICAN ASSOCIATION     AACR-IASLC Joint     11/22/2015      $25,000.00
 FOR CANCER RESEARCH      Conference on the
                          Molecular Origins
                          of Lung Cancer
------------------------------------------------------------------------
PREVENTIVE               Cardiovascular       11/22/2015      $10,000.00
 CARDIOVASCULAR NURSES    Risk Reduction:
 ASSOCIATION              Leading the Way
                          in Prevention
                          (22nd Annual
                          Symposium)
------------------------------------------------------------------------
NATIONAL LIPID           National Lipid       11/22/2015      $15,000.00
 ASSOCIATION              Association 2016
                          Lipid Academy
                          Course Series
------------------------------------------------------------------------
NATIONAL LIPID           National Lipid       11/22/2015      $15,000.00
 ASSOCIATION              Association 2016
                          Masters in
                          Lipidology Course
                          Series
------------------------------------------------------------------------
THE DEUEL CONFERENCE ON  The 2016 Deuel       11/24/2015      $20,000.00
 LIPIDS                   Conference on
                          Lipids
------------------------------------------------------------------------
AMERICAN PHARMACISTS     APhA2016             11/25/2015      $11,500.00
 ASSOCIATION              Respiratory
                          Update:
                          Guidelines, Novel
                          Inhalers and More
------------------------------------------------------------------------
REGENTS OF THE           2016 World           12/01/2015      $10,000.00
 UNIVERSITY OF            Congress on
 CALIFORNIA               Continuing
                          Professional
                          Development:
                          Advancing
                          Learning and Care
                          in the Health
                          Professions
------------------------------------------------------------------------
NASPGHAN FOUNDATION      Appropriate Use of   12/01/2015     $185,000.00
                          Proton Pump
                          Inhibitors in the
                          Treatment of
                          Pediatric
                          Patients with
                          GERD
------------------------------------------------------------------------
TRUSTEES OF BOSTON       A COPD Quality       12/01/2015     $139,644.64
 UNIVERSITY               Improvement
                          Consortium
------------------------------------------------------------------------
FOUNDATION FOR           Evolution and        12/03/2015     $200,000.00
 GYNECOLOGIC ONCOLOGY     Revolution of
                          PARP Targeting in
                          Gynecologic
                          Malignancies
------------------------------------------------------------------------
AMERICAN FEDERATION FOR  2016 Western         12/03/2015       $5,000.00
 MEDICAL RESEARCH         Regional Meeting
------------------------------------------------------------------------
UNIVERSITY OF            University of        12/06/2015      $19,942.22
 WASHINGTON               Washington
                          Allergy and
                          Immunology
                          Fellowship
------------------------------------------------------------------------
NATIONAL COMPREHENSIVE   NCCN 2016 Congress   12/09/2015      $25,000.00
 CANCER NETWORK, INC.     Series: Breast
                          Cancer
------------------------------------------------------------------------
AMERICAN SOCIETY FOR     2016                 12/10/2015      $10,000.00
 RADIATION ONCOLOGY       Multidisciplinary
                          Head and Neck
                          Cancer Symposium
------------------------------------------------------------------------
NATIONAL COMPREHENSIVE   NCCN 21st Annual     12/10/2015      $75,000.00
 CANCER NETWORK, INC.     Conference
                          General Session:
                          Advancing the
                          Standard of
                          Cancer CareTM
------------------------------------------------------------------------
AMERICAN ASSOCIATION     AACR Annual          12/10/2015     $125,000.00
 FOR CANCER RESEARCH      Meeting--2016
------------------------------------------------------------------------
AMERICAN FEDERATION FOR  2016 Southern        12/10/2015       $5,000.00
 MEDICAL RESEARCH         Regional Meeting
------------------------------------------------------------------------
NATIONAL COMPREHENSIVE   NCCN 2016 Nursing    12/13/2015      $25,000.00
 CANCER NETWORK, INC.     Program:
                          Advancing
                          Oncology Nursing
                          at the NCCN 21st
                          Annual Conference
------------------------------------------------------------------------
INTERNATIONAL            16th Targeted        12/13/2015      $82,500.00
 ASSOCIATION FOR THE      Therapy meeting
 STUDY OF LUNG CANCER     on Lung Cancer
------------------------------------------------------------------------
AMERICAN                 Opioid-Induced       12/13/2015     $192,601.00
 GASTROENTEROLOGICAL      Constipation:
 ASSOCIATION              Recognition and
                          Optimal
                          Management
------------------------------------------------------------------------
KANAWHA COUNTY           Mobile Integrated    12/14/2015      $50,000.00
 EMERGENCY AMBULANCE      Health Program:
 AUTHORITY                Emphasis on
                          Community
                          Paramedicine
------------------------------------------------------------------------
INTERNATIONAL            PDL1 Atlas           12/14/2015     $120,000.00
 ASSOCIATION FOR THE
 STUDY OF LUNG CANCER
------------------------------------------------------------------------
CONQUER CANCER           2016 Conquer         12/15/2015     $500,000.00
 FOUNDATION OF THE        Cancer Foundation
 AMERICAN SOCIETY OF      of the American
 CLINICAL ONCOLOGY        Society of
                          Clinical Oncology
                          Mission Endowment
------------------------------------------------------------------------
CATAMOUNT MEDICAL        PatientGPS :         12/16/2015      $74,841.86
 EDUCATION, LLC           Clinical Paths in
                          the Management of
                          Patients with
                          COPD
------------------------------------------------------------------------
AMERICAN PHARMACISTS     APhA 2016 Hot        12/16/2015      $20,000.00
 ASSOCIATION              Topics in
                          Dyslipidemia
------------------------------------------------------------------------
THE SCRIPPS RESEARCH     27th Annual          12/16/2015       $1,500.00
 INSTITUTE                Frontiers in
                          Chemistry
                          Symposium at The
                          Scripps Research
                          Institute
------------------------------------------------------------------------
NATIONAL COMPREHENSIVE   Behind the           12/17/2015      $10,000.00
 CANCER NETWORK, INC.     Guidelines:
                          Insights into the
                          Standard of Care
                          in Oncology 2016
------------------------------------------------------------------------
NATIONAL COMPREHENSIVE   NCCN 2016 Oncology   12/17/2015      $25,000.00
 CANCER NETWORK, INC.     Fellows Program:
                          New Horizons in
                          Quality Cancer
                          Care at the NCCN
                          21st Annual
                          Conference
------------------------------------------------------------------------
NATIONAL LIPID           National Lipid       12/17/2015      $30,000.00
 ASSOCIATION              Association 2016
                          Scientific
                          Meeting Series
------------------------------------------------------------------------
PEDIATRIC INFECTIOUS     Pediatric            12/20/2015      $55,000.00
 DISEASES SOCIETY         Infectious
 EDUCATION AND RESEARCH   Diseases Society
 FOUNDATION (PIDSERF)     Fellowship Awards
                          Program
------------------------------------------------------------------------
THE VANDERBILT           Cardiology 2016:     12/20/2015       $5,000.00
 UNIVERSITY               Advances in
                          Science and
                          Practice
------------------------------------------------------------------------
FOUNDATION FOR           Quality              12/22/2015      $20,000.00
 CONTINUING EDUCATION     Improvement
 IN THE HEALTH            Education (QIE)
 PROFESSIONS              Initiative
                          National Training
                          and Education
------------------------------------------------------------------------
MARYLAND SOCIETY FOR     Update on Gout and   01/04/2016       $1,625.00
 THE RHEUMATIC DISEASES   Pseudogout
------------------------------------------------------------------------
THE GOG FOUNDATION       5th Semi Annual      01/05/2016      $20,000.00
                          Meeting of NRG
                          Oncology
                          (formerly GOG,
                          NSABP,RTOG)
------------------------------------------------------------------------
CEDARS-SINAI MEDICAL     The James R.         01/05/2016       $5,000.00
 CENTER                   Klinenberg, MD
                          Symposium on
                          Rheumatic
                          Diseases: Hot
                          Topics in
                          Rheumatology
------------------------------------------------------------------------
LUNGEVITY FOUNDATION     LUNGevity            01/06/2016      $25,000.00
                          Foundation
                          Scientific and
                          Clinical Research
                          Roundtable
------------------------------------------------------------------------
CARDIOVASCULAR RESEARCH  Chronic Total        01/07/2016      $10,000.00
 FOUNDATION               Occlusion Summit
                          2016
------------------------------------------------------------------------
LUMEN FOUNDATION         Lumen Global 2016    01/10/2016      $35,000.00
------------------------------------------------------------------------
CARDIOVASCULAR RESEARCH  St. Francis          01/10/2016       $5,000.00
 FOUNDATION               Imaging Course
                          2016
------------------------------------------------------------------------
AMERICAN HEART           Epidemiology and     01/12/2016      $10,000.00
 ASSOCIATION, INC.        Prevention--Lifes
                          tyle and
                          Cardiometabolic
                          Health 2016
                          Scientific
                          Sessions
------------------------------------------------------------------------
CLEVELAND CLINIC         Beyond               01/14/2016      $22,696.65
 EDUCATIONAL FOUNDATION   Revascularization
                          for CLI-The Role
                          of
                          Pharmacotherapy
                          Satellite
                          Symposium
------------------------------------------------------------------------
CARDIOVASCULAR           CVIs 4th Annual      01/14/2016       $2,500.00
 INSTITUTE OF             Interventional
 PHILADELPHIA             Cardiovascular
                          Medicine: The
                          Crossroads of
                          Interventional
                          and Clinical
                          Cardiology
------------------------------------------------------------------------
UNIVERSITY OF TENNESSEE  Testing to Target    01/19/2016     $288,885.00
 COLLEGE OF PHARMACY      in Non-Small Cell
                          Lung Cancer:
                          Managed Care
                          Perspectives
------------------------------------------------------------------------
SOCIETY FOR VASCULAR     Society for          01/20/2016      $20,000.00
 MEDICINE                 Vascular Medicine
                          27th Annual
                          Scientific
                          Sessions
------------------------------------------------------------------------
OHIOHEALTH               1st Bi-Annual        01/20/2016       $2,500.00
                          OhioHealth Acute
                          Cardiovascular
                          Care Conference
------------------------------------------------------------------------
SOCIETY FOR              Immunotherapy of     01/24/2016      $40,000.00
 IMMUNOTHERAPY OF         Cancer for the
 CANCER                   Workshop on
                          Biomarkers
------------------------------------------------------------------------
NORTHEAST GEORGIA        8th Annual           01/25/2016       $2,500.00
 MEDICAL CENTER INC.      Northeast Georgia
                          Regional STEMI
                          Summit
------------------------------------------------------------------------
CALIFORNIA THORACIC      COPD: A TEAM         01/26/2016       $5,000.00
 SOCIETY                  APPROACH
------------------------------------------------------------------------
CARDIOVASCULAR RESEARCH  Issues with DAPT:    01/28/2016      $50,000.00
 FOUNDATION               A case-based
                          guide to optimal
                          antiplatelet
                          therapies
------------------------------------------------------------------------
GASTROINTESTINAL AND     The 2016 US GI and   01/28/2016      $16,000.00
 LIVER ASSOCIATION OF     Liver Association
 THE AMERICAS INC.        of the Americas
                          (GALA) Conference
                          Series
------------------------------------------------------------------------
GORDON RESEARCH          2016 Lipoprotein     01/28/2016       $5,000.00
 CONFERENCES              Metabolism Gordon
                          Research
                          Conference and
                          Gordon Research
                          Seminar
------------------------------------------------------------------------
AMERICAN ACADEMY OF      AAPM 32nd Annual     01/31/2016      $25,000.00
 PAIN MEDICINE            Meeting 2016
------------------------------------------------------------------------
DUKE UNIVERSITY          DCRI Evidence to     02/01/2016      $10,000.00
                          Practice Series:
                          Interventional
                          Cardiology
------------------------------------------------------------------------
AMERICAN COLLEGE OF      ACCs 65th Annual     02/01/2016      $50,000.00
 CARDIOLOGY FOUNDATION    Scientific
                          Session (ACC.16)
                          Acute Coronary
                          Syndromes
                          Clinical Learning
                          Pathway
------------------------------------------------------------------------
REGENTS OF THE           LIPID MAPS           02/01/2016       $5,000.00
 UNIVERSITY OF            Meeting:
 CALIFORNIA               Lipidomics Impact
                          on Metabolic,
                          Cancer,
                          Cardiovascular
                          and Inflammatory
                          Diseases
------------------------------------------------------------------------
SCOTTSDALE HEALTHCARE    2016 Scottsdale      02/02/2016       $2,500.00
 FOUNDATION               Interventional
                          Forum (SIF 2016)
------------------------------------------------------------------------
UNIVERSITY OF FLORIDA    Vascular Biology     02/02/2016      $15,000.00
                          Working Group
                          U.S. Chapter
                          Meeting
------------------------------------------------------------------------
EMORY UNIVERSITY         EPIC SEC Emory       02/03/2016      $20,000.00
                          Practical
                          Intervention
                          Course--Southeast
                          Consortium
------------------------------------------------------------------------
THE ENDOCRINE SOCIETY    DMS 2016:            02/07/2016     $235,318.22
                          Initiating the
                          Conversation:
                          Sharing
                          Perspectives on
                          Advances in T2DM
                          Treatment to
                          Improve Patient-
                          Centered Care
------------------------------------------------------------------------
CONQUER CANCER           2016 ASCO Annual     02/07/2016      $56,000.00
 FOUNDATION OF THE        Meeting Lung
 AMERICAN SOCIETY OF      Cancer Track
 CLINICAL ONCOLOGY
------------------------------------------------------------------------
SOCIETY FOR              SCAI 2016            02/14/2016      $25,000.00
 CARDIOVASCULAR           Scientific
 ANGIOGRAPHY AND          Sessions
 INTERVENTIONS
 FOUNDATION
------------------------------------------------------------------------
SOCIETY OF HOSPITAL      Hospital Medicine    02/14/2016      $15,000.00
 MEDICINE                 2016
------------------------------------------------------------------------
AMERICAN HEAD AND NECK   American Head and    02/17/2016      $50,000.00
 SOCIETY                  Neck Society 9th
                          International
                          Conference on
                          Head and Neck
                          Cancer
------------------------------------------------------------------------
GLOBAL EDUCATION GROUP   Clinical Issues in   02/18/2016     $411,613.00
                          Type 2 Diabetes:
                          Consensus and
                          Controversies
                          Around
                          Intensifying
                          Noninsulin
                          Therapy.
------------------------------------------------------------------------
NYU POST-GRADUATE        Seminar in           03/01/2016       $5,000.00
 MEDICAL SCHOOL           Advanced
                          Rheumatology
------------------------------------------------------------------------
NEW MEXICO THORACIC      44th Annual New      03/01/2016       $5,000.00
 SOCIETY                  Mexico Lung
                          Disease
                          Symposium--50
                          Shades of Blue
------------------------------------------------------------------------
MEDSTAR WASHINGTON       14th International   03/01/2016      $10,000.00
 HOSPITAL CENTER          Congress on
                          Targeted
                          Anticancer
                          Therapies
------------------------------------------------------------------------
FEDERATION OF AMERICAN   FASEB Conference     03/01/2016       $6,000.00
 SOCIETIES FOR            on Genome
 EXPERIMENTAL BIOLOGY     Engineering
                          Cutting-Edge
                          Research and
                          Application
------------------------------------------------------------------------
DIVISION OF MEDICINAL    Division of          03/01/2016       $2,500.00
 CHEMISTRY                Medicinal
                          Chemistry Program
                          251st ACS
                          National Meeting
------------------------------------------------------------------------
NATIONAL ASSOCIATION OF  Personalizing        03/01/2016      $35,000.00
 MANAGED CARE             Therapy for
 PHYSICIANS, INC.         Improved Patient
                          Outcomes in the
                          Management of
                          Advanced Non
                          Small-Cell Lung
                          Cancer (NSCLC)
------------------------------------------------------------------------
THE AMERICAN THORACIC    ATS 2016             03/01/2016      $20,000.00
 SOCIETY                  International
                          Conference--Selec
                          ted Topics in
                          Lung Cancer
------------------------------------------------------------------------
THE ASSOCIATION FOR      Building an          03/01/2016       $2,500.00
 FRONOTOTEMPORAL          Infrastructure to
 DEGENERATION             Support FTLD
                          Therapeutic
                          Development
------------------------------------------------------------------------
WASHINGTON ACADEMY OF    27th Annual          03/01/2016       $1,750.00
 PHYSICIAN ASSISTANTS     Recertification
                          Review Course and
                          Spring Conference
------------------------------------------------------------------------
ONCOLOGY NURSING         41st Annual          03/01/2016      $35,000.00
 SOCIETY                  Oncology Nursing
                          Society Congress
                          and Pharmacology
                          Highlights
                          regional program
------------------------------------------------------------------------
GORDON RESEARCH          Chemical             03/01/2016       $2,500.00
 CONFERENCES              Approaches for
                          Unraveling
                          Biology
------------------------------------------------------------------------
GORDON RESEARCH          Medicinal            03/01/2016       $3,000.00
 CONFERENCE               Chemistry Gordon
                          Research
                          Conference
------------------------------------------------------------------------
NATIONAL ASSOCIATION OF  2016 Charitable      03/01/2016      $30,000.00
 FREE AND CHARITABLE      Health Care
 CLINICS                  Symposium
------------------------------------------------------------------------
THE HOPE FOUNDATION      2016 SWOG Group      03/01/2016      $10,000.00
                          Meetings
------------------------------------------------------------------------
HEMATOLOGY/ONCOLOGY      2016 Hematology/     03/01/2016      $25,000.00
 PHARMACY ASSOCIATION     Oncology PHarmacy
                          Association
------------------------------------------------------------------------
MEDICAL LEARNING         New Developments     03/03/2016      $65,763.00
 INSTITUTE INC.           in the Treatment
                          of COPD: Updates
                          From San
                          Francisco
                          (150203884)
------------------------------------------------------------------------
AMERICAN                 11th Postgraduate    03/03/2016      $10,000.00
 NEUROGASTROENTEROLOGY    Course on GI
 AND MOTILITY SOCIETY     Motility and
                          Neurogastroentero
                          logy in Clinical
                          Practice
------------------------------------------------------------------------
AMERICAN ACADEMY OF      AAPA Conference      03/03/2016       $5,000.00
 PHYSICIAN ASSISTANT      2016--Allergy/
                          Immunology and
                          Pulmonology Track
------------------------------------------------------------------------
GORDON RESEARCH          Gordon Research      03/07/2016       $3,000.00
 CONFERENCE               Conference on
                          Cyclic Nucleotide
                          Phosphodiesterase
                          s: Mechanisms of
                          PDE Nano-Domain
                          Control and
                          Impacts on
                          Disease
------------------------------------------------------------------------
AMERICAN THORACIC        ATS 2016             03/07/2016      $70,000.00
 SOCIETY                  International
                          Conference--Selec
                          ted Topics in
                          COPD
------------------------------------------------------------------------
MASSACHUSETTS GENERAL    CoNNCT Workshop      03/07/2016       $2,000.00
 HOSPTIAL                 (Collaborative
                          Novel-Novel
                          Cancer Therapies)
------------------------------------------------------------------------
COLLEGIUM                31st Symposium of    03/08/2016      $10,000.00
 INTERNATIONALE           the Collegium
 ALLERGOLOGICUM           Internationale
                          Allergologicum
------------------------------------------------------------------------
NATIONAL ASSOCIATION OF  Improving Outcomes   03/08/2016      $25,000.00
 MANAGED CARE             in the Management
 PHYSICIANS               and Treatment of
                          Asthma
------------------------------------------------------------------------
NATIONAL ASSOCIATION OF  Identifying New      03/08/2016      $25,000.00
 MANAGED CARE             Strategies to
 PHYSICIANS               Optimize the
                          Management and
                          Treatment of COPD
------------------------------------------------------------------------
NORTHEASTERN SECTION OF  NESACS Advances in   03/08/2016       $1,500.00
 THE AMERICAN CHEMICAL    Chemical Sciences
 SOCIETY, INC.            Symposium
------------------------------------------------------------------------
AMERICAN THORACIC        ATS 2016             03/08/2016      $30,000.00
 SOCIETY INC.             International
                          Conference--Selec
                          ted Topics in
                          Asthma
------------------------------------------------------------------------
YALE UNIVERSITY          4th Annual Yale      03/08/2016      $15,000.00
                          COPD Symposium
------------------------------------------------------------------------
FLORIDA ALLERGY, ASTHMA  Florida Allergy,     03/14/2016      $15,000.00
 AND IMMUNOLOGY SOCIETY   Asthma and
                          Immunology
                          Society 2016
                          Annual CME
                          Conference
------------------------------------------------------------------------
UNIVERSITY OF            Keep your patients   03/14/2016      $25,000.00
 CONNECTICUT              ``moving''--An
                          Overview of
                          Treatment Options
                          for Constipation
------------------------------------------------------------------------
UHS PROFESSIONAL         32nd Annual          03/14/2016      $10,000.00
 EDUCATIONAL PROGRAMS,    Congress of
 INC.                     Clinical
                          Rheumatology
------------------------------------------------------------------------
NATIONAL KIDNEY          CKD-Related Anemia   03/17/2016     $100,050.00
 FOUNDATION               and
                          Cardiovascular
                          Risk
------------------------------------------------------------------------
UHS-PROFESSIONAL         1st Annual           03/23/2016       $5,000.00
 EDUCATION PROGRAMS       Advances in Pain
 INC.                     Care
------------------------------------------------------------------------
GORDON RESEARCH          Gordon Research      03/23/2016       $1,000.00
 CONFERENCE               Conference on
                          Cyclic Nucleotide
                          Phosphodiesterase
                          s: Mechanisms of
                          PDE Nano-Domain
                          Control and
                          Impacts on
                          Disease
------------------------------------------------------------------------
OUHSC COLLEGE OF         19th Annual          03/24/2016       $1,500.00
 MEDICINE OFFICE OF CPD   Primary Care
                          Update
------------------------------------------------------------------------
TENNESSEE ACADEMY OF     Spring Fling 2016--  03/27/2016       $3,000.00
 PHYSICIAN ASSISTANTS     Asthma and COPD
------------------------------------------------------------------------
AMERICAN THORACIC        ATS 2016             03/28/2016      $10,000.00
 SOCIETY INC.             International
                          Conference--Fello
                          w Track Symposium
------------------------------------------------------------------------
COLORADO ALLERGY AND     Biologics in the     03/29/2016       $3,000.00
 ASTHMA SOCIETY           Treatment of
                          Respiratory
                          Disease
------------------------------------------------------------------------
BOARD OF REGENTS FOR     Updates in           03/29/2016      $10,000.00
 UNIVERSITY OF NEBRASKA   Rheumatology:
                          Gout and
                          Hyperuricemia
------------------------------------------------------------------------
CANCER RESEARCH          2016 International   04/06/2016      $50,000.00
 INSTITUTE                Cancer
                          Immunotherapy
                          Conference
------------------------------------------------------------------------
AMERICAN PAIN SOCIETY    2016 Pain Care for   04/07/2016      $10,000.00
                          Primary Care
------------------------------------------------------------------------
ALZHEIMER'S ASSOCIATION  2016 Alzheimer's     04/10/2016      $50,000.00
                          Association
                          Research
                          Roundtable
------------------------------------------------------------------------
CANCER MOLECULAR         Molecular            04/10/2016       $1,500.00
 THERAPEUTICS RESEARCH    Therapeutics of
 ASSOCIATION              Cancer Conference
                          2016
------------------------------------------------------------------------
AMERICAN ASSOCIATION OF  AAPS Sustaining      04/10/2016      $50,000.00
 PHARMACEUTICAL           Sponsorship
 SCIENTISTS
------------------------------------------------------------------------
DINORA INC.              Lupus 2016           04/10/2016      $25,000.00
------------------------------------------------------------------------
INTERNATIONAL SOCIETY    American             04/10/2016       $3,000.00
 OF PHARMACOMETRICS       Conference on
                          Pharmacometrics
------------------------------------------------------------------------
HOWARD                   11th Kenneth         04/11/2016       $3,375.00
 UNIVERSITYHOSPITAL       Austin Annual
                          Rheumatology
                          Symposium
------------------------------------------------------------------------
ECOG RESEARCH AND        2016 ECOG-ACRIN      04/11/2016       $5,000.00
 EDUCATION FOUNDATION     Spring Group
                          Meeting
------------------------------------------------------------------------
AMERICAN HEART           Arteriosclerosis,    04/11/2016      $15,000.00
 ASSOCIATION, INC.        Thrombosis and
                          Vascular Biology
                          Peripheral
                          Vascular Disease
                          2016
------------------------------------------------------------------------
AMERICAN UROLOGICAL      AUA2016 Highlights   04/11/2016      $25,000.00
 ASSOCIATION EDUCATION    in Bladder Cancer
 and RESEARCH INC.
------------------------------------------------------------------------
NATIONAL KIDNEY          National Kidney      04/11/2016       $5,000.00
 FOUNDATION               Foundation s
                          Ninth Annual Mid-
                          Atlantic First
                          Year Renal
                          Fellows Symposium
------------------------------------------------------------------------
THOMAS JEFFERSON         5th Annual           04/11/2016       $3,000.00
 UNIVERSITY               Palliative Care
                          Spring Symposium
------------------------------------------------------------------------
COLUMBUS NCORP           2016 ASCO REVIEW     04/12/2016       $2,000.00
------------------------------------------------------------------------
ALZHEIMER'S ASSOCIATION  2016 Alzheimer's     04/12/2016      $45,000.00
                          Association
                          International
                          Conference
------------------------------------------------------------------------
NATIONAL COMPREHENSIVE   2016-2017 Monthly    04/12/2016      $49,008.06
 CANCER NETWORK           Oncology Tumor
                          Boards: A
                          Multidisciplinary
                          Approach to
                          Individualized
                          Patient Care
------------------------------------------------------------------------
WASHINGTON UNIVERSITY    Advances in Lung     04/13/2016       $3,000.00
                          Cancer
------------------------------------------------------------------------
TRANSLATIONAL RESEARCH   TRIO-US and UCLA     04/14/2016       $3,000.00
 IN ONCOLOGY-US, INC.     Annual Research
                          Conference
------------------------------------------------------------------------
YALE UNIVERSITY          Yale ASCO Review     04/17/2016       $2,000.00
                          2016
------------------------------------------------------------------------
SOCIETY FOR              SITC 31st Annual     04/17/2016     $300,000.00
 IMMUNOTHERAPY OF         Meeting
 CANCER
------------------------------------------------------------------------
SOCIETY FOR              2016 Primer on       04/17/2016      $50,000.00
 IMMUNOTHERAPY OF         Tumor Immunology
 CANCER                   and Cancer
                          Immunotherapy
------------------------------------------------------------------------
INTERNATIONAL            IASLC Fellowship/    04/18/2016      $43,000.00
 ASSOCIATION FOR THE      Young
 STUDY OF LUNG CANCER     Investigator
                          Award
------------------------------------------------------------------------
AMERICAN SOCIETY FOR     ASTRO 2016 58th      04/18/2016      $10,000.00
 RADIATION ONCOLOGY       Annual Meeting
------------------------------------------------------------------------
NORTHWESTERN UNIVERSITY  18th Annual Lynn     04/18/2016      $10,000.00
                          Sage Breast
                          Cancer Symposium
------------------------------------------------------------------------
AMERICAN COLLEGE OF      GAIN (EnGAiging an   04/19/2016     $500,000.00
 CHEST PHYSICIANS         Inter-
                          Disciplinary Team
                          for NSCLC
                          Diagnosis,
                          Personalized
                          Assessment, and
                          Treatment)
------------------------------------------------------------------------
AMERICAN ASSOCIATION     11th Biennial        04/21/2016      $10,000.00
 FOR CANCER RESEARCH      Ovarian Cancer
                          Research
                          Symposium
------------------------------------------------------------------------
METABOLIC ENDOCRINE      14th Annual World    04/21/2016      $75,000.00
 EDUCATION FOUNDATION     Congress on
                          Insulin
                          Resistance
                          Diabetes and
                          Cardiovascular
                          Disease--WCIRDC
------------------------------------------------------------------------
C-CHANGE                 Catalyzing Change    04/24/2016      $50,000.00
                          in Big Data and
                          Value in Cancer
                          Care
------------------------------------------------------------------------
CONQUER CANCER           2016 ASCO Pre-       04/24/2016       $5,000.00
 FOUNDATION OF THE        Annual Meeting
 AMERICAN SOCIETY OF      Seminar: How to
 CLINICAL ONCOLOGY        Integrate Tumor
                          Immunotherapy
                          into Your
                          Clinical Practice
------------------------------------------------------------------------
UNIVERSITY OF FLORIDA    Southern Salt,       04/24/2016       $3,000.00
 FOUNDATION INC.          Water, and Kidney
                          Club 57th Annual
                          Scientific
                          Meeting
------------------------------------------------------------------------
CONQUER CANCER           2016 Best of ASCO    04/24/2016      $30,000.00
 FOUNDATION OF THE        Meetings
 AMERICAN SOCIETY OF
 CLINICAL ONCOLOGY
------------------------------------------------------------------------
AMERICAN SOCIETY FOR     ASPMN 26th           04/24/2016      $15,000.00
 PAIN MANAGEMENT          National
 NURSING                  Conference
------------------------------------------------------------------------
UNIVERSITY OF TEXAS      American Society     04/24/2016       $2,000.00
 HEALTH SCIENCE CENTER    of Clinical
 AT SAN ANTONIO SOM       Oncology (ASCO)
                          2016 Review
------------------------------------------------------------------------
CLEVELAND CLINIC         ASCO Review          04/25/2016       $2,000.00
 EDUCATIONAL FOUNDATION
------------------------------------------------------------------------
DUKE UNIVERSITY          15th Annual          04/27/2016      $10,000.00
                          Southeastern
                          Fellows Research
                          Skills and
                          Training Workshop
------------------------------------------------------------------------
CEDARS-SINAI MEDICAL     2nd Annual Acing     05/02/2016       $5,000.00
 CENTER                   the GI Board
                          Exam: The
                          Ultimate High-
                          Speed Review
                          Course
------------------------------------------------------------------------
AUGUSTA UNIVERSITY       Harnessing the       05/03/2016     $220,000.00
 RESEARCH INSTITUTE,      Body's Immune
 INC.                     System to Treat
                          Cancer: the
                          Promise of
                          Immunotherapy
------------------------------------------------------------------------
AMERICAN HEART           Scientific           05/03/2016      $35,000.00
 ASSOCIATION, INC.        Sessions 2016
                          Dedicated Track
                          on Acute Coronary
                          Syndromes
------------------------------------------------------------------------
INTERNATIONAL SOCIETY    ISN Global Kidney    05/04/2016      $30,000.00
 OF NEPHROLOGY            Health Summit
------------------------------------------------------------------------
NORTHEASTERN UNIVERSITY  Boston Symposium     05/04/2016       $2,500.00
                          on Organic and
                          Bioorganic
                          Chemistry (BSOBC)
------------------------------------------------------------------------
AMERICAN ASSOCIATION     11th Biennial        05/04/2016      $15,000.00
 FOR CANCER RESEARCH      Ovarian Cancer
                          Research
                          Symposium,
------------------------------------------------------------------------
WORLD ALLERGY            WAO International    05/09/2016      $30,000.00
 ORGANIZATION             Scientific
                          Conference 2016:
                          Travel Grants
------------------------------------------------------------------------
THE GOG FOUNDATION       6th Semi Annual      05/10/2016       $5,000.00
                          Meeting of NRG
                          Oncology
                          (formerly GOG,
                          NSABP,RTOG)
------------------------------------------------------------------------
AMERICAN ASSOCIATION OF  Cardiovascular       05/10/2016       $5,000.00
 PHYSICIANS OF INDIAN     Seminar
 ORIGIN (AAPI)
------------------------------------------------------------------------
AMERICAN COLLEGE OF      Cardiovascular       05/12/2016      $20,000.00
 EMERGENCY PHYSICIANS     Disease Track at
                          ACEP 2016
                          Scientific
                          Assembly
------------------------------------------------------------------------
AMERICAN SOCIETY OF      Expanding the        05/15/2016     $190,000.00
 NEPHROLOGY               Therapeutic
                          Armamentarium for
                          Treatment of
                          Anemia of Kidney
                          Disease
------------------------------------------------------------------------
BLADDER CANCER ADVOCACY  2016 Bladder         05/15/2016      $25,000.00
 NETWORK                  Cancer Think Tank
------------------------------------------------------------------------
PREVENTIVE               2016 PCNA Fall       05/16/2016       $5,000.00
 CARDIOVASCULAR NURSES    Learning Series:
 ASSOCIATION              Diabetes and CVD:
                          Managing Patients
                          with High-Risk
                          and Co-Morbid
                          Conditions
------------------------------------------------------------------------
ASSOCIATION OF AMERICAN  2016 AACI/CCAF       05/18/2016      $10,000.00
 CANCER INSTITUTES        Annual Meeting
------------------------------------------------------------------------
UNIVERSIDAD CENTRAL DEL  Role of the          05/19/2016       $2,000.00
 CARIBE, INC.             Multidisciplinary
                          Care Team in
                          Personalizing
                          Treatment for Non-
                          Small Cell Lung
                          Cancer:
                          Addressing Tissue
                          Acquisition,
                          Diagnosis, and
                          Perso
------------------------------------------------------------------------
THE LEUKEMIA AND         2016 Waldenstrom's   05/24/2016       $3,000.00
 LYMPHOMA SOCIETY, INC.   Roadmap Symposium
------------------------------------------------------------------------
AMERICAN SOCIETY OF      ASH Scholar Award    05/25/2016      $50,000.00
 HEMATOLOGY
------------------------------------------------------------------------
AMERICAN ASSOCIATION     AACR Conference on   05/25/2016      $35,000.00
 FOR CANCER RESEARCH      Tumor Immunology
                          and Immunotherapy
------------------------------------------------------------------------
SCRIPPS HEALTH           13th Annual          05/26/2016       $2,000.00
                          Oncology Update
------------------------------------------------------------------------
DANA FARBER CANCER       International        06/02/2016      $10,000.00
 INSTITUTE                Workshop on
                          Waldenstroms
                          macroglobulinemia
                          and symposia on
                          Multiple myeloma
                          (IWWM9)
------------------------------------------------------------------------
FRIENDS OF CANCER        2016 Friends of      06/05/2016     $100,000.00
 RESEARCH                 Cancer Research
                          Programs
------------------------------------------------------------------------
PARTNERS HEALTHCARE      Massachusetts        06/08/2016       $4,771.88
 SYSTEM, INC.             General Hospital
                          Multidisciplinary
                          Breast Rounds
------------------------------------------------------------------------
VIVA PHYSICIANS, INC.    VIVA 16: Vascular    06/12/2016      $25,000.00
                          InterVentional
                          Advances
------------------------------------------------------------------------
UNIVERSITY OF COLORADO   Sex Differences      06/16/2016      $35,000.00
 DENVER, CENTER FOR       Across the
 WOMEN'S HEALTH HEALTH    Lifespan: A Focus
 RESEARCH                 on Metabolism
------------------------------------------------------------------------
THE BOARD OF REGENTS OF  Immunotherapy:       06/20/2016      $40,000.00
 THE UNIVERSITY OF        Transformation of
 NEBRASKA                 Therapies for
                          Blood Cancer a
                          satellite
                          symposium held in
                          conjunction with
                          the 2016 ASH
                          Annual Meeting
------------------------------------------------------------------------
VIVA PHYSICIANS, INC.    The Blockbuster at   06/21/2016      $69,100.00
                          VIVA 16
------------------------------------------------------------------------
AMERICAN COLLEGE OF      COPD Learning        06/22/2016      $40,000.00
 CHEST PHYSICIANS         Track
------------------------------------------------------------------------
ENDOCRINE FELLOWS        Third Annual         06/23/2016     $278,000.00
 FOUNDATION               Endocrine Fellows
                          Foundation
                          Research Meeting
------------------------------------------------------------------------
AMERICAN CANCER SOCIETY  American Cancer      06/30/2016     $163,500.00
 INC.                     Society Post-
                          Doctoral Research
                          Fellowship
                          Program
------------------------------------------------------------------------
AMERICAN COLLEGE OF      Breathing New Air    07/03/2016      $10,000.00
 OSTEOPATHIC              into the
 INTERNISTS, INC.         Treatment of COPD
                          and Asthma
------------------------------------------------------------------------
UNIVERSITY OF TEXAS      39th Annual San      07/03/2016      $75,000.00
 HEALTH SCIENCE CENTER    Antonio Breast
 AT SAN ANTONIO SCHOOL    Cancer Symposium
 OF MEDICINE--OFFICE OF
 CME
------------------------------------------------------------------------
NATIONAL JEWISH HEALTH   Evaluation and       07/04/2016      $94,011.50
                          Treatment of
                          Severe Asthma:
                          The Role of
                          Biologic and
                          Directed
                          Therapies
------------------------------------------------------------------------
NATIONAL MEDICAL         Chronic              07/04/2016     $150,000.00
 ASSOCIATION              Obstructive
                          Pulmonary Disease
                          Interdisciplinary
                          Diagnostic and
                          Treatment
                          Symposium
------------------------------------------------------------------------
GORDON RESEARCH          Gordon Research      07/10/2016       $1,440.00
 CONFERENCE               Seminar in
                          Microbial Toxins
                          and Pathogenesis
------------------------------------------------------------------------
AMERICAN ACADEMY OF      34th Annual Aspen    07/13/2016       $5,200.00
 ALLERGY, ASTHMA AND      Allergy
 IMMUNOLOGY               Conference
------------------------------------------------------------------------
GORDON RESEARCH          2016 Protein         07/13/2016       $5,000.00
 CONFERENCE               Processing
                          Trafficking and
                          Secretion
------------------------------------------------------------------------
SOCIETY FOR              New Cancer           07/14/2016      $35,000.00
 IMMUNOTHERAPY OF         Immunotherapy
 CANCER                   Agents in
                          Development
------------------------------------------------------------------------
AMINISTRATORS OF THE     16th Annual SSCI     07/14/2016      $49,939.06
 TULANE EDUCATIONAL       Nephrology Young
 FUND                     Investigators'
                          Forum
------------------------------------------------------------------------
NEW YORK ACADEMY OF      Targeting            07/18/2016      $15,000.00
 SCIENCES                 Inflammation and
                          Podocytopathy in
                          Chronic Kidney
                          Disease
------------------------------------------------------------------------
SOCIETY FOR              SITC 2016 Workshop   07/19/2016     $150,000.00
 IMMUNOTHERAPY OF         on Challenges,
 CANCER                   Insights, and
                          Future Directions
                          for Mouse and
                          Humanized Models
                          in Cancer
                          Immunology and
                          Immunotherapy
------------------------------------------------------------------------
MASSACHUSETTS GENERAL    31th Annual          07/21/2016      $10,000.00
 HOSPITAL                 Critical Issues
                          In Tumor
                          Microenvironment:
                          Angiogenesis,
                          Metastasis and
                          Immunology
------------------------------------------------------------------------
CARDIOVASCULAR RESEARCH  Transcatheter        07/21/2016      $10,000.00
 FOUNDATION               Cardiovascular
                          Therapeutics
                          (TCT) 2016
------------------------------------------------------------------------
PEPTIDE THERAPEUTICS     11th Annual          07/26/2016      $15,000.00
 FOUNDATION               Peptide
                          Therapeutics
                          Symposium
------------------------------------------------------------------------
AMERICAN SOCIETY OF      ASN Kidney Week--    07/27/2016      $20,000.00
 NEPHROLOGY               CKD Learning
                          Pathway Support
------------------------------------------------------------------------
AMERICAN ASSOCIATION     AACR DNA Repair:     07/31/2016      $25,000.00
 FOR CANCER RESEARCH      Tumor Development
                          and Therapeutic
                          Response
------------------------------------------------------------------------
NATIONAL COMPREHENSIVE   NCCN 2016 Congress   08/01/2016      $50,000.00
 CANCER NETWORK INC.      Series:
                          Immunotherapies
                          in Cancer
------------------------------------------------------------------------
CEDARS SINAI MEDICAL     Pancreatic Cancer    08/03/2016       $3,000.00
 CENTER                   Conference
------------------------------------------------------------------------
NATIONAL COMPREHENSIVE   NCCN 2016 Congress   08/04/2016      $25,000.00
 CANCER NETWORK INC.      Series: Utilizing
                          Guidelines to
                          Customize Patient
                          Care in Non-Small
                          Cell Lung Cancer
------------------------------------------------------------------------
AMERICAN COLLEGE OF      Managing Severe      08/04/2016      $12,500.00
 ALLERGY, ASTHMA AND      Asthma in Adults
 IMMUNOLOGY               and Children
                          Workshop
------------------------------------------------------------------------
ILLINOIS ACADEMY OF      Tenth Annual         08/07/2016      $54,768.91
 FAMILY PHYSICIANS        Family Medicine
                          Chief Residents
                          2016 Summit:
                          Intensifying
                          Diabetes
                          Management
------------------------------------------------------------------------
NATIONAL COMPREHENSIVE   Advanced Non-Small   08/10/2016     $100,000.00
 CANCER NETWORK, INC.     Cell Lung Cancer
                          Patient
                          Management
                          Simulator
------------------------------------------------------------------------
AMERICAN ASSOCIATION OF  AACE 2016 Balance    08/11/2016     $233,374.80
 CLINICAL                 of Evidence:
 ENDOCRINOLOGISTS         Considering the
                          Clinical Impact
                          of Newer
                          Antihyperglycemic
                          Agents for the
                          Treatment of Type
                          2 Diabetes
------------------------------------------------------------------------
HOUSTON METHODIST        4th Annual Houston   08/11/2016       $3,000.00
 HOSPITAL                 Methodist Cancer
                          Symposium
------------------------------------------------------------------------
THE AMERICAN             AASLD/EASL HBV       08/14/2016       $3,000.00
 ASSOCIATION FOR THE      Treatment
 STUDY OF LIVER           Endpoints
 DISEASES                 Workshop
------------------------------------------------------------------------
ASTHMA AND ALLERGY       Wheezin', Sneezin'   08/15/2016       $5,000.00
 FOUNDATION OF AMERICA,   and Itchin' in
 ALASKA CHAPTER           Alaska
------------------------------------------------------------------------
DANA-FARBER CANCER       Dana-Farber Cancer   08/15/2016       $2,500.00
 INSTITUTE INC.           Institute's 12 th
                          Annual
                          Postdoctoral and
                          Graduate Student
                          Retreat
------------------------------------------------------------------------
GLOBAL VIRUS NETWORK     3rd Annual Short     08/16/2016       $5,000.00
 INC.                     Course for
                          emerging leaders
                          in Medical
                          Virology of the
                          Global Virus
                          Network
------------------------------------------------------------------------
AMERICAN COLLEGE OF      Eastern Pulmonary    08/21/2016       $8,000.00
 ALLERGY, ASTHMA AND      Conference 2016
 IMMUNOLOGY
------------------------------------------------------------------------
CURATORS OF THE          2017 Midwest         08/25/2016      $35,260.00
 UNIVERSITY OF MISSOURI   Nephrology
                          Fellows Research
                          Day
------------------------------------------------------------------------
GORDON RESEARCH          Mammalian DNA        08/25/2016       $2,000.00
 CONFERENCES              Repair Gordon
                          Research
                          Conference and
                          Seminar
------------------------------------------------------------------------
NATIONAL JEWISH HEALTH   The 21st Annual      08/28/2016       $3,000.00
                          Regional Allied
                          Health
                          Conference:
                          Current
                          Perspectives in
                          Asthma, Allergy
                          and Pulmonary
                          Practice
------------------------------------------------------------------------
LUNGEVITY FOUNDATION     LUNGevity            08/28/2016      $25,000.00
                          Foundation
                          Science and
                          Clinical Research
                          Roundtable, Part
                          II
------------------------------------------------------------------------
REGENTS OF THE           14th Annual          08/29/2016      $49,509.01
 UNIVERSITY OF            Nephrology Young
 CALIFORNIA               Investigator's
                          Forum
------------------------------------------------------------------------
UNIVERSITY OF MARYLAND   18th Annual          09/01/2016       $5,000.00
 BALTIMORE FOUNDATION,    International
 INC.                     Meeting of the
                          Institute of
                          Human Virology
------------------------------------------------------------------------
INTERNATIONAL            IASLC 17th Wolrd     09/04/2016      $82,500.00
 ASSOCIATION FOR THE      Conference on
 STUDY OF LUNG CANCER     Lung Cancer--
                          International
                          Mentorship Awards
------------------------------------------------------------------------
USF HEALTH PROFESSIONS   Update in Allergy    09/07/2016       $3,000.00
 CONFERENCING             and Immunology
 CORPORATION              2016 Symposium
                          and
                          Rhinolarngoscopy
                          Hands-On Workshop
------------------------------------------------------------------------
UNIVERSITY OF NEW        Update and Review    09/07/2016       $2,500.00
 MEXICO                   of Internal
                          Medicine
------------------------------------------------------------------------
PRESIDENT AND FELLOWS    GI Motility and      09/08/2016       $1,500.00
 OF HARVARD COLLEGE       Functional GI
                          Disease: Evidence
                          vs. Consensus
------------------------------------------------------------------------
AMERICAN COLLEGE OF      ACT's 37th Annual    09/08/2016       $5,000.00
 TOXICOLOGY               Meeting
------------------------------------------------------------------------
PERSONALIZED MEDICINE    12th Annual          09/11/2016       $5,000.00
 COALITION                Personalized
                          Medicine
                          Conference
------------------------------------------------------------------------
UNIVERSITY OF SOUTHERN   1st Annual           09/13/2016       $5,000.00
 CALIFORNIA               Southern
                          California Kidney
                          Symposium:
                          ``Slowing the
                          Progression of
                          Kidney Disease:
                          From Bench to
                          Bedside''
------------------------------------------------------------------------
NATIONAL ASSOCIATION OF  Optimizing           09/21/2016      $35,000.00
 MANAGED CARE             Outcomes in
 PHYSICIANS, INC.         Advanced Non-
                          Small Cell Lung
                          Cancer (NSCLC):
                          Integrating Novel
                          Personalized
                          Therapy into the
                          Treatment
                          Paradigm
------------------------------------------------------------------------
ANNENBERG CENTER FOR     2016 JADPRO Live     09/22/2016     $100,000.00
 HEALTH SCIENCES AT       at APSHO
 EISENHOWER
------------------------------------------------------------------------
PARTNERS HEALTHCARE      Massachusetts        09/22/2016       $5,000.00
 SYSTEM, INC.             General Hospital
                          Multidisciplinary
                          Breast Rounds
                          2016-2017
------------------------------------------------------------------------
UNIVERSITY OF FLORIDA    Vascular Biology     09/22/2016       $7,800.00
                          Working Group
                          Global Chapter
                          Meeting
------------------------------------------------------------------------
JOHNS HOPKINS            Allergy Grand        09/25/2016       $2,846.55
 UNIVERSITY               Rounds
------------------------------------------------------------------------
AMERICAN ASSOCIATION     AACR-AstraZeneca     09/25/2016     $126,500.00
 FOR CANCER RESEARCH      Fellowship in
                          Ovarian Cancer
                          Research
------------------------------------------------------------------------
PHARMACY QUALITY         PQA Leadership       09/25/2016       $5,000.00
 ALLIANCE (PQA, INC.)     Summit 2016 The
                          I's Have It!
                          Insights into
                          Innovations,
                          Integration and
                          Implementation
                          Strategies for
                          Medication Use
                          Measurement
------------------------------------------------------------------------
NATIONAL COMPREHENSIVE   NCCN 2017 Congress   09/27/2016      $25,000.00
 CANCER NETWORK INC.      Series : Breast
                          Cancer with
                          Updates from the
                          2016 San Antonio
                          Breast Cancer
                          Symposium
------------------------------------------------------------------------
THE SCRIPPS RESEARCH     28th Annual          09/27/2016       $1,500.00
 INSTITUTE                Frontiers in
                          Chemistry
                          Symposium
------------------------------------------------------------------------
THE GOG FOUNDATION INC.  7th Semi Annual      09/28/2016      $20,000.00
                          Meeting of NRG
                          Oncology
                          (formerly; GOG,
                          NSABP, RTOG)
------------------------------------------------------------------------
INTERNATIONAL            Global CME program   09/28/2016      $25,000.00
 FEDERATION OF HEAD AND   of IFHNOS
 NECK ONCOLOGIC
 SOCIETIES
------------------------------------------------------------------------
PARKER INSTITUTE FOR     PICI Cancer          09/28/2016      $30,000.00
 CANCER IMMUNOTHERAPY     Immunotherapy
                          Workshops
------------------------------------------------------------------------
SOCIEDAD PUERTORRIQUE A  Endocrinology Now    10/02/2016       $5,000.00
 DE ENDOCRINOLOG A Y      and Then SPEDs
 DIABETOLOGIA             40th Anniversary
------------------------------------------------------------------------
UNIVERSITY OF TEXAS      Cancer Genetics:     10/03/2016       $5,000.00
 SOUTHWESTERN MEDICAL     Finding Meaning
 CENTER                   in Tumor and
                          Germline Genomes
------------------------------------------------------------------------
NATIONAL KIDNEY          12th Annual          10/03/2016      $50,000.00
 FOUNDATION               National Young
                          Investigator's
                          Forum
------------------------------------------------------------------------
THE UNIVERSITY OF TEXAS  The Fourth           10/05/2016       $5,000.00
 MD ANDERSON CANCER       International
 CENTER                   Conference on
                          Cancer and the
                          Heart
------------------------------------------------------------------------
AMERICAN ASSOCIATION     AACR Translational   10/05/2016      $25,000.00
 FOR CANCER RESEARCH      Control of
                          Cancer: A New
                          Frontier in
                          Cancer Biology
                          and Therapy
------------------------------------------------------------------------
METABOLIC ENDOCRINE      14th Annual World    10/05/2016      $25,000.00
 EDUCATION FOUNDATION     Congress on
                          Insulin
                          Resistance
                          Diabetes and
                          Cardiovascular
                          Disease (WCIRDC)
------------------------------------------------------------------------
CEDARS-SINAI MEDICAL     5th Annual New       10/06/2016       $5,000.00
 CENTER                   Therapeutics in
                          Oncology: The
                          Road to
                          Personalized
                          Medicine
------------------------------------------------------------------------
NATIONAL COMPREHENSIVE   Behind the           10/06/2016      $25,000.00
 CANCER NETWORK INC.      Guidelines:
                          Insights into the
                          Standard of Care
                          in Oncology 2017
------------------------------------------------------------------------
NATIONAL KIDNEY          Chronic Kidney       10/06/2016     $139,980.00
 FOUNDATION INC.          Disease and
                          Cardiovascular
                          Disease: Best
                          Practices to
                          Improve Outcomes
------------------------------------------------------------------------
ECOG RESEARCH AND        Fall 2016 ECOG-      10/09/2016       $5,000.00
 EDUCATION FOUNDATION,    ACRIN Group
 INC.                     Meeting
------------------------------------------------------------------------
INTERNATIONAL            IASLC 17th World     10/09/2016     $170,000.00
 ASSOCIATION FOR THE      Conference on
 STUDY OF LUNG CANCER     Lung Cancer
------------------------------------------------------------------------
CONQUER CANCER           2017 Conquer         10/10/2016      $40,000.00
 FOUNDATION OF THE        Cancer Foundation
 AMERICAN SOCIETY OF      of ASCO Merit
 CLINICAL ONCOLOGY        Awards
------------------------------------------------------------------------
PARTERS HEALTHCARE       Massachusetts        10/10/2016       $5,000.00
 SYSTEM, INC.             General Hospital
                          Cancer Center
                          Grand Rounds
------------------------------------------------------------------------
UNIVERSIDAD CENTRAL DEL  Redefining Cancer    10/11/2016       $5,000.00
 CARIBE, INC.             Treatment
                          Paradigms in Non-
                          Small Cell Lung
                          Cancer
------------------------------------------------------------------------
RUSH UNIVERSITY MEDICAL  Expert Insights      10/18/2016       $5,000.00
 CENTER                   and Key Nursing
                          Considerations:
                          Treating and
                          Caring for
                          Patients with
                          Lung Cancer
------------------------------------------------------------------------
GLOBAL EDUCATION GROUP   GOLD COPD:           10/18/2016      $75,000.00
                          Continuum of Care
------------------------------------------------------------------------
NATIONAL COMPREHENSIVE   NCCN 22nd Annual     10/18/2016     $100,000.00
 CANCER NETWORK           Conference:
                          Improving the
                          Quality,
                          Effectiveness,
                          and Efficiency of
                          Cancer CareTM
------------------------------------------------------------------------
SOCIETY FOR              2016 Chabner         10/19/2016      $10,000.00
 TRANSLATIONAL ONCOLOGY   Colloquium:
                          Answering the Big
                          Questions in
                          Cancer Research
------------------------------------------------------------------------
HEMATOLOGY ONCOLOGY      2017 Hematology      10/26/2016      $27,500.00
 PHARMACY ASSOCITATION    Oncology Pharmacy
                          Association q
------------------------------------------------------------------------
INTERNATIONAL            10th Biennial        10/27/2016      $10,000.00
 EOSINOPHIL SOCIETY,      Symposium
 INC.
------------------------------------------------------------------------
CONQUER CANCER           2017 ASCO-SITC       11/03/2016      $13,750.00
 FOUNDATION OF THE        Clinical Immuno-
 AMERICAN SOCIETY OF      Oncology
 CLINICAL ONCOLOGY        Symposium
                          Proceedings
------------------------------------------------------------------------
MEDSTAR GEORGETOWN       LUNG CANCER 2016:    11/03/2016       $5,000.00
 UNIVERSITY HOSPITAL      Progress and
                          Future Directions
------------------------------------------------------------------------
AMERICAN ASSOCIATION OF  18th Annual          11/03/2016      $15,000.00
 CLINICAL                 Intensive Course
 ENDOCRINOLOGISTS INC.    on Diabetes,
                          Endocrinology,
                          and Metabolic
                          Diseases
------------------------------------------------------------------------
GORDON RESEARCH          Mammalian DNA        11/03/2016       $3,000.00
 CONFERENCES              Repair Gordon
                          Research
                          Conference and
                          Seminar
------------------------------------------------------------------------
AMERICAN ASSOCIATION     AACR-AstraZeneca     11/08/2016      $73,238.00
 FOR CANCER RESEARCH      Fellowships in
                          Lung Cancer
                          Research
------------------------------------------------------------------------
PENN STATE UNIVERSITY    Cases from the       11/08/2016      $30,000.00
                          Community:
                          Investigator
                          Perspectives on
                          Emerging Research
                          and Patients with
                          Advanced Prostate
                          Cancer: A 2017 GU
                          Cancers Symposium
                          ISS
------------------------------------------------------------------------
KEYSTONE SYMPOSIA ON     Genomic              11/08/2016       $5,000.00
 MOLECULAR AND CELLULAR   Instability and
 BIOLOGY                  DNA Repair
------------------------------------------------------------------------
RENAL PHYISICIANS        RPA 2017 Annual      11/10/2016      $25,000.00
 ASSOCIATION              Meeting
------------------------------------------------------------------------
AMERICAN ASSOCIATION     AACR-AstraZeneca     11/13/2016     $253,000.00
 FOR CANCER RESEARCH      Fellowships in
                          Immuno-oncology
                          Research
------------------------------------------------------------------------
WINGATE UNIVERSITY       AmCare Pharmacy      11/21/2016         $500.00
 SCHOOL OF PHARMACY       Forum of North
                          Carolina
------------------------------------------------------------------------
SOCIETY FOR NEURO-       21st Annual          11/28/2016      $26,000.00
 ONCOLOGY                 Meeting of the
                          Society for Neuro-
                          Oncology
------------------------------------------------------------------------
LYMPHOMA RESEARCH        Lymphoma Research    12/01/2016     $105,000.00
 FOUNDATION               Foundation
                          Postdoctoral
                          Fellowship Grant
                          Program
------------------------------------------------------------------------
UNIVERSITY OF NEBRASKA   PARP Inhibition in   12/01/2016      $45,000.00
 MEDICAL CENTER           Ovarian Cancer:
                          Integrating Basic
                          Science, Clinical
                          Data, and the
                          Patient Voice to
                          Enhance Care
------------------------------------------------------------------------
KEYSTONE SYMPOSIA        2017 Keystone        12/01/2016      $25,000.00
                          Symposia
                          Directors' Fund
------------------------------------------------------------------------
BOSTON UNIVERSITY        Are You Asking the   12/04/2016     $149,275.00
 SCHOOL OF MEDICINE--     Question?
 OFFICE OF CME            Strategies for
                          Engaging the
                          Patient in the
                          Diagnosis and
                          Management of
                          Opioid-Induced
                          Constipation
------------------------------------------------------------------------
GLOBAL EDUCATION GROUP   Comprehensive Pain   12/04/2016     $324,107.00
                          Management in
                          Palliative Care:
                          Relieving the
                          Burden of Opioid-
                          Induced
                          Constipation
------------------------------------------------------------------------
CONQUER CANCER           2017 Conquer         12/04/2016     $500,000.00
 FOUNDATION OF THE        Cancer Foundation
 AMERICAN SOCIETY OF      of the American
 CLINICAL ONCOLOGY        Society of
                          Clinical Oncology
                          Mission Endowment
------------------------------------------------------------------------
AMERICAN ASSOCIATION     AACR Annual          12/04/2016     $150,000.00
 FOR CANCER RESEARCH      Meeting- 2017
------------------------------------------------------------------------
SOCIETY OF GYNECOLOGIC   Clinical             12/04/2016      $50,000.00
 ONCOLOGY                 Management of New
                          Biologics and
                          Immunotherapies
                          in Gynecologic
                          Oncology
------------------------------------------------------------------------
SOCIETY OF GYNECOLOGIC   Genetic Counseling   12/04/2016     $210,575.00
 ONCOLOGY                 in Gynecologic
                          Oncology: What
                          Advanced
                          Practitioners
                          Need to Know
------------------------------------------------------------------------
JOHNS HOPKINS DIVISION   Mid-Atlantic         12/04/2016      $50,000.00
 OF NEPHORLOGY            Nephrology Young
                          Investigators
                          Forum
------------------------------------------------------------------------
INTERNATIONAL            EGFR Atlas           12/04/2016     $380,000.00
 ASSOCIATION FOR THE
 STUDY OF LUNG CANCER
------------------------------------------------------------------------
INTERNATIONAL            2017 IASLC WCLC      12/04/2016     $150,000.00
 ASSOCIATION FOR THE      Association-
 STUDY OF LUNG CANCER     Satellite Fee
------------------------------------------------------------------------
FRIENDS OF CANCER        2017 Friends of      12/04/2016     $100,000.00
 RESERACH                 Cancer Research
                          Programs
------------------------------------------------------------------------
THE UNIVERSITY OF TEXAS  2017 Oncologic       12/06/2016       $5,000.00
 MD ANDERSON CANCER       Emergency
 CENTER                   Medicine
                          Conference
------------------------------------------------------------------------
CONQUER CANCER           2017 Genitourinary   12/08/2016      $50,000.00
 FOUNDATION OF THE        (GU) Cancers
 AMERICAN SOCIETY OF      Symposium:
 CLINICAL ONCOLOGY        Translating
                          Research to Value-
                          Based and Patient-
                          Centric Care
------------------------------------------------------------------------
ALZHEIMER'S ASSOCIATION  2017 Alzheimer's     12/08/2016      $50,000.00
                          Association
                          Research
                          Roundtable
------------------------------------------------------------------------
ALZHEIMER'S ASSOCIATION  2017 Alzheimer's     12/08/2016      $45,000.00
                          Association
                          International
                          Conference
------------------------------------------------------------------------
CANCER RESEARCH          Cancer Research      12/11/2016      $50,000.00
 INSTITUTE                Institute's
                          Irvington
                          Postdoctoral
                          Fellowship
                          Program
------------------------------------------------------------------------
CONQUER CANCER           2017 ASCO-SITC       12/11/2016      $60,000.00
 FOUNDATION OF THE        Clinical Immuno-
 AMERICAN SOCIETY OF      Oncology
 CLINICAL ONCOLOGY        Symposium
------------------------------------------------------------------------
NATIONAL COMPREHENSIVE   NCCN 11th Annual     12/12/2016      $15,000.00
 CANCER NETWORK, INC.     Congress:
                          Hematologic
                          MalignanciesTM
------------------------------------------------------------------------
INTERNATIONAL SOCIETY    ISN World Congress   12/12/2016     $130,000.00
 OF NEPHROLOGY            of Nephrology
                          2017--WCN 2017
------------------------------------------------------------------------
AMERICAN ASSOCIATION OF  AACE 26th Annual     12/12/2016      $50,000.00
 CLINICAL                 Scientific &
 ENDOCRINOLOGISTS         Clinical
                          Congress--Diabete
                          s Session
------------------------------------------------------------------------
NATIONAL KIDNEY          National Kidney      12/12/2016       $5,000.00
 FOUNDATION INC.          Foundation s
                          Tenth Annual Mid-
                          Atlantic First
                          Year Renal
                          Fellows Symposium
------------------------------------------------------------------------
THE ENDOCRINE SOCIETY    Diabetes Masters     12/13/2016      $50,000.00
                          Series 2017:
                          Negotiating the
                          Therapeutic
                          Terrain: Steps to
                          Identifying
                          Individualized
                          Treatment
                          Approaches for
                          Patients With
                          T2DM
------------------------------------------------------------------------
REGENTS OF THE           Making the           12/14/2016      $50,000.00
 UNIVERSITY OF            Connection
 CALIFORNIA               between Patients
                          and Providers: A
                          Modern Approach
                          to the Treatment
                          of Type 1 and
                          Type 2 Diabetes
------------------------------------------------------------------------
THE NEW YORK ACADEMY OF  Cancer               12/14/2016      $20,000.00
 SCIENCES                 Immunotherapy:
                          Frontiers in
                          Cancer
                          Immunotherapy and
                          Quantitative
                          Approaches in
                          Immuno-Oncology
------------------------------------------------------------------------
REGENTS OF THE           44th Annual Family   12/19/2016       $2,792.00
 UNIVERSITY OF            Medicine
 CALIFORNIA LOS ANGELES   Reffresher
                          Course"
------------------------------------------------------------------------
RUTGERS, THE STATE       Rutgers              12/19/2016      $61,728.00
 UNIVERSITY OF NEW        Pharmaceutical
 JERSEY                   Industry
                          Fellowship
                          Program
------------------------------------------------------------------------
CONQUER CANCER           2017 Conquer         12/21/2016     $192,000.00
 FOUNDATION OF THE        Cancer Foundation
 AMERICAN SOCIETY OF      of ASCO Young
 CLINICAL ONCOLOGY        Investigator
                          Award (YIA)
------------------------------------------------------------------------
NATIONAL COMPREHENSIVE   NCCN 2017 Oncology   12/21/2016      $35,000.00
 CANCER NETWORK, INC.     Fellows Program:
                          New Horizons in
                          Quality Cancer
                          Care at the NCCN
                          22nd Annual
                          Conference
------------------------------------------------------------------------
METABOLIC ENDOCRINE      1st Annual Heart     12/21/2016     $100,000.00
 EDUCATION FOUNDATION     in Diabetes
------------------------------------------------------------------------
INTERNATIONAL            IASLC 17th World     12/21/2016      $92,500.00
 ASSOCIATION FOR THE      Conference on
 STUDY OF LUNG CANCER     Lung Cancer
------------------------------------------------------------------------
PRIMARY CARE EDUCATION   11th Annual Chief    12/21/2016      $50,000.00
 CONSORTIUM               Residents Summit
                          on Intensifying
                          Diabetes
                          Management
------------------------------------------------------------------------
AMERICAN NEPHROLOGY      ANNA 2017 National   12/21/2016      $20,000.00
 NURSES ASSOCIATION       Symposium
------------------------------------------------------------------------
NATIONAL ASSOCIATION OF  2017 Charitable      12/21/2016      $30,000.00
 FREE AND CHARITABLE      Health Care
 CLINICS                  Symposium
------------------------------------------------------------------------
AMERICAN SOCIETY OF      ASN Kidney Week      12/21/2016      $37,500.00
 NEPHROLOGY               Educational
                          Session Support
------------------------------------------------------------------------
AMERICAN SOCIETY OF      ASN Kidney Week      12/21/2016      $15,000.00
 NEPHROLOGY               Early Program
                          Support
------------------------------------------------------------------------
AMERICAN SOCIETY OF      ASN Select           12/21/2016      $20,000.00
 NEPHROLOGY               Streamed Session
                          Support
------------------------------------------------------------------------
AMERICAN UROLOGICAL      Emerging             12/27/2016     $100,000.00
 ASSOCIATION EDUCATION    Immunotherapeutic
 AND RESEARCH INC.        Agents for the
                          Treatment of
                          Bladder Cancer
------------------------------------------------------------------------
AMERICAN SOCIETY OF      2016 American        01/04/2017     $150,000.00
 HEMATOLOGY               Society of
                          Hematology Annual
                          Meeting
------------------------------------------------------------------------
RUTGERS, THE STATE       Severe Asthma:       01/04/2017     $225,000.00
 UNIVERSITY OF NEW        Clinical
 JERSEY                   Phenotypes and
                          the Emerging Age
                          of Personalized
                          Therapy
------------------------------------------------------------------------
TRUSTEES OF BOSTON       A Better Life for    01/05/2017     $100,000.00
 UNIVERSITY               Your Severe
                          Asthma Patients:
                          Targeted
                          Therapies for
                          Fewer
                          Exacerbations
------------------------------------------------------------------------
NATIONAL JEWISH HEALTH   Personalized         01/06/2017     $345,500.00
                          Medicine in
                          Severe Asthma:
                          Applying Emerging
                          Data and
                          Treatments to
                          Everyday Clinical
                          Practice
------------------------------------------------------------------------
PARKER INSTITUTE FOR     Streamlining         01/18/2017      $60,000.00
 CANCER IMMUNOTHERAPY     Toxicity
                          Management
                          Guidelines
------------------------------------------------------------------------
FLORIDA ALLERGY, ASTHMA  FAAIS 2017 Annual    01/25/2017      $20,000.00
 AND IMMUNOLOGY SOCIETY   CME Conference
------------------------------------------------------------------------
NYU POST-GRADUATE        Asthma, Airways      01/26/2017      $20,000.00
 MEDICAL SCHOOL           and Environment
------------------------------------------------------------------------
NATIONAL ASSOCIATION OF  Preventing Acute     01/29/2017      $15,000.00
 MANAGED CARE             Exacerbations
 PHYSICIANS, INC.         though Novel
                          Insights in
                          Treatment
                          Strategies for
                          COPD
------------------------------------------------------------------------
NATIONAL JEWISH HEALTH   39th Annual          01/29/2017      $20,000.00
                          National Jewish
                          Health Pulmonary
                          and Allergy
                          Update
------------------------------------------------------------------------
INTERNATIONAL            Best of World        01/29/2017      $20,000.00
 ASSOCIATION FOR THE      Conference on
 STUDY OF LUNG CANCER     Lung Cancer
------------------------------------------------------------------------
YALE UNIVERSITY          Severe Asthma        02/01/2017      $16,300.00
                          2016: A
                          Personalized
                          Approach To
                          Treatment
------------------------------------------------------------------------
AMERICAN SOCIETY FOR     2017                 02/01/2017      $50,000.00
 RADIATION ONCOLOGY       Multidisciplinary
                          Thoracic Cancers
                          Symposium
------------------------------------------------------------------------
NATIONAL MEDICAL         Implementing the     02/01/2017      $75,000.00
 ASSOCCIATION             New GOLD
                          Guidelines:
                          Interdisciplinary
                          Management of
                          Chronic
                          Obstructive
                          Pulmonary Disease
                          as a Chronic
                          Disease
------------------------------------------------------------------------
CARDIOVASCULAR           Cardiovascular       02/01/2017      $25,000.00
 INNOVATIONS FOUNDATION   Innovations 2017
------------------------------------------------------------------------
AMERICAN THORACIC        ATS 2017             02/01/2017      $70,000.00
 SOCIETY INC.             International
                          Conference--Selec
                          ted Topics in
                          COPD
------------------------------------------------------------------------
CARDIOVASCULAR RESEARCH  23rd Annual          02/01/2017      $10,000.00
 FOUNDATION               Interventional
                          Cardiology
                          Fellows Course
------------------------------------------------------------------------
NATIONAL JEWISH HEALTH   13th Annual          02/01/2017     $283,830.79
                          Respiratory
                          Disease Young
                          Investigators
                          Forum
------------------------------------------------------------------------
WASHINGTON HOSPITAL      Cardiovascular       02/02/2017      $30,000.00
 CENTER CORPORATION       Research
                          Technologies
------------------------------------------------------------------------
CONNECTICUT PHARMACISTS  Breathe Easy: An     02/02/2017       $2,000.00
 ASSOCIATION              Overview of
                          Inhalers for the
                          Management of
                          Asthma and COPD
------------------------------------------------------------------------
AMERICAN ACADEMY OF      AAPA 2017--Allergy/  02/06/2017       $7,500.00
 PHYSICIAN ASSISTANTS,    Immunology and
 INC.                     Pulmonology
                          Tracks
------------------------------------------------------------------------
NATIONAL COMPREHENSIVE   Immuno-Oncology      02/07/2017      $75,000.00
 CANCER NETWORK           Therapeutics for
                          Renal Cell
                          Carcinoma and
                          Bladder Cancer:
                          Integrating the
                          Latest
                          Developments Into
                          Clinical Practice
------------------------------------------------------------------------
AMERICAN ASSOCIATION     AACR Annual          02/09/2017     $100,000.00
 FOR CANCER RESEARCH      Meeting--2017
------------------------------------------------------------------------
CONQUER CANCER           2017 Conquer         02/12/2017     $253,000.00
 FOUNDATION OF THE        Cancer Foundation
 AMERICAN SOCIETY OF      of ASCO Career
 CLINICAL ONCOLOGY        Development Award
------------------------------------------------------------------------
NYU POST-GRADUATE        NYU Seminar in       02/13/2017      $10,000.00
 MEDICAL SCHOOL           Advanced
                          Rheumatology
------------------------------------------------------------------------
THE UNIVERSITY OF TEXAS  Cardio Renal         02/14/2017       $2,500.00
 HEALTH SCIENCE CENTER    Connections--2nd
 AT SAN ANTONIO           Annual Cardio-
                          Renal Conference
                          2017
------------------------------------------------------------------------
TRUSTEES OF THE          Translational        02/14/2017       $2,500.00
 UNIVERSITY OF            Research Cancer
 PENNSYLVANIA             Centers
                          Consortium
------------------------------------------------------------------------
AMERICAN HEAD AND NECK   AHNS 2017 Annual     02/14/2017      $25,000.00
 SOCIETY                  Meeting
------------------------------------------------------------------------
GORDON RESEARCH          Gordon Research      02/15/2017       $2,500.00
 CONFERENCES              Conference on
                          Drug Metabolism
------------------------------------------------------------------------
NATIONAL JEWISH HEALTH   COPD Now: Applying   02/15/2017     $199,618.33
                          New Guidelines
                          and Effective
                          Strategies in
                          Diagnosis,
                          Treatment and
                          Management to
                          Everyday Practice
------------------------------------------------------------------------
HUMBOLDT-DEL NORTE       COPD                 02/15/2017       $2,100.00
 CONSORTIUM FOR CME
------------------------------------------------------------------------
CONQUER CANCER           2017 ASCO Annual     02/15/2017      $84,000.00
 FOUNDATION OF THE        Meeting Lung
 AMERICAN SOCIETY OF      Cancer Track
 CLINICAL ONCOLOGY
------------------------------------------------------------------------
GORDON RESEARCH          Model Systems,       02/15/2017       $5,000.00
 CONFERENCES              Emerging
                          Technologies and
                          Precision
                          Medicine in
                          Arrhythmia
                          Research and
                          Therapeutic
                          Development
------------------------------------------------------------------------
ST. JOSEPH'S REGIONAL    Acute Coronary       02/15/2017       $4,200.00
 MEDICAL CENTER           Syndrome
------------------------------------------------------------------------
AMERICAN CHEMICAL        Division of          02/16/2017       $3,000.00
 SOCIETY DIVISION OF      Medicinal
 MEDICINAL CHEMISTRY      Chemistry Program
                          253rd ACS
                          National Meeting
------------------------------------------------------------------------
SOCIETY FOR              2017 Advances in     02/16/2017     $500,000.00
 IMMUNOTHERAPY OF         Cancer
 CANCER                   Immunotherapy
                          Series
------------------------------------------------------------------------
UNIVERSITY OF FLORIDA    Vascular Biology     02/16/2017       $5,000.00
                          Working Group US
                          Chapter Meeting
------------------------------------------------------------------------
CALIFORNIA ACADEMY OF    Addressing the       02/16/2017       $3,000.00
 PHYSICIAN ASSISTANTS     Needs of the ACS
                          Patient
------------------------------------------------------------------------
CARDIOVASCULAR RESEARCH  DAPT Dilemmas: A     02/19/2017      $10,000.00
 FOUNDATION               Case-based
                          Roundtable
                          Tutorial
------------------------------------------------------------------------
INDIANA ACADEMY OF       Managing Severe      02/19/2017       $3,921.00
 FAMILY PHYSICIANS        Asthma in the
                          Family
                          Physician's
                          Office
------------------------------------------------------------------------
ANNENBERG CENTER FOR     The Emerging Role    02/19/2017     $188,600.00
 HEALTH SCIENCES AT       of Molecular
 EISENHOWER               Testing in an Era
                          of Precision
                          Medicine--NSCLC
------------------------------------------------------------------------
ANNENBERG CENTER FOR     The Emerging Role    02/19/2017     $188,600.00
 HEALTH SCIENCES AT       of Molecular
 EISENHOWER               Testing in an Era
                          of Precision
                          Medicine--Ovarian
                          Cancer
------------------------------------------------------------------------
SCRIPPS HEALTH           Scripps 37th         02/20/2017       $5,000.00
                          Annual
                          Conference:
                          Clinical
                          Hematology and
                          Oncology 2017
------------------------------------------------------------------------
AMERICAN COLLEGE OF      The Great K Debate   02/21/2017     $100,000.00
 CARDIOLOGY FOUNDATION    Continues:
                          Updates and
                          Controversies in
                          Heart Failure
                          Management
------------------------------------------------------------------------
GORDON RESEARCH          2017 Gordon          02/22/2017       $2,500.00
 CONFERENCES              Conference on
                          Medicinal
                          Chemistry
------------------------------------------------------------------------
INTERNATIONAL            17th Annual          02/22/2017      $33,000.00
 ASSOCIATION FOR THE      Targeted
 STUDY OF LUNG CANCER     Therapies of lung
                          Cancer Meeting
------------------------------------------------------------------------
AMERICAN ASSOCIATION     AACR-AHNS Head and   02/22/2017      $25,000.00
 FOR CANCER RESEARCH      Neck Cancer
                          Conference:
------------------------------------------------------------------------
ASTHMA AND ALLERGY       Wheezin', Sneezin'   02/22/2017       $5,000.00
 FOUNDATION OF AMERICA,   and Itchin' in
 ALASKA CHAPTER           Alaska
------------------------------------------------------------------------
FASEB SCIENCE RESEARCH   FASEB Autoimmunity   02/22/2017       $5,000.00
 CONFERENCES
------------------------------------------------------------------------
FEDERATION OF CLINICAL   Federation of        02/23/2017      $15,000.00
 IMMUNOLOGY SOCIETIES     Clinical
 INC.                     Immunology
                          Societies Annual
                          Meeting
------------------------------------------------------------------------
THE BOARD OF REGENTS OF  Biennial             03/02/2017      $50,000.00
 THE UNIVERSITY OF        International
 NEBRASKA                 Workshop on
                          Chronic
                          Lymphocytic
                          Leukemia (XVII
                          iwCLL 2017)
------------------------------------------------------------------------
NATIONAL KIDNEY          Change in            03/02/2017      $50,000.00
 FOUNDATION, INC.         Albuminuria and
                          GFR as End Points
                          for Clinical
                          Trials in Early
                          Stages of Chronic
                          Kidney Disease: A
                          Scientific
                          Workshop
                          Sponsored by the
                          National Kidney
                          Foundation,
                          European
                          Medicines Agency
                          and the US Food
                          and Drug
                          Administration
------------------------------------------------------------------------
AMERICAN RESPIRATORY     56th RESPIRATORY     03/05/2017      $18,000.00
 CARE FOUNDATION          CARE Journal
                          Conference
                          Respiratory
                          Medications for
                          COPD and Adult
                          Asthma:
                          Pharmacologic
                          Actions to
                          Clinical
                          Applications
------------------------------------------------------------------------
AMERICAN COLLEGE OF      ACAAI member         03/05/2017      $40,000.00
 ALLERGY, ASTHMA AND      publication--Alle
 IMMUNOLOGY               rgyWatch
------------------------------------------------------------------------
GORDON RESEARCH          The Enduring         03/05/2017       $2,500.00
 CONFERENCE               Potential of
                          Heterocycles as
                          Synthetic
                          Targets, Cellular
                          Probes, and Drug
                          Candidates
------------------------------------------------------------------------
THE REGENTS OF THE       35th Carl M.         03/06/2017      $10,000.00
 UNIVERSITY OF            Pearson Memorial
 CALIFORNIA               Symposium
                          Frontiers of
                          Rheumatology
------------------------------------------------------------------------
GORDON RESEARCH          Staphylococcal       03/06/2017       $5,000.00
 CONFERENCES--STAPHYLOC   Gordon Research
 OCCAL DISEASES           Conference
------------------------------------------------------------------------
COLD SPRING HARBOR       Cell Death           03/07/2017       $2,500.00
 LABORATORY
------------------------------------------------------------------------
CEDARS-SINAI MEDICAL     Lupus: What's        03/08/2017     $334,625.00
 CENTER                   Next? Examining
                          Mechanisms,
                          Monitoring, and
                          Medication
                          Updates
------------------------------------------------------------------------
AMERICAN THORACIC        ATS 2017 Fellows     03/09/2017      $20,000.00
 SOCIETY                  Track Symposium
------------------------------------------------------------------------
BOSTON UNIVERSITY        EFFECTIVE ASTHMA     03/11/2017     $100,000.00
 SCHOOL OF MEDICINE,      MANAGEMENT IN
 CME                      PRIMARY CARE:
                          Severity
                          Assessment,
                          Guidelines, and
                          New Therapy
                          Options
------------------------------------------------------------------------
PENNSYLVANIA STATE       Innovations in       03/12/2017       $2,500.00
 UNIVERSITY               Allergy, Asthma
                          and Immunology
                          Management
------------------------------------------------------------------------
INTERNATIONAL            IASLC SCLC           03/14/2017      $25,000.00
 ASSOCIATION FOR THE      workshop
 STUDY OF LUNG CANCER
 (IASLC)
------------------------------------------------------------------------
TRUSTEES OF BOSTON       A Better Life for    03/14/2017     $321,485.44
 UNIVERSITY               Your Severe
                          Asthma Patients:
                          Targeted
                          Therapies for
                          Fewer
                          Exacerbations
------------------------------------------------------------------------
REGENTS OF THE           Clostpath 10         03/16/2017       $5,000.00
 UNIVERSITY OF MICHIGAN   Support
------------------------------------------------------------------------
AMERICAN COLLEGE OF      Asthma Fellows       03/20/2017       $5,000.00
 CHEST PHYSICIANS         Conference
------------------------------------------------------------------------
AMERICAN COLLEGE OF      Multidisciplinary    03/20/2017      $24,354.00
 CHEST PHYSICIANS         Management Of
                          Severe Asthma: It
                          Takes A Village
------------------------------------------------------------------------
AMERICAN COLLEGE OF      Asthma Learning      03/21/2017      $79,573.00
 CHEST PHYSICIANS         Track--CHEST 2017
------------------------------------------------------------------------
AMERICAN COLLEGE OF      COPD Learning        03/22/2017      $73,765.00
 CHEST PHYSICIANS         Track
------------------------------------------------------------------------
THOMAS JEFFERSON         10th Annual Young    03/26/2017      $11,000.00
 UNIVERSITY               Investigators
                          Forum
------------------------------------------------------------------------
FLORIDA ACADEMY OF       Diagnoses and        03/27/2017       $8,000.00
 PHYSICIAN ASSISTANTS     treatment for
 INC.                     Acute coronary
                          syndrome
------------------------------------------------------------------------
SOCIETY FOR              SITC's Toxicity      03/27/2017      $50,000.00
 IMMUNOTHERAPY OF         Managment
 CANCER                   Workshop
------------------------------------------------------------------------
HOUSTON METHODIST        Cardiology for the   03/27/2017       $8,000.00
 HOSPITAL                 Non-Cardiologist
------------------------------------------------------------------------
WEST PENN ALLEGHENY      Cardiovascular       03/28/2017       $3,000.00
 HEALTH SYSTEM INC.       Medicine Update
------------------------------------------------------------------------
AMERICAN COLLEGE OF      28th Annual          03/29/2017       $5,000.00
 CARDIOLOGY PUERTO RICO   Meeting of the
 CHAPTER                  ACC Puerto Rico
                          Chapter
------------------------------------------------------------------------
HOWARD UNIVERSITY        The Kenneth Austin   03/30/2017       $2,500.00
                          12th Annual
                          Rheumatology
                          Symposium at
                          Howard University
                          Hospital
------------------------------------------------------------------------
AMERICAN RADIUM SOCIETY  99th Annual          04/02/2017      $10,000.00
                          Meeting of the
                          American Radium
                          Society
------------------------------------------------------------------------
TENNESSEE ACADEMY OF     Spring Fling 2017:   04/03/2017       $2,000.00
 PHYSICIAN ASSISTANTS     Optimizing
                          Outcomes in
                          Patients with
                          Opioid Induced
                          Constipation
------------------------------------------------------------------------
NATIONAL ASSOCIATION OF  Navigating a         04/04/2017      $35,000.00
 MANAGED CARE             Complex Treatment
 PHYSICIANS, INC.         Landscape in
                          Advanced Non-
                          Small Cell Lung
                          Cancer (NSCLC):
                          Individualizing
                          Therapy for
                          Improved Patient
                          Outcomes
------------------------------------------------------------------------
MEDICAL LEARNING         Improving the        04/06/2017     $149,000.00
 INSTITUTE INC.           Physical and
                          Mental Well-Being
                          of Patients With
                          COPD: Integrating
                          Pharmacotherapy
                          With Pulmonary
                          Rehabilitation
                          and Self-
                          Management
------------------------------------------------------------------------
AMERICAN ASSOCIATION OF  UPDATES ABOUND!      04/06/2017     $374,606.00
 CLINICAL                 Latest and
 ENDOCRINOLOGISTS INC.    Greatest in
                          Practical
                          Application of
                          Cardiovascular
                          Outcomes for
                          Diabetes Drugs
------------------------------------------------------------------------
GLOBAL EDUCATION GROUP   Overcoming           04/06/2017     $289,267.50
                          Challenges in
                          Cancer Pain
                          Management:
                          Engaging With
                          Patients About
                          Opioid-Induced
                          Constipation
------------------------------------------------------------------------
AMERICAN ASSOCIATION OF  AAPS Sustaining      04/09/2017      $50,000.00
 PHARMACEUTICAL           Sponsorship
 SCIENTISTS
------------------------------------------------------------------------
THE UNIVERSITY OF        14th International   04/10/2017      $10,000.00
 CHICAGO CENTER FOR       Ultmann Chicago
 CONTINUING MEDICAL       Lymphoma
 EDUCATION                Symposium
------------------------------------------------------------------------
AMERICAN ASSOCIATION     AACR Hematologic     04/10/2017      $25,000.00
 FOR CANCER RESEARCH      Malignancies:
------------------------------------------------------------------------
THE HOPE FOUNDATION      2017 SWOG Group      04/11/2017      $10,000.00
                          Meetings
------------------------------------------------------------------------
PREVENTIVE               2017 PCNA FAll       04/11/2017      $25,000.00
 CARDIOVASCULAR NURSES    Regional
 ASSOCIATION              Education
                          Programs:
                          Cardiometabolics:
                          Focus on New
                          Medications and
                          Risk Reduction
                          Benefits and
                          Protection
------------------------------------------------------------------------
EMORY UNIVERSITY SCHOOL  Updates in the       04/12/2017       $5,000.00
 OF MEDICINE              Management of
                          Head and Neck
                          Cancer
------------------------------------------------------------------------
NATIONAL COMPREHENSIVE   NCCN 2017 Congress   04/16/2017      $50,000.00
 CANCER NETWORK INC.      Series : Lung
                          Cancer
------------------------------------------------------------------------
ONCOLOGY NURSING         42nd Annual ONS      04/16/2017      $50,000.00
 SOCIETY                  Congress and
                          Oncology Updates
                          Regional Meetings
------------------------------------------------------------------------
SWEDISH MEDICAL CENTER   Annual Oncology      04/16/2017       $5,000.00
 FOUNDATION               Symposium:
                          Innovations in
                          Gynecologic
                          Cancer Care--
                          Prevention to
                          Survivorship
------------------------------------------------------------------------
ANNENBERG CENTER FOR     Master Class for     04/18/2017      $10,000.00
 HEALTH SCIENCES AT       Oncologists--Brea
 EISENHOWER               st Cancer Track
------------------------------------------------------------------------
ANNENBERG CENTER FOR     Master Class for     04/18/2017      $10,000.00
 HEALTH SCIENCES AT       Oncologist--Genit
 EISENHOWER               ourinary Cancers
                          Track
------------------------------------------------------------------------
ANNENBERG CENTER FOR     Oral Oncolytics      04/18/2017      $50,000.00
 HEALTH SCIENCES AT       Adherence
 EISENHOWER               Resource Center:
                          An Educational
                          Platform for
                          Advanced
                          Practitioners in
                          Oncology
------------------------------------------------------------------------
BLADDER CANCER ADVOCACY  2017 Bladder         04/18/2017      $35,000.00
 NETWORK                  Cancer Think Tank
------------------------------------------------------------------------
SOCIETY FOR              SCAI 2017            04/23/2017      $50,000.00
 CARDIOVASCULAR           Scientific
 ANGIOGRAPHY AND          Sessions
 INTERVENTIONS
------------------------------------------------------------------------
TRUSTEES OF THE          BRCA1, BRCA2 and     04/23/2017      $20,000.00
 UNIVERSITY OF            Beyond: An Update
 PENNSYLVANIA             on Hereditary
                          Cancer
------------------------------------------------------------------------
CANCER MOLECULAR         Molecular            04/24/2017       $2,000.00
 THERAPEUTICS RESEARCH    Therapeutics of
 ASSOCIATION              Cancer Research
                          Conference 2017
------------------------------------------------------------------------
YALE UNIVERSITY          2017 Lung SPORE      04/24/2017      $30,000.00
                          Workshop
------------------------------------------------------------------------
ECOG RESEARCH AND        ECOG-ACRIN Spring    04/24/2017       $5,000.00
 EDUCATION FOUNDATION,    2017 Group
 INC.                     Meeting
------------------------------------------------------------------------
CLEVELAND CLINIC         Hormone Receptor-    04/25/2017      $20,111.61
 EDUCATIONAL FOUNDATION   Positive Advanced
                          Breast Cancer:
                          Challenges and
                          New Treatment
                          Options
------------------------------------------------------------------------
INTERNATIONAL THYROID    2017 ITOG Annual     04/25/2017       $5,000.00
 ONCOLOGY GROUP           Meeting
------------------------------------------------------------------------
COLUMBIA UNIVERSITY      Breast Cancer        04/25/2017       $3,000.00
 DEPARTMENT OF SURGERY    Management 2017
------------------------------------------------------------------------
CLEVELAND CLINIC         2017 Cleveland       04/26/2017       $5,000.00
 EDUCATIONAL FOUNDATION   Breast Cancer
                          Summit:
                          Collaborating For
                          A Cure
------------------------------------------------------------------------
DUKE UNIVERSITY          16th Annual          04/27/2017      $10,000.00
                          Southeastern
                          Fellows Research
                          Skills and
                          Training Workshop
------------------------------------------------------------------------
YALE UNIVERSITY          Yale ASCO Review     05/01/2017       $5,000.00
                          2017
------------------------------------------------------------------------
MEDICAL LEARNING         Acute Management     05/02/2017     $573,560.00
 INSTITUTE INC.           of Immune-Related
                          Adverse Events in
                          Cancer Patients
                          Receiving
                          Immunotherapies:
                          Essential
                          Guidance for
                          Emergency
                          Medicine
                          Specialists
------------------------------------------------------------------------
AMERICAN COLLEGE OF      EAC 2017 Update in   05/04/2017      $10,000.00
 ALLERGY, ASTHMA AND      Allergy, Asthma
 IMMUNOLOGY               and Immunology
------------------------------------------------------------------------
METABOLIC ENDOCRINE      The Real Deal:       05/07/2017     $162,855.00
 EDUCATION FOUNDATION     Translating
                          Cardiovascular
                          Outcomes Data
                          into Best
                          Practices in Type
                          2 Diabetes
                          Management
------------------------------------------------------------------------
AMERICAN ASSOCIATION     EACR-AACR-SIC        05/08/2017      $50,000.00
 FOR CANCER RESEARCH      Special
                          Conference 2017:
                          The Challenges of
                          Optimizing Immuno-
                           and Targeted
                          Therapies
------------------------------------------------------------------------
CONQUER CANCER           2017 Best of ASCO    05/09/2017     $120,000.00
 FOUNDATION OF THE        Meetings
 AMERICAN SOCIETY OF
 CLINICAL ONCOLOGY
------------------------------------------------------------------------
REGENTS OF THE           Making the           05/10/2017     $200,000.00
 UNIVERSITY OF            Connection
 CALIFORNIA               Between Patients
                          and Providers--A
                          Modern Approach
                          to the Treatment
                          of Type 1 and
                          Type 2 Diabetes
------------------------------------------------------------------------
GORDON RESEARCH          Gordon Research      05/11/2017       $1,500.00
 CONFERENCE               Conference:
                          Hormone-Dependent
                          Cancer:
                          Functional
                          Insight and
                          Clinical
                          Application
------------------------------------------------------------------------
CARDIOVASCULAR RESEARCH  29th Annual          05/14/2017      $25,000.00
 FOUNDATION               Transcatheter
                          Cardiovascular
                          Therapeutics
------------------------------------------------------------------------
CARDIOVASCULAR RESEARCH  DAPT and Triple      05/14/2017      $10,000.00
 FOUNDATION               Therapy: A Case-
                          based Guide to
                          Optimal
                          Antiplatelet
                          Therapies
------------------------------------------------------------------------
MINNESOTA PHARMACISTS    Treating Acute       05/15/2017       $3,500.00
 ASSOCIATION              Coronary Syndrome
                          (ACS)
------------------------------------------------------------------------
ICAHN SCHOOL OF          Live Symposium of    05/15/2017       $5,000.00
 MEDICINE AT MOUNT        Complex Coronary,
 SINAI                    Valvular and
                          Vascular Cases
------------------------------------------------------------------------
AMERICAN ASSOCIATION OF  Acute Coronary       05/17/2017       $5,000.00
 CRITICAL CARE NURSES     Syndrome New
 SEPA CHAPTER             Guidelines and
                          Therapeutic
                          Options
------------------------------------------------------------------------
ANNENBERG CENTER FOR     Integration of       05/18/2017      $50,000.00
 HEALTH SCIENCES AT       Immunotherapy
 EISENHOWER               into the
                          Treatment of
                          Solid Tumors and
                          Hematologic
                          Malignancies:
                          Considerations
                          for Advanced
                          Practitioners in
                          Oncology
------------------------------------------------------------------------
ST. FRANCIS HOSPITAL     Contemporary         05/18/2017       $3,300.00
                          Dilemmas in Anti
                          Platelet Therapy
------------------------------------------------------------------------
MEMORIAL SLOAN           2017 MSK Cardio-     05/18/2017       $5,000.00
 KETTERING CANCER         Oncology
 CENTER                   Symposium:
                          Cardiovascular
                          Health and
                          Disease During
                          and After Cancer
                          Therapy--A Case
                          Based Curriculum
------------------------------------------------------------------------
GORDON RESEARCH          Gordon Research      05/18/2017       $8,000.00
 CONFERENCE               Seminar and
                          Conference on
                          Lung Development,
                          Injury and Repair
------------------------------------------------------------------------
GORDON RESEARCH          Next Generation      05/18/2017       $2,000.00
 CONFERENCES              Computer-Aided
                          Medicine Design:
                          Going Beyond
                          Traditional
                          Targets,
                          Pathways,
                          Modalities,
                          Agents and
                          Techniques
------------------------------------------------------------------------
REGENTS OF THE           13th Annual          05/19/2017       $5,000.00
 UNIVERSITY OF            Biomarkers in
 CALIFORNIA               Heart Failure and
                          Acute Coronary
                          Syndromes:
                          Diagnosis,
                          Treatment and
                          Devices Symposium
------------------------------------------------------------------------
LUNGEVITY FOUNDATION     LUNGevity            05/22/2017      $40,000.00
                          Foundation
                          Science and
                          Clinical Research
                          Roundtable
------------------------------------------------------------------------
PRESIDENT AND FELLOWS    Breast Cancer: New   05/22/2017      $20,000.00
 OF HARVARD COLLEGE       Horizons, Current
                          Controversies
------------------------------------------------------------------------
NATIONAL COMPREHENSIVE   2017-2018 Monthly    05/25/2017      $50,000.00
 CANCER NETWORK           Oncology Tumor
                          Boards: A
                          Multidisciplinary
                          Approach to
                          Individualized
                          Patient Care
------------------------------------------------------------------------
AMERICAN LUNG            LungForce Expo       05/28/2017       $1,000.00
 ASSOCIATION IN
 MISSOURI
------------------------------------------------------------------------
AMERICAN COLLEGE OF      Cardiovascular       06/03/2017     $150,000.00
 CARDIOLOGY FOUNDATION    Risk in Diabetes
------------------------------------------------------------------------
AMERICAN SOCIETY FOR     ASTRO 2017 59th      06/04/2017      $25,000.00
 RADIATION ONCOLOGY       Annual Meeting
------------------------------------------------------------------------
THE GOG FOUNDATION,      8th Semi Annual      06/04/2017      $20,000.00
 INC.                     Meeting of NRG
                          Oncology
------------------------------------------------------------------------
AMERICAN ACADEMY OF      AAFP FMX 60-minute   06/04/2017      $33,000.00
 FAMILY PHYSICIANS        Interactive
                          Lecture and 60-
                          Minute Problem-
                          Based Learning
                          Workshop titled
                          Acute Coronary
                          Syndromes
------------------------------------------------------------------------
NORTHWESTERN UNIVERSITY  6th Annual Chicago   06/04/2017      $10,000.00
                          Cardiovascular
                          Symposium
------------------------------------------------------------------------
MERCY HOSPITAL           Catholic Health      06/04/2017       $5,000.00
 FOUNDATION               8th Annual
                          Cardiovascular
                          Symposium
------------------------------------------------------------------------
AMERICAN COLLEGE OF      Lung Cancer          06/06/2017      $50,000.00
 CHEST PHYSICIANS         Learning Track
------------------------------------------------------------------------
SOCIETY FOR              2017 Primer on       06/06/2017      $50,000.00
 IMMUNOTHERAPY OF         Tumor Immunology
 CANCER                   and Cancer
                          Immunotherapy
------------------------------------------------------------------------
SOCIETY FOR              2017 Workshop on     06/07/2017     $150,000.00
 IMMUNOTHERAPY OF         Single Cell
 CANCER                   Techniques in
                          Immunology and
                          Cancer
                          Immunotherapy
------------------------------------------------------------------------
SOCIETY FOR              2018 SITC-           06/07/2017     $120,000.00
 IMMUNOTHERAPY OF         AstraZeneca
 CANCER                   Postdoctoral
                          Cancer
                          Immunotherapy in
                          Combination
                          Therapies
                          Clinical
                          Fellowship Award
------------------------------------------------------------------------
TRANSLATIONAL RESEARCH   TRIO-US AND UCLA     06/08/2017       $5,000.00
 IN ONCOLOGY-US, INC.     Annual Research
                          Conference
------------------------------------------------------------------------
ACS DIVISION OF          Division of          06/08/2017       $2,000.00
 MEDICINAL CHEMISTRY      Medicinal
                          Chemistry Program
                          254th ACS
                          National Meeting
------------------------------------------------------------------------
SAINT FRANCIS HOSPITAL   53rd Annual Robert   06/11/2017       $3,000.00
 AND MEDICAL CENTER       M. Jeresaty,
                          M.D.,
                          Cardiovascular
                          Symposium
------------------------------------------------------------------------
NYU POST-GRADUATE        Women and Cancer:    06/12/2017       $5,000.00
 MEDICAL SCHOOL           From Screening to
                          Survivorship
------------------------------------------------------------------------
PREVENTIVE               Antiplatelet         06/12/2017      $10,000.00
 CARDIOVASCULAR NURSES    Therapy Post-ACS:
 ASSOCIATION              Choosing the
                          Right Therapy for
                          the Right
                          Duration
------------------------------------------------------------------------
PERSONALIZED MEDICINE    Turning the Tide     06/13/2017      $10,000.00
 COALITION                Against Cancer
                          Through Sustained
                          Medical
                          Innovation 2017
                          National
                          Conference
------------------------------------------------------------------------
MEDICAL LEARNING         The Present and      06/13/2017     $177,230.00
 INSTITUTE                the Future of
                          Cancer
                          Immunotherapy
                          Biomarkers:
                          Assessing
                          Challenges,
                          Opportunities,
                          and Implications
                          for athologists
                          (150204581)
------------------------------------------------------------------------
AMERICAN COLLEGE OF      ACEP17               06/13/2017      $15,000.00
 EMERGENCY PHYSICIANS     Cardiovascular
                          Track
------------------------------------------------------------------------
BINAYTARA FOUNDATION     5th International    06/14/2017       $5,000.00
                          Conference on
                          Advances in
                          Hematology and
                          Oncology (ICAHO
                          2017)
------------------------------------------------------------------------
NORTHWESTERN UNIVERSITY  19th Annual Lynn     06/14/2017      $15,000.00
                          Sage Breast
                          Cancer Symposium
------------------------------------------------------------------------
AMERICAN ASSOCIATION     AACR Special         06/14/2017      $35,000.00
 FOR CANCER RESEARCH      Conference on
                          Tumor Immunology
                          and Immunotherapy
------------------------------------------------------------------------
COPD FOUNDATION INC.     COPD10USA            06/14/2017       $6,800.00
------------------------------------------------------------------------
DUKE UNIVERSITY          Duke Heart Center    06/15/2017       $5,000.00
                          General
                          Cardiology
                          Update--A Case-
                          Based Review
------------------------------------------------------------------------
AMERICAN HEART           2017 TN M:L STEMI    06/19/2017      $10,000.00
 ASSOCIATION              Conference
------------------------------------------------------------------------
THE TRANSVERSE MYELITIS  2017 Rare Neuro-     06/19/2017       $5,000.00
 ASSOCIATION              immune Disorders
                          Symposium
------------------------------------------------------------------------
INTERNATIONAL            IASLC--Lung Cancer   06/19/2017   $1,605,600.00
 ASSOCIATION FOR THE      Education
 STUDY OF LUNG CANCER
------------------------------------------------------------------------
MEDICAL LEARNING         Acute Coronary       06/20/2017     $125,000.00
 INSTITUTE INC.           Syndrome: Getting
                          to the Heart of
                          the Matter for
                          Pharmacists
------------------------------------------------------------------------
USF HEALTH PROFESSIONS   inPractice           06/21/2017      $30,000.00
 CONFERENCING             Oncology 2017-
 CORPORATION              2018: Breast and
                          Gynecologic
                          Cancers Tracks
------------------------------------------------------------------------
USF HEALTH PROFESSIONS   inPractice           06/21/2017      $20,000.00
 CONFERENCING             Oncology 2017
 CORPORATION              2018: Lung Cancer
                          Track
------------------------------------------------------------------------
GLOBAL EDUCATION GROUP,  The Role of          06/22/2017      $10,000.00
 LTD.                     Antiplatelet
                          Therapy in the
                          Short- and Long-
                          term Management
                          of Highrisk
                          Patients with ACS
------------------------------------------------------------------------
FEDERATION OF AMERICAN   FASEB Autoimmunity-  06/22/2017       $5,000.00
 SOCIETIES FOR             Additional
 EXPERIMENTAL BIOLOGY     Funding for Grant
                          #73697
------------------------------------------------------------------------
THE LEUKEMIA AND         Precision and        06/27/2017      $25,000.00
 LYMPHOMA SOCIETY, INC.   emerging Medicine
                          for Hematological
                          Diseases
------------------------------------------------------------------------
ASSOCIATION OF ASTHMA    Unraveling Current   06/27/2017      $10,000.00
 EDUCATORS                Asthma Challenges
------------------------------------------------------------------------
NATIONAL COMPREHENSIVE   NCCN 2017 Oncology   06/27/2017      $40,000.00
 CANCER NETWORK           Case Manager and
                          Medical Director
                          Program
------------------------------------------------------------------------
COPD FOUNDATION          PRAXIS and the       06/27/2017     $120,000.00
                          COPD Readmissions
                          Institute
------------------------------------------------------------------------
NATIONAL KIDNEY          New Paradigms in     06/28/2017     $158,250.00
 FOUNDATION, INC.         the Treatment of
                          Hyperkalemia
------------------------------------------------------------------------
AMERICAN ACADEMY OF      9th Allergy,         06/28/2017       $5,000.00
 PHYSICIAN ASSISTANTS     Asthma and ENT
 IN ALLERGY, ASTHMA AND   CME
 IMMUNOLOGY
------------------------------------------------------------------------
NATIONAL COMPREHENSIVE   NCCN 2017 Congress   06/29/2017      $25,000.00
 CANCER NETWORK           Series :
                          Biomarkers 101 (4
                          Live Webinars and
                          4 Enduring
                          Webinars)
------------------------------------------------------------------------
ASSOCIATION OF           Association of       06/29/2017      $10,000.00
 PHYSICIAN ASSISTANTS     Physician
 IN ONCOLOGY INC.         Assistants in
                          Oncology 20th
                          Annual Conference
------------------------------------------------------------------------
AMERICAN COLLEGE OF      TSAAI 2017 Annual    07/02/2017       $3,000.00
 ALLERGY, ASTHMA AND      Meeting
 IMMUNOLOGY
------------------------------------------------------------------------
FLORIDA ACADEMY OF       Rashes, joints and   07/02/2017       $3,000.00
 PHYSICIAN ASSISTANTS     ANA: 2017 Lupus
                          update
------------------------------------------------------------------------
WEILL CORNELL MEDICINE   Emerging             08/01/2017      $20,000.00
                          Immunological
                          Themes in
                          Oncology,
                          Metabolism and
                          Inflammation
------------------------------------------------------------------------
THE DIATRIBE FOUNDATION  Glycemic Outcomes    08/01/2017      $25,000.00
                          Beyond A1c
                          Consensus
                          Conference
------------------------------------------------------------------------
THE BOARD OF REGENTS OF  PARP Inhibitors:     08/02/2017      $90,000.00
 THE UNIVERSITY OF        Their Role in the
 NEBRASKA MEDICAL         Treatment of
 CENTER DBA UNMC CENTER   Ovarian Cancer
 FOR CONTINUING EDU
------------------------------------------------------------------------
LUNGEVITY FOUNDATION     HCP Attitudes        08/03/2017      $91,800.00
                          toward Re-biopsy
                          of Lung Cancer
                          Patients Project
------------------------------------------------------------------------
HEART FAILURE SOCIETY    Clinical Care        08/03/2017     $150,000.00
 OF AMERICA INC.          Crossroads:
                          Navigating the
                          Intersection of
                          Heart Failure and
                          Diabetes
------------------------------------------------------------------------
AMERICAN ACADEMY OF      35th Annual Aspen    08/03/2017      $10,000.00
 ALLERGY ASTHMA AND       Allergy
 IMMUNOLOGY               Conference
------------------------------------------------------------------------
BIOCONDUCTOR FOUNDATION  Bioconductor         08/03/2017       $2,000.00
 OF NA INC.               Conference 2017
------------------------------------------------------------------------
MEDICAL LEARNING         Orienteering on      08/09/2017     $795,250.00
 INSTITUTE, INC.          the Complex
                          Treatment
                          Landscape for
                          EGFR-Mutant
                          NSCLC: Latest
                          Evidence to Guide
                          Clinical
                          Decisions in
                          Everyday
                          Community
                          Practice
------------------------------------------------------------------------
THE ANGIOGENESIS         xME: Targeted        08/10/2017      $15,000.00
 FOUNDATION               Therapy,
                          Immunotherapy,
                          and the Chronic
                          Lymphocytic
                          Leukemia
                          Microenvironment
------------------------------------------------------------------------
NATIONAL COMPREHENSIVE   NCCN 12th Annual     08/21/2017      $75,000.00
 CANCER NETWORK, INC.     Congress:
                          Hematologic
                          MalignanciesT
------------------------------------------------------------------------
AMERICAN ASSOCIATION     AACR-AstraZeneca     08/21/2017     $253,000.00
 FOR CANCER RESEARCH      Fellowships in
                          Hematology-
                          Oncology Research
                          (Lymphoma)
------------------------------------------------------------------------
MEDICAL LEARNING         PeerView Master      08/21/2017     $340,120.00
 INSTITUTE, INC.          Class and
                          Practicum Live at
                          IASLC 2017 CMSTO:
                          New Options and
                          Evolving
                          Strategies for
                          Hitting the
                          Target in EGFR-
                          Mutant NSCLC
------------------------------------------------------------------------
AMERICAN SOCIETY OF      ASH Meeting on       08/22/2017      $60,000.00
 HEMATOLOGY               Hematologic
                          Malignancies
------------------------------------------------------------------------
MEDICAL LEARNING         Addressing Unmet     08/22/2017     $270,630.00
 INSTITUTE, INC.          Needs in Lung
                          Cancer With
                          Rational
                          Immunotherapy-
                          Based Approaches:
                          Evidence and
                          Practicalities
                          (150204646)
------------------------------------------------------------------------
MEDICAL LEARNING         Integrating          08/22/2017     $304,174.00
 INSTITUTE, INC.          Immunotherapy
                          into a Multimodal
                          Treatment
                          Approach
                          (150204726)
------------------------------------------------------------------------
ENDOCRINE FELLOWS        Fourth Annual        08/23/2017     $250,000.00
 FOUNDATION               Endocrine Fellows
                          Research Forum
------------------------------------------------------------------------
AMERICAN SOCIETY OF      59th ASH Annual      08/24/2017     $250,000.00
 HEMATOLOGY               Meeting
------------------------------------------------------------------------
MAYO CLINIC ARIZONA      Acute and Chronic    08/31/2017       $5,000.00
                          Leukemias 2017
------------------------------------------------------------------------
COLUMBIA UNIVERSITY      Innovations in the   08/31/2017       $1,500.00
 DEPARTMENT OF SURGERY    Management of
                          Lung Cancer:
                          Immunotherapy,
                          targeted
                          therapies and
                          minimally
                          invasive
                          techniques
------------------------------------------------------------------------
ANNEBERG CENTER FOR      JADPRO Live at       08/31/2017      $25,000.00
 HEALTH SCIENCES AT       APSHO 2017:
 EISENHOWER               Managing Side
                          Effects of Cancer
                          Patients Treated
                          With
                          Immunotherapy
------------------------------------------------------------------------
UNIVERSITY OF MARYLAND,  UPDATE: Thoracic     08/31/2017       $5,000.00
 SCHOOL OF MEDICINE       Oncology 2017
------------------------------------------------------------------------
BAYLOR COLLEGE OF        Breast Cancer        09/03/2017       $3,000.00
 MEDICINE. BREAST         Research and
 CENTER                   Education Program
------------------------------------------------------------------------
SOCIETY FOR              Grant Writing        09/03/2017      $10,000.00
 IMMUNOTHERAPY OF         Workshop
 CANCER
------------------------------------------------------------------------
COLUMBIA UNIVERSITY      2017 Gigi Shaw       09/07/2017       $3,500.00
 COLLEGE OF PHYSICIANS    Arledge
 AND SURGEONS, DEPT. OF   Conference on
 SURGERY                  Pancreatic
                          Disease
------------------------------------------------------------------------
LUPUS RESEARCH           Lupus Research       09/11/2017      $25,000.00
 ALLIANCE, INC.           Alliance 2017
                          Annual Scientific
                          Conference--Forum
                          for Discovery
------------------------------------------------------------------------
DANA FARBER CANCER       Dana-Farber Cancer   09/13/2017       $2,500.00
 INSTITUTE                Institute's 13th
                          Annual
                          Postdoctoral and
                          Graduate Student
                          Retreat
------------------------------------------------------------------------
ASSOCIATION OF           The Evolving Role    09/13/2017      $20,000.00
 COMMUNITY CANCER         of the Oncology
 CENTERS                  Pharmacist in the
                          Management of Non-
                          small Cell Lung
                          Cancer
------------------------------------------------------------------------
NATIONAL COMPREHENSIVE   Pharmacy Updates:    09/14/2017      $50,000.00
 CANCER NETWORK, INC.     A Webinar Series
------------------------------------------------------------------------
CINCINNATI CHILDREN'S    4th CURED EGID       09/18/2017       $5,000.00
                          Research
                          Conference and
                          Patient Education
                          Program
------------------------------------------------------------------------
JOHNS HOPKINS            OncologyConsults.c   09/19/2017      $10,000.00
 UNIVERSITY               om Integrating
                          Immunotherapy
                          into SCCHN Care:
                          Implications for
                          the
                          Multidisciplinary
                          Oncology Care
                          Team
------------------------------------------------------------------------
PROSTATE CANCER          24th Annual          09/19/2017      $20,000.00
 FOUNDATION               Scientific
                          Retreat
------------------------------------------------------------------------
AMERICAN PANCREATIC      48th Annual          09/19/2017      $25,000.00
 ASSOCIATION, INC.        Meeting of the
                          American
                          Pancreatic
                          Association
------------------------------------------------------------------------
MAYO CLINIC ARIZONA      Mayo Clinic Cancer   09/20/2017       $5,000.00
                          Center Thoracic
                          Oncology Update
                          State of the Art
                          Evaluation and
                          Management of
                          Thoracic Cancers
------------------------------------------------------------------------
NATIONAL COMPREHENSIVE   Behind the           09/24/2017      $25,000.00
 CANCER NETWORK           Guidelines:
 FOUNDATION (NCCN)        Insights into the
                          Standard of Care
                          in Oncology 2018
------------------------------------------------------------------------
FOUNDATION FOR HEART     21st Annual Heart    09/25/2017      $10,000.00
 FAILURE INC.             Failure 2017-An
                          Update on Therapy
------------------------------------------------------------------------
UNIVERSITY OF COLORADO/  Sex Differences      10/02/2017      $30,000.00
 CENTER FOR WOMEN'S       across the
 HEALTH RESEARCH          Lifespan: A Focus
                          on Metabolism
------------------------------------------------------------------------
LYMPHOMA RESEARCH        Adherence and Oral   10/02/2017      $20,000.00
 FOUNDATION               Therapies in
                          Lymphoma and CLL
                          Workshop
------------------------------------------------------------------------
ECOG RESEARCH AND        ECOG-ACRIN 2017      10/02/2017      $15,000.00
 EDUCATION FOUNDATION,    Fall Group
 INC.                     Meeting
------------------------------------------------------------------------
SOCIETY FOR              SCAI 2017            10/02/2017      $35,000.00
 CARDIOVASCULAR           Interventional
 ANGIOGRAPHY AND          Cardiology
 INTERVENTIONS            Fellows Course
 FOUNDATION
------------------------------------------------------------------------
THE UNIVERSITY OF TEXAS  Emerging Therapies   10/04/2017       $5,000.00
 MD ANDERSON CANCER       in Oncology From
 CENTER                   Phase I and
                          Beyond
------------------------------------------------------------------------
INTERNATIONAL            Best of 18th World   10/05/2017      $20,000.00
 ASSOCIATION FOR THE      Conference on
 STUDY OF LUNG CANCER     Lung Cancer
                          (WCLC)
------------------------------------------------------------------------
AMERICAN UROLOGICAL      Assessing the        10/09/2017      $75,000.00
 ASSOCIATION              Educational Needs
                          of Urologic Care
                          Team in the area
                          of Bladder Cancer
                          and Immunotherapy
------------------------------------------------------------------------
COLORADO ALLERGY AND     CAAS October 2017    10/09/2017       $3,343.10
 ASTHMA SOCIETY           ``State of the
                          Art Approaches to
                          Asthma Diagnosis
                          and Treatment''
------------------------------------------------------------------------
ICAHN SCHOOL OF          Top Ten Advances     10/12/2017       $5,000.00
 MEDICINE AT MOUNT        in Clinical
 SINAI                    Cardiology
------------------------------------------------------------------------
THE MASSACHUSETTS        Boston               10/12/2017       $4,000.00
 GENERAL HOSPITAL         Angiogenesis
                          Meeting
------------------------------------------------------------------------
AMERICAN SOCIETY OF      Anemia in Kidney     10/16/2017     $155,550.00
 NEPHROLOGY               Diseases: Beyond
                          the Usual
                          Suspects
------------------------------------------------------------------------
REGENTS OF THE           Updates in           10/16/2017       $5,000.00
 UNIVERSITY OF            Rheumatology
 CALIFORNIA, UCSD         2017: Highlights
 OFFICE OF CME            from the ACR and
                          EULAR Meetings
------------------------------------------------------------------------
FLORIDA ACADEMY OF       Acute Coronary       10/16/2017       $7,500.00
 PHYSICIAN ASSISTANTS     Syndrome
------------------------------------------------------------------------
NEBRASKA ACADEMY OF      Acute Coronary       10/16/2017       $7,500.00
 PHYSICIAN ASSISTANTS     Syndrome: A
                          Review of
                          Diagnostic
                          Criteria, and
                          Treatment Options
------------------------------------------------------------------------
PEPTIDE THERAPEUTICS     12th Annual          10/18/2017      $15,000.00
 FOUNDATION               Peptide
                          Therapeutics
                          Symposium
------------------------------------------------------------------------
KEYSTONE SYMPOSIA ON     Cancer               10/18/2017      $15,000.00
 MOLECULAR AND CELLULAR   Immunotherapy:
 BIOLOGY                  Combinations
------------------------------------------------------------------------
THE PENNSYLVANIA STATE   Beyond the           10/24/2017      $30,000.00
 UNIVERSITY               Guidelines:
                          Investigator
                          Perspectives on
                          Current Clinical
                          Issues and
                          Ongoing Research
                          in the Management
                          of Advanced
                          Prostate Cancer--
                          An ISS Held as a
                          Premium Ancillary
                          Educational Event
                          During the 2018
                          Genitourinary
                          Cancers Symposium
------------------------------------------------------------------------
TRUSTEES OF TUFTS        2017 Tufts Cancer    10/26/2017       $2,500.00
 COLLEGE                  Symposium,
                          Transforming
                          Therapeutic
                          Outcomes:
                          Innovations in
                          Cancer Modeling
------------------------------------------------------------------------
MEDSTAR GEORGETOWN       Lung Cancer 2017:    10/26/2017       $7,500.00
 MEDICAL CENTER INC.      Progress and
                          Future Directions
------------------------------------------------------------------------
AMERICAN COLLEGE OF      American College     10/29/2017       $5,000.00
 TOXICOLOGY               of Toxicology
                          38th Annual
                          Meeting,
                          Symposium 6:
                          Early Career
                          Professionals'
                          Forum: Current
                          Topics in
                          Toxicology
------------------------------------------------------------------------
SOCIETY FOR              SITC's connectED     11/01/2017     $500,000.00
 IMMUNOTHERAPY OF
 CANCER
------------------------------------------------------------------------
THE BOARD OF TRUSTREES   Stanford Review of   11/06/2017       $5,000.00
 OF THE LELAND STANFORD   the 59th Annual
 JUNIOR UNIVERSITY        American Society
                          of Hematology
                          Meeting 2018
------------------------------------------------------------------------
UNIVERSITY OF            Rheumatology         11/07/2017      $15,000.00
 CINCINNATI               Winter Clinical
                          Symposium 2018
                          (RWCS 2018)
------------------------------------------------------------------------
UT HEALTH SAN ANTONIO    40TH Annual San      11/07/2017      $75,000.00
 (UTHSCSA)                Antonio Breast
                          Cancer Symposium
------------------------------------------------------------------------
THE GOG FOUNDATION INC.  9th Semi Annual      11/08/2017      $20,000.00
                          Meeting of NRG
                          Oncology
------------------------------------------------------------------------
NATIONAL COMPREHENSIVE   NCCN AACR ASCO       11/08/2017     $710,115.00
 CANCER NETWORK, INC.     Stage III NSCLC
                          Practical
                          Application of
                          Immune Checkpoint
                          Inhibition After
                          Chemoradiotherapy
------------------------------------------------------------------------
CANCER RESEARCH          CRI Irvington        11/08/2017      $50,000.00
 INSTITUTE                Postdoctoral
                          Fellowship
                          Program
------------------------------------------------------------------------
MID-ATLANTIC SECTION OF  2017 Society for     11/09/2017      $10,000.00
 THE AMERICAN             Basic Urologic
 UROLOGICAL ASSOCIATION   Research (SBUR)
                          and European
                          Society for
                          Urological
                          Research (ESUR)
                          joint Fall
                          Symposium
------------------------------------------------------------------------
WEST PENN ALLEGHENY      Twelfth Annual       11/09/2017       $8,000.00
 HEALTH SYSTEM DBA        Nemacolin
 ALLEGHENY GENERAL        International
 HOSPITAL                 Asthma Conference
                          An Interactive
                          Forum on Patient
                          Care, Therapy,
                          and Research
------------------------------------------------------------------------
UNIVERSITY OF            Request for 2017     11/14/2017       $5,000.00
 CALIFORNIA BERKELEY      Funding for the
 FOUNDATION               Forum for
                          Collaborative
                          Research's
                          Program on HBV
------------------------------------------------------------------------
AMERICAN SOCIETY FOR     2018                 11/14/2017      $35,000.00
 RADIATION ONCOLOGY       Multidisciplinary
 (ASTRO)                  Head and Neck
                          Cancer Symposium:
                          Expanding
                          Treatment
                          Horizons
------------------------------------------------------------------------
AMERICAN SOCIETY OF      Hematology 2017:     11/15/2017      $75,000.00
 HEMATOLOGY               the ASH Education
                          Program
------------------------------------------------------------------------
THE UNIVERSITY OF TEXAS  Leukemia Research    11/15/2017       $5,000.00
 MD ANDERSON CANCER       Meeting
 CENTER
------------------------------------------------------------------------
AMERICAN SOCIETY OF      2018 Highlights of   11/15/2017     $100,000.00
 HEMATOLOGY               ASHr in North
                          America
------------------------------------------------------------------------
CONQUER CANCER           2018 Conquer         11/16/2017      $40,000.00
 FOUNDATION OF THE        Cancer Foundation
 AMERICAN SOCIETY OF      of ASCO Merit
 CLINICAL ONCOLOGY        Awards
------------------------------------------------------------------------
CONQUER CANCER           2018 ASCO-SITC       11/21/2017      $60,000.00
 FOUNDATION OF THE        Clinical Immuno-
 AMERICAN SOCIETY OF      Oncology
 CLINICAL ONCOLOGY        Symposium
------------------------------------------------------------------------
AMERICAN COLLEGE OF      New York             11/21/2017       $5,000.00
 CARDIOLOGY FOUNDATION    Cardiovascular
                          Symposium
------------------------------------------------------------------------
NATIONAL KIDNEY          Scientific           11/22/2017     $160,000.00
 FOUNDATION INC.          Workshop on
                          Change in
                          Albuminuria and
                          GFR as End Points
                          for Clinical
                          Trials in Early
                          Stages of Chronic
                          Kidney Disease
------------------------------------------------------------------------
MEDICAL LEARNING         PeerView             11/27/2017      $50,000.00
 INSTITUTE, INC.          MasterClass--Prac
                          ticum Live at
                          ASCO GI The Quest
                          to Win Through
                          Science in
                          Pancreatic Cancer
                          From Sequencing
                          Current Options
                          to Testing Novel
                          Approaches
------------------------------------------------------------------------
THE GUTHY JACKSON        ECTRIMS 2017 NMO     11/29/2017       $6,000.00
 CHARITABLE FOUNDATION    Symposium
------------------------------------------------------------------------
AALAS FOUNDATION         Student and          11/30/2017       $5,000.00
                          Teacher Public
                          Educational
                          Outreach
------------------------------------------------------------------------
GORDON RESEARCH          Biology of Acute     12/01/2017       $5,000.00
 CONFERENCE               Respiratory
                          Infection Gordon
                          Research
                          Conference
------------------------------------------------------------------------
LEUKEMIA RESEARCH        Hollis Brownstein    12/03/2017     $100,000.00
 FOUNDATION               Research Grants
                          Program
------------------------------------------------------------------------
AMERICAN COLLEGE OF      2017 ACR/ARHP        12/03/2017      $75,000.00
 RHEUMATOLOGY             Annual Meeting
                          Lupus Educational
                          Track
------------------------------------------------------------------------
NATIONAL JEWISH HEALTH   40th Annual          12/04/2017      $20,000.00
                          National Jewish
                          Health Pulmonary
                          and Allergy
                          Update
------------------------------------------------------------------------
KEYSTONE SYMPOSIA ON     2018 Keystone        12/04/2017      $25,000.00
 MOLECULAR AND CELLULAR   Symposia
 BIOLOGY                  Directors' Fund
------------------------------------------------------------------------
AMERICAN DIABETES        Diabetes is          12/04/2017      $40,568.50
 ASSOCIATION              Primary Digital
                          Program on
                          Cardiovascular
                          Risk
------------------------------------------------------------------------
AMERICAN COLLEGE OF      2017 ACLAM Grants    12/04/2017       $4,000.00
 LABORATORY ANIMAL
 MEDICINE
------------------------------------------------------------------------
SOUTHERN MEDICAL         Medical Dilemmas     12/05/2017       $2,500.00
 ASSOCIATION              in Patient Care
                          Conference
------------------------------------------------------------------------
THE NORTH AMERICAN 3RS   Virtual Education    12/06/2017       $8,000.00
 COLLABORATIVE            Community Support
------------------------------------------------------------------------
CONQUER CANCER           2018 Conquer         12/10/2017     $500,000.00
 FOUNDATION OF THE        Cancer Foundation
 AMERICAN SOCIETY OF      of ASCO Mission
 CLINICAL ONCOLOGY        Endowment
------------------------------------------------------------------------
CONQUER CANCER           2018 Genitourinary   12/10/2017      $60,000.00
 FOUNDATION OF THE        (GU) Cancers
 AMERICAN SOCIETY OF      Symposium:
 CLINICAL ONCOLOGY        Translating
                          Evidence to
                          Multidisciplinary
                          Care
------------------------------------------------------------------------
CONQUER CANCER           2018 Conquer         12/10/2017     $256,000.00
 FOUNDATION OF THE        Cancer Foundation
 AMERICAN SOCIETY OF      of ASCO Young
 CLINICAL ONCOLOGY        Investigator
                          Award (YIA)
------------------------------------------------------------------------
REGENTS OF THE           15th Annual          12/10/2017      $40,000.00
 UNIVERSITY OF            Nephrology Young
 CALIFORNIA               Investigators
                          Forum
------------------------------------------------------------------------
JOHNS HOPKINS            Mid Atlantic         12/10/2017      $50,000.00
 UNIVERSITY SCHOOL OF     Nephrology Young
 MEDICINE                 Investigators
                          Forum
------------------------------------------------------------------------
ILLINOIS ACADEMY OF      The 12th Annual      12/11/2017      $54,771.32
 FAMILY PHYSICIANS        Chief Residents
                          Summit on
                          Intensifying
                          Diabetes
                          Management
------------------------------------------------------------------------
AMERICAN COLLEGE OF      2018 ACR             12/11/2017      $50,000.00
 RHEUMATOLOGY             Rheumatology
                          Courses
------------------------------------------------------------------------
JOHNS HOPKINS            FastForward          12/12/2017      $25,000.00
 UNIVERSITY               Corporate
                          Sponsorship
------------------------------------------------------------------------
THE DEUEL CONFERENCE ON  The 2018 Deuel       12/13/2017       $5,000.00
 LIPIDS                   Conference on
                          Lipids
------------------------------------------------------------------------
FEDERATION OF AMERICAN   FASEB SRC            12/13/2017       $5,000.00
 SOCIETIES FOR            Immunoreceptors
 EXPERIMENTAL BIOLOGY     and Immunotrerapy
 (FASEB)
------------------------------------------------------------------------
UNIVERSITY OF            Request for 2018     12/13/2017      $10,000.00
 CALIFORNIA BERKELEY      Funding for the
 FOUNDATION               Forum for
                          Collaborative
                          Research's
------------------------------------------------------------------------
GORDON RESEARCH          Gordon Conference    12/14/2017       $5,000.00
 CONFERENCE               on Drug
                          Resistance 2018
------------------------------------------------------------------------
ASSOCIATION FOR WOMEN    Innovation and       12/17/2017      $25,000.00
 IN SCIENCE               Inclusion: Women
                          at the Forefront
                          of STEM
------------------------------------------------------------------------
VIRGINIA BIOTECHNOLOGY   MedImmune            12/17/2017      $25,000.00
 ASSOCIATION              Chairman's Circle
                          Membership
------------------------------------------------------------------------
FEDERATION OF AMERICAN   The Lung             12/20/2017       $5,000.00
 SOCIETIES FOR            Epithelium in
 EXPERIMENTAL BIOLOGY     Health and
 SRC                      Disease
------------------------------------------------------------------------
ENGINEERING CONFERENCES  Cell Culture         12/21/2017      $10,000.00
 INTERNATIONAL            Engineering XVI
                          Conference
------------------------------------------------------------------------
PENNYSLVANIA SOCIETY     2018 PSBR            12/24/2017       $2,000.00
 FOR BIOMEDICAL           Membership
 RESEARCH
------------------------------------------------------------------------
NATIONAL ACADEMY OF      Roundtable in        12/24/2017       $4,000.00
 SCIENCES                 Science and
                          Welfare of
                          Laboratory Animal
                          Use
------------------------------------------------------------------------
CONQUER CANCER           2018                 01/02/2018      $30,000.00
 FOUNDATION OF THE        Gastrointestinal
 AMERICAN SOCIETY OF      (GI) Cancers
 CLINICAL ONCOLOGY        Symposium:
                          Multidisciplinary
                          Care: Local
                          Practice, Global
                          Outcomes
------------------------------------------------------------------------
AMERICAN ASSOCIATION     AACR-IASLC Joint     01/02/2018      $25,000.00
 FOR CANCER RESEARCH      Conference on the
                          Molecular Origins
                          of Lung Cancer
------------------------------------------------------------------------
NATIONAL JEWISH HEALTH   14th Annual          01/02/2018     $299,608.49
                          Respiratory
                          Disease Young
                          Investigators'
                          Forum
------------------------------------------------------------------------
THE CHEST FOUNDATION     CHEST Foundation     01/02/2018      $55,000.00
                          Research Award in
                          COPD
------------------------------------------------------------------------
INTERNATIONAL            Implementation of    01/04/2018     $300,000.00
 ASSOCIATION FOR THE      diagnostic and
 STUDY OF LUNG CANCER     molecular
                          guidelines in low-
                          middle income
                          regions for
                          targeted
                          therapies in
                          NSCLC
------------------------------------------------------------------------
UNIVERSITY OF NORTH      9th International    01/09/2018       $2,500.00
 CAROLINA AT CHAPEL       Symposia for the
 HILL                     CGRP Family
                          Peptides
                          Conference
------------------------------------------------------------------------
UNIVERSITY OF            The Intersection     01/14/2018      $95,000.00
 CINCINNATI               Between COPD and
                          Cardiometabolic
                          Comorbidities
------------------------------------------------------------------------
NATIONAL KIDNEY          13th Annual          01/14/2018      $50,000.00
 FOUNDATION INC.          National Young
                          Investigator
                          Forum
------------------------------------------------------------------------
AMERICAN COLLEGE OF      WSAAI 2018: 56th     01/17/2018      $15,000.00
 ALLERGY, ASTHMA AND      Annual Scientific
 IMMUNOLOGY (ACAAI)       Session
------------------------------------------------------------------------
AMERICAN ASSOCIATION     AACR-SNMMI Joint     01/18/2018      $10,000.00
 FOR CANCER RESEARCH      Conference on
                          State-of-the-Art
                          Molecular Imaging
                          in Cancer Biology
                          and Therapy
------------------------------------------------------------------------
THE UNIVERSITY OF TEXAS  2018 Oncologic       01/23/2018      $10,000.00
 MD ANDERSON CANCER       Emergency
 CENTER                   Medicine
                          Conference
------------------------------------------------------------------------
NATIONAL ASSOCIATION OF  Exploring the        01/25/2018      $35,000.00
 MANAGED CARE             Challenges of
 PHYSICIANS               Severe Asthma:
                          Understanding
                          Appropriate
                          Treatment
                          Strategies for
                          Improved Patient
                          Outcomes
------------------------------------------------------------------------
CANCER RESEARCH          Cancer               02/05/2018      $10,000.00
 INSTITUTE                Immunotherapy
                          Consortium
                          Workshop
------------------------------------------------------------------------
ANNENBERG CENTER FOR     Advancing            02/11/2018     $200,000.00
 HEALTH SCIENCES AT       Knowledge to
 EISENHOWER               Practice
                          Optimizing Severe
                          Asthma Care in
                          the Age of
                          Biologics
------------------------------------------------------------------------
PENNSYLVANIA STATE       PeerView Live at     02/12/2018     $104,507.00
 UNIVERSITY               the 2018 ASCO
                          Annual Meeting,
                          The Arrival of
                          Novel Agent
                          Classes in B-Cell
                          Non-Hodgkin
                          Lymphoma: A
                          Personal Guide to
                          Integrating New
                          Therapy into
                          Patient Care
                          (150204877)
------------------------------------------------------------------------
ANNENBERG CENTER FOR     Clinical Advances    02/13/2018      $75,000.00
 HEALTH SCIENCES          and Case Studies
                          in Immune
                          Checkpoint
                          Inhibitors in
                          Oncology
------------------------------------------------------------------------
NATIONAL COMPREHENSIVE   NCCN 2018 Oncology   02/14/2018      $35,000.00
 CANCER NETWORK, INC.     Fellows Program:
                          New Horizons in
                          Quality Cancer
                          CareT at the NCCN
                          23rd Annual
                          Conference
------------------------------------------------------------------------
INDY HEMATOLOGY          2018 Indy            02/14/2018      $10,000.00
 EDUCATION, INC.          Hematology Review
------------------------------------------------------------------------
JOHNS HOPKINS            14th International   02/14/2018      $20,000.00
 UNIVERSITY               Symposium on
                          Sjogrens Syndrome
------------------------------------------------------------------------
SCRIPPS HEALTH           Scripps 38th         02/14/2018      $25,000.00
                          Annual Clinical
                          Hematology and
                          Oncology
                          Conference
------------------------------------------------------------------------
THE CHEST FOUNDATION     CHEST Foundation     02/14/2018      $35,000.00
                          Research Award in
                          Severe Asthma
------------------------------------------------------------------------
ANNENBERG CENTER FOR     Clinical             02/14/2018     $100,000.00
 HEALTH SCIENCES          Management of
                          Novel Therapies
                          for Hematological
                          Malignancies (5
                          Regional lectures
                          by APSHO/JADPRO)
------------------------------------------------------------------------
MEDICAL LEARNING         PeerView inVision,   02/14/2018      $64,125.00
 INSTITUTE, INC.          ``Targeted
                          Treatment in
                          Severe Asthma:
                          Moving Toward
                          Precision
                          Medicine''
------------------------------------------------------------------------
COLLEGIUM                32nd Symposium of    02/14/2018      $10,000.00
 INTERNATIONALE           the Collegium
 ALLERGOLOGICUM           Internationale
                          Allergologicum
------------------------------------------------------------------------
AMERICAN SOCIETY FOR     Immuno-Oncology:     02/14/2018      $60,490.00
 CLINICAL PATHOLOGY       Scientific
                          Updates
------------------------------------------------------------------------
NATIONAL JEWISH HEALTH   COPD Basics: An      02/14/2018     $100,000.00
                          Integrated
                          Approach to Best
                          Practices in Five
                          Healthcare
                          Networks
------------------------------------------------------------------------
MAYO CLINIC ARIZONA      Clinical             02/14/2018      $15,000.00
                          Multidisciplinary
                          Hematology and
                          Oncology: The
                          15th Annual
                          Review
------------------------------------------------------------------------
INTERNATIONAL            18th Targeted        02/14/2018      $55,100.00
 ASSOCIATION FOR THE      Therapy meeting
 STUDY OF LUNG CACEER
------------------------------------------------------------------------
MEDICAL LEARNING         PeerView Master      02/14/2018     $299,330.00
 INSTITUTE, INC.          Class and
                          Practicum Live at
                          CHEST 2018, ``New
                          Avenues in Asthma
                          Management:
                          Finding the Right
                          Patients for
                          Targeted
                          Therapies''
                          (150205033)
------------------------------------------------------------------------
NATIONAL KIDNEY          Chronic              02/15/2018     $232,979.00
 FOUNDATION INC.          Hyperkalemia
                          Management and
                          Outcomes in CKD
------------------------------------------------------------------------
ALZHEIMER'S ASSOCIATION  Alzheimer's          02/15/2018      $45,000.00
                          Association
                          International
                          Conference, AAIC
                          2018
------------------------------------------------------------------------
ASTHMA AND ALLERGY       Wheezin', Sneezin'   02/16/2018      $10,000.00
 FOUNDATION OF AMERICA--  and Itchin' in
 ALASKA CHAPTER           Alaska
------------------------------------------------------------------------
NATIONAL ASSOCIATION OF  New Agents and       02/18/2018      $35,000.00
 MANAGED CARE             Emerging
 PHYSICIANS               Strategies in
                          Advanced Breast
                          Cancer: Patient-
                          Centric
                          Navigation in the
                          Age of
                          Personalized Care
------------------------------------------------------------------------
THE PENNSYLVANIA STATE   PeerView inPlay,     02/18/2018     $145,730.00
 UNIVERSITY               ``The Role of the
                          Eosinophil in
                          COPD:
                          Implications for
                          Personalized Care
                          and Novel
                          Treatments''
                          (150205058)
------------------------------------------------------------------------
DUKE UNIVERSITY          3rd Annual Duke      02/19/2018       $2,500.00
                          Heart Center/DCRI
                          Fellows'
                          Presentation
                          Skills Course
------------------------------------------------------------------------
NATIONAL ASSOCIATION OF  Novel Treatment      02/19/2018      $35,000.00
 MANAGED CARE             Strategies in the
 PHYSICIANS, INC.         Management of
                          Ovarian Cancer: A
                          Closer Look at
                          the Role of PARP
                          Inhibitors
------------------------------------------------------------------------
AMERICAN THORACIC        ATS 2018 Fellows     02/19/2018      $10,000.00
 SOCIETY INC.             Track Symposium
------------------------------------------------------------------------
MEDSTAR WASHINGTON       Cardiovascular       02/20/2018      $30,000.00
 HOSPITAL CENTER          Research
                          Technologies
                          (CRT) Annual
                          Meeting
------------------------------------------------------------------------
DUKE UNIVERSITY          The Southeastern     02/21/2018       $2,500.00
                          Fellows Research
                          Skills and
                          Training Workshop
------------------------------------------------------------------------
AMERICAN THORACIC        ATS 2018             02/21/2018      $30,000.00
 SOCIETY INC.             International
                          Conference--Selec
                          ted Sessions in
                          COPD
------------------------------------------------------------------------
SCRIPPS HEALTH           15th Annual          02/22/2018      $25,000.00
                          Fundamentals of
                          Diabetes
                          Management
------------------------------------------------------------------------
AMERICAN ASSOCIATION     FDA-AACR-ASTRO:      02/22/2018      $25,000.00
 FOR CANCER RESEARCH      Clinical
                          Development of
                          Drug-Radiotherapy
                          Combinations
                          Workshop
------------------------------------------------------------------------
AMERICAN ASSOCIATION     Advances in          02/25/2018      $25,000.00
 FOR CANCER RESEARCH      Malignant
                          Lymphoma (AACR/
                          ICML ``off year''
                          conference in US)
------------------------------------------------------------------------
BLADDER CANCER ADVOCACY  2018 Bladder         02/25/2018      $35,000.00
 NETWORK                  Cancer Think Tank
------------------------------------------------------------------------
GORDON RESEARCH          2018 Gordon          02/27/2018       $5,000.00
 CONFERENCE               Research Council
                          on New Antibiotic
                          Discovery and
                          Development
------------------------------------------------------------------------
RUTGERS, THE STATE       Treat-to-Target      02/28/2018     $124,857.00
 UNIVERSITY OF NEW        and Targeted
 JERSEY                   Therapy: The
                          Evolving State of
                          Systemic Lupus
                          Erythematosus
                          Patient Care
------------------------------------------------------------------------
AMERICAN DIABETES        Diabetes is          03/01/2018     $300,000.00
 ASSOCIATION              Primary Core
                          Programs
------------------------------------------------------------------------
AMERICAN ASSOCIATION     AACR Annual          03/01/2018     $225,000.00
 FOR CANCER RESEARCH      Meeting--2018
------------------------------------------------------------------------
NATIONAL JEWISH HEALTH   A Severe Asthma      03/01/2018     $322,170.00
                          Roadmap for
                          Improved
                          Diagnosis and
                          Personalized
                          Treatment--A
                          Guided Workflow
------------------------------------------------------------------------
AMERICAN ASSOCIATION OF  California Chapter   03/01/2018      $10,000.00
 CLINICAL                 of the American
 ENDOCRINOLOGITS          Association of
                          Clinical
                          Endocrinologists
                          Presents Hot
                          Topics in
                          Diabetes and
                          Endocrinology for
                          Primary Care 2018
                          Series
------------------------------------------------------------------------
NATIONAL COMPREHENSIVE   NCCN 23rd Annual     03/02/2018     $100,000.00
 CANCER NETWORK, INC.     Conference:
                          Improving the
                          Quality,
                          Effectiveness,
                          and Efficiency of
                          Cancer CareTM
------------------------------------------------------------------------
EASTERN VIRGINIA         Turning the Tide     03/04/2018       $5,000.00
 MEDICAL SCHOOL           on Diabetes 2018
------------------------------------------------------------------------
THE UNIVERSITY OF        15th International   03/05/2018      $25,000.00
 CHICAGO                  Ultmann Chicago
                          Lymphoma
                          Symposium
------------------------------------------------------------------------
AMERICAN ASSOCIATION OF  Innovating           03/05/2018     $300,000.00
 CLINICAL                 Diabetes Care-Use
 ENDOCRINOLOGISTS         of Real-Time Data
                          to Transform
                          Clinical Practice
                          and Optimize
                          Patient Glucose
                          Management
------------------------------------------------------------------------
CARDIOVASCULAR RESEARCH  24th Annual          03/05/2018      $10,000.00
 FOUNDATION               Interventional
                          Cardiology
                          Fellows Course
------------------------------------------------------------------------
AMERICAN PHARMACISTS     APhA2018 Your        03/05/2018       $5,000.00
 ASSOC                    Annual Diabetes
                          Update
------------------------------------------------------------------------
CARDIOVASCULAR RESEARCH  DAPT Dilemmas: A     03/05/2018      $20,000.00
 FOUNDATION               Case-Based
                          Roundtable at
                          Fellows 2018
------------------------------------------------------------------------
AMERICAN UROLOGICAL      Japanese             03/05/2018      $40,000.00
 ASSOCIATION              Urological
                          Association (JUA)
                          Meeting
------------------------------------------------------------------------
NATIONAL COMPREHENSIVE   NCCN Foundation      03/06/2018     $171,801.00
 CANCER NETWORK, INC.     Young
                          Investigator
                          Awards
------------------------------------------------------------------------
PURDUE UNIVERSITY        Can You Do It        03/06/2018     $377,342.00
 OFFICE OF CONTINUING     Better?--A Unique
 PROFESSIONAL EDUCATION   Approach to
                          Enabling Improved
                          Asthma Management
------------------------------------------------------------------------
INTERNATIONAL            IASLC Workshop on    03/06/2018      $25,000.00
 ASSOCIATION FOR THE      Neopadjuvant
 STUDY OF LUNG CANCER     Therapy in Lung
                          Cancer
------------------------------------------------------------------------
UNT HEALTH SCIENCE       Filling the Gaps     03/07/2018       $4,750.00
 CENTER                   in Asthma Care--
                          Lessons Learned
                          from Asthma411
------------------------------------------------------------------------
ANNENBERG CENTER FOR     Updates in           03/07/2018     $155,000.00
 HEALTH SCIENCES AT       Precision
 EISENHOWER               Medicine
                          Elevating the
                          Treatment of
                          Severe,
                          Eosinophilic
                          Asthma
------------------------------------------------------------------------
AMERICAN ASSOCIATION OF  27th Annual          03/07/2018      $63,052.00
 CLINICAL                 Scientific and
 ENDOCRINOLOGITS          Clinical
                          Congress--Diabete
                          s Sessions
------------------------------------------------------------------------
NATIONAL COMPREHENSIVE   Support for NCCN     03/08/2018      $60,000.00
 CANCER NETWORK           Distribution of
                          the NCCN Clinical
                          Practice
                          Guidelines in
                          Oncology (NCCN
                          Guidelinesr) for
                          Management of
                          Immunotherapy-
                          Related
                          Toxicities Pocket
                          Guides
------------------------------------------------------------------------
BOARD OF REGENTS OF THE  2018 Pan Pacific     03/11/2018     $125,000.00
 UNIVERSITY OF NEBRASKA   Lymphoma
                          Conference
------------------------------------------------------------------------
SCRIPPS HEALTH           Fifth Annual         03/11/2018       $5,000.00
                          Clinical Advances
                          in Heart Failure
                          and Arrhythmias
------------------------------------------------------------------------
NORTHEAST GEORGIA        10th Annual          03/12/2018       $2,500.00
 MEDICAL CENTER           Northeast Georgia
                          STEMI Summit
------------------------------------------------------------------------
HEMATOLOGY/ONCOLOGY      HOPA 14th Annual     03/12/2018      $30,000.00
 PHARMACY ASSOCIATION     Conference
------------------------------------------------------------------------
CONQUER CANCER           2018 ASCO Annual     03/12/2018      $20,000.00
 FOUNDATION OF THE        Meeting Breast
 AMERICAN SOCIETY OF      Cancer Track
 CLINICAL ONCOLOGY
------------------------------------------------------------------------
CONQUER CANCER           2018 ASCO Annual     03/12/2018      $30,000.00
 FOUNDATION OF THE        Meeting
 AMERICAN SOCIETY OF      Genitourinary
 CLINICAL ONCOLOGY        Cancer Tracks
                          Bundle: Prostate
                          and Nonprostate
------------------------------------------------------------------------
THE GUTHY JACKSON        The Guthy-Jackson    03/12/2018      $25,000.00
 CHARITABLE FOUNDATION    Industry Council
------------------------------------------------------------------------
REGENTS OF THE           Making the           03/13/2018     $200,000.00
 UNIVERSITY OF            Connection
 CALIFORNIA               Between Patients
                          and Providers: A
                          Comprehensive
                          Overview of the
                          Modern Treatment
                          Strategies For
                          People With Type
                          1 and Type 2
                          Diabetes
------------------------------------------------------------------------
NATIONAL KIDNEY          Cardiovascular       03/13/2018     $232,979.00
 FOUNDATION               Risk in Patients
                          with Chronic
                          Kidney Disease
                          (CKD): The Impact
                          of Anemia
------------------------------------------------------------------------
ACADEMY OF MANAGED CARE  The Immuno-          03/13/2018      $35,000.00
 PHARMACY                 Oncology Pipeline
                          and the Managed
                          Care
                          Considerations
------------------------------------------------------------------------
INTERNATIONAL            IASLC                03/13/2018      $25,000.00
 ASSOCIATION FOR THE      Immunotherapy
 STUDY OF LUNG CANCER     Meeting
------------------------------------------------------------------------
ACS DIVISION OF          255th ACS National   03/13/2018       $5,000.00
 BIOCHEMICAL TECHNOLOGY   Meeting and
                          Exposition (BIOT
                          Division)
------------------------------------------------------------------------
AMERICAN ASSOCIATION     12th Biennial        03/14/2018      $15,000.00
 FOR CANCER RESEARCH      Ovarian Cancer
                          Research
                          Symposium
------------------------------------------------------------------------
AMERICAN HEART           Arteriosclerosis,    03/18/2018       $2,000.00
 ASSOCIATION              Thrombosis and
                          Vascular Biology
                          | Peripheral
                          Vascular Disease
                          2018Scientific
                          Sessions,
                          Vascular
                          Discovery: From
                          Genes to Medicine
------------------------------------------------------------------------
RILITE FOUNDATION        Lupus 21st Century   03/18/2018      $25,000.00
                          2018 Conference
------------------------------------------------------------------------
RHEUMATOLOGIC            4th International    03/19/2018      $10,000.00
 DERMATOLOGY SOCIETY      Conference on
 INC.                     Cutaneous Lupus
                          Erythematosus
------------------------------------------------------------------------
HOWARD UNIVERSITY        13th Annual          03/19/2018       $2,500.00
                          Kenneth Austin
                          Rheumatology
                          Symposium
------------------------------------------------------------------------
SOCIETY OF GYNECOLOGIC   SGO Lunch and        03/20/2018     $125,000.00
 ONCOLOGY                 Learn
                          Contemporary
                          Ovarian Cancer:
                          Keys to Therapies
                          and Integrated
                          Learning
------------------------------------------------------------------------
LYMPHOMA RESEARCH        Mantle Cell          03/20/2018      $20,000.00
 FOUNDATION               Lymphoma
                          Scientific
                          Workshop
------------------------------------------------------------------------
CANCER MOLECULAR         Molecular            03/21/2018       $5,000.00
 THERAPEUTICS RESEARCH    Therapeutics of
 ASSOCIATION              Cancer Research
                          Conference 2018
------------------------------------------------------------------------
PREVENTIVE               PCNA's 24th Annual   03/22/2018      $10,000.00
 CARDIOVASCULAR NURSES    Symposium
 ASSOCIATION
------------------------------------------------------------------------
ASPEN LUNG CONFERENCE    Thomas Petty Aspen   03/22/2018      $25,000.00
                          Lung Conference/
                          Translating
                          Resilience and
                          Pathogenesis to
                          Personalized
                          Therapy for COPD
------------------------------------------------------------------------
ANNENBERG CENTER FOR     Master Class for     03/22/2018      $24,246.27
 HEALTH SCIENCES          Oncologists--Hema
                          tology Track
------------------------------------------------------------------------
NATIONAL ASSOCIATION OF  Clinical Advances    03/25/2018      $15,000.00
 MANAGED CARE             in the Diagnosis,
 PHYSICIANS, INC.         Treatment and
                          Management of
                          COPD
------------------------------------------------------------------------
FOUNDATION FOR SURGICAL  American Head and    03/25/2018      $15,000.00
 FELLOWSHIPS              Neck Society
                          Annual Meeting--
                          Evaluating Head
                          and Neck Cancer
                          Care Through
                          Evidence Based
                          Medicine
------------------------------------------------------------------------
DUKE UNIVERSITY          Duke Debates:        03/25/2018      $15,000.00
                          Controversies in
                          the Management of
                          Patients with
                          Hematologic
                          Malignancies
------------------------------------------------------------------------
ICAHN SCHOOL OF          Mount Sinai          03/29/2018       $7,500.00
 MEDICINE AT MOUNT        Division of
 SINAI                    Occupational
                          Medicine Seminar
                          Series
------------------------------------------------------------------------
GORDON RESEARCH          Gordon Research      04/01/2018       $2,500.00
 CONFERENCE               Conference:
                          Mutagenesis--Mech
                          anisms of
                          Intrinsic and
                          Induced Genome
                          Instability
------------------------------------------------------------------------
THE UNIVERSITY OF        Frontiers in         04/02/2018      $25,000.00
 CHICAGO                  Precision
                          Medicine for
                          Inherited
                          Cancers: From
                          Risk Assessment
                          to Targeted
                          Therapies
------------------------------------------------------------------------
THE PENNSYLVANIA STATE   PeerView Live:       04/02/2018      $73,575.00
 UNIVERSITY               ``Unraveling the
                          Complex Treatment
                          Landscape for
                          Prostate Cancer:
                          Guidance for
                          Delivering
                          Evidence-Based,
                          Patient-Centered
                          Care''
                          (150204517)
------------------------------------------------------------------------
GORDON RESEARCH          2018 Gordon          04/03/2018       $2,500.00
 CONFERENCES              Research
                          Conference on
                          Medicinal
                          Chemistry
------------------------------------------------------------------------
CLEVELAND CLINIC         2018 Cleveland       04/03/2018       $5,000.00
 EDUCATION FOUNDATION     Breast Cancer
                          Summit:
                          Collaborating for
                          a Cure
------------------------------------------------------------------------
THE PENNSYLVANIA STATE   New Directions in    04/04/2018     $124,611.00
 UNIVERSITY               the Management of
                          Recurrent Ovarian
                          Cancer: Focus on
                          PARP Inhibitors
------------------------------------------------------------------------
ASSOCIATION FOR          Advancing Patient    04/04/2018     $416,900.00
 MOLECULAR PATHOLOGY      Care in NSCLC:
                          Breaking Down
                          Barriers
------------------------------------------------------------------------
CLEVELAND CLINIC         2018 Diabetes Day    04/04/2018       $5,000.00
 EDUCATIONAL FOUNDATION   23rd Annual
                          Symposium New
                          Frontiers in
                          Diabetes
------------------------------------------------------------------------
MEDICAL LEARNING         PeerView Master      04/04/2018     $370,100.00
 INSTITUTE, INC.          Class and
                          Practicum Live at
                          ASH 2018:
                          ``Exploring the
                          Present and
                          Future of BTK
                          Inhibition in B-
                          cell
                          malignancies:
                          Expert Insights
                          on Practical
                          Implications for
                          Patient
                          Management''
                          (150205092)
------------------------------------------------------------------------
AMERICAN UROLOGICAL      AUA2018              04/04/2018     $150,000.00
 ASSOCIATION              Highlights:
                          Immunotherapy in
                          GU Cancer
------------------------------------------------------------------------
ANNENBERG CENTER FOR     Master Class for     04/05/2018      $19,391.02
 HEALTH SCIENCES          Oncologists--Wome
                          n's Cancer Track
------------------------------------------------------------------------
FRIENDS OF CANCER        Friends of Cancer    04/08/2018     $100,000.00
 RESEARCH 2018            Research Programs
------------------------------------------------------------------------
THE HOPE FOUNDATION      2018 SWOG Group      04/08/2018      $10,000.00
                          Meetings
------------------------------------------------------------------------
CONQUER CANCER           2018 ASCO Annual     04/09/2018      $45,000.00
 FOUNDATION OF THE        Meeting
 AMERICAN SOCIETY OF      Gynecologic
 CLINICAL ONCOLOGY        Cancer Track
------------------------------------------------------------------------
LAHEY CLINIC HOSPITAL,   Cardiovascular       04/09/2018       $5,000.00
 INC.                     Disease State of
                          the Art 2018
------------------------------------------------------------------------
BOARD OF REGENTS FOR     Dissecting the       04/11/2018      $75,000.00
 UNIVERSITY OF NEBRASKA   Decision:
                          Documenting and
                          Discussing the
                          Clinical Practice
                          Patterns of
                          Hematologic
                          Oncology
                          Investigators in
                          the Management of
                          Chronic
                          Lymphocytic
                          Leukemia--An ISS
                          Held in
                          Conjunction with
                          the 2018 Pan
                          Pacific Lymphoma
                          Conference
------------------------------------------------------------------------
TRUSTEES OF BOSTON       CVD AND RENAL        04/11/2018     $109,420.00
 UNIVERSITY               DISEASE IN T2DM:
                          Pivotal Role of
                          Physician
                          Assistants in
                          Patient
                          Management
------------------------------------------------------------------------
CONQUER CANCER           2018 Conquer         04/12/2018     $253,000.00
 FOUNDATION OF THE        Cancer Foundation
 AMERICAN SOCIETY OF      of ASCO Career
 CLINICAL ONCOLOGY        Development Award
                          (CDA)
------------------------------------------------------------------------
AMERICAN COLLEGE OF      CHEST 2018 Post      04/12/2018      $25,000.00
 CHEST PHYSICIANS         Graduate Program
                          on Difficult to
                          Treat Asthma
------------------------------------------------------------------------
ECOG RESEARCH AND        ECOG-ACRIN 2018      04/12/2018       $5,000.00
 EDUCATION FOUNDATION,    Spring Group
 INC.                     Meeting
------------------------------------------------------------------------
LUPUS FOUNDATION OF NEW  Lupus Medical and    04/15/2018       $5,000.00
 ENGLAND                  Educational
                          Symposim
------------------------------------------------------------------------
HEART FAILURE SOCIETY    Future Leaders in    04/16/2018      $10,000.00
 OF AMERICA INC.          Heart Failure
                          Symposium
------------------------------------------------------------------------
AMERICAN ACADEMY OF CME  Applying the         04/17/2018     $313,595.00
 INC.                     Latest Evidence
                          to Improve Care
                          for Patients with
                          HR+/HER2-
                          Metastatic Breast
                          Cancer
------------------------------------------------------------------------
PRESIDENT AND FELLOWS    Practical            04/17/2018       $5,000.00
 OF HARVARD COLLEGE       Considerations
 ACTING THROUGH THE       and Rationale for
 DEPARTMENT OF GCE        Immunotherapy
                          2018
------------------------------------------------------------------------
AMERICAN ASSOCIATION OF  AACE 27th Annual     04/17/2018      $30,000.00
 CLINICAL                 Scientific &
 ENDOCRINOLOGITS          Clinical
                          Congress--Cardiov
                          ascular Track
------------------------------------------------------------------------
METABOLIC ENDOCRINE      2nd Annual Heart     04/18/2018      $50,000.00
 EDUCATION FOUNDATION     in Diabetes
------------------------------------------------------------------------
SOCIETY FOR              SCAI 2018            04/18/2018      $40,000.00
 CARDIOVASCULAR           Scientific
 ANGIOGRAPHY AND          Sessions
 INTERVENTIONS            featuring
 FOUNDATION               Controversies in
                          Interventional
                          Pharmacology
------------------------------------------------------------------------
AMERICAN HEART           STEMI Protocol       04/18/2018       $3,730.00
 ASSOCIATION              Stakeholder
                          Education
------------------------------------------------------------------------
ALZHEIMER'S ASSOCIATION  2018 Research        04/19/2018      $50,000.00
                          Roundtable
------------------------------------------------------------------------
PURDUE UNIVERSITY        Critical             04/23/2018     $575,210.00
                          Conversations on
                          Bruton's Tyrosine
                          Kinase Inhibitor
                          Development and
                          Use in B-Cell
                          Malignancies (CCO
                          GR Pgm)
------------------------------------------------------------------------
AMERICAN COLLEGE OF      Severe Asthma        04/23/2018      $60,000.00
 ALLERGY, ASTHMA AND      Shared Decision
 IMMUNOLOGY               Making Tool
                          Instructional
                          Video
------------------------------------------------------------------------
AMERICAN COLLEGE OF      Symposium--A         04/23/2018      $80,375.00
 ALLERGY, ASTHMA AND      Personalized
 IMMUNOLOGY               Approach to
                          Managing Patients
                          with Uncontrolled
                          Asthma / Shifting
                          Paradigms in
                          Management of
                          Severe Asthma:
                          Pathogenesis,
                          Phenotypes and
                          Personalized
                          Medicine
------------------------------------------------------------------------
MEDSTAR HEALTH, INC.     2018 MedStar         04/24/2018      $15,000.00
                          Health System
                          Prostate Cancer
                          Annual Meeting
------------------------------------------------------------------------
UT HEALTH SAN ANTONIO    3rd Annual Cardio    04/24/2018       $5,000.00
                          Renal Connections
------------------------------------------------------------------------
MEDSTAR HEALTH, INC.     Enhancing Health     04/24/2018      $10,000.00
                          System
                          Initiatives
                          Utilizing
                          Clinical Advances
                          to Optimize the
                          Diagnosis and
                          Treatment of
                          Prostate Cancer
------------------------------------------------------------------------
NATIONAL ASSOCIATION OF  Best Practices in    04/25/2018      $35,000.00
 MANAGED CARE             the Management of
 PHYSICIANS, INC.         Advanced Non-
                          Small Cell Lung
                          Cancer (NSCLC):
                          Individualizing
                          Therapy for
                          Optimized Patient
                          Outcomes
------------------------------------------------------------------------
TRUSTEES OF BOSTON       CVD AND RENAL        04/25/2018      $49,000.00
 UNIVERSITY               DISEASE IN T2DM:
                          Individualizing
                          Therapeutic
                          Options to Reduce
                          Comorbid Risk
------------------------------------------------------------------------
CONQUER CANCER           2018 Best of ASCO   04/25/2018     $120,000.00
 FOUNDATION OF THE        Meetings
 AMERICAN SOCIETY OF
 CLINICAL ONCOLOGY
------------------------------------------------------------------------
AMERICAN CHEMICAL        Recovery of          04/26/2018      $10,000.00
 SOCIETY, DIVISION OF     Biological
 BIOCHEMICAL              Products XVIII
 TECHNOLOGY, RECOVERY     Conference
 OF BIOLOGICAL PRODUCTS
------------------------------------------------------------------------
AMERICAN RADIUM SOCIETY  American Radium      04/26/2018      $10,000.00
                          Society 100th
                          Annual Meeting
------------------------------------------------------------------------
VANDERBILT UNIVERSITY    Midwest Islet Club   04/26/2018       $2,500.00
                          Meeting
------------------------------------------------------------------------
WEST PENN ALLEGHENY      2018                 04/29/2018       $5,000.00
 HEALTH SYSTEM, INC.      Cardiovascular
 DBA ALLEGHENY GENERAL    Medicine Update
 HOSPITAL                 Conference
------------------------------------------------------------------------
PRESIDENT AND FELLOWS    Diabetes Update      04/30/2018       $5,000.00
 OF HARVARD COLLEGE       2018
 ACTING THROUGH THE
 DEPARTMENT OF GCE
------------------------------------------------------------------------
ASPEN CANCER CONFERENCE  33rd Aspen Cancer    04/30/2018      $10,000.00
                          Conference
------------------------------------------------------------------------
TRUSTEES OF THE          6th Annual           04/30/2018      $20,000.00
 UNIVERSITY OF            Scientific
 PENNSYLVANIA/PERELMAN    Symposium: BRCA1,
 SCHOOL OF MEDICINE AT    BRCA2 and Beyond:
 THE UNIVERSITY OF PA     An Update on
                          Hereditary Cancer
------------------------------------------------------------------------
ASSOCIATION OF AMERICAN  2018 AACI/CCAF       05/01/2018      $15,000.00
 CANCER INSTITUTES        Annual Meeting
------------------------------------------------------------------------
ONCOLOGY NURSING         2018 ONS Annual      05/01/2018      $50,000.00
 SOCIETY                  Congress and two
                          Regional
                          Conferences
------------------------------------------------------------------------
TRUSTEES OF THE          2018 New Advances    05/03/2018      $10,000.00
 UNIVERSITY OF            in Lung Cancer:
 PENNSYLVANIA/PERELMAN    Stretching the
 SCHOOL OF MEDICINE AT    Envelope
 THE UNIVERSITY OF PA
------------------------------------------------------------------------
HEMATOLOGY ONCOLOGY      Immuno oncology      05/06/2018      $35,000.00
 PHARMACY ASSOCIATION     Educational
                          Modules for
                          Oncology
                          Pharmacists
------------------------------------------------------------------------
CANCER RESEARCH           2018                05/06/2018      $50,000.00
 INSTITUTE                International
                          Cancer
                          Immunotherapy
                          Conference
------------------------------------------------------------------------
AMERICAN ASSOCIATION     AACR Pancreatic      05/06/2018      $25,000.00
 FOR CANCER RESEARCH      Cancer: Advances
                          in Science and
                          Clinical Care
------------------------------------------------------------------------
ALLIANCE FOR CLINICAL    2018 Group           05/07/2018      $40,000.00
 TRIALS IN ONCOLOGY       Meetings
 FOUNDATION
------------------------------------------------------------------------
AMERICAN THORACIC        ATS 2018             05/07/2018      $40,000.00
 SOCIETY INC.             International
                          Conference--Selec
                          ted Sessions in
                          Lung Cancer
------------------------------------------------------------------------
AMERICAN SOCIETY OF      2018 ASH Meeting     05/08/2018      $50,000.00
 HEMATOLOGY               on Lymphoma
                          Biology
------------------------------------------------------------------------
LUNGEVITY FOUNDATION     LUNGevity            05/08/2018      $50,000.00
                          Foundation
                          Scientific and
                          Clinical
                          Roundtable--
                          Streamlining
                          Clinical Trials
                          2018
------------------------------------------------------------------------
HEMATOLOGY/ONCOLOGY      HOPA Early Career    05/08/2018      $60,000.00
 PHARMACY ASSOCIATION     Research Grant
------------------------------------------------------------------------
MEDICAL LEARNING         PeerView Live at     05/09/2018     $323,020.00
 INSTITUTE, INC.          ASTRO 2018--The
                          Era of
                          Immunotherapy in
                          Stage III NSCLC
                          (150205115)
------------------------------------------------------------------------
TRUSTEES OF THE          2018 Breast Cancer   05/09/2018       $5,000.00
 UNIVERSITY OF            Clinical Case
 PENNSYLVANIA/PERELMAN    Series: The Year
 SCHOOL OF MEDICINE AT    in Review
 THE UNIVERSITY OF PA
------------------------------------------------------------------------
HEART FAILURE SOCIETY    2018 HFSA Board      05/09/2018      $15,000.00
 OF AMERICA INC.          Certification
                          Review Course in
                          Advanced Heart
                          Failure and
                          Transplant
                          Cardiology
------------------------------------------------------------------------
SOCIETY FOR              Immuno-Oncology      05/10/2018      $25,000.00
 IMMUNOTHERAPY OF         Biomarkers State
 CANCER                   of the Art
------------------------------------------------------------------------
AMERICAN ACADEMY OF      AAPA 2018 Annual     05/10/2018      $10,000.00
 PHYSICIAN ASSISTANTS     Conference
------------------------------------------------------------------------
HDL WORKSHOP             HDL Workshop 2018    05/10/2018       $5,000.00
------------------------------------------------------------------------
LUPUS RESEARCH           Lupus Research       05/10/2018      $25,000.00
 ALLIANCE, INC.           Alliance 2018
                          Annual Scientific
                          Conference--Forum
                          for Discovery
------------------------------------------------------------------------
BOARD OF REGENTS FOR     Dissecting the       05/13/2018     $200,000.00
 UNIVERSITY OF NEBRASKA   Decision:
                          Documenting and
                          Discussing the
                          Clinical Practice
                          Patterns of
                          Hematologic
                          Oncology
------------------------------------------------------------------------
REGENTS OF THE           24th Annual San      05/13/2018      $10,000.00
 UNIVERSITY OF            Diego Heart
 CALIFORNIA               Failure Symposium
------------------------------------------------------------------------
CLEVELAND CLINIC         Intensive Review     05/15/2018      $10,000.00
 EDUCATIONAL FOUNDATION   of Cardiology
------------------------------------------------------------------------
GORDON RESEARCH          2018 Heterocyclic    05/15/2018       $2,000.00
 CONFERENCE               Gordon Research
                          Conference
------------------------------------------------------------------------
CARDIOVASCULAR RESEARCH  30th Annual          05/16/2018      $40,000.00
 FOUNDATION               Transcatheter
                          Cardiovascular
                          Therapeutics
------------------------------------------------------------------------
AMERICAN ACADEMY OF      2018 Family          05/16/2018      $19,000.00
 FAMILY PHYSICIANS        Medicine
                          Experience
                          Interactive
                          Lecture titled
                          Acute Coronary
                          Syndrome
------------------------------------------------------------------------
HUNTSVILLE HOSPITAL      RSS Breast Cancer    05/16/2018       $2,000.00
 FOUNDATION               Conference
------------------------------------------------------------------------
SOCIETY OF               2018 WCIO            05/20/2018      $15,000.00
 INTERVENTIONAL
 ONCOLOGY (SIO)
------------------------------------------------------------------------
UNIVERSITY OF            University of        05/20/2018      $24,300.00
 WASHINGTON SCHOOL OF     Washington Topics
 MEDICINE                 in Allergy and
                          Immunology
                          Teaching Series
------------------------------------------------------------------------
THE GOG FOUNDATION       10th Semi Annual     05/21/2018      $20,000.00
                          Meeting of NRG
                          Oncology
                          (formerly NCI
                          cooperatives
                          groups, GOG,
                          NSABP, RTOG)
------------------------------------------------------------------------
NORTHWESTERN UNIVERSITY  20th Annual Lynn     05/21/2018      $15,000.00
                          Sage Breast
                          Cancer Symposium
------------------------------------------------------------------------
AMERICAN ASSOCIATION     Molecular Biology    05/22/2018      $15,000.00
 FOR CANCER RESEARCH      in Clinical
                          Oncology Workshop
------------------------------------------------------------------------
UNIVERSITY OF COLORADO   Precision Medicine   05/23/2018      $20,000.00
                          in Autoimmunity
------------------------------------------------------------------------
MEDICAL LEARNING         PeerView Live at     05/23/2018     $313,240.00
 INSTITUTE, INC.          CAP18: Molecular
                          Testing for EGFR
                          Mutations in the
                          Context of a
                          Changing
                          Treatment
                          Landscape,
                          Evolving Testing
                          Options, and New
                          Guidelines
                          (150205165)
------------------------------------------------------------------------
THE UNIVERSITY OF TEXAS  2018 Lung Cancer     05/23/2018      $15,000.00
 SOUTHWESTERN MEDICAL     SPORE Workshop
 CENTER
------------------------------------------------------------------------
AMERICAN COLLEGE OF      ACEP18, ACEP         05/23/2018      $20,000.00
 EMERGENCY PHYSICIANS     National
                          Scientific
                          Assembly--Cardiov
                          ascular Track
------------------------------------------------------------------------
HOSPITAL QUALITY         Advances in the      05/23/2018     $222,127.50
 FOUNDATION, LLC          Management of
                          Acute and Chronic
                          Hyperkalemia: An
                          Update for
                          Emergency
                          Medicine,
                          Hospitalists and
                          Healthcare
                          Providers (MD, PA
                          and CRNP)
------------------------------------------------------------------------
GORDON RESEARCH          2018 Cardiac         05/23/2018       $5,000.00
 CONFERENCE               Regulatory
                          Mechanisms Gordon
                          Research
                          Conference
------------------------------------------------------------------------
CONQUER CANCER           2018 ASCO Annual     05/24/2018      $30,000.00
 FOUNDATION OF THE        Meeting Head and
 AMERICAN SOCIETY OF      Neck Cancer Track
 CLINICAL ONCOLOGY
------------------------------------------------------------------------
CONQUER CANCER           2018 ASCO Pre-       05/24/2018      $10,000.00
 FOUNDATION OF THE        Annual Meeting
 AMERICAN SOCIETY OF      Seminar: New
 CLINICAL ONCOLOGY        Drugs in Oncology
------------------------------------------------------------------------
FEDERATION OF CLINICAL   18th Annual          05/24/2018      $10,000.00
 IMMUNOLOGY SOCIETIES     Meeting of the
                          Federation of
                          Clinical
                          Immunology
                          Societies
------------------------------------------------------------------------
NATIONAL COMPREHENSIVE   2018-2019 Monthly    05/24/2018      $75,000.00
 CANCER NETWORK           Oncology Tumor
                          Boards: A
                          Multidisciplinary
                          Approach to
                          Individualized
                          Patient Care
------------------------------------------------------------------------
WINTHROP UNIVERSITY      3rd Annual NYU       05/24/2018       $3,000.00
 HOSPITAL                 Winthrop Breast
                          Health Symposium
------------------------------------------------------------------------
CONQUER CANCER           2018 ASCO Annual     05/27/2018      $25,000.00
 FOUNDATION OF THE        Meeting Lung
 AMERICAN SOCIETY OF      Cancer Track
 CLINICAL ONCOLOGY
------------------------------------------------------------------------
MISSOURI ACADEMY OF      Updates in           05/30/2018       $3,000.00
 PHYSICIANS ASSISTANTS    Treating Chronic
                          Obstructive
                          Pulmonary
                          Disorder
------------------------------------------------------------------------
MEDICAL LEARNING         Emergency Medicine   06/03/2018     $568,470.00
 INSTITUTE, INC.          and Immuno-
                          Oncology
                          Intersect:
                          Recognizing and
                          Managing Immune-
                          Related Adverse
                          Effects in the
                          Emergency
                          Department
                          (150205075)
------------------------------------------------------------------------
NATIONAL COMPREHENSIVE   NCCN 2018 Oncology   06/03/2018      $40,000.00
 CANCER NETWORK, INC.     Case Manager and
                          Medical Director
                          Program
------------------------------------------------------------------------
AMERICAN SOCIETY FOR     ASTRO 2018 60th      06/03/2018      $50,000.00
 RADIATION ONCOLOGY       Annual Meeting
------------------------------------------------------------------------
UNIVERSITY OF            2018 Pittsburgh      06/04/2018      $10,000.00
 PITTSBURGH               International
                          Lung Conference--
                          Pulmonary
                          Medicine: Basic
                          Biology and Novel
                          Therapies
------------------------------------------------------------------------
AEGEAN CONFERENCES,      2nd International    06/05/2018       $5,000.00
 INC.                     Conference on
                          Tissue Repair,
                          Regeneration, and
                          Fibrosis
------------------------------------------------------------------------
SYNAPTIV, INC.           Atlanta Lung         06/05/2018      $20,000.00
                          Cancer Symposium
                          2018
------------------------------------------------------------------------
SOCIETY FOR              NSCLC Treatment in   06/05/2018      $38,885.00
 TRANSLATIONAL ONCOLOGY   the Era of
                          Precision
                          Medicine: Case-
                          Based Insights
                          from ASCO 2018
------------------------------------------------------------------------
MEDICAL LEARNING         Traveling Master     06/06/2018     $390,030.00
 INSTITUTE, INC.          Class for
                          Emergency
                          Medicine
                          Specialists:
                          Urgent Care of
                          Patients
                          Receiving Cancer
                          Immunotherapy:
                          Recognition and
                          Management of
                          Immune-Mediated
                          Adverse Reactions
                          in the ED
------------------------------------------------------------------------
PRESIDENT AND FELLOWS    33rd Annual          06/06/2018      $15,000.00
 OF HARVARD COLLEGE       Critical Issues
                          In Tumor
                          Microenvironment:
                          Angiogenesis,
                          Metastasis and
                          Immunology
------------------------------------------------------------------------
KERN ASPEN LIPID         Metabolic            06/06/2018      $10,000.00
 CONFERENCE               Regulation of
                          Immunity,
                          Cardiometabolic
                          Diseases and
                          Cancer: New
                          Theraepeutic
                          Approaches
------------------------------------------------------------------------
SOCIETY OF TOXICOLOGIC   STP 37th Annual      06/06/2018       $3,000.00
 PATHOLOGY                Symposium:
                          KEEPING IT RENAL
------------------------------------------------------------------------
WEILL CORNELL MEDICAL    2nd Annual           06/10/2018      $15,000.00
 COLLEGE                  International
                          Conference
                          Immunotherapy
                          Radiotherapy
                          Combinations
------------------------------------------------------------------------
AMERICAN COLLEGE OF      2018 COPD Learning   06/10/2018       $5,000.00
 CHEST PHYSICIANS         Track
------------------------------------------------------------------------
AMERICAN COLLEGE OF      2018                 06/10/2018      $27,000.00
 CHEST PHYSICIANS         Interdisciplinary
                          Program--Lung
                          Cancer: 2018
                          Update in Staging
                          and Management
------------------------------------------------------------------------
AMERICAN COLLEGE OF      Breathing New Air    06/10/2018      $20,400.00
 OSTEOPATHIC INTERNISTS   into the
                          Treatment of COPD
                          and Asthma
------------------------------------------------------------------------
THE RECTOR AND VISITORS  PREP2018 Symposium   06/10/2018       $5,000.00
 OF THE UNIVERSITY OF
 VIRGINIA
------------------------------------------------------------------------
SOCIETY FOR NEURO-       3rd CNS Anticancer   06/11/2018      $15,000.00
 ONCOLOGY                 Drug Discovery
                          and Development
                          Conference
------------------------------------------------------------------------
ANNENBERG CENTER FOR     2018 JADPRO Live:    06/12/2018      $50,000.00
 HEALTH SCIENCES AT       The Annual APSHO
 EISENHOWER               Meeting--Sequenci
                          ng Therapies in
                          Indolent
                          Lymphomas
------------------------------------------------------------------------
AMERICAN COLLEGE OF      ACOI 2018 Annual     06/12/2018      $33,782.00
 OSTEOPATHIC INTERNISTS   Convention and
                          Scientific
                          Sessions:
                          Addressing Unmet
                          Needs in Type 2
------------------------------------------------------------------------
UNIVERSITY OF            Moving Toward A      06/13/2018      $59,912.00
 CINCINNATI               New Standard of
                          Care: Checkpoint
                          Inhibitors in
                          Advanced
                          Urothelial Cancer
------------------------------------------------------------------------
AMERICAN ASSOCIATION OF  Reducing             06/13/2018     $178,188.13
 DIABETES EDUCATORS       Cardiovascular
                          Risk in T2DM with
                          SGLT2 Inhibitors
                          and GLP1-Receptor
                          Antagonists:
                          Translating
                          Evidence into
                          Patient Outcomes
------------------------------------------------------------------------
SOCIETY FOR NEURO-       23rd Annual          06/13/2018      $75,000.00
 ONCOLOGY                 Scientific
                          Meeting of the
                          Society for Neuro-
                          Oncology
------------------------------------------------------------------------
AMERICAN COLLEGE OF      2018 Lung Cancer     06/13/2018      $70,000.00
 CHEST PHYSICIANS         Learning Track
------------------------------------------------------------------------
UNIVERSITY OF            Request for 2018     06/14/2018       $5,000.00
 CALIFORNIA BERKELEY      Funding for the
 FOUNDATION               Forum for
                          Collaborative
                          Research's
                          Program on HBV
------------------------------------------------------------------------
JOHNS HOPKINS            OncologyConsults.c   06/15/2018      $89,885.00
 UNIVERSITY SCHOOL OF     om Improving
 MEDICINE                 Outcomes in Stage
                          III NSCLC The
                          Emerging Role of
                          Immunotherapy in
                          Curbing Disease
                          Progression
------------------------------------------------------------------------
SOCIETY FOR              Advances in Cancer   06/17/2018     $500,000.00
 IMMUNOTHERAPY OF         ImmunotherapyT
 CANCER                   2018-19
                          Educational
                          Program Series
------------------------------------------------------------------------
METABOLIC ENDOCRINE      Medications' Class   06/19/2018     $100,000.00
 EDUCATION FOUNDATION     Effects in DM and
                          CVD--All you need
                          to know- and
                          never asked.
------------------------------------------------------------------------
MEDICAL LEARNING         PeerView Live at     06/21/2018     $262,040.00
 INSTITUTE, INC.          ASCP 2018:
                          Navigating the
                          Complexities of
                          Molecular Testing
                          for EGFR
                          Mutations to
                          Guide Selection
                          of EGFR-Targeted
                          Therapy for
                          Patients With
                          Lung Cancer
                          (150205135)
------------------------------------------------------------------------
NORTHWESTERN UNIVERSITY  Lurie Cancer         06/21/2018      $10,000.00
                          Center
                          Multidisciplinary
                          Head and Neck
                          Symposium
------------------------------------------------------------------------
CHARLOTTE AHEC           30th Annual Fall     06/25/2018       $5,000.00
                          Foliage Cancer
                          Conference
------------------------------------------------------------------------
KEYSTONE SYMPOSIA ON     Integrated           06/25/2018       $6,000.00
 MOLECULAR AND CELLULAR   Pathways of
 BIOLOGY                  Disease in NASH
                          and NAFLD
------------------------------------------------------------------------
AMERICAN SOCIETY OF      ASN Kidney Week      06/25/2018      $20,000.00
 NEPHROLOGY               Educational
                          Session Support
------------------------------------------------------------------------
GORDON RESEARCH          DNA Topoisomerases   06/25/2018      $10,000.00
 CONFERENCE               in Biology and
                          Medicine
------------------------------------------------------------------------
INDUSTRY NETWORKING      BioHealth Capital    06/25/2018      $10,000.00
 GROUP                    Region Workforce
                          Community
                          Engagement
------------------------------------------------------------------------
AMERICAN COLLEGE OF      Unraveling the       07/01/2018      $33,782.00
 OSTEOPATHIC INTERNISTS   Effects of
                          Antihyperglycemic
                          Agents on
                          Cardiovascular
                          Risk
------------------------------------------------------------------------
MEDICAL LEARNING         PeerView Live at     07/02/2018     $262,040.00
 INSTITUTE, INC.          ASCP 2018:
                          Advances and
                          Challenges in
                          Refining the Use
                          of Cancer
                          Immunotherapies
                          Through Biomarker
                          Testing
                          (150205136)
------------------------------------------------------------------------
ENDOCRINE FELLOWS        Fifth Annual         07/02/2018     $250,000.00
 FOUNDATION               Research Forum
------------------------------------------------------------------------
SOCIETY FOR              SITC 2018 Workshop   07/02/2018     $100,000.00
 IMMUNOTHERAPY OF         on Nutrition,
 CANCER                   Metabolism and
                          the Microbiome in
                          Cancer Therapy
------------------------------------------------------------------------
AMERICAN SOCIETY OF      The Role of          07/02/2018     $167,500.00
 NEPHROLOGY               Hypoxia-Inducible
                          Factors and
                          Inflammation in
                          the Anemia of
                          Kidney Disease
------------------------------------------------------------------------
AMERICAN ACADEMY OF      Managing             07/04/2018     $160,000.00
 PHYSICIAN ASSISTANTS     Cardiovascular
                          Risk Factors in
                          Patients with
                          Type 2 Diabetes:
                          Emerging Concepts
------------------------------------------------------------------------
AMERICAN SOCIETY OF      ASH Meeting on       07/04/2018      $60,000.00
 HEMATOLOGY               Hematologic
                          Malignancies
------------------------------------------------------------------------
AMERICAN HEART           Scientific           07/05/2018      $20,000.00
 ASSOCIATION              Sessions 2018
                          Dedicated
                          Programming on
                          Acute Coronary
                          Syndrome
------------------------------------------------------------------------
BREATHE CALIFORNIA OF    2018 BREATHE         07/08/2018       $3,000.00
 LOS ANGELES COUNTY       California of Los
                          Angeles County
                          10th Annual COPD
                          Conference
------------------------------------------------------------------------
SOCIETY FOR INDUSTRIAL   SIMB Annual          07/08/2018       $3,000.00
 MICROBIOLOGY AND         Meeting
 BIOTECHNOLOGY
------------------------------------------------------------------------
JOSLIN DIABETES CENTER,  2018 AANHPI          07/08/2018       $5,000.00
 INC.                     Diabetes
                          Coalition
                          Conference The
                          Future of
                          Population
                          Diabetes Research
                          and Advocacy:
                          Asian American
                          Native Hawaiian
                          Pacific Islanders
------------------------------------------------------------------------
ACS DIVISION OF          Division of          07/09/2018       $2,500.00
 MEDICINAL CHEMISTRY      Medicinal
                          Chemistry Program
                          256th ACS
                          national meeting
------------------------------------------------------------------------
GORDON RESEARCH          Gordon Research      07/10/2018      $10,000.00
 CONFERENCES, INC.        Conference Tissue
                          Niches and
                          Resident Stem
                          Cells in Adult
                          Epithelia
------------------------------------------------------------------------
NORTH AMERICAN           Reducing             07/11/2018      $60,000.00
 THROMBOSIS FORUM         Cardiovascular
                          Risk in Patients
                          with Diabetes: A
                          Comprehensive Yet
                          Concise Patient
                          Focused Action
                          Plan
------------------------------------------------------------------------
AMERICAN ACADEMY OF      36th Annual Aspen    07/11/2018       $3,000.00
 ALLERGY ASTHMA AND       Allergy
 IMMUNOLOGY               Conference
------------------------------------------------------------------------
SOCIETY FOR              SITC 33rd Annual     07/16/2018     $400,000.00
 IMMUNOTHERAPY OF         Meeting
 CANCER
------------------------------------------------------------------------
SOCIETY FOR              SITC Cancer          07/16/2018      $67,500.00
 IMMUNOTHERAPY OF         Immunotherapy
 CANCER                   Sparkathon 2018--
                          Emerging Leaders
                          Igniting
                          Innovation
------------------------------------------------------------------------
AMERICAN COLLEGE OF      Respiratory          07/16/2018      $35,000.00
 CHEST PHYSICIANS         Syncytial Virus
                          (RSV) Education
                          Program
------------------------------------------------------------------------
BINAYTARA FOUNDATION     6th International    07/16/2018       $5,000.00
                          Conference on
                          Advances in
                          Hematology and
                          Oncology
------------------------------------------------------------------------
SOCIETY FOR MUCOSAL      Mucosal Immunology   07/16/2018      $10,000.00
 IMMUNOLOGY               Course and
                          Symposium
------------------------------------------------------------------------
BAYLOR COLLEGE OF        Breast Cancer        07/17/2018       $3,000.00
 MEDICINE                 Research and
                          Education program
------------------------------------------------------------------------
AMERICAN ASSOCIATION     AACR Conference on   07/17/2018      $25,000.00
 FOR CANCER RESEARCH      The Science of
                          Cancer Health
                          Disparities
------------------------------------------------------------------------
MEDICAL LEARNING         PeerView Live at     07/18/2018     $164,230.00
 INSTITUTE, INC.          CAP18: The
                          Central Role of
                          Biomarker Testing
                          in Piecing
                          Together the
                          Immuno-Oncology
                          Puzzle in the Era
                          of Precision
                          Medicine
                          (150205123)
------------------------------------------------------------------------
PENNSYLVANIA STATE       PeerView inClinic,   07/18/2018      $32,330.00
 UNIVERSITY               Building
                          Innovative
                          Treatment Options
                          for Patients with
                          B-cell
                          Malignancies:
                          Practical
                          Insights on
                          Clinical Evidence
                          and Integration
                          Strategies
                          150205182
------------------------------------------------------------------------
ANNENBERG CENTER FOR     2018 JADPRO Live:    07/19/2018      $50,000.00
 HEALTH SCIENCES AT       The Annual APSHO
 EISENHOWER               Meeting--Sequenci
                          ng of Treatments
                          for Patients with
                          Ovarian Cancer
------------------------------------------------------------------------
AMERICAN SOCIETY OF      ASH Scholar Awards   07/20/2018     $100,000.00
 HEMATOLOGY
------------------------------------------------------------------------
AMERICAN SOCIETY OF      60th ASH Annual      07/20/2018     $150,000.00
 HEMATOLOGY               Meeting
------------------------------------------------------------------------
AMERICAN ASSOCIATION     AACR Cancer Health   07/22/2018      $25,000.00
 FOR CANCER RESEARCH      Disparities Think
                          Tank
------------------------------------------------------------------------
ASSOCIATION OF           Association of       07/23/2018      $10,000.00
 PHYSICIAN ASSISTANTS     Physician
 IN ONCOLOGY              Assistants in
                          Oncology 21st
                          Annual Conference
------------------------------------------------------------------------
ANNENBERG CENTER FOR     2018 JADPRO Live:    07/24/2018      $50,000.00
 HEALTH SCIENCES AT       The Annual APSHO
 EISENHOWER               Meeting--Manageme
                          nt of Side
                          Effects for
                          Patients with
                          Multi-Modality
                          Therapy in
                          Thoracic Oncology
------------------------------------------------------------------------
AMERICAN SOCIETY OF      Kidney Health        07/24/2018      $30,000.00
 NEPHROLOGY               Initiative
------------------------------------------------------------------------
GORDON RESEARCH          2018 Gordon          07/26/2018       $2,500.00
 CONFERENCES              Research
                          Conference and
                          Seminar on Cell
                          Death
------------------------------------------------------------------------
JOHNS HOPKINS            Fifth Annual         07/29/2018      $10,000.00
 UNIVERSITY SCHOOL OF     Metastatic Breast
 MEDICINE                 Cancer Conference
------------------------------------------------------------------------
AMERICAN ASSOCIATION     AACR Translational   07/31/2018      $25,000.00
 FOR CANCER RESEARCH      Cancer Research
                          for Basic
                          Scientists
                          Workshop
------------------------------------------------------------------------
BOARD OF REGENTS FOR     Virtual              08/01/2018      $75,000.00
 UNIVERSITY OF NEBRASKA   Challenging Case
                          Clinic: B-Cell
                          Lymphomas
------------------------------------------------------------------------
MASSACHUSETTS GENERAL    Gene Panel           08/01/2018     $100,000.00
 HOSPITAL                 Testing: Decision
                          Aid
------------------------------------------------------------------------
LUNG CANCER ALLIANCE     Florida and          08/01/2018     $199,200.00
                          Georgia Lung
                          Cancer Screening
                          Demonstration
                          Project
------------------------------------------------------------------------
YALE SCHOOL OF MEDICINE  Severe Asthma 2018   08/01/2018      $15,000.00
                          Advances in
                          Pathogenesis and
                          Treatment
------------------------------------------------------------------------
UTAH CHAPTER OF THE      Rockies Chapter      08/02/2018       $3,000.00
 AMERICAN COLLEGE OF      Meeting
 CARDIOLOGY
------------------------------------------------------------------------
SOCIETY FOR              Immune Escape:       08/02/2018      $25,000.00
 IMMUNOTHERAPY OF         Current
 CANCER                   Understanding of
                          Mechanisms and
                          Advances in
                          Therapeutics
                          Approaches
------------------------------------------------------------------------
LUNG CANCER ALLIANCE     Florida and          08/02/2018     $147,972.00
                          Georgia Lung
                          Cancer Screening
                          Demonstration
                          Project
------------------------------------------------------------------------
NATIONAL JEWISH HEALTH   23rd Annual          08/02/2018       $5,000.00
                          Regional Allied
                          Health
                          Conference:
                          Current
                          Perspectives in
                          Asthma, Allergy,
                          and Pulmonary
                          Practice
------------------------------------------------------------------------
AMERICAN ASSOCIATION     FDA-AACR Workshop    08/02/2018      $25,000.00
 FOR CANCER RESEARCH      on Non-clinical
                          Models for Safety
                          Assessment of
                          Immunooncology
                          Products
------------------------------------------------------------------------
NATIONAL ASSOCIATION OF  Novel Treatment      08/06/2018      $35,000.00
 MANAGED CARE             Advances and
 PHYSICIANS, INC.         Approaches in the
                          Management of
                          Advanced Breast
                          Cancer: Expert
                          Strategies for
                          Individualized
                          Treatment
------------------------------------------------------------------------
NATIONAL ASSOCIATION OF  New Frontiers in     08/06/2018      $45,000.00
 MANAGED CARE             the Management of
 PHYSICIANS, INC.         Ovarian Cancer:
                          Exploring the
                          Role of PARP
                          Inhibitors in the
                          Evolving
                          Treatment
                          Paradigm
------------------------------------------------------------------------
SOCIETY FOR              2018 SITC Primer     08/07/2018      $50,000.00
 IMMUNOTHERAPY OF         on Tumor
 CANCER                   Immunology and
                          Cancer
                          ImmunotherapyT
------------------------------------------------------------------------
SOCIETY FOR              SITC 2018 Grant      08/07/2018      $10,000.00
 IMMUNOTHERAPY OF         Writing Workshop:
 CANCER                   Grant Writing:
                          From Start to
                          Finish, and Then
                          Starting Again
------------------------------------------------------------------------
AMERICAS HEALTH          The Diagnosis and    08/07/2018      $85,240.00
 FOUNDATION               Treatment of
                          Hereditary Breast
                          and Ovarian
                          Cancer Syndrome
                          in Brazil
------------------------------------------------------------------------
ADMINISTRATORS OF THE    18th Annual SSCI     08/10/2018      $55,000.00
 TULANE EDUCATION FUND    Nephrology Young
                          Investigators
                          Forum
------------------------------------------------------------------------
NATIONAL KIDNEY          Joint Analyses of    08/10/2018     $105,895.00
 FOUNDATION               GFR slope and
                          Change in
                          Albuminuria by
                          AstraZeneca and
                          the CKDEPI
                          Collaboration
------------------------------------------------------------------------
ANNENBERG CENTER FOR     JADPRO Live 2018:    08/12/2018      $25,000.00
 HEALTH SCIENCES AT       New Drug Updates
 EISENHOWER
------------------------------------------------------------------------
UNIVERSITY OF FLORIDA    Vascular Biology     08/12/2018       $7,500.00
                          Working Group
                          Global Chapter
                          Meeting
------------------------------------------------------------------------
NATIONAL COMPREHENSIVE   Optimizing Small     08/12/2018      $50,000.00
 CANCER NETWORK, INC.     Molecule
                          Inhibitor Therapy
                          for Relapsed/
                          Refractory B-cell
                          Lymphomas
------------------------------------------------------------------------
NATIONAL ASSOCIATION OF  Improving Clinical   08/12/2018      $35,000.00
 MANAGED CARE             and Economic
 PHYSICIANS, INC.         Outcomes with
                          Emerging
                          Therapies in the
                          Management of
                          Chronic
                          Lymphocytic
                          Leukemia (CLL)
------------------------------------------------------------------------
NATIONAL ASSOCIATION OF  Optimizing           08/13/2018      $35,000.00
 MANAGED CARE             Treatment
 PHYSICIANS, INC.         Strategies in the
                          Management of
                          Advanced Non-
                          Small Cell Lung
                          Cancer (NSCLC):
                          Individualized
                          Therapy for
                          Improved Patient
                          Outcomes
------------------------------------------------------------------------
NATIONAL COMPREHENSIVE   NCCN 13th Annual     08/13/2018      $75,000.00
 CANCER NETWORK, INC.     Congress:
                          Hematologic
                          MalignanciesTM
------------------------------------------------------------------------
AMERICAN PANCREATIC      49th Annual          08/13/2018      $25,000.00
 ASSOCIATION, INC.        Meeting of the
                          American
                          Pancreatic
                          Association
------------------------------------------------------------------------
REGENTS OF THE           16th Annual          08/14/2018      $50,000.00
 UNIVERSITY OF            Nephrology Young
 CALIFORNIA               Investigators
                          Forum
------------------------------------------------------------------------
PENNSYLVANIA STATE       PeerView             08/15/2018     $115,000.00
 UNIVERSITY COLLEGE OF    MasterClass:
 MEDICINE                 Innovative
                          Therapy in B-Cell
                          Malignancies: An
                          Expert Tumor
                          Board on Novel
                          Agent Classes in
                          CLL, FL, and MCL
                          (150205208)
------------------------------------------------------------------------
ASSOCIATION OF           Series of AUTM       08/15/2018      $25,287.50
 UNIVERSITY TECHNOLOGY    2019 Annual
 MANAGERS INC.            Meetings
------------------------------------------------------------------------
TRANSLATIONAL RESEARCH   TRIO-US & UCLA       08/16/2018       $5,000.00
 IN ONCOLOGY-US, INC.     Annual Research
                          Conference
------------------------------------------------------------------------
DANA-FARBER CANCER       IWWM10--Internatio   08/17/2018     $100,000.00
 INSTITUTE                nal Workshop on
                          Waldenstroms
                          macroglobulinemia
------------------------------------------------------------------------
MEDICAL LEARNING         Integrating BTK      08/20/2018     $245,090.00
 INSTITUTE, INC.          Inhibitors into
                          the Management of
                          B cell
                          Malignancies: How
                          is Evidence
                          Driving Patient
                          Care
------------------------------------------------------------------------
MEDICAL LEARNING         CRI-AACR ISS--       08/20/2018     $324,460.00
 INSTITUTE, INC.          Improving Patient
                          Outcomes With
                          Cancer
                          Immunotherapies
                          and Combinations
                          Throughout the
                          Continuum of Lung
                          Cancer
                          (150205201)
------------------------------------------------------------------------
AMERICAN NEPHROLOGY      ANNA Fall Meeting    08/20/2018      $42,500.00
 NURSES ASSOCIATION       CE Symposium
 (ANNA)
------------------------------------------------------------------------
AMERICAN SOCIETY OF      Risk and Treatment   08/20/2018     $125,000.00
 NEPHROLOGY               of Hyperkalemia
------------------------------------------------------------------------
AMERICAN ASSOCIATION     AACR-AstraZeneca     08/20/2018     $276,000.00
 FOR CANCER RESEARCH      Lymphoma Research
                          Fellowships
------------------------------------------------------------------------
SOCIETY FOR              2019 SITC-           08/20/2018     $120,000.00
 IMMUNOTHERAPY OF         AstraZeneca
 CANCER                   Immunotherapy in
                          Lung Cancer
                          Clinical
                          Fellowship
------------------------------------------------------------------------
GBMC HEALTHCARE          Advances in          08/21/2018       $2,000.00
                          Treatment and
                          Management of
                          Ovarian Cancer
------------------------------------------------------------------------
NATIONAL COMPREHENSIVE   PARP Inhibitors in   08/21/2018     $240,000.00
 CANCER NETWORK           Breast Cancer:
                          Expert
                          Perspectives on
                          Clinical
                          Application and
                          Genetic Testing
------------------------------------------------------------------------
UT HEALTH SCIENCE        41st Annual San      08/21/2018      $75,000.00
 CENTER AT SAN ANTONIO    Antonio Breast
 SCHOOL OF MEDICINE       Cancer Symposium
 OFFICE OF CME
------------------------------------------------------------------------
MEDICAL LEARNING         PeerView Live--The   08/22/2018     $269,660.00
 INSTITUTE, INC.          Evolving Role of
                          Immunotherapy as
                          a Component of
                          Multi-Modal
                          Therapy in
                          Earlier Stages of
                          Lung Cancer:
                          Rationale,
                          Current Evidence,
                          Key Trials, and
                          Implications for
                          Multidisciplinary
                          Care (150205392)
------------------------------------------------------------------------
TEMPLE UNIVERSITY LUNG   Severe               08/26/2018      $65,000.00
 CENTER- OF THE           Uncontrolled
 COMMONWEALTH SYSTEM OF   Asthma:
 HIGHER EDUCATION         Definition,
                          Management, and
                          Advance Therapies
------------------------------------------------------------------------
OHIO CHAPTER OF THE      28th Annual          08/26/2018       $4,500.00
 AMERICAN COLLEGE OF      Meeting of the
 CARDIOLOGY               Ohio Chapter of
                          the American
                          College of
                          Cardiology
------------------------------------------------------------------------
PROSTATE CANCER          25th Annual          08/27/2018      $20,000.00
 FOUNDATION               Scientific
                          Retreat
------------------------------------------------------------------------
AMERICAN UROLOGICAL      Advancing the        08/27/2018      $25,000.00
 ASSOCIATION EDUCATION    Treatment of
 AND RESEARCH, INC.       Genitourinary
                          Cancer
------------------------------------------------------------------------
THE ICAHN SCHOOL OF      The Lancet Women     08/30/2018      $50,000.00
 MEDICINE AT MOUNT        and
 SINAI                    Cardiovascular
                          Disease
                          Commission
------------------------------------------------------------------------
NATIONAL COMPREHENSIVE   Behind the           08/30/2018      $25,000.00
 CANCER NETWORK           Guidelines:
                          Insights into the
                          Standard of Care
                          in Oncology 2019
------------------------------------------------------------------------
NATIONAL COMPREHENSIVE   Behind the           08/30/2018      $25,000.00
 CANCER NETWORK           Guidelines:
                          Insights into the
                          Standard of Care
                          in Oncology 2019
------------------------------------------------------------------------
THE BOARD OF TRUSTREES   Stanford Review of   09/05/2018       $5,000.00
 OF THE LELAND STANFORD   the 60th Annual
 JUNIOR UNIVERSITY ON     American Society
 BEHALF OF ITS SCHOOL     of Hematology
 OF MEDICINE              Meeting 2019
------------------------------------------------------------------------
INTERNATIONAL CYTOKINE   6th Annual Meeting   09/11/2018      $20,000.00
 AND INTERFERON SOCIETY   of the
 INC.                     International
                          Cytokine and
                          Interferon
                          Society
------------------------------------------------------------------------
CEDARS-SINAI             7th Annual New       09/11/2018      $10,000.00
                          Therapeutics in
                          Oncology: The
                          Road to
                          Personalized
                          Medicine
------------------------------------------------------------------------
MERCY HEALTH FOUNDATION  2019 Tri-State ASH   09/11/2018       $5,000.00
                          Update
------------------------------------------------------------------------
DUKE UNIVERSITY          Duke Stanford CEC    09/18/2018      $20,000.00
                          Summit:
                          Scientific,
                          Regulatory and
                          Operational Best
                          Practices
------------------------------------------------------------------------
KENTUCKY ACADEMY OF      Breast Cancer--      09/18/2018       $3,000.00
 PHYSICIAN ASSISTANTS     Diagnosis and
                          Patient Treatment
                          Options
------------------------------------------------------------------------
THE UNIVERSITY OF TEXAS  13th Update on the   09/20/2018       $5,000.00
 MD ANDERSON CANCER       Management of
 CENTER                   Genitourinary
                          Malignancies
------------------------------------------------------------------------
NATIONAL COMPREHENSIVE   NCCN 2019 Congress   09/20/2018      $50,000.00
 CANCER NETWORK, INC.     SeriesTM: Breast
                          Cancer with
                          Updates from the
                          2018 San Antonio
                          Breast Cancer
                          Symposium
------------------------------------------------------------------------
AMERICAN SOCIETY OF      Hematology 2018:     09/21/2018     $100,000.00
 HEMATOLOGY               the ASH Education
                          Program Book
------------------------------------------------------------------------
PENN STATE COLLEGE OF    Consensus or         09/23/2018      $75,000.00
 MEDICINE                 Controversy?
                          Clinical
                          Investigators
                          Provide
                          Perspectives on
                          the Current and
                          Future Management
                          of Patients with
                          Prostate Cancer--
                          An ISS Held as a
                          Premium Ancillary
                          Educational Event
                          During the 2019
                          Genitourinary
                          Cancers Symposium
------------------------------------------------------------------------
HARTFORD HOSPITAL        34th Annual          09/23/2018       $5,000.00
                          Cardiovascular
                          Symposium
                          presented by
                          Hartford
                          HealthCare
------------------------------------------------------------------------
JOHN HOPKINS UNIVERSITY  Novel Therapeutic    09/24/2018       $5,000.00
                          Approaches to
                          Allergic Diseases
------------------------------------------------------------------------
INTERNATIONAL SOCIETY    Advances in          09/24/2018       $2,500.00
 FOR MAGNETIC RESONANCE   Multiscale Cancer
 IN MEDICINE              Detection: From
                          Micro to Macro
------------------------------------------------------------------------
PARENTERAL DRUG          PDA Universe of      10/01/2018      $24,000.00
 ASSOCIATION (PDA)        Pre-filled
                          Syringes and
                          Injection Devices
------------------------------------------------------------------------
KEYSTONE SYMPOSIA ON     2019 Keystone        10/01/2018      $25,000.00
 MOLECULAR AND CELLULAR   Symposia
 BIOLOGY                  Directors' Fund
------------------------------------------------------------------------
MEMORIAL SLOAN           State-of-the-Art     10/01/2018       $5,000.00
 KETTERING CANCER         Gynecologic
 CENTER                   Surgery and
                          Ovarian Cancer
                          Management
                          Conference 2018
------------------------------------------------------------------------
UNIVERSITY OF TEXAS      Official Best of     10/02/2018      $60,000.00
 HEALTH SCIENCE CENTER    San Antonio
 AT SAN ANTONIO           Breast Cancer
                          Symposium
------------------------------------------------------------------------
AMERICAN ASSOCIATION     AACR-AstraZeneca     10/03/2018     $276,000.00
 FOR CANCER RESEARCH      Immuno-Oncology
                          Research
                          Fellowships
------------------------------------------------------------------------
MEDCHI, THE MARYLAND     OPTIMAL DURATION      10/8/2018     $387,213.13
 STATE MEDICAL SOCIETY    OF ANTIPLATELET
                          THERAPY AFTER
                          PCI: The Case for
                          Longerterm Dual
                          Antiplatelet
                          Therapy in
                          Patients with
                          History of MI
------------------------------------------------------------------------
AMERICAN COLLEGE OF      Symposium 4:         10/08/2018       $5,000.00
 TOXICOLOGY               Update on RNA
                          Therapies:
                          Challenges and
                          Opportunities,
                          American College
                          of Toxicology
                          39th Annual
                          Meeting
------------------------------------------------------------------------
PEPTIDE THERAPEUTICS     13th Annual          10/08/2018      $15,000.00
 FOUNDATION               Peptide
                          Therapeutics
                          Symposium
------------------------------------------------------------------------
UNIVERSITY OF NEBRASKA   7th International    10/09/2018       $5,000.00
 MEDICAL CENTER           Conference on
                          Gram-Positive
                          Pathogens
------------------------------------------------------------------------
JOHNS HOPKINS            2019 Atlanta         10/09/2018      $10,000.00
 UNIVERSITY SCHOOL OF     Breast Cancer
 MEDICINE OFFICE OF       Symposium
 CONTINUING MEDICAL
 EDUCATION
------------------------------------------------------------------------
LYMPHOMA RESEARCH        LRF Postdoctoral     10/10/2018     $105,000.00
 FOUNDATION               Fellowship
------------------------------------------------------------------------
THE GOG FOUNDATION INC.  11th Semi Annual     10/10/2018      $20,000.00
                          Meeting of NRG
                          Oncology
                          (formerly GOG,
                          NSABP, RTOG)
                          cooperative
                          groups
------------------------------------------------------------------------
THE UNIVERSITY OF        Chicago Lung         10/10/2018      $10,000.00
 CHICAGO                  Cancer Updates
                          2018
------------------------------------------------------------------------
AMERICAN ASSOCIATION OF  The Liver Meeting    10/11/2018      $15,000.00
 THE STUDY OF LIVER       2018 Park Benches
 DISEASES                 Support
------------------------------------------------------------------------
NATIONAL ANIMAL          The Continued        10/14/2018       $2,000.00
 INTEREST ALLIANCE        Importance of
                          Animal Research
------------------------------------------------------------------------
AMERICAN ASSOCIATION     AACR-AstraZeneca     10/17/2018     $276,000.00
 FOR CANCER RESEARCH      Lung Cancer
                          Research
                          Fellowships
                          (Driver
                          Mutations)
------------------------------------------------------------------------
THE COOPER HEALTH        Contemporary         10/22/2018       $2,500.00
 SYSTEM                   Practices in
                          Cardiology
------------------------------------------------------------------------
AMERICAN SOCIETY OF      2019 Highlights of   10/22/2018     $100,000.00
 HEMATOLOGY               ASH in North
                          America
------------------------------------------------------------------------
EMORY UNIVERSITY SCHOOL  3rd National         10/24/2018       $5,000.00
 OF MEDICINE              Congress on the
                          Prevention of
                          Diabetes and Its
                          Complications
------------------------------------------------------------------------
MEMORIAL SLOAN           2018 Annual Cancer   10/24/2018       $5,000.00
 KETTERING CANCER         Treatment-Related
 CENTER                   Adverse Events
                          Symposium
------------------------------------------------------------------------
ECOG RESEARCH AND        2018 ECOG-ACRIN      10/24/2018       $5,000.00
 EDUCATION FOUNDATION,    Fall Group
 INC.                     Meeting
------------------------------------------------------------------------
AMERICAN ASSOCIATION     AACR Special         10/28/2018      $25,000.00
 FOR CANCER RESEARCH      Conference on
                          Tumor Immunology
                          and Immunotherapy
------------------------------------------------------------------------
INTERNATIONAL            Best of 19th World   10/28/2018      $20,000.00
 ASSOCIATION FOR THE      Conference on
 STUDY OF LUNG CANCER     Lung Cancer
                          (WCLC)
------------------------------------------------------------------------
WASHINGTON UNIVERSITY    45th Annual          10/29/2018       $3,000.00
                          Washington
                          University Kilo
                          Diabetes
                          Symposium
------------------------------------------------------------------------
VIRGINIA BIOTECHNOLOGY   Medimmune            11/01/2018      $25,000.00
 ASSOCIATION              Chariman's Circle
                          Membership
------------------------------------------------------------------------
METABOLIC ENDOCRINE      16th Annual World    11/01/2018     $100,000.00
 EDUCATION FOUNDATION     congress on
                          Insulin
                          Resistance
                          Diabetes and
                          Cardiovascular
                          Disease (WCIRDC)
------------------------------------------------------------------------
MEDICAL LEARNING         PeerView Live--ISS   11/01/2018     $286,060.00
 INSTITUTE, INC.          at the Thoracic
                          Cancers
                          Symposium, "The
                          Present and
                          Future of
                          Immunotherapy as
                          a Key Component
                          of the Treatment
                          Arsenal for
                          Locally Advanced
                          and Earlier
                          Stages of Lung
                          Cancer: State of
                          the Science,
                          Practicalities,
                          and Implications
                          for Mult
------------------------------------------------------------------------
METABOLIC ENDOCRINE      CHF, the Next        11/01/2018     $150,705.00
 EDUCATION FOUNDATION     Frontier in
                          Diabetes: Do
                          SGLT2 Inhibitors
                          Have a Role in
                          Management and
                          Prevention?
------------------------------------------------------------------------
NATIONAL COMPREHENSIVE   ASCO and NCCN 2019   11/01/2018      $60,000.00
 CANCER NETWORK, INC.     ISS CCO: PARP
                          Inhibitors in
                          Breast Cancer:
                          Expert
                          Perspectives on
                          Clinical
                          Application and
                          Genetic Testing
------------------------------------------------------------------------
BOARD OF REGENTS OF THE  Grand Rounds         11/01/2018     $250,000.00
 UNIVERSITY OF NEBRASKA   series Bioascend:
                          2019 Ovarian
                          Community Grand
                          Rounds:
                          Incorporating
                          Recently Approved
                          Targeted Agents,
                          Emerging
                          Combinations, and
                          Genetic Testing
                          for the Optimal
                          Management of
                          Patients with
                          Ovarian Cancer
------------------------------------------------------------------------
NATIONAL ASSOCIATION OF  Webinars: PARP       11/01/2018     $150,000.00
 MANAGED CARE             Inhibition and
 PHYSICIANS, INC.         its Evolving Use
                          in the Treatment
                          of Cancers: What
                          Managed Care
                          Needs to Know for
                          Improved Clinical
                          and Economic
                          Outcomes
------------------------------------------------------------------------
JOHNS HOPKINS            FastForward Silver   11/05/2018      $25,000.00
 UNIVERSITY               Sponsorship
------------------------------------------------------------------------
ASSOCIATION FOR WOMEN    Innovation and       11/05/2018      $25,000.00
 IN SCIENCE               Inclusion Summit
------------------------------------------------------------------------
FOUNDATION FOR THE       2018 Biomarkers      11/05/2018      $10,000.00
 NATIONAL INSTITUTES OF   Consortium Cancer
 HEALTH                   Steering
                          Committee Annual
                          Scientific
                          Symposium
------------------------------------------------------------------------
MEDICAL LEARNING         PeerView Oncology--  11/06/2018     $324,340.00
 INSTITUTE, INC.          ISS at ASCO-SITC,
                          Seminars in
                          Immuno-Oncology,
                          ``III, II, I:
                          Addressing Unmet
                          Needs in Earlier
                          Stages of NSCLC
                          With
                          Immunotherapy''
                          (150205292)
------------------------------------------------------------------------
MEDICAL LEARNING         ISS at 2019          11/06/2018     $286,060.00
 INSTITUTE, INC.          Multidisciplinary
                          Thoracic Cancers
                          Symposium-
                          Refining Current
                          Practice and
                          Exploring New
                          Frontiers in EGFR-
                          Mutant NSCLC
                          (150205322)
------------------------------------------------------------------------
AMERICAN COLLEGE OF      Comparative          11/06/2018       $2,000.00
 VETERINARY               Pathologists in
 PATHOLOGISTS             Translational
                          Medicine
                          reception at the
                          2018 ACVP/ASVCP
                          Concurrent Annual
                          Meeting
------------------------------------------------------------------------
AMERICAN ASSOCATION OF   AAPS PharmSci 360    11/06/2018      $50,000.00
 PHARMACEUTICAL
 SCIENTISTS
------------------------------------------------------------------------
MAYO CLINIC ARIZONA      Mayo Clinic Cancer   11/07/2018       $5,000.00
                          Center Thoracic
                          Oncology Update
                          State of the Art
                          Evaluation and
                          Management of
                          Thoracic Cancers
------------------------------------------------------------------------
SOCIETY FOR              Case-based Forum:    11/07/2018      $20,000.00
 CARDIOVASCULAR           Individualizing
 ANGIOGRAPHY AND          Antithrombotic
 INTERVENTIONS            Therapies for PCI
 FOUNDATION               Patients
------------------------------------------------------------------------
UT HEALTH SAN ANTONIO    2019 Practical       11/07/2018       $5,000.00
                          Application of
                          New Agents in
                          Oncology
------------------------------------------------------------------------
AMERICAN SOCIETY FOR     2018 Best of ASTRO   11/07/2018      $10,000.00
 RADIATION ONCOLOGY
------------------------------------------------------------------------
PERSONALIZED MEDICINE    14th Annual          11/11/2018      $25,000.00
 COALITION                Personalized
                          Medicine
                          Conference
------------------------------------------------------------------------
ACLAM FOUNDATION         2018 ACLAM Grants    11/11/2018       $4,000.00
------------------------------------------------------------------------
ICAHN SCHOOL OF          LIVE Conference:     11/11/2018       $5,000.00
 MEDICINE AT MOUNT        3rd International
 SINAI                    Prostate Cancer
                          and Urologic
                          Oncology
                          Symposium
------------------------------------------------------------------------
AMERICAN SOCIETY FOR     2019                 11/11/2018      $50,000.00
 RADIATION ONCOLOGY       Multidisciplinary
                          Thoracic Cancers
                          Symposium
------------------------------------------------------------------------
CENTER FOR MEDICAL       Core Outcomes in     11/11/2018      $75,000.00
 TECHNOLOGY POLICY        Non-Alcoholic
                          Steatohepatitis
------------------------------------------------------------------------
THE UNIVERSITY OF TEXAS  Medical Oncology     11/11/2018      $10,000.00
 MD ANDERSON CANCER       and Hematology
 CENTER                   2019:
                          Multidisciplinary
                          Approaches that
                          Improve
                          Coordination of
                          Care
------------------------------------------------------------------------
NATIONAL COMPREHENSIVE   NCCN 2019 Nursing    11/11/2018      $30,000.00
 CANCER NETWORK, INC.     Program:
                          Advancing
                          Oncology NursingT
                          at the NCCN
                          Annual Conference
------------------------------------------------------------------------
NORTH AMERICAN 3R'S      Virtual Education    11/11/2018       $4,000.00
 COLLABORATIVE            Community (VEC)
                          Support
------------------------------------------------------------------------
COLLEGIUM                32nd Biennial        11/12/2018      $40,000.00
 INTERNATIONALE           Symposium of the
 ALLERGOLOGICUM           Collegium
                          Internationale
                          Allergologicum
------------------------------------------------------------------------
PENN STATE COLLEGE OF    ISS at AACR BTK      11/12/2018     $370,330.00
 MEDICINE                 Inhibition as an
                          Anti-Cancer
                          Strategy:
                          Exploring a Model
                          for Modern
                          Targeted Therapy
                          in Hematologic
                          Malignancies and
                          Beyond
                          (150205409)
------------------------------------------------------------------------
CLEVELAND CLINIC         Cleveland Clinic     11/12/2018       $5,000.00
 EDUCATIONAL FOUNDATION   Florida's 2nd
                          Annual San
                          Antonio Breast
                          Cancer Symposium
                          SABCS Official
                          Review Course
------------------------------------------------------------------------
MAYO CLINIC              Mayo Clinic          11/12/2018      $15,000.00
 JACKSONVILLE             Advances in
                          Breast Cancer
                          Management 2019
------------------------------------------------------------------------
LEUKEMIA RESEARCH        Hollis Brownstein    11/13/2018     $100,000.00
 FOUNDATION INC.          Research Grants
                          Program
------------------------------------------------------------------------
MEDICAL LEARNING         ISS at ONS- Taking   11/13/2018     $317,050.00
 INSTITUTE, INC.          Aim at B-Cell
                          Malignancies with
                          BTK Inhibitors:
                          Hematology/
                          Oncology Nurse
                          Perspectives and
                          Insights on
                          Clinical Care
                          (150205361)
------------------------------------------------------------------------
MEDSTAR HEALTH, INC.     Lung Cancer 2018:    11/15/2018       $5,000.00
                          Progress and
                          Future Directions
------------------------------------------------------------------------
NATIONAL KIDNEY          Research             11/18/2018      $28,800.00
 FOUNDATION               initiative to
                          extend the
                          analytical work
                          related to
                          evaluation of
                          clinical
                          endpoints
                          suitable for
                          early phase
                          trials in CKD
                          using the CKD-
                          Epidemiology
                          Consortium (CKD-
                          EPI)
------------------------------------------------------------------------
BOARD OF REGENTS OF THE  2019 Lymphoma        11/20/2018       $7,500.00
 UNIVERSITY OF NEBRASKA   Study Group
                          Hematology
                          Highlights A Post
                          ASH Review
------------------------------------------------------------------------
SCRIPPS HEALTH           39th Annual          11/20/2018      $25,000.00
                          Clinical
                          Hematology and
                          Oncology
                          Conference
------------------------------------------------------------------------
AMERICAN ACADEMY OF      Pharmacists' Role    11/25/2018      $49,800.00
 CME, INC.                in the
                          Comprehensive
                          Care of Acute
                          Coronary Syndrome
------------------------------------------------------------------------
PREVENTIVE               Connecting Heart     11/26/2018      $40,000.00
 CARDIOVASCULAR NURSES    Disease and
 ASSOCIATION              Diabetes-HCP Live
                          and On-Demand
                          Education
------------------------------------------------------------------------
UHS PROFESSIONAL         Women's Health       11/26/2018       $5,000.00
 EDUCATION PROGRAMS       2019
 INC. (DBA VCU HEALTH
 CONTINUING MEDICAL
 EDUCATION)
------------------------------------------------------------------------
CARDIOVASCULAR RESEARCH  25th Annual          11/26/2018      $15,000.00
 FOUNDATION               Interventional
                          Cardiology
                          Fellows Course
------------------------------------------------------------------------
CEDARS-SINAI MEDICAL     13th Annual Women    11/28/2018       $5,000.00
 CENTER                   and Ischemic
                          Heart Disease
                          Symposium
------------------------------------------------------------------------
SCRIPPS HEALTH           Dr. Richard Schatz   11/28/2018       $5,000.00
                          Interventional
                          Cardiology Summit
------------------------------------------------------------------------
KEYSTONE SYMPOSIA ON     2019 DNA             11/29/2018      $10,000.00
 MOLECULAR AND CELLULAR   Replication and
 BIOLOGY                  Genome
                          Instability: From
                          Mechanism to
                          Disease A1
------------------------------------------------------------------------
THE UNIVERSITY OF TEXAS  11th ANNUAL          11/29/2018      $50,000.00
 MD ANDERSON CANCER       HEMATOLOGIC
 CENTER                   MALIGNANCIES
                          DEMYSTIFIED: A
                          CRITICAL
                          APPRAISAL OF DATA
                          FROM 2018
------------------------------------------------------------------------
MEDSTAR WASHINGTON       Cardiovascular       11/29/2018      $25,000.00
 HOSPITAL CENTER          Research
                          Technologies,
                          (CRT) 2019
------------------------------------------------------------------------
CONQUER CANCER           2019 Conquer         12/02/2018      $40,000.00
 FOUNDATION OF THE        Cancer Foundation
 AMERICAN SOCIETY OF      of ASCO Merit
 CLINICAL ONCOLOGY        Awards
------------------------------------------------------------------------
NORTHWELL HEALTH         New York City--      12/02/2018      $20,000.00
                          Debates in
                          Interventional
                          Cardiology
------------------------------------------------------------------------
AMERICAN COLLEGE OF      New York             12/02/2018      $10,000.00
 CARDIOLOGY FOUNDATION    Cardiovascular
                          Symposium
------------------------------------------------------------------------
INTERNATIONAL            11th Biennial        12/02/2018      $25,000.00
 EOSINOPHIL SOCIETY,      Symposium
 INC.
------------------------------------------------------------------------
JOHNS HOPKINS            Grand Rounds         12/03/2018     $150,000.00
 UNIVERSITY SCHOOL OF     series MCM:15
 MEDICINE                 visting faculty
                          series: Novel
                          Targeted Agents
                          in the Management
                          of Recurrent
                          Advanced Ovarian
                          Cancer
------------------------------------------------------------------------
CONQUER CANCER           2019 Conquer         12/03/2018     $500,000.00
 FOUNDATION OF THE        Cancer Foundation
 AMERICAN SOCIETY OF      of ASCO Mission
 CLINICAL ONCOLOGY        Endowment
------------------------------------------------------------------------
AMERICAN ASSOCIATION     AACR-AstraZeneca     12/03/2018     $276,000.00
 FOR CANCER RESEARCH      Breast Cancer
                          Research
                          Fellowships
------------------------------------------------------------------------
AMERICAN ASSOCIATION     AACR-AstraZeneca     12/03/2018     $276,000.00
 FOR CANCER RESEARCH      Ovarian Cancer
                          Research
                          Fellowships (DNA
                          Damage Response)
------------------------------------------------------------------------
AMERICAN SOCIETY OF      ASH Bridge Grant     12/03/2018     $150,000.00
 HEMATOLOGY               Program
------------------------------------------------------------------------
GORDON RESEARCH          Gordon Research      12/03/2018       $4,000.00
 CONFERENCE               Conference:
                          Biotherapeutics
                          and Vaccines
                          Development
------------------------------------------------------------------------
INDIANA UNIVERSITY       Breast Cancer Year   12/03/2018       $5,000.00
                          in Review
------------------------------------------------------------------------
AMERICAN ASSOCIATION     AACR Annual          12/03/2018     $225,000.00
 FOR CANCER RESEARCH      Meeting 2019
------------------------------------------------------------------------
TEXAS HEART INSTITUTE    9th Annual Women's   12/03/2018       $3,000.00
                          Heart and
                          Vascular
                          Symposium: A New
                          Era in
                          Prevention,
                          Diagnosis and
                          Treatment
------------------------------------------------------------------------
AMERICAN COLLEGE OF      2018 Managing        12/03/2018     $150,000.00
 CARDIOLOGY FOUNDATION    Cardiovascular
                          Risk in Diabetes
                          Roundtable
------------------------------------------------------------------------
INTERNATIONAL            IASLC 19th           12/03/2018     $100,000.00
 ASSOCIATION FOR THE      Targeted
 STUDY OF LUNG CANCER     Therapies for
                          Lung Cancer
                          Meeting
------------------------------------------------------------------------
NORTH CAROLINA THORACIC  North Carolina       12/04/2018      $14,500.00
 SOCIETY                  Thoracic Society
                          Annual Meeting
------------------------------------------------------------------------
CONQUER CANCER           2019 Conquer         12/05/2018     $287,500.00
 FOUNDATION OF THE        Cancer Foundation
 AMERICAN SOCIETY OF      of ASCO Young
 CLINICAL ONCOLOGY        Investigator
                          Award (YIA)
------------------------------------------------------------------------
CONQUER CANCER           2019 Conquer         12/05/2018     $230,000.00
 FOUNDATION OF THE        Cancer Foundation
 AMERICAN SOCIETY OF      of ASCO Career
 CLINICAL ONCOLOGY        Development Award
                          (CDA)
------------------------------------------------------------------------
FRIENDS OF CANCER        2019 Friends of      12/05/2018     $200,000.00
 RESEARCH                 Cancer Research
                          Programs
------------------------------------------------------------------------
COLEGIO DE MEDICOS       Innovations in       12/06/2018      $10,000.00
 CIRUJANOS DE PUERTO      Medicine 2018
 RICO
------------------------------------------------------------------------
SOCIETY FOR              SITC's Cancer        12/06/2018     $150,000.00
 IMMUNOTHERAPY OF         Immunotherapy
 CANCER                   Winter School
------------------------------------------------------------------------
USF HEALTH PROFESSIONS   15th Annual          12/06/2018       $7,500.00
 CONFERENCING             Clinical
 CORPORATION              Breakthroughs and
                          Challenges in
                          Hematologic
                          Malignancies
------------------------------------------------------------------------
SOCIETY FOR              SITC's Cancer        12/09/2018     $100,000.00
 IMMUNOTHERAPY OF         Immunotherapy
 CANCER                   Guidelines
                          Project
------------------------------------------------------------------------
AMERICAN UROLOGICAL      Next Frontiers in    12/09/2018      $10,000.00
 ASSOCIATION              Urology 2019: a
                          Biennial AUA/JUA
                          Symposium
------------------------------------------------------------------------
HOSPITAL QUALITY         Update on NSTEMI     12/10/2018     $185,000.00
 FOUNDATION               Management for
                          Hospitalists
------------------------------------------------------------------------
CARDIOVASCULAR RESEARCH  DAPT Dilemmas: A     12/12/2018      $25,000.00
 FOUNDATION               Case-Based
                          Roundtable
                          Tutorial
------------------------------------------------------------------------
ST. DOMINIC-JACKSON      Neuroscience         12/12/2018       $5,000.00
 MEMORIAL HOSPITAL        Cardiovascular
                          Symposium
------------------------------------------------------------------------
HEART FAILURE SOCIETY    2019 Future          12/12/2018      $25,000.00
 OF AMERICA INC.          Leaders in Heart
                          Failure Symposium
------------------------------------------------------------------------
CONQUER CANCER           2019                 12/13/2018      $40,000.00
 FOUNDATION OF THE        Gastrointestinal
 AMERICAN SOCIETY OF      (GI) Cancers
 CLINICAL ONCOLOGY        Symposium:
                          Multidisciplinary
                          Treatment,
                          Personalized
                          Care, Optimal
                          Outcomes
------------------------------------------------------------------------
UNIVERSITY OF NEBRASKA   ONS 2019 ISS         12/13/2018     $150,000.00
 MEDICAL CENTER           Bioascend:
                          Patient and Nurse
                          Perspectives on
                          the Use of PARP
                          Inhibitors for
                          Ovarian Cancer:
                          Strategies for
                          Maximizing
                          Patient Outcomes
------------------------------------------------------------------------
THE UNIVERSITY OF TEXAS  2019 Oncologic       12/13/2018      $20,000.00
 MD ANDERSON CANCER       Emergency
 CENTER                   Medicine
                          Conference
------------------------------------------------------------------------
DUKE UNIVERSITY          4th Annual Duke      12/13/2018       $3,000.00
                          Heart Center/DCRI
                          Fellows'
                          Presentation
                          Skills Course
------------------------------------------------------------------------
FEDERATION OF AMERICAN   Acute Kidney         12/16/2018       $5,000.00
 SOCIETIES FOR            Injury: from
 EXPERIMENTAL BIOLOGY     beside to bench
                          (and back again)
------------------------------------------------------------------------
CONQUER CANCER           2019 ASCO-SITC       12/16/2018      $70,000.00
 FOUNDATION OF THE        Clinical Immuno-
 AMERICAN SOCIETY OF      Oncology
 CLINICAL ONCOLOGY        Symposium
------------------------------------------------------------------------
PENNYSLVANIA SOCIETY     2018 Educational     12/16/2018       $2,000.00
 FOR BIOMEDICAL           Programming
 RESEARCH                 Support
------------------------------------------------------------------------
AMERICAN DIABETES        Pathway to Stop      12/16/2018     $500,000.00
 ASSOCIATION              Diabetes
------------------------------------------------------------------------
MEDICAL LEARNING         ISS at ASCO GI--     12/17/2018      $37,500.00
 INSTITUTE, INC.          Breaking the
                          Paradox:
                          Expanding Options
                          and New Questions
                          in HCC Management
                          (150205289)
------------------------------------------------------------------------
C DAVIS AND S THOMPSON   Corporate            12/17/2018       $2,000.00
 DVM FOUNDATION           Membership
------------------------------------------------------------------------
MIDWINTER CONFERENCE OF  58th Midwinter       12/18/2018       $5,000.00
 IMMUOLOGISTS             Conference of
                          Immunologists
------------------------------------------------------------------------
SOCIETY FOR              SITC General         12/19/2018       $3,000.00
 IMMUNOTHERAPY OF         Society
 CANCER
------------------------------------------------------------------------
NATIONAL ACADEMY OF      Roundtable in        12/20/2018       $4,000.00
 SCIENCES                 Science and
                          Welfare of
                          Laboratory Animal
                          Use
------------------------------------------------------------------------
MIT                      Koch Institute       12/23/2018       $5,000.00
                          2019 Immune
                          Engineering
                          Symposium
------------------------------------------------------------------------
NATIONAL KIDNEY          The Role of the      01/03/2019     $100,000.00
 FOUNDATION               Kidney and SGLT2
                          in Glucose
                          Homeostasis and
                          Kidney Disease: A
                          Scientific
                          Workshop
                          Sponsored by the
                          National Kidney
                          Foundation
------------------------------------------------------------------------
AMERICAN ACADEMY OF      AAAAI Foundation     01/03/2019     $150,000.00
 ALLERGY, ASTHMA AND      2019 Lectureship
 IMMUNOLOGY FOUNDATION,   Series
 INC.
------------------------------------------------------------------------
NATIONAL JEWISH HEALTH   15th Annual          01/03/2019     $299,856.00
                          Respiratory
                          Disease Young
                          Investigators'
                          Forum
------------------------------------------------------------------------
MEDICAL LEARNING         ONS 2019 ISS         01/07/2019     $250,000.00
 INSTITUTE INC.           Peerview:,
                          ``Realizing the
                          Promise of PARP
                          Inhibitors in
                          Solid Tumor
                          Therapy Guiding
                          Oncology Nurses
                          on the Advances
                          and Challenges''
                          (150205359)
------------------------------------------------------------------------
AMERICAN SOCIETY OF      Kidney Health        01/14/2019      $30,000.00
 NEPHROLOGY               Initiative
------------------------------------------------------------------------
MELANOMA RESEARCH        Melanoma Research    01/14/2019      $10,000.00
 ALLIANCE                 Alliance 11th
                          Annual Scientific
                          Retreat
------------------------------------------------------------------------
METABOLIC ENDOCRINE      3rd Annual Heart     01/15/2019     $100,000.00
 EDUCATION FOUNDATION     in Diabetes (HiD)
------------------------------------------------------------------------
COLD SPRING HARBOR       Integrated control   01/16/2019      $10,000.00
 LABORATORY               of feeding and
                          energy balance by
                          hypothalamic and
                          hindbrain
                          circuits
------------------------------------------------------------------------
NEW YORK UNIVERSITY      XXIV Conference on   01/16/2019       $5,000.00
                          the Chemistry of
                          the Organic Solid
                          State
------------------------------------------------------------------------
NATIONAL JEWISH HEALTH   41st Annual          01/22/2019      $10,000.00
                          National Jewish
                          Health Pulmonary
                          and Allergy
                          Update
------------------------------------------------------------------------
MEDICAL LEARNING         ISS at AATS 2019     01/22/2019     $302,760.00
 INSTITUTE INC.           Broadening
                          Horizons:The
                          Expanding Role of
                          Immunotherapy in
                          Locally Advanced
                          and Earlier
                          Stages of Lung
                          Cancer
                          (150205422)
------------------------------------------------------------------------
MEDICAL LEARNING         CAP Chapter          01/24/2019     $414,050.00
 INSTITUTE, INC.          Meetings:
                          Molecular Testing
                          for EGFR
                          Mutations in the
                          Context of a
                          Changing
                          Treatment
                          Landscape,
                          Evolving Testing
                          Options, and New
                          Guidelines What
                          Do Pathologists
                          Need to Know and
                          Do? (150205307)
------------------------------------------------------------------------
LUNGEVITY FOUNDATION     LUNGevity            02/03/2019      $10,000.00
                          Foundation
                          Nursing and Nurse
                          Navigator
                          Roundtable
------------------------------------------------------------------------
REGENTS OF UC SAN DIEGO  2nd Annual Multi-    02/04/2019      $25,000.00
                          Disciplinary Head
                          and Neck Cancer
                          Conference-
                          Maximizing Speech
                          and Swallowing
                          Outcomes in
                          Patients
                          Undergoing
                          Radiation
                          Therapy: We're in
                          This Together
------------------------------------------------------------------------
UNIVERSITY OF KANSAS     2018 San Antonio     02/06/2019       $5,000.00
 MEDICAL CENTER           Breast Cancer
                          Symposium Review
------------------------------------------------------------------------
NATIONAL ASSOCIATION OF  Individualizing      02/06/2019      $22,500.00
 MANAGED CARE             Treatment in the
 PHYSICIANS, INC.         Management of
                          Advanced Breast
                          Cancer: How Novel
                          Therapies Are
                          Changing the
                          Treatment
                          Paradigm
------------------------------------------------------------------------
NATIONAL ASSOCIATION OF  Integrating New      02/06/2019      $22,500.00
 MANAGED CARE             and Emerging
 PHYSICIANS, INC.         Targeted
                          Therapies into
                          the Treatment
                          Paradigm in
                          Ovarian Cancer:
                          Expert Strategies
                          for Improved
                          Patient Outcomes
------------------------------------------------------------------------
FEDERATION OF AMERICAN   Mitochondrial        02/07/2019      $10,000.00
 SOCIETIES FOR            Biogenesis and
 EXPERIMENTAL BIOLOGY     Dynamics in
                          Health and
                          Disease
------------------------------------------------------------------------
NATIONAL JEWISH HEALTH   Impact of            02/07/2019      $64,925.00
                          Educational
                          Program on the
                          Career
                          Development of
                          Physician
                          Scientists;
                          Outcomes from 14
                          years of the
                          Annual
                          Respiratory
                          Disease Young
                          Investigators'
                          Forum--An Article
                          for Publication
------------------------------------------------------------------------
NYU SCHOOL OF MEDICINE   Asthma Airways and   02/10/2019      $20,000.00
                          the Environment
------------------------------------------------------------------------
MEDSTAR HEALTH           Mid-Atlantic         02/10/2019      $50,000.00
                          Nephrology Young
                          Investigators
                          Forum
------------------------------------------------------------------------
SOCIETY OF GYNECOLOGIC   SGO 2019 Annual      02/10/2019      $62,500.00
 ONCOLOGY                 Meeting on
                          Women's Cancer
------------------------------------------------------------------------
COLUMBIA UNIVERSITY      Heart Disease and    02/11/2019       $7,500.00
 DEPARTMENT OF SURGERY    Women
------------------------------------------------------------------------
AMERICAN DIABETES        66th Advanced        02/11/2019      $40,000.00
 ASSOCIATION              Postgraduate
                          Course
------------------------------------------------------------------------
NATIONAL KIDNEY          Hypoxia-Inducible    02/11/2019     $100,000.00
 FOUNDATION               Factor
                          Stabilization as
                          an Emerging
                          Therapy for CKD
                          Related Anemia A
                          Scientific
                          Workshop
                          Sponsored by the
                          National Kidney
                          Foundation
------------------------------------------------------------------------
NATIONAL COMPREHENSIVE   2019-2020 Monthly    02/13/2019      $25,000.00
 CANCER NETWORK, INC.     Oncology Tumor
                          Boards: A
                          Multidisciplinary
                          Approach to
                          Individualized
                          Patient Care
------------------------------------------------------------------------
NATIONAL COMPREHENSIVE   2019-2020 Monthly    02/13/2019      $25,000.00
 CANCER NETWORK, INC.     Oncology Tumor
                          Boards: A
                          Multidisciplinary
                          Approach to
                          Individualized
                          Patient Care
------------------------------------------------------------------------
THE SOCIETY OF SURGICAL  SSO 2019 Annual      02/14/2019       $5,000.00
 ONCOLOGY                 Cancer Symposium
------------------------------------------------------------------------
ONCOLOGY NURSING         ONS Evidence-Based   02/17/2019     $293,500.00
 SOCIETY                  Practice
                          Improvement
                          Project:
                          Constipation
------------------------------------------------------------------------
THE UNIVERSITY OF        16th Annual          02/17/2019      $50,000.00
 CHICAGO                  International
                          Ultmann Chicago
                          Lymphoma
                          Symposium
------------------------------------------------------------------------
HOUSTON METHODIST        Heart of a Woman     02/17/2019       $3,000.00
 HOSPITAL
------------------------------------------------------------------------
HEMATOLOGY/ONCOLOGY      HOPA 15th Annual     02/18/2019      $35,000.00
 PHARMACY ASSOCIATION     Conference
------------------------------------------------------------------------
BAYLOR SCOTT AND WHITE   8th Annual           02/18/2019      $10,000.00
 HEALTH                   Symposium on
                          Current
                          Strategies in the
                          Treatment of
                          Multiple Myeloma,
                          Leukemia,
                          Hodgkin's
                          Lymphoma and B-
                          cell Non-
                          Hodgkin's
                          Lymphoma
------------------------------------------------------------------------
USF HEALTH PROFESSIONS   CARDIOVASCULAR AND   02/18/2019     $247,330.00
 CONFERENCING             RENAL
 CORPORATION              COMPLICATIONS IN
                          T2DM: Roles of
                          Physician
                          Assistants and
                          Nurse
                          Practitioners in
                          Patient
                          Management
------------------------------------------------------------------------
NATIONAL ASSOCIATION OF  New Horizons in      02/18/2019      $35,000.00
 MANAGED CARE             the Treatment and
 PHYSICIANS, INC.         Management of B-
                          Cell Non-Hodgkin
                          Lymphoma: A
                          Closer Look at
                          the Role of
                          Emerging Targeted
                          Therapies
------------------------------------------------------------------------
ONCOLOGY NURSING         ONS 44th Annual      02/18/2019      $50,000.00
 SOCIETY                  Congress and
                          Regional
                          Workshops
------------------------------------------------------------------------
MEDICAL LEARNING         PeerView inVision:   02/19/2019     $122,250.00
 INSTITUTE INC.           ``New Frontiers
                          in Managing Heart
                          Failure: Are
                          SGLT2 Inhibitors
                          the Next Leap
                          Forward in
                          Optimizing
                          Patient Care?''
                          (150205455)
------------------------------------------------------------------------
NATIONAL COMPREHENSIVE   NCCN 2019 Annual     02/19/2019      $75,000.00
 CANCER NETWORK, INC.     Conference:
                          Improving the
                          Quality,
                          Effectiveness,
                          and Efficiency of
                          Cancer CareTM
------------------------------------------------------------------------
ACS DIVISION OF          257th ACS National   02/19/2019       $2,000.00
 MEDICINAL CHEMISTRY      Meeting
------------------------------------------------------------------------
ASSOCIATION FOR          TARC Targeting DNA   02/19/2019     $125,000.00
 MOLECULAR PATHOLOGY      Repair Pathways:
                          Current and
                          Future
                          Implications of
                          PARP Inhibitors
------------------------------------------------------------------------
COLUMBIA UNIVERSITY      Pancreas Symposium   02/20/2019       $3,000.00
 DEPARTMENT OF SURGERY    2019: Current
                          Controversies in
                          Benign and
                          Malignant
                          Pancreatic
                          Disease
------------------------------------------------------------------------
CONQUER CANCER           2019 ASCO Annual     02/20/2019      $30,000.00
 FOUNDATION OF THE        Meeting Breast
 AMERICAN SOCIETY OF      Cancer Track
 CLINICAL ONCOLOGY
------------------------------------------------------------------------
ST. JOSEPH REGIONAL      Annual               02/21/2019       $1,000.00
 HEALTH NETWORK           Cardiovascular
                          Symposium
------------------------------------------------------------------------
ANNENBERG CENTER FOR     Master Class for     02/21/2019      $25,000.00
 HEALTH SCIENCES AT       Oncologists 2019--
 EISENHOWER               Women's Cancer
                          Track
------------------------------------------------------------------------
ANNENBERG CENTER FOR     Master Class for     02/21/2019      $25,000.00
 HEALTH SCIENCES AT       Oncologists 2019--
 EISENHOWER               Hematologic
                          Malignancies
                          Track
------------------------------------------------------------------------
AMERICAN COLLEGE OF      Achieving            02/24/2019       $1,500.00
 PHYSICIANS; PUERTO       Excellence in
 RICO CHAPTER             Patient Care
                          American College
                          of Physician
                          Annual Meeting
                          and Internal
                          Medicine Update
                          and Board Review
------------------------------------------------------------------------
MEDICAL LEARNING         PeerView Video in    02/25/2019      $95,975.00
 INSTITUTE INC.           Exchange
                          Navigating
                          Clinical
                          Challenges to
                          Maximize the
                          Benefits and
                          Minimize the
                          Risks of Cancer
                          Immunotherapies
                          (150204478)
------------------------------------------------------------------------
COLUMBIA UNIVERSITY      Breast Cancer        02/26/2019       $2,000.00
 DEPARTMENT OF SURGERY    Management 2019
------------------------------------------------------------------------
HOLY CROSS HOSPITAL      Updates in the       02/28/2019       $2,000.00
 INC.                     Treatment of
                          Common Cancers:
                          Lung,
                          Gastrointestinal,
                          GYN, and Breast
------------------------------------------------------------------------
HOLY CROSS HOSPITAL      Updates in the       02/28/2019       $2,000.00
 INC.                     Treatment of
                          Common Cancers:
                          Lung,
                          Gastrointestinal,
                          GYN, and Breast
------------------------------------------------------------------------
NATIONAL KIDNEY          Chronic              03/01/2019     $257,085.00
 FOUNDATION               Hyperkalemia
                          Management and
                          Outcomes in CKD
------------------------------------------------------------------------
AMERICAN ACADEMY OF      Crucial              03/03/2019      $99,990.00
 CME, INC.                Conversations in
                          Nephrology: PHD
                          Inhibition as an
                          Emerging Approach
                          to Treating CKD
                          Anemia
------------------------------------------------------------------------
UNIVERSITY OF ROCHESTER  20th Annual          03/03/2019       $6,500.00
                          Diabetes
                          Conference:
                          Current
                          Treatments for
                          Diabetes
                          Complications
------------------------------------------------------------------------
CLEVELAND CLINIC         Advanced             03/03/2019      $10,000.00
 EDUCATIONAL FOUNDATION   Diagnostic
                          Bronchoscopy
                          Workshop
------------------------------------------------------------------------
PREVENTIVE               Cardiovascular       03/03/2019      $50,000.00
 CARDIOVASCULAR NURSES    Risk Reduction:
 ASSOCIATION              25th
                          Cardiovascular
                          Nursing Symposium
                          Opening Session
------------------------------------------------------------------------
PENN STATE COLLEGE OF    An Update on SGLT2   03/03/2019     $142,430.00
 MEDICINE                 Inhibition for
                          the Prevention
                          and Treatment of
                          Kidney Disease in
                          Patients with
                          Type 2 Diabetes
                          (150205286)
------------------------------------------------------------------------
REGENTS OF THE           Making the           03/03/2019     $200,000.00
 UNIVERSITY OF            Connection: A
 CALIFORNIA, SAN DIEGO    Comprehensive
                          Strategy on the
                          Modern Management
                          of Type 1 and
                          Type 2 Diabetes
                          2019
------------------------------------------------------------------------
ANNENBERG CENTER FOR     From Inquiry to      03/03/2019      $50,000.00
 HEALTH SCIENCES AT       Investigation to
 EISENHOWER               Insight (I3):
                          Clinical Clarity
                          in Non-Small Cell
                          Lung Cancer--The
                          2019 JADPRO Lung
                          Cancer Conference
------------------------------------------------------------------------
NATIONAL ASSOCIATION OF  Advances in the      03/03/2019      $30,000.00
 MANAGED CARE             Management of
 PHYSICIANS, INC.         Acute Coronary
                          Syndrome (ACS):
                          Updated Guideline
                          Recommendations
                          for Dual
                          Antiplatelet
                          Therapy
------------------------------------------------------------------------
EASTERN VIRGINIA         Turning the Tide     03/03/2019       $5,000.00
 MEDICAL SCHOOL           on Diabetes 2019
------------------------------------------------------------------------
AMERICAN ACADEMY OF      Foundations of       03/04/2019     $200,000.00
 ALLERGY ASTHMA AND       Asthma Management
 IMMUNOLOGY
------------------------------------------------------------------------
KEYSTONE SYMPOSIA ON     2019 Cancer          03/04/2019       $5,000.00
 MOLECULAR AND CELLULAR   Immunotherapy:
 BIOLOGY                  Mechanistic
                          Insights to
                          Improve Clinical
                          Benefit
------------------------------------------------------------------------
METABOLIC ENDOCRINE      The Primary          03/04/2019     $154,110.00
 EDUCATION FOUNDATION     Prevention of CHF
                          and CKD in
                          Diabetes
                          Satellite
                          Symposium
------------------------------------------------------------------------
THE CHEST FOUNDATION     2019 CHEST           03/04/2019      $35,000.00
                          Foundation
                          Research Award in
                          Severe Asthma
------------------------------------------------------------------------
MEDICAL LEARNING         PeerView Live at     03/04/2019      $90,000.00
 INSTITUTE INC.           USCAP 2019,
                          Clinical Advances
                          in Cancer
                          Immunotherapies,
                          Biomarkers, and
                          Testing:
                          Implications for
                          Pathologists at
                          the Forefront of
                          the Emerging
                          Precision
                          Oncology Era
                          (150205529)
------------------------------------------------------------------------
AMERICAN NEPHROLOGY      The CKD Patient      03/05/2019      $61,500.00
 NURSES ASSOCIATION       with
 (ANNA)                   Hyperkalemia:
                          Nephrology Nurses
                          Evidence Based
                          Care
------------------------------------------------------------------------
NATIONAL ASSOCIATION OF  Improving Clinical   03/05/2019      $35,000.00
 MANAGED CARE             and Economic
 PHYSICIANS, INC.         Outcomes with
                          Personalized
                          Treatment in the
                          Management of
                          Advanced Non-
                          Small Cell Lung
                          Cancer (NSCLC)
------------------------------------------------------------------------
DUKE UNIVERSITY          The Southeastern     03/06/2019       $2,500.00
                          Fellows Research
                          Skills and
                          Training Workshop
------------------------------------------------------------------------
NATIONAL COMPREHENSIVE   NCCN 2019 Oncology   03/06/2019      $10,000.00
 CANCER NETWORK, INC.     Fellows Program:
                          New Horizons in
                          Quality Cancer
                          CareT at the NCCN
                          Annual Conference
------------------------------------------------------------------------
UNIVERSITY OF            Allergy Fellowship   03/06/2019      $40,000.00
 WASHINGTON SCHOOL OF
 MEDICINE
------------------------------------------------------------------------
DREXEL MEDICINE          Updates In Women's   03/06/2019       $2,000.00
                          Health 2109
------------------------------------------------------------------------
MEDICAL LEARNING         Addressing Unmet     03/06/2019     $122,250.00
 INSTITUTE INC.           Needs in Managing
                          Anemia in Chronic
                          Kidney Disease: A
                          Closer Look at
                          the Clinical
                          Potential of HIF-
                          PH Inhibitors
                          (150205556)
------------------------------------------------------------------------
SIDNEY KIMMEL MEDICAL    7th Annual Lung      03/06/2019       $2,500.00
 COLLEGE AT THOMAS        Cancer Symposium
 JEFFERSON UNIVERSITY
------------------------------------------------------------------------
MEDICAL LEARNING         ASCO 2019 peer       03/10/2019      $30,000.00
 INSTITUTE INC.           view Stories from
                          the Pancreatic
                          Cancer CaseBook:
                          Taking the Road
                          to Improved
                          Outcomes with
                          Modern
                          Therapeutic
                          Concepts and
                          Innovative
                          Treatments
                          (150205416)
------------------------------------------------------------------------
AMERICAN COLLEGE OF      GKCAS 2019 Annual    03/10/2019       $3,000.00
 ALLERGY, ASTHMA AND      Meeting
 IMMUNOLOGY
------------------------------------------------------------------------
REGENTS OF THE           13th International   03/10/2019      $25,000.00
 UNIVERSITY OF            Congress on
 CALIFORNIA               Systemic Lupus
                          Erythematosus
                          (LUPUS 2019)
------------------------------------------------------------------------
NATIONAL COMPREHENSIVE   Support for NCCN     03/11/2019      $60,000.00
 CANCER NETWORK, INC.     Distribution of
                          the NCCN Clinical
                          Practice
                          Guidelines in
                          Oncology (NCCN
                          Guidelinesr) for
                          Management of
                          Immunotherapy-
                          Related
                          Toxicities Pocket
                          Guides
------------------------------------------------------------------------
AMERICAN UROLOGICAL      Bladder Cancer in    03/11/2019      $15,000.00
 ASSOCIATION              Women:
                          Identifying
                          Research Needs to
                          Improve Diagnosis
                          and Treatment A
                          Johns Hopkins
                          Greenberg Bladder
                          Cancer Institute/
                          American
                          Urological
                          Association
                          Translational
                          Research
                          Collaboration
------------------------------------------------------------------------
GORDON RESEARCH          2019 Multidrug       03/11/2019       $2,500.00
 CONFERENCES              Efflux Systems
                          Gordon Research
                          Conference
------------------------------------------------------------------------
NATIONAL KIDNEY          14th Annual Young    03/12/2019      $50,000.00
 FOUNDATION               Investigator's
                          Forum
------------------------------------------------------------------------
AMERICAN COLLEGE OF      Lung Cancer          03/12/2019      $25,000.00
 CHEST PHYSICIANS         Screening
                          Decision
                          Counselor and
                          Navigator
                          Training
------------------------------------------------------------------------
SOCIETY OF               SIR Annual           03/13/2019      $12,500.00
 INTERVENTIONAL           Scientific
 RADIOLOGY                Meeting
------------------------------------------------------------------------
ECOG RESEARCH AND        ECOG-ACRIN Spring    03/13/2019       $5,000.00
 EDUCATION FOUNDATION,    2019 Group
 INC.                     Meeting
------------------------------------------------------------------------
MEDSTAR HEALTH, INC.     Kidney and Bladder   03/14/2019      $10,000.00
                          Cancers 2019
------------------------------------------------------------------------
AMERICAN COLLEGE OF      ACC Annual           03/14/2019      $50,000.00
 CARDIOLOGY FOUNDATION    Scientific
                          Session
------------------------------------------------------------------------
SAINT FRANCIS HOSPITAL   55th Annual Robert   03/14/2019       $5,000.00
 AND MEDICAL CENTER       M. Jeresaty, MD
                          Cardiovascular
                          Symposium
------------------------------------------------------------------------
CARDIOVASCULAR RESEARCH  A New Beat:          03/14/2019      $25,000.00
 FOUNDATION               Improving
                          Cardiovascular
                          Care in Women and
                          Minorities
------------------------------------------------------------------------
GORDON RESEARCH          Therapeutically      03/14/2019       $2,500.00
 CONFENCE                 Targeted Small
                          Molecules and
                          Enabling
                          Technologies in
                          Drug Discovery
------------------------------------------------------------------------
NATIONAL COMPREHENSIVE   Support for NCCN     03/14/2019      $25,000.00
 CANCER NETWORK           Distribution of
                          the NCCN Clinical
                          Practice
                          Guidelines in
                          Oncology (NCCN
                          Guidelinesr) for
                          Breast Cancer
                          Pocket Guides
------------------------------------------------------------------------
NORTHWELL HEALTH         1st Annual Heart     03/17/2019      $15,000.00
                          of Prevention
                          Symposium:
                          Updates on
                          Cardiovascular
                          Disease
                          Prevention With a
                          Focus on Women's
                          Heart Health
------------------------------------------------------------------------
AMERICAN THORACIC        ATS 2019 Fellows     03/17/2019      $10,000.00
 SOCIETY INC.             Track Symposium
------------------------------------------------------------------------
SOCIETY FOR              SITC's PD-L1         03/17/2019      $35,000.00
 IMMUNOTHERAPY OF         Resistance
 CANCER                   Definition
                          Project
------------------------------------------------------------------------
CITY OF HOPE             8th Annual           03/17/2019      $10,000.00
                          Clinical Cancer
                          Genetics and
                          Genomics
                          Conference; From
                          Exceptionalism to
                          Exceptional Care:
                          Mainstreaming
                          Genomic Medicine
                          in Clinical
                          Practice
------------------------------------------------------------------------
FEDERATION OF AMERICAN   2019 FASEB SRC on    03/18/2019       $5,000.00
 SOCIETIES FOR            Intracellular RNA
 EXPERIMENTAL BIOLOGY     localization and
                          local translation
------------------------------------------------------------------------
FOUNDATION FOR HEART     23rd Annual Heart    03/18/2019      $10,000.00
 FAILURE EDUCATION,       Failure-An Update
 INC.                     on Therapy
------------------------------------------------------------------------
PURDUE UNIVERSITY        Type 2 Diabetes      03/19/2019      $75,000.00
                          Mellitus and
                          Heart Failure:
                          Screening,
                          Diagnosis, and
                          Management
------------------------------------------------------------------------
ASTHMA AND ALLERGY       ``Wheezin, Sneezin   03/19/2019      $10,000.00
 FOUNDATION OF AMERICA--  and Itchin in
 ALASKA CHAPTER           Alaska''
------------------------------------------------------------------------
AMERICAN RADIUM SOCIETY  101st Annual         03/19/2019      $25,000.00
                          Meeting
------------------------------------------------------------------------
NATIONAL KIDNEY          Anemia in Chronic    03/19/2019     $257,085.00
 FOUNDATION               Kidney Disease:
                          Arming Clinicians
                          with Meaningful
                          Solutions
------------------------------------------------------------------------
AMERICAN UROLOGICAL      The Evolving Role    03/19/2019      $25,000.00
 ASSOCIATION EDUCATION    of the Urologist
 AND RESEARCH, INC.       in Advanced
                          Castration
                          Dependent
                          Prostate Cancer:
                          a Guidelines and
                          Case-based
                          Discussion
------------------------------------------------------------------------
NATIONAL COMPREHENSIVE   Emerging Issues in   03/20/2019      $25,000.00
 CANCER NETWORK, INC.     Oncology--Ensurin
                          g Access to, and
                          Delivery of,
                          Innovative
                          Therapies and
                          Patient Centered
                          Care in Oncology
------------------------------------------------------------------------
ACS DIVISION OF          257th ACS National   03/20/2019       $5,000.00
 BIOCHEMICAL TECHNOLOGY   Meeting and
                          Exposition (BIOT
                          Division)
------------------------------------------------------------------------
Worksheet: Grants 2014 to Mar 20 2019


                                                                       Appendix B
--------------------------------------------------------------------------------------------------------------------------------------------------------
   Product     Q114   Q214   Q314   Q414   Q115   Q215   Q315   Q415   Q116   Q216   Q316   Q416   Q117   Q217   Q317   Q417   Q118   Q218   Q318   Q418
--------------------------------------------------------------------------------------------------------------------------------------------------------
FARXIGA                                                                                               X      X      X      X      X      X      X      X
--------------------------------------------------------------------------------------------------------------------------------------------------------
ONGLYZA                                       X      X      X      X      X      X      X      X      X      X      X      X      X      X      X      X
--------------------------------------------------------------------------------------------------------------------------------------------------------
KOMBIGLYZE                                                         X      X      X      X      X      X      X      X      X      X      X      X      X
--------------------------------------------------------------------------------------------------------------------------------------------------------
SYMBICORT                                                                 X      X      X      X      X      X      X      X      X      X      X      X
--------------------------------------------------------------------------------------------------------------------------------------------------------
PULMICORT                                                                                             X      X      X      X      X      X      X      X
 FLEXHALER
--------------------------------------------------------------------------------------------------------------------------------------------------------
NEXIUM OS         X      X      X      X      X      X      X      X      X      X      X      X      X      X      X      X      X      X      X      X
--------------------------------------------------------------------------------------------------------------------------------------------------------
NEXIUM XSULE      X      X      X      X      X      X      X      X      X      X      X      X      X      X             X      X      X
--------------------------------------------------------------------------------------------------------------------------------------------------------
CRESTOR           X      X      X      X      X      X      X      X      X      X      X      X      X      X      X      X      X      X      X      X
--------------------------------------------------------------------------------------------------------------------------------------------------------
BYETTA                                        X      X      X      X      X      X      X      X      X      X      X      X      X      X      X      X
--------------------------------------------------------------------------------------------------------------------------------------------------------
BYDUREON                                                                                                                          X      X      X      X
--------------------------------------------------------------------------------------------------------------------------------------------------------
SYMLIN            X      X      X      X      X      X      X      X      X      X      X      X      X      X      X      X      X      X      X      X
--------------------------------------------------------------------------------------------------------------------------------------------------------
TUDORZA                                                                                                                           X      X      X      X
--------------------------------------------------------------------------------------------------------------------------------------------------------
X URA Capped at AMP


                               Appendix C
------------------------------------------------------------------------
        Product                 MPD Plan             Effective Dates
------------------------------------------------------------------------
                        Abarca                           1/1/18-12/31/19
                       -------------------------------------------------
                        Envision                         1/1/18-12/31/18
                       -------------------------------------------------
Byetta                  Express Scripts                  4/1/18-12/31/19
                       -------------------------------------------------
                        Health Delegates                 1/1/18-12/31/18
                       -------------------------------------------------
                        MedImpact                        1/1/19-12/31/19
                       -------------------------------------------------
                        SIS                              1/1/18-12/31/19
------------------------------------------------------------------------
                        Abarca                           1/1/16-12/31/16
                       -------------------------------------------------
                        Blue Shield of CA        7/1/15-12/31/16; 5/2/16-
                                                                12/31/16
                       -------------------------------------------------
                        Emblem Health            1/1/15-12/31/15; 1/1/16-
                                                                12/31/16
                       -------------------------------------------------
                        Envision                         1/1/17-12/31/17
                       -------------------------------------------------
                        Express Scripts                  5/2/16-12/31/19
                       -------------------------------------------------
                        Florida Health                   1/1/14-12/31/16
                       -------------------------------------------------
                        Health Alliance Medical          1/1/15-12/31/16
                         Plan
                       -------------------------------------------------
                        Health Partners Plans            1/1/15-12/31/16
                       -------------------------------------------------
                        Healthspring                     4/1/15-12/31/15
                       -------------------------------------------------
                        Highmark                         7/1/14-12/31/16
                       -------------------------------------------------
                        Humana                   1/1/15-12/31/16; 5/1/16-
                                                  7/30/16; 8/1/2016-P12/
                                                                   31/16
                       -------------------------------------------------
Crestor                 IHA                              1/1/15-12/31/16
                       -------------------------------------------------
                        MedImpact                          1/1/15-5/1/16
                       -------------------------------------------------
                        Navitus                          1/1/15-12/31/16
                       -------------------------------------------------
                        OptumRx                          7/1/16-12/31/17
                       -------------------------------------------------
                        Perform Rx                      10/1/15-12/31/16
                       -------------------------------------------------
                        Pharm. Tech                      1/1/15-12/31/16
                       -------------------------------------------------
                        Prime Therapeutics               5/2/16-12/31/16
                       -------------------------------------------------
                        SelectHealth                     1/1/15-12/31/16
                       -------------------------------------------------
                        SilverScript                     7/1/14-12/31/16
                       -------------------------------------------------
                        SIS                              1/1/15-12/31/16
                       -------------------------------------------------
                        Ventegra                         1/1/15-12/31/16
                       -------------------------------------------------
                        WellCare                         1/1/15-12/31/16
------------------------------------------------------------------------
                        Envision                 1/1/17-12/31/17; 1/1/18-
                                                                12/31/18
                       -------------------------------------------------
                        Express Scripts                  1/1/16-12/31/19
                       -------------------------------------------------
                        Harvard Pilgrim                  1/1/14-12/31/14
                       -------------------------------------------------
                        Health Alliance Medical          1/1/14-12/31/14
                         Plan
                       -------------------------------------------------
                        Healthspring                     4/1/15-12/31/15
                       -------------------------------------------------
                        Highmark                         7/1/14-12/31/16
                       -------------------------------------------------
Nexium                  Humana                   1/1/14-12/31/14; 1/1/15-
                                                                12/31/16
                       -------------------------------------------------
                        Navitus                  1/1/14-1/31/14; 1/1/15-
                                                                12/31/16
                       -------------------------------------------------
                        Optum Rx                         1/1/14-12/31/18
                       -------------------------------------------------
                        Prime Therapeutics               1/1/14-12/31/14
                       -------------------------------------------------
                        Scott & White                    1/1/14-12/31/14
                       -------------------------------------------------
                        SilverScript                     7/1/14-12/31/16
                       -------------------------------------------------
                        WellCare                         1/1/15-12/31/16
------------------------------------------------------------------------
                        Abarca                           1/1/16-12/31/16
                       -------------------------------------------------
                        Blue Shield of CA                1/1/15-12/31/16
                       -------------------------------------------------
                        Emblem Health            1/1/15-12/31/15; 1/1/16-
                                                                12/31/16
                       -------------------------------------------------
                        Envision                 1/1/17-12/31/17; 1/1/18-
                                                                12/31/18
                       -------------------------------------------------
                        Health Partners Plans            1/1/15-12/31/16
                       -------------------------------------------------
                        Healthspring                     4/1/15-12/31/15
                       -------------------------------------------------
Seroquel                Highmark                         7/1/14-12/31/16
                       -------------------------------------------------
                        Humana                           1/1/15-12/31/16
                       -------------------------------------------------
                        IHA                              1/1/15-12/31/16
                       -------------------------------------------------
                        Navitus                  1/1/15-12/31/16; 1/1/17-
                                                                12/31/19
                       -------------------------------------------------
                        Perform Rx                      10/1/15-12/31/16
                       -------------------------------------------------
                        Pharm. Tech              1/1/15-12/31/16; 1/1/18-
                                                                12/31/18
                       -------------------------------------------------
                        SelectHealth                     1/1/17-12/31/18
                       -------------------------------------------------
                        SIS                              1/1/15-12/31/16
------------------------------------------------------------------------
                        Health Alliance Medical          1/1/15-12/31/16
                         Plan
                       -------------------------------------------------
Seroquel XR             SilverScript                     7/1/14-12/31/16
                       -------------------------------------------------
                        Ventegra                         1/1/15-12/31/16
                       -------------------------------------------------
                        WellCare                         1/1/15-12/31/16
------------------------------------------------------------------------

                     AstraZeneca Pharmaceuticals LP

                           1800 Concord Pike

                             P.O. Box 15437

                        Wilmington DE 19850-5437

                            Tel 302-886-3000

                         www.astrazeneca-us.com

March 7, 2019

The Honorable Charles E. Grassley
Chairman
Committee on Finance
U.S. Senate
Washington, DC 20510

The Honorable Ron Wyden
Ranking Member
Committee on Finance
U.S. Senate
Washington, DC 20510

Dear Chairman Grassley and Ranking Member Wyden:

    AstraZeneca's CEO Pascal Soriot appeared before your Committee on 
February 26, 2019 and answered a question from Senator Cortez Masto 
regarding whether AstraZeneca offers authorized generic versions of any 
of its products. At that time, Mr. Soriot indicated that AstraZeneca 
does not offer any authorized generics, however, following the hearing, 
Mr. Soriot was informed by AstraZeneca staff that an authorized generic 
is currently available in the U.S. This letter is intended to correct 
the record regarding that inadvertent oversight.

    AstraZeneca does, in fact, currently have one authorized generic in 
the U.S. market, and it was launched more than 3 years after the first 
generic of that product was introduced. Authorized generics are not a 
primary area of focus for AstraZeneca and are introduced on a selective 
basis. In limited circumstances, AstraZeneca has made an authorized 
generic available through a third-party distributor. Because patient 
prescription access and coverage may vary with respect to branded 
versus generic medicines, AstraZeneca believes it is important to keep 
branded options available for patients who continue to rely on them.

    We appreciate your invitation to discuss important issues of 
patient access and affordability with the Committee and the opportunity 
to supplement Mr. Soriot's testimony. We look forward to working with 
you as a constructive partner in addressing challenges in our health-
care system.

Sincerely,

Christie Bloomquist
Vice President, Corporate Affairs, North America

                                 ______
                                 
   Prepared Statement of Jennifer Taubert, Executive Vice President, 
     Worldwide Chairman, Janssen Pharmaceuticals, Johnson & Johnson
    Chairman Grassley, Ranking Member Wyden, and members of the 
committee, thank you for the opportunity to be here to discuss how we 
can ensure that Americans have affordable access to the best healthcare 
today and to the extraordinary medical breakthroughs of tomorrow.

    I am Jennifer Taubert, and I lead the Janssen Pharmaceutical 
Companies of Johnson & Johnson. At Janssen, we focus on discovering and 
developing transformational medicines that treat and cure some of the 
world's most challenging diseases, including blood cancers like 
multiple myeloma, chronic lymphocytic leukemia, and mantle cell 
lymphoma; prostate cancer; HIV; schizophrenia and other serious mental 
illnesses; cardiovascular diseases; rheumatoid arthritis; Crohn's 
Disease and other destructive gastrointestinal illnesses; and pulmonary 
hypertension, among others.

    Like many of you, I know what it's like when a loved one faces a 
serious disease. My own mother died of lung cancer in 1988, in her 40s. 
At the time, there was very little that could be done for my mom. I've 
committed my career to bringing families genuine, meaningful hope--hope 
for years of life, hope for the chance to be there for a daughter's 
wedding or the birth of a grandchild.
                        commitment to innovation
    Last year Janssen invested $8.4 billion globally in research and 
development,\1\ making Janssen one of the world's top research and 
development (``R&D'') investors in any industry, anywhere in the 
world.\2\ In fact, our investment in R&D last year was 86 percent more 
than we spent on sales and marketing. This substantial investment has 
enabled us to research and develop more than 100 medicine candidates 
last year; and, over the past 5 years, we have introduced six 
innovative products in the U.S.\3\ The nine Breakthrough Therapy 
Designations we have received from the Food and Drug Administration 
(``FDA'') reflect the significance of the advances we are pursuing in 
areas of profound unmet medical need.\4\
---------------------------------------------------------------------------
    \1\ Johnson & Johnson, FY18-Q4 Form 10-K for the Period Ending 
December 31, 2018 (filed February 20, 2019).
    \2\ PricewaterHouseCoopers. ``2018 Global Innovation 1000 Study.'' 
https://www.strategyand.
pwc.com/innovation1000.
    \3\ U.S. Food and Drug Administration Center for Drug Evaluation 
and Research. ``NDA and BLA Approval Reports--New Molecular Entity 
(NME) Drug and New Biologic Approvals.'' https://wayback.archive-
it.org/7993/20170404174205/https://www.fda.gov/Drugs/Develop
mentApprovalProcess/HowDrugsareDevelopedandApproved/
DrugandBiologicApprovalReports/NDAandBLAApprovalReports/ucm373420.htm.
    \4\ U.S. Food and Drug Administration Center for Drug Evaluation 
and Research. ``CDER Breakthrough Therapy Designation Approvals.'' 
https://www.fda.gov/downloads/Drugs/DevelopmentApprovalProcess/
HowDrugsareDevelopedandApproved/DrugandBiologicApproval
Reports/NDAandBLAApprovalReports/UCM481542.pdf.

    Our investment changes lives. It has helped turn HIV from a death 
sentence into a manageable disease. Today, people with HIV can have a 
near-normal life expectancy.\5\ And we are working on a vaccine with 
the potential to eliminate HIV altogether. Our biologic therapies have 
transformed the lives of patients with Inflammatory Bowel Disease by 
dramatically improving their quality of life. Our therapies have 
reduced major bowel surgeries for patients with Crohn's Disease by 82 
percent and cut hospitalizations by 65 percent.\6\ In ulcerative 
colitis patients, our therapies have reduced the need for total 
colectomy by 41 percent.\7\ One of our earliest pharmaceutical 
innovations enabled people with serious mental illness to be treated at 
home and in their communities rather than in psychiatric institutions, 
and today our innovative first and only 4-time-a-year schizophrenia 
treatment is improving adherence and breaking the cycle of 
hospitalization so that people with schizophrenia can live their best 
lives.\8\ In the area of mental health, we are also investigating a new 
medicine for people suffering from treatment-resistant depression, 
which profoundly impacts these patients and their families and loved 
ones as well. Our first-in-class cancer medicines have helped patients 
with some of the most common and deadly types of cancer live longer, in 
some cases for many additional years.\9\, \10\ In multiple 
myeloma, one of our medicines has more than doubled the length of time 
patients live without return of their disease.\11\ We recently launched 
a new prostate cancer treatment that delays the spread of the disease 
by over an additional two years versus the prior standard of 
care.\12\, \13\
---------------------------------------------------------------------------
    \5\ Trickey, Adam, Margaret T. May, Jorg-Janne Vehreschild, Niels 
Obel, M. John Gill, Heidi M. Crane, Christoph Boesecke et al. 
``Survival of HIV-positive patients starting antiretroviral therapy 
between 1996 and 2013: a collaborative analysis of cohort studies.'' 
The Lancet HIV 4, no. 8 (2017): e349-e356. doi: 10.1016/S2352-
3018(17)30066-8.
    \6\ Lichtenstein, Gary R., Songkai Yan, Mohan Bala, Marion Blank, 
and Bruce E. Sands. ``Infliximab maintenance treatment reduces 
hospitalizations, surgeries, and procedures in fistulizing Crohn's 
disease.'' Gastroenterology 128, no. 4 (2005): 862-869. doi: 10.1053/
j.gastro.2005.01.048.
    \7\ Sandborn, William J., Paul Rutgeerts, Brian G. Feagan, Walter 
Reinisch, Allan Olson, Jewel Johanns, Jiandong Lu et al. ``Colectomy 
rate comparison after treatment of ulcerative colitis with placebo or 
infliximab.'' Gastroenterology 137, no. 4 (2009): 1250-1260. 
doi:10.1053/j.gastro.2009.06.061.
    \8\ INVEGA TRINZA U.S. Prescribing Information, January 2019. 
http://www.janssenlabels.
com/package-insert/product-monograph/prescribing-information/
INVEGA+TRINZA-pi.pdf.
    \9\ IMBRUVICA U.S. Prescribing Information, January 2019. https://
www.imbruvica.com/docs/librariesprovider7/default-document-library/
prescribing-information.pdf.
    \10\ ZYTIGA U.S. Prescribing Information, April 2019. http://
www.janssenlabels.com/package-insert/product-monograph/prescribing-
information/ZYTIGA-pi.pdf.
    \11\ Bahlis, Nizar, Meletios A. Dimopoulos, Darrell J. White, Lotfi 
Benboubker, Gordon Cook, Merav Leiba, P. Joy Ho et al. ``Three-Year 
Follow-up of the Phase 3 Pollux Study of Daratumumab Plus Lenalidomide 
and Dexamethasone (D-Rd) Versus Lenalidomide and Dexamethasone (Rd) 
Alone in Relapsed or Refractory Multiple Myeloma (RRMM).'' (2018): 
1996-1996. doi: 10.1182/blood-2018-99-112697.
    \12\ DARZALEX U.S. Prescribing Information, June 2018. http://
www.janssenlabels.com/package-insert/product-monograph/prescribing-
information/DARZALEX-pi.pdf.
    \13\ ERLEADA U.S. Prescribing Information, February 2018. http://
www.janssenlabels.com/package-insert/product-monograph/prescribing-
information/ERLEADA-pi.pdf.

    This progress against some of the world's most challenging diseases 
is heartening but hard-won. Continued advancement will require 
perseverance and dedication. For example, we remain very committed to 
continuing research exploring new approaches and investigational 
medicines to prevent Alzheimer's dementia, which starts many years 
before the full onset of disease. In fact, we have invested billions of 
dollars in this area, and despite some significant projects that were 
halted because of lack of efficacy or a newly identified imbalance in 
benefit-risk, we continue to invest with the goal of conquering this 
---------------------------------------------------------------------------
major public health challenge in our lifetimes.

    Defeating Alzheimer's would not only change the lives of millions 
of patients and their families, it would dramatically change the 
economic burden of the disease. According to one analysis, if a new 
treatment that delays the onset of Alzheimer's by just five years were 
approved by 2025, the U.S. would save an estimated $367 billion each 
year by 2050.\14\
---------------------------------------------------------------------------
    \14\ Alzheimer's Association. ``Changing the Trajectory of 
Alzheimer's Disease: How a Treatment by 2025 Saves Lives and Dollars.'' 
May 2015. https://www.alz.org/media/Documents/changing-the-trajectory-
r.pdf.

    In fact, across a wide range of conditions, prescription medicines 
play a key role in keeping people well and productive and preventing 
the need for costly procedures and hospitalizations. For example, since 
the introduction of antiretroviral therapies, we've seen up to a 
$402,000 lifetime cost savings for each HIV patient diagnosed at an 
early stage.\15\ Cardiovascular medicines have led to a 27 percent 
reduction in costs for hospitalizations and procedures.\16\ In fact, 
the U.S. health-care system could save $213 billion annually with the 
correct use of prescription medications.\17\, \18\
---------------------------------------------------------------------------
    \15\ Farnham, Paul G., Chaitra Gopalappa, Stephanie L. Sansom, 
Angela B. Hutchinson, John T. Brooks, Paul J. Weidle, Vincent C. 
Marconi, and David Rimland. ``Updates of Lifetime Costs of Care and 
Quality-of-Life Estimates for HIV-Infected Persons in the United 
States: Late Versus Early Diagnosis and Entry Into Care.'' Journal of 
Acquired Immune Deficiency Syndromes 64, no. 2 (2013): 183-189. doi: 
10.1097/QAI.0b013e3182973966.
    \16\ Gotto, Antonio M., Stephen J. Boccuzzi, John R. Cook, Charles 
M. Alexander, James B. Roehm, Gregg S. Meyer, Michael Clearfield, 
Stephen Weis, and Edwin Whitney. ``Effect of Lovastatin on 
Cardiovascular Resource Utilization and Costs in The Air Force/Texas 
Coronary Atherosclerosis Prevention Study (AFCAPS/TexCAPS).'' The 
American Journal of Cardiology 86, no. 11 (2000): 1176-181. 
doi:10.1016/s0002-9149(00)01198-x.
    \17\ IMS Institute for Healthcare Informatics, ``Avoidable Costs in 
U.S. Healthcare'' (June 2013). http://offers.premierinc.com/rs/381-NBB-
525/images/Avoidable_Costs_in%20_US_Healthcare-
IHII_AvoidableCosts_2013%5B1%5D.pdf.
    \18\ Roebuck, M.C., J.N. Liberman, M. Gemmill-Toyama, and T.A. 
Brennan. ``Medication Adherence Leads to Lower Health Care Use and 
Costs Despite Increased Drug Spending.'' Health Affairs 30, no. 1 
(2011): 91-99. doi:10.1377/hlthaff.2009.1087.

    But medicines can't make a difference if patients who need them 
can't get them. We understand concerns about the cost of health care. 
Although prescription medicines represent only 14 percent of overall 
health-care spend--a figure that has remained relatively steady for the 
past decade and is projected to remain so into the future \19\--and 90 
percent of prescriptions are filled with generics,\20\ managing the 
cost of medicines, particularly what patients pay at the pharmacy 
counter, is important.
---------------------------------------------------------------------------
    \19\ Altarum Institute. ``A 10-Year Projection of the Prescription 
Drug Share of National Health Expenditures, Including Nonretail.'' 
Report. August 2015. http://altarum.org/sites/default/files/uploaded-
publication-files/Non-Retail%20Rx%20Forecast%20Data%20Brief%2010-14-14.
pdf.
    \20\ IQVIA. ``2017 Medicine Use and Spending in the U.S. a Review 
of 2017 and Outlook to 2022.'' April 2018. https://www.iqvia.com/-/
media/iqvia/pdfs/institute-reports/medicine-use-and-spending-in-the-us-
a-review-of-2017-and-outlook-to-2022.pdf.
---------------------------------------------------------------------------
                        our approach to pricing
    At Janssen, we take a responsible approach to pricing that 
recognizes our dual responsibility to patients today and patients 
tomorrow. Patients today need access to our medicines. Patients 
tomorrow count on us to deliver cures and treatments for the most 
challenging, intractable diseases. When we set an initial price for our 
medicines, we balance:

          Value to patients, the health-care system, and society. We 
        consider how the medicine will improve patient health and 
        assess its potential to reduce other costs--surgeries, hospital 
        stays, or long-term care, for example--and the improvement the 
        medicine represents over the existing standard of care.

          Affordable access to medicines for people who need them. We 
        want to ensure appropriate insurance coverage so that patients 
        who are prescribed our medicines can get them.

          Ability to develop future groundbreaking cures and 
        treatments. We have an obligation to ensure we have the 
        resources necessary to invest in future R&D to address serious 
        unmet medical needs.

    The list price of a medicine is a starting point that is ultimately 
reduced by the substantial discounts, rebates, and fees we provide to 
insurance companies, pharmacy benefit managers (``PBMs''), government 
programs, and others. We pay required discounts to government programs, 
and we negotiate with private payers so that they will cover our 
medicines and make them available to patients with lower out-of-pocket 
cost. In 2018, we provided approximately $21 billion in discounts and 
rebates on our medicines--an overall reduction from list price of 47 
percent. For some of our medicines, and for some of our customers, we 
pay discounts, rebates, and fees totaling well over 50 percent of our 
list price--so middlemen in the supply chain in those cases realize a 
majority of the revenue.

    All told, while our 2018 aggregate list price increase was 6.3 
percent,\21\ for the second year in a row discounts and rebates 
outweighed that increase, and aggregate net price--in other words, the 
real price--decreased by 6.8 percent.\22\
---------------------------------------------------------------------------
    \21\ Represents the year-over-year change in the average list 
price, or wholesale acquisition cost (``WAC'').
    \22\ Represents the year-over-year change in the average net price, 
which is WAC less rebates, discounts, and returns.

                   trends in pharmaceutical spending
    The fact is that across the industry net prices for branded 
medicines have increased well below the rate of medical inflation in 
recent years.\23\, \24\, \25\, \26\ In 
2017, the total expenditure on pharmaceuticals in the U.S. grew by only 
0.4 percent, compared to a 3.9 percent increase in overall health 
spending and a 4.6 percent increase in hospital spending.\27\
---------------------------------------------------------------------------
    \23\ IQVIA INSTITUTE for Human Data Science. ``The Global Use of 
Medicine in 2019 and Outlook to 2023.'' Report. January 2019. https://
www.iqvia.com/-/media/iqvia/pdfs/institute-reports/the-global-use-of-
medicine-in-2019-and-outlook-to-2023.pdf.
    \24\ U.S. Department of Labor. Bureau of Labor Statistics. 
``Consumer Price Index--December 2016.'' News release, January 18, 
2017. https://www.bls.gov/news.release/archives/cpi_01182017.pdf.
    \25\ U.S. Department of Labor. Bureau of Labor Statistics. 
``Consumer Price Index--December 2017.'' News release, January 12, 
2018. https://www.bls.gov/news.release/archives/cpi_01122018.pdf.
    \26\ U.S. Department of Labor. Bureau of Labor Statistics. 
``Consumer Price Index--December 2018.'' News release, January 11, 
2019. https://www.bls.gov/news.release/pdf/cpi.pdf.
    \27\ U.S. Centers for Medicare and Medicaid Services. ``NHE Fact 
Sheet.'' December 6, 2017. https://www.cms.gov/research-statistics-
data-and-systems/statistics-trends-and-reports/national
healthexpenddata/nhe-fact-sheet.html.

    Unfortunately, these trends are not reflected in many patients' 
experiences at the doctor's office or pharmacy counter. In fact, total 
patient out-of-pocket spending on medicines grew by 54 percent from 
2006 to 2016.\28\
---------------------------------------------------------------------------
    \28\ Claxton, Gary, Larry Levitt, Matthew Rae, and Bradley Sawyer. 
``Increases in Cost-sharing Payments Continue to Outpace Wage Growth.'' 
Peterson-Kaiser Health System Tracker. June 15, 2018. https://
www.healthsystemtracker.org/brief/increases-in-cost-sharing-payments-
have-far-outpaced-wage-growth/.

    One reason patient out-of-pocket spending has grown is due to 
changes in how health insurance is designed and, specifically, how 
pharmaceutical benefits are managed. As one recent analysis shows, 
patients are required to pay 13 percent of overall pharmaceutical costs 
versus only 3 percent of hospital costs--even though medicine can help 
keep patients out of the hospital.\29\
---------------------------------------------------------------------------
    \29\ PhRMA. ``PhRMA Chart Packs: Biopharmaceuticals in 
Perspective.'' Report. 2018. https://www.phrma.org/report/chart-pack-
biopharmaceuticals-in-perspective-summer-2018.

    The reality is that our health coverage system simply wasn't built 
in anticipation of medicines that treat diseases previously only 
treated with surgeries, hospitalizations and other complex 
interventions. Medicines today can extend and transform life for people 
facing very challenging, often relatively rare, diseases. It's critical 
that we work together to ensure that today's medicines are more 
accessible and affordable for patients while at the same time 
preserving the incredible ecosystem of medical innovation that has 
delivered so much and promises so much more.
              solutions to address the challenges we face
    Above all, we need an American solution to this American challenge. 
We must maintain the hallmarks that make American health care 
remarkable: access to innovative therapies, personal choice, and 
doctors and patients making decisions based on what is right for each 
individual.

    At Janssen, we are committed to being part of the solution.

    We believe open dialogue and partnership is essential to addressing 
the challenges in our health-care system. That's why in 2016 we began 
issuing an annual Janssen U.S. Transparency Report, sharing information 
about how we invest our resources, price our medicines, and help people 
who need Janssen medicines get access to them. Just recently, we 
expanded our commitment to transparency, announcing plans to 
voluntarily include list price and potential patient out-of-pocket 
costs in our pharmaceutical direct-to-consumer TV advertising, starting 
with our most frequently prescribed medicine.

    These more recent steps build on a legacy of commitment to 
transparency at Janssen. For example, we believe that making clinical 
trial data available promotes the understanding of disease, expands the 
knowledge needed to develop new treatments, and generates new insights 
and more complete evidence that lead to better health-care decisions 
for patients. In a first-of-its-kind agreement with the Yale University 
School of Medicine, we share clinical trial data through the Yale Open 
Data Access (YODA) Project. Since 2014, YODA Project has served as an 
independent review panel, evaluating researchers' requests for access 
to participant-level trial data and research reports, which provide 
extensive details about the methods and results of a clinical trial. 
Researchers can use these clinical trial data in their own research to 
increase medical knowledge and improve public health.

    In the same spirit of open dialogue and partnership, we have 
consistently brought forward ideas and perspectives to both Congress 
and the administration, with the goal of building on what is working in 
our healthcare system while fixing what is not:
                        part d out-of-pocket cap
    While Medicare Part D is working for many seniors and has been 
effective in containing costs, we believe an out-of-pocket cap in 
Medicare Part D is a needed protection. Without a cap, Medicare 
beneficiaries face unlimited out-of-pocket expenses, and, as research 
shows, high out-of-pocket costs reduce patient adherence to prescribed 
treatments and make them more likely to abandon their prescriptions. 
Poor patient outcomes related to lack of adherence or abandonment of 
prescribed treatments can lead to an increase in overall health-care 
costs.

    Individual and group health insurance policies are already required 
to have out-of-pocket caps. We believe that Medicare, which serves some 
of the sickest and most vulnerable patients and is essential to the 
health of American seniors, should also have that protection. We have 
been working on policy approaches that would make it possible to 
implement an out-of-pocket cap in a fiscally responsible way without 
creating new costs or access barriers for patients. As Congress 
considers any changes to Part D, we look forward to discussing these 
ideas in more depth.
                         medicare part b reform
    We believe policy solutions in Medicare Part B should meet three 
objectives: (1) reduce cost and spending; (2) increase competition; and 
(3) remove incentives to prescribe higher cost therapies without 
causing significant disruption to physicians or patient care.

    As changes to Part B are contemplated, it is important to remember 
that Medicare currently benefits from aggressive negotiations in the 
commercial market through the Average Sales Price (ASP) mechanism. Any 
reform should therefore leverage the benefits of the existing system.

    In our response to the Health and Human Services advance notice of 
proposed rulemaking regarding Part B, we proposed an option that would 
allow Medicare to continue to achieve the negotiated cost savings of 
the free market, reduce Part B acquisition cost under the ASP-based 
model, and reimburse all stakeholders on a fee-based mechanism aligned 
with the services that they provide. Our proposal aims to eliminate 
incentives for selecting higher list price drugs while maintaining 
current Part B patient access to appropriate clinical care.
                             rebate reform
    We support reforms to the rebate system that restructure incentives 
to ensure patients benefit from a competitive marketplace and see lower 
out-of-pocket costs. In 2017, the pharmaceutical industry paid $150 
billion in negotiated rebates and discounts.\30\ As we have noted, too 
often these rebates and discounts are not shared with patients, leaving 
the sickest patients paying higher out-of-pocket costs. We anticipate 
eliminating rebates could result in lower list prices, provided these 
rebates and discounts are not replaced with equally high fees or other 
payments demanded by middlemen. We also strongly advocate that 
beneficiary copays be based on net price.
---------------------------------------------------------------------------
    \30\ Adam J. Fein. ``The Gross-to-Net Bubble Topped $150 Billion in 
2017.'' Drug Channels (April 24, 2018) (citing IQVIA Institute for 
Human Data Science. ``Medicines Use and Spending in the U.S.: A Review 
of 2017 and Outlook to 2022.'' Report. April 2018. https://
www.iqvia.com/institute/reports/medicine-use-and-spending-in-the-us-
review-of-2017-outlook-to-2022.

    Altering the current rebate structure would be a major change to 
the entire pharmaceutical supply chain. It would need to be done 
thoughtfully and carefully to avoid disruption for patients. We look 
forward to commenting on the administration's proposed rule in this 
area.
                            value-based care
    Our current system rewards the quantity or volume of care 
delivered, regardless of the results of that care. Consequently, 
sometimes we spend money on treatments, diagnostic procedures, and 
surgeries that provide limited value or may not even be needed, driving 
up health-care costs without actually improving patient health.

    At Janssen, we're working with partners throughout the health-care 
system to encourage more results-based health-care approaches. While we 
have negotiated several value-based contracts, current policy often 
limits our ability to implement creative solutions. To address policy 
barriers, we support the following measures:

          Establish safe harbors in the Federal Anti-Kickback Statute 
        that better enable manufacturers to partner with payors and 
        share risk; and,

          Clarify Medicaid pricing treatment, including existing 
        Medicaid best price requirements that inhibit companies from 
        offering arrangements that may yield lower price in some 
        circumstances.
             promoting competition on a level playing field
    Biosimilars--near copies of biologic medicines--have the potential 
to increase competition and bring down costs, which is why Janssen has 
long supported a 
patient-focused, science-based regulatory framework for biosimilars.

    Some stakeholders have called for government to drive uptake by 
creating further incentives for biosimilars. But policies designed to 
increase share for biosimilar manufacturers would distort the 
competitive environment and risk limiting the savings biosimilars 
deliver to patients and taxpayers. We saw this risk realized most 
recently in the 340B Drug Discount Program, where policy designed to 
encourage the use of biosimilars had the unfortunate effect of 
increasing cost to patients, including low-income patients who can 
least afford it, and to taxpayers.\31\
---------------------------------------------------------------------------
    \31\ Center for Biosimilars. ``340B Changes: What Biosimilar 
Manufacturers Need to Know.'' Feb. 19, 2018. https://
www.centerforbiosimilars.com/contributor/amanda-forys/2018/02/340b-
changes-what-biosimilar-manufacturers-need-to-know.

    When it comes to making more biosimilars available for patients and 
their physicians, competition, not government intervention, is the best 
approach. And that approach is working. Not only is competition driving 
prices down for both innovator biologics and biosimilars, the 
biosimilars pipeline is strong. Competition on a level playing field 
will keep it that way.
                              340b policy
    At Janssen, we recognize that the 340B Drug Discount Program plays 
an important role in the healthcare system, helping to ensure that low-
income, needy patients have appropriate access to medicine. However, 
congressional oversight, proper implementation, and equitable 
application of the program are essential to ensuring the 340B program 
is helping those it was designed to help.

    Under the 340B Drug Discount Program, we are required to provide 
significant discounts on certain medicines purchased by 340B covered 
entities (comprised of specific categories of hospitals, clinics, and 
health centers that meet Federal eligibility requirements). Growth in 
the 340B program has been well documented, and Janssen has experienced 
significant growth in this highly discounted channel as well. Although 
the program was intended to benefit needy patients, the facilities 
themselves receive the discounts. There is no requirement that 340B 
covered hospitals pass along those discounts to patients. 340B covered 
hospitals can therefore access 340B pricing on outpatient drugs for all 
of their patients, including wealthy and well-insured patients.

    A more direct and accountable link between the provision of the 
discount and patient access is needed. We believe the benefits of the 
program should flow more directly and transparently to needy patients. 
We support efforts to strengthen the 340B program through greater 
transparency and increased clarity and accountability for all 
stakeholders. These goals can be achieved through the establishment of 
clear, reasonable and auditable rules including a clear definition of 
``patient'' as well as hospital eligibility criteria.
                               conclusion
    We are here today at a moment of incredible hope, on the verge of 
extraordinary progress that could change our lives and the lives of our 
children and grandchildren. We have the opportunity to get this right 
for Americans today and for future generations. At Janssen, we are 
committed to bringing that promise to life with transformational 
medical innovation.

                                 ______
                                 
         Questions Submitted for the Record to Jennifer Taubert
               Questions Submitted by Hon. Chuck Grassley
     spending on advertising/marketing vs. research and development
    Question. The Department of Health and Human Services' proposed 
rule, ``Fraud and Abuse; Removal of Safe Harbor Protection for Rebates 
Involving Prescription Pharmaceuticals and Creation of New Safe Harbor 
Protection for Certain Point-of-Sale Reductions in Price on 
Prescription Pharmaceuticals and Certain Pharmacy Benefit Manager 
Service Fees,'' envisions that drug manufacturers will offer up-front 
discounts rather than the back-end rebates that are now commonly 
provided. Some observers argue that a 1996 court case called into 
question whether manufacturers could offer up-front discounts, 
resulting in today's rebate-based system. I've heard differing opinions 
as to whether the issues related to the initial court case are still 
relevant. If the HHS proposed rule is finalized, can you assure the 
committee that your company will offer up-front discounts? If not, why?

    Please describe how you expect your company to respond to the HHS 
proposed rule to eliminate safe harbor protection for back-end rebates 
in Medicare Part D that is referenced above if it is finalized. 
Assuming you are confident that antitrust laws do not prevent your 
company from offering up-front discounts, specifically, do you envision 
that your company lowers the list price of a drug to the current after-
rebate net price, offer discounts equal to the current rebate amount, 
or a combination of both?

    Answer. The 1996 antitrust law case cited, in our assessment, 
should not limit the ability to move from rebates to other types of 
discounts. Depending on whether elimination of rebates applies to the 
entire market or only to those related to Federal health plans and 
assuming rebates are not replaced by high fees or other costs that 
offset the amount saved, we expect to lower list prices or offer 
discounts for pass-through at the point of sale. In either case, we 
would need to renegotiate our agreements with customers.

    The degree to which we can convert current rebates to list price 
reductions or point-of-sale discounts will depend upon the details of 
the final regulation and the reactions of other stakeholders in the 
supply chain. We are concerned that PBMs may seek to replace rebate 
revenue with new and increasing fees or may seek to shift costs among 
supply chain participants through service fees.

    Question. To what extent are the back-end rebates your company 
currently offers contingent on the amount of market share realized for 
your drugs as a result of Part D plan formulary placement and other 
techniques?

    Answer. Janssen does not currently offer rebates contingent on the 
amount of market share for our drugs as a result of Medicare Part D 
formulary placement. In other words, Janssen's current Medicare Part D 
rebate agreements do not contain any market share performance 
requirement.

    Question. Please provide a breakdown of percentage of sales that go 
to each payer (including Medicare, Medicaid, private pay, other) and a 
similar percentage by volume of the total number of each drug compared 
to total volume. Please provide this data for the most recent year 
available.

    Answer. Potentially responsive information may not be maintained by 
the company in the ordinary course of business. As such, an answer to 
this question is not readily available.

    Question. Do your companies hire consultants or lobbyists to 
promote products at State Medicaid Pharmacy and Therapeutics 
Committees? To whom do you disclose advocacy activities surrounding 
State Medicaid programs, if at all?

    Answer. Janssen does not hire external lobbyists or consultants for 
the purpose of promoting products at State Medicaid Pharmacy and 
Therapeutics Committees. We have internal employees who register as 
lobbyists and provide information about Janssen products to State 
Medicaid Pharmacy and Therapeutics Committee personnel. We comply with 
varied State laws regarding advocacy, including disclosure 
requirements.

    Question. Please describe how the costs of patient assistance 
programs are accounted for within your company's financial statements. 
Please also describe the types of market information, such as 
prescribing and use patterns, that your company collects from different 
types of patient assistance programs and patient hub services.

    Answer. Our patient assistance programs include both commercial 
copay support programs and charitable donations, which include both 
financial contributions and pharmaceutical products.

    With respect to Janssen's copay card programs, the value of patient 
copayment support is recorded as a reduction in sales revenue. The 
administrative costs associated with implementing the copayment 
programs are captured in selling, marketing and administrative expenses 
on Johnson & Johnson's SEC Form 10K.

    With respect to the company's charitable free product programs, 
Janssen donates prescription products to the Johnson & Johnson Patient 
Assistance Foundation, Inc. (``JJPAF''), a 501(c)(3) organization with 
an independent board and decision-making. Janssen also makes financial 
contributions to JJPAF and other independent 501(c)(3) organizations. 
These product and financial donations are recorded as charitable 
deductions.

    With respect to our commercial patient assistance programs, we 
collect information that is needed to support administering the 
program, helping patients get access to the medically appropriate 
treatment they have selected, and identifying and addressing barriers 
to patient access.

    Question. Please provide a list of all contributions since January 
1, 2014, that your company has made to any tax-exempt organizations 
working on issues related to drugs within your product lines, including 
but not limited to patient groups, disease awareness groups, medical or 
professional societies, universities or hospitals, industry 
associations or leagues. For each contribution, please provide the name 
of the organization that received the donation, the date the donation 
was made, the amount of the donation, and a description of the purpose 
of the contribution (i.e., was the contribution for the general fund, a 
specific purpose to a specific program, or continuing medical 
education). Please also note whether the contribution was unrestricted 
or restricted; if it was restricted, please explain all restrictions. 
Finally, if your company maintains a foundation or other separate 
charitable arm, please provide the name of all such entities, and list 
all donations made from that entity or entities.

    Answer. Through our Janssen charitable giving, we're proud to make 
a difference for patients and for the communities where we live and 
work. Janssen provides charitable donations through an established 
application review and approval process designed to ensure that the 
recipient of any contribution (i) is a valid 501(c)(3) charitable 
organization; (ii) has an established, good reputation; and (iii) is 
not on a Federal exclusion list (if the non-profit is a provider or 
government contractor). In addition, the charitable contributions 
review process is designed to review requests for donations to make 
sure that they are not made for the purpose of inducing the use or 
recommending the use of any J&J product.

    Janssen releases a contributions transparency report 
(``Contributions Report'') that details all of the charitable donations 
from the company for the prior year. Please see the attached link for 
the most recently posted Contributions Report, https://www.janssen.com/
us/transparency/educational-charitable-contribution-disclosures.

    With respect to the Contributions Report, please note:

          In keeping with our donor agreements and applicable 
        regulatory guidance, financial donations made to independent 
        charitable foundations that assist patients who are 
        underinsured and in need of financial assistance with 
        treatment-related expenses are disclosed in aggregate on the 
        Janssen Contributions Report.

          Charitable contributions made by recently acquired company 
        Actelion are not included in our report. In future years, these 
        donations will be included in the Contributions Report.

          Donations in the amount of $270,000 have been made annually 
        to support the mission of PhRMA Foundation. These donations 
        were made on April 29, 2014; January 21, 2015; December 21, 
        2015; September 11, 2017; June 1, 2018; and January 15, 2019.

    Contribution Reports for years 2014 through 2017 are attached.

    Most donation requests seek support for a specific program or 
initiative. If approved, the use of the contributed funds will be 
restricted to the purpose set forth in the application request. The 
Contribution Report details this purpose in the project title section.

    In addition, the company's standard donation agreement used for 
most contributions stipulates that funds should not be used to (i) 
educate, train or support meals, salary, travel, consulting fees or any 
other reimbursement to U.S.-licensed physicians; or (ii) fund services 
for which the organization receives government reimbursement under a 
fee-for-service model.

    Janssen makes financial contributions and prescription product 
donations to the Johnson & Johnson Patient Assistance Foundation, Inc. 
(``JJPAF''), a 501(c)(3) organization with an independent board and 
decision-making. The JJPAF provides free products directly to patients 
who meet certain income requirements and who do not have insurance 
coverage. In limited circumstances, JJPAF may work with other non-
profit entities to distribute products to patients in need. JJPAF does 
not advise Janssen of the specific recipients of its donations.

    In 2018, Janssen donated approximately $1 billion in free product 
and financial support to the JJPAF, enabling it to provide medicines at 
no cost to approximately 76,000 patients.

    The Johnson & Johnson Foundation (``JJF'') is a private non-profit 
501(c)(3) organization, founded in 1953. Solely funded by the Johnson & 
Johnson Family of Companies, the Foundation is responsible for managing 
the Corporation's Global Community Impact (``GCI'') programs and 
activities across the globe. Donations made by this foundation are 
available publicly through the IRS Form 990 it submits each year.

    Question. Pay-for-delay agreements cost consumers and taxpayers 
billions in higher drug costs every year. The FTC has gone after drug 
companies that enter into these settlements where the brand pays the 
generic company to keep its lower cost alternative off the market. I'm 
the lead Republican sponsor of S. 64, the Preserve Access to Affordable 
Generics and Biosimilars Act, which would help put an end to these 
deals.

    Do you agree that these pay-off agreements keep drug costs high for 
patients because they delay competition?

    Has your company ever entered into these kinds of settlements with 
a generic company?

    Do you support the pay for delay bill?

    Answer. J&J has not entered into patent settlement agreements that 
require payment of money to a generic manufacturer. Since J&J has not 
entered into agreements of this type, we do not have direct experience 
with their competitive impacts. The current legal framework--FTC 
oversight and judicial review on a case-by-case basis--is intended to 
identify any patent settlement that is anti-competitive. It is 
important to note that not all settlement agreements would result in a 
delay in competition; for example, some agreements of this type might 
facilitate generic entry prior to patent expiry.

    Although we believe that the current legal framework is sufficient 
to ensure that patent settlements are not anti-competitive, we would 
not oppose pay-for-delay legislation, provided that such legislation 
clearly, and in a manner consistent with current case law, defines the 
specific features of settlement agreements within its scope, does not 
hinder the ability of parties to utilize settlement agreements to 
efficiently settle patent disputes, and allows for an assessment of the 
competitive impacts of individual settlement agreements on a case-by-
case basis.
                           rebate traps/walls
    Question. I'm increasingly concerned about the effect of so-called 
``rebate traps'' or ``rebate walls'' on patients' access to quality, 
lower cost medicine. I understand there is ongoing litigation 
challenging these practices as anti-competitive.

    Does your company engage in the bundling of rebates over multiple 
products? If so, why? And what benefit does the consumer gain from 
that?

    Answer. Like other companies with broad portfolios of medicines 
that are highly valued by payers, health-care providers, and patients, 
Janssen offers incremental value when customers make a broader range of 
our medicines available to patients. Similar programs are common in the 
pharmaceutical and other industries. These programs provide an 
incentive for the customer to utilize our products and can lower costs. 
Those savings may be passed through to patients.

    Question. Does your company view these practices as anticompetitive 
or harmful to patients' access to quality, lower cost medicine?

    Answer. Janssen's contract offerings encourage price competition 
among drug manufacturers and ultimately enhance patients' access to 
quality medicines at lower prices.

    Question. If a policy were adopted to eliminate rebates, or to 
require that rebate savings be passed on to the consumer, would that in 
and of itself solve the issue of rebate ``traps'' and ``walls''? And 
would consumers benefit from such a policy?

    Answer. We support reforms to the rebate system that restructure 
incentives to ensure patients benefit from a competitive marketplace 
and see lower out-of-pocket costs.

    It is important to note that in today's health-care marketplace, 
payers use their ability to influence utilization to extract rebates, 
thereby enhancing competition and lowering overall system costs. 
Unfortunately, these savings are not usually shared with patients.

    Similarly, if rebates are eliminated, we anticipate that payers 
will use their ability to influence utilization to extract discounts 
and fees from manufacturers.
                              drug pricing
    Question. When setting the list price of a drug, does your company 
consider regulatory costs or compliance? If so, how specifically do 
those factors affect the list price of a drug? Please provide at least 
one specific example, if applicable, from your current product 
portfolio.

    When setting the list price of a drug, does your company consider 
the risk of liability or litigation? If so, how specifically do those 
factors affect the list price of a drug? Please provide at least one 
specific example, if applicable, from your current product portfolio.

    Answer. At Janssen, we take a responsible approach to pricing that 
recognizes our dual responsibility to patients today and patients 
tomorrow. Patients today need access to our medicines. Patients 
tomorrow count on us to deliver cures and treatments for the most 
challenging, intractable diseases. When we set an initial list price 
for our medicines, we balance:

          Value to patients, the health-care system, and society.
              We consider how the medicine will improve 
        patient health. We also assess the medicine's potential to 
        reduce other costs--surgeries, hospital stays, or long-term 
        care, for example--and the improvement the medicine represents 
        over the existing standard of care.

          The importance of maintaining affordable access to medicines 
        for people who need them.
              We work with insurers, pharmacy benefits 
        managers, governments, hospitals, physicians, and other 
        providers of care so that patients who are prescribed our 
        medicines can get access to them.

          The importance of preserving our ability to develop future 
        groundbreaking cures and treatments.
              We have an obligation to ensure that the sale 
        of our medicines provides us with the resources to invest in 
        R&D to address serious, unmet medical needs.

    In addition, the sale of our medicines must enable us to cover the 
costs of compliance with all laws and regulations.

    Regarding the requests for specific examples from our current 
product portfolio, the information requested is confidential and 
competitively sensitive. As such, potentially responsive information is 
not available for public disclosure.

                                 ______
                                 
                Questions Submitted by Hon. Pat Roberts
    Question. What role do you see value-based arrangements (VBAs) 
playing in the effort to reduce prescription drug costs? What potential 
do these arrangements have to find the ``sweet spot'' between 
controlling costs to patients and encouraging innovation of new drugs?

    Answer. We believe a value-based health-care system has tremendous 
potential to improve patient health, increase access to care, and curb 
the growth in health-care spending. Our current health-care system 
rewards the quantity or volume of care delivered, regardless of the 
results of that care. Consequently, sometimes money is spent on 
treatments, diagnostic procedures, and interventions that provide 
limited value or may not even be needed, driving up healthcare costs 
without actually improving patient health.

    Shifting to a value-based system requires innovation in the way 
contracts between payers and manufacturers are structured. By creating 
common incentives to deliver value for patients, value-based 
agreements, including innovative approaches to contracting models, can 
provide better outcomes at lower costs. We have established several 
innovative, value-based contracts and continue to explore new 
opportunities. For example, we have contracts tied to measurable 
medical outcomes and contracts tied to offsets of other expenditures.

    Fundamentally we believe a value-based health system will drive 
down the amount of waste in our current health-care system, so the 
money spent actually makes a measurable difference in individual health 
and the health of our society overall. Efforts to achieve a more value-
based system have encouraged all stakeholders to more clearly define 
and measure the value of health-care services offered, including 
medicines. In a health-care system that rewards value over volume, we 
believe incentives will be greater to bring to market new drugs that 
can reduce the need for other costly health-care intervention and 
ultimately produce better health outcomes and lower cost.

    Question. How can VBAs help lower what patients pay out-of-pocket?

    Answer. Innovative contracting models can align the incentives of 
all stakeholders, including pharmaceutical companies, health-care 
providers, and payers, to achieve better outcomes for patients at a 
lower overall cost of care to the health-care system, including Federal 
programs. In most cases, because the pharmaceutical company agrees to 
share some of the risk around the economics of the arrangement for a 
particular medicine, the health plan or PBM will provide better access 
to that medicine, which may entail placing the medicine on a lower 
formulary tier. Lower formulary tier placement results in lower out-of-
pocket costs for patients. We know that rising patient copayments are a 
barrier to adherence and therefore to optimal outcomes. We believe that 
keeping out-of-pocket costs reasonable for patients is an important 
element of getting to better outcomes, and innovative contracts can 
support this goal.

    According to an analysis by PhRMA and Avalere Health, commercially 
insured patients in health plans with outcome-based contracts for 
diabetes, high cholesterol and HIV medicines between 2015 and 2017 had 
copays that were, on average, 28 percent lower for those medicines 
compared to patients in other plans.

    Question. Can Congress do more to allow for and encourage the use 
of VBAs?

    Answer. We are enthusiastic about the potential for expanding the 
use of innovative value-based agreements. Nevertheless, a number of 
technological and policy barriers can make these agreements challenging 
to implement. To address technological barriers, we advocate for 
modernizing our healthcare data system to make it easier to track 
patient outcomes. To address policy barriers, we support the following 
approaches: establishing safe harbors to better enable manufacturers to 
partner with payers and share risk; clarifying the treatment of value-
based contracts in government price calculations, including in the 
complex Medicaid Best Price determination; and making comparative 
formulary and cost-sharing information readily available so patients 
have the information they need to make better decisions.

                                 ______
                                 
                Questions Submitted by Hon. John Cornyn
    Question. We continue to hear that rebates negotiated off of the 
list price of a drug are both good and bad.

    Pharmacy benefit managers and plans have argued that rebates are 
used to lower premiums across the board and that it is the best way to 
seek a price concession on otherwise expensive drugs.

    Your industry argues that these payers are insisting on higher 
rebates that can only be achieved by raising list prices. But patients 
often lose under this system, with out of pocket costs being tied to 
list price. Insulin patients appear to be routinely impacted by this 
perversity in the system.

    Please explain to the committee how your company would reduce list 
prices if rebates were no longer a part of the equation?

    What assurance can you provide that you would in fact lower your 
prices?

    What actions should be taken to ensure that patients are actually 
seeing the benefits of lower out of pocket costs?

    Answer. Depending on whether elimination of rebates applies to the 
entire market or only to those related to Federal health plans and 
assuming rebates are not replaced by high fees or other costs that 
offset the amount saved, we expect to lower list prices or offer 
discounts for pass-through at the point of sale. In either case, we 
would need to renegotiate our agreements with customers.

    The degree to which we can convert current rebates to list price 
reductions or point-of-sale discounts will depend upon the details of 
the final regulation and the reactions of other stakeholders in the 
supply chain. We are concerned that PBMs may seek to replace rebate 
revenue with new and increasing fees or may seek to shift costs among 
supply chain participants through service fees.

    We support reforms to the rebate system that restructure incentives 
to ensure patients benefit from rebates and discounts that are 
provided.

    Question. If rebates are driving high list prices for drugs as drug 
manufacturers' claim, why do you think that Part B drugs, which have no 
PBM rebates, are also seeing significant price increases? Whose fault 
is that?

    Answer. Part B benefits from competitive commercial rebates and 
discounts, while maintaining access to medicines for our nation's 
seniors, through the Average Selling Price (``ASP''). ASP, which is the 
basis for Part B drug reimbursement, reflects all commercial discounts 
and rebates. Since both provider reimbursement and patient out-of-
pocket costs for Part B drugs are based on ASP, changes in a product's 
ASP is a more relevant indicator of true cost to the Medicare system 
and beneficiaries.

                                 ______
                                 
               Question Submitted by Hon. Michael B. Enzi
    Question. The Food and Drug Administration's drug review process is 
known to many as the ``gold standard'' for evaluating medical products. 
I've long thought that it is critical that we maintain public 
confidence in their ability to ensure that drugs are safe and 
effective. There is a perception among some, however, that biosimilars 
might not be as safe as their reference products. That perception can 
undermine patient and provider confidence. Do you believe that when FDA 
approves a biosimilar, providers can be confident that it is safe and 
effective?

    Answer. Biosimilars granted licensure by the FDA are by definition 
safe and effective and are highly similar to the reference biologic. We 
support the FDA's application of rigorous scientific standards and 
appropriate data requirements for the licensure of both biosimilars and 
interchangeable biosimilars, and we believe evidence and experience 
will drive patient and provider confidence in these products.

                                 ______
                                 
                 Questions Submitted by Hon. Todd Young
         re-evaluating business strategies in foreign countries
    Question. Since taking office, President Trump has made reducing 
drug prices one of his highest priorities--and has repeatedly spoken 
about his frustration with the U.S. subsidizing the costs of 
pharmaceuticals for the rest of the world. He has gone so far as to 
issue proposals, like the International Pricing Index (IPI) Model, in 
an attempt to bring down prescription drug prices.

    With the increased scrutiny of the industry and of the drug supply 
chain as a whole in the United States, have any of your companies re-
evaluated your business strategy in foreign countries?

    If not, then why?

    If a proposal, like IPI, were implemented, would it force your 
companies to potentially ``walk away from the negotiating table when 
other countries demand low prices subsidized by America's seniors,'' as 
HHS Senior Advisor for Drug Pricing Reform John O'Brien has said?

    What are some of your ideas on how we can ensure Americans aren't 
shouldering the full cost of pharmaceuticals?

    Answer. We continuously evaluate our global business strategy and 
country-
specific market access approaches in light of current conditions, 
including changing policies and circumstances.

    We support the use of trade tools to improve the policy environment 
for U.S. companies operating overseas and to enhance incentives for 
innovation. The U.S. government has already taken steps to advance this 
goal with some of our key trading partners. The U.S. Mexico Canada 
Agreement (``USMCA'') includes important provisions committing Canada 
and Mexico to recognize the value of pharmaceuticals either through the 
operation of competitive markets or through procedures that 
appropriately value pharmaceuticals. The agreement also contains 
procedural safeguards for U.S. companies. These include a requirement 
that Canada and Mexico provide opportunities for stakeholder comment on 
measures before they are finalized and also offer U.S. companies an 
opportunity to appeal administrative actions. These are critical tools 
that will help American companies obtain fair value for innovation 
outside the U.S.

    The U.S. government has announced its intention to negotiate trade 
agreements with Japan, the European Union, and the United Kingdom. 
These negotiations could address inadequacies in the systems of some 
our largest trading partners.

    The U.S. government can also effectively leverage existing trade 
agreements and tools like Organisation for Economic Cooperation 
accession negotiations to induce foreign governments to provide 
appropriate value for innovation and offer greater incentives for new 
treatments and cures.

              foreign countries' pricing and reimbursement

    Question. President Trump and Secretary Azar have both repeatedly 
described their frustrations with ``foreign freeloading'' of U.S. drugs 
in the last year.

    ``When foreign governments extort unreasonably low prices from U.S. 
drug makers, Americans have to pay more to subsidize the enormous cost 
of research and development. . . . It's unfair and it's ridiculous, and 
it's not going to happen any longer.''

    Do you agree that because of foreign countries' pricing and 
reimbursement systems, U.S. patients and innovators are shouldering the 
burden for financing medical advances?

    Answer. According to a report by the U.S. Department of Commerce, 
international reference pricing and controls suppress worldwide private 
research and development by up to 16 percent annually, leading to fewer 
new medicines launched each year. Conversely, recent estimates 
demonstrate that removing price controls in other wealthy countries 
would increase the number of available new treatments by 9 percent by 
2030, equivalent to a range of 8 to 13 new therapeutics that year.

    Question. How do foreign countries' pricing and reimbursement 
systems affect our prescription drug costs?

    Answer. While there is no direct relationship between U.S. drug 
prices and foreign prices, according to a report by the U.S. Department 
of Commerce, existing foreign price controls suppress worldwide private 
research and development and decrease the number of new treatments and 
cures, to the detriment of U.S. patients.

    It is important to note that most cross-country pricing comparisons 
focus solely on the list prices of medicines and do not account for the 
significant discounts required for participation in U.S. public 
programs, such as Medicaid, the 340B Drug Discount Program, and the 
Federal Supply Schedule (for U.S. Department of Veterans Affairs and 
the Department of Defense), as well as the discounts and rebates 
negotiated by private payers. For this reason, most international 
comparisons are not ``apples to apples.'' In addition, in other 
countries, medicine prices are achieved through national regulation, 
which often restricts or delays access to innovative medicines and 
limits patient and physician choice.

    Question. Are foreign governments taking note of the concerns being 
raised by the Trump administration and have they responded in any way?

    Answer. We understand that some foreign government officials have 
noted the concerns raised by the Trump administration and appear to be 
seeking a better understanding of the proposed policy changes in the 
United States and the potential future impacts on their countries.

    Question. Has there been any noticeable change in any of our trade 
agreements since these concerns have been raised by the Trump 
administration?

    Answer. The U.S.-Mexico-Canada Agreement (``USMCA'') contains 
important provisions on intellectual property that establish a higher 
global IP standard than in previous agreements, particularly with 
respect to data protection for biologics. The agreement also contains 
important provisions committing Canada and Mexico to recognize the 
value of pharmaceuticals either through the operation of competitive 
markets or through procedures that appropriately value pharmaceuticals. 
The agreement includes procedural safeguards for U.S. companies. These 
include a requirement that Canada and Mexico provide opportunities for 
stakeholder comment on measures before they are finalized and also 
offer U.S. companies an opportunity to appeal administrative actions. 
These are critical tools that will help American companies obtain fair 
value for innovation. The U.S. government has announced its intention 
to negotiate trade agreements with Japan, the European Union, and the 
United Kingdom. These negotiations could address inadequacies in the 
systems of some our largest trading partners. The U.S. government can 
also effectively leverage existing trade agreements and tools like 
Organisation for Economic Co-operation accession negotiations to induce 
foreign governments to provide appropriate value for innovation and 
offer greater incentives for new treatments and cures.
                  medicaid closed formulary proposals
    Question. In an attempt to bring down drug costs, various states 
have been exploring whether to exclude certain drugs from its Medicaid 
program. For example, the state of Massachusetts' recently asked CMS 
for permission to create a closed formulary where the state Medicaid 
program would pick at least one drug per therapeutic class. CMS denied 
their waiver request citing violation of federal law, but this proposal 
does bring up important questions on how to contain drug prices in 
state Medicaid programs.

    If the principles of the Medicare Part D program--including the 
necessary patient protections--were applied to State Medicaid programs, 
do you think it would lower drug costs while ensuring access to 
patients?

    Answer. By legislative design, the Medicaid Program already 
receives the ``best'' price, in addition to substantial rebates 
associated with an inflation penalty and negotiated supplemental 
rebates. The rebate is never less than 23.1 percent, the required 
statutory minimum, and often requires manufacturers to sell their 
products (both older and newer) for as low as 1 cent per pill or unit.

    The Medicaid drug rebate statute represents a carefully crafted 
legislative approach developed by Congress and designed as a package to 
offer Medicaid beneficiaries comprehensive coverage and access to 
outpatient drugs at the lowest cost in the marketplace. We support the 
significant access protections required under the current Medicaid Drug 
Rebate Program that serve a uniquely vulnerable population. We also 
question whether reducing access to medically necessary medication for 
vulnerable Medicaid beneficiaries will yield true program savings. Any 
further restrictions in medication access is likely to increase the 
risk of higher costs elsewhere in the health-care continuum. Moreover, 
vulnerable Medicaid beneficiaries may be particularly challenged to 
navigate the administrative, technical, logistical and other challenges 
that inevitably arise when additional restrictions are placed on their 
access to care.
                        medicaid ``best price''
    Question. In the Trump administration's Blueprint, they suggested 
that because drug manufactures have to give Medicaid the ``best price'' 
on drugs, there is no incentive to offer deeper discounts to other 
payers--both government and commercial--than what is already offered 
under the Medicaid Drug Rebate Program.

    Does the Medicaid ``best price'' requirement encourage 
manufacturers to increase initial prices?

    Answer. We take into account the Medicaid ``best price'' 
requirement at all stages of the drug lifecycle, including launch. We 
consider best price when offering large discounts to commercial 
customers after a drug is launched and when designing value-based 
agreements.

    Question. What, if any, changes would you suggest we make to the 
program?

    Answer. We are supportive of ongoing efforts to promote a value-
driven health-care system, including in Medicaid, and applaud recent 
efforts by both the administration and Congress that seek to address 
regulatory and legal uncertainty around value-based payment 
arrangements. We also support CMS's recent approvals of State proposals 
to advance specific Medicaid value-based arrangements with drug makers.
                        outcomes-based contracts
    Question. In almost all of your testimonies, you highlight your 
support of outcomes-based contracts and how we need to be shifting our 
system toward that approach.

    How will these contracts lower drug costs for patients in both the 
near term and long-term?

    How will they lower overall health-care costs for our Federal 
programs?

    What have the preliminary results looked like so far?

    Answer. Innovative contracting models can align the incentives of 
all stakeholders, including pharmaceutical companies, health-care 
providers, and payers, to achieve better outcomes for patients at a 
lower overall cost of care to the health-care system, including Federal 
programs.

    In most cases, because the pharmaceutical company agrees to share 
some of the risk around the economics of the arrangement for a 
particular medicine, the health plan or PBM will provide better access 
to that medicine, which often entails placing the medicine on a more 
preferable formulary tier. More preferable formulary tier placement 
results in lower out-of-pocket costs for patients. We know that rising 
patient copayments are a barrier to adherence and therefore to optimal 
outcomes. We believe that keeping out-of-pocket costs reasonable for 
patients is an important element of getting to better outcomes, and 
innovative contracts can support this goal.

    According to an analysis by PhRMA and Avalere Health, commercially 
insured patients in health plans with outcome-based contracts for 
diabetes, high cholesterol and HIV medicines between 2015 and 2017 had 
copays that were, on average, 28 percent lower for those medicines 
compared to patients in other plans.

    Innovative contracting models are still relatively new, and we look 
forward to the point at which we will have the long-term data necessary 
to evaluate the success of these programs with respect to health-care 
cost reduction. We are enthusiastic about the potential of innovative 
value-based contracting models to enable us to take full advantage of 
medicines' benefits, including their potential to reduce other health-
care costs.
                       transparency/point of sale
    Question. In almost all of your testimonies, you express your 
support for the Trump administration's proposal to allow manufacturers 
to provide PBMs up-front discounts that are passed onto patients at the 
point of sale.

    Do you feel like this proposal will make the transactions within 
the drug supply chain more transparent?

    If so, would this transparency bring down drug costs--overall and 
for specialty drugs?

    Answer. We do believe that a point-of-sale discount model, wherein 
manufacturer discounts could be passed through to a patient at the 
point-of-sale, will make price reductions offered by the manufacturer 
more transparent because these discounts would be more directly 
reflected in patient out-of-pocket cost at the pharmacy. However, we do 
not believe that the proposal will improve transparency with respect to 
fees or mark-ups to the price of drugs added elsewhere in the supply 
chain.

    Depending on whether elimination of rebates applies to the entire 
market or only with respect to Federal health plans and assuming 
rebates are not replaced by high fees or other costs that offset the 
amount saved, we expect to lower list prices or offer discounts for 
pass-through at the point of sale.
         the relationship between wholesalers and manufacturers
    Question. When talking about the pharmaceutical supply chain, a lot 
of focus has been placed on the pharmacy benefit manager. But there's 
another side of the equation that I'd like to ask about: how do 
wholesalers negotiate pricing with manufacturers?

    Answer. Janssen sells to wholesalers and specialty distributors at 
list price, with discounts customarily offered for prompt payment. 
Janssen occasionally offers discounts to wholesalers for discrete 
periods of time on certain products. These are generally offered to 
contracted, authorized wholesalers market-wide. In addition, Janssen 
negotiates service agreements with wholesalers and specialty 
distributors for bona fide services relating to distribution of Janssen 
products.

    Question. What impact does this have on drug costs?

    Answer. We do not know the details of the wholesalers' arrangements 
with downstream stakeholders such as pharmacies, hospitals, providers, 
and other sites of care.

    Question. What incentives or disincentives do they have to contain 
price increases?

    Answer. We are not in a position to comment on wholesaler 
incentives or disincentives to contain price increases.

                                 ______
                                 
                 Questions Submitted by Hon. Ron Wyden
                          proposed rebate rule
    Question. As has been done in many other settings, drug 
manufacturers said during the hearing that one reason list prices for 
drugs are high is that pharmaceutical benefit managers (PBMs) demand 
larger and larger rebates in order for the drug to receive favorable 
placement on a formulary. You and your colleagues who testified during 
the hearing stated if the administration's proposal on changes to the 
anti-kickback safe harbor for pharmaceutical rebates took effect, your 
company would likely lower list price.

    Like many Oregonians, I am skeptical drug manufacturers would 
voluntarily lower their prices. Therefore, would you support 
legislation that would (1) make similar changes the administration has 
put forward related to Part D and Medicaid managed care, (2) change the 
rebate system in a similar way to the proposal for the commercial 
market, and (3) require drug makers to lower the list price of their 
drugs equal to the amount of rebates provided today?

    Answer. We support reforms to the rebate system that restructure 
incentives to ensure patients benefit from a competitive marketplace 
and see lower out-of-pocket costs.

    Depending on whether elimination of rebates applies to the entire 
market or only to those related to Federal health plans and assuming 
rebates are not replaced by high fees or other costs that offset the 
amount saved, we expect to lower list prices or offer discounts for 
pass-through at the point of sale. In either case, we would need to 
renegotiate our agreements with customers.

    The degree to which we can convert current rebates to list price 
reductions or point-of-sale discounts will depend upon the details of 
the final regulation and the reactions of other stakeholders in the 
supply chain. We are concerned that PBMs may seek to replace rebate 
revenue with new and increasing fees or may seek to shift costs among 
supply chain participants through service fees.
                      medicaid drug rebate program
    Question. The Medicaid Drug Rebate Program (MDRP) requires 
manufacturers to provide a basic rebate and an additional inflationary 
rebate for both brand and generic drugs. The inflationary rebate is an 
increasingly substantial part of total rebates due in large part to 
large increases in drug prices that exceed inflation. Under current 
law, this inflationary rebate is capped at 100 percent of Average 
Manufacturer Price (AMP). This is the case even when manufacturers 
continue to raise their prices well above inflation.

    Please provide a list of all of your pharmaceutical products that 
have reached the Medicaid AMP rebate cap in any of the 20 quarters from 
January 1, 2014 through December 31, 2018.

    For each drug listed in response to question 1, please also provide 
a list of which quarters and years each drug hit the cap.

    Answer. Janssen has numerous current products, and products that 
have since been sold to third parties, that have reached the Medicaid 
AMP rebate cap in at least one of the 20 quarters from 1Q 2014 through 
4Q 2018. The fact that these products reaching the 100 percent AMP cap 
is based on confidential metrics reported under the Medicaid Drug 
Rebate Program. The Medicaid AMP rebate cap is reached when AMP is less 
than or equal to the Unit Rebate Amount (URA). URA is calculated based 
on AMP and Best Price--which are confidential under the Medicaid Drug 
Rebate statute at 42 U.S.C. ' 1396r8(b)(3)(D). There are exceptions in 
the statute that permit the Secretary and State Medicaid agencies to 
disclose the information only in certain situations, including 
disclosure to CBO. Thus, if there was legislation proposing to amend 
the 100 percent AMP cap, CBO would be able to access the drugs and 
underlying data to estimate the cost/savings to the government of such 
a legislative change.

    The product-specific information requested is confidential and 
competitively sensitive. As such, potentially responsive information is 
not available for public disclosure.
                medicaid drug rebate program compliance
    Question. I am concerned about recent reports and legal settlements 
surrounding drug manufacturers' failure to comply fully with the 
requirements of the MDRP. For example, an analysis by the U.S. 
Department of Health and Human Services Office of Inspector General 
found that between 2012 and 2016 taxpayers may have overpaid by as much 
as $1.3 billion for 10 potentially misclassified drugs. That is why I 
introduced the Right Rebate Act with Chairman Grassley to prevent drug 
manufacturers from manipulating Medicaid to increase their profits. 
However, I continued to be concerned about oversight and manufacturer 
compliance with the requirements of the Medicaid Drug Rebate Program. 
Accordingly, please describe the following:

    Your company's current compliance plan and procedures used to 
ensure compliance with the requirements of the Medicaid Drug Rebate 
Program including internal audits or other checks you use to identify 
compliance vulnerabilities.

    Any past or ongoing issues of non-compliance.

    Any corrective actions taken to address identified problems or 
issues of non-
compliance with the MDRP and how such steps were communicated to the 
Centers for Medicare and Medicaid Services.

    Any steps taken to improve compliance and ensure that all Medicaid 
drug rebates owed to the Federal Government and the States are paid in 
full.

    Answer. We comply with the obligations we undertake when 
participating in U.S. Federal, State, or local government contracts and 
government pricing programs such as the Medicaid Drug Rebate Program. 
We have an established compliance framework along with organizational 
structure and accountabilities designed to assure compliance. Our 
framework includes testing and monitoring and an obligation to correct 
any identified discrepancies. As such, any discrepancies have been 
timely addressed and corrected.

    The other information requested is confidential. As such, 
potentially responsive information is not available for public 
disclosure.
                 bonus payments tied to specific drugs
    Question. I am concerned by the potential for employee financial 
incentives to encourage high launch prices and price increases for 
prescription drugs.

    Is your salary, bonus or other compensation tied to sales or 
revenue targets of a single product your company sells? Has it ever 
been? If yes, please state the product or products to which your 
salary, bonus or other compensation was tied.

    Answer. At no time during her employment with the Johnson & Johnson 
Family of Companies has Ms. Taubert's salary, bonus, or other 
compensation been tied to sales or revenue targets of a single product.

    Question. Is your salary, bonus, or other compensation tied to 
either revenue or net income of the company as a whole? Has it ever 
been? If yes, please explain what assumptions about price increases are 
used when the compensation committee sets revenue or net income goals. 
Does the compensation committee provide any guidance to executives in 
regards to the amount of revenue that the company will generate from 
price increases versus volume growth?

    Answer. We structure performance-based compensation to reward an 
appropriate balance of short-term and long-term financial and strategic 
business results, with an emphasis on managing the business for long-
term results. Our compensation program's emphasis on long-term value 
reduces the possibility that our executives make excessively risky 
business decisions that could maximize short-term results at the 
expense of long-term value.

    Ms. Taubert's base salary is tied to performance, market data, 
responsibilities, time in position, internal equity, and experience. 
Ms. Taubert's bonus and long-term incentive compensation has been and 
is awarded based on her individual performance and the company's 
performance.

    The compensation committee does not provide guidance to executives 
regarding the amount of revenue that the company will generate from 
price increases versus volume growth.
        provision of rebates in exchange for formulary placement
    Question. In today's system, drug makers receive a limited time 
window to sell their drug without competition. After that period has 
expired, low-cost generics should become available. However, drug 
makers often prevent access to these cheaper generic drugs in Medicare. 
Researchers have found that 72 percent of Medicare Part D plans charged 
lower cost-sharing for a brand name drug compared to its generic 
equivalent. This means seniors were charged less out of pocket for 
brand name drugs compared to generics that are on average four times 
cheaper than the brand-named drug. This happens because drug makers pay 
a rebate to the Part D plans in order to give the more expensive drug 
better treatment than a generic. As a result, Medicare spending 
increases due to the current structure of the Part D benefit.

    Has your company ever paid a rebate to a Part D plan so that a 
brand name drug would get preferential treatment (i.e., lower cost-
sharing or less utilization management) compared to a cheaper generic?

    If so, please provide: a list of the drugs for which your company 
has done this since January 1, 2014; and the number of Part D plans in 
which this type of rebate was given for each drug in each year.

    Answer. In negotiations with PBMs and payers, Janssen may offer 
multiple different rebate options. The PBM or payer has sole discretion 
over how formularies are structured. In some cases, a PBM or payer may 
establish a formulary that puts a branded drug in a preferential 
position.

    The information requested is confidential and competitively 
sensitive. As such, potentially responsive information is not available 
for public disclosure.
                               net prices
    Question. Your testimony stated that ``while our 2018 aggregate 
list price increase was 6.3 percent, for the second year in a row 
discounts and rebates outweighed that increase, and aggregate net 
price--in other words, the real price--decreased by 6.8 percent.'' 
According to your testimony, the net price ``represents the year-over-
year change in the average net price, which is WAC less rebates, 
discounts, and returns.'' Please describe how the company's year-over-
year aggregate net price is calculated. Please also specifically 
address the following questions:

    Answer. Average net price change represents the year-over-year 
change in the average net price, which is Wholesale Acquisition Cost 
less rebates, discounts, and returns.

    Question. How many products are included in the calculation of the 
average net price change? What was the median net price change?

    Answer. We believe weighted average net price change is the 
appropriate metric for evaluating list price changes across the 
portfolio. There are 99 products (brands) included in the average net 
price change calculation. The 2017-2018 weighted average net price 
change is -6.8 percent. The non-weighted average 2017-2018 net price 
change is -3.7 percent. The 2017-2018 median net price change is -1.9 
percent. It is important to note that non-weighted average or median 
net price change treats all medicines--whether used by many patients or 
by very few--equally, so those figures are not useful or valuable in 
understanding the actual change experienced.

    Question. Is net price weighted? If so, how? For example, in 
determining the aggregate net price does the company assign different 
weights to different products based on volume or other factors? Are 
``on patent'' and ``off patent'' drugs weighted identically? Are other 
statistical weights used or are all products treated equally?

    Answer. Annual net price change versus prior year is calculated at 
the product level and weighted across the company's U.S. product 
portfolio using net trade sales. All products, both ``on patent'' and 
``off patent,'' are included.

    Question. Does the figure that you provided during your testimony 
account for U.S. prices, international prices, or both? Generally 
speaking, when your company reports net price changes, does it 
differentiate between U.S. and international prices?

    Answer. The figure provided, -6.8 percent, accounts for 2018 net 
price change for our U.S. pharmaceutical business only. We disclose 
this figure in our annual Janssen U.S. Transparency Report.

    Question. Please list the five drugs your company sold in the U.S. 
that had the greatest year-over-year net price increase in 2018, noting 
the increase for each drug by dollar figure and percentage. Please list 
the five drugs your company sold in the U.S. that had the lowest year-
over-year net price increase (and/or the greatest decrease) in 2018, 
noting the increase (or decrease) for each drug by dollar figure and 
percentage.

    Answer. The information requested is confidential and competitively 
sensitive. As such, potentially responsive information is not available 
for public disclosure.

    Question. For 2018, what was the average net price change in the 
U.S. market for (1) drugs with no competition, (2) drugs with only 
branded competition, and (3) drugs with generic competition?

    Answer. The information requested is confidential and competitively 
sensitive. As such, potentially responsive information is not available 
for public disclosure.

    Question. Your company noted in its annual financial filing with 
the Securities and Exchange Commission that ``Immunology was negatively 
impacted by lower sales of REMICADE' (infliximab) due to 
increased discounts/rebates and biosimilar competition,'' and ``Strong 
sales of long-acting injectables INVEGA TRINZA'/
TREVICTA' (paliperidone palmitate) and INVEGA 
SUSTENNA'/XEPLION' were partially offset by 
cannibalization of RISPERDAL CONSTA' (risperidone) and 
generic competition for CONCERTA'/methylphenidate,'' and 
``Lower sales of INVOKANA'/INVOKAMET' 
(canagliflozin) in the U.S. was primarily due to an increase in price 
discounts, higher rebates and market share decline driven by 
competitive pressure. Lower sales of XARELTO' (rivaroxaban) 
were driven by an increase in discounts and rebates, partially offset 
by an increase in market share.'' What were the year-over-year net 
price changes for each of these drugs?

    Answer. The information requested is confidential and competitively 
sensitive. As such, potentially responsive information is not available 
for public disclosure.

    Question. Please define the following terms that were used on page 
20 of your company's annual report for the year ending December 31, 
2018 regarding sales of various pharmaceutical products: strong uptake, 
market growth, and share gain. Please also define ``reduction in 
sales,'' as used in the sentence ``Biosimilar versions of 
REMICADE' have been introduced in certain markets outside 
the U.S., resulting in a reduction in sales of REMICADE' in 
those markets.''

    Answer. ``Strong uptake'' means that we are seeing significant 
utilization of a medicine that was recently introduced into the market 
or approved for a new indication.

    ``Market growth'' refers to increase in utilization of medicines 
overall for a particular disease state or in a particular class of 
medicines.

    ``Share gain'' means that within a class of medicines or 
therapeutic area, a particular medicine is being selected and utilized 
more than it had been previously and now represents a greater 
percentage of utilization within that class relative to competitor 
medicines.

    ``Reduction in sales'' in the sentence you reference means that 
revenues for REMICADE' are lower than they have been in 
previous years. Please note that our 2018 Annual Report goes on to 
state, ``In the U.S., a biosimilar version of REMICADE' was 
introduced in 2016, and additional competitors continue to enter the 
market. Continued infliximab biosimilar competition in the U.S. market 
will result in a further reduction in U.S. sales of 
REMICADE'.''

                                 ______
                                 
              Questions Submitted by Hon. Robert Menendez
    Question. During the hearing, when I asked whether your company 
engaged in tactics to delay generic production of your products, you 
answered ``no.'' However, your Johnson & Johnson's Actelion appears on 
the FDA's list of companies who have access complaints against them. 
Can you explain the discrepancy between your answer and the FDA list? 
The FDA list can be found here: https://www.fda.gov/Drugs/
DevelopmentApprovalProcess/HowDrugsareDevelopedandApproved/
ApprovalApplications/AbbreviatedNewDrugApplicationANDAGenerics/
ucm607738.htm.

    Answer. Johnson & Johnson acquired Actelion in June 2017. We share 
FDA's commitment to policies that promote access to generics when 
balanced with the protection of innovation and the safeguarding of 
patient safety. It is important to note that the FDA's website on 
Reference Listed Drug (``RLD'') Access Inquiries does not differentiate 
between inquiries and complaints, and does not clarify whether the RLD 
Sponsor made samples available after the FDA issued a Safety 
Determination Letter. Following the receipt of a Safety Determination 
Letter from the FDA, Actelion has actively entered into a supply 
agreement with every generic manufacturer who has requested testing 
samples of our products. This is true for each instance cited in the 
FDA's RLD Access Inquiry list. Actelion is also actively engaging with 
generic manufacturers to develop shared REMS programs that protect 
patient safety while enabling patient access to our medicines.

    Question. When new products enter the market, do drug companies set 
high initial rebates and then provide deep rebates in order to gain 
access to insurance plan's formularies?

    Answer. At Janssen, we take a responsible approach to pricing that 
recognizes our dual responsibility to patients today and patients 
tomorrow. Patients today need access to our medicines. Patients 
tomorrow count on us to deliver cures and treatments for the most 
challenging, intractable diseases. When we set an initial list price 
for our medicines, we balance:

          Value to patients, the health-care system, and society.
              We consider how the medicine will improve 
        patient health. We also assess the medicine's potential to 
        reduce other costs--surgeries, hospital stays, or long-term 
        care, for example--and the improvement the medicine represents 
        over the existing standard of care.

          The importance of maintaining affordable access to medicines 
        for people who need them.
              We work with insurers, pharmacy benefits 
        managers, governments, hospitals, physicians, and other 
        providers of care so that patients who are prescribed our 
        medicines can get access to them.

          The importance of preserving our ability to develop future 
        groundbreaking cures and treatments.
              We have an obligation to ensure that the sale 
        of our medicines provides us with the resources to invest in 
        R&D to address serious, unmet medical needs.

    We go through a lengthy process to gather the information necessary 
to assess the medicine according to these factors. We use this 
information to determine the value of our medicine compared to what is, 
or will be, available to treat the same condition--be it other 
medicines, surgery, or other forms of health care.

    Question. If CMS finalizes the rebate rule, do you anticipate 
future products entering the market with significantly lower initial 
list prices?

    Answer. Depending on whether elimination of rebates applies to the 
entire market or only to those related to Federal health plans and 
assuming rebates are not replaced by high fees or other costs that 
offset the amount saved, we expect to lower list prices or offer 
discounts for pass-through at the point of sale. In either case, we 
would need to renegotiate our agreements with customers.

    The degree to which we can convert current rebates to list price 
reductions or point-of-sale discounts will depend upon the details of 
the final regulation and the reactions of other stakeholders in the 
supply chain. We are concerned that PBMs may seek to replace rebate 
revenue with new and increasing fees or may seek to shift costs among 
supply chain participants through service fees.

                                 ______
                                 
              Questions Submitted by Hon. Thomas R. Carper
    Question. What are your recommendations for lowering prices for the 
40 percent of drugs that do not offer rebates in Medicare Part D? In 
the health insurance plans that you offer your employees, do you ask 
your insurers to pass through the full manufacturer rebates to the 
beneficiaries?

    Answer. Drugs that offer lower rebates tend to be drugs that face 
less competition in the marketplace. Increased competition can lead to 
lower prices of branded and generic drugs. FDA Commissioner Scott 
Gottlieb prioritized faster approval of generic drugs. In 2018, FDA set 
a record by approving an estimated 971 generic drugs.

    Within today's health-care system, we do recover manufacturer 
rebates from our PBM. Any savings we receive are used to offset out-of-
pocket costs for employees and total plan costs. In order to help 
ensure affordability for our employees, we limit out-of-pocket pharmacy 
costs through a monthly per prescription cap.

    Question. The systems for pricing and distributing drugs are opaque 
and difficult to understand. What are your recommendations for 
increasing transparency in how your companies set the list prices for 
drugs, and for improving transparency in the supply chain for 
prescription drugs? Would you support federal standards for 
transparency in setting the list prices for drugs?

    Answer. At Janssen, we issue an annual U.S. Transparency Report 
that explains what we take into account in setting list prices for our 
medicines. When we set an initial list price for our medicines, we 
balance:

          Value to patients, the health-care system, and society.
              We consider how the medicine will improve 
        patient health. We also assess the medicine's potential to 
        reduce other costs-- surgeries, hospital stays, or long-term 
        care, for example--and the improvement the medicine represents 
        over the existing standard of care.

          The importance of maintaining affordable access to medicines 
        for people who need them.
              We work with insurers, pharmacy benefits 
        managers, governments, hospitals, physicians, and other 
        providers of care so that patients who are prescribed our 
        medicines can get access to them.

          The importance of preserving our ability to develop future 
        groundbreaking cures and treatments.
              We have an obligation to ensure that the sale 
        of our medicines provides us with the resources to invest in 
        R&D to address serious, unmet medical needs.

    The list price we set is a publicly available figure that can be--
and is-- compared to other options available. We believe that a point-
of-sale discount model will make price reductions offered by the 
manufacturer more transparent because these discounts will be directly 
reflected in patient out-ofpocket cost at the pharmacy. However, we do 
not believe that the proposal will improve transparency with respect to 
fees or mark-ups to the price of drugs added elsewhere in the supply 
chain.

    Transparency that is meaningful and valuable to patients can help 
achieve what we all want: better health care, at more manageable cost, 
and, most importantly, longer, healthier lives for all.

    We believe an environment that encourages medical innovation and 
robust competition to deliver the best health outcomes is essential to 
achieving these goals. Our support for legislation that establishes a 
federal standard for transparency in setting the list price for drugs 
would depend on the extent to which the proposed standards maintained 
such an environment.

    Question. In nearly every sector of the health-care industry, 
Medicare, Medicaid, employers, and insurers are moving away from fee-
for-service payments to reimbursements based on value and performance. 
Prescription drugs and medical devices were the glaring exceptions to 
this trend until recently. How many of your drugs are included in 
value-based contracts and how many patients are benefiting from them? 
How do these value-based contracts work to lower drug prices for both 
patients and taxpayers?

    Answer. We have established several innovative, value-based 
contracts with insurers and continue to explore new opportunities. For 
example, in immunology, we partnered with payers to create an agreement 
in which the price of a medicine for chronic immune conditions varies 
based on how well it works for patients. In oncology, we partnered with 
public and private payers on novel contracts for patients with prostate 
cancer and agreed in one contract to provide additional rebates to the 
insurer for plan members who meet eligibility criteria and whose 
treatment duration is shorter than a predetermined period of time. We 
also partnered with a leading payer on a contract under which we are 
paid more if data show our medicine that treats adults with type 2 
diabetes contributed to lowering other identified health-care costs, 
such as the use of additional medicines.

    Question. Last year, Senator Portman and I did an investigation on 
the pricing of an opioid overdose reversal drug called EVZIO, 
manufactured by Kaleo. Kaleo increased the price of EVZIO from $575 in 
2014 to $4,100 in 2017. We found that the best price Medicare was able 
to get for EVZIO, about $4,000, was much higher than the price other 
Federal programs and private insurers were able to get. It seemed that 
Kaleo was able to get this higher price of $4,000 from Medicare by 
helping doctors fill out paperwork showing that the drug was medically 
necessary, even though there are cheaper alternatives on the market. As 
a result of the investigation, Kaleo announced it will bring a generic 
version of the drug to market at only $168 per pack. Are any of your 
companies providing medical necessity paperwork to doctors in order to 
get your drugs covered by Medicare?

    Answer. Like other pharmaceutical companies, we offer a sample 
letter of medical necessity that offices can complete using their own 
clinical judgment regarding the medical and clinical rationale for 
submission to the insurance company or PBM. We also research and 
provide payer-specific forms required to provide medical necessity 
information such as payer-specific prior authorization forms.

    Question. In 2017, the Rand Corporation estimated that biosimilar 
drugs, which are competitors to complex, biologic drugs, could save the 
United States more than $50 billion over the next decade. Some of you 
have also argued that increasing the use of biosimilar drugs would help 
lower drugs costs for consumers and taxpayers. What is delaying the 
uptake of biosimilar drugs in the United States? What policies do you 
recommend to increase the development of biosimilar drugs?

    Answer. The goal of biosimilar policy should be to lower costs for 
the health-care system and patients, and not simply to encourage 
biosimilar uptake without regard to price. The current open and 
competitive environment supports price competition and biosimilar 
uptake as appropriate. For example, the net price of infliximab 
products, including the innovator product REMICADE', is 
falling. Furthermore, the uptake of infliximab biosimilars in the U.S. 
is consistent with branded biologic launches of immunology products, 
including those that provide a clinical benefit over the standard of 
care.

    Biologics are used in patients with serious, chronic conditions, 
many of whom have taken years to become stable on a branded product. 
Health-care providers and patients may naturally be hesitant to switch 
medicines in these circumstances. The approval of an interchangeable 
biosimilar may address some of the physician and patient reservations 
about switching a stable patient to a non-interchangeable biosimilar.

    The biosimilars pipeline is strong and a diverse group of 
companies--traditional pharmaceutical manufacturers as well as 
manufacturers focused on biosimilars--is investing in the space. For 
example, in the immunology therapeutic area alone, at least 18 
biosimilars are currently in clinical development or undergoing FDA 
review.

    We fully support a regulatory framework for FDA review and approval 
of biosimilars and interchangeable biosimilars with standards and 
policies that are science-based and rooted in patient safety. 
Ultimately, the uptake of biosimilars will be reliant on competitive 
pricing and on patient and prescriber confidence. Provider and patient 
confidence can be strengthened by the application of rigorous review 
standards, including the robust approach to interchangeability that FDA 
is pursuing and appropriate standards regarding biosimilar to 
biosimilar switching.

    Biosimilar manufacturers need access to samples of reference 
products to perform comparative testing required to demonstrate 
biosimilarity or interchangeability. We cooperate with manufacturers of 
generic drugs and biosimilars so they have access to samples of our 
medicines at reasonable, market-based prices. To facilitate access to 
product samples while fostering efficiencies in the delivery and 
oversight of healthcare, we believe that manufacturers should identify 
for FDA a point of contact to facilitate access to samples for each 
approved reference product. When a Risk Evaluation and Mitigation 
Strategy (REMS) is in place, the REMS should facilitate the safe use of 
medicine and ensure access for appropriate patients; it should not be 
used to hinder provision of product samples for use in developing a 
generic or biosimilar. We believe FDA should finalize draft guidance, 
issued December 2018, describing a process for FDA determination that 
protocols pertaining to biosimilarity and interchangeability testing 
contain safety protections comparable to an applicable REMS with 
limited distribution elements. A letter from FDA stating comparable 
protections exist and indicating FDA would not consider it to be a 
violation of the REMS to provide samples to the biosimilar manufacturer 
provides needed assurances for reference product manufacturers about 
both the safe use of our products and regulatory compliance.

    The Purple Book is an essential resource for many stakeholders and 
should be enhanced to provide timely information to stakeholders, to 
clarify practices regarding substitution, and to provide information to 
assure the appropriate use of biosimilars and interchangeable products. 
In addition, the Purple Book should include detailed information about 
approved biosimilars and interchangeable biosimilars, including, for 
example, a description or listing of pivotal clinical trials considered 
in FDA's approval of the biosimilar.

                                 ______
                                 
             Questions Submitted by Hon. Benjamin L. Cardin
    Question. The United States is one of the only countries in the 
world to allow prescription drug manufacturers to advertise directly to 
consumers through magazines, billboards, radio, and television 
commercials. While I will not argue that it is beneficial to educate 
consumers about an unfamiliar disease and encourage them to seek 
medical help, most commercials from all of your companies recommend 
asking about a specific brand name drug, not a medical condition. 
Furthermore, even if your advertisements follow all FDA rules and list 
medication side effects, they also almost always list these while a 
smiling, apparently healthy person is walking on a beach.

    Researchers say that this type of imagery, combined with viewing 
hours of drug commercials each month, leads consumers to underestimate 
the risks associated with medications. For the past decade, studies 
have shown that aggressive direct-to-consumer advertising is associated 
with rising drug prices and an increase in inappropriate drug 
prescriptions.

    Since researchers have concluded that consumers are 
misunderstanding the benefits and risks described in your ads, what 
further policies could help you and your colleagues ensure that you are 
educating patients in a clear manner?

    Answer. At Janssen, we believe patients can get and stay healthier 
when they are well informed about their conditions and treatment 
options. We provide accurate, up-to-date educational materials in 
language that is clear and understandable for consumers to help 
patients facing diseases our medicines treat and to help patients who 
take our medicines understand how to use them properly. Our product-
specific communications, including our DTC advertising, are designed to 
encourage appropriate dialogue between patients and healthcare 
providers about the risks and benefits of treatment.

    We believe acting ethically and responsibly is not only the right 
thing to do but also the right way to do business. We follow all 
relevant laws and regulations regarding the promotion of prescription 
drug products and submit promotional materials to the U.S. Food and 
Drug Administration at the time of initial publication or 
dissemination.

    We are always open to ways to improve our communication, including 
DTC, to ensure patients better understand the benefits and risks of our 
medicines.
           pharmaceutical companies continue to raise prices
    Question. As you are well aware, high prescription drug prices are 
the number one concern for Americans and their families. According to 
the Organisation for Economic Co-operation and Development, the average 
American spends around $1,208 annually on prescription drugs. There 
have been several instances where brand name or even generic drugs that 
have been on the market for years continue to increase in price.

    One of the most well-known examples is Mylan's increase of the 
price of EpiPen from less than $100 in 2007 to more than $600 in 2016. 
Another example, is the ever-increasing price of insulin. Sanofi 
increased the price of a vial of Lantus from $88.20 in 2007 to $307.20 
in 2017. And those are just a small sample of price increases.

    Why don't we see price decreases for drugs that have been on the 
market for years without new formulations or added benefit?

    Answer. In fact, net price does often decrease, sometimes quite 
significantly, for medicines that have been on the market for years 
because of competition from other, newer medicines for the same 
condition. Competition brings down price for payers such as PBMs and 
insurers, although unfortunately patients often do not benefit from the 
lower net price.

    It is also important to note that biopharmaceutical innovation 
paves the way for the introduction of generic medicines, which enables 
medicine costs to be reduced over time. In the U.S., medicines lose 
patent protection, on average, about 12 years after they are 
introduced. When that happens, prices generally drop significantly, 
giving patients ongoing access to effective therapies at a lower cost.
                             pay for delay
    Question. Pay for delay is a tactic that more and more branded drug 
manufacturers have been using to stifle competition from lower-cost 
generic manufacturers. This allows you to sidestep competition by 
offering patent settlements that pay generic companies not to bring 
lower-cost alternatives to market.

    These pay-for-delay patent settlements benefit both brand-name 
pharmaceutical companies by helping them avoid costly patent litigation 
and general manufacturers by rewarding them a hefty sum to delay 
entering the market with a cheaper drug alternative. However, these 
deals do not benefit consumers. According to an FTC study, these 
anticompetitive deals cost consumers and taxpayers $3.5 billion in 
higher drug costs every year.

    Does your company partake in pay-for-delay settlements?

    Answer. We have not entered into patent settlement agreements that 
require payment of money to a generic manufacturer.

    Question. Why would a pharmaceutical company enter into a pay-for 
delay agreement?

    Answer. We have not entered into patent settlement agreements that 
require payment of money to a generic manufacturer and, therefore, we 
cannot speculate as to why other companies might enter into such 
agreements in specific cases.

    Question. Do you think these agreements stifle competition and 
prevent generic alternatives to your branded medications?

    Answer. We have not entered into patent settlement agreements that 
require payment of money to a generic manufacturer, so we do not have 
direct experience with their competitive impacts. However, we believe 
that the competitive impact of any individual settlement agreement must 
be evaluated on a case-by-case basis. The current legal framework--FTC 
oversight and judicial review on a case-by-case basis--is intended to 
identify any patent settlement that is anti-competitive.
                            drug rebate rule
    Question. In January, the Department of Health and Human Services' 
(HHS) Office of Inspector General (OIG) promulgated a new regulation to 
remove regulatory safe harbor protections under the Anti-Kickback 
Statute (AKS) for rebates on prescription drugs rebates paid by 
manufactures to PBMs under Medicare Part D and for Medicaid managed 
care organizations (MCOs). The OIG proposal attempts to ban most 
rebates by eliminating their regulatory protections.

    The rule is predicted to increase net drug costs in its early 
years. The CMS actuaries estimate it would cost $196 billion over 10 
years. Despite this high price tag, the beneficiary benefits are 
limited. The proposed rule notes that under the CMS Actuary's analysis, 
the majority of beneficiaries would see an increase in their total out-
of-pocket payments and premium costs; reductions in total cost sharing 
will exceed total premium increases.

    I wanted to ask a question about the administration's rebate rule, 
which I understand that many of the drug manufacturers, and your main 
trade association, strongly support. According to an analysis of the 
rule by the Office of Actuaries at CMS, drug manufacturers are likely 
to initially retain 15 percent of the current rebates as higher net 
drug prices.

    Given that estimate, can you provide the committee with any 
assurances that prices will not increase under this proposed rule?

    Answer. Depending on whether elimination of rebates applies to the 
entire market or only to those related to Federal health plans and 
assuming rebates are not replaced by high fees or other costs that 
offset the amount saved, we expect to lower list prices or offer 
discounts for pass-through at the point of sale. In either case, we 
would need to renegotiate our agreements with customers.

    The degree to which we can convert current rebates to list price 
reductions or point-of-sale discounts will depend upon the details of 
the final regulation and the reactions of other stakeholders in the 
supply chain. We are concerned that PBMs may seek to replace rebate 
revenue with new and increasing fees or may seek to shift costs among 
supply chain participants through service fees.

                                 ______
                                 
               Questions Submitted by Hon. Sherrod Brown
    Question. As I understand it, 2 years ago PhRMA updated its 
membership standards to require member companies to meet two new 
criteria: (1) each company must meet a 3-year average global research 
and development to sales ratio of 10 percent or greater, and (2) each 
company must spend at least $200 million on R&D per year over a 3-year 
average. As a result of these changes, several companies who continue 
to operate under business models that prioritize price gouging over 
innovation, left PhRMA.

    Given your company's role in setting a higher standard for R&D, 
would you support a more even playing field by raising the minimum bar 
for R&D across the entire pharmaceutical sector, in particular for 
companies that participate in government programs such as Medicare and 
Medicaid?

    Answer. We are proud to set a high standard for R&D investment. In 
2018 Janssen invested $8.4 billion globally in research and 
development. This investment in R&D was 86 percent more than we spent 
on sales and marketing. However, we would not support a policy that 
requires a certain amount of R&D spending for a manufacturer's products 
to be covered by Medicare and Medicaid because we would not want to 
deny patients access to needed medication based on the investment 
decisions of these drug companies.

    Question. According to an article recently published in the Journal 
of the American Medical Association, medical marketers spend nearly $30 
billion dollars in 2016, up from $17 billion in 1997. Direct-to-
Consumer (DTC) advertising had the biggest percentage increase: from 
$2.1 billion, or 11.9% of all medical marketing, in 1997 to $9.6 
billion, or 32% of total spending, in 2016.

    Can you please provide what your ratio of spending on sales and 
marketing to research and development is today?

    Answer. In 2018, the pharmaceutical segment of Johnson & Johnson 
invested 86 percent more in R&D globally ($8.4B) than we spent on 
global sales and marketing ($4.5B).
                             price-gouging
    Question. Sanofi, as I understand it, has made a pledge to the 
public to limit its price increases to the national health expenditures 
growth projection.

    Would your company commit to a cap on annual price increases as 
part of your PhRMA membership criteria?

    Answer. In 1993, the Pharmaceutical Manufacturers Association (PMA, 
now the Pharmaceutical Research and Manufacturers of America or PhRMA) 
asked the Department of Justice (``DOJ'') Antitrust Division to review 
a proposal for a PMA effort to ask member companies to commit 
voluntarily to limiting price increases on their entire line of 
prescription medicines in any calendar year to an amount not to exceed 
the increase in the Consumer Price Index (CPI). In its response, the 
DOJ Antitrust Division stated that, ``[T]he Department believes that 
the proposed program would violate the antitrust laws. . . . The 
Supreme Court has. . . made clear that agreements that set maximum 
prices are as equally illegal as agreements that set minimum prices.'' 
The DOJ noted that it ``intends to bring suit to challenge the program 
if PMA and its members go forward with this proposal.'' Therefore, we 
are unable to commit to such a cap as part of PhRMA membership 
requirements due to likely enforcement action by the DOJ.

    Question. What policies would you propose to help ensure lower 
launch prices for new drugs?

    Answer. We support rebate reforms that ensure patients benefit from 
negotiated rebates and discounts--$150 billion in 2017 alone--and, as a 
result, have patients see lower out-of-pocket costs at the pharmacy.

    Depending on whether elimination of rebates applies to the entire 
market or only to those related to Federal health plans and assuming 
rebates are not replaced by high fees or other costs that offset the 
amount saved, we expect to lower list prices or offer discounts for 
pass-through at the point of sale. In either case, we would need to 
renegotiate our agreements with customers.

    The degree to which we can convert current rebates to list price 
reductions or point-of-sale discounts will depend upon the details of 
the final regulation and the reactions of other stakeholders in the 
supply chain. We are concerned that PBMs may seek to replace rebate 
revenue with new and increasing fees or may seek to shift costs among 
supply chain participants through service fees.
                              transparency
    Question. In many of your testimonies, you mentioned that the 
current system of pharmacy benefit manager (PBM) back-end rebates do 
not rarely results in a scenario where the PBM passes on savings to 
consumers at the point of sale (POS). The administration recently 
proposed a rule to eliminate the anti-kickback statute safe harbor 
protections for these drug rebates.

    Do you agree that greater transparency should be required to 
understand how manufacturers and PBMs are negotiating prices and 
rebates to ensure that savings are passed down to beneficiaries?

    Answer. We believe that a point-of-sale discount model will make 
price reductions offered by the manufacturer more transparent because 
these discounts will be directly reflected in patient out-of-pocket 
cost at the pharmacy. However, we do not believe that the proposal will 
improve transparency with respect to fees or mark-ups to the price of 
drugs added elsewhere in the supply chain.

    Depending on whether elimination of rebates applies to the entire 
market or only to those related to Federal health plans and assuming 
rebates are not replaced by high fees or other costs that offset the 
amount saved, we expect to lower list prices or offer discounts for 
pass-through at the point of sale.
                                  pbms
    Question. An Axios article from March 7, 2019 highlights the fact 
that, while ``pharmaceutical companies put a lot of the blame for high 
drug prices on pharmacy benefit managers,'' many large pharmaceutical 
companies ``rely on PBMs to manage their own health-care benefits.''

    In your role as an employer, does your company contract with a 
pharmaceutical benefit manager (PBM) to administer the prescription 
drug benefits for your employees and negotiate lower drug costs on your 
behalf?

    Answer. As an employer, we design our own pharmacy benefit program 
and contract with a PBM for administration and to negotiate on our 
behalf.

    Question. For those of you who do use a PBM to help manage the 
prescription drug benefit for your employees, how do you utilize the 
rebates your PBM negotiates to lower health-care costs or drug costs 
for your employee plans and what does your company do with that 
savings? Specifically, do the savings go toward lowing premiums?

    Answer. We use any savings to offset total plan costs, enhance 
benefits, and lower premium and out-of-pocket costs for our employees. 
In order to ensure our employees have affordable access to medicine, we 
have a monthly per prescription out-of-pocket cap.

    Question. For those of you who do use a PBM to help manage the 
prescription drug benefit for your employees, does your PBM offer 
point-of-sale rebates to your employees?

    Answer. We are exploring the possibility of offering point-of-sale 
rebates with our PBM.

                                 ______
                                 
             Questions Submitted by Hon. Sheldon Whitehouse
    Question. Please describe any policy changes you support that would 
result in your company lowering the list prices of its drugs.

    Answer. We support rebate reforms that ensure patients benefit from 
negotiated rebates and discounts-- $150 billion in 2017 alone--and, as 
a result, have patients see lower out-of-pocket costs at the pharmacy.

    Depending on whether elimination of rebates applies to the entire 
market or only to those related to Federal health plans and assuming 
rebates are not replaced by high fees or other costs that offset the 
amount saved, we expect to lower list prices or offer discounts for 
pass-through at the point of sale. In either case, we would need to 
renegotiate our agreements with customers.

    The degree to which we can convert current rebates to list price 
reductions or point-of-sale discounts will depend upon the details of 
the final regulation and the reactions of other stakeholders in the 
supply chain. We are concerned that PBMs may seek to replace rebate 
revenue with new and increasing fees or may seek to shift costs among 
supply chain participants through service fees.

    Question. How much does your company's research and development 
portfolio rely on taxpayer-funded research conducted by the National 
Institutes of Health (NIH)? How many of your company's products are 
based, at least in part, on NIH research, and how many are the result 
of research funded solely by your company?

    Answer. The NIH plays an important role in medical research, 
primarily funding basic research on medical problems. The 
pharmaceutical industry is responsible for developing the solutions--
undertaking the long, financially risky, and costly process to discover 
a compound and develop new medicines that meet the stringent safety and 
efficacy requirements of the FDA. In those instances where NIH 
contributes to a product that is brought to market, NIH would receive 
any contracted license fees or royalties.

    Question. In each of the last 5 years, how much has your company 
spent on research and development versus the advertising and marketing 
of your products?

    Answer. Below is a chart including global Janssen R&D and Sales and 
Marketing expenditures over the last 5 years. Sales and marketing 
includes expenses related to: (1) selling, (2) marketing management, 
(3) market and consumer research, and (4) advertising and promotion.

------------------------------------------------------------------------
                                   2014    2015    2016    2017    2018
------------------------------------------------------------------------
Janssen R&D                        $6.2B   $6.8B     $7B   $7.9B   $8.4B
------------------------------------------------------------------------
Janssen Sales and Marketing        $4.5B   $4.6B   $4.5B   $4.2B   $4.5B
------------------------------------------------------------------------

    Question. During the hearing, you mentioned that your company would 
be likely to lower the list prices of its drugs if the recent proposal 
by the Trump administration to change the current system of rebates was 
extended to the private market.

    If the policy was extended to the private market, how large would 
the list price reductions be relative to the size of the rebates your 
company is currently providing?

    How will this proposal affect how your company sets the list prices 
for new drug products?

    Answer. Depending on whether elimination of rebates applies to the 
entire market or only to those related to Federal health plans and 
assuming rebates are not replaced by high fees or other costs that 
offset the amount saved, we expect to lower list prices or offer 
discounts for pass-through at the point of sale. In either case, we 
would need to renegotiate our agreements with customers.

    The degree to which we can convert current rebates to list price 
reductions or point-ofsale discounts will depend upon the details of 
the final regulation and the reactions of other stakeholders in the 
supply chain. We are concerned that PBMs may seek to replace rebate 
revenue with new and increasing fees or may seek to shift costs among 
supply chain participants through service fees.

    Question. If the proposal is finalized and not extended to the 
private market, will your company make any list price reductions? If 
so, how large would the reductions be relative to the size of the 
rebates your company is currently providing?

    Answer. If elimination of rebates applies only to Medicare and 
Medicaid Managed Care and assuming rebates are not replaced by high 
fees or other costs that offset the amount saved, we expect to offer 
discounts for pass-through at the point of sale. To do so, we would 
need to renegotiate our agreements with customers.

    The degree to which we can convert current rebates to point-of-sale 
discounts will depend upon the details of the final regulation and the 
reactions of other stakeholders in the supply chain. We are concerned 
that PBMs may replace rebate revenue with new and increasing fees or 
may shift costs among supply chain participants through service fees.

                                 ______
                                 
                Question Submitted by Hon. Maggie Hassan
    Question. In June of 2018, the Medicaid and CHIP Payment and Access 
Commission (MACPAC) unanimously recommended under Recommendation 1.1 in 
their annual report to Congress that Congress remove the statutory 
requirement that manufacturers blend the average manufacturer price 
(AMP) of a brand drug and its authorized generic.\1\
---------------------------------------------------------------------------
    \1\ MACPAC, ``Improving Operations of the Medicaid Drug Rebate 
Program,'' https://www.macpac.gov/wp-content/uploads/2018/06/Improving-
Operations-of-the-Medicaid-Drug-Rebate-Program.pdf.

    This requirement created an unintended loophole. Rather than use 
the price of the authorized generic, drug companies can sell its 
authorized generic to a corporate subsidiary at an artificially lower 
price, and use that lower price to bring down the AMP, which in turn 
---------------------------------------------------------------------------
lowers the rebate obligation.

    Does your company engage in this practice? Has your company ever 
engaged in this practice in the past?

    Answer. We do not include authorized generic internal transfer 
prices to an affiliate when calculating Average Manufacturer Price for 
the branded product. Under previous versions of the statute and CMS 
guidance, we have at times in the past included in Average Manufacturer 
Price the transfer prices of our authorized generic sold to an 
affiliate.

                                 ______
                                 
           Questions Submitted by Hon. Catherine Cortez Masto
    Question. As a portion of your revenue, for what percentage of the 
drugs in your portfolio do you offer no rebates? Based on the drugs in 
your pipeline, do you foresee that portion growing? For those drugs is 
your list price equal to your net price?

    Answer. The information requested is confidential and competitively 
sensitive. As such, potentially responsive information is not available 
for public disclosure.

    Question. Do you invest more in R&D than you generate in US sales 
revenue? Please include specific figures.

    Answer. Janssen is one of the world's top R&D investors in any 
industry, anywhere in the world. In 2018 we invested $8.4 billion in 
pharmaceutical R&D globally. Our pharmaceutical revenue in the U.S. was 
$23.3 billion. We invested 86 percent more in pharmaceutical R&D ($8.4 
billion) than we spent on pharmaceutical global sales and marketing 
($4.5 billion).

    Question. Do you invest more in R&D than you spend on marketing and 
administration? What company functions do you consider to be included 
in administration? Please include specific figures.

    Answer. Johnson & Johnson is comprised of three business segments: 
pharmaceuticals (Janssen), medical devices, and consumer products. In 
its financial statements, Johnson & Johnson reports a global total 
figure across all segments for Sales, Marketing and Administration 
(``SM&A''). This figure combines marketing, sales, and administrative 
expenses such as insurance, legal, finance, and product distribution. 
In 2018, that global, cross-sector SM&A expenditure was $22.54 billion. 
The total global, cross-sector R&D investment by J&J in 2018 was $10.78 
billion.

    Johnson & Johnson does not report SM&A by business segment. 
Janssen, the pharmaceutical segment of J&J, invested $8.4 billion in 
R&D globally in 2018 and spent $4.5 billion on marketing and sales 
globally.

    Question. Do you invest more in R&D than you spend on marketing and 
sales? What company functions do you consider to be included in sales? 
Please include specific figures.

    Answer. In 2018, we invested 86 percent more in pharmaceutical R&D 
($8.4 billion) than we spent on pharmaceutical global sales and 
marketing ($4.5 billion). Sales and marketing includes: (1) our 
expenses related to selling, (2) marketing management, (3) market and 
consumer research, and (4) advertising and promotion.

    Question. Why do you advertise for the drugs you manufacture? What 
factors do you consider in choosing which drugs you advertise?

    Answer. We believe direct-to-consumer communication, including 
advertising, can empower patients with information to help them have 
appropriate discussions with their healthcare providers, including 
dialogue about the risks and benefits of treatment. We provide 
accurate, up-to-date educational materials to help patients facing 
diseases our medicines treat and to help patients who take our 
medicines understand how to use them properly.

    We believe acting ethically and responsibly is not only the right 
thing to do but also the right way to do business. We follow all 
relevant laws and regulations regarding the promotion of prescription 
drug products and submit promotional materials to the U.S. Food and 
Drug Administration at the time of initial publication or 
dissemination.

    We work to communicate in ways that will be most valuable in 
empowering patients to have appropriate dialogue with their healthcare 
providers.

    We consider the availability of information and awareness of 
treatment options. We build a communication plan that can include a 
variety of channels, with direct-to-consumer advertising being one 
channel among many we may use.

                                 ______
                                 

 Janssen Biotech, Inc. Monetary and Product Contributions to U.S.-based
                 Charitable Organizations Full Year 2014
(Payments made from January 1, 2014 to December 31, 2014)--Amended March
                                19, 2019
------------------------------------------------------------------------
                                    Payment
  Donation     Payee      Payee      Amount     Payment    Project Title/
    Type                 Address     (USD)        Date      Description
------------------------------------------------------------------------
Monetary     100       4631           $1,000    8/29/2014  100 Black Men
              Black     Delmar                              of Metro St.
              Men (of   Boulevard                           Louis, St.
              Metro     , St.                               Louis, MO
              St.       Louis, MO
              Louis)    63108
------------------------------------------------------------------------
Monetary     Abington  515              $300    8/29/2014  Abington Art
              Art       Meetingho                           Center,
              Center    use Road                            Jenkintown,
                        Jenkintow                           PA (2014
                        n, PA                               Janssen
                        19046                               Cares
                                                            Volunteer
                                                            Days)
------------------------------------------------------------------------
Monetary     Aldie     11 Welden        $300    9/10/2014  Aldie
              Foundat   Drive                               Foundation,
              ion       Doylestow                           Doylestown,
              Inc.      n, PA                               PA Janssen
                        18901                               Cares
                                                            Volunteer
                                                            Days
------------------------------------------------------------------------
Monetary     American  2600 US        $1,000    4/21/2014  Run for Dad
              Cancer    Highway 1                           Prostate
              Society   North                               Cancer event
                        North                               in Hamilton,
                        Brunswick                           NJ
                        , NJ
                        08902
------------------------------------------------------------------------
Monetary     Arthriti  115 NE         $5,000    8/29/2014  Arthritis
              s         100th                               Foundation,
              Foundat   Suite                               Seattle, WA--
              ion       #350                                Great West
                        Seattle,                            Region JBRs
                        WA 98125
------------------------------------------------------------------------
Monetary     Arthriti  1876           $6,000   11/10/2014  Jingle Bell
              s         Minnehaha                           Run/Walks
              Foundat   Avenue                              Upper
              ion       West St.                            Midwest
                        Paul, MN
                        55104
------------------------------------------------------------------------
Monetary     Arthriti  35 East       $10,000    8/29/2014  AF, Chicago,
              s         Wacker                              IL 2014
              Foundat   Drive                               Heartland
              ion       Suite                               Region
                        2260                                Jingle Bell
                        Chicago,                            Runs and
                        IL 60601                            Walks
------------------------------------------------------------------------
Monetary     Arthriti  4300           $7,000   12/22/2014  Arthritis
              s         McArthur                            Foundation,
              Foundat   Suite 245                           Dallas, TX--
              ion       Dallas,                             JBRs South
                        TX 75209                            Central
                                                            Region
------------------------------------------------------------------------
Monetary     Arthriti  4530 Park      $5,000    8/29/2014  Arthritis
              s         Road                                Foundation,
              Foundat   Charlotte                           Charlotte,
              ion       , NC                                NC--2014
                        29209                               JBRs
------------------------------------------------------------------------
Monetary     Arthriti  4630           $7,500    10/3/2014  Arthritis
              s         Richmond                            Foundation,
              Foundat   Road                                Cleveland,
              ion       Suite 240                           OH JBRs
                        Cleveland
                        , OH
                        44128
------------------------------------------------------------------------
Monetary     Arthriti  800 West      $12,500   11/13/2014  Jingle Bell
              s         Sixth                               Run/Walks,
              Foundat   Street                              Los Angeles
              ion       Suite                               CA
                        1250 Los
                        Angeles,
                        CA 90017
------------------------------------------------------------------------
Monetary     Arthriti  8383 North     $1,000   11/13/2014  Arthritis
              s         Davis                               Foundation,
              Foundat   Highway                             Pensacola,
              ion       Pensacola                           FL--Jacksonv
                        , FL                                ille JBR
                        32514
------------------------------------------------------------------------
Monetary     Arthriti  8383 North     $1,000   11/13/2014  Arthritis
              s         Davis                               Foundation,
              Foundat   Highway                             Pensacola,
              ion       Pensacola                           FL for
                        , FL                                Pensacola
                        32514                               JBR/W
------------------------------------------------------------------------
Monetary     Arthriti  8383 North     $1,500   11/13/2014  Arthritis
              s         Davis                               Foundation,
              Foundat   Highway                             Pensacola,
              ion       Pensacola                           FL--Orlando
                        , FL                                Jingle Bell
                        32514                               Run & Walk
------------------------------------------------------------------------
Monetary     Arthriti  111 South      $2,500    4/18/2014  Walk to Cure
              s         Independe                           Arthritis,
              Foundat   nce Mall                            Philadelphia
              ion,      E Suite                             , PA, May
              Inc.      500                                 17, 2014
                        Philadelp
                        hia, PA
                        19106
------------------------------------------------------------------------
Monetary     Arthriti  115 NE         $5,000     6/9/2014  Eight Walks
              s         100th                               to Cure
              Foundat   Suite                               Arthritis in
              ion,      #350                                the Great
              Inc.      Seattle,                            West Region
                        WA 98125
------------------------------------------------------------------------
Monetary     Arthriti  122 East      $50,000     4/4/2014  NE Region
              s         42nd                                Jingle Bell
              Foundat   Street                              Runs 2014
              ion,      18th
              Inc.      Floor New
                        York, NY
                        10168
------------------------------------------------------------------------
Monetary     Arthriti  1876           $3,500     4/4/2014  Arthritis
              s         Minnehaha                           Foundation's
              Foundat   Avenue                              2014 Walks
              ion,      West St.                            in MN, WI
              Inc.      Paul, MN                            and ND
                        55104
------------------------------------------------------------------------
Monetary     Arthriti  209 10th       $2,000    4/21/2014  Arthritis
              s         Avenue                              Foundation
              Foundat   South                               Walks to
              ion,      Suite 228                           Cure
              Inc.      Nashville                           Arthritis in
                        , TN                                TN and AL
                        37203
------------------------------------------------------------------------
Monetary     Arthriti  29 Crafts      $3,500    4/21/2014  Walks to Cure
              s         Street                              Arthritis in
              Foundat   Suite 450                           CT, RI, NH,
              ion,      Newton,                             and MA
              Inc.      MA 02458
------------------------------------------------------------------------
Monetary     Arthriti  35 East       $12,000    4/21/2014  Walks to Cure
              s         Wacker                              Arthritis in
              Foundat   Drive                               IL, IN, IA,
              ion,      Suite                               KS, MO, NE
              Inc.      2260
                        Chicago,
                        IL 60601
------------------------------------------------------------------------
Monetary     Arthriti  400              $500     6/9/2014  2014 Walk to
              s         Hibiscus                            Cure
              Foundat   Street                              Arthritis,
              ion,      West Palm                           Lake Worth,
              Inc.      Beach, FL                           FL
                        33401
------------------------------------------------------------------------
Monetary     Arthriti  408 12th         $500    4/18/2014  Walk to Cure
              s         Street                              Arthrits,
              Foundat   West                                Sarasota,
              ion,      Bradenton                           FL, May 17,
              Inc.      , FL                                2014
                        34205
------------------------------------------------------------------------
Monetary     Arthriti  4300           $4,000    4/21/2014  South Central
              s         McArthur                            Region Walks
              Foundat   Suite 245                           to Cure
              ion,      Dallas,                             Arthritis
              Inc.      TX 75209
------------------------------------------------------------------------
Monetary     Arthriti  4720          $10,000    4/18/2014  Arthritis
              s         Montgomer                           Walks--Mid
              Foundat   y Lane                              Atlantic
              ion,      Suite 300                           Region--DE,
              Inc.      Bethesda,                           MD, DC, VA,
                        MD 20814                            NC, and SC.
------------------------------------------------------------------------
Monetary     Arthriti  800 West      $10,000    6/25/2014  Walks to Cure
              s         6th                                 Arthritis in
              Foundat   Street                              CA, AZ, and
              ion,      Suite                               HI
              Inc.      1250 Los
                        Angeles,
                        CA 90017
------------------------------------------------------------------------
Monetary     Arthriti  8383 North       $500    3/17/2014  2014 Walk to
              s         Davis                               Cure
              Foundat   Highway                             Arthritis
              ion,      Pensacola                           Pensacola FL
              Inc.      , FL
                        32514
------------------------------------------------------------------------
Monetary     Big       2875 York        $300    6/24/2014  Janssen Cares
              Brother   Road                                Volunteers
              s Big     Jamison,                            Days--Commun
              Sisters   PA 18929                            ity Service
                                                            at Big
                                                            Brothers Big
                                                            Sisters,
                                                            Jamison, PA
------------------------------------------------------------------------
Monetary     Bowmans   1635 River       $300    8/29/2014  Bowman's Hill
              Hill      Road New                            Wild Flower
              Wildflo   Hope, PA                            Preserve,
              wer       18938                               New Hope, PA
              Preserv                                       (2014 JCVD)
              e
------------------------------------------------------------------------
Monetary     Bringing  940 West       $2,500   10/28/2014  Bringing Hope
              Hope      Valley                              Home Inc.,
              Home      Road                                Wayne, PA
              Inc.      Wayne, PA
                        19087
------------------------------------------------------------------------
Monetary     Cancer    121 Avenue     $2,000    4/21/2014  Cancer Care's
              Care,     of the                              6th Annual
              Inc.      Americas                            Healing
                        6th Floor                           Hearts
                        New York,                           Family
                        NY 10013                            Bereavement
                                                            Camp,
                                                            Milford, PA
------------------------------------------------------------------------
Monetary     Cancer    121 Avenue    $10,000    4/21/2014  2014-2015
              Care,     of the                              Edition of
              Inc.      Americas                            ``A Helping
                        6th Floor                           Hand: The
                        New York,                           Resource
                        NY 10013                            Guide for
                                                            People with
                                                            Cancer.''
------------------------------------------------------------------------
Monetary     Cancer    200 Kirk         $600    6/25/2014  Janssen Cares
              Support   Road                                Volunteer
              Communi   Warminste                           Days--commun
              ty        r, PA                               ity service
              Gilda's   18974                               at Gilda's
              Club                                          Club June 24
              Warmins                                       and June 26,
              ter, PA                                       2014
------------------------------------------------------------------------
Monetary     Cancer    4100           $2,500    10/3/2014  Cancer
              Support   Chamounix                           Support
              Communi   Drive                               Community of
              ty of     Philadelp                           Philadelphia
              Philade   hia, PA                             ,
              lphia     19131                               Warminister,
                                                            PA
------------------------------------------------------------------------
Monetary     Children  34th and       $5,000    10/3/2014  CHOP
              s         Civic                               Philadelphia
              Hospita   Center                              , PA Child
              l of      Blvd.                               Life Program
              Philade   Philadelp
              lphia     hia, PA
              Foundat   19104-
              ion       4399
------------------------------------------------------------------------
Monetary     Chrohn's  386 Park      $15,000    8/29/2014  Crohn's and
              and       Avenue                              Colitis
              Colitis   South                               Foundation,
              Foundat   17th                                New York,
              ion       Floor New                           NY--Camp
                        York, NY                            Oasis
------------------------------------------------------------------------
Monetary     Communit  300B          $20,000   10/15/2014  Community
              y         Lawrence                            Volunteers
              Volunte   Drive                               in Medicine,
              ers in    West                                West
              Medicin   Chester,                            Chester, PA
              e Inc.    PA 19380
------------------------------------------------------------------------
Monetary     Crohns    116 Wilson     $5,000   11/13/2014  Buds N Suds
              and       Pike                                Benefit
              Colitis   Circle                              Concert
              Foundat   Brentwood                           Nashville,
              ion of    , TN                                TN
              America   37027
------------------------------------------------------------------------
Monetary     Crohns    116 Wilson     $5,000   11/13/2014  Donate A
              and       Pike                                Photo
              Colitis   Circle                              Awareness
              Foundat   Brentwood                           Campaign at
              ion of    , TN                                ACG Fall
              America   37027                               2014
------------------------------------------------------------------------
Monetary     Crohns    386 Park     $135,000    4/22/2014  Take Steps
              and       Avenue                              Walks
              Colitis   South                               Nationwide
              Foundat   17th
              ion of    Floor New
              America   York, NY
------------------------------------------------------------------------
Monetary     Crohns    9 Lake         $3,000    4/18/2014  CCFA 's Camp
              and       Bellevue                            Oasis for
              Colitis   Drive                               IBD
              Foundat   Suite 203                           Pediatric
              ion of    Bellevue,                           Patients,
              America   WA 98005                            Longbranch,
                                                            WA
------------------------------------------------------------------------
Monetary     Crohn's   386 Park       $5,000    8/29/2014  CCFA, NY, NY
              and       Avenue                              (DDW
              Colitis   South                               Awareness)
              Foundat   17th
              ion of    Floor New
              America   York, NY
------------------------------------------------------------------------
Monetary     Delaware  215 South      $3,000    9/10/2014  Delaware
              Valley    16th                                Valley
              Science   Street,                             Science
              Council   Philadelp                           Council,
                        hia PA                              STEM
                        19102                               Programs
------------------------------------------------------------------------
Monetary     Delaware  215 South     $21,300     4/4/2014  Delaware
              Valley    16th                                Valley
              Science   Street,                             Science
              Fairs,    Philadelp                           Fairs Tri-
              Inc.      hia PA                              State
                        19102                               Competition,
                                                            Oaks, PA
------------------------------------------------------------------------
Monetary     Educatio  454 Maple      $5,000    10/3/2014  Education-
              n-Plus    Terrace                             Plus Inc.,
              Inc.      Ardmore,                            Philadelphia
                        PA                                  , PA Read
                                                            Now Program
------------------------------------------------------------------------
Monetary     Franklin  222 North     $10,000    10/3/2014  Franklin
              Institu   20th                                Institute,
              te        Street                              Philadelphia
                        Philadelp                           , PA
                        hia, PA
                        19103
------------------------------------------------------------------------
Monetary     Girl      330 Manor      $4,000    10/3/2014  Girl Scouts
              Scouts    Road                                of Eastern
              of        Miquon,                             PA, Miquon,
              Eastern   PA 19444                            PA
              Pennsyl
              vania
              Inc.
------------------------------------------------------------------------
Monetary     Green     1368          $15,000    10/3/2014  Green
              Valleys   Prizer                              Valleys,
              Assocat   Road                                Pottstown,
              ion of    Pottstown                           PA (EITC
              Southea   , PA                                participant)
              stern     19465
              Pennsyl
              vania
------------------------------------------------------------------------
Monetary     Hatboro   440 South        $300     9/4/2014  Hatboro Area
              Area      York Road                           YMCA,
              YMCA      Hatboro,                            Hatboro, PA
                        PA 19040                            (2014 Jansen
                                                            Cares V.D.)
------------------------------------------------------------------------
Monetary     Hatboro   229              $300    8/29/2014  Hatboro-
              Horsham   Meetingho                           Horsham
              Educati   use Road                            Educational
              onal      Hatboro-                            Foundation,
              Foundat   Horsham,                            Horsham, PA
              ion       PA 19044
------------------------------------------------------------------------
Monetary     Hatboro   229           $25,000    8/29/2014  Hatboro-
              Horsham   Meetingho                           Horsham Ed.
              Educati   use Road                            Foundation
              onal      Hatboro-                            (EITC),
              Foundat   Horsham,                            Horsham, PA
              ion       PA 19044
------------------------------------------------------------------------
Monetary     Impact    2979             $300    8/29/2014  JBI Impact
              Thrift    Bethlehem                           Thrift
              Sortes    Pike                                Sortes,
              Inc.      Montgomer                           Inc.,
                        yville,                             Montgomeryvi
                        PA                                  lle, PA
------------------------------------------------------------------------
Monetary     Integrat  532            $1,000     4/4/2014  2014 Belmont
              ed        Broadholl                           Stakes Blue
              Medical   ow Road                             Ribbon Run
              Foundat   Suite                               for Prostate
              ion,      142A                                Cancer,
              Inc.      Melville,                           Melville, NY
                        NY 11747
------------------------------------------------------------------------
Monetary     Internat  6144 Clark    $10,000   12/24/2014  International
              ional     Center                              Waldenstroms
              Waldens   Avenue                              Macroglobuli
              troms     Sarasota,                           nemia
              Macrogl   FL 34238                            Foundation,
              obuline                                       Sarasota, FL
              mia
              Foundat
              ion
------------------------------------------------------------------------
Monetary     Junior    522 South      $5,000    10/3/2014  Junior
              Achieve   Walnut                              Achievement,
              ment of   Street                              Wayne, PA
              Delawar   Wilmingto                           (Horsham
              e         n, DE                               Scools)
              Valley    19801
------------------------------------------------------------------------
Monetary     Leukemia  555 North    $175,000    6/16/2014  LLS
              and       Lane                                Nationwide
              Lympho    Suite                               Light the
              Society   5010                                Night Walks
              , Inc.    Conshohoc
                        ken, PA
                        19428
------------------------------------------------------------------------
Monetary     Metropol  2323          $15,000    10/3/2014  MANNA,
              itan      Ranstead                            Philadelphia
              Area      Street                              , PA
              Neighbo   Philadelp
              rhood     hia, PA
              Nurtrit   19103
              ion
              Allianc
              e
------------------------------------------------------------------------
Monetary     National  PO Box 303     $2,500    8/29/2014  National
              Ovarian   Holicong,                           Ovarian
              Cancer    PA 18928                            Cancer
              Coaliti                                       Coalition
              on Inc.                                       Inc.,
                                                            Holicong, PA
------------------------------------------------------------------------
Monetary     National  6600 SW       $50,000   11/13/2014  National
              Psorias   2nd                                 Psoriasis
              is        Avenue                              Foundation,
              Foundat   Suite 300                           Portland OR--
              ion       Portland,                           Compliments
                        OR 97223                            are
                                                            Contagious
------------------------------------------------------------------------
Monetary     Open      350 Main         $300    8/29/2014  Royersford
              Door      Street                              Outreach
                        Royersfor                           Open Door
                        d, PA                               (Janssen
                        19468                               Cares V.D.),
                                                            Royersford,
                                                            PA
------------------------------------------------------------------------
Monetary     Perkiome  1 West           $300    8/29/2014  Perkioment
              n         Skippack                            Watershed
              Watersh   Pike                                Conservancy,
              ed        Schwenksv                           Schwenksvill
              Conserv   ille, PA                            e, PA
              ancy      19473
------------------------------------------------------------------------
Monetary     Philadel  325           $10,000    10/3/2014  Philadelphia
              phia      Chestnut                            Reads, Inc.,
              Reads,    Street                              Philadelphia
              Inc.      Philadelp                           , PA (EITC)
                        hia, PA
                        19106
------------------------------------------------------------------------
Monetary     Premier   PO Box 93      $5,000    10/3/2014  Premier Cares
              Cares     Pleasant                            Foundation,
              Foundat   Valley,                             Inc.
              ion       NY 12569
              Inc.
------------------------------------------------------------------------
Monetary     Prostate  7009 S.        $1,000    8/29/2014  Prostate
              Cancer    Potomac                             Cancer
              Educati   Street                              Education
              on        Centennia                           Council,
              Council   l, CO                               Centennial,
                        80112                               CO
------------------------------------------------------------------------
Monetary     Prostate  500           $10,000    4/21/2014  Prostate
              Health    Victory                             Health
              Educati   Road                                Education
              on        Quincy,                             Network
              Network   MA 02170                            (PHEN) Sixth
              , Inc.                                        Annual
                                                            Father's Day
                                                            Rally
                                                            Nationwide
------------------------------------------------------------------------
Monetary     Rebuidli  PO Box         $5,000    6/13/2014  Mantua Block
              ng        42752                               Build,
              Togethe   Philadelp                           Philadelphia
              r         hia, PA                             , PA
              Philade   19101-
              lphia     2752
------------------------------------------------------------------------
Monetary     Retired   925            $7,000   10/15/2014  RSVP, Blue
              Senior    Harvest                             Bell, PA
              Volunte   Drive
              er        Suite 100
              Program   Blue
              of        Bell, PA
              Montgom   19422
              ery
              County
------------------------------------------------------------------------
Monetary     Riverben  1950           $5,000     6/9/2014  Outreach to
              d         Spring                              Children/
              Environ   Mill Road                           Access to
              mental    Gladwyne,                           Nature
              Educati   PA 19035                            Education
              on                                            for local
              Center                                        elementary
                                                            school in
                                                            Norristown,
                                                            PA
------------------------------------------------------------------------
Monetary     Special   2800           $4,000   12/31/2014  Special
              Equestr   Street                              Equestrians,
              ians      Road                                Warrington,
                        Warringto                           PA
                        n, PA
                        18976
------------------------------------------------------------------------
Monetary     The       34th           $2,000    4/18/2014  5th Annual
              Childre   Street                              Walk for
              ns        Civic                               Hope,
              Hospita   Center                              Veteran's
              l of      Boulevard                           Park,
              Philade   Philadelp                           Hamilton,
              lphia     hia, PA                             NJ,
              Foundat   19104                               benefitting
              ion                                           IBD Research
                                                            at CHOP
------------------------------------------------------------------------
Monetary     The       4275           $3,000     6/9/2014  Hands-On
              Giving    County                              Helping by
              Tree      Line Road                           Children
                        Suite 138
                        Chalfont,
                        PA 18914
------------------------------------------------------------------------
Monetary     The       2600          $10,000    4/21/2014  Hubert J. P.
              Melmark   Wayland                             Schoemaker
              Charita   Road                                Classic,
              ble       Berwyn,                             October 6,
              Foundat   PA 19312                            2014,
              ion                                           Berwyn, PA
------------------------------------------------------------------------
Monetary     Trustees  University     $7,000   10/15/2014  WXPN (Trutees
              of the    of                                  of the U of
              Univers   Pennsylva                           PA),
              ity of    nia                                 Philadelphia
              Pennsyl   Philadelp                           , PA
              vania     hia, PA
                        19104
------------------------------------------------------------------------
Monetary     United    1709         $223,382   12/22/2014  United Way
              Way of    Benjamin                            Campaign
              Greater   Franklin                            Match
              Philade   Parkway
              lphia     Philadelp
              and       hia, PA
              Souther   19103
              n New
              Jersey
------------------------------------------------------------------------
Monetary     Us Too    5003           $1,000    9/10/2014  Us Too
              Interna   Fairview                            Internationa
              tional    Ave.                                , Des
                        Downers                             Plaines, IL
                        Grove, IL
                        60515
------------------------------------------------------------------------
Monetary     Wissahic  12 Morris      $2,603    6/25/2014  New
              kon       Road                                wildflower
              Valley    Ambler,                             meadow
              Watersh   PA 19002                            development
              ed                                            via Janssen
              Associa                                       Cares
              tion                                          Volunteer
                                                            Days.
------------------------------------------------------------------------
Monetary     Wissahic  12 Morris      $1,400    4/21/2014  Community
              kon       Road                                Service
              Valley    Ambler,                             Project for
              Watersh   PA 19002                            JBI's Bridge
              ed                                            to
              Associa                                       Employment
              tion,                                         program;
              Inc.                                          mentors and
                                                            students
                                                            planting
                                                            trees and
                                                            shrubs for
                                                            water
                                                            conservation
                                                            at
                                                            Wissahickon
                                                            Valley
                                                            Watershed
------------------------------------------------------------------------
Janssen has also made financial donations to independent charitable
  foundations that assist patients who are underinsured and in financial
  need with treatment-related expenses. In keeping with our donor
  agreements and applicable regulatory guidance, we will only disclose
  aggregate data on our charitable giving and do not publicize
  information on donations to specific foundations and disease states.
  In 2014, we contributed approximately $40 million in donations to
  independent charitable foundations, enabling them to provide
  assistance with medication-related copays to patients with cancer
  diseases.


----------------------------------------------------------------------------------------------------------------
 
----------------------------------------------------------------------------------------------------------------
Product               Johnson & Johnson     One Johnson &          $84,591,419    3/15/2013  Patient Assistance
                       Patient Assistance    Johnson Plaza, New                               Product Donation
                       Foundation            Brunswick, NJ 08933
----------------------------------------------------------------------------------------------------------------
Product               Johnson & Johnson     One Johnson &          $86,924,535    6/15/2013  Patient Assistance
                       Patient Assistance    Johnson Plaza, New                               Product Donation
                       Foundation            Brunswick, NJ 08933
----------------------------------------------------------------------------------------------------------------
Product               Johnson & Johnson     One Johnson &          $78,551,321    9/15/2013  Patient Assistance
                       Patient Assistance    Johnson Plaza, New                               Product Donation
                       Foundation            Brunswick, NJ 08933
----------------------------------------------------------------------------------------------------------------
Product               Johnson & Johnson     One Johnson &          $86,312,829   12/15/2013  Patient Assistance
                       Patient Assistance    Johnson Plaza, New                               Product Donation
                       Foundation            Brunswick, NJ 08933
----------------------------------------------------------------------------------------------------------------
Updatd February 24, 2017


Janssen Pharmaceuticals, Inc. Monetary and Product Contributions to U.S.-
              based Charitable Organizations Full Year 2014
        (Payments made from January 1, 2014 to December 31, 2014)
------------------------------------------------------------------------
                                                               Project
 Donation    Payee     Payee   Payment Amount    Payment       Title/
   Type               Address       (USD)          Date      Description
------------------------------------------------------------------------
Monetary    180      1                 $1,000    9/22/2014  Youth
             Turnin   Bethany                                Helpline
             g        Road,                                  Hunterdon,
             Lives    Buildin                                Mercer, and
             Around   g 3                                    Somerset
             , Inc.   Suite                                  Operations
                      42
                      Hazlet,
                      NJ
                      07730
------------------------------------------------------------------------
Monetary    A        P.O. Box          $2,500    12/4/2014  A Woman's
             Woman'   299                                    Place
             s        Doylest                                Prevention
             Place    own, PA                                Project
                      18901
------------------------------------------------------------------------
Monetary    Adult    872 E               $300     8/4/2014  Cost
             Day      Main                                   associated
             Center   Street                                 with 2014
             of       Bridgew                                Janssen
             Somers   ater,                                  Cares
             et       NJ                                     volunteer
             County   08807                                  activity
------------------------------------------------------------------------
Monetary    Allies,  1262              $7,500   11/17/2014  Greensleeves
             Inc.     Whiteho                                Flemington
                      rse-                                   Expansion
                      Hamilto                                Environment
                      n                                      al
                      Square                                 Stewardship
                      Road                                   Program
                      Buildin
                      g A,
                      Suite
                      101
                      Hamilto
                      n, NJ
                      08690
------------------------------------------------------------------------
Monetary    America  100 West          $5,000    5/27/2014  2014 EXPO
             n        Station                                Pittsburgh
             Diabet   Square
             es       Drive
             Associ   Suite
             ation    1900
                      Pittsbu
                      rgh, PA
                      15219
------------------------------------------------------------------------
Monetary    America  1160             $30,000   12/10/2014  Diabetes
             n        Route                                  Interventio
             Diabet   22 East                                n Project
             es       Suite                                  ($20,000),
             Associ   103                                    and
             ation    Bridege                                Community
                      water,                                 Outreach
                      NJ                                     Education
                      08807                                  ($10,000)
------------------------------------------------------------------------
Monetary    America  1701            $125,000   12/10/2014  American
             n        North                                  Diabetes
             Diabet   Beaureg                                Association
             es       ard                                    's Outcomes-
             Associ   Street                                 based
             ation    Alexand                                Community
                      ria, VA                                Programs
                      22311                                  Targeted to
                                                             High Risk
                                                             Populations
------------------------------------------------------------------------
Monetary    America  1 Union           $5,000   10/16/2014  Fundraising
             n        Street                                 event
             Heart    Suite                                  support to
             Associ   301                                    benefit
             ation    Robbins                                general
                      ville,                                 mission of
                      NJ                                     organizatio
                      08691                                  n.
------------------------------------------------------------------------
Monetary    America  1000             $20,000   12/10/2014  Partnership
             n        Wilson                                 for
             Psychi   Bouleva                                Workplace
             atric    rd                                     Mental
             Founda   Suite                                  Health ICU:
             tion     1825                                   Improving
                      Arlingt                                Emotional
                      on, VA                                 Health
                      22208
------------------------------------------------------------------------
Monetary    America  1000            $100,000   12/10/2014  Typical or
             n        Wilson                                 Troubled?
             Psychi   Bouleva                                Student
             atric    rd                                     Mental
             Founda   Suite                                  Health
             tion     1825                                   Education
                      Arlingt                                Program
                      on, VA
                      22208
------------------------------------------------------------------------
Monetary    America  1000            $225,000   12/10/2014  Campaign by
             n        Wilson                                 Psychiatris
             Psychi   Bouleva                                ts and
             atric    rd                                     Judges to
             Founda   Suite                                  Reduce the
             tion     1825                                   Overreprese
                      Arlingt                                ntation of
                      on, VA                                 Incarserate
                      22208                                  d
                                                             Individuals
                                                             with SMI
------------------------------------------------------------------------
Monetary    America  707              $15,000   10/20/2014  Support for
             n Red    Alexand                                the
             Cross    er Road                                American
                      Princet                                Red Cross
                      on, NJ                                 Disaster
                      08550                                  Cycle
                                                             Services
                                                             Program
------------------------------------------------------------------------
Monetary    America  Central          $20,000    3/14/2014  Support to
             n Red    New                                    American
             Cross    Jersey                                 Red Cross
                      707                                    Disaster
                      Alexand                                Relief
                      er Road                                Services
                      Suite
                      101
                      Princet
                      on, NJ
                      08540-
                      6331
------------------------------------------------------------------------
Monetary    Anchor   482                 $418     1/9/2014  General
             House,   Centre                                 Operating
             Inc.     Street                                 Support
                      Trenton
                      , NJ
                      08611
------------------------------------------------------------------------
Monetary    Anderso  PO Box           $17,500   10/22/2014  Integrated
             n        134 532                                Care
             House    County                                 Management
                      Rd. 523
                      Whiteho
                      use, NJ
                      08889
------------------------------------------------------------------------
Monetary    Ann      595 West          $9,500    12/4/2014  Ann
             Silver   State                                  Silverman
             man      Street                                 Community
             Commun   Doylest                                Health
             ity      own, PA                                Clinic for
             Health   18901                                  Bucks
             Clinic                                          County
                                                             residents
------------------------------------------------------------------------
Monetary    Arc of   141               $5,000    9/22/2014  Fundraising
             Somers   South                                  event
             et       Main                                   support to
             County   Street                                 benefit
                      Manvill                                general
                      e, NJ                                  mission of
                      08835                                  organizatio
                                                             n
------------------------------------------------------------------------
Monetary    Arc of   141               $4,000    10/1/2014  Respite
             Somers   South                                  Services
             et       Main                                   for
             County   Street                                 Families
                      Manvill                                with
                      e, NJ                                  Children
                      08835                                  with
                                                             Disabilitie
                                                             s
------------------------------------------------------------------------
Monetary    Arthrit  500 E.            $1,500     7/1/2014  The
             is       Morehea                                Community
             Servic   d                                      Arthritis/
             es       Street                                 Diabetes
                      Suite                                  Project--ta
                      320                                    rgeting
                      Charlot                                women with
                      te, NC                                 Type II
                      28202                                  Diabetes
------------------------------------------------------------------------
Monetary    Asian    180 W             $2,000    8/28/2014  Cardiovascul
             Health   Washing                                ar Health
             Coalit   ton                                    Screenings
             ion      Street                                 for Low-
                      Suite                                  Income,
                      1000                                   Limited-
                      Chicago                                English
                      , IL                                   Speaking At-
                      60602                                  Risk
                                                             Diabetic
                                                             Asian
                                                             Immigrants
                                                             and
                                                             Refugees in
                                                             Chicago
------------------------------------------------------------------------
Monetary    Associa  819               $9,000    8/15/2014  Parital Care
             tion     Alexand                                Rehabilitat
             for      er Road                                ion and
             Advanc   Princet                                Support
             ement    on, NJ                                 Services
             of       08540
             Mental
             Health
------------------------------------------------------------------------
Monetary    Associa  2400 N           $20,000   11/17/2014  Spirit of
             tion     Street                                 the Heart:
             of       NW                                     Community
             Black    Sutie                                  Inverventio
             Cardio   249                                    n to
             logist   Washing                                Improve
             s        ton, DC                                Cardiovascu
                      20037                                  lar Health
                                                             of
                                                             Underserved
                                                             Patients
                                                             with AFIB
------------------------------------------------------------------------
Monetary    Athens   7 N.              $2,500     6/6/2014  The
             Mental   Congres                                Gathering
             Health   s St                                   Place case
             , Inc.   Athens,                                management
                      OH                                     services
                      45701                                  program for
                                                             community
                                                             drop-in
                                                             center for
                                                             adults with
                                                             mental
                                                             illness
------------------------------------------------------------------------
Monetary    Autism   1060              $1,000    8/28/2014  Community
             Speaks   State                                  Partner
                      Road                                   15th Annual
                      2nd                                    Central New
                      Floor                                  Jersey Walk
                      Princet                                Now for
                      on, NJ                                 Autism
                      08540                                  Speaks
------------------------------------------------------------------------
Monetary    B More   5 East            $5,000    8/15/2014  Support of
             Clubho   Frankli                                B'More
             use,     n                                      Clubhouse
             Inc.     Street                                 which
                      Baltimo                                offers
                      re, MD                                 members
                      21202                                  meaningful
                                                             work,
                                                             friendship,
                                                             and links
                                                             to stable
                                                             housing,
                                                             education
                                                             and other
                                                             resources
------------------------------------------------------------------------
Monetary    Bay      66 Canal          $5,000    6/12/2014  Bay Cove
             Cove     Street                                 Wellness
             Human    Boston,                                Center to
             Servic   MA                                     assist
             es,      02114                                  diverse low-
             Inc.                                            income
                                                             clients who
                                                             are working
                                                             towards
                                                             recovery
                                                             from severe
                                                             mental
                                                             illness
------------------------------------------------------------------------
Monetary    Bear     1162                $500   10/15/2014  Bear Tavern
             Tavern   Bear                                   Elementary
             Parent   Tavern                                 School
             s        Road                                   Science
             Associ   Titusvi                                Fair
             ation    lle, NJ
                      08560
------------------------------------------------------------------------
Monetary    Big      2875              $6,500   10/14/2014  School-Based
             Brothe   York                                   Mentoring
             rs Big   Road                                   Program
             Sister   Jamison
             s of     , PA
             Bucks    18929
             County
------------------------------------------------------------------------
Monetary    Big      2 West            $7,500    10/1/2014  Big Brothers
             Brothe   Washing                                Big Sisters
             rs Big   ton                                    Youth
             Sister   Avenue                                 Mentoring
             s Of     Suite                                  Program-
             Hunter   210 PO                                 Somerset
             don      Box 123                                County
             Somers   Washing
             et and   ton, NJ
             Warren   07882
             County
------------------------------------------------------------------------
Monetary    Big      535 East          $8,000    8/26/2014  Big Brothers
             Brothe   Frankli                                Big Sisters
             rs Big   n                                      of Mercer
             Sister   Street                                 County
             s of     Trenton                                Youth
             Mercer   , NJ                                   Mentoring
             County   08610                                  Program
------------------------------------------------------------------------
Monetary    Boys     212              $22,500   10/14/2014  Career
             and      Centre                                 Launch
             Girls    Street                                 (Career
             Club     Trenton                                Exploration
             of       , NJ                                   , Work
             Trento   08611                                  Readiness,
             n and                                           HS
             Mercer                                          Graduation,
             County                                          and Career
                                                             Pathway
                                                             Program)
------------------------------------------------------------------------
Monetary    Bridgeh  950 S.            $4,000    6/12/2014  Recovery
             aven,    First                                  Connection
             Inc.     Street                                 program
                      Louisvi
                      lle, KY
                      40203
------------------------------------------------------------------------
Monetary    Bridgew  615 N.            $5,000    12/4/2014  Self-
             ay       Broad                                  Sufficiency
             Rehabi   Street                                 Fund for
             litati   Elizabe                                Somerset,
             on       th, NJ                                 Mercer and
             Servic   07208                                  Hunterdon
             es                                              residents
------------------------------------------------------------------------
Monetary    Bristol  120               $7,500   12/10/2014  ArtRageous
             Rivers   Radclif                                Summer Camp
             ide      fe
             Theate   Street
             r Co,    P O Box
             Inc.     1250
                      Bristol
                      , PA
                      19007
------------------------------------------------------------------------
Monetary    Broward  305              $10,000    5/27/2014  Affordable
             County   Southea                                Rental
             Commun   st 18th                                Housing
             ity      Court                                  program
             Develo   Fort
             pment    Lauderd
             Corpor   ale, FL
             ation    33316
             , Inc.
------------------------------------------------------------------------
Monetary    Bucks    1069              $5,000   11/17/2014  Bucks County
             County   Jackson                                Housing
             Housin   ville                                  Group's
             g        Road                                   Veterans
             Group    Ivyland                                Housing
                      , PA                                   Assistance
                      18974                                  Program
------------------------------------------------------------------------
Monetary    Catholi  Diocese           $5,000     7/1/2014  On My Own--
             c        of                                     Supportive
             Charit   Trenton                                Housing
             ies      Delawar                                Program
                      e House                                Services
                      Mental                                 program
                      Health
                      Service
                      s 25
                      Ikea
                      Drive
                      Westham
                      pton,
                      NJ
                      08060
------------------------------------------------------------------------
Monetary    Catholi  Diocese          $17,500     7/7/2014  Partners In
             c        of                                     Recovery
             Charit   Trenton                                program
             ies      Delawar
                      e House
                      Mental
                      Health
                      Service
                      s 25
                      Ikea
                      Drive
                      Westham
                      pton,
                      NJ
                      08060
------------------------------------------------------------------------
Monetary    Catholi  212                  $75    1/28/2014  Employee
             c        Ninth                                  directed
             Charit   Street                                 donation in
             ies      Pittsbu                                lieu of
             Dioces   rgh,                                   company
             e of     Pennsyl                                holiday
             Pittsb   vania                                  gift
             urgh     15222
------------------------------------------------------------------------
Monetary    Catholi  212                  $75    12/3/2014  Employee
             c        Ninth                                  directed
             Charit   Street                                 donation in
             ies      Pittsbu                                lieu of
             Dioces   rgh,                                   company
             e of     Pennsyl                                holiday
             Pittsb   vania                                  gift
             urgh     15222
------------------------------------------------------------------------
Monetary    Catholi  920               $4,000   10/16/2014  CYO's Broad
             c        South                                  St. Trenton
             Youth    Broad                                  Center
             Organi   Street                                 After
             zation   Trenton                                School
             of       , NJ                                   Program's
             Mercer   08611                                  (ASP)
             County                                          Tutoring
                                                             Project
------------------------------------------------------------------------
Monetary    Center   11                  $300     8/4/2014  Cost
             for      Minneak                                associated
             Educat   oning                                  with 2014
             ional    Road                                   Janssen
             Advanc   Fleming                                Cares
             ement    ton, NJ                                volunteer
                      08822                                  activity
------------------------------------------------------------------------
Monetary    Center   11               $15,000   10/20/2014  Employment
             for      Minneak                                Training
             Educat   oning                                  program
             ional    Road                                   enhancement
             Advanc   Fleming                                s
             ement    ton, NJ
                      08822
------------------------------------------------------------------------
Monetary    Center   Harzfeld         $10,000    9/16/2014  PAINS:
             for      Buildin                                National
             Practi   g 1111                                 Pain
             cal      Main                                   Strategy
             Bioeth   Street,                                Roll-Out
             ics      Suite                                  Meeting
                      500
                      Kansas
                      City,
                      MO
                      64105-2
                      116
------------------------------------------------------------------------
Monetary    Chabad   PO Box            $1,000     5/9/2014  ``We Care''
             Lubavi   29                                     Educational
             tch of   Princet                                Series
             Mercer   on, NJ
             County   08542
             , Inc.
------------------------------------------------------------------------
Monetary    Child    204 N.            $2,000    10/1/2014  Adolescent
             Home     West                                   Prenatal
             and      Street                                 and
             Commun   #101                                   Parenting
             ity      Doylest                                Continuum
                      own, PA
                      18901
------------------------------------------------------------------------
Monetary    Childre  635              $10,000   10/20/2014  CUNA and
             n's      South                                  Body and
             Home     Clinton                                Soul
             Societ   Avenue                                 Prenatal
             y of     Trenton                                Health
             New      , NJ                                   Education
             Jersey   08611                                  Program
------------------------------------------------------------------------
Monetary    Childre  Roebling          $5,000     5/7/2014  Fundraising
             n's      Market                                 event
             Home     Complex                                support to
             Societ   635                                    benefit
             y of     South                                  general
             New      Clinton                                mission of
             Jersey   Avenue                                 organizatio
                      Trenton                                n
                      , NJ
                      08611-
                      1831
------------------------------------------------------------------------
Monetary    Christi  PO Box            $2,500    12/3/2014  Pajama Bags
             nes      190                                    for Kids in
             Hope     Hopewel                                Need in
             for      l, NJ                                  Mercer
             Kids     08525                                  County
             Founda
             tion
------------------------------------------------------------------------
Monetary    College  2000             $22,500   10/14/2014  Nursing
             of New   Penning                                Merit
             Jersey   ton                                    Scholarship
                      Road                                   s ($10,000)
                      P.O.                                   and
                      Box                                    Educational
                      7718                                   Opportunity
                      Ewing,                                 Fund
                      NJ                                     Promise
                      08628                                  Awards
                                                             ($12,500)
------------------------------------------------------------------------
Monetary    Colorad  PO Box            $2,500     8/1/2014  Peer
             o        6336                                   Workforce
             Mental   Denver,                                Initiative
             Wellne   CO
             ss       80206
             Networ
             k
------------------------------------------------------------------------
Monetary    Communi  PO Box            $5,000   11/17/2014  Rise Summer
             ty       88 116                                 Healthy
             Action   North                                  Food
             Servic   Main                                   Initiative
             e        Street                                 for low
             Center   Hightst                                income
             , Inc.   own, NJ                                youth
                      08520
------------------------------------------------------------------------
Monetary    Communi  4059              $5,000   10/23/2014  Arts for
             ty       Skyron                                 Seniors
             Conser   Drive                                  ($3,000)
             vatory   Doylest                                and Music
             of       own, PA                                Therapy
             Music    18902                                  ($2,000)
------------------------------------------------------------------------
Monetary    Communi  PO Box          $150,000   12/12/2014  Johnson &
             ty       338                                    Johnson
             Founda   Morrist                                Somerset
             tion     own, NJ                                County
             of New   07963                                  Contributio
             Jersey                                          ns Fund to
                                                             support
                                                             healthcare
                                                             and basic
                                                             needs of
                                                             residents
                                                             in Somerset
                                                             and
                                                             Hunterdon
                                                             Counties
------------------------------------------------------------------------
Monetary    Communi  P.O. Box         $11,500   10/13/2014  Each One,
             ty       15176                                  Teach One:
             Health   407                                    An Evidence
             Coalit   Crutchf                                Based
             ion,     ield                                   Diabetes
             Inc.     Street                                 Self-
                      Durham,                                Management
                      NC                                     Workshop
                      27704                                  and
                                                             Community
                                                             Leaders
                                                             Training
------------------------------------------------------------------------
Monetary    Communi  199              $12,000    5/27/2014  Pathway to
             ty       Pomeroy                                Recovery
             Hope,    Road                                   residential
             Inc.     Parsipp                                programs
                      any, NJ                                ($10,000)
                      07054                                  and The
                                                             Mental
                                                             Health
                                                             Educational
                                                             Forum and
                                                             Wellness
                                                             Fair
                                                             ($2,000)
------------------------------------------------------------------------
Monetary    Communi  199              $13,000    11/5/2014  Hope for
             ty       Pomeroy                                Veterans
             Hope,    Road                                   and Valley
             Inc.     Parsipp                                Brook
                      any, NJ                                Village for
                      07054                                  Veterans
------------------------------------------------------------------------
Monetary    Communi  310 W.            $7,500   10/20/2014  Social
             ty       State                                  Security
             Justic   Street                                 Services
             e        3rd                                    and
             Center   Floor                                  Veterans
             , Inc.   Trenton                                Assistance
                      , NJ                                   Project
                      08618
------------------------------------------------------------------------
Monetary    Communi  507 E.            $4,000     7/1/2014  Compeer
             ty       College                                Program of
             Mental   Street                                 Johnson
             Health   Iowa                                   County
             Center   City,
             For      IA
             Mid-     52240
             Easter
             n Iowa
             dba
             Compee
             r
             Progra
             m,
             Inc.
------------------------------------------------------------------------
Monetary    Compeer  259               $2,500    7/29/2014  Compeer
             Roches   Monroe                                 Rochester
             ter,     Avenue                                 Youth and
             Inc.     Rochest                                Family
                      er, NY                                 Mentoring
                      14607                                  Program
------------------------------------------------------------------------
Monetary    Compeer  259               $3,000     7/1/2014  Compeer
             , Inc.   Monroe                                 Senior
                      Avenue                                 Partners
                      Suite                                  program
                      340
                      Rochest
                      er, NY
                      14607
------------------------------------------------------------------------
Monetary    Contact  60 S.             $8,500    12/4/2014  CRISIS
             of       Main                                   HOTLINES
             Mercer   Street                                 and Online
             County   Penning                                Emotional
             New      ton, NJ                                Support:
             Jersey   08534                                  CRISIS CHAT
             , Inc.                                          and
                                                             TxtToday
------------------------------------------------------------------------
Monetary    Contact  60 South          $1,000    3/17/2014  Annual
             of       Main                                   Senior
             Mercer   Street                                 Volunteer
             County   Penning                                Recognition
             New      ton, NJ                                Brunch,
             Jersey   08534                                  ``Volunteer
             , Inc.                                          s Are
                                                             Heroes!''
------------------------------------------------------------------------
Monetary    Court    1450             $12,500   10/14/2014  CASA of
             Appoin   Parksid                                Mercer
             ted      e                                      Child
             Specia   Avenue                                 Advocacy
             l        Suite                                  Program for
             Advoca   22                                     Abused and
             tes      Ewing,                                 Neglected
                      NJ                                     Children
                      08638
------------------------------------------------------------------------
Monetary    D&R      P.O. Box            $250     2/3/2014  23rd Annual
             Canal    2 Rocky                                D&R Canal
             Watch    Hill,                                  Watch 5K
                      NJ                                     Fun Run
                      08553
------------------------------------------------------------------------
Monetary    Deborah  212               $1,000    8/28/2014  2015 Women's
             Hospit   Trenton                                Heart
             al       Road                                   Health
             Founda   Browns                                 Symposium
             tion     Mills,
                      NJ
                      08015
------------------------------------------------------------------------
Monetary    Delawar  14                  $300     8/4/2014  Cost
             e        Michael                                associated
             River    McCorri                                with 2014
             Steamb   stin                                   Janssen
             oat      Road                                   Cares
             Floati   Hamilto                                volunteer
             ng       n, NJ                                  activity
             Classr   08690
             oom,
             Inc.
------------------------------------------------------------------------
Monetary    Delawar  14                $4,000    11/3/2014  Environmenta
             e        Michael                                l education
             River    McCorri                                for
             Steamb   stin                                   underfunded
             oat      Road                                   and
             Floati   Hamilto                                underserved
             ng       n, NJ                                  schools and
             Classr   08690                                  youth
             oom,                                            groups
             Inc.
------------------------------------------------------------------------
Monetary    Depress  5                 $1,000    3/17/2014  DBSA NJ
             ion      Village                                Mutual Aid
             and      Court                                  Support
             Bipola   Lawrenc                                Group
             r        eville,                                Facilitator
             Suppor   NJ                                     Training
             t        08648
             Allian
             ce
------------------------------------------------------------------------
Monetary    Detroit  10                $5,000    8/25/2014  Managing
             Centra   Peterbo                                SPMI and
             l City   ro                                     Chronic
             Commun   Profess                                Disease
             ity      ional
             Mental   Buildin
             Health   g
             , Inc.   Detroit
                      , MI
                      48201
------------------------------------------------------------------------
Monetary    Didi     4760              $3,500     5/7/2014  Healthy
             Hirsch   South                                  Inglewood
             Mental   Sepulve                                Project
             Health   da
             Servic   Bouleva
             es       rd
                      Culver
                      City,
                      CA
                      90230
------------------------------------------------------------------------
Monetary    Dress    3131              $9,000   10/13/2014  Dress for
             for      Princet                                Success
             Succes   on                                     Mercer
             s        Pike,                                  County--Job
                      Buildin                                Readiness
                      g 4,                                   Program
                      Suite                                  Expansion
                      209                                    Project--To
                      Lawrenc                                ols to
                      eville,                                Succeed
                      NJ
                      08648
------------------------------------------------------------------------
Monetary    Eden     2                 $5,000   10/14/2014  2015 Eden
             Autism   Merwick                                Autism
             Servic   Road                                   Services
             es       Princet                                Princeton
             Founda   on, NJ                                 Lecture
             tion     08540                                  Series on
                                                             Autism
------------------------------------------------------------------------
Monetary    Elijah'  211                 $850     5/7/2014  General
             s        Livings                                Operating
             Promis   ton                                    Support
             e        Ave.
                      New
                      Brunswi
                      ck, NJ
                      08901
------------------------------------------------------------------------
Monetary    Emma     670               $3,500     7/1/2014  Mental
             Norton   North                                  Health
             Servic   Robert                                 Recovery
             es       Street                                 Skills
                      St.                                    Training
                      Paul,                                  and
                      MN                                     Medication
                      55101-                                 Support at
                      2523                                   Emma Norton
                                                             Residence
------------------------------------------------------------------------
Monetary    Enable,  13                $6,000    11/5/2014  Connect with
             Inc.     Roszel                                 Enable
                      Road,                                  program
                      Suite
                      B110
                      Princet
                      on, NJ
                      08540
------------------------------------------------------------------------
Monetary    Every    Fred              $8,500   11/17/2014  Every Child
             Child    Vereen,                                Valued
             Valued   Jr.                                    After
             A NJ     Communi                                School
             Nonpro   ty                                     Program
             fit      Center
             Corpor   175
             ation    Johnson
                      Avenue
                      Lawrenc
                      eville,
                      NJ
                      08648
------------------------------------------------------------------------
Monetary    Everybo  PO Box            $2,000   11/17/2014  Coming Up
             dy       3127                                   for AIRTM
             Loves    Princet
             Kenny    on, NJ
             Projec   08543
             t,
             Inc.
------------------------------------------------------------------------
Monetary    Faith    39                $1,000    9/22/2014  Responsible
             Christ   Somerse                                Fatherhood
             ian      t Drive                                Empowerment
             Counse   Willing                                Workshop
             ling     boro,
             Center   NJ
                      08046
------------------------------------------------------------------------
Monetary    Family   1931              $8,000    5/27/2014  Behavioral
             Guidan   Notting                                Healthcare
             ce       ham Way                                Services
             Center   Hamilto                                for the
             Corpor   n, NJ                                  Chronically
             ation    08619                                  Mentally
                                                             Ill
------------------------------------------------------------------------
Monetary    Family   1 AAA            $15,000   11/17/2014  Get FIT
             Resour   Dr.                                    Youth
             ce       Suite                                  program
             Networ   203
             k        Trenton
                      , NJ
                      08691
------------------------------------------------------------------------
Monetary    Family   1 AAA             $1,000     5/9/2014  Fundraising
             Resour   Drive                                  event
             ce       Suite                                  support to
             Networ   203                                    benefit
             k        Trenton                                general
                      , NJ                                   mission of
                      08691                                  organizatio
                                                             n
------------------------------------------------------------------------
Monetary    Family   4                 $7,500     6/6/2014  Emergency
             Servic   Corners                                Homeless
             e        tone                                   Shelter
             Associ   Drive                                  Community
             ation    Langhor                                Nurse
             of       ne, PA                                 Educator
             Bucks    19047
             County
------------------------------------------------------------------------
Monetary    Family   790 Park          $4,000    5/27/2014  STEPS to
             Servic   Avenue                                 Wellness
             e        Hunting                                Program
             League   ton, NY
             , Inc.   11743
------------------------------------------------------------------------
Monetary    Federat  Administ          $1,000     5/9/2014  The Big Nosh
             ion of   rative                                 Vocational
             Organi   Offices                                Services
             zation   One                                    Program
             s        Farming
                      dale
                      Road
                      Route
                      109
                      West
                      Babylon
                      , NY
                      11704
------------------------------------------------------------------------
Monetary    Forsyth  61                   $75    12/3/2014  Employee
             Humane   Miller                                 directed
             Societ   Street                                 donation in
             y        Winston-                               lieu of
                      Salem,                                 company
                      NC                                     holiday
                      21704                                  gift
------------------------------------------------------------------------
Monetary    Foundat  2381              $7,000   11/17/2014  The ``I'm
             ion of   Lawrenc                                still
             Morris   eville                                 here''
             Hall/    Road                                   approach to
             St.      Lawrenc                                managing
             Lawren   eville,                                challenging
             ce       NJ                                     behaviors
                      08648                                  in Grace
                                                             Garden.
------------------------------------------------------------------------
Monetary    Foundat  2381              $2,500   11/17/2014  Fundraising
             ion of   Lawrenc                                event
             Morris   eville                                 support to
             Hall/    Road                                   benefit
             St.      Lawrenc                                general
             Lawren   eville,                                mission of
             ce       NJ                                     organizatio
                      08648                                  n
------------------------------------------------------------------------
Monetary    Gateway  11901             $9,500     7/1/2014  Support for
             Homes,   Reedy                                  a Nurse
             Inc.     Branch                                 Practitione
                      Road                                   r to
                      Chester                                provide
                      field,                                 comprehensi
                      VA                                     ve
                      23838                                  personalize
                                                             d health
                                                             education
                                                             and
                                                             counseling
------------------------------------------------------------------------
Monetary    Georgia  246               $1,500    6/18/2014  Consumer
             Mental   Sycamor                                scholarship
             Health   e                                      s to attend
             Consum   STreet                                 the 23rd
             er       Suite                                  Annual
             Networ   160                                    Statewide
             k        Decatur                                Consumer
                      , GA                                   Conference,
                      30030                                  ``Year of
                                                             the Peer''
------------------------------------------------------------------------
Monetary    Girl     201               $2,000    12/3/2014  Robotics
             Scouts   Grove                                  Program
             Heart    Street
             of New   Westfie
             Jersey   ld, NJ
             , Inc.   07090
------------------------------------------------------------------------
Monetary    Good     38 Elm            $1,000   12/19/2014  Peer Support
             Grief,   Street                                 Program--Pr
             Inc.     Morrist                                inceton
                      own, NJ
                      07960
------------------------------------------------------------------------
Monetary    Grand    700 Lawn            $100    2/11/2014  Memorial
             View     Avenue                                 donation
             Health   Sellers
             Founda   ville,
             tion     PA
                      18960
------------------------------------------------------------------------
Monetary    Gulf     13228 N.            $100    5/27/2014  Memorial
             Ridge    Central                                donation
             Counci   Avenue
             l Boy    Tampa,
             Scouts   FL
             of       33612-
             Americ   3462
             a
------------------------------------------------------------------------
Monetary    Habitat  31 Oak            $4,000   11/17/2014  Women Build
             for      Avenue,                                 A Brush
             Humani   Suite                                  with
             ty of    100                                    Kindness
             Greate   Chalfon
             r        t, PA
             Bucks    18914
------------------------------------------------------------------------
Monetary    Habitat  6860                $800    8/15/2014  Costs
             for      Cortona                                associated
             Humani   Drive,                                 with 2014
             ty of    Suite A                                Janssen
             Southe   Goleta,                                Cares
             rn       CA                                     Volunteer
             Santa    93117                                  Activity
             Barbar
             a
------------------------------------------------------------------------
Monetary    Hamilto  1315              $9,500   12/12/2014  A.C.T.
             n Area   Whiteho                                (Actively
             YMCA     rse-                                   Changing
                      Mercerv                                Together)
                      ille                                   Program
                      Road
                      Hamilto
                      n, NJ
                      08619
------------------------------------------------------------------------
Monetary    Heart    78                $2,000   12/19/2014  HealthCare
             to       Ditmars                                Portfolio
             Hearts   Avenue                                 Program
             , Inc.   Lawrenc
                      eville,
                      NJ
                      08648
------------------------------------------------------------------------
Monetary    Heartla  4750 N.           $7,500    8/15/2014  Pathways
             nd       Sherida                                Home,
             Health   n Road                                 supportive
             Outrea   Chicago                                housing
             ch       , IL                                   program for
                      60640                                  those
                                                             living with
                                                             mental
                                                             health
                                                             issues
------------------------------------------------------------------------
Monetary    HiTops,  21                $7,000   11/17/2014  HiTOPS'
             Inc.     Wiggins                                Dating
                      Street                                 Violence
                      Princet                                Risk-
                      on, NJ                                 Reduction
                      08540                                  and
                                                             Prevention
                                                             Program
------------------------------------------------------------------------
Monetary    HomeFro  1880             $20,000   10/20/2014  24-Hour and
             nt       Princet                                Emergency
                      on                                     Childcare
                      Avenue                                 Center:
                      Lawrenc                                Providing
                      eville,                                Care
                      NJ                                     ``Around
                      08648                                  the Time
                                                             Clock''
------------------------------------------------------------------------
Monetary    HomeFro  1880             $10,000   10/27/2014  Huchet House
             nt       Princet
                      on
                      Avenue
                      Lawrenc
                      eville,
                      NJ
                      08648
------------------------------------------------------------------------
Monetary    Hopewel  35                $1,000    9/16/2014  Hopewell
             l        Princet                                Elementary
             Elemen   on Ave                                 Science
             tary     Hopewel                                Fair 2015
             School   l, NJ
             Parent   08525
             Teache
             r
             Organi
             zation
             , Inc.
------------------------------------------------------------------------
Monetary    Hopewel  PO Box            $3,500    6/12/2014  Scholarship
             l        553                                    for a
             Valley   Penning                                Hopewell
             Educat   ton, NJ                                Valley
             ion      08534                                  Regional
             Founda                                          School
             tion                                            District
                                                             graduating
                                                             student
                                                             ($1,000), I
                                                             Dream a
                                                             World: 15
                                                             Day Artist
                                                             Residency
                                                             ($2500)
------------------------------------------------------------------------
Monetary    Horizon  120 S.            $1,000     5/7/2014  Philly Has
             House,   30th                                   Talent
             Inc.     St.                                    outreach
                      Philade                                and
                      lphia,                                 awareness
                      PA                                     event
                      19104
------------------------------------------------------------------------
Monetary    Hunterd  1410              $2,500    9/22/2014  Fundraising
             on       Route                                  event
             County   22 West                                support to
             YMCA     Annanda                                benefit
                      le, NJ                                 general
                      08801                                  mission of
                                                             organizatio
                                                             n
------------------------------------------------------------------------
Monetary    Institu  PO Box            $3,500   10/14/2014  IWWWE
             te of    7869                                   Nursing
             Wonder   West                                   Experiences
             ful      Trenton                                hip Program
             Women    , NJ
             Workin   08628
             g for
             Empowe
             rment
------------------------------------------------------------------------
Monetary    Interfa  3635              $5,000    8/28/2014  Fundraising
             ith      Quakerb                                event
             Caregi   ridge                                  support to
             vers     Road                                   benefit
             Trento   Suite                                  general
             n,       16                                     mission of
             Inc.     Hamilto                                organizatio
                      n, NJ                                  n
                      08619
------------------------------------------------------------------------
Monetary    Interfa  3635             $15,000   10/14/2014  Neighbors
             ith      Quakerb                                Helping
             Caregi   ridge                                  Neighbors
             vers     Road                                   program to
             Trento   Suite                                  support
             n,       16                                     elderly and
             Inc.     Hamilto                                disabled in
                      n, NJ                                  Mercer
                      08619                                  County
------------------------------------------------------------------------
Monetary    Isles,   10 Wood           $9,000   11/17/2014  Trenton
             Inc.     Street                                 ReHEET
                      Trenton                                (Residentia
                      , NJ                                   l, Health,
                      08618                                  Energy, and
                                                             Environment
                                                             al
                                                             Treatment)
------------------------------------------------------------------------
Monetary    Jewish   707               $7,500    12/4/2014  Mercer
             Family   Alexand                                County
             and      er Road                                Caregiver
             Childr   Suite                                  Help Line
             en's     102                                    and
             Servic   Princet                                Caregiver
             e of     on, NJ                                 Services
             Greate   08540
             r
             Mercer
             County
------------------------------------------------------------------------
Monetary    Junior   4365              $7,800   12/10/2014  2015 J&J
             Achiev   Route 1                                Pharma Day
             ement    South                                  Program
             of New   2nd
             Jersey   Floor
                      Princet
                      on, NJ
                      08540
------------------------------------------------------------------------
Monetary    Karis    1361              $3,500     6/6/2014  Direct
             Commun   Detroit                                support of
             ity      St.                                    the Karis
                      Denver,                                Community
                      CO                                     Continuum
                      80206                                  of Care
                                                             Programs in
                                                             lieu of
                                                             event
                                                             sponsorship
------------------------------------------------------------------------
Monetary    Kidsbri  4556              $4,500    9/22/2014  Kidsbridge
             dge,     South                                  Anti-
             Inc.     Broad                                  Bullying
                      Street                                 Life Skills
                      2nd                                    Program for
                      Floor                                  At-Risk
                      Trenton                                Children in
                      , NJ                                   Trenton at
                      08620                                  the
                                                             Elementary
                                                             School
                                                             Level
------------------------------------------------------------------------
Monetary    Laguna   362              $12,000    5/27/2014  Diabetes
             Beach    Third                                  Program for
             Commun   Street                                 Disadvantag
             ity      Laguna                                 ed
             Clinic   Beach,                                 Individuals
                      CA
                      92651
------------------------------------------------------------------------
Monetary    Latin    669               $3,500   12/10/2014  Door to
             Americ   Chamber                                Health/
             an       s                                      Puerta de
             Legal    Street                                 Salud
             Defens   Suite B                                program
             e And    Trenton
             Educat   , NJ
             ional    08611
             Fund,
             Inc.
------------------------------------------------------------------------
Monetary    Lawrenc  PO Box            $2,710    10/1/2014  Engaging
             e        6531 17                                Budding
             Townsh   Philips                                Engineers
             ip       Ave.                                   at
             Educat   Lawrenc                                Lawrencevil
             ion      eville,                                le
             Founda   NJ                                     Elementary
             tion,    08648                                  School:
             Inc.                                            enhancing
                                                             the third
                                                             grade STEM
                                                             curriculum.
------------------------------------------------------------------------
Monetary    Leyden   10001             $5,000    7/18/2014  Health Home
             Family   Grand                                  and
             Servic   Avenue                                 Integrated
             e and    Frankli                                Care =
             Mental   n Park,                                Innovation
             Health   IL                                     program
             Center   60131
------------------------------------------------------------------------
Monetary    Liberta  5245              $6,500    12/4/2014  Psychiatric
             e,       Bensale                                Services
             Inc.     m                                      for Women
                      Bouleva                                Recovering
                      rd                                     from
                      Bensale                                Substance
                      m, PA                                  Use
                      19020                                  Disorders
------------------------------------------------------------------------
Monetary    LifeTie  LifeTies          $5,150   11/17/2014  The
             s,       , Inc.                                 Transgender
             Inc.     2205                                   Youth
                      Penning                                Health
                      ton                                    Services
                      Road                                   Project:
                      Ewing,                                 Staff
                      NJ                                     Training
                      08638                                  and Mentor
                                                             Program
------------------------------------------------------------------------
Monetary    Literac  55                $2,500   12/18/2014  Early
             y and    Primros                                Childhood:
             Life,    e                                      Building
             Inc.     Circle                                 Blocks for
                      Princet                                the Future
                      on, NJ
                      08540
------------------------------------------------------------------------
Monetary    Literac  121               $5,000    12/3/2014  Adult
             y New    Chestnu                                Literacy
             Jersey   t                                      Program in
             , Inc.   Street                                 Mercer
                      Suite                                  County
                      203
                      Roselle
                      , NJ
                      07203
------------------------------------------------------------------------
Monetary    Literac  120               $4,000   11/17/2014  Literate
             y        Findern                                Moms,
             Volunt   e Ave--                                Stable
             eers     Box 7                                  Futures
             of       Bridgew                                program
             Somers   ater,
             et       NJ
             County   08807
------------------------------------------------------------------------
Monetary    Main     8                 $2,500     7/1/2014  Accessible
             Street   Marcell                                Care for
             Counse   a                                      Schizoaffec
             ling     Avenue                                 tive
             Center   West                                   Disorder
                      Orange,
                      NJ
                      07052
------------------------------------------------------------------------
Monetary    Mary's   15                   $75    3/17/2014  Employee
             Place    Broadwa                                directed
             By The   y Ocean                                donation in
             Sea      Grove,                                 lieu of
                      NJ                                     company
                      07756                                  holiday
                                                             gift
------------------------------------------------------------------------
Monetary    Massach  130               $2,500     6/6/2014  Peer Support
             usetts   Bowdoin                                Whole
             Associ   Street                                 Health
             ation    Boston,                                Resiliency
             for      MA                                     Program
             Mental   02108
             Health
             Inc.
------------------------------------------------------------------------
Monetary    McCarte  91                $9,500   11/17/2014  OnStage
             r        Univers                                Seniors: A
             Theatr   ity                                    Community
             e        Place                                  Project of
             Center   Princet                                McCarter
                      on, NJ                                 Theatre
                      08450
------------------------------------------------------------------------
Monetary    Meals    5 Walter            $300     8/4/2014  Cost
             On       Foran                                  associated
             Wheels   Bouleva                                with 2014
             in       rd                                     Janssen
             Hunter   Suite                                  Cares
             don,     2006                                   volunteer
             Inc.     Fleming                                activity
                      ton, NJ
                      08822
------------------------------------------------------------------------
Monetary    Meals    180              $15,000   10/22/2014  Meals-on-
             on       Ewingvi                                Wheels
             Wheels   lle                                    Program
             of       Road
             Trento   Ewing,
             n        NJ
             Ewing    08638
------------------------------------------------------------------------
Monetary    Mental   1431              $1,000     6/6/2014  2014 Mental
             Health   North                                  Health
             Americ   Delawar                                Symposium
             a        e                                      and Annual
                      Street                                 Meeting
                      Indiana
                      polis,
                      IN
                      46202
------------------------------------------------------------------------
Monetary    Mental   2000             $90,000   12/10/2014  Building
             Health   North                                  Skills of
             Americ   Beaureg                                Caregivers
             a        ard                                    to Assist
                      Street                                 People
                      6th                                    Living with
                      Floor                                  Schizophren
                      Alexand                                ia through
                      ria, VA                                Social Self-
                      22311                                  Directed
                                                             Care
------------------------------------------------------------------------
Monetary    Mental   70 E.             $1,500    8/28/2014  Mental
             Health   Lake                                   Health and
             Americ   Street                                 Wellness
             a        Suite                                  Fair/
                      900                                    Chicago
                      Chicago                                Area
                      , IL                                   Resource
                      60601                                  Guide
------------------------------------------------------------------------
Monetary    Mental   2211             $15,000     8/1/2014  School
             Health   Norfolk                                Behavioral
             Americ   Suite                                  Health
             a of     810                                    Initiative
             Greate   Houston
             r        , TX
             Housto   77098
             n
------------------------------------------------------------------------
Monetary    Mental   1385 S.           $2,500     7/1/2014  Pro Bono
             Health   Colorad                                Counseling
             Americ   o                                      and
             a of     Bouleva                                Referral
             Colora   rd                                     Program
             do       Suite
                      610
                      Denver,
                      CO
                      80222
------------------------------------------------------------------------
Monetary    Mental   2323 W.          $10,000    7/11/2014  Get
             Health   Fifth                                  Connected
             Americ   Avenue                                 Wellness
             a of     Suite                                  program
             Frankl   160
             in       Columbu
             County   s, OH
                      43204
------------------------------------------------------------------------
Monetary    Mental   100               $5,000     7/1/2014  What is
             Health   Edgewoo                                Schizophren
             Americ   d                                      ia?
             a of     Avenue                                 Educational
             Georgi   Suite                                  Forum
             a        502
                      Atlanta
                      , GA
                      30303
------------------------------------------------------------------------
Monetary    Mental   1210 San          $2,500     7/1/2014  Mental
             Health   Antonio                                Health
             Americ   Street                                 Education
             a of     Suite                                  and
             Texas    200                                    Advocacy
                      Austin,                                Campaign
                      TX
                      78757
------------------------------------------------------------------------
Monetary    Mental   475               $2,500    5/27/2014  Mental
             Health   Clevela                                Health
             Associ   nd                                     Education
             ation    Avenue                                 for Support
                      N Suite                                Systems
                      222
                      Saint
                      Paul,
                      MN
                      55104
------------------------------------------------------------------------
Monetary    Mental   870               $7,500     8/1/2014  Reducing the
             Health   Market                                 Stigma and
             Associ   Street                                 Discriminat
             ation    Suite                                  ion of
                      928 San                                Mental
                      Francis                                Illness
                      co, CA                                 within
                      94102                                  Multi-
                                                             cultural
                                                             Communities
------------------------------------------------------------------------
Monetary    Mental   100 West          $1,500     7/1/2014  13th Annual
             Health   10th                                   Community
             Associ   Street                                 Mental
             ation    Suite                                  Health
             in       600                                    Conference-
             Delawa   Wilming                                -Back to
             re       ton, DE                                Basics:
                      19801                                  Mind, Body
                                                             and Spirit
------------------------------------------------------------------------
Monetary    Mental   100 West          $1,000    8/15/2014  Bronze
             Health   10th                                   sponsor
             Associ   Street                                 2014 E-
             ation    Suite                                  Racing the
             in       600                                    Blues 5K
             Delawa   Wilming                                Run/Walk
             re       ton, DE                                10K Run
                      19801
------------------------------------------------------------------------
Monetary    Mental   330 S.            $5,000     8/1/2014  Schizophreni
             Health   Greene                                 a and
             Associ   St,                                    Schizo-
             ation    Suite B-                               Affective
             In       12                                     Supportive
             Greens   Greensb                                Services
             boro,    oro, NC
             Inc.     27401
------------------------------------------------------------------------
Monetary    Mental   88                $1,000    8/28/2014  Silver
             Health   Pompton                                Sponsor 7th
             Associ   Ave.                                   Annual Walk
             ation    Verona,                                for
             in New   NJ                                     Wellness
             Jersey   07044                                  and
                                                             Recovery
------------------------------------------------------------------------
Monetary    Mental   617               $2,500     6/5/2014  Support
             Health   Garden                                 Mental
             Associ   Street                                 Wellness
             ation    Santa                                  Center
             in       Barbara
             Santa    , CA
             Barbar   93101
             a
             County
------------------------------------------------------------------------
Monetary    Mental   3701              $8,000     8/1/2014  Mental
             Health   Latrobe                                Health
             Associ   Drive,                                 First Aid
             ation    Suite                                  Training
             of       140                                    for
             Centra   Charlot                                Mecklenburg
             l        te, NC                                 County
             Caroli   28211                                  Sheriff's
             nas                                             Office
             Inc
------------------------------------------------------------------------
Monetary    Mental   1301             $10,000    9/17/2014  Health Care
             Health   York                                   Reform
             Associ   Road                                   Parity
             ation    Suite                                  Initiative
             of       505
             Maryla   Lutherv
             nd,      ille,
             Inc.     MD
                      21093
------------------------------------------------------------------------
Monetary    Mental   2335              $1,000     7/1/2014  Open Doors
             Health   Tamiami                                Open Minds--
             Associ   Trail                                  Cultural
             ation    North                                  Competency
             of       (Ninth                                 Educational
             Southw   Street)                                Program
             estern   Suite                                  Promoting
             Florid   404                                    Wellness
             a        Naples,                                and
                      FL                                     Recovery
                      34103                                  Through
                                                             Inclusion
------------------------------------------------------------------------
Monetary    Mental   580               $1,000    2/13/2014  Supporting
             Health   White                                  sponsor
             Associ   Plains                                 2014 MHA on
             ation    Road                                   the Move:
             of       Tarryto                                Run/Walk
             Westch   wn, NY
             ester    10591
------------------------------------------------------------------------
Monetary    Mental   1870              $1,000    7/24/2014  Copper
             Health   South                                  sponsor for
             Associ   Boulder                                the 20th
             ation    Avenue                                 Annual
             Oklaho   Tulsa,                                 Zarrow
             ma       OK                                     Mental
                      74119-                                 Health
                      5234                                   Symposium,
                                                             ``All
                                                             Things
                                                             Prevention'
                                                             '
------------------------------------------------------------------------
Monetary    Mental   555N.             $4,000    8/15/2014  MHA Housing
             Health   Woodlaw                                Initiative:
             Associ   n,                                     Ensuring
             ation    Suite                                  Housing for
             Reside   3105                                   Our Most
             ntial    Wichita                                Vulnerable
             Care     , KS                                   Populations
             Inc.     67208
------------------------------------------------------------------------
Monetary    Mental   4141 E.           $7,500     7/1/2014  Enhancement
             Health   Dickens                                of The
             Center   on                                     Downstairs
             of       Place                                  program
             Denver   Denver,
                      CO
                      80222
------------------------------------------------------------------------
Monetary    Mental   3809             $10,000    6/24/2014  Outreach and
             Illnes   Rosewoo                                Behavioral
             s        d Dr.                                  Healthcare
             Recove   P.O.                                   for
             ry       Box                                    Homeless
             Center   4246                                   Individuals
             , Inc.   Columbi                                with Mental
                      a, SC                                  Illness
                      29240
------------------------------------------------------------------------
Monetary    Mercer   3150              $7,500    12/4/2014  Integrating
             Allian   Brunswi                                healthcare
             ce to    ck Pike                                access into
             End      Lawrenc                                operation
             Homele   eville,                                of the
             ssness   NJ                                     Mercer
                      08648-                                 County
                      2420                                   Service
                                                             Access
                                                             Center for
                                                             Homeless
                                                             Individuals
------------------------------------------------------------------------
Monetary    Mercer   PO Box            $3,950   11/17/2014  Z.O.M.B.I.E.
             County   17202                                  : Zooming
             Commun   Trenton                                in On
             ity      , NJ                                   Making
             Colleg   08690                                  Biology
             e                                               Interactive
             Founda                                          and
             tion                                            Engaging--(
                                                             Peer Tutor
                                                             support)
------------------------------------------------------------------------
Monetary    Mercer   Growth            $7,500    8/11/2014  Data Through
             Region   Partner                                Action:
             al       ship of                                Education
             Econom   Central                                and Tourism
             ic       Jersey,                                Initiatives
             Develo   Inc. 1A                                Throughout
             pment    Quakerb                                Central New
             Founda   ridge                                  Jersey
             tion,    Plaza
             Inc.     Drive,
                      Suite 2
                      Mercerv
                      ile, NJ
                      08619
------------------------------------------------------------------------
Monetary    Mercer   151              $20,000    9/22/2014  Food Bank--
             Street   Mercer                                 Healthy
             Friend   Street                                 Choices
             s        Trenton
                      , NJ
                      08611
------------------------------------------------------------------------
Monetary    Merrima  60                  $800    8/26/2014  Costs
             ck       Island                                 associated
             Valley   Street                                 with 2014
             Habita   2nd                                    Janssen
             t for    Floor                                  Cares
             Humani   East                                   volunteer
             ty       Lawrenc                                activity
                      e, MA
                      01840
------------------------------------------------------------------------
Monetary    Metropo  1 North           $1,500     8/4/2014  Adult Mental
             litan    Dearbor                                Health
             Family   n                                      Wellness
             Servic   Chicago                                Initiative
             es       , IL
                      60602
------------------------------------------------------------------------
Monetary    Michael  1115                $100   12/19/2014  Memorial
             Stern    Broadwa                                Donation
             Parkin   y,
             son's    Suite
             Resear   1200
             ch       New
             Founda   York,
             tion     NY
                      10010
------------------------------------------------------------------------
Monetary    Middle   P.O. Box         $15,000   10/14/2014  Outreach
             Earth    8045                                   Program and
                      520                                    Community
                      North                                  Youth
                      Bridge                                 Centers
                      Street
                      Bridgew
                      ater,
                      NJ
                      08807
------------------------------------------------------------------------
Monetary    Midland  60                $7,500    9/22/2014  Midland
             Adult    Industr                                Helping
             Servic   ial                                    Hands
             es,      Parkway                                Employment
             Inc.     PO Box                                 Training
                      5026                                   Program
                      North
                      Branch,
                      NJ
                      08876
------------------------------------------------------------------------
Monetary    Millhil  101              $15,000    11/5/2014  Trenton
             l        Oakland                                PEERS--Teen
             Child    Street                                 Education
             and      Trenton                                and
             Family   , NJ                                   Empowerment
                      08618                                  Program
------------------------------------------------------------------------
Monetary    Millhil  101-A               $300     8/4/2014  Cost
             l        Oakland                                associated
             Founda   Street                                 with 2014
             tion,    Trenton                                Janssen
             Inc.     , NJ                                   Cares
                      08618                                  volunteer
                                                             activity
------------------------------------------------------------------------
Monetary    Minding  2083              $5,000    3/17/2014  2014 Minding
             our      Lawrenc                                Our
             Busine   eville                                 Business
             ss,      Rd                                     Summer
             Inc.     Lawrenc                                Program:
                      eville,                                Bridge to
                      NJ                                     the Future
                      08648                                  for Mercer
                                                             County
                                                             Youth
------------------------------------------------------------------------
Monetary    Morven   55                $5,000   10/14/2014  Morven
             Museum   Stockto                                Museum and
             and      n                                      Garden
             Garden   Street                                 Summer
                      Princet                                Internship
                      on, NJ                                 Program for
                      08540                                  Isles of
                                                             Trenton
                                                             Youths
------------------------------------------------------------------------
Monetary    Mount    73 North         $12,500    9/22/2014  Mount Carmel
             Carmel   Clinton                                Guild Home
             Guild    Avenue                                 Health
                      Trenton                                Nursing
                      , NJ                                   Program
                      08609
------------------------------------------------------------------------
Monetary    NAMI--C  1904              $1,000    5/27/2014  Consumer,
             VA       Byrd                                   Public, and
             Centra   Ave                                    Provider
             l        Richmon                                Education:
             Virgin   d, VA                                  Peer to
             ias      23230                                  Peer and In
             Voice                                           Our Own
             On                                              Voice
             Mental                                          Programs
             Illnes
             s
------------------------------------------------------------------------
Monetary    NAMI     1012              $1,000    2/13/2014  Bronze
             Arkans   Autumn                                 sponsor
             as       Rd                                     2014
                      Suite 1                                Arkansas
                      Little                                 NAMIWalk
                      Rock,
                      AR
                      72211
------------------------------------------------------------------------
Monetary    NAMI     2400              $1,000     5/9/2014  Bronze
             Delawa   West                                   sponsor
             re       4th St.                                12th Annual
                      Wilming                                NAMI
                      ton, DE                                Delaware
                      19805                                  Walk
------------------------------------------------------------------------
Monetary    NAMI     P.O. Box          $1,000    7/18/2014  Purchase of
             Lansin   26101                                  books for
             g,       Lansing                                family
             Inc.     , MI                                   education,
                      48909                                  communicati
                                                             on
                                                             enhancement
                                                             and support
------------------------------------------------------------------------
Monetary    NAMI     3371              $2,500    1/14/2014  Silver
             Mercer   Brunswi                                sponsor
             NJ       ck Pike                                NAMI Mercer
                      Suite                                  Walk 2014
                      124
                      Lawrenc
                      eville,
                      NJ
                      08648
------------------------------------------------------------------------
Monetary    NAMI     3371              $9,500     6/6/2014  Education
             Mercer   Brunswi                                and Support
             NJ       ck Pike                                Programs
                      Suite
                      124
                      Lawrenc
                      eville,
                      NJ
                      08648
------------------------------------------------------------------------
Monetary    NAMI     3371              $2,500   12/10/2014  Silver
             Mercer   Brunswi                                sponsor
             NJ       ck Pike                                2015 NAMI
                      Suite                                  Mercer Walk
                      124
                      Lawrenc
                      eville,
                      NJ
                      08648
------------------------------------------------------------------------
Monetary    NAMI of  2100              $5,000     7/1/2014  Educational
             DuPage   Manches                                and
             County   ter                                    supportive
             Illino   Road                                   services
             is       Buildin                                programs to
                      g B                                    include
                      Suite                                  community
                      925                                    outreach,
                      Wheaton                                school
                      , IL                                   connections
                      60187                                  , hospital
                                                             education,
                                                             educational
                                                             courses,
                                                             NAMI
                                                             Connection,
                                                             MICAP,
                                                             Family
                                                             Support
                                                             Group and
                                                             other
                                                             resources
------------------------------------------------------------------------
Monetary    NAMI of  One                 $500    8/15/2014  Bronze
             Lake     Victori                                sponsor
             County   a Sq.,                                 2014 NAMI
                      Ste.                                   Lake
                      260                                    County's
                      Painesv                                Strides for
                      ille,                                  Awareness
                      OH                                     Walk
                      44077
------------------------------------------------------------------------
Monetary    NAMI of  100 West          $1,000    3/17/2014  Bronze
             PA       Main                                   sponsor
             Montgo   Street                                 2014
             mery     Suite                                  Greater
             County   204                                    Philadelphi
                      Lansdal                                a NAMIWalk
                      e, PA
                      19446
------------------------------------------------------------------------
Monetary    NAMI     1750              $1,000     5/9/2014  Bronze
             St.      South                                  sponsor
             Louis    Brentwo                                2014
                      od                                     NAMIWalks
                      Blvd.,
                      Suite
                      511 St.
                      Louis,
                      MO
                      63144
------------------------------------------------------------------------
Monetary    NAMI     PO Box            $1,000     3/6/2014  Bronze
             Summit   462                                    sponsor
             County   Cuyahog                                NAMIWalks
                      a                                      2014
                      Falls,
                      OH
                      44321
------------------------------------------------------------------------
Monetary    NAMI     5251              $1,000    2/13/2014  Bronze
             Ventur   Verdugo                                sponsor
             a        Road,                                  NAMIWalk
             County   Suite K                                Ventura
                      PO Box                                 County 2014
                      1613
                      Camaril
                      lo, CA
                      93011
------------------------------------------------------------------------
Monetary    NAMI     217               $1,000    5/27/2014  Bronze
             Waukes   Wiscons                                sponsor
             ha       in Ave                                 2014
                      Suite                                  NAMIWalks
                      300                                    in Waukesha
                      Waukesh
                      a, WI
                      53186
------------------------------------------------------------------------
Monetary    Nationa  90 Park           $2,500   10/23/2014  26th Annual
             l        Avenue                                 New York
             Allian   16                                     Mental
             ce for   Floor                                  Health
             Resear   New                                    Research
             ch on    York,                                  Symposium
             Schizo   NY
             phreni   10016
             a and
             Depres
             sion
------------------------------------------------------------------------
Monetary    Nationa  1 Bangor          $1,000    5/16/2014  Supporter
             l        Street                                 sponsor
             Allian   Augusta                                2014 NAMI
             ce for   , ME                                   Maine Walk
             the      04330                                  for Mental
             Mental                                          Health
             ly Ill                                          Awareness
------------------------------------------------------------------------
Monetary    Nationa  10630             $1,000    9/16/2014  Silver
             l        Little                                 sponsor
             Allian   Patuxen                                NAMI
             ce for   t                                      Maryland
             the      Parkway                                2014 Annual
             Mental   Columbi                                Education
             ly Ill   a, MD                                  Conference
                      21044
------------------------------------------------------------------------
Monetary    Nationa  1225             $10,000     5/9/2014  NAMI Ohio's
             l        Dublin                                 Medication
             Allian   Road;                                  Access
             ce for   Ste.                                   Initiative
             the      125
             Mental   Columbu
             ly Ill   s, OH
                      43215
------------------------------------------------------------------------
Monetary    Nationa  1536              $7,500     7/1/2014  ``Ending the
             l        West                                   Silence''
             Allian   Chicago                                training
             ce for   Avenue                                 for
             the      Chicago                                students
             Mental   , IL                                   regarding
             ly Ill   60622                                  mental
                                                             illness and
                                                             brain
                                                             disorders
                                                             ($6000) and
                                                             Special and
                                                             Restorative
                                                             Programming
                                                             for
                                                             individuals
                                                             living with
                                                             Mental
                                                             Illness
                                                             ($1500)
------------------------------------------------------------------------
Monetary    Nationa  1562              $1,000    3/17/2014  Bronze
             l        Route                                  sponsor
             Allian   130                                    2014
             ce for   North                                  NAMIWalks
             the      Brunswi                                New Jersey:
             Mental   ck, NJ                                 Step
             ly Ill   08902                                  Forward for
                                                             Our Heroes
------------------------------------------------------------------------
Monetary    Nationa  1562              $2,500     7/1/2014  2014
             l        Route                                  Conference:
             Allian   130                                    Expanding
             ce for   North                                  Horizons
             the      Brunswi
             Mental   ck, NJ
             ly Ill   08902
------------------------------------------------------------------------
Monetary    Nationa  237               $1,000    12/3/2014  Bronze
             l        Fernwoo                                sponsor
             Allian   d Blvd                                 2015
             ce for   Suite                                  NAMIWALKS,
             the      101                                    Changing
             Mental   Fern                                   minds one
             ly Ill   Park,                                  step at a
                      FL                                     time.
                      32730
------------------------------------------------------------------------
Monetary    Nationa  309 West          $1,000    3/17/2014  Bronze
             l        Millbro                                sponsor
             Allian   ok Road                                2014
             ce for   Suite                                  NAMIWalks
             the      121
             Mental   Raleigh
             ly Ill   , NC
                      27609
------------------------------------------------------------------------
Monetary    Nationa  3250              $1,000     3/6/2014  Bronze
             l        Wilshir                                sponsor
             Allian   e Blvd                                 2014
             ce for   Ste                                    NAMIWalks
             the      1501                                   Los Angeles
             Mental   Los                                    County
             ly Ill   Angeles
                      , CA
                      90010
------------------------------------------------------------------------
Monetary    Nationa  3440              $1,000     7/1/2014  Bronze
             l        Viking                                 sponsor
             Allian   Drive,                                 Northern
             ce for   Suite                                  California
             the      104A                                   NAMI Walk
             Mental   Sacrame                                2015
             ly Ill   nto, CA
                      95827
------------------------------------------------------------------------
Monetary    Nationa  3803 N.          $50,000   12/10/2014  Crisis
             l        Fairfax                                Interventio
             Allian   Drive                                  n Team
             ce for   Suite                                  Technical
             the      100                                    Assistance
             Mental   Arlingt                                and
             ly Ill   on, VA                                 Statewide
                      22203                                  Expansion
------------------------------------------------------------------------
Monetary    Nationa  3803 N.          $35,000   12/10/2014  Multicultura
             l        Fairfax                                l Action
             Allian   Drive                                  Center
             ce for   Suite
             the      100
             Mental   Arlingt
             ly Ill   on, VA
                      22203
------------------------------------------------------------------------
Monetary    Nationa  3803 N.          $40,000   12/10/2014  NAMI Basics
             l        Fairfax                                Education
             Allian   Drive                                  Program
             ce for   Suite
             the      100
             Mental   Arlingt
             ly Ill   on, VA
                      22203
------------------------------------------------------------------------
Monetary    Nationa  498               $9,500    8/14/2014  NAMI
             l        Georget                                Lexington
             Allian   own                                    Advocacy,
             ce for   Street                                 Education,
             the      Suite                                  Outreach
             Mental   201                                    and Support
             ly Ill   Lexingt                                ($8,500),
                      on, KY                                 bronze
                      40508                                  sponsor
                                                             2014 Walk
                                                             ($1,000)
------------------------------------------------------------------------
Monetary    Nationa  576               $1,000    1/15/2014  Bronze
             l        Farming                                sponsor
             Allian   ton                                    2014
             ce for   Avenue                                 NAMIWalks
             the      Hartfor
             Mental   d, CT
             ly Ill   06105
------------------------------------------------------------------------
Monetary    Nationa  800               $1,000     5/7/2014  Bronze
             l        Transfe                                sponsor
             Allian   r Road                                 NAMIWalks
             ce for   Suite                                  2014
             the      31
             Mental   Saint
             ly Ill   Paul,
                      MN
                      55114
------------------------------------------------------------------------
Monetary    Nationa  800               $1,000     7/1/2014  NAMI
             l        Transfe                                Connections
             Allian   r Road                                 Training
             ce for   Suite
             the      31
             Mental   Saint
             ly Ill   Paul,
                      MN
                      55114
------------------------------------------------------------------------
Monetary    Nationa  99 Pine           $3,000    8/28/2014  2014 NAMI-
             l        St.                                    NYS
             Allian   Suite                                  Education
             ce for   302                                    Conference-
             the      Albany,                                United We
             Mental   NY                                     Stand:
             ly Ill   12207                                  Shaping our
                                                             Future.
------------------------------------------------------------------------
Monetary    Nationa  Kentucky          $1,000     7/1/2014  Community
             l        Affilia                                Sponsor
             Allian   te c/o                                 2014 Annual
             ce for   Somerse                                Conference,
             the      t                                      ``Advocatin
             Mental   Communi                                g for
             ly Ill   ty                                     Change
                      College                                Together''
                      808
                      Montice
                      llo
                      Street
                      Somerse
                      t, KY
                      42501
------------------------------------------------------------------------
Monetary    Nationa  PO Box            $1,000    7/24/2014  Family-to-
             l        22697                                  Family and
             Allian   2601                                   Peer-to-
             ce for   Cold                                   Peer
             the      Spring                                 Education
             Mental   Road                                   programs
             ly Ill   Indiana
                      polis,
                      IN
                      46222-
                      0697
------------------------------------------------------------------------
Monetary    Nationa  PO Box            $1,000   10/23/2014  Bronze
             l        66270                                  sponsor
             Allian   Houston                                2015
             ce for   , TX                                   NAMIWalks
             the      77274                                  Greater
             Mental                                          Houston
             ly Ill
------------------------------------------------------------------------
Monetary    Nationa  PO Box            $1,000     7/1/2014  Bronze
             l        8260                                   sponsor
             Allian   Richmon                                2014
             ce for   d, VA                                  NAMIWalks
             the      23218                                  Virginia
             Mental
             ly Ill
------------------------------------------------------------------------
Monetary    Nationa  Scott             $1,000    5/16/2014  Bronze
             l        County                                 sponsor
             Allian   1706                                   2014
             ce for   Brady                                  NAMIWalk
             the      Street                                 Greater
             Mental   Suite                                  Mississippi
             ly Ill   200                                    Valley
                      Davenpo
                      rt, IA
                      52803
------------------------------------------------------------------------
Monetary    Nationa  The               $1,000    3/17/2014  Bronze
             l        Schraff                                sponsor
             Allian   t's                                    2014
             ce for   Center                                 NAMIWalks
             the      529                                    Massachuset
             Mental   Main                                   ts
             ly Ill   Street
                      Suite
                      1M17
                      Boston,
                      MA
                      02129
------------------------------------------------------------------------
Monetary    Nationa  2012              $1,000     7/1/2014  Mental
             l        West                                   Illness
             Allian   25th                                   Peer
             ce for   Street                                 Support and
             the      6th                                    Education
             Mental   Floor                                  programs
             ly       Clevela
             Ill--G   nd, OH
             reater   44113
             Clevel
             and
------------------------------------------------------------------------
Monetary    Nationa  2012              $1,000    8/12/2014  Bronze
             l        West                                   sponsor
             Allian   25th                                   2014
             ce for   Street                                 NAMIWalks
             the      6th                                    for the
             Mental   Floor                                  Mind of
             ly       Clevela                                America
             Ill--G   nd, OH                                 Greater
             reater   44113                                  Cleveland
             Clevel
             and
------------------------------------------------------------------------
Monetary    Nationa  5911              $1,000    8/12/2014  Bronze
             l        Meredit                                sponsor
             Allian   h Drive                                2014 NAMI
             ce for   Suite E                                IOWA
             the      Des                                    NAMIWalk
             Mental   Moines,
             ly       IA
             Ill--I   50322-
             owa      1903
------------------------------------------------------------------------
Monetary    Nationa  2753              $1,000    1/15/2014  Bronze
             l        West                                   sponsor
             Allian   Central                                2014
             ce for   Avenue                                 NAMIWalk
             the      Toledo,
             Mental   OH
             ly Ill   43606
             of
             Greate
             r
             Toledo
------------------------------------------------------------------------
Monetary    Nationa  505               $1,000    2/13/2014  Bronze
             l        Eighth                                 sponsor
             Allian   Avenue                                 NAMIWalks
             ce for   Suite                                  NYC 2014
             the      1103                                   Walk/Run
             Mental   New
             ly Ill   York,
             of New   NY
             York     10018
             City
------------------------------------------------------------------------
Monetary    Nationa  1981              $1,000    11/5/2014  Bronze
             l        Marcus                                 sponsor
             Allian   Ave,                                   2015 Long
             ce for   C117                                   Island/
             the      Lake                                   Queens
             Mental   Success                                NAMIWalk
             ly Ill   , NY                                   for Mental
             Queens/  11042                                  Health
             Nassau
------------------------------------------------------------------------
Monetary    Nationa  of                $1,000    8/12/2014  Bronze
             l        Butler                                 sponsor
             Allian   County                                 2014
             ce on    5963                                   National
             Mental   Boymel                                 Alliance on
             Illnes   Drive                                  Mental
             s        Fairfie                                Illness of
                      ld, OH                                 Butler
                      45014                                  County
                                                             NAMIWalks
------------------------------------------------------------------------
Monetary    Nationa  1150              $3,500    5/15/2014  Peer PALS
             l        South                                  program
             Allian   Bascom
             ce on    Ave.,
             Mental   Ste 24,
             Illnes   San
             s        Jose,
             Santa    CA
             Clara    95128
             County
------------------------------------------------------------------------
Monetary    Nationa  P O Box           $6,000    5/16/2014  27 Annual
             l Art    350891                                 National
             Exhibi   Miami                                  Art
             tions    Fl                                     Exhibition
             of the   33135                                  by the
             Mental                                          Mentally
             ly                                              Ill
             Ill,
             Inc
------------------------------------------------------------------------
Monetary    Nationa  110 N.           $30,000   11/17/2014  STOP THE
             l        Washing                                CLOT,
             Blood    ton                                    SPREAD THE
             Clot     Street                                 WORD VTE
             Allian   Suite                                  Awareness
             ce       328                                    and
                      Rockvil                                Advocacy
                      le, MD                                 Initiative
                      20850                                  : Patient
                                                             Toolkit
                                                             ($15,000),
                                                             and
                                                             Specialty
                                                             Magazines
                                                             ($15,000)
------------------------------------------------------------------------
Monetary    Nationa  110               $7,500    3/17/2014  Education
             l        North                                  briefing,
             Blood    Washing                                ``So You
             Clot     ton                                    Think You
             Allian   Street                                 Can't Get A
             ce       Suite                                  Blood Clot?
                      328 B                                  Think
                      Rockvil                                Again!''
                      le, MD
                      20850
------------------------------------------------------------------------
Monetary    Nationa  1701 K           $20,000   12/10/2014  Prescription
             l        Street                                 Drug Abuse
             Counci   NW,                                    and Pain
             l for    Suite                                  Management
             Behavi   400                                    Initiative
             oral     Washing
             Health   ton, DC
                      20006
------------------------------------------------------------------------
Monetary    Nationa  1701 K           $60,000   12/10/2014  Same Day
             l        Street                                 Access
             Counci   NW,                                    Initiative
             l for    Suite
             Behavi   400
             oral     Washing
             Health   ton, DC
                      20006
------------------------------------------------------------------------
Monetary    Nationa  1701 K           $35,000   12/10/2014  Early Onset
             l        Street                                 Psychosis
             Counci   NW,                                    Initiative
             l for    Suite
             Behavi   400
             oral     Washing
             Health   ton, DC
                      20006
------------------------------------------------------------------------
Monetary    Nationa  1701 K           $50,000   12/10/2014  Health
             l        Street                                 Justice
             Counci   NW,                                    Learning
             l for    Suite                                  Initiative
             Behavi   400
             oral     Washing
             Health   ton, DC
                      20006
------------------------------------------------------------------------
Monetary    Nationa  1701 K           $75,000   12/10/2014  2015 Policy
             l        Street                                 Action
             Counci   NW,                                    Center
             l for    Suite
             Behavi   400
             oral     Washing
             Health   ton, DC
                      20006
------------------------------------------------------------------------
Monetary    Nationa  1701 K           $30,000   12/10/2014  Leadership
             l        Street                                 Development
             Counci   NW,                                    Initiatives
             l for    Suite
             Behavi   400
             oral     Washing
             Health   ton, DC
                      20006
------------------------------------------------------------------------
Monetary    Nationa  949 W.           $16,500    12/3/2014  Academic
             l        State                                  Creative
             Junior   Street                                 Engagement
             Tennis   Trenton                                Program
             and      , NJ                                   ($6,500.00)
             Learni   08618                                  ,
             ng of                                           Benefactor
             Trento                                          sponsor
             n                                               2015 Annual
                                                             Gala
                                                             ($10,000.00
                                                             )
------------------------------------------------------------------------
Monetary    Nationa  9707 E           $10,000   11/19/2014  Patient
             l        Easter                                 Navigator
             Stroke   Lane,                                  Program /
             Associ   Suite B                                Stroke
             ation    Centenn                                Recovery
                      ial, CO                                Navigator
                      80112
------------------------------------------------------------------------
Monetary    Nationa  9707 E           $62,290   11/19/2014  Web-based
             l        Easter                                 health
             Stroke   Lane,                                  game,
             Associ   Suite B                                ``Stroke
             ation    Centenn                                and
                      ial, CO                                Nonvalvular
                      80112                                  Atrial
                                                             Fibrillatio
                                                             n: Beating
                                                             Your Odds''
------------------------------------------------------------------------
Monetary    New      444 W.            $6,000    3/17/2014  Support
             Founda   Frontag                                Health and
             tion     e Road                                 Wellness
             Center   Northfi                                Program,
                      eld, IL                                benefitting
                      60093--                                clients who
                      3009                                   are
                                                             managing a
                                                             co-morbid
                                                             diagnosis
------------------------------------------------------------------------
Monetary    New      275 Rt.           $4,000    3/17/2014  New Jersey
             Jersey   10                                     Parent's
             Parent   East,                                  Caucus
             s        Suite                                  Outreach RV
             Caucus   220-414                                Tour and
                      Succasu                                Professiona
                      nna, NJ                                l Parent
                      07876                                  Advocacy
                                                             Training
                                                             Program
------------------------------------------------------------------------
Monetary    NewBrid  PO Box            $2,000     7/1/2014  Day
             ge       336 (7                                 Treatment
             Servic   Industr                                Program for
             es,      ial                                    Adults
             Inc.     Road,
                      Pequann
                      ock, NJ
                      07440)
                      Pompton
                      Plains,
                      NJ
                      07444
------------------------------------------------------------------------
Monetary    NHS      620 E.            $5,000    5/27/2014  Hollywood
             Human    Germant                                Beauty
             Servic   own                                    Salon
             es       Pike                                   Documentary
             Founda   Lafayet                                Project--po
             tion     te                                     st
             Inc      Hill,                                  production
                      PA                                     costs
                      19444
------------------------------------------------------------------------
Monetary    Northea  334               $2,500    8/26/2014  Healthy Food
             st       River                                  for Healthy
             Organi   Road                                   Communities
             c        Hillsbo
             Farmin   rough,
             g        NJ
             Associ   08844
             ation
             of NJ
------------------------------------------------------------------------
Monetary    Notre    1835                $100    8/18/2014  Memorial
             Dame     Catasau                                donation
             of       qua
             Bethle   Road
             hem      Bethleh
             School   em, PA
                      18018
------------------------------------------------------------------------
Monetary    Oldies   PO Box               $75    3/17/2014  Employee
             But      361                                    directed
             Goodie   Newingt                                donation in
             s        on, VA                                 lieu of
             Cocker   22122                                  company
             Rescue                                          holiday
             , Inc.                                          gift
------------------------------------------------------------------------
Monetary    One      1977              $3,500   11/17/2014  Wish
             Simple   North                                  Program:
             Wish     Olden                                  Education
                      Ave,                                   Fund for
                      #292                                   Aging Out
                      Trenton                                Youth
                      , NJ
                      08618
------------------------------------------------------------------------
Monetary    Open     14 Lake           $2,000    7/18/2014  Support to
             Road     Court                                  provide the
                      Fleming                                homebound
                      ton, NJ                                elderly and
                      08822                                  people with
                                                             disabilitie
                                                             s or mental
                                                             illness
                                                             with
                                                             stimulating
                                                             and
                                                             enriching
                                                             activities
                                                             that would
                                                             otherwise
                                                             be
                                                             unavailable
                                                             to them
------------------------------------------------------------------------
Monetary    Our      2626 E              $100     8/4/2014  Memorial
             Hospic   17th                                   Donation
             e of     Street
             South    Columbu
             Centra   s, IN
             l        47201
             Indian
             a
------------------------------------------------------------------------
Monetary    Passage  211               $5,000   12/15/2014  The State
             Theatr   Mercer                                 Street
             e        Street                                 Project
             Compan   PO Box
             y Inc.   967
                      Trenton
                      , NJ
                      08611
------------------------------------------------------------------------
Monetary    PEI      231                 $300     8/4/2014  Cost
             Kids     Lawrenc                                associated
                      e Road                                 with 2014
                      Lawrenc                                Janssen
                      eville,                                Cares
                      NJ                                     volunteer
                      08648                                  activity
------------------------------------------------------------------------
Monetary    PEI      231              $17,500   10/14/2014  Comprehensiv
             Kids     Lawrenc                                e Juvenile
                      e Road                                 Offenders
                      Lawrenc                                Outreach
                      eville,                                Services
                      NJ                                     (CJOOS)
                      08648                                  program
------------------------------------------------------------------------
Monetary    Penning  PO Box            $1,000    5/30/2014  Fundrasining
             ton      628                                    event
             Day,     Penning                                support to
             Inc.     ton, NJ                                benefit
                      08534                                  general
                                                             mission of
                                                             organizatio
                                                             n
------------------------------------------------------------------------
Monetary    People   140 East          $2,500   10/22/2014  People and
             And      Hanover                                Stories
             Storie   Street                                 with Mercer
             s--Gen   Trenton                                County
             te Y     , NJ                                   Seniors
             Cuento   08608
             s Inc.
------------------------------------------------------------------------
Monetary    Planned  PO Box            $4,000     7/1/2014  Whole-Health
             Living   4755                                   and
             Assist   Austin,                                Wellness
             ance     TX                                     Program
             Networ   78765
             k of
             Centra
             l
             Texas
------------------------------------------------------------------------
Monetary    Planned  13151             $2,500    8/26/2014  Education
             Living   Emily                                  and Social
             Assist   Road,                                  Skills
             ance     Suite                                  Development
             Networ   240                                    Program
             k of     Dallas,
             North    TX
             Texas,   75240
             Inc.
------------------------------------------------------------------------
Monetary    Plansma  118 West          $3,500    9/16/2014  2014
             rt NJ    State                                  Corporate
                      Trenton                                membership
                      , NJ                                   renewal
                      08608                                  donation to
                                                             support
                                                             efforts
                                                             around
                                                             sound land
                                                             use
                                                             planning
------------------------------------------------------------------------
Monetary    Princet  15               $25,000   12/12/2014  Path to
             on       Princes                                Impact--Cap
             Area     s Road                                 acity
             Commun   Lawrenc                                Building
             ity      eville,                                Program
             Founda   NJ
             tion,    08648
             Inc.
------------------------------------------------------------------------
Monetary    Princet  123 E.           $15,000   11/17/2014  Hunger
             on       Hanover                                Prevention
             Outrea   St.                                    and
             ch       Trenton                                Nutrition
             Projec   , NJ                                   Education
             ts /     08608                                  ($10,000)
             Crisis                                          and Housing
             Minist                                          Stability
             ry of                                           Services
             Mercer                                          ($5,000)
             County
------------------------------------------------------------------------
Monetary    Princet  45                $2,500   10/29/2014  Living
             on       Stockto                                Healthy for
             Senior   n St                                   Older
             Resour   Princet                                Adults
             ce       on, NJ
             Center   08540
------------------------------------------------------------------------
Monetary    Princet  350              $10,000    9/22/2014  United
             on-      Alexand                                Leaders of
             Blairs   er Road                                Tomorrow
             town     Princet                                (ULOT) at
             Center   on, NJ                                 Trenton
             Inc.     08540                                  Central
                                                             High School-
                                                             West Campus
------------------------------------------------------------------------
Monetary    Printma  440               $5,000   10/20/2014  Roving Press
             king     River
             Center   Road
             of New   Branchb
             Jersey   urg, NJ
                      08876
------------------------------------------------------------------------
Monetary    Printma  440              $15,000   10/20/2014  Combat Paper
             king     River                                  NJ
             Center   Road
             of New   Branchb
             Jersey   urg, NJ
                      08876
------------------------------------------------------------------------
Monetary    Project  1515              $5,000    7/18/2014  Mental
             HOME     Fairmou                                Health/
                      nt                                     Recovery
                      Avenue                                 Treatment
                      Philade                                Services
                      lphia,                                 for Adults
                      PA                                     Who Have
                      19130                                  Experienced
                                                             Homelessnes
                                                             s
------------------------------------------------------------------------
Monetary    Raritan  P.O. Box          $8,000   11/17/2014  WaterWays
             Headwa   273                                    Environment
             ters     Gladsto                                al
             Associ   ne, NJ                                 Education
             ation    07934                                  Program
------------------------------------------------------------------------
Monetary    Raritan  118              $20,000    11/5/2014  Promoting
             Valley   Lamingt                                Access to
             Commun   on Road                                STEM and
             ity      Branchb                                Nursing
             Colleg   urg, NJ                                Education
             e        08876                                  at Raritan
             Founda                                          Valley
             tion                                            Community
                                                             College:
                                                             Nursing
                                                             Scholarship
                                                             s
                                                             ($10,000),
                                                             Galileo
                                                             Scholarship
                                                             s ($5,000),
                                                             Textbooks
                                                             ($2,500),
                                                             STEM
                                                             Institute
                                                             ($2,500)
------------------------------------------------------------------------
Monetary    Regions  640               $5,000     5/9/2014  Mental
             Hospit   Jackson                                Health Drug
             al       Street                                 Assistance
             Founda   St.                                    Program
             tion     Paul,
                      MN
                      55101
------------------------------------------------------------------------
Monetary    Regions  640              $12,500     5/9/2014  Make It OK
             Hospit   Jackson                                Campaign to
             al       Street                                 fight
             Founda   St.                                    stigma
             tion     Paul,
                      MN
                      55101
------------------------------------------------------------------------
Monetary    Rescue   98               $25,000    9/22/2014  Emergency
             Missio   Carroll                                Services
             n of     Street,                                program
             Trento   PO Box
             n        790
                      Trenton
                      , NJ
                      08605
------------------------------------------------------------------------
Monetary    Resourc  427                 $300     8/4/2014  Cost
             e        Homeste                                associated
             Center   ad Road                                with 2014
             Of       Hillsbo                                Janssen
             Somers   rough,                                 Cares
             et,      NJ                                     volunteer
             Inc      08844                                  activity
------------------------------------------------------------------------
Monetary    Rider    2083             $20,000    11/5/2014  Urban STEM
             Univer   Lawrenc                                ($10,000),
             sity     eville                                 Janssen
                      Road                                   Science and
                      Lawrenc                                Business
                      eville,                                Scholarship
                      NJ                                     s ($7,500),
                      08648                                  Environment
                                                             al
                                                             Symposium
                                                             ($2,500)
------------------------------------------------------------------------
Monetary    Riverbe  PO Box            $5,000     7/1/2014  In-SHAPE
             nd       2032                                   Program
             Commun   Concord
             ity      , NH
             Mental   03302-
             Health   2032
             Inc
------------------------------------------------------------------------
Monetary    Riversi  4 South           $7,500   10/20/2014  Riverside
             de       Union                                  Symphonia
             Sympho   Street                                 Senior
             nia      P.O.                                   Outreach
             Inc      Box 650                                Program
                      Lambert
                      ville,
                      NJ
                      08530
------------------------------------------------------------------------
Monetary    San      2789              $5,000    5/27/2014  San
             Franci   25th                                   Francisco
             sco      Street                                 Collaborati
             Genera   Suite                                  ve Court's
             l        2028 PO                                Behavioral
             Hospit   Box                                    Health
             al       410836                                 Court--Supp
             Founda   San                                    orted
             tion     Francis                                Employment
                      co, CA                                 and
                      94110                                  Motivationa
                                                             l
                                                             Incentives
                                                             Program
------------------------------------------------------------------------
Monetary    Schizop  PO Box            $2,500    8/15/2014  2014
             hrenia   941222                                 National
             And      Houston                                Conference,
             Relate   , TX                                   ``Call to
             d        77094-                                 Action:
             Disord   8222                                   Shattering
             ers                                             Stigma''
             Allian
             ce Of
             Americ
             a
------------------------------------------------------------------------
Monetary    SERV     20                $5,000    5/27/2014  12th Annual
             Founda   Scotch                                 SERV
             tion,    Road                                   Recovery NJ
             Inc.     Ewing,                                 conference
                      NJ
                      08628
------------------------------------------------------------------------
Monetary    SERV     20                $5,000    5/27/2014  SERV
             Founda   Scotch                                 Foundation
             tion,    Road                                   Scholarship
             Inc.     Ewing,                                 Fund
                      NJ
                      08628
------------------------------------------------------------------------
Monetary    Shannon  PO Box              $500    8/28/2014  Donation in
             Daley    1271 36                                lieu of
             Memori   Indian                                 event
             al       Run                                    sponsorship
             Fund     Whiteho                                to help
                      use                                    local area
                      Station                                residents
                      , NJ                                   battling
                      08889                                  serious
                                                             ailments
                                                             and their
                                                             families
                                                             facing
                                                             hardship
------------------------------------------------------------------------
Monetary    Sharing  1920              $2,000    7/31/2014  Art program
             Place    10th                                   at the 1920
             Inc      Avenue                                 Club
                      South
                      P.O.
                      Box
                      55945
                      Birming
                      ham, AL
                      35255
------------------------------------------------------------------------
Monetary    Sisters  1201              $1,000     2/3/2014  Blue Ribbon
             Networ   Hamilto                                sponsor
             k of     n                                      2014 Health
             Centra   Street                                 Summit and
             l New    Somerse                                Breakfast
             Jersey   t, NJ
                      08873
------------------------------------------------------------------------
Monetary    Sisters  1201              $5,000    8/28/2014  Fundraising
             Networ   Hamilto                                event
             k of     n                                      support to
             Centra   Street                                 benefit
             l New    Somerse                                general
             Jersey   t, NJ                                  mission of
                      08873                                  organizatio
                                                             n
------------------------------------------------------------------------
Monetary    Somerse  PO Box              $100   11/12/2014  Memorial
             t        3000                                   donation
             County   Somervi
             Office   lle, NJ
             on       08876-
             Aging    1262
------------------------------------------------------------------------
Monetary    Somerse  49                  $680     2/3/2014  General
             t Home   Brahma                                 Operating
             for      Avenue                                 Support
             Tempor   Bridgew
             arily    ater,
             Displa   NJ
             ced      08807
             Childr
             en
------------------------------------------------------------------------
Monetary    Somerse  49                $7,500   10/20/2014  Street
             t Home   Brahma                                 Smart--HIV
             for      Avenue                                 Prevention
             Tempor   Bridgew                                program
             arily    ater,                                  within
             Displa   NJ                                     Somerset
             ced      08807                                  county
             Childr
             en
------------------------------------------------------------------------
Monetary    St.      501 St              $100    1/14/2014  Memorial
             Jude's   Jude                                   Donation
             Childr   Place
             en's     Memphis
             Resear   , TN
             ch       38105
             Hospit
             al
------------------------------------------------------------------------
Monetary    St.      One              $15,000   10/20/2014  Providing
             Mary     Summit                                 Food for
             Medica   Square,                                School-Age
             l        Suite                                  Children
             Center   300                                    Living in
             Founda   1717                                   Poverty:
             tion     Langhor                                The St.
                      ne-                                    Mary
                      Newtown                                Backpacks
                      Road                                   for Kids
                      Langhor                                Program
                      ne, PA
                      19047
------------------------------------------------------------------------
Monetary    Stony    31 Titus         $15,000    11/5/2014  StreamWatch:
             Brook    Mill                                   Science in
             Millst   Road                                   the Service
             one      Penning                                of
             Waters   ton, NJ                                Conservatio
             hed      08534                                  n
             Associ
             ation
------------------------------------------------------------------------
Monetary    SWIM     120               $2,000    9/22/2014  Program
             Inc.     Findern                                Development
                      e                                      Project in
                      Avenue                                 Somerset
                      Bridgew                                and
                      ater,                                  Hunterdon
                      NJ                                     Counties--V
                      08807                                  olunteer
                                                             Training in
                                                             aquatic
                                                             exercise
                                                             for the
                                                             disabled,
                                                             administrat
                                                             ive
                                                             training
                                                             for
                                                             coordinator
                                                             s and co-
                                                             coordinator
                                                             s, and
                                                             sensitivity
                                                             training
------------------------------------------------------------------------
Monetary    TASK,    72\1/2\          $25,000   10/14/2014  TASK Meal
             Inc.     Escher                                 Service
                      Street,                                Program
                      P.O.
                      Box 872
                      Trenton
                      , NJ
                      08605
------------------------------------------------------------------------
Monetary    The      Paul              $9,500    10/1/2014  Arts Council
             Arts     Robeson                                of
             Counci   Center                                 Princeton
             l of     for the                                Community
             Prince   Arts                                   Outreach
             ton      102                                    programs
                      Withers                                for youth
                      poon                                   and seniors
                      Street
                      Princet
                      on, NJ
                      08542
------------------------------------------------------------------------
Monetary    The      2020              $2,000   11/17/2014  Art for
             Center   Burnt                                  Special
             for      Mills                                  Needs
             Contem   Road                                   Children
             porary   Bedmins
             Art      ter, NJ
                      07921
------------------------------------------------------------------------
Monetary    The      19               $13,500    9/22/2014  Clinically-
             Center   Dellwoo                                managed,
             For      d Lane                                 residential
             Great    Somerse                                treatment
             Expect   t, NJ                                  program for
             ations   08873                                  homeless,
                                                             pregnant/
                                                             parenting
                                                             adult women
                                                             in
                                                             substance
                                                             use
                                                             recovery,
                                                             and their
                                                             children
                                                             ($10,000),
                                                             Annual Gala
                                                             ($3,500)
------------------------------------------------------------------------
Monetary    The      1040              $5,000     7/1/2014  Jail
             Edinbu   Waltham                                Diversion
             rg       Street                                 Program
             Center   Lexingt
                      on, MA
                      02421-
                      8033
------------------------------------------------------------------------
Monetary    The      8150 N.          $40,000   11/17/2014  HeartGuide--
             Mended   Central                                Patient
             Hearts   Express                                Resource
             , Inc.   way,                                   and
                      Suite                                  Visiting
                      M2248                                  Program
                      Dallas,
                      TX
                      75206
------------------------------------------------------------------------
Monetary    The      401                 $500    1/14/2014  Flash Lite
             Mental   Cypress                                sponsor
             Health   Street                                 2014 Lite
             Center   Manches                                Up The Nite
             Of       ter, NH                                Run/Walk
             Greate   03103                                  for Mental
             r                                               Health 5k
             Manche
             ster
------------------------------------------------------------------------
Monetary    The      400                 $300    8/26/2014  Costs
             Pennsb   Pennsbu                                associated
             ury      ry                                     with 2014
             Societ   Memoria                                Janssen
             y        l Road                                 Cares
                      Morrisv                                volunteer
                      ille,                                  activity
                      PA
                      19067
------------------------------------------------------------------------
Monetary    The      P.O. Box          $5,000    12/3/2014  The
             Prince   2063                                   Princeton
             ton      Princet                                Festival
             Festiv   on, NJ                                 Intergenera
             al       08543                                  tional
                                                             Opera
                                                             Workshop
                                                             for Teens
                                                             and their
                                                             Families
------------------------------------------------------------------------
Monetary    Thomas   101 West         $10,000    11/5/2014  Scholarships
             Edison   State                                  for Nursing
             State    Street                                 Students
             Colleg   Trenton                                Enrolled in
             e        , NJ                                   Thomas
             Founda   08608                                  Edison
             tion                                            State
                                                             College's
                                                             Accelerated
                                                             Second
                                                             Degree BSN
                                                             Program.
------------------------------------------------------------------------
Monetary    Trenton  PO Box            $1,500    9/22/2014  Financial
             Commun   5206                                   Aid to
             ity      Trenton                                subsidize
             Music    , NJ                                   tuition
             School   08638                                  costs for
                                                             families
                                                             qualifying
                                                             based on
                                                             family size
                                                             and income--
                                                             music
                                                             instruction
                                                             s for
                                                             students
------------------------------------------------------------------------
Monetary    Trenton  635               $3,500   11/17/2014  Trenton
             Educat   South                                  Education
             ion      Clinton                                Dance
             Dance    Avenue                                 Institute
             Instit   Trenton                                program for
             ute      , NJ                                   at-risk
                      08611                                  youth in
                                                             Trenton
------------------------------------------------------------------------
Monetary    Trenton  218 N            $10,000   10/23/2014  Inroads for
             Health   Broad                                  Health:
             Team     St                                     Taking it
             Inc      Trenton                                to the
                      , NJ                                   Streets
                      08608
------------------------------------------------------------------------
Monetary    Trinity  22                $9,000   11/17/2014  Mental
             Counse   Stockto                                Health and
             ling     n                                      Wellness
             Servic   Street                                 Programs
             es       Trinity
                      Counsel
                      ing
                      Service
                      Princet
                      on, NJ
                      08540
------------------------------------------------------------------------
Monetary    Truist/  Departme         $32,261   12/12/2014  Truist
             Fronts   nt                                     processing
             tream,   CH16952                                fee for
             Inc.     Palatin                                total 2014
                      e, IL                                  United Way
                      60055-                                 Campaign
                      6952                                   (fee
                                                             associated
                                                             with NJ
                                                             companies)
------------------------------------------------------------------------
Monetary    Twiligh  P.O. Box          $5,000   11/17/2014  Simple Needs
             t Wish   1042 11                                Wish
             Founda   Duane                                  Granting
             tion     Road                                   Program
                      Doylest                                Expansion
                      own, PA
                      18901
------------------------------------------------------------------------
Monetary    UIH      4 North           $7,500   10/14/2014  Community of
             Family   Broad                                  Health for
             Partne   Street                                 Men
             rs       2nd
                      Floor
                      Trenton
                      , NJ
                      08618-
                      4408
------------------------------------------------------------------------
Monetary    United   9-25              $9,000    8/26/2014  Princeton
             Negro    Alling                                 Committee
             Colleg   St.                                    of UNCF
             e Fund   Second                                 Scholarship
                      Floor                                  -Scholarshi
                      Newark,                                p support
                      NJ                                     for
                      07102                                  deserving
                                                             STEM
                                                             students in
                                                             Mercer or
                                                             Somerset
                                                             Counties
------------------------------------------------------------------------
Monetary    United   P.O. Box        $607,875   12/12/2014  Company
             Way      418607                                 match to
             Worldw   Boston,                                employee
             ide      MA                                     United Way
                      02241-                                 campaign
                      8607                                   for NJ
                                                             based
                                                             commercial
                                                             companies
                                                             of Janssen
                                                             Pharmaceuti
                                                             cal
                                                             Companies
                                                             of Johnson
                                                             & Johnson
                                                             less Truist
                                                             processing
                                                             fee
------------------------------------------------------------------------
Monetary    US Pain  670               $7,500    12/4/2014  INvisible
             Founda   newfiel                                Project
             tion     d
                      street
                      suite b
                      middlet
                      own, CT
                      06457
------------------------------------------------------------------------
Monetary    Valeo    5401 SW           $5,000    7/18/2014  Services for
             Behavi   7th                                    Employment
             oral     Street                                 Success
             Health   Topeka,                                Program
             Care     KS                                     serving
             Inc      66606                                  consumers
                                                             with
                                                             Schizophren
                                                             ia and
                                                             other
                                                             severe
                                                             mental
                                                             illness
------------------------------------------------------------------------
Monetary    Volunte  P.O. Box          $8,500    10/1/2014  SkillsConnec
             er       615                                    t skills
             Connec   Princet                                based
             t        on, NJ                                 community
                      08542                                  volunteer
                                                             program
------------------------------------------------------------------------
Monetary    West     120               $2,000     7/1/2014  Young Adults
             Bergen   Chestnu                                with
             Mental   t                                      Schizophren
             Health   Street                                 ia Young
             care     Ridgewo                                Adult Track
                      od, NJ                                 of the
                      07450-                                 Partial
                      2500                                   Care
                                                             Program
------------------------------------------------------------------------
Monetary    West     120                 $300     8/4/2014  Cost
             Bergen   Chestnu                                associated
             Mental   t                                      with 2014
             Health   Street                                 Janssen
             care     Ridgewo                                Cares
                      od, NJ                                 Volunteer
                      07450-                                 Activity
                      2500
------------------------------------------------------------------------
Monetary    West     PO Box            $5,000    9/22/2014  STEM
             Windso   280                                    Excellence
             r        West                                   in
             Plains   Windsor                                Education
             boro     , NJ                                   Grant
             Educat   08550-                                 Program
             ion      0280
             Founda
             tion
------------------------------------------------------------------------
Monetary    Womansp  1530              $2,500   10/20/2014  Emergency
             ace      Brunswi                                Domestic
                      ck                                     Violence
                      Avenue                                 Shelter
                      Lawrenc                                program
                      eville,
                      NJ
                      08648
------------------------------------------------------------------------
Monetary    Wounded  4899                $100    5/16/2014  Memorial
             Warrio   Belfort                                Donation
             r        Road
             Projec   Suite
             t        300
                      Jackson
                      ville,
                      FL
                      32256
------------------------------------------------------------------------
Monetary    Wounded  4899                 $75    12/3/2014  Employee
             Warrio   Belfort                                directed
             r        Road                                   donation in
             Projec   Suite                                  lieu of
             t        300                                    company
                      Jackson                                holiday
                      ville,                                 gift
                      FL
                      32256
------------------------------------------------------------------------
Monetary    YMCA of  431               $7,500   12/10/2014  The YMCA of
             Trento   Penning                                Trenton's
             n        ton                                    Stars of
                      Avenue                                 Science
                      Trenton                                Program
                      , NJ
                      08618
------------------------------------------------------------------------
Monetary    Young    349 W.            $3,500   10/20/2014  College
             Schola   State                                  Preparatory
             rs'      St                                     Program
             Instit   Trenton
             ute      , NJ
                      08618
------------------------------------------------------------------------
Monetary    YWCA     59 Paul           $3,000   11/17/2014  Breast
             Prince   Robeson                                Cancer
             ton      Place                                  Resource
                      Princet                                Center--Wom
                      on, NJ                                 en of
                      08540                                  Wisdom
                                                             (WOW)
                                                             Program
------------------------------------------------------------------------
Product     AmeriCa  88              $490,904    3/19/2014  Product
             res      Hamilto                                Donation
             Founda   n                                      for
             tion     Avenue                                 Humanitaria
                      Stamfor                                n Relief in
                      d, CT                                  the U.S.,
                      06902                                  El
                                                             Salvador,
                                                             Guatemala,
                                                             Honduras,
                                                             Nicaragua,
                                                             Cambodia,
                                                             Pakistan,
                                                             and Peru.
------------------------------------------------------------------------
Product     AmeriCa  88              $834,365    3/19/2014  Product
             res      Hamilto                                Donation
             Founda   n                                      for
             tion     Avenue                                 Humanitaria
                      Stamfor                                n Relief in
                      d, CT                                  Guatemala,
                      06902                                  El
                                                             Salvador,
                                                             Honduras,
                                                             Nicaragua.
------------------------------------------------------------------------
Product     AmeriCa  88              $383,214   10/23/2014  Product
             res      Hamilto                                Donation in
             Founda   n Ave                                  support of
             tion     Stamfor                                Disaster
                      d, CT                                  Response
                      06902
------------------------------------------------------------------------
Product     AmeriCa  88              $233,871    12/3/2014  Product
             res      Hamilto                                donation
             Founda   n Ave                                  for
             tion     Stamfor                                humanitaria
                      d, CT                                  n
                      06902                                  assistance
                                                             in Malawi,
                                                             Tanzania,
                                                             West Bank,
                                                             Armenia,
                                                             Dominican
                                                             Republic,
                                                             El
                                                             Salvador,
                                                             Guatemala,
                                                             Nicaragua,
                                                             Peru,
                                                             Tanzania
------------------------------------------------------------------------
Product     AmeriCa  88              $100,985    12/3/2014  Product
             res      Hamilto                                donation
             Founda   n Ave                                  for
             tion     Stamfor                                humanitaria
                      d, CT                                  n
                      06902                                  assistance
                                                             in Malawi,
                                                             Tanzania,
                                                             Armenia,
                                                             Dominican
                                                             Republic,
                                                             Colombia
------------------------------------------------------------------------
Product     AmeriCa  88              $825,981    11/6/2014  Product
             res      Hamilto                                Donations
             Founda   n Ave                                  for
             tion     Stamfor                                Humanitaria
                      d, CT                                  n Aid for
                      06902                                  Armenia,
                                                             Dominican
                                                             Republic,
                                                             Gaza,
                                                             Pakistan,
                                                             West Bank
                                                             and
                                                             Tanzania.
------------------------------------------------------------------------
Product     AmeriCa  88            $2,389,565     8/4/2014  Product
             res      Hamilto                                Donation in
             Founda   n Ave                                  support of
             tion     Stamfor                                Humanitan
                      d, CT                                  Aid for the
                      06902                                  U.S.,
                                                             Afghanistan
                                                             ,
                                                             Bangladesh,
                                                             Pakistan,
                                                             and Peru.
------------------------------------------------------------------------
Product     Catholi  33-01             $5,279    12/3/2014  Pharmaceutic
             c        Elevent                                al Product
             Medica   h                                      Donation
             l        Street                                 for
             Missio   Long                                   Humanitaria
             n        Island                                 n Aid in
             Board    City,                                  Haiti
                      NY
------------------------------------------------------------------------
Product     Direct   27 S. La        $665,263    3/19/2014  Product
             Relief   Patera                                 Donation to
             Intern   Lane                                   support
             ationa   Santa                                  Humanitaria
             l        Barbara                                n Relief in
                      , CA                                   Haiti,
                      93117                                  Dominican
                                                             Republic,
                                                             Honduras,
                                                             Paraguay,
                                                             and
                                                             Nicaragua.
------------------------------------------------------------------------
Product     Direct   27 S. La        $614,185    3/19/2014  Product
             Relief   Patera                                 Donation to
             Intern   Lane                                   support
             ationa   Santa                                  Humanitaria
             l        Barbara                                n Relief in
                      , CA                                   Haiti,
                      93117                                  Dominican
                                                             Republic,
                                                             and
                                                             Paraguay.
------------------------------------------------------------------------
Product     Direct   27 S. La        $116,610    2/27/2014  Humanitarian
             Relief   Patera                                 Aid for
             Intern   Lane                                   Obstetric
             ationa   Santa                                  Fistula
             l        Barbara                                program.
                      , CA
                      93117
------------------------------------------------------------------------
Product     Direct   27 S. La        $322,359    11/6/2014  Humanitarian
             Relief   Patera                                 Aid for
             Intern   Lane                                   Ghana,
             ationa   Santa                                  Paraguay,
             l        Barbara                                and Peru.
                      , CA
                      93117
------------------------------------------------------------------------
Product     Direct   27 S. La      $2,354,643    12/3/2014  Pharmaceutic
             Relief   Patera                                 al Product
             Intern   Lane                                   Donation
             ationa   Santa                                  for
             l        Barbara                                Disaster
                      , CA                                   Response
                      93117                                  and/or
                                                             Humanitaria
                                                             n Aid in
                                                             Dominican
                                                             Republic,
                                                             Guatemala,
                                                             Nicaragua,
                                                             Peru,
                                                             Panama,
                                                             Paraguay
                                                             and United
                                                             States
------------------------------------------------------------------------
Product     Direct   27 S. La         $30,164    12/3/2014  Pharmaceutic
             Relief   Patera                                 al Product
             Intern   Lane                                   Donation
             ationa   Santa                                  for
             l        Barbara                                Humanitaria
                      , CA                                   n Aid in
                      93117                                  Nicaragua,
                                                             Peru
------------------------------------------------------------------------
Product     Direct   27 S. La      $2,093,905     8/5/2014  Humanitarian
             Relief   Patera                                 Aid for
             Intern   Lane                                   Haiti,
             ationa   Santa                                  Paraguay,
             l        Barbara                                and U.S.
                      , CA
                      93117
------------------------------------------------------------------------
Product     Heart    1021             $72,493    3/19/2014  Product
             to       Pacific                                Donation
             Heart    Avenue                                 for
             Intern   Kansas                                 Humanitaria
             ationa   City,                                  n Relief in
             l        KS                                     Papua New
                      66102                                  Guinea and
                                                             Cameroon.
------------------------------------------------------------------------
Product     Heart    1021             $33,156   12/18/2014  Pharmaceutic
             to       Pacific                                al Product
             Heart    Avenue                                 donation
             Intern   Kansas                                 for Ebola
             ationa   City,                                  Treatment
             l        KS                                     Unit in
                      66102                                  Liberia
------------------------------------------------------------------------
Product     Heart    1021             $46,435    12/3/2014  Pharmaceutic
             to       Pacific                                al Product
             Heart    Avenue                                 donation
             Intern   Kansas                                 for
             ationa   City,                                  humanitaria
             l        KS                                     n relief in
                      66102                                  Papua New
                                                             Guinea
------------------------------------------------------------------------
Product     Johnson  One         $380,566,479    3/15/2014  Patient
             &        Johnson                                Assistance
             Johnso   &                                      Product
             n        Johnson                                Donation
             Patien   Plaza
             t        New
             Assist   Brunswi
             ance     ck, NJ
             Founda   08933
             tion
------------------------------------------------------------------------
Product     Johnson  One          $87,387,455   12/15/2014  Patient
             &        Johnson                                Assistance
             Johnso   &                                      Product
             n        Johnson                                Donation
             Patien   Plaza
             t        New
             Assist   Brunswi
             ance     ck, NJ
             Founda   08933
             tion
------------------------------------------------------------------------
Product     Johnson  One          $74,577,911    9/15/2014  Patient
             &        Johnson                                Assistance
             Johnso   &                                      Product
             n        Johnson                                Donation
             Patien   Plaza
             t        New
             Assist   Brunswi
             ance     ck, NJ
             Founda   08933
             tion
------------------------------------------------------------------------
Product     MAP      4700            $772,428     1/9/2014  Donation for
             Intern   Glynco                                 Medical
             ationa   Parkway                                Mission
             l        Brunswi                                Pack Plus
                      ck, GA                                 Program
                      31525
------------------------------------------------------------------------
Product     MAP      4700             $26,142     1/9/2014  Donation for
             Intern   Glynco                                 the Medical
             ationa   Parkway                                Mission
             l        Brunswi                                Pack Plus
                      ck, GA                                 Program
                      31525
------------------------------------------------------------------------
Product     MAP      4700             $26,394    12/3/2014  Pharmaceutic
             Intern   Glynco                                 al Product
             ationa   Parkway                                Donation to
             l        Brunswi                                support the
                      ck, GA                                 Medical
                      31525                                  Mission
                                                             Pack Plus
------------------------------------------------------------------------
Product     Mercy    15862             $8,397    3/19/2014  Product
             Ships    State                                  Donation in
             Intern   Highway                                support of
             ationa   110                                    Humanitaria
             l        North                                  n Relief in
             Operat   Lindale                                West
             ions     , TX                                   Africa.
             Center   75771
------------------------------------------------------------------------
Product     New      1                $13,297     8/4/2014  Product
             Jersey   Riversi                                Donation.
             Academ   de
             y of     Drive
             Aquati   Camden,
             c        NJ
             Scienc   08103-
             es       1037
------------------------------------------------------------------------
Product     Project  255             $149,962    3/19/2014  Product
             Hope     Carter                                 Donation in
                      Hall                                   support of
                      Lane                                   Humanitaria
                      Millwoo                                n Relief in
                      d, VA                                  Kosovo,
                      22646                                  Macedonia,
                                                             and
                                                             Tajikistan.
------------------------------------------------------------------------
Product     Project  255             $768,245    3/10/2014  Product
             Hope     Carter                                 Donation
                      Hall                                   for
                      Lane                                   Humanitaria
                      Millwoo                                n Relief in
                      d, VA                                  Tajikistan.
                      22646
------------------------------------------------------------------------
Product     Project  255             $821,994    3/10/2014  Product
             Hope     Carter                                 Donation
                      Hall                                   for
                      Lane                                   Humanitaria
                      Millwoo                                n Aid in
                      d, VA                                  Tajikistan.
                      22646
------------------------------------------------------------------------
Similar payments to the same organization may appear in this report as
  contributions may be distributed in multiple payments.


  Janssen Therapeutics, Division of Janssen Products, LP, Monetary and
 Product Contributions to U.S.-based Charitable Organizations Full Year
                                  2014
(Payments made from January 1, 2014 to December 31, 2014)--Amended March
                                19, 2019
------------------------------------------------------------------------
                                                               Project
 Donation    Payee     Payee   Payment Amount    Payment       Title/
   Type               Address       (USD)          Date      Description
------------------------------------------------------------------------
Monetary    Aboundi  South             $1,500    3/24/2014  HEALTHY U! .
             ng       Bouleva                                . . HEALTHY
             Prospe   rd                                     US!
             rty      Dallas,
                      TX
                      75215
------------------------------------------------------------------------
Monetary    Acercam  827               $7,000    6/16/2014  ContraSIDA
             iento    Wildwoo                                (Against
             Hispan   d                                      AIDS)
             o de     Avenue
             Caroli   Suite
             na del   200
             Sur      Columbi
                      a, SC
                      29203
------------------------------------------------------------------------
Monetary    Aid for  515               $5,000    11/7/2014  New York
             AIDS     Greenwi                                Immigrant
             Intern   ch                                     AIDS Link
             ationa   Street                                 Program
             l        New
                      York,
                      NY
                      10013
------------------------------------------------------------------------
Monetary    AIDS     75 Amory         $10,000    11/7/2014  Viral
             Action   Street                                 Hepatitis
             Commit   Boston,                                Access
             tee      MA                                     Project
                      02119                                  (VHAP)
------------------------------------------------------------------------
Monetary    AIDS     75 Amory         $15,000     3/5/2014  Mental
             Action   Street                                 Health
             Commit   Boston,                                Program/
             tee      MA                                     Charitable
                      02119                                  Contributio
                                                             n
------------------------------------------------------------------------
Monetary    Aids     575              $20,000     7/9/2014  HIV Health
             Commun   Eighth                                 Literacy
             ity      Avenue                                 Program
             Resear   Suite                                  (HHLP)
             ch       502 New
             Initia   York,
             tive     NY
             of       10018
             Americ
             a
             (ACRIA
             )
------------------------------------------------------------------------
Monetary    AIDS     6260              $4,500   10/27/2014  Wall Talk
             Founda   Westpar                                HIV/
             tion     k Drive                                Hepatitis C
             Housto   Houston                                Co-
             n        , TX                                   Infection
                      77057
------------------------------------------------------------------------
Monetary    AIDS     411              $30,000    7/10/2014  Road to
             Founda   South                                  Health:
             tion     Wells                                  Promoting
             of       Street                                 Successful
             Chicag   Suite                                  Implementat
             o        300                                    ion of
                      Chicago                                Health Care
                      , IL                                   Reform for
                      60607                                  People
                                                             Living with
                                                             HIV/AIDS in
                                                             Illinois
------------------------------------------------------------------------
Monetary    AIDS     7215              $5,000   12/15/2014  Case
             Servic   Cameron                                Management
             e of     Road
             Austin   Austin,
                      TX
                      78752
------------------------------------------------------------------------
Monetary    AIDS     17982             $3,000    8/18/2014  HIV Medical
             Servic   Sky                                    Case
             es       Park                                   Management
             Center   Circle
             of       Irvine,
             Orange   CA
             County   92614
------------------------------------------------------------------------
Monetary    AIDS     7215              $5,000     4/4/2014  Case
             Servic   Cameron                                Management
             es of    Road                                   Program
             Austin   Austin,
                      TX
                      78752
------------------------------------------------------------------------
Monetary    AIDS     1424 K          $250,000   11/10/2014  Access to
             United   Street,                                Care (A2C)
                      NW                                     Initiative
                      Washing
                      ton, DC
                      20005
------------------------------------------------------------------------
Monetary    Allianc  825               $5,000     7/8/2014  Group Home
             e for    Colorad                                Care for
             Housin   o                                      Homeless
             g and    Bouleva                                Persons
             Healin   rd                                     with HIV/
             g        Suite                                  AIDS at
                      100 Los                                Soldano
                      Angeles                                House and
                      , CA                                   Casa de
                      90041                                  Corazon
------------------------------------------------------------------------
Monetary    Bay      701 Oak           $2,400    1/17/2014  Youth
             Area     Street                                 Engagement
             Young    San                                    Program/
             Positi   Francis                                Charitable
             ves      co, CA                                 contributio
                      94117                                  n
------------------------------------------------------------------------
Monetary    Bay      701 Oak           $5,000    11/7/2014  Patient Peer
             Area     Street                                 Navigator
             Young    San
             Positi   Francis
             ves      co, CA
                      94117
------------------------------------------------------------------------
Monetary    Bienest  5326 E           $15,000    11/5/2014  General
             ar       Beverly                                Organizatio
             Human    Road                                   nal Support
             Servic   Los
             es Inc   Angeles
                      , CA
                      90022
------------------------------------------------------------------------
Monetary    Caring   19591 S.         $20,000    8/18/2014  Patients
             Ambass   Alberta                                CHOICES--Ch
             adors    Beaverc                                anging
                      reek,                                  Hepatitis
                      OR                                     through
                      97004                                  Outreach,
                                                             Information
                                                             ,
                                                             Comprehensi
                                                             ve
                                                             Education,
                                                             and Support
------------------------------------------------------------------------
Monetary    Catholi  3009              $5,000    11/7/2014  The Home
             c        Lake                                   Place
             Charit   Brook
             ies of   Bouleva
             East     rd
             Tennes   Knoxvil
             see      le, TN
                      37909
------------------------------------------------------------------------
Monetary    Chicago  1925              $5,000    2/21/2014  Connect2Care
             House    North                                  (C2C) /
             and      Clybour                                Charitable
             Social   n Suite                                Contributio
             Servic   401                                    n
             e        Chicago
             Agency   , IL
                      60614
------------------------------------------------------------------------
Monetary    Chicago  1925             $10,000   12/15/2014  Connect2Care
             House    North
             and      Clybour
             Social   n Suite
             Servic   401
             e        Chicago
             Agency   , IL
                      60614
------------------------------------------------------------------------
Monetary    Christi  2440             $15,000   12/15/2014  CHANGE for
             e's      Third                                  Women
             Place    Avenue                                 Program
                      San
                      Diego,
                      CA
                      92101
------------------------------------------------------------------------
Monetary    Communi  677 Ala           $3,000    3/24/2014  HIV and Hep
             ty       Moana                                  C
             Health   Bouleva                                Prevention
             Outrea   rd                                     in Drug-
             ch       Suite                                  Using
             Work     226                                    Community/
             to       Honolul                                Charitable
             Preven   u, HI                                  Contributio
             t AIDS   96813                                  n
------------------------------------------------------------------------
Monetary    Desert   1695 N.           $5,000    1/17/2014  Case
             Aids     Sunrise                                Management/
             Projec   Way                                    Charitable
             t        Palm                                   Contributio
                      Springs                                n
                      , CA
                      92262
------------------------------------------------------------------------
Monetary    Fund     121              $25,000    11/5/2014  Get SMART
             For      Avenue                                 About
             The      of the                                 Hepatitis C
             City     America
             of New   s 6th
             York     Floor
             Inc      New
                      York,
                      NY
                      10013
------------------------------------------------------------------------
Monetary    Gay      446 West         $15,000    11/7/2014  Community
             Men's    33rd                                   Education
             Health   Street                                 and
             Crisis   New                                    Treatment
                      York,                                  as
                      NY                                     Prevention
                      10001                                  Program
------------------------------------------------------------------------
Monetary    HARM     South            $50,000    4/18/2014  Hepatitis C
             Reduct   Bouleva                                Innovations
             ion      rd                                     Network/
             Coalit   Dallas,                                Charitbale
             ion      TX                                     Contributio
                      75215                                  n
------------------------------------------------------------------------
Monetary    Health   1211             $75,000    3/17/2014  ``C Change''
             Federa   Chestnu                                Program
             tion     t
             of       Street
             Philad   Suite
             elphia   801
                      Philade
                      lphia,
                      PA
                      19107
------------------------------------------------------------------------
Monetary    Hep C    601              $15,000    6/17/2014  HepC
             Allian   Busines                                Education
             ce       s Loop                                 and
                      70 West                                Testing--Th
                      Columbi                                e Kansas
                      a, MO                                  Project
                      65203
------------------------------------------------------------------------
Monetary    Hep C    1325             $10,000    3/14/2014  Expanding
             Connec   South                                  Efforts to
             tion     Colorad                                Locate
                      o                                      Undiagnosed
                      Bouleva                                HCV
                      rd                                     Patients
                      Suite                                  and Link to
                      302                                    Care
                      Denver,
                      CO
                      80222
------------------------------------------------------------------------
Monetary    Hepatit  35 East          $25,000    7/25/2014  The
             is C     38th                                   Hepatitis C
             Mentor   Street                                 Patient
             and      New                                    Assistance
             Suppor   York,                                  Program
             t        NY
             Group,   10016
             Inc
------------------------------------------------------------------------
Monetary    HIV      100               $5,000    3/12/2014  The
             Aids     Edgewoo                                EmpowerLink
             Empowe   d                                      Program
             rment    Avenue
             Resour   NE
             ce       Suite
             Center   1020
             for      Atlanta
             Young    , GA
             Women,   30303-
             Inc.     3065
------------------------------------------------------------------------
Monetary    Housing  57                $5,000   11/13/2014  The
             Works    Willoug                                Undetectabl
                      hby                                    es--HIV
                      Street                                 Viral
                      Brookly                                Suppression
                      n, NY                                  Initiative
                      11201
------------------------------------------------------------------------
Monetary    Howard   4025 N.          $10,000    7/25/2014  Hepatitis C
             Brown    Sherida                                Medical
             Health   n                                      Management
             Center   Street                                 and Support
                      Chicago                                for People
                      , IL                                   who Inject
                      60613                                  Drugs
------------------------------------------------------------------------
Monetary    Iris     2348              $7,500    2/21/2014  Hepatitis C
             House    Adam                                   Testing,
                      Clayton                                Education
                      Powell                                 and
                      Jr                                     Connection
                      Bouleva                                to Care
                      rd New                                 programs/
                      York,                                  Charitbale
                      NY                                     Contributio
                      10030                                  n
------------------------------------------------------------------------
Monetary    J&J      One          $11,200,000   12/19/2014  Global
             Family   Johnson                                Public
             of       &                                      Health
             Compan   Johnson                                programs in
             ies      Plaza,                                 South
             Contri   New                                    Africa and
             bution   Brunswi                                Uganda (HIV
             s Fund   ck, NJ                                 and TB)
                      08933
------------------------------------------------------------------------
Monetary    Josephs  1730              $5,000    3/13/2014  Care and
             House    Lanier                                 Intensive
                      Place                                  Treatment
                      NW                                     Adherence
                      Washing                                Support for
                      ton, DC                                People with
                      20009                                  HIV
------------------------------------------------------------------------
Monetary    Kansas   3515              $5,000   12/15/2014  Reducing
             City     Broadwa                                Risks
             Free     y                                      through
             Health   Kansas                                 Health
             Clinic   City,                                  Education
                      MO
                      64111
------------------------------------------------------------------------
Monetary    Legacy   4054              $5,000   10/27/2014  Mission
             Counse   McKinne                                Support
             ling     y                                      Legacy
             Center   Avenue                                 Counseling
                      Dallas,                                Center
                      TX
                      75204
------------------------------------------------------------------------
Monetary    Maine    35                $5,000    6/23/2014  Harm
             Genera   Medical                                Reduction
             l        Center                                 Program:
             Health   Parkway                                HIV and HCV
                      Augusta                                Prevention
                      , ME
                      04330
------------------------------------------------------------------------
Monetary    Making   60 Clif           $5,000   12/15/2014  Imani Park
             It       Prescod                                Transitiona
             Possib   Lane                                   l Housing
             e to     Edison,                                Program
             End      NJ
             Homele   08817
             ssness
------------------------------------------------------------------------
Monetary    Minorit  5149              $7,500    2/21/2014  ``The Bridge
             y AIDS   West                                   Program''
             Projec   Jeffers
             t        on
                      Blvd.
                      Los
                      Angeles
                      , CA
                      90016
------------------------------------------------------------------------
Monetary    NAESM,   2140              $5,000    6/16/2014  The D.C.
             Inc.     Martin                                 Project
                      Luther
                      King Jr
                      Drive
                      Atlanta
                      , GA
                      30310
------------------------------------------------------------------------
Monetary    Nashvil  633               $5,000    5/13/2014  Outreach,
             le       Thompso                                Testing,
             CARES    n Lane                                 Linkage to
                      Nashvil                                Care, and
                      le, TN                                 Supportive
                      37204                                  Services
                                                             for young
                                                             AA gay/
                                                             bisexual or
                                                             other MSM
------------------------------------------------------------------------
Monetary    Nationa  2140              $7,000   12/15/2014  Project
             l AIDS   Martin                                 Impact
             Educat   Luther
             ion      King
             and      Jr. SW
             Servic   Atlanta
             es for   , GA
             Minori   30310
             ties
------------------------------------------------------------------------
Monetary    Nationa  580             $175,000    4/18/2014  NATAP HIV,
             l AIDS   Broadwa                                HCV/HIV
             Treatm   y Suite                                Coinfetion
             ent      1010                                   and Hep C
             Advoca   New                                    Care and
             cy       York,                                  Treatment
             Projec   NY                                     Education/
             t        10012                                  Information
             (NATAP                                          and Policy/
             )                                               Advocacy
                                                             Program
------------------------------------------------------------------------
Monetary    Nationa  444             $125,000    3/17/2014  Affordable
             l        North                                  Care Act
             Allian   Capitol                                (ACA),
             ce of    Street,                                Viral
             State    NW                                     Hepatitis,
             and      Suite                                  and Ryan
             Territ   339                                    White/ADAP
             orial    Washing                                Public
             AIDS     ton, DC                                Policy and
             Direct   20001                                  Technical
             ors                                             Assistance
                                                             Projects/
                                                             Charitable
                                                             Contributio
                                                             n
------------------------------------------------------------------------
Monetary    Nationa  444             $150,000   12/18/2014  2015
             l        North                                  Affordable
             Allian   Capitol                                Care Act
             ce of    Street,                                (ACA),
             State    NW                                     Viral
             and      Suite                                  Hepatitis,
             Territ   339                                    and Ryan
             orial    Washing                                White/ADAP
             AIDS     ton, DC
             Direct   20001
             ors
------------------------------------------------------------------------
Monetary    New      44 South          $5,000     8/7/2014  Community
             Jersey   Street,                                Based
             AIDS     Morrist                                Services
             Servic   own NJ
             es       07960
------------------------------------------------------------------------
Monetary    North    5 Center         $10,000     2/3/2014  Living Well
             Shore    Street                                 with
             Health   Glouces                                Hepatitis C
             Projec   ter, MA
             t,       01930
             Inc.
------------------------------------------------------------------------
Monetary    Nova     2946              $5,000    6/23/2014  En Direccion
             Salud    Sleepyh                                Positiva
                      ollow                                  Spanish-
                      Road                                   Speaking
                      Suite                                  HIV/AIDS
                      4A                                     Support
                      Falls                                  Group
                      Church,
                      VA
                      22044
------------------------------------------------------------------------
Monetary    OPAT     1192              $2,500    3/12/2014  Infectious
             Outcom   Smith                                  Disease
             es       Street                                 Hepatitis C
             Regist   Honolul                                Virus (HCV)
             ry       u, HI                                  Education,
                      96817                                  Screening,
                                                             Pre/Post
                                                             Education
                                                             and Linkage
                                                             to Care
                                                             2014-2015 /
                                                             Charitable
                                                             Contributio
                                                             n
------------------------------------------------------------------------
Monetary    Patient  421             $750,000   12/16/2014  Patient
             Advoca   Butler                                 Advocate
             te       Farm                                   Foundation'
             Founda   Road                                   s Co-Pay
             tion     Hampton                                Relief
                      , VA                                   (CPR)
                      23666                                  Program
                                                             Hepatitis C
                                                             Silo
------------------------------------------------------------------------
Monetary    Patient  421           $5,000,000    1/14/2014  Patient
             Advoca   Butler                                 Advocate
             te       Farm                                   Foundation'
             Founda   Road                                   s Co-Pay
             tion     Hampton                                Relief
                      , VA                                   (CPR)
                      23666                                  Program-
                                                             Hepatitis C
                                                             Silo
------------------------------------------------------------------------
Monetary    Philade  1233             $10,000     7/9/2014  2014 AIDS
             lphia    Locust                                 Education
             FIGHT    Street                                 Month
                      3rd
                      Floor
                      Philade
                      lphia,
                      PA
                      19107
------------------------------------------------------------------------
Monetary    Project  273              $25,000    6/25/2014  Think Tank
             Inform   Ninth                                  to Provide
                      Street                                 Technical
                      San                                    Assistance
                      Francis                                to Ten
                      co, CA                                 Jurisdictio
                      94103                                  ns on the
                                                             Use of HIV
                                                             Surveillanc
                                                             e to
                                                             Support
                                                             Linkage and
                                                             Retention
                                                             in Care and
                                                             Treatment
------------------------------------------------------------------------
Monetary    Project  273              $40,000     7/1/2014  The Support
             Inform   Ninth                                  Partnership
                      Street
                      San
                      Francis
                      co, CA
                      94103
------------------------------------------------------------------------
Monetary    Project  273              $40,000     7/4/2014  Mission
             Inform   Ninth                                  Support for
                      Street                                 Project
                      San                                    Inform /
                      Francis                                Charitable
                      co, CA                                 Contributio
                      94103                                  n
------------------------------------------------------------------------
Monetary    Project  273              $25,000   12/15/2014  Educational
             Inform   Ninth                                  and Policy
                      Street                                 Activities
                      San                                    to Support
                      Francis                                Hepatitis C
                      co, CA                                 Care
                      94103                                  Linkage
------------------------------------------------------------------------
Monetary    Project  2929 NE           $2,000    3/12/2014  Many Men,
             Link     6                                      Many Voices
             of       Avenue                                 (3MV) and
             South    Wilton                                 Many Women,
             Florid   Manors,                                Many Voices
             a,       FL                                     (3WV)
             Inc.     33334
------------------------------------------------------------------------
Monetary    Project  530 W             $5,000   11/13/2014  Transitional
             Transi   Street                                 Housing
             tions    Road
                      Warmins
                      ter, PA
                      18974
------------------------------------------------------------------------
Monetary    Provide  1150             $40,000     7/4/2014  Providence
             nce      Varnum                                 Hepatitis C
             Health   St. NE                                 Program
             Founda   Washing
             tion     ton, DC
                      20721
------------------------------------------------------------------------
Monetary    Ryan     1775 T           $10,000    4/25/2014  HEPATITIS:
             White    Street                                 Education,
             CARE     NW                                     Advocacy
             Act      Washing                                and
             Title    ton, DC                                Leadership
             II       20009                                  (HEAL)
             Commun
             ity
             AIDS
             Nation
             al
             Networ
             k (T
             II
             CANN)
------------------------------------------------------------------------
Monetary    San      1035             $30,000    8/25/2014  The
             Franci   Market                                 Stonewall
             sco      Street                                 Project
             AIDS     San
             Founda   Francis
             tion     co, CA
                      94103
------------------------------------------------------------------------
Monetary    Southwe  300               $5,000     3/1/2014  HIV Care in
             st       Southwe                                a Safety
             Boulev   st                                     Net Clinic/
             ard      Bouleva                                Charitable
             Family   rd                                     Contributio
             Health   Kansas                                 n
             Care,    City,
             Inc      KS
                      66103
------------------------------------------------------------------------
Monetary    Special  605 W             $5,000    1/28/2014  Asian
             Servic   Olympic                                Pacific
             e for    Bouleva                                AIDS
             Groups   rd                                     Interventio
             , Inc.   Suite                                  n Team
                      600 Los                                (APAIT)
                      Angeles                                Charitable
                      , CA                                   Contributio
                      90015                                  n
------------------------------------------------------------------------
Monetary    The      17 Davis         $60,000     3/5/2014  Florida
             AIDS     Bouleva                                Hepatitis
             Instit   rd                                     Education
             ute      Suite                                  and
                      403                                    Advocacy
                      Tampa,                                 Network
                      FL                                     (FHEAN) and
                      33606                                  health web
                                                             portal
                                                             (www.HepInf
                                                             oNow.org) /
                                                             Charitable
                                                             Contributio
                                                             n
------------------------------------------------------------------------
Monetary    The      17 Davis         $50,000     7/9/2014  Protecting
             AIDS     Bouleva                                and
             Instit   rd                                     enhancing
             ute      Suite                                  the
                      403                                    Hepatitis C
                      Tampa,                                 and the HIV/
                      FL                                     AIDS
                      33606                                  national
                                                             and state
                                                             programs
                                                             and
                                                             policies in
                                                             the U.S.
------------------------------------------------------------------------
Monetary    The      121              $40,000    4/18/2014  The SHE
             Fund     Avenue                                 Initiative
             for      of the
             the      America
             City     s 6th
             of New   Floor
             York     New
                      York,
                      NY
                      10013
------------------------------------------------------------------------
Monetary    The      330              $15,000    7/22/2014  The Well
             Well     Grace                                  Project's
             Projec   Glen                                   Online
             t        Nellysf                                Resources
                      ord, VA                                for Women
                      22958                                  and HIV
------------------------------------------------------------------------
Monetary    Tides    835              $20,000   11/25/2014  Website:
             Center   Solano                                 HCVAdvocate
                      Street
                      West
                      Sacrame
                      nto, CA
                      95605
------------------------------------------------------------------------
Monetary    TPA      5537 N           $20,000     7/9/2014  Total Care
             Networ   Broadwa                                Portal
             k        y
             Incorp   Chicago
             orated   , IL
             -Test    60640
             Positi
             ve
             Aware
             Networ
             k
------------------------------------------------------------------------
Monetary    Treatme  261 5th          $40,000    6/17/2014  Case Studies
             nt       Avenue                                 Project
             Action   Suite
             Group    2110
             (TAG)    New
                      York,
                      NY10016
------------------------------------------------------------------------
Monetary    Univers  c/o UC           $15,000     3/5/2014  ``Linkage To
             ity of   San                                    Care, After
             Califo   Diego                                  HIV
             rnia,    AIDS                                   Testing''/
             San      Researc                                Charitable
             Diego    h                                      Contributio
                      Institu                                n
                      te 9500
                      Gilman
                      Drive
                      #0716
                      La
                      Jolla,
                      CA
                      92093-
                      0716
------------------------------------------------------------------------
Monetary    Victory  965              $10,000     2/3/2014  Prevention,
             Progra   Massach                                Education,
             ms,      usetts                                 and Health
             Inc.     Avenue                                 Connections
                      Boston,                                Services
                      MA                                     for People
                      02118                                  with HIV/
                                                             AIDS.
------------------------------------------------------------------------
Monetary    VT       187               $5,000    3/13/2014  HIV Care and
             Commit   Saint                                  Support
             tee      Paul                                   Program
             For      Street                                 Across
             AIDS     Burling                                Vermont
             Resour   ton, VT
             ces      05401
             Educ
             and
             Servic
             es
------------------------------------------------------------------------
Monetary    Wright   8101              $5,000     3/3/2014  Case
             House    Cameron                                Management
             Wellne   Road                                   for HIV/HCV
             ss       Suite                                  Clients
             Center   105
                      Austin,
                      TX
                      78754
------------------------------------------------------------------------
Janssen has also made financial donations to independent charitable
  foundations that assist patients who are underinsured and in financial
  need with treatment-related expenses. In keeping with our donor
  agreements and applicable regulatory guidance, we will only disclose
  aggregate data on our charitable giving and do not publicize
  information on donations to specific foundations and disease states.
  In 2014, we contributed approximately $5.8 million in donations to
  independent charitable foundations, enabling them to provide
  assistance with medication-related copays to patients with infectious
  diseases.


----------------------------------------------------------------------------------------------------------------
 
----------------------------------------------------------------------------------------------------------------
Product               Johnson & Johnson     One Johnson &           $5,615,443    3/15/2013  Patient Assistance
                       Patient Assistance    Johnson Plaza, New                               Product Donation
                       Foundation            Brunswick, NJ 08933
----------------------------------------------------------------------------------------------------------------
Product               Johnson & Johnson     One Johnson &           $9,794,392    6/15/2013  Patient Assistance
                       Patient Assistance    Johnson Plaza, New                               Product Donation
                       Foundation            Brunswick, NJ 08933
----------------------------------------------------------------------------------------------------------------
Product               Johnson & Johnson     One Johnson &          $26,177,458    9/15/2013  Patient Assistance
                       Patient Assistance    Johnson Plaza, New                               Product Donation
                       Foundation            Brunswick, NJ 08933
----------------------------------------------------------------------------------------------------------------
Product               Johnson & Johnson     One Johnson &          $58,375,988   12/15/2013  Patient Assistance
                       Patient Assistance    Johnson Plaza, New                               Product Donation
                       Foundation            Brunswick, NJ 08933
----------------------------------------------------------------------------------------------------------------


 Janssen Biotech, Inc. Monetary and Product Contributions to U.S.-based
                Charitable Organizations Full Year 2015
  (Payments made from January 1, 2015 to December 31, 2015)--Amended on
                            February 24, 2017
------------------------------------------------------------------------
                                                               Project
 Donation    Payee     Payee   Payment Amount    Payment       Title/
   Type               Address       (USD)          Date     Description
------------------------------------------------------------------------
Monetary    100      4631              $2,000    7/17/2015  The 100
             Black    Delmar                                 Black Men
             Men of   St.                                    of
             Metrop   Louis,                                 Metropolita
             olitan   Missour                                n St. Louis
             St.      i 63108                                Community
             Louis                                           Health Day
                                                             Featuring
                                                             Prostate
                                                             Cancer Run/
                                                             Walk
------------------------------------------------------------------------
Monetary    100      4631              $1,800   12/23/2015  The 100
             Black    Delmar                                 Black Men
             Men of   St.                                    of
             Metrop   Louis,                                 Metropolita
             olitan   Missour                                n St. Louis
             St.      i 63108                                Community
             Louis                                           Health Day
                                                             Featuring
                                                             Prostate
                                                             Cancer Run/
                                                             Walk
------------------------------------------------------------------------
Monetary    Achieve  104               $5,625    12/4/2015  Achieve Now:
             Now      Gladsto                                Bringing
                      ne                                     Students Up
                      Street                                 to Grade
                      Philade                                Level
                      lphia,                                 Reading
                      PA
                      19148
------------------------------------------------------------------------
Monetary    America  Manasqua         $10,000     4/8/2015  Road To
             n        n, NJ                                  Recovery
             Cancer   08736                                  Program
             Societ
             y,
             Inc.
------------------------------------------------------------------------
Monetary    America  Manasqua          $1,000    5/27/2015  2015 Run for
             n        n, NJ                                  Dad
             Cancer   08736
             Societ
             y,
             Inc.
------------------------------------------------------------------------
Monetary    America  1626              $1,000     7/8/2015  American
             n        Locust                                 Cancer
             Cancer   Street                                 Society,
             Societ   Philade                                Relay For
             y,       lphia,                                 Life of the
             Inc.     PA                                     Wissahickon
                      19103                                  Valley,
                                                             Ambler, PA
------------------------------------------------------------------------
Monetary    Arthrit  National        $225,000     6/5/2015  Sponsorship
             is       Office                                 of 117
             Founda   1330 W.                                Jingle Bell
             tion     Peachtr                                Run events,
                      ee St.,                                reaching
                      N.W.                                   more than
                      Atlanta                                100,000
                      , GA                                   participant
                      30309                                  s and
                                                             volunteers,
                                                             across the
                                                             country
------------------------------------------------------------------------
Monetary    Arthrit  1817              $2,000     6/4/2015  The
             is       Central                                Community
             Servic   Avenue                                 Arthritis
             es       Suite                                  Project of
                      211                                    Charlotte,
                      Charlot                                Mecklenburg
                      te, NC                                 County,
                      28205                                  North
                                                             Carolina
------------------------------------------------------------------------
Monetary    Cancer   275               $2,000     7/3/2015  Seventh
             Care,    Seventh                                Annual
             Inc.     Avenue                                 Healing
                      New                                    Hearts
                      York,                                  Family
                      NY                                     Bereavement
                      10001                                  Camp
                                                             Milford, PA
------------------------------------------------------------------------
Monetary    Cancer   3                 $5,000    12/2/2015  Oncology
             Suppor   Crossro                                Support
             t        ads                                    Groups
             Commun   Drive
             ity      Bedmins
             Centra   ter, NJ
             l New    07921
             Jersey
------------------------------------------------------------------------
Monetary    Cancer   200 Kirk          $1,000    7/10/2015  Paws 4 Life
             Suppor   Road PO                                Dog Walk,
             t        Box                                    Warminster
             Commun   3187                                   PA
             ity of   Warmins
             Philad   ter, PA
             elphia   18974
             (forme
             rly
             Gilda'
             s Club
             Bucks/
             Mont
             Counti
             es)
------------------------------------------------------------------------
Monetary    Cancer   200 Kirk          $2,500   10/23/2015  Celebration
             Suppor   Road PO                                of Hope: A
             t        Box                                    Free, Full-
             Commun   3187                                   Day,
             ity of   Warmins                                Educational
             Philad   ter, PA                                and
             elphia   18974                                  Inspiration
             (forme                                          al
             rly                                             Conference
             Gilda'                                          for Greater
             s Club                                          Philadelphi
             Bucks/                                          a-Area
             Mont                                            Cancer
             Counti                                          Patients,
             es)                                             Survivors,
                                                             and
                                                             Caregivers
------------------------------------------------------------------------
Monetary    Center   1900              $2,000     7/9/2015  Project for
             for      Cherry                                 Medically
             Child    Street                                 Needy
             Advoca   Philade                                Children
             tes      lphia,
                      PA
                      19103
------------------------------------------------------------------------
Monetary    Childre  6380              $7,500    3/17/2015  Children's
             ns       Flank                                  Cancer
             Cancer   Drive,                                 Recovery
             Recove   Suite                                  Foundation'
             ry       400                                    s Bear-Able
             Founda   Harrisb                                Gift
             tion     urg, PA                                Program:
                      17112                                  administere
                                                             d to the
                                                             Children's
                                                             Hospital of
                                                             Philadelphi
                                                             a
------------------------------------------------------------------------
Monetary    Childre  6380              $7,500   12/22/2015  Bear-Able
             ns       Flank                                  Gifts
             Cancer   Drive,                                 program
             Recove   Suite
             ry       400
             Founda   Harrisb
             tion     urg, PA
                      17112
------------------------------------------------------------------------
Monetary    Childre  The               $1,000   12/23/2015  General
             n's      Childre                                Operating
             Hospit   n's                                    Support for
             al of    Hospita                                The Center
             Philad   l of                                   for
             elphia   Philade                                Pediatric
             Founda   lphia                                  Inflammator
             tion     Foundat                                y Bowel
                      ion                                    Disease
                      Attn:
                      Staci
                      Carney,
                      Associa
                      te
                      Directo
                      r,
                      Corpora
                      te and
                      Foundat
                      ion
                      Relatio
                      ns 100
                      Penn
                      Square
                      East
                      8th
                      Floor,
                      Suite
                      8050
                      Philade
                      lphia,
                      PA
                      19107
------------------------------------------------------------------------
Monetary    Childre  The              $12,000     4/8/2016  Family Care
             n's      Childre                                Binder
             Hospit   n's                                    Program at
             al of    Hospita                                The
             Philad   l of                                   Children's
             elphia   Philade                                Hospital of
             Founda   lphia                                  Philadelphi
             tion     Foundat                                a
                      ion                                    Philadelphi
                      Attn:                                  a, PA
                      Staci
                      Carney,
                      Associa
                      te
                      Directo
                      r,
                      Corpora
                      te and
                      Foundat
                      ion
                      Relatio
                      ns 100
                      Penn
                      Square
                      East
                      8th
                      Floor,
                      Suite
                      8050
                      Philade
                      lphia,
                      PA
                      19107
------------------------------------------------------------------------
Monetary    Childre  The               $6,000     4/8/2016  6th Annual
             n's      Childre                                Walk for
             Hospit   n's                                    Hope
             al of    Hospita                                benefiting
             Philad   l of                                   IBD
             elphia   Philade                                research at
             Founda   lphia                                  The
             tion     Foundat                                Children's
                      ion                                    Hospital of
                      Attn:                                  Philadelphi
                      Staci                                  a, Veterans
                      Carney,                                Park,
                      Associa                                Hamilton,
                      te                                     NJ
                      Directo
                      r,
                      Corpora
                      te and
                      Foundat
                      ion
                      Relatio
                      ns 100
                      Penn
                      Square
                      East
                      8th
                      Floor,
                      Suite
                      8050
                      Philade
                      lphia,
                      PA
                      19107
------------------------------------------------------------------------
Monetary    Communi  300B             $20,000    12/8/2015  Free Medical
             ty       Lawrenc                                and Dental
             Volunt   e Drive                                Care to
             eers     West                                   Uninsured,
             in       Chester                                Low-Income
             Medici   , PA                                   Individuals
             ne       19380                                  and
                                                             Families
                                                             Who Live or
                                                             Work in
                                                             Chester
                                                             County.
                                                             Community
                                                             Volunteers
                                                             in Medicine
                                                             is located
                                                             in West
                                                             Chester, PA
------------------------------------------------------------------------
Monetary    Crohns   733             $135,000     6/5/2015  CCFA Take
             and      Third                                  Steps Walk/
             Coliti   Avenue                                 Run
             s        Suite
             Founda   510 New
             tion     York,
             of       NY
             Americ   10017
             a
------------------------------------------------------------------------
Monetary    Crohn's  733              $18,000     7/7/2015  Camp Oasis--
             and      Third                                  Program is
             Coliti   Avenue                                 hosted at
             s        Suite                                  12 campsite
             Founda   510 New                                locations
             tion     York,                                  across the
             of       NY                                     country
             Americ   10017
             a,
             Inc.
------------------------------------------------------------------------
Monetary    Delawar  236              $21,500    3/20/2015  Delaware
             e        Randell                                Valley
             Valley   Hall                                   Science
             Scienc   3141                                   Fairs
             e        Chestnu                                Philadelphi
             Fairs,   t                                      a, PA
             Inc.     Street
                      Philade
                      lphia,
                      PA
                      19104
------------------------------------------------------------------------
Monetary    Family   2001            $250,000   12/21/2015  Family Reach
             Reach    Route                                  Programmati
             Founda   46,                                    c Support
             tion     Suite
                      310
                      Parsipp
                      any, NJ
                      07054
------------------------------------------------------------------------
Monetary    Family   2001             $20,000   12/21/2015  Family Reach
             Reach    Route                                  Foundation
             Founda   46,                                    General
             tion     Suite                                  Support
                      310
                      Parsipp
                      any, NJ
                      07054
------------------------------------------------------------------------
Monetary    Friends  113 West          $3,000   12/14/2015  Homelessness
             Associ   Chestnu                                to
             ation    t                                      Independenc
             For      Street                                 e
             Care     West                                   Initiative
             and      Chester
             Protec   , PA
             tion     19380
             Of
             Childr
             en
------------------------------------------------------------------------
Monetary    Friends  815 West            $825    9/23/2015  Employee
             of the   7th                                    directed
             Queen    Street                                 donation in
             City     Plainfi                                Lieu of
             Academ   eld, NJ                                holiday
             y        07063                                  gift
             Charte
             r
             School
------------------------------------------------------------------------
Monetary    Georgia  Alpharet          $1,500    8/12/2015  Georgia
             Prosta   ta, GA                                 Prostate
             te       30022                                  Cancer Free
             Cancer                                          Screening
             Coalit                                          Event
             ion,
             Inc.
------------------------------------------------------------------------
Monetary    Georgia  Alpharet          $1,700   12/23/2015  Georgia
             Prosta   ta, GA                                 Prostate
             te       30022                                  Cancer Free
             Cancer                                          Screening
             Coalit                                          Event
             ion,
             Inc.
------------------------------------------------------------------------
Monetary    Girl     330               $3,000   12/14/2015  GSEP STEM
             Scouts   Manor                                  Programming
             of       Road
             Southe   Miquon,
             astern   PA
             Pennsy   19444
             lvania
------------------------------------------------------------------------
Monetary    Girl     501 S.            $1,250    5/27/2015  16th Annual
             Scouts   College                                Women of
             of the   Avenue                                 Distinction
             Chesap   Newark,                                Program and
             eake     DE                                     Celebration
             Bay      19713
             Counci
             l,
             Inc.
------------------------------------------------------------------------
Monetary    Great    PO Box            $5,000   12/14/2015  GVNC
             Valley   82 4251                                Environment
             Nature   State                                  al
             Center   Road                                   Education
                      Devault                                Programs
                      , PA                                   with
                      19432                                  Schools-
                                                             Water
                                                             Quality,
                                                             Pond,
                                                             Stream and
                                                             Habitat
                                                             Study
------------------------------------------------------------------------
Monetary    Green    1368             $15,000    12/8/2015  Watershed
             Valley   Prizer                                 Education
             s        Road                                   Programs
             Associ   Pottsto
             ation    wn, PA
                      19465
------------------------------------------------------------------------
Monetary    Habitat  P.O. Box          $1,000   10/27/2015  Habitat for
             for      1452                                   Humanity of
             Humani   621                                    Chester
             ty of    Lumber                                 County
             Cheste   Street
             r        Coatesv
             County   ille,
             , Inc.   PA
                      19320
------------------------------------------------------------------------
Monetary    Habitat  1829 N.           $5,000   12/14/2015  Habitat for
             For      19th                                   Humanity
             Humani   Street                                 Philadelphi
             ty       Philade                                a
             Philad   lphia,                                 Homeownersh
             elphia   PA                                     ip Program
             , Inc.   19121
------------------------------------------------------------------------
Monetary    Hatboro- 229              $25,000    12/2/2015  STEM
             Horsha   Meeting                                Programs
             m        house                                  for Hatboro-
             Educat   Road                                   Horsham
             ional    Horsham                                Students
             Founda   , PA
             tion     19044
------------------------------------------------------------------------
Monetary    Hope     129                 $300    9/21/2015  Costs
             for      Yerger                                 associated
             Kids,    Road                                   with 2015
             Inc.     Schwenk                                Janssen
                      sville,                                Cares
                      PA                                     Volunteer
                      19473                                  Activity
------------------------------------------------------------------------
Monetary    Kids     26071             $3,000     9/4/2015  Support
             Connec   Merit                                  Groups for
             ted      Circle,                                Children of
                      #103                                   Cancer
                      Laguna                                 Patients
                      Hills,                                 Costa Mesa,
                      CA                                     Ca Brea, Ca
                      92653-                                 Santa Ana,
                      7016                                   Ca Laguna
                                                             Hills, Ca
                                                             La Jolla,
                                                             Ca
                                                             Temecula,
                                                             Ca
------------------------------------------------------------------------
Monetary    Metropo  2323             $20,000    12/7/2015  Medically
             litan    Ranstea                                Appropriate
             Area     d                                      Meals for
             Neighb   Street                                 People with
             orhood   Philade                                Critical
             Nutrit   lphia,                                 Illnesses
             ion      PA
             Allian   19103
             ce
             (MANNA
             )
------------------------------------------------------------------------
Monetary    Montgom  340              $10,000   12/15/2015  Bridge to
             ery      DeKalb                                 Employment
             County   Pike                                   Program
             Commun   Blue                                   Enhancement
             ity      Bell,                                  through
             Colleg   PA                                     Strategies
             e        19422                                  for Success
             Founda
             tion
------------------------------------------------------------------------
Monetary    Movembe  Culver            $5,000    5/22/2015  Movember is
             r        City,                                  a national
             Founda   CA                                     US campaign
             tion     90232                                  where we
                                                             ask men to
                                                             grow
                                                             moustaches
                                                             to raise
                                                             awareness
                                                             and funds
                                                             for men's
                                                             health
------------------------------------------------------------------------
Monetary    Multipl  51 Locus          $5,000    7/10/2015  2015 MMRF
             e        Avenue                                 Team for
             Myelom   Suite                                  Cures: New
             a        201                                    York City
             Resear   Norwalk                                5K Walk/Run
             ch       , CT
             Founda   06851
             tion
------------------------------------------------------------------------
Monetary    Multipl  51 Locus          $5,000    7/10/2015  2015 MMRF
             e        Avenue                                 Team for
             Myelom   Suite                                  Cures:
             a        201                                    Philadelphi
             Resear   Norwalk                                a 5K Walk/
             ch       , CT                                   Run
             Founda   06851
             tion
------------------------------------------------------------------------
Monetary    Multipl  383 Main         $10,000    7/13/2015  MMRF Team
             e        Avenue                                 for Cures
             Myelom   5th                                    Sponsor--NY
             a        Floor                                  C Marathon,
             Resear   Norwalk                                (NY, NY)
             ch       , CT                                   and Fenway
             Founda   06851                                  Spartan
             tion                                            Race
                                                             (Boston, MA
                                                             )
------------------------------------------------------------------------
Monetary    Nationa  4719              $2,500     4/8/2015  17th Annual
             l        Reed                                   Break the
             Ovaria   Road                                   Silence on
             n        #150                                   Ovarian
             Cancer   Holicon                                Cancer
             Coalit   g, PA                                  Philadelphi
             ion--C   18928                                  a, PA
             entral
             Ohio
             Chapte
             r
------------------------------------------------------------------------
Monetary    Nationa  6600 SW          $75,000    4/14/2015  2015 Team
             l        02nd                                   NPF Walk--
             Psoria   Avenue,                                National
             sis      Ste.                                   (19 U.S.
             Founda   300                                    cities)
             tion     Portlan
                      d, OR
                      97223
------------------------------------------------------------------------
Monetary    Pennypa  7005                $300    9/21/2015  Costs
             ck       Sheaff                                 associated
             Farm     Lane                                   with 2015
             and      Fort                                   Janssen
             Educat   Washing                                Cares
             ion      ton, PA                                Volunteer
             Center   19034                                  Activity
------------------------------------------------------------------------
Monetary    Project  1515              $1,000    12/2/2015  Mental
             HOME     Fairmou                                Health and
                      nt                                     Recovery
                      Avenue                                 Services
                      Philade                                for
                      lphia,                                 Individuals
                      PA                                     Who Have
                      19130                                  Experienced
                                                             Homelessnes
                                                             s
------------------------------------------------------------------------
Monetary    Prostat  7009 S.          $30,000    7/13/2015  Prostate
             e        Potomac                                Cancer
             Cancer   Street                                 Disparities
             Educat   Suite                                  Outreach
             ion      125                                    Program--A
             Counci   Centenn                                national,
             l        ial, CO                                ten city
                      80112                                  event
------------------------------------------------------------------------
Monetary    Prostat  7009 S.          $20,000   12/23/2015  Prostate
             e        Potomac                                Cancer
             Cancer   Street                                 Disparities
             Educat   Suite                                  Outreach
             ion      125                                    Program--A
             Counci   Centenn                                national,
             l        ial, CO                                ten city
                      80112                                  event
------------------------------------------------------------------------
Monetary    Rebuild  P.O. Box          $6,000    3/17/2015  House Build
             ing      42752
             Togeth   Philade
             er       lphia,
             Philad   PA
             elphia   19101-
                      2752
------------------------------------------------------------------------
Monetary    Retired  925              $10,000    3/20/2015  RSVP's My
             and      Harvest                                Free Tutor
             Senior   Drive,                                 (MFT) and
             Volunt   Suite                                  Family
             eer      100                                    Literacy
             Progra   Blue                                   Volunteer
             m of     Bell,                                  Program
             Montgo   PA                                     (FLVP)
             mery     19422
             County
------------------------------------------------------------------------
Monetary    Retired  925               $5,000     7/9/2015  RSVP's
             and      Harvest                                Protege and
             Senior   Drive,                                 America
             Volunt   Suite                                  Reads/
             eer      100                                    Writes
             Progra   Blue                                   Programs
             m of     Bell,
             Montgo   PA
             mery     19422
             County
------------------------------------------------------------------------
Monetary    Retired  925              $10,000    12/7/2015  RSVP's
             and      Harvest                                Family
             Senior   Drive,                                 Literacy
             Volunt   Suite                                  Volunteer
             eer      100                                    Program
             Progra   Blue                                   (FLVP) and
             m of     Bell,                                  My Free
             Montgo   PA                                     Tutor (MFT)
             mery     19422                                  virtual
             County                                          STEM
                                                             tutoring
                                                             and career
                                                             awareness
                                                             program.
------------------------------------------------------------------------
Monetary    Riverbe  1950              $6,000     7/3/2015  Outreach to
             nd       Spring                                 Children/
             Enviro   Mill                                   Access to
             nmenta   Road                                   Nature
             l        Gladwyn                                (Norristown
             Educat   e, PA                                  , PA)
             ion      19035
             Center
------------------------------------------------------------------------
Monetary    Sandy    2010              $2,000    5/15/2015  11th Annual
             Rollma   West                                   Sandy
             n        Chester                                Sprint 5K/
             Ovaria   Pike                                   10K Run/
             n        Suite                                  Walk
             Cancer   300
             Founda   Haverto
             tion,    wn, PA
             Inc.     19083
------------------------------------------------------------------------
Monetary    Senior   536                 $500    8/12/2015  2015 Meals
             Adult    George                                 On Wheels
             Activi   St.                                    Outrunning
             ties     Norrist                                Senior
             Center   own, PA                                Hunger 5k/
             of       19401                                  3k. Mont Co
             Montgo                                          Comm
             mery                                            College,
             County                                          Blue Bell,
                                                             PA. Meals
                                                             On Wheels
                                                             of the
                                                             Senior
                                                             Adult
                                                             Activities
                                                             Center of
                                                             Montgomery
                                                             County
                                                             impacts
                                                             homebound
                                                             seniors in
                                                             Central,
                                                             North Penn
                                                             and the
                                                             Eastern
                                                             Montgomery
                                                             Co areas.
------------------------------------------------------------------------
Monetary    Senior   536                 $300    8/20/2015  Costs
             Adult    George                                 associated
             Activi   St.                                    with 2015
             ties     Norrist                                Janssen
             Center   own, PA                                Cares
             of       19401                                  Volunteer
             Montgo                                          Activity
             mery
             County
------------------------------------------------------------------------
Monetary    Special  2800                $300    8/20/2015  Costs
             Equest   Street                                 associated
             rians    Road                                   with 2015
                      P.O.                                   Janssen
                      Box                                    Cares
                      1001                                   Volunteer
                      Warring                                Activity
                      ton, PA
                      18976
------------------------------------------------------------------------
Monetary    Special  2800              $4,000    9/23/2015  Special
             Equest   Street                                 Equestrians
             rians    Road                                   Equine
                      P.O.                                   Assisted
                      Box                                    Learning
                      1001                                   and
                      Warring                                Therapeutic
                      ton, PA                                Riding
                      18976                                  Program
                                                             Warrington,
                                                             PA
------------------------------------------------------------------------
Monetary    Starfin  4015             $10,000    3/20/2015  Youth
             der      Main                                   Development
             Founda   Street                                 through
             tion     Philade                                Soccer and
                      lphia,                                 Education
                      PA                                     Philadelphi
                      19127                                  a, PA
------------------------------------------------------------------------
Monetary    Stop     2501             $40,700    5/22/2015  Janssen
             Hunger   Clark                                  Biotech and
             Now      Street,                                Stop Hunger
                      Suite                                  Now Engage
                      301                                    Employee
                      Raleigh                                Volunteers
                      , NC                                   in Dallas,
                      27607                                  Texas
------------------------------------------------------------------------
Monetary    The      222              $10,000   11/26/2015  Corporate
             Frankl   North                                  Membership
             in       20th
             Instit   Street
             ute      Philade
                      lphia,
                      PA
                      19103
------------------------------------------------------------------------
Monetary    The      Gwynedd           $3,000     7/3/2015  General
             Giving   Valley,                                Operating
             Tree     PA                                     Support
                      19437
------------------------------------------------------------------------
Monetary    The      2600             $10,000     4/8/2015  Hubert J.P.
             Melmar   Wayland                                Schoemaker
             k        Road                                   Classic
             Charit   Berwyn,
             able     PA
             Founda   19312
             tion
------------------------------------------------------------------------
Monetary    The      2600                $300    8/21/2015  Costs
             Melmar   Wayland                                associated
             k        Road                                   with 2015
             Charit   Berwyn,                                Janssen
             able     PA                                     Cares
             Founda   19312                                  Volunteer
             tion                                            Activity
------------------------------------------------------------------------
Monetary    The      400                 $300    8/20/2015  Costs
             Pennsb   Pennsbu                                associated
             ury      ry                                     with 2015
             Societ   Memoria                                Janssen
             y        l Road                                 Cares
                      Morrisv                                Volunteer
                      ille,                                  Activity
                      PA
                      19067
------------------------------------------------------------------------
Monetary    Trustee  3025              $5,000   12/23/2015  WXPN
             s Of     Walnut                                 Musicians
             The      Street                                 On Call
             Univer   Philade
             sity     lphia,
             Of       PA
             Pennsy   19104
             lvania
------------------------------------------------------------------------
Monetary    United   1709            $260,045   12/23/2015  United Way
             Way of   Benjami                                Campaign
             Southe   n                                      Match
             astern   Frankli
             Pennsy   n
             lvania   Parkway
                      Philade
                      lphia,
                      PA
                      19103
------------------------------------------------------------------------
Monetary    Us Too   5003              $1,000     4/8/2015  11th Annual
             Intern   Fairvie                                SEA Blue
             ationa   w Ave.                                 Prostate
             l,       Downers                                Cancer 5K
             Inc.     Grove,                                 Run and
                      IL                                     Celebration
                      60515                                  Walk in
                                                             Chicago, IL
------------------------------------------------------------------------
Monetary    Zero     515 King         $75,000     4/8/2015  ZERO
             The      Street,                                Prostate
             Projec   Suite                                  Cancer Run/
             t To     420                                    Walk Series
             End      Alexand                                40-plus
             Prosta   ria, VA                                cities
             te       22314                                  nationwide
             Cancer                                          running
                                                             from March
                                                             to November
                                                             2015
------------------------------------------------------------------------
Monetary    Zero     515 King          $8,000   10/23/2015  ZERO
             The      Street,                                Baltimore
             Projec   Suite                                  Free
             t To     420                                    Prostate
             End      Alexand                                Cancer
             Prosta   ria, VA                                Screening
             te       22314                                  Program
             Cancer
------------------------------------------------------------------------
Janssen has also made financial donations to independent charitable
  foundations that assist patients who are underinsured and in financial
  need with treatment-related expenses. In keeping with our donor
  agreements and applicable regulatory guidance, we will only disclose
  aggregate data on our charitable giving and do not publicize
  information on donations to specific foundations and disease states.
  In 2015, we contributed $29.5 million in donations to independent
  charitable foundations, enabling them to provide assistance with
  medication-related copays to patients with cancer and autoimmune
  diseases.


----------------------------------------------------------------------------------------------------------------
 
----------------------------------------------------------------------------------------------------------------
Product               Johnson & Johnson     One Johnson &          $87,940,000    3/15/2015  Patient Assistance
                       Patient Assistance    Johnson Plaza, New                               Product Donation
                       Foundation            Brunswick, NJ 08933
----------------------------------------------------------------------------------------------------------------
Product               Johnson & Johnson     One Johnson &          $69,856,000    6/15/2015  Patient Assistance
                       Patient Assistance    Johnson Plaza, New                               Product Donation
                       Foundation            Brunswick, NJ 08933
----------------------------------------------------------------------------------------------------------------
Product               Johnson & Johnson     One Johnson &          $60,259,000    9/15/2015  Patient Assistance
                       Patient Assistance    Johnson Plaza, New                               Product Donation
                       Foundation            Brunswick, NJ 08933
----------------------------------------------------------------------------------------------------------------
Product               Johnson & Johnson     One Johnson &          $70,842,000   12/15/2015  Patient Assistance
                       Patient Assistance    Johnson Plaza, New                               Product Donation
                       Foundation            Brunswick, NJ 08933
----------------------------------------------------------------------------------------------------------------
Updated February 24, 2017


Janssen Pharmaceuticals, Inc. Monetary and Product Contributions to U.S.-
              based Charitable Organizations Full Year 2015
        (Payments made from January 1, 2015 to December 31, 2015)
------------------------------------------------------------------------
                                                               Project
 Donation    Payee     Payee   Payment Amount    Payment       Title/
   Type               Address       (USD)          Date     Description
------------------------------------------------------------------------
Monetary    180      1                 $1,000    11/3/2015  Youth
             Turnin   Bethany                                Helpline
             g        Road,
             Lives    Buildin
             Around   g 3,
             , Inc.   Suite
                      42
                      Hazlet,
                      NJ
                      07730
------------------------------------------------------------------------
Monetary    Adult    872. E.             $600    8/20/2015  Costs
             Day      Main                                   associated
             Center   Street                                 with 2015
             of       Bridgew                                Janssen
             Somers   ater,                                  Cares
             et       NJ                                     Volunteer
             County   08807                                  Activity
------------------------------------------------------------------------
Monetary    Advanci  1005              $2,500   10/23/2015  College
             ng       Whitehe                                Aspire and
             Opport   ad Road                                Inquire
             unitie   Extensi                                Program
             s,       on,
             Inc.     Suite 1
                      Ewing,
                      NJ
                      08520
------------------------------------------------------------------------
Monetary    Allies,  1262              $7,500   11/16/2015  Project Grow-
             Inc.     Whiteho                                Allies Farm
                      rse-                                   Program
                      Hamilto                                located on
                      n                                      the Grounds
                      Square                                 of Mercer
                      Road                                   County
                      Buildin                                Community
                      g A,                                   College,
                      Suite                                  West
                      101                                    Windsor, NJ
                      Hamilto
                      n, NJ
                      08690
------------------------------------------------------------------------
Monetary    America  6500                $600    1/22/2015  Employee
             n        Sugarlo                                directed
             Cancer   af                                     donation in
             Societ   Parkway                                lieu of
             y        , Suite                                company
                      260                                    holiday
                      Duluth,                                gift
                      GA
                      30097
------------------------------------------------------------------------
Monetary    America  Buffalo             $100    3/12/2015  Memorial
             n        Hope                                   donation
             Cancer   Lodge
             Societ   197
             y        Summer
                      Street
                      Buffalo
                      , NY
                      14222
------------------------------------------------------------------------
Monetary    America  1160             $30,000   10/29/2015  Diabetes
             n        Route                                  Interventio
             Diabet   22 East                                n Project
             es       Suite                                  ($30K) and
             Associ   103                                    the General
             ation    Bridege                                Education
                      water,                                 Outreach
                      NJ                                     ($10K)
                      08807
------------------------------------------------------------------------
Monetary    America  1701            $125,000    12/8/2015  American
             n        North                                  Diabetes
             Diabet   Beaureg                                Association
             es       ard                                    's What Can
             Associ   Street                                 I Eat?
             ation,   Alexand                                Choices for
             Inc.     ria, VA                                People with
                      22311                                  Type 2
                                                             Diabetes
------------------------------------------------------------------------
Monetary    America  1392 CR          $30,000   12/23/2015  Atrial
             n        2740,                                  Fibrillatio
             Founda   Decatur                                n Patient
             tion     , TX                                   Education
             For      76234-                                 and Support
             Womens   7401
             Health
------------------------------------------------------------------------
Monetary    America  7272             $10,000    12/8/2015  Garden State
             n        Greenvi                                Go Red For
             Heart    lle                                    Women
                      Avenue                                 Luncheon
                      Dallas,
                      TX
                      75231
------------------------------------------------------------------------
Monetary    America  1000            $210,000   12/17/2015  Judges'
             n        Wilson                                 Leadership
             Psychi   Blvd,                                  Initiative-
             atric    Suite                                  Psychiatric
             Founda   1825                                   Leadership
             tion     Arlingt                                for
                      on, VA                                 Criminal
                      22209                                  Justice
                                                             (JLI/PLCJ)
------------------------------------------------------------------------
Monetary    America  1000             $35,000   12/17/2015  Partnership
             n        Wilson                                 for
             Psychi   Blvd,                                  Workplace
             atric    Suite                                  Mental
             Founda   1825                                   Health
             tion     Arlingt
                      on, VA
                      22209
------------------------------------------------------------------------
Monetary    America  1000            $100,000   12/17/2015  Typical or
             n        Wilson                                 Troubled?
             Psychi   Blvd,                                  Student
             atric    Suite                                  Mental
             Founda   1825                                   Health
             tion     Arlingt                                Education
                      on, VA                                 Program
                      22209
------------------------------------------------------------------------
Monetary    America  707              $94,250   12/17/2015  Effort to
             n Red    Alexand                                support
             Cross    er Road                                disaster
                      Princet                                relief
                      on, NJ                                 american
                      08550                                  military
                                                             families,
                                                             health and
                                                             safety
                                                             services,
                                                             internation
                                                             al aid, and
                                                             blood
                                                             donation
                                                             services
                                                             within
                                                             central New
                                                             Jersey and
                                                             across the
                                                             US
------------------------------------------------------------------------
Monetary    AmeriCa  88                $4,600    12/8/2015  General
             res      Hamilto                                mission
             Founda   n Ave                                  support
             tion     Stamfor
                      d, CT
                      06902
------------------------------------------------------------------------
Monetary    Anchor   482                 $812    4/16/2015  General
             House,   Centre                                 Operating
             Inc.     Street                                 Support
                      Trenton
                      , NJ
                      08611
------------------------------------------------------------------------
Monetary    Anderso  PO Box              $300    8/19/2015  Costs
             n        134 532                                associated
             House    Route                                  with 2015
                      523                                    Janssen
                      Whiteho                                Cares
                      use                                    Volunteer
                      Station                                Activity
                      , NJ
                      08889
------------------------------------------------------------------------
Monetary    Anderso  532              $19,000    12/3/2015  Integrated
             n        County                                 Care
             House    Road                                   Management
                      523
                      P.O.
                      Box 134
                      Whiteho
                      use
                      Station
                      , NJ
                      08889
------------------------------------------------------------------------
Monetary    Ann      595 West          $9,500   11/12/2015  Ann
             Silver   State                                  Silverman
             man      Street                                 Community
             Commun   Doylest                                Health
             ity      own, PA                                Clinic for
             Health   18901                                  Bucks
             Clinic                                          County
                                                             residents
------------------------------------------------------------------------
Monetary    Arc      141               $3,500    11/2/2015  Fundraising
             Founda   South                                  event
             tion     Main                                   support to
             Of       Street                                 benefit
             Somers   Manvill                                general
             et       e, NJ                                  mission of
             County   08835                                  organizatio
             , Inc.                                          n
------------------------------------------------------------------------
Monetary    Associa  819               $9,000   11/16/2015  Partial Care
             tion     Alexand                                Day
             for      er Road                                Treatment,
             Advanc   Princet                                Physical
             ement    on, NJ                                 Health
             of       08540                                  Expansion
             Mental
             Health
------------------------------------------------------------------------
Monetary    Athens   7 N.              $1,000     7/1/2015  Mental
             Mental   Congres                                Health
             Health   s St.                                  Awarenss
             , Inc.   Athens,                                Event: 2nd
                      OH                                     Annual
                      45701                                  Community
                                                             Illuminatio
                                                             n
------------------------------------------------------------------------
Monetary    Autism   1060              $1,000   11/16/2015  Autism
             Speaks   State                                  Resource
                      Road                                   Fair
                      2nd                                    Sponsor
                      Floor                                  2016
                      Princet                                Central NJ
                      on, NJ                                 Walk Now
                      08540                                  for Autism
                                                             Speaks
------------------------------------------------------------------------
Monetary    Bay      66 Canal          $5,000    6/22/2015  Bay Cove
             Cove     St                                     Wellness
             Human    Boston,                                Center to
             Servic   MA                                     assist
             es,      02114                                  diverse low-
             Inc.                                            income
                                                             clients who
                                                             are working
                                                             towards
                                                             recovery
                                                             from severe
                                                             mental
                                                             illness
------------------------------------------------------------------------
Monetary    Bentley  PO Box              $300    8/11/2015  Costs
             Commun   1093                                   associated
             ity      Belle                                  with 2015
             Servic   Mead,                                  Janssen
             es,      NJ                                     Cares
             Inc.     08502                                  Volunteer
                                                             Activity
------------------------------------------------------------------------
Monetary    Big      2875              $6,500   11/16/2015  The STEM
             Brothe   York                                   School
             rs Big   Road                                   Mentoring
             Sister   Jamison                                program
             s of     , PA                                   (Centennial
             Bucks    18966                                  , Bensalem,
             County                                          Bristol
                                                             Township,
                                                             and
                                                             Pennsbury
                                                             school
                                                             districts
                                                             in Bucks
                                                             County, PA)
------------------------------------------------------------------------
Monetary    Big      2 West            $7,500   10/13/2015  Big Brothers
             Brothe   Washing                                Big Sisters
             rs Big   ton                                    of
             Sister   Avenue,                                Hunterdon
             s of     Suite                                  Somerset
             Hunter   210 PO                                 and Warren
             don      Box 123
             Somers   Washing
             et and   ton, NJ
             Warren   07882
             Counti
             es
------------------------------------------------------------------------
Monetary    Big      535 East          $6,500    9/28/2015  Youth
             Brothe   Frankli                                Mentoring
             rs Big   n                                      Program
             Sister   Street                                 Support
             s of     Trenton
             Mercer   , NJ
             County   08610
------------------------------------------------------------------------
Monetary    Boys     212              $22,500    12/8/2015  Career
             and      Centre                                 Launch
             Girls    Street
             Club     Trenton
             of       , NJ
             Trento   08611
             n and
             Mercer
             County
------------------------------------------------------------------------
Monetary    Bristol  120               $7,500   11/12/2015  ArtRageous
             Rivers   Radclif                                Theatre
             ide      fe                                     Arts
             Theate   Street                                 Education
             r Co,    Bristol                                Program
             Inc.     , PA
                      19007
------------------------------------------------------------------------
Monetary    Broward  305 SE           $12,500    7/21/2015  Affordable
             County   18th                                   Rental
             Commun   Court                                  Housing
             ity      Fort                                   program
             Develo   Lauderd
             pment    ale, FL
             Corpor   33316
             ation,
             Inc.
------------------------------------------------------------------------
Monetary    Bucks    1069              $5,000   11/16/2015  Bucks County
             County   Jackson                                Veterans
             Housin   ville                                  Housing
             g        Road                                   Assistance
             Group    Ivyland                                Program
                      , PA
                      18974
------------------------------------------------------------------------
Monetary    Caminar  2600 S.           $2,500     4/9/2015  First Annual
                      El                                     Mental
                      Camino                                 Health
                      Real,                                  Symposium:
                      Suite                                  New
                      200 San                                Research in
                      Mateo,                                 Mental
                      CA                                     Health and
                      94403                                  its Impact
                                                             on
                                                             Treatment
------------------------------------------------------------------------
Monetary    Camp     P.O. Box         $10,000   12/11/2015  Camp Odayin--
             Odayin   2068                                   a camp with
                      Stillwa                                heart
                      ter, MN
                      55082
------------------------------------------------------------------------
Monetary    Carrier  PO Box              $300    8/19/2015  Costs
             Clinic   147 252                                associated
                      Route                                  with 2015
                      601                                    Janssen
                      Belle                                  Cares
                      Mead,                                  Volunteer
                      NJ                                     Activity
                      08502
------------------------------------------------------------------------
Monetary    Catholi  25 Ikea           $4,000    10/2/2015  Catholic
             c        Drive                                  Charities,
             Charit   Westham                                Diocese of
             ies      pton,                                  Trenton On
                      NJ                                     My Own--
                      08060                                  Supportive
                                                             Housing
                                                             Program
                                                             Services
------------------------------------------------------------------------
Monetary    Catholi  25 Ikea          $15,000    10/6/2015  Partners In
             c        Drive                                  Recovery
             Charit   Westham
             ies      pton,
                      NJ
                      08060
------------------------------------------------------------------------
Monetary    Catholi  920               $4,000   11/16/2015  CYO's Broad
             c        South                                  St. Center
             Youth    Broad                                  After
             Organi   Street                                 School
             zation   Trenton                                Program
             of       , NJ                                   Tutoring
             Mercer   08611                                  Project
             County
------------------------------------------------------------------------
Monetary    Center   11                  $600    8/19/2015  Costs
             for      Minneak                                associated
             Educat   oning                                  with 2015
             ional    Road                                   Janssen
             Advanc   Fleming                                Cares
             ement    ton, NJ                                Volunteer
                      08822                                  activity
------------------------------------------------------------------------
Monetary    Center   11               $12,000   11/25/2015  CORE Values
             for      Minneak                                job
             Educat   oning                                  readiness
             ional    Road                                   program
             Advanc   Fleming
             ement    ton, NJ
                      08822
------------------------------------------------------------------------
Monetary    Child    204 N.            $3,000    9/28/2015  Teen
             Home     West                                   Prenatal
             and      Street                                 and
             Commun   #101                                   Parenting
             ity      Doylest                                Continuum
                      own, PA
                      18901
------------------------------------------------------------------------
Monetary    Childre  635               $5,000    3/30/2015  Fundraising
             n's      South                                  event
             Home     Clinton                                support to
             Societ   Avenue                                 benefit
             y of     Trenton                                general
             New      , NJ                                   mission of
             Jersey   08611                                  organizatio
                                                             n
------------------------------------------------------------------------
Monetary    Childre  635               $5,000   12/22/2015  Fundraising
             n's      South                                  event
             Home     Clinton                                support to
             Societ   Avenue                                 benefit
             y of     Trenton                                general
             New      , NJ                                   mission of
             Jersey   08611                                  organizatio
                                                             n
------------------------------------------------------------------------
Monetary    Childre  635              $10,000   12/22/2015  CUNA and
             n's      South                                  Body and
             Home     Clinton                                Soul
             Societ   Avenue                                 Prenatal
             y of     Trenton                                Health
             New      , NJ                                   Education
             Jersey   08611                                  Program
------------------------------------------------------------------------
Monetary    Cit      111 S.            $3,000   10/13/2015  Silver level
             Intern   Highlan                                sponsor of
             ationa   d St.                                  the 2016
             l,       Box 71                                 Internation
             Inc.     Memphis                                al
                      , TN                                   Conference
                      38111
------------------------------------------------------------------------
Monetary    College  50 Milk          $20,000    12/8/2015  Assessing
             Diabet   St 16th                                the unmet
             es       Floor                                  needs of
             Networ   Boston,                                young
             k,       MA                                     adults with
             Inc.     02109                                  diabetes on
                                                             college
                                                             campuses
------------------------------------------------------------------------
Monetary    College  2000             $22,500   12/17/2015  Nursing
             of New   Penning                                Merit
             Jersey   ton                                    Scholarship
                      Road                                   s ($10,000)
                      P.O.                                   and
                      Box                                    Educational
                      7718                                   Opportunity
                      Ewing,                                 Fund
                      NJ                                     Promise
                      08628                                  Awards
                                                             ($12,500)
------------------------------------------------------------------------
Monetary    Colorad  1031              $2,500    7/28/2015  Peer Support
             o        33rd                                   Coach
             Mental   Street,                                Training
             Wellne   Suite
             ss       237
             Networ   Denver,
             k        CO
                      80205
------------------------------------------------------------------------
Monetary    Communi  PO Box            $5,000    8/18/2015  Rise Summer
             ty       88 116                                 Healthy
             Action   North                                  Food
             Servic   Main                                   Initiative
             e        Street                                 for low
             Center   Hightst                                income
             , Inc.   own, NJ                                youth.
                      08520
------------------------------------------------------------------------
Monetary    Communi  PO Box          $200,000   11/25/2015  Johnson &
             ty       338                                    Johnson
             Founda   Morrist                                Somerset
             tion     own, NJ                                County
             of New   07963                                  Companies
             Jersey                                          Contributio
                                                             n Fund at
                                                             the
                                                             Community
                                                             Foundation
                                                             of NJ
------------------------------------------------------------------------
Monetary    Communi  15                $7,000   12/25/2015  Donation to
             ty       Highlan                                be split
             Health   d                                      evenly
             Charit   Avenue                                 across
             ies      Matawan                                charitable
                      , NJ                                   organizatio
                      07747                                  ns which
                                                             serve
                                                             patients in
                                                             their
                                                             therapeutic
                                                             areas
------------------------------------------------------------------------
Monetary    Communi  P.O. Box         $16,000   11/24/2015  Each One,
             ty       15176                                  Teach One:
             Health   407                                    An Evidence
             Coalit   Crutchf                                Based
             ion,     ield                                   Diabetes
             Inc.     Street                                 Self-
                      Durham,                                Management
                      NC                                     Workshop
                      27704                                  and
                                                             Community
                                                             Leaders
                                                             Training
------------------------------------------------------------------------
Monetary    Communi  959              $12,000    5/15/2015  Pathway to
             ty       Route                                  Recovery
             Hope,    46                                     Residential
             Inc.     East,                                  Programs
                      Suite                                  ($10,000)
                      402                                    The Annual
                      Parsipp                                Learning
                      any, NJ                                Forum on
                      07054                                  Mental
                                                             Health and
                                                             Wellness
                                                             Fair
                                                             ($2,000)
------------------------------------------------------------------------
Monetary    Communi  959              $12,000    10/6/2015  Hope for
             ty       Route                                  Veterans
             Hope,    46                                     and Valley
             Inc.     East,                                  Brook
                      Suite                                  Village for
                      402                                    Veterans
                      Parsipp
                      any, NJ
                      07054
------------------------------------------------------------------------
Monetary    Communi  310 W.            $5,000    9/28/2015  Making the
             ty       State                                  Invisible
             Justic   Street,                                Visible--Le
             e        3rd                                    gal
             Center   Floor                                  Services
             , Inc.   Trenton                                for the
                      , NJ                                   Underserved
                      08618
------------------------------------------------------------------------
Monetary    Communi  507 E.            $4,000     7/1/2015  Compeer
             ty       College                                Program of
             Mental   Street                                 Johnson
             Health   Iowa                                   County,
             Center   City,                                  Iowa
             For      IA
             Mid-     52245
             Easter
             n Iowa
             dba
             Compee
             r
             Progra
             m,
             Inc.
------------------------------------------------------------------------
Monetary    Compeer  259               $2,500    7/16/2015  Youth and
             Roches   Monroe                                 Family
             ter,     Avenue                                 Mentoring
             Inc.     Rochest                                Program--Fa
                      er, NY                                 mily
                      14607                                  Support
------------------------------------------------------------------------
Monetary    Contact  60 S.             $5,000    8/18/2015  Fundraising
             Of       Main                                   event
             Mercer   Street                                 support to
             County   Penning                                benefit
             New      ton, NJ                                general
             Jersey   08534                                  mission of
             , Inc.                                          organizatio
                                                             n
------------------------------------------------------------------------
Monetary    Contact  60 S.             $8,500    12/1/2015  CRISIS
             Of       Main                                   HOTLINE,
             Mercer   Street                                 CRISIS
             County   Penning                                CHAT, and
             New      ton, NJ                                TxtToday
             Jersey   08534                                  Programs
             , Inc.
------------------------------------------------------------------------
Monetary    CONTACT  P.O. Box          $3,500    5/14/2015  Crisis
             We       2376                                   Interventio
             Care,    Westfie                                n for
             Inc.     ld, NJ                                 Nonprofessi
                      07091                                  onals for
                                                             People
                                                             Experiencin
                                                             g Psychosis
------------------------------------------------------------------------
Monetary    Court    1450             $15,000   11/13/2015  CASA of
             Appoin   Parksid                                Mercer
             ted      e                                      County
             Specia   Avenue,                                Child
             l        Suite                                  Advocacy
             Advoca   22                                     Program for
             tes      Suite                                  Abused and
                      22                                     Neglected
                      Ewing,                                 Children
                      NJ
                      08638
------------------------------------------------------------------------
Monetary    Daytop   362               $2,500   12/10/2015  Daytop of NJ
             Villag   Sunset                                 at Crawford
             e Of     Rd                                     House--work
             New      Skillma                                readiness
             Jersey   n, NJ                                  initiative
             , Inc.   08558
------------------------------------------------------------------------
Monetary    Deborah  212               $2,000    11/3/2015  Women's
             Hospit   Trenton                                Heart
             al       Road                                   Health
             Founda   Browns                                 Symposium
             tion     Mills,
                      NJ
                      08015
------------------------------------------------------------------------
Monetary    Delawar  14                  $300    8/19/2015  Costs
             e        Michael                                associated
             River    McCorri                                with 2015
             Steamb   stin                                   Janssen
             oat      Road                                   Cares
             Floati   Hamilto                                Volunteer
             ng       n, NJ                                  Activity
             Classr   08690
             oom,
             Inc.
------------------------------------------------------------------------
Monetary    Delawar  14                $4,900   11/16/2015  Environmenta
             e        Michael                                l education
             River    McCorri                                for
             Steamb   stin                                   underfunded
             oat      Road                                   and
             Floati   Hamilto                                underserved
             ng       n, NJ                                  schools and
             Classr   08690                                  youth
             oom,                                            groups
             Inc.
------------------------------------------------------------------------
Monetary    Denver   3501 E               $75     2/6/2015  Employee
             Rescue   46th                                   directed
             Missio   Avenue                                 donation in
             n        Denver,                                lieu of
                      CO                                     company
                      80216                                  holiday
                                                             gift
------------------------------------------------------------------------
Monetary    Depress  C/O               $1,000     6/4/2015  DBSA NJ
             ion      David                                  Annual
             and      Mizenko                                Conference
             Bipola   5                                      for Support
             r        Village                                Group
             Suppor   Ct                                     Participant
             t        Lawrenc                                s
             Allian   eville,
             ce       NJ
                      08648
------------------------------------------------------------------------
Monetary    Depress  C/O               $1,000     6/4/2015  DBSA NJ
             ion      David                                  Mutual Aid
             and      Mizenko                                Support
             Bipola   5                                      Group
             r        Village                                Facilitator
             Suppor   Ct                                     Training
             t        Lawrenc
             Allian   eville,
             ce       NJ
                      08648
------------------------------------------------------------------------
Monetary    Desert   1695 N.           $3,500    7/28/2015  Quality of
             Aids     Sunrise                                life
             Projec   Way                                    services
             t        Palm                                   for
                      Springs                                patients
                      , CA                                   with
                      92262                                  schizophren
                                                             ia and
                                                             schizo-
                                                             affective
                                                             disorders
------------------------------------------------------------------------
Monetary    Detroit  10                $5,000    7/16/2015  InSHAPE
             Centra   Peterbo                                Program
             l City   ro                                     (Individual
             Commun   Detroit                                ized Self
             ity      , MI                                   Health
             Mental   48201                                  Action Plan
             Health                                          for
             , Inc.                                          Empowerment
                                                             )
------------------------------------------------------------------------
Monetary    Detroit  645                 $750     2/9/2015  Employee
             Metrop   Griswol                                directed
             olitan   d,                                     donation in
             Bar      Suite                                  lieu of
             Associ   1356                                   company
             ation    Detroit                                holiday
             Founda   , MI                                   gift
             tion     48226
------------------------------------------------------------------------
Monetary    Diabete  13               $15,000   10/21/2015  Medical
             s        Sunflow                                Assistance
             Founda   er                                     and Patient
             tion     Avenue,                                Support
                      Suite                                  Services
                      1010
                      Paramus
                      , NJ
                      07652
------------------------------------------------------------------------
Monetary    Diabete  13                $5,000   12/11/2015  Medical
             s        Sunflow                                Assistance
             Founda   er                                     and Patient
             tion     Avenue,                                Support
                      Suite                                  Services
                      1010
                      Paramus
                      , NJ
                      07652
------------------------------------------------------------------------
Monetary    Diabete  319 N.           $20,000    12/1/2015  DiabetesSist
             s        Weber                                  ers'
             Sister   Road,                                  Minority
             s        pmb                                    Initiative
                      #163
                      Bolingb
                      rook,
                      IL
                      60490
------------------------------------------------------------------------
Monetary    Dress    3131              $9,000   11/16/2015  Roads to
             for      Princet                                Success:
             Succes   on                                     The Latina
             s        Pike,                                  Literacy
                      Buildin                                Mobile
                      g 4,                                   Program.
                      Suite
                      209
                      Lawrenc
                      eville,
                      NJ
                      08648
------------------------------------------------------------------------
Monetary    Emory    Rollins          $10,000   12/23/2015  Emory Latino
             Univer   School                                 Diabetes
             sity     of                                     Education
                      Public                                 Program
                      Health                                 (ELDEP)
                      1518
                      Clifton
                      Rd, NE
                      Room
                      606
                      Atlanta
                      , GA
                      30322
------------------------------------------------------------------------
Monetary    Emory    Rollins          $12,500   12/23/2015  Emory Latino
             Univer   School                                 Diabetes
             sity     of                                     Education
                      Public                                 Program
                      Health                                 (ELDEP)
                      1518
                      Clifton
                      Rd, NE
                      Room
                      606
                      Atlanta
                      , GA
                      30322
------------------------------------------------------------------------
Monetary    Enable,  13                $7,500   11/12/2015  Connect with
             Inc.     Roszel                                 Enable
                      Road,
                      Suite
                      B110
                      Princet
                      on, NJ
                      08540
------------------------------------------------------------------------
Monetary    Every    Fred              $9,000   11/16/2015  Every Child
             Child    Vereen,                                Valued
             Valued   Jr.                                    After
             A NJ     Communi                                School
             Nonpro   ty                                     Program
             fit      Center
             Corpor   175
             ation    Johnson
                      Avenue
                      Lawrenc
                      eville,
                      NJ
                      08648
------------------------------------------------------------------------
Monetary    Everybo  PO Box            $4,000   11/16/2015  Coming Up
             dy       3127                                   for AIRTM
             Loves    Princet
             Kenny    on, NJ
             Projec   08543
             t,
             Inc.
------------------------------------------------------------------------
Monetary    Family   1931              $9,000     6/4/2015  Outpatient
             Guidan   Notting                                Mental
             ce       ham Way                                Health
             Center   Hamilto                                Treatment
             Corpor   n, NJ                                  for the
             ation    08619                                  Chronically
                                                             Mentally
                                                             Ill
------------------------------------------------------------------------
Monetary    Family   1931                $300    6/26/2015  Costs
             Guidan   Notting                                associated
             ce       ham Way                                with 2015
             Center   Hamilto                                Janssen
             Corpor   n, NJ                                  Cares
             ation    08619                                  Volunteer
                                                             Activity
------------------------------------------------------------------------
Monetary    Family   1931                $300    9/24/2015  Costs
             Guidan   Notting                                associated
             ce       ham Way                                with 2015
             Center   Hamilto                                Janssen
             Corpor   n, NJ                                  Cares
             ation    08619                                  Volunteer
                                                             Activity
                                                             September
------------------------------------------------------------------------
Monetary    Family   1 AAA            $10,000    10/2/2015  Get FIT @
             Resour   Dr.                                    YMCA
             ce       Suite
             Networ   203
             k        Trenton
                      , NJ
                      08691
------------------------------------------------------------------------
Monetary    Family   4                 $9,500   11/16/2015  Nursing
             Servic   Corners                                services at
             e        tone                                   the
             Associ   Drive                                  emergency
             ation    Langhor                                homelss
             of       ne, PA                                 shelter
             Bucks    19047
             County
------------------------------------------------------------------------
Monetary    Family   790 Park          $4,000    4/16/2015  STEPS to
             Servic   Avenue                                 Wellness
             e        Hunting                                program
             League   ton, NY
             , Inc.   11743
------------------------------------------------------------------------
Monetary    Federat  One               $1,000    4/16/2015  Big Nosh
             ion of   Farming                                Vocational
             Organi   dale                                   Services
             zation   Road
             s        West
                      Babylon
                      , NY
                      11704
------------------------------------------------------------------------
Monetary    Feed     Central              $75    1/14/2015  Employee
             More,    Virgini                                directed
             Inc.     a Food                                 donation in
                      Bank                                   lieu of
                      1415                                   company
                      Rhoadmi                                holiday
                      ller                                   gift
                      Street
                      Richmon
                      d, VA
                      23220
------------------------------------------------------------------------
Monetary    Feed     333 N.               $75    2/25/2015  Employee
             the      Meridia                                directed
             Childr   n                                      donation in
             en,      Avenue                                 lieu of
             Inc.     Oklahom                                company
                      a City,                                holiday
                      OK                                     gift
                      73107
------------------------------------------------------------------------
Monetary    Forsyth  61                   $75   11/19/2015  Employee
             Humane   Miller                                 directed
             Societ   Street                                 donation in
             y        Winston-                               lieu of
                      Salem,                                 Company
                      NC                                     Holiday
                      21704                                  gift
------------------------------------------------------------------------
Monetary    Foundat  2381              $2,000   11/16/2015  Fundraising
             ion of   Lawrenc                                event
             Morris   eville                                 support to
             Hall/    Road                                   benefit
             St.      Lawrenc                                general
             Lawren   eville,                                mission of
             ce       NJ                                     organizatio
                      08648                                  n
------------------------------------------------------------------------
Monetary    Foundat  2381              $7,500   11/16/2015  Communicatin
             ion of   Lawrenc                                g for
             Morris   eville                                 Success
             Hall/    Road
             St.      Lawrenc
             Lawren   eville,
             ce       NJ
                      08648
------------------------------------------------------------------------
Monetary    Fountai  425 West          $1,000    3/30/2015  Silver
             n        47th                                   sponsor
             House    Street                                 Fountain
                      New                                    House
                      York,                                  Wellness
                      NY                                     Campaign
                      10036                                  and One in
                                                             Four 5K
------------------------------------------------------------------------
Monetary    Fountai  425 West          $5,000   10/13/2015  Fundraising
             n        47th                                   event
             House    Street                                 support to
                      New                                    benefit
                      York,                                  general
                      NY                                     mission of
                      10036                                  organizatio
                                                             n
------------------------------------------------------------------------
Monetary    Gateway  11901             $7,500    7/16/2015  Support for
             Homes,   Reedy                                  an
             Inc.     Branch                                 Occupationa
                      Road                                   l Therapist
                      Chester
                      field,
                      VA
                      23238
------------------------------------------------------------------------
Monetary    Georgia  246               $1,500     7/1/2015  Consumer
             Mental   Sycamor                                scholarship
             Health   e St.                                  s to attend
             Consum   Suite                                  the 24th
             er       260                                    Annual
             Networ   Decatur                                Statewide
             k        , GA                                   Consumer
                      30030                                  Conference
------------------------------------------------------------------------
Monetary    Girl     1171              $2,000    12/3/2015  GSHNJ
             Scouts   Route                                  Robotics
             Heart    28                                     Program
             of New   North                                  Expansion--
             Jersey   Branch,                                Make It and
             , Inc.   NJ                                     Take It
                      08876
------------------------------------------------------------------------
Monetary    Greater  16 W.           $100,000   12/22/2015  Greater
             Trento   Lafayet                                Trenton
             n        te St.                                 Initiative
                      Trenton                                operating
                      , NJ                                   activities
                      08608                                  in support
                                                             of its
                                                             strategic
                                                             plan for
                                                             2015 and
                                                             2016
------------------------------------------------------------------------
Monetary    Grounds  80                $7,200   12/15/2015  Supporting
             for      Sculpto                                Wellness
             Sculpt   rs Way                                 Walks for
             ure      Hamilto                                Low Income
                      n, NJ                                  Seniors
                      08619
------------------------------------------------------------------------
Monetary    Habitat  601 N             $7,500   11/16/2015  Community
             for      Clinton                                Development
             Humani   Ave                                    Grant for 7-
             ty--Tr   Trenton                                Plex Build
             enton    , NJ
             Area     08638-
                      3446
------------------------------------------------------------------------
Monetary    Habitat  31 Oak            $4,000   11/16/2015  Women Build
             for      Ave                                    Homes and
             Humani   Chalfon                                Strong
             ty of    t, PA                                  Families
             Greate   18914
             r
             Bucks
------------------------------------------------------------------------
Monetary    Habitat  212 Yost            $300    8/24/2015  Costs
             for      Bouleva                                associated
             Humani   rd                                     with 2015
             ty of    Suite A                                Janssen
             Greate   Pittsbu                                Cares
             r        rgh, PA                                Volunteer
             Pittsb   15221                                  Activity
             urgh
------------------------------------------------------------------------
Monetary    Hamilto  1315             $15,000   12/15/2015  Healthy
             n Area   Whiteho                                Living
             YMCA     rse-                                   Programs:
                      Mercerv                                Diabetes
                      ille                                   Prevention
                      Road                                   Program
                      Hamilto                                ($7,500.00)
                      n, NJ                                  , ACT
                      08619                                  ($7,500.00)
------------------------------------------------------------------------
Monetary    Heart    1325 G           $20,000    1/19/2015  Improving
             Rhythm   Street                                 Health
             Societ   NW,                                    Literacy
             y,       Suite                                  and Health
             Inc.     400                                    Information
                      Washing                                in Atrial
                      ton, DC                                Fibrillatio
                      20005                                  n and
                                                             Stroke
                                                             Patients
------------------------------------------------------------------------
Monetary    Heartla  4750 N.           $7,500    7/16/2015  Pathways
             nd       Sherida                                Home,
             Health   n Road                                 supportive
             Outrea   Chicago                                housing
             ch       , IL                                   program for
                      60640                                  those
                                                             living with
                                                             mental
                                                             health
                                                             conditions
------------------------------------------------------------------------
Monetary    Henders  4740              $5,800     8/5/2015  Mental
             on       North                                  Health
             Behavi   State                                  First Aid:
             oral     Road 7                                 Helping
             Health   Lauderd                                Persons in
                      ale                                    Need
                      Lakes,
                      FL
                      33319
------------------------------------------------------------------------
Monetary    HiTops,  21                $6,000   11/12/2015  HiTops'
             Inc.     Wiggins                                Adolescent
                      Street                                 Women and
                      Princet                                Girls'
                      on, NJ                                 Sexual
                      08540                                  Health
                                                             Programming
------------------------------------------------------------------------
Monetary    Homecar  240                 $100     8/5/2015  Memorial
             e and    North                                  donation
             Hospic   Radnor-
             e        -Cheste
             Founda   r Road,
             tion     Suite
                      100
                      Radnor,
                      PA
                      19087-
                      5174
------------------------------------------------------------------------
Monetary    HomeFro  1880                $365    7/10/2015  Costs
             nt       Princet                                associated
                      on Ave.                                with 2015
                      Lawrenc                                Janssen
                      eville,                                Cares
                      NJ                                     Volunteer
                      08648                                  Activity
------------------------------------------------------------------------
Monetary    HomeFro  1880              $9,000   10/13/2015  Huchet House
             nt       Princet
                      on Ave.
                      Lawrenc
                      eville,
                      NJ
                      08648
------------------------------------------------------------------------
Monetary    Hopewel  35                  $750   11/16/2015  Hopewell
             l        Princet                                Elementary
             Elemen   on                                     Science
             tary     Avenue                                 Fair 2016
             School   Hopewel
             Parent   l, NJ
             Teache   08525
             r
             Organi
             zation
             , Inc.
------------------------------------------------------------------------
Monetary    Hopewel  P.O. Box            $750   12/21/2015  ``aMAZing
             l        145                                    Pumpkin
             Valley   Hopewel                                Carve''
             Arts     l, NJ                                  Exhibition
             Counci   08525
             l,
             Inc.
------------------------------------------------------------------------
Monetary    Hopewel  PO Box            $5,400    7/27/2015  Scholarship
             l        553                                    for a
             Valley   Penning                                Hopewell
             Educat   ton, NJ                                Valley
             ion      08534                                  Regional
             Founda                                          School
             tion                                            District
                                                             graduating
                                                             student
                                                             ($1,000),
                                                             district-
                                                             wide
                                                             workshops
                                                             on
                                                             childhood
                                                             mental
                                                             health
                                                             ($4,400)
------------------------------------------------------------------------
Monetary    Hopewel  48                $2,500    2/12/2015  Hopewell
             l        Orchard                                Valley
             Valley   Avenue                                 Rides
             Senior   Penning
             Founda   ton, NJ
             tion     08534
------------------------------------------------------------------------
Monetary    Humane   1201                 $75     2/3/2015  Employee
             Societ   Macklin                                directed
             y of     d                                      donation in
             Missou   Avenue                                 lieu of
             ri       St.                                    company
                      Louis,                                 holiday
                      MO                                     gift
                      63110
------------------------------------------------------------------------
Monetary    Hunterd  1410                $300    8/19/2015  Costs
             on       Route                                  associated
             County   22 West                                with 2015
             YMCA     Annanda                                Janssen
                      le, NJ                                 Cares
                      08801                                  Volunteer
                                                             Activity
------------------------------------------------------------------------
Monetary    Hunterd  1410              $2,500   10/13/2015  Fundraising
             on       Route                                  event
             County   22 West                                support to
             YMCA     Annanda                                benefit
                      le, NJ                                 general
                      08801                                  mission of
                                                             organizatio
                                                             n
------------------------------------------------------------------------
Monetary    Hunterd  8 Main           $10,000    4/20/2015  Prescription
             on       Street                                 Drug Abuse
             Drug     Fleming                                Education
             Awaren   ton, NJ                                and
             ess      08822                                  Evaluation
             Progra                                          Project.
             m,
             Inc.
------------------------------------------------------------------------
Monetary    Hunterd  111 Mine          $1,000    12/8/2015  Stewardship
             on       Street                                 of the
             Land     Fleming                                Hunterdon
             Trust    ton, NJ                                Land
                      08822                                  Trust's
                                                             Dvoor Farm
                                                             Preserve
------------------------------------------------------------------------
Monetary    Institu  P.O. Box          $3,500    10/2/2015  Nursing
             te of    7869                                   Experiences
             Wonder   West                                   hip Program
             ful      Trenton
             Women    , NJ
             Workin   08628
             g For
             Empowe
             rment
------------------------------------------------------------------------
Monetary    Interfa  3635             $15,000   11/13/2015  Neighbors
             ith      Quakerb                                Helping
             Caregi   ridge                                  Neighbors
             vers     Rd.                                    Program
             Trento   Suite
             n,       16
             Inc.     Hamilto
                      n, NJ
                      08619
------------------------------------------------------------------------
Monetary    Isles,   10 Wood           $7,500   11/16/2015  Healthy
             Inc.     Street                                 Homes
                      Trenton                                Training to
                      , NJ                                   Reduce
                      08618                                  Asthma and
                                                             Lead
------------------------------------------------------------------------
Monetary    Jewish   707                 $300    7/14/2015  Costs
             Family   Alexand                                associated
             and      er                                     with 2015
             Childr   Road,                                  Janssen
             en's     Suite                                  Cares
             Servic   102                                    Volunteer
             e of     Princet                                Activity
             Greate   on, NJ
             r        08540
             Mercer
             County
------------------------------------------------------------------------
Monetary    Jewish   707               $7,500   12/15/2015  Mercer
             Family   Alexand                                County
             and      er                                     Caregiver
             Childr   Road,                                  Help Line
             en's     Suite                                  and
             Servic   102                                    Caregiver
             e of     Princet                                Services
             Greate   on, NJ                                 2016
             r        08540
             Mercer
             County
------------------------------------------------------------------------
Monetary    Jewish   707              $10,000   12/15/2015  Fundraising
             Family   Alexand                                event
             and      er                                     support to
             Childr   Road,                                  benefit
             en's     Suite                                  general
             Servic   102                                    mission of
             e of     Princet                                organizatio
             Greate   on, NJ                                 n
             r        08540
             Mercer
             County
------------------------------------------------------------------------
Monetary    Johnson  One           $6,000,000    6/29/2015  Funding to
             &        Johnson                                support the
             Johnso   &                                      Johnson &
             n        Johnson                                Johnson
             Patien   Plaza                                  Patient
             t        New                                    Assistance
             Assist   Brunswi                                Foundation
             ance     ck, NJ                                 (JJPAF) to
             Founda   08933                                  help fund
             tion                                            their
                                                             mission to
                                                             provide
                                                             pharmaceuti
                                                             cal product
                                                             to needy
                                                             patients on
                                                             a
                                                             nondiscrimi
                                                             natory
                                                             basis
                                                             without
                                                             charge
------------------------------------------------------------------------
Monetary    Junior   4365              $5,850    9/25/2015  2016 J&J
             Achiev   Route 1                                Pharma Day
             ement    South,                                 Program
             of New   2nd
             Jersey   flr.
                      Princet
                      on, NJ
                      08540
------------------------------------------------------------------------
Monetary    Kansas   1919                $450    1/10/2015  Employee
             Foodba   East                                   directed
             nk       Douglas                                donation in
             Wareho   Wichita                                lieu of
             use      , KS                                   company
                      67211                                  holiday
                                                             gift
------------------------------------------------------------------------
Monetary    Kidsbri  4556              $7,500    9/28/2015  Kidsbridge
             dge,     South                                  Anti-
             Inc.     Broad                                  Bullying
                      St, 2nd                                Life Skills
                      Floor                                  Program for
                      Trenton                                At-Risk
                      , NJ                                   Children in
                      08620                                  Trenton at
                                                             the
                                                             Elementary
                                                             School
                                                             Level
------------------------------------------------------------------------
Monetary    Lawrenc  PO Box            $2,500   11/16/2015  WaterBotics:
             e        6531 17                                An
             Townsh   Philips                                underwater
             ip       Ave.                                   robotics
             Educat   Lawrenc                                program for
             ion      eville,                                6th grade
             Founda   NJ                                     students in
             tion,    08648                                  Lawrence
             Inc.                                            Township
                                                             Public
                                                             Schools
------------------------------------------------------------------------
Monetary    Leyden   10001 W           $5,000    6/23/2015  Peer Support
             Family   Grand                                  Center
             Servic   Ave
             e and    Frankli
             Mental   n Park,
             Health   IL
             Center   60131
------------------------------------------------------------------------
Monetary    Literac  55                $2,500   11/12/2015  Early
             y And    Primros                                Childhood--
             Life,    e                                      Building
             Inc.     Circle                                 Blocks for
                      Princet                                the Future
                      on, NJ                                 Program
                      08540
------------------------------------------------------------------------
Monetary    Literac  121               $5,000    9/28/2015  Adult
             y New    Chestnu                                Literacy
             Jersey   t                                      Program
             , Inc.   Street
                      Suite
                      203
                      Roselle
                      , NJ
                      07203
------------------------------------------------------------------------
Monetary    Literac  120               $4,000    12/1/2015  Let's Talk
             y        Findern                                About
             Volunt   e Ave--                                Health
             eers     Box 7                                  Literacy
             of       Bridgew
             Somers   ater,
             et       NJ
             County   08807
------------------------------------------------------------------------
Monetary    Main     8                 $2,500    4/16/2015  Serious
             Street   Marcell                                Mental
             Counse   a                                      Disorders:
             ling     Avenue                                 Improving
             Center   West                                   Access to
                      Orange,                                Treatment
                      NJ                                     Without
                      07052                                  Insurance
                                                             As an
                                                             Obstacle
------------------------------------------------------------------------
Monetary    Massach  15                $4,000    2/25/2015  Changing
             usetts   Vernon                                 Minds and
             Clubho   Street                                 Improving
             use      Waltham                                Lives of
             Coalit   , MA                                   People with
             ion      02453                                  Mental
                                                             Illness
                                                             Project
------------------------------------------------------------------------
Monetary    McCarte  91               $12,000   12/15/2015  OnStage
             r        Univers                                Seniors: A
             Theatr   ity                                    Community
             e        Place                                  Project of
             Compan   Princet                                McCarter
             y        on, NJ                                 Theatre
                      08450
------------------------------------------------------------------------
Monetary    Meals    5 Walter            $300    8/20/2015  Costs
             On       Foran                                  associated
             Wheels   Blvd                                   with 2015
             In       Suite                                  Janssen
             Hunter   2006                                   Cares
             don,     Fleming                                Volunteer
             Inc.     ton, NJ                                Activity
                      08822
------------------------------------------------------------------------
Monetary    Meals    320              $15,000    10/2/2015  Meals on
             on       Hollowb                                Wheels
             Wheels   rook                                   Program
             of       Drive
             Trento   Ewing,
             n        NJ
             Ewing    08638
------------------------------------------------------------------------
Monetary    Mental   2000 N.          $90,000   12/17/2015  It's My
             Health   Beaureg                                Life:
             Americ   ard St.                                Social Self
             a        6th                                    Directed
                      Floor                                  Care
                      Alexand
                      ria, VA
                      22311
------------------------------------------------------------------------
Monetary    Mental   2221             $15,000    7/27/2015  School
             Health   Norfolk                                Behavioral
             Americ   , Suite                                Health
             a of     810                                    Initiative
             Greate   Houston
             r        , TX
             Housto   77098
             n
------------------------------------------------------------------------
Monetary    Mental   2323 W           $10,000     8/6/2015  Get
             Health   5th                                    Connected
             Americ   Ave.                                   program
             a of     Suite
             Frankl   160
             in       Columbu
             County   s, OH
                      43204
------------------------------------------------------------------------
Monetary    Mental   205               $1,500     9/4/2015  2015 Montana
             Health   Haggert                                Mental
             Americ   y Lane,                                Health
             a of     Suite                                  Policy
             Montan   170                                    Summit
             a        Bozeman
                      , MT
                      59715
------------------------------------------------------------------------
Monetary    Mental   1210 San          $2,500    8/10/2015  Mental
             Health   Antonio                                Health
             Americ   , Suite                                Education
             a of     200                                    and
             Texas    Austin,                                Advocacy
                      TX                                     Campaign
                      78701
------------------------------------------------------------------------
Monetary    Mental   100 W.            $1,000    4/16/2015  Bronze
             Health   10th                                   sponsor
             Associ   St.                                    2015 E-
             ation    Ste.                                   Racing the
             in       600                                    Blues for
             Delawa   Wilming                                Mental
             re       ton, DE                                Health
                      19801
------------------------------------------------------------------------
Monetary    Mental   100 W.            $1,500    9/25/2015  Annual
             Health   10th                                   Community
             Associ   St.                                    Mental
             ation    Ste.                                   Health
             in       600                                    Conference-
             Delawa   Wilming                                -Understand
             re       ton, DE                                ing Mental
                      19801                                  Wellness
------------------------------------------------------------------------
Monetary    Mental   617               $2,500    5/22/2015  Support of
             Health   Garden                                 the Mental
             Associ   Street                                 Wellness
             ation    Santa                                  Center
             in       Barbara
             Santa    , CA
             Barbar   93101
             a
             County
------------------------------------------------------------------------
Monetary    Mental   3701              $7,500     6/4/2015  ParentVOICE:
             Health   Latrobe                                Bringing
             Associ   Drive,                                 Hope to
             ation    Suite                                  Families in
             of       140                                    Need
             Centra   Charlot
             l        te, NC
             Caroli   28211
             nas,
             Inc.
------------------------------------------------------------------------
Monetary    Mental   1301             $10,000    7/27/2015  Equitable
             Health   York                                   Access to
             Associ   Road,                                  Effective
             ation    Suite                                  Care
             of       505                                    Project--(p
             Maryla   Lutherv                                rint, web,
             nd,      ille,                                  media,
             Inc.     MD                                     salaries)
                      21093
------------------------------------------------------------------------
Monetary    Mental   580               $1,000    2/25/2015  Supporting
             Health   White                                  sponsor
             Associ   Plains                                 2015 MHA on
             ation    Road                                   the Move:
             of       Suite                                  Run/Walk
             Westch   510
             ester    Tarryto
                      wn, NY
                      10591
------------------------------------------------------------------------
Monetary    Mental   1870              $2,000    4/16/2015  Costs
             Health   South                                  associated
             Associ   Boulder                                with Peer
             ation    Avenue                                 Outreach
             Oklaho   Tulsa,                                 Services
             ma       OK                                     program
                      74119
------------------------------------------------------------------------
Monetary    Mental   555 N             $4,000    6/22/2015  MHA Housing
             Health   Woodlaw                                Initiative:
             Associ   n, Ste.                                Ensuring
             ation    3105                                   Housing for
             Reside   Wichita                                Our Most
             ntial    , KS                                   Vulnerable
             Care,    67208                                  Populations
             Inc.
------------------------------------------------------------------------
Monetary    Mental   3809             $10,000    7/28/2015  Outreach and
             Illnes   Rosewoo                                Behavioral
             s        d Drive                                Healthcare
             Recove   PO Box                                 for
             ry       4246                                   Homeless
             Center   Columbi                                Individuals
             , Inc.   a, SC                                  with Mental
                      29240                                  Illness
------------------------------------------------------------------------
Monetary    Mercer   3150              $8,000   11/16/2015  Integrating
             Allian   Brunswi                                housing and
             ce to    ck Pike                                healthcare
             End      Lawrenc                                access for
             Homele   eville,                                veteran and
             ssness   NJ                                     senior
                      08648-                                 homeless
                      2420                                   populations
                                                             in the
                                                             Trenton/
                                                             Mercer
                                                             CEASE
                                                             HOMELESSNES
                                                             S System
------------------------------------------------------------------------
Monetary    Mercer   PO Box           $19,500   12/15/2015  Supporting
             County   17202                                  STEM
             Commun   Trenton                                Education:
             ity      , NJ                                   Making
             Colleg   08690                                  Physics
             e                                               Available
             Founda                                          to Students
             tion                                            at the
                                                             James
                                                             Kerney
                                                             Campus at
                                                             Trenton
------------------------------------------------------------------------
Monetary    Mercer   151                 $300    7/10/2015  Costs
             Street   Mercer                                 associated
             Friend   Street                                 with 2015
             s        Trenton                                Janssen
                      , NJ                                   Cares
                      08611                                  Volunteer
                                                             Activity
------------------------------------------------------------------------
Monetary    Mercer   151              $20,000   10/23/2015  Food Bank-
             Street   Mercer                                 Food
             Friend   Street                                 Distributio
             s        Trenton                                n Programs
                      , NJ
                      08611
------------------------------------------------------------------------
Monetary    Middle   P.O. Box         $15,000   11/24/2015  Outreach
             Earth    8045                                   Program and
                      520                                    Community
                      North                                  Youth
                      Bridge                                 Centers
                      Street
                      Bridgew
                      ater,
                      NJ
                      08807
------------------------------------------------------------------------
Monetary    MIDJers  1A                $1,500   11/23/2015  Urban Youth
             ey       Quakerb                                Employment
             Center   ridge                                  Initiative
             for      Plaza
             Econom   Drive,
             ic       Suite 2
             Develo   Hamilto
             pment    n, NJ
                      08619
------------------------------------------------------------------------
Monetary    Midland  60                $7,500    10/6/2015  Midland
             Adult    Industr                                Meals on
             Servic   ial                                    Wheels
             es,      Parkway                                Employment
             Inc.     PO Box                                 Training
                      5026                                   Program
                      North
                      Branch,
                      NJ
                      08876
------------------------------------------------------------------------
Monetary    Mighty   10th and            $100    5/14/2015  Memorial
             Rivers   Poplar                                 Donation
             Region   Cairo,
             al       IL
             Worshi   62914
             p
             Center
------------------------------------------------------------------------
Monetary    Millhil  101              $15,000    10/2/2015  Millhill
             l        Oakland                                Trenton
             Child    Street                                 PEERS
             and      Trenton
             Family   , NJ
                      08618
------------------------------------------------------------------------
Monetary    Millhil  101               $5,000    10/2/2015  Trenton Area
             l        Oakland                                Stakeholder
             Child    Street                                 s
             and      Trenton
             Family   , NJ
                      08618
------------------------------------------------------------------------
Monetary    Minding  2083              $5,000     6/4/2015  Minding Our
             Our      Lawrenc                                Business
             Busine   eville                                 Summer
             ss,      Road                                   Program: A
             Inc.     Lawrenc                                Bridge to
                      eville,                                the Future
                      NJ                                     for Mercer
                      08648                                  County Low-
                                                             Income
                                                             Youth
------------------------------------------------------------------------
Monetary    Morven   55                $5,000    9/28/2015  Morven
             Museum   Stockto                                Museum and
             and      n                                      Garden
             Garden   Street                                 Summer
                      Princet                                Internship
                      on, NJ                                 Program for
                      08540                                  Isles of
                                                             Trenton
                                                             Youths
------------------------------------------------------------------------
Monetary    Mount    73 North         $15,000    11/2/2015  Mount Carmel
             Carmel   Clinton                                Guild Home
             Guild    Avenue                                 Health
                      Trenton                                Nursing
                      , NJ                                   Program
                      08609
------------------------------------------------------------------------
Monetary    NAMI--C  1904              $2,000    4/10/2015  Community
             VA       Byrd                                   Mental
             Centra   Avenue,                                Health
             l        Suite                                  Education
             Virgin   207                                    and Social
             ia's     (POB                                   Inclusion
             Voice    18086)
             on       Richmon
             Mental   d, VA
             Illnes   23230
             s
------------------------------------------------------------------------
Monetary    Nami     1401 I-           $1,000     7/1/2015  Bronze
             Alabam   85                                     sponsor
             a        Parkway                                2015 NAMI
                      , Suite                                Alabama
                      A                                      Walk
                      Montgom
                      ery, AL
                      36106
------------------------------------------------------------------------
Monetary    NAMI     2400 W.           $1,000    2/12/2015  Bronze
             Delawa   4th St.                                sponsor
             re       Wilming                                2015
                      ton, DE                                NAMIWalks
                      19805                                  Delaware
------------------------------------------------------------------------
Monetary    NAMI     3371              $9,500    8/18/2015  Education
             Mercer   Brunswi                                and Support
             NJ       ck                                     Programs
                      Pike,
                      Suite
                      124
                      Lawrenc
                      eville,
                      NJ
                      08648
------------------------------------------------------------------------
Monetary    NAMI     85 N.             $1,000     8/6/2015  Bronze
             New      State                                  sponsor
             Hampsh   Street                                 2015
             ire      Concord                                NAMIWalks
                      , NH                                   New
                      03301                                  Hampshire
------------------------------------------------------------------------
Monetary    NAMI of  2100              $7,500    7/28/2015  Living Room-
             DuPage   Manches                                Peer to
             County   ter Rd,                                Peer
             Illino   Bldg B,                                program
             is       Suite
                      925
                      Wheaton
                      , IL
                      60187
------------------------------------------------------------------------
Monetary    NAMI of  One               $1,500     7/1/2015  Start to
             Lake     Victori                                Finish
             County   a Sq.,                                 sponsor
                      Ste.                                   2015
                      260                                    Strides for
                      Painesv                                Awareness
                      ille,                                  Walk
                      OH
                      44077
------------------------------------------------------------------------
Monetary    NAMI of  One               $2,000     7/1/2015  Supporting
             Lake     Victori                                Families
             County   a Sq.,                                 and
                      Ste.                                   Individuals
                      260                                    Impacted by
                      Painesv                                Schizophren
                      ille,                                  ia: NAMI
                      OH                                     Family-to-
                      44077                                  Family
                                                             Education
------------------------------------------------------------------------
Monetary    NAMI of  100 W.            $1,000    2/13/2015  Bronze
             PA       Main                                   sponsor
             Montgo   Street                                 2015
             mery     Suite                                  Greater
             County   204                                    Philadelphi
                      Lansdal                                a NAMIWalk
                      e, PA
                      19446
------------------------------------------------------------------------
Monetary    NAMI of  6122 E            $1,000   12/15/2015  Bronze
             Southe   22nd St                                sponsor
             rn       Tucson,                                2016
             Arizon   AZ                                     Southern
             a        85711                                  Arizona
                                                             NAMIWalks
------------------------------------------------------------------------
Monetary    NAMI     1750 S.           $1,000    2/27/2015  Bronze
             St.      Brentwo                                sponsor
             Louis    od                                     2015 St.
                      Blvd.                                  Louis
                      Suite                                  NAMIWalks
                      511 St.
                      Louis,
                      MO
                      63144
------------------------------------------------------------------------
Monetary    NAMI     150               $1,000    5/14/2015  Bronze
             Summit   Cross                                  sponsor
             County   Street,                                2015
                      Akron                                  NAMIWalks
                      Ohio
                      44311
                      PO Box
                      462,
                      Cuyahog
                      a
                      Falls,
                      Ohio
                      44222
                      Akron,
                      OH
                      44311
------------------------------------------------------------------------
Monetary    NAMI     5251              $1,000    3/13/2015  Bronze
             Ventur   Verdugo                                sponsor
             a        Way, #K                                2015
             County   (PO Box                                NAMIWalk
                      1613)                                  Ventura
                      Camaril                                County
                      lo, CA
                      93011
------------------------------------------------------------------------
Monetary    NAMI     217               $1,000    6/10/2015  Bronze
             Waukes   Wiscons                                sponsor
             ha       in Ave                                 2015
                      Suite                                  NAMIWalks
                      300                                    in Waukesha
                      Waukesh
                      a, WI
                      53186
------------------------------------------------------------------------
Monetary    Nationa  90 Park           $2,500    8/10/2015  27th Annual
             l        Avenue                                 New York
             Allian   16                                     Mental
             ce for   Floor                                  Health
             Resear   New                                    Research
             ch on    York,                                  Symposium
             Schizo   NY
             phreni   10016
             a and
             Depres
             sion
------------------------------------------------------------------------
Monetary    Nationa  90 Park           $2,500    9/13/2015  Meet the
             l        Avenue                                 Scientist:
             Allian   16                                     A Virtual
             ce for   Floor                                  Q&A Webinar
             Resear   New                                    Series
             ch on    York,
             Schizo   NY
             phreni   10016
             a and
             Depres
             sion
------------------------------------------------------------------------
Monetary    Nationa  100               $1,000    1/20/2015  Bronze
             l        Clearbr                                sponsor
             Allian   ook                                    2015 NAMI
             ce for   Drive                                  Walks
             the      Elmsfor                                Westchester
             Mental   d, NY
             ly Ill   10523
------------------------------------------------------------------------
Monetary    Nationa  576               $1,000    1/20/2015  Bronze
             l        Farming                                sponsor
             Allian   ton                                    2015 NAMI
             ce for   Avenue                                 Connecticut
             the      Hartfor                                Walk
             Mental   d, CT
             ly Ill   06105
------------------------------------------------------------------------
Monetary    Nationa  3250              $1,000    2/13/2015  Bronze
             l        Wilshir                                sponsor
             Allian   e                                      2015
             ce for   Blvd.,                                 NAMIWalk
             the      Suite                                  Los Angeles
             Mental   1501                                   County
             ly Ill   Los
                      Angeles
                      , CA
                      90010
------------------------------------------------------------------------
Monetary    Nationa  309 W.            $1,000    2/25/2015  Bronze
             l        Millbro                                sponsor
             Allian   ok                                     2015
             ce for   Road,                                  NAMIWalks
             the      Suite
             Mental   121
             ly Ill   Raleigh
                      , NC
                      27609
------------------------------------------------------------------------
Monetary    Nationa  1706              $1,000    3/12/2015  Bronze
             l        Brady                                  sponsor
             Allian   Street                                 2015
             ce for   Suite                                  NAMIWalk
             the      101                                    Greater
             Mental   Davenpo                                Mississippi
             ly Ill   rt, IA                                 Valley
                      52803
------------------------------------------------------------------------
Monetary    Nationa  5095              $1,000    3/12/2015  Bronze
             l        Murphy                                 sponsor
             Allian   Canyon                                 2015 San
             ce for   Road,                                  Diego
             the      Suite                                  County NAMI
             Mental   320 San                                Walk
             ly Ill   Diego,
                      CA
                      92123
------------------------------------------------------------------------
Monetary    Nationa  The               $1,000    3/30/2015  Bronze
             l        Schraff                                sponsor
             Allian   t's                                    2015
             ce for   Center,                                NAMIWalks
             the      529                                    Massachuset
             Mental   Main                                   ts
             ly Ill   Street
                      Suite
                      1M17
                      Boston,
                      MA
                      02129
------------------------------------------------------------------------
Monetary    Nationa  800               $5,000    4/17/2015  Understandin
             l        Transfe                                g
             Allian   r Road                                 Psychosis:
             ce for   #31 St.                                Resources
             the      Paul,                                  and
             Mental   MN                                     Recovery
             ly Ill   55114
------------------------------------------------------------------------
Monetary    Nationa  3250              $5,000    5/14/2015  Crisis
             l        Wilshir                                Interventio
             Allian   e                                      n Team
             ce for   Blvd.,                                 training
             the      Suite                                  for Custody
             Mental   1501                                   Program for
             ly Ill   Los                                    Los Angeles
                      Angeles                                County
                      , CA                                   Sheriff's
                      90010                                  Department
------------------------------------------------------------------------
Monetary    Nationa  1225             $10,000    5/14/2015  2015 State
             l        Dublin                                 Conference
             Allian   Road,
             ce for   Suite
             the      125
             Mental   Columbu
             ly Ill   s, OH
                      43215
------------------------------------------------------------------------
Monetary    Nationa  1 Bangor          $1,000    6/10/2015  Supporter
             l        Street                                 sponsor
             Allian   Augusta                                2015 NAMI
             ce for   , ME                                   Maine
             the      04330                                  Annual
             Mental                                          Awareness
             ly Ill                                          Walk Walk
                                                             the Walk to
                                                             Start the
                                                             Talk
------------------------------------------------------------------------
Monetary    Nationa  3440              $1,000    6/10/2015  Bronze
             l        Viking                                 sponsor
             Allian   Drive                                  2016
             ce for   Suite                                  Northern
             the      104                                    California
             Mental   Sacrame                                NAMI Walk
             ly Ill   nto, CA
                      95827
------------------------------------------------------------------------
Monetary    Nationa  PO Box            $1,000    7/15/2015  Platinum
             l        550039                                 level
             Allian   Birming                                sponsor
             ce for   ham, AL                                NAMI
             the      35255-                                 Birmingham
             Mental   0039                                   2015 Walk
             ly Ill                                          for Mental
                                                             Health
------------------------------------------------------------------------
Monetary    Nationa  808               $1,000    7/15/2015  2015 Annual
             l        Montice                                Conference,
             Allian   llo                                    ``Shatterin
             ce for   Street                                 g the
             the      Somerse                                Stigma--Fac
             Mental   t, KY                                  ts vs.
             ly Ill   42501                                  Fiction--Ho
                                                             w Much Do
                                                             You Know?''
------------------------------------------------------------------------
Monetary    Nationa  1536 W            $6,000    7/16/2015  Coming out
             l        Chicago                                Proud
             Allian   Chicago                                Program
             ce for   , IL
             the      60642
             Mental
             ly Ill
------------------------------------------------------------------------
Monetary    Nationa  PO Box            $1,000    7/20/2015  2015 Mental
             l        4096                                   Health
             Allian   2206 N.                                Awareness
             ce for   Gordon                                 Conference
             the      Street                                 (MHAC)
             Mental   Alvin,
             ly Ill   TX
                      77512
------------------------------------------------------------------------
Monetary    Nationa  2059              $1,000    7/28/2015  Bronze
             l        Atwood                                 sponsor
             Allian   Avenue                                 2015 Dane
             ce for   Madison                                County
             the      , WI                                   NAMIWalk
             Mental   53704
             ly Ill
------------------------------------------------------------------------
Monetary    Nationa  P.O Box           $1,500    8/25/2015  Silver
             l        8260                                   sponsor
             Allian   Richmon                                2015
             ce for   d, VA                                  NAMIWalks
             the      23226                                  Virginia
             Mental
             ly Ill
------------------------------------------------------------------------
Monetary    Nationa  99 Pine           $4,000    8/28/2015  2015 NAMI-
             l        St.                                    NYS
             Allian   Suite                                  Education
             ce for   302                                    Conference-
             the      Albany,                                Redefining
             Mental   NY                                     Recovery:
             ly Ill   12207                                  New
                                                             Challenges,
                                                             New
                                                             Opportuniti
                                                             es, New
                                                             Hopes
------------------------------------------------------------------------
Monetary    Nationa  2601              $2,000    8/28/2015  Support of
             l        Cold                                   the 2015
             Allian   Spring                                 NAMI
             ce for   Road                                   Indiana
             the      P.O.                                   State
             Mental   Box                                    Conference
             ly Ill   22697
                      Indiana
                      polis,
                      IN
                      46222
------------------------------------------------------------------------
Monetary    Nationa  1562              $2,500    9/25/2015  Healing
             l        Route                                  Ourselves,
             Allian   130                                    Healing
             ce for   North                                  Others:
             the      Brunswi                                NAMI NJ
             Mental   ck, NJ                                 2015 Annual
             ly Ill   08902                                  Conference
------------------------------------------------------------------------
Monetary    Nationa  3803 N.          $75,000   12/17/2015  NAMI
             l        Fairfax                                Helpline
             Allian   Drive
             ce for   Suite
             the      100
             Mental   Arlingt
             ly Ill   on, VA
                      22203
------------------------------------------------------------------------
Monetary    Nationa  3803 N.          $50,000   12/17/2015  NAMI
             l        Fairfax                                Multicultur
             Allian   Drive                                  al Action
             ce for   Suite                                  Center
             the      100
             Mental   Arlingt
             ly Ill   on, VA
                      22203
------------------------------------------------------------------------
Monetary    Nationa  2012              $1,000    6/10/2015  Bronze
             l        West                                   sponsor
             Allian   25th                                   NAMIWalks
             ce for   Street,                                2015
             the      #600
             Mental   Clevela
             ly       nd, OH
             Ill--G   44113
             reater
             Clevel
             and
------------------------------------------------------------------------
Monetary    Nationa  2012              $2,000    6/23/2015  Mental
             l        West                                   Illness
             Allian   25th                                   Peer
             ce for   Street,                                Support and
             the      #600                                   Education
             Mental   Clevela                                programs
             ly       nd, OH
             Ill--G   44113
             reater
             Clevel
             and
------------------------------------------------------------------------
Monetary    Nationa  2753              $1,000    2/13/2015  Bronze
             l        West                                   sponsor
             Allian   Central                                2015 NAMI
             ce for   Avenue                                 Walk
             the      Toledo,
             Mental   OH
             ly Ill   43606
             of
             Greate
             r
             Toledo
------------------------------------------------------------------------
Monetary    Nationa  505 8th           $1,000    2/25/2015  Bronze
             l        Avenue,                                sponsor
             Allian   Ste                                    2015
             ce for   1103                                   NAMIWalks
             the      New                                    NYC
             Mental   York,
             ly Ill   NY
             of New   10018
             York
             City
------------------------------------------------------------------------
Monetary    Nationa  1981              $1,000   11/17/2015  Bronze
             l        Marcus                                 sponsor
             Allian   Ave,                                   2016 Long
             ce for   C117                                   Island/
             the      Lake                                   Queens/
             Mental   Success                                NAMIWalks
             ly Ill   , NY
             Queens/  11042
             Nassau
------------------------------------------------------------------------
Monetary    Nationa  5963              $1,000    7/27/2015  Bronze
             l        Boymel                                 sponsor
             Allian   Dr.                                    2015
             ce on    Fairfie                                National
             Mental   ld, OH                                 Alliance on
             Illnes   45014                                  Mental
             s                                               Illness of
                                                             Butler
                                                             County
                                                             NAMIWAlk
------------------------------------------------------------------------
Monetary    Nationa  324A              $1,000     1/9/2015  Gold sponsor
             l        Springf                                of the 2015
             Allian   ield                                   NAMI-WM
             ce on    Street                                 Annual
             Mental   Agawam,                                Walkathon:
             Illnes   MA                                     A Journey
             s        01001                                  of Hope and
             Wester                                          Recovery
             n
             Mass.,
             Inc.
------------------------------------------------------------------------
Monetary    Nationa  PO Box            $6,000    4/16/2015  28 Annual
             l Art    350891                                 National
             Exhibi   Miami,                                 Art
             tions    FL                                     Exhibition
             of the   33135                                  by the
             Mental                                          Mentally
             ly                                              Ill
             Ill,
             Inc.
------------------------------------------------------------------------
Monetary    Nationa  110 N            $30,000    12/1/2015  MY BLOOD
             l        Washing                                CLOT--An
             Blood    ton St.                                Online
             Clot     Suite                                  Resource
             Allian   328                                    for
             ce       Rockvil                                Patients
                      le, MD                                 and
                      20850                                  Caregivers
                                                             Managing
                                                             Life with
                                                             VTE
------------------------------------------------------------------------
Monetary    Nationa  1400 K           $75,000   12/17/2015  2016 Policy
             l        Street                                 Action
             Counci   NW,                                    Center
             l for    Suite
             Behavi   400
             oral     Washing
             Health   ton, DC
                      20005
------------------------------------------------------------------------
Monetary    Nationa  1400 K           $75,000   12/17/2015  Early Onset
             l        Street                                 Psychosis
             Counci   NW,                                    Project
             l for    Suite
             Behavi   400
             oral     Washing
             Health   ton, DC
                      20005
------------------------------------------------------------------------
Monetary    Nationa  1400 K           $75,000   12/17/2015  Health
             l        Street                                 Justice
             Counci   NW,                                    Learning
             l for    Suite                                  Initiative
             Behavi   400
             oral     Washing
             Health   ton, DC
                      20005
------------------------------------------------------------------------
Monetary    Nationa  949 W.            $7,500   11/16/2015  Academic
             l        State                                  Creative
             Junior   Street                                 Engagement
             Tennis   Trenton                                (ACE) and
             and      , NJ                                   STEM Pilot
             Learni   08618                                  Program
             ng of
             Trento
             n
------------------------------------------------------------------------
Monetary    Nationa  9707 E              $100    11/3/2015  Memorial
             l        Easter                                 Donation
             Stroke   Lane,
             Associ   Suite B
             ation    Centenn
                      ial, CO
                      80112
------------------------------------------------------------------------
Monetary    Nationa  9707 E           $15,000    12/3/2015  Navigator
             l        Easter                                 training,
             Stroke   Lane,                                  program
             Associ   Suite B                                development
             ation    Centenn                                , services
                      ial, CO                                delivered,
                      80112                                  participant
                                                             materials
                                                             and
                                                             resources,
                                                             and
                                                             outcomes
                                                             measurement
                                                             .
------------------------------------------------------------------------
Monetary    Nationa  9707 E           $35,000    12/4/2015  Develop a
             l        Easter                                 multi-
             Stroke   Lane,                                  channel
             Associ   Suite B                                marketing
             ation    Centenn                                plan
                      ial, CO
                      80112
------------------------------------------------------------------------
Monetary    New      P.O. Box          $1,500    12/8/2015  Fundraising
             Jersey   7683                                   event
             Capita   Trenton                                support to
             l        , NJ                                   benefit
             Philha   08628                                  general
             rmonic                                          mission of
             Orches                                          organizatio
             tra,                                            n
             Inc.
------------------------------------------------------------------------
Monetary    New      275 Rt.           $4,000     7/1/2015  NJPC
             Jersey   10 East                                Strengtheni
             Parent   Suite                                  ng Family
             s        220-414                                and Youth
             Caucus   Succasu                                Involvement
                      nna, NJ                                Conference
                      07876                                  and
                                                             Professiona
                                                             l Parent
                                                             Advocacy
                                                             Training
------------------------------------------------------------------------
Monetary    NewBrid  7                 $2,000    6/10/2015  NewBridge
             ge       Industr                                Day
             Servic   ial                                    Treatment
             es,      Road                                   Program for
             Inc.     Pequann                                Adults
                      ock, NJ
                      07440
------------------------------------------------------------------------
Monetary    Ohio     433                  $75     2/6/2015  Employee
             Great    Canal                                  directed
             Dane     Ct                                     donation in
             Rescue   Watervi                                lieu of
                      lle, OH                                company
                      43566                                  holiday
                                                             gift
------------------------------------------------------------------------
Monetary    Paralyz  2235                 $75     2/6/2015  Employee
             ed       Enterpr                                directed
             Vetera   ise                                    donation in
             ns of    Drive,                                 lieu of
             Americ   Suite                                  company
             a        3501                                   holiday
                      Westche                                gift
                      ster,
                      IL
                      60154
------------------------------------------------------------------------
Monetary    Parent   P.O. Box          $2,000    12/8/2015  Steinert
             Booste   3352                                   High
             r USA    Mercerv                                Robotics
             dba      ille,                                  FIRST FRC
             Steine   NJ                                     Team 2180
             rt       08690                                  Parents
             High                                            Association
             Roboti
             cs
             Parent
             s
             Associ
             ation
------------------------------------------------------------------------
Monetary    Partner  888              $10,700   12/15/2015  General
             s in     Commonw                                mission
             Health   ealth                                  support of
                      Ave,                                   organizatio
                      3rd                                    n
                      Floor
                      Boston,
                      MA
                      02215
------------------------------------------------------------------------
Monetary    Passage  PO Box            $5,000    12/8/2015  The State
             Theatr   967                                    Street
             e        Trenton                                Project
             Compan   , NJ
             y,       08608
             Inc.
------------------------------------------------------------------------
Monetary    PEI      231                 $300    8/27/2015  Costs
             Kids     Lawrenc                                associated
                      e Road                                 with 2015
                      Lawrenc                                Janssen
                      eville,                                Cares event
                      NJ
                      08648
------------------------------------------------------------------------
Monetary    PEI      231              $17,500   10/27/2015  Comprehensiv
             Kids     Lawrenc                                e Juvenile
                      e Road                                 Offenders
                      Lawrenc                                Outreach
                      eville,                                Services
                      NJ
                      08648
------------------------------------------------------------------------
Monetary    People   140 E             $2,500   11/16/2015  People and
             And      Hanover                                Stories
             Storie   Street                                 with Mercer
             s--Gen   Trenton                                County
             te Y     , NJ                                   Seniors
             Cuento   08608
             s,
             Inc.
------------------------------------------------------------------------
Monetary    Plansma  118 West          $3,500     6/4/2015  2015
             rt NJ    State                                  Corporate
                      PlanSma                                membership
                      rt NJ                                  renewal
                      Trenton                                donation to
                      , NJ                                   support
                      08608                                  efforts
                                                             around
                                                             sound land
                                                             use
                                                             planning
------------------------------------------------------------------------
Monetary    Princet  P.O. Box          $1,500   10/30/2015  Giving Voice
             on       145 190                                To
             Girl     Nassau                                 Communities
             Choir    Street,                                : PGC's
                      Lower                                  Music
                      Level                                  Afterschool
                      Princet                                Program
                      on, NJ
                      08542
------------------------------------------------------------------------
Monetary    Princet  78 LEIGH          $5,000   11/16/2015  PNS Role
             on       AVE                                    Models for
             Nurser   PRINCET                                Health
             y        ON, NJ
             School   08542
             , Inc.
------------------------------------------------------------------------
Monetary    Princet  123 E.           $12,500   12/15/2015  Hunger
             on       Hanover                                Prevention
             Outrea   St.                                    and
             ch       Trenton                                Nutrition
             Projec   , NJ                                   Education
             ts /     08608                                  ($7,500.00)
             Crisis                                          Healthy
             Minist                                          Living and
             ry of                                           Housing
             Mercer                                          Stability
             County                                          Services
                                                             ($5,000.00)
------------------------------------------------------------------------
Monetary    Princet  P.O. Box          $2,500    12/8/2015  Princeton
             on       250                                    Symphony
             Sympho   Princet                                Orchestra @
             ny       on, NJ                                 Isles Youth
             Orches   08542                                  Institute--
             tra                                             a series of
                                                             interactive
                                                             music
                                                             appreciatio
                                                             n programs
------------------------------------------------------------------------
Monetary    Princet  13                $7,500   11/16/2015  Princeton-
             on-      Roszel                                 Blairstown
             Blairs   Road,                                  Center's
             town     Suite                                  2015-16
             Center   C204A                                  Summer
             , Inc.   Princet                                Bridge
                      on, NJ                                 Program for
                      08540-                                 Mercer
                      7137                                   County At-
                                                             Risk Youth
------------------------------------------------------------------------
Monetary    Printma  440               $5,000    11/3/2015  Roving Press
             king     River
             Center   Road
             of New   Branchb
             Jersey   urg, NJ
                      08876
------------------------------------------------------------------------
Monetary    Printma  440              $15,000   11/24/2015  Combat paper
             king     River                                  of NJ
             Center   Road
             of New   Branchb
             Jersey   urg, NJ
                      08876
------------------------------------------------------------------------
Monetary    PTA New  171 Old           $3,000     8/5/2015  Fundraising
             Jersey   Turnpik                                event
             Congre   e Road                                 support to
             ss Of    Califon                                benefit
             Parent   , NJ                                   general
             s and    07830                                  mission of
             Teache                                          organizatio
             rs                                              n
------------------------------------------------------------------------
Monetary    Raritan  P.O. Box          $8,000    12/1/2015  WaterWays
             Headwa   273                                    Environment
             ters     Gladsto                                al
             Associ   ne, NJ                                 Education
             ation    07934                                  Program
------------------------------------------------------------------------
Monetary    Raritan  118              $20,000   11/24/2015  Promoting
             Valley   Lamingt                                Access to
             Commun   on Road                                STEM,
             ity      Branchb                                Nursing and
             Colleg   urg, NJ                                Community
             e        08844                                  Health
                                                             Education
                                                             at Raritan
                                                             Valley
                                                             Community
                                                             College
------------------------------------------------------------------------
Monetary    ReDisco  901 NE            $7,500    6/23/2015  Same-Day
             ver      Indepen                                Access to
                      dence                                  Care
                      Avenue                                 program
                      Lees
                      Summit,
                      MO
                      64086
------------------------------------------------------------------------
Monetary    Regions  640              $15,000    7/21/2015  Make It OK
             Hospit   Jackson                                Stigma
             al       Street,                                Campaign
             Founda   MS
             tion     11202C
                      St.
                      Paul,
                      MN
                      55101
------------------------------------------------------------------------
Monetary    Rescue   98                $5,000    1/14/2015  Fundraising
             Missio   Carroll                                event
             n of     Street,                                support to
             Trento   PO Box                                 benefit
             n        790                                    general
                      Trenton                                mission of
                      , NJ                                   organizatio
                      08605                                  n
------------------------------------------------------------------------
Monetary    Rescue   98               $25,000    10/2/2015  Emergency
             Missio   Carroll                                services
             n of     Street,                                program
             Trento   PO Box
             n        790
                      Trenton
                      , NJ
                      08605
------------------------------------------------------------------------
Monetary    Rider    2083             $20,000   11/24/2015  STEM
             Univer   Lawrenc                                Program;
             sity     eville                                 Janssen
                      Road                                   Science and
                      Lawrenc                                Business
                      eville,                                Scholarship
                      NJ                                     s;
                      08648                                  Shakesperia
                                                             n at Rider
------------------------------------------------------------------------
Monetary    Riverbe  3 N.              $5,000    5/22/2015  InSHAPE
             nd       State                                  Program
             Commun   Street,
             ity      PO Box
             Mental   2032
             Health   Concord
             , Inc.   , NH
                      03301
------------------------------------------------------------------------
Monetary    Riversi  4 South           $9,300   11/16/2015  Riverside
             de       Union                                  Symphonia
             Sympho   Street                                 Senior
             nia,     P.O.                                   Outreach
             Inc.     Box 650                                Program
                      Lambert
                      ville,
                      NJ
                      08530
------------------------------------------------------------------------
Monetary    San      445               $5,000    5/14/2015  Culinary,
             Antoni   Recolet                                Education
             o        a Rd.                                  and
             Clubho   San                                    Nutrition
             use,     Antonio                                Program--Nu
             Inc.     , TX                                   tritious
                      78216                                  meals,
                                                             culinary
                                                             training,
                                                             pre-
                                                             vocational
                                                             education,
                                                             employment
                                                             placement
------------------------------------------------------------------------
Monetary    San      2789-             $5,000    4/16/2015  MHRC Client
             Franci   25th                                   Wellness
             sco      Street,                                Enhancement
             Genera   #2028                                  Project
             l        PO Box
             Hospit   410836
             al       San
             Founda   Francis
             tion     co, CA
                      94110
------------------------------------------------------------------------
Monetary    SAVE A   900                 $300   10/13/2015  Costs
             Friend   Herront                                associated
             to       own                                    with 2015
             Homele   Road                                   Janssen
             ss       Princet                                Cares
             Animal   on, NJ                                 Volunteer
             s        08540                                  Event
------------------------------------------------------------------------
Monetary    Save     501              $66,700   12/22/2015  Support
             The      Kings                                  efforts to
             Childr   Highway                                give
             en       East,                                  children a
             U.S.     Suite                                  healthy
             Headqu   400                                    start, the
             arters   Fairfie                                opportunity
                      ld, CT                                 to learn
                      06825                                  and
                                                             protection
                                                             from harm
                                                             (child
                                                             protection,
                                                             education,
                                                             emergency
                                                             response,
                                                             health and
                                                             nutrition,
                                                             hunger and
                                                             livelihoods
                                                             , HIV and
                                                             AIDS)
------------------------------------------------------------------------
Monetary    Schizop  602 Pink          $2,500    7/16/2015  2015
             hrenia   Azalea                                 Conference,
             And      Trl PO                                 ``Schizophr
             Relate   Box                                    enia: It's
             d        941222                                 Global''
             Disord   Houston
             ers      , TX
             Allian   77094-
             ce Of    8222
             Americ   Houston
             a        , TX
                      77079-
                      1123
------------------------------------------------------------------------
Monetary    Scripps  10140            $30,000   12/23/2015  Dulce
             Founda   Campus                                 Prevention:
             tion     Point                                  A Diabetes
             for      Drive                                  Early
             Medici   Suite                                  Prevention
             ne and   200 San                                Program
             Scienc   Diego,
             e        CA
                      92121
------------------------------------------------------------------------
Monetary    Scripps  10140            $25,000   12/23/2015  Project
             Founda   Campus                                 Dulce
             tion     Point
             for      Drive
             Medici   Suite
             ne and   200 San
             Scienc   Diego,
             e        CA
                      92121
------------------------------------------------------------------------
Monetary    SERV     20                $7,500    9/22/2015  The SERV
             Founda   Scotch                                 Foundation
             tion,    Road,                                  Scholarship
             Inc.     3rd                                    Fund
                      Floor
                      Ewing,
                      NJ
                      08628
------------------------------------------------------------------------
Monetary    SERV     20                $5,000    9/22/2015  13th Annual
             Founda   Scotch                                 Recovery NJ
             tion,    Road,                                  Conference
             Inc.     3rd
                      Floor
                      Ewing,
                      NJ
                      08628
------------------------------------------------------------------------
Monetary    SERV     20                  $300    9/24/2015  Costs
             Founda   Scotch                                 associated
             tion,    Road,                                  with 2015
             Inc.     3rd                                    Janssen
                      Floor                                  Cares
                      Ewing,                                 Volunteer
                      NJ                                     event
                      08628
------------------------------------------------------------------------
Monetary    Shannon  PO Box              $500    12/1/2015  Shannon
             Daley    1271 36                                Daley
             Memori   Indian                                 Memorial
             al       Run                                    Fund
             Fund     Whiteho                                Charity
                      use                                    Events
                      Station
                      , NJ
                      08889
------------------------------------------------------------------------
Monetary    Sharing  1920              $2,000    5/22/2015  Art and
             Place,   10th                                   Music
             Inc.     Avenue                                 Program at
                      South                                  the 1920
                      PO Box                                 Club
                      55945
                      Birming
                      ham, AL
                      35255-
                      5945
------------------------------------------------------------------------
Monetary    Sister   1201              $6,500    10/6/2015  Fundraising
             Networ   Hamilto                                event
             k of     n                                      support to
             Centra   Street                                 benefit
             l New    Somerse                                general
             Jersey   t, NJ                                  mission of
             , Inc.   08873                                  organizatio
                                                             n
------------------------------------------------------------------------
Monetary    Sisters  1201              $1,000     2/6/2015  2015 Health
             Networ   Hamilto                                Summit and
             k of     n                                      Breakfast
             Centra   Street
             l New    Somerse
             Jersey   t, NJ
                      08873
------------------------------------------------------------------------
Monetary    Somerse  1810              $8,292    12/1/2015  Teaching
             t        Burnt                                  Social
             Hills    Mills                                  Skills
             Learni   Road
             ng       Bedmins
             Instit   ter, NJ
             ute      07921
------------------------------------------------------------------------
Monetary    Somerse  49                $1,250    1/20/2015  2014 Steps
             t Home   Brahma                                 for Giving
             for      Avenue,                                Program
             Tempor   P.O.
             arily    Box
             Displa   6871
             ced      Bridgew
             Childr   ater,
             en       NJ
                      08807-
                      0871
------------------------------------------------------------------------
Monetary    Somerse  49                $7,500    5/22/2015  Fundraising
             t Home   Brahma                                 event
             for      Avenue,                                support to
             Tempor   P.O.                                   benefit
             arily    Box                                    general
             Displa   6871                                   mission of
             ced      Bridgew                                organizatio
             Childr   ater,                                  n
             en       NJ
                      08807-
                      0871
------------------------------------------------------------------------
Monetary    Somerse  49                $7,500   11/25/2015  Street
             t Home   Brahma                                 Smart--HIV/
             for      Avenue,                                AIDS and
             Tempor   P.O.                                   STD
             arily    Box                                    Prevention
             Displa   6871
             ced      Bridgew
             Childr   ater,
             en       NJ
                      08807-
                      0871
------------------------------------------------------------------------
Monetary    St.      208                 $100    2/13/2015  Memorial
             France   Bound                                  donation
             s        Brook
             Cabrin   Avenue
             i        Piscata
             Church   way, NJ
                      08854
------------------------------------------------------------------------
Monetary    St.      One              $15,000    12/8/2015  Providing
             Mary     Summit                                 Food for
             Medica   Square,                                School-Age
             l        Suite                                  Children
             Center   300                                    Living in
             Founda   1717                                   Poverty in
             tion     Langhor                                Bucks
                      ne-                                    County: The
                      Newtown                                St. Mary
                      Road                                   Backpacks
                      Langhor                                for Kids
                      ne, PA                                 Program
                      19047
------------------------------------------------------------------------
Monetary    Stony    31 Titus         $15,000   11/13/2015  StreamWatch
             Brook    Mill                                   Volunteer
             Millst   Road                                   Water
             one      Penning                                Quality
             Waters   ton, NJ                                Monitoring
             hed      08534                                  Program
             Associ
             ation
------------------------------------------------------------------------
Monetary    T-1      8216             $35,000   11/25/2015  Type 2
             Today,   Princet                                Education
             Inc.     on-                                    for Type 1
                      Glendal                                Families
                      e Road,
                      PMB 200
                      West
                      Chester
                      , OH
                      45069
------------------------------------------------------------------------
Monetary    TASK,    72\1/2\             $300    6/23/2015  Costs
             Inc.     Escher                                 associated
                      Street,                                with 2015
                      P.O.                                   Janssen
                      Box 872                                Cares
                      Trenton                                Volunteer
                      , NJ                                   Activity
                      08605
------------------------------------------------------------------------
Monetary    TASK,    72\1/2\          $25,000    10/8/2015  Trenton Area
             Inc.     Escher                                 Soup
                      Street,                                Kitchen
                      P.O.                                   Meal
                      Box 872                                Service
                      Trenton                                Program
                      , NJ
                      08605
------------------------------------------------------------------------
Monetary    TASK,    72\1/2\          $20,700   12/15/2015  Support
             Inc.     Escher                                 hunger
                      Street,                                program in
                      P.O.                                   the Trenton
                      Box 872                                area,
                      Trenton                                programs to
                      , NJ                                   encourage
                      08605                                  self-
                                                             sufficiency
                                                             and improve
                                                             the quality
                                                             of life of
                                                             their
                                                             patrons
------------------------------------------------------------------------
Monetary    The      Paul              $5,000   11/13/2015  Communiversi
             Arts     Robeson                                ty ArtsFest
             Counci   Center                                 2016
             l of     for the
             Prince   Arts
             ton      102
                      Withers
                      poon
                      Street
                      Princet
                      on, NJ
                      08542
------------------------------------------------------------------------
Monetary    The      Paul             $10,000   11/16/2015  Community
             Arts     Robeson                                outreach
             Counci   Center                                 programs
             l of     for the                                for youth
             Prince   Arts                                   and seniors
             ton      102
                      Withers
                      poon
                      Street
                      Princet
                      on, NJ
                      08542
------------------------------------------------------------------------
Monetary    The      2020              $2,000    12/1/2015  ``Art for
             Center   Burnt                                  Children
             for      Mills                                  with Autism
             Contem   Road                                   Spectrum
             porary   Bedmins                                Disorder
             Art      ter, NJ                                and Special
                      07921                                  Needs''
------------------------------------------------------------------------
Monetary    The      19                  $300    8/19/2015  Costs
             Center   Dellwoo                                associated
             For      d Lane                                 with 2015
             Great    Somerse                                Janssen
             Expect   t, NJ                                  Cares
             ations   08873                                  Volunteer
                                                             Activity
------------------------------------------------------------------------
Monetary    The      19               $13,500   10/21/2015  Trauma-
             Center   Dellwoo                                informed,
             For      d Lane                                 residential
             Great    Somerse                                treatment
             Expect   t, NJ                                  for
             ations   08873                                  homeless,
                                                             pregnant/
                                                             parenting
                                                             adult women
                                                             in
                                                             substance
                                                             use
                                                             recovery,
                                                             and their
                                                             children.
------------------------------------------------------------------------
Monetary    The      1040              $5,000    6/23/2015  Jail
             Edinbu   Waltham                                Diversion
             rg       Street                                 Program
             Center   Lexingt
                      on, MA
                      02421
------------------------------------------------------------------------
Monetary    The      8150 N.          $40,000    12/4/2015  VTE
             Mended   Central                                Education
             Hearts   Express                                and
             , Inc.   way,                                   Outreach
                      Suite                                  Program
                      M2248
                      Dallas,
                      TX
                      75206
------------------------------------------------------------------------
Monetary    The      401                 $500     3/2/2015  Flash Lite
             Mental   Cypress                                sponsor
             Health   Street                                 2015 Lite
             Center   Manches                                up the Nite
             Of       ter, NH                                for Mental
             Greate   03103                                  Health Run/
             r                                               Walk
             Manche
             ster
------------------------------------------------------------------------
Monetary    The      P.O. Box          $7,500   11/16/2015  Arts
             Prince   2063                                   education
             ton      Princet                                and
             Festiv   on, NJ                                 community
             al       08543                                  engagement
                                                             programs
------------------------------------------------------------------------
Monetary    Thomas   101 West         $12,000   11/13/2015  Scholarships
             Edison   State                                  for
             State    Street                                 Students
             Colleg   Trenton                                Enrolled in
             e        , NJ                                   the
             Founda   08608                                  Accelerated
             tion                                            Second
                                                             Degree BSN
                                                             Program at
                                                             Thomas
                                                             Edison
                                                             State
                                                             College's
                                                             W. Cary
                                                             Edwards
                                                             School of
                                                             Nursing
------------------------------------------------------------------------
Monetary    TPTO     51 South          $1,000   11/16/2015  2016
             Inc--T   Timberl                                Timberlane
             imberl   ane                                    Science and
             ane      Drive,                                 Engineering
             Parent   Penning                                Fair
             Teache   ton NJ
             r        08534
             Organi   Penning
             zation   ton, NJ
                      08534
------------------------------------------------------------------------
Monetary    Trenton  P.O. Box          $5,000   11/12/2015  Trenton
             Commun   5206                                   Community
             ity      (physic                                Music
             Music    al                                     School
             School   address                                Community-
                      : 439                                  Based Music
                      S.                                     Education
                      Broad
                      Street,
                      Ste.
                      90,
                      Trenton
                      NJ
                      08611
                      Trenton
                      , NJ
                      08638
------------------------------------------------------------------------
Monetary    Trenton  635               $3,500   11/16/2015  Trenton
             Educat   South                                  Education
             ion      Clinton                                Dance
             Dance    Avenue                                 Institute
             Instit   Trenton                                program for
             ute      , NJ                                   at-risk
                      08611                                  youth in
                                                             Trenton
------------------------------------------------------------------------
Monetary    Trenton  218 N            $15,000   10/23/2015  Further
             Health   Broad                                  Inroads for
             Team,    St                                     Health
             Inc.     Trenton
                      , NJ
                      08608
------------------------------------------------------------------------
Monetary    Trinity  22                $7,500   11/12/2015  Mental
             Counse   Stockto                                Health and
             ling     n                                      Wellness
             Servic   Street                                 Programs
             es       Trinity
                      Counsel
                      ing
                      Service
                      Princet
                      on, NJ
                      08540
------------------------------------------------------------------------
Monetary    Twiligh  P.O. Box          $7,500   11/16/2015  Simple Needs
             t Wish   1042 11                                Wish
             Founda   Duane                                  Granting
             tion     Road                                   Program
                      Doylest
                      own, PA
                      18901
------------------------------------------------------------------------
Monetary    UIH      4 North           $7,500    9/28/2015  Community of
             Family   Broad                                  Health for
             Partne   Street                                 Men Program
             rs       2nd                                    (Year 2)
                      Floor
                      Trenton
                      , NJ
                      08618-
                      4408
------------------------------------------------------------------------
Monetary    United   9-25              $7,500    9/25/2015  Princeton
             Negro    Alling                                 Committee
             Colleg   Street                                 of UNCF
             e Fund   2nd                                    Scholarship
                      Floor
                      Newark,
                      NJ
                      07102
------------------------------------------------------------------------
Monetary    United   Attn:           $595,877   12/21/2015  Company
             Way      Finance                                match to
             Worldw   Operati                                employee
             ide      on P.O.                                United Way
                      Box                                    campaign
                      418607                                 for NJ
                      Boston,                                based
                      MA                                     commercial
                      02241-                                 companies
                      8607                                   of Janssen
                                                             Pharmaceuti
                                                             cal
                                                             Companies
                                                             of Johnson
                                                             & Johnson
------------------------------------------------------------------------
Monetary    Valeo    5401 SW           $3,500    5/22/2015  Creations of
             Behavi   7th                                    Hope: A
             oral     Street                                 gallery by
             Health   Topeka,                                artists
             Care,    KS                                     experiencin
             Inc.     66606                                  g mental
                                                             illness
------------------------------------------------------------------------
Monetary    Volunte  12                $7,500   11/12/2015  SkillsConnec
             er       Stockto                                t program
             Connec   n
             t        Street
                      Princet
                      on, NJ
                      08540
------------------------------------------------------------------------
Monetary    Washing  P.O. Box            $500    2/27/2015  Educational
             ton      83                                     program
             Crossi   Titusvi                                focused on
             ng       lle, NJ                                New Jersey
             Park     08560                                  in the
             Associ                                          American
             ation,                                          Revolutiona
             Inc.                                            ry War
------------------------------------------------------------------------
Monetary    We Care  3035              $1,500    6/22/2015  Support
             Arts     Wilming                                Artowork
                      ton                                    program,
                      Pike                                   which aims
                      Ketteri                                to use art
                      ng, OH                                 to help
                      45429                                  enrich
                                                             lives of
                                                             the
                                                             mentally
                                                             ill
------------------------------------------------------------------------
Monetary    West     120                 $300    8/20/2015  Costs
             Bergen   Chestnu                                associated
             Mental   t                                      with 2015
             Health   Street                                 Janssen
             care     Ridgewo                                Cares
                      od, NJ                                 Volunteer
                      07450-                                 Activity
                      2500
------------------------------------------------------------------------
Monetary    West     PO Box            $5,000   11/12/2015  Excellence
             Windso   280                                    in
             r        West                                   Education
             Plains   Windsor                                Grant
             boro     , NJ                                   Program
             Educat   08550-
             ion      0280
             Founda
             tion
------------------------------------------------------------------------
Monetary    Womansp  1530                $300    6/26/2015  Costs
             ace      Brunswi                                associated
                      ck Ave.                                with 2015
                      Lawrenc                                Janssen
                      eville,                                Cares
                      NJ                                     Volunteer
                      08648                                  Activity
------------------------------------------------------------------------
Monetary    Women's  3200                 $75    1/14/2015  Employee
             Commun   Hilltop                                directed
             ity,     Avenue                                 donation in
             Inc.     Wausau,                                lieu of
                      WI                                     company
                      54401                                  holiday
                                                             gift
------------------------------------------------------------------------
Monetary    Woods    40                $4,000   11/20/2015  Improving
             Servic   Martin                                 the Health
             es       Gross                                  of People
             Founda   Drive                                  with
             tion     PO box                                 Disabilitie
                      36                                     s at Woods
                      Langhor                                Services
                      ne, PA                                 through
                      19047                                  Enhanced
                                                             Recreationa
                                                             l
                                                             Activities
------------------------------------------------------------------------
Monetary    YMCA of  431               $5,000   11/16/2015  Science in
             Trento   Penning                                the City--
             n        ton                                    Minorities
                      Avenue                                 in M.I.N.T.
                      Trenton                                Mentoring
                      , NJ                                   Program
                      08618
------------------------------------------------------------------------
Monetary    Young    349 W.              $300    7/14/2015  Costs
             Schola   State                                  associated
             rs'      St                                     with 2015
             Instit   Trenton                                Janssen
             ute      , NJ                                   Cares
                      08618                                  Volunteer
                                                             Activity
------------------------------------------------------------------------
Monetary    Zufall   18 West             $300     8/3/2015  Costs
             Health   Blackwe                                associated
             Center   ll                                     with 2015
             , Inc.   Street                                 Janssen
                      Dover,                                 Cares
                      NJ                                     Volunteer
                      07801                                  Activity
------------------------------------------------------------------------
Product     AmeriCa  88            $6,802,406    3/10/2015  Product
             res      Hamilto                                donation
             Founda   n Ave                                  for
             tion     Stamfor                                humanitaria
                      d, CT                                  n
                      06902                                  assistance
                                                             in
                                                             Afghanistan
                                                             , Armenia,
                                                             Dominican
                                                             Republic,
                                                             Gaza,
                                                             Ghana,
                                                             Honduras,
                                                             Nicaragua,
                                                             Peru, US,
                                                             West Bank
------------------------------------------------------------------------
Product     AmeriCa  88              $413,439    3/10/2015  Product
             res      Hamilto                                donation
             Founda   n Ave                                  for
             tion     Stamfor                                humanitaria
                      d, CT                                  n
                      06902                                  assistance
                                                             in
                                                             Dominican
                                                             Republic,
                                                             Nicaragua,
                                                             Peru, US,
                                                             West Bank
------------------------------------------------------------------------
Product     AmeriCa  88              $292,148     4/2/2015  Product
             res      Hamilto                                donation
             Founda   n Ave                                  for
             tion     Stamfor                                humanitaria
                      d, CT                                  n
                      06902                                  assistance
                                                             in Armenia,
                                                             Columbia,
                                                             Dominican
                                                             Republic,
                                                             Gaza,
                                                             Lebanon,
                                                             Nicaragua,
                                                             West Bank
------------------------------------------------------------------------
Product     AmeriCa  88              $219,598    4/30/2015  Product
             res      Hamilto                                donation
             Founda   n Ave                                  for
             tion     Stamfor                                humanitaria
                      d, CT                                  n
                      06902                                  assistance
                                                             in Nepal
                                                             (2015
                                                             earthquake
                                                             relief)
------------------------------------------------------------------------
Product     AmeriCa  88              $673,887     5/5/2015  Product
             res      Hamilto                                donation
             Founda   n Ave                                  for
             tion     Stamfor                                humanitaria
                      d, CT                                  n relief in
                      06902                                  Lebanon
                                                             (ANERA
                                                             program)
------------------------------------------------------------------------
Product     AmeriCa  88              $279,339    5/20/2015  Product
             res      Hamilto                                donation
             Founda   n Ave                                  for
             tion     Stamfor                                humanitaria
                      d, CT                                  n relief in
                      06902                                  Romania,
                                                             Senegal,
                                                             United
                                                             States
------------------------------------------------------------------------
Product     AmeriCa  88            $1,454,074     6/4/2015  Product
             res      Hamilto                                donation
             Founda   n Ave                                  for
             tion     Stamfor                                humanitaria
                      d, CT                                  n
                      06902                                  assistance
                                                             in Lebanon,
                                                             West Bank,
                                                             US,
                                                             Tanzania,
                                                             Peru,
                                                             Afghanistan
                                                             , Colombia,
                                                             Malawi,
                                                             Armenia
------------------------------------------------------------------------
Product     AmeriCa  88            $6,800,452    6/29/2015  Product
             res      Hamilto                                donation
             Founda   n Ave                                  for
             tion     Stamfor                                humanitaria
                      d, CT                                  n
                      06902                                  assistance
                                                             in Gaza,
                                                             West Bank,
                                                             US
------------------------------------------------------------------------
Product     AmeriCa  88               $13,984     8/3/2015  Product
             res      Hamilto                                donation
             Founda   n Ave                                  for
             tion     Stamfor                                humanitaria
                      d, CT                                  n
                      06902                                  assistance
                                                             in
                                                             Nicaragua
------------------------------------------------------------------------
Product     AmeriCa  88           $54,149,760     8/6/2015  Product
             res      Hamilto                                donation
             Founda   n Ave                                  for
             tion     Stamfor                                humanitaria
                      d, CT                                  n
                      06902                                  assistance
                                                             in Armenia,
                                                             Uzbekistan,
                                                             US
------------------------------------------------------------------------
Product     AmeriCa  88               $84,124     9/9/2015  Product
             res      Hamilto                                donation
             Founda   n Ave                                  for
             tion     Stamfor                                humanitaria
                      d, CT                                  n
                      06902                                  assistance:
                                                             disaster
                                                             relief
                                                             preparednes
                                                             s
------------------------------------------------------------------------
Product     AmeriCa  88            $2,921,081    10/5/2015  Product
             res      Hamilto                                donation
             Founda   n Ave                                  for
             tion     Stamfor                                humanitaria
                      d, CT                                  n
                      06902                                  assistance
                                                             in
                                                             Honduras,
                                                             Peru,
                                                             Armenia,
                                                             Tanzania,
                                                             Senegal,
                                                             Afghanistan
                                                             and for
                                                             disaster
                                                             preparednes
                                                             s modules
------------------------------------------------------------------------
Product     AmeriCa  88            $1,544,676    10/5/2015  Product
             res      Hamilto                                donation
             Founda   n Ave                                  for
             tion     Stamfor                                humanitaria
                      d, CT                                  n
                      06902                                  assistance
                                                             in
                                                             Afghanistan
                                                             , Armenia,
                                                             Gaza, Peru,
                                                             Senegal,
                                                             Tanzania,
                                                             West Bank,
                                                             US
------------------------------------------------------------------------
Product     AmeriCa  88              $456,654    11/4/2015  Product
             res      Hamilto                                donation
             Founda   n Ave                                  for
             tion     Stamfor                                humanitaria
                      d, CT                                  n
                      06902                                  assistance
                                                             in Armenia,
                                                             Gaza, Peru,
                                                             Romania,
                                                             Senegal,
                                                             Uzbekistan,
                                                             West Bank
------------------------------------------------------------------------
Product     AmeriCa  88            $1,070,880   11/18/2015  Product
             res      Hamilto                                donation
             Founda   n Ave                                  for
             tion     Stamfor                                humanitaria
                      d, CT                                  n
                      06902                                  assistance
                                                             in
                                                             Guatemala
------------------------------------------------------------------------
Product     AmeriCa  88              $897,021    12/8/2015  Product
             res      Hamilto                                donation
             Founda   n Ave                                  for
             tion     Stamfor                                humanitaria
                      d, CT                                  n
                      06902                                  assistance
                                                             in Armenia,
                                                             Nicaragua,
                                                             Peru, US
------------------------------------------------------------------------
Product     AmeriCa  88               $48,945   12/21/2015  Product
             res      Hamilto                                donation
             Founda   n Ave                                  for
             tion     Stamfor                                humanitaria
                      d, CT                                  n
                      06902                                  assistance
                                                             in USA
------------------------------------------------------------------------
Product     AmeriCa  88            $2,005,526   12/21/2015  Product
             res      Hamilto                                donation
             Founda   n Ave                                  for
             tion     Stamfor                                humanitaria
                      d, CT                                  n
                      06902                                  assistance
                                                             in USA
------------------------------------------------------------------------
Product     Catholi  100 Wall        $812,025    3/10/2015  Product
             c        Street,                                donation
             Medica   9th                                    for
             l        Floor                                  humanitaria
             Missio   New                                    n
             n        York,                                  assistance
             Board    NY                                     in Haiti,
                      10005                                  Honduras,
                                                             Jamaica,
                                                             Nicaragua
------------------------------------------------------------------------
Product     Catholi  100 Wall        $105,683    3/10/2015  Product
             c        Street,                                donation
             Medica   9th                                    for
             l        Floor                                  humanitaria
             Missio   New                                    n
             n        York,                                  assistance
             Board    NY                                     in Haiti,
                      10005                                  Jamaica
------------------------------------------------------------------------
Product     Catholi  33-01           $275,375     6/4/2015  Product
             c        Elevent                                donation
             Medica   h                                      for
             l        Street                                 humanitaria
             Missio   Long                                   n
             n        Island                                 assistance
             Board    City,                                  in Jamaica,
                      NY                                     Armenia,
                                                             Guatemala
------------------------------------------------------------------------
Product     Catholi  33-01           $313,574    6/29/2015  Product
             c        Elevent                                donation
             Medica   h                                      for
             l        Street                                 humanitaria
             Missio   Long                                   n
             n        Island                                 assistance
             Board    City,                                  in El
                      NY                                     Salvador
------------------------------------------------------------------------
Product     Catholi  100 Wall      $1,612,989    10/9/2015  Product
             c        Street,                                donation
             Medica   9th                                    for
             l        Floor                                  humanitaria
             Missio   New                                    n
             n        York,                                  assistance
             Board    NY                                     in
                      10005                                  Guatemala,
                                                             Honduras,
                                                             Haiti
------------------------------------------------------------------------
Product     Catholi  100 Wall        $563,598    10/9/2015  Product
             c        Street,                                donation
             Medica   9th                                    for
             l        Floor                                  humanitaria
             Missio   New                                    n
             n        York,                                  assistance
             Board    NY                                     in
                      10005                                  Guatemala,
                                                             Honduras,
                                                             Haiti
------------------------------------------------------------------------
Product     Catholi  33-01             $8,754    11/4/2015  Product
             c        Elevent                                donation
             Medica   h                                      for
             l        Street                                 humanitaria
             Missio   Long                                   n
             n        Island                                 assistance
             Board    City,                                  in
                      NY                                     Dominican
                                                             Republic,
                                                             El
                                                             Salvador,
                                                             Guyana,
                                                             Nicaragua
------------------------------------------------------------------------
Product     Catholi  33-01           $343,347   12/18/2015  Product
             c        Elevent                                donation
             Medica   h                                      for
             l        Street                                 humanitaria
             Missio   Long                                   n
             n        Island                                 assistance
             Board    City,                                  in El
                      NY                                     Salvador,
                                                             Dominican
                                                             Republic,
                                                             Sierra
                                                             Leone,
                                                             Uganda,
                                                             Guatemala,
                                                             Guyana,
                                                             Philippines
------------------------------------------------------------------------
Product     Direct   27 S. La      $2,014,130    3/10/2015  Pharmaceutic
             Relief   Patera                                 al Product
                      Lane                                   Donation
                      Goleta,                                for
                      CA                                     Humanitaria
                      93117                                  n Aid in
                                                             Dominican
                                                             Republic,
                                                             El
                                                             Salvador,
                                                             Guatemala,
                                                             Haiti, US
------------------------------------------------------------------------
Product     Direct   27 S. La        $274,761    3/10/2015  Product
             Relief   Patera                                 donation
                      Lane                                   for
                      Goleta,                                humanitaria
                      CA                                     n
                      93117                                  assistance
                                                             in
                                                             Dominican
                                                             Republic,
                                                             Ghana,
                                                             Guatemala,
                                                             Nicaragua,
                                                             US
------------------------------------------------------------------------
Product     Direct   27 S. La         $17,185     4/2/2015  Pharmaceutic
             Relief   Patera                                 al Product
                      Lane                                   Donation
                      Goleta,                                for
                      CA                                     Humanitaria
                      93117                                  n Aid in
                                                             Paraguay
------------------------------------------------------------------------
Product     Direct   27 S. La         $13,131     5/4/2015  Product
             Relief   Patera                                 donation
                      Lane                                   for
                      Goleta,                                humanitaria
                      CA                                     n
                      93117                                  assistance
                                                             in Nepal
                                                             (2015
                                                             earthquake
                                                             relief)
------------------------------------------------------------------------
Product     Direct   27 S. La         $10,680     5/5/2015  Product
             Relief   Patera                                 donation
                      Lane                                   for
                      Goleta,                                humanitaria
                      CA                                     n
                      93117                                  assistance
                                                             in Congo,
                                                             Malawi,
                                                             Mali,
                                                             Somalia,
                                                             Tanzania,
                                                             Zambia
                                                             (obstetric
                                                             fistula
                                                             program)
------------------------------------------------------------------------
Product     Direct   27 S. La        $187,713    5/20/2015  Product
             Relief   Patera                                 donation
                      Lane                                   for
                      Goleta,                                humanitaria
                      CA                                     n relief in
                      93117                                  El
                                                             Salvador,
                                                             Guatemala,
                                                             Dominican
                                                             Republic,
                                                             United
                                                             States
------------------------------------------------------------------------
Product     Direct   27 S. La        $852,327     6/4/2015  Product
             Relief   Patera                                 donation
                      Lane                                   for
                      Goleta,                                humanitaria
                      CA                                     n
                      93117                                  assistance
                                                             in
                                                             Paraguay,
                                                             El
                                                             Salvador,
                                                             Nicaragua
------------------------------------------------------------------------
Product     Direct   27 S. La      $9,636,065    6/29/2015  Product
             Relief   Patera                                 donation
                      Lane                                   for
                      Goleta,                                humanitaria
                      CA                                     n
                      93117                                  assistance
                                                             in Haiti,
                                                             India,
                                                             Jamaica,
                                                             Paraguay,
                                                             Armenia,
                                                             Dominican
                                                             Republic,
                                                             Ghana,
                                                             Guatemala,
                                                             Hondorus,
                                                             US
------------------------------------------------------------------------
Product     Direct   27 S. La         $20,976     8/4/2015  Product
             Relief   Patera                                 donation
                      Lane                                   for
                      Goleta,                                humanitaria
                      CA                                     n
                      93117                                  assistance
                                                             in Paraguay
------------------------------------------------------------------------
Product     Direct   27 S. La         $13,878     8/5/2015  Product
             Relief   Patera                                 donation
                      Lane                                   for
                      Goleta,                                humanitaria
                      CA                                     n
                      93117                                  assistance
                                                             in Africa
------------------------------------------------------------------------
Product     Direct   27 S. La        $198,318    9/11/2015  Product
             Relief   Patera                                 donation
                      Lane                                   for
                      Goleta,                                humanitaria
                      CA                                     n
                      93117                                  assistance:
                                                             disaster
                                                             relief
                                                             preparednes
                                                             s
------------------------------------------------------------------------
Product     Direct   27 S. La      $5,543,118   10/12/2015  Product
             Relief   Patera                                 donation
                      Lane                                   for
                      Goleta,                                humanitaria
                      CA                                     n
                      93117                                  assistance
                                                             in
                                                             Nicaragua,
                                                             Sierra
                                                             Leone,
                                                             Ghana, US
                                                             and for
                                                             disaster
                                                             preparednes
                                                             s modules
------------------------------------------------------------------------
Product     Direct   27 S. La        $918,456   10/12/2015  Product
             Relief   Patera                                 donation
                      Lane                                   for
                      Goleta,                                humanitaria
                      CA                                     n
                      93117                                  assistance
                                                             in Ghana,
                                                             Sierra
                                                             Leone,
                                                             Nicaragua,
                                                             US
------------------------------------------------------------------------
Product     Direct   27 S. La         $81,702    11/4/2015  Product
             Relief   Patera                                 donation
                      Lane                                   for
                      Goleta,                                humanitaria
                      CA                                     n
                      93117                                  assistance
                                                             in
                                                             Cambodia,
                                                             Guatemala,
                                                             Haiti,
                                                             Honduras,
                                                             India,
                                                             Paraguay
------------------------------------------------------------------------
Product     Direct   27 S. La         $27,755   11/25/2015  Product
             Relief   Patera                                 donation
                      Lane                                   for
                      Goleta,                                humanitaria
                      CA                                     n
                      93117                                  assistance
                                                             in Africa
                                                             (obstetric
                                                             fistula
                                                             program)
------------------------------------------------------------------------
Product     Direct   27 S. La        $186,387    12/7/2015  Product
             Relief   Patera                                 donation
                      Lane                                   for
                      Goleta,                                humanitaria
                      CA                                     n
                      93117                                  assistance
                                                             in Ecuador,
                                                             Ghana,
                                                             Mexico,
                                                             Jamaica
------------------------------------------------------------------------
Product     Heart    13250 W       $4,874,474    10/6/2015  Product
             To       98th                                   donation
             Heart    Street                                 for
             Intern   Lenexa,                                humanitaria
             ationa   KS                                     n
             l        66215                                  assistance
                                                             in
                                                             Dominican
                                                             Republic,
                                                             Papua New
                                                             Guinea
------------------------------------------------------------------------
Product     Heart    13250 W       $1,148,070    10/6/2015  Product
             To       98th                                   donation
             Heart    Street                                 for
             Intern   Lenexa,                                humanitaria
             ationa   KS                                     n
             l        66215                                  assistance
                                                             in
                                                             Dominican
                                                             Republic
------------------------------------------------------------------------
Product     Johnson  One         $299,754,483   12/31/2015  Patient
             &        Johnson                                Assistance
             Johnso   &                                      Product
             n        Johnson                                Donation
             Patien   Plaza
             t        New
             Assist   Brunswi
             ance     ck, NJ
             Founda   08933
             tion
------------------------------------------------------------------------
Product     MAP      4700          $2,230,112    2/20/2015  Pharmaceutic
             Intern   Glynco                                 al Product
             ationa   Parkway                                Donation to
             l        Brunswi                                support the
                      ck, GA                                 Medical
                      31525                                  Mission
                                                             Pack+
                                                             Program
------------------------------------------------------------------------
Product     MAP      4700          $1,312,483    7/20/2015  Global
             Intern   Glynco                                 Public
             ationa   Parkway                                Health
             l        Brunswi                                programs in
                      ck, GA                                 Sub Saharan
                      31525                                  Africa
                                                             (HIV)
------------------------------------------------------------------------
Product     MAP      4700             $46,453    9/11/2015  Product
             Intern   Glynco                                 donations
             ationa   Parkway                                for
             l        Brunswi                                humanitaria
                      ck, GA                                 n
                      31525                                  assistance:
                                                             Medical
                                                             Mission
                                                             Pack Plus
                                                             replenishme
                                                             nt
------------------------------------------------------------------------
Product     MAP      4700             $35,015   11/25/2015  Product
             Intern   Glynco                                 donation
             ationa   Parkway                                for
             l        Brunswi                                humanitaria
                      ck, GA                                 n
                      31525                                  assistance
                                                             and medical
                                                             mission
                                                             pack +
                                                             program
------------------------------------------------------------------------
Product     MAP      4700            $951,077   12/15/2015  Product
             Intern   Glynco                                 donation
             ationa   Parkway                                for
             l        Brunswi                                humanitaria
                      ck, GA                                 n
                      31525                                  assistance
                                                             (medical
                                                             mission
                                                             pack +
                                                             program)
------------------------------------------------------------------------
Product     US       1300 PA      $29,310,000   12/17/2015  Global
             Agency   Avenue.                                Public
             for      , NW,                                  Health
             Intern   SA-44                                  programs--B
             ationa   Rm 475-                                edaquiline
             l        J                                      Donation
             Develo   Washing                                Program
             pment    ton, DC
                      20523
------------------------------------------------------------------------
Updated March 24, 2016


  Janssen Therapeutics, Division of Janssen Products, LP, Monetary and
 Product Contributions to U.S.-based Charitable Organizations Full Year
                                  2015
        (Payments made from January 1, 2015 to December 31, 2015)
------------------------------------------------------------------------
                                                               Project
 Donation    Payee     Payee   Payment Amount    Payment       Title/
   Type               Address       (USD)          Date      Description
------------------------------------------------------------------------
Monetary    Aboundi  2311              $5,000     5/8/2015  Project
             ng       Martin                                 CONNECT
             Prospe   Luther
             rty,     King
             Inc.     Blvd
                      Dallas,
                      TX
                      75215
------------------------------------------------------------------------
Monetary    Aboundi  2311             $15,000   11/13/2015  Confidential
             ng       Martin                                 and Mature
             Prospe   Luther                                 Explanation
             rty,     King                                   s (C-ME):
             Inc.     Blvd                                   HCV
                      Dallas,                                Awareness
                      TX                                     for At-Risk
                      75215                                  Adults in
                                                             South
                                                             Dallas
------------------------------------------------------------------------
Monetary    Aboundi  2311             $30,000   12/22/2015  Project TEST
             ng       Martin
             Prospe   Luther
             rty,     King
             Inc.     Blvd
                      Dallas,
                      TX
                      75215
------------------------------------------------------------------------
Monetary    Acercam  827               $7,000     5/8/2015  ContraSIDA
             iento    Wildwoo                                (Againsts
             Hispan   d Ave,                                 AIDS)
             o de     Suite
             Caroli   200
             na del   Columbi
             Sur      a, SC
                      29203
------------------------------------------------------------------------
Monetary    ADAP     PO Box            $5,000    3/16/2015  ADAP
             Advoca   15275                                  Directory
             cy       Physica
                      l:312
                      11th
                      Avenue,
                      #21g,
                      New
                      York,
                      NY
                      10001
                      Washing
                      ton, DC
                      20003
------------------------------------------------------------------------
Monetary    Aid For  515              $10,000    7/13/2015  Case
             AIDS     Greenwi                                Management
             Intern   ch St                                  Program
             ationa   New
             l,       York,
             Inc.     NY
                      10013
------------------------------------------------------------------------
Monetary    AID      811              $18,259   12/22/2015  Project
             Upstat   Pendlet                                Healthy
             e        on                                     Pink Parts
                      Street
                      Bldg.
                      #10
                      Greenvi
                      lle, SC
                      29601
------------------------------------------------------------------------
Monetary    AIDS     75 Amory         $15,000   11/13/2015  Viral
             Action   Street                                 Hepatitis
             Commit   Boston,                                Access to
             tee of   MA                                     Care
             Massac   02119                                  Project:
             husett                                          Access to
             s                                               treatment
------------------------------------------------------------------------
Monetary    AIDS     995               $5,000    7/27/2015  Bridges
             Care     Northwe                                Project
             Servic   st
             e,       Bouleva
             Inc.     rd
                      Winston
                      Salem,
                      NC
                      27101
------------------------------------------------------------------------
Monetary    AIDS     575 8th          $20,000    7/13/2015  HIV Health
             Commun   Ave,                                   Literacy
             ity      Suite                                  Education
             Resear   502 New                                and
             ch       York,                                  Training
             Initia   NY                                     for Service
             tive     10018                                  Providers
             of                                              Working
             Americ                                          with
             a                                               Vulnerable
             ACRIA                                           Populations
------------------------------------------------------------------------
Monetary    AIDS     6260              $3,000    5/27/2015  Supportive
             Founda   Westpar                                Services
             tion     k Drive
             Housto   Suite
             n,       100
             Inc.     Houston
                      , TX
                      77057
------------------------------------------------------------------------
Monetary    AIDS     200 W.           $40,000    5/20/2015  Road to
             Founda   Jackson                                Health:
             tion     Blvd.,                                 Promoting
             of       Suite                                  Successful
             Chicag   2100                                   Implementat
             o        Chicago                                ion of
                      , IL                                   Health Care
                      60606                                  Reform for
                                                             People
                                                             Living with
                                                             HIV/AIDS in
                                                             Illinois
------------------------------------------------------------------------
Monetary    AIDS     400 N             $5,000    3/12/2015  Case
             Outrea   Beach                                  Management
             ch       Street,                                Program for
             Center   Suite                                  People
                      100 Ft.                                Living with
                      Worth,                                 HIV
                      TX
                      76111
------------------------------------------------------------------------
Monetary    AIDS     1320             $28,020   12/22/2015  Transcend
             Projec   Webster
             t of     Street
             the      oakland
             East     , CA
             Bay      96612
------------------------------------------------------------------------
Monetary    AIDS     1424 K          $150,000   11/17/2015  Disseminatio
             United   Street,                                n of Access
                      NW,                                    to Care and
                      Ste.                                   Retention
                      200                                    in Care
                      Washing                                Best
                      ton, DC                                Practices
                      20005
------------------------------------------------------------------------
Monetary    AIDS     Box 3068          $5,000    3/13/2015  Latino
             Walk     San                                    Services
             San      Diego,
             Diego    CA
                      92163
------------------------------------------------------------------------
Monetary    Alexian  825 W.            $5,000    7/15/2015  Transitional
             Brothe   Welling                                Living
             rs       ton                                    Program for
             Bonave   Chicago                                Homeless
             nture    , IL                                   Adults with
             House    60657                                  HIV/AIDS
                                                             Case
                                                             Management
                                                             Services
------------------------------------------------------------------------
Monetary    Alivene  3808              $5,000    5/27/2015  Health and
             ss       Nicolle                                Wellness
             Projec   t Ave                                  Program:
             t,       Minneap                                Aging with
             Inc.     olis,                                  HIV/AIDS
                      MN
                      55409
------------------------------------------------------------------------
Monetary    Allianc  825               $3,000    5/27/2015  Nurse Case
             e For    Colorad                                Management
             Housin   o                                      for
             g And    Blvd.,                                 Residential
             Healin   Suite                                  Care
             g        100 Los                                Facility
                      Angeles                                Serving
                      , CA                                   Homeless
                      90041                                  Persons
                                                             with HIV/
                                                             AIDS
------------------------------------------------------------------------
Monetary    Atlanta  P.O. Box         $32,000    4/16/2015  Comprehensiv
             Harm     92670                                  e HIV and
             Reduct   Atlanta                                HCV
             ion      , GA                                   treatment
             Coalit   30314                                  for IDUs
             ion
------------------------------------------------------------------------
Monetary    BASIC    432               $5,000    5/15/2015  Fully
             NWFL,    Magnoli                                Committed
             INC.     a
                      Avenue
                      Panama
                      City,
                      FL
                      32401
------------------------------------------------------------------------
Monetary    BASIC    432              $29,250   12/22/2015  FULLY
             NWFL,    Magnoli                                COMMITTED:
             INC.     a                                      Improving
                      Avenue                                 Linkage to
                      Panama                                 Care and
                      City,                                  Retention
                      FL                                     among Young
                      32401                                  MSM of
                                                             Color
                                                             Living with
                                                             HIV
------------------------------------------------------------------------
Monetary    Bay      701 Oak           $5,000   12/21/2015  Patient Peer
             Area     Street                                 Navigation
             Young    San
             Positi   Francis
             ves      co, CA
                      94117
------------------------------------------------------------------------
Monetary    Brockto  500               $5,000    3/24/2015  HIV/AIDS
             n Area   Belmont                                Case
             Multi-   Street                                 Management
             Servic   Ste 300                                Initiative
             es,      Brockto                                and
             Inc.     n, MA                                  Hepatitis C
                      02301                                  Support
                                                             Group.
------------------------------------------------------------------------
Monetary    Bronx    540 East         $40,000    3/10/2015  Improving
             AIDS     Fordham                                Care and
             Servic   Rd                                     Treatment
             es,      Bronx,                                 for People
             Inc.     NY                                     who Inject
                      10458                                  Drugs
                                                             (PWID) who
                                                             are Living
                                                             with HIV
                                                             and/or
                                                             Hepatitis C
------------------------------------------------------------------------
Monetary    Caring   PO Box           $40,000    5/20/2015  Hepatitis C
             Ambass   1748                                   Program
             adors    Oregon                                 Support
             Progra   City,
             m,       OR
             Inc.     97045
------------------------------------------------------------------------
Monetary    Center   900              $25,000    3/10/2015  Hepatitis
             for      Avila                                  and HIV
             Health   Street,                                Navigation
             Justic   Suite                                  Project--RF
             e        301,                                   A
                      Los
                      Angeles
                      , CA
                      90012
------------------------------------------------------------------------
Monetary    Central  1785              $5,000   10/12/2015  Increasing
             Louisi   Jackson                                Timely
             ana      Street                                 Access to
             Aids     Alexand                                HIV Care,
             Suppor   ria, LA                                Testing and
             t        71301                                  Prevention
             Servic                                          Services
             es,
             Inc.
             (CLASS
             )
------------------------------------------------------------------------
Monetary    Coaliti  127 W            $50,000   12/21/2015  Hepatitis C
             on On    127th                                  Education
             Positi   street                                 and
             ve       Suite                                  Services
             Health   208 New                                Project
             Empowe   York,
             rment,   NY
             Inc.     10027
------------------------------------------------------------------------
Monetary    Coastal  400 Mann         $40,000    3/24/2015  Hepatitis
             Bend     Street,                                Education
             AIDS     Suite                                  Program
             Founda   800                                    (HEP)
             tion     Corpus
                      Christi
                      , TX
                      78401
------------------------------------------------------------------------
Monetary    Communi  677 Ala           $7,500    10/3/2015  Integrating
             ty       Moana                                  Hepatitis
             Health   #226                                   Care
             Outrea   Honolul                                Coordinatio
             ch       u, HI                                  n into
             Work     96813                                  Hawaii AIDS
             To                                              Service
             Preven                                          Organizatio
             t Aids                                          ns
------------------------------------------------------------------------
Monetary    Desert   1695 N.           $5,000    3/16/2015  Get Tested
             Aids     Sunrise                                Coachella
             Projec   Way                                    Valley
             t        Palm
                      Springs
                      , CA
                      92262
------------------------------------------------------------------------
Monetary    Exponen  2                 $5,000   11/16/2015  HEPAware
             ts,      Washing                                Project
             Inc.     ton
                      Street,
                      Fourth
                      Floor
                      New
                      York,
                      NY
                      10004
------------------------------------------------------------------------
Monetary    Gay      446 W            $15,000    10/3/2015  HIV
             Men's    33rd St                                Community
             Health   New                                    Education
             Crisis   York,                                  and
                      NY                                     Treatment
                      10001                                  Adherence
                                                             Support
------------------------------------------------------------------------
Monetary    Gay      446 W            $30,000   12/22/2015  Peer
             Men's    33rd St                                Navigation
             Health   New                                    Services
             Crisis   York,                                  for HIV-
                      NY                                     positive
                      10001                                  Transgender
                                                             and Gender
                                                             Non-
                                                             Conforming
                                                             Individuals
------------------------------------------------------------------------
Monetary    Harm     22 West          $30,000     6/5/2015  Hepatitis C
             Reduct   27th                                   and
             ion      Street                                 Injection
             Coalit   5th                                    Drug Use
             ion      Floor                                  Initiative
                      New
                      York,
                      NY
                      10001
------------------------------------------------------------------------
Monetary    Hips     HIPS             $30,000   12/22/2015  Treatment
                      Center                                 Plus: Peer
                      for                                    Based
                      Health                                 Community
                      and                                    Health
                      Achieve                                Worker
                      ment                                   Support to
                      906 H                                  Improve
                      St., NE                                Health
                      Washing                                Outcomes
                      ton, DC                                for Highly
                      20002                                  Marginalize
                                                             d
                                                             Transgender
                                                             Women
------------------------------------------------------------------------
Monetary    Housing  301 West          $7,500    12/8/2015  Hepatitis C
             Works,   37th                                   Peer
             Inc.     Street,                                Navigator
                      #3 New                                 Program
                      York,
                      NY
                      10018
------------------------------------------------------------------------
Monetary    Jackson  P.O. Box          $5,000    8/27/2015  JASMYN
             ville    380103                                 Safety Net
             Area     923                                    Program
             Sexual   Peninsu                                Expansion
             Minori   lar
             ty       Place
             Youth    Jackson
             Networ   ville,
             k,       FL
             Inc.     32205
             (JASMY
             N)
------------------------------------------------------------------------
Monetary    Legacy   4054              $5,000   12/21/2015  Counseling
             Counse   McKinne                                services to
             ling     y                                      individuals
             Center   Avenue,                                living with
                      Suite                                  HIV/AIDS
                      102
                      Dallas,
                      TX
                      75204
------------------------------------------------------------------------
Monetary    Long     2740             $30,000   12/22/2015  Pride for
             Island   Martin                                 Youth POZ
             Crisis   Ave                                    Night
             Center   Bellmor
             , Inc.   e, NY
                      11710
------------------------------------------------------------------------
Monetary    Macedon  1835              $5,000    3/24/2015  Peer
             ia       Centre                                 Navigator
             Family   Avenue,                                for
             And      Suite                                  Prevention/
             Commun   285                                    Case
             ity      Pittsbu                                Management
             Enrich   rgh, PA                                Services
             ment     15219
             Center
------------------------------------------------------------------------
Monetary    Macedon  1835              $5,000   10/23/2015  Peer
             ia       Centre                                 Navigator
             Family   Avenue,                                for
             And      Suite                                  Prevention/
             Commun   285                                    Case
             ity      Pittsbu                                Management
             Enrich   rgh, PA                                Services
             ment     15219                                  Implementat
             Center                                          ion
------------------------------------------------------------------------
Monetary    MCCNY    446 West         $30,000   12/23/2015  Trans in
             Charit   36th                                   Action
             ies      Street
                      New
                      York,
                      NY
                      10018
------------------------------------------------------------------------
Monetary    Mendoci  148              $39,870    3/30/2015  Linkage and
             no       Clara                                  Support
             County   Ave.                                   Services
             AIDS     Ukiah,                                 for PWID's
             Volunt   CA
             eer      95482
             Networ
             k adba
             Mendoc
             ino
             County
             AIDS/
             Viral
             Hepati
             tis
             Networ
             k
------------------------------------------------------------------------
Monetary    Metropo  3251 3rd         $30,000   12/23/2015  TransHealth
             litan    Avenue                                 Care
             Charit   North                                  Coordinatio
             ies,     Suite#1                                n
             Inc.     25 St
                      Petersb
                      urg, FL
                      33713
------------------------------------------------------------------------
Monetary    Minorit  5149 W.           $7,500    4/30/2015  ``G.L.A.M.O.
             y AIDS   Jeffers                                R.''
             Projec   on Blvd                                Getting
             t        Los                                    Linked And
                      Angeles                                Managing
                      , CA                                   Our
                      90016                                  Regimen. It
                                                             is The
                                                             Missing
                                                             Link.
------------------------------------------------------------------------
Monetary    Missour  601              $18,000    3/24/2015  General
             i        Busines                                Charitable
             Hepati   s Loop                                 Contributio
             tis C    70                                     n
             Allian   West,
             ce       Suite
                      134K,
                      Columbi
                      a, MO
                      65203-
                      2585
------------------------------------------------------------------------
Monetary    Montgom  820 W.           $18,000    3/13/2015  Alabama
             ery      Wouth                                  eHealth
             AIDS     Blvd.,                                 Access to
             Outrea   Montgom                                Rural care
             ch       ery, AL                                for HIV/
                      36105                                  AIDS and
                                                             Hepatitis C
------------------------------------------------------------------------
Monetary    Nashvil  633              $18,000   12/22/2015  Brothers
             le       Thompso                                United
             CARES,   n Lane                                 Network of
             Inc.     Nashvil                                Tennessee:
                      le, TN                                 Mobilizatio
                      37204                                  n of Young
                                                             African
                                                             American
                                                             MSM in
                                                             Rural
                                                             Middle and
                                                             East
                                                             Tennessee
------------------------------------------------------------------------
Monetary    Nationa  2140              $5,000    7/15/2015  Brothers
             l AIDS   Martin                                 Like Us
             Educat   Luther                                 (B.L.U.)
             ion      King                                   Project
             and      Jr.
             Servic   Drive
             es for   Atlanta
             Minori   , GA
             ties     30310
------------------------------------------------------------------------
Monetary    Nationa  2140             $30,000   12/22/2015  Be Connected
             l AIDS   Martin                                 Mentoring
             Educat   Luther                                 Program
             ion      King
             and      Jr.
             Servic   Drive
             es for   Atlanta
             Minori   , GA
             ties     30310
------------------------------------------------------------------------
Monetary    Nationa  580             $200,000    2/25/2015  Hepatitis C
             l AIDS   Broadwa                                Project,
             Treatm   y Suite                                HIV Too
             ent      1010
             Advoca   New
             cy       York,
             Projec   NY
             t        10012
------------------------------------------------------------------------
Monetary    Nationa  National        $150,000   11/17/2015  Affordable
             l        Latino                                 Care Act
             Allian   AIDS                                   (ACA),
             ce of    Action                                 Viral
             State    Network                                Hepatitis,
             and      and                                    and Ryan
             Territ   Nationa                                White/ADAP
             orial    l                                      Public
             AIDS     Allianc                                Policy and
             Direct   e of                                   Technical
             ors      State                                  Assistance
                      and                                    Programs
                      Territo
                      rial
                      AIDS
                      Directo
                      rs 444
                      N
                      Capitol
                      St
                      Suite
                      339
                      Washing
                      ton, DC
                      20001
------------------------------------------------------------------------
Monetary    Nationa  Post              $7,500    7/27/2015  Black LGBT
             l        Office                                 Health and
             Black    Box                                    Wellness
             Justic   71395                                  Initiative
             e        Washing
             Coalit   ton, DC
             ion,     20024
             Inc.
------------------------------------------------------------------------
Monetary    Nationa  1825             $35,000    3/10/2015  Strong
             l        Connect                                Communities
             Minori   icut                                   :
             ty       Avenue,                                Strengtheni
             AIDS     NW                                     ng
             Counci   Washing                                connections
             l        ton, DC                                between
                      20009-                                 communities
                      5721                                   of color
                                                             and the
                                                             healthcare
                                                             providers
                                                             that serve
                                                             them.
------------------------------------------------------------------------
Monetary    New      44 South          $5,000    8/27/2015  Support of
             Jersey   Street                                 case
             AIDS     Morrist                                management
             Servic   own, NJ
             es       07960
------------------------------------------------------------------------
Monetary    Next     99                $5,000    7/27/2015  Next Step
             Step     Bishop                                 Transitiona
             Fund,    Allen                                  l Support
             Inc.     Drive                                  for HIV+
                      Cambrid                                Teens and
                      ge, MA                                 Young
                      02139                                  Adults
------------------------------------------------------------------------
Monetary    Our      2727 SE           $5,000    3/13/2015  NHCP:
             House    Alder                                  Independent
             Of       St.                                    Living
             Portla   Portlan                                Support for
             nd       d, OR                                  Individuals
             Incorp   97214                                  with HIV/
             orated                                          AIDS
------------------------------------------------------------------------
Monetary    Philade  1233             $10,000    6/25/2015  End AIDS
             lphia    Locust                                 Summit/AIDS
             Fight    St.                                    Education
                      Philade                                Month 2015
                      lphia,
                      PA
                      19107
------------------------------------------------------------------------
Monetary    Project  273              $40,000    3/13/2015  The Support
             Inform   Ninth                                  Partnership
                      Street
                      San
                      Francis
                      co, CA
                      94103
------------------------------------------------------------------------
Monetary    Project  273              $65,000    6/12/2015  Mission
             Inform   Ninth                                  Support for
                      Street                                 Project
                      San                                    Inform
                      Francis
                      co, CA
                      94103
------------------------------------------------------------------------
Monetary    Project  P.O. Box          $5,000    10/3/2015  Transitional
             Transi   4826                                   Supportive
             tions,   Austin,                                Housing
             Inc.     TX                                     Programs
                      78765
------------------------------------------------------------------------
Monetary    Resourc  2701              $3,000    5/27/2015  Valor
             e        Reagan                                 Latino--HIV
             Center   Street                                 Prevention
             of       Dallas,                                Program
             Dallas   TX
             , Inc.   75219
------------------------------------------------------------------------
Monetary    San      2508             $20,000     8/3/2015  Creating
             Diego    Histori                                Circles of
             Human    c                                      Care
             Dignit   Decatur
             y        Road
             Founda   Suite
             tion     160 San
                      Diego,
                      CA
                      92106
------------------------------------------------------------------------
Monetary    Set      8035 E.           $5,000    10/3/2015  Phenomenal
             Apart    R.L.                                   Woman
             Aiming   Thornto                                Program
             Victor   n Frwy.                                (PWP)
             iously   Suite
             To       424
             Elimat   Dallas,
             e        TX
             Diseas   75228
             es
------------------------------------------------------------------------
Monetary    Sexual   410 7th          $30,000   12/22/2015  Peer
             Minori   st SE                                  Education:
             ty       Washing                                Empowering
             Youth    ton, DC                                young MSM
             Assist   20003                                  of color to
             ance                                            end HIV.
             League
             (SMYAL
             ) DBA:
             Suppor
             ting
             and
             Mentor
             ing
             Youth
             Advoca
             tes
             and
             Leader
             s
------------------------------------------------------------------------
Monetary    Shanti   730 Polk         $15,000    7/14/2015  Shanti's Hep
             Projec   Street                                 C Pilot
             t,       3rd                                    Expansion
             Inc.     Floor                                  of our HIV
                      San                                    Services
                      Francis                                Program
                      co, CA
                      94109
------------------------------------------------------------------------
Monetary    Someone  1950             $30,000   12/22/2015  Improving
             Cares    Spectru                                Linkage to
             Inc Of   m                                      Care and
             Atlant   Circle                                 Retention
             a        Ste.                                   among
                      A145                                   Transgender
                      Mariett                                Women and
                      a, GA                                  Gender
                      30067                                  Nonconformi
                                                             ng People
                                                             Living with
                                                             HIV Project
                                                             title:
                                                             Transformin
                                                             g, Renewing
                                                             and
                                                             Unifying
                                                             Transgender
                                                             Health
                                                             Project
                                                             (TRUTH)
------------------------------------------------------------------------
Monetary    Southwe  300               $5,000     9/3/2015  HIV Care in
             st       Southwe                                a Safety
             Boulev   st                                     Net Clinic
             ard      Bouleva                                Setting
             Family   rd
             Health   Kansas
             Care,    City,
             Inc.     KS
                      66103
------------------------------------------------------------------------
Monetary    Southwe  1101 N.           $4,500    5/15/2015  Hepatitis C
             st       Central                                Education
             Center   Avenue,                                and Support
             For      Suite                                  for High-
             HIV/     200                                    risk
             AIDS,    phoenix                                Populations
             Inc.     , AZ
                      85004
------------------------------------------------------------------------
Monetary    St       808 W.           $40,000    3/10/2015  South L.A.
             Johns    58th                                   Mobile
             Well     Street                                 Health--Pee
             Child    Los                                    r Navigator
             And      Angeles                                Program for
             Family   , CA                                   PWID Living
             Center   90037                                  with HIV
             , Inc.                                          and/or
                                                             Hepatitis C
------------------------------------------------------------------------
Monetary    St.      1111             $75,000   12/22/2015  FINISH THE
             Luke's   Amsterd                                JOB:
             Roosev   am Ave                                 Providing
             elt      New                                    HCV care to
             Hospit   York,                                  current or
             al       NY                                     former IV
             Center   10025                                  drug users
                                                             previously
                                                             diagnosed
                                                             through
                                                             governmenta
                                                             l testing
                                                             programs.
------------------------------------------------------------------------
Monetary    The      17 Davis         $65,000    7/14/2015  Ensuring
             AIDS     Blvd.                                  Adequate
             Instit   Suite                                  Funding for
             ute      403                                    Domestic
                      Tampa,                                 HIV/AIDS
                      FL                                     and
                      33606                                  Hepatitis
                                                             Programs
------------------------------------------------------------------------
Monetary    The Hep  1325 S.          $25,000    5/20/2015  Hepatitis C
             C        Colorad                                Testing and
             Connec   o                                      Linkage to
             tion     Blvd.,                                 Care
                      B-302
                      Denver,
                      CO
                      80222
------------------------------------------------------------------------
Monetary    The      PO Box           $39,000    3/13/2015  The Open
             Open     99243                                  Door: Peer
             Door,    Pittsbu                                Support for
             Inc.     rgh, PA                                HIV
                      15233                                  Engagement
                                                             and
                                                             Retention
                                                             in Care
------------------------------------------------------------------------
Monetary    The      85               $15,000    5/15/2015  Women's HIV
             Well     Norman                                 Treatment
             Projec   Avenue,                                Advocacy
             t        Suite 1                                Development
                      Brookly                                Program
                      n, NY
                      11222
------------------------------------------------------------------------
Monetary    The      85               $15,000    7/21/2015  Charitable
             Well     Norman                                 Donation
             Projec   Avenue,                                for Online
             t        Suite 1                                Resources
                      Brookly                                and Program
                      n, NY                                  Evaluation/
                      11222                                  Outcome
                                                             Measurement
------------------------------------------------------------------------
Monetary    The      8101              $5,000    7/15/2015  Personal
             Wright   Cameron                                Disease
             House    Rd.,                                   Management
             Wellne   Suite                                  for HIV/
             ss       105                                    AIDS and
             Center   Austin,                                HepC
             , Inc.   TX                                     Clients
                      78754
------------------------------------------------------------------------
Monetary    TPA      5050 N.          $20,000    10/8/2015  Peer Health
             Networ   Broadwa                                Navigation
             k        y Suite                                Services
             Incorp   300
             orated   Chicago
             Test     , IL
             Positi   60640
             ve
             Aware
             Networ
             k
------------------------------------------------------------------------
Monetary    TPA      5050 N.          $26,056   12/22/2015  Youth
             Networ   Broadwa                                Investment
             k        y Suite
             Incorp   300
             orated   Chicago
             Test     , IL
             Positi   60640
             ve
             Aware
             Networ
             k
------------------------------------------------------------------------
Monetary    Treatme  261              $40,000    5/21/2015  Case Studies
             nt       Fifth
             Action   Ave
             Group,   Suite
             Inc.     2110
                      New
                      York,
                      NY
                      10016
------------------------------------------------------------------------
Monetary    Univers  UCSF              $7,500    8/27/2015  Mission-
             ity of   Allianc                                Based
             Califo   e                                      Support of
             rnia     Health                                 UCSF
             San      Project                                Alliance
             Franci   1855                                   Health
             sco      Folsom                                 Project
                      Street,                                Services
                      Ste.                                   for People
                      670 Box                                Living With
                      0884                                   or at Risk
                      San                                    of HIV/AIDS
                      Francis
                      co, CA
                      94143
------------------------------------------------------------------------
Monetary    Univers  51                $7,500   10/23/2015  The
             ity of   Goodman                                Cincinnati
             Cincin   Drive                                  Exchange
             nati     Suite                                  Project: A
                      100,                                   Public
                      P.O.                                   Health
                      Box                                    Initiative
                      19970
                      Cincinn
                      ati, OH
                      45219-
                      0970
------------------------------------------------------------------------
Monetary    US       1300 PA       $1,000,000   10/23/2015  Sirturo
             Agency   Avenue.                                Donation
             for      , NW,                                  Program--US
             Intern   SA-44                                  AID
             ationa   Rm 475-                                Agreement
             l        J
             Develo   Washing
             pment    ton, DC
                      20523
------------------------------------------------------------------------
Monetary    Vermont  P. O.            $40,000    3/10/2015  Expansion of
             Commit   Box                                    Vermont's
             tee      5248                                   Services to
             For      Burling                                Improve
             Aids     ton, VT                                Care for
             Resour   05402                                  PWID Living
             ces                                             with HCV
             Educat
             ion
             and
             Servic
             es
------------------------------------------------------------------------
Monetary    Warren-  511 Ruin         $28,800   12/22/2015  Online
             Vance    Creek                                  Linkage and
             Commun   Rd STE                                 Retention
             ity      105                                    Project for
             Health   Henders                                YMSM
             Center   on, NC
             , Inc.   27536
------------------------------------------------------------------------
Monetary    Washing  566 West         $40,000    3/13/2015  Engaging
             ton      181st                                  High Risk
             Height   Street,                                Active
             s        Floor 2                                Injection
             CORNER   New                                    Drug Users
             Projec   York,                                  in
             t        NY                                     Hepatitis C
                      10033                                  testing and
                                                             Treatment
                                                             in Northern
                                                             Manhattan
------------------------------------------------------------------------
Monetary    Wellnes  2921 NE           $5,000    7/15/2015  Sister-to-
             s        6th Ave                                Sister
             Center   Wilton
             of       Manors,
             South    FL
             Florid   33334
             a,
             Inc.
------------------------------------------------------------------------
Monetary    WORLD    449 15th         $15,000   12/17/2015  2nd CHANCE
             Women    St.,                                   (Creating a
             Organi   Suite                                  Healthy and
             zed to   303                                    Nurturing
             Respon   Oakland                                Community
             d to     , CA                                   Environment
             Life-    94612                                  )
             threat
             ening
             Diseas
             es
------------------------------------------------------------------------
Product     Johnson  One          $13,174,000    3/15/2013  Patient
             &        Johnson                                Assistance
             Johnso   &                                      Product
             n        Johnson                                Donation
             Patien   Plaza,
             t        New
             Assist   Brunswi
             ance     ck, NJ
             Founda   08933
             tion
------------------------------------------------------------------------
Product     Johnson  One           $6,019,000    6/15/2013  Patient
             &        Johnson                                Assistance
             Johnso   &                                      Product
             n        Johnson                                Donation
             Patien   Plaza,
             t        New
             Assist   Brunswi
             ance     ck, NJ
             Founda   08933
             tion
------------------------------------------------------------------------
Product     Johnson  One          $59,199,000    9/15/2013  Patient
             &        Johnson                                Assistance
             Johnso   &                                      Product
             n        Johnson                                Donation
             Patien   Plaza,
             t        New
             Assist   Brunswi
             ance     ck, NJ
             Founda   08933
             tion
------------------------------------------------------------------------
Product     Johnson  One           $4,718,000   12/15/2013  Patient
             &        Johnson                                Assistance
             Johnso   &                                      Product
             n        Johnson                                Donation
             Patien   Plaza,
             t        New
             Assist   Brunswi
             ance     ck, NJ
             Founda   08933
             tion
------------------------------------------------------------------------
Updated March 24, 2016


  Janssen Biotech, Inc. Monetary and Product Contribution to U.S.-based
                 Charitable Organizations Full Year 2016
        (Payments made from January 1, 2016 to December 31, 2016)
------------------------------------------------------------------------
                                                               Project
 Donation    Payee     Payee   Payment Amount    Payment       Title/
   Type              Address        (USD)          Date      Description
------------------------------------------------------------------------
Monetary    Aid For  12271               $300    9/19/2016  Costs
             Friend   Townsen                                associated
             s        d Rd                                   with 2016
                      Philade                                Janssen
                      lphia,                                 Cares
                      PA                                     Volunteer
                      19154                                  Activity
------------------------------------------------------------------------
Monetary    America  2310              $1,500    4/11/2016  2016 Run for
             n        Route                                  Dad,
             Cancer   34,                                    Awareness
             Societ   Suite                                  Sponsor
             y Inc.   1D
                      Manasqu
                      an, NJ
                      08736
------------------------------------------------------------------------
Monetary    America  1626              $1,000    4/15/2016  Relay For
             n        Locust                                 Life of the
             Cancer   Street                                 Wissahickon
             Societ   Philade                                Valley
             y Inc.   lphia,
                      PA
                      19103
------------------------------------------------------------------------
Monetary    Arthrit  1355            $200,000     6/3/2016  Renewal
             is       Peachtr                                support of
             Founda   ee                                     Arthritis
             tion     Street,                                Foundation
                      Suite                                  Run / Walk
                      600                                    series -
                      Atlanta                                Walk to
                      , GA                                   Cure
                      30309                                  Arthritis
                                                             and Jingle
                                                             Bell Run
------------------------------------------------------------------------
Monetary    Arthrit  1355            $100,000    4/11/2016  General
             is       Peachtr                                Operating
             Founda   ee                                     Support
             tion     Street,
                      Suite
                      600
                      Atlanta
                      , GA
                      30309
------------------------------------------------------------------------
Monetary    Arthrit  2280                 $75     3/7/2016  Employee
             is       South                                  directed
             Founda   Albion                                 donation in
             tion,    Street                                 lieu of
             Great    Denver,                                company
             West     CO                                     holiday
             Region   80222-                                 gift
             , Inc.   4906
------------------------------------------------------------------------
Monetary    Bicol    21019             $1,425     3/8/2016  Employee
             Founda   47th                                   directed
             tion     Ave W                                  donation in
                      Lynnwoo                                lieu of
                      d, WA                                  company
                      98036                                  holiday
                                                             gift
------------------------------------------------------------------------
Monetary    Cancer   200 Kirk          $2,000    8/17/2016  Paws 4 Life
             Suppor   Road PO                                Dog Walk
             t        Box
             Commun   3187
             ity of   Warmins
             Philad   ter, PA
             elphia   18974
------------------------------------------------------------------------
Monetary    Cancer   200 Kirk          $2,500    8/30/2016  Celebration
             Suppor   Road PO                                of Hope
             t        Box
             Commun   3187
             ity of   Warmins
             Philad   ter, PA
             elphia   18974
------------------------------------------------------------------------
Monetary    Cancer   200 Kirk            $900    9/13/2016  Costs
             Suppor   Road PO                                associated
             t        Box                                    with 2016
             Commun   3187                                   Janssen
             ity of   Warmins                                Cares
             Philad   ter, PA                                Volunteer
             elphia   18974                                  Activity
------------------------------------------------------------------------
Monetary    Cancer   944               $3,500     8/5/2016  Cancer
             Suppor   Marcon                                 Support and
             t        Blvd.,                                 Education
             Commun   #110                                   Allentown,
             ity of   Allento                                PA
             the      wn, PA
             Greate   18109
             r
             Lehigh
             Valley
------------------------------------------------------------------------
Monetary    Canine   PO Box              $300    9/14/2016  Costs
             Partne   170                                    associated
             rs for   Cochran                                with 2016
             Life     ville,                                 Janssen
                      PA                                     Cares
                      19330                                  Volunteer
                                                             Activity
------------------------------------------------------------------------
Monetary    Center   1900              $5,000    5/27/2016  Project for
             for      Cherry                                 Medically
             Child    Street                                 Needy
             Advoca   Philade                                Children
             tes      lphia,
                      PA
                      19103
------------------------------------------------------------------------
Monetary    Childre  CHOP              $5,000    4/12/2016  7th Annual
             n's      Foundat                                Walk for
             Hospit   ion                                    Hope
             al of    ATTN:                                  benefiting
             Philad   Holly                                  pediatric
             elphia   Hubbard/                               Inflammator
             Founda   Walk                                   y Bowel
             tion     for                                    Disease
                      Hope                                   Research
                      2016 PO
                      Box
                      40930
                      34th
                      and
                      Civic
                      Center
                      Blvd.
                      Philade
                      lphia,
                      NJ
                      19107
------------------------------------------------------------------------
Monetary    Communi  300B             $20,000   12/14/2016  Free medical
             ty       Lawrenc                                and dental
             Volunt   e Drive                                care
             eers     West                                   services
             in       Chester                                for
             Medici   , PA                                   uninsured
             ne       19380                                  families in
                                                             Chester
                                                             County
------------------------------------------------------------------------
Monetary    Crohn's  733             $135,000    2/26/2016  Take Steps
             and      Third                                  2016 Walk
             Coliti   Avenue                                 Program
             s        Suite
             Founda   510 New
             tion     York,
             of       NY
             Americ   10017
             a,
             Inc.
------------------------------------------------------------------------
Monetary    Crohn's  733               $5,000    6/13/2016  Disease
             and      Third                                  State
             Coliti   Ave,                                   Awareness
             s        Suite                                  (DSA) Word
             Founda   510 New                                Cloud
             tion     York,                                  Activity
             of       NY
             Americ   10017
             a,
             Inc.
------------------------------------------------------------------------
Monetary    Crohn's  733              $18,000    6/13/2016  Camp Oasis
             and      Third
             Coliti   Ave,
             s        Suite
             Founda   510 New
             tion     York,
             of       NY
             Americ   10017
             a,
             Inc.-
             NY
             Chapte
             r
------------------------------------------------------------------------
Monetary    Delawar  236               $5,000    3/21/2016  Teacher
             e        Randell                                Development
             Valley   Hall                                   Program
             Scienc   3141
             e        Chestnu
             Fairs,   t
             Inc.     Street
                      Philade
                      lphia,
                      PA
                      19104
------------------------------------------------------------------------
Monetary    Doernbe  1121 SW              $75    3/21/2016  Employee
             cher     Salmon                                 directed
             Childr   St #100                                donation in
             en's     Portlan                                lieu of
             Hospit   d, OR                                  company
             al       97205                                  holiday
             Founda                                          gift
             tion
------------------------------------------------------------------------
Monetary    Family   142              $25,000    9/30/2016  Family Reach
             Reach    Berkele                                Foundation
             Founda   y                                      General
             tion     Street,                                Support
                      4th
                      Floor
                      Boston,
                      MA
                      02116
------------------------------------------------------------------------
Monetary    Family   142             $250,000   12/22/2016  Family Reach
             Reach    Berkele                                Programmati
             Founda   y                                      c Support
             tion     Street;
                      4th
                      Floor
                      Boston,
                      MA
                      02116
------------------------------------------------------------------------
Monetary    Food     1501              $5,000   12/15/2016  Year Round
             Bank     John                                   Youth
             of       Tipton                                 Feeding
             South    Blvd                                   Programs
             Jersey   Pennsau
                      ken
                      Townshi
                      p, NJ
                      08110
------------------------------------------------------------------------
Monetary    Friends  113 West          $3,000   12/26/2016  Outreach to
             Associ   Chestnu                                Homeless
             ation    t                                      Families
             For      Street
             Care     West
             and      Chester
             Protec   , PA
             tion     19380
             Of
             Childr
             en
------------------------------------------------------------------------
Monetary    Georgia  560               $1,700    4/12/2016  Free
             Prosta   Barnesl                                Prostate
             te       ey Lane                                Cancer
             Cancer   Alphare                                Screening
             Coalit   tta, GA
             ion      30022
             Inc.
------------------------------------------------------------------------
Monetary    Girl     330               $4,000   10/10/2016  Girl Scouts
             Scouts   Manor                                  of Eastern
             of       Road                                   Pennsylvani
             Southe   Miquon,                                a Science,
             astern   PA                                     Technology,
             Pennsy   19444                                  Engineering
             lvania                                          , and Math
                                                             (STEM)
                                                             programming
                                                             .
------------------------------------------------------------------------
Monetary    Green    1368             $15,000   12/15/2016  Watershed
             Valley   Prizer                                 Science
             s        Road                                   Education
             Associ   Pottsto                                Program
             ation    wn, PA
                      19465
------------------------------------------------------------------------
Monetary    Habitat  1847 E            $2,000    5/30/2016  Building
             for      Lincoln                                communities
             Humani   Hwy                                    and
             ty of    Coatesv                                changing
             Cheste   ille,                                  lives
             r        PA
             County   19320
             , Inc.
------------------------------------------------------------------------
Monetary    Habitat  1829 N.             $300    11/3/2016  Costs
             For      19th                                   associated
             Humani   Street                                 with 2016
             ty       Philade                                Janssen
             Philad   lphia,                                 Cares
             elphia   PA                                     Volunteer
             Inc.     19121                                  Activity
------------------------------------------------------------------------
Monetary    Habitat  1829 N.           $5,000   12/26/2016  Diamond Park
             For      19th                                   Phase 2--
             Humani   Street                                 affordable
             ty       Philade                                housing
             Philad   lphia,
             elphia   PA
             Inc.     19121
------------------------------------------------------------------------
Monetary    Hatboro- 229              $25,000   12/14/2016  STEM
             Horsha   Meeting                                Programs
             m        house                                  for Hatboro-
             Educat   Road                                   Horsham
             ional    Horsham                                Students
             Founda   , PA
             tion     19044
------------------------------------------------------------------------
Monetary    Horsham  PO Box            $1,000     8/5/2016  K9 Program
             Neighb   621                                    Fit Out and
             ors      Horsham                                National
             Associ   , PA                                   Night Out
             ation    19044                                  Celebration
------------------------------------------------------------------------
Monetary    Junior   994 Old           $7,500    8/18/2016  Junior
             Achiev   Eagle                                  Achievement
             ement    School                                 Whole
             Of       Rd                                     School
             Delawa   Suite                                  Initiative
             re       1014
             Valley   Wayne,
                      PA
                      19087
------------------------------------------------------------------------
Monetary    Kids     26071             $3,000    8/30/2016  Support
             Connec   Merit                                  Groups for
             ted      Circle,                                the
                      #103                                   Children of
                      Laguna                                 Cancer
                      Hills,                                 Patients
                      CA
                      92653-
                      7016
------------------------------------------------------------------------
Monetary    Melanom  250                 $100    9/30/2016  Memorial
             a        Maplefl                                Donation
             Intern   ower
             ationa   Road
             l        Glenmoo
             Founda   re, PA
             tion     19343
------------------------------------------------------------------------
Monetary    Metropo  2323             $25,000   12/16/2016  Medically
             litan    Ranstea                                Appropriate
             Area     d                                      Meals for
             Neighb   Street                                 People with
             orhood   Philade                                Critical
             Nutrit   lphia,                                 Illnesses
             ion      PA
             Allian   19103
             ce
             (MANNA
             )
------------------------------------------------------------------------
Monetary    Mitzvah  1561                $300    9/22/2016  Costs
             Circle   Gehman                                 associated
             Founda   Road                                   with 2016
             tion     Harleys                                Janssen
                      ville,                                 Cares
                      PA                                     Volunteer
                      19438                                  Activity
------------------------------------------------------------------------
Monetary    Mitzvah  1561              $5,000     8/5/2016  Critical
             Circle   Gehman                                 Needs
             Founda   Road                                   Support for
             tion     Harleys                                Individuals
                      ville,                                 and
                      PA                                     Families
                      19438
------------------------------------------------------------------------
Monetary    Montgom  340              $10,000    12/9/2016  The Study of
             ery      DeKalb                                 Psychology
             County   Pike                                   as a Guide
             Commun   Blue                                   to Peer
             ity      Bell,                                  Mentorship
             Colleg   PA                                     for BTE--
             e        19422                                  Wissahickon
             Founda
             tion
------------------------------------------------------------------------
Monetary    Montgom  340              $23,811    12/9/2016  Bridge to
             ery      DeKalb                                 Employment-
             County   Pike                                   -Wissahicko
             Commun   Blue                                   n
             ity      Bell,
             Colleg   PA
             e        19422
             Founda
             tion
------------------------------------------------------------------------
Monetary    Mt.      One              $50,000   10/18/2016  Overcoming
             Sinai    Gustave                                the
             Medica   L. Levy                                Barriers to
             l        Place                                  Clinical
             Center   Box                                    Care for
                      1049                                   Underserved
                      New                                    Multiple
                      York,                                  Myeloma
                      NY                                     Patients
                      10029
------------------------------------------------------------------------
Monetary    Multipl  383 Main         $50,000   12/22/2016  MMRF
             e        Avenue                                 Endurance
             Myelom   5th                                    Events
             a        Floor
             Resear   Norwalk
             ch       , CT
             Founda   06851
             tion
------------------------------------------------------------------------
Monetary    Multipl  383 Main        $100,000   12/22/2016  2017 MMRF
             e        Avenue                                 Team for
             Myelom   5th                                    Cures 5K
             a        Floor                                  Walk/Run
             Resear   Norwalk                                Program
             ch       , CT
             Founda   06851
             tion
------------------------------------------------------------------------
Monetary    Multipl  383 Main        $275,000   12/22/2016  MMy Ride for
             e        Avenue                                 a Cure
             Myelom   5th
             a        Floor
             Resear   Norwalk
             ch       , CT
             Founda   06851
             tion
------------------------------------------------------------------------
Monetary    Multipl  383 Main         $40,000   12/23/2016  MMRF Patient
             e        Avenue                                 Support
             Myelom   5th                                    Center
             a        Floor
             Resear   Norwalk
             ch       , CT
             Founda   06851
             tion
------------------------------------------------------------------------
Monetary    Multipl  51 Locus        $100,000    2/23/2016  2016 MMRF
             e        Avenue                                 Team for
             Myelom   Suite                                  Cures 5K
             a        201                                    Walk/Run
             Resear   Norwalk                                Program
             ch       , CT
             Founda   06851
             tion
------------------------------------------------------------------------
Monetary    Multipl  383 Main         $50,000     3/7/2016  2016 MMRF
             e        Avenue                                 Team for
             Myelom   5th                                    Cures
             a        Floor                                  Endurance
             Resear   Norwalk                                Events
             ch       , CT                                   Program
             Founda   06851
             tion
------------------------------------------------------------------------
Monetary    Nationa  4950              $2,500    4/15/2016  Run/Walk to
             l        York                                   Break the
             Ovaria   Rd,                                    Silence on
             n        Unit                                   Ovarian
             Cancer   631                                    Cancer
             Coalit   Holicon
             ion      g, PA
             Inc.     18928
------------------------------------------------------------------------
Monetary    Nationa  6600 SW          $50,000     5/3/2016  2016 Team
             l        92nd                                   NPF Walk
             Psoria   Ave.,
             sis      #300
             Founda   Portlan
             tion     d, OR
                      97223
------------------------------------------------------------------------
Monetary    NET      499 N.            $1,125     3/4/2016  Employee
             Treatm   5th                                    directed
             ent      St.,                                   donation in
             Servic   Suite A                                lieu of
             es       Philade                                company
                      lphia,                                 holiday
                      PA                                     gift
                      19123
------------------------------------------------------------------------
Monetary    Philade  1729             $75,000   12/27/2016  STEAM Mural
             lphia    Mount                                  Initiative
             Mural    Vernon
             Arts     Street
             Progra   Philade
             m        lphia,
                      PA
                      19130
------------------------------------------------------------------------
Monetary    Project  1515              $1,000   12/16/2016  Mental
             HOME     Fairmou                                Health and
                      nt                                     Recovery
                      Avenue                                 Services
                      Philade
                      lphia,
                      PA
                      19130
------------------------------------------------------------------------
Monetary    Prostat  7009 S.          $30,000    5/20/2016  Prostate
             e        Potomac                                Cancer
             Cancer   Street                                 Disparities
             Educat   Suite                                  Outreach
             ion      125                                    Program
             Counci   Centenn
             l        ial, CO
                      80112
------------------------------------------------------------------------
Monetary    Prostat  500              $50,000     2/8/2016  Partnerships
             e        Victory                                for
             Health   Road                                   Education,
             Educat   Quincy,                                Support and
             ion      MA                                     Outreach
             Networ   02170
             k Inc.
------------------------------------------------------------------------
Monetary    Reach    89 South          $5,000   12/21/2016  Preparing
             Out      Street,                                Families
             and      Suite                                  for School
             Read     201                                    Success
                      Boston,
                      MA
                      02111
------------------------------------------------------------------------
Monetary    Rebuild  4355              $5,000    4/12/2016  Mantua Block
             ing      Orchard                                Build 2016
             Togeth   Street
             er       Suite
             Philad   2R
             elphia   Philade
                      lphia,
                      PA
                      19124
------------------------------------------------------------------------
Monetary    Regiona  30                  $100    6/10/2016  Memorial
             l        Milesto                                Donation
             Hospic   ne Road
             e and    Danbury
             Home     , CT
             Care     06810
             Center
------------------------------------------------------------------------
Monetary    Retired  901 East          $7,000    5/23/2016  RSVP's
             and      8th                                    America
             Senior   Street                                 Reads/
             Volunt   Suite                                  Writes and
             eer      200                                    Protege One-
             Progra   King of                                on-One
             m of     Prussia                                Mentoring
             Montgo   , PA                                   Programs.
             mery     19406
             County
------------------------------------------------------------------------
Monetary    Retired  901 East         $10,000   12/15/2016  RSVP's
             and      8th                                    Family
             Senior   Street                                 Literacy
             Volunt   Suite                                  Volunteer
             eer      200                                    Program
             Progra   King of                                (FLVP) and
             m of     Prussia                                My Free
             Montgo   , PA                                   Tutor (MFT)
             mery     19406                                  virtual
             County                                          STEM
                                                             tutoring
                                                             and career
                                                             awareness
                                                             Program.
------------------------------------------------------------------------
Monetary    Riverbe  1950              $6,000     8/5/2016  Outreach to
             nd       Spring                                 Children/
             Enviro   Mill                                   Access to
             nmenta   Road                                   Nature/
             l        Gladwyn                                Norristown
             Educat   e, PA                                  Area School
             ion      19035                                  District
             Center
------------------------------------------------------------------------
Monetary    Sandy    2010              $2,000   12/14/2016  Sandy Sprint
             Rollma   West                                   Superhero
             n        Chester                                5K or 10K
             Ovaria   Pike,                                  Run/Walk
             n        Suite
             Cancer   410
             Founda   Haverto
             tion,    wn, PA
             Inc.     19083
------------------------------------------------------------------------
Monetary    SARC     24 Frank          $9,500    9/22/2016  General
                      Lloyd                                  Operating
                      Wright                                 Support--We
                      Drive A/                               bsite
                      3100 PO
                      Box 406
                      Ann
                      Arbor,
                      MI
                      48105
------------------------------------------------------------------------
Monetary    Special  2800                $300    9/22/2016  Costs
             Equest   Street                                 associated
             rians    Road                                   with 2016
                      P.O.                                   Janssen
                      Box                                    Cares
                      1001                                   Volunteer
                      Warring                                Activity
                      ton, PA
                      18976
------------------------------------------------------------------------
Monetary    Special  2800              $4,000   10/10/2016  Special
             Equest   Street                                 Equestrians
             rians    Road                                   Equine-
                      P.O.                                   Assisted
                      Box                                    Learning
                      1001                                   and
                      Warring                                Therapeutic
                      ton, PA                                Riding
                      18976                                  Program
------------------------------------------------------------------------
Monetary    Starfin  4015             $10,000    4/19/2016  Starfinder's
             der      Main                                   Soccer,
             Founda   Street                                 Education,
             tion     Philade                                and
                      lphia,                                 Leadership
                      PA                                     Development
                      19127                                  Programs
                                                             for Youth
------------------------------------------------------------------------
Monetary    The      The              $12,000    4/19/2016  Family Care
             Childr   Childre                                Binder
             en's     n's                                    Program
             Hospit   Hospita
             al of    l of
             Philad   Philade
             elphia   lphia
             Founda   Foundat
             tion     ion
                      Attn:
                      Staci
                      Carney,
                      Associa
                      te
                      Directo
                      r,
                      Corpora
                      te and
                      Foundat
                      ion
                      Relatio
                      ns 100
                      Penn
                      Square
                      East
                      8th
                      Floor,
                      Suite
                      8050
                      Philade
                      lphia,
                      PA
                      19107
------------------------------------------------------------------------
Monetary    The      The               $5,000    4/12/2016  Child Life,
             Childr   Childre                                Education,
             en's     n's                                    and
             Hospit   Hospita                                Creative
             al of    l of                                   Arts
             Philad   Philade                                Therapy
             elphia   lphia                                  Program
             Founda   Foundat
             tion     ion
                      Attn:
                      Staci
                      Carney,
                      Associa
                      te
                      Directo
                      r,
                      Corpora
                      te and
                      Foundat
                      ion
                      Relatio
                      ns 100
                      Penn
                      Square
                      East
                      8th
                      Floor,
                      Suite
                      8050
                      Philade
                      lphia,
                      PA
                      19107
------------------------------------------------------------------------
Monetary    The      222              $10,000   12/26/2016  Corporate
             Frankl   North                                  Membership
             in       20th
             Instit   St.
             ute      Philade
                      lphia,
                      PA
                      19103
------------------------------------------------------------------------
Monetary    The      622               $2,000    8/18/2016  General
             Giving   Evans                                  Operating
             Tree     Road PO                                Support
                      Box 823                                with an
                      Gwynedd                                emphasis on
                      Valley,                                the Public
                      PA                                     Educational
                      19437                                  Giving
                                                             Events
------------------------------------------------------------------------
Monetary    The      2600             $10,000    3/24/2016  Hubert J.P.
             Melmar   Wayland                                Schoemaker
             k        Road                                   Classic
             Charit   Berwyn,
             able     PA
             Founda   19312
             tion
------------------------------------------------------------------------
Monetary    The      400                 $600    9/19/2016  Costs
             Pennsb   Pennsbu                                associated
             ury      ry                                     with 2016
             Societ   Memoria                                Janssen
             y        l Road                                 Cares
                      Morrisv                                Volunteer
                      ille,                                  Activity
                      PA
                      19067
------------------------------------------------------------------------
Monetary    The      775 E             $9,500     8/5/2016  Sarcoma
             Sarcom   Blithed                                Alliance
             a        ale                                    General
             Allian   #334                                   Support
             ce       Mill
                      Valley,
                      CA
                      94941
------------------------------------------------------------------------
Monetary    Trustee  3025              $5,000   12/26/2016  WXPN
             s Of     Walnut                                 Musicians
             The      Street                                 On Call
             Univer   Philade
             sity     lphia,
             Of       PA
             Pennsy   19104
             lvania
------------------------------------------------------------------------
Monetary    Turning  415               $5,000    4/12/2016  Families and
             Points   South                                  Schools
             For      15th                                   Together
             Childr   Street                                 (FAST)
             en       Philade                                Program
                      lphia,
                      PA
                      19146
------------------------------------------------------------------------
Monetary    United   1709            $245,879   12/19/2016  Impact Fund
             Way of   Benjami                                Greater
             Southe   n                                      Philadelphi
             astern   Frankli                                a, PA and
             Pennsy   n                                      Southern,
             lvania   Parkway                                NJ
                      Philade
                      lphia,
                      PA
                      19103
------------------------------------------------------------------------
Monetary    Youth    949               $5,000    12/9/2016  The Youth
             Rally    Chestnu                                Rally--a
             Commit   t Oak                                  camp for
             tee      Dr St.                                 kids/teens
             Inc.     Charles                                living with
                      , MO                                   conditions
                      63303                                  affecting
                                                             the bowel
                                                             (Crohn's
                                                             Disease and
                                                             UC) and
                                                             bladder
                                                             systems.
------------------------------------------------------------------------
Monetary    Zero     2000             $50,000    4/21/2016  ZERO
             The      Joseph                                 Prostate
             Projec   E                                      Cancer Run/
             t To     Sanker                                 Walk
             End      BLVD                                   National
             Prosta   Norwood                                Series--Nat
             te       , OH                                   ionwide
             Cancer   45212
------------------------------------------------------------------------
Janssen has also made financial donations to independent charitable
  foundations that assist patients who are underinsured and in financial
  need with treatment-related expenses. In keeping with our donor
  agreements and applicable regulatory guidance, we will only disclose
  aggregate data on our charitable giving and do not publicize
  information on donations to specific foundations and disease states.
  In 2016, we contributed $47 million in donations to independent
  charitable foundations, enabling them to provide assistance with
  medication-related copays to patients with cancer and autoimmune
  diseases.


----------------------------------------------------------------------------------------------------------------
 
----------------------------------------------------------------------------------------------------------------
Product               Johnson & Johnson     One Johnson &          $71,016,839    3/31/2016  Patient Assistance
                       Patient Assistance    Johnson Plaza New                                Product Donation
                       Foundation            Brunswick, NJ 08933
----------------------------------------------------------------------------------------------------------------
Product               Johnson & Johnson     One Johnson &          $58,963,086    6/30/2016  Patient Assistance
                       Patient Assistance    Johnson Plaza New                                Product Donation
                       Foundation            Brunswick, NJ 08934
----------------------------------------------------------------------------------------------------------------
Product               Johnson & Johnson     One Johnson &          $60,107,176    9/30/2016  Patient Assistance
                       Patient Assistance    Johnson Plaza New                                Product Donation
                       Foundation            Brunswick, NJ 08935
----------------------------------------------------------------------------------------------------------------
Product               Johnson & Johnson     One Johnson &           99,129,337  $12/31/2016  Patient Assistance
                       Patient Assistance    Johnson Plaza New                                Product Donation
                       Foundation            Brunswick, NJ 08936
----------------------------------------------------------------------------------------------------------------
Updated March 30, 2017


Janssen Pharmaceuticals, Inc. Monetary and Product Contribution to U.S.-
              based Charitable Organizations Full Year 2016
        (Payments made from January 1, 2016 to December 31, 2016)
------------------------------------------------------------------------
                                                               Project
 Donation    Payee     Payee   Payment Amount    Payment       Title/
   Type               Address       (USD)         Date      Description
------------------------------------------------------------------------
Monetary    180      1                 $1,000   12/15/2016  2NDFLOOR
             Turnin   Bethany                                Youth
             g        Road,                                  Helpline
             Lives    Buildin                                Hunterdon,
             Around   g 3                                    Mercer, and
             Inc.     Suite                                  Somerset
                      42                                     Operations
                      Hazlet,
                      NJ
                      07730
------------------------------------------------------------------------
Monetary    Alzheim  225 N.            $5,000   12/15/2016  Comfort Zone
             er's     Michiga                                Program
             Associ   n                                      Support
             ation    Avenue
                      Chicago
                      , IL
                      60601
------------------------------------------------------------------------
Monetary    America  4100             $20,000    12/7/2016  General
             n        Alpha                                  mission
             Diabet   Road,                                  support
             es       Suite
             Associ   100
             ation    Dallas,
                      TX
                      75244
------------------------------------------------------------------------
Monetary    America  1160             $10,000    7/11/2016  What Can I
             n        Route                                  Eat?
             Diabet   22
             es       East,
             Associ   Suite
             ation    103
                      Bridgew
                      ater,
                      NJ
                      08807
------------------------------------------------------------------------
Monetary    America  PO Box           $30,000   12/23/2016  Atrial
             n        541                                    Fibrillatio
             Founda   Greenwo                                n Patient
             tion     od, TX                                 Education
             For      76246                                  and Support
             Womens
             Health
------------------------------------------------------------------------
Monetary    America  1 Union           $5,000   12/23/2016  Garden State
             n        Street                                 Go Red For
             Heart    Suite                                  Women
             Associ   301                                    Luncheon
             ation-   Robbins
             -New     ville,
             Jersey   NJ
                      08691
------------------------------------------------------------------------
Monetary    America  1000            $100,000   12/15/2016  Typical or
             n        Wilson                                 Troubled?
             Psychi   Blvd,                                  School-
             atric    Suite                                  Based
             Founda   1825                                   Mental
             tion     Arlingt                                Health
                      on, VA                                 Education
                      22209                                  Program
------------------------------------------------------------------------
Monetary    America  1000            $200,000   12/15/2016  Judges' and
             n        Wilson                                 Psychiatris
             Psychi   Blvd,                                  ts'
             atric    Suite                                  Leadership
             Founda   1825                                   Initiative
             tion     Arlingt                                previously
                      on, VA                                 known as
                      22209                                  Judges'
                                                             Leadership
                                                             Initiative
                                                             (JLI)
------------------------------------------------------------------------
Monetary    America  1000             $35,000   12/15/2016  Partnership
             n        Wilson                                 for
             Psychi   Blvd,                                  Workplace
             atric    Suite                                  Mental
             Founda   1825                                   Health
             tion     Arlingt
                      on, VA
                      22209
------------------------------------------------------------------------
Monetary    America  150                 $300    9/27/2016  Costs
             's       Pittsto                                associated
             Grow-A-  wn Road                                with 2016
             Row,     Pittsto                                Janssen
             Inc.     wn, NJ                                 Cares
                      08867                                  Volunteer
                                                             Activity
------------------------------------------------------------------------
Monetary    Anchor   482                 $743    1/19/2016  General
             House,   Centre                                 Operating
             Inc.     Street                                 Support
                      Trenton
                      , NJ
                      08611
------------------------------------------------------------------------
Monetary    Anderso  PO Box           $20,000    12/7/2016  Integrated
             n        134 532                                Care
             House    Route                                  Management
                      523
                      Whiteho
                      use
                      Station
                      , NJ
                      08889
------------------------------------------------------------------------
Monetary    Ann      595 W.            $9,500   12/15/2016  Improving
             Silver   State                                  Patient
             man      Street                                 Self-Care
             Commun   Doylest                                and
             ity      own, PA                                Management
             Health   18901                                  of Chronic
             Clinic                                          Illnesses
                                                             at a Free
                                                             Clinic for
                                                             the
                                                             Uninsured.
------------------------------------------------------------------------
Monetary    Arbor    211                  $75    5/17/2016  Employee
             Day      North                                  directed
             Founda   12th St                                donation in
             tion     Lincoln                                lieu of
                      , NE                                   company
                      68508                                  holiday
                                                             gift
------------------------------------------------------------------------
Monetary    Arc of   141               $3,000    9/28/2016  Day Care
             Somers   South                                  subsidies
             et       Main                                   for at risk
             County   Street                                 children
                      Manvill                                and
                      e, NJ                                  children
                      08835                                  with
                                                             disabilitie
                                                             s
------------------------------------------------------------------------
Monetary    Asian    180 W             $2,000     4/6/2016  Cardiovascul
             Health   Washing                                ar Health
             Coalit   ton St                                 Screenings
             ion      Suite                                  for Low-
                      1000                                   Income at-
                      Chicago                                risk Asians
                      , IL                                   Immigrants
                      60602                                  and
                                                             Refugees in
                                                             Chicago
------------------------------------------------------------------------
Monetary    Bay      66 Canal          $5,000    6/24/2016  Bay Cove
             Cove     Street                                 Wellness
             Human    Boston,                                Center
             Servic   MA
             es,      02114
             Inc.
------------------------------------------------------------------------
Monetary    Bear     1162                $750   12/15/2016  The Bear
             Tavern   Bear                                   Tavern
             Parent   Tavern                                 Science
             s        Road                                   Fair
             Associ   Titusvi
             ation    lle, NJ
                      08560
------------------------------------------------------------------------
Monetary    Bear     1162                $750     3/1/2016  Bear Tavern
             Tavern   Bear                                   Elementary
             Parent   Tavern                                 School
             s        Road                                   Science
             Associ   Titusvi                                Fair
             ation    lle, NJ
                      08560
------------------------------------------------------------------------
Monetary    Big      2875              $6,500   11/18/2016  STEM School
             Brothe   York                                   Mentoring
             rs Big   Road                                   Initiative
             Sister   Jamison
             s of     , PA
             Bucks    18929
             County
------------------------------------------------------------------------
Monetary    Big      535 East          $7,500   11/18/2016  Youth
             Brothe   Frankli                                Mentoring
             rs Big   n                                      Programs
             Sister   Street
             s of     Trenton
             Mercer   , NJ
             County   08610
------------------------------------------------------------------------
Monetary    Boys     212              $20,000   12/15/2016  Extended Day
             and      Centre                                 Learning
             Girls    Street
             Club     Trenton
             of       , NJ
             Trento   08611
             n and
             Mercer
             County
------------------------------------------------------------------------
Monetary    Bristol  120               $7,500   12/15/2016  ArtRageous
             Rivers   Radclif                                Theatre
             ide      fe                                     Arts
             Theate   Street                                 Education
             r Co     Bristol                                Program
             Inc.     , PA
                      19007
------------------------------------------------------------------------
Monetary    Broward  305 SE           $15,000     8/4/2016  Affordable
             County   18th                                   Housing
             Commun   Court                                  program
             ity      Fort
             Develo   Lauderd
             pment    ale, FL
             Corpor   33316
             ation
             , Inc.
------------------------------------------------------------------------
Monetary    Bucks    1069              $5,000   12/15/2016  Veterans
             County   Jackson                                Housing
             Housin   ville                                  Assistance
             g        Road                                   Program
             Group    Ivyland
                      , PA
                      18974
------------------------------------------------------------------------
Monetary    Califor  2015             $25,000    4/11/2016  Using
             nia      Steiner                                Community
             Pacifi   Street                                 Health
             c        San                                    Workers to
             Medica   Francis                                increase
             l        co, CA                                 underserved
             Center   94115                                  patients'
             Founda                                          ability to
             tion                                            manage type
                                                             2 diabetes.
------------------------------------------------------------------------
Monetary    Caminar  2600 S.           $7,500    4/12/2016  Bridges to
                      El                                     Wellness
                      Camino
                      Real,
                      Suite
                      200 San
                      Mateo,
                      CA
                      94403
------------------------------------------------------------------------
Monetary    Cardiov  PO Box            $5,000    3/31/2016  25th Annual
             ascula   54632                                  Lansdale
             r        Philade                                Internation
             Instit   lphia,                                 al Spring
             ute of   PA                                     Festival
             Philad   19148
             elphia
------------------------------------------------------------------------
Monetary    Catholi  25 Ikea           $4,000   12/22/2016  Catholic
             c        Drive                                  Charities,
             Charit   Westham                                Diocese of
             ies      pton,                                  Trenton On
                      NJ                                     My Own--
                      08060                                  Supportive
                                                             Housing
                                                             Program
                                                             Services
------------------------------------------------------------------------
Monetary    Catholi  25 Ikea          $15,000   12/22/2016  Partners in
             c        Drive                                  Recovery
             Charit   Westham                                program
             ies      pton,
                      NJ
                      08060
------------------------------------------------------------------------
Monetary    Catholi  212                  $75    1/19/2016  Employee
             c        Ninth                                  directed
             Charit   Street                                 donation in
             ies      Pittsbu                                lieu of
             Dioces   rgh,                                   company
             e of     Pennsyl                                holiday
             Pittsb   vania                                  gift
             urgh     15222
------------------------------------------------------------------------
Monetary    Catholi  920               $4,000   11/18/2016  CYO's Broad
             c        South                                  St. Trenton
             Youth    Broad                                  Center
             Organi   Street                                 After
             zation   Trenton                                School
             of       , NJ                                   Program
             Mercer   08611                                  (ASP)
             County                                          Tutoring
                                                             Project
------------------------------------------------------------------------
Monetary    Catholi  920                 $600   10/19/2016  Costs
             c        South                                  associated
             Youth    Broad                                  with 2016
             Organi   Street                                 Janssen
             zation   Trenton                                Cares
             of       , NJ                                   Volunteer
             Mercer   08611                                  Activity--(
             County                                          2
                                                             Activities)
------------------------------------------------------------------------
Monetary    Center   11               $10,000   10/24/2016  Community
             for      Minneak                                Based Work
             Educat   oning                                  Assessments
             ional    Road
             Advanc   Fleming
             ement    ton, NJ
                      08822
------------------------------------------------------------------------
Monetary    Center   11                  $300    11/3/2016  Costs
             for      Minneak                                associated
             Educat   oning                                  with 2016
             ional    Road                                   Janssen
             Advanc   Fleming                                Cares
             ement    ton, NJ                                Volunteer
                      08822                                  Activity
------------------------------------------------------------------------
Monetary    Childre  635                 $300   11/19/2016  Costs
             n's      South                                  associated
             Home     Clinton                                with 2016
             Societ   Avenue                                 Janssen
             y of     Trenton                                Cares
             New      , NJ                                   Volunteer
             Jersey   08611                                  Activity
------------------------------------------------------------------------
Monetary    Childre  635              $10,000   11/22/2016  CUNA and
             n's      South                                  Body and
             Home     Clinton                                Soul
             Societ   Avenue                                 Prenatal
             y of     Trenton                                Health
             New      , NJ                                   Education
             Jersey   08611                                  Program
------------------------------------------------------------------------
Monetary    Clevela  9500             $25,000    8/19/2016  Diabetes
             nd       Euclid                                 Center
             Clinic   Ave.                                   Educational
             Educat   Clevela                                Initiatives
             ional    nd, OH                                 at
             Founda   44195                                  Cleveland
             tion                                            Clinic
                                                             South
                                                             Pointe
                                                             Hospital
------------------------------------------------------------------------
Monetary    College  50 Milk          $20,000   12/21/2016  Establishing
             Diabet   St 16th                                Best
             es       Floor                                  Practices,
             Networ   Boston,                                Policies,
             k Inc.   MA                                     and
                      02109                                  Interventio
                                                             ns
------------------------------------------------------------------------
Monetary    College  2000             $20,000   11/22/2016  Nursing
             of New   Penning                                Merit
             Jersey   ton                                    Scholarship
                      Road                                   s ($7,500)
                      P.O.                                   and
                      Box                                    Educational
                      7718                                   Opportunity
                      Ewing,                                 Fund
                      NJ                                     Promise
                      08628                                  Awards
                                                             ($12,500)
------------------------------------------------------------------------
Monetary    College  2000              $5,000   11/22/2016  TCNJ Stress
             of New   Penning                                Management
             Jersey   ton                                    and Mental
                      Road                                   Health Days
                      P.O.
                      Box
                      7718
                      Ewing,
                      NJ
                      08628
------------------------------------------------------------------------
Monetary    Colorad  915 E.            $3,000     8/9/2016  Wellness
             o        9th                                    Recovery
             Mental   Avenue                                 Action
             Wellne   Denver,                                Planning
             ss       CO                                     Program
             Networ   80218
             k
------------------------------------------------------------------------
Monetary    Communi  PO Box            $5,000   12/15/2016  Rise Summer
             ty       88 116                                 Healthy
             Action   North                                  Food
             Servic   Main                                   Initiative
             e        Street                                 for low
             Center   Hightst                                income
             , Inc.   own, NJ                                youth.
                      08520
------------------------------------------------------------------------
Monetary    Communi  4059              $5,000     3/1/2016  Arts for
             ty       Skyron                                 Seniors
             Conser   Drive                                  ($3,000)
             vatory   Doylest                                and Music
             of       own, PA                                Therapy
             Music    18902                                  ($2,000)
------------------------------------------------------------------------
Monetary    Communi  PO Box          $250,000   12/21/2016  Janssen
             ty       338                                    Pharmaceuti
             Founda   Morrist                                cal
             tion     own, NJ                                Companies
             of New   07963                                  Contributio
             Jersey                                          n Fund
------------------------------------------------------------------------
Monetary    Communi  PO Box           $60,000   12/21/2016  HealtheVoice
             ty       338                                    s Impact
             Founda   Morrist                                Fund
             tion     own, NJ
             of New   07963
             Jersey
------------------------------------------------------------------------
Monetary    Communi  PO Box          $125,000    12/7/2016  Healthcare
             ty       338                                    and Basic
             Founda   Morrist                                Needs Fund
             tion     own, NJ
             of New   07963
             Jersey
------------------------------------------------------------------------
Monetary    Communi  315                  $75    5/27/2016  Employee
             ty       Losher                                 directed
             Founda   Street                                 donation in
             tion     Suite                                  lieu of
             of       100                                    Company
             Northw   Hernand                                Holiday
             est      o, MS                                  gift
             Missis   38632
             sippi
------------------------------------------------------------------------
Monetary    Communi  959               $2,000    3/10/2016  General
             ty       Route                                  Operating
             Hope,    46                                     Support
             Inc.     East,
                      Suite
                      402
                      Parsipp
                      any, NJ
                      07054
------------------------------------------------------------------------
Monetary    Communi  959              $15,000   11/15/2016  Hope for
             ty       Route                                  Veterans
             Hope,    46                                     and Valley
             Inc.     East,                                  Brook
                      Suite                                  Village for
                      402                                    Veterans
                      Parsipp
                      any, NJ
                      07054
------------------------------------------------------------------------
Monetary    Communi  959              $11,000    5/16/2016  Pathway to
             ty       Route                                  Recovery
             Hope,    46                                     Residential
             Inc.     East,                                  Programs
                      Suite                                  ($10,000)
                      402                                    The Annual
                      Parsipp                                Forum and
                      any, NJ                                Wellness
                      07054                                  Fair
                                                             ($1,000)
------------------------------------------------------------------------
Monetary    Compeer  259               $2,500    5/30/2016  Youth and
             Roches   Monroe                                 Family
             ter,     Avenue                                 Mentoring--
             Inc.     Rochest                                Family Peer
                      er, NY                                 Advocate
                      14607                                  Services
------------------------------------------------------------------------
Monetary    Contact  60 South          $1,000   10/20/2016  Fundraising
             of       Main                                   event
             Mercer   Street                                 support to
             County   Penning                                benefit
             New      ton, NJ                                general
             Jersey   08534                                  mission of
             Inc.                                            organizatio
                                                             n
------------------------------------------------------------------------
Monetary    Contact  60 South          $8,500   12/15/2016  Crisis and
             Of       Main                                   Suicide
             Mercer   Street                                 Prevention
             County   Penning                                HOTLINES,
             New      ton, NJ                                Telephone
             Jersey   08534                                  and Online:
             Inc.                                            Crisis Chat
                                                             and
                                                             TxtToday
------------------------------------------------------------------------
Monetary    CONTACT  P.O. Box          $3,500    4/12/2016  Training
             We       2376                                   Nonprofessi
             Care,    Westfie                                onals in
             Inc.     ld, NJ                                 Crisis
                      07091                                  Interventio
                                                             n for
                                                             People
                                                             Experiencin
                                                             g Psychosis
------------------------------------------------------------------------
Monetary    Court    1450             $15,000   12/15/2016  CASA of
             Appoin   Parksid                                Mercer
             ted      e                                      County
             Specia   Avenue,                                Child
             l        Suite                                  Advocacy
             Advoca   22                                     Program for
             tes      Ewing,                                 Abused and
                      NJ                                     Neglected
                      08638-                                 Children
                      2946
------------------------------------------------------------------------
Monetary    Curtain  1483              $5,000   12/19/2016  Deaf and
             Up       Rte.                                   Hard of
             Produc   179                                    Hearing
             tions    Lambert                                Access for
             Inc.     ville,                                 Curtain Up
                      NJ                                     Productions
                      08530
------------------------------------------------------------------------
Monetary    Daytop   80 West           $2,000   11/15/2016  Work
             Villag   Main St                                Readiness
             e Of     Mendham
             New      , NJ
             Jersey   07945
             Inc.
------------------------------------------------------------------------
Monetary    Deborah  212               $2,000   11/14/2016  2017 Women's
             Hospit   Trenton                                Heart
             al       Road                                   Health
             Founda   Browns                                 Symposium
             tion     Mills,
                      NJ
                      08015
------------------------------------------------------------------------
Monetary    Delawar  14                  $300   10/19/2016  Costs
             e        Michael                                associated
             River    McCorri                                with 2016
             Steamb   stin                                   Janssen
             oat      Road                                   Cares
             Floati   Hamilto                                Volunteer
             ng       n, NJ                                  Activity
             Classr   08690
             oom,
             Inc.
------------------------------------------------------------------------
Monetary    Depress  C/O                 $750     3/1/2016  DBSA NJ
             ion      David                                  Annual
             and      Mizenko                                Conference
             Bipola   5                                      for Support
             r        Village                                Group
             Suppor   Ct                                     Participant
             t        Lawrenc                                s--July,
             Allian   eville,                                2016
             ce       NJ
                      08648
------------------------------------------------------------------------
Monetary    Depress  C/O                 $750     3/1/2016  DBSA NJ
             ion      David                                  Mutual Aid
             and      Mizenko                                Support
             Bipola   5                                      Group
             r        Village                                Facilitator
             Suppor   Ct                                     Training--M
             t        Lawrenc                                arch, 2016
             Allian   eville,
             ce       NJ
                      08648
------------------------------------------------------------------------
Monetary    Desert   1695 N.           $3,500    5/16/2016  Quality of
             Aids     Sunrise                                Life and
             Projec   Way                                    Wellness
             t        Palm                                   Interventio
                      Springs                                ns for
                      , CA                                   Desert AIDS
                      92262                                  Project
                                                             Clients
                                                             Living with
                                                             Schizophren
                                                             ia or
                                                             Schizoaffec
                                                             tive
                                                             Disorder
------------------------------------------------------------------------
Monetary    Diabete  319 N.           $24,000   12/22/2016  Diabetes
             s        Weber                                  Sisters'
             Sister   Road,                                  Minority
             s        pmb                                    Initiative
                      #163                                   Program
                      Bolingb
                      rook,
                      IL
                      60490
------------------------------------------------------------------------
Monetary    Direct   27 S. La          $4,600    2/18/2016  Support to
             Relief   Patera                                 improve the
                      Lane                                   lives of
                      Santa                                  people
                      Barbara                                affected by
                      , CA                                   poverty or
                      93117                                  emergency
                                                             situations
                                                             by
                                                             mobilizing
                                                             and
                                                             providing
                                                             essential
                                                             medical
                                                             resources
                                                             needed for
                                                             their care
------------------------------------------------------------------------
Monetary    Dress    3131              $9,000   10/11/2016  Women's
             for      Princet                                Empowerment
             Succes   on Pike                                Programs
             s        Bldg 4;
                      Suite
                      209
                      Lawrenc
                      eville,
                      NJ
                      08648
------------------------------------------------------------------------
Monetary    Eden     2                 $9,500   12/15/2016  Adult
             Autism   Merwick                                Employment
             Servic   Road                                   Program
             es       Princet
             Founda   on, NJ
             tion     08540
------------------------------------------------------------------------
Monetary    Emory    49 Jesse         $25,000   10/24/2016  Emory Latino
             Univer   Hill                                   Diabetes
             sity     Jr. Dr                                 Education
                      Atlanta                                Program
                      , GA                                   (ELDEP)
                      30303
------------------------------------------------------------------------
Monetary    Enable,  13                $3,000    9/12/2016  Fundraising
             Inc.     Roszel                                 event
                      Road,                                  support to
                      Suite                                  benefit
                      B110                                   general
                      Princet                                mission of
                      on, NJ                                 organizatio
                      08540                                  n
------------------------------------------------------------------------
Monetary    Enable,  13                $7,500   12/15/2016  Enable
             Inc.     Roszel                                 Connect--Ca
                      Road,                                  mpus
                      Suite                                  Volunteer
                      B110                                   Program
                      Princet
                      on, NJ
                      08540
------------------------------------------------------------------------
Monetary    Every    Fred              $9,000   12/15/2016  Every Child
             Child    Vereen,                                Valued
             Valued   Jr.                                    (ECV) After
             A NJ     Communi                                School
             Nonpro   ty                                     Program
             fit      Center
             Corpor   175
             ation    Johnson
                      Avenue
                      Lawrenc
                      eville,
                      NJ
                      08648
------------------------------------------------------------------------
Monetary    Everybo  707               $7,500   12/15/2016  Coming Up
             dy       Alexand                                for AIRTM
             Loves    er
             Kenny    Road,
             Projec   Suite
             t Inc.   208 PO
                      Box
                      3127
                      Princet
                      on, NJ
                      08543
------------------------------------------------------------------------
Monetary    Family   1931             $10,000   12/21/2016  Family
             Guidan   Notting                                Campus
             ce       ham Way                                Project--Ho
             Center   Hamilto                                meFront
             Corpor   n, NJ                                  Collaborati
             ation    08619                                  on
------------------------------------------------------------------------
Monetary    Family   1931                $600   10/19/2016  Costs
             Guidan   Notting                                associated
             ce       ham Way                                with 2016
             Center   Hamilto                                Janssen
             Corpor   n, NJ                                  Cares
             ation    08619                                  Volunteer
                                                             Activities
------------------------------------------------------------------------
Monetary    Family   1 AAA            $14,790   12/13/2016  Center on
             Resour   Dr.                                    Nutrition
             ce       Suite                                  and
             Networ   203                                    Disability-
             k        Trenton                                -Diabetes
                      , NJ                                   Prevention
                      08691                                  and Self
                                                             Management
                                                             Program
------------------------------------------------------------------------
Monetary    Family   4                $10,000   12/15/2016  Nurse
             Servic   Corners                                Educator
             e        tone                                   for
             Associ   Drive                                  Homeless
             ation    Langhor                                Shelter
             of       ne, PA
             Bucks    19047
             County
------------------------------------------------------------------------
Monetary    Federat  One               $2,000    4/11/2016  Big Nosh
             ion of   Farming                                Vocational
             Organi   dale                                   Services
             zation   Road                                   Program
             s        West
                      Babylon
                      , NY
                      11704
------------------------------------------------------------------------
Monetary    Feed     Central              $75    1/19/2016  Employee
             More,    Virgini                                directed
             Inc.     a Food                                 donation in
                      Bank                                   lieu of
                      1415                                   company
                      Rhoadmi                                holiday
                      ller                                   gift
                      Street
                      Richmon
                      d, VA
                      23220
------------------------------------------------------------------------
Monetary    Feeding  National         $32,200    2/18/2016  Domestic
             Americ   Office                                 hunger
             a        35 East                                relief
                      Wacker                                 efforts--me
                      Drive                                  al program
                      Suite
                      2000
                      Chicago
                      , IL
                      6618
------------------------------------------------------------------------
Monetary    Fleming  110                 $300    9/15/2016  Costs
             ton      Broad                                  associated
             Area     Street                                 with 2016
             Food     Box 783                                Janssen
             Pantry   Fleming                                Cares
                      ton, NJ                                Volunteer
                      08822                                  Activity
------------------------------------------------------------------------
Monetary    Foundat  2381              $2,500   12/15/2016  Funding
             ion of   Lawrenc                                support for
             Morris   eville                                 the 2017
             Hall/    Road                                   Philly Pops
             St.      Lawrenc                                Benefit
             Lawren   eville,                                Concert
             ce       NJ
                      08648
------------------------------------------------------------------------
Monetary    Foundat  2381              $7,000   12/15/2016  Music and
             ion of   Lawrenc                                Memory
             Morris   eville
             Hall/    Road
             St.      Lawrenc
             Lawren   eville,
             ce       NJ
                      08648
------------------------------------------------------------------------
Monetary    Fountai  425 West          $6,000    9/13/2016  2016 Mad
             n        47th                                   About Art
             House    Street                                 Auction and
                      New                                    Benefit
                      York,
                      NY
                      10036
------------------------------------------------------------------------
Monetary    Fountai  425 West          $1,000    3/11/2016  Silver
             n        47th                                   sponsor
             House    Street                                 Fountain
                      New                                    House One-
                      York,                                  in-Four 5K--
                      NY                                     April 9,
                      10036                                  2016
------------------------------------------------------------------------
Monetary    From     1455             $12,500     8/4/2016  N.O.S. Film
             The      Mandala                                Project
             Heart    y Beach
             Produc   Road
             tions    Oxnard
             Inc.     Shores,
                      CA
                      93035
------------------------------------------------------------------------
Monetary    Gateway  11901            $10,000    5/19/2016  Community
             Homes,   Reedy                                  Reintegrati
             Inc.     Branch                                 on:
                      Road PO                                Maximizing
                      Box 460                                Work
                      Chester                                Readiness
                      field,                                 and
                      VA                                     Independenc
                      23838                                  e for Those
                                                             with
                                                             Schizophren
                                                             ia and
                                                             Schizoaffec
                                                             tive
                                                             Disorder
------------------------------------------------------------------------
Monetary    Georgia  246               $1,500     8/4/2016  Consumer
             Mental   Sycamor                                Scholarship
             Health   e St.                                  s to attend
             Consum   Suite                                  the 25th
             er       260                                    Annual
             Networ   Decatur                                Statewide
             k        , GA                                   Consumer
                      30030                                  Conference
------------------------------------------------------------------------
Monetary    Girl     1171              $2,000   12/23/2016  Science,
             Scouts   Route                                  Technology,
             Heart    28                                     Engineering
             of New   North                                  and Math
             Jersey   Branch,                                (STEM)
             , Inc.   NJ                                     Program
                      08876
------------------------------------------------------------------------
Monetary    Grounds  80                $7,500   12/15/2016  Wellness
             for      Sculpto                                Walks/
             Sculpt   rs Way                                 Wellness
             ure      Hamilto                                Talks for
                      n, NJ                                  Fixed
                      08619                                  Income
                                                             Seniors
------------------------------------------------------------------------
Monetary    Habitat  31 Oak            $5,000   12/15/2016  Women Build
             for      Ave                                    and Repair
             Humani   Chalfon                                Homes that
             ty of    t, PA                                  Strengthen
             Greate   18914                                  Families
             r
             Bucks
------------------------------------------------------------------------
Monetary    Habitat  212 Yost            $500    11/3/2016  Costs
             for      Bouleva                                associated
             Humani   rd                                     with 2016
             ty of    Suite A                                Janssen
             Greate   Pittsbu                                Cares
             r        rgh, PA                                Volunteer
             Pittsb   15221                                  Activity
             urgh
------------------------------------------------------------------------
Monetary    HARK,    5                 $2,000   12/15/2016  Scholarships
             Inc.     Pirozzi                                for low-
                      Lane                                   income
                      Hillsbo                                participant
                      rough,                                 s in Girls
                      NJ                                     on the Run
                      08844                                  of Central
                                                             New Jersey
------------------------------------------------------------------------
Monetary    Heartla  4750 N.           $7,500    5/30/2016  Pathways
             nd       Sherida                                Home
             Health   n Road
             Outrea   Chicago
             ch       , IL
                      60640
------------------------------------------------------------------------
Monetary    Henders  4740              $7,500    4/12/2016  Helping
             on       North                                  Individuals
             Behavi   State                                  Live Longer
             oral     Road 7                                 (HILL)
             Health   Lauderd
                      ale
                      Lakes,
                      FL
                      33319
------------------------------------------------------------------------
Monetary    Henry    321               $7,500   12/21/2016  Decreasing
             J.       North                                  Opioid Use
             Austin   Warren                                 through
             Health   Street                                 Patient
             Center   Trenton                                Empowerment
             , Inc.   , NJ                                   and
                      08618                                  Chiropracto
                                                             r Services
------------------------------------------------------------------------
Monetary    His      20000 NW            $600    1/18/2016  Employee
             House    47th                                   directed
             Childr   Avenue                                 donation in
             en's     Hector                                 lieu of
             Home     Buildin                                company
                      g No. 2                                holiday
                      Develop                                gift
                      ment
                      Departm
                      ent
                      Miami
                      Gardens
                      , FL
                      33055
------------------------------------------------------------------------
Monetary    HiTops,  21                $7,500    9/12/2016  HiTOPS'
             Inc.     Wiggins                                Sexual
                      Street                                 Health
                      Princet                                Interventio
                      on, NJ                                 ns for
                      08540                                  Youth-at-
                                                             Risk
------------------------------------------------------------------------
Monetary    Holiday  968               $4,000    9/29/2016  Holiday
             Expres   Shrewsb                                Express
             s Inc.   ury                                    Central
                      Avenue                                 Jersey
                      Tinton                                 Charity
                      Falls,                                 Concert
                      NJ                                     Series
                      07724
------------------------------------------------------------------------
Monetary    HomeFro  1880              $2,500    9/12/2016  Fundraising
             nt       Princet                                event
                      on                                     support to
                      Avenue                                 benefit
                      Lawrenc                                general
                      eville,                                mission of
                      NJ                                     organizatio
                      08648                                  n
------------------------------------------------------------------------
Monetary    HomeFro  1880             $10,000   10/26/2016  Breaking the
             nt       Princet                                Cycle of
                      on                                     Poverty for
                      Avenue                                 Homeless
                      Lawrenc                                Families
                      eville,
                      NJ
                      08648
------------------------------------------------------------------------
Monetary    HomeFro  1880                $300   10/20/2016  Costs
             nt       Princet                                associated
                      on                                     with 2016
                      Avenue                                 Janssen
                      Lawrenc                                Cares event
                      eville,
                      NJ
                      08648
------------------------------------------------------------------------
Monetary    Hopewel  35                  $750   12/15/2016  Hopewell
             l        Princet                                Elementary
             Elemen   on                                     School
             tary     Avenue                                 Science
             School   Hopewel                                Fair
             Parent   l, NJ
             Teache   08525
             r
             Organi
             zation
             Inc.
------------------------------------------------------------------------
Monetary    Hopewel  PO Box            $6,500   12/15/2016  (1) College
             l        553                                    Scholarship
             Valley   Penning                                ($1,000)
             Educat   ton, NJ                                (2)
             ion      08534                                  Hopewell
             Founda                                          Valley HOSA
             tion                                            ($500) (3)
                                                             Teaching
                                                             the Stars--
                                                             Using
                                                             Starlab to
                                                             enhance
                                                             curricula
                                                             in the
                                                             HVRSD
                                                             ($5,000)
------------------------------------------------------------------------
Monetary    Hopewel  PO Box            $1,000     5/2/2016  Scholarship
             l        553                                    support
             Valley   Penning
             Educat   ton, NJ
             ion      08534
             Founda
             tion
------------------------------------------------------------------------
Monetary    Hopewel  48                $2,000   12/21/2016  Hopewell
             l        Orchard                                Valley
             Valley   Ave PO                                 Rides
             Senior   Box 567
             Founda   Penning
             tion     ton, NJ
                      08534
------------------------------------------------------------------------
Monetary    Hunterd  7 Lower           $7,500   12/21/2016  Artistic
             on Art   Center                                 Expressions
             Center   Street                                 Program
                      Clinton
                      , NJ
                      08809
------------------------------------------------------------------------
Monetary    Hunterd  1410              $2,500    11/9/2016  YMCA Comedy
             on       Route                                  Night
             County   22 West
             YMCA     Annanda
                      le, NJ
                      08801
------------------------------------------------------------------------
Monetary    Hunterd  9100                $100    1/19/2016  Memorial
             on       Wescott                                Donation
             Health   Drive
             care     Suite
             Founda   202
             tion     Fleming
                      ton, NJ
                      08822
------------------------------------------------------------------------
Monetary    Hunterd  111 Mine          $2,000   12/15/2016  Dvoor Farm
             on       Street                                 Public
             Land     Fleming                                Access
             Trust    ton, NJ                                Enhancement
                      08822
------------------------------------------------------------------------
Monetary    HVRSD    C/O               $5,000   12/22/2016  Playground
             Specia   Pupil                                  resurfacing
             l        Service                                project
             Educat   s 425                                  Stonybrook
             ion      South                                  Elementary
             PtO      Main
                      Street
                      Penning
                      ton, NJ
                      08534
------------------------------------------------------------------------
Monetary    Interfa  3635             $15,000   10/26/2016  Neighbors
             ith      Quakerb                                Helping
             Caregi   ridege                                 Neighbors
             vers     Road,                                  Program
             Trento   Suite                                  (NHN)
             n,       16
             Inc.     Hamilto
                      n, NJ
                      08619
------------------------------------------------------------------------
Monetary    Isles,   10 Wood           $9,000   12/15/2016  Trenton
             Inc.     Street                                 Healthy
                      Trenton                                Homes
                      , NJ
                      08618
------------------------------------------------------------------------
Monetary    Jewish   707               $7,500   11/22/2016  Mercer
             Family   Alexand                                County
             and      er                                     Caregiver
             Childr   Road,                                  Support
             en's     Suite                                  Initiative
             Servic   102
             e of     Princet
             Greate   on, NJ
             r        08540
             Mercer
             County
------------------------------------------------------------------------
Monetary    Jewish   707               $7,500   11/22/2016  Senior
             Family   Alexand                                Outreach
             and      er                                     Service
             Childr   Road,
             en's     Suite
             Servic   102
             e of     Princet
             Greate   on, NJ
             r        08540
             Mercer
             County
------------------------------------------------------------------------
Monetary    Jewish   707                 $600   10/19/2016  Costs
             Family   Alexand                                associated
             and      er                                     with 2016
             Childr   Road,                                  Janssen
             en's     Suite                                  Cares
             Servic   102                                    Volunteer
             e of     Princet                                Activities
             Greate   on, NJ
             r        08540
             Mercer
             County
------------------------------------------------------------------------
Monetary    Junior   360 Pear          $7,150   12/21/2016  Junior
             Achiev   Blossom                                Achievement
             ement    Drive                                  program in
             of New   Edison,                                Trenton
             Jersey   NJ                                     Schools
                      08837
------------------------------------------------------------------------
Monetary    Lafayet  1214             $30,000     1/6/2016  The Healthy
             te       Coolidg                                Heart
             Genera   e                                      Fairs: EKG
             l        Street                                 to
             Medica   Lafayet                                Survivorshi
             l        te, LA                                 p Program
                      70503
------------------------------------------------------------------------
Monetary    Latin    669               $5,000   12/16/2016  Welcome
             Americ   Chamber                                House
             an       s St                                   Community
             Legal    Suite B                                Center
             Defens   Trenton
             e And    , NJ
             Educat   08611
             ional
             Fund
             Inc.
------------------------------------------------------------------------
Monetary    Lawrenc  PO Box            $3,900   12/15/2016  Mobile
             e        6531 17                                Makerspaces
             Townsh   Philips                                to create,
             ip       Ave.                                   build,
             Educat   Lawrenc                                tinker,
             ion      eville,                                fail and
             Founda   NJ                                     think
             tion     08648                                  critically
             Inc.                                            from
                                                             elementary
                                                             classrooms
                                                             in Lawrence
                                                             Township,
                                                             NJ.
------------------------------------------------------------------------
Monetary    Leyden   10001 W           $8,500    5/16/2016  Affordable
             Family   Grand                                  Supportive
             Servic   Ave                                    Housing for
             e and    Frankli                                Individuals
             Mental   n Park,                                with
             Health   IL                                     Serious
             Center   60131                                  Mental
                                                             Illness
------------------------------------------------------------------------
Monetary    Literac  PO Box            $5,000   12/21/2016  Early
             y And    55636                                  Childhood:
             Life     Trenton                                Building
             Inc.     , NJ                                   Blocks for
                      08638                                  the Future
------------------------------------------------------------------------
Monetary    Literac  100               $5,000   12/22/2016  Women
             y New    Menlo                                  Empowered
             Jersey   Park
             Inc.     Dr.
                      #314
                      Edison,
                      NJ
                      08837
------------------------------------------------------------------------
Monetary    Literac  120               $4,000   12/15/2016  Let's Talk
             y        Findern                                About
             Volunt   e Ave--                                Health
             eers     Box 7
             of       Bridgew
             Somers   ater,
             et       NJ
             County   08807
------------------------------------------------------------------------
Monetary    Main     8                 $4,000    4/12/2016  Accessible
             Street   Marcell                                Mental
             Counse   a                                      Health Care
             ling     Avenue                                 for
             Center   West                                   Schizoaffec
                      Orange,                                tive
                      NJ                                     Disorder
                      07052
------------------------------------------------------------------------
Monetary    Massach  15                $3,500     2/9/2016  Changing
             usetts   Vernon                                 Minds and
             Clubho   Street                                 Expanding
             use      Waltham                                Employment
             Coalit   , MA                                   Campaign
             ion      02453
------------------------------------------------------------------------
Monetary    McCarte  91               $10,000   11/22/2016  OnStage
             r        Univers                                Seniors: A
             Theatr   ity                                    Community
             e        Place                                  Project of
             Center   Princet                                McCarter
                      on, NJ                                 Theatre
                      08540
------------------------------------------------------------------------
Monetary    Meals    5 Walter            $300    11/3/2016  Costs
             On       Foran                                  associated
             Wheels   Blvd                                   with 2016
             In       Suite                                  Janssen
             Hunter   2006                                   Cares
             don      Fleming                                Volunteer
             Inc.     ton, NJ                                Activity
                      08822
------------------------------------------------------------------------
Monetary    Meals    1501                 $75    5/23/2016  Employee
             On       Sunset                                 directed
             Wheels   Ave                                    donation in
             of       Rocky                                  lieu of
             Rocky    Mount,                                 company
             Mount    NC                                     holiday
             Inc.     27804                                  gift
------------------------------------------------------------------------
Monetary    Meals    320              $15,000   10/26/2016  Meals on
             on       Hollowb                                Wheels
             Wheels   rook                                   Program
             of       Drive
             Trento   Ewing,
             n        NJ
             Ewing    08638
------------------------------------------------------------------------
Monetary    Mental   500              $90,000   12/15/2016  Social Self-
             Health   Montgom                                Directed
             Americ   ery St.                                Care (SSDC)
             a        Suite
                      820
                      Alexand
                      ria, VA
                      22314
------------------------------------------------------------------------
Monetary    Mental   2211              $7,500    6/21/2016  Mental
             Health   Norfolk                                Health
             Americ   , Suite                                Community
             a of     810                                    and
             Greate   Houston                                Legislative
             r        , TX                                   Advocacy
             Housto   77098
             n
------------------------------------------------------------------------
Monetary    Mental   2323 W           $10,000    5/27/2016  Get
             Health   5th                                    Connected
             Americ   Ave.                                   program
             a of     Suite
             Frankl   160
             in       Columbu
             County   s, OH
                      43204
------------------------------------------------------------------------
Monetary    Mental   8280              $2,500    8/24/2016  2016 Florida
             Health   Princet                                Mental
             Americ   on                                     Health
             a Of     Square                                 Summit
             Northe   Blvd.
             ast      W.
             Florid   Suite 8
             a Inc.   Jackson
                      ville,
                      FL
                      32256
------------------------------------------------------------------------
Monetary    Mental   1210 San          $2,500    5/16/2016  Mental
             Health   Antonio                                Health
             Americ   , Suite                                Education
             a of     200                                    and
             Texas    Austin,                                Advocacy
                      TX                                     Campaign
                      78701
------------------------------------------------------------------------
Monetary    Mental   100 W.            $1,000     8/9/2016  Bronze
             Health   10th                                   sponsor
             Associ   St.                                    2016 E-
             ation    Ste.                                   Racing the
             in       600                                    Blues for
             Delawa   Wilming                                Mental
             re       ton, DE                                Health--Oct
                      19801                                  ober 30,
                                                             2016
------------------------------------------------------------------------
Monetary    Mental   100 W.            $2,000   10/18/2016  Community
             Health   10th                                   Mental
             Associ   St.                                    Health
             ation    Ste.                                   Conference
             in       600                                    2016:
             Delawa   Wilming                                Bridging
             re       ton, DE                                the Gaps--
                      19801                                  Through
                                                             Resources
                                                             and
                                                             Networking
------------------------------------------------------------------------
Monetary    Mental   673              $10,000     8/4/2016  MHANJ Access
             Health   Morris                                 to Mental
             Associ   Avenue,                                Health Care
             ation    Suite
             in New   100
             Jersey   Springf
                      ield,
                      NJ
                      07081
------------------------------------------------------------------------
Monetary    Mental   617               $2,500    4/21/2016  Operating
             Health   Garden                                 Support for
             Associ   Street                                 the Mental
             ation    Santa                                  Wellness
             in       Barbara                                Center's
             Santa    , CA                                   Fellowship
             Barbar   93101                                  Club
             a
             County
------------------------------------------------------------------------
Monetary    Mental   3701              $7,500    5/16/2016  ParentVOICE
             Health   Latrobe
             Associ   Drive,
             ation    Suite
             Of       140
             Centra   Charlot
             l        te, NC
             Caroli   28211
             nas
             Inc.
------------------------------------------------------------------------
Monetary    Mental   1301             $10,000     8/4/2016  Citizens
             Health   York                                   Action
             Associ   Road,                                  Team:
             ation    Suite                                  Engaging
             of       505                                    Consumers
             Maryla   Lutherv                                of
             nd,      ille,                                  Behavioral
             Inc.     MD                                     Health in
                      21093                                  Healthcare
                                                             Reform
                                                             Initiatives
------------------------------------------------------------------------
Monetary    Mental   580               $1,000    3/15/2016  Bronze
             Health   White                                  sponsor MHA
             Associ   Plains                                 on the
             ation    Road                                   Move: Run/
             of       Suite                                  Walk--May
             Westch   510                                    1, 2016
             ester    Tarryto
                      wn, NY
                      10591
------------------------------------------------------------------------
Monetary    Mental   555 N             $3,500    6/24/2016  Access to
             Health   Woodlaw                                Care Fund
             Associ   n, Ste.
             ation    3105
             Reside   Wichita
             ntial    , KS
             Care     67208
             Inc.
------------------------------------------------------------------------
Monetary    Mental   3809             $12,500     8/4/2016  Outreach and
             Illnes   Rosewoo                                Behavioral
             s        d Drive                                Healthcare
             Recove   PO Box                                 for
             ry       4246                                   Homeless
             Center   Columbi                                Individuals
             , Inc.   a, SC                                  with Mental
                      29240                                  Illness
------------------------------------------------------------------------
Monetary    Mercer   1001              $9,500   12/15/2016  Implementing
             Allian   Spruce                                 a Plan to
             ce to    Street,                                End Chronic
             End      Suite                                  Homelessnes
             Homele   205                                    s in the
             ssness   Trenton                                Trenton/
                      , NJ                                   Mercer
                      08638                                  Community:
                                                             Utilizing
                                                             assertive
                                                             engagement,
                                                             permanent
                                                             housing and
                                                             healthcare
                                                             access to
                                                             achieve
                                                             this goal
------------------------------------------------------------------------
Monetary    Mercer   P.O. Box         $16,680   12/15/2016  Mercer
             County   17202                                  Student
             Commun   Trenton                                Competency
             ity      , NJ                                   in Optical
             Colleg   08690                                  Examination
             e                                               (M-SCOPE)
             Founda
             tion
------------------------------------------------------------------------
Monetary    Mercer   151              $20,000   10/26/2016  Mercer
             Street   Mercer                                 Street
             Friend   Street                                 Friends
             s        Trenton                                Food Bank
                      , NJ
                      08611
------------------------------------------------------------------------
Monetary    Mercer   151                 $300   10/19/2016  Costs
             Street   Mercer                                 associated
             Friend   Street                                 with 2016
             s        Trenton                                Janssen
                      , NJ                                   Cares
                      08611                                  Volunteer
                                                             Activity
------------------------------------------------------------------------
Monetary    Metropo  945               $5,000    7/20/2016  Supported
             litan    Fawcett                                Employment
             Develo   Ave.
             pment    Tacoma,
             Counci   WA
             l        98402
------------------------------------------------------------------------
Monetary    Middle   P.O. Box         $15,000   11/15/2016  Outreach
             Earth    8045                                   Program and
                      520                                    Community
                      North                                  Youth
                      Bridge                                 Centers
                      Street
                      Bridgew
                      ater,
                      NJ
                      08807
------------------------------------------------------------------------
Monetary    MIDJers  423               $5,000   10/26/2016  Urban Youth
             ey       Rivervi                                Employment
             Center   ew                                     Program
             for      Plaza
             Econom   Trenton
             ic       , NJ
             Develo   08611
             pment
------------------------------------------------------------------------
Monetary    Midland  60                $6,500    9/28/2016  Midland
             Adult    Industr                                Helping
             Servic   ial                                    Hands
             es       Parkway                                Employment
             Inc.     PO Box                                 Training
                      5026                                   Program.
                      North
                      Branch,
                      NJ
                      08876
------------------------------------------------------------------------
Monetary    Millhil  101               $5,000   10/26/2016  Trenton Area
             l        Oakland                                Stakeholder
             Child    Street                                 s
             and      Trenton
             Family   , NJ
                      08618
------------------------------------------------------------------------
Monetary    Millhil  101              $15,000   10/26/2016  Millhill
             l        Oakland                                Trenton
             Child    Street                                 PEERS
             and      Trenton
             Family   , NJ
                      08618
------------------------------------------------------------------------
Monetary    Minding  2083              $6,000   12/15/2016  Minding Our
             Our      Lawrenc                                Business
             Busine   eville                                 Summer
             ss       Road                                   Program: A
             Inc.     Lawrenc                                Bridge to
                      eville,                                the Future
                      NJ                                     for Mercer
                      08648                                  County Low-
                                                             Income
                                                             Youth
------------------------------------------------------------------------
Monetary    Minding  2083              $6,000     5/2/2016  Minding Our
             Our      Lawrenc                                Business
             Busine   eville                                 Summer
             ss       Road                                   Program: A
             Inc.     Lawrenc                                Bridge to
                      eville,                                the Future
                      NJ                                     for Mercer
                      08648                                  County Low-
                                                             Income
                                                             Youth
------------------------------------------------------------------------
Monetary    Morven   55                $5,000   12/15/2016  Internship
             Museum   Stockto                                for At-Risk
             and      n                                      Youth
             Garden   Street
                      Princet
                      on, NJ
                      08540
------------------------------------------------------------------------
Monetary    Mount    73 North         $15,000    9/15/2016  In Home
             Carmel   Clinton                                Health
             Guild    Avenue                                 Nursing
                      Trenton                                Program
                      , NJ
                      08609
------------------------------------------------------------------------
Monetary    NAMI     4161 NW           $1,000    4/18/2016  Bronze
             Browar   5 St,                                  sponsor
             d        Suite                                  NAMIWalks
             County   203                                    Broward
             , Inc.   Plantat                                County--Nov
                      ion, FL                                ember 12,
                      33317                                  2016
------------------------------------------------------------------------
Monetary    NAMI     8324              $1,000    3/21/2016  Bronze
             Cook     Skokie                                 sponsor
             County   Blvd                                   NAMI CCNS
             North    420                                    Walk--Septe
             Suburb   Frontag                                mber 18,
             an       e Road                                 2016
                      Northfi
                      eld
                      Skokie,
                      IL
                      60077
------------------------------------------------------------------------
Monetary    NAMI     2400 W.           $1,000    3/15/2016  Bronze
             Delawa   4th St.                                sponsor
             re       Wilming                                NAMIWalks
                      ton, DE                                Delaware--M
                      19805                                  ay 7, 2016
------------------------------------------------------------------------
Monetary    NAMI     3371              $2,500     3/1/2016  Silver
             Mercer   Brunswi                                sponsor
             NJ       ck                                     2016 NAMI
                      Pike,                                  Mercer
                      Suite                                  Walk--May
                      124                                    7, 2016
                      Lawrenc
                      eville,
                      NJ
                      08648
------------------------------------------------------------------------
Monetary    NAMI     3371             $10,000    9/15/2016  NAMI Mercer
             Mercer   Brunswi                                Education
             NJ       ck                                     and Support
                      Pike,                                  Programs
                      Suite
                      124
                      Lawrenc
                      eville,
                      NJ
                      08648
------------------------------------------------------------------------
Monetary    NAMI     85 N.             $1,000     9/7/2016  Bronze
             New      State                                  sponsor
             Hampsh   Street                                 2016
             ire      Concord                                NAMIWalks
                      , NH                                   New
                      03301                                  Hampshire--
                                                             October 2,
                                                             2016
------------------------------------------------------------------------
Monetary    NAMI of  115               $8,000     8/9/2016  Peer Support
             DuPage   North                                  Specialist
             County   County                                 Program
             Illino   Farm
             is       Road
                      Wheaton
                      , IL
                      60187
------------------------------------------------------------------------
Monetary    NAMI of  2701              $4,000    8/24/2016  General
             Johnso   Rochest                                Program
             n        er                                     Support/
             County   Avenue                                 Finds
             dba      Iowa                                   Friends/
             Compee   City,                                  Volunteer
             r of     IA                                     Recruitment
             Johnso   52245
             n
             County
------------------------------------------------------------------------
Monetary    NAMI of  One               $1,500     8/4/2016  Start to
             Lake     Victori                                Finish
             County   a Sq.,                                 sponsor
                      Ste.                                   NAMI Lake
                      260                                    County
                      Painesv                                Strides for
                      ille,                                  Awareness
                      OH                                     NAMI Walk--
                      44077                                  August 20,
                                                             2016
------------------------------------------------------------------------
Monetary    NAMI of  100 W,            $1,000    3/15/2016  Bronze
             PA       Main                                   sponsor
             Montgo   St.                                    Greater
             mery     Suite                                  Philadelphi
             County   204                                    a
                      Lansdal                                NAMIWalks--
                      e, PA                                  May 14,
                      19446                                  2016
------------------------------------------------------------------------
Monetary    NAMI of  4055              $2,500     5/4/2016  Hope for
             Southw   Executi                                Recovery
             est      ve Park                                Pilot
             Ohio     Drive,
                      Suite
                      450
                      Cincinn
                      ati, OH
                      45241
------------------------------------------------------------------------
Monetary    NAMI     1750 S.           $1,000    3/15/2016  Kilometer
             St.      Brentwo                                sponsor
             Louis    od                                     NAMIWalks
                      Blvd.                                  St. Louis--
                      Suite                                  May 28,
                      511 St.                                2016
                      Louis,
                      MO
                      63144
------------------------------------------------------------------------
Monetary    NAMI     PO Box            $1,000    4/19/2016  Bronze
             Summit   462                                    sponsor
             County   Cuyahog                                2016
                      a                                      NAMIWalks
                      Falls,                                 Summit
                      OH                                     County--Oct
                      44222                                  ober 22,
                                                             2016
------------------------------------------------------------------------
Monetary    NAMI     217               $1,000    5/27/2016  Bronze
             Waukes   Wiscons                                sponsor
             ha       in Ave                                 2016
                      Suite                                  NAMIWalks
                      300                                    Waukesha--P
                      Waukesh                                9/17/16
                      a, WI
                      53186
------------------------------------------------------------------------
Monetary    Nationa  90 Park           $2,500    5/16/2016  Meet the
             l        Avenue                                 Scientist
             Allian   16th                                   Monthly
             ce for   Floor                                  Webinar
             Resear   New                                    Series
             ch on    York,
             Schizo   NY
             phreni   10016
             a and
             Depres
             sion
------------------------------------------------------------------------
Monetary    Nationa  90 Park           $2,500    5/16/2016  28th New
             l        Avenue                                 York Mental
             Allian   16th                                   Health
             ce for   Floor                                  Research
             Resear   New                                    Symposium
             ch on    York,
             Schizo   NY
             phreni   10016
             a and
             Depres
             sion
------------------------------------------------------------------------
Monetary    Nationa  1851              $2,500     2/9/2016  Bronze
             l        Heritag                                sponsor
             Allian   e Lane,                                2016 NAMI
             ce for   Suite                                  California
             the      150                                    Annual
             Mental   Sacrame                                Conference
             ly Ill   nto, CA
                      95815
------------------------------------------------------------------------
Monetary    Nationa  The               $1,000    3/15/2016  Bronze
             l        Schraff                                sponsor
             Allian   t's                                    NAMIWalks
             ce for   Center                                 Mass--May
             the      529                                    14, 2016
             Mental   Main
             ly Ill   Street,
                      Suite
                      1M17
                      Boston,
                      MA
                      02129
------------------------------------------------------------------------
Monetary    Nationa  3250              $1,000    3/15/2016  Bronze
             l        Wilshir                                sponsor
             Allian   e                                      NAMIWalks
             ce for   Blvd.,                                 Los Angeles
             the      Suite                                  County--Oct
             Mental   1501                                   ober 1,
             ly Ill   Los                                    2016
                      Angeles
                      , CA
                      90010
------------------------------------------------------------------------
Monetary    Nationa  2812              $1,000    5/16/2016  Bronze
             l        Swiss                                  sponsor
             Allian   Avenue                                 Dallas
             ce for   Dallas,                                NAMIWalk--M
             the      TX                                     ay 14, 2016
             Mental   75204
             ly Ill
------------------------------------------------------------------------
Monetary    Nationa  1706              $1,000    3/15/2016  Bronze
             l        Brady                                  sponsor
             Allian   Street                                 NAMIWalks
             ce for   Suite                                  Greater
             the      101                                    Mississippi
             Mental   Davenpo                                Valley--Sep
             ly Ill   rt, IA                                 tember 24,
                      52803                                  2016
------------------------------------------------------------------------
Monetary    Nationa  PO Box            $1,000     8/4/2016  NAMIFest
             l        4096                                   2016--2 Day
             Allian   Alvin,                                 Educational
             ce for   TX                                     Conference
             the      77512
             Mental
             ly Ill
------------------------------------------------------------------------
Monetary    Nationa  1225              $7,500     2/9/2016  The Year of
             l        Dublin                                 the
             Allian   Road,                                  Affiliate:
             ce for   Suite                                  Strengtheni
             the      125                                    ng NAMI's
             Mental   Columbu                                Voice in
             ly Ill   s, OH                                  Ohio's
                      43215                                  Local
                                                             Communities
------------------------------------------------------------------------
Monetary    Nationa  1562              $1,000     2/2/2016  Bronze
             l        Route                                  sponsor
             Allian   130                                    2016 NAMI
             ce for   North                                  Walks New
             the      Brunswi                                Jersey,
             Mental   ck, NJ                                 ``Step
             ly Ill   08902                                  Forward for
                                                             Our
                                                             Heroes''
------------------------------------------------------------------------
Monetary    Nationa  5095              $1,000     2/2/2016  Bronze
             l        Murphy                                 sponsor
             Allian   Canyon                                 2016 NAMI
             ce for   Road                                   Walk
             the      Suite
             Mental   320 San
             ly Ill   Diego,
                      CA
                      92123
------------------------------------------------------------------------
Monetary    Nationa  3200 S.           $1,000     2/9/2016  Bronze
             l        3rd                                    sponsor
             Allian   Street,                                2016
             ce for   Unit 6                                 NAMIWalks
             the      Milwauk                                Greater
             Mental   ee, WI                                 Milwaukee
             ly Ill   53207
------------------------------------------------------------------------
Monetary    Nationa  2601              $2,500     2/9/2016  Supporting
             l        Cold                                   sponsor
             Allian   Spring                                 NAMI
             ce for   Road                                   Indiana's
             the      P.O.                                   13th Annual
             Mental   Box                                    Mental
             ly Ill   22697                                  Health and
                      Indiana                                Criminal
                      polis,                                 Justice
                      IN                                     Summit
                      46222
------------------------------------------------------------------------
Monetary    Nationa  576               $1,500     2/9/2016  Bronze
             l        Farming                                sponsor
             Allian   ton                                    2016 NAMI
             ce for   Avenue                                 Walk
             the      Hartfor
             Mental   d, CT
             ly Ill   06105
------------------------------------------------------------------------
Monetary    Nationa  PO Box            $1,000    5/27/2016  Platinum
             l        550039                                 sponsor
             Allian   Birming                                2016 NAMI
             ce for   ham, AL                                Birmingham
             the      35255-                                 Walk for
             Mental   0039                                   Mental
             ly Ill                                          Health--9/
                                                             17/16
------------------------------------------------------------------------
Monetary    Nationa  1536              $8,000    6/24/2016  Honest,
             l        West                                   Open, Proud
             Allian   Chicago                                to erase
             ce for   Ave                                    the stigma
             the      Chicago                                of mental
             Mental   , IL                                   illness
             ly Ill   60642
------------------------------------------------------------------------
Monetary    Nationa  1562              $2,500   11/18/2016  2016 NAMI NJ
             l        Route                                  Conference:
             Allian   130                                    ``Building
             ce for   North                                  Better
             the      Brunswi                                Lives''
             Mental   ck, NJ
             ly Ill   08902
------------------------------------------------------------------------
Monetary    Nationa  3333              $1,000   12/14/2016  Pink Ribbon
             l        West                                   Sponsor--20
             Allian   Pensaco                                17
             ce for   la                                     Blueberry
             the      Street                                 Horseshoe
             Mental   Suite                                  5k--Februar
             ly Ill   250                                    y 19, 2017
                      Tallaha
                      ssee,
                      FL
                      32302-0
                      961
------------------------------------------------------------------------
Monetary    Nationa  99 Pine           $4,000    12/1/2016  2016 NAMI-
             l        St.                                    NYS
             Allian   Suite                                  Education
             ce for   302                                    Conference
             the      Albany,
             Mental   NY
             ly Ill   12207
------------------------------------------------------------------------
Monetary    Nationa  3803 N.          $75,000   12/15/2016  Strengthenin
             l        Fairfax                                g CIT
             Allian   Drive
             ce for   Suite
             the      100
             Mental   Arlingt
             ly Ill   on, VA
                      22203
------------------------------------------------------------------------
Monetary    Nationa  3803 N.          $50,000   12/15/2016  NAMI
             l        Fairfax                                Helpline
             Allian   Drive
             ce for   Suite
             the      100
             Mental   Arlingt
             ly Ill   on, VA
                      22203
------------------------------------------------------------------------
Monetary    Nationa  2012              $5,000    6/24/2016  Mental
             l        West                                   Illness
             Allian   25th                                   Education
             ce for   Street,
             the      #600
             Mental   Clevela
             ly       nd, OH
             Ill--G   44113
             reater
             Clevel
             and
------------------------------------------------------------------------
Monetary    Nationa  2012              $1,000    3/15/2016  Bronze
             l        West                                   sponsor
             Allian   25th                                   NAMIWalks--
             ce for   Street,                                August 27,
             the      #600                                   2016
             Mental   Clevela
             ly       nd, OH
             Ill--G   44113
             reater
             Clevel
             and
------------------------------------------------------------------------
Monetary    Nationa  3839              $1,000    3/15/2016  Bronze
             l        Merle                                  sponsor
             Allian   Hay                                    NAMIWalks
             ce for   Road,                                  Iowa--Septe
             the      Suite                                  mber 24,
             Mental   226 Des                                2016
             ly       Moines,
             Ill--I   IA
             owa      50310
------------------------------------------------------------------------
Monetary    Nationa  505 8th           $1,000    3/15/2016  Bronze
             l        Avenue,                                sponsor
             Allian   Ste                                    NAMIWalks
             ce for   1103                                   NYC--May 7,
             the      New                                    2016
             Mental   York,
             ly Ill   NY
             of New   10018
             York
             City
------------------------------------------------------------------------
Monetary    Nationa  1981              $1,000   11/11/2016  Bronze
             l        Marcus                                 sponsor
             Allian   Ave                                    NAMIWalks
             ce for   Suite                                  Long Island/
             the      C117                                   Queens May
             Mental   Lake                                   6, 2017
             ly Ill   Success
             Queens/  , NY
             Nassau   11042
------------------------------------------------------------------------
Monetary    Nationa  5963              $1,000    7/20/2016  Bronze
             l        Boymel                                 sponsor
             Allian   Dr.                                    NAMIWalks
             ce on    Fairfie                                Butler
             Mental   ld, OH                                 County--Oct
             Illnes   45014                                  ober 8,
             s                                               2016
------------------------------------------------------------------------
Monetary    Nationa  324A              $1,000    3/15/2016  NAMI Walk--
             l        Springf                                May 15,
             Allian   ield                                   2016
             ce on    Street
             Mental   Agawam,
             Illnes   MA
             s        01001
             Wester
             n
             Mass.,
             Inc.
------------------------------------------------------------------------
Monetary    Nationa  P O Box           $6,000     5/3/2016  29th Annual
             l Art    350891                                 NAEMI Art
             Exhibi   Miami,                                 Exhibition
             tions    FL
             of the   33135
             Mental
             ly
             Ill,
             Inc.
------------------------------------------------------------------------
Monetary    Nationa  1400 K           $75,000   12/15/2016  Policy
             l        St NW,                                 Action
             Counci   #400                                   Center
             l for    Washing
             Behavi   ton, DC
             oral     20005
             Health
------------------------------------------------------------------------
Monetary    Nationa  1400 K           $75,000   12/15/2016  Early Onset
             l        St NW,                                 Psychosis
             Counci   #400                                   Community
             l for    Washing                                of Practice
             Behavi   ton, DC
             oral     20005
             Health
------------------------------------------------------------------------
Monetary    Nationa  1400 K           $75,000   12/15/2016  Health
             l        St NW,                                 Justice
             Counci   #400                                   Learning
             l for    Washing                                Collaborati
             Behavi   ton, DC                                ve
             oral     20005
             Health
------------------------------------------------------------------------
Monetary    Nationa  949 W.            $7,500   12/15/2016  Academic
             l        State                                  Creative
             Junior   Street                                 Engagement
             Tennis   Trenton                                (ACE)
             and      , NJ                                   Program and
             Learni   08618                                  Science
             ng of                                           Technology
             Trento                                          Engineering
             n                                               Arts Math
                                                             (STEAM)
                                                             Pilot
                                                             Program
------------------------------------------------------------------------
Monetary    Nationa  9707 E           $20,000   12/22/2016  Stroke
             l        Easter                                 Recovery
             Stroke   Lane,                                  Navigator
             Associ   Suite B
             ation    Centenn
                      ial, CO
                      80112
------------------------------------------------------------------------
Monetary    Nationa  9707 E           $30,000   12/22/2016  National
             l        Easter                                 Stroke
             Stroke   Lane,                                  Awareness
             Associ   Suite B                                Month
             ation    Centenn
                      ial, CO
                      80112
------------------------------------------------------------------------
Monetary    New      275 Rt.           $4,000    4/12/2016  NJPC NJ
             Jersey   10 East                                Youth
             Parent   Suite                                  Caucus
             s        220-414                                (Formerly
             Caucus   Succasu                                known as NJ
                      nna, NJ                                Youth
                      07876                                  Coalition)
------------------------------------------------------------------------
Monetary    NewBrid  7                 $2,000    6/24/2016  NewBridge
             ge       Industr                                Day
             Servic   ial                                    Treatment
             es,      Road                                   Progam for
             Inc.     P.O.                                   Adults
                      Box 336
                      Pequann
                      ock, NJ
                      07440
------------------------------------------------------------------------
Monetary    Northea  2900              $2,500    7/12/2016  Day of
             st       Conner                                 Restoration
             Guidan   Avenue,                                -assistance
             ce       Buildin                                for
             Center   g A                                    Detroit's
                      Detroit                                Homeless
                      , MI                                   with Mental
                      48215                                  Illness
------------------------------------------------------------------------
Monetary    NorthSh  1033             $10,000   12/22/2016  Clot Aware
             ore      Univers                                Support
             Univer   ity                                    Group
             sity     Place
             Health   Suite
             system   450
                      Evansto
                      n, IL
                      60201
------------------------------------------------------------------------
Monetary    Ohio     33 N.             $2,500    3/21/2016  Ohio's 2016
             Associ   High                                   Recovery
             ation    Street,                                Conference:
             of       Ste.                                   Recovery Is
             County   500                                    Beautiful
             Behavi   Columbu
             oral     s, OH
             Health   43215
             Author
             ities
------------------------------------------------------------------------
Monetary    Pancrea  1500                $100    2/15/2016  Memorial
             tic      Rosecra                                Donation
             Cancer   ns Ave,
             Action   Suite
             Networ   200
             k        Manhatt
                      an
                      Beach,
                      CA
                      90266
------------------------------------------------------------------------
Monetary    Passage  PO Box            $7,500   12/15/2016  Support for
             Theatr   967                                    the State
             e        Trenton                                Street
             Compan   , NJ                                   Project
             y Inc.   08605
------------------------------------------------------------------------
Monetary    PEI      231              $17,500   10/26/2016  Comprehensiv
             Kids     Lawrenc                                e Juvenile
                      e Road                                 Offenders
                      Lawrenc                                Outreach
                      eville,                                Services
                      NJ
                      08648
------------------------------------------------------------------------
Monetary    PEI      231                 $300   10/20/2016  Costs
             Kids     Lawrenc                                associated
                      e Road                                 with 2016
                      Lawrenc                                Janssen
                      eville,                                Cares event
                      NJ
                      08648
------------------------------------------------------------------------
Monetary    People   295               $2,500   11/18/2016  Reading
             And      Eggerts                                Deeply in
             Storie   Crossin                                Community:
             s--Gen   g Road                                 A
             te Y     Lawrenc                                Literature
             Cuento   eville,                                Project for
             s Inc.   NJ                                     Mercer
                      08648                                  County
                                                             Youth and
                                                             Seniors
------------------------------------------------------------------------
Monetary    Places   4130                $100     3/3/2016  Memorial
             for      Lindell                                Donation
             People   Blvd.
             , Inc.   St.
                      Louis,
                      MO
                      63108
------------------------------------------------------------------------
Monetary    Planned  P.O. Box          $5,000    4/12/2016  Life
             Living   4755                                   Planning
             Assist   Austin,                                Program
             ance     TX
             Networ   78765
             k of
             Centra
             l
             Texas
------------------------------------------------------------------------
Monetary    Positiv  1411 N.              $75     3/1/2016  Donation in
             e        Westsho                                lieu of
             Coachi   re                                     company
             ng       Blvd.                                  holiday
             Allian   Suite                                  gift
             ce       205
                      Tampa
                      Bay, FL
                      33607
------------------------------------------------------------------------
Monetary    Princet  15               $50,000   12/21/2016  Bridge to
             on       Princes                                Employment
             Area     s Road                                 program
             Commun   Lawrenc
             ity      eville,
             Founda   NJ
             tion,    08648
             Inc.
------------------------------------------------------------------------
Monetary    Princet  P.O. Box          $2,500   12/15/2016  PGC
             on       145 190                                Afterschool
             Girl     Nassau                                 Music
             Choir    Street,                                Outreach
                      Lower                                  Program
                      Level
                      Princet
                      on, NJ
                      08542
------------------------------------------------------------------------
Monetary    Princet  123 E.           $10,000   12/15/2016  Hunger
             on       Hanover                                Prevention
             Outrea   St.                                    and
             ch       Trenton                                Nutrition
             Projec   , NJ                                   Education
             ts /     08608                                  ($7,500.00)
             Crisis                                          Healthy
             Minist                                          Living and
             ry of                                           Housing
             Mercer                                          Stability
             County                                          Services
                                                             ($2,500.00)
------------------------------------------------------------------------
Monetary    Princet  45                $4,000   12/15/2016  Family
             on       Stockto                                Caregiver
             Senior   n St                                   Conference:
             Resour   Princet                                Family
             ce       on, NJ                                 Caregiving:
             Center   08540                                  Compassion
                                                             for Self
                                                             and Others
------------------------------------------------------------------------
Monetary    Princet  575               $3,500   12/15/2016  BRAVO!
             on       Ewing                                  Trenton
             Sympho   Street                                 Initiative
             ny       Princet
             Orches   on, NJ
             tra      08540
------------------------------------------------------------------------
Monetary    Princet  13                $7,500   12/15/2016  Summer
             on-      Roszel                                 Bridge
             Blairs   Road,                                  2017--Trent
             town     Suite                                  on
             Center   C204A
             Inc.     Princet
                      on, NJ
                      08540
------------------------------------------------------------------------
Monetary    Printma  440               $5,000   12/22/2016  Roving Press
             king     River
             Center   Road
             of New   Branchb
             Jersey   urg, NJ
                      08876
------------------------------------------------------------------------
Monetary    Printma  440              $15,000    12/8/2016  Combat Paper
             king     River                                  NJ
             Center   Road
             of New   Branchb
             Jersey   urg, NJ
                      08876
------------------------------------------------------------------------
Monetary    Raritan  P. O.             $7,000   12/15/2016  WaterWays
             Headwa   Box 273                                Environment
             ters     Gladsto                                al
             Associ   ne, NJ                                 Education
             ation    07934                                  Program
------------------------------------------------------------------------
Monetary    Raritan  118              $20,000   10/24/2016  Promoting
             Valley   Lamingt                                Access to
             Commun   on Rd                                  STEM and
             ity      Branchb                                Nursing
             Colleg   urg, NJ                                Education
             e        08844                                  at Raritan
                                                             Valley
                                                             Community
                                                             College
------------------------------------------------------------------------
Monetary    Recover  3423             $15,000    5/16/2016  Healthy
             y        Covingt                                Start Pilot
             Consul   on                                     Program--(M
             tants    Drive,                                 ental
             Of       Suite B                                Health
             Atlant   Decatur                                Portion of
             a        , GA                                   Program)
             Incorp   30032
             orated
------------------------------------------------------------------------
Monetary    Regions  640              $15,000    5/16/2016  Make It OK,
             Hospit   Jackson                                the
             al       Street,                                campaign to
             Founda   MS                                     fight
             tion     11202C                                 stigma
                      St.
                      Paul,
                      MN
                      55101
------------------------------------------------------------------------
Monetary    Rescue   98               $25,000   12/16/2016  Emergency
             Missio   Carroll                                Services
             n of     St. PO                                 program
             Trento   Box 790
             n        Trenton
                      , NJ
                      08605
------------------------------------------------------------------------
Monetary    Rider    2083             $19,500    12/6/2016  Summer STEM
             Univer   Lawrenc                                ($12,000);
             sity     eville                                 Scholarship
                      Road                                   Support
                      Lawrenc                                ($5,000);
                      eville,                                Shakesperia
                      NJ                                     n at Rider
                      08648                                  ($2,500)
------------------------------------------------------------------------
Monetary    Riverbe  PO Box            $5,000    4/12/2016  InSHAPE
             nd       2032                                   Program
             Commun   Concord
             ity      , NH
             Mental   03302-
             Health   2032
             Inc.
------------------------------------------------------------------------
Monetary    Riversi  4 South          $10,000    12/7/2016  Riverside
             de       Union                                  Symphonia
             Sympho   Street                                 Senior
             nia      P.O.                                   Outreach
             Inc.     Box 650                                Program
                      Lambert
                      ville,
                      NJ
                      08530
------------------------------------------------------------------------
Monetary    Rutgers  4               $124,863    9/19/2016  Corporate
             Univer   Hunting                                Social
             sity     ton                                    Responsibil
             School   Street                                 ity
             of       New                                    Fellowship
             Commun   Brunswi
             icatio   ck, NJ
             n,       08901-
             Inform   1071
             ation
             and
             Librar
             y
             Studie
             s
------------------------------------------------------------------------
Monetary    SAFE in  47 East             $600    9/22/2016  Costs
             Hunter   Main                                   associated
             don      Street                                 with 2016
                      Fleming                                Janssen
                      ton, NJ                                Cares
                      08822                                  Volunteer
                                                             Activity
------------------------------------------------------------------------
Monetary    Saint    436 Port            $100    3/28/2016  Memorial
             Anthon   Reading                                Donation
             y of     Avenue
             Padua    Port
             Roman    Reading
             Cathol   , NJ
             ic       07064
             Church
------------------------------------------------------------------------
Monetary    San      2789-             $5,000    5/16/2016  MHRC Client
             Franci   25th                                   Wellness
             sco      Street,                                Enhancement
             Genera   #2028                                  Project
             l        San
             Hospit   Francis
             al       co, CA
             Founda   94110
             tion
------------------------------------------------------------------------
Monetary    SAVE A   1010                $600    9/19/2016  Costs
             Friend   Route                                  associated
             to       601                                    with 2016
             Homele   Cedar                                  Janssen
             ss       Lodge                                  Cares
             Animal   Road                                   Volunteer
             s        Skillma                                Activity
                      n, NJ
                      08558
------------------------------------------------------------------------
Monetary    Schizop  602 Pink          $5,000    5/23/2016  Platinum
             hrenia   Azalea                                 sponsor
             and      Trl PO                                 2016
             Relate   Box                                    symposium
             d        941222                                 and
             Disord   Houston                                workshop,
             ers      , TX                                   ``You are
             Allian   77094-                                 NOT Alone''
             ce Of    8222                                   Self-help/
             Americ                                          peer
             a                                               support
                                                             Symposium
                                                             and
                                                             workshop
------------------------------------------------------------------------
Monetary    Scripps  10140            $25,000   12/14/2016  Scripps
             Founda   Campus                                 Community
             tion     Point                                  Diabetes
             for      Drive                                  Programs:
             Medici   Suite                                  Dulce
             ne and   200 San                                Transitions
             Scienc   Diego,
             e        CA
                      92121
------------------------------------------------------------------------
Monetary    Scripps  10140            $30,000   12/14/2016  Scripps
             Founda   Campus                                 Community
             tion     Point                                  Diabetes
             for      Drive                                  and
             Medici   Suite                                  Prevention
             ne and   200 San                                Programs:
             Scienc   Diego,                                 Project
             e        CA                                     Dulce
                      92121
------------------------------------------------------------------------
Monetary    SERV     20                $5,000    9/15/2016  14th Annual
             Founda   Scotch                                 SERV
             tion,    Road,                                  Wellness
             Inc.     3rd                                    and
                      Floor                                  Development
                      Ewing,                                 Conference
                      NJ
                      08628
------------------------------------------------------------------------
Monetary    SERV     20                $7,500    9/15/2016  SERV
             Founda   Scotch                                 Foundation
             tion,    Road,                                  Scholarship
             Inc.     3rd                                    Fund
                      Floor
                      Ewing,
                      NJ
                      08628
------------------------------------------------------------------------
Monetary    Shannon  PO Box              $500   12/14/2016  Shannon
             Daley    1271 36                                Daley
             Memori   Indian                                 Memorial
             al       Run                                    Fund
             Fund     Whiteho                                Charity
                      use                                    Events
                      Station
                      , NJ
                      08889
------------------------------------------------------------------------
Monetary    Sharing  1920              $2,000    5/30/2016  1920 Club
             Place    10th                                   Art Program
             Inc.     Avenue
                      South
                      PO Box
                      59455
                      Birming
                      ham, AL
                      35255
------------------------------------------------------------------------
Monetary    Shiloh   PO Box            $5,000    2/18/2016  Family
             Commun   398                                    Wellness
             ity      Trenton                                Club--Diabe
             Develo   , NJ                                   tes and
             pment    08603                                  Chronic
             Corpor                                          Disease
             ation                                           Self
                                                             Management
------------------------------------------------------------------------
Monetary    Shiloh   PO Box            $5,000   12/15/2016  Family
             Commun   398                                    Wellness
             ity      Trenton                                Club--Diabe
             Develo   , NJ                                   tes and
             pment    08603                                  Chronic
             Corpor                                          Disease
             ation                                           Self
                                                             Management
------------------------------------------------------------------------
Monetary    Sister   1201              $5,000    9/14/2016  Pearl Grace
             Networ   Hamilto                                Breast
             k of     n                                      Cancer
             Centra   Street                                 Assistant
             l New    Somerse                                Tournament
             Jersey   t, NJ
             , Inc.   08873
------------------------------------------------------------------------
Monetary    Somerse  49                $7,500   12/23/2016  Street
             t Home   Brahma                                 Smart--HIV/
             for      Avenue                                 AIDS
             Tempor   P.O.                                   Program
             arily    Box
             Displa   6871
             ced      Bridgew
             Childr   ater,
             en       NJ
                      08807
------------------------------------------------------------------------
Monetary    Somerse  49                  $900    12/5/2016  Costs
             t Home   Brahma                                 associated
             for      Avenue                                 with 2016
             Tempor   P.O.                                   Janssen
             arily    Box                                    Cares
             Displa   6871                                   Volunteer
             ced      Bridgew                                Activity
             Childr   ater,
             en       NJ
                      08807
------------------------------------------------------------------------
Monetary    Somerse  One              $20,000   12/13/2016  El Poder
             t        Rehill                                 Sobre La
             Medica   Avenue                                 Diabetes--N
             l        Somervi                                J Neighbor
             Center   lle, NJ                                of Choice
             Founda   08876                                  Program
             tion
------------------------------------------------------------------------
Monetary    Somervi  51 West           $2,000   10/19/2016  A Maker
             lle      Cliff                                  Space for
             Educat   Street                                 Every Child
             ional    P.O.
             Founda   Box
             tion,    8721
             Inc.     Somervi
                      lle, NJ
                      08876
------------------------------------------------------------------------
Monetary    St.      1025                $100     3/3/2016  Memorial
             Mark     Radclif                                Donation
             Church   fe
             and      Street
             School   Bristol
                      , PA
                      19007
------------------------------------------------------------------------
Monetary    St.      One              $15,000   12/21/2016  Providing
             Mary     Summit                                 Food for
             Medica   Square,                                Underserved
             l        Suite                                  School-Age
             Center   300                                    Children in
             Founda   1717                                   Bucks
             tion     Langhor                                County: The
                      ne-                                    St. Mary
                      Newtown                                Backpacks
                      Road                                   for Kids
                      Langhor                                Program
                      ne, PA
                      19047
------------------------------------------------------------------------
Monetary    Stony    31 Titus         $15,000   10/26/2016  StreamWatch
             Brook    Mill                                   Volunteer
             Millst   Road                                   Water
             one      Penning                                Quality
             Waters   ton, NJ                                Monitoring
             hed      08534                                  Program
             Associ
             ation
------------------------------------------------------------------------
Monetary    T-1      8216             $35,000   10/25/2016  Friends for
             Today    Princet                                Life
             Inc.     on-                                    Orlando
                      Glendal                                2017
                      e Road,
                      PMB 200
                      West
                      Chester
                      , OH
                      45069
------------------------------------------------------------------------
Monetary    Taking   1110             $35,000   10/25/2016  Taking
             Contro   Camino                                 Control Of
             l of     Del Mar                                Your
             Your     Suite C                                Diabetes
             Diabet   Del                                    (TCOYD)
             es       Mar, CA                                Conference
                      92014                                  and Health
                                                             Fair
------------------------------------------------------------------------
Monetary    TASK,    72\1/2\          $25,000   10/26/2016  Trenton Area
             Inc.     Escher                                 Soup
                      Street,                                Kitchen
                      P.O.                                   Meal
                      Box 872                                Service
                      Trenton                                Program
                      , NJ
                      08605
------------------------------------------------------------------------
Monetary    The      Paul              $5,000    9/15/2016  Communiversi
             Arts     Robeson                                ty ArtsFest
             Counci   Center                                 2017
             l of     for the
             Prince   Arts
             ton      102
                      Withers
                      poon
                      Street
                      Princet
                      on, NJ
                      08542
------------------------------------------------------------------------
Monetary    The      Paul             $10,000    9/15/2016  Arts Council
             Arts     Robeson                                of
             Counci   Center                                 Princeton
             l of     for the                                Community
             Prince   Arts                                   Outreach
             ton      102                                    Programs
                      Withers
                      poon
                      Street
                      Princet
                      on, NJ
                      08542
------------------------------------------------------------------------
Monetary    The      2020              $2,000   12/23/2016  Art Classes
             Center   Burnt                                  for
             for      Mills                                  Children
             Contem   Road                                   with Autism
             porary   Bedmins                                Spectrum
             Art      ter, NJ                                Disorder
                      07921                                  and Other
                                                             Special
                                                             Needs
------------------------------------------------------------------------
Monetary    The      19               $12,000    9/14/2016  Support of
             Center   Dellwoo                                Adult
             For      d Lane                                 Women's
             Great    Somerse                                Program
             Expect   t, NJ                                  through a
             ations   08873                                  Program
                                                             Grant and
                                                             2016 Gift
                                                             of Hope
                                                             Gala
                                                             Sponsorship
------------------------------------------------------------------------
Monetary    The      1040              $7,500     8/4/2016  Jail
             Edinbu   Waltham                                Diversion
             rg       Street                                 Program
             Center   Lexingt
                      on, MA
                      02421
------------------------------------------------------------------------
Monetary    The      222              $75,000   12/22/2016  Terracotta
             Frankl   North                                  Warriors:
             in       20th                                   Guards for
             Instit   St.                                    Eternity
             ute      Philade
                      lphia,
                      PA
                      19103
------------------------------------------------------------------------
Monetary    The      1289                $300    9/22/2016  Costs
             Legacy   Route                                  associated
             Treatm   38 West                                with 2016
             ent      Suite                                  Janssen
             Servic   203                                    Cares
             es       Hainesp                                Volunteer
             Founda   ort, NJ                                Activity
             tion     08036
------------------------------------------------------------------------
Monetary    The      8150 N.          $40,000   12/14/2016  HeartGuide--
             Mended   Central                                Patient
             Hearts   Express                                Resource
             , Inc.   way                                    and
                      Suite                                  Visiting
                      M2248                                  Program: An
                      Dallas,                                Educational
                      TX                                     and Support
                      75206                                  Program for
                                                             Patients,
                                                             Caregivers
                                                             and
                                                             Families
                                                             Affected by
                                                             Heart
                                                             Disease
------------------------------------------------------------------------
Monetary    The      401               $1,000    4/11/2016  Head Lite
             Mental   Cypress                                sponsor 7th
             Health   Street                                 Annual Lite
             Center   Manches                                up the Nite
             Of       ter, NH                                Run/Walk
             Greate   03103                                  for Mental
             r                                               Health--Jun
             Manche                                          e 23, 2016
             ster
------------------------------------------------------------------------
Monetary    The      P.O. Box          $7,500   11/18/2016  Opera for
             Prince   2063                                   All
             ton      Princet
             Festiv   on, NJ
             al       08543
------------------------------------------------------------------------
Monetary    The      4101             $20,000    8/23/2016  MindStrong
             Thresh   North                                  program
             olds     Ravensw
                      ood
                      Avenue
                      Chicago
                      , IL
                      60613
------------------------------------------------------------------------
Monetary    The      100              $10,000     8/4/2016  Farm Based
             Willia   Gould                                  Psychiatric
             m J.     Road PO                                Rehabilitat
             Gould    Box 157                                ion and
             Associ   Montere                                Recovery
             ates,    y, MA
             Inc.     01245
------------------------------------------------------------------------
Monetary    Thomas   111 West         $12,000   12/15/2016  Scholarship
             Edison   State                                  Support for
             State    Street                                 Nursing
             Colleg   Trenton                                Students
             e        , NJ                                   Enrolled in
             Founda   08608                                  the W. Cary
             tion                                            Edwards
                                                             School of
                                                             Nursing's
                                                             Accelerated
                                                             Second
                                                             Degree BSN
                                                             Program at
                                                             Thomas
                                                             Edison
                                                             State
                                                             University
------------------------------------------------------------------------
Monetary    Tpto     51 South          $1,000    9/12/2016  2017
             Inc.--   Timberl                                Timberlane
             Timber   ane                                    Science and
             lane     Drive,                                 Engineering
             Parent   Penning                                Fair
             Teache   ton, NJ
             r        08534
             Organi
             zation
------------------------------------------------------------------------
Monetary    Trenton  439 S.            $7,000    9/12/2016  Second
             Commun   Broad                                  Semester,
             ity      Street,                                Trenton
             Music    Ste. 90                                Community
             School   Trenton                                Music
                      , NJ                                   School
                      08638
------------------------------------------------------------------------
Monetary    Trenton  635               $5,000   12/15/2016  Trenton
             Educat   South                                  Education
             ion      Clinton                                Dance
             Dance    Avenue                                 Institute
             Instit   Trenton                                (TEDI)
             ute      , NJ
                      08611
------------------------------------------------------------------------
Monetary    Trenton  218 N            $15,000   11/22/2016  Navigating
             Health   Broad                                  for Health
             Team     St
             Inc.     Trenton
                      , NJ
                      08608
------------------------------------------------------------------------
Monetary    Trinity  22                $7,500   12/15/2016  TCS Mental
             Counse   Stockto                                Health and
             ling     n                                      Wellness
             Servic   Street                                 Program
             es       Trinity
                      Counsel
                      ing
                      Service
                      Princet
                      on, NJ
                      08540
------------------------------------------------------------------------
Monetary    Tuscalo  PO Box            $1,000    3/30/2016  Supporting
             osa      2322                                   sponsorship
             Mental   Tuscalo                                -Hot
             Health   osa, AL                                Hundred
             Allian   35403                                  Bicycle
             ce                                              Ride--July,
                                                             30, 2016
------------------------------------------------------------------------
Monetary    Twiligh  P.O. Box          $7,500    11/9/2016  Simple Needs
             t Wish   1042 11                                Wish
             Founda   Duane                                  Granting
             tion     Road                                   Program
                      Doylest
                      own, PA
                      18901
------------------------------------------------------------------------
Monetary    UIH      4 North           $9,000   12/15/2016  Community of
             Family   Broad                                  Health for
             Partne   Street                                 Men, Year 3
             rs       2nd
                      Floor
                      Trenton
                      , NJ
                      08618-
                      4408
------------------------------------------------------------------------
Monetary    United   9-25              $7,500   11/18/2016  Janssen
             Negro    Alling                                 Pharmaceuti
             Colleg   Street                                 cals-
             e Fund   2nd                                    Princeton
                      Floor                                  Committee
                      Newark,                                of UNCF
                      NJ                                     Scholarship
                      07102
------------------------------------------------------------------------
Monetary    United   Crossroa        $530,664   12/19/2016  Company
             Way of   ds                                     match to
             Greate   Corpora                                employee
             r        te                                     United Way
             Mercer   Center                                 campaign
             County   3150                                   for
                      Brunswi                                Titusville
                      ck                                     based
                      Pike,                                  companies
                      Suite
                      230
                      Lawrenc
                      eville,
                      NJ
                      08648-
                      2420
------------------------------------------------------------------------
Monetary    United   4 Walter            $600   11/29/2016  Costs
             Way of   Foran                                  associated
             Hunter   Blvd.                                  with 2016
             don      Fleming                                Janssen
             County   ton, NJ                                Cares
                      08822                                  Volunteer
                                                             Activity
------------------------------------------------------------------------
Monetary    United   PO Box           $42,219   12/21/2016  Company
             Way of   6835                                   match to
             Northe   1011                                   employee
             rn New   Route                                  United Way
             Jersey   22                                     campaign
                      West,                                  less Truist
                      2nd                                    processing
                      Floor                                  fee for
                      Bridgew                                Raritan
                      ater,                                  campus
                      NJ
                      08807
------------------------------------------------------------------------
Monetary    Urbanpr  801 West          $3,500   10/26/2016  StreetLeader
             omise    State                                  Program
             Intern   Street
             ationa   Trenton
             l Inc.   , NJ
                      08618
------------------------------------------------------------------------
Monetary    Valeo    5401 SW           $3,500    4/12/2016  Creations of
             Behavi   7th                                    Hope: A
             oral     Street                                 gallery by
             Health   Topeka,                                artists
             Care     KS                                     experiencin
             Inc.     66606                                  g mental
                                                             illness
                                                             focused on
                                                             advocacy
                                                             through
                                                             art.
------------------------------------------------------------------------
Monetary    Volunte  12                $7,500   12/15/2016  SkillsConnec
             er       Stockto                                t
             Connec   n
             t        Street
                      Princet
                      on, NJ
                      08540
------------------------------------------------------------------------
Monetary    Washing  P. O.               $750    9/12/2016  Educational
             ton      Box 83                                 program
             Crossi   Titusvi                                support:
             ng       lle, NJ                                ``Digging
             Park     08560                                  New Jersey:
             Associ                                          Colonial
             ation                                           and
             Inc.                                            Revolutiona
                                                             ry War
                                                             Archeology'
                                                             ' and ``The
                                                             Occupation
                                                             of Trenton:
                                                             December 1-
                                                             21, 1776''
------------------------------------------------------------------------
Monetary    West     PO Box            $5,000    11/9/2016  Excellence
             Windso   280                                    in
             r        West                                   Education
             Plains   Windsor                                Grant
             boro     , NJ                                   Program
             Educat   08550-
             ion      0280
             Founda
             tion
------------------------------------------------------------------------
Monetary    Womansp  1530              $5,000   11/18/2016  Domestic
             ace      Brunswi                                Violence
                      ck Ave.                                Shelter
                      Lawrenc                                (Safe
                      eville,                                House) and
                      NJ                                     Transitiona
                      08648                                  l Housing
                                                             (Barbara's
                                                             House)
------------------------------------------------------------------------
Monetary    Women's  3200                 $75    1/19/2016  Employee
             Commun   Hilltop                                directed
             ity,     Avenue                                 donation in
             Inc.     Wausau,                                lieu of
                      WI                                     company
                      54401                                  holiday
                                                             gift
------------------------------------------------------------------------
Monetary    Woods    40                  $600   10/24/2016  2016 Janssen
             Servic   Martin                                 Cares
             es       Gross                                  Volunteer
             Founda   Drive                                  Events
             tion     PO box
                      36
                      Langhor
                      ne, PA
                      19047
------------------------------------------------------------------------
Monetary    Woods    40                $4,000   12/15/2016  Yoga at
             Servic   Martin                                 Maplewood:
             es       Gross                                  A Program
             Founda   Drive                                  for People
             tion     PO box                                 with Prader-
                      36                                     Willi
                      Langhor                                Syndrome
                      ne, PA
                      19047
------------------------------------------------------------------------
Product     AmeriCa  88           $ 1,489,699    4/27/2016  Product
             res      Hamilto                                donation
             Founda   n Ave                                  for
             tion     Stamfor                                humanitaria
                      d, CT                                  n
                      06902                                  assistance
                                                             in Gaza,
                                                             Tanzania,
                                                             West Bank,
                                                             Afghanistan
                                                             , USA,
                                                             Jamaica,
                                                             Nicaragua
------------------------------------------------------------------------
Product     AmeriCa  88           $ 1,865,102    4/27/2016  Product
             res      Hamilto                                donation
             Founda   n Ave                                  for
             tion     Stamfor                                humanitaria
                      d, CT                                  n
                      06902                                  assistance
                                                             in
                                                             Afghanistan
                                                             , Jamaica,
                                                             Nicaragua,
                                                             USA
------------------------------------------------------------------------
Product     AmeriCa  88           $ 2,283,779    4/27/2016  Product
             res      Hamilto                                donation
             Founda   n Ave                                  for
             tion     Stamfor                                humanitaria
                      d, CT                                  n
                      06902                                  assistance
                                                             in
                                                             Afghanistan
                                                             , Armenia,
                                                             Nicaragua,
                                                             Peru, St.
                                                             Lucia, West
                                                             Bank
------------------------------------------------------------------------
Product     AmeriCa  88             $ 189,778    4/27/2016  Product
             res      Hamilto                                donation
             Founda   n Ave                                  for
             tion     Stamfor                                humanitaria
                      d, CT                                  n
                      06902                                  assistance
                                                             in USA
------------------------------------------------------------------------
Product     AmeriCa  88             $ 871,464    5/10/2016  Product
             res      Hamilto                                donation
             Founda   n Ave                                  for
             tion     Stamfor                                humanitaria
                      d, CT                                  n
                      06902                                  assistance
                                                             in USA
------------------------------------------------------------------------
Product     AmeriCa  88           $ 3,176,645    5/10/2016  Product
             res      Hamilto                                donation
             Founda   n Ave                                  for
             tion     Stamfor                                humanitaria
                      d, CT                                  n
                      06902                                  assistance
                                                             in
                                                             Afghanistan
                                                             , USA,
                                                             Armenia,
                                                             Nicaragua,
                                                             Peru, St.
                                                             Lucia, West
                                                             Bank
------------------------------------------------------------------------
Product     AmeriCa  88           $ 1,347,810    5/10/2016  Product
             res      Hamilto                                donation
             Founda   n Ave                                  for
             tion     Stamfor                                humanitaria
                      d, CT                                  n
                      06902                                  assistance
                                                             in
                                                             Afghanistan
                                                             , Armenia,
                                                             Nicaragua,
                                                             Peru, St.
                                                             Lucia, West
                                                             Bank
------------------------------------------------------------------------
Product     AmeriCa  88           $ 1,482,447    5/10/2016  Product
             res      Hamilto                                donation
             Founda   n Ave                                  for
             tion     Stamfor                                humanitaria
                      d, CT                                  n
                      06902                                  assistance
                                                             in
                                                             Tanzania,
                                                             Armenia,
                                                             St. Lucia,
                                                             Jamaica
------------------------------------------------------------------------
Product     AmeriCa  88             $ 133,034    5/10/2016  Product
             res      Hamilto                                donation
             Founda   n Ave                                  for
             tion     Stamfor                                humanitaria
                      d, CT                                  n
                      06902                                  assistance
                                                             in St.
                                                             Lucia,
                                                             Tanzania,
                                                             Afghanistan
------------------------------------------------------------------------
Product     AmeriCa  88              $ 15,673     6/8/2016  Product
             res      Hamilto                                donation
             Founda   n Ave                                  for
             tion     Stamfor                                humanitaria
                      d, CT                                  n
                      06902                                  assistance
                                                             in
                                                             Tanzania.
------------------------------------------------------------------------
Product     AmeriCa  88             $ 518,523     6/9/2016  Product
             res      Hamilto                                donation
             Founda   n Ave                                  for
             tion     Stamfor                                humanitaria
                      d, CT                                  n
                      06902                                  assistance
                                                             in
                                                             Nicaragua,
                                                             Tanzania,
                                                             West Bank,
                                                             and the US
------------------------------------------------------------------------
Product     AmeriCa  88           $ 1,087,540     6/9/2016  Product
             res      Hamilto                                donation
             Founda   n Ave                                  for
             tion     Stamfor                                humanitaria
                      d, CT                                  n
                      06902                                  assistance
                                                             in Gaza,
                                                             Sierra
                                                             Leone,
                                                             Tanzania,
                                                             West Bank,
                                                             Afghanistan
                                                             , and US
------------------------------------------------------------------------
Product     AmeriCa  88              $672,076     8/1/2016  Product
             res      Hamilto                                Donation
             Founda   n Ave                                  for
             tion     Stamfor                                humanitaria
                      d, CT                                  n
                      06902                                  assistance
                                                             in:
                                                             Dominican
                                                             Republic,
                                                             Lebanon,
                                                             Palestine
                                                             Territory,
                                                             Senegal,
                                                             St. Lucia,
                                                             Guatemala,
                                                             Nicaragua
                                                             and US
------------------------------------------------------------------------
Product     AmeriCa  88               $15,291     8/1/2016  Product
             res      Hamilto                                donation
             Founda   n Ave                                  for
             tion     Stamfor                                humanitaria
                      d, CT                                  n
                      06902                                  assistance
                                                             in
                                                             Guatemala,
                                                             Nicaragua,
                                                             Dominican
                                                             Republic.
------------------------------------------------------------------------
Product     AmeriCa  88              $536,094     8/1/2016  Product
             res      Hamilto                                donation
             Founda   n Ave                                  for
             tion     Stamfor                                humanitaria
                      d, CT                                  n
                      06902                                  assistance
                                                             in:
                                                             Dominican
                                                             Republic,
                                                             Lebanon,
                                                             Palestine
                                                             Territory,
                                                             Senegal,
                                                             Guatemala,
                                                             Nicaragua
------------------------------------------------------------------------
Product     AmeriCa  88            $2,923,869     8/1/2016  Product
             res      Hamilto                                Donation
             Founda   n Ave                                  for
             tion     Stamfor                                humanitaria
                      d, CT                                  n
                      06902                                  assistance
                                                             in:
                                                             Dominican
                                                             Republic,
                                                             Lebanon,
                                                             Palestine
                                                             Territory,
                                                             Senegal,
                                                             St. Lucia,
                                                             Guatemala,
                                                             Nicaragua,
                                                             US
------------------------------------------------------------------------
Product     AmeriCa  88               $83,360     8/1/2016  Product
             res      Hamilto                                donation
             Founda   n Ave                                  for
             tion     Stamfor                                humanitaria
                      d, CT                                  n
                      06902                                  assistance
                                                             in: Haiti,
                                                             Palestine
                                                             Territory,
                                                             St. Lucia,
                                                             Lebanon,
                                                             Senegal,
                                                             Jamaica
------------------------------------------------------------------------
Product     AmeriCa  88              $481,959     8/1/2016  Product
             res      Hamilto                                donation
             Founda   n Ave                                  for
             tion     Stamfor                                humanitaria
                      d, CT                                  n
                      06902                                  assistance
                                                             in:
                                                             Guatemala,
                                                             Nicaragua,
                                                             Palestine
                                                             Territory,
                                                             Senegal, US
------------------------------------------------------------------------
Product     AmeriCa  88              $354,276    9/13/2016  Product
             res      Hamilto                                donation
             Founda   n Ave                                  for
             tion     Stamfor                                humanitaria
                      d, CT                                  n
                      06902                                  assistance
                                                             in
                                                             Colombia,
                                                             Lebanon,
                                                             Tanzania
                                                             and West
                                                             Bank.
------------------------------------------------------------------------
Product     AmeriCa  88              $589,968    9/13/2016  Product
             res      Hamilto                                donation
             Founda   n Ave                                  for
             tion     Stamfor                                Americares
                      d, CT                                  US Clinics
                      06902                                  Network.
------------------------------------------------------------------------
Product     AmeriCa  88               $34,315    9/13/2016  Product
             res      Hamilto                                donation
             Founda   n Ave                                  for
             tion     Stamfor                                humanitaria
                      d, CT                                  n
                      06902                                  assistance
                                                             in Tanzania
                                                             and West
                                                             Bank.
------------------------------------------------------------------------
Product     AmeriCa  88              $114,481    9/13/2016  Product
             res      Hamilto                                donation
             Founda   n Ave                                  for
             tion     Stamfor                                humanitaria
                      d, CT                                  n
                      06902                                  assistance
                                                             in
                                                             Afghanistan
                                                             , Colombia,
                                                             Tanzania,
                                                             and West
                                                             Bank
------------------------------------------------------------------------
Product     AmeriCa  88              $613,250    9/21/2016  Product
             res      Hamilto                                donation
             Founda   n Ave                                  for
             tion     Stamfor                                humanitaria
                      d, CT                                  n
                      06902                                  assistance
                                                             in US
                                                             Clinics.
------------------------------------------------------------------------
Product     AmeriCa  88            $6,343,517    9/21/2016  Product
             res      Hamilto                                donation
             Founda   n Ave                                  for
             tion     Stamfor                                humanitaria
                      d, CT                                  n
                      06902                                  assistance
                                                             in Lebanon,
                                                             St. Lucia,
                                                             West Bank,
                                                             Gaza,
                                                             Afghanistan
                                                             and the US
------------------------------------------------------------------------
Product     AmeriCa  88              $807,284    9/21/2016  Product
             res      Hamilto                                donation
             Founda   n Ave                                  for
             tion     Stamfor                                humanitaria
                      d, CT                                  n
                      06902                                  assistance
                                                             in
                                                             Colombia,
                                                             West Bank,
                                                             Afghanistan
                                                             .
------------------------------------------------------------------------
Product     AmeriCa  88               $61,169    9/21/2016  Product
             res      Hamilto                                donation
             Founda   n Ave                                  for
             tion     Stamfor                                humanitaria
                      d, CT                                  n
                      06902                                  assistance
                                                             in St.
                                                             Lucia.
------------------------------------------------------------------------
Product     AmeriCa  88            $1,516,094    9/21/2016  Product
             res      Hamilto                                donation
             Founda   n Ave                                  for
             tion     Stamfor                                humanitaria
                      d, CT                                  n
                      06902                                  assistance
                                                             in West
                                                             Bank and
                                                             the US
------------------------------------------------------------------------
Product     AmeriCa  88              $252,240    9/21/2016  Product
             res      Hamilto                                donation
             Founda   n Ave                                  for
             tion     Stamfor                                humanitaria
                      d, CT                                  n
                      06902                                  assistance
                                                             in US
------------------------------------------------------------------------
Product     AmeriCa  88              $292,992    9/21/2016  Product
             res      Hamilto                                donation
             Founda   n Ave                                  for
             tion     Stamfor                                humanitaria
                      d, CT                                  n
                      06902                                  assistance
                                                             in US
                                                             Clinics.
------------------------------------------------------------------------
Product     AmeriCa  88            $1,270,212    9/21/2016  Product
             res      Hamilto                                donation
             Founda   n Ave                                  for
             tion     Stamfor                                humanitaria
                      d, CT                                  n
                      06902                                  assistance
                                                             in US
                                                             Clinics
------------------------------------------------------------------------
Product     AmeriCa  88              $641,091    9/21/2016  Product
             res      Hamilto                                donation
             Founda   n Ave                                  for
             tion     Stamfor                                humanitaria
                      d, CT                                  n
                      06902                                  assistance
                                                             in West
                                                             Bank and
                                                             the US
------------------------------------------------------------------------
Product     AmeriCa  88              $113,318    9/13/2016  Product
             res      Hamilto                                donation
             Founda   n Ave                                  for
             tion     Stamfor                                humanitaria
                      d, CT                                  n
                      06902                                  assistance
                                                             in
                                                             Afghanistan
                                                             , Colombia,
                                                             Tanzania,
                                                             West Bank.
------------------------------------------------------------------------
Product     AmeriCa  88              $622,686   10/24/2016  Product
             res      Hamilto                                donation
             Founda   n Ave                                  for
             tion     Stamfor                                humanitaria
                      d, CT                                  n
                      06902                                  assistance
                                                             in
                                                             Dominican
                                                             Republic.
------------------------------------------------------------------------
Product     AmeriCa  88               $42,437   10/24/2016  Product
             res      Hamilto                                donation
             Founda   n Ave                                  for
             tion     Stamfor                                humanitaria
                      d, CT                                  n
                      06902                                  assistance
                                                             in Haiti,
                                                             Sierra
                                                             Leone,
                                                             Ghana.
------------------------------------------------------------------------
Product     AmeriCa  88              $555,202   10/24/2016  Product
             res      Hamilto                                donation
             Founda   n Ave                                  for
             tion     Stamfor                                humanitaria
                      d, CT                                  n
                      06902                                  assistance
                                                             in West
                                                             Bank, Gaza,
                                                             US
------------------------------------------------------------------------
Product     AmeriCa  88            $1,321,288   11/17/2016  Product
             res      Hamilto                                donation
             Founda   n Ave                                  for
             tion     Stamfor                                humanitaria
                      d, CT                                  n
                      06902                                  assistance
                                                             in Puerto
                                                             Rico
------------------------------------------------------------------------
Product     AmeriCa  88               $99,595   11/22/2016  Product
             res      Hamilto                                Donation
             Founda   n Ave                                  for
             tion     Stamfor                                humanitaria
                      d, CT                                  n
                      06902                                  assistance
                                                             in St.
                                                             Lucia and
                                                             Colombia
------------------------------------------------------------------------
Product     AmeriCa  88               $25,655   11/29/2016  Product
             res      Hamilto                                donation
             Founda   n Ave                                  for
             tion     Stamfor                                humanitaria
                      d, CT                                  n
                      06902                                  assistance
                                                             in West
                                                             Bank, Gaza,
                                                             Dominican
                                                             Republic,
                                                             St. Lucia,
                                                             Colombia
------------------------------------------------------------------------
Product     AmeriCa  88              $151,578   11/29/2016  Product
             res      Hamilto                                donation
             Founda   n Ave                                  for
             tion     Stamfor                                humanitaria
                      d, CT                                  n
                      06902                                  assistance
                                                             in
                                                             Colombia.
------------------------------------------------------------------------
Product     AmeriCa  88               $38,160   11/29/2016  Product
             res      Hamilto                                donation
             Founda   n Ave                                  for
             tion     Stamfor                                humanitaria
                      d, CT                                  n
                      06902                                  assistance
                                                             in
                                                             Colombia.
------------------------------------------------------------------------
Product     AmeriCa  88              $119,132   11/29/2016  Product
             res      Hamilto                                donation
             Founda   n Ave                                  for
             tion     Stamfor                                humanitaria
                      d, CT                                  n
                      06902                                  assistance
                                                             in West
                                                             Bank and
                                                             St. Lucia.
------------------------------------------------------------------------
Product     AmeriCa  88              $238,579   11/29/2016  Product
             res      Hamilto                                donation
             Founda   n Ave                                  for
             tion     Stamfor                                humanitaria
                      d, CT                                  n
                      06902                                  assistance
                                                             in
                                                             Colombia.
------------------------------------------------------------------------
Product     AmeriCa  88              $381,064   11/30/2016  Produce
             res      Hamilto                                donation
             Founda   n Ave                                  for
             tion     Stamfor                                humanitaria
                      d, CT                                  n
                      06902                                  assistance
                                                             in
                                                             Nicaragua.
------------------------------------------------------------------------
Product     AmeriCa  88               $86,941   12/22/2016  Product
             res      Hamilto                                donation
             Founda   n Ave                                  for
             tion     Stamfor                                humanitaria
                      d, CT                                  n
                      06902                                  assistance
                                                             in
                                                             Nicaragua
                                                             and West
                                                             Bank.
------------------------------------------------------------------------
Product     AmeriCa  88              $239,612   12/22/2016  Product
             res      Hamilto                                donation
             Founda   n Ave                                  for
             tion     Stamfor                                humanitaria
                      d, CT                                  n
                      06902                                  assistance
                                                             in
                                                             Nicaragua,
                                                             St. Lucia.
------------------------------------------------------------------------
Product     AmeriCa  88               $46,647   12/22/2016  Product
             res      Hamilto                                donation
             Founda   n Ave                                  for
             tion     Stamfor                                humanitaria
                      d, CT                                  n
                      06902                                  assistance
                                                             in
                                                             Nicaragua.
------------------------------------------------------------------------
Product     AmeriCa  88               $10,987   12/22/2016  Product
             res      Hamilto                                donation
             Founda   n Ave                                  for
             tion     Stamfor                                humanitaria
                      d, CT                                  n
                      06902                                  assistance
                                                             in St.
                                                             Lucia.
------------------------------------------------------------------------
Product     AmeriCa  88              $145,709   12/22/2016  Product
             res      Hamilto                                donation
             Founda   n Ave                                  for
             tion     Stamfor                                humanitaria
                      d, CT                                  n
                      06902                                  assistance
                                                             in
                                                             Dominican
                                                             Republic,
                                                             Nicaragua,
                                                             West Bank
                                                             and US
------------------------------------------------------------------------
Product     AmeriCa  88               $23,053   12/22/2016  Product
             res      Hamilto                                donation
             Founda   n Ave                                  for
             tion     Stamfor                                humanitaria
                      d, CT                                  n
                      06902                                  assistance
                                                             in
                                                             Dominican
                                                             Republic.
------------------------------------------------------------------------
Product     AmeriCa  88              $282,912   12/22/2016  Product
             res      Hamilto                                donation
             Founda   n Ave                                  for
             tion     Stamfor                                humanitaria
                      d, CT                                  n
                      06902                                  assistance
                                                             in US
------------------------------------------------------------------------
Product     AmeriCa  88              $142,865   12/22/2016  Product
             res      Hamilto                                donation
             Founda   n Ave                                  for
             tion     Stamfor                                humanitaria
                      d, CT                                  n
                      06902                                  assistance
                                                             in
                                                             Afghanistan
                                                             ,
                                                             Nicaragua,
                                                             St. Lucia,
                                                             and West
                                                             Bank.
------------------------------------------------------------------------
Product     AmeriCa  88              $212,731   12/22/2016  Product
             res      Hamilto                                donation
             Founda   n Ave                                  for
             tion     Stamfor                                humanitaria
                      d, CT                                  n
                      06902                                  assistance
                                                             in
                                                             Afghanistan
                                                             and
                                                             Nicaragua.
------------------------------------------------------------------------
Product     AmeriCa  88               $54,332   12/22/2016  Product
             res      Hamilto                                donation
             Founda   n Ave                                  for
             tion     Stamfor                                humanitaria
                      d, CT                                  n
                      06902                                  assistance
                                                             in
                                                             Nicaragua
                                                             and
                                                             Liberia.
------------------------------------------------------------------------
Product     AmeriCa  88               $25,485   12/22/2016  Product
             res      Hamilto                                donation
             Founda   n Ave                                  for
             tion     Stamfor                                humanitaria
                      d, CT                                  n
                      06902                                  assistance
                                                             in US
------------------------------------------------------------------------
Product     AmeriCa  88              $183,120   12/22/2016  Product
             res      Hamilto                                donation
             Founda   n Ave                                  for
             tion     Stamfor                                humanitaria
                      d, CT                                  n
                      06902                                  assistance
                                                             in the US
------------------------------------------------------------------------
Product     AmeriCa  88              $179,712   12/19/2016  Product
             res      Hamilto                                donation
             Founda   n Ave                                  for
             tion     Stamfor                                humanitaria
                      d, CT                                  n
                      06902                                  assistance
                                                             in Romania.
------------------------------------------------------------------------
Product     AmeriCa  88              $428,182   12/21/2016  Product
             res      Hamilto                                donation
             Founda   n Ave                                  for
             tion     Stamfor                                humanitaria
                      d, CT                                  n
                      06902                                  assistance
                                                             in St.
                                                             Lucia.
------------------------------------------------------------------------
Product     AmeriCa  88              $270,923   12/22/2016  Product
             res      Hamilto                                donation
             Founda   n Ave                                  for
             tion     Stamfor                                humanitaria
                      d, CT                                  n
                      06902                                  assistance
                                                             in
                                                             Afghanistan
                                                             and
                                                             Tanzania.
------------------------------------------------------------------------
Product     AmeriCa  88               $30,737   12/22/2016  Product
             res      Hamilto                                donation
             Founda   n Ave                                  for
             tion     Stamfor                                humanitaria
                      d, CT                                  n
                      06902                                  assistance
                                                             in US
------------------------------------------------------------------------
Product     AmeriCa  88              $291,417   12/30/2016  Product
             res      Hamilto                                Donation
             Founda   n Ave                                  for
             tion     Stamfor                                humanitaria
                      d, CT                                  n
                      06902                                  assistance
                                                             in
                                                             Dominican
                                                             Republic,
                                                             Nicaragua,
                                                             West Bank,
                                                             and US
------------------------------------------------------------------------
Product     Catholi  100 Wall      $1,167,782   12/22/2016  Product
             c        Street,                                donation
             Medica   9th                                    for
             l        Floor                                  humanitaria
             Missio   New                                    n
             n        York,                                  assistance
             Board    NY                                     in D.R., El
                      10005                                  Salvador,
                                                             Guatemala,
                                                             Haiti,
                                                             Honduras.
------------------------------------------------------------------------
Product     Catholi  100 Wall         $30,737   12/22/2016  Product
             c        Street,                                donation
             Medica   9th                                    for
             l        Floor                                  humanitaria
             Missio   New                                    n
             n        York,                                  assistance
             Board    NY                                     in El
                      10005                                  Salvador.
------------------------------------------------------------------------
Product     Catholi  100 Wall         $30,737   12/22/2016  Product
             c        Street,                                donation
             Medica   9th                                    for
             l        Floor                                  humanitaria
             Missio   New                                    n
             n        York,                                  assistance
             Board    NY                                     in El
                      10005                                  Salvador.
------------------------------------------------------------------------
Product     Catholi  100 Wall     $12,212,928   12/21/2016  Product
             c        Street,                                donation
             Medica   9th                                    for
             l        Floor                                  humanitaria
             Missio   New                                    n
             n        York,                                  assistance
             Board    NY                                     in Haiti,
                      10005                                  Honduras,
                                                             Jamaica,
                                                             Dominican
                                                             Republic,
                                                             El
                                                             Salvador,
                                                             Guatemala
------------------------------------------------------------------------
Product     Catholi  100 Wall        $135,843   12/19/2016  Product
             c        Street,                                donation
             Medica   9th                                    for
             l        Floor                                  humanitaria
             Missio   New                                    n
             n        York,                                  assistance.
             Board    NY
                      10005
------------------------------------------------------------------------
Product     Catholi  100 Wall         $43,471   12/22/2016  Product
             c        Street,                                donation
             Medica   9th                                    for
             l        Floor                                  humanitaria
             Missio   New                                    n
             n        York,                                  assistance
             Board    NY                                     in Jamaica.
                      10005
------------------------------------------------------------------------
Product     Catholi  100 Wall        $374,394   12/22/2016  Product
             c        Street,                                donation
             Medica   9th                                    for
             l        Floor                                  humanitaria
             Missio   New                                    n
             n        York,                                  assistance
             Board    NY                                     in
                      10005                                  Dominican
                                                             Republic,
                                                             El
                                                             Salvador,
                                                             Guatemala.
------------------------------------------------------------------------
Product     Catholi  100 Wall         $42,860   12/22/2016  Product
             c        Street,                                donation
             Medica   9th                                    for
             l        Floor                                  humanitaria
             Missio   New                                    n
             n        York,                                  assistance
             Board    NY                                     in El
                      10005                                  Salvador.
------------------------------------------------------------------------
Product     Catholi  100 Wall        $106,365   12/22/2016  Product
             c        Street,                                donation
             Medica   9th                                    for
             l        Floor                                  humanitaria
             Missio   New                                    n
             n        York,                                  assistance
             Board    NY                                     in El
                      10005                                  Salvador.
------------------------------------------------------------------------
Product     Catholi  100 Wall         $27,166   12/22/2016  Product
             c        Street,                                donation
             Medica   9th                                    for
             l        Floor                                  humanitaria
             Missio   New                                    n
             n        York,                                  assistance
             Board    NY                                     in Jamaica.
                      10005
------------------------------------------------------------------------
Product     Catholi  100 Wall        $101,942   12/22/2016  Product
             c        Street,                                donation
             Medica   9th                                    for
             l        Floor                                  humanitaria
             Missio   New                                    n
             n        York,                                  assistance
             Board    NY                                     in El
                      10005                                  Salvador.
------------------------------------------------------------------------
Product     Catholi  100 Wall      $2,140,908   12/22/2016  Product
             c        Street,                                donation
             Medica   9th                                    for
             l        Floor                                  humanitaria
             Missio   New                                    n
             n        York,                                  assistance
             Board    NY                                     in
                      10005                                  Dominican
                                                             Republic,
                                                             El
                                                             Salvador,
                                                             Guatemala,
                                                             Haiti,
                                                             Honduras.
------------------------------------------------------------------------
Product     Catholi  100 Wall        $336,398   12/22/2016  Product
             c        Street,                                donation
             Medica   9th                                    for
             l        Floor                                  humanitaria
             Missio   New                                    n
             n        York,                                  assistance
             Board    NY                                     in
                      10005                                  Dominican
                                                             Republic,
                                                             El
                                                             Salvador,
                                                             Guatemala.
------------------------------------------------------------------------
Product     Catholi  100 Wall        $582,322   12/22/2016  Product
             c        Street,                                donation
             Medica   9th                                    for
             l        Floor                                  humanitaria
             Missio   New                                    n
             n        York,                                  assistance
             Board    NY                                     in
                      10005                                  Dominican
                                                             Republic,
                                                             El
                                                             Salvador,
                                                             Guatemala,
                                                             Haiti,
                                                             Honduras.
------------------------------------------------------------------------
Product     Catholi  100 Wall      $2,723,631   12/22/2016  Product
             c        Street,                                donation
             Medica   9th                                    for
             l        Floor                                  humanitaria
             Missio   New                                    n
             n        York,                                  assistance
             Board    NY                                     in
                      10005                                  Dominican
                                                             Republic,
                                                             El
                                                             Salvador,
                                                             Guatemala,
                                                             Haiti,
                                                             Honduras.
------------------------------------------------------------------------
Product     Catholi  100 Wall         $89,706   12/22/2016  Product
             c        Street,                                donation
             Medica   9th                                    for
             l        Floor                                  humanitaria
             Missio   New                                    n
             n        York,                                  assistance
             Board    NY                                     in El
                      10005                                  Salvador.
------------------------------------------------------------------------
Product     Catholi  100 Wall         $43,293    12/1/2016  Product
             c        Street,                                donation
             Medica   9th                                    for
             l        Floor                                  humanitaria
             Missio   New                                    n
             n        York,                                  assistance
             Board    NY                                     in Haiti,
                      10005                                  Jamaica and
                                                             El
                                                             Salvador.
------------------------------------------------------------------------
Product     Catholi  100 Wall        $223,922    12/1/2016  Product
             c        Street,                                donation
             Medica   9th                                    for
             l        Floor                                  humanitaria
             Missio   New                                    n
             n        York,                                  assistance
             Board    NY                                     in
                      10005                                  Guatemala,
                                                             Haiti,
                                                             Dominican
                                                             Republic.
------------------------------------------------------------------------
Product     Catholi  100 Wall        $218,883    12/1/2016  Product
             c        Street,                                donation
             Medica   9th                                    for
             l        Floor                                  humanitaria
             Missio   New                                    n
             n        York,                                  assistance
             Board    NY                                     in
                      10005                                  Guatemala,
                                                             Haiti,
                                                             Dominican
                                                             Republic.
------------------------------------------------------------------------
Product     Catholi  100 Wall         $41,696    12/1/2016  Product
             c        Street,                                donation
             Medica   9th                                    for
             l        Floor                                  humanitaria
             Missio   New                                    n
             n        York,                                  assistance
             Board    NY                                     in Haiti.
                      10005
------------------------------------------------------------------------
Product     Catholi  100 Wall     $26,039,346    12/1/2016  Product
             c        Street,                                donation
             Medica   9th                                    for
             l        Floor                                  humanitaria
             Missio   New                                    n
             n        York,                                  assistance
             Board    NY                                     in
                      10005                                  Guatemala,
                                                             Haiti,
                                                             Dominican
                                                             Republic,
                                                             El
                                                             Salvador.
------------------------------------------------------------------------
Product     Catholi  100 Wall        $248,988    12/1/2016  Product
             c        Street,                                donation
             Medica   9th                                    for
             l        Floor                                  humanitaria
             Missio   New                                    n
             n        York,                                  assistance
             Board    NY                                     in Haiti.
                      10005
------------------------------------------------------------------------
Product     Catholi  100 Wall        $381,604    12/1/2016  Product
             c        Street,                                donation
             Medica   9th                                    for
             l        Floor                                  humanitaria
             Missio   New                                    n
             n        York,                                  assistance
             Board    NY                                     in Haiti
                      10005                                  and
                                                             Dominican
                                                             Republic.
------------------------------------------------------------------------
Product     Catholi  100 Wall        $361,008    12/1/2016  Product
             c        Street,                                donation
             Medica   9th                                    for
             l        Floor                                  humanitaria
             Missio   New                                    n
             n        York,                                  assistance
             Board    NY                                     in
                      10005                                  Guatemala
                                                             and Haiti.
------------------------------------------------------------------------
Product     Catholi  33-01            $76,321    9/13/2016  Product
             c        Elevent                                donation
             Medica   h                                      for
             l        Street                                 humanitaria
             Missio   Long                                   n
             n        Island                                 assistance
             Board    City,                                  in Haiti.
                      NY
------------------------------------------------------------------------
Product     Catholi  100 Wall        $622,686   10/25/2016  Product
             c        Street,                                donation
             Medica   9th                                    for
             l        Floor                                  humanitaria
             Missio   New                                    n
             n        York,                                  assistance
             Board    NY                                     in El
                      10005                                  Salvador,
                                                             Guatemala
------------------------------------------------------------------------
Product     Catholi  100 Wall        $482,784   10/25/2016  Product
             c        Street,                                donation
             Medica   9th                                    for
             l        Floor                                  humanitaria
             Missio   New                                    n
             n        York,                                  assistance
             Board    NY                                     in El
                      10005                                  Salvador
                                                             and
                                                             Guatemala.
------------------------------------------------------------------------
Product     Catholi  100 Wall     $16,848,000   10/25/2016  Product
             c        Street,                                donation
             Medica   9th                                    for
             l        Floor                                  humanitaria
             Missio   New                                    n
             n        York,                                  assistance
             Board    NY                                     in
                      10005                                  Guatemala.
------------------------------------------------------------------------
Product     Catholi  33-01           $822,943    9/22/2016  Product
             c        Elevent                                donation
             Medica   h                                      for
             l        Street                                 humanitaria
             Missio   Long                                   n relief in
             n        Island                                 Honduras.
             Board    City,
                      NY
------------------------------------------------------------------------
Product     Catholi  33-01           $139,387    9/22/2016  Product
             c        Elevent                                donation
             Medica   h                                      for
             l        Street                                 humanitaria
             Missio   Long                                   n
             n        Island                                 assistance
             Board    City,                                  in
                      NY                                     Honduras.
------------------------------------------------------------------------
Product     Catholi  33-01           $732,675    9/22/2016  Product
             c        Elevent                                donation
             Medica   h                                      for
             l        Street                                 humanitaria
             Missio   Long                                   n
             n        Island                                 assistance
             Board    City,                                  in
                      NY                                     Honduras.
------------------------------------------------------------------------
Product     Catholi  33-01            $76,696    9/13/2016  Product
             c        Elevent                                donation
             Medica   h                                      for
             l        Street                                 humanitaria
             Missio   Long                                   n
             n        Island                                 assistance
             Board    City,                                  in Haiti.
                      NY
------------------------------------------------------------------------
Product     Catholi  33-01            $30,737    9/13/2016  Product
             c        Elevent                                Donation
             Medica   h                                      for
             l        Street                                 humanitaria
             Missio   Long                                   n
             n        Island                                 assistance
             Board    City,                                  in Haiti.
                      NY
------------------------------------------------------------------------
Product     Catholi  33-01            $75,546    9/13/2016  Product
             c        Elevent                                donation
             Medica   h                                      for
             l        Street                                 humanitaria
             Missio   Long                                   n
             n        Island                                 assistance
             Board    City,                                  in Haiti.
                      NY
------------------------------------------------------------------------
Product     Catholi  33-01           $270,923    9/13/2016  Product
             c        Elevent                                donation
             Medica   h                                      for
             l        Street                                 humanitaria
             Missio   Long                                   n
             n        Island                                 assistance
             Board    City,                                  in Haiti.
                      NY
------------------------------------------------------------------------
Product     Catholi  33-01           $151,003    9/13/2016  Product
             c        Elevent                                donation
             Medica   h                                      for
             l        Street                                 humanitaria
             Missio   Long                                   n
             n        Island                                 assistance
             Board    City,                                  in Haiti.
                      NY
------------------------------------------------------------------------
Product     Catholi  100 Wall        $275,235     8/1/2016  Product
             c        Street,                                donation
             Medica   9th                                    for
             l        Floor                                  humanitaria
             Missio   New                                    n
             n        York,                                  assistance
             Board    NY                                     in
                      10005                                  Guatemala
                                                             and
                                                             Nicaragua.
------------------------------------------------------------------------
Product     Catholi  100 Wall         $48,005     8/1/2016  Product
             c        Street,                                donation
             Medica   9th                                    for
             l        Floor                                  humanitaria
             Missio   New                                    n
             n        York,                                  assistance
             Board    NY                                     in
                      10005                                  Guatemala
                                                             and
                                                             Nicaragua.
------------------------------------------------------------------------
Product     Catholi  100 Wall        $208,481     8/1/2016  Product
             c        Street,                                donation
             Medica   9th                                    for
             l        Floor                                  humanitaria
             Missio   New                                    n
             n        York,                                  assistance
             Board    NY                                     in
                      10005                                  Guatemala
                                                             and
                                                             Nicaragua.
------------------------------------------------------------------------
Product     Catholi  100 Wall      $1,162,207     8/1/2016  Product
             c        Street,                                donation
             Medica   9th                                    for
             l        Floor                                  humanitaria
             Missio   New                                    n
             n        York,                                  assistance
             Board    NY                                     in
                      10005                                  Guatemala
                                                             and
                                                             Nicaragua.
------------------------------------------------------------------------
Product     Catholi  100 Wall          $4,168     8/1/2016  Product
             c        Street,                                donation
             Medica   9th                                    for
             l        Floor                                  humanitaria
             Missio   New                                    n
             n        York,                                  assistance
             Board    NY                                     in Jamaica.
                      10005
------------------------------------------------------------------------
Product     Catholi  100 Wall        $952,711     8/1/2016  Product
             c        Street,                                donation
             Medica   9th                                    for
             l        Floor                                  humanitaria
             Missio   New                                    n
             n        York,                                  assistance
             Board    NY                                     in
                      10005                                  Guatemala
                                                             and
                                                             Nicaragua.
------------------------------------------------------------------------
Product     Catholi  33-01            $15,673     6/8/2016  Product
             c        Elevent                                donation
             Medica   h                                      for
             l        Street                                 humanitaria
             Missio   Long                                   n
             n        Island                                 assistance
             Board    City,                                  in
                      NY                                     Nicaragua
------------------------------------------------------------------------
Product     Catholi  33-01           $884,080     6/9/2016  Product
             c        Elevent                                donation
             Medica   h                                      for
             l        Street                                 humanitaria
             Missio   Long                                   n
             n        Island                                 assistance
             Board    City,                                  in
                      NY                                     Nicaragua
------------------------------------------------------------------------
Product     Catholi  33-01           $294,990     6/9/2016  Product
             c        Elevent                                donation
             Medica   h                                      for
             l        Street                                 humanitaria
             Missio   Long                                   n
             n        Island                                 assistance
             Board    City,                                  in
                      NY                                     Nicaragua.
------------------------------------------------------------------------
Product     Catholi  33-01            $97,026    5/10/2016  Product
             c        Elevent                                donation
             Medica   h                                      for
             l        Street                                 humanitaria
             Missio   Long                                   n
             n        Island                                 assistance
             Board    City,                                  in
                      NY                                     Nicaragua
------------------------------------------------------------------------
Product     Catholi  33-01           $137,045    5/10/2016  Product
             c        Elevent                                donation
             Medica   h                                      for
             l        Street                                 humanitaria
             Missio   Long                                   n
             n        Island                                 assistance
             Board    City,                                  in
                      NY                                     Nicaragua
------------------------------------------------------------------------
Product     Catholi  33-01           $561,881    5/10/2016  Product
             c        Elevent                                donation
             Medica   h                                      for
             l        Street                                 humanitaria
             Missio   Long                                   n
             n        Island                                 assistance
             Board    City,                                  in Armenia,
                      NY                                     Guatemala,
                                                             Honduras,
                                                             El Salvador
------------------------------------------------------------------------
Product     Catholi  33-01         $3,165,318    5/10/2016  Product
             c        Elevent                                donation
             Medica   h                                      for
             l        Street                                 humanitaria
             Missio   Long                                   n
             n        Island                                 assistance
             Board    City,                                  in
                      NY                                     Dominican
                                                             Republic,
                                                             El
                                                             Salvador,
                                                             Haiti,
                                                             Jamaica
------------------------------------------------------------------------
Product     Catholi  33-01           $439,527    4/27/2016  Product
             c        Elevent                                donation
             Medica   h                                      for
             l        Street                                 humanitaria
             Missio   Long                                   n
             n        Island                                 assistance
             Board    City,                                  in
                      NY                                     Dominican
                                                             Republic,
                                                             Haiti,
                                                             Jamaica,
                                                             Honduras
------------------------------------------------------------------------
Product     Catholi  33-01           $864,289    4/27/2016  Product
             c        Elevent                                donation
             Medica   h                                      for
             l        Street                                 humanitaria
             Missio   Long                                   n
             n        Island                                 assistance
             Board    City,                                  in
                      NY                                     Dominican
                                                             Republic,
                                                             Armenia,
                                                             Haiti,
                                                             Jamaica, El
                                                             Salvador
------------------------------------------------------------------------
Product     Direct   27 S. La      $1,970,703    4/27/2016  Product
             Relief   Patera                                 donation
                      Lane                                   for
                      Santa                                  humanitaria
                      Barbara                                n
                      , CA                                   assistance
                      93117                                  in Ecuador,
                                                             Guatemala,
                                                             Honduras,
                                                             Liberia,
                                                             Paraguay,
                                                             Peru,
                                                             Dominican
                                                             Republic,
                                                             Ghana,
                                                             Haiti
------------------------------------------------------------------------
Product     Direct   27 S. La      $2,216,643    4/27/2016  Product
             Relief   Patera                                 donation
                      Lane                                   for
                      Santa                                  humanitaria
                      Barbara                                n
                      , CA                                   assistance
                      93117                                  in Ghana,
                                                             Honduras,
                                                             Jordan,
                                                             Liberia,
                                                             Malawi,
                                                             Paraguay,
                                                             Peru,
                                                             Sierra
                                                             Leone,
                                                             Guatemala,
                                                             Haiti
------------------------------------------------------------------------
Product     Direct   27 S. La         $68,096     4/4/2016  Product
             Relief   Patera                                 donation
                      Lane                                   for
                      Santa                                  disaster
                      Barbara                                preparednes
                      , CA                                   s module
                      93117
------------------------------------------------------------------------
Product     Direct   27 S. La        $571,913    4/27/2016  Product
             Relief   Patera                                 donation
                      Lane                                   for
                      Santa                                  humanitaria
                      Barbara                                n
                      , CA                                   assistance
                      93117                                  in
                                                             Nicaragua,
                                                             Malawi,
                                                             Ghana, US
------------------------------------------------------------------------
Product     Direct   27 S. La      $1,270,853    4/27/2016  Product
             Relief   Patera                                 donation
                      Lane                                   for
                      Santa                                  humanitaria
                      Barbara                                n
                      , CA                                   assistance
                      93117                                  in
                                                             Colombia,
                                                             Ghana,
                                                             Guatemala,
                                                             Honduras,.
                                                             Jordan,
                                                             Paraguay
------------------------------------------------------------------------
Product     Direct   27 S. La        $172,405     6/8/2016  Product
             Relief   Patera                                 donation
                      Lane                                   for
                      Santa                                  humanitaria
                      Barbara                                n
                      , CA                                   assistance
                      93117                                  in
                                                             Dominican
                                                             Republic,
                                                             Ghana,
                                                             Pakistan,
                                                             Paraguay.
------------------------------------------------------------------------
Product     Direct   27 S. La      $3,702,692    5/10/2016  Product
             Relief   Patera                                 donation
                      Lane                                   for
                      Santa                                  humanitaria
                      Barbara                                n
                      , CA                                   assistance
                      93117                                  in Guyana,
                                                             Armenia
------------------------------------------------------------------------
Product     Direct   27 S. La        $114,204    5/10/2016  Product
             Relief   Patera                                 donation
                      Lane                                   for
                      Santa                                  humanitaria
                      Barbara                                n
                      , CA                                   assistance
                      93117                                  in Guyana
------------------------------------------------------------------------
Product     Direct   27 S. La      $4,350,366     6/9/2016  Product
             Relief   Patera                                 donation
                      Lane                                   for
                      Santa                                  humanitaria
                      Barbara                                n
                      , CA                                   assistance
                      93117                                  in
                                                             Dominican
                                                             Republic,
                                                             Ghana,
                                                             Jamaica,
                                                             Pakistan,
                                                             Paraguay,
                                                             Liberia,
                                                             and
                                                             Honduras
------------------------------------------------------------------------
Product     Direct   27 S. La      $2,620,434     6/9/2016  Product
             Relief   Patera                                 donation
                      Lane                                   for
                      Santa                                  humanitaria
                      Barbara                                n
                      , CA                                   assistance
                      93117                                  in Ghana,
                                                             Haiti,
                                                             Paraguay,
                                                             Somaliland,
                                                             Dominican
                                                             Republic,
                                                             Honduras,
                                                             Jamaica,
                                                             Malawi,
                                                             Pakistan,
                                                             Rwanda.
------------------------------------------------------------------------
Product     Direct   27 S. La         $20,006     8/2/2016  Product
             Relief   Patera                                 donation
                      Lane                                   for
                      Santa                                  humanitaria
                      Barbara                                n
                      , CA                                   assistance
                      93117                                  in Haiti.
------------------------------------------------------------------------
Product     Direct   27 S. La         $91,508     9/7/2016  Product
             Relief   Patera                                 donation
                      Lane                                   for
                      Santa                                  humanitaria
                      Barbara                                n
                      , CA                                   assistance
                      93117                                  in the
                                                             Dominican
                                                             Republic.
------------------------------------------------------------------------
Product     Direct   27 S. La      $1,368,726     9/7/2016  Product
             Relief   Patera                                 donation
                      Lane                                   for
                      Santa                                  humanitaria
                      Barbara                                n
                      , CA                                   assistance
                      93117                                  in
                                                             Dominican
                                                             Republic,
                                                             Guyana,
                                                             Fiji.
------------------------------------------------------------------------
Product     Direct   27 S. La         $30,737     9/7/2016  Product
             Relief   Patera                                 donation
                      Lane                                   for
                      Santa                                  humanitaria
                      Barbara                                n
                      , CA                                   assistance
                      93117                                  in
                                                             Nicaragua.
------------------------------------------------------------------------
Product     Direct   27 S. La        $812,768     9/7/2016  Product
             Relief   Patera                                 donation
                      Lane                                   for
                      Santa                                  humanitaria
                      Barbara                                n
                      , CA                                   assistance
                      93117                                  in
                                                             Dominican
                                                             Republic.
------------------------------------------------------------------------
Product     Direct   27 S. La        $300,317     9/7/2016  Product
             Relief   Patera                                 donation
                      Lane                                   for
                      Santa                                  humanitaria
                      Barbara                                n
                      , CA                                   assistance
                      93117                                  in
                                                             Dominican
                                                             Republic
                                                             and Guyana.
------------------------------------------------------------------------
Product     Direct   27 S. La        $572,406     9/7/2016  Product
             Relief   Patera                                 donation
                      Lane                                   for
                      Santa                                  humanitaria
                      Barbara                                n
                      , CA                                   assistance
                      93117                                  in
                                                             Dominican
                                                             Republic
                                                             and Guyana.
------------------------------------------------------------------------
Product     Direct   27 S. La        $423,969     9/7/2016  Product
             Relief   Patera                                 donation
                      Lane                                   for
                      Santa                                  humanitaria
                      Barbara                                n
                      , CA                                   assistance
                      93117                                  in
                                                             Dominican
                                                             Republic
                                                             and
                                                             Honduras.
------------------------------------------------------------------------
Product     Direct   27 S. La        $996,184   11/16/2016  Product
             Relief   Patera                                 donation
                      Lane                                   for
                      Santa                                  humanitaria
                      Barbara                                n
                      , CA                                   assistance
                      93117                                  in Ghana
------------------------------------------------------------------------
Product     Direct   27 S. La        $159,065   11/16/2016  Product
             Relief   Patera                                 donation
                      Lane                                   for
                      Santa                                  humanitaria
                      Barbara                                n
                      , CA                                   assistance
                      93117                                  in Ghana
------------------------------------------------------------------------
Product     Direct   27 S. La        $296,198   11/16/2016  Product
             Relief   Patera                                 donation
                      Lane                                   for
                      Santa                                  humanitaria
                      Barbara                                n
                      , CA                                   assistance
                      93117                                  in Ghana
------------------------------------------------------------------------
Product     Direct   27 S. La        $113,778   11/16/2016  Product
             Relief   Patera                                 donation
                      Lane                                   for
                      Santa                                  humanitaria
                      Barbara                                n
                      , CA                                   assistance
                      93117                                  in Ghana
------------------------------------------------------------------------
Product     Direct   27 S. La         $70,614   11/16/2016  Product
             Relief   Patera                                 donation
                      Lane                                   for
                      Santa                                  humanitaria
                      Barbara                                n
                      , CA                                   assistance
                      93117                                  in Ghana
------------------------------------------------------------------------
Product     Direct   27 S. La         $56,506   11/16/2016  Product
             Relief   Patera                                 donation
                      Lane                                   for
                      Santa                                  humanitaria
                      Barbara                                n
                      , CA                                   assistance
                      93117                                  in Ghana
------------------------------------------------------------------------
Product     Direct   27 S. La        $801,421   11/16/2016  Product
             Relief   Patera                                 donation
                      Lane                                   for
                      Santa                                  humanitaria
                      Barbara                                n
                      , CA                                   assistance
                      93117                                  in Ghana
------------------------------------------------------------------------
Product     Direct   27 S. La        $720,416   11/16/2016  Product
             Relief   Patera                                 donation
                      Lane                                   for
                      Santa                                  humanitaria
                      Barbara                                n
                      , CA                                   assistance
                      93117                                  in Ghana
------------------------------------------------------------------------
Product     Direct   27 S. La        $848,095   11/16/2016  Product
             Relief   Patera                                 donation
                      Lane                                   for
                      Santa                                  humanitaria
                      Barbara                                n
                      , CA                                   assistance
                      93117                                  in Ghana
------------------------------------------------------------------------
Product     Direct   27 S. La         $22,144    5/10/2016  Product
             Relief   Patera                                 donation
                      Lane                                   for
                      Santa                                  humanitaria
                      Barbara                                n
                      , CA                                   assistance
                      93117                                  in USA
------------------------------------------------------------------------
Product     Direct   27 S. La      $1,151,659   10/24/2016  Product
             Relief   Patera                                 donation
                      Lane                                   for
                      Santa                                  humanitaria
                      Barbara                                n
                      , CA                                   assistance
                      93117                                  in Haiti,
                                                             Ghana,
                                                             Sierra
                                                             Leone.
------------------------------------------------------------------------
Product     Direct   27 S. La      $1,781,473   10/24/2016  Product
             Relief   Patera                                 donation
                      Lane                                   for
                      Santa                                  humanitaria
                      Barbara                                n
                      , CA                                   assistance
                      93117                                  in Honduras
------------------------------------------------------------------------
Product     Direct   27 S. La         $49,798   11/22/2016  Product
             Relief   Patera                                 donation
                      Lane                                   for
                      Santa                                  humanitaria
                      Barbara                                n
                      , CA                                   assistance
                      93117                                  in Jamaica.
------------------------------------------------------------------------
Product     Direct   27 S. La         $18,947   11/22/2016  Product
             Relief   Patera                                 donation
                      Lane                                   for
                      Santa                                  humanitaria
                      Barbara                                n
                      , CA                                   assistance
                      93117                                  in Peru and
                                                             Nicaragua.
------------------------------------------------------------------------
Product     Direct   27 S. La         $21,529   11/22/2016  Product
             Relief   Patera                                 donation
                      Lane                                   for
                      Santa                                  humanitaria
                      Barbara                                n
                      , CA                                   assistance
                      93117                                  in Peru.
------------------------------------------------------------------------
Product     Direct   27 S. La        $152,642   11/22/2016  Product
             Relief   Patera                                 donation
                      Lane                                   for
                      Santa                                  humanitaria
                      Barbara                                n
                      , CA                                   assistance
                      93117                                  in Jamaica
                                                             and
                                                             Nicaragua.
------------------------------------------------------------------------
Product     Direct   27 S. La        $244,221   11/22/2016  Product
             Relief   Patera                                 donation
                      Lane                                   for
                      Santa                                  humanitaria
                      Barbara                                n
                      , CA                                   assistance
                      93117                                  in Jamaica,
                                                             Guatemala,
                                                             Colombia,
                                                             Nicaragua
------------------------------------------------------------------------
Product     Direct   27 S. La         $54,936   11/22/2016  Product
             Relief   Patera                                 donation
                      Lane                                   for
                      Santa                                  humanitaria
                      Barbara                                n
                      , CA                                   assistance
                      93117                                  in Peru,
                                                             Nicaragua
                                                             and
                                                             Colombia.
------------------------------------------------------------------------
Product     Direct   27 S. La         $86,941   12/22/2016  Product
             Relief   Patera                                 donation
                      Lane                                   for
                      Santa                                  humanitaria
                      Barbara                                n
                      , CA                                   assistance
                      93117                                  in Honduras
                                                             and
                                                             Afghanistan
                                                             .
------------------------------------------------------------------------
Product     Direct   27 S. La        $381,882   12/22/2016  Product
             Relief   Patera                                 donation
                      Lane                                   for
                      Santa                                  humanitaria
                      Barbara                                n
                      , CA                                   assistance
                      93117                                  in Haiti,
                                                             Afghanistan
                                                             , Honduras.
------------------------------------------------------------------------
Product     Direct   27 S. La         $64,354   12/22/2016  Product
             Relief   Patera                                 donation
                      Lane                                   for
                      Santa                                  humanitaria
                      Barbara                                n
                      , CA                                   assistance
                      93117                                  in US
------------------------------------------------------------------------
Product     Direct   27 S. La        $145,709   12/22/2016  Product
             Relief   Patera                                 donation
                      Lane                                   for
                      Santa                                  humanitaria
                      Barbara                                n
                      , CA                                   assistance
                      93117                                  in US
------------------------------------------------------------------------
Product     Direct   27 S. La         $57,146   12/22/2016  Product
             Relief   Patera                                 donation
                      Lane                                   for
                      Santa                                  humanitaria
                      Barbara                                n
                      , CA                                   assistance
                      93117                                  in Lebanon
                                                             and
                                                             Honduras.
------------------------------------------------------------------------
Product     Direct   27 S. La         $53,183   12/22/2016  Product
             Relief   Patera                                 donation
                      Lane                                   for
                      Santa                                  humanitaria
                      Barbara                                n
                      , CA                                   assistance
                      93117                                  in
                                                             Afghanistan
                                                             .
------------------------------------------------------------------------
Product     Direct   27 S. La         $45,277   12/22/2016  Product
             Relief   Patera                                 donation
                      Lane                                   for
                      Santa                                  humanitaria
                      Barbara                                n
                      , CA                                   assistance
                      93117                                  in
                                                             Afghanistan
                                                             and
                                                             Honduras.
------------------------------------------------------------------------
Product     Direct   27 S. La        $203,883   12/22/2016  Product
             Relief   Patera                                 donation
                      Lane                                   for
                      Santa                                  humanitaria
                      Barbara                                n relief in
                      , CA                                   Honduras
                      93117                                  and US.
------------------------------------------------------------------------
Product     Direct   27 S. La        $241,908   12/22/2016  Product
             Relief   Patera                                 donation
                      Lane                                   for
                      Santa                                  humanitaria
                      Barbara                                n
                      , CA                                   assistance
                      93117                                  in Haiti
                                                             and US
------------------------------------------------------------------------
Product     Direct   27 S. La        $102,180   12/22/2016  Product
             Relief   Patera                                 donation
                      Lane                                   for
                      Santa                                  humanitaria
                      Barbara                                n
                      , CA                                   assistance
                      93117                                  in the US
------------------------------------------------------------------------
Product     Direct   27 S. La        $126,300   12/22/2016  Product
             Relief   Patera                                 donation
                      Lane                                   for
                      Santa                                  humanitaria
                      Barbara                                n
                      , CA                                   assistance
                      93117                                  in Haiti.
------------------------------------------------------------------------
Product     Direct   27 S. La          $8,017   11/28/2016  Product
             Relief   Patera                                 donation
                      Lane                                   for
                      Santa                                  humanitaria
                      Barbara                                n
                      , CA                                   assistance
                      93117                                  in Peru.
------------------------------------------------------------------------
Product     Direct   27 S. La        $179,712   12/19/2016  Product
             Relief   Patera                                 donation
                      Lane                                   for
                      Santa                                  humanitaria
                      Barbara                                n
                      , CA                                   assistance
                      93117                                  in Malawi.
------------------------------------------------------------------------
Product     Heart    13250 W           $8,017   11/28/2016  Product
             To       98th                                   donation
             Heart    Street                                 for
             Intern   Lenexa,                                humanitaria
             ationa   KS                                     n
             l        66215                                  assistance
                                                             in
                                                             Honduras.
------------------------------------------------------------------------
Product     Heart    13250 W         $199,190   11/28/2016  Product
             To       98th                                   donation
             Heart    Street                                 for
             Intern   Lenexa,                                humanitaria
             ationa   KS                                     n
             l        66215                                  assistance
                                                             in Haiti.
------------------------------------------------------------------------
Product     Heart    13250 W         $190,802   11/28/2016  Product
             To       98th                                   donation
             Heart    Street                                 for
             Intern   Lenexa,                                humanitaria
             ationa   KS                                     n
             l        66215                                  assistance
                                                             in Honduras
------------------------------------------------------------------------
Product     Heart    13250 W          $83,392   11/28/2016  Product
             To       98th                                   donation
             Heart    Street                                 for
             Intern   Lenexa,                                humanitaria
             ationa   KS                                     n
             l        66215                                  assistance
                                                             in
                                                             Dominican
                                                             Republic,
                                                             Honduras.
------------------------------------------------------------------------
Product     Heart    13250 W         $635,226    9/26/2016  Product
             To       98th                                   donation
             Heart    Street                                 for
             Intern   Lenexa,                                humanitaria
             ationa   KS                                     n
             l        66215                                  assistance
                                                             in Haiti.
------------------------------------------------------------------------
Product     Heart    13250 W         $194,454    9/16/2016  Product
             To       98th                                   donation
             Heart    Street                                 for
             Intern   Lenexa,                                humanitaria
             ationa   KS                                     n
             l        66215                                  assistance
                                                             in Haiti
                                                             and
                                                             Guatemala
------------------------------------------------------------------------
Product     Heart    13250 W       $1,327,428    9/16/2016  Product
             To       98th                                   donation
             Heart    Street                                 for
             Intern   Lenexa,                                humanitaria
             ationa   KS                                     n
             l        66215                                  assistance
                                                             in Haiti,
                                                             Guatemala
                                                             and
                                                             Honduras.
------------------------------------------------------------------------
Product     Heart    13250 W         $114,481    9/16/2016  Product
             To       98th                                   donation
             Heart    Street                                 for
             Intern   Lenexa,                                humanitaria
             ationa   KS                                     n
             l        66215                                  assistance
                                                             in Haiti.
------------------------------------------------------------------------
Product     Heart    13250 W          $61,475    9/16/2016  Product
             To       98th                                   donation
             Heart    Street                                 for
             Intern   Lenexa,                                humanitaria
             ationa   KS                                     n
             l        66215                                  assistance
                                                             in
                                                             Guatemala
                                                             and El
                                                             Salvador.
------------------------------------------------------------------------
Product     Heart    13250 W         $128,184    9/16/2016  Product
             To       98th                                   donation
             Heart    Street                                 for
             Intern   Lenexa,                                humanitaria
             ationa   KS                                     n
             l        66215                                  assistance
                                                             in Haiti
                                                             and
                                                             Guatemala.
------------------------------------------------------------------------
Product     Heart    1021            $148,499     6/9/2016  Product
             to       Pacific                                donation
             Heart    Avenue                                 for
             Intern   Kansas                                 humanitaria
             ationa   City,                                  n
             l        KS                                     assistance
                      66102                                  in
                                                             Dominican
                                                             Republic,
                                                             Guatemala,
                                                             Jamaica
------------------------------------------------------------------------
Product     Heart    1021             $31,346     6/8/2016  Product
             to       Pacific                                donation
             Heart    Avenue                                 for
             Intern   Kansas                                 humanitaria
             ationa   City,                                  n
             l        KS                                     assistance
                      66102                                  in
                                                             Guatemala,
                                                             Jamaica.
------------------------------------------------------------------------
Product     Heart    13250 W         $963,188    5/10/2016  Product
             To       98th                                   donation
             Heart    Street                                 for
             Intern   Lenexa,                                humanitaria
             ationa   KS                                     n
             l        66215                                  assistance
                                                             in
                                                             Dominican
                                                             Republic
------------------------------------------------------------------------
Product     Heart    13250 W         $808,425    5/10/2016  Product
             To       98th                                   donation
             Heart    Street                                 for
             Intern   Lenexa,                                humanitaria
             ationa   KS                                     n
             l        66215                                  assistance
                                                             in
                                                             Swaziland
------------------------------------------------------------------------
Product     Johnson  One          $84,928,778    3/31/2016  Patient
             and      Johnson                                Assistance
             Johnso   &                                      Product
             n        Johnson                                Donation
             Patien   Plaza
             t        New
             Assist   Brunswi
             ance     ck, NJ
             Founda   08933
             tion
------------------------------------------------------------------------
Product     Johnson  One          $86,415,842    6/31/2016  Patient
             &        Johnson                                Assistance
             Johnso   &                                      Product
             n        Johnson                                Donation
             Patien   Plaza
             t        New
             Assist   Brunswi
             ance     ck, NJ
             Founda   08934
             tion
------------------------------------------------------------------------
Product     Johnson  One          $68,286,613    9/30/2016  Patient
             &        Johnson                                Assistance
             Johnso   &                                      Product
             n        Johnson                                Donation
             Patien   Plaza
             t        New
             Assist   Brunswi
             ance     ck, NJ
             Founda   08935
             tion
------------------------------------------------------------------------
Product     Johnson  One          $77,655,085   12/31/2016  Patient
             &        Johnson                                Assistance
             Johnso   &                                      Product
             n        Johnson                                Donation
             Patien   Plaza
             t        New
             Assist   Brunswi
             ance     ck, NJ
             Founda   08936
             tion
------------------------------------------------------------------------
Product     MAP      4700            $168,361   10/21/2016  Product
             Intern   Glynco                                 donation
             ationa   Parkway                                for
             l        Brunswi                                disaster
                      ck, GA                                 response in
                      31525                                  Haiti.
------------------------------------------------------------------------
Product     MAP      4700             $35,275   11/28/2016  Product
             Intern   Glynco                                 donation
             ationa   Parkway                                for
             l        Brunswi                                humanitaria
                      ck, GA                                 n
                      31525                                  assistance
                                                             in Central
                                                             America.
------------------------------------------------------------------------
Product     MAP      4700          $1,600,598   12/14/2016  Product
             Intern   Glynco                                 donation
             ationa   Parkway                                for
             l        Brunswi                                Humanitaria
                      ck, GA                                 n
                      31525                                  assistance
                                                             in
                                                             Dominican
                                                             Republic.
------------------------------------------------------------------------
Product     MAP      4700              $1,816   12/14/2016  Product
             Intern   Glynco                                 donation
             ationa   Parkway                                for
             l        Brunswi                                humanitaria
                      ck, GA                                 n
                      31525                                  assistance
                                                             in
                                                             Dominican
                                                             Republic
------------------------------------------------------------------------
Product     MAP      50 Hurt       $1,471,357   12/16/2016  Product
             Intern   Plaza                                  donation
             ationa   Atlanta                                for
             l        , GA                                   humanitaria
                      30303                                  n
                                                             assistance
                                                             in
                                                             Dominican
                                                             Republic
------------------------------------------------------------------------
Updated March 30, 2017


  Janssen Therapeutics, Division of Janssen Products, LP, Monetary and
  Product Contribution to U.S.-based Charitable Organizations Full Year
                                  2016
        (Payments made from January 1, 2016 to December 31, 2016)
------------------------------------------------------------------------
                                                               Project
 Donation    Payee     Payee   Payment Amount    Payment       Title/
   Type               Address       (USD)          Date      Description
------------------------------------------------------------------------
Monetary    Acercam  827               $7,500    4/25/2016  ContraSIDA
             iento    Wildwoo                                (Against
             Hispan   d Ave,                                 HIV/AIDS)
             o de     Suite
             Caroli   200
             na del   Columbi
             Sur      a, SC
                      29203
------------------------------------------------------------------------
Monetary    ADAP     312 11th          $5,000     6/1/2016  Improving
             Advoca   Avenue,                                Access to
             cy       #21g                                   Care Among
                      New                                    Transgender
                      York,                                  Men and
                      NY                                     Women
                      10001                                  Living with
                                                             HIV/AIDS
                                                             under the
                                                             AIDS Drug
                                                             Assistance
                                                             Program
                                                             (ADAP)
------------------------------------------------------------------------
Monetary    ADAP     312 11th          $5,000    2/29/2016  ADAP
             Advoca   Avenue,                                Directory
             cy       #21g
                      New
                      York,
                      NY
                      10001
------------------------------------------------------------------------
Monetary    African- 1833 W.         $200,000    12/6/2016  Certificatio
             Americ   8th                                    n of the
             an       St.,                                   U.S. HIV
             Aids     Suite                                  Workforce:
             Policy   200 Los                                A Project
             And      Angeles                                to Increase
             Traini   , CA                                   HIV
             ng       90057                                  Literacy
             Instit                                          and
             ute                                             Competency
------------------------------------------------------------------------
Monetary    AIDS     600 St.          $26,700    8/24/2016  (RFA)--Healt
             Action   Clair                                  hy Start
             Coalit   Avenue
             ion of   P.O.
             Huntsv   Box
             ille     2409
                      Huntsvi
                      lle, AL
                      35801
------------------------------------------------------------------------
Monetary    AIDS     75 Amory         $30,000    12/6/2016  Getting to
             Action   Street                                 Zero MA
             Commit   Boston,
             tee of   MA
             Massac   02119
             husett
             s
------------------------------------------------------------------------
Monetary    Aids     575 8th          $15,000    7/13/2016  HIV Health
             Commun   Ave,                                   Literacy
             ity      Suite                                  Education
             Resear   502 New                                and
             ch       York,                                  Training
             Initia   NY                                     for Service
             tive     10018                                  Providers
             of                                              Working
             Americ                                          with
             a                                               Vulnerable
             ACRIA                                           Populations
------------------------------------------------------------------------
Monetary    AIDS     200 W.           $48,000    6/21/2016  Ensuring
             Founda   Jackson                                Access to
             tion     Blvd                                   HIV
             of       Suite                                  Prevention
             Chicag   2100                                   and Care in
             o        Chicago                                Illinois
                      , IL                                   through
                      60606                                  Policy
                                                             Monitoring
                                                             and
                                                             Advocacy
------------------------------------------------------------------------
Monetary    AIDS     400 N             $5,000    2/29/2016  HIV Case
             Outrea   Beach                                  Management
             ch       Street                                 at AIDS
             Center   Fort                                   Outreach
                      Worth,                                 Center
                      TX
                      76111
------------------------------------------------------------------------
Monetary    AIDS     The               $7,500   12/14/2016  HIV Access
             Projec   David                                  and Care
             t Los    Geffen                                 Coordinatio
             Angele   Center                                 n Program
             s        611 S.
                      Kingsle
                      y Dr.
                      Los
                      Angeles
                      , CA
                      90005
------------------------------------------------------------------------
Monetary    AIDS     64 West          $20,000    6/21/2016  Peer
             Servic   35th                                   Education,
             e        Street,                                Health
             Center   3rd                                    Coaching,
             NYC      Floor                                  and Access
                      New                                    to Care
                      York,                                  programs
                      NY
                      10001
------------------------------------------------------------------------
Monetary    AIDS     P.O. Box         $30,000    8/24/2016  (RFA)--Posit
             Servic   169 121                                ive Living
             es       College
             Coalit   Street
             ion      Hatties
                      burg,
                      MS
                      39401
------------------------------------------------------------------------
Monetary    AIDS     17982             $5,000   12/16/2016  HIV and
             Servic   Sky                                    Hepatitis C
             es       Park                                   Testing
             Founda   Circle,                                Program
             tion     Suite J
             Orange   Irvine,
             County   CA
                      92614
------------------------------------------------------------------------
Monetary    AIDS     17982             $5,000    2/29/2016  HIV and
             Servic   Sky                                    Hepatitis C
             es       Park                                   Testing
             Founda   Circle,                                Program
             tion     Suite J
             Orange   Irvine,
             County   CA
                      92614
------------------------------------------------------------------------
Monetary    AIDS     7215              $5,000    1/18/2016  HIV Case
             Servic   Cameron                                Management
             es of    Road
             Austin   Austin,
             Inc.     TX
                      78752
------------------------------------------------------------------------
Monetary    AIDS     7215              $2,500   12/14/2016  Palateria
             Servic   Cameron                                Cart
             es of    Road
             Austin   Austin,
             Inc.     TX
                      78752
------------------------------------------------------------------------
Monetary    AIDS     7215             $30,000     8/8/2016  (RFA)--Risin
             Servic   Cameron                                g Star
             es of    Road                                   University
             Austin   Austin,
             Inc.     TX
                      78752
------------------------------------------------------------------------
Monetary    AIDS     1424 K          $300,000   12/19/2016  Transgender
             United   Street,                                Leadership
                      NW                                     Demonstrati
                      Suite                                  on Project
                      200
                      Washing
                      ton, DC
                      20005-2
                      411
------------------------------------------------------------------------
Monetary    Alexian  825 W.            $5,000    6/20/2016  Transitional
             Brothe   Welling                                Living
             rs       ton                                    Program for
             Bonave   Chicago                                Homeless
             nture    , IL                                   Adults with
             House    60657                                  HIV/AIDS
------------------------------------------------------------------------
Monetary    Allianc  825               $3,000   12/14/2016  Continuum-of-
             e For    Colorad                                Care
             Housin   o                                      Services
             g And    Blvd.,                                 for Multi-
             Healin   Suite                                  Diagnosed
             g        100 Los                                Persons
                      Angeles                                with HIV/
                      , CA                                   AIDS
                      90041
------------------------------------------------------------------------
Monetary    America  Greater           $3,000    8/25/2016  Ask the
             n        New                                    Experts:
             Liver    York                                   Hepatitis C/
             Founda   Divisio                                HIV Co-
             tion     n 39                                   infection
                      Broadwa                                Seminar
                      y Suite
                      2700
                      New
                      York,
                      NY
                      10006
------------------------------------------------------------------------
Monetary    Atlanta  P.O. Box         $15,000    2/16/2016  Hepatitis C
             Harm     92670                                  Prevention
             Reduct   Atlanta                                Program
             ion      , GA
             Coalit   30314
             ion
------------------------------------------------------------------------
Monetary    Bienest  5326 E           $25,000    12/6/2016  Bienestar
             ar       Beverly                                HIV
                      Blvd                                   Programs
                      Los                                    and
                      Angeles                                Services
                      , CA
                      90022
------------------------------------------------------------------------
Monetary    Brother  2714             $28,500    8/24/2016  (RFA)--EMPOW
             hood,    Canal                                  ER NOLA
             Inc.     Street
                      Suite
                      503A
                      New
                      Orleans
                      , LA
                      70119
------------------------------------------------------------------------
Monetary    Caring   PO Box           $40,000    3/24/2016  Hepatitis C
             Ambass   1748                                   Program
             adors    Oregon                                 Support--SH
             Progra   City,                                  APE and
             m Inc.   OR                                     CHOICES
                      97045
------------------------------------------------------------------------
Monetary    Catholi  119               $5,000    3/14/2016  The Home
             c        Dameron                                Place
             Charit   Avenue
             ies of   Knoxvil
             East     le, TN
             Tennes   37917
             see
             Inc.
------------------------------------------------------------------------
Monetary    Central  1785              $5,000    2/29/2016  Free On-Site
             Louisi   Jackson                                Neighborhoo
             ana      Street                                 d Testing,
             Aids     Alexand                                Counseling,
             Suppor   ria, LA                                and
             t        71301                                  Prevention
             Servic                                          Program
             es
             Inc.
             (CLASS
             )
------------------------------------------------------------------------
Monetary    Christi  2440             $10,000    7/13/2016  Integrated
             e's      Third                                  Services
             Place    Ave San                                for Women,
             Inc.     Diego,                                 Children
                      CA                                     and
                      92101                                  Families
------------------------------------------------------------------------
Monetary    Christi  2440             $20,000    2/18/2016  CHANGE for
             e's      Third                                  Women
             Place    Ave San
             Inc.     Diego,
                      CA
                      92101
------------------------------------------------------------------------
Monetary    Coaliti  127 W            $50,000    12/6/2016  Strengthenin
             on On    127th                                  g Patient
             Positi   Street                                 Education
             ve       Suite                                  through
             Health   208 New                                Technology
             Empowe   York,                                  and Social
             rment    NY                                     Media
             Inc.     10027
------------------------------------------------------------------------
Monetary    Coastal  5633             $15,000    10/7/2016  HEP:
             Bend     South                                  Hepatitis
             Wellne   Staples                                Education
             ss       , Suite                                Program
             Founda   700
             tion     Corpus
                      Christi
                      , TX
                      78411
------------------------------------------------------------------------
Monetary    Communi  714 East          $5,000    6/24/2016  Patient
             ty       Sahara                                 Wellness
             Counse   Ave.                                   Education
             ling     Suite
             Center   103 Las
                      Vegas,
                      NV
                      89104
------------------------------------------------------------------------
Monetary    Communi  2409             $29,633    8/24/2016  (RFA)--Safe
             ty       Murchis                                Spaces
             Health   on Rd                                  Ambassador
             Interv   Fayette                                Program
             ention   ville,
             s and    NC
             Sickle   28301
             Cell
             Agency
             Incorp
             orated
------------------------------------------------------------------------
Monetary    Communi  60               $30,000    2/29/2016  Transgender
             ty       Madison                                Linkage to
             Health   Avenue,                                Care
             care     5th
             Networ   floor
             k        New
                      York,
                      NY
                      10010
------------------------------------------------------------------------
Monetary    Compreh  142 S.           $25,000    8/24/2016  (RFA)--Proje
             ensive   Brunswi                                ct IRIS
             Aids     ck                                     (Improving
             Resour   Street                                 Retention
             ce       Suite B                                In the
             Encoun   P.O.                                   South)
             ter      Box 552
             Inc.     Jesup,
                      GA
                      31545
------------------------------------------------------------------------
Monetary    Crisis   1218                 $75    7/12/2016  Employee
             Shelte   West                                   directed
             r of     State                                  donation in
             Lawren   Street                                 lieu of
             ce       New                                    company
             County   Castle,                                holiday
                      PA                                     gift
                      16101-
                      2021
------------------------------------------------------------------------
Monetary    Desert   1695 N.           $5,000     6/1/2016  Get Tested
             AIDS     Sunrise                                Coachella
             Projec   Way                                    Valley
             t        Palm                                   Linkage to
                      Springs                                Care for
                      , CA                                   Newly
                      92262                                  Diagnosed
                                                             HIV-
                                                             Positive
                                                             Persons
------------------------------------------------------------------------
Monetary    Frannie  30                $5,000    9/13/2016  Integrated
             Peabod   Danfort                                Access to
             y        h St.                                  Care for
             Center   Suite                                  People
             Inc.     311                                    Living with
                      Portlan                                HIV/AIDS
                      d, ME
                      04101
------------------------------------------------------------------------
Monetary    Harm     22 West          $25,000    7/13/2016  Hepatitis C
             Reduct   27th                                   Project
             ion      Street
             Coalit   5th
             ion      Floor
                      New
                      York,
                      NY
                      10001
------------------------------------------------------------------------
Monetary    Health   1211              $5,000   12/14/2016  Pennsylvania
             Federa   Chestnu                                Ryan White
             tion     t                                      Part C/D
             Of       Street,                                Collaborati
             Philad   Suite                                  ve
             elphia   801
                      Philade
                      lphia,
                      PA
                      19107
------------------------------------------------------------------------
Monetary    HealthH  2000 S           $30,000    2/18/2016  Do You Know
             IV       Street                                 Me?:
                      NW                                     Engaging
                      Washing                                and
                      ton, DC                                Retaining
                      20009                                  Young MSM
                                                             of Color in
                                                             HIV Care
------------------------------------------------------------------------
Monetary    Heart    3600              $5,000    3/16/2016  BROTHA--Brot
             Health   Broadwa                                hers
             and      y West                                 Responding
             Healin   Palm                                   Openly to
             g        Beach,                                 HIV/AIDS
             Minist   FL                                     (Ujima
             ries     33407                                  Men's
             Inc.                                            Collective)
------------------------------------------------------------------------
Monetary    Hepatit  35 East          $22,000    2/18/2016  The
             is C     38th                                   Hepatitis C
             Mentor   Street,                                Education
             And      Suite                                  and Support
             Suppor   #4G New                                Group
             t        York,                                  Assistance
             Group    NY                                     Program
             Inc.     10016
------------------------------------------------------------------------
Monetary    Hepatit  1261 S.          $35,000    3/14/2016  Case
             is       Jackson                                management
             Educat   St.                                    ($25,000);
             ion      Suite                                  King County
             Projec   201                                    Jail
             t        Seattle                                Hepatitis
                      , WA                                   Education
                      98144                                  ($10,000)
------------------------------------------------------------------------
Monetary    Hepatit  8121              $5,000     5/6/2016  Call To
             is       Georgia                                Action: A
             Founda   Avenue                                 National
             tion     Suite                                  Response
             Intern   350                                    for
             ationa   Silver                                 Hepatitis C
             l Inc.   Spring,                                Treatment
                      MD                                     among the
                      20910                                  Hard to
                                                             Reach, Hard
                                                             to Treat.
                                                             Proposal
------------------------------------------------------------------------
Monetary    Jackson  P.O. Box         $30,000     8/8/2016  (RFA)--#AIDS
             ville    380103                                 FreeJax
             Area     Jackson                                Linkage to
             Sexual   ville,                                 Care (L2C)
             Minori   FL                                     Program--a
             ty       32205                                  Comprehensi
             Youth                                           ve HIV/AIDS
             Networ                                          Linkage to
             k,                                              Care
             Inc.                                            Program for
             (JASMY                                          African
             N)                                              American
                                                             YMSM, ages
                                                             13-23
------------------------------------------------------------------------
Monetary    Legacy   4054              $5,000   12/14/2016  Legacy
             Counse   McKinne                                Counseling
             ling     y                                      Center
             Center   Avenue                                 Counseling
                      Suite                                  and Walk-In
                      102                                    Crisis
                      Dallas,                                Clinic
                      TX                                     Program for
                      75204                                  People
                                                             Living with
                                                             HIV/AIDS
------------------------------------------------------------------------
Monetary    Make-A-  2880                $450     2/8/2016  Employee
             Wish     Slater                                 directed
             Founda   Road,                                  donation in
             tion     Suite                                  lieu of
             of       108                                    company
             Easter   Morrisv                                holiday
             n        ille,                                  gift
             North    NC
             Caroli   27560
             na
------------------------------------------------------------------------
Monetary    MCCNY    446 West         $10,000    12/6/2016  Linkage to
             Charit   36th                                   Care for
             ies      Street                                 LGBTQI
                      New                                    Homeless
                      York,                                  Youth
                      NY
                      10018
------------------------------------------------------------------------
Monetary    Minorit  5149 W.           $7,500    4/12/2016  The Missing
             y AIDS   Jeffers                                Link
             Projec   on Blvd                                ``G.L.A.M.O
             t        Los                                    .R.''
                      Angeles                                (Getting
                      , CA                                   Linked And
                      90016                                  Managing
                                                             Our
                                                             Regimen)
------------------------------------------------------------------------
Monetary    Missour  601               $9,650     8/9/2016  Hep C
             i        Busines                                Education
             Hepati   s Loop                                 and
             tis C    70 West                                Testing--Th
             Allian   Suite                                  e Texas
             ce       138                                    Project
                      Columbi
                      a, MO
                      65203
------------------------------------------------------------------------
Monetary    Nationa  580             $175,000     3/7/2016  NATAP HIV
             l AIDS   Broadwa                                and HCV
             Treatm   y Suite                                Information
             ent      1010                                   and
             Advoca   New                                    Education
             cy       York,                                  Project
             Projec   NY
             t        10012
------------------------------------------------------------------------
Monetary    Nationa  444 N.          $150,000   12/19/2016  Health
             l        Capitol                                Systems
             Allian   St., NW                                Integration
             ce of    Suite                                  , Ryan
             State    339                                    White/ADAP,
             and      Washing                                and Viral
             Territ   ton, DC                                Hepatitis
             orial    20001                                  Public
             AIDS                                            Policy and
             Direct                                          Technical
             ors                                             Assistance
                                                             Programs
------------------------------------------------------------------------
Monetary    Nationa  1000             $50,000   12/15/2016  Strong
             l        Vermont                                Communities
             Minori   Avenue                                 : Social
             ty       NW                                     Drivers of
             AIDS     Suite                                  HIV
             Counci   200
             l        Washing
                      ton, DC
                      20005
------------------------------------------------------------------------
Monetary    Nationa  1000             $30,000    2/16/2016  Strong
             l        Vermont                                Communities
             Minori   Avenue                                 :
             ty       NW                                     Strengtheni
             AIDS     Suite                                  ng
             Counci   200                                    connections
             l        Washing                                between
                      ton, DC                                LGBT
                      20005                                  communities
                                                             of color
                                                             and the
                                                             providers
                                                             that serve
                                                             them
------------------------------------------------------------------------
Monetary    New      44 South          $5,000    2/29/2016  Community
             Jersey   Street                                 Based
             AIDS     Morrist                                Services
             Servic   own, NJ
             es       07960
------------------------------------------------------------------------
Monetary    Next     99                $5,000    6/20/2016  Expansion of
             Step     Bishop                                 Next Step's
             Fund     Allen                                  Year-round
             Inc.     Drive                                  Programming
                      Cambrid                                for teens
                      ge, MA                                 and young
                      02139                                  adults
                                                             living with
                                                             HIV.
------------------------------------------------------------------------
Monetary    Our      2727 SE           $5,000    8/23/2016  Neighborhood
             House    Alder                                  Housing and
             of       St.                                    Care
             Portla   Portlan                                Program
             nd       d, OR                                  (NHCP)
             Incorp   97214
             orated
------------------------------------------------------------------------
Monetary    Palmett  2638 Two          $7,500     5/6/2016  HIV Care
             o AIDS   Notch                                  Coordinatio
             Life     Road,                                  n Program
             Suppor   Suite
             t        108
             Servic   Columbi
             es       a, SC
                      29204
------------------------------------------------------------------------
Monetary    Positiv  785               $2,500   12/16/2016  Employment
             e        Market                                 and
             Resour   Street,                                Benefits
             ce       10th                                   Education
             Center   Floor
                      San
                      Francis
                      co, CA
                      94103
------------------------------------------------------------------------
Monetary    Project  273              $60,000    10/6/2016  Policy
             Inform   Ninth                                  Initiatives
                      Street                                 to Improve
                      San                                    Access to
                      Francis                                Care and
                      co, CA                                 Treatment
                      94103
------------------------------------------------------------------------
Monetary    Project  273              $20,000    7/15/2016  Hepatitis C
             Inform   Ninth                                  Education
                      Street                                 and Linkage
                      San                                    to Care
                      Francis
                      co, CA
                      94103
------------------------------------------------------------------------
Monetary    Project  273              $30,000   12/19/2016  The Support
             Inform   Ninth                                  Partnership
                      Street
                      San
                      Francis
                      co, CA
                      94103
------------------------------------------------------------------------
Monetary    Project  273              $70,000    5/19/2016  Mission
             Inform   Ninth                                  Support for
                      Street                                 Project
                      San                                    Inform
                      Francis
                      co, CA
                      94103
------------------------------------------------------------------------
Monetary    Project  273              $40,000    2/18/2016  The Support
             Inform   Ninth                                  Partnership
                      Street
                      San
                      Francis
                      co, CA
                      94103
------------------------------------------------------------------------
Monetary    RAIN,    601 E.           $30,000     8/8/2016  (RFA)--Impro
             Inc.     5th                                    ving
                      Street,                                Retention
                      Suite                                  in Care and
                      470                                    Access to
                      Charlot                                Treatment
                      te, NC                                 for African
                      28202                                  Americans
                                                             Living with
                                                             HIV in
                                                             Charlotte
                                                             Metropolita
                                                             n area
------------------------------------------------------------------------
Monetary    RAIN,    601 E.            $5,000    4/25/2016  Medical Case
             Inc.     5th                                    Management
                      Street,                                for Youth,
                      Suite                                  Adults and
                      470                                    Seniors
                      Charlot                                with HIV/
                      te, NC                                 AIDS
                      28202
------------------------------------------------------------------------
Monetary    Recover  3423             $75,000    4/15/2016  The Healthy
             y        Covingt                                Start
             Consul   on                                     Program
             tants    Drive,
             Of       Suite B
             Atlant   Decatur
             a        , GA
             Incorp   30032
             orated
------------------------------------------------------------------------
Monetary    Resourc  5750              $3,000   12/14/2016  Valor Latino
             e        Cedar                                  Project
             Center   Springs
             of       Road
             Dallas   Dallas,
             , Inc.   TX
                      75235-6
                      805
------------------------------------------------------------------------
Monetary    Sero     PO Box           $15,000    2/29/2016  HIV is Not a
             Projec   1233                                   Crime
             t Inc.   Milford                                regional
                      , PA                                   and
                      18337                                  national
                                                             conferences
                                                             and webinar
                                                             trainings
------------------------------------------------------------------------
Monetary    Shanti   730 Polk         $10,000    7/13/2016  Shanti HIV
             Projec   Street,                                Services
             t Inc.   3rd                                    Program/HCV
                      Floor                                  Services
                      San
                      Francis
                      co, CA
                      94109
------------------------------------------------------------------------
Monetary    South    601               $7,500    6/27/2016  West
             Centra   Bland                                  Virginia
             l        Street                                 Infection
             Educat   P.O.                                   Disease
             ional    Box                                    Coalition
             Develo   4322
             pment    Bluefie
                      ld, WV
                      24701
------------------------------------------------------------------------
Monetary    Southwe  1101 N.           $5,000   12/14/2016  General
             st       Central                                mission
             Center   Avenue                                 support
             For      Suite
             HIV/     200
             AIDS     Phoenix
             Inc.     , AZ
                      85004
------------------------------------------------------------------------
Monetary    Step-Up  850 N.            $5,000   12/16/2016  Indianapolis
             Incorp   Meridia                                Men
             orated   n                                      Advancing
                      Street                                 Prevention
                      First                                  (IMAP)
                      Floor
                      Indiana
                      polis,
                      IN
                      46204
------------------------------------------------------------------------
Monetary    The      17 Davis         $65,000    12/6/2016  Ensuring
             Aids     Blvd.                                  Adequate
             Instit   Suite                                  Funding for
             ute      403                                    Domestic
                      Tampa,                                 HIV/AIDS
                      FL                                     and
                      33606                                  Hepatitis
                                                             Programs
------------------------------------------------------------------------
Monetary    The      429 E.               $75     2/8/2016  Employee
             Health   Vermont                                directed
             Founda   Street,                                donation in
             tion     Suite                                  lieu of
             of       400                                    company
             Greate   Indiana                                holiday
             r        polis,                                 gift
             Indian   IN
             apolis   46202
------------------------------------------------------------------------
Monetary    The Hep  1325 S.          $15,000    7/12/2016  HCV Patient
             C        Colorad                                Linkage to
             Connec   o                                      Care and
             tion     Blvd.,                                 Navigation
                      B-302
                      Denver,
                      CO
                      80222
------------------------------------------------------------------------
Monetary    The      PO Box           $30,000    8/24/2016  (RFA)--``Rep
             Open     99243                                  ''
             Door,    Pittsbu                                presenting
             Inc.     rgh, PA                                the
                      15233                                  solution
                                                             for optimal
                                                             health
                                                             outcomes
                                                             and housing
                                                             stability
                                                             for African
                                                             American
                                                             ``payees''
                                                             living with
                                                             HIV/AIDS
------------------------------------------------------------------------
Monetary    The San  3909              $5,000     3/7/2016  Latin@
             Diego    Centre                                 Services
             LGBT     St San                                 program
             Commun   Diego,
             ity      CA
             Center   92103
------------------------------------------------------------------------
Monetary    The      85               $30,000    3/24/2016  Support
             Well     Norman                                 Information
             Projec   Avenue,                                ,
             t        Suite 1                                Community,
                      P.O.                                   Advocacy
                      Box                                    and
                      220410                                 Evaluation
                      Brookly
                      n, NY
                      11222
------------------------------------------------------------------------
Monetary    The      1331             $30,000    8/24/2016  (RFA)--Enhan
             Women'   Rhode                                  cements of
             s        Island                                 Community
             Collec   Avenue                                 Health
             tive     NE                                     Worker
                      Washing                                Program
                      ton, DC
                      20018
------------------------------------------------------------------------
Monetary    Tourett  4240                 $75     5/4/2016  Donation in
             e        Bell                                   lieu of
             Associ   Blvd.,                                 company
             ation    Suite                                  holiday
             of       205                                    gift
             Americ   Bayside
             a        , NY
                      11361
------------------------------------------------------------------------
Monetary    TPA      5050 N.           $5,000     6/1/2016  Healthy
             Networ   Broadwa                                Aging with
             k        y Suite                                HIV
             Incorp   300
             orated   Chicago
             Test     , IL
             Positi   60640
             ve
             Aware
             Networ
             k
------------------------------------------------------------------------
Monetary    TPA      5050 N.          $25,000    10/6/2016  Total Care
             Networ   Broadwa                                Portal
             k        y Suite
             Incorp   300
             orated   Chicago
             Test     , IL
             Positi   60640
             ve
             Aware
             Networ
             k
------------------------------------------------------------------------
Monetary    Treatme  261              $25,000    5/19/2016  Case Studies
             nt       Fifth
             Action   Ave
             Group,   Suite
             Inc.     2110
                      New
                      York,
                      NY
                      10016
------------------------------------------------------------------------
Monetary    Univers  UCSF              $7,500    6/20/2016  Mission-
             ity of   Allianc                                Based
             Califo   e                                      Support of
             rnia     Health                                 UCSF
             San      Project                                Alliance
             Franci   1855                                   Health
             sco      Folsom                                 Project
                      Street,                                Services
                      Ste.                                   for People
                      670 Box                                Living With
                      0884                                   or at Risk
                      San                                    of HIV/AIDS
                      Francis
                      co, CA
                      94143
------------------------------------------------------------------------
Monetary    Univers  5801 S.          $20,741     3/7/2016  4 Her by Her
             ity of   Ellis
             Chicag   Avenue
             o        Chicago
                      , IL
                      60637
------------------------------------------------------------------------
Monetary    US       1300 PA         $500,000     8/5/2016  Bedaquiline
             Agency   Avenue.                                Donation
             for      , NW SA-                               Program in
             Intern   44 Rm                                  support of
             ationa   475-J                                  World
             l        Washing                                Health
             Develo   ton, DC                                Organizatio
             pment    20523                                  n's END TB
                                                             Strategy
                                                             for 2016-
                                                             2035
------------------------------------------------------------------------
Monetary    Venice   604 Rose          $5,000   12/16/2016  Venice
             Family   Ave.                                   Family
             Clinic   Venice,                                Clinic's
                      CA                                     Common
                      90291                                  Ground
------------------------------------------------------------------------
Monetary    Vermont  187               $5,000     6/1/2016  Vermont HIV
             Commit   Saint                                  Transportat
             tee      Paul                                   ion Support
             For      Street
             Aids     Burling
             Resour   ton, VT
             ces      05401
             Educat
             ion
             and
             Servic
             es
------------------------------------------------------------------------
Monetary    Washing  566 West         $30,000    3/24/2016  Engaging
             ton      181st                                  High Risk
             Height   Street,                                Active
             s        Floor 2                                Injection
             CORNER   New                                    Drug Users
             Projec   York,                                  in
             t        NY                                     Hepatitis C
                      10033                                  Testing and
                                                             Treatment
                                                             in Northern
                                                             Manhattan
------------------------------------------------------------------------
Monetary    Women    417               $7,500    4/25/2016  SafetyPIN
             On       Welshwo
             Mainta   od
             ining    Drive,
             Educat   Suite
             ion      303
             And      Nashvil
             Nutrit   le, TN
             ion      37211-
                      4248
------------------------------------------------------------------------
Monetary    Womens   4615              $2,500    3/23/2016  She's Still
             Challe   Harrier                                Got It
             nge      Way                                    educational
             Inc.     Belcamp                                initiative
                      , MD
                      21017
------------------------------------------------------------------------
Monetary    WORLD    389 30th         $15,000   12/14/2016  Community
             Women    St                                     Researchers
             Organi   Oakland                                Engaging
             zed to   , CA                                   Women
             Respon   94609                                  (CREW) III
             d to
             Life-
             threat
             ening
             Diseas
             es
------------------------------------------------------------------------


----------------------------------------------------------------------------------------------------------------
 
----------------------------------------------------------------------------------------------------------------
Product               Johnson & Johnson     One Johnson &          $ 3,700,026    3/31/2016  Patient Assistance
                       Patient Assistance    Johnson Plaza New                                Product Donation
                       Foundation            Brunswick, NJ 08933
----------------------------------------------------------------------------------------------------------------
Product               Johnson & Johnson     One Johnson &          $ 3,459,402    6/30/2016  Patient Assistance
                       Patient Assistance    Johnson Plaza New                                Product Donation
                       Foundation            Brunswick, NJ 08934
----------------------------------------------------------------------------------------------------------------
Product               Johnson & Johnson     One Johnson &          $ 2,280,117    9/30/2016  Patient Assistance
                       Patient Assistance    Johnson Plaza New                                Product Donation
                       Foundation            Brunswick, NJ 08935
----------------------------------------------------------------------------------------------------------------
Product               Johnson & Johnson     One Johnson &          $ 3,874,808   12/31/2016  Patient Assistance
                       Patient Assistance    Johnson Plaza New                                Product Donation
                       Foundation            Brunswick, NJ 08936
----------------------------------------------------------------------------------------------------------------
Product               Partnership for       1616 Fort Myer         $ 6,123,407    10/3/2016  Product donation
                       Supply Chain          Drive, 12th Floor                                for humanitarian
                       Management            Arlington, VA 22209-                             assistance.
                                             3100
----------------------------------------------------------------------------------------------------------------
Product               US Agency for         1300 PA Avenue., NW,  $ 44,580,000    12/1/2016  Bedaquiline product
                       International         SA-44 Rm 475-J                                   donation
                       Development           Washington, DC
                                             20523
----------------------------------------------------------------------------------------------------------------
Updated March 30, 2018


  Janssen Biotech, Inc. Monetary and Product Contribution to U.S.-based
                 Charitable Organizations Full Year 2017
        (Payments made from January 1, 2017 to December 31, 2017)
------------------------------------------------------------------------
                                                               Project
 Donation    Payee     Payee   Payment Amount    Payment       Title/
   Type               Address       (USD)          Date      Description
------------------------------------------------------------------------
Monetary    AAUW     7511              $1,000   12/14/2017  Annual
             Makefi   Germant                                Girl's
             eld      own                                    Recognition
             Area     Avenue                                 Reception
             Branch   Philade                                and
             PA       lphia,                                 Scholarship
             Inc.     PA                                     Awards
                      19119                                  American
                                                             Association
                                                             of
                                                             University
                                                             Women--Make
                                                             field
                                                             Branch
------------------------------------------------------------------------
Monetary    Aid For  12271               $300   11/16/2017  Costs
             Friend   Townsen                                associated
             s        d Rd.                                  with
                      Philade                                Janssen
                      lphia,                                 Cares
                      PA                                     Volunteer
                      19154                                  Activity--S
                                                             eptember
                                                             27, 2017
------------------------------------------------------------------------
Monetary    Aid For  12271               $300   11/16/2017  Costs
             Friend   Townsen                                associated
             s        d Rd.                                  with
                      Philade                                Janssen
                      lphia,                                 Cares
                      PA                                     Volunteer
                      19154                                  Activity--O
                                                             ctober 6,
                                                             2017
------------------------------------------------------------------------
Monetary    America  250               $9,500     2/2/2017  General
             n        William                                Operating
             Cancer   s                                      Support
             Societ   Street
             y        NW
             (HDQTS   Atlanta
             )        , GA
                      30303
------------------------------------------------------------------------
Monetary    America  Atlanta             $300   10/25/2017  Costs
             n        Hope                                   associated
             Cancer   Lodge                                  with
             Societ   1552                                   Janssen
             y Inc.   Shoup                                  Cares
                      Ct                                     Volunteer
                      Decatur                                Activity
                      , GA
                      30033
------------------------------------------------------------------------
Monetary    America  1626              $1,000    4/21/2017  Relay For
             n        Locust                                 Life of the
             Cancer   Street                                 Wissahickon
             Societ   Philade                                Valley
             y Inc,   lphia,
             Philad   PA
             elphia   19103
             , PA
------------------------------------------------------------------------
Monetary    Arthrit  1355            $200,000    5/24/2017  Walk To Cure
             is       Peachtr                                Arthritis
             Founda   ee                                     and Jingle
             tion     Street,                                Bell Run
                      Suite
                      600
                      Atlanta
                      , GA
                      30309
------------------------------------------------------------------------
Monetary    Arthrit  1355            $200,000   12/21/2017  Walk To Cure
             is       Peachtr                                Arthritis
             Founda   ee                                     and Jingle
             tion     Street,                                Bell Run
                      Suite
                      600
                      Atlanta
                      , GA
                      30309
------------------------------------------------------------------------
Monetary    Artz     1229              $7,500   11/30/2017  ``ARTZ in
             Philad   Chestnu                                the
             elphia   t                                      Neighborhoo
                      Street,                                d: A
                      #188                                   Community-
                      Philade                                Based
                      lphia,                                 Program''
                      PA
                      19107
------------------------------------------------------------------------
Monetary    Breathi  600 West          $5,000   12/25/2017  Program and
             ng       Avenue,                                Family
             Room     P.O.                                   Services--B
             Founda   Box 287                                reathing
             tion     Jenkint                                Room
                      own, PA                                Foundation
                      19046-2
                      729
------------------------------------------------------------------------
Monetary    Cancer   3                 $5,000    3/30/2017  Oncology
             Suppor   Crossro                                Support
             t        ads                                    Groups
             Commun   Drive
             ity      Bedmins
             Centra   ter, NJ
             l New    07921
             Jersey
------------------------------------------------------------------------
Monetary    Cancer   1200 Old          $5,000    5/19/2017  Voice of the
             Suppor   Henders                                Patient:
             t        on                                     Distress
             Commun   Columbu                                Screening
             ity      s, OH                                  and Support
             Centra   43220                                  for Cancer
             l Ohio                                          Patients
                                                             and
                                                             Survivors
------------------------------------------------------------------------
Monetary    Cancer   200 Kirk          $2,000    7/31/2017  Paws 4 Life
             Suppor   Road                                   Dog Walk
             t        Warmins
             Commun   ter, PA
             ity of   18974
             Philad
             elphia
------------------------------------------------------------------------
Monetary    Cancer   200 Kirk            $300   11/30/2017  Costs
             Suppor   Road                                   associated
             t        Warmins                                with
             Commun   ter, PA                                Janssen
             ity of   18974                                  Cares
             Philad                                          Volunteer
             elphia                                          Activity--S
                                                             eptember 28
                                                             2017
------------------------------------------------------------------------
Monetary    Cancer   200 Kirk            $300   11/30/2017  Costs
             Suppor   Road                                   associated
             t        Warmins                                with
             Commun   ter, PA                                Janssen
             ity of   18974                                  Cares
             Philad                                          Volunteer
             elphia                                          Activity--S
                                                             eptember 28
                                                             2017
------------------------------------------------------------------------
Monetary    Center   1617              $5,000     9/4/2017  Project for
             for      John F.                                Medically
             Child    Kennedy                                Needy
             Advoca   Bouleva                                Children
             tes      rd
                      Philade
                      lphia,
                      PA
                      19103
------------------------------------------------------------------------
Monetary    Central  2500                $300   11/30/2017  Costs
             Bucks    Lower                                  associated
             Family   State                                  with
             YMCA     Road                                   Janssen
                      Doylest                                Cares
                      own, PA                                Volunteer
                      18901                                  Activity--O
                                                             ctober 3
                                                             2017
------------------------------------------------------------------------
Monetary    Chester  100               $5,000    12/1/2017  Outreach
             County   North                                  Programs
             Art      Bradfor
             Associ   d
             ation    Avenue
                      West
                      Chester
                      , PA
                      19382
------------------------------------------------------------------------
Monetary    Chester  790 East          $6,000   12/22/2017  Certified
             County   Market                                 Nurse
             Opport   Street,                                Assistant
             unitie   Suite                                  (CNA)
             s        100                                    Program
             Indust   West
             rializ   Chester
             ation    , PA
             Center   19382
------------------------------------------------------------------------
Monetary    Chestnu  1710              $2,500   11/30/2017  General
             t Hill   Bethleh                                Operating
             Meals    em Pike                                Support
             on       Flourto
             Wheels   wn, PA
                      19031
------------------------------------------------------------------------
Monetary    Childre  100 Penn         $12,000    6/28/2017  Family Care
             n's      Square                                 Binder
             Hospit   East                                   Program
             al of    8th
             Philad   Floor,
             elphia   Suite
             Founda   8050
             tion     Philade
                      lphia,
                      PA
                      19107
------------------------------------------------------------------------
Monetary    Childre  100 Penn          $6,000    4/13/2017  Walk for
             n's      Square                                 Hope
             Hospit   East                                   Benefiting
             al of    8th                                    Pediatric
             Philad   Floor,                                 Inflammator
             elphia   Suite                                  y Bowel
             Founda   8050                                   Disease
             tion     Philade                                Research at
                      lphia,                                 CHOP
                      PA
                      19107
------------------------------------------------------------------------
Monetary    Communi  300B             $25,000   12/21/2017  Provision of
             ty       Lawrenc                                free
             Volunt   e Drive                                medical and
             eers     West                                   dental
             in       Chester                                healthcare
             Medici   , PA                                   to the
             ne       19380                                  uninsured
                                                             in Chester
                                                             County
------------------------------------------------------------------------
Monetary    Crohn's  733 3rd          $18,000    6/13/2017  Camp Oasis
             and      Avenue
             Coliti   Suite
             s        510 New
             Founda   York,
             tion--   NY
             NY       10017
             Chapte
             r
------------------------------------------------------------------------
Monetary    Crohn's  733 3rd         $100,000   10/30/2017  Take Steps
             and      Avenue                                 for Crohn's
             Coliti   Suite                                  and Colitis
             s        510 New                                Walks
             Founda   York,
             tion--   NY
             NY       10017
             Chapte
             r
------------------------------------------------------------------------
Monetary    Delawar  236               $5,000    5/22/2017  Teacher
             e        Randell                                Development
             Valley   Hall                                   Program
             Scienc   3141
             e        Chestnu
             Fairs,   t
             Inc.     Street
                      Philade
                      lphia,
                      PA
                      19104
------------------------------------------------------------------------
Monetary    Emmanue  67                $3,500   12/21/2017  Pediatric
             l        Walnut                                 Cancer
             Cancer   Ave.                                   Family
             Founda   Suite                                  Financial
             tion     107                                    Assistance
                      Clark,                                 Fund
                      NJ
                      07040
------------------------------------------------------------------------
Monetary    Family   142             $250,000   12/15/2017  Family Reach
             Reach    Berkele                                Financial
             Founda   y                                      Assistance
             tion     Street;                                and
                      4th                                    Resource
                      Floor                                  Navigation
                      Boston,                                Programs
                      MA
                      02116
------------------------------------------------------------------------
Monetary    For      620 West          $1,000    5/15/2017  7th Annual
             Pete's   Germant                                For Pete's
             Sake     own                                    Sake, Walk!
             Cancer   Pike                                   at Citizens
             Respit   Suite                                  Bank Park
             e        250
             Founda   Plymout
             tion     h
                      Meeting
                      , PA
                      19462
------------------------------------------------------------------------
Monetary    Friends  113 West          $5,000   12/14/2017  Outreach to
             Associ   Chestnu                                Homeless
             ation    t                                      Families
             For      Street
             Care     West
             and      Chester
             Protec   , PA
             tion     19380
             Of
             Childr
             en
------------------------------------------------------------------------
Monetary    Georgia  560               $2,500    5/11/2017  Free
             Prosta   Barnesl                                Prostate
             te       ey Lane                                Cancer
             Cancer   Alphare                                Screening
             Coalit   tta, GA
             ion      30022
             Inc.
------------------------------------------------------------------------
Monetary    Girl     330               $4,000   11/21/2017  Science,
             Scouts   Manor                                  Technology,
             of       Road                                   Engineering
             Southe   Miquon,                                , and Math
             astern   PA                                     Outreach
             Pennsy   19444-1                                Programming
             lvania   741
------------------------------------------------------------------------
Monetary    Global   515 N.           $25,000   12/21/2017  Puerto Rico
             Health   Midland                                Rheumatolog
             y        Ave                                    y Relief
             Living   Upper
             Founda   Nyack,
             tion,    NY
             Inc.     10960
------------------------------------------------------------------------
Monetary    Habitat  1847 E            $2,500   12/18/2017  Cambria
             for      Lincoln                                Housing
             Humani   Hwy                                    Development
             ty of    Coatesv                                -providing
             Cheste   ille,                                  decent
             r        PA                                     affordable
             County   19320                                  housing
             , Inc.                                          options in
                                                             Chester
                                                             County Pa.
------------------------------------------------------------------------
Monetary    Habitat  1829 N.           $5,000   12/13/2017  Diamond Park
             For      19th
             Humani   Street
             ty       Philade
             Philad   lphia,
             elphia   PA
             Inc.     19121
------------------------------------------------------------------------
Monetary    Hatboro- 229              $25,000    12/1/2017  STEM
             Horsha   Meeting                                Programs
             m        house                                  for Hatboro-
             Educat   Road                                   Horsham
             ional    Horsham                                Students
             Founda   , PA
             tion     19044
------------------------------------------------------------------------
Monetary    Jack     3282             $25,000    5/31/2017  WOW!
             And      Northsi                                Experience
             Jill     de
             Late     Parkway
             Stage    , NW
             Cancer   Suite
             Founda   100
             tion     Atlanta
             Inc.     , GA
                      33327
------------------------------------------------------------------------
Monetary    Joy of   580                 $525    4/11/2017  Employee
             Sox      Lindsey                                directed
                      Dr.,                                   donation in
                      Ste 150                                lieu of
                      Radnor,                                company
                      PA                                     holiday
                      19087                                  gift
------------------------------------------------------------------------
Monetary    Kids     26071             $3,000   11/21/2017  Support
             Connec   Merit                                  Groups for
             ted      Circle,                                the
                      #103                                   Children of
                      Laguna                                 Cancer
                      Hills,                                 Patients
                      CA
                      92653-7
                      016
------------------------------------------------------------------------
Monetary    Lenape   500 N.             $ 300   11/30/2017  Costs
             Valley   West                                   associated
             Founda   Street                                 with
             tion     Doylest                                Janssen
                      own, PA                                Cares
                      18901                                  Volunteer
                                                             Activity--S
                                                             eptember 29
                                                             2017
------------------------------------------------------------------------
Monetary    Metropo  420 N            $30,000    12/1/2017  Medical
             litan    20th                                   Nutrition
             Area     Street                                 for People
             Neighb   Philade                                with Severe
             orhood   lphia,                                 Illnesses
             Nutrit   PA
             ion      19103
             Allian
             ce
             (MANNA
             )
------------------------------------------------------------------------
Monetary    Mitzvah  1561              $5,000   11/28/2017  Critical
             Circle   Gehman                                 Needs for
             Founda   Rd.                                    Families
             tion     Harleys                                and
                      ville,                                 Individuals
                      PA
                      19438
------------------------------------------------------------------------
Monetary    Montgom  340              $33,660   10/27/2017  Bridge to
             ery      Dekalb                                 Employment
             County   Pike                                   Extension--
             Commun   Blue                                   Wissahickon
             ity      Bell,                                  High School
             Colleg   PA
             e        19422
             Founda
             tion
------------------------------------------------------------------------
Monetary    NAMI of  100 W,            $2,500    10/4/2017  Mental
             PA       Main                                   health
             Montgo   St.                                    education,
             mery     Suite                                  support and
             County   204                                    advocacy
                      Lansdal                                programs as
                      e, PA                                  well as
                      19446                                  support of
                                                             Ending the
                                                             Silence
                                                             program
------------------------------------------------------------------------
Monetary    NAMI of  100 W,            $1,000   12/25/2017  NAMIWalks
             PA       Main                                   Greater
             Montgo   St.                                    Philadelphi
             mery     Suite                                  a
             County   204
                      Lansdal
                      e, PA
                      19446
------------------------------------------------------------------------
Monetary    Nationa  1107              $2,500    5/31/2017  National
             l        Lakevie                                Cancer
             Cancer   w Dr,                                  Survivors
             Surviv   Suite                                  Day 2017
             ors      C1
             Day      Frankli
             Founda   n, TN
             tion     37067
------------------------------------------------------------------------
Monetary    Nationa  4950              $2,500    7/31/2017  19th Annual
             l        York                                   Break the
             Ovaria   Rd,                                    Silence on
             n        Unit                                   Ovarian
             Cancer   631                                    Cancer Run/
             Coalit   Holicon                                Walk
             ion      g, PA
             Inc.     18928
------------------------------------------------------------------------
Monetary    Nationa  6600 SW          $50,000    3/16/2017  2017 Team
             l        92nd                                   NPF Walk
             Psoria   Ave.,
             sis      #300
             Founda   Portlan
             tion     d, OR
                      97223
------------------------------------------------------------------------
Monetary    Nationa  6600 SW          $20,000    12/5/2017  Patient
             l        92nd                            2017   Education
             Psoria   Ave.,                                  Initiative:
             sis      #300                                   Phase Three
             Founda   Portlan
             tion     d, OR
                      97223
------------------------------------------------------------------------
Monetary    North    P.O. Box          $5,000    12/4/2017  Project
             Penn     103 16                                 Learn
             Valley   Susqueh                                Homework
             Boys     anna                                   Program
             and      Avenue
             Girls    Lansdal
             Club     e, PA
             Inc.     19446
------------------------------------------------------------------------
Monetary    One      P.O. Box             $75    4/11/2017  Employee
             Days     18071                                  directed
             Wages    Seattle                                donation in
                      , WA                                   lieu of
                      98118                                  company
                                                             holiday
                                                             gift
------------------------------------------------------------------------
Monetary    Patient  700 12TH          $5,000    3/31/2017  Patients
             s        ST NW                                  Rising
             Rising   Ste.                                   University:
             Inc.     700                                    Spotlight
                      Washing                                Rheumatoid
                      ton, DC                                Arthritis
                      20005
------------------------------------------------------------------------
Monetary    Philade  325               $5,000    1/24/2017  Summer READS
             lphia    Chestnu
             Reads    t
                      Street-
                      -Suite
                      903
                      Philade
                      lphia,
                      PA
                      19106
------------------------------------------------------------------------
Monetary    Project  1515              $2,000   11/30/2017  Ending
             Home     Fairmou                                Homelessnes
                      nt                                     s in
                      Avenue                                 Philadelphi
                      Philade                                a Through
                      lphia,                                 Supportive
                      PA                                     Housing
                      19130
------------------------------------------------------------------------
Monetary    Prostat  7009 S.          $30,000     6/2/2017  Prostate
             e        Potomac                                Cancer
             Cancer   Street                                 Disparities
             Educat   Suite                                  Outreach
             ion      125                                    Program
             Counci   Centenn
             l        ial, CO
                      80112
------------------------------------------------------------------------
Monetary    Quest    461 Cann          $4,000    5/25/2017  Hippotherapy
             Therap   Rd.                                    (Equine-
             eutic    West                                   PAssisted
             Servic   Chester                                Therapy)
             es       , PA                                   Program
             Inc.     19382                                  Support to
                                                             Serve
                                                             Children
                                                             with
                                                             Special
                                                             Needs
------------------------------------------------------------------------
Monetary    Rebuild  4355              $5,000    3/22/2017  Belmont
             ing      Orchard                                Block Build
             Togeth   Street                                 2017
             er       Suite
             Philad   2R
             elphia   Philade
                      lphia,
                      PA
                      19124
------------------------------------------------------------------------
Monetary    Retired  901 East          $7,000    5/31/2017  RSVP's
             and      8th                                    America
             Senior   Street                                 Reads/
             Volunt   Suite                                  Writes and
             eer      200                                    Protege
             Progra   King of                                Programs
             m of     Prussia
             Montgo   , PA
             mery     19406
             County
------------------------------------------------------------------------
Monetary    Retired  901 East         $10,000   12/13/2017  RSVP's My
             and      8th                                    Free Tutor
             Senior   Street                                 (MFT)
             Volunt   Suite                                  Program and
             eer      200                                    Family
             Progra   King of                                Literacy
             m of     Prussia                                Volunteer
             Montgo   , PA                                   Program
             mery     19406                                  (FLVP)
             County
------------------------------------------------------------------------
Monetary    Riverbe  1950              $6,000    7/31/2017  Philadelphia
             nd       Spring                                 Children
             Enviro   Mill                                   Access
             nmenta   Road                                   Nature
             l        Gladwyn                                Program
             Educat   e, PA
             ion      19035
             Center
------------------------------------------------------------------------
Monetary    Sandy    2010              $2,000   11/21/2017  Sandy Sprint
             Rollma   West                                   Superhero
             n        Chester                                5K or 10K
             Ovaria   Pike,                                  Run/Walk
             n        Suite                                  and Canine
             Cancer   410                                    Sprint
             Founda   Haverto
             tion,    wn, PA
             Inc.     19083
------------------------------------------------------------------------
Monetary    Sarcoma  9899              $2,500   11/16/2017  Race to Cure
             Founda   Main                                   SarcomaT 5K
             tion     Street,                                Walk/Run
             of       #204                                   Series
             Americ   Damascu
             a        s, MD
                      20872
------------------------------------------------------------------------
Monetary    Special  2800              $4,000   11/21/2017  Special
             Equest   Street                                 Equestrians
             rians    Road                                   Equine-
                      P.O.                                   Assisted
                      Box                                    Learning
                      1001                                   and
                      Warring                                Therapeutic
                      ton, PA                                Riding
                      18976                                  Program
------------------------------------------------------------------------
Monetary    Starfin  4015             $10,000    5/24/2017  Starfinder's
             der      Main                                   Senior
             Founda   Street                                 Leaders
             tion     Philade                                Program
                      lphia,
                      PA
                      19127
------------------------------------------------------------------------
Monetary    The      222              $10,000   12/22/2017  Corporate
             Frankl   North                                  Membership
             in       20th
             Instit   Street
             ute      Philade
                      lphia,
                      PA
                      19103
------------------------------------------------------------------------
Monetary    The      PO Box            $2,000    7/31/2017  General
             Giving   823                                    Operating
             Tree,    Gwynedd                                Support
             Gwyned   Valley,
             d        PA
             Valley   19437
             , PA
------------------------------------------------------------------------
Monetary    The      3               $250,000    4/12/2017  FY 2018
             Leukem   Interna                                Light the
             ia and   tional                                 Night
             Lympho   Drive                                  National
             ma       Suite                                  Sponsor
             Societ   200 Rye
             y        Brook,
                      NY
                      10573
------------------------------------------------------------------------
Monetary    The      123               $7,500   12/14/2017  Master Class
             Mann     South                                  Artist
             Center   Broad                                  Residency
             for      Street
             the      Suite
             Perfor   815
             ming     Philade
             Arts     lphia,
                      PA
                      19109
------------------------------------------------------------------------
Monetary    The      2600             $10,000    4/25/2017  Hubert J.P.
             Melmar   Wayland                                Schoemaker
             k        Road                                   Classic
             Charit   Berwyn,
             able     PA
             Founda   19312
             tion
             Berwyn
             , PA
------------------------------------------------------------------------
Monetary    Travis   164 E             $5,000   12/13/2017  Character
             Manion   State                                  Does Matter
             Founda   Street
             tion     Doylest
                      own, PA
                      18901
------------------------------------------------------------------------
Monetary    Trustee  3025              $6,000   12/14/2017  WXPN
             s of     Walnut                                 Musicians
             the      Street                                 On Call
             Univer   Philade
             sity     lphia,
             of       PA
             Pennsy   19104
             lvania
------------------------------------------------------------------------
Monetary    Turning  415               $5,000    4/20/2017  Families and
             Points   South                                  Schools
             For      15th                                   Together
             Childr   Street                                 (FAST)
             en       Philade
                      lphia,
                      PA
                      19146
------------------------------------------------------------------------
Monetary    United   8085              $2,017     8/8/2017  General
             Mitoch   Saltsbu                                mission
             ondria   rg Road                                support
             l        Suite
             Diseas   201
             e        Pittsbu
             Founda   rgh, PA
             tion     15239
------------------------------------------------------------------------
Monetary    Us Too   2720              $1,000    5/25/2017  13th Annual
             Intern   South                                  SEA Blue
             ationa   River                                  Prostate
             l Inc.   Road                                   Cancer Walk
                      #112                                   & Run
                      Des
                      Plaines
                      , IL
                      60018
------------------------------------------------------------------------
Monetary    ZERO--T  515 King          $1,250     8/1/2017  ZERO
             he End   Street,                                Prostate
             of       Ste 420                                Cancer Run/
             Prosta   Alexand                                Walk
             te       ria, VA                                Austin, TX
             Cancer   22314
------------------------------------------------------------------------
Monetary    ZERO--T  515 King          $1,250     8/1/2017  ZERO
             he End   Street,                                Prostate
             of       Ste 420                                Cancer Run/
             Prosta   Alexand                                Walk
             te       ria, VA                                Columbus,
             Cancer   22314                                  OH
------------------------------------------------------------------------
Monetary    ZERO--T  515 King          $1,250     8/1/2017  ZERO
             he End   Street,                                Prostate
             of       Ste 420                                Cancer Run/
             Prosta   Alexand                                Walk
             te       ria, VA                                Charleston,
             Cancer   22314                                  SC
------------------------------------------------------------------------
Monetary    ZERO--T  515 King          $1,250     8/1/2017  ZERO
             he End   Street,                                Prostate
             of       Ste 420                                Cancer Run/
             Prosta   Alexand                                Walk
             te       ria, VA                                Boston, MA
             Cancer   22314
------------------------------------------------------------------------
Monetary    ZERO--T  515 King          $1,250     8/1/2017  ZERO
             he End   Street,                                Prostate
             of       Ste 420                                Cancer Run/
             Prosta   Alexand                                Walk
             te       ria, VA                                Cleveland,
             Cancer   22314                                  OH
------------------------------------------------------------------------
Monetary    ZERO--T  515 King          $1,250     8/1/2017  ZERO
             he End   Street,                                Prostate
             of       Ste 420                                Cancer Run/
             Prosta   Alexand                                Walk
             te       ria, VA                                Birmingham,
             Cancer   22314                                  AL
------------------------------------------------------------------------
Monetary    ZERO--T  515 King          $1,250     8/1/2017  ZERO
             he End   Street,                                Prostate
             of       Ste 420                                Cancer Run/
             Prosta   Alexand                                Walk San
             te       ria, VA                                Diego, CA
             Cancer   22314
------------------------------------------------------------------------
Monetary    ZERO--T  515 King          $1,250     8/1/2017  ZERO
             he End   Street,                                Prostate
             of       Ste 420                                Cancer Run/
             Prosta   Alexand                                Walk San
             te       ria, VA                                Antonio, TX
             Cancer   22314
------------------------------------------------------------------------
Monetary    ZERO--T  515 King          $1,250     8/1/2017  ZERO
             he End   Street,                                Prostate
             of       Ste 420                                Cancer Run/
             Prosta   Alexand                                Walk
             te       ria, VA                                Sacramento,
             Cancer   22314                                  CA
------------------------------------------------------------------------
Monetary    ZERO--T  515 King          $1,250     8/1/2017  ZERO
             he End   Street,                                Prostate
             of       Ste 420                                Cancer Run/
             Prosta   Alexand                                Walk
             te       ria, VA                                Oklahoma
             Cancer   22314                                  City, OK
------------------------------------------------------------------------
Monetary    ZERO--T  515 King          $1,250     8/1/2017  ZERO
             he End   Street,                                Prostate
             of       Ste 420                                Cancer Run/
             Prosta   Alexand                                Walk East
             te       ria, VA                                Lansing, MI
             Cancer   22314
------------------------------------------------------------------------
Monetary    ZERO--T  515 King          $1,250     8/1/2017  ZERO
             he End   Street,                                Prostate
             of       Ste 420                                Cancer Run/
             Prosta   Alexand                                Walk Kansas
             te       ria, VA                                City, KS
             Cancer   22314
------------------------------------------------------------------------
Monetary    ZERO--T  515 King          $1,250     8/1/2017  ZERO
             he End   Street,                                Prostate
             of       Ste 420                                Cancer Run/
             Prosta   Alexand                                Walk
             te       ria, VA                                Jacksonvill
             Cancer   22314                                  e, FL
------------------------------------------------------------------------
Monetary    ZERO--T  515 King          $1,250     8/1/2017  ZERO
             he End   Street,                                Prostate
             of       Ste 420                                Cancer Run/
             Prosta   Alexand                                Walk
             te       ria, VA                                Harrisburg,
             Cancer   22314                                  PA
------------------------------------------------------------------------
Monetary    ZERO--T  515 King          $1,250     8/1/2017  ZERO
             he End   Street,                                Prostate
             of       Ste 420                                Cancer Run/
             Prosta   Alexand                                Walk
             te       ria, VA                                Greensboro,
             Cancer   22314                                  NC
------------------------------------------------------------------------
Monetary    ZERO--T  515 King          $1,250     8/1/2017  ZERO
             he End   Street,                                Prostate
             of       Ste 420                                Cancer Run/
             Prosta   Alexand                                Walk Des
             te       ria, VA                                Moines, IA
             Cancer   22314
------------------------------------------------------------------------
Monetary    ZERO--T  515 King          $1,250     8/1/2017  ZERO
             he End   Street,                                Prostate
             of       Ste 420                                Cancer Run/
             Prosta   Alexand                                Walk
             te       ria, VA                                Dayton, OH
             Cancer   22314
------------------------------------------------------------------------
Monetary    ZERO--T  515 King          $1,250     8/1/2017  ZERO
             he End   Street,                                Prostate
             of       Ste 420                                Cancer Run/
             Prosta   Alexand                                Walk Dallas/
             te       ria, VA                                Fort Worth,
             Cancer   22314                                  TX
------------------------------------------------------------------------
Monetary    ZERO--T  515 King          $1,250     8/1/2017  ZERO
             he End   Street,                                Prostate
             of       Ste 420                                Cancer Run/
             Prosta   Alexand                                Walk Corpus
             te       ria, VA                                Christi, TX
             Cancer   22314
------------------------------------------------------------------------
Monetary    ZERO--T  515 King          $1,250     8/1/2017  ZERO
             he End   Street,                                Prostate
             of       Ste 420                                Cancer Run/
             Prosta   Alexand                                Walk
             te       ria, VA                                Virginia
             Cancer   22314                                  Beach, VA
------------------------------------------------------------------------
Monetary    ZERO--T  515 King          $1,250     8/1/2017  ZERO
             he End   Street,                                Prostate
             of       Ste 420                                Cancer Run/
             Prosta   Alexand                                Walk Tyler,
             te       ria, VA                                TX
             Cancer   22314
------------------------------------------------------------------------
Monetary    ZERO--T  515 King          $1,250     8/1/2017  ZERO
             he End   Street,                                Prostate
             of       Ste 420                                Cancer Run/
             Prosta   Alexand                                Walk St.
             te       ria, VA                                Louis, MO
             Cancer   22314
------------------------------------------------------------------------
Monetary    ZERO--T  515 King          $1,250     8/1/2017  ZERO
             he End   Street,                                Prostate
             of       Ste 420                                Cancer Run/
             Prosta   Alexand                                Walk Puget
             te       ria, VA                                Sound, WA
             Cancer   22314
------------------------------------------------------------------------
Monetary    ZERO--T  515 King          $1,250     8/1/2017  ZERO
             he End   Street,                                Prostate
             of       Ste 420                                Cancer Run/
             Prosta   Alexand                                Walk San
             te       ria, VA                                Francisco,
             Cancer   22314                                  CA
------------------------------------------------------------------------
Monetary    ZERO--T  515 King          $1,000     8/1/2017  ZERO
             he End   Street,                                Prostate
             of       Ste 420                                Cancer Run/
             Prosta   Alexand                                Walk Napa
             te       ria, VA                                Valley, CA
             Cancer   22314
------------------------------------------------------------------------
Monetary    ZERO--T  515 King          $1,250     8/1/2017  ZERO
             he End   Street,                                Prostate
             of       Ste 420                                Cancer Run/
             Prosta   Alexand                                Walk
             te       ria, VA                                Minneapolis
             Cancer   22314                                  , MN
------------------------------------------------------------------------
Monetary    ZERO--T  515 King          $1,250     8/1/2017  ZERO
             he End   Street,                                Prostate
             of       Ste 420                                Cancer Run/
             Prosta   Alexand                                Walk
             te       ria, VA                                Hollywood,
             Cancer   22314                                  FL
------------------------------------------------------------------------
Monetary    ZERO--T  515 King          $1,250     8/1/2017  ZERO
             he End   Street,                                Prostate
             of       Ste 420                                Cancer Run/
             Prosta   Alexand                                Walk
             te       ria, VA                                Asheville,
             Cancer   22314                                  NC
------------------------------------------------------------------------
Monetary    ZERO--T  515 King          $1,250     8/1/2017  ZERO
             he End   Street,                                Prostate
             of       Ste 420                                Cancer Run/
             Prosta   Alexand                                Walk
             te       ria, VA                                Augusta, SC
             Cancer   22314
------------------------------------------------------------------------
Monetary    ZERO--T  515 King          $1,250     8/1/2017  ZERO
             he End   Street,                                Prostate
             of       Ste 420                                Cancer Run/
             Prosta   Alexand                                Walk Towson/
             te       ria, VA                                Baltimore,
             Cancer   22314                                  MD
------------------------------------------------------------------------
Monetary    ZERO--T  515 King          $1,250     8/1/2017  ZERO
             he End   Street,                                Prostate
             of       Ste 420                                Cancer Run/
             Prosta   Alexand                                Walk El
             te       ria, VA                                Paso, TX
             Cancer   22314
------------------------------------------------------------------------
Monetary    ZERO--T  515 King          $1,250     8/1/2017  ZERO
             he End   Street,                                Prostate
             of       Ste 420                                Cancer Run/
             Prosta   Alexand                                Walk
             te       ria, VA                                Hartford,
             Cancer   22314                                  CT
------------------------------------------------------------------------
Monetary    ZERO--T  515 King          $1,250     8/1/2017  ZERO
             he End   Street,                                Prostate
             of       Ste 420                                Cancer Run/
             Prosta   Alexand                                Walk
             te       ria, VA                                Wichita, KS
             Cancer   22314
------------------------------------------------------------------------
Monetary    ZERO--T  515 King          $1,250     8/1/2017  ZERO
             he End   Street,                                Prostate
             of       Ste 420                                Cancer Run/
             Prosta   Alexand                                Walk
             te       ria, VA                                Capital
             Cancer   22314                                  Area/
                                                             Arlington,
                                                             VA
------------------------------------------------------------------------
Monetary    ZERO--T  515 King          $1,250     8/1/2017  ZERO
             he End   Street,                                Prostate
             of       Ste 420                                Cancer Run/
             Prosta   Alexand                                Walk
             te       ria, VA                                Syracuse,
             Cancer   22314                                  NY
------------------------------------------------------------------------
Monetary    ZERO--T  515 King          $1,250     8/1/2017  ZERO
             he End   Street,                                Prostate
             of       Ste 420                                Cancer Run/
             Prosta   Alexand                                Walk Salt
             te       ria, VA                                Lake City,
             Cancer   22314                                  UT
------------------------------------------------------------------------
Monetary    ZERO--T  515 King          $1,250     8/1/2017  ZERO
             he End   Street,                                Prostate
             of       Ste 420                                Cancer Run/
             Prosta   Alexand                                Walk
             te       ria, VA                                Raleigh, NC
             Cancer   22314
------------------------------------------------------------------------
Monetary    ZERO--T  515 King          $1,250     8/1/2017  ZERO
             he End   Street,                                Prostate
             of       Ste 420                                Cancer Run/
             Prosta   Alexand                                Walk
             te       ria, VA                                Portland,
             Cancer   22314                                  OR
------------------------------------------------------------------------
Monetary    ZERO--T  515 King          $1,250     8/1/2017  ZERO
             he End   Street,                                Prostate
             of       Ste 420                                Cancer Run/
             Prosta   Alexand                                Walk Los
             te       ria, VA                                Angeles, CA
             Cancer   22314
------------------------------------------------------------------------
Monetary    ZERO--T  515 King          $1,250     8/1/2017  ZERO
             he End   Street,                                Prostate
             of       Ste 420                                Cancer Run/
             Prosta   Alexand                                Walk
             te       ria, VA                                Lincoln, NE
             Cancer   22314
------------------------------------------------------------------------
Monetary    ZERO--T  515 King          $1,250     8/1/2017  ZERO
             he End   Street,                                Prostate
             of       Ste 420                                Cancer Run/
             Prosta   Alexand                                Walk Lehigh
             te       ria, VA                                Valley, PA
             Cancer   22314
------------------------------------------------------------------------
Monetary    ZERO--T  515 King         $20,000    6/16/2017  Printed News
             he End   Street,                                Resource
             of       Ste 420                                for Men
             Prosta   Alexand                                Living with
             te       ria, VA                                Advanced
             Cancer   22314                                  Disease
------------------------------------------------------------------------
Product     Johnson  One         $497,856,557   12/31/2017  Patient
             &        Johnson                                Assistance
             Johnso   &                                      Product
             n        Johnson                                Donation
             Patien   Plaza
             t        Kilmer
             Assist   Square,
             ance     Suite
             Founda   130 New
             tion     Brunswi
                      ck, NJ
                      08933
------------------------------------------------------------------------
Janssen has also made financial donations to independent charitable
  foundations that assist patients who are underinsured and in financial
  need with treatment-related expenses. In keeping with our donor
  agreements and applicable regulatory guidance, we will only disclose
  aggregate data on our charitable giving and do not publicize
  information on donations to specific foundations and disease states.
  In 2017, we contributed approximately $61 million in donations to
  independent charitable foundations, enabling them to provide
  assistance with medication-related copays to patients with cancer and
  autoimmune diseases.Updated
 
Updated March 30, 2018


Janssen Pharmaceuticals, Inc. Monetary and Product Contribution to U.S.-
              based Charitable Organizations Full Year 2017
        (Payments made from January 1, 2017 to December 31, 2017)
------------------------------------------------------------------------
                                                               Project
 Donation    Payee     Payee   Payment Amount    Payment       Title/
   Type               Address       (USD)          Date      Description
------------------------------------------------------------------------
Monetary    180      1                 $2,500    12/5/2017  2NDFLOOR
             Turnin   Bethany                                Youth
             g        Road,                                  Helpline--H
             Lives    Buildin                                unterdon,
             Around   g 3                                    Mercer,
             , Inc.   Suite                                  Somerset
                      42                                     Operations
                      Hazlet,
                      NJ
                      07730
------------------------------------------------------------------------
Monetary    Adult    872 E.              $300    11/6/2017  Costs
             Day      Main                                   associated
             Center   Street                                 with
             of       Bridgew                                Janssen
             Somers   ater,                                  Cares
             et       NJ                                     Volunteer
             County   08807                                  Activity--O
                                                             ctober 4,
                                                             2017
------------------------------------------------------------------------
Monetary    Allianc  2021 K           $20,000   12/28/2017  ``Living
             e For    Street                                 with Atrial
             Aging    N.W.                                   Fibrillatio
             Resear   Suite                                  n'' Stroke
             ch       305                                    Prevention
                      Washing                                PSA
                      ton, DC                                Campaign
                      20006
------------------------------------------------------------------------
Monetary    Allies,  1262              $7,500    11/6/2017  Project Grow
             Inc.     Whiteho
                      rse
                      Hamilto
                      n
                      Square
                      Rd.
                      Hamilto
                      n, NJ
                      08690
------------------------------------------------------------------------
Monetary    Alterna  600                 $300    9/29/2017  Costs
             tives    First                                  associated
                      Ave.                                   with
                      Raritan                                Janssen
                      , NJ                                   Cares
                      08869                                  Volunteer
                                                             Activity
                                                             #2--Septemb
                                                             er 12, 2017
------------------------------------------------------------------------
Monetary    Alterna  600                 $300    9/29/2017  Costs
             tives    First                                  associated
                      Ave.                                   with
                      Raritan                                Janssen
                      , NJ                                   Cares
                      08869                                  Volunteer
                                                             Activity
                                                             #1--Septemb
                                                             er 12, 2017
------------------------------------------------------------------------
Monetary    Alterna  600               $7,500   12/13/2017  Fundraising
             tives    First                                  event
                      Ave.                                   support to
                      Raritan                                benefit
                      , NJ                                   general
                      08869                                  mission of
                                                             organizatio
                                                             n
------------------------------------------------------------------------
Monetary    America  900 Fort         $10,000     5/2/2017  Stop
             n        Street                                 Diabetes @
             Diabet   Mall,                                  Work
             es       Suite
             Associ   940
             ation    Honolul
                      u, HI
                      96813
------------------------------------------------------------------------
Monetary    America  PO Box           $30,000   12/22/2017  Atrial
             n        541                                    Fibrillatio
             Founda   Greenwo                                n Patient
             tion     od, TX                                 Education
             For      76246                                  Conference,
             Women'                                          AF Patient
             s                                               Treatment
             Health                                          and Stroke
                                                             Prevention
                                                             Decision-
                                                             Making
                                                             Tool, and
                                                             AF
                                                             Community
                                                             Screening
                                                             Pilot
------------------------------------------------------------------------
Monetary    America  7272             $30,000   12/28/2017  Raising
             n        Greenvi                                Awareness
             Heart    lle Ave                                on the
                      Dallas,                                Effects and
                      TX                                     Consequence
                      75231                                  s of
                                                             Untreated
                                                             Type 2
                                                             Diabetes
------------------------------------------------------------------------
Monetary    America  7272             $30,000   12/28/2017  Increasing
             n        Greenvi                                Awareness
             Heart    lle Ave                                of Deep
                      Dallas,                                Vein
                      TX                                     Thrombosis/
                      75231                                  Venous
                                                             Thromboembo
                                                             lism in
                                                             General
                                                             Population
                                                             and At-Risk
                                                             Patients
------------------------------------------------------------------------
Monetary    America  One                 $300    9/29/2017  Costs
             n        Union                                  associated
             Heart    Street                                 with
             Associ   Suite                                  Janssen
             ation-   301                                    Cares
             -New     Robbins                                Volunteer
             Jersey   ville,                                 Activity--O
                      NJ                                     ctober 7,
                      08691                                  2017
------------------------------------------------------------------------
Monetary    America  One               $5,000    12/4/2017  16th Annual
             n        Union                                  Garden
             Heart    Street                                 State Go
             Associ   Suite                                  Red For
             ation-   301                                    Women
             -New     Robbins                                Luncheon
             Jersey   ville,
                      NJ
                      08691
------------------------------------------------------------------------
Monetary    America  1000            $200,000   12/12/2017  Judges and
             n        Wilson                                 Psychiatris
             Psychi   Blvd,                                  ts
             atric    Suite                                  Leadership
             Founda   1825                                   Initiative
             tion     Arlingt                                (JPLI)
                      on, VA
                      22209
------------------------------------------------------------------------
Monetary    America  1000            $100,000   12/12/2017  Typical or
             n        Wilson                                 Troubled?
             Psychi   Blvd,                                  School
             atric    Suite                                  Mental
             Founda   1825                                   Health
             tion     Arlingt                                Education
                      on, VA                                 Program
                      22209
------------------------------------------------------------------------
Monetary    America  1000             $35,000   12/12/2017  Center for
             n        Wilson                                 Workplace
             Psychi   Blvd,                                  Mental
             atric    Suite                                  Health
             Founda   1825                                   (formerly
             tion     Arlingt                                the
                      on, VA                                 Partnership
                      22209                                  for
                                                             Workplace
                                                             Mental
                                                             Health)
------------------------------------------------------------------------
Monetary    America  88                  $600   11/28/2017  Donation In
             res      Hamilto                                Lieu of
             Founda   n Ave.                                 Gift
             tion     Stamfor
                      d, CT
                      06902
------------------------------------------------------------------------
Monetary    America  150                 $300    9/29/2017  Costs
             's       Pittsto                                associated
             Grow-A-  wn Road                                with
             Row,     Pittsto                                Janssen
             Inc.     wn, NJ                                 Cares
                      08867                                  Volunteer
                                                             Activity--S
                                                             eptember
                                                             27, 2017
------------------------------------------------------------------------
Monetary    America  150                 $300    9/29/2017  Costs
             's       Pittsto                                associated
             Grow-A-  wn Road                                with
             Row,     Pittsto                                Janssen
             Inc.     wn, NJ                                 Cares
                      08867                                  Volunteer
                                                             Activity--O
                                                             ctober 6,
                                                             2017
------------------------------------------------------------------------
Monetary    Anchor   482                 $300    9/29/2017  Costs
             House,   Centre                                 associated
             Inc.     Street                                 with
                      Trenton                                Janssen
                      , NJ                                   Cares
                      08611                                  Volunteer
                                                             Activity--S
                                                             eptember
                                                             28, 2017
------------------------------------------------------------------------
Monetary    Anchor   482               $8,000   12/12/2017  Anchor House
             House,   Centre                                 Shelter
             Inc.     Street
                      Trenton
                      , NJ
                      08611
------------------------------------------------------------------------
Monetary    Ann      595 W.            $9,500   12/12/2017  Increasing
             Silver   State                                  Access to
             man      Street                                 Comprehensi
             Commun   Doylest                                ve
             ity      own, PA                                Healthcare
             Health   18901                                  for Low-
             Clinic                                          Income,
                                                             Uninsured
                                                             Bucks
                                                             County
                                                             residents
------------------------------------------------------------------------
Monetary    Arm In   123 E.           $15,000   10/30/2017  Improving
             Arm,     Hanover                                Food
             Inc.     St.                                    Security
                      Trenton                                and Housing
                      , NJ                                   Stability
                      08608
------------------------------------------------------------------------
Monetary    Bear     1162                $750   12/12/2017  2018 Bear
             Tavern   Bear                                   Tavern
             Parent   Tavern                                 Elementary
             s        Road                                   Science
             Associ   Titusvi                                Fair
             ation    lle, NJ
                      08560
------------------------------------------------------------------------
Monetary    Big      2875              $6,500   10/30/2017  STEM School
             Brothe   York                                   Mentoring
             rs Big   Road                                   Initiative
             Sister   Jamison
             s of     , PA
             Bucks    18929
             County
------------------------------------------------------------------------
Monetary    Big      535 East         $10,000    8/23/2017  Fundraising
             Brothe   Frankli                                event
             rs Big   n                                      support to
             Sister   Street                                 benefit
             s of     Trenton                                general
             Mercer   , NJ                                   mission of
             County   08610                                  organizatio
                                                             n
------------------------------------------------------------------------
Monetary    Big      535 East          $7,500   10/16/2017  Youth
             Brothe   Frankli                                Mentoring
             rs Big   n                                      Programs
             Sister   Street
             s of     Trenton
             Mercer   , NJ
             County   08610
------------------------------------------------------------------------
Monetary    Boys     212              $20,000   10/30/2017  Extended Day
             and      Centre                                 Learning
             Girls    Trenton
             Club     , NJ
             of       08611
             Trento
             n and
             Mercer
             County
------------------------------------------------------------------------
Monetary    Bristol  120               $7,500    11/6/2017  ArtRageous
             Rivers   Radclif                                Theatre
             ide      fe                                     Arts
             Theate   Street                                 Education
             r Co     P.O.                                   Program
             Inc.     Box
                      1250
                      Bristol
                      , PA
                      19007
------------------------------------------------------------------------
Monetary    Britesi  16 Sand             $300   11/15/2017  Costs
             de       Hill                                   associated
             Adult    Road                                   with
             Day      Fleming                                Janssen
             Center   ton, NJ                                Cares
             s,       08822                                  Volunteer
             Inc.                                            Activity--S
                                                             eptember
                                                             22, 2017
------------------------------------------------------------------------
Monetary    Broward  305 SE           $15,000    6/28/2017  Affordable
             County   18th                                   Housing
             Commun   Court
             ity      Fort
             Develo   Lauderd
             pment    ale, FL
             Corpor   33316
             ation,
             Inc.
------------------------------------------------------------------------
Monetary    Bucks    400                 $300    9/20/2017  Costs
             County   Freedom                                associated
             Associ   Drive                                  with
             ation    Newtown                                Janssen
             For      , PA                                   Cares
             The      18940                                  Volunteer
             Blind                                           Activity--S
             And                                             eptember
             Visual                                          26, 2017
             ly
             Impair
             ed
------------------------------------------------------------------------
Monetary    Bucks    626               $5,000   12/18/2017  Veterans
             County   Jackson                                Housing
             Housin   ville                                  Assistance
             g        Road                                   Program
             Group    Suite
                      140
                      Warmins
                      ter, PA
                      18974
------------------------------------------------------------------------
Monetary    Bucks    100              $10,000   12/21/2017  Economic
             County   Doyle                                  Self-
             Opport   Street                                 Sufficiency
             unity    Doylest                                Program
             Counci   own, PA
             l,       18901
             Inc.
------------------------------------------------------------------------
Monetary    Caminar  2600 S.           $7,500    8/11/2017  Bridges to
                      El                                     Wellness
                      Camino                                 Program
                      Real,
                      Suite
                      200 San
                      Mateo,
                      CA
                      94403
------------------------------------------------------------------------
Monetary    Capital  PO Box            $8,000     2/1/2017  ``I Am
             City     1743                                   Trenton!'':
             Commun   Trenton                                Positive
             ity      , NJ                                   Images
             Founda   08607-1                                Campaign
             tion     743
------------------------------------------------------------------------
Monetary    Catholi  920               $5,000    12/5/2017  CYO's Broad
             c        South                                  St. Trenton
             Youth    Broad                                  Center's
             Organi   St.                                    After
             zation   Trenton                                School
             of       , NJ                                   Program
             Mercer   08611                                  Tutoring
             County                                          Project
------------------------------------------------------------------------
Monetary    Center   151              $10,000   10/13/2017  Community-
             for      Lawrenc                                Based
             Altern   e                                      Health
             ative    Street                                 Services
             Senten   3rd                                    for Justice-
             cing     Floor                                   Involved
             and      Brookly                                Adults with
             Employ   n, NY                                  Schizophren
             ment     11201                                  ia
             Servic
             es
             (CASES
             )
------------------------------------------------------------------------
Monetary    Central  2500              $5,000    10/3/2017  Diabetes
             Bucks    Lower                                  Prevention
             Family   State                                  Program
             YMCA     Road
                      Doylest
                      own, PA
                      18901
------------------------------------------------------------------------
Monetary    Child    204 N.            $3,000     3/8/2017  Upper Bucks
             Home     West                                   Area Young
             and      Street                                 Parent
             Commun   #101                                   Initiative
             ity      Doylest
                      own, PA
                      18901
------------------------------------------------------------------------
Monetary    Childre  635              $10,000   11/20/2017  CUNA and
             n's      South                                  Body and
             Home     Clinton                                Soul
             Societ   Avenue                                 Prenatal
             y of     Trenton                                Health
             New      , NJ                                   Education
             Jersey   08611                                  for Low-
                                                             Income
                                                             Women
------------------------------------------------------------------------
Monetary    CIT      111 S.            $5,000    8/15/2017  CIT
             Intern   Highlan                                Internation
             ationa   d St.                                  al
             l,       Box 71                                 Conference
             Inc.     Memphis                                2017
                      , TN
                      38111
------------------------------------------------------------------------
Monetary    Clevela  9500             $20,000   10/25/2017  Diabetes
             nd       Euclid                                 Center
             Clinic   Ave.,                                  Educational
             Founda   DV4                                    Initiatives
             tion     Clevela                                at
                      nd, OH                                 Cleveland
                      44195                                  Clinic
                                                             South
                                                             Pointe
                                                             Hospital
------------------------------------------------------------------------
Monetary    College  50 Milk          $20,000   12/28/2017  Campus
             Diabet   St 16th                                Quality
             es       Floor                                  Improvement
             Networ   Boston,                                : Diabetes
             k        MA                                     and Higher
             (CDN)    02109                                  Education
------------------------------------------------------------------------
Monetary    College  2000             $20,000   11/20/2017  Nursing
             of New   Penning                                Merit
             Jersey   ton                                    Scholarship
                      Road                                   s $7,500;
                      P.O.                                   and
                      Box                                    Educational
                      7718                                   Opportunity
                      Ewing,                                 Fund (EOF)
                      NJ                                     Promise
                      08628                                  Awards
                                                             $12,500
------------------------------------------------------------------------
Monetary    Communi  P.O. Box          $5,000    12/5/2017  Rise Summer
             ty       88 116                                 Healthy
             Action   North                                  Food
             Servic   Main                                   Initiative
             e        Street                                 for Low-
             Center   Hightst                                Income
             , Inc.   own, NJ                                Youth
                      08520-
                      9804
------------------------------------------------------------------------
Monetary    Communi  4059              $5,000     3/8/2017  Arts for
             ty       Skyron                                 Seniors
             Conser   Drive                                  ($3,000)
             vatory   Doylest                                and Music
             of       own, PA                                Therapy
             Music    18902                                  ($2,000)
------------------------------------------------------------------------
Monetary    Communi  4059              $4,500    11/6/2017  Making the
             ty       Skyron                                 Arts
             Conser   Drive                                  Accessible
             vatory   Doylest                                for Seniors
             of       own, PA                                and Persons
             Music    18902                                  with
                                                             Disabilitie
                                                             s: Music
                                                             Therapy and
                                                             Arts for
                                                             Seniors
------------------------------------------------------------------------
Monetary    Communi  P.O. Box         $60,000   12/18/2017  HealtheVoice
             ty       338                                    sTM Impact
             Founda   Morrist                                Fund
             tion     own, NJ
             of New   07963-
             Jersey   0338
------------------------------------------------------------------------
Monetary    Communi  P.O. Box         $75,000   12/18/2017  Healthcare
             ty       338                                    and Basic
             Founda   Morrist                                Needs Fund
             tion     own, NJ
             of New   07963-
             Jersey   0338
------------------------------------------------------------------------
Monetary    Communi  P.O. Box         $14,000    7/17/2017  ``Each One,
             ty       15176                                  Teach
             Health   407                                    One'':
             Coalit   Crutchf                                Community
             ion,     ield                                   Empowerment
             Inc.     Street                                 Diabetes
                      Durham,                                Self-
                      NC                                     Management
                      27704                                  Education
                                                             Program
------------------------------------------------------------------------
Monetary    Communi  959              $11,000    6/14/2017  Pathway to
             ty       Route                                  Recovery
             Hope,    46 East                                Residential
             Inc.     Suite                                  Programs/
                      402                                    The Annual
                      Parsipp                                Forum and
                      any, NJ                                Wellness
                      07054                                  Fair
------------------------------------------------------------------------
Monetary    Communi  959              $15,000   10/16/2017  Hope for
             ty       Route                                  Veterans
             Hope,    46 East                                and Valley
             Inc.     Suite                                  Brook
                      402                                    Village for
                      Parsipp                                Veterans
                      any, NJ
                      07054
------------------------------------------------------------------------
Monetary    Communi  310 W.            $5,000   12/18/2017  Basic Needs:
             ty       State                                  Legal
             Justic   Street,                                Services
             e        3rd
             Center   Floor
             , Inc.   Trenton
                      , NJ
                      08618
------------------------------------------------------------------------
Monetary    Compeer  259               $2,500    5/31/2017  Caregiver
             Roches   Monroe                                 Support
             ter,     Avenue
             Inc.     Rochest
                      er, NY
                      14607
------------------------------------------------------------------------
Monetary    Contact  60 S.             $8,500    12/4/2017  Emotional
             Of       Main                                   Support and
             Mercer   St.                                    Crisis
             County   Penning                                Services:
             New      ton, NJ                                HOTLINE,
             Jersey   08628                                  Crisis Chat
             Inc.                                            and
                                                             TxtToday
------------------------------------------------------------------------
Monetary    CONTACT  P.O. Box          $4,000    10/4/2017  Training
             We       2376                                   Nonprofessi
             Care,    Westfie                                onals in
             Inc.     ld, NJ                                 Crisis
                      07091                                  Interventio
                                                             n for
                                                             People
                                                             Experiencin
                                                             g Psychosis
------------------------------------------------------------------------
Monetary    Court    1450                $300    8/29/2017  Costs
             Appoin   Parksid                                associated
             ted      e                                      with
             Specia   Avenue,                                Janssen
             l        Suite                                  Cares
             Advoca   22                                     Volunteer
             tes      Ewing,                                 Activity--S
                      NJ                                     eptember
                      08638-                                 12, 2017
                      2946
------------------------------------------------------------------------
Monetary    Court    1450             $15,000   11/20/2017  General
             Appoin   Parksid                                mission
             ted      e                                      support
             Specia   Avenue,
             l        Suite
             Advoca   22
             tes      Ewing,
                      NJ
                      08638-
                      2946
------------------------------------------------------------------------
Monetary    Deborah  212               $5,000   12/22/2017  2018 Women's
             Hospit   Trenton                                Heart
             al       Road                                   Health
             Founda   Browns                                 Educational
             tion     Mills,                                 Expo
                      NJ
                      08015
------------------------------------------------------------------------
Monetary    Delawar  14                $4,500    11/6/2017  Environmenta
             e        Michael                                l education
             River    McCorri                                for
             Steamb   stin                                   underfunded
             oat      Road                                   and
             Floati   Hamilto                                underserved
             ng       n, NJ                                  schools and
             Classr   08690                                  youth
             oom,                                            groups
             Inc.
------------------------------------------------------------------------
Monetary    Depress  5                 $1,000     3/8/2017  DBSA NJ
             ion      Village                                Mutual Aid
             and      Ct.                                    Support
             Bipola   Lawrenc                                Group
             r        eville,                                Facilitator
             Suppor   NJ                                     Training
             t        08648
             Allian
             ce
------------------------------------------------------------------------
Monetary    Diabete  14652             $5,000    3/23/2017  The Diabetes
             s        Corkwoo                                UnConferenc
             Collec   d Drive                                e
             tive,    Tampa,
             Inc.     FL
                      33626
------------------------------------------------------------------------
Monetary    Dress    3131             $10,000   10/16/2017  Women's
             for      Princet                                Empowerment
             Succes   on Pike                                Programs
             s        Buildin
                      g 4,
                      Suite
                      209
                      Lawrenc
                      eville,
                      NJ
                      08648
------------------------------------------------------------------------
Monetary    Eden     2                $10,000   10/16/2017  Adult
             Autism   Merwick                                Employment
             Servic   Road                                   Program
             es       Princet
             Founda   on, NJ
             tion     08540
------------------------------------------------------------------------
Monetary    Eden     2                $10,000   12/18/2017  Eden Dreams
             Autism   Merwick                                Sponsorship
             Servic   Road
             es       Princet
             Founda   on, NJ
             tion     08540
------------------------------------------------------------------------
Monetary    Emory    550               $3,500     7/3/2017  Atrial
             Univer   Peachtr                                Fibrillatio
             sity     ee                                     n Support
                      Street                                 Group
                      6th Fl,                                Meeting
                      Suite
                      4300
                      Atlanta
                      , GA
                      30308
------------------------------------------------------------------------
Monetary    Enable,  13                $7,500   12/12/2017  Connect with
             Inc.     Roszel                                 Enable--Div
                      Road,                                  ersity
                      Suite                                  Drive
                      B110
                      Princet
                      on, NJ
                      08540
------------------------------------------------------------------------
Monetary    Every    Fred              $9,000    12/4/2017  Every Child
             Child    Vereen,                                Valued
             Valued   Jr.                                    (ECV) After
             A NJ     Communi                                School
             Nonpro   ty                                     Program
             fit      Center
             Corpor   175
             ation    Johnson
                      Avenue
                      Lawrenc
                      eville,
                      NJ
                      08648
------------------------------------------------------------------------
Monetary    Everybo  707               $7,500    12/4/2017  Coming Up
             dy       Alexand                                for AIRTM
             Loves    er
             Kenny    Road,
             Projec   Suite
             t Inc.   208
                      Princet
                      on, NJ
                      08540
------------------------------------------------------------------------
Monetary    Familie  320 N.            $3,500    8/29/2017  DBT-Based
             s and    Goodman                                Coping
             Friend   St.,                                   Skills for
             s of     Suite                                  Families
             the      102
             Mental   Rochest
             ly Ill   er, NY
             and      14607
             Emotio
             nally
             Distur
             bed,
             Inc,
             dba
             NAMI-
             Roches
             ter
------------------------------------------------------------------------
Monetary    Family   1931                $300    8/24/2017  Costs
             Guidan   Notting                                associated
             ce       ham Way                                with
             Center   Hamilto                                Janssen
             Corpor   n, NJ                                  Cares
             ation    08619                                  Volunteer
                                                             Activity--S
                                                             eptember
                                                             28, 2017
------------------------------------------------------------------------
Monetary    Family   1931             $10,000   10/27/2017  Outpatient
             Guidan   Notting                                mental
             ce       ham Way                                health
             Center   Hamilto                                treatment
             Corpor   n, NJ                                  for
             ation    08619                                  homeless
                                                             women and
                                                             children.
------------------------------------------------------------------------
Monetary    Family   1 AAA Dr         $12,500   11/20/2017  Caregiver
             Resour   Suite                                  Wellness
             ce       203                                    Series
             Networ   Trenton
             k        , NJ
                      08691
------------------------------------------------------------------------
Monetary    Family   4                $14,000    12/4/2017  Nurse
             Servic   Corners                                Educator at
             e        tone                                   Bucks
             Associ   Drive                                  County
             ation    Langhor                                Emergency
             of       ne, PA                                 Homeless
             Bucks    19047                                  Shelter
             County
------------------------------------------------------------------------
Monetary    Federat  One               $2,500    5/31/2017  Big Nosh
             ion of   Farming                                Vocational
             Organi   dale                                   Services
             zation   Road                                   Program
             s        West
                      Babylon
                      , NY
                      11704
------------------------------------------------------------------------
Monetary    Feed     Central              $75    2/24/2017  Employee
             More,    Virgini                                directed
             Inc.     a Food                                 donation in
                      Bank                                   lieu of
                      1415                                   company
                      Rhoadmi                                holiday
                      ller                                   gift
                      Street
                      Richmon
                      d, VA
                      23220
------------------------------------------------------------------------
Monetary    Florida  2525              $1,500   10/13/2017  2017 Florida
             Coalit   Saint                                  Institute
             ion      Lucie                                  on
             for      Avenue                                 Homelessnes
             the      Vero                                   s and
             Homele   Beach,                                 Supportive
             ss,      FL                                     Housing
             Inc.     32960
------------------------------------------------------------------------
Monetary    Forsyth  4881                 $75    4/11/2017  Employee
             Humane   Country                                directed
             Societ   Club                                   donation in
             y        Rd.                                    lieu of
                      Winston                                company
                      Salem,                                 holiday
                      NC                                     gift
                      27104
------------------------------------------------------------------------
Monetary    Foundat  2381              $2,500    12/5/2017  Funding
             ion of   Lawrenc                                support for
             Morris   eville                                 the 2018
             Hall/    Road                                   Philly Pops
             St.      Lawrenc                                Benefit
             Lawren   eville,                                Concert
             ce       NJ
                      08648
------------------------------------------------------------------------
Monetary    Foundat  2381              $7,000    12/5/2017  It's Never 2
             ion of   Lawrenc                                Late
             Morris   eville
             Hall/    Road
             St.      Lawrenc
             Lawren   eville,
             ce       NJ
                      08648
------------------------------------------------------------------------
Monetary    Fountai  425 West          $2,500   10/16/2017  Danny Zorn
             n        47th                                   Scholarship
             House    Street                                 Fund
                      New
                      York,
                      NY
                      10036
------------------------------------------------------------------------
Monetary    Fountai  425 West          $6,000   10/16/2017  Mad About
             n        47th                                   Art Auction
             House    Street                                 and Benefit
                      New
                      York,
                      NY
                      10036
------------------------------------------------------------------------
Monetary    Fountai  425 West          $1,000    3/23/2017  Fountain
             n        47th                                   House One-
             House    Street                                 in-Four 5K
                      New
                      York,
                      NY
                      10036
------------------------------------------------------------------------
Monetary    Friends  P.O. Box         $10,125   11/20/2017  Project
             Of       395                                    Hopewell
             Hopewe   Penning                                Healthy
             ll       ton, NJ                                Habitats
             Valley   08534
             Open
             Space
------------------------------------------------------------------------
Monetary    Friends  P.O. Box          $2,500   10/27/2017  Fundraising
             Of       395                                    event
             Hopewe   Penning                                support to
             ll       ton, NJ                                benefit
             Valley   08534                                  general
             Open                                            mission of
             Space                                           organizatio
                                                             n
------------------------------------------------------------------------
Monetary    Friends  6 Lilly           $3,600   12/18/2017  Giving Voice
             of       Street                                 Through
             Lamber   Lambert                                Film
             tville   ville,
             Librar   NJ
             y,       08530
             Inc.
------------------------------------------------------------------------
Monetary    Friends  57                  $300   10/16/2017  Costs
             Of       Mountai                                associated
             Prince   n                                      with
             ton      Avenue                                 Janssen
             Open     Princet                                Cares
             Space    on, NJ                                 Volunteer
                      08540                                  Activity--S
                                                             eptember
                                                             13, 2017
------------------------------------------------------------------------
Monetary    Gateway  4901             $10,000    8/29/2017  Outpatient
             Homes,   Libbie                                 Clinical
             Inc.     Mill                                   Services to
                      East                                   Support
                      Bouleva                                Individuals
                      rd                                     with
                      Suite                                  Schizophren
                      210                                    ia and
                      Richmon                                Schizoaffec
                      d, VA                                  tive
                      23230                                  Disorder
------------------------------------------------------------------------
Monetary    Georgia  246               $2,000    8/21/2017  26th Annual
             Mental   Sycamor                                Statewide
             Health   e St.                                  Consumer
             Consum   Suite                                  Conference
             er       260
             Networ   Decatur
             k        , GA
                      30030
------------------------------------------------------------------------
Monetary    Globalg  1110                $825   11/30/2017  Donation In
             iving    Vermont                                Lieu of
             Founda   Ave. NW                                Gift
             tion,    Suite
             Inc.     550
                      Washing
                      ton, DC
                      20005
------------------------------------------------------------------------
Monetary    Good     38 Elm            $5,000   12/18/2017  Nights of
             Grief,   Street                                 Support--Pr
             Inc.     Morrist                                inceton
                      own, NJ                                Center
                      07960
------------------------------------------------------------------------
Monetary    Greater  102             $150,000     2/2/2017  Greater
             Trento   Barrack                                Trenton
             n        Street                                 Initiative
                      Trenton
                      , NJ
                      08608
------------------------------------------------------------------------
Monetary    Grounds  80                $7,500    12/4/2017  Wellness
             for      Sculpto                                Walks
             Sculpt   rs Way
             ure      Hamilto
                      n, NJ
                      08534
------------------------------------------------------------------------
Monetary    Habitat  530                 $300   12/18/2017  Costs
             for      Route                                  associated
             Humani   38 E                                   with
             ty of    Maple                                  Janssen
             Burlin   Shade,                                 Cares
             gton     NJ                                     Volunteer
             County   08052                                  Activity--O
             and                                             ctober 6,
             Greate                                          2017
             r
             Trento
             n-
             Prince
             ton
------------------------------------------------------------------------
Monetary    Habitat  530                 $300   12/18/2017  Costs
             for      Route                                  associated
             Humani   38 E                                   with
             ty of    Maple                                  Janssen
             Burlin   Shade,                                 Cares
             gton     NJ                                     Volunteer
             County   08052                                  Activity--O
             and                                             ctober 4,
             Greate                                          2017
             r
             Trento
             n-
             Prince
             ton
------------------------------------------------------------------------
Monetary    Habitat  530                 $300   12/18/2017  Costs
             for      Route                                  associated
             Humani   38 E                                   with
             ty of    Maple                                  Janssen
             Burlin   Shade,                                 Cares
             gton     NJ                                     Volunteer
             County   08052                                  Activity--S
             and                                             eptember
             Greate                                          29, 2017
             r
             Trento
             n-
             Prince
             ton
------------------------------------------------------------------------
Monetary    Habitat  530                 $300   12/18/2017  Costs
             for      Route                                  associated
             Humani   38 E                                   with
             ty of    Maple                                  Janssen
             Burlin   Shade,                                 Cares
             gton     NJ                                     Volunteer
             County   08052                                  Activity--S
             and                                             eptember 8,
             Greate                                          2017
             r
             Trento
             n-
             Prince
             ton
------------------------------------------------------------------------
Monetary    Habitat  530               $5,000   12/18/2017  Affordable
             for      Route                                  Homeownersh
             Humani   38 E                                   ip Program
             ty of    Maple
             Burlin   Shade,
             gton     NJ
             County   08052
             and
             Greate
             r
             Trento
             n-
             Prince
             ton
------------------------------------------------------------------------
Monetary    Habitat  31 Oak            $7,500    11/6/2017  Women Build
             for      Avenue,                                and Safe at
             Humani   Suite                                  Home Repair
             ty of    100                                    Clinics
             Greate   Chalfon
             r        t, PA
             Bucks    18914
------------------------------------------------------------------------
Monetary    Heart    1325 G           $30,000   12/22/2017  HRS-WebMD:
             Rhythm   Street                                 Atrial
             Societ   NW,                                    Fibrillatio
             y,       Suite                                  n and How
             Inc.     400                                    to Reduce
                      Washing                                Your Risk
                      ton, DC                                of Stroke
                      20005
------------------------------------------------------------------------
Monetary    Heartla  4750 N.           $7,500    8/11/2017  Pathways
             nd       Sherida                                Home
             Health   n Road
             Outrea   Chicago
             ch       , IL
                      60640
------------------------------------------------------------------------
Monetary    Henders  4740              $7,500    5/31/2017  Helping
             on       North                                  Individuals
             Behavi   State                                  Live Longer
             oral     Road 7                                 (HILL)
             Health   Lauderd
                      ale
                      Lakes,
                      FL
                      33319
------------------------------------------------------------------------
Monetary    HiTOPS,  21                $9,000   12/12/2017  HiTOPS
             Inc.     Wiggins                                Comprehensi
                      Street                                 ve
                      Princet                                Sexuality
                      on, NJ                                 Interventio
                      08540                                  ns for
                                                             Youth-at-
                                                             Risk
------------------------------------------------------------------------
Monetary    HomeFro  1880                $300   10/30/2017  Costs
             nt       Princet                                associated
                      on                                     with
                      Avenue                                 Janssen
                      Lawrenc                                Cares
                      eville,                                Volunteer
                      NJ                                     Activity--O
                      08648                                  ctober 20,
                                                             2017
------------------------------------------------------------------------
Monetary    HomeFro  1880                $300   10/30/2017  Costs
             nt       Princet                                associated
                      on                                     with
                      Avenue                                 Janssen
                      Lawrenc                                Cares
                      eville,                                Volunteer
                      NJ                                     Activity--S
                      08648                                  eptember
                                                             27, 2017
------------------------------------------------------------------------
Monetary    HomeFro  1880                $300   10/30/2017  Costs
             nt       Princet                                associated
                      on                                     with
                      Avenue                                 Janssen
                      Lawrenc                                Cares
                      eville,                                Volunteer
                      NJ                                     Activity--S
                      08648                                  eptember
                                                             20, 2017
------------------------------------------------------------------------
Monetary    HomeFro  1880             $10,000   11/20/2017  Helping
             nt       Princet                                Homeless
                      on                                     Families
                      Avenue                                 Break the
                      Lawrenc                                Cycle of
                      eville,                                Poverty
                      NJ
                      08648
------------------------------------------------------------------------
Monetary    Hopewel  35                  $750   12/12/2017  2018
             l        Princet                                Hopewell
             Elemen   on                                     Elementary
             tary     Avenue                                 School
             School   Hopewel                                Science
             Parent   l, NJ                                  Fair
             Teache   08525
             r
             Organi
             zation
             Inc.
------------------------------------------------------------------------
Monetary    Hopewel  PO Box            $6,446    12/4/2017  Scholarship
             l        553                                    Support:
             Valley   Penning                                $1,000;
             Educat   ton, NJ                                STEM
             ion      08534                                  Education
             Founda                                          and
             tion                                            Sustainabil
                                                             ity
                                                             Education
                                                             at Hopewell
                                                             Elementary
                                                             and Stony
                                                             Brook
                                                             Elementary
                                                             Schools :
                                                             $5446
------------------------------------------------------------------------
Monetary    Hopewel  48                $1,500    12/4/2017  Mobility for
             l        Orchard                                Homebound
             Valley   Ave PO                                 Residents
             Senior   Box 567                                of the
             Founda   Penning                                Hopewell
             tion     ton, NJ                                Valley
                      08534
------------------------------------------------------------------------
Monetary    Hopewel  P.O. Box          $2,525   12/18/2017  Scholarship
             l        159 16                                 Fund
             Valley   Seminar
             Youth    y
             Choral   Avenue,
             e,       Suite C
             Inc.     Hopewel
                      l, NJ
                      08525
------------------------------------------------------------------------
Monetary    Hunterd  7 Lower           $7,500    12/4/2017  Open Studio/
             on Art   Center                                 Open
             Center   Street                                 Hearts:
                      Clinton                                Artistic
                      , NJ                                   Expressions
                      08809                                  and Art
                                                             with Heart
------------------------------------------------------------------------
Monetary    Hunterd  1410              $2,500    11/6/2017  Fundraising
             on       Route                                  event
             County   22 West                                sponsorship
             YMCA     Annanda                                to benefit
                      le, NJ                                 general
                      08801                                  mission of
                                                             organizatio
                                                             n
------------------------------------------------------------------------
Monetary    Hunterd  111 Mine            $300    9/29/2017  Costs
             on       Street                                 associated
             Land     Fleming                                with
             Trust    ton, NJ                                Janssen
                      08822                                  Cares
                                                             Volunteer
                                                             Activity--S
                                                             eptember
                                                             14, 2017
------------------------------------------------------------------------
Monetary    Hunterd  111 Mine          $2,500    12/4/2017  Promotion
             on       Street                                 and
             Land     Fleming                                Protection
             Trust    ton, NJ                                of
                      08822                                  Preserves
------------------------------------------------------------------------
Monetary    Interfa  3635             $15,000   10/30/2017  Neighbors
             ith      Quakerb                                Helping
             Caregi   ridge                                  Neighbors
             vers     Road,
             Trento   Suite
             n,       #16
             Inc.     Hamilto
                      n, NJ
                      08619
------------------------------------------------------------------------
Monetary    Isles,   10 Wood             $300    9/29/2017  Costs
             Inc.     Street                                 associated
                      Trenton                                with
                      , NJ                                   Janssen
                      08618                                  Cares
                                                             Volunteer
                                                             Activity--S
                                                             eptember
                                                             20, 2017
------------------------------------------------------------------------
Monetary    Isles,   10 Wood           $9,000   12/12/2017  Trenton
             Inc.     Street                                 Healthy
                      Trenton                                Homes
                      , NJ
                      08618
------------------------------------------------------------------------
Monetary    Jewish   707                 $300    9/29/2017  Costs
             Family   Alexand                                associated
             and      er Road                                with
             Childr   Suite                                  Janssen
             en's     102                                    Cares
             Servic   Princet                                Volunteer
             e of     on, NJ                                 Activity--S
             Greate   08540                                  eptember
             r                                               28, 2017
             Mercer
             County
------------------------------------------------------------------------
Monetary    Jewish   707              $15,000   12/18/2017  Senior
             Family   Alexand                                Outreach
             and      er Road                                Service
             Childr   Suite                                  (SOS) PLUS
             en's     102                                    ($12,000);
             Servic   Princet                                Caregiver
             e of     on, NJ                                 Program
             Greate   08540                                  ($3,000)
             r
             Mercer
             County
------------------------------------------------------------------------
Monetary    Jewish   150-A             $5,000   10/30/2017  Expanding
             Family   West                                   Horizons
             Servic   High
             e of     St.
             Somers   Somervi
             et       lle, NJ
             Hunter   08876
             don
             and
             Warren
             Counti
             es
             Inc.
------------------------------------------------------------------------
Monetary    Johnson  One           $5,500,000     7/3/2017  General
             &        Johnson                                mission
             Johnso   &                                      support
             n        Johnson
             Patien   Plaza
             t        Kilmer
             Assist   Square
             ance     Suite
             Founda   130 New
             tion     Brunswi
             Inc.     ck, NJ
                      08933
------------------------------------------------------------------------
Monetary    Johnson  One          $15,500,000    9/28/2017  General
             &        Johnson                                mission
             Johnso   &                                      support
             n        Johnson
             Patien   Plaza
             t        Kilmer
             Assist   Square
             ance     Suite
             Founda   130 New
             tion     Brunswi
             Inc.     ck, NJ
                      08933
------------------------------------------------------------------------
Monetary    Johnson  One           $2,400,000   12/18/2017  General
             &        Johnson                                mission
             Johnso   &                                      support
             n        Johnson
             Patien   Plaza
             t        Kilmer
             Assist   Square
             ance     Suite
             Founda   130 New
             tion     Brunswi
             Inc.     ck, NJ
                      08933
------------------------------------------------------------------------
Monetary    Junior   360 Pear          $7,150   10/30/2017  STEMCivics
             Achiev   Blossom                                High School
             ement    Drive                                  Heroes JA
             of New   Edison,                                Day
             Jersey   NJ
                      08837
------------------------------------------------------------------------
Monetary    Kidsbri  999              $10,000   10/16/2017  Bullying
             dge,     Lower                                  Prevention
             Inc.     Ferry                                  and
                      Rd                                     Diversity
                      Ewing,                                 Appreciatio
                      NJ                                     n Life
                      08628                                  Skills
                                                             Program for
                                                             At-Risk
                                                             Middle
                                                             School
                                                             Students in
                                                             Trenton
------------------------------------------------------------------------
Monetary    Kidsbri  999               $9,500     2/1/2017  Bullying
             dge,     Lower                                  Prevention
             Inc.     Ferry                                  and
                      Rd                                     Diversity
                      Ewing,                                 Appreciatio
                      NJ                                     n Life
                      08628                                  Skills
                                                             Program for
                                                             At-Risk
                                                             Elementary/
                                                             Middle
                                                             School
                                                             Students in
                                                             Trenton
------------------------------------------------------------------------
Monetary    Latin    669               $5,000   12/12/2017  FUTURO
             Americ   Chamber
             an       s
             Legal    Street,
             Defens   Suite B
             e and    Trenton
             Educat   , NJ
             ional    08611
             Fund
             Inc.
------------------------------------------------------------------------
Monetary    Leyden   10001 W          $25,000   12/12/2017  Transitional
             Family   Grand                                  Living
             Servic   Ave                                    Program
             e and    Frankli                                Expansion
             Mental   n Park,
             Health   IL
             Center   60131
------------------------------------------------------------------------
Monetary    LifeTie  2205              $8,000   12/18/2017  Programs to
             s,       Penning                                Serve
             Inc.     ton                                    Chronically
                      Road                                   Ill and
                      Ewing,                                 Abused and
                      NJ                                     Neglected
                      08638                                  Older Youth
                                                             Transitioni
                                                             ng Into
                                                             Adulthood.
------------------------------------------------------------------------
Monetary    Literac  100               $5,000   12/12/2017  Women
             y New    Menlo                                  Empowered
             Jersey   Park                                   (WE)
             , Inc.   Drive,
                      Suite
                      314
                      Edison,
                      NJ
                      08837
------------------------------------------------------------------------
Monetary    Literac  120               $4,000   12/12/2017  Health
             y        Findern                                Literacy
             Volunt   e                                      for All
             eers     Avenue
             of       Box 7
             Somers   Bridgew
             et       ater,
             County   NJ
                      08807
------------------------------------------------------------------------
Monetary    Main     8                 $1,000    5/31/2017  Crisis
             Street   Marcell                                Interventio
             Counse   a                                      n Team
             ling     Avenue                                 Training
             Center   West                                   for Essex
                      Orange,                                County Law
                      NJ                                     Enforcement
                      07052
------------------------------------------------------------------------
Monetary    Main     8                 $5,000    6/12/2017  Accessible
             Street   Marcell                                Mental
             Counse   a                                      Health Care
             ling     Avenue                                 for
             Center   West                                   Individuals
                      Orange,                                Suffering
                      NJ                                     From
                      07052                                  Schizoaffec
                                                             tive
                                                             Disorder
------------------------------------------------------------------------
Monetary    Massach  15                $3,500     2/6/2017  Changing
             usetts   Vernon                                 Minds and
             Clubho   Street                                 Expanding
             use      Waltham                                Employment
             Coalit   , MA                                   Campaign
             ion      02453
------------------------------------------------------------------------
Monetary    McCarte  91               $10,000   11/20/2017  OnStage
             r        Univers                                Seniors: A
             Theatr   ity                                    Community
             e        Place                                  Project of
             Center   Princet                                McCarter
                      on, NJ                                 Theatre
                      08540
------------------------------------------------------------------------
Monetary    Meals    320                 $300    9/29/2017  Costs
             on       Hollowb                                associated
             Wheels   rook                                   with
             of       Drive                                  Janssen
             Trento   Ewing,                                 Cares
             n        NJ                                     Volunteer
             Ewing    08638                                  Activity--O
                                                             ctober 4,
                                                             2017
------------------------------------------------------------------------
Monetary    Meals    320              $15,000    11/6/2017  Subsidized
             on       Hollowb                                Meal
             Wheels   rook                                   Program
             of       Drive                                  (SMP)
             Trento   Ewing,
             n        NJ
             Ewing    08638
------------------------------------------------------------------------
Monetary    Mental   500              $50,000    9/21/2017  General
             Health   Montgom                                mission
             Americ   ery St.                                support
             a        Suite
                      820
                      Alexand
                      ria, VA
                      22314
------------------------------------------------------------------------
Monetary    Mental   500             $100,000   12/12/2017  Social Self-
             Health   Montgom                                Directed
             Americ   ery St.                                Care (SSDC)
             a        Suite
                      820
                      Alexand
                      ria, VA
                      22314
------------------------------------------------------------------------
Monetary    Mental   2211              $7,500   10/20/2017  Mental
             Health   Norfolk                                Health
             Americ   , Suite                                Advocacy
             a of     810
             Greate   Houston
             r        , TX
             Housto   77098
             n
------------------------------------------------------------------------
Monetary    Mental   2323 W           $10,000    5/24/2017  Get
             Health   5th                                    Connected
             Americ   Ave.
             a of     Suite
             Frankl   160
             in       Columbu
             County   s, OH
                      43204
------------------------------------------------------------------------
Monetary    Mental   1210 San          $2,500    4/24/2017  Mental
             Health   Antonio                                Health
             Americ   , Suite                                Education
             a of     200                                    and
             Texas    Austin,                                Advocacy
                      TX                                     Campaign
                      78701
------------------------------------------------------------------------
Monetary    Mental   100 W.            $2,000   10/13/2017  Community
             Health   10th                                   Mental
             Associ   St.                                    Health
             ation    Ste.                                   Conference
             in       600                                    2017
             Delawa   Wilming
             re       ton, DE
                      19801
------------------------------------------------------------------------
Monetary    Mental   100 W.            $1,000    10/3/2017  E-Racing the
             Health   10th                                   Blues for
             Associ   St.                                    Mental
             ation    Ste.                                   Health Run/
             in       600                                    Walk
             Delawa   Wilming
             re       ton, DE
                      19801
------------------------------------------------------------------------
Monetary    Mental   617               $2,500    5/31/2017  Operating
             Health   Garden                                 Support for
             Associ   Street                                 the
             ation    Santa                                  Fellowship
             in       Barbara                                Club
             Santa    , CA
             Barbar   93101
             a
             County
------------------------------------------------------------------------
Monetary    Mental   3701              $7,500    5/31/2017  ParentVOICE
             Health   Latrobe
             Associ   Drive,
             ation    Suite
             of       140
             Centra   Charlot
             l        te, NC
             Caroli   28211
             nas,
             Inc.
------------------------------------------------------------------------
Monetary    Mental   580               $1,000    5/31/2017  Get On Your
             Health   White                                  Mat For
             Associ   Plains                                 Mental
             ation    Road                                   Health
             of       Suite
             Westch   510
             ester    Tarryto
                      wn, NY
                      10591
------------------------------------------------------------------------
Monetary    Mental   3809             $12,500    8/30/2017  Outreach and
             Illnes   Rosewoo                                Behavioral
             s        d Drive                                Healthcare
             Recove   P.O.                                   for
             ry       Box                                    Homeless
             Center   4246                                   Individuals
             , Inc.   Columbi                                with Mental
                      a, SC                                  Illness
                      29240
------------------------------------------------------------------------
Monetary    Mercer   1001             $15,000   12/19/2017  Addressing
             Allian   Spruce                                 Young Adult
             ce to    Street                                 Homelessnes
             End      Suite                                  s, through
             Homele   205                                    planning,
             ssness   Trenton                                assertive
                      , NJ                                   engagement,
                      08638                                  housing,
                                                             and
                                                             healthcare
                                                             access
------------------------------------------------------------------------
Monetary    Mercer   P.O. Box          $6,500    11/6/2017  Miscellaneou
             County   17202                                  s medical
             Commun   Trenton                                equipment
             ity      , NJ                                   ($1,000),
             Colleg   08690                                  and work
             e                                               study
             Founda                                          student
             tion                                            mentors
                                                             ($3,500) to
                                                             provide
                                                             academic
                                                             enrichment
                                                             for health
                                                             profession
                                                             students
                                                             success
------------------------------------------------------------------------
Monetary    Mercer   3 Creek           $1,000   11/20/2017  Mercer
             Scienc   Rim                                    Science
             e And    Drive                                  Fair 2018
             Engine   Titusvi
             ering    lle, NJ
             Club     08560
------------------------------------------------------------------------
Monetary    Mercer   151                 $300    8/24/2017  Costs
             Street   Mercer                                 associated
             Friend   Street                                 with
             s        Trenton                                Janssen
                      , NJ                                   Cares
                      08611                                  Volunteer
                                                             Activity--O
                                                             ctober 4,
                                                             2017
------------------------------------------------------------------------
Monetary    Mercer   151                 $300    8/24/2017  Costs
             Street   Mercer                                 associated
             Friend   Street                                 with
             s        Trenton                                Janssen
                      , NJ                                   Cares
                      08611                                  Volunteer
                                                             Activity--S
                                                             eptember
                                                             14, 2017
------------------------------------------------------------------------
Monetary    Mercer   151              $25,000   10/30/2017  Mercer
             Street   Mercer                                 Street
             Friend   Street                                 Friends
             s        Trenton                                Food Bank
                      , NJ
                      08611
------------------------------------------------------------------------
Monetary    Middle   P.O. Bos         $15,000   10/16/2017  Outreach
             Earth    8045                                   Program and
                      520                                    Community
                      North                                  Youth
                      Bridge                                 Center
                      Street
                      Bridgew
                      ater,
                      NJ
                      08807
------------------------------------------------------------------------
Monetary    MIDJers  423               $5,000    8/16/2017  City of
             ey       Rivervi                                Trenton--Su
             Center   ew                                     mmer Youth
             for      Plaza                                  Employment
             Econom   Trenton                                Program
             ic       , NJ
             Develo   08611
             pment
------------------------------------------------------------------------
Monetary    Midland  60                $6,500    8/16/2017  Midland
             Adult    Industr                                Meals on
             Servic   ial                                    Wheels
             es,      Parkway                                Employment
             Inc.     P.O.                                   Training
                      Box                                    Program
                      5026
                      North
                      Branch,
                      NJ
                      08876
------------------------------------------------------------------------
Monetary    Midland  94                  $300    9/13/2017  Costs
             Founda   Reading                                associated
             tion     ton                                    with
                      Road                                   Janssen
                      P.O.                                   Cares
                      Box                                    Volunteer
                      5026                                   Activity--O
                      North                                  ctober 3,
                      Branch,                                2017
                      NJ
                      08876
------------------------------------------------------------------------
Monetary    Millhil  101               $5,000   10/30/2017  Trenton Area
             l        Oakland                                Stakeholder
             Child    Street                                 s
             and      Trenton
             Family   , NJ
             Develo   08618
             pment
------------------------------------------------------------------------
Monetary    Millhil  101              $15,000   10/30/2017  Millhill
             l        Oakland                                Trenton
             Child    Street                                 PEERS
             and      Trenton
             Family   , NJ
             Develo   08618
             pment
------------------------------------------------------------------------
Monetary    Morven   55                $5,000    11/6/2017  Internships
             Museum   Stockto                                for At-Risk
             and      n                                      Youth
             Garden   Street
                      Princet
                      on, NJ
                      08540
------------------------------------------------------------------------
Monetary    Mount    73 North         $15,000   10/27/2017  In Home
             Carmel   Clinton                                Nursing
             Guild    Avenue                                 Services
                      Trenton
                      , NJ
                      08609
------------------------------------------------------------------------
Monetary    NAMI     7500              $3,000    10/4/2017  Educational
                      Greenwo                                and
                      od Ave                                 Training
                      N                                      Programs
                      Seattle
                      , WA
                      98103
------------------------------------------------------------------------
Monetary    NAMI--C  1904              $2,500    8/14/2017  Education
             VA       Byrd                                   and support
             Centra   Avenue                                 programs
             l        Suite                                  and
             Virgin   207                                    HelpLine
             ias      (POB
             Voice    18086)
             On       Richmon
             Mental   d, VA
             Illnes   23230
             s
------------------------------------------------------------------------
Monetary    NAMI     107               $5,000    8/29/2017  NAMI Ending
             Geauga   South                                  the Silence
             County   Street;
                      # 5
                      Chardon
                      , OH
                      44024
------------------------------------------------------------------------
Monetary    NAMI     107               $2,000    8/29/2017  NAMI
             Geauga   South                                  Connection
             County   Street;                                and Peer-to-
                      # 5                                    Peer
                      Chardon                                Collaborati
                      , OH                                   on A Peer-
                      44024                                  led Support
                                                             and
                                                             Education
                                                             Program
------------------------------------------------------------------------
Monetary    NAMI     4161 NW           $1,000    5/31/2017  NAMIWalks
             Browar   5 St.                                  Broward
             d        Suite                                  County
             County   203
             , Inc.   Plantat
                      ion, FL
                      33317
------------------------------------------------------------------------
Monetary    NAMI     8324              $1,000    3/20/2017  NAMI CCNS 5k
             Cook     Skokie                                 Run/Walk
             County   Blvd                                   2017
             North    Skokie,
             Suburb   IL
             an       60077
------------------------------------------------------------------------
Monetary    NAMI     2400 W.           $1,000    3/20/2017  2017
             Delawa   4th                                    NAMIWalks
             re       Street                                 Delaware
                      Wilming
                      ton, DE
                      19805
------------------------------------------------------------------------
Monetary    NAMI     P.O. Box          $2,500    10/4/2017  Support
             Hernan   5613                                   Services
             do       Spring                                 and CARE
                      Hill,                                  Line
                      FL
                      34609
------------------------------------------------------------------------
Monetary    NAMI     1235             $10,000   10/16/2017  Education
             Mercer   Whiteho                                and Support
             NJ       rse                                    Programs
                      Mercerv                                for Mental
                      ille                                   Health
                      Road                                   Consumers
                      Bldg.                                  and Family
                      C,                                     Members
                      Suite
                      303
                      Hamilto
                      n, NJ
                      08619
------------------------------------------------------------------------
Monetary    NAMI     1235              $2,500     3/8/2017  Silver
             Mercer   Whiteho                                sponsor
             NJ       rse                                    2017
                      Mercerv                                NAMIWalks
                      ille                                   Mercer
                      Road                                   County, NJ
                      Bldg.                                  May 6, 2017
                      C,
                      Suite
                      303
                      Hamilto
                      n, NJ
                      08619
------------------------------------------------------------------------
Monetary    NAMI     85 N.             $1,000    10/5/2017  NAMIWalks NH
             New      State                                  2017
             Hampsh   Street
             ire      Concord
                      , NH
                      03301
------------------------------------------------------------------------
Monetary    NAMI     1538              $7,500    8/29/2017  1-on-1
             New      Louisia                                Education
             Orlean   na Ave.                                for People
             s        New                                    Living with
                      Orleans                                Schizoaffec
                      , LA                                   tive
                      70115                                  Disorder/
                                                             Schizophren
                                                             ia and
                                                             Their Loved
                                                             Ones/
                                                             Caregivers
------------------------------------------------------------------------
Monetary    NAMI of  115               $8,000    10/3/2017  Living Room
             DuPage   North                                  Program
             County   County
             Illino   Farm
             is       Road
                      Wheaton
                      , IL
                      60187
------------------------------------------------------------------------
Monetary    NAMI of  2701              $3,000   10/13/2017  Compeer
             Johnso   Rochest                                connects
             n        er Ave.                                with Local
             County   Iowa                                   Businesses
             dba      City,                                  to Increase
             Compee   IA                                     Volunteeris
             r of     52245                                  m and
             Johnso                                          Visibility
             n
             County
------------------------------------------------------------------------
Monetary    NAMI of  One               $3,000    9/29/2017  NAMI Peer-to-
             Lake     Victori                                Peer
             County   a Sq.,                                 Recovery
                      Ste.                                   Education
                      260                                    Program
                      Painesv
                      ille,
                      OH
                      44077
------------------------------------------------------------------------
Monetary    NAMI of  One               $1,500    8/11/2017  NAMI Lake
             Lake     Victori                                County
             County   a Sq.,                                 Strides for
                      Ste.                                   Awareness
                      260                                    NAMI Walk
                      Painesv
                      ille,
                      OH
                      44077
------------------------------------------------------------------------
Monetary    NAMI of  100 W,            $1,000    1/31/2017  Bronze
             PA       Main                                   sponsor
             Montgo   St.                                    NAMIWalks
             mery     Suite                                  Greater
             County   204                                    Philadelphi
                      Lansdal                                a May 6,
                      e, PA                                  2017
                      19446
------------------------------------------------------------------------
Monetary    NAMI of  4055              $3,500    9/29/2017  Hope for
             Southw   Executi                                Recovery
             est      ve Park
             Ohio     Drive,
                      Suite
                      450
                      Cincinn
                      ati, OH
                      45241
------------------------------------------------------------------------
Monetary    NAMI     3037 NW           $1,000     5/9/2017  NAMI Walks
             Oklaho   63RD,                                  Oklahoma
             ma       SUITE
                      104W
                      Oklahom
                      a City,
                      OK
                      73116
------------------------------------------------------------------------
Monetary    NAMI     1750 S.           $1,000     5/4/2017  2017
             St.      Brentwo                                NAMIWALKS
             Louis    od                                     St. Louis
                      Blvd.
                      Suite
                      511 St.
                      Louis,
                      MO
                      63144
------------------------------------------------------------------------
Monetary    NAMI     P.O. Box          $1,000     9/7/2017  13th Annual
             Summit   462,                                   NAMIWalks
             County   Cuyahog                                Summit
                      a Falls                                County 2017
                      OH
                      44222
                      Akron,
                      OH
                      44311
------------------------------------------------------------------------
Monetary    NAMI     5251              $1,000    5/31/2017  NAMIWalks
             Ventur   Verdugo                                event in
             a        Way, #K                                Ventura
             County   P.O.                                   County, CA
                      Box
                      1613
                      Camaril
                      lo, CA
                      93011
------------------------------------------------------------------------
Monetary    NAMI     217               $1,000    8/30/2017  NAMIWalks
             Waukes   Wiscons                                Waukesha
             ha       in Ave
                      Suite
                      300
                      Waukesh
                      a, WI
                      53186
------------------------------------------------------------------------
Monetary    NAMI     217               $1,000    8/11/2017  Crisis
             Waukes   Wiscons                                Interventio
             ha       in Ave                                 n Training
                      Suite                                  for Law
                      300                                    Enforcement
                      Waukesh
                      a, WI
                      53186
------------------------------------------------------------------------
Monetary    Nationa  1851              $2,500    5/31/2017  2017 NAMI
             l        Heritag                                California
             Allian   e Way,                                 Annual
             ce for   Suite                                  Conference
             the      150
             Mental   Sacrame
             ly Ill   nto, CA
                      95815
------------------------------------------------------------------------
Monetary    Nationa  576               $1,500    3/20/2017  2017 NAMI
             l        Farming                                Connecticut
             Allian   ton                                    Walk
             ce for   Avenue
             the      Hartfor
             Mental   d, CT
             ly Ill   06105
------------------------------------------------------------------------
Monetary    Nationa  5095              $1,000    3/20/2017  NAMIWalks/
             l        Murphy                                 Run San
             Allian   Canyon                                 Diego
             ce for   Road,                                  County
             the      Suite
             Mental   320 San
             ly Ill   Diego,
                      CA
                      92123
------------------------------------------------------------------------
Monetary    Nationa  1562              $1,000    1/31/2017  Bronze
             l        Route                                  sponsor
             Allian   130                                    2017
             ce for   North                                  NAMIWalks
             the      Brunswi                                New Jersey
             Mental   ck, NJ                                 ``Building
             ly Ill   08902                                  Better
                                                             Lives''--Ma
                                                             y 13, 2017
------------------------------------------------------------------------
Monetary    Nationa  800               $3,500    8/29/2017  Project ADD
             l        Transfe                                Advocating
             Allian   r Road                                 for Dual
             ce for   #31 St.                                Diagnosis
             the      Paul,
             Mental   MN
             ly Ill   55114
------------------------------------------------------------------------
Monetary    Nationa  3440              $1,000    4/21/2017  NAMIWalks
             l        Viking                                 Northern
             Allian   Drive,                                 California
             ce for   Suite
             the      104A
             Mental   Sacrame
             ly Ill   nto, CA
                      95827
------------------------------------------------------------------------
Monetary    Nationa  PO Box            $1,000    8/29/2017  NAMI
             l        550039                                 Birmingham
             Allian   Birming                                2017 Walk
             ce for   ham, AL                                for Mental
             the      35255-                                 Health
             Mental   0039
             ly Ill
------------------------------------------------------------------------
Monetary    Nationa  3803 N.          $50,000    10/3/2017  General
             l        Fairfax                                mission
             Allian   Drive                                  support
             ce for   Suite
             the      100
             Mental   Arlingt
             ly Ill   on, VA
                      22203
------------------------------------------------------------------------
Monetary    Nationa  1801 W            $8,000   11/16/2017  Honest,
             l        Warner                                 Open,
             Allian   Ave,                                   Proud:
             ce for   Suite                                  Addressing
             the      202                                    Stigma
             Mental   Chicago                                Among the
             ly Ill   , IL                                   Incarcerate
                      60613                                  d
                                                             Population
------------------------------------------------------------------------
Monetary    Nationa  1562,             $2,500   10/13/2017  Annual
             l        Route                                  Conference-
             Allian   130                                    -Honoring
             ce for   North                                  The Past,
             the      Brunswi                                Embracing
             Mental   ck, NJ                                 The
             ly Ill   08902                                  Present,
                                                             Looking To
                                                             The Future
------------------------------------------------------------------------
Monetary    Nationa  3200 S.           $1,000    1/31/2017  Bronze
             l        3rd                                    sponsor
             Allian   Street,                                2017 NAMI
             ce for   Unit 6                                 Walk of
             the      Milwauk                                Greater
             Mental   ee, WI                                 Milwaukee--
             ly Ill   53207                                  May 20,
                                                             2017
------------------------------------------------------------------------
Monetary    Nationa  218 West          $5,000   10/19/2017  NAMI
             l        Lawrenc                                Illinois--G
             Allian   e                                      rassroots
             ce for   Springf                                Advocacy
             the      ield,                                  Capacity
             Mental   IL                                     Project
             ly Ill   62704
------------------------------------------------------------------------
Monetary    Nationa  P.O. Box          $1,000   10/11/2017  Mental
             l        4096                                   Health
             Allian   Alvin,                                 Education
             ce for   TX                                     Conference-
             the      77512                                  -May 2018
             Mental
             ly Ill
------------------------------------------------------------------------
Monetary    Nationa  3803 N.          $75,000   12/18/2017  NAMI 2018
             l        Fairfax                                CIT/
             Allian   Drive                                  Criminal
             ce for   Suite                                  Justice
             the      100                                    Enhancement
             Mental   Arlingt                                Initiative
             ly Ill   on, VA
                      22203
------------------------------------------------------------------------
Monetary    Nationa  3803 N.          $50,000   12/18/2017  NAMI
             l        Fairfax                                HelpLine
             Allian   Drive                                  2018
             ce for   Suite
             the      100
             Mental   Arlingt
             ly Ill   on, VA
                      22203
------------------------------------------------------------------------
Monetary    Nationa  99 Pine           $5,000   10/27/2017  Intervention
             l        St.                                    ,
             Allian   Suite                                  Engagement,
             ce for   105                                    Implementat
             the      Albany,                                ion: Three
             Mental   NY                                     Pronged
             ly Ill   12207                                  Approach to
                                                             Sustainable
                                                             Mental
                                                             Health
                                                             Recovery
------------------------------------------------------------------------
Monetary    Nationa  P.O. Box          $1,000   10/19/2017  12th Annual
             l        24128                                  NAMI
             Allian   117                                    Lowcountry
             ce for   William                                Walk
             the      Hilton
             Mental   Parkway
             ly Ill   , Suite
                      K
                      Hilton
                      Head
                      Island,
                      SC
                      29925
------------------------------------------------------------------------
Monetary    Nationa  4701 SE           $2,500    8/23/2017  NAMI Oregon
             l        24th                                   Mental
             Allian   Ave.,                                  Health
             ce for   Suite E                                Education
             the      Portlan                                and Support
             Mental   d, OR                                  Programs
             ly Ill   97202                                  for
                                                             Recovery
                                                             and
                                                             Wellness
------------------------------------------------------------------------
Monetary    Nationa  10630             $1,000     5/9/2017  2017 NAMI
             l        Little                                 Walks
             Allian   Patuxen                                Maryland
             ce for   t
             the      Parkway
             Mental   Columbi
             ly Ill   a, MD
                      21044
------------------------------------------------------------------------
Monetary    Nationa  2059              $2,000    5/31/2017  Dane County
             l        Atwood                                 Crisis
             Allian   Ave,                                   Interventio
             ce for   Floor 4                                n Team
             the      Madison                                (CIT)
             Mental   , WI                                   Program
             ly Ill   53704
------------------------------------------------------------------------
Monetary    Nationa  2059              $1,000    5/31/2017  NAMIWalks
             l        Atwood                                 Dane County
             Allian   Ave,                                   2017
             ce for   Floor 4
             the      Madison
             Mental   , WI
             ly Ill   53704
------------------------------------------------------------------------
Monetary    Nationa  309 West          $1,000     5/5/2017  NAMI Walks
             l        Millbro                                North
             Allian   ok Rd,                                 Carolina
             ce for   Suite
             the      121
             Mental   Raleigh
             ly Ill   , NC
                      27609
------------------------------------------------------------------------
Monetary    Nationa  2012              $5,000    8/29/2017  Mental
             l        West                                   Illness
             Allian   25th                                   Peer
             ce for   Street,                                Support and
             the      #600                                   Education
             Mental   Clevela
             ly       nd, OH
             Ill--G   44113
             reater
             Clevel
             and
------------------------------------------------------------------------
Monetary    Nationa  2012              $1,000    8/29/2017  NAMIWalks
             l        West                                   2017
             Allian   25th
             ce for   Street,
             the      #600
             Mental   Clevela
             ly       nd, OH
             Ill--G   44113
             reater
             Clevel
             and
------------------------------------------------------------------------
Monetary    Nationa  505 8th           $1,000     5/4/2017  NAMIWalks
             l        Avenue,                                NYC 2017
             Allian   Ste.                                   Walk/Run
             ce for   1103                                   for Mental
             the      New                                    Health
             Mental   York,
             ly Ill   NY
             of New   10018
             York
             City
------------------------------------------------------------------------
Monetary    Nationa  154               $1,000    10/2/2017  NAMIWalks
             l        Waterma                                Rhode
             Allian   n St.,                                 Island 2017
             ce of    Suite
             Mental   5B
             Illnes   Provide
             s        nce, RI
                      02906
------------------------------------------------------------------------
Monetary    Nationa  5963              $1,000    8/11/2017  NAMIWalks
             l        Boymel                                 Butler
             Allian   Dr.                                    County
             ce on    Fairfie
             Mental   ld, OH
             Illnes   45014
             s
------------------------------------------------------------------------
Monetary    Nationa  P.O. Box          $6,000    4/21/2017  General
             l Art    350891                                 mission
             Exhibi   Miami,                                 support
             tions    FL
             of the   33135
             Mental
             ly
             Ill,
             Inc.
------------------------------------------------------------------------
Monetary    Nationa  8321 Old         $30,000   12/28/2017  TakeIt2Heart
             l        Courtho                                TM--An e-
             Blood    use Rd.                                Health
             Clot     Suite                                  Anticoagula
             Allian   255 110                                tion
             ce       N.                                     Management
                      Washing                                Education
                      ton                                    Program
                      St.,                                   Focused on
                      Suite                                  AFib
                      255                                    Awareness
                      Rockvil                                and
                      le, MD                                 Lifestyle
                      20850                                  Issues
                      Vienna,                                Encountered
                      VA                                     by AFib
                      22182                                  Patients
                                                             and their
                                                             Non-Medical
                                                             Caregivers
------------------------------------------------------------------------
Monetary    Nationa  1100             $10,000   10/25/2017  2017 Science
             l        17th                                   and
             Coalit   Street,                                Leadership
             ion      NW                                     Symposium
             for      Suite
             Women    500
             with     Washing
             Heart    ton, DC
             Diseas   20036
             e,
             Inc.
------------------------------------------------------------------------
Monetary    Nationa  1400 K           $85,000   12/18/2017  Medication
             l        Street                                 Adherence
             Counci   NW                                     Learning
             l for    Washing                                Community
             Behavi   ton, DC
             oral     20005
             Health
------------------------------------------------------------------------
Monetary    Nationa  1400 K           $85,000   12/18/2017  Policy
             l        Street                                 Action
             Counci   NW                                     Center
             l for    Washing
             Behavi   ton, DC
             oral     20005
             Health
------------------------------------------------------------------------
Monetary    Nationa  949 West          $7,500    12/4/2017  ACE and STEM
             l        State                                  Program,
             Junior   St.                                    plus tennis
             Tennis   Trenton
             and      , NJ
             Learni   08618
             ng of
             Trento
             n
------------------------------------------------------------------------
Monetary    Nationa  9707 E           $25,000   12/22/2017  National
             l        Easter                                 Stroke
             Stroke   Lane,                                  Awareness
             Associ   Suite B                                Month
             ation    Centenn
                      ial, CO
                      80112
------------------------------------------------------------------------
Monetary    New      275 Rt.           $4,000    5/24/2017  NJPC
             Jersey   10 East                                Professiona
             Parent   Suite                                  l Parent
             s        220-414                                Advocacy
             Caucus   Succasu                                Training
                      nna, NJ
                      07876
------------------------------------------------------------------------
Monetary    North    368              $10,000   12/22/2017  NATF Spring
             Americ   Boylsto                                Patient
             an       n St.                                  Program
             Thromb   Brookli
             osis     ne, MA
             Forum    02445
------------------------------------------------------------------------
Monetary    North    368              $20,000   12/22/2017  VTE Support
             Americ   Boylsto                                Group
             an       n St.                                  Project
             Thromb   Brookli
             osis     ne, MA
             Forum    02445
------------------------------------------------------------------------
Monetary    Northea  2900              $2,500     4/4/2017  Day of
             st       Conner                                 Restoration
             Guidan   Avenue,
             ce       Buildin
             Center   g A
                      Detroit
                      , MI
                      48215
------------------------------------------------------------------------
Monetary    Passage  P.O. Box          $7,500    12/4/2017  Support for
             Theatr   967                                    Passage
             e        Trenton                                Theatre's
             Compan   , NJ                                   Education
             y,       08605                                  programming
             Inc.                                            the State
                                                             Street
                                                             Project
------------------------------------------------------------------------
Monetary    Peggie   93                   $75     3/9/2017  Employee
             and      Patrici                                directed
             Paul     a Place                                donation in
             Shevli   Media,                                 lieu of
             n        PA                                     company
             Family   19063                                  holiday
             Founda                                          gift
             tion
------------------------------------------------------------------------
Monetary    PEI      231              $17,500   10/16/2017  Comprehensiv
             Kids     Lawrenc                                e Juvenile
                      e Road                                 Offenders
                      Lawrenc                                Outreach
                      eville,                                Services
                      NJ                                     (CJOOS)
                      08648                                  Program
------------------------------------------------------------------------
Monetary    PEI      231                 $300    9/29/2017  Costs
             Kids     Lawrenc                                associated
                      e Road                                 with
                      Lawrenc                                Janssen
                      eville,                                Cares
                      NJ                                     Volunteer
                      08648                                  Activity--O
                                                             ctober 13,
                                                             2017
------------------------------------------------------------------------
Monetary    People   295               $2,500    12/5/2017  Reading
             And      Eggerts                                Deeply in
             Storie   Crossin                                Community:
             s--Gen   g Road                                 A
             te Y     Lawrenc                                Literature
             Cuento   eville,                                Project for
             s,       NJ                                     Mercer
             Inc.     08648                                  County
                                                             Youth and
                                                             Seniors
------------------------------------------------------------------------
Monetary    PlanSma  118 West          $3,500     3/8/2017  2017
             rt NJ    State                                  Corporate
                      PlanSma                                membership
                      rt NJ                                  renewal
                      Trenton                                donation to
                      , NJ                                   support
                      08608                                  efforts
                                                             around
                                                             sound land
                                                             use
                                                             planning
------------------------------------------------------------------------
Monetary    Princet  P.O. Box          $2,500    12/4/2017  Afterschool
             on       134 190                                Music
             Girl     Nassau                                 Outreach
             Choir    Street                                 Program
                      Princet
                      on, NJ
                      08542
------------------------------------------------------------------------
Monetary    Princet  45                $4,000   12/12/2017  Supporting
             on       Stockto                                Family
             Senior   n St                                   Caregivers
             Resour   Princet
             ce       on, NJ
             Center   08540
------------------------------------------------------------------------
Monetary    Princet  P.O. Box          $4,000   12/12/2017  PSO BRAVO!
             on       250,                                   TRENTON
             Sympho   575                                    Youth
             ny       Ewing                                  Education
             Orches   Street                                 Initiative
             tra      Princet
                      on, NJ
                      08540
------------------------------------------------------------------------
Monetary    Princet  13                $7,500    12/5/2017  Summer
             on-      Roszel                                 Bridge
             Blairs   Road                                   2018--Trent
             town     Suite                                  on
             Center   C204A
             , Inc.   Princet
                      on, NJ
                      08540
------------------------------------------------------------------------
Monetary    Printma  440              $15,000   12/18/2017  Combat Paper
             king     River                                  NJ
             Center   Road
             of New   Branchb
             Jersey   urg, NJ
                      08876
------------------------------------------------------------------------
Monetary    Public   825               $7,500    7/25/2017  NJTV's In
             Media    Eighth                                 Your
             NJ,      Avenue                                 Neighborhoo
             Inc.     New                                    d Trenton
                      York,
                      NY
                      10019
------------------------------------------------------------------------
Monetary    Rainier  12020               $750    4/20/2017  Employee
             Therap   123rd                                  directed
             eutic    Ave. SE                                donation in
             Riding   Rainier                                lieu of
                      Rainier                                company
                      , WA                                   holiday
                      98576                                  gift
------------------------------------------------------------------------
Monetary    Raritan  P.O. Box          $7,000    12/5/2017  WaterWays
             Headwa   273                                    Environment
             ters     Gladsto                                al
             Associ   ne, NJ                                 Education
             ation    07934                                  Program
------------------------------------------------------------------------
Monetary    Raritan  118              $20,000   10/30/2017  Nursing
             Valley   Lamingt                                Scholarship
             Commun   on Rd.                                 s
             ity      Branchb                                ($12,500);
             Colleg   urg, NJ                                Galileo
             e        08876                                  Scholars
                                                             Program
                                                             ($5,000);
                                                             Textbook
                                                             Scholarship
                                                             s ($2,500)
------------------------------------------------------------------------
Monetary    Regions  640              $15,000    5/24/2017  Make It OK
             Hospit   Jackson
             al       Street,
             Founda   MS
             tion     11202C
                      St.
                      Paul,
                      MN
                      55101
------------------------------------------------------------------------
Monetary    Rescue   98               $25,000   10/16/2017  Emergency
             Missio   Carroll                                Services
             n of     Street                                 Program
             Trento   P.O.
             n        Box 790
                      Trenton
                      , NJ
                      08605-
                      0790
------------------------------------------------------------------------
Monetary    Rider    2083             $19,500   10/30/2017  Summer STEM
             Univer   Lawrenc                                ($12,000);
             sity     eville                                 Scholarship
                      Rd.                                    Support
                      Lawrenc                                ($5,000);
                      eville,                                Shakespeari
                      NJ                                     an at Rider
                      08648                                  ($2,500)
------------------------------------------------------------------------
Monetary    Riverbe  P.O. Box          $5,000    8/14/2017  InSHAPE
             nd       2032                                   Program
             Commun   Concord
             ity      , NH
             Mental   03302-
             Health   2032
             , Inc.
------------------------------------------------------------------------
Monetary    Riversi  P.O. Box         $10,000    12/4/2017  Riverside
             de       650                                    Symphonia
             Sympho   Lambert                                Senior
             nia,     ville,                                 Outreach
             Inc.     NJ                                     Program
                      08530
------------------------------------------------------------------------
Monetary    Robert   One               $8,500   12/18/2017  Girls to
             Wood     Hamilto                                Women: Myth
             Johnso   n                                      vs. Reality
             n        Health
             Hamilt   Place
             on       Hamilto
             Founda   n, NJ
             tion     08690
------------------------------------------------------------------------
Monetary    Rush     2000              $2,500   10/16/2017  Fox Valley
             Copley   Ogden                                  Heart Fund
             Founda   Ave.
             tion     Aurora,
                      IL
                      60504
------------------------------------------------------------------------
Monetary    Rutgers  7                   $300    9/29/2017  Costs
             Univer   College                                associated
             sity     Avenue                                 with
             Founda   Winants                                Janssen
             tion     Hall                                   Cares
                      New                                    Volunteer
                      Brunswi                                Activity--S
                      ck, NJ                                 eptember
                      08901                                  20, 2017
------------------------------------------------------------------------
Monetary    Rutgers  4                 $8,546   12/18/2017  Corporate
             Univer   Hunting                                Social
             sity     ton                                    Responsibil
             School   Street                                 ity
             of       New                                    Fellowship
             Commun   Brunswi
             icatio   ck, NJ
             n,       08901-1
             Inform   071
             ation
             and
             Librar
             y
             Studie
             s
------------------------------------------------------------------------
Monetary    SAFE in  46 East             $300    9/29/2017  Costs
             Hunter   Main                                   associated
             don      Street                                 with
                      Fleming                                Janssen
                      ton, NJ                                Cares
                      08822                                  Volunteer
                                                             Activity--S
                                                             eptember
                                                             19, 2017
------------------------------------------------------------------------
Monetary    SAFE in  46 East             $300    9/29/2017  Costs
             Hunter   Main                                   associated
             don      Street                                 with
                      Fleming                                Janssen
                      ton, NJ                                Cares
                      08822                                  Volunteer
                                                             Activity--S
                                                             eptember
                                                             18, 2017
------------------------------------------------------------------------
Monetary    San      P.O. Box          $5,000    8/15/2017  Behavioral
             Franci   410836                                 Health
             sco      San                                    Court's
             Genera   Francis                                Motivationa
             l        co, CA                                 l
             Hospit   94110                                  Incentives
             al                                              Program
             Founda
             tion
------------------------------------------------------------------------
Monetary    SAVE A   900                 $300    9/29/2017  Costs
             Friend   Herront                                associated
             to       own                                    with
             Homele   Road                                   Janssen
             ss       Princet                                Cares
             Animal   on NJ                                  Volunteer
             s        08540                                  Activity--S
                                                             eptember
                                                             22, 2017
------------------------------------------------------------------------
Monetary    Schizop  P.O. Box         $15,000   12/12/2017  HVoS
             hrenia   94122                                  (Hearing
             And      Houston                                Voices of
             Relate   , TX                                   Support)
             d        77094                                  Perception
             Disord                                          Changing
             ers                                             Experientia
             Allian                                          l
             ce Of                                           Installatio
             Americ                                          n and
             a                                               Scientific
                                                             Briefing
------------------------------------------------------------------------
Monetary    SERV     20                $5,000   10/16/2017  SERV 15th
             Founda   Scotch                                 Annual
             tion,    Road                                   Wellness
             Inc.     Ewing,                                 and
                      NJ                                     Development
                      08628                                  Conference
------------------------------------------------------------------------
Monetary    SERV     20                $7,500   10/16/2017  SERV
             Founda   Scotch                                 Foundation
             tion,    Road                                   Scholarship
             Inc.     Ewing,                                 Fund
                      NJ
                      08628
------------------------------------------------------------------------
Monetary    SERV     20                  $300    8/24/2017  Costs
             Founda   Scotch                                 associated
             tion,    Road                                   with
             Inc.     Ewing,                                 Janssen
                      NJ                                     Cares
                      08628                                  Volunteer
                                                             Activity--A
                                                             ugust 20,
                                                             2017
------------------------------------------------------------------------
Monetary    Shannon  36                  $500    12/5/2017  Shannon
             Daley    Indian                                 Daley
             Memori   Run                                    Memorial
             al       P.O.                                   Fund
             Fund     Box                                    Charity
                      1271                                   Events
                      Whiteho
                      use
                      Station
                      , NJ
                      08889
------------------------------------------------------------------------
Monetary    The      1920              $2,500    8/14/2017  1920 Club
             Sharin   10th                                   Art Program
             g        Avenue
             Place,   South
             Inc.     P.O.
                      Box
                      59455
                      Birming
                      ham, AL
                      35255
------------------------------------------------------------------------
Monetary    Sisters  1201              $5,000   10/30/2017  Pearl Grace
             Networ   Hamilto                                Memorial
             k of     n                                      Golf
             Centra   Street                                 Tournament
             l New    Somerse
             Jersey   t, NJ
                      08873
------------------------------------------------------------------------
Monetary    Somerse  190 Lord            $300    8/24/2017  Costs
             t        Stirlin                                associated
             County   g Road                                 with
             Park     Basking                                Janssen
             Founda   Ridge,                                 Cares
             tion     NJ                                     Volunteer
                      07920                                  Activity--S
                                                             eptember
                                                             15, 2017
------------------------------------------------------------------------
Monetary    Special  1 Eunice          $7,500   12/12/2017  Special
             Olympi   Kennedy                                Olympics
             cs New   Shriver                                New Jersey--
             Jersey   Way                                    Camp
                      Lawrenc                                Shriver
                      e
                      Townshi
                      p, NJ
                      08648
------------------------------------------------------------------------
Monetary    St.      One              $20,000    12/4/2017  Providing
             Mary     Summit                                 Food for
             Medica   Square,                                Underserved
             l        Suite                                  Children in
             Center   300                                    Bucks
             Founda   1717                                   County: The
             tion     Langhor                                St. Mary
                      ne-                                    Backpacks
                      Newtown                                for Kids
                      Rd.                                    Program
                      Langhor
                      ne, PA
                      19047
------------------------------------------------------------------------
Monetary    Stony    31 Titus         $15,000   12/18/2017  StreamWatch:
             Brook    Mill                                   Citizen
             Millst   Road                                   Scientists
             one      Penning                                Monitoring
             Waters   ton, NJ                                Water
             hed      08534                                  Quality in
             Associ                                          Central New
             ation                                           Jersey
------------------------------------------------------------------------
Monetary    TASK,    72\1/2\          $25,000   10/30/2017  Meal Service
             Inc.     Escher                                 Program
                      Street
                      Trenton
                      , NJ
                      08609
------------------------------------------------------------------------
Monetary    The Arc  180               $5,000   12/18/2017  The Arc
             Mercer   Ewingvi                                Mercer and
                      lle                                    Medina
                      Road                                   Community
                      Ewing,                                 Clinic
                      NJ
                      08683
------------------------------------------------------------------------
Monetary    The      Paul              $5,000   10/27/2017  Communiversi
             Arts     Robeson                                ty ArtsFest
             Counci   Center                                 2018
             l of     for the
             Prince   Arts
             ton      102
                      Withers
                      poon
                      Street
                      Princet
                      on, NJ
                      08542
------------------------------------------------------------------------
Monetary    The      Paul             $10,000   10/27/2017  Arts Council
             Arts     Robeson                                of
             Counci   Center                                 Princeton
             l of     for the                                Community
             Prince   Arts                                   Outreach
             ton      102                                    Programs
                      Withers
                      poon
                      Street
                      Princet
                      on, NJ
                      08542
------------------------------------------------------------------------
Monetary    The      Paul                $300    9/29/2017  Costs
             Arts     Robeson                                associated
             Counci   Center                                 with
             l of     for the                                Janssen
             Prince   Arts                                   Cares
             ton      102                                    Volunteer
                      Withers                                Activity--S
                      poon                                   eptember
                      Street                                 11, 2017
                      Princet
                      on, NJ
                      08542
------------------------------------------------------------------------
Monetary    The      2020              $2,000    11/6/2017  Art Classes
             Center   Burnt                                  for
             for      Mills                                  Children
             Contem   Road                                   with Autism
             porary   Bedmins                                Spectrum
             Art      ter, NJ                                Disorder
                      07882                                  and Other
                                                             Special
                                                             Needs
------------------------------------------------------------------------
Monetary    The      19B                 $300    8/24/2017  Costs
             Center   Dellwoo                                associated
             For      d Lane                                 with
             Great    Somerse                                Janssen
             Expect   t, NJ                                  Cares
             ations   08873                                  Volunteer
                                                             Activity--S
                                                             eptember
                                                             19, 2017
------------------------------------------------------------------------
Monetary    The      19B              $12,000    9/15/2017  Adult
             Center   Dellwoo                                Women's
             For      d Lane                                 Program
             Great    Somerse
             Expect   t, NJ
             ations   08873
------------------------------------------------------------------------
Monetary    The      205               $7,500   10/30/2017  The Edinburg
             Edinbu   Burling                                Center Jail
             rg       ton                                    Diversion
             Center   Road                                   Program
                      Lexingt
                      on, MA
                      01730
------------------------------------------------------------------------
Monetary    The      401               $1,000     5/4/2017  8th Annual
             Mental   Cypress                                Run/Walk
             Health   Street                                 for Mental
             Center   Manches                                Health
             Of       ter, NH
             Greate   03103
             r
             Manche
             ster
------------------------------------------------------------------------
Monetary    The      400                 $300    9/29/2017  Costs
             Pennsb   Pennsbu                                associated
             ury      ry                                     with
             Societ   Memoria                                Janssen
             y        l Rd.                                  Cares
                      Morrisv                                Volunteer
                      ille,                                  Activity--S
                      PA                                     eptember
                      19067                                  25, 2017
------------------------------------------------------------------------
Monetary    The      P.O. Box          $9,000    12/5/2017  Opera for
             Prince   2063                                   All
             ton      Princet
             Festiv   on, NJ
             al       08543
------------------------------------------------------------------------
Monetary    The      243               $5,000   12/14/2017  Sensory
             Roxey    North                                  Friendly
             Ballet   Union                                  Performance
             Compan   Street                                 s at
             y,       Lambert                                Trenton
             Inc.     ville,                                 Psychiatric
                      NJ                                     Hospital
                      08530                                  and The
                                                             College of
                                                             New Jersey
------------------------------------------------------------------------
Monetary    The      4101             $20,000    9/26/2017  MindStrong
             Thresh   North
             olds     Ravensw
                      ood
                      Avenue
                      Chicago
                      , IL
                      60613
------------------------------------------------------------------------
Monetary    The      100              $10,000    8/30/2017  Farm Based
             Willia   Gould                                  Psychiatric
             m J.     Road                                   Rehabilitat
             Gould    P.O.                                   ion and
             Associ   Box 157                                Recovery
             ates,    Montere
             Inc.     y, MA
                      01245
------------------------------------------------------------------------
Monetary    Thomas   111 West         $15,000   12/18/2017  Scholarships
             Edison   State                                  for Nursing
             State    Street                                 Students
             Colleg   Trenton                                Enrolled in
             e        , NJ                                   the
             Founda   08608                                  Accelerated
             tion                                            Second
                                                             Degree BSN
                                                             Program at
                                                             the W. Cary
                                                             Edwards
                                                             School of
                                                             Nursing at
                                                             Thomas
                                                             Edison
                                                             State
                                                             University.
------------------------------------------------------------------------
Monetary    TPTO     51 South          $1,500   10/30/2017  2018
             Inc--T   Timberl                                Timberlane
             imberl   ane                                    Science and
             ane      Drive                                  Engineering
             Parent   Penning                                Fair
             Teache   ton, NJ
             r        08534
             Organi
             zation
------------------------------------------------------------------------
Monetary    Trenton  471               $7,500   12/18/2017  Trenton
             Childr   Parkway                                Children's
             en's     Avenue                                 Chorus
             Chorus   Trenton
             , Inc.   , NJ
                      08618
------------------------------------------------------------------------
Monetary    Trenton  P.O. Box          $8,500    11/6/2017  Second
             Commun   5206                                   Semester
             ity      Trenton                                Programs,
             Music    , NJ                                   Trenton
             School   08638                                  Music
                                                             Makers
------------------------------------------------------------------------
Monetary    Trenton  635               $5,000    12/4/2017  Trenton
             Educat   South                                  Education
             ion      Clinton                                Dance
             Dance    Avenue                                 Institute
             Instit   Trenton                                (TEDI)
             ute      , NJ
                      08611
------------------------------------------------------------------------
Monetary    Trenton  218              $19,000   10/27/2017  Wheels to
             Health   North                                  Wellness
             Team     Broad
             Inc.     Street
                      Trenton
                      , NJ
                      08608
------------------------------------------------------------------------
Monetary    Trinity  22                $7,500   10/30/2017  TCS General
             Counse   Stockto                                Counseling
             ling     n                                      and
             Servic   Street                                 Prevention
             es       Princet                                Programming
                      on, NJ
                      08540
------------------------------------------------------------------------
Monetary    Tuscalo  P.O. Box          $1,000     5/4/2017  Hot Hundred
             osa      2322                                   2017
             Mental   Tuscalo
             Health   osa, AL
             Allian   35403
             ce
------------------------------------------------------------------------
Monetary    Twiligh  P.O. Box          $7,500   10/30/2017  Simple Needs
             t Wish   1042                                   Wish
             Founda   Doylest                                Granting
             tion     own, PA                                Program
                      18901
------------------------------------------------------------------------
Monetary    UIH      4 North          $10,000   12/18/2017  Healthy
             Family   Broad                                  Relationshi
             Partne   Street                                 ps, Healthy
             rs       Suite                                  Choices
                      2R
                      Trenton
                      , NJ
                      08608
------------------------------------------------------------------------
Monetary    UIH      4 North          $20,000   12/18/2017  Community of
             Family   Broad                                  Health for
             Partne   Street                                 Men, Year 4
             rs       Suite
                      2R
                      Trenton
                      , NJ
                      08608
------------------------------------------------------------------------
Monetary    United   60 Park           $7,500   10/30/2017  UNCF
             Negro    Place                                  Scholarship
             Colleg   Suite
             e Fund   406
                      Newark,
                      NJ
                      07102
------------------------------------------------------------------------
Monetary    United   413 Hood         $85,000    9/29/2017  Fresh
             Way of   Blvd                                   Connect
             Bucks    Fairles                                program
             County   s
                      Hills,
                      PA
                      19030
------------------------------------------------------------------------
Monetary    United   413 Hood         $42,500    9/29/2017  Emergency
             Way of   Blvd                                   Needs
             Bucks    Fairles                                program
             County   s
                      Hills,
                      PA
                      19030
------------------------------------------------------------------------
Monetary    United   3150             $85,000   10/30/2017  United Way
             Way of   Brunswi                                of Greater
             Greate   ck Pike                                Mercer
             r        Suite                                  County
             Mercer   230                                    Minority
             County   Lawrenc                                and
                      eville,                                Multicultur
                      NJ                                     al Health
                      08648                                  Initiative
------------------------------------------------------------------------
Monetary    United   3150                $920    12/4/2017  Costs
             Way of   Brunswi                                associated
             Greate   ck Pike                                with
             r        Suite                                  Janssen
             Mercer   230                                    Cares
             County   Lawrenc                                Volunteer
                      eville,                                Activity--S
                      NJ                                     eptember
                      08648                                  26, 2017
------------------------------------------------------------------------
Monetary    UrbanPr  801 West          $2,770   12/12/2017  Mindfulness
             omise    State                                  Pilot
             Intern   Street                                 Program
             ationa   Trenton
             l,       , NJ
             Inc.     08618
------------------------------------------------------------------------
Monetary    Valeo    5401 SW           $3,500    9/19/2017  Vocational
             Behavi   7th                                    Empowerment
             oral     Street                                 Photovoice
             Health   Topeka,
             Care,    KS
             Inc.     66606
------------------------------------------------------------------------
Monetary    Visions  49                $7,500   12/12/2017  Street-Smart
             and      Brahma                                 HIV/AIDS
             Pathwa   Ave.
             ys       Bridgew
                      ater,
                      NJ
                      08807
------------------------------------------------------------------------
Monetary    Visions  49                  $300    11/6/2017  Costs
             and      Brahma                                 associated
             Pathwa   Ave.                                   with
             ys       Bridgew                                Janssen
                      ater,                                  Cares
                      NJ                                     Volunteer
                      08807                                  Activity
------------------------------------------------------------------------
Monetary    Volunte  12                $9,000    12/1/2017  SkillsConnec
             er       Stockto                                t
             Connec   n
             t        Street
                      Princet
                      on, NJ
                      08540
------------------------------------------------------------------------
Monetary    Washing  P.O. Box            $750   10/16/2017  Revolutionar
             ton      83                                     y War
             Crossi   Titusvi                                Weekend
             ng       lle, NJ
             Park     08560
             Associ
             ation,
             Inc.
------------------------------------------------------------------------
Monetary    We Care  3035              $1,500    5/31/2017  ArtWORK
             Arts     Wilming
                      ton
                      Pike
                      Ketteri
                      ng, OH
                      45429
------------------------------------------------------------------------
Monetary    West     P.O. Box          $5,000    12/5/2017  Excellence
             Windso   280                                    in
             r        West                                   Education,
             Plains   Windsor                                and
             boro     , NJ                                   Innovation
             Educat   08550                                  Fair 2018
             ion
             Founda
             tion
------------------------------------------------------------------------
Monetary    Westmor  100                  $75    3/22/2017  Employee
             eland    Devonsh                                directed
             County   ire                                    donation in
             Food     Drive                                  lieu of
             Bank,    Delmont                                company
             Inc.     , PA                                   holiday
                      15626-                                 gift
                      1607
------------------------------------------------------------------------
Monetary    Womansp  1530              $7,500    12/5/2017  Safe House
             ace      Brunswi                                (Emergency
                      ck Ave.                                Shelter)
                      Lawrenc                                and
                      eville,                                Barbara's
                      NJ                                     House
                      08648                                  (Transition
                                                             al
                                                             Housing):
                                                             Supporting
                                                             Women and
                                                             Children
                                                             Impacted by
                                                             Domestic
                                                             Violence
------------------------------------------------------------------------
Monetary    Womansp  1530                $300    9/29/2017  Costs
             ace      Brunswi                                associated
                      ck Ave.                                with
                      Lawrenc                                Janssen
                      eville,                                Cares
                      NJ                                     Volunteer
                      08648                                  Activity--O
                                                             ctober 2,
                                                             2017
------------------------------------------------------------------------
Monetary    Womansp  1530                $300    9/29/2017  Costs
             ace      Brunswi                                associated
                      ck Ave.                                with
                      Lawrenc                                Janssen
                      eville,                                Cares
                      NJ                                     Volunteer
                      08648                                  Activity--O
                                                             ctober 5,
                                                             2017
------------------------------------------------------------------------
Monetary    Woods    40                $4,000   12/12/2017  Yoga at
             Servic   Martin                                 Woods
             es       Gross                                  Services: A
             Founda   Drive,                                 Recreationa
             tion     P.O.                                   l Program
                      Box 36                                 for People
                      Langhor                                with
                      ne, PA                                 Special
                      19047                                  Needs
------------------------------------------------------------------------
Monetary    Young    349 W.            $3,500   12/18/2017  Early
             Schola   State                                  Literacy
             rs'      St                                     Engagement
             Instit   Trenton                                and
             ute      , NJ                                   Development
                      08618
------------------------------------------------------------------------
Product     AmeriCa  88              $493,168     1/3/2017  Product
             res      Hamilto                                donation
             Founda   n Ave.                                 for
             tion     Stamfor                                humanitaria
                      d, CT                                  n
                      06902                                  assistance
                                                             in
                                                             Dominican
                                                             Republic,
                                                             Nicaragua,
                                                             West Bank,
                                                             and U.S.
------------------------------------------------------------------------
Product     AmeriCa  88              $145,709     1/6/2017  Product
             res      Hamilto                                donation
             Founda   n Ave.                                 for
             tion     Stamfor                                humanitaria
                      d, CT                                  n
                      06902                                  assistance
                                                             in
                                                             Nicaragua,
                                                             Dominican
                                                             Republic,
                                                             West Bank,
                                                             and U.S.
------------------------------------------------------------------------
Product     AmeriCa  88              $257,792     1/9/2017  Product
             res      Hamilto                                donation
             Founda   n Ave.                                 for
             tion     Stamfor                                humanitaria
                      d, CT                                  n
                      06902                                  assistance
                                                             in
                                                             Nicaragua,
                                                             Dominican
                                                             Republic,
                                                             West Bank,
                                                             and U.S.
------------------------------------------------------------------------
Product     AmeriCa  88              $100,065    2/16/2017  Product
             res      Hamilto                                donation
             Founda   n Ave.                                 for
             tion     Stamfor                                humanitaria
                      d, CT                                  n
                      06902                                  assistance
                                                             in St.
                                                             Lucia,
                                                             Nicaragua,
                                                             Republic,
                                                             and Lebanon
------------------------------------------------------------------------
Product     AmeriCa  88            $1,185,644    2/16/2017  Product
             res      Hamilto                                donation
             Founda   n Ave.                                 for
             tion     Stamfor                                humanitaria
                      d, CT                                  n
                      06902                                  assistance
                                                             in U.S.
                                                             clinics
------------------------------------------------------------------------
Product     AmeriCa  88                $4,640    3/13/2017  Product
             res      Hamilto                                donation
             Founda   n Ave.                                 for
             tion     Stamfor                                humanitaria
                      d, CT                                  n
                      06902                                  assistance
                                                             in Puerto
                                                             Rico
------------------------------------------------------------------------
Product     AmeriCa  88            $1,281,296    3/20/2017  Product
             res      Hamilto                                donation
             Founda   n Ave.                                 for
             tion     Stamfor                                humanitaria
                      d, CT                                  n
                      06902                                  assistance
                                                             in
                                                             Tanzania,
                                                             West Bank,
                                                             Gaza, St.
                                                             Lucia,
                                                             Lebanon,
                                                             Dominican
                                                             Republic,
                                                             Colombia,
                                                             Nicaragua,
                                                             and U.S.
------------------------------------------------------------------------
Product     AmeriCa  88               $91,239    3/20/2017  Product
             res      Hamilto                                donation
             Founda   n Ave.                                 for
             tion     Stamfor                                humanitaria
                      d, CT                                  n
                      06902                                  assistance
                                                             in
                                                             Nicaragua
                                                             and
                                                             Colombia
------------------------------------------------------------------------
Product     AmeriCa  88            $1,077,988    4/11/2017  Product
             res      Hamilto                                donation
             Founda   n Ave.                                 for
             tion     Stamfor                                humanitaria
                      d, CT                                  n
                      06902                                  assistance
                                                             in Gaza,
                                                             West Bank,
                                                             Colombia,
                                                             and U.S.
------------------------------------------------------------------------
Product     AmeriCa  88              $181,140    4/11/2017  Product
             res      Hamilto                                donation
             Founda   n Ave.                                 for
             tion     Stamfor                                humanitaria
                      d, CT                                  n
                      06902                                  assistance
                                                             in St.
                                                             Lucia,
                                                             Afghanistan
                                                             , and
                                                             Colombia
------------------------------------------------------------------------
Product     AmeriCa  88              $191,031    5/23/2017  Product
             res      Hamilto                                donation
             Founda   n Ave.                                 for
             tion     Stamfor                                humanitaria
                      d, CT                                  n
                      06902                                  assistance
                                                             in
                                                             Nicaragua,
                                                             Dominican
                                                             Republic,
                                                             and St.
                                                             Lucia
------------------------------------------------------------------------
Product     AmeriCa  88               $72,844    5/23/2017  Product
             res      Hamilto                                donation
             Founda   n Ave.                                 for
             tion     Stamfor                                humanitaria
                      d, CT                                  n
                      06902                                  assistance
                                                             in
                                                             Nicaragua.
------------------------------------------------------------------------
Product     AmeriCa  88              $871,110    6/22/2017  Product
             res      Hamilto                                donation
             Founda   n Ave.                                 for
             tion     Stamfor                                humanitaria
                      d, CT                                  n
                      06902                                  assistance
                                                             in
                                                             Dominican
                                                             Republic,
                                                             St. Lucia,
                                                             and West
                                                             Bank
------------------------------------------------------------------------
Product     AmeriCa  88              $185,347    6/22/2017  Product
             res      Hamilto                                donation
             Founda   n Ave.                                 for
             tion     Stamfor                                humanitaria
                      d, CT                                  n
                      06902                                  assistance
                                                             in
                                                             Dominican
                                                             Republic,
                                                             and West
                                                             Bank
------------------------------------------------------------------------
Product     AmeriCa  88            $9,583,716    7/17/2017  Product
             res      Hamilto                                donation
             Founda   n Ave.                                 for
             tion     Stamfor                                humanitaria
                      d, CT                                  n
                      06902                                  assistance
                                                             in
                                                             Kyrgyzstan
------------------------------------------------------------------------
Product     AmeriCa  88              $149,758    7/19/2017  Product
             res      Hamilto                                donation
             Founda   n Ave.                                 for
             tion     Stamfor                                humanitaria
                      d, CT                                  n
                      06902                                  assistance
                                                             in St.
                                                             Lucia
------------------------------------------------------------------------
Product     AmeriCa  88               $91,601    8/21/2017  Product
             res      Hamilto                                donation
             Founda   n Ave.                                 for
             tion     Stamfor                                humanitaria
                      d, CT                                  n
                      06902                                  assistance
                                                             in United
                                                             States
------------------------------------------------------------------------
Product     AmeriCa  88              $259,213    8/21/2017  Product
             res      Hamilto                                donation
             Founda   n Ave.                                 for
             tion     Stamfor                                humanitaria
                      d, CT                                  n
                      06902                                  assistance
                                                             in United
                                                             States
------------------------------------------------------------------------
Product     AmeriCa  88              $383,085    9/27/2017  Pharmaceutic
             res      Hamilto                                al product
             Founda   n Ave.                                 Donation
             tion     Stamfor                                for
                      d, CT                                  humanitaria
                      06902                                  n aid in
                                                             Gaza, St.
                                                             Lucia, and
                                                             Peru
------------------------------------------------------------------------
Product     AmeriCa  88              $134,651    9/27/2017  Product
             res      Hamilto                                donation
             Founda   n Ave.                                 for
             tion     Stamfor                                humanitaria
                      d, CT                                  n aid for
                      06902                                  El
                                                             Salvador,
                                                             Peru and
                                                             St. Lucia
------------------------------------------------------------------------
Product     AmeriCa  88            $2,013,098   10/10/2017  Product for
             res      Hamilto                                humanitaria
             Founda   n Ave.                                 n and
             tion     Stamfor                                disaster
                      d, CT                                  response in
                      06902                                  Houston,
                                                             Florida and
                                                             Puerto Rico
------------------------------------------------------------------------
Product     AmeriCa  88               $65,375   10/10/2017  Product
             res      Hamilto                                donation
             Founda   n Ave.                                 for
             tion     Stamfor                                humanitaria
                      d, CT                                  n and
                      06902                                  disaster
                                                             relief in
                                                             Houston,
                                                             Florida,
                                                             and Puerto
                                                             Rico
------------------------------------------------------------------------
Product     AmeriCa  88               $75,473   10/20/2017  Product
             res      Hamilto                                donation
             Founda   n Ave.                                 for
             tion     Stamfor                                humanitaria
                      d, CT                                  n aid in
                      06902                                  Nicaragua
                                                             and US
                                                             Clinics
------------------------------------------------------------------------
Product     AmeriCa  88               $82,469   11/15/2017  Product
             res      Hamilto                                donation
             Founda   n Ave.                                 for
             tion     Stamfor                                humanitaria
                      d, CT                                  n aid in US
                      06902                                  Clinic
                                                             Network
------------------------------------------------------------------------
Product     AmeriCa  88              $442,409   11/15/2017  Product
             res      Hamilto                                donation
             Founda   n Ave.                                 for
             tion     Stamfor                                humanitaria
                      d, CT                                  n aid in
                      06902                                  Sierra
                                                             Leone
------------------------------------------------------------------------
Product     AmeriCa  88              $816,348    8/31/2017  Product
             res      Hamilto                                Donation
             Founda   n Ave.                                 for
             tion     Stamfor                                Disaster
                      d, CT                                  Response--H
                      06902                                  urricane
                                                             Harvey
------------------------------------------------------------------------
Product     AmeriCa  88            $1,320,624   11/17/2017  Product
             res      Hamilto                                donation
             Founda   n Ave.                                 for
             tion     Stamfor                                humanitaria
                      d, CT                                  n
                      06902                                  assistance
                                                             in U.S
------------------------------------------------------------------------
Product     AmeriCa  88              $504,595    12/5/2017  Product
             res      Hamilto                                donation
             Founda   n Ave.                                 for
             tion     Stamfor                                humanitaria
                      d, CT                                  n
                      06902                                  assistance
                                                             in the
                                                             Dominican
                                                             Republic
------------------------------------------------------------------------
Product     AmeriCa  88              $971,862    12/5/2017  Product for
             res      Hamilto                                humanitaria
             Founda   n Ave.                                 n
             tion     Stamfor                                assistance
                      d, CT                                  in the
                      06902                                  Dominican
                                                             Republic
------------------------------------------------------------------------
Product     AmeriCa  88            $4,298,976    12/5/2017  Product
             res      Hamilto                                donation
             Founda   n Ave.                                 for
             tion     Stamfor                                humanitaria
                      d, CT                                  n
                      06902                                  assistance
                                                             in US
                                                             Clinic
                                                             Networks
------------------------------------------------------------------------
Product     Catholi  100 Wall        $432,510   11/16/2017  Product
             c        Street,                                donation
             Medica   9th                                    for
             l        Floor                                  humanitaria
             Missio   New                                    n
             n        York,                                  assistance
             Board    NY                                     in:
                      10005                                  Dominican
                                                             Republic,
                                                             Haiti and
                                                             Guatemala
------------------------------------------------------------------------
Product     Catholi  100 Wall        $566,919   11/16/2017  Product
             c        Street,                                donation
             Medica   9th                                    for
             l        Floor                                  humanitaria
             Missio   New                                    n
             n        York,                                  assistance
             Board    NY                                     in:
                      10005                                  Dominican
                                                             Republic,
                                                             Haiti, and
                                                             Guatemala
------------------------------------------------------------------------
Product     Catholi  100 Wall         $68,662   10/20/2017  Product
             c        Street,                                donation
             Medica   9th                                    for
             l        Floor                                  humanitaria
             Missio   New                                    n
             n        York,                                  assistance
             Board    NY                                     in the
                      10005                                  Dominican
                                                             Republic,
                                                             Guatemala
                                                             and Haiti
------------------------------------------------------------------------
Product     Catholi  100 Wall         $47,020    9/27/2017  Product
             c        Street,                                donation
             Medica   9th                                    for
             l        Floor                                  humanitaria
             Missio   New                                    n aid in
             n        York,                                  the
             Board    NY                                     Dominican
                      10005                                  Republic
------------------------------------------------------------------------
Product     Catholi  33-01         $1,626,679    7/19/2017  Product
             c        Elevent                                donation
             Medica   h                                      for
             l        Street                                 humanitaria
             Missio   Long                                   n
             n        Island                                 assistance
             Board    City,                                  in
                      NY                                     Guatemala,
                                                             Haiti,
                                                             Dominican
                                                             Republic,
                                                             and
                                                             Nicaragua
------------------------------------------------------------------------
Product     Catholi  33-01         $2,839,769    7/19/2017  Product
             c        Elevent                                donation
             Medica   h                                      for
             l        Street                                 humanitaria
             Missio   Long                                   n
             n        Island                                 assistance
             Board    City,                                  in
                      NY                                     Guatemala,
                                                             Haiti,
                                                             Dominican
                                                             Republic,
                                                             and
                                                             Nicaragua
------------------------------------------------------------------------
Product     Catholi  100 Wall        $129,896    8/21/2017  Product
             c        Street,                                donation
             Medica   9th                                    for
             l        Floor                                  humanitaria
             Missio   New                                    n
             n        York,                                  assistance
             Board    NY                                     in
                      10005                                  Dominican
                                                             Republic,
                                                             and
                                                             Nicaragua
------------------------------------------------------------------------
Product     Catholi  100 Wall      $2,091,213    8/21/2017  Product
             c        Street,                                donation
             Medica   9th                                    for
             l        Floor                                  humanitaria
             Missio   New                                    n
             n        York,                                  assistance
             Board    NY                                     in
                      10005                                  Dominican
                                                             Republic,
                                                             Haiti, and
                                                             Nicaragua
------------------------------------------------------------------------
Product     Catholi  33-01           $698,911    6/22/2017  Product
             c        Elevent                                donation
             Medica   h                                      for
             l        Street                                 humanitaria
             Missio   Long                                   n
             n        Island                                 assistance
             Board    City,                                  in
                      NY                                     Guatemala,
                                                             El
                                                             Salvador,
                                                             Nicaragua,
                                                             Haiti, and
                                                             Jamaica
------------------------------------------------------------------------
Product     Catholi  33-01           $537,473    6/22/2017  Product
             c        Elevent                                donation
             Medica   h                                      for
             l        Street                                 humanitaria
             Missio   Long                                   n
             n        Island                                 assistance
             Board    City,                                  in
                      NY                                     Dominican
                                                             Republic,
                                                             Haiti,
                                                             Guatemala,
                                                             Jamaica,
                                                             and El
                                                             Salvador
------------------------------------------------------------------------
Product     Catholi  33-01           $597,003    4/10/2017  Product
             c        Elevent                                donation
             Medica   h                                      for
             l        Street                                 humanitaria
             Missio   Long                                   n
             n        Island                                 assistance
             Board    City,                                  in El
                      NY                                     Salvador,
                                                             Haiti, and
                                                             Nicaragua
------------------------------------------------------------------------
Product     Catholi  33-01           $565,051    4/10/2017  Product
             c        Elevent                                donation
             Medica   h                                      for
             l        Street                                 humanitaria
             Missio   Long                                   n
             n        Island                                 assistance
             Board    City,                                  in El
                      NY                                     Salvador,
                                                             Haiti,
                                                             Honduras,
                                                             Nicaragua,
                                                             and
                                                             Guatemala
------------------------------------------------------------------------
Product     Catholi  33-01           $610,715    5/23/2017  Product
             c        Elevent                                donation
             Medica   h                                      for
             l        Street                                 humanitaria
             Missio   Long                                   n
             n        Island                                 assistance
             Board    City,                                  in
                      NY                                     Tanzania,
                                                             Guatemala,
                                                             Jamaica,
                                                             and
                                                             Dominican
                                                             Republic
------------------------------------------------------------------------
Product     Catholi  33-01           $716,298    5/23/2017  Product
             c        Elevent                                donation
             Medica   h                                      for
             l        Street                                 humanitaria
             Missio   Long                                   n
             n        Island                                 assistance
             Board    City,                                  in
                      NY                                     Dominican
                                                             Republic,
                                                             Tanzania,
                                                             and
                                                             Guatemala
------------------------------------------------------------------------
Product     Catholi  33-01         $1,336,614    3/20/2017  Product
             c        Elevent                                donation
             Medica   h                                      for
             l        Street                                 humanitaria
             Missio   Long                                   n
             n        Island                                 assistance
             Board    City,                                  in
                      NY                                     Guatemala,
                                                             El
                                                             Salvador,
                                                             and Haiti
------------------------------------------------------------------------
Product     Catholi  33-01           $102,932    3/20/2017  Product
             c        Elevent                                donation
             Medica   h                                      for
             l        Street                                 humanitaria
             Missio   Long                                   n
             n        Island                                 assistance
             Board    City,                                  in
                      NY                                     Guatemala
                                                             and Haiti
------------------------------------------------------------------------
Product     Catholi  33-01           $117,953    2/15/2017  Product
             c        Elevent                                donation
             Medica   h                                      for
             l        Street                                 humanitaria
             Missio   Long                                   n
             n        Island                                 assistance
             Board    City,                                  in Haiti,
                      NY                                     El Salvador
                                                             and
                                                             Honduras
------------------------------------------------------------------------
Product     Direct   27 S. La      $1,051,504    3/20/2017  Product
             Relief   Patera                                 donation
                      Lane                                   for
                      Santa                                  humanitaria
                      Barbara                                n
                      , CA                                   assistance
                      93117                                  in
                                                             Honduras,
                                                             Liberia,
                                                             Haiti and
                                                             El
                                                             Salvador.
------------------------------------------------------------------------
Product     Direct   27 S. La         $91,239    3/20/2017  Product
             Relief   Patera                                 donation
                      Lane                                   for
                      Santa                                  humanitaria
                      Barbara                                n
                      , CA                                   assistance
                      93117                                  in Haiti
                                                             and
                                                             Liberia.
------------------------------------------------------------------------
Product     Direct   27 S. La         $23,107    2/16/2017  Product
             Relief   Patera                                 donation
                      Lane                                   for
                      Santa                                  humanitaria
                      Barbara                                n
                      , CA                                   assistance
                      93117                                  in
                                                             Honduras.
------------------------------------------------------------------------
Product     Direct   27 S. La        $378,636    2/16/2017  Product
             Relief   Patera                                 donation
                      Lane                                   for
                      Santa                                  humanitaria
                      Barbara                                n
                      , CA                                   assistance
                      93117                                  in
                                                             Honduras.
------------------------------------------------------------------------
Product     Direct   27 S. La      $2,390,729    4/11/2017  Product
             Relief   Patera                                 donation
                      Lane                                   for
                      Santa                                  humanitaria
                      Barbara                                n
                      , CA                                   assistance
                      93117                                  in
                                                             Colombia,
                                                             Sierra
                                                             Leone,
                                                             Vanuatu,
                                                             Ghana,
                                                             Malawi,
                                                             Haiti,
                                                             Nicaragua
                                                             and U.S.
------------------------------------------------------------------------
Product     Direct   27 S. La        $249,548    4/11/2017  Product
             Relief   Patera                                 donation
                      Lane                                   for
                      Santa                                  humanitaria
                      Barbara                                n
                      , CA                                   assistance
                      93117                                  in Ghana,
                                                             Malawi,
                                                             Sierra
                                                             Leone,
                                                             Liberia,
                                                             Pakistan
                                                             and U.S.
------------------------------------------------------------------------
Product     Direct   27 S. La        $804,308    5/23/2017  Product
             Relief   Patera                                 donation
                      Lane                                   for
                      Santa                                  humanitaria
                      Barbara                                n
                      , CA                                   assistance
                      93117                                  in Malawi
                                                             and Sierra
                                                             Leone
------------------------------------------------------------------------
Product     Direct   27 S. La        $209,508    5/23/2017  Product
             Relief   Patera                                 donation
                      Lane                                   for
                      Santa                                  humanitaria
                      Barbara                                n
                      , CA                                   assistance
                      93117                                  in
                                                             Colombia,
                                                             Pakistan,
                                                             Ghana,
                                                             Malawi,
                                                             Sierra
                                                             Leone and
                                                             Liberia.
------------------------------------------------------------------------
Product     Direct   27 S. La        $500,169    6/22/2017  Product
             Relief   Patera                                 donation
                      Lane                                   for
                      Santa                                  humanitaria
                      Barbara                                n
                      , CA                                   assistance
                      93117                                  in Jamaica,
                                                             Nicaragua,
                                                             Pakistan,
                                                             and Liberia
------------------------------------------------------------------------
Product     Direct   27 S. La        $710,949    6/22/2017  Product
             Relief   Patera                                 donation
                      Lane                                   for
                      Santa                                  humanitaria
                      Barbara                                n
                      , CA                                   assistance
                      93117                                  in Jamaica
------------------------------------------------------------------------
Product     Direct   27 S. La      $1,405,277    7/19/2017  Product
             Relief   Patera                                 donation
                      Lane                                   for
                      Santa                                  humanitaria
                      Barbara                                n
                      , CA                                   assistance
                      93117                                  in
                                                             Honduras,
                                                             Colombia,
                                                             and
                                                             Pakistan
------------------------------------------------------------------------
Product     Direct   27 S. La      $1,152,189    7/19/2017  Product
             Relief   Patera                                 Donation
                      Lane                                   for
                      Santa                                  humanitaria
                      Barbara                                n
                      , CA                                   assistance
                      93117                                  in
                                                             Honduras,
                                                             Colombia,
                                                             Pakistan,
                                                             and USA.
------------------------------------------------------------------------
Product     Direct   27 S. La        $271,063    9/27/2017  Product
             Relief   Patera                                 donation
                      Lane                                   for
                      Santa                                  humanitaria
                      Barbara                                n
                      , CA                                   assistance
                      93117                                  in Ghana
------------------------------------------------------------------------
Product     Direct   27 S. La         $61,205    9/27/2017  Product
             Relief   Patera                                 donation
                      Lane                                   for
                      Santa                                  humanitaria
                      Barbara                                n
                      , CA                                   assistance
                      93117                                  in Ghana
------------------------------------------------------------------------
Product     Direct   27 S. La        $373,326    8/21/2017  Product
             Relief   Patera                                 donation
                      Lane                                   for
                      Santa                                  Humanitaria
                      Barbara                                n
                      , CA                                   assistance
                      93117                                  in the
                                                             United
                                                             States
------------------------------------------------------------------------
Product     Direct   27 S. La        $259,561    8/21/2017  Product
             Relief   Patera                                 donation
                      Lane                                   for
                      Santa                                  Humanitaria
                      Barbara                                n
                      , CA                                   assistance
                      93117                                  in the
                                                             United
                                                             States
------------------------------------------------------------------------
Product     Direct   27 S. La        $239,304   10/23/2017  Product
             Relief   Patera                                 donation
                      Lane                                   for
                      Santa                                  humanitaria
                      Barbara                                n
                      , CA                                   assistance
                      93117                                  in US
                                                             Clinics
------------------------------------------------------------------------
Product     Direct   27 S. La        $571,784    12/5/2017  Product
             Relief   Patera                                 donation
                      Lane                                   for
                      Santa                                  humanitaria
                      Barbara                                n
                      , CA                                   assistance
                      93117                                  in Syria
------------------------------------------------------------------------
Product     Direct   27 S. La         $62,628    10/2/2017  Product
             Relief   Patera                                 donation
                      Lane                                   for
                      Santa                                  humanitaria
                      Barbara                                n
                      , CA                                   assistance
                      93117                                  in Houston,
                                                             Florida,
                                                             and Puerto
                                                             Rico
------------------------------------------------------------------------
Product     Direct   27 S. La      $3,961,872   11/17/2017  Product
             Relief   Patera                                 donation
                      Lane                                   for
                      Santa                                  humanitaria
                      Barbara                                n
                      , CA                                   assistance
                      93117                                  in Syria
------------------------------------------------------------------------
Product     Direct   27 S. La      $3,482,171    12/1/2017  Product
             Relief   Patera                                 donation
                      Lane                                   for
                      Santa                                  humanitaria
                      Barbara                                n
                      , CA                                   assistance
                      93117                                  in Syria
------------------------------------------------------------------------
Product     Direct   27 S. La         $82,127     9/7/2017  Product
             Relief   Patera                                 Donation
                      Lane                                   for
                      Santa                                  Disaster
                      Barbara                                response--H
                      , CA                                   urricane
                      93117                                  Harvey
------------------------------------------------------------------------
Product     Direct   27 S. La        $494,813   11/16/2017  Product
             Relief   Patera                                 donation
                      Lane                                   for
                      Santa                                  humanitaria
                      Barbara                                n
                      , CA                                   assistance
                      93117                                  in Syria
------------------------------------------------------------------------
Product     Direct   27 S. La        $224,506   11/16/2017  Product
             Relief   Patera                                 donation
                      Lane                                   for
                      Santa                                  humanitaria
                      Barbara                                n
                      , CA                                   assistance
                      93117                                  in Syria
------------------------------------------------------------------------
Product     Direct   27 S. La        $161,977   11/16/2017  Product
             Relief   Patera                                 donation
                      Lane                                   for
                      Santa                                  humanitaria
                      Barbara                                n
                      , CA                                   assistance
                      93117                                  in Syria
------------------------------------------------------------------------
Product     Direct   27 S. La         $31,448   11/16/2017  Product
             Relief   Patera                                 donation
                      Lane                                   for
                      Santa                                  humanitaria
                      Barbara                                n
                      , CA                                   assistance
                      93117                                  in US
------------------------------------------------------------------------
Product     Direct   27 S. La        $505,634   11/16/2017  Product
             Relief   Patera                                 donation
                      Lane                                   for
                      Santa                                  humanitaria
                      Barbara                                n
                      , CA                                   assistance
                      93117                                  in US
                                                             Clinics
------------------------------------------------------------------------
Product     Heart    1021             $61,205    9/27/2017  Product
             to       Pacific                                donation
             Heart    Avenue                                 for
             Intern   Kansas                                 humanitaria
             ationa   City,                                  n
             l        KS                                     assistance
                      66102                                  in the
                                                             Dominican
                                                             Republic
------------------------------------------------------------------------
Product     Heart    1021            $224,044    9/27/2017  Product
             to       Pacific                                donation
             Heart    Avenue                                 for
             Intern   Kansas                                 humanitaria
             ationa   City,                                  n
             l        KS                                     assistance
                      66102                                  in the
                                                             Dominican
                                                             Republic
------------------------------------------------------------------------
Product     Heart    1021            $979,095    6/22/2017  Product
             to       Pacific                                donation
             Heart    Avenue                                 for
             Intern   Kansas                                 humanitaria
             ationa   City,                                  n
             l        KS                                     assistance
                      66102                                  in
                                                             Honduras.
------------------------------------------------------------------------
Product     Heart    1021            $126,867    6/22/2017  Product
             to       Pacific                                Donation
             Heart    Avenue                                 for
             Intern   Kansas                                 humanitaria
             ationa   City,                                  n
             l        KS                                     assistance
                      66102                                  in
                                                             Honduras.
------------------------------------------------------------------------
Product     Heart    1021            $436,536    4/10/2017  Product
             to       Pacific                                donation
             Heart    Avenue                                 for
             Intern   Kansas                                 humanitaria
             ationa   City,                                  n
             l        KS                                     assistance
                      66102                                  in
                                                             Dominican
                                                             Republic,
                                                             Honduras
                                                             and Papua
                                                             New Guinea.
------------------------------------------------------------------------
Product     Heart    1021             $62,476    4/10/2017  Product
             to       Pacific                                donation
             Heart    Avenue                                 for
             Intern   Kansas                                 humanitaria
             ationa   City,                                  n
             l        KS                                     assistance
                      66102                                  in Honduras
                                                             and
                                                             Dominican
                                                             Republic.
------------------------------------------------------------------------
Product     Johnson  One         $338,315,809   12/31/2017  Patient
             &        Johnson                                Assistance
             Johnso   &                                      Product
             n        Johnson                                Donation
             Patien   Plaza
             t        Kilmer
             Assist   Square,
             ance     Suite
             Founda   130 New
             tion     Brunswi
                      ck, NJ
                      08933
------------------------------------------------------------------------
Product     MAP      4700             $13,197    2/15/2017  Product
             Intern   Glynco                                 donation
             ationa   Parkway                                for
             l        Brunswi                                humanitaria
                      ck, GA                                 n
                      31525                                  assistance
                                                             (Medical
                                                             Mission
                                                             Packs).
------------------------------------------------------------------------
Product     MAP      4700            $125,592    2/14/2017  Product
             Intern   Glynco                                 donation
             ationa   Parkway                                for
             l        Brunswi                                humanitaria
                      ck, GA                                 n
                      31525                                  assistance
                                                             in Sierra
                                                             Leone
------------------------------------------------------------------------
Product     MAP      4700            $108,127   11/16/2017  Product
             Intern   Glynco                                 donation
             ationa   Parkway                                for
             l        Brunswi                                humanitaria
                      ck, GA                                 n
                      31525                                  assistance
                                                             in the
                                                             Eastern
                                                             Caribbean
------------------------------------------------------------------------
Product     MAP      4700             $19,241    7/31/2017  Product
             Intern   Glynco                                 donation
             ationa   Parkway                                for medical
             l        Brunswi                                mission
                      ck, GA                                 program
                      31525
------------------------------------------------------------------------
Product     MAP      4700            $868,191    6/22/2017  Product
             Intern   Glynco                                 donation
             ationa   Parkway                                for
             l        Brunswi                                humanitaria
                      ck, GA                                 n
                      31525                                  assistance
                                                             in Haiti,
                                                             Dominican
                                                             Republic,
                                                             and
                                                             Guatemala.
------------------------------------------------------------------------
Monetary    Acercam  P.O. Box          $5,000    4/26/2017  ContraSIDA
             iento    3820
             Hispan   Columbi
             o de     a, SC
             Caroli   29230
             na del
             Sur
------------------------------------------------------------------------
Monetary    ADAP     P.O. Box          $5,000     4/4/2017  ADAP
             Advoca   15275                                  Directory
             cy       Washing
                      ton, DC
                      20003
------------------------------------------------------------------------
Monetary    ADAP     P.O. Box          $5,000   10/16/2017  Improving
             Advoca   15275                                  Access to
             cy       Washing                                Care Among
                      ton, DC                                Formerly
                      20003                                  Incarcerate
                                                             d
                                                             Populations
                                                             with HIV/
                                                             AIDS under
                                                             the AIDS
                                                             Drug
                                                             Assistance
                                                             Program
                                                             (ADAP)
------------------------------------------------------------------------
Monetary    African- 1833             $75,000    7/20/2017  Black
             Americ   West                                   Treatment
             an       8th                                    Advocates
             Aids     Street                                 Network
             Policy   Suite                                  (BTAN)
             And      200 Los                                Advanced
             Traini   Angeles                                Development
             ng       , CA                                   Program
             Instit   90057
             ute
------------------------------------------------------------------------
Monetary    AIDS     6260              $3,000     4/4/2017  Linkage to
             Founda   Westpar                                Care
             tion     k Drive
             Housto   Suite
             n,       100
             Inc.     Houston
                      , TX
                      77057
------------------------------------------------------------------------
Monetary    AIDS     200 W.           $50,000     3/1/2017  Ensuring
             Founda   Jackson                                Access to
             tion     Blvd.,                                 HIV
             of       Suite                                  Prevention
             Chicag   2100                                   and Care in
             o        Chicago                                Illinois
                      , IL                                   through
                      60606                                  Policy
                                                             Monitoring
                                                             and
                                                             Advocacy
------------------------------------------------------------------------
Monetary    AIDS     400               $5,000     4/4/2017  HIV Case
             Outrea   North                                  Management
             ch       Beach                                  at AIDS
             Center   Street                                 Outreach
                      Fort                                   Center
                      Worth,
                      TX
                      76111
------------------------------------------------------------------------
Monetary    AIDS     820 N.            $5,000    8/17/2017  Driving
             Resour   Plankin                                Innovation
             ce       ton                                    in HIV
             Center   Ave.                                   Healthcare
             of       Milwauk                                Via ARCW
             Wiscon   ee, WI                                 HIV Medical
             sin      53203                                  Centers
------------------------------------------------------------------------
Monetary    AIDS     17982             $2,000     5/8/2017  HIV and
             Servic   Sky                                    Hepatitis C
             es       Park                                   Testing
             Founda   Circle,                                Program
             tion     Suite J
             Orange   Irvine,
             County   CA
                      92614
------------------------------------------------------------------------
Monetary    AIDS     1101            $200,000   12/19/2017  Transgender
             United   14th                                   Leadership
                      Street,                                Initiative
                      NW
                      Suite
                      300
                      Washing
                      ton, DC
                      20005
------------------------------------------------------------------------
Monetary    Alexian  825 W.            $5,000    8/17/2017  Transitional
             Brothe   Welling                                Living
             rs       ton                                    Program for
             Bonave   Chicago                                Homeless
             nture    , IL                                   Adults with
             House    60657                                  HIV/AIDS
------------------------------------------------------------------------
Monetary    Alivene  3808              $1,000    7/31/2017  Integrative
             ss       Nicolle                                Therapies
             Projec   t Ave                                  for People
             t,       Minneap                                Living with
             Inc.     olis,                                  HIV
                      MN
                      55409
------------------------------------------------------------------------
Monetary    Aunt     1101 N.           $2,500    7/11/2017  Project
             Rita's   Central                                HIVAZ
             Founda   Ave.
             tion     Suite
                      212
                      Phoenix
                      , AZ
                      85004
------------------------------------------------------------------------
Monetary    Caring   PO Box           $40,000    3/20/2017  General
             Ambass   1748                                   Hepatitis C
             adors    Oregon                                 Program
             Progra   City,                                  Support
             m, Inc   OR
                      97045
------------------------------------------------------------------------
Monetary    Catholi  119               $5,000     4/4/2017  The Home
             c        Dameron                                Place
             Charit   Avenue
             ies of   Knoxvil
             East     le, TN
             Tennes   37917
             see,
             Inc.
------------------------------------------------------------------------
Monetary    Center   1115 E.           $3,500   10/23/2017  HIV
             For      12th                                   Prevention
             Health   St.                                    Access and
             Empowe   Austin,                                Linkage to
             rment    TX                                     Care
             (CHE)    78702
------------------------------------------------------------------------
Monetary    Central  1785              $5,000   11/13/2017  HIV Testing,
             Louisi   Jackson                                Counseling,
             ana      Street                                 and
             Aids     Alexand                                Prevention
             Suppor   ria, LA                                for African
             t        71301                                  American
             Servic                                          Teens and
             es Inc                                          Young
             (CLASS                                          Adults
             )
------------------------------------------------------------------------
Monetary    Communi  1930             $20,000   12/18/2017  Equal Access
             ty       Martin
             Educat   Luther
             ion      King Jr
             Group    Avenue
                      SE
                      Washing
                      ton, DC
                      20020
------------------------------------------------------------------------
Monetary    Communi  1930             $20,000    3/13/2017  Access Tools
             ty       Martin                                 Linking All
             Educat   Luther                                 to Services
             ion      King Jr                                (ATLAS).
             Group    Avenue
                      SE
                      Washing
                      ton, DC
                      20020
------------------------------------------------------------------------
Monetary    Communi  575 8th          $15,000    7/20/2017  HIV Health
             ty       Avenue,                                Literacy
             Resear   Suite                                  Education
             ch       502 New                                and
             Initia   York,                                  Training
             tive     NY                                     for Service
             on       10018                                  Providers
             AIDS,                                           Working
             Inc.                                            with
                                                             Vulnerable
                                                             Populations
------------------------------------------------------------------------
Monetary    Frannie  30                $5,000   11/13/2017  Supportive
             Peabod   Danfort                                Pathways
             y        h St.                                  Along the
             Center   Suite                                  Care
             Inc.     311                                    Continuum
                      Portlan                                (SPACC)
                      d, ME
                      04101
------------------------------------------------------------------------
Monetary    Gay      446 W.           $30,000   12/19/2017  Peer
             Men's    33rd                                   Navigation
             Health   Street                                 for high-
             Crisis   New                                    risk and
                      York,                                  HIV-
                      NY                                     positive
                      10001                                  transgender
                                                             people
------------------------------------------------------------------------
Monetary    Gay      446 W.           $30,000     3/1/2017  Peer
             Men's    33rd                                   Navigation
             Health   Street                                 for high-
             Crisis   New                                    risk and
                      York,                                  HIV-
                      NY                                     positive
                      10001                                  transgender
                                                             people
------------------------------------------------------------------------
Monetary    Hepatit  35 East          $20,000     2/7/2017  The
             is C     38th                                   Hepatitis C
             Mentor   Street,                                Education
             and      Suite                                  and Support
             Suppor   #4G New                                Group
             t        York,                                  Assistance
             Group    NY                                     Program
             Inc.     10016
------------------------------------------------------------------------
Monetary    Hepatit  1261 S.          $35,000     2/8/2017  General
             is       Jackson                                Program
             Educat   St.,                                   Support
             ion      Suite
             Projec   201
             t        Seattle
                      , WA
                      98144
------------------------------------------------------------------------
Monetary    Howard   4025 N.          $25,000    9/29/2017  Patient
             Brown    Sherida                                Assistance
             Health   n                                      Clinic
             Center   Chicago                                (PAC):
                      , IL                                   Medication
                      60613                                  Therapy
                                                             Management
                                                             for
                                                             Underserved
                                                             Patients
------------------------------------------------------------------------
Monetary    Interna  2200             $75,000     3/1/2017  Conversation
             tional   Pennsyl                                Maps:
             Associ   vania                                  Patient
             ation    Avenue,                                Empowerment
             of       NW 4th                                 through HIV
             Physic   Floor                                  Peer
             ians     East                                   Dialogue in
             in       Washing                                Five U.S.
             AIDS     ton, DC                                Fast-Track
             Care     20037                                  Cities
             Inc.
------------------------------------------------------------------------
Monetary    Legacy   4054              $5,000    4/26/2017  Grace
             Counse   McKinne                                Project
             ling     y Ave.,                                Program for
             Center   Suite                                  Women
                      102                                    Living with
                      Dallas,                                HIV/AIDS
                      TX
                      75204
------------------------------------------------------------------------
Monetary    Legal    17 N.             $5,000    8/23/2017  Communities
             Counci   State                                  of Color
             l for    Street,                                Outreach
             Health   Suite                                  Program
             Justic   900
             e        Chicago
                      , IL
                      60602
------------------------------------------------------------------------
Monetary    Lifelon  P.O. Box          $3,000    3/20/2017  Living
             g Aids   80547                                  Positively
             Allian   Seattle
             ce       , WA
                      98108
------------------------------------------------------------------------
Monetary    Minorit  5149 W.           $7,500     4/4/2017  S.T.E.P.
             y AIDS   Jeffers                                Program
             Projec   on Blvd                                Strengtheni
             t        Los                                    ng
                      Angeles                                Treatment
                      , CA                                   Education
                      90016                                  for People
                                                             Living with
                                                             HIV/AIDS
------------------------------------------------------------------------
Monetary    Nationa  580             $175,000    3/16/2017  NATAP HIV
             l AIDS   Broadwa                                and HCV
             Treatm   y Suite                                Information
             ent      1010                                   and
             Advoca   New                                    Education
             cy       York,                                  Project
             Projec   NY
             t        10012
------------------------------------------------------------------------
Monetary    Nationa  580             $175,000   12/18/2017  NATAP HIV
             l AIDS   Broadwa                                and
             Treatm   y Suite                                Hepatitis
             ent      1010                                   Information
             Advoca   New                                    and
             cy       York,                                  Education
             Projec   NY                                     Project
             t        10012
------------------------------------------------------------------------
Monetary    Nationa  444             $150,000   12/19/2017  Affordable
             l        North                                  Care Act
             Allian   Capitol                                (ACA), Ryan
             ce of    Street                                 White/ADAP,
             State    NW #339                                Public
             and      Washing                                Policy and
             Territ   ton, DC                                Technical
             orial    20001                                  Assistance,
             AIDS                                            and the
             Direct                                          Minority
             ors                                             Leadership
                                                             Programs
------------------------------------------------------------------------
Monetary    NovaSal  2946              $2,500   11/15/2017  ``Increasing
             ud,      Sleepy                                 Testing and
             Inc.     Hollow                                 Improving
                      Rd.                                    Retention
                      Falls                                  in Care and
                      Church,                                Access to
                      VA                                     Treatment
                      22044                                  for People
                                                             at Risk or
                                                             Currently
                                                             Living with
                                                             HIV''
------------------------------------------------------------------------
Monetary    Palmett  2638 Two          $7,500    7/11/2017  HIV Care
             o AIDS   Notch                                  Coordinatio
             Life     Road,                                  n Program
             Suppor   Suite
             t        108
             Servic   Columbi
             es       a, SC
                      29204
------------------------------------------------------------------------
Monetary    Positiv  785               $2,500   11/13/2017  Integrated
             e        Market                                 Support
             Resour   Street,                                Services
             ce       10th
             Center   Floor
                      San
                      Francis
                      co, CA
                      94103
------------------------------------------------------------------------
Monetary    PowerSo  P.O. Box          $2,500   10/23/2017  Bridging the
             urce     12354                                  Gap
             Tucson   Tucson,
             , Inc.   AZ
                      85732
------------------------------------------------------------------------
Monetary    Project  273              $10,000   12/18/2017  Mission
             Inform   Ninth                                  Support
                      Street
                      San
                      Francis
                      co, CA
                      94103
------------------------------------------------------------------------
Monetary    Project  273              $10,000    6/26/2017  Mission
             Inform   Ninth                                  Support for
                      Street                                 Project
                      San                                    Inform
                      Francis
                      co, CA
                      94103
------------------------------------------------------------------------
Monetary    Project  273              $25,000    6/26/2017  HIV Care
             Inform   Ninth                                  Linkage,
                      Street                                 Retention
                      San                                    and Re-
                      Francis                                engagement
                      co, CA
                      94103
------------------------------------------------------------------------
Monetary    Project  273              $25,000    6/26/2017  Policy
             Inform   Ninth                                  Advocacy to
                      Street                                 Protect HIV
                      San                                    Treatment
                      Francis                                and Care
                      co, CA
                      94103
------------------------------------------------------------------------
Monetary    Project  2929 NE           $5,000   10/16/2017  ``Surviving
             Link     6TH                                    and
             of       Avenue                                 Thriving;
             South    Wilton                                 Long-term
             Florid   Manors,                                Survivors
             a,       FL                                     workshops,
             Inc.     33334                                  for Gay Men
                                                             50 and Over
                                                             Living with
                                                             HIV,'' and
                                                             for our
                                                             ``Long-term
                                                             Survivor''
                                                             support
                                                             group.
------------------------------------------------------------------------
Monetary    RAIN,    601 E.           $20,000    9/29/2017  Free On-Site
             Inc.     5th                                    Mental
                      Street,                                Health
                      Suite                                  Services
                      470 PO                                 for People
                      Box                                    Living with
                      37190                                  HIV
                      Charlot
                      te, NC
                      28202
------------------------------------------------------------------------
Monetary    San      1035             $25,000    6/27/2017  TransLife
             Franci   Market                                 HIV Care
             sco      Street,                                and Support
             AIDS     Suite
             Founda   400 San
             tion     Francis
                      co, CA
                      94103
------------------------------------------------------------------------
Monetary    Service  305 7th           $5,000    4/21/2017  SAGEPositive
             s and    Avenue,
             Advoca   15th
             cy For   Floor
             Gay      New
             Lesbia   York,
             n        NY
             Bisexu   10001
             al and
             Transg
             ender
             Elders
             Inc.
------------------------------------------------------------------------
Monetary    The      17 Davis         $65,000    7/20/2017  Ensuring
             AIDS     Bouleva                                Adequate
             Instit   rd,                                    Funding for
             ute      Suite                                  Domestic
                      403                                    HIV/AIDS
                      Suite                                  Programs
                      403
                      Tampa,
                      FL
                      33606
------------------------------------------------------------------------
Monetary    The      17 Davis         $65,000   12/19/2017  2018 Federal
             AIDS     Bouleva                                and State
             Instit   rd,                                    HIV/AIDS
             ute      Suite                                  Policy
                      403                                    Issues
                      Suite
                      403
                      Tampa,
                      FL
                      33606
------------------------------------------------------------------------
Monetary    The      64 West           $4,000    9/18/2017  ID Inspired
             Allian   35th                                   Challenge
             ce for   Street,
             Positi   3rd
             ve       Floor
             Change   New
                      York,
                      NY
                      10001
------------------------------------------------------------------------
Monetary    The      99                $5,000    7/11/2017  Expansion of
             Next     Bishop                                 Next Step's
             Step     Allen                                  Year-round
             Fund,    Drive                                  Programming
             Inc.     Cambrid                                for teens
                      ge, MA                                 and young
                      02138                                  adults
                                                             living with
                                                             HIV.
------------------------------------------------------------------------
Monetary    The San  P.O. Box          $2,500    8/18/2017  Youth
             Diego    3357                                   Services
             LGBT     San
             Commun   Diego,
             ity      CA
             Center   92163
------------------------------------------------------------------------
Monetary    The San  P.O. Box          $5,000    7/19/2017  HIV services
             Diego    3357
             LGBT     San
             Commun   Diego,
             ity      CA
             Center   92163
------------------------------------------------------------------------
Monetary    The      85               $30,000   12/18/2017  Building
             Well     Norman                                 H.O.P.E.
             Projec   Avenue                                 (Hopeful
             t        P.O.                                   Outreach
                      Box                                    and
                      220410                                 Positive
                      Brookly                                Engagement
                      n, NY                                  for Women
                      11222                                  Living with
                                                             HIV)
------------------------------------------------------------------------
Monetary    The      85               $30,000     3/1/2017  HIV Disease
             Well     Norman                                 Awareness/
             Projec   Avenue                                 Information
             t        P.O.                                   , Community
                      Box                                    Support,
                      220410                                 Advocacy
                      Brookly                                and
                      n, NY                                  Capacity
                      11222                                  Building
------------------------------------------------------------------------
Monetary    Treatme  90 Broad         $15,000    6/26/2017  Ending the
             nt       Street,                                Epidemic
             Action   Suite
             Group,   2503
             Inc.     New
                      York,
                      NY
                      10004
------------------------------------------------------------------------
Monetary    Univers  UCSF             $15,000    9/29/2017  UCSF
             ity Of   Allianc                                Alliance
             Califo   e                                      Health
             rnia     Health                                 Project
             San      Project                                Mission-
             Franci   1855                                   Based
             sco      Folsom                                 Support--Co
                      Street,                                mmunity
                      Ste.                                   Based
                      670 Box                                Intensive
                      0884                                   Case
                      San                                    Management
                      Francis                                for People
                      co, CA                                 Living With
                      94143                                  HIV/AIDS
------------------------------------------------------------------------
Monetary    Univers  620 W.            $2,500   11/13/2017  JACQUES
             ity Of   Lexingt                                Initiative
             Maryla   on St.                                 Community
             nd       2nd                                    Outreach
             Baltim   floor                                  Program
             ore      Baltimo
             Founda   re, MD
             tion,    21201
             Inc.
------------------------------------------------------------------------
Monetary    US       1300 PA         $725,000   12/19/2017  Global
             Agency   Avenue.                                Public
             for      , NW SA-                               Health
             Intern   44 Rm                                  Programs:
             ationa   475-J                                  Infection
             l        Washing                                Control
             Develo   ton, DC                                ($250,000),
             pment    20523                                  Anti-
                                                             Microbial
                                                             Resistance
                                                             ($300,000),
                                                             Pharmacovig
                                                             ilance
                                                             ($175,000)
------------------------------------------------------------------------
Monetary    Wellnes  2929 NE           $2,000   10/16/2017  Prevention
             s        6                                      for HIV
             Center   Avenue,                                Positive
             of       Suite B                                Heterosexua
             South    Wilton                                 l/Minority
             Florid   Manors,                                Outreach
             a,       FL                                     Program
             Inc.     33334
------------------------------------------------------------------------
Monetary    Young    4164              $5,000    7/19/2017  TruEvolution
             Schola   Brockto                                Community
             rs For   n Ave                                  Wellness
             Academ   Riversi                                Center
             ic       de, CA
             Empowe   92501
             rment
------------------------------------------------------------------------
Product     Johnson  One          $14,933,212   12/31/2017  Patient
             &        Johnson                                Assistance
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             ance     Suite
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             tion     Brunswi
                      ck, NJ
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------------------------------------------------------------------------
Product     Partner  1616          $1,018,932    3/31/2017  Product
             ship     Fort                                   Donation
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             Supply   Drive,                                 Horizons
             Chain    12th                                   global
             Manage   Floor                                  public
             ment     Arlingt                                health
                      on, VA                                 program
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Product     Partner  1616            $124,669     9/8/2017  Product
             ship     Fort                                   donation
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             Chain    12th                                   Global
             Manage   Floor                                  Public
             ment     Arlingt                                Health
                      on, VA                                 Program
                      22209-
                      3100
------------------------------------------------------------------------
Product     US       1300        $302,250,000   12/18/2017  Product
             Agency   Pennsyl                                donation
             for      vania                                  for global
             Intern   Avenue,                                public
             ationa   N.W.                                   health
             l        Washing                                programs
             Develo   ton, DC
             pment    20523
------------------------------------------------------------------------


  Actelion Pharmaceuticals US, Inc. Contribution Payments Made in 2018
------------------------------------------------------------------------
 Organization Information      Project Title      Paid Amount     Paid
------------------------------------------------------------------------
Westchester Medical        Girls' Night Out         $2,000.00   20180326
 Center Foundation
------------------------------------------------------------------------
Scleroderma Research       CONQUER Registry       $500,000.00   20180125
 Foundation                 Project
------------------------------------------------------------------------
Multiple Sclerosis         The Latest MS           $12,000.00   20180424
 Association of America     Research Updates
------------------------------------------------------------------------
Have a Ball Foundation     14th Annual ``Have a     $5,000.00   20180309
                            Ball'' Golf
                            Tournament
------------------------------------------------------------------------
CMDAT Research Foundation  Free seminars on         $1,400.00   20180411
                            pulmonary arterial
                            hypertension and
                            Gaucher disease in
                            the Greater Denver
                            area
------------------------------------------------------------------------
Echo Hill Outdoor School   Echo Hill Outdoor        $5,000.00   20180410
 Heart Camp 2018            School Heart Camp
                            2018
------------------------------------------------------------------------
Pulmonary Hypertension     Chicago Area Trivia      $3,200.00   20180510
 Association                Night
------------------------------------------------------------------------
American Lung Association  St. Louis Lung Force     $1,500.00   20180524
 in Missouri                Expo
------------------------------------------------------------------------
Pulmonary Hypertension     Thirsting for a Cure     $6,000.00   20180725
 Association
------------------------------------------------------------------------
UPHill Journeys            11th Annual Northern     $2,000.00   20180710
                            New England PH Forum
------------------------------------------------------------------------
Pulmonary Hypertension     Steps for Stripes Fun    $1,500.00   20180925
 Association                Walk
------------------------------------------------------------------------
American Heart             Ann Arbor-Jackson        $5,000.00   20181025
 Association                Heart Ball
------------------------------------------------------------------------
phaware global             PHAWARE CHARITY         $2,500.00   20181116
 association                POKER TOURNAMENT
------------------------------------------------------------------------
Pulmonary Hypertension     Georgia Fun Walk         $2,500.00   20181010
 Association
------------------------------------------------------------------------
American Lung Association  St. Louis Lung Force     $1,500.00  20181010
 in Missouri                Expo
------------------------------------------------------------------------
Actelion has also made financial donations to independent charitable
  foundations that assist patients who are underinsured and in financial
  need with treatment-related expenses. In keeping with our donor
  agreements and applicable regulatory guidance, we will only disclose
  aggregate data on our charitable giving and do not publicize
  information on donations to specific foundations and disease states.
  In 2018, we contributed approximately $50.2 million in donations to
  independent charitable foundations, enabling them to provide
  assistance with medication-related copays to patients with pulmonary
  hypertension.


                                 ______
                                 
     Submitted by Hon. John Thune, a U.S. Senator From South Dakota

                              340B Health

                     1101 15th Street NW, Suite 910

                          Washington, DC 20005

                          Phone: 202-552-5850

                           FAX: 202-552-5868

                           www.340bhealth.org

                340B is a Small Share of the Drug Market

                   and Does Not Increase Drug Prices

New data show drug manufacturers provided $6.1 billion in total drug 
discounts in 2015 under the 340B Program. The 340B discount is less 
than 2 percent of the total U.S. drug market and is dwarfed by other 
segments of the drug industry.

340B does not increase drug prices. 340B reduces costs for safety net 
providers, allowing them to provide affordable drugs and services to 
low-income patients.

[GRAPHIC(S) NOT AVAILABLE IN TIFF FORMAT]  


Compared to other segments of the market, the total 340B discount is:

      Less than 2 percent of total U.S. drug spending.
      3.6 percent of all discounts and rebates offered by 
manufacturers.
      4 percent of the specialty drug spending.
      89 percent less than the rebates manufacturers provide to health 
plans and PBMs.
      78 percent less than what manufacturers spend on advertising.
      57 percent less than what brand-name manufacturers have lost 
from patent expirations.

Nearly one third of the total 340B discount is due a penalty enforced 
against drug manufacturers for raising the price of drugs higher than 
the rate of inflation or voluntarily providing a discount lower than 
the 340B price. Manufacturers could avoid this penalty by not 
increasing their drug prices at such high rates.

                    Total 340B Discount, $6.1 Billion
------------------------------------------------------------------------
 
------------------------------------------------------------------------
Required by 340B Statute, $4.2 Billion             Inflationary Penalty,
                                                            $1.9 Billion
------------------------------------------------------------------------


The full analysis by Dobson Davanzo is available here: http://
www.340bhealth.org/files/340B_Financial_Impact_7_17.pdf.

                                 ______
                                 
                 Prepared Statement of Hon. Ron Wyden, 
                       a U.S. Senator From Oregon
    Prescription drugs did not become outrageously expensive by 
accident. It's not the result of a system too complicated for Americans 
to comprehend. Drug prices are astronomically high because that's where 
pharmaceutical companies and their investors want them. The brakes have 
come off pharmaceutical pricing, and American families are hurtling 
along in the passenger seat terrified of what comes next.

    Today the committee will hear uplifting stories about miracle 
cures, but it is morally repugnant when patients can't afford them. It 
is morally repugnant when ailing patients are forced to choose between 
filling that next prescription or putting food on the table, because 
they can't afford both. It is morally repugnant when patients are 
forced to skip doses.

    You Pharma executives are here because the way you do business is 
unacceptable and unsustainable. Ten companies accounted for half of all 
profts in the health-care sector last fall. Nine of those ten were drug 
manufacturers. All but one of today's witnesses represent companies on 
that list. Drug makers behave as if patients and taxpayers are unlocked 
ATMs full of cash to be extracted, and their shareholders are the 
customers they value above all else.

    Let's look at concrete examples, starting with AbbVie. AbbVie 
manufactures the top-selling prescription drug in America, the 
arthritis medication Humira. Over 6 years, the company doubled the 
price of a 12-month supply from $19,000 to $38,000. Can patients opt 
for a less-expensive alternative? No they cannot, because AbbVie 
protects the exclusivity of Humira like Gollum with his ring: thick 
cobwebs of patents, legal tricks, and shadowy deals with other drug 
makers, all to keep the cash flowing.

    I also want to address troubling information the committee recently 
uncovered. I'm holding AbbVie's proxy statement, a document every 
publicly traded company must file with the SEC. Page 37 shows that in 
2017, a portion of CEO Richard Gonzalez's multi-million-dollar bonus 
was directly tied to sales of Humira. It appears the same incentive was 
in place in 2015 and 2016.

    In fact, the committee's review shows that all of AbbVie's top 
executives had the same arrangement. Mr. Gonzalez is welcome to 
respond, but the implication of that incentive ought to be clear. From 
top down, AbbVie's leadership had reason to keep pushing prices and 
sales upward.

    Now on to Pfizer. Pfizer gets first prize for emptiest gesture on 
pricing in 2018. After stern Trump tweets last year, Pfizer said it 
would temporarily freeze prices. But once the President got his splashy 
headlines, his gaze turned elsewhere, and Pfizer's former CEO told 
investors it was back to ``business as normal.'' Another round of price 
hikes in 2019, including on its pain medication Lyrica. Lyrica's price 
has increased 163 percent since 2012. With this one drug, Pfizer raked 
in $4.5 billion in 2017.

    Merck: Merck gets second prize for emptiest gesture on pricing in 
2018. It made sweet-sounding promises after coming under criticism, but 
it cut prices for drugs that provide essentially no revenue to the 
company. Left untouched were the cash cows Keytruda and Januvia, which 
account for more than a quarter of Merck's revenue. It's like promising 
car shoppers a great deal, except the only discounted model on the lot 
is an Edsel.

    Sanofi: A company wringing more and more cash out of people with an 
incurable disease. In 2010, a vial of Sanofi insulin cost less than 
$100. In 2018 it cost nearly $300, and the company raised prices again 
in 2019. Considering that the landmark breakthrough on insulin came 
early in the roaring twenties, nothing could justify that sudden price 
increase nearly a century later. Diabetics who can't afford the costs 
are self-rationing and endangering their lives, but at least the 
investors are happy.

    AstraZeneca: A lesson in saying the quiet part out loud. In an 
interview earlier this year, CEO Pascal Soriot complained that his $12-
million salary made him ``the lowest-paid CEO in the whole industry.'' 
He said it was ``annoying to some extent.'' His company, meanwhile, 
continues to raise the price of Symbicort, its $3-billion asthma drug. 
For some asthmatics, being able to breathe costs hundreds of dollars a 
month.

    Johnson & Johnson: A record-setting flip-flop. This January 7th, at 
the JP Morgan Healthcare Conference, CEO Alex Gorsky said that the 
pharmaceutical industry needed to self-police on pricing. Sounds good, 
but it didn't last long. Three days later, his company hiked the prices 
of hundreds of its drugs, including drugs that account for billions in 
Medicare spending.

    Bristol-Myers-Squibb: In 2017, the company spent roughly $11.5 
billion on dividends, stock buybacks, marketing, sales, and 
administrative costs. That's roughly triple the amount it spent on R&D.

    This is all a stark illustration of drug makers' profiteering and 
two-faced scheming. The central argument that the committee will hear 
in response is that the fault is everybody else's. The health plans are 
at fault. The PBMs are at fault. Regulators are at fault. They always 
point the finger elsewhere.

    We'll also hear that list prices don't matter; that the true costs 
are complicated. But companies don't set and raise list prices for fun. 
Those prices are directly tied to the amount patients pay out-of-pocket 
at the pharmacy window. They are directly tied to what taxpayers spend 
on health-care programs.

    Next, drug makers point fingers at the middlemen, pharmacy benefit 
managers. I've said for years that PBMs are wasteful and secretive, 
taking their cut without proving their worth to anybody. They will have 
their day before this committee. But PBMs don't set list prices; 
manufacturers do. Furthermore, manufacturers don't offer rebates for 
nearly 40 percent of Part D brand-name drugs. Those prices continue to 
rise. That's on the drug companies, not on PBMs.

    Next, drug makers say changes in the status quo will hurt R&D. A 
quick look at these companies' finances, on both sides of the balance 
sheet, shows that isn't the case. Revenue generated from American 
patients alone dwarfs what they spend on R&D worldwide. Drug makers 
also spend as much, if not more, on flashy TV ads and office-to-office 
salesmen as they spend on R&D. And if lower prices would diminish R&D, 
why don't costly dividends? Why don't stock buybacks? Is the stock 
price more important than inventing the next miracle cure?

    Even if you buy the specious argument that a drug's list price at 
launch is driven by the cost of R&D, what could justify arbitrary price 
increases year after year, long after the R&D spending is done?

    Finally, companies say they help patients afford drugs with 
``coupons`` or patient assistance programs. But if these programs are 
so widely generous, why can't drug makers instead simply lower prices 
across the board? Because it's just more slick branding--ploys that 
allow companies to maintain the status quo.

    One final point. I was there when seven Big Tobacco CEOs testifed 
in a committee room like this one, and they lied. The chairman and I 
expect better this morning. Your profits are outsized compared to 
others in the industry, you receive a massive portion of your revenue 
from American taxpayers, and you bear none of the consequences of high 
drug prices. It's past time to get beyond the excuses and make 
prescription drugs affordable.

                                 ______
                                 

                             Communications

                              ----------                              


                                  AARP

                            601 E Street, NW

                          Washington, DC 20049

 202-434--2277 | 1-888-OUR-AARP | 1-888-687-2277 | TTY: 1-877-434-7598

  www.aarp.org | twitter: @aarp | facebook.com/aarp | youtube.com/aarp

February 26, 2019

The Honorable Chuck Grassley        The Honorable Ron Wyden
Chairman                            Ranking Member
Committee on Finance                Committee on Finance
U.S. Senate                         U.S. Senate
219 Dirksen Senate Office Building  219 Dirksen Senate Office Building
Washington, DC 20510                Washington, DC 20510

Dear Chairman Grassley and Ranking Member Wyden:

AARP appreciates your focus on prescription drug prices and the 
challenges that increasing drug costs pose for seniors, and we thank 
you for holding the hearing on February 26, 2019, to highlight rising 
prescription drug prices. AARP, with its nearly 38 million members in 
all 50 states, the District of Columbia, and the U.S. territories is a 
nonpartisan, nonprofit, nationwide organization that helps people turn 
their goals and dreams into real possibilities, strengthens communities 
and fights for the issues that matter most to families such as 
healthcare, employment and income security, retirement planning, 
affordable utilities and protection from financial abuse.

Prescription drug prices are a high priority for AARP and all older 
Americans, as older adults are particularly vulnerable to high 
prescription drug prices. Medicare Part D enrollees take an average of 
4.5 prescriptions per month, and over two-thirds have two or more 
concurrent chronic illnesses. When older Americans talk about the 
impact of high prescription drug prices, they are often talking about 
costs that they will face every year for the rest of their lives.

Most Medicare beneficiaries live on modest incomes, with an annual 
median of just over $26,000. One-quarter have incomes of just over 
$15,000. One-quarter have less than $15,000 in savings. This is not a 
population that has the resources to absorb rapidly escalating 
prescription drug prices, and many are simply unable to afford the 
medications they need.

Unfortunately, older Americans have seen their prescription drug prices 
skyrocket in recent years. About 30 years ago, the public was outraged 
over a drug that cost less than $10,000 per year. We now have drugs 
with prices approaching $1 million per year.

In 2015, the average annual cost for a single specialty drug used on a 
chronic basis was $52,486--which is only slightly less than the median 
household income in the United States.\1\ We strongly support efforts 
to bring new treatments to market, but innovation is meaningless if 
patients cannot afford to use the treatment.
---------------------------------------------------------------------------
    \1\ https://www.aarp.org/content/dam/aarp/ppi/2017/11/full-report-
trends-in-retail-prices-of-specialty-prescription-druqs-widely-used-by-
older-americans.pdf.

AARP has been tracking the prices of widely-used prescription drugs 
since 2004. Our most recent Rx Price Watch Report focused on brand-name 
drugs and found that their retail prices increased by an average of 
8.4% in 2017--four times the rate of inflation. AARP's report also 
examined how drug companies' relentless price increases add up over 
time and found that the average annual cost of one brand-name drug--now 
around $6,800--would have been just under $2,200 in 2017 if retail 
price changes had been limited to general inflation between 2006 and 
2017.\2\
---------------------------------------------------------------------------
    \2\ https://www.aarp.org/content/dam/aarp/ppi/2018/09/trends-in-
retail-prices-of-brand-name-prescription-druqs-year-end-update.pdf

The average annual price increases for brand name drugs have exceeded 
the corresponding rate of inflation every year since at least 2006. 
More importantly, this problem goes beyond a few bad actors: virtually 
---------------------------------------------------------------------------
all of the manufacturers we track raise their prices every single year.

As a result, it is hardly surprising that our members consistently tell 
us they cannot afford the medications they need and are forced to make 
difficult choices as a result. Even less surprising is that they want 
this situation to change. Last year, in AARP's 2018 Mid-Term Voter 
Issues Survey, 92 percent of voters age 50 and older told us that 
candidates' positions on lowering drug costs was important to them, 
with 74 percent saying ``very important.''

Moreover, in a Kaiser 2018 Health Tracking Poll, prescription drug 
prices topped the list of the public's priorities, with 90 percent 
calling it an important priority, and 52 percent listing it as a ``top 
priority.'' In that poll, a large majority (80 percent) of the public 
reported perceiving prescription drug costs as ``unreasonable,'' a 
share that has increased since 2015.

Today it seems that prescription prices are in a never-ending race to 
the top. High priced specialty drug approvals have exceeded traditional 
drug approvals since 2010, and the number of people using such drugs is 
growing. Meanwhile, the research pipeline is full of products like 
orphan drugs, biologics, and personalized medicines that face little 
competition and will undoubtedly command even higher prices.

We have also seen massive increases in Medicare spending on 
prescription drugs. Between 2005 and 2016, Medicare Part B drug 
spending more than doubled from $12 billion to $29 billion. Total 
Medicare Part D spending is approaching $150 billion. These escalating 
costs will eventually result in higher taxes, cuts to vitally important 
public programs, or both.

Current prescription drug price trends are simply not sustainable. High 
and growing drug prices are affecting all Americans in some way. Their 
cost is passed along to everyone with health coverage through increased 
health care premiums, deductibles, and other forms of cost-sharing. 
They are also driving larger cost increases for a variety of taxpayer-
funded programs. Meanwhile, drug companies are working very hard to try 
to shift the blame to others in the health care system, leaving them 
free to set incredibly high prices and increase them with little 
restraint.

It is long past time for Congress to take action to rein in high drug 
prices. Thoughtful bipartisan efforts to help reduce prescription drug 
prices could save tens of billions of dollars for patients, taxpayers 
and the U.S. health care system. More importantly, they will help 
ensure that all Americans have affordable access to the drugs that they 
need to get and stay healthy.

We look forward to working with this Committee to find solutions that 
will lower prescription drug prices and costs for older Americans. If 
you have any additional questions, feel free to contact me or have your 
staff contact Amy Kelbick on our Government Affairs staff at 
[email protected] or 202-434-2648.

Sincerely,

Joyce A. Rogers
Senior Vice President
Government Affairs

                                 ______
                                 
          American Society of Health-System Pharmacists (ASHP)

                   4500 East West Highway, Suite 900

                           Bethesda, MD 20814

                          Email: [email protected]

                          Phone: 301-664-8692

ASHP (American Society of Health-System Pharmacists) respectfully 
submits the following statement for the record to the Senate Committee 
on Finance hearing on ``Drug Pricing in America: A Prescription for 
Change, Part II.''

ASHP represents pharmacists who serve as patient care providers in 
acute and ambulatory settings. The organization's nearly 50,000 members 
include pharmacists, student pharmacists, and pharmacy technicians. For 
more than 75 years, ASHP has been at the forefront of efforts to 
improve medication use and enhance patient safety.

ASHP's vision is that medication use will be optimal, safe, and 
effective for all people all of the time. A primary tenet of that 
vision includes access to affordable medications needed to save or 
sustain lives. Addressing the issue of skyrocketing drug prices, 
including excessive price increases on commonly used generic 
medications, is one of ASHP's highest and longstanding public policy 
priorities. According to a Kaiser Health Tracking Poll, 1 in 4 
Americans cannot afford their medications.\1\ Poor access to 
medications can lead to increased morbidity and mortality, and can 
cause healthcare costs to increase.
---------------------------------------------------------------------------
    \1\ DiJulio, Bianca, et al. ``Kaiser Health Tracking Poll: August 
2015.'' The Henry J. Kaiser Family Foundation, 20 Aug. 2015, 
www.kff.org/health-costs/poll-finding/kaiser-health-tracking-poll-
august-2015/. Accessed February 10, 2019.

ASHP has been proactively addressing challenges related to the rapid 
increase of prescription drug pricing on several fronts, including 
working with like-minded stakeholders and educating members of Congress 
about the unsustainable burdens faced by patients, healthcare 
---------------------------------------------------------------------------
providers, and the entire healthcare system.

ASHP is a lead member of the Steering Committee of the Campaign for 
Sustainable Rx Pricing (CSRxP), a coalition of prominent national 
organizations representing physicians, consumers, payers, hospitals, 
health systems, and patient advocacy groups. CSRxP has developed a 
policy platform promoting market based solutions supported by three 
pillars: competition, value, and transparency.

The goal of the campaign is to identify policy options that have 
bipartisan support and, therefore, a greater likelihood of passage. To 
that end, CSRxP focuses on policies to incentivize a more competitive 
marketplace to help stimulate lower drug prices. The campaign has also 
expressed support for efforts to loosen restrictions that prevent 
generic drug companies from obtaining the samples necessary to 
manufacture a competing product.

The price increases have placed enormous budgetary pressure on 
healthcare organizations, including hospitals and health systems. ASHP, 
along with the American Hospital Association (AHA) and the Federation 
of American Hospitals (FAH), recently released a report on the impact 
that the cost of and access to prescription drugs are having on 
hospital budgets and operations.

Specifically, the report showed that:

      Average total drug spending per hospital admission increased by 
18.5% between fiscal years (FY) 2015 and FY2017.

      Outpatient drug spending per admission increased by 28.7%, while 
inpatient drug spending per admission increased by 9.6%, between FY2015 
and FY2017.

      Hospitals experienced price increases of over 80% across 
different classes of drugs, including those for anesthetics, parenteral 
solutions, and chemotherapy.

      Over 90% of surveyed hospitals reported having to identify 
alternative therapies to manage spending.

      One in 4 hospitals had to cut staff to mitigate budget 
pressures.\2\
---------------------------------------------------------------------------
    \2\ NORC at the University of Chicago. ``Recent Trends in Hospital 
Drug Spending and Manufacturer Shortages'' (2019), https://www.aha.org/
system/files/2019-01/aha-drug-pricing-study-report-01152019_1.pdf. 
Accessed 25 Feb. 2019.

ASHP does not collect, store, or report drug pricing information. 
However, we continually hear from pharmacy leaders in hospitals and 
health systems that sudden, inexplicable, and unpredictable price 
increases in connection with some of the most commonly used, long 
standing generic medications are becoming more prevalent--and are 
---------------------------------------------------------------------------
occurring on a nationwide basis.

As there is no single solution to spikes in the prices of certain 
drugs, there is no single cause either. In this statement, we address 
four additional issues as they relate to drug pricing: competition, 
Risk Evaluation and Mitigation Strategies (REMS), Direct and Indirect 
Remuneration (DIR Fees), and the 340B Drug Pricing Program.

COMPETITION

In particular, ASHP would like to learn more about the marketplace 
dynamics that could contribute to this issue, as we have worked 
diligently to address the issue of drug shortages for nearly 15 years. 
Although drug shortages are caused by a number of factors, we have 
observed that drugs in short supply made by only one or two 
manufacturers often result in higher-than-normal prices. If, for 
example, there is a lack of competition in the generic market place, we 
urge the committee to look at ways to stimulate more marketplace 
presence. ASHP supports bills such as S. 64, the ``Preserve Access to 
Affordable Generics and Biosimilars Act.'' This bipartisan bill would 
potentially increase competition by prohibiting companies from engaging 
in ``pay-to-delay'' tactics to stifle generic and biosimilar entry into 
the market.

RISK EVALUATION AND MITIGATION STRATEGY (REMS)

ASHP recognizes that there may be limited circumstances in which 
constraints on the traditional drug supply system may be appropriate 
for reasons of patient safety, including through the use of 
manufacturer-driven REMS. However, we believe that REMS should never be 
used to artificially inflate drug prices, nor should REMS interfere 
with the professional practice of pharmacists, physicians, nurses, and 
other providers. We believe that there may be current cases in which a 
manufacturer-
driven REMS using restricted distribution is causing higher prices for 
those drugs, having adverse effects on patient access, and delaying 
treatment. In some cases, there may be evidence to suggest that the use 
of restricted or limited distribution channels has resulted in the 
inability of a potential competitor to acquire enough of a drug to 
conduct the required testing to bring a generic competitor to market. 
For this reason, ASHP thanks Chairman Grassley for introducing S. 340, 
the ``Creating and Restoring Equal Access to Equivalent Samples 
(CREATES) Act of 2019.'' The CREATES Act will help ensure that brand-
name pharmaceutical companies cannot manipulate regulatory rules to 
prevent competition, which is essential for patient access to 
affordable medications. Additionally, we recommend that Congress 
require the Food and Drug Administration (FDA) to investigate 
restricted distribution under a REMS as a means to artificially 
increase drug prices and limit access to critical medications. 
Restricting distribution of medications is often a means to push 
patients to a specific purchasing channel, which in some cases 
increases not only their out-of-pocket costs, but also systemic costs. 
Further, restricted distribution networks can complicate patient access 
to critical medications, potentially disrupting care.

DIRECT AND INDIRECT REMUNERATION FEES (DIR FEES)

Many factors contribute to high drug product costs; addressing the 
problem is made difficult by lack of transparency about the marketplace 
for those products. For example, DIR fees and other rebates negotiated 
by pharmacy benefit managers (PBMs) make it difficult to determine the 
actual cost of a drug. DIR fees are a growing nationwide concern among 
pharmacies that dispense medications in a community pharmacy or 
outpatient clinic setting. Created under the Medicare Part D Program, 
DIR fees were originally intended as a way for CMS to account for the 
true cost of the drug dispensed, including any manufacturer rebates. 
Often these rebates were unknown until the drug was dispensed and the 
claim adjudicated. Moreover, the fees themselves, which are often 
arbitrary in nature, have mushroomed over the past decade, to the point 
that pharmacies regularly see annual DIR totals in the tens of 
thousands of dollars.

Recently, a concerning trend has emerged in which pharmacy benefit 
managers (PBMs) have begun to charge DIR fees to their pharmacy 
providers. Under this scenario, PBMs are inappropriately applying their 
own plan performance measures as a way to assess fees on pharmacies. 
This is problematic for the following reasons:

      It is an arbitrary and unintended application of quality 
measures meant for total plan performance as opposed to pharmacy-level 
metrics.

      The quality measures applied tend to be based on maintenance 
medications such as blood pressure medications or medications used to 
treat diabetes. These measures were never intended to be applied to 
specialty medications or to other specialized disease states such as 
oncology, yet PBMs assess DIR fees against the gross reimbursement for 
all prescriptions received by pharmacy providers, not just maintenance 
medication s.

      Pharmacy providers are essentially being penalized with backdoor 
fees without any requirement that PBMs define, justify, or explain 
these charges to providers and to CMS.

DIR fees assessed on pharmacies providing specialty medications have 
been especially hard-hit, due to the fee structure. Fees could be a 
flat rate of per dollar per claim or a percentage (typically 3-9%) of 
the total reimbursement per claim. Using the percentage-based 
structure, the fees would increase markedly for specialty drugs, which 
are typically much more expensive than maintenance medications, 
sometimes resulting in thousands of dollars. A 9% fee on a drug costing 
$100,000 is $9,000. Additionally, these fees are assessed 
retroactively, sometimes months after the claim has been adjudicated, 
providing no recourse for the pharmacy impacted by the assessment.

The result of imposing DIR fees has led to higher cost-sharing 
responsibilities for Medicare beneficiaries, which have, in turn, 
caused more of these beneficiaries to enter the Part D donut hole, 
where the patient is solely responsible for the cost of the drug. Along 
with the higher costs absorbed by patients, adherence rates tend to be 
lower among Medicare beneficiaries who are in the donut hole and may 
not have the financial resources to pay for their medications. This is 
in stark contrast to the very reason DIR fees targeting manufacturer 
rebates were created--so that savings could be passed on to patients.

Pharmacies are not alone in their concern. In January 2017, CMS 
published a fact sheet expressing concern over DIR fees and cited those 
fees as contributing to increased drug costs, which, in turn, increased 
patients' out-of-pocket spending and Medicare spending overall.\3\ 
Additionally, questions remain as to whether Part D plan sponsors have 
the authority to assess these fees on pharmacies. There are no 
references to DIR fees collected on pharmacies in either the Part D 
statute or corresponding CMS regulations.
---------------------------------------------------------------------------
    \3\ Fact sheet, ``Medicare Part D--Direct and Indirect Remuneration 
(DIR).'' Centers for Medicare and Medicaid Services, 19 January. 2017, 
https://www.cms.gov/newsroom/fact-sheets/medicare-part-d-direct-and-
indirect-remuneration-dir. Accessed February 10, 2019

---------------------------------------------------------------------------
ASHP's professional policy on DIR fees is as follows:

        To advocate that payers and pharmacy benefit managers be 
        prohibited from recovering direct and indirect remuneration 
        fees from pharmacies on adjudicated dispensing claims; further,

        To oppose the application of plan-level quality measures on 
        specific providers, such as participating pharmacies.\4\
---------------------------------------------------------------------------
    \4\ ASHP Policy 1814, ``Direct and Indirect Remuneration Fees.''
---------------------------------------------------------------------------

THE 340B DRUG PRICING PROGRAM

For 25 years, the federal 340B program has allowed safety-net hospitals 
``to stretch scarce Federal resources as far as possible, reaching more 
eligible patients and providing more comprehensive services.'' This 
program has been essential to expanding access to lifesaving 
prescription drugs and comprehensive healthcare services to low-income 
and uninsured individuals, at no cost to the federal government. The 
federal 340B program is not causing high drug prices. The program 
accounts for less than 5% of annual drug purchases in the United 
States, while safety-net providers give 30% of the care. There are many 
contributing factors to higher drug costs, but there is no objective 
evidence that the program has increased overall drug pricing. In fact, 
the 340B program is revenue-neutral, benefiting patients without 
increasing costs for federal payors.

The federal 340B program enables these hospitals to serve their 
communities by providing vital care such as:

      Free or lower-cost medications to patients.
      Programs to increase medication adherence, including clinical 
pharmacy services to high-risk patients who are on multiple and/or 
complex medications.
      Increased access to primary care.
      Screenings and preventive care services to detect health 
problems early and decrease morbidity and mortality, as well as to 
decrease healthcare costs and hospital admissions.

The federal 340B program is at risk because of a recent change in 
Medicare payment policy that reduces payment from average sales price 
plus 6 percent to average sales price minus 22.5 percent. Cuts of this 
magnitude undermine the intent of the program, reducing resources that 
hospitals use to expand access to care and services to vulnerable 
communities. Given the increasingly high cost of pharmaceuticals, the 
federal 340B program provides critical support to the entities eligible 
to participate in the program.

CONCLUSION

ASHP thanks the Committee on Finance for holding this important 
hearing. ASHP remains committed to working with Congress and industry 
stakeholders to ensure that patients have affordable access to 
lifesaving and life-sustaining medications.

                                 ______
                                 
              Coalition for Affordable Prescription Drugs
U.S. Senate
Committee on Finance
Dirksen Senate Office Bldg.
Washington, DC 20510-6200

Tuesday, February 26, 2019

The Coalition for Affordable Prescription Drugs (CAPD) appreciates the 
opportunity to submit the following statement for the record.

Overview

CAPD is a diverse group of employers, unions, public sector employees 
and retirees and the pharmacy benefit managers (PBMs) they partner with 
to provide more affordable prescription drug coverage for millions of 
Americans.

Today, too many patients and families are struggling to pay for the 
medications they need. It's no surprise that a recent Politico/Harvard 
Chan School of Public Health poll showed that 80 percent of Americans 
see high prescription drug prices as a top priority for the new 
Congress and the Administration.

The Role of PBMs in Lowering Costs

In the face of rising drug prices, PBMs partner with employers, unions, 
public sector retirees and other organizations who purchase health care 
to help manage prescription drug coverage for millions of Americans. By 
negotiating with drug companies and providing patient-centered tools to 
improve care and help lower out-of-pocket costs, PBMs save over $900 
per person each year.

In addition, PBMs are expanding visibility into drug prices by enabling 
doctors and patients to see the price of various medicines at the point 
of prescribing, based on the individual's specific drug benefits. With 
this information, physicians switch to a more affordable medicine 
nearly 20 percent of the time when clinically equivalent alternatives 
are offered through UnitedHealth Group's RTBT, PreCheck MyScript. In 
another example, CVS Health's Real Time Benefits tool has saved 
patients an average of $120 to $130 per fill.

Drug Company Prices Are the Problem

Although there have been many ideas proffered about how to address the 
rising prices of medicines, CAPD believes that we first need to address 
the root problem: prices set by drug makers. Drug companies alone set 
their prices and they are rising at an unsustainable rate. In fact, 
drug companies have raised prices already in 2019 on hundreds of 
medicines. And, what's worse is that this is repeat behavior. Drug 
companies often raise those prices multiple times a year for the exact 
same product. Over the last five years, prices increased on the top 20 
most prescribed brand-name drugs for seniors by an average of 12 
percent each year, which is significantly above the annual rate of 
inflation. The truth is simple: Drug companies hike their prices 
because they can. When they do so, millions of patients pay more at the 
counter.

Drug companies, hoping to avoid scrutiny and sustain high profits, are 
pointing the finger at every other industry except themselves. 
According to drug companies, the reason why drug prices are so high 
isn't because they keep raising prices, or abuse the patent system, or 
make by far the highest profits in health care--it's everyone else's 
problem, not theirs.

In today's testimony, we will likely hear a common refrain from drug 
companies: part of the reason that drug prices are so high are because 
of the rebates that they are forced to give to PBMs. But the problem 
with this argument is that, according to a recent study, there is 
little correlation between prices drug companies set for their drugs 
and the rebates negotiated by PBMs across 23 major drug categories. 
What's more, in Medicare Part D, even after accounting for rebates, the 
costs of brand name drugs still increased 62% from 2011 to 2015.

All parties need to come to the table to make prescriptions more 
affordable and accessible to the patients who need them--but nothing 
will be done if pharma refuses to even pull up a chair and address the 
problem where it starts: their high prices. We hope Congress will use 
this hearing as an opportunity to ask the pharmaceutical industry to 
answer for these increases.

Pharma's Gamesmanship Reducing Competition to Keep Prices High

One way to meaningfully lower drug prices for patients is to stop the 
gamesmanship of the patent and regulatory systems that drug companies 
use to maintain their monopoly pricing power and keep lower-cost 
generic alternatives from entering the market.

Brand drug manufacturers exploit the FDA Risk Evaluation and Mitigation 
Strategies (REMS) program to prevent generic drug makers from accessing 
needed samples, costing the U.S. health care system $5.4B each year. 
The CREATES Act, which passed out of the Senate Judiciary Committee 
last year, is a targeted, market-based, bipartisan solution to the 
longstanding problem of brand name pharmaceutical companies denying 
generic manufacturers access to the samples they require to conduct 
necessary equivalence testing to bring their product to market.

Another way brand drug manufacturers game the patent and regulatory 
system is through ``pay-for-delay'' deals, in which drug makers engage 
in anticompetitive patent settlements with potential generic 
competitors, resulting in $3.58 in higher drug costs each year. In the 
most high-profile example of these abuses, drug maker AbbVie last year 
reached agreements with Amgen, Samsung Bioepis and Mylan to delay entry 
of a lower-cost biosimilar version of the drug to 2023 in the United 
States.

A third example of gamesmanship by brand drug manufacturers is 
evergreening, in which generic competition is delayed by additional 
patents on minor variations of the original drug for the clear purpose 
of extending monopoly protection. While these tweaks often do not 
convey enhanced clinical benefits to the patient, they do extend the 
time period during which drug manufacturers can continue to control 
pricing by preventing competition. For example, best selling drug 
Humira to treat rheumatoid arthritis and psoriasis is protected by over 
100 patents and the product may not face any competition until as late 
as 2034.

We encourage Congress to explore proposals that target patent and 
regulatory abuses by drug companies in order to lower drug prices for 
patients.

Conclusion

Simply put, a patient cannot be helped by a drug they cannot afford. We 
ask today that Congress once and for all refuse to accept drug 
manufacturers' excuses for high prices and take steps to put an end to 
the patent and regulatory abuses that keep prices artificially high.

We believe the time to act is now. CAPD is committed to working with 
Congress and other stakeholders on this and other solutions to 
meaningfully lower prescription drug prices for all Americans. We look 
forward to supporting this critical effort.

Debra Barrett
Executive Director, Coalition for Affordable Prescription Drugs

Contact:
Meghan Scott
Spokesperson, Coalition for Affordable Prescription Drugs
[email protected]
(202) 341-2060

           What They're Saying: Don't Let Pharma Off the Hook

On January 29, the Senate Finance Committee held a hearing, ``Drug 
Pricing in America: A Prescription for Change.'' During the hearing, 
both Senators and witnesses discussed drug companies' high prices and 
their anti-competitive actions.

DRUG COMPANIES' HIGH PRICES

      Chairman Chuck Grassley (R-Iowa): ``I've also heard from seniors 
who have seen their prescriptions increase month after month for no 
apparent reason. And I've heard stories about people reducing their 
life-saving medicines...to save money. This is unacceptable. . . . But 
other drugs are creating problems as well, that is why tackling high 
prescription drug costs is one of Senator Wyden's and my first priority 
on this committee.''
      Ranking Member Ron Wyden (D-Oregon): ``So there's no shortage of 
evidence about what the problems are. The companies have unchecked 
powers to set prices on their own, and often it's to meet Wall Street's 
expectations rather than meet demand in the market.''
      Mark Miller, The Arnold Foundation: ``The revenues that come out 
of the United States exceed R&D by something like 70, 75 percent. . . . 
So the first point is when people say R&D is driving these prices, 
there is a big disconnect in there. . . . We found many companies in 
which they're spending much more on advertising, marketing and other 
administrative expenses than they are on R&D.''
      Peter Bach, Memorial Sloan Kettering: ``Prices for monopoly 
goods such as these are determined by the market in which they are 
sold, not the other way around. . . . Please realize that these drugs 
do not inherently cost $1 million any more than they inherently cost 
$1.''
      Kathy Sego, mother of a child with diabetes: ``As a mother, I 
would probably say to them--I hope you know that there are people who 
are going without their medication, and because they're going without 
their medication they're at risk of dying. And how can you be OK with 
that? . . . That should never be a decision that a person needs to 
make. And unfortunately, it is.''

GAMESMANSHIP AND ANTICOMPETITIVE PRACTICES

      Douglas Holtz-Eakin, American Action Forum: ``We have some very 
isolated instances of cost associated with off-patent sole-source 
drugs. And in those circumstances, it appears that firms are able to 
take advantage of their market power and raise the prices of drugs 
sharply. This strikes me as a fundamental anti-competitive act that 
ought to be investigated.''
      Senator Robert Menendez (D-New Jersey): ``Manufacturer coupons, 
many suggest, distort spending. . . . Who's winning with these 
coupons?'' Peter Bach: ``I can assure you we know who's winning and 
it's the people who are printing the coupons . . . the reality is 
they're artificial price supports.''
      Senator Maggie Hassan (D-New Hampshire): ``We've seen a lot of 
bad actors gaming the system over the years, really to pad their 
pockets. There are countless ways drug companies take advantage of 
loopholes and taxpayers end up footing the bill.''
      Mark Miller: ``We need to curb the anticompetitive behaviors of 
manufacturers and inject competition back into the marketplace. 
Manufacturers benefit from taxpayer-funded NIH research and from 
government granted monopolies. And naturally, they devote resources to 
protecting those monopolies.''

                    AffordablePrescriptionDrugs.org

                                 ______
                                 
                    Letter Submitted by Linda George
March 4, 2019

U.S. Senate
Committee on Finance
Dirksen Senate Office Bldg.
Washington, DC 20510-6200

RE: ``Drug Pricing in America,'' Senate hearing held on February 26, 
2019

    Dear Finance Committee:

    On Wednesday January 23, 2019, I gave myself my last weekly 
injection of Humira, which had helped my mobility due to psoriatic 
arthritis. I have done very well for the past two years with this 
drug--one typically requiring a biweekly 40mg syringe injection. But I 
just started a new medication, an infusion administered in my doctor's 
office by an outsourced nurse who's not part of the practice.

    I needed to switch to the infused medication because on March 1st--
when I became eligible for Medicare--Humira would increase from $5/
monthly under our previous private insurer, Anthem Blue Cross, to a 
prohibitive $800+ per injection with Medicare Part D coverage. Bottom 
line: Medicare does not cover self-injections. Because an infusion 
would be administered in my rheumatologist's office, it is 100% covered 
as a medical procedure through Part B via Medicare. Now, I understand 
why Humira's advertisements, invading my television screen no matter 
what time or what channel I watch, always feature younger people 
engaged in various physical activities.

    When I needed information about how to navigate this insurance 
morass, I called my Humira ambassador, an AbbVie employee who serves as 
a liaison between the consumer and the company. She assured me that I 
may be covered if I submitted my tax returns to the company's 
foundation. Evidently if I make less than $65,000, through the 
company's assistance program, the parent company's foundation pays a 
portion of the thousands needed to offset consumers' exorbitant cost of 
this drug; however, regardless of my income, I have a huge problem 
submitting my tax statements to anyone--except to my trusted accountant 
and the IRS.

    It seems AbbVie puts some big money into tiers of bureaucracy 
through advertising, marketing, and supporting a foundation based on 
employees forced to donate a percentage of their income. In addition, 
whenever a consumer needs to have the simplest question answered by the 
company, instead of AbbVie offering an 800 phone number, that consumer 
must first enroll in the ``Ambassador Program,'' then wait for their 
designated ambassador to return the call. I've had two ambassadors so 
far, and each seems more than willing to keep me on the phone for an 
extended time, asking all kinds of questions, as if padding their own 
positions by calling consumers on a monthly basis. I'd much prefer that 
these ambassadors work to figure out ways to reduce the drug's cost, so 
consumers like me can afford it.

    Switching to new medication certainly had caused me some angst. I 
had no sense of how I will respond to the new infusion. Based on 
history, I've had my share of side effects during the 38 years I've 
been dealing with arthritis. I have trouble with drugs that are 
ingested through the GI tract. I also have had two different cancers, a 
risk accompanying many of the biologic arthritis medications. In 
addition, I've had some serious adverse reactions to medications, 
requiring hospitalization. Lucky for me, the new infusion, 100% covered 
by Medicare Part B, seems to be working well.

    Despite having this ailment, I consider myself to be healthy, doing 
whatever possible to maintain whatever I can do to stay well to 
overcome arthritis' swelling, fatigue, and pain that has challenged me 
physically and mentally. I probably have had more knee aspirations and 
steroid injections than some Olympic athletes. My Fitbit gets a daily 
workout. Even after trying many alternative treatments in search of a 
solution, Humira seemed to help me resume a normal life. And for that, 
I was grateful.

    AbbVie Chairman and CEO Richard A Gonzalez stated at the U.S. 
Senate Finance Committee on February 26, 2019, ``We believe it is 
important that discussions about access and affordability include a 
focus on how to alleviate Medicare Part D out-of-pocket burdens above 
and beyond just lowering list prices.'' I must raise the question to 
AbbVie: What is the company doing internally to cut costs for 
consumers?

    I am hoping that you will help address the mounting bureaucratic 
issues surrounding health care in America that make it challenging for 
consumers to afford and navigate. Please feel free to reach out to me 
if you need more information or assistance in any way.

    Yours,

Linda George

cc: Senator Patrick Toomey
  Senator Bob Casey
  Attorney General Josh Shapiro

                                 ______
                                 
                     Statement of Robin K. Huszagh
February 26, 2019

After listening to the hearing today on C-SPAN, I wanted to share my 
situation with you as a patient being forced to pay the full 
``negotiated'' price for Humira and Enbrel. My husband and I are self-
employed and self-insured. We must purchase health insurance through 
the independent ``retail'' market. I specifically renewed a 
grandfathered ``retail'' PPO health insurance policy we've had since 
2010 for our family of 3, now priced at $2,166.00/month, so that could 
get the specialty formulary I needed to treat my Rheumatoid Arthritis 
at an affordable price and continue to see my doctors. To my distress, 
the Insurer (BCBS) and Pharmacy Benefit Manager (Prime Therapeutics) 
altered the PPO plan's pharmacy benefits (cost sharing details) after 
the plan commenced, leaving me with an expensive policy that no longer 
covers my expensive specialty formulary at an affordable price. Unlike 
typical commercial employer-based group policies, once I needed the 
expensive specialty formulary, my independent retail PPO policy was 
switched into a restricted pharmacy network with only one mail-order 
supplier and an ``Accumulator Adjustment Program.'' The Insurer/PBM 
also blocked the use of drug manufacturer's discount coupons and 
programs completely (worth $12,000 to $16,000 per year in my case) so 
that a drug that used to cost me $5.00 to $10.00 per month with a 
manufacturer's coupon now costs between $5356 to $6652 per month, the 
negotiated contract rate between the insurer and the drug manufacturer. 
My deductible was raised from $2600 to $5200 for a 20% coinsurance 
responsibility and $11,200 out-of-pocket max for full benefits. The 
insurer added a second review process in 2019 for any drug with a 
contract rate of $5000/month or higher, in addition to the one put in 
place in 2018 as part of a ``step therapy'' restriction/review. In 2019 
the price for both Humira and Enbrel jumped to over $5000 per month and 
the insurer has stated their ``secondary review'' would allow them to 
deny benefits for these drugs even though the policy states they are 
approved formularies.

At the current premium rate, paying for insurance and an expensive 
formulary has been financially challenging to say the least and has 
caused us to take an early withdrawal from our IRA. I contacted the 
Illinois Department of Insurance and asked why insurers can change 
pharmacy benefits mid-year and weren't required to document the 
specific cost-sharing and pharmacy details on all insurance policy 
documents, so benefits are locked in for the year. I was told those 
details are NOT a requirement for retail plans, and pharmacy benefit 
changes are allowed to occur throughout the life of the contract which 
also includes medication price changes. So, if a consumer buys a policy 
based on access and pricing for a particular drug, there is no 
guarantee the terms will remain in effect for the full contract year. I 
was never notified of the changes even after contacting the insurer. I 
hadn't realized any changes until I went to the pharmacy to pick up a 
prescription and hit the payment ``brick wall''!

The Network Transparency Act of 2019 was passed in Illinois, however 
that only set policy guidelines for ``notification requirements'' to 
the policy holder if a particular provider pulls out of a network but 
doesn't address the insurer's ability to change a policy's pharmacy 
benefits mid-year, leaving the policy holder with a shocking bill. The 
contract price for Humira went up 9% in January, the cost of my PPO 
policy went up 9% in 2019, and now I'm required to pay a higher 
premium, higher out-of-pocket max, and the full price for Humira 
without the use of manufacturer's discount programs. Patients with 
employer-based group plans who are already benefiting from employer 
cost-sharing perks are allowed the use of discount programs and coupons 
at the point of sale (the pharmacy) because the insurer and the 
employer never know the coupon is being used as a form of payment at 
the retail pharmacy location. The coupon value pays for the drug and 
that hidden payment is applied to the user's deductible. Those who 
benefit from these programs do not care what the list price or the 
negotiated price is for a high-priced drug because they never have to 
actually pay it, the insurer pays for it because deductibles and out-
of-pocket limits are met early in the year. Those with commercial group 
plans obtain specialty formularies for $5 to $10 per month. I have to 
pay the full price. The change in my PPO policy was intentionally made 
by the insurer to ensure I personally pay the full cost of the drug for 
as long as possible. They do not want me to get assistance from Pharma 
to reach my deductible or maximum. There is no relief in sight for the 
independently insured who have no employer or government subsidies and 
actually pay the full high price for each medication and monthly 
insurance premiums. With the majority of Americans getting health 
insurance perks from their employer and using drug coupons, there is no 
incentive for drug manufacturers to ever lower list prices.

                                 ______
                                 
          Interfaith Center on Corporate Responsibility (ICCR)

                    475 Riverside Drive, Suite 1842

                           New York, NY 10115

                             (212) 870-2295

                              www.iccr.org

March 12, 2019

Mr. Chairman, Ranking Member and Members of the Committee:

ICCR is a coalition of over 300 global institutional investors 
representing more than $400 billion in managed assets. Leveraging our 
equity ownership in some of the world's largest and most powerful 
companies, ICCR members regularly engage management to identify and 
mitigate social and environmental risks resulting from corporate 
operations and policies. While ICCR members never shy away from making 
the moral case for action, our fundamental proposition as investors is 
that responsible and sustainable business practices--and a strong 
corporate culture of ethics--are in the long-term interest of 
companies, investors and communities.

ICCR members have a long-standing history of engagement with 
pharmaceutical companies on issues of price restraint, equitable 
pricing strategies, anti-competitive practices, marketing policies and 
practice, as well as disclosure of R&D expenditures (e.g., report on 
the number of products in the R&D pipeline that are new versus enhanced 
versions of existing products) and lobbying/political activities with 
agendas that may restrict the access and affordability of medicines.

For decades, ICCR members have pressed drug companies for greater 
disclosures on pricing structures as a way to promote greater access to 
medicines. A lack of transparency around how drug prices are determined 
has led to an industry-wide ethos of ``whatever the market will bear,'' 
which can lead to predatory pricing. We have asked companies to 
disclose the rates of price increases year-to-year of their top selling 
branded prescriptions drugs and to disclose the rationale and criteria 
used for these price increases. We have also asked the companies to 
assess the legislative, reputational and financial risks these 
increases represent for the companies. However, that lack of 
transparency still prevails.

Most recently, we have become increasingly concerned about 
pharmaceutical companies' governance structures and their Boards' 
ability to proactively mitigate risk related to high drug prices. A 
2017 Credit Suisse analyst report stated that ``US drug price rises 
contributed 100% of industry EPS growth in 2016'' and characterized 
that fact as ``the most important issue for a Pharma investor today.'' 
In response to this, in 2018 ICCR members filed resolutions at the 
companies highlighted in the 2017 Credit Suisse report asking ``the 
Compensation Committee (the `Committee') to report annually to 
shareholders on the extent to which risks related to public concern 
over drug pricing strategies are integrated into [company's] incentive 
compensation policies, plans and programs (`arrangements') for senior 
executives. The report should include, but need not be limited to, 
discussion of whether (i) incentive compensation arrangements reward, 
or not penalize, senior executives for adopting pricing strategies, or 
making and honoring commitments about pricing, that incorporate public 
concern regarding prescription drug prices; and (ii) such concern is 
taken into account when setting financial targets for incentive 
compensation arrangements.'' In other words, are executives 
incentivized to simply increase the price of drugs with no added 
benefit in clinical efficacy simply to meet short-term revenue targets?

In particular, we are seeking better articulation of the goal-setting 
process and the translation of those goals into incentive pay targets. 
We would strongly encourage you, as members of the Senate Finance 
Committee, to also seek written answers to the following questions:

      How assumptions about price changes are incorporated when 
revenue goals are set;
      Whether any policy or guideline exists regarding the preferred 
proportion of revenue growth derived from price increases;
      Whether any policy exists regarding unplanned price increases 
that would enable revenue goals or compensation revenue targets to be 
met and whether the board has to approve such increases; and
      How the compensation committee uses revenue goals or estimates 
to produce the various target levels (e.g., minimum, target and 
maximum) used to determine incentive payouts.

Mirroring Senator Wyden's concern that AbbVie's CEO's bonus is directly 
tied to the sales of Humira, we have also been asking why Humira sales 
are an appropriate measure for AbbVie's short-term incentive plan 
(STIP), and whether the company considers pricing increases when 
awarding STIP? AbbVie uses net revenue, income before taxes and Humira 
sales as metrics for the annual bonus and earnings per share (EPS) as a 
metric for certain long-term incentive awards to senior executives. For 
Pfizer, it is concerning to investors that the company publicly states 
that ``innovation in medicine has been and continues to be the 
cornerstone of the company,'' yet no pipeline metrics are included in 
the executive incentive agreements.

In addition to increased disclosure on incentive structures, we have 
also asked companies to formalize board oversight of prescription drug 
pricing risk. For example, what is Pfizer's board oversight of drug 
pricing, or lack thereof, which may have led to the settlement of the 
co-pay kickback investigation and drug shortages due to manufacturing 
or market issues. A 2018 Credit Suisse report highlighted AbbVie as 
among the companies most at risk from specialty pricing pressures in 
commercial insurance. Humira, which accounted for 65% of AbbVie's 
revenues in 2017 now faces competition in Europe from biosimilars, 
which are expected to cost less. Therefore, robust board oversight of 
risks related to drug pricing would provide a valuable outside 
perspective and help ensure that those risks are being managed for the 
long term.

Lastly, we also recognize that the strategy to expand monopolies 
without any meaningful new science is an unsustainable business model 
that exacts a heavy cost on patients and on the systems in which they 
seek care, and therefore, encourage companies to refrain from engaging 
in anti-competitive practices.

As investors, we want the companies in which we invest to be successful 
in the long term, with sustainable business models that deliver value 
to customers and stakeholders. Because pharmaceutical companies derive 
their social license to operate from their contribution to public 
health, it is critical that their businesses--including their executive 
incentives structures--reinforce, not undermine, that social contract. 
After many years of investor engagement in an effort to promote greater 
access and affordability of medicines, today we seriously question the 
value pharmaceutical companies are delivering to their shareholders and 
to the greater public.

If you have any questions, please contact, Meg Jones-Monteiro, Program 
Director--Health Equity, at [email protected] or (212) 870-2984.

             APPENDIX: 2019 ICCR EXECUTIVE INCENTIVES AND 
                     DRUG PRICING RISK RESOLUTIONS

2018 Companies: AbbVie, Amgen, Biogen, Bristol-Meyers Squibb, Eli Lilly
2019 Companies: AbbVie, Biogen, Bristol-Meyers Squibb, Celgene, Johnson 
& Johnson, Merck & Co, Pfizer, Vertex

Example 2019 Resolutions:

AbbVie (ABBV)

_______________________________________________________________________


RESOLVED, that shareholders of AbbVie Inc. (``AbbVie'') urge the 
Compensation Committee (the ``Committee'') to report annually to 
shareholders on the extent to which risks related to public concern 
over drug pricing strategies are integrated into AbbVie's incentive 
compensation policies, plans and programs (together, ``arrangements'') 
for senior executives. The report should include, but need not be 
limited to, discussion of whether (i) incentive compensation 
arrangements reward, or not penalize, senior executives for adopting 
pricing strategies, or making and honoring commitments about pricing, 
that incorporate public concern regarding the level or rate of increase 
in prescription drug prices; and (ii) such concern is considered when 
setting financial targets for incentive compensation arrangements.

Supporting Statement: As long-term investors, we believe that senior 
executive incentive compensation arrangements should reward the 
creation of sustainable long-term value. To that end, it is important 
that those arrangements align with company strategy and encourage 
responsible risk management.

A key risk facing pharmaceutical companies is potential backlash 
against high drug prices. Societal anger over exorbitant prices and 
pressure over limited patients' access due to unaffordability may force 
price rollbacks and harm corporate reputation.

We applaud AbbVie for committing not to increase prices by more than 
10% for 2018, yet we are unaware of a like commitment for 2019 or 
beyond. Moreover, we are concerned that the incentive compensation 
arrangements applicable to AbbVie's senior executives may undermine any 
such commitment.

AbbVie uses net revenue, income before taxes and Humira sales as 
metrics for the annual bonus and earnings per share (EPS) as a metric 
for certain long-term incentive awards to senior executives (2018 Proxy 
Statement, at 31). A 2017 Credit Suisse analyst report stated that ``US 
drug price rises contributed 100% of industry EPS growth in 2016'' and 
characterized that fact as ``the most important issue for a Pharma 
investor today.'' The report identified AbbVie as a company where price 
increases accounted for at least 100% of EPS growth in 2016 (Global 
Pharma and Biotech Sector Review: Exploring Future US Pricing Pressure, 
Apr. 18, 2017, at 1). It has been noted that the company's 2018 9.7% 
price increase for Humira could add $1.2 billion to the U.S. healthcare 
system (https://www.fiercepharma.com/pharma/drug-price-hikes-a-few-bad-
actors-or-widespread-pharma?mkt_tok=eyJpljoiWWpZeFlt
RTBOMIZoTkRJNSlslnQiOiJhckk2UONqNXBxNOx2UCtvdVdldzZVZXRIUHIrSOx
ZOVRBNXdTV1FOeVNBSDMxb3NWUGJsRWtNcFROZmlPYmM5d2hXd3VuVOkld
GICelBTYmk2).

In our view, excessive dependence on drug price increases is a risky 
and unsustainable strategy, especially when price hikes drive large 
senior executive payouts. We believe that the company's strategy to use 
``nursing support,'' which the California Department of Insurance 
claims in its suit against the company to be largely a kickback scheme 
to boost Humira sales, may have been better managed by leadership if 
Humira sales were not an explicit part of the payment incentive plan 
(https://www.law360.com/articles/1084008).

The disclosure we request would allow shareholders to better assess the 
extent to which compensation arrangements encourage senior executives 
to responsibly manage risks relating to drug pricing and contribute to 
long-term value creation. We urge shareholders to vote for this 
Proposal.

Merck & Co. (MRK)

_______________________________________________________________________

RESOLVED, that shareholders of Merck & Co., Inc. (``Merck'') urge the 
Compensation and Benefits Committee to report annually to shareholders 
on the extent to which risks related to public concern over drug 
pricing strategies are integrated into Merck's incentive compensation 
policies, plans and programs (``arrangements'') for senior executives. 
The report should include, but need not be limited to, discussion of 
whether (i) incentive compensation arrangements reward, or not 
penalize, senior executives for adopting pricing strategies, or making 
and honoring commitments about pricing, that incorporate public concern 
regarding prescription drug prices; and (ii) such concern is considered 
when setting financial targets for incentive compensation arrangements.

Supporting Statement: As long-term investors, we believe that senior 
executive incentive compensation arrangements should reward the 
creation of sustainable value. To that end, it is important that those 
arrangements align with company strategy and encourage responsible risk 
management.

We are concerned that the incentive compensation arrangements 
applicable to Merck's senior executives may discourage them from taking 
actions that result in lower short-term financial performance even when 
those actions may be in Merck's best long-term interests. Merck has 
committed to limit average price increases of its drugs to no more than 
the rate of inflation (https://www.marketwatch.com/story/merck-to-
lower-price-of-hep-c-treatment-zepatier-by-60-commits-to-responsible-
pricing-2018-07-19), but incentive compensation arrangements may be 
inconsistent with that commitment.

Merck uses revenue and pre-tax income as metrics for the annual bonus, 
and earnings per share (EPS) is a metric for performance share units 
granted after January 1, 2017 (2018 Proxy Statement, at 51, 61). A 2017 
Credit Suisse analyst report identified Merck as a company where U.S. 
net price increases accounted for at least 100% of 2016 net income 
growth (Global Pharma and Biotech Sector Review: Exploring Future US 
Pricing Pressure, Apr. 18, 2017, at 22).

In our view, risks to long-term value arise when large senior executive 
payouts can be driven by price hikes. Attention may focus on both high 
senior executive payouts and drug pricing, fueling public outrage. Ovid 
Therapeutics CEO Jeremy Levin has argued that incentives to boost 
short-term performance, such as EPS, lead executives to raise prices 
(and rebates to middlemen), starve research and development and buy 
back shares (https://www.biocentury.com/biocentury/strategy/2016-09-19/
why-jeremy-levin-says-executive-compensation-and-drug-pricing-must-).

Incentives may have societal implications, as one critic of high pay 
for healthcare executives has noted: ``[I]f the most influential 
executives of these companies are being paid to keep that [cost] 
trajectory up, that's money that's being taken away from education or 
infrastructure or other parts of the economy that may not be growing as 
quickly, and maybe that we'd want to grow more quickly'' (https://
www.npr.org/sections/health-shots/2017/07/26/539518682/as-cost-of-u-s-
heaIth-care-skyrockets-so-does-pay-of-heaIth-care-ceos).

The disclosure we request would allow shareholders to better assess the 
extent to which compensation arrangements encourage senior executives 
to responsibly manage risks relating to drug pricing and contribute to 
long-term value creation. For example, it would be useful for investors 
to know whether incentive compensation target amounts reflect 
consideration of pricing pressures. We urge shareholders to vote for 
this Proposal.

Pfizer (PFE)

_______________________________________________________________________

RESOLVED, that shareholders of Pfizer Inc. (``Pfizer'') urge the 
Compensation Committee (the ``Committee'') to report annually to 
shareholders on the extent to which risks related to public concern 
over drug pricing strategies are integrated into Pfizer's incentive 
compensation policies, plans and programs (``arrangements'') for senior 
executives. The report should include, but need not be limited to, 
discussion of whether (i) incentive compensation arrangements reward, 
or not penalize, senior executives for adopting pricing strategies, or 
making and honoring commitments about pricing, that incorporate public 
concern regarding prescription drug prices; and (ii) such concern is 
considered when setting financial targets for incentive compensation 
arrangements.

Supporting Statement: As long-term investors, we believe that senior 
executive incentive compensation arrangements should reward the 
creation of sustainable value. To that end, it is important that those 
arrangements align with company strategy and encourage responsible risk 
management.

A key risk facing pharmaceutical companies is potential backlash 
against high drug prices. Pfizer has been criticized for repeated price 
increases, and in July 2018 President Trump called out ``Pfizer and 
others'' in a tweet, saying they ``should be ashamed that they have 
raised drug prices for no reason''; Pfizer then postponed planned 
increases.

We are concerned that the incentive compensation arrangements 
applicable to Pfizer's senior executives may discourage them from 
taking actions, like foregoing price increases that result in lower 
short-term financial performance even when those actions may be in 
Pfizer's best long-term interests.

Pfizer uses revenue and earnings per share (EPS) as metrics for the 
annual bonus and operating income as a metric for performance share 
awards (2018 Proxy Statement, at 66, 68). A 2017 Credit Suisse analyst 
report identified Pfizer as a company where U.S. net price increases 
accounted for at least 100% of 2016 net income growth (Global Pharma 
and Biotech Sector Review: Exploring Future US Pricing Pressure, Apr. 
18, 2017, at 22). In its 2018 report, Credit Suisse characterized 
Pfizer's 2017 10% net price increase as above average for the industry 
and noted that its list price increases were the second highest (Global 
Pharmaceuticals: Scoring Sensitivity to Trump's Reforms, May 25, 2018, 
at 15, 20).

In our view, excessive dependence on drug price increases is a risky 
and unsustainable strategy, especially when price hikes appear to drive 
large senior executive payouts. Highlighting this connection, a March 
2018 article carried the headline, ``Pfizer CEO Gets 61% Pay Raise--to 
$27.9 Million--As Drug Prices Continue to Climb'' (https://
arstechnica.com/science/2018/03/amid-drug-price-increases-pfizer-ceo-
gets-61-pay-raise-to-27-9-million/; see also https://www.usnews.com/
opinion/articles/2017-08-30/bernie-sanders-take-on-big-pharma-and-
lower-prescription-drug-prices). We are concerned that large payouts 
based on financial metrics that can be affected by pricing create risks 
for Pfizer.

The disclosure we request would allow shareholders to better assess the 
extent to which compensation arrangements encourage senior executives 
to responsibly manage risks relating to drug pricing and contribute to 
long-term value creation. For example, it would be useful for investors 
to know whether incentive compensation target amounts reflect 
consideration of pricing pressures. We urge shareholders to vote for 
this Proposal.

                                 ______
                                 
          National Association of Free and Charitable Clinics

                      1800 Diagonal Road, Suite 600

                          Alexandria, VA 22314

        Nicole Lamoureux, President and Chief Executive Officer 

Chairman Grassley, Ranking Member Wyden and Members of the Committee, 
my name is Nicole Lamoureux and I am the President and Chief Executive 
Officer of the National Association of Free and Charitable Clinics. 
Last month, I was sitting in the hearing room as the pharma executives 
testified. While I applaud Congress for finally getting these 
executives to speak, I noticed some important gaps in the conversation.

During the hearing, both Congress and the pharmaceutical executives 
focused on a specific group of Americans: those with health insurance. 
Senate Finance Committee Chairman Grassley opened the hearing by 
describing how high list prices hurt ``those with high deductibles'' 
and ``taxpayers,'' but did not mention the uninsured. While we 
understand that the committee's focus remains largely on health 
programs within your jurisdiction that require significant federal 
investments, we believe that by not addressing the high cost of 
medication for the uninsured as well as the insured, the overall cost 
of health care will continue to increase.

When medication costs are too high, uninsured individuals must forgo 
their medication or split doses, and often end up needing the emergency 
department for both the repercussions of missed prescriptions and for 
primary care. Research shows that 75 percent of all emergency 
department visits not resulting in admission are for non-emergencies 
that should be treated outside of the emergency room (Hwang et al. 
2012). Patients who lack insurance and access to primary care are often 
forced to use the emergency room for routine medical needs. These 
emergency room visits are expensive, contribute to overcrowding, and 
drive up healthcare costs for everyone.

Currently, there are 27 million Americans without insurance--about 1 in 
12 people--and that number is growing. I know this group well. These 
are the people who receive access to health care and medication from 
the 1,400 free and charitable clinics in our country. Free and 
Charitable Clinics are safety-net health care organizations that 
utilize a volunteer/staff model to provide a range of medical, dental, 
pharmacy, vision and/or behavioral health services to economically 
disadvantaged individuals. Such clinics are 501(c)(3) tax-exempt 
organizations or operate as a program component or affiliate of a 
501(c)(3) organization. Free or Charitable Clinics restrict eligibility 
for their services to individuals who are uninsured, underinsured and/
or have limited or no access to primary, specialty or prescription 
health care. Additionally, Free and Charitable Clinics receive little 
to no state funding and no federal funding, do not receive HRSA 330 
funds, and are not Federally Qualified Health Centers or Rural Health 
Centers. Therefore, these clinics rely heavily on the generosity of 
individual donors, foundations and grants as funding sources.

Even though our organizations do not receive federal funding, we are 
impacted by every decision that is made at the federal level, 
especially when it comes to medication affordability. In 2018, the 
1,400 free and charitable clinics served 2 million Americans, with a 
total of 6.3 million patient visits. In the most recent data reported 
by our members, the number one concern for both our patient population 
and their providers is the high cost of medication.

I understand why Medicaid and Medicare patients were the main focus of 
the testimony, but the needs of millions of uninsured Americans are 
also critical to the conversation about solving the pricing issues and 
inequities of the current healthcare system. When Congress asked the 
seven executives, ``Who pays list price?'' Merck CEO Ken Frazier 
responded by saying, ``There's a small percentage of people who have no 
insurance who could actually be charged the list price.'' He also said 
that in our current system, ``The poorest and the sickest are 
subsidizing others.'' Senator Daines summarized the issue this way: "So 
the people who can afford it the least, arguably, are paying the list 
price?''

Those who are paying the list price are our patients, the uninsured and 
underinsured in this country. The current minimum price of $150 for a 
vial of insulin is not affordable for a mother making the choice 
between putting food on her table or paying for her prescription. Our 
patients have no choice but to ration medications, taking lower doses 
of them or stopping them altogether. We have no shortage of these 
stories, from young adults eating less than they should to reduce the 
amount of insulin they need to parents starving themselves to afford 
insulin for their children. In our network of clinics, this is a lived 
reality.

In a time when few issues are truly bipartisan, and health care 
continues to become ever more divisive, the exponential growth of drug 
prices is a rare issue that crosses the aisle. Needing insulin isn't 
red or blue, nor is using an EpiPen or depending on an inhaler to 
breathe. We need to harness this rare moment of unity and push for true 
progress.

I know that Congress realizes how important it is to have the 
conversation to make medication more affordable once and for all, so we 
can fix this broken system. I want to make sure we get it right this 
time around. America's free and charitable clinics try to catch the 
people who slip through the cracks. If we don't stop this unchecked 
rise in the cost of medications, these cracks will widen until they 
threaten the foundation of our health care system.

I appreciate the opportunity to submit my comments to the hearing 
record on behalf of the 2 million Americans who receive care at free 
and charitable clinics and look forward to answering any questions that 
the committee might have.

Works Cited:

Hwang, Liao, Griffin, and Foley. ``Do Free Clinics Reduce Unnecessary 
Emergency Department Visits?'' The Virginian Experience Journal of 
Health Care for the Poor and Underserved 23 (2012): 1189-1204.

                                 ______
                                 
                   National Business Group on Health

                       20 F Street, NW, Suite 200

                          Washington, DC 20001

                    202-558-3000  Fax 202-628-9244

                      www.businessgrouphealth.org

Chairman Grassley, Ranking Member Wyden and members of the Senate 
Committee on Finance, thank you for the opportunity to submit a 
statement for the record on the large employers' perspective on drug 
pricing.

The National Business Group on Health (NBGH or the ``Business Group''), 
whose members include 437 of the nation's largest employers, commend 
the Committee's effort to take a holistic look at the root causes of 
high and escalating drug prices. In addition to these, we anticipate 
submitting comments on subsequent hearings within the Committee's 
series on drug pricing.

Along with the government, taxpayers and families, employers have a 
vested interest in improving the efficiency and effectiveness of health 
care delivery, which includes the delivery of pharmaceuticals. 
According to NBGH's 2019 Large Employers' Health Care Strategy and Plan 
Design Survey, almost half, 49% of respondents are taking an activist 
role in driving delivery system change.\1\ As part of this, more 
employers are scrutinizing the role of the pharmaceutical supply chain, 
as specialty pharmacy costs remain one of the top drivers of overall 
health care trend. Particularly as the growth of high-deductible plans 
over the past decade has put a spotlight on drug prices, employers have 
become increasingly frustrated by complexity within the supply chain, 
which could be described as a ``rebate-driven'' contracting model.
---------------------------------------------------------------------------
    \1\ 2019 Large Employers' Health Care Strategy and Plan Design 
Survey, National Business Group on Health.

Nearly all employers believe the pharmaceutical supply chain model 
needs to change:
      14% believe it needs to be more transparent.
      35% believe rebates need to be reduced.
      49% believe the model needs to be overhauled and simplified.

Regarding the use of rebates as a mechanism to control drug costs:
      75% do not believe drug manufacturer rebates are an effective 
tool for helping to drive down pharmaceutical costs.
      91% would welcome an alternative to the rebate-driven approach 
to managing drug costs.

The rapid pace at which reforms are being considered within the 
marketplace and by both legislative and regulatory bodies at the 
federal and state levels is encouraging. A focus of the hearing, the 
Administration's proposals to implement changes to how pharmaceutical 
reimbursement and contracting is administered within Medicare Part Band 
Part D illuminates the need and possibility that there are likely to be 
multiple solutions that improve upon the current model within the 
private and public sector. NBGH supports a model marked by 
transparency, and one that removes incentives to consistently increase 
prescription drug prices. However, we also urge cautious, thoughtful, 
and analytical approaches that comprehensively evaluate the impact to 
market dynamics for all supply chain stakeholders.

Below, we highlight NBGH's perspectives on two of the widely discussed 
proposals. Our full comments on the International Pricing Index (IPI) 
model can be found online. Additionally, we intend to provide full 
comments on the rebate proposal by the April 8th deadline.
International Pricing Index (IPI) Model \2\
---------------------------------------------------------------------------
    \2\ ``International Pricing Index (IPI) Model,'' Center for 
Medicare and Medicaid Innovation, accessed March 11, 2019.
---------------------------------------------------------------------------
      We must take a broad perspective to assure that public policy 
decisions contribute to overall cost control and quality improvement 
for all Americans. We commend the Administration's commitment to 
lowering the cost of prescription drugs and encourage it to seek 
solutions. However, we strongly recommend that whatever CMS adopts, 
part of the consideration and criteria for evaluating the results must 
be the impact on the private market and the 170 plus million people 
covered by employers and insurers and not limited to the impact on 
Medicare alone. If we as a nation are to succeed in controlling health 
care costs, we must ensure that public policy decisions do not merely 
``squeeze the cost balloon'' in one area only for it to expand and 
exacerbate the problem in another area.
      Our chief concern centers on the ANPRM's proposal to link 
reimbursement rates to other nations' prices. Apart from the fact that 
these nations determine prices differently, have different patent and 
exclusivity models, and often vastly different incentives for 
biosimilar utilization, we are concerned that the impact on prices for 
the same pharmaceuticals in the US may rise in the private sector and 
the market for biosimilars may be adversely impacted if Medicare adopts 
this approach.
Rebate Reform Proposal \3\
---------------------------------------------------------------------------
    \3\ ``Fraud and Abuse; Removal of Safe Harbor Protection for 
Rebates Involving Prescription Pharmaceuticals and Creation of New Safe 
Harbor Protection for Certain Point-of-Sale Reductions in Price on 
Prescription Pharmaceuticals and Certain Pharmacy Benefit Manager 
Service Fees'' (Federal Register, February 6, 2019).
---------------------------------------------------------------------------
Many large employers have already begun evaluating the utility of 
point-of-sale rebates as part of their benefit design and a subset (29 
percent) have them in place today. Thus, HHS's proposal picks up on the 
momentum from large employers and, more importantly, underscores the 
inefficiency of the pharmaceutical supply chain. Given the market 
momentum on this issue, to both lower out-of-pocket costs for patients 
and evaluate ways to simplify a complex system, the Business Group is 
in favor of market-based solutions relative to point-of-sale rebates. 
NBGH has the following serious concerns about proposals around rebates.

While the stated goal of these proposals is to lower prescription drug 
prices and out-of-pocket costs for consumers by encouraging PBMs to 
pass discounts from drug manufacturers directly on to consumers and 
bring transparency to prescription drug market, we have various 
concerns with the proposals including but not limited to the following:

      The proposals focus on out-of-pocket costs only. The intent of 
the proposed rule and companion legislation is to lower out-of-pocket 
costs at the pharmacy counter and add needed pricing transparency to 
the market. While we support the proposed increased transparency and 
pricing relief for patients, we urge policy makers to avoid ``quick 
fixes'' that focus only on out-of-pocket costs, as opposed to total 
cost to the system. Focusing on out-of-pocket costs only has the 
potential to mask root causes of price increases, potentially lead to 
even higher increases over time, and drive the escalating trend on drug 
expenditures.

      Any changes in supply-chain contracting should not result in a 
net increase in drug costs to any payor, nor windfall to any supply 
chain stakeholder. Medicaid and CHIP Payment and Access, the 
Congressional Budget Office Commission (MACPAC) staff have noted that 
the CMS Office of the Actuary (OACT) estimated a net increase in 
Medicaid drug spending of $200 million over 10 years if the proposed 
rebate rule is finalized. A large chunk, if not the largest chunk, of 
this expected increase would come from the decline in inflation-based 
rebates.\4\ Further, manufacturer claim liabilities through the 
coverage gap discount program (CGDP) would be lower, which would 
produce an overall substantial savings for 
manufacturers.\5\, \6\ While savings is expected, that 
savings should be realized comprehensively across both the supply and 
demand sides of the pharmaceutical supply chain.
---------------------------------------------------------------------------
    \4\ ``Proposed Safe Harbor Regulation Impact'' (Office of the 
Actuary, August 30, 2018).
    \5\ Manufacturer payments through the CGDP are expected to be about 
$2 billion per year lower on average. When POS costs are lower, it 
takes longer for he costs to accumulate toward the initial coverage 
limit (ICL) and the TrOOP threshold. CGDP payments would be lower as 
fewer members would be calculated as a percentage of a lower POS cost, 
but the impact would vary by manufacturer and by plan sponsor.
    \6\ ``Impact of Potential Changes to the Treatment of Manufacturer 
Rebates'' (Milliman, Inc., January 31, 2019).

      The proposals do nothing to address list prices. The proposed 
rule ``intends'' and speculates that manufacturers might lower list 
prices, but there is little assurance that manufacturers will offset 
rebates with price reductions. In fact, at the hearing, not all CEOs in 
attendance would affirmatively state this would be the case at all, due 
to antitrust case law.\7\
---------------------------------------------------------------------------
    \7\ ``Foley Hoag LLP white paper, ``Antitrust Implications of a 
Proposed HHS Rule to Limit Manufacturer Rebates,'' accessed March 11, 
2019.

      The proposed timeline within the HHS proposal is arguably too 
aggressive. PBMs have largely already concluded negotiations on price 
concessions for plan year 2020 and are in the middle of actuarial 
analysis to prepare bids. There is no way to renegotiate in time to 
know the associated costs in order to bid properly, and it would be 
---------------------------------------------------------------------------
impossible to retool the supply chain in such a short period of time.

      Premiums will increase. The proposals are projected to increase 
the cost of healthcare for those who don't use drugs having rebates, 
through premium increases, while disproportionately decreasing costs 
for those who do use drugs with discounts.

Thus, while we agree that the rebate-driven model is ripe for reform 
and ineffective at controlling drug prices, we are concerned about the 
unintended consequences associated with the proposals as written.

In addition to contracting concerns within the rebate-driven model, 
there remains substantial opportunity for policy change relative to 
prescription drug prices, most of which would encourage a more 
competitive and dynamic market with correspondingly more affordable 
prices.
Advance Policies to Promote More Affordable, Financially Sustainable 
        Prescription Drug Pricing
While many of the recommendations below are directed toward various 
agencies in the Administration, several of them require Congressional 
action. All of these policy recommendations are highlighted in the 
National Business Group on Health's Issue Brief on Policy 
Recommendations to Promote Sustainable, Affordable Pricing for 
Specialty Pharmaceuticals.

      Remove Uncertainties Surrounding Risk-based and Value-Oriented 
Contracting and Implement Indication Specific Pricing and Reference 
Pricing in Public Programs:
        -  Consider exemptions for value-based contracts from Medicaid 
best price requirements and clarify how drug makers and payers can 
conceive of value-based contracts without triggering broader Medicaid 
best price program implications.
        -  Allow for variable pricing, where the price better reflects 
the evidence for benefit.
        -  Evaluate the usefulness and application of the existing 
developed value frameworks and their potential to impact drug pricing 
in public programs, as well as their overall utility to the health care 
system.
        -  Directly link reimbursement and improved patient outcomes.
        -  Consider how drug makers and payers can enter into other 
types of innovative VBP arrangements, such as indication-specific 
pricing.
        -  Implement reference pricing policies supported by clinical 
evidence consistently across public programs, where possible.

      Limit Reach of Medicare Part D Protected Classes:
        -  Following the MedPAC's recommendations, the Congress and CMS 
should limit legislative and regulatory restrictions on formulary 
design within protected classes by modifying the Medicare Part D rules 
to remove those protected classes where enough generic competition 
exists, a change that would give private plans more freedom to control 
their formularies and negotiate for expanded manufacturer rebates.
        -  Specifically, CMS should resubmit its proposal to remove 
antidepressants, antipsychotics, and immunosuppressants for transplant 
rejection from the list of protected classes because, in these classes, 
price reductions have been more closely linked with the availability of 
generics than to their status as ``protected'' and stand firm against 
industry-funded campaigns that seek to undermine the agency's data-
driven proposal to increase competitive pricing.
        -  At a minimum, policy makers should evaluate the potential 
anticompetitive influence of protected classes on the commercial 
market, and specifically, evaluate the limitations imposed on private 
payers' ability to negotiate competitive prices for drugs in the 
protected classes due to market spillover.

      Eliminate Perverse Payment Incentives Under Medicare Part B:
        -  Eliminate financial incentives for prescribing more 
expensive medicines, in more expensive settings.
        -  Establish direct links between reimbursement and improved 
patient outcomes.
        -  Encourage manufacturers to assume some financial risk for 
use of high-priced drugs.

      Encourage the Uptake of Biosimilars:
        -  Consider the utility of having an ``interchangeability'' 
distinction and potential alignment with the European biosimilars 
model, which has no such distinction.
        -  Work with stakeholders to disseminate provider and patient 
education to firmly establish the safety and efficacy of biosimilar 
drugs to their reference products, recognizing that key successes to 
the uptake of biosimilar medicines in other countries was predicated on 
the creation of trust and confidence among all the stakeholders 
involved, such as prescribers, pharmacists, and patients.
        -  Maintain payer autonomy to implement utilization management 
tools for specialty pharmaceuticals, including tools that pertain to 
biosimilar products.

      Reform Permissive Patent and Exclusivity Protocols:
        -  Reduce the market exclusivity period for biologics from 12 
years to 7 years.
        -  Eliminate or limit additive patent extensions and 
exclusivity periods that serve only to extend monopoly power, 
especially where there is limited, or no additional company investment 
or patient value produced.
        -  Develop sound policy that would discourage patent abuses 
such as ``evergreening'' and ``product hopping.'' These policies may 
include financial penalties, loss of exclusivity periods and/or reduced 
patent terms for other products.
        -  Refine the biosimilars patent dance to effectively 
incentivize the use of the section 351(1) patent dispute resolution 
provisions.

      Reject anticompetitive ``quick fixes'':
        -  As consumers find themselves paying more of their drug 
costs, it's tempting to be lured into new policies which may only 
further contribute to an anticompetitive climate. These policies may 
include specialty drug price caps, out-of-pocket payment caps, 
limitations on utilization management tools and mandated disclosure of 
propriety information.
        -  Additionally, a federal law permitting importation 
nationwide could lead to some price reductions for both payors and 
patients in the short-term but, as markets adapt, it is unclear what 
the long-term effect on prices would be. It would also likely require a 
significant boost in resources for the Food and Drug Administration 
(FDA) to monitor imports and assure safety.

The National Business Group on Health, representing 437, primarily 
large, employers (including 70 of the Fortune 100) who voluntarily 
provide valued health benefits and other health programs to over 55 
million American employees, retirees, and their families, looks forward 
to working with you on our shared goals for health care: lower costs, 
improved access, and higher quality--umbrella goals we consider 
inclusive of prescription drugs. Please contact Steven Wojcik, the 
National Business Group on Health's Vice President of Public Policy, at 
(202) 558-3012, if you would like to discuss our comments in more 
detail or if we can provide additional information as the Committee 
continues its evaluation of drug pricing.

Sincerely,

Brian J. Marcotte
President and CEO

                                 ______
                                 
        National Coordinating Committee for Multiemployer Plans

                          815 16th Street, NW

                          Washington, DC 20006

                       Telephone: (202) 737-5315

                   Michael Scott, Executive Director

The National Coordinating Committee for Multiemployer Plans (the 
``NCCMP'') appreciates the opportunity to provide comments to the 
Committee on the issue of prescription drug pricing and the challenges 
that multiemployer group health plans face in today's environment. We 
also appreciate the efforts of the Committee to promote discussion of 
solutions to America's problem of the high cost of prescription 
medications.

Background on the Multiemployer Plans and the NCCMP

Multiemployer plans are a product of the collective bargaining process, 
where at least one labor organization and two or more employers provide 
health, pension and a variety of other employee benefits through 
negotiated contributions to trust funds that are required by law to be 
maintained for the ``sole and exclusive benefit'' of plan participants. 
Multiemployer plans are jointly trusted by both labor and management 
and are subject to applicable provisions of the Taft-Hartley Act, 
ERISA, and the Internal Revenue Code. The NCCMP is the only national 
organization devoted exclusively to protecting the interests of the 
over 20 million active and retired American workers and their families 
who rely on multiemployer plans for retirement, health, and other 
benefits. The NCCMP is a nonprofit, non-partisan organization with 
members, plans, and contributing employers in a broad range of 
industries, including agriculture, building and construction, bakery 
and confectionary, entertainment, health care, hospitality, longshore, 
maritime, mining, retail food, service, steel, and trucking. The 
NCCMP's purpose is to assure an environment in which multiemployer 
plans continue their vital role in providing benefits to working men 
and women.

Multiemployer health plans are often self-insured and plan sponsors 
contract with both medical and pharmacy benefit managers to provide 
administrative services. These plans provide benefits to both active 
workers and their families, and to retirees. Consequently, 
multiemployer plans will often contract with a Medicare Part D 
Prescription Drug Plan or Medicare Advantage plan to provide 
prescription drug and other benefits to retired participants.

Prescription Drug Prices Continue to Rise

Most multiemployer health plans provide prescription drug coverage to 
active employees, dependents, and retirees. Prescription drug costs are 
a significant part of health plan expenses. Multiemployer plan sponsors 
have looked to a variety of means to lower drug prices. Strategies 
include increased use of step therapy, prior authorization, quantity 
limits, formularies (which exclude certain drugs) and other utilization 
management techniques. However, prescription drug cost increases are 
primarily driven by price increases, not increased utilization.\1\ Drug 
price inflation is a significantly greater component of projected 
prescription drug price trend than utilization. In addition, specialty 
drug price increases are projected to be in the double digits for 2019, 
a significant and concerning pattern because specialty drugs now 
account for as much as 35 percent of total pharmacy spending.\2\ New 
specialty brand drugs to treat serious illnesses contribute to the cost 
increase, and there are limited opportunities to substitute generic 
drugs in therapeutic classes dominated by single-source specialty brand 
drugs. Consequently, plan sponsors cannot effectively control prices 
through utilization controls alone.
---------------------------------------------------------------------------
    \1\ 2019 Segal Health Plan Cost Trend Survey, available at http://
www2.segalco.com/me-trend-survey-20l9.pdf.
    \2\ Id.
---------------------------------------------------------------------------

Areas for Congressional and/or Regulatory Inquiry and Action

The NCCMP recommends that the Committee take action to promote 
transparency in the rebate system while ensuring that action taken on 
the rebate side of the pricing equation results in lower--not higher--
drug prices paid by plan sponsors and consumers. In addition, we 
emphasize the NCCMP's commitment to eliminating the tax that penalizes 
plan sponsors and workers for the high costs of health care (including 
drug costs) beyond their control.
Rebates and Transparency
Rebates account for a substantial portion of the drug pricing equation. 
Rebate offsets that are passed through to multiemployer plan sponsors 
from pharmacy benefit managers (PBMs) help to lower net plan cost 
trends. However, multiemployer plans must aggressively monitor PBMs to 
assure that rebates are actually passed through to the plan, and in 
many cases, the rebate structure is opaque and impenetrable. Pricing 
structures also change frequently, as can be seen by some of the PBMs 
``market pricing'' strategies, which adjust prices, rebates, and 
participant cost sharing based on market price variations for certain 
drugs.

State legislators are increasingly attempting to rein in drug costs by 
passing laws requiring greater transparency. However, those laws may 
not be effective, either because the states cannot tackle the problem 
alone, or the laws will be subject to multiple challenges by 
pharmaceutical manufacturers and PBMs.

As a core principle of ERISA, employee benefit plan fiduciaries need 
information concerning all compensation to be received by a service 
provider and any conflicts of interest that may adversely affect the 
service provider's performance under the contract or arrangement. In 
2014, the NCCMP provided supporting testimony to the ERISA Advisory 
Council, which was studying PBM Compensation and Fee Disclosure.\3\ At 
that time, we suggested that plan fiduciaries would be well served if 
PBMs were required to disclose all instances in which they receive 
financial remuneration from drug manufacturers, retail pharmacy 
providers, and data managers. The disclosures need to be sufficient to 
allow trustees to assess whether, and to what extent, the services 
offered by the PBMs are in the best interest of plan participants, 
rather than simply furthering the financial interests of the PBM. 
Transparency continues to be a concern to plan sponsors and efforts of 
the Committee to increase transparency for rebates and financial 
arrangements between PBMs and pharmaceutical manufacturers would assist 
multiemployer plans in efforts to control prescription drug prices.
---------------------------------------------------------------------------
    \3\ https://www.dol.gov/sites/default/files/ebsa/about-ebsa/about-
us/erisa-advisory-council/2014-pbm-compensation-and-fee-disclosure.pdf.

More attention is being paid of late to the rebate system and the 
important role that it plays in determining the prices that plan 
sponsors and consumers pay for prescription drugs. But rebates are only 
part of the equation. The list price that drug manufacturers set for 
their prescription drugs is the starting point for the negotiation 
between manufacturers and PBMs over rebates. More transparency in the 
setting of list prices could help to put some downward pressure on 
those prices. But if list prices continue to go up while rebates go 
down, plan sponsors and consumers will end up paying more. As a result, 
it is essential that any action taken to address the rebate structure 
not have the unintended consequence of actually increasing what plan 
sponsors and consumers pay for prescription drugs.
Eliminating the Unfair Tax on Health Plan Coverage
For decades before the enactment of the Patient Protection and 
Affordable Care Act (ACA), the majority of Americans with health 
coverage received their coverage through employment. This has remained 
the case well after the ACA first went into effect. Today, over 181 
million Americans have employment-based health coverage, which includes 
coverage under multiemployer plans. The 40 percent excise tax under 
Internal Revenue Code section 49801, enacted as part of the ACA, 
threatens these hard-working Americans with a steep and unfair tax on 
their health coverage. Sometimes popularly (although inappropriately) 
referred to as the ``Cadillac plan'' tax, the original intent of the 
tax was to impact plans with ``gold-plated coverage.'' In actuality, 
however, the tax will have a much broader impact on even modest plans 
as a result of underlying medical inflation.

Employers understand that quality health care is an investment in 
employees and not simply a monetary benefit. At the same time, both 
employers and employees recognize that the cost of health care cannot 
become so great that it makes employers non-competitive. This 
marketplace reality is the reason that the vast majority of private 
plan sponsors have utilized cost containment strategies for decades to 
manage and stretch finite compensation dollars as much as possible.

Unfortunately, the high and ever-increasing health care costs faced by 
the private sector are directly amplified by the U.S. Government 
through its own health care programs, statutes, and regulatory 
requirements. As the largest provider and purchaser of health care in 
the U.S. through Medicare and Medicaid, programs that collectively 
spend more than $1.2 trillion annually,\4\ the U.S. Government's 
longstanding policy of significantly under-compensating health care 
providers results in these providers charging more to their private 
sector clients in order to recoup their uncompensated federal expenses. 
In this way, the private sector subsidizes Medicare, Medicaid, and the 
U.S. Government by absorbing these uncompensated expenses through 
higher costs and premiums.
---------------------------------------------------------------------------
    \4\ In 2017, Medicare spending grew 4.2% to $705.9 billion in 2017 
and Medicaid spending grew 2.9% to $581.9; https://www.cms.gov/
research-statistics-data-and-systems/statistics-trends-and-reports/
nationalhealthexpenddata/nhe-fact-sheet.html.

The simple fact is that the high costs of employment-based health plans 
and medical inflation are not driven by employment based health plans 
themselves, but by other factors, including the actions (and inactions) 
of the U.S. Government. Congress should continue to work to address 
medical care inflation, including rising drug costs, while maintaining 
good health care outcomes and quality of care. Congress should not 
penalize employers, health plans, or employees and their families 
through unfair taxes. If the excise tax is imposed, the end result will 
not be an overall reduction in health care costs, lower medical 
inflation or higher federal tax revenue; rather it will be borne by 
hardworking Americans through cost-shifting and foregoing needed care. 
Additionally, as employment based healthcare is penalized, it will 
become increasingly unavailable to those currently covered, which will 
increase federal spending on subsidies and Medicare as a significant 
portion of the currently covered workforce is eligible for these 
---------------------------------------------------------------------------
programs.

NCCMP appreciates the actions Congress has taken in the past to help 
prevent the imposition of the 40 percent excise tax by delaying it 
twice, so that the effective date is now pushed back to 2022. Delays, 
however, are not sufficient to prevent the harmful impact of this tax. 
In calling for repeal, NCCMP joins the voices of a large, diverse 
group, as evidenced by a recent letter to Congress signed by over 550 
organizations representing such interests as public and private sector 
employers across a wide range of industries, non-profit organizations, 
chambers of commerce, unions, and patient groups. We support the bi-
partisan Middle Class Health Benefits Tax Repeal Act of 2019, recently 
introduced in the Senate by Senators Heinrich (D-NM) and Rounds (R-SD) 
and co-sponsored by many others, including members of this Committee. 
We also support the House version of the bill, which was introduced in 
January and which as of this writing has 229 co-sponsors, with growing 
numbers.

The NCCMP recommends fully and immediately repealing the 40% excise tax 
on employer sponsored health coverage and also opposes any efforts to 
tax employees on their health care benefits.

                                 ______
                                 
                             Oxfam America

                    1101 17th Street, NW, Suite 1300

                          Washington, DC 20036

  Tel +1 (202) 496-1180 | Fax +1 (202) 496-1190 | www.oxfamamerica.org

                           February 26, 2019

Mr. Chairman, Ranking Member and Members of the Committee,

Oxfam appreciates the Committee's sincere intention to ensure 
affordable and accessible medicines for all who need them. We would 
like to take this opportunity to bring the Committee's attention to our 
recent investigation, Prescription for Poverty,\1\ illustrating how 
four major pharmaceutical firms (three of whom are testifying before 
the Committee at this hearing) may well be underpaying their US taxes 
to the tune of $2.3 billion annually by systematically stashing their 
profits in overseas tax havens. On top of these tax losses from 
offshore tax avoidance, these companies likely benefitted significantly 
from the Tax Cuts and Jobs Act (TCJA).\2\
---------------------------------------------------------------------------
    \1\ Oxfam, ``Prescription for Poverty: Drug companies as tax 
dodgers, price gougers, and influence peddlers,'' Sept. 2018 at https:/
/www.oxfamamerica.org/explore/research-publications/prescription-for-
poverty/.
    \2\ Report of the Senate Finance Committee Democratic Staff, 
``Trump Tax Law and the Health Care Industry: A $100 Billion Bonanza,'' 
April 17, 2018.

Here in the US and around the world, in rich and poor countries alike, 
high drug prices are causing too many people to sacrifice their savings 
or worse--their lives--to enrich executives at highly profitable and 
---------------------------------------------------------------------------
influential drug companies.

As is well known, these drug companies' very business model depends to 
a large degree on American taxpayer dollars: to pay for essential 
front-end drug research, to protect patents and intellectual property, 
and to purchase their drugs through Medicare, and the Veteran's 
Administration.

Yet, these same companies are undermining public trust (and their very 
own business model) by steadily under-paying their taxes, in the US and 
around the world. Scouring the companies' financials, we've found that 
four major pharmaceutical firms--Abbott, Johnson & Johnson (JNJ), Merck 
(MRK), and Pfizer (PFE)--alone appear to have deprived rich and poor 
countries alike of around $3.7 billion of vital revenue that could have 
been spent on vaccines, midwives, or health clinics. Because the 
companies reveal little financial information about their subsidiaries, 
Oxfam's investigation barely scratches the surface. Yet even a small 
sampling reveals a striking degree of tax avoidance through profit-
shifting.

As the largest market for the four pharmaceutical companies, the United 
States is the biggest loser from tax avoidance by these companies, to 
the tune of an estimated $2.3 billion a year: $1 billion by JNJ, $589 
million by Pfizer, $533 million by Merck, and $143 million by Abbott. 
Together, this is enough to pay for health insurance for nearly a 
million low-income children in the US.

How are companies avoiding their tax responsibilities?

Oxfam examined publicly available data on subsidiaries of four of the 
largest US drug companies and found a striking pattern. In the 
countries analyzed with standard corporate tax rates, the companies 
reported low pre-tax profits--7 percent profits on average in high-
income countries, and 5 percent on average in seven low- and middle-
income countries. In contrast, these corporations reported annual 
global profits of up to 30 percent. So, where were these companies 
reporting such sky-high profits? Tax havens. In four countries which 
charge very low or no corporate tax rates, these companies posted 31 
percent profit margins--suggesting that the companies are artificially 
shifting their profits to avoid paying taxes in countries with higher 
tax rates.

In the case of the pharmaceutical giants, the ploy may involve 
``domiciling'' their patent, not in the corporation's home country 
where the drug was actually developed, but in a tax haven-where a 
company's presence may be as little as a mailbox. That subsidiary then 
charges hefty licensing fees to subsidiaries in other countries. The 
fees are a tax deductible expense in the normal jurisdictions, meaning 
that they can be used to offset any earnings and thereby lower the 
reported profits. At the same time, the fee income accrues to the 
subsidiary in the tax haven, where it is taxed lightly or not at all. 
The company's overall tax payment then is lowered, sometimes 
significantly.

Another technique many companies have used is to sell their production 
or services not directly to the countries where they will be consumed, 
but to ``pivot'' companies in low tax jurisdictions that then resell 
them at a profit to affiliated distributors. This practice creates an 
artificial profit that remains in the tax haven. Most of the time, 
these are only paper transactions--the goods are shipped straight from 
the factory in the production country to the warehouse in the 
consumption country--but the transactions allow profits to move from 
one country to another almost tax-free.

Because companies refuse to release their full country-by-country 
financial reports to the public, and many governments have yet to make 
these reports public, the information on tax dodging is far from 
complete. Yet, the pattern of Big Pharma's tax practices is consistent: 
this is either an astounding coincidence or the result of using 
accounting tricks to deliberately shift profits from where they are 
actually earned to tax havens. Pfizer, Merck, and Abbott are among the 
20 US corporations with the greatest number of subsidiaries in tax 
havens; Johnson & Johnson is not far behind. While profits can vary 
from country to country for any number of legitimate reasons, it is 
highly unlikely that these explanations can fully account for the 
consistent pattern of much higher profits being posted in countries 
with very low tax rates where these corporations do not sell the 
majority of their medicines.

Tax injustice and price gouging are two sides of the same coin

Tax avoidance and price gouging are not, in fact, completely 
independent phenomena. Today's hearing provides a timely opportunity to 
connect the dots between high drug prices and unjust tax avoidance 
practices which deprive the US Treasury of precious public revenue 
needed to fund essential public health programs in the US. Every tax 
dollar avoided means a tax dollar less for new drug research at the 
National Institutes of Health, and for essential health insurance 
programs like Medicaid, Medicare and the Child's Health Insurance 
Program.

What's more, as we detail in our report cited above, a cornerstone of 
these companies' business model--the intellectual property rules 
protecting many of these pharmaceutical companies' most profitable 
products--is a central factor in allowing these companies to drive up 
drug prices, while driving down their tax payments. And conversely, our 
tax system at present incentivizes price hikes in a variety of ways.

While the specific solutions to drug pricing and tax avoidance are 
distinct, there are some essential common approaches in our view. 
Global companies should be transparent about where they earn and spend 
their money, they should pay tax in alignment with actual economic 
activity rather than abuse our tax system in a variety of ways, and 
they should use their political influence responsibly, rather than 
undermining governments' efforts to provide essential medicines and 
healthcare for us all.

------------------------------------------------------------------------
 
-------------------------------------------------------------------------
In this context, we would encourage the Senate Committee to raise the
 following questions to JNJ, PFE and MRK during the February 26th
 hearing:
 
1. According to evidence received, your companies systematically report
 low pre-tax profits in high-tax countries, and high pre-tax profits in
 low-tax countries: reportedly resulting in billions of dollars of lost
 revenue in the US which could have been spent on new drug research or
 to fund essential healthcare. Can you explain why these aggressive tax
 planning practices serve the public interest?
 
2. Is your company involved in offshore tax avoidance? If so, please
 explain why you believe this is acceptable practice. Can you commit to
 publicly releasing your company's country-by-country financial reports
 to show and prove your tax practices meet social expectations?
 
3. How has your company invested the fresh cash resulting from the
 passage of the TCJA? Very concretely, can you explain how these
 expenditures are working to drive down drug prices? If they are not
 doing so, why not?
------------------------------------------------------------------------

For any questions, please contact Nicholas J. Lusiani, Senior Advisor 
at [email protected], or (202) 777-2912.

                                 ______
                                 
                   Patients for Affordable Drugs Now

                  Statement by David Mitchell, Founder

Chairman Grassley, Ranking Member Wyden, and members of the Senate 
Finance Committee,

Thank you for your leadership to address the problem of high drug 
prices in America. U.S. patients and taxpayers spend more than $450 
billion \1\ each year on prescription drugs. By some estimates, nearly 
one-fifth \2\ of all health care costs go toward prescription drugs. 
The main driver of prescription drug spending is patent-protected 
brand-name drugs, which make up only about 10 percent \3\ of 
prescriptions but account for three-quarters of drug spending.\4\
---------------------------------------------------------------------------
    \1\ https://www.finance.senate.gov/imo/media/doc/
29JAN2019MILLERSTMNT.pdf
    \2\ https://www.ncbi.nlm.nih.gov/pubmed/27552619.
    \3\ https://docs.house.gov/meetings/GO/G000/20190129/108817/HHRG-
116-GOOO-Wstate-KesselheimA-20190129.pdf.
    \4\ https://docs.house.gov/meetings/GO/G000/20190129/108817/HHRG-
116-GOOO-Wstate-KesselheimA-20190129.pdf.

That's why today's hearing is so important. You have called CEOs of 
seven major drug corporations before the Senate Finance Committee to 
explain their pricing practices, patent thickets and the fact that 
American patients and taxpayers pay anywhere from two to six times \5\ 
more than the rest of the world for brand name prescription drugs.
---------------------------------------------------------------------------
    \5\ https://www.cnn.com/2015/09/28/health/us-pays-more-for-drugs/
index.html.

We hear every day from patients suffering under the high cost of 
prescription drugs--cutting pills in half, choosing between groceries 
---------------------------------------------------------------------------
and medication, and simply going without.

Patients have questions for the CEOs in front of you today, and we hope 
Congress will ask them.

AbbVie Inc,

About AbbVie: AbbVie's anti-inflammatory drug Humira is the top-selling 
\6\ drug in the world. The drug company doubled the price \7\ from 
about $19,000 per year in 2012 to $38,000 per year in 2018. AbbVie 
secured over 100 patents \8\ on Humira, ensuring that patent thickets 
will keep competition off the U.S. market, while the company cut the 
price in Europe by 80 percent \9\ for the exact same drug.
---------------------------------------------------------------------------
    \6\ https://www.nytimes.com/2018/01/06/business/humira-drug-
prices.html.
    \7\ https://www.nytimes.com/2018/01/06/business/humira-drug-
prices.html.
    \8\ https://www.bloomberg.com/news/articles/2017-09-07/this-shield-
of-patents-protects-the-world-s-best-selling-drug.
    \9\ https://www.axios.com/abbvie-cuts-humira-price-europe-
biosimilars-cc2d3d61-5782-4042-8c24-b322ea8285b4.html.

Questions:
      Is it fair that Europeans have access to a less expensive 
biosimilar competitor for Humira, but your company bragged \10\ about 
blocking that competition in the U.S.?
---------------------------------------------------------------------------
    \10\ https://www.nbcnews.com/nightly-news/video/world-s-best-
selling-drug-costs-five-times-more-in-u-s-than-europe-1445064259924.
---------------------------------------------------------------------------
      Do you partake in pay for delay or deals for delay? Do you 
support the Preserve Access to Affordable Generics and Biosimilars Act 
(S. 64)?
      Since Humira has already been very successful with more sales 
than the revenue of eBay,\11\ will you commit to holding the price of 
Humira steady until a biosimilar comes to market?
---------------------------------------------------------------------------
    \11\ https://www.axios.com/humira-2018-revenues-drug-prices-
eb637e1f-09ae-479a-91ca-870edf7f5b4a.htm.

Patient Stories:
      James Baer from Aurora, CO: ``I have seropositive degenerative 
rheumatoid arthritis, and am on a regimen of high cost drugs. Humira is 
the most expensive, at $4,500-$6,500 a month. My insurance, Humana, is 
refusing to pay for it starting next month. My doctor says I need it to 
win my fight against this genetic defect.''
      Jacquie from Iowa: ``Since my Crohn's diagnosis, I've taken 
Lialda and Humira. Both drugs would have been astronomical if I hadn't 
been for my good insurance and eligibility for the pharmacy savings 
programs for each. I have been lucky. But I am always constantly 
worried about no longer being able to work due to my health, or losing 
my health insurance, making these essential drugs unaffordable.''
      Sherry from North Carolina: ``I am unable to afford the biologic 
Humira even on Medicare. My monthly copay went from $5/month to $1,200/
month.''

Pfizer

About Pfizer: Pfizer's history of price hikes is as staggering as it is 
long. Here's a look at the last three years: In 2017,\12\ Pfizer raised 
the price of 91 drugs by 20 percent--that was nearly 10 times the rate 
of inflation. In mid-2018,\13\ Pfizer announced price hikes on about 
100 prescription drugs. After temporary freezes, Pfizer raised the 
raised the price of 40 drugs in January 2019.\14\
---------------------------------------------------------------------------
    \12\ https://www.ft.com/contenUb2eOdd80-47ab-11e7-8519-
9f94ee97d996.
    \13\ https://medcitynews.com/2018/07/pfizer-increases-prices-on-
100-drugs/.
    \14\ https://www.cnn.com/2018/11/16/business/pfizer-drug-prices/
index.html.
---------------------------------------------------------------------------
Questions:
      Will you commit to limiting the increase in list price of your 
drugs to the rate of inflation?
      Will you commit to submitting to this committee at the end of 
this year (2019) a report of the ways you have utilized the $10 billion 
stock buyback \15\ to serve patients?
---------------------------------------------------------------------------
    \15\ https://www.axios.com/pharma-share-buyback-tax-reform-
40a30b93-6149-4c67-bd6cd50-5ee814215.htm.
---------------------------------------------------------------------------
Patient Stories:
      Helen Sgarlat from Kingston, PA: ``Because of the $600 price 
tag, I had to switch medications. I switched from Spiriva to one that's 
not working as well, Singulair. This is outrageous.''
      Sharon from Iowa: ``I can't eat any more! My Keppra costs $460, 
Pradaxa $400, Lyrica $360. If drug prices came down, I would be able to 
eat again.''
      Susan from Nevada: ``My sister has metastatic breast cancer 
taking Ibrance. Her co-pay is $2,290/month! Without this [drug] her 
cancer will spread! She received a short term grant to help but has to 
reapply to keep receiving. This is a lifesaving drug . . . must be more 
affordable!''

Sanofi

About Sanofi: Almost 30 million\16\ Americans live with diabetes and 6 
million need insulin to survive. From 2010 to 2015, Sanofi raised the 
price of the lifesaving diabetes drug Lantus by 168 percent.\17\
---------------------------------------------------------------------------
    \16\ https://www.cbsnews.com/news/insulin-prices-rise-yet-again-
causing-diabetics-to-cry-foul/.
    \17\ https://www.nytimes.com/2016/02/21/opinion/sunday/break-up-
the-insulin-racket.html.
---------------------------------------------------------------------------
Questions:
      If PBM rebates were eliminated, would you lower your list 
prices?
      Will you commit to undoing the dozens of times you've raised the 
price of Lantus and lower the list price this year?
      As the Chairman of the lobbying group, PhRMA, your organization 
spent $27.5 million on lobbying in 2018.\18\ Next year, will you agree 
to take half that money and use it to lower drug prices across the 
board for patients?
---------------------------------------------------------------------------
    \18\ https://www.statnews.com/2019/01/22/phrma-spent-a-record-
breaking-27-5-million-on-lobbying-in-2018-new-filings-show/.
---------------------------------------------------------------------------
Patient Stories:
      Jerraline Krawetzki from Berlin Heights, OH: ``Because of 
diabetes type 2, Lantus and Humalog are required. Because of the 
increased costs of these medications, after filling the first 
prescriptions, already IN the donut hole. This means a one month 
prescription of these 2 drugs, will cost over $600 per month. Senior 
citizens on a fixed income cannot afford this.''
      David from Nevada: ``I have to take Lantus and Januvia for my 
Diabetes and Xeralto for my AFIB and many other medications for my 
heart, blood pressure, cholesterol, and BPH. These medications are very 
expensive and I can't afford them after I reach the Medicare Part D 
donut hole. Medicare prohibits free medications or discounts so living 
on social security means I will eventually die from lack of medicine.''
      Jeannie from Kansas: ``I am a type 2 diabetic. I take Lantus 
insulin. One month supply is $128 with insurance. I am single and on 
Social Security of $942 a month. How am I to pay for the insulin that 
keeps me alive?''

Merck & Co. Inc.

About Merck: Merck is no stranger to drug price increases. From January 
2017 to mid-2018, Merck raised the price of Januvia by nearly 20 
percent.\19\ In November 2018, the corporation raised the price on five 
drugs,\20\ including top-selling Gardasil and Keytruda.
---------------------------------------------------------------------------
    \19\ https://www.latimes.com/business/hiltzik/la-fi-hiltzik-drug-
prices-20181206-story.html.
    \20\ https://www.reuters.com/article/us-merck-co-drugprices/merck-
raised-prices-five-drugs-including-keytruda-in-november-idUSKCN1NX2ZN.
---------------------------------------------------------------------------
Questions:
      Will you submit, for the record, the cost of research and 
development for the drug Keytruda, which reaped \21\ a total of $1.89 
billion the third quarter of 2018 alone--an increase of 80% since 2017?
---------------------------------------------------------------------------
    \21\ https://www.bloomberg.com/news/articles/2018-10-25/merck-
plans-10-billion-buyback-as-cancer-drug-tops-estimates.
---------------------------------------------------------------------------
      Your company recently spent $10 billion on stock buybacks.\22\ 
This year, will you commit to decreasing drug prices by that same 
amount?
---------------------------------------------------------------------------
    \22\ https://www.bloomberg.com/news/articles/2018-10-25/merck-
plans-10-billion-buyback-as-cancer-drug-tops-estimates.
---------------------------------------------------------------------------
Patient Stories:
      Stephen Hadfield from Charlotte, NC: ``I am on very expensive 
insulin for my diabetes. My Januvia is $400 a month and my Lantus is 
$350 every three weeks. If it was not for insurance, I would not be 
able to afford these drugs.''
      Yvonne from Georgia: ``I can't afford the medicines I need to 
treat my diabetes. Januvia costs over $200, and with my other 
medications too I am in the donut hole, making it hard to manage my 
disease.''
      Mark from Louisiana: ``I have extremely high cholesterol and I 
am allergic to statins. The only medication that I can take would be 
Zetia which costs $800 for 3 month supply after insurance coverage. The 
same drug is available in Canada for $150 for a 3 month supply and no 
insurance coverage!''

Johnson & Johnson

About Johnson & Johnson: Since 2012, Johnson & Johnson has raised the 
price of its blockbuster drug Xarelto by 87 percent.\23\ In January of 
2019, the company raised the price on about two dozen drugs.\24\
---------------------------------------------------------------------------
    \23\ https://www.i-mak.org/wp-content/uploads/2018/08/I-MAK-
Overpatented-Overpriced-Report.pdf.
    \24\ https://www.reuters.com/article/us-johnson-johnson-
drugpricing/jj-raises-u-s-prices-on-around-two-dozen drugs-
idUSKCN1P42VY.
---------------------------------------------------------------------------
Questions:
      Will you commit to holding your price increases to inflation 
each year?
      Will you commit to striking a deal with the New York Drug 
Utilization Review Board if they deem it necessary to decrease the cost 
of Remicade for state taxpayers?
Patient Stories:
      Sarah Pekarske from Texas: ``I have Lupus and I have had 3 blood 
clot episodes. I take Xarelto. In August of last year it was suddenly 
$100/month. It has cost $150/month since September! This is too 
expensive for me.''
      Diane from Georgia: ``I have been on Remicade since 2013, but 
when I retire I won't be able to take it anymore because of change in 
insurance and higher co-pays. I don't know what I'll do.''
      Patricia from Texas: ``I am on fixed income because I am 
disabled with rheumatoid arthritis. I need infusions for Simponi Aria I 
cannot afford. Even with help to pay for the infusion, my part is going 
to be over $500 per month. That is half of my income every month.''

Bristol-Myers Squibb Co.

About Bristol-Myers Squibb: Over the last eight years, Bristol-Myers 
Squibb has spent over $25 million \25\ in lobbying expenditures and 
$1.75 million \26\ in campaign contributions, according to Open 
Secrets. The company raised the price of its blockbuster drug Eliquis 
by 6 percent \27\ in January 2019. Last year alone, U.S. Patients' paid 
Bristol-Myers Squibb $3.8 billion \28\ for Eliquis, a 30 percent \29\ 
year-over-year increase.
---------------------------------------------------------------------------
    \25\ https://www.opensecrets.org/orgs/
summary.php?id=D000000149&cycle=2018.
    \26\ https://www.opensecrets.org/orgs/
summary.php?id=D000000149&cycle=2018.
    \27\ https://www.foxbusiness.com/healthcare/meet-the-big-pharma-
ceos-who-will-testify-in-the-senate.
    \28\ https://www.foxbusiness.com/healthcare/meet-the-big-pharma-
ceos-who-will-testify-in-the-senate.
    \29\ https://www.foxbusiness.com/healthcare/meet-the-big-pharma-
ceos-who-will-testify-in-the-senate.
---------------------------------------------------------------------------
Questions:
      Will you commit to donating 50% less to candidates for public 
office in 2020 and investing that money toward research and development 
or decreasing price for patients?
      With your recent acquisition of Celgene, will you commit to 
ending Celgene's use of the REMS program to prevent a generic from 
coming to market for its blockbuster drug, Revlimid?
      Do you support the CREATES Act?
Patient Stories:
      Elizabeth from New Jersey: ``The greed of Bristol-Myers-Squibb 
is horrible. Now I have to decide if I should just take asprin each day 
and hope I don't have a stroke or pay the high cost each month for 
Eliquis for $145 per month.''
      Gail from Michigan: ``I didn't have coverage for a year and the 
Eliquis I need costs $400 per month. It's a crying shame that these 
drugs are so expensive. I had to stretch the script out by taking them 
every other day.''
      Tara from Kansas: ``Drug prices are killing me faster than the 
disease. When I first started taking my blood thinner a few years ago, 
I thought $400 a month was terrible. Now, I wonder how I can possibly 
afford the next dose of Opdivo. I can't. Without it I die. With it I go 
broke. What kind of choice is that? No one should ever be put in this 
position. No one should make this choice ever.''

AstraZeneca

About AstraZeneca: AstraZeneca has a history of charging cancer 
patients high prices. Here are three examples: Imfinzi costs $180,000 
per year \30\ for lung cancer, Lynparza costs around $15,000 for 112 
pills \31\ for ovarian cancer, and Iressa costs $8,000for 30 pills \32\ 
lung cancer. And before AstraZeneca faced a generic competitor for its 
high cholesterol drug, Crestor, the company raised prices multiple 
times, including by about 15 percent \33\ right before a generic 
competitor came to market.
---------------------------------------------------------------------------
    \30\ https://professionals.optumrx.com/content/dam/optum3/
professional-optumrx/news/rxnews/drug-approvals/
drugapprovals_imfinzi_2017-0502.pdf.
    \31\ https://www.goodrx.com/lynparza/medicare-coverage.
    \32\ https://www.goodrx.com/iressa.
    \33\ https://www.marketwatch.com/story/big-pharma-games-the-system-
to-make-generic-drugs-more-expensive-2018-07-27.
---------------------------------------------------------------------------
Question:
      Will you submit for the record the following information: the 
amount you have spent on research and development vs. AstraZeneca's 
yearly budget for marketing and advertising?
Patient Stories:
      Teresa Bianco from Elyria, OH said: ``We have a family history 
of dangerously high cholesterol levels. My sister and I have been on 
every medicine out there. The only one that lowers us into the high 
200's is Crestor. It is not covered by our insurances and thus is out 
of our reach. Sadly, we are both RNs and see others also go through 
this. We are college educated, helping people, always gainfully 
employed full time, but we are apparently disposable.''
      Linda Schoene from Pikesville, MD said: ``I have GERD and am 
prescribed Nexium. On Medicare Part D, my copay is a little over $100 
per month. I can't afford that. So I go without which causes me sharp 
pains in my stomach when I have a flair. I sometimes buy the over the 
counter version, but it is half the strength of what I am prescribed 
and doesn't treat my symptoms.''
      Silvio from Pennsylvania: ``I was taking Crestor but the prices 
kept rising and because I am on Medicare I was not eligible for a 
discount. So I had to stop taking it. Next time I got a blood test my 
bad cholesterol skyrocketed.''

                                 ______
                                 
               Pharmaceutical Care Management Association

                     325 7th Street, NW, Suite 900

                         Washington, DC, 20004

Introduction

The Pharmaceutical Care Management Association (PCMA) is the national 
association representing America's pharmacy benefit managers (PBMs), 
which administer prescription drug plans for more than 266 million 
Americans with health coverage provided through Fortune 500 employers, 
health insurers, labor unions, Medicare, Medicaid, and the Federal 
Employees Health Benefits Program (FEHBP).

PBMs are the primary advocate for consumers and health plans in the 
fight to keep prescription drugs accessible and affordable. PBMs 
negotiate on behalf of consumers, and work to keep a lid on overall 
costs for prescription drugs with market-based tools that encourage 
competition among drug manufacturers and pharmacies, and incentivize 
consumers to take the most cost effective and clinically appropriate 
medication.

By leveraging competition among manufacturers, PBMs save patients and 
health plans $123 per prescription, and will negotiate prescription 
drug costs down $654 billion over the ten years ending 2025.\1\
---------------------------------------------------------------------------
    \1\ Visante, ``Pharmacy Benefit Managers (PBMs): Generating Savings 
for Plan Sponsors and Consumers,'' February 2016, https://
www.pcmanet.org/wp-content/uploads/2016/08/visante-pbm-savings-feb-
2016.pdf.

PBMs manage Medicare Part D drug benefits through insurers, either as 
contractual service providers to stand-alone Prescription Drug Plans 
(PDPs) or Medicare Advantage plans that offer prescription drug 
---------------------------------------------------------------------------
coverage (MA-PDs).

PBMs are proud of their performance in Part D. PBMs and Part D sponsors 
have kept overall program costs 30 percent below original government 
projections, offered beneficiaries lower-than-expected premiums, and 
generated high levels of generic utilization while providing broad 
choice of drugs and access to over 60,000 pharmacies, all while 
attaining a continually high rate of beneficiary satisfaction.

PBMs Negotiate to Keep Drug Spending Manageable

The most recent available data, which is for years 2016 and 2017, show 
that the overall growth in spending for all prescription drugs has been 
low.\2\ tallying 1.4% and -0.3% for 2016 and 2017, respectively. Drug 
industry stakeholders rightly trumpet such figures to show the success 
of private-sector negotiation in bringing spending discipline to the 
prescription drug market.
---------------------------------------------------------------------------
    \2\ KFF, ``What Are the Recent and Forecasted Trends in 
Prescription Drug Spending?'', February 20, 2019, https://
www.healthsystemtracker.org/chart-collection/recent-forecasted-trends-
prescription-drug-spending/#item-start.

However, the totals mask the dynamics at work in different sectors of 
the prescription drug market. Spending on generic drugs has actually 
been declining, while spending on brands has been increasing. According 
to a November 2018 analysis, for the previous year, spending on brands 
increased 4% while spending on generics decreased 3%.\3\
---------------------------------------------------------------------------
    \3\ Blue Cross Blue Shield Association, ``Prescription Drug Cost 
Trend Update,'' November 14, 2018, https://www.bcbs.com/the-health-of-
america/reports/prescription-drug-costs-trend-update.

Further, the report indicates that while brand drugs made up only 17% 
of total prescriptions, they accounted for 79% of overall drug spending 
in the previous year.\4\
---------------------------------------------------------------------------
    \4\ BCBSA, Op. Cit.

Data underlying the overall spending figures shows that manufacturers 
have been increasing the prices they set for their drugs rapidly. 
According to IQVIA data, for the 5-year period ending 2017, brand 
invoice price grew at an average annual rate of 10.5%, while overall 
inflation in the economy, as measured by CPI-U, grew at an average 
annual rate of 1.3%.\5\ These trends are mirrored in a study conducted 
on drugs most used by the elderly. A 2018 AARP analysis found retail 
prices for 113 chronic-use brand name drugs on the market since at 
least 2006 increased cumulatively over 12 years by an average of 214 
percent, compared with the cumulative general inflation rate of 25 
percent from 2006 to 2017.\6\
---------------------------------------------------------------------------
    \5\ https://www.iqvia.com/institute/reports/medicine-use-and-
spending-in-the-us-review-of-2017-outlook-to-2022.
    \6\ AARP, ``No End in Sight for Skyrocketing Prescription Drug 
Prices,'' September 26, 2018.

The near-flat overall trend for spending on all drugs, despite rising 
prices and spending for brands, illustrates the work that PBMs do as 
advocates for patients and their client health plans to hold the line 
on prescription drug costs.

Drug Manufacturers Alone Set and Raise Prescription Drug Prices

As the Committee continues its work with respect to prescription drug 
costs, one thing is clear: only manufacturers have the power to set or 
change prices. In recent years, brand manufacturers and their allies 
have attempted to deflect blame for the prices they set by blaming 
other parties in the drug supply chain,\7\ including pharmacies, PBMs, 
and wholesalers. While much has been said and written, research studies 
show that there is no correlation between the prices manufacturers set 
and the rebates PBMs negotiate with manufacturers.
---------------------------------------------------------------------------
    \7\ See, e.g., https://www.phrma.org/press-release/new-report-
shows-how-supply-chain-shapes-brand-name-medicine-prices.

A 2018 study found no correlation between the prices that brand drug 
manufacturers set for individual drugs and the rebates that they 
negotiate with PBMs on those products (see chart below).\8\ The data in 
the scatter plot below show that increasing list prices over a 5-year 
period were not correlated with changes in rebates (R\2\=0.016), as 
shown with the horizontal blue line. Additionally, there are prominent 
cases of higher-than-average price increases on brand drugs where 
rebates stayed the same or declined (e.g., Humulin).
---------------------------------------------------------------------------
    \8\ Visante, ``Increasing Prices Set by Drugmakers Not Correlated 
With Rebates: An Analysis Prepared by Visante on Behalf of PCMA,'' June 
2017.

[GRAPHIC(S) NOT AVAILABLE IN TIFF FORMAT]  


At the same time, separate research confirmed that negotiated rebates 
are correlated with competition-that the size of drug rebates is 
positively correlated with the extent to which a given brand drug faces 
competition in the market.\9\
---------------------------------------------------------------------------
    \9\ Credit Suisse Equity Research, ``Global Pharma and Biotech,'' 
April 18, 2017.

Other research sponsored in part by a multinational brand drug 
manufacturing firm reports that, for every $100 spent in the drug 
supply chain on branded drugs, manufacturers capture $58. This 
contrasts sharply with the amounts captured by pharmacies ($3), PBMs 
($2), and wholesalers ($1).\10\ These results show that it is the 
manufacturers who benefit far more than any other party in the drug 
supply chain, and any rhetoric to the contrary is a smokescreen.
---------------------------------------------------------------------------
    \10\ Sood, N. et al. ``The Flow of Money Through the Pharmaceutical 
Distribution System,'' University of Southern California, Leonard D. 
Schaeffer Center for Health Policy and Economics, June 2017, https://
healthpolicy.usc.edu/wp-content/uploads/2017/06/USC_Flow-of-Money
WhitePaper_Final_Spreads.pdf.

Further illustrating the lack of any connection of manufacturer list 
prices to negotiated rebates is the chart below containing Part B 
pricing data. Drugs under Medicare Part B typically carry no rebates. 
The chart shows that several unrebated branded drugs have posted price 
increases vastly outpacing the rate of inflation, as well as the rate 
of price increases among most drugs. Moreover, unrebated drugs in 
Medicare are not unique to Part B--HHS's Office of the Inspector 
General finds a full 39% of branded drugs in Part D carry no 
rebatex.\11\
---------------------------------------------------------------------------
    \11\ HHS Office of the Inspector General, ``Increases in 
Reimbursement for Brand-Name Drugs in Part D,'' June 2018.

                        Selected Part B Drugs With High Price Increases From 2017 to 2018
----------------------------------------------------------------------------------------------------------------
                                                             Estimated                  Estimatied
                                              2012 Price     2017 Price     % Price     2018 Price     % Price
                 Brand Name                   per Part B     per Part B     Increase    per Part B     Increase
                                             Prescription  Prescription*    2012-17    Prescription    2012-17
----------------------------------------------------------------------------------------------------------------
Miacalcin                                            $461        $16,375       3,449%       $19,266          18%
Krystexxa                                          $2,717        $19,163         605%       $21,127          10%
Teflaro                                              $110           $399         263%          $439          10%
Bicillin                                              $41           $106         159%          $120          13%
Rituxan                                            $5,125         $6,890          34%        $7,416           8%
Orencia                                            $1,636         $2,849          74%        $3,020           6%
----------------------------------------------------------------------------------------------------------------
* Estimated inflation adjusted price = 2012 price * weighted average manufacturer increase in list price per
  unit. Not affected by changes in numbers of units per claim, or mix of doses/dosage forms. Estimated 2018
  price through Q3 2018. During study years PBMs were not involved in Medicare Part B program, so no PBM rebates
  were involved. Analysis included drugs with Part B spending data for full period 2012-16.
Source: Visante and PCMA analysis of data from CMS and SSR Health, 2019.


In sum, the research record is clear: drug manufacturers alone are 
responsible for the prices they set and neither PBM-negotiated rebates, 
nor any other party nor factor in the supply chain affects the list 
price of a brand drug.

Managing Drug Cost Growth Is Challenging, but Policy Changes Could 
                    Improve Competition

PBMs have an established record of negotiating with manufacturers and 
pharmacies to reduce costs for patients, either in the form of lower 
premiums for all participants in a plan, or through lower costs at the 
pharmacy, and usually both.

The key to reducing prescription drug costs is increasing and 
encouraging competition. PBMs are best able to negotiate when 
competition exists, and PCMA's member companies support a number of 
ideas for increasing competition and building upon market-based tools 
to improve the Part D program. These include:

      Remove Part D's protected classes. Designating ``classes of 
clinical concern'' where all or substantially all drugs in a class must 
be covered allows drug manufacturers to virtually name their price. 
Indeed, a recent Milliman analysis showed that the average brand rebate 
(for drugs that had any rebate) in Part D was 30%, while the average 
rebate for brand drugs in protected classes was 14%.\12\ CMS already 
applies careful plan formulary coverage checks to assure proper 
coverage. A pending CMS plan only to lessen the effect of protected 
classes-not eliminate them-would save $2 billion over 10 years.
---------------------------------------------------------------------------
    \12\ Milliman, ``Prescription Drug Rebates and Part D Drug Costs: 
Analysis of Historical Medicare Part D Drug Prices and Manufacturer 
Rebates,'' July 16, 2018, https://www.ahip.org/wp-content/uploads/2018/
07/AHIP-Part-D-Rebates-20180716.pdf.

      Encourage greater use of generics for Part D LIS enrollees. 
MedPAC recommended allowing the Secretary to lower cost-sharing on 
generics and raise it for brands that have generic competition. 
Allowing plans to lower generic cost-sharing for these beneficiaries 
would save money for beneficiaries, taxpayers, and the Medicare 
---------------------------------------------------------------------------
program.

      Modify the requirement for two drugs per class. The requirement 
that Part D plans cover two drugs per class is outmoded. It has 
encouraged manufacturers to argue for ever more granular classes and 
reduced competition, increasing Part D costs. Modifying the requirement 
by requiring plans to ensure access to therapies based on conditions or 
disease states instead would reduce costs without reducing access to 
needed drugs.

      Build on existing efforts to apply Part D management tools to 
Part B drugs. PBM tools such as value-based formularies, manufacturer 
negotiation, and prior authorization have proven indispensable for 
improving patient safety and lowering costs in outpatient prescription 
drug plans like Part D. Adding Part D management tools to the Medicare 
fee-for-service program and building on efforts in Medicare Advantage 
for Part B drugs would make drugs more affordable on Medicare's medical 
side.

      Encourage use of mail-order pharmacy in Part D. Mail-order 
pharmacy: vastly reduces errors in dispensing; increases convenience 
for beneficiaries on maintenance medications; improves adherence; and 
offers a lower cost-sharing option to beneficiaries in most cases. With 
much of the public using home-
delivery for a wide range of goods and with many Medicare beneficiaries 
home-bound, CMS should take further steps to encourage home delivery of 
maintenance medications.

      Repeal any willing pharmacy provisions. Requirements that all 
pharmacies be included in Part D networks drives up costs and are 
unnecessary, given the network adequacy requirements. Congress should 
repeal the provision. One study showed that greater use of limited 
network pharmacies in Part D could generate $35 billion in savings over 
10 years.\13\
---------------------------------------------------------------------------
    \13\ Visante, ``How Pharmacy Networks Could Save Medicare, 
Medicaid, and Commercial Payers $115 Billion,'' January 2013, https://
www.pcmanet.org/wp-content/uploads/2016/10/visante-pcma-pharmacy-
networks-study-1-13.pdf.

      Give Part D plans meaningful access to Part A and B claims data. 
To coordinate care and make the best coverage decisions for 
beneficiaries, plans need to be able to use medical data as well as Rx 
data. Existing prohibitions on using A and B data to inform coverage 
design and decisions are misguided and keep plans from using claims 
data to improve care coordination and coverage. Researchers suggest 
combined data sets of Parts A, B, and D claims can be a ``rich 
---------------------------------------------------------------------------
resource'' for comparative effectiveness data.

The following list of additional solutions would further increase 
competition in the marketplace. While these proposals are outside the 
Finance Committee's jurisdiction, they should help to bring balance 
back to the drug marketplace and enhance competition.

      Eliminate use of Risk Evaluation and Mitigation Strategies 
(REMS) to delay competition. Some manufacturers have used REMS to 
prevent generic or biosimilar developers from getting sufficient 
quantities of a drug or biologic to develop a competitor to the 
innovator product. REMS were never intended for this purpose; this 
practice should be prohibited. S. 340, ``Creating and Restoring Equal 
Access to Equivalent Samples Act of 2019'' or the ``CREATES Act of 
2019'' would address these abuses.

      Stop anticompetitive product adjustments, i.e., 
``evergreening.'' Drug manufacturers sometimes use tactics such as 
``product hopping'' or ``evergreening,'' submitting applications to the 
FDA for approval of a ``new'' product that is essentially the same as 
the original product. These product lifecycle management tactics 
artificially extend drug exclusivity periods and delay the take-up of 
lower-cost generics.

      End orphan drug exclusivity abuses. Orphan drug exclusivities 
are meant to encourage research on rare diseases, but manufacturers 
have gamed the policy to apply it to blockbuster drugs with script 
volume in the tens of millions. Orphan exclusivity periods should only 
apply to those drugs originally approved by FDA under an orphan 
indication and only for the orphan indication itself.

      Eliminate ``pay-for-delay'' agreements. Patent settlements, or 
``pay-for- delay'' agreements, allow drug patent holders to pay off 
potential competitors who would otherwise produce a competing generic 
or biosimilar drug. These anticompetitive agreements should be 
eliminated. S. 64, The Preserve Access to Affordable Generics and 
Biosimilars Act, would greatly ameliorate these concerns.

      Allow for FDA accelerated approval of brand drugs based on 
increasing competition. Accelerated review is granted to new drug 
applications that address ``unmet need.'' The economic need for 
competition to lower prices, or what some call ``financial toxicity,'' 
should be a criterion of unmet need.

      Revisit and improve biosimilar labeling and naming. 
Substitutable biosimilars should bear identical names and labels to 
their innovator analogs. Use of different names will confuse patients 
and providers and inhibit prescribing of biosimilars.

      Reduce innovator biologic exclusivity to 7 years. Seven years of 
data exclusivity would still provide a sufficient return to 
manufacturers, while also speeding more affordable biosimilars to 
market.

These policies and some of the specific bills that contain them can 
help lower costs in Part D and the wider prescription drug market.

Part D Should Work for All Enrollees, but the Administration's Proposed 
                    Rule Ending Drug Rebates Is Counterproductive

In addition to the suggested policy changes above, specific 
interventions to help Part D beneficiaries who have high out-of-pocket 
spending are needed. Fourteen years into the program, it remains a 
great success with high enrollee satisfaction, however, policymakers 
should consider how best to balance the needs of all Part D enrollees.

With respect to the Administration's recently proposed rule to end the 
drug rebate safe harbor, there is grave concern that this proposed rule 
would increase premiums for Medicare beneficiaries and costs for 
taxpayers.

While the Administration's goals are well intentioned, the proposed 
rule does nothing to reduce the prices drug manufacturers set. To the 
contrary, it would cause substantial increases in seniors' Part D 
premiums, as well as the cost to taxpayers.

The Administration's proposal also includes an unprecedented six 
different cost impact estimates by three different actuarial groups, 
including the independent HHS Office of the Actuary (OACT). The range 
of impact for cost to the federal government across the six estimates 
is an immense $300 billion. The great uncertainty surrounding the 
proposal should give the Committee pause. Americans deserve clarity on 
how such a proposal will affect those who rely on Medicare and 
Medicaid, and commercial coverage. Given OACT's skill and institutional 
independence from the agency, it is likely they have the most accurate 
estimates.

Under the Administration's proposal, according to OACT, Part D premiums 
could rise by as much as 25 percent for 2020 to reach $47.66, marking 
the largest average premium increase in the program's history. Such a 
large increase could cause many seniors and disabled Americans to drop 
the prescription drug coverage they need to protect their health and 
financial security, or never sign up in the first place. Healthier 
beneficiaries (i.e., those who need fewer drugs) would drop coverage 
first, causing premiums to increase further and potentially 
destabilizing the Part D program, as increasingly those eligible for 
enrollment would find Part D coverage unaffordable.

Additionally, OACT estimates that the proposal would cost the federal 
government an extra $196 billion over the next 10 years. If finalized, 
this could make the proposed rule among the costliest in U.S. 
history.\14\
---------------------------------------------------------------------------
    \14\ American Action Forum, ``Mandating Talking Cars: Costliest and 
Most Beneficial?'', December 16, 2016. This article describes what were 
at the time, the two costliest proposed regulations in U.S. history. 
The OACT cost estimate for the Administration's proposal is in excess 
of these two, https://www.americanactionforum.org/regulation-review/
mandating-talking-cars-costliest-beneficial/.

PCMA urges the Committee to encourage the Administration to withdraw, 
or at the very least significantly delay the implementation of, the 
proposed rule until its impact on beneficiaries and on Part D can be 
better understood and managed.

Conclusion

In the search for solutions to address high drug costs, the Committee 
and Congress would be best served in pursuing policies that foster and 
encourage competition to keep prescription drug costs and pharmacy 
benefits more affordable for employers, enrollees, taxpayers, and 
government programs. Unfortunately, the rule recently proposed by the 
Administration will not accomplish this goal, since it does nothing to 
encourage manufacturers to bring down the drug prices they alone set.

PCMA member companies welcome continuing discussion among all 
stakeholders to create a robust, sustainable market that will continue 
to deliver needed cures and treatments for patients who suffer through 
disease and chronic illness.

                                 ______
                                 
                  Letter Submitted by Debra L. Raffle
February 27, 2019

U.S. Senate
Committee on Finance
Dirksen Senate Office Bldg.
Washington, DC 20510-6200

RE: The Escalating and Unsustainable Rising Cost of Insulin for 
Insulin-Dependent Diabetics

Chairman Grassley and the Committee:

I hope I am not too late and will be read at least. I only received 
this notification a few days ago from the American Diabetes 
Association, but I see you continue to have hearings, so I am revising 
and resending my letter.

I have type 1 diabetes. I am an insulin-dependent diabetic, which means 
there's not one hour of every single day of my life that I MUST have 
insulin, or I will die. It's that simple. I was diagnosed around 9-11, 
sadly that it makes it easy to remember. I was an adult diagnosed with 
a mostly childhood disease and had a lot to learn! The cost of insulin 
that I need to stay alive 24 hours a day has escalated from $70 per 
1000 ml vial to nearly $300 a bottle. The same bottle of Novolog sells 
for $47.99 in Canada. I just had to pay $2300 out of pocket for 3 
months of insulin (and that was with a supposed discount)! The 
insurance I have through my employer has an extremely high deductible 
and high copays and some items are not covered at all. If my insulin 
pump supplies are not covered, I simply cannot afford them. If I can't 
afford to manage my diabetes the way my doctor and I have been doing 
successfully through pump therapy all these years, I will likely get 
sick, get a complication or two and then die. And no one seems to care! 
Certainly not the insurance companies or the pharmacies. People need to 
care. It will cost far more with the complications that will arise if I 
don't get my insulin and if I can't afford to pay it, other tax payers 
will ultimately bear those costs when all of this can be avoided. 
Again, I feel that most insurance companies and certainly the 
pharmacies prefer their profits over actual health care and effective 
management and if we can't afford the astronomical prices they are 
putting on once affordable drugs and supplies, then they would prefer 
we die and let someone else pay. This is insane to me! I should be able 
to afford my insulin and pump supplies, as in the past, but due to 
escalating prices of medications, insulin and insurance costs (so they 
can all make their profits) it is becoming unsustainable. I can't 
afford it and am very healthy and have a good paying job.

I would like to join in the battle to fight insurance companies who 
seem to think we can do without these drugs--insulin is not even a 
drug, it's something my body quit making almost 20 years ago and that 
most of you all take for granted, but without it, I will, in fact, die 
within a few days/possibly lingering a few weeks in a coma. I didn't 
ask for this, however, if I am able to get what I need, what my doctor 
prescribes for me and have that covered by my insurance, I remain 
healthy. I am a working, productive, tax paying citizen and if you 
allow me to get insulin and medical supplies at a sustainable price, I 
can continue to be a productive tax paying citizen. If you don't I 
become unable to work, pay taxes and get sicker and die. Diabetes is a 
completely manageable disease and it's disheartening that the insurance 
companies, the pharmacies and the United States Government seem to have 
such low regard for those of us who were unfortunate to contract a 
disease where we have NO OPTION but to buy insulin at escalating 
prices. They keep raising the price of insulin higher and higher and 
higher, because they have a captive audience they are holding hostage. 
I really wish someone would take a stand on this and I would be willing 
to help, testify, or whatever it takes to help this situation.

In addition, I also take a medication called Symlin that allows me to 
utilize my insulin more efficiently. It decreases my insulin intake 
about 30%. This helps me maintain a healthy weight. More insulin means 
more weight and more weight means taking more insulin. It's a vicious 
circle. I am a type 1 so I have never been over weight and I struggle 
to maintain my weight for the reasons I have listed above. If I can 
maintain my weight, not only will I be healthier, but I can take 
slightly less insulin to help combat the astronomical cost of something 
that I MUST HAVE EVERY SINGLE DAY OF MY LIFE. By reducing my intake by 
10 units a day, I may get another day or two out each vial and that's a 
lot! It certainly will NOT help my overall health to put on extra 
pounds! Anyhow, my new insurance will not cover Symlin at all and they 
tell me it will cost $5800 for a 3 month's supply that I used to pay 
$70 co-pay when I had Premera. I have been on this drug about 10 years. 
This is ridiculous and clearly, I cannot afford this, so I get to go 
off it cold turkey, increase my insulin intake and pay more than I ever 
have for the same insulin!

I don't think they understand how this all works nor do insurance 
companies and administrators care, but if you give us the tools 
(medications and supplies) to manage our diseases with, we will not 
have as many costly complications. So, it is cost-effective to give us 
what we need now to avoid higher costs of complications later! To date, 
since I was diagnosed as a type 1 in 2001 and having been on an insulin 
pump for 17-18 years, I have never had any complications due to my 
diabetes and would like to keep it that way.

I am so disgusted with insurance companies and I want to know what we 
can do to get things changed. Can I go up to Canada and purchase my 
insulin? Can I testify and be a witness? I am willing to do whatever I 
can to help! What can I do to lower my medication and durable medical 
equipment costs? The insurance company cannot even tell me what things 
cost until I purchase them, which is ridiculous since I don't want to 
pay for things I clearly cannot afford. I'm lost and feeling desperate. 
I look to your committee to make this manageable disease financially 
manageable. It is manageable if we can afford what we need to survive 
and there's NO reason for the price to quadruple in the last 10 years, 
NONE except for greed and profits.

I spent over $6.5K last year on out pocket medical costs, mostly 
insulin and pump supplies. I had no surgeries, I had no illnesses, I 
had no procedures. This is becoming very difficult to afford.

I don't think I should have to struggle to afford groceries and lose my 
home or just make simple choices because I can't afford my insulin and 
supplies. Please do something about the escalating cost of health care, 
specifically common insulin, Novolog in my case, and do what you have 
promised for many years! This is unsustainable as it currently is!

Thank you for listening.

Debra L. Raffle

                                 ______
                                 
                   Letter Submitted by Laura T. Ricci
March 4, 2019

U.S. Senate
Committee on Finance
Dirksen Senate Office Building
Washington, DC 20510-6200

RE: February 26, 2019, ``Drug Pricing in America: A Prescription for 
Change, Part II''

To the Senate Committee on Finance,

Thank you for beginning to tackle the outrageous prices of prescription 
drugs in America. I've watched many of the meetings and also the 
Congressional Oversight meeting with Congressman Cummings. I watched 
this meeting again and took notes. What I find interesting is several 
of the ``Magnificent Seven'' are foreigners. These are CEOs that have 
come to America to use Americans and the American healthcare system as 
pawns for their profits. I do think that it is a multi-layered problem 
and the American healthcare system is to blame for a lot of it. The 
first thing that the senate and congress need to do is regulate this 
industry so these people have to abide by stricter laws. All of the 
levels need to abide by stricter laws.

I come to you as a mother of a type 1 diabetic, 20 years old, who will 
soon be on his own. What will happen to him if he has to enter a high 
deductible healthcare plan one day? Will he be the next Alec Smith or 
Antavia Worsham? I would like to see this system fixed before he has to 
cross that road. I am lucky enough to live in the Commonwealth of 
Massachusetts, where he is eligible for Masshealth benefits so I am not 
taxed in my wallet for his insulin. But one day, under the current 
system, he may be. What if he ever wants to move out of Massachusetts? 
What kind of healthcare plan will he be forced into? The current system 
is designed for failure for a T1 diabetic. The only way T1s can get 
their insulin for free or cheap is to make less than $16,000 or just 
work a part-time job so you will qualify financially. What kind of 
contribution to society is that? Will he ever be able to use the 
college degree he will earn? He might end up living at home for the 
rest of his life to be able to afford insulin because he will never be 
able to afford $324.00 for a bottle of insulin or the ridiculous copays 
assessed and high deductibles. High deductible healthcare plans need to 
be abolished. High deductible healthcare plans are only for the really 
healthy, they're not for anyone who needs to use the system, the only 
system in place. T1s are forced to use the system because insulin is 
not available over the counter like a loaf of bread is. My son can't 
buy and eat the bread if he doesn't have the insulin to go with it.

Why does America not allow insulin to be purchased over the counter 
without a prescription? Why does America not trust Americans to use 
insulin correctly? I want insulin to be able to be purchased over the 
counter, maybe with a prescription, but no insurance attached to it. 
When you look at the supply chain of food, there's a manufacturer, a 
warehouse and distributor, the supermarket and then the consumer. When 
you look at the supply chain of medicine, there's the manufacturer, the 
warehouse and distributor, the pharmacy (supermarket), the consumer and 
then the PBMS and insurance companies. If the PBMS and insurance 
companies were eliminated from this chain, then the prices would come 
down because there would be no clawbacks and rebates involved. Is there 
a rebate for bread? No.

My son was diagnosed with T1 diabetes in 2007. I was looking at some of 
my old receipts. I looked at one from 2010. The price that Blue Cross 
paid was $390.13 for 6 bottles of humalog. I had a $60 copay. That was 
$75.00 a bottle, but I only paid $10.00 a bottle with the copay. The 
lantus insulin was $152.48 that the insurance paid, and I paid $60.00. 
I got 3 bottles. So that was $212.48 divided by 3 is $70.82. I paid 
$20.00 for each bottle with the $60.00 copay. Today, I see the receipt 
from Walgreen's, and the cash price is $974.89 for 3 bottles of 
humalog. That's $324.96 each. That is what the Commonwealth of 
Massachusetts must pay because he is covered under Masshealth. Does 
Massachusetts pay that much? I have a feeling they do because Medicaid 
is not allowed to negotiate prices with drug companies. The budget for 
Massachusetts is 40% healthcare. Former Gov. Mitt Romney put this 
mandatory healthcare in place. This should have been used as the 
template for the ACA. Did the ACA cause these high deductible 
healthcare plans? Some people think it did. That's a question I have 
for you. Did the ACA cause high deductible plans? High deductible plans 
are bankrupting Americans. They're causing people to have to pay 
upwards to $25,000.00 sometimes for drug coverage before insurance will 
pay anything. It's unaffordable. People are selling their houses, 
taking out second and third mortgages, moving back home with mom and 
dad, and even living on the streets.

You've heard the stories about people rationing insulin and dying. I 
don't want that to happen to my son. T1 diabetes will never go away. 
There is no cure. The pharmaceutical companies know there is no cure 
and know we are at their mercy. The American lawmakers allow them to 
carry on. You need to regulate this industry and put the brakes on 
their practices. Utilities, food, tobacco, guns, are all regulated. 
It's time for pharmaceutical companies to be held accountable so they 
will stop using Americans as pawns for profit. As said in the hearing, 
they make money on their drugs in Germany. If they didn't, they would 
say goodbye to Germany.

When people can go to Mexico and buy the insulin for $30.00 a bottle, 
Canada for $35-45.00 a bottle, then that tells you that the price to 
produce it is low. I read an article that showed a study that said it 
only costs $3-6.00 to produce a bottle of insulin. It's just like the 
EpiPen. Heather Bresch, the CEO of Mylan, she told the Senate that it 
costs Mylan $1.00 to make it, they sell it for $60.00 and it retailed 
for $300.00! That's nuts. A lot of EpiPens never even get used. They're 
there for an emergency. Insulin is used anywhere from 4-10 times a day 
because you need to take it every time you eat. You don't need an 
EpiPen every time you eat. The equivalent to an EpiPen for a diabetic 
is a device called a glucagon injection. It is also very expensive and 
is often never used. It's an injection that will revive you from a low 
blood sugar if you pass out and may have a seizure. According to GoodRX 
website, the glucagon retails for $292.81 which is 19% off the retail 
price of $364.50. This is another device that often goes unused, but 
people pay for it because they want it in case of emergency. There are 
no coupons available to get it for free. I would like to know how much 
it really costs to manufacture a glucagon kit.

The other thing that people are doing to get insulin is they're taking 
out gofundme accounts. They try to raise money to pay for the copays. 
They don't always succeed in raising the money and still end up dead, 
which is the case with a man named Shane Patrick Boyle. People then 
have to take out gofundme accounts to bury their loved ones because 
once you are diagnosed with T1 diabetes, you have a lot of difficulty 
in getting life insurance. You're a threat to insurance companies. They 
only want to bring money in, they don't want to pay it out. But they 
pay it out to CEOs in the form of huge salaries.

All of the CEOs at every level of the supply chain make a lot of money. 
David Ricks, CEO of Eli Lilly, he makes $40,000.00 a day in salary. 
$5,000.00 an hour. Some people don't make $40K in two years. The CEOs 
of CVS, Walgreen's, Rite Aid, Kroger and all the insurance companies, 
like United Healthcare and Blue Cross, they also make millions. Why? 
Why is that allowed? They've all created monopolies. I've watched their 
stocks and they've all skyrocketed and I see a new CVS store in many 
towns around where I live. They've closed the old stores and built 
these fancy new buildings that are full of expensive products. I only 
get my son's insulin at Walgreen's because I am forced to get it 
locally, Medicaid will not allow you to use a 90 day pharmacy service. 
And insulin isn't the only thing that diabetics need to use for daily 
management of diabetes. They need test strips, meters, pump supplies, 
Dexcom supplies, glucose tablet s, ketone test strips, alcohol wipes, 
and sometimes they have to eat special food if they also end up with 
Celiac Disease.

There are at least 80 autoimmune diseases. There is no cure for any of 
them. Do you think the pharmaceutical companies think there is a cure 
on the horizon, a vaccine? Is that why they're raping American's to get 
their profits before people don't need insulin anymore?

Nicole Smith-Holt, the mother from Minnesota that lost her son Alec to 
rationing insulin said this in a Minnesota Roundtable: ``Before insulin 
was invented, diabetes was a death sentence. Now diabetes is a death 
sentence again because insulin is no longer affordable.'' Let that sit 
with you.

I have a change.org petition going around asking Congress to subpoena 
the CEOs of the insulin companies. One of the signers of the petition 
posted that this is the new AMERICAN GENOCIDE. Let that sit with you.

I like what Senator Wyden said about these CEOs using patients and 
taxpayers as ``unlocked ATMS.'' It's the truth. I also like what he 
said when he said ``drug prices are astronomically high because that's 
where pharmaceutical companies and investors want them, and diabetics 
who can't afford the costs self-ration and endanger their lives but the 
investor s are happy.'' It's the truth.

The CEOs were asked `'What keeps you up at night?'' None of them 
answered that they were concerned about anyone dying because they can't 
afford their medicines. They all answered that they were more concerned 
about their drugs being put on formularies. That brings me to another 
problem. The formularies. The PBMS play games all the time with the 
switching in and out of the type of insulin that the insurance company 
will pay for. This means that people often end up getting a physician's 
override to be able to continue using the insulin of their choice. The 
formulary dictates to the diabetic what they can and cannot use. They 
limit your choices or make you fight for the kind of insulin you want 
to use. Do you have the choice to buy Pepperidge Farm bread or store 
brand bread? Yes. So why doesn't the diabetic or person in need of 
medication, have the ability to choose the one that works right for 
them and not have to argue and fight for it? If the industry was 
regulated, we may have the ability to choose what is right for us, the 
patient and consumer.

Another problem I see and have stated this before, is that Congress has 
to pass legislation stopping these pharmaceutical companies from 
advertising on TV. They did it with tobacco. The last advertisement for 
tobacco was for a Virginia Slims ad on December 31, 1970 on the Johnny 
Carson show. Congress did that. So they need to do it again for 
pharmaceutical. American and New Zealand are the only countries that 
allow them to spend their profits on advertising. If they want to 
advertise, they should only be able to advertise for medicines that 
don't require a prescription. And I'm also tired of seeing 
advertisements on TV for erectile dysfunction.

Doctors: Doctors need to inform patients of alternatives to getting 
insulin and not having to use insurance. People are already buying 
insulin from Canadian Pharmacies and going to Mexico if they can. The 
State of Utah will actually pay their state employees $500.00 to cross 
the Mexican border and get their medicines there instead of having to 
put the burden on the state's budget to pay for expensive medicines in 
the U.S. Isn't that crazy? Why should that happen? If medicines were 
affordable, the drug companies wouldn't have to give so much away for 
free. The burden would be shared equally and the money would stay in 
America. And I don't buy the insulin companies' stories about the fact 
that the insulin supply chain is not protected in Mexico like it is in 
the U.S. If the insulin in Mexico were tainted, people would be dying 
from it and it would be in the news that people are dying from it 
there, and dying in foreign countries from it. So that is just a scare 
tactic to get you to continue to pay high prices to support the high 
CEO salaries.

Soriot--He said he was annoyed that he was the lowest paid CEO. Give me 
a break. That is all part of the GREED before NEED and PROFITS before 
PATIENTS.

The FDA--Mr. Gottlieb, the commissioner, he is a part of the problem 
behind insulin as well. Insulin was classified as a DRUG. He went and 
changed the classification to a BIOLOGIC. That's just a term for a 
liquid medicine. So then that created the new biosimilar insulins. 
After thinking about this, I figured out that the biosimilars didn't 
make insulin a generic, all it did was allow these insulin companies to 
take out new patents, patents that will have maybe a 20 year life span 
under the Hatch-Waxman Act. So what does that do? It creates even more 
of a monopoly. Why, after almost 100 years, is there no generic insulin 
available? No one has an answer to that. The patent for humalog is long 
since expired. All these insulin companies have to do is tweak an amino 
acid in the insulin and they get a new patent. That's ridiculous to me.

Today, March 4, 2019, there was a news article issued about Eli Lilly: 
https://investor.lilly.com/news-releases/news-release-details/lilly-
introduce-lower-priced-insulin. In this article, Eli Lilly said they 
were going to make a ``generic'' humalog and the list price of it would 
be $137.35 for a vial and $265.20 for a box of 5 pens. That is 
ridiculous to me. First, how do we know that Eli Lilly won't just use 
the humalog as it is now and just put it in a new bottle with a 
different color and change the name on it? Are they only doing this to 
appease the senate and Ms. DeGette's investigation into these high 
prices? Plus, they already have their BLINK HEALTH system, which is 
like a GoodRX, that allows you to get a vial of insulin at $178.90 and 
if you don't have insurance, you can get insulin from GoodRX for 
$177.87. These prices are lower than the $324.00, but they still aren't 
the $30.00 or $45.00 that Mexicans and Canadians reap the benefits 
from. Canada would never allow insulin to be price gouged because it 
was invented there by Sir Frederick Banting who has probably rolled 
over in his grave a million times by now. I told my congressman, James 
McGovern, that insulin wasn't supposed to be a FOR-PROFIT business. He 
turned around to me, looked me in the eyes, and said: ``Well, it is''!

The other thing about the financial aid that Eli Lilly offers, is you 
have to be really poor to be able to qualify for it. So only the poor, 
nonworking people in America can get it for free. They wouldn't have to 
give it out for free if it was affordable and accessible over the 
counter at the pharmacy. They also give a lot of insulin way to camps. 
Another thing that doctors don't tell people about is the 340B program. 
That's like a big secret, just like the other secrets that revolve 
around this industry. Many state attorney general's already have their 
own investigations going on to find out what is going on behind closed 
doors.

What I heard from some of these CEOs, especially Caforio, was that they 
``need America's help and support'' to fix this problem. I heard that 
from several of them. So they are asking YOU, the congress and the 
senate, those that write the laws, to help them figure it out because 
they know the system is unsustainable as it is and they will only 
continue to do what they are doing because there are no laws saying 
they can't do it. That's where my new hashtag comes into play--
#thepowerofthepen. Lawmakers are voted in with the power of the pen and 
lawmakers can pick up the pen and write laws to protect Americans from 
the greed of this industry.

I write to my congressman, James McGovern, and my senator, Elizabeth 
Warren, and share with them what I am sharing with you. I share that 
they need to take action and write better laws and regulate this 
industry. They also have to stop taking money from the pharmaceutical 
companies and lobbyists and don't fall for their antics. These people 
are crooked and have the thief mentality.

Mr. Frazier stated that he couldn't walk away from the U.K. even though 
they give lower prices because he believes it is immoral. But it's 
okay. that he price gouges Americans and that's not immoral?

I read in a recent article about Mr. Brandicourt, that he fought to 
keep any generic insulins out of the market and actually took out more 
patents to prevent it. So why is that allowed? That's crookedness. That 
is another case of Greed before Need. Companies like his, Sanofi, they 
give out coupons for their lantus insulin. They wouldn't have to give 
out coupons for people to get it for cheap or free if they just lowered 
the prices and made them affordable.

NovoNordisk also gives out coupons and the same applies to them. Why 
can they let you have insulin for $25.00 with the coupon, but you can't 
go to the pharmacy and get the insulin for $25.00 without the coupon? 
So you know the price to make insulin is cheap if they are able to give 
out coupons for you to get it for free or cheap.

Senator Isakson, he had quite the story. He has Parkinson's disease and 
takes 8 medicines. His story about all the ways he could get his 
medicines for cheaper were right on target. The options: Don't use 
insurance, use coupons, get rebates or just pay CASH. People could just 
pay cash if they didn't have to pay and arm and a leg for medicines 
that are supposed to keep you alive, not kill you because you can't 
afford them. And his story about his staff member's 2nd child being 
diagnosed with T1 diabetes was heartbreaking. T1 diabetes is an 
epidemic. There is never anything shared on TV about the signs and 
symptoms of T1 diabetes. Kids die from it after being misdiagnosed with 
strep throat or the flu. T1 diabetes mimics the flu. My son had strep 
throat when he was diagnosed. And it's not caused by vaccines. T1 
diabetes has been around for over 4500 years and no vaccines were 
invented then. People just died from it before insulin was invented in 
1921.

My personal story is this: I have epilepsy. I take 3 medications for 
it. One of them was invented in 1914. It's older than insulin. When my 
husband had a great job with great insurance, I paid $3.96 for a 90 day 
supply. When my husband lost his job, I was eligible to get on Medicare 
because I am on disability. When I went to get my medicine at the 
pharmacy, I was hit with a $114.41 bill. YIKES! This stuff is cheaper 
than aspirin and here I am paying $114.41. The Medicare system, the 
Part D, they put the medicine on the most expensive tier. So what am I 
supposed to do? I have to pay it or my head goes nuts. Another medicine 
I take, the patent doesn't expire until 2022, so there is no generic 
for it. I just had to pay $1,200.00 for this medicine at the beginning 
of the year. Ouch! My disability benefits are $1,600.00 a month. Do the 
math. I wish I had never started to take it. The next time I get the 
prescription filled, it will be $800.00 for it. I will never meet the 
deductible set on my Part D plan because it is set so high that I never 
reach it. So I pay over $300/year for my Part D plan, over 1,200.00/
year for my Part B, and even though the deductibles are lower than a 
high deductible plan like a Blue Cross plan, it still hurts the wallet 
every time I need to refill these prescriptions.

I'd like to share with you some stories of people that have children 
with T1 diabetes.

1. This lady had a child die from T1 diabetes after the girl was kicked 
off of BCMH at the age of 21. The girl rationed her insulin and was 
found dead at home. The lady also has a second daughter that has T1 
diabetes. She started a foundation and is on the warpath to make sure 
people don't die from insulin rationing and get kicked off of health 
plans. She just shared a story about her daughter being denied the 
Dexcom continuous glucose monitor. People like her are always fighting 
with insurance and distributors, especially Edgepark Medical Supply, to 
get their supplies. This is a problem created by insurance companies 
that ``don't want to pay.'' They will do everything in their power to 
deny you and now people are turning to Costco to get this Dexcom device 
and get out of the insurance loop to get it, and get it cheaper than it 
costs to use their insurance. Yet, these people are still paying their 
premiums and they can't use the insurance.

2. This lady and her son, they live in Tennessee. Tennessee, as I found 
out, is one of the states that did not adopt the Medicaid expansion. 
The son is 24 years old. He is a T1 diabetic as well. He was working at 
a Hardee's burger place. He lost his job after getting sick with 
diabeticketoacidosis (OKA). He was in the hospital and couldn't work so 
they fired him. He had no access to insulin and started taking the 
``WALMART'' insulin. This isn't the right kind of insulin for a T1 
diabetic to take. He ended up with a big sore on his arm from injecting 
the insulin in the same spot all the time. He ended up with a bad MRSA 
infection. He went to the hospital and was not taken care of very well 
and he checked himself out. He wanted something to drink and was denied 
water. The mother didn't know how to navigate the politics to get help 
in the state. She tried to get a social worker to get her son on 
Medicaid. She was told NO, that he didn't qualify because he wasn't 
pregnant, wasn't a single parent, and was over the age of 21.

So the message from the state of Tennessee is ``JUST GO DIE'' if you 
can't work and get private insurance and you're over the age of 21. 
``We don't want to take care of you anymore even though you have a life 
threatening disease.'' So I contacted the governor there and got his 
office to contact TennCare, the Medicaid office, and was able to at 
least get him set up to get insulin, but he still has no doctor to 
report to because he was denied care at a medical center there because 
he missed three appointments and they won't take him because of a long 
wait list. The option of moving out of the state is out of the question 
I was told. So here is a man that will end up living with his mother 
the rest of his life because he can't hold a job due to his diabetes.

3. A family from Texas. The father has a decent job but they live 
paycheck to paycheck. They also have a T1 diabetic child. The father 
was offered a TWENTY CENT raise. That means he would make $416.00 more 
per year. Guess what? The twenty cent raise put his family over the 
income qualifications to be able to continue to get CHIP benefits so 
they can afford the insulin for the diabetic. The family would be 
forced to take the insurance from the place of work. The insurance 
would cost them $400.00 per month out of their paycheck. That means 
they would lose $2.50 an hour if they took the twenty cent raise. Does 
that make sense to you? The father ended up signing a waiver and not 
accept the raise so he won't lose the CHIP benefits so he can keep his 
child alive and not have to go get another job or try to come up with 
the money for insulin one way or another? If insulin was affordable and 
accessible over the counter, the $416.00 a year raise might pay for it. 
But that's not the case. So much for a raise. I told the mother to tell 
the company to give him a gift card for $400.00 that she can use on 
groceries.

4. A United States citizen moved to the U.K. so she could get her 
insulin to stay alive. What in the world? Are you kidding me? Cases 
like this are what take money out of the U.S. economy.

5. A mother was on vacation, she only took one bottle of insulin with 
her. The insulin got dropped on the floor. She came running to Facebook 
to see if anyone could supply her with insulin because she couldn't get 
a hold of her doctor to see if she could get her prescription filled 
where she was. She couldn't just walk into any pharmacy and say she 
wanted to buy the insulin her child used. She could do that if she 
needed a bottle of water, but she can't do that with insulin. She was 
frantic, thinking, how am I going to keep my child alive? The 
pharmacist was not allowed to give her insulin without a prescription. 
There was no emergency system in place. The pharmacist had no 
authorization to give an emergency supply of insulin to this desperate 
mother. In the end, she was finally able to get her doctor to call her 
back and call in a prescription to the pharmacy to get a bottle of 
insulin. That should never happen in America.

So I see people pay for premiums out of their paychecks, they pay for 
copays at the doctor's office, they pay outrageous amounts of money in 
high deductibles, and what do they end up with? They end up in debt, 
end up with their own health problems because they are going crazy 
wondering where in the world they are going to get this money from and 
not have to lose everything they have.

Senator Stabenow was in a hearing that I watched and she actually said 
she took people over the border to Canada herself to get cheaper 
medicines. What does that tell you? That tells you that she's a great 
person that will do whatever she has to do to make sure people don't 
die at the hands of the current system. Our system is broken, it's old, 
it out of date, and I am not 100% sure if this is all because of the 
Affordable (Unaffordable) Care Act. I find that the people that make 
these laws are not the people that actually have children with life-
threatening diseases and they have no idea what the cost of managing 
the diseases consists of. If America is going to allow the 
pharmaceutical industry to dictate to them how the system should be 
run, then that is the wrong way of doing business.

I do think that the Senate Finance Committee and congress have to 
subpoena these other pharmaceutical CEOs and get them to answer and be 
transparent about how much it costs them to make their products. I have 
a change.org petition going around getting signatures to ask congress 
to subpoena them. You can't just invite them. An invitation can be 
ignored and turned down, but not a subpoena. Heather Bresch had to come 
to Washington to be transparent, so don't let the rest of them off the 
hook.

Another thing about Eli Lilly: I read in the news that they were going 
to buy an $8Billion oncology company. If they have $8B to buy an 
oncology company, then why are they killing people with the high costs 
of insulin, literally killing people because they just can't afford 
their outrageous prices? They should not be able to buy a company like 
that until insulin is affordable and accessible to everyone, not just 
in America, but even in Africa. Why isn't insulin available in Africa? 
People die from having no access to insulin there as well. Diabetes is 
a global disease. You can't eradicate it. There is a genetic component 
to it. People are living longer now with the invention of insulin so 
they are passing the genes along to their offspring who ultimately pass 
it on to the next generation.

March 5, 2019: This morning, as I continue to write and finish this, I 
see a news article about Senator Durbin's response to Eli Lilly's 
announcement yesterday. He acknowledges in there that insulin is as low 
as $38.00 in Canada, but charging Americans four times the amount of 
what Canadians pay it not an outpouring of gratitude. Canadians pay 
less because their government negotiates the prices with these insulin 
companies (http://www.kfvs12.com/2019/03/05/lawmaker-weighs-
annoucement-by-drug-maker-sell-lower-cost-insulin/). When will the 
United States do the same thing? Why do you have to have a National 
Health Care system to do it? Just regulate the industry, like gas and 
electric, and start setting limits on the prices they can charge. And 
the article says that Senator Durbin is urging the FDA to approve lower 
cost drugs. There is no generic insulin. Why, after almost 100 years, 
is there no generic insulin? Generic insulin is not the solution to 
this dilemma. Just lower the cost. They've made their money over the 
years, the patent for humalog is long since expired.

Like I said, Eli Lilly can just take humalog, stick it in a different 
bottle, relabel it, and tell you it's a generic. The FDA can't regulate 
prices. Let them be in charge of making sure drugs are safe, but don't 
leave them in charge of this. Mr. Gottlieb went and changed the 
category from a drug to a biologic--that didn't lower the price, it 
only created new patent s. If there was a regulated industry, the price 
would still be controlled on new patents.

Recap:

      The drug industry needs to be regulated. These companies need to 
be saved from themselves. They don't know how to do it on their own.

      Insulin needs to be available over the counter without a 
prescription. (Kevin's Law has been passed in many states to authorize 
pharmacies to give an emergency, up to 30 day, supply of insulin and 
the pharmacy and insurance can catch up with paperwork afterwards.)

      The United States needs to trust citizens to use insulin 
correctly. It's available over the counter in Mexico.

      The United States needs to find out exactly how much it costs to 
make insulin. The U.S. found out how much it costs to make an epipen.

      PBMs need to be abolished.

      High deductible healthcare plans need to be abolished.

      If insulin is not accessible over the counter without a 
prescription, then it should be exempt from any and all deductibles on 
healthcare plans, as should any prescription medications.

      No diabetic in America should be denied healthcare 
(#medicare4all).

      People shouldn't have to take out gofundme accounts to raise 
money for their medicines.

      People shouldn't have to take out home equity loans and second 
mortgages to pay for their medicines.

      People shouldn't have to turn to the black market and Facebook 
to find insulin.

      People shouldn't have to go out of the country to get affordable 
insulin (#insulin4all).

      People shouldn't have to share insulin with family members.

      People shouldn't have to revert to using the ``WALMART'' insulin 
which is going to kill them if not used correctly.

      People shouldn't have to rely on coupons and scrounge around for 
ways to get discounts on insulin and other drugs.

      People shouldn't have to feel they are a burden to their family 
and ration insulin.

      Companies that price gouge should be held accountable, fined and 
sued so they will stop being so greedy.

      CEOs shouldn't be making so much money while people are dying.

      Insurance companies shouldn't be able to dictate which medicines 
and insulin they want us to use. We should be able to choose the one 
that works for us. That's how the PBMs work. They tell us which insulin 
they will pay for. If insulin was available over the counter, the PBMs 
wouldn't be able to dictate which kind of insulin I want to use, just 
like they can't decide what kind of bread I want to eat or if I want to 
buy Mobil or Shell gasoline for my car.

      The Hatch-Waxman Act is being abused.

      The V.A. can negotiate prices for drugs and medical care, but 
only Medicare Parts A and B can negotiate prices. Medicare part D needs 
to be able to negotiate prices in an unregulated industry. You have the 
power, use it.

      Insulin doesn't need new R&D. Using that as a reason for high 
prices is a bad excuse for high prices.

      Television ads for prescription drugs has to stop, just as 
tobacco ads stopped.

      Politicians have to stop taking money from big pharmaceuticals. 
The pharmaceutical companies are like the mafia.

      If financial aid is going to remain available, the income 
requirements need to be adjusted to keep up with inflation and keep up 
with the times. People that make a decent, living wage, should be able 
to get some relief if these high deductible plans continue to exist. If 
you just got rid of high deductibles and the prices got lowered, we 
wouldn't be talking about this.

      Be proactive, not reactive. Right now we are in a reactive 
position.

      A sick person will always use the system since most want to 
live. Those that don't want to live will commit suicide.

      More teaching needs to take place in our country on what Type 1 
Diabetes really is. It is often mixed up with Type 2 diabetes. They are 
not the same disease.

      The PBMs need to be hired by the U.S. government to do the 
negotiating for lower prices, not be employees of the insurance 
companies. That creates a racket and secrets.

      Listen to more REAL stories of the burdens placed on Americans. 
Let the Americans tell you what they need and want, not allow the 
pharmaceutical companies to run their own agenda. Without sick people, 
they wouldn't even be in business.

      Put the brakes on big pharma.

      List prices work against the patient. Either set lower list 
prices or pass on the discounts to the patient.

      Patients don't care about pharmaceutical's position on the 
formularies, they care about being well.

      Stop the ``Happy Talk''; get down to business and pick up the 
pen (#thepowerofthepen).

      Lawmakers work for the citizens of the United States and get 
paid by our tax dollars. It's time for lawmakers to listen to citizens 
and not big pharma.

      Soriot's wise words: VBP--It used to be a system that was fit 
for purpose. Now it's no longer fit for purpose. No one in the system 
can fix it for themselves. The government has to step up and change the 
rules.

      #painpassionpurpose: Three words uttered to Nette Worsham by 
Congressman Cummings on January 29, 2019.

      CEOs from the two other insulin manufacturers, Eli Lilly and 
NovoNordisk need to be subpoenaed. They have been invited too many 
times and never accept the invite.

      Don't send letters asking for CEOs to tell you how much it costs 
them to make their drugs, make them come to Washington to tell you so 
the public can hear their lame excuses as well.

Thank you, and I look forward to the next showdown with the PBMs and 
insurance companies. They are part of the problem, not part of the 
solution. The United States government is the entity that is part of 
the solution.

Sincerely,

Laura T. Ricci
                      Statement of Rhonda Rowland

                         R2 Communications, LLC

                              Atlanta, GA

March 5, 2019

U.S. Senate
Committee on Finance
Dirksen Senate Office Bldg.
Washington, DC 20510-6200

To whom it may concern:

This is in reference to the ``Drug Pricing in America: A Prescription 
for Change, Part II'' hearing held on February 26, 2019.

As a person living with a rare disease and an advocate, I'm submitting 
the attached articles that provide background on the discovery/
development of two old, cheap drugs that pharma has raised prices on, 
and the impact on patients.

Best regards,

Rhonda Rowland
R2 Communications, LLC
[email protected]
RhondaRowland.com
404-680-9053

High drug costs: the tale of 4 women

In 2016, Berna Heyman testified before a U.S. Senate committee about 
her personal experience with sudden and dramatic increases in drug 
prices. She was forced to switch drugs to treat her chronic genetic 
disease, which was not the ideal option for her.

``The only reason I changed was the cost,'' Berna testified. Her health 
had been stable while taking the drug Syprine, which removes excess 
copper in people with Wilson disease (WD) to prevent potentially fatal 
poisoning. ``My doctor and I made the change only under duress.''

Valeant Pharmaceuticals (now Bausch Health) acquired the rights to 
Syprine in 2010 and began increasing the price. It's an old drug that 
was developed in the 1960s by British physician Dr. John Walshe, who 
made it in his laboratory and distributed it for free for many years. 
``It was cheap to make,'' he told me. The generic name for it is 
trientine.

As a librarian at the College of William and Mary in Virginia for 34 
years, Berna had good health insurance and drug coverage. Her WD went 
undiagnosed for 60 years, making her one of the oldest patients to be 
diagnosed. The first sign of her disease was cirrhosis of the liver 
that was picked up incidentally by a radiologist.

Upon retirement, she was insured through Medicare and supplementary 
insurance.

``By 2014 my projected co-pay exceeded $10,000 per year with my 
insurance paying over $260,000,'' Berna testified. ``That is untenable. 
Something has to be done.''

At the hearing, Valeant executives expressed regret and admitted to 
being too aggressive with their pricing strategies. When questioned by 
Senators, they said they'd lower their prices.

For 3 years, Berna has waited. But Bausch Health has yet to lower 
prices.

``I left the hearing feeling hopeful, and anticipated changes by 
Valeant,'' Berna told me. ``It's very disappointing. It's the same old, 
same old.''

Therapist kept patients out of the system, but drug company put her in 
                    it

Rose was completing her college degree in mechanical engineering when 
she noticed that she drooled while reading. Then she began forgetting 
math formulas, so she'd write them on her arm. As a straight-A student, 
she was bewildered that she had to re-read book chapters because she 
forgot what she'd read. She was on the crew team, but her fatigue got 
so bad that she couldn't keep up.

``I left college and went home,'' said Rose, who asked that her name be 
changed for privacy. After seeing more than a dozen doctors in New York 
and not getting a diagnosis, she went to an ophthalmologist who told 
her that some diseases can be diagnosed through the eye. He was right; 
an exam revealed Rose had rust-colored rings in her eyes, known as 
Kayser-Fleischer rings which are commonly seen in WD patients.

Once diagnosed, Rose began taking the de-coppering drug, penicillamine. 
Her condition improved and she returned to college. But her WD left her 
with some memory loss and she couldn't remember her calculus formulas. 
She switched majors and got a degree in occupational therapy.

Rose moved to Arizona and worked full-time as an occupational therapist 
for 20 years.

``Then one day I went to the pharmacy to pick up my WD drugs and was 
told my co-pay was $12,000! I was a single mom raising two kids and I 
couldn't afford it,'' said Rose. ``I felt totally screwed.''

She had been prescribed Cuprimine, the brand name version of 
penicillamine--also made by Bausch Health. Penicillamine was discovered 
in 1955, also by Dr. John Walshe. ``It's easy to make if you're a good 
chemist,'' Dr. Walshe told me.

Rose tried zinc supplements, an inexpensive, alternate treatment for 
WD, but they made her violently ill. Without her daily dose of 
Cuprimine, her fatigue returned and depression set in. She could only 
work part-time, so she lost her health insurance. Her WD symptoms 
worsened, so she could no longer work and applied for disability 
benefits.

``As an occupational therapist I was contributing to the system, and 
keeping others out of the system,'' said Rose. ``Then the drug company 
put me into the system.''

Importing drugs from Canada and overseas

After going without medication for months, Rose's uncle found a way for 
her to get affordable penicillamine through a Canadian pharmaceutical 
broker. At first, her supply came from England. ``The medicine looked 
and smelled like what I had taken for years, although the brands were 
different,'' said Rose. ``But then a shipment came from India that 
didn't smell right.''

She looked for another option and found Duane, a prescription drug 
broker in the Midwest who could get her drugs shipped directly from 
Australia. She needed a doctor's prescription and paid about $200 for a 
3-month supply.

``We operate in a loophole,'' Duane said. ``Individuals are allowed to 
bring in a three-month supply of prescription drugs from other 
countries.''

What Duane told me is partly true: It's illegal for individuals to 
import prescription drugs in most circumstances, because the FDA can't 
ensure the drugs' safety. And anyone who facilitates the importation is 
also liable. But in reality, the FDA looks the other way.

So, it's tempting to take the risk. Duane imports an AIDS medication 
for a client who had a $25,000 co-pay. ``I can get it for him for 
$1,200 a month.''

With exorbitant drug prices and patients' growing inability to pay 
them, there's momentum to make such drug imports legal. Five bills are 
before Congress that would allow prescription drug imports, primarily 
from Canada.

Staying at poverty level to get prescription drugs

Ashley Williams was about to start classes at Kansas State when she was 
diagnosed with WD and had to quit school to go to work instead. She was 
grateful to have a diagnosis for the hospitalizations and unnecessary 
surgeries she experienced the previous 2 years.

``I needed health insurance, so I took a full-time job with a 
technology company,'' said Ashley. ``I worked my way up from `coffee 
girl' to project manager and was working 70-80 hours a week.'' Even 
though she was taking Syprine, her health deteriorated. She thinks it 
was due to working too hard, to prove she wasn't sick.

For medical reasons she got laid off and applied for disability 
benefits. Now with Medicare and supplemental insurance to cover her 
health care, she can't afford her Syprine co-pays.

``This year, I was told that the funds for Wilson disease were already 
gone!'' said Ashley. ``The $1,200 co-pay for my 30 days of trientine 
took my entire Social Security check.''

``A health insurance broker advised me to look into the PAN 
Foundation,'' said Ashley. ``I qualified and get $10,000 a year to 
cover the cost of my co-pay.'' The Patient Access Network Foundation 
relies on donations to help people who are underinsured with medication 
costs.

Patients have to reapply every January for the PAN Foundation's drug 
benefit. ``But this year, I was told that the funds for Wilson disease 
were already gone!'' said Ashley. ``The $1,200 co-pay for my 30 days of 
trientine took my entire Social Security check.''

Teva Pharmaceuticals introduced the first generic trientine in 2018 to 
compete with Bausch's Syprine.

Generic competition hasn't lowered the drug cost . . . yet

Dawn, who was diagnosed with WD at age 37 after her liver failed, was 
shocked when she picked up her prescription for trientine in January. 
The list price was $38,365.09. Her insurance co-pay was only $15.

Still, she's not taking her good fortune for granted, and is 
stockpiling her drugs.

``I'm scared to take them all,'' said Dawn, who asked that her real 
name not be used. ``I went without my drugs for 3 years because we 
couldn't pay for them when the costs spiked.''

Ultimately, the drug saved her life. But they went bankrupt in the 
process.

Her husband had taken a new job just before she was diagnosed with WD. 
And then, just as their new insurance was coming through, ``the suckers 
fired him,'' Dawn says. ``They knew I needed a liver transplant and was 
really sick.''

She had no choice but to take Syprine, and ultimately, the drug saved 
her life. But they went bankrupt in the process.

Bausch currently offers patient assistance programs to insured and 
uninsured WD patients in the US who need Syprine or Cuprimine. ``Our 
first priority is that every patient has access to the medicines they 
need,'' a Bausch Health spokesperson said in a statement.

Dawn tried to get help from the drug company previously, but couldn't. 
The inexpensive alternative, zinc therapy, made her sick.

Her husband eventually found a job that provided health insurance--700 
miles from their home, in another state. ``He works 70 hours a week 
hauling chemicals in extreme weather on treacherous roads. It aged him 
so much.''

Dawn's liver healed enough so she could be taken off the transplant 
list. Still, she's furious with the drug company for making the drug's 
cost out of reach for 3 years. And, she's fearful it could happen 
again.

How does the tale end for the 4 women?

Berna Heyman is encouraged that the problem of high drugs costs is 
still a major discussion. ``That's the bright side,'' she said.

However, since she was forced to switch her WD medication, tests show 
copper has reaccumulated in her liver. Her doctor advised a low-copper 
diet for several months, but that didn't help. ``I may have to start 
taking trientine again.''

Rose credits Duane for saving her life with the drug imports. But fear 
of her supply line drying up led her to enroll in a clinical trial 
testing a new drug for Wilson disease so she can get her life-saving 
medication at no cost for the next five years. ``I hope the new drug 
works,'' she said.

Fear over the uncertainty of being able to pay for her drugs also led 
Ashley Williams to enroll in the new WD drug trial. By chance, she was 
put in the ``standard of care'' arm of the trial. That means she 
continued on trientine for a year and paid the drug's cost. ``Starting 
in April, I will be taking the new study drug,'' she said. That means 
she pays the $1,200 co-pay for her trientine for another month.

``It's scary to think that I have to stay in a drug trial to get my 
medication paid for,'' Ashley said.

Even though Syprine saved Dawn's life, she's fearful that the drug's 
cost could make it out of reach for her again. Her solution: Rationing 
her drugs.

Perhaps this will be the year that the Wilson disease drugs Dr. John 
Walshe discovered and developed more than 50 years ago will be 
affordable again. But, the human toll and cost to society that the 
drugs' price spikes caused, remains.

                                 ______
                                 

98-year-old drug inventor chastises pharma for ``behaving badly''

I've spent my career reporting medical news. It's an important topic to 
me because I live with my own health challenge: A rare, genetic 
condition called Wilson disease that allows copper--an essential 
dietary mineral--to build up in the liver and brain, leading to copper 
poisoning that can be fatal. It caused my liver to fail when I was a 
college student. But I was lucky--I was diagnosed, there was a 
treatment, and it worked.

Before 1955, my disease was fatal. Then, through a series of chance 
events and serendipities, an English physician, Dr. John Walshe, 
discovered a drug that turned Wilson disease (WD) into one that could 
be treated and managed. The drug is known by its generic name, 
penicillamine, and the brand names, Cuprimine and Depen.

While doing research for a book I'm writing on WD, I discovered that 
Dr. Walshe is still very much alive and well at age 98. So I traveled 
to Cambridge, England to thank him for saving my life and talk to him 
about his drug discovery.

He invited me to his home, which is a William and Mary style house 
built in the late 1600s, in the riverside village of Hemingford Grey, 
near Cambridge. Talking in Dr. Walshe's quintessential English garden, 
it didn't take him long to attack the pharmaceutical industry that now 
sells the drug that he discovered and tested.

``The way they're charging for it now is absolutely immoral. There is 
no other word for it,'' Dr. Walshe told me. ``It is totally immoral. It 
is business at its worst!''

For more than 20 years I took Cuprimine and never paid more than $60 a 
month for it. Today, it costs $31,426 a month making it the 13th most 
expensive prescription drug in 2018.

Discovering the first treatment for Wilson disease

Listening to the story of Dr. Walshe's drug discovery, it's easy to 
understand why he's incredulous about its cost.

The story began in 1954, when Dr. Walshe traveled to the United States 
for a Fulbright Fellowship in Boston. ``I was working with Charlie 
Davidson who was a liver doctor, and we were asked to see a Wilson 
disease patient who had gone into liver failure,'' said Dr. Walshe.

They couldn't do anything to help the patient then, but crossing the 
``bridge'' from what was then Boston City Hospital where the patient 
was being cared for, back to Thorndike Laboratory where he worked, Dr. 
Walshe had what he calls as inspiration: ``I said to Charlie Davidson, 
`You know what this chap really needs is penicillamine.' And Charlie 
Davidson said `What's that?' I told him I discovered this new amino 
acid that had never been seen in human urine before,'' said Dr. Walshe.

Previously, while working in London during the early 1950s, Dr. Walshe 
had studied laboratory samples from people who were given the 
antibiotic penicillin. He observed that penicillamine--a derivative of 
penicillin--binds with copper. It's a process called chelation. His 
theory was that penicillamine could search out the excess copper in 
people with Wilson disease, bind with it, and then remove it from the 
body through urination.

Proving his idea

To test his theory, Dr. Walshe obtained some penicillamine from a 
chemist at MIT. Then, he did what would be unheard of today--he tried 
it on himself first. ``It didn't do me any harm and the next day I was 
alive and well,'' he said. ``I decided if it was safe for me, it was 
safe for the patient.''

Dr. Walshe gave penicillamine to the WD patient--who was in liver 
failure at Boston City Hospital--and as he predicted, it got copper 
out. When his fellowship in Boston ended, he returned to London with a 
small supply of penicillamine to continue his experiments there.

``My father was England's leading neurologist at the time, and I asked 
him to find some Wilson disease patients for me to try it out on,'' 
said Dr. Walshe. His father came through with a handful of patients, 
and in 1956 Dr. Walshe reported in the American Journal of Medicine 
that his drug discovery worked.

After that, Dr. Walshe searched for chemical companies willing to make 
penicillamine so the new treatment could be made available to WD 
patients as soon as possible. This was years before the start of the 
current FDA drug approval process that requires costly and extensive 
testing before a drug can be considered for marketing.

Developing an alternative

As word spread that there was a treatment for Wilson disease, doctors 
started prescribing penicillamine for their patients. However, as more 
patients took it, they found that some developed severe side effects. 
So, Dr. Walshe looked for a second option.

``We had run into trouble with penicillamine, and I wanted an 
alternative treatment,'' said Dr. Walshe.

By this time he was working at the University of Cambridge, and one 
morning he ran into a biochemist named Dr. Hal Dixon. Dr. Walshe 
explained his predicament, and Dr. Dixon pulled a chemical called 
triethylene tetramine off his laboratory shelf.

``He said it was non-toxic and known to bind with copper,'' said Dr. 
Walshe. ``He told me to try it, and that's how we got the drug 
trientine. It was Hal Dixon's idea, and my work proving that it worked 
and it was safe.''

Walshe made the drug himself

For years, Dr. Walshe and his assistant made trientine in their 
laboratory until they could no longer keep up with demand.Dr. Dixon had 
explained how to purify the chemical so it would be safe to use in 
people. So, as he had done with penicillamine, Dr. Walshe searched for 
a chemical company to make and distribute trientine. In 1985, trientine 
became the fifth drug approved through the Orphan Drug Act.

``The trouble now is the people who make trientine behave so badly 
about pricing,'' said Dr. Walshe. ``No doubt about it, they have 
behaved appallingly badly about pricing.''

Univar Europe charges the UK's National Health Service the equivalent 
of $96,000 to treat a patient for a year. Because of the high cost, the 
NHS debated whether or not it could continue paying for the drug in 
2019. The North American company Valeant Pharmaceuticals--now Bausch 
Health--charges even more for its brand-name version, Syprine.

Investigating high drug costs

In 2016, Senator Susan Collins (R-Maine) launched a bipartisan 
investigation into the extreme spikes that were being seen in drugs 
that were off-patent. ``For example, the price of a Valeant drug that 
is used to treat Wilson disease,'' said Collins, ``increased from $652 
per month to more than $21,000 per month. That's more than a 3,000 
percent increase in price with no justification.''

``It's monstrous, it's iniquitous what they're charging for it,'' said 
Dr. Walshe. For several years he made trientine in his laboratory. ``I 
sent it out for free on my basic laboratory expense allowance without 
upsetting it. It was cheap!''

In the United States, Bausch Health now markets Syprine (the brand-name 
version of trientine) as well as Cuprimine.The company acquired both 
drugs in 2010 and, soon after, boosted the prices astronomically. 
Despite extensive adverse publicity, a Congressional hearing, and the 
addition of generic equivalents the company has yet to lower the drugs' 
unjustified cost.

Walshe never profited from his drug discoveries

It's been almost 65 years since Dr. John Walshe had his ``inspiration'' 
while walking across the bridge at Harvard. I asked him where the idea 
came from. He simply pointed to the sky and posed the rhetorical 
question: ``Where do ideas come from?''

Dr. Walshe's discovery of penicillamine and the development of 
trientine turned Wilson disease from a death sentence into a treatable 
disease. Today, the challenge for patients is not finding treatment, 
but being able to pay for it. Dr. Walshe says he never made any money 
from the two drugs, instead devoting his medical career to helping 
people with WD.

His idea saved my life. Now with the prices being charged for his 
discoveries, will others be so lucky?