Prohibits knowingly: (1) selling, buying, transporting, delivering, or receiving, for purposes of transportation in interstate or foreign commerce, any dog or other animal to participate in an animal fighting venture; (2) using interstate mail service for commercial speech promoting an animal fighting venture except as performed outside the limits of the states (with an exception for bird fights in states whose laws allow them); or (3) selling, buying, transporting, or delivering in interstate or foreign commerce a knife, gaff, or other sharp instrument to be attached to the leg of a bird for use in an animal fighting venture.

Increases the penalties to a fine and up to three years' imprisonment for violations.

Prohibits knowingly: (1) sponsoring or exhibiting a bird in a fighting venture in a state where it would not otherwise be a violation of the law if the person knew that any bird in the venture was knowingly bought, sold, delivered, transported, or received in interstate or foreign commerce for such purpose; (2) selling, buying, transporting, delivering, or receiving for purposes of transportation, in interstate or foreign commerce, any dog or other animal to participate in an animal fighting venture; (3) using the mails or any instrumentality of interstate commerce for commercial speech to promote an animal fighting venture, except as performed outside the limits of the states (with an exception for bird fights in states whose laws allow them); or (4) selling, buying, transporting, or delivering in interstate or foreign commerce a knife, gaff, or other sharp instrument for attachment to the leg of a bird for use in an animal fighting venture.

Imposes a fine and/or prison term of up to three years for violations. Repeals lesser penalties imposed by the Animal Welfare Act.