[Title 21 CFR 178.3297]
[Code of Federal Regulations (annual edition) - April 1, 1996 Edition]
[Title 21 - FOOD AND DRUGS]
[Chapter I - FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED)]
[Subchapter B - FOOD FOR HUMAN CONSUMPTION]
[Part 178 - INDIRECT FOOD ADDITIVES: ADJUVANTS, PRODUCTION AIDS, AND SANITIZERS]
[Subpart D - Certain Adjuvants and Production Aids]
[Sec. 178.3297 - Colorants for polymers.]
[From the U.S. Government Publishing Office]




  21
  FOOD AND DRUGS
  3
  1996-04-01
  1996-04-01
  false
  Colorants for polymers.
  178.3297
  Sec. 178.3297
  
    FOOD AND DRUGS
    FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED)
    FOOD FOR HUMAN CONSUMPTION
    INDIRECT FOOD ADDITIVES: ADJUVANTS, PRODUCTION AIDS, AND SANITIZERS
    Certain Adjuvants and Production Aids
  


Sec. 178.3297  Colorants for polymers.

    The substances listed in paragraph (e) of this section may be safely 
used as colorants in the manufacture of articles or components of 
articles intended for use in producing, manufacturing, packing, 
processing, preparing, treating, packaging, transporting, or holding 
food, subject to the provisions and definitions set forth in this 
section:
    (a) The term colorant means a dye, pigment, or other substance that 
is used to impart color to or to alter the color of a food-contact 
material, but that does not migrate to food in amounts that will 
contribute to that food any color apparent to the naked eye. For the 
purpose of this section, the term ``colorant'' includes substances such 
as optical brighteners and fluorescent whiteners, which may not 
themselves be colored, but whose use is intended to affect the color of 
a food-contact material.
    (b) The colorant must be used in accordance with current good 
manufacturing practice, including use levels which are not in excess of 
those reasonably required to accomplish the intended coloring effect.
    (c) Colorants in this section must conform to the description and 
specifications indicated. If a polymer described in this section is 
itself the subject of a regulation promulgated under section 409 of the 
Federal Food, Drug, and Cosmetic Act, it shall also comply with any 
specifications and limitations prescribed by that regulation. Extraction 
testing guidelines to conduct studies for additional uses of colorants 
under this section are available from the Food and Drug Administration 
free of charge from the Center for Food Safety and Applied Nutrition, 
(HFS-200) Food and Drug Administration, 200 C St. SW., Washington, DC 
20204.
     (d) Color additives and their lakes listed for direct use in foods, 
under the provisions of the color additive regulations in parts 73, 74, 
81, and 82 of this chapter, may also be used as colorants for food-
contact polymers.
    (e) List of substances:

------------------------------------------------------------------------
                Substances                           Limitations        
------------------------------------------------------------------------
Aluminum..................................                              
Aluminum hydrate..........................                              
Aluminum and potassium silicate (mica)....                              
Aluminum mono-, di-, and tristearate......                              
Aluminum silicate (China clay)............                              
4-[[5-[[[4-(Aminocarbonyl) phenyl]          For use at levels not to    
 amino]carbonyl]- 2-methoxyphenyl]azo]-N-    exceed 1 percent by weight 
 (5-chloro-2,4-dimethoxyphenyl)-3-hydroxy-   of polymers. The finished  
 2-naphthalene-carboxamide (C.I. Pigment     articles are to contact    
 Red 187, CAS Reg. No. 59487-23-9).          foods only under conditions
                                             of use B through H         
                                             described in Table 2 of    
                                             Sec.  176.170(c) of this   
                                             chapter.                   

[[Page 359]]

                                                                        
N-[4-(Aminocarbonyl)phenyl]-4-[[1-[[(2,3-   For use at levels not to    
 dihydro-2-oxo-1H-benzimidazol-5-            exceed 1 percent by weight 
 yl)amino]carbonyl]-2-                       of polymers. The finished  
 oxopropyl]azo]benzamide (C. I. Pigment      articles are to contact    
 Yellow 181, CAS Reg. No. 74441-05-7).       food only under conditions 
                                             of use B through H         
                                             described in Table 2 of    
                                             Sec.  176.170(c) of this   
                                             chapter.                   
Barium sulfate............................                              
Bentonite.................................                              
Bentonite, modified with 3-                                             
 dimethyldioctadecylammonium ion.                                       
4,4'-Bis(4-anilino-6-diethanolamine--triazin-2-ylamino)-2,2'-stilbene         fibers specified in Sec.   
 disulfonic acid, disodium salt.             177.2800 of this chapter.  
4,4'-Bis(4-anilino-6-methylethanolamine-        Do.                     
 -triazin-2-ylamino)-2,2'-                                     
 stilbene disulfonic acid, disodium salt.                               
Burnt umber...............................                              
Calcium carbonate.........................                              
Calcium silicate..........................                              
Calcium sulfate...........................                              
Carbon black (channel process, prepared by                              
 the impingement process from stripped                                  
 natural gas).                                                          
4-Chloro-2-[[5-hydroxy-3-methyl-1-(3-       For use at levels not to    
 sulfophenyl)-1H-pyrazol-4-yl]azo]-5-        exceed 0.3 percent by      
 methylbenzenesulfonic acid,calcium salt     weight of the finished     
 (1:1); (C. I. Pigment Yellow 191, CAS       polymers. The finished     
 Reg. No. 129423-54-7)..                     articles are to contact    
                                             food only under conditions 
                                             of use B through H as      
                                             described in Table 2 of    
                                             Sec.  176.170(c) of this   
                                             chapter.                   
 Chromium oxide green, Cr2 O3 (C.I.          For use only:              
 pigment green 17, C.I. No. 77288).           1. In olefin polymers     
                                             complying with Sec.        
                                             177.1520 of this chapter.  
                                              2. In repeat-use rubber   
                                             articles complying with    
                                             Sec.  177.2600 of this     
                                             chapter; total use is not  
                                             to exceed 10 percent by    
                                             weight of rubber articles. 
Cobalt aluminate..........................  For use only:               
                                              1. In resinous and        
                                             polymeric coatings         
                                             complying with Sec.        
                                             175.300 of this chapter.   
                                              2. Melamine-formaldehyde  
                                             resins in molded articles  
                                             complying with Sec.        
                                             177.1460 of this chapter.  
                                              3. Xylene-formaldehyde    
                                             resins condensed with 4-   
                                             4'isopropylidenediphenol-  
                                             epichlorohydrin epoxy      
                                             resins complying with Sec. 
                                             175.380 of this chapter.   
                                              4. Ethylene-vinyl acetate 
                                             copolymers complying with  
                                             Sec.  177.1350 of this     
                                             chapter.                   
                                              5. Urea-formaldehyde      
                                             resins in molded articles  
                                             complying with Sec.        
                                             177.1900 of this chapter.  
                                              6. At levels not to exceed
                                             5 percent by weight of all 
                                             polymers except those      
                                             listed under limitations 1 
                                             through 5 of this item. The
                                             finished articles are to   
                                             contact food under         
                                             conditions of use A through
                                             H described in Table 2 of  
                                             Sec.  176.170(c) of this   
                                             chapter.                   
Copper chromite black spinel (C.I. Pigment  For use at levels not to    
 Black 28, CAS Reg. No. 68186-91-4)..        exceed 5 percent by weight 
                                             of polymers. The finished  
                                             articles are to contact    
                                             food only under conditions 
                                             of use A through H as      
                                             described in Table 2 of    
                                             Sec.  176.170(c) of this   
                                             chapter.                   
D&C Red No. 7 and its lakes...............                              
Diatomaceous earth........................                              
4,4'-Diamino-[1,1'-bianthracene]-           For use at levels not to    
 9,9',10,10'-tetrone (CAS Reg. No. 4051-63-  exceed 1 percent by weight 
 2).                                         of polymers. The finished  
                                             articles are to contact    
                                             food only under conditions 
                                             of use B through H         
                                             described in Table 2 of    
                                             Sec.  176.170(c) of this   
                                             chapter.                   
5-[(2,3-Dihydro-6-methyl-2-oxo-1H-          For use at levels not to    
 benzimidazol-5-yl)azo]-2,4,6(1H, 3H, 5H)-   exceed 1 percent by weight 
 pyrimidinetrione (CAS Reg. No. 72102-84-    of polymers. The finished  
 2).                                         articles are to contact    
                                             food only under conditions 
                                             of use B through H         
                                             described in Table 2 of    
                                             Sec.  176.170(c) of this   
                                             chapter.                   
3,3'-[(2,5-Dimethyl-1,4-                    For use at levels not to    
 phenylene)bis[imino(1-acetyl-2-oxo-2,1-     exceed 1 percent by weight 
 ethanediyl)azo]]bis[4-chloro-N-(5-chloro-   of polymers. The finished  
 2-methylphenyl)-benzamide] (CAS Reg. No.    articles are to contact    
 5280-80-8).                                 food only under conditions 
                                             of use B through H         
                                             described in Table 2 of    
                                             Sec.  176.170(c) of this   
                                             chapter.                   
3,3'-[(2,5-Dimethyl-1,4-                    For use at levels not to    
 phenylene)bis[imino-carbonyl(2-hydroxy-     exceed 1 percent by weight 
 3,1-naphthalenediyl) azo]] bis(4-           of polymers. The finished  
 methylbenzoic acid), bis(2-chloroethyl)     articles are to contact    
 ester (CAS Reg. No. 68259-05-2)..           food only under conditions 
                                             of use B through H         
                                             described in Table 2 of    
                                             Sec.  176.170(c) of this   
                                             chapter.                   

[[Page 360]]

                                                                        
2,2'-[1,2-Ethanediylbis(oxy-2,1-            For use at levels not to    
 phenyleneazo)]bis[N-(2,3-dihydro-2-oxo-1H-  exceed 1.0 percent by      
 benzimidazol-5-yl)]-3-oxo-butanamide        weight of polymers. The    
 (C.I. Pigment Yellow 180, CAS Reg. No.      finished articles are to   
 77804-81-0).                                contact food only under    
                                             conditions of use B through
                                             G described in Table 2 of  
                                             Sec.  176.170(c) of this   
                                             chapter.                   
2,2'-(1,2-Ethenediyldi-4,1-phenylene)       For use as an optical       
 bis(benzoxazole) (CAS Reg. No. 1533-45-5).  brightener for all polymers
                                             at a level not to exceed   
                                             0.025 percent by weight of 
                                             polymer. The finished      
                                             polymer shall contact foods
                                             only of the types          
                                             identified in Table 1 of   
                                             Sec.  176.170(c) of this   
                                             chapter, under categories  
                                             I, II, IV-B, VI-A, VI-B,   
                                             VII-B, and VIII at         
                                             temperatures not to exceed 
                                             275 F.                     
Iron oxides...............................                              
Kaolin-modified, produced by treating       For use only in olefin      
 kaolin with a reaction product of           polymers complying with    
 isopropyl titanate and oleic acid in        Sec.  177.1520 of this     
 which 1 mole of isopropyl titanate is       chapter at levels not to   
 reacted with 1 to 2 moles of oleic acid.    exceed 40 percent by weight
 The reaction product will not exceed 8      of olefin polymer.         
 percent of the modified kaolin. The oleic                              
 acid used shall meet the requirements                                  
 specified in Sec.  172.860 of this                                     
 chapter.                                                               
Magnesium oxide...........................                              
Magnesium silicate (talc).................                              
7-(2H-Naphtho[1,2-d]triazol-2-yl)-3-        For use as an optical       
 phenylcoumarin (CAS Reg. No. 3333-62-8)     brightener only in:        
 having a melting point of 250  deg.C to      1. Olefin polymers        
 251  deg.C and a nitrogen content of 10.7   complying with Sec.        
 to 11.2 percent.                            177.1520 of this chapter   
                                             only at levels such that   
                                             the product of             
                                             concentration of the       
                                             optical brightener         
                                             (expressed in parts per    
                                             million by weight of the   
                                             olefin polymer) multiplied 
                                             by the thickness of the    
                                             olefin polymer (expressed  
                                             in thousandths of an inch  
                                             and limited to no more than
                                             0.400 inch) shall not      
                                             exceed 500; provided that  
                                             the level of the brightener
                                             shall not exceed 20 parts  
                                             per million by weight of   
                                             the olefin polymer, and    
                                             further that the olefin    
                                             polymers shall comply with 
                                             specifications for items   
                                             1.1, 2.1, 3.1, 3.3, and 4  
                                             of Sec.  177.1520(c) of    
                                             this chapter. The polymer  
                                             may be used under the      
                                             conditions described in    
                                             Sec.  176.170(c) of this   
                                             chapter, Table 2, under    
                                             conditions of use E, F, and
                                             G.                         
                                              2. Polyethylene           
                                             terephthalate specified in 
                                             Sec.  177.2800(d)(5)(i) of 
                                             this chapter at a level not
                                             to exceed 0.035 percent by 
                                             weight of the finished     
                                             fibers.                    
1,1-[(6-Phenyl-1,3,5-triazine-2,4-          For use at levels not to    
 diyl)diimino]bis-9,10-anthracenedione       exceed 0.25 percent by     
 (CAS Reg. No. 4118-16-5).                   weight of polyethylene     
                                             phthalate polymers that    
                                             comply with Sec.  177.1630 
                                             of this chapter. The       
                                             finished articles are to   
                                             contact food only under    
                                             conditions of use E, F, and
                                             G described in table 2,    
                                             Sec.  176.170(c) of this   
                                             chapter, except, when such 
                                             articles are used with food
                                             types III, IV-A, and V,    
                                             described in table 1, Sec. 
                                             176.170(c) of this chapter,
                                             the finished articles are  
                                             to contact food only under 
                                             conditions of use D, E, F, 
                                             and G.                     
Phthalocyanine blue (C.I. pigment blue 15,                              
 15:1, 15:2, 15:3, and 15:4; C.I. No.                                   
 74160; CAS Reg. No. 147-14-8).                                         
Phthalocyanine green (C.I. pigment green                                
 7, C.I. No. 74260).                                                    
C.I. Pigment red 38 (C.I. No. 21120)......  For use only in rubber      
                                             articles for repeated use  
                                             complying with Sec.        
                                             177.2600 of this chapter;  
                                             total use is not to exceed 
                                             10 percent by weight of    
                                             rubber article.            
Quinacridone red (C.I. Pigment violet 19,                               
 C.I. No. 73900).                                                       
Sienna (raw and burnt)....................                              
Silica....................................                              
4,5,6,7-Tetrachloro-2-[2-(4,5,6,7-          For use only at levels not  
 tetrachloro-2,3-dihydro-1,3-dioxo-1H-       to exceed 1 percent by     
 inden-2-yl)-8-quinolinyl]-1H-isoindole-     weight of polymers. The    
 1,3(2H)-dione (C. I. Pigment Yellow 138,    finished articles are to   
 CAS Reg. No.30125-47-4)..                   contact food only under    
                                             conditions of use C through
                                             H, as described in Table 2 
                                             of Sec.  176.170(c) of this
                                             chapter; provided further  
                                             that the finished articles 
                                             shall not be filled at     
                                             temperatures exceeding 158 
                                             F (70 C).                  
2,2'-(2,5-Thiophenediyl)-bis (5-tert-       For use as an optical       
 butylbenzoxazole) (CAS Reg. No. 7128-64-    brightener only:           
 5).                                        1. At levels not to exceed  
                                             0.05 percent by weight of  
                                             the following polymers:    
                                             olefin polymers complying  
                                             with Sec.  177.1520(c) of  
                                             this chapter, item 2.1,    
                                             2.3, 3.1, 3.3, or 4;       
                                             polystyrene and            
                                             rubbermodified polystyrene 
                                             complying with Sec.        
                                             177.1640 of this chapter;  
                                             and polyvinyl chloride. The
                                             finished polymers shall    
                                             contact foods only of the  
                                             types identified in Table  
                                             1, Sec.  176.170(c) of this
                                             chapter, under Categories  
                                             I, II, IV-B, VI-A, VI-B,   
                                             and VIII under conditions  
                                             of use E, F, and G         
                                             described in Table 2 of    
                                             Sec.  176.170(c) of this   
                                             chapter.                   
                                            2. At levels not to exceed  
                                             0.05 percent by weight of  
                                             polypropylene complying    
                                             with Sec.  177.1520(c) of  
                                             this chapter, item 1.1,    
                                             1.2, or 1.3. The finished  
                                             polymer shall contact foods
                                             only of the types          
                                             identified in Table 1, Sec.
                                              176.170(c) of this        
                                             chapter, under Categories  
                                             I, II, IV-B, VI, VII-B, and
                                             VIII under conditions of   
                                             use A through H described  
                                             in Table 2 of Sec.         
                                             176.170(c) of this chapter.

[[Page 361]]

                                                                        
                                            3. At levels not to exceed  
                                             0.01 percent by weight of  
                                             polypropylene complying    
                                             with Sec.  177.1520(c) of  
                                             this chapter, item 1.1,    
                                             1.2, or 1.3. The finished  
                                             polymer shall contact foods
                                             only of the types          
                                             identified in Table 1, Sec.
                                              176.170(c) of this        
                                             chapter, under Categories  
                                             III, IV-A, V, VII-A, and IX
                                             under conditions of use A  
                                             through H described in     
                                             Table 2 of Sec.  176.170(c)
                                             of this chapter.           
                                            4 At levels not to exceed   
                                             0.01 percent by weight of  
                                             polyoxymethylene complying 
                                             with Sec.  177.2480 of this
                                             chapter.                   
                                            5. At levels not to exceed  
                                             0.015 percent by weight of 
                                             polycarbonate resins       
                                             complying with Sec.        
                                             177.1580 of this chapter.  
                                             The finished polymer shall 
                                             contact foods of the types 
                                             identified in Table 1 of   
                                             Sec.  176.170(c) of this   
                                             chapter, under categories, 
                                             I, II, IV-B, VI-B, and VIII
                                             under conditions of use B  
                                             through H described in     
                                             Table 2 of Sec.  176.170(c)
                                             of this chapter.           
Titanium dioxide..........................                              
Titanium dioxide-barium sulfate...........                              
Titanium dioxide-magnesium silicate.......                              
Ultramarines..............................  As identified in Sec.       
                                             73.2725 of this chapter.   
Zinc carbonate............................  For use only:               
                                              1. In resinous and        
                                             polymeric coatings         
                                             complying with Sec.        
                                             175.300 of this chapter.   
                                              2. Melamineformaldehyde   
                                             resins in molded articles  
                                             complying with Sec.        
                                             177.1460 of this chapter.  
                                              3. Xylene-formaldehyde    
                                             resins condensed with 4-4'-
                                             isopropylidene diphenol-   
                                             epichlorohydrin epoxy      
                                             resins complying with Sec. 
                                             175.380 of this chapter.   
                                              4. Ethylene-vinyl acetate 
                                             copolymers complying with  
                                             Sec.  177.1350 of this     
                                             chapter.                   
                                              5. Urea-formaldehyde      
                                             resins in molded articles  
                                             complying with Sec.        
                                             177.1900 of this chapter.  
Zinc chromate.............................  For use only in rubber      
                                             articles for repeated use  
                                             complying with Sec.        
                                             177.2600 of this chapter;  
                                             total use is not to exceed 
                                             10 percent by weight of    
                                             rubber article.            
Zinc oxide................................  For use only:               
                                              1. In resinous and        
                                             polymeric coatings         
                                             complying with Sec.        
                                             175.300 of this chapter.   
                                              2. Melamine-formaldehyde  
                                             resins in molded articles  
                                             complying with Sec.        
                                             177.1460 of this chapter.  
                                              3. Xylene-formaldehyde    
                                             resins condensed with 4-4'-
                                             isopropylidene-diphenol-   
                                             epichlorohydrin epoxy      
                                             resins complying with Sec. 
                                             175.380 of this chapter.   
                                              4. Ethylene-vinyl acetate 
                                             copolymers complying with  
                                             Sec.  177.1350 of this     
                                             chapter.                   
                                              5. Urea-formaldehyde      
                                             resins in molded articles  
                                             complying with Sec.        
                                             177.1900 of this chapter.  
Zinc sulfide..............................  For use at levels not to    
                                             exceed 10 percent by       
                                             weight.                    
------------------------------------------------------------------------

    [48 FR 46774, 46775, Oct. 14, 1983, as amended at 51 FR 7551, Mar. 
5, 1986; 51 FR 19168, May 28, 1986; 51 FR 23535, June 30, 1986; 53 FR 
52132, Dec. 27, 1988; 54 FR 21053, May 16, 1989; 54 FR 24898, June 12, 
1989; 54 FR 35875, Aug. 30, 1989; 55 FR 3585, Feb. 2, 1990; 55 FR 12344, 
Apr. 3, 1990; 55 FR 18721, May 4, 1990; 55 FR 31827, Aug. 6, 1990; 56 FR 
42933, Aug. 30, 1991; 56 FR 65782, Dec. 18, 1991; 58 FR 17514, Apr. 5, 
1993; 58 FR 67323, Dec. 21, 1993; 59 FR 3654, Jan. 26, 1994; 59 FR 5705, 
Feb. 8, 1994; 59 FR 10065, 10066, Mar. 3, 1994; 60 FR 31244, June 14, 
1995; 60 FR 39648, Aug. 3, 1995; 61 FR 2116, Jan. 25, 1996; 61 FR 14246, 
Apr. 1, 1996; 61 FR 14481, Apr. 2, 1996]