[Title 40 CFR 720]
[Code of Federal Regulations (annual edition) - July 1, 1999 Edition]
[Title 40 - PROTECTION OF ENVIRONMENT]
[Chapter I - ENVIRONMENTAL PROTECTION AGENCY (CONTINUED)]
[Subchapter R - TOXIC SUBSTANCES CONTROL ACT]
[Part 720 - PREMANUFACTURE NOTIFICATION]
[From the U.S. Government Printing Office]


40PROTECTION OF ENVIRONMENT231999-07-011999-07-01falsePREMANUFACTURE NOTIFICATION720PART 720PROTECTION OF ENVIRONMENTENVIRONMENTAL PROTECTION AGENCY (CONTINUED)TOXIC SUBSTANCES CONTROL ACT
PART 720--PREMANUFACTURE NOTIFICATION--Table of Contents




                      Subpart A--General Provisions

Sec.
720.1  Scope.
720.3  Definitions.

                        Subpart B--Applicability

720.22  Persons who must report.
720.25  Determining whether a chemical substance is on the Inventory.
720.30  Chemicals not subject to notification requirements.
720.36  Exemption for research and development.
720.38  Exemptions for test marketing.

                         Subpart C--Notice Form

720.40  General.
720.45  Information that must be included in the notice form.
720.50  Submission of test data and other data concerning the health and 
          environmental effects of a substance.
720.57  Imports.

                    Subpart D--Disposition of Notices

720.60  General.
720.62  Notice that notification is not required.
720.65  Acknowledgment of receipt of a notice; errors in the notice; 
          incomplete submissions; false and misleading statements.
720.70  Notice in the Federal Register.
720.75  Notice review period.
720.78  Recordkeeping.

       Subpart E--Confidentiality and Public Access to Information

720.80  General provisions.
720.85  Chemical identity.
720.87  Categories or proposed categories of uses of a new chemical 
          substance.
720.90  Data from health and safety studies.
720.95  Public file.

            Subpart F--Commencement of Manufacture or Import

720.102  Notice of commencement of manufacture or import.

                  Subpart G--Compliance and Inspections

720.120  Compliance.
720.122  Inspections.

    Authority: 15 U.S.C. 2604, 2607, and 2613.

    Source: 48 FR 21742, May 13, 1983, unless otherwise noted.

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                      Subpart A--General Provisions



Sec. 720.1  Scope.

    This part establishes procedures for the reporting of new chemical 
substances by manufacturers and importers under section 5 of the Toxic 
Substances Control Act, 15 U.S.C. 2604. This part applies to 
microorganisms only to the extent provided by part 725 of this chapter. 
The rule defines the persons and chemical substances subject to the 
reporting requirements, prescribes the contents of section 5 notices, 
and establishes procedures for submitting notices. The rule also 
establishes EPA policy regarding claims of confidentiality for, and 
public disclosure of, various categories of information submitted in 
connection with section 5 notices.

[48 FR 21742, May 13, 1983, as amended at 58 FR 34204, June 23, 1993; 62 
FR 17932, April 11, 1997]



Sec. 720.3  Definitions.

    (a)(1) For the purposes of this part, the terms cosmetic, device, 
drug, food, and food additive have the meanings contained in the Federal 
Food, Drug, and Cosmetic Act, 21 U.S.C. 321 et seq., and the regulations 
issued under it. In addition, the term ``food'' includes poultry and 
poultry products, as defined in the Poultry Products Inspection Act, 21 
U.S.C. 453 et seq.; meats and meat food products, as defined in the 
Federal Meat Inspection Act, 21 U.S.C. 60 et seq.; and eggs and egg 
products, as defined in the Egg Products Inspection Act, 21 U.S.C. 1033 
et seq.
    (2) The term pesticide has the meaning contained in the Federal 
Insecticide, Fungicide, and Rodenticide Act, 7 U.S.C. 136 et seq. and 
the regulations issued under it.
    (3) The terms byproduct material, source material, and special 
nuclear material have the meanings contained in the Atomic Energy Act of 
1954, 42 U.S.C 2014 et seq. and the regulations issued under it.
    (b) Act means the Toxic Substances Control Act, 15 U.S.C. 2601 et 
seq.
    (c) Article means a manufactured item (1) which is formed to a 
specific shape or design during manufacture, (2) which has end use 
function(s) dependent in whole or in part upon its shape or design 
during end use, and (3) which has either no change of chemical 
composition during its end use or only those changes of composition 
which have no commercial purpose separate from that of the article and 
that may occur as described in Sec. 720.36(g)(5), except that fluids and 
particles are not considered articles regardless of shape or design.
    (d) Byproduct means a chemical substance produced without a separate 
commercial intent during the manufacture, processing, use, or disposal 
of another chemical substance or mixture.
    (e) Chemical substance means any organic or inorganic substance of a 
particular molecular identity, including any combination of such 
substances occurring in whole or in part as a result of a chemical 
reaction or occurring in nature, and any chemical element or uncombined 
radical, except that ``chemical substance'' does not include:
    (1) Any mixture.
    (2) Any pesticide when manufactured, processed, or distributed in 
commerce for use as a pesticide.
    (3) Tobacco or any tobacco product.
    (4) Any source material, special nuclear material, or byproduct 
material.
    (5) Any pistol, firearm, revolver, shells, or cartridges.
    (6) Any food, food additive, drug, cosmetic, or device, when 
manufactured, processed, or distributed in commerce for use as a food, 
food additive, drug, cosmetic, or device.
    (f) Commerce means trade, traffic, transportation, or other commerce 
(1) between a place in a State and any place outside of such State, or 
(2) which affects trade, traffic, transportation, or commerce between a 
place in a State and any place outside of such State.
    (g) Customs territory of the United States means the 50 States, 
Puerto Rico, and the District of Columbia.
    (h) Director means the Director of the EPA Office of Pollution 
Prevention and Toxics.
    (i) Distribute in commerce means to sell in commerce, to introduce 
or deliver for introduction into commerce, or to hold after introduction 
into commerce.
    (j) EPA means the U.S. Environmental Protection Agency.

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    (k) Health and safety study or study means any study of any effect 
of a chemical substance or mixture on health or the environment or on 
both, including underlying data and epidemiological studies, studies of 
occupational exposure to a chemical substance or mixture, toxicological, 
clinical, and ecological, or other studies of a chemical substance or 
mixture, and any test performed under the Act. Chemical identity is 
always part of a health and safety study.
    (1) Not only is information which arises as a result of a formal, 
disciplined study included, but other information relating to the 
effects of a chemical substance or mixture on health or the environment 
is also included. Any data that bear on the effects of a chemical 
substance on health or the environment would be included.
    (2) Examples include:
    (i) Long- and short-term tests of mutagenicity, carcinogenicity, or 
teratogenicity; data on behavioral disorders; dermatoxicity; 
pharmacological effects; mammalian absorption, distribution, metabolism, 
and excretion; cumulative, additive, and synergistic effects; acute, 
subchronic, and chronic effects; and structure/activity analyses.
    (ii) Tests for ecological or other environmental effects on 
invertebrates, fish, or other animals, and plants, including: Acute 
toxicity tests, chronic toxicity tests, critical life stage tests, 
behavioral tests, algal growth tests, seed germination tests, plant 
growth or damage tests, microbial function tests, bioconcentration or 
bioaccumulation tests, and model ecosystem (microcosm) studies.
    (iii) Assessments of human and environmental exposure, including 
workplace exposure, and impacts of a particular chemical substance or 
mixture on the environment, including surveys, tests, and studies of: 
Biological, photochemical, and chemical degradation; air, water, and 
soil transport; biomagnification and bioconcentration; and chemical and 
physical properties, e.g., boiling point, vapor pressure, evaporation 
rates from soil and water, octanol/water partition coefficient, and 
water solubility.
    (iv) Monitoring data, when they have been aggregated and analyzed to 
measure the exposure of humans or the environment to a chemical 
substance or mixture.
    (v) Any assessments of risk to health and the environment resulting 
from the manufacture, processing, distribution in commerce, use, or 
disposal of the chemical substance.
    (l) Importer means any person who imports a chemical substance, 
including a chemical substance as part of a mixture or article, into the 
customs territory of the United States. ``Importer'' includes the person 
primarily liable for the payment of any duties on the merchandise or an 
authorized agent acting on his or her behalf. The term also includes, as 
appropriate:
    (1) The consignee.
    (2) The importer of record.
    (3) The actual owner if an actual owner's declaration and 
superseding bond has been filed in accordance with 19 CFR 141.20; or
    (4) The transferee, if the right to draw merchandise in a bonded 
warehouse has been transferred in accordance with subpart C of 19 CFR 
part 144. (See ``principal importer.'')
    (m) Impurity means a chemical substance which is unintentionally 
present with another chemical substance.
    (n) Intermediate means any chemical substance that is consumed, in 
whole or in part, in chemical reactions used for the intentional 
manufacture of another chemical substance(s) or mixture(s), or that is 
intentionally present for the purpose of altering the rates of such 
chemical reactions.
    (o) Inventory means the list of chemical substances manufactured or 
processed in the United States that EPA compiled and keeps current under 
section 8(b) of the Act.
    (p) Known to or reasonably ascertainable by means all information in 
a person's possession or control, plus all information that a reasonable 
person similarly situated might be expected to possess, control, or 
know.
    (q) Manufacture means to produce or manufacture in the United States 
or import into the customs territory of the United States.
    (r) Manufacture or import for commercial purposes means:
    (1) To import, produce, or manufacture with the purpose of obtaining 
an

[[Page 97]]

immediate or eventual commercial advantage for the manufacturer or 
importer, and includes, among other things, ``manufacture'' of any 
amount of a chemical substance or mixture:
    (i) For commercial distribution, including for test marketing.
    (ii) For use by the manufacturer, including use for product research 
and development or as an intermediate.
    (2) The term also applies to substances that are produced 
coincidentally during the manufacture, processing, use, or disposal of 
another substance or mixture, including byproducts that are separated 
from that other substance or mixture and impurities that remain in that 
substance or mixture. Byproducts and impurities without separate 
commercial value are nonetheless produced for the purpose of obtaining a 
commercial advantage, since they are part of the manufacture of a 
chemical substance for commercial purposes.
    (s) Manufacture solely for export means to manufacture or import for 
commercial purposes a chemical substance solely for export from the 
United States under the following restrictions on activities in the 
United States:
    (1) Distribution in commerce is limited to purposes of export or 
processing solely for export as defined in Sec. 721.3 of this chapter.
    (2) The manufacturer or importer, and any person to whom the 
substance is distributed for purposes of export or processing solely for 
export (as defined in Sec. 721.3 of this chapter), may not use the 
substance except in small quantities solely for research and development 
in accordance with Sec. 720.36.
    (t) Manufacturer means a person who imports, produces, or 
manufactures a chemical substance. A person who extracts a component 
chemical substance from a previously existing chemical substance or a 
complex combination of substances is a manufacturer of that component 
chemical substance. A person who contracts with a manufacturer to 
manufacture or produce a chemical substance is also a manufacturer if 
(1) the manufacturer manufactures or produces the substance exclusively 
for that person, and (2) that person specifies the identity of the 
substance and controls the total amount produced and the basic 
technology for the plant process.
    (u) Mixture means any combination of two or more chemical substances 
if the combination does not occur in nature and is not, in whole or in 
part, the result of a chemical reaction; except ``mixture'' does include 
(1) any combination which occurs, in whole or in part, as a result of a 
chemical reaction if the combination could have been manufactured for 
commercial purposes without a chemical reaction at the time the chemical 
substances comprising the combination were combined, and if all of the 
chemical substances comprising the combination are not new chemical 
substances, and (2) hydrates of a chemical substance or hydrated ions 
formed by association of a chemical substance with water, so long as the 
nonhydrated form is itself not a new chemical substance.
    (v) New chemical substance means any chemical substance which is not 
included on the Inventory.
    (w) Nonisolated intermediate means any intermediate that is not 
intentionally removed from the equipment in which it is manufactured, 
including the reaction vessel in which it is manufactured, equipment 
which is ancillary to the reaction vessel, and any equipment through 
which the chemical substance passes during a continuous flow process, 
but not including tanks or other vessels in which the substance is 
stored after its manufacture.
    (x) Person means any natural person, firm, company, corporation, 
joint-venture, partnership, sole proprietorship, association, or any 
other business entity, any State or political subdivision thereof, any 
municipality, any interstate body, and any department, agency or 
instrumentality of the Federal Government.
    (y) Possession or control means in possession or control of the 
submitter, or of any subsidiary, partnership in which the submitter is a 
general partner, parent company, or any company or partnership which the 
parent company owns or controls, if the subsidiary, parent company, or 
other company or partnership is associated with the submitter in the 
research, development,

[[Page 98]]

test marketing, or commercial marketing of the chemical substance in 
question. (A parent company owns or controls another company if the 
parent owns or controls 50 percent or more of the other company's voting 
stock. A parent company owns or controls any partnership in which it is 
a general partner). Information is included within this definition if it 
is:
    (1) In files maintained by submitter's employees who are:
    (i) Associated with research, development, test marketing, or 
commercial marketing of the chemical substance in question.
    (ii) Reasonably likely to have such data.
    (2) Maintained in the files of other agents of the submitter who are 
associated with research, development, test marketing, or commercial 
marketing of the chemical substance in question in the course of their 
employment as such agents.
    (z) Principal importer means the first importer who, knowing that a 
new chemical substance will be imported rather than manufactured 
domestically, specifies the identity of the chemical substance and the 
total amount to be imported. Only persons who are incorporated, 
licensed, or doing business in the United States may be principal 
importers.
    (aa) Process means the preparation of a chemical substance or 
mixture, after its manufacture, for distribution in commerce (1) in the 
same form or physical state as, or in a different form or physical state 
from, that in which it was received by the person so preparing such 
substance or mixture, or (2) as part of a mixture or article containing 
the chemical substance or mixture.
    (bb) Processor means any person who processes a chemical substance 
or mixture.
    (cc) Small quantities solely for research and development (or 
``small quantities solely for purposes of scientific experimentation or 
analysis or chemical research on, or analysis of, such substance or 
another substance, including such research or analysis for the 
development of a product'') means quantities of a chemical substance 
manufactured, imported, or processed or proposed to be manufactured, 
imported, or processed solely for research and development that are not 
greater than reasonably necessary for such purposes.
    (dd) State means any State of the United States and the District of 
Columbia, the Commonwealth of Puerto Rico, the Virgin Islands, Guam, the 
Canal Zone, American Samoa, the Northern Mariana Islands, and any other 
territory or possession of the United States.
    (ee) Technically qualified individual means a person or persons (1) 
who, because of education, training, or experience, or a combination of 
these factors, is capable of understanding the health and environmental 
risks associated with the chemical substance which is used under his or 
her supervision, (2) who is responsible for enforcing appropriate 
methods of conducting scientific experimentation, analysis, or chemical 
research to minimize such risks, and (3) who is responsible for the 
safety assessments and clearances related to the procurement, storage, 
use, and disposal of the chemical substance as may be appropriate or 
required within the scope of conducting a research and development 
activity.
    (ff) Test data means data from a formal or informal test or 
experiment, including information concerning the objectives, 
experimental methods and materials, protocols, results, data analyses, 
recorded observations, monitoring data, measurements, and conclusions 
from a test or experiment.
    (gg) Test marketing means the distribution in commerce of no more 
than a predetermined amount of a chemical substance, mixture, or article 
containing that chemical substance or mixture, by a manufacturer or 
processor, to no more than a defined number of potential customers to 
explore market capability in a competitive situation during a 
predetermined testing period prior to the broader distribution of that 
chemical substance, mixture, or article in commerce.
    (hh) United States, when used in the geographic sense, means all of 
the States.

[48 FR 21742, May 13, 1983, as amended at 51 FR 15101, Apr. 22, 1986]

[[Page 99]]



                        Subpart B--Applicability



Sec. 720.22  Persons who must report.

    (a)(1) Any person who intends to manufacture a new chemical 
substance in the United States for commercial purposes must submit a 
notice unless the substance is excluded under Sec. 720.30.
    (2) If a person contracts with a manufacturer to manufacture or 
produce a new chemical substance, and (i) the manufacturer manufactures 
or produces the substance exclusively for that person, and (ii) that 
person specifies the identity of the substance, and controls the total 
amount produced and the basic technology for the plant process, that 
person must submit the notice. If it is unclear who must report, EPA 
should be contacted to determine who must submit the notice.
    (3) Only manufacturers that are incorporated, licensed, or doing 
business in the United States may submit a notice.
    (b)(1) Any person who intends to import a new chemical substance 
into the United States for commercial purposes must submit a notice, 
unless the substance is excluded under Sec. 720.30 or unless the 
substance is imported as part of an article.
    (2) When several persons are involved in an import transaction, the 
notice must be submitted by the principal importer. If no one person 
fits the principal importer definition in a particular transaction, the 
importer should contact EPA to determine who must submit the notice for 
that transaction.



Sec. 720.25  Determining whether a chemical substance is on the Inventory.

    (a) A new chemical substance is any chemical substance that is not 
currently listed on the Inventory.
    (b)(1) A chemical substance is listed in the public portion of the 
Inventory by a specific chemical name (either a Chemical Abstracts (CA) 
Index Name or a CA Preferred Name) and a Chemical Abstracts Service 
(CAS) Registry Number if its identity is not confidential. If its 
identity is confidential, it is listed in the public portion of the 
Inventory by a TSCA Accession Number and a generic chemical name that 
masks the specific substance identity. The confidential substance is 
listed by its specific chemical name only in the confidential portion of 
the Inventory, which is not available to the public. A person who 
intends to manufacture or import a chemical substance not listed by 
specific chemical name in the public portion of the Inventory may ask 
EPA whether the substance is included in the confidential Inventory. EPA 
will answer such an inquiry only if EPA determines that the person has a 
bona fide intent to manufacture or import the chemical substance for 
commercial purposes.
    (2) To establish a bona fide intent to manufacture or import a 
chemical substance, the person who proposes to manufacture or import the 
substance must submit to EPA:
    (i) Except as provided in paragraphs (b)(3) (i) and (ii) of this 
section, the specific chemical identity of the substance that the person 
intends to manufacture or import, using the currently, correct CA name 
for the substance and the other correct chemical identity information in 
accordance with Secs. 720.45(a) (1), (2), and (3).
    (ii) A signed statement that the person intends to manufacture or 
import that chemical substance for commercial purposes.
    (iii)(A) A brief description of the research and development 
activities conducted to date related to the substance, including the 
year in which the person first started to conduct research or 
development activity on the substance, and the general types of research 
and development activities conducted thus far (e.g., synthesis, 
substance isolation/purification, formulating, product development, 
process development, end-use application, toxicity testing, etc.). The 
person must also indicate whether any pilot plant or production-scale 
plant evaluations have been conducted involving the manufacture or 
processing of the substance.
    (B) If an importer is unable to provide the information requested in 
paragraph (b)(2)(iii)(A) of this section from the foreign manufacturer 
or supplier, the following information shall be submitted:

[[Page 100]]

    (1) A brief statement indicating how long the substance has been in 
commercial use outside of the United States.
    (2) The name of a country in which it has been commercially used.
    (3) Whether the importer believes that the substance has already 
been used commercially, in any country, for the same purpose or 
application that the importer is intending.
    (iv) A specific description of the major intended application or use 
of the substance.
    (v) An infrared spectrum of the substance, or alternative spectra or 
other data which identify the substance if infrared analysis is not 
suitable for the substance or does not yield a reasonable amount of 
structural information. When using alternative spectra or instrumental 
analysis, the person must submit a spectrum or instrumental readout for 
the substance.
    (vi) The estimated date (month/year) in which the person intends to 
submit a Premanufacture Notice (PMN) for this substance if EPA informs 
the notice submitter that the substance is not on the Inventory.
    (vii) The address of the facility under the control of the submitter 
at which the manufacture or processing of the substance would most 
likely occur. For an imported substance, the facility under the control 
of the importer at which processing of the substance would likely occur, 
if any.
    (viii)(A) For substances intended to be manufactured in the United 
States, a description of the most probable manufacturing process that 
would be used by the submitter to produce the substance for non-exempt 
commercial purposes.
    (B) For substances intended to be imported, a brief description of 
how the submitter is most likely to process or use the substance for a 
commercial purpose. If the substance is not expected to be processed or 
used at any facility under the importer's control, a statement to this 
effect must be included along with a description of how the substance 
will be processed or used at sites controlled by others, if this 
information is known or reasonably ascertainable.
    (3)(i) If an importer cannot provide the chemical identity 
information required by paragraph (b)(2) (i) and (v) of this section 
because it is claimed confidential by its foreign manufacturer or 
supplier, the foreign manufacturer or supplier must supply the required 
information directly to EPA in accordance with Sec. 720.45(a) (1), (2), 
and (3) and reference the importer's notice. If the appropriate 
supporting document from the foreign party is not received within 30 
days after EPA receives the importer's notice, the notice will be 
considered incomplete.
    (ii) If a manufacturer cannot provide all of the required 
information in accordance with Sec. 720.45(a) (1), (2), and (3) because 
the new chemical substance is manufactured using a reactant that has a 
specific chemical identity claimed as confidential by its supplier, the 
notice must contain chemical identity information that is as complete as 
known by the manufacturer. In addition, a letter of support for the 
notice must then be sent to EPA by the chemical supplier of the 
confidential reactant, providing the specific chemical identity of the 
proprietary reactant. The letter of support must reference the 
manufacturer's notice. If the appropriate supporting document from the 
supplier is not received within 30 days after EPA receives the 
manufacturer's notice, the notice will be considered incomplete.
    (4) EPA will review the information submitted by the proposed 
manufacturer or importer under this paragraph to determine whether it 
has a bona fide intent to manufacture or import the chemical substance. 
If necessary, EPA will compare this information either to the 
information requested for the confidential chemical substance under 
Sec. 710.7(e)(2)(v) of this chapter or the information requested under 
Sec. 720.85(b)(3)(iii).
    (5) If the proposed manufacturer or importer has shown a bona fide 
intent to manufacture or import the substance, and provide sufficient 
unambiguous chemical identity information so

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EPA can make a conclusive determination of the chemical substance's 
Inventory status, EPA will search the confidential Inventory and inform 
the proposed manufacturer or importer whether the chemical substance is 
on the confidential Inventory.
    (6) If the chemical substance is found on the confidential 
Inventory, EPA will notify the person(s) who originally reported the 
chemical substance that another person has demonstrated a bona fide 
intent to manufacture or import the substance and therefore was told 
that the chemical substance is on the Inventory.
    (7) A disclosure of a confidential chemical identity to a person 
with a bona fide intent to manufacture or import the particular chemical 
substance will not be considered a public disclosure of confidential 
business information under section 14 of the Act.
    (8) EPA will answer an inquiry on whether a particular chemical 
substance is on the confidential Inventory within 30 days after receipt 
of a complete submission under paragraph (b)(2) of this section.
    (9) If the required chemical identity information has not been 
reported correctly or completely in the notice (except as provided under 
paragraph (b)(3)(ii) of this section) or if any other required data or 
information has been omitted or is incomplete, EPA will consider the 
whole notice to be incomplete. As soon as an incomplete notice is 
identified as such by EPA, the Agency will immediately return the notice 
directly to the submitter. The submitter must then resubmit the whole, 
completed bona fide notice to EPA in order to have the Agency perform 
the desired Inventory search and respond to the notice.

[48 FR 21742, May 13, 1983, as amended at 58 FR 34204, June 23, 1993; 60 
FR 16309, Mar. 29, 1995]



Sec. 720.30  Chemicals not subject to notification requirements.

    The following substances are not subject to the notification 
requirements of this part:
    (a) Any substance which is not a ``chemical substance'' as defined 
in Sec. 720.3(e).
    (b) Any mixture as defined in Sec. 720.3(u).1
---------------------------------------------------------------------------

    \1\ A new chemical substance that is manufactured or imported as 
part of a mixture is subject to the requirements of this part. This 
exclusion applies only to a mixture as a whole and not to any chemical 
substances which are part of the mixture.
---------------------------------------------------------------------------

    (c) Any new chemical substance which will be manufactured or 
imported in small quantities solely for research and development under 
Sec. 720.36.
    (d) Any new chemical substance which will be manufactured or 
imported solely for test-marketing purposes under an exemption granted 
under Sec. 720.38.
    (e) Any new chemical substance manufactured solely for export if, 
when the substance is distributed in commerce:
    (1) The substance is labeled in accordance with section 12(a)(1)(B) 
of the Act.
    (2) The manufacturer knows that the person to whom the substance is 
being distributed intends to export it or process it solely for export 
as defined in Sec. 721.3 of this chapter.
    (f) Any new chemical substance which is manufactured or imported 
under the terms of a rule promulgated under section 5(h)(4) of the Act.
    (g) Any byproduct if its only commercial purpose is for use by 
public or private organizations that (1) burn it as a fuel, (2) dispose 
of it as a waste, including in a landfill or for enriching soil, or (3) 
extract component chemical substances from it for commercial purposes. 
(This exclusion only applies to the byproduct; it does not apply to the 
component substances extracted from the byproduct.)
    (h) The chemical substances described below: (Although they are 
manufactured for commercial purposes under the Act, they are not 
manufactured for distribution in commerce as chemical substances per se 
and have no commercial purpose separate from the substance, mixture, or 
article of which they are a part.)
    (1) Any impurity.
    (2) Any byproduct which is not used for commercial purposes.
    (3) Any chemical substance which results from a chemical reaction 
that occurs incidental to exposure of another chemical substance, 
mixture, or article

[[Page 102]]

to environmental factors such as air, moisture, microbial organisms, or 
sunlight.
    (4) Any chemical substance which results from a chemical reaction 
that occurs incidental to storage or disposal of another chemical 
substance, mixture, or article.
    (5) Any chemical substance which results from a chemical reaction 
that occurs upon end use of another chemical substance, mixture, or 
article such as an adhesive, paint, miscellaneous cleanser or other 
housekeeping product, fuel additive, water softening and treatment 
agent, photographic film, battery, match, or safety flare, and which is 
not itself manufactured or imported for distribution in commerce or for 
use as an intermediate.
    (6) Any chemical substance which results from a chemical reaction 
that occurs upon use of curable plastic or rubber molding compounds, 
inks, drying oils, metal finishing compounds, adhesives, or paints, or 
any other chemical substance formed during the manufacture of an article 
destined for the marketplace without further chemical change of the 
chemical substance except for those chemical changes that occur as 
described elsewhere in this paragraph.
    (7) Any chemical substance which results from a chemical reaction 
that occurs when (i) a stabilizer, colorant, odorant, antioxidant, 
filler, solvent, carrier, surfactant, plasticizer, corrosion inhibitor, 
antifoamer or defoamer, dispersant, precipitation inhibitor, binder, 
emulsifier, deemulsifier, dewatering agent, agglomerating agent, 
adhesion promoter, flow modifier, pH neutralizer, sequesterant, 
coagulant, flocculant, fire retardant, lubricant, chelating agent, or 
quality control reagent functions as intented, or (ii) a chemical 
substance, which is intended solely to impart a specific physiochemical 
characteristic, functions as intended.
    (8) Any nonisolated intermediate.
    (i) Any chemical substance which is manufactured solely for non-
commercial research and development purposes. Non-commercial research 
and development purposes include scientific experimentation, research, 
or analysis conducted by academic, government, or independent not-for-
profit research organizations (e.g., universities, colleges, teaching 
hospitals, and research institutes), unless the activity is for eventual 
commercial purposes.

[48 FR 21742, May 13, 1983, as amended at 51 FR 15101, Apr. 22, 1986]



Sec. 720.36  Exemption for research and development.

    (a) This part does not apply to a chemical substance if the 
following conditions are met:
    (1) The chemical substance is manufactured or imported only in small 
quantities solely for research and development.
    (2) The manufacturer or importer notifies all persons in its employ 
or to whom it directly distributes the chemical substance, who are 
engaged in experimentation, research, or analysis on the chemical 
substance, including the manufacture, processing, use, transport, 
storage, and disposal of the substance associated with research and 
development activities, of any risk to health, identified under 
paragraph (b) of this section, which may be associated with the 
substance. The notification must be made in accordance with paragraph 
(c) of this section.
    (3) The chemical substance is used by, or directly under the 
supervision of, a technically qualified individual.
    (b)(1) To determine whether notification under paragraph (a)(2) of 
this section is required, the manufacturer or importer must review and 
evaluate the following information to determine whether there is reason 
to believe there is any potential risk to health which may be associated 
with the chemical substance:
    (i) Information in its possession or control concerning any 
significant adverse reaction by persons exposed to the chemical 
substance which may reasonably be associated with such exposure.
    (ii) Information provided to the manufacturer or importer by a 
supplier or any other person concerning a health risk believed to be 
associated with the substance.
    (iii) Health and environmental effects data in its possession or 
control concerning the substance.

[[Page 103]]

    (iv) Information on health effects which accompanies any EPA rule or 
order issued under sections 4, 5, or 6 of the Act that applies to the 
substance and of which the manufacturer or importer has knowledge.
    (2) When the research and development activity is conducted solely 
in a laboratory and exposure to the chemical substance is controlled 
through the implementation of prudent laboratory practices for handling 
chemical substances of unknown toxicity, and any distribution, except 
for purposes of disposal, is to other such laboratories for further 
research and development activity, the information specified in 
paragraph (b)(1) of this section need not be reviewed and evaluated. 
(For purposes of this paragraph, a laboratory is a contained research 
facility where relatively small quantities of chemical substances are 
used on a non-production basis, and where activities involve the use of 
containers for reactions, transfers, and other handling of substances 
designed to be easily manipulated by a single individual.)
    (c)(1) The manufacturer or importer must notify the persons 
identified in paragraph (a)(2) of this section by means of a container 
labeling system, conspicuous placement of notices in areas where 
exposure may occur, written notification to each person potentially 
exposed, or any other method of notification which adequately informs 
persons of health risks which the manufacturer or importer has reason to 
believe may be associated with the substance, as determined under 
paragraph (b)(1) of this section.
    (2) If the manufacturer or importer distributes a chemical substance 
manufactured or imported under this section to persons not in its 
employ, the manufacturer or importer must in written form:
    (i) Notify those persons that the substance is to be used only for 
research and development purposes.
    (ii) Provide the notice of health risks specified in paragraph 
(c)(1) of this section.
    (3) The adequacy of any notification under this section is the 
responsibility of the manufacturer or importer.
    (d) A chemical substance is not exempt from reporting under this 
part if any amount of the substance, including as part of a mixture, is 
processed, distributed in commerce, or used, for any commercial purpose 
other than research and development, except where the chemical substance 
is processed, distributed in commerce, or used only as an impurity or as 
part of an article.
    (e) Quantities of the chemical substance, or of mixtures or articles 
containing the chemical substance, remaining after completion of 
research and development activities may be:
    (1) Disposed of as a waste in accordance with applicable Federal, 
state, and local regulations, or
    (2) Used for the following commercial purposes:
    (i) Burning it as a fuel.
    (ii) Reacting or otherwise processing it to form other chemical 
substances for commercial purposes, including extracting component 
chemical substances.
    (f) Quantities of research and development substances existing 
solely as impurities in a product or incorporated into an article, in 
accordance with paragraph (d) of this section, and quantities of 
research and development substances used solely for commercial purposes 
listed in paragraph (e) of this section, are not subject to the 
requirements of paragraphs (a), (b), and (c) of this section, once 
research and development activities have been completed.
    (g) A person who manufactures or imports a chemical substance in 
small quantities solely for research and development is not required to 
comply with the requirements of this section if the person's exclusive 
intention is to perform research and development activities solely for 
the purpose of determining whether the substance can be used as a 
pesticide.

[51 FR 15102, Apr. 22, 1986]



Sec. 720.38  Exemptions for test marketing.

    (a) Any person may apply for an exemption to manufacture or import a 
new chemical substance for test marketing. EPA may grant the exemption 
if the person demonstrates that the chemical substance will not present 
an unreasonable risk to injury to health or the environment as a result 
of the test marketing.

[[Page 104]]

    (b) Persons applying for a test-marketing exemption should provide 
the following information:
    (1) All existing data regarding health and environmental effects of 
the chemical substance, including physical/chemical properties or, in 
the absence of such data, a discussion of toxicity based on structure-
activity relationships (SAR) and relevant data on chemical analogues.
    (2) The maximum quantity of the chemical substance which the 
applicant will manufacture or import for test marketing.
    (3) The maximum number of persons who may be provided the chemical 
substance during test marketing.
    (4) The maximum number of persons who may be exposed to the chemical 
substance as a result of test marketing, including information regarding 
duration and route of such exposures.
    (5) A description of the test-marketing activity, including its 
length and how it can be distinguished from full-scale commercial 
production and research and development.
    (c) In accordance with section 5(h)(6) of the Act, after EPA 
receives an application for exemption under this section, the Agency 
will file with the Office of the Federal Register a notice containing a 
summary of the information provided in the application, to the extent it 
has not been claimed confidential.
    (d) No later than 45 days after EPA receives an application, the 
Agency will either approve or deny the application. Thereafter, EPA will 
publish a notice in the Federal Register explaining the reasons for 
approval or denial.
    (e) In approving an application for exemption, EPA may impose any 
restrictions necessary to ensure that the substance will not present an 
unreasonable risk of injury to health and the environment as a result of 
test marketing.

[48 FR 21742, May 13, 1983, as amended at 58 FR 34204, June 23, 1993]



                         Subpart C--Notice Form



Sec. 720.40  General.

    (a) Use of the notice form; electronic submissions. (1) Each person 
who is required by subpart B of this part to submit a notice must 
complete, sign, and submit a notice containing the information in the 
form and manner specified in this paragraph. The information submitted 
and all attachments (unless the attachment appears in the open 
scientific literature) must be in English. All information submitted 
must be true and correct.
    (2) Information may be submitted on paper, or electronically, as 
follows:
    (i) Information submitted on paper must be submitted in the form and 
manner set forth in EPA Form No. 7710-25, which is available from the 
Environmental Assistance Division (7408), Office of Pollution Prevention 
and Toxics, Environmental Protection Agency, 401 M St., SW., Washington, 
DC 20460. Information which is not submitted on the EPA Form No. 7710-25 
or a photocopy thereof (e.g., on a form created by commercial form-
making software) must be in a format pre-approved by the Agency.
    (ii) Information may be submitted electronically (on magnetic or 
other media) pursuant to an EPA published format for electronic 
submissions. Such submissions must comply with this format and all other 
media specifications published by EPA. Persons submitting electronically 
must still complete and submit on paper the Certification and Submitter 
Identification sections of Form 7710-25.
    (b) When to submit a notice. Each person who is required to submit a 
notice must submit the notice at least 90 calendar days before 
manufacture or import of the new chemical substance for commercial 
purposes begins.
    (c) Where to submit a notice. Each person who submits a notice must 
submit it to the address listed on the notice form.
    (d) General notice requirements. (1) Each person who submits a 
notice must provide the information described in Sec. 720.45 and 
specified on the notice form, to the extent such information is

[[Page 105]]

known to or reasonably ascertainable by the person. In accordance with 
Sec. 720.50, the notice must also include any test data in the person's 
possession or control, and descriptions of other data which are known to 
or reasonably ascertainable by the person and which concern the health 
and environmental effects of the new chemical substance.
    (2) A person who submits a notice to EPA under this part must 
provide EPA with an original and two complete copies of the notice, 
including all test data and any other information attached to the notice 
form. If information is claimed as confidential pursuant to Sec. 720.80, 
a sanitized copy must also be provided.
    (e) Agency or joint submissions. (1) A manufacturer or importer may 
designate an agent to submit the notice. Both the manufacturer or 
importer and the agent must sign the certification on the form.
    (2) A manufacturer or importer may authorize another person, (e.g., 
a foreign manufacturer or supplier, or a toll manufacturer) to report 
some of the information required in the notice to EPA on its behalf. If 
separate portions of a joint notice are not submitted together, the 
submitter should indicate which information will be supplied by another 
person and identify that person. The other person must submit the 
information on the appropriate part of the notice form. The manufacturer 
or importer and any other person supplying the information must sign the 
certification provided on their respective notice forms.
    (3) If EPA receives a submission which does not include information 
required by this rule, which the submitter indicates that it has 
authorized another person to provide, the notice review period will not 
begin until EPA receives that information.
    (f) New information. During the notice review period, if the 
submitter possesses, controls, or knows of new information that 
materially adds to, changes, or otherwise makes significantly more 
complete the information included in the notice, the submitter must that 
information to the address listed on the notice form within ten days of 
receiving the new information, but no later than five days before the 
end of the notice review period. The new submission must clearly 
identify the submitter and the notice to which the new information is 
related. If the new information becomes available during the last five 
days of the notice review period, the submitter must immediately inform 
its EPA contract for that notice by telephone.
    (g) Chemical substances subject to a section 4 test rule. (1) Except 
as provided in paragraph (g)(3) of this section, if (i) A person intends 
to manufacture or import a new chemical substance which is subject to 
the notification requirements of this part, and (ii) The chemical 
substance is subject to a test rule promulgated under section 4 of the 
Act before the notice is submitted, section 5(b)(1) of the Act requires 
the person to submit the test data required by the testing rule with the 
notice. The person must submit the data in the form and manner specified 
in the test rule and in accordance with Sec. 720.50. If the person does 
not submit the test data, the submission is incomplete and EPA will 
follow the procedures in Sec. 720.65.
    (2) If EPA has granted the submitter an exemption under section 4(c) 
of the Act from the requirement to conduct tests and submit data, the 
submitter may not submit a notice until EPA receives the test data.
    (3) If EPA has granted the submitter an exemption under section 4(c) 
of the Act and if another person previously has submitted the test data 
to EPA, the exempted person may either submit the test data or provide 
the following information as part of the notice:
    (i) The name, title, and address of the person who submitted the 
test data to EPA.
    (ii) The date the test data were submitted to EPA.
    (iii) A citation for the test rule.
    (iv) A description of the exemption and a reference identifying it.
    (h) Chemical substances subject to a section 5(b)(4) rule. (1) If a 
person (i) intends to manufacture or import a new chemical substance 
which is subject to the notification requirements of this part and which 
is subject to a rule issued under section 5(b)(4) of the Act; and (ii) 
is not required by a rule issued under section 4 of the Act to submit

[[Page 106]]

test data for the substance before the submission of a notice, the 
person must submit to EPA data described in paragraph (h)(2) of this 
section at the time the notice is submitted.
    (2) Data submitted under paragraph (h)(1) of this section must be 
data which the person submitting the notice believes show that the 
manufacture, processing, distribution in commerce, use and disposal of 
the substance, or any combination of such activities, will not present 
an unreasonable risk of injury to health or the environment.

[48 FR 21742, May 13, 1983, as amended at 58 FR 34204, June 23, 1993; 60 
FR 16309, Mar. 29, 1995]



Sec. 720.45  Information that must be included in the notice form.

    Each person who submits a notice must include the information 
specified in the notice form to the extent it is known to or reasonably 
ascertainable by the submitter. However, no person is required to 
include information which relates solely to exposure of human or 
ecological populations outside of the United States. The notice form 
requires the following information relating to the manufacture, 
processing, distribution in commerce, use, and disposal of the new 
chemical substance:
    (a)(1) The specific chemical identity of the substance that the 
person intends to manufacture or import, which includes the following:
    (i) The currently correct Chemical Abstracts (CA) name for the 
substance, based on the Ninth Collective Index (9CI) of CA nomenclature 
rules and conventions, and consistent with listings for similar 
substances in the Inventory. For each substance having a chemical 
composition that can be represented by a specific, complete chemical 
structure diagram (a Class 1 substance), a CA Index Name must be 
provided. For each chemical substance that cannot be fully represented 
by a complete, specific chemical structure diagram (a Class 2 
substance), or if the substance is a polymer, a CA Index Name or CA 
Preferred Name must be provided (whichever is appropriate based on CA 
9CI nomenclature rules and conventions). In addition, for a Class 2 
substance, the notice must identify the immediate chemical precursors 
and reactants by specific chemical name and Chemical Abstracts Service 
Registry Number (CASRN), if the number is available. Tradenames or 
generic names of chemical precursors or reactants are not acceptable as 
substitutes for specific chemical names.
    (ii) The currently correct CASRN for the substance if a CASRN 
already exists for the substance.
    (iii) For a Class 1 substance and for any Class 2 substance for 
which a definite molecular formula is known or reasonably ascertainable, 
the correct molecular formula.
    (iv) For a Class 1 substance, a complete, correct chemical structure 
diagram; for a Class 2 substance or polymer, a correct representative or 
partial chemical structure diagram, as complete as can be known, if one 
can be reasonably ascertained.
    (2) For a polymer, the submitter must also report the following:
    (i) The specific chemical name and CASRN, if the number is 
available, of each monomer and other reactant used, at any weight 
percent, to manufacture the polymer. Tradenames or generic names of 
chemical reactants or monomers are not acceptable as substitutes for 
specific chemical names.
    (ii) The typical percent by weight of each monomer and other 
reactant in the polymer (weight of the monomer or other reactant 
expressed as a percentage of the weight of the polymeric chemical 
substance manufactured), and the maximum residual amount of each monomer 
present in the polymer.
    (iii) For monomers and other reactants used at 2 weight percent or 
less (based on the dry weight of the polymer manufactured), indicate on 
the PMN form any such monomers and other reactants that should be 
included as part of the polymer description on the Inventory, where the 
weight percent is based on either (A) the weight of monomer or other 
reactant actually charged to the reaction vessel, or (B) the minimum 
weight of monomer or other reactant required in theory to account for 
the actual weight of monomer or other reactant molecules or fragments 
chemically incorporated (chemically combined) in the polymeric substance 
manufactured.

[[Page 107]]

    (iv) For a determination that 2 weight percent or less of a monomer 
or other reactant is incorporated (chemically combined) in a polymeric 
substance manufactured, as specified in paragraphs (a)(2)(iii)(B) of 
this section, analytical data or appropriate theoretical calculations 
(if it can be documented that analytical measurement is not feasible or 
not necessary) to support this determination must be maintained at the 
site of manufacture or import of the polymer.
    (v) Measured or estimated values of the minimum number-average 
molecular weight of the polymer and the amount of low molecular weight 
species below 500 and below 1,000 molecular weight, with a description 
of how the measured or estimated values were obtained.
    (3) The person must use one of the following two methods to develop 
or obtain the specified chemical identity information reported under 
paragraphs (a) (1) and (2) of this section and must identify the method 
used in the notice:
    (i) Method 1. Obtain the correct chemical identity information 
required by paragraphs (a) (1) and (2) of this section directly from the 
Chemical Abstracts Service (CAS), specifically from the CAS Registry 
Services Inventory Expert Service, prior to submitting a notice to EPA. 
A copy of the chemical identification report obtained from CAS must be 
submitted with the notice.
    (ii) Method 2. Obtain the correct chemical identity information 
required by paragraphs (a) (1) and (2) from any source. The notice will 
be incomplete according to Sec. 720.65(c)(1)(vi) if the person uses 
Method 2 and any chemical identity information is determined to be 
incorrect by EPA.
    (4) If an importer submitting the notice cannot provide all the 
information specified in paragraphs (a) (1) and (2) of this section 
because it is claimed as confidential by the foreign supplier of the 
substance, the importer must have the foreign supplier follow the 
procedures in paragraph (a)(3) of this section and provide the correct 
chemical identity information specified in paragraphs (a) (1) and (2) of 
this section directly to EPA in a joint submission or as a letter of 
support to the notice, which clearly references the importer's notice 
and PMN User Fee Identification Number. The statutory review process 
will commence upon receipt of both the notice and the complete, correct 
information.
    (5) If a manufacturer cannot provide all the information specified 
in paragraphs (a) (1) and (2) of this section because the new chemical 
substance is manufactured using a reactant having a specific chemical 
identity claimed as confidential by its supplier, the manufacturer must 
submit a notice directly to EPA containing all the information known by 
the manufacturer about the chemical identity of the reported substance 
and its proprietary reactant. In addition, the manufacturer must ensure 
that the supplier of the confidential reactant submit a letter of 
support directly to EPA providing the specific chemical identity of the 
confidential reactant, including the CAS number, if available, and the 
appropriate PMN or exemption number, if applicable. The letter of 
support must reference the manufacturer's name and PMN User Fee 
Identification Number under Sec. 700.45(c)(3) of this chapter. The 
statutory review period will commence upon receipt of both the notice 
and the letter of support.
    (b) The impurities anticipated to be present in the substance by 
name, CAS Registry number, and weight percent of the total substance.
    (c) Known synonyms or trade names of the new chemical substance.
    (d) A description of the byproducts resulting from the manufacture, 
processing, use, and disposal of the new chemical substance.
    (e) The estimated maximum amount to be manufactured or imported 
during the first year of production and the estimated maximum amount to 
be manufactured or imported during any 12-month period during the first 
three years of production.
    (f) A description of intended categories of use by function and 
application, the estimated percent of production volume devoted to each 
category of use, and the percent of the new substance in the formulation 
for each commercial or consumer use.
    (g) For sites controlled by the submitter:

[[Page 108]]

    (1) The identity of sites where the new substance will be 
manufactured, processed, or used.
    (2) A process description of each manufacture, processing, and use 
operation which includes a diagram of the major unit operations and 
chemical conversions, the identity and entry point of all feedstocks, 
and the points of release of the new chemical substance.
    (3) Worker exposure information, including worker activities, 
physical form of the new substance to which workers may be exposed, the 
number of workers, and the duration of activities.
    (4) Information on release of the new substance to the environment, 
including the quantity and media of release and type of control 
technology used.
    (h) For sites not controlled by the submitter, a description of each 
type of processing and use operation involving the new chemical 
substance, including identification of the estimated number of 
processing or use sites, situations in which worker exposure to and/or 
environmental release of the new chemical substance will occur, the 
number of workers exposed and the duration of exposure, and controls 
which limit worker exposure and environmental release.

[48 FR 21742, May 13, 1983, as ameneded at 60 FR 16310, Mar. 29, 1995]



Sec. 720.50  Submission of test data and other data concerning the health and environmental effects of a substance.

    (a) Test data on the new chemical substance in the possession or 
control of the submitter. (1) Except as provided in paragraph (d) of 
this section, each notice must contain all test data in the submitter's 
possession or control which are related to the effects on health or the 
environment of any manufacture, processing, distribution in commerce, 
use, or disposal of the new chemical substance or any mixture or article 
containing the new chemical substance, or any combination of such 
activities. This includes test data concerning the new chemical 
substance in a pure, technical grade, or formulated form.
    (2) A full report or standard literature citation must be submitted 
for the following types of test data:
    (i) Health effects data.
    (ii) Ecological effects data.
    (iii) Physical and chemical properties data.
    (iv) Environmental fate characteristics.
    (v) Monitoring data and other test data related to human exposure to 
or environmental release of the chemical substance.
    (3)(i) If the data do not appear in the open scientific literature, 
the submitter must provide a full report. A full report includes the 
experimental methods and materials, results, discussion and data 
analysis, conclusions, references, and the name and address of the 
laboratory that developed the data.
    (ii) If the data appear in the open scientific literature, the 
submitter need only provide a standard literature citation. A standard 
literature citation includes author, title, periodical name, date of 
publication, volume, and page numbers.
    (4)(i) If a study, report, or test is incomplete when a person 
submits a notice, the submitter must identify the nature and purpose of 
the study; name and address of the laboratory developing the data; 
progress to date; types of data collected; significant preliminary 
results; and anticipated completion date.
    (ii) If a test or experiment is completed before the notice review 
period ends, the person must submit the study, report, or test to the 
address listed on the notice form, as specified in paragraph (a)(3)(i) 
of this section, within ten days of receiving it, but no later than five 
days before the end of the review period. If the test or experiment is 
completed during the last five days of the review period, the submitter 
must immediately inform its EPA contact for that notice by telephone.
    (5) For test data in the submitter's possession or control which are 
not listed in paragraph (a)(2) of this section, a person is not required 
to submit a complete report. The person must submit a summary of the 
data. If EPA so requests, the person must submit a full report within 
ten days of the request, but no later than five days before the end of 
the review period.

[[Page 109]]

    (6) All test data described by paragraph (a) are subject to these 
requirements, regardless of their age, quality, or results.
    (b) Other data concerning the health and environmental effects of 
the new chemical substance that are known to or reasonably ascertainable 
by the submitter. (1) Except as provided in paragraph (d) of this 
section, any person who submits a notice must describe the following 
data, including any data from a health and safety study, if the data are 
related to the effects on health or the environment of any manufacture, 
processing, distribution in commerce, use, or disposal of the new 
chemical substance, of any mixture or article containing the new 
chemical substance, or of any combination of such activities:
    (i) Any data, other than test data, in the submitter's possession or 
control.
    (ii) Any data, including test data, which are not in the submitter's 
possession or control, but which are known to or reasonably 
ascertainable by the submitter. For the purposes of this section, data 
are known to or reasonably ascertainable by the submitter if the data 
are known to any of its employees or other agents who are associated 
with the research and development, test marketing, or commercial 
marketing of the substance.
    (2) Data that must be described include data concerning the new 
chemical substance in a pure, technical grade, or formulated form.
    (3) The description of data reported under this paragraph must 
include:
    (i) If the data appear in the open scientific literature, a standard 
literature citation, which includes the author, title, periodical name, 
date of publication, volume, and pages.
    (ii) If the data are not contained in the open scientific 
literature, a description of the type of data and summary of the 
results, if available, and the names and addresses of persons the 
submitter believes may have possession or control of the data.
    (4) All data described by this paragraph are subject to these 
requirements, regardless of their age, quality, or results; and 
regardless of whether they are complete at the time the notice is 
submitted.
    (c) [Reserved]
    (d) Data that need not be submitted--(1) Data previously submitted 
to EPA. (i) A person need not submit any data previously submitted to 
EPA with no claims of confidentiality if the notice includes the office 
or person to whom the data were submitted, the date of submission, and, 
if appropriate, a standard literature citation as specified in paragraph 
(a)(3)(ii) of this section.
    (ii) For data previously submitted to EPA with a claim of 
confidentiality, the person must resubmit the data with the notice and 
any claim of confidentiality, under Sec. 720.80.
    (2) Efficacy data. This part does not require submission of any data 
related solely to product efficacy. This does not exempt a person from 
submitting any of the data specified in paragraph (a), (b), or (c) of 
this section.
    (3) Non-U.S. exposure data. This part does not require submission of 
any data which relates only to exposure of humans or the environment 
outside the United States. This does not exclude nonexposure data such 
as data on health effects (including epidemiological studies), 
ecological effects, physical and chemical properties, or environmental 
fate characteristics.

[48 FR 21742, May 13, 1983, as amended at 51 FR 15102, Apr. 22, 1986]



Sec. 720.57  Imports.

    (a) Except as otherwise provided in this section, the provisions of 
this subpart C apply to each person who submits a notice for a new 
chemcial substance which he or she intends to import for a commercial 
purpose. In addition, each importer must comply with this section.
    (b) EPA will hold the principal importer, or the importer that EPA 
determines must submit the notice when there is no principal importer 
under Sec. 720.22(b)(2), liable for complying with this part, for 
completing the notice form and for the completeness and truthfulness of 
all information which it submits.

[[Page 110]]



                    Subpart D--Disposition of Notices



Sec. 720.60  General.

    This subpart establishes procedures that EPA will follow in 
reviewing notices.



Sec. 720.62  Notice that notification is not required.

    When EPA receives a notice, EPA will review it to determine whether 
the chemical substance is subject to the requirements of this part. If 
EPA determines that the chemical substance is not subject to these 
requirements, EPA will notify the submitter that section 5 of the Act 
does not prevent the manufacture or import of the substance and that the 
submission is not a notice under this part.

[48 FR 21742, May 13, 1983, as amended at 58 FR 34204, June 23, 1993]



Sec. 720.65  Acknowledgment of receipt of a notice; errors in the notice; incomplete submissions; false and misleading statements.

    (a) Notification to submitter. EPA will acknowledge receipt of each 
notice by sending the submitter a letter that identifies the 
premanufacture notice number assigned to the new chemical substance and 
the date on which the review period begins. The review period will begin 
on the date the notice is received by the Office of Pollution Prevention 
and Toxics Document Control Officer. The acknowledgment does not 
constitute a finding by EPA that the notice, as submitted, is in 
compliance with this part.
    (b) Errors in the notice. (1) Within 30 days of receipt of the 
notice, EPA may request that the submitter remedy errors in the notice. 
The following are examples of such errors:
    (i) Failure to date the notice form.
    (ii) Typographical errors that cause data to be misleading or 
answers to any questions to be unclear.
    (iii) Contradictory information.
    (iv) Ambiguous statements or information.
    (2) In the request to correct the notice, EPA will explain the 
action which the submitter must take to correct the notice.
    (3) If the submitter fails to correct the notice within 15 days of 
receipt of the request, EPA may extend the notice period under section 
(5)(c) of the Act, in accordance with Sec. 720.75(c).
    (c) Incomplete submissions. (1) A submission is not complete, and 
the notification period does not begin, if:
    (i) The wrong person submits the notice form.
    (ii) The submitter does not sign the notice form.
    (iii) Some or all of the information in the notice or the 
attachments are not in English, except for published scientific 
literature.
    (iv) The submitter does not use the notice form.
    (v) The submitter does not provide information that is required by 
section 5(d)(1) (B) and (C) of the Act and Sec. 720.50.
    (vi) The submitter does not provide information required on the 
notice form and by Sec. 720.45 or indicate that it is not known to or 
reasonably ascertainable by the submitter.
    (vii) The submitter does not submit a second copy of the submission 
with all confidential information deleted for the public file, as 
required by Sec. 720.80(b)(2).
    (viii) The submitter does not include any information required by 
section 5(b)(1) of the Act and pursuant to a rule promulgated under 
section 4 of the Act, as required by Sec. 720.40(g).
    (ix) The submitter does not submit data which the submitter believes 
show that the chemical substance will not present an unreasonable risk 
of injury to health or the environment, if EPA has listed the chemical 
substance under section 5(b)(4) of the Act, as required in 
Sec. 720.40(h).
    (2)(i) If EPA receives an incomplete submission, the Director, or 
his or her delegate, will notify the submitter within 30 days of receipt 
that the submission is incomplete and that the notice review period will 
not begin until EPA receives a complete notice.
    (ii) If EPA obtains additional information during the notice review 
period that indicates the original submission was incomplete, the 
Director, or his or her delegate, may declare the submission incomplete 
within 30 days after EPA obtains the additional information and so 
notify the submitter.

[[Page 111]]

    (3) The notification that a submission is incomplete under paragraph 
(c)(2) (i) or (ii) of this section will include:
    (i) A statement of the basis of EPA's determination that the 
submission is incomplete.
    (ii) The requirements for correcting the incomplete submission.
    (iii) Information on procedures under paragraph (c)(4) of this 
section for filing objections to the determination or requesting 
modification of the requirements for completing the submission.
    (4) Within ten days after receipt of notification by EPA that a 
submission is incomplete, the submitter may file written objections 
requesting that EPA accept the submission as a complete notice or modify 
the requirements necessary to complete the submission.
    (5)(i) EPA will consider the objections filed by the submitter. The 
Director, or his or her delegate, will determine whether the submission 
was complete or incomplete, or whether to modify the requirements for 
completing the submission. EPA will notify the submitter in writing of 
EPA's response within ten days of receiving the objections.
    (ii) If the Director, or his or her delegate, determines, in 
response to the objection, that the submission was complete, the notice 
review period will be deemed suspended on the date EPA declared the 
notice incomplete, and will resume on the date that the notice is 
declared complete. The submitter need not correct the notice as EPA 
originally requested. If EPA can complete its review within 90 days from 
the date of the original submission, the Director, or his or her 
delegate, may inform the submitter that the running of the review period 
will resume on the date EPA originally declared it incomplete.
    (iii) If the Director, or his or her delegate, modifies the 
requirements for completing the submission or concurs with EPA's 
original determination, the notice review period will begin when EPA 
receives a complete notice.
    (d) Materially false or misleading statements. If EPA discovers at 
any time that person submitted materially false or misleading statements 
in the notice, EPA may find that the notice was incomplete from the date 
it was submitted, and take any other appropriate action.



Sec. 720.70  Notice in the Federal Register.

    (a) Filing of Federal Register notice. In accordance with section 
5(d)(2) of the Act, after EPA receives a notice, EPA will file with the 
Office of the Federal Register a notice including the information 
specified in paragraph (b) of this section.
    (b) Contents of notice. (1) In the public interest, the specific 
chemical identity listed in the notice will be published in the Federal 
Register unless the submitter has claimed chemical identity 
confidential. If the submitter claims confidentiality, a generic name 
will be published in accordance with Sec. 720.85(a)(3).
    (2) The categories of use of the new chemical substance will be 
published as reported in the notice unless this information is claimed 
confidential. If confidentiality is claimed, the generic information 
which is submitted under Sec. 720.87(b) will be published.
    (3) A list of data submitted in accordance with Sec. 720.50(a) will 
be published. In addition, for test data submitted in accordance with 
Sec. 720.40(g), a summary of the data will be published.
    (4) The submitter's identity will be published, unless the submitter 
has claimed it confidential.



Sec. 720.75  Notice review period.

    (a) Length of notice review period. The notice review period 
specified in section 5(a) of the Act runs for 90 days from the date the 
Document Control Officer for the Office of Pollution Prevention and 
Toxics receives a complete notice, or the date EPA determines the notice 
is complete under Sec. 720.65(c), unless the Agency extends the period 
under section 5(c) of TSCA and paragraph (c) of this section.
    (b) Suspension of the running of the notice review period. (1) A 
submitter may voluntarily suspend the running of the notice review 
period if the Director or his or her delegate agrees. If the Director 
does not agree, the review period will continue to run, and EPA will 
notify the submitter. A submitter may

[[Page 112]]

request a suspension at any time during the notice review period. The 
suspension must be for a specified period of time.
    (2) A request for suspension may be made in writing to the Document 
Control Office (7407), Office of Pollution Prevention and Toxics, U.S. 
Environmental Protection Agency, Room G-099, 401 M St., SW., Washington, 
DC., 20460. The suspension also may be made orally, including by 
telephone, to the submitter's EPA contact for that notice. EPA will send 
the submitter a written confirmation that the suspension has been 
granted.
    (i) An oral request may be granted for 15 days only. To obtain a 
longer suspension, the Document Control Officer for the Office of 
Pollution Prevention and Toxics must receive written confirmation of the 
oral request. The notice review period is suspended as of the date of 
the oral request.
    (ii) If the submitter has not made a previous oral request, the 
running of the notice review period is suspended as of the date of 
receipt of the written request by the Document Control Officer for the 
Office of Pollution Prevention and Toxics.
    (c) Extension of notice review period. (1) At any time during the 
notice review period, EPA may determine that good cause exists to extend 
the notice review period specified in paragraph (a) of this section.
    (2) If EPA makes such a determination, EPA will:
    (i) Notify the submitter that EPA is extending the notice review 
period for a specified length of time, and state the reasons for the 
extension.
    (ii) Issue a notice for publication in the Federal Register which 
states that EPA is extending the notice review period and gives the 
reasons for the extension.
    (3) The initial extension may be for a period of up to 90 days. If 
the initial extension is for less than 90 days, EPA may make additional 
extensions. However, the total period of extensions may not exceed 90 
days for any notice.
    (4) The following are examples of situations in which EPA may find 
that good cause exists for extending the notice review period:
    (i) EPA has reviewed the notice and determined that there is a 
significant possibility that the chemical substance will be regulated 
under section 5(e) or section 5(f) of the Act, but EPA is unable to 
initiate regulatory action within the initial 90-day period.
    (ii) EPA has reviewed the submission and is seeking additional 
information.
    (iii) EPA has received significant additional information during the 
notice review period.
    (iv) The submitter has failed to correct a notice after receiving 
EPA's request under Sec. 720.65(b).
    (d) Notice of expiration of notice review period. EPA will notify 
the submitter that the notice review period has expired or that EPA has 
completed its review of the notice. Expiration of the review period does 
not constitute EPA approval or certification of the new chemical 
substance, and does not mean that EPA may not take regulatory action 
against the substance in the future. After expiration of the statutory 
notice review period, in the absence of regulatory action by EPA under 
section 5(e), 5(f), or 6(a) of the Act, the submitter may manufacture or 
import the chemical substance even if the submitter has not received 
notice of expiration.
    (e) Withdrawal of a notice by the submitter. (1) A submitter may 
withdraw a notice during the notice review period. A statement of 
withdrawal must be made in writing to the Document Control Office 
(7407), Office of Pollution Prevention and Toxics, U.S. Environmental 
Protection Agency, Room G-099, 401 M St., SW., Washington, DC., 20460. 
The withdrawal is effective upon receipt of the statement by the 
Document Control Officer.
    (2) If a manufacturer or importer which withdrew a notice later 
resubmits a notice for the same chemical substance, a new notice review 
period begins.

[48 FR 21742, May 13, 1983, as amended at 53 FR 12523, Apr. 15, 1988; 58 
FR 34204, June 23, 1993; 60 FR 34464, July 3, 1995]



Sec. 720.78  Recordkeeping.

    (a) Any person who submits a notice under this part must retain 
documentation of information in the notice, including (1) other data, as 
defined in

[[Page 113]]

Sec. 720.50(b), in the submitter's possession or control; and (2) 
records of production volume for the first three years of production or 
import, the date of commencement of manufacture or import, and 
documentation of this information. This information must be retained for 
five years from the date of commencement of manufacture of import.
    (b)(1) Persons who manufacture or import a chemical substance under 
Sec. 720.36 must retain the following records:
    (i) Copies of, or citations to, information reviewed and evaluated 
under Sec. 720.36(b)(1) to determine the need to make any notification 
of risk.
    (ii) Documentation of the nature and method of notification under 
Sec. 720.36(c)(1) including copies of any labels or written notices 
used.
    (iii) Documentation of prudent laboratory practices used instead of 
notification and evaluation under Sec. 720.36(b)(2).
    (iv) The names and addresses of any persons other than the 
manfacturer or importer to whom the substance is distributed, the 
identity of the substance to the extent known, the amount distributed, 
and copies of the notifications required under Sec. 720.36(c)(2). These 
records are not required when substances are distributed as impurities 
or incorporated into an article, in accordance with paragraph (d) of 
this section.
    (2) A person who manufactures or imports a chemical substance under 
Sec. 720.36 and who manufactures or imports the substance in quantities 
greater than 100 kilograms per year must retain records of the identity 
of the substance to the extent known, the production volume of the 
substance, and the person's disposition of the substance. The person is 
not required to maintain records of the disposition of products 
containing the substance as an impurity or of articles incorporating the 
substances.
    (3) Records under this paragraph must be retained for 5 years after 
they are developed.
    (c) Any person who obtains a test-marketing exemption under this 
part must retain documentation of information in the application and 
documentation of compliance with any restrictions imposed by EPA when it 
granted the application. This information must be retained for five 
years from the final date of manufacture or import under the exemption.

[48 FR 21742, May 13, 1983; 48 FR 33872, July 26, 1983, as amended at 51 
FR 15102, Apr. 22, 1986; 58 FR 34204, June 23, 1993]



       Subpart E--Confidentiality and Public Access to Information



Sec. 720.80  General provisions.

    (a) A person may assert a claim of confidentiality for any 
information which he or she submits to EPA under this part.
    (b) Any claim of confidentiality must accompany the information when 
it is submitted to EPA.
    (1)(i) For information submitted on the notice form, the claim(s) 
must be asserted on the form in the manner prescribed on the notice 
form.
    (ii) When a person submits information in an attachment, the 
claim(s) must be asserted in the attachment as described on the notice 
form.
    (2) If any information is claimed as confidential, the person must 
submit, in addition to the copies specified by Sec. 720.40, a sanitized 
copy of the notice form (or electronic submission) and any attachments.
    (i) The original and two copies of the notice, specified at 
Sec. 720.40 (or electronic submission) and attachments must be complete. 
The submitter must designate that information which is claimed as 
confidential in the manner prescribed on the notice form (or in EPA's 
electronic submission instructions).
    (ii) The sanitized copy must be complete except that all information 
claimed as confidential in the original must be deleted. EPA will place 
this sanitized copy in the public file.
    (iii) If the person does not provide the sanitized copy, or 
information in a health and safety study (except information claimed as 
confidential in accordance with Sec. 720.90), the submission will be 
deemed incomplete and the notice review period will not begin until EPA 
receives the sanitized copy or the health and safety study information 
is included, in accordance with Sec. 720.65(c)(1)(vii).

[[Page 114]]

    (c) EPA will disclose information that is subject to a claim of 
confidentiality asserted under this section only to the extent permitted 
by the Act, this subpart, and part 2 of this title.
    (d) If a notice submitter does not assert a claim of confidentiality 
for information at the time it is submitted to EPA, EPA may make the 
information public and place it in the public file without further 
notice to the submitter.

[48 FR 21742, May 13, 1983, as amended at 58 FR 34204, June 23, 1993; 60 
FR 16311, Mar. 29, 1995]



Sec. 720.85  Chemical identity.

    (a) Claims applicable to the period prior to commencement of 
manufacture or import. (1)(i) A person who submits information to EPA 
under this part may assert a claim of confidentiality for the chemical 
identity of the new chemical substance. This claim will apply only to 
the period prior to the commencement of manufacture or import for 
commercial purposes. A submitter may assert this claim only if the 
submitter believes that public disclosure prior to commencement of 
manufacture or import of the fact that anyone intends to manufacture or 
import the specific chemical substance for commercial purposes would 
reveal confidential business information.
    (ii) If the notice includes a health and safety study concerning the 
new chemical substance and if the claim for confidentiality with respect 
to the chemical identity is denied in accordance with Sec. 720.90(c), 
EPA will deny a claim asserted under this paragraph.
    (2) Any person who asserts a claim of confidentiality for chemical 
identity under this paragraph must provide one of the following items at 
the time the notice is submitted:
    (i) The generic name which was accepted by EPA in the prenotice 
consultation conducted under paragraph (a)(3) of this section.
    (ii) One generic name that is only as generic as necessary to 
protect the confidential chemical identity of the particular chemical 
substance. The name should reveal the specific chemical identity to the 
maximum extent possible. The generic name will be subject to EPA review 
and approval at the time a notice of commencement is submitted.
    (3)(i) Any person who intends to assert a claim of confidentiality 
for the chemical identity of a new chemical substance may seek a 
determination by EPA of an appropriate generic name for the substance 
before submitting a notice. For this purpose, the person should submit 
to EPA:
    (A) The chemical identity of the substance.
    (B) A proposed generic name(s) which in only as generic as necessary 
to protect the confidential chemical identity of the new chemical 
substance. The name(s) should reveal the chemical identity of the 
substance to the maximum extent possible.
    (ii) Within 30 days, EPA will inform the submitter either that one 
of the proposed generic names is adequate or that none is adequate and 
further consultation is necessary.
    (4) If a submitter claims chemical identity to be confidential under 
this paragraph, and if the submitter complies with paragraph (a)(2) of 
this section, EPA will issue for publication in the Federal Register 
notice described in Sec. 720.70 the generic name proposed by the 
submitter or one agreed upon by EPA and the submitter.
    (b) Claims applicable to the period after commencement of 
manufacture or import. (1) Any claim of confidentiality under paragraph 
(a) of this section is applicable only until the substance is 
manufactured or imported for commercial purposes and becomes eligible 
for inclusion on the Inventory. To maintain the confidential status of 
the chemical identity when the substance is added to the Inventory, a 
submitter must reassert the confidentiality claim and substantiate the 
claim in the notice of commencement of manufacture required uner 
Sec. 720.102. A submitter may not claim the chemical indentity 
confidential for the period after commencement of manufacture or import 
unless the submitter claimed the chemical identity confidential for the 
period prior to commencement of manufacture or import under paragraph 
(a) of this section.
    (2)(i) A person who believes that public disclosure of the fact that 
anyone

[[Page 115]]

manfactures or imports the new chemical substance for commercial 
purposes would reveal confidential business information may assert a 
claim of confidentiality under this paragraph.
    (ii) If the notice includes a health and safety study concerning the 
new chemical substance, and if the claim for confidentiality with 
respect to the chemical identity is denied in accordance with 
Sec. 720.90(c), EPA will deny a claim asserted under this paragraph.
    (3) Any person who asserts a confidentiality claim for chemical 
identity must:
    (i) Comply with the requirements of paragraph (a)(3) of this section 
regarding submission of a generic name.
    (ii) Agree that EPA may disclose to a person with a bona fide intent 
to manufacture or import the chemical substance the fact that the 
particular chemical substance is included on the confidential Inventory 
for purposes of notification under section 5(a)(1)(A) of the Act.
    (iii) Have available for the particular chemical substance, and 
agree to furnish to EPA upon request:
    (A) An elemental analysis.
    (B) Either an X-ray diffraction pattern (for inorganic substances), 
a mass spectrum (for most other substances), or an infrared spectrum of 
the particular chemical substance, or if such data do not resolve 
uncertainties with respect to the identity of the chemical substance, 
additional or alternative spectra or other data to identify the chemical 
substance.
    (iv) Provide a detailed written substantiation of the claim, by 
answering the following questions:
    (A) What harmful effects to your competitive position, if any, do 
you think would result if EPA publishes on the Inventory the identity of 
the chemical substance? How could a competitor use such information 
given the fact that the identity of the substance otherwise would appear 
on the Inventory of chemical substances with no link between the 
substance and your company or industry? How substantial would the 
harmful effects of disclosure be? What is the casual relationship 
between the disclosure and the harmful effects?
    (B) For what period of time should confidential treatment be given? 
Until a specific date, the occurrence of a specific event, or 
permanently? Why?
    (C) Has the chemical substance been patented? If so, have you 
granted licenses to others with respect to the patent as it applies to 
the chemical substance? If the chemical substance has been patented and 
therefore disclosed through the patent, why should it be treated as 
confidential for purposes of the Inventory?
    (D) Has the identity of the chemical substance been kept 
confidential to the extent that your competitors do not know it is being 
manufactured on imported for a commercial purpose by anyone?
    (E) Is the fact that someone is manufacturing or importing this 
chemical substance for commercial purposes available to the public, 
e.g., in technical journals or other publications; in libraries; or in 
State, local, or Federal agency public files?
    (F) What measures have you taken to prevent undesired disclosure of 
the fact that you are manufacturing or importing this substance for a 
commercial purpose?
    (G) To what extent has the fact that you are manufacturing or 
importing this chemical substance for a commercial purpose been 
disclosed to others? What precautions have you taken in regard to these 
disclosures? Has this information been disclosed to the public or to 
competitors?
    (H) In what form does this particular chemical substance leave the 
site of manufacture, e.g., as part of a product; in an effluent or 
emission stream? If so, what measures have you taken to guard against 
discovery of its identity?
    (I) If the chemical substance leaves the site of manufacture in a 
product that is available to either the public or your competitors, can 
they identify the substance by analyzing the product?
    (J) For what purpose do you manufacture or import the substance?
    (K) Has EPA, another Federal agency, or any Federal court made any 
pertinent confidentiality determinations regarding this chemical 
substance? If so, copies of such determinations must be included in the 
substantiation.
    (L) If the notice includes a health and safety study concerning the 
new chemical substance, the submitter

[[Page 116]]

must also answer the questions in Sec. 720.90(b)(2).
    (4) If the submitter does not meet the requirements of this 
paragraph, EPA will deny the claim of confidentiality.
    (5)(i) EPA will publish a generic name on the public Inventory if:
    (A) The submitter asserts a claim of confidentiality in accordance 
with this paragraph.
    (B) No claim for confidentiality of the specific chemical identity 
as part of a health and safety study has been denied in accordance with 
part 2 of this title or Sec. 720.90.
    (ii) Publication of a generic name on the public Inventory does not 
create a category for purposes of the Inventory. Any person who has a 
bona fide intent to manufacture or import a chemical substance which is 
described by a generic name on the public Inventory may submit an 
inquiry to EPA under Sec. 720.25(b) to determine whether the particular 
chemical substance is included on the confidential Inventory.
    (iii) Upon receipt of a request described in Sec. 720.25(b), EPA may 
require the submitter which originally asserted confidentiality for a 
chemical substance to submit to EPA the information listed in paragraph 
(b)(3)(iii) of this section.
    (iv) Failure to submit any of the information required under 
paragraph (b)(3)(iii) of this section within ten days of a request by 
EPA under this paragraph is a waiver of the original submitter's 
confidentiality claim. In this event, EPA may place the specific 
chemical identity on the public Inventory without further notice to the 
original submitter.
    (6) If a submitter asserts a claim of confidentiality under this 
paragraph, EPA will examine the generic chemical name proposed by the 
submitter.
    (i) If EPA determines that the generic name proposed by the 
submitter is only as generic as necessary to protect the confidential 
identity of the particular chemical substance, EPA will place that 
generic name on the public Inventory.
    (ii) If EPA determines that the generic name proposed by the 
submitter is more generic than necessary to protect the confidential 
identity, EPA will propose in writing, for review by the submitter, an 
alternative generic name that will reveal the chemical identity of the 
chemical substance to the maximum extent possible.
    (iii) If the generic name proposed by EPA is acceptable to the 
submitter, EPA will place that generic name on the public Inventory.
    (iv) If the generic name proposed by EPA is not acceptable to the 
submitter, the submitter must explain in detail why disclosure of that 
generic name would reveal confidential business information and propose 
another generic name which is only as generic as necessary to protect 
the confidential identity. If EPA does not receive a response from the 
submitter within 30 days after the submitter receives the proposed name, 
EPA will place EPA's chosen generic name on the public Inventory. If the 
submitter does provide the information requested, EPA will review the 
response. If the submitter's proposed generic name is acceptable, EPA 
will publish that generic name on the public Inventory. If the 
submitter's proposed generic name is not acceptable, EPA will notify the 
submitter of EPA's choice of a generic name. Thirty days after this 
notification, EPA will place the chosen generic name on the public 
Inventory.



Sec. 720.87  Categories or proposed categories of uses of a new chemical substance.

    (a) A person who submits information to EPA under this part on the 
categories or proposed categories of use of a new chemical substance may 
assert a claim of confidentiality for this information.
    (b) A submitter that asserts such a claim must:
    (1) Report the categories or proposed categories of use of the 
chemical substance.
    (2) Provide, in nonconfidential form, a description of the uses that 
is only as generic as necessary to protect the confidential business 
information. The generic use description will be included in the Federal 
Register notice described in Sec. 720.70.
    (c) The person must submit the information required by paragraph (b) 
of this section in the manner specified in the notice form.

[[Page 117]]



Sec. 720.90  Data from health and safety studies.

    (a) Information other than specific chemical identity. Except as 
provided in paragraph (b) of this section, EPA will deny any claim of 
confidentiality with respect to information included in a health and 
safety study, unless the information would disclose confidential 
business information concerning:
    (1) Processes used in the manufacture or processing of a chemical 
substance or mixture.
    (2) In the case of a mixture, the portion of the mixture comprised 
by any of the chemical substances in the mixture.
    (3) Information which is not in any way related to the effects of a 
substance on human health or the environment, such as the name of the 
submitting company, cost or other financial data, product development or 
marketing plans, and advertising plans, for which the person submits a 
claim of confidentiality in accordance with Sec. 720.80.
    (b) Specific chemical identity--(1) Claims applicable to period 
prior to commencement of manufacture. A claim of confidentiality for the 
period prior to commencement of manufacture or import for the chemical 
identity of a chemical substance for which a health and safety study was 
submitted must be asserted in conjunction with a claim asserted under 
Sec. 720.85(a).
    (2) Claims applicable to period after commencement of manufacture or 
import for commercial purposes. To maintain the confidential status of 
the chemical identity of a chemical substance for which a health and 
safety study was submitted after commencement of manufacture or import, 
the claim must be reasserted and substantiated in conjunction with a 
claim under Sec. 720.85(b). In addition to the questions set forth in 
Sec. 720.85(b)(3)(iv) of this part, the submitter must answer the 
following questions:
    (i) Would disclosure of the chemical identity disclose processes 
used in the manufacture or processing of a chemical substance or 
mixture? Describe how this would occur. In responding to the question in 
Sec. 720.85(b)(3)(iv)(A), explain what harmful competitive effects would 
occur from disclosure of this process information.
    (ii) Would disclosure of the chemical identity disclose the portion 
of a mixture comprised by any of the substances in the mixture? Describe 
how this would occur. In responding to the question in 
Sec. 720.85(b)(3)(iv)(A), explain what harmful competitive effects would 
occur from disclosure of this information.
    (iii) Do you assert that disclosure of the chemical identity is not 
necessary to interpret any of the health and safety studies you have 
submitted? If so, explain how a less specific identity would be 
sufficient to interpret the studies.
    (c) Denial of confidentiality claim. EPA will deny a claim of 
confidentiality for chemical identity under paragraph (b) of this 
section, unless:
    (1) The information would disclose processes used in the manufacture 
or processing of a chemical substance or mixture.
    (2) In the case of a mixture, the information would disclose the 
portion of the mixture comprised by any of the substances in the 
mixture.
    (3) The specific chemical identity is not necessary to interpret a 
health and safety study.
    (d) Use of generic names. When EPA discloses a health and safety 
study containing a specific chemical identity, which the submitter has 
claimed confidential, and if the Agency has not denied the claim under 
paragraph (c) of this section, EPA will identify the chemical substance 
by the generic name selected under Sec. 720.85.

[48 FR 21742, May 13, 1983, as amended at 58 FR 34204, June 23, 1993]



Sec. 720.95  Public file.

    All information submitted with a notice, including any health and 
safety study and other supporting documentation, will become part of the 
public file for that notice, unless such materials are claimed 
confidential. In addition, EPA may add materials to the public file, 
subject to subpart E of this part. Any of the nonconfidential material 
described in this subpart will be available for public inspection in the 
Non-Confidential Information Center

[[Page 118]]

(NCIC) (7407), Office of Pollution Prevention and Toxics, U.S. 
Environmental Protection Agency, Room B-607 NEM, 401 M Street, SW., 
Washington, DC, 20460, between the hours of 12 p.m. and 4 p.m. weekdays 
excluding legal holidays.

[48 FR 21742, May 13, 1983, as amended at 53 FR 12523, Apr. 15, 1988; 60 
FR 16311, Mar. 29, 1995; 60 FR 34464, July 3, 1995]



            Subpart F--Commencement of Manufacture or Import



Sec. 720.102  Notice of commencement of manufacture or import.

    (a) Applicability. Any person who commences the manufacture or 
import of a new chemical substance for a nonexempt commercial purpose 
for which that person previously submitted a section 5(a) notice under 
this part must submit a notice of commencement of manufacture or import.
    (b) When to report. (1) If manufacture or import for commercial 
purposes begins on or after the effective date of this rule, the 
submitter must submit the notice to EPA on, or no later than 30 calendar 
days, after the first day of such manufacture or import.
    (2) If manufacture or import for commercial purposes began or will 
begin before the effective date of this rule, the submitter must submit 
the notice by the effective date of this rule.
    (c) Information to be reported on form. (1) The notice must be 
submitted on EPA (Form 7710-56), which is available from the 
Environmental Assistance Division (7408), Office of Pollution Prevention 
and Toxics, Environmental Protection Agency, 401 M St., SW., Washington, 
DC 20460. The form must be signed and dated by an authorized official. 
All information specified on the form must be provided. The notice must 
contain the following information:
    (i) The specific chemical identity of the PMN substance.
    (ii) A generic chemical name (if the chemical identity is claimed as 
confidential by the submitter).
    (iii) The premanufacture notice (PMN) number assigned by EPA.
    (iv) The date of commencement for the submitter's manufacture or 
import for a non-exempt commercial purpose (indicating whether the 
substance was initially manufactured in the United States or imported). 
The date of commencement is the date of completion of non-exempt 
manufacture of the first amount (batch, drum, etc.) of new chemical 
substance identified in the submitter's PMN. For importers, the date of 
commencement is the date the new chemical substance clears United States 
customs.
    (v) The name and address of the submitter.
    (vi) The name of the authorized official.
    (vii) The name and telephone number of a technical contact in the 
United States.
    (viii) The address of the site where commencement of manufacture 
occurred.
    (ix) Clear indications of whether the chemical identity, submitter 
identity, and/or other information are claimed as confidential by the 
submitter.
    (2) If the submitter claims the chemical identity confidential, and 
wants the identity to be listed on the confidential portion of the 
Inventory, the claim must be reasserted and substantiated in accordance 
with Sec. 720.85(b). Otherwise, EPA will list the specific chemical 
identity on the public Inventory. Submitters who did not claim the 
chemical identity, submitter identity, or other information to be 
confidential in the PMN cannot claim this information as confidential in 
the notice of commencement.
    (d) Where to submit. Notices of commencement of manufacture or 
import should be submitted to the Document Control Office (7407), Office 
of Pollution Prevention and Toxics, U.S. Environmental Protection 
Agency, Room G-099, 401 M St., SW., Washington, DC., 20460.

(Approved by the Office of Management and Budget under control number 
2070-0012)

[48 FR 21742, May 13, 1983, as amended at 48 FR 41140, Sept. 13, 1983; 
51 FR 15103, Apr. 22, 1986; 53 FR 12523, Apr. 15, 1988; 60 FR 16311, 
Mar. 29, 1995; 60 FR 34464, July 3, 1995]

[[Page 119]]



                  Subpart G--Compliance and Inspections



Sec. 720.120  Compliance.

    (a) Failure to comply with any provision of this part is a violation 
of section 15 of the Act (15 U.S.C 2614).
    (b) A person who manufactures or imports a new chemical substance 
before a notice is submitted and the notice review period expires is in 
violation of section 15 of the Act even if that person was not requied 
to submit the notice under Sec. 720.22.
    (c) Using for commercial purposes a chemical substance or mixture 
which a person knew or had reason to know was manufactured, processed, 
or distributed in commerce in violation of section 5 of this rule is a 
violation of section 15 of the Act (15 U.S.C. 2614).
    (d) Failure or refusal to establish and maintain records or to 
permit access to or copying of records, as required by the Act, is a 
violation of section 15 of the Act (15 U.S.C. 2614).
    (e) Failure or refusal to permit entry or inspection as required by 
section 11 is a violation of section 15 of the Act (15 U.S.C. 2614).
    (f) Violators may be subject to the civil and criminal penalties in 
section 16 of the Act (15 U.S.C. 2615) for each violation. Persons who 
submit materially misleading or false information in connection with the 
requirements of any provision of this rule may be subject to penalties 
calculated as if they never filed their notices.
    (g) EPA may seek to enjoin the manufacture or processing of a 
chemical substance in violation of this rule or act to seize any 
chemical substance manufactured or processed in violation of this rule 
or take other actions under the authority of section 7 of this Act (15 
U.S.C. 2606) or section 17 or this Act (15 U.S.C. 2616).



Sec. 720.122  Inspections.

    EPA will conduct inspections under section 11 of the Act to assure 
compliance with section 5 of the Act and this rule, to verify that 
information submitted to EPA under this rule is true and correct, and to 
audit data submitted to EPA under this rule.