[Congressional Bills 119th Congress]
[From the U.S. Government Publishing Office]
[S. 5258 Introduced in Senate (IS)]

<DOC>






119th CONGRESS
  2d Session
                                S. 5258

  To amend title XI of the Social Security Act to establish a payment 
model to reimburse providers for furnishing comprehensive breast cancer 
    risk assessments and developing personalized screening and risk-
                reduction plans, and for other purposes.


_______________________________________________________________________


                   IN THE SENATE OF THE UNITED STATES

                             August 5, 2026

 Mr. Cassidy (for himself and Ms. Murkowski) introduced the following 
  bill; which was read twice and referred to the Committee on Finance

_______________________________________________________________________

                                 A BILL


 
  To amend title XI of the Social Security Act to establish a payment 
model to reimburse providers for furnishing comprehensive breast cancer 
    risk assessments and developing personalized screening and risk-
                reduction plans, and for other purposes.

    Be it enacted by the Senate and House of Representatives of the 
United States of America in Congress assembled,

SECTION 1. SHORT TITLE.

    This Act may be cited as the ``Personalized Risk Evaluation For 
Effective Risk Reduction and Early Detection Screening Act'' or the 
``PREFERRED Screening Act''.

SEC. 2. CMI MODEL TO TEST REIMBURSING ELIGIBLE PROVIDERS FOR FURNISHING 
              COMPREHENSIVE BREAST CANCER RISK ASSESSMENTS AND 
              DEVELOPING PERSONALIZED SCREENING AND RISK REDUCTION 
              PLANS.

    Section 1115A of the Social Security Act (42 U.S.C. 1315a) is 
amended--
            (1) in subsection (b)(2)(A), by adding at the end the 
        following new sentence: ``The models selected under this 
        subparagraph shall include the model described in subsection 
        (h).''; and
            (2) by adding at the end the following new subsection:
    ``(h) Testing Reimbursing Providers for Furnishing Comprehensive 
Breast Cancer Risk Assessments and Developing Personalized Screening 
and Risk Reduction Plans.--
            ``(1) Purpose and establishment.--
                    ``(A) In general.--Not later than 2 years after the 
                date of enactment of this subsection, the Secretary 
                shall implement a payment model (referred to in this 
                subsection as the `Model') to reimburse eligible 
                providers (as defined in paragraph (11)) for furnishing 
                comprehensive breast cancer risk assessments to 
                eligible individuals (as defined in such paragraph), 
                and for developing personalized screening and risk-
                reduction plans based on such assessments.
                    ``(B) Purpose.--The purpose of the Model is to test 
                whether reimbursing eligible providers for furnishing 
                comprehensive breast cancer risk assessments and 
                developing personalized screening and risk-reduction 
                plans changes the furnishing of breast cancer screening 
                and risk-reduction services to eligible individuals.
                    ``(C) Beginning of model.--For purposes of this 
                subsection, the Model shall be treated as having begun 
                on the date on which the first eligible individual 
                receives a comprehensive breast cancer risk assessment 
                furnished under the Model.
                    ``(D) Notification requirement if there is a 
                delay.--If the Model has not begun by the date that is 
                2 years after the date of enactment of this subsection, 
                the Secretary shall notify the relevant committees of 
                the reasons for the delay and of the expected date on 
                which the Model will begin.
                    ``(E) Rule of construction.--Nothing in this 
                subsection shall be construed to require the Secretary 
                to establish the clinical efficacy of risk-stratified 
                breast cancer screening.
            ``(2) Comprehensive breast cancer risk assessments and 
        personalized screening and risk-reduction plans.--
                    ``(A) Comprehensive breast cancer risk 
                assessments.--
                            ``(i) In general.--A comprehensive breast 
                        cancer risk assessment described in paragraph 
                        (1) shall--
                                    ``(I) collect the information 
                                described in clause (ii);
                                    ``(II) using a validated risk 
                                model, produce an estimate of an 
                                eligible individual's 5-year risk of 
                                developing breast cancer, supplemented 
                                by the results of multigene panel 
                                testing and a polygenic risk score; and
                                    ``(III) on the basis of such 
                                estimate and the results of multigene 
                                panel testing, assign such eligible 
                                individual to a risk category. Such 
                                risk categories shall include at 
                                minimum a high-risk category and an 
                                elevated-risk category and be 
                                established by the Secretary.
                            ``(ii) Information collected.--The 
                        information described in this clause, with 
                        respect to an eligible individual, is--
                                    ``(I) the results of genetic 
                                testing, including multigene panel 
                                testing for the BRCA1, BRCA2, PALB2, 
                                CDH1, TP53, PTEN, STK11, ATM, and CHEK2 
                                genes and such other breast cancer 
                                susceptibility genes as the Secretary 
                                determines appropriate;
                                    ``(II) a polygenic risk score;
                                    ``(III) the family history of the 
                                eligible individual with respect to 
                                breast cancer and related cancers;
                                    ``(IV) breast density, as 
                                determined under mammographic imaging;
                                    ``(V) clinical and lifestyle risk 
                                factors; and
                                    ``(VI) such other information as 
                                the Secretary determines appropriate.
                    ``(B) Personalized screening and risk-reduction 
                plan.--A personalized screening and risk reduction plan 
                described in paragraph (1) shall include--
                            ``(i) recommendations regarding--
                                    ``(I) adjusted cancer screening 
                                frequency and modality (such as 
                                mammography, magnetic resonance imaging 
                                (referred to in this subsection as 
                                `MRI'), and ultrasounds) based on an 
                                individual's risk level;
                                    ``(II) referrals for enhanced 
                                surveillance imaging, including breast 
                                MRIs, for high-risk individuals (as 
                                defined in paragraph (11));
                                    ``(III) risk reduction counseling 
                                on modifiable factors, such as weight 
                                management, physical activity, and 
                                alcohol consumption;
                                    ``(IV) counseling for a high-risk 
                                individual regarding endocrine risk-
                                reducing medications, such as 
                                tamoxifen, raloxifene, and aromatase 
                                inhibitors;
                                    ``(V) referrals for genetic 
                                counseling following pathogenic, likely 
                                pathogenic, or uncertain significance 
                                findings based on test results; and
                                    ``(VI) when such individual should 
                                be reassessed based on changes in risk 
                                factors, updated risk models, or 
                                reclassification of genetic variants;
                            ``(ii) notifying first-degree relatives who 
                        may benefit from genetic testing; and
                            ``(iii) communicating the personalized 
                        screening and risk-reduction plan to the 
                        individual's primary care provider and 
                        integrating such plan into the individual's 
                        medical record.
            ``(3) Delivery approaches.--The Secretary shall ensure that 
        the Model allows eligible providers to furnish comprehensive 
        breast cancer risk assessments through--
                    ``(A) traditional in-person office visits; and
                    ``(B) remote means, including allowing such 
                providers to collect genetic testing specimens through 
                kits mailed to an eligible individual's home.
            ``(4) Site selection.--
                    ``(A) In general.--The Secretary shall ensure that 
                the eligible providers participating in the Model 
                include a mix of academic medical centers, community-
                based practices, and facilities serving rural 
                populations.
                    ``(B) Application.--An eligible provider seeking to 
                enroll in the Model shall submit to the Secretary an 
                application for enrollment containing such 
                requirements, at such time, and in such manner, as 
                specified by the Secretary.
                    ``(C) Selection of eligible providers.--In 
                selecting eligible providers to participate in the 
                Model, the Secretary shall prioritize such providers--
                            ``(i) located in the 10 States with the 
                        highest breast cancer mortality rate among 
                        women;
                            ``(ii) located in an area designated as a 
                        health professional shortage area under section 
                        332(a)(1)(A) of the Public Health Service Act;
                            ``(iii) located in a medically underserved 
                        area or that serve medically underserved 
                        populations (as defined in section 330(b)(3) of 
                        such Act); or
                            ``(iv) located in a rural area (as defined 
                        in section 1886(d)(2)(D)) whose population has 
                        limited access to genetic counseling services 
                        or comprehensive breast cancer risk 
                        assessments.
                    ``(D) Data sharing.--In selecting eligible 
                providers to participate in the Model, the Secretary 
                may give preference to eligible providers who use 
                laboratories that submit de-identified variant data, 
                including variants of uncertain significance, to the 
                ClinVar public database maintained by the National 
                Center for Biotechnology Information.
            ``(5) Payment.--
                    ``(A) In general.--The Secretary shall establish a 
                payment amount for the furnishing of a comprehensive 
                breast cancer risk assessment and personalized 
                screening and risk reduction plan under the Model.
                    ``(B) Considerations.--In determining the payment 
                amount described in subparagraph (A), the Secretary 
                shall consider--
                            ``(i) the clinical time and complexity of 
                        the services furnished;
                            ``(ii) the interpretation of genetic 
                        testing results, polygenic risk scores, and 
                        breast density data;
                            ``(iii) the time required for the 
                        development of personalized screening and risk 
                        reduction plans; and
                            ``(iv) comparable comprehensive assessment 
                        and prevention-planning services under the 
                        physician fee schedule under title XVIII.
                    ``(C) Adjustment.--The Secretary may adjust the 
                payment amount established under subparagraph (A) 
                during the period of the Model on the basis of the 
                evaluation described in paragraph (6)(A)(vi).
            ``(6) Evaluation.--The Secretary shall evaluate the Model 
        from claims data and from the personalized screening and risk-
        reduction plans developed under the Model by the following 
        measures that the Secretary shall stratify by age band:
                    ``(A) Primary measures.--The Secretary shall 
                evaluate--
                            ``(i) the proportion of eligible 
                        individuals who receive a comprehensive breast 
                        cancer risk assessment under the Model;
                            ``(ii) whether the services recommended in 
                        an eligible individual's personalized screening 
                        and risk-reduction plan have been furnished to 
                        such individual;
                            ``(iii) the extent to which screening 
                        mammography frequency and modality vary across 
                        the risk categories established under paragraph 
                        (2)(A)(i)(III);
                            ``(iv) breast MRI utilization among high-
                        risk individuals;
                            ``(v) utilization of endocrine risk-
                        reducing medications, such as tamoxifen, 
                        raloxifene, and aromatase inhibitors, among 
                        high-risk individuals and individuals assigned 
                        to an elevated risk category;
                            ``(vi) whether the payment amount is 
                        sufficient to sustain eligible provider 
                        participation in the Model; and
                            ``(vii) the number of eligible providers 
                        who continue to participate in the Model.
                    ``(B) Secondary measures.--The Secretary shall 
                evaluate--
                            ``(i) the total cost of care for breast 
                        cancer screening and treatment episodes among 
                        participating eligible individuals, benchmarked 
                        against national utilization and spending for 
                        individuals comparable to eligible individuals;
                            ``(ii) the projected cost-effectiveness of 
                        the Model over a 10-year and 20-year horizon, 
                        including the estimated value of cancers 
                        prevented, cancers detected at earlier stages, 
                        and screening procedures avoided;
                            ``(iii) the proportion of comprehensive 
                        breast cancer risk assessments that integrate 
                        each item of information described in paragraph 
                        (2)(A)(ii);
                            ``(iv) the rate at which personalized 
                        screening and risk reduction plans are 
                        developed and communicated to the primary care 
                        providers of eligible individuals;
                            ``(v) the average time from when an 
                        eligible individual first receives a 
                        comprehensive breast cancer risk assessment to 
                        the time such individual receives a 
                        personalized screening and risk reduction plan;
                            ``(vi) the rate at which eligible 
                        individuals adhere to the recommendations in 
                        their personalized screening and risk reduction 
                        plan;
                            ``(vii) whether there are any differences 
                        in the measures described in this subparagraph 
                        between different delivery approaches and 
                        eligible providers; and
                            ``(viii) reported outcomes of eligible 
                        individuals, including the satisfaction of 
                        eligible individuals with the personalized 
                        screening and risk reduction plan furnished to 
                        such individuals, the understanding of the 
                        personal risk level of eligible individuals, 
                        and the anxiety and decisional conflict of 
                        eligible individuals, measured using validated 
                        patient-reported outcome instruments.
                    ``(C) Exploratory measures.--The Secretary shall 
                evaluate, among participating eligible individuals--
                            ``(i) the rate of--
                                    ``(I) stage IIB or higher breast 
                                cancers; and
                                    ``(II) stage IIA breast cancers;
                            ``(ii) the rate of ductal carcinoma in situ 
                        (DCIS) detection; and
                            ``(iii) the proportion of breast cancers 
                        detected through screening compared to the 
                        number of breast cancers detected through 
                        symptomatic presentation.
            ``(7) Additional authority.--If the Secretary determines 
        that additional statutory authority is required to test or 
        expand the Model, not later than 180 days after making such 
        determination, the Secretary shall notify the Committee on 
        Finance of the Senate and the Committee on Ways and Means of 
        the House of Representatives.
            ``(8) Termination.--
                    ``(A) In general.--The Model shall terminate on the 
                date that is 7 years after the date on which the Model 
                begins, unless the Secretary determines that expansion 
                of the Model is appropriate under subsection (c).
                    ``(B) Authority.--The Secretary may not terminate 
                the Model under subsection (b)(3)(B) until after the 
                date on which the Secretary submits the interim report 
                described in paragraph (9)(A).
            ``(9) Reports.--
                    ``(A) Interim report.--Not later than the date that 
                is 3 years after the commencement of the Model, the 
                Secretary shall submit to the relevant committees, the 
                Director of the Agency for Healthcare Research and 
                Quality, and the United States Preventive Services Task 
                Force an interim report describing--
                            ``(i) the measures used to evaluate the 
                        Model under paragraph (6); and
                            ``(ii) the rate of laboratories used by 
                        eligible providers that submit de-identified 
                        variant data to the ClinVar public database 
                        maintained by the National Center for 
                        Biotechnology Information.
                    ``(B) Final report.--Not later than the date that 
                is 7 years after the commencement of the Model, the 
                Secretary shall submit to the relevant committees, the 
                Director of the Agency for Healthcare Research and 
                Quality, and the United States Preventive Services Task 
                Force a final report--
                            ``(i) describing the measures used to 
                        evaluate the Model under paragraph (6);
                            ``(ii) the rate of laboratories used by 
                        eligible providers that submit de-identified 
                        variant data to the ClinVar public database 
                        maintained by the National Center for 
                        Biotechnology Information; and
                            ``(iii) with recommendations regarding 
                        whether the model should be expanded or made 
                        permanent, including whether the Model should 
                        be expanded to individuals enrolled in a 
                        Medicare Advantage plan under part C of title 
                        XVIII.
                    ``(C) United states preventive services task 
                force.--If, after the date of enactment of this Act, 
                the United States Preventive Services Task Force issues 
                an updated recommendation addressing breast cancer risk 
                assessment or germline genetic testing, the Secretary 
                shall--
                            ``(i) evaluate the effect on such 
                        recommendation on the design and evaluation of 
                        the Model, including whether any modification 
                        of the Model is warranted; and
                            ``(ii) not later than 180 days after the 
                        United States Preventive Services Task Force 
                        issues such recommendation, submit to the 
                        relevant committees a report describing such 
                        evaluation.
            ``(10) Funding.--No additional funds are authorized to be 
        appropriated to carry out this subsection. The Secretary shall 
        carry out the Model using funds otherwise available under 
        subsection (f).
            ``(11) Definitions.--In this subsection:
                    ``(A) Eligible individual.--The term `eligible 
                individual' means an individual--
                            ``(i) entitled to, or enrolled for, 
                        benefits under part A of title XVIII, or 
                        enrolled for benefits under part B of such 
                        title, but not enrolled in a plan under part C 
                        of such title;
                            ``(ii) who has attained 40 years of age but 
                        has not attained 75 years of age;
                            ``(iii) who does not have end-stage renal 
                        disease; and
                            ``(iv) who is not receiving hospice care 
                        under title XVIII.
                    ``(B) Eligible provider.--
                            ``(i) In general.--The term `eligible 
                        provider' means--
                                    ``(I) a physician (as defined in 
                                section 1861(r)(1));
                                    ``(II) a certified nurse-midwife 
                                (as defined in section 1861(gg));
                                    ``(III) a nurse practitioner (as 
                                defined in section 1861(aa)(5)(A));
                                    ``(IV) a physician assistant (as 
                                defined in such section);
                                    ``(V) a genetic counselor who is 
                                certified by the American Board of 
                                Genetic Counseling or the American 
                                Board of Medical Genetics and Genomics; 
                                or
                                    ``(VI) any other qualified health 
                                professional determined appropriate by 
                                the Secretary.
                            ``(ii) Clarification.--An individual 
                        described in clause (i) shall be considered an 
                        eligible provider without regard to whether 
                        such individual is otherwise recognized as a 
                        supplier under title XVIII.
                    ``(C) High-penetrance gene.--The term `high-
                penetrance gene' means the BRCA1, BRCA2, PALB2, CDH1, 
                TP53, PTEN, or STK11 gene, and any such other gene as 
                the Secretary determines to confer comparable risk.
                    ``(D) High-risk individual.--The term `high-risk 
                individual' means an individual--
                            ``(i) whose 5-year risk of developing 
                        breast cancer, as estimated by a validated risk 
                        model, is 6 percent or greater;
                            ``(ii) who has a pathogenic variant in a 
                        high-penetrance gene; or
                            ``(iii) who possesses such other criteria 
                        that the Secretary determines to be 
                        appropriate, consistent with applicable 
                        clinical practice guidelines.
                    ``(E) Relevant committees.--The term `relevant 
                committees' means the Committee on Finance and the 
                Committee on Health, Education, Labor, and Pensions of 
                the Senate, the Committee on Ways and Means and the 
                Committee on Energy and Commerce of the House of 
                Representatives.
                    ``(F) Validated risk model.--The term `validated 
                risk model' means a model that--
                            ``(i) produces an estimate of an 
                        individual's 5-year risk of developing breast 
                        cancer; and
                            ``(ii) the Secretary determines has been 
                        validated in a population comparable to 
                        eligible individuals.''.
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