[Congressional Bills 119th Congress]
[From the U.S. Government Publishing Office]
[H.R. 8192 Introduced in House (IH)]
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119th CONGRESS
2d Session
H. R. 8192
To direct the Secretary of Health and Human Services to issue
guidelines for the purpose of addressing the problem of nitazene
overdoses, and for other purposes.
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IN THE HOUSE OF REPRESENTATIVES
April 2, 2026
Mr. Taylor introduced the following bill; which was referred to the
Committee on Energy and Commerce
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A BILL
To direct the Secretary of Health and Human Services to issue
guidelines for the purpose of addressing the problem of nitazene
overdoses, and for other purposes.
Be it enacted by the Senate and House of Representatives of the
United States of America in Congress assembled,
SECTION 1. SHORT TITLE.
This Act may be cited as the ``Nitazene Response Act''.
SEC. 2. ASSISTANCE IN RESPONDING TO NITAZENE OVERDOSES.
(a) Guidelines.--
(1) In general.--The Secretary of Health and Human Services
(in this section referred to as the ``Secretary'') shall issue
updated, evidence-based clinical guidelines (in this section
referred to as the ``guidelines'') for responding to nitazene
overdoses.
(2) Contents.--The guidelines shall contain--
(A) a description of best practices for responding
to potential nitazene overdoses, including protocols
for administering naloxone;
(B) guidance for emergency departments and
hospitals in responding to nitazene overdoses;
(C) guidance for rural and volunteer emergency
medical services systems in responding to nitazene
overdoses; and
(D) such other information as the Secretary
determines appropriate.
(3) Publication.--Not later than 180 days after the date of
enactment of this Act, the Secretary shall publish the
guidelines on the public internet website of the Department of
Health and Human Services.
(b) Report to Congress.--Not later than one year after the date of
enactment of this Act, the Secretary shall submit to Congress a report
containing the guidelines and a description of how the guidelines will
assist in addressing the problem of nitazene overdoses.
(c) Definitions.--In this section:
(1) Nitazene.--
(A) In general.--The term ``nitazene'' means
benzimidazole-opioids, including any substance
(including its salts, isomers, and salts of isomers)
that has a chemical structure that is substantially
similar to that of etonitazene or isotonitazene,
including--
(i) a benzimidazole core substituted at the
2-position with a benzyl or substituted benzyl
group;
(ii) a basic nitrogen-containing side chain
at the 1-position; and
(iii) exhibits agonist activity at the mu-
opioid receptor.
(B) Included substances.--The term ``nitazene''
includes, at a minimum, the following: etonitazene,
clonitazene, metonitazene, isotonitazene,
protonitazene, butonitazene, etodesnitazene,
flunitazene, N-pyrrolidino etonitazene, N-desethyl
isotonitazene, and N-piperidinyl etonitazene.
(2) Nitazene overdose.--The term ``nitazene overdose''
means an overdose involving nitazene or any other ultra-potent
synthetic opioid.
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