[Congressional Bills 104th Congress]
[From the U.S. Government Publishing Office]
[S. 1897 Introduced in Senate (IS)]







104th CONGRESS
  2d Session
                                S. 1897

  To amend the Public Health Service Act to revise and extend certain 
 programs relating to the National Institutes of Health, and for other 
                               purposes.


_______________________________________________________________________


                   IN THE SENATE OF THE UNITED STATES

                             June 21, 1996

 Mrs. Kassebaum (for herself, Mr. Kennedy, Mr. Jeffords, Mr. Pell, and 
 Mr. Hatfield) introduced the following bill; which was read twice and 
         referred to the Committee on Labor and Human Resources

_______________________________________________________________________

                                 A BILL


 
  To amend the Public Health Service Act to revise and extend certain 
 programs relating to the National Institutes of Health, and for other 
                               purposes.

    Be it enacted by the Senate and House of Representatives of the 
United States of America in Congress assembled,

SECTION 1. SHORT TITLE; REFERENCES; AND TABLE OF CONTENTS

    (a) Short Title.--This Act may be cited as the ``National 
Institutes of Health Revitalization Act of 1996''.
    (b) References.--Whenever in this Act an amendment is expressed in 
terms of an amendment to a section or other provision, the reference 
shall be considered to be made to a section or other provision of the 
Public Health Service Act (42 U.S.C. 201 et seq.).
    (c) Table of Contents.--The table of contents for this Act is as 
follows:

Sec. 1. Short title; references; and table of contents.
   TITLE I--PROVISIONS RELATING TO THE NATIONAL INSTITUTES OF HEALTH

Sec. 101. Director's discretionary fund.
Sec. 102. Children's vaccine initiative.
   TITLE II--PROVISIONS RELATING TO THE NATIONAL RESEARCH INSTITUTES

Sec. 201. Research on osteoporosis, Paget's disease, and related bone 
                            disorders.
Sec. 202. National Human Genome Research Institute.
Sec. 203. Increased amount of grant and other awards.
Sec. 204. Meetings of advisory committees and councils.
Sec. 205. Elimination or modification of reports.
               TITLE III--SPECIFIC INSTITUTES AND CENTERS

                 Subtitle A--National Cancer Institute

Sec. 301. Authorization of appropriations.
Sec. 302. DES study.
          Subtitle B--National Heart Lung and Blood Institute

Sec. 311. Authorization of appropriations.
   Subtitle C--National Institute of Allergy and Infectious Diseases

Sec. 321. Research and research training regarding tuberculosis.
Sec. 322. Terry Beirn community-based aids research initiative.
  Subtitle D--National Institute of Child Health and Human Development

Sec. 331. Research centers for contraception and infertility.
                Subtitle E--National Institute on Aging

Sec. 341. Authorization of appropriations.
     Subtitle F--National Institute on Alcohol Abuse and Alcoholism

Sec. 351. Authorization of appropriations.
Sec. 352. National alcohol research center.
              Subtitle G--National Institute on Drug Abuse

Sec. 361. Authorization of appropriations.
Sec. 362. Medication development program.
Sec. 363. Drug abuse research centers.
            Subtitle H--National Institute of Mental Health

Sec. 371. Authorization of appropriations.
           Subtitle I--National Center for Research Resources

Sec. 381. Authorization of appropriations.
Sec. 382. General clinical research centers.
Sec. 383. Enhancement awards.
Sec. 384. Waiver of limitations.
                Subtitle J--National Library of Medicine

Sec. 391. Authorization of appropriations.
Sec. 392. Increasing the cap on grant amounts.
                     TITLE IV--AWARDS AND TRAINING

Sec. 401. Medical scientist training program.
Sec. 402. Raise in maximum level of loan repayments.
Sec. 403. General loan repayment program.
Sec. 404. Clinical research assistance.
                 TITLE V--RESEARCH WITH RESPECT TO AIDS

Sec. 501. Comprehensive plan for expenditure of AIDS appropriations.
Sec. 502. Emergency AIDS discretionary fund.
                      TITLE VI--GENERAL PROVISIONS

              Subtitle A--Authority of the Director of NIH

Sec. 601. Authority of the director of NIH.
              Subtitle B--Office of Rare Disease Research

Sec. 611. Establishment of office for rare disease research.
                  Subtitle C--Certain Reauthorizations

Sec. 621. National research service awards.
Sec. 622. National Foundation for Biomedical Research.
                  Subtitle D--Miscellaneous Provisions

Sec. 631. Establishment of national fund for health research.
Sec. 632. Definition of clinical research.
Sec. 633. Senior Biomedical Research Service.
             Subtitle E--Repeals and Conforming Amendments

Sec. 641. Repeals and conforming amendments.

   TITLE I--PROVISIONS RELATING TO THE NATIONAL INSTITUTES OF HEALTH

SEC. 101. DIRECTOR'S DISCRETIONARY FUND.

    Section 402(i)(3) (42 U.S.C. 282(i)(3)) is amended by striking 
``$25,000,000'' and all that follows through the period and inserting 
``such sums as may be necessary for each of the fiscal years 1997 
through 1999.''.

SEC. 102. CHILDREN'S VACCINE INITIATIVE.

    Section 404B(c) (42 U.S.C. 283d(c)) is amended by striking 
``$20,000,000'' and all that follows through the period and inserting 
``such sums as may be necessary for each of the fiscal years 1997 
through 1999.''.

   TITLE II--PROVISIONS RELATING TO THE NATIONAL RESEARCH INSTITUTES

SEC. 201. RESEARCH ON OSTEOPOROSIS, PAGET'S DISEASE, AND RELATED BONE 
              DISORDERS.

    Section 409A(d) (42 U.S.C. 284e(d)) is amended by striking 
``$40,000,000'' and all that follows through the period and inserting 
``such sums as may be necessary for each of the fiscal years 1997 
through 1999.''.

SEC. 202. NATIONAL HUMAN GENOME RESEARCH INSTITUTE.

    (a) In General.--Part C of title IV (42 U.S.C. 285 et seq.) is 
amended by adding at the end thereof the following new subpart:

         ``Subpart 18--National Human Genome Research Institute

``SEC. 464Z. PURPOSE OF THE INSTITUTE.

    ``(a) In General.--The general purpose of the National Human Genome 
Research Institute is to characterize the structure and function of the 
human genome, including the mapping and sequencing of individual genes. 
Such purpose includes--
            ``(1) planning and coordinating the research goal of the 
        genome project;
            ``(2) reviewing and funding research proposals;
            ``(3) conducting and supporting research training;
            ``(4) coordinating international genome research;
            ``(5) communicating advances in genome science to the 
        public;
            ``(6) reviewing and funding proposals to address the 
        ethical, legal, and social issues associated with the genome 
        project (including legal issues regarding patents); and
            ``(7) planning and administering intramural, collaborative, 
        and field research to study human genetic disease.
    ``(b) Research.--The Director of the Institute may conduct and 
support research training--
            ``(1) for which fellowship support is not provided under 
        section 487; and
            ``(2) that is not residency training of physicians or other 
        health professionals.
    ``(c) Ethical, Legal, and Social Issues.--
            ``(1) In general.--Except as provided in paragraph (2), of 
        the amounts appropriated to carry out subsection (a) for a 
        fiscal year, the Director of the Institute shall make available 
        not less than 5 percent of amounts made available for 
        extramural research for carrying out paragraph (6) of such 
        subsection.
            ``(2) Nonapplication.--With respect to providing funds 
        under subsection (a)(6) for proposals to address the ethical 
        issues associated with the genome project, paragraph (1) shall 
        not apply for a fiscal year if the Director of the Institute 
        certifies to the Committee on Commerce of the House of 
        Representatives, and to the Committee on Labor and Human 
        Resources of the Senate, that the Director has determined that 
        an insufficient number of such proposals meet the applicable 
        requirements of sections 491 and 492.
    ``(d) Transfer.--
            ``(1) In general.--There are transferred to the National 
        Human Genome Research Institute all functions which the 
        National Center for Human Genome Research exercised before the 
        date of enactment of this subpart, including all related 
        functions of any officer or employee of the National Center for 
        Human Genome Research. The personnel employed in connection 
        with, and the assets, liabilities, contracts, property, 
        records, and unexpended balances of appropriations, 
        authorizations, allocations, and other funds employed, used, 
        held, arising from, available to, or to be made available in 
        connection with the functions transferred under this subsection 
        shall be transferred to the National Human Genome Research 
        Institute.
            ``(2) Legal documents.--All orders, determinations, rules, 
        regulations, permits, agreements, grants, contracts, 
        certificates, licenses, regulations, privileges, and other 
        administrative actions which have been issued, made, granted, 
        or allowed to become effective in the performance of functions 
        which are transferred under this subsection shall continue in 
effect according to their terms until modified, terminated, superseded, 
set aside, or revoked in accordance with law.
            ``(3) References.--References in any other Federal law, 
        Executive order, rule, regulation, or delegation of authority, 
        or any document of or relating to the National Center for Human 
        Genome Research shall be deemed to refer to the National Human 
        Genome Research Institute.
    ``(e) Authorization of Appropriations.--There are authorized to be 
appropriated to carry out this section, such sums as may be necessary 
for each of the fiscal years 1997 through 1999.''.
    (b) Conforming Amendments.--
            (1) Section 401(b) (42 U.S.C. 281(b)) is amended--
                    (A) in paragraph (1), by adding at the end thereof 
                the following new subparagraph:
            ``(R) The National Human Genome Research Institute.''; and
                    (B) in paragraph (2)--
                            (i) by striking subparagraph (D); and
                            (ii) by redesignating subparagraph (E) as 
                        subparagraph (D).
            (2) Subpart 3 of part E of title IV (42 U.S.C. 287c et 
        seq.) is repealed.

SEC. 203. INCREASED AMOUNT OF GRANT AND OTHER AWARDS.

    Section 405(b)(2)(B) (42 U.S.C. 284(b)(2)(B) is amended--
            (1) in clause (i), by striking ``$50,000'' and inserting 
        ``$100,000''; and
            (2) in clause (ii), by striking ``$50,000'' and inserting 
        ``$100,000''.

SEC. 204. MEETINGS OF ADVISORY COMMITTEES AND COUNCILS.

    (a) In General.--Section 406 (42 U.S.C. 284a) is amended--
            (1) in subsection (e), by striking ``, but at least three 
        times each fiscal year''; and
            (2) in subsection (h)(2)--
                    (A) in subparagraph (A)--
                            (i) in clause (iv), by adding ``and'' after 
                        the semicolon;
                            (ii) in clause (v), by striking ``; and'' 
                        and inserting a period; and
                            (iii) by striking clause (vi); and
                    (B) in subparagraph (B), by striking ``, except'' 
                and all that follows through ``year''.
    (b) President's Cancer Panel.--Section 415(a)(3) (42 U.S.C. 285a-
4(a)(3)) is amended by striking ``, but not less often than four times 
a year''.
    (c) Institute of Diabetes and Digestive and Kidney Diseases 
Interagency Coordinating Committees.--Section 429(b) (42 U.S.C. 285c-
3(b)) is amended by striking ``, but not less often than four times a 
year''.
    (d) Institute of Arthritis and Musculoskeletal and Skin Diseases 
Interagency Coordinating Committees.--Section 439(b) (42 U.S.C. 285d-
4(b)) is amended by striking ``, but not less often than four times a 
year''.
    (e) Institute on Deafness and Other Communication Disorders 
Interagency Coordinating Committees.--Section 464E(d) (42 U.S.C. 285m-
5(d)) is amended by striking ``, but not less often than four times a 
year''.
    (f) Institute of Nursing Research Advisory Council.--Section 
464X(e) (42 U.S.C. 285q-2(e)) is amended by striking ``, but at least 
three times each fiscal year''.
    (g) Center for Research Resources Advisory Council.--Section 480(e) 
(42 U.S.C. 287a(e)) is amended by striking ``, but at least three times 
each fiscal year''.
    (h) Application of FACA.--Part B of title IV (42 U.S.C. 284 et 
seq.) is amended by adding at the end thereof the following new 
section:

``SEC. 409B. APPLICATION OF FEDERAL ADVISORY COMMITTEE ACT.

    ``Notwithstanding any other provision of law, the provisions of the 
Federal Advisory Committee Act (5 U.S.C. Ap. 2) shall not apply to a 
scientific or technical peer review group, established under this 
title.''.

SEC. 205. ELIMINATION OR MODIFICATION OF REPORTS.

    (a) Public Health Service Act Reports.--The following provisions of 
the Public Health Service Act are repealed:
            (1) Section 403 (42 U.S.C. 283) relating to the biennial 
        report of the Director of the National Institutes of Health to 
        Congress and the President.
            (2) Subsection (c) of section 439 (42 U.S.C. 285d-4(c)) 
        relating to the annual report of the Arthritis and 
        Musculoskeletal Diseases Interagency Coordinating Committee and 
        the annual report of the Skin Diseases Interagency Coordinating 
        Committee.
            (3) Subsection (j) of section 442 (42 U.S.C. 285d-7(j)) 
        relating to the annual report of the National Arthritis and 
        Musculoskeletal and Skin Diseases Advisory Board.
            (4) Subsection (b) of section 494A (42 U.S.C. 289c-1(b)) 
        relating to the annual report of the Secretary of Health and 
        Human Services on health services research relating to alcohol 
        abuse and alcoholism, drug abuse, and mental health.
            (5) Subsection (b) of section 503 (42 U.S.C. 290aa-2(b)) 
        relating to the triennial report of the Secretary of Health and 
        Human Services to Congress.
    (b) Report on Disease Prevention.--Section 402(f)(3) (42 U.S.C. 
282(f)(3)) is amended by striking ``annually'' and inserting 
``biennially''.
    (c) Reports of the Coordinating Committees on Digestive Diseases, 
Diabetes Mellitus, and Kidney, Urologic and Hematologic Diseases.--
Section 429 (42 U.S.C. 285c-3) is amended by striking subsection (c).
    (d) Report of the Task Force on Aging Research.--Section 304 of the 
Home Health Care and Alzheimer's Disease Amendments of 1990 (42 U.S.C. 
242q-3) is repealed.
    (e) Sudden Infant Death Syndrome Research.--Section 1122 (42 U.S.C. 
300c-12) is amended--
            (1) in subsection (a)--
                    (A) by striking the subsection designation and 
                heading; and
                    (B) by striking ``of the type'' and all that 
                follows through ``adequate,'' and insert ``, such 
                amounts each year as will be adequate for research 
                which relates generally to sudden infant death 
                syndrome, including high-risk pregnancy and high-risk 
                infancy research which directly relates to sudden 
                infant death syndrome, and to the relationship of the 
                high-risk pregnancy and high-risk infancy research to 
                sudden infant death syndrome,''; and
            (2) by striking subsections (b) and (c).
    (f) U.S.-Japan Cooperative Medical Science Program.--Subsection (h) 
of section 5 of the International Health Research Act of 1960 is 
repealed.
    (g) Conforming Amendments.--Title IV is amended--
            (1) in section 404C(c) (42 U.S.C. 283e(c)), by striking 
        ``included'' and all that follows through the period and 
        inserting ``made available to the committee established under 
        subsection (e) and included in the official minutes of the 
        committee'';
            (2) in section 404E(d)(3)(B) (42 U.S.C. 283g(d)(3)(B)), by 
        striking ``for inclusion in the biennial report under section 
        403'';
            (3) in section 406(g) (42 U.S.C. 284a(g))--
                    (A) by striking ``for inclusion in the biennial 
                report made under section 407'' and inserting ``as it 
                may determine appropriate''; and
                    (B) by striking the second sentence;
            (4) in section 407 (42 U.S.C. 284b)--
                    (A) in the section heading, to read as follows:

                            ``reports''; and

                    (B) by striking ``shall prepare for inclusion in 
                the biennial report made under section 403 a biennial'' 
                and inserting ``may prepare a'';
            (5) in section 416(b) (42 U.S.C. 285a-5(b)) by striking 
        ``407'' and inserting ``402(f)(3)'';
            (6) in section 417 (42 U.S.C. 285a-6), by striking 
        subsection (e);
            (7) in section 423(b) (42 U.S.C. 285b-6(b)), by striking 
        ``407'' and inserting ``402(f)(3)'';
            (8) by striking section 433 (42 U.S.C. 285c-7);
            (9) in section 451(b) (42 U.S.C. 285g-3(b)), by striking 
        ``407'' and inserting ``402(f)(3)'';
            (10) in section 452(d) (42 U.S.C. 285g-4(d))--
                    (A) in paragraph (3)--
                            (i) in subparagraph (A), by striking ``(A) 
                        Not'' and inserting ``Not''; and
                            (ii) by striking subparagraph (B); and
                    (B) in the last sentence of paragraph (4), by 
                striking ``contained'' and all that follows through the 
                period and inserting ``transmitted to the Director of 
                NIH.'';
            (11) in section 464I(b) (42 U.S.C. 285n-1(b)), by striking 
        ``407'' and inserting ``402(f)(3)'';
            (12) in section 464M(b) (42 U.S.C. 285o-1)(b)), by striking 
        ``407'' and inserting ``402(f)(3)'';
            (13) in section 464S(b) (42 U.S.C. 285p-1(b)), by striking 
        ``407'' and inserting ``402(f)(3)'';
            (14) in section 464X(g) (42 U.S.C. 285q-2(g)) is amended--
                    (A) by striking ``for inclusion in the biennial 
                report made under section 464Y'' and inserting ``as it 
                may determine appropriate''; and
                    (B) by striking the second sentence;
            (15) in section 464Y (42 U.S.C. 285q-3)--
                    (A) in the section heading, to read as follows:

                            ``reports''; and

                    (B) by striking ``shall prepare for inclusion in 
                the biennial report made under section 403 a biennial'' 
                and inserting ``may prepare a'';
            (16) in section 480(g) (42 U.S.C. 287a(g))--
                    (A) by striking ``for inclusion in the biennial 
                report made under section 481'' and inserting ``as it 
                may determine appropriate''; and
                    (B) by striking the second sentence;
            (17) in section 481 (42 U.S.C. 287a-1)--
                    (A) in the section heading, to read as follows:

                            ``reports''; and

                    (B) by striking ``shall prepare for inclusion in 
                the biennial report made under section 403 a biennial'' 
                and inserting ``may prepare a'';
            (18) in section 486(d)(5)(B) (42 U.S.C. 287d(d)(5)(B)), by 
        striking ``for inclusion in the report required in section 
        403'';
            (19) in section 486B (42 U.S.C. 287d-2) by striking 
        subsection (b) and inserting the following new subsection:
    ``(b) Submission.--The Director of the Office shall submit each 
report prepared under subsection (a) to the Director of NIH.''; and
            (20) in section 492B(f) (42 U.S.C. 289a-2(f)), by striking 
        ``for inclusion'' and all that follows through the period and 
        inserting ``and the Director of NIH.''.

               TITLE III--SPECIFIC INSTITUTES AND CENTERS

                 Subtitle A--National Cancer Institute

SEC. 301. AUTHORIZATION OF APPROPRIATIONS.

    Section 417B (42 U.S.C. 286a-8) is amended--
            (1) in subsection (a), by striking ``$2,728,000,000'' and 
        all that follows through the period and inserting 
        ``$3,000,000,000 for fiscal year 1997, and such sums as may be 
        necessary for each of the fiscal years 1998 and 1999.'';
            (2) in subsection (b)--
                    (A) in paragraph (1)--
                            (i) in the first sentence of subparagraph 
                        (A), by striking ``$225,000,000'' and all that 
                        follows through the first period and inserting 
                        ``such sums as may be necessary for each of the 
                        fiscal years 1997 through 1999.''; and
                            (ii) in the first sentence of subparagraph 
                        (B), by striking ``$100,000,000'' and all that 
                        follows through the first period and inserting 
                        ``such sums as may be necessary for each of the 
                        fiscal years 1997 through 1999.''; and
                    (B) in the first sentence of paragraph (2), by 
                striking ``$75,000,000'' and all that follows through 
                the first period and inserting ``such sums as may be 
                necessary for each of the fiscal years 1997 through 
                1999.''; and
            (3) in the first sentence of subsection (c), by striking 
        ``$72,000,000'' and all that follows through the first period 
        and inserting ``such sums as may be necessary for each of the 
        fiscal years 1997 through 1999.''.

SEC. 302. DES STUDY.

    Section 403A(e) (42 U.S.C. 283a(e)) is amended by striking ``1996'' 
and inserting ``1999''.

          Subtitle B--National Heart Lung and Blood Institute

SEC. 311. AUTHORIZATION OF APPROPRIATIONS.

    Section 425 (42 U.S.C. 285b-8) is amended by striking 
``$1,500,000,000'' and all that follows through the period and 
inserting ``$1,600,000,000 for fiscal year 1997, and such sums as may 
be necessary for each of the fiscal years 1998 and 1999.''.

   Subtitle C--National Institute of Allergy and Infectious Diseases

SEC. 321. RESEARCH AND RESEARCH TRAINING REGARDING TUBERCULOSIS.

    Subpart 6 of part C of title IV is amended in the first section 
447(b) (42 U.S.C. 285f-2(b)) by striking ``$50,000,000'' and all that 
follows through the first period 1998'' and inserting such sums as may 
be necessary for each of the fiscal years 1997 through 1999.''.

SEC. 322. TERRY BEIRN COMMUNITY-BASED AIDS RESEARCH INITIATIVE.

    Section 2313(e) (42 U.S.C. 300cc-13(e)) is amended--
            (1) in paragraph (1), by striking ``1996'' and inserting 
        ``1999''; and
            (2) in paragraph (2), by striking ``1996'' and inserting 
        ``1999''.

  Subtitle D--National Institute of Child Health and Human Development

SEC. 331. RESEARCH CENTERS FOR CONTRACEPTION AND INFERTILITY.

    Section 452A(g) (42 U.S.C. 285g-5(g)) is amended by striking 
``$30,000,000'' and all that follows through the period and inserting 
``such sums as may be necessary for each of the fiscal years 1997 
through 1999.''.

                Subtitle E--National Institute on Aging

SEC. 341. AUTHORIZATION OF APPROPRIATIONS.

    Section 445I (42 U.S.C. 285e-11) is amended by striking 
``$500,000,000'' and all that follows through the period and inserting 
``$550,000,000 for fiscal year 1997, and such sums as may be necessary 
for each of the fiscal years 1998 and 1999.''.

     Subtitle F--National Institute on Alcohol Abuse and Alcoholism

SEC. 351. AUTHORIZATION OF APPROPRIATIONS.

    Section 464H(d)(1) (42 U.S.C. 285n(d)(1)) is amended by striking 
``300,000,000'' and all that follows through the period and inserting 
``$330,000,000 for fiscal year 1997, and such sums as may be necessary 
for each of the fiscal years 1998 and 1999.''.

SEC. 352. NATIONAL ALCOHOL RESEARCH CENTER.

    Section 464J(b) (42 U.S.C. 285n-2(b)) is amended--
            (1) by striking ``(b) The'' and inserting ``(b)(1) The'';
            (2) by striking the third sentence; and
            (3) by adding at the end thereof the following new 
        paragraph:
    ``(2) As used in paragraph (1), the terms `construction' and `cost 
of construction' include--
            ``(A) the construction of new buildings, the expansion of 
        existing buildings, and the acquisition, remodeling, 
        replacement, renovation, major repair (to the extent permitted 
        by regulations), or alteration of existing buildings, including 
        architects' fees, but not including the cost of the acquisition 
        of land or offsite improvements; and
            ``(B) the initial equipping of new buildings and of the 
        expanded, remodeled, repaired, renovated, or altered part of 
        existing buildings; except that
such term shall not include the construction or cost of construction of 
so much of any facility as is used or is to be used for sectarian 
instruction or as a place for religious worship.''.

              Subtitle G--National Institute on Drug Abuse

SEC. 361. AUTHORIZATION OF APPROPRIATIONS.

    Section 464L(d)(1) (42 U.S.C. 285o(d)(1)) is amended by striking 
``$440,000,000'' and all that follows through the period and inserting 
``$480,000,000 for fiscal year 1997, and such sums as may be necessary 
for each of the fiscal years 1998 and 1999.''.

SEC. 362. MEDICATION DEVELOPMENT PROGRAM.

    Section 464P(e) (42 U.S.C. 285o-4(e)) is amended by striking 
``$85,000,000'' and all that follows through the period and inserting 
``such sums as may be necessary for each of the fiscal years 1997 
through 1999''.

SEC. 363. DRUG ABUSE RESEARCH CENTERS.

    Section 464N(b) (42 U.S.C. 285o-2(b)) is amended--
            (1) by striking ``(b) The'' and inserting ``(b)(1) The'';
            (2) by striking the last sentence; and
            (3) by adding at the end thereof the following new 
        paragraph:
    ``(2) As used in paragraph (1), the terms `construction' and `cost 
of construction' include--
            ``(A) the construction of new buildings, the expansion of 
        existing buildings, and the acquisition, remodeling, 
        replacement, renovation, major repair (to the extent permitted 
        by regulations), or alteration of existing buildings, including 
        architects' fees, but not including the cost of the acquisition 
        of land or offsite improvements; and
            ``(B) the initial equipping of new buildings and of the 
        expanded, remodeled, repaired, renovated, or altered part of 
        existing buildings; except that
such term does not include the construction or cost of construction of 
so much of any facility as is used or is to be used for sectarian 
instruction or as a place for religious worship.''.

            Subtitle H--National Institute of Mental Health

SEC. 371. AUTHORIZATION OF APPROPRIATIONS.

    Section 464R(f)(1) (42 U.S.C. 285p(f)(1)) is amended by striking 
``$675,000,000'' and all that follows through the period and inserting 
``$750,000,000 for fiscal year 1997, and such sums as may be necessary 
for each of the fiscal years 1998 and 1999.''.

           Subtitle I--National Center for Research Resources

SEC. 381. AUTHORIZATION OF APPROPRIATIONS.

    (a) General Authorization.--Section 481A(h) (42 U.S.C. 287a-2(h)) 
is amended by striking ``$150,000,000'' and all that follows through 
the period and inserting ``such sums as may be necessary for each of 
the fiscal years 1997 through 1999.''.
    (b) Reservation for Construction of Regional Centers.--Section 
481B(a) (42 U.S.C. 287a-3(a)) is amended--
            (1) by striking ``shall'' and inserting ``may'';
            (2) by striking ``1994 through 1996'' and inserting ``1997 
        through 1999''; and
            (3) by striking ``$5,000,000'' and inserting ``such sums as 
        may be necessary for each such fiscal year''.

SEC. 382. GENERAL CLINICAL RESEARCH CENTERS.

    Part B of title IV (42 U.S.C. 284 et seq.), as amended by section 
205(h), is further amended by adding at the end thereof the following 
new section:

``SEC. 409C. GENERAL CLINICAL RESEARCH CENTERS.

    ``(a) Grants.--The Director of the National Center for Research 
Resources shall award grants for the establishment of general clinical 
research centers to provide the infrastructure for clinical research 
including clinical research training and career enhancement. Such 
centers shall support clinical studies and career development in all 
settings of the hospital or academic medical center involved.
    ``(b) Activities.--In carrying out subsection (a), the Director of 
NIH shall expand the activities of the general clinical research 
centers through the increased use of telecommunications and 
telemedicine initiatives.
    ``(c) Authorization of Appropriations.--There are authorized to be 
appropriated to make grants under subsection (a), such sums as may be 
necessary for each of the fiscal years 1996 and 1999.''.

SEC. 383. ENHANCEMENT AWARDS.

    Part B of title IV (42 U.S.C. 284 et seq.), as amended by sections 
205(h) and 382, is further amended by adding at the end thereof the 
following new section:

``SEC. 409D. ENHANCEMENT AWARDS.

    ``(a) Clinical Research Career Enhancement Award.--
            ``(1) In general.--The Director of the National Center for 
        Research Resources shall make grants (to be referred to as 
        `clinical research career enhancement awards') to support 
        individual careers in clinical research.
            ``(2) Applications.--An application for a grant under this 
        subsection shall be submitted by an individual scientist at 
        such time as the Director may require.
            ``(3) Limitations.--The amount of a grant under this 
        subsection shall not exceed $130,000 per year per grant. Grants 
        shall be for terms of 5 years. The Director shall award not 
        more than 20 grants in the first fiscal year in which grants 
        are awarded under this subsection. The total number of grants 
        awarded under this subsection for the first and second fiscal 
        years in which grants such are awarded shall not exceed 40 
        grants.
            ``(4) Authorization of appropriations.--There are 
        authorized to be appropriated to make grants under paragraph 
        (1), such sums as may be necessary for each of the fiscal years 
        1997 through 1999.
    ``(b) Innovative Medical Science Award.--
            ``(1) In general.--The Director of the National Center for 
        Research Resources shall make grants (to be referred to as 
        `innovative medical science awards') to support individual 
        clinical research projects.
            ``(2) Applications.--An application for a grant under this 
        subsection shall be submitted by an individual scientist at 
        such time as the Director requires.
            ``(3) Limitations.--The amount of a grant under this 
        subsection shall not exceed $100,000 per year per grant.
            ``(4) Authorization of appropriations.--There are 
        authorized to be appropriated to make grants under paragraph 
        (1), such sums as may be necessary for each of the fiscal years 
        1997 through 1999.
    ``(c) Peer Review.--The Director of NIH, in cooperation with the 
Director of the National Center for Research Resources, shall establish 
peer review mechanisms to evaluate applications for clinical research 
fellowships, clinical research career enhancement awards, and 
innovative medical science award programs. Such review mechanisms shall 
include individuals who are exceptionally qualified to appraise the 
merits of potential clinical research trainees.''.

SEC. 384. WAIVER OF LIMITATIONS.

    Section 481A (42 U.S.C. 287a-2) is amended--
            (1) in subsection (b)(3)(A), by striking ``9'' and 
        inserting ``12'';
            (2) in subsection (e)--
                    (A) in paragraph (1)--
                            (i) in subparagraph (A), by striking ``50'' 
                        and inserting ``40''; and
                            (ii) in subparagraph (B), by striking 
                        ``40'' and inserting ``30''; and
                    (B) in paragraph (4), by striking ``for applicants 
                meeting the conditions described in paragraphs (1) and 
                (2) of subsection (c)''; and
            (3) in subsection (h), by striking $150,000,000'' and all 
        that follows through ``1996'' and inserting ``such sums as may 
        be necessary for each of the fiscal years 1997 through 1999''.

                Subtitle J--National Library of Medicine

SEC. 391. AUTHORIZATION OF APPROPRIATIONS.

    Section 468(a) (42 U.S.C. 286a-2(a)) is amended by striking 
``$150,000,000'' and all that follows through the period and inserting 
``$160,000,000 for fiscal year 1997, and such sums as may be necessary 
for each of the fiscal years 1998 and 1999.''.

SEC. 392. INCREASING THE CAP ON GRANT AMOUNTS.

    Section 474(b)(2) (42 U.S.C. 286b-5(b)(2)) is amended by striking 
``$1,000,000'' and inserting ``$1,250,000''.

                     TITLE IV--AWARDS AND TRAINING

SEC. 401. MEDICAL SCIENTIST TRAINING PROGRAM.

    (a) Expansion of Program.--Notwithstanding any other provision of 
law, the Secretary of Health and Human Services, acting through the 
Director of the National Institutes of Health, shall expand the Medical 
Scientist Training Program to include fields that will contribute to 
training clinical investigators in the skills of performing patient-
oriented clinical research.
    (b) Designation of Slots.--In carrying out subsection (a), the 
Director of the National Institutes of Health shall designate a 
specific percentage of positions under the Medical Scientist Training 
Program for use with respect to the pursuit of a Ph.D. degree in the 
disciplines of economics, epidemiology, public health, bioengineering, 
biostatistics and bioethics, and other fields determined appropriate by 
the Director.

SEC. 402. RAISE IN MAXIMUM LEVEL OF LOAN REPAYMENTS.

    (a) Repayment Programs With Respect to AIDS.--Section 487A (42 
U.S.C. 288-1) is amended--
            (1) in subsection (a), by striking ``$20,000'' and 
        inserting ``$35,000''; and
            (2) in subsection (c), by striking ``1996'' and inserting 
        ``1999''.
    (b) Repayment Programs With Respect to Contraception and 
Infertility.--Section 487B(a) (42 U.S.C. 288-2(a)) is amended by 
striking ``$20,000'' and inserting ``$35,000''.
    (c) Repayment Programs With Respect to Research Generally.--Section 
487C(a)(1) (42 U.S.C. 288-3(a)(1)) is amended by striking ``$20,000'' 
and inserting ``$35,000''.
    (d) Repayment Programs With Respect to Clinical Researchers From 
Disadvantaged Backgrounds.--Section 487E(a) (42 U.S.C. 288-5(a)) is 
amended--
            (1) in paragraph (1), by striking ``$20,000'' and inserting 
        ``$35,000''; and
            (2) in paragraph (3), by striking ``338C'' and inserting 
        ``338B, 338C''.

SEC. 403. GENERAL LOAN REPAYMENT PROGRAM.

    Part G of title IV (42 U.S.C. 288 et seq.) is amended by inserting 
after section 487E, the following new section:

``SEC. 487F. GENERAL LOAN REPAYMENT PROGRAM.

    ``(a) Establishment.--
            ``(1) In general.--The Secretary, acting through the 
        Director of NIH, shall carry out a program of entering into 
        agreements with appropriately qualified health professionals 
        under which such health professionals agree to conduct research 
        with respect to the areas identified under paragraph (2) in 
        consideration of the Federal Government agreeing to repay, for 
        each year of such service, not more than $35,000 of the 
        principal and interest of the educational loans of such health 
        professionals.
            ``(2) Research areas.--In carrying out the program under 
        paragraph (1), the Director of NIH shall annually identify 
        areas of research for which loan repayments made be awarded 
        under paragraph (1).
            ``(3) Term of agreement.--A loan repayment agreement under 
        paragraph (1) shall be for a minimum of two years.
    ``(b) Applicability of Certain Provisions.--With respect to the 
National Health Service Corps Loan Repayment Program established in 
subpart III of part D of title III, the provisions of such subpart 
shall, except as inconsistent with subsection (a) of this section, 
apply to the program established in such subsection (a) in the same 
manner and to the same extent as such provisions apply to the National 
Health Service Corps Loan Repayment Program established in such 
subpart.
    ``(c) Authorization of Appropriations.--For the purpose of carrying 
out this section, there are authorized to be appropriated such sums as 
may be necessary for each of the fiscal years 1997 through 1999.''.

SEC. 404. CLINICAL RESEARCH ASSISTANCE.

    (a) National Research Service Awards.--Section 487(a)(1)(C) (42 
U.S.C. 288(a)(1)(C)) is amended--
            (1) by striking ``50 such'' and inserting ``100 such''; and
            (2) by striking ``1996'' and inserting ``1999''.
    (b) Loan Repayment Program.--Section 487E (42 U.S.C. 288-5) is 
amended--
            (1) in the section heading, by striking ``from 
        disadvantaged backgrounds'';
            (2) in subsection (a)(1), by striking ``who are from 
        disadvantaged backgrounds'';
            (3) in subsection (b)--
                    (A) by striking ``Amounts'' and inserting the 
                following:
            ``(1) In general.--Amounts''; and
                    (B) by adding at the end thereof the following new 
                paragraph:
            ``(2) Disadvantaged backgrounds set-aside.--In carrying out 
        this section, the Secretary shall ensure that not less than 50 
        percent of the amounts appropriated for a fiscal year are used 
        for contracts involving those appropriately qualified health 
        professionals who are from disadvantaged backgrounds.''; and
            (4) by adding at the end thereof the following new 
        subsections:
    ``(c) Clinical Research Training Position.--A position shall be 
considered a clinical research training position under subsection 
(a)(1) if such position involves an individual serving in a general 
clinical research center or other organizations and institutions 
determined to be appropriate by the Director of NIH, or a physician 
receiving a clinical research career enhancement award or NIH 
intramural research fellowship.
    ``(d) Authorization of Appropriations.--There are authorized to be 
appropriated to carry out this section such sums as may be necessary 
for each fiscal year.''.

                 TITLE V--RESEARCH WITH RESPECT TO AIDS

SEC. 501. COMPREHENSIVE PLAN FOR EXPENDITURE OF AIDS APPROPRIATIONS.

    Section 2353(d)(1) (42 U.S.C. 300cc-40b(d)(1)) is amended by 
striking ``through 1996'' and inserting ``through 1999''.

SEC. 502. EMERGENCY AIDS DISCRETIONARY FUND.

    Section 2356(g)(1) (42 U.S.C. 300cc-43(g)(1)) is amended by 
striking ``$100,000,000'' and all that follows through the period and 
inserting ``such sums as may be necessary for each of the fiscal years 
1997 through 1999''.

                      TITLE VI--GENERAL PROVISIONS

              Subtitle A--Authority of the Director of NIH

SEC. 601. AUTHORITY OF THE DIRECTOR OF NIH.

    Section 402(b) (42 U.S.C. 282(b)) is amended--
            (1) in paragraph (11), by striking ``and'' at the end 
        thereof;
            (2) in paragraph (12), by striking the period and inserting 
        a semicolon; and
            (3) by adding after paragraph (12), the following new 
        paragraphs:
            ``(13) may conduct and support research training--
                    ``(A) for which fellowship support is not provided 
                under section 487; and
                    ``(B) which does not consist of residency training 
                of physicians or other health professionals; and
            ``(14) may appoint physicians, dentists, and other health 
        care professionals, subject to the provisions of title 5, 
        United States Code, relating to appointments and 
        classifications in the competitive service, and may compensate 
        such professionals subject to the provisions of chapter 74 of 
        title 38, United States Code.''.

              Subtitle B--Office of Rare Disease Research

SEC. 611. ESTABLISHMENT OF OFFICE FOR RARE DISEASE RESEARCH.

    Part A of title IV of the Public Health Service Act (42 U.S.C. 281 
et seq.) is amended by adding at the end thereof the following new 
section:

``SEC. 404F. OFFICE FOR RARE DISEASE RESEARCH.

    ``(a) Establishment.--There is established within the Office of the 
Director of the National Institutes of Health an office to be known as 
the Office for Rare Disease Research (in this section referred to as 
the `Office'). The Office shall be headed by a director, who shall be 
appointed by the Director of the National Institutes of Health.
    ``(b) Purpose.--The purpose of the Office is to promote and 
coordinate the conduct of research on rare diseases through a strategic 
research plan and to establish and manage a rare disease research 
clinical database.
    ``(c) Advisory Council.--The Secretary shall establish an advisory 
council for the purpose of providing advice to the director of the 
Office concerning carrying out the strategic research plan and other 
duties under this section. Section 222 shall apply to such council to 
the same extent and in the same manner as such section applies to 
committees or councils established under such section.
    ``(d) Duties.--In carrying out subsection (b), the director of the 
Office shall--
            ``(1) develop a comprehensive plan for the conduct and 
        support of research on rare diseases;
            ``(2) coordinate and disseminate information among the 
        institutes and the public on rare diseases;
            ``(3) support research training and encourage the 
        participation of a diversity of individuals in the conduct of 
        rare disease research;
            ``(4) identify projects or research on rare diseases that 
        should be conducted or supported by the National Institutes of 
        Health;
            ``(5) develop and maintain a central database on current 
        government sponsored clinical research projects for rare 
        diseases;
            ``(6) determine the need for registries of research 
        subjects and epidemiological studies of rare disease 
        populations; and
            ``(7) prepare biennial reports on the activities carried 
        out or to be carried out by the Office and submit such reports 
        to the Secretary and the Congress.''.

                  Subtitle C--Certain Reauthorizations

SEC. 621. NATIONAL RESEARCH SERVICE AWARDS.

    Section 487(d) (42 U.S.C. 288(d)) is amended by striking 
``$400,000,000'' and all that follows through the first period and 
inserting ``such sums as may be necessary for each of the fiscal years 
1997 through 1999.''.

SEC. 622. NATIONAL FOUNDATION FOR BIOMEDICAL RESEARCH.

    Section 499(m)(1) (42 U.S.C. 290b(m)(1)) is amended by striking 
``an aggregate'' and all that follows through the period and inserting 
``such sums as may be necessary for each of the fiscal years 1997 
through 1999''.

                  Subtitle D--Miscellaneous Provisions

SEC. 631. ESTABLISHMENT OF NATIONAL FUND FOR HEALTH RESEARCH.

    Part A of title IV (42 U.S.C. 281 et seq.), as amended by section 
611, is further amended by adding at the end thereof the following new 
section:

``SEC. 404G. ESTABLISHMENT OF NATIONAL FUND FOR HEALTH RESEARCH.

    ``(a) Establishment.--There is established in the Treasury of the 
United States a fund, to be known as the `National Fund for Health 
Research' (hereafter in this section referred to as the `Fund'), 
consisting of such amounts as are transferred to the Fund and any 
interest earned on investment of amounts in the Fund.
    ``(b)  Obligations From Fund.--
            ``(1) In general.--Subject to the provisions of paragraph 
        (2), with respect to the amounts made available in the Fund in 
        a fiscal year, the Secretary shall distribute all of such 
        amounts during any fiscal year to research institutes and 
        centers of the National Institutes of Health in the same 
        proportion to the total amount received under this section, as 
        the amount of annual appropriations under appropriations Acts 
        for each member institute and centers for the fiscal year bears 
        to the total amount of appropriations under appropriations Acts 
        for all research institutes and centers of the National 
        Institutes of Health for the fiscal year.
            ``(2) Trigger and release of monies.--No expenditure shall 
        be made under paragraph (1) during any fiscal year in which the 
        annual amount appropriated for the National Institutes of 
        Health is less than the amount so appropriated for the prior 
        fiscal year.''.

SEC. 632. DEFINITION OF CLINICAL RESEARCH.

    Part A of title V (42 U.S.C. 281 et seq.) as amended by sections 
611 and 631, is further amended by adding at the end thereof the 
following new section:

``SEC. 404H. DEFINITION OF CLINICAL RESEARCH.

    ``As used in this title, the term `clinical research' means patient 
oriented clinical research conducted with human subjects, or research 
on the causes and consequences of disease in human populations, or on 
material of human origin (such as tissue specimens and cognitive 
phenomena) for which an investigator or colleague directly interacts 
with human subjects in an outpatient or inpatient setting to clarify a 
problem in human physiology, pathophysiology, or disease, epidemiologic 
or behavioral studies, outcomes research, or health services 
research.''.

SEC. 633. SENIOR BIOMEDICAL RESEARCH SERVICE.

    Section 228 (42 U.S.C. 237) is amended by adding at the end thereof 
the following new subsection:
    ``(h) Notwithstanding any other provision of law, the Secretary 
shall be treated as a non-profit entity for the purposes of making 
contributions to the retirement systems of appointees under this 
section in a manner that will permit such appointees to continue to be 
fully covered under the retirement systems that such appointees were 
members of immediately prior to their appointment under this 
section.''.

             Subtitle E--Repeals and Conforming Amendments

SEC. 641. REPEALS AND CONFORMING AMENDMENTS.

    (a) Renaming of Division of Research Resources.--Section 403(5) (42 
U.S.C. 283(5)) is amended by striking ``Division of Research 
Resources'' and inserting ``National Center for Research Resources''.
    (b) Renaming of National Center for Nursing Research.--
            (1) Section 403(5) (42 U.S.C. 283(5)) is amended by 
        striking ``National Center for Nursing Research'' and inserting 
        ``National Institute of Nursing Research''.
            (2) Section 408(a)(2) (42 U.S.C. 284c(a)(2)) is amended by 
        striking ``National Center for Nursing Research'' and inserting 
        ``National Institute of Nursing Research''.
    (c) Renaming of Chief Medical Director for Veterans Affairs.--
            (1) Section 406 (42 U.S.C. 284a) is amended--
                    (A) in subsection (b)(2)(A), by striking ``Chief 
                Medical Director of the Department of Veterans Affairs 
                or the Chief Dental Director of the Department of 
                Veterans Affairs'' and inserting ``Under Secretary for 
                Health of the Department of Veterans Affairs''; and
                    (B) in subsection (h)(2)(A)(v) by striking ``Chief 
                Medical Director of the Department of Veterans 
                Affairs,'' and inserting ``Under Secretary for Health 
                of the Department of Veterans Affairs''.
            (2) Section 424(c)(3)(B)(x) (42 U.S.C. 285b-7(c)(3)(B)(x)) 
        is amended by striking ``Chief Medical Director of the 
        Veterans' Administration'' and inserting ``Under Secretary for 
        Health of the Department of Veterans Affairs''.
            (3) Section 429(b) (42 U.S.C. 285c-3(b)) is amended by 
        striking ``Chief Medical Director of the Veterans' 
        Administration'' and inserting ``Under Secretary for Health of 
        the Department of Veterans Affairs''.
            (4) Section 430(b)(2)(A)(i) (42 U.S.C. 285c-4(b)(2)(A)(i)) 
        is amended by striking ``Chief Medical Director of the 
        Department of Veterans Affairs'' and inserting ``Under 
        Secretary for Health of the Department of Veterans Affairs''.
            (5) Section 439(b) (42 U.S.C. 285d-4(b)) is amended by 
        striking ``Chief Medical Director of the Department of Veterans 
        Affairs'' and inserting ``Under Secretary for Health of the 
        Department of Veterans Affairs''.
            (6) Section 452(f)(3)(B)(ix) (42 U.S.C. 285g-
        4(f)(3)(B)(ix)) is amended by striking ``Chief Medical Director 
        of the Department of Veterans Affairs'' and inserting ``Under 
        Secretary for Health of the Department of Veterans Affairs''.
            (7) Section 466(a)(1)(B) (42 U.S.C. 286a(a)(1)(B)) is 
        amended by striking ``Chief Medical Director of the Department 
        of Veterans Affairs'' and inserting ``Under Secretary for 
        Health of the Department of Veterans Affairs''.
            (8) Section 480(b)(2)(A) (42 U.S.C. 287a(b)(2)(A)) is 
        amended by striking ``Chief Medical Director of the Department 
        of Veterans Affairs'' and inserting ``Under Secretary for 
        Health of the Department of Veterans Affairs''.
    (b) Advisory Councils.--Section 406(h) (42 U.S.C. 284a(h)) is 
amended--
            (1) by striking paragraph (1); and
            (2) in paragraph (2)--
                    (A) by striking ``(2)(A) The'' and inserting ``(1) 
                The'';
                    (B) by redesignating subparagraph (B) as paragraph 
                (2); and
                    (C) by redesignating clauses (i) through (vi) of 
                paragraph (1) (as so redesignated) as subparagraphs (A) 
                through (F), respectively.
    (c) Diabetes and Digestive and Kidney Disorders Advisory Boards.--
Section 430 (42 U.S.C. 285c-4) is repealed.
    (d) National Arthritis and Musculoskeletal and Skin Diseases 
Advisory Board.--Section 442 (42 U.S.C. 285d-7) is repealed.
    (e) Research Centers Regarding Chronic Fatigue Syndrome.--Subpart 6 
of part C of title IV (42 U.S.C. 285f et seq.) is amended by 
redesignating the second section 447 (42 U.S.C. 285f-1) as section 
447A.
    (f) National Institute on Deafness Advisory Board.--Section 464D 
(42 U.S.C. 285m-4) is repealed.
    (g) Biomedical and Behavioral Research Personnel Study.--Section 
489 (42 U.S.C. 288b) is amended--
            (1) by striking subsections (b); and
            (2) by redesignating subsection (c) as subsection (b).
    (h) National Commission on Alcoholism and Other Alcohol-Related 
Problems.--Section 18 of the Comprehensive Alcohol Abuse and Alcoholism 
Prevention, Treatment, and Rehabilitation Act Amendments of 1979 (42 
U.S.C. 4541 note) is repealed.
    (i) Advisory Council on Hazardous Substances Research and 
Training.--Section 311(a) of the Comprehensive Environmental Response, 
Compensation and Liability Act of 1980 (42 U.S.C. 9660(a)) is amended--
            (1) by striking paragraph (5); and
            (2) in the last sentence of paragraph (6), by striking 
        ``the relevant Federal agencies referred to in subparagraph (A) 
        of paragraph (5)'' and inserting ``relevant Federal agencies''.
                                 <all>