Amends the Controlled Substances Import and Export Act (CSIEA) to: (1) restrict the importation of ephedrine, pseudoephedrine, or phenylpropanolamine, with an exception; and (2) require a registered person importing such chemicals to include all information known regarding the chain of distribution. Authorizes the Attorney General to prohibit the importation of such chemicals in cases where a distributor refuses to provide such information.

Amends the Foreign Assistance Act of 1961 to: (1) require the President, annually, to identify the countries that are the five largest exporters of methamphetamine precursor chemicals and the five largest importers with the highest rate of diversion of such chemicals to the illicit production of methamphetamine; and (2) include those countries among drug-producing or drug-transit countries from which foreign assistance funds may be withheld. Directs the Secretary of State to: (1) submit to Congress a comprehensive plan to address such diversion; and (2) take steps to prevent methamphetamine smuggling into the United States from Mexico.

Amends CSA to lower the threshold for amounts of methamphetamine the manufacture, distribution, dispensation, possession, importation, or exportation of which is subject to specified penalties. Directs the Secretary of Transportation and the Administrator of the Environmental Protection Agency (EPA) to designate as hazardous materials or hazardous waste specified byproducts of the methamphetamine production process. Expands the scope of provisions regarding restitution for the cleanup of clandestine laboratory sites.

Allows (currently, requires) the Attorney General to reinstate the exemption of particular ephedrine, pseudoephedrine, or phenylpropanolamine drug products from inclusion as a "regulated transaction" if the Attorney General determines that the drug product is manufactured and distributed in a manner that prevents diversion.

Provides that references to ephedrine, pseudoephedrine, and phenylpropanolamine include each of the salts, optical isomers, and salts of optical isomers of such chemicals.

(Sec. 102) Includes ephedrine, pseudoephedrine, and phenylpropanolamine among the substances for which the Attorney General must establish production quotas.

(Sec. 103) Prohibits a person from manufacturing ephedrine, pseudoephedrine, or phenylpropanolamine that is: (1) not expressly authorized by such person's registration with the Attorney General and by a quota assigned to that person; or (2) in excess of the assigned quota.

(Sec. 104) Amends the Controlled Substances Import and Export Act to prohibit the importation into the United States of ephedrine, pseudoephedrine, or phenylpropanolamine, except in amounts the Attorney General allows as necessary to provide for medical, scientific, or other legitimate purposes. Allows a registrant who is authorized to import such a chemical to apply for an increase in the amount authorized.

(Sec. 105) Prohibits a regular importer from transferring a listed chemical to a transferee that is not a regular customer until 15 days after notice is submitted to the Attorney General. Prohibits any change in the prospective transferee until 15 days after an update of such notice is submitted to the Attorney General, unless that transferee is a regular customer. Provides that the transferee involved shall then be considered to qualify as a regular customer, unless the Attorney General otherwise notifies the importer or exporter. Allows the Attorney General to suspend such a transfer on the ground that the chemical may be diverted to the illegal or clandestine manufacture of a controlled substance.

(Sec. 106) Imposes penalties for: (1) importing a listed chemical in violation of established quota requirements; or (2) transferring such a chemical in violation of notice requirements.

Title II: International Regulation of Precursor Chemicals - (Sec. 201) Requires a regulated person importing ephedrine, pseudoephedrine, or phenylpropanolamine to include in the notice of importation all information known to the importer on the chain of distribution of such chemical from the manufacturer to the importer. Allows the Attorney General to: (1) request that a distributor of such chemical provide information known to the distributor on the distribution of the chemical, including sales; and (2) prohibit the importation of such chemical in any case in which a foreign-chain distributor that is refusing to cooperate with the Attorney General in obtaining chain-of-custody information is part of the chain of distribution.

(Sec. 202) Amends the Foreign Assistance Act of 1961 to require an additional section in the President's international narcotics control strategy report that: (1) identifies the five countries that exported the largest amount of pseudoephedrine, ephedrine, and phenylpropanolamine; (2) identifies the five countries that imported the largest amount of such chemicals and have the highest rate of diversion of such chemicals for the use in the illicit production of methamphetamine; and (3) includes an economic analysis of the total worldwide production of such chemicals compared to the legitimate demand for such chemicals. Withholds 50% of the U.S. assistance allocated each fiscal year for countries so identified unless the country has either cooperated fully with the United States or has taken adequate steps on its own to achieve full compliance with established United Nations goals and objectives, unless the vital national interests of the United States prevent withholding such funds.

Requires the Secretary of State to submit to Congress a comprehensive plan to address the diversion of chemicals to the illicit production of methamphetamine for each identified country for which the President has not submitted a certification of full cooperation.

Authorizes appropriations for FY2006-FY2007.

(Sec. 203) Requires the Secretary of State, acting through the Assistant Secretary of the Bureau for International Narcotics and Law Enforcement Affairs, to take necessary actions to prevent the smuggling of methamphetamine into the United States from Mexico. Requires the Secretary of State to: (1) improve bilateral effort at the border; (2) seek to work with Mexican law enforcement authorities to improve the ability of such authorities to combat the production and trafficking of methamphetamine; and (3) encourage Mexico to take immediate action to reduce the diversion of pseudoephedrine.

Sets forth reporting requirements.

Authorizes appropriations.

Title III: Enhanced Criminal Penalties for Methamphetamine Production and Trafficking - (Sec. 301) Amends the Controlled Substances Act to impose penalties upon any person who knowingly or intentionally possesses ephedrine, pseudoephedrine, or phenylpropanolamine with intent to manufacture a controlled substance.

(Sec. 302) Increases penalties for violations of the Controlled Substances Act or the Controlled Substances Import and Export Act involving methamphetamine to increase the term of imprisonment by not more than 15 years if the person was enrolled in, and used in committing the offense, any dedicated commuter lane, alternative or accelerated inspection system, or other facilitated entry program administered or approved by the federal government for use in entering the United States. Bars such a person from using any such lane, system, or program permanently.

(Sec. 303) Sets forth additional penalties for violations of the Controlled Substances Act that involve the manufacture of a controlled substance on federal property.

(Sec. 304) Sets forth the circumstances under which the leader of a continuing criminal enterprise involving methamphetamine can receive life imprisonment.

(Sec. 305) Increases penalties for violating the Controlled Substances Act by manufacturing or distributing, or possessing with intent to manufacture or distribute, methamphetamine on premises in which an individual who is under the age of 18 years is present or resides.

(Sec. 306) Amends the federal judicial code to require that information submitted by the Chief Judge of the District Court regarding the imposition of sentences in criminal cases be in a format approved and required by the United States Sentencing Commission.

(Sec. 307) Requires the Attorney General to report to relevant congressional committees and organizations semiannually on: (1) the allocation of resources of the Drug Enforcement Administration (DEA) and the Federal Bureau of Investigation (FBI) for the investigation and prosecution of alleged violations of the Controlled Substances Act involving methamphetamine; and (2) the measures being taken to give priority in resource allocation to violations involving the importation of substantial quantities of methamphetamine, or ephedrine, pseudoephedrine, or phenylpropanolamine, the manufacture of methamphetamine, and circumstances that have endangered children.

Title IV: Enhanced Environmental Regulation of Methamphetamine By-Products - (Sec. 401) Requires the Secretary of Transportation to designate as hazardous materials for transportation purposes by-products of the methamphetamine-production process that may pose an unreasonable risk to health and safety or property when transported in commerce.

Requires the Administrator of the Environmental Protection Agency (EPA) to designate as hazardous waste for Solid Waste Disposal Act purposes by-products of the methamphetamine-production process that are likely to cause long-term harm to the environment in the event of improper disposal and inadequate remediation.

(Sec. 402) Requires the court to assess restitution or reimbursement penalties: (1) on defendants convicted of offenses involving possession, or possession with the intent to distribute, of amphetamine or methamphetamine; and (2) that include the cost of cleanup on premises or in property that the defendant owns, resides, or does business.

Title V: Additional Programs and Activities - (Sec. 501) Amends the Omnibus Crime Control and Safe Streets Act of 1968 to allow drug court grants to only be given to courts with mandatory periodic testing for the use of controlled substances or other addictive substances during supervised release or probation. Requires the Attorney General to specify standards for such testing to ensure that: (1) each participant is tested for every controlled substance that the participant has been known to abuse and for any other controlled substance the Attorney General or the court may require; and (2) the testing is accurate and practicable. Allows such standards to require approval of the drug testing regime to ensure that adequate testing occurs.

Requires the Attorney General to specify that grant amounts may be used only for drug courts that impose graduated sanctions that increase punitive measures, therapeutic measures, or both whenever a participant fails a drug test.

(Sec. 502) Authorizes the Attorney General, through the Bureau of Justice Assistance in the Office of Justice Programs, to make grants to states to address the manufacture, sale, and use of methamphetamine to enhance public safety. Allows such grants to be used to: (1) investigate, arrest, and prosecute individuals violating laws related to the use, manufacture, or sale of methamphetamine; (2) reimburse DEA for expenses related to the cleanup of methamphetamine clandestine labs and related environmental damage; (3) support state and local health departments and environmental agency services deployed to address methamphetamine; and (4) procure equipment, technology, or support systems, or pay for resources, if those expenditures will result in the reduction in the use, sale, and manufacture of methamphetamine.

Authorizes appropriations.

(Sec. 503) Directs the Attorney General to make grants to states to provide a comprehensive response to aid children who are living in a home in which methamphetamine or other controlled substances are unlawfully manufactured, administered, or distributed. Requires the Attorney General to ensure that such response includes: (1) coordination among law enforcement agencies, prosecutors, child protective services, and health professionals; and (2) removal of children from toxic or drug-endangering environments.

Authorizes appropriations.

Prohibits the retail sale of more than 3.6 grams per day of any ephedrine base, pseudoephedrine base, or phenylpropanolamine base in a scheduled listed chemical product to any purchaser without regard to the number of transactions.

Prohibits a seller or distributor from selling at retail such a product in a nonliquid form (including gell caps) unless the product is packaged in blister packs if technically feasible or otherwise packaged in unit dose packets or pouches. Defines "at retail" as the sale or purchase for personal use of a scheduled listed chemical product.

Requires a seller to: (1) place scheduled listed chemical products where customers do not have direct access to them before sale (behind-the-counter placement); (2) deliver such products directly into the custody of the purchaser; (3) maintain a logbook of sales that identifies the products by name, quantity, purchaser name and address, and dates and times of sale, except for any purchase by an individual of a single sales package of not more than 60 milligrams of pseudoephedrine; (4) maintain such logbook entries for not fewer than two years; and (5) submit to the Attorney General a self-certification that all individuals responsible for delivering or selling such products have undergone training on the requirements. Prohibits a seller from selling such a product unless: (1) the prospective purchaser presents an identification card and signs the logbook; and (2) the seller verifies that the name in the logbooks corresponds to the identification and enters the name of the product and quantity sold.

Requires mobile retail vendors to: (1) place scheduled listed chemical products in a locked cabinet; and (2) not sell more than 7.5 grams of ephedrine base, pseudoephedrine base, or phenylpropanolamine base in such products per customer during a 30-day period. Defines "mobile retail vendor" as a person or entity that makes sales at retail from a stand that is intended to be temporary or is capable of being moved from one location to another.

Prohibits a regulated seller from selling any scheduled listed chemical product at retail without first submitting to the Attorney General the required training self-certification. Requires the Attorney General to establish: (1) criteria for certifications, including that certifications are required for each place of business at which a regulated seller sells such products at retail; and (2) restrictions on the disclosure of information in logbooks to protect the privacy of individuals who purchase such products. Defines "regulated seller" as a retail distributor (including a pharmacy or a mobile retail vendor), except not an employee or agent of such distributor.

Includes information in the logbook as a matter within the jurisdiction of the executive, legislative, or judicial branch of the government of the United States in order to prohibit and provide penalties for knowingly and willfully: (1) making any materially false, fictitious, or fraudulent statement or representation; or (2) making or using any false writing or document knowing that it contains any materially false, fictitious, or fraudulent statement or entry.

Provides immunity from civil liability to any regulated seller who in good faith releases information in a logbook to a federal, state, or local law enforcement authority unless such release constitutes gross negligence or intentional, wanton, or willful misconduct.

Allows a regulated seller to take reasonable measures to guard against employing individuals who may present a risk of theft and diversion of scheduled listed chemical products, including by asking employment applicants whether they have been convicted of any crime involving or related to such products or controlled substances.

Requires a regulated person who makes a sale at retail of a scheduled listed chemical product, and who uses or attempts to use the Postal Service or any private or commercial carrier, to confirm the identity of the purchaser prior to shipping the product. Prohibits such a sale of more than 7.5 grams of ephedrine base, pseudoephedrine base, or phenylpropanolamine base in such products per customer during a 30-day period.

Allows the Attorney General to exempt certain scheduled listed chemical products from sales transaction requirements if the Attorney General determines that the product cannot be used in the illicit manufacture of methamphetamine.

Prohibits: (1) selling at retail a scheduled listed chemical product knowing at the time of the transaction (independent of consulting the logbook) that the transaction is a violation of the CSA; (2) knowingly or recklessly selling at retail such product in violation of the blister pack, behind-the-counter, or logbook requirements; and (3) disclosing information in logbooks in violation of privacy requirements or refusing to provide a logbook to federal, state, or local law enforcement authorities.

Authorizes the Attorney General to prohibit a seller or distributor that fails to meet reporting requirements from selling any scheduled listed chemical product.

(Sec. 102) Amends the definition of "regulated transaction" to include any transaction in a scheduled listed chemical product. Makes conforming amendments to the CSA and the Comprehensive Methamphetamine Control Act of 1996.

(Sec. 103) Includes ephedrine, pseudoephedrine, and phenylpropanolamine among the substances for which the Attorney General must establish production quotas.

(Sec. 104) Prohibits a person from manufacturing ephedrine, pseudoephedrine, or phenylpropanolamine that is: (1) not expressly authorized by such person's registration with the Attorney General and by a quota assigned to that person; or (2) in excess of the assigned quota.

(Sec. 105) Amends the Controlled Substances Import and Export Act to prohibit the importation into the United States of ephedrine, pseudoephedrine, or phenylpropanolamine, except in amounts the Attorney General allows as necessary to provide for medical, scientific, or other legitimate purposes. Allows a registrant who is authorized to import such a chemical to apply for an increase in the amount authorized.

(Sec. 106) Prohibits a regular importer from transferring a listed chemical to a transferee that is not a regular customer until 15 days after notice is submitted to the Attorney General. Prohibits any change in the prospective transferee until 15 days after an update of such notice is submitted to the Attorney General, unless that transferee is a regular customer. Provides that the transferee involved shall then be considered to qualify as a regular customer, unless the Attorney General otherwise notifies the importer or exporter. Allows the Attorney General to suspend such a transfer on the ground that the chemical may be diverted to the illegal or clandestine manufacture of a controlled substance.

Requires the importer or exporter to send to the Attorney General within 30 days of such a transaction a return declaration containing particulars of the transaction. Requires an importer that has not distributed all chemicals within 30 days to file supplemental return declarations for other distributions or dispositions.

(Sec. 107) Sets forth penalties for: (1) importing a listed chemical in violation of established quota requirements; or (2) transferring such a chemical in violation of notice requirements.

(Sec. 108) Requires the Attorney General to consult with the U.S. Trade Representative to ensure that implementation of relevant sections of this Act complies with all applicable international treaties and obligations.

Title II: International Regulation of Precursor Chemicals - (Sec. 201) Requires a regulated person importing ephedrine, pseudoephedrine, or phenylpropanolamine to include in the notice of importation all information known to the importer on the chain of distribution of such chemical from the manufacturer to the importer. Allows the Attorney General to: (1) request that a distributor of such chemical provide information on its distribution, including sales; and (2) prohibit the importation of such chemical in any case in which a foreign-chain distributor that is refusing to cooperate with the Attorney General in obtaining chain-of-custody information is part of the chain of distribution.

(Sec. 202) Amends the Foreign Assistance Act of 1961 to require an additional section in the President's international narcotics control strategy report that: (1) identifies the five countries that exported the largest amount of pseudoephedrine, ephedrine, and phenylpropanolamine; (2) identifies the five countries that imported the largest amount of such chemicals and have the highest rate of diversion of such chemicals for the use in the illicit production of methamphetamine; and (3) includes an economic analysis of the total worldwide production of such chemicals compared to the legitimate demand for such chemicals. Withholds 50% of the US assistance allocated each fiscal year for countries so identified unless the country has either cooperated fully with the United States or has taken adequate steps on its own to achieve full compliance with established United Nations goals and objectives, unless the vital national interests of the United States prevent withholding such funds.

Requires the Secretary of State to submit to Congress a comprehensive plan to address the diversion of chemicals to the illicit production of methamphetamine for each identified country for which the President has not submitted a certification of full cooperation.

Authorizes appropriations for FY2006-FY2007.

(Sec. 203) Requires the Secretary of State, acting through the Assistant Secretary of the Bureau for International Narcotics and Law Enforcement Affairs, to take necessary actions to prevent the smuggling of methamphetamine into the United States from Mexico. Requires the Secretary of State to: (1) improve bilateral effort at the border; (2) seek to work with Mexican law enforcement authorities to improve the ability of such authorities to combat the production and trafficking of methamphetamine; and (3) encourage Mexico to take immediate action to reduce the diversion of pseudoephedrine. Sets forth reporting requirements. Authorizes appropriations.

Title III: Enhanced Criminal Penalties for Methamphetamine Production and Trafficking - (Sec. 301) Decreases the quantities of methamphetamine the manufacture, distribution, dispensation, possession (with intent to manufacture, distribute, or dispense), importation, or exportation of which will result in sentences of imprisonment for at least five years or for ten years to life.

(Sec. 302) Increases penalties for violations of the CSA or the Controlled Substances Import and Export Act involving methamphetamine to increase the term of imprisonment by not more than 15 years if the person: (1) was enrolled in any dedicated commuter lane, alternative or accelerated inspection system, or other facilitated entry program administered or approved by the federal government for use in entering the United States; and (2) committed the offense while entering the United States using such lane, system, or program. Bars such a person from being eligible for or using any such lane, system, or program permanently.

(Sec. 303) Sets forth additional penalties for violations of the CSA that involve the manufacture of a controlled substance on federal property.

(Sec. 304) Sets forth the quantities and gross receipts for which the leader of a continuing criminal enterprise involving methamphetamine can receive life imprisonment.

Title IV: Enhanced Environmental Regulation of Methamphetamine By-Products - (Sec. 401) Requires the Secretary of Transportation to report biennially to the House Committee on Transportation and Infrastructure and the Senate Committee on Commerce, Science, and Transportation on whether the Secretary has designated as hazardous materials for transportation purposes all byproducts of the methamphetamine-production process that are known to pose an unreasonable risk to health and safety or property when transported in commerce.

(Sec. 402) Amends the Solid Waste Disposal Act to require the Administrator of the Environmental Protection Agency (EPA) to report biennially to the House Committee on Energy and Commerce and the Senate Committee on Environment and Public Works on information collected from law enforcement agencies, states, and other relevant stakeholders that identifies the byproducts of the methamphetamine production process and on whether the Administrator considers the byproducts to be a hazardous waste for purposes of such Act.

(Sec. 403) Amends the CSA to require the court to assess restitution or reimbursement penalties: (1) on defendants convicted of offenses involving the possession, or the possession with the intent to distribute, of amphetamine or methamphetamine; and (2) that include the cost of cleanup on premises or in property that the defendant owns, resides, or does business.